Guide to the Human Genome
Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Search of human proteins with 237757310

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|237757310 synaptojanin 1 isoform a [Homo sapiens]
         (1612 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|237757310 synaptojanin 1 isoform a [Homo sapiens]                 3244   0.0  
gi|237757326 synaptojanin 1 isoform d [Homo sapiens]                 3019   0.0  
gi|237757308 synaptojanin 1 isoform b [Homo sapiens]                 2703   0.0  
gi|237757312 synaptojanin 1 isoform c [Homo sapiens]                 2575   0.0  
gi|26190608 synaptojanin 2 [Homo sapiens]                            1174   0.0  
gi|113722125 inositol polyphosphate-5-phosphatase, 75kDa precurs...   211   4e-54
gi|13325070 phosphatidylinositol polyphosphate 5-phosphatase iso...   206   1e-52
gi|13325072 phosphatidylinositol polyphosphate 5-phosphatase iso...   206   1e-52
gi|190014578 suppressor of actin 1 [Homo sapiens]                     203   1e-51
gi|7662414 inositol polyphosphate-5-phosphatase F [Homo sapiens]      192   3e-48
gi|40254823 SH2 containing inositol phosphatase isoform b [Homo ...   177   6e-44
gi|64085167 SH2 containing inositol phosphatase isoform a [Homo ...   177   6e-44
gi|50726960 phosphatidylinositol (4,5) bisphosphate 5-phosphatas...   162   3e-39
gi|222136583 inositol polyphosphate phosphatase-like 1 [Homo sap...   154   9e-37
gi|38327539 inositol polyphosphate-5-phosphatase E [Homo sapiens]     135   2e-31
gi|18765709 inositol polyphosphate-5-phosphatase K isoform 1 [Ho...   133   1e-30
gi|208610044 inositol polyphosphate-5-phosphatase K isoform 2 [H...   125   3e-28
gi|18765707 inositol polyphosphate-5-phosphatase K isoform 2 [Ho...   125   3e-28
gi|189181724 proteoglycan 4 isoform D [Homo sapiens]                   97   2e-19
gi|189181722 proteoglycan 4 isoform C [Homo sapiens]                   97   2e-19
gi|189181720 proteoglycan 4 isoform B [Homo sapiens]                   97   2e-19
gi|67190163 proteoglycan 4 isoform A [Homo sapiens]                    97   2e-19
gi|116284392 mucin 2 precursor [Homo sapiens]                          95   6e-19
gi|163965366 nascent polypeptide-associated complex alpha subuni...    94   1e-18
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    92   5e-18
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]          91   9e-18
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]          91   9e-18
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]          91   9e-18
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]     91   1e-17
gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [...    90   2e-17

>gi|237757310 synaptojanin 1 isoform a [Homo sapiens]
          Length = 1612

 Score = 3244 bits (8410), Expect = 0.0
 Identities = 1612/1612 (100%), Positives = 1612/1612 (100%)

Query: 1    MRKRWACWSGSDAPGGCGGGCGRRRRRSRRKRAASEERRMAFSKGFRIYHKLDPPPFSLI 60
            MRKRWACWSGSDAPGGCGGGCGRRRRRSRRKRAASEERRMAFSKGFRIYHKLDPPPFSLI
Sbjct: 1    MRKRWACWSGSDAPGGCGGGCGRRRRRSRRKRAASEERRMAFSKGFRIYHKLDPPPFSLI 60

Query: 61   VETRHKEECLMFESGAVAVLSSAEKEAIKGTYSKVLDAYGLLGVLRLNLGDTMLHYLVLV 120
            VETRHKEECLMFESGAVAVLSSAEKEAIKGTYSKVLDAYGLLGVLRLNLGDTMLHYLVLV
Sbjct: 61   VETRHKEECLMFESGAVAVLSSAEKEAIKGTYSKVLDAYGLLGVLRLNLGDTMLHYLVLV 120

Query: 121  TGCMSVGKIQESEVFRVTSTEFISLRIDSSDEDRISEVRKVLNSGNFYFAWSASGISLDL 180
            TGCMSVGKIQESEVFRVTSTEFISLRIDSSDEDRISEVRKVLNSGNFYFAWSASGISLDL
Sbjct: 121  TGCMSVGKIQESEVFRVTSTEFISLRIDSSDEDRISEVRKVLNSGNFYFAWSASGISLDL 180

Query: 181  SLNAHRSMQEQTTDNRFFWNQSLHLHLKHYGVNCDDWLLRLMCGGVEIRTIYAAHKQAKA 240
            SLNAHRSMQEQTTDNRFFWNQSLHLHLKHYGVNCDDWLLRLMCGGVEIRTIYAAHKQAKA
Sbjct: 181  SLNAHRSMQEQTTDNRFFWNQSLHLHLKHYGVNCDDWLLRLMCGGVEIRTIYAAHKQAKA 240

Query: 241  CLISRLSCERAGTRFNVRGTNDDGHVANFVETEQVVYLDDSVSSFIQIRGSVPLFWEQPG 300
            CLISRLSCERAGTRFNVRGTNDDGHVANFVETEQVVYLDDSVSSFIQIRGSVPLFWEQPG
Sbjct: 241  CLISRLSCERAGTRFNVRGTNDDGHVANFVETEQVVYLDDSVSSFIQIRGSVPLFWEQPG 300

Query: 301  LQVGSHRVRMSRGFEANAPAFDRHFRTLKNLYGKQIIVNLLGSKEGEHMLSKAFQSHLKA 360
            LQVGSHRVRMSRGFEANAPAFDRHFRTLKNLYGKQIIVNLLGSKEGEHMLSKAFQSHLKA
Sbjct: 301  LQVGSHRVRMSRGFEANAPAFDRHFRTLKNLYGKQIIVNLLGSKEGEHMLSKAFQSHLKA 360

Query: 361  SEHAADIQMVNFDYHQMVKGGKAEKLHSVLKPQVQKFLDYGFFYFNGSEVQRCQSGTVRT 420
            SEHAADIQMVNFDYHQMVKGGKAEKLHSVLKPQVQKFLDYGFFYFNGSEVQRCQSGTVRT
Sbjct: 361  SEHAADIQMVNFDYHQMVKGGKAEKLHSVLKPQVQKFLDYGFFYFNGSEVQRCQSGTVRT 420

Query: 421  NCLDCLDRTNSVQAFLGLEMLAKQLEALGLAEKPQLVTRFQEVFRSMWSVNGDSISKIYA 480
            NCLDCLDRTNSVQAFLGLEMLAKQLEALGLAEKPQLVTRFQEVFRSMWSVNGDSISKIYA
Sbjct: 421  NCLDCLDRTNSVQAFLGLEMLAKQLEALGLAEKPQLVTRFQEVFRSMWSVNGDSISKIYA 480

Query: 481  GTGALEGKAKLKDGARSVTRTIQNNFFDSSKQEAIDVLLLGNTLNSDLADKARALLTTGS 540
            GTGALEGKAKLKDGARSVTRTIQNNFFDSSKQEAIDVLLLGNTLNSDLADKARALLTTGS
Sbjct: 481  GTGALEGKAKLKDGARSVTRTIQNNFFDSSKQEAIDVLLLGNTLNSDLADKARALLTTGS 540

Query: 541  LRVSEQTLQSASSKVLKSMCENFYKYSKPKKIRVCVGTWNVNGGKQFRSIAFKNQTLTDW 600
            LRVSEQTLQSASSKVLKSMCENFYKYSKPKKIRVCVGTWNVNGGKQFRSIAFKNQTLTDW
Sbjct: 541  LRVSEQTLQSASSKVLKSMCENFYKYSKPKKIRVCVGTWNVNGGKQFRSIAFKNQTLTDW 600

Query: 601  LLDAPKLAGIQEFQDKRSKPTDIFAIGFEEMVELNAGNIVSASTTNQKLWAVELQKTISR 660
            LLDAPKLAGIQEFQDKRSKPTDIFAIGFEEMVELNAGNIVSASTTNQKLWAVELQKTISR
Sbjct: 601  LLDAPKLAGIQEFQDKRSKPTDIFAIGFEEMVELNAGNIVSASTTNQKLWAVELQKTISR 660

Query: 661  DNKYVLLASEQLVGVCLFVFIRPQHAPFIRDVAVDTVKTGMGGATGNKGAVAIRMLFHTT 720
            DNKYVLLASEQLVGVCLFVFIRPQHAPFIRDVAVDTVKTGMGGATGNKGAVAIRMLFHTT
Sbjct: 661  DNKYVLLASEQLVGVCLFVFIRPQHAPFIRDVAVDTVKTGMGGATGNKGAVAIRMLFHTT 720

Query: 721  SLCFVCSHFAAGQSQVKERNEDFIEIARKLSFPMGRMLFSHDYVFWCGDFNYRIDLPNEE 780
            SLCFVCSHFAAGQSQVKERNEDFIEIARKLSFPMGRMLFSHDYVFWCGDFNYRIDLPNEE
Sbjct: 721  SLCFVCSHFAAGQSQVKERNEDFIEIARKLSFPMGRMLFSHDYVFWCGDFNYRIDLPNEE 780

Query: 781  VKELIRQQNWDSLIAGDQLINQKNAGQVFRGFLEGKVTFAPTYKYDLFSDDYDTSEKCRT 840
            VKELIRQQNWDSLIAGDQLINQKNAGQVFRGFLEGKVTFAPTYKYDLFSDDYDTSEKCRT
Sbjct: 781  VKELIRQQNWDSLIAGDQLINQKNAGQVFRGFLEGKVTFAPTYKYDLFSDDYDTSEKCRT 840

Query: 841  PAWTDRVLWRRRKWPFDRSAEDLDLLNASFQDESKILYTWTPGTLLHYGRAELKTSDHRP 900
            PAWTDRVLWRRRKWPFDRSAEDLDLLNASFQDESKILYTWTPGTLLHYGRAELKTSDHRP
Sbjct: 841  PAWTDRVLWRRRKWPFDRSAEDLDLLNASFQDESKILYTWTPGTLLHYGRAELKTSDHRP 900

Query: 901  VVALIDIDIFEVEAEERQNIYKEVIAVQGPPDGTVLVSIKSSLPENNFFDDALIDELLQQ 960
            VVALIDIDIFEVEAEERQNIYKEVIAVQGPPDGTVLVSIKSSLPENNFFDDALIDELLQQ
Sbjct: 901  VVALIDIDIFEVEAEERQNIYKEVIAVQGPPDGTVLVSIKSSLPENNFFDDALIDELLQQ 960

Query: 961  FASFGEVILIRFVEDKMWVTFLEGSSALNVLSLNGKELLNRTITIALKSPDWIKNLEEEM 1020
            FASFGEVILIRFVEDKMWVTFLEGSSALNVLSLNGKELLNRTITIALKSPDWIKNLEEEM
Sbjct: 961  FASFGEVILIRFVEDKMWVTFLEGSSALNVLSLNGKELLNRTITIALKSPDWIKNLEEEM 1020

Query: 1021 SLEKISIALPSSTSSTLLGEDAEVAADFDMEGDVDDYSAEVEELLPQHLQPSSSSGLGTS 1080
            SLEKISIALPSSTSSTLLGEDAEVAADFDMEGDVDDYSAEVEELLPQHLQPSSSSGLGTS
Sbjct: 1021 SLEKISIALPSSTSSTLLGEDAEVAADFDMEGDVDDYSAEVEELLPQHLQPSSSSGLGTS 1080

Query: 1081 PSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQPATPLPQKDPAQ 1140
            PSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQPATPLPQKDPAQ
Sbjct: 1081 PSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQPATPLPQKDPAQ 1140

Query: 1141 PLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRKEFGGIGAPPSPGVARREMEAP 1200
            PLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRKEFGGIGAPPSPGVARREMEAP
Sbjct: 1141 PLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRKEFGGIGAPPSPGVARREMEAP 1200

Query: 1201 KSPGTTRKDNIGRSQPSPQAGLAGPGPAGYSTARPTIPPRAGVISAPQSHARASAGRLTP 1260
            KSPGTTRKDNIGRSQPSPQAGLAGPGPAGYSTARPTIPPRAGVISAPQSHARASAGRLTP
Sbjct: 1201 KSPGTTRKDNIGRSQPSPQAGLAGPGPAGYSTARPTIPPRAGVISAPQSHARASAGRLTP 1260

Query: 1261 ESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQEPLVPVAAPMPQSGPQPNLE 1320
            ESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQEPLVPVAAPMPQSGPQPNLE
Sbjct: 1261 ESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQEPLVPVAAPMPQSGPQPNLE 1320

Query: 1321 TPPQPPPRSRSSHSLPSEASSQPQVKTNGISDGKRESPLKIDPFEDLSFNLLAVSKAQLS 1380
            TPPQPPPRSRSSHSLPSEASSQPQVKTNGISDGKRESPLKIDPFEDLSFNLLAVSKAQLS
Sbjct: 1321 TPPQPPPRSRSSHSLPSEASSQPQVKTNGISDGKRESPLKIDPFEDLSFNLLAVSKAQLS 1380

Query: 1381 VQTSPVPTPDPKRLIQLPSATQSNVLSSVSCMPTMPPIPARSQSQENMRSSPNPFITGLT 1440
            VQTSPVPTPDPKRLIQLPSATQSNVLSSVSCMPTMPPIPARSQSQENMRSSPNPFITGLT
Sbjct: 1381 VQTSPVPTPDPKRLIQLPSATQSNVLSSVSCMPTMPPIPARSQSQENMRSSPNPFITGLT 1440

Query: 1441 RTNPFSDRTAAPGNPFRAKSEESEATSWFSKEEPVTISPFPSLQPLGHNKSRASSSLDGF 1500
            RTNPFSDRTAAPGNPFRAKSEESEATSWFSKEEPVTISPFPSLQPLGHNKSRASSSLDGF
Sbjct: 1441 RTNPFSDRTAAPGNPFRAKSEESEATSWFSKEEPVTISPFPSLQPLGHNKSRASSSLDGF 1500

Query: 1501 KDSFDLQGQSTLKISNPKGWVTFEEEEDFGVKGKSKSACSDLLGNQPSSFSGSNLTLNDD 1560
            KDSFDLQGQSTLKISNPKGWVTFEEEEDFGVKGKSKSACSDLLGNQPSSFSGSNLTLNDD
Sbjct: 1501 KDSFDLQGQSTLKISNPKGWVTFEEEEDFGVKGKSKSACSDLLGNQPSSFSGSNLTLNDD 1560

Query: 1561 WNKGTNVSFCVLPSRRPPPPPVPLLPPGTSPPVDPFTTLASKASPTLDFTER 1612
            WNKGTNVSFCVLPSRRPPPPPVPLLPPGTSPPVDPFTTLASKASPTLDFTER
Sbjct: 1561 WNKGTNVSFCVLPSRRPPPPPVPLLPPGTSPPVDPFTTLASKASPTLDFTER 1612


>gi|237757326 synaptojanin 1 isoform d [Homo sapiens]
          Length = 1526

 Score = 3019 bits (7826), Expect = 0.0
 Identities = 1519/1576 (96%), Positives = 1520/1576 (96%), Gaps = 53/1576 (3%)

Query: 40   MAFSKGFRIYHKLDPPPFSLIVETRHKEECLMFESGAVAVLSSAEKEAIKGTYSKVLDAY 99
            MAFSKGFRIYHKLDPPPFSLIVETRHKEECLMFESGAVAVLSSAEKEAIKGTYSKVLDAY
Sbjct: 1    MAFSKGFRIYHKLDPPPFSLIVETRHKEECLMFESGAVAVLSSAEKEAIKGTYSKVLDAY 60

Query: 100  GLLGVLRLNLGDTMLHYLVLVTGCMSVGKIQESEVFRVTSTEFISLRIDSSDEDRISEVR 159
            GLLGVLRLNLGDTMLHYLVLVTGCMSVGKIQESEVFRVTSTEFISLRIDSSDEDRISEVR
Sbjct: 61   GLLGVLRLNLGDTMLHYLVLVTGCMSVGKIQESEVFRVTSTEFISLRIDSSDEDRISEVR 120

Query: 160  KVLNSGNFYFAWSASGISLDLSLNAHRSMQEQTTDNRFFWNQSLHLHLKHYGVNCDDWLL 219
            KVLNSGNFYFAWSASGISLDLSLNAHRSMQEQTTDNRFFWNQSLHLHLKHYGVNCDDWLL
Sbjct: 121  KVLNSGNFYFAWSASGISLDLSLNAHRSMQEQTTDNRFFWNQSLHLHLKHYGVNCDDWLL 180

Query: 220  RLMCGGVEIRTIYAAHKQAKACLISRLSCERAGTRFNVRGTNDDGHVANFVETEQVVYLD 279
            RLMCGGVEIRTIYAAHKQAKACLISRLSCERAGTRFNVRGTNDDGHVANFVETEQVVYLD
Sbjct: 181  RLMCGGVEIRTIYAAHKQAKACLISRLSCERAGTRFNVRGTNDDGHVANFVETEQVVYLD 240

Query: 280  DSVSSFIQIRGSVPLFWEQPGLQVGSHRVRMSRGFEANAPAFDRHFRTLKNLYGKQIIVN 339
            DSVSSFIQIRGSVPLFWEQPGLQVGSHRVRMSRGFEANAPAFDRHFRTLKNLYGKQIIVN
Sbjct: 241  DSVSSFIQIRGSVPLFWEQPGLQVGSHRVRMSRGFEANAPAFDRHFRTLKNLYGKQIIVN 300

Query: 340  LLGSKEGEHMLSKAFQSHLKASEHAADIQMVNFDYHQMVKGGKAEKLHSVLKPQVQKFLD 399
            LLGSKEGEHMLSKAFQSHLKASEHAADIQMVNFDYHQMVKGGKAEKLHSVLKPQVQKFLD
Sbjct: 301  LLGSKEGEHMLSKAFQSHLKASEHAADIQMVNFDYHQMVKGGKAEKLHSVLKPQVQKFLD 360

Query: 400  YGFFYFNGSEVQRCQSGTVRTNCLDCLDRTNSVQAFLGLEMLAKQLEALGLAEKPQLVTR 459
            YGFFYFNGSEVQRCQSGTVRTNCLDCLDRTNSVQAFLGLEMLAKQLEALGLAEKPQLVTR
Sbjct: 361  YGFFYFNGSEVQRCQSGTVRTNCLDCLDRTNSVQAFLGLEMLAKQLEALGLAEKPQLVTR 420

Query: 460  FQEVFRSMWSVNGDSISKIYAGTGALEGKAK---LKDGARSVTRTIQNNFFDSSKQEAID 516
            FQEVFRSMWSVNGDSISKIYAGTGALEGKAK   LKDGARSVTRTIQNNFFDSSKQEAID
Sbjct: 421  FQEVFRSMWSVNGDSISKIYAGTGALEGKAKAGKLKDGARSVTRTIQNNFFDSSKQEAID 480

Query: 517  VLLLGNTLNSDLADKARALLTTGSLRVSEQTLQSASSKVLKSMCENFYKYSKPKKIRVCV 576
            VLLLGNTLNSDLADKARALLTTGSLR        ASSKVLKSMCENFYKYSKPKKIRVCV
Sbjct: 481  VLLLGNTLNSDLADKARALLTTGSLR--------ASSKVLKSMCENFYKYSKPKKIRVCV 532

Query: 577  GTWNVNGGKQFRSIAFKNQTLTDWLLDAPKLAGIQEFQDKRSKPTDIFAIGFEEMVELNA 636
            GTWNVNGGKQFRSIAFKNQTLTDWLLDAPKLAGIQEFQDKRSKPTDIFAIGFEEMVELNA
Sbjct: 533  GTWNVNGGKQFRSIAFKNQTLTDWLLDAPKLAGIQEFQDKRSKPTDIFAIGFEEMVELNA 592

Query: 637  GNIVSASTTNQKLWAVELQKTISRDNKYVLLASEQLVGVCLFVFIRPQHAPFIRDVAVDT 696
            GNIVSASTTNQKLWAVELQKTISRDNKYVLLASEQLVGVCLFVFIRPQHAPFIRDVAVDT
Sbjct: 593  GNIVSASTTNQKLWAVELQKTISRDNKYVLLASEQLVGVCLFVFIRPQHAPFIRDVAVDT 652

Query: 697  VKTGMGGATGNKGAVAIRMLFHTTSLCFVCSHFAAGQSQVKERNEDFIEIARKLSFPMGR 756
            VKTGMGGATGNKGAVAIRMLFHTTSLCFVCSHFAAGQSQVKERNEDFIEIARKLSFPMGR
Sbjct: 653  VKTGMGGATGNKGAVAIRMLFHTTSLCFVCSHFAAGQSQVKERNEDFIEIARKLSFPMGR 712

Query: 757  MLFSHDYVFWCGDFNYRIDLPNEEVKELIRQQNWDSLIAGDQLINQKNAGQVFRGFLEGK 816
            MLFSHDYVFWCGDFNYRIDLPNEEVKELIRQQNWDSLIAGDQLINQKNAGQVFRGFLEGK
Sbjct: 713  MLFSHDYVFWCGDFNYRIDLPNEEVKELIRQQNWDSLIAGDQLINQKNAGQVFRGFLEGK 772

Query: 817  VTFAPTYKYDLFSDDYDTSEKCRTPAWTDRVLWRRRKWPFDRSAEDLDLLNASFQDESKI 876
            VTFAPTYKYDLFSDDYDTSEKCRTPAWTDRVLWRRRKWPFDRSAEDLDLLNASFQDESKI
Sbjct: 773  VTFAPTYKYDLFSDDYDTSEKCRTPAWTDRVLWRRRKWPFDRSAEDLDLLNASFQDESKI 832

Query: 877  LYTWTPGTLLHYGRAELKTSDHRPVVALIDIDIFEVEAEERQNIYKEVIAVQGPPDGTVL 936
            LYTWTPGTLLHYGRAELKTSDHRPVVALIDIDIFEVEAEERQNIYKEVIAVQGPPDGTVL
Sbjct: 833  LYTWTPGTLLHYGRAELKTSDHRPVVALIDIDIFEVEAEERQNIYKEVIAVQGPPDGTVL 892

Query: 937  VSIKSSLPENNFFDDALIDELLQQFASFGEVILIRFVEDKMWVTFLEGSSALNVLSLNGK 996
            VSIKSSLPENNFFDDALIDELLQQFASFGEVILIRFVEDKMWVTFLEGSSALNVLSLNGK
Sbjct: 893  VSIKSSLPENNFFDDALIDELLQQFASFGEVILIRFVEDKMWVTFLEGSSALNVLSLNGK 952

Query: 997  ELLNRTITIALKSPDWIKNLEEEMSLEKISIALPSSTSSTLLGEDAEVAADFDMEGDVDD 1056
            ELLNRTITIALKSPDWIKNLEEEMSLEKISIALPSSTSSTLLGEDAEVAADFDMEGDVDD
Sbjct: 953  ELLNRTITIALKSPDWIKNLEEEMSLEKISIALPSSTSSTLLGEDAEVAADFDMEGDVDD 1012

Query: 1057 YSAEVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPG 1116
            YSAEVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPG
Sbjct: 1013 YSAEVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPG 1072

Query: 1117 PPSAQSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAP 1176
            PPSAQSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSG   P+P
Sbjct: 1073 PPSAQSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGRSQPSP 1132

Query: 1177 TRKEFGGIGAPPSPGVARREMEAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAGYSTARPT 1236
                                                      QAGLAGPGPAGYSTARPT
Sbjct: 1133 ------------------------------------------QAGLAGPGPAGYSTARPT 1150

Query: 1237 IPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPA 1296
            IPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPA
Sbjct: 1151 IPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPA 1210

Query: 1297 QRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQVKTNGISDGKRE 1356
            QRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQVKTNGISDGKRE
Sbjct: 1211 QRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQVKTNGISDGKRE 1270

Query: 1357 SPLKIDPFEDLSFNLLAVSKAQLSVQTSPVPTPDPKRLIQLPSATQSNVLSSVSCMPTMP 1416
            SPLKIDPFEDLSFNLLAVSKAQLSVQTSPVPTPDPKRLIQLPSATQSNVLSSVSCMPTMP
Sbjct: 1271 SPLKIDPFEDLSFNLLAVSKAQLSVQTSPVPTPDPKRLIQLPSATQSNVLSSVSCMPTMP 1330

Query: 1417 PIPARSQSQENMRSSPNPFITGLTRTNPFSDRTAAPGNPFRAKSEESEATSWFSKEEPVT 1476
            PIPARSQSQENMRSSPNPFITGLTRTNPFSDRTAAPGNPFRAKSEESEATSWFSKEEPVT
Sbjct: 1331 PIPARSQSQENMRSSPNPFITGLTRTNPFSDRTAAPGNPFRAKSEESEATSWFSKEEPVT 1390

Query: 1477 ISPFPSLQPLGHNKSRASSSLDGFKDSFDLQGQSTLKISNPKGWVTFEEEEDFGVKGKSK 1536
            ISPFPSLQPLGHNKSRASSSLDGFKDSFDLQGQSTLKISNPKGWVTFEEEEDFGVKGKSK
Sbjct: 1391 ISPFPSLQPLGHNKSRASSSLDGFKDSFDLQGQSTLKISNPKGWVTFEEEEDFGVKGKSK 1450

Query: 1537 SACSDLLGNQPSSFSGSNLTLNDDWNKGTNVSFCVLPSRRPPPPPVPLLPPGTSPPVDPF 1596
            SACSDLLGNQPSSFSGSNLTLNDDWNKGTNVSFCVLPSRRPPPPPVPLLPPGTSPPVDPF
Sbjct: 1451 SACSDLLGNQPSSFSGSNLTLNDDWNKGTNVSFCVLPSRRPPPPPVPLLPPGTSPPVDPF 1510

Query: 1597 TTLASKASPTLDFTER 1612
            TTLASKASPTLDFTER
Sbjct: 1511 TTLASKASPTLDFTER 1526


>gi|237757308 synaptojanin 1 isoform b [Homo sapiens]
          Length = 1350

 Score = 2703 bits (7006), Expect = 0.0
 Identities = 1344/1344 (100%), Positives = 1344/1344 (100%)

Query: 1    MRKRWACWSGSDAPGGCGGGCGRRRRRSRRKRAASEERRMAFSKGFRIYHKLDPPPFSLI 60
            MRKRWACWSGSDAPGGCGGGCGRRRRRSRRKRAASEERRMAFSKGFRIYHKLDPPPFSLI
Sbjct: 1    MRKRWACWSGSDAPGGCGGGCGRRRRRSRRKRAASEERRMAFSKGFRIYHKLDPPPFSLI 60

Query: 61   VETRHKEECLMFESGAVAVLSSAEKEAIKGTYSKVLDAYGLLGVLRLNLGDTMLHYLVLV 120
            VETRHKEECLMFESGAVAVLSSAEKEAIKGTYSKVLDAYGLLGVLRLNLGDTMLHYLVLV
Sbjct: 61   VETRHKEECLMFESGAVAVLSSAEKEAIKGTYSKVLDAYGLLGVLRLNLGDTMLHYLVLV 120

Query: 121  TGCMSVGKIQESEVFRVTSTEFISLRIDSSDEDRISEVRKVLNSGNFYFAWSASGISLDL 180
            TGCMSVGKIQESEVFRVTSTEFISLRIDSSDEDRISEVRKVLNSGNFYFAWSASGISLDL
Sbjct: 121  TGCMSVGKIQESEVFRVTSTEFISLRIDSSDEDRISEVRKVLNSGNFYFAWSASGISLDL 180

Query: 181  SLNAHRSMQEQTTDNRFFWNQSLHLHLKHYGVNCDDWLLRLMCGGVEIRTIYAAHKQAKA 240
            SLNAHRSMQEQTTDNRFFWNQSLHLHLKHYGVNCDDWLLRLMCGGVEIRTIYAAHKQAKA
Sbjct: 181  SLNAHRSMQEQTTDNRFFWNQSLHLHLKHYGVNCDDWLLRLMCGGVEIRTIYAAHKQAKA 240

Query: 241  CLISRLSCERAGTRFNVRGTNDDGHVANFVETEQVVYLDDSVSSFIQIRGSVPLFWEQPG 300
            CLISRLSCERAGTRFNVRGTNDDGHVANFVETEQVVYLDDSVSSFIQIRGSVPLFWEQPG
Sbjct: 241  CLISRLSCERAGTRFNVRGTNDDGHVANFVETEQVVYLDDSVSSFIQIRGSVPLFWEQPG 300

Query: 301  LQVGSHRVRMSRGFEANAPAFDRHFRTLKNLYGKQIIVNLLGSKEGEHMLSKAFQSHLKA 360
            LQVGSHRVRMSRGFEANAPAFDRHFRTLKNLYGKQIIVNLLGSKEGEHMLSKAFQSHLKA
Sbjct: 301  LQVGSHRVRMSRGFEANAPAFDRHFRTLKNLYGKQIIVNLLGSKEGEHMLSKAFQSHLKA 360

Query: 361  SEHAADIQMVNFDYHQMVKGGKAEKLHSVLKPQVQKFLDYGFFYFNGSEVQRCQSGTVRT 420
            SEHAADIQMVNFDYHQMVKGGKAEKLHSVLKPQVQKFLDYGFFYFNGSEVQRCQSGTVRT
Sbjct: 361  SEHAADIQMVNFDYHQMVKGGKAEKLHSVLKPQVQKFLDYGFFYFNGSEVQRCQSGTVRT 420

Query: 421  NCLDCLDRTNSVQAFLGLEMLAKQLEALGLAEKPQLVTRFQEVFRSMWSVNGDSISKIYA 480
            NCLDCLDRTNSVQAFLGLEMLAKQLEALGLAEKPQLVTRFQEVFRSMWSVNGDSISKIYA
Sbjct: 421  NCLDCLDRTNSVQAFLGLEMLAKQLEALGLAEKPQLVTRFQEVFRSMWSVNGDSISKIYA 480

Query: 481  GTGALEGKAKLKDGARSVTRTIQNNFFDSSKQEAIDVLLLGNTLNSDLADKARALLTTGS 540
            GTGALEGKAKLKDGARSVTRTIQNNFFDSSKQEAIDVLLLGNTLNSDLADKARALLTTGS
Sbjct: 481  GTGALEGKAKLKDGARSVTRTIQNNFFDSSKQEAIDVLLLGNTLNSDLADKARALLTTGS 540

Query: 541  LRVSEQTLQSASSKVLKSMCENFYKYSKPKKIRVCVGTWNVNGGKQFRSIAFKNQTLTDW 600
            LRVSEQTLQSASSKVLKSMCENFYKYSKPKKIRVCVGTWNVNGGKQFRSIAFKNQTLTDW
Sbjct: 541  LRVSEQTLQSASSKVLKSMCENFYKYSKPKKIRVCVGTWNVNGGKQFRSIAFKNQTLTDW 600

Query: 601  LLDAPKLAGIQEFQDKRSKPTDIFAIGFEEMVELNAGNIVSASTTNQKLWAVELQKTISR 660
            LLDAPKLAGIQEFQDKRSKPTDIFAIGFEEMVELNAGNIVSASTTNQKLWAVELQKTISR
Sbjct: 601  LLDAPKLAGIQEFQDKRSKPTDIFAIGFEEMVELNAGNIVSASTTNQKLWAVELQKTISR 660

Query: 661  DNKYVLLASEQLVGVCLFVFIRPQHAPFIRDVAVDTVKTGMGGATGNKGAVAIRMLFHTT 720
            DNKYVLLASEQLVGVCLFVFIRPQHAPFIRDVAVDTVKTGMGGATGNKGAVAIRMLFHTT
Sbjct: 661  DNKYVLLASEQLVGVCLFVFIRPQHAPFIRDVAVDTVKTGMGGATGNKGAVAIRMLFHTT 720

Query: 721  SLCFVCSHFAAGQSQVKERNEDFIEIARKLSFPMGRMLFSHDYVFWCGDFNYRIDLPNEE 780
            SLCFVCSHFAAGQSQVKERNEDFIEIARKLSFPMGRMLFSHDYVFWCGDFNYRIDLPNEE
Sbjct: 721  SLCFVCSHFAAGQSQVKERNEDFIEIARKLSFPMGRMLFSHDYVFWCGDFNYRIDLPNEE 780

Query: 781  VKELIRQQNWDSLIAGDQLINQKNAGQVFRGFLEGKVTFAPTYKYDLFSDDYDTSEKCRT 840
            VKELIRQQNWDSLIAGDQLINQKNAGQVFRGFLEGKVTFAPTYKYDLFSDDYDTSEKCRT
Sbjct: 781  VKELIRQQNWDSLIAGDQLINQKNAGQVFRGFLEGKVTFAPTYKYDLFSDDYDTSEKCRT 840

Query: 841  PAWTDRVLWRRRKWPFDRSAEDLDLLNASFQDESKILYTWTPGTLLHYGRAELKTSDHRP 900
            PAWTDRVLWRRRKWPFDRSAEDLDLLNASFQDESKILYTWTPGTLLHYGRAELKTSDHRP
Sbjct: 841  PAWTDRVLWRRRKWPFDRSAEDLDLLNASFQDESKILYTWTPGTLLHYGRAELKTSDHRP 900

Query: 901  VVALIDIDIFEVEAEERQNIYKEVIAVQGPPDGTVLVSIKSSLPENNFFDDALIDELLQQ 960
            VVALIDIDIFEVEAEERQNIYKEVIAVQGPPDGTVLVSIKSSLPENNFFDDALIDELLQQ
Sbjct: 901  VVALIDIDIFEVEAEERQNIYKEVIAVQGPPDGTVLVSIKSSLPENNFFDDALIDELLQQ 960

Query: 961  FASFGEVILIRFVEDKMWVTFLEGSSALNVLSLNGKELLNRTITIALKSPDWIKNLEEEM 1020
            FASFGEVILIRFVEDKMWVTFLEGSSALNVLSLNGKELLNRTITIALKSPDWIKNLEEEM
Sbjct: 961  FASFGEVILIRFVEDKMWVTFLEGSSALNVLSLNGKELLNRTITIALKSPDWIKNLEEEM 1020

Query: 1021 SLEKISIALPSSTSSTLLGEDAEVAADFDMEGDVDDYSAEVEELLPQHLQPSSSSGLGTS 1080
            SLEKISIALPSSTSSTLLGEDAEVAADFDMEGDVDDYSAEVEELLPQHLQPSSSSGLGTS
Sbjct: 1021 SLEKISIALPSSTSSTLLGEDAEVAADFDMEGDVDDYSAEVEELLPQHLQPSSSSGLGTS 1080

Query: 1081 PSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQPATPLPQKDPAQ 1140
            PSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQPATPLPQKDPAQ
Sbjct: 1081 PSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQPATPLPQKDPAQ 1140

Query: 1141 PLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRKEFGGIGAPPSPGVARREMEAP 1200
            PLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRKEFGGIGAPPSPGVARREMEAP
Sbjct: 1141 PLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRKEFGGIGAPPSPGVARREMEAP 1200

Query: 1201 KSPGTTRKDNIGRSQPSPQAGLAGPGPAGYSTARPTIPPRAGVISAPQSHARASAGRLTP 1260
            KSPGTTRKDNIGRSQPSPQAGLAGPGPAGYSTARPTIPPRAGVISAPQSHARASAGRLTP
Sbjct: 1201 KSPGTTRKDNIGRSQPSPQAGLAGPGPAGYSTARPTIPPRAGVISAPQSHARASAGRLTP 1260

Query: 1261 ESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQEPLVPVAAPMPQSGPQPNLE 1320
            ESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQEPLVPVAAPMPQSGPQPNLE
Sbjct: 1261 ESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQEPLVPVAAPMPQSGPQPNLE 1320

Query: 1321 TPPQPPPRSRSSHSLPSEASSQPQ 1344
            TPPQPPPRSRSSHSLPSEASSQPQ
Sbjct: 1321 TPPQPPPRSRSSHSLPSEASSQPQ 1344


>gi|237757312 synaptojanin 1 isoform c [Homo sapiens]
          Length = 1295

 Score = 2575 bits (6674), Expect = 0.0
 Identities = 1289/1305 (98%), Positives = 1289/1305 (98%), Gaps = 16/1305 (1%)

Query: 40   MAFSKGFRIYHKLDPPPFSLIVETRHKEECLMFESGAVAVLSSAEKEAIKGTYSKVLDAY 99
            MAFSKGFRIYHKLDPPPFSLIVETRHKEECLMFESGAVAVLSSAEKEAIKGTYSKVLDAY
Sbjct: 1    MAFSKGFRIYHKLDPPPFSLIVETRHKEECLMFESGAVAVLSSAEKEAIKGTYSKVLDAY 60

