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Search of human proteins with 115583654
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|115583654 hepatocyte nuclear factor 4, gamma [Homo sapiens]
(445 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|115583654 hepatocyte nuclear factor 4, gamma [Homo sapiens] 898 0.0
gi|31077207 hepatocyte nuclear factor 4 alpha isoform a [Homo sa... 651 0.0
gi|31077205 hepatocyte nuclear factor 4 alpha isoform b [Homo sa... 642 0.0
gi|71725341 hepatocyte nuclear factor 4 alpha isoform e [Homo sa... 616 e-176
gi|71725339 hepatocyte nuclear factor 4 alpha isoform d [Homo sa... 607 e-174
gi|31077209 hepatocyte nuclear factor 4 alpha isoform c [Homo sa... 586 e-167
gi|71725336 hepatocyte nuclear factor 4 alpha isoform f [Homo sa... 551 e-157
gi|11415052 retinoid X receptor, beta [Homo sapiens] 268 1e-71
gi|4506755 retinoid X receptor, alpha [Homo sapiens] 264 1e-70
gi|5902068 retinoid X receptor, gamma isoform a [Homo sapiens] 257 1e-68
gi|20070199 nuclear receptor subfamily 2, group F, member 6 [Hom... 219 4e-57
gi|14149746 nuclear receptor subfamily 2, group F, member 2 isof... 218 7e-57
gi|5032173 nuclear receptor subfamily 2, group F, member 1 [Homo... 216 4e-56
gi|7657395 photoreceptor-specific nuclear receptor isoform b [Ho... 186 4e-47
gi|4507537 nuclear receptor subfamily 2, group E, member 1 [Homo... 184 2e-46
gi|238550159 estrogen-related receptor beta [Homo sapiens] 176 5e-44
gi|45545429 estrogen-related receptor gamma isoform 2 [Homo sapi... 173 2e-43
gi|45545427 estrogen-related receptor gamma isoform 2 [Homo sapi... 173 2e-43
gi|45545433 estrogen-related receptor gamma isoform 1 [Homo sapi... 173 2e-43
gi|197209821 estrogen-related receptor gamma isoform 2 [Homo sap... 173 2e-43
gi|14916494 retinoic acid receptor, beta isoform 1 [Homo sapiens] 162 4e-40
gi|7706515 photoreceptor-specific nuclear receptor isoform a [Ho... 157 2e-38
gi|112181200 retinoic acid receptor, gamma isoform 2 [Homo sapiens] 154 2e-37
gi|223718064 retinoic acid receptor, alpha isoform 1 [Homo sapiens] 153 3e-37
gi|4506419 retinoic acid receptor, alpha isoform 1 [Homo sapiens] 153 3e-37
gi|4506423 retinoic acid receptor, gamma isoform 1 [Homo sapiens] 153 3e-37
gi|67459914 retinoic acid receptor, alpha isoform 2 [Homo sapiens] 152 8e-37
gi|5453822 nuclear receptor subfamily 4, group A, member 2 [Homo... 148 1e-35
gi|27894344 nuclear receptor subfamily 4, group A, member 1 [Hom... 136 3e-32
gi|21361342 nuclear receptor subfamily 4, group A, member 1 [Hom... 136 3e-32
>gi|115583654 hepatocyte nuclear factor 4, gamma [Homo sapiens]
Length = 445
Score = 898 bits (2321), Expect = 0.0
Identities = 445/445 (100%), Positives = 445/445 (100%)
Query: 1 MDMANYSEVLDPTYTTLEFETMQILYNSSDSSAPETSMNTTDNGVNCLCAICGDRATGKH 60
MDMANYSEVLDPTYTTLEFETMQILYNSSDSSAPETSMNTTDNGVNCLCAICGDRATGKH
Sbjct: 1 MDMANYSEVLDPTYTTLEFETMQILYNSSDSSAPETSMNTTDNGVNCLCAICGDRATGKH 60
Query: 61 YGASSCDGCKGFFRRSIRKSHVYSCRFSRQCVVDKDKRNQCRYCRLRKCFRAGMKKEAVQ 120
YGASSCDGCKGFFRRSIRKSHVYSCRFSRQCVVDKDKRNQCRYCRLRKCFRAGMKKEAVQ
Sbjct: 61 YGASSCDGCKGFFRRSIRKSHVYSCRFSRQCVVDKDKRNQCRYCRLRKCFRAGMKKEAVQ 120
Query: 121 NERDRISTRRSTFDGSNIPSINTLAQAEVRSRQISVSSPGSSTDINVKKIASIGDVCESM 180
NERDRISTRRSTFDGSNIPSINTLAQAEVRSRQISVSSPGSSTDINVKKIASIGDVCESM
Sbjct: 121 NERDRISTRRSTFDGSNIPSINTLAQAEVRSRQISVSSPGSSTDINVKKIASIGDVCESM 180
Query: 181 KQQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMMYKDILLLGNNYVI 240
KQQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMMYKDILLLGNNYVI
Sbjct: 181 KQQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMMYKDILLLGNNYVI 240
Query: 241 HRNSCEVEISRVANRVLDELVRPFQEIQIDDNEYACLKAIVFFDPDAKGLSDPVKIKNMR 300
HRNSCEVEISRVANRVLDELVRPFQEIQIDDNEYACLKAIVFFDPDAKGLSDPVKIKNMR
Sbjct: 241 HRNSCEVEISRVANRVLDELVRPFQEIQIDDNEYACLKAIVFFDPDAKGLSDPVKIKNMR 300
Query: 301 FQVQIGLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFVKLFGMVKIDNLLQE 360
FQVQIGLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFVKLFGMVKIDNLLQE
Sbjct: 301 FQVQIGLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFVKLFGMVKIDNLLQE 360
Query: 361 MLLGGASNDGSHLHHPMHPHLSQDPLTGQTILLGPMSTLVHADQISTPETPLPSPPQGSG 420
MLLGGASNDGSHLHHPMHPHLSQDPLTGQTILLGPMSTLVHADQISTPETPLPSPPQGSG
Sbjct: 361 MLLGGASNDGSHLHHPMHPHLSQDPLTGQTILLGPMSTLVHADQISTPETPLPSPPQGSG 420
Query: 421 QEQYKIAANQASVISHQHLSKQKQL 445
QEQYKIAANQASVISHQHLSKQKQL
Sbjct: 421 QEQYKIAANQASVISHQHLSKQKQL 445
>gi|31077207 hepatocyte nuclear factor 4 alpha isoform a [Homo
sapiens]
Length = 464
Score = 651 bits (1680), Expect = 0.0
Identities = 322/437 (73%), Positives = 370/437 (84%), Gaps = 3/437 (0%)
Query: 1 MDMANYSEVLDPTYTTLEFETMQILYNSSDSSAPE-TSMNTTDN-GVNCLCAICGDRATG 58
MDMA+YS LDP YTTLEFE +Q+L +D+S E T++N ++ GV+ LCAICGDRATG
Sbjct: 10 MDMADYSAALDPAYTTLEFENVQVLTMGNDTSPSEGTNLNAPNSLGVSALCAICGDRATG 69
Query: 59 KHYGASSCDGCKGFFRRSIRKSHVYSCRFSRQCVVDKDKRNQCRYCRLRKCFRAGMKKEA 118
KHYGASSCDGCKGFFRRS+RK+H+YSCRFSRQCVVDKDKRNQCRYCRL+KCFRAGMKKEA
Sbjct: 70 KHYGASSCDGCKGFFRRSVRKNHMYSCRFSRQCVVDKDKRNQCRYCRLKKCFRAGMKKEA 129
Query: 119 VQNERDRISTRRSTFDGSNIPSINTLAQAEVRSRQISVSSPGSSTDINVKKIASIGDVCE 178
VQNERDRISTRRS+++ S++PSIN L QAEV SRQI+ G + DI KKIASI DVCE
Sbjct: 130 VQNERDRISTRRSSYEDSSLPSINALLQAEVLSRQITSPVSGINGDIRAKKIASIADVCE 189
Query: 179 SMKQQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMMYKDILLLGNNY 238
SMK+QLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSM++KD+LLLGN+Y
Sbjct: 190 SMKEQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMVFKDVLLLGNDY 249
Query: 239 VIHRNSCEV-EISRVANRVLDELVRPFQEIQIDDNEYACLKAIVFFDPDAKGLSDPVKIK 297
++ R+ E+ E+SRV+ R+LDELV PFQE+QIDDNEYA LKAI+FFDPDAKGLSDP KIK
Sbjct: 250 IVPRHCPELAEMSRVSIRILDELVLPFQELQIDDNEYAYLKAIIFFDPDAKGLSDPGKIK 309
Query: 298 NMRFQVQIGLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFVKLFGMVKIDNL 357
+R QVQ+ LEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQF+KLFGM KIDNL
Sbjct: 310 RLRSQVQVSLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFIKLFGMAKIDNL 369
