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Search of human proteins with 225735593
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|225735593 RNA polymerase II associated protein 3 isoform 2
[Homo sapiens]
(631 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|225735593 RNA polymerase II associated protein 3 isoform 2 [H... 1238 0.0
gi|225735591 RNA polymerase II associated protein 3 isoform 1 [H... 1221 0.0
gi|225735595 RNA polymerase II associated protein 3 isoform 3 [H... 903 0.0
gi|27262638 sperm associated antigen 1 [Homo sapiens] 114 4e-25
gi|27262636 sperm associated antigen 1 [Homo sapiens] 114 4e-25
gi|21361356 translocase of outer mitochondrial membrane 34 [Homo... 113 6e-25
gi|5803181 stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizi... 103 6e-22
gi|24308141 small glutamine-rich tetratricopeptide repeat (TPR)-... 96 1e-19
gi|54607135 translocase of outer mitochondrial membrane 70 homol... 93 6e-19
gi|221219053 DnaJ (Hsp40) homolog, subfamily C, member 7 isoform... 87 4e-17
gi|5453958 protein phosphatase 5, catalytic subunit [Homo sapiens] 82 1e-15
gi|4506921 small glutamine-rich tetratricopeptide [Homo sapiens] 81 3e-15
gi|90669931 tetratricopeptide repeat domain 12 [Homo sapiens] 79 1e-14
gi|4507711 tetratricopeptide repeat domain 1 [Homo sapiens] 77 6e-14
gi|224809329 FK506 binding protein 5 isoform 1 [Homo sapiens] 76 8e-14
gi|224809327 FK506 binding protein 5 isoform 1 [Homo sapiens] 76 8e-14
gi|4758384 FK506 binding protein 5 isoform 1 [Homo sapiens] 76 8e-14
gi|221219056 DnaJ (Hsp40) homolog, subfamily C, member 7 isoform... 75 2e-13
gi|4503729 FK506 binding protein 52 [Homo sapiens] 74 4e-13
gi|224028289 tetratricopeptide repeat domain 28 [Homo sapiens] 70 6e-12
gi|89179321 smooth muscle cell associated protein-1 isoform 3 [H... 69 1e-11
gi|29725607 smooth muscle cell associated protein-1 isoform 2 [H... 69 1e-11
gi|5453980 DnaJ (Hsp40) homolog, subfamily C, member 3 [Homo sap... 67 4e-11
gi|75750484 cardiomyopathy associated 4 isoform 2 [Homo sapiens] 65 2e-10
gi|27477061 cardiomyopathy associated 4 isoform 1 [Homo sapiens] 65 2e-10
gi|75677570 dyslexia susceptibility 1 candidate 1 isoform a [Hom... 62 2e-09
gi|17149853 WAF-1/CIP1 stabilizing protein 39 [Homo sapiens] 62 2e-09
gi|56181387 STIP1 homology and U-box containing protein 1 [Homo ... 59 1e-08
gi|239756104 PREDICTED: tetratricopeptide repeat domain 6 [Homo ... 59 1e-08
gi|239750633 PREDICTED: tetratricopeptide repeat domain 6 [Homo ... 59 1e-08
>gi|225735593 RNA polymerase II associated protein 3 isoform 2 [Homo
sapiens]
Length = 631
Score = 1238 bits (3204), Expect = 0.0
Identities = 631/631 (100%), Positives = 631/631 (100%)
Query: 1 MTSANKAIELQLQVKQNAEELQDFMRDLENWEKDIKQKDMELRRQNGVPEENLPPIRNGN 60
MTSANKAIELQLQVKQNAEELQDFMRDLENWEKDIKQKDMELRRQNGVPEENLPPIRNGN
Sbjct: 1 MTSANKAIELQLQVKQNAEELQDFMRDLENWEKDIKQKDMELRRQNGVPEENLPPIRNGN 60
Query: 61 FRKKKKGKAKESSKKTREENTKNRIKSYDYEAWAKLDVDRILDELDKDDSTHESLSQESE 120
FRKKKKGKAKESSKKTREENTKNRIKSYDYEAWAKLDVDRILDELDKDDSTHESLSQESE
Sbjct: 61 FRKKKKGKAKESSKKTREENTKNRIKSYDYEAWAKLDVDRILDELDKDDSTHESLSQESE 120
Query: 121 SEEDGIHVDSQKALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRL 180
SEEDGIHVDSQKALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRL
Sbjct: 121 SEEDGIHVDSQKALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRL 180
Query: 181 KKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNFEATNE 240
KKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNFEATNE
Sbjct: 181 KKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNFEATNE 240
Query: 241 LRKISQALASKENSYPKEADIVIKSTEGERKQIEAQQNKQQAISEKDRGNGFFKEGKYER 300
LRKISQALASKENSYPKEADIVIKSTEGERKQIEAQQNKQQAISEKDRGNGFFKEGKYER
Sbjct: 241 LRKISQALASKENSYPKEADIVIKSTEGERKQIEAQQNKQQAISEKDRGNGFFKEGKYER 300
Query: 301 AIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTAR 360
AIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTAR
Sbjct: 301 AIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTAR 360
Query: 361 TFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIKKKPLKKVIIEETGNLIQTIDVPDSTT 420
TFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIKKKPLKKVIIEETGNLIQTIDVPDSTT
Sbjct: 361 TFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIKKKPLKKVIIEETGNLIQTIDVPDSTT 420
Query: 421 AAAPENNPINLANVIAATGTTSKKNSSQDDLFPTSDTPRAKVLKIEEVSDTSSLQPQASL 480
AAAPENNPINLANVIAATGTTSKKNSSQDDLFPTSDTPRAKVLKIEEVSDTSSLQPQASL
Sbjct: 421 AAAPENNPINLANVIAATGTTSKKNSSQDDLFPTSDTPRAKVLKIEEVSDTSSLQPQASL 480
Query: 481 KQDVCQSYSEKMPIEIEQKPAQFATTVLPPIPANSFQLESDFRQLKSSPDMLYQYLKQIE 540
KQDVCQSYSEKMPIEIEQKPAQFATTVLPPIPANSFQLESDFRQLKSSPDMLYQYLKQIE
Sbjct: 481 KQDVCQSYSEKMPIEIEQKPAQFATTVLPPIPANSFQLESDFRQLKSSPDMLYQYLKQIE 540
Query: 541 PSLYPKLFQKNLDPDVFNQIVKILHDFYIEKEKPLLIFEILQRLSELKRFDMAVMFMSET 600
PSLYPKLFQKNLDPDVFNQIVKILHDFYIEKEKPLLIFEILQRLSELKRFDMAVMFMSET
Sbjct: 541 PSLYPKLFQKNLDPDVFNQIVKILHDFYIEKEKPLLIFEILQRLSELKRFDMAVMFMSET 600
Query: 601 EKKIARALFNHIDKSGLKDSSVEELKKRYGG 631
EKKIARALFNHIDKSGLKDSSVEELKKRYGG
Sbjct: 601 EKKIARALFNHIDKSGLKDSSVEELKKRYGG 631
>gi|225735591 RNA polymerase II associated protein 3 isoform 1 [Homo
sapiens]
Length = 665
Score = 1221 bits (3159), Expect = 0.0
Identities = 631/665 (94%), Positives = 631/665 (94%), Gaps = 34/665 (5%)
Query: 1 MTSANKAIELQLQVKQNAEELQDFMRDLENWEKDIKQKDMELRRQNGVPEENLPPIRNGN 60
MTSANKAIELQLQVKQNAEELQDFMRDLENWEKDIKQKDMELRRQNGVPEENLPPIRNGN
Sbjct: 1 MTSANKAIELQLQVKQNAEELQDFMRDLENWEKDIKQKDMELRRQNGVPEENLPPIRNGN 60
Query: 61 FRKKKKGKAKESSKKTREENTKNRIKSYDYEAWAKLDVDRILDELDKDDSTHESLSQESE 120
FRKKKKGKAKESSKKTREENTKNRIKSYDYEAWAKLDVDRILDELDKDDSTHESLSQESE
Sbjct: 61 FRKKKKGKAKESSKKTREENTKNRIKSYDYEAWAKLDVDRILDELDKDDSTHESLSQESE 120
Query: 121 SEEDGIHVDSQKALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRL 180
SEEDGIHVDSQKALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRL
Sbjct: 121 SEEDGIHVDSQKALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRL 180
Query: 181 KKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNFEATNE 240
KKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNFEATNE
Sbjct: 181 KKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNFEATNE 240
Query: 241 LRKISQALASKENSYPKEADIVIKSTEGERKQIEAQQNKQQAISEKDRGNGFFKEGKYER 300
LRKISQALASKENSYPKEADIVIKSTEGERKQIEAQQNKQQAISEKDRGNGFFKEGKYER
Sbjct: 241 LRKISQALASKENSYPKEADIVIKSTEGERKQIEAQQNKQQAISEKDRGNGFFKEGKYER 300
Query: 301 AIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTAR 360
AIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTAR
Sbjct: 301 AIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTAR 360
Query: 361 TFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIKK------------------------- 395
TFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIKK
Sbjct: 361 TFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIKKELIEKGHWDDVFLDSTQRQNVVKPI 420
Query: 396 ---------KPLKKVIIEETGNLIQTIDVPDSTTAAAPENNPINLANVIAATGTTSKKNS 446
KPLKKVIIEETGNLIQTIDVPDSTTAAAPENNPINLANVIAATGTTSKKNS
Sbjct: 421 DNPPHPGSTKPLKKVIIEETGNLIQTIDVPDSTTAAAPENNPINLANVIAATGTTSKKNS 480
Query: 447 SQDDLFPTSDTPRAKVLKIEEVSDTSSLQPQASLKQDVCQSYSEKMPIEIEQKPAQFATT 506
SQDDLFPTSDTPRAKVLKIEEVSDTSSLQPQASLKQDVCQSYSEKMPIEIEQKPAQFATT
Sbjct: 481 SQDDLFPTSDTPRAKVLKIEEVSDTSSLQPQASLKQDVCQSYSEKMPIEIEQKPAQFATT 540
Query: 507 VLPPIPANSFQLESDFRQLKSSPDMLYQYLKQIEPSLYPKLFQKNLDPDVFNQIVKILHD 566
VLPPIPANSFQLESDFRQLKSSPDMLYQYLKQIEPSLYPKLFQKNLDPDVFNQIVKILHD
Sbjct: 541 VLPPIPANSFQLESDFRQLKSSPDMLYQYLKQIEPSLYPKLFQKNLDPDVFNQIVKILHD 600
Query: 567 FYIEKEKPLLIFEILQRLSELKRFDMAVMFMSETEKKIARALFNHIDKSGLKDSSVEELK 626
FYIEKEKPLLIFEILQRLSELKRFDMAVMFMSETEKKIARALFNHIDKSGLKDSSVEELK
Sbjct: 601 FYIEKEKPLLIFEILQRLSELKRFDMAVMFMSETEKKIARALFNHIDKSGLKDSSVEELK 660
Query: 627 KRYGG 631
KRYGG
Sbjct: 661 KRYGG 665
>gi|225735595 RNA polymerase II associated protein 3 isoform 3 [Homo
sapiens]
Length = 506
Score = 903 bits (2333), Expect = 0.0
Identities = 472/506 (93%), Positives = 472/506 (93%), Gaps = 34/506 (6%)
Query: 160 MDADPYNPVLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEE 219
MDADPYNPVLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEE
Sbjct: 1 MDADPYNPVLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEE 60
Query: 220 AKKDYERVLELEPNNFEATNELRKISQALASKENSYPKEADIVIKSTEGERKQIEAQQNK 279
AKKDYERVLELEPNNFEATNELRKISQALASKENSYPKEADIVIKSTEGERKQIEAQQNK
Sbjct: 61 AKKDYERVLELEPNNFEATNELRKISQALASKENSYPKEADIVIKSTEGERKQIEAQQNK 120
Query: 280 QQAISEKDRGNGFFKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDC 339
QQAISEKDRGNGFFKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDC
Sbjct: 121 QQAISEKDRGNGFFKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDC 180
Query: 340 TQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIKK---- 395
TQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIKK
Sbjct: 181 TQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIKKELIE 240
Query: 396 ------------------------------KPLKKVIIEETGNLIQTIDVPDSTTAAAPE 425
KPLKKVIIEETGNLIQTIDVPDSTTAAAPE
Sbjct: 241 KGHWDDVFLDSTQRQNVVKPIDNPPHPGSTKPLKKVIIEETGNLIQTIDVPDSTTAAAPE 300
Query: 426 NNPINLANVIAATGTTSKKNSSQDDLFPTSDTPRAKVLKIEEVSDTSSLQPQASLKQDVC 485
NNPINLANVIAATGTTSKKNSSQDDLFPTSDTPRAKVLKIEEVSDTSSLQPQASLKQDVC
Sbjct: 301 NNPINLANVIAATGTTSKKNSSQDDLFPTSDTPRAKVLKIEEVSDTSSLQPQASLKQDVC 360
Query: 486 QSYSEKMPIEIEQKPAQFATTVLPPIPANSFQLESDFRQLKSSPDMLYQYLKQIEPSLYP 545
QSYSEKMPIEIEQKPAQFATTVLPPIPANSFQLESDFRQLKSSPDMLYQYLKQIEPSLYP
Sbjct: 361 QSYSEKMPIEIEQKPAQFATTVLPPIPANSFQLESDFRQLKSSPDMLYQYLKQIEPSLYP 420
Query: 546 KLFQKNLDPDVFNQIVKILHDFYIEKEKPLLIFEILQRLSELKRFDMAVMFMSETEKKIA 605
KLFQKNLDPDVFNQIVKILHDFYIEKEKPLLIFEILQRLSELKRFDMAVMFMSETEKKIA
Sbjct: 421 KLFQKNLDPDVFNQIVKILHDFYIEKEKPLLIFEILQRLSELKRFDMAVMFMSETEKKIA 480
Query: 606 RALFNHIDKSGLKDSSVEELKKRYGG 631
RALFNHIDKSGLKDSSVEELKKRYGG
Sbjct: 481 RALFNHIDKSGLKDSSVEELKKRYGG 506
Score = 134 bits (337), Expect = 3e-31
Identities = 66/136 (48%), Positives = 93/136 (68%)
Query: 116 SQESESEEDGIHVDSQKALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRAS 175
S E E ++ + Q+A+ K++GN +FK+GKY+ AI+CYT+G+ AD N +LP NRA
Sbjct: 106 STEGERKQIEAQQNKQQAISEKDRGNGFFKEGKYERAIECYTRGIAADGANALLPANRAM 165
Query: 176 AYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNF 235
AY +++K+ AE DC A+ L+ SY+KA++RRG AR L KL EAK+D+E VL LEP N
Sbjct: 166 AYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLEPGNK 225
Query: 236 EATNELRKISQALASK 251
+A EL KI + L K
Sbjct: 226 QAVTELSKIKKELIEK 241
>gi|27262638 sperm associated antigen 1 [Homo sapiens]
Length = 926
Score = 114 bits (284), Expect = 4e-25
Identities = 133/607 (21%), Positives = 245/607 (40%), Gaps = 93/607 (15%)
Query: 55 PIRNGNFRKKKKGKAKESSKKTREENTKNRIKSYDYEAWAKLDVDRILDELDKDDSTHES 114
P GN +KK GKA+ + R + + EA A D+ ++ +
Sbjct: 379 PCVMGNIQKKLTGKAEGGKRPARGAPQRGQTP----EAGA--------DKRSPRRASAAA 426
Query: 115 LSQESESEEDGIHVDSQKALVLKEKGNKYFKQGKYDEAIDCYTK--------GMDADPYN 166
+ + G ++ LK +GN+ F+ G++ EA Y+ G +
Sbjct: 427 AAGGGATGHPGGGQGAENPAGLKSQGNELFRSGQFAEAAGKYSAAIALLEPAGSEIADDL 486
Query: 167 PVLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYER 226
+L +NRA+ Y + + DCN A+ L+ K RR A L++ +A DY+
Sbjct: 487 SILYSNRAACYLKEGNCSGCIQDCNRALELHPFSMKPLLRRAMAYETLEQYGKAYVDYKT 546
Query: 227 VLELEPNNFEATNELRKISQALASKENSYPKE---------ADIVIKSTEGERKQIEAQ- 276
VL+++ A + + ++S+ L + +E A + +++ ++ I Q
Sbjct: 547 VLQIDCGLQLANDSVNRLSRILMELDGPNWREKLSPIPAVPASVPLQAWHPAKEMISKQA 606
Query: 277 ----QNKQQAISE-------KDRGNGFFKEGKYERAIECYTRGIAADGANALLPANRAMA 325
++QQ I++ K+ GN + Y+ A+ Y+ + + + NRA+
Sbjct: 607 GDSSSHRQQGITDEKTFKALKEEGNQCVNDKNYKDALSKYSECLKINNKECAIYTNRALC 666
Query: 326 YLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLEPGNKQ 385
YLK+ ++EEA++DC QA+ L KAF RR A L ++ D V+LL+P +
Sbjct: 667 YLKLCQFEEAKQDCDQALQLADGNVKAFYRRALAHKGLKNYQKSLIDLNKVILLDPSIIE 726
Query: 386 AVTELSKIKKKPLKKVIIEETGNLIQTIDVPDSTTAAAPENNPINLANVIAATGTTSKKN 445
A EL ++ + +++ D T AP N + K+
Sbjct: 727 AKMELEEVTR----------------LLNLKDKT---APFNKEKERRKIEIQEVNEGKEE 767
Query: 446 SSQDDLFPTSDTPRAKVLKIEEVSDTSSLQPQASLKQDVCQSYSEKMPIEIEQKPAQFAT 505
+ P + + E SS P+ EK+PI +F
Sbjct: 768 PGR----PAGEVSMGCL--ASEKGGKSSRSPED----------PEKLPIAKPNNAYEFGQ 811
Query: 506 TVLPPIPANSFQLESDFRQLKSSPDMLYQYLKQIEPSLYPKLFQKNLDPDVFNQIVKILH 565
+ N+ D + L P P L+ D F +++ L
Sbjct: 812 II------NALSTRKD-------KEACAHLLAITAPKDLPMFLSNKLEGDTFLLLIQSLK 858
Query: 566 DFYIEKEKPLLIFEILQRLSELKRFDMAVMFMSETEKKIARALFNHIDKSGLKDSSVEE- 624
+ IEK+ P L+++ L LS+ +RF M + +S+ +K++ LF + + ++E+
Sbjct: 859 NNLIEKD-PSLVYQHLLYLSKAERFKMMLTLISKGQKELIEQLFEDLSDTPNNHFTLEDI 917
Query: 625 --LKKRY 629
LK++Y
Sbjct: 918 QALKRQY 924
Score = 102 bits (255), Expect = 8e-22
Identities = 82/284 (28%), Positives = 134/284 (47%), Gaps = 29/284 (10%)
Query: 18 AEELQDFMRDLENWEKDIKQKD--MELRRQNGVP--EENLPPIRNGNFRKKKKGKAKESS 73
AEE + D+++W +IK+++ M P ++NLPP+R N GK K S
Sbjct: 89 AEEWEKIDGDIKSWVSEIKKEEDKMHFHETETFPAMKDNLPPVRGSN-SCLHVGKEKYSK 147
Query: 74 KKTREENTKNRIKSYDYEAWAKLDVDRILDELDKD-------DSTHESLSQESESEEDGI 126
+ T+++ + DY W K DV++ ++D+D D +H S E+ + G+
Sbjct: 148 RPTKKKTPR------DYAEWDKFDVEKECLKIDEDYKEKTVIDKSHLS-KIETRIDTAGL 200
Query: 127 HVDSQKALVL--KEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRLKKFA 184
+ L KEKGN+ F G Y+EA+ YT+ + A P V NRA A +L+ +
Sbjct: 201 TEKEKDFLATREKEKGNEAFNSGDYEEAVMYYTRSISALP-TVVAYNNRAQAEIKLQNWN 259
