Guide to the Human Genome
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Search of human proteins with 22748811

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|22748811 hypothetical protein LOC127795 [Homo sapiens]
         (546 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|22748811 hypothetical protein LOC127795 [Homo sapiens]            1095   0.0  
gi|153792074 proline rich 12 [Homo sapiens]                            38   0.021
gi|5802980 activating transcription factor 7 isoform 2 [Homo sap...    37   0.036
gi|21450775 torsin A interacting protein 2 [Homo sapiens]              37   0.046
gi|38569480 megakaryoblastic leukemia 2 protein [Homo sapiens]         35   0.14 
gi|156104897 inositol polyphosphate-4-phosphatase, type II, 105k...    35   0.23 
gi|156104895 inositol polyphosphate-4-phosphatase, type II, 105k...    35   0.23 
gi|148727319 thioredoxin domain-containing 2 isoform 2 [Homo sap...    34   0.30 
gi|7657138 golgi integral membrane protein 4 [Homo sapiens]            34   0.30 
gi|38570109 CAP-binding protein complex interacting protein 1 is...    34   0.39 
gi|38570107 CAP-binding protein complex interacting protein 1 is...    34   0.39 
gi|117190342 PHD finger protein 2 [Homo sapiens]                       34   0.39 
gi|15721939 metastatic lymph node 51 [Homo sapiens]                    34   0.39 
gi|110349719 titin isoform N2-A [Homo sapiens]                         33   0.51 
gi|67514036 SH3-domain kinase binding protein 1 isoform b [Homo ...    33   0.67 
gi|13994242 SH3-domain kinase binding protein 1 isoform a [Homo ...    33   0.67 
gi|31652242 transcription factor 20 isoform 2 [Homo sapiens]           33   0.88 
gi|31652244 transcription factor 20 isoform 1 [Homo sapiens]           33   0.88 
gi|8923842 forkhead box J2 [Homo sapiens]                              33   0.88 
gi|55741709 RNA binding motif protein 25 [Homo sapiens]                32   1.1  
gi|109255234 centrosomal protein 290kDa [Homo sapiens]                 32   1.1  
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ...    32   1.1  
gi|197927454 DEK oncogene isoform 2 [Homo sapiens]                     32   1.1  
gi|4503249 DEK oncogene isoform 1 [Homo sapiens]                       32   1.1  
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa...    32   1.1  
gi|119226220 membrane-spanning 4-domains, subfamily A, member 14...    32   1.1  
gi|119226217 membrane-spanning 4-domains, subfamily A, member 14...    32   1.1  
gi|110349717 titin isoform novex-2 [Homo sapiens]                      32   1.5  
gi|110349713 titin isoform novex-1 [Homo sapiens]                      32   1.5  
gi|110349715 titin isoform N2-B [Homo sapiens]                         32   1.5  

>gi|22748811 hypothetical protein LOC127795 [Homo sapiens]
          Length = 546

 Score = 1095 bits (2832), Expect = 0.0
 Identities = 546/546 (100%), Positives = 546/546 (100%)

Query: 1   MSSAWKTPRGSDAMPEIMVKIIGSKHFQYLVEKPKIKENDSLKTETQTMHQKPMTDNARQ 60
           MSSAWKTPRGSDAMPEIMVKIIGSKHFQYLVEKPKIKENDSLKTETQTMHQKPMTDNARQ
Sbjct: 1   MSSAWKTPRGSDAMPEIMVKIIGSKHFQYLVEKPKIKENDSLKTETQTMHQKPMTDNARQ 60

Query: 61  MSRDTPVPINFTDQQTTDNPDDVKEKKHPENNQKSENNQKLLTGANSSRFLDGNIPSQAN 120
           MSRDTPVPINFTDQQTTDNPDDVKEKKHPENNQKSENNQKLLTGANSSRFLDGNIPSQAN
Sbjct: 61  MSRDTPVPINFTDQQTTDNPDDVKEKKHPENNQKSENNQKLLTGANSSRFLDGNIPSQAN 120

Query: 121 VHCSSVPTGDQSLSYVHGIPRRKLRDWSLEQMVRGSSDQPEDIGQSPSGTTNEDAFLLAL 180
           VHCSSVPTGDQSLSYVHGIPRRKLRDWSLEQMVRGSSDQPEDIGQSPSGTTNEDAFLLAL
Sbjct: 121 VHCSSVPTGDQSLSYVHGIPRRKLRDWSLEQMVRGSSDQPEDIGQSPSGTTNEDAFLLAL 180

Query: 181 VRRELKSRPLSSNLLEKLQKELKILDPISSGFLLQSQLSRLFLKHEVPLQLPTVKILCQR 240
           VRRELKSRPLSSNLLEKLQKELKILDPISSGFLLQSQLSRLFLKHEVPLQLPTVKILCQR
Sbjct: 181 VRRELKSRPLSSNLLEKLQKELKILDPISSGFLLQSQLSRLFLKHEVPLQLPTVKILCQR 240

Query: 241 FSKRGSPEMVNYEKLLWFLNSAASDYPQQNKAAADLRKTESHGTHSQSTPPQHSSSQPEV 300
           FSKRGSPEMVNYEKLLWFLNSAASDYPQQNKAAADLRKTESHGTHSQSTPPQHSSSQPEV
Sbjct: 241 FSKRGSPEMVNYEKLLWFLNSAASDYPQQNKAAADLRKTESHGTHSQSTPPQHSSSQPEV 300