Query: 358 LQEMLLGGASNDGSHLHHPMHPHLSQDPLTGQTILLGPMSTLVHADQISTPETPLPSPPQ 417
LQEMLLGG+ +D H HHP+HPHL Q+ + I+ M T + Q+STPETP PSPP
Sbjct: 370 LQEMLLGGSPSDAPHAHHPLHPHLMQEHMGTNVIVANTMPTHLSNGQMSTPETPQPSPPG 429
Query: 418 GSGQEQYKIAANQASVI 434
GSG E YK+ + I
Sbjct: 430 GSGSEPYKLLPGAVATI 446
>gi|31077205 hepatocyte nuclear factor 4 alpha isoform b [Homo
sapiens]
Length = 474
Score = 642 bits (1656), Expect = 0.0
Identities = 321/447 (71%), Positives = 370/447 (82%), Gaps = 13/447 (2%)
Query: 1 MDMANYSEVLDPTYTTLEFETMQILYNSSDSSAPE-TSMNTTDN-GVNCLCAICGDRATG 58
MDMA+YS LDP YTTLEFE +Q+L +D+S E T++N ++ GV+ LCAICGDRATG
Sbjct: 10 MDMADYSAALDPAYTTLEFENVQVLTMGNDTSPSEGTNLNAPNSLGVSALCAICGDRATG 69
Query: 59 KHYGASSCDGCKGFFRRSIRKSHVYSCRFSRQCVVDKDKRNQCRYCRLRKCFRAGMKKEA 118
KHYGASSCDGCKGFFRRS+RK+H+YSCRFSRQCVVDKDKRNQCRYCRL+KCFRAGMKKEA
Sbjct: 70 KHYGASSCDGCKGFFRRSVRKNHMYSCRFSRQCVVDKDKRNQCRYCRLKKCFRAGMKKEA 129
Query: 119 VQNERDRISTRRSTFDGSNIPSINTLAQAEVRSRQISVSSPGSSTDINVKKIASIGDVCE 178
VQNERDRISTRRS+++ S++PSIN L QAEV SRQI+ G + DI KKIASI DVCE
Sbjct: 130 VQNERDRISTRRSSYEDSSLPSINALLQAEVLSRQITSPVSGINGDIRAKKIASIADVCE 189
Query: 179 SMKQQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMMYKDILLLGNNY 238
SMK+QLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSM++KD+LLLGN+Y
Sbjct: 190 SMKEQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMVFKDVLLLGNDY 249
Query: 239 VIHRNSCEV-EISRVANRVLDELVRPFQEIQIDDNEYACLKAIVFFDPDAKGLSDPVKIK 297
++ R+ E+ E+SRV+ R+LDELV PFQE+QIDDNEYA LKAI+FFDPDAKGLSDP KIK
Sbjct: 250 IVPRHCPELAEMSRVSIRILDELVLPFQELQIDDNEYAYLKAIIFFDPDAKGLSDPGKIK 309
Query: 298 NMRFQVQIGLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFVKLFGMVKIDNL 357
+R QVQ+ LEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQF+KLFGM KIDNL
Sbjct: 310 RLRSQVQVSLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFIKLFGMAKIDNL 369
Query: 358 LQEMLLGGASNDGSHLHHPMHPHLSQDPLTGQTILLGPMSTLVHADQI----------ST 407
LQEMLLGG+ +D H HHP+HPHL Q+ + I+ M T + Q+ +T
Sbjct: 370 LQEMLLGGSPSDAPHAHHPLHPHLMQEHMGTNVIVANTMPTHLSNGQMCEWPRPRGQAAT 429
Query: 408 PETPLPSPPQGSGQEQYKIAANQASVI 434
PETP PSPP GSG E YK+ + I
Sbjct: 430 PETPQPSPPGGSGSEPYKLLPGAVATI 456
>gi|71725341 hepatocyte nuclear factor 4 alpha isoform e [Homo
sapiens]
Length = 442
Score = 616 bits (1588), Expect = e-176
Identities = 305/411 (74%), Positives = 350/411 (85%), Gaps = 3/411 (0%)
Query: 27 NSSDSSAPE-TSMNTTDN-GVNCLCAICGDRATGKHYGASSCDGCKGFFRRSIRKSHVYS 84
+S D+S E T++N ++ GV+ LCAICGDRATGKHYGASSCDGCKGFFRRS+RK+H+YS
Sbjct: 14 SSYDTSPSEGTNLNAPNSLGVSALCAICGDRATGKHYGASSCDGCKGFFRRSVRKNHMYS 73
Query: 85 CRFSRQCVVDKDKRNQCRYCRLRKCFRAGMKKEAVQNERDRISTRRSTFDGSNIPSINTL 144
CRFSRQCVVDKDKRNQCRYCRL+KCFRAGMKKEAVQNERDRISTRRS+++ S++PSIN L
Sbjct: 74 CRFSRQCVVDKDKRNQCRYCRLKKCFRAGMKKEAVQNERDRISTRRSSYEDSSLPSINAL 133
Query: 145 AQAEVRSRQISVSSPGSSTDINVKKIASIGDVCESMKQQLLVLVEWAKYIPAFCELPLDD 204
QAEV SRQI+ G + DI KKIASI DVCESMK+QLLVLVEWAKYIPAFCELPLDD
Sbjct: 134 LQAEVLSRQITSPVSGINGDIRAKKIASIADVCESMKEQLLVLVEWAKYIPAFCELPLDD 193
Query: 205 QVALLRAHAGEHLLLGATKRSMMYKDILLLGNNYVIHRNSCEV-EISRVANRVLDELVRP 263
QVALLRAHAGEHLLLGATKRSM++KD+LLLGN+Y++ R+ E+ E+SRV+ R+LDELV P
Sbjct: 194 QVALLRAHAGEHLLLGATKRSMVFKDVLLLGNDYIVPRHCPELAEMSRVSIRILDELVLP 253
Query: 264 FQEIQIDDNEYACLKAIVFFDPDAKGLSDPVKIKNMRFQVQIGLEDYINDRQYDSRGRFG 323
FQE+QIDDNEYA LKAI+FFDPDAKGLSDP KIK +R QVQ+ LEDYINDRQYDSRGRFG
Sbjct: 254 FQELQIDDNEYAYLKAIIFFDPDAKGLSDPGKIKRLRSQVQVSLEDYINDRQYDSRGRFG 313
Query: 324 ELLLLLPTLQSITWQMIEQIQFVKLFGMVKIDNLLQEMLLGGASNDGSHLHHPMHPHLSQ 383
ELLLLLPTLQSITWQMIEQIQF+KLFGM KIDNLLQEMLLGG+ +D H HHP+HPHL Q
Sbjct: 314 ELLLLLPTLQSITWQMIEQIQFIKLFGMAKIDNLLQEMLLGGSPSDAPHAHHPLHPHLMQ 373
Query: 384 DPLTGQTILLGPMSTLVHADQISTPETPLPSPPQGSGQEQYKIAANQASVI 434
+ + I+ M T + Q+STPETP PSPP GSG E YK+ + I
Sbjct: 374 EHMGTNVIVANTMPTHLSNGQMSTPETPQPSPPGGSGSEPYKLLPGAVATI 424
>gi|71725339 hepatocyte nuclear factor 4 alpha isoform d [Homo
sapiens]
Length = 452
Score = 607 bits (1564), Expect = e-174
Identities = 304/421 (72%), Positives = 350/421 (83%), Gaps = 13/421 (3%)
Query: 27 NSSDSSAPE-TSMNTTDN-GVNCLCAICGDRATGKHYGASSCDGCKGFFRRSIRKSHVYS 84
+S D+S E T++N ++ GV+ LCAICGDRATGKHYGASSCDGCKGFFRRS+RK+H+YS
Sbjct: 14 SSYDTSPSEGTNLNAPNSLGVSALCAICGDRATGKHYGASSCDGCKGFFRRSVRKNHMYS 73
Query: 85 CRFSRQCVVDKDKRNQCRYCRLRKCFRAGMKKEAVQNERDRISTRRSTFDGSNIPSINTL 144
CRFSRQCVVDKDKRNQCRYCRL+KCFRAGMKKEAVQNERDRISTRRS+++ S++PSIN L
Sbjct: 74 CRFSRQCVVDKDKRNQCRYCRLKKCFRAGMKKEAVQNERDRISTRRSSYEDSSLPSINAL 133
Query: 145 AQAEVRSRQISVSSPGSSTDINVKKIASIGDVCESMKQQLLVLVEWAKYIPAFCELPLDD 204
QAEV SRQI+ G + DI KKIASI DVCESMK+QLLVLVEWAKYIPAFCELPLDD
Sbjct: 134 LQAEVLSRQITSPVSGINGDIRAKKIASIADVCESMKEQLLVLVEWAKYIPAFCELPLDD 193
Query: 205 QVALLRAHAGEHLLLGATKRSMMYKDILLLGNNYVIHRNSCEV-EISRVANRVLDELVRP 263
QVALLRAHAGEHLLLGATKRSM++KD+LLLGN+Y++ R+ E+ E+SRV+ R+LDELV P
Sbjct: 194 QVALLRAHAGEHLLLGATKRSMVFKDVLLLGNDYIVPRHCPELAEMSRVSIRILDELVLP 253
Query: 264 FQEIQIDDNEYACLKAIVFFDPDAKGLSDPVKIKNMRFQVQIGLEDYINDRQYDSRGRFG 323
FQE+QIDDNEYA LKAI+FFDPDAKGLSDP KIK +R QVQ+ LEDYINDRQYDSRGRFG
Sbjct: 254 FQELQIDDNEYAYLKAIIFFDPDAKGLSDPGKIKRLRSQVQVSLEDYINDRQYDSRGRFG 313
Query: 324 ELLLLLPTLQSITWQMIEQIQFVKLFGMVKIDNLLQEMLLGGASNDGSHLHHPMHPHLSQ 383
ELLLLLPTLQSITWQMIEQIQF+KLFGM KIDNLLQEMLLGG+ +D H HHP+HPHL Q
Sbjct: 314 ELLLLLPTLQSITWQMIEQIQFIKLFGMAKIDNLLQEMLLGGSPSDAPHAHHPLHPHLMQ 373
Query: 384 DPLTGQTILLGPMSTLVHADQI----------STPETPLPSPPQGSGQEQYKIAANQASV 433
+ + I+ M T + Q+ +TPETP PSPP GSG E YK+ +
Sbjct: 374 EHMGTNVIVANTMPTHLSNGQMCEWPRPRGQAATPETPQPSPPGGSGSEPYKLLPGAVAT 433
Query: 434 I 434
I
Sbjct: 434 I 434
>gi|31077209 hepatocyte nuclear factor 4 alpha isoform c [Homo
sapiens]
Length = 417
Score = 586 bits (1511), Expect = e-167
Identities = 291/368 (79%), Positives = 329/368 (89%), Gaps = 3/368 (0%)
Query: 1 MDMANYSEVLDPTYTTLEFETMQILYNSSDSSAPE-TSMNTTDN-GVNCLCAICGDRATG 58
MDMA+YS LDP YTTLEFE +Q+L +D+S E T++N ++ GV+ LCAICGDRATG
Sbjct: 10 MDMADYSAALDPAYTTLEFENVQVLTMGNDTSPSEGTNLNAPNSLGVSALCAICGDRATG 69
