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Search of human proteins with 226371735
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|226371735 iroquois homeobox 3 [Homo sapiens]
(501 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|226371735 iroquois homeobox 3 [Homo sapiens] 1013 0.0
gi|51479177 iroquois homeobox protein 1 [Homo sapiens] 326 3e-89
gi|139394646 iroquois homeobox protein 5 [Homo sapiens] 222 5e-58
gi|197100900 iroquois homeobox 2 [Homo sapiens] 219 3e-57
gi|39930475 iroquois homeobox 2 [Homo sapiens] 219 3e-57
gi|7705555 iroquois homeobox 4 [Homo sapiens] 216 3e-56
gi|42544241 iroquois homeobox protein 6 [Homo sapiens] 202 4e-52
gi|178057337 mohawk homeobox [Homo sapiens] 80 6e-15
gi|55741677 SET domain containing 1A [Homo sapiens] 67 3e-11
gi|55750053 atrophin-1 [Homo sapiens] 66 6e-11
gi|55750041 atrophin-1 [Homo sapiens] 66 6e-11
gi|24497556 homeobox A7 [Homo sapiens] 61 2e-09
gi|116812644 PBX/knotted 1 homeobox 2 [Homo sapiens] 60 6e-09
gi|24431933 reticulon 4 isoform B [Homo sapiens] 58 2e-08
gi|47519490 reticulon 4 isoform D [Homo sapiens] 58 2e-08
gi|24431935 reticulon 4 isoform A [Homo sapiens] 58 2e-08
gi|28178843 TG-interacting factor isoform a [Homo sapiens] 57 3e-08
gi|4507473 TG-interacting factor isoform c [Homo sapiens] 57 3e-08
gi|28178855 TG-interacting factor isoform d [Homo sapiens] 57 3e-08
gi|28178853 TG-interacting factor isoform d [Homo sapiens] 57 3e-08
gi|28178851 TG-interacting factor isoform d [Homo sapiens] 57 3e-08
gi|28178857 TG-interacting factor isoform d [Homo sapiens] 57 3e-08
gi|28178849 TG-interacting factor isoform c [Homo sapiens] 57 3e-08
gi|28178845 TG-interacting factor isoform b [Homo sapiens] 57 3e-08
gi|28866955 PBX/knotted 1 homeobox 1 [Homo sapiens] 57 5e-08
gi|12056969 homeobox C8 [Homo sapiens] 56 7e-08
gi|210032580 SET domain containing 1B [Homo sapiens] 56 7e-08
gi|149158690 HLA-B associated transcript-2 [Homo sapiens] 56 9e-08
gi|89257348 homeo box HB9 [Homo sapiens] 56 9e-08
gi|21735415 centromere protein B [Homo sapiens] 55 1e-07
>gi|226371735 iroquois homeobox 3 [Homo sapiens]
Length = 501
Score = 1013 bits (2618), Expect = 0.0
Identities = 501/501 (100%), Positives = 501/501 (100%)
Query: 1 MSFPQLGYQYIRPLYPSERPGAAGGSGGSAGARGGLGAGASELNASGSLSNVLSSVYGAP 60
MSFPQLGYQYIRPLYPSERPGAAGGSGGSAGARGGLGAGASELNASGSLSNVLSSVYGAP
Sbjct: 1 MSFPQLGYQYIRPLYPSERPGAAGGSGGSAGARGGLGAGASELNASGSLSNVLSSVYGAP 60
Query: 61 YAAAAAAAAAQGYGAFLPYAAELPIFPQLGAQYELKDSPGVQHPAAAAAFPHPHPAFYPY 120
YAAAAAAAAAQGYGAFLPYAAELPIFPQLGAQYELKDSPGVQHPAAAAAFPHPHPAFYPY
Sbjct: 61 YAAAAAAAAAQGYGAFLPYAAELPIFPQLGAQYELKDSPGVQHPAAAAAFPHPHPAFYPY 120
Query: 121 GQYQFGDPSRPKNATRESTSTLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFAN 180
GQYQFGDPSRPKNATRESTSTLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFAN
Sbjct: 121 GQYQFGDPSRPKNATRESTSTLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFAN 180
Query: 181 ARRRLKKENKMTWAPRSRTDEEGNAYGSEREEEDEEEDEEDGKRELELEEEELGGEEEDT 240
ARRRLKKENKMTWAPRSRTDEEGNAYGSEREEEDEEEDEEDGKRELELEEEELGGEEEDT
Sbjct: 181 ARRRLKKENKMTWAPRSRTDEEGNAYGSEREEEDEEEDEEDGKRELELEEEELGGEEEDT 240
Query: 241 GGEGLADDDEDEEIDLENLDGAATEPELSLAGAARRDGDLGLGPISDSKNSDSEDSSEGL 300
GGEGLADDDEDEEIDLENLDGAATEPELSLAGAARRDGDLGLGPISDSKNSDSEDSSEGL
Sbjct: 241 GGEGLADDDEDEEIDLENLDGAATEPELSLAGAARRDGDLGLGPISDSKNSDSEDSSEGL 300
Query: 301 EDRPLPVLSLAPAPPPVAVASPSLPSPPVSLDPCAPAPAPASALQKPKIWSLAETATSPD 360
EDRPLPVLSLAPAPPPVAVASPSLPSPPVSLDPCAPAPAPASALQKPKIWSLAETATSPD
Sbjct: 301 EDRPLPVLSLAPAPPPVAVASPSLPSPPVSLDPCAPAPAPASALQKPKIWSLAETATSPD 360
Query: 361 NPRRSPPGAGGSPPGAAVAPSALQLSPAAAAAAAHRLVSAPLGKFPAWTNRPFPGPPPGP 420
NPRRSPPGAGGSPPGAAVAPSALQLSPAAAAAAAHRLVSAPLGKFPAWTNRPFPGPPPGP
Sbjct: 361 NPRRSPPGAGGSPPGAAVAPSALQLSPAAAAAAAHRLVSAPLGKFPAWTNRPFPGPPPGP 420
Query: 421 RLHPLSLLGSAPPHLLGLPGAAGHPAAAAAFARPAEPEGGTDRCSALEVEKKLLKTAFQP 480
RLHPLSLLGSAPPHLLGLPGAAGHPAAAAAFARPAEPEGGTDRCSALEVEKKLLKTAFQP
Sbjct: 421 RLHPLSLLGSAPPHLLGLPGAAGHPAAAAAFARPAEPEGGTDRCSALEVEKKLLKTAFQP 480
Query: 481 VPRRPQNHLDAALVLSALSSS 501
VPRRPQNHLDAALVLSALSSS
Sbjct: 481 VPRRPQNHLDAALVLSALSSS 501
>gi|51479177 iroquois homeobox protein 1 [Homo sapiens]
Length = 480
Score = 326 bits (836), Expect = 3e-89
Identities = 223/508 (43%), Positives = 276/508 (54%), Gaps = 76/508 (14%)
Query: 1 MSFPQLGY-QYIRPL----YPSERPGAAGGSGGSAGARGGLGAGASELNASGSLSNVLSS 55
MSFPQLGY QY+ Y ERPG + +A A GA+EL G+ + ++S
Sbjct: 1 MSFPQLGYPQYLSAAGPGAYGGERPGVLAAAAAAAAAASSGRPGAAELGG-GAGAAAVTS 59
Query: 56 VYGAPYAAAAAAAAAQGYGAFLPYAAELPIFPQLGAQYELKDSPGVQHPAAAAAFPHPHP 115
V G YAAA A A Y AFLPYAA+L +F Q+G+QYELKD+PGV HPA AA H P
Sbjct: 60 VLGM-YAAAGPYAGAPNYSAFLPYAADLSLFSQMGSQYELKDNPGV-HPATFAA--HTAP 115
Query: 116 AFYPYGQYQFGDPSRPKNATRESTSTLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVS 175
A+YPYGQ+Q+GDP RPKNATRESTSTLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVS
Sbjct: 116 AYYPYGQFQYGDPGRPKNATRESTSTLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVS 175
Query: 176 TWFANARRRLKKENKMTWAPRSRTDEEGNAYGSEREEEDEEEDEEDGKRELELEEEELGG 235
TWFANARRRLKKENK+TW RS+ E+G +GS+ E + E+ ++++ E++LE ++
Sbjct: 176 TWFANARRRLKKENKVTWGARSKDQEDGALFGSDTEGDPEKAEDDE---EIDLESIDIDK 232
Query: 236 EEEDTGGEGLADDDEDEEIDLENLDGAATEPELSLAGAARRDGDLGLGPISDSKNSDSED 295
+E G + DD++ E A + + AR G P++ + +D
Sbjct: 233 IDEHDGDQSNEDDEDKAE---------APHAPAAPSALARDQG----SPLAAADVLKPQD 279
Query: 296 SSEGLEDRPLPVLSLAPAPPPVAVASPSLPSPPVSLDPCAPAPAPASALQ-----KPKIW 350
S PL + AP P + SP A A LQ KPKIW
Sbjct: 280 S-------PLGLAKEAPEPGSTRLLSPG---------------AAAGGLQGAPHGKPKIW 317
Query: 351 SLAETATSPDN-PRRSPPGAGGSPPGAAVAPSALQLSPAAAAAAAHRLVSAPLGKFPAWT 409
SLAETATSPD P+ SPP G P A PSA A +H L + +GKF WT
Sbjct: 318 SLAETATSPDGAPKASPPPPAGHP--GAHGPSAGAPLQHPAFLPSHGLYTCHIGKFSNWT 375