Query: 301 NRSLLEILKMALRTTNGRLNIDNLNLSFRKEDRSFSGCLPLPKVRAICGKHGLYLTLSLL 360
           NRSLLEILKMALRTTNGRLNIDNLNLSFRKEDRSFSGCLPLPKVRAICGKHGLYLTLSLL
Sbjct: 301 NRSLLEILKMALRTTNGRLNIDNLNLSFRKEDRSFSGCLPLPKVRAICGKHGLYLTLSLL 360

Query: 361 ETLLNHQDLGYQNEIKWQNFVEMLTRASSDLLSDLPTGKNEKKAPAPPMEPEVPEMSQSK 420
           ETLLNHQDLGYQNEIKWQNFVEMLTRASSDLLSDLPTGKNEKKAPAPPMEPEVPEMSQSK
Sbjct: 361 ETLLNHQDLGYQNEIKWQNFVEMLTRASSDLLSDLPTGKNEKKAPAPPMEPEVPEMSQSK 420

Query: 421 TEHMKTPEEELQPESSPAETSACKDPLKPLKIRPVSQPFVNPAVKNKAEECETWIDRFRK 480
           TEHMKTPEEELQPESSPAETSACKDPLKPLKIRPVSQPFVNPAVKNKAEECETWIDRFRK
Sbjct: 421 TEHMKTPEEELQPESSPAETSACKDPLKPLKIRPVSQPFVNPAVKNKAEECETWIDRFRK 480

Query: 481 LENALYLCDLSNTGVLEKERARRLIHNYNLIYNLSLSPQKIDQALRRFRSGENMLLEPAL 540
           LENALYLCDLSNTGVLEKERARRLIHNYNLIYNLSLSPQKIDQALRRFRSGENMLLEPAL
Sbjct: 481 LENALYLCDLSNTGVLEKERARRLIHNYNLIYNLSLSPQKIDQALRRFRSGENMLLEPAL 540

Query: 541 RYLKEL 546
           RYLKEL
Sbjct: 541 RYLKEL 546


>gi|153792074 proline rich 12 [Homo sapiens]
          Length = 2036

 Score = 38.1 bits (87), Expect = 0.021
 Identities = 25/55 (45%), Positives = 31/55 (56%), Gaps = 9/55 (16%)

Query: 403  KAPAPPMEPEVPEMSQSKTEHMKTPEEELQPESSPAETSACKDPLKPLKIRPVSQ 457
            KAPAPP +PE PE    KT   K PE+   PE++  E  A   P KP  +RPV +
Sbjct: 1695 KAPAPPPKPETPE----KTTSEKPPEQ--TPETAMPEPPA---PEKPSLLRPVEK 1740


>gi|5802980 activating transcription factor 7 isoform 2 [Homo
           sapiens]
          Length = 483

 Score = 37.4 bits (85), Expect = 0.036
 Identities = 26/92 (28%), Positives = 44/92 (47%), Gaps = 11/92 (11%)

Query: 363 LLNHQDLGYQNEIKWQNFVEMLTRASSDLLSDLPTGKNEKKAPAPPMEPEVPEMSQSKTE 422
           L N +++G  NE+   +F     +A+ +         +EKKA A P++  +P     K +
Sbjct: 58  LKNCEEVGLFNELA-SSFEHEFKKAADE---------DEKKAAAGPLDMSLPSTPDIKIK 107

Query: 423 HMKTPEEELQPESSPAETSACKDPLKPLKIRP 454
             +  E +  P  SPA +S C  PLK  ++ P
Sbjct: 108 EEEPVEVDSSPPDSPA-SSPCSPPLKEKEVTP 138


>gi|21450775 torsin A interacting protein 2 [Homo sapiens]
          Length = 470

 Score = 37.0 bits (84), Expect = 0.046
 Identities = 30/145 (20%), Positives = 56/145 (38%), Gaps = 8/145 (5%)

Query: 64  DTPVPINFTDQQTTDNPDDVKEKKHPENNQKSENNQKLLTGANSSRFLDGNI------PS 117
           +T  P +      +++PD+    KHP++  + EN Q  L G         N+      P 
Sbjct: 57  ETEGPESADTGDKSESPDEANVGKHPKDKTEDENKQSFLDGGKGHHLPSENLGKEPLDPD 116

Query: 118 QANVHCSSVPTGDQSLSYVHGIPRRKLRD--WSLEQMVRGSSDQPEDIGQSPSGTTNEDA 175
            ++     V   D  L        ++  D   + ++     S + +  G S +G   ED 
Sbjct: 117 PSHSPSDKVGRADAHLGSSSVALPKEASDGTGASQEPPTTDSQEAQSPGHSSAGQEGEDT 176

Query: 176 FLLALVRRELKSRPLSSNLLEKLQK 200
               L+  E  S P  +  LE++++
Sbjct: 177 LRRRLLAPEAGSHPQQTQKLEEIKE 201


>gi|38569480 megakaryoblastic leukemia 2 protein [Homo sapiens]
          Length = 1049

 Score = 35.4 bits (80), Expect = 0.14
 Identities = 34/120 (28%), Positives = 52/120 (43%), Gaps = 21/120 (17%)

Query: 388 SSDLLS-DLPTGKNEKKAPAPPMEPEVPE---------------MSQSKTEHMKTPEEEL 431
           SSD LS D P  +  + + A P EP+V E               +S +  E +KTP    
Sbjct: 191 SSDALSPDQPASQESQGSAASPSEPKVSESPSPVTTNTPAQFASVSPTVPEFLKTPPTAD 250