Query: 59 KHYGASSCDGCKGFFRRSIRKSHVYSCRFSRQCVVDKDKRNQCRYCRLRKCFRAGMKKEA 118
KHYGASSCDGCKGFFRRS+RK+H+YSCRFSRQCVVDKDKRNQCRYCRL+KCFRAGMKKEA
Sbjct: 70 KHYGASSCDGCKGFFRRSVRKNHMYSCRFSRQCVVDKDKRNQCRYCRLKKCFRAGMKKEA 129
Query: 119 VQNERDRISTRRSTFDGSNIPSINTLAQAEVRSRQISVSSPGSSTDINVKKIASIGDVCE 178
VQNERDRISTRRS+++ S++PSIN L QAEV SRQI+ G + DI KKIASI DVCE
Sbjct: 130 VQNERDRISTRRSSYEDSSLPSINALLQAEVLSRQITSPVSGINGDIRAKKIASIADVCE 189
Query: 179 SMKQQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMMYKDILLLGNNY 238
SMK+QLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSM++KD+LLLGN+Y
Sbjct: 190 SMKEQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMVFKDVLLLGNDY 249
Query: 239 VIHRNSCEV-EISRVANRVLDELVRPFQEIQIDDNEYACLKAIVFFDPDAKGLSDPVKIK 297
++ R+ E+ E+SRV+ R+LDELV PFQE+QIDDNEYA LKAI+FFDPDAKGLSDP KIK
Sbjct: 250 IVPRHCPELAEMSRVSIRILDELVLPFQELQIDDNEYAYLKAIIFFDPDAKGLSDPGKIK 309
Query: 298 NMRFQVQIGLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFVKLFGMVKIDNL 357
+R QVQ+ LEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQF+KLFGM KIDNL
Sbjct: 310 RLRSQVQVSLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFIKLFGMAKIDNL 369
Query: 358 LQEMLLGG 365
LQEMLLGG
Sbjct: 370 LQEMLLGG 377
>gi|71725336 hepatocyte nuclear factor 4 alpha isoform f [Homo
sapiens]
Length = 395
Score = 551 bits (1419), Expect = e-157
Identities = 274/342 (80%), Positives = 309/342 (90%), Gaps = 3/342 (0%)
Query: 27 NSSDSSAPE-TSMNTTDN-GVNCLCAICGDRATGKHYGASSCDGCKGFFRRSIRKSHVYS 84
+S D+S E T++N ++ GV+ LCAICGDRATGKHYGASSCDGCKGFFRRS+RK+H+YS
Sbjct: 14 SSYDTSPSEGTNLNAPNSLGVSALCAICGDRATGKHYGASSCDGCKGFFRRSVRKNHMYS 73
Query: 85 CRFSRQCVVDKDKRNQCRYCRLRKCFRAGMKKEAVQNERDRISTRRSTFDGSNIPSINTL 144
CRFSRQCVVDKDKRNQCRYCRL+KCFRAGMKKEAVQNERDRISTRRS+++ S++PSIN L
Sbjct: 74 CRFSRQCVVDKDKRNQCRYCRLKKCFRAGMKKEAVQNERDRISTRRSSYEDSSLPSINAL 133
Query: 145 AQAEVRSRQISVSSPGSSTDINVKKIASIGDVCESMKQQLLVLVEWAKYIPAFCELPLDD 204
QAEV SRQI+ G + DI KKIASI DVCESMK+QLLVLVEWAKYIPAFCELPLDD
Sbjct: 134 LQAEVLSRQITSPVSGINGDIRAKKIASIADVCESMKEQLLVLVEWAKYIPAFCELPLDD 193
Query: 205 QVALLRAHAGEHLLLGATKRSMMYKDILLLGNNYVIHRNSCEV-EISRVANRVLDELVRP 263
QVALLRAHAGEHLLLGATKRSM++KD+LLLGN+Y++ R+ E+ E+SRV+ R+LDELV P
Sbjct: 194 QVALLRAHAGEHLLLGATKRSMVFKDVLLLGNDYIVPRHCPELAEMSRVSIRILDELVLP 253
Query: 264 FQEIQIDDNEYACLKAIVFFDPDAKGLSDPVKIKNMRFQVQIGLEDYINDRQYDSRGRFG 323
FQE+QIDDNEYA LKAI+FFDPDAKGLSDP KIK +R QVQ+ LEDYINDRQYDSRGRFG
Sbjct: 254 FQELQIDDNEYAYLKAIIFFDPDAKGLSDPGKIKRLRSQVQVSLEDYINDRQYDSRGRFG 313
Query: 324 ELLLLLPTLQSITWQMIEQIQFVKLFGMVKIDNLLQEMLLGG 365
ELLLLLPTLQSITWQMIEQIQF+KLFGM KIDNLLQEMLLGG
Sbjct: 314 ELLLLLPTLQSITWQMIEQIQFIKLFGMAKIDNLLQEMLLGG 355
>gi|11415052 retinoid X receptor, beta [Homo sapiens]
Length = 533
Score = 268 bits (684), Expect = 1e-71
Identities = 142/324 (43%), Positives = 201/324 (62%), Gaps = 10/324 (3%)
Query: 48 LCAICGDRATGKHYGASSCDGCKGFFRRSIRKSHVYSCRFSRQCVVDKDKRNQCRYCRLR 107
LCAICGDR++GKHYG SC+GCKGFF+R+IRK YSCR ++ C VDK +RN+C+YCR +
Sbjct: 204 LCAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLTYSCRDNKDCTVDKRQRNRCQYCRYQ 263
Query: 108 KCFRAGMKKEAVQNERDRISTRRSTFDGS-----NIPSINTLAQAEVRSRQIS---VSSP 159
KC GMK+EAVQ ER R + +G+ +P ++ + +AE+ Q S V P
Sbjct: 264 KCLATGMKREAVQEERQRGKDKDGDGEGAGGAPEEMP-VDRILEAELAVEQKSDQGVEGP 322
Query: 160 GSSTDINVKKIASIGDVCESMKQQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLL 219
G + + ++C++ +QL LVEWAK IP F LPLDDQV LLRA E L+
Sbjct: 323 GGTGGSGSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSSLPLDDQVILLRAGWNELLIA 382
Query: 220 GATKRSMMYKDILLLGNNYVIHRNSC-EVEISRVANRVLDELVRPFQEIQIDDNEYACLK 278
+ RS+ +D +LL +HRNS + + +RVL ELV +++++D E CL+
Sbjct: 383 SFSHRSIDVRDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMRMDKTELGCLR 442
Query: 279 AIVFFDPDAKGLSDPVKIKNMRFQVQIGLEDYINDRQYDSRGRFGELLLLLPTLQSITWQ 338
AI+ F+PDAKGLS+P +++ +R +V LE Y + + +GRF +LLL LP L+SI +
Sbjct: 443 AIILFNPDAKGLSNPSEVEVLREKVYASLETYCKQKYPEQQGRFAKLLLRLPALRSIGLK 502
Query: 339 MIEQIQFVKLFGMVKIDNLLQEML 362
+E + F KL G ID L EML
Sbjct: 503 CLEHLFFFKLIGDTPIDTFLMEML 526
>gi|4506755 retinoid X receptor, alpha [Homo sapiens]
Length = 462
Score = 264 bits (675), Expect = 1e-70
Identities = 138/322 (42%), Positives = 199/322 (61%), Gaps = 7/322 (2%)
Query: 48 LCAICGDRATGKHYGASSCDGCKGFFRRSIRKSHVYSCRFSRQCVVDKDKRNQCRYCRLR 107
+CAICGDR++GKHYG SC+GCKGFF+R++RK Y+CR ++ C++DK +RN+C+YCR +
Sbjct: 134 ICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQ 193
Query: 108 KCFRAGMKKEAVQNERDRISTR-----RSTFDGSNIPSINTLAQAEVRSRQISVSSPGSS 162
KC GMK+EAVQ ER R R ST + + + +AE+ + + ++
Sbjct: 194 KCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEAN 253
Query: 163 TDINVKKIAS-IGDVCESMKQQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGA 221
+N + ++C++ +QL LVEWAK IP F ELPLDDQV LLRA E L+
Sbjct: 254 MGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASF 313
Query: 222 TKRSMMYKDILLLGNNYVIHRNSC-EVEISRVANRVLDELVRPFQEIQIDDNEYACLKAI 280
+ RS+ KD +LL +HRNS + + +RVL ELV +++Q+D E CL+AI
Sbjct: 314 SHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAI 373
Query: 281 VFFDPDAKGLSDPVKIKNMRFQVQIGLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMI 340
V F+PD+KGLS+P +++ +R +V LE Y + + GRF +LLL LP L+SI + +
Sbjct: 374 VLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCL 433
Query: 341 EQIQFVKLFGMVKIDNLLQEML 362
E + F KL G ID L EML
Sbjct: 434 EHLFFFKLIGDTPIDTFLMEML 455
>gi|5902068 retinoid X receptor, gamma isoform a [Homo sapiens]
Length = 463
Score = 257 bits (657), Expect = 1e-68
Identities = 135/322 (41%), Positives = 199/322 (61%), Gaps = 4/322 (1%)
Query: 45 VNCLCAICGDRATGKHYGASSCDGCKGFFRRSIRKSHVYSCRFSRQCVVDKDKRNQCRYC 104
V +CAICGDR++GKHYG SC+GCKGFF+R+IRK +Y+CR ++ C++DK +RN+C+YC
Sbjct: 135 VKHICAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLIYTCRDNKDCLIDKRQRNRCQYC 194
Query: 105 RLRKCFRAGMKKEAVQNERDRISTRRSTFDGSNIPSINTLAQAEVRSRQISVSSPGSS-T 163
R +KC GMK+EAVQ ER R R + + + +++V S
Sbjct: 195 RYQKCLVMGMKREAVQEERQRSRERAESEAECATSGHEDMPVERILEAELAVEPKTESYG 254