Query: 185 VAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNFEATNELRKI 244
A DC + L KA RR KL EA +D +VL++EP+N A L ++
Sbjct: 260 SAFQDCEKVLELEPGNVKALLRRATTYKHQNKLREATEDLSKVLDVEPDNDLAKKTLSEV 319
Query: 245 SQALASKENSYPKEADIVIKSTEGERKQIEAQQNKQQAISEKDR 288
+ L + E + + T+G+R I+ +N + + R
Sbjct: 320 ERDLKNSEAASETQ-------TKGKRMVIQEIENSEDEEGKSGR 356
Score = 74.3 bits (181), Expect = 3e-13
Identities = 51/165 (30%), Positives = 80/165 (48%), Gaps = 3/165 (1%)
Query: 231 EPNNFEATNELRKISQALASKENSYPKEADIVIKSTEGERKQIEAQQNKQQAISEKDRGN 290
E + F+ E KI + KE + ++ + T + + ++ A EK++GN
Sbjct: 160 EWDKFDVEKECLKIDEDY--KEKTVIDKSHLSKIETRIDTAGLTEKEKDFLATREKEKGN 217
Query: 291 GFFKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAILLDGSYS 350
F G YE A+ YTR I+A + NRA A +K+Q + A +DC + + L+
Sbjct: 218 EAFNSGDYEEAVMYYTRSISAL-PTVVAYNNRAQAEIKLQNWNSAFQDCEKVLELEPGNV 276
Query: 351 KAFARRGTARTFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIKK 395
KA RR T KL EA +D VL +EP N A LS++++
Sbjct: 277 KALLRRATTYKHQNKLREATEDLSKVLDVEPDNDLAKKTLSEVER 321
>gi|27262636 sperm associated antigen 1 [Homo sapiens]
Length = 926
Score = 114 bits (284), Expect = 4e-25
Identities = 133/607 (21%), Positives = 245/607 (40%), Gaps = 93/607 (15%)
Query: 55 PIRNGNFRKKKKGKAKESSKKTREENTKNRIKSYDYEAWAKLDVDRILDELDKDDSTHES 114
P GN +KK GKA+ + R + + EA A D+ ++ +
Sbjct: 379 PCVMGNIQKKLTGKAEGGKRPARGAPQRGQTP----EAGA--------DKRSPRRASAAA 426
Query: 115 LSQESESEEDGIHVDSQKALVLKEKGNKYFKQGKYDEAIDCYTK--------GMDADPYN 166
+ + G ++ LK +GN+ F+ G++ EA Y+ G +
Sbjct: 427 AAGGGATGHPGGGQGAENPAGLKSQGNELFRSGQFAEAAGKYSAAIALLEPAGSEIADDL 486
Query: 167 PVLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYER 226
+L +NRA+ Y + + DCN A+ L+ K RR A L++ +A DY+
Sbjct: 487 SILYSNRAACYLKEGNCSGCIQDCNRALELHPFSMKPLLRRAMAYETLEQYGKAYVDYKT 546
Query: 227 VLELEPNNFEATNELRKISQALASKENSYPKE---------ADIVIKSTEGERKQIEAQ- 276
VL+++ A + + ++S+ L + +E A + +++ ++ I Q
Sbjct: 547 VLQIDCGLQLANDSVNRLSRILMELDGPNWREKLSPIPAVPASVPLQAWHPAKEMISKQA 606
Query: 277 ----QNKQQAISE-------KDRGNGFFKEGKYERAIECYTRGIAADGANALLPANRAMA 325
++QQ I++ K+ GN + Y+ A+ Y+ + + + NRA+
Sbjct: 607 GDSSSHRQQGITDEKTFKALKEEGNQCVNDKNYKDALSKYSECLKINNKECAIYTNRALC 666
Query: 326 YLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLEPGNKQ 385
YLK+ ++EEA++DC QA+ L KAF RR A L ++ D V+LL+P +
Sbjct: 667 YLKLCQFEEAKQDCDQALQLADGNVKAFYRRALAHKGLKNYQKSLIDLNKVILLDPSIIE 726
Query: 386 AVTELSKIKKKPLKKVIIEETGNLIQTIDVPDSTTAAAPENNPINLANVIAATGTTSKKN 445
A EL ++ + +++ D T AP N + K+
Sbjct: 727 AKMELEEVTR----------------LLNLKDKT---APFNKEKERRKIEIQEVNEGKEE 767
Query: 446 SSQDDLFPTSDTPRAKVLKIEEVSDTSSLQPQASLKQDVCQSYSEKMPIEIEQKPAQFAT 505
+ P + + E SS P+ EK+PI +F
Sbjct: 768 PGR----PAGEVSMGCL--ASEKGGKSSRSPED----------PEKLPIAKPNNAYEFGQ 811
Query: 506 TVLPPIPANSFQLESDFRQLKSSPDMLYQYLKQIEPSLYPKLFQKNLDPDVFNQIVKILH 565
+ N+ D + L P P L+ D F +++ L
Sbjct: 812 II------NALSTRKD-------KEACAHLLAITAPKDLPMFLSNKLEGDTFLLLIQSLK 858
Query: 566 DFYIEKEKPLLIFEILQRLSELKRFDMAVMFMSETEKKIARALFNHIDKSGLKDSSVEE- 624
+ IEK+ P L+++ L LS+ +RF M + +S+ +K++ LF + + ++E+
Sbjct: 859 NNLIEKD-PSLVYQHLLYLSKAERFKMMLTLISKGQKELIEQLFEDLSDTPNNHFTLEDI 917
Query: 625 --LKKRY 629
LK++Y
Sbjct: 918 QALKRQY 924
Score = 102 bits (255), Expect = 8e-22
Identities = 82/284 (28%), Positives = 134/284 (47%), Gaps = 29/284 (10%)
Query: 18 AEELQDFMRDLENWEKDIKQKD--MELRRQNGVP--EENLPPIRNGNFRKKKKGKAKESS 73
AEE + D+++W +IK+++ M P ++NLPP+R N GK K S
Sbjct: 89 AEEWEKIDGDIKSWVSEIKKEEDKMHFHETETFPAMKDNLPPVRGSN-SCLHVGKEKYSK 147
Query: 74 KKTREENTKNRIKSYDYEAWAKLDVDRILDELDKD-------DSTHESLSQESESEEDGI 126
+ T+++ + DY W K DV++ ++D+D D +H S E+ + G+
Sbjct: 148 RPTKKKTPR------DYAEWDKFDVEKECLKIDEDYKEKTVIDKSHLS-KIETRIDTAGL 200
Query: 127 HVDSQKALVL--KEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRLKKFA 184
+ L KEKGN+ F G Y+EA+ YT+ + A P V NRA A +L+ +
Sbjct: 201 TEKEKDFLATREKEKGNEAFNSGDYEEAVMYYTRSISALP-TVVAYNNRAQAEIKLQNWN 259
Query: 185 VAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNFEATNELRKI 244
A DC + L KA RR KL EA +D +VL++EP+N A L ++
Sbjct: 260 SAFQDCEKVLELEPGNVKALLRRATTYKHQNKLREATEDLSKVLDVEPDNDLAKKTLSEV 319
Query: 245 SQALASKENSYPKEADIVIKSTEGERKQIEAQQNKQQAISEKDR 288
+ L + E + + T+G+R I+ +N + + R
Sbjct: 320 ERDLKNSEAASETQ-------TKGKRMVIQEIENSEDEEGKSGR 356
Score = 74.3 bits (181), Expect = 3e-13
Identities = 51/165 (30%), Positives = 80/165 (48%), Gaps = 3/165 (1%)
Query: 231 EPNNFEATNELRKISQALASKENSYPKEADIVIKSTEGERKQIEAQQNKQQAISEKDRGN 290
E + F+ E KI + KE + ++ + T + + ++ A EK++GN
Sbjct: 160 EWDKFDVEKECLKIDEDY--KEKTVIDKSHLSKIETRIDTAGLTEKEKDFLATREKEKGN 217
Query: 291 GFFKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAILLDGSYS 350
F G YE A+ YTR I+A + NRA A +K+Q + A +DC + + L+
Sbjct: 218 EAFNSGDYEEAVMYYTRSISAL-PTVVAYNNRAQAEIKLQNWNSAFQDCEKVLELEPGNV 276
Query: 351 KAFARRGTARTFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIKK 395
KA RR T KL EA +D VL +EP N A LS++++
Sbjct: 277 KALLRRATTYKHQNKLREATEDLSKVLDVEPDNDLAKKTLSEVER 321
>gi|21361356 translocase of outer mitochondrial membrane 34 [Homo
sapiens]
Length = 309
Score = 113 bits (282), Expect = 6e-25
Identities = 84/295 (28%), Positives = 136/295 (46%), Gaps = 35/295 (11%)
Query: 136 LKEKGNKYFKQGKYDEAIDCYTKGM-------DADPYNP-VLPTNRASAYFRLKKFAVAE 187
L+ GN+ F+ G+Y EA Y + + +DP VL +NRA+ + +
Sbjct: 12 LRAAGNESFRNGQYAEASALYGRALRVLQAQGSSDPEEESVLYSNRAACHLKDGNCRDCI 71
Query: 188 SDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNFEATNELRKISQA 247
DC A+AL K RR +A AL+K A DY+ VL+++ N A + ++++A
Sbjct: 72 KDCTSALALVPFSIKPLLRRASAYEALEKYPMAYVDYKTVLQIDDNVTSAVEGINRMTRA 131
Query: 248 LAS----------------------KENSYPKE-----ADIVIKSTEGERKQIEAQQNKQ 280
L + NS P E A K T + ++ + + +
Sbjct: 132 LMDSLGPEWRLKLPSIPLVPVSAQKRWNSLPSENHKEMAKSKSKETTATKNRVPSAGDVE 191
Query: 281 QAISEKDRGNGFFKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCT 340
+A K+ GN K+G +++AIE Y+ + + +NRA+ YL +++Y EA KDCT
Sbjct: 192 KARVLKEEGNELVKKGNHKKAIEKYSESLLCSNLESATYSNRALCYLVLKQYTEAVKDCT 251
Query: 341 QAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIKK 395
+A+ LDG KAF RR A L + D +L +EP N A ++K+
Sbjct: 252 EALKLDGKNVKAFYRRAQAHKALKDYKSSFADISNLLQIEPRNGPAQKLRQEVKQ 306
Score = 71.6 bits (174), Expect = 2e-12
Identities = 40/120 (33%), Positives = 65/120 (54%)
Query: 129 DSQKALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRLKKFAVAES 188
D +KA VLKE+GN+ K+G + +AI+ Y++ + +NRA Y LK++ A
Sbjct: 189 DVEKARVLKEEGNELVKKGNHKKAIEKYSESLLCSNLESATYSNRALCYLVLKQYTEAVK 248
Query: 189 DCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNFEATNELRKISQAL 248
DC A+ L+ KA+ RR A AL+ + + D +L++EP N A +++ Q L
Sbjct: 249 DCTEALKLDGKNVKAFYRRAQAHKALKDYKSSFADISNLLQIEPRNGPAQKLRQEVKQNL 308
