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Search of human proteins with 23503243
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|23503243 Ras association (RalGDS/AF-6) domain family
(N-terminal) member 8 [Homo sapiens]
(392 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|23503243 Ras association (RalGDS/AF-6) domain family (N-termi... 766 0.0
gi|221136876 Ras association (RalGDS/AF-6) domain family (N-term... 182 5e-46
gi|221136872 Ras association (RalGDS/AF-6) domain family (N-term... 182 5e-46
gi|4502483 Ras association (RalGDS/AF-6) domain family (N-termin... 182 5e-46
gi|114155158 Ras association (RalGDS/AF-6) domain family (N-term... 81 1e-15
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 68 2e-11
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 68 2e-11
gi|21735548 centrosomal protein 2 [Homo sapiens] 65 8e-11
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 65 8e-11
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 64 2e-10
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 63 5e-10
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 63 5e-10
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 62 9e-10
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 62 1e-09
gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens] 60 3e-09
gi|71061468 centromere protein E [Homo sapiens] 60 3e-09
gi|229577185 epidermal growth factor receptor pathway substrate ... 59 6e-09
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 59 6e-09
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 59 8e-09
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 59 8e-09
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 59 8e-09
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 59 8e-09
gi|96975038 coiled-coil domain containing 100 [Homo sapiens] 59 1e-08
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 58 1e-08
gi|221316624 dystonin isoform 4 [Homo sapiens] 58 1e-08
gi|221316622 dystonin isoform 3 [Homo sapiens] 58 1e-08
gi|221316618 dystonin isoform 2 [Homo sapiens] 58 1e-08
gi|34577047 dystonin isoform 1 [Homo sapiens] 58 1e-08
gi|34577049 dystonin isoform 1eA precursor [Homo sapiens] 58 1e-08
gi|145312241 differentially expressed in FDCP 6 homolog [Homo sa... 58 2e-08
>gi|23503243 Ras association (RalGDS/AF-6) domain family
(N-terminal) member 8 [Homo sapiens]
Length = 392
Score = 766 bits (1979), Expect = 0.0
Identities = 392/392 (100%), Positives = 392/392 (100%)
Query: 1 MELKVWVDGVQRIVCGVTEVTTCQEVVIALAQAIGRTGRYTLIEKWRDTERHLAPHENPI 60
MELKVWVDGVQRIVCGVTEVTTCQEVVIALAQAIGRTGRYTLIEKWRDTERHLAPHENPI
Sbjct: 1 MELKVWVDGVQRIVCGVTEVTTCQEVVIALAQAIGRTGRYTLIEKWRDTERHLAPHENPI 60
Query: 61 ISLNKWGQYASDVQLILRRTGPSLSERPTSDSVARIPERTLYRQSLPPLAKLRPQIDKSI 120
ISLNKWGQYASDVQLILRRTGPSLSERPTSDSVARIPERTLYRQSLPPLAKLRPQIDKSI
Sbjct: 61 ISLNKWGQYASDVQLILRRTGPSLSERPTSDSVARIPERTLYRQSLPPLAKLRPQIDKSI 120
Query: 121 KRREPKRKSLTFTGGAKGLMDIFGKGKETEFKQKVLNNCKTTADELKKLIRLQTEKLQSI 180
KRREPKRKSLTFTGGAKGLMDIFGKGKETEFKQKVLNNCKTTADELKKLIRLQTEKLQSI
Sbjct: 121 KRREPKRKSLTFTGGAKGLMDIFGKGKETEFKQKVLNNCKTTADELKKLIRLQTEKLQSI 180
Query: 181 EKQLESNEIEIRFWEQKYNSNLEEEIVRLEQKIKRNDVEIEEEEFWENELQIEQENEKQL 240
EKQLESNEIEIRFWEQKYNSNLEEEIVRLEQKIKRNDVEIEEEEFWENELQIEQENEKQL
Sbjct: 181 EKQLESNEIEIRFWEQKYNSNLEEEIVRLEQKIKRNDVEIEEEEFWENELQIEQENEKQL 240
Query: 241 KDQLQEIRQKITECENKLKDYLAQIRTMESGLEAEKLQREVQEAQVNEEEVKGKIGKVKG 300
KDQLQEIRQKITECENKLKDYLAQIRTMESGLEAEKLQREVQEAQVNEEEVKGKIGKVKG
Sbjct: 241 KDQLQEIRQKITECENKLKDYLAQIRTMESGLEAEKLQREVQEAQVNEEEVKGKIGKVKG 300
Query: 301 EIDIQGQQSLRLENGIKAVERSLGQATKRLQDKEQELEQLTKELRQVNLQQFIQQTGTKV 360
EIDIQGQQSLRLENGIKAVERSLGQATKRLQDKEQELEQLTKELRQVNLQQFIQQTGTKV
Sbjct: 301 EIDIQGQQSLRLENGIKAVERSLGQATKRLQDKEQELEQLTKELRQVNLQQFIQQTGTKV 360
Query: 361 TVLPAEPIEIEASHADIERGIIILSDKQECKD 392
TVLPAEPIEIEASHADIERGIIILSDKQECKD
Sbjct: 361 TVLPAEPIEIEASHADIERGIIILSDKQECKD 392
>gi|221136876 Ras association (RalGDS/AF-6) domain family
(N-terminal) member 7 isoform 3 [Homo sapiens]
Length = 320
Score = 182 bits (462), Expect = 5e-46
Identities = 138/372 (37%), Positives = 190/372 (51%), Gaps = 77/372 (20%)
Query: 1 MELKVWVDGVQRIVCGVTEVTTCQEVVIALAQAIGRTGRYTLIEKWRDTERHLAPHENPI 60
MELKVWVDG+QR+VCGV+E TTCQEVVIALAQAIG+TGR+ L+++ R+ ER L P E P+
Sbjct: 8 MELKVWVDGIQRVVCGVSEQTTCQEVVIALAQAIGQTGRFVLVQRLREKERQLLPQECPV 67
Query: 61 ISLNKWGQYASDVQLILRRTGPSLSERPTSDSVARIPERTLYRQSLP--PLAKLRPQIDK 118
+ GQ+ASDVQ +LRRTGPSL+ RP+SDS PER L R SLP P A L + K
Sbjct: 68 GAQATCGQFASDVQFVLRRTGPSLAGRPSSDSCPP-PERCLIRASLPVKPRAALGCEPRK 126
Query: 119 SIKRREPKRKSLTFTGGAKGLMDIFGKGKETEFKQKVLNNCKTTADELKKLIRLQTEKLQ 178
++ EP SL+ G A + G C T L+
Sbjct: 127 TL-TPEP-APSLSRPGPAAPVTPTPG--------------CCT--------------DLR 156
Query: 179 SIEKQLESNEIEI---RFWEQKYNSNLEEEIVRLEQKIKRNDVEIEEEEFWENELQIEQE 235
+E +++ N E+ FWEQ EL+ EQ
Sbjct: 157 GLELRVQRNAEELGHEAFWEQ--------------------------------ELRREQA 184
Query: 236 NEKQLKDQLQEIRQKITECENKLKDYLAQIRTMESGLEAEKLQREVQEAQVNEEEVKGKI 295
E++ + +LQ + E +L+ AQ R +E+ L+ EA +
Sbjct: 185 REREGQARLQALSAATAEHAARLQALDAQARALEAELQL------AAEAPGPPSPMASAT 238
Query: 296 GKVKGEIDIQGQQSLRLENGIKAVERSLGQATKRLQDKEQELEQLTKELRQVNLQQFIQQ 355
++ ++ +Q +QS ++ + V R+L A + LQ + QELE+L +ELRQ NLQQFIQQ
Sbjct: 239 ERLHQDLAVQERQSAEVQGSLALVSRALEAAERALQAQAQELEELNRELRQCNLQQFIQQ 298
Query: 356 TGTKVTVLPAEP 367
TG LP P
Sbjct: 299 TG---AALPPPP 307
>gi|221136872 Ras association (RalGDS/AF-6) domain family
(N-terminal) member 7 isoform 2 [Homo sapiens]
Length = 337
Score = 182 bits (462), Expect = 5e-46
Identities = 138/372 (37%), Positives = 190/372 (51%), Gaps = 77/372 (20%)
Query: 1 MELKVWVDGVQRIVCGVTEVTTCQEVVIALAQAIGRTGRYTLIEKWRDTERHLAPHENPI 60
MELKVWVDG+QR+VCGV+E TTCQEVVIALAQAIG+TGR+ L+++ R+ ER L P E P+
Sbjct: 8 MELKVWVDGIQRVVCGVSEQTTCQEVVIALAQAIGQTGRFVLVQRLREKERQLLPQECPV 67
Query: 61 ISLNKWGQYASDVQLILRRTGPSLSERPTSDSVARIPERTLYRQSLP--PLAKLRPQIDK 118
+ GQ+ASDVQ +LRRTGPSL+ RP+SDS PER L R SLP P A L + K
Sbjct: 68 GAQATCGQFASDVQFVLRRTGPSLAGRPSSDSCPP-PERCLIRASLPVKPRAALGCEPRK 126
Query: 119 SIKRREPKRKSLTFTGGAKGLMDIFGKGKETEFKQKVLNNCKTTADELKKLIRLQTEKLQ 178
++ EP SL+ G A + G C T L+
Sbjct: 127 TL-TPEP-APSLSRPGPAAPVTPTPG--------------CCT--------------DLR 156
Query: 179 SIEKQLESNEIEI---RFWEQKYNSNLEEEIVRLEQKIKRNDVEIEEEEFWENELQIEQE 235
+E +++ N E+ FWEQ EL+ EQ
Sbjct: 157 GLELRVQRNAEELGHEAFWEQ--------------------------------ELRREQA 184
Query: 236 NEKQLKDQLQEIRQKITECENKLKDYLAQIRTMESGLEAEKLQREVQEAQVNEEEVKGKI 295
E++ + +LQ + E +L+ AQ R +E+ L+ EA +
Sbjct: 185 REREGQARLQALSAATAEHAARLQALDAQARALEAELQL------AAEAPGPPSPMASAT 238
Query: 296 GKVKGEIDIQGQQSLRLENGIKAVERSLGQATKRLQDKEQELEQLTKELRQVNLQQFIQQ 355
++ ++ +Q +QS ++ + V R+L A + LQ + QELE+L +ELRQ NLQQFIQQ
Sbjct: 239 ERLHQDLAVQERQSAEVQGSLALVSRALEAAERALQAQAQELEELNRELRQCNLQQFIQQ 298
Query: 356 TGTKVTVLPAEP 367
TG LP P
Sbjct: 299 TG---AALPPPP 307
>gi|4502483 Ras association (RalGDS/AF-6) domain family (N-terminal)
member 7 isoform 1 [Homo sapiens]
Length = 373
Score = 182 bits (462), Expect = 5e-46
Identities = 138/372 (37%), Positives = 190/372 (51%), Gaps = 77/372 (20%)
Query: 1 MELKVWVDGVQRIVCGVTEVTTCQEVVIALAQAIGRTGRYTLIEKWRDTERHLAPHENPI 60
MELKVWVDG+QR+VCGV+E TTCQEVVIALAQAIG+TGR+ L+++ R+ ER L P E P+
Sbjct: 8 MELKVWVDGIQRVVCGVSEQTTCQEVVIALAQAIGQTGRFVLVQRLREKERQLLPQECPV 67
Query: 61 ISLNKWGQYASDVQLILRRTGPSLSERPTSDSVARIPERTLYRQSLP--PLAKLRPQIDK 118
+ GQ+ASDVQ +LRRTGPSL+ RP+SDS PER L R SLP P A L + K
Sbjct: 68 GAQATCGQFASDVQFVLRRTGPSLAGRPSSDSCPP-PERCLIRASLPVKPRAALGCEPRK 126
Query: 119 SIKRREPKRKSLTFTGGAKGLMDIFGKGKETEFKQKVLNNCKTTADELKKLIRLQTEKLQ 178
++ EP SL+ G A + G C T L+
Sbjct: 127 TL-TPEP-APSLSRPGPAAPVTPTPG--------------CCT--------------DLR 156
Query: 179 SIEKQLESNEIEI---RFWEQKYNSNLEEEIVRLEQKIKRNDVEIEEEEFWENELQIEQE 235
+E +++ N E+ FWEQ EL+ EQ
Sbjct: 157 GLELRVQRNAEELGHEAFWEQ--------------------------------ELRREQA 184
Query: 236 NEKQLKDQLQEIRQKITECENKLKDYLAQIRTMESGLEAEKLQREVQEAQVNEEEVKGKI 295
E++ + +LQ + E +L+ AQ R +E+ L+ EA +
Sbjct: 185 REREGQARLQALSAATAEHAARLQALDAQARALEAELQL------AAEAPGPPSPMASAT 238
Query: 296 GKVKGEIDIQGQQSLRLENGIKAVERSLGQATKRLQDKEQELEQLTKELRQVNLQQFIQQ 355
++ ++ +Q +QS ++ + V R+L A + LQ + QELE+L +ELRQ NLQQFIQQ
Sbjct: 239 ERLHQDLAVQERQSAEVQGSLALVSRALEAAERALQAQAQELEELNRELRQCNLQQFIQQ 298
Query: 356 TGTKVTVLPAEP 367
TG LP P
Sbjct: 299 TG---AALPPPP 307
>gi|114155158 Ras association (RalGDS/AF-6) domain family
(N-terminal) member 9 [Homo sapiens]
Length = 435
Score = 81.3 bits (199), Expect = 1e-15
Identities = 88/403 (21%), Positives = 167/403 (41%), Gaps = 63/403 (15%)
Query: 2 ELKVWVDGVQRIVCGVTEVTTCQEVVIALAQA-----------IGRTGRYTLIEKWRDTE 50
E+ VWV +++VCG+T+ TT +V+ AL + +G+ Y +IEKWR +E
Sbjct: 28 EIVVWVCQEEKLVCGLTKRTTSADVIQALLEEHEATFGEKRFLLGKPSDYCIIEKWRGSE 87
Query: 51 RHLAPHENPIISLNKWGQYASDVQLILRRTGPSLSERPTSDSVARIPERTLYRQSLPP-- 108
R L P + WG ++Q +L + L + A++ + T L P
Sbjct: 88 RVLPPLTRILKLWKAWGDEQPNMQFVLVKADAFLPVPLWRTAEAKLVQNTEKLWELSPAN 147
Query: 109 -LAKLRPQIDKSIKRREPKRKSLTFTGGAKGLMDIFGKGKETEFKQKVLNNCKTTADELK 167
+ L P K I R+ TF K + KQ +++ + + L
Sbjct: 148 YMKTLPPDKQKRIVRK-------TFR-------------KLAKIKQDTVSHDRDNMETLV 187
Query: 168 KLIRLQTEKLQSIEKQLESNEIEIRFWEQKYNSNLEEEIVRLEQKIKRNDVEIEEEEFW- 226
LI Q + K+++ ++EI E K++ + E ND E ++ +
Sbjct: 188 HLIISQDHTIHQQVKRMKELDLEIEKCEAKFHLDRVE-----------NDGENYVQDAYL 236
Query: 227 -------ENELQIEQENEKQLKDQLQEIRQKITECENKLKDYLAQIRTMESGLEAEKLQ- 278
E L ++ E + L+D + I + E +LK Y I + + +E E
Sbjct: 237 MPSFSEVEQNLDLQYEENQTLEDLSES--DGIEQLEERLKYYRILIDKLSAEIEKEVKSV 294
Query: 279 ----REVQEAQVNEEEVKGKIGKVKGEIDIQGQQSLRLENGIKAVERSLGQATKRLQDKE 334
E E + E + VK +++ + L++ + + +++ + + LQ K
Sbjct: 295 CIDINEDAEGEAASELESSNLESVKCDLEKSMKAGLKIHSHLSGIQKEIKYSDSLLQMKA 354
Query: 335 QELEQLTKELRQVNLQQFIQQTGTKVTVLPAEPIEIEASHADI 377
+E E L KE +++ + G ++ A+ E+ +S+ +I
Sbjct: 355 KEYELLAKEFNSLHIS---NKDGCQLKENRAKESEVPSSNGEI 394
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 67.8 bits (164), Expect = 2e-11
Identities = 58/229 (25%), Positives = 126/229 (55%), Gaps = 28/229 (12%)
Query: 170 IRLQTEKLQSIEKQLESNEIEIRFWEQKYNSNLEEEIVRLEQKIKRNDVEI--EEEEFWE 227
IR Q EK+Q E+++ E +IR E+K +E++ R E+K++ D +I +EEE W
Sbjct: 376 IREQDEKIQEQEEEMWRQEEKIREQEEK----RQEKMWRQEKKMREQDEKIREQEEEMWR 431
Query: 228 NELQIEQENEKQLKDQ---LQEIRQKITECENKLKDYLAQIRTMESGLE--------AEK 276
E +I +E E+ ++DQ L+E+ +K+ E E K+++ +I+ E ++ EK
Sbjct: 432 QEEKI-RELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEK 490
Query: 277 LQREVQEAQVNEEEV---KGKIGKVKGEIDIQGQQSLRLENGIKAVERSLGQATKRLQDK 333
L ++ ++ EE++ + K+ + + ++ Q ++ R E ++ E L Q +++Q++
Sbjct: 491 LLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQ 550
Query: 334 EQELEQLTKELRQVNLQQFI-----QQTGTK--VTVLPAEPIEIEASHA 375
E L++L + L ++ + + +++G++ T+ P +E+++ A
Sbjct: 551 EVRLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEA 599
Score = 65.5 bits (158), Expect = 8e-11
Identities = 55/185 (29%), Positives = 100/185 (54%), Gaps = 15/185 (8%)
Query: 170 IRLQTEKLQSIEKQLESNEIEIRFWEQKYNSNLEEEIVRLEQKIKRNDVEIEEEEFWENE 229
IR Q EK++ E+++ E +IR ++K EEE+ R E+KI+ + E +E+ W E
Sbjct: 355 IREQEEKIREQEEKMWRQEEKIREQDEKIQEQ-EEEMWRQEEKIREQE-EKRQEKMWRQE 412
Query: 230 LQIEQENEKQLKDQLQEI---RQKITECENKLKDYLAQIRTMESGLEAEKLQREVQEAQV 286
++ +++EK +++Q +E+ +KI E E ++D ++R +E EK+Q E E ++
Sbjct: 413 KKMREQDEK-IREQEEEMWRQEEKIRELEEMMQDQEEKLREVE-----EKMQEE--EEKM 464
Query: 287 NEEEVKGKIGKVKGEIDIQGQQSLRLENGIKAVERSLGQATKRLQDKEQELEQLTKELRQ 346
E+E KI + + +I Q +++ R E +K E+ Q K + +E+ EQ K Q
Sbjct: 465 QEQE--EKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQ 522
Query: 347 VNLQQ 351
Q
Sbjct: 523 EEKMQ 527
Score = 60.5 bits (145), Expect = 3e-09
Identities = 47/176 (26%), Positives = 93/176 (52%), Gaps = 6/176 (3%)
Query: 173 QTEKLQSIEKQLESNEIEIRFWEQKYNSNLEEEIVRLEQKIKRNDVEIEE--EEFWENEL 230
Q EK++ E ++ E +IR E+K EE++ R E+KI+ D +I+E EE W E
Sbjct: 337 QEEKIREQEDKMWRQEEKIREQEEKIREQ-EEKMWRQEEKIREQDEKIQEQEEEMWRQEE 395
Query: 231 QIEQENEKQLKDQLQEIRQKITECENKLKDYLAQIRTMESGLEAEKLQREVQEAQVNEEE 290
+I ++ EK+ ++++ +K+ E + K+++ ++ E + + + QE ++ E
Sbjct: 396 KIREQEEKR-QEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLR--E 452
Query: 291 VKGKIGKVKGEIDIQGQQSLRLENGIKAVERSLGQATKRLQDKEQELEQLTKELRQ 346
V+ K+ + + ++ Q ++ R E I+ E + K L+ +E+ EQ K RQ
Sbjct: 453 VEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQ 508
Score = 60.5 bits (145), Expect = 3e-09
Identities = 48/207 (23%), Positives = 113/207 (54%), Gaps = 18/207 (8%)
Query: 165 ELKKLIRLQTEKLQSIEKQLESNEIEIRFWEQKYNSNLEEEIVRLEQKIKRNDVEIEEEE 224
EL+++++ Q EKL+ +E++++ E +++ E+K EE+I E+K R + +++EE
Sbjct: 438 ELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQ-EEKIQEQEEKTWRQEKLLKQEE 496
Query: 225 -FWENELQIEQENEK--QLKDQLQEIRQKITECENKLKDYLAQIRTMESGLEAEKLQREV 281
WE E ++ ++ EK + ++++QE +K+ E K+++ ++R + + ++
Sbjct: 497 KIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMRE--QEVRLWQQ-------EEKM 547
Query: 282 QEAQVNEEEVKGKIGKVKGEIDIQGQQSLRLENGIKAVERSLGQATKRLQDKEQELEQLT 341
QE +V +E++ ++GK+ + ++ G E+G + + L+ +E + Q
Sbjct: 548 QEQEVRLQELEERLGKLGQKAELLG--GAGRESGSQRLPTLTPILQVELKSQEAQSLQQQ 605
Query: 342 KELRQVNLQQFI---QQTGTKVTVLPA 365
++ + +LQQ++ QQ + LP+
Sbjct: 606 QDHYRGHLQQYVAAYQQLASGKEALPS 632
Score = 54.7 bits (130), Expect = 1e-07
Identities = 60/310 (19%), Positives = 141/310 (45%), Gaps = 34/310 (10%)
Query: 97 PERTLYRQSL--PPLAKLRPQIDKSIKRREPKRKSLTFTGGAKGLMDIFGKGKETEFKQK 154
PE +L ++L ++ I+K K R+ L + D K K E ++K
Sbjct: 171 PENSLLEETLHFDHAVRMGTYIEKLTKERDAPSLELY----RNTITDEELKEKNAELQEK 226
Query: 155 VLNNCKTTADELKKLIRLQTEKLQSIEKQLESNEIEIRFWEQKYNSNLEEEIVRLEQKIK 214
L ++ E++ ++ KL+ + L ++++ + L+ +L+ +++
Sbjct: 227 -LRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVE--ADRLGKELQSVSAKLQAQVE 283
Query: 215 RNDV-----EIEEEEFWENELQIEQENEKQLKDQL--QEIRQKITECENKLKDYLAQIRT 267
N++ + +EE+ W E +I+++ EK + +L +E +K+ E K+ + +IR
Sbjct: 284 ENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIRE 343
Query: 268 MESGLEAEKLQREVQEAQVNEEEVK-----GKIGKVKGEIDIQGQQSLRLENGIK----- 317
E + ++ + QE ++ E+E K KI + +I Q ++ R E I+
Sbjct: 344 QEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEK 403
Query: 318 ------AVERSLGQATKRLQDKEQELEQLTKELRQVNLQQFIQQTGTKVTVLPAEPIEIE 371
E+ + + ++++++E+E+ + +++R+ L++ +Q K+ + + E E
Sbjct: 404 RQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRE--LEEMMQDQEEKLREVEEKMQEEE 461
Query: 372 ASHADIERGI 381
+ E I
Sbjct: 462 EKMQEQEEKI 471
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 67.8 bits (164), Expect = 2e-11
Identities = 58/229 (25%), Positives = 126/229 (55%), Gaps = 28/229 (12%)
Query: 170 IRLQTEKLQSIEKQLESNEIEIRFWEQKYNSNLEEEIVRLEQKIKRNDVEI--EEEEFWE 227
IR Q EK+Q E+++ E +IR E+K +E++ R E+K++ D +I +EEE W
Sbjct: 376 IREQDEKIQEQEEEMWRQEEKIREQEEK----RQEKMWRQEKKMREQDEKIREQEEEMWR 431
Query: 228 NELQIEQENEKQLKDQ---LQEIRQKITECENKLKDYLAQIRTMESGLE--------AEK 276
E +I +E E+ ++DQ L+E+ +K+ E E K+++ +I+ E ++ EK
Sbjct: 432 QEEKI-RELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEK 490
Query: 277 LQREVQEAQVNEEEV---KGKIGKVKGEIDIQGQQSLRLENGIKAVERSLGQATKRLQDK 333
L ++ ++ EE++ + K+ + + ++ Q ++ R E ++ E L Q +++Q++
Sbjct: 491 LLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQ 550
Query: 334 EQELEQLTKELRQVNLQQFI-----QQTGTK--VTVLPAEPIEIEASHA 375
E L++L + L ++ + + +++G++ T+ P +E+++ A
Sbjct: 551 EVRLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEA 599
Score = 65.5 bits (158), Expect = 8e-11
Identities = 55/185 (29%), Positives = 100/185 (54%), Gaps = 15/185 (8%)
Query: 170 IRLQTEKLQSIEKQLESNEIEIRFWEQKYNSNLEEEIVRLEQKIKRNDVEIEEEEFWENE 229
IR Q EK++ E+++ E +IR ++K EEE+ R E+KI+ + E +E+ W E
Sbjct: 355 IREQEEKIREQEEKMWRQEEKIREQDEKIQEQ-EEEMWRQEEKIREQE-EKRQEKMWRQE 412
Query: 230 LQIEQENEKQLKDQLQEI---RQKITECENKLKDYLAQIRTMESGLEAEKLQREVQEAQV 286
++ +++EK +++Q +E+ +KI E E ++D ++R +E EK+Q E E ++
Sbjct: 413 KKMREQDEK-IREQEEEMWRQEEKIRELEEMMQDQEEKLREVE-----EKMQEE--EEKM 464
Query: 287 NEEEVKGKIGKVKGEIDIQGQQSLRLENGIKAVERSLGQATKRLQDKEQELEQLTKELRQ 346
E+E KI + + +I Q +++ R E +K E+ Q K + +E+ EQ K Q
Sbjct: 465 QEQE--EKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQ 522
Query: 347 VNLQQ 351
Q
Sbjct: 523 EEKMQ 527
Score = 60.5 bits (145), Expect = 3e-09
Identities = 47/176 (26%), Positives = 93/176 (52%), Gaps = 6/176 (3%)
Query: 173 QTEKLQSIEKQLESNEIEIRFWEQKYNSNLEEEIVRLEQKIKRNDVEIEE--EEFWENEL 230
Q EK++ E ++ E +IR E+K EE++ R E+KI+ D +I+E EE W E
Sbjct: 337 QEEKIREQEDKMWRQEEKIREQEEKIREQ-EEKMWRQEEKIREQDEKIQEQEEEMWRQEE 395
Query: 231 QIEQENEKQLKDQLQEIRQKITECENKLKDYLAQIRTMESGLEAEKLQREVQEAQVNEEE 290
+I ++ EK+ ++++ +K+ E + K+++ ++ E + + + QE ++ E
Sbjct: 396 KIREQEEKR-QEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLR--E 452
Query: 291 VKGKIGKVKGEIDIQGQQSLRLENGIKAVERSLGQATKRLQDKEQELEQLTKELRQ 346
V+ K+ + + ++ Q ++ R E I+ E + K L+ +E+ EQ K RQ
Sbjct: 453 VEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQ 508
Score = 60.5 bits (145), Expect = 3e-09
Identities = 48/207 (23%), Positives = 113/207 (54%), Gaps = 18/207 (8%)
Query: 165 ELKKLIRLQTEKLQSIEKQLESNEIEIRFWEQKYNSNLEEEIVRLEQKIKRNDVEIEEEE 224
EL+++++ Q EKL+ +E++++ E +++ E+K EE+I E+K R + +++EE
Sbjct: 438 ELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQ-EEKIQEQEEKTWRQEKLLKQEE 496
Query: 225 -FWENELQIEQENEK--QLKDQLQEIRQKITECENKLKDYLAQIRTMESGLEAEKLQREV 281
WE E ++ ++ EK + ++++QE +K+ E K+++ ++R + + ++
Sbjct: 497 KIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMRE--QEVRLWQQ-------EEKM 547
Query: 282 QEAQVNEEEVKGKIGKVKGEIDIQGQQSLRLENGIKAVERSLGQATKRLQDKEQELEQLT 341
QE +V +E++ ++GK+ + ++ G E+G + + L+ +E + Q
Sbjct: 548 QEQEVRLQELEERLGKLGQKAELLG--GAGRESGSQRLPTLTPILQVELKSQEAQSLQQQ 605
Query: 342 KELRQVNLQQFI---QQTGTKVTVLPA 365
++ + +LQQ++ QQ + LP+
Sbjct: 606 QDHYRGHLQQYVAAYQQLASGKEALPS 632
Score = 55.1 bits (131), Expect = 1e-07
Identities = 60/310 (19%), Positives = 143/310 (46%), Gaps = 34/310 (10%)
Query: 97 PERTLYRQSL--PPLAKLRPQIDKSIKRREPKRKSLTFTGGAKGLMDIFGKGKETEFKQK 154
PE +L ++L ++ I+K K R+ +L+ + D K K E ++K
Sbjct: 171 PENSLLEETLHFDHAVRMGTYIEKLTKERD----ALSLELYRNTITDEELKEKNAELQEK 226
Query: 155 VLNNCKTTADELKKLIRLQTEKLQSIEKQLESNEIEIRFWEQKYNSNLEEEIVRLEQKIK 214
L ++ E++ ++ KL+ + L ++++ + L+ +L+ +++
Sbjct: 227 -LRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVE--ADRLGKELQSVSAKLQAQVE 283
Query: 215 RNDV-----EIEEEEFWENELQIEQENEKQLKDQL--QEIRQKITECENKLKDYLAQIRT 267
N++ + +EE+ W E +I+++ EK + +L +E +K+ E K+ + +IR
Sbjct: 284 ENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIRE 343
Query: 268 MESGLEAEKLQREVQEAQVNEEEVK-----GKIGKVKGEIDIQGQQSLRLENGIK----- 317
E + ++ + QE ++ E+E K KI + +I Q ++ R E I+
Sbjct: 344 QEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEK 403
Query: 318 ------AVERSLGQATKRLQDKEQELEQLTKELRQVNLQQFIQQTGTKVTVLPAEPIEIE 371
E+ + + ++++++E+E+ + +++R+ L++ +Q K+ + + E E
Sbjct: 404 RQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRE--LEEMMQDQEEKLREVEEKMQEEE 461
Query: 372 ASHADIERGI 381
+ E I
Sbjct: 462 EKMQEQEEKI 471
>gi|21735548 centrosomal protein 2 [Homo sapiens]
Length = 2442
Score = 65.5 bits (158), Expect = 8e-11
Identities = 78/335 (23%), Positives = 150/335 (44%), Gaps = 51/335 (15%)
Query: 66 WGQYA--SDVQLILRRTGPSLS-----ERPTSDSVARIPERTLY---RQSLPPLAKLRPQ 115
W Q A + +QL LR T L ++P + + A+ +LY +Q+L + + RP+
Sbjct: 1143 WAQEAKAAQLQLRLRSTESQLEALAAEQQPGNQAQAQAQLASLYSALQQALGSVCESRPE 1202
Query: 116 ID-------------------KSIKRREPKRKSLTFTGGAKGLMDIFGKGKETEFKQKVL 156
+ +S+ +R P +L+ A L + +T+ + VL
Sbjct: 1203 LSGGGDSAPSVWGLEPDQNGARSLFKRGPLLTALSAEAVASALHKLHQDLWKTQQTRDVL 1262
Query: 157 NNCKTTADELKKLIRLQTEK------LQSIEKQLESNEIEIRFWEQKYNSNLEEEIVRLE 210
+ +E +L + EK LQ +++QL N+ E WE K NS LE E++ L
Sbjct: 1263 RDQVQKLEE--RLTDTEAEKSQVHTELQDLQRQLSQNQEEKSKWEGKQNS-LESELMELH 1319
Query: 211 QKIKRNDVEIEEEEFWENELQIEQENEKQLKDQLQEIRQKITECENKLKDYLAQIRTMES 270
+ + + E E Q E+E LQ ++ +T L+ + + R S
Sbjct: 1320 ETMASLQSRLRRAELQRMEAQGERE-------LLQAAKENLTAQVEHLQAAVVEARAQAS 1372
Query: 271 --GLEAEKLQREVQEAQVNEEEVKGKIGKVKGEIDIQGQQSLRLENGIKAVERSLGQATK 328
G+ E L+ ++ EEV+ + + + +Q Q L++ G KA++ +L T+
Sbjct: 1373 AAGILEEDLRTARSALKLKNEEVESERERAQA---LQEQGELKVAQG-KALQENLALLTQ 1428
Query: 329 RLQDKEQELEQLTKELRQVNLQQFIQQTGTKVTVL 363
L ++E+E+E L +++++ Q+ +Q+ ++ L
Sbjct: 1429 TLAEREEEVETLRGQIQELEKQREMQKAALELLSL 1463
Score = 49.3 bits (116), Expect = 6e-06
Identities = 50/228 (21%), Positives = 105/228 (46%), Gaps = 26/228 (11%)
Query: 145 KGKETEFKQKVLNNCKTTADELKK--------------LIRLQTEKLQSIEKQLESNEIE 190
K KE E +Q+ ++ + D+L++ L+ + +++ +++QL+ +
Sbjct: 1734 KEKEVECQQEHIHELQELKDQLEQQLQGLHRKVGETSLLLSQREQEIVVLQQQLQEAREQ 1793
Query: 191 IRFWEQKYNSNLEEEIVRLEQKIKRNDVEIEEEEFWENELQIEQENEKQLKDQLQ----E 246
EQ S L+E ++ + + D E+E + + + Q ++E K+ D LQ +
Sbjct: 1794 GELKEQSLQSQLDE----AQRALAQRDQELEALQQEQQQAQGQEERVKEKADALQGALEQ 1849
Query: 247 IRQKITECENKLKDYLAQIRTMESGLEAEKLQREVQEAQVNEEEVKGKIGKVKGEIDIQG 306
+ E +L+D+ Q R +E L E + + E + + + + + K + +Q
Sbjct: 1850 AHMTLKERHGELQDHKEQARRLEEELAVEGRRVQALEEVLGDLRAESR-EQEKALLALQQ 1908
Query: 307 Q---QSLRLENGIKAVERSLGQATKRLQDKEQELEQLTKELRQVNLQQ 351
Q Q+ E +A++ S QA L++++QELE L E + Q+
Sbjct: 1909 QCAEQAQEHEVETRALQDSWLQAQAVLKERDQELEALRAESQSSRHQE 1956
Score = 47.8 bits (112), Expect = 2e-05
Identities = 48/215 (22%), Positives = 100/215 (46%), Gaps = 21/215 (9%)
Query: 155 VLNNCKTTADELKKLIRLQTEKLQSIEKQLESNEIEIRFWEQKYNSNLEEEIVRLEQKIK 214
+L + ++ +K+I+ E ++ LE+N E+ E + N +EE + L+Q IK
Sbjct: 291 LLTQSQKQNEDYEKMIKALRETVEI----LETNHTELMEHEASLSRNAQEEKLSLQQVIK 346
Query: 215 R-NDVEIEEEE------FWENELQIEQENEKQLKDQ-----LQEIRQKITECENKLKDYL 262
V +EE + EN L+++ Q Q L +R +T ++D
Sbjct: 347 DITQVMVEEGDNIAQGSGHENSLELDSSIFSQFDYQDADKALTLVRSVLTRRRQAVQDLR 406
Query: 263 AQIRTMESGLEAEKLQREVQEAQVNEEEVKGKIGKVKGEIDIQGQQSLRLENGIKAVERS 322
Q+ + + LQ++ + + + ++ ++ K+ GE D Q++ L+ + ++ +
Sbjct: 407 QQLAGCQEAVNL--LQQQHDQWEEEGKALRQRLQKLTGERDTLAGQTVDLQGEVDSLSKE 464
Query: 323 LGQATKRLQDKEQELEQLTKE---LRQVNLQQFIQ 354
K ++ Q+LE L +E LR+VN++ +Q
