Guide to the Human Genome
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Search of human proteins with 237681065

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|237681065 cannabinoid receptor 1 isoform b [Homo sapiens]
         (439 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|237681065 cannabinoid receptor 1 isoform b [Homo sapiens]          872   0.0  
gi|237681179 cannabinoid receptor 1 isoform a [Homo sapiens]          855   0.0  
gi|237681175 cannabinoid receptor 1 isoform a [Homo sapiens]          855   0.0  
gi|237681173 cannabinoid receptor 1 isoform a [Homo sapiens]          855   0.0  
gi|237681067 cannabinoid receptor 1 isoform a [Homo sapiens]          855   0.0  
gi|38683844 cannabinoid receptor 1 isoform a [Homo sapiens]           855   0.0  
gi|4502929 cannabinoid receptor 2 (macrophage) [Homo sapiens]         277   1e-74
gi|16950638 lysophosphatidic acid receptor 1 [Homo sapiens]           133   4e-31
gi|16950636 lysophosphatidic acid receptor 1 [Homo sapiens]           133   4e-31
gi|13027636 sphingosine-1-phosphate receptor 1 [Homo sapiens]         130   2e-30
gi|6912348 lysophosphatidic acid receptor 3 [Homo sapiens]            129   4e-30
gi|38788193 sphingosine-1-phosphate receptor 3 [Homo sapiens]         128   9e-30
gi|4503459 sphingosine-1-phosphate receptor 4 precursor [Homo sa...   119   7e-27
gi|7305013 lysophosphatidic acid receptor 2 [Homo sapiens]            117   3e-26
gi|13540517 endothelial differentiation, sphingolipid G-protein-...   116   5e-26
gi|4885295 G protein-coupled receptor 12 [Homo sapiens]               115   1e-25
gi|4885325 G protein-coupled receptor 3 [Homo sapiens]                108   1e-23
gi|111118990 alpha-1A-adrenergic receptor isoform 4 [Homo sapiens]    104   2e-22
gi|111118992 alpha-1A-adrenergic receptor isoform 1 [Homo sapiens]    104   2e-22
gi|111118986 alpha-1A-adrenergic receptor isoform 2 [Homo sapiens]    104   2e-22
gi|111118988 alpha-1A-adrenergic receptor isoform 3 [Homo sapiens]    104   2e-22
gi|134244587 endothelial differentiation, sphingolipid G-protein...   103   3e-22
gi|4885341 G protein-coupled receptor 6 [Homo sapiens]                103   3e-22
gi|4505127 melanocortin 2 receptor [Homo sapiens]                     100   3e-21
gi|4501959 alpha-1B-adrenergic receptor [Homo sapiens]                 97   4e-20
gi|5174535 melanocortin 5 receptor [Homo sapiens]                      96   8e-20
gi|119508433 melanocortin 4 receptor [Homo sapiens]                    94   3e-19
gi|170671732 melanocortin 3 receptor [Homo sapiens]                    94   3e-19
gi|4501951 adenosine A2b receptor [Homo sapiens]                       94   3e-19
gi|4501957 alpha-1D-adrenergic receptor [Homo sapiens]                 94   3e-19

>gi|237681065 cannabinoid receptor 1 isoform b [Homo sapiens]
          Length = 439

 Score =  872 bits (2252), Expect = 0.0
 Identities = 439/439 (100%), Positives = 439/439 (100%)

Query: 1   MKSILDGLADTTFRTITTDLLGSPFQEKMTAGDNPQLVPADQVNITEFYNKSLSSFKENE 60
           MKSILDGLADTTFRTITTDLLGSPFQEKMTAGDNPQLVPADQVNITEFYNKSLSSFKENE
Sbjct: 1   MKSILDGLADTTFRTITTDLLGSPFQEKMTAGDNPQLVPADQVNITEFYNKSLSSFKENE 60

Query: 61  ENIQCGENFMDIECFMVLNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSY 120
           ENIQCGENFMDIECFMVLNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSY
Sbjct: 61  ENIQCGENFMDIECFMVLNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSY 120

Query: 121 HFIGSLAVADLLGSVIFVYSFIDFHVFHRKDSRNVFLFKLGGVTASFTASVGSLFLTAID 180
           HFIGSLAVADLLGSVIFVYSFIDFHVFHRKDSRNVFLFKLGGVTASFTASVGSLFLTAID
Sbjct: 121 HFIGSLAVADLLGSVIFVYSFIDFHVFHRKDSRNVFLFKLGGVTASFTASVGSLFLTAID 180

Query: 181 RYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDE 240
           RYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDE
Sbjct: 181 RYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDE 240

Query: 241 TYLMFWIGVTSVLLLFIVYAYMYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPD 300
           TYLMFWIGVTSVLLLFIVYAYMYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPD
Sbjct: 241 TYLMFWIGVTSVLLLFIVYAYMYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPD 300

Query: 301 QARMDIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVN 360
           QARMDIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVN
Sbjct: 301 QARMDIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVN 360

Query: 361 PIIYALRSKDLRHAFRSMFPSCEGTAQPLDNSMGDSDCLHKHANNAASVHRAAESCIKST 420
           PIIYALRSKDLRHAFRSMFPSCEGTAQPLDNSMGDSDCLHKHANNAASVHRAAESCIKST
Sbjct: 361 PIIYALRSKDLRHAFRSMFPSCEGTAQPLDNSMGDSDCLHKHANNAASVHRAAESCIKST 420

Query: 421 VKIAKVTMSVSTDTSAEAL 439
           VKIAKVTMSVSTDTSAEAL
Sbjct: 421 VKIAKVTMSVSTDTSAEAL 439


>gi|237681179 cannabinoid receptor 1 isoform a [Homo sapiens]
          Length = 472

 Score =  855 bits (2208), Expect = 0.0
 Identities = 439/472 (93%), Positives = 439/472 (93%), Gaps = 33/472 (6%)

Query: 1   MKSILDGLADTTFRTITTDLL---------------------------------GSPFQE 27
           MKSILDGLADTTFRTITTDLL                                 GSPFQE
Sbjct: 1   MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQE 60

Query: 28  KMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIA 87
           KMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIA
Sbjct: 61  KMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIA 120

Query: 88  VLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVF 147
           VLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVF
Sbjct: 121 VLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVF 180

Query: 148 HRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLM 207
           HRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLM
Sbjct: 181 HRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLM 240

Query: 208 WTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWK 267
           WTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWK
Sbjct: 241 WTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWK 300

Query: 268 AHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLL 327
           AHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLL
Sbjct: 301 AHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLL 360

Query: 328 AIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQ 387
           AIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQ
Sbjct: 361 AIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQ 420

Query: 388 PLDNSMGDSDCLHKHANNAASVHRAAESCIKSTVKIAKVTMSVSTDTSAEAL 439
           PLDNSMGDSDCLHKHANNAASVHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
Sbjct: 421 PLDNSMGDSDCLHKHANNAASVHRAAESCIKSTVKIAKVTMSVSTDTSAEAL 472


>gi|237681175 cannabinoid receptor 1 isoform a [Homo sapiens]
          Length = 472

 Score =  855 bits (2208), Expect = 0.0
 Identities = 439/472 (93%), Positives = 439/472 (93%), Gaps = 33/472 (6%)

Query: 1   MKSILDGLADTTFRTITTDLL---------------------------------GSPFQE 27
           MKSILDGLADTTFRTITTDLL                                 GSPFQE
Sbjct: 1   MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQE 60

Query: 28  KMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIA 87
           KMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIA
Sbjct: 61  KMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIA 120