Query: 410 NRPFPGPPPGPRLHPLSLLGSAPPHL------LGLPGAAGHPAA----------AAAFAR 453
N F G L+ S LG PH L P P A A+ +
Sbjct: 376 NSAFLA--QGSLLNMRSFLGVGAPHAAPHGPHLPAPPPPQPPVAIAPGALNGDKASVRSS 433
Query: 454 PAEPEGGTDRCSALEVEKKLLKTAFQPV 481
P PE D + + LK+ FQPV
Sbjct: 434 PTLPE--RDLVPRPDSPAQQLKSPFQPV 459
>gi|139394646 iroquois homeobox protein 5 [Homo sapiens]
Length = 483
Score = 222 bits (566), Expect = 5e-58
Identities = 160/402 (39%), Positives = 200/402 (49%), Gaps = 48/402 (11%)
Query: 59 APYAAAAA-AAAAQGYGAFLPYAAELPIFPQLGAQYELKDSPGVQHPAAAAAFPHPHPAF 117
+PYA + A A + GY + L Y A+ P A SP P A + + HP
Sbjct: 46 SPYAGSTAFTAPSPGYNSHLQYGAD-PAAAAAAAFSSYVGSPYDHTPGMAGSLGY-HPYA 103
Query: 118 YPYGQYQFGDPSRPKNATRESTSTLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTW 177
P G Y +GDP+ KNATR++T+TLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTW
Sbjct: 104 APLGSYPYGDPAYRKNATRDATATLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTW 163
Query: 178 FANARRRLKKENKMTWAPRSRTDEEGNAYGSEREEEDEEEDEE-------DGKRELELEE 230
FANARRRLKKENKMTW PR+R+++E + E+ DE+E ++ +G E+
Sbjct: 164 FANARRRLKKENKMTWTPRNRSEDEEEEENIDLEKNDEDEPQKPEDKGDPEGPEAGGAEQ 223
Query: 231 EELGGEEEDTGGEGLADDDEDEEIDLENLDGAATEPEL-SLAGAARRDGDLGLGPISDSK 289
+ G E G A + + + + +E L +L G R G GP +
Sbjct: 224 KAASGCERLQGPPTPAGKETEGSLSDSDFKEPPSEGRLDALQGPPRTGGPSPAGPAAARL 283
Query: 290 NSDSEDSSEGLEDRPLPVLSLAPAPPPVAVASPSLPSPPVSLDPCAPAPAPASALQKPKI 349
D P + AP P P A P P P S+ P P P + L KPK+
Sbjct: 284 AEDPAPH--------YPAGAPAPGPHPAAGEVPPGPGGP-SVIHSPPPPPPPAVLAKPKL 334
Query: 350 WSLAETATSPDNPRRSPPGAGGSP----PGAAVAPSALQLSPAAAAAAAHRLVSA----P 401
WSLAE ATS D + G GSP PG +A AL S A+ A A R SA P
Sbjct: 335 WSLAEIATSSDKVKDGGGGNEGSPCPPCPG-PIAGQALGGSRASPAPAPSRSPSAQCPFP 393
Query: 402 LGK------------FPAWTN-------RPFPGPPPGPRLHP 424
G +P +TN PGP PGP P
Sbjct: 394 GGTVLSRPLYYTAPFYPGYTNYGSFGHLHGHPGPGPGPTTGP 435
>gi|197100900 iroquois homeobox 2 [Homo sapiens]
Length = 471
Score = 219 bits (559), Expect = 3e-57
Identities = 188/502 (37%), Positives = 236/502 (47%), Gaps = 72/502 (14%)
Query: 1 MSFPQLGYQYIRPLYPSERPGAAGGSGGSAGARGGLGAGASELNASGSLSNVLSSVYGAP 60
MS+PQ GY Y + PG+ A L A SE A + + S P
Sbjct: 1 MSYPQ-GYLY-------QAPGSLALYSCPAYGASALAAPRSEELARSASGSAFSPY---P 49
Query: 61 YAAAAAAAAAQGYGAFLPYAAELPI----FPQ-LGAQYELKDSPGV----QHPAAAAAFP 111
+AA A AA G+G+ L Y+A+ FP +GA Y+ + HP +AA+P
Sbjct: 50 GSAAFTAQAATGFGSPLQYSADAAAAAAGFPSYMGAPYDAHTTGMTGAISYHPYGSAAYP 109
Query: 112 HPHPAFYPYGQYQFGDPSRPKNATRESTSTLKAWLNEHRKNPYPTKGEKIMLAIITKMTL 171
YQ DP+ KNATR++T+TLKAWLNEHRKNPYPTKGEKIMLAIITKMTL
Sbjct: 110 -----------YQLNDPAYRKNATRDATATLKAWLNEHRKNPYPTKGEKIMLAIITKMTL 158
Query: 172 TQVSTWFANARRRLKKENKMTWAPRSRTDEEGNAYGSEREEEDEEEDEEDGKRELELEEE 231
TQVSTWFANARRRLKKENKMTWAPR+++++E G +DE D+ E E+E
Sbjct: 159 TQVSTWFANARRRLKKENKMTWAPRNKSEDEDEDEGDATRSKDESPDKAQEGTETSAEDE 218
Query: 232 ELGGEEEDTGGEGLADDDEDEEIDLENLDGAATEPELSLAGAARRD--GDLGLGPISDSK 289
+ + L D E D E L A +P L +G+ +D DL +
Sbjct: 219 GI-----SLHVDSLTDHSCSAESDGEKLPCRAGDP-LCESGSECKDKYDDL------EDD 266
Query: 290 NSDSEDSSEGLEDRPLPVLSL------AP--APPPVAVASPSLPSPPVS-LDPCAPAPAP 340
D E+ GL P PV S AP +PPP A +P S P AP PA
Sbjct: 267 EDDDEEGERGLAP-PKPVTSSPLTGLEAPLLSPPPEAAPRGGRKTPQGSRTSPGAPPPA- 324
Query: 341 ASALQKPKIWSLAETATSPDNPRRSPPGAGGSPPG--AAVAPSALQLSPAAAAAAAHRLV 398
KPK+WSLAE ATS PG G PPG AA AP++ P + A L+
Sbjct: 325 ----SKPKLWSLAEIATSDLKQPSLGPGCG--PPGLPAAAAPASTGAPPGGSPYPASPLL 378
Query: 399 SAPLGKFPAWTNRPFPGPPPGPRLHPLSLLGSAPPHLLGLPGAAGHPAAAAAFARPAEPE 458
PL + PF G +L G LL AA P A A A +
Sbjct: 379 GRPL-----YYTSPFYGNYTNYGNLNAALQGQG---LLRYNSAAAAPGEALHTAPKAASD 430
Query: 459 GGTDRCSALEVEKKLLKTAFQP 480
G LE + ++P
Sbjct: 431 AGKAGAHPLESHYRSPGGGYEP 452
>gi|39930475 iroquois homeobox 2 [Homo sapiens]
Length = 471
Score = 219 bits (559), Expect = 3e-57
Identities = 188/502 (37%), Positives = 236/502 (47%), Gaps = 72/502 (14%)
Query: 1 MSFPQLGYQYIRPLYPSERPGAAGGSGGSAGARGGLGAGASELNASGSLSNVLSSVYGAP 60
MS+PQ GY Y + PG+ A L A SE A + + S P
Sbjct: 1 MSYPQ-GYLY-------QAPGSLALYSCPAYGASALAAPRSEELARSASGSAFSPY---P 49
Query: 61 YAAAAAAAAAQGYGAFLPYAAELPI----FPQ-LGAQYELKDSPGV----QHPAAAAAFP 111
+AA A AA G+G+ L Y+A+ FP +GA Y+ + HP +AA+P
Sbjct: 50 GSAAFTAQAATGFGSPLQYSADAAAAAAGFPSYMGAPYDAHTTGMTGAISYHPYGSAAYP 109
Query: 112 HPHPAFYPYGQYQFGDPSRPKNATRESTSTLKAWLNEHRKNPYPTKGEKIMLAIITKMTL 171
YQ DP+ KNATR++T+TLKAWLNEHRKNPYPTKGEKIMLAIITKMTL
Sbjct: 110 -----------YQLNDPAYRKNATRDATATLKAWLNEHRKNPYPTKGEKIMLAIITKMTL 158
Query: 172 TQVSTWFANARRRLKKENKMTWAPRSRTDEEGNAYGSEREEEDEEEDEEDGKRELELEEE 231
TQVSTWFANARRRLKKENKMTWAPR+++++E G +DE D+ E E+E
Sbjct: 159 TQVSTWFANARRRLKKENKMTWAPRNKSEDEDEDEGDATRSKDESPDKAQEGTETSAEDE 218
Query: 232 ELGGEEEDTGGEGLADDDEDEEIDLENLDGAATEPELSLAGAARRD--GDLGLGPISDSK 289
+ + L D E D E L A +P L +G+ +D DL +
Sbjct: 219 GI-----SLHVDSLTDHSCSAESDGEKLPCRAGDP-LCESGSECKDKYDDL------EDD 266
Query: 290 NSDSEDSSEGLEDRPLPVLSL------AP--APPPVAVASPSLPSPPVS-LDPCAPAPAP 340
D E+ GL P PV S AP +PPP A +P S P AP PA
Sbjct: 267 EDDDEEGERGLAP-PKPVTSSPLTGLEAPLLSPPPEAAPRGGRKTPQGSRTSPGAPPPA- 324
Query: 341 ASALQKPKIWSLAETATSPDNPRRSPPGAGGSPPG--AAVAPSALQLSPAAAAAAAHRLV 398
KPK+WSLAE ATS PG G PPG AA AP++ P + A L+
Sbjct: 325 ----SKPKLWSLAEIATSDLKQPSLGPGCG--PPGLPAAAAPASTGAPPGGSPYPASPLL 378
Query: 399 SAPLGKFPAWTNRPFPGPPPGPRLHPLSLLGSAPPHLLGLPGAAGHPAAAAAFARPAEPE 458
PL + PF G +L G LL AA P A A A +
Sbjct: 379 GRPL-----YYTSPFYGNYTNYGNLNAALQGQG---LLRYNSAAAAPGEALHTAPKAASD 430
Query: 459 GGTDRCSALEVEKKLLKTAFQP 480
G LE + ++P
Sbjct: 431 AGKAGAHPLESHYRSPGGGYEP 452
>gi|7705555 iroquois homeobox 4 [Homo sapiens]
Length = 519
Score = 216 bits (551), Expect = 3e-56
Identities = 172/465 (36%), Positives = 220/465 (47%), Gaps = 68/465 (14%)