Sbjct: 465 RELLQKAREELRQQLEVLEQEAWRLRRVNVELQLQ 499
Score = 45.8 bits (107), Expect = 7e-05
Identities = 45/192 (23%), Positives = 84/192 (43%), Gaps = 15/192 (7%)
Query: 175 EKLQSIEKQLESNEIEIRFWEQKYNSNLEE--EIVRLEQKIKRNDVEIEEEEFW-ENELQ 231
++++ ++ QL + + R EQ+ L E E R++++++R + E L
Sbjct: 1010 KQVEDLKSQLVAQDDSQRLVEQEVQEKLRETQEYNRIQKELEREKASLTLSLMEKEQRLL 1069
Query: 232 IEQENEKQLKDQLQEIRQKITECENKLKDYLAQIRTMESGLEAEKLQREVQEAQVNEEEV 291
+ QE + + +L +RQ + E + + K+ AQ+ + ++ ++ QEAQ+ EE
Sbjct: 1070 VLQEADSIRQQELSALRQDMQEAQGEQKELSAQMELLRQEVKEKEADFLAQEAQLLEELE 1129
Query: 292 KGKIGKVKGEIDIQGQQSLRLENGIKAVERSLGQATKRLQDKEQELEQLTKELRQVNLQQ 351
I +Q LR + A E Q RL+ E +LE L E + N Q
Sbjct: 1130 ASHI----------TEQQLRA--SLWAQEAKAAQLQLRLRSTESQLEALAAEQQPGNQAQ 1177
Query: 352 FIQQTGTKVTVL 363
Q + + L
Sbjct: 1178 AQAQLASLYSAL 1189
Score = 45.4 bits (106), Expect = 9e-05
Identities = 48/213 (22%), Positives = 96/213 (45%), Gaps = 12/213 (5%)
Query: 154 KVLNNCKTTADELKKLIRLQTEKLQSIEKQLESNEIEIRFWEQKYNSNLEEEIVRLEQKI 213
K L + + EL+ ++ Q ++++I+ Q E + + E+E V L + +
Sbjct: 875 KALESLEREKMELEMRLKEQQTEMEAIQAQREEERTQAESALCQMQLETEKERVSLLETL 934
Query: 214 KRNDVEI----EEEEFWENELQI----EQENEKQLKDQLQEIRQKITECENKLKDYLAQI 265
+ E+ ++ E ++++ EQE L+ QLQE ++++ E + +D LA +
Sbjct: 935 LQTQKELADASQQLERLRQDMKVQKLKEQETTGILQTQLQEAQRELKEAARQHRDDLAAL 994
Query: 266 RTMESGLEAEK--LQREVQEAQVNEEEVKGKIGKVKGEIDIQGQQSLRLENGIKAVERSL 323
+ S L +K LQ++V++ + V+ E+ + +++ K +ER
Sbjct: 995 QEESSSLLQDKMDLQKQVEDLKSQLVAQDDSQRLVEQEVQEKLRETQEYNRIQKELEREK 1054
Query: 324 GQATKRLQDKEQELEQLTK--ELRQVNLQQFIQ 354
T L +KEQ L L + +RQ L Q
Sbjct: 1055 ASLTLSLMEKEQRLLVLQEADSIRQQELSALRQ 1087
Score = 44.7 bits (104), Expect = 1e-04
Identities = 56/270 (20%), Positives = 114/270 (42%), Gaps = 13/270 (4%)
Query: 81 GPSLSERPTSDSVARI-----PERTLYRQSLPPLAKLRPQIDKSIK--RREPKRKSLTFT 133
GPS ++R + + + I E ++ + L +L+ Q+++ ++ R+ SL +
Sbjct: 1715 GPSKAQRGSLEHMKLILRDKEKEVECQQEHIHELQELKDQLEQQLQGLHRKVGETSLLLS 1774
Query: 134 GGAKGLMDIFGKGKET----EFKQKVLNNCKTTADELKKLIRLQTEKLQSIEKQLESNEI 189
+ ++ + + +E E K++ L + A + E LQ ++Q + E
Sbjct: 1775 QREQEIVVLQQQLQEAREQGELKEQSLQSQLDEAQRALAQRDQELEALQQEQQQAQGQEE 1834
Query: 190 EIRFWEQKYNSNLEEEIVRLEQKIKRNDVEIEEEEFWENELQIEQENEKQLKDQLQEIRQ 249
++ LE+ + L+++ E+ E EL +E + L++ L ++R
Sbjct: 1835 RVKEKADALQGALEQAHMTLKERHGELQDHKEQARRLEEELAVEGRRVQALEEVLGDLRA 1894
Query: 250 KITECENKLKDYLAQI--RTMESGLEAEKLQREVQEAQVNEEEVKGKIGKVKGEIDIQGQ 307
+ E E L Q + E +E LQ +AQ +E ++ ++ E
Sbjct: 1895 ESREQEKALLALQQQCAEQAQEHEVETRALQDSWLQAQAVLKERDQELEALRAESQSSRH 1954
Query: 308 QSLRLENGIKAVERSLGQATKRLQDKEQEL 337
Q +A++ +LG+A LQ KEQ L
Sbjct: 1955 QEEAARARAEALQEALGKAHAALQGKEQHL 1984
Score = 41.2 bits (95), Expect = 0.002
Identities = 52/243 (21%), Positives = 109/243 (44%), Gaps = 39/243 (16%)
Query: 112 LRPQIDKSIKRREPKRKSLTFTGGAKGLMDIFGKGKETEFKQKV---LNNCKTTADELKK 168
LR QI + K+RE ++ +L +D+ + +E + +Q+ L C++ + L
Sbjct: 1440 LRGQIQELEKQREMQKAALELLS-----LDLKKRNQEVDLQQEQIQELEKCRSVLEHLPM 1494
Query: 169 LIRLQTEKLQSIEKQLESNEIEIRFWEQKYNSNLEEEIVRLEQKIKRNDVEIEEEEFWEN 228
++ + +KL +Q+ E + + + LE +++ LE+K D IE +
Sbjct: 1495 AVQEREQKLTVQREQIRELEKD----RETQRNVLEHQLLELEKK----DQMIESQRGQVQ 1546
Query: 229 ELQIEQENEKQLKDQLQEIRQKITECENKLKDYLAQIRTMESGLEAEKLQREVQEAQVNE 288
+L+ + + L +L+E K+ EC+ KL I+ +E QRE Q +
Sbjct: 1547 DLKKQLVTLECLALELEENHHKM-ECQQKL------IKELEG-------QRETQRVALTH 1592
Query: 289 EEVKGKIGKVKGEIDIQGQQSLRLENGIKAVERSLGQATKRLQDKEQELEQLTKELRQVN 348
+ + + E+ Q Q LE+ + R L Q+++QE++ +++ ++
Sbjct: 1593 LTLD--LEERSQELQAQSSQIHDLESHSTVLAREL-------QERDQEVKSQREQIEELQ 1643
Query: 349 LQQ 351
Q+
Sbjct: 1644 RQK 1646
Score = 40.4 bits (93), Expect = 0.003
Identities = 36/156 (23%), Positives = 72/156 (46%), Gaps = 7/156 (4%)
Query: 203 EEEIVRLEQKIKRNDVEIEEEEFWENELQIEQENEKQLKDQL----QEIRQKITECENKL 258
E ++LE +R+ E E + Q EQE + L+ Q +E+ Q + E +
Sbjct: 807 EVRCLKLELDTERSQAEQERDAAARQLAQAEQEGKTALEQQKAAHEKEVNQLREKWEKER 866
Query: 259 KDYLAQIRTMESGLEAEKLQRE--VQEAQVNEEEVKGKIGKVKGEID-IQGQQSLRLENG 315
+ ++ LE EK++ E ++E Q E ++ + + + + + Q L E
Sbjct: 867 SWHQQELAKALESLEREKMELEMRLKEQQTEMEAIQAQREEERTQAESALCQMQLETEKE 926
Query: 316 IKAVERSLGQATKRLQDKEQELEQLTKELRQVNLQQ 351
++ +L Q K L D Q+LE+L ++++ L++
Sbjct: 927 RVSLLETLLQTQKELADASQQLERLRQDMKVQKLKE 962
Score = 38.9 bits (89), Expect = 0.008
Identities = 41/200 (20%), Positives = 95/200 (47%), Gaps = 22/200 (11%)
Query: 166 LKKLIRLQTEKLQSIEKQLESNEIEIRFWE-QKYNSNLEEEIVRLEQKIKRNDVEIEEEE 224
L++ + L T+ L E+++E+ +I+ E Q+ E++ L+ K + +V++++E+
Sbjct: 1419 LQENLALLTQTLAEREEEVETLRGQIQELEKQREMQKAALELLSLDLKKRNQEVDLQQEQ 1478
Query: 225 FWENELQIEQENEKQLKDQLQEIRQKITECENKLKDYLAQIRTMESGLEAEKLQREVQEA 284
EL+ + + L +QE QK+T ++++ T + LE + L+ E ++
Sbjct: 1479 I--QELEKCRSVLEHLPMAVQEREQKLTVQREQIRELEKDRETQRNVLEHQLLELEKKDQ 1536
Query: 285 QVNEEEVKGKIGKVKGEI---------------DIQGQQSL--RLENGIKAVERSLGQAT 327
+ E +G++ +K ++ ++ QQ L LE + +L T
Sbjct: 1537 MI--ESQRGQVQDLKKQLVTLECLALELEENHHKMECQQKLIKELEGQRETQRVALTHLT 1594
Query: 328 KRLQDKEQELEQLTKELRQV 347
L+++ QEL+ + ++ +
Sbjct: 1595 LDLEERSQELQAQSSQIHDL 1614
Score = 35.4 bits (80), Expect = 0.089
Identities = 34/168 (20%), Positives = 69/168 (41%), Gaps = 16/168 (9%)
Query: 202 LEEEIVRLEQKIKRNDVEIEEEEFWENELQIEQ-----------ENEKQLKDQLQEIRQK 250
L +++++LE++ + +E E N LQ++ E L+ QLQ+ +
Sbjct: 615 LNQQLLQLEEENQSVCSRMEAAEQARNALQVDLAEAEKRREALWEKNTHLEAQLQKAEEA 674
Query: 251 ITECENKLKDYLAQIRTMESGLEAEKLQREVQEAQVNEEEVKGK-----IGKVKGEIDIQ 305
E + L+D + ++ L + Q+E Q+ + + K + + E +
Sbjct: 675 GAELQADLRDIQEEKEEIQKKLSESRHQQEAATTQLEQLHQEAKRQEEVLARAVQEKEAL 734
Query: 306 GQQSLRLENGIKAVERSLGQATKRLQDKEQELEQLTKELRQVNLQQFI 353
++ LE ++AVER ++LQ E L L + Q +
Sbjct: 735 VREKAALEVRLQAVERDRQDLAEQLQGLSSAKELLESSLFEAQQQNSV 782
Score = 33.9 bits (76), Expect = 0.26
Identities = 33/125 (26%), Positives = 59/125 (47%), Gaps = 23/125 (18%)
Query: 178 QSIEKQLESNEIEI-RFWEQKYNSNLEEEIVRLEQKIKRNDVEIEEEEFWENELQIEQEN 236
Q +EK+LE+ I + WE NL+E +VRLE++ +R + E +L++ E
Sbjct: 71 QELEKRLEATGGPIPQRWENVEEPNLDELLVRLEEEQQRCESLAEV----NTQLRLHMEK 126
Query: 237 EKQLKDQLQEIRQKITECENKLKDYLAQIRTMESGLEAEKLQREVQEAQVNEEEVKGKIG 296
+ L+E +K+T ++ +D +L R+ + Q+ +E KG +
Sbjct: 127 ADVVNKALREDVEKLTVDWSRARD---------------ELMRKESQWQMEQEFFKGYL- 170
Query: 297 KVKGE 301
KGE
Sbjct: 171 --KGE 173
Score = 33.5 bits (75), Expect = 0.34
Identities = 47/250 (18%), Positives = 101/250 (40%), Gaps = 48/250 (19%)
Query: 145 KGKETEFKQKVLNNCKTTADELKK-LIRLQTEKLQSIEKQLESNEIEIRFWEQKY----- 198
+G+ + ++VL + + + E +K L+ LQ Q +Q + +E+E R + +
Sbjct: 1878 EGRRVQALEEVLGDLRAESREQEKALLALQ----QQCAEQAQEHEVETRALQDSWLQAQA 1933
Query: 199 ---NSNLEEEIVRLEQKIKRNDVEIEEE----------------EFWENELQIEQENEKQ 239
+ E E +R E + R+ E + E L + E +
Sbjct: 1934 VLKERDQELEALRAESQSSRHQEEAARARAEALQEALGKAHAALQGKEQHLLEQAELSRS 1993
Query: 240 LKDQLQEIRQKITECENKLKDYLAQIRTMESGLEAEKLQ----------------REVQE 283
L+ ++ + C+ + +R E ++ + L+ E++
Sbjct: 1994 LEASTATLQASLDACQAHSRQLEEALRIQEGEIQDQDLRYQEDVQQLQQALAQRDEELRH 2053
Query: 284 AQVNEEEVKGKIGKVKGEIDIQGQQSL---RLENGIKAVERSLGQATKRLQDKEQELEQL 340
Q E+ ++ + + E IQ +Q+L R E I+ + +S+ + L KEQE+ +L
Sbjct: 2054 QQEREQLLEKSLAQRVQENMIQEKQNLGQEREEEEIRGLHQSVRELQLTLAQKEQEILEL 2113
Query: 341 TKELRQVNLQ 350
+ ++ NL+
Sbjct: 2114 RETQQRNNLE 2123
Score = 32.0 bits (71), Expect = 0.99
Identities = 38/169 (22%), Positives = 74/169 (43%), Gaps = 31/169 (18%)
Query: 214 KRNDVEIEEEEFWENELQIEQENE---KQLKDQLQEIRQKITECENKLKDYLAQIRTMES 270
K ++E E E + +Q++ + + +L+D++ E+ +T+ + + +DY I+ +
Sbjct: 252 KTQELEKEAHERSQELIQLKSQGDLEKAELQDRVTELSALLTQSQKQNEDYEKMIKALRE 311
Query: 271 GLE------------AEKLQREVQEAQVNEEEVKGKIGKV---KGEIDIQG---QQSLRL 312
+E L R QE +++ ++V I +V +G+ QG + SL L
Sbjct: 312 TVEILETNHTELMEHEASLSRNAQEEKLSLQQVIKDITQVMVEEGDNIAQGSGHENSLEL 371
Query: 313 ENGI----------KAVERSLGQATKRLQDKEQELEQLTKELRQVNLQQ 351
++ I KA+ T+R Q + +QL VNL Q
Sbjct: 372 DSSIFSQFDYQDADKALTLVRSVLTRRRQAVQDLRQQLAGCQEAVNLLQ 420
Score = 31.6 bits (70), Expect = 1.3
Identities = 40/183 (21%), Positives = 82/183 (44%), Gaps = 14/183 (7%)
Query: 164 DELKKLIRLQTEKLQSIEKQLESNEIEIRFWEQKYNSNLEEEIVRLEQKIKRNDVEIEEE 223
D L+ ++ + E+LQ+ +Q E+ EIE W +K +++ + K + ++E
Sbjct: 2142 DSLEPRLQRELERLQAALRQTEAREIE---WREK-----AQDLALSLAQTKASVSSLQEV 2193
Query: 224 EFWENELQIEQENEKQ-LKDQLQEIRQKITECENKLKDYLAQIRTMESGLEAEKLQREVQ 282
+ +E+++E+Q L+D+L+ R+ + E + T E G E+ + +
Sbjct: 2194 AMFLQASVLERDSEQQRLQDELELTRRAL---EKERLHSPGATSTAELGSRGEQGVQLGE 2250
Query: 283 EAQVNEEEVKGKIGKV--KGEIDIQGQQSLRLENGIKAVERSLGQATKRLQDKEQELEQL 340
+ V E + K + ++ Q RLE ++R Q L+ E+E +L
Sbjct: 2251 VSGVEAEPSPDGMEKQSWRQRLEHLQQAVARLEIDRSRLQRHNVQLRSTLEQVERERRKL 2310
Query: 341 TKE 343
+E
Sbjct: 2311 KRE 2313
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 65.5 bits (158), Expect = 8e-11
Identities = 44/187 (23%), Positives = 103/187 (55%), Gaps = 9/187 (4%)
Query: 165 ELKKLIRLQTEKLQSIEK---QLESNEIEIRFWEQKYNSNLEEEIVRLEQKIKRNDVEIE 221
E ++ IR EK+ EK Q E + E + EQ+ E ++ R E+KI+ + +I
Sbjct: 341 EKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIR 400
Query: 222 EEE--FWENELQIEQENEK--QLKDQLQEIRQKITECENKLKDYLAQIRTMESGLEAEKL 277
E+E E E ++ ++ EK + ++++QE +K+ E K+++ +IR E + ++
Sbjct: 401 EQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEE 460
Query: 278 QREVQEAQVNEEEVKGKIGKVKGEIDIQGQQSLRLENGIKAVERSLGQATKRLQDKEQEL 337
+ QE ++ E+E GK+ + + ++ Q ++ R E I+ E+ + + ++++++E+ +
Sbjct: 461 MMQEQEEKMGEQE--GKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMM 518
Query: 338 EQLTKEL 344
++ +++
Sbjct: 519 QEQEEKM 525
Score = 60.1 bits (144), Expect = 3e-09
Identities = 48/184 (26%), Positives = 95/184 (51%), Gaps = 19/184 (10%)
Query: 173 QTEKLQSIEKQLESNEIEIRFWEQKYNSNLEEEIVRLEQKIKRNDVEIEEEEFWENELQI 232
Q EK+Q E++++ E +IR E+K EE + E+K++R +EE WE E +I
Sbjct: 293 QEEKIQEREEKIQEQEEKIREQEEKMRRQ-EEMMWEKEEKMRR-----QEEMMWEKEEKI 346
Query: 233 --------EQENEKQLKDQLQEIRQKITECENKLKDYLAQIRTMESGLEAEKLQREVQEA 284
EQE ++ +++ QE +KI E E + + R E E E+ RE +E
Sbjct: 347 RELEEKMHEQEKIREQEEKRQE-EEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEM 405
Query: 285 QVNEEEVKG----KIGKVKGEIDIQGQQSLRLENGIKAVERSLGQATKRLQDKEQELEQL 340
+EE G K+ + + E+ Q ++ R E I+ E+ + + ++++++E+ +++
Sbjct: 406 MQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQ 465
Query: 341 TKEL 344
+++
Sbjct: 466 EEKM 469
Score = 57.0 bits (136), Expect = 3e-08
Identities = 55/251 (21%), Positives = 118/251 (47%), Gaps = 13/251 (5%)
Query: 104 QSLPPLAKLRPQIDKSIKRREPKRKSLTFTGGAKGLMDIFGKGKETEFKQKVLNNCKTTA 163
Q+L +A + + D+ I+ +R +L+ + D K K + ++K L ++
Sbjct: 167 QALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEK-LQLVESEK 225
Query: 164 DELKKLIRLQTEKLQSIEKQLESNEIEIRFWEQKYNSNLEEEIVRLEQKIKRNDVEIEEE 223
E++ ++ KL+ + L ++ Q +L +E+ + K++ ++EE
Sbjct: 226 SEIQLNVKELKRKLERAKLLLPQQQL------QAEADHLGKELQSVSAKLQ---AQVEEN 276
Query: 224 EFWENELQIEQENEKQLKDQLQEIRQKITECENKLKDYLAQIRTMESGL--EAEKLQREV 281
E W Q ++E + ++++QE +KI E E K+++ ++R E + + EK++R+
Sbjct: 277 ELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQE 336
Query: 282 QEAQVNEEEVKGKIGKVKGEIDIQGQQSLRL-ENGIKAVERSLGQATKRLQDKEQELEQL 340
+ EE+++ K+ + I+ Q+ R E I+ E+ Q K + +E+ EQ
Sbjct: 337 EMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQE 396
Query: 341 TKELRQVNLQQ 351
K Q + Q
Sbjct: 397 EKIREQEEMMQ 407
Score = 57.0 bits (136), Expect = 3e-08
Identities = 44/224 (19%), Positives = 108/224 (48%), Gaps = 33/224 (14%)
Query: 165 ELKKLIRLQTEKLQSIEKQLESNEIEIR-----FWEQKYNSNLEEEIVRLEQKIKRNDVE 219
E ++ IR Q EK++ E+ + E ++R WE++ EE + ++KI+ + +
Sbjct: 306 EQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEK 365
Query: 220 IEEEE--------------FWENELQIEQENEK--QLKDQLQEIRQKITECENKLKDYLA 263
+EEE W E +I ++ EK + ++ +QE +K+ E E K+ +
Sbjct: 366 RQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEE 425
Query: 264 QIRTMESGLEAEKLQREVQEAQVNEEEVK------------GKIGKVKGEIDIQGQQSLR 311
+++ E + ++ + QE ++ E+E K K+G+ +G++ Q +
Sbjct: 426 EMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQE 485
Query: 312 LENGIKAVERSLGQATKRLQDKEQELEQLTKELRQVNLQQFIQQ 355
E ++ E + + K+++++E+++ + + +++ + + Q+
Sbjct: 486 QEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQE 529
Score = 52.4 bits (124), Expect = 7e-07
Identities = 48/187 (25%), Positives = 98/187 (52%), Gaps = 30/187 (16%)
Query: 165 ELKKLIRLQTEKLQSIEKQLESNEIEIRFWEQKYN-SNLEEEIVRLEQKIKRNDVEI--E 221
E ++ IR Q E +Q E+++ E E + WEQ+ EE++ R E+KI+ + +I +
Sbjct: 394 EQEEKIREQEEMMQEQEEKM--GEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQ 451
Query: 222 EEEFWENELQIEQENEK-------------QLKDQLQEIR---QKITECENKLKDYLAQI 265
EE+ E E ++++ EK ++++Q +++R +KI E E K+++ +I
Sbjct: 452 EEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKI 511
Query: 266 RTMESGLEAEKLQREVQEAQVNEEEVKGKIGKVKGEIDIQGQQSLRLENGIKAVERSLGQ 325
R E E++ +E +E +EE K+ + + ++ Q ++ R E ++ E L Q
Sbjct: 512 R------EQEEMMQEQEEKMWEQEE---KMCEQEEKMQEQEEKMRRQEEKMREQEVRLRQ 562
Query: 326 ATKRLQD 332
+++Q+
Sbjct: 563 QEEKMQE 569
Score = 39.7 bits (91), Expect = 0.005
Identities = 27/154 (17%), Positives = 73/154 (47%), Gaps = 4/154 (2%)
Query: 197 KYNSNLEEEIVRLEQKIKRNDVEIEEEEFWENELQIEQENEKQLKDQLQEIRQKITE--- 253
K+ LE+ + + + K+ D IEE + L +E ++L+E K+ E
Sbjct: 160 KFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQ 219
Query: 254 -CENKLKDYLAQIRTMESGLEAEKLQREVQEAQVNEEEVKGKIGKVKGEIDIQGQQSLRL 312
E++ + ++ ++ LE KL Q+ Q + + ++ V ++ Q +++
Sbjct: 220 LVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELW 279
Query: 313 ENGIKAVERSLGQATKRLQDKEQELEQLTKELRQ 346
+ E + + +++Q++E+++++ +++R+
Sbjct: 280 NRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIRE 313
Score = 38.1 bits (87), Expect = 0.014
Identities = 42/195 (21%), Positives = 93/195 (47%), Gaps = 37/195 (18%)
Query: 98 ERTLYRQSLPPLAKLRPQIDKSIKRREPKRKSLTFTGGAKGLMDIFGKGKETEFKQKVLN 157
E ++RQ K+R Q +K ++ E ++ G + M + + +E + +++ +
Sbjct: 382 EAKMWRQE----EKIREQEEKIREQEEMMQEQEEKMGEQEEKM--WEQEEEMQEQEEKMR 435
Query: 158 NCKTTADELKKLIRLQTEKLQSIEKQLESNEI------------EIRFWEQKYNSNLEEE 205
+ E +K IR Q EK++ E+ ++ E E + EQ+ +EE
Sbjct: 436 RQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEE 495
Query: 206 IVR-LEQKIKRNDVEI---------EEEEFWENELQI------EQENEKQLKDQLQEIRQ 249
+R E+KI+ + +I +EE+ WE E ++ QE E++++ Q +++R+
Sbjct: 496 KIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMRE 555
Query: 250 ---KITECENKLKDY 261
++ + E K++++
Sbjct: 556 QEVRLRQQEEKMQEH 570
>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 436
Score = 63.9 bits (154), Expect = 2e-10
Identities = 45/185 (24%), Positives = 100/185 (54%), Gaps = 15/185 (8%)
Query: 173 QTEKLQSIEKQLESNEIEIRFWEQKYNSNLEEEIVRLEQKIKRNDVEI--EEEEFWENEL 230
Q E++Q E+Q+ E ++R E++ EE++ + E+++++ + ++ +EE+ E E
Sbjct: 211 QEEQMQKQEEQMGEQEEQMRKQEEQMGEQ-EEQVQKQEEQVQKQEEQMRKQEEQMREQEE 269
Query: 231 QIEQENEKQLKDQLQEIRQKITECENKLKDYLAQIRTMESGLEAEKLQREVQEAQVNEEE 290
Q+ ++ E+ LK + Q TE E + + Q+R E + ++ Q QE Q+ E+E
Sbjct: 270 QMREQEEQMLKQKEQ------TEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQE 323
Query: 291 VKGKIGKVKGEIDIQGQQSLRLENGIKAVERSLGQATKRLQDKEQEL----EQLTKELRQ 346
++GK + ++ Q +Q + + E +G+ +++Q +E+++ EQ+ K+ Q
Sbjct: 324 --EQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQ 381
Query: 347 VNLQQ 351
+ Q+
Sbjct: 382 MRKQE 386
Score = 58.2 bits (139), Expect = 1e-08
Identities = 49/221 (22%), Positives = 113/221 (51%), Gaps = 16/221 (7%)
Query: 146 GKETEFKQKVLNNCKTTADELKKL---IRLQTEKLQSIEKQLESNEIEIRFWEQKYNSNL 202
G++ E QK ++++K + Q E++Q E+Q++ E ++R E++
Sbjct: 209 GEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQE 268
Query: 203 EEEIVRLEQKIKRNDVEIEEEEFWENELQIEQENE--KQLKDQLQEIRQKITECENKLKD 260
E+ + EQ +K+ + +EE+ E E Q+ ++ E ++ ++Q++E +++ E E ++
Sbjct: 269 EQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGK 328
Query: 261 YLAQIRTMESGLEAEKLQREVQEAQVNEEEVK-----GKIGKVKGEIDIQGQQSLRLENG 315
Q+ + + +K Q QE Q+ E+E + ++ K + ++ Q +Q + E
Sbjct: 329 QEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQ 388
Query: 316 IKAVERSLGQATKRL-----QDKEQELEQLTKELRQVNLQQ 351
++ E +G+ +++ Q +EQE EQ+ ++ Q+ Q+
Sbjct: 389 MRKQEEQMGEQKEQMGEQKEQMREQE-EQMGEQKEQMRKQE 428
Score = 56.6 bits (135), Expect = 4e-08
Identities = 46/201 (22%), Positives = 103/201 (51%), Gaps = 16/201 (7%)
Query: 165 ELKKLIRLQTEKLQSIEKQLESNEIEIRFWEQKYNSNLEEEIVRLEQKIKRNDVEIEEEE 224
E K+ Q +++ E Q+ E ++R E + E ++ E +++ + ++ E+E
Sbjct: 42 ETDKIPLPQEGQVREQEGQVREQEGQVREQEGQVREQ-EGQVREQEGQVREQEGQVREQE 100
Query: 225 --FWENELQIEQENEKQLKDQLQEIRQK---ITECENKLKDYLAQIRTMESGLEAEKLQR 279
E E Q+ +E E Q+++Q ++R++ + E E ++++ Q+R E + ++ Q
Sbjct: 101 GQVREQEGQV-REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQV 159
Query: 280 EVQEAQVNEE-----EVKGKIGKVKGEIDIQGQQSLRLENGIKAVERSLGQATKRLQDKE 334
QE QV E+ E +G++ + +G++ Q Q E + E +G+ +++Q +E
Sbjct: 160 REQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQE 219
Query: 335 QEL----EQLTKELRQVNLQQ 351
+++ EQ+ K+ Q+ Q+
Sbjct: 220 EQMGEQEEQMRKQEEQMGEQE 240
Score = 52.8 bits (125), Expect = 5e-07
Identities = 42/191 (21%), Positives = 92/191 (48%), Gaps = 14/191 (7%)
Query: 147 KETEFKQKVLNNCKTTADELKKLIRLQTEKLQSIEKQLESNEIEIRFWEQKYNSNLEEEI 206
K+ E QK + +++++ E+ + + KQ E E E + EQ+ +EE
Sbjct: 245 KQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQ 304
Query: 207 VRLEQKIKRNDVE----------IEEEEFWENELQIEQENEKQLK--DQLQEIRQKITEC 254
+R +++ R E +EE+ WE + Q+ ++ E+ K +Q+ E +++ +
Sbjct: 305 MREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQ 364
Query: 255 ENKLKDYLAQIRTMESGLEAEKLQREVQEAQVNEEEVKGKIGKVKGEIDIQGQQSLRLEN 314
E +++ Q+R E + ++ Q QE Q+ E+ K ++G+ K ++ Q +Q +
Sbjct: 365 EEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQ--KEQMGEQKEQMREQEEQMGEQKE 422
Query: 315 GIKAVERSLGQ 325
++ E +G+
Sbjct: 423 QMRKQEEHMGE 433
Score = 50.4 bits (119), Expect = 3e-06
Identities = 41/177 (23%), Positives = 97/177 (54%), Gaps = 12/177 (6%)
Query: 171 RLQTEKLQSIEKQLESNEIEIRFWEQKYNSNLEEEIVRLEQKIKRNDVEIEEE-EFWENE 229
R+ E+L+ EK E E E++ E + S ++ I L++K++ + + + +E + E E
Sbjct: 3 RITNEELK--EKNAELQE-ELQLVETE-KSEIQLHIKELKRKLETDKIPLPQEGQVREQE 58
Query: 230 LQIEQENEKQLKDQLQEIRQKITECENKLKDYLAQIRTMESGLEAEKLQREVQEAQVNEE 289
Q+ +E E Q+++Q ++R++ E ++++ Q+R E + ++ Q QE QV E+
Sbjct: 59 GQV-REQEGQVREQEGQVREQ----EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 113
Query: 290 EVKGKIGKVKGEIDIQGQQSLRLENGIKAVERSLGQATKRLQDKEQELEQLTKELRQ 346
E G++ + +G++ Q Q E ++ E + + +++++E ++ + ++R+
Sbjct: 114 E--GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVRE 168
Score = 48.5 bits (114), Expect = 1e-05
Identities = 41/188 (21%), Positives = 103/188 (54%), Gaps = 15/188 (7%)
Query: 170 IRLQTEKLQSIEKQLESNEIEIRFWEQKYNSNLEEEIVRLEQKIKRNDVEI--EEEEFWE 227
+R Q +++ E Q+ E ++ E++ EE++ + E+++ + ++ +EE+ E
Sbjct: 180 VREQEGQVREQEGQMGEQEGQMGEQEEQMGEQ-EEQMQKQEEQMGEQEEQMRKQEEQMGE 238
Query: 228 NELQIEQENEKQLKDQLQEIRQKITECENKLKDYLAQIRTMESGLEAEKLQREVQEAQVN 287
E Q+ Q+ E+Q++ Q +++R++ E ++++ Q+R E + +K Q E QE Q
Sbjct: 239 QEEQV-QKQEEQVQKQEEQMRKQ----EEQMREQEEQMREQEEQMLKQKEQTE-QEEQTG 292
Query: 288 EEEVKGKIGKVKGEIDIQGQQSLRLENGIKAVERSLGQATKRLQDKEQEL----EQLTKE 343
E+E ++ + + ++ Q +Q E ++ E +G+ +++ ++++++ EQ+ K+
Sbjct: 293 EQE--EQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQ 350
Query: 344 LRQVNLQQ 351
Q+ Q+
Sbjct: 351 EEQMGEQE 358
Score = 43.5 bits (101), Expect = 3e-04
Identities = 29/159 (18%), Positives = 81/159 (50%), Gaps = 16/159 (10%)
Query: 145 KGKETEFKQKVLNNCKTTADELKKLIRLQTEKLQSIEKQLESNEIEI-----RFWEQKYN 199
K KE +++ + E ++ +R Q E+++ E+Q+ E ++ + WEQK
Sbjct: 280 KQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQ 339
Query: 200 S--------NLEEEIVRLEQKIKRNDVEIEEEEFWENELQIEQENEKQLKDQLQEIRQKI 251
EE++ E+++++ + ++ ++ E +++ ++E ++ ++Q+++ +++
Sbjct: 340 MWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQ---EEQMRKQEEQMRKQEEQMRKQEEQM 396
Query: 252 TECENKLKDYLAQIRTMESGLEAEKLQREVQEAQVNEEE 290
E + ++ + Q+R E + +K Q QE + E++
Sbjct: 397 GEQKEQMGEQKEQMREQEEQMGEQKEQMRKQEEHMGEQK 435
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 62.8 bits (151), Expect = 5e-10
Identities = 41/177 (23%), Positives = 96/177 (54%), Gaps = 13/177 (7%)
Query: 170 IRLQTEKLQSIEKQLESNEIEIRFWEQKYNSNLEEEIVRLEQKIKRNDVEIEEEEFWENE 229
IR Q E + EK E +I WE++ E+++ R E+KI+ +EE+ W E
Sbjct: 540 IREQEEMWREEEKMHEQEKI----WEEEKRQEQEDKMWRQEEKIRE-----QEEKVWRQE 590
Query: 230 LQIEQENEK--QLKDQLQEIRQKITECENKLKDYLAQIRTMESGLEAEKLQREVQEAQVN 287
+I ++ EK + ++++ + +KI E E K+++ +IR E + ++ + QE ++
Sbjct: 591 EKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMG 650
Query: 288 EEEVKGKIGKVKGEIDIQGQQSLRLENGIKAVERSLGQATKRLQDKEQELEQLTKEL 344
E+E K+ + + ++ Q + R E I+ E+ + + ++++++E+ +++ +++
Sbjct: 651 EQE--EKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKM 705
Score = 62.0 bits (149), Expect = 9e-10
Identities = 45/208 (21%), Positives = 111/208 (53%), Gaps = 18/208 (8%)
Query: 147 KETEFKQKVLNNCKTTADELKKLIRLQTEKLQSIEKQLESNEIEIR-----FWEQKYNSN 201
+E +Q+ + K E ++ IR Q EK+ E+++ E +IR W Q+
Sbjct: 482 EEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIR 541
Query: 202 LEEEIVRLEQKIKRNDVEIEEEEFWENELQIEQENEK-QLKDQLQEIRQKITECENKLKD 260
+EE+ R E+K+ E+E+ WE E + EQE++ + +++++E +K+ E K+++
Sbjct: 542 EQEEMWREEEKMH------EQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIRE 595
Query: 261 YLAQIRTMESGL--EAEKLQREVQEAQVNEEEVKGKIGKVKGEIDIQGQQSLRLENGIKA 318
+ + E + + EK++ + ++ Q EE+++ + K++ + ++ +Q E +
Sbjct: 596 QEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQ----EEKMGE 651
Query: 319 VERSLGQATKRLQDKEQELEQLTKELRQ 346
E + + +++Q++E+ + + +++R+
Sbjct: 652 QEEKMCEQEEKMQEQEETMWRQEEKIRE 679
Score = 55.1 bits (131), Expect = 1e-07
Identities = 52/203 (25%), Positives = 101/203 (49%), Gaps = 24/203 (11%)
Query: 173 QTEKLQSIEKQLESNEIEIRFWEQKYNSNLEEEIVRLEQKI--KRNDVEIEEEEFWENEL 230
Q EK+Q E++++ E +IR E+K EE++ R E+ + K + +EE WE E
Sbjct: 305 QEEKIQEWEEKIQEQEEKIREQEEKIREQ-EEKMRRQEEMMWEKEEKMRRQEEMMWEKEE 363
Query: 231 QIEQENE---------KQLKDQLQEIRQKITECENKLKDYLAQIRTMESGLEAEKLQ--- 278
++ ++ E ++ ++ + E +KI E E K+ + E E EK++