Query: 164 DINVKKIAS--IGDVCESMKQQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGA 221
D+N++ + + ++C + +QL LVEWAK IP F +L L+DQV LLRA E L+
Sbjct: 255 DMNMENSTNDPVTNICHAADKQLFTLVEWAKRIPHFSDLTLEDQVILLRAGWNELLIASF 314
Query: 222 TKRSMMYKDILLLGNNYVIHRNSC-EVEISRVANRVLDELVRPFQEIQIDDNEYACLKAI 280
+ RS+ +D +LL +HR+S + + +RVL ELV +++Q+D +E CL+AI
Sbjct: 315 SHRSVSVQDGILLATGLHVHRSSAHSAGVGSIFDRVLTELVSKMKDMQMDKSELGCLRAI 374
Query: 281 VFFDPDAKGLSDPVKIKNMRFQVQIGLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMI 340
V F+PDAKGLS+P +++ +R +V LE Y + + GRF +LLL LP L+SI + +
Sbjct: 375 VLFNPDAKGLSNPSEVETLREKVYATLEAYTKQKYPEQPGRFAKLLLRLPALRSIGLKCL 434
Query: 341 EQIQFVKLFGMVKIDNLLQEML 362
E + F KL G ID L EML
Sbjct: 435 EHLFFFKLIGDTPIDTFLMEML 456
>gi|20070199 nuclear receptor subfamily 2, group F, member 6 [Homo
sapiens]
Length = 404
Score = 219 bits (558), Expect = 4e-57
Identities = 125/346 (36%), Positives = 188/346 (54%), Gaps = 23/346 (6%)
Query: 44 GVNCLCAICGDRATGKHYGASSCDGCKGFFRRSIRKSHVYSCRFSRQCVVDKDKRNQCRY 103
G+ C +CGD+++GKHYG +C+GCK FF+RSIR++ Y+CR +R C +D+ RNQC+Y
Sbjct: 51 GLQVDCVVCGDKSSGKHYGVFTCEGCKSFFKRSIRRNLSYTCRSNRDCQIDQHHRNQCQY 110
Query: 104 CRLRKCFRAGMKKEAVQNERDRISTRRSTFDGSNIPSINTLAQAEVRSRQISVSSPGSST 163
CRL+KCFR GM+KEAVQ R S + S P + LA A + P S
Sbjct: 111 CRLKKCFRVGMRKEAVQRGRIPHSLPGAVAASSGSPPGSALA-AVASGGDLFPGQPVSEL 169
Query: 164 DINVKK--------------------IASIGDVCESMKQQLLVLVEWAKYIPAFCELPLD 203
+ + + I +VCE + L VEWA++ P F ELP+
Sbjct: 170 IAQLLRAEPYPAAAGRFGAGGGAAGAVLGIDNVCELAARLLFSTVEWARHAPFFPELPVA 229
Query: 204 DQVALLRAHAGEHLLLGATKRSM-MYKDILLLGNNYVIHRNSCEVEISRVAN-RVLDELV 261
DQVALLR E +L A + ++ ++ LL + E ++ + R E V
Sbjct: 230 DQVALLRLSWSELFVLNAAQAALPLHTAPLLAAAGLHAAPMAAERAVAFMDQVRAFQEQV 289
Query: 262 RPFQEIQIDDNEYACLKAIVFFDPDAKGLSDPVKIKNMRFQVQIGLEDYINDRQYDSRGR 321
+Q+D EY CLKAI F PDA GLSDP +++++ + Q+ L +Y+ + R
Sbjct: 290 DKLGRLQVDSAEYGCLKAIALFTPDACGLSDPAHVESLQEKAQVALTEYVRAQYPSQPQR 349
Query: 322 FGELLLLLPTLQSITWQMIEQIQFVKLFGMVKIDNLLQEMLLGGAS 367
FG LLL LP L+++ +I Q+ F++L G I+ L+++MLL G++
Sbjct: 350 FGRLLLRLPALRAVPASLISQLFFMRLVGKTPIETLIRDMLLSGST 395
>gi|14149746 nuclear receptor subfamily 2, group F, member 2 isoform
a [Homo sapiens]
Length = 414
Score = 218 bits (556), Expect = 7e-57
Identities = 123/329 (37%), Positives = 194/329 (58%), Gaps = 12/329 (3%)
Query: 49 CAICGDRATGKHYGASSCDGCKGFFRRSIRKSHVYSCRFSRQCVVDKDKRNQCRYCRLRK 108
C +CGD+++GKHYG +C+GCK FF+RS+R++ Y+CR +R C +D+ RNQC+YCRL+K
Sbjct: 79 CVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLSYTCRANRNCPIDQHHRNQCQYCRLKK 138
Query: 109 CFRAGMKKEAVQNERDRISTRRSTFDGSNIPSINTLAQAEVRSRQISV--------SSPG 160
C + GM++EAVQ R R+ + T + + + L S IS+ +S
Sbjct: 139 CLKVGMRREAVQ--RGRMPPTQPTHGQFALTNGDPLNCHSYLSGYISLLLRAEPYPTSRF 196
Query: 161 SSTDINVKKIASIGDVCESMKQQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLG 220
S + I I ++CE + L VEWA+ IP F +L + DQVALLR E +L
Sbjct: 197 GSQCMQPNNIMGIENICELAARMLFSAVEWARNIPFFPDLQITDQVALLRLTWSELFVLN 256
Query: 221 ATKRSM-MYKDILLLGNNYVIHRNSCEVEISRVAN-RVLDELVRPFQEIQIDDNEYACLK 278
A + SM ++ LL S + ++ + + R+ E V + + +D EY+CLK
Sbjct: 257 AAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLK 316
Query: 279 AIVFFDPDAKGLSDPVKIKNMRFQVQIGLEDYINDRQYDSRGRFGELLLLLPTLQSITWQ 338
AIV F DA GLSD +++++ + Q LE+Y+ + + RFG+LLL LP+L++++
Sbjct: 317 AIVLFTSDACGLSDVAHVESLQEKSQCALEEYVRSQYPNQPTRFGKLLLRLPSLRTVSSS 376
Query: 339 MIEQIQFVKLFGMVKIDNLLQEMLLGGAS 367
+IEQ+ FV+L G I+ L+++MLL G+S
Sbjct: 377 VIEQLFFVRLVGKTPIETLIRDMLLSGSS 405
>gi|5032173 nuclear receptor subfamily 2, group F, member 1 [Homo
sapiens]
Length = 423
Score = 216 bits (549), Expect = 4e-56
Identities = 124/332 (37%), Positives = 192/332 (57%), Gaps = 18/332 (5%)
Query: 49 CAICGDRATGKHYGASSCDGCKGFFRRSIRKSHVYSCRFSRQCVVDKDKRNQCRYCRLRK 108
C +CGD+++GKHYG +C+GCK FF+RS+R++ Y+CR +R C +D+ RNQC+YCRL+K
Sbjct: 86 CVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLTYTCRANRNCPIDQHHRNQCQYCRLKK 145
Query: 109 CFRAGMKKEAVQ---------NERDRISTRRSTFDGSNIPS--INTLAQAEVRSRQISVS 157
C + GM++EAVQ N T +G S I+ L +AE +
Sbjct: 146 CLKVGMRREAVQRGRMPPTQPNPGQYALTNGDPLNGHCYLSGYISLLLRAEPYP-----T 200
Query: 158 SPGSSTDINVKKIASIGDVCESMKQQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHL 217
S S + I I ++CE + L VEWA+ IP F +L + DQV+LLR E
Sbjct: 201 SRYGSQCMQPNNIMGIENICELAARLLFSAVEWARNIPFFPDLQITDQVSLLRLTWSELF 260
Query: 218 LLGATKRSM-MYKDILLLGNNYVIHRNSCEVEISRVAN-RVLDELVRPFQEIQIDDNEYA 275
+L A + SM ++ LL S + ++ + + R+ E V + + +D EY+
Sbjct: 261 VLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYS 320
Query: 276 CLKAIVFFDPDAKGLSDPVKIKNMRFQVQIGLEDYINDRQYDSRGRFGELLLLLPTLQSI 335
CLKAIV F DA GLSD I++++ + Q LE+Y+ + + RFG+LLL LP+L+++
Sbjct: 321 CLKAIVLFTSDACGLSDAAHIESLQEKSQCALEEYVRSQYPNQPSRFGKLLLRLPSLRTV 380
Query: 336 TWQMIEQIQFVKLFGMVKIDNLLQEMLLGGAS 367
+ +IEQ+ FV+L G I+ L+++MLL G+S
Sbjct: 381 SSSVIEQLFFVRLVGKTPIETLIRDMLLSGSS 412
>gi|7657395 photoreceptor-specific nuclear receptor isoform b [Homo
sapiens]
Length = 410
Score = 186 bits (472), Expect = 4e-47
Identities = 113/361 (31%), Positives = 176/361 (48%), Gaps = 48/361 (13%)
Query: 49 CAICGDRATGKHYGASSCDGCKGFFRRSIRKSHVYSCRFSR-QCVVDKDKRNQCRYCRLR 107
C +CGD ++GKHYG +C+GC GFF+RS+R+ +Y C+ C VDK RNQC+ CRL+
Sbjct: 47 CRVCGDSSSGKHYGIYACNGCSGFFKRSVRRRLIYRCQVGAGMCPVDKAHRNQCQACRLK 106
Query: 108 KCFRAGMKKEAVQNERDRISTRRSTFDG-------------------------------- 135
KC +AGM ++AVQNER ST + D
Sbjct: 107 KCLQAGMNQDAVQNERQPRSTAQVHLDSMESNTESRPESLVAPPAPAGRSPRGPTPMSAA 166
Query: 136 --------SNIPSINTLAQAEVRSRQISVSSPGSSTDINVKKIAS-----IGDVCESMKQ 182
+++ + T A+ E ++ + + +S + + E+ +
Sbjct: 167 RALGHHFMASLITAETCAKLEPEDADENIDVTSNDPEFPSSPYSSSSPCGLDSIHETSAR 226
Query: 183 QLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMMYKDILLLGNNYVIHR 242
L + V+WAK +P F LP DQV LL E LLGA + S+ LL
Sbjct: 227 LLFMAVKWAKNLPVFSSLPFRDQVILLEEAWSELFLLGAIQWSLPLDSCPLLAPPEASAA 286
Query: 243 NSCE--VEISRVANRVLDELVRPFQEIQIDDNEYACLKAIVFFDPDAKGLSDPVKIKNMR 300