Query: 88  VLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVF 147
           VLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVF
Sbjct: 121 VLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVF 180

Query: 148 HRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLM 207
           HRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLM
Sbjct: 181 HRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLM 240

Query: 208 WTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWK 267
           WTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWK
Sbjct: 241 WTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWK 300

Query: 268 AHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLL 327
           AHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLL
Sbjct: 301 AHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLL 360

Query: 328 AIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQ 387
           AIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQ
Sbjct: 361 AIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQ 420

Query: 388 PLDNSMGDSDCLHKHANNAASVHRAAESCIKSTVKIAKVTMSVSTDTSAEAL 439
           PLDNSMGDSDCLHKHANNAASVHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
Sbjct: 421 PLDNSMGDSDCLHKHANNAASVHRAAESCIKSTVKIAKVTMSVSTDTSAEAL 472


>gi|237681173 cannabinoid receptor 1 isoform a [Homo sapiens]
          Length = 472

 Score =  855 bits (2208), Expect = 0.0
 Identities = 439/472 (93%), Positives = 439/472 (93%), Gaps = 33/472 (6%)

Query: 1   MKSILDGLADTTFRTITTDLL---------------------------------GSPFQE 27
           MKSILDGLADTTFRTITTDLL                                 GSPFQE
Sbjct: 1   MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQE 60

Query: 28  KMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIA 87
           KMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIA
Sbjct: 61  KMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIA 120

Query: 88  VLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVF 147
           VLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVF
Sbjct: 121 VLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVF 180

Query: 148 HRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLM 207
           HRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLM
Sbjct: 181 HRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLM 240

Query: 208 WTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWK 267
           WTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWK
Sbjct: 241 WTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWK 300

Query: 268 AHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLL 327
           AHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLL
Sbjct: 301 AHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLL 360

Query: 328 AIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQ 387
           AIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQ
Sbjct: 361 AIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQ 420

Query: 388 PLDNSMGDSDCLHKHANNAASVHRAAESCIKSTVKIAKVTMSVSTDTSAEAL 439
           PLDNSMGDSDCLHKHANNAASVHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
Sbjct: 421 PLDNSMGDSDCLHKHANNAASVHRAAESCIKSTVKIAKVTMSVSTDTSAEAL 472


>gi|237681067 cannabinoid receptor 1 isoform a [Homo sapiens]
          Length = 472

 Score =  855 bits (2208), Expect = 0.0
 Identities = 439/472 (93%), Positives = 439/472 (93%), Gaps = 33/472 (6%)

Query: 1   MKSILDGLADTTFRTITTDLL---------------------------------GSPFQE 27
           MKSILDGLADTTFRTITTDLL                                 GSPFQE
Sbjct: 1   MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQE 60

Query: 28  KMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIA 87
           KMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIA
Sbjct: 61  KMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIA 120

Query: 88  VLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVF 147
           VLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVF
Sbjct: 121 VLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVF 180

Query: 148 HRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLM 207
           HRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLM
Sbjct: 181 HRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLM 240

Query: 208 WTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWK 267
           WTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWK
Sbjct: 241 WTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWK 300

Query: 268 AHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLL 327
           AHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLL
Sbjct: 301 AHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLL 360

Query: 328 AIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQ 387
           AIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQ
Sbjct: 361 AIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQ 420

Query: 388 PLDNSMGDSDCLHKHANNAASVHRAAESCIKSTVKIAKVTMSVSTDTSAEAL 439
           PLDNSMGDSDCLHKHANNAASVHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
Sbjct: 421 PLDNSMGDSDCLHKHANNAASVHRAAESCIKSTVKIAKVTMSVSTDTSAEAL 472


>gi|38683844 cannabinoid receptor 1 isoform a [Homo sapiens]
          Length = 472

 Score =  855 bits (2208), Expect = 0.0
 Identities = 439/472 (93%), Positives = 439/472 (93%), Gaps = 33/472 (6%)

Query: 1   MKSILDGLADTTFRTITTDLL---------------------------------GSPFQE 27
           MKSILDGLADTTFRTITTDLL                                 GSPFQE
Sbjct: 1   MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQE 60

Query: 28  KMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIA 87
           KMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIA
Sbjct: 61  KMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIA 120

Query: 88  VLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVF 147
           VLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVF
Sbjct: 121 VLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVF 180

Query: 148 HRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLM 207
           HRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLM
Sbjct: 181 HRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLM 240

Query: 208 WTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWK 267
           WTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWK
Sbjct: 241 WTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWK 300

Query: 268 AHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLL 327
           AHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLL
Sbjct: 301 AHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLL 360

Query: 328 AIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQ 387
           AIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQ
Sbjct: 361 AIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQ 420

Query: 388 PLDNSMGDSDCLHKHANNAASVHRAAESCIKSTVKIAKVTMSVSTDTSAEAL 439
           PLDNSMGDSDCLHKHANNAASVHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
Sbjct: 421 PLDNSMGDSDCLHKHANNAASVHRAAESCIKSTVKIAKVTMSVSTDTSAEAL 472


>gi|4502929 cannabinoid receptor 2 (macrophage) [Homo sapiens]
          Length = 360

 Score =  277 bits (709), Expect = 1e-74
 Identities = 142/298 (47%), Positives = 196/298 (65%), Gaps = 15/298 (5%)

Query: 75  FMVLNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGS 134
           +M+L+  Q+ A+AVL   LG  + LEN+ VL +IL S  LR +PSY FIGSLA AD L S
Sbjct: 25  YMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLAS 84

Query: 135 VIFVYSFIDFHVFHRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRI 194
           V+F  SF++FHVFH  DS+ VFL K+G VT +FTASVGSL LTAIDRY+ +  P +YK +
Sbjct: 85  VVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKAL 144

Query: 195 VTRPKAVVAFCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLL 254
           +TR +A+V   +MW ++ +++ LPL+GW C      CS++FP I   YL+ W+   + L 
Sbjct: 145 LTRGRALVTLGIMWVLSALVSYLPLMGWTC--CPRPCSELFPLIPNDYLLSWLLFIAFLF 202

Query: 255 LFIVYAYMYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVL 314
             I+Y Y ++LWKAH H   +             S     QV    + R+D+RLAKTL L
Sbjct: 203 SGIIYTYGHVLWKAHQHVASL-------------SGHQDRQVPGMARMRLDVRLAKTLGL 249

Query: 315 ILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLR 372
           +L VL+ICW P+LA+M + +   ++  +K  FAFCSMLCL+NS VNP+IYALRS ++R
Sbjct: 250 VLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIR 307


>gi|16950638 lysophosphatidic acid receptor 1 [Homo sapiens]
          Length = 364

 Score =  133 bits (334), Expect = 4e-31
 Identities = 103/369 (27%), Positives = 172/369 (46%), Gaps = 41/369 (11%)

Query: 26  QEKMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLA 85
           Q + TA + PQ           FYN+S++ F          E           N   +L 
Sbjct: 13  QPQFTAMNEPQC----------FYNESIAFFYNRSGKHLATE----------WNTVSKLV 52

Query: 86  IAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFH 145
           +  L +T+  F +L NLLV+  I  +R     P Y+ + +LA AD    + + Y   +  
Sbjct: 53  MG-LGITVCIFIMLANLLVMVAIYVNRRFHF-PIYYLMANLAAADFFAGLAYFYLMFNTG 110

Query: 146 VFHRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFC 205
              R+ + + +L + G +  S TASV +L   AI+R+I++ R   + R+  R + VV   
Sbjct: 111 PNTRRLTVSTWLLRQGLIDTSLTASVANLLAIAIERHITVFRMQLHTRMSNR-RVVVVIV 169