Sbjct: 364 KMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQE 423
Query: 279 -REVQEAQVNEEEVKGKIGKVKGEIDIQGQQSLRLENGIKAVERSLGQATKRLQDKEQEL 337
R+ QEA++ +E KI + + +I Q ++ R E I E+ R ++K QE
Sbjct: 424 KRQEQEAKMWRQE--EKIREQEEKIREQEKKMWRQEEKIHEQEKI------REEEKRQEQ 475
Query: 338 EQLTKELRQVNLQQFIQQTGTKV 360
E++ ++ +++ Q+ I + K+
Sbjct: 476 EEMWRQEEKIHEQEEIWRQKEKM 498
Score = 53.9 bits (128), Expect = 2e-07
Identities = 42/182 (23%), Positives = 92/182 (50%), Gaps = 19/182 (10%)
Query: 173 QTEKLQSIEKQLESNEIEIRFWEQKYNSNLEEEIVRLEQKIKRNDVEIEEEEFWENELQI 232
Q EK++ E+++ E E + W Q EE + ++KI+ + E+EE W E +I
Sbjct: 435 QEEKIREQEEKIR--EQEKKMWRQ-------EEKIHEQEKIREEEKRQEQEEMWRQEEKI 485
Query: 233 EQENE-----KQLKDQLQEIR---QKITECENKLKDYLAQIRTMESGLEAEKLQREVQEA 284
++ E +++ +Q ++IR +K+ E K+++ +IR E + ++ + QE
Sbjct: 486 HEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEE 545
Query: 285 QVNEEEVKGKIGKVKGEIDIQGQQS--LRLENGIKAVERSLGQATKRLQDKEQELEQLTK 342
EEE + K+ E Q Q+ R E I+ E + + ++++++E++ ++ +
Sbjct: 546 MWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEE 605
Query: 343 EL 344
++
Sbjct: 606 KM 607
Score = 50.8 bits (120), Expect = 2e-06
Identities = 48/244 (19%), Positives = 118/244 (48%), Gaps = 21/244 (8%)
Query: 104 QSLPPLAKLRPQIDKSIKRREPKRKSLTFTGGAKGLMDIFGKGKETEFKQKVLNNCKTTA 163
Q+L +A + + D+ I+ +R +L+ + D K K + ++K L ++
Sbjct: 179 QALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEK-LQLVESEK 237
Query: 164 DELKKLIRLQTEKLQSIEKQLESNEIEIRFWEQKYNSNLEEEIVRLEQKIKRNDVEIEEE 223
E++ ++ KL+ + L ++ Q +L +E+ + K++ ++EE
Sbjct: 238 SEIQLNVKELKRKLERAKLLLPQQQL------QAEADHLGKELQSVSAKLQ---AQVEEN 288
Query: 224 EFWENELQIEQENEKQLKDQLQEIRQKITECENKLKDYLAQIRTMESGLEAEKLQREVQE 283
E W Q ++E + ++++QE +KI E E K+++ +IR E EK++R+ +
Sbjct: 289 ELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQE-----EKMRRQEEM 343
Query: 284 AQVNEEEVKGKIGKV-KGEIDIQGQQSLRLENGIKAVERSLGQATKRLQDKEQELEQLTK 342
EE+++ + + + E ++ Q+ + E E + + + + +KE+++ +L +
Sbjct: 344 MWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEK-----EEKMRRQEEMMWEKEEKIRELEE 398
Query: 343 ELRQ 346
++ +
Sbjct: 399 KMHE 402
Score = 50.1 bits (118), Expect = 4e-06
Identities = 35/128 (27%), Positives = 74/128 (57%), Gaps = 7/128 (5%)
Query: 170 IRLQTEKLQSIEKQLESNEIEIRFWEQKYNSNLEEEIVRLEQKIKRNDVEIEEEE--FWE 227
IR Q EK+Q E+++ E +IR E+ EE++ E+K+ + +++E+E W
Sbjct: 614 IREQEEKIQEQEEKIREQEEKIREQEEMTQEQ-EEKMGEQEEKMCEQEEKMQEQEETMWR 672
Query: 228 NELQIEQENEKQLKDQLQEIRQK---ITECENKLKDYLAQIRTMESGLEAEKLQREVQEA 284
E +I +E EK++++Q ++IR++ + E E K+ + ++ E ++ ++ + QE
Sbjct: 673 QEEKI-REQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEE 731
Query: 285 QVNEEEVK 292
++ E+EV+
Sbjct: 732 KMWEQEVR 739
Score = 49.7 bits (117), Expect = 5e-06
Identities = 50/200 (25%), Positives = 102/200 (51%), Gaps = 12/200 (6%)
Query: 152 KQKVLNNCKTTADELKKLIRLQTEKLQSIEK---QLESNEIEIRFWEQKYNSNLEEEIVR 208
K++ + + E +K IR Q EK Q EK Q + E E + W Q+ +EE +R
Sbjct: 389 KEEKIRELEEKMHEQEK-IREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIR 447
Query: 209 -LEQKIKRNDVEI-EEEEFWENELQIEQENEKQLKDQLQEIRQKITECENKLKDYLAQIR 266
E+K+ R + +I E+E+ E E + EQE + ++++ E +++I + K+ + +IR
Sbjct: 448 EQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHE-QEEIWRQKEKMHEQEEKIR 506
Query: 267 TMESGLEAEKLQREVQEAQVNEEEVKGKIGKVKGEIDIQGQQSLRLENGIKAVERSLGQA 326
E + ++ + QE ++ E+E K + E I+ Q+ + E + + +
Sbjct: 507 KQEEKVWRQEEKIREQEEKIREQEEK----MWRQEEKIREQEEMWREEEKMHEQEKIWEE 562
Query: 327 TKRLQDKEQELEQLTKELRQ 346
KR Q++E ++ + +++R+
Sbjct: 563 EKR-QEQEDKMWRQEEKIRE 581
Score = 49.3 bits (116), Expect = 6e-06
Identities = 51/192 (26%), Positives = 92/192 (47%), Gaps = 14/192 (7%)
Query: 165 ELKKLIRLQTEKLQSIEK---QLESNEIEIRFWEQKYNSNLEEEIVRLEQKIKRNDVEIE 221
E ++ IR EK+ EK Q E + E + EQ+ E ++ R E+KI+ + +I
Sbjct: 388 EKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIR 447
Query: 222 EEE--FWENELQIEQENEKQLKDQLQEIRQKITECENKLKDYLAQIRTMESGLEAEKLQR 279
E+E W E +I E EK +++ ++ ++++ E K+ + R E E E+ R
Sbjct: 448 EQEKKMWRQEEKI-HEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIR 506
Query: 280 EVQEAQVNEEEVKGKIGKVKGEIDIQGQQSLRLENGIKAVERSLGQATK-----RLQDKE 334
+ +E +EE KI + + +I Q ++ R E I+ E + K ++ ++E
Sbjct: 507 KQEEKVWRQEE---KIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEE 563
Query: 335 QELEQLTKELRQ 346
+ EQ K RQ
Sbjct: 564 KRQEQEDKMWRQ 575
Score = 45.1 bits (105), Expect = 1e-04
Identities = 47/188 (25%), Positives = 101/188 (53%), Gaps = 28/188 (14%)
Query: 175 EKLQSIEKQLESNEIEIRFWEQKYNSNLEEEIVRLEQKIKRNDVEI--EEEEFWENELQI 232
EK++ +E+++ E +IR E+K EEE +R ++K + + ++ +EE+ E E +I
Sbjct: 391 EKIRELEEKMHEQE-KIREQEEKRQ---EEEKIREQEKRQEQEAKMWRQEEKIREQEEKI 446
Query: 233 EQENEKQLKDQLQEIRQKITECENKLKDYLAQIRTMESGLEAEKLQREVQEAQVNEEE-- 290
+E EK++ Q ++I ++ +IR E E E++ R QE +++E+E
Sbjct: 447 -REQEKKMWRQEEKIHEQ------------EKIREEEKRQEQEEMWR--QEEKIHEQEEI 491
Query: 291 --VKGKIGKVKGEIDIQGQQSLRLENGIKAVERSLGQATKRL---QDKEQELEQLTKELR 345
K K+ + + +I Q ++ R E I+ E + + +++ ++K +E E++ +E
Sbjct: 492 WRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEE 551
Query: 346 QVNLQQFI 353
+++ Q+ I
Sbjct: 552 KMHEQEKI 559
Score = 44.7 bits (104), Expect = 1e-04
Identities = 30/130 (23%), Positives = 70/130 (53%), Gaps = 9/130 (6%)
Query: 165 ELKKLIRLQTEKLQSIEKQLESNEIEIRFWEQKY------NSNLEEEIVRLEQKIKRNDV 218
E ++ IR Q EK++ E+ + E ++ E+K EE + R E+KI+ +
Sbjct: 623 EQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEK 682
Query: 219 EIEEEEFWENELQIEQENEKQLKDQLQEIRQKITECENKLKDYLAQIRTMESGLEAEKLQ 278
+I E+ E +++ ++E ++ ++++ E +K+ E E K+++ ++R E + ++++
Sbjct: 683 KIREQ---EEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVR 739
Query: 279 REVQEAQVNE 288
QE ++ E
Sbjct: 740 LRQQEEKMQE 749
Score = 37.7 bits (86), Expect = 0.018
Identities = 27/154 (17%), Positives = 72/154 (46%), Gaps = 4/154 (2%)
Query: 197 KYNSNLEEEIVRLEQKIKRNDVEIEEEEFWENELQIEQENEKQLKDQLQEIRQKITE--- 253
K+ LE+ + + + K+ D IEE + L +E ++L+E K+ E
Sbjct: 172 KFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQ 231
Query: 254 -CENKLKDYLAQIRTMESGLEAEKLQREVQEAQVNEEEVKGKIGKVKGEIDIQGQQSLRL 312
E++ + ++ ++ LE KL Q+ Q + + ++ V ++ Q +++
Sbjct: 232 LVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELW 291
Query: 313 ENGIKAVERSLGQATKRLQDKEQELEQLTKELRQ 346
+ E + + +++Q+ E+++++ +++R+
Sbjct: 292 NRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIRE 325
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 62.8 bits (151), Expect = 5e-10
Identities = 51/247 (20%), Positives = 128/247 (51%), Gaps = 23/247 (9%)
Query: 103 RQSLPPLAKLRPQIDKSIKRREPKRKSLTFTGGAKGLMDIFGKGKETEFKQKVLNNCKTT 162
+++L ++ + D+ I+ +R +L+ + + K K E ++K L ++
Sbjct: 144 QRALSAVSTWHKKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEK-LRLAESE 202
Query: 163 ADELK---KLIRLQTEKLQSIEKQLESNEIEIRFWEQKYNSNLEEEIVRLEQKIKRNDVE 219
E++ K ++ + E+ + + Q+++N ++ W Q EEE+ E+KI++
Sbjct: 203 KSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQ------EEELREQEKKIRK---- 252
Query: 220 IEEEEFWENELQIEQENEKQLKDQLQEIRQKITECENKLKDYLAQIRTMESGLEAEKLQR 279
+EE+ W E ++ +E E ++++Q +++R++ E +L++ ++R E L +K R
Sbjct: 253 -QEEKMWRQEERL-REQEGKMREQEEKMRRQ----EKRLREQEKELREQEKELREQKKLR 306
Query: 280 EVQEAQVNEEEVKGKIGKVKGEIDIQGQQSLRLENGIKAVERSLGQATKRLQDKEQELEQ 339
E +E +EE K+ + + ++ Q ++ R E + E+ + + ++++D+E+ + +
Sbjct: 307 EQEEQMQEQEE---KMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWE 363
Query: 340 LTKELRQ 346
+ LR+
Sbjct: 364 QDERLRE 370
Score = 60.5 bits (145), Expect = 3e-09
Identities = 40/186 (21%), Positives = 105/186 (56%), Gaps = 19/186 (10%)
Query: 165 ELKKLIRLQTEKLQSIEKQLESNEIEIRFWEQKYNSNLEEEIV-----RLEQKIKRNDVE 219
E ++++R Q EK+Q E+++ E E + WEQ+ +EE + ++ ++ + + ++
Sbjct: 571 EEEEMMREQEEKMQEQEEKMR--EQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQ 628
Query: 220 IEEEEFWENELQIEQENEK--QLKDQLQEIRQKITECENKLKDYLAQIRTMESGLEAEKL 277
+EE WE E +++++ EK + +++++E +K+ E E K++ ++R E EK+
Sbjct: 629 EQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQE-----EKM 683
Query: 278 QREVQEAQVNEEEVKGKIGKVKGEIDIQGQQSLRLENGIKAVERSLGQATKRLQDKEQEL 337
Q + ++ + EE+++G+ K+ G+ + Q ++ + + + +R++D+++++
Sbjct: 684 QGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWG-----QEEMREKEERIRDQKEKM 738
Query: 338 EQLTKE 343
++ E
Sbjct: 739 QERLPE 744
Score = 57.0 bits (136), Expect = 3e-08
Identities = 45/194 (23%), Positives = 106/194 (54%), Gaps = 8/194 (4%)
Query: 165 ELKKLIRLQTEKLQSIEKQLESNEIEIRFWEQKYNSNLEEEIVRLEQKIKRNDVEI-EEE 223
E +K IR Q EK+ E++L E ++R E+K E+ + E++++ + E+ E++
Sbjct: 245 EQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQ-EKRLREQEKELREQEKELREQK 303
Query: 224 EFWENELQIEQENEK--QLKDQLQEIRQKITECENKLKDYLAQIRTMESGLEAEKLQREV 281
+ E E Q++++ EK + +++++E +K+ E +L + Q+R E + ++ +
Sbjct: 304 KLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWE 363
Query: 282 QEAQVNEEEVKGKIGKVKGEIDIQGQQSLRL---ENGIKAVERSLGQATKRLQDKEQEL- 337
Q+ ++ E+E + + + E + + Q+ R+ E ++ E ++ + +++Q +E+ +
Sbjct: 364 QDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMW 423
Query: 338 EQLTKELRQVNLQQ 351
EQ KE +Q L +
Sbjct: 424 EQEEKEWQQQRLPE 437
Score = 52.0 bits (123), Expect = 9e-07
Identities = 45/206 (21%), Positives = 102/206 (49%), Gaps = 10/206 (4%)
Query: 150 EFKQKVLNNCKTTADELKKLIRLQTEKLQSIEKQLESNEIEI-----RFWEQKYNSNLEE 204
E ++K+ + ++ +K+ R Q E+L EKQ+ E ++ R WEQ +E
Sbjct: 314 EQEEKMWEQEEKMREQEEKMWR-QEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKE 372
Query: 205 EIVRLEQKIKRNDVEIEEEE---FWENELQIEQENEKQLKDQLQEIRQKITECENKLKDY 261
E +R ++K+ + +++EEE E +++ E+E ++ ++++Q+ + + E E K
Sbjct: 373 ERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQ 432
Query: 262 LAQIRTMESGLEAEKLQREVQEAQVNEEEVKGKIGKVKGEIDIQGQQSLR-LENGIKAVE 320
E E EK+Q + ++ EE+++ + E + Q+ +R E+ + E
Sbjct: 433 QRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQE 492
Query: 321 RSLGQATKRLQDKEQELEQLTKELRQ 346
+ +++ D+E+ + + + LR+
Sbjct: 493 EKMRDQEQKMWDQEERMWEQDERLRE 518
Score = 50.1 bits (118), Expect = 4e-06
Identities = 40/188 (21%), Positives = 97/188 (51%), Gaps = 14/188 (7%)
Query: 165 ELKKLIRLQTEKLQSIEKQLE---SNEIEIRFWEQKYNSNLEEEIVRLEQKIKRND--VE 219
E ++ +R Q + Q EK E + E E + W+Q+ EE + E+K++ + +
Sbjct: 518 EKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMR 577
Query: 220 IEEEEFWENELQIEQENEK--QLKDQLQEIRQKITECENKLKDYLAQIRTMESGLEAEKL 277
+EE+ E E ++ ++ EK + ++++QE +K+ E E K+ + + + E E++
Sbjct: 578 EQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQ----EEM 633
Query: 278 QREVQEAQVNEEEVKGKIGKVKGEIDIQGQQSLRLENGIKAVERSLGQATKRLQDKEQEL 337
E +E +EE K+ + + ++ Q ++ E ++ E + + +++Q +E+++
Sbjct: 634 MWEQEEKMQEQEE---KMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKM 690
Query: 338 EQLTKELR 345
+ +++R
Sbjct: 691 REQEEKMR 698
Score = 49.7 bits (117), Expect = 5e-06
Identities = 44/205 (21%), Positives = 103/205 (50%), Gaps = 22/205 (10%)
Query: 152 KQKVLNNCKTTADELKKLIRLQTEKLQSIEKQLESNEIEIRFWEQKYNSNLEEEIVR-LE 210
+QK L + E ++ + Q EK++ E+++ E R WEQ+ +E+ +R E
Sbjct: 301 EQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQ--EERLWEQEKQMREQEQKMRDQE 358
Query: 211 QKIKRNDVEI--EEEEFWENELQIEQENEKQLKDQLQEIRQKITECENKLKDYLAQIRTM 268
+++ D + +EE E E EQE + Q +++++E +K+ E E +++ +++
Sbjct: 359 ERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQ 418
Query: 269 ESGL---------------EAEKLQREVQEAQVNEEEVKGKIGKVKGEIDIQGQQ-SLRL 312
E + + EKL E ++ Q EE++ + K++ + ++ GQ+ +
Sbjct: 419 EENMWEQEEKEWQQQRLPEQKEKLW-EQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWR 477
Query: 313 ENGIKAVERSLGQATKRLQDKEQEL 337
+ ++ E + + ++++D+EQ++
Sbjct: 478 QEKMREQEDQMWEQEEKMRDQEQKM 502
Score = 48.5 bits (114), Expect = 1e-05
Identities = 48/260 (18%), Positives = 129/260 (49%), Gaps = 18/260 (6%)
Query: 95 RIPERTLYRQSLPPLAKLRPQIDKSIKRREPKRKSLTFTGGAKGLMDIFGKGKETEFKQK 154
R+PE+ ++ L K++ Q +K ++ E R G K + + + K E + +
Sbjct: 434 RLPEQ---KEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKM---WRQEKMREQEDQ 487
Query: 155 VLNNCKTTADELKKLIRLQTEKLQSIEKQLESNEIEIR----FWEQKYNSNLEEEIVRLE 210
+ + D+ +K+ Q E++ +++L E +R W+Q+ E++ E
Sbjct: 488 MWEQEEKMRDQEQKMWD-QEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQE 546
Query: 211 QKIKRNDVEIEEEEFW---ENELQIEQENEKQLKDQLQEIRQKITECENKLKDYLAQIRT 267
+K + ++ EEE E +++ E+E ++ ++++QE +K+ E E K+ + +++
Sbjct: 547 KKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQE 606
Query: 268 MESGL--EAEKLQREVQEAQVNEEEVKGKIGKVKGEIDIQGQQSLRLENGIKAVERSLGQ 325
E + + EK+ + +E ++ E+E + + + ++ Q ++ E ++ E + +
Sbjct: 607 QEEKMWEQEEKMWEQEEEDKMQEQE--EMMWEQEEKMQEQEEKMWEQEEKMREQEEKMRE 664
Query: 326 ATKRLQDKEQELEQLTKELR 345
+++Q +E+++ + ++++
Sbjct: 665 QEEKMQGQEEKMREQEEKMQ 684
Score = 47.8 bits (112), Expect = 2e-05
Identities = 50/233 (21%), Positives = 115/233 (49%), Gaps = 34/233 (14%)
Query: 147 KETEFKQKVLNNCKTTADELKKLIRLQTEKLQSIEKQLESNEI----EIRFWEQKYNSNL 202
+E E++Q+ L K E +K+ + Q EK+ E+++ E E + W Q+
Sbjct: 426 EEKEWQQQRLPEQKEKLWEQEKM-QEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQ 484
Query: 203 EEEIVRLEQKIKRNDVEI--EEEEFWENELQIEQENE-----KQLKDQLQEIRQ--KITE 253
E+++ E+K++ + ++ +EE WE + ++ ++ E K++ Q +++R+ K E
Sbjct: 485 EDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQE 544
Query: 254 CENKLKDYLAQIRTMESGLEAEKLQREV-------------QEAQVNEEEVK--GKIGKV 298
E K D ++R E E EK RE QE ++ E+E K + K+
Sbjct: 545 QEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKM 604
Query: 299 KGEIDIQGQQSLRL-----ENGIKAVERSLGQATKRLQDKEQELEQLTKELRQ 346
+ + + +Q ++ E+ ++ E + + +++Q++E+++ + +++R+
Sbjct: 605 QEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMRE 657
Score = 47.0 bits (110), Expect = 3e-05
Identities = 39/212 (18%), Positives = 103/212 (48%), Gaps = 29/212 (13%)
Query: 173 QTEKLQSIEKQLESNEIEIRFWEQKYNSNLEEEIVRLEQKIKRNDVEIEEEEFWENELQI 232
+ E+++ EK++ E +R E+K E + E++ ++ + ++E+ WE E
Sbjct: 390 EEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQ 449
Query: 233 EQEN-----EKQLKDQ---------------LQEIRQKITECENKLKDYLAQIRTMESGL 272
EQE E++++DQ ++E ++ E E K++D ++ E +
Sbjct: 450 EQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERM 509
Query: 273 -EAEKLQREVQEAQVNEEEVKGKIGKVKGEIDIQGQ--------QSLRLENGIKAVERSL 323
E ++ RE +E ++++ + K++ E Q Q + +R E ++ E+ +
Sbjct: 510 WEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKM 569
Query: 324 GQATKRLQDKEQELEQLTKELRQVNLQQFIQQ 355
+ + ++++E+++++ +++R+ + + Q+
Sbjct: 570 REEEEMMREQEEKMQEQEEKMREQEEKMWEQE 601
>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
Length = 1411
Score = 62.0 bits (149), Expect = 9e-10
Identities = 66/325 (20%), Positives = 146/325 (44%), Gaps = 51/325 (15%)
Query: 68 QYASDVQLILRRTGPSLSERPTSDSVARIPERTLYRQSLPPLAKLRPQIDKSIKRREPKR 127
Q +D+QL L R L E+ T+ + +L+ Q+DK+ K++ ++
Sbjct: 453 QQVADLQLKLSRLEEQLKEKVTNST------------------ELQHQLDKT-KQQHQEQ 493
Query: 128 KSLTFTGGAK---GLMDIFGKGKETEFKQKVLNNCKTTADELKKLIRLQTEKLQSIEKQL 184
++L + AK D+ ++ K + + N + + K+ I L ++ + + ++
Sbjct: 494 QALQQSTTAKLREAQNDLEQVLRQIGDKDQKIQNLEALLQKSKENISLLEKEREDLYAKI 553
Query: 185 ESNEIEIRFWEQ--KYNSNLEEEIVRLEQKIKRNDVEIEEEEFWENELQIEQENEKQLKD 242
++ E E Q + N L+E++ +L +K+K N+ + ++ ++ L D
Sbjct: 554 QAGEGETAVLNQLQEKNHTLQEQVTQLTEKLK-------------NQSESHKQAQENLHD 600
Query: 243 QLQEIRQKITECENKLKDYLAQIRTMESGLEAEK---LQREVQEAQVNEEEVKGKIGKVK 299
Q+QE + + ++++ + + S L K Q ++Q E + + K
Sbjct: 601 QVQEQKAHLRAAQDRVLSLETSVNELNSQLNESKEKVSQLDIQIKAKTELLLSAEAAKTA 660
Query: 300 GEIDIQ-----GQQSLR-LENGIKAVERSLGQATKRLQDKEQELEQLTKELRQ-----VN 348
D+Q Q +L+ + + + L Q T +LQDK++ QL L++ ++
Sbjct: 661 QRADLQNHLDTAQNALQDKQQELNKITTQLDQVTAKLQDKQEHCSQLESHLKEYKEKYLS 720
Query: 349 LQQFIQQTGTKVTVLPAEPIEIEAS 373
L+Q ++ ++ L A+ +E++AS
Sbjct: 721 LEQKTEELEGQIKKLEADSLEVKAS 745
Score = 60.1 bits (144), Expect = 3e-09
Identities = 58/249 (23%), Positives = 124/249 (49%), Gaps = 29/249 (11%)
Query: 109 LAKLRPQIDKSIKRREPKRKSLTFTGGAKGLM--DIFGKGKETEFKQKVLNN-CKTTADE 165
++ R + K + E ++ LT K ++ D +ET+ + + LNN +TT E
Sbjct: 781 VSSTRLDLQKKSEALESIKQKLTKQEEEKQILKQDFETLSQETKIQHEELNNRIQTTVTE 840
Query: 166 LKK--------LIRLQT--EKLQSIEKQLESNEIEIRFWEQKYNS---NLEEEIVRLEQK 212
L+K + L T +KL + L++++ E QK + +LE+ L+ +
Sbjct: 841 LQKVKMEKEALMTELSTVKDKLSKVSDSLKNSKSEFEKENQKGKAAILDLEKTCKELKHQ 900
Query: 213 IK-RNDVEIEEEEFWENELQIEQENEKQLKDQLQEIRQKITECENKLKDYLAQIRTMESG 271
++ + + ++E++ + L+ E+E QLK +L +++++ + +N LK ++
Sbjct: 901 LQVQMENTLKEQKELKKSLEKEKEASHQLKLELNSMQEQLIQAQNTLK---------QNE 951
Query: 272 LEAEKLQREVQEAQVNEEEVKGKIGKVKGEIDIQGQQSLRLENGIKAVERSLGQATKRLQ 331
E ++LQ + E + + E+ K +I ++GE+ I Q LEN +++ L QA + L
Sbjct: 952 KEEQQLQGNINELKQSSEQKKKQIEALQGELKIAVLQKTELEN---KLQQQLTQAAQELA 1008
Query: 332 DKEQELEQL 340
+++++ L
Sbjct: 1009 AEKEKISVL 1017
Score = 50.1 bits (118), Expect = 4e-06
Identities = 54/251 (21%), Positives = 113/251 (45%), Gaps = 40/251 (15%)
Query: 139 LMDIFGKGKETEFKQKVLNNCK----------TTADELKKLIRLQTEKLQSIEKQLESNE 188
LMD +E E +K+ + CK T +L+ + +++ ++L+ +
Sbjct: 236 LMDNMTLERERE-SEKLKDECKKLQSQYASSEATISQLRSELAKGPQEVAVYVQELQKLK 294
Query: 189 IEIRFWEQKYNSNLEEEIVRLEQKIKRNDVEIEEEEFWENELQIEQENEKQLKDQLQEIR 248
+ QK N L E +++ EQ + + + EE + +Q ++K L Q+++
Sbjct: 295 SSVNELTQK-NQTLTENLLKKEQDYTKLEEKHNEESVSKKNIQATL-HQKDL--DCQQLQ 350
Query: 249 QKITECENKLKDYLAQIRTMESGLEAEKLQREVQEAQVNEEEVKGKIGKVKGEIDIQGQQ 308
+++ E L + + E G +KL+ E+ E + + +K + +++ + + + Q
Sbjct: 351 SRLSASETSL--HRIHVELSEKGEATQKLKEELSEVETKYQHLKAEFKQLQQQREEKEQH 408
Query: 309 SLRLENGIKAV-------ERSLGQA-----------TKRLQDKEQELEQLTKELRQVNLQ 350
L+L++ I + ER LG+A +++L DKEQ++ L Q+ L
Sbjct: 409 GLQLQSEINQLHSKLLETERQLGEAHGRLKEQRQLSSEKLMDKEQQVADL-----QLKLS 463
Query: 351 QFIQQTGTKVT 361
+ +Q KVT
Sbjct: 464 RLEEQLKEKVT 474
Score = 50.1 bits (118), Expect = 4e-06
Identities = 50/229 (21%), Positives = 111/229 (48%), Gaps = 16/229 (6%)
Query: 152 KQKVLN-NCKTTADELKKLIRLQTEKLQSIEKQLESNEIEIRFWEQKYNSNLEE-EIVRL 209
+Q+ LN + + A EL K + ++ E + S L+ + +QK EE +I++
Sbjct: 755 QQRQLNTDLELRATELSKQLEMEKEIVSSTRLDLQKKSEALESIKQKLTKQEEEKQILKQ 814
Query: 210 EQKIKRNDVEIEEEEFWEN------ELQIEQENEKQLKDQLQEIRQKITECENKLKDYLA 263
+ + + +I+ EE ELQ + ++ L +L ++ K+++ + LK+ +
Sbjct: 815 DFETLSQETKIQHEELNNRIQTTVTELQKVKMEKEALMTELSTVKDKLSKVSDSLKNSKS 874
Query: 264 QI-RTMESG----LEAEKLQREVQ-EAQVNEEEVKGKIGKVKGEIDIQGQQSLRLENGIK 317
+ + + G L+ EK +E++ + QV E + ++K ++ + + S +L+ +
Sbjct: 875 EFEKENQKGKAAILDLEKTCKELKHQLQVQMENTLKEQKELKKSLEKEKEASHQLKLELN 934
Query: 318 AVERSLGQATKRLQDKEQELEQLTKELRQVNLQQFIQQTGTKVTVLPAE 366
+++ L QA L+ E+E +QL + + L+Q +Q ++ L E
Sbjct: 935 SMQEQLIQAQNTLKQNEKEEQQLQGNINE--LKQSSEQKKKQIEALQGE 981
Score = 48.5 bits (114), Expect = 1e-05
Identities = 53/229 (23%), Positives = 111/229 (48%), Gaps = 20/229 (8%)
Query: 156 LNNCKTTADELKKLIRLQTEKLQSIEKQLESNEIEIRFWEQKYNSNLEEEIVRLEQKIKR 215
LN K +L I+ +TE L S E + ++ Q + + + +Q++ +
Sbjct: 630 LNESKEKVSQLDIQIKAKTELLLSAEAAKTAQRADL----QNHLDTAQNALQDKQQELNK 685
Query: 216 NDVEIEEEEFWENELQIEQENEKQLKDQLQEIRQKITECENKLKDYLAQIRTMES----- 270
++++ +LQ +QE+ QL+ L+E ++K E K ++ QI+ +E+
Sbjct: 686 ITTQLDQVTA---KLQDKQEHCSQLESHLKEYKEKYLSLEQKTEELEGQIKKLEADSLEV 742
Query: 271 -GLEAEKLQREVQEAQVNEE-EVKG-KIGK-VKGEIDIQGQQSLRLENGIKAVERSLGQA 326
+ + LQ Q+ Q+N + E++ ++ K ++ E +I L L+ +A+E +
Sbjct: 743 KASKEQALQDLQQQRQLNTDLELRATELSKQLEMEKEIVSSTRLDLQKKSEALESIKQKL 802
Query: 327 TKRLQDKE---QELEQLTKELRQVNLQQFIQQTGTKVTVLPAEPIEIEA 372
TK+ ++K+ Q+ E L++E + + ++ + T VT L +E EA
Sbjct: 803 TKQEEEKQILKQDFETLSQETK-IQHEELNNRIQTTVTELQKVKMEKEA 850
Score = 46.2 bits (108), Expect = 5e-05
Identities = 50/255 (19%), Positives = 111/255 (43%), Gaps = 45/255 (17%)
Query: 169 LIRLQTEKLQSIEKQLESNEIEIRFWEQKYNSNLEEEIVRLEQKIKRNDVEIEE-EEFWE 227
L+ + +LQS+E+QLE + E N N+++ EQK + EI + + ++
Sbjct: 129 LVTDSSAELQSLEQQLEEAQTE--------NFNIKQMKDLFEQKAAQLATEIADIKSKYD 180
Query: 228 NELQIEQENEKQLKDQLQEIRQKITECEN---------------KLKDYLAQIRTMESGL 272
E + + E+++ +E+ ++ T ++ LK L Q++T+ +
Sbjct: 181 EERSLREAAEQKVTRLTEELNKEATVIQDLKTELLQRPGIEDVAVLKKELVQVQTLMDNM 240
Query: 273 -------------EAEKLQREVQEAQVNEEEVKGKIGKVKGEIDIQGQQSLRLENGIKAV 319
E +KLQ + ++ +++ ++ K E+ + Q+ +L++ + +
Sbjct: 241 TLERERESEKLKDECKKLQSQYASSEATISQLRSELAKGPQEVAVYVQELQKLKSSVNEL 300
Query: 320 ERSLGQATKRLQDKEQELEQLTKE-----LRQVNLQQFIQQTGTKVTVLPAEPIEIEASH 374
+ T+ L KEQ+ +L ++ + + N+Q + Q L + + AS
Sbjct: 301 TQKNQTLTENLLKKEQDYTKLEEKHNEESVSKKNIQATLHQKDLDCQQLQS---RLSASE 357
Query: 375 ADIERGIIILSDKQE 389
+ R + LS+K E
Sbjct: 358 TSLHRIHVELSEKGE 372
Score = 43.1 bits (100), Expect = 4e-04
Identities = 66/283 (23%), Positives = 124/283 (43%), Gaps = 51/283 (18%)
Query: 118 KSIKRREPKRKSLTFTGGAKGLMDIFGKGKETEFKQKVLNNCKTTADELKKLI------- 170
K+ ++ +K K L DI KE K+K L N K+ E++++
Sbjct: 1084 KATLEQDSAKKEQQLQERCKALQDI---QKEKSLKEKELVNEKSKLAEIEEIKCRQEKEI 1140
Query: 171 -----RLQTEKLQSI---------EKQLESNEIEIRFWEQKYNSNLEEEIVRLEQKIKRN 216
L++ KL+SI ++ L ++E++ + +E+E + Q+I ++
Sbjct: 1141 TKLNEELKSHKLESIKEITNLKDAKQLLIQQKLELQGKADSLKAAVEQE--KRNQQILKD 1198
Query: 217 DVEIEEEEFWENELQIEQENEKQLKDQLQEIRQKITECENKLKDYLAQIRTMESGL---- 272
V+ EEEE + ++ E + ++K+ +E+ K E EN+ K QI + L
Sbjct: 1199 QVKKEEEELKKEFIEKEAKLHSEIKE--KEVGMKKHE-ENEAK-LTMQITALNENLGTVK 1254
Query: 273 -EAEKLQREVQEAQVNEEEVKGKIGKVKGEIDIQGQQSLRLENGIKAVERSLGQATKRLQ 331
E + QR V E + ++++G+I + E +Q Q R R+L +R
Sbjct: 1255 KEWQSSQRRVSELEKQTDDLRGEIAVL--EATVQNNQDER---------RAL---LERCL 1300
Query: 332 DKEQELEQLTKELRQVNLQQFIQQTGTKVTVLPAEPIEIEASH 374
E E+E+L + + + LQ+ + T V L E ++ H
Sbjct: 1301 KGEGEIEKL--QTKVLELQRKLDNTTAAVQELGRENQSLQIKH 1341
Score = 42.7 bits (99), Expect = 6e-04
Identities = 44/251 (17%), Positives = 105/251 (41%), Gaps = 48/251 (19%)
Query: 140 MDIFGKGKETEFKQKVLNNCKTTADELKKLIRLQTEKLQSIEKQLESNEIEIRFWEQKYN 199
+++ KG+ T+ ++ L+ +T LK + + +++Q E E ++
Sbjct: 365 VELSEKGEATQKLKEELSEVETKYQHLKA-------EFKQLQQQREEKE--------QHG 409
Query: 200 SNLEEEIVRLEQKIKRNDVEIEEEEF-WENELQIEQENEKQLKDQLQEIRQKITECENKL 258
L+ EI +L K+ + ++ E + + Q+ E + Q+ +++ K++ E +L
Sbjct: 410 LQLQSEINQLHSKLLETERQLGEAHGRLKEQRQLSSEKLMDKEQQVADLQLKLSRLEEQL 469
Query: 259 KDYLAQIRTMESGLEAEKLQREVQEAQVNEEEVKGKIGKVKGEIDIQGQQSLRLENGIKA 318