Query: 100  GLLGVLRLNLGDTMLHYLVLVTGCMSVGKIQESEVFRVTSTEFISLRIDSSDEDRISEVR 159
            GLLGVLRLNLGDTMLHYLVLVTGCMSVGKIQESEVFRVTSTEFISLRIDSSDEDRISEVR
Sbjct: 61   GLLGVLRLNLGDTMLHYLVLVTGCMSVGKIQESEVFRVTSTEFISLRIDSSDEDRISEVR 120

Query: 160  KVLNSGNFYFAWSASGISLDLSLNAHRSMQEQTTDNRFFWNQSLHLHLKHYGVNCDDWLL 219
            KVLNSGNFYFAWSASGISLDLSLNAHRSMQEQTTDNRFFWNQSLHLHLKHYGVNCDDWLL
Sbjct: 121  KVLNSGNFYFAWSASGISLDLSLNAHRSMQEQTTDNRFFWNQSLHLHLKHYGVNCDDWLL 180

Query: 220  RLMCGGVEIRTIYAAHKQAKACLISRLSCERAGTRFNVRGTNDDGHVANFVETEQVVYLD 279
            RLMCGGVEIRTIYAAHKQAKACLISRLSCERAGTRFNVRGTNDDGHVANFVETEQVVYLD
Sbjct: 181  RLMCGGVEIRTIYAAHKQAKACLISRLSCERAGTRFNVRGTNDDGHVANFVETEQVVYLD 240

Query: 280  DSVSSFIQIRGSVPLFWEQPGLQVGSHRVRMSRGFEANAPAFDRHFRTLKNLYGKQIIVN 339
            DSVSSFIQIRGSVPLFWEQPGLQVGSHRVRMSRGFEANAPAFDRHFRTLKNLYGKQIIVN
Sbjct: 241  DSVSSFIQIRGSVPLFWEQPGLQVGSHRVRMSRGFEANAPAFDRHFRTLKNLYGKQIIVN 300

Query: 340  LLGSKEGEHMLSKAFQSHLKASEHAADIQMVNFDYHQMVKGGKAEKLHSVLKPQVQKFLD 399
            LLGSKEGEHMLSKAFQSHLKASEHAADIQMVNFDYHQMVKGGKAEKLHSVLKPQVQKFLD
Sbjct: 301  LLGSKEGEHMLSKAFQSHLKASEHAADIQMVNFDYHQMVKGGKAEKLHSVLKPQVQKFLD 360

Query: 400  YGFFYFNGSEVQRCQSGTVRTNCLDCLDRTNSVQAFLGLEMLAKQLEALGLAEKPQLVTR 459
            YGFFYFNGSEVQRCQSGTVRTNCLDCLDRTNSVQAFLGLEMLAKQLEALGLAEKPQLVTR
Sbjct: 361  YGFFYFNGSEVQRCQSGTVRTNCLDCLDRTNSVQAFLGLEMLAKQLEALGLAEKPQLVTR 420

Query: 460  FQEVFRSMWSVNGDSISKIYAGTGALEGKAKLKDGARSVTRTIQNNFFDSSKQEAIDVLL 519
            FQEVFRSMWSVNGDSISKIYAGTGALEGKAKLKDGARSVTRTIQNNFFDSSKQEAIDVLL
Sbjct: 421  FQEVFRSMWSVNGDSISKIYAGTGALEGKAKLKDGARSVTRTIQNNFFDSSKQEAIDVLL 480

Query: 520  LGNTLNSDLADKARALLTTGSLRVSEQTLQSASSKVLKSMCENFYKYSKPKKIRVCVGTW 579
            LGNTLNSDLADKARALLTTGSLRVSEQTLQSASSKVLKSMCENFYKYSKPKKIRVCVGTW
Sbjct: 481  LGNTLNSDLADKARALLTTGSLRVSEQTLQSASSKVLKSMCENFYKYSKPKKIRVCVGTW 540

Query: 580  NVNGGKQFRSIAFKNQTLTDWLLDAPKLAGIQEFQDKRSKPTDIFAIGFEEMVELNAGNI 639
            NVNGGKQFRSIAFKNQTLTDWLLDAPKLAGIQEFQDKRSKPTDIFAIGFEEMVELNAGNI
Sbjct: 541  NVNGGKQFRSIAFKNQTLTDWLLDAPKLAGIQEFQDKRSKPTDIFAIGFEEMVELNAGNI 600

Query: 640  VSASTTNQKLWAVELQKTISRDNKYVLLASEQLVGVCLFVFIRPQHAPFIRDVAVDTVKT 699
            VSASTTNQKLWAVELQKTISRDNKYVLLASEQLVGVCLFVFIRPQHAPFIRDVAVDTVKT
Sbjct: 601  VSASTTNQKLWAVELQKTISRDNKYVLLASEQLVGVCLFVFIRPQHAPFIRDVAVDTVKT 660

Query: 700  GMGGATGNKGAVAIRMLFHTTSLCFVCSHFAAGQSQVKERNEDFIEIARKLSFPMGRMLF 759
            GMGGATGNKGAVAIRMLFHTTSLCFVCSHFAAGQSQVKERNEDFIEIARKLSFPMGRMLF
Sbjct: 661  GMGGATGNKGAVAIRMLFHTTSLCFVCSHFAAGQSQVKERNEDFIEIARKLSFPMGRMLF 720

Query: 760  SHDYVFWCGDFNYRIDLPNEEVKELIRQQNWDSLIAGDQLINQKNAGQVFRGFLEGKVTF 819
            SHDYVFWCGDFNYRIDLPNEEVKELIRQQNWDSLIAGDQLINQKNAGQVFRGFLEGKVTF
Sbjct: 721  SHDYVFWCGDFNYRIDLPNEEVKELIRQQNWDSLIAGDQLINQKNAGQVFRGFLEGKVTF 780

Query: 820  APTYKYDLFSDDYDTSEKCRTPAWTDRVLWRRRKWPFDRSAEDLDLLNASFQDESKILYT 879
            APTYKYDLFSDDYDTSEKCRTPAWTDRVLWRRRKWPFDRSAEDLDLLNASFQDESKILYT
Sbjct: 781  APTYKYDLFSDDYDTSEKCRTPAWTDRVLWRRRKWPFDRSAEDLDLLNASFQDESKILYT 840

Query: 880  WTPGTLLHYGRAELKTSDHRPVVALIDIDIFEVEAEERQNIYKEVIAVQGPPDGTVLVSI 939
            WTPGTLLHYGRAELKTSDHRPVVALIDIDIFEVEAEERQNIYKEVIAVQGPPDGTVLVSI
Sbjct: 841  WTPGTLLHYGRAELKTSDHRPVVALIDIDIFEVEAEERQNIYKEVIAVQGPPDGTVLVSI 900

Query: 940  KSSLPENNFFDDALIDELLQQFASFGEVILIRFVEDKMWVTFLEGSSALNVLSLNGKELL 999
            KSSLPENNFFDDALIDELLQQFASFGEVILIRFVEDKMWVTFLEGSSALNVLSLNGKELL
Sbjct: 901  KSSLPENNFFDDALIDELLQQFASFGEVILIRFVEDKMWVTFLEGSSALNVLSLNGKELL 960

Query: 1000 NRTITIALKSPDWIKNLEEEMSLEKISIALPSSTSSTLLGEDAEVAADFDMEGDVDDYSA 1059
            NRTITIALKSPDWIKNLEEEMSLEKISIALPSSTSSTLLGEDAEVAADFDMEGDVDDYSA
Sbjct: 961  NRTITIALKSPDWIKNLEEEMSLEKISIALPSSTSSTLLGEDAEVAADFDMEGDVDDYSA 1020

Query: 1060 EVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPS 1119
            EVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPS
Sbjct: 1021 EVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPS 1080

Query: 1120 AQSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRK 1179
            AQSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRK
Sbjct: 1081 AQSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRK 1140

Query: 1180 EFGGIGAPPSPGVARREMEAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAGYSTARPTIPP 1239
            EFG                APKSPGTTRKDNIGRSQPSPQAGLAGPGPAGYSTARPTIPP
Sbjct: 1141 EFG----------------APKSPGTTRKDNIGRSQPSPQAGLAGPGPAGYSTARPTIPP 1184

Query: 1240 RAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRL 1299
            RAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRL
Sbjct: 1185 RAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRL 1244

Query: 1300 QEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQ 1344
            QEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQ
Sbjct: 1245 QEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQ 1289


>gi|26190608 synaptojanin 2 [Homo sapiens]
          Length = 1496

 Score = 1174 bits (3036), Expect = 0.0
 Identities = 628/1343 (46%), Positives = 873/1343 (65%), Gaps = 69/1343 (5%)

Query: 40   MAFSKGFRIYHKLDPP-PFSLIVETRHKEECLMFESGAVAVLSSAEKEAIKGTYSKVLDA 98
            MA SKG R+  +L      S+++E R +++CL+FE+G VA L+  EKE IKG Y K+ DA
Sbjct: 1    MALSKGLRLLGRLGAEGDCSVLLEARGRDDCLLFEAGTVATLAPEEKEVIKGQYGKLTDA 60

Query: 99   YGLLGVLRLNLGDTMLHYLVLVTGCMSVGKIQESEVFRVTSTEFISLRIDSSDEDRISEV 158
            YG LG LRL  G T L +LVLVTGC SVG+I ++E++++T+T+F  L+ ++ +E+R+  +
Sbjct: 61   YGCLGELRLKSGGTSLSFLVLVTGCTSVGRIPDAEIYKITATDFYPLQEEAKEEERLIAL 120

Query: 159  RKVLNSGNFYFAWSASGISLDLSLNAHRSMQEQTT-DNRFFWNQSLHLHLKHYGVNCDDW 217
            +K+L+SG FYF+W   G   DL++   +   + +   N FFWNQ LH+ L+ + V+C DW
Sbjct: 121  KKILSSGVFYFSWPNDGSRFDLTVRTQKQGDDSSEWGNSFFWNQLLHVPLRQHQVSCCDW 180

Query: 218  LLRLMCGGVEIRTIYAAHKQAKACLISRLSCERAGTRFNVRGTNDDGHVANFVETEQVVY 277
            LL+++CG V IRT+YA+HKQAKACL+SR+SCER GTRF+ RG NDDGHV+NFVETEQ++Y
Sbjct: 181  LLKIICGVVTIRTVYASHKQAKACLVSRVSCERTGTRFHTRGVNDDGHVSNFVETEQMIY 240

Query: 278  LDDSVSSFIQIRGSVPLFWEQPGLQVGSHRVRMSRGFEANAPAFDRHFRTLKNLYGKQII 337
            +DD VSSF+QIRGSVPLFWEQPGLQVGSH +R+ RG EANAPAFDRH   LK  YG+Q++
Sbjct: 241  MDDGVSSFVQIRGSVPLFWEQPGLQVGSHHLRLHRGLEANAPAFDRHMVLLKEQYGQQVV 300

Query: 338  VNLLGSKEGEHMLSKAFQSHLKASEHAADIQMVNFDYHQMVKGGKAEKLHSVLKPQVQ-K 396
            VNLLGS+ GE +L++AF+  L AS HA D  M+NFD+HQ  KGGK EKL ++L+PQ++  
Sbjct: 301  VNLLGSRGGEEVLNRAFKKLLWASCHAGDTPMINFDFHQFAKGGKLEKLETLLRPQLKLH 360

Query: 397  FLDYGFFYFNGSEVQRCQSGTVRTNCLDCLDRTNSVQAFLGLEMLAKQLEALGLAEKPQL 456
            + D+  F    +   R Q GT+R NCLDCLDRTN+VQ+F+ LE+L  QL+ LGL+ KP +
Sbjct: 361  WEDFDVFTKGENVSPRFQKGTLRMNCLDCLDRTNTVQSFIALEVLHLQLKTLGLSSKP-I 419

Query: 457  VTRFQEVFRSMWSVNGDSISKIYAGTGALEGKAK---LKDGARSVTRTIQNNFFDSSKQE 513
            V RF E F++MWS+NG S+SK++ G+ ALEGKAK   LKDGARS++RTIQ+NFFD  KQE
Sbjct: 420  VDRFVESFKAMWSLNGHSLSKVFTGSRALEGKAKVGKLKDGARSMSRTIQSNFFDGVKQE 479

Query: 514  AIDVLLLGNTLNSDLADKARALLTTGSLRVSEQTLQSASSKVLKSMCENFYKYSKPKKIR 573
            AI +LL+G+    ++ADK   LL + +L V+         ++LK+M E   +++  K+IR
Sbjct: 480  AIKLLLVGDVYGEEVADKGGMLLDSTALLVTP--------RILKAMTERQSEFTNFKRIR 531

Query: 574  VCVGTWNVNGGKQFRSIAFKNQTLTDWLLDAPKLAGIQEFQDKRSKPTDIFAIGFEEMVE 633
            + +GTWNVNGGKQFRS   +   LTDWLLD+P+L+G  + QD  S P DIFA+GFEEMVE
Sbjct: 532  IAMGTWNVNGGKQFRSNVLRTAELTDWLLDSPQLSGATDSQDD-SSPADIFAVGFEEMVE 590

Query: 634  LNAGNIVSASTTNQKLWAVELQKTISRDNKYVLLASEQLVGVCLFVFIRPQHAPFIRDVA 693
            L+AGNIV+ASTTN+K+W  +LQK ISR ++Y+LL S QLVGVCL++F+RP H PFIRDVA
Sbjct: 591  LSAGNIVNASTTNKKMWGEQLQKAISRSHRYILLTSAQLVGVCLYIFVRPYHVPFIRDVA 650

Query: 694  VDTVKTGMGGATGNKGAVAIRMLFHTTSLCFVCSHFAAGQSQVKERNEDFIEIARKLSFP 753
            +DTVKTGMGG  GNKGAV IR  FH+TS CF+CSH  AGQSQVKERNED+ EI +KL FP
Sbjct: 651  IDTVKTGMGGKAGNKGAVGIRFQFHSTSFCFICSHLTAGQSQVKERNEDYKEITQKLCFP 710

Query: 754  MGRMLFSHDYVFWCGDFNYRIDLPNEEVKELIRQQNWDSLIAGDQLINQKNAGQVFRGFL 813
            MGR +FSHDYVFWCGDFNYRIDL  EEV   +++Q+W  L+  DQL  QK++G++F+ F 
Sbjct: 711  MGRNVFSHDYVFWCGDFNYRIDLTYEEVFYFVKRQDWKKLLEFDQLQLQKSSGKIFKDFH 770

Query: 814  EGKVTFAPTYKYDLFSDDYDTSEKCRTPAWTDRVLWRRRKWPFDRSAEDLDLLNASFQDE 873
            EG + F PTYKYD+ S  YDTS+KCRTPAWTDRVLW R+K PFD++A +L+LL++    +
Sbjct: 771  EGAINFGPTYKYDVGSAAYDTSDKCRTPAWTDRVLWWRKKHPFDKTAGELNLLDSDLDVD 830

Query: 874  SKILYTWTPGTLLHYGRAELKTSDHRPVVALIDIDIFEVEAEERQNIYKEVIAVQGPPDG 933
            +K+ +TW+PG L +YGRAEL+ SDHRPV+A++++++ EV+   R+ +++EV + QGP D 
Sbjct: 831  TKVRHTWSPGALQYYGRAELQASDHRPVLAIVEVEVQEVDVGARERVFQEVSSFQGPLDA 890

Query: 934  TVLVSIKS-SLPENNFFDDALIDELLQQFASFGEVILIRFVEDKMWVTFLEGSSALNVLS 992
            TV+V+++S +L E N F + L  EL+Q   S+G ++L+R  + +M VTF +  SAL+VL 
Sbjct: 891  TVVVNLQSPTLEEKNEFPEDLRTELMQTLGSYGTIVLVRINQGQMLVTFADSHSALSVLD 950

Query: 993  LNGKELLNRTITIALKSPDWIKNLEEEMSLEKISIALPSSTSSTLLGEDAEVAADFDMEG 1052
            ++G ++  R + I  K+ DW+K L EE+  ++ S+A  S T+++ L E+       D E 
Sbjct: 951  VDGMKVKGRAVKIRPKTKDWLKGLREEIIRKRDSMAPVSPTANSCLLEENFDFTSLDYES 1010

Query: 1053 DVDDYSAEVEELLPQHLQPS-SSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAP 1111
            + D    + + L+ +  QP  S S LG                +S+ P P+    PS++P
Sbjct: 1011 EGDILEDDEDYLVDEFNQPGVSDSELG-------------GDDLSDVPGPTALAPPSKSP 1057

Query: 1112 SRTPGPPSAQSSPIDAQPATPLPQKDPAQPL-EPKRPPPPRPVAPPTR---PAPPQRPPP 1167
            + T      +  P     A  +  K   + + E +   P R ++ P R   P PPQRPPP
Sbjct: 1058 ALT----KKKQHPTYKDDADLVELKRELEAVGEFRHRSPSRSLSVPNRPRPPQPPQRPPP 1113

Query: 1168 PSG---------ARSPAPTRKEFGGI-------GAPPSPGVARREMEAPKSPGTTRKDNI 1211
            P+G         A   + T  ++  +       GAP  P  AR  +  P +    +  N 
Sbjct: 1114 PTGLMVKKSASDASISSGTHGQYSILQTARLLPGAPQQPPKARTGISKPYNVKQIKTTNA 1173

Query: 1212 GRSQPSPQAGLAGPGPAGYSTARPTIPPRAGVISAPQSHARAS------AGRLTPESQSK 1265
              ++ + +  L   G A         P      S P+    A+      A  L P     
Sbjct: 1174 QEAEAAIRCLLEARGGASEEALSAVAPRDLEASSEPEPTPGAAKPETPQAPPLLPRRPPP 1233

Query: 1266 TSETSKGSTF--LPEPLKPQAAFPPQS---SLPPPAQRLQEPLVPVAAPMPQSGPQPNLE 1320
                 K  T     +PL P+  F  Q+   ++ PP   ++ P V  A  +P   P P   
Sbjct: 1234 RVPAIKKPTLRRTGKPLSPEEQFEQQTVHFTIGPPETSVEAPPVVTAPRVP---PVPKPR 1290

Query: 1321 TPPQPPPRSRSSHSLPSEASSQP 1343
            T        R SH  P+   + P
Sbjct: 1291 TFQPGKAAERPSHRKPASDEAPP 1313



 Score = 35.0 bits (79), Expect = 0.59
 Identities = 47/200 (23%), Positives = 66/200 (33%), Gaps = 47/200 (23%)

Query: 1085 PRTSPCQSPTISEGPVPSLP----IRPSRAPSR-TPGPPSAQSSPIDAQPATPLPQKDPA 1139
            P TS    P ++   VP +P     +P +A  R +   P++  +P  A  + P P + P 
Sbjct: 1268 PETSVEAPPVVTAPRVPPVPKPRTFQPGKAAERPSHRKPASDEAPPGAGASVPPPLEAP- 1326

Query: 1140 QPLEPKRPPPPRPVAPPT-------------------RPAPPQRPPPPSGARSPAPTRKE 1180
             PL PK PP  +  AP                         P   PP +G   P      
Sbjct: 1327 -PLVPKVPPRRKKSAPAAFHLQVLQSNSQLLQGLTYNSSDSPSGHPPAAGTVFPQGDFLS 1385

Query: 1181 FGGIGAPPSPGVARREMEA-----------------PKSPGTT----RKDNIGRSQPSPQ 1219
                 +P S G    + EA                 PK    T      D +     SP+
Sbjct: 1386 TSSATSPDSDGTKAMKPEAAPLLGDYQDPFWNLLHHPKLLNNTWLSKSSDPLDSGTRSPK 1445

Query: 1220 AGLAGPGPAGYSTARPTIPP 1239
                 P  AG S A+  +PP
Sbjct: 1446 RDPIDPVSAGASAAKAELPP 1465



 Score = 32.3 bits (72), Expect = 3.8
 Identities = 50/240 (20%), Positives = 77/240 (32%), Gaps = 46/240 (19%)

Query: 1036 TLLGEDAEVAADFDMEGDVDDYSAEVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTI 1095
            T   ++AE A    +E         +  + P+ L+ SS      +P ++   +P   P +
Sbjct: 1170 TTNAQEAEAAIRCLLEARGGASEEALSAVAPRDLEASSEPE--PTPGAAKPETPQAPPLL 1227

Query: 1096 SEGPVPSLPIRPSRAPSRTPGPPSAQS---------------SPIDAQPATPLPQKDPA- 1139
               P P +P        RT  P S +                + ++A P    P+  P  
Sbjct: 1228 PRRPPPRVPAIKKPTLRRTGKPLSPEEQFEQQTVHFTIGPPETSVEAPPVVTAPRVPPVP 1287

Query: 1140 -----------------QPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRKEFG 1182
                             +P   + PP      PP   APP  P  P       P RK+  
Sbjct: 1288 KPRTFQPGKAAERPSHRKPASDEAPPGAGASVPPPLEAPPLVPKVP-------PRRKK-- 1338

Query: 1183 GIGAPPSPGVARREMEAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAGYSTARPTIPPRAG 1242
               AP +  +   +  +    G T   +   S   P AG   P     ST+  T P   G
Sbjct: 1339 --SAPAAFHLQVLQSNSQLLQGLTYNSSDSPSGHPPAAGTVFPQGDFLSTSSATSPDSDG 1396


>gi|113722125 inositol polyphosphate-5-phosphatase, 75kDa precursor
           [Homo sapiens]
          Length = 913

 Score =  211 bits (538), Expect = 4e-54
 Identities = 138/416 (33%), Positives = 214/416 (51%), Gaps = 63/416 (15%)

Query: 522 NTLNSDLADKARALLTTGSLRVSEQTLQSASSK--VLKS-MCENFYKYSKPKKIRVCVGT 578
           N   S++ D  R+   T S +    ++Q    +  ++KS + +    Y+  +  R   GT
Sbjct: 212 NKSKSEITDMVRSSTITVSDKAHILSMQKFGLRDTIVKSHLLQKEEDYTYIQNFRFFAGT 271

Query: 579 WNVNGGKQFRSIAFKNQTLTDWLLDAPKLAGIQEFQDKRSKPTDIFAIGFEEMVELNAGN 638
           +NVNG           + L  WL +     GIQ          D++ +GF+E+ +L+   
Sbjct: 272 YNVNGQSP-------KECLRLWLSN-----GIQA--------PDVYCVGFQEL-DLSKEA 310

Query: 639 IVSASTTNQKLWAVELQKTISRDNKYVLLASEQLVGVCLFVFIRPQHAPFIRDVAVDTVK 698
                T  ++ W   + + +  D KY  +   +LVG+ L ++++ +HA +I +V  +TV 
Sbjct: 311 FFFHDTPKEEEWFKAVSEGLHPDAKYAKVKLIRLVGIMLLLYVKQEHAAYISEVEAETVG 370

Query: 699 TGMGGATGNKGAVAIRMLFHTTSLCFVCSHFAAGQSQVKERNEDFIEIARKLSF------ 752
           TG+ G  GNKG VAIR  FH TS+C V SH AA   + + RN+D+ +I  ++ F      
Sbjct: 371 TGIMGRMGNKGGVAIRFQFHNTSICVVNSHLAAHIEEYERRNQDYKDICSRMQFCQPDPS 430

Query: 753 --PMGRMLFSHDYVFWCGDFNYRID-LPNEEVKELIRQQNWDSLIAGDQLINQKNAGQVF 809
             P+   + +HD + W GD NYRI+ L  E+VK+LI ++++  L A DQL  Q  A  VF
Sbjct: 431 LPPL--TISNHDVILWLGDLNYRIEELDVEKVKKLIEEKDFQMLYAYDQLKIQVAAKTVF 488

Query: 810 RGFLEGKVTFAPTYKYDLFSDDYDTSEKCRTPAWTDRVLWRRRKWPFDRSAEDLDLLNAS 869
            GF EG++TF PTYKYD  SDD+DTSEKCR PAW DR+LW+ +           ++   S
Sbjct: 489 EGFTEGELTFQPTYKYDTGSDDWDTSEKCRAPAWCDRILWKGK-----------NITQLS 537

Query: 870 FQDESKILYTWTPGTLLHYGRAELKTSDHRPVVALIDIDIFEVEAEERQNIYKEVI 925
           +Q                     LKTSDH+PV ++ DI +  V  E  +   +E++
Sbjct: 538 YQ-----------------SHMALKTSDHKPVSSVFDIGVRVVNDELYRKTLEEIV 576


>gi|13325070 phosphatidylinositol polyphosphate 5-phosphatase
           isoform b [Homo sapiens]
          Length = 893

 Score =  206 bits (524), Expect = 1e-52
 Identities = 125/388 (32%), Positives = 194/388 (50%), Gaps = 56/388 (14%)

Query: 565 KYSKPKKIRVCVGTWNVNGGKQFRSIAFKNQTLTDWLLDAPKLAGIQEFQDKRSKPTDIF 624
           +Y   +  R  VGTWNVNG          +  L  WL   P              P DI+
Sbjct: 233 EYVNIQTFRFFVGTWNVNGQSP-------DSGLEPWLNCDPN-------------PPDIY 272

Query: 625 AIGFEEMVELNAGNIVSASTTNQKLWAVELQKTISRDNKYVLLASEQLVGVCLFVFIRPQ 684
            IGF+E+ +L+        +  ++ W++ +++ +    KY  +   +LVG+ L +F R  
Sbjct: 273 CIGFQEL-DLSTEAFFYFESVKEQEWSMAVERGLHSKAKYKKVQLVRLVGMMLLIFARKD 331

Query: 685 HAPFIRDVAVDTVKTGMGGATGNKGAVAIRMLFHTTSLCFVCSHFAAGQSQVKERNEDFI 744
              +IRD+A +TV TG+ G  GNKG VA+R +FH T+ C V SH AA     + RN+D+ 
Sbjct: 332 QCRYIRDIATETVGTGIMGKMGNKGGVAVRFVFHNTTFCIVNSHLAAHVEDFERRNQDYK 391

Query: 745 EIARKLSFPMGRM------LFSHDYVFWCGDFNYRIDLPN-EEVKELIRQQNWDSLIAGD 797
           +I  ++SF +         +  H+ V W GD NYR+ +P+  EVK LI +++   L+  D
Sbjct: 392 DICARMSFVVPNQTLPQLNIMKHEVVIWLGDLNYRLCMPDANEVKSLINKKDLQRLLKFD 451

Query: 798 QLINQKNAGQVFRGFLEGKVTFAPTYKYDLFSDDYDTSEKCRTPAWTDRVLWRRRKWPFD 857
           QL  Q+   + F  F EG++ F PTYKYD  +D +D+S KCR PAW DR+LWR       
Sbjct: 452 QLNIQRTQKKAFVDFNEGEIKFIPTYKYDSKTDRWDSSGKCRVPAWCDRILWR------- 504

Query: 858 RSAEDLDLLNASFQDESKILYTWTPGTLLHYGRAELKTSDHRPVVALIDIDIFEVEAEER 917
               +++ LN                   +    ELKTSDH+PV AL  I +  V+    
Sbjct: 505 --GTNVNQLN-------------------YRSHMELKTSDHKPVSALFHIGVKVVDERRY 543

Query: 918 QNIYKEVIAVQGPPDGTVLVSIKSSLPE 945
           + ++++ + +    +   L S++ S  E
Sbjct: 544 RKVFEDSVRIMDRMENDFLPSLELSRRE 571


>gi|13325072 phosphatidylinositol polyphosphate 5-phosphatase
           isoform a [Homo sapiens]
          Length = 901

 Score =  206 bits (524), Expect = 1e-52
 Identities = 125/388 (32%), Positives = 194/388 (50%), Gaps = 56/388 (14%)

Query: 565 KYSKPKKIRVCVGTWNVNGGKQFRSIAFKNQTLTDWLLDAPKLAGIQEFQDKRSKPTDIF 624
           +Y   +  R  VGTWNVNG          +  L  WL   P              P DI+
Sbjct: 233 EYVNIQTFRFFVGTWNVNGQSP-------DSGLEPWLNCDPN-------------PPDIY 272

Query: 625 AIGFEEMVELNAGNIVSASTTNQKLWAVELQKTISRDNKYVLLASEQLVGVCLFVFIRPQ 684
            IGF+E+ +L+        +  ++ W++ +++ +    KY  +   +LVG+ L +F R  
Sbjct: 273 CIGFQEL-DLSTEAFFYFESVKEQEWSMAVERGLHSKAKYKKVQLVRLVGMMLLIFARKD 331

Query: 685 HAPFIRDVAVDTVKTGMGGATGNKGAVAIRMLFHTTSLCFVCSHFAAGQSQVKERNEDFI 744
              +IRD+A +TV TG+ G  GNKG VA+R +FH T+ C V SH AA     + RN+D+ 
Sbjct: 332 QCRYIRDIATETVGTGIMGKMGNKGGVAVRFVFHNTTFCIVNSHLAAHVEDFERRNQDYK 391

Query: 745 EIARKLSFPMGRM------LFSHDYVFWCGDFNYRIDLPN-EEVKELIRQQNWDSLIAGD 797
           +I  ++SF +         +  H+ V W GD NYR+ +P+  EVK LI +++   L+  D
Sbjct: 392 DICARMSFVVPNQTLPQLNIMKHEVVIWLGDLNYRLCMPDANEVKSLINKKDLQRLLKFD 451

Query: 798 QLINQKNAGQVFRGFLEGKVTFAPTYKYDLFSDDYDTSEKCRTPAWTDRVLWRRRKWPFD 857
           QL  Q+   + F  F EG++ F PTYKYD  +D +D+S KCR PAW DR+LWR       
Sbjct: 452 QLNIQRTQKKAFVDFNEGEIKFIPTYKYDSKTDRWDSSGKCRVPAWCDRILWR------- 504

Query: 858 RSAEDLDLLNASFQDESKILYTWTPGTLLHYGRAELKTSDHRPVVALIDIDIFEVEAEER 917
               +++ LN                   +    ELKTSDH+PV AL  I +  V+    
Sbjct: 505 --GTNVNQLN-------------------YRSHMELKTSDHKPVSALFHIGVKVVDERRY 543

Query: 918 QNIYKEVIAVQGPPDGTVLVSIKSSLPE 945
           + ++++ + +    +   L S++ S  E
Sbjct: 544 RKVFEDSVRIMDRMENDFLPSLELSRRE 571


>gi|190014578 suppressor of actin 1 [Homo sapiens]
          Length = 587

 Score =  203 bits (517), Expect = 1e-51
 Identities = 147/454 (32%), Positives = 237/454 (52%), Gaps = 40/454 (8%)

Query: 99  YGLLGVLRLNLGDTMLHYLVLVTGCMSVGKIQESEVFRVTSTEFISLR------IDSSDE 152
           +G+LG + L  G+    YL+++T  + VG+     V++ T  + +S +       D   +
Sbjct: 58  FGILGTIHLVAGN----YLIVITKKIKVGEFFSHVVWKATDFDVLSYKKTMLHLTDIQLQ 113

Query: 153 DR---ISEVRKVLNSGNFYFAWSASGI-SLDLSLNAHRSMQEQT----TDNRFFWNQSLH 204
           D    ++ +  VLN   FYF+ +     +L    N     QE +     D RF WN  L 
Sbjct: 114 DNKTFLAMLNHVLNVDGFYFSTTYDLTHTLQRLSNTSPEFQEMSLLERADQRFVWNGHLL 173

Query: 205 LHLKHYGVNCDDWLLRLMCGGVEIRTIYAAHKQAKACLISRLSCERAGTRFNVRGTNDDG 264
             L         + L ++ G + + +     K     LISR SC RAG R+ VRG + +G
Sbjct: 174 RELSAQP-EVHRFALPVLHGFITMHSCSINGKYFDWILISRRSCFRAGVRYYVRGIDSEG 232

Query: 265 HVANFVETEQVVYLDDSVSSFIQIRGSVPLFWEQ-PGLQVGSHRVRMSRGFEANAPAFDR 323
           H ANFVETEQ+V+ + S +SF+Q RGS+P+FW Q P L+     +        +   F R
Sbjct: 233 HAANFVETEQIVHYNGSKASFVQTRGSIPVFWSQRPNLKY--KPLPQISKVANHMDGFQR 290

Query: 324 HFRTLKNLYGKQIIVNLLGSKEGEHMLSKAFQSHLKASEHAADIQMVNFDYHQMVKGGKA 383
           HF +   +YGKQ+I+NL+  K  E  L + F + + +S  +  ++ + FD+H+  K  + 
Sbjct: 291 HFDSQVIIYGKQVIINLINQKGSEKPLEQTFAT-MVSSLGSGMMRYIAFDFHKECKNMRW 349

Query: 384 EKLHSVLKPQVQKFLDYGFFYF--NGSEVQRCQSGTVRTNCLDCLDRTNSVQAFLGLEML 441
           ++L S+L  QV +  D   ++   +  +V   Q G  R+NC+DCLDRTN +Q+ L    L
Sbjct: 350 DRL-SILLDQVAEMQDELSYFLVDSAGQVVANQEGVFRSNCMDCLDRTNVIQSLLARRSL 408

Query: 442 AKQLEALG---LAEKPQLVTRFQEVFRSMWSVNGDSISKIYAGTGALE------GK---- 488
             QL+ LG   + +K +    F++++++ W+ N ++ +K YAGTGAL+      GK    
Sbjct: 409 QAQLQRLGVLHVGQKLEEQDEFEKIYKNAWADNANACAKQYAGTGALKTDFTRTGKRTHL 468

Query: 489 AKLKDGARSVTRTIQNNFFDSSKQEAIDVLLLGN 522
             + DG  S+ R  +NNF D  +Q++ID L LGN
Sbjct: 469 GLIMDGWNSMIRYYKNNFSDGFRQDSID-LFLGN 501


>gi|7662414 inositol polyphosphate-5-phosphatase F [Homo sapiens]
          Length = 1132

 Score =  192 bits (487), Expect = 3e-48
 Identities = 129/416 (31%), Positives = 208/416 (50%), Gaps = 53/416 (12%)

Query: 158 VRKVLNSGNFYFAWSASGISLDLSLNAHRSMQE--------QTTDNRFFWNQSLHLHLKH 209
           ++  ++S +FY++     ++ DL+ +  R            Q  D+RFFWN+ +   L  
Sbjct: 167 LKMFMDSESFYYS-----LTYDLTNSVQRQSTGERDGRPLWQKVDDRFFWNKYMIQDLTE 221

Query: 210 YGV-NCDDWLLRLMCGGVEIRTIYA-------------------------AHKQAKACLI 243
            G  + D W++ ++ G V+I  +                            H +    LI
Sbjct: 222 IGTPDVDFWIIPMIQGFVQIEELVVNYTESSDDEKSSPETPPQESTCVDDIHPRFLVALI 281

Query: 244 SRLSCERAGTRFNVRGTNDDGHVANFVETEQVVYLDDSVSSFIQIRGSVPLFWEQPGLQV 303
           SR S  RAG R+  RG + +G+VAN+VETEQ++++ +   SF+Q RGSVP+FW Q G + 
Sbjct: 282 SRRSRHRAGMRYKRRGVDKNGNVANYVETEQLIHVHNHTLSFVQTRGSVPVFWSQVGYRY 341

Query: 304 GSHRVRMSRGFEANAPAFDRHFRTLKNLYGKQIIVNLLGSKEGEHMLSKAFQSHLKASEH 363
            + R R+ R  +     F  HF    N+Y KQ+I+NL+     E ++  A+   +    +
Sbjct: 342 -NPRPRLDRSEKETVAYFCAHFEEQLNIYKKQVIINLVDQAGREKIIGDAYLKQVLLFNN 400

Query: 364 AADIQMVNFDYHQMVKGGKAEKLHSVLKPQVQKFLDYGFFYFNGSEVQRCQSGTVRTNCL 423
            + +  V+FD+H+  +G K E + ++        LD  + + + + V   Q G  R NC+
Sbjct: 401 -SHLTYVSFDFHEHCRGMKFENVQTLTDAIYDIILDMKWCWVDEAGVICKQEGIFRVNCM 459

Query: 424 DCLDRTNSVQAFLGLEMLAKQLEALGLAEKPQ-LVTRFQEVFRSMWSVNGDSISKIYAGT 482
           DCLDRTN VQA +   ++ +QL+ LG+    Q L  +   +++ MW+ NGDSIS+ YAGT
Sbjct: 460 DCLDRTNVVQAAIARVVMEQQLKKLGVMPPEQPLPVKCNRIYQIMWANNGDSISRQYAGT 519

Query: 483 GALEG----------KAKLKDGARSVTRTIQNNFFDSSKQEAIDVLLLGNTLNSDL 528
            AL+G             +KDG  S  R   N F D+ +Q  ID L+ G  +  DL
Sbjct: 520 AALKGDFTRTGERKLAGVMKDGVNSANRYYLNRFKDAYRQAVID-LMQGIPVTEDL 574


>gi|40254823 SH2 containing inositol phosphatase isoform b [Homo
            sapiens]
          Length = 1188