Query: 432 QPESSPAETSACKDPLKPLKIRPV----SQPFVNPAVKNKAEECETWIDRFRKLENALYL 487
           QP   PA      + +   K  P     S P  NP  K+++++C+    R +KL+   Y+
Sbjct: 251 QPPPRPAAPVLPTNTVSSAKPGPALVKQSHP-KNPNDKHRSKKCKDPKPRVKKLKYHQYI 309


>gi|156104897 inositol polyphosphate-4-phosphatase, type II, 105kD
           [Homo sapiens]
          Length = 924

 Score = 34.7 bits (78), Expect = 0.23
 Identities = 31/123 (25%), Positives = 52/123 (42%), Gaps = 21/123 (17%)

Query: 229 LQLPTVKILCQRFSKRGSPEMVNYEKLLWFLNSAA--SDYPQQNKAAADLR----KTESH 282
           +Q+  +  + Q  ++  S E+V   +   FL      S+YP   +    L     K +SH
Sbjct: 63  VQISVIHPVEQSLTRYSSTEIVEGTRDPLFLTGVTFPSEYPIYEETKIKLTVYDVKDKSH 122

Query: 283 GTHSQSTPPQHSSSQPEVNRSLL---------------EILKMALRTTNGRLNIDNLNLS 327
            T   S  P+H    PEV RS L               ++L ++LRT++G   +  + +S
Sbjct: 123 DTVRTSVLPEHKDPPPEVGRSFLGYASFKVGELLKSKEQLLVLSLRTSDGGKVVGTIEVS 182

Query: 328 FRK 330
             K
Sbjct: 183 VVK 185


>gi|156104895 inositol polyphosphate-4-phosphatase, type II, 105kD
           [Homo sapiens]
          Length = 924

 Score = 34.7 bits (78), Expect = 0.23
 Identities = 31/123 (25%), Positives = 52/123 (42%), Gaps = 21/123 (17%)

Query: 229 LQLPTVKILCQRFSKRGSPEMVNYEKLLWFLNSAA--SDYPQQNKAAADLR----KTESH 282
           +Q+  +  + Q  ++  S E+V   +   FL      S+YP   +    L     K +SH
Sbjct: 63  VQISVIHPVEQSLTRYSSTEIVEGTRDPLFLTGVTFPSEYPIYEETKIKLTVYDVKDKSH 122

Query: 283 GTHSQSTPPQHSSSQPEVNRSLL---------------EILKMALRTTNGRLNIDNLNLS 327
            T   S  P+H    PEV RS L               ++L ++LRT++G   +  + +S
Sbjct: 123 DTVRTSVLPEHKDPPPEVGRSFLGYASFKVGELLKSKEQLLVLSLRTSDGGKVVGTIEVS 182

Query: 328 FRK 330
             K
Sbjct: 183 VVK 185


>gi|148727319 thioredoxin domain-containing 2 isoform 2 [Homo
           sapiens]
          Length = 553

 Score = 34.3 bits (77), Expect = 0.30
 Identities = 65/292 (22%), Positives = 123/292 (42%), Gaps = 26/292 (8%)

Query: 181 VRRELKSRPLSSNLLEKLQKELKILDPISSGFLLQSQLSRLFLKHEVPLQLPTVKILCQR 240
           V +EL    + +    K +  L   +  S G   +S L  L L   VPL       + Q 
Sbjct: 3   VDKELGMESVKAGASGKPEMRLGTQEETSEGDANESSL--LVLSSNVPLLALEFLEIAQA 60

Query: 241 FSKRGSPEMVNYEKLLWFLNSAASDYPQQNKAAADLRKTESHGTH-SQSTPPQHSSSQPE 299
             K   P MV++    + + +  SD  Q+     DL K+ ++ +H  Q   P+  SS+  
Sbjct: 61  KEKAFLP-MVSHT---FHMRTEESDASQEGD---DLPKSSANTSHPKQDDSPK--SSEET 111

Query: 300 VNRSLLEILKMALRTTNGRLNIDNLNLSFRKEDRSFSGCLPLPKVRAICGKHGLYLTLSL 359
           +     +I K    T   +   ++L  S  K  +     +P    + I  K G     S+
Sbjct: 112 IQPKEGDIPKAPEETIQSKK--EDLPKSSEKAIQPKESNIPKSSAKPIQPKLGNIPKASV 169

Query: 360 LETLLNHQDLGYQNEIKWQNFVEMLTRASSDLLSDLPTGKNEKKAPAPPMEPEVPEMSQS 419
             +     D+    E   Q+  E L ++S + +   P   +  K+ A P++P++  ++++
Sbjct: 170 KPSQPKEGDIPKAPEETIQSKKEDLPKSSEEAIQ--PKEGDIPKSSAKPIQPKLGNIAKT 227

Query: 420 --------KTEHMKTPEEELQPESSPAETSACKDPLKPLKIRPVSQPFVNPA 463
                   +++  K+PEE +QP+      S+ K P++P K+  + +  V P+
Sbjct: 228 SVKPSQPKESDIPKSPEETIQPKEGDIPKSSAK-PIQP-KLGNIPKASVKPS 277


>gi|7657138 golgi integral membrane protein 4 [Homo sapiens]
          Length = 696

 Score = 34.3 bits (77), Expect = 0.30
 Identities = 28/78 (35%), Positives = 38/78 (48%), Gaps = 7/78 (8%)