>gi|5803181 stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizing
protein) [Homo sapiens]
Length = 543
Score = 103 bits (256), Expect = 6e-22
Identities = 77/274 (28%), Positives = 130/274 (47%), Gaps = 28/274 (10%)
Query: 120 ESEEDGIHVDSQKALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFR 179
E E+ + + ++AL KE GN +K+ +D A+ Y K + DP N TN+A+ YF
Sbjct: 212 EPMEEDLPENKKQALKEKELGNDAYKKKDFDTALKHYDKAKELDPTNMTYITNQAAVYFE 271
Query: 180 LKKFAVAESDCNLAVALN-------RSYTKAYSRRGAARFALQKLEEAKKDYERVLELEP 232
+ C A+ + R KAY+R G + F +K ++A Y + L
Sbjct: 272 KGDYNKCRELCEKAIEVGRENREDYRQIAKAYARIGNSYFKEEKYKDAIHFYNKSLA--- 328
Query: 233 NNFEATNELRKISQALASKENSYPKEADIVIKSTEGERKQIEAQQNKQQAISEKDRGNGF 292
+ L+K Q A+ ++K E ER A N A+ EK++GN
Sbjct: 329 -EHRTPDVLKKCQQ------------AEKILK--EQERL---AYINPDLALEEKNKGNEC 370
Query: 293 FKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAILLDGSYSKA 352
F++G Y +A++ YT I + +A L +NRA Y K+ +++ A KDC + I L+ ++ K
Sbjct: 371 FQKGDYPQAMKHYTEAIKRNPKDAKLYSNRAACYTKLLEFQLALKDCEECIQLEPTFIKG 430
Query: 353 FARRGTARTFLGKLNEAKQDFETVLLLEPGNKQA 386
+ R+ A + +A ++ L L+ K+A
Sbjct: 431 YTRKAAALEAMKDYTKAMDVYQKALDLDSSCKEA 464
Score = 83.2 bits (204), Expect = 7e-16
Identities = 57/163 (34%), Positives = 83/163 (50%), Gaps = 12/163 (7%)
Query: 136 LKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRLKKFAVAESDCNLAVA 195
LKEKGNK G D+A+ CY++ + DP+N VL +NR++AY + + A D V
Sbjct: 7 LKEKGNKALSVGNIDDALQCYSEAIKLDPHNHVLYSNRSAAYAKKGDYQKAYEDGCKTVD 66
Query: 196 LNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNFEATNELRKISQALASKE--- 252
L + K YSR+ AA L + EEAK+ YE L+ E NN + L+ + LA ++
Sbjct: 67 LKPDWGKGYSRKAAALEFLNRFEEAKRTYEEGLKHEANNPQLKEGLQNMEARLAERKFMN 126
Query: 253 -----NSYPK-EAD---IVIKSTEGERKQIEAQQNKQQAISEK 286
N Y K E+D + S R+ IE +NK + K
Sbjct: 127 PFNMPNLYQKLESDPRTRTLLSDPTYRELIEQLRNKPSDLGTK 169
Score = 82.4 bits (202), Expect = 1e-15
Identities = 68/262 (25%), Positives = 128/262 (48%), Gaps = 29/262 (11%)
Query: 33 KDIKQKDMELRRQNGVPEENLPPIRNGNFRKKKKGKAKESSKKTREENTKNRIKSYDYEA 92
+++ +K +E+ R+N ++R+ K A+ + +EE K+ I Y+
Sbjct: 279 RELCEKAIEVGREN-----------REDYRQIAKAYARIGNSYFKEEKYKDAIHFYN--- 324
Query: 93 WAKLDVDRILDELDKDDSTHESLSQESESEEDGIHVDSQKALVLKEKGNKYFKQGKYDEA 152
L R D L K + L ++ E +++ AL K KGN+ F++G Y +A
Sbjct: 325 -KSLAEHRTPDVLKKCQQAEKILKEQ----ERLAYINPDLALEEKNKGNECFQKGDYPQA 379
Query: 153 IDCYTKGMDADPYNPVLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARF 212
+ YT+ + +P + L +NRA+ Y +L +F +A DC + L ++ K Y+R+ AA
Sbjct: 380 MKHYTEAIKRNPKDAKLYSNRAACYTKLLEFQLALKDCEECIQLEPTFIKGYTRKAAALE 439
Query: 213 ALQKLEEAKKDYERVLELEPNNFEATNELRKISQALASKENSYPKE------ADIVIK-- 264
A++ +A Y++ L+L+ + EA + ++ A ++ +S P++ AD ++
Sbjct: 440 AMKDYTKAMDVYQKALDLDSSCKEAADGYQRCMMAQYNRHDS-PEDVKRRAMADPEVQQI 498
Query: 265 -STEGERKQIEAQQNKQQAISE 285
S R +E Q QA+SE
Sbjct: 499 MSDPAMRLILEQMQKDPQALSE 520
Score = 64.7 bits (156), Expect = 2e-10
Identities = 35/117 (29%), Positives = 60/117 (51%)
Query: 280 QQAISEKDRGNGFFKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDC 339
+Q K++GN G + A++CY+ I D N +L +NR+ AY K Y++A +D
Sbjct: 2 EQVNELKEKGNKALSVGNIDDALQCYSEAIKLDPHNHVLYSNRSAAYAKKGDYQKAYEDG 61
Query: 340 TQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIKKK 396
+ + L + K ++R+ A FL + EAK+ +E L E N Q L ++ +
Sbjct: 62 CKTVDLKPDWGKGYSRKAAALEFLNRFEEAKRTYEEGLKHEANNPQLKEGLQNMEAR 118
Score = 50.4 bits (119), Expect = 5e-06
Identities = 64/283 (22%), Positives = 109/283 (38%), Gaps = 49/283 (17%)
Query: 124 DGIHVDSQKALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRLKKF 183
+ I +D ++ + Y K+G Y +A + K +D P + +A+A L +F
Sbjct: 29 EAIKLDPHNHVLYSNRSAAYAKKGDYQKAYEDGCKTVDLKPDWGKGYSRKAAALEFLNRF 88
Query: 184 AVAES--DCNLAVALNRSYTKAYSRRGAARFA-------------LQKLEEAKKDYERVL 228
A+ + L N K + AR A QKLE + R L
Sbjct: 89 EEAKRTYEEGLKHEANNPQLKEGLQNMEARLAERKFMNPFNMPNLYQKLESDPRT--RTL 146
Query: 229 ELEPNNFEATNELRKISQALASKEN-----------------SYPKEADIVI-------- 263
+P E +LR L +K S +E +I
Sbjct: 147 LSDPTYRELIEQLRNKPSDLGTKLQDPRIMTTLSVLLGVDLGSMDEEEEIATPPPPPPPK 206
Query: 264 KSTEGERKQIEAQQNKQQAISEKDRGNGFFKEGKYERAIECYTRGIAADGANALLPANRA 323
K T+ E + + +NK+QA+ EK+ GN +K+ ++ A++ Y + D N N+A
Sbjct: 207 KETKPEPMEEDLPENKKQALKEKELGNDAYKKKDFDTALKHYDKAKELDPTNMTYITNQA 266
Query: 324 MAYLKIQKYEEAEKDCTQAILLD-------GSYSKAFARRGTA 359
Y + Y + + C +AI + +KA+AR G +
Sbjct: 267 AVYFEKGDYNKCRELCEKAIEVGRENREDYRQIAKAYARIGNS 309
>gi|24308141 small glutamine-rich tetratricopeptide repeat
(TPR)-containing, beta [Homo sapiens]
Length = 304
Score = 95.9 bits (237), Expect = 1e-19
Identities = 49/120 (40%), Positives = 70/120 (58%)
Query: 129 DSQKALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRLKKFAVAES 188
D KA LK++GN + K+ Y A+DCYT+ ++ DP N V NRA+A +L + A
Sbjct: 81 DVGKADQLKDEGNNHMKEENYAAAVDCYTQAIELDPNNAVYYCNRAAAQSKLGHYTDAIK 140
Query: 189 DCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNFEATNELRKISQAL 248
DC A+A++ Y+KAY R G A AL K EEA Y++ L+L+P N + L+ Q L
Sbjct: 141 DCEKAIAIDSKYSKAYGRMGLALTALNKFEEAVTSYQKALDLDPENDSYKSNLKIAEQKL 200
Score = 89.7 bits (221), Expect = 7e-18
Identities = 49/116 (42%), Positives = 66/116 (56%), Gaps = 1/116 (0%)
Query: 286 KDRGNGFFKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAILL 345
KD GN KE Y A++CYT+ I D NA+ NRA A K+ Y +A KDC +AI +
Sbjct: 89 KDEGNNHMKEENYAAAVDCYTQAIELDPNNAVYYCNRAAAQSKLGHYTDAIKDCEKAIAI 148
Query: 346 DGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIKKKPLKKV 401
D YSKA+ R G A T L K EA ++ L L+P N + L KI ++ L++V
Sbjct: 149 DSKYSKAYGRMGLALTALNKFEEAVTSYQKALDLDPENDSYKSNL-KIAEQKLREV 203
Score = 32.3 bits (72), Expect = 1.4
Identities = 30/117 (25%), Positives = 54/117 (46%), Gaps = 15/117 (12%)
Query: 78 EENTKNRIKSYDYEAWAKLDVDRILDELDKDDSTHESLSQESESE----EDGIHVDSQKA 133
++ N +K +Y A I ELD +++ + ++S+ D I D +KA
Sbjct: 89 KDEGNNHMKEENYAAAVDCYTQAI--ELDPNNAVYYCNRAAAQSKLGHYTDAIK-DCEKA 145
Query: 134 LVLKEKGNK-YFKQG-------KYDEAIDCYTKGMDADPYNPVLPTNRASAYFRLKK 182
+ + K +K Y + G K++EA+ Y K +D DP N +N A +L++
Sbjct: 146 IAIDSKYSKAYGRMGLALTALNKFEEAVTSYQKALDLDPENDSYKSNLKIAEQKLRE 202
>gi|54607135 translocase of outer mitochondrial membrane 70 homolog
A [Homo sapiens]
Length = 608
Score = 93.2 bits (230), Expect = 6e-19
Identities = 83/281 (29%), Positives = 121/281 (43%), Gaps = 37/281 (13%)
Query: 122 EEDGIHVDSQ---KALVLKEKGNKYFKQGKYDEAIDCYTKGMDADP--YNPVLPT---NR 173
E G H+D +A K KGNKYFK GKY++AI CYT+ + P N L T NR
Sbjct: 100 EGPGAHLDMNSLDRAQAAKNKGNKYFKAGKYEQAIQCYTEAISLCPTEKNVDLSTFYQNR 159
Query: 174 ASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPN 233
A+A+ +L+K+ DC AV LN Y KA RR A L +E +D V LE
Sbjct: 160 AAAFEQLQKWKEVAQDCTKAVELNPKYVKALFRRAKAHEKLDNKKECLEDVTAVCILE-- 217