 Score =  177 bits (450), Expect = 6e-44
 Identities = 205/830 (24%), Positives = 331/830 (39%), Gaps = 141/830 (16%)

Query: 554  KVLKSMCENFYKYSKPKKIRVCVGTWNVNGGKQFRSIAFKNQTLTDWLLDAPKLAGIQEF 613
            ++L+ M     +  +P  I + +GTWN+      + I       T W L   K  G    
Sbjct: 385  QLLQQMKNKHSEQPEPDMITIFIGTWNMGNAPPPKKI-------TSWFLS--KGQGKTRD 435

Query: 614  QDKRSKPTDIFAIGFEEMVELNAGNIVSASTTNQKLWAVELQKTISRDNK--YVLLASEQ 671
                  P DI+ IG +E               ++K W   L+ ++       +  +A   
Sbjct: 436  DSADYIPHDIYVIGTQE------------DPLSEKEWLEILKHSLQEITSVTFKTVAIHT 483

Query: 672  LVGVCLFVFIRPQHAPFIRDVAVDTVKTGMGGATGNKGAVAIRMLFHTTSLCFVCSHFAA 731
            L  + + V  +P+H   I  +  D VKTG+    GNKGAV +  +F+ TSL FV SH  +
Sbjct: 484  LWNIRIVVLAKPEHENRISHICTDNVKTGIANTLGNKGAVGVSFMFNGTSLGFVNSHLTS 543

Query: 732  GQSQVKERNEDFIEIARKLSF---PMGRMLFSH--DYVFWCGDFNYRIDLPN---EEVKE 783
            G  +   RN++++ I R L+     +     +H   ++FW GD NYR+DLP    E + +
Sbjct: 544  GSEKKLRRNQNYMNILRFLALGDKKLSPFNITHRFTHLFWFGDLNYRVDLPTWEAETIIQ 603

Query: 784  LIRQQNWDSLIAGDQLINQKNAGQVFRGFLEGKVTFAPTYKYD-LFSDDY------DTSE 836
             I+QQ +  L++ DQL+ ++   +VF  F E ++TFAPTY+++ L  D Y       T  
Sbjct: 604  KIKQQQYADLLSHDQLLTERREQKVFLHFEEEEITFAPTYRFERLTRDKYAYTKQKATGM 663

Query: 837  KCRTPAWTDRVLWRRRKWPFDRSAEDLDLLNASFQDESKILYTWTPGTLLHYGRAELKTS 896
            K   P+W DRVLW  + +P       + ++  S+   S I+                 TS
Sbjct: 664  KYNLPSWCDRVLW--KSYPL------VHVVCQSYGSTSDIM-----------------TS 698

Query: 897  DHRPVVALIDIDIFEVEAEERQNIYKEVIAVQGPPDGTVLVSIKSSLPENNFFDDALIDE 956
            DH PV A  +  +      +        +  QG  +     +   +  +  F+ +     
Sbjct: 699  DHSPVFATFEAGVTSQFVSKNG---PGTVDSQGQIEFLRCYATLKTKSQTKFYLE-FHSS 754

Query: 957  LLQQFASFGEVILIRFVEDKMWVTFLEGSSALNVLSLNGKELLNRTITIALKSPDWIKNL 1016
             L+ F    E       E ++ V F E    L  +  + + LL++ I I++KS D  ++ 
Sbjct: 755  CLESFVKSQEGENEEGSEGELVVKFGETLPKLKPIISDPEYLLDQHILISIKSSDSDESY 814

Query: 1017 EE---EMSLEKISIALPSSTSSTLLGEDAEVAADFDMEGDVDDYSAEVEELLPQHL--QP 1071
             E    + LE     LP  T  T  G   E+   F  E  +     +  E L   +  + 
Sbjct: 815  GEGCIALRLEATETQLPIYTPLTHHG---ELTGHFQGEIKLQTSQGKTREKLYDFVKTER 871

Query: 1072 SSSSGLGTSPS-----------SSPRTSPCQSPTISE------------GPVPSLPIRPS 1108
              SSG  T  S            + R  PC   +I+E            GP   L ++ +
Sbjct: 872  DESSGPKTLKSLTSHDPMKQWEVTSRAPPCSGSSITEIINPNYMGVGPFGPPMPLHVKQT 931

Query: 1109 RAPSRTPGPPSAQSSPIDAQPATPLPQKDPAQPLEPKRPP-PPRPVAPPT--RPAPP--Q 1163
             +P + P   S    P D+ P  P   + P  P  P +PP  P+   P T  R  PP  Q
Sbjct: 932  LSPDQQPTAWSYDQPPKDS-PLGPCRGESP--PTPPGQPPISPKKFLPSTANRGLPPRTQ 988

Query: 1164 RPPPPSGARSPAPTRKE---------------FGGIGAPPSPGVARREMEAPKSPGTTRK 1208
               P    ++   T  +               +G + + P P   R++ E+PK P   RK
Sbjct: 989  ESRPSDLGKNAGDTLPQEDLPLTKPEMFENPLYGSLSSFPKP-APRKDQESPKMP---RK 1044

Query: 1209 DNIGRSQPSPQAGLAGP---------GPAGYSTARPTIPPRAGVISAPQSHARASAGRLT 1259
            +      P P+ G+  P            G    +    PR    +   S    +AG   
Sbjct: 1045 E----PPPCPEPGILSPSIVLTKAQEADRGEGPGKQVPAPRLRSFTCSSSAEGRAAGGDK 1100

Query: 1260 PESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQEPLVPVAAP 1309
             + + KT  +S+       P+KP  +   Q + P P  R   P +PV +P
Sbjct: 1101 SQGKPKTPVSSQAPVPAKRPIKPSRSEINQQTPPTPTPR---PPLPVKSP 1147



 Score = 42.4 bits (98), Expect = 0.004
 Identities = 52/219 (23%), Positives = 76/219 (34%), Gaps = 36/219 (16%)

Query: 1070 QPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPS-----LPIRPSRAPSRTPGPPSAQSSP 1124
            QP   S LG     SP T P Q P   +  +PS     LP R   +     G  +  + P
Sbjct: 945  QPPKDSPLGPCRGESPPTPPGQPPISPKKFLPSTANRGLPPRTQESRPSDLGKNAGDTLP 1004

Query: 1125 IDAQPAT------------------PLPQKDPAQPLEPKRPPPPRP---VAPP----TRP 1159
             +  P T                  P P+KD   P  P++ PPP P   +  P    T+ 
Sbjct: 1005 QEDLPLTKPEMFENPLYGSLSSFPKPAPRKDQESPKMPRKEPPPCPEPGILSPSIVLTKA 1064

Query: 1160 APPQRPPPPSGARSPAPTRKEFG-GIGAPPSPGVARREMEAPKSPGTTRKDNIGRSQPSP 1218
                R   P G + PAP  + F     A        +    PK+P +++     +    P
Sbjct: 1065 QEADRGEGP-GKQVPAPRLRSFTCSSSAEGRAAGGDKSQGKPKTPVSSQAPVPAKRPIKP 1123

Query: 1219 QAGLAGPGPAGYSTARPTIPPRAGVISAPQSHARASAGR 1257
                         T RP +P ++  +     H + S GR
Sbjct: 1124 SRSEINQQTPPTPTPRPPLPVKSPAV----LHLQHSKGR 1158


>gi|64085167 SH2 containing inositol phosphatase isoform a [Homo
            sapiens]
          Length = 1189

 Score =  177 bits (450), Expect = 6e-44
 Identities = 205/830 (24%), Positives = 331/830 (39%), Gaps = 141/830 (16%)

Query: 554  KVLKSMCENFYKYSKPKKIRVCVGTWNVNGGKQFRSIAFKNQTLTDWLLDAPKLAGIQEF 613
            ++L+ M     +  +P  I + +GTWN+      + I       T W L   K  G    
Sbjct: 386  QLLQQMKNKHSEQPEPDMITIFIGTWNMGNAPPPKKI-------TSWFLS--KGQGKTRD 436

Query: 614  QDKRSKPTDIFAIGFEEMVELNAGNIVSASTTNQKLWAVELQKTISRDNK--YVLLASEQ 671
                  P DI+ IG +E               ++K W   L+ ++       +  +A   
Sbjct: 437  DSADYIPHDIYVIGTQE------------DPLSEKEWLEILKHSLQEITSVTFKTVAIHT 484

Query: 672  LVGVCLFVFIRPQHAPFIRDVAVDTVKTGMGGATGNKGAVAIRMLFHTTSLCFVCSHFAA 731
            L  + + V  +P+H   I  +  D VKTG+    GNKGAV +  +F+ TSL FV SH  +
Sbjct: 485  LWNIRIVVLAKPEHENRISHICTDNVKTGIANTLGNKGAVGVSFMFNGTSLGFVNSHLTS 544

Query: 732  GQSQVKERNEDFIEIARKLSF---PMGRMLFSH--DYVFWCGDFNYRIDLPN---EEVKE 783
            G  +   RN++++ I R L+     +     +H   ++FW GD NYR+DLP    E + +
Sbjct: 545  GSEKKLRRNQNYMNILRFLALGDKKLSPFNITHRFTHLFWFGDLNYRVDLPTWEAETIIQ 604

Query: 784  LIRQQNWDSLIAGDQLINQKNAGQVFRGFLEGKVTFAPTYKYD-LFSDDY------DTSE 836
             I+QQ +  L++ DQL+ ++   +VF  F E ++TFAPTY+++ L  D Y       T  
Sbjct: 605  KIKQQQYADLLSHDQLLTERREQKVFLHFEEEEITFAPTYRFERLTRDKYAYTKQKATGM 664

Query: 837  KCRTPAWTDRVLWRRRKWPFDRSAEDLDLLNASFQDESKILYTWTPGTLLHYGRAELKTS 896
            K   P+W DRVLW  + +P       + ++  S+   S I+                 TS
Sbjct: 665  KYNLPSWCDRVLW--KSYPL------VHVVCQSYGSTSDIM-----------------TS 699

Query: 897  DHRPVVALIDIDIFEVEAEERQNIYKEVIAVQGPPDGTVLVSIKSSLPENNFFDDALIDE 956
            DH PV A  +  +      +        +  QG  +     +   +  +  F+ +     
Sbjct: 700  DHSPVFATFEAGVTSQFVSKNG---PGTVDSQGQIEFLRCYATLKTKSQTKFYLE-FHSS 755

Query: 957  LLQQFASFGEVILIRFVEDKMWVTFLEGSSALNVLSLNGKELLNRTITIALKSPDWIKNL 1016
             L+ F    E       E ++ V F E    L  +  + + LL++ I I++KS D  ++ 
Sbjct: 756  CLESFVKSQEGENEEGSEGELVVKFGETLPKLKPIISDPEYLLDQHILISIKSSDSDESY 815

Query: 1017 EE---EMSLEKISIALPSSTSSTLLGEDAEVAADFDMEGDVDDYSAEVEELLPQHL--QP 1071
             E    + LE     LP  T  T  G   E+   F  E  +     +  E L   +  + 
Sbjct: 816  GEGCIALRLEATETQLPIYTPLTHHG---ELTGHFQGEIKLQTSQGKTREKLYDFVKTER 872

Query: 1072 SSSSGLGTSPS-----------SSPRTSPCQSPTISE------------GPVPSLPIRPS 1108
              SSG  T  S            + R  PC   +I+E            GP   L ++ +
Sbjct: 873  DESSGPKTLKSLTSHDPMKQWEVTSRAPPCSGSSITEIINPNYMGVGPFGPPMPLHVKQT 932

Query: 1109 RAPSRTPGPPSAQSSPIDAQPATPLPQKDPAQPLEPKRPP-PPRPVAPPT--RPAPP--Q 1163
             +P + P   S    P D+ P  P   + P  P  P +PP  P+   P T  R  PP  Q
Sbjct: 933  LSPDQQPTAWSYDQPPKDS-PLGPCRGESP--PTPPGQPPISPKKFLPSTANRGLPPRTQ 989

Query: 1164 RPPPPSGARSPAPTRKE---------------FGGIGAPPSPGVARREMEAPKSPGTTRK 1208
               P    ++   T  +               +G + + P P   R++ E+PK P   RK
Sbjct: 990  ESRPSDLGKNAGDTLPQEDLPLTKPEMFENPLYGSLSSFPKP-APRKDQESPKMP---RK 1045

Query: 1209 DNIGRSQPSPQAGLAGP---------GPAGYSTARPTIPPRAGVISAPQSHARASAGRLT 1259
            +      P P+ G+  P            G    +    PR    +   S    +AG   
Sbjct: 1046 E----PPPCPEPGILSPSIVLTKAQEADRGEGPGKQVPAPRLRSFTCSSSAEGRAAGGDK 1101

Query: 1260 PESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQEPLVPVAAP 1309
             + + KT  +S+       P+KP  +   Q + P P  R   P +PV +P
Sbjct: 1102 SQGKPKTPVSSQAPVPAKRPIKPSRSEINQQTPPTPTPR---PPLPVKSP 1148



 Score = 42.4 bits (98), Expect = 0.004
 Identities = 52/219 (23%), Positives = 76/219 (34%), Gaps = 36/219 (16%)

Query: 1070 QPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPS-----LPIRPSRAPSRTPGPPSAQSSP 1124
            QP   S LG     SP T P Q P   +  +PS     LP R   +     G  +  + P
Sbjct: 946  QPPKDSPLGPCRGESPPTPPGQPPISPKKFLPSTANRGLPPRTQESRPSDLGKNAGDTLP 1005

Query: 1125 IDAQPAT------------------PLPQKDPAQPLEPKRPPPPRP---VAPP----TRP 1159
             +  P T                  P P+KD   P  P++ PPP P   +  P    T+ 
Sbjct: 1006 QEDLPLTKPEMFENPLYGSLSSFPKPAPRKDQESPKMPRKEPPPCPEPGILSPSIVLTKA 1065

Query: 1160 APPQRPPPPSGARSPAPTRKEFG-GIGAPPSPGVARREMEAPKSPGTTRKDNIGRSQPSP 1218
                R   P G + PAP  + F     A        +    PK+P +++     +    P
Sbjct: 1066 QEADRGEGP-GKQVPAPRLRSFTCSSSAEGRAAGGDKSQGKPKTPVSSQAPVPAKRPIKP 1124

Query: 1219 QAGLAGPGPAGYSTARPTIPPRAGVISAPQSHARASAGR 1257
                         T RP +P ++  +     H + S GR
Sbjct: 1125 SRSEINQQTPPTPTPRPPLPVKSPAV----LHLQHSKGR 1159


>gi|50726960 phosphatidylinositol (4,5) bisphosphate 5-phosphatase, A
            [Homo sapiens]
          Length = 638

 Score =  162 bits (409), Expect = 3e-39
 Identities = 175/646 (27%), Positives = 269/646 (41%), Gaps = 96/646 (14%)

Query: 569  PKKIRVCVGTWNVNGGKQFRSIAFKNQTLTDWLLDAPKLAGIQEFQDKRSKPTDIFAIGF 628
            P + R+ V TWNV         A     +T  L     L G  +     S   D+ AIG 
Sbjct: 52   PSEPRITVVTWNVG-------TAMPPDDVTSLL----HLGGGDD-----SDGADMIAIGL 95

Query: 629  EEMVELNAGNIVSASTTNQKLWAVELQKTISRDNKYVLLASEQLVGVCLFVFIRPQHAPF 688
            +E+  +    +  A  T+Q  W+      +   N +VL++S ++ GV L +F +  H PF
Sbjct: 96   QEVNSMLNKRLKDALFTDQ--WSELFMDALGPFN-FVLVSSVRMQGVILLLFAKYYHLPF 152

Query: 689  IRDVAVDTVKTGMGGATGNKGAVAIRMLFHTTSLCFVCSHFAAGQSQVKERNEDFIEIAR 748
            +RDV  D  +TG+GG  GNKG V++R+      LCF+  H  A   + ++R ++F  I  
Sbjct: 153  LRDVQTDCTRTGLGGYWGNKGGVSVRLAAFGHMLCFLNCHLPAHMDKAEQRKDNFQTILS 212

Query: 749  KLSF--PMGRMLFSHDYVFWCGDFNYRIDLPN-EEVKELIRQQNWDSLIAGDQLINQKNA 805
               F  P  + +  HD VFW GD N+RI+  +   VK  I       L   DQL   KN 
Sbjct: 213  LQQFQGPGAQGILDHDLVFWFGDLNFRIESYDLHFVKFAIDSDQLHQLWEKDQLNMAKNT 272

Query: 806  GQVFRGFLEGKVTFAPTYKYDLFSDDYDTSEKCRTPAWTDRVLWRRR-----KWPFDRSA 860
              + +GF EG + FAPT+K+D+ ++ YDTS K R PAWTDR+LW+ +       P  R +
Sbjct: 273  WPILKGFQEGPLNFAPTFKFDVGTNKYDTSAKKRKPAWTDRILWKVKAPGGGPSPSGRKS 332

Query: 861  EDLDLLNASFQDESKILYTWTPGTLLHYGRAELKTSDHRPVVA--LIDIDIFEVEAEERQ 918
              L +   S++                    E   SDH+PV A  L+     +     R 
Sbjct: 333  HRLQVTQHSYR-----------------SHMEYTVSDHKPVAAQFLLQFAFRDDMPLVRL 375

Query: 919  NIYKEVIAVQGPPDGTVLVSIKSSLPENNFFDDALIDELLQQFASFGEVILIRFVEDKMW 978
             +  E +    P    V   +++    +++    L     +    +   +  +  ED   
Sbjct: 376  EVADEWVR---PEQAVVRYRMETVFARSSWDWIGLYRVGFRHCKDYVAYVWAKH-EDVDG 431

Query: 979  VTFLEGSSALNVLSLNGKELL-----NRTITIALKSPDWIKNLEEEMSLEKISIALPSST 1033
             T+    S  ++   +G  +L     N +I I +  P                I+LPSS 
Sbjct: 432  NTYQVTFSEESLPKGHGDFILGYYSHNHSILIGITEP--------------FQISLPSSE 477

Query: 1034 SSTLLGEDAEVAADFDMEGDVDDYSAEVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSP 1093
                L   +  ++    EG+ DD + E+       L P S S    SP  S R    +SP
Sbjct: 478  ----LASSSTDSSGTSSEGE-DDSTLEL-------LAPKSRS---PSPGKSKR-HRSRSP 521

Query: 1094 TISEGPVPSLPIRPS----RAPSRTPGPPSAQSSPIDAQPAT-----PLPQKDPAQPLEP 1144
             ++    P L +RPS    R  SR+P P S + S +    ++        ++ P+    P
Sbjct: 522  GLAR--FPGLALRPSSRERRGASRSPSPQSRRLSRVAPDRSSNGSSRGSSEEGPSGLPGP 579

Query: 1145 KRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRKEFGGIGAPPSP 1190
               PP  P +    PA       P G  S  P R+        PSP
Sbjct: 580  WAFPPAVPRSLGLLPALRLETVDPGGGGSWGPDREALAPNSLSPSP 625


>gi|222136583 inositol polyphosphate phosphatase-like 1 [Homo sapiens]
          Length = 1258

 Score =  154 bits (388), Expect = 9e-37
 Identities = 208/832 (25%), Positives = 331/832 (39%), Gaps = 176/832 (21%)

Query: 549  QSASSKVLKSMCENFYKYSKPKKIRVCVGTWNVNGGKQFRSIAFKNQTLTDWLLDAPKLA 608
            + A  ++L+ M     K  +P  I V +GTWN+      +++       T W        
Sbjct: 401  REAFCQLLQLMKNKHSKQDEPDMISVFIGTWNMGSVPPPKNV-------TSWFTSK---- 449

Query: 609  GIQEFQDKRSK--PTDIFAIGFEEMVELNAGNIVSASTTNQKLWAVELQKTISR--DNKY 664
            G+ +  D+ +   P DI+  G +E            ++   + W   L+  +    D  Y
Sbjct: 450  GLGKTLDEVTVTIPHDIYVFGTQE------------NSVGDREWLDLLRGGLKELTDLDY 497

Query: 665  VLLASEQLVGVCLFVFIRPQHAPFIRDVAVDTVKTGMGGATGNKGAVAIRMLFHTTSLCF 724
              +A + L  + + V ++P+H   I  V+  +VKTG+    GNKGAV +  +F+ TS  F
Sbjct: 498  RPIAMQSLWNIKVAVLVKPEHENRISHVSTSSVKTGIANTLGNKGAVGVSFMFNGTSFGF 557

Query: 725  VCSHFAAGQSQVKERNEDFIEIARKLSFPMGRMLFSHD------YVFWCGDFNYRIDLPN 778
            V  H  +G  +   RN+++++I R LS    R L + D      ++FW GD NYR+D+  
Sbjct: 558  VNCHLTSGNEKTARRNQNYLDILRLLSLG-DRQLNAFDISLRFTHLFWFGDLNYRLDMDI 616

Query: 779  EEVKELIRQQNWDSLIAGDQLINQKNAGQVFRGFLEGKVTFAPTYKYDLFSDD------- 831
            +E+   I ++ ++ L+  DQL  ++   +VF  F E +++F PTY+Y+  S D       
Sbjct: 617  QEILNYISRKEFEPLLRVDQLNLEREKHKVFLRFSEEEISFPPTYRYERGSRDTYAWHKQ 676

Query: 832  YDTSEKCRTPAWTDRVLWRRRKWPFDRSAEDLDLLNASF--------QDESKILYTWTPG 883
              T  +   P+W DR+LW        +S  +  ++  S+         D S +  T+  G
Sbjct: 677  KPTGVRTNVPSWCDRILW--------KSYPETHIICNSYGCTDDIVTSDHSPVFGTFEVG 728

Query: 884  TLLHY--GRAELKTSDHRPVVALIDIDIFE--VEAEERQNIYKEVIAVQGPPDGTVLVSI 939
                +   +   KTSD     A I+ +  E  V+   R   + E  +       T L   
Sbjct: 729  VTSQFISKKGLSKTSDQ----AYIEFESIEAIVKTASRTKFFIEFYS-------TCLEEY 777

Query: 940  KSSLPENNFFDDALIDELLQQFASFGEVILIRFVEDKMWVTFLEGSS-ALNVLSLNGKEL 998
            K S  EN+      I+ L  Q++S     L   + D   + +L+     L V S++G E 
Sbjct: 778  KKSF-ENDAQSSDNINFLKVQWSSRQLPTLKPILAD---IEYLQDQHLLLTVKSMDGYES 833

Query: 999  LNRTITIALKSP---------DWIKNLEEEMS--LEKISIALPSSTSSTLLGEDAEVAAD 1047
                + +ALKS           ++ +  EE       + + +P+    T           
Sbjct: 834  YGECV-VALKSMIGSTAQQFLTFLSHRGEETGNIRGSMKVRVPTERLGT----------- 881

Query: 1048 FDMEGDVDDYSAEVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEG--PVPSLPI 1105
               E   +  S + +E   +   PS S G     S  PR S  + P  +E   P+  L  
Sbjct: 882  --RERLYEWISIDKDEAGAKSKAPSVSRG-----SQEPR-SGSRKPAFTEASCPLSRLFE 933

Query: 1106 RPSRAP--SRTPGPPSAQSSPIDAQPATPLPQKDPAQP-LEPKRPPPPRPVAPPTRPAPP 1162
             P + P   R P PP A             P+++P  P L+P+  P P  VA        
Sbjct: 934  EPEKPPPTGRPPAPPRA------------APREEPLTPRLKPEGAPEPEGVA-------- 973

Query: 1163 QRPPPPSGARSPAPTRKEFGGIG---APPSPGVARREMEAPKSPGTTRKDNIGRSQPSPQ 1219
              PPP +   +PA    E  G+     PP P    R   AP    T  K+ +  + P+PQ
Sbjct: 974  -APPPKNSFNNPAYYVLE--GVPHQLLPPEPPSPAR---APVPSAT--KNKVAITVPAPQ 1025

Query: 1220 AGLAGPGPAGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEP 1279
             G                            H R   G     S  ++  T     F P P
Sbjct: 1026 LG-------------------------HHRHPRVGEG---SSSDEESGGTLPPPDFPPPP 1057

Query: 1280 LKPQAAFPPQS--SLPPPAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRS 1329
            L   A F P S   LP P  R +        P P++ P+P L  PP P P S
Sbjct: 1058 LPDSAIFLPPSLDPLPGPVVRGRGGAEARGPPPPKAHPRPPL--PPGPSPAS 1107


>gi|38327539 inositol polyphosphate-5-phosphatase E [Homo sapiens]
          Length = 644

 Score =  135 bits (341), Expect = 2e-31
 Identities = 104/360 (28%), Positives = 159/360 (44%), Gaps = 71/360 (19%)

Query: 565 KYSKPKKIRVCVGTWNVNGGKQFRSIAFKNQTLTDWLLDAPKLAGIQEFQDKRSKPTDIF 624
           +Y   + + + V TWN+ G K+         +L ++LL A           +     D++
Sbjct: 292 RYFPDRNVALFVATWNMQGQKELPP------SLDEFLLPA-----------EADYAQDLY 334

Query: 625 AIGFEEMVELNAGNIVSASTTNQKLWAVELQKTISRDNKYVLLASEQLVGVCLFVFIRPQ 684
            IG +E              ++++ W   LQ+T+     YVLL+S     + + +FIR  
Sbjct: 335 VIGVQE------------GCSDRREWETRLQETLGPH--YVLLSSAAHGVLYMSLFIRRD 380

Query: 685 HAPFIRDVAVDTVKTGMGGATGNKGAVAIRMLFHTTSLCFVCSHFAAGQSQVKERNEDFI 744
              F  +V   TV T +      KGA+ I   F  TS  F+ SHF +G  +V ER  D+ 
Sbjct: 381 LIWFCSEVECSTVTTRIVSQIKTKGALGISFTFFGTSFLFITSHFTSGDGKVAERLLDYT 440

Query: 745 EIARKLSFPMG------------RMLFSHDYVFWCGDFNYRIDLPNEEVKELIRQQ---N 789
              + L  P               +    D VFW GDFN+R+      V  L+ Q    +
Sbjct: 441 RTVQALVLPRNVPDTNPYRSSAADVTTRFDEVFWFGDFNFRLSGGRTVVDALLCQGLVVD 500

Query: 790 WDSLIAGDQLINQKNAGQVFRGFLEGKVTFAPTYKYDLFSDDYDTSEKCRTPAWTDRVLW 849
             +L+  DQLI +   G +F+GF E  + F P+YK+D+  D YD++ K RTP++TDRVL+
Sbjct: 501 VPALLQHDQLIREMRKGSIFKGFQEPDIHFLPSYKFDIGKDTYDSTSKQRTPSYTDRVLY 560

Query: 850 RRRKWPFDRSAEDLDLLNASFQDESKILYTWTPGTLLHYGRAELKTSDHRPVVALIDIDI 909
           R R                   D   + Y+  PG         +KTSDHRPV  L  + +
Sbjct: 561 RSR----------------HKGDICPVSYSSCPG---------IKTSDHRPVYGLFRVKV 595



 Score = 39.3 bits (90), Expect = 0.031
 Identities = 48/200 (24%), Positives = 71/200 (35%), Gaps = 37/200 (18%)

Query: 1128 QPATPLPQKDPAQPLE---PKRPPPPRPVAPPTRPAPP------QRPPPPSGARSPA--- 1175
            +P+ P PQ    + L+   P  PP  R  +PP  P           P  PSG   PA   
Sbjct: 9    RPSEPAPQPPEGRTLQGQLPGAPPAQRAGSPPDAPGSESPALACSTPATPSGEDPPARAA 68

Query: 1176 ------PTRKEFGGIGAPPSPGVARREMEAPKSPGTTRKDNIGRSQPSPQAGLA---GPG 1226
                  P R       +    G  RR          +++D   R+  SP  G     GPG
Sbjct: 69   PIAPRPPARPRLERALSLDDKGWRRRRFRG------SQEDLEARNGTSPSRGSVQSEGPG 122

Query: 1227 -------PAGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEP 1279
                   P   ST+   IP   GV+S+ +    +    L+  + S  +   + +      
Sbjct: 123  APAHSCSPPCLSTSLQEIPKSRGVLSSERGSPSSGGNPLSGVASSSPNLPHRDAAVAGSS 182

Query: 1280 LKPQAAFPPQSSLPPPAQRL 1299
             +  +  PP+   PPPA  L
Sbjct: 183  PRLPSLLPPR---PPPALSL 199


>gi|18765709 inositol polyphosphate-5-phosphatase K isoform 1 [Homo
           sapiens]
          Length = 448

 Score =  133 bits (335), Expect = 1e-30
 Identities = 98/301 (32%), Positives = 153/301 (50%), Gaps = 23/301 (7%)

Query: 615 DKRSKPTDIFAIGFEEMVELNAG--NIVSASTTNQKLWAVELQKTISRDNKYVLLASEQL 672
           + R+   DI+ IG +E   LN+G  +++S +  N   W+  L   +S    ++ ++  ++
Sbjct: 39  NNRNLNLDIYVIGLQE---LNSGIISLLSDAAFNDS-WSSFLMDVLS-PLSFIKVSHVRM 93

Query: 673 VGVCLFVFIRPQHAPFIRDVAVDTVKTGMGGATGNKGAVAIRMLFHTTSLCFVCSHFAAG 732
            G+ L VF + QH P+I+ ++  +  TG+ G  GNKG V I +  +   +  +  H    
Sbjct: 94  QGILLLVFAKYQHLPYIQILSTKSTPTGLFGYWGNKGGVNICLKLYGYYVSIINCHLPPH 153

Query: 733 QSQVKERNEDFIEIARKLSFPMGR---MLFSHDYVFWCGDFNYRI-DLPNEEVKELIRQQ 788
            S   +R E F  I    +   GR    +  HD + W GD N+RI D     V+E I+ +
Sbjct: 154 ISNNYQRLEHFDRILEMQNCE-GRDIPNILDHDLIIWFGDMNFRIEDFGLHFVRESIKNR 212

Query: 789 NWDSLIAGDQLINQKNAGQVFRGFLEGKVTFAPTYKYDLFSDDYDTSEKCRTPAWTDRVL 848
            +  L   DQL   K    + R F EG++ F PTYK+D  S+DYDTSEK R PAWTDR+L
Sbjct: 213 CYGGLWEKDQLSIAKKHDPLLREFQEGRLLFPPTYKFDRNSNDYDTSEKKRKPAWTDRIL 272

Query: 849 WRRRKWPFDRSAEDLDLLNASFQDESKILYTWTPGTLLHYGRAELKTSDHRPVVALIDID 908
           WR ++ P   +  D  +  AS    S   Y+    + + YG      SDH+PV    D++
Sbjct: 273 WRLKRQPC--AGPDTPIPPASHFSLSLRGYS----SHMTYG-----ISDHKPVSGTFDLE 321

Query: 909 I 909
           +
Sbjct: 322 L 322


>gi|208610044 inositol polyphosphate-5-phosphatase K isoform 2 [Homo
           sapiens]
          Length = 372

 Score =  125 bits (314), Expect = 3e-28
 Identities = 84/250 (33%), Positives = 128/250 (51%), Gaps = 16/250 (6%)

Query: 664 YVLLASEQLVGVCLFVFIRPQHAPFIRDVAVDTVKTGMGGATGNKGAVAIRMLFHTTSLC 723
           ++ ++  ++ G+ L VF + QH P+I+ ++  +  TG+ G  GNKG V I +  +   + 
Sbjct: 9   FIKVSHVRMQGILLLVFAKYQHLPYIQILSTKSTPTGLFGYWGNKGGVNICLKLYGYYVS 68

Query: 724 FVCSHFAAGQSQVKERNEDFIEIARKLSFPMGR---MLFSHDYVFWCGDFNYRI-DLPNE 779
            +  H     S   +R E F  I    +   GR    +  HD + W GD N+RI D    
Sbjct: 69  IINCHLPPHISNNYQRLEHFDRILEMQNCE-GRDIPNILDHDLIIWFGDMNFRIEDFGLH 127

Query: 780 EVKELIRQQNWDSLIAGDQLINQKNAGQVFRGFLEGKVTFAPTYKYDLFSDDYDTSEKCR 839
            V+E I+ + +  L   DQL   K    + R F EG++ F PTYK+D  S+DYDTSEK R
Sbjct: 128 FVRESIKNRCYGGLWEKDQLSIAKKHDPLLREFQEGRLLFPPTYKFDRNSNDYDTSEKKR 187

Query: 840 TPAWTDRVLWRRRKWPFDRSAEDLDLLNASFQDESKILYTWTPGTLLHYGRAELKTSDHR 899
            PAWTDR+LWR ++ P   +  D  +  AS    S   Y+    + + YG      SDH+
Sbjct: 188 KPAWTDRILWRLKRQPC--AGPDTPIPPASHFSLSLRGYS----SHMTYG-----ISDHK 236

Query: 900 PVVALIDIDI 909
           PV    D+++
Sbjct: 237 PVSGTFDLEL 246


>gi|18765707 inositol polyphosphate-5-phosphatase K isoform 2 [Homo
           sapiens]
          Length = 372

 Score =  125 bits (314), Expect = 3e-28
 Identities = 84/250 (33%), Positives = 128/250 (51%), Gaps = 16/250 (6%)

Query: 664 YVLLASEQLVGVCLFVFIRPQHAPFIRDVAVDTVKTGMGGATGNKGAVAIRMLFHTTSLC 723
           ++ ++  ++ G+ L VF + QH P+I+ ++  +  TG+ G  GNKG V I +  +   + 
Sbjct: 9   FIKVSHVRMQGILLLVFAKYQHLPYIQILSTKSTPTGLFGYWGNKGGVNICLKLYGYYVS 68

Query: 724 FVCSHFAAGQSQVKERNEDFIEIARKLSFPMGR---MLFSHDYVFWCGDFNYRI-DLPNE 779
            +  H     S   +R E F  I    +   GR    +  HD + W GD N+RI D    
Sbjct: 69  IINCHLPPHISNNYQRLEHFDRILEMQNCE-GRDIPNILDHDLIIWFGDMNFRIEDFGLH 127

Query: 780 EVKELIRQQNWDSLIAGDQLINQKNAGQVFRGFLEGKVTFAPTYKYDLFSDDYDTSEKCR 839
            V+E I+ + +  L   DQL   K    + R F EG++ F PTYK+D  S+DYDTSEK R
Sbjct: 128 FVRESIKNRCYGGLWEKDQLSIAKKHDPLLREFQEGRLLFPPTYKFDRNSNDYDTSEKKR 187

Query: 840 TPAWTDRVLWRRRKWPFDRSAEDLDLLNASFQDESKILYTWTPGTLLHYGRAELKTSDHR 899
            PAWTDR+LWR ++ P   +  D  +  AS    S   Y+    + + YG      SDH+
Sbjct: 188 KPAWTDRILWRLKRQPC--AGPDTPIPPASHFSLSLRGYS----SHMTYG-----ISDHK 236

Query: 900 PVVALIDIDI 909
           PV    D+++
Sbjct: 237 PVSGTFDLEL 246


>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
          Length = 1270

 Score = 96.7 bits (239), Expect = 2e-19
 Identities = 123/533 (23%), Positives = 187/533 (35%), Gaps = 60/533 (11%)

Query: 1079 TSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQPATPLPQKDP 1138
            T+  S+P T    +PT ++ P P+ P  P+   ++ P P + +S+P   +   P   K P
Sbjct: 250  TTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKP 309

Query: 1139 AQPLEPKRPPPPRPVAP----PTRPAPPQRPPPPSGARSPAPTRKEFGGIGAPPSPGVAR 1194
            A P  PK P P  P  P    P  PAP  + P P+  + PAPT        AP  P    
Sbjct: 310  A-PTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPT--------APKKPAPTT 360

Query: 1195 REMEAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAGYSTARPTIPPRAGVISAPQSHARAS 1254
             +  AP +P           +P+P      P P       PT    A   +   +     
Sbjct: 361  PKEPAPTTP----------KEPAPTT-TKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTK 409

Query: 1255 AGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQEPLVPVAAPMPQSG 1314
            +   TP+  S T      +T  P P  P+   P     P P    +        P P + 
Sbjct: 410  SAPTTPKEPSPT------TTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTT 463

Query: 1315 PQPNLETPPQPPPRSRSSHSLPSEASSQPQVKTNGISDGKRESPLKIDPFEDLSFNLLAV 1374
             +P   TP +P P +    + P+            ++    E P    P E      LA 
Sbjct: 464  KKPAPTTPKEPAP-TTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEE------LAP 516

Query: 1375 SKAQLSVQTSPVPTPDPKRLIQLPSATQSNVLSSVSCMPTMPPIPARSQSQENMRSSPNP 1434
            +  +      P PT   +     P A   N     +  PT P  PA +  +E   ++P  
Sbjct: 517  TTPE-----EPTPTTPEEPAPTTPKAAAPNTPKEPA--PTTPKEPAPTTPKEPAPTTPKE 569