Query: 1 MSFPQLGYQYIRP---LYPSERPGAAGGSGGSAGARGGLGAGAS---------------- 41
MS+PQ GY Y L + SGG A G A A
Sbjct: 1 MSYPQFGYPYSSAPQFLMATNSLSTCCESGGRTLADSGPAASAQAPVYCPVYESRLLATA 60
Query: 42 --ELNASGSLSNVLSSVYGAPYAAAAAAAAAQGYGAFLPYAAELPIFPQLGAQYELKDSP 99
ELN++ +L VYG PY + QGYG ++ Y +E F L + ++ KD
Sbjct: 61 RHELNSAAALG-----VYGGPYGGS------QGYGNYVTYGSEASAFYSLNS-FDSKDGS 108
Query: 100 GVQH----PAAAAAFPH-PHPAFYPYGQYQFGDP-SRPKNATRESTSTLKAWLNEHRKNP 153
G H PAAAA +P+ P YPY +Y D +R KNATRE+TSTLKAWL EHRKNP
Sbjct: 109 GSAHGGLAPAAAAYYPYEPALGQYPYDRYGTMDSGTRRKNATRETTSTLKAWLQEHRKNP 168
Query: 154 YPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWAPRSRTDEEGNAYGSEREEE 213
YPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTW PR++ +E Y EEE
Sbjct: 169 YPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWPPRNKCADEKRPYAEGEEEE 228
Query: 214 DEEEDEEDGKRELELEEEELGGEEEDTGGEGLADDDEDEEIDLENLDGAATEPELSLAGA 273
EE+ + + E +G EE++ L+D D+ + ++ E P SL G
Sbjct: 229 GGEEEAREEPLKSSKNAEPVGKEEKEL---ELSDLDDFDPLEAEPPACELKPPFHSLDGG 285
Query: 274 ARRDGDLGLGPISDSKNS--------DSEDSSEGLEDRPLPVLSLA--PAPPPVAVASPS 323
R GP+ ++ + E LE + S A P P P A P
Sbjct: 286 LERVPAAPDGPVKEASGALRMSLAAGGGAALDEDLERARSCLRSAAAGPEPLPGAEGGPQ 345
Query: 324 LPSPPVSLDPCAPAPAPASALQKPKIWSLAETATSPDNPRRSP-----PGAGGSPPGAAV 378
+ + PA A A KP+IWSLA TAT+ S P G A
Sbjct: 346 VCEAKLGF---VPAGASAGLEAKPRIWSLAHTATAAAAAATSLSQTEFPSCMLKRQGPA- 401
Query: 379 APSALQLSPAAA-------AAAAHRLVSAPLGKFPAWTNRPFPGP 416
AP+A+ +PA + + A R +P+ W + F P
Sbjct: 402 APAAVSSAPATSPSVALPHSGALDRHQDSPVTSLRNWVDGVFHDP 446
>gi|42544241 iroquois homeobox protein 6 [Homo sapiens]
Length = 446
Score = 202 bits (515), Expect = 4e-52
Identities = 156/378 (41%), Positives = 192/378 (50%), Gaps = 81/378 (21%)
Query: 36 LGAGASELNASGSLSNVLSSVYGAPYAAAAAAAAAQGYGAFLPYAAELP-IFPQLGAQYE 94
LG+ EL A+ +YGAPYAAAAAA Q Y +LPY+ E P ++ L QYE
Sbjct: 57 LGSARPELGAA-------LGIYGAPYAAAAAA---QSYPGYLPYSPEPPSLYGALNPQYE 106
Query: 95 LKDSPGVQHPAAAAAFPHPHPAFYPY----GQYQF--------GDPSRPKNATRESTSTL 142
K++ G + ++ P A+YPY GQYQ+ R KNATRE+TSTL
Sbjct: 107 FKEAAG----SFTSSLAQPG-AYYPYERTLGQYQYERYGAVELSGAGRRKNATRETTSTL 161
Query: 143 KAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWAPRSRTDEE 202
KAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWAP+++ EE
Sbjct: 162 KAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWAPKNKGGEE 221
Query: 203 GNAYGSERE---------EEDEEEDEEDGKRELELEEEELGGEEEDTGGEGLADDDEDEE 253
A G E + +E E G R +LE+ E EEE ++ EDEE
Sbjct: 222 RKAEGGEEDSLGCLTADTKEVTASQEARGLRLSDLEDLEEEEEEE--------EEAEDEE 273
Query: 254 IDLENLDGAA--TEPELSLAG--AARRDGDLGLGPISDSKNSDSEDSSEGLEDRPLPVLS 309
+ D + SL G AA R+G L + S + G E+ LS
Sbjct: 274 VVATAGDRLTEFRKGAQSLPGPCAAAREGRLERRECGLAAPRFSFNDPSGSEEADF--LS 331
Query: 310 LAPAPPPVAVASPSLPSPPVSLDPCAPAPAPASALQKPKIWSLAETATS-------PDNP 362
P + + P L+KP+IWSLA TAT+ P P
Sbjct: 332 AETGSPRLTMHYP--------------------CLEKPRIWSLAHTATASAVEGAPPARP 371
Query: 363 RRSPPGA---GGSPPGAA 377
R P G PP +A
Sbjct: 372 RPRSPECRMIPGQPPASA 389
>gi|178057337 mohawk homeobox [Homo sapiens]
Length = 352
Score = 79.7 bits (195), Expect = 6e-15
Identities = 52/137 (37%), Positives = 72/137 (52%), Gaps = 20/137 (14%)
Query: 95 LKDSPGVQHPAAAAAFPHPHPAFYPYGQYQFGDPSRPKNATRESTSTLKAWLNEHRKNPY 154
LKD+ G++H A + G + A ++ LK WL +HR NPY
Sbjct: 51 LKDNLGLRHRRTGA-------------RQNGGKVRHKRQALQDMARPLKQWLYKHRDNPY 97
Query: 155 PTKGEKIMLAIITKMTLTQVSTWFANARRRLK---KENKMTWAPRSRTDE---EGNAYGS 208
PTK EKI+LA+ ++MTL QVS WFANARRRLK ++ ++WA R + +GNA
Sbjct: 98 PTKTEKILLALGSQMTLVQVSNWFANARRRLKNTVRQPDLSWALRIKLYNKYVQGNAERL 157
Query: 209 EREEEDE-EEDEEDGKR 224
+D ED E+ R
Sbjct: 158 SVSSDDSCSEDGENPPR 174
>gi|55741677 SET domain containing 1A [Homo sapiens]
Length = 1707
Score = 67.4 bits (163), Expect = 3e-11
Identities = 70/253 (27%), Positives = 95/253 (37%), Gaps = 39/253 (15%)
Query: 195 PRSRTDEEGNAYG--------------------SEREEEDEEEDEEDGKRE-----LELE 229
P R +E G G SE++EED+EEDEED RE + E
Sbjct: 941 PPKRDEERGKTQGKHRKSFALDSEGEEASQESSSEKDEEDDEEDEEDEDREEAVDTTKKE 1000
Query: 230 EEELGGEEEDTGGEGLADDDEDEEIDLENLDGAATEPELSLAGAARRDGDLGLGPISDSK 289
E GE+E++ D D EN + +E S + ++ S S
Sbjct: 1001 TEVSDGEDEESDSSSKCSLYADS--DGENDSTSDSESSSSSSSSSSSSSSSSSSSSSSSS 1058
Query: 290 NSDSEDSSEGLEDRPLPVLSLAPAPPPVAVASPS---LPSPP-VSLDPCAPAPAPASALQ 345
S SED E E+RP + S +P P V V +P+ +P P V+ P P P ++
Sbjct: 1059 ESSSEDEEE--EERPAALPSASPPPREVPVPTPAPVEVPVPERVAGSPVTPLPEQEASPA 1116
Query: 346 KPKIWSLAETATSPDNPRRSPPGAGGSPPGAAVAPSALQLSPAAAAAAAHRLVSAPLGKF 405
+P T SP + PP PP A P SP + F
Sbjct: 1117 RP----AGPTEESPPSAPLRPPEPPAGPPAPAPRPDERPSSPIPLLPPPKK--RRKTVSF 1170
Query: 406 PAWTNRPFPGPPP 418
A P P PPP
Sbjct: 1171 SAIEVVPAPEPPP 1183
Score = 61.6 bits (148), Expect = 2e-09
Identities = 67/261 (25%), Positives = 100/261 (38%), Gaps = 62/261 (23%)
Query: 182 RRRLKKENKMTWAPRSRTDEEGNAYGSEREEEDEEEDEEDGKRE-----LELEEEELGGE 236
R + + +++ ++A S +E SE++EED+EEDEED RE + E E GE
Sbjct: 948 RGKTQGKHRKSFALDSEGEEASQESSSEKDEEDDEEDEEDEDREEAVDTTKKETEVSDGE 1007
Query: 237 EEDTGGEGLADDDEDEEIDLENLDGAATEPELSLAGAARRDGDLGLGPISDSKNSDSEDS 296
+E++ D D EN + +E S + ++ S S S SED
Sbjct: 1008 DEESDSSSKCSLYADS--DGENDSTSDSESSSSSSSSSSSSSSSSSSSSSSSSESSSEDE 1065
Query: 297 SEGLEDRPLPVLSLAPAPPPVAV--------------------------ASPSLPSPPVS 330
E E+RP + S +P P V V ASP+ P+ P
Sbjct: 1066 EE--EERPAALPSASPPPREVPVPTPAPVEVPVPERVAGSPVTPLPEQEASPARPAGPTE 1123
Query: 331 --------------LDPCAPAP-------APASALQKPK------IWSLAETATSPDNPR 363
P APAP +P L PK +S E +P+ P
Sbjct: 1124 ESPPSAPLRPPEPPAGPPAPAPRPDERPSSPIPLLPPPKKRRKTVSFSAIEVVPAPEPPP 1183
Query: 364 RSPPGAGGSPPGAAVAPSALQ 384
+PP A P + AP ++
Sbjct: 1184 ATPPQAKFPGPASRKAPRGVE 1204
Score = 42.0 bits (97), Expect = 0.001
Identities = 57/205 (27%), Positives = 79/205 (38%), Gaps = 29/205 (14%)