+ + ++ + RVL E + F+ + +D E+AC+KA+V F P+ +GL DP ++ ++
Sbjct: 287 GGAQGRLTLASMETRVLQETISRFRALAVDPTEFACMKALVLFKPETRGLKDPEHVEALQ 346
Query: 301 FQVQIGLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFVKLFGMVKIDNLLQE 360
Q Q+ L + RFG+LLLLLP+L+ IT + IE + F K G ++ LL +
Sbjct: 347 DQSQVMLSQHSKAHHPSQPVRFGKLLLLLPSLRFITAERIELLFFRKTIGNTPMEKLLCD 406
Query: 361 M 361
M
Sbjct: 407 M 407
>gi|4507537 nuclear receptor subfamily 2, group E, member 1 [Homo
sapiens]
Length = 385
Score = 184 bits (466), Expect = 2e-46
Identities = 120/365 (32%), Positives = 188/365 (51%), Gaps = 53/365 (14%)
Query: 49 CAICGDRATGKHYGASSCDGCKGFFRRSIRKSHVYSCRFSRQ--CVVDKDKRNQCRYCRL 106
C +CGDR++GKHYG +CDGC GFF+RSIR++ Y C+ Q C VDK RNQCR CRL
Sbjct: 16 CKVCGDRSSGKHYGVYACDGCSGFFKRSIRRNRTYVCKSGNQGGCPVDKTHRNQCRACRL 75
Query: 107 RKCFRAGMKKEAVQNER-DRISTRR-----------------STFDGSNIPS-------- 140
+KC M K+AVQ+ER R ST R + F + +P+
Sbjct: 76 KKCLEVNMNKDAVQHERGPRTSTIRKQVALYFRGHKEENGAAAHFPSAALPAPAFFTAVT 135
Query: 141 --------INTLAQAEVRSRQISVSSPG-------SSTDINVKKIASIGDVCESMKQQLL 185
+ ++ R +S++ P + T + + ++A+ VCES + L
Sbjct: 136 QLEPHGLELAAVSTTPERQTLVSLAQPTPKYPHEVNGTPMYLYEVAT-ESVCESAARLLF 194
Query: 186 VLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMMYKDILLLGNNYVIHRNSC 245
+ ++WAK +PAF L L DQ+ LL E +LG + ++ LL + + N+
Sbjct: 195 MSIKWAKSVPAFSTLSLQDQLMLLEDAWRELFVLGIAQWAIPVDANTLLAVSGMNGDNTD 254
Query: 246 EVEISRVANRV--LDELVRPFQEIQIDDNEYACLKAIVFF-------DPDAKGLSDPVKI 296
+++++ + + L E+V F+++++D E+ACLK IV F + + + I
Sbjct: 255 SQKLNKIISEIQALQEVVARFRQLRLDATEFACLKCIVTFKAVPTHSGSELRSFRNAAAI 314
Query: 297 KNMRFQVQIGLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFVKLFGMVKIDN 356
++ + Q+ L YI+ R RFG+LLLLLP L+SI+ IE++ F K G V I
Sbjct: 315 AALQDEAQLTLNSYIHTRYPTQPCRFGKLLLLLPALRSISPSTIEEVFFKKTIGNVPITR 374
Query: 357 LLQEM 361
LL +M
Sbjct: 375 LLSDM 379
>gi|238550159 estrogen-related receptor beta [Homo sapiens]
Length = 508
Score = 176 bits (445), Expect = 5e-44
Identities = 108/387 (27%), Positives = 190/387 (49%), Gaps = 30/387 (7%)
Query: 48 LCAICGDRATGKHYGASSCDGCKGFFRRSIRKSHVYSCRFSRQCVVDKDKRNQCRYCRLR 107
LC +CGD A+G HYG +SC+ CK FF+R+I+ + YSC + +C + K +R C+ CR
Sbjct: 102 LCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFM 161
Query: 108 KCFRAGMKKEAVQNERDRISTR--RSTFDGSNIPSINTLAQAEVRSRQISVSS------- 158
KC + GM KE V+ +R R + + D + P ++ + + S
Sbjct: 162 KCLKVGMLKEGVRLDRVRGGRQKYKRRLDSESSPYLSLQISPPAKKPLTKIVSYLLVAEP 221
Query: 159 -------PGSSTDINVKKIASIGDVCESMKQQLLVLVEWAKYIPAFCELPLDDQVALLRA 211
P + ++K + ++ C+ ++L+V++ WAK+IP F L L DQ++LL++
Sbjct: 222 DKLYAMPPPGMPEGDIKALTTL---CDLADRELVVIIGWAKHIPGFSSLSLGDQMSLLQS 278
Query: 212 HAGEHLLLGATKRSMMYKDILLLGNNYVIHRNSCEVEISRVANRVLDELVRPFQEIQIDD 271
E L+LG RS+ Y D L+ +Y++ + R + +LVR +++++++
Sbjct: 279 AWMEILILGIVYRSLPYDDKLVYAEDYIMDEEHSRLAGLLELYRAILQLVRRYKKLKVEK 338
Query: 272 NEYACLKAIVFFDPDAKGLSDPVKIKNMRFQVQIGLEDYINDRQYDSRGRFGELLLLLPT 331
E+ LKA+ + D+ + D ++ ++ + L+DY ++++ R G+LLL LP
Sbjct: 339 EEFVTLKALALANSDSMYIEDLEAVQKLQDLLHEALQDYELSQRHEEPWRTGKLLLTLPL 398
Query: 332 LQSITWQMIEQIQFVKLFGMVKIDNLLQEML---LGGASNDGSHLHHPMHPHLSQDPLTG 388
L+ + ++ VKL G V + L EML +G GS M H + P
Sbjct: 399 LRQTAAKAVQHFYSVKLQGKVPMHKLFLEMLEAKVGQEQLRGSPKDERMSSHDGKCPFQS 458
Query: 389 QTILLGPMSTLVHADQISTPETPLPSP 415
+ DQ ++P P P P
Sbjct: 459 --------AAFTSRDQSNSPGIPNPRP 477
>gi|45545429 estrogen-related receptor gamma isoform 2 [Homo
sapiens]
Length = 435
Score = 173 bits (439), Expect = 2e-43
Identities = 99/355 (27%), Positives = 183/355 (51%), Gaps = 17/355 (4%)
Query: 25 LYNSSDSSAPETSMNTTDNGVNC----LCAICGDRATGKHYGASSCDGCKGFFRRSIRKS 80
LY+ S+ E + +N LC +CGD A+G HYG +SC+ CK FF+R+I+ +
Sbjct: 77 LYDDCSSTIVEDPQTKCEYMLNSMPKRLCLVCGDIASGYHYGVASCEACKAFFKRTIQGN 136
Query: 81 HVYSCRFSRQCVVDKDKRNQCRYCRLRKCFRAGMKKEAVQNERDRISTRR--STFDGSNI 138
YSC + +C + K +R C+ CR KC + GM KE V+ +R R ++ D N
Sbjct: 137 IEYSCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRVRGGRQKYKRRIDAENS 196
Query: 139 PSINTLAQAEVRS------RQISVSSPGS-----STDINVKKIASIGDVCESMKQQLLVL 187
P +N + + V+ P + I ++ +C+ ++L+V+
Sbjct: 197 PYLNPQLVQPAKKPYNKIVSHLLVAEPEKIYAMPDPTVPDSDIKALTTLCDLADRELVVI 256
Query: 188 VEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMMYKDILLLGNNYVIHRNSCEV 247
+ WAK+IP F L L DQ++LL++ E L+LG RS+ ++D L+ ++Y++ + ++
Sbjct: 257 IGWAKHIPGFSTLSLADQMSLLQSAWMEILILGVVYRSLSFEDELVYADDYIMDEDQSKL 316
Query: 248 EISRVANRVLDELVRPFQEIQIDDNEYACLKAIVFFDPDAKGLSDPVKIKNMRFQVQIGL 307
N + +LV+ ++ ++++ E+ LKAI + D+ + D ++ ++ + L
Sbjct: 317 AGLLDLNNAILQLVKKYKSMKLEKEEFVTLKAIALANSDSMHIEDVEAVQKLQDVLHEAL 376
Query: 308 EDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFVKLFGMVKIDNLLQEML 362
+DY + + R G++L+ LP L+ + + ++ +KL G V + L EML
Sbjct: 377 QDYEAGQHMEDPRRAGKMLMTLPLLRQTSTKAVQHFYNIKLEGKVPMHKLFLEML 431
>gi|45545427 estrogen-related receptor gamma isoform 2 [Homo
sapiens]
Length = 435
Score = 173 bits (439), Expect = 2e-43
Identities = 99/355 (27%), Positives = 183/355 (51%), Gaps = 17/355 (4%)
Query: 25 LYNSSDSSAPETSMNTTDNGVNC----LCAICGDRATGKHYGASSCDGCKGFFRRSIRKS 80
LY+ S+ E + +N LC +CGD A+G HYG +SC+ CK FF+R+I+ +
Sbjct: 77 LYDDCSSTIVEDPQTKCEYMLNSMPKRLCLVCGDIASGYHYGVASCEACKAFFKRTIQGN 136
Query: 81 HVYSCRFSRQCVVDKDKRNQCRYCRLRKCFRAGMKKEAVQNERDRISTRR--STFDGSNI 138
YSC + +C + K +R C+ CR KC + GM KE V+ +R R ++ D N
Sbjct: 137 IEYSCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRVRGGRQKYKRRIDAENS 196
Query: 139 PSINTLAQAEVRS------RQISVSSPGS-----STDINVKKIASIGDVCESMKQQLLVL 187
P +N + + V+ P + I ++ +C+ ++L+V+
Sbjct: 197 PYLNPQLVQPAKKPYNKIVSHLLVAEPEKIYAMPDPTVPDSDIKALTTLCDLADRELVVI 256
Query: 188 VEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMMYKDILLLGNNYVIHRNSCEV 247
+ WAK+IP F L L DQ++LL++ E L+LG RS+ ++D L+ ++Y++ + ++
Sbjct: 257 IGWAKHIPGFSTLSLADQMSLLQSAWMEILILGVVYRSLSFEDELVYADDYIMDEDQSKL 316
Query: 248 EISRVANRVLDELVRPFQEIQIDDNEYACLKAIVFFDPDAKGLSDPVKIKNMRFQVQIGL 307
N + +LV+ ++ ++++ E+ LKAI + D+ + D ++ ++ + L
Sbjct: 317 AGLLDLNNAILQLVKKYKSMKLEKEEFVTLKAIALANSDSMHIEDVEAVQKLQDVLHEAL 376
