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Search of human proteins with 11559923
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|11559923 eukaryotic translation initiation factor 4H isoform
1 [Homo sapiens]
(248 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|11559923 eukaryotic translation initiation factor 4H isoform ... 512 e-145
gi|14702180 eukaryotic translation initiation factor 4H isoform ... 457 e-129
gi|50053795 eukaryotic translation initiation factor 4B [Homo sa... 97 2e-20
gi|55956788 nucleolin [Homo sapiens] 65 4e-11
gi|4502847 cold inducible RNA binding protein [Homo sapiens] 64 2e-10
gi|4826734 fusion (involved in t(12;16) in malignant liposarcoma... 62 4e-10
gi|238859597 RNA binding motif protein 34 isoform 1 [Homo sapiens] 53 3e-07
gi|19923387 nuclear cap binding protein subunit 2, 20kDa isoform... 53 3e-07
gi|253970504 Ewing sarcoma breakpoint region 1 isoform 4 [Homo s... 52 4e-07
gi|4885225 Ewing sarcoma breakpoint region 1 isoform 2 [Homo sap... 52 4e-07
gi|4507353 TBP-associated factor 15 isoform 2 [Homo sapiens] 51 1e-06
gi|21327701 TBP-associated factor 15 isoform 1 [Homo sapiens] 51 1e-06
gi|56699409 RNA binding motif protein, X-linked [Homo sapiens] 51 1e-06
gi|118600973 RNA binding motif protein, X-linked 2 [Homo sapiens] 50 2e-06
gi|14110407 heterogeneous nuclear ribonucleoprotein D-like [Homo... 49 5e-06
gi|4759098 splicing factor, arginine/serine-rich 10 [Homo sapiens] 49 5e-06
gi|9558733 transformer-2 alpha [Homo sapiens] 48 7e-06
gi|153252068 testes-specific heterogenous nuclear ribonucleoprot... 47 1e-05
gi|5803137 RNA binding motif protein 3 [Homo sapiens] 47 1e-05
gi|14149675 cleavage stimulation factor, 3' pre-RNA, subunit 2, ... 47 1e-05
gi|14110420 heterogeneous nuclear ribonucleoprotein D isoform a ... 47 2e-05
gi|14110417 heterogeneous nuclear ribonucleoprotein D isoform b ... 47 2e-05
gi|253970502 Ewing sarcoma breakpoint region 1 isoform 3 [Homo s... 46 3e-05
gi|253970500 Ewing sarcoma breakpoint region 1 isoform 1 [Homo s... 46 3e-05
gi|4557493 cleavage stimulation factor subunit 2 [Homo sapiens] 46 3e-05
gi|242117971 RNA binding motif protein, X-linked-like 1 [Homo sa... 46 3e-05
gi|21361809 RNA binding motif protein, X-linked-like 1 [Homo sap... 46 3e-05
gi|29568103 U1 small nuclear ribonucleoprotein 70 kDa [Homo sapi... 45 6e-05
gi|14043070 heterogeneous nuclear ribonucleoprotein A1 isoform b... 44 1e-04
gi|4504445 heterogeneous nuclear ribonucleoprotein A1 isoform a ... 44 1e-04
>gi|11559923 eukaryotic translation initiation factor 4H isoform 1
[Homo sapiens]
Length = 248
Score = 512 bits (1318), Expect = e-145
Identities = 248/248 (100%), Positives = 248/248 (100%)
Query: 1 MADFDTYDDRAYSSFGGGRGSRGSAGGHGSRSQKELPTEPPYTAYVGNLPFNTVQGDIDA 60
MADFDTYDDRAYSSFGGGRGSRGSAGGHGSRSQKELPTEPPYTAYVGNLPFNTVQGDIDA
Sbjct: 1 MADFDTYDDRAYSSFGGGRGSRGSAGGHGSRSQKELPTEPPYTAYVGNLPFNTVQGDIDA 60
Query: 61 IFKDLSIRSVRLVRDKDTDKFKGFCYVEFDEVDSLKEALTYDGALLGDRSLRVDIAEGRK 120
IFKDLSIRSVRLVRDKDTDKFKGFCYVEFDEVDSLKEALTYDGALLGDRSLRVDIAEGRK
Sbjct: 61 IFKDLSIRSVRLVRDKDTDKFKGFCYVEFDEVDSLKEALTYDGALLGDRSLRVDIAEGRK 120
Query: 121 QDKGGFGFRKGGPDDRGMGSSRESRGGWDSRDDFNSGFRDDFLGGRGGSRPGDRRTGPPM 180
QDKGGFGFRKGGPDDRGMGSSRESRGGWDSRDDFNSGFRDDFLGGRGGSRPGDRRTGPPM
Sbjct: 121 QDKGGFGFRKGGPDDRGMGSSRESRGGWDSRDDFNSGFRDDFLGGRGGSRPGDRRTGPPM 180
Query: 181 GSRFRDGPPLRGSNMDFREPTEEERAQRPRLQLKPRTVATPLNQVANPNSAIFGGARPRE 240
GSRFRDGPPLRGSNMDFREPTEEERAQRPRLQLKPRTVATPLNQVANPNSAIFGGARPRE
Sbjct: 181 GSRFRDGPPLRGSNMDFREPTEEERAQRPRLQLKPRTVATPLNQVANPNSAIFGGARPRE 240
Query: 241 EVVQKEQE 248
EVVQKEQE
Sbjct: 241 EVVQKEQE 248
>gi|14702180 eukaryotic translation initiation factor 4H isoform 2
[Homo sapiens]
Length = 228
Score = 457 bits (1177), Expect = e-129
Identities = 228/248 (91%), Positives = 228/248 (91%), Gaps = 20/248 (8%)
Query: 1 MADFDTYDDRAYSSFGGGRGSRGSAGGHGSRSQKELPTEPPYTAYVGNLPFNTVQGDIDA 60
MADFDTYDDRAYSSFGGGRGSRGSAGGHGSRSQKELPTEPPYTAYVGNLPFNTVQGDIDA
Sbjct: 1 MADFDTYDDRAYSSFGGGRGSRGSAGGHGSRSQKELPTEPPYTAYVGNLPFNTVQGDIDA 60
Query: 61 IFKDLSIRSVRLVRDKDTDKFKGFCYVEFDEVDSLKEALTYDGALLGDRSLRVDIAEGRK 120
IFKDLSIRSVRLVRDKDTDKFKGFCYVEFDEVDSLKEALTYDGALLGDRSLRVDIAEGRK
Sbjct: 61 IFKDLSIRSVRLVRDKDTDKFKGFCYVEFDEVDSLKEALTYDGALLGDRSLRVDIAEGRK 120
Query: 121 QDKGGFGFRKGGPDDRGMGSSRESRGGWDSRDDFNSGFRDDFLGGRGGSRPGDRRTGPPM 180
QDKGGFGFRKGGPDDR GFRDDFLGGRGGSRPGDRRTGPPM
Sbjct: 121 QDKGGFGFRKGGPDDR--------------------GFRDDFLGGRGGSRPGDRRTGPPM 160
Query: 181 GSRFRDGPPLRGSNMDFREPTEEERAQRPRLQLKPRTVATPLNQVANPNSAIFGGARPRE 240
GSRFRDGPPLRGSNMDFREPTEEERAQRPRLQLKPRTVATPLNQVANPNSAIFGGARPRE