Query: 234 NFEATNELRKISQALASKENSYPKEADIVIKSTEGERKQIEAQQNKQQAISEKDRGNGFF 293
F+ + S LA K + G+ K E +N++ + +F
Sbjct: 218 GFQ-----NQQSMLLADK-----------VLKLLGKEKAKEKYKNREPLMPSPQFIKSYF 261
Query: 294 KEGKYERAIECYTRGIAA----DGANALLPANRAMAYLKIQKYEEAE------KDCTQAI 343
+ + +G + D L YLK ++Y E E +C++ I
Sbjct: 262 SSFTDDIISQPMLKGEKSDEDKDKEGEALEVKENSGYLKAKQYMEEENYDKIISECSKEI 321
Query: 344 LLDGSY-SKAFARRGTARTFLGKLNEAKQDFETVLLLEPGN 383
+G Y ++A R T +G N AK D + V+ L+ N
Sbjct: 322 DAEGKYMAEALLLRATFYLLIGNANAAKPDLDKVISLKEAN 362
Score = 75.1 bits (183), Expect = 2e-13
Identities = 44/121 (36%), Positives = 68/121 (56%), Gaps = 6/121 (4%)
Query: 281 QAISEKDRGNGFFKEGKYERAIECYTRGIAADGAN-----ALLPANRAMAYLKIQKYEEA 335
+A + K++GN +FK GKYE+AI+CYT I+ + NRA A+ ++QK++E
Sbjct: 113 RAQAAKNKGNKYFKAGKYEQAIQCYTEAISLCPTEKNVDLSTFYQNRAAAFEQLQKWKEV 172
Query: 336 EKDCTQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLEP-GNKQAVTELSKIK 394
+DCT+A+ L+ Y KA RR A L E +D V +LE N+Q++ K+
Sbjct: 173 AQDCTKAVELNPKYVKALFRRAKAHEKLDNKKECLEDVTAVCILEGFQNQQSMLLADKVL 232
Query: 395 K 395
K
Sbjct: 233 K 233
Score = 40.8 bits (94), Expect = 0.004
Identities = 56/286 (19%), Positives = 108/286 (37%), Gaps = 31/286 (10%)
Query: 108 DDSTHESLSQESESEEDGIHVDSQKALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNP 167
++ ++ + E E D +AL+L+ Y G + A K + N
Sbjct: 306 EEENYDKIISECSKEIDAEGKYMAEALLLR--ATFYLLIGNANAAKPDLDKVISLKEANV 363
Query: 168 VLPTN----RASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKD 223
L N R S Y + ++ ++ D N+A ++ Y RG + L ++EEA D
Sbjct: 364 KLRANALIKRGSMYMQQQQPLLSTQDFNMAADIDPQNADVYHHRGQLKILLDQVEEAVAD 423
Query: 224 YERVLELEPNNFEATNELRKISQALASKENSYPKEADIVIKSTEGERKQIEAQQNKQQAI 283
++ + L P + L + + A +Y T QI+A + +
Sbjct: 424 FDECIRLRPE-----SALAQAQKCFALYRQAY----------TGNNSSQIQAAMKGFEEV 468
Query: 284 SEK----DRGNGFFKEG-----KYERAIECYTRGIAADGANALLPANRAMAYLK-IQKYE 333
+K G + + ++ +A E Y + I + NA ++ + L+ Q +
Sbjct: 469 IKKFPRCAEGYALYAQALTDQQQFGKADEMYDKCIDLEPDNATTYVHKGLLQLQWKQDLD 528
Query: 334 EAEKDCTQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLLL 379
+ ++AI +D A+ GT G + +A F + L
Sbjct: 529 RGLELISKAIEIDNKCDFAYETMGTIEVQRGNMEKAIDMFNKAINL 574
>gi|221219053 DnaJ (Hsp40) homolog, subfamily C, member 7 isoform 1
[Homo sapiens]
Length = 494
Score = 87.4 bits (215), Expect = 4e-17
Identities = 89/361 (24%), Positives = 138/361 (38%), Gaps = 89/361 (24%)
Query: 131 QKALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRLKKFAVA---- 186
++A KE+GN Y+ + Y+EA + YTK +D P N NRA+ L +F A
Sbjct: 26 REAETFKEQGNAYYAKKDYNEAYNYYTKAIDMCPKNASYYGNRAATLMMLGRFREALGDA 85
Query: 187 ----------------ESDCNL----AVALNRSYTKAYSRRGAARFALQKLEEAKK--DY 224
E C+L A+A RS+ +A A Q+ + A +Y
Sbjct: 86 QQSVRLDDSFVRGHLREGKCHLSLGNAMAACRSFQRALELDHKNAQAQQEFKNANAVMEY 145
Query: 225 ERVLE--LEPNNFE--------------ATNELRKISQALASKENSYPKEADIV------ 262
E++ E E +F A + + + + YP+ +
Sbjct: 146 EKIAETDFEKRDFRKVVFCMDRALEFAPACHRFKILKAECLAMLGRYPEAQSVASDILRM 205
Query: 263 -------------------------------IKSTEGERKQIEAQQNKQQAISEKDRGNG 291
++ K A +N + ++K+ GN
Sbjct: 206 DSTNADALYVRGLCLYYEDCIEKAVQFFVQALRMAPDHEKACIACRNAKALKAKKEDGNK 265
Query: 292 FFKEGKYERAIECYTRGIAADG----ANALLPANRAMAYLKIQKYEEAEKDCTQAILLDG 347
FKEG Y+ A E YT + D NA L NR K++K ++A +DCT A+ LD
Sbjct: 266 AFKEGNYKLAYELYTEALGIDPNNIKTNAKLYCNRGTVNSKLRKLDDAIEDCTNAVKLDD 325
Query: 348 SYSKAFARRGTARTFLGKLNEAKQDFETVLLLEPGN------KQAVTELSKIKKKPLKKV 401
+Y KA+ RR + EA +D+E V E K A EL K K+K K+
Sbjct: 326 TYIKAYLRRAQCYMDTEQYEEAVRDYEKVYQTEKTKEHKQLLKNAQLELRKSKRKDYYKI 385
Query: 402 I 402
+
Sbjct: 386 L 386
Score = 75.9 bits (185), Expect = 1e-13
Identities = 64/198 (32%), Positives = 91/198 (45%), Gaps = 20/198 (10%)
Query: 113 ESLSQESESEEDGIHVDSQKAL-VLKEKGNKYFKQGKYDEAIDCYTKGMDADPYN----P 167
++L + E+ I + KAL KE GNK FK+G Y A + YT+ + DP N
Sbjct: 235 QALRMAPDHEKACIACRNAKALKAKKEDGNKAFKEGNYKLAYELYTEALGIDPNNIKTNA 294
Query: 168 VLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERV 227
L NR + +L+K A DC AV L+ +Y KAY RR ++ EEA +DYE+V
Sbjct: 295 KLYCNRGTVNSKLRKLDDAIEDCTNAVKLDDTYIKAYLRRAQCYMDTEQYEEAVRDYEKV 354
Query: 228 LELEPNN------FEATNELRKISQALASKENSYPKEADIVIKSTEGERKQIEAQQNKQQ 281
+ E A ELRK SK Y K + ++E E I+ K+
Sbjct: 355 YQTEKTKEHKQLLKNAQLELRK------SKRKDYYKILGVDKNASEDE---IKKAYRKRA 405
Query: 282 AISEKDRGNGFFKEGKYE 299
+ DR +G E + E
Sbjct: 406 LMHHPDRHSGASAEVQKE 423
Score = 68.2 bits (165), Expect = 2e-11
Identities = 41/132 (31%), Positives = 67/132 (50%), Gaps = 2/132 (1%)
Query: 258 EADIVIKSTEGERKQIEAQQNKQQAISEKDRGNGFFKEGKYERAIECYTRGIAADGANAL 317
E D+V+ +TE E ++ Q+ K++A + K++GN ++ + Y A YT+ I NA
Sbjct: 6 ECDVVMAATEPEL--LDDQEAKREAETFKEQGNAYYAKKDYNEAYNYYTKAIDMCPKNAS 63
Query: 318 LPANRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVL 377
NRA + + ++ EA D Q++ LD S+ + R G LG A + F+ L
Sbjct: 64 YYGNRAATLMMLGRFREALGDAQQSVRLDDSFVRGHLREGKCHLSLGNAMAACRSFQRAL 123
Query: 378 LLEPGNKQAVTE 389
L+ N QA E
Sbjct: 124 ELDHKNAQAQQE 135
>gi|5453958 protein phosphatase 5, catalytic subunit [Homo sapiens]
Length = 499
Score = 82.4 bits (202), Expect = 1e-15
Identities = 50/159 (31%), Positives = 86/159 (54%), Gaps = 6/159 (3%)
Query: 267 EGERKQIEAQQNKQQAISEKDRGNGFFKEGKYERAIECYTRGIAADGANALLPANRAMAY 326
E R + A ++A K + N +FK YE AI+ Y++ I + +NA+ NR++AY
Sbjct: 13 EPPRDEPPADGALKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAY 72
Query: 327 LKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLEPGNKQA 386
L+ + Y A D T+AI LD Y K + RR + LGK A +D+ETV+ ++P +K A
Sbjct: 73 LRTECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPHDKDA 132
Query: 387 VTELSK----IKKKPLKKVII--EETGNLIQTIDVPDST 419
+ + +K+K ++ I E +++ ++D+ T
Sbjct: 133 KMKYQECNKIVKQKAFERAIAGDEHKRSVVDSLDIESMT 171
Score = 78.6 bits (192), Expect = 2e-14
Identities = 39/121 (32%), Positives = 70/121 (57%)
Query: 131 QKALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRLKKFAVAESDC 190
++A LK + N YFK Y+ AI Y++ ++ +P N + NR+ AY R + + A D
Sbjct: 26 KRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDA 85
Query: 191 NLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNFEATNELRKISQALAS 250
A+ L++ Y K Y RR A+ AL K A +DYE V++++P++ +A + ++ ++ +
Sbjct: 86 TRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPHDKDAKMKYQECNKIVKQ 145
Query: 251 K 251
K
Sbjct: 146 K 146
>gi|4506921 small glutamine-rich tetratricopeptide [Homo sapiens]
Length = 313
Score = 80.9 bits (198), Expect = 3e-15
Identities = 48/141 (34%), Positives = 79/141 (56%), Gaps = 2/141 (1%)
Query: 96 LDVDRILDELDKDDSTHESLSQE--SESEEDGIHVDSQKALVLKEKGNKYFKQGKYDEAI 153
L + + L E+ + +T + + Q+ S + DS +A LK +GN+ K ++ A+
Sbjct: 52 LALPQTLPEIFEAAATGKEMPQDLRSPARTPPSEEDSAEAERLKTEGNEQMKVENFEAAV 111
Query: 154 DCYTKGMDADPYNPVLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFA 213