Query: 367 QDLGYQNEIKWQNFVEMLTRASSDLLSDLPTGKN-EKKAPAPPMEPEV----PEMSQSKT 421
           Q++   N++ WQN   +  RA    L   PT K  E +AP  P++ EV    PE  Q + 
Sbjct: 280 QEVSRNNDV-WQNHEAVPGRAEDTKLY-APTHKEAEFQAPPEPIQQEVERREPEEHQVEE 337

Query: 422 EHMKTPEEELQPESSPAE 439
           EH K  EEE   +   AE
Sbjct: 338 EHRKALEEEEMEQVGQAE 355


>gi|38570109 CAP-binding protein complex interacting protein 1 isoform
            b [Homo sapiens]
          Length = 1349

 Score = 33.9 bits (76), Expect = 0.39
 Identities = 34/161 (21%), Positives = 64/161 (39%), Gaps = 13/161 (8%)

Query: 276  LRKTESHGTHSQSTPPQHSSSQPEVNRSLLEILKMALRTTNGRLNIDNLNLSFRKEDRSF 335
            L +T           P  +S +   +R +L  L  A+ +     +   +   F   D   
Sbjct: 986  LEETADEWAEKMPKGPPPTSPKATADRDILARLHKAVTS-----HYHAITQEFENFDTMK 1040

Query: 336  SGCLPLPKVRAICGKHGLYLTLSLLETLLNHQDLGYQNEIKWQNFVEMLTRASSD-LLSD 394
            +  +   + RAIC +    LT    + L N   +  +  +K+ +F   L+R SS+   + 
Sbjct: 1041 TNTISREEFRAICNRRVQILTDEQFDRLWNEMPVNAKGRLKYPDF---LSRFSSETAATP 1097

Query: 395  LPTGKNEKKAPAPPMEPEVPEMSQSKTEHMKTPEEELQPES 435
            + TG     +        VP++S+     +  P +EL+P S
Sbjct: 1098 MATG----DSAVAQRGSSVPDVSEGTRSALSLPTQELRPGS 1134



 Score = 29.3 bits (64), Expect = 9.7
 Identities = 39/202 (19%), Positives = 73/202 (36%), Gaps = 14/202 (6%)

Query: 191 SSNLLEKLQKELKILDPISSGFLLQSQLSRLFLKHEVPLQLPTVKILCQRFSKRGSPEMV 250
           + N    L K     D   +G L +  +       ++PL     + L  R+   G   + 
Sbjct: 693 AKNRWSDLSKNFLETDNEGNGILRRRDIKNALYGFDIPLTPREFEKLWARYDTEGKGHIT 752

Query: 251 NYEKLLWFLNSAASDYPQ--QNKAAADLRKTESHGTHSQSTPPQHSSSQPEVNRSLLEIL 308
             E    FL     +Y        A D      H T  Q    +    Q    +++    
Sbjct: 753 YQE----FLQKLGINYSPAVHRPCAEDYFNFMGHFTKPQQLQEEMKELQQSTEKAVAARD 808

Query: 309 KMALRTTNGRLNIDNLNLSFRKEDRSFSGCLPLPKVRAICGKHGLYLTLSLLETLLNHQD 368
           K+  R         +++ +F K D+S +  + + K++ +  + G  LT   L  LLN   
Sbjct: 809 KLMDRH-------QDISKAFTKTDQSKTNYISICKMQEVLEECGCSLTEGELTHLLNSWG 861

Query: 369 LG-YQNEIKWQNFVEMLTRASS 389
           +  + N I + +F+  +  + S
Sbjct: 862 VSRHDNAINYLDFLRAVENSKS 883


>gi|38570107 CAP-binding protein complex interacting protein 1 isoform
            a [Homo sapiens]
          Length = 1501

 Score = 33.9 bits (76), Expect = 0.39
 Identities = 34/161 (21%), Positives = 64/161 (39%), Gaps = 13/161 (8%)

Query: 276  LRKTESHGTHSQSTPPQHSSSQPEVNRSLLEILKMALRTTNGRLNIDNLNLSFRKEDRSF 335
            L +T           P  +S +   +R +L  L  A+ +     +   +   F   D   
Sbjct: 1138 LEETADEWAEKMPKGPPPTSPKATADRDILARLHKAVTS-----HYHAITQEFENFDTMK 1192

Query: 336  SGCLPLPKVRAICGKHGLYLTLSLLETLLNHQDLGYQNEIKWQNFVEMLTRASSD-LLSD 394
            +  +   + RAIC +    LT    + L N   +  +  +K+ +F   L+R SS+   + 
Sbjct: 1193 TNTISREEFRAICNRRVQILTDEQFDRLWNEMPVNAKGRLKYPDF---LSRFSSETAATP 1249

Query: 395  LPTGKNEKKAPAPPMEPEVPEMSQSKTEHMKTPEEELQPES 435
            + TG     +        VP++S+     +  P +EL+P S
Sbjct: 1250 MATG----DSAVAQRGSSVPDVSEGTRSALSLPTQELRPGS 1286



 Score = 29.3 bits (64), Expect = 9.7
 Identities = 39/202 (19%), Positives = 73/202 (36%), Gaps = 14/202 (6%)