Sbjct: 161 GSRFRDGPPLRGSNMDFREPTEEERAQRPRLQLKPRTVATPLNQVANPNSAIFGGARPRE 220
Query: 241 EVVQKEQE 248
EVVQKEQE
Sbjct: 221 EVVQKEQE 228
>gi|50053795 eukaryotic translation initiation factor 4B [Homo
sapiens]
Length = 611
Score = 96.7 bits (239), Expect = 2e-20
Identities = 93/300 (31%), Positives = 134/300 (44%), Gaps = 85/300 (28%)
Query: 33 QKELPTEPPYTAYVGNLPFNTVQGDIDAIFKDLSIRSVRLVRD-KDTDKFKGFCYVEFDE 91
+ LP PPYTA++GNLP++ + I F+ L+I +VRL R+ + ++ KGF Y EF++
Sbjct: 87 RSRLPKSPPYTAFLGNLPYDVTEESIKEFFRGLNISAVRLPREPSNPERLKGFGYAEFED 146
Query: 92 VDSLKEALTYDGALLGDRSLRVDI---AEGRKQDKGGFGFRKGGPDD------------- 135
+DSL AL+ + LG+R +RVD+ A+ + +D FG + D
Sbjct: 147 LDSLLSALSLNEESLGNRRIRVDVADQAQDKDRDDRSFGRDRNRDSDKTDTDWRARPATD 206
Query: 136 --------RGMGSSRES-RGGWDS---RDDFNSGFRD------DFLGGRG-----GSRPG 172
RG S + R +DS RD + G+RD D GGR GSR
Sbjct: 207 SFDDYPPRRGDDSFGDKYRDRYDSDRYRDGYRDGYRDGPRRDMDRYGGRDRYDDRGSRDY 266
Query: 173 DR----RTGP---PMGSRFRDGPPLRG-----------------------SNMDFREPTE 202
DR R G GS +R RG S D+R +
Sbjct: 267 DRGYDSRIGSGRRAFGSGYRRDDDYRGGGDRYEDRYDRRDDRSWSSRDDYSRDDYRR-DD 325
Query: 203 EERAQRPRLQLKPRTVATPLNQVANPN-----SAIFGGARP---------REEVVQKEQE 248
QRP+L LKPR+ + A+ + ++IFGGA+P EE +QKEQE
Sbjct: 326 RGPPQRPKLNLKPRSTPKEDDSSASTSQSTRAASIFGGAKPVDTAAREREVEERLQKEQE 385
>gi|55956788 nucleolin [Homo sapiens]
Length = 710
Score = 65.5 bits (158), Expect = 4e-11
Identities = 53/159 (33%), Positives = 80/159 (50%), Gaps = 15/159 (9%)
Query: 29 GSRSQKELPTEPPYTAYVGNLPFNTVQGDIDAIFKDLSIRSVRLVRDKDTDKFKGFCYVE 88
G R ++P T +V L +T + + F D S+R+ R+V D++T KGF +V+
Sbjct: 559 GPRGSPNARSQPSKTLFVKGLSEDTTEETLKESF-DGSVRA-RIVTDRETGSSKGFGFVD 616
Query: 89 F---DEVDSLKEALTYDGALLGDRSLRVDIAEGRKQDKGGFGFRKGGPDD-RGMGSSRES 144
F ++ + KEA+ DG + G++ V + + + +GGFG R GG G G R
Sbjct: 617 FNSEEDAKAAKEAME-DGEIDGNK---VTLDWAKPKGEGGFGGRGGGRGGFGGRGGGRGG 672
Query: 145 RGGWDSRDDFNSGFRDDFLGGRGGSRPGDRRTGPPMGSR 183
RGG+ R G R F GGRGG GD + P G +
Sbjct: 673 RGGFGGRGRGGFGGRGGFRGGRGGG--GDHK---PQGKK 706
Score = 38.5 bits (88), Expect = 0.005
Identities = 24/96 (25%), Positives = 46/96 (47%), Gaps = 2/96 (2%)
Query: 30 SRSQKELPTEPP--YTAYVGNLPFNTVQGDIDAIFKDLSIRSVRLVRDKDTDKFKGFCYV 87
++ QK TEP + +VGNL FN ++ D+ ++ V D + F YV
Sbjct: 293 AKKQKVEGTEPTTAFNLFVGNLNFNKSAPELKTGISDVFAKNDLAVVDVRIGMTRKFGYV 352
Query: 88 EFDEVDSLKEALTYDGALLGDRSLRVDIAEGRKQDK 123
+F+ + L++AL G + ++++ +G+ K
Sbjct: 353 DFESAEDLEKALELTGLKVFGNEIKLEKPKGKDSKK 388
Score = 35.4 bits (80), Expect = 0.046
Identities = 35/117 (29%), Positives = 53/117 (45%), Gaps = 16/117 (13%)
Query: 29 GSRSQKELPTEPPYTAYVGNLPFNTVQGDIDAIFKDLSIRSVRLVRDKDTDKFKGFCYVE 88
G S+KE T NLP+ Q ++ +F+D + +RLV KD K KG Y+E
Sbjct: 383 GKDSKKERDAR---TLLAKNLPYKVTQDELKEVFEDAA--EIRLV-SKD-GKSKGIAYIE 435
Query: 89 F-DEVDSLKEALTYDGALLGDRSLRVDIA--EGRKQDKGGFGFRKGGPDDRGMGSSR 142
F E D+ K G + RS+ + +G+ QD +GG + G S+
Sbjct: 436 FKTEADAEKTFEEKQGTEIDGRSISLYYTGEKGQNQD------YRGGKNSTWSGESK 486
Score = 32.0 bits (71), Expect = 0.51
Identities = 33/145 (22%), Positives = 56/145 (38%), Gaps = 16/145 (11%)
Query: 43 TAYVGNLPFNTVQGDIDAIFKDLSIRSVRLVRDKDTDKFKGFCYVEFDEVDSLKEAL-TY 101
T + NL ++ + + +F+ + V K KG+ ++EF + KEAL +
Sbjct: 487 TLVLSNLSYSATEETLQEVFEKATFIKVP---QNQNGKSKGYAFIEFASFEDAKEALNSC 543
Query: 102 DGALLGDRSLRVDIAEGRKQDKGGFGFRKGGPDDRGMGSSRESRGGWDSRDDFNSGFRDD 161
+ + R++R+++ R G P+ R S G S D ++
Sbjct: 544 NKREIEGRAIRLELQGPR-----------GSPNARSQPSKTLFVKGL-SEDTTEETLKES 591
Query: 162 FLGGRGGSRPGDRRTGPPMGSRFRD 186
F G DR TG G F D
Sbjct: 592 FDGSVRARIVTDRETGSSKGFGFVD 616
>gi|4502847 cold inducible RNA binding protein [Homo sapiens]
Length = 172
Score = 63.5 bits (153), Expect = 2e-10
Identities = 42/132 (31%), Positives = 67/132 (50%), Gaps = 7/132 (5%)
Query: 45 YVGNLPFNTVQGDIDAIFKDLS-IRSVRLVRDKDTDKFKGFCYVEFDEVDSLKEA-LTYD 102
+VG L F+T + ++ +F I V +V+D++T + +GF +V F+ +D K+A + +
Sbjct: 9 FVGGLSFDTNEQSLEQVFSKYGQISEVVVVKDRETQRSRGFGFVTFENIDDAKDAMMAMN 68
Query: 103 GALLGDRSLRVDIAEGRKQDKGGFGFRKGGPDDRGMGSSRESRGGWDSRDDFNSGFR--- 159
G + R +RVD A G+ D G+R G RG RG SR + G+
Sbjct: 69 GKSVDGRQIRVDQA-GKSSDNRSRGYRGGSAGGRGFFRGGRGRGRGFSRGGGDRGYGGNR 127
Query: 160 -DDFLGGRGGSR 170
+ GG GGSR
Sbjct: 128 FESRSGGYGGSR 139
>gi|4826734 fusion (involved in t(12;16) in malignant liposarcoma)
[Homo sapiens]
Length = 526
Score = 62.4 bits (150), Expect = 4e-10
Identities = 60/218 (27%), Positives = 77/218 (35%), Gaps = 34/218 (15%)
Query: 16 GGGRGSRGSAGG--------------HGSRSQKELPTEPPYTAYVGNLPFNTVQGDIDAI 61
GGGRG RG GG GSR E T +V L N +
Sbjct: 245 GGGRGGRGGMGGSDRGGFNKFGGPRDQGSRHDSEQDNSDNNTIFVQGLGENVTIESVADY 304
Query: 62 FKDLSIRS---------VRLVRDKDTDKFKGFCYVEFDEVDSLKEALT-YDGALLGDRSL 111