Y K ++ +P N V NRA+AY +L +A A DC A+ ++ +Y+KAY R G A +
Sbjct: 112 HFYGKAIELNPANAVYFCNRAAAYSKLGNYAGAVQDCERAICIDPAYSKAYGRMGLALSS 171
Query: 214 LQKLEEAKKDYERVLELEPNN 234
L K EA Y++ LEL+P+N
Sbjct: 172 LNKHVEAVAYYKKALELDPDN 192
Score = 76.3 bits (186), Expect = 8e-14
Identities = 58/168 (34%), Positives = 80/168 (47%), Gaps = 21/168 (12%)
Query: 232 PNNFEATNELRKISQALASKENSYPKEADIVIKSTEGERKQIEAQQNKQQAISEKDRGNG 291
P FEA +++ Q L S + P E D S E ER + E GN
Sbjct: 59 PEIFEAAATGKEMPQDLRSPARTPPSEED----SAEAERLKTE--------------GNE 100
Query: 292 FFKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAILLDGSYSK 351
K +E A+ Y + I + ANA+ NRA AY K+ Y A +DC +AI +D +YSK
Sbjct: 101 QMKVENFEAAVHFYGKAIELNPANAVYFCNRAAAYSKLGNYAGAVQDCERAICIDPAYSK 160
Query: 352 AFARRGTARTFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIKKKPLK 399
A+ R G A + L K EA ++ L L+P N+ T S +K LK
Sbjct: 161 AYGRMGLALSSLNKHVEAVAYYKKALELDPDNE---TYKSNLKIAELK 205
>gi|90669931 tetratricopeptide repeat domain 12 [Homo sapiens]
Length = 705
Score = 79.3 bits (194), Expect = 1e-14
Identities = 72/295 (24%), Positives = 143/295 (48%), Gaps = 34/295 (11%)
Query: 4 ANKAIELQLQVKQNAEELQDFMRDLENWEKDIKQKD-MELRRQNGVPEENLPPIRNGNFR 62
A+K +LQ +K N +E+ + ++++ + + ++QK +E ++ + EE+
Sbjct: 3 ADKEKDLQKFLK-NVDEISNLIQEMNSDDPVVQQKAVLETEKRLLLMEED---------- 51
Query: 63 KKKKGKAKESSKKTREENTKNRIKSYDYEAWAKLDVDRILDELDKDDSTHESLSQESESE 122
+++ + + + KT + +KS + +++ + L ++KD +E++
Sbjct: 52 -QEEDECRTTLNKTMISPPQTAMKSAE-----EINSEAFLASVEKDAKERAKRRRENKVL 105
Query: 123 EDGIHVDSQKALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRLKK 182
D LKEKGN+ F +G Y+ AI Y++G++ VL TNRA AY +L+
Sbjct: 106 ADA----------LKEKGNEAFAEGNYETAILRYSEGLEKLKDMKVLYTNRAQAYMKLED 155
Query: 183 FAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPN-NFEATNEL 241
+ A DC A+ + TKAY G A AL+ +++ Y+++LE+ P + L
Sbjct: 156 YEKALVDCEWALKCDEKCTKAYFHMGKANLALKNYSVSRECYKKILEINPKLQTQVKGYL 215
Query: 242 RKISQALASKENSYPKEADIVIKSTEGERKQIEAQQNKQQAISEKDRGNGFFKEG 296
++ L K + KEA ++ S G+ + +N + +S+ D+ F+ G
Sbjct: 216 NQVD--LQEKADLQEKEAHELLDS--GKNTAV-TTKNLLETLSKPDQIPLFYAGG 265
Score = 70.1 bits (170), Expect = 6e-12
Identities = 47/175 (26%), Positives = 86/175 (49%), Gaps = 15/175 (8%)
Query: 258 EADIVIKSTEGERKQIEAQQNKQQAISEKDRGNGFFKEGKYERAIECYTRGIAADGANAL 317
EA + + + + ++NK A + K++GN F EG YE AI Y+ G+ +
Sbjct: 82 EAFLASVEKDAKERAKRRRENKVLADALKEKGNEAFAEGNYETAILRYSEGLEKLKDMKV 141
Query: 318 LPANRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVL 377
L NRA AY+K++ YE+A DC A+ D +KA+ G A L + +++ ++ +L
Sbjct: 142 LYTNRAQAYMKLEDYEKALVDCEWALKCDEKCTKAYFHMGKANLALKNYSVSRECYKKIL 201
Query: 378 LLEPG---------NKQAVTELSKIKKKPLKKVI------IEETGNLIQTIDVPD 417
+ P N+ + E + +++K +++ T NL++T+ PD
Sbjct: 202 EINPKLQTQVKGYLNQVDLQEKADLQEKEAHELLDSGKNTAVTTKNLLETLSKPD 256
>gi|4507711 tetratricopeptide repeat domain 1 [Homo sapiens]
Length = 292
Score = 76.6 bits (187), Expect = 6e-14
Identities = 54/194 (27%), Positives = 94/194 (48%), Gaps = 18/194 (9%)
Query: 71 ESSKKTREENTKNRIKSYDYEAWAKLDVDR-ILDELDKDDSTHESLSQESESEEDGIHVD 129
+ S EE +++++ E ++D L EL+K+ S E + ES
Sbjct: 65 DCSASFEEEPGADKVENKSNEDVNSSELDEEYLIELEKNMSDEEKQKRREESTR------ 118
Query: 130 SQKALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPY-----NPVLPTNRASAYFRLKKFA 184
LKE+GN+ FK+G Y EA Y++ ++ P +L +NRA+A + K
Sbjct: 119 ------LKEEGNEQFKKGDYIEAESSYSRALEMCPSCFQKERSILFSNRAAARMKQDKKE 172
Query: 185 VAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNFEATNELRKI 244
+A +DC+ A+ LN SY +A RR KL+EA +DY+ +LE +P+ +A ++
Sbjct: 173 MAINDCSKAIQLNPSYIRAILRRAELYEKTDKLDEALEDYKSILEKDPSIHQAREACMRL 232
Query: 245 SQALASKENSYPKE 258
+ + + +E
Sbjct: 233 PKQIEERNERLKEE 246
Score = 67.0 bits (162), Expect = 5e-11
Identities = 48/168 (28%), Positives = 81/168 (48%), Gaps = 6/168 (3%)
Query: 234 NFEATNELRKISQALASKENSYPKEADIVIKSTEGERKQIEAQQNKQQAISEKDRGNGFF 293
+FE K+ NS + + +I+ E E Q+ ++++ K+ GN F
Sbjct: 69 SFEEEPGADKVENKSNEDVNSSELDEEYLIE-LEKNMSDEEKQKRREESTRLKEEGNEQF 127
Query: 294 KEGKYERAIECYTRGIAA-----DGANALLPANRAMAYLKIQKYEEAEKDCTQAILLDGS 348
K+G Y A Y+R + ++L +NRA A +K K E A DC++AI L+ S
Sbjct: 128 KKGDYIEAESSYSRALEMCPSCFQKERSILFSNRAAARMKQDKKEMAINDCSKAIQLNPS 187
Query: 349 YSKAFARRGTARTFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIKKK 396
Y +A RR KL+EA +D++++L +P QA ++ K+
Sbjct: 188 YIRAILRRAELYEKTDKLDEALEDYKSILEKDPSIHQAREACMRLPKQ 235
>gi|224809329 FK506 binding protein 5 isoform 1 [Homo sapiens]
Length = 457
Score = 76.3 bits (186), Expect = 8e-14
Identities = 50/154 (32%), Positives = 85/154 (55%), Gaps = 17/154 (11%)
Query: 260 DIVIKSTEGERK--QIEAQQNKQQAISEKDRGNGFFKEGKYERAIECYTR---------G 308
++ +KS E ++ +++ ++ +QA K++G +FK GKY +A+ Y + G
Sbjct: 244 EVTLKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYG 303
Query: 309 IAADGANA----LLPA--NRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTF 362
++ + A LL A N AM YLK+++Y +A + C +A+ LD + K RRG A+
Sbjct: 304 LSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLL 363
Query: 363 LGKLNEAKQDFETVLLLEPGNKQAVTELSKIKKK 396
+ + AK DFE VL + P NK A ++S +KK
Sbjct: 364 MNEFESAKGDFEKVLEVNPQNKAARLQISMCQKK 397
Score = 68.2 bits (165), Expect = 2e-11
Identities = 54/192 (28%), Positives = 91/192 (47%), Gaps = 19/192 (9%)
Query: 111 THESLSQESESEEDGIHVDSQKALVLKEKGNKYFKQGKYDEAIDCYTKGMD--------- 161
T +S + ES E ++A ++KEKG YFK GKY +A+ Y K +
Sbjct: 246 TLKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYGLS 305
Query: 162 ------ADPYNPVLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQ 215
++ + N A Y +L+++ A C+ A+ L+ + K RRG A+ +
Sbjct: 306 EKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMN 365
Query: 216 KLEEAKKDYERVLELEPNNFEATNELRKISQALASKENSYPKE--ADIVIKSTEGERKQI 273
+ E AK D+E+VLE+ P N A ++ + Q A + N + A++ K E + K+
Sbjct: 366 EFESAKGDFEKVLEVNPQNKAARLQI-SMCQKKAKEHNERDRRIYANMFKKFAEQDAKE- 423
Query: 274 EAQQNKQQAISE 285
EA + + SE
Sbjct: 424 EANKAMGKKTSE 435
>gi|224809327 FK506 binding protein 5 isoform 1 [Homo sapiens]
Length = 457
Score = 76.3 bits (186), Expect = 8e-14
Identities = 50/154 (32%), Positives = 85/154 (55%), Gaps = 17/154 (11%)
Query: 260 DIVIKSTEGERK--QIEAQQNKQQAISEKDRGNGFFKEGKYERAIECYTR---------G 308
++ +KS E ++ +++ ++ +QA K++G +FK GKY +A+ Y + G
Sbjct: 244 EVTLKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYG 303
Query: 309 IAADGANA----LLPA--NRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTF 362
++ + A LL A N AM YLK+++Y +A + C +A+ LD + K RRG A+
Sbjct: 304 LSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLL 363
Query: 363 LGKLNEAKQDFETVLLLEPGNKQAVTELSKIKKK 396
+ + AK DFE VL + P NK A ++S +KK
Sbjct: 364 MNEFESAKGDFEKVLEVNPQNKAARLQISMCQKK 397