Query: 191  SSNLLEKLQKELKILDPISSGFLLQSQLSRLFLKHEVPLQLPTVKILCQRFSKRGSPEMV 250
            + N    L K     D   +G L +  +       ++PL     + L  R+   G   + 
Sbjct: 845  AKNRWSDLSKNFLETDNEGNGILRRRDIKNALYGFDIPLTPREFEKLWARYDTEGKGHIT 904

Query: 251  NYEKLLWFLNSAASDYPQ--QNKAAADLRKTESHGTHSQSTPPQHSSSQPEVNRSLLEIL 308
              E    FL     +Y        A D      H T  Q    +    Q    +++    
Sbjct: 905  YQE----FLQKLGINYSPAVHRPCAEDYFNFMGHFTKPQQLQEEMKELQQSTEKAVAARD 960

Query: 309  KMALRTTNGRLNIDNLNLSFRKEDRSFSGCLPLPKVRAICGKHGLYLTLSLLETLLNHQD 368
            K+  R         +++ +F K D+S +  + + K++ +  + G  LT   L  LLN   
Sbjct: 961  KLMDRH-------QDISKAFTKTDQSKTNYISICKMQEVLEECGCSLTEGELTHLLNSWG 1013

Query: 369  LG-YQNEIKWQNFVEMLTRASS 389
            +  + N I + +F+  +  + S
Sbjct: 1014 VSRHDNAINYLDFLRAVENSKS 1035


>gi|117190342 PHD finger protein 2 [Homo sapiens]
          Length = 1096

 Score = 33.9 bits (76), Expect = 0.39
 Identities = 25/76 (32%), Positives = 35/76 (46%), Gaps = 7/76 (9%)

Query: 382 EMLTRASSDLLSDLPTGKNEKKAPAPPMEPEVPEMSQSKTEHMKTPEEELQPESS----P 437
           E+ T ASSD + D   G  EK+ P  P+E   P+    K    KTP+    P+ S    P
Sbjct: 452 EVNTVASSDEVCD---GDREKEEPPSPIEATPPQSLLEKVSKKKTPKTVKMPKPSKIPKP 508

Query: 438 AETSACKDPLKPLKIR 453
            +      P K LK++
Sbjct: 509 PKPPKPPRPPKTLKLK 524


>gi|15721939 metastatic lymph node 51 [Homo sapiens]
          Length = 703

 Score = 33.9 bits (76), Expect = 0.39
 Identities = 25/106 (23%), Positives = 48/106 (45%), Gaps = 6/106 (5%)

Query: 33  KPKIKENDSLKTETQTMHQKPMTDNARQMSRDTPVPINFTDQQTTDNPDDVKEK-----K 87
           +PK ++    K E +  H K   D     SR   + +   D ++  NPDD+K +     +
Sbjct: 203 RPKGRQRKLWKDEGRWEHDKFREDEQAPKSRQELIALYGYDIRSAHNPDDIKPRRIRKPR 262

Query: 88  HPENNQKSEN-NQKLLTGANSSRFLDGNIPSQANVHCSSVPTGDQS 132
           +    Q+  N N + L  ++  + L G +P +  ++ ++  TG  S
Sbjct: 263 YGSPPQRDPNWNGERLNKSHRHQGLGGTLPPRTFINRNAAGTGRMS 308


>gi|110349719 titin isoform N2-A [Homo sapiens]
          Length = 33423

 Score = 33.5 bits (75), Expect = 0.51
 Identities = 21/65 (32%), Positives = 29/65 (44%), Gaps = 7/65 (10%)

Query: 401   EKKAPAPP-MEPEVPEMSQSKTEHMKTPEEEL------QPESSPAETSACKDPLKPLKIR 453
             EKK P PP  +PEVP     +      PE+++      +PES P E       + P K  
Sbjct: 10535 EKKVPVPPPKKPEVPPTKVPEVPKAAVPEKKVPEAIPPKPESPPPEVPEAPKEVVPEKKV 10594

Query: 454   PVSQP 458
             P + P
Sbjct: 10595 PAAPP 10599



 Score = 32.0 bits (71), Expect = 1.5
 Identities = 24/77 (31%), Positives = 34/77 (44%), Gaps = 9/77 (11%)

Query: 394   DLPT-GKNEKKAPAPPMEPEVPEMSQSKTEHMKTPEEELQPESSPAETSACKDPLKPLKI 452
             ++PT  K E+K P P   PE+          +  PE + +PE   AE    K P    + 
Sbjct: 10990 EVPTVTKRERKIPEPTKVPEIKPAIP-----LPAPEPKPKPE---AEVKTIKPPPVEPEP 11041

Query: 453   RPVSQPFVNPAVKNKAE 469
              P++ P   P V  KAE
Sbjct: 11042 TPIAAPVTVPVVGKKAE 11058



 Score = 30.0 bits (66), Expect = 5.7
 Identities = 17/46 (36%), Positives = 24/46 (52%), Gaps = 7/46 (15%)

Query: 401   EKKAPAPP-MEPEVPEMSQSKTEHMKTPEEEL------QPESSPAE 439
             EKK P PP  +PEVP     +   +  PE+++      +PES P E
Sbjct: 10619 EKKVPVPPPKKPEVPPTKVPEVPKVAVPEKKVPEAIPPKPESPPPE 10664



 Score = 29.6 bits (65), Expect = 7.4
 Identities = 24/76 (31%), Positives = 35/76 (46%), Gaps = 5/76 (6%)