FK + I + L D++T K KG V FD+ S K A+ +DG +
Sbjct: 305 FKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSFDDPPSAKAAIDWFDGKEFSGNPI 364
Query: 112 RVDIAEGRKQDKGGFGFRKGGPDDRGMGSSRESRGGWDSRDDFNSGFRDDFLGGRGGSRP 171
+V A R G G +GG RG R GG S GF GG G R
Sbjct: 365 KVSFATRRADFNRGGGNGRGG-RGRGGPMGRGGYGGGGSGGGGRGGFPSGGGGGGGQQRA 423
Query: 172 GDRRTGPPMGSRFRDGPPLRGSNMDFREPTEEERAQRP 209
GD + P N +R + +A +P
Sbjct: 424 GDWKC---------PNPTCENMNFSWRNECNQCKAPKP 452
Score = 29.6 bits (65), Expect = 2.5
Identities = 22/52 (42%), Positives = 23/52 (44%), Gaps = 3/52 (5%)
Query: 124 GGFGFRKGGP--DDRGMGSSRESRGGWDSRDDFNSGFRDDFLGG-RGGSRPG 172
G G GG DDR G RGG+ R GFR GG RGG PG
Sbjct: 458 GPGGSHMGGNYGDDRRGGRGGYDRGGYRGRGGDRGGFRGGRGGGDRGGFGPG 509
Score = 27.7 bits (60), Expect = 9.7
Identities = 12/29 (41%), Positives = 14/29 (48%)
Query: 124 GGFGFRKGGPDDRGMGSSRESRGGWDSRD 152
GG+ GG + RG G R RGG D
Sbjct: 230 GGYNRSSGGYEPRGRGGGRGGRGGMGGSD 258
>gi|238859597 RNA binding motif protein 34 isoform 1 [Homo sapiens]
Length = 430
Score = 52.8 bits (125), Expect = 3e-07
Identities = 32/72 (44%), Positives = 43/72 (59%), Gaps = 1/72 (1%)
Query: 43 TAYVGNLPFNTVQGDIDAIFKDL-SIRSVRLVRDKDTDKFKGFCYVEFDEVDSLKEALTY 101
+ +VGNLP+ + I+ F D SI +VR+VRDK T KGF YV F+ DS+ AL
Sbjct: 288 SVFVGNLPYKVEESAIEKHFLDCGSIMAVRIVRDKMTGIGKGFGYVLFENTDSVHLALKL 347
Query: 102 DGALLGDRSLRV 113
+ + L R LRV
Sbjct: 348 NNSELMGRKLRV 359
Score = 30.4 bits (67), Expect = 1.5
Identities = 32/112 (28%), Positives = 49/112 (43%), Gaps = 20/112 (17%)
Query: 32 SQKELPTEPPYTAYVGNLPFNTVQGDIDAIFKDL-SIRSVR-----------------LV 73
+Q+E + T +VGNLP + + + FK+ I SVR +
Sbjct: 175 NQEEERLKNERTVFVGNLPVTCNKKKLKSFFKEYGQIESVRFRSLIPAEGTLSKKLAAIK 234
Query: 74 RDKDTDKFKGFCYVEFDEVDSLKEALTYDGALLGDR-SLRVDIA-EGRKQDK 123
R D+ YV F E + +AL +GA + D +RVD+A E +DK
Sbjct: 235 RKIHPDQKNINAYVVFKEESAATQALKRNGAQIADGFRIRVDLASETSSRDK 286
>gi|19923387 nuclear cap binding protein subunit 2, 20kDa isoform 1
[Homo sapiens]
Length = 156
Score = 52.8 bits (125), Expect = 3e-07
Identities = 44/142 (30%), Positives = 63/142 (44%), Gaps = 22/142 (15%)
Query: 29 GSRSQKELPTEPPYTAYVGNLPFNTVQGDIDAIF-KDLSIRSVRLVRDKDTDKFKGFCYV 87
G ++E + T YVGNL F T + I +F K I+ + + DK GFC+V
Sbjct: 27 GDNEEQEKLLKKSCTLYVGNLSFYTTEEQIYELFSKSGDIKKIIMGLDKMKKTACGFCFV 86
Query: 88 EFDEVDSLKEALTY-DGALLGDRSLRVDIAEGRKQDKGGFGFRKGGPDDRGMGSSRESRG 146
E+ + A+ Y +G L DR +R D GF++G RG R
Sbjct: 87 EYYSRADAENAMRYINGTRLDDRIIRTD---------WDAGFKEGRQYGRG-------RS 130
Query: 147 GWDSRDDFNSGFRDDFLGGRGG 168
G RD+ +R D+ GRGG
Sbjct: 131 GGQVRDE----YRQDYDAGRGG 148
>gi|253970504 Ewing sarcoma breakpoint region 1 isoform 4 [Homo
sapiens]
Length = 600
Score = 52.4 bits (124), Expect = 4e-07
Identities = 57/210 (27%), Positives = 76/210 (36%), Gaps = 36/210 (17%)
Query: 16 GGGRGSRGSAGGHGSRSQKELPTE--------PPY---------TAYVGNLPFNTVQGDI 58
GGGRG GSAG G ++ P + PP YV L + D+
Sbjct: 262 GGGRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDL 321
Query: 59 DAIFKDLSIRS---------VRLVRDKDTDKFKGFCYVEFDEVDSLKEALT-YDGALLGD 108
FK + + + DK+T K KG V +++ + K A+ +DG
Sbjct: 322 ADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQG 381
Query: 109 RSLRVDIAEGRKQDKGGFGFRKGGPDDRGMGSSRESRGGWDSRDDFNSGFRDDFLGGRGG 168
L+V +A + R G P G G RGG GR G
Sbjct: 382 SKLKVSLARKKPPMNS---MRGGLPPREGRGMPPPLRGGPGGPGGPGGPM------GRMG 432
Query: 169 SRPGDRRTGPPMGSRFRDGPPLRGSNMDFR 198
R GDR PP G R G P G N+ R
Sbjct: 433 GRGGDRGGFPPRGPRGSRGNPSGGGNVQHR 462
Score = 36.6 bits (83), Expect = 0.021
Identities = 27/89 (30%), Positives = 33/89 (37%), Gaps = 18/89 (20%)
Query: 121 QDKGGFGF-----RKGGPDDRGMGSSRESRGGWDSRDDFNSGFRDDFLGGRGGSRPGDRR 175
Q+ GGF GPD+RG G RGG GGRGG R G
Sbjct: 224 QESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSR-------------GGRGGGRGGMGS 270
Query: 176 TGPPMGSRFRDGPPLRGSNMDFREPTEEE 204
G G GP G ++D P + +
Sbjct: 271 AGERGGFNKPGGPMDEGPDLDLGPPVDPD 299
Score = 28.9 bits (63), Expect = 4.3
Identities = 27/69 (39%), Positives = 28/69 (40%), Gaps = 18/69 (26%)
Query: 124 GGFGFRKGGPDDRGMGSSRESRGGWDSRDDFNSGFRDDFLGGRG---GSRPGDRRTGPPM 180
GG +GG DRG G RGG G R F GGRG G G RR GP
Sbjct: 513 GGMRGGRGGLMDRG-GPGGMFRGG-------RGGDRGGFRGGRGMDRGGFGGGRRGGP-- 562
Query: 181 GSRFRDGPP 189
GPP
Sbjct: 563 -----GGPP 566
Score = 28.1 bits (61), Expect = 7.4
Identities = 17/37 (45%), Positives = 19/37 (51%), Gaps = 7/37 (18%)
Query: 118 GRKQDKGGF-GFRKGGPDD------RGMGSSRESRGG 147
GR D+GGF G R+GGP MG R RGG
Sbjct: 546 GRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGG 582
>gi|4885225 Ewing sarcoma breakpoint region 1 isoform 2 [Homo
sapiens]
Length = 656
Score = 52.4 bits (124), Expect = 4e-07