Query: 308 EDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFVKLFGMVKIDNLLQEML 362
+DY + + R G++L+ LP L+ + + ++ +KL G V + L EML
Sbjct: 377 QDYEAGQHMEDPRRAGKMLMTLPLLRQTSTKAVQHFYNIKLEGKVPMHKLFLEML 431
>gi|45545433 estrogen-related receptor gamma isoform 1 [Homo
sapiens]
Length = 458
Score = 173 bits (439), Expect = 2e-43
Identities = 99/355 (27%), Positives = 183/355 (51%), Gaps = 17/355 (4%)
Query: 25 LYNSSDSSAPETSMNTTDNGVNC----LCAICGDRATGKHYGASSCDGCKGFFRRSIRKS 80
LY+ S+ E + +N LC +CGD A+G HYG +SC+ CK FF+R+I+ +
Sbjct: 100 LYDDCSSTIVEDPQTKCEYMLNSMPKRLCLVCGDIASGYHYGVASCEACKAFFKRTIQGN 159
Query: 81 HVYSCRFSRQCVVDKDKRNQCRYCRLRKCFRAGMKKEAVQNERDRISTRR--STFDGSNI 138
YSC + +C + K +R C+ CR KC + GM KE V+ +R R ++ D N
Sbjct: 160 IEYSCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRVRGGRQKYKRRIDAENS 219
Query: 139 PSINTLAQAEVRS------RQISVSSPGS-----STDINVKKIASIGDVCESMKQQLLVL 187
P +N + + V+ P + I ++ +C+ ++L+V+
Sbjct: 220 PYLNPQLVQPAKKPYNKIVSHLLVAEPEKIYAMPDPTVPDSDIKALTTLCDLADRELVVI 279
Query: 188 VEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMMYKDILLLGNNYVIHRNSCEV 247
+ WAK+IP F L L DQ++LL++ E L+LG RS+ ++D L+ ++Y++ + ++
Sbjct: 280 IGWAKHIPGFSTLSLADQMSLLQSAWMEILILGVVYRSLSFEDELVYADDYIMDEDQSKL 339
Query: 248 EISRVANRVLDELVRPFQEIQIDDNEYACLKAIVFFDPDAKGLSDPVKIKNMRFQVQIGL 307
N + +LV+ ++ ++++ E+ LKAI + D+ + D ++ ++ + L
Sbjct: 340 AGLLDLNNAILQLVKKYKSMKLEKEEFVTLKAIALANSDSMHIEDVEAVQKLQDVLHEAL 399
Query: 308 EDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFVKLFGMVKIDNLLQEML 362
+DY + + R G++L+ LP L+ + + ++ +KL G V + L EML
Sbjct: 400 QDYEAGQHMEDPRRAGKMLMTLPLLRQTSTKAVQHFYNIKLEGKVPMHKLFLEML 454
>gi|197209821 estrogen-related receptor gamma isoform 2 [Homo
sapiens]
Length = 435
Score = 173 bits (439), Expect = 2e-43
Identities = 99/355 (27%), Positives = 183/355 (51%), Gaps = 17/355 (4%)
Query: 25 LYNSSDSSAPETSMNTTDNGVNC----LCAICGDRATGKHYGASSCDGCKGFFRRSIRKS 80
LY+ S+ E + +N LC +CGD A+G HYG +SC+ CK FF+R+I+ +
Sbjct: 77 LYDDCSSTIVEDPQTKCEYMLNSMPKRLCLVCGDIASGYHYGVASCEACKAFFKRTIQGN 136
Query: 81 HVYSCRFSRQCVVDKDKRNQCRYCRLRKCFRAGMKKEAVQNERDRISTRR--STFDGSNI 138
YSC + +C + K +R C+ CR KC + GM KE V+ +R R ++ D N
Sbjct: 137 IEYSCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRVRGGRQKYKRRIDAENS 196
Query: 139 PSINTLAQAEVRS------RQISVSSPGS-----STDINVKKIASIGDVCESMKQQLLVL 187
P +N + + V+ P + I ++ +C+ ++L+V+
Sbjct: 197 PYLNPQLVQPAKKPYNKIVSHLLVAEPEKIYAMPDPTVPDSDIKALTTLCDLADRELVVI 256
Query: 188 VEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMMYKDILLLGNNYVIHRNSCEV 247
+ WAK+IP F L L DQ++LL++ E L+LG RS+ ++D L+ ++Y++ + ++
Sbjct: 257 IGWAKHIPGFSTLSLADQMSLLQSAWMEILILGVVYRSLSFEDELVYADDYIMDEDQSKL 316
Query: 248 EISRVANRVLDELVRPFQEIQIDDNEYACLKAIVFFDPDAKGLSDPVKIKNMRFQVQIGL 307
N + +LV+ ++ ++++ E+ LKAI + D+ + D ++ ++ + L
Sbjct: 317 AGLLDLNNAILQLVKKYKSMKLEKEEFVTLKAIALANSDSMHIEDVEAVQKLQDVLHEAL 376
Query: 308 EDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFVKLFGMVKIDNLLQEML 362
+DY + + R G++L+ LP L+ + + ++ +KL G V + L EML
Sbjct: 377 QDYEAGQHMEDPRRAGKMLMTLPLLRQTSTKAVQHFYNIKLEGKVPMHKLFLEML 431
>gi|14916494 retinoic acid receptor, beta isoform 1 [Homo sapiens]
Length = 448
Score = 162 bits (411), Expect = 4e-40
Identities = 104/351 (29%), Positives = 180/351 (51%), Gaps = 27/351 (7%)
Query: 49 CAICGDRATGKHYGASSCDGCKGFFRRSIRKSHVYSCRFSRQCVVDKDKRNQCRYCRLRK 108
C +C D+++G HYG S+C+GCKGFFRRSI+K+ +Y+C + CV++K RN+C+YCRL+K
Sbjct: 81 CFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNMIYTCHRDKNCVINKVTRNRCQYCRLQK 140
Query: 109 CFRAGMKKEAVQNERDR----ISTRRSTFDGSNIPSINTLAQAEVRSRQISVSS------ 158
CF GM KE+V+N+R++ S + T ++ L + ++ Q + S
Sbjct: 141 CFEVGMSKESVRNDRNKKKKETSKQECTESYEMTAELDDLTEKIRKAHQETFPSLCQLGK 200
Query: 159 --PGSSTDINVKKIASIGDVCESMKQQLLV-LVEWAKYIPAFCELPLDDQVALLRAHAGE 215
SS D V+ + D + + ++ +VE+AK +P F L + DQ+ LL+A +
Sbjct: 201 YTTNSSADHRVRLDLGLWDKFSELATKCIIKIVEFAKRLPGFTGLTIADQITLLKAACLD 260
Query: 216 HLLLGATKRSMMYKDILLLGNNYVIHRNSCEVEISRVANRVLDELVRPFQE----IQIDD 271
L+L R +D + + ++R ++ L +LV F +++DD
Sbjct: 261 ILILRICTRYTPEQDTMTFSDGLTLNR----TQMHNAGFGPLTDLVFTFANQLLPLEMDD 316
Query: 272 NEYACLKAIVFFDPDAKGLSDPVKIKNMRFQVQIGLEDYINDRQYDSRGRFGELLLLLPT 331
E L AI D + L +P K+ ++ + L+ YI R+ F ++L+ +
Sbjct: 317 TETGLLSAICLICGDRQDLEEPTKVDKLQEPLLEALKIYIRKRRPSKPHMFPKILMKITD 376
Query: 332 LQSITWQMIEQIQFVKLFGMVKIDNLLQEMLLGGASNDGSHLHHPMHPHLS 382
L+SI+ + E++ +K+ + L+QEML + S H P+ P S
Sbjct: 377 LRSISAKGAERVITLKMEIPGSMPPLIQEML------ENSEGHEPLTPSSS 421
>gi|7706515 photoreceptor-specific nuclear receptor isoform a [Homo
sapiens]
Length = 367
Score = 157 bits (397), Expect = 2e-38
Identities = 93/310 (30%), Positives = 149/310 (48%), Gaps = 48/310 (15%)
Query: 49 CAICGDRATGKHYGASSCDGCKGFFRRSIRKSHVYSCRF-SRQCVVDKDKRNQCRYCRLR 107
C +CGD ++GKHYG +C+GC GFF+RS+R+ +Y C+ + C VDK RNQC+ CRL+
Sbjct: 47 CRVCGDSSSGKHYGIYACNGCSGFFKRSVRRRLIYRCQVGAGMCPVDKAHRNQCQACRLK 106
Query: 108 KCFRAGMKKEAVQNERDRISTRRSTFDG-------------------------------- 135
KC +AGM ++AVQNER ST + D
Sbjct: 107 KCLQAGMNQDAVQNERQPRSTAQVHLDSMESNTESRPESLVAPPAPAGRSPRGPTPMSAA 166
Query: 136 --------SNIPSINTLAQAEVRSRQISVSSPGSSTDINVKKIAS-----IGDVCESMKQ 182
+++ + T A+ E ++ + + +S + + E+ +
Sbjct: 167 RALGHHFMASLITAETCAKLEPEDADENIDVTSNDPEFPSSPYSSSSPCGLDSIHETSAR 226
Query: 183 QLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMMYKDILLLGNNYVIHR 242
L + V+WAK +P F LP DQV LL E LLGA + S+ LL
Sbjct: 227 LLFMAVKWAKNLPVFSSLPFRDQVILLEEAWSELFLLGAIQWSLPLDSCPLLAPPEASAA 286
Query: 243 NSCE--VEISRVANRVLDELVRPFQEIQIDDNEYACLKAIVFFDPDAKGLSDPVKIKNMR 300
+ + ++ + RVL E + F+ + +D E+AC+KA+V F P+ +GL DP ++ ++
Sbjct: 287 GGAQGRLTLASMETRVLQETISRFRALAVDPTEFACMKALVLFKPETRGLKDPEHVEALQ 346
Query: 301 FQVQIGLEDY 310
Q Q+ L +
Sbjct: 347 DQSQVMLSQH 356
>gi|112181200 retinoic acid receptor, gamma isoform 2 [Homo sapiens]
Length = 443
Score = 154 bits (388), Expect = 2e-37
Identities = 105/382 (27%), Positives = 181/382 (47%), Gaps = 21/382 (5%)