Query: 1435 FI-TGLTRTNPFSDRTAAPGNPFRAKSEESEATSWFSKEEPVTISPFPSLQPLGHNKSRA 1493
               T    T P + +  AP  P +   +E   T+           P P+       K  A
Sbjct: 570  TAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTP-----KGTA 624

Query: 1494 SSSLDGFKDSFDLQGQSTLKISNPKGWVTFEEEEDFGVKGKSKSACSDLLGNQPSSFSGS 1553
             ++      +   +   T     PKG      +E      K K A  +L    P++  G 
Sbjct: 625  PTTPKEPAPTTPKEPAPT----TPKGTAPTTLKEPAPTTPK-KPAPKEL---APTTTKGP 676

Query: 1554 NLTLNDDWNKGTNVSFCVLPSRRPPPPPVPLLPPGTSPPVDPFTTLASKASPT 1606
              T +D     T        + + P P  P  P  T+P   P TT +  ++PT
Sbjct: 677  TSTTSDK-PAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTT-SEVSTPT 727



 Score = 70.5 bits (171), Expect = 1e-11
 Identities = 120/568 (21%), Positives = 195/568 (34%), Gaps = 59/568 (10%)

Query: 1065 LPQHLQPSSSSGLGTSPSSS---PRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQ 1121
            LP +   S  + L  +  ++     T+     T ++G   +   + +++  +T     A 
Sbjct: 130  LPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAP 189

Query: 1122 SSPIDAQPATPLPQKDPAQP--LEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRK 1179
            +S + A+P TP  +     P    PK P P  P  P    +   + P P+  +S   T K
Sbjct: 190  TSKVLAKP-TPKAETTTKGPALTTPKEPTPTTPKEP---ASTTPKEPTPTTIKSAPTTPK 245

Query: 1180 EFGGIGAPPSPGVARREMEAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAGYST-ARPTIP 1238
            E       P+P   +     PK P  T       + P   A      PA  +T + PT P
Sbjct: 246  E-------PAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTP 298

Query: 1239 -------PRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSS 1291
                   P+    + P+  A  +    TP +  + + T+K     P P  P+   P    
Sbjct: 299  KEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKE----PAPTTPKEPAPTAPK 354

Query: 1292 LPPPAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSS------HSLPSEASSQPQV 1345
             P P    +        P P +  +P+  TP +P P +  S         P+   S P  
Sbjct: 355  KPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTT 414

Query: 1346 KTNGISDGKRESPLKIDPFEDLSFNLLAVSKAQLSVQTSPVPTPDPKRLIQLPSATQSNV 1405
                 S    + P    P E          K   +    P PT  PK     P+ T+   
Sbjct: 415  PKEP-SPTTTKEPAPTTPKEPAP---TTPKKPAPTTPKEPAPT-TPKE--PAPTTTKKPA 467

Query: 1406 LSSVSCMPTMPPIPARSQSQENMRSSPNPFI-TGLTRTNPFSDRTAAPGNPFRAKSEESE 1464
                   PT P  PA +  +E   ++P     T   +  P +    AP  P        E
Sbjct: 468  -------PTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPE 520

Query: 1465 ATSWFSKEEPVTISPFPSLQPLGHNKSRASSSLDGFKDSFDLQGQSTLK---ISNPKGW- 1520
              +  + EEP   +P  +  P    +   ++  +    +      +T K    + PKG  
Sbjct: 521  EPTPTTPEEPAPTTP-KAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTA 579

Query: 1521 -VTFEEEEDFGVKGKSKSACSDLLGNQPSSFSGSNLTLNDDWNKGTNVSFCVLPSRRPPP 1579
              T +E      K  +    +     +P+S +           KGT  +    P+   P 
Sbjct: 580  PTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTP--KGTAPTTPKEPAPTTPK 637

Query: 1580 PPVPLLPPGTSPPV--DPFTTLASKASP 1605
             P P  P GT+P    +P  T   K +P
Sbjct: 638  EPAPTTPKGTAPTTLKEPAPTTPKKPAP 665



 Score = 63.9 bits (154), Expect = 1e-09
 Identities = 73/330 (22%), Positives = 114/330 (34%), Gaps = 55/330 (16%)

Query: 1066 PQHLQPSS-SSGLGTSPSS-SPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSA-QS 1122
            P+ L P++      T+P   +P T    +P   + P P+ P  P+    + P P +  ++
Sbjct: 511  PEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKET 570

Query: 1123 SPIDAQPATPLPQKDPAQPLEPKRPPP------------------PRPVAPP-TRPAPPQ 1163
            +P   +   P   K+PA P  PK+P P                  P P  P  T P  P+
Sbjct: 571  APTTPKGTAPTTLKEPA-PTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPK 629

Query: 1164 RPPP-------PSGARSPAPTRKEFGGIGAPPSPGVARREMEAPKSPGTTRKDNIGRSQP 1216
             P P       P+  +  APT  +      P  P          K P +T  D    + P
Sbjct: 630  EPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTP 689

Query: 1217 SPQAGLAGPGPAGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFL 1276
               A      PA      PT P +     AP           TPE+   T+      T  
Sbjct: 690  KETAPTTPKEPA------PTTPKK----PAP----------TTPETPPPTTSEVSTPTTT 729

Query: 1277 PEPL----KPQAAFPPQSSLPPPAQRLQEPLVP-VAAPMPQSGPQPNLETPPQPPPRSRS 1331
             EP      P  + P  S+ P P      P  P V      +  +P + T  +     R 
Sbjct: 730  KEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERD 789

Query: 1332 SHSLPSEASSQPQVKTNGISDGKRESPLKI 1361
              + P   ++ P++     +  ++ +  KI
Sbjct: 790  LRTTPETTTAAPKMTKETATTTEKTTESKI 819



 Score = 33.1 bits (74), Expect = 2.2
 Identities = 49/247 (19%), Positives = 86/247 (34%), Gaps = 21/247 (8%)

Query: 1008 KSPDWIKNLEEEMSLEKISIALPSS----------TSSTLLGEDAEVAADFDMEGDVDDY 1057
            KSPD       E+S E    AL +S          T +    E    A D   E D+   
Sbjct: 737  KSPD---ESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRT- 792

Query: 1058 SAEVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVP---SLPIRPSRAPSRT 1114
            + E     P+  + ++++   T+ S    T+   + T ++   P   +     + AP  T
Sbjct: 793  TPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVT 852

Query: 1115 PGPPSAQSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSP 1174
                +  ++ I  +P      KD A   +   P P +P   P +P   ++P      R P
Sbjct: 853  TTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKP 912

Query: 1175 --APTRKEFGGI--GAPPSPGVARREMEAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAGY 1230
               PT ++         P+  +A   ++    P  T    +    P  +      G   +
Sbjct: 913  KTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSEDAGGAEGETPH 972

Query: 1231 STARPTI 1237
               RP +
Sbjct: 973  MLLRPHV 979


>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
          Length = 1311

 Score = 96.7 bits (239), Expect = 2e-19
 Identities = 123/533 (23%), Positives = 187/533 (35%), Gaps = 60/533 (11%)

Query: 1079 TSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQPATPLPQKDP 1138
            T+  S+P T    +PT ++ P P+ P  P+   ++ P P + +S+P   +   P   K P
Sbjct: 291  TTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKP 350

Query: 1139 AQPLEPKRPPPPRPVAP----PTRPAPPQRPPPPSGARSPAPTRKEFGGIGAPPSPGVAR 1194
            A P  PK P P  P  P    P  PAP  + P P+  + PAPT        AP  P    
Sbjct: 351  A-PTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPT--------APKKPAPTT 401

Query: 1195 REMEAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAGYSTARPTIPPRAGVISAPQSHARAS 1254
             +  AP +P           +P+P      P P       PT    A   +   +     
Sbjct: 402  PKEPAPTTP----------KEPAPTT-TKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTK 450

Query: 1255 AGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQEPLVPVAAPMPQSG 1314
            +   TP+  S T      +T  P P  P+   P     P P    +        P P + 
Sbjct: 451  SAPTTPKEPSPT------TTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTT 504

Query: 1315 PQPNLETPPQPPPRSRSSHSLPSEASSQPQVKTNGISDGKRESPLKIDPFEDLSFNLLAV 1374
             +P   TP +P P +    + P+            ++    E P    P E      LA 
Sbjct: 505  KKPAPTTPKEPAP-TTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEE------LAP 557

Query: 1375 SKAQLSVQTSPVPTPDPKRLIQLPSATQSNVLSSVSCMPTMPPIPARSQSQENMRSSPNP 1434
            +  +      P PT   +     P A   N     +  PT P  PA +  +E   ++P  
Sbjct: 558  TTPE-----EPTPTTPEEPAPTTPKAAAPNTPKEPA--PTTPKEPAPTTPKEPAPTTPKE 610

Query: 1435 FI-TGLTRTNPFSDRTAAPGNPFRAKSEESEATSWFSKEEPVTISPFPSLQPLGHNKSRA 1493
               T    T P + +  AP  P +   +E   T+           P P+       K  A
Sbjct: 611  TAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTP-----KGTA 665

Query: 1494 SSSLDGFKDSFDLQGQSTLKISNPKGWVTFEEEEDFGVKGKSKSACSDLLGNQPSSFSGS 1553
             ++      +   +   T     PKG      +E      K K A  +L    P++  G 
Sbjct: 666  PTTPKEPAPTTPKEPAPT----TPKGTAPTTLKEPAPTTPK-KPAPKEL---APTTTKGP 717

Query: 1554 NLTLNDDWNKGTNVSFCVLPSRRPPPPPVPLLPPGTSPPVDPFTTLASKASPT 1606
              T +D     T        + + P P  P  P  T+P   P TT +  ++PT
Sbjct: 718  TSTTSDK-PAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTT-SEVSTPT 768



 Score = 70.5 bits (171), Expect = 1e-11
 Identities = 120/568 (21%), Positives = 195/568 (34%), Gaps = 59/568 (10%)

Query: 1065 LPQHLQPSSSSGLGTSPSSS---PRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQ 1121
            LP +   S  + L  +  ++     T+     T ++G   +   + +++  +T     A 
Sbjct: 171  LPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAP 230

Query: 1122 SSPIDAQPATPLPQKDPAQP--LEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRK 1179
            +S + A+P TP  +     P    PK P P  P  P    +   + P P+  +S   T K
Sbjct: 231  TSKVLAKP-TPKAETTTKGPALTTPKEPTPTTPKEP---ASTTPKEPTPTTIKSAPTTPK 286

Query: 1180 EFGGIGAPPSPGVARREMEAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAGYST-ARPTIP 1238
            E       P+P   +     PK P  T       + P   A      PA  +T + PT P
Sbjct: 287  E-------PAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTP 339

Query: 1239 -------PRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSS 1291
                   P+    + P+  A  +    TP +  + + T+K     P P  P+   P    
Sbjct: 340  KEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKE----PAPTTPKEPAPTAPK 395

Query: 1292 LPPPAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSS------HSLPSEASSQPQV 1345
             P P    +        P P +  +P+  TP +P P +  S         P+   S P  
Sbjct: 396  KPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTT 455

Query: 1346 KTNGISDGKRESPLKIDPFEDLSFNLLAVSKAQLSVQTSPVPTPDPKRLIQLPSATQSNV 1405
                 S    + P    P E          K   +    P PT  PK     P+ T+   
Sbjct: 456  PKEP-SPTTTKEPAPTTPKEPAP---TTPKKPAPTTPKEPAPT-TPKE--PAPTTTKKPA 508

Query: 1406 LSSVSCMPTMPPIPARSQSQENMRSSPNPFI-TGLTRTNPFSDRTAAPGNPFRAKSEESE 1464
                   PT P  PA +  +E   ++P     T   +  P +    AP  P        E
Sbjct: 509  -------PTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPE 561

Query: 1465 ATSWFSKEEPVTISPFPSLQPLGHNKSRASSSLDGFKDSFDLQGQSTLK---ISNPKGW- 1520
              +  + EEP   +P  +  P    +   ++  +    +      +T K    + PKG  
Sbjct: 562  EPTPTTPEEPAPTTP-KAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTA 620

Query: 1521 -VTFEEEEDFGVKGKSKSACSDLLGNQPSSFSGSNLTLNDDWNKGTNVSFCVLPSRRPPP 1579
              T +E      K  +    +     +P+S +           KGT  +    P+   P 
Sbjct: 621  PTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTP--KGTAPTTPKEPAPTTPK 678

Query: 1580 PPVPLLPPGTSPPV--DPFTTLASKASP 1605
             P P  P GT+P    +P  T   K +P
Sbjct: 679  EPAPTTPKGTAPTTLKEPAPTTPKKPAP 706



 Score = 63.9 bits (154), Expect = 1e-09
 Identities = 73/330 (22%), Positives = 114/330 (34%), Gaps = 55/330 (16%)

Query: 1066 PQHLQPSS-SSGLGTSPSS-SPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSA-QS 1122
            P+ L P++      T+P   +P T    +P   + P P+ P  P+    + P P +  ++
Sbjct: 552  PEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKET 611

Query: 1123 SPIDAQPATPLPQKDPAQPLEPKRPPP------------------PRPVAPP-TRPAPPQ 1163
            +P   +   P   K+PA P  PK+P P                  P P  P  T P  P+
Sbjct: 612  APTTPKGTAPTTLKEPA-PTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPK 670

Query: 1164 RPPP-------PSGARSPAPTRKEFGGIGAPPSPGVARREMEAPKSPGTTRKDNIGRSQP 1216
             P P       P+  +  APT  +      P  P          K P +T  D    + P
Sbjct: 671  EPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTP 730

Query: 1217 SPQAGLAGPGPAGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFL 1276
               A      PA      PT P +     AP           TPE+   T+      T  
Sbjct: 731  KETAPTTPKEPA------PTTPKK----PAP----------TTPETPPPTTSEVSTPTTT 770

Query: 1277 PEPL----KPQAAFPPQSSLPPPAQRLQEPLVP-VAAPMPQSGPQPNLETPPQPPPRSRS 1331
             EP      P  + P  S+ P P      P  P V      +  +P + T  +     R 
Sbjct: 771  KEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERD 830

Query: 1332 SHSLPSEASSQPQVKTNGISDGKRESPLKI 1361
              + P   ++ P++     +  ++ +  KI
Sbjct: 831  LRTTPETTTAAPKMTKETATTTEKTTESKI 860



 Score = 33.1 bits (74), Expect = 2.2
 Identities = 49/247 (19%), Positives = 86/247 (34%), Gaps = 21/247 (8%)

Query: 1008 KSPDWIKNLEEEMSLEKISIALPSS----------TSSTLLGEDAEVAADFDMEGDVDDY 1057
            KSPD       E+S E    AL +S          T +    E    A D   E D+   
Sbjct: 778  KSPD---ESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRT- 833

Query: 1058 SAEVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVP---SLPIRPSRAPSRT 1114
            + E     P+  + ++++   T+ S    T+   + T ++   P   +     + AP  T
Sbjct: 834  TPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVT 893

Query: 1115 PGPPSAQSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSP 1174
                +  ++ I  +P      KD A   +   P P +P   P +P   ++P      R P
Sbjct: 894  TTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKP 953

Query: 1175 --APTRKEFGGI--GAPPSPGVARREMEAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAGY 1230
               PT ++         P+  +A   ++    P  T    +    P  +      G   +
Sbjct: 954  KTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSEDAGGAEGETPH 1013

Query: 1231 STARPTI 1237
               RP +
Sbjct: 1014 MLLRPHV 1020


>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
          Length = 1363

 Score = 96.7 bits (239), Expect = 2e-19
 Identities = 123/533 (23%), Positives = 187/533 (35%), Gaps = 60/533 (11%)

Query: 1079 TSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQPATPLPQKDP 1138
            T+  S+P T    +PT ++ P P+ P  P+   ++ P P + +S+P   +   P   K P
Sbjct: 343  TTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKP 402

Query: 1139 AQPLEPKRPPPPRPVAP----PTRPAPPQRPPPPSGARSPAPTRKEFGGIGAPPSPGVAR 1194
            A P  PK P P  P  P    P  PAP  + P P+  + PAPT        AP  P    
Sbjct: 403  A-PTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPT--------APKKPAPTT 453

Query: 1195 REMEAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAGYSTARPTIPPRAGVISAPQSHARAS 1254
             +  AP +P           +P+P      P P       PT    A   +   +     
Sbjct: 454  PKEPAPTTP----------KEPAPTT-TKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTK 502

Query: 1255 AGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQEPLVPVAAPMPQSG 1314
            +   TP+  S T      +T  P P  P+   P     P P    +        P P + 
Sbjct: 503  SAPTTPKEPSPT------TTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTT 556

Query: 1315 PQPNLETPPQPPPRSRSSHSLPSEASSQPQVKTNGISDGKRESPLKIDPFEDLSFNLLAV 1374
             +P   TP +P P +    + P+            ++    E P    P E      LA 
Sbjct: 557  KKPAPTTPKEPAP-TTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEE------LAP 609

Query: 1375 SKAQLSVQTSPVPTPDPKRLIQLPSATQSNVLSSVSCMPTMPPIPARSQSQENMRSSPNP 1434
            +  +      P PT   +     P A   N     +  PT P  PA +  +E   ++P  
Sbjct: 610  TTPE-----EPTPTTPEEPAPTTPKAAAPNTPKEPA--PTTPKEPAPTTPKEPAPTTPKE 662

Query: 1435 FI-TGLTRTNPFSDRTAAPGNPFRAKSEESEATSWFSKEEPVTISPFPSLQPLGHNKSRA 1493
               T    T P + +  AP  P +   +E   T+           P P+       K  A
Sbjct: 663  TAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTP-----KGTA 717

Query: 1494 SSSLDGFKDSFDLQGQSTLKISNPKGWVTFEEEEDFGVKGKSKSACSDLLGNQPSSFSGS 1553
             ++      +   +   T     PKG      +E      K K A  +L    P++  G 
Sbjct: 718  PTTPKEPAPTTPKEPAPT----TPKGTAPTTLKEPAPTTPK-KPAPKEL---APTTTKGP 769

Query: 1554 NLTLNDDWNKGTNVSFCVLPSRRPPPPPVPLLPPGTSPPVDPFTTLASKASPT 1606
              T +D     T        + + P P  P  P  T+P   P TT +  ++PT
Sbjct: 770  TSTTSDK-PAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTT-SEVSTPT 820



 Score = 70.5 bits (171), Expect = 1e-11
 Identities = 120/568 (21%), Positives = 195/568 (34%), Gaps = 59/568 (10%)

Query: 1065 LPQHLQPSSSSGLGTSPSSS---PRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQ 1121
            LP +   S  + L  +  ++     T+     T ++G   +   + +++  +T     A 
Sbjct: 223  LPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAP 282

Query: 1122 SSPIDAQPATPLPQKDPAQP--LEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRK 1179
            +S + A+P TP  +     P    PK P P  P  P    +   + P P+  +S   T K
Sbjct: 283  TSKVLAKP-TPKAETTTKGPALTTPKEPTPTTPKEP---ASTTPKEPTPTTIKSAPTTPK 338

Query: 1180 EFGGIGAPPSPGVARREMEAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAGYST-ARPTIP 1238
            E       P+P   +     PK P  T       + P   A      PA  +T + PT P
Sbjct: 339  E-------PAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTP 391

Query: 1239 -------PRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSS 1291
                   P+    + P+  A  +    TP +  + + T+K     P P  P+   P    
Sbjct: 392  KEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKE----PAPTTPKEPAPTAPK 447

Query: 1292 LPPPAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSS------HSLPSEASSQPQV 1345
             P P    +        P P +  +P+  TP +P P +  S         P+   S P  
Sbjct: 448  KPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTT 507

Query: 1346 KTNGISDGKRESPLKIDPFEDLSFNLLAVSKAQLSVQTSPVPTPDPKRLIQLPSATQSNV 1405
                 S    + P    P E          K   +    P PT  PK     P+ T+   
Sbjct: 508  PKEP-SPTTTKEPAPTTPKEPAP---TTPKKPAPTTPKEPAPT-TPKE--PAPTTTKKPA 560

Query: 1406 LSSVSCMPTMPPIPARSQSQENMRSSPNPFI-TGLTRTNPFSDRTAAPGNPFRAKSEESE 1464
                   PT P  PA +  +E   ++P     T   +  P +    AP  P        E
Sbjct: 561  -------PTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPE 613

Query: 1465 ATSWFSKEEPVTISPFPSLQPLGHNKSRASSSLDGFKDSFDLQGQSTLK---ISNPKGW- 1520
              +  + EEP   +P  +  P    +   ++  +    +      +T K    + PKG  
Sbjct: 614  EPTPTTPEEPAPTTP-KAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTA 672

Query: 1521 -VTFEEEEDFGVKGKSKSACSDLLGNQPSSFSGSNLTLNDDWNKGTNVSFCVLPSRRPPP 1579
              T +E      K  +    +     +P+S +           KGT  +    P+   P 
Sbjct: 673  PTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTP--KGTAPTTPKEPAPTTPK 730

Query: 1580 PPVPLLPPGTSPPV--DPFTTLASKASP 1605
             P P  P GT+P    +P  T   K +P
Sbjct: 731  EPAPTTPKGTAPTTLKEPAPTTPKKPAP 758



 Score = 63.9 bits (154), Expect = 1e-09
 Identities = 73/330 (22%), Positives = 114/330 (34%), Gaps = 55/330 (16%)

Query: 1066 PQHLQPSS-SSGLGTSPSS-SPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSA-QS 1122
            P+ L P++      T+P   +P T    +P   + P P+ P  P+    + P P +  ++
Sbjct: 604  PEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKET 663

Query: 1123 SPIDAQPATPLPQKDPAQPLEPKRPPP------------------PRPVAPP-TRPAPPQ 1163
            +P   +   P   K+PA P  PK+P P                  P P  P  T P  P+
Sbjct: 664  APTTPKGTAPTTLKEPA-PTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPK 722

Query: 1164 RPPP-------PSGARSPAPTRKEFGGIGAPPSPGVARREMEAPKSPGTTRKDNIGRSQP 1216
             P P       P+  +  APT  +      P  P          K P +T  D    + P
Sbjct: 723  EPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTP 782

Query: 1217 SPQAGLAGPGPAGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFL 1276
               A      PA      PT P +     AP           TPE+   T+      T  
Sbjct: 783  KETAPTTPKEPA------PTTPKK----PAP----------TTPETPPPTTSEVSTPTTT 822

Query: 1277 PEPL----KPQAAFPPQSSLPPPAQRLQEPLVP-VAAPMPQSGPQPNLETPPQPPPRSRS 1331
             EP      P  + P  S+ P P      P  P V      +  +P + T  +     R 
Sbjct: 823  KEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERD 882

Query: 1332 SHSLPSEASSQPQVKTNGISDGKRESPLKI 1361
              + P   ++ P++     +  ++ +  KI
Sbjct: 883  LRTTPETTTAAPKMTKETATTTEKTTESKI 912



 Score = 34.3 bits (77), Expect = 1.0
 Identities = 77/406 (18%), Positives = 132/406 (32%), Gaps = 75/406 (18%)

Query: 1137 DPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARS-------------PAPTRKEFGG 1183
            +P  P   K+ PPP   +   +    + P PP+  ++                  +E   
Sbjct: 68   NPTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSS 127

Query: 1184 IGAPPSPGVARREMEAPKSPGTTR-----------KDNIGRSQPSPQAGLAGPGPAGYST 1232
              +  S     R++++ K+    R           K N  + +P+P+  +     +G   
Sbjct: 128  SSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDN 187

Query: 1233 A-------------------------------RPTIPPRAGVISAPQSHARASAGRLTPE 1261
                                            RP++PP     S        +  + T  
Sbjct: 188  GDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPN----SDTSKETSLTVNKETTV 243

Query: 1262 SQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQEPLVPVAAPMPQSGPQ---PN 1318
               +T+ T+K  T      K  +A   QS     A+ L      +A P P++      P 
Sbjct: 244  ETKETTTTNK-QTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPA 302

Query: 1319 LETPPQPPPRSRSSHSLPSE-ASSQPQVKTNGISDGKRESPLKIDPFEDLSFNLLAVSKA 1377
            L TP +P P      + P E AS+ P+  T         +P +  P    S        A
Sbjct: 303  LTTPKEPTP------TTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPA 356

Query: 1378 QLSVQTSPVPTPDPKRLIQLPSATQSNVLSSVSCMPTMPPIPARSQSQENMRSSP-NPFI 1436
              + +  P PT  PK     P+ T+    ++    PT P  PA +  ++   ++P  P  
Sbjct: 357  PTTTK-EPAPT-TPKE--PAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAP 412

Query: 1437 TGLTRTNPFSDRTAAPGNPFRAKSEESEATSWFSKEEPVTISPFPS 1482
            T      P + +  AP     A +   E      K+   T    P+
Sbjct: 413  TTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA 458



 Score = 33.1 bits (74), Expect = 2.2
 Identities = 49/247 (19%), Positives = 86/247 (34%), Gaps = 21/247 (8%)

Query: 1008 KSPDWIKNLEEEMSLEKISIALPSS----------TSSTLLGEDAEVAADFDMEGDVDDY 1057
            KSPD       E+S E    AL +S          T +    E    A D   E D+   
Sbjct: 830  KSPD---ESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRT- 885

Query: 1058 SAEVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVP---SLPIRPSRAPSRT 1114
            + E     P+  + ++++   T+ S    T+   + T ++   P   +     + AP  T
Sbjct: 886  TPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVT 945

Query: 1115 PGPPSAQSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSP 1174
                +  ++ I  +P      KD A   +   P P +P   P +P   ++P      R P
Sbjct: 946  TTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKP 1005

Query: 1175 --APTRKEFGGI--GAPPSPGVARREMEAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAGY 1230
               PT ++         P+  +A   ++    P  T    +    P  +      G   +
Sbjct: 1006 KTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSEDAGGAEGETPH 1065

Query: 1231 STARPTI 1237
               RP +
Sbjct: 1066 MLLRPHV 1072


>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
          Length = 1404

 Score = 96.7 bits (239), Expect = 2e-19
 Identities = 123/533 (23%), Positives = 187/533 (35%), Gaps = 60/533 (11%)

Query: 1079 TSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQPATPLPQKDP 1138
            T+  S+P T    +PT ++ P P+ P  P+   ++ P P + +S+P   +   P   K P
Sbjct: 384  TTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKP 443

Query: 1139 AQPLEPKRPPPPRPVAP----PTRPAPPQRPPPPSGARSPAPTRKEFGGIGAPPSPGVAR 1194
            A P  PK P P  P  P    P  PAP  + P P+  + PAPT        AP  P    
Sbjct: 444  A-PTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPT--------APKKPAPTT 494

Query: 1195 REMEAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAGYSTARPTIPPRAGVISAPQSHARAS 1254
             +  AP +P           +P+P      P P       PT    A   +   +     
Sbjct: 495  PKEPAPTTP----------KEPAPTT-TKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTK 543

Query: 1255 AGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQEPLVPVAAPMPQSG 1314
            +   TP+  S T      +T  P P  P+   P     P P    +        P P + 
Sbjct: 544  SAPTTPKEPSPT------TTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTT 597

Query: 1315 PQPNLETPPQPPPRSRSSHSLPSEASSQPQVKTNGISDGKRESPLKIDPFEDLSFNLLAV 1374
             +P   TP +P P +    + P+            ++    E P    P E      LA 
Sbjct: 598  KKPAPTTPKEPAP-TTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEE------LAP 650

Query: 1375 SKAQLSVQTSPVPTPDPKRLIQLPSATQSNVLSSVSCMPTMPPIPARSQSQENMRSSPNP 1434
            +  +      P PT   +     P A   N     +  PT P  PA +  +E   ++P  
Sbjct: 651  TTPE-----EPTPTTPEEPAPTTPKAAAPNTPKEPA--PTTPKEPAPTTPKEPAPTTPKE 703

Query: 1435 FI-TGLTRTNPFSDRTAAPGNPFRAKSEESEATSWFSKEEPVTISPFPSLQPLGHNKSRA 1493
               T    T P + +  AP  P +   +E   T+           P P+       K  A
Sbjct: 704  TAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTP-----KGTA 758

Query: 1494 SSSLDGFKDSFDLQGQSTLKISNPKGWVTFEEEEDFGVKGKSKSACSDLLGNQPSSFSGS 1553
             ++      +   +   T     PKG      +E      K K A  +L    P++  G 
Sbjct: 759  PTTPKEPAPTTPKEPAPT----TPKGTAPTTLKEPAPTTPK-KPAPKEL---APTTTKGP 810

Query: 1554 NLTLNDDWNKGTNVSFCVLPSRRPPPPPVPLLPPGTSPPVDPFTTLASKASPT 1606
              T +D     T        + + P P  P  P  T+P   P TT +  ++PT
Sbjct: 811  TSTTSDK-PAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTT-SEVSTPT 861



 Score = 70.5 bits (171), Expect = 1e-11
 Identities = 120/568 (21%), Positives = 195/568 (34%), Gaps = 59/568 (10%)

Query: 1065 LPQHLQPSSSSGLGTSPSSS---PRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQ 1121
            LP +   S  + L  +  ++     T+     T ++G   +   + +++  +T     A 
Sbjct: 264  LPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAP 323

Query: 1122 SSPIDAQPATPLPQKDPAQP--LEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRK 1179
            +S + A+P TP  +     P    PK P P  P  P    +   + P P+  +S   T K
Sbjct: 324  TSKVLAKP-TPKAETTTKGPALTTPKEPTPTTPKEP---ASTTPKEPTPTTIKSAPTTPK 379

Query: 1180 EFGGIGAPPSPGVARREMEAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAGYST-ARPTIP 1238
            E       P+P   +     PK P  T       + P   A      PA  +T + PT P
Sbjct: 380  E-------PAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTP 432

Query: 1239 -------PRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSS 1291
                   P+    + P+  A  +    TP +  + + T+K     P P  P+   P    
Sbjct: 433  KEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKE----PAPTTPKEPAPTAPK 488

Query: 1292 LPPPAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSS------HSLPSEASSQPQV 1345
             P P    +        P P +  +P+  TP +P P +  S         P+   S P  
Sbjct: 489  KPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTT 548

Query: 1346 KTNGISDGKRESPLKIDPFEDLSFNLLAVSKAQLSVQTSPVPTPDPKRLIQLPSATQSNV 1405
                 S    + P    P E          K   +    P PT  PK     P+ T+   
Sbjct: 549  PKEP-SPTTTKEPAPTTPKEPAP---TTPKKPAPTTPKEPAPT-TPKE--PAPTTTKKPA 601

Query: 1406 LSSVSCMPTMPPIPARSQSQENMRSSPNPFI-TGLTRTNPFSDRTAAPGNPFRAKSEESE 1464
                   PT P  PA +  +E   ++P     T   +  P +    AP  P        E
Sbjct: 602  -------PTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPE 654

Query: 1465 ATSWFSKEEPVTISPFPSLQPLGHNKSRASSSLDGFKDSFDLQGQSTLK---ISNPKGW- 1520
              +  + EEP   +P  +  P    +   ++  +    +      +T K    + PKG  
Sbjct: 655  EPTPTTPEEPAPTTP-KAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTA 713

Query: 1521 -VTFEEEEDFGVKGKSKSACSDLLGNQPSSFSGSNLTLNDDWNKGTNVSFCVLPSRRPPP 1579
              T +E      K  +    +     +P+S +           KGT  +    P+   P 
Sbjct: 714  PTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTP--KGTAPTTPKEPAPTTPK 771

Query: 1580 PPVPLLPPGTSPPV--DPFTTLASKASP 1605
             P P  P GT+P    +P  T   K +P
Sbjct: 772  EPAPTTPKGTAPTTLKEPAPTTPKKPAP 799



 Score = 63.9 bits (154), Expect = 1e-09
 Identities = 73/330 (22%), Positives = 114/330 (34%), Gaps = 55/330 (16%)

Query: 1066 PQHLQPSS-SSGLGTSPSS-SPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSA-QS 1122
            P+ L P++      T+P   +P T    +P   + P P+ P  P+    + P P +  ++
Sbjct: 645  PEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKET 704

Query: 1123 SPIDAQPATPLPQKDPAQPLEPKRPPP------------------PRPVAPP-TRPAPPQ 1163
            +P   +   P   K+PA P  PK+P P                  P P  P  T P  P+
Sbjct: 705  APTTPKGTAPTTLKEPA-PTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPK 763

Query: 1164 RPPP-------PSGARSPAPTRKEFGGIGAPPSPGVARREMEAPKSPGTTRKDNIGRSQP 1216
             P P       P+  +  APT  +      P  P          K P +T  D    + P
Sbjct: 764  EPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTP 823

Query: 1217 SPQAGLAGPGPAGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFL 1276
               A      PA      PT P +     AP           TPE+   T+      T  
Sbjct: 824  KETAPTTPKEPA------PTTPKK----PAP----------TTPETPPPTTSEVSTPTTT 863

Query: 1277 PEPL----KPQAAFPPQSSLPPPAQRLQEPLVP-VAAPMPQSGPQPNLETPPQPPPRSRS 1331
             EP      P  + P  S+ P P      P  P V      +  +P + T  +     R 
Sbjct: 864  KEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERD 923

Query: 1332 SHSLPSEASSQPQVKTNGISDGKRESPLKI 1361
              + P   ++ P++     +  ++ +  KI
Sbjct: 924  LRTTPETTTAAPKMTKETATTTEKTTESKI 953



 Score = 34.3 bits (77), Expect = 1.0
 Identities = 77/406 (18%), Positives = 132/406 (32%), Gaps = 75/406 (18%)

Query: 1137 DPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARS-------------PAPTRKEFGG 1183
            +P  P   K+ PPP   +   +    + P PP+  ++                  +E   
Sbjct: 109  NPTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSS 168

Query: 1184 IGAPPSPGVARREMEAPKSPGTTR-----------KDNIGRSQPSPQAGLAGPGPAGYST 1232
              +  S     R++++ K+    R           K N  + +P+P+  +     +G   
Sbjct: 169  SSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDN 228

Query: 1233 A-------------------------------RPTIPPRAGVISAPQSHARASAGRLTPE 1261
                                            RP++PP     S        +  + T  
Sbjct: 229  GDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPN----SDTSKETSLTVNKETTV 284

Query: 1262 SQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQEPLVPVAAPMPQSGPQ---PN 1318
               +T+ T+K  T      K  +A   QS     A+ L      +A P P++      P 
Sbjct: 285  ETKETTTTNK-QTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPA 343

Query: 1319 LETPPQPPPRSRSSHSLPSE-ASSQPQVKTNGISDGKRESPLKIDPFEDLSFNLLAVSKA 1377
            L TP +P P      + P E AS+ P+  T         +P +  P    S        A
Sbjct: 344  LTTPKEPTP------TTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPA 397

Query: 1378 QLSVQTSPVPTPDPKRLIQLPSATQSNVLSSVSCMPTMPPIPARSQSQENMRSSP-NPFI 1436
              + +  P PT  PK     P+ T+    ++    PT P  PA +  ++   ++P  P  
Sbjct: 398  PTTTK-EPAPT-TPKE--PAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAP 453

Query: 1437 TGLTRTNPFSDRTAAPGNPFRAKSEESEATSWFSKEEPVTISPFPS 1482
            T      P + +  AP     A +   E      K+   T    P+
Sbjct: 454  TTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA 499



 Score = 33.1 bits (74), Expect = 2.2
 Identities = 49/247 (19%), Positives = 86/247 (34%), Gaps = 21/247 (8%)

Query: 1008 KSPDWIKNLEEEMSLEKISIALPSS----------TSSTLLGEDAEVAADFDMEGDVDDY 1057
            KSPD       E+S E    AL +S          T +    E    A D   E D+   
Sbjct: 871  KSPD---ESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRT- 926

Query: 1058 SAEVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVP---SLPIRPSRAPSRT 1114
            + E     P+  + ++++   T+ S    T+   + T ++   P   +     + AP  T
Sbjct: 927  TPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVT 986

Query: 1115 PGPPSAQSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSP 1174
                +  ++ I  +P      KD A   +   P P +P   P +P   ++P      R P
Sbjct: 987  TTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKP 1046

Query: 1175 --APTRKEFGGI--GAPPSPGVARREMEAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAGY 1230
               PT ++         P+  +A   ++    P  T    +    P  +      G   +
Sbjct: 1047 KTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSEDAGGAEGETPH 1106

Query: 1231 STARPTI 1237
               RP +
Sbjct: 1107 MLLRPHV 1113


>gi|116284392 mucin 2 precursor [Homo sapiens]
          Length = 5179

 Score = 94.7 bits (234), Expect = 6e-19
 Identities = 103/438 (23%), Positives = 141/438 (32%), Gaps = 48/438 (10%)