K+ + ++ L+ K Q + Q+A K ++
Sbjct: 470 KEKVTNSTELQHQLDKTKQQHQEQQALQQSTTAK-----------------------LRE 506
Query: 319 VERSLGQATKRLQDKEQELEQLTKELRQVNLQQFIQQTGTKVTVLPAEPIEIEASHADIE 378
+ L Q +++ DK+Q+++ NL+ +Q++ +++L E ++ A E
Sbjct: 507 AQNDLEQVLRQIGDKDQKIQ---------NLEALLQKSKENISLLEKEREDLYAKIQAGE 557
Query: 379 RGIIILSDKQE 389
+L+ QE
Sbjct: 558 GETAVLNQLQE 568
Score = 42.7 bits (99), Expect = 6e-04
Identities = 56/244 (22%), Positives = 103/244 (42%), Gaps = 48/244 (19%)
Query: 147 KETEFKQKVLNNCKTTADELKKLIRLQTEKLQSIEKQLESN---EIEIRFWEQKYNSNLE 203
KE + + + + + T ELK +++Q E +K+L+ + E E + ++++
Sbjct: 878 KENQKGKAAILDLEKTCKELKHQLQVQMENTLKEQKELKKSLEKEKEASHQLKLELNSMQ 937
Query: 204 EEIVRLEQKIKRNDVEIEEEEFWENELQIEQENEKQLKDQLQ-----EIRQKITECENKL 258
E++++ + +K+N+ E ++ + NEL+ E +K+ + LQ + QK TE ENKL
Sbjct: 938 EQLIQAQNTLKQNEKEEQQLQGNINELKQSSEQKKKQIEALQGELKIAVLQK-TELENKL 996
Query: 259 KDYLAQIRTMESGLEAEK---LQREVQEAQVNEEEVKGKIGKVKGEI------------- 302
+ L Q E E EK LQ +++Q ++++ + E+
Sbjct: 997 QQQLTQA-AQELAAEKEKISVLQNNYEKSQETFKQLQSDFYGRESELLATRQDLKSVEEK 1055
Query: 303 -------------DIQGQQSL---------RLENGIKAVERSLGQATKRLQDKEQELEQL 340
I Q L LE E+ L + K LQD ++E
Sbjct: 1056 LSLAQEDLISNRNQIGNQNKLIQELKTAKATLEQDSAKKEQQLQERCKALQDIQKEKSLK 1115
Query: 341 TKEL 344
KEL
Sbjct: 1116 EKEL 1119
Score = 39.3 bits (90), Expect = 0.006
Identities = 42/197 (21%), Positives = 90/197 (45%), Gaps = 32/197 (16%)
Query: 204 EEIVRLEQKIKRNDVEIEEEEFWENELQIEQENEKQLKDQLQEIRQKITECENKLKDYLA 263
+++ L Q+++ ++EE+++ EL+ E E + L+ Q + +T+
Sbjct: 83 DDVTLLRQEVQDLQASLKEEKWYSEELKKELEKYQGLQQQEAKPDGLVTD---------- 132
Query: 264 QIRTMESGLEAEKLQREVQEAQVNEEEVKGKIGKVKGEIDIQGQQSLRLENGIKAVERSL 323
S E + L+++++EAQ +K ++K D+ Q++ +L I ++
Sbjct: 133 ------SSAELQSLEQQLEEAQTENFNIK----QMK---DLFEQKAAQLATEIADIKSKY 179
Query: 324 GQATKRLQDKEQELEQLTKELR------QVNLQQFIQQTGTK-VTVLPAEPIEIEA--SH 374
+ + EQ++ +LT+EL Q + +Q+ G + V VL E ++++ +
Sbjct: 180 DEERSLREAAEQKVTRLTEELNKEATVIQDLKTELLQRPGIEDVAVLKKELVQVQTLMDN 239
Query: 375 ADIERGIIILSDKQECK 391
+ER K ECK
Sbjct: 240 MTLERERESEKLKDECK 256
Score = 37.4 bits (85), Expect = 0.024
Identities = 43/198 (21%), Positives = 94/198 (47%), Gaps = 20/198 (10%)
Query: 175 EKLQSIEKQLESNEIEIRFWEQKYN------SNLEEEIVRLEQKIKRNDVEIEEEEFWEN 228
EKL ++ L SN +I + + LE++ + EQ+++ +++ + ++
Sbjct: 1054 EKLSLAQEDLISNRNQIGNQNKLIQELKTAKATLEQDSAKKEQQLQERCKALQDIQKEKS 1113
Query: 229 ELQIEQENEKQLKDQLQEIR----QKITECENKLKDYLAQIRTMESGLEAEKLQREVQEA 284
+ E NEK +++EI+ ++IT+ +LK + +ES E L+ Q
Sbjct: 1114 LKEKELVNEKSKLAEIEEIKCRQEKEITKLNEELKSH-----KLESIKEITNLKDAKQLL 1168
Query: 285 QVNEEEVKGKIGKVKGEIDIQGQQSLRLENGIKAVERSLGQATKRLQDKEQELEQLTKEL 344
+ E++GK +K ++ + + L++ +K E L K +KE +L KE
Sbjct: 1169 IQQKLELQGKADSLKAAVEQEKRNQQILKDQVKKEEEEL---KKEFIEKEAKLHSEIKE- 1224
Query: 345 RQVNLQQFIQQTGTKVTV 362
++V +++ ++ K+T+
Sbjct: 1225 KEVGMKKH-EENEAKLTM 1241
Score = 29.6 bits (65), Expect = 4.9
Identities = 38/151 (25%), Positives = 65/151 (43%), Gaps = 16/151 (10%)
Query: 120 IKRREPKRKSLTFTGGAKGLMDIFGKGKETEFKQKVLNNCKTTAD---------ELKKLI 170
+K+ E + K AK +I K KE K+ N K T +KK
Sbjct: 1200 VKKEEEELKKEFIEKEAKLHSEI--KEKEVGMKKHEENEAKLTMQITALNENLGTVKKEW 1257
Query: 171 RLQTEKLQSIEKQLESNEIEIRFWEQKYNSNLEEEIVRLEQKIKRNDVEIEEEEFWENEL 230
+ ++ +EKQ + EI E +N +E LE+ +K + EIE+ + EL
Sbjct: 1258 QSSQRRVSELEKQTDDLRGEIAVLEATVQNNQDERRALLERCLK-GEGEIEKLQTKVLEL 1316
Query: 231 QIEQENE----KQLKDQLQEIRQKITECENK 257
Q + +N ++L + Q ++ K T+ N+
Sbjct: 1317 QRKLDNTTAAVQELGRENQSLQIKHTQALNR 1347
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 61.6 bits (148), Expect = 1e-09
Identities = 49/177 (27%), Positives = 94/177 (53%), Gaps = 9/177 (5%)
Query: 170 IRLQTEKLQSIEKQLESNEIEIRFWEQKYNSNLEEEIVRLEQKIKRNDVEIEEEEFW--- 226
IR Q EK+ E+++ E +IR E+K EE+I E+KI+ + +I E+E
Sbjct: 490 IRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQ-EEKIREQEEKIREQEEKIREQEEMMQE 548
Query: 227 ENELQIEQENEKQLKDQLQEIRQKITECENKLKDYLAQIRTMESGL--EAEKLQREVQEA 284
+ E EQE + Q +++++ +KI E E K+++ +IR E + + EK++ + +
Sbjct: 549 QEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMM 608
Query: 285 QVNEE---EVKGKIGKVKGEIDIQGQQSLRLENGIKAVERSLGQATKRLQDKEQELE 338
Q EE E + K+ + + ++ Q ++ R E + E L Q +++Q+ ++ LE
Sbjct: 609 QEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLE 665
Score = 58.5 bits (140), Expect = 1e-08
Identities = 52/193 (26%), Positives = 98/193 (50%), Gaps = 18/193 (9%)
Query: 173 QTEKLQSIEKQLESNEIEIRFWEQKYNSNLEEEIVRLEQKI--KRNDVEIEEEEFWENEL 230
Q EK+Q E++++ E +IR E+K EE++ R E+ + K + +EE WE E
Sbjct: 305 QEEKIQEWEEKIQEQEEKIREQEEKIREQ-EEKMRRQEEMMWEKEEKMRRQEEMMWEKE- 362
Query: 231 QIEQENEKQLKDQLQEIRQKITECENKLKDYLAQIRTMESGLEAEKLQREVQEAQVNEEE 290
E ++L++ + E +KI E E K+ + +IR E + E+ RE ++ Q E +
Sbjct: 363 ----EKMRRLEEMMWEKEEKIRELEEKMHEQ-EKIREQEEKRQEEEKIREQEKRQEQEAK 417
Query: 291 V---KGKIGKVKGEIDIQGQQSLRLENGIKAVERSLGQATKRLQDKEQELEQLTKELRQV 347
+ + KI + + +I Q ++ R E I E+ R ++K QE E++ ++ ++
Sbjct: 418 MWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKI------REEEKRQEQEEMWRQEEKI 471
Query: 348 NLQQFIQQTGTKV 360
Q+ I + K+
Sbjct: 472 REQEEIWRQKEKM 484
Score = 57.4 bits (137), Expect = 2e-08
Identities = 41/204 (20%), Positives = 104/204 (50%), Gaps = 6/204 (2%)
Query: 148 ETEFKQKVLNNCKTTADELKKLIRLQTEKLQSIEKQLESNEIEIRFWEQKYNSNLEEEIV 207
E E K + L +E + + + + + I +Q E + E + EQ+ E ++
Sbjct: 360 EKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMW 419
Query: 208 RLEQKIKRNDVEIEEEE--FWENELQIEQENEKQLKDQLQEIRQKITECENKLKDYLAQI 265
R E+KI+ + +I E+E W E +I E EK +++ ++ ++++ E K+++
Sbjct: 420 RQEEKIREQEEKIREQEKKMWRQEEKI-HEQEKIREEEKRQEQEEMWRQEEKIREQEEIW 478
Query: 266 RTMESGLEAEKLQREVQEAQVNEEEVKGKIGKVKGEIDIQGQQSLRL---ENGIKAVERS 322
R E E EK++++ ++ EE++ + K++ + + +Q ++ E I+ E
Sbjct: 479 RQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEK 538
Query: 323 LGQATKRLQDKEQELEQLTKELRQ 346
+ + + +Q++E+++ + +++++
Sbjct: 539 IREQEEMMQEQEEKMGEQEEKMQE 562
Score = 57.0 bits (136), Expect = 3e-08
Identities = 52/231 (22%), Positives = 109/231 (47%), Gaps = 38/231 (16%)
Query: 152 KQKVLNNCKTTADELKKLIRLQTEKLQSIEK---QLESNEIEIRFWEQKYNSNLEEEIVR 208
K++ + + E +K IR Q EK Q EK Q + E E + W Q+ +EE +R
Sbjct: 375 KEEKIRELEEKMHEQEK-IREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIR 433
Query: 209 LEQK--------------IKRNDVEIEEEEFWENELQIEQENE----KQLKDQLQEIR-- 248
++K I+ + E+EE W E +I ++ E K+ + ++IR
Sbjct: 434 EQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQ 493
Query: 249 -QKITECENKLKDYLAQIRTMESGLEAEKLQREVQEAQVNEEEVK------------GKI 295
+K+ E K+ D +IR E + ++ + QE ++ E+E K K+
Sbjct: 494 EEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKM 553
Query: 296 GKVKGEIDIQGQQSLRLENGIKAVERSLGQATKRLQDKEQELEQLTKELRQ 346
G+ + ++ Q ++ R E I+ E + + ++++++E+++ + +++R+
Sbjct: 554 GEQEEKMQEQ-EKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIRE 603
Score = 55.8 bits (133), Expect = 6e-08
Identities = 43/207 (20%), Positives = 110/207 (53%), Gaps = 31/207 (14%)
Query: 173 QTEKLQSIEKQLESNEI---------EIRFWEQKYNSNLEEEIVRLEQKIKRNDVEI--- 220
+ EK++ EK+ E E+ + W QK + +E+I + E+K+ R + ++
Sbjct: 448 EQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQ 507
Query: 221 ------EEEEFWENELQIEQENEKQLKDQLQEIRQK---ITECENKLKDYLAQIRTMESG 271
+EE+ W E +I ++ EK +++Q ++IR++ + E E K+ + +++
Sbjct: 508 EEKIREQEEKMWRQEEKIREQEEK-IREQEEKIREQEEMMQEQEEKMGEQEEKMQ----- 561
Query: 272 LEAEKLQREVQEAQVNEEEV---KGKIGKVKGEIDIQGQQSLRLENGIKAVERSLGQATK 328
E EK++R+ ++ + EE++ K KI + + +I Q ++ E ++ E + + +
Sbjct: 562 -EQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEE 620
Query: 329 RLQDKEQELEQLTKELRQVNLQQFIQQ 355
++ ++E+++++ +++R+ + + Q+
Sbjct: 621 KMCEQEEKMQEQEEKMRRQEEKMWEQE 647
Score = 52.4 bits (124), Expect = 7e-07
Identities = 52/199 (26%), Positives = 106/199 (53%), Gaps = 22/199 (11%)
Query: 165 ELKKLIRLQTEKLQSIEKQLESNEIEIRFWEQKYNSNLEEEIV-RLEQKIKRNDVEIEEE 223
E ++ IR Q EK++ E+++ E WE++ +EE++ E+K++R EE
Sbjct: 318 EQEEKIREQEEKIREQEEKMRRQ--EEMMWEKEEKMRRQEEMMWEKEEKMRR-----LEE 370
Query: 224 EFWENELQIEQENEKQLKDQLQEIRQKITECENKLKDYLAQIRTMESGLEAE-KLQREVQ 282
WE E E ++L++++ E ++KI E E K ++ +IR E E E K+ R+ +
Sbjct: 371 MMWEKE-----EKIRELEEKMHE-QEKIREQEEKRQEE-EKIREQEKRQEQEAKMWRQEE 423
Query: 283 EAQVNEEEVKGKIGKV-KGEIDIQGQQSLRLENGIKAVERSLGQATKRLQDKEQELEQLT 341
+ + EE+++ + K+ + E I Q+ +R E +R + R ++K +E E++
Sbjct: 424 KIREQEEKIREQEKKMWRQEEKIHEQEKIREEE-----KRQEQEEMWRQEEKIREQEEIW 478
Query: 342 KELRQVNLQQFIQQTGTKV 360
++ +++ Q+ I++ KV
Sbjct: 479 RQKEKMHEQEKIRKQEEKV 497
Score = 51.6 bits (122), Expect = 1e-06
Identities = 53/260 (20%), Positives = 121/260 (46%), Gaps = 23/260 (8%)
Query: 104 QSLPPLAKLRPQIDKSIKRREPKRKSLTFTGGAKGLMDIFGKGKETEFKQKVLNNCKTTA 163
Q+L +A + + D+ I+ +R +L+ + D K K + ++K L ++
Sbjct: 179 QALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEK-LQLVESEK 237
Query: 164 DELKKLIRLQTEKLQSIEKQLESNEIEIRFWEQKYNSNLEEEIVRLEQKIKRNDVEIEEE 223
E++ ++ KL+ + L ++ Q +L +E+ + K++ ++EE
Sbjct: 238 SEIQLNVKELKRKLERAKLLLPQQQL------QAEADHLGKELQSVSAKLQ---AQVEEN 288
Query: 224 EFWENELQIEQENEKQLKDQLQEIRQKITECENKLKDYLAQIRTMESGL-EAEKLQREVQ 282
E W Q ++E + ++++QE +KI E E K+++ +IR E + E++ E +
Sbjct: 289 ELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKE 348
Query: 283 EAQVNEEEVKGKIGKVKGEIDIQGQQSLRLENGIKAVERSLGQATKRL--QDKEQELEQL 340
E +EE+ + + ++ RLE + E + + +++ Q+K +E E+
Sbjct: 349 EKMRRQEEMMWE----------KEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEK 398
Query: 341 TKELRQVNLQQFIQQTGTKV 360
+E ++ Q+ Q+ K+
Sbjct: 399 RQEEEKIREQEKRQEQEAKM 418
Score = 42.4 bits (98), Expect = 7e-04
Identities = 36/138 (26%), Positives = 68/138 (49%), Gaps = 12/138 (8%)
Query: 111 KLRPQIDKSIKRREPKRKSLTFTGGAKGLMDIFGKGKETEFK----QKVLNNCKTTADEL 166
K+R Q +K ++ E ++ G + M K + E K ++ + K E
Sbjct: 531 KIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQ 590
Query: 167 KKLIRLQTEKLQSIEKQLESNEIEIRFWEQKYN-SNLEEEIVRLEQKIKRNDVEIEEEEF 225
++ I Q EK++ E+ ++ E E + WEQ+ EE++ E+K++R +EE+
Sbjct: 591 EEKIWEQEEKIREQEEMMQ--EQEEKMWEQEEKMCEQEEKMQEQEEKMRR-----QEEKM 643
Query: 226 WENELQIEQENEKQLKDQ 243
WE E+++ Q+ EK + Q
Sbjct: 644 WEQEVRLRQQEEKMQEHQ 661
Score = 37.7 bits (86), Expect = 0.018
Identities = 27/154 (17%), Positives = 72/154 (46%), Gaps = 4/154 (2%)
Query: 197 KYNSNLEEEIVRLEQKIKRNDVEIEEEEFWENELQIEQENEKQLKDQLQEIRQKITE--- 253
K+ LE+ + + + K+ D IEE + L +E ++L+E K+ E
Sbjct: 172 KFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQ 231
Query: 254 -CENKLKDYLAQIRTMESGLEAEKLQREVQEAQVNEEEVKGKIGKVKGEIDIQGQQSLRL 312
E++ + ++ ++ LE KL Q+ Q + + ++ V ++ Q +++
Sbjct: 232 LVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELW 291
Query: 313 ENGIKAVERSLGQATKRLQDKEQELEQLTKELRQ 346
+ E + + +++Q+ E+++++ +++R+
Sbjct: 292 NRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIRE 325
>gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens]
Length = 1684
Score = 60.1 bits (144), Expect = 3e-09
Identities = 63/230 (27%), Positives = 107/230 (46%), Gaps = 39/230 (16%)
Query: 159 CKTTADELKKLIRLQTEKLQSIEKQLESNEIEIRFWEQKYNSNLEEEIVRLEQKIKRNDV 218
C+T + + L+ + E LQS K LE +E++ + + LE E ++ EQKIK +
Sbjct: 1061 CETINSDNEDLLA-RIETLQSNAKLLEVQILEVQRAKAMVDKELEAEKLQKEQKIKEHAT 1119
Query: 219 EIEEEEFWENELQIE-QENEKQLKDQLQEIR------QKITECENKLKDYLAQIRTMESG 271
+ E E ELQ++ Q+ +KQL+ +QE+ Q+ T ++ DY
Sbjct: 1120 TVNELE----ELQVQLQKEKKQLQKTMQELELVKKDAQQTTLMNMEIADY---------- 1165
Query: 272 LEAEKLQREVQEAQVNEEEVKGKIGKVKGEIDIQGQQSLRLENGIKAVERSLGQATKRLQ 331
E+L +E+ + N+ KI ++ EI IQ Q+ L+ I +++ S+ Q ++
Sbjct: 1166 ---ERLMKELNQKLTNK---NNKIEDLEQEIKIQKQKQETLQEEITSLQSSVQQYEEKNT 1219
Query: 332 DKEQELEQLTKEL---RQVNLQQFIQQTGTKVTVLPAEPIEIEASHADIE 378
+Q L + KEL +Q I Q K E+EAS +E
Sbjct: 1220 KIKQLLVKTKKELADSKQAETDHLILQASLKG--------ELEASQQQVE 1261
Score = 50.8 bits (120), Expect = 2e-06
Identities = 38/195 (19%), Positives = 98/195 (50%), Gaps = 10/195 (5%)
Query: 164 DELKKLIRLQTEKLQSIEKQLESNEIEIRFWEQK---YNSNLEEEIVRLEQKIKRNDVEI 220
++ K L+R + E++QS ++ L+S+ +E++ +K N NL ++ + Q ++++
Sbjct: 837 EQEKVLLRKELEEIQSEKEALQSDLLEMKNANEKTRLENQNLLIQVEEVSQTCSKSEIHN 896
Query: 221 EEEEFWENELQ-----IEQENEKQLKDQLQEIRQKITECENKLKDYLAQIRTMESGLEAE 275
E+E+ + E + +EQ+ + + +L ++ + + + D L+ ++ +E + E
Sbjct: 897 EKEKCFIKEHENLKPLLEQKELRDRRAELILLKDSLAKSPSVKNDPLSSVKELEE--KIE 954
Query: 276 KLQREVQEAQVNEEEVKGKIGKVKGEIDIQGQQSLRLENGIKAVERSLGQATKRLQDKEQ 335
L++E +E + ++K K K E+D +++ ++ ++++ Q + ++D Q
Sbjct: 955 NLEKECKEKEEKINKIKLVAVKAKKELDSSRKETQTVKEELESLRSEKDQLSASMRDLIQ 1014
Query: 336 ELEQLTKELRQVNLQ 350
E L + Q
Sbjct: 1015 GAESYKNLLLEYEKQ 1029
Score = 45.8 bits (107), Expect = 7e-05
Identities = 52/249 (20%), Positives = 113/249 (45%), Gaps = 35/249 (14%)
Query: 136 AKGLMDIFGKGKETEFKQKVLNNCKTTADELKKL-IRLQTEKLQSIEKQLESNEI----- 189
AK ++D + ++ + +QK+ + TT +EL++L ++LQ EK Q ++K ++ E+
Sbjct: 1095 AKAMVDKELEAEKLQKEQKIKEHA-TTVNELEELQVQLQKEKKQ-LQKTMQELELVKKDA 1152
Query: 190 --------EIRFWEQKY--------NSNLEEEIVRLEQKIKRNDVEIEEEEFWENELQIE 233
EI +E+ N N + E + E KI++ E +EE + ++
Sbjct: 1153 QQTTLMNMEIADYERLMKELNQKLTNKNNKIEDLEQEIKIQKQKQETLQEEITSLQSSVQ 1212
Query: 234 QENEK--QLKDQLQEIRQKITECENKLKDYLAQIRTMESGLEAEKLQREVQEAQVNE--- 288
Q EK ++K L + ++++ + + D+L +++ LEA + Q EV + Q+ E
Sbjct: 1213 QYEEKNTKIKQLLVKTKKELADSKQAETDHLILQASLKGELEASQQQVEVYKIQLAEITS 1272
Query: 289 ------EEVKGKIGKVKGEIDIQGQQSLRLENGIKAVERSLGQATKRLQDKEQELEQLTK 342
E +K + + + Q+ L+ +A + T + + + + K
Sbjct: 1273 EKHKIHEHLKTSAEQHQRTLSAYQQRVTALQEECRAAKAEQATVTSEFESYKVRVHNVLK 1332
Query: 343 ELRQVNLQQ 351
+ + ++ Q
Sbjct: 1333 QQKNKSMSQ 1341
Score = 39.7 bits (91), Expect = 0.005
Identities = 52/231 (22%), Positives = 100/231 (43%), Gaps = 35/231 (15%)
Query: 164 DELKKLIRLQTEKLQSI---EKQLESNEIEIRFWEQKYNSNLEEEIVRLEQKIKRNDVEI 220
D L K ++ + L S+ E+++E+ E E + E+K N + ++V ++ K K D
Sbjct: 930 DSLAKSPSVKNDPLSSVKELEEKIENLEKECKEKEEKIN---KIKLVAVKAK-KELDSSR 985
Query: 221 EEEEFWENELQIEQENEKQLKDQLQEIRQKITECENKLKDYLAQIRTMESGLEAEK---- 276
+E + + EL E+ + KDQL + + + K+ L + L+ EK
Sbjct: 986 KETQTVKEEL----ESLRSEKDQLSASMRDLIQGAESYKNLLLEYEKQSEQLDVEKERAN 1041
Query: 277 --------LQREVQEAQVNEEEVKGKIGKVKGEIDIQGQQSLRLENGIKAVERSLGQATK 328
L R+++ + + E + + I+ + LE I V+R+ K
Sbjct: 1042 NFEHRIEDLTRQLRNSTLQCETINSDNEDLLARIETLQSNAKLLEVQILEVQRA-----K 1096
Query: 329 RLQDKEQELEQLTKELRQVNLQQFIQQTGTKVTVLPAEPIEIEASHADIER 379
+ DKE E E+L KE Q I++ T V L ++++ +++
Sbjct: 1097 AMVDKELEAEKLQKE-------QKIKEHATTVNELEELQVQLQKEKKQLQK 1140
Score = 37.0 bits (84), Expect = 0.031
Identities = 80/355 (22%), Positives = 146/355 (41%), Gaps = 82/355 (23%)
Query: 68 QYASDVQLILRRTGPSLSERPTS-DSVARIPERTLYRQSLPPLAKLRPQIDKSIKRREPK 126
Q ASDV + ++ + +E+ ++V R+ + L +L P+++ +IK + K
Sbjct: 511 QQASDVHELQQKLRTAFTEKDALLETVNRLQGEN---EKLLSQQELVPELENTIKNLQEK 567
Query: 127 RKSLTFTGGAKGLMDIFGKGKETEFKQKVLNNCKTTADELKKLIRLQTEKLQSIEKQLES 186
+ + M KE E K +N+ D+ ++ E++ + K+ E
Sbjct: 568 NGVYLLSLSQRDTML-----KELEGK---INSLTEEKDDFINKLKNSHEEMDNFHKKCER 619
Query: 187 NEIEIRFWEQK------YNSNLEEEIVR----LEQKIKRND--------------VEIEE 222
E I +K YNS LE+++ LE+ +K D V E+
Sbjct: 620 EERLILELGKKVEQTIQYNSELEQKVNELTGGLEETLKEKDQNDQKLEKLMVQMKVLSED 679
Query: 223 EEFWENELQ-IEQEN------EKQLKDQLQE---------IRQKITECENKLKDYLAQIR 266
+E E++ + +EN +KQL L+ +++ IT+ E KL+ + +
Sbjct: 680 KEVLSAEVKSLYEENNKLSSEKKQLSRDLEVFLSQKEDVILKEHITQLEKKLQLMVEEQD 739
Query: 267 TMESGLEAEKLQR----------------EVQEAQVNEEEVK---------GKIGKVKGE 301
+ LE E++Q+ EV E ++ V KI + K
Sbjct: 740 NLNKLLENEQVQKLFVKTQLYGFLKEMGSEVSEDSEEKDVVNVLQAVGESLAKINEEKCN 799
Query: 302 IDIQ-GQQSLRLENGIKAV-ERSLGQATK---RLQDKEQELEQLTKELRQVNLQQ 351
+ Q ++ L LE IK + E S+ Q + L+D EQE L KEL ++ ++
Sbjct: 800 LAFQRDEKVLELEKEIKCLQEESVVQCEELKSLLRDYEQEKVLLRKELEEIQSEK 854
Score = 36.6 bits (83), Expect = 0.040
Identities = 39/168 (23%), Positives = 80/168 (47%), Gaps = 36/168 (21%)
Query: 165 ELKKLIRLQTEKLQSIEKQLESNEIEIRFWEQKYNSNLEE------------EIVRLEQK 212
+L+K ++L E+ ++ K LE+ +++ F + + L+E ++V + Q
Sbjct: 726 QLEKKLQLMVEEQDNLNKLLENEQVQKLFVKTQLYGFLKEMGSEVSEDSEEKDVVNVLQA 785
Query: 213 IKRNDVEIEEEE----FWENELQIEQENEKQLKDQLQEIRQKITECENKLKDYLAQIRTM 268
+ + +I EE+ F +E +E E K++K +E + E ++ L+DY
Sbjct: 786 VGESLAKINEEKCNLAFQRDEKVLELE--KEIKCLQEESVVQCEELKSLLRDY------- 836
Query: 269 ESGLEAEK--LQREVQEAQVNEEEVKGKIGKVKGEIDIQGQQSLRLEN 314
E EK L++E++E Q +E ++ + ++K + RLEN
Sbjct: 837 ----EQEKVLLRKELEEIQSEKEALQSDLLEMK-----NANEKTRLEN 875
Score = 29.6 bits (65), Expect = 4.9
Identities = 56/246 (22%), Positives = 101/246 (41%), Gaps = 66/246 (26%)
Query: 166 LKKLIRLQTEKLQSIEKQLESNEIEIRFWEQKYNSNLEEEIVRLEQKIKRNDV-EIEEEE 224
+++++ + + L+ K+LES ++ E Y +NL+ ++ Q IK E E+ E
Sbjct: 326 VEQVVNEKVKHLEDTLKELESQHSILKD-EVTYMNNLKLKLEMDAQHIKDEFFHEREDLE 384
Query: 225 FWENELQIEQENE----KQLKDQL---------------------QEIRQK--------- 250
F NEL + +E + ++LK +L +E QK
Sbjct: 385 FKINELLLAKEEQGCVIEKLKSELAGLNKQFCYTVEQHNREVQSLKEQHQKEISELNETF 444
Query: 251 ITECENKLKDYLAQIRTMESGLEAEKLQREVQEAQVNEE-----------EVKGKIGKVK 299
+++ E + + +I+ ++ + E LQ+E QEA +N E E+ GK+
Sbjct: 445 LSDSEKEKLTLMFEIQGLKE--QCENLQQEKQEAILNYESLREIMEILQTELGESAGKIS 502
Query: 300 GEIDIQGQQSL--------RLENG-------IKAVERSLGQATKRLQDKE--QELEQLTK 342
E + QQ +L ++ V R G+ K L +E ELE K
Sbjct: 503 QEFESMKQQQASDVHELQQKLRTAFTEKDALLETVNRLQGENEKLLSQQELVPELENTIK 562
Query: 343 ELRQVN 348
L++ N
Sbjct: 563 NLQEKN 568
Score = 28.9 bits (63), Expect = 8.4
Identities = 33/128 (25%), Positives = 52/128 (40%), Gaps = 9/128 (7%)
Query: 178 QSIEKQLESNEIEIR--FWEQKYNSNLEEEIVRLEQKIKRNDVEIEEEEFWENELQIEQE 235
QS+E+ L S E ++ W ++ EE + +L K D E I E
Sbjct: 1534 QSLEQLLNSPETKLEPPLWHAEFTK--EELVQKLSSTTKSADHLNGLLRETEATNAILME 1591
Query: 236 NEKQLKDQLQEI-----RQKITECENKLKDYLAQIRTMESGLEAEKLQREVQEAQVNEEE 290
K LK +++ + R+K LK+ L Q ++ G E E+L + E
Sbjct: 1592 QIKLLKSEIRRLERNQEREKSAANLEYLKNVLLQFIFLKPGSERERLLPVINTMLQLSPE 1651
Query: 291 VKGKIGKV 298
KGK+ V
Sbjct: 1652 EKGKLAAV 1659
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 60.1 bits (144), Expect = 3e-09
Identities = 55/287 (19%), Positives = 137/287 (47%), Gaps = 30/287 (10%)
Query: 111 KLRPQIDKSIKRREPKRKSLTFTGGAKGLMDIFGKGKETEFKQKVLNNCKTTADELKKLI 170
KLR + + +K L + A D+ + +E L + T D+L+ ++
Sbjct: 1739 KLRGIVSEKTNEISNMQKDLEHSNDALKAQDLKIQ-EELRIAHMHLKEQQETIDKLRGIV 1797
Query: 171 RLQTEKLQSIEKQLESNEIEIRFWEQKYNSNLEEEIVRLEQKIKRNDVEIEEEEFWENEL 230
+T+KL +++K LE++ +++ Q+ +N E +++ L++ + ++ E E + ++
Sbjct: 1798 SEKTDKLSNMQKDLENSNAKLQEKIQELKAN-EHQLITLKKDVNETQKKVSEMEQLKKQI 1856
Query: 231 QIEQENEKQLKDQLQEIRQKITECENKLKDYLAQ---IRTMESGLEAEK----------- 276
+ + +L+ + + QK+ E ++K + + +R +E L+ E+
Sbjct: 1857 KDQSLTLSKLEIENLNLAQKLHENLEEMKSVMKERDNLRRVEETLKLERDQLKESLQETK 1916
Query: 277 -----LQREVQEAQVNEEEVKGKIGKVKGEIDIQGQQSLRLENGIKAVERSLGQATKRLQ 331
+Q+E++ A++ +E K + K++ +I + Q I +++ L ++ LQ
Sbjct: 1917 ARDLEIQQELKTARMLSKEHKETVDKLREKISEKTIQ-------ISDIQKDLDKSKDELQ 1969
Query: 332 DKEQELEQLTKELRQVNLQQFIQQTGTKVTVLPAEPIEIEASHADIE 378
K QEL++ KEL+ + +++ + + K+ + + EA + ++
Sbjct: 1970 KKIQELQK--KELQLLRVKEDVNMSHKKINEMEQLKKQFEAQNLSMQ 2014
Score = 55.1 bits (131), Expect = 1e-07
Identities = 56/240 (23%), Positives = 116/240 (48%), Gaps = 30/240 (12%)
Query: 137 KGLMDIFGKGKETEFKQKVLNNC----KTTADELKKLIRLQTEKLQSIEKQLESNEIEIR 192
+ + +I K ETE + KV + C + T +EL+ + + ++ +I+KQLE+
Sbjct: 1463 ENIKEIVAKHLETEEELKVAHCCLKEQEETINELRVNLSEKETEISTIQKQLEA------ 1516
Query: 193 FWEQKYNSNLEEEIVRLEQKIKRNDV-EIEEEEFWENELQIEQENEKQLKDQLQEIRQKI 251
N L+ +I + +K ++ ++ +I E + NEL+ +E+ K LQ I K+
Sbjct: 1517 -----INDKLQNKIQEIYEKEEQFNIKQISEVQEKVNELKQFKEHRKAKDSALQSIESKM 1571
Query: 252 TECENKLKDYLAQIRTMESGLEAEKLQREVQEAQVNEEEVKGKIGKVKGEIDIQGQQSLR 311
E N+L++ +I+ M E E+++R + Q+ +++K ++ ++
Sbjct: 1572 LELTNRLQESQEEIQIMIK--EKEEMKRVQEALQIERDQLKENTKEIVAKMK-------- 1621
Query: 312 LENGIKAVERSLGQATKRLQDKEQELEQLTK--ELRQVNLQQFIQQTGTKVTVLPAEPIE 369
E+ K + A Q+K E+E L + E +++NL+ I+ ++T + E +E
Sbjct: 1622 -ESQEKEYQFLKMTAVNETQEKMCEIEHLKEQFETQKLNLEN-IETENIRLTQILHENLE 1679
Score = 50.4 bits (119), Expect = 3e-06
Identities = 51/226 (22%), Positives = 111/226 (49%), Gaps = 38/226 (16%)
Query: 164 DELKKLIRLQTEKLQSIEKQLESNEI-----EIRFWEQKYNS--NLEEEIVRLEQKIKRN 216
+ L K+ Q+++ QS+ + + NE E+ ++ K ++ +E E++ L ++++ +
Sbjct: 1374 ETLAKIQESQSKQEQSLNMKEKDNETTKIVSEMEQFKPKDSALLRIEIEMLGLSKRLQES 1433
Query: 217 DVEIEEEEFWENELQ----IEQENEKQLKDQLQEIRQKITECENKLK------------- 259
E++ +++LQ + Q QLK+ ++EI K E E +LK
Sbjct: 1434 HDEMKSVAKEKDDLQRLQEVLQSESDQLKENIKEIVAKHLETEEELKVAHCCLKEQEETI 1493
Query: 260 --------DYLAQIRTMESGLEA--EKLQREVQEAQVNEEEVKGK-IGKVKGEIDIQGQ- 307
+ +I T++ LEA +KLQ ++QE EE+ K I +V+ +++ Q
Sbjct: 1494 NELRVNLSEKETEISTIQKQLEAINDKLQNKIQEIYEKEEQFNIKQISEVQEKVNELKQF 1553
Query: 308 --QSLRLENGIKAVERSLGQATKRLQDKEQELEQLTKELRQVNLQQ 351
++ ++++E + + T RLQ+ ++E++ + KE ++ Q
Sbjct: 1554 KEHRKAKDSALQSIESKMLELTNRLQESQEEIQIMIKEKEEMKRVQ 1599
Score = 49.7 bits (117), Expect = 5e-06
Identities = 49/216 (22%), Positives = 103/216 (47%), Gaps = 44/216 (20%)
Query: 181 EKQLESNEIEIRFWEQKYN-SNLEEEIVRLEQKIKRN-------------------DVEI 220
EK E ++ +F QK N N+E E +RL Q + N +++
Sbjct: 1641 EKMCEIEHLKEQFETQKLNLENIETENIRLTQILHENLEEMRSVTKERDDLRSVEETLKV 1700
Query: 221 EEEEFWEN-------------ELQIEQENEKQLKDQLQEIRQKITECENKLKDYLAQIRT 267
E ++ EN EL+I + K+ ++ + ++R ++E N++ + +
Sbjct: 1701 ERDQLKENLRETITRDLEKQEELKIVHMHLKEHQETIDKLRGIVSEKTNEISNMQKDLEH 1760
Query: 268 MESGLEAE--KLQREVQEAQVNEEEVKGKIGKVKGEIDIQGQQSLRLENGIKAVERSLGQ 325
L+A+ K+Q E++ A ++ +E + I K++G I +++ +L N +++ L
Sbjct: 1761 SNDALKAQDLKIQEELRIAHMHLKEQQETIDKLRG---IVSEKTDKLSN----MQKDLEN 1813
Query: 326 ATKRLQDKEQELEQLTKELRQVNLQQFIQQTGTKVT 361
+ +LQ+K QEL+ E + + L++ + +T KV+
Sbjct: 1814 SNAKLQEKIQELK--ANEHQLITLKKDVNETQKKVS 1847
Score = 45.1 bits (105), Expect = 1e-04
Identities = 49/227 (21%), Positives = 101/227 (44%), Gaps = 15/227 (6%)
Query: 137 KGLMDIFGKGKETEFKQKVLNNCKTTADELKKLIRLQTEKLQSIEKQLESNE------IE 190
+GL++ GK K+ + +N K+T E + L + Q + LE NE +
Sbjct: 792 QGLLEEIGKTKDDLATTQ--SNYKSTDQEFQNFKTLHMDFEQKYKMVLEENERMNQEIVN 849
Query: 191 IRFWEQKYNSNLEEEIVRLEQKIKRNDVEIEEEEFWENELQIEQENEKQLKDQLQEIRQK 250