Score = 68.2 bits (165), Expect = 2e-11
Identities = 54/192 (28%), Positives = 91/192 (47%), Gaps = 19/192 (9%)
Query: 111 THESLSQESESEEDGIHVDSQKALVLKEKGNKYFKQGKYDEAIDCYTKGMD--------- 161
T +S + ES E ++A ++KEKG YFK GKY +A+ Y K +
Sbjct: 246 TLKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYGLS 305
Query: 162 ------ADPYNPVLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQ 215
++ + N A Y +L+++ A C+ A+ L+ + K RRG A+ +
Sbjct: 306 EKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMN 365
Query: 216 KLEEAKKDYERVLELEPNNFEATNELRKISQALASKENSYPKE--ADIVIKSTEGERKQI 273
+ E AK D+E+VLE+ P N A ++ + Q A + N + A++ K E + K+
Sbjct: 366 EFESAKGDFEKVLEVNPQNKAARLQI-SMCQKKAKEHNERDRRIYANMFKKFAEQDAKE- 423
Query: 274 EAQQNKQQAISE 285
EA + + SE
Sbjct: 424 EANKAMGKKTSE 435
>gi|4758384 FK506 binding protein 5 isoform 1 [Homo sapiens]
Length = 457
Score = 76.3 bits (186), Expect = 8e-14
Identities = 50/154 (32%), Positives = 85/154 (55%), Gaps = 17/154 (11%)
Query: 260 DIVIKSTEGERK--QIEAQQNKQQAISEKDRGNGFFKEGKYERAIECYTR---------G 308
++ +KS E ++ +++ ++ +QA K++G +FK GKY +A+ Y + G
Sbjct: 244 EVTLKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYG 303
Query: 309 IAADGANA----LLPA--NRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTF 362
++ + A LL A N AM YLK+++Y +A + C +A+ LD + K RRG A+
Sbjct: 304 LSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLL 363
Query: 363 LGKLNEAKQDFETVLLLEPGNKQAVTELSKIKKK 396
+ + AK DFE VL + P NK A ++S +KK
Sbjct: 364 MNEFESAKGDFEKVLEVNPQNKAARLQISMCQKK 397
Score = 68.2 bits (165), Expect = 2e-11
Identities = 54/192 (28%), Positives = 91/192 (47%), Gaps = 19/192 (9%)
Query: 111 THESLSQESESEEDGIHVDSQKALVLKEKGNKYFKQGKYDEAIDCYTKGMD--------- 161
T +S + ES E ++A ++KEKG YFK GKY +A+ Y K +
Sbjct: 246 TLKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYGLS 305
Query: 162 ------ADPYNPVLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQ 215
++ + N A Y +L+++ A C+ A+ L+ + K RRG A+ +
Sbjct: 306 EKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMN 365
Query: 216 KLEEAKKDYERVLELEPNNFEATNELRKISQALASKENSYPKE--ADIVIKSTEGERKQI 273
+ E AK D+E+VLE+ P N A ++ + Q A + N + A++ K E + K+
Sbjct: 366 EFESAKGDFEKVLEVNPQNKAARLQI-SMCQKKAKEHNERDRRIYANMFKKFAEQDAKE- 423
Query: 274 EAQQNKQQAISE 285
EA + + SE
Sbjct: 424 EANKAMGKKTSE 435
>gi|221219056 DnaJ (Hsp40) homolog, subfamily C, member 7 isoform 2
[Homo sapiens]
Length = 438
Score = 75.1 bits (183), Expect = 2e-13
Identities = 62/194 (31%), Positives = 92/194 (47%), Gaps = 12/194 (6%)
Query: 113 ESLSQESESEEDGIHVDSQKAL-VLKEKGNKYFKQGKYDEAIDCYTKGMDADPYN----P 167
++L + E+ I + KAL KE GNK FK+G Y A + YT+ + DP N
Sbjct: 179 QALRMAPDHEKACIACRNAKALKAKKEDGNKAFKEGNYKLAYELYTEALGIDPNNIKTNA 238
Query: 168 VLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERV 227
L NR + +L+K A DC AV L+ +Y KAY RR ++ EEA +DYE+V
Sbjct: 239 KLYCNRGTVNSKLRKLDDAIEDCTNAVKLDDTYIKAYLRRAQCYMDTEQYEEAVRDYEKV 298
Query: 228 LELEPNNFEATNELRKISQ--ALASKENSYPKEADIVIKSTEGERKQIEAQQNKQQAISE 285
+ E + +L K +Q SK Y K + ++E E I+ K+ +
Sbjct: 299 YQTEKT--KEHKQLLKNAQLELKKSKRKDYYKILGVDKNASEDE---IKKAYRKRALMHH 353
Query: 286 KDRGNGFFKEGKYE 299
DR +G E + E
Sbjct: 354 PDRHSGASAEVQKE 367
Score = 74.7 bits (182), Expect = 2e-13
Identities = 49/150 (32%), Positives = 72/150 (48%), Gaps = 10/150 (6%)
Query: 263 IKSTEGERKQIEAQQNKQQAISEKDRGNGFFKEGKYERAIECYTRGIAADG----ANALL 318
++ K A +N + ++K+ GN FKEG Y+ A E YT + D NA L
Sbjct: 181 LRMAPDHEKACIACRNAKALKAKKEDGNKAFKEGNYKLAYELYTEALGIDPNNIKTNAKL 240
Query: 319 PANRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLL 378
NR K++K ++A +DCT A+ LD +Y KA+ RR + EA +D+E V
Sbjct: 241 YCNRGTVNSKLRKLDDAIEDCTNAVKLDDTYIKAYLRRAQCYMDTEQYEEAVRDYEKVYQ 300
Query: 379 LEPGN------KQAVTELSKIKKKPLKKVI 402
E K A EL K K+K K++
Sbjct: 301 TEKTKEHKQLLKNAQLELKKSKRKDYYKIL 330
Score = 53.1 bits (126), Expect = 7e-07
Identities = 60/292 (20%), Positives = 107/292 (36%), Gaps = 43/292 (14%)
Query: 164 PYNPVLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKD 223
P N NRA+ L +F A D +V L+ S+ + + R G +L A +
Sbjct: 3 PKNASYYGNRAATLMMLGRFREALGDAQQSVRLDDSFVRGHLREGKCHLSLGNAMAACRS 62
Query: 224 YERVLELEPNNFEATNELRKISQALASKENSYPKEADIVIKSTEGERKQIEAQQNKQQAI 283
++R LEL+ N +A E + + + + + I
Sbjct: 63 FQRALELDHKNAQAQQEFKNANAVM------------------------------EYEKI 92
Query: 284 SEKDRGNGFFKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAI 343
+E D F++ + + + C R + A +A + +Y EA+ + +
Sbjct: 93 AETD-----FEKRDFRKVVFCMDRALEFAPACHRFKILKAECLAMLGRYPEAQSVASDIL 147
Query: 344 LLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLEPGNKQAV-----TELSKIKKKPL 398
+D + + A RG + + +A Q F L + P +++A + K KK+
Sbjct: 148 RMDSTNADALYVRGLCLYYEDCIEKAVQFFVQALRMAPDHEKACIACRNAKALKAKKEDG 207
Query: 399 KKVIIEETGNLIQTIDVPDSTTAAAPENNPINLANVIAATGTTSKKNSSQDD 450
K E GN ++ P N N A + GT + K DD
Sbjct: 208 NKAFKE--GNYKLAYELYTEALGIDPNNIKTN-AKLYCNRGTVNSKLRKLDD 256
>gi|4503729 FK506 binding protein 52 [Homo sapiens]
Length = 459
Score = 73.9 bits (180), Expect = 4e-13
Identities = 49/163 (30%), Positives = 88/163 (53%), Gaps = 17/163 (10%)
Query: 260 DIVIKSTEGERK--QIEAQQNKQQAISEKDRGNGFFKEGKYERAIECYTRGIA------- 310
++ +KS E ++ ++ +++ +Q+ K+RG +FKEGKY++A+ Y + ++
Sbjct: 246 ELHLKSFEKAKESWEMNSEEKLEQSTIVKERGTVYFKEGKYKQALLQYKKIVSWLEYESS 305
Query: 311 -----ADGANALLPA---NRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTF 362
A A AL A N AM +LK+Q + A + C +A+ LD + K RRG A
Sbjct: 306 FSNEEAQKAQALRLASHLNLAMCHLKLQAFSAAIESCNKALELDSNNEKGLFRRGEAHLA 365
Query: 363 LGKLNEAKQDFETVLLLEPGNKQAVTELSKIKKKPLKKVIIEE 405
+ A+ DF+ VL L P NK A T+L+ +++ +++ E+
Sbjct: 366 VNDFELARADFQKVLQLYPNNKAAKTQLAVCQQRIRRQLAREK 408
Score = 71.6 bits (174), Expect = 2e-12
Identities = 51/178 (28%), Positives = 84/178 (47%), Gaps = 22/178 (12%)
Query: 113 ESLSQESESEEDGIHVDSQKALVLKEKGNKYFKQGKYDEAIDCYTK-------------- 158
+S + ES E +++ ++KE+G YFK+GKY +A+ Y K
Sbjct: 250 KSFEKAKESWEMNSEEKLEQSTIVKERGTVYFKEGKYKQALLQYKKIVSWLEYESSFSNE 309
Query: 159 -GMDADPYNPVLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKL 217
A N A + +L+ F+ A CN A+ L+ + K RRG A A+
Sbjct: 310 EAQKAQALRLASHLNLAMCHLKLQAFSAAIESCNKALELDSNNEKGLFRRGEAHLAVNDF 369
Query: 218 EEAKKDYERVLELEPNNFEATNEL----RKISQALASKENSYPKEADIVIKSTEGERK 271
E A+ D+++VL+L PNN A +L ++I + LA ++ Y A++ + E E K
Sbjct: 370 ELARADFQKVLQLYPNNKAAKTQLAVCQQRIRRQLAREKKLY---ANMFERLAEEENK 424
>gi|224028289 tetratricopeptide repeat domain 28 [Homo sapiens]
Length = 2481
Score = 70.1 bits (170), Expect = 6e-12
Identities = 43/153 (28%), Positives = 78/153 (50%)
Query: 266 TEGERKQIEAQQNKQQAISEKDRGNGFFKEGKYERAIECYTRGIAADGANALLPANRAMA 325
T G+R +K + + + + N +G + AI Y +A D N +L +NR+ A