Query: 1056 DYSAEVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTP 1115
            DY   V    P     ++ S   T+PS  P ++    PT +  P  +    P   P+ TP
Sbjct: 1381 DYKIRVNCCWPMDKCITTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPP--PTTTP 1438

Query: 1116 GPP--SAQSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPP---QRPPPPSG 1170
             PP  +  + P    P+ P+       P     PP   P  P T P+PP      PPP+ 
Sbjct: 1439 SPPITTTTTPPPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTT 1498

Query: 1171 ARSPAPTRKEFGGIGAPPSPGVARREMEAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAGY 1230
              SP  T         PP+          P  P TT       + PSP        P   
Sbjct: 1499 TPSPPTTTPI-----TPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTST 1553

Query: 1231 STARPTI---PPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFP 1287
            +T  PT    PP     + P +   +     TP   + T+ T   +T    P       P
Sbjct: 1554 TTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPP 1613

Query: 1288 PQSSLPPPAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQVKT 1347
            P ++  PP      P        P + P P   T   PPP +  S    +  S      T
Sbjct: 1614 PTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTT 1673

Query: 1348 NGISDGKRESPLKIDPFEDLSFNLLAVSKAQLSVQTSPVPTPDPKRLIQLPSATQSNVLS 1407
                     SP+   P                S  T+ + TP P      P  T +   S
Sbjct: 1674 TPPPTTTPSSPITTTP----------------SPPTTTMTTPSPTTTPSSPITTTTTPSS 1717

Query: 1408 SVSCMPTMPPIPARSQSQENMRSSPNPFITGLTRTNPFSDRTAAPGNPFRAKSEESEATS 1467
            + +  P+ PP    + S     S P   +T L  T   S  T  P  P            
Sbjct: 1718 TTT--PSPPPTTMTTPSPTTTPSPPTTTMTTLPPTTTSSPLTTTPLPP------------ 1763

Query: 1468 WFSKEEPVTISPFPSLQP 1485
                  P T SPF +  P
Sbjct: 1764 ---SITPPTFSPFSTTTP 1778



 Score = 67.4 bits (163), Expect = 1e-10
 Identities = 68/255 (26%), Positives = 87/255 (34%), Gaps = 21/255 (8%)

Query: 1079 TSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQS-SPIDAQPATPLPQKD 1137
            T+P + P ++    PT +  P P+    P   P+ TP PP+  + SP      TP P   
Sbjct: 1544 TTPITPPTSTTTLPPTTTPSPPPTTTTTPP--PTTTPSPPTTTTPSPPTITTTTPPPTTT 1601

Query: 1138 PAQPLEPKRPPPPR--PVAPPTRPAPPQRPP---PPSGARSPAPTRKEFGGIGAPPSPGV 1192
            P+ P      PPP   P  P T P  P       PP+   SP PT          PSP  
Sbjct: 1602 PSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPT 1661

Query: 1193 ARREMEAPKSPGTTRKDNIGRSQPS-PQAGLAGPGPAGYSTARPTIPPRAGVISAPQSHA 1251
                   P  P TT       + PS P      P     +T  PT  P     S+P +  
Sbjct: 1662 TT----TPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTP-----SSPITTT 1712

Query: 1252 RASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQEPLVPVAAPMP 1311
               +   TP     T  T   +T    P       PP ++  P       PL P   P  
Sbjct: 1713 TTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPPTTTSSP---LTTTPLPPSITPPT 1769

Query: 1312 QSGPQPNLETPPQPP 1326
             S       T P  P
Sbjct: 1770 FSPFSTTTPTTPCVP 1784



 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 73/338 (21%), Positives = 117/338 (34%), Gaps = 47/338 (13%)

Query: 1071 PSSSSGLGTSPSSSPRT-SPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQP 1129
            P+ +    T+P ++  T +P  +PT ++ P  + PI  +   + TP P   Q+      P
Sbjct: 4006 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-PITTTTTVTPTPTPTGTQTPT--TTP 4062

Query: 1130 ATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRKEFGGIGAP-P 1188
             T      P       + P   P+   T   P    P P+G ++P  T         P P
Sbjct: 4063 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTPTGTQTPTTTPITTTTTVTPTP 4119

Query: 1189 SPGVARREMEAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAGYSTARPTIP-PRAGVISAP 1247
            +P   +     P +  TT         P+P  G   P     +T     P P       P
Sbjct: 4120 TPTGTQTPTTTPITTTTTVTPT-----PTP-TGTQTPTTTPITTTTTVTPTPTPTGTQTP 4173

Query: 1248 QSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAF--PPQSSLPPPAQRLQEPL-- 1303
             +    +   +TP      ++T   +     P+        PP+SS P  ++    PL  
Sbjct: 4174 TTTPITTTTTVTPTPTPTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTE 4233

Query: 1304 -------VPVAAPMPQSGPQPNLETPPQPPPRSRSSHSL---PSEASSQPQVKTNGISDG 1353
                   +P A  M  + P     + P  P  +   H+L   PS  +S P   T G + G
Sbjct: 4234 STTLLSTLPPAIEMTSTAPP----STPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTG 4289

Query: 1354 KRESPLKIDPFEDLSFNLLAVSKAQLSVQTSPVPTPDP 1391
               +P                S  Q +  ++  PTP P
Sbjct: 4290 SSSAP--------------TPSTVQTTTTSAWTPTPTP 4313



 Score = 44.7 bits (104), Expect = 7e-04
 Identities = 39/148 (26%), Positives = 58/148 (39%), Gaps = 9/148 (6%)

Query: 1066 PQHLQPSSSSGLGTSPSSSPRTSPCQSPT-----ISEGPVPSLPIRPSRAPSRTPGPPSA 1120
            P   Q  +++ + T+ + +P  +P  + T      S  P+  L        S TP    +
Sbjct: 4167 PTGTQTPTTTPITTTTTVTPTPTPTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSRS 4226

Query: 1121 QSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSP--APTR 1178
             SSP+  +  T L    PA  +     PP  P AP T        PPPS   SP   PTR
Sbjct: 4227 TSSPL-TESTTLLSTLPPAIEMT-STAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTR 4284

Query: 1179 KEFGGIGAPPSPGVARREMEAPKSPGTT 1206
                G  + P+P   +    +  +P  T
Sbjct: 4285 GTTTGSSSAPTPSTVQTTTTSAWTPTPT 4312



 Score = 42.0 bits (97), Expect = 0.005
 Identities = 82/435 (18%), Positives = 139/435 (31%), Gaps = 38/435 (8%)

Query: 1071 PSSSSGLGTSPSSSPRT-SPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQP 1129
            P+ +    T+P ++  T +P  +PT ++ P  + PI  +   + TP P   Q+      P
Sbjct: 3822 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-PITTTTTVTPTPTPTGTQTPT--TTP 3878

Query: 1130 ATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRKEFGGIGAP-P 1188
             T      P       + P   P+   T   P    P P+G ++P  T         P P
Sbjct: 3879 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTPTGTQTPTTTPITTTTTVTPTP 3935

Query: 1189 SPGVARREMEAPKSPGTT-------RKDNIGRSQPSPQAGLAGPGPAGYSTARPTIPPRA 1241
            +P   +     P +  TT              + P        P P    T  PT  P  
Sbjct: 3936 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3995

Query: 1242 GVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQE 1301
               +   +      G  TP +   T+ T    T  P P       P  + +         
Sbjct: 3996 TTTTVTPTPT--PTGTQTPTTTPITTTT----TVTPTPTPTGTQTPTTTPITTTTTVTPT 4049

Query: 1302 PLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQVKTNGISDGKRESPLKI 1361
            P  P     P + P     T    P  + +     +  ++   V       G  ++P   
Sbjct: 4050 P-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPTTT 4107

Query: 1362 DPFEDLSFNLLAVSKAQLSVQTSPVPTPDPKRLIQLPSATQSNVLSSVSCMPTMPPIPAR 1421
                  +           +  T+P+ T         P+ TQ+   + ++   T+ P P  
Sbjct: 4108 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 4167

Query: 1422 SQSQENMRS--------SPNPFITGL-------TRTNPFSDRTAAPGNPFRAKSEESEAT 1466
            + +Q    +        +P P  TG        T T P ++ T +   P  +  + S +T
Sbjct: 4168 TGTQTPTTTPITTTTTVTPTPTPTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSRST 4227

Query: 1467 SWFSKEEPVTISPFP 1481
            S    E    +S  P
Sbjct: 4228 SSPLTESTTLLSTLP 4242



 Score = 40.0 bits (92), Expect = 0.018
 Identities = 79/431 (18%), Positives = 136/431 (31%), Gaps = 34/431 (7%)

Query: 1071 PSSSSGLGTSPSSSPRT-SPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQP 1129
            P+ +    T+P ++  T +P  +PT ++ P  + PI  +   + TP P   Q+      P
Sbjct: 1936 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-PITTTTTVTPTPTPTGTQTPT--TTP 1992

Query: 1130 ATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRKEFGGIGAP-P 1188
             T      P       + P   P+   T   P    P P+G ++P  T         P P
Sbjct: 1993 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTPTGTQTPTTTPITTTTTVTPTP 2049

Query: 1189 SPGVARREMEAPKSPGTT-------RKDNIGRSQPSPQAGLAGPGPAGYSTARPTIPPRA 1241
            +P   +     P +  TT              + P        P P    T  PT  P  
Sbjct: 2050 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2109

Query: 1242 GVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQE 1301
               +   +      G  TP +   T+ T    T  P P       P  + +         
Sbjct: 2110 TTTTVTPTPT--PTGTQTPTTTPITTTT----TVTPTPTPTGTQTPTTTPITTTTTVTPT 2163

Query: 1302 PLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQVKTNGISDGKRESPLKI 1361
            P  P     P + P     T    P  + +     +  ++   V       G  ++P   
Sbjct: 2164 P-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPTTT 2221

Query: 1362 DPFEDLSFNLLAVSKAQLSVQTSPVPTPDPKRLIQLPSATQSNVLSSVSCMPTMPPIPAR 1421
                  +           +  T+P+ T         P+ TQ+   + ++   T+ P P  
Sbjct: 2222 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2281

Query: 1422 SQSQ----------ENMRSSPNPFITGLTRTNPFSDRTAAPGNPFRAKSEESEATSWFSK 1471
            + +Q            +  +P P  T    T P +  T     P      ++  T+  + 
Sbjct: 2282 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-TPTGTQTPTTTPITT 2340

Query: 1472 EEPVTISPFPS 1482
               VT +P P+
Sbjct: 2341 TTTVTPTPTPT 2351



 Score = 40.0 bits (92), Expect = 0.018
 Identities = 79/431 (18%), Positives = 136/431 (31%), Gaps = 34/431 (7%)

Query: 1071 PSSSSGLGTSPSSSPRT-SPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQP 1129
            P+ +    T+P ++  T +P  +PT ++ P  + PI  +   + TP P   Q+      P
Sbjct: 2005 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-PITTTTTVTPTPTPTGTQTPT--TTP 2061

Query: 1130 ATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRKEFGGIGAP-P 1188
             T      P       + P   P+   T   P    P P+G ++P  T         P P
Sbjct: 2062 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTPTGTQTPTTTPITTTTTVTPTP 2118

Query: 1189 SPGVARREMEAPKSPGTT-------RKDNIGRSQPSPQAGLAGPGPAGYSTARPTIPPRA 1241
            +P   +     P +  TT              + P        P P    T  PT  P  
Sbjct: 2119 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2178

Query: 1242 GVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQE 1301
               +   +      G  TP +   T+ T    T  P P       P  + +         
Sbjct: 2179 TTTTVTPTPT--PTGTQTPTTTPITTTT----TVTPTPTPTGTQTPTTTPITTTTTVTPT 2232

Query: 1302 PLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQVKTNGISDGKRESPLKI 1361
            P  P     P + P     T    P  + +     +  ++   V       G  ++P   
Sbjct: 2233 P-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPTTT 2290

Query: 1362 DPFEDLSFNLLAVSKAQLSVQTSPVPTPDPKRLIQLPSATQSNVLSSVSCMPTMPPIPAR 1421
                  +           +  T+P+ T         P+ TQ+   + ++   T+ P P  
Sbjct: 2291 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2350

Query: 1422 SQSQ----------ENMRSSPNPFITGLTRTNPFSDRTAAPGNPFRAKSEESEATSWFSK 1471
            + +Q            +  +P P  T    T P +  T     P      ++  T+  + 
Sbjct: 2351 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-TPTGTQTPTTTPITT 2409

Query: 1472 EEPVTISPFPS 1482
               VT +P P+
Sbjct: 2410 TTTVTPTPTPT 2420



 Score = 40.0 bits (92), Expect = 0.018
 Identities = 79/431 (18%), Positives = 136/431 (31%), Gaps = 34/431 (7%)

Query: 1071 PSSSSGLGTSPSSSPRT-SPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQP 1129
            P+ +    T+P ++  T +P  +PT ++ P  + PI  +   + TP P   Q+      P
Sbjct: 2074 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-PITTTTTVTPTPTPTGTQTPT--TTP 2130

Query: 1130 ATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRKEFGGIGAP-P 1188
             T      P       + P   P+   T   P    P P+G ++P  T         P P
Sbjct: 2131 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTPTGTQTPTTTPITTTTTVTPTP 2187

Query: 1189 SPGVARREMEAPKSPGTT-------RKDNIGRSQPSPQAGLAGPGPAGYSTARPTIPPRA 1241
            +P   +     P +  TT              + P        P P    T  PT  P  
Sbjct: 2188 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2247

Query: 1242 GVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQE 1301
               +   +      G  TP +   T+ T    T  P P       P  + +         
Sbjct: 2248 TTTTVTPTPT--PTGTQTPTTTPITTTT----TVTPTPTPTGTQTPTTTPITTTTTVTPT 2301

Query: 1302 PLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQVKTNGISDGKRESPLKI 1361
            P  P     P + P     T    P  + +     +  ++   V       G  ++P   
Sbjct: 2302 P-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPTTT 2359

Query: 1362 DPFEDLSFNLLAVSKAQLSVQTSPVPTPDPKRLIQLPSATQSNVLSSVSCMPTMPPIPAR 1421
                  +           +  T+P+ T         P+ TQ+   + ++   T+ P P  
Sbjct: 2360 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2419

Query: 1422 SQSQ----------ENMRSSPNPFITGLTRTNPFSDRTAAPGNPFRAKSEESEATSWFSK 1471
            + +Q            +  +P P  T    T P +  T     P      ++  T+  + 
Sbjct: 2420 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-TPTGTQTPTTTPITT 2478

Query: 1472 EEPVTISPFPS 1482
               VT +P P+
Sbjct: 2479 TTTVTPTPTPT 2489



 Score = 40.0 bits (92), Expect = 0.018
 Identities = 79/431 (18%), Positives = 136/431 (31%), Gaps = 34/431 (7%)

Query: 1071 PSSSSGLGTSPSSSPRT-SPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQP 1129
            P+ +    T+P ++  T +P  +PT ++ P  + PI  +   + TP P   Q+      P
Sbjct: 2143 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-PITTTTTVTPTPTPTGTQTPT--TTP 2199

Query: 1130 ATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRKEFGGIGAP-P 1188
             T      P       + P   P+   T   P    P P+G ++P  T         P P
Sbjct: 2200 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTPTGTQTPTTTPITTTTTVTPTP 2256

Query: 1189 SPGVARREMEAPKSPGTT-------RKDNIGRSQPSPQAGLAGPGPAGYSTARPTIPPRA 1241
            +P   +     P +  TT              + P        P P    T  PT  P  
Sbjct: 2257 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2316

Query: 1242 GVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQE 1301
               +   +      G  TP +   T+ T    T  P P       P  + +         
Sbjct: 2317 TTTTVTPTPT--PTGTQTPTTTPITTTT----TVTPTPTPTGTQTPTTTPITTTTTVTPT 2370

Query: 1302 PLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQVKTNGISDGKRESPLKI 1361
            P  P     P + P     T    P  + +     +  ++   V       G  ++P   
Sbjct: 2371 P-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPTTT 2428

Query: 1362 DPFEDLSFNLLAVSKAQLSVQTSPVPTPDPKRLIQLPSATQSNVLSSVSCMPTMPPIPAR 1421
                  +           +  T+P+ T         P+ TQ+   + ++   T+ P P  
Sbjct: 2429 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2488

Query: 1422 SQSQ----------ENMRSSPNPFITGLTRTNPFSDRTAAPGNPFRAKSEESEATSWFSK 1471
            + +Q            +  +P P  T    T P +  T     P      ++  T+  + 
Sbjct: 2489 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-TPTGTQTPTTTPITT 2547

Query: 1472 EEPVTISPFPS 1482
               VT +P P+
Sbjct: 2548 TTTVTPTPTPT 2558



 Score = 40.0 bits (92), Expect = 0.018
 Identities = 79/431 (18%), Positives = 136/431 (31%), Gaps = 34/431 (7%)

Query: 1071 PSSSSGLGTSPSSSPRT-SPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQP 1129
            P+ +    T+P ++  T +P  +PT ++ P  + PI  +   + TP P   Q+      P
Sbjct: 2212 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-PITTTTTVTPTPTPTGTQTPT--TTP 2268

Query: 1130 ATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRKEFGGIGAP-P 1188
             T      P       + P   P+   T   P    P P+G ++P  T         P P
Sbjct: 2269 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTPTGTQTPTTTPITTTTTVTPTP 2325

Query: 1189 SPGVARREMEAPKSPGTT-------RKDNIGRSQPSPQAGLAGPGPAGYSTARPTIPPRA 1241
            +P   +     P +  TT              + P        P P    T  PT  P  
Sbjct: 2326 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2385

Query: 1242 GVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQE 1301
               +   +      G  TP +   T+ T    T  P P       P  + +         
Sbjct: 2386 TTTTVTPTPT--PTGTQTPTTTPITTTT----TVTPTPTPTGTQTPTTTPITTTTTVTPT 2439

Query: 1302 PLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQVKTNGISDGKRESPLKI 1361
            P  P     P + P     T    P  + +     +  ++   V       G  ++P   
Sbjct: 2440 P-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPTTT 2497

Query: 1362 DPFEDLSFNLLAVSKAQLSVQTSPVPTPDPKRLIQLPSATQSNVLSSVSCMPTMPPIPAR 1421
                  +           +  T+P+ T         P+ TQ+   + ++   T+ P P  
Sbjct: 2498 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2557

Query: 1422 SQSQ----------ENMRSSPNPFITGLTRTNPFSDRTAAPGNPFRAKSEESEATSWFSK 1471
            + +Q            +  +P P  T    T P +  T     P      ++  T+  + 
Sbjct: 2558 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-TPTGTQTPTTTPITT 2616

Query: 1472 EEPVTISPFPS 1482
               VT +P P+
Sbjct: 2617 TTTVTPTPTPT 2627



 Score = 40.0 bits (92), Expect = 0.018
 Identities = 79/431 (18%), Positives = 136/431 (31%), Gaps = 34/431 (7%)

Query: 1071 PSSSSGLGTSPSSSPRT-SPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQP 1129
            P+ +    T+P ++  T +P  +PT ++ P  + PI  +   + TP P   Q+      P
Sbjct: 2281 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-PITTTTTVTPTPTPTGTQTPT--TTP 2337

Query: 1130 ATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRKEFGGIGAP-P 1188
             T      P       + P   P+   T   P    P P+G ++P  T         P P
Sbjct: 2338 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTPTGTQTPTTTPITTTTTVTPTP 2394

Query: 1189 SPGVARREMEAPKSPGTT-------RKDNIGRSQPSPQAGLAGPGPAGYSTARPTIPPRA 1241
            +P   +     P +  TT              + P        P P    T  PT  P  
Sbjct: 2395 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2454

Query: 1242 GVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQE 1301
               +   +      G  TP +   T+ T    T  P P       P  + +         
Sbjct: 2455 TTTTVTPTPT--PTGTQTPTTTPITTTT----TVTPTPTPTGTQTPTTTPITTTTTVTPT 2508

Query: 1302 PLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQVKTNGISDGKRESPLKI 1361
            P  P     P + P     T    P  + +     +  ++   V       G  ++P   
Sbjct: 2509 P-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPTTT 2566

Query: 1362 DPFEDLSFNLLAVSKAQLSVQTSPVPTPDPKRLIQLPSATQSNVLSSVSCMPTMPPIPAR 1421
                  +           +  T+P+ T         P+ TQ+   + ++   T+ P P  
Sbjct: 2567 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2626

Query: 1422 SQSQ----------ENMRSSPNPFITGLTRTNPFSDRTAAPGNPFRAKSEESEATSWFSK 1471
            + +Q            +  +P P  T    T P +  T     P      ++  T+  + 
Sbjct: 2627 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-TPTGTQTPTTTPITT 2685

Query: 1472 EEPVTISPFPS 1482
               VT +P P+
Sbjct: 2686 TTTVTPTPTPT 2696



 Score = 40.0 bits (92), Expect = 0.018
 Identities = 79/431 (18%), Positives = 136/431 (31%), Gaps = 34/431 (7%)

Query: 1071 PSSSSGLGTSPSSSPRT-SPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQP 1129
            P+ +    T+P ++  T +P  +PT ++ P  + PI  +   + TP P   Q+      P
Sbjct: 2350 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-PITTTTTVTPTPTPTGTQTPT--TTP 2406

Query: 1130 ATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRKEFGGIGAP-P 1188
             T      P       + P   P+   T   P    P P+G ++P  T         P P
Sbjct: 2407 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTPTGTQTPTTTPITTTTTVTPTP 2463

Query: 1189 SPGVARREMEAPKSPGTT-------RKDNIGRSQPSPQAGLAGPGPAGYSTARPTIPPRA 1241
            +P   +     P +  TT              + P        P P    T  PT  P  
Sbjct: 2464 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2523

Query: 1242 GVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQE 1301
               +   +      G  TP +   T+ T    T  P P       P  + +         
Sbjct: 2524 TTTTVTPTPT--PTGTQTPTTTPITTTT----TVTPTPTPTGTQTPTTTPITTTTTVTPT 2577

Query: 1302 PLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQVKTNGISDGKRESPLKI 1361
            P  P     P + P     T    P  + +     +  ++   V       G  ++P   
Sbjct: 2578 P-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPTTT 2635

Query: 1362 DPFEDLSFNLLAVSKAQLSVQTSPVPTPDPKRLIQLPSATQSNVLSSVSCMPTMPPIPAR 1421
                  +           +  T+P+ T         P+ TQ+   + ++   T+ P P  
Sbjct: 2636 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2695

Query: 1422 SQSQ----------ENMRSSPNPFITGLTRTNPFSDRTAAPGNPFRAKSEESEATSWFSK 1471
            + +Q            +  +P P  T    T P +  T     P      ++  T+  + 
Sbjct: 2696 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-TPTGTQTPTTTPITT 2754

Query: 1472 EEPVTISPFPS 1482
               VT +P P+
Sbjct: 2755 TTTVTPTPTPT 2765



 Score = 40.0 bits (92), Expect = 0.018
 Identities = 79/431 (18%), Positives = 136/431 (31%), Gaps = 34/431 (7%)

Query: 1071 PSSSSGLGTSPSSSPRT-SPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQP 1129
            P+ +    T+P ++  T +P  +PT ++ P  + PI  +   + TP P   Q+      P
Sbjct: 2419 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-PITTTTTVTPTPTPTGTQTPT--TTP 2475

Query: 1130 ATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRKEFGGIGAP-P 1188
             T      P       + P   P+   T   P    P P+G ++P  T         P P
Sbjct: 2476 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTPTGTQTPTTTPITTTTTVTPTP 2532

Query: 1189 SPGVARREMEAPKSPGTT-------RKDNIGRSQPSPQAGLAGPGPAGYSTARPTIPPRA 1241
            +P   +     P +  TT              + P        P P    T  PT  P  
Sbjct: 2533 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2592

Query: 1242 GVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQE 1301
               +   +      G  TP +   T+ T    T  P P       P  + +         
Sbjct: 2593 TTTTVTPTPT--PTGTQTPTTTPITTTT----TVTPTPTPTGTQTPTTTPITTTTTVTPT 2646

Query: 1302 PLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQVKTNGISDGKRESPLKI 1361
            P  P     P + P     T    P  + +     +  ++   V       G  ++P   
Sbjct: 2647 P-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPTTT 2704

Query: 1362 DPFEDLSFNLLAVSKAQLSVQTSPVPTPDPKRLIQLPSATQSNVLSSVSCMPTMPPIPAR 1421
                  +           +  T+P+ T         P+ TQ+   + ++   T+ P P  
Sbjct: 2705 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2764

Query: 1422 SQSQ----------ENMRSSPNPFITGLTRTNPFSDRTAAPGNPFRAKSEESEATSWFSK 1471
            + +Q            +  +P P  T    T P +  T     P      ++  T+  + 
Sbjct: 2765 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-TPTGTQTPTTTPITT 2823

Query: 1472 EEPVTISPFPS 1482
               VT +P P+
Sbjct: 2824 TTTVTPTPTPT 2834



 Score = 40.0 bits (92), Expect = 0.018
 Identities = 79/431 (18%), Positives = 136/431 (31%), Gaps = 34/431 (7%)

Query: 1071 PSSSSGLGTSPSSSPRT-SPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQP 1129
            P+ +    T+P ++  T +P  +PT ++ P  + PI  +   + TP P   Q+      P
Sbjct: 2488 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-PITTTTTVTPTPTPTGTQTPT--TTP 2544

Query: 1130 ATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRKEFGGIGAP-P 1188
             T      P       + P   P+   T   P    P P+G ++P  T         P P
Sbjct: 2545 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTPTGTQTPTTTPITTTTTVTPTP 2601

Query: 1189 SPGVARREMEAPKSPGTT-------RKDNIGRSQPSPQAGLAGPGPAGYSTARPTIPPRA 1241
            +P   +     P +  TT              + P        P P    T  PT  P  
Sbjct: 2602 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2661

Query: 1242 GVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQE 1301
               +   +      G  TP +   T+ T    T  P P       P  + +         
Sbjct: 2662 TTTTVTPTPT--PTGTQTPTTTPITTTT----TVTPTPTPTGTQTPTTTPITTTTTVTPT 2715

Query: 1302 PLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQVKTNGISDGKRESPLKI 1361
            P  P     P + P     T    P  + +     +  ++   V       G  ++P   
Sbjct: 2716 P-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPTTT 2773

Query: 1362 DPFEDLSFNLLAVSKAQLSVQTSPVPTPDPKRLIQLPSATQSNVLSSVSCMPTMPPIPAR 1421
                  +           +  T+P+ T         P+ TQ+   + ++   T+ P P  
Sbjct: 2774 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2833

Query: 1422 SQSQ----------ENMRSSPNPFITGLTRTNPFSDRTAAPGNPFRAKSEESEATSWFSK 1471
            + +Q            +  +P P  T    T P +  T     P      ++  T+  + 
Sbjct: 2834 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-TPTGTQTPTTTPITT 2892

Query: 1472 EEPVTISPFPS 1482
               VT +P P+
Sbjct: 2893 TTTVTPTPTPT 2903



 Score = 40.0 bits (92), Expect = 0.018
 Identities = 79/431 (18%), Positives = 136/431 (31%), Gaps = 34/431 (7%)

Query: 1071 PSSSSGLGTSPSSSPRT-SPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQP 1129
            P+ +    T+P ++  T +P  +PT ++ P  + PI  +   + TP P   Q+      P
Sbjct: 2557 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-PITTTTTVTPTPTPTGTQTPT--TTP 2613

Query: 1130 ATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRKEFGGIGAP-P 1188
             T      P       + P   P+   T   P    P P+G ++P  T         P P
Sbjct: 2614 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTPTGTQTPTTTPITTTTTVTPTP 2670

Query: 1189 SPGVARREMEAPKSPGTT-------RKDNIGRSQPSPQAGLAGPGPAGYSTARPTIPPRA 1241
            +P   +     P +  TT              + P        P P    T  PT  P  
Sbjct: 2671 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2730

Query: 1242 GVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQE 1301
               +   +      G  TP +   T+ T    T  P P       P  + +         
Sbjct: 2731 TTTTVTPTPT--PTGTQTPTTTPITTTT----TVTPTPTPTGTQTPTTTPITTTTTVTPT 2784

Query: 1302 PLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQVKTNGISDGKRESPLKI 1361
            P  P     P + P     T    P  + +     +  ++   V       G  ++P   
Sbjct: 2785 P-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPTTT 2842

Query: 1362 DPFEDLSFNLLAVSKAQLSVQTSPVPTPDPKRLIQLPSATQSNVLSSVSCMPTMPPIPAR 1421
                  +           +  T+P+ T         P+ TQ+   + ++   T+ P P  
Sbjct: 2843 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2902

Query: 1422 SQSQ----------ENMRSSPNPFITGLTRTNPFSDRTAAPGNPFRAKSEESEATSWFSK 1471
            + +Q            +  +P P  T    T P +  T     P      ++  T+  + 
Sbjct: 2903 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-TPTGTQTPTTTPITT 2961

Query: 1472 EEPVTISPFPS 1482
               VT +P P+
Sbjct: 2962 TTTVTPTPTPT 2972



 Score = 40.0 bits (92), Expect = 0.018
 Identities = 79/431 (18%), Positives = 136/431 (31%), Gaps = 34/431 (7%)

Query: 1071 PSSSSGLGTSPSSSPRT-SPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQP 1129
            P+ +    T+P ++  T +P  +PT ++ P  + PI  +   + TP P   Q+      P
Sbjct: 2626 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-PITTTTTVTPTPTPTGTQTPT--TTP 2682

Query: 1130 ATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRKEFGGIGAP-P 1188
             T      P       + P   P+   T   P    P P+G ++P  T         P P
Sbjct: 2683 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTPTGTQTPTTTPITTTTTVTPTP 2739

Query: 1189 SPGVARREMEAPKSPGTT-------RKDNIGRSQPSPQAGLAGPGPAGYSTARPTIPPRA 1241
            +P   +     P +  TT              + P        P P    T  PT  P  
Sbjct: 2740 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2799

Query: 1242 GVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQE 1301
               +   +      G  TP +   T+ T    T  P P       P  + +         
Sbjct: 2800 TTTTVTPTPT--PTGTQTPTTTPITTTT----TVTPTPTPTGTQTPTTTPITTTTTVTPT 2853

Query: 1302 PLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQVKTNGISDGKRESPLKI 1361
            P  P     P + P     T    P  + +     +  ++   V       G  ++P   
Sbjct: 2854 P-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPTTT 2911

Query: 1362 DPFEDLSFNLLAVSKAQLSVQTSPVPTPDPKRLIQLPSATQSNVLSSVSCMPTMPPIPAR 1421
                  +           +  T+P+ T         P+ TQ+   + ++   T+ P P  
Sbjct: 2912 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2971

Query: 1422 SQSQ----------ENMRSSPNPFITGLTRTNPFSDRTAAPGNPFRAKSEESEATSWFSK 1471
            + +Q            +  +P P  T    T P +  T     P      ++  T+  + 
Sbjct: 2972 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-TPTGTQTPTTTPITT 3030

Query: 1472 EEPVTISPFPS 1482
               VT +P P+
Sbjct: 3031 TTTVTPTPTPT 3041



 Score = 40.0 bits (92), Expect = 0.018
 Identities = 79/431 (18%), Positives = 136/431 (31%), Gaps = 34/431 (7%)

Query: 1071 PSSSSGLGTSPSSSPRT-SPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQP 1129
            P+ +    T+P ++  T +P  +PT ++ P  + PI  +   + TP P   Q+      P
Sbjct: 2695 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-PITTTTTVTPTPTPTGTQTPT--TTP 2751

Query: 1130 ATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRKEFGGIGAP-P 1188
             T      P       + P   P+   T   P    P P+G ++P  T         P P
Sbjct: 2752 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTPTGTQTPTTTPITTTTTVTPTP 2808

Query: 1189 SPGVARREMEAPKSPGTT-------RKDNIGRSQPSPQAGLAGPGPAGYSTARPTIPPRA 1241
            +P   +     P +  TT              + P        P P    T  PT  P  
Sbjct: 2809 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2868

Query: 1242 GVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQE 1301
               +   +      G  TP +   T+ T    T  P P       P  + +         
Sbjct: 2869 TTTTVTPTPT--PTGTQTPTTTPITTTT----TVTPTPTPTGTQTPTTTPITTTTTVTPT 2922

Query: 1302 PLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQVKTNGISDGKRESPLKI 1361
            P  P     P + P     T    P  + +     +  ++   V       G  ++P   
Sbjct: 2923 P-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPTTT 2980

Query: 1362 DPFEDLSFNLLAVSKAQLSVQTSPVPTPDPKRLIQLPSATQSNVLSSVSCMPTMPPIPAR 1421
                  +           +  T+P+ T         P+ TQ+   + ++   T+ P P  
Sbjct: 2981 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3040

Query: 1422 SQSQ----------ENMRSSPNPFITGLTRTNPFSDRTAAPGNPFRAKSEESEATSWFSK 1471
            + +Q            +  +P P  T    T P +  T     P      ++  T+  + 
Sbjct: 3041 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-TPTGTQTPTTTPITT 3099

Query: 1472 EEPVTISPFPS 1482
               VT +P P+
Sbjct: 3100 TTTVTPTPTPT 3110



 Score = 40.0 bits (92), Expect = 0.018
 Identities = 79/431 (18%), Positives = 136/431 (31%), Gaps = 34/431 (7%)

Query: 1071 PSSSSGLGTSPSSSPRT-SPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQP 1129
            P+ +    T+P ++  T +P  +PT ++ P  + PI  +   + TP P   Q+      P
Sbjct: 2764 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-PITTTTTVTPTPTPTGTQTPT--TTP 2820

Query: 1130 ATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRKEFGGIGAP-P 1188
             T      P       + P   P+   T   P    P P+G ++P  T         P P
Sbjct: 2821 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTPTGTQTPTTTPITTTTTVTPTP 2877

Query: 1189 SPGVARREMEAPKSPGTT-------RKDNIGRSQPSPQAGLAGPGPAGYSTARPTIPPRA 1241
            +P   +     P +  TT              + P        P P    T  PT  P  
Sbjct: 2878 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2937

Query: 1242 GVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQE 1301
               +   +      G  TP +   T+ T    T  P P       P  + +         
Sbjct: 2938 TTTTVTPTPT--PTGTQTPTTTPITTTT----TVTPTPTPTGTQTPTTTPITTTTTVTPT 2991

Query: 1302 PLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQVKTNGISDGKRESPLKI 1361
            P  P     P + P     T    P  + +     +  ++   V       G  ++P   
Sbjct: 2992 P-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPTTT 3049

Query: 1362 DPFEDLSFNLLAVSKAQLSVQTSPVPTPDPKRLIQLPSATQSNVLSSVSCMPTMPPIPAR 1421
                  +           +  T+P+ T         P+ TQ+   + ++   T+ P P  
Sbjct: 3050 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3109

Query: 1422 SQSQ----------ENMRSSPNPFITGLTRTNPFSDRTAAPGNPFRAKSEESEATSWFSK 1471
            + +Q            +  +P P  T    T P +  T     P      ++  T+  + 
Sbjct: 3110 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-TPTGTQTPTTTPITT 3168

Query: 1472 EEPVTISPFPS 1482
               VT +P P+
Sbjct: 3169 TTTVTPTPTPT 3179



 Score = 40.0 bits (92), Expect = 0.018
 Identities = 79/431 (18%), Positives = 136/431 (31%), Gaps = 34/431 (7%)

Query: 1071 PSSSSGLGTSPSSSPRT-SPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQP 1129
            P+ +    T+P ++  T +P  +PT ++ P  + PI  +   + TP P   Q+      P
Sbjct: 2833 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-PITTTTTVTPTPTPTGTQTPT--TTP 2889

Query: 1130 ATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRKEFGGIGAP-P 1188
             T      P       + P   P+   T   P    P P+G ++P  T         P P
Sbjct: 2890 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTPTGTQTPTTTPITTTTTVTPTP 2946

Query: 1189 SPGVARREMEAPKSPGTT-------RKDNIGRSQPSPQAGLAGPGPAGYSTARPTIPPRA 1241
            +P   +     P +  TT              + P        P P    T  PT  P  
Sbjct: 2947 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3006

Query: 1242 GVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQE 1301
               +   +      G  TP +   T+ T    T  P P       P  + +         
Sbjct: 3007 TTTTVTPTPT--PTGTQTPTTTPITTTT----TVTPTPTPTGTQTPTTTPITTTTTVTPT 3060

Query: 1302 PLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQVKTNGISDGKRESPLKI 1361
            P  P     P + P     T    P  + +     +  ++   V       G  ++P   
Sbjct: 3061 P-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPTTT 3118

Query: 1362 DPFEDLSFNLLAVSKAQLSVQTSPVPTPDPKRLIQLPSATQSNVLSSVSCMPTMPPIPAR 1421
                  +           +  T+P+ T         P+ TQ+   + ++   T+ P P  
Sbjct: 3119 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3178