Query: 206 LMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYIL 265
           ++WT+AIV+  +P +GWNC      CS++ P   ++YL+FW     V  + +V  Y +I 
Sbjct: 170 VIWTMAIVMGAIPSVGWNCICDIENCSNMAPLYSDSYLVFWAIFNLVTFVVMVVLYAHIF 229

Query: 266 WKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGP 325
                  +RM +         H+S   + + T        + L KT+V++L   IICW P
Sbjct: 230 GYVRQRTMRMSR---------HSSGPRRNRDTM-------MSLLKTVVIVLGAFIICWTP 273

Query: 326 LLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGT 385
            L +++ DV      ++     F  +L   NS +NPIIY+ R K++   FR +   C+ +
Sbjct: 274 GLVLLLLDVCCPQCDVL-AYEKFFLLLAEFNSAMNPIIYSYRDKEMSATFRQIL-CCQRS 331

Query: 386 AQPLDNSMG 394
             P   + G
Sbjct: 332 ENPTGPTEG 340


>gi|16950636 lysophosphatidic acid receptor 1 [Homo sapiens]
          Length = 364

 Score =  133 bits (334), Expect = 4e-31
 Identities = 103/369 (27%), Positives = 172/369 (46%), Gaps = 41/369 (11%)

Query: 26  QEKMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLA 85
           Q + TA + PQ           FYN+S++ F          E           N   +L 
Sbjct: 13  QPQFTAMNEPQC----------FYNESIAFFYNRSGKHLATE----------WNTVSKLV 52

Query: 86  IAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFH 145
           +  L +T+  F +L NLLV+  I  +R     P Y+ + +LA AD    + + Y   +  
Sbjct: 53  MG-LGITVCIFIMLANLLVMVAIYVNRRFHF-PIYYLMANLAAADFFAGLAYFYLMFNTG 110

Query: 146 VFHRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFC 205
              R+ + + +L + G +  S TASV +L   AI+R+I++ R   + R+  R + VV   
Sbjct: 111 PNTRRLTVSTWLLRQGLIDTSLTASVANLLAIAIERHITVFRMQLHTRMSNR-RVVVVIV 169

Query: 206 LMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYIL 265
           ++WT+AIV+  +P +GWNC      CS++ P   ++YL+FW     V  + +V  Y +I 
Sbjct: 170 VIWTMAIVMGAIPSVGWNCICDIENCSNMAPLYSDSYLVFWAIFNLVTFVVMVVLYAHIF 229

Query: 266 WKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGP 325
                  +RM +         H+S   + + T        + L KT+V++L   IICW P
Sbjct: 230 GYVRQRTMRMSR---------HSSGPRRNRDTM-------MSLLKTVVIVLGAFIICWTP 273

Query: 326 LLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGT 385
            L +++ DV      ++     F  +L   NS +NPIIY+ R K++   FR +   C+ +
Sbjct: 274 GLVLLLLDVCCPQCDVL-AYEKFFLLLAEFNSAMNPIIYSYRDKEMSATFRQIL-CCQRS 331

Query: 386 AQPLDNSMG 394
             P   + G
Sbjct: 332 ENPTGPTEG 340


>gi|13027636 sphingosine-1-phosphate receptor 1 [Homo sapiens]
          Length = 382

 Score =  130 bits (327), Expect = 2e-30
 Identities = 91/300 (30%), Positives = 155/300 (51%), Gaps = 21/300 (7%)

Query: 87  AVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHV 146
           +V+ + +  F +LEN+ VL  I  ++    RP Y+FIG+LA++DLL  V +  + +    
Sbjct: 49  SVVFILICCFIILENIFVLLTIWKTKKFH-RPMYYFIGNLALSDLLAGVAYTANLLLSGA 107

Query: 147 FHRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVT-RPKAVVAFC 205
              K +   +  + G +  + +ASV SL   AI+RYI++ +   +      R   +++ C
Sbjct: 108 TTYKLTPAQWFLREGSMFVALSASVFSLLAIAIERYITMLKMKLHNGSNNFRLFLLISAC 167

Query: 206 LMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYIL 265
             W I++++  LP++GWNC    S CS + P   + Y++F   V ++LLL IV  Y  I 
Sbjct: 168 --WVISLILGGLPIMGWNCISALSSCSTVLPLYHKHYILFCTTVFTLLLLSIVILYCRIY 225

Query: 266 WKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGP 325
               + + R+  R   K+I   +    K            + L KT++++L V I CW P
Sbjct: 226 SLVRTRSRRLTFR---KNISKASRSSEK-----------SLALLKTVIIVLSVFIACWAP 271

Query: 326 LLAIMVYDVFGKMNKLIKTVF--AFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCE 383
           L  +++ DV  K+ K    +F   +  +L +LNS  NPIIY L +K++R AF  +   C+
Sbjct: 272 LFILLLLDVGCKV-KTCDILFRAEYFLVLAVLNSGTNPIIYTLTNKEMRRAFIRIMSCCK 330


>gi|6912348 lysophosphatidic acid receptor 3 [Homo sapiens]
          Length = 353

 Score =  129 bits (325), Expect = 4e-30
 Identities = 80/297 (26%), Positives = 149/297 (50%), Gaps = 26/297 (8%)

Query: 88  VLSLTLGTFTVL----ENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFID 143
           V+ L +GTF  L     N LV+  ++ +R     P Y+ + +LA AD    + +V+   +
Sbjct: 31  VIVLCVGTFFCLFIFFSNSLVIAAVIKNRKFHF-PFYYLLANLAAADFFAGIAYVFLMFN 89

Query: 144 FHVFHRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVA 203
                +  + N +  + G + +S TAS+ +L + A++R++SI R   +  + T+ +  + 
Sbjct: 90  TGPVSKTLTVNRWFLRQGLLDSSLTASLTNLLVIAVERHMSIMRMRVHSNL-TKKRVTLL 148

Query: 204 FCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWI--GVTSVLLLFIVYAY 261
             L+W IAI +  +P LGWNC    S CS + P    +YL+FW    + + L++ +VY  
Sbjct: 149 ILLVWAIAIFMGAVPTLGWNCLCNISACSSLAPIYSRSYLVFWTVSNLMAFLIMVVVYLR 208

Query: 262 MYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLII 321
           +Y+  K             +K+ ++     G +      + R  ++L KT++ +L   ++
Sbjct: 209 IYVYVK-------------RKTNVLSPHTSGSI-----SRRRTPMKLMKTVMTVLGAFVV 250

Query: 322 CWGPLLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSM 378
           CW P L +++ D        ++ V  +  +L LLNS VNPIIY+ + +D+    + M
Sbjct: 251 CWTPGLVVLLLDGLNCRQCGVQHVKRWFLLLALLNSVVNPIIYSYKDEDMYGTMKKM 307


>gi|38788193 sphingosine-1-phosphate receptor 3 [Homo sapiens]
          Length = 378

 Score =  128 bits (322), Expect = 9e-30
 Identities = 98/346 (28%), Positives = 159/346 (45%), Gaps = 41/346 (11%)

Query: 88  VLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVF 147
           VL L + +F VLENL+VL  I  +     R  Y FIG+LA+ DLL  + +  + +     
Sbjct: 44  VLFLVICSFIVLENLMVLIAIWKNNKFHNR-MYFFIGNLALCDLLAGIAYKVNILMSGKK 102

Query: 148 HRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLM 207
               S  V+  + G +  +  AS  SL   AI+R++++ +   Y     R +  +   + 
Sbjct: 103 TFSLSPTVWFLREGSMFVALGASTCSLLAIAIERHLTMIKMRPYDAN-KRHRVFLLIGMC 161