Query: 229 EEEELGGEEEDTGGEGLADDDEDE---EIDLENLDGAATEPELSLAGAARRDGDLGLGPI 285
EE GG G L +++E E E+DL L A P ARR G L +
Sbjct: 1223 EEVSRGGRSRAGGRGRLTEEEEAEPGTEVDLAVLADLALTP-------ARR-GLPALPAV 1274
Query: 286 SDSKNSDSEDSSEGLEDRPLPVLSLAPAPPPVAVASPSLPSPPVSLDPCAPAPAPAS--- 342
DS+ +++ D +E RP P+LS A+A P P +L P P PAPA+
Sbjct: 1275 EDSEATETSDEAE----RPRPLLSHILLEHNYALAVKPTPPAP-ALRPPEPVPAPAALFS 1329
Query: 343 -----ALQKPKIWSLAETATSPD--NPRRSPPGAGGSPPGAAVAPSALQLSPAAAAAAAH 395
L+ P++ P +R G G + S ++ A
Sbjct: 1330 SPADEVLEAPEVVVAEAEEPKPQQLQQQREEGEEEGEEEGEEEEEESSDSSSSSDGEGAL 1389
Query: 396 RLVSAPLGKFPAWTNRPFPGPPPGP 420
R S + A RP P PPP P
Sbjct: 1390 RRRSL---RSHARRRRPPPPPPPPP 1411
Score = 41.6 bits (96), Expect = 0.002
Identities = 39/127 (30%), Positives = 48/127 (37%), Gaps = 11/127 (8%)
Query: 312 PAPPPVAVASPSLPSPPVSLDPCAPAPAPASALQKPKIWSLAETATSPDNPRRSPPGAGG 371
P PP A A+ +P S +P A +P + Q A +S D+ S GG
Sbjct: 538 PCTPPPAPANFEDVAPTGSGEPGATRESPKANGQNQ-----ASPCSSGDDMEISDDDRGG 592
Query: 372 SPPGAAVAPSALQLSPAAAAAAAHRLVSAPLG---KFPAWTNRPFPGPPPGPRLHPLSLL 428
SPP A P P L S PLG PA+ P P PP P P
Sbjct: 593 SPPPAPTPPQQPPPPPPPPPPPPPYLASLPLGYPPHQPAYLLPPRPDGPPPPEYPPPP-- 650
Query: 429 GSAPPHL 435
PPH+
Sbjct: 651 -PPPPHI 656
Score = 31.2 bits (69), Expect = 2.3
Identities = 14/33 (42%), Positives = 19/33 (57%)
Query: 212 EEDEEEDEEDGKRELELEEEELGGEEEDTGGEG 244
++ EE EE+G+ E E EEEE + GEG
Sbjct: 1355 QQQREEGEEEGEEEGEEEEEESSDSSSSSDGEG 1387
Score = 30.0 bits (66), Expect = 5.1
Identities = 29/126 (23%), Positives = 44/126 (34%), Gaps = 5/126 (3%)
Query: 214 DEEEDEEDGKRELELEEEELGGEEEDTGGEGLADDDEDEEIDLENLDGAATEPELSLAGA 273
D EE+EE+ + L + G E G G + E++ + + +
Sbjct: 509 DTEEEEENSS--MVLGARDTGSEVPSGSGHGPCTPPP-APANFEDVAPTGSGEPGATRES 565
Query: 274 ARRDGDLGLGPISDSKNSDSEDSSEGLEDRPLPV--LSLAPAPPPVAVASPSLPSPPVSL 331
+ +G P S + + D G P P P PPP P L S P+
Sbjct: 566 PKANGQNQASPCSSGDDMEISDDDRGGSPPPAPTPPQQPPPPPPPPPPPPPYLASLPLGY 625
Query: 332 DPCAPA 337
P PA
Sbjct: 626 PPHQPA 631
>gi|55750053 atrophin-1 [Homo sapiens]
Length = 1190
Score = 66.2 bits (160), Expect = 6e-11
Identities = 81/357 (22%), Positives = 122/357 (34%), Gaps = 33/357 (9%)
Query: 172 TQVSTWFANARRRLKKENKMTWAPRSRTDEEGNAYGSEREEEDEEEDEEDGKRELELEEE 231
T S A R+ K+ ++ A + +++G + E +E + K E EL
Sbjct: 40 TSSSDGKAEKSRQTAKKARVEEASTPKVNKQGRSEEISESESEETNAPKKTKTEQELPRP 99
Query: 232 ELGGEEEDTGGEGLADDDEDEEIDLENLDGAATEPELSLAGAARRDGDLGLG-------- 283
+ + + G L DD + D++ D +T P + G+ D D G
Sbjct: 100 QSPSDLDSLDGRSLNDDGSSDPRDIDQ-DNRSTSPSIYSPGSVENDSDSSSGLSQGPARP 158
Query: 284 --------PISDSKNSDSEDSSEGLEDRP--LPVLSLAPAPPPVA---VASPSLPSPPVS 330
P +S E P P AP PP + A P P P
Sbjct: 159 YHPPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQ 218
Query: 331 LDPCAPAPAPASALQKPKIWSLAETATSPDNPRRSPPGAGGSPPGAAVAPSALQLSPAAA 390
L P + PK A + P+ ++ PP ++ A A P
Sbjct: 219 LYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTT 278
Query: 391 AAAAHRLVSAPL-GKFPAWTNRPFPGPPPGPRLHPLSLLGSAPPHLLGLPGAAGHPAAAA 449
L SAP FP T P PP P L PL+ ++PP LG GH +
Sbjct: 279 PVGGGNLPSAPPPANFPHVT----PNLPPPPALRPLNNASASPPG-LGAQPLPGHLPSPH 333
Query: 450 AFAR-----PAEPEGGTDRCSALEVEKKLLKTAFQPVPRRPQNHLDAALVLSALSSS 501
A + P PE G + +A P R P + ++ ++ SSS
Sbjct: 334 AMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSS 390
Score = 38.9 bits (89), Expect = 0.011
Identities = 49/179 (27%), Positives = 64/179 (35%), Gaps = 19/179 (10%)
Query: 284 PISDSKNSDSEDSSEGLEDRPLPVLSLAPAPPPVAVASPSLPSPPVSLDPCAPAPAPASA 343
P+S S NS S S P +P+ P P P P V+ + A+
Sbjct: 567 PVSSSSNSSSSTSQGSY-----PCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATV 621
Query: 344 LQKPKIWSLAETATSPDNPRRSP-PGA--GGSPPG--AAVAPSALQLSPAAAAAAAHRLV 398
P + A P +R+P PGA +PPG PS +P +R
Sbjct: 622 ASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTP-----PGYRGT 676
Query: 399 SAPLGKFPAWTNRPFPGPPPGPRLHPLSLLGSAPPHLLGLPGAAGHPAAAAAFAR-PAE 456
S P G P GP P P P L PP A+G P +A + PAE
Sbjct: 677 SPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPP---PAAPASGPPLSATQIKQEPAE 732
Score = 34.7 bits (78), Expect = 0.21
Identities = 25/74 (33%), Positives = 34/74 (45%), Gaps = 10/74 (13%)
Query: 306 PVLSLAPAPPPVAVASPSLPSPPVSLDPCAPAPAPASAL-QKPKIWSLAETATSPDNPRR 364
P + P PP PSLP PP + P + P A+ + Q+P AE +P++P
Sbjct: 690 PTVGPGPLPPAGPSGLPSLPPPPAA--PASGPPLSATQIKQEP-----AEEYETPESP-- 740
Query: 365 SPPGAGGSPPGAAV 378
PP SPP V
Sbjct: 741 VPPARSPSPPPKVV 754
Score = 33.5 bits (75), Expect = 0.46
Identities = 38/150 (25%), Positives = 62/150 (41%), Gaps = 18/150 (12%)
Query: 299 GLEDRPLPVLSLAPAPPPVAVASPSLPSPPVSLDPCAPAPAPASALQKPKIWSLAETATS 358
GL P +LAP+P + AS S P+PP+ + + + A+A S + ++ S
Sbjct: 341 GLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSS---SSSSSSAS 397
Query: 359 PDNPRRSPPGAGGSPPGAAVAPSALQLSPAAAAAAAHRLVSAPLGKFPAWTNRPFPGPPP 418
P ++ P S P + P++L +S L S + W+ P P PP
Sbjct: 398 PFPASQALP----SYPHSFPPPTSLSVSNQPPKYTQPSLPSQAV-----WSQGPPPPPPY 448
Query: 419 GPRLHPLSLLGSAPPHLLGLPGAAGHPAAA 448
G LL ++ H P + G + A
Sbjct: 449 G------RLLANSNAHPGPFPPSTGAQSTA 472
>gi|55750041 atrophin-1 [Homo sapiens]
Length = 1190
Score = 66.2 bits (160), Expect = 6e-11
Identities = 81/357 (22%), Positives = 122/357 (34%), Gaps = 33/357 (9%)
Query: 172 TQVSTWFANARRRLKKENKMTWAPRSRTDEEGNAYGSEREEEDEEEDEEDGKRELELEEE 231
T S A R+ K+ ++ A + +++G + E +E + K E EL
Sbjct: 40 TSSSDGKAEKSRQTAKKARVEEASTPKVNKQGRSEEISESESEETNAPKKTKTEQELPRP 99
Query: 232 ELGGEEEDTGGEGLADDDEDEEIDLENLDGAATEPELSLAGAARRDGDLGLG-------- 283
+ + + G L DD + D++ D +T P + G+ D D G
Sbjct: 100 QSPSDLDSLDGRSLNDDGSSDPRDIDQ-DNRSTSPSIYSPGSVENDSDSSSGLSQGPARP 158
Query: 284 --------PISDSKNSDSEDSSEGLEDRP--LPVLSLAPAPPPVA---VASPSLPSPPVS 330
P +S E P P AP PP + A P P P
Sbjct: 159 YHPPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQ 218