Query: 1422 SQSQ----------ENMRSSPNPFITGLTRTNPFSDRTAAPGNPFRAKSEESEATSWFSK 1471
            + +Q            +  +P P  T    T P +  T     P      ++  T+  + 
Sbjct: 3179 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-TPTGTQTPTTTPITT 3237

Query: 1472 EEPVTISPFPS 1482
               VT +P P+
Sbjct: 3238 TTTVTPTPTPT 3248



 Score = 40.0 bits (92), Expect = 0.018
 Identities = 79/431 (18%), Positives = 136/431 (31%), Gaps = 34/431 (7%)

Query: 1071 PSSSSGLGTSPSSSPRT-SPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQP 1129
            P+ +    T+P ++  T +P  +PT ++ P  + PI  +   + TP P   Q+      P
Sbjct: 2902 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-PITTTTTVTPTPTPTGTQTPT--TTP 2958

Query: 1130 ATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRKEFGGIGAP-P 1188
             T      P       + P   P+   T   P    P P+G ++P  T         P P
Sbjct: 2959 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTPTGTQTPTTTPITTTTTVTPTP 3015

Query: 1189 SPGVARREMEAPKSPGTT-------RKDNIGRSQPSPQAGLAGPGPAGYSTARPTIPPRA 1241
            +P   +     P +  TT              + P        P P    T  PT  P  
Sbjct: 3016 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3075

Query: 1242 GVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQE 1301
               +   +      G  TP +   T+ T    T  P P       P  + +         
Sbjct: 3076 TTTTVTPTPT--PTGTQTPTTTPITTTT----TVTPTPTPTGTQTPTTTPITTTTTVTPT 3129

Query: 1302 PLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQVKTNGISDGKRESPLKI 1361
            P  P     P + P     T    P  + +     +  ++   V       G  ++P   
Sbjct: 3130 P-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPTTT 3187

Query: 1362 DPFEDLSFNLLAVSKAQLSVQTSPVPTPDPKRLIQLPSATQSNVLSSVSCMPTMPPIPAR 1421
                  +           +  T+P+ T         P+ TQ+   + ++   T+ P P  
Sbjct: 3188 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3247

Query: 1422 SQSQ----------ENMRSSPNPFITGLTRTNPFSDRTAAPGNPFRAKSEESEATSWFSK 1471
            + +Q            +  +P P  T    T P +  T     P      ++  T+  + 
Sbjct: 3248 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-TPTGTQTPTTTPITT 3306

Query: 1472 EEPVTISPFPS 1482
               VT +P P+
Sbjct: 3307 TTTVTPTPTPT 3317



 Score = 40.0 bits (92), Expect = 0.018
 Identities = 79/431 (18%), Positives = 136/431 (31%), Gaps = 34/431 (7%)

Query: 1071 PSSSSGLGTSPSSSPRT-SPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQP 1129
            P+ +    T+P ++  T +P  +PT ++ P  + PI  +   + TP P   Q+      P
Sbjct: 2971 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-PITTTTTVTPTPTPTGTQTPT--TTP 3027

Query: 1130 ATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRKEFGGIGAP-P 1188
             T      P       + P   P+   T   P    P P+G ++P  T         P P
Sbjct: 3028 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTPTGTQTPTTTPITTTTTVTPTP 3084

Query: 1189 SPGVARREMEAPKSPGTT-------RKDNIGRSQPSPQAGLAGPGPAGYSTARPTIPPRA 1241
            +P   +     P +  TT              + P        P P    T  PT  P  
Sbjct: 3085 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3144

Query: 1242 GVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQE 1301
               +   +      G  TP +   T+ T    T  P P       P  + +         
Sbjct: 3145 TTTTVTPTPT--PTGTQTPTTTPITTTT----TVTPTPTPTGTQTPTTTPITTTTTVTPT 3198

Query: 1302 PLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQVKTNGISDGKRESPLKI 1361
            P  P     P + P     T    P  + +     +  ++   V       G  ++P   
Sbjct: 3199 P-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPTTT 3256

Query: 1362 DPFEDLSFNLLAVSKAQLSVQTSPVPTPDPKRLIQLPSATQSNVLSSVSCMPTMPPIPAR 1421
                  +           +  T+P+ T         P+ TQ+   + ++   T+ P P  
Sbjct: 3257 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3316

Query: 1422 SQSQ----------ENMRSSPNPFITGLTRTNPFSDRTAAPGNPFRAKSEESEATSWFSK 1471
            + +Q            +  +P P  T    T P +  T     P      ++  T+  + 
Sbjct: 3317 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-TPTGTQTPTTTPITT 3375

Query: 1472 EEPVTISPFPS 1482
               VT +P P+
Sbjct: 3376 TTTVTPTPTPT 3386



 Score = 40.0 bits (92), Expect = 0.018
 Identities = 79/431 (18%), Positives = 136/431 (31%), Gaps = 34/431 (7%)

Query: 1071 PSSSSGLGTSPSSSPRT-SPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQP 1129
            P+ +    T+P ++  T +P  +PT ++ P  + PI  +   + TP P   Q+      P
Sbjct: 3040 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-PITTTTTVTPTPTPTGTQTPT--TTP 3096

Query: 1130 ATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRKEFGGIGAP-P 1188
             T      P       + P   P+   T   P    P P+G ++P  T         P P
Sbjct: 3097 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTPTGTQTPTTTPITTTTTVTPTP 3153

Query: 1189 SPGVARREMEAPKSPGTT-------RKDNIGRSQPSPQAGLAGPGPAGYSTARPTIPPRA 1241
            +P   +     P +  TT              + P        P P    T  PT  P  
Sbjct: 3154 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3213

Query: 1242 GVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQE 1301
               +   +      G  TP +   T+ T    T  P P       P  + +         
Sbjct: 3214 TTTTVTPTPT--PTGTQTPTTTPITTTT----TVTPTPTPTGTQTPTTTPITTTTTVTPT 3267

Query: 1302 PLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQVKTNGISDGKRESPLKI 1361
            P  P     P + P     T    P  + +     +  ++   V       G  ++P   
Sbjct: 3268 P-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPTTT 3325

Query: 1362 DPFEDLSFNLLAVSKAQLSVQTSPVPTPDPKRLIQLPSATQSNVLSSVSCMPTMPPIPAR 1421
                  +           +  T+P+ T         P+ TQ+   + ++   T+ P P  
Sbjct: 3326 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3385

Query: 1422 SQSQ----------ENMRSSPNPFITGLTRTNPFSDRTAAPGNPFRAKSEESEATSWFSK 1471
            + +Q            +  +P P  T    T P +  T     P      ++  T+  + 
Sbjct: 3386 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-TPTGTQTPTTTPITT 3444

Query: 1472 EEPVTISPFPS 1482
               VT +P P+
Sbjct: 3445 TTTVTPTPTPT 3455



 Score = 40.0 bits (92), Expect = 0.018
 Identities = 79/431 (18%), Positives = 136/431 (31%), Gaps = 34/431 (7%)

Query: 1071 PSSSSGLGTSPSSSPRT-SPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQP 1129
            P+ +    T+P ++  T +P  +PT ++ P  + PI  +   + TP P   Q+      P
Sbjct: 3109 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-PITTTTTVTPTPTPTGTQTPT--TTP 3165

Query: 1130 ATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRKEFGGIGAP-P 1188
             T      P       + P   P+   T   P    P P+G ++P  T         P P
Sbjct: 3166 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTPTGTQTPTTTPITTTTTVTPTP 3222

Query: 1189 SPGVARREMEAPKSPGTT-------RKDNIGRSQPSPQAGLAGPGPAGYSTARPTIPPRA 1241
            +P   +     P +  TT              + P        P P    T  PT  P  
Sbjct: 3223 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3282

Query: 1242 GVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQE 1301
               +   +      G  TP +   T+ T    T  P P       P  + +         
Sbjct: 3283 TTTTVTPTPT--PTGTQTPTTTPITTTT----TVTPTPTPTGTQTPTTTPITTTTTVTPT 3336

Query: 1302 PLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQVKTNGISDGKRESPLKI 1361
            P  P     P + P     T    P  + +     +  ++   V       G  ++P   
Sbjct: 3337 P-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPTTT 3394

Query: 1362 DPFEDLSFNLLAVSKAQLSVQTSPVPTPDPKRLIQLPSATQSNVLSSVSCMPTMPPIPAR 1421
                  +           +  T+P+ T         P+ TQ+   + ++   T+ P P  
Sbjct: 3395 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3454

Query: 1422 SQSQ----------ENMRSSPNPFITGLTRTNPFSDRTAAPGNPFRAKSEESEATSWFSK 1471
            + +Q            +  +P P  T    T P +  T     P      ++  T+  + 
Sbjct: 3455 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-TPTGTQTPTTTPITT 3513

Query: 1472 EEPVTISPFPS 1482
               VT +P P+
Sbjct: 3514 TTTVTPTPTPT 3524



 Score = 40.0 bits (92), Expect = 0.018
 Identities = 79/431 (18%), Positives = 136/431 (31%), Gaps = 34/431 (7%)

Query: 1071 PSSSSGLGTSPSSSPRT-SPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQP 1129
            P+ +    T+P ++  T +P  +PT ++ P  + PI  +   + TP P   Q+      P
Sbjct: 3178 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-PITTTTTVTPTPTPTGTQTPT--TTP 3234

Query: 1130 ATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRKEFGGIGAP-P 1188
             T      P       + P   P+   T   P    P P+G ++P  T         P P
Sbjct: 3235 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTPTGTQTPTTTPITTTTTVTPTP 3291

Query: 1189 SPGVARREMEAPKSPGTT-------RKDNIGRSQPSPQAGLAGPGPAGYSTARPTIPPRA 1241
            +P   +     P +  TT              + P        P P    T  PT  P  
Sbjct: 3292 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3351

Query: 1242 GVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQE 1301
               +   +      G  TP +   T+ T    T  P P       P  + +         
Sbjct: 3352 TTTTVTPTPT--PTGTQTPTTTPITTTT----TVTPTPTPTGTQTPTTTPITTTTTVTPT 3405

Query: 1302 PLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQVKTNGISDGKRESPLKI 1361
            P  P     P + P     T    P  + +     +  ++   V       G  ++P   
Sbjct: 3406 P-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPTTT 3463

Query: 1362 DPFEDLSFNLLAVSKAQLSVQTSPVPTPDPKRLIQLPSATQSNVLSSVSCMPTMPPIPAR 1421
                  +           +  T+P+ T         P+ TQ+   + ++   T+ P P  
Sbjct: 3464 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3523

Query: 1422 SQSQ----------ENMRSSPNPFITGLTRTNPFSDRTAAPGNPFRAKSEESEATSWFSK 1471
            + +Q            +  +P P  T    T P +  T     P      ++  T+  + 
Sbjct: 3524 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-TPTGTQTPTTTPITT 3582

Query: 1472 EEPVTISPFPS 1482
               VT +P P+
Sbjct: 3583 TTTVTPTPTPT 3593



 Score = 40.0 bits (92), Expect = 0.018
 Identities = 79/431 (18%), Positives = 136/431 (31%), Gaps = 34/431 (7%)

Query: 1071 PSSSSGLGTSPSSSPRT-SPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQP 1129
            P+ +    T+P ++  T +P  +PT ++ P  + PI  +   + TP P   Q+      P
Sbjct: 3247 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-PITTTTTVTPTPTPTGTQTPT--TTP 3303

Query: 1130 ATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRKEFGGIGAP-P 1188
             T      P       + P   P+   T   P    P P+G ++P  T         P P
Sbjct: 3304 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTPTGTQTPTTTPITTTTTVTPTP 3360

Query: 1189 SPGVARREMEAPKSPGTT-------RKDNIGRSQPSPQAGLAGPGPAGYSTARPTIPPRA 1241
            +P   +     P +  TT              + P        P P    T  PT  P  
Sbjct: 3361 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3420

Query: 1242 GVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQE 1301
               +   +      G  TP +   T+ T    T  P P       P  + +         
Sbjct: 3421 TTTTVTPTPT--PTGTQTPTTTPITTTT----TVTPTPTPTGTQTPTTTPITTTTTVTPT 3474

Query: 1302 PLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQVKTNGISDGKRESPLKI 1361
            P  P     P + P     T    P  + +     +  ++   V       G  ++P   
Sbjct: 3475 P-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPTTT 3532

Query: 1362 DPFEDLSFNLLAVSKAQLSVQTSPVPTPDPKRLIQLPSATQSNVLSSVSCMPTMPPIPAR 1421
                  +           +  T+P+ T         P+ TQ+   + ++   T+ P P  
Sbjct: 3533 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3592

Query: 1422 SQSQ----------ENMRSSPNPFITGLTRTNPFSDRTAAPGNPFRAKSEESEATSWFSK 1471
            + +Q            +  +P P  T    T P +  T     P      ++  T+  + 
Sbjct: 3593 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-TPTGTQTPTTTPITT 3651

Query: 1472 EEPVTISPFPS 1482
               VT +P P+
Sbjct: 3652 TTTVTPTPTPT 3662



 Score = 40.0 bits (92), Expect = 0.018
 Identities = 79/431 (18%), Positives = 136/431 (31%), Gaps = 34/431 (7%)

Query: 1071 PSSSSGLGTSPSSSPRT-SPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQP 1129
            P+ +    T+P ++  T +P  +PT ++ P  + PI  +   + TP P   Q+      P
Sbjct: 3316 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-PITTTTTVTPTPTPTGTQTPT--TTP 3372

Query: 1130 ATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRKEFGGIGAP-P 1188
             T      P       + P   P+   T   P    P P+G ++P  T         P P
Sbjct: 3373 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTPTGTQTPTTTPITTTTTVTPTP 3429

Query: 1189 SPGVARREMEAPKSPGTT-------RKDNIGRSQPSPQAGLAGPGPAGYSTARPTIPPRA 1241
            +P   +     P +  TT              + P        P P    T  PT  P  
Sbjct: 3430 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3489

Query: 1242 GVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQE 1301
               +   +      G  TP +   T+ T    T  P P       P  + +         
Sbjct: 3490 TTTTVTPTPT--PTGTQTPTTTPITTTT----TVTPTPTPTGTQTPTTTPITTTTTVTPT 3543

Query: 1302 PLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQVKTNGISDGKRESPLKI 1361
            P  P     P + P     T    P  + +     +  ++   V       G  ++P   
Sbjct: 3544 P-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPTTT 3601

Query: 1362 DPFEDLSFNLLAVSKAQLSVQTSPVPTPDPKRLIQLPSATQSNVLSSVSCMPTMPPIPAR 1421
                  +           +  T+P+ T         P+ TQ+   + ++   T+ P P  
Sbjct: 3602 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3661

Query: 1422 SQSQ----------ENMRSSPNPFITGLTRTNPFSDRTAAPGNPFRAKSEESEATSWFSK 1471
            + +Q            +  +P P  T    T P +  T     P      ++  T+  + 
Sbjct: 3662 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-TPTGTQTPTTTPITT 3720

Query: 1472 EEPVTISPFPS 1482
               VT +P P+
Sbjct: 3721 TTTVTPTPTPT 3731



 Score = 40.0 bits (92), Expect = 0.018
 Identities = 79/431 (18%), Positives = 136/431 (31%), Gaps = 34/431 (7%)

Query: 1071 PSSSSGLGTSPSSSPRT-SPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQP 1129
            P+ +    T+P ++  T +P  +PT ++ P  + PI  +   + TP P   Q+      P
Sbjct: 3385 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-PITTTTTVTPTPTPTGTQTPT--TTP 3441

Query: 1130 ATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRKEFGGIGAP-P 1188
             T      P       + P   P+   T   P    P P+G ++P  T         P P
Sbjct: 3442 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTPTGTQTPTTTPITTTTTVTPTP 3498

Query: 1189 SPGVARREMEAPKSPGTT-------RKDNIGRSQPSPQAGLAGPGPAGYSTARPTIPPRA 1241
            +P   +     P +  TT              + P        P P    T  PT  P  
Sbjct: 3499 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3558

Query: 1242 GVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQE 1301
               +   +      G  TP +   T+ T    T  P P       P  + +         
Sbjct: 3559 TTTTVTPTPT--PTGTQTPTTTPITTTT----TVTPTPTPTGTQTPTTTPITTTTTVTPT 3612

Query: 1302 PLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQVKTNGISDGKRESPLKI 1361
            P  P     P + P     T    P  + +     +  ++   V       G  ++P   
Sbjct: 3613 P-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPTTT 3670

Query: 1362 DPFEDLSFNLLAVSKAQLSVQTSPVPTPDPKRLIQLPSATQSNVLSSVSCMPTMPPIPAR 1421
                  +           +  T+P+ T         P+ TQ+   + ++   T+ P P  
Sbjct: 3671 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3730

Query: 1422 SQSQ----------ENMRSSPNPFITGLTRTNPFSDRTAAPGNPFRAKSEESEATSWFSK 1471
            + +Q            +  +P P  T    T P +  T     P      ++  T+  + 
Sbjct: 3731 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-TPTGTQTPTTTPITT 3789

Query: 1472 EEPVTISPFPS 1482
               VT +P P+
Sbjct: 3790 TTTVTPTPTPT 3800



 Score = 40.0 bits (92), Expect = 0.018
 Identities = 79/431 (18%), Positives = 136/431 (31%), Gaps = 34/431 (7%)

Query: 1071 PSSSSGLGTSPSSSPRT-SPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQP 1129
            P+ +    T+P ++  T +P  +PT ++ P  + PI  +   + TP P   Q+      P
Sbjct: 3454 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-PITTTTTVTPTPTPTGTQTPT--TTP 3510

Query: 1130 ATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRKEFGGIGAP-P 1188
             T      P       + P   P+   T   P    P P+G ++P  T         P P
Sbjct: 3511 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTPTGTQTPTTTPITTTTTVTPTP 3567

Query: 1189 SPGVARREMEAPKSPGTT-------RKDNIGRSQPSPQAGLAGPGPAGYSTARPTIPPRA 1241
            +P   +     P +  TT              + P        P P    T  PT  P  
Sbjct: 3568 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3627

Query: 1242 GVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQE 1301
               +   +      G  TP +   T+ T    T  P P       P  + +         
Sbjct: 3628 TTTTVTPTPT--PTGTQTPTTTPITTTT----TVTPTPTPTGTQTPTTTPITTTTTVTPT 3681

Query: 1302 PLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQVKTNGISDGKRESPLKI 1361
            P  P     P + P     T    P  + +     +  ++   V       G  ++P   
Sbjct: 3682 P-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPTTT 3739

Query: 1362 DPFEDLSFNLLAVSKAQLSVQTSPVPTPDPKRLIQLPSATQSNVLSSVSCMPTMPPIPAR 1421
                  +           +  T+P+ T         P+ TQ+   + ++   T+ P P  
Sbjct: 3740 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3799

Query: 1422 SQSQ----------ENMRSSPNPFITGLTRTNPFSDRTAAPGNPFRAKSEESEATSWFSK 1471
            + +Q            +  +P P  T    T P +  T     P      ++  T+  + 
Sbjct: 3800 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-TPTGTQTPTTTPITT 3858

Query: 1472 EEPVTISPFPS 1482
               VT +P P+
Sbjct: 3859 TTTVTPTPTPT 3869



 Score = 38.1 bits (87), Expect = 0.069
 Identities = 79/410 (19%), Positives = 128/410 (31%), Gaps = 36/410 (8%)

Query: 1094 TISEGPVP--SLPIRPSRAPSRTPGPPSAQSSPIDAQPATPLPQKDPAQPLEPKRPPPPR 1151
            T +E P P  + PI  +   + TP P   Q+      P T      P       + P   
Sbjct: 1888 TTTENPTPPTTTPITTTTTVTPTPTPTGTQTP--TTTPITTTTTVTPTPTPTGTQTPTTT 1945

Query: 1152 PVAPPTRPAPPQRPPPPSGARSPAPTRKEFGGIGAP-PSPGVARREMEAPKSPGTT---- 1206
            P+   T   P    P P+G ++P  T         P P+P   +     P +  TT    
Sbjct: 1946 PITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2002

Query: 1207 ---RKDNIGRSQPSPQAGLAGPGPAGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQ 1263
                      + P        P P    T  PT  P     +   +      G  TP + 
Sbjct: 2003 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV--TPTPTPTGTQTPTTT 2060

Query: 1264 SKTSETSKGSTFLPEPLKPQAAFPPQSS-----LPPPAQRLQEPLVPVAAPMPQS-GPQP 1317
              T+ T+   T  P   +     P  ++      P P         P+      +  P P
Sbjct: 2061 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2120

Query: 1318 NLETPPQPPPRSRSSHSLPSEASSQPQV-KTNGISDGKRESPLKIDPFEDLSFNLLAVSK 1376
                 P   P + ++   P+   +  Q   T  I+     +P                + 
Sbjct: 2121 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT------GTQTPTT 2174

Query: 1377 AQLSVQTSPVPTPDPKRLIQLPSATQSNVLSSVSCMP----TMPPIPARSQSQENMRSSP 1432
              ++  T+  PTP P    Q P+ T     ++V+  P    T  P      +   +  +P
Sbjct: 2175 TPITTTTTVTPTPTPTG-TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2233

Query: 1433 NPFITGLTRTNPFSDRTAAPGNPFRAKSEESEATSWFSKEEPVTISPFPS 1482
             P  T    T P +  T     P      ++  T+  +    VT +P P+
Sbjct: 2234 TPTGTQTPTTTPITTTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTPTPT 2282



 Score = 38.1 bits (87), Expect = 0.069
 Identities = 55/235 (23%), Positives = 83/235 (35%), Gaps = 28/235 (11%)

Query: 1071 PSSSSGLGTSPSSSPRT-SPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQS---SPID 1126
            P+ +    T+P ++  T +P  +PT ++ P  + PI  +   + TP P   Q+   +PI 
Sbjct: 4121 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-PITTTTTVTPTPTPTGTQTPTTTPIT 4179

Query: 1127 AQPA-TPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRKEFGGIG 1185
                 TP P     Q   P       P+A  T   PP     P  +RS +    E   + 
Sbjct: 4180 TTTTVTPTPTPTGTQTGPPTHTSTA-PIAELTTSNPPPESSTPQTSRSTSSPLTESTTLL 4238

Query: 1186 APPSPGVARREMEAPKSPGTTRKDNIGRS-QPSPQAGLAGPGPAGYSTARPTIPPRAGVI 1244
            +   P +       P +P      + G +  P P    + PG        PT     G  
Sbjct: 4239 STLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPG-------TPTRGTTTGSS 4291

Query: 1245 SAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRL 1299
            SAP           TP +   T  T+   T  P PL   +        P P+  L
Sbjct: 4292 SAP-----------TPSTVQTT--TTSAWTPTPTPLSTPSIIRTTGLRPYPSSVL 4333



 Score = 35.4 bits (80), Expect = 0.45
 Identities = 32/95 (33%), Positives = 39/95 (41%), Gaps = 18/95 (18%)

Query: 1071 PSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQPA 1130
            PSS     T+PSS+  T+P   PT    P P+    P    + T  PP+  SSP+     
Sbjct: 1705 PSSPITTTTTPSST--TTPSPPPTTMTTPSPTTTPSPP-TTTMTTLPPTTTSSPL---TT 1758

Query: 1131 TPLPQKDPAQPLEPKRPPP---PRPVAPPTRPAPP 1162
            TPLP         P   PP   P     PT P  P
Sbjct: 1759 TPLP---------PSITPPTFSPFSTTTPTTPCVP 1784



 Score = 32.0 bits (71), Expect = 5.0
 Identities = 13/38 (34%), Positives = 21/38 (55%), Gaps = 4/38 (10%)

Query: 1129 PATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPP 1166
            P+TP P   P++      P P +P + P++P P  +PP
Sbjct: 4377 PSTPSPTPTPSK----STPTPSKPSSTPSKPTPGTKPP 4410


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 94.0 bits (232), Expect = 1e-18
 Identities = 136/585 (23%), Positives = 196/585 (33%), Gaps = 104/585 (17%)

Query: 1066 PQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEG-----PVPSLPIRPSRAPSR------T 1114
            P    PS   GL T P     T+P  +P   +G     P    P  P+  P        T
Sbjct: 1129 PAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLAT 1188

Query: 1115 PGPPSAQSSPIDAQP------ATPLPQKDPAQPL-------------EPKRPPPPRPVAP 1155
            P P  A ++P    P      ATP P+  P  P               PK  P      P
Sbjct: 1189 PSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATP 1248

Query: 1156 PTRPAPPQRPPPPSGARSPAPTRKEF-GGIGAPPSPGVARREMEAPKSPGTTRKDNIGRS 1214
            P+    P  PPP      PA T     GG+  PP  G     +  P SP      +  + 
Sbjct: 1249 PSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKG 1308

Query: 1215 QPSPQAGLAGPGPAGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGST 1274
             P+P A    P P G     P  PP  G  + P     +  G  TP +   T+ +SKG  
Sbjct: 1309 APTPPAA-TPPSPKG----SPGTPPPKGAPTPPAVTPPSPKG--TP-TLPATTPSSKGG- 1359

Query: 1275 FLPEPLKPQAAFPPQSSLPPPAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHS 1334
                P  P +   P      P+ +    + P   P P+ GP   + +P   P        
Sbjct: 1360 ----PTTPSSKEGPTPPAATPSHKGGPAMTP---PSPKRGPA--IPSPKGDPTSPAVIPL 1410

Query: 1335 LPSEASSQPQVKTNGISDGKRE-SPLKIDPFEDLSFNLLAVSKAQLSVQTSPVP-TPDPK 1392
             P +A + P  +    +  K + +P  + P        +++ KA  +      P TP  K
Sbjct: 1411 SPKKAPATPVTREGAATPSKGDLTPPAVTP--------VSLKKAPATSAPKGGPATPSSK 1462

Query: 1393 RLIQLPSATQSNVLSSVSCMPTMPPIP---ARSQSQENMRSSPNPFITGLTRTNPFSDRT 1449
                LP+ T  +        P  PP P   A S S +   ++P P           S   
Sbjct: 1463 GDPTLPAVTPPS--------PKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPK 1514

Query: 1450 AAPGNPFRAKSEESEATSWFSKEEPVTISPFPSLQPLGHNKSRASSSLDGFKDSFDLQGQ 1509
              P  P   +   +   +  SK+ P T++P  +L P                        
Sbjct: 1515 EVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIP------------------------ 1550

Query: 1510 STLKISNPKGWVTFEEEEDFGVKGKSKSACSDLLGNQPSSFSGS----NLTLNDDWNKGT 1565
              + + +PK        ++      SK A S      PS++ G+     L +       +
Sbjct: 1551 PAMTVPSPKKTPAIPTPKEAPATPSSKEASSP-PAVTPSTYKGAPSPKELLIPPAVTSPS 1609

Query: 1566 NVSFCVLPSRRPPPP---PVPLLPPG--TSPPVDPFTTLASKASP 1605
                   P+  PP P   P    P G  TSPPV P +   S  SP
Sbjct: 1610 PKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSP 1654



 Score = 89.7 bits (221), Expect = 2e-17
 Identities = 140/559 (25%), Positives = 201/559 (35%), Gaps = 81/559 (14%)

Query: 1066 PQHLQPSSSSGLGTSPSSSPRTSPCQS-PTISEGPVPSLPIRPSRAPSRTPGPPSAQSSP 1124
            P  + P S  G  T P+++P +    + P+  EGP P     P+  PS   GP     SP
Sbjct: 1335 PPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTP-----PAATPSHKGGPAMTPPSP 1389

Query: 1125 IDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRP--APPQR----PP---PPSGARSPA 1175
                PA P P+ DP  P      P   P  P TR   A P +    PP   P S  ++PA
Sbjct: 1390 -KRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPA 1448

Query: 1176 PTRKEFGGIGAPPSPGVARREMEAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAGYSTARP 1235
             +  + GG   P S G        P SP          +  SP+   A P P G     P
Sbjct: 1449 TSAPK-GGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMG----AP 1503

Query: 1236 TIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKP-QAAFPPQSSLPP 1294
            T+P  A + S+P+      + R  P + + T  + K     P  L P +A  PP  ++P 
Sbjct: 1504 TLP--AVIPSSPKEVPATPSSRRDPIAPTATLLSKK----TPATLAPKEALIPPAMTVPS 1557

Query: 1295 PAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQVKTNGISDGK 1354
            P    + P +P     P +       +PP   P +      P E    P V +   S  +
Sbjct: 1558 PK---KTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSP--SPKE 1612

Query: 1355 RESPLKIDPFEDLSFNLLAVSKAQLSVQTSPVPTPDPKRLIQLPSATQSNVLSSVSCMP- 1413
              +P  + P    S      + A     TSP  T  P  L   P++  S      + +P 
Sbjct: 1613 APTPPAVTP---PSPEKGPATPAPKGTPTSPPVT--PSSLKDSPTSPASVTCKMGATVPQ 1667

Query: 1414 TMPPIPARS--QSQENMRSSP----NPFITGLTRTNPFSDRTAAPGNPFRAKSEESEATS 1467
                +PA+    + + +  +P     P IT  TR  P + +++A   P            
Sbjct: 1668 ASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNG-- 1725

Query: 1468 WFSKEEPVTISPFPSLQPLGHNKSRASSSLDGFKDSFDLQGQSTLKISNPKGWVTFEEEE 1527
              SK    T++P P L P+  + S+ +   D              K S P     FE+  
Sbjct: 1726 --SKGPLSTVAPAP-LLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEK-- 1780

Query: 1528 DFGVKGKSKSACSDLLGNQPSSFSGSNLTLNDDWNKGTNVSFCVLPSRRPPPPPVPLLPP 1587
               V  K +SA      + P S                      LP     P PVP LPP
Sbjct: 1781 ---VLPKPESASVSAAPSPPVS----------------------LPL---APSPVPTLPP 1812

Query: 1588 GTS-PPVDPFTTLASKASP 1605
                 P  P   L S + P
Sbjct: 1813 KQQFLPSSPGLVLESPSKP 1831



 Score = 89.4 bits (220), Expect = 3e-17
 Identities = 98/392 (25%), Positives = 137/392 (34%), Gaps = 44/392 (11%)

Query: 1073 SSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQPATP 1132
            S  G  T P+++P +      T S    P+ P     +P   P  PS + +P       P
Sbjct: 935  SPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPP 994

Query: 1133 LPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRKEFGGIGAPPSPGV 1192
             P+  PA P  PK  P P  V PP+    P   P P GA +P            PPSP  
Sbjct: 995  SPKGGPATP-SPKGAPTPPAVTPPSPKGSPAATPFPKGASTPP--------AATPPSPKG 1045

Query: 1193 ARREMEAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAGYSTARPTIPPR-AGVISAPQSHA 1251
            +      PK   TT    +    PSP+ G A P   G  T     PP   G  + P    
Sbjct: 1046 SPAATPLPKGAPTTPAATL----PSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKG 1101

Query: 1252 RASAGRLTPESQS--------KTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQEPL 1303
                   TP S          K + T+  +T  P P    A  PP+ +   PA     P 
Sbjct: 1102 APMPPAATPPSPKGGLATPPHKGAPTTPAAT-PPSPKGGLATPPPKGAPTTPAATPPSPK 1160

Query: 1304 VPVAAPMPQSGPQPNLETPPQPPP--RSRSSHSLPSEASSQPQVKTNGIS----DGKRES 1357
              +A P P+  P     TPP P     + S    P+  ++ P     G++     G   +
Sbjct: 1161 GGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTT 1220

Query: 1358 PLKIDPFEDLSFNLLAVSKAQLS-VQTSPVP-----TPDPKRLIQLPSATQSNVLSSVSC 1411
            P    P         +   A  +   T P P     TP PK     P+AT  ++   ++ 
Sbjct: 1221 PAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLAT 1280

Query: 1412 MP---------TMPPIPARSQSQENMRSSPNP 1434
             P           PP P    +    + +P P
Sbjct: 1281 PPHKGAPNPAVVTPPSPKGGPATSPPKGAPTP 1312



 Score = 86.7 bits (213), Expect = 2e-16
 Identities = 113/443 (25%), Positives = 162/443 (36%), Gaps = 64/443 (14%)

Query: 1066 PQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPI 1125
            P   +P +   + TS  SSP+ +P     +     P+LP     +P   P  PS++  PI
Sbjct: 1473 PSPKEPPAPKQVATS--SSPKKAPATPAPMG---APTLPAVIPSSPKEVPATPSSRRDPI 1527

Query: 1126 DAQPATPLPQKDPAQPLEPKR---------PPPPRPVAPPTRPAPPQRPPPPSGARSPAP 1176
             A  AT L +K PA  L PK          P P +  A PT    P  P     +  PA 
Sbjct: 1528 -APTATLLSKKTPAT-LAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAV 1585

Query: 1177 TRKEFGGIGAP-----PSPGVARREMEAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAGYS 1231
            T   + G  +P     P    +    EAP  P  T         PSP+ G A P P G  
Sbjct: 1586 TPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVT--------PPSPEKGPATPAPKGTP 1637

Query: 1232 TARPTIPPRAGVISAPQSHARASA--GRLTPESQSKTSETSKGSTFLPEPL-KPQAAFPP 1288
            T+ P  P  + +  +P S A  +   G   P++ SK     KG T L E L  P     P
Sbjct: 1638 TSPPVTP--SSLKDSPTSPASVTCKMGATVPQA-SKGLPAKKGPTALKEVLVAPAPESTP 1694

Query: 1289 QSSLPP---PAQRLQEPLVPVAAPMPQS-----GPQPNLETPPQPPPRSRSSHSLPSEAS 1340
              + P    P  +      P   P P +     GP   +   P  P +  SS +   + +
Sbjct: 1695 IITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDA 1754

Query: 1341 SQPQVKTNGISDGKRESPLKIDPFEDL-------SFNLLAVSKAQLSVQTSPVPTPDPKR 1393
            S          + K  +PL    FE +       S +        L +  SPVPT  PK+
Sbjct: 1755 SHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQ 1814

Query: 1394 LIQLPSATQSNVLSSVS----------CMPTMPPIPARS--QSQENMRSSPNPFITGLTR 1441
              Q   ++   VL S S           +P +PP P       Q  + + P P   G+  
Sbjct: 1815 --QFLPSSPGLVLESPSKPLAPADEDELLPLIPPEPISGGVPFQSVLVNMPTPKSAGIPV 1872

Query: 1442 TNPFSDRTAAPGNPFRAKSEESE 1464
              P + +     N       +S+
Sbjct: 1873 PTPSAKQPVTKNNKGSGTESDSD 1895



 Score = 85.9 bits (211), Expect = 3e-16
 Identities = 100/413 (24%), Positives = 138/413 (33%), Gaps = 57/413 (13%)

Query: 1066 PQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLP---------------IRPSRA 1110
            P  + P S  G+   P  +P  S    P   EGP    P                R + A
Sbjct: 867  PSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPA 926

Query: 1111 PSRTPGPPSAQSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSG 1170
            P   P  PS + +P       P P+  PA P  PK  P P    PP+    P  P P   
Sbjct: 927  PKGIPASPSPKGAPTPPAATPPSPKGGPATP-SPKWAPTPPAATPPSPKGGPATPSPKGA 985

Query: 1171 ARSPAPTRKEFGGIGAPPSP-GVARREMEAPKSP-GTTRKDNIGRSQPSPQAGLAGPGPA 1228
               PA T     G  A PSP G        P SP G+       +   +P A    P P 
Sbjct: 986  PTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAA-TPPSPK 1044

Query: 1229 GYSTA------RPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPL-- 1280
            G   A       PT P  A  + +P+      + +  P   + T  + KG    P P   
Sbjct: 1045 GSPAATPLPKGAPTTP--AATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGA 1102

Query: 1281 -KPQAAFPPQS----SLPP-------PAQRLQEPLVPVAAPMPQSGPQPNLETPPQ---- 1324
              P AA PP      + PP       PA     P   +A P P+  P     TPP     
Sbjct: 1103 PMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGG 1162

Query: 1325 ---PPPRSRSSHSLPSEASSQPQVKTNGISDGKRESPLKIDPFEDLSFNLLAVSKAQLSV 1381
               PPP+   +    + A++ P  K    +   + +P             LA    + + 
Sbjct: 1163 LATPPPKGAPT----TPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAP 1218

Query: 1382 QTSPVPTPDPKRLIQLPSATQSNVLSSVSCMPTMPPIPARSQSQENMRSSPNP 1434
             T     P PK  +  PS   +    + +     PP P    +    + +P P
Sbjct: 1219 TTPAATPPSPKGGLATPSPKGAPTTPAAT-----PPSPKGGPATPPPKGAPTP 1266



 Score = 79.0 bits (193), Expect = 4e-14
 Identities = 95/364 (26%), Positives = 126/364 (34%), Gaps = 61/364 (16%)