Query: 395  LPTGKNEKKAPAPPMEPEVPEMSQSKTEHMKTPEEELQPESSPAETSACKDPLKPLKIRP 454
            +P    EKKAP PP   + P + + +    +  EE++Q    P E S    P KP +  P
Sbjct: 9165 VPAKVPEKKAPPPPKVIKKPVIEKIEKTSRRMEEEKVQVTKVP-EVSKKIVPQKPSR-TP 9222

Query: 455  VSQPFVN---PAVKNK 467
            V +  +    PAV  K
Sbjct: 9223 VQEEVIEVKVPAVHTK 9238


>gi|67514036 SH3-domain kinase binding protein 1 isoform b [Homo
           sapiens]
          Length = 628

 Score = 33.1 bits (74), Expect = 0.67
 Identities = 33/110 (30%), Positives = 49/110 (44%), Gaps = 9/110 (8%)

Query: 398 GKNEKKAPAPPMEPEVPEMSQSKTEHMKTPEEE----LQPESSPAETSACKDPLKPLKIR 453
           G  E+K     + PE PEM  ++TE  + PE E    LQ  S PA     K P +P K  
Sbjct: 316 GTTERKHEIKKIPPERPEMLPNRTEEKERPEREPKLDLQKPSVPAIPP--KKP-RPPKTN 372

Query: 454 PVSQPFVNPAVKNKAEECETWIDRFRKLENALYLCDLSNTGVLEKERARR 503
            +S+P   P    + E     +   R     + L   S +G+L+K+ + R
Sbjct: 373 SLSRPGALP--PRRPERPVGPLTHTRGDSPKIDLAGSSLSGILDKDLSDR 420


>gi|13994242 SH3-domain kinase binding protein 1 isoform a [Homo
           sapiens]
          Length = 665

 Score = 33.1 bits (74), Expect = 0.67
 Identities = 33/110 (30%), Positives = 49/110 (44%), Gaps = 9/110 (8%)

Query: 398 GKNEKKAPAPPMEPEVPEMSQSKTEHMKTPEEE----LQPESSPAETSACKDPLKPLKIR 453
           G  E+K     + PE PEM  ++TE  + PE E    LQ  S PA     K P +P K  
Sbjct: 353 GTTERKHEIKKIPPERPEMLPNRTEEKERPEREPKLDLQKPSVPAIPP--KKP-RPPKTN 409

Query: 454 PVSQPFVNPAVKNKAEECETWIDRFRKLENALYLCDLSNTGVLEKERARR 503
            +S+P   P    + E     +   R     + L   S +G+L+K+ + R
Sbjct: 410 SLSRPGALP--PRRPERPVGPLTHTRGDSPKIDLAGSSLSGILDKDLSDR 457


>gi|31652242 transcription factor 20 isoform 2 [Homo sapiens]
          Length = 1938

 Score = 32.7 bits (73), Expect = 0.88
 Identities = 20/79 (25%), Positives = 38/79 (48%), Gaps = 9/79 (11%)

Query: 399  KNEKKAPAPPMEPEVPEMS---QSKTEHMKTPEEELQPESSPAETSACK-----DPLKP- 449
            K ++  P PP  P++PE S   + K +  +   E  +P + P +    +     +P +P 
Sbjct: 1552 KQQQPPPPPPQPPQIPEGSADGEPKPKKQRQRRERRKPGAQPRKRKTKQAVPIVEPQEPE 1611

Query: 450  LKIRPVSQPFVNPAVKNKA 468
            +K++  +QP      KNK+
Sbjct: 1612 IKLKYATQPLDKTDAKNKS 1630


>gi|31652244 transcription factor 20 isoform 1 [Homo sapiens]
          Length = 1960

 Score = 32.7 bits (73), Expect = 0.88
 Identities = 20/79 (25%), Positives = 38/79 (48%), Gaps = 9/79 (11%)

Query: 399  KNEKKAPAPPMEPEVPEMS---QSKTEHMKTPEEELQPESSPAETSACK-----DPLKP- 449
            K ++  P PP  P++PE S   + K +  +   E  +P + P +    +     +P +P 
Sbjct: 1552 KQQQPPPPPPQPPQIPEGSADGEPKPKKQRQRRERRKPGAQPRKRKTKQAVPIVEPQEPE 1611

Query: 450  LKIRPVSQPFVNPAVKNKA 468
            +K++  +QP      KNK+
Sbjct: 1612 IKLKYATQPLDKTDAKNKS 1630


>gi|8923842 forkhead box J2 [Homo sapiens]
          Length = 574

 Score = 32.7 bits (73), Expect = 0.88
 Identities = 18/83 (21%), Positives = 37/83 (44%), Gaps = 8/83 (9%)

Query: 364 LNHQDLGYQNEIKWQNFVEMLTRAS----SDLLSDLPTGKN----EKKAPAPPMEPEVPE 415
           +N QDL +     +++ +E  + +S    S LL D+P   N    +++ P PP + +  +
Sbjct: 246 INFQDLSWSFRNLYKSMLEKSSSSSQHGFSSLLGDIPPSNNYYMYQQQQPPPPQQQQQQQ 305

Query: 416 MSQSKTEHMKTPEEELQPESSPA 438
                      P+++  P   P+
Sbjct: 306 QPPQPPPQQSQPQQQQAPAQGPS 328


>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
          Length = 843

 Score = 32.3 bits (72), Expect = 1.1
 Identities = 15/53 (28%), Positives = 24/53 (45%)