Query: 331 LDPCAPAPAPASALQKPKIWSLAETATSPDNPRRSPPGAGGSPPGAAVAPSALQLSPAAA 390
L P + PK A + P+ ++ PP ++ A A P
Sbjct: 219 LYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTT 278
Query: 391 AAAAHRLVSAPL-GKFPAWTNRPFPGPPPGPRLHPLSLLGSAPPHLLGLPGAAGHPAAAA 449
L SAP FP T P PP P L PL+ ++PP LG GH +
Sbjct: 279 PVGGGNLPSAPPPANFPHVT----PNLPPPPALRPLNNASASPPG-LGAQPLPGHLPSPH 333
Query: 450 AFAR-----PAEPEGGTDRCSALEVEKKLLKTAFQPVPRRPQNHLDAALVLSALSSS 501
A + P PE G + +A P R P + ++ ++ SSS
Sbjct: 334 AMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSS 390
Score = 38.9 bits (89), Expect = 0.011
Identities = 49/179 (27%), Positives = 64/179 (35%), Gaps = 19/179 (10%)
Query: 284 PISDSKNSDSEDSSEGLEDRPLPVLSLAPAPPPVAVASPSLPSPPVSLDPCAPAPAPASA 343
P+S S NS S S P +P+ P P P P V+ + A+
Sbjct: 567 PVSSSSNSSSSTSQGSY-----PCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATV 621
Query: 344 LQKPKIWSLAETATSPDNPRRSP-PGA--GGSPPG--AAVAPSALQLSPAAAAAAAHRLV 398
P + A P +R+P PGA +PPG PS +P +R
Sbjct: 622 ASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTP-----PGYRGT 676
Query: 399 SAPLGKFPAWTNRPFPGPPPGPRLHPLSLLGSAPPHLLGLPGAAGHPAAAAAFAR-PAE 456
S P G P GP P P P L PP A+G P +A + PAE
Sbjct: 677 SPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPP---PAAPASGPPLSATQIKQEPAE 732
Score = 34.7 bits (78), Expect = 0.21
Identities = 25/74 (33%), Positives = 34/74 (45%), Gaps = 10/74 (13%)
Query: 306 PVLSLAPAPPPVAVASPSLPSPPVSLDPCAPAPAPASAL-QKPKIWSLAETATSPDNPRR 364
P + P PP PSLP PP + P + P A+ + Q+P AE +P++P
Sbjct: 690 PTVGPGPLPPAGPSGLPSLPPPPAA--PASGPPLSATQIKQEP-----AEEYETPESP-- 740
Query: 365 SPPGAGGSPPGAAV 378
PP SPP V
Sbjct: 741 VPPARSPSPPPKVV 754
Score = 33.5 bits (75), Expect = 0.46
Identities = 38/150 (25%), Positives = 62/150 (41%), Gaps = 18/150 (12%)
Query: 299 GLEDRPLPVLSLAPAPPPVAVASPSLPSPPVSLDPCAPAPAPASALQKPKIWSLAETATS 358
GL P +LAP+P + AS S P+PP+ + + + A+A S + ++ S
Sbjct: 341 GLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSS---SSSSSSAS 397
Query: 359 PDNPRRSPPGAGGSPPGAAVAPSALQLSPAAAAAAAHRLVSAPLGKFPAWTNRPFPGPPP 418
P ++ P S P + P++L +S L S + W+ P P PP
Sbjct: 398 PFPASQALP----SYPHSFPPPTSLSVSNQPPKYTQPSLPSQAV-----WSQGPPPPPPY 448
Query: 419 GPRLHPLSLLGSAPPHLLGLPGAAGHPAAA 448
G LL ++ H P + G + A
Sbjct: 449 G------RLLANSNAHPGPFPPSTGAQSTA 472
>gi|24497556 homeobox A7 [Homo sapiens]
Length = 230
Score = 61.2 bits (147), Expect = 2e-09
Identities = 67/223 (30%), Positives = 93/223 (41%), Gaps = 17/223 (7%)
Query: 14 LYPSERPGAAGGSGGSAGARGGLGAGASELNASGSLSNVLSSVYGAPYAAAAAAAAAQGY 73
L+ + P + + S + G GAGA G L NV S +Y +P+A+ A Y
Sbjct: 20 LFQNAEPTSCSFAPNSQRSGYGAGAGAFASTVPG-LYNVNSPLYQSPFASGYGLGA-DAY 77
Query: 74 GAFLPYAAELPIFPQLGAQYEL----KDSPGVQHPAAAAAFPHPHPAFYPYGQYQFGDPS 129
G LP A+ P L + K G H AA A F YP+ + D
Sbjct: 78 GN-LPCASYDQNIPGLCSDLAKGACDKTDEGALHGAAEANF-----RIYPWMRSSGPDRK 131
Query: 130 RPKNA-TRESTSTLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKE 188
R + TR T L+ E N Y T+ +I +A +T Q+ WF N R + KKE
Sbjct: 132 RGRQTYTRYQTLELE---KEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKE 188
Query: 189 NKMTWAPRSRTDEEGNAYGSEREEEDEEEDEEDGKRELELEEE 231
+K P + EG + ++ DEED E E EEE
Sbjct: 189 HKDE-GPTAAAAPEGAVPSAAATAAADKADEEDDDEEEEDEEE 230
>gi|116812644 PBX/knotted 1 homeobox 2 [Homo sapiens]
Length = 472
Score = 59.7 bits (143), Expect = 6e-09
Identities = 40/158 (25%), Positives = 69/158 (43%), Gaps = 28/158 (17%)
Query: 136 RESTSTLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRL---------- 185
+ +T+ +++WL +H +PYPT+ EK +A T +TL QV+ WF NARRR+
Sbjct: 297 KHATNIMRSWLFQHLMHPYPTEDEKRQIAAQTNLTLLQVNNWFINARRRILQPMLDASNP 356
Query: 186 -----KKENKMTWAPRSR----------TDEEGNAYGSEREEE---DEEEDEEDGKRELE 227
K+ K P R ++G A G+ + D + +
Sbjct: 357 DPAPKAKKIKSQHRPTQRFWPNSIAAGVLQQQGGAPGTNPDGSINLDNLQSLSSDSATMA 416
Query: 228 LEEEELGGEEEDTGGEGLADDDEDEEIDLENLDGAATE 265
+++ + ++ G D+DE EE + E L+ E
Sbjct: 417 MQQAMMAAHDDSLDGTEEEDEDEMEEEEEEELEEEVDE 454
>gi|24431933 reticulon 4 isoform B [Homo sapiens]
Length = 373
Score = 58.2 bits (139), Expect = 2e-08
Identities = 58/198 (29%), Positives = 77/198 (38%), Gaps = 48/198 (24%)
Query: 206 YGSEREEEDEEEDEEDGKRELELEEEELGGEEEDTGGEGLADDDEDEEIDLENLDGAATE 265
Y RE EDEEE+EE +++EDE+ DLE L+ +
Sbjct: 25 YQFVREPEDEEEEEE--------------------------EEEEDEDEDLEELEVLERK 58
Query: 266 PELSLAGAARRDGDLGLGPISDSKNSDSEDSSEGLEDRPLPVLSLAPAPPPVAVASPSLP 325
P L+ A P+ D N + G PLP APP PS
Sbjct: 59 PAAGLSAAPVPTAPAAGAPLMDFGNDFVPPAPRG----PLPA-----APPVAPERQPSWD 109
Query: 326 SPPVSLDPCAPAPAPASALQKPKIWSLAETATSPDNPRRSPPGAGGSPPGAAVAPSA--L 383
PVS AP+P A+A+ K+ + P R PP PP A+V+P A +
Sbjct: 110 PSPVSSTVPAPSPLSAAAVSPSKL------PEDDEPPARPPP-----PPPASVSPQAEPV 158
Query: 384 QLSPAAAAAAAHRLVSAP 401
PA A AA +AP
Sbjct: 159 WTPPAPAPAAPPSTPAAP 176
>gi|47519490 reticulon 4 isoform D [Homo sapiens]
Length = 392
Score = 58.2 bits (139), Expect = 2e-08
Identities = 58/198 (29%), Positives = 77/198 (38%), Gaps = 48/198 (24%)
Query: 206 YGSEREEEDEEEDEEDGKRELELEEEELGGEEEDTGGEGLADDDEDEEIDLENLDGAATE 265
Y RE EDEEE+EE +++EDE+ DLE L+ +
Sbjct: 25 YQFVREPEDEEEEEE--------------------------EEEEDEDEDLEELEVLERK 58
Query: 266 PELSLAGAARRDGDLGLGPISDSKNSDSEDSSEGLEDRPLPVLSLAPAPPPVAVASPSLP 325
P L+ A P+ D N + G PLP APP PS
Sbjct: 59 PAAGLSAAPVPTAPAAGAPLMDFGNDFVPPAPRG----PLPA-----APPVAPERQPSWD 109
Query: 326 SPPVSLDPCAPAPAPASALQKPKIWSLAETATSPDNPRRSPPGAGGSPPGAAVAPSA--L 383
PVS AP+P A+A+ K+ + P R PP PP A+V+P A +
Sbjct: 110 PSPVSSTVPAPSPLSAAAVSPSKL------PEDDEPPARPPP-----PPPASVSPQAEPV 158
Query: 384 QLSPAAAAAAAHRLVSAP 401
PA A AA +AP
Sbjct: 159 WTPPAPAPAAPPSTPAAP 176
>gi|24431935 reticulon 4 isoform A [Homo sapiens]
Length = 1192
Score = 58.2 bits (139), Expect = 2e-08