Query: 1066 PQHLQPSSSSGLGTSPS-----SSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSA 1120
            PQ  +P +  G     +     SSP  SP ++  + E  +     + S A + +P PPS 
Sbjct: 803  PQTKRPPTKKGSAGPDTPIGNLSSP-VSPVEASFLPENSLSFQGSKDSPATTHSPTPPSP 861

Query: 1121 QSSPIDAQPATPLPQKDPAQPLEPKRPPPPR------PVAPPTRPAPPQRPPPPSGARSP 1174
            + +P  +   TPL  K    P  PK  P P       P   P  PAP Q P     + SP
Sbjct: 862  KGAPTPSA-VTPLSPKGVTLP--PKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSP 918

Query: 1175 APTRKEFGGIGAPPSPGVARREMEAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAGYSTAR 1234
               R      G P SP        AP  P  T         PSP+ G A P P    T  
Sbjct: 919  KKARATPAPKGIPASPS----PKGAPTPPAAT--------PPSPKGGPATPSPKWAPTPP 966

Query: 1235 PTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPP 1294
               PP      +P+      + +  P   + T  + KG    P P    A  PP  + P 
Sbjct: 967  AATPP------SPKGGPATPSPKGAPTPPAATPPSPKGGPATPSP--KGAPTPPAVTPPS 1018

Query: 1295 PAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQVKTNGISDGK 1354
            P         P A P P+    P   TPP  P  S ++  LP  A + P         G 
Sbjct: 1019 PKGS------PAATPFPKGASTPPAATPPS-PKGSPAATPLPKGAPTTPAATLPSPKGGP 1071

Query: 1355 RESPLKIDPFEDLSFNLLAVSKAQLSVQTSPVP-----TPDPKRLIQLPSATQSNVLSSV 1409
                LK  P    +              T P P     TP PK     P+AT  +    +
Sbjct: 1072 ATPSLKGAPTPPAA--------------TPPSPKGGPATPSPKGAPMPPAATPPSPKGGL 1117

Query: 1410 SCMP 1413
            +  P
Sbjct: 1118 ATPP 1121



 Score = 61.6 bits (148), Expect = 6e-09
 Identities = 80/362 (22%), Positives = 122/362 (33%), Gaps = 66/362 (18%)

Query: 1084 SPRTSPCQSPTISEGPVPSLPIRPSRAPSRTP----GPPSAQSSPIDAQPATPLPQKDPA 1139
            SP+ +P   PT  E P        S  P+ TP    G PS +   I     +P P++ P 
Sbjct: 1557 SPKKTPA-IPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPT 1615

Query: 1140 QPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGAR----SPAPTRKEFG--------GIGAP 1187
             P      P   P  P  +  P   P  PS  +    SPA    + G        G+ A 
Sbjct: 1616 PPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAK 1675

Query: 1188 PSPGVARREMEAPKSPGT------TRKDNIGRSQ--------PSPQAGLAGPGPAGYSTA 1233
              P   +  + AP    T      TRK    +          P P A     GP      
Sbjct: 1676 KGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAP 1735

Query: 1234 RPTIPPRA----------------GVISAPQSHAR-----ASAGRLTPESQSKT-SETSK 1271
             P +P +                 G ++ P+S A      A+  ++ P+ +S + S    
Sbjct: 1736 APLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPS 1795

Query: 1272 GSTFLPEPLKPQAAFPPQSSLPPPAQRL-------------QEPLVPVAAPMPQSGPQPN 1318
                LP    P    PP+    P +  L             ++ L+P+  P P SG  P 
Sbjct: 1796 PPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEPISGGVPF 1855

Query: 1319 LETPPQPPPRSRSSHSLPSEASSQPQVKTNGISDGKRESPLKIDPFEDLSFNLLAVSKAQ 1378
                   P    +   +P+ ++ QP  K N  S  + +S   +   E+         +AQ
Sbjct: 1856 QSVLVNMPTPKSAGIPVPTPSAKQPVTKNNKGSGTESDSDESVPELEEQDSTQATTQQAQ 1915

Query: 1379 LS 1380
            L+
Sbjct: 1916 LA 1917



 Score = 55.1 bits (131), Expect = 5e-07
 Identities = 126/511 (24%), Positives = 185/511 (36%), Gaps = 82/511 (16%)

Query: 1077 LGTSPSSSPRTSPCQSPTISEGPV----PSLPIRPSRAPSRTPGPPSAQSSPIDAQPATP 1132
            +  +P+++   + C SP +S GP+    P+ P     AP     P +  ++ +    + P
Sbjct: 449  IAAAPTTTFEVATCVSPPMSSGPISNIEPTSPAALVMAPVAPKEPSTQVATTLRIPVSPP 508

Query: 1133 LPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRKEFGGIGAPPSPGV 1192
            LP      P + K  P    V  PT+      P    G    AP      G+     P V
Sbjct: 509  LP-----DPEDLKNLPSSVLVKFPTQKDLQTVPASLEG----APFSPAQAGLTTKKDPTV 559

Query: 1193 ARREMEAPKSPGTTRKDNIGRSQP-SPQAGLA-----GPGPAGYSTARPTIP----PRAG 1242
                  APK+  + +  +     P SP+A LA      P P G   +  T P      A 
Sbjct: 560  LPLVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGKPASSMTSPLGVNSSAS 619

Query: 1243 VISAPQSHARASAGRL------TPESQSKTSETSKGSTFLPEPLKPQAAFPPQS------ 1290
            VI         SAG L      TP   +   E++  +   P   K  + +   +      
Sbjct: 620  VIKTDSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEG 679

Query: 1291 --SLPPPAQRLQE------PLVPVA------APMPQS--GPQPNLETPPQPPPRSRSSHS 1334
              SL P    ++E      PLVP A      AP PQ+   P   L   P+  P+S  S S
Sbjct: 680  TVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPE-IPKSVPSPS 738

Query: 1335 LPSEASSQPQVKTNGISDGKRESPL----KIDPFEDLSFNLLAVSKAQLS-VQTSPVP-- 1387
            LP   +     K +GIS     +P+    K  P ED   +  A SK  L+ +  SP P  
Sbjct: 739  LPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLG 798

Query: 1388 --------TPDPKRLIQLPSATQSNVLSSVSCMPTMPPIPARSQSQENMRSSPNPFITGL 1439
                     P  K+    P     N+ S VS +     +P  S S +  + SP       
Sbjct: 799  VSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEA-SFLPENSLSFQGSKDSP-ATTHSP 856

Query: 1440 TRTNPFSDRTAAPGNPFRAKS-----EESEATSW----FSKEEPVTISPFP----SLQPL 1486
            T  +P    T +   P   K      +E+   S     F KE P T +P      S+   
Sbjct: 857  TPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSS 916

Query: 1487 GHNKSRASSSLDGFKDSFDLQGQSTLKISNP 1517
               K+RA+ +  G   S   +G  T   + P
Sbjct: 917  SPKKARATPAPKGIPASPSPKGAPTPPAATP 947



 Score = 53.9 bits (128), Expect = 1e-06
 Identities = 93/392 (23%), Positives = 131/392 (33%), Gaps = 82/392 (20%)

Query: 1117 PPSAQSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAP 1176
            P + Q  P        LP             P P  + PP  PAP Q P   +   SP P
Sbjct: 10   PATEQELPQPQAETAVLPMSSALSVTAALGQPGPT-LPPPCSPAPQQCPLSAANQASPFP 68

Query: 1177 TRKEFGGIGAPPSPGVARREMEAP---KSPGTTRKDNIGRSQPSPQAGLAGP--GPAGYS 1231
            +          PS  +A   +E P    S GT          P+    L GP   PA  +
Sbjct: 69   S----------PST-IASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALA 117

Query: 1232 TARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSS 1291
             A P I P   +   P S A  +   L P S  K+S                 AFPP   
Sbjct: 118  LASPMIAPT--LKGTPSSSAPLALVALAPHSVQKSS-----------------AFPPNLL 158

Query: 1292 LPPPAQRLQE--PLVPVAAPMPQSGPQPNL-ETPPQPPPRSRSSHSLPSEASSQPQVKTN 1348
              PP+  + E   ++ ++AP+  S P+ NL + P +  P  + + S P   S+ P     
Sbjct: 159  TSPPSVAVAESGSVITLSAPIAPSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPY---- 214

Query: 1349 GISDGKRESPLKIDPFEDLSFNLLAVSKAQLSVQTSPVPTPDPKRLIQLPSATQSNVLSS 1408
                                  +  ++  Q  V + P  TP     I  P   +   +SS
Sbjct: 215  --------------------HCVTPMASIQSGVASLPQTTPTTTLAIASPQ-VKDTTISS 253

Query: 1409 VSCMPTMPPI-----PARSQSQENMRSSPNPFITGLTRTNPFSDRTAAPGNPFRAKSEES 1463
            V   P  P       P    +  ++ +   P +T        S +TA P  P        
Sbjct: 254  VLISPQNPGSLSLKGPVSPPAALSLSTQSLPVVTS-------SQKTAGPNTP------PD 300

Query: 1464 EATSWFSKEEPVTISPFPSLQPLGHNKSRASS 1495
               S  S   P+  S F S+Q LG     A S
Sbjct: 301  FPISLGSHLAPLHQSSFGSVQLLGQTGPSALS 332



 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 90/400 (22%), Positives = 137/400 (34%), Gaps = 61/400 (15%)

Query: 1050 MEGDVDDYSAEVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSR 1109
            M G+  +     E+ LPQ   P + + +       P +S          P P+LP     
Sbjct: 1    MPGEATETVPATEQELPQ---PQAETAV------LPMSSALSVTAALGQPGPTLP----- 46

Query: 1110 APSRTPGPPSAQSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAP-------- 1161
             P  +P P     S  +     P P    + PLE   P      A P   AP        
Sbjct: 47   -PPCSPAPQQCPLSAANQASPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPN 105

Query: 1162 ---PQRPPPPSGARSP--APTRKEFGGIGAPPSPGVARREMEAPKSPGTTRKDNIGRSQP 1216
               P   P      SP  APT K     G P S         AP +       ++ +S  
Sbjct: 106  LIGPPISPAALALASPMIAPTLK-----GTPSS--------SAPLALVALAPHSVQKSSA 152

Query: 1217 SPQAGLAGPGPAGYSTARPTIPPRAGVI-SAPQSHARASAGRLTPESQSKTSETSKGSTF 1275
             P   L  P     + +   I   A +  S P+++       + P  +   S     ST 
Sbjct: 153  FPPNLLTSPPSVAVAESGSVITLSAPIAPSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTV 212

Query: 1276 LPEPLKPQAAF----------PPQSSLPPPAQRLQEPLVPVAAPMPQSGPQPNLETPPQP 1325
                + P A+            P ++L   + ++++  +      PQ+    +L+ P  P
Sbjct: 213  PYHCVTPMASIQSGVASLPQTTPTTTLAIASPQVKDTTISSVLISPQNPGSLSLKGPVSP 272

Query: 1326 PPR-SRSSHSLPSEASSQPQVKTNGISDGKRESPLKIDPFEDLSFNLLAVSKAQLSVQTS 1384
            P   S S+ SLP   SSQ     N   D        + P    SF        QL  QT 
Sbjct: 273  PAALSLSTQSLPVVTSSQKTAGPNTPPDFPISLGSHLAPLHQSSF-----GSVQLLGQTG 327

Query: 1385 PVPTPDPKRLIQLPSATQSNVLSSV-SCMPTMPPIPARSQ 1423
            P    DP   ++  S   S+  +S  S    +PP+P+R++
Sbjct: 328  PSALSDP--TVKTISVDHSSTGASYPSQRSVIPPLPSRNE 365



 Score = 43.5 bits (101), Expect = 0.002
 Identities = 121/585 (20%), Positives = 194/585 (33%), Gaps = 114/585 (19%)

Query: 1018 EEMSLEKISIALPSSTSSTLLGEDAEVAADFDMEGDVDDYSA--EVEELLPQHLQPSSSS 1075
            ++  L   + A P  + ST+     EV       G         E    LP  + P    
Sbjct: 54   QQCPLSAANQASPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPP--- 110

Query: 1076 GLGTSPSSSPRTSPCQSPTISEGPVPSLPIR-----PSRAPSRTPGPPSAQSSPID---A 1127
                SP++    SP  +PT+   P  S P+      P      +  PP+  +SP     A
Sbjct: 111  ---ISPAALALASPMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVA 167

Query: 1128 QPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSP-----APTRKEFG 1182
            +  + +    P  P EPK       V     P P   P PP    +       P      
Sbjct: 168  ESGSVITLSAPIAPSEPKTNL--NKVPSEVVPNPKGTPSPPCIVSTVPYHCVTPMASIQS 225

Query: 1183 GIGA-PPSPGVARREMEAPKSPGTTRKDNIGRSQPSPQAGLAGP--GPAGYSTARPTIP- 1238
            G+ + P +       + +P+   TT    +   Q      L GP   PA  S +  ++P 
Sbjct: 226  GVASLPQTTPTTTLAIASPQVKDTTISSVLISPQNPGSLSLKGPVSPPAALSLSTQSLPV 285

Query: 1239 ----PRAGVISAPQSHARASAGRLTPESQSKTSETS----KGSTFLPEPL---------K 1281
                 +    + P     +    L P  QS           G + L +P           
Sbjct: 286  VTSSQKTAGPNTPPDFPISLGSHLAPLHQSSFGSVQLLGQTGPSALSDPTVKTISVDHSS 345

Query: 1282 PQAAFPPQSSLPPPAQRLQEPL------VPVAAPMPQSGPQ--PNLETPPQPPPRSRSSH 1333
              A++P Q S+ PP     E +       PV AP    GP    ++   P       +S 
Sbjct: 346  TGASYPSQRSVIPPLPSRNEVVPATVAAFPVVAPSVDKGPSTISSITCSPSGSLNVATSF 405

Query: 1334 SLP-------------------------SEASSQPQVKTNG----------------ISD 1352
            SL                          S   + P V TN                 +S 
Sbjct: 406  SLSPTTSLILKSSPNATYHYPLVAQMPVSSVGTTPLVVTNPCTIAAAPTTTFEVATCVSP 465

Query: 1353 GKRESPL-KIDPFEDLSFNLLAVSKAQLSVQTS-----PV--PTPDPKRLIQLPSA---- 1400
                 P+  I+P    +  +  V+  + S Q +     PV  P PDP+ L  LPS+    
Sbjct: 466  PMSSGPISNIEPTSPAALVMAPVAPKEPSTQVATTLRIPVSPPLPDPEDLKNLPSSVLVK 525

Query: 1401 --TQSNVLSSVSCMPTMPPIPARSQSQENMRSSPNPFITGLTRTNP-FSDRTAAPGNPFR 1457
              TQ ++ +  + +   P  PA++        +  P +    + +P F   +++P  P  
Sbjct: 526  FPTQKDLQTVPASLEGAPFSPAQAGLTTKKDPTVLPLVQAAPKNSPSFQSTSSSPEIPLS 585

Query: 1458 AKSEESEATSWFSKEEPVTI-SPFPSL-QPLGHNKSRASSSLDGF 1500
             ++  ++     S  EP+ I  P  S+  PLG N S +    D +
Sbjct: 586  PEATLAKK----SLGEPLPIGKPASSMTSPLGVNSSASVIKTDSY 626


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
          Length = 1124

 Score = 91.7 bits (226), Expect = 5e-18
 Identities = 147/538 (27%), Positives = 195/538 (36%), Gaps = 122/538 (22%)

Query: 1064 LLPQHLQPSSSSGLGTSPSSSPR--TSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQ 1121
            L P  LQ +S+      P ++P   T PC +P   + P   L   P   PS    PP  Q
Sbjct: 541  LAPPPLQTASA------PLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPP-PQ 593

Query: 1122 SSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPP-QRPPPPSGARSPAPTRKE 1180
            + P  A P  PL Q  P+ PL P   PPP+  APP    PP Q PP P  +   +P    
Sbjct: 594  APPALASP--PL-QGLPSPPLSPLATPPPQ--APPXLALPPLQAPPSPPASPPLSPL--- 645

Query: 1181 FGGIGAPPSP----GVARREMEAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAGYSTARPT 1236
                 A PSP     +A   ++AP SP            PSP        PA    +   
Sbjct: 646  -----ATPSPQAPNALAVHLLQAPFSP-----------PPSPPVQAPFSPPASPPVSPSA 689

Query: 1237 IPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPA 1296
             PP      AP S   A+     P S   +   S  +T  P+   P AA P Q    PPA
Sbjct: 690  TPPS----QAPPS--LAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPA 743

Query: 1297 QRLQEPLVPVAAPMPQSGP---QPNLETPPQPPPRSRSSHSLPSEASSQPQVKTNGISDG 1353
                 P+ P A P P+  P    P L+ PP PP       SLP    ++P  +       
Sbjct: 744  ---SPPMSPSATPPPRVPPLLAAPPLQVPPSPPA------SLPMSPLAKPPPQA---PPA 791

Query: 1354 KRESPLKIDPFEDLSFNLLAVSKAQLSVQTSPVPTPDPKRLIQLPSATQSNVLSSVSCMP 1413
                PL+  P    SF   A      S+  SP+ TP P    Q P    + +L       
Sbjct: 792  LATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPP----QAPPVLAAPLLQ------ 841

Query: 1414 TMPPIPARSQSQENMRSSPNPFITGLTRTNPFSDRTAAPGNPFRAKSEESEATSWFSKEE 1473
             +PP P  S + +  R  P P     + + P      APG P                  
Sbjct: 842  -VPPSPPASPTLQAPRRPPTPG-PDTSVSGPRLTLALAPGPP------------------ 881

Query: 1474 PVTISPFPSLQPLGHNKSRASSSLDGFKDSFDLQGQSTLKISNPKGWVTFEEEEDFGVKG 1533
                 P PS  P        SS+L G     DL G S+   S P+    ++   + G   
Sbjct: 882  -----PPPSRSP--------SSTLSG----PDLAGHSSSATSTPEELRGYDSGPEGGA-A 923

Query: 1534 KSKSACSDLLGNQPSSFSGSNLTLNDDWNKGTNVSFCVLPSRRPPPPPVPLLPPGTSP 1591
             S    ++L    P++           W++G       L  R  P  P+P  PP T P
Sbjct: 924  ASPPPDAELAACHPAA-----------WSRGPAPP---LAFRGAPGAPLP-WPPATGP 966



 Score = 89.0 bits (219), Expect = 3e-17
 Identities = 110/416 (26%), Positives = 160/416 (38%), Gaps = 71/416 (17%)

Query: 1069 LQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVP-SLPIRPSRAPSRTPGPPSAQSSP--- 1124
            L P SSS L T   S  +  P   P  +  P+P +LP  P  A      PPS  + P   
Sbjct: 296  LGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQ 355

Query: 1125 -IDAQPATPLPQKDPAQPLEPKRPPPPRPVAPP-------TRPAPPQRPPPPSGARSPAP 1176
             + + PATP  Q  P+    P + PP     PP       T P+  Q PP P    S   
Sbjct: 356  TLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPS-LQAPPSPLALSSLQA 414

Query: 1177 TRKEFGGIGAPP----------SPGVARREMEAPKSPGTTRKDNIGRSQPSPQAGLAGP- 1225
            T      +G+P           SP   +  + +P  P +T  D+     P  QA L+ P 
Sbjct: 415  TT----SLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDS-----PPLQAPLSLPA 465

Query: 1226 GPAGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAA 1285
             P   ++  P + P +  ++     A +S    +P++          S+ +  PL+ Q++
Sbjct: 466  SPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPL--------SSLIMPPLETQSS 517

Query: 1286 FPPQSSLPPPAQRLQEPL--VPVAAPMP---QSGP--QPNLETPPQPPPRSRSSHSLPSE 1338
              P S   PPA     PL  +P  AP P    S P   P+LETPP P P    +   PS 
Sbjct: 518  LAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAP--PSP 575

Query: 1339 ASSQPQVKTNGISDGKRESP--LKIDPFEDLSFNLLAVSKAQLSVQTSPVPTPDPKRLIQ 1396
             ++ P    + I+    ++P  L   P + L            S   SP+ TP P+    
Sbjct: 576  LTTPPPETPSSIATPPPQAPPALASPPLQGLP-----------SPPLSPLATPPPQ---- 620

Query: 1397 LPSATQSNVLSSVSCMPTMPPIPARSQSQENMRSSPNPFITGLTRTNPFSDRTAAP 1452
               A     L  +   P+ P  P  S        +PN     L +  PFS   + P
Sbjct: 621  ---APPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQA-PFSPPPSPP 672



 Score = 81.3 bits (199), Expect = 7e-15
 Identities = 154/579 (26%), Positives = 198/579 (34%), Gaps = 121/579 (20%)

Query: 1066 PQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSP- 1124
            P+    S+S    T PS + R  P     +      SL    +   S     PSA+ +P 
Sbjct: 205  PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPR 264

Query: 1125 IDAQPATPLPQKDPAQPLEPKRPPPPR-------------PVAPPTRPAPPQRP-PPPSG 1170
              A P+ P P+    Q L P +  PPR             P+A P+      RP PPP  
Sbjct: 265  APAHPSQPKPK--GLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDN 322

Query: 1171 ARSPAPTRKEFGGIGAPPSPGVARREMEAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAGY 1230
            A +P P          PPSP +A     AP SP         ++ PSP A      P   
Sbjct: 323  AATPLPAT-------LPPSPPLATPLPLAPPSPSAPPS---LQTLPSPPATPPSQAPPSM 372

Query: 1231 STARPTIPPRAGVISAPQ-SHARASAGRLTPES----QSKTSETSKGSTFLP-------- 1277
            +T     PP    I   Q  H+  S     P S     S  + TS GS  L         
Sbjct: 373  TTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTM 432

Query: 1278 EPLKPQAAFPPQS---SLPPPAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHS 1334
             P + QA+    S   S PP +  LQ PL   A+P  Q+   P + +P   P       +
Sbjct: 433  SPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAV-SPLSSPLTIHPLQA 491

Query: 1335 LPSEASSQPQVKTNGISDGKRESPLKIDPFEDLSFNLLAVSKAQLSVQTSPVPTPDPKRL 1394
            L S AS  PQ            S L + P E  S      S A  S+QT P     P  L
Sbjct: 492  LSSLASHSPQAPL---------SSLIMPPLETQS------SLAPPSLQTPPASLTTPP-L 535

Query: 1395 IQLPSATQSNVLSSVSCMPT----MPPIPARSQSQENMRSSPNPFITGLTRTNPFSDRTA 1450
              LPS     + ++ + + T     PP PA       +++ P+P  T    T P S  T 
Sbjct: 536  ENLPSLAPPPLQTASAPLTTPHLETPPCPAPCP----LQAPPSPLTTPPPET-PSSIATP 590

Query: 1451 APGNPFRAKSEESEATSWFSKEEPVTISPFPSLQPLGHNKSRASSSLDGFKDSFDLQGQS 1510
             P  P    S             P+   P P L PL     +A   L        LQ   
Sbjct: 591  PPQAPPALAS------------PPLQGLPSPPLSPLATPPPQAPPXL----ALPPLQAPP 634

Query: 1511 TLKISNPKGWVTFEEEEDFGVKGKSKSACSDLLGNQPSSFSGSNLTLNDDWNKGTNVSFC 1570
            +   S P                      S L    P +                 V   
Sbjct: 635  SPPASPP---------------------LSPLATPSPQA------------PNALAVHLL 661

Query: 1571 VLPSRRPPPPPV--PLLPPGTSPPVDPFTTLASKASPTL 1607
              P   PP PPV  P  PP  SPPV P  T  S+A P+L
Sbjct: 662  QAPFSPPPSPPVQAPFSPP-ASPPVSPSATPPSQAPPSL 699



 Score = 80.1 bits (196), Expect = 2e-14
 Identities = 121/474 (25%), Positives = 176/474 (37%), Gaps = 69/474 (14%)

Query: 1076 GLGTSPSSSPRTSPCQSP-TISEGPVPSLPI--RPSRAPSRTPGPPSAQSSPIDAQPAT- 1131
            G  T P S+PR  P +S  T S  P    P   R  RAP      P   SSP  A   T 
Sbjct: 66   GGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTR 125

Query: 1132 --PLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRKEFGGIGAPPS 1189
              PL QK         R      VA       P+R    +GAR     R   G     PS
Sbjct: 126  PGPLGQKG-------LRISAEETVARGKATEAPKRSALSAGAR-----RDTSGPTPGTPS 173

Query: 1190 PGVARREMEAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAG-YSTARPT-----IPPRAGV 1243
            P +ARR   A    G  R     R +P  +        A  +ST  P+      P   G 
Sbjct: 174  PAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGG 233

Query: 1244 ISAPQSHARASAGRLTP-ESQSKTSETSKGSTFLP-EPLKP-----QAAFPPQSSLPPPA 1296
            +  P S + +S+   TP  S +++  +++G+   P  P +P     QA  PPQ  + PP 
Sbjct: 234  LQRPASRSLSSSA--TPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQ--VTPPR 289

Query: 1297 QRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQVKTNGISDGKRE 1356
            +     L P+++  P + P P+       PP   ++  LP+     P + T         
Sbjct: 290  KDAAPALGPLSS-SPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLAT--------- 339

Query: 1357 SPLKIDPFEDLSFNLLAVSKAQLSVQTSPVPTPDPKRLIQLPSATQSNVLSSVSCMPTMP 1416
             PL + P             A  S+QT P P   P    Q P +  +  + +   + T+P
Sbjct: 340  -PLPLAP---------PSPSAPPSLQTLPSPPATPPS--QAPPSMTTPPMQAPPSLQTIP 387

Query: 1417 PIPA-RSQSQENMRSSPNPF-ITGLTRTNPFSDRTAAPGNPFRAKSEESEATSWFSKEEP 1474
            PI    S +  ++++ P+P  ++ L  T      T    + F   S      S  S   P
Sbjct: 388  PIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRP 447

Query: 1475 VTISP----------FPSLQPLGHNKSRASSSLDGFKDSFDLQGQSTLKISNPK 1518
             +  P           P+  PL  + S A S L        LQ  S+L   +P+
Sbjct: 448  ASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQ 501



 Score = 74.7 bits (182), Expect = 7e-13
 Identities = 90/305 (29%), Positives = 113/305 (37%), Gaps = 73/305 (23%)

Query: 1058 SAEVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGP 1117
            S +    L  HL  +  S   + P  +P  SP  SP +S    P     PS A      P
Sbjct: 649  SPQAPNALAVHLLQAPFSPPPSPPVQAP-FSPPASPPVSPSATPPSQAPPSLAAPPLQVP 707

Query: 1118 PSAQSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPA--PPQRPPPPSGARSPA 1175
            PS  +SP  +  ATP PQ  P     P + PP  P +PP  P+  PP R PP   A    
Sbjct: 708  PSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPP-- 765

Query: 1176 PTRKEFGGIGAPPSPGVARREMEAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAGYSTARP 1235
                    +  PPSP  +      P SP          ++P PQA      P   +T   
Sbjct: 766  --------LQVPPSPPAS-----LPMSP---------LAKPPPQA------PPALAT--- 794

Query: 1236 TIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPP 1295
              PP   + S P     AS     P S S +            P+ P A  PPQ+     
Sbjct: 795  --PPLQALPSPP-----ASFPGQAPFSPSASL-----------PMSPLATPPPQAPPVLA 836

Query: 1296 AQRLQEPLVPVAAP---MPQSGPQPNLET------------PPQPPPRSRSSHSLPSEAS 1340
            A  LQ P  P A+P    P+  P P  +T            P  PPP SRS    PS   
Sbjct: 837  APLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRS----PSSTL 892

Query: 1341 SQPQV 1345
            S P +
Sbjct: 893  SGPDL 897



 Score = 55.8 bits (133), Expect = 3e-07
 Identities = 87/352 (24%), Positives = 130/352 (36%), Gaps = 55/352 (15%)

Query: 1142 LEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRKEFGGIG------APPSPGVARR 1195
            L P+ P  PRP  PP  PA   R    +GA    P  +  GGIG      + P  G  R 
Sbjct: 25   LTPRPPGSPRP-PPPVTPAA-LRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRS 82

Query: 1196 EMEAPKSPGTTRKDNIGRSQPSPQAGLAGPGPA-----GYSTARPTIPPRAGV-ISAPQS 1249
               + ++P  +R    GR + +P A    PGP         T RP    + G+ ISA ++
Sbjct: 83   AGTSSRNP-ASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEET 141

Query: 1250 HARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQEPLVPVAAP 1309
             AR  A       +S  S  ++  T  P P  P  A   +S        L  P  P A P
Sbjct: 142  VARGKA--TEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRP-APSARP 198

Query: 1310 MPQS-GPQPNLE-------TPPQPPPRSRSS--HSLPSEASSQPQVKTNGISDGKRESP- 1358
             P + GP+ ++        T P P  R R S    L   AS         +S   R  P 
Sbjct: 199  RPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPS 258

Query: 1359 ------LKIDPFEDLSFNLLAVSKAQLS------------VQTSPVPTPDPKRLIQLPSA 1400
                      P +     L A+   Q++            + +SP+ TP P      P  
Sbjct: 259  ARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVP 318

Query: 1401 TQSNVLSSV-SCMPTMPPI-------PARSQSQENMRSSPNPFITGLTRTNP 1444
               N  + + + +P  PP+       P    +  ++++ P+P  T  ++  P
Sbjct: 319  PPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPP 370


>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
          Length = 1012

 Score = 90.9 bits (224), Expect = 9e-18
 Identities = 104/355 (29%), Positives = 139/355 (39%), Gaps = 74/355 (20%)

Query: 1049 DMEGDVDDYSAEVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPS---LPI 1105
            D E D D  SA+ + L  Q     + +G+  +PSS+P  +P Q PT   GP PS   +P 
Sbjct: 166  DNESDSDS-SAQQQMLQAQPPALQAPTGVTPAPSSAPPGTP-QLPT--PGPTPSATAVPP 221

Query: 1106 RPSRAPSRTPGPPSAQSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRP------ 1159
            + S   S+ P  P A ++P+        P   P +P  P  PP P P  PP +P      
Sbjct: 222  QGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSP-HPPLQPLTGSAG 280

Query: 1160 ---APPQRPPPPSGARSPAPTRKEFGGI----------GAPP-----------SPGVA-- 1193
               AP    PP  G   P P   + G +          G PP           SP  A  
Sbjct: 281  QPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYP 340

Query: 1194 RREMEAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAGYSTARPTIPPRAGVISAPQSHARA 1253
               ++ P S    +     R QP P A LA P    +    PT P     + APQ+H   
Sbjct: 341  HTSLQLPASQSALQSQQPPREQPLPPAPLAMP----HIKPPPTTP--IPQLPAPQAHKH- 393

Query: 1254 SAGRLTPESQSKTSETSKGSTFLPEP-LKPQAAFP---PQSSLPPPAQRLQEPLVPVAAP 1309
                  P   S  S  S  +   P P LKP ++     P S+ PPP Q            
Sbjct: 394  ------PPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQL----------- 436

Query: 1310 MPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQVKTNGISDGKRESPLKIDPF 1364
            MPQS P P+  +P QPP  ++S +  P  AS  P     G+     + P    PF
Sbjct: 437  MPQSQPLPS--SPAQPPGLTQSQNLPPPPASHPP----TGLHQVAPQPPFAQHPF 485



 Score = 58.2 bits (139), Expect = 6e-08
 Identities = 99/441 (22%), Positives = 139/441 (31%), Gaps = 77/441 (17%)

Query: 1043 EVAADFDMEGDVDDYSAEVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPS 1102
            +VA+D +          + +E+   +  PS   G  +   S           I +    +
Sbjct: 99   KVASDTEEADRTSSKKTKTQEISRPN-SPSEGEGESSDSRSVNDEGSSDPKDIDQDNRST 157

Query: 1103 LPIRPSRAPSRTPGPPSAQSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPP 1162
             P  PS   + +    SAQ   + AQP        PA        P P   APP  P  P
Sbjct: 158  SPSIPSPQDNESDSDSSAQQQMLQAQP--------PALQAPTGVTPAPSS-APPGTPQLP 208

Query: 1163 QRPPPPSGARSPAPTRKEFGGIGAPPSPGVARREMEAPKSPGTTRKDNIGRSQPSPQAGL 1222
               P PS    P             P+   A  + +AP +P      +I ++        
Sbjct: 209  TPGPTPSATAVPPQ---------GSPTASQAPNQPQAPTAP--VPHTHIQQAPALHPQRP 257

Query: 1223 AGPGPAGYSTARPTIPPRAGVISAPQ--SHAR-------------ASAGRL-----TPES 1262
              P P  + +  P + P  G    P   SHA+               AG L      P+ 
Sbjct: 258  PSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQP 317

Query: 1263 QSKTSETSKGSTFLPEPLKPQAAFP--------PQSSLPPPAQRLQEPLVPVAAPMPQSG 1314
                 + S+G    P    P AA+P         QS+L       ++PL P    MP   
Sbjct: 318  FGLPPQASQGQA--PLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIK 375

Query: 1315 PQPNLETPPQPPPRSRSSHSLPSEASSQPQVKTNGISDGKRESPLKIDPFEDLSFNLLAV 1374
            P P    P  P P+   +H  P   S       N         P  + P   LS +    
Sbjct: 376  PPPTTPIPQLPAPQ---AHKHPPHLSGPSPFSMN----ANLPPPPALKPLSSLSTH-HPP 427

Query: 1375 SKAQLSVQTSPVPTPDPKRLIQLPSATQSNVLSSVSCMPTMPPIPARSQSQENMRSSPNP 1434
            S     +Q  P   P P    Q P  TQS           +PP PA        + +P P
Sbjct: 428  SAHPPPLQLMPQSQPLPSSPAQPPGLTQSQ---------NLPPPPASHPPTGLHQVAPQP 478

Query: 1435 FITGLTRTNPFSDRTAAPGNP 1455
                     PF+     PG P
Sbjct: 479  ---------PFAQHPFVPGGP 490



 Score = 41.6 bits (96), Expect = 0.006
 Identities = 48/149 (32%), Positives = 59/149 (39%), Gaps = 18/149 (12%)

Query: 1066 PQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRP-SRAPSRTPGPPSAQSSP 1124
            P  L+P SS      PS+ P   P Q    S+ P+PS P +P     S+   PP A   P
Sbjct: 412  PPALKPLSSLSTHHPPSAHP--PPLQLMPQSQ-PLPSSPAQPPGLTQSQNLPPPPASHPP 468

Query: 1125 IDAQPATPLPQKDPAQPLEPKRPPPPRPV---APPTRPAPP--QRPPPPSGARSPAPTRK 1179
                   P P      P  P  PPP  P    +  T PA P     PP SGA   A +  
Sbjct: 469  TGLHQVAPQPPF-AQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGA---AASGG 524

Query: 1180 EFGGIGAPPSPGVARRE-----MEAPKSP 1203
               G  + P P V  +E      E P+SP
Sbjct: 525  SIAGGSSCPLPTVQIKEEALDDAEEPESP 553



 Score = 39.3 bits (90), Expect = 0.031
 Identities = 47/155 (30%), Positives = 61/155 (39%), Gaps = 36/155 (23%)

Query: 1068 HLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVP-----SLPIRPSRAPSR---TPGPPS 1119
            H++P  ++ +   P+      P   P +S GP P     +LP  P+  P     T  PPS
Sbjct: 373  HIKPPPTTPIPQLPAPQAHKHP---PHLS-GPSPFSMNANLPPPPALKPLSSLSTHHPPS 428

Query: 1120 AQSSPIDAQPAT-PLPQKDPAQP---LEPKRPPPPRPVAPPT-----RPAPP--QRP--- 1165
            A   P+   P + PLP   PAQP    + +  PPP    PPT      P PP  Q P   
Sbjct: 429  AHPPPLQLMPQSQPLPSS-PAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVP 487

Query: 1166 -------PPPSGARSPAPTRKEFGGIGAPPSPGVA 1193
                   PP   + S  P     G    PP  G A
Sbjct: 488  GGPPPITPPTCPSTSTPPAGP--GTSAQPPCSGAA 520



 Score = 34.7 bits (78), Expect = 0.77
 Identities = 83/386 (21%), Positives = 138/386 (35%), Gaps = 76/386 (19%)

Query: 1245 SAPQSHARASAGRLTPESQSKTSETSKGSTFLP--EPLKPQAAFPPQSSLPPPAQRLQEP 1302
            ++P +    S+GR +P + S +S  SK  T     + +K +A+ P +S+     +R +E 
Sbjct: 45   TSPINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSN-----KRQREK 99

Query: 1303 LVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQVKTNGISDGK-------R 1355
               VA+   ++    + +T  Q   R  S      E+S    V   G SD K        
Sbjct: 100  ---VASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRS 156

