Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 227499990
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|227499990 transmembrane protease, serine 2 isoform 1 [Homo
sapiens]
(529 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|227499990 transmembrane protease, serine 2 isoform 1 [Homo sa... 1128 0.0
gi|205360943 transmembrane protease, serine 2 isoform 2 [Homo sa... 1051 0.0
gi|13173471 transmembrane protease, serine 3 isoform 1 [Homo sap... 333 2e-91
gi|116256363 transmembrane protease, serine 13 [Homo sapiens] 277 2e-74
gi|145701030 transmembrane protease, serine 4 isoform 3 [Homo sa... 252 5e-67
gi|15451940 transmembrane protease, serine 4 isoform 1 [Homo sap... 252 7e-67
gi|170932492 transmembrane protease, serine 5 [Homo sapiens] 249 6e-66
gi|223942069 enterokinase precursor [Homo sapiens] 247 2e-65
gi|29244926 corin [Homo sapiens] 226 4e-59
gi|78191798 plasma kallikrein B1 precursor [Homo sapiens] 217 2e-56
gi|33695155 hepsin [Homo sapiens] 211 1e-54
gi|4504481 hepsin [Homo sapiens] 211 1e-54
gi|194018492 transmembrane protease, serine 11F [Homo sapiens] 208 9e-54
gi|4758508 transmembrane protease, serine 11D [Homo sapiens] 204 2e-52
gi|4503627 coagulation factor XI precursor [Homo sapiens] 203 3e-52
gi|11415040 matriptase [Homo sapiens] 202 5e-52
gi|222831592 transmembrane protease, serine 7 [Homo sapiens] 194 1e-49
gi|23957702 transmembrane protease, serine 6 [Homo sapiens] 194 2e-49
gi|40254871 transmembrane protease, serine 11E [Homo sapiens] 191 1e-48
gi|153791781 transmembrane protease, serine 11E2 [Homo sapiens] 191 1e-48
gi|187761337 transmembrane protease, serine 11B [Homo sapiens] 191 2e-48
gi|148613878 acrosin precursor [Homo sapiens] 190 3e-48
gi|33667063 transmembrane protease, serine 9 [Homo sapiens] 189 4e-48
gi|110815798 ovochymase 1 [Homo sapiens] 189 7e-48
gi|14602457 transmembrane protease, serine 3 isoform 3 [Homo sap... 186 6e-47
gi|167466252 transmembrane protease, serine 11A isoform 2 [Homo ... 183 3e-46
gi|167466250 transmembrane protease, serine 11A isoform 1 [Homo ... 183 3e-46
gi|21614531 testisin isoform 2 [Homo sapiens] 181 1e-45
gi|13994276 marapsin [Homo sapiens] 180 3e-45
gi|117956391 protease, serine, 33 [Homo sapiens] 180 3e-45
>gi|227499990 transmembrane protease, serine 2 isoform 1 [Homo
sapiens]
Length = 529
Score = 1128 bits (2917), Expect = 0.0
Identities = 529/529 (100%), Positives = 529/529 (100%)
Query: 1 MPPAPPGGESGCEERGAAGHIEHSRYLSLLDAVDNSKMALNSGSPPAIGPYYENHGYQPE 60
MPPAPPGGESGCEERGAAGHIEHSRYLSLLDAVDNSKMALNSGSPPAIGPYYENHGYQPE
Sbjct: 1 MPPAPPGGESGCEERGAAGHIEHSRYLSLLDAVDNSKMALNSGSPPAIGPYYENHGYQPE 60
Query: 61 NPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKK 120
NPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKK
Sbjct: 61 NPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKK 120
Query: 121 ALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGE 180
ALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGE
Sbjct: 121 ALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGE 180
Query: 181 DENRCVRLYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKNNFYSSQGIVDD 240
DENRCVRLYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKNNFYSSQGIVDD
Sbjct: 181 DENRCVRLYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKNNFYSSQGIVDD 240
Query: 241 SGSTSFMKLNTSAGNVDIYKKLYHSDACSSKAVVSLRCIACGVNLNSSRQSRIVGGESAL 300
SGSTSFMKLNTSAGNVDIYKKLYHSDACSSKAVVSLRCIACGVNLNSSRQSRIVGGESAL
Sbjct: 241 SGSTSFMKLNTSAGNVDIYKKLYHSDACSSKAVVSLRCIACGVNLNSSRQSRIVGGESAL 300
Query: 301 PGAWPWQVSLHVQNVHVCGGSIITPEWIVTAAHCVEKPLNNPWHWTAFAGILRQSFMFYG 360
PGAWPWQVSLHVQNVHVCGGSIITPEWIVTAAHCVEKPLNNPWHWTAFAGILRQSFMFYG
Sbjct: 301 PGAWPWQVSLHVQNVHVCGGSIITPEWIVTAAHCVEKPLNNPWHWTAFAGILRQSFMFYG 360
Query: 361 AGYQVEKVISHPNYDSKTKNNDIALMKLQKPLTFNDLVKPVCLPNPGMMLQPEQLCWISG 420
AGYQVEKVISHPNYDSKTKNNDIALMKLQKPLTFNDLVKPVCLPNPGMMLQPEQLCWISG
Sbjct: 361 AGYQVEKVISHPNYDSKTKNNDIALMKLQKPLTFNDLVKPVCLPNPGMMLQPEQLCWISG 420
Query: 421 WGATEEKGKTSEVLNAAKVLLIETQRCNSRYVYDNLITPAMICAGFLQGNVDSCQGDSGG 480
WGATEEKGKTSEVLNAAKVLLIETQRCNSRYVYDNLITPAMICAGFLQGNVDSCQGDSGG
Sbjct: 421 WGATEEKGKTSEVLNAAKVLLIETQRCNSRYVYDNLITPAMICAGFLQGNVDSCQGDSGG 480
Query: 481 PLVTSKNNIWWLIGDTSWGSGCAKAYRPGVYGNVMVFTDWIYRQMRADG 529
PLVTSKNNIWWLIGDTSWGSGCAKAYRPGVYGNVMVFTDWIYRQMRADG
Sbjct: 481 PLVTSKNNIWWLIGDTSWGSGCAKAYRPGVYGNVMVFTDWIYRQMRADG 529
>gi|205360943 transmembrane protease, serine 2 isoform 2 [Homo
sapiens]
Length = 492
Score = 1051 bits (2717), Expect = 0.0
Identities = 492/492 (100%), Positives = 492/492 (100%)
Query: 38 MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQA 97
MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQA
Sbjct: 1 MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQA 60
Query: 98 SNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIEC 157
SNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIEC
Sbjct: 61 SNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIEC 120
Query: 158 DSSGTCINPSNWCDGVSHCPGGEDENRCVRLYGPNFILQVYSSQRKSWHPVCQDDWNENY 217
DSSGTCINPSNWCDGVSHCPGGEDENRCVRLYGPNFILQVYSSQRKSWHPVCQDDWNENY
Sbjct: 121 DSSGTCINPSNWCDGVSHCPGGEDENRCVRLYGPNFILQVYSSQRKSWHPVCQDDWNENY 180
Query: 218 GRAACRDMGYKNNFYSSQGIVDDSGSTSFMKLNTSAGNVDIYKKLYHSDACSSKAVVSLR 277
GRAACRDMGYKNNFYSSQGIVDDSGSTSFMKLNTSAGNVDIYKKLYHSDACSSKAVVSLR
Sbjct: 181 GRAACRDMGYKNNFYSSQGIVDDSGSTSFMKLNTSAGNVDIYKKLYHSDACSSKAVVSLR 240
Query: 278 CIACGVNLNSSRQSRIVGGESALPGAWPWQVSLHVQNVHVCGGSIITPEWIVTAAHCVEK 337
CIACGVNLNSSRQSRIVGGESALPGAWPWQVSLHVQNVHVCGGSIITPEWIVTAAHCVEK
Sbjct: 241 CIACGVNLNSSRQSRIVGGESALPGAWPWQVSLHVQNVHVCGGSIITPEWIVTAAHCVEK 300
Query: 338 PLNNPWHWTAFAGILRQSFMFYGAGYQVEKVISHPNYDSKTKNNDIALMKLQKPLTFNDL 397
PLNNPWHWTAFAGILRQSFMFYGAGYQVEKVISHPNYDSKTKNNDIALMKLQKPLTFNDL
Sbjct: 301 PLNNPWHWTAFAGILRQSFMFYGAGYQVEKVISHPNYDSKTKNNDIALMKLQKPLTFNDL 360