Query: 20 ETMQILYNSSDSSAPETSMNTTDNGVNCLCAICGDRATGKHYGASSCDGCKGFFRRSIRK 79
++++ SS+ P + V C +C D+++G HYG SSC+GCKGFFRRSI+K
Sbjct: 50 QSVETQSTSSEEMVPSSPSPPPPPRVYKPCFVCNDKSSGYHYGVSSCEGCKGFFRRSIQK 109
Query: 80 SHVYSCRFSRQCVVDKDKRNQCRYCRLRKCFRAGMKKEAVQNERDR----ISTRRSTFDG 135
+ VY+C + C+++K RN+C+YCRL+KCF GM KEAV+N+R++ + S
Sbjct: 110 NMVYTCHRDKNCIINKVTRNRCQYCRLQKCFEVGMSKEAVRNDRNKKKKEVKEEGSPDSY 169
Query: 136 SNIPSINTLAQAEVRSRQISVSS--------PGSSTDINVKKIASIGDVCESMKQQLLV- 186
P + L ++ Q + S SS D V+ + D + + ++
Sbjct: 170 ELSPQLEELITKVSKAHQETFPSLCQLGKYTTNSSADHRVQLDLGLWDKFSELATKCIIK 229
Query: 187 LVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMMYKDILLLGNNYVIHRNSCE 246
+VE+AK +P F L + DQ+ LL+A + L+L R +D + + ++R
Sbjct: 230 IVEFAKRLPGFTGLSIADQITLLKAACLDILMLRICTRYTPEQDTMTFSDGLTLNR---- 285
Query: 247 VEISRVANRVLDELVRPFQ----EIQIDDNEYACLKAIVFFDPDAKGLSDPVKIKNMRFQ 302
++ L +LV F +++DD E L AI D L +P K+ ++
Sbjct: 286 TQMHNAGFGPLTDLVFAFAGQLLPLEMDDTETGLLSAICLICGDRMDLEEPEKVDKLQEP 345
Query: 303 VQIGLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFVKLFGMVKIDNLLQEML 362
+ L Y R+ F +L+ + L+ I+ + E+ +K+ + L++EML
Sbjct: 346 LLEALRLYARRRRPSQPYMFPRMLMKITDLRGISTKGAERAITLKMEIPGPMPPLIREML 405
Query: 363 LGGASNDGSHLHHPMHPHLSQD 384
+ HP+ S +
Sbjct: 406 ENPEMFEDDSSQPGPHPNASSE 427
>gi|223718064 retinoic acid receptor, alpha isoform 1 [Homo sapiens]
Length = 462
Score = 153 bits (387), Expect = 3e-37
Identities = 105/392 (26%), Positives = 189/392 (48%), Gaps = 33/392 (8%)
Query: 14 YTTLEFETMQILYNSSDSSAPETSMNTTDNGVNCLCAICGDRATGKHYGASSCDGCKGFF 73
Y+T T++ +SS+ P + C +C D+++G HYG S+C+GCKGFF
Sbjct: 53 YSTPSPATIETQSSSSEEIVPSPPSPPPLPRIYKPCFVCQDKSSGYHYGVSACEGCKGFF 112
Query: 74 RRSIRKSHVYSCRFSRQCVVDKDKRNQCRYCRLRKCFRAGMKKEAVQNERDR----ISTR 129
RRSI+K+ VY+C + C+++K RN+C+YCRL+KCF GM KE+V+N+R++ +
Sbjct: 113 RRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQKCFEVGMSKESVRNDRNKKKKEVPKP 172
Query: 130 RSTFDGSNIPSINTLAQAEVRSR--------QISVSSPGSSTDINVKKIASIGDVCESMK 181
+ + P + L + ++ Q+ + +S++ V + D +
Sbjct: 173 ECSESYTLTPEVGELIEKVRKAHQETFPALCQLGKYTTNNSSEQRVSLDIDLWDKFSELS 232
Query: 182 QQLLV-LVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMMYKDILLLGNNYVI 240
+ ++ VE+AK +P F L + DQ+ LL+A + L+L R +D + + +
Sbjct: 233 TKCIIKTVEFAKQLPGFTTLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDGLTL 292
Query: 241 HRNSCEVEISRVANRVLDELVRPFQE----IQIDDNEYACLKAIVFFDPDAKGLSDPVKI 296
+R ++ L +LV F +++DD E L AI D + L P ++
Sbjct: 293 NR----TQMHNAGFGPLTDLVFAFANQLLPLEMDDAETGLLSAICLICGDRQDLEQPDRV 348
Query: 297 KNMRFQVQIGLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFVKLFGMVKIDN 356
++ + L+ Y+ R+ F ++L+ + L+SI+ + E++ +K+ +
Sbjct: 349 DMLQEPLLEALKVYVRKRRPSRPHMFPKMLMKITDLRSISAKGAERVITLKMEIPGSMPP 408
Query: 357 LLQEML------------LGGASNDGSHLHHP 376
L+QEML GG DG L P
Sbjct: 409 LIQEMLENSEGLDTLSGQPGGGGRDGGGLAPP 440
>gi|4506419 retinoic acid receptor, alpha isoform 1 [Homo sapiens]
Length = 462
Score = 153 bits (387), Expect = 3e-37
Identities = 105/392 (26%), Positives = 189/392 (48%), Gaps = 33/392 (8%)
Query: 14 YTTLEFETMQILYNSSDSSAPETSMNTTDNGVNCLCAICGDRATGKHYGASSCDGCKGFF 73
Y+T T++ +SS+ P + C +C D+++G HYG S+C+GCKGFF
Sbjct: 53 YSTPSPATIETQSSSSEEIVPSPPSPPPLPRIYKPCFVCQDKSSGYHYGVSACEGCKGFF 112
Query: 74 RRSIRKSHVYSCRFSRQCVVDKDKRNQCRYCRLRKCFRAGMKKEAVQNERDR----ISTR 129
RRSI+K+ VY+C + C+++K RN+C+YCRL+KCF GM KE+V+N+R++ +
Sbjct: 113 RRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQKCFEVGMSKESVRNDRNKKKKEVPKP 172
Query: 130 RSTFDGSNIPSINTLAQAEVRSR--------QISVSSPGSSTDINVKKIASIGDVCESMK 181
+ + P + L + ++ Q+ + +S++ V + D +
Sbjct: 173 ECSESYTLTPEVGELIEKVRKAHQETFPALCQLGKYTTNNSSEQRVSLDIDLWDKFSELS 232
Query: 182 QQLLV-LVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMMYKDILLLGNNYVI 240
+ ++ VE+AK +P F L + DQ+ LL+A + L+L R +D + + +
Sbjct: 233 TKCIIKTVEFAKQLPGFTTLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDGLTL 292
Query: 241 HRNSCEVEISRVANRVLDELVRPFQE----IQIDDNEYACLKAIVFFDPDAKGLSDPVKI 296
+R ++ L +LV F +++DD E L AI D + L P ++
Sbjct: 293 NR----TQMHNAGFGPLTDLVFAFANQLLPLEMDDAETGLLSAICLICGDRQDLEQPDRV 348
Query: 297 KNMRFQVQIGLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFVKLFGMVKIDN 356
++ + L+ Y+ R+ F ++L+ + L+SI+ + E++ +K+ +
Sbjct: 349 DMLQEPLLEALKVYVRKRRPSRPHMFPKMLMKITDLRSISAKGAERVITLKMEIPGSMPP 408
Query: 357 LLQEML------------LGGASNDGSHLHHP 376
L+QEML GG DG L P
Sbjct: 409 LIQEMLENSEGLDTLSGQPGGGGRDGGGLAPP 440
>gi|4506423 retinoic acid receptor, gamma isoform 1 [Homo sapiens]
Length = 454
Score = 153 bits (387), Expect = 3e-37
Identities = 105/374 (28%), Positives = 177/374 (47%), Gaps = 21/374 (5%)
Query: 28 SSDSSAPETSMNTTDNGVNCLCAICGDRATGKHYGASSCDGCKGFFRRSIRKSHVYSCRF 87
SS+ P + V C +C D+++G HYG SSC+GCKGFFRRSI+K+ VY+C
Sbjct: 69 SSEEMVPSSPSPPPPPRVYKPCFVCNDKSSGYHYGVSSCEGCKGFFRRSIQKNMVYTCHR 128
Query: 88 SRQCVVDKDKRNQCRYCRLRKCFRAGMKKEAVQNERDR----ISTRRSTFDGSNIPSINT 143
+ C+++K RN+C+YCRL+KCF GM KEAV+N+R++ + S P +
Sbjct: 129 DKNCIINKVTRNRCQYCRLQKCFEVGMSKEAVRNDRNKKKKEVKEEGSPDSYELSPQLEE 188
Query: 144 LAQAEVRSRQISVSS--------PGSSTDINVKKIASIGDVCESMKQQLLV-LVEWAKYI 194
L ++ Q + S SS D V+ + D + + ++ +VE+AK +
Sbjct: 189 LITKVSKAHQETFPSLCQLGKYTTNSSADHRVQLDLGLWDKFSELATKCIIKIVEFAKRL 248
Query: 195 PAFCELPLDDQVALLRAHAGEHLLLGATKRSMMYKDILLLGNNYVIHRNSCEVEISRVAN 254
P F L + DQ+ LL+A + L+L R +D + + ++R ++
Sbjct: 249 PGFTGLSIADQITLLKAACLDILMLRICTRYTPEQDTMTFSDGLTLNR----TQMHNAGF 304
Query: 255 RVLDELVRPFQ----EIQIDDNEYACLKAIVFFDPDAKGLSDPVKIKNMRFQVQIGLEDY 310
L +LV F +++DD E L AI D L +P K+ ++ + L Y
Sbjct: 305 GPLTDLVFAFAGQLLPLEMDDTETGLLSAICLICGDRMDLEEPEKVDKLQEPLLEALRLY 364
Query: 311 INDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFVKLFGMVKIDNLLQEMLLGGASNDG 370
R+ F +L+ + L+ I+ + E+ +K+ + L++EML +
Sbjct: 365 ARRRRPSQPYMFPRMLMKITDLRGISTKGAERAITLKMEIPGPMPPLIREMLENPEMFED 424
Query: 371 SHLHHPMHPHLSQD 384
HP+ S +
Sbjct: 425 DSSQPGPHPNASSE 438
>gi|67459914 retinoic acid receptor, alpha isoform 2 [Homo sapiens]
Length = 457
Score = 152 bits (383), Expect = 8e-37