Identities = 58/198 (29%), Positives = 77/198 (38%), Gaps = 48/198 (24%)
Query: 206 YGSEREEEDEEEDEEDGKRELELEEEELGGEEEDTGGEGLADDDEDEEIDLENLDGAATE 265
Y RE EDEEE+EE +++EDE+ DLE L+ +
Sbjct: 25 YQFVREPEDEEEEEE--------------------------EEEEDEDEDLEELEVLERK 58
Query: 266 PELSLAGAARRDGDLGLGPISDSKNSDSEDSSEGLEDRPLPVLSLAPAPPPVAVASPSLP 325
P L+ A P+ D N + G PLP APP PS
Sbjct: 59 PAAGLSAAPVPTAPAAGAPLMDFGNDFVPPAPRG----PLPA-----APPVAPERQPSWD 109
Query: 326 SPPVSLDPCAPAPAPASALQKPKIWSLAETATSPDNPRRSPPGAGGSPPGAAVAPSA--L 383
PVS AP+P A+A+ K+ + P R PP PP A+V+P A +
Sbjct: 110 PSPVSSTVPAPSPLSAAAVSPSKL------PEDDEPPARPPP-----PPPASVSPQAEPV 158
Query: 384 QLSPAAAAAAAHRLVSAP 401
PA A AA +AP
Sbjct: 159 WTPPAPAPAAPPSTPAAP 176
>gi|28178843 TG-interacting factor isoform a [Homo sapiens]
Length = 401
Score = 57.4 bits (137), Expect = 3e-08
Identities = 28/60 (46%), Positives = 36/60 (60%)
Query: 126 GDPSRPKNATRESTSTLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRL 185
G R N +ES L+ WL EHR N YP++ EK +L+ T ++ QV WF NARRRL
Sbjct: 163 GKRRRRGNLPKESVQILRDWLYEHRYNAYPSEQEKALLSQQTHLSTLQVCNWFINARRRL 222
>gi|4507473 TG-interacting factor isoform c [Homo sapiens]
Length = 272
Score = 57.4 bits (137), Expect = 3e-08
Identities = 28/60 (46%), Positives = 36/60 (60%)
Query: 126 GDPSRPKNATRESTSTLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRL 185
G R N +ES L+ WL EHR N YP++ EK +L+ T ++ QV WF NARRRL
Sbjct: 34 GKRRRRGNLPKESVQILRDWLYEHRYNAYPSEQEKALLSQQTHLSTLQVCNWFINARRRL 93
>gi|28178855 TG-interacting factor isoform d [Homo sapiens]
Length = 252
Score = 57.4 bits (137), Expect = 3e-08
Identities = 28/60 (46%), Positives = 36/60 (60%)
Query: 126 GDPSRPKNATRESTSTLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRL 185
G R N +ES L+ WL EHR N YP++ EK +L+ T ++ QV WF NARRRL
Sbjct: 14 GKRRRRGNLPKESVQILRDWLYEHRYNAYPSEQEKALLSQQTHLSTLQVCNWFINARRRL 73
>gi|28178853 TG-interacting factor isoform d [Homo sapiens]
Length = 252
Score = 57.4 bits (137), Expect = 3e-08
Identities = 28/60 (46%), Positives = 36/60 (60%)
Query: 126 GDPSRPKNATRESTSTLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRL 185
G R N +ES L+ WL EHR N YP++ EK +L+ T ++ QV WF NARRRL
Sbjct: 14 GKRRRRGNLPKESVQILRDWLYEHRYNAYPSEQEKALLSQQTHLSTLQVCNWFINARRRL 73
>gi|28178851 TG-interacting factor isoform d [Homo sapiens]
Length = 252
Score = 57.4 bits (137), Expect = 3e-08
Identities = 28/60 (46%), Positives = 36/60 (60%)
Query: 126 GDPSRPKNATRESTSTLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRL 185
G R N +ES L+ WL EHR N YP++ EK +L+ T ++ QV WF NARRRL
Sbjct: 14 GKRRRRGNLPKESVQILRDWLYEHRYNAYPSEQEKALLSQQTHLSTLQVCNWFINARRRL 73
>gi|28178857 TG-interacting factor isoform d [Homo sapiens]
Length = 252
Score = 57.4 bits (137), Expect = 3e-08
Identities = 28/60 (46%), Positives = 36/60 (60%)
Query: 126 GDPSRPKNATRESTSTLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRL 185
G R N +ES L+ WL EHR N YP++ EK +L+ T ++ QV WF NARRRL
Sbjct: 14 GKRRRRGNLPKESVQILRDWLYEHRYNAYPSEQEKALLSQQTHLSTLQVCNWFINARRRL 73
>gi|28178849 TG-interacting factor isoform c [Homo sapiens]
Length = 272
Score = 57.4 bits (137), Expect = 3e-08
Identities = 28/60 (46%), Positives = 36/60 (60%)
Query: 126 GDPSRPKNATRESTSTLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRL 185
G R N +ES L+ WL EHR N YP++ EK +L+ T ++ QV WF NARRRL
Sbjct: 34 GKRRRRGNLPKESVQILRDWLYEHRYNAYPSEQEKALLSQQTHLSTLQVCNWFINARRRL 93
>gi|28178845 TG-interacting factor isoform b [Homo sapiens]
Length = 286
Score = 57.4 bits (137), Expect = 3e-08
Identities = 28/60 (46%), Positives = 36/60 (60%)
Query: 126 GDPSRPKNATRESTSTLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRL 185
G R N +ES L+ WL EHR N YP++ EK +L+ T ++ QV WF NARRRL
Sbjct: 48 GKRRRRGNLPKESVQILRDWLYEHRYNAYPSEQEKALLSQQTHLSTLQVCNWFINARRRL 107
>gi|28866955 PBX/knotted 1 homeobox 1 [Homo sapiens]
Length = 436
Score = 56.6 bits (135), Expect = 5e-08
Identities = 23/50 (46%), Positives = 36/50 (72%)
Query: 136 RESTSTLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRL 185
+ +T+ +++WL +H +PYPT+ EK +A T +TL QV+ WF NARRR+
Sbjct: 268 KHATNVMRSWLFQHIGHPYPTEDEKKQIAAQTNLTLLQVNNWFINARRRI 317
>gi|12056969 homeobox C8 [Homo sapiens]
Length = 242
Score = 56.2 bits (134), Expect = 7e-08
Identities = 28/70 (40%), Positives = 41/70 (58%)
Query: 152 NPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWAPRSRTDEEGNAYGSERE 211
NPY T+ +I ++ +T QV WF N R + KKEN P +R +E+ G+E E
Sbjct: 171 NPYLTRKRRIEVSHALGLTERQVKIWFQNRRMKWKKENNKDKLPGARDEEKVEEEGNEEE 230
Query: 212 EEDEEEDEED 221
E++EEE EE+
Sbjct: 231 EKEEEEKEEN 240
>gi|210032580 SET domain containing 1B [Homo sapiens]
Length = 1923
Score = 56.2 bits (134), Expect = 7e-08
Identities = 79/284 (27%), Positives = 107/284 (37%), Gaps = 47/284 (16%)
Query: 188 ENKMTWAPRSRTDEEGNAYGSEREEEDEEE--DEED----GKRELELEEEE--------- 232
E+ +P S DEE E EEE+EEE EE G + E + EE
Sbjct: 1122 ESSSESSPSSSEDEEEVVAREEEEEEEEEEMVAEESMASAGPEDFEQDGEEAALAPGAPA 1181
Query: 233 ---LGGEEE-DTGGEGLADDDEDEEIDLENLDGAATEP----ELSLAGAARRDGDLGLGP 284
LG EEE D E +A ++ +D L EP E ++G + L P
Sbjct: 1182 VDSLGMEEEVDIETEAVAPEERPSMLDEPPLPVGVEEPADSREPPEEPGLSQEGAMLLSP 1241
Query: 285 ISDSKN-------SDSEDSSEGLEDRPLPVLSL-----APAPPPVAVASPSLPSPPVSLD 332
+K S LE P P + L P PPP PS P P + D
Sbjct: 1242 EPPAKEVEARPPLSPERAPEHDLEVEPEPPMMLPLPLQPPLPPPRPPRPPSPPPEPETTD 1301
Query: 333 PCAPA--PAPASALQKPKIWSLA-------ETATSPDNPRRSPPGAGGSPPGAAVAPSAL 383
P+ P P + P L T T P P PP +GGS G +++ +
Sbjct: 1302 ASHPSVPPEPLAEDHPPHTPGLCGSLAKSQSTETVPATPGGEPPLSGGS-SGLSLSSPQV 1360
Query: 384 QLSPAAAAAAAHRLVSAPLGKFPA--WTNRPFPGPPPGPRLHPL 425
SP + A + L S L + P ++ P P GP L P+
Sbjct: 1361 PGSPFSYPAPSPSLSSGGLPRTPGRDFSFTPTFSEPSGPLLLPV 1404
Score = 50.1 bits (118), Expect = 5e-06
Identities = 70/297 (23%), Positives = 106/297 (35%), Gaps = 50/297 (16%)