Query: 398 VKPVCLPNPGMMLQPEQLCWISGWGATEEKGKTSEVLNAAKVLLIETQRCNSRYVYDNLI 457
VKPVCLPNPGMMLQPEQLCWISGWGATEEKGKTSEVLNAAKVLLIETQRCNSRYVYDNLI
Sbjct: 361 VKPVCLPNPGMMLQPEQLCWISGWGATEEKGKTSEVLNAAKVLLIETQRCNSRYVYDNLI 420
Query: 458 TPAMICAGFLQGNVDSCQGDSGGPLVTSKNNIWWLIGDTSWGSGCAKAYRPGVYGNVMVF 517
TPAMICAGFLQGNVDSCQGDSGGPLVTSKNNIWWLIGDTSWGSGCAKAYRPGVYGNVMVF
Sbjct: 421 TPAMICAGFLQGNVDSCQGDSGGPLVTSKNNIWWLIGDTSWGSGCAKAYRPGVYGNVMVF 480
Query: 518 TDWIYRQMRADG 529
TDWIYRQMRADG
Sbjct: 481 TDWIYRQMRADG 492
>gi|13173471 transmembrane protease, serine 3 isoform 1 [Homo
sapiens]
Length = 454
Score = 333 bits (854), Expect = 2e-91
Identities = 189/412 (45%), Positives = 242/412 (58%), Gaps = 21/412 (5%)
Query: 126 LTLGTFLVGAALAAGLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRC 185
+ +G + ALA GL F CS C SS CI CDGVS C GEDE RC
Sbjct: 52 IVIGIIALILALAIGLGIHF---DCSGK-YRCRSSFKCIELIARCDGVSDCKDGEDEYRC 107
Query: 186 VRLYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKNNFYSSQGIVDDSGSTS 245
VR+ G N +LQV+++ SW +C DDW +Y AC +G+ + + SS + S
Sbjct: 108 VRVGGQNAVLQVFTAA--SWKTMCSDDWKGHYANVACAQLGFPS-YVSSDNLRVSSLEGQ 164
Query: 246 FMKLNTSAGNV---DIYKKLYHS----DACSSKAVVSLRCIACGVNLNSSRQSRIVGGES 298
F + S ++ D L+HS + C+S VV+L+C ACG S SRIVGG
Sbjct: 165 FREEFVSIDHLLPDDKVTALHHSVYVREGCASGHVVTLQCTACGHRRGYS--SRIVGGNM 222
Query: 299 ALPGAWPWQVSLHVQNVHVCGGSIITPEWIVTAAHCVEKPLNNPWHWTAFAGILRQSFMF 358
+L WPWQ SL Q H+CGGS+ITP WI+TAAHCV L P WT G++ S +
Sbjct: 223 SLLSQWPWQASLQFQGYHLCGGSVITPLWIITAAHCVYD-LYLPKSWTIQVGLV--SLLD 279
Query: 359 YGA-GYQVEKVISHPNYDSKTKNNDIALMKLQKPLTFNDLVKPVCLPNPGMMLQPEQLCW 417
A + VEK++ H Y K NDIALMKL PLTFN++++PVCLPN ++CW
Sbjct: 280 NPAPSHLVEKIVYHSKYKPKRLGNDIALMKLAGPLTFNEMIQPVCLPNSEENFPDGKVCW 339
Query: 418 ISGWGATEE-KGKTSEVLNAAKVLLIETQRCNSRYVYDNLITPAMICAGFLQGNVDSCQG 476
SGWGATE+ G S VLN A V LI + CN R VY +I+P+M+CAG+L G VDSCQG
Sbjct: 340 TSGWGATEDGAGDASPVLNHAAVPLISNKICNHRDVYGGIISPSMLCAGYLTGGVDSCQG 399
Query: 477 DSGGPLVTSKNNIWWLIGDTSWGSGCAKAYRPGVYGNVMVFTDWIYRQMRAD 528
DSGGPLV + +W L+G TS+G GCA+ +PGVY V F DWI+ QM D
Sbjct: 400 DSGGPLVCQERRLWKLVGATSFGIGCAEVNKPGVYTRVTSFLDWIHEQMERD 451
>gi|116256363 transmembrane protease, serine 13 [Homo sapiens]
Length = 567
Score = 277 bits (709), Expect = 2e-74
Identities = 162/462 (35%), Positives = 241/462 (52%), Gaps = 32/462 (6%)
Query: 84 SPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLT----------LGTFLV 133
SP Y R + P+ + +S T T ++ T +G L+
Sbjct: 115 SPTRVYLVRATPVGAVPIRSSPARSAPATRATRESPGTSLPKFTWREGQKQLPLIGCVLL 174
Query: 134 GAALAAGLLWKFMGSKCSNSGIEC-DSSGTCINPSNWCDGVSHCPGGEDENRCVRLYGPN 192
AL L+ F + ++GI + +C + CDGV C DE CVR
Sbjct: 175 LIALVVSLIILFQFWQ-GHTGIRYKEQRESCPKHAVRCDGVVDCKLKSDELGCVRFDWDK 233
Query: 193 FILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKNNFYSSQGIVDD-SGSTSFMKLNT 251
+L++YS W P+C +WN++Y C+ +G+++ +++ D + S S ++ N+
Sbjct: 234 SLLKIYSGSSHQWLPICSSNWNDSYSEKTCQQLGFESAHRTTEVAHRDFANSFSILRYNS 293
Query: 252 SAGNVDIYKKLYHSDACSSKAVVSLRCIACGVNLNSSRQSRIVGGESALPGAWPWQVSLH 311
+ I + L+ S+ C S+ +SL+C CG+ + RIVGG A WPWQVSLH
Sbjct: 294 T-----IQESLHRSE-CPSQRYISLQCSHCGLR---AMTGRIVGGALASDSKWPWQVSLH 344
Query: 312 VQNVHVCGGSIITPEWIVTAAHCV----EKPLNNPWHWTAFAGILRQSFMFYGAGYQVEK 367
H+CGG++I +W++TAAHC EK L W +AG + A + +
Sbjct: 345 FGTTHICGGTLIDAQWVLTAAHCFFVTREKVLEG---WKVYAGTSNLHQLPEAAS--IAE 399
Query: 368 VISHPNYDSKTKNNDIALMKLQKPLTFNDLVKPVCLPNPGMMLQPEQLCWISGWGATEEK 427
+I + NY + + DIALM+L KPLT + + P CLP G + CWI+G+G T E
Sbjct: 400 IIINSNYTDEEDDYDIALMRLSKPLTLSAHIHPACLPMHGQTFSLNETCWITGFGKTRET 459
Query: 428 G-KTSEVLNAAKVLLIETQRCNSRYVYDNLITPAMICAGFLQGNVDSCQGDSGGPLVTSK 486
KTS L +V LI+ ++CN VYD+ +TP M+CAG L+G DSCQGDSGGPLV +
Sbjct: 460 DDKTSPFLREVQVNLIDFKKCNDYLVYDSYLTPRMMCAGDLRGGRDSCQGDSGGPLVCEQ 519
Query: 487 NNIWWLIGDTSWGSGCAKAYRPGVYGNVMVFTDWIYRQMRAD 528
NN W+L G TSWG+GC + +PGVY V WIY +M ++
Sbjct: 520 NNRWYLAGVTSWGTGCGQRNKPGVYTKVTEVLPWIYSKMESE 561
>gi|145701030 transmembrane protease, serine 4 isoform 3 [Homo
sapiens]
Length = 432
Score = 252 bits (644), Expect = 5e-67
Identities = 144/375 (38%), Positives = 201/375 (53%), Gaps = 36/375 (9%)
Query: 170 CDGVSHCPGGEDENRCVRLY--GP---------NFILQVYSSQRKSWHPVCQDDWNENYG 218
CDG CP GEDE CV+ + GP LQV S +W C D++ E
Sbjct: 77 CDGELDCPLGEDEEHCVKSFPEGPAVAVRLSKDRSTLQVLDSATGNWFSACFDNFTEALA 136
Query: 219 RAACRDMGYKNNFY----SSQGIVDDSGSTSFMKLNTSAGNVDIYKKLYHSDACSSKAVV 274
ACR MGY +V+ + ++ +++ S+G C S ++V
Sbjct: 137 ETACRQMGYSRAVEIGPDQDLDVVEITENSQELRMRNSSG------------PCLSGSLV 184
Query: 275 SLRCIACGVNLNSSRQSRIVGGESALPGAWPWQVSLHVQNVHVCGGSIITPEWIVTAAHC 334
SL C+ACG +L + R +VGGE A +WPWQVS+ HVCGGSI+ P W++TAAHC
Sbjct: 185 SLHCLACGKSLKTPR---VVGGEEASVDSWPWQVSIQYDKQHVCGGSILDPHWVLTAAHC 241
Query: 335 VEKPLNNPWHWTAFAGILRQSFMFYGAGYQVEKVISHPNYDSKTKNNDIALMKLQKPLTF 394
K + ++W AG + A ++ + +P Y K+NDIALMKLQ PLTF
Sbjct: 242 FRKH-TDVFNWKVRAGSDKLGSFPSLAVAKIIIIEFNPMY---PKDNDIALMKLQFPLTF 297
Query: 395 NDLVKPVCLPNPGMMLQPEQLCWISGWGATEEK-GKTSEVLNAAKVLLIETQRCNSRYVY 453
+ V+P+CLP L P WI GWG T++ GK S++L A V +I++ RCN+ Y
Sbjct: 298 SGTVRPICLPFFDEELTPATPLWIIGWGFTKQNGGKMSDILLQASVQVIDSTRCNADDAY 357
Query: 454 DNLITPAMICAGFLQGNVDSCQGDSGGPLVTSKNNIWWLIGDTSWGSGCAKAYRPGVYGN 513
+T M+CAG +G VD+CQGDSGGPL+ + W ++G SWG GC PGVY
Sbjct: 358 QGEVTEKMMCAGIPEGGVDTCQGDSGGPLMYQSDQ-WHVVGIVSWGYGCGGPSTPGVYTK 416
Query: 514 VMVFTDWIYRQMRAD 528
V + +WIY +A+
Sbjct: 417 VSAYLNWIYNVWKAE 431
>gi|15451940 transmembrane protease, serine 4 isoform 1 [Homo
sapiens]
Length = 437
Score = 252 bits (643), Expect = 7e-67
Identities = 146/380 (38%), Positives = 205/380 (53%), Gaps = 41/380 (10%)
Query: 170 CDGVSHCPGGEDENRCVRLY--GP---------NFILQVYSSQRKSWHPVCQDDWNENYG 218
CDG CP GEDE CV+ + GP LQV S +W C D++ E
Sbjct: 77 CDGELDCPLGEDEEHCVKSFPEGPAVAVRLSKDRSTLQVLDSATGNWFSACFDNFTEALA 136
Query: 219 RAACRDMGY--KNNFYSSQ-------GIVDDSGSTSFMKLNTSAGNVDIYKKLYHSDACS 269