Query: 1356 ESPLKIDPFEDLSFNLLAVSKAQLSVQ---------TSPVPTPDPKRLIQLPSATQSNVL 1406
             SP    P ++ S +  +  +  L  Q          +P P+  P    QLP  T     
Sbjct: 157  TSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLP--TPGPTP 214

Query: 1407 SSVSCMPTMPPIPARSQSQENMRSSPNPFITGLTRTNPFSDRTAAPGNPFRAKSEESEAT 1466
            S+ +  P   P  +++ +Q    ++P P       T+        P  P           
Sbjct: 215  SATAVPPQGSPTASQAPNQPQAPTAPVP------HTHIQQAPALHPQRPP---------- 258

Query: 1467 SWFSKEEPVTISPFPSLQPLGHNKSRASSSL--------DGFKDSFDLQGQSTLKISNPK 1518
               S   P   SP P LQPL  +  + S+           G      LQ    L+   P 
Sbjct: 259  ---SPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPP 315

Query: 1519 GWVTFEEEEDFGVKGKSKSACSDLLGNQPSSFSGSNLTLNDDWNKGTNVSFCVLPSRRPP 1578
                    + FG+  ++    + L  +  +++  ++L L          S   L S++PP
Sbjct: 316  --------QPFGLPPQASQGQAPLGTSPAAAYPHTSLQLP--------ASQSALQSQQPP 359

Query: 1579 -----PPPVPLLPPGTSPPVDPFTTL 1599
                 PP    +P    PP  P   L
Sbjct: 360  REQPLPPAPLAMPHIKPPPTTPIPQL 385


>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 90.9 bits (224), Expect = 9e-18
 Identities = 104/355 (29%), Positives = 139/355 (39%), Gaps = 74/355 (20%)

Query: 1049 DMEGDVDDYSAEVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPS---LPI 1105
            D E D D  SA+ + L  Q     + +G+  +PSS+P  +P Q PT   GP PS   +P 
Sbjct: 720  DNESDSDS-SAQQQMLQAQPPALQAPTGVTPAPSSAPPGTP-QLPT--PGPTPSATAVPP 775

Query: 1106 RPSRAPSRTPGPPSAQSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRP------ 1159
            + S   S+ P  P A ++P+        P   P +P  P  PP P P  PP +P      
Sbjct: 776  QGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSP-HPPLQPLTGSAG 834

Query: 1160 ---APPQRPPPPSGARSPAPTRKEFGGI----------GAPP-----------SPGVA-- 1193
               AP    PP  G   P P   + G +          G PP           SP  A  
Sbjct: 835  QPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYP 894

Query: 1194 RREMEAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAGYSTARPTIPPRAGVISAPQSHARA 1253
               ++ P S    +     R QP P A LA P    +    PT P     + APQ+H   
Sbjct: 895  HTSLQLPASQSALQSQQPPREQPLPPAPLAMP----HIKPPPTTP--IPQLPAPQAHKH- 947

Query: 1254 SAGRLTPESQSKTSETSKGSTFLPEP-LKPQAAFP---PQSSLPPPAQRLQEPLVPVAAP 1309
                  P   S  S  S  +   P P LKP ++     P S+ PPP Q            
Sbjct: 948  ------PPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQL----------- 990

Query: 1310 MPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQVKTNGISDGKRESPLKIDPF 1364
            MPQS P P+  +P QPP  ++S +  P  AS  P     G+     + P    PF
Sbjct: 991  MPQSQPLPS--SPAQPPGLTQSQNLPPPPASHPP----TGLHQVAPQPPFAQHPF 1039



 Score = 58.2 bits (139), Expect = 6e-08
 Identities = 99/441 (22%), Positives = 139/441 (31%), Gaps = 77/441 (17%)

Query: 1043 EVAADFDMEGDVDDYSAEVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPS 1102
            +VA+D +          + +E+   +  PS   G  +   S           I +    +
Sbjct: 653  KVASDTEEADRTSSKKTKTQEISRPN-SPSEGEGESSDSRSVNDEGSSDPKDIDQDNRST 711

Query: 1103 LPIRPSRAPSRTPGPPSAQSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPP 1162
             P  PS   + +    SAQ   + AQP        PA        P P   APP  P  P
Sbjct: 712  SPSIPSPQDNESDSDSSAQQQMLQAQP--------PALQAPTGVTPAPSS-APPGTPQLP 762

Query: 1163 QRPPPPSGARSPAPTRKEFGGIGAPPSPGVARREMEAPKSPGTTRKDNIGRSQPSPQAGL 1222
               P PS    P             P+   A  + +AP +P      +I ++        
Sbjct: 763  TPGPTPSATAVPPQ---------GSPTASQAPNQPQAPTAP--VPHTHIQQAPALHPQRP 811

Query: 1223 AGPGPAGYSTARPTIPPRAGVISAPQ--SHAR-------------ASAGRL-----TPES 1262
              P P  + +  P + P  G    P   SHA+               AG L      P+ 
Sbjct: 812  PSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQP 871

Query: 1263 QSKTSETSKGSTFLPEPLKPQAAFP--------PQSSLPPPAQRLQEPLVPVAAPMPQSG 1314
                 + S+G    P    P AA+P         QS+L       ++PL P    MP   
Sbjct: 872  FGLPPQASQGQA--PLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIK 929

Query: 1315 PQPNLETPPQPPPRSRSSHSLPSEASSQPQVKTNGISDGKRESPLKIDPFEDLSFNLLAV 1374
            P P    P  P P+   +H  P   S       N         P  + P   LS +    
Sbjct: 930  PPPTTPIPQLPAPQ---AHKHPPHLSGPSPFSMN----ANLPPPPALKPLSSLSTH-HPP 981

Query: 1375 SKAQLSVQTSPVPTPDPKRLIQLPSATQSNVLSSVSCMPTMPPIPARSQSQENMRSSPNP 1434
            S     +Q  P   P P    Q P  TQS           +PP PA        + +P P
Sbjct: 982  SAHPPPLQLMPQSQPLPSSPAQPPGLTQSQ---------NLPPPPASHPPTGLHQVAPQP 1032

Query: 1435 FITGLTRTNPFSDRTAAPGNP 1455
                     PF+     PG P
Sbjct: 1033 ---------PFAQHPFVPGGP 1044



 Score = 41.6 bits (96), Expect = 0.006
 Identities = 48/149 (32%), Positives = 59/149 (39%), Gaps = 18/149 (12%)

Query: 1066 PQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRP-SRAPSRTPGPPSAQSSP 1124
            P  L+P SS      PS+ P   P Q    S+ P+PS P +P     S+   PP A   P
Sbjct: 966  PPALKPLSSLSTHHPPSAHP--PPLQLMPQSQ-PLPSSPAQPPGLTQSQNLPPPPASHPP 1022

Query: 1125 IDAQPATPLPQKDPAQPLEPKRPPPPRPV---APPTRPAPP--QRPPPPSGARSPAPTRK 1179
                   P P      P  P  PPP  P    +  T PA P     PP SGA   A +  
Sbjct: 1023 TGLHQVAPQPPF-AQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGA---AASGG 1078

Query: 1180 EFGGIGAPPSPGVARRE-----MEAPKSP 1203
               G  + P P V  +E      E P+SP
Sbjct: 1079 SIAGGSSCPLPTVQIKEEALDDAEEPESP 1107



 Score = 39.3 bits (90), Expect = 0.031
 Identities = 47/155 (30%), Positives = 61/155 (39%), Gaps = 36/155 (23%)

Query: 1068 HLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVP-----SLPIRPSRAPSR---TPGPPS 1119
            H++P  ++ +   P+      P   P +S GP P     +LP  P+  P     T  PPS
Sbjct: 927  HIKPPPTTPIPQLPAPQAHKHP---PHLS-GPSPFSMNANLPPPPALKPLSSLSTHHPPS 982

Query: 1120 AQSSPIDAQPAT-PLPQKDPAQP---LEPKRPPPPRPVAPPT-----RPAPP--QRP--- 1165
            A   P+   P + PLP   PAQP    + +  PPP    PPT      P PP  Q P   
Sbjct: 983  AHPPPLQLMPQSQPLPSS-PAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVP 1041

Query: 1166 -------PPPSGARSPAPTRKEFGGIGAPPSPGVA 1193
                   PP   + S  P     G    PP  G A
Sbjct: 1042 GGPPPITPPTCPSTSTPPAGP--GTSAQPPCSGAA 1074



 Score = 34.7 bits (78), Expect = 0.77
 Identities = 83/386 (21%), Positives = 138/386 (35%), Gaps = 76/386 (19%)

Query: 1245 SAPQSHARASAGRLTPESQSKTSETSKGSTFLP--EPLKPQAAFPPQSSLPPPAQRLQEP 1302
            ++P +    S+GR +P + S +S  SK  T     + +K +A+ P +S+     +R +E 
Sbjct: 599  TSPINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSN-----KRQREK 653

Query: 1303 LVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQVKTNGISDGK-------R 1355
               VA+   ++    + +T  Q   R  S      E+S    V   G SD K        
Sbjct: 654  ---VASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRS 710

Query: 1356 ESPLKIDPFEDLSFNLLAVSKAQLSVQ---------TSPVPTPDPKRLIQLPSATQSNVL 1406
             SP    P ++ S +  +  +  L  Q          +P P+  P    QLP  T     
Sbjct: 711  TSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLP--TPGPTP 768

Query: 1407 SSVSCMPTMPPIPARSQSQENMRSSPNPFITGLTRTNPFSDRTAAPGNPFRAKSEESEAT 1466
            S+ +  P   P  +++ +Q    ++P P       T+        P  P           
Sbjct: 769  SATAVPPQGSPTASQAPNQPQAPTAPVP------HTHIQQAPALHPQRPP---------- 812

Query: 1467 SWFSKEEPVTISPFPSLQPLGHNKSRASSSL--------DGFKDSFDLQGQSTLKISNPK 1518
               S   P   SP P LQPL  +  + S+           G      LQ    L+   P 
Sbjct: 813  ---SPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPP 869

Query: 1519 GWVTFEEEEDFGVKGKSKSACSDLLGNQPSSFSGSNLTLNDDWNKGTNVSFCVLPSRRPP 1578
                    + FG+  ++    + L  +  +++  ++L L          S   L S++PP
Sbjct: 870  --------QPFGLPPQASQGQAPLGTSPAAAYPHTSLQLP--------ASQSALQSQQPP 913

Query: 1579 -----PPPVPLLPPGTSPPVDPFTTL 1599
                 PP    +P    PP  P   L
Sbjct: 914  REQPLPPAPLAMPHIKPPPTTPIPQL 939


>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 90.9 bits (224), Expect = 9e-18
 Identities = 104/355 (29%), Positives = 139/355 (39%), Gaps = 74/355 (20%)

Query: 1049 DMEGDVDDYSAEVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPS---LPI 1105
            D E D D  SA+ + L  Q     + +G+  +PSS+P  +P Q PT   GP PS   +P 
Sbjct: 720  DNESDSDS-SAQQQMLQAQPPALQAPTGVTPAPSSAPPGTP-QLPT--PGPTPSATAVPP 775

Query: 1106 RPSRAPSRTPGPPSAQSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRP------ 1159
            + S   S+ P  P A ++P+        P   P +P  P  PP P P  PP +P      
Sbjct: 776  QGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSP-HPPLQPLTGSAG 834

Query: 1160 ---APPQRPPPPSGARSPAPTRKEFGGI----------GAPP-----------SPGVA-- 1193
               AP    PP  G   P P   + G +          G PP           SP  A  
Sbjct: 835  QPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYP 894

Query: 1194 RREMEAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAGYSTARPTIPPRAGVISAPQSHARA 1253
               ++ P S    +     R QP P A LA P    +    PT P     + APQ+H   
Sbjct: 895  HTSLQLPASQSALQSQQPPREQPLPPAPLAMP----HIKPPPTTP--IPQLPAPQAHKH- 947

Query: 1254 SAGRLTPESQSKTSETSKGSTFLPEP-LKPQAAFP---PQSSLPPPAQRLQEPLVPVAAP 1309
                  P   S  S  S  +   P P LKP ++     P S+ PPP Q            
Sbjct: 948  ------PPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQL----------- 990

Query: 1310 MPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQVKTNGISDGKRESPLKIDPF 1364
            MPQS P P+  +P QPP  ++S +  P  AS  P     G+     + P    PF
Sbjct: 991  MPQSQPLPS--SPAQPPGLTQSQNLPPPPASHPP----TGLHQVAPQPPFAQHPF 1039



 Score = 58.2 bits (139), Expect = 6e-08
 Identities = 99/441 (22%), Positives = 139/441 (31%), Gaps = 77/441 (17%)

Query: 1043 EVAADFDMEGDVDDYSAEVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPS 1102
            +VA+D +          + +E+   +  PS   G  +   S           I +    +
Sbjct: 653  KVASDTEEADRTSSKKTKTQEISRPN-SPSEGEGESSDSRSVNDEGSSDPKDIDQDNRST 711

Query: 1103 LPIRPSRAPSRTPGPPSAQSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPP 1162
             P  PS   + +    SAQ   + AQP        PA        P P   APP  P  P
Sbjct: 712  SPSIPSPQDNESDSDSSAQQQMLQAQP--------PALQAPTGVTPAPSS-APPGTPQLP 762

Query: 1163 QRPPPPSGARSPAPTRKEFGGIGAPPSPGVARREMEAPKSPGTTRKDNIGRSQPSPQAGL 1222
               P PS    P             P+   A  + +AP +P      +I ++        
Sbjct: 763  TPGPTPSATAVPPQ---------GSPTASQAPNQPQAPTAP--VPHTHIQQAPALHPQRP 811

Query: 1223 AGPGPAGYSTARPTIPPRAGVISAPQ--SHAR-------------ASAGRL-----TPES 1262
              P P  + +  P + P  G    P   SHA+               AG L      P+ 
Sbjct: 812  PSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQP 871

Query: 1263 QSKTSETSKGSTFLPEPLKPQAAFP--------PQSSLPPPAQRLQEPLVPVAAPMPQSG 1314
                 + S+G    P    P AA+P         QS+L       ++PL P    MP   
Sbjct: 872  FGLPPQASQGQA--PLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIK 929

Query: 1315 PQPNLETPPQPPPRSRSSHSLPSEASSQPQVKTNGISDGKRESPLKIDPFEDLSFNLLAV 1374
            P P    P  P P+   +H  P   S       N         P  + P   LS +    
Sbjct: 930  PPPTTPIPQLPAPQ---AHKHPPHLSGPSPFSMN----ANLPPPPALKPLSSLSTH-HPP 981

Query: 1375 SKAQLSVQTSPVPTPDPKRLIQLPSATQSNVLSSVSCMPTMPPIPARSQSQENMRSSPNP 1434
            S     +Q  P   P P    Q P  TQS           +PP PA        + +P P
Sbjct: 982  SAHPPPLQLMPQSQPLPSSPAQPPGLTQSQ---------NLPPPPASHPPTGLHQVAPQP 1032

Query: 1435 FITGLTRTNPFSDRTAAPGNP 1455
                     PF+     PG P
Sbjct: 1033 ---------PFAQHPFVPGGP 1044



 Score = 41.6 bits (96), Expect = 0.006
 Identities = 48/149 (32%), Positives = 59/149 (39%), Gaps = 18/149 (12%)

Query: 1066 PQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRP-SRAPSRTPGPPSAQSSP 1124
            P  L+P SS      PS+ P   P Q    S+ P+PS P +P     S+   PP A   P
Sbjct: 966  PPALKPLSSLSTHHPPSAHP--PPLQLMPQSQ-PLPSSPAQPPGLTQSQNLPPPPASHPP 1022

Query: 1125 IDAQPATPLPQKDPAQPLEPKRPPPPRPV---APPTRPAPP--QRPPPPSGARSPAPTRK 1179
                   P P      P  P  PPP  P    +  T PA P     PP SGA   A +  
Sbjct: 1023 TGLHQVAPQPPF-AQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGA---AASGG 1078

Query: 1180 EFGGIGAPPSPGVARRE-----MEAPKSP 1203
               G  + P P V  +E      E P+SP
Sbjct: 1079 SIAGGSSCPLPTVQIKEEALDDAEEPESP 1107



 Score = 39.3 bits (90), Expect = 0.031
 Identities = 47/155 (30%), Positives = 61/155 (39%), Gaps = 36/155 (23%)

Query: 1068 HLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVP-----SLPIRPSRAPSR---TPGPPS 1119
            H++P  ++ +   P+      P   P +S GP P     +LP  P+  P     T  PPS
Sbjct: 927  HIKPPPTTPIPQLPAPQAHKHP---PHLS-GPSPFSMNANLPPPPALKPLSSLSTHHPPS 982

Query: 1120 AQSSPIDAQPAT-PLPQKDPAQP---LEPKRPPPPRPVAPPT-----RPAPP--QRP--- 1165
            A   P+   P + PLP   PAQP    + +  PPP    PPT      P PP  Q P   
Sbjct: 983  AHPPPLQLMPQSQPLPSS-PAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVP 1041

Query: 1166 -------PPPSGARSPAPTRKEFGGIGAPPSPGVA 1193
                   PP   + S  P     G    PP  G A
Sbjct: 1042 GGPPPITPPTCPSTSTPPAGP--GTSAQPPCSGAA 1074



 Score = 34.7 bits (78), Expect = 0.77
 Identities = 83/386 (21%), Positives = 138/386 (35%), Gaps = 76/386 (19%)

Query: 1245 SAPQSHARASAGRLTPESQSKTSETSKGSTFLP--EPLKPQAAFPPQSSLPPPAQRLQEP 1302
            ++P +    S+GR +P + S +S  SK  T     + +K +A+ P +S+     +R +E 
Sbjct: 599  TSPINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSN-----KRQREK 653

Query: 1303 LVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQVKTNGISDGK-------R 1355
               VA+   ++    + +T  Q   R  S      E+S    V   G SD K        
Sbjct: 654  ---VASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRS 710

Query: 1356 ESPLKIDPFEDLSFNLLAVSKAQLSVQ---------TSPVPTPDPKRLIQLPSATQSNVL 1406
             SP    P ++ S +  +  +  L  Q          +P P+  P    QLP  T     
Sbjct: 711  TSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLP--TPGPTP 768

Query: 1407 SSVSCMPTMPPIPARSQSQENMRSSPNPFITGLTRTNPFSDRTAAPGNPFRAKSEESEAT 1466
            S+ +  P   P  +++ +Q    ++P P       T+        P  P           
Sbjct: 769  SATAVPPQGSPTASQAPNQPQAPTAPVP------HTHIQQAPALHPQRPP---------- 812

Query: 1467 SWFSKEEPVTISPFPSLQPLGHNKSRASSSL--------DGFKDSFDLQGQSTLKISNPK 1518
               S   P   SP P LQPL  +  + S+           G      LQ    L+   P 
Sbjct: 813  ---SPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPP 869

Query: 1519 GWVTFEEEEDFGVKGKSKSACSDLLGNQPSSFSGSNLTLNDDWNKGTNVSFCVLPSRRPP 1578
                    + FG+  ++    + L  +  +++  ++L L          S   L S++PP
Sbjct: 870  --------QPFGLPPQASQGQAPLGTSPAAAYPHTSLQLP--------ASQSALQSQQPP 913

Query: 1579 -----PPPVPLLPPGTSPPVDPFTTL 1599
                 PP    +P    PP  P   L
Sbjct: 914  REQPLPPAPLAMPHIKPPPTTPIPQL 939


>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
          Length = 416

 Score = 90.5 bits (223), Expect = 1e-17
 Identities = 86/305 (28%), Positives = 109/305 (35%), Gaps = 49/305 (16%)

Query: 1071 PSSSSGLGTSPSSSPRTSPCQSPTISEGPVP---SLPIRPSRAPSRTPGPP-----SAQS 1122
            P      G  P      SP   P   +GP P   + P  P   P +  GPP       Q 
Sbjct: 93   PPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQG 152

Query: 1123 SPIDAQPATPLPQKDP------AQPLEPKRPPPP---RPVAPPTRPAPPQRPPPPSGAR- 1172
             P   +P  P PQ D       + P +P+ PPP    +P  PP  P  PQ PPP  G + 
Sbjct: 153  PPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKP 212

Query: 1173 -SPAPTRKEFGGIGAPPSPGVARREMEAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAGYS 1231
              P P  K  G     P P    +   A   PG  +        P PQ G    GP    
Sbjct: 213  QGPPPPGKPQG-----PPPQGDNKSQSARSPPGKPQG-------PPPQGGNQPQGPPPPP 260

Query: 1232 TARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSS 1291
                  PP+ G  + PQ        +  P      S +S+     P+   PQ    PQ  
Sbjct: 261  GKPQGPPPQGG--NKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGP 318

Query: 1292 LPPPAQRLQEPLVPVAAPMPQSGPQPNLETPP----QPPP----RSRSSHSLPSEASSQP 1343
             PPP +           P PQ G +P    PP     PPP    +SRS+ S P +    P
Sbjct: 319  PPPPGKP--------QGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGPP 370

Query: 1344 QVKTN 1348
            Q + N
Sbjct: 371  QQEGN 375



 Score = 87.4 bits (215), Expect = 1e-16
 Identities = 83/288 (28%), Positives = 109/288 (37%), Gaps = 55/288 (19%)

Query: 1080 SPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQPATPLPQKDPA 1139
            SP   P+  P Q     +GP P  P +P   P +    P  Q  P   +P  P PQ D +
Sbjct: 52   SPPGKPQGPPPQGGNQPQGPPPP-PGKPQGPPPQGGNKP--QGPPPPGKPQGPPPQGDKS 108

Query: 1140 Q-----PLEPKRPPPP---RPVAPPTRPAPPQRPPPPSGARSPAPTRKEFGGIGAPPSPG 1191
            +     P +P+ PPP    +P  PP  P  PQ PPP  G +   P           P PG
Sbjct: 109  RSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGP-----------PPPG 157

Query: 1192 VARREMEAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAGYST--------ARPTIPPRAGV 1243
                    P+ P   + DN  RS  SP     GP P G +          +P  PP  G 
Sbjct: 158  -------KPQGP-PPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGG 209

Query: 1244 ISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQEPL 1303
             + PQ        +  P      S++++     P+   PQ    PQ   PPP +      
Sbjct: 210  -NKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKP----- 263

Query: 1304 VPVAAPMPQSGPQPNLETPP----QPPP----RSRSSHSLPSEASSQP 1343
                 P PQ G +P    PP     PPP    +SRSS S P +    P
Sbjct: 264  ---QGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPP 308



 Score = 78.2 bits (191), Expect = 6e-14
 Identities = 77/275 (28%), Positives = 102/275 (37%), Gaps = 39/275 (14%)

Query: 1070 QPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQP 1129
            Q  + S    SP   P+  P Q     +GP P  P +P   P +    P  Q  P   +P
Sbjct: 165  QGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPP-PGKPQGPPPQGGNKP--QGPPPPGKP 221

Query: 1130 ATPLPQKDP------AQPLEPKRPPPP---RPVAPPTRPAPPQRPPPPSGARS---PAPT 1177
              P PQ D       + P +P+ PPP    +P  PP  P  PQ PPP  G +    P P 
Sbjct: 222  QGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPG 281

Query: 1178 RKEFGGIGAPPSPGVARREMEAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAGYSTARPTI 1237
            + +    G PP  G   R   +P  PG  +        P PQ G    GP          
Sbjct: 282  KPQ----GPPPQGGSKSRSSRSP--PGKPQG-------PPPQGGNQPQGPPPPPGKPQGP 328

Query: 1238 PPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQ 1297
            PP+ G  + PQ        +  P      S +++     P+    Q    PQ   PP   
Sbjct: 329  PPQGG--NKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGG 386

Query: 1298 RLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSS 1332
              Q+P  P A        QP  + PP+PP   R S
Sbjct: 387  NPQQPQAPPAG-------QP--QGPPRPPQGGRPS 412



 Score = 75.5 bits (184), Expect = 4e-13
 Identities = 69/245 (28%), Positives = 92/245 (37%), Gaps = 35/245 (14%)

Query: 1112 SRTPGPPSAQSSPIDAQP-ATPLPQKDPAQPLEPKRPPPP---RPVAPPTRPAPPQRPPP 1167
            S+   P     +P  A P     PQ  P+ P +P+ PPP    +P  PP  P  PQ PPP
Sbjct: 24   SQEESPSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPP 83

Query: 1168 PSGARSPAPTRKEFGGIGAPPSPGVARREMEAPKSPGTTRKDNIGRSQ-PSPQAGLAGPG 1226
              G +   P        G P  P     +  +P+SP        G+ Q P PQ G    G
Sbjct: 84   QGGNKPQGPPPP-----GKPQGPPPQGDKSRSPRSPP-------GKPQGPPPQGGNQPQG 131

Query: 1227 PAGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAF 1286
            P          PP+ G  + PQ        +  P      S +S+     P+   PQ   
Sbjct: 132  PPPPPGKPQGPPPQGG--NKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGN 189

Query: 1287 PPQSSLPPPAQRLQEPLVPVAAPMPQSGPQPNLETPP----QPPP----RSRSSHSLPSE 1338
             PQ   PPP +           P PQ G +P    PP     PPP    +S+S+ S P +
Sbjct: 190  QPQGPPPPPGKP--------QGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGK 241

Query: 1339 ASSQP 1343
                P
Sbjct: 242  PQGPP 246



 Score = 55.8 bits (133), Expect = 3e-07
 Identities = 40/136 (29%), Positives = 48/136 (35%), Gaps = 12/136 (8%)

Query: 1070 QPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQP 1129
            Q  S S    SP   P+  P Q     +GP P         P +  GPP    +     P
Sbjct: 289  QGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPP--------PGKPQGPPPQGGNKPQGPP 340

Query: 1130 ATPLPQKDPAQ---PLEPKRPPPPRPVAPPTRPAP-PQRPPPPSGARSPAPTRKEFGGIG 1185
                PQ  P Q        R PP +P  PP +    PQ PPPP+G     P     G   
Sbjct: 341  PPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQ 400

Query: 1186 APPSPGVARREMEAPK 1201
             PP P    R    P+
Sbjct: 401  GPPRPPQGGRPSRPPQ 416



 Score = 55.1 bits (131), Expect = 5e-07
 Identities = 53/181 (29%), Positives = 68/181 (37%), Gaps = 23/181 (12%)

Query: 1066 PQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPS--LPIRPSRAPSRTP-GPPSAQS 1122
            PQ   P      G  P    +      P   +GP P      R SR+P   P GPP    
Sbjct: 253  PQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGG 312

Query: 1123 SPIDAQPATPLPQKDPAQPLEPKRPPPP---RPVAPPTRPAPPQRPPPPSGARSPAPTRK 1179
            +          PQ  P  P +P+ PPP    +P  PP  P  PQ PPP  G++S    R 
Sbjct: 313  NQ---------PQGPPPPPGKPQGPPPQGGNKPQGPPP-PGKPQGPPPQGGSKS----RS 358

Query: 1180 EFGGIGAPPSPGVARREMEAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAGYSTARPTIPP 1239
                 G P  P   ++E   P+ P      N  + Q  P     GP P      RP+ PP
Sbjct: 359  ARSPPGKPQGP--PQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGP-PRPPQGGRPSRPP 415

Query: 1240 R 1240
            +
Sbjct: 416  Q 416



 Score = 32.0 bits (71), Expect = 5.0
 Identities = 26/80 (32%), Positives = 31/80 (38%), Gaps = 13/80 (16%)

Query: 1277 PEPLKPQAAFPPQSSL----PPPAQRLQEP-------LVPVAAPMPQSGPQPNLETPPQ- 1324
            P P KPQ   PPQ       PPP  + Q P         P + P    GP P     PQ 
Sbjct: 73   PPPGKPQGP-PPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQG 131

Query: 1325 PPPRSRSSHSLPSEASSQPQ 1344
            PPP        P +  ++PQ
Sbjct: 132  PPPPPGKPQGPPPQGGNKPQ 151


>gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [Homo
            sapiens]
          Length = 1636

 Score = 89.7 bits (221), Expect = 2e-17
 Identities = 97/385 (25%), Positives = 135/385 (35%), Gaps = 55/385 (14%)

Query: 1071 PSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQPA 1130
            P+ +  LG  P SSP+     SP +  GP P +   PS  P +  GP  A +     +PA
Sbjct: 825  PAYTPELGLVPRSSPQHGVVSSPYVGVGPAPPVAGLPSAPPPQFSGPELAMA----VRPA 880

Query: 1131 T--------PLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRKEFG 1182
            T        P+P     +P     PPPP    PP +P P      P+GA+ P P +  F 
Sbjct: 881  TTTVDSIQAPIPSHTAPRPNPTPAPPPPCFPVPPPQPLPTPY-TYPAGAKQPIPAQHHFS 939

Query: 1183 GIGAP---PSPGVARREMEAPKSPGTTRKDNIGRSQPSP--QAGLAGPGPAGYSTARPTI 1237
              G P   P+P +  +    P+   +         QP P     L  P   G    +   
Sbjct: 940  S-GIPAGFPAPRIGPQPQPHPQPHPSQAFGPQPPQQPLPLQHPHLFPPQAPGLLPPQSPY 998

Query: 1238 P--PRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPP 1295
            P  P+ GV+  P         +L P           G+   P P  PQ   PP +  P P
Sbjct: 999  PYAPQPGVLGQPPPPLHT---QLYPGPAQDPLPAHSGALPFPSPGPPQPPHPPLAYGPAP 1055

Query: 1296 AQRLQEP---------------------LVPVAAPMPQSGPQPNLETPPQPPPRSRSSHS 1334
            + R   P                     LVP  AP P  GP P      +PPP  R   +
Sbjct: 1056 STRPMGPQAAPLTIRGPSSAGQSTPSPHLVPSPAPSPGPGPVPPRPPAAEPPPCLRRGAA 1115

Query: 1335 LPSEASSQPQVKTNGISDGKRESPL----KIDPFEDLSFNLLAVSKAQLSVQTSPVPTPD 1390
                 SS P+ +  G        PL    K+D  E      L +      ++  P   P+
Sbjct: 1116 AADLLSSSPESQHGGTQSPGGGQPLLQPTKVDAAEGRRPQALRL------IERDPYEHPE 1169

Query: 1391 PKRLIQLPSATQSNVLSSVSCMPTM 1415
              R +Q         L  V  + T+
Sbjct: 1170 RLRQLQQELEAFRGQLGDVGALDTV 1194



 Score = 60.1 bits (144), Expect = 2e-08
 Identities = 94/382 (24%), Positives = 119/382 (31%), Gaps = 92/382 (24%)

Query: 1098 GPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQPATPLPQKDPAQPLEPKRPPP-PRPVAPP 1156
            G    L   PS  PS T   P   S P+      P     P Q ++P+ P P   PVAP 
Sbjct: 764  GSATPLHFPPSPFPSSTGPGPHYLSGPLP-----PGTYSGPTQLIQPRAPGPHAMPVAPG 818

Query: 1157 TR--PAPPQRPP--------PPSGARS-------PAPTRKEFGGIGAPPSPGVARREMEA 1199
                PAP   P         P  G  S       PAP      G+ + P P  +  E+  
Sbjct: 819  PALYPAPAYTPELGLVPRSSPQHGVVSSPYVGVGPAPP---VAGLPSAPPPQFSGPELAM 875

Query: 1200 PKSPGTTRKDNIGRSQPSPQAGLAGPGPAGYSTARPTIPPRAGVISAPQSHARASAGRLT 1259
               P TT  D+I    PS  A    P PA      P +PP                    
Sbjct: 876  AVRPATTTVDSIQAPIPSHTAPRPNPTPAPPPPCFP-VPP-------------------- 914

Query: 1260 PESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQEPLVPVAAPMPQSGPQPNL 1319
                             P+PL     +P  +  P PAQ      +P   P P+ GPQ   
Sbjct: 915  -----------------PQPLPTPYTYPAGAKQPIPAQHHFSSGIPAGFPAPRIGPQ--- 954

Query: 1320 ETPPQPPPRSRSSHSLPSEASSQP---------QVKTNGISDGKRESPLKIDPFEDLSFN 1370
               PQP P+   S +   +   QP           +  G+   +   P    P       
Sbjct: 955  ---PQPHPQPHPSQAFGPQPPQQPLPLQHPHLFPPQAPGLLPPQSPYPYAPQP------G 1005

Query: 1371 LLAVSKAQLSVQTSPVPTPDPKRLIQLPSATQSNVLSSVSCMPTMPPIPARSQSQENMRS 1430
            +L      L  Q  P P  DP     LP+   S  L   S  P  PP P  +        
Sbjct: 1006 VLGQPPPPLHTQLYPGPAQDP-----LPA--HSGALPFPSPGPPQPPHPPLAYGPAPSTR 1058

Query: 1431 SPNPFITGLTRTNPFSDRTAAP 1452
               P    LT   P S   + P
Sbjct: 1059 PMGPQAAPLTIRGPSSAGQSTP 1080



 Score = 48.1 bits (113), Expect = 7e-05
 Identities = 40/120 (33%), Positives = 46/120 (38%), Gaps = 24/120 (20%)

Query: 1057 YSAEVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSL-PIRPSRAPSRTP 1115
            Y    ++ LP H      SG    PS  P   P   P ++ GP PS  P+ P  AP    
Sbjct: 1019 YPGPAQDPLPAH------SGALPFPSPGPPQPP--HPPLAYGPAPSTRPMGPQAAPLTIR 1070

Query: 1116 GPPSAQSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPA 1175
            GP SA  S       TP P   P+        P P P   P  P PP   PPP   R  A
Sbjct: 1071 GPSSAGQS-------TPSPHLVPS--------PAPSPGPGPVPPRPPAAEPPPCLRRGAA 1115



 Score = 43.5 bits (101), Expect = 0.002
 Identities = 48/186 (25%), Positives = 68/186 (36%), Gaps = 22/186 (11%)

Query: 1061 VEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEG---PVPSLPIRPSRAPSRTPGP 1117
            VE++L +H  P     L ++  S     P  S  +  G   P+ S+    ++   R   P
Sbjct: 1453 VEQVLQRHGVPPPCKPLASASISQKNHLPQDSQDLVLGGDVPISSIQATIAKLSIR---P 1509

Query: 1118 PSAQSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPT 1177
            P    SP+ + P           P EP   PP     P + P P   PPP S     AP 
Sbjct: 1510 PGGLESPVASLPG----------PAEPPGLPPAS--LPESTPIPSSSPPPLSSPLPEAPQ 1557

Query: 1178 RKEFGGIGAPPSPGVARREME--APKSPGTTRKDNI--GRSQPSPQAGLAGPGPAGYSTA 1233
             KE   +   PS G     +E  A  +P     D+   G+ + S    L      G    
Sbjct: 1558 PKEEPPVPEAPSSGPPSSSLELLASLTPEAFSLDSSLRGKQRMSKHNFLQAHNGQGLRAT 1617

Query: 1234 RPTIPP 1239
            RP+  P
Sbjct: 1618 RPSDDP 1623



 Score = 34.3 bits (77), Expect = 1.0
 Identities = 19/61 (31%), Positives = 28/61 (45%), Gaps = 2/61 (3%)

Query: 1282 PQAAFPPQSSLP--PPAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEA 1339
            P A+ P  +  P  PPA   +   +P ++P P S P P    P + PP   +  S P  +
Sbjct: 1516 PVASLPGPAEPPGLPPASLPESTPIPSSSPPPLSSPLPEAPQPKEEPPVPEAPSSGPPSS 1575

Query: 1340 S 1340
            S
Sbjct: 1576 S 1576



 Score = 33.9 bits (76), Expect = 1.3
 Identities = 24/70 (34%), Positives = 34/70 (48%), Gaps = 4/70 (5%)

Query: 1276 LPEPLKPQAAFPPQSSLPPPAQRLQEPLVPVAAPMPQSGPQPNLETP-PQPPPRSRSSHS 1334
            LP P +P     P +SLP           P+++P+P++ PQP  E P P+ P     S S
Sbjct: 1520 LPGPAEPPGL--PPASLPESTPIPSSSPPPLSSPLPEA-PQPKEEPPVPEAPSSGPPSSS 1576

Query: 1335 LPSEASSQPQ 1344
            L   AS  P+
Sbjct: 1577 LELLASLTPE 1586


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.132    0.393 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 71,787,424
Number of Sequences: 37866
Number of extensions: 4309196
Number of successful extensions: 84872
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 781
Number of HSP's successfully gapped in prelim test: 2496
Number of HSP's that attempted gapping in prelim test: 26412
Number of HSP's gapped (non-prelim): 27131
length of query: 1612
length of database: 18,247,518
effective HSP length: 116
effective length of query: 1496
effective length of database: 13,855,062
effective search space: 20727172752
effective search space used: 20727172752
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 69 (31.2 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

CSHL Press