Query: 208 WTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIV--YAYMYIL 265
           W IA  +  LP+LGWNC      CS I P   + Y+ F I + + +L+ IV  YA +Y L
Sbjct: 162 WLIAFTLGALPILGWNCLHNLPDCSTILPLYSKKYIAFCISIFTAILVTIVILYARIYFL 221

Query: 266 WKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGP 325
            K+ S                        +V   + +   + L +T+V+++ V I CW P
Sbjct: 222 VKSSSR-----------------------KVANHNNSERSMALLRTVVIVVSVFIACWSP 258

Query: 326 LLAIMVYDVFGKMNKL-IKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSC-- 382
           L  + + DV  ++    I     +  +L +LNS +NP+IY L SK++R AF  +  +C  
Sbjct: 259 LFILFLIDVACRVQACPILFKAQWFIVLAVLNSAMNPVIYTLASKEMRRAFFRLVCNCLV 318

Query: 383 ---EGTAQPLDNSMGDSDCLHKHANNAAS--------VHRAAESCI 417
                 A P+  ++  S      +NN++          H A  SCI
Sbjct: 319 RGRGARASPIQPALDPSRSKSSSSNNSSHSPKVKEDLPHTAPSSCI 364


>gi|4503459 sphingosine-1-phosphate receptor 4 precursor [Homo
           sapiens]
          Length = 384

 Score =  119 bits (297), Expect = 7e-27
 Identities = 96/330 (29%), Positives = 159/330 (48%), Gaps = 34/330 (10%)

Query: 85  AIAVLSLTLGTFTVLENLLVLCVIL-HSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFID 143
           A+  LS+      VLENLLVL  I  H RS R    Y+ + ++ ++DLL    ++ + + 
Sbjct: 48  ALRGLSVAASCLVVLENLLVLAAITSHMRSRRW--VYYCLVNITLSDLLTGAAYLANVLL 105

Query: 144 FHVFHRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVA 203
                 + +   +  + G +  +  AS  SL  TA +R+ ++ RP+A        +    
Sbjct: 106 SGARTFRLAPAQWFLREGLLFTALAASTFSLLFTAGERFATMVRPVAESGATKTSRVYGF 165

Query: 204 FCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMY 263
             L W +A ++ +LPLLGWNC      CS + P   + Y++F + + + +L  I+  Y  
Sbjct: 166 IGLCWLLAALLGMLPLLGWNCLCAFDRCSSLLPLYSKRYILFCLVIFAGVLATIMGLYGA 225

Query: 264 ILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICW 323
           I         R++Q   QK+              RP   R   RL KT+++IL+  ++CW
Sbjct: 226 IF--------RLVQASGQKA-------------PRPAARRKARRLLKTVLMILLAFLVCW 264

Query: 324 GPLLAIMVYDVFGK---MNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFP 380
           GPL  +++ DVFG      + ++ +  +   L +LNS VNPIIY+ RS+++  A  S   
Sbjct: 265 GPLFGLLLADVFGSNLWAQEYLRGM-DWILALAVLNSAVNPIIYSFRSREVCRAVLSFL- 322

Query: 381 SCEGTAQPLDNSMGDSDCLHK--HANNAAS 408
            C G  +      G  DCL +   A++ AS
Sbjct: 323 -CCGCLRL--GMRGPGDCLARAVEAHSGAS 349


>gi|7305013 lysophosphatidic acid receptor 2 [Homo sapiens]
          Length = 351

 Score =  117 bits (292), Expect = 3e-26
 Identities = 81/299 (27%), Positives = 137/299 (45%), Gaps = 22/299 (7%)

Query: 82  QQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSF 141
           + + +  L LT+    +L NLLV+  I  +R    +P Y+ +G+LA ADL   V   Y F
Sbjct: 31  KDVVVVALGLTVSVLVLLTNLLVIAAIASNRRFH-QPIYYLLGNLAAADLFAGV--AYLF 87

Query: 142 IDFHVFHR--KDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPK 199
           + FH   R  + S   +  + G +  S TASV +L   A++R+ S+     + R+  R +
Sbjct: 88  LMFHTGPRTARLSLEGWFLRQGLLDTSLTASVATLLAIAVERHRSVMAVQLHSRL-PRGR 146

Query: 200 AVVAFCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVY 259
            V+    +W  A+ + +LP   W+C      CS + P +  +YL  W   + ++ L +V 
Sbjct: 147 VVMLIVGVWVAALGLGLLPAHSWHCLCALDRCSRMAPLLSRSYLAVWALSSLLVFLLMVA 206

Query: 260 AYMYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVL 319
            Y  I +       RM +         H S         P      + L KT+V+IL   
Sbjct: 207 VYTRIFFYVRRRVQRMAE---------HVS-------CHPRYRETTLSLVKTVVIILGAF 250

Query: 320 IICWGPLLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSM 378
           ++CW P   +++ D  G  +  +  V  +  +L   NS VN  +Y+ R  ++R  FR +
Sbjct: 251 VVCWTPGQVVLLLDGLGCESCNVLAVEKYFLLLAEANSLVNAAVYSCRDAEMRRTFRRL 309


>gi|13540517 endothelial differentiation, sphingolipid
           G-protein-coupled receptor, 8 [Homo sapiens]
          Length = 398

 Score =  116 bits (290), Expect = 5e-26
 Identities = 87/293 (29%), Positives = 144/293 (49%), Gaps = 17/293 (5%)

Query: 85  AIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDF 144
           A AV+ L +  F VLENL VL V+         P +  +GSL ++DLL    +  + +  
Sbjct: 38  ADAVVCLAVCAFIVLENLAVLLVLGRHPRFHA-PMFLLLGSLTLSDLLAGAAYAANILLS 96

Query: 145 HVFHRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAF 204
                K S  ++  + GGV  + TASV SL   A++R +++ R      + +R + +   
Sbjct: 97  GPLTLKLSPALWFAREGGVFVALTASVLSLLAIALERSLTMARR-GPAPVSSRGRTLAMA 155

Query: 205 CLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYI 264
              W +++++ +LP LGWNC      CS + P   + Y++F +     +L  I   Y  I
Sbjct: 156 AAAWGVSLLLGLLPALGWNCLGRLDACSTVLPLYAKAYVLFCVLAFVGILAAICALYARI 215

Query: 265 LWKAHSHAVRMIQR-GTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICW 323
             +  ++A R+  R GT  +    TS       TR  +    + L +TL ++L+  + CW
Sbjct: 216 YCQVRANARRLPARPGTAGT----TS-------TRARRKPRSLALLRTLSVVLLAFVACW 264

Query: 324 GPLLAIMVYDVF--GKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHA 374
           GPL  +++ DV    +   ++     F   L + NS +NPIIY L ++DLRHA
Sbjct: 265 GPLFLLLLLDVACPARTCPVLLQADPFLG-LAMANSLLNPIIYTLTNRDLRHA 316


>gi|4885295 G protein-coupled receptor 12 [Homo sapiens]
          Length = 334

 Score =  115 bits (287), Expect = 1e-25
 Identities = 82/304 (26%), Positives = 146/304 (48%), Gaps = 39/304 (12%)

Query: 76  MVLNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSV 135
           +V+NP       ++  T GT    EN +V+ +I H+ SLR  P +  IGSLA+ADLL  +
Sbjct: 42  LVVNPWD-----IVLCTSGTLISCENAIVVLIIFHNPSLRA-PMFLLIGSLALADLLAGI 95

Query: 136 IFVYSFIDFHVFHRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIV 195
             + +F+  ++   + ++   L  +G + ASF+ASV SL    +DRY+S++  L Y    
Sbjct: 96  GLITNFVFAYLLQSEATK---LVTIGLIVASFSASVCSLLAITVDRYLSLYYALTYHSER 152

Query: 196 TRPKAVVAFCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLL 255
           T     V   ++W  +I + +LP++GWNC + +S CS + P       +  +   S L +
Sbjct: 153 TVTFTYVMLVMLWGTSICLGLLPVMGWNCLRDESTCSVVRPLTKNNAAILSV---SFLFM 209

Query: 256 FIVYAYMYI----LWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKT 311
           F +   +YI    +   H+H + +       S  + T +                    T
Sbjct: 210 FALMLQLYIQICKIVMRHAHQIALQHHFLATSHYVTTRKG-----------------VST 252

Query: 312 LVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSML-CLLNSTVNPIIYALRSKD 370
           L +IL     CW P     +Y +    +    +++ + ++L    NS +NP+IYA R+++
Sbjct: 253 LAIILGTFAACWMP---FTLYSLIA--DYTYPSIYTYATLLPATYNSIINPVIYAFRNQE 307

Query: 371 LRHA 374
           ++ A
Sbjct: 308 IQKA 311


>gi|4885325 G protein-coupled receptor 3 [Homo sapiens]
          Length = 330

 Score =  108 bits (270), Expect = 1e-23
 Identities = 87/311 (27%), Positives = 148/311 (47%), Gaps = 29/311 (9%)

Query: 80  PSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVY 139
           PS +    VL ++ GT    EN LV+ +I+ + + R  P +  +GSLAVADLL  +  V 
Sbjct: 38  PSPKAWDVVLCIS-GTLVSCENALVVAIIVGTPAFRA-PMFLLVGSLAVADLLAGLGLVL 95

Query: 140 SFIDFHVFHRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPK 199
            F          S  + L  +G +  +FTAS+GSL    +DRY+S++  L Y    T  +
Sbjct: 96  HFAAVFCI---GSAEMSLVLVGVLAMAFTASIGSLLAITVDRYLSLYNALTYYSETTVTR 152

Query: 200 AVVAFCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVY 259
             V   L+W  A+ + +LP+L WNC    + C  ++P + + +L     V   +  F+V+
Sbjct: 153 TYVMLALVWGGALGLGLLPVLAWNCLDGLTTCGVVYP-LSKNHL-----VVLAIAFFMVF 206

Query: 260 AYMYILWKAHSHAVRMIQRGTQK-SIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVV 318
               I+ + ++   R++ R  Q+ ++  H         TR   A        TL ++L  
Sbjct: 207 G---IMLQLYAQICRIVCRHAQQIALQRHLLPASHYVATRKGIA--------TLAVVLGA 255

Query: 319 LIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSML-CLLNSTVNPIIYALRSKDLRHAFRS 377
              CW   L   VY + G  +     ++ + ++L    NS +NPIIYA R++D++    +
Sbjct: 256 FAACW---LPFTVYCLLGDAHS--PPLYTYLTLLPATYNSMINPIIYAFRNQDVQKVLWA 310

Query: 378 MFPSCEGTAQP 388
           +   C  +  P
Sbjct: 311 VCCCCSSSKIP 321


>gi|111118990 alpha-1A-adrenergic receptor isoform 4 [Homo sapiens]
          Length = 455

 Score =  104 bits (259), Expect = 2e-22
 Identities = 90/329 (27%), Positives = 151/329 (45%), Gaps = 37/329 (11%)

Query: 78  LNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLL-GSVI 136
           +N S+ + + V+   L  F VL N+LV+  +   R L     Y+ + +LAVADLL  S +
Sbjct: 21  VNISKAILLGVILGGLILFGVLGNILVILSVACHRHLHSVTHYYIV-NLAVADLLLTSTV 79

Query: 137 FVYSFIDFHVFHRKDSRNVFLFKLGGVTA-SFTASVGSLFLTAIDRYISIHRPLAYKRIV 195
             +S I F V        VF      V     TAS+  L + +IDRYI +  PL Y  IV
Sbjct: 80  LPFSAI-FEVLGYWAFGRVFCNIWAAVDVLCCTASIMGLCIISIDRYIGVSYPLRYPTIV 138

Query: 196 TRPKAVVAFCLMWTIAIVIAVLPLLGWN---------CEKLQSVCSDIFPHIDETYLMFW 246
           T+ + ++A   +W +++VI++ PL GW          C+  +     +F  +   YL   
Sbjct: 139 TQRRGLMALLCVWALSLVISIGPLFGWRQPAPEDETICQINEEPGYVLFSALGSFYL--- 195

Query: 247 IGVTSVLLLFIVYAYMYILWKAHSHAVRMIQR-----GTQKSIIIHTSE---DGKVQVTR 298
                + ++ ++Y  +Y++ K  S  ++   +       Q ++ IH       G    + 
Sbjct: 196 ----PLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRKNAPAGGSGMASA 251

Query: 299 PDQARMDIRL---------AKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFC 349
             +    +RL         AKTL +++   ++CW P   +M    F    K  +TVF   
Sbjct: 252 KTKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFKPSETVFKIV 311

Query: 350 SMLCLLNSTVNPIIYALRSKDLRHAFRSM 378
             L  LNS +NPIIY   S++ + AF+++
Sbjct: 312 FWLGYLNSCINPIIYPCSSQEFKKAFQNV 340


>gi|111118992 alpha-1A-adrenergic receptor isoform 1 [Homo sapiens]
          Length = 466

 Score =  104 bits (259), Expect = 2e-22
 Identities = 90/329 (27%), Positives = 151/329 (45%), Gaps = 37/329 (11%)

Query: 78  LNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLL-GSVI 136
           +N S+ + + V+   L  F VL N+LV+  +   R L     Y+ + +LAVADLL  S +
Sbjct: 21  VNISKAILLGVILGGLILFGVLGNILVILSVACHRHLHSVTHYYIV-NLAVADLLLTSTV 79

Query: 137 FVYSFIDFHVFHRKDSRNVFLFKLGGVTA-SFTASVGSLFLTAIDRYISIHRPLAYKRIV 195
             +S I F V        VF      V     TAS+  L + +IDRYI +  PL Y  IV
Sbjct: 80  LPFSAI-FEVLGYWAFGRVFCNIWAAVDVLCCTASIMGLCIISIDRYIGVSYPLRYPTIV 138

Query: 196 TRPKAVVAFCLMWTIAIVIAVLPLLGWN---------CEKLQSVCSDIFPHIDETYLMFW 246
           T+ + ++A   +W +++VI++ PL GW          C+  +     +F  +   YL   
Sbjct: 139 TQRRGLMALLCVWALSLVISIGPLFGWRQPAPEDETICQINEEPGYVLFSALGSFYL--- 195

Query: 247 IGVTSVLLLFIVYAYMYILWKAHSHAVRMIQR-----GTQKSIIIHTSE---DGKVQVTR 298
                + ++ ++Y  +Y++ K  S  ++   +       Q ++ IH       G    + 
Sbjct: 196 ----PLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRKNAPAGGSGMASA 251

Query: 299 PDQARMDIRL---------AKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFC 349
             +    +RL         AKTL +++   ++CW P   +M    F    K  +TVF   
Sbjct: 252 KTKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFKPSETVFKIV 311

Query: 350 SMLCLLNSTVNPIIYALRSKDLRHAFRSM 378
             L  LNS +NPIIY   S++ + AF+++
Sbjct: 312 FWLGYLNSCINPIIYPCSSQEFKKAFQNV 340