Identities = 99/357 (27%), Positives = 177/357 (49%), Gaps = 33/357 (9%)
Query: 49 CAICGDRATGKHYGASSCDGCKGFFRRSIRKSHVYSCRFSRQCVVDKDKRNQCRYCRLRK 108
C +C D+++G HYG S+C+GCKGFFRRSI+K+ VY+C + C+++K RN+C+YCRL+K
Sbjct: 83 CFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQK 142
Query: 109 CFRAGMKKEAVQNERDR----ISTRRSTFDGSNIPSINTLAQAEVRSR--------QISV 156
CF GM KE+V+N+R++ + + + P + L + ++ Q+
Sbjct: 143 CFEVGMSKESVRNDRNKKKKEVPKPECSESYTLTPEVGELIEKVRKAHQETFPALCQLGK 202
Query: 157 SSPGSSTDINVKKIASIGDVCESMKQQLLV-LVEWAKYIPAFCELPLDDQVALLRAHAGE 215
+ +S++ V + D + + ++ VE+AK +P F L + DQ+ LL+A +
Sbjct: 203 YTTNNSSEQRVSLDIDLWDKFSELSTKCIIKTVEFAKQLPGFTTLTIADQITLLKAACLD 262
Query: 216 HLLLGATKRSMMYKDILLLGNNYVIHRNSCEVEISRVANRVLDELVRPFQE----IQIDD 271
L+L R +D + + ++R ++ L +LV F +++DD
Sbjct: 263 ILILRICTRYTPEQDTMTFSDGLTLNR----TQMHNAGFGPLTDLVFAFANQLLPLEMDD 318
Query: 272 NEYACLKAIVFFDPDAKGLSDPVKIKNMRFQVQIGLEDYINDRQYDSRGRFGELLLLLPT 331
E L AI D + L P ++ ++ + L+ Y+ R+ F ++L+ +
Sbjct: 319 AETGLLSAICLICGDRQDLEQPDRVDMLQEPLLEALKVYVRKRRPSRPHMFPKMLMKITD 378
Query: 332 LQSITWQMIEQIQFVKLFGMVKIDNLLQEML------------LGGASNDGSHLHHP 376
L+SI+ + E++ +K+ + L+QEML GG DG L P
Sbjct: 379 LRSISAKGAERVITLKMEIPGSMPPLIQEMLENSEGLDTLSGQPGGGGRDGGGLAPP 435
>gi|5453822 nuclear receptor subfamily 4, group A, member 2 [Homo
sapiens]
Length = 598
Score = 148 bits (373), Expect = 1e-35
Identities = 97/335 (28%), Positives = 171/335 (51%), Gaps = 22/335 (6%)
Query: 48 LCAICGDRATGKHYGASSCDGCKGFFRRSIRKSHVYSCRFSRQCVVDKDKRNQCRYCRLR 107
LCA+CGD A +HYG +C+GCKGFF+R+++K+ Y C ++ C VDK +RN+C+YCR +
Sbjct: 262 LCAVCGDNAACQHYGVRTCEGCKGFFKRTVQKNAKYVCLANKNCPVDKRRRNRCQYCRFQ 321
Query: 108 KCFRAGMKKEAVQNE-----RDRISTRRSTFDGSNIPS-----INTLAQAEVRSRQISVS 157
KC GM KE V+ + R R+ ++ + + PS I+ L +A V S S
Sbjct: 322 KCLAVGMVKEVVRTDSLKGRRGRLPSKPKSPQEPSPPSPPVSLISALVRAHVDSNPAMTS 381
Query: 158 SPGSSTDINVKKIASIGDVCESMKQ-------QLLVLVEWAKYIPAFCELPLDDQVALLR 210
S N S GD + ++Q + ++ WA+ IP F +LP DQ L
Sbjct: 382 LDYSRFQANPDYQMS-GDDTQHIQQFYDLLTGSMEIIRGWAEKIPGFADLPKADQDLLFE 440
Query: 211 AHAGEHLLLGATKRSMMYKDILLLGNNYVIHRNSCEVEISRVANRVLDELVRPFQEIQID 270
+ E +L RS + L+ N V+HR C + ++ E Q + ID
Sbjct: 441 SAFLELFVLRLAYRSNPVEGKLIFCNGVVLHRLQCVRGFGEWIDSIV-EFSSNLQNMNID 499
Query: 271 DNEYACLKAIVFFDPDAKGLSDPVKIKNMRFQVQIGLEDYI--NDRQYDSRGRFGELLLL 328
+ ++C+ A+ + GL +P +++ ++ ++ L+D++ N+ + +LL
Sbjct: 500 ISAFSCIAALAMV-TERHGLKEPKRVEELQNKIVNCLKDHVTFNNGGLNRPNYLSKLLGK 558
Query: 329 LPTLQSITWQMIEQIQFVKLFGMVKIDNLLQEMLL 363
LP L+++ Q +++I ++KL +V ++ ++ L
Sbjct: 559 LPELRTLCTQGLQRIFYLKLEDLVPPPAIIDKLFL 593
>gi|27894344 nuclear receptor subfamily 4, group A, member 1 [Homo
sapiens]
Length = 598
Score = 136 bits (343), Expect = 3e-32
Identities = 96/339 (28%), Positives = 168/339 (49%), Gaps = 34/339 (10%)
Query: 49 CAICGDRATGKHYGASSCDGCKGFFRRSIRKSHVYSCRFSRQCVVDKDKRNQCRYCRLRK 108
CA+CGD A+ +HYG +C+GCKGFF+R+++K+ Y C ++ C VDK +RN+C++CR +K
Sbjct: 267 CAVCGDNASCQHYGVRTCEGCKGFFKRTVQKNAKYICLANKDCPVDKRRRNRCQFCRFQK 326
Query: 109 CFRAGMKKEAVQNE-----RDRISTR-RSTFDGSNIPSINTLAQAEVRSRQISVSSPGSS 162
C GM KE V+ + R R+ ++ + D S + +L +A + S S+
Sbjct: 327 CLAVGMVKEVVRTDSLKGRRGRLPSKPKQPPDASPANLLTSLVRAH-------LDSGPST 379
Query: 163 TDINVKKIASI----------GDV---CESMKQQLLVLVEWAKYIPAFCELPLDDQVALL 209
++ K + GDV + + L V+ +WA+ IP F EL DQ LL
Sbjct: 380 AKLDYSKFQELVLPHFGKEDAGDVQQFYDLLSGSLEVIRKWAEKIPGFAELSPADQDLLL 439
Query: 210 RAHAGEHLLLGATKRSMMYKDILLLGNNYVIHRNSCEVEISRVANRVLDELVRPFQEIQI 269
+ E +L RS + L+ + V+HR C + +L R + +
Sbjct: 440 ESAFLELFILRLAYRSKPGEGKLIFCSGLVLHRLQCARGFGDWIDSIL-AFSRSLHSLLV 498
Query: 270 DDNEYACLKAIVFFDPDAKGLSDPVKIKNMRFQVQIGLEDYIN--DRQYDSRGRFGELLL 327
D +ACL A+V D GL +P +++ ++ ++ L++++ + LL
Sbjct: 499 DVPAFACLSALVLI-TDRHGLQEPRRVEELQNRIASCLKEHVAAVAGEPQPASCLSRLLG 557
Query: 328 LLPTLQSITWQMIEQIQFVKLFGMVK----IDNLLQEML 362
LP L+++ Q +++I ++KL +V ID + + L
Sbjct: 558 KLPELRTLCTQGLQRIFYLKLEDLVPPPPIIDKIFMDTL 596
>gi|21361342 nuclear receptor subfamily 4, group A, member 1 [Homo
sapiens]
Length = 598
Score = 136 bits (343), Expect = 3e-32
Identities = 96/339 (28%), Positives = 168/339 (49%), Gaps = 34/339 (10%)
Query: 49 CAICGDRATGKHYGASSCDGCKGFFRRSIRKSHVYSCRFSRQCVVDKDKRNQCRYCRLRK 108
CA+CGD A+ +HYG +C+GCKGFF+R+++K+ Y C ++ C VDK +RN+C++CR +K
Sbjct: 267 CAVCGDNASCQHYGVRTCEGCKGFFKRTVQKNAKYICLANKDCPVDKRRRNRCQFCRFQK 326
Query: 109 CFRAGMKKEAVQNE-----RDRISTR-RSTFDGSNIPSINTLAQAEVRSRQISVSSPGSS 162
C GM KE V+ + R R+ ++ + D S + +L +A + S S+
Sbjct: 327 CLAVGMVKEVVRTDSLKGRRGRLPSKPKQPPDASPANLLTSLVRAH-------LDSGPST 379
Query: 163 TDINVKKIASI----------GDV---CESMKQQLLVLVEWAKYIPAFCELPLDDQVALL 209
++ K + GDV + + L V+ +WA+ IP F EL DQ LL
Sbjct: 380 AKLDYSKFQELVLPHFGKEDAGDVQQFYDLLSGSLEVIRKWAEKIPGFAELSPADQDLLL 439
Query: 210 RAHAGEHLLLGATKRSMMYKDILLLGNNYVIHRNSCEVEISRVANRVLDELVRPFQEIQI 269
+ E +L RS + L+ + V+HR C + +L R + +
Sbjct: 440 ESAFLELFILRLAYRSKPGEGKLIFCSGLVLHRLQCARGFGDWIDSIL-AFSRSLHSLLV 498
Query: 270 DDNEYACLKAIVFFDPDAKGLSDPVKIKNMRFQVQIGLEDYIN--DRQYDSRGRFGELLL 327
D +ACL A+V D GL +P +++ ++ ++ L++++ + LL
Sbjct: 499 DVPAFACLSALVLI-TDRHGLQEPRRVEELQNRIASCLKEHVAAVAGEPQPASCLSRLLG 557
Query: 328 LLPTLQSITWQMIEQIQFVKLFGMVK----IDNLLQEML 362
LP L+++ Q +++I ++KL +V ID + + L
Sbjct: 558 KLPELRTLCTQGLQRIFYLKLEDLVPPPPIIDKIFMDTL 596
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.134 0.396
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,707,103
Number of Sequences: 37866
Number of extensions: 741530
Number of successful extensions: 2813
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 118
Number of HSP's successfully gapped in prelim test: 17
Number of HSP's that attempted gapping in prelim test: 2489
Number of HSP's gapped (non-prelim): 188
length of query: 445
length of database: 18,247,518
effective HSP length: 105
effective length of query: 340
effective length of database: 14,271,588
effective search space: 4852339920
effective search space used: 4852339920
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.