Query: 402 KKAPAPPMEPEVPEMSQSKTEHMKTPEEELQPESSPAETSACKDPLKPLKIRP 454
           ++ P    EPE  E  + K E  +  EE ++ E  P +    K  L+P+   P
Sbjct: 572 RRQPQIKQEPESEEEEEEKQEKEEKREEPMEEEEEPEQKPCLKPTLRPISSAP 624


>gi|109255234 centrosomal protein 290kDa [Homo sapiens]
          Length = 2479

 Score = 32.3 bits (72), Expect = 1.1
 Identities = 22/72 (30%), Positives = 34/72 (47%), Gaps = 5/72 (6%)

Query: 30   LVEKPKI-KENDSLKTE----TQTMHQKPMTDNARQMSRDTPVPINFTDQQTTDNPDDVK 84
            L EK +I +END LK +    T  +  KP+TDN + +  +    +   + Q     ++V 
Sbjct: 1837 LREKEEIDQENDELKRQIKRLTSGLQGKPLTDNKQSLIEELQRKVKKLENQLEGKVEEVD 1896

Query: 85   EKKHPENNQKSE 96
             K   E N K E
Sbjct: 1897 LKPMKEKNAKEE 1908


>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
           sapiens]
          Length = 5537

 Score = 32.3 bits (72), Expect = 1.1
 Identities = 21/61 (34%), Positives = 31/61 (50%), Gaps = 5/61 (8%)

Query: 402 KKAPAPPMEPEVPEMSQSKTEHMKTPEEELQPESSPAETSACKDPLKPLKIRPVSQPFVN 461
           ++ PA P+ PE   +S+   E   +P  E  P S P E+S    P  PL+  P+S P  +
Sbjct: 472 EELPASPL-PEALHLSRPLEESPLSPPPEESPLSPPPESS----PFSPLEESPLSPPEES 526

Query: 462 P 462
           P
Sbjct: 527 P 527



 Score = 30.4 bits (67), Expect = 4.3
 Identities = 25/81 (30%), Positives = 34/81 (41%), Gaps = 6/81 (7%)

Query: 386  RASSDLLSDLPTGKNEKKAPAPPMEPEVP-EMSQSKTEHMKTPE-EELQPESSPAETSAC 443
            ++  D+LS L   K E  AP PP +      +S      +  P  EE  P  SP   S  
Sbjct: 4870 KSQLDILSLL---KQESPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSPA 4926

Query: 444  KDPLKPLKIRPVSQPFVNPAV 464
              P +PL   P ++P   P V
Sbjct: 4927 SPPTEPLVELP-TEPLAEPPV 4946



 Score = 29.3 bits (64), Expect = 9.7
 Identities = 22/79 (27%), Positives = 30/79 (37%), Gaps = 8/79 (10%)

Query: 392 LSDLPTGKNEKKAPAPPME------PEVPEMSQSKTEHMKTPEEELQPESSPAETSACKD 445
           L + P    E+  P+P +E      PE   +S    E   +P  E  P S P E S    
Sbjct: 515 LEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSP 574

Query: 446 PLK--PLKIRPVSQPFVNP 462
           P +  P+   P   P   P
Sbjct: 575 PPEESPMSPPPEESPMSPP 593


>gi|197927454 DEK oncogene isoform 2 [Homo sapiens]
          Length = 341

 Score = 32.3 bits (72), Expect = 1.1
 Identities = 19/75 (25%), Positives = 35/75 (46%)

Query: 32  EKPKIKENDSLKTETQTMHQKPMTDNARQMSRDTPVPINFTDQQTTDNPDDVKEKKHPEN 91
           EKPK K     K   ++ + K    +  + ++++    + ++  + D P   K KK P +
Sbjct: 229 EKPKQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKESESEDSSDDEPLIKKLKKPPTD 288

Query: 92  NQKSENNQKLLTGAN 106
            +  E  +KLL  AN
Sbjct: 289 EELKETIKKLLASAN 303


>gi|4503249 DEK oncogene isoform 1 [Homo sapiens]
          Length = 375

 Score = 32.3 bits (72), Expect = 1.1
 Identities = 19/75 (25%), Positives = 35/75 (46%)

Query: 32  EKPKIKENDSLKTETQTMHQKPMTDNARQMSRDTPVPINFTDQQTTDNPDDVKEKKHPEN 91
           EKPK K     K   ++ + K    +  + ++++    + ++  + D P   K KK P +
Sbjct: 263 EKPKQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKESESEDSSDDEPLIKKLKKPPTD 322

Query: 92  NQKSENNQKLLTGAN 106
            +  E  +KLL  AN
Sbjct: 323 EELKETIKKLLASAN 337


>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
           sapiens]
          Length = 2715

 Score = 32.3 bits (72), Expect = 1.1
 Identities = 20/71 (28%), Positives = 27/71 (38%), Gaps = 11/71 (15%)

Query: 399 KNEKKAPAPPMEPEVPEMSQSKTEHMKTPEEELQPESSPAETSACKDPLKPLKIRPVSQP 458
           K E K P PP+ P  P           +P   L P S+      C  P  P+   P+  P
Sbjct: 396 KEEAKLPPPPLTPPAP-----------SPPPPLPPPSTSPPPPLCPPPPPPVSPPPLPSP 444

Query: 459 FVNPAVKNKAE 469
              PA + + E
Sbjct: 445 PPPPAQEEQEE 455


>gi|119226220 membrane-spanning 4-domains, subfamily A, member 14
           isoform 2 [Homo sapiens]
          Length = 662