Identities = 57/210 (27%), Positives = 76/210 (36%), Gaps = 36/210 (17%)
Query: 16 GGGRGSRGSAGGHGSRSQKELPTE--------PPY---------TAYVGNLPFNTVQGDI 58
GGGRG GSAG G ++ P + PP YV L + D+
Sbjct: 318 GGGRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDL 377
Query: 59 DAIFKDLSIRS---------VRLVRDKDTDKFKGFCYVEFDEVDSLKEALT-YDGALLGD 108
FK + + + DK+T K KG V +++ + K A+ +DG
Sbjct: 378 ADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQG 437
Query: 109 RSLRVDIAEGRKQDKGGFGFRKGGPDDRGMGSSRESRGGWDSRDDFNSGFRDDFLGGRGG 168
L+V +A + R G P G G RGG GR G
Sbjct: 438 SKLKVSLARKKPPMNS---MRGGLPPREGRGMPPPLRGGPGGPGGPGGPM------GRMG 488
Query: 169 SRPGDRRTGPPMGSRFRDGPPLRGSNMDFR 198
R GDR PP G R G P G N+ R
Sbjct: 489 GRGGDRGGFPPRGPRGSRGNPSGGGNVQHR 518
Score = 36.6 bits (83), Expect = 0.021
Identities = 27/89 (30%), Positives = 33/89 (37%), Gaps = 18/89 (20%)
Query: 121 QDKGGFGF-----RKGGPDDRGMGSSRESRGGWDSRDDFNSGFRDDFLGGRGGSRPGDRR 175
Q+ GGF GPD+RG G RGG GGRGG R G
Sbjct: 280 QESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSR-------------GGRGGGRGGMGS 326
Query: 176 TGPPMGSRFRDGPPLRGSNMDFREPTEEE 204
G G GP G ++D P + +
Sbjct: 327 AGERGGFNKPGGPMDEGPDLDLGPPVDPD 355
Score = 28.9 bits (63), Expect = 4.3
Identities = 27/69 (39%), Positives = 28/69 (40%), Gaps = 18/69 (26%)
Query: 124 GGFGFRKGGPDDRGMGSSRESRGGWDSRDDFNSGFRDDFLGGRG---GSRPGDRRTGPPM 180
GG +GG DRG G RGG G R F GGRG G G RR GP
Sbjct: 569 GGMRGGRGGLMDRG-GPGGMFRGG-------RGGDRGGFRGGRGMDRGGFGGGRRGGP-- 618
Query: 181 GSRFRDGPP 189
GPP
Sbjct: 619 -----GGPP 622
Score = 28.1 bits (61), Expect = 7.4
Identities = 17/37 (45%), Positives = 19/37 (51%), Gaps = 7/37 (18%)
Query: 118 GRKQDKGGF-GFRKGGPDD------RGMGSSRESRGG 147
GR D+GGF G R+GGP MG R RGG
Sbjct: 602 GRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGG 638
>gi|4507353 TBP-associated factor 15 isoform 2 [Homo sapiens]
Length = 589
Score = 50.8 bits (120), Expect = 1e-06
Identities = 53/176 (30%), Positives = 68/176 (38%), Gaps = 35/176 (19%)
Query: 14 SFGGGRGSRGSAGGH---GSRSQ--KELPTEPPYTAYVGNLPFNTVQGDIDAIFKDLSIR 68
S GG RG + GGH G R+ E T +V L + FK + I
Sbjct: 198 SSGGDRGGFKNFGGHRDYGPRTDADSESDNSDNNTIFVQGLGEGVSTDQVGEFFKQIGII 257
Query: 69 S---------VRLVRDKDTDKFKGFCYVEFDEVDSLKEALT-YDGALLGDRSLRVDIAEG 118
+ L DKDT K KG V FD+ S K A+ +DG ++V A
Sbjct: 258 KTNKKTGKPMINLYTDKDTGKPKGEATVSFDDPPSAKAAIDWFDGKEFHGNIIKVSFATR 317
Query: 119 RKQDKGGFGFRKGGPDDRGMGSSRESRGGWDSRDDFNSGFRDDFLGGRGGS-RPGD 173
R + F +GG G G R RGG+ R F GRGG + GD
Sbjct: 318 RPE------FMRGG----GSGGGRRGRGGYRGRGGFQ---------GRGGDPKSGD 354
Score = 39.7 bits (91), Expect = 0.002
Identities = 31/82 (37%), Positives = 38/82 (46%), Gaps = 6/82 (7%)
Query: 122 DKGGFGFRKGG-PDDRGMGSSRESRGGWDSRDDFNSGFRDDFLGGRGGSRP----GDRRT 176
D+GG+G +GG DRG SRGG+ SG+ D GG GG R G R
Sbjct: 501 DRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDRG 560
Query: 177 GPPMGSRFRDGPPLRGSNMDFR 198
G G R G + G N D+R
Sbjct: 561 GGYGGDRGGYGGKMGGRN-DYR 581
Score = 36.2 bits (82), Expect = 0.027
Identities = 26/65 (40%), Positives = 31/65 (47%), Gaps = 9/65 (13%)
Query: 118 GRKQDKGGFGFRKGGPDDRGMGSSRESRGGWDSRDDFNSGFRDDFLGG-----RGGSRPG 172
GR D+GG+G + G G G R S GG+ S D G+ D GG RGG G
Sbjct: 407 GRGGDRGGYGGDRSG---GGYGGDRSSGGGY-SGDRSGGGYGGDRSGGGYGGDRGGGYGG 462
Query: 173 DRRTG 177
DR G
Sbjct: 463 DRGGG 467
Score = 30.0 bits (66), Expect = 2.0
Identities = 25/74 (33%), Positives = 30/74 (40%), Gaps = 5/74 (6%)
Query: 103 GALLGDRSLRVDIAEGRKQDKGGFGFRKGGP--DDRGMGSSRESRGGWDSRDDFNSGFRD 160
G GDRS G + GG+G +GG DRG G + GG+ G R
Sbjct: 432 GGYSGDRS---GGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRG 488
Query: 161 DFLGGRGGSRPGDR 174
GG G GDR
Sbjct: 489 GGYGGDRGGYGGDR 502
Score = 28.1 bits (61), Expect = 7.4
Identities = 16/46 (34%), Positives = 21/46 (45%), Gaps = 3/46 (6%)
Query: 132 GPDDRGMGSSRESRGGWDSRDDFNSGFRDDFLGGRGGSRPGDRRTG 177
G D+RG G S+ GG R ++ R G GG R G + G
Sbjct: 168 GEDNRGYGGSQ---GGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFG 210
>gi|21327701 TBP-associated factor 15 isoform 1 [Homo sapiens]
Length = 592
Score = 50.8 bits (120), Expect = 1e-06
Identities = 53/176 (30%), Positives = 68/176 (38%), Gaps = 35/176 (19%)
Query: 14 SFGGGRGSRGSAGGH---GSRSQ--KELPTEPPYTAYVGNLPFNTVQGDIDAIFKDLSIR 68
S GG RG + GGH G R+ E T +V L + FK + I
Sbjct: 201 SSGGDRGGFKNFGGHRDYGPRTDADSESDNSDNNTIFVQGLGEGVSTDQVGEFFKQIGII 260
Query: 69 S---------VRLVRDKDTDKFKGFCYVEFDEVDSLKEALT-YDGALLGDRSLRVDIAEG 118
+ L DKDT K KG V FD+ S K A+ +DG ++V A
Sbjct: 261 KTNKKTGKPMINLYTDKDTGKPKGEATVSFDDPPSAKAAIDWFDGKEFHGNIIKVSFATR 320
Query: 119 RKQDKGGFGFRKGGPDDRGMGSSRESRGGWDSRDDFNSGFRDDFLGGRGGS-RPGD 173
R + F +GG G G R RGG+ R F GRGG + GD