Sbjct: 42 TIGQRSPDGPVLSKAEFVEKVRQSNQACHDGDFHTAIVLYNEALAVDPQNCILYSNRSAA 101
Query: 326 YLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLEPGNKQ 385
Y+KIQ+Y++A D +A LL+ + KA+ R+G A +LG+ +A F + L +P + Q
Sbjct: 102 YMKIQQYDKALDDAIKARLLNPKWPKAYFRQGVALQYLGRHADALAAFASGLAQDPKSLQ 161
Query: 386 AVTELSKIKKKPLKKVIIEETGNLIQTIDVPDS 418
+ + + K + +E T +Q + + S
Sbjct: 162 LLVGMVEAAMKSPMRDSLEPTYQQLQKMKLDKS 194
Score = 49.3 bits (116), Expect = 1e-05
Identities = 28/98 (28%), Positives = 50/98 (51%)
Query: 139 KGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRLKKFAVAESDCNLAVALNR 198
+ N+ G + AI Y + + DP N +L +NR++AY +++++ A D A LN
Sbjct: 64 QSNQACHDGDFHTAIVLYNEALAVDPQNCILYSNRSAAYMKIQQYDKALDDAIKARLLNP 123
Query: 199 SYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNFE 236
+ KAY R+G A L + +A + L +P + +
Sbjct: 124 KWPKAYFRQGVALQYLGRHADALAAFASGLAQDPKSLQ 161
Score = 37.0 bits (84), Expect = 0.055
Identities = 68/298 (22%), Positives = 116/298 (38%), Gaps = 39/298 (13%)
Query: 143 YFKQGKYDEAIDCYTKGMD-----------ADPYNPVLPT-------NRASAYFRLKKFA 184
Y GKY A CY + +D A Y + T A YF +
Sbjct: 804 YMALGKYTMAFKCYEEQLDLGQKLKDPSLEAQVYGNMGITKMNMNVMEEAIGYFEQQLAM 863
Query: 185 VAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNFEATNELRKI 244
+ + N +V L+R +AY G AL EEA K YE+ L + ++ N ++
Sbjct: 864 LQQLSGNESV-LDRG--RAYGNLGDCYEALGDYEEAIKYYEQYLSVA----QSLNRMQDQ 916
Query: 245 SQALASKENSYPKEADIVIKSTEGERKQIEAQQ-----NKQQAISEKDRGNGFFKEGKYE 299
++A N + + E++ + A + NK QA E G+ + G YE
Sbjct: 917 AKAYRGLGNGHRAMGSLQQALVCFEKRLVVAHELGEAFNKAQAYGE--LGSLHSQLGNYE 974
Query: 300 RAIECYTR--GIAADGANALLPANRAM----AYLKIQKYEEAEKDCTQAILLDGSYSKAF 353
+AI C R IA D + L ++ A Y ++ +Y+ A Q L +
Sbjct: 975 QAISCLERQLNIARDMKDRALESDAACGLGGVYQQMGEYDTA-LQYHQLDLQIAEETNNP 1033
Query: 354 ARRGTARTFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIKKKPLKKVIIEETGNLIQ 411
+G A LG E+ FE ++ + + +++ + K + + T + +Q
Sbjct: 1034 TCQGRAYGNLGLTYESLGTFERAVVYQEQHLSIAAQMNDLAAKTVSYSSLGRTHHALQ 1091
>gi|89179321 smooth muscle cell associated protein-1 isoform 3 [Homo
sapiens]
Length = 929
Score = 68.9 bits (167), Expect = 1e-11
Identities = 43/119 (36%), Positives = 63/119 (52%), Gaps = 3/119 (2%)
Query: 286 KDRGNGFFKEGKYERAIECYTRGIAADGA---NALLPANRAMAYLKIQKYEEAEKDCTQA 342
+ GN FK G Y A+ YT+ + D A+L NRA +LK++ Y++AE + ++A
Sbjct: 10 RKEGNELFKCGDYGGALAAYTQALGLDATPQDQAVLHRNRAACHLKLEDYDKAETEASKA 69
Query: 343 ILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIKKKPLKKV 401
I DG KA RR A LG+L++A D + + LEP NK L I + +KV
Sbjct: 70 IEKDGGDVKALYRRSQALEKLGRLDQAVLDLQRCVSLEPKNKVFQEALRNIGGQIQEKV 128
Score = 66.2 bits (160), Expect = 8e-11
Identities = 50/165 (30%), Positives = 81/165 (49%), Gaps = 12/165 (7%)
Query: 136 LKEKGNKYFKQGKYDEAIDCYTK--GMDADPYN-PVLPTNRASAYFRLKKFAVAESDCNL 192
L+++GN+ FK G Y A+ YT+ G+DA P + VL NRA+ + +L+ + AE++ +
Sbjct: 9 LRKEGNELFKCGDYGGALAAYTQALGLDATPQDQAVLHRNRAACHLKLEDYDKAETEASK 68
Query: 193 AVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNFEATNELRKISQALASKE 252
A+ + KA RR A L +L++A D +R + LEP N LR I + K
Sbjct: 69 AIEKDGGDVKALYRRSQALEKLGRLDQAVLDLQRCVSLEPKNKVFQEALRNIGGQIQEKV 128
Query: 253 NSYPKEADIVIKS-----TEGERKQIEAQQNKQQ---AISEKDRG 289
Y D ++ + E K E +Q Q ++ +D G
Sbjct: 129 R-YMSSTDAKVEQMFQILLDPEEKGTEKKQKASQNLVVLAREDAG 172
>gi|29725607 smooth muscle cell associated protein-1 isoform 2 [Homo
sapiens]
Length = 944
Score = 68.9 bits (167), Expect = 1e-11
Identities = 43/119 (36%), Positives = 63/119 (52%), Gaps = 3/119 (2%)
Query: 286 KDRGNGFFKEGKYERAIECYTRGIAADGA---NALLPANRAMAYLKIQKYEEAEKDCTQA 342
+ GN FK G Y A+ YT+ + D A+L NRA +LK++ Y++AE + ++A
Sbjct: 25 RKEGNELFKCGDYGGALAAYTQALGLDATPQDQAVLHRNRAACHLKLEDYDKAETEASKA 84
Query: 343 ILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIKKKPLKKV 401
I DG KA RR A LG+L++A D + + LEP NK L I + +KV
Sbjct: 85 IEKDGGDVKALYRRSQALEKLGRLDQAVLDLQRCVSLEPKNKVFQEALRNIGGQIQEKV 143
Score = 66.2 bits (160), Expect = 8e-11
Identities = 50/165 (30%), Positives = 81/165 (49%), Gaps = 12/165 (7%)
Query: 136 LKEKGNKYFKQGKYDEAIDCYTK--GMDADPYN-PVLPTNRASAYFRLKKFAVAESDCNL 192
L+++GN+ FK G Y A+ YT+ G+DA P + VL NRA+ + +L+ + AE++ +
Sbjct: 24 LRKEGNELFKCGDYGGALAAYTQALGLDATPQDQAVLHRNRAACHLKLEDYDKAETEASK 83
Query: 193 AVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNFEATNELRKISQALASKE 252
A+ + KA RR A L +L++A D +R + LEP N LR I + K
Sbjct: 84 AIEKDGGDVKALYRRSQALEKLGRLDQAVLDLQRCVSLEPKNKVFQEALRNIGGQIQEKV 143
Query: 253 NSYPKEADIVIKS-----TEGERKQIEAQQNKQQ---AISEKDRG 289
Y D ++ + E K E +Q Q ++ +D G
Sbjct: 144 R-YMSSTDAKVEQMFQILLDPEEKGTEKKQKASQNLVVLAREDAG 187
>gi|5453980 DnaJ (Hsp40) homolog, subfamily C, member 3 [Homo
sapiens]
Length = 504
Score = 67.4 bits (163), Expect = 4e-11
Identities = 74/301 (24%), Positives = 123/301 (40%), Gaps = 38/301 (12%)
Query: 120 ESEEDGIHVDSQKALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFR 179
E E G++ D +K L E G K G+ +A+ + +D DP N + RA+ +
Sbjct: 27 EGAECGVNADVEKHL---ELGKKLLAAGQLADALSQFHAAVDGDPDNYIAYYRRATVFLA 83
Query: 180 LKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNFEATN 239
+ K A D + L +T A +RG KL+EA+ D+++VL+ P+
Sbjct: 84 MGKSKAALPDLTKVIQLKMDFTAARLQRGHLLLKQGKLDEAEDDFKKVLKSNPS------ 137
Query: 240 ELRKISQALASKENSYPKEADIVIKSTEGERKQIEAQQNKQQAISEKDRGNGFFKEGKYE 299
EN + +IKS E Q+ + QA++ F G Y
Sbjct: 138 ------------ENEEKEAQSQLIKSD-------EMQRLRSQALNA-------FGSGDYT 171
Query: 300 RAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTA 359
AI + + +A L RA ++K + +A D A L ++AF + T
Sbjct: 172 AAIAFLDKILEVCVWDAELRELRAECFIKEGEPRKAISDLKAASKLKNDNTEAFYKISTL 231
Query: 360 RTFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIKKKPLKKVIIEETGNLIQTIDVPDST 419
LG + + L L+ +K+ ++KK L K +IE LI+ D+T
Sbjct: 232 YYQLGDHELSLSEVRECLKLDQDHKRCFAHYKQVKK--LNK-LIESAEELIRDGRYTDAT 288
Query: 420 T 420
+
Sbjct: 289 S 289
Score = 36.2 bits (82), Expect = 0.094
Identities = 55/298 (18%), Positives = 115/298 (38%), Gaps = 33/298 (11%)
Query: 98 VDRILDELDKDDSTHESLSQESESEEDGIHVDSQKALVLKEKGNKYFKQGKYDEAIDCYT 157
+D D+ K ++ S ++E E++ I D + L + + F G Y AI
Sbjct: 121 LDEAEDDFKKVLKSNPSENEEKEAQSQLIKSDEMQRL--RSQALNAFGSGDYTAAIAFLD 178
Query: 158 KGMDADPYNPVLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKL 217
K ++ ++ L RA + + + A SD A L T+A+ + + L
Sbjct: 179 KILEVCVWDAELRELRAECFIKEGEPRKAISDLKAASKLKNDNTEAFYKISTLYYQLGDH 238
Query: 218 EEAKKDYERVLELEPNNFEATNELRKISQALASKENSYPKEADIVIKSTEGERKQIEAQQ 277
E + + L+L+ ++ +++ K N + A+ +I+ + + +A
Sbjct: 239 ELSLSEVRECLKLDQDHKRCFAHYKQVK-----KLNKLIESAEELIR----DGRYTDAT- 288
Query: 278 NKQQAISEKDRGNGFFKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEK 337
+K +++ + + + ER C++ K +K EA +
Sbjct: 289 SKYESVMKTEPSIAEYTVRSKERICHCFS---------------------KDEKPVEAIR 327