ACR MGY K F + + +V+ + ++ +++ S+G C
Sbjct: 137 ETACRQMGYSSKPTFRAVEIGPDQDLDVVEITENSQELRMRNSSG------------PCL 184
Query: 270 SKAVVSLRCIACGVNLNSSRQSRIVGGESALPGAWPWQVSLHVQNVHVCGGSIITPEWIV 329
S ++VSL C+ACG +L + R +VGGE A +WPWQVS+ HVCGGSI+ P W++
Sbjct: 185 SGSLVSLHCLACGKSLKTPR---VVGGEEASVDSWPWQVSIQYDKQHVCGGSILDPHWVL 241
Query: 330 TAAHCVEKPLNNPWHWTAFAGILRQSFMFYGAGYQVEKVISHPNYDSKTKNNDIALMKLQ 389
TAAHC K + ++W AG + A ++ + +P Y K+NDIALMKLQ
Sbjct: 242 TAAHCFRKH-TDVFNWKVRAGSDKLGSFPSLAVAKIIIIEFNPMY---PKDNDIALMKLQ 297
Query: 390 KPLTFNDLVKPVCLPNPGMMLQPEQLCWISGWGATEEK-GKTSEVLNAAKVLLIETQRCN 448
PLTF+ V+P+CLP L P WI GWG T++ GK S++L A V +I++ RCN
Sbjct: 298 FPLTFSGTVRPICLPFFDEELTPATPLWIIGWGFTKQNGGKMSDILLQASVQVIDSTRCN 357
Query: 449 SRYVYDNLITPAMICAGFLQGNVDSCQGDSGGPLVTSKNNIWWLIGDTSWGSGCAKAYRP 508
+ Y +T M+CAG +G VD+CQGDSGGPL+ + W ++G SWG GC P
Sbjct: 358 ADDAYQGEVTEKMMCAGIPEGGVDTCQGDSGGPLMYQSDQ-WHVVGIVSWGYGCGGPSTP 416
Query: 509 GVYGNVMVFTDWIYRQMRAD 528
GVY V + +WIY +A+
Sbjct: 417 GVYTKVSAYLNWIYNVWKAE 436
>gi|170932492 transmembrane protease, serine 5 [Homo sapiens]
Length = 457
Score = 249 bits (635), Expect = 6e-66
Identities = 132/341 (38%), Positives = 181/341 (53%), Gaps = 9/341 (2%)
Query: 187 RLYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKNNFYSSQGIVDD---SGS 243
R+ +F+L+ + W VC + W+ G C +G+ + + D + S
Sbjct: 113 RINSEDFLLEAQVRDQPRWLLVCHEGWSPALGLQICWSLGHLRLTHHKGVNLTDIKLNSS 172
Query: 244 TSFMKLNTSAGNVDIYKKLYHSDACSSKAVVSLRCIACGVNLNSSRQSRIVGGESALPGA 303
F +L+ G + + + C+S VVSLRC CG SRIVGG+S PG
Sbjct: 173 QEFAQLSPRLGGF-LEEAWQPRNNCTSGQVVSLRCSECGAR---PLASRIVGGQSVAPGR 228
Query: 304 WPWQVSLHVQNVHVCGGSIITPEWIVTAAHCVEK-PLNNPWHWTAFAGILRQSFMFYGAG 362
WPWQ S+ + H CGGS++ P W+VTAAHC+ L W AG++ S + G
Sbjct: 229 WPWQASVALGFRHTCGGSVLAPRWVVTAAHCMHSFRLARLSSWRVHAGLVSHSAVRPHQG 288
Query: 363 YQVEKVISHPNYDSKTKNNDIALMKLQKPLTFNDLVKPVCLPNPGMMLQPEQLCWISGWG 422
VE++I HP Y ++ + D+AL++LQ L F+D V VCLP CW+SGWG
Sbjct: 289 ALVERIIPHPLYSAQNHDYDVALLRLQTALNFSDTVGAVCLPAKEQHFPKGSRCWVSGWG 348
Query: 423 ATEEKGK-TSEVLNAAKVLLIETQRCNSRYVYDNLITPAMICAGFLQGNVDSCQGDSGGP 481
T +S++L V L TQ CNS VY +TP M+CAG+L G D+CQGDSGGP
Sbjct: 349 HTHPSHTYSSDMLQDTVVPLFSTQLCNSSCVYSGALTPRMLCAGYLDGRADACQGDSGGP 408
Query: 482 LVTSKNNIWWLIGDTSWGSGCAKAYRPGVYGNVMVFTDWIY 522
LV + W L+G SWG GCA+ PGVY V F DWI+
Sbjct: 409 LVCPDGDTWRLVGVVSWGRGCAEPNHPGVYAKVAEFLDWIH 449
>gi|223942069 enterokinase precursor [Homo sapiens]
Length = 1019
Score = 247 bits (630), Expect = 2e-65
Identities = 137/379 (36%), Positives = 204/379 (53%), Gaps = 14/379 (3%)
Query: 150 CSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVRLYG--PNFILQVYSSQRKSWHP 207
C +C +G C+ N CDG HC G DE CVR + N V + WH
Sbjct: 643 CKADHFQC-KNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHT 701
Query: 208 VCQDDWNENYGRAACRDMGYKNNFYSSQGIVDDSGSTSFMKLNTSAGNVDIYKKLYHSDA 267
C ++W C+ +G + S D G F+KLNT+ D + L S
Sbjct: 702 ACAENWTTQISNDVCQLLGLGSGNSSKPIFSTDGGP--FVKLNTAP---DGHLILTPSQQ 756
Query: 268 CSSKAVVSLRCI--ACGVNLNSSRQS-RIVGGESALPGAWPWQVSLHVQNVHVCGGSIIT 324
C +++ L+C +CG L + + +IVGG +A GAWPW V L+ +CG S+++
Sbjct: 757 CLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVS 816
Query: 325 PEWIVTAAHCVEKPLNNPWHWTAFAGILRQSFMFYGAGYQ--VEKVISHPNYDSKTKNND 382
+W+V+AAHCV P WTA G+ +S + +++++ +P+Y+ + K+ND
Sbjct: 817 SDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDND 876
Query: 383 IALMKLQKPLTFNDLVKPVCLPNPGMMLQPEQLCWISGWGATEEKGKTSEVLNAAKVLLI 442
IA+M L+ + + D ++P+CLP + P + C I+GWG +G T+ +L A V L+
Sbjct: 877 IAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLL 936
Query: 443 ETQRCNSRYVYDNLITPAMICAGFLQGNVDSCQGDSGGPLVTSKNNIWWLIGDTSWGSGC 502
+RC + N IT MICAG+ +G +DSCQGDSGGPL+ +NN W+L G TS+G C
Sbjct: 937 SNERCQQQMPEYN-ITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKC 995
Query: 503 AKAYRPGVYGNVMVFTDWI 521
A RPGVY V FT+WI
Sbjct: 996 ALPNRPGVYARVSRFTEWI 1014
Score = 37.7 bits (86), Expect = 0.026
Identities = 31/125 (24%), Positives = 51/125 (40%), Gaps = 14/125 (11%)
Query: 149 KCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENR--CVRLYGPNFILQVYSSQRKSWH 206
+C C + TCI +CDG +CP G DE+ C + F+L S ++ H
Sbjct: 183 ECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATH 242
Query: 207 --------PVCQDDWNENYGRAACRDMGYKNNFYSS-QGIVDDSGSTSFMKLN---TSAG 254
VCQ N G + N +Y+ I + GS+ ++ + T+ G
Sbjct: 243 YPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPG 302
Query: 255 NVDIY 259
+ I+
Sbjct: 303 TIRIF 307
>gi|29244926 corin [Homo sapiens]
Length = 1042
Score = 226 bits (576), Expect = 4e-59
Identities = 138/391 (35%), Positives = 200/391 (51%), Gaps = 22/391 (5%)
Query: 148 SKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVRL---YGPNFILQVYSSQRKS 204
S C + +EC ++ C++ WCDG + C DE CV L + L V+ + +
Sbjct: 653 SFCQDDELEC-ANHACVSRDLWCDGEADCSDSSDEWDCVTLSINVNSSSFLMVHRAATE- 710
Query: 205 WHPVCQDDWNENYGRAACRDMGYKNNFYSSQGIVDDSGSTSFMKLNT---SAGNVDIYKK 261
H VC D W E + AC+ MG + I + ++ L++ S +++
Sbjct: 711 -HHVCADGWQEILSQLACKQMGLGEPSVTKL-IQEQEKEPRWLTLHSNWESLNGTTLHEL 768
Query: 262 LYHSDACSSKAVVSLRCIA--CGVNLNSSRQSRIVGGESALPGAWPWQVSLHVQ-NVHVC 318
L + +C S++ +SL C CG + RI+GG ++ PG WPWQ SL + + H+C
Sbjct: 769 LVNGQSCESRSKISLLCTKQDCGRRPAARMNKRILGGRTSRPGRWPWQCSLQSEPSGHIC 828
Query: 319 GGSIITPEWIVTAAHCVEKPLNNPWHWTAFAGI--LRQSFMFYGAGYQVEKVISHPNYDS 376
G +I +W++T AHC E N W GI L +F + V+ +I HP Y
Sbjct: 829 GCVLIAKKWVLTVAHCFEGR-ENAAVWKVVLGINNLDHPSVFMQTRF-VKTIILHPRYSR 886
Query: 377 KTKNNDIALMKLQKPLTFNDLVKPVCLPNPGMMLQPEQLCWISGWGATEEKGKTSEVLNA 436
+ DI++++L + ++ V+PVCLPNP L+P+ C+I+GWG K L
Sbjct: 887 AVVDYDISIVELSEDISETGYVRPVCLPNPEQWLEPDTYCYITGWG--HMGNKMPFKLQE 944
Query: 437 AKVLLIETQRCNSRYVYDNLITPAMICAGFLQGNVDSCQGDSGGPLVTSK-NNIWWLIGD 495
+V +I + C S Y IT MICAG+ G VDSC GDSGGPLV K W L G
Sbjct: 945 GEVRIISLEHCQS-YFDMKTITTRMICAGYESGTVDSCMGDSGGPLVCEKPGGRWTLFGL 1003