+ QK++S+L L K + + E + NE++ +E + LQ + ++
Sbjct: 850 LSKEAQKFDSSLGALKTELSYKTQELQEKTREVQERLNEMEQLKEQLENRDSTLQTVERE 909
Query: 251 ITECENKLKDYLAQIRTMESGLEAEKLQREVQEAQVNEEEVKGKI-GKVKGEIDIQGQQS 309
T KL+ L +++T+ E + L++ + Q+ +++K I V ID Q Q
Sbjct: 910 KTLITEKLQQTLEEVKTLTQ--EKDDLKQLQESLQIERDQLKSDIHDTVNMNIDTQEQLR 967
Query: 310 LRLENGIKAVERSLGQATKRLQD---KEQELEQLTKELRQVNLQQFI 353
LE+ +K + ++ ++ + + +E+ T E + Q+ +
Sbjct: 968 NALES-LKQHQETINTLKSKISEEVSRNLHMEENTGETKDEFQQKMV 1013
Score = 44.7 bits (104), Expect = 1e-04
Identities = 59/272 (21%), Positives = 125/272 (45%), Gaps = 50/272 (18%)
Query: 139 LMDIFGKGKETEFKQKV----LNNCKTTADELKKLIRLQTEKLQSIEKQLESNEIEIRFW 194
+ +I G +T+ + K+ L + T DEL++ + +T ++ + + ++E
Sbjct: 1223 IREIEATGLQTKEELKIAHIHLKEHQETIDELRRSVSEKTAQI------INTQDLE---- 1272
Query: 195 EQKYNSNLEEEIVRL--EQKIKRNDVEIEEEEFWENELQI--EQENEK------QLKDQL 244
K ++ L+EEI L EQ++ N E+ E + NEL++ EQ K +++ +
Sbjct: 1273 --KSHTKLQEEIPVLHEEQELLPNVKEVSETQETMNELELLTEQSTTKDSTTLARIEMER 1330
Query: 245 QEIRQKITECENKLKDYLAQ---IRTMESGLEAE-------------KLQ--REVQEAQV 286
+ +K E + ++K + ++T++ LE + K+Q + QE +
Sbjct: 1331 LRLNEKFQESQEEIKSLTKERDNLKTIKEALEVKHDQLKEHIRETLAKIQESQSKQEQSL 1390
Query: 287 NEEEVKGKIGKVKGEIDIQGQQSLRLENGIKAVERSLGQATKRLQDKEQELEQLTKELRQ 346
N +E + K+ E++ Q ++ + +E + +KRLQ+ E++ + KE +
Sbjct: 1391 NMKEKDNETTKIVSEME----QFKPKDSALLRIEIEMLGLSKRLQESHDEMKSVAKE--K 1444
Query: 347 VNLQQFIQQTGTKVTVLPAEPIEIEASHADIE 378
+LQ+ + ++ L EI A H + E
Sbjct: 1445 DDLQRLQEVLQSESDQLKENIKEIVAKHLETE 1476
Score = 43.9 bits (102), Expect = 3e-04
Identities = 41/209 (19%), Positives = 103/209 (49%), Gaps = 13/209 (6%)
Query: 146 GKETEFKQKVLNNCKTTADELKKLIRLQTEKLQSIEKQLESNEIEIRFWEQKYNSNLEEE 205
G E + +Q+++ K A + + + ++L +E++L+ +++ +Q+ N++EE
Sbjct: 1091 GDELKKQQEIVAQEKNHAIKKEGELSRTCDRLAEVEEKLKEKSQQLQEKQQQL-LNVQEE 1149
Query: 206 IVRLEQKIKRNDVEIEEEEFWENELQIEQENEKQLKDQLQEIRQKITECENKLKDYLAQI 265
+ +++KI E E +NEL+ ++ + ++ + E+ QK+ E ++K +
Sbjct: 1150 MSEMQKKIN-------EIENLKNELKNKELTLEHMETERLELAQKLNENYEEVKSITKER 1202
Query: 266 RTMESGLEAEKLQREVQEAQVNEEEVKGKIGKVKGEIDIQGQQSLRLENGIKAVERSLGQ 325
+ ++ ++ + +R+ + E E G + K E+ I + I + RS+ +
Sbjct: 1203 KVLKELQKSFETERDHLRGYIREIEATGL--QTKEELKIAHIHLKEHQETIDELRRSVSE 1260
Query: 326 ATKRL---QDKEQELEQLTKELRQVNLQQ 351
T ++ QD E+ +L +E+ ++ +Q
Sbjct: 1261 KTAQIINTQDLEKSHTKLQEEIPVLHEEQ 1289
Score = 40.8 bits (94), Expect = 0.002
Identities = 48/216 (22%), Positives = 95/216 (43%), Gaps = 25/216 (11%)
Query: 147 KETEFKQKVLNNCKTTADELKKLIRLQTEKLQSIEKQLESNEIEIRFWEQKYNSNLEEEI 206
KE + ++V K D+LK+ LQ K + +E Q E + E K E +
Sbjct: 1889 KERDNLRRVEETLKLERDQLKE--SLQETKARDLEIQQELKTARMLSKEHK------ETV 1940
Query: 207 VRLEQKIKRNDVEIEE--------EEFWENELQIEQENEKQL---KDQLQEIRQKITECE 255
+L +KI ++I + ++ + ++Q Q+ E QL K+ + +KI E E
Sbjct: 1941 DKLREKISEKTIQISDIQKDLDKSKDELQKKIQELQKKELQLLRVKEDVNMSHKKINEME 2000
Query: 256 NKLKDYLAQIRTMESGLE-----AEKLQREVQEAQVNEEEVKGKIGKVKGEIDIQGQQSL 310
K + AQ +M+S +KL ++E ++ +E + ++ ++K + ++ Q +
Sbjct: 2001 QLKKQFEAQNLSMQSVRMDNFQLTKKLHESLEEIRIVAKE-RDELRRIKESLKMERDQFI 2059
Query: 311 RLENGIKAVERSLGQATKRLQDKEQELEQLTKELRQ 346
+ A +R Q + + LT+ LR+
Sbjct: 2060 ATLREMIARDRQNHQVKPEKRLLSDGQQHLTESLRE 2095
Score = 39.7 bits (91), Expect = 0.005
Identities = 50/243 (20%), Positives = 105/243 (43%), Gaps = 40/243 (16%)
Query: 143 FGKGKETEFKQKVLNNCKTTADELKKLIRLQTEKLQS-------IEKQLESNEIEIRFWE 195
F + + E K+K + TT +++ I+L +L++ +EK+L+S EI
Sbjct: 643 FLRSENLELKEK-MKELATTYKQMENDIQLYQSQLEAKKKMQVDLEKELQSAFNEITKLT 701
Query: 196 QKYNSNLEEEIV---RLEQKI----KRNDVEIEEEEFWENELQIEQENE----------K 238
+ + ++++ LE KI K + E+EE E E+ + E + K
Sbjct: 702 SLIDGKVPKDLLCNLELEGKITDLQKELNKEVEENEALREEVILLSELKSLPSEVERLRK 761
Query: 239 QLKDQLQEIR----------QKITECENKLKDYLAQIRTMESGLEA-----EKLQREVQE 283
+++D+ +E+ ++ E++++ L +I + L + +E Q
Sbjct: 762 EIQDKSEELHIITSEKDKLFSEVVHKESRVQGLLEEIGKTKDDLATTQSNYKSTDQEFQN 821
Query: 284 AQVNEEEVKGKIGKVKGEIDIQGQQSLRLENGIKAVERSLGQATKRLQDKEQELEQLTKE 343
+ + + K V E + Q+ + L + + SLG L K QEL++ T+E
Sbjct: 822 FKTLHMDFEQKYKMVLEENERMNQEIVNLSKEAQKFDSSLGALKTELSYKTQELQEKTRE 881
Query: 344 LRQ 346
+++
Sbjct: 882 VQE 884
Score = 39.3 bits (90), Expect = 0.006
Identities = 61/273 (22%), Positives = 119/273 (43%), Gaps = 53/273 (19%)
Query: 149 TEFKQKVLNNCKTTADELKKLIRLQTEKLQSIEKQLESN-----EIEIRFWEQKYN---- 199
TE Q+ L KT E L +LQ E LQ QL+S+ + I EQ N
Sbjct: 914 TEKLQQTLEEVKTLTQEKDDLKQLQ-ESLQIERDQLKSDIHDTVNMNIDTQEQLRNALES 972
Query: 200 ------------SNLEEEIVR--------------LEQKI----KRNDVEIEEEEFW--- 226
S + EE+ R +QK+ K+ D+E + +
Sbjct: 973 LKQHQETINTLKSKISEEVSRNLHMEENTGETKDEFQQKMVGIDKKQDLEAKNTQTLTAD 1032
Query: 227 --ENELQIEQENEK----QLKDQLQEIRQKITECENKLKDYLAQI--RTMESGLEAEKLQ 278
+NE+ IEQ+ + Q K++LQ++ + + + +LK L + T+E+ E L
Sbjct: 1033 VKDNEI-IEQQRKIFSLIQEKNELQQMLESVIAEKEQLKTDLKENIEMTIENQEELRLLG 1091
Query: 279 REVQEAQVNEEEVKGKIGKVKGEIDIQGQQSLRLENGIKAVERSLGQATKRLQDKEQELE 338
E+++ Q + K K +GE+ + +E +K + L + ++L + ++E+
Sbjct: 1092 DELKKQQEIVAQEKNHAIKKEGELSRTCDRLAEVEEKLKEKSQQLQEKQQQLLNVQEEMS 1151
Query: 339 QLTKELRQV-NLQQFIQQTGTKVTVLPAEPIEI 370
++ K++ ++ NL+ ++ + + E +E+
Sbjct: 1152 EMQKKINEIENLKNELKNKELTLEHMETERLEL 1184
Score = 35.8 bits (81), Expect = 0.068
Identities = 38/189 (20%), Positives = 95/189 (50%), Gaps = 16/189 (8%)
Query: 171 RLQTEKLQSIEKQLESNEI-EIRFWEQKYNSNLEEEIVRLEQKIKR--NDVEIEEEEFWE 227
+L+TEK + K E N++ E E+K + E +++ +K E+ ++ E
Sbjct: 516 QLRTEKEEMELKLKEKNDLDEFEALERKTKKDQEMQLIHEISNLKNLVKHAEVYNQDL-E 574
Query: 228 NELQIEQENEKQLKDQLQEIRQKITECENKLKDYLAQIR-TMESGLEAEKLQREVQEAQV 286
NEL + E ++ +DQ++++++ I KL++ + ++ES + +++++ + +A+
Sbjct: 575 NELSSKVELLREKEDQIKKLQEYIDS--QKLENIKMDLSYSLESIEDPKQMKQTLFDAET 632
Query: 287 NEEEVKGKIGKVKGEIDIQGQQSLR--------LENGIKAVERSLGQATKRLQDKEQELE 338
+ K + ++ E +++ ++ ++ +EN I+ + L K D E+EL+
Sbjct: 633 VALDAKRESAFLRSE-NLELKEKMKELATTYKQMENDIQLYQSQLEAKKKMQVDLEKELQ 691
Query: 339 QLTKELRQV 347
E+ ++
Sbjct: 692 SAFNEITKL 700
>gi|229577185 epidermal growth factor receptor pathway substrate 15
isoform B [Homo sapiens]
Length = 582
Score = 59.3 bits (142), Expect = 6e-09
Identities = 40/164 (24%), Positives = 85/164 (51%), Gaps = 18/164 (10%)
Query: 194 WEQKYNSNLEEEIVRLEQKIKRNDVEIEEEEFWENELQIEQENEKQL---KDQLQEIRQK 250
W + +N+E+++ E IK+ E+++ ++E+Q E N ++L K Q+QE+ +
Sbjct: 30 WSSREKNNVEQDLKEKEDTIKQRTSEVQD---LQDEVQRENTNLQKLQAQKQQVQELLDE 86
Query: 251 ITECENKLKDYLAQIRT-------MESGLEAEKLQREVQEAQVNEEEVKGKIGKVKGEID 303
+ E + +L++ L ++R + S L+AE +E Q + EE + K + E+
Sbjct: 87 LDEQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEE-----LAKAREELS 141
Query: 304 IQGQQSLRLENGIKAVERSLGQATKRLQDKEQELEQLTKELRQV 347
Q++ LE +++ + L + LQD +QE+ + +L ++
Sbjct: 142 RLQQETAELEESVESGKAQLEPLQQHLQDSQQEISSMQMKLMEM 185
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 59.3 bits (142), Expect = 6e-09
Identities = 52/218 (23%), Positives = 108/218 (49%), Gaps = 36/218 (16%)
Query: 165 ELKKLIRLQTEKLQSIEKQLESNEIEIR-----FWEQKYNSNLEEEIVRLEQKIKRNDVE 219
E +K IR Q EK+ E++L E ++R W Q+ +E+ +R ++K R E
Sbjct: 283 EQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKE 342
Query: 220 I---------EEEEFWENELQIEQ-------------ENEKQLKDQLQEIR---QKITEC 254
+ +EE+ WE E ++ + E EKQ+++Q Q++R +++ E
Sbjct: 343 LREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQ 402
Query: 255 ENKLKDYLAQIRTMESGLEAEKLQREVQEAQVNEEEVKGKIGKVKGEIDIQGQQSLRLEN 314
+ +L++ ++R E E + RE ++ Q E++ + + K++ E I+ + E
Sbjct: 403 DERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIRER-----EK 457
Query: 315 GIKAVERSLGQATKRLQDKEQEL-EQLTKELRQVNLQQ 351
++ E ++ + +++Q +E+ + EQ KE +Q L +
Sbjct: 458 KMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPE 495
Score = 59.3 bits (142), Expect = 6e-09
Identities = 43/166 (25%), Positives = 87/166 (52%), Gaps = 8/166 (4%)
Query: 173 QTEKLQSIEKQLESNEIEIRFWEQKYNSNLEEEIVRLEQKIKRND-VEIEEEEFWENELQ 231
Q EKL EK E E + WEQ+ +EE+ E+K+ R + + +E++ WE E +
Sbjct: 496 QKEKLWEQEKMQEQEE---KIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEK 552
Query: 232 IEQENEKQLKDQLQEIRQKITECENKLKDYLAQIRTMESGLEAEKLQREVQEAQVNEEEV 291
+ ++ E+++ DQ + + +K E E K D ++R E E EK RE +E +EE
Sbjct: 553 M-RDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEE- 610
Query: 292 KGKIGKVKGEIDIQGQQSLRLENGIKAVERSLGQATKRLQDKEQEL 337
K+ + + ++ Q ++ E ++ E + + +++ ++E+++
Sbjct: 611 --KMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKM 654
Score = 58.9 bits (141), Expect = 8e-09
Identities = 42/183 (22%), Positives = 97/183 (53%), Gaps = 23/183 (12%)
Query: 165 ELKKLIRLQTEKLQSIEKQLESNEIEIRFWEQKYNSNLEEEIVRLEQKIKRNDVEIEEEE 224
E ++++R Q EK+Q E++++ E E+ WEQ+ +EE + +Q++ ++E+
Sbjct: 724 EEEEMMREQEEKMQEQEEKMQEQEEEM--WEQEEKMWEQEEKMWEQQRLPE-----QKEK 776
Query: 225 FWENELQIEQENEKQLKDQLQEIRQKITECENKLKDYLAQIRTMESGL--EAEKLQREVQ 282
WE+E EQE KI E E K++D ++R E + + EK++ + +
Sbjct: 777 LWEHEKMQEQE--------------KIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEE 822
Query: 283 EAQVNEEEVKGKIGKVKGEIDIQGQQSLRLENGIKAVERSLGQATKRLQDKEQELEQLTK 342
+ EE++ G+ K+ G+ + Q ++E ++ E + + ++++ +E+++ + +
Sbjct: 823 KMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMREQEE 882
Query: 343 ELR 345
++R
Sbjct: 883 KMR 885
Score = 57.0 bits (136), Expect = 3e-08
Identities = 54/267 (20%), Positives = 136/267 (50%), Gaps = 22/267 (8%)
Query: 103 RQSLPPLAKLRPQIDKSIKRREPKRKSLTFTGGAKGLMDIFGKGKETEFKQKV-LNNCKT 161
+++L ++ + D+ I+ +R +L+ + + K K E ++K+ L +
Sbjct: 182 QRALSAVSTRHKKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLPLAESEK 241
Query: 162 TADELK-KLIRLQTEKLQSIEKQLESNEIEIRFWEQ--------KYNSNLEEEIVRLEQK 212
+ +L K ++ + E+ + + Q+++N ++ W Q K EE++ R E++
Sbjct: 242 SEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEER 301
Query: 213 IKRNDVEI--EEEEFWENELQIEQENEKQLKDQLQEIRQKITECENKLKDYLAQIRTMES 270
++ + ++ +EE+ W E ++ +E EK+L++Q +E+R+ + +L++ Q++ E
Sbjct: 302 LREQEGKMREQEEKMWRQEKRL-REQEKELREQEKELRE-----QKELREQEEQMQEQEE 355
Query: 271 GL-EAEKLQREVQEAQVNEEEVKGKIGKVKGEIDIQGQQSLRLENGIKAVERSLGQATKR 329
+ E E+ RE +E +EE ++ + + ++ Q Q+ E + + L + +R
Sbjct: 356 KMWEQEEKMREQEEKMWRQEE---RLWEQEKQMREQEQKMRDQEERMWEQDERLREKEER 412
Query: 330 LQDKEQELEQLTKELRQVNLQQFIQQT 356
++++E+ EQ+ K + +Q+ ++T
Sbjct: 413 MREQEKMWEQVEKMREEKKMQEQEKKT 439
Score = 55.1 bits (131), Expect = 1e-07
Identities = 46/200 (23%), Positives = 104/200 (52%), Gaps = 11/200 (5%)
Query: 165 ELKKLIRLQTEKLQSIEKQLESNEI----EIRFWEQKYNSNLEEEIVRLEQKIKRNDVEI 220
E ++ +R Q EK+Q E+ + E + R EQK +E++ E+KI + +I
Sbjct: 461 EEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKI 520
Query: 221 -EEEEFWENELQI-EQENEKQLKDQLQEIRQKITECENKLKDYLAQIRTMESGLEAEKLQ 278
++EE W E ++ QE ++ +DQ+ E +K+ + E K+ D + R + E EK
Sbjct: 521 RDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWD--QEERMEKKTQEQEKKT 578
Query: 279 REVQEAQVNEEEVKGKIGKVKGEIDIQGQQSLRL---ENGIKAVERSLGQATKRLQDKEQ 335
+ +E EE ++ + K++ E ++ +Q ++ E ++ E + + +++Q++E+
Sbjct: 579 WDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEE 638
Query: 336 ELEQLTKELRQVNLQQFIQQ 355
++ + +++ + + + QQ
Sbjct: 639 KMWEQEEKMWEQEEKMWEQQ 658
Score = 52.4 bits (124), Expect = 7e-07
Identities = 49/223 (21%), Positives = 113/223 (50%), Gaps = 24/223 (10%)
Query: 147 KETEFKQKVLNNCKTTADELKKLIRLQTEKLQSIEKQLESNEI----EIRFWEQKYNSNL 202
+E E++Q+ L K E +K+ + Q EK+ E+++ E E + W Q+
Sbjct: 484 EEKEWQQQRLPEQKEKLWEQEKM-QEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQ 542
Query: 203 EEEIVRLEQKIKRNDVEIEEEEFWENELQIE---QENEKQLKDQLQEIR--QKITECENK 257
E+++ E+K++ +E++ W+ E ++E QE EK+ DQ +++R +++ E E K
Sbjct: 543 EDQMWEQEEKMRD-----QEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKK 597
Query: 258 LKDYLAQIRTMESGL--EAEKLQREVQEAQVNEEEVKGKIGKVKGEIDIQGQQSLRL--- 312
+++ +R E + + EK+Q + ++ EE+++ + K+ + + +Q ++
Sbjct: 598 MREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQ 657
Query: 313 ----ENGIKAVERSLGQATKRLQDKEQELEQLTKELRQVNLQQ 351
E K E Q +++Q++E+++ + K ++ Q+
Sbjct: 658 QRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQE 700
Score = 52.0 bits (123), Expect = 9e-07
Identities = 50/216 (23%), Positives = 104/216 (48%), Gaps = 29/216 (13%)
Query: 152 KQKVLNNCKTTADELKKLIRLQTEKLQSIEKQLESNEIEIRFWEQKYNSNLEEEIVRLEQ 211
+QK L + E ++ + Q EK++ E+++ E R WEQ E+++ EQ
Sbjct: 339 EQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQ--EERLWEQ------EKQMREQEQ 390
Query: 212 KIKRNDVEIEEEEFWENELQIEQENEK-----QLKDQLQEIRQ--KITECENKLKDYLAQ 264
K++ +EE WE + ++ ++ E+ ++ +Q++++R+ K+ E E K +D +
Sbjct: 391 KMRD-----QEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEK 445
Query: 265 IRTMESGLEAEKLQREVQEAQVNEEEVKGKIGKVKGEIDIQGQQSLRL---------ENG 315
++ E E EK RE +E +EE K + E + + Q RL +
Sbjct: 446 MQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEK 505
Query: 316 IKAVERSLGQATKRLQDKEQELEQLTKELRQVNLQQ 351
++ E + + ++++D+E+ Q K RQ +++
Sbjct: 506 MQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMRE 541
Score = 52.0 bits (123), Expect = 9e-07
Identities = 43/193 (22%), Positives = 101/193 (52%), Gaps = 26/193 (13%)
Query: 165 ELKKLIRLQTEKLQSIEKQLESNEIEIRFWEQKYNSNLEEEIVRLEQKIKRNDVEI--EE 222
E ++++R Q EK+Q E++++ E E + WEQ EE++ E+K+ + ++ +E
Sbjct: 600 EEEEMMREQEEKMQEQEEKMQ--EQEEKMWEQ------EEKMQEQEEKMWEQEEKMWEQE 651
Query: 223 EEFWENELQIEQENEKQLKDQLQEIRQKITECENKLKDYLAQIRTMESGLEAEKLQREVQ 282
E+ WE + EQ+ + +++QE ++K+ E E K+ + ME + ++ + Q
Sbjct: 652 EKMWEQQRLPEQKEKLWEHEKMQE-QEKMQEQEEKIWEQ----EKMEKKTQEQEKKTWDQ 706
Query: 283 EAQVNEEEVKGKIGKVKGEIDIQGQQSLRLENGIKAVERSLGQATKRLQDKEQELEQLTK 342
E EE ++ + K++ E ++ +Q E + + +++Q++E+E+ + +
Sbjct: 707 EKMREEESMREREKKMREEEEMMREQ-----------EEKMQEQEEKMQEQEEEMWEQEE 755
Query: 343 ELRQVNLQQFIQQ 355
++ + + + QQ
Sbjct: 756 KMWEQEEKMWEQQ 768
Score = 51.2 bits (121), Expect = 2e-06
Identities = 40/184 (21%), Positives = 97/184 (52%), Gaps = 12/184 (6%)
Query: 173 QTEKLQSIEKQLESNEIEI-----RFWEQKYNSNLEEEIVRLEQKIKRNDVEIEEEEFWE 227
Q EK+Q E+++ E ++ + WEQ+ +E++ E+ ++ ++ +EE+ WE
Sbjct: 629 QEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWE 688
Query: 228 NELQIE--QENEKQLKDQLQEIRQK--ITECENKLKDYLAQIRTMESGLEA--EKLQREV 281
E + QE EK+ DQ +++R++ + E E K+++ +R E ++ EK+Q +
Sbjct: 689 QEKMEKKTQEQEKKTWDQ-EKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQE 747
Query: 282 QEAQVNEEEVKGKIGKVKGEIDIQGQQSLRLENGIKAVERSLGQATKRLQDKEQELEQLT 341
+E EE++ + K+ + + Q+ E+ + + + ++++D+E+++
Sbjct: 748 EEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQE 807
Query: 342 KELR 345
+++R
Sbjct: 808 EKMR 811
Score = 47.8 bits (112), Expect = 2e-05
Identities = 43/185 (23%), Positives = 90/185 (48%), Gaps = 17/185 (9%)
Query: 173 QTEKLQSIEKQLESNEIEIRFWEQKYNSNLEEEIVRLEQKIKRNDVEI----------EE 222
Q EK++ EK+++ E + R E+K EEE +R +K R + E +E
Sbjct: 422 QVEKMRE-EKKMQEQEKKTRDQEEKMQ---EEERIREREKKMREEEETMREQEEKMQKQE 477
Query: 223 EEFWE-NELQIEQENEKQLKDQLQEIRQKITECENKLKDYLAQIRTMESGLEAEKLQREV 281
E WE E + +Q+ + K++L E ++K+ E E K+ + +IR E EK
Sbjct: 478 ENMWEQEEKEWQQQRLPEQKEKLWE-QEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQ 536
Query: 282 QEAQVNEEEVKGKIGKVKGEIDIQGQQSLRLENGIKAVERSLGQATKRLQDKEQELEQLT 341
++ + E+++ + K++ + Q R+E + E+ +++++ E+ + +
Sbjct: 537 EKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMRE-EERMRERE 595
Query: 342 KELRQ 346
K++R+
Sbjct: 596 KKMRE 600
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 58.9 bits (141), Expect = 8e-09
Identities = 43/176 (24%), Positives = 90/176 (51%), Gaps = 5/176 (2%)
Query: 170 IRLQTEKLQSIEKQLESNEIEIRFWEQKYNSNLEEEIVRLEQKIKRNDVEIEEEEFWENE 229
++ + ++LQ +++ + E E++ EQK++ EE+ + EQ ++ E EE
Sbjct: 854 MQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRL 913
Query: 230 LQIEQENEK---QLKDQLQEIRQKITECENKLKDYLAQIRTMESGLEAEKLQREVQEAQV 286
+QE E+ +++ +L+E + + + + K Q+ +E LE E+ R Q+ Q+
Sbjct: 914 AAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAAR--QKLQL 971
Query: 287 NEEEVKGKIGKVKGEIDIQGQQSLRLENGIKAVERSLGQATKRLQDKEQELEQLTK 342
+ + KI K++ EI + Q+ +L K +E + T L ++E++ + LTK
Sbjct: 972 EKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTK 1027
Score = 51.6 bits (122), Expect = 1e-06
Identities = 60/246 (24%), Positives = 104/246 (42%), Gaps = 31/246 (12%)
Query: 109 LAKLRPQIDKSIKRREPKRKSLT------------FTGGAKGLMDIFGKGKETEFKQKVL 156
L L Q D +IK RE K L +IF KE E K K L
Sbjct: 1626 LKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSL 1685
Query: 157 NNCKTTADELKKLIRLQTEKLQSIEKQLESNEIEIRFWEQKYNSN-LEEEIVRLEQKIKR 215
AD ++ L + + LE E+ N L++E RLE +I +
Sbjct: 1686 E-----ADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQ 1740
Query: 216 NDVEIEEEEFWENELQIEQENEKQLKDQLQEIRQKITECENKLKDYLAQIRTMESGLEAE 275
+ E+EE EQ N + + D++++ Q+ + N+L + + ES +
Sbjct: 1741 LEEELEE----------EQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESA--RQ 1788
Query: 276 KLQREVQEAQVNEEEVKGKI-GKVKGEIDIQGQQSLRLENGIKAVERSLGQATKRLQDKE 334
+L+R+ +E + E++G + K K I + +LE ++ R ATK L+ K+
Sbjct: 1789 QLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKD 1848
Query: 335 QELEQL 340
++L+++
Sbjct: 1849 KKLKEI 1854
Score = 49.3 bits (116), Expect = 6e-06
Identities = 59/277 (21%), Positives = 130/277 (46%), Gaps = 27/277 (9%)
Query: 110 AKLRPQIDKSIKRREPKRKSLTFTGGAKGLMDIFGKGKETEFKQKVLNNCKTTAD-ELKK 168
A+L + D+ + + ++K A+ ++D+ + +E E ++ L K TA+ ++KK
Sbjct: 929 ARLEEEEDRGQQLQAERKKM------AQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKK 982
Query: 169 LIRLQTEKLQSIEKQLESNEIEIRFWEQKYNSNLEEEIVRLEQKIKRNDVEIEEEEFWEN 228
L +++ ++ Q E + E++ S+L + E+K K + E +
Sbjct: 983 L----EDEILVMDDQNNKLSKERKLLEERI-SDLTTNLAEEEEKAKNLTKLKNKHESMIS 1037
Query: 229 ELQIEQENEKQLKDQLQEIRQKITECENKLKDYLAQIRTMESGLEAEKLQREVQEAQVN- 287
EL++ + E++ + +L+++++K+ E D+ QI +++ + K+Q +E ++
Sbjct: 1038 ELEVRLKKEEKSRQELEKLKRKL---EGDASDFHEQIADLQAQIAELKMQLAKKEEELQA 1094
Query: 288 -----EEEVKGKIGKVKGEIDIQGQQSLRLENGIKAVERSLGQATKRLQDKEQELEQLTK 342
++E+ K +K +++G S L+ + + + +A K+ +D +ELE L
Sbjct: 1095 ALARLDDEIAQKNNALKKIRELEGHIS-DLQEDLDSERAARNKAEKQKRDLGEELEALKT 1153
Query: 343 ELRQ-----VNLQQFIQQTGTKVTVLPAEPIEIEASH 374
EL Q+ + +VTVL E SH
Sbjct: 1154 ELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSH 1190
Score = 45.4 bits (106), Expect = 9e-05
Identities = 41/213 (19%), Positives = 101/213 (47%), Gaps = 15/213 (7%)
Query: 146 GKETEFKQKVLNNCKTTADELKKLIRLQTEKLQSIEKQLESNEIEIRFWEQKYNSNLEEE 205
GK +K +T +E+K + ++LQ+ E E+ ++ + ++ +L+
Sbjct: 1524 GKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQAR 1583
Query: 206 IVRLEQKIKRNDVEIEEEEFWENELQIEQEN-------EKQLKDQLQEIRQKITECENKL 258
+ E+K ++ ++ E +E EL+ E++ +K+L+ L+++ +
Sbjct: 1584 DEQNEEKRRQLQRQLHE---YETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGR 1640
Query: 259 KDYLAQIRTMESGLEAEKLQREVQEAQVNEEEVKGKIGKVKGEIDIQGQQSLRLENGIKA 318
++ + Q+R +++ + + QRE+++A+ + +E+ + + + ++L+ + A
Sbjct: 1641 EEAIKQLRKLQA--QMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAA 1698
Query: 319 VERSLGQATKRLQDKEQELEQLTKELRQVNLQQ 351
ER+ QA +KE+ E+L L N Q
Sbjct: 1699 AERARKQAD---LEKEELAEELASSLSGRNALQ 1728
Score = 44.7 bits (104), Expect = 1e-04
Identities = 48/199 (24%), Positives = 93/199 (46%), Gaps = 33/199 (16%)
Query: 178 QSIEKQLESNEIEIRFWEQKYNSNLEEEIVRLEQKIKRNDVEIEEEEFWENELQIEQENE 237
++++++ S+E +++ QK+ +EE +LEQ KR +++ N+ +E+EN
Sbjct: 1181 KALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQ-FKRAKANLDK-----NKQTLEKENA 1234
Query: 238 KQLKDQLQEIRQKITECENKLKDYLAQIRTMESGL------------EAEKLQREVQEAQ 285
L +L+ + Q E E+K K AQ++ ++S + KLQ EV+
Sbjct: 1235 -DLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVT 1293
Query: 286 VNEEEVKGKIGKVKGEI--------DIQG--QQSLRLENGIKAVERSLGQATKRLQDK-E 334
E +GK K+ ++ D Q Q+ R + + R L + LQD+ +
Sbjct: 1294 GMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLD 1353
Query: 335 QELE---QLTKELRQVNLQ 350
+E+E L + + +N+Q
Sbjct: 1354 EEMEAKQNLERHISTLNIQ 1372
Score = 42.4 bits (98), Expect = 7e-04
Identities = 43/161 (26%), Positives = 78/161 (48%), Gaps = 24/161 (14%)
Query: 234 QENEKQLK-DQLQEIRQKITECENKLKDYLAQIR---TMESGLEAEKLQREVQEAQVNEE 289
QE E Q K D+LQ+ +++ + EN+LK+ L Q T E L E+LQ E E E
Sbjct: 850 QEEEMQAKEDELQKTKERQQKAENELKE-LEQKHSQLTEEKNLLQEQLQAET-ELYAEAE 907
Query: 290 EVKGKIGKVKGEI-DIQGQQSLRLENGIKAVERSLGQATKRLQDKEQELEQLTKELRQ-- 346
E++ ++ K E+ +I + RLE +D+ Q+L+ K++ Q
Sbjct: 908 EMRVRLAAKKQELEEILHEMEARLEEE---------------EDRGQQLQAERKKMAQQM 952
Query: 347 VNLQQFIQQTGTKVTVLPAEPIEIEASHADIERGIIILSDK 387
++L++ +++ L E + EA +E I+++ D+
Sbjct: 953 LDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQ 993
Score = 42.4 bits (98), Expect = 7e-04
Identities = 41/177 (23%), Positives = 77/177 (43%), Gaps = 23/177 (12%)
Query: 171 RLQTEKLQSIEKQLESNEIEIRF----WEQKYNSNLEEEIVRLEQKIKRNDVEIEEEEFW 226
R +K +S +QLE E+R E S + I LE KI + + ++E+E
Sbjct: 1777 RSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEARE 1836
Query: 227 EN--------------ELQIEQENEKQLKDQLQEIRQKITECENKLKDYLAQIRTMESGL 272
+ E+ ++ E+E+++ +Q +E +K +LK L + +
Sbjct: 1837 KQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRI 1896
Query: 273 EA--EKLQREVQEAQVNEEEVKGKIGKVKGEIDIQGQQSL---RLENGIKAVERSLG 324
A KLQRE+ EA + E + ++ +K ++ + S R G + +E + G
Sbjct: 1897 NANRRKLQRELDEATESNEAMGREVNALKSKLRRGNETSFVPSRRSGGRRVIENADG 1953
Score = 41.6 bits (96), Expect = 0.001
Identities = 41/204 (20%), Positives = 91/204 (44%), Gaps = 30/204 (14%)
Query: 148 ETEFKQKVLNNCKTTADELKKLIRLQTEKLQSIEKQLESNEIEIRFWEQKYNSNLEEEIV 207
E E +LN + A +L K + + +LQ ++ L+ E + N+ ++
Sbjct: 1288 EVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQE--------ETRQKLNVSTKLR 1339
Query: 208 RLEQKIKRNDVEIEEEEFWENELQIEQENEKQLKDQLQEIRQKITECENKLKDYLAQIRT 267
+LE EE +++L E E ++ L+ + + ++++ + KL+D+ + +
Sbjct: 1340 QLE----------EERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEA 1389
Query: 268 MESGLEAEKLQREVQEAQVNEEE---VKGKIGKVKGEIDIQGQQSLRLENGIKAVERSLG 324
+E G ++ Q+E++ EE K+ K K + QQ L + + +
Sbjct: 1390 LEEG--KKRFQKEIENLTQQYEEKAAAYDKLEKTKNRL----QQEL---DDLVVDLDNQR 1440
Query: 325 QATKRLQDKEQELEQLTKELRQVN 348
Q L+ K+++ +QL E + ++
Sbjct: 1441 QLVSNLEKKQRKFDQLLAEEKNIS 1464