Sbjct: 321 RPE------FMRGG----GSGGGRRGRGGYRGRGGFQ---------GRGGDPKSGD 357
Score = 39.7 bits (91), Expect = 0.002
Identities = 31/82 (37%), Positives = 38/82 (46%), Gaps = 6/82 (7%)
Query: 122 DKGGFGFRKGG-PDDRGMGSSRESRGGWDSRDDFNSGFRDDFLGGRGGSRP----GDRRT 176
D+GG+G +GG DRG SRGG+ SG+ D GG GG R G R
Sbjct: 504 DRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDRG 563
Query: 177 GPPMGSRFRDGPPLRGSNMDFR 198
G G R G + G N D+R
Sbjct: 564 GGYGGDRGGYGGKMGGRN-DYR 584
Score = 36.2 bits (82), Expect = 0.027
Identities = 26/65 (40%), Positives = 31/65 (47%), Gaps = 9/65 (13%)
Query: 118 GRKQDKGGFGFRKGGPDDRGMGSSRESRGGWDSRDDFNSGFRDDFLGG-----RGGSRPG 172
GR D+GG+G + G G G R S GG+ S D G+ D GG RGG G
Sbjct: 410 GRGGDRGGYGGDRSG---GGYGGDRSSGGGY-SGDRSGGGYGGDRSGGGYGGDRGGGYGG 465
Query: 173 DRRTG 177
DR G
Sbjct: 466 DRGGG 470
Score = 30.0 bits (66), Expect = 2.0
Identities = 25/74 (33%), Positives = 30/74 (40%), Gaps = 5/74 (6%)
Query: 103 GALLGDRSLRVDIAEGRKQDKGGFGFRKGGP--DDRGMGSSRESRGGWDSRDDFNSGFRD 160
G GDRS G + GG+G +GG DRG G + GG+ G R
Sbjct: 435 GGYSGDRS---GGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRG 491
Query: 161 DFLGGRGGSRPGDR 174
GG G GDR
Sbjct: 492 GGYGGDRGGYGGDR 505
Score = 28.1 bits (61), Expect = 7.4
Identities = 16/46 (34%), Positives = 21/46 (45%), Gaps = 3/46 (6%)
Query: 132 GPDDRGMGSSRESRGGWDSRDDFNSGFRDDFLGGRGGSRPGDRRTG 177
G D+RG G S+ GG R ++ R G GG R G + G
Sbjct: 171 GEDNRGYGGSQ---GGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFG 213
>gi|56699409 RNA binding motif protein, X-linked [Homo sapiens]
Length = 391
Score = 50.8 bits (120), Expect = 1e-06
Identities = 58/203 (28%), Positives = 86/203 (42%), Gaps = 32/203 (15%)
Query: 41 PYTAYVGNLPFNTVQGDIDAIF-KDLSIRSVRLVRDKDTDKFKGFCYVEFDE-VDSLKEA 98
P ++G L T + ++A+F K I V L++D++T+K +GF +V F+ D+ A
Sbjct: 7 PGKLFIGGLNTETNEKALEAVFGKYGRIVEVLLMKDRETNKSRGFAFVTFESPADAKDAA 66
Query: 99 LTYDGALLGDRSLRVDIAEGRKQDKGGFGFRKG-GPDDRGMGSSRESRGGWDSRDDFNSG 157
+G L ++++V+ A + G R+G P R G R RGG
Sbjct: 67 RDMNGKSLDGKAIKVEQATKPSFESG----RRGPPPPPRSRGPPRGLRGG---------- 112
Query: 158 FRDDFLGGRGGSRPGDRRTGPP-MGSRFRDGPPLRGSNM-DFREPTEEERAQRPRLQLKP 215
GG GG+R GPP G DG NM R P +R PR P
Sbjct: 113 -----RGGSGGTR------GPPSRGGHMDDGGYSMNFNMSSSRGPLPVKRGPPPRSGGPP 161
Query: 216 RTVATPLNQVANPNSAIFGGARP 238
+ P V +S+ GG P
Sbjct: 162 PKRSAPSGPVR--SSSGMGGRAP 182
>gi|118600973 RNA binding motif protein, X-linked 2 [Homo sapiens]
Length = 322
Score = 49.7 bits (117), Expect = 2e-06
Identities = 26/72 (36%), Positives = 44/72 (61%), Gaps = 2/72 (2%)
Query: 45 YVGNLPFNTVQGDIDAIFKDLS-IRSVRLVRDKDTDKFKGFCYVEFDEVDSLKEAL-TYD 102
++G LP+ +GDI +F I ++ LVRDK T K KGFC++ +++ S A+ ++
Sbjct: 39 FLGGLPYELTEGDIICVFSQYGEIVNINLVRDKKTGKSKGFCFLCYEDQRSTILAVDNFN 98
Query: 103 GALLGDRSLRVD 114
G + R++RVD
Sbjct: 99 GIKIKGRTIRVD 110
>gi|14110407 heterogeneous nuclear ribonucleoprotein D-like [Homo
sapiens]
Length = 420
Score = 48.5 bits (114), Expect = 5e-06
Identities = 35/138 (25%), Positives = 62/138 (44%), Gaps = 11/138 (7%)
Query: 39 EPPYTAYVGNLPFNTVQGDIDAIFKDLS-IRSVRLVRDKDTDKFKGFCYVEFDEVDSLKE 97
EPP +VG L +T + I F I ++ L D T++ +GFC++ + + + +K+
Sbjct: 230 EPPKKVFVGGLSPDTSEEQIKEYFGAFGEIENIELPMDTKTNERRGFCFITYTDEEPVKK 289
Query: 98 ALTYDGALLGDRSLRVDIAEGR-------KQDKGGFGFR---KGGPDDRGMGSSRESRGG 147
L +G + +A+ + +Q KGG G +GG RG G + G
Sbjct: 290 LLESRYHQIGSGKCEIKVAQPKEVYRQQQQQQKGGRGAAAGGRGGTRGRGRGQGQNWNQG 349
Query: 148 WDSRDDFNSGFRDDFLGG 165
+++ D G + GG
Sbjct: 350 FNNYYDQGYGNYNSAYGG 367
>gi|4759098 splicing factor, arginine/serine-rich 10 [Homo sapiens]
Length = 288
Score = 48.5 bits (114), Expect = 5e-06
Identities = 43/138 (31%), Positives = 62/138 (44%), Gaps = 12/138 (8%)
Query: 46 VGNLPFNTVQGDIDAIFKDLS-IRSVRLVRDKDTDKFKGFCYVEFDEVDSLKEAL-TYDG 103
V L T + D+ +F I V +V D+ + + +GF +V F+ VD KEA +G
Sbjct: 122 VFGLSLYTTERDLREVFSKYGPIADVSIVYDQQSRRSRGFAFVYFENVDDAKEAKERANG 181
Query: 104 ALLGDRSLRVDIAEGRKQDKGGFGFRKGGPDDRGMGSSRE----SRG---GWDSRDDFNS 156
L R +RVD + ++ G G P GSSR RG G+D RD ++
Sbjct: 182 MELDGRRIRVDFSITKRPHTPTPGIYMGRPT---YGSSRRRDYYDRGYDRGYDDRDYYSR 238
Query: 157 GFRDDFLGGRGGSRPGDR 174
+R GG G DR
Sbjct: 239 SYRGGGGGGGGWRAAQDR 256
>gi|9558733 transformer-2 alpha [Homo sapiens]
Length = 282
Score = 48.1 bits (113), Expect = 7e-06
Identities = 47/161 (29%), Positives = 69/161 (42%), Gaps = 35/161 (21%)
Query: 46 VGNLPFNTVQGDIDAIFKDLS-IRSVRLVRDKDTDKFKGFCYVEFDEVDSLKEAL-TYDG 103
V L T + D+ +F + V +V D+ T + +GF +V F+ +D KEA+ +G
Sbjct: 123 VFGLSLYTTERDLREVFSRYGPLSGVNVVYDQRTGRSRGFAFVYFERIDDSKEAMERANG 182
Query: 104 ALLGDRSLRVD-------------IAEGRKQDKGGFGFRKGGPDDRGMGSSRES---RG- 146