Query: 496 TSWGSGC-AKAYRPGVYGNVMVFTDWIYRQM 525
TSWGS C +K PGVY NV F +WI RQ+
Sbjct: 1004 TSWGSVCFSKVLGPGVYSNVSYFVEWIKRQI 1034
Score = 33.1 bits (74), Expect = 0.64
Identities = 15/37 (40%), Positives = 19/37 (51%), Gaps = 1/37 (2%)
Query: 149 KCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRC 185
+CS S +C SG C+ S CDG + C DE C
Sbjct: 579 ECSPSHFKC-RSGQCVLASRRCDGQADCDDDSDEENC 614
Score = 31.2 bits (69), Expect = 2.5
Identities = 13/36 (36%), Positives = 17/36 (47%)
Query: 150 CSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRC 185
C + G+ +G CI + CDG C G DE C
Sbjct: 379 CHSQGLVECRNGQCIPSTFQCDGDEDCKDGSDEENC 414
Score = 29.6 bits (65), Expect = 7.1
Identities = 14/36 (38%), Positives = 17/36 (47%), Gaps = 1/36 (2%)
Query: 150 CSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRC 185
CS + C + G C+N S CDG C DE C
Sbjct: 306 CSENLFHCHT-GKCLNYSLVCDGYDDCGDLSDEQNC 340
>gi|78191798 plasma kallikrein B1 precursor [Homo sapiens]
Length = 638
Score = 217 bits (552), Expect = 2e-56
Identities = 109/260 (41%), Positives = 157/260 (60%), Gaps = 10/260 (3%)
Query: 275 SLRCIACGVN--LNSSRQSRIVGGESALPGAWPWQVSLHVQNV---HVCGGSIITPEWIV 329
SLR G N + +RIVGG ++ G WPWQVSL V+ H+CGGS+I +W++
Sbjct: 371 SLRLCNTGDNSVCTTKTSTRIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVL 430
Query: 330 TAAHCVEK-PLNNPWHWTAFAGILRQSFMFYGAGY-QVEKVISHPNYDSKTKNNDIALMK 387
TAAHC + PL + W ++GIL S + + Q++++I H NY N+DIAL+K
Sbjct: 431 TAAHCFDGLPLQDVWR--IYSGILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIK 488
Query: 388 LQKPLTFNDLVKPVCLPNPGMMLQPEQLCWISGWGATEEKGKTSEVLNAAKVLLIETQRC 447
LQ PL + + KP+CLP+ G CW++GWG ++EKG+ +L + L+ + C
Sbjct: 489 LQAPLNYTEFQKPICLPSKGDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEEC 548
Query: 448 NSRYVYDNLITPAMICAGFLQGNVDSCQGDSGGPLVTSKNNIWWLIGDTSWGSGCAKAYR 507
RY D IT M+CAG+ +G D+C+GDSGGPLV N +W L+G TSWG GCA+ +
Sbjct: 549 QKRY-QDYKITQRMVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQ 607
Query: 508 PGVYGNVMVFTDWIYRQMRA 527
PGVY V + DWI + ++
Sbjct: 608 PGVYTKVAEYMDWILEKTQS 627
>gi|33695155 hepsin [Homo sapiens]
Length = 417
Score = 211 bits (537), Expect = 1e-54
Identities = 118/346 (34%), Positives = 174/346 (50%), Gaps = 17/346 (4%)
Query: 195 LQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKNNFYSSQGIVDDSGSTSFMKLN-TSA 253
L V+ +W +C N +C +MG+ S+ V +G+
Sbjct: 63 LMVFDKTEGTWRLLCSSRSNARVAGLSCEEMGFLRALTHSELDVRTAGANGTSGFFCVDE 122
Query: 254 GNVDIYKKLYHSDA---CSSKAVVSLRCIACGVNLNSSRQSRIVGGESALPGAWPWQVSL 310
G + ++L + C ++ C CG RIVGG G WPWQVSL
Sbjct: 123 GRLPHTQRLLEVISVCDCPRGRFLAAICQDCG--RRKLPVDRIVGGRDTSLGRWPWQVSL 180
Query: 311 HVQNVHVCGGSIITPEWIVTAAHCVEKPLNNPWHWTAFAGILRQSFMFYGAGYQVEKVIS 370
H+CGGS+++ +W++TAAHC + W FAG + Q+ +G V+ V+
Sbjct: 181 RYDGAHLCGGSLLSGDWVLTAAHCFPERNRVLSRWRVFAGAVAQASP-HGLQLGVQAVVY 239
Query: 371 HPNY------DSKTKNNDIALMKLQKPLTFNDLVKPVCLPNPGMMLQPEQLCWISGWGAT 424
H Y +S+ +NDIAL+ L PL + ++PVCLP G L ++C ++GWG T
Sbjct: 240 HGGYLPFRDPNSEENSNDIALVHLSSPLPLTEYIQPVCLPAAGQALVDGKICTVTGWGNT 299
Query: 425 EEKGKTSEVLNAAKVLLIETQRCNSRYVYDNLITPAMICAGFLQGNVDSCQGDSGGPLV- 483
+ G+ + VL A+V +I CN Y N I P M CAG+ +G +D+CQGDSGGP V
Sbjct: 300 QYYGQQAGVLQEARVPIISNDVCNGADFYGNQIKPKMFCAGYPEGGIDACQGDSGGPFVC 359
Query: 484 ---TSKNNIWWLIGDTSWGSGCAKAYRPGVYGNVMVFTDWIYRQMR 526
S+ W L G SWG+GCA A +PGVY V F +WI++ ++
Sbjct: 360 EDSISRTPRWRLCGIVSWGTGCALAQKPGVYTKVSDFREWIFQAIK 405
>gi|4504481 hepsin [Homo sapiens]
Length = 417
Score = 211 bits (537), Expect = 1e-54
Identities = 118/346 (34%), Positives = 174/346 (50%), Gaps = 17/346 (4%)
Query: 195 LQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKNNFYSSQGIVDDSGSTSFMKLN-TSA 253
L V+ +W +C N +C +MG+ S+ V +G+
Sbjct: 63 LMVFDKTEGTWRLLCSSRSNARVAGLSCEEMGFLRALTHSELDVRTAGANGTSGFFCVDE 122
Query: 254 GNVDIYKKLYHSDA---CSSKAVVSLRCIACGVNLNSSRQSRIVGGESALPGAWPWQVSL 310
G + ++L + C ++ C CG RIVGG G WPWQVSL
Sbjct: 123 GRLPHTQRLLEVISVCDCPRGRFLAAICQDCG--RRKLPVDRIVGGRDTSLGRWPWQVSL 180
Query: 311 HVQNVHVCGGSIITPEWIVTAAHCVEKPLNNPWHWTAFAGILRQSFMFYGAGYQVEKVIS 370
H+CGGS+++ +W++TAAHC + W FAG + Q+ +G V+ V+
Sbjct: 181 RYDGAHLCGGSLLSGDWVLTAAHCFPERNRVLSRWRVFAGAVAQASP-HGLQLGVQAVVY 239
Query: 371 HPNY------DSKTKNNDIALMKLQKPLTFNDLVKPVCLPNPGMMLQPEQLCWISGWGAT 424
H Y +S+ +NDIAL+ L PL + ++PVCLP G L ++C ++GWG T
Sbjct: 240 HGGYLPFRDPNSEENSNDIALVHLSSPLPLTEYIQPVCLPAAGQALVDGKICTVTGWGNT 299
Query: 425 EEKGKTSEVLNAAKVLLIETQRCNSRYVYDNLITPAMICAGFLQGNVDSCQGDSGGPLV- 483
+ G+ + VL A+V +I CN Y N I P M CAG+ +G +D+CQGDSGGP V
Sbjct: 300 QYYGQQAGVLQEARVPIISNDVCNGADFYGNQIKPKMFCAGYPEGGIDACQGDSGGPFVC 359
Query: 484 ---TSKNNIWWLIGDTSWGSGCAKAYRPGVYGNVMVFTDWIYRQMR 526
S+ W L G SWG+GCA A +PGVY V F +WI++ ++
Sbjct: 360 EDSISRTPRWRLCGIVSWGTGCALAQKPGVYTKVSDFREWIFQAIK 405
>gi|194018492 transmembrane protease, serine 11F [Homo sapiens]
Length = 438
Score = 208 bits (530), Expect = 9e-54
Identities = 110/286 (38%), Positives = 161/286 (56%), Gaps = 14/286 (4%)
Query: 246 FMKLNTSAGNVDIYKKLYHSDACSSKAVVSLRCIACGVNLNSSRQ--------SRIVGG- 296
+ L T ++ I K + SK + +L CG+ + SS RIV G
Sbjct: 151 YQSLKTKQLSLTINKPSFRLTPIDSKKMRNLLNSRCGIRMTSSNMPLPASSSTQRIVQGR 210
Query: 297 ESALPGAWPWQVSLH-VQNVHVCGGSIITPEWIVTAAHCVEKPLNNPWHWTAFAGILRQS 355
E+A+ G WPWQ SL + + H CG S+I+ W++TAAHC K +P W A G +
Sbjct: 211 ETAMEGEWPWQASLQLIGSGHQCGASLISNTWLLTAAHCFWKN-KDPTQWIATFGA---T 266
Query: 356 FMFYGAGYQVEKVISHPNYDSKTKNNDIALMKLQKPLTFNDLVKPVCLPNPGMMLQPEQL 415
V K+I H NY +T NDIAL++L + F+++V+ VCLP+ + L P+
Sbjct: 267 ITPPAVKRNVRKIILHENYHRETNENDIALVQLSTGVEFSNIVQRVCLPDSSIKLPPKTS 326
Query: 416 CWISGWGATEEKGKTSEVLNAAKVLLIETQRCNSRYVYDNLITPAMICAGFLQGNVDSCQ 475
+++G+G+ + G L A+V I T CN + VYD LITP M+CAGF++G +D+C+
Sbjct: 327 VFVTGFGSIVDDGPIQNTLRQARVETISTDVCNRKDVYDGLITPGMLCAGFMEGKIDACK 386
Query: 476 GDSGGPLVTSKNNIWWLIGDTSWGSGCAKAYRPGVYGNVMVFTDWI 521
GDSGGPLV ++IW+++G SWG CA +PGVY V + DWI