Score = 40.8 bits (94), Expect = 0.002
Identities = 38/195 (19%), Positives = 88/195 (45%), Gaps = 33/195 (16%)
Query: 153 QKVLNNCKTTADELKKLIRLQTEKLQSIEKQLESNEIEIRFWEQKYNSNLEEEIVRLEQK 212
Q+ L++ + ++ +K R E+L++++ +LE ++ +Q+ + E+E+ L++
Sbjct: 1124 QEDLDSERAARNKAEKQKRDLGEELEALKTELEDT-LDSTATQQELRAKREQEVTVLKKA 1182
Query: 213 IKRNDVEIEEEEFWENELQIEQENEKQLKDQLQEIRQKITECENKLKDYLAQIRTMESGL 272
+ +EE +E Q+ QE+RQK + +L + L Q + ++ L
Sbjct: 1183 L--------DEETRSHEAQV------------QEMRQKHAQAVEELTEQLEQFKRAKANL 1222
Query: 273 EAEKLQREVQEAQVNEEEVKGKIGKVKGEIDIQGQQSLRLENGIKAVERSLGQATKRLQD 332
+ K E + A + GE+ + GQ +E+ K +E + + + D
Sbjct: 1223 DKNKQTLEKENAD------------LAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSD 1270
Query: 333 KEQELEQLTKELRQV 347
E+ +L ++ ++
Sbjct: 1271 GERARAELNDKVHKL 1285
Score = 40.8 bits (94), Expect = 0.002
Identities = 43/208 (20%), Positives = 95/208 (45%), Gaps = 14/208 (6%)
Query: 147 KETEFKQKVLNNCKTTADEL---KKLIRLQTEKLQSIEKQLESNEIEIRFWEQKYNSN-- 201
+E E KQ + + T +L KK ++ ++++E+ + + EI Q+Y
Sbjct: 1354 EEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAA 1413
Query: 202 ----LEEEIVRLEQKIKRNDVEIEEEEFWENELQIEQENEKQLKDQLQEIRQKITECENK 257
LE+ RL+Q++ V+++ + + L+ +Q QL + + I K + ++
Sbjct: 1414 AYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDR 1473
Query: 258 LKDYLAQIRTMESGLEAEKLQREVQEAQVNEEEVKGKIGKVKGEIDIQGQQSLRLENGIK 317
A+ E +A L R ++EA +EE++ +K E++ + +
Sbjct: 1474 -----AEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVH 1528
Query: 318 AVERSLGQATKRLQDKEQELEQLTKELR 345
+E+S ++++ + +LE+L EL+
Sbjct: 1529 ELEKSKRALETQMEEMKTQLEELEDELQ 1556
Score = 39.7 bits (91), Expect = 0.005
Identities = 46/237 (19%), Positives = 112/237 (47%), Gaps = 19/237 (8%)
Query: 119 SIKRREPKRKSLTFTGGAKGLMDIFGKGKETEFKQKVLNNCKTTADELKKLIRLQTEKLQ 178
+I+ + K+K F + L + GK+ F++++ N + ++ +L+ K
Sbjct: 1370 NIQLSDSKKKLQDFASTVEALEE----GKK-RFQKEIENLTQQYEEKAAAYDKLEKTK-N 1423
Query: 179 SIEKQLESNEIEIRFWEQKYNSNLEEEIVRLEQKIKR----NDVEIEEEEFWENELQIEQ 234
++++L+ +++ Q SNLE++ + +Q + + +E + E E + ++
Sbjct: 1424 RLQQELDDLVVDLDNQRQLV-SNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKE 1482
Query: 235 ENEKQLKDQLQEIRQKITECENKLKDYLAQIRTMES-----GLEAEKLQREVQEAQVNEE 289
L L+E + E E K A++ + S G +L++ + + E
Sbjct: 1483 TKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQME 1542
Query: 290 EVKGKIGKVKGEIDIQGQQSLRLENGIKAVERSLGQATKRLQDKEQELEQLTKELRQ 346
E+K ++ +++ E+ LRLE ++A++ GQ + LQ ++++ E+ ++L++
Sbjct: 1543 EMKTQLEELEDELQATEDAKLRLEVNMQALK---GQFERDLQARDEQNEEKRRQLQR 1596
Score = 37.4 bits (85), Expect = 0.024
Identities = 44/268 (16%), Positives = 119/268 (44%), Gaps = 12/268 (4%)
Query: 112 LRPQIDKSIKRREPKRKSLTFTGGAKGLMDIFGKGKETEFKQKVLNNCKTTADELKKLIR 171
L Q+++ + E L T AK +++ + + +F++ + + ++ ++L R
Sbjct: 1537 LETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQR 1596
Query: 172 LQTEKLQSIEKQLESNEIEIRFWEQKYNSNLEEEIVRLEQKIKRNDVEIEEEEFWENELQ 231
E +E + + + ++K +L++ ++ + IK + I++ + +++
Sbjct: 1597 QLHEYETELEDERKQRALAAAA-KKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMK 1655
Query: 232 IEQENEKQLKDQLQEIRQKITECENKLKDYLAQIRTMESGLEAEKLQREVQEAQVNEEEV 291
Q + + EI E E K K A + ++ L A + R+ +A + +EE+
Sbjct: 1656 DFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARK--QADLEKEEL 1713
Query: 292 KGKIGKVKGEIDIQGQQSLRLENGIKAVERSLGQATKRLQDKEQELEQLTKELRQVNLQQ 351
++ + G+ +L+ E + +E + Q + L++++ +E ++ +R+ Q
Sbjct: 1714 AEELAS-----SLSGRNALQDEK--RRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQ- 1765
Query: 352 FIQQTGTKVTVLPAEPIEIEASHADIER 379
+Q ++ + + E++ +ER
Sbjct: 1766 -AEQLSNELATERSTAQKNESARQQLER 1792
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 58.9 bits (141), Expect = 8e-09
Identities = 43/176 (24%), Positives = 90/176 (51%), Gaps = 5/176 (2%)
Query: 170 IRLQTEKLQSIEKQLESNEIEIRFWEQKYNSNLEEEIVRLEQKIKRNDVEIEEEEFWENE 229
++ + ++LQ +++ + E E++ EQK++ EE+ + EQ ++ E EE
Sbjct: 861 MQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRL 920
Query: 230 LQIEQENEK---QLKDQLQEIRQKITECENKLKDYLAQIRTMESGLEAEKLQREVQEAQV 286
+QE E+ +++ +L+E + + + + K Q+ +E LE E+ R Q+ Q+
Sbjct: 921 AAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAAR--QKLQL 978
Query: 287 NEEEVKGKIGKVKGEIDIQGQQSLRLENGIKAVERSLGQATKRLQDKEQELEQLTK 342
+ + KI K++ EI + Q+ +L K +E + T L ++E++ + LTK
Sbjct: 979 EKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTK 1034
Score = 51.6 bits (122), Expect = 1e-06
Identities = 60/246 (24%), Positives = 104/246 (42%), Gaps = 31/246 (12%)
Query: 109 LAKLRPQIDKSIKRREPKRKSLT------------FTGGAKGLMDIFGKGKETEFKQKVL 156
L L Q D +IK RE K L +IF KE E K K L
Sbjct: 1633 LKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSL 1692
Query: 157 NNCKTTADELKKLIRLQTEKLQSIEKQLESNEIEIRFWEQKYNSN-LEEEIVRLEQKIKR 215
AD ++ L + + LE E+ N L++E RLE +I +
Sbjct: 1693 E-----ADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQ 1747
Query: 216 NDVEIEEEEFWENELQIEQENEKQLKDQLQEIRQKITECENKLKDYLAQIRTMESGLEAE 275
+ E+EE EQ N + + D++++ Q+ + N+L + + ES +
Sbjct: 1748 LEEELEE----------EQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESA--RQ 1795
Query: 276 KLQREVQEAQVNEEEVKGKI-GKVKGEIDIQGQQSLRLENGIKAVERSLGQATKRLQDKE 334
+L+R+ +E + E++G + K K I + +LE ++ R ATK L+ K+
Sbjct: 1796 QLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKD 1855
Query: 335 QELEQL 340
++L+++
Sbjct: 1856 KKLKEI 1861
Score = 49.3 bits (116), Expect = 6e-06
Identities = 59/277 (21%), Positives = 130/277 (46%), Gaps = 27/277 (9%)
Query: 110 AKLRPQIDKSIKRREPKRKSLTFTGGAKGLMDIFGKGKETEFKQKVLNNCKTTAD-ELKK 168
A+L + D+ + + ++K A+ ++D+ + +E E ++ L K TA+ ++KK
Sbjct: 936 ARLEEEEDRGQQLQAERKKM------AQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKK 989
Query: 169 LIRLQTEKLQSIEKQLESNEIEIRFWEQKYNSNLEEEIVRLEQKIKRNDVEIEEEEFWEN 228
L +++ ++ Q E + E++ S+L + E+K K + E +
Sbjct: 990 L----EDEILVMDDQNNKLSKERKLLEERI-SDLTTNLAEEEEKAKNLTKLKNKHESMIS 1044
Query: 229 ELQIEQENEKQLKDQLQEIRQKITECENKLKDYLAQIRTMESGLEAEKLQREVQEAQVN- 287
EL++ + E++ + +L+++++K+ E D+ QI +++ + K+Q +E ++
Sbjct: 1045 ELEVRLKKEEKSRQELEKLKRKL---EGDASDFHEQIADLQAQIAELKMQLAKKEEELQA 1101
Query: 288 -----EEEVKGKIGKVKGEIDIQGQQSLRLENGIKAVERSLGQATKRLQDKEQELEQLTK 342
++E+ K +K +++G S L+ + + + +A K+ +D +ELE L
Sbjct: 1102 ALARLDDEIAQKNNALKKIRELEGHIS-DLQEDLDSERAARNKAEKQKRDLGEELEALKT 1160
Query: 343 ELRQ-----VNLQQFIQQTGTKVTVLPAEPIEIEASH 374
EL Q+ + +VTVL E SH
Sbjct: 1161 ELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSH 1197
Score = 45.4 bits (106), Expect = 9e-05
Identities = 41/213 (19%), Positives = 101/213 (47%), Gaps = 15/213 (7%)
Query: 146 GKETEFKQKVLNNCKTTADELKKLIRLQTEKLQSIEKQLESNEIEIRFWEQKYNSNLEEE 205
GK +K +T +E+K + ++LQ+ E E+ ++ + ++ +L+
Sbjct: 1531 GKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQAR 1590
Query: 206 IVRLEQKIKRNDVEIEEEEFWENELQIEQEN-------EKQLKDQLQEIRQKITECENKL 258
+ E+K ++ ++ E +E EL+ E++ +K+L+ L+++ +
Sbjct: 1591 DEQNEEKRRQLQRQLHE---YETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGR 1647
Query: 259 KDYLAQIRTMESGLEAEKLQREVQEAQVNEEEVKGKIGKVKGEIDIQGQQSLRLENGIKA 318
++ + Q+R +++ + + QRE+++A+ + +E+ + + + ++L+ + A
Sbjct: 1648 EEAIKQLRKLQA--QMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAA 1705
Query: 319 VERSLGQATKRLQDKEQELEQLTKELRQVNLQQ 351
ER+ QA +KE+ E+L L N Q
Sbjct: 1706 AERARKQAD---LEKEELAEELASSLSGRNALQ 1735
Score = 44.7 bits (104), Expect = 1e-04
Identities = 48/199 (24%), Positives = 93/199 (46%), Gaps = 33/199 (16%)
Query: 178 QSIEKQLESNEIEIRFWEQKYNSNLEEEIVRLEQKIKRNDVEIEEEEFWENELQIEQENE 237
++++++ S+E +++ QK+ +EE +LEQ KR +++ N+ +E+EN
Sbjct: 1188 KALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQ-FKRAKANLDK-----NKQTLEKENA 1241
Query: 238 KQLKDQLQEIRQKITECENKLKDYLAQIRTMESGL------------EAEKLQREVQEAQ 285
L +L+ + Q E E+K K AQ++ ++S + KLQ EV+
Sbjct: 1242 -DLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVT 1300
Query: 286 VNEEEVKGKIGKVKGEI--------DIQG--QQSLRLENGIKAVERSLGQATKRLQDK-E 334
E +GK K+ ++ D Q Q+ R + + R L + LQD+ +
Sbjct: 1301 GMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLD 1360
Query: 335 QELE---QLTKELRQVNLQ 350
+E+E L + + +N+Q
Sbjct: 1361 EEMEAKQNLERHISTLNIQ 1379
Score = 42.4 bits (98), Expect = 7e-04
Identities = 43/161 (26%), Positives = 78/161 (48%), Gaps = 24/161 (14%)
Query: 234 QENEKQLK-DQLQEIRQKITECENKLKDYLAQIR---TMESGLEAEKLQREVQEAQVNEE 289
QE E Q K D+LQ+ +++ + EN+LK+ L Q T E L E+LQ E E E
Sbjct: 857 QEEEMQAKEDELQKTKERQQKAENELKE-LEQKHSQLTEEKNLLQEQLQAET-ELYAEAE 914
Query: 290 EVKGKIGKVKGEI-DIQGQQSLRLENGIKAVERSLGQATKRLQDKEQELEQLTKELRQ-- 346
E++ ++ K E+ +I + RLE +D+ Q+L+ K++ Q
Sbjct: 915 EMRVRLAAKKQELEEILHEMEARLEEE---------------EDRGQQLQAERKKMAQQM 959
Query: 347 VNLQQFIQQTGTKVTVLPAEPIEIEASHADIERGIIILSDK 387
++L++ +++ L E + EA +E I+++ D+
Sbjct: 960 LDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQ 1000
Score = 42.4 bits (98), Expect = 7e-04
Identities = 41/177 (23%), Positives = 77/177 (43%), Gaps = 23/177 (12%)
Query: 171 RLQTEKLQSIEKQLESNEIEIRF----WEQKYNSNLEEEIVRLEQKIKRNDVEIEEEEFW 226
R +K +S +QLE E+R E S + I LE KI + + ++E+E
Sbjct: 1784 RSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEARE 1843
Query: 227 EN--------------ELQIEQENEKQLKDQLQEIRQKITECENKLKDYLAQIRTMESGL 272
+ E+ ++ E+E+++ +Q +E +K +LK L + +
Sbjct: 1844 KQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRI 1903
Query: 273 EA--EKLQREVQEAQVNEEEVKGKIGKVKGEIDIQGQQSL---RLENGIKAVERSLG 324
A KLQRE+ EA + E + ++ +K ++ + S R G + +E + G
Sbjct: 1904 NANRRKLQRELDEATESNEAMGREVNALKSKLRRGNETSFVPSRRSGGRRVIENADG 1960
Score = 41.6 bits (96), Expect = 0.001
Identities = 41/204 (20%), Positives = 91/204 (44%), Gaps = 30/204 (14%)
Query: 148 ETEFKQKVLNNCKTTADELKKLIRLQTEKLQSIEKQLESNEIEIRFWEQKYNSNLEEEIV 207
E E +LN + A +L K + + +LQ ++ L+ E + N+ ++
Sbjct: 1295 EVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQE--------ETRQKLNVSTKLR 1346
Query: 208 RLEQKIKRNDVEIEEEEFWENELQIEQENEKQLKDQLQEIRQKITECENKLKDYLAQIRT 267
+LE EE +++L E E ++ L+ + + ++++ + KL+D+ + +
Sbjct: 1347 QLE----------EERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEA 1396
Query: 268 MESGLEAEKLQREVQEAQVNEEE---VKGKIGKVKGEIDIQGQQSLRLENGIKAVERSLG 324
+E G ++ Q+E++ EE K+ K K + QQ L + + +
Sbjct: 1397 LEEG--KKRFQKEIENLTQQYEEKAAAYDKLEKTKNRL----QQEL---DDLVVDLDNQR 1447
Query: 325 QATKRLQDKEQELEQLTKELRQVN 348
Q L+ K+++ +QL E + ++
Sbjct: 1448 QLVSNLEKKQRKFDQLLAEEKNIS 1471
Score = 40.8 bits (94), Expect = 0.002
Identities = 38/195 (19%), Positives = 88/195 (45%), Gaps = 33/195 (16%)
Query: 153 QKVLNNCKTTADELKKLIRLQTEKLQSIEKQLESNEIEIRFWEQKYNSNLEEEIVRLEQK 212
Q+ L++ + ++ +K R E+L++++ +LE ++ +Q+ + E+E+ L++
Sbjct: 1131 QEDLDSERAARNKAEKQKRDLGEELEALKTELEDT-LDSTATQQELRAKREQEVTVLKKA 1189
Query: 213 IKRNDVEIEEEEFWENELQIEQENEKQLKDQLQEIRQKITECENKLKDYLAQIRTMESGL 272
+ +EE +E Q+ QE+RQK + +L + L Q + ++ L
Sbjct: 1190 L--------DEETRSHEAQV------------QEMRQKHAQAVEELTEQLEQFKRAKANL 1229
Query: 273 EAEKLQREVQEAQVNEEEVKGKIGKVKGEIDIQGQQSLRLENGIKAVERSLGQATKRLQD 332
+ K E + A + GE+ + GQ +E+ K +E + + + D
Sbjct: 1230 DKNKQTLEKENAD------------LAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSD 1277
Query: 333 KEQELEQLTKELRQV 347
E+ +L ++ ++
Sbjct: 1278 GERARAELNDKVHKL 1292
Score = 40.8 bits (94), Expect = 0.002
Identities = 43/208 (20%), Positives = 95/208 (45%), Gaps = 14/208 (6%)
Query: 147 KETEFKQKVLNNCKTTADEL---KKLIRLQTEKLQSIEKQLESNEIEIRFWEQKYNSN-- 201
+E E KQ + + T +L KK ++ ++++E+ + + EI Q+Y
Sbjct: 1361 EEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAA 1420
Query: 202 ----LEEEIVRLEQKIKRNDVEIEEEEFWENELQIEQENEKQLKDQLQEIRQKITECENK 257
LE+ RL+Q++ V+++ + + L+ +Q QL + + I K + ++
Sbjct: 1421 AYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDR 1480
Query: 258 LKDYLAQIRTMESGLEAEKLQREVQEAQVNEEEVKGKIGKVKGEIDIQGQQSLRLENGIK 317
A+ E +A L R ++EA +EE++ +K E++ + +
Sbjct: 1481 -----AEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVH 1535
Query: 318 AVERSLGQATKRLQDKEQELEQLTKELR 345
+E+S ++++ + +LE+L EL+
Sbjct: 1536 ELEKSKRALETQMEEMKTQLEELEDELQ 1563
Score = 39.7 bits (91), Expect = 0.005
Identities = 46/237 (19%), Positives = 112/237 (47%), Gaps = 19/237 (8%)
Query: 119 SIKRREPKRKSLTFTGGAKGLMDIFGKGKETEFKQKVLNNCKTTADELKKLIRLQTEKLQ 178
+I+ + K+K F + L + GK+ F++++ N + ++ +L+ K
Sbjct: 1377 NIQLSDSKKKLQDFASTVEALEE----GKK-RFQKEIENLTQQYEEKAAAYDKLEKTK-N 1430
Query: 179 SIEKQLESNEIEIRFWEQKYNSNLEEEIVRLEQKIKR----NDVEIEEEEFWENELQIEQ 234
++++L+ +++ Q SNLE++ + +Q + + +E + E E + ++
Sbjct: 1431 RLQQELDDLVVDLDNQRQLV-SNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKE 1489
Query: 235 ENEKQLKDQLQEIRQKITECENKLKDYLAQIRTMES-----GLEAEKLQREVQEAQVNEE 289
L L+E + E E K A++ + S G +L++ + + E
Sbjct: 1490 TKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQME 1549
Query: 290 EVKGKIGKVKGEIDIQGQQSLRLENGIKAVERSLGQATKRLQDKEQELEQLTKELRQ 346
E+K ++ +++ E+ LRLE ++A++ GQ + LQ ++++ E+ ++L++
Sbjct: 1550 EMKTQLEELEDELQATEDAKLRLEVNMQALK---GQFERDLQARDEQNEEKRRQLQR 1603
Score = 37.4 bits (85), Expect = 0.024
Identities = 44/268 (16%), Positives = 119/268 (44%), Gaps = 12/268 (4%)
Query: 112 LRPQIDKSIKRREPKRKSLTFTGGAKGLMDIFGKGKETEFKQKVLNNCKTTADELKKLIR 171
L Q+++ + E L T AK +++ + + +F++ + + ++ ++L R
Sbjct: 1544 LETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQR 1603
Query: 172 LQTEKLQSIEKQLESNEIEIRFWEQKYNSNLEEEIVRLEQKIKRNDVEIEEEEFWENELQ 231
E +E + + + ++K +L++ ++ + IK + I++ + +++
Sbjct: 1604 QLHEYETELEDERKQRALAAAA-KKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMK 1662
Query: 232 IEQENEKQLKDQLQEIRQKITECENKLKDYLAQIRTMESGLEAEKLQREVQEAQVNEEEV 291
Q + + EI E E K K A + ++ L A + R+ +A + +EE+
Sbjct: 1663 DFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARK--QADLEKEEL 1720
Query: 292 KGKIGKVKGEIDIQGQQSLRLENGIKAVERSLGQATKRLQDKEQELEQLTKELRQVNLQQ 351
++ + G+ +L+ E + +E + Q + L++++ +E ++ +R+ Q
Sbjct: 1721 AEELAS-----SLSGRNALQDEK--RRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQ- 1772
Query: 352 FIQQTGTKVTVLPAEPIEIEASHADIER 379
+Q ++ + + E++ +ER
Sbjct: 1773 -AEQLSNELATERSTAQKNESARQQLER 1799
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 58.9 bits (141), Expect = 8e-09
Identities = 43/176 (24%), Positives = 90/176 (51%), Gaps = 5/176 (2%)
Query: 170 IRLQTEKLQSIEKQLESNEIEIRFWEQKYNSNLEEEIVRLEQKIKRNDVEIEEEEFWENE 229
++ + ++LQ +++ + E E++ EQK++ EE+ + EQ ++ E EE
Sbjct: 861 MQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRL 920
Query: 230 LQIEQENEK---QLKDQLQEIRQKITECENKLKDYLAQIRTMESGLEAEKLQREVQEAQV 286
+QE E+ +++ +L+E + + + + K Q+ +E LE E+ R Q+ Q+
Sbjct: 921 AAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAAR--QKLQL 978
Query: 287 NEEEVKGKIGKVKGEIDIQGQQSLRLENGIKAVERSLGQATKRLQDKEQELEQLTK 342
+ + KI K++ EI + Q+ +L K +E + T L ++E++ + LTK
Sbjct: 979 EKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTK 1034
Score = 51.6 bits (122), Expect = 1e-06
Identities = 60/246 (24%), Positives = 104/246 (42%), Gaps = 31/246 (12%)
Query: 109 LAKLRPQIDKSIKRREPKRKSLT------------FTGGAKGLMDIFGKGKETEFKQKVL 156
L L Q D +IK RE K L +IF KE E K K L
Sbjct: 1633 LKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSL 1692
Query: 157 NNCKTTADELKKLIRLQTEKLQSIEKQLESNEIEIRFWEQKYNSN-LEEEIVRLEQKIKR 215
AD ++ L + + LE E+ N L++E RLE +I +
Sbjct: 1693 E-----ADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQ 1747
Query: 216 NDVEIEEEEFWENELQIEQENEKQLKDQLQEIRQKITECENKLKDYLAQIRTMESGLEAE 275
+ E+EE EQ N + + D++++ Q+ + N+L + + ES +
Sbjct: 1748 LEEELEE----------EQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESA--RQ 1795
Query: 276 KLQREVQEAQVNEEEVKGKI-GKVKGEIDIQGQQSLRLENGIKAVERSLGQATKRLQDKE 334
+L+R+ +E + E++G + K K I + +LE ++ R ATK L+ K+
Sbjct: 1796 QLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKD 1855
Query: 335 QELEQL 340
++L+++
Sbjct: 1856 KKLKEI 1861
Score = 49.3 bits (116), Expect = 6e-06
Identities = 59/277 (21%), Positives = 130/277 (46%), Gaps = 27/277 (9%)
Query: 110 AKLRPQIDKSIKRREPKRKSLTFTGGAKGLMDIFGKGKETEFKQKVLNNCKTTAD-ELKK 168
A+L + D+ + + ++K A+ ++D+ + +E E ++ L K TA+ ++KK
Sbjct: 936 ARLEEEEDRGQQLQAERKKM------AQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKK 989
Query: 169 LIRLQTEKLQSIEKQLESNEIEIRFWEQKYNSNLEEEIVRLEQKIKRNDVEIEEEEFWEN 228
L +++ ++ Q E + E++ S+L + E+K K + E +
Sbjct: 990 L----EDEILVMDDQNNKLSKERKLLEERI-SDLTTNLAEEEEKAKNLTKLKNKHESMIS 1044
Query: 229 ELQIEQENEKQLKDQLQEIRQKITECENKLKDYLAQIRTMESGLEAEKLQREVQEAQVN- 287
EL++ + E++ + +L+++++K+ E D+ QI +++ + K+Q +E ++
Sbjct: 1045 ELEVRLKKEEKSRQELEKLKRKL---EGDASDFHEQIADLQAQIAELKMQLAKKEEELQA 1101
Query: 288 -----EEEVKGKIGKVKGEIDIQGQQSLRLENGIKAVERSLGQATKRLQDKEQELEQLTK 342
++E+ K +K +++G S L+ + + + +A K+ +D +ELE L
Sbjct: 1102 ALARLDDEIAQKNNALKKIRELEGHIS-DLQEDLDSERAARNKAEKQKRDLGEELEALKT 1160
Query: 343 ELRQ-----VNLQQFIQQTGTKVTVLPAEPIEIEASH 374
EL Q+ + +VTVL E SH
Sbjct: 1161 ELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSH 1197
Score = 45.4 bits (106), Expect = 9e-05
Identities = 41/213 (19%), Positives = 101/213 (47%), Gaps = 15/213 (7%)
Query: 146 GKETEFKQKVLNNCKTTADELKKLIRLQTEKLQSIEKQLESNEIEIRFWEQKYNSNLEEE 205
GK +K +T +E+K + ++LQ+ E E+ ++ + ++ +L+
Sbjct: 1531 GKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQAR 1590
Query: 206 IVRLEQKIKRNDVEIEEEEFWENELQIEQEN-------EKQLKDQLQEIRQKITECENKL 258
+ E+K ++ ++ E +E EL+ E++ +K+L+ L+++ +
Sbjct: 1591 DEQNEEKRRQLQRQLHE---YETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGR 1647
Query: 259 KDYLAQIRTMESGLEAEKLQREVQEAQVNEEEVKGKIGKVKGEIDIQGQQSLRLENGIKA 318
++ + Q+R +++ + + QRE+++A+ + +E+ + + + ++L+ + A
Sbjct: 1648 EEAIKQLRKLQA--QMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAA 1705
Query: 319 VERSLGQATKRLQDKEQELEQLTKELRQVNLQQ 351
ER+ QA +KE+ E+L L N Q
Sbjct: 1706 AERARKQAD---LEKEELAEELASSLSGRNALQ 1735
Score = 44.7 bits (104), Expect = 1e-04
Identities = 48/199 (24%), Positives = 93/199 (46%), Gaps = 33/199 (16%)
Query: 178 QSIEKQLESNEIEIRFWEQKYNSNLEEEIVRLEQKIKRNDVEIEEEEFWENELQIEQENE 237
++++++ S+E +++ QK+ +EE +LEQ KR +++ N+ +E+EN
Sbjct: 1188 KALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQ-FKRAKANLDK-----NKQTLEKENA 1241
Query: 238 KQLKDQLQEIRQKITECENKLKDYLAQIRTMESGL------------EAEKLQREVQEAQ 285
L +L+ + Q E E+K K AQ++ ++S + KLQ EV+
Sbjct: 1242 -DLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVT 1300
Query: 286 VNEEEVKGKIGKVKGEI--------DIQG--QQSLRLENGIKAVERSLGQATKRLQDK-E 334
E +GK K+ ++ D Q Q+ R + + R L + LQD+ +
Sbjct: 1301 GMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLD 1360
Query: 335 QELE---QLTKELRQVNLQ 350
+E+E L + + +N+Q
Sbjct: 1361 EEMEAKQNLERHISTLNIQ 1379
Score = 44.3 bits (103), Expect = 2e-04
Identities = 35/157 (22%), Positives = 72/157 (45%), Gaps = 9/157 (5%)
Query: 171 RLQTEKLQSIEKQLESNEIEIRF----WEQKYNSNLEEEIVRLEQKIKRNDVEIEEEEFW 226
R +K +S +QLE E+R E S + I LE KI + + ++E+E
Sbjct: 1784 RSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEA-- 1841
Query: 227 ENELQIEQENEKQLKDQLQEIRQKITECENKLKDYLAQIRTMESGLEAEKLQREVQEAQV 286
E Q ++ KQ +L+EI ++ + + Y Q + ++L+R+++EA+
Sbjct: 1842 -REKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAE--KGNARVKQLKRQLEEAEE 1898
Query: 287 NEEEVKGKIGKVKGEIDIQGQQSLRLENGIKAVERSL 323
+ + K++ E+D + + + + A++ L
Sbjct: 1899 ESQRINANRRKLQRELDEATESNEAMGREVNALKSKL 1935
Score = 42.4 bits (98), Expect = 7e-04
Identities = 43/161 (26%), Positives = 78/161 (48%), Gaps = 24/161 (14%)
Query: 234 QENEKQLK-DQLQEIRQKITECENKLKDYLAQIR---TMESGLEAEKLQREVQEAQVNEE 289
QE E Q K D+LQ+ +++ + EN+LK+ L Q T E L E+LQ E E E
Sbjct: 857 QEEEMQAKEDELQKTKERQQKAENELKE-LEQKHSQLTEEKNLLQEQLQAET-ELYAEAE 914
Query: 290 EVKGKIGKVKGEI-DIQGQQSLRLENGIKAVERSLGQATKRLQDKEQELEQLTKELRQ-- 346
E++ ++ K E+ +I + RLE +D+ Q+L+ K++ Q
Sbjct: 915 EMRVRLAAKKQELEEILHEMEARLEEE---------------EDRGQQLQAERKKMAQQM 959
Query: 347 VNLQQFIQQTGTKVTVLPAEPIEIEASHADIERGIIILSDK 387
++L++ +++ L E + EA +E I+++ D+
Sbjct: 960 LDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQ 1000
Score = 41.6 bits (96), Expect = 0.001
Identities = 41/204 (20%), Positives = 91/204 (44%), Gaps = 30/204 (14%)
Query: 148 ETEFKQKVLNNCKTTADELKKLIRLQTEKLQSIEKQLESNEIEIRFWEQKYNSNLEEEIV 207
E E +LN + A +L K + + +LQ ++ L+ E + N+ ++
Sbjct: 1295 EVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQE--------ETRQKLNVSTKLR 1346
Query: 208 RLEQKIKRNDVEIEEEEFWENELQIEQENEKQLKDQLQEIRQKITECENKLKDYLAQIRT 267
+LE EE +++L E E ++ L+ + + ++++ + KL+D+ + +
Sbjct: 1347 QLE----------EERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEA 1396
Query: 268 MESGLEAEKLQREVQEAQVNEEE---VKGKIGKVKGEIDIQGQQSLRLENGIKAVERSLG 324
+E G ++ Q+E++ EE K+ K K + QQ L + + +
Sbjct: 1397 LEEG--KKRFQKEIENLTQQYEEKAAAYDKLEKTKNRL----QQEL---DDLVVDLDNQR 1447
Query: 325 QATKRLQDKEQELEQLTKELRQVN 348
Q L+ K+++ +QL E + ++
Sbjct: 1448 QLVSNLEKKQRKFDQLLAEEKNIS 1471
Score = 40.8 bits (94), Expect = 0.002
Identities = 38/195 (19%), Positives = 88/195 (45%), Gaps = 33/195 (16%)
Query: 153 QKVLNNCKTTADELKKLIRLQTEKLQSIEKQLESNEIEIRFWEQKYNSNLEEEIVRLEQK 212
Q+ L++ + ++ +K R E+L++++ +LE ++ +Q+ + E+E+ L++
Sbjct: 1131 QEDLDSERAARNKAEKQKRDLGEELEALKTELEDT-LDSTATQQELRAKREQEVTVLKKA 1189
Query: 213 IKRNDVEIEEEEFWENELQIEQENEKQLKDQLQEIRQKITECENKLKDYLAQIRTMESGL 272
+ +EE +E Q+ QE+RQK + +L + L Q + ++ L
Sbjct: 1190 L--------DEETRSHEAQV------------QEMRQKHAQAVEELTEQLEQFKRAKANL 1229
Query: 273 EAEKLQREVQEAQVNEEEVKGKIGKVKGEIDIQGQQSLRLENGIKAVERSLGQATKRLQD 332
+ K E + A + GE+ + GQ +E+ K +E + + + D
Sbjct: 1230 DKNKQTLEKENAD------------LAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSD 1277
Query: 333 KEQELEQLTKELRQV 347
E+ +L ++ ++
Sbjct: 1278 GERARAELNDKVHKL 1292
Score = 40.8 bits (94), Expect = 0.002
Identities = 43/208 (20%), Positives = 95/208 (45%), Gaps = 14/208 (6%)
Query: 147 KETEFKQKVLNNCKTTADEL---KKLIRLQTEKLQSIEKQLESNEIEIRFWEQKYNSN-- 201
+E E KQ + + T +L KK ++ ++++E+ + + EI Q+Y
Sbjct: 1361 EEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAA 1420
Query: 202 ----LEEEIVRLEQKIKRNDVEIEEEEFWENELQIEQENEKQLKDQLQEIRQKITECENK 257
LE+ RL+Q++ V+++ + + L+ +Q QL + + I K + ++
Sbjct: 1421 AYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDR 1480