>gi|111118986 alpha-1A-adrenergic receptor isoform 2 [Homo sapiens]
          Length = 475

 Score =  104 bits (259), Expect = 2e-22
 Identities = 90/329 (27%), Positives = 151/329 (45%), Gaps = 37/329 (11%)

Query: 78  LNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLL-GSVI 136
           +N S+ + + V+   L  F VL N+LV+  +   R L     Y+ + +LAVADLL  S +
Sbjct: 21  VNISKAILLGVILGGLILFGVLGNILVILSVACHRHLHSVTHYYIV-NLAVADLLLTSTV 79

Query: 137 FVYSFIDFHVFHRKDSRNVFLFKLGGVTA-SFTASVGSLFLTAIDRYISIHRPLAYKRIV 195
             +S I F V        VF      V     TAS+  L + +IDRYI +  PL Y  IV
Sbjct: 80  LPFSAI-FEVLGYWAFGRVFCNIWAAVDVLCCTASIMGLCIISIDRYIGVSYPLRYPTIV 138

Query: 196 TRPKAVVAFCLMWTIAIVIAVLPLLGWN---------CEKLQSVCSDIFPHIDETYLMFW 246
           T+ + ++A   +W +++VI++ PL GW          C+  +     +F  +   YL   
Sbjct: 139 TQRRGLMALLCVWALSLVISIGPLFGWRQPAPEDETICQINEEPGYVLFSALGSFYL--- 195

Query: 247 IGVTSVLLLFIVYAYMYILWKAHSHAVRMIQR-----GTQKSIIIHTSE---DGKVQVTR 298
                + ++ ++Y  +Y++ K  S  ++   +       Q ++ IH       G    + 
Sbjct: 196 ----PLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRKNAPAGGSGMASA 251

Query: 299 PDQARMDIRL---------AKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFC 349
             +    +RL         AKTL +++   ++CW P   +M    F    K  +TVF   
Sbjct: 252 KTKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFKPSETVFKIV 311

Query: 350 SMLCLLNSTVNPIIYALRSKDLRHAFRSM 378
             L  LNS +NPIIY   S++ + AF+++
Sbjct: 312 FWLGYLNSCINPIIYPCSSQEFKKAFQNV 340


>gi|111118988 alpha-1A-adrenergic receptor isoform 3 [Homo sapiens]
          Length = 429

 Score =  104 bits (259), Expect = 2e-22
 Identities = 90/329 (27%), Positives = 151/329 (45%), Gaps = 37/329 (11%)

Query: 78  LNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLL-GSVI 136
           +N S+ + + V+   L  F VL N+LV+  +   R L     Y+ + +LAVADLL  S +
Sbjct: 21  VNISKAILLGVILGGLILFGVLGNILVILSVACHRHLHSVTHYYIV-NLAVADLLLTSTV 79

Query: 137 FVYSFIDFHVFHRKDSRNVFLFKLGGVTA-SFTASVGSLFLTAIDRYISIHRPLAYKRIV 195
             +S I F V        VF      V     TAS+  L + +IDRYI +  PL Y  IV
Sbjct: 80  LPFSAI-FEVLGYWAFGRVFCNIWAAVDVLCCTASIMGLCIISIDRYIGVSYPLRYPTIV 138

Query: 196 TRPKAVVAFCLMWTIAIVIAVLPLLGWN---------CEKLQSVCSDIFPHIDETYLMFW 246
           T+ + ++A   +W +++VI++ PL GW          C+  +     +F  +   YL   
Sbjct: 139 TQRRGLMALLCVWALSLVISIGPLFGWRQPAPEDETICQINEEPGYVLFSALGSFYL--- 195

Query: 247 IGVTSVLLLFIVYAYMYILWKAHSHAVRMIQR-----GTQKSIIIHTSE---DGKVQVTR 298
                + ++ ++Y  +Y++ K  S  ++   +       Q ++ IH       G    + 
Sbjct: 196 ----PLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRKNAPAGGSGMASA 251

Query: 299 PDQARMDIRL---------AKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFC 349
             +    +RL         AKTL +++   ++CW P   +M    F    K  +TVF   
Sbjct: 252 KTKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFKPSETVFKIV 311

Query: 350 SMLCLLNSTVNPIIYALRSKDLRHAFRSM 378
             L  LNS +NPIIY   S++ + AF+++
Sbjct: 312 FWLGYLNSCINPIIYPCSSQEFKKAFQNV 340


>gi|134244587 endothelial differentiation, sphingolipid
           G-protein-coupled receptor, 5 [Homo sapiens]
          Length = 353

 Score =  103 bits (257), Expect = 3e-22
 Identities = 84/295 (28%), Positives = 139/295 (47%), Gaps = 33/295 (11%)

Query: 81  SQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYS 140
           S+Q+A A + + L    V+ENLLVL  +  +        Y F+G+LA +DLL  V FV +
Sbjct: 32  SRQVASAFIVI-LCCAIVVENLLVLIAVARNSKFHSA-MYLFLGNLAASDLLAGVAFVAN 89

Query: 141 FIDFHVFHRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKA 200
            +       + +   +  + G    + +ASV SL   AI+R+++I +   Y    +  + 
Sbjct: 90  TLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSC-RM 148

Query: 201 VVAFCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYA 260
           ++     W I++V+  LP+LGWNC      CS + P   + Y++  + + S++LL IV  
Sbjct: 149 LLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVAL 208

Query: 261 YMYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLI 320
           Y+ I     S    M                          A   + L KT+ ++L V I
Sbjct: 209 YVRIYCVVRSSHADM-------------------------AAPQTLALLKTVTIVLGVFI 243

Query: 321 ICWGPLLAIMVYDVFGKMNK---LIKTVFAFCSMLCLLNSTVNPIIYALRSKDLR 372
           +CW P  +I++ D    ++    L K  + F   +  LNS +NP+IY  RS+DLR
Sbjct: 244 VCWLPAFSILLLDYACPVHSCPILYKAHYFFA--VSTLNSLLNPVIYTWRSRDLR 296


>gi|4885341 G protein-coupled receptor 6 [Homo sapiens]
          Length = 362

 Score =  103 bits (257), Expect = 3e-22
 Identities = 84/300 (28%), Positives = 138/300 (46%), Gaps = 34/300 (11%)

Query: 88  VLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVF 147
           VL    GT    EN LV+ +I  + +LR  P +  +GSLA ADLL     +  F+  ++ 
Sbjct: 77  VLLCVSGTVIAGENALVVALIASTPALRT-PMFVLVGSLATADLLAGCGLILHFVFQYLV 135

Query: 148 HRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLM 207
               S  V L  +G + ASF ASV SL    +DRY+S++  L Y    T     +     
Sbjct: 136 ---PSETVSLLTVGFLVASFAASVSSLLAITVDRYLSLYNALTYYSRRTLLGVHLLLAAT 192

Query: 208 WTIAIVIAVLPLLGWNCEKLQSVCSDIFP----HIDETYLMFWIGVTSVLLLFIVYAYMY 263
           WT+++ + +LP+LGWNC   ++ CS + P    H+      F++    +L L++      
Sbjct: 193 WTVSLGLGLLPVLGWNCLAERAACSVVRPLARSHVALLSAAFFMVFGIMLHLYV--RICQ 250

Query: 264 ILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICW 323
           ++W+ H+H + + Q         H      +  TR        +   TL ++L      W
Sbjct: 251 VVWR-HAHQIALQQ---------HCLAPPHLAATR--------KGVGTLAVVLGTFGASW 292