Sbjct: 387 GDSGGPLVYDNHDIWYIVGIVSWGQSCALPKKPGVYTRVTKYRDWI 432
>gi|4758508 transmembrane protease, serine 11D [Homo sapiens]
Length = 418
Score = 204 bits (519), Expect = 2e-52
Identities = 103/244 (42%), Positives = 139/244 (56%), Gaps = 5/244 (2%)
Query: 282 GVNLNSSRQSRIVGGESALPGAWPWQVSLHVQNVHVCGGSIITPEWIVTAAHCVEKPLNN 341
G +L + + RI+GG A G+WPWQVSL + N H CGGS+I WI+TAAHC +N
Sbjct: 176 GPDLITLSEQRILGGTEAEEGSWPWQVSLRLNNAHHCGGSLINNMWILTAAHCFRSN-SN 234
Query: 342 PWHWTAFAGILRQSFMFYGAGYQVEKVISHPNYDSKTKNNDIALMKLQKPLTFNDLVKPV 401
P W A +GI S F +V ++ H NY S T NDIAL++L+ +TF + V
Sbjct: 235 PRDWIATSGI---STTFPKLRMRVRNILIHNNYKSATHENDIALVRLENSVTFTKDIHSV 291
Query: 402 CLPNPGMMLQPEQLCWISGWGATEEKGKTSEVLNAAKVLLIETQRCNSRYVYDNLITPAM 461
CLP + P +++GWGA E G T L +V +I CN+ + Y+ I M
Sbjct: 292 CLPAATQNIPPGSTAYVTGWGAQEYAGHTVPELRQGQVRIISNDVCNAPHSYNGAILSGM 351
Query: 462 ICAGFLQGNVDSCQGDSGGPLV-TSKNNIWWLIGDTSWGSGCAKAYRPGVYGNVMVFTDW 520
+CAG QG VD+CQGDSGGPLV +W+++G SWG C +PGVY V + DW
Sbjct: 352 LCAGVPQGGVDACQGDSGGPLVQEDSRRLWFIVGIVSWGDQCGLPDKPGVYTRVTAYLDW 411
Query: 521 IYRQ 524
I +Q
Sbjct: 412 IRQQ 415
>gi|4503627 coagulation factor XI precursor [Homo sapiens]
Length = 625
Score = 203 bits (517), Expect = 3e-52
Identities = 103/244 (42%), Positives = 146/244 (59%), Gaps = 14/244 (5%)
Query: 292 RIVGGESALPGAWPWQVSLHVQNV---HVCGGSIITPEWIVTAAHCVEKPLNNPWHWTAF 348
RIVGG +++ G WPWQV+LH + H+CGGSII +WI+TAAHC + +P +
Sbjct: 387 RIVGGTASVRGEWPWQVTLHTTSPTQRHLCGGSIIGNQWILTAAHCFYG-VESPKILRVY 445
Query: 349 AGILRQSFM-----FYGAGYQVEKVISHPNYDSKTKNNDIALMKLQKPLTFNDLVKPVCL 403
+GIL QS + F+G V+++I H Y DIAL+KL+ + + D +P+CL
Sbjct: 446 SGILNQSEIKEDTSFFG----VQEIIIHDQYKMAESGYDIALLKLETTVNYTDSQRPICL 501
Query: 404 PNPGMMLQPEQLCWISGWGATEEKGKTSEVLNAAKVLLIETQRCNSRYVYDNLITPAMIC 463
P+ G CW++GWG + + K L AK+ L+ + C RY + IT MIC
Sbjct: 502 PSKGDRNVIYTDCWVTGWGYRKLRDKIQNTLQKAKIPLVTNEECQKRY-RGHKITHKMIC 560
Query: 464 AGFLQGNVDSCQGDSGGPLVTSKNNIWWLIGDTSWGSGCAKAYRPGVYGNVMVFTDWIYR 523
AG+ +G D+C+GDSGGPL N +W L+G TSWG GCA+ RPGVY NV+ + DWI
Sbjct: 561 AGYREGGKDACKGDSGGPLSCKHNEVWHLVGITSWGEGCAQRERPGVYTNVVEYVDWILE 620
Query: 524 QMRA 527
+ +A
Sbjct: 621 KTQA 624
>gi|11415040 matriptase [Homo sapiens]
Length = 855
Score = 202 bits (515), Expect = 5e-52
Identities = 132/397 (33%), Positives = 190/397 (47%), Gaps = 43/397 (10%)
Query: 160 SGTCINPSNWCDGVSHCPGGEDENRCVRLYGPNFILQVYSSQRKSWHPVCQDDWNENYGR 219
+G CI CDG + C DE C G F + + W +D +N
Sbjct: 461 TGRCIRKELRCDGWADCTDHSDELNCSCDAGHQFTCKNKFCKPLFWVCDSVNDCGDNSDE 520
Query: 220 AAC------------RDMGYKNNFYSSQGIVDDSGSTSFMKLNTSAGNVDIYKKLYHSDA 267
C + + D S S K+N Y+ L +
Sbjct: 521 QGCSCPAQTFRCSNGKCLSKSQQCNGKDDCGDGSDEASCPKVNVVTCTKHTYRCL--NGL 578
Query: 268 CSSKAVVSLRCIA------------CGVNLNS-SRQSRIVGGESALPGAWPWQVSLHVQN 314
C SK + C C L S +RQ+R+VGG A G WPWQVSLH
Sbjct: 579 CLSKG--NPECDGKEDCSDGSDEKDCDCGLRSFTRQARVVGGTDADEGEWPWQVSLHALG 636
Query: 315 V-HVCGGSIITPEWIVTAAHCVEKP----LNNPWHWTAFAGILRQSFMFYGAGYQ---VE 366
H+CG S+I+P W+V+AAHC ++P WTAF G+ QS G Q ++
Sbjct: 637 QGHICGASLISPNWLVSAAHCYIDDRGFRYSDPTQWTAFLGLHDQS-QRSAPGVQERRLK 695
Query: 367 KVISHPNYDSKTKNNDIALMKLQKPLTFNDLVKPVCLPNPGMMLQPEQLCWISGWGATEE 426
++ISHP ++ T + DIAL++L+KP ++ +V+P+CLP+ + + W++GWG T+
Sbjct: 696 RIISHPFFNDFTFDYDIALLELEKPAEYSSMVRPICLPDASHVFPAGKAIWVTGWGHTQY 755
Query: 427 KGKTSEVLNAAKVLLIETQRCNSRYVYDNLITPAMICAGFLQGNVDSCQGDSGGPL--VT 484
G + +L ++ +I C + + ITP M+C GFL G VDSCQGDSGGPL V
Sbjct: 756 GGTGALILQKGEIRVINQTTCEN--LLPQQITPRMMCVGFLSGGVDSCQGDSGGPLSSVE 813
Query: 485 SKNNIWWLIGDTSWGSGCAKAYRPGVYGNVMVFTDWI 521
+ I + G SWG GCA+ +PGVY + +F DWI
Sbjct: 814 ADGRI-FQAGVVSWGDGCAQRNKPGVYTRLPLFRDWI 849
>gi|222831592 transmembrane protease, serine 7 [Homo sapiens]
Length = 717
Score = 194 bits (494), Expect = 1e-49
Identities = 128/389 (32%), Positives = 184/389 (47%), Gaps = 50/389 (12%)
Query: 150 CSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVRLYGPNFILQVYSSQRKSWHPVC 209
C C SSG C+ + CDGV+ C DE CV S P C
Sbjct: 358 CPVGSFRC-SSGLCVPQAQRCDGVNDCFDESDELFCV-----------------SPQPAC 399
Query: 210 QDDWNENYGRAACRDMGYKNNFYSSQGIVDDSGSTSFMKLNT---SAGNVDIYKKLYHSD 266
+G C + F + D+ T + N GN ++K
Sbjct: 400 NTSSFRQHGPLIC------DGFRDCENGRDEQNCTQSIPCNNRTFKCGNDICFRKQ---- 449
Query: 267 ACSSKAVVSLRCI------ACGVNLNSSRQSRIVGGESALPGAWPWQVSLHVQNVHVCGG 320
++K ++ C C + +SS RI+GG L G WPWQVSLH CG
Sbjct: 450 --NAKCDGTVDCPDGSDEEGCTCSRSSSALHRIIGGTDTLEGGWPWQVSLHFVGSAYCGA 507
Query: 321 SIITPEWIVTAAHCVE-KPLNNPWHWTAFAGILRQSFMFYGAGYQVEKVISHPNYDSKTK 379
S+I+ EW+++AAHC L++P WTA G+ Q + + V +++ H Y+S+T
Sbjct: 508 SVISREWLLSAAHCFHGNRLSDPTPWTAHLGMYVQGNAKFVS--PVRRIVVHEYYNSQTF 565
Query: 380 NNDIALMKLQ--KPLTFNDLVKPVCLPNPGMMLQPEQLCWISGWGATEE-KGKTSEVLNA 436
+ DIAL++L P T L++P+C+P G ++ + CW++GWG E K S VL
Sbjct: 566 DYDIALLQLSIAWPETLKQLIQPICIPPTGQRVRSGEKCWVTGWGRRHEADNKGSLVLQQ 625
Query: 437 AKVLLIETQRCNSRYVYDNLITPAMICAGFLQGNVDSCQGDSGGPLVTSK--NNIWWLIG 494
A+V LI+ C S Y +IT M+CAG + G D+C+GDSGGPL + + W L G
Sbjct: 626 AEVELIDQTLCVSTY---GIITSRMLCAGIMSGKRDACKGDSGGPLSCRRKSDGKWILTG 682
Query: 495 DTSWGSGCAKAYRPGVYGNVMVFTDWIYR 523
SWG G + PGVY V F WI++
Sbjct: 683 IVSWGHGSGRPNFPGVYTRVSNFVPWIHK 711
>gi|23957702 transmembrane protease, serine 6 [Homo sapiens]
Length = 811
Score = 194 bits (493), Expect = 2e-49
Identities = 125/371 (33%), Positives = 171/371 (46%), Gaps = 65/371 (17%)
Query: 156 ECDSSGTCINPSNWCDGVSHCPGGEDENRCVR-LYGPNFILQVYS-SQRKSWHPVCQDDW 213
+C TCI+ CDG C G DE +C + F Q S K +P C
Sbjct: 496 QCKEDSTCISLPKVCDGQPDCLNGSDEEQCQEGVPCGTFTFQCEDRSCVKKPNPQCD--- 552
Query: 214 NENYGRAACRDMGYKNNFYSSQGIVDDSGSTSFMKLNTSAGNVDIYKKLYHSDACSSKAV 273
GR CRD GS H D
Sbjct: 553 ----GRPDCRD-----------------GSDE-----------------EHCD------- 567
Query: 274 VSLRCIACGVNLNSSRQSRIVGGESALPGAWPWQVSLHVQNVHVCGGSIITPEWIVTAAH 333
CG+ SSR IVGG + G WPWQ SL V+ H+CGG++I W++TAAH