Query: 258 LKDYLAQIRTMESGLEAEKLQREVQEAQVNEEEVKGKIGKVKGEIDIQGQQSLRLENGIK 317
A+ E +A L R ++EA +EE++ +K E++ + +
Sbjct: 1481 -----AEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVH 1535
Query: 318 AVERSLGQATKRLQDKEQELEQLTKELR 345
+E+S ++++ + +LE+L EL+
Sbjct: 1536 ELEKSKRALETQMEEMKTQLEELEDELQ 1563
Score = 39.7 bits (91), Expect = 0.005
Identities = 46/237 (19%), Positives = 112/237 (47%), Gaps = 19/237 (8%)
Query: 119 SIKRREPKRKSLTFTGGAKGLMDIFGKGKETEFKQKVLNNCKTTADELKKLIRLQTEKLQ 178
+I+ + K+K F + L + GK+ F++++ N + ++ +L+ K
Sbjct: 1377 NIQLSDSKKKLQDFASTVEALEE----GKK-RFQKEIENLTQQYEEKAAAYDKLEKTK-N 1430
Query: 179 SIEKQLESNEIEIRFWEQKYNSNLEEEIVRLEQKIKR----NDVEIEEEEFWENELQIEQ 234
++++L+ +++ Q SNLE++ + +Q + + +E + E E + ++
Sbjct: 1431 RLQQELDDLVVDLDNQRQLV-SNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKE 1489
Query: 235 ENEKQLKDQLQEIRQKITECENKLKDYLAQIRTMES-----GLEAEKLQREVQEAQVNEE 289
L L+E + E E K A++ + S G +L++ + + E
Sbjct: 1490 TKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQME 1549
Query: 290 EVKGKIGKVKGEIDIQGQQSLRLENGIKAVERSLGQATKRLQDKEQELEQLTKELRQ 346
E+K ++ +++ E+ LRLE ++A++ GQ + LQ ++++ E+ ++L++
Sbjct: 1550 EMKTQLEELEDELQATEDAKLRLEVNMQALK---GQFERDLQARDEQNEEKRRQLQR 1603
Score = 37.4 bits (85), Expect = 0.024
Identities = 44/268 (16%), Positives = 119/268 (44%), Gaps = 12/268 (4%)
Query: 112 LRPQIDKSIKRREPKRKSLTFTGGAKGLMDIFGKGKETEFKQKVLNNCKTTADELKKLIR 171
L Q+++ + E L T AK +++ + + +F++ + + ++ ++L R
Sbjct: 1544 LETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQR 1603
Query: 172 LQTEKLQSIEKQLESNEIEIRFWEQKYNSNLEEEIVRLEQKIKRNDVEIEEEEFWENELQ 231
E +E + + + ++K +L++ ++ + IK + I++ + +++
Sbjct: 1604 QLHEYETELEDERKQRALAAAA-KKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMK 1662
Query: 232 IEQENEKQLKDQLQEIRQKITECENKLKDYLAQIRTMESGLEAEKLQREVQEAQVNEEEV 291
Q + + EI E E K K A + ++ L A + R+ +A + +EE+
Sbjct: 1663 DFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARK--QADLEKEEL 1720
Query: 292 KGKIGKVKGEIDIQGQQSLRLENGIKAVERSLGQATKRLQDKEQELEQLTKELRQVNLQQ 351
++ + G+ +L+ E + +E + Q + L++++ +E ++ +R+ Q
Sbjct: 1721 AEELAS-----SLSGRNALQDEK--RRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQ- 1772
Query: 352 FIQQTGTKVTVLPAEPIEIEASHADIER 379
+Q ++ + + E++ +ER
Sbjct: 1773 -AEQLSNELATERSTAQKNESARQQLER 1799
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 58.9 bits (141), Expect = 8e-09
Identities = 43/176 (24%), Positives = 90/176 (51%), Gaps = 5/176 (2%)
Query: 170 IRLQTEKLQSIEKQLESNEIEIRFWEQKYNSNLEEEIVRLEQKIKRNDVEIEEEEFWENE 229
++ + ++LQ +++ + E E++ EQK++ EE+ + EQ ++ E EE
Sbjct: 854 MQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRL 913
Query: 230 LQIEQENEK---QLKDQLQEIRQKITECENKLKDYLAQIRTMESGLEAEKLQREVQEAQV 286
+QE E+ +++ +L+E + + + + K Q+ +E LE E+ R Q+ Q+
Sbjct: 914 AAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAAR--QKLQL 971
Query: 287 NEEEVKGKIGKVKGEIDIQGQQSLRLENGIKAVERSLGQATKRLQDKEQELEQLTK 342
+ + KI K++ EI + Q+ +L K +E + T L ++E++ + LTK
Sbjct: 972 EKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTK 1027
Score = 51.6 bits (122), Expect = 1e-06
Identities = 60/246 (24%), Positives = 104/246 (42%), Gaps = 31/246 (12%)
Query: 109 LAKLRPQIDKSIKRREPKRKSLT------------FTGGAKGLMDIFGKGKETEFKQKVL 156
L L Q D +IK RE K L +IF KE E K K L
Sbjct: 1626 LKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSL 1685
Query: 157 NNCKTTADELKKLIRLQTEKLQSIEKQLESNEIEIRFWEQKYNSN-LEEEIVRLEQKIKR 215
AD ++ L + + LE E+ N L++E RLE +I +
Sbjct: 1686 E-----ADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQ 1740
Query: 216 NDVEIEEEEFWENELQIEQENEKQLKDQLQEIRQKITECENKLKDYLAQIRTMESGLEAE 275
+ E+EE EQ N + + D++++ Q+ + N+L + + ES +
Sbjct: 1741 LEEELEE----------EQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESA--RQ 1788
Query: 276 KLQREVQEAQVNEEEVKGKI-GKVKGEIDIQGQQSLRLENGIKAVERSLGQATKRLQDKE 334
+L+R+ +E + E++G + K K I + +LE ++ R ATK L+ K+
Sbjct: 1789 QLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKD 1848
Query: 335 QELEQL 340
++L+++
Sbjct: 1849 KKLKEI 1854
Score = 49.3 bits (116), Expect = 6e-06
Identities = 59/277 (21%), Positives = 130/277 (46%), Gaps = 27/277 (9%)
Query: 110 AKLRPQIDKSIKRREPKRKSLTFTGGAKGLMDIFGKGKETEFKQKVLNNCKTTAD-ELKK 168
A+L + D+ + + ++K A+ ++D+ + +E E ++ L K TA+ ++KK
Sbjct: 929 ARLEEEEDRGQQLQAERKKM------AQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKK 982
Query: 169 LIRLQTEKLQSIEKQLESNEIEIRFWEQKYNSNLEEEIVRLEQKIKRNDVEIEEEEFWEN 228
L +++ ++ Q E + E++ S+L + E+K K + E +
Sbjct: 983 L----EDEILVMDDQNNKLSKERKLLEERI-SDLTTNLAEEEEKAKNLTKLKNKHESMIS 1037
Query: 229 ELQIEQENEKQLKDQLQEIRQKITECENKLKDYLAQIRTMESGLEAEKLQREVQEAQVN- 287
EL++ + E++ + +L+++++K+ E D+ QI +++ + K+Q +E ++
Sbjct: 1038 ELEVRLKKEEKSRQELEKLKRKL---EGDASDFHEQIADLQAQIAELKMQLAKKEEELQA 1094
Query: 288 -----EEEVKGKIGKVKGEIDIQGQQSLRLENGIKAVERSLGQATKRLQDKEQELEQLTK 342
++E+ K +K +++G S L+ + + + +A K+ +D +ELE L
Sbjct: 1095 ALARLDDEIAQKNNALKKIRELEGHIS-DLQEDLDSERAARNKAEKQKRDLGEELEALKT 1153
Query: 343 ELRQ-----VNLQQFIQQTGTKVTVLPAEPIEIEASH 374
EL Q+ + +VTVL E SH
Sbjct: 1154 ELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSH 1190
Score = 45.4 bits (106), Expect = 9e-05
Identities = 41/213 (19%), Positives = 101/213 (47%), Gaps = 15/213 (7%)
Query: 146 GKETEFKQKVLNNCKTTADELKKLIRLQTEKLQSIEKQLESNEIEIRFWEQKYNSNLEEE 205
GK +K +T +E+K + ++LQ+ E E+ ++ + ++ +L+
Sbjct: 1524 GKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQAR 1583
Query: 206 IVRLEQKIKRNDVEIEEEEFWENELQIEQEN-------EKQLKDQLQEIRQKITECENKL 258
+ E+K ++ ++ E +E EL+ E++ +K+L+ L+++ +
Sbjct: 1584 DEQNEEKRRQLQRQLHE---YETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGR 1640
Query: 259 KDYLAQIRTMESGLEAEKLQREVQEAQVNEEEVKGKIGKVKGEIDIQGQQSLRLENGIKA 318
++ + Q+R +++ + + QRE+++A+ + +E+ + + + ++L+ + A
Sbjct: 1641 EEAIKQLRKLQA--QMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAA 1698
Query: 319 VERSLGQATKRLQDKEQELEQLTKELRQVNLQQ 351
ER+ QA +KE+ E+L L N Q
Sbjct: 1699 AERARKQAD---LEKEELAEELASSLSGRNALQ 1728
Score = 44.7 bits (104), Expect = 1e-04
Identities = 48/199 (24%), Positives = 93/199 (46%), Gaps = 33/199 (16%)
Query: 178 QSIEKQLESNEIEIRFWEQKYNSNLEEEIVRLEQKIKRNDVEIEEEEFWENELQIEQENE 237
++++++ S+E +++ QK+ +EE +LEQ KR +++ N+ +E+EN
Sbjct: 1181 KALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQ-FKRAKANLDK-----NKQTLEKENA 1234
Query: 238 KQLKDQLQEIRQKITECENKLKDYLAQIRTMESGL------------EAEKLQREVQEAQ 285
L +L+ + Q E E+K K AQ++ ++S + KLQ EV+
Sbjct: 1235 -DLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVT 1293
Query: 286 VNEEEVKGKIGKVKGEI--------DIQG--QQSLRLENGIKAVERSLGQATKRLQDK-E 334
E +GK K+ ++ D Q Q+ R + + R L + LQD+ +
Sbjct: 1294 GMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLD 1353
Query: 335 QELE---QLTKELRQVNLQ 350
+E+E L + + +N+Q
Sbjct: 1354 EEMEAKQNLERHISTLNIQ 1372
Score = 44.3 bits (103), Expect = 2e-04
Identities = 35/157 (22%), Positives = 72/157 (45%), Gaps = 9/157 (5%)
Query: 171 RLQTEKLQSIEKQLESNEIEIRF----WEQKYNSNLEEEIVRLEQKIKRNDVEIEEEEFW 226
R +K +S +QLE E+R E S + I LE KI + + ++E+E
Sbjct: 1777 RSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEA-- 1834
Query: 227 ENELQIEQENEKQLKDQLQEIRQKITECENKLKDYLAQIRTMESGLEAEKLQREVQEAQV 286
E Q ++ KQ +L+EI ++ + + Y Q + ++L+R+++EA+
Sbjct: 1835 -REKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAE--KGNARVKQLKRQLEEAEE 1891
Query: 287 NEEEVKGKIGKVKGEIDIQGQQSLRLENGIKAVERSL 323
+ + K++ E+D + + + + A++ L
Sbjct: 1892 ESQRINANRRKLQRELDEATESNEAMGREVNALKSKL 1928
Score = 42.4 bits (98), Expect = 7e-04
Identities = 43/161 (26%), Positives = 78/161 (48%), Gaps = 24/161 (14%)
Query: 234 QENEKQLK-DQLQEIRQKITECENKLKDYLAQIR---TMESGLEAEKLQREVQEAQVNEE 289
QE E Q K D+LQ+ +++ + EN+LK+ L Q T E L E+LQ E E E
Sbjct: 850 QEEEMQAKEDELQKTKERQQKAENELKE-LEQKHSQLTEEKNLLQEQLQAET-ELYAEAE 907
Query: 290 EVKGKIGKVKGEI-DIQGQQSLRLENGIKAVERSLGQATKRLQDKEQELEQLTKELRQ-- 346
E++ ++ K E+ +I + RLE +D+ Q+L+ K++ Q
Sbjct: 908 EMRVRLAAKKQELEEILHEMEARLEEE---------------EDRGQQLQAERKKMAQQM 952
Query: 347 VNLQQFIQQTGTKVTVLPAEPIEIEASHADIERGIIILSDK 387
++L++ +++ L E + EA +E I+++ D+
Sbjct: 953 LDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQ 993
Score = 41.6 bits (96), Expect = 0.001
Identities = 41/204 (20%), Positives = 91/204 (44%), Gaps = 30/204 (14%)
Query: 148 ETEFKQKVLNNCKTTADELKKLIRLQTEKLQSIEKQLESNEIEIRFWEQKYNSNLEEEIV 207
E E +LN + A +L K + + +LQ ++ L+ E + N+ ++
Sbjct: 1288 EVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQE--------ETRQKLNVSTKLR 1339
Query: 208 RLEQKIKRNDVEIEEEEFWENELQIEQENEKQLKDQLQEIRQKITECENKLKDYLAQIRT 267
+LE EE +++L E E ++ L+ + + ++++ + KL+D+ + +
Sbjct: 1340 QLE----------EERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEA 1389
Query: 268 MESGLEAEKLQREVQEAQVNEEE---VKGKIGKVKGEIDIQGQQSLRLENGIKAVERSLG 324
+E G ++ Q+E++ EE K+ K K + QQ L + + +
Sbjct: 1390 LEEG--KKRFQKEIENLTQQYEEKAAAYDKLEKTKNRL----QQEL---DDLVVDLDNQR 1440
Query: 325 QATKRLQDKEQELEQLTKELRQVN 348
Q L+ K+++ +QL E + ++
Sbjct: 1441 QLVSNLEKKQRKFDQLLAEEKNIS 1464
Score = 40.8 bits (94), Expect = 0.002
Identities = 38/195 (19%), Positives = 88/195 (45%), Gaps = 33/195 (16%)
Query: 153 QKVLNNCKTTADELKKLIRLQTEKLQSIEKQLESNEIEIRFWEQKYNSNLEEEIVRLEQK 212
Q+ L++ + ++ +K R E+L++++ +LE ++ +Q+ + E+E+ L++
Sbjct: 1124 QEDLDSERAARNKAEKQKRDLGEELEALKTELEDT-LDSTATQQELRAKREQEVTVLKKA 1182
Query: 213 IKRNDVEIEEEEFWENELQIEQENEKQLKDQLQEIRQKITECENKLKDYLAQIRTMESGL 272
+ +EE +E Q+ QE+RQK + +L + L Q + ++ L
Sbjct: 1183 L--------DEETRSHEAQV------------QEMRQKHAQAVEELTEQLEQFKRAKANL 1222
Query: 273 EAEKLQREVQEAQVNEEEVKGKIGKVKGEIDIQGQQSLRLENGIKAVERSLGQATKRLQD 332
+ K E + A + GE+ + GQ +E+ K +E + + + D
Sbjct: 1223 DKNKQTLEKENAD------------LAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSD 1270
Query: 333 KEQELEQLTKELRQV 347
E+ +L ++ ++
Sbjct: 1271 GERARAELNDKVHKL 1285
Score = 40.8 bits (94), Expect = 0.002
Identities = 43/208 (20%), Positives = 95/208 (45%), Gaps = 14/208 (6%)
Query: 147 KETEFKQKVLNNCKTTADEL---KKLIRLQTEKLQSIEKQLESNEIEIRFWEQKYNSN-- 201
+E E KQ + + T +L KK ++ ++++E+ + + EI Q+Y
Sbjct: 1354 EEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAA 1413
Query: 202 ----LEEEIVRLEQKIKRNDVEIEEEEFWENELQIEQENEKQLKDQLQEIRQKITECENK 257
LE+ RL+Q++ V+++ + + L+ +Q QL + + I K + ++
Sbjct: 1414 AYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDR 1473
Query: 258 LKDYLAQIRTMESGLEAEKLQREVQEAQVNEEEVKGKIGKVKGEIDIQGQQSLRLENGIK 317
A+ E +A L R ++EA +EE++ +K E++ + +
Sbjct: 1474 -----AEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVH 1528
Query: 318 AVERSLGQATKRLQDKEQELEQLTKELR 345
+E+S ++++ + +LE+L EL+
Sbjct: 1529 ELEKSKRALETQMEEMKTQLEELEDELQ 1556
Score = 39.7 bits (91), Expect = 0.005
Identities = 46/237 (19%), Positives = 112/237 (47%), Gaps = 19/237 (8%)
Query: 119 SIKRREPKRKSLTFTGGAKGLMDIFGKGKETEFKQKVLNNCKTTADELKKLIRLQTEKLQ 178
+I+ + K+K F + L + GK+ F++++ N + ++ +L+ K
Sbjct: 1370 NIQLSDSKKKLQDFASTVEALEE----GKK-RFQKEIENLTQQYEEKAAAYDKLEKTK-N 1423
Query: 179 SIEKQLESNEIEIRFWEQKYNSNLEEEIVRLEQKIKR----NDVEIEEEEFWENELQIEQ 234
++++L+ +++ Q SNLE++ + +Q + + +E + E E + ++
Sbjct: 1424 RLQQELDDLVVDLDNQRQLV-SNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKE 1482
Query: 235 ENEKQLKDQLQEIRQKITECENKLKDYLAQIRTMES-----GLEAEKLQREVQEAQVNEE 289
L L+E + E E K A++ + S G +L++ + + E
Sbjct: 1483 TKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQME 1542
Query: 290 EVKGKIGKVKGEIDIQGQQSLRLENGIKAVERSLGQATKRLQDKEQELEQLTKELRQ 346
E+K ++ +++ E+ LRLE ++A++ GQ + LQ ++++ E+ ++L++
Sbjct: 1543 EMKTQLEELEDELQATEDAKLRLEVNMQALK---GQFERDLQARDEQNEEKRRQLQR 1596
Score = 37.4 bits (85), Expect = 0.024
Identities = 44/268 (16%), Positives = 119/268 (44%), Gaps = 12/268 (4%)
Query: 112 LRPQIDKSIKRREPKRKSLTFTGGAKGLMDIFGKGKETEFKQKVLNNCKTTADELKKLIR 171
L Q+++ + E L T AK +++ + + +F++ + + ++ ++L R
Sbjct: 1537 LETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQR 1596
Query: 172 LQTEKLQSIEKQLESNEIEIRFWEQKYNSNLEEEIVRLEQKIKRNDVEIEEEEFWENELQ 231
E +E + + + ++K +L++ ++ + IK + I++ + +++
Sbjct: 1597 QLHEYETELEDERKQRALAAAA-KKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMK 1655
Query: 232 IEQENEKQLKDQLQEIRQKITECENKLKDYLAQIRTMESGLEAEKLQREVQEAQVNEEEV 291
Q + + EI E E K K A + ++ L A + R+ +A + +EE+
Sbjct: 1656 DFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARK--QADLEKEEL 1713
Query: 292 KGKIGKVKGEIDIQGQQSLRLENGIKAVERSLGQATKRLQDKEQELEQLTKELRQVNLQQ 351
++ + G+ +L+ E + +E + Q + L++++ +E ++ +R+ Q
Sbjct: 1714 AEELAS-----SLSGRNALQDEK--RRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQ- 1765
Query: 352 FIQQTGTKVTVLPAEPIEIEASHADIER 379
+Q ++ + + E++ +ER
Sbjct: 1766 -AEQLSNELATERSTAQKNESARQQLER 1792
>gi|96975038 coiled-coil domain containing 100 [Homo sapiens]
Length = 986
Score = 58.5 bits (140), Expect = 1e-08
Identities = 51/219 (23%), Positives = 108/219 (49%), Gaps = 23/219 (10%)
Query: 141 DIFGKGKETEFKQKVLNNCKTTADELKK-------LIRLQTEKLQSIEKQLESNEIEIRF 193
DIF E + KQK L + + A+E KK L++ + + +E +L+ I++
Sbjct: 666 DIF----ENQLKQKELAHMQALAEEWKKRDRERESLVKKKVAEYTILEGKLQKTLIDLEK 721
Query: 194 WEQKY---NSNLEEEIVRLEQKIKRNDVEIEE-----EEFWENELQIEQENEKQLKDQLQ 245
EQ+ S L+ E L+ + +RN E+++ +E +++++E+ KQL++
Sbjct: 722 REQQLASVESELQREKKELQSERQRNLQELQDSIRRAKEDCIHQVELERLKIKQLEEDKH 781
Query: 246 EIRQKITECENK---LKDYLAQIRTMESGLEAEKLQREVQEAQVNEEEVKGKI-GKVKGE 301
++Q++ + ENK L+ Q + ++ +LQ E+ + + E++ K+ K +
Sbjct: 782 RLQQQLNDAENKYKILEKEFQQFKDQQNNKPEIRLQSEINLLTLEKVELERKLESATKSK 841
Query: 302 IDIQGQQSLRLENGIKAVERSLGQATKRLQDKEQELEQL 340
+ + Q L+ + +R RL+ +++ELEQ+
Sbjct: 842 LHYKQQWGRALKELARLKQREQESQMARLKKQQEELEQM 880
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 58.2 bits (139), Expect = 1e-08
Identities = 40/177 (22%), Positives = 95/177 (53%), Gaps = 16/177 (9%)
Query: 173 QTEKLQSIEKQLESNEIEIRFWEQKYNSNLEEEIVRLEQKIKRNDVEIEEEEFWENELQI 232
Q EK++ E+++ E E + W Q EE + ++KI+ + E+EE W E +I
Sbjct: 482 QEEKIREQEEKIR--EQEEKMWRQ-------EEKIHEQEKIREEEKRQEQEEMWRQEEKI 532
Query: 233 -EQENEKQLKDQLQEIRQKITECENKLKDYLAQIRTMESGL--EAEKLQREVQEAQVNEE 289
EQE + K+++ E +KI + E K+ ++ E + + EK+ R+ ++ + EE
Sbjct: 533 REQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEE 592
Query: 290 EVKGKIGKVKGEIDIQGQQSLRLENGIKAVERSLGQATKRLQDKEQELEQLTKELRQ 346
+++ + K++ + ++ +Q E + E + + +++Q++E+++ + +++R+
Sbjct: 593 KIREQEEKIREQEEMTQEQ----EEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIRE 645
Score = 57.4 bits (137), Expect = 2e-08
Identities = 51/193 (26%), Positives = 97/193 (50%), Gaps = 18/193 (9%)
Query: 173 QTEKLQSIEKQLESNEIEIRFWEQKYNSNLEEEIVRLEQKI--KRNDVEIEEEEFWENEL 230
Q EK+Q E++++ E +IR E+K EE++ R E+ + K + +EE WE E
Sbjct: 366 QEEKIQEWEEKIQEQEEKIREQEEKIREQ-EEKMRRQEEMMWEKEEKMRRQEEMMWEKE- 423
Query: 231 QIEQENEKQLKDQLQEIRQKITECENKLKDYLAQIRTMESGLEAEKLQREVQEAQVNEEE 290
E ++ ++ + E +KI E E K+ + +IR E + E+ RE ++ Q E +
Sbjct: 424 ----EKMRRQEEMMWEKEEKIRELEEKMHEQ-EKIREQEEKRQEEEKIREQEKRQEQEAK 478
Query: 291 V---KGKIGKVKGEIDIQGQQSLRLENGIKAVERSLGQATKRLQDKEQELEQLTKELRQV 347
+ + KI + + +I Q ++ R E I E+ R ++K QE E++ ++ ++
Sbjct: 479 MWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKI------REEEKRQEQEEMWRQEEKI 532
Query: 348 NLQQFIQQTGTKV 360
Q+ I + K+
Sbjct: 533 REQEEIWRQKEKI 545
Score = 55.5 bits (132), Expect = 8e-08
Identities = 47/204 (23%), Positives = 102/204 (50%), Gaps = 22/204 (10%)
Query: 165 ELKKLIRLQTEKLQSIEK---QLESNEIEIRFWEQKYNSNLEEEIVRLEQKIKRNDVEI- 220
E ++ IR EK+ EK Q E + E + EQ+ E ++ R E+KI+ + +I
Sbjct: 435 EKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIR 494
Query: 221 -EEEEFWENE------LQIEQENEKQLKDQLQEIRQKITECE------NKLKDYLAQIRT 267
+EE+ W E +I +E ++Q ++++ +KI E E K+ + +IR
Sbjct: 495 EQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRK 554
Query: 268 MESGLEAEKLQREVQEAQVNEEEVK-----GKIGKVKGEIDIQGQQSLRLENGIKAVERS 322
E + ++ + QE ++ E+E K KI + + +I Q ++ E + E
Sbjct: 555 QEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEK 614
Query: 323 LGQATKRLQDKEQELEQLTKELRQ 346
+G+ +++ ++E+++++ +++R+
Sbjct: 615 MGEQEEKMCEQEEKMQEQEEKMRR 638
Score = 53.1 bits (126), Expect = 4e-07
Identities = 54/192 (28%), Positives = 92/192 (47%), Gaps = 18/192 (9%)
Query: 165 ELKKLIRLQTEKLQSIEKQLESNEIEIRFWEQKYNSNLEEEIV-RLEQKIKRNDVEIEEE 223
E ++ IR Q EK++ E+++ E WE++ +EE++ E+K++R +EE
Sbjct: 379 EQEEKIREQEEKIREQEEKMRRQ--EEMMWEKEEKMRRQEEMMWEKEEKMRR-----QEE 431
Query: 224 EFWENELQI--------EQENEKQLKDQLQEIRQKITECENKLKDYLAQIRTMESGLEAE 275
WE E +I EQE ++ +++ QE +KI E E + + R E E E
Sbjct: 432 MMWEKEEKIRELEEKMHEQEKIREQEEKRQE-EEKIREQEKRQEQEAKMWRQEEKIREQE 490
Query: 276 KLQREVQEAQVNEEEVKGKIGKVKGEIDIQGQQSL-RLENGIKAVERSLGQATKRLQDKE 334
+ RE +E +EE + K++ E Q Q+ + R E I+ E Q K + +E
Sbjct: 491 EKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEE 550
Query: 335 QELEQLTKELRQ 346
+ +Q K RQ
Sbjct: 551 KIRKQEEKMWRQ 562
Score = 53.1 bits (126), Expect = 4e-07
Identities = 40/185 (21%), Positives = 98/185 (52%), Gaps = 13/185 (7%)
Query: 167 KKLIRLQTEKLQSIEKQLESNEIEIRFWEQKYNSNLEEEIVRLEQKIKRNDVEIEEEEFW 226
K+ I Q EK++ E+++ E ++ E+K EE++ R E+KI+ +EE+
Sbjct: 542 KEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQ-EEKVWRQEEKIRE-----QEEKIR 595
Query: 227 ENELQIEQENE--KQLKDQLQEIRQKITECENKLKDYLAQIRTMESGLEAEKLQREVQEA 284
E E +I ++ E ++ ++++ E +K+ E E K+++ ++R E + ++ + QE
Sbjct: 596 EQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEE 655
Query: 285 QVNE-----EEVKGKIGKVKGEIDIQGQQSLRLENGIKAVERSLGQATKRLQDKEQELEQ 339
++ E +E + K+ + + ++ Q ++ E ++ E + + RL+ +E+++++
Sbjct: 656 KIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQE 715
Query: 340 LTKEL 344
+ L
Sbjct: 716 HQEHL 720
Score = 52.4 bits (124), Expect = 7e-07
Identities = 50/194 (25%), Positives = 94/194 (48%), Gaps = 29/194 (14%)
Query: 160 KTTADELKKLIRLQTEKLQSIEKQLESNEIEIRFWEQKYNSNLEEEIVRLEQKIKRNDVE 219
K E ++ IR Q EK+ E+++ E +IR E+K EE+I E+KI+ + +
Sbjct: 542 KEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQ-EEKIREQEEKIREQEEK 600
Query: 220 IEEEEFWENELQIE---------------QENEKQLKDQLQEIRQKITECENKLKDYLAQ 264
I E+E E + + QE E++++ Q +KI E E K+++ +
Sbjct: 601 IREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQ----EEKIREQEKKIREQEEK 656
Query: 265 IRTMESGLEAEKLQREVQEAQVNEEEVKGKIGKVKGEIDIQGQQSLRLENGIKAVERSLG 324
IR E E++ +E +E +EE K+ + + ++ Q ++ R E + E L
Sbjct: 657 IR------EQEEMMQEQEEKMWEQEE---KMCEQEEKMQEQEEKMRRQEEKMWEQEVRLR 707
Query: 325 QATKRLQDKEQELE 338
Q +++Q+ ++ LE
Sbjct: 708 QQEEKMQEHQEHLE 721
Score = 52.0 bits (123), Expect = 9e-07
Identities = 53/258 (20%), Positives = 121/258 (46%), Gaps = 19/258 (7%)
Query: 104 QSLPPLAKLRPQIDKSIKRREPKRKSLTFTGGAKGLMDIFGKGKETEFKQKVLNNCKTTA 163
Q+L +A + + D+ I+ +R +L+ + D K K + ++K L ++
Sbjct: 240 QALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEK-LQLVESEK 298
Query: 164 DELKKLIRLQTEKLQSIEKQLESNEIEIRFWEQKYNSNLEEEIVRLEQKIKRNDVEIEEE 223
E++ ++ KL+ + L ++ Q +L +E+ + K++ ++EE
Sbjct: 299 SEIQLNVKELKRKLERAKLLLPQQQL------QAEADHLGKELQSVSAKLQ---AQVEEN 349
Query: 224 EFWENELQIEQENEKQLKDQLQEIRQKITECENKLKDYLAQIRTMESGL-EAEKLQREVQ 282
E W Q ++E + ++++QE +KI E E K+++ +IR E + E++ E +
Sbjct: 350 ELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKE 409
Query: 283 EAQVNEEEVKGKIGKVKGEIDIQGQQSLRLENGIKAVERSLGQATKRLQDKEQELEQLTK 342
E +EE+ + + + ++ Q + E I+ +E + + Q+K +E E+ +
Sbjct: 410 EKMRRQEEM---MWEKEEKMRRQEEMMWEKEEKIRELEEKMHE-----QEKIREQEEKRQ 461
Query: 343 ELRQVNLQQFIQQTGTKV 360
E ++ Q+ Q+ K+
Sbjct: 462 EEEKIREQEKRQEQEAKM 479
Score = 50.8 bits (120), Expect = 2e-06
Identities = 42/202 (20%), Positives = 102/202 (50%), Gaps = 25/202 (12%)
Query: 173 QTEKLQSIEKQLESNEI---------EIRFWEQKYNSNLEEEIVRL-EQKIKRNDVEI-- 220
+ EK++ EK+ E E+ + W QK + +EE +R E+K+ R + ++
Sbjct: 509 EQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHD 568
Query: 221 -------EEEEFWENELQIEQENEK--QLKDQLQEIRQKITECENKLKDYLAQIRTMESG 271
+EE+ W E +I ++ EK + +++++E + E E K+ + ++ E
Sbjct: 569 QEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEK 628
Query: 272 LEAEKLQREVQEAQVNEEEVKGKIGKVKGEIDIQGQQSLRLENGIKAVERSLGQATKRLQ 331
++ ++ + QE ++ E+E KI + + +I Q + E + E + + +++Q
Sbjct: 629 MQEQEEKMRRQEEKIREQE--KKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQ 686
Query: 332 DKEQELEQLTKEL--RQVNLQQ 351
++E+++ + +++ ++V L+Q
Sbjct: 687 EQEEKMRRQEEKMWEQEVRLRQ 708
Score = 43.5 bits (101), Expect = 3e-04
Identities = 42/162 (25%), Positives = 75/162 (46%), Gaps = 31/162 (19%)
Query: 95 RIPERTLYRQSLPPLAKLRPQIDKSIKRREPKRKSLTFTGGAKGLMDIFGKGKETEFKQK 154
R E ++RQ K+R Q +K ++ E R+ T + M G+ +E +Q+
Sbjct: 574 REQEEKVWRQE----EKIREQEEKIREQEEKIREQEEMTQEQEEKM---GEQEEKMCEQE 626
Query: 155 VLNNCKTTADELKKLIRLQTEKLQSIEKQLESNEIEIR------------FWEQKYN-SN 201
E ++ +R Q EK++ EK++ E +IR WEQ+
Sbjct: 627 ------EKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCE 680
Query: 202 LEEEIVRLEQKIKRNDVEIEEEEFWENELQIEQENEKQLKDQ 243
EE++ E+K++R +EE+ WE E+++ Q+ EK + Q
Sbjct: 681 QEEKMQEQEEKMRR-----QEEKMWEQEVRLRQQEEKMQEHQ 717
Score = 37.7 bits (86), Expect = 0.018
Identities = 27/154 (17%), Positives = 72/154 (46%), Gaps = 4/154 (2%)
Query: 197 KYNSNLEEEIVRLEQKIKRNDVEIEEEEFWENELQIEQENEKQLKDQLQEIRQKITE--- 253
K+ LE+ + + + K+ D IEE + L +E ++L+E K+ E
Sbjct: 233 KFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQ 292
Query: 254 -CENKLKDYLAQIRTMESGLEAEKLQREVQEAQVNEEEVKGKIGKVKGEIDIQGQQSLRL 312
E++ + ++ ++ LE KL Q+ Q + + ++ V ++ Q +++
Sbjct: 293 LVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELW 352
Query: 313 ENGIKAVERSLGQATKRLQDKEQELEQLTKELRQ 346
+ E + + +++Q+ E+++++ +++R+
Sbjct: 353 NRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIRE 386
>gi|221316624 dystonin isoform 4 [Homo sapiens]
Length = 5526
Score = 58.2 bits (139), Expect = 1e-08
Identities = 70/297 (23%), Positives = 130/297 (43%), Gaps = 33/297 (11%)
Query: 105 SLPPLAKLRPQIDKSIKRREPKRKSLT--FTGGAKGLMDIFGKGKETEFKQKV----LNN 158
SL L + +++ K K K L + +K L D GK KQK+ ++
Sbjct: 1453 SLKRLEEEEKSLEEEKKEHVEKAKELQKWVSNISKTLKDAEKAGKPPFSKQKISSEEIST 1512
Query: 159 CKTTADELKKLIRLQTEKLQSIEKQLESNEIE--IRFWEQKYNSNLEEEIVRLEQKIKRN 216
K E + I+L K E NE+E ++ ++ YN E + +L++