L R +RVD I GR GG G GG G G R+S RG
Sbjct: 183 MELDGRRIRVDYSITKRAHTPTPGIYMGRPTHSGGGGGGGGGGGGGGGGRRRDSYYDRGY 242
Query: 147 --GWDSRDDFNSGFRDDFLGGRGGSRPGDRRTGPPMGSRFR 185
G+D +D++ +R RR+ P SR+R
Sbjct: 243 DRGYDRYEDYDYRYR--------------RRSPSPYYSRYR 269
>gi|153252068 testes-specific heterogenous nuclear ribonucleoprotein
G-T [Homo sapiens]
Length = 392
Score = 47.4 bits (111), Expect = 1e-05
Identities = 57/207 (27%), Positives = 83/207 (40%), Gaps = 31/207 (14%)
Query: 41 PYTAYVGNLPFNTVQGDIDAIF-KDLSIRSVRLVRDKDTDKFKGFCYVEFDE-VDSLKEA 98
P ++G L T + ++A F K I V L++D++T+K +GF +V F+ D+ A
Sbjct: 7 PGKLFIGGLNLETDEKALEAEFGKYGRIVEVLLMKDRETNKSRGFAFVTFESPADAKAAA 66
Query: 99 LTYDGALLGDRSLRVDIAEGRKQDKGGF-GFRKGGPDDRGMGSSRESRGGWDSRDDFNSG 157
+G L ++++V + K F R+G P R G R RG
Sbjct: 67 RDMNGKSLDGKAIKV-----AQATKPAFESSRRGPPPPRSRGRPRFLRG----------- 110
Query: 158 FRDDFLGGRGGSRPGDRRTGPPMGSRFRDGPPLRGSNMDFREPTEEERAQRPRLQLKPRT 217
GG GG R R GP + LR S R P +R PR P
Sbjct: 111 ----TRGGGGGPRRSPSRGGPDDDGGYTADFDLRPS----RAPMPMKRGPPPRRVGPPPK 162
Query: 218 VATPLNQVANPNSAIFGGARPREEVVQ 244
A P + P + GG R R V+
Sbjct: 163 RAAP----SGPARSSGGGMRGRALAVR 185
>gi|5803137 RNA binding motif protein 3 [Homo sapiens]
Length = 157
Score = 47.4 bits (111), Expect = 1e-05
Identities = 47/142 (33%), Positives = 69/142 (48%), Gaps = 22/142 (15%)
Query: 45 YVGNLPFNTVQGDIDAIFKDLS-IRSVRLVRDKDTDKFKGFCYVEFDEVDSLKEAL-TYD 102
+VG L FNT + ++ F I V +V+D++T + +GF ++ F + A+ +
Sbjct: 9 FVGGLNFNTDEQALEDHFSSFGPISEVVVVKDRETQRSRGFGFITFTNPEHASVAMRAMN 68
Query: 103 GALLGDRSLRVDIA--EGRKQDKGGFG-------FRKGGPDDRGMGSSR--ESR-GGWD- 149
G L R +RVD A R GGFG + +GG D+G GS R +SR GG+
Sbjct: 69 GESLDGRQIRVDHAGKSARGTRGGGFGAHGRGRSYSRGG-GDQGYGSGRYYDSRPGGYGY 127
Query: 150 ----SRD--DFNSGFRDDFLGG 165
SRD N G D + GG
Sbjct: 128 GYGRSRDYNGRNQGGYDRYSGG 149
>gi|14149675 cleavage stimulation factor, 3' pre-RNA, subunit 2,
64kDa, tau variant [Homo sapiens]
Length = 616
Score = 47.4 bits (111), Expect = 1e-05
Identities = 27/80 (33%), Positives = 45/80 (56%), Gaps = 2/80 (2%)
Query: 43 TAYVGNLPFNTVQGDIDAIFKDL-SIRSVRLVRDKDTDKFKGFCYVEF-DEVDSLKEALT 100
+ +VGN+P+ + + IF ++ S+ S RLV D++T K KG+ + E+ D+ +L
Sbjct: 17 SVFVGNIPYEATEEQLKDIFSEVGSVVSFRLVYDRETGKPKGYGFCEYQDQETALSAMRN 76
Query: 101 YDGALLGDRSLRVDIAEGRK 120
+G R+LRVD A K
Sbjct: 77 LNGREFSGRALRVDNAASEK 96
>gi|14110420 heterogeneous nuclear ribonucleoprotein D isoform a
[Homo sapiens]
Length = 355
Score = 47.0 bits (110), Expect = 2e-05
Identities = 38/142 (26%), Positives = 62/142 (43%), Gaps = 15/142 (10%)
Query: 39 EPPYTAYVGNLPFNTVQGDIDAIFKDLS-IRSVRLVRDKDTDKFKGFCYVEFDEVDSLKE 97
EP +VG L +T + I F + S+ L D T+K +GFC++ F E + +K+
Sbjct: 179 EPVKKIFVGGLSPDTPEEKIREYFGGFGEVESIELPMDNKTNKRRGFCFITFKEEEPVKK 238
Query: 98 ALTYDGALLGDRSLRVDIAEGRKQ--------DKGGFGFRKGGPDDRGMGSSRESRGGWD 149
+ +G + +A ++Q +GGF R G RG G S+ G+
Sbjct: 239 IMEKKYHNVGLSKCEIKVAMSKEQYQQQQQWGSRGGFAGRARG---RGGGPSQNWNQGYS 295
Query: 150 ---SRDDFNSGFRDDFLGGRGG 168
++ N G+ GG GG
Sbjct: 296 NYWNQGYGNYGYNSQGYGGYGG 317
>gi|14110417 heterogeneous nuclear ribonucleoprotein D isoform b
[Homo sapiens]
Length = 336
Score = 47.0 bits (110), Expect = 2e-05
Identities = 38/142 (26%), Positives = 62/142 (43%), Gaps = 15/142 (10%)
Query: 39 EPPYTAYVGNLPFNTVQGDIDAIFKDLS-IRSVRLVRDKDTDKFKGFCYVEFDEVDSLKE 97
EP +VG L +T + I F + S+ L D T+K +GFC++ F E + +K+
Sbjct: 160 EPVKKIFVGGLSPDTPEEKIREYFGGFGEVESIELPMDNKTNKRRGFCFITFKEEEPVKK 219
Query: 98 ALTYDGALLGDRSLRVDIAEGRKQ--------DKGGFGFRKGGPDDRGMGSSRESRGGWD 149
+ +G + +A ++Q +GGF R G RG G S+ G+
Sbjct: 220 IMEKKYHNVGLSKCEIKVAMSKEQYQQQQQWGSRGGFAGRARG---RGGGPSQNWNQGYS 276
Query: 150 ---SRDDFNSGFRDDFLGGRGG 168
++ N G+ GG GG
Sbjct: 277 NYWNQGYGNYGYNSQGYGGYGG 298
Score = 33.5 bits (75), Expect = 0.18
Identities = 23/89 (25%), Positives = 40/89 (44%), Gaps = 5/89 (5%)
Query: 16 GGGRGSRGSAGG----HGSRSQKELPTEPPYTAYVGNLPFNTVQGDIDAIFKDL-SIRSV 70
GGG S G+ GG G++ E ++G L ++T + D+ F +
Sbjct: 48 GGGTASGGTEGGSAESEGAKIDASKNEEDEGKMFIGGLSWDTTKKDLKDYFSKFGEVVDC 107
Query: 71 RLVRDKDTDKFKGFCYVEFDEVDSLKEAL 99
L D T + +GF +V F E +S+ + +
Sbjct: 108 TLKLDPITGRSRGFGFVLFKESESVDKVM 136
>gi|253970502 Ewing sarcoma breakpoint region 1 isoform 3 [Homo
sapiens]
Length = 655
Score = 46.2 bits (108), Expect = 3e-05
Identities = 56/210 (26%), Positives = 75/210 (35%), Gaps = 37/210 (17%)
Query: 16 GGGRGSRGSAGGHGSRSQKELPTE--------PPY---------TAYVGNLPFNTVQGDI 58
GGGRG G AG G ++ P + PP YV L + D+
Sbjct: 318 GGGRGGMG-AGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDL 376
Query: 59 DAIFKDLSIRS---------VRLVRDKDTDKFKGFCYVEFDEVDSLKEALT-YDGALLGD 108
FK + + + DK+T K KG V +++ + K A+ +DG