Sbjct: 568 -------CGLQGPSSR---IVGGAVSSEGEWPWQASLQVRGRHICGGALIADRWVITAAH 617
Query: 334 CV-EKPLNNPWHWTAFAGILRQSFMFYG-AGYQVEKVISHPNYDSKTKNNDIALMKLQKP 391
C E + + WT F G + Q+ + G ++V +++ HP ++ + + D+AL++L P
Sbjct: 618 CFQEDSMASTVLWTVFLGKVWQNSRWPGEVSFKVSRLLLHPYHEEDSHDYDVALLQLDHP 677
Query: 392 LTFNDLVKPVCLPNPGMMLQPEQLCWISGWGATEEKGKTSEVLNAAKVLLIETQRCNSRY 451
+ + V+PVCLP +P CWI+GWGA E G S L V LI C+ Y
Sbjct: 678 VVRSAAVRPVCLPARSHFFEPGLHCWITGWGALREGGPISNALQKVDVQLIPQDLCSEVY 737
Query: 452 VYDNLITPAMICAGFLQGNVDSCQGDSGGPLV-TSKNNIWWLIGDTSWGSGCAKAYRPGV 510
Y +TP M+CAG+ +G D+CQGDSGGPLV + + W+L G SWG GC + GV
Sbjct: 738 RYQ--VTPRMLCAGYRKGKKDACQGDSGGPLVCKALSGRWFLAGLVSWGLGCGRPNYFGV 795
Query: 511 YGNVMVFTDWI 521
Y + WI
Sbjct: 796 YTRITGVISWI 806
Score = 33.5 bits (75), Expect = 0.49
Identities = 14/30 (46%), Positives = 16/30 (53%), Gaps = 3/30 (10%)
Query: 157 CDSSGTCINPSNWCDGVSHCPGGEDENRCV 186
C +G C+ CDGV CP G DE CV
Sbjct: 464 CSVNGLCVPA---CDGVKDCPNGLDERNCV 490
Score = 31.2 bits (69), Expect = 2.5
Identities = 15/47 (31%), Positives = 19/47 (40%), Gaps = 1/47 (2%)
Query: 147 GSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRC-VRLYGPN 192
G C +C+ P+ CDG C G DE C L GP+
Sbjct: 528 GVPCGTFTFQCEDRSCVKKPNPQCDGRPDCRDGSDEEHCDCGLQGPS 574
>gi|40254871 transmembrane protease, serine 11E [Homo sapiens]
Length = 423
Score = 191 bits (486), Expect = 1e-48
Identities = 99/245 (40%), Positives = 138/245 (56%), Gaps = 9/245 (3%)
Query: 281 CGVNLNSS--RQSRIVGGESALPGAWPWQVSLHVQNVHVCGGSIITPEWIVTAAHCVEKP 338
CG + + + RIVGG G WPWQ SL H CG ++I W+V+AAHC
Sbjct: 178 CGTRRSKTLGQSLRIVGGTEVEEGEWPWQASLQWDGSHRCGATLINATWLVSAAHCFTT- 236
Query: 339 LNNPWHWTAFAGI-LRQSFMFYGAGYQVEKVISHPNYDSKTKNNDIALMKLQKPLTFNDL 397
NP WTA G+ ++ S M G + ++I H Y + + DI+L +L P+ + +
Sbjct: 237 YKNPARWTASFGVTIKPSKMKRG----LRRIIVHEKYKHPSHDYDISLAELSSPVPYTNA 292
Query: 398 VKPVCLPNPGMMLQPEQLCWISGWGATEEKGKTSEVLNAAKVLLIETQRCNSRYVYDNLI 457
V VCLP+ QP + +++G+GA + G + L A+V LI+ CN Y++ I
Sbjct: 293 VHRVCLPDASYEFQPGDVMFVTGFGALKNDGYSQNHLRQAQVTLIDATTCNEPQAYNDAI 352
Query: 458 TPAMICAGFLQGNVDSCQGDSGGPLVTS-KNNIWWLIGDTSWGSGCAKAYRPGVYGNVMV 516
TP M+CAG L+G D+CQGDSGGPLV+S +IW+L G SWG CAK +PGVY V
Sbjct: 353 TPRMLCAGSLEGKTDACQGDSGGPLVSSDARDIWYLAGIVSWGDECAKPNKPGVYTRVTA 412
Query: 517 FTDWI 521
DWI
Sbjct: 413 LRDWI 417
>gi|153791781 transmembrane protease, serine 11E2 [Homo sapiens]
Length = 423
Score = 191 bits (486), Expect = 1e-48
Identities = 99/245 (40%), Positives = 138/245 (56%), Gaps = 9/245 (3%)
Query: 281 CGVNLNSS--RQSRIVGGESALPGAWPWQVSLHVQNVHVCGGSIITPEWIVTAAHCVEKP 338
CG + + + RIVGG G WPWQ SL H CG ++I W+V+AAHC
Sbjct: 178 CGTRRSKTLGQSLRIVGGTEVEEGEWPWQASLQWDGSHRCGATLINATWLVSAAHCFTT- 236
Query: 339 LNNPWHWTAFAGI-LRQSFMFYGAGYQVEKVISHPNYDSKTKNNDIALMKLQKPLTFNDL 397
NP WTA G+ ++ S M G + ++I H Y + + DI+L +L P+ + +
Sbjct: 237 YKNPARWTASFGVTIKPSKMKRG----LRRIIVHEKYKHPSHDYDISLAELSSPVPYTNA 292
Query: 398 VKPVCLPNPGMMLQPEQLCWISGWGATEEKGKTSEVLNAAKVLLIETQRCNSRYVYDNLI 457
V VCLP+ QP + +++G+GA + G + L A+V LI+ CN Y++ I
Sbjct: 293 VHRVCLPDASYEFQPGDVMFVTGFGALKNDGYSQNHLRQAQVTLIDATTCNEPQAYNDAI 352
Query: 458 TPAMICAGFLQGNVDSCQGDSGGPLVTS-KNNIWWLIGDTSWGSGCAKAYRPGVYGNVMV 516
TP M+CAG L+G D+CQGDSGGPLV+S +IW+L G SWG CAK +PGVY V
Sbjct: 353 TPRMLCAGSLEGKTDACQGDSGGPLVSSDARDIWYLAGIVSWGDECAKPNKPGVYTRVTA 412
Query: 517 FTDWI 521
DWI
Sbjct: 413 LRDWI 417
>gi|187761337 transmembrane protease, serine 11B [Homo sapiens]
Length = 416
Score = 191 bits (484), Expect = 2e-48
Identities = 91/233 (39%), Positives = 135/233 (57%), Gaps = 7/233 (3%)
Query: 291 SRIVGGESALPGAWPWQVSLHVQNVHVCGGSIITPEWIVTAAHCVEKPLNNPWHWTAFAG 350
++IV G+S+L GAWPWQ S+ + H CG S+I+ W+++AAHC K NN WT G
Sbjct: 183 NKIVNGKSSLEGAWPWQASMQWKGRHYCGASLISSRWLLSAAHCFAKK-NNSKDWTVNFG 241
Query: 351 IL-RQSFMFYGAGYQVEKVISHPNYDSKTKNNDIALMKLQKPLTFNDLVKPVCLPNPGMM 409
I+ + +M +V+ +I H NY S ++DIAL++L + ++F + ++ +CLP M
Sbjct: 242 IVVNKPYMTR----KVQNIIFHENYSSPGLHDDIALVQLAEEVSFTEYIRKICLPEAKMK 297
Query: 410 LQPEQLCWISGWGATEEKGKTSEVLNAAKVLLIETQRCNSRYVYDNLITPAMICAGFLQG 469
L ++GWG G +L + +I+ + CN+ Y Y +T M+CAGF+ G
Sbjct: 298 LSENDNVVVTGWGTLYMNGSFPVILQEDFLKIIDNKICNASYAYSGFVTDTMLCAGFMSG 357
Query: 470 NVDSCQGDSGGPLV-TSKNNIWWLIGDTSWGSGCAKAYRPGVYGNVMVFTDWI 521
D+CQ DSGGPL NIW L+G SWG GC K +PGVY V + +WI
Sbjct: 358 EADACQNDSGGPLAYPDSRNIWHLVGIVSWGDGCGKKNKPGVYTRVTSYRNWI 410
>gi|148613878 acrosin precursor [Homo sapiens]
Length = 421
Score = 190 bits (482), Expect = 3e-48
Identities = 103/261 (39%), Positives = 146/261 (55%), Gaps = 24/261 (9%)
Query: 281 CGVNLNSSRQS--RIVGGESALPGAWPWQVSLHV-----QNVHVCGGSIITPEWIVTAAH 333
CG+ + Q RIVGG++A GAWPW VSL + H CGGS++ W++TAAH
Sbjct: 29 CGLRFRQNPQGGVRIVGGKAAQHGAWPWMVSLQIFTYNSHRYHTCGGSLLNSRWVLTAAH 88
Query: 334 CVEKPLNNPWHWTAFAGILRQSFMFYGAGYQV---------EKVISHPNYDSKTKNNDIA 384
C NN W G + YG V EK+I H Y+S T+ NDIA
Sbjct: 89 CFVGK-NNVHDWRLVFGAKE---ITYGNNKPVKAPLQERYVEKIIIHEKYNSATEGNDIA 144
Query: 385 LMKLQKPLTFNDLVKPVCLPN-PGMMLQPEQLCWISGWGATEEKG-KTSEVLNAAKVLLI 442
L+++ P++ + P CLP+ + + Q CW++GWG EEK + S +L A+V LI
Sbjct: 145 LVEITPPISCGRFIGPGCLPHFKAGLPRGSQSCWVAGWGYIEEKAPRPSSILMEARVDLI 204
Query: 443 ETQRCNSRYVYDNLITPAMICAGFLQGNVDSCQGDSGGPLV--TSKNNIWWLIGDTSWGS 500
+ CNS Y+ + P +CAG+ G +D+CQGDSGGPL+ SK + + ++G TSWG
Sbjct: 205 DLDLCNSTQWYNGRVQPTNVCAGYPVGKIDTCQGDSGGPLMCKDSKESAYVVVGITSWGV 264
Query: 501 GCAKAYRPGVYGNVMVFTDWI 521
GCA+A RPG+Y + +WI
Sbjct: 265 GCARAKRPGIYTATWPYLNWI 285
>gi|33667063 transmembrane protease, serine 9 [Homo sapiens]
Length = 1059
Score = 189 bits (481), Expect = 4e-48
Identities = 103/244 (42%), Positives = 138/244 (56%), Gaps = 6/244 (2%)
Query: 281 CGVNLNSSRQSRIVGGESALPGAWPWQVSLHVQNVHVCGGSIITPEWIVTAAHCVEKPLN 340
CG+ RIVGG A PG +PWQ SL H CG +II W+V+AAHC +
Sbjct: 191 CGLQPAWRMAGRIVGGMEASPGEFPWQASLRENKEHFCGAAIINARWLVSAAHCFNE-FQ 249