Query: 209 EREEEDEEEDEEDGKRELELEEEELGGEEEDTGGEGLADDDEDEEIDLENLDGAATEPEL 268
E EE +EEE+EED + + +E ++EDT ++ DE + + E + ++ E
Sbjct: 1050 EEEEAEEEEEEEDDDDDDSDDRDESENDDEDTALSEASEKDEGDSDEEETVSIVTSKAEA 1109
Query: 269 SLAGAARRDGDLGLGPISDSKNSDSEDSSEGL---------EDRPLPVLSLAPAPP---- 315
+ + + + S+S S SED E + E+ + S+A A P
Sbjct: 1110 TSSSESSESSEFESS--SESSPSSSEDEEEVVAREEEEEEEEEEMVAEESMASAGPEDFE 1167
Query: 316 ---PVAVASPSLPS---------PPVSLDPCAPAPAPASALQKPKIWSLAETATS---PD 360
A +P P+ + + AP P+ + P + E A S P+
Sbjct: 1168 QDGEEAALAPGAPAVDSLGMEEEVDIETEAVAPEERPSMLDEPPLPVGVEEPADSREPPE 1227
Query: 361 NPRRSPPGAG--GSPPGAAVAPSALQLSPAAAAAAAHRLVSAPLGKFPAWTNRPF----- 413
P S GA P A + LSP A + P P P
Sbjct: 1228 EPGLSQEGAMLLSPEPPAKEVEARPPLSPERAPEHDLEVEPEPPMMLPLPLQPPLPPPRP 1287
Query: 414 ---PGPPPGPR--------LHPLSLLGSAPPHLLGLPGAAGHPAAAAAFARPAEPEG 459
P PPP P + P L PPH GL G+ + PA P G
Sbjct: 1288 PRPPSPPPEPETTDASHPSVPPEPLAEDHPPHTPGLCGSLAKSQSTETV--PATPGG 1342
Score = 49.7 bits (117), Expect = 6e-06
Identities = 71/275 (25%), Positives = 99/275 (36%), Gaps = 32/275 (11%)
Query: 193 WAPRSRTDEEGNAYGSEREEEDEEEDEEDGKRELELEEEELGGEEEDTGGEGLADDDEDE 252
W+P S ++ D D + E+ L+E+ T L + D D
Sbjct: 472 WSPEPCDSPGTPTLESSPAGPEKPHDSLDSRIEMLLKEQR-------TKLLFLREPDSDT 524
Query: 253 EIDLENLDGAATEPELSLAGAARRDGDLGL-GPISDSKNSDSEDSSEGLED---RPLPV- 307
E+ +E +++ +LS + G GP S S SS GLED PLP
Sbjct: 525 ELQMEGSPISSSSSQLSPLAPFGTNSQPGFRGPTPPS----SRPSSTGLEDISPTPLPDS 580
Query: 308 -------LSLAPAPPPVAVASPSLPSPPVSLDPCAPAPAPASALQKPKIWSLAE-TATSP 359
L L P PPP P P P L A + P + E +S
Sbjct: 581 DEDEELDLGLGPRPPP----EPGPPDPAGLLSQTAEVALDLVGDRTPTSEKMDEGQQSSG 636
Query: 360 DNPRRSPPGAGGSPPGAAVAPSALQLSPAAAAAAAHRLVSAPLGKFPAWTNRPFPGPPPG 419
++ S +P +A P + ++P AAA AA +++ L P P P PPP
Sbjct: 637 EDMEISDDEMPSAPITSADCPKPMVVTPGAAAVAAPSVLAPTLPLPPPPGFPPLPPPPPP 696
Query: 420 PRLHPLSLLGSAPPHLLGLPGAAGHPAAAAAFARP 454
P P G P L P PA A P
Sbjct: 697 PPPQP----GFPMPPPLPPPPPPPPPAHPAVTVPP 727
Score = 38.5 bits (88), Expect = 0.014
Identities = 52/195 (26%), Positives = 68/195 (34%), Gaps = 35/195 (17%)
Query: 238 EDTGGEGLADDDEDEEIDLENLDGAATEP-ELSLAGAARRDGDLGLG------PISDSKN 290
ED L D DEDEE+DL EP AG + ++ L P S+ +
Sbjct: 570 EDISPTPLPDSDEDEELDLGLGPRPPPEPGPPDPAGLLSQTAEVALDLVGDRTPTSEKMD 629
Query: 291 SDSEDSSEGLE----DRPLPVLSLAPAPPPV-------AVASPS---------------- 323
+ S E +E + P ++ A P P+ AVA+PS
Sbjct: 630 EGQQSSGEDMEISDDEMPSAPITSADCPKPMVVTPGAAAVAAPSVLAPTLPLPPPPGFPP 689
Query: 324 LPSPPVSLDPCAPAPAPASALQKPKIWSLAETA-TSPDNPRRSPPGAGGSPPGAAVAPSA 382
LP PP P P P P A A T P P +PPG P + P
Sbjct: 690 LPPPPPPPPPQPGFPMPPPLPPPPPPPPPAHPAVTVPPPPLPAPPGVPPPPILPPLPPFP 749
Query: 383 LQLSPAAAAAAAHRL 397
L P +H L
Sbjct: 750 PGLFPVMQVDMSHVL 764
Score = 34.7 bits (78), Expect = 0.21
Identities = 47/186 (25%), Positives = 60/186 (32%), Gaps = 48/186 (25%)
Query: 304 PLPVLSLAPAPPPVAVASPSL---------PSPPVSLDPCAPAPAPASALQKPKIWSLAE 354
PLP+ P P P+ +A P++ P PP+ P A P P
Sbjct: 1430 PLPL----PLPLPLPLALPAVLRAQARAPTPLPPLLPAPLASCPPPMKR----------- 1474
Query: 355 TATSPDNPRRSPPGAGG-------SPPGAAVAPSALQL-----SPAAAAAAAHRLVS--- 399
P PRRSPP P GAA+ L L +P + R V+
Sbjct: 1475 ---KPGRPRRSPPSMLSLDGPLVRPPAGAALGRELLLLPGQPQTPVFPSTHDPRTVTLDF 1531
Query: 400 ------APLGKFPAWTNRPFPGPPPGPRLHPLSLLGSAPPHLLGLPGAAGHPAAAAAFAR 453
AP P P P PP P P L + P PG G +
Sbjct: 1532 RNAGIPAPPPPLPPQPPPPPPPPPVEPTKLPFKELDNQWPSEAIPPGPRGRDEVTEEYME 1591
Query: 454 PAEPEG 459
A+ G
Sbjct: 1592 LAKSRG 1597
Score = 32.3 bits (72), Expect = 1.0
Identities = 39/144 (27%), Positives = 52/144 (36%), Gaps = 27/144 (18%)
Query: 304 PLPVLSLAPAPPPVAVASPSLPSPPV--SLDPCAPAPAPASALQKPKI----WS----LA 353
P P PPP A P +P PP+ L P P P + + W
Sbjct: 716 PPPAHPAVTVPPPPLPAPPGVPPPPILPPLPPFPPGLFPVMQVDMSHVLGGQWGGMPMSF 775
Query: 354 ETATSPDNPRRSPPGAGGSPPGAAVAPSALQLSPAAAAAAAHRLVSAPLGKFPAWTNRPF 413
+ T + + GA PP A A AAAA+A + V+ P + P +
Sbjct: 776 QMQTQVLSRLMTGQGACPYPPFMAAA--------AAAASAGLQFVNLPPYRGPFSLSNSG 827
Query: 414 PGP----PPGPRLHPLSLLGSAPP 433
PG PP P+ P S PP
Sbjct: 828 PGRGQHWPPLPKFDP-----SVPP 846
Score = 30.8 bits (68), Expect = 3.0
Identities = 44/186 (23%), Positives = 67/186 (36%), Gaps = 44/186 (23%)
Query: 311 APAPPPVAVASPSLPSPPVSLDPCAPAPAPASALQ---KPKIWSLAETATSPDNPRRSPP 367
APAPPP+ A P P + P P P ++++ +P E SP P
Sbjct: 431 APAPPPLPPAEPLAKEKPGT--PPGPPPPDTNSMELGGRPTFGWSPEPCDSPGTPTLESS 488
Query: 368 GAGGSPPGAAV----------------------APSALQLSPAAAAAAAHRLVSAPLGKF 405
AG P ++ + + LQ+ + ++++ +L +PL F
Sbjct: 489 PAGPEKPHDSLDSRIEMLLKEQRTKLLFLREPDSDTELQMEGSPISSSSSQL--SPLAPF 546
Query: 406 PAWTNRPFPGP-PPGPRLHPLSLLGSAPPHL----------LGL----PGAAGHPAAAAA 450
+ F GP PP R L +P L LGL P G P A
Sbjct: 547 GTNSQPGFRGPTPPSSRPSSTGLEDISPTPLPDSDEDEELDLGLGPRPPPEPGPPDPAGL 606
Query: 451 FARPAE 456
++ AE
Sbjct: 607 LSQTAE 612
>gi|149158690 HLA-B associated transcript-2 [Homo sapiens]
Length = 2157
Score = 55.8 bits (133), Expect = 9e-08
Identities = 56/208 (26%), Positives = 90/208 (43%), Gaps = 34/208 (16%)
Query: 235 GEEEDTGGEGL---ADDDEDEEIDLENLDGAATEPELSLA-GAARRDGDLGLGPISDSKN 290
G+ D GG A +DEDE ++ E+SLA ARR + + + +
Sbjct: 427 GDYPDRGGPPCKPPAPEDEDEAWRQRRKQSSS---EISLAVERARRRREEEERRMQEERR 483
Query: 291 SDSEDSSEGLEDR---PLPVLSLAPAPPPVAVASPSLPSPPVSLD---PCAPAPAPASAL 344
+ + + L+++ P L PA PP A+PS P+PP ++ P PAP PASA
Sbjct: 484 AACAEKLKRLDEKFGAPDKRLKAEPAAPP---AAPSTPAPPPAVPKELPAPPAPPPASA- 539
Query: 345 QKPKIWSLAETATSPDNPRRSPPGAGGSPPGAAVAPSALQLSPAAAAAAAHRLVSAPL-- 402
T P+ P ++PP PG A AP+ + + ++ ++ ++P+
Sbjct: 540 --------PTPETEPEEPAQAPPAQSTPTPGVAAAPTLVSGGGSTSSTSSGSFEASPVEP 591
Query: 403 ------GKFPAWTNRPFPGPPPGPRLHP 424
G P P P PP P++ P
Sbjct: 592 QLPSKEGPEPP-EEVPPPTTPPVPKVEP 618
Score = 39.3 bits (90), Expect = 0.008
Identities = 43/158 (27%), Positives = 61/158 (38%), Gaps = 19/158 (12%)