Query: 324 GPLLAIMVYDVFGKMNKLIKTVFAFCSML-CLLNSTVNPIIYALRSKDLRHAFRSMFPSC 382
              L   +Y V G        V+ + ++L    NS +NPIIYA R+++++ A   +   C
Sbjct: 293 ---LPFAIYCVVGSHED--PAVYTYATLLPATYNSMINPIIYAFRNQEIQRALWLLLCGC 347


>gi|4505127 melanocortin 2 receptor [Homo sapiens]
          Length = 297

 Score =  100 bits (248), Expect = 3e-21
 Identities = 84/305 (27%), Positives = 133/305 (43%), Gaps = 65/305 (21%)

Query: 92  TLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVFHRKD 151
           T+    VLENL+VL  +  +++L+  P Y FI SLA++D+LGS+  +   I   +     
Sbjct: 33  TISIVGVLENLIVLLAVFKNKNLQA-PMYFFICSLAISDMLGSLYKILENILIIL----- 86

Query: 152 SRNVFLFKLGG-------------VTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRP 198
            RN+   K  G                S   S+ SL + A DRYI+I   L Y  IVT  
Sbjct: 87  -RNMGYLKPRGSFETTADDIIDSLFVLSLLGSIFSLSVIAADRYITIFHALRYHSIVTMR 145

Query: 199 KAVVAFCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFI- 257
           + VV   ++WT      +  +              IF H   T + F   +  ++L+FI 
Sbjct: 146 RTVVVLTVIWTFCTGTGITMV--------------IFSHHVPTVITF-TSLFPLMLVFIL 190

Query: 258 -VYAYMYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLIL 316
            +Y +M++L ++H+  +  + R   K  I                         TL ++L
Sbjct: 191 CLYVHMFLLARSHTRKISTLPRANMKGAI-------------------------TLTILL 225

Query: 317 VVLIICWGPLLAIMVYDVFGKMN---KLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRH 373
            V I CW P +  ++   F   N       ++F    ML + N+ ++P IYA RS +LR 
Sbjct: 226 GVFIFCWAPFVLHVLLMTFCPSNPYCACYMSLFQVNGMLIMCNAVIDPFIYAFRSPELRD 285

Query: 374 AFRSM 378
           AF+ M
Sbjct: 286 AFKKM 290


>gi|4501959 alpha-1B-adrenergic receptor [Homo sapiens]
          Length = 520

 Score = 96.7 bits (239), Expect = 4e-20
 Identities = 94/327 (28%), Positives = 151/327 (46%), Gaps = 36/327 (11%)

Query: 89  LSLTLGTF---TVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFH 145
           + L LG F    ++ N+LV+  +  +R LR  P+ +FI +LA+ADLL S   +       
Sbjct: 48  VGLVLGAFILFAIVGNILVILSVACNRHLRT-PTNYFIVNLAMADLLLSFTVLPFSAALE 106

Query: 146 VFHRKDSRNVFLFKLGGVTA-SFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAF 204
           V        +F      V     TAS+ SL   +IDRYI +   L Y  +VTR KA++A 
Sbjct: 107 VLGYWVLGRIFCDIWAAVDVLCCTASILSLCAISIDRYIGVRYSLQYPTLVTRRKAILAL 166

Query: 205 CLMWTIAIVIAVLPLLGW-----NCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVY 259
             +W ++ VI++ PLLGW     N +K   V  + F  +  +   F+I +  +L   ++Y
Sbjct: 167 LSVWVLSTVISIGPLLGWKEPAPNDDKECGVTEEPFYALFSSLGSFYIPLAVIL---VMY 223

Query: 260 AYMYI------------LWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQA----- 302
             +YI            + K  S++  +  R   K+    T    K +   P  +     
Sbjct: 224 CRVYIVAKRTTKNLEAGVMKEMSNSKELTLRIHSKNFHEDTLSSTKAKGHNPRSSIAVKL 283

Query: 303 ---RMDIRLAKTLVLILVVLIICWGP-LLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNST 358
                + + AKTL +++ + I+CW P  +A+ +  +F  + K    VF     L   NS 
Sbjct: 284 FKFSREKKAAKTLGIVVGMFILCWLPFFIALPLGSLFSTL-KPPDAVFKVVFWLGYFNSC 342

Query: 359 VNPIIYALRSKDLRHAF-RSMFPSCEG 384
           +NPIIY   SK+ + AF R +   C G
Sbjct: 343 LNPIIYPCSSKEFKRAFVRILGCQCRG 369


>gi|5174535 melanocortin 5 receptor [Homo sapiens]
          Length = 325

 Score = 95.5 bits (236), Expect = 8e-20
 Identities = 82/318 (25%), Positives = 143/318 (44%), Gaps = 46/318 (14%)

Query: 79  NPSQQLAIAV-LSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIF 137
           +P + + IAV + LTLG  ++LEN+LV+  I+ +++L   P Y F+ SLAVAD+L S+  
Sbjct: 31  SPCEDMGIAVEVFLTLGVISLLENILVIGAIVKNKNLHS-PMYFFVCSLAVADMLVSMSS 89

Query: 138 VYSFIDFHVFHRKDS--RNVFLFKLGGV-----TASFTASVGSLFLTAIDRYISIHRPLA 190
            +  I  ++ + K     + F+  +  V       S  AS+ SL   A+DRY++I   L 
Sbjct: 90  AWETITIYLLNNKHLVIADAFVRHIDNVFDSMICISVVASMCSLLAIAVDRYVTIFYALR 149

Query: 191 YKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETY-LMFWIGV 249
           Y  I+T  ++      +W       ++ +L                + + TY ++  I +
Sbjct: 150 YHHIMTARRSGAIIAGIWAFCTGCGIVFIL----------------YSESTYVILCLISM 193

Query: 250 TSVLLLFIVYAYMYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLA 309
              +L  +V  Y+++   A +H  R+       S    TS  G V VT            
Sbjct: 194 FFAMLFLLVSLYIHMFLLARTHVKRIAALPGASSARQRTSMQGAVTVT------------ 241

Query: 310 KTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSM---LCLLNSTVNPIIYAL 366
               ++L V  +CW P    +   +    N       +  +M   L + NS ++P+IYA 
Sbjct: 242 ----MLLGVFTVCWAPFFLHLTLMLSCPQNLYCSRFMSHFNMYLILIMCNSVMDPLIYAF 297

Query: 367 RSKDLRHAFRSMFPSCEG 384
           RS+++R  F+ +   C G
Sbjct: 298 RSQEMRKTFKEII-CCRG 314


>gi|119508433 melanocortin 4 receptor [Homo sapiens]
          Length = 332

 Score = 93.6 bits (231), Expect = 3e-19
 Identities = 82/322 (25%), Positives = 146/322 (45%), Gaps = 46/322 (14%)

Query: 66  GENFMDIECFMVLNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGS 125
           G+ + D  C+  L  S ++ +     TLG  ++LEN+LV+  I  +++L   P Y FI S
Sbjct: 32  GKGYSDGGCYEQLFVSPEVFV-----TLGVISLLENILVIVAIAKNKNLHS-PMYFFICS 85

Query: 126 LAVADLLGSVIFVYSFIDFHVFHRKDS-RNVFLFKLGGVT-----ASFTASVGSLFLTAI 179
           LAVAD+L SV      I   + +  D+    F   +  V      +S  AS+ SL   A+
Sbjct: 86  LAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAV 145

Query: 180 DRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHID 239
           DRY +I   L Y  I+T  +  +    +W    V  +L +          + SD    I 
Sbjct: 146 DRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFI----------IYSDSSAVII 195