 Score = 32.3 bits (72), Expect = 1.1
 Identities = 29/139 (20%), Positives = 55/139 (39%), Gaps = 17/139 (12%)

Query: 183 RELKSRPLSSNLLEKLQKELKILDPISSGFLLQSQLSRLFLKHEVPLQLPTVKILCQRFS 242
           +++K   L S +++  Q + K+L   ++   +    S L L+   P  LP+  +  +  S
Sbjct: 255 KQMKDEDLQSAIVQPSQMQTKLLQDQAASLQVFPSHSALKLEDISPEDLPSQALPVEGLS 314

Query: 243 KRGSPEMVNYEKLLWFLNSAASDYPQQNKAAADLRKTE-----------------SHGTH 285
           ++  P       +    N  A+D P Q   + D    +                 S  T 
Sbjct: 315 EQTMPSKSTSSHVKQSSNLTANDLPPQGILSQDTSSQDMLFHDMTSQDMQSLDMLSQDTP 374

Query: 286 SQSTPPQHSSSQPEVNRSL 304
           S + PPQ   SQ  ++++L
Sbjct: 375 SHAMPPQDIPSQDMLSQAL 393


>gi|119226217 membrane-spanning 4-domains, subfamily A, member 14
           isoform 1 [Homo sapiens]
          Length = 679

 Score = 32.3 bits (72), Expect = 1.1
 Identities = 29/139 (20%), Positives = 55/139 (39%), Gaps = 17/139 (12%)

Query: 183 RELKSRPLSSNLLEKLQKELKILDPISSGFLLQSQLSRLFLKHEVPLQLPTVKILCQRFS 242
           +++K   L S +++  Q + K+L   ++   +    S L L+   P  LP+  +  +  S
Sbjct: 272 KQMKDEDLQSAIVQPSQMQTKLLQDQAASLQVFPSHSALKLEDISPEDLPSQALPVEGLS 331

Query: 243 KRGSPEMVNYEKLLWFLNSAASDYPQQNKAAADLRKTE-----------------SHGTH 285
           ++  P       +    N  A+D P Q   + D    +                 S  T 
Sbjct: 332 EQTMPSKSTSSHVKQSSNLTANDLPPQGILSQDTSSQDMLFHDMTSQDMQSLDMLSQDTP 391

Query: 286 SQSTPPQHSSSQPEVNRSL 304
           S + PPQ   SQ  ++++L
Sbjct: 392 SHAMPPQDIPSQDMLSQAL 410


>gi|110349717 titin isoform novex-2 [Homo sapiens]
          Length = 27118

 Score = 32.0 bits (71), Expect = 1.5
 Identities = 24/77 (31%), Positives = 34/77 (44%), Gaps = 9/77 (11%)

Query: 394  DLPT-GKNEKKAPAPPMEPEVPEMSQSKTEHMKTPEEELQPESSPAETSACKDPLKPLKI 452
            ++PT  K E+K P P   PE+          +  PE + +PE   AE    K P    + 
Sbjct: 4685 EVPTVTKRERKIPEPTKVPEIKPAIP-----LPAPEPKPKPE---AEVKTIKPPPVEPEP 4736

Query: 453  RPVSQPFVNPAVKNKAE 469
             P++ P   P V  KAE
Sbjct: 4737 TPIAAPVTVPVVGKKAE 4753


>gi|110349713 titin isoform novex-1 [Homo sapiens]
          Length = 27051

 Score = 32.0 bits (71), Expect = 1.5
 Identities = 24/77 (31%), Positives = 34/77 (44%), Gaps = 9/77 (11%)

Query: 394  DLPT-GKNEKKAPAPPMEPEVPEMSQSKTEHMKTPEEELQPESSPAETSACKDPLKPLKI 452
            ++PT  K E+K P P   PE+          +  PE + +PE   AE    K P    + 
Sbjct: 4618 EVPTVTKRERKIPEPTKVPEIKPAIP-----LPAPEPKPKPE---AEVKTIKPPPVEPEP 4669

Query: 453  RPVSQPFVNPAVKNKAE 469
             P++ P   P V  KAE
Sbjct: 4670 TPIAAPVTVPVVGKKAE 4686


>gi|110349715 titin isoform N2-B [Homo sapiens]
          Length = 26926

 Score = 32.0 bits (71), Expect = 1.5
 Identities = 24/77 (31%), Positives = 34/77 (44%), Gaps = 9/77 (11%)

Query: 394  DLPT-GKNEKKAPAPPMEPEVPEMSQSKTEHMKTPEEELQPESSPAETSACKDPLKPLKI 452
            ++PT  K E+K P P   PE+          +  PE + +PE   AE    K P    + 
Sbjct: 4493 EVPTVTKRERKIPEPTKVPEIKPAIP-----LPAPEPKPKPE---AEVKTIKPPPVEPEP 4544

Query: 453  RPVSQPFVNPAVKNKAE 469
             P++ P   P V  KAE
Sbjct: 4545 TPIAAPVTVPVVGKKAE 4561


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.129    0.371 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,489,421
Number of Sequences: 37866
Number of extensions: 1086016
Number of successful extensions: 4461
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 20
Number of HSP's successfully gapped in prelim test: 77
Number of HSP's that attempted gapping in prelim test: 4319
Number of HSP's gapped (non-prelim): 249
length of query: 546
length of database: 18,247,518
effective HSP length: 107
effective length of query: 439
effective length of database: 14,195,856
effective search space: 6231980784
effective search space used: 6231980784
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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