Query: 304 PLPVLSLAPAPPPVAVASP--SLPSPPVSLDPCAPAPAPASALQKPKIWS---LAETATS 358
PLP SL + S S P P P+ APA + P + S + +
Sbjct: 1937 PLPDTSLLQVRQDLPSPSDFYSTPLQPGGQSGFLPSGAPAQQMLLPMVDSQLPVVNFGSL 1996
Query: 359 PDNPRRSPPGAGGSPPGAAVAPSALQLSPAAAAAAAHRLVSAPLGKFPAWTNRPFPGPPP 418
P P +PP P G A+ P +L + P A A R++ +P RPFP
Sbjct: 1997 PPAPPPAPPPLSLLPVGPALQPPSLAVRPPPAPAT--RVLPSPA--------RPFPASLG 2046
Query: 419 GPRLHPLSLLG----SAPPHLLGLPGAAGHPAAAAAFA 452
LHP+ L LG PG++ P +F+
Sbjct: 2047 RAELHPVELKPFQDYQKLSSNLGGPGSSRTPPTGRSFS 2084
Score = 37.0 bits (84), Expect = 0.042
Identities = 69/297 (23%), Positives = 97/297 (32%), Gaps = 57/297 (19%)
Query: 209 EREEEDEEED--------EEDGKRELELEEEELGGEEEDTGGEGLADDDEDEEIDLENLD 260
E ++ D+E D E D +L+ +EE G + ++ G EG D ++
Sbjct: 314 EFDQLDQENDDGWAGAHEEVDYTEKLKFSDEEDGRDSDEEGAEGHRDS--------QSAS 365
Query: 261 GAATEPELSLAGAARRDGDLGLGPISDSKNSDS--EDSSEGLEDRPLPVLSLAPAPP--- 315
G PE DG G P S+ + ++S E P P P PP
Sbjct: 366 GEERPPE--------ADGKKGNSPNSEPPTPKTAWAETSRPPETEPGPPAPKPPLPPPHR 417
Query: 316 -PVAVASPSLPSPPVSLDPCAPAPAPA---SALQKPKIWSLAETATSPDNPRRSPPGAGG 371
P P P PC P PAP A ++ + S +E + + + RR
Sbjct: 418 GPAGNWGPPGDYPDRGGPPCKP-PAPEDEDEAWRQRRKQSSSEISLAVERARRRREEEER 476
Query: 372 SPPGAAVAPSA----------------LQLSPAAAAAAAHRLVSAPLGKFPAWTNRPFPG 415
A A L+ PAA AA AP P P P
Sbjct: 477 RMQEERRAACAEKLKRLDEKFGAPDKRLKAEPAAPPAAPS--TPAPPPAVPKELPAP-PA 533
Query: 416 PPPG----PRLHPLSLLGSAPPHLLGLPGAAGHPAAAAAFARPAEPEGGTDRCSALE 468
PPP P P + P PG A P + + G+ S +E
Sbjct: 534 PPPASAPTPETEPEEPAQAPPAQSTPTPGVAAAPTLVSGGGSTSSTSSGSFEASPVE 590
Score = 34.3 bits (77), Expect = 0.27
Identities = 24/64 (37%), Positives = 27/64 (42%), Gaps = 11/64 (17%)
Query: 302 DRPLPVL---SLAPAPPPVAVASPSLPSPPVSLDPCAPAPAPASALQKPKIWSLAETATS 358
D LPV+ SL PAPPP PP+SL P PA P S +P S
Sbjct: 1985 DSQLPVVNFGSLPPAPPPAP--------PPLSLLPVGPALQPPSLAVRPPPAPATRVLPS 2036
Query: 359 PDNP 362
P P
Sbjct: 2037 PARP 2040
Score = 30.0 bits (66), Expect = 5.1
Identities = 31/127 (24%), Positives = 42/127 (33%), Gaps = 12/127 (9%)
Query: 304 PLPVLSLAPA--PPPVAVASPSLPSPPVSLDPCAPAPA--------PASALQKPKIWSLA 353
PL +L + PA PP +AV P P+ V P P PA P L+
Sbjct: 2006 PLSLLPVGPALQPPSLAVRPPPAPATRVLPSPARPFPASLGRAELHPVELKPFQDYQKLS 2065
Query: 354 ETATSPDNPRRSPPGAGGSPPGAAVAPSALQLSPAAAAAAAHRLVSAPLGKFPAWTNRPF 413
P + R P G S + + + S A W +P+
Sbjct: 2066 SNLGGPGSSRTPPTGRSFSGLNSRLKATPSTYSGVFRTQRVDLYQQASPPDALRWIPKPW 2125
Query: 414 --PGPPP 418
GPPP
Sbjct: 2126 ERTGPPP 2132
>gi|89257348 homeo box HB9 [Homo sapiens]
Length = 401
Score = 55.8 bits (133), Expect = 9e-08
Identities = 77/305 (25%), Positives = 106/305 (34%), Gaps = 82/305 (26%)
Query: 19 RPGAAGGSGGSAGARGGLGAGASELNASGSLSNVLSSVYGAPYAAAAAAAAAQGYGAFLP 78
+PG G GG G GG G + A AAAAAAAAA G A
Sbjct: 93 KPGFLGAGGGGGGTGGGHGGPHHHAHPG-----------AAAAAAAAAAAAAAGGLALGL 141
Query: 79 YAAELPIFPQLGAQYELKDSP--GVQHPAAAAAFPHPHPAF-YPYGQYQFGDPSRPKNAT 135
+ L AQ L P G AAAAA HPA Y Y Q Q P+ P +
Sbjct: 142 HPGGAQGGAGLPAQAALYGHPVYGYSAAAAAAALAGQHPALSYSYPQVQGAHPAHPADPI 201
Query: 136 RESTST--LKAWL-------------------------------------------NEHR 150
+ T L WL ++ +
Sbjct: 202 KLGAGTFQLDQWLRASTAGMILPKMPDFNSQAQSNLLGKCRRPRTAFTSQQLLELEHQFK 261
Query: 151 KNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWAPRSRTDEE----GNAY 206
N Y ++ ++ +A +T TQV WF N R + K+ K +++ G A
Sbjct: 262 LNKYLSRPKRFEVATSLMLTETQVKIWFQNRRMKWKRSKKAKEQAAQEAEKQKGGGGGAG 321
Query: 207 GSEREEEDEEE--------DEEDGKRELELEEEELGGEEEDTGGEGLADDDEDEEIDLEN 258
EE EE D+ G+R +L + + EE D+DED+E
Sbjct: 322 KGGAEEPGAEELLGPPAPGDKGSGRRLRDLRDSD---PEE--------DEDEDDEDHFPY 370
Query: 259 LDGAA 263
+GA+
Sbjct: 371 SNGAS 375
Score = 31.6 bits (70), Expect = 1.8
Identities = 41/156 (26%), Positives = 48/156 (30%), Gaps = 25/156 (16%)
Query: 326 SPPVSLDPCAPAPAPASALQKPKIWSLAETATSPDNPRRSPPGAGGSPPGAAVAPSALQL 385
SP S P APA + P A A P P G GG G
Sbjct: 59 SPASSEPPAAPADRLRAESPSPPRLLAAHCALLP-KPGFLGAGGGGGGTGGGHGGPHHHA 117
Query: 386 SPAAAAAAAHRLVSAPLGKFPAWTNRPFPGPPPGPRLHPLSLLGSAPPHLLGLPGAAGHP 445
P AAAAAA +A G G PG G G AG P
Sbjct: 118 HPGAAAAAAAAAAAAAAGGLAL-------GLHPG-----------------GAQGGAGLP 153
Query: 446 AAAAAFARPAEPEGGTDRCSALEVEKKLLKTAFQPV 481
A AA + P +AL + L ++ V
Sbjct: 154 AQAALYGHPVYGYSAAAAAAALAGQHPALSYSYPQV 189
>gi|21735415 centromere protein B [Homo sapiens]
Length = 599
Score = 55.5 bits (132), Expect = 1e-07
Identities = 52/163 (31%), Positives = 64/163 (39%), Gaps = 44/163 (26%)
Query: 207 GSEREEEDEEEDEEDGKRELELEEEELGGEEEDTGGEGL-------------ADDDEDEE 253
G E EEE+EEE+EE+G+ E EEEE G EEE+ GGEG D DE+EE
Sbjct: 405 GEEEEEEEEEEEEEEGEGE---EEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEEE 461
Query: 254 IDLENLDGAATEPELSLAGAARRDGDLGL-----------------GPISDSKNSDSEDS 296
D E E E G G G G SDS + + +D
Sbjct: 462 ED-EESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHFLEGGEDSDSDSEEEDDE 520
Query: 297 SEGLEDR----------PLPVLSLAPAPPPVAVASPSLPSPPV 329
E ED +PV S A A+ L S P+
Sbjct: 521 EEDDEDEDDDDDEEDGDEVPVPSFGEAMAYFAMVKRYLTSFPI 563
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.130 0.384
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,418,842
Number of Sequences: 37866
Number of extensions: 1797397
Number of successful extensions: 41079
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 869
Number of HSP's successfully gapped in prelim test: 1845
Number of HSP's that attempted gapping in prelim test: 16457
Number of HSP's gapped (non-prelim): 14537
length of query: 501
length of database: 18,247,518
effective HSP length: 106
effective length of query: 395
effective length of database: 14,233,722
effective search space: 5622320190
effective search space used: 5622320190
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.