Sbjct: 377 ADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQG 436
Query: 109 RSLRVDIAEGRKQDKGGFGFRKGGPDDRGMGSSRESRGGWDSRDDFNSGFRDDFLGGRGG 168
L+V +A + R G P G G RGG GR G
Sbjct: 437 SKLKVSLARKKPPMNS---MRGGLPPREGRGMPPPLRGGPGGPGGPGGPM------GRMG 487
Query: 169 SRPGDRRTGPPMGSRFRDGPPLRGSNMDFR 198
R GDR PP G R G P G N+ R
Sbjct: 488 GRGGDRGGFPPRGPRGSRGNPSGGGNVQHR 517
Score = 35.0 bits (79), Expect = 0.061
Identities = 30/78 (38%), Positives = 36/78 (46%), Gaps = 14/78 (17%)
Query: 121 QDKGGFGF-----RKGGPDDRGMGSSRESRGGWDSRDDFNSGFRDDFLGGRG-GSRPGDR 174
Q+ GGF GPD+RG G RGG+D R + G R GG G G R G
Sbjct: 280 QESGGFSGPGENRSMSGPDNRGRG-----RGGFD-RGGMSRGGRGGGRGGMGAGERGGFN 333
Query: 175 RTGPPM--GSRFRDGPPL 190
+ G PM G GPP+
Sbjct: 334 KPGGPMDEGPDLDLGPPV 351
Score = 28.9 bits (63), Expect = 4.3
Identities = 27/69 (39%), Positives = 28/69 (40%), Gaps = 18/69 (26%)
Query: 124 GGFGFRKGGPDDRGMGSSRESRGGWDSRDDFNSGFRDDFLGGRG---GSRPGDRRTGPPM 180
GG +GG DRG G RGG G R F GGRG G G RR GP
Sbjct: 568 GGMRGGRGGLMDRG-GPGGMFRGG-------RGGDRGGFRGGRGMDRGGFGGGRRGGP-- 617
Query: 181 GSRFRDGPP 189
GPP
Sbjct: 618 -----GGPP 621
Score = 28.1 bits (61), Expect = 7.4
Identities = 17/37 (45%), Positives = 19/37 (51%), Gaps = 7/37 (18%)
Query: 118 GRKQDKGGF-GFRKGGPDD------RGMGSSRESRGG 147
GR D+GGF G R+GGP MG R RGG
Sbjct: 601 GRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGG 637
>gi|253970500 Ewing sarcoma breakpoint region 1 isoform 1 [Homo
sapiens]
Length = 661
Score = 46.2 bits (108), Expect = 3e-05
Identities = 56/210 (26%), Positives = 75/210 (35%), Gaps = 37/210 (17%)
Query: 16 GGGRGSRGSAGGHGSRSQKELPTE--------PPY---------TAYVGNLPFNTVQGDI 58
GGGRG G AG G ++ P + PP YV L + D+
Sbjct: 324 GGGRGGMG-AGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDL 382
Query: 59 DAIFKDLSIRS---------VRLVRDKDTDKFKGFCYVEFDEVDSLKEALT-YDGALLGD 108
FK + + + DK+T K KG V +++ + K A+ +DG
Sbjct: 383 ADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQG 442
Query: 109 RSLRVDIAEGRKQDKGGFGFRKGGPDDRGMGSSRESRGGWDSRDDFNSGFRDDFLGGRGG 168
L+V +A + R G P G G RGG GR G
Sbjct: 443 SKLKVSLARKKPPMNS---MRGGLPPREGRGMPPPLRGGPGGPGGPGGPM------GRMG 493
Query: 169 SRPGDRRTGPPMGSRFRDGPPLRGSNMDFR 198
R GDR PP G R G P G N+ R
Sbjct: 494 GRGGDRGGFPPRGPRGSRGNPSGGGNVQHR 523
Score = 35.0 bits (79), Expect = 0.061
Identities = 30/78 (38%), Positives = 36/78 (46%), Gaps = 14/78 (17%)
Query: 121 QDKGGFGF-----RKGGPDDRGMGSSRESRGGWDSRDDFNSGFRDDFLGGRG-GSRPGDR 174
Q+ GGF GPD+RG G RGG+D R + G R GG G G R G
Sbjct: 286 QESGGFSGPGENRSMSGPDNRGRG-----RGGFD-RGGMSRGGRGGGRGGMGAGERGGFN 339
Query: 175 RTGPPM--GSRFRDGPPL 190
+ G PM G GPP+
Sbjct: 340 KPGGPMDEGPDLDLGPPV 357
Score = 28.9 bits (63), Expect = 4.3
Identities = 27/69 (39%), Positives = 28/69 (40%), Gaps = 18/69 (26%)
Query: 124 GGFGFRKGGPDDRGMGSSRESRGGWDSRDDFNSGFRDDFLGGRG---GSRPGDRRTGPPM 180
GG +GG DRG G RGG G R F GGRG G G RR GP
Sbjct: 574 GGMRGGRGGLMDRG-GPGGMFRGG-------RGGDRGGFRGGRGMDRGGFGGGRRGGP-- 623
Query: 181 GSRFRDGPP 189
GPP
Sbjct: 624 -----GGPP 627
Score = 28.1 bits (61), Expect = 7.4
Identities = 17/37 (45%), Positives = 19/37 (51%), Gaps = 7/37 (18%)
Query: 118 GRKQDKGGF-GFRKGGPDD------RGMGSSRESRGG 147
GR D+GGF G R+GGP MG R RGG
Sbjct: 607 GRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGG 643
>gi|4557493 cleavage stimulation factor subunit 2 [Homo sapiens]
Length = 577
Score = 46.2 bits (108), Expect = 3e-05
Identities = 28/93 (30%), Positives = 47/93 (50%), Gaps = 2/93 (2%)
Query: 43 TAYVGNLPFNTVQGDIDAIFKDLS-IRSVRLVRDKDTDKFKGFCYVEF-DEVDSLKEALT 100
+ +VGN+P+ + + IF ++ + S RLV D++T K KG+ + E+ D+ +L
Sbjct: 17 SVFVGNIPYEATEEQLKDIFSEVGPVVSFRLVYDRETGKPKGYGFCEYQDQETALSAMRN 76
Query: 101 YDGALLGDRSLRVDIAEGRKQDKGGFGFRKGGP 133
+G R+LRVD A K + G P
Sbjct: 77 LNGREFSGRALRVDNAASEKNKEELKSLGTGAP 109
>gi|242117971 RNA binding motif protein, X-linked-like 1 [Homo
sapiens]
Length = 390
Score = 45.8 bits (107), Expect = 3e-05
Identities = 47/173 (27%), Positives = 71/173 (41%), Gaps = 26/173 (15%)
Query: 41 PYTAYVGNLPFNTVQGDIDAIF-KDLSIRSVRLVRDKDTDKFKGFCYVEFDE-VDSLKEA 98
P ++G L T + ++ +F K I V L++D++T+K +GF +V F+ D+ A
Sbjct: 7 PGKLFIGGLNTETNEKALETVFGKYGRIVEVLLIKDRETNKSRGFAFVTFESPADAKDAA 66
Query: 99 LTYDGALLGDRSLRVDIAEGRKQDKGGFGFRKGGPDDRGMGSSRESRGGWDSRDDFNSGF 158
+G L ++++V+ A ++G G P R G R
Sbjct: 67 RDMNGKSLDGKAIKVEQATKPSFERGRHG---PPPPPRSRGPPR---------------- 107
Query: 159 RDDFLGGRGGSRPGDRRTGPPMGSRFRDGPPLRGSNM-DFREPTEEERAQRPR 210
F GRGGS G R P G DG NM R P +R PR
Sbjct: 108 --GFGAGRGGS--GGTRGPPSRGGHMDDGGYSMNFNMSSSRGPLPVKRGPPPR 156
>gi|21361809 RNA binding motif protein, X-linked-like 1 [Homo
sapiens]
Length = 390