Query: 341 NPWHWTAFAGILRQSFMFYG-AGYQVEKVISHPNYDSKTKNNDIALMKLQKPLTFNDLVK 399
+P W A+ G S QV +++ HP Y++ T + D+A+++L PL F ++
Sbjct: 250 DPTKWVAYVGATYLSGSEASTVRAQVVQIVKHPLYNADTADFDVAVLELTSPLPFGRHIQ 309
Query: 400 PVCLPNPGMMLQPEQLCWISGWGATEEKGKTS-EVLNAAKVLLIETQRCNSRYVYDNLIT 458
PVCLP + P + C ISGWG +E EVL A V L++ C S +Y + +T
Sbjct: 310 PVCLPAATHIFPPSKKCLISGWGYLKEDFLVKPEVLQKATVELLDQALCAS--LYGHSLT 367
Query: 459 PAMICAGFLQGNVDSCQGDSGGPLVTSK-NNIWWLIGDTSWGSGCAKAYRPGVYGNVMVF 517
M+CAG+L G VDSCQGDSGGPLV + + ++L G SWG GCA+A RPGVY V
Sbjct: 368 DRMVCAGYLDGKVDSCQGDSGGPLVCEEPSGRFFLAGIVSWGIGCAEARRPGVYARVTRL 427
Query: 518 TDWI 521
DWI
Sbjct: 428 RDWI 431
Score = 174 bits (440), Expect = 2e-43
Identities = 101/246 (41%), Positives = 135/246 (54%), Gaps = 14/246 (5%)
Query: 281 CGVNLNSSRQSRIVGGESALPGAWPWQVSLHVQN-VHVCGGSIITPEWIVTAAHCVEKPL 339
CG L + +RIVGG +A G WPWQVSL ++ H CG ++ W+++AAHC +
Sbjct: 817 CG--LAPAALTRIVGGSAAGRGEWPWQVSLWLRRREHRCGAVLVAERWLLSAAHCFDV-Y 873
Query: 340 NNPWHWTAFAGILRQSFMFYGAGYQVEKVI---SHPNYDSKTKNNDIALMKLQKPLTFND 396
+P W AF G S GA Q+E+V HP Y+ T + D+AL++L P+ +
Sbjct: 874 GDPKQWAAFLGTPFLS----GAEGQLERVARIYKHPFYNLYTLDYDVALLELAGPVRRSR 929
Query: 397 LVKPVCLPNPGMMLQPEQLCWISGWGATEEKGKTSEVLNAAKVLLIETQRCNSRYVYDNL 456
LV+P+CLP P C I+GWG+ E G + L A V L+ Q C R Y
Sbjct: 930 LVRPICLPEPAPRPPDGTRCVITGWGSVREGGSMARQLQKAAVRLLSEQTC--RRFYPVQ 987
Query: 457 ITPAMICAGFLQGNVDSCQGDSGGPLVTSK-NNIWWLIGDTSWGSGCAKAYRPGVYGNVM 515
I+ M+CAGF QG VDSC GD+GGPL + + W L G TSWG GC + + PGVY V
Sbjct: 988 ISSRMLCAGFPQGGVDSCSGDAGGPLACREPSGRWVLTGVTSWGYGCGRPHFPGVYTRVA 1047
Query: 516 VFTDWI 521
WI
Sbjct: 1048 AVRGWI 1053
Score = 168 bits (426), Expect = 1e-41
Identities = 94/250 (37%), Positives = 136/250 (54%), Gaps = 11/250 (4%)
Query: 281 CGVNLNSSRQSRIVGGESALPGAWPWQVSLHVQNVHVCGGSIITPEWIVTAAHCVEKPLN 340
CG + +R+VGG A G PWQVSL + H CG +++ W+++AAHC N
Sbjct: 492 CGARPAMEKPTRVVGGFGAASGEVPWQVSLKEGSRHFCGATVVGDRWLLSAAHC----FN 547
Query: 341 NPWHWTAFAGILRQSFMFYGAG---YQVEKVISHPNYDSKTKNNDIALMKLQKPLTFNDL 397
+ A + S + G + +V+ HP Y+ + D+A+++L PL FN
Sbjct: 548 HTKVEQVRAHLGTASLLGLGGSPVKIGLRRVVLHPLYNPGILDFDLAVLELASPLAFNKY 607
Query: 398 VKPVCLPNPGMMLQPEQLCWISGWGATEEKGKTS-EVLNAAKVLLIETQRCNSRYVYDNL 456
++PVCLP + C ISGWG T+E T E+L A V +I+ + C+ +Y+
Sbjct: 608 IQPVCLPLAIQKFPVGRKCMISGWGNTQEGNATKPELLQKASVGIIDQKTCS--VLYNFS 665
Query: 457 ITPAMICAGFLQGNVDSCQGDSGGPLVTSK-NNIWWLIGDTSWGSGCAKAYRPGVYGNVM 515
+T MICAGFL+G VDSCQGDSGGPL + +++L G SWG GCA+ +PGVY +
Sbjct: 666 LTDRMICAGFLEGKVDSCQGDSGGPLACEEAPGVFYLAGIVSWGIGCAQVKKPGVYTRIT 725
Query: 516 VFTDWIYRQM 525
WI M
Sbjct: 726 RLKGWILEIM 735
>gi|110815798 ovochymase 1 [Homo sapiens]
Length = 1134
Score = 189 bits (479), Expect = 7e-48
Identities = 100/237 (42%), Positives = 141/237 (59%), Gaps = 10/237 (4%)
Query: 292 RIVGGESALPGAWPWQVSLHVQNVHVCGGSIITPEWIVTAAHCVEKPLNNPWHWTAFAGI 351
RI GGE A P WPWQV L + CGG+II P WI+TAAHCV+ NNP WT AG
Sbjct: 574 RIAGGEEACPHCWPWQVGLRFLGDYQCGGAIINPVWILTAAHCVQLK-NNPLSWTIIAGD 632
Query: 352 LRQSFMFYGAGYQVEK---VISHPNYDSKTKNNDIALMKLQKPLTFNDLVKPVCLPNPGM 408
++ + QV + +I H ++++ + ++DIAL++L PL +N +V+PVCLP+
Sbjct: 633 HDRNLK--ESTEQVRRAKHIIVHEDFNTLSYDSDIALIQLSSPLEYNSVVRPVCLPHSAE 690
Query: 409 MLQPEQLCWISGWGATEEKGKTSEVLNAAKVLLIETQRCNSRY--VYDNLITPAMICAGF 466
L ++C ++GWG+ G + L +V ++E + C Y + IT MICAGF
Sbjct: 691 PLFSSEICAVTGWGSISADGGLASRLQQIQVHVLEREVCEHTYYSAHPGGITEKMICAGF 750
Query: 467 -LQGNVDSCQGDSGGPLV-TSKNNIWWLIGDTSWGSGCAKAYRPGVYGNVMVFTDWI 521
G D CQGDSGGPLV +N + L G SWG+GC + ++PGV+ VM+F DWI
Sbjct: 751 AASGEKDFCQGDSGGPLVCRHENGPFVLYGIVSWGAGCVQPWKPGVFARVMIFLDWI 807
Score = 142 bits (358), Expect = 8e-34
Identities = 93/277 (33%), Positives = 140/277 (50%), Gaps = 27/277 (9%)
Query: 274 VSLRCIACGVNLNSSRQ-------SRIVGGESALPGAWPWQVSLHVQNVHVCGGSIITPE 326
+ L+C VN+ S SRI ++ PWQVSL H CGGS+I +
Sbjct: 21 LGLKCGIRMVNMKSKEPAVGSRFFSRISSWRNSTVTGHPWQVSLKSDEHHFCGGSLIQED 80
Query: 327 WIVTAAHCV----EKPLNNPWHWTAFAGILRQSFMFYGAGYQVEKVISHPNYDSKT-KNN 381
+VTAAHC+ EK L N + + ++ V K+I+HP Y+S+ +
Sbjct: 81 RVVTAAHCLDSLSEKQLKNITVTSGEYSLFQKDKQ--EQNIPVSKIITHPEYNSREYMSP 138
Query: 382 DIALMKLQKPLTFNDLVKPVCLPNPGMMLQPEQLCWISGWGATEEKGKTSEVLNAAKVLL 441
DIAL+ L+ + F + V+P+CLP+ ++P LC SGWG + + S VL ++ +
Sbjct: 139 DIALLYLKHKVKFGNAVQPICLPDSDDKVEPGILCLSSGWGKISKTSEYSNVLQEMELPI 198
Query: 442 IETQRCNSRYVYDNL--ITPAMICAGFLQGNVDSCQGDSGGPLVTSK-NNIWWLIGDTSW 498
++ + CN+ NL + M+CAGF +D+CQGDSGGPLV + IW L G TSW
Sbjct: 199 MDDRACNTVLKSMNLPPLGRTMLCAGFPDWGMDACQGDSGGPLVCRRGGGIWILAGITSW 258
Query: 499 GSGCAKAYRP----------GVYGNVMVFTDWIYRQM 525
+GCA P G++ V D+I + +
Sbjct: 259 VAGCAGGSVPVRNNHVKASLGIFSKVSELMDFITQNL 295
>gi|14602457 transmembrane protease, serine 3 isoform 3 [Homo
sapiens]
Length = 344
Score = 186 bits (471), Expect = 6e-47
Identities = 119/285 (41%), Positives = 153/285 (53%), Gaps = 20/285 (7%)
Query: 126 LTLGTFLVGAALAAGLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRC 185
+ +G + ALA GL F CS C SS CI CDGVS C GEDE RC
Sbjct: 52 IVIGIIALILALAIGLGIHF---DCSGK-YRCRSSFKCIELIARCDGVSDCKDGEDEYRC 107
Query: 186 VRLYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKNNFYSSQGIVDDSGSTS 245
VR+ G N +LQV+++ SW +C DDW +Y AC +G+ + + SS + S
Sbjct: 108 VRVGGQNAVLQVFTAA--SWKTMCSDDWKGHYANVACAQLGFPS-YVSSDNLRVSSLEGQ 164
Query: 246 FMKLNTSAGNV---DIYKKLYHS----DACSSKAVVSLRCIACGVNLNSSRQSRIVGGES 298
F + S ++ D L+HS + C+S VV+L+C ACG S SRIVGG
Sbjct: 165 FREEFVSIDHLLPDDKVTALHHSVYVREGCASGHVVTLQCTACGHRRGYS--SRIVGGNM 222
Query: 299 ALPGAWPWQVSLHVQNVHVCGGSIITPEWIVTAAHCVEKPLNNPWHWTAFAGILRQSFMF 358
+L WPWQ SL Q H+CGGS+ITP WI+TAAHCV L P WT G++ S +
Sbjct: 223 SLLSQWPWQASLQFQGYHLCGGSVITPLWIITAAHCV-YDLYLPKSWTIQVGLV--SLLD 279
Query: 359 YGA-GYQVEKVISHPNYDSKTKNNDIALMKLQKPLTFNDLVKPVC 402
A + VEK++ H Y K NDIALMKL PLTFN +C
Sbjct: 280 NPAPSHLVEKIVYHSKYKPKRLGNDIALMKLAGPLTFNGTSGSLC 324
>gi|167466252 transmembrane protease, serine 11A isoform 2 [Homo