Query: 240 ETYLMFWIGVTSVLLLFIVYAYMYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRP 299
               MF+   T + L+  +Y +M+++ + H   + ++                    T  
Sbjct: 196 CLITMFF---TMLALMASLYVHMFLMARLHIKRIAVLPG------------------TGA 234

Query: 300 DQARMDIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKMNK---LIKTVFAFCSMLCLLN 356
            +   +++ A TL +++ V ++CW P    +++ +    N       + F    +L + N
Sbjct: 235 IRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCN 294

Query: 357 STVNPIIYALRSKDLRHAFRSM 378
           S ++P+IYALRS++LR  F+ +
Sbjct: 295 SIIDPLIYALRSQELRKTFKEI 316


>gi|170671732 melanocortin 3 receptor [Homo sapiens]
          Length = 323

 Score = 93.6 bits (231), Expect = 3e-19
 Identities = 80/304 (26%), Positives = 136/304 (44%), Gaps = 40/304 (13%)

Query: 91  LTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVFHRK 150
           L+LG  ++LEN+LV+  ++ + +L   P Y F+ SLAVAD+L SV      I   + H  
Sbjct: 46  LSLGIVSLLENILVILAVVRNGNLHS-PMYFFLCSLAVADMLVSVSNALETIMIAIVHSD 104

Query: 151 --DSRNVFLFKLGGV-----TASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVA 203
                + F+  +  +       S  AS+ +L   A+DRY++I   L Y  I+T  KA+  
Sbjct: 105 YLTFEDQFIQHMDNIFDSMICISLVASICNLLAIAVDRYVTIFYALRYHSIMTVRKALTL 164

Query: 204 FCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMY 263
              +W    V  V+ ++ ++  K+  VC            MF+     +LL+  +Y +M+
Sbjct: 165 IVAIWVCCGVCGVVFIV-YSESKMVIVC---------LITMFF---AMMLLMGTLYVHMF 211

Query: 264 ILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICW 323
           +  + H   +  +      +   H+   G V +T                ++L V I CW
Sbjct: 212 LFARLHVKRIAALPPADGVAPQQHSCMKGAVTIT----------------ILLGVFIFCW 255

Query: 324 GPLLAIMVYDVFGKMNKLIKTVFAFCS---MLCLLNSTVNPIIYALRSKDLRHAFRSMFP 380
            P    +V  +    N       A  +   +L + NS ++P+IYA RS +LR+ FR +  
Sbjct: 256 APFFLHLVLIITCPTNPYCICYTAHFNTYLVLIMCNSVIDPLIYAFRSLELRNTFREILC 315

Query: 381 SCEG 384
            C G
Sbjct: 316 GCNG 319


>gi|4501951 adenosine A2b receptor [Homo sapiens]
          Length = 332

 Score = 93.6 bits (231), Expect = 3e-19
 Identities = 87/325 (26%), Positives = 144/325 (44%), Gaps = 43/325 (13%)

Query: 76  MVLNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSV 135
           M+L     L +A L L +   +V  N+LV   +  + +L+  P+ +F+ SLA AD+   +
Sbjct: 1   MLLETQDALYVA-LELVIAALSVAGNVLVCAAVGTANTLQT-PTNYFLVSLAAADVAVGL 58

Query: 136 IFVYSFIDFHVFHRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIV 195
             +   I   +    D     LF    V     +S+ SL   A+DRY++I  PL YK +V
Sbjct: 59  FAIPFAITISLGFCTDFYGC-LFLACFVLVLTQSSIFSLLAVAVDRYLAICVPLRYKSLV 117

Query: 196 TRPKAVVAFCLMWTIAIVIAVLPLLGWN--------------------CEKLQSVCSDIF 235
           T  +A     ++W +A  I + P LGWN                    C  ++ +  ++ 
Sbjct: 118 TGTRARGVIAVLWVLAFGIGLTPFLGWNSKDSATNNCTEPWDGTTNESCCLVKCLFENVV 177

Query: 236 PHIDETYLMFWIGVTSVLLLFIVYAYMYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQ 295
           P     Y  F+  V   LL+ +V   +YI  K    A R +QR     ++ H+       
Sbjct: 178 PMSYMVYFNFFGCVLPPLLIMLV---IYI--KIFLVACRQLQR---TELMDHSR------ 223

Query: 296 VTRPDQARMDIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFA--FCSMLC 353
                  + +I  AK+L +I+ +  +CW P+ A+    +F       K  +A     +L 
Sbjct: 224 ----TTLQREIHAAKSLAMIVGIFALCWLPVHAVNCVTLFQPAQGKNKPKWAMNMAILLS 279

Query: 354 LLNSTVNPIIYALRSKDLRHAFRSM 378
             NS VNPI+YA R++D R+ F  +
Sbjct: 280 HANSVVNPIVYAYRNRDFRYTFHKI 304


>gi|4501957 alpha-1D-adrenergic receptor [Homo sapiens]
          Length = 572

 Score = 93.6 bits (231), Expect = 3e-19
 Identities = 82/328 (25%), Positives = 140/328 (42%), Gaps = 41/328 (12%)

Query: 81  SQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYS 140
           +Q + + V         V  NLLV+  +  +R L+   +Y FI +LAVADLL S   +  
Sbjct: 94  AQGVGVGVFLAAFILMAVAGNLLVILSVACNRHLQTVTNY-FIVNLAVADLLLSATVLPF 152

Query: 141 FIDFHVFHRKDSRNVFLFKLGGVTA-SFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPK 199
                V         F      V     TAS+ SL   ++DRY+ +   L Y  I+T  K
Sbjct: 153 SATMEVLGFWAFGRAFCDVWAAVDVLCCTASILSLCTISVDRYVGVRHSLKYPAIMTERK 212

Query: 200 AVVAFCLMWTIAIVIAVLPLLGWN---------CEKLQSVCSDIFPHIDETYLMFWIGVT 250
           A     L+W +A+V++V PLLGW          C   +     +F  +   YL       
Sbjct: 213 AAAILALLWVVALVVSVGPLLGWKEPVPPDERFCGITEEAGYAVFSSVCSFYL------- 265

Query: 251 SVLLLFIVYAYMYILWKAHSHAVR---MIQRGTQKSIIIH-------TSEDG----KVQV 296
            + ++ ++Y  +Y++ ++ + ++      +RG    +++        T  DG    +   
Sbjct: 266 PMAVIVVMYCRVYVVARSTTRSLEAGVKRERGKASEVVLRIHCRGAATGADGAHGMRSAK 325

Query: 297 TRPDQARMDIRL---------AKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFA 347
               ++ + +RL         AKTL +++ V ++CW P   ++         K  + VF 
Sbjct: 326 GHTFRSSLSVRLLKFSREKKAAKTLAIVVGVFVLCWFPFFFVLPLGSLFPQLKPSEGVFK 385

Query: 348 FCSMLCLLNSTVNPIIYALRSKDLRHAF 375
               L   NS VNP+IY   S++ + AF
Sbjct: 386 VIFWLGYFNSCVNPLIYPCSSREFKRAF 413


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.327    0.138    0.414 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,305,166
Number of Sequences: 37866
Number of extensions: 561267
Number of successful extensions: 3398
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 269
Number of HSP's successfully gapped in prelim test: 395
Number of HSP's that attempted gapping in prelim test: 2299
Number of HSP's gapped (non-prelim): 1035
length of query: 439
length of database: 18,247,518
effective HSP length: 105
effective length of query: 334
effective length of database: 14,271,588
effective search space: 4766710392
effective search space used: 4766710392
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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