Score = 45.8 bits (107), Expect = 3e-05
Identities = 47/173 (27%), Positives = 71/173 (41%), Gaps = 26/173 (15%)
Query: 41 PYTAYVGNLPFNTVQGDIDAIF-KDLSIRSVRLVRDKDTDKFKGFCYVEFDE-VDSLKEA 98
P ++G L T + ++ +F K I V L++D++T+K +GF +V F+ D+ A
Sbjct: 7 PGKLFIGGLNTETNEKALETVFGKYGRIVEVLLIKDRETNKSRGFAFVTFESPADAKDAA 66
Query: 99 LTYDGALLGDRSLRVDIAEGRKQDKGGFGFRKGGPDDRGMGSSRESRGGWDSRDDFNSGF 158
+G L ++++V+ A ++G G P R G R
Sbjct: 67 RDMNGKSLDGKAIKVEQATKPSFERGRHG---PPPPPRSRGPPR---------------- 107
Query: 159 RDDFLGGRGGSRPGDRRTGPPMGSRFRDGPPLRGSNM-DFREPTEEERAQRPR 210
F GRGGS G R P G DG NM R P +R PR
Sbjct: 108 --GFGAGRGGS--GGTRGPPSRGGHMDDGGYSMNFNMSSSRGPLPVKRGPPPR 156
>gi|29568103 U1 small nuclear ribonucleoprotein 70 kDa [Homo
sapiens]
Length = 437
Score = 45.1 bits (105), Expect = 6e-05
Identities = 47/177 (26%), Positives = 79/177 (44%), Gaps = 23/177 (12%)
Query: 43 TAYVGNLPFNTVQGDIDAIFKDLS-IRSVRLVRDKDTDKFKGFCYVEFDEVDSLKEALTY 101
T +V + ++T + + F+ I+ + +V K + K +G+ ++E++ + A +
Sbjct: 104 TLFVARVNYDTTESKLRREFEVYGPIKRIHMVYSKRSGKPRGYAFIEYEHERDMHSAYKH 163
Query: 102 -DGALLGDRSLRVDIAEGRKQDKGGFGFRKGGPDDRGMGSSRESRGGWDSRDDFNSGFRD 160
DG + R + VD+ GR KG R GG G+G +R RGG D +
Sbjct: 164 ADGKKIDGRRVLVDVERGRTV-KGWRPRRLGG----GLGGTR--RGGADVNIRHS----- 211
Query: 161 DFLGGRGGSRPGDRRTGP-PMGSRFRDGPPLRGSNMDFREPTEEERAQRPRLQLKPR 216
GR + D R GP P+ R RD R + RE + E +R R + + R
Sbjct: 212 ----GRDDTSRYDERPGPSPLPHRDRD----RDRERERRERSRERDKERERRRSRSR 260
>gi|14043070 heterogeneous nuclear ribonucleoprotein A1 isoform b
[Homo sapiens]
Length = 372
Score = 44.3 bits (103), Expect = 1e-04
Identities = 31/129 (24%), Positives = 57/129 (44%), Gaps = 3/129 (2%)
Query: 45 YVGNLPFNTVQGDIDAIFKDLS-IRSVRLVRDKDTDKFKGFCYVEFDEVDSLKEALTYDG 103
+VG + +T + + F+ I + ++ D+ + K +GF +V FD+ DS+ + +
Sbjct: 108 FVGGIKEDTEEHHLRDYFEQYGKIEVIEIMTDRGSGKKRGFAFVTFDDHDSVDKIVIQKY 167
Query: 104 ALLGDRSLRVDIAEGRKQDKGGFGFRKGGPDDRGMGSSRESRGGWDSRDDFNSGFRDDFL 163
+ + V A +++ ++G G R GG+ D+F G
Sbjct: 168 HTVNGHNCEVRKALSKQEMASASSSQRGRSGSGNFGGGR--GGGFGGNDNFGRGGNFSGR 225
Query: 164 GGRGGSRPG 172
GG GGSR G
Sbjct: 226 GGFGGSRGG 234
Score = 31.2 bits (69), Expect = 0.88
Identities = 26/95 (27%), Positives = 34/95 (35%), Gaps = 18/95 (18%)
Query: 124 GGFGFRKGGPDDRGMGSSRESRGGWDSRDDFNSGFRDDFLGGRGGSRPG----------- 172
G G+ GG +G G+ GG S D +N+G F GG G + G
Sbjct: 263 GSRGYGSGG---QGYGNQGSGYGGSGSYDSYNNGGGGGFGGGSGSNFGGGGSYNDFGNYN 319
Query: 173 --DRRTGPPMGSRF--RDGPPLRGSNMDFREPTEE 203
GP G F R P G F +P +
Sbjct: 320 NQSSNFGPMKGGNFGGRSSGPYGGGGQYFAKPRNQ 354
Score = 30.4 bits (67), Expect = 1.5
Identities = 18/71 (25%), Positives = 36/71 (50%), Gaps = 3/71 (4%)
Query: 32 SQKELPTEPPYTA--YVGNLPFNTVQGDIDAIFKDL-SIRSVRLVRDKDTDKFKGFCYVE 88
S+ E P EP ++G L F T + + F+ ++ ++RD +T + +GF +V
Sbjct: 2 SKSESPKEPEQLRKLFIGGLSFETTDESLRSHFEQWGTLTDCVVMRDPNTKRSRGFGFVT 61
Query: 89 FDEVDSLKEAL 99
+ V+ + A+
Sbjct: 62 YATVEEVDAAM 72
>gi|4504445 heterogeneous nuclear ribonucleoprotein A1 isoform a
[Homo sapiens]
Length = 320
Score = 44.3 bits (103), Expect = 1e-04
Identities = 31/129 (24%), Positives = 57/129 (44%), Gaps = 3/129 (2%)
Query: 45 YVGNLPFNTVQGDIDAIFKDLS-IRSVRLVRDKDTDKFKGFCYVEFDEVDSLKEALTYDG 103
+VG + +T + + F+ I + ++ D+ + K +GF +V FD+ DS+ + +
Sbjct: 108 FVGGIKEDTEEHHLRDYFEQYGKIEVIEIMTDRGSGKKRGFAFVTFDDHDSVDKIVIQKY 167
Query: 104 ALLGDRSLRVDIAEGRKQDKGGFGFRKGGPDDRGMGSSRESRGGWDSRDDFNSGFRDDFL 163
+ + V A +++ ++G G R GG+ D+F G
Sbjct: 168 HTVNGHNCEVRKALSKQEMASASSSQRGRSGSGNFGGGR--GGGFGGNDNFGRGGNFSGR 225
Query: 164 GGRGGSRPG 172
GG GGSR G
Sbjct: 226 GGFGGSRGG 234
Score = 30.4 bits (67), Expect = 1.5
Identities = 18/71 (25%), Positives = 36/71 (50%), Gaps = 3/71 (4%)
Query: 32 SQKELPTEPPYTA--YVGNLPFNTVQGDIDAIFKDL-SIRSVRLVRDKDTDKFKGFCYVE 88
S+ E P EP ++G L F T + + F+ ++ ++RD +T + +GF +V
Sbjct: 2 SKSESPKEPEQLRKLFIGGLSFETTDESLRSHFEQWGTLTDCVVMRDPNTKRSRGFGFVT 61
Query: 89 FDEVDSLKEAL 99
+ V+ + A+
Sbjct: 62 YATVEEVDAAM 72
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.139 0.415
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,582,581
Number of Sequences: 37866
Number of extensions: 645805
Number of successful extensions: 3144
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 80
Number of HSP's successfully gapped in prelim test: 144
Number of HSP's that attempted gapping in prelim test: 2674
Number of HSP's gapped (non-prelim): 565
length of query: 248
length of database: 18,247,518
effective HSP length: 100
effective length of query: 148
effective length of database: 14,460,918
effective search space: 2140215864
effective search space used: 2140215864
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.