sapiens]
Length = 418
Score = 183 bits (465), Expect = 3e-46
Identities = 94/244 (38%), Positives = 133/244 (54%), Gaps = 7/244 (2%)
Query: 280 ACGVNLNSSRQSRIVGGESALPGAWPWQVSLHVQNVHVCGGSIITPEWIVTAAHCVEKPL 339
+CG + +RI G A AWPWQ SL N+H CG ++I+ W+VTAAHC +K
Sbjct: 174 SCGKRVVPLNVNRIASGVIAPKAAWPWQASLQYDNIHQCGATLISNTWLVTAAHCFQK-Y 232
Query: 340 NNPWHWT-AFAGILRQSFMFYGAGYQVEKVISHPNYDSKTKNNDIALMKLQKPLTFNDLV 398
NP WT +F + M V + I H Y S + DIA++++ +TF+D +
Sbjct: 233 KNPHQWTVSFGTKINPPLM----KRNVRRFIIHEKYRSAAREYDIAVVQVSSRVTFSDDI 288
Query: 399 KPVCLPNPGMMLQPEQLCWISGWGATEEKGKTSEVLNAAKVLLIETQRCNSRYVYDNLIT 458
+ +CLP QP I+G+GA G++ L A+V +I C VY N I
Sbjct: 289 RQICLPEASASFQPNLTVHITGFGALYYGGESQNDLREARVKIISDDVCKQPQVYGNDIK 348
Query: 459 PAMICAGFLQGNVDSCQGDSGGPLVT-SKNNIWWLIGDTSWGSGCAKAYRPGVYGNVMVF 517
P M CAG+++G D+C+GDSGGPLVT + W+LIG SWG C + +PGVY V +
Sbjct: 349 PGMFCAGYMEGIYDACRGDSGGPLVTRDLKDTWYLIGIVSWGDNCGQKDKPGVYTQVTYY 408
Query: 518 TDWI 521
+WI
Sbjct: 409 RNWI 412
>gi|167466250 transmembrane protease, serine 11A isoform 1 [Homo
sapiens]
Length = 421
Score = 183 bits (465), Expect = 3e-46
Identities = 94/244 (38%), Positives = 133/244 (54%), Gaps = 7/244 (2%)
Query: 280 ACGVNLNSSRQSRIVGGESALPGAWPWQVSLHVQNVHVCGGSIITPEWIVTAAHCVEKPL 339
+CG + +RI G A AWPWQ SL N+H CG ++I+ W+VTAAHC +K
Sbjct: 177 SCGKRVVPLNVNRIASGVIAPKAAWPWQASLQYDNIHQCGATLISNTWLVTAAHCFQK-Y 235
Query: 340 NNPWHWT-AFAGILRQSFMFYGAGYQVEKVISHPNYDSKTKNNDIALMKLQKPLTFNDLV 398
NP WT +F + M V + I H Y S + DIA++++ +TF+D +
Sbjct: 236 KNPHQWTVSFGTKINPPLM----KRNVRRFIIHEKYRSAAREYDIAVVQVSSRVTFSDDI 291
Query: 399 KPVCLPNPGMMLQPEQLCWISGWGATEEKGKTSEVLNAAKVLLIETQRCNSRYVYDNLIT 458
+ +CLP QP I+G+GA G++ L A+V +I C VY N I
Sbjct: 292 RQICLPEASASFQPNLTVHITGFGALYYGGESQNDLREARVKIISDDVCKQPQVYGNDIK 351
Query: 459 PAMICAGFLQGNVDSCQGDSGGPLVT-SKNNIWWLIGDTSWGSGCAKAYRPGVYGNVMVF 517
P M CAG+++G D+C+GDSGGPLVT + W+LIG SWG C + +PGVY V +
Sbjct: 352 PGMFCAGYMEGIYDACRGDSGGPLVTRDLKDTWYLIGIVSWGDNCGQKDKPGVYTQVTYY 411
Query: 518 TDWI 521
+WI
Sbjct: 412 RNWI 415
>gi|21614531 testisin isoform 2 [Homo sapiens]
Length = 312
Score = 181 bits (460), Expect = 1e-45
Identities = 97/249 (38%), Positives = 131/249 (52%), Gaps = 11/249 (4%)
Query: 291 SRIVGGESALPGAWPWQVSLHVQNVHVCGGSIITPEWIVTAAHCVEKPLNNPWHWTAFAG 350
SRIVGGE A G WPWQ SL + + HVCG S+++ W +TAAHC E L++P W G
Sbjct: 40 SRIVGGEDAELGRWPWQGSLRLWDSHVCGVSLLSHRWALTAAHCFETDLSDPSGWMVQFG 99
Query: 351 ILRQ-----SFMFYGAGYQVEKVISHPNYDSKTKNNDIALMKLQKPLTFNDLVKPVCLPN 405
L S Y Y V + P Y + DIAL+KL P+T+ ++P+CL
Sbjct: 100 QLTSMPSFWSLQAYYTRYFVSNIYLSPRYLGNSPY-DIALVKLSAPVTYTKHIQPICLQA 158
Query: 406 PGMMLQPEQLCWISGWGATEEKGK--TSEVLNAAKVLLIETQRCNS---RYVYDNLITPA 460
+ CW++GWG +E + L +V +I CN +Y + I
Sbjct: 159 STFEFENRTDCWVTGWGYIKEDEALPSPHTLQEVQVAIINNSMCNHLFLKYSFRKDIFGD 218
Query: 461 MICAGFLQGNVDSCQGDSGGPLVTSKNNIWWLIGDTSWGSGCAKAYRPGVYGNVMVFTDW 520
M+CAG QG D+C GDSGGPL +KN +W+ IG SWG GC + RPGVY N+ +W
Sbjct: 219 MVCAGNAQGGKDACFGDSGGPLACNKNGLWYQIGVVSWGVGCGRPNRPGVYTNISHHFEW 278
Query: 521 IYRQMRADG 529
I + M G
Sbjct: 279 IQKLMAQSG 287
>gi|13994276 marapsin [Homo sapiens]
Length = 290
Score = 180 bits (456), Expect = 3e-45
Identities = 89/242 (36%), Positives = 129/242 (53%), Gaps = 9/242 (3%)
Query: 291 SRIVGGESALPGAWPWQVSLHVQNVHVCGGSIITPEWIVTAAHCVEKPLNNPWHWTAFAG 350
+R+VGG+ G WPWQVS+ H CGGS+I +W++TAAHC +
Sbjct: 33 NRMVGGQDTQEGEWPWQVSIQRNGSHFCGGSLIAEQWVLTAAHCFRNTSETSLYQVLLGA 92
Query: 351 ILRQSFMFYGAGYQVEKVISHPNYDSKTKNNDIALMKLQKPLTFNDLVKPVCLPNPGMML 410
+ +V +V S+P Y + D+AL++L+ P+ F + + PVCLP+P ++
Sbjct: 93 RQLVQPGPHAMYARVRQVESNPLYQGTASSADVALVELEAPVPFTNYILPVCLPDPSVIF 152
Query: 411 QPEQLCWISGWGATEEKGKTSE--VLNAAKVLLIETQRCNSRYVYDN-------LITPAM 461
+ CW++GWG+ E+ E +L V +I+T +CN Y D I M
Sbjct: 153 ETGMNCWVTGWGSPSEEDLLPEPRILQKLAVPIIDTPKCNLLYSKDTEFGYQPKTIKNDM 212
Query: 462 ICAGFLQGNVDSCQGDSGGPLVTSKNNIWWLIGDTSWGSGCAKAYRPGVYGNVMVFTDWI 521
+CAGF +G D+C+GDSGGPLV W G SWG GCA+ RPGVY V +WI
Sbjct: 213 LCAGFEEGKKDACKGDSGGPLVCLVGQSWLQAGVISWGEGCARQNRPGVYIRVTAHHNWI 272
Query: 522 YR 523
+R
Sbjct: 273 HR 274
>gi|117956391 protease, serine, 33 [Homo sapiens]
Length = 280
Score = 180 bits (456), Expect = 3e-45
Identities = 95/252 (37%), Positives = 136/252 (53%), Gaps = 14/252 (5%)
Query: 280 ACGVNLNSSRQSRIVGGESALPGAWPWQVSLHVQNVHVCGGSIITPEWIVTAAHCVEKPL 339
ACG SRIVGG G WPWQ S+ + HVCGGS+I P+W++TAAHC +
Sbjct: 27 ACG---QPRMSSRIVGGRDGRDGEWPWQASIQHRGAHVCGGSLIAPQWVLTAAHCFPRRA 83
Query: 340 NNPWHWTAFAGILRQ-SFMFYGAGYQVEKVISHPNYDSKTKNNDIALMKLQKPLTFNDLV 398
P + G LR S V +V+ P+Y D+AL++L++P+ + V
Sbjct: 84 L-PAEYRVRLGALRLGSTSPRTLSVPVRRVLLPPDYSEDGARGDLALLQLRRPVPLSARV 142
Query: 399 KPVCLPNPGMMLQPEQLCWISGWGATEEKGKTSE--VLNAAKVLLIETQRCNSRYVY--- 453
+PVCLP PG P C ++GWG+ E L +V L++++ C+ Y
Sbjct: 143 QPVCLPVPGARPPPGTPCRVTGWGSLRPGVPLPEWRPLQGVRVPLLDSRTCDGLYHVGAD 202
Query: 454 ----DNLITPAMICAGFLQGNVDSCQGDSGGPLVTSKNNIWWLIGDTSWGSGCAKAYRPG 509
+ ++ P +CAG+ QG+ D+CQGDSGGPL ++ W L+G SWG GCA RPG
Sbjct: 203 VPQAERIVLPGSLCAGYPQGHKDACQGDSGGPLTCLQSGSWVLVGVVSWGKGCALPNRPG 262
Query: 510 VYGNVMVFTDWI 521
VY +V ++ WI
Sbjct: 263 VYTSVATYSPWI 274
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.134 0.438
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,171,079
Number of Sequences: 37866
Number of extensions: 1220740
Number of successful extensions: 4813
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 211
Number of HSP's successfully gapped in prelim test: 62
Number of HSP's that attempted gapping in prelim test: 3758
Number of HSP's gapped (non-prelim): 611
length of query: 529
length of database: 18,247,518
effective HSP length: 107
effective length of query: 422
effective length of database: 14,195,856
effective search space: 5990651232
effective search space used: 5990651232
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.