Sbjct: 1513 KKEQLSEALQTIQLFLAKHGDKMTDEERNELEKQVKTLQESYNLLFSESLKQLQESQTSG 1572
Query: 217 DVEIEEEEFWENELQIEQENEKQLKDQLQEIRQKITECENKLKDYLAQIRTMESGLEAEK 276
DV++EE +I E +++ K++LQ I +T+ EN+L + + +E +K
Sbjct: 1573 DVKVEE--------KIVAERQQEYKEKLQGICDLLTQTENRLIGHQEAFMIGDGTVELKK 1624
Query: 277 LQREVQEAQVNEEEVKGKIGKVKGEIDIQGQQSLRLENGIK-------AVERSLGQATKR 329
Q + +E Q + + + +V ++ ++ ENG K +E+ L +A +
Sbjct: 1625 YQSKQEELQKDMQGSAQALAEV-----VKNTENFLKENGEKLSQEDKALIEQKLNEAKIK 1679
Query: 330 LQDKEQELEQLTKELRQVNLQQFIQQTGTKVTVLPAEPIEIEASHADIERGIIILSD 386
+ + EQ KEL +V + I++ KV + ++E S IE + LS+
Sbjct: 1680 CEQLNLKAEQSKKELDKV-VTTAIKEETEKVAAVK----QLEESKTKIENLLDWLSN 1731
Score = 37.0 bits (84), Expect = 0.031
Identities = 40/194 (20%), Positives = 86/194 (44%), Gaps = 23/194 (11%)
Query: 160 KTTADELKKLIRLQTEKLQSIEKQLESNEIEIRFWEQKYN--SNLEEEIVRLEQKIKRND 217
K AD+L + + ++ + + LE ++++ Y+ + +++ ++KI+ N
Sbjct: 1290 KEKADQLVERWQNVHVQIDNRLRDLEGIGKSLKYYRDTYHPLDDWIQQVETTQRKIQENQ 1349
Query: 218 VEIEEEEFWENELQIEQENEKQLKDQLQEIRQKITECENKLKDYLAQIRTMESGLEAEKL 277
E + L + +K L +++ + K+ EC+ + Y A ++ E L
Sbjct: 1350 PENSKT------LATQLNQQKMLVSEIEMKQSKMDECQKYAEQYSATVKDYE-------L 1396
Query: 278 QREVQEAQVNEEE---VKGKIGKVKGEIDIQGQQSLR-----LENGIKAVERSLGQATKR 329
Q A V+ ++ VK + + ++ IQ LR L + + G + KR
Sbjct: 1397 QTMTYRAMVDSQQKSPVKRRRMQSSADLIIQEFMDLRTRYTALVTLMTQYIKFAGDSLKR 1456
Query: 330 LQDKEQELEQLTKE 343
L+++E+ LE+ KE
Sbjct: 1457 LEEEEKSLEEEKKE 1470
Score = 32.0 bits (71), Expect = 0.99
Identities = 41/192 (21%), Positives = 86/192 (44%), Gaps = 27/192 (14%)
Query: 168 KLIRLQTEKLQSIEKQLESNEIEIRFWEQKYNSNLEEEIVRLEQKIKRNDVE-----IEE 222
K+ L T KL ++K E + ++ W QK N + +Q D E +E+
Sbjct: 2447 KIAELNT-KLSKLQKAQEESSAMMQ-WLQKMNKTA----TKWQQTPAPTDTEAVKTQVEQ 2500
Query: 223 EEFWENELQIEQENEKQLKDQLQEI-------------RQKITECENKLKDYLAQIRTME 269
+ +E EL+ ++LKD+L E+ +Q +TE ++K ++ L Q+ T++
Sbjct: 2501 NKSFEAELKQNVNKVQELKDKLTELLEENPDTPEAPRWKQMLTEIDSKWQE-LNQL-TID 2558
Query: 270 SGLEAEKLQREVQEAQVNEEEVKGKIGKVKGEIDIQGQQSLRLENGIKAVERSLGQATKR 329
+ E+ + + Q E ++K + + + + + G S+ N + + + +
Sbjct: 2559 RQQKLEESSNNLTQFQTVEAQLKQWLVEKELMVSVLGPLSID-PNMLNTQRQQVQILLQE 2617
Query: 330 LQDKEQELEQLT 341
++ + EQLT
Sbjct: 2618 FATRKPQYEQLT 2629
Score = 30.8 bits (68), Expect = 2.2
Identities = 30/95 (31%), Positives = 48/95 (50%), Gaps = 10/95 (10%)
Query: 227 ENELQIEQENEKQ-LKDQLQEIR-------QKITECENKLKDYLAQIRTMESGLEAEKLQ 278
EN L Q +EK L+ QL I+ +++ E ENKLK+ L + ++ + E L
Sbjct: 2854 ENLLLKTQGSEKAALQLQLNTIKTNWDTFNKQVKERENKLKESLE--KALKYKEQVETLW 2911
Query: 279 REVQEAQVNEEEVKGKIGKVKGEIDIQGQQSLRLE 313
+ + Q N EE+K + +GE I +SL+ E
Sbjct: 2912 PWIDKCQNNLEEIKFCLDPAEGENSIAKLKSLQKE 2946
Score = 30.0 bits (66), Expect = 3.8
Identities = 44/231 (19%), Positives = 101/231 (43%), Gaps = 41/231 (17%)
Query: 148 ETEFKQKVLNNCKTTADELKKLIRLQTEKLQSIEKQL--------ESNEIEIRFWEQK-- 197
+ E + + L A + + + E L +IEK+L +++++E + + K
Sbjct: 3431 KAETRNRQLEGISVVAQQFHETLEPLNEWLTTIEKRLVNCEPIGTQASKLEEQIAQHKAL 3490
Query: 198 ------YNSNLEEEIVRLEQKIK----RNDVEIEEEEF-----WENELQIEQENEKQLKD 242
+N +L + V + Q +K R D ++ + + W E+Q + + +L
Sbjct: 3491 EDDIINHNKHLHQA-VSIGQSLKVLSSREDKDMVQSKLDFSQVWYIEIQEKSHSRSELLQ 3549
Query: 243 QLQEIRQKITECENKLKDYLAQIRTMESGLEA-----EKLQREVQEAQVNEEEVKGKIGK 297
Q + E E +L ++L ++ S L E L ++ E +V +E++ +
Sbjct: 3550 QALCNAKIFGEDEVELMNWLNEVHDKLSKLSVQDYSTEGLWKQQSELRVLQEDILLR--- 3606
Query: 298 VKGEIDIQGQQSLRLENGIKAVERSLGQATKRLQDKEQELEQLTKELRQVN 348
K +D L NG++ ++++ G +QDK + ++ K++ +++
Sbjct: 3607 -KQNVD------QALLNGLELLKQTTGDEVLIIQDKLEAIKARYKDITKLS 3650
>gi|221316622 dystonin isoform 3 [Homo sapiens]
Length = 5537
Score = 58.2 bits (139), Expect = 1e-08
Identities = 70/297 (23%), Positives = 130/297 (43%), Gaps = 33/297 (11%)
Query: 105 SLPPLAKLRPQIDKSIKRREPKRKSLT--FTGGAKGLMDIFGKGKETEFKQKV----LNN 158
SL L + +++ K K K L + +K L D GK KQK+ ++
Sbjct: 1464 SLKRLEEEEKSLEEEKKEHVEKAKELQKWVSNISKTLKDAEKAGKPPFSKQKISSEEIST 1523
Query: 159 CKTTADELKKLIRLQTEKLQSIEKQLESNEIE--IRFWEQKYNSNLEEEIVRLEQKIKRN 216
K E + I+L K E NE+E ++ ++ YN E + +L++
Sbjct: 1524 KKEQLSEALQTIQLFLAKHGDKMTDEERNELEKQVKTLQESYNLLFSESLKQLQESQTSG 1583
Query: 217 DVEIEEEEFWENELQIEQENEKQLKDQLQEIRQKITECENKLKDYLAQIRTMESGLEAEK 276
DV++EE +I E +++ K++LQ I +T+ EN+L + + +E +K
Sbjct: 1584 DVKVEE--------KIVAERQQEYKEKLQGICDLLTQTENRLIGHQEAFMIGDGTVELKK 1635
Query: 277 LQREVQEAQVNEEEVKGKIGKVKGEIDIQGQQSLRLENGIK-------AVERSLGQATKR 329
Q + +E Q + + + +V ++ ++ ENG K +E+ L +A +
Sbjct: 1636 YQSKQEELQKDMQGSAQALAEV-----VKNTENFLKENGEKLSQEDKALIEQKLNEAKIK 1690
Query: 330 LQDKEQELEQLTKELRQVNLQQFIQQTGTKVTVLPAEPIEIEASHADIERGIIILSD 386
+ + EQ KEL +V + I++ KV + ++E S IE + LS+
Sbjct: 1691 CEQLNLKAEQSKKELDKV-VTTAIKEETEKVAAVK----QLEESKTKIENLLDWLSN 1742
Score = 37.0 bits (84), Expect = 0.031
Identities = 40/194 (20%), Positives = 86/194 (44%), Gaps = 23/194 (11%)
Query: 160 KTTADELKKLIRLQTEKLQSIEKQLESNEIEIRFWEQKYN--SNLEEEIVRLEQKIKRND 217
K AD+L + + ++ + + LE ++++ Y+ + +++ ++KI+ N
Sbjct: 1301 KEKADQLVERWQNVHVQIDNRLRDLEGIGKSLKYYRDTYHPLDDWIQQVETTQRKIQENQ 1360
Query: 218 VEIEEEEFWENELQIEQENEKQLKDQLQEIRQKITECENKLKDYLAQIRTMESGLEAEKL 277
E + L + +K L +++ + K+ EC+ + Y A ++ E L
Sbjct: 1361 PENSKT------LATQLNQQKMLVSEIEMKQSKMDECQKYAEQYSATVKDYE-------L 1407
Query: 278 QREVQEAQVNEEE---VKGKIGKVKGEIDIQGQQSLR-----LENGIKAVERSLGQATKR 329
Q A V+ ++ VK + + ++ IQ LR L + + G + KR
Sbjct: 1408 QTMTYRAMVDSQQKSPVKRRRMQSSADLIIQEFMDLRTRYTALVTLMTQYIKFAGDSLKR 1467
Query: 330 LQDKEQELEQLTKE 343
L+++E+ LE+ KE
Sbjct: 1468 LEEEEKSLEEEKKE 1481
Score = 32.0 bits (71), Expect = 0.99
Identities = 41/192 (21%), Positives = 86/192 (44%), Gaps = 27/192 (14%)
Query: 168 KLIRLQTEKLQSIEKQLESNEIEIRFWEQKYNSNLEEEIVRLEQKIKRNDVE-----IEE 222
K+ L T KL ++K E + ++ W QK N + +Q D E +E+
Sbjct: 2458 KIAELNT-KLSKLQKAQEESSAMMQ-WLQKMNKTA----TKWQQTPAPTDTEAVKTQVEQ 2511
Query: 223 EEFWENELQIEQENEKQLKDQLQEI-------------RQKITECENKLKDYLAQIRTME 269
+ +E EL+ ++LKD+L E+ +Q +TE ++K ++ L Q+ T++
Sbjct: 2512 NKSFEAELKQNVNKVQELKDKLTELLEENPDTPEAPRWKQMLTEIDSKWQE-LNQL-TID 2569
Query: 270 SGLEAEKLQREVQEAQVNEEEVKGKIGKVKGEIDIQGQQSLRLENGIKAVERSLGQATKR 329
+ E+ + + Q E ++K + + + + + G S+ N + + + +
Sbjct: 2570 RQQKLEESSNNLTQFQTVEAQLKQWLVEKELMVSVLGPLSID-PNMLNTQRQQVQILLQE 2628
Query: 330 LQDKEQELEQLT 341
++ + EQLT
Sbjct: 2629 FATRKPQYEQLT 2640
Score = 30.8 bits (68), Expect = 2.2
Identities = 30/95 (31%), Positives = 48/95 (50%), Gaps = 10/95 (10%)
Query: 227 ENELQIEQENEKQ-LKDQLQEIR-------QKITECENKLKDYLAQIRTMESGLEAEKLQ 278
EN L Q +EK L+ QL I+ +++ E ENKLK+ L + ++ + E L
Sbjct: 2865 ENLLLKTQGSEKAALQLQLNTIKTNWDTFNKQVKERENKLKESLE--KALKYKEQVETLW 2922
Query: 279 REVQEAQVNEEEVKGKIGKVKGEIDIQGQQSLRLE 313
+ + Q N EE+K + +GE I +SL+ E
Sbjct: 2923 PWIDKCQNNLEEIKFCLDPAEGENSIAKLKSLQKE 2957
Score = 30.0 bits (66), Expect = 3.8
Identities = 44/231 (19%), Positives = 101/231 (43%), Gaps = 41/231 (17%)
Query: 148 ETEFKQKVLNNCKTTADELKKLIRLQTEKLQSIEKQL--------ESNEIEIRFWEQK-- 197
+ E + + L A + + + E L +IEK+L +++++E + + K
Sbjct: 3442 KAETRNRQLEGISVVAQQFHETLEPLNEWLTTIEKRLVNCEPIGTQASKLEEQIAQHKAL 3501
Query: 198 ------YNSNLEEEIVRLEQKIK----RNDVEIEEEEF-----WENELQIEQENEKQLKD 242
+N +L + V + Q +K R D ++ + + W E+Q + + +L
Sbjct: 3502 EDDIINHNKHLHQA-VSIGQSLKVLSSREDKDMVQSKLDFSQVWYIEIQEKSHSRSELLQ 3560
Query: 243 QLQEIRQKITECENKLKDYLAQIRTMESGLEA-----EKLQREVQEAQVNEEEVKGKIGK 297
Q + E E +L ++L ++ S L E L ++ E +V +E++ +
Sbjct: 3561 QALCNAKIFGEDEVELMNWLNEVHDKLSKLSVQDYSTEGLWKQQSELRVLQEDILLR--- 3617
Query: 298 VKGEIDIQGQQSLRLENGIKAVERSLGQATKRLQDKEQELEQLTKELRQVN 348
K +D L NG++ ++++ G +QDK + ++ K++ +++
Sbjct: 3618 -KQNVD------QALLNGLELLKQTTGDEVLIIQDKLEAIKARYKDITKLS 3661
>gi|221316618 dystonin isoform 2 [Homo sapiens]
Length = 5675
Score = 58.2 bits (139), Expect = 1e-08
Identities = 70/297 (23%), Positives = 130/297 (43%), Gaps = 33/297 (11%)
Query: 105 SLPPLAKLRPQIDKSIKRREPKRKSLT--FTGGAKGLMDIFGKGKETEFKQKV----LNN 158
SL L + +++ K K K L + +K L D GK KQK+ ++
Sbjct: 1602 SLKRLEEEEKSLEEEKKEHVEKAKELQKWVSNISKTLKDAEKAGKPPFSKQKISSEEIST 1661
Query: 159 CKTTADELKKLIRLQTEKLQSIEKQLESNEIE--IRFWEQKYNSNLEEEIVRLEQKIKRN 216
K E + I+L K E NE+E ++ ++ YN E + +L++
Sbjct: 1662 KKEQLSEALQTIQLFLAKHGDKMTDEERNELEKQVKTLQESYNLLFSESLKQLQESQTSG 1721
Query: 217 DVEIEEEEFWENELQIEQENEKQLKDQLQEIRQKITECENKLKDYLAQIRTMESGLEAEK 276
DV++EE +I E +++ K++LQ I +T+ EN+L + + +E +K
Sbjct: 1722 DVKVEE--------KIVAERQQEYKEKLQGICDLLTQTENRLIGHQEAFMIGDGTVELKK 1773
Query: 277 LQREVQEAQVNEEEVKGKIGKVKGEIDIQGQQSLRLENGIK-------AVERSLGQATKR 329
Q + +E Q + + + +V ++ ++ ENG K +E+ L +A +
Sbjct: 1774 YQSKQEELQKDMQGSAQALAEV-----VKNTENFLKENGEKLSQEDKALIEQKLNEAKIK 1828
Query: 330 LQDKEQELEQLTKELRQVNLQQFIQQTGTKVTVLPAEPIEIEASHADIERGIIILSD 386
+ + EQ KEL +V + I++ KV + ++E S IE + LS+
Sbjct: 1829 CEQLNLKAEQSKKELDKV-VTTAIKEETEKVAAVK----QLEESKTKIENLLDWLSN 1880
Score = 37.0 bits (84), Expect = 0.031
Identities = 40/194 (20%), Positives = 86/194 (44%), Gaps = 23/194 (11%)
Query: 160 KTTADELKKLIRLQTEKLQSIEKQLESNEIEIRFWEQKYN--SNLEEEIVRLEQKIKRND 217
K AD+L + + ++ + + LE ++++ Y+ + +++ ++KI+ N
Sbjct: 1439 KEKADQLVERWQNVHVQIDNRLRDLEGIGKSLKYYRDTYHPLDDWIQQVETTQRKIQENQ 1498
Query: 218 VEIEEEEFWENELQIEQENEKQLKDQLQEIRQKITECENKLKDYLAQIRTMESGLEAEKL 277
E + L + +K L +++ + K+ EC+ + Y A ++ E L
Sbjct: 1499 PENSKT------LATQLNQQKMLVSEIEMKQSKMDECQKYAEQYSATVKDYE-------L 1545
Query: 278 QREVQEAQVNEEE---VKGKIGKVKGEIDIQGQQSLR-----LENGIKAVERSLGQATKR 329
Q A V+ ++ VK + + ++ IQ LR L + + G + KR
Sbjct: 1546 QTMTYRAMVDSQQKSPVKRRRMQSSADLIIQEFMDLRTRYTALVTLMTQYIKFAGDSLKR 1605
Query: 330 LQDKEQELEQLTKE 343
L+++E+ LE+ KE
Sbjct: 1606 LEEEEKSLEEEKKE 1619
Score = 32.0 bits (71), Expect = 0.99
Identities = 41/192 (21%), Positives = 86/192 (44%), Gaps = 27/192 (14%)
Query: 168 KLIRLQTEKLQSIEKQLESNEIEIRFWEQKYNSNLEEEIVRLEQKIKRNDVE-----IEE 222
K+ L T KL ++K E + ++ W QK N + +Q D E +E+
Sbjct: 2596 KIAELNT-KLSKLQKAQEESSAMMQ-WLQKMNKTA----TKWQQTPAPTDTEAVKTQVEQ 2649
Query: 223 EEFWENELQIEQENEKQLKDQLQEI-------------RQKITECENKLKDYLAQIRTME 269
+ +E EL+ ++LKD+L E+ +Q +TE ++K ++ L Q+ T++
Sbjct: 2650 NKSFEAELKQNVNKVQELKDKLTELLEENPDTPEAPRWKQMLTEIDSKWQE-LNQL-TID 2707
Query: 270 SGLEAEKLQREVQEAQVNEEEVKGKIGKVKGEIDIQGQQSLRLENGIKAVERSLGQATKR 329
+ E+ + + Q E ++K + + + + + G S+ N + + + +
Sbjct: 2708 RQQKLEESSNNLTQFQTVEAQLKQWLVEKELMVSVLGPLSID-PNMLNTQRQQVQILLQE 2766
Query: 330 LQDKEQELEQLT 341
++ + EQLT
Sbjct: 2767 FATRKPQYEQLT 2778
Score = 30.8 bits (68), Expect = 2.2
Identities = 30/95 (31%), Positives = 48/95 (50%), Gaps = 10/95 (10%)
Query: 227 ENELQIEQENEKQ-LKDQLQEIR-------QKITECENKLKDYLAQIRTMESGLEAEKLQ 278
EN L Q +EK L+ QL I+ +++ E ENKLK+ L + ++ + E L
Sbjct: 3003 ENLLLKTQGSEKAALQLQLNTIKTNWDTFNKQVKERENKLKESLE--KALKYKEQVETLW 3060
Query: 279 REVQEAQVNEEEVKGKIGKVKGEIDIQGQQSLRLE 313
+ + Q N EE+K + +GE I +SL+ E
Sbjct: 3061 PWIDKCQNNLEEIKFCLDPAEGENSIAKLKSLQKE 3095
Score = 30.0 bits (66), Expect = 3.8
Identities = 44/231 (19%), Positives = 101/231 (43%), Gaps = 41/231 (17%)
Query: 148 ETEFKQKVLNNCKTTADELKKLIRLQTEKLQSIEKQL--------ESNEIEIRFWEQK-- 197
+ E + + L A + + + E L +IEK+L +++++E + + K
Sbjct: 3580 KAETRNRQLEGISVVAQQFHETLEPLNEWLTTIEKRLVNCEPIGTQASKLEEQIAQHKAL 3639
Query: 198 ------YNSNLEEEIVRLEQKIK----RNDVEIEEEEF-----WENELQIEQENEKQLKD 242
+N +L + V + Q +K R D ++ + + W E+Q + + +L
Sbjct: 3640 EDDIINHNKHLHQA-VSIGQSLKVLSSREDKDMVQSKLDFSQVWYIEIQEKSHSRSELLQ 3698
Query: 243 QLQEIRQKITECENKLKDYLAQIRTMESGLEA-----EKLQREVQEAQVNEEEVKGKIGK 297
Q + E E +L ++L ++ S L E L ++ E +V +E++ +
Sbjct: 3699 QALCNAKIFGEDEVELMNWLNEVHDKLSKLSVQDYSTEGLWKQQSELRVLQEDILLR--- 3755
Query: 298 VKGEIDIQGQQSLRLENGIKAVERSLGQATKRLQDKEQELEQLTKELRQVN 348
K +D L NG++ ++++ G +QDK + ++ K++ +++
Sbjct: 3756 -KQNVD------QALLNGLELLKQTTGDEVLIIQDKLEAIKARYKDITKLS 3799
>gi|34577047 dystonin isoform 1 [Homo sapiens]
Length = 5497
Score = 58.2 bits (139), Expect = 1e-08
Identities = 70/297 (23%), Positives = 130/297 (43%), Gaps = 33/297 (11%)
Query: 105 SLPPLAKLRPQIDKSIKRREPKRKSLT--FTGGAKGLMDIFGKGKETEFKQKV----LNN 158
SL L + +++ K K K L + +K L D GK KQK+ ++
Sbjct: 1424 SLKRLEEEEKSLEEEKKEHVEKAKELQKWVSNISKTLKDAEKAGKPPFSKQKISSEEIST 1483
Query: 159 CKTTADELKKLIRLQTEKLQSIEKQLESNEIE--IRFWEQKYNSNLEEEIVRLEQKIKRN 216
K E + I+L K E NE+E ++ ++ YN E + +L++
Sbjct: 1484 KKEQLSEALQTIQLFLAKHGDKMTDEERNELEKQVKTLQESYNLLFSESLKQLQESQTSG 1543
Query: 217 DVEIEEEEFWENELQIEQENEKQLKDQLQEIRQKITECENKLKDYLAQIRTMESGLEAEK 276
DV++EE +I E +++ K++LQ I +T+ EN+L + + +E +K
Sbjct: 1544 DVKVEE--------KIVAERQQEYKEKLQGICDLLTQTENRLIGHQEAFMIGDGTVELKK 1595
Query: 277 LQREVQEAQVNEEEVKGKIGKVKGEIDIQGQQSLRLENGIK-------AVERSLGQATKR 329
Q + +E Q + + + +V ++ ++ ENG K +E+ L +A +
Sbjct: 1596 YQSKQEELQKDMQGSAQALAEV-----VKNTENFLKENGEKLSQEDKALIEQKLNEAKIK 1650
Query: 330 LQDKEQELEQLTKELRQVNLQQFIQQTGTKVTVLPAEPIEIEASHADIERGIIILSD 386
+ + EQ KEL +V + I++ KV + ++E S IE + LS+
Sbjct: 1651 CEQLNLKAEQSKKELDKV-VTTAIKEETEKVAAVK----QLEESKTKIENLLDWLSN 1702
Score = 37.0 bits (84), Expect = 0.031
Identities = 40/194 (20%), Positives = 86/194 (44%), Gaps = 23/194 (11%)
Query: 160 KTTADELKKLIRLQTEKLQSIEKQLESNEIEIRFWEQKYN--SNLEEEIVRLEQKIKRND 217
K AD+L + + ++ + + LE ++++ Y+ + +++ ++KI+ N
Sbjct: 1261 KEKADQLVERWQNVHVQIDNRLRDLEGIGKSLKYYRDTYHPLDDWIQQVETTQRKIQENQ 1320
Query: 218 VEIEEEEFWENELQIEQENEKQLKDQLQEIRQKITECENKLKDYLAQIRTMESGLEAEKL 277
E + L + +K L +++ + K+ EC+ + Y A ++ E L
Sbjct: 1321 PENSKT------LATQLNQQKMLVSEIEMKQSKMDECQKYAEQYSATVKDYE-------L 1367
Query: 278 QREVQEAQVNEEE---VKGKIGKVKGEIDIQGQQSLR-----LENGIKAVERSLGQATKR 329
Q A V+ ++ VK + + ++ IQ LR L + + G + KR
Sbjct: 1368 QTMTYRAMVDSQQKSPVKRRRMQSSADLIIQEFMDLRTRYTALVTLMTQYIKFAGDSLKR 1427
Query: 330 LQDKEQELEQLTKE 343
L+++E+ LE+ KE
Sbjct: 1428 LEEEEKSLEEEKKE 1441
Score = 32.0 bits (71), Expect = 0.99
Identities = 41/192 (21%), Positives = 86/192 (44%), Gaps = 27/192 (14%)
Query: 168 KLIRLQTEKLQSIEKQLESNEIEIRFWEQKYNSNLEEEIVRLEQKIKRNDVE-----IEE 222
K+ L T KL ++K E + ++ W QK N + +Q D E +E+
Sbjct: 2418 KIAELNT-KLSKLQKAQEESSAMMQ-WLQKMNKTA----TKWQQTPAPTDTEAVKTQVEQ 2471
Query: 223 EEFWENELQIEQENEKQLKDQLQEI-------------RQKITECENKLKDYLAQIRTME 269
+ +E EL+ ++LKD+L E+ +Q +TE ++K ++ L Q+ T++
Sbjct: 2472 NKSFEAELKQNVNKVQELKDKLTELLEENPDTPEAPRWKQMLTEIDSKWQE-LNQL-TID 2529
Query: 270 SGLEAEKLQREVQEAQVNEEEVKGKIGKVKGEIDIQGQQSLRLENGIKAVERSLGQATKR 329
+ E+ + + Q E ++K + + + + + G S+ N + + + +
Sbjct: 2530 RQQKLEESSNNLTQFQTVEAQLKQWLVEKELMVSVLGPLSID-PNMLNTQRQQVQILLQE 2588
Query: 330 LQDKEQELEQLT 341
++ + EQLT
Sbjct: 2589 FATRKPQYEQLT 2600
Score = 30.8 bits (68), Expect = 2.2
Identities = 30/95 (31%), Positives = 48/95 (50%), Gaps = 10/95 (10%)
Query: 227 ENELQIEQENEKQ-LKDQLQEIR-------QKITECENKLKDYLAQIRTMESGLEAEKLQ 278
EN L Q +EK L+ QL I+ +++ E ENKLK+ L + ++ + E L
Sbjct: 2825 ENLLLKTQGSEKAALQLQLNTIKTNWDTFNKQVKERENKLKESLE--KALKYKEQVETLW 2882
Query: 279 REVQEAQVNEEEVKGKIGKVKGEIDIQGQQSLRLE 313
+ + Q N EE+K + +GE I +SL+ E
Sbjct: 2883 PWIDKCQNNLEEIKFCLDPAEGENSIAKLKSLQKE 2917
Score = 30.0 bits (66), Expect = 3.8
Identities = 44/231 (19%), Positives = 101/231 (43%), Gaps = 41/231 (17%)
Query: 148 ETEFKQKVLNNCKTTADELKKLIRLQTEKLQSIEKQL--------ESNEIEIRFWEQK-- 197
+ E + + L A + + + E L +IEK+L +++++E + + K
Sbjct: 3402 KAETRNRQLEGISVVAQQFHETLEPLNEWLTTIEKRLVNCEPIGTQASKLEEQIAQHKAL 3461
Query: 198 ------YNSNLEEEIVRLEQKIK----RNDVEIEEEEF-----WENELQIEQENEKQLKD 242
+N +L + V + Q +K R D ++ + + W E+Q + + +L
Sbjct: 3462 EDDIINHNKHLHQA-VSIGQSLKVLSSREDKDMVQSKLDFSQVWYIEIQEKSHSRSELLQ 3520
Query: 243 QLQEIRQKITECENKLKDYLAQIRTMESGLEA-----EKLQREVQEAQVNEEEVKGKIGK 297
Q + E E +L ++L ++ S L E L ++ E +V +E++ +
Sbjct: 3521 QALCNAKIFGEDEVELMNWLNEVHDKLSKLSVQDYSTEGLWKQQSELRVLQEDILLR--- 3577
Query: 298 VKGEIDIQGQQSLRLENGIKAVERSLGQATKRLQDKEQELEQLTKELRQVN 348
K +D L NG++ ++++ G +QDK + ++ K++ +++
Sbjct: 3578 -KQNVD------QALLNGLELLKQTTGDEVLIIQDKLEAIKARYKDITKLS 3621
>gi|34577049 dystonin isoform 1eA precursor [Homo sapiens]
Length = 5171
Score = 58.2 bits (139), Expect = 1e-08
Identities = 70/297 (23%), Positives = 130/297 (43%), Gaps = 33/297 (11%)
Query: 105 SLPPLAKLRPQIDKSIKRREPKRKSLT--FTGGAKGLMDIFGKGKETEFKQKV----LNN 158
SL L + +++ K K K L + +K L D GK KQK+ ++
Sbjct: 1098 SLKRLEEEEKSLEEEKKEHVEKAKELQKWVSNISKTLKDAEKAGKPPFSKQKISSEEIST 1157
Query: 159 CKTTADELKKLIRLQTEKLQSIEKQLESNEIE--IRFWEQKYNSNLEEEIVRLEQKIKRN 216
K E + I+L K E NE+E ++ ++ YN E + +L++
Sbjct: 1158 KKEQLSEALQTIQLFLAKHGDKMTDEERNELEKQVKTLQESYNLLFSESLKQLQESQTSG 1217
Query: 217 DVEIEEEEFWENELQIEQENEKQLKDQLQEIRQKITECENKLKDYLAQIRTMESGLEAEK 276
DV++EE +I E +++ K++LQ I +T+ EN+L + + +E +K
Sbjct: 1218 DVKVEE--------KIVAERQQEYKEKLQGICDLLTQTENRLIGHQEAFMIGDGTVELKK 1269
Query: 277 LQREVQEAQVNEEEVKGKIGKVKGEIDIQGQQSLRLENGIK-------AVERSLGQATKR 329
Q + +E Q + + + +V ++ ++ ENG K +E+ L +A +
Sbjct: 1270 YQSKQEELQKDMQGSAQALAEV-----VKNTENFLKENGEKLSQEDKALIEQKLNEAKIK 1324
Query: 330 LQDKEQELEQLTKELRQVNLQQFIQQTGTKVTVLPAEPIEIEASHADIERGIIILSD 386
+ + EQ KEL +V + I++ KV + ++E S IE + LS+
Sbjct: 1325 CEQLNLKAEQSKKELDKV-VTTAIKEETEKVAAVK----QLEESKTKIENLLDWLSN 1376
Score = 37.0 bits (84), Expect = 0.031
Identities = 40/194 (20%), Positives = 86/194 (44%), Gaps = 23/194 (11%)
Query: 160 KTTADELKKLIRLQTEKLQSIEKQLESNEIEIRFWEQKYN--SNLEEEIVRLEQKIKRND 217
K AD+L + + ++ + + LE ++++ Y+ + +++ ++KI+ N
Sbjct: 935 KEKADQLVERWQNVHVQIDNRLRDLEGIGKSLKYYRDTYHPLDDWIQQVETTQRKIQENQ 994
Query: 218 VEIEEEEFWENELQIEQENEKQLKDQLQEIRQKITECENKLKDYLAQIRTMESGLEAEKL 277
E + L + +K L +++ + K+ EC+ + Y A ++ E L
Sbjct: 995 PENSKT------LATQLNQQKMLVSEIEMKQSKMDECQKYAEQYSATVKDYE-------L 1041
Query: 278 QREVQEAQVNEEE---VKGKIGKVKGEIDIQGQQSLR-----LENGIKAVERSLGQATKR 329
Q A V+ ++ VK + + ++ IQ LR L + + G + KR
Sbjct: 1042 QTMTYRAMVDSQQKSPVKRRRMQSSADLIIQEFMDLRTRYTALVTLMTQYIKFAGDSLKR 1101
Query: 330 LQDKEQELEQLTKE 343
L+++E+ LE+ KE
Sbjct: 1102 LEEEEKSLEEEKKE 1115
Score = 32.0 bits (71), Expect = 0.99
Identities = 41/192 (21%), Positives = 86/192 (44%), Gaps = 27/192 (14%)
Query: 168 KLIRLQTEKLQSIEKQLESNEIEIRFWEQKYNSNLEEEIVRLEQKIKRNDVE-----IEE 222
K+ L T KL ++K E + ++ W QK N + +Q D E +E+
Sbjct: 2092 KIAELNT-KLSKLQKAQEESSAMMQ-WLQKMNKTA----TKWQQTPAPTDTEAVKTQVEQ 2145
Query: 223 EEFWENELQIEQENEKQLKDQLQEI-------------RQKITECENKLKDYLAQIRTME 269
+ +E EL+ ++LKD+L E+ +Q +TE ++K ++ L Q+ T++
Sbjct: 2146 NKSFEAELKQNVNKVQELKDKLTELLEENPDTPEAPRWKQMLTEIDSKWQE-LNQL-TID 2203
Query: 270 SGLEAEKLQREVQEAQVNEEEVKGKIGKVKGEIDIQGQQSLRLENGIKAVERSLGQATKR 329
+ E+ + + Q E ++K + + + + + G S+ N + + + +
Sbjct: 2204 RQQKLEESSNNLTQFQTVEAQLKQWLVEKELMVSVLGPLSID-PNMLNTQRQQVQILLQE 2262
Query: 330 LQDKEQELEQLT 341
++ + EQLT
Sbjct: 2263 FATRKPQYEQLT 2274
Score = 30.8 bits (68), Expect = 2.2
Identities = 30/95 (31%), Positives = 48/95 (50%), Gaps = 10/95 (10%)
Query: 227 ENELQIEQENEKQ-LKDQLQEIR-------QKITECENKLKDYLAQIRTMESGLEAEKLQ 278
EN L Q +EK L+ QL I+ +++ E ENKLK+ L + ++ + E L
Sbjct: 2499 ENLLLKTQGSEKAALQLQLNTIKTNWDTFNKQVKERENKLKESLE--KALKYKEQVETLW 2556
Query: 279 REVQEAQVNEEEVKGKIGKVKGEIDIQGQQSLRLE 313
+ + Q N EE+K + +GE I +SL+ E
Sbjct: 2557 PWIDKCQNNLEEIKFCLDPAEGENSIAKLKSLQKE 2591
Score = 30.0 bits (66), Expect = 3.8
Identities = 44/231 (19%), Positives = 101/231 (43%), Gaps = 41/231 (17%)
Query: 148 ETEFKQKVLNNCKTTADELKKLIRLQTEKLQSIEKQL--------ESNEIEIRFWEQK-- 197
+ E + + L A + + + E L +IEK+L +++++E + + K
Sbjct: 3076 KAETRNRQLEGISVVAQQFHETLEPLNEWLTTIEKRLVNCEPIGTQASKLEEQIAQHKAL 3135
Query: 198 ------YNSNLEEEIVRLEQKIK----RNDVEIEEEEF-----WENELQIEQENEKQLKD 242
+N +L + V + Q +K R D ++ + + W E+Q + + +L
Sbjct: 3136 EDDIINHNKHLHQA-VSIGQSLKVLSSREDKDMVQSKLDFSQVWYIEIQEKSHSRSELLQ 3194
Query: 243 QLQEIRQKITECENKLKDYLAQIRTMESGLEA-----EKLQREVQEAQVNEEEVKGKIGK 297
Q + E E +L ++L ++ S L E L ++ E +V +E++ +
Sbjct: 3195 QALCNAKIFGEDEVELMNWLNEVHDKLSKLSVQDYSTEGLWKQQSELRVLQEDILLR--- 3251
Query: 298 VKGEIDIQGQQSLRLENGIKAVERSLGQATKRLQDKEQELEQLTKELRQVN 348
K +D L NG++ ++++ G +QDK + ++ K++ +++
Sbjct: 3252 -KQNVD------QALLNGLELLKQTTGDEVLIIQDKLEAIKARYKDITKLS 3295
>gi|145312241 differentially expressed in FDCP 6 homolog [Homo
sapiens]
Length = 631
Score = 57.8 bits (138), Expect = 2e-08
Identities = 54/180 (30%), Positives = 97/180 (53%), Gaps = 18/180 (10%)
Query: 166 LKKLIRLQTEKLQSIEKQLESNEIEIRFWEQKYNSNLEEEIVRLEQKIKRNDVEIEEEEF 225
++ IRLQ E S+ K L+ E R ++ + EEE++RL+Q EE+E
Sbjct: 307 IQMAIRLQAEGKTSLHKDLKQKRREQREQRERRRAAKEEELLRLQQL-------QEEKER 359
Query: 226 WENELQIEQENEKQLKDQLQEIRQKITECENKLKDYL-AQIRTMESGLEAEKLQREVQ-E 283
EL++ QE ++Q + LQE ++ +L+ L Q+R EAE+ + +Q E
Sbjct: 360 KLQELELLQEAQRQAERLLQEEEERRRSQHRELQQALEGQLR------EAEQARASMQAE 413
Query: 284 AQVNEEEVKGKIGKVK--GEIDIQGQQSLRLENGIKAVERSLGQA-TKRLQDKEQELEQL 340
++ EEE + ++K E+ + Q++L+LE + E S+ A T+ L+++E++L+QL
Sbjct: 414 MELKEEEAARQRQRIKELEEMQQRLQEALQLEVKARRDEESVRIAQTRLLEEEEEKLKQL 473
Score = 34.7 bits (78), Expect = 0.15
Identities = 29/135 (21%), Positives = 63/135 (46%), Gaps = 5/135 (3%)
Query: 148 ETEFKQKVLNNCKTTADELKKLIRLQTEKLQSIEKQLESNEIEIRFWEQKYNSNLEEEIV 207
E E K++ + EL+++ + E LQ +E + +E +R + + EE++
Sbjct: 413 EMELKEEEAARQRQRIKELEEMQQRLQEALQ-LEVKARRDEESVRIAQTRLLEEEEEKLK 471
Query: 208 RLEQKIKRNDVEIEEEEFWENELQIEQENE----KQLKDQLQEIRQKITECENKLKDYLA 263
+L Q + + IE + + ELQ E + +Q + QL+E+RQ + ++
Sbjct: 472 QLMQLKEEQERYIERAQQEKEELQQEMAQQSRSLQQAQQQLEEVRQNRQRADEDVEAAQR 531
Query: 264 QIRTMESGLEAEKLQ 278
++R + ++ +Q
Sbjct: 532 KLRQASTNVKHWNVQ 546
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.131 0.357
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,745,222
Number of Sequences: 37866
Number of extensions: 634395
Number of successful extensions: 10336
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 296
Number of HSP's successfully gapped in prelim test: 1050
Number of HSP's that attempted gapping in prelim test: 4347
Number of HSP's gapped (non-prelim): 3982
length of query: 392
length of database: 18,247,518
effective HSP length: 104
effective length of query: 288
effective length of database: 14,309,454
effective search space: 4121122752
effective search space used: 4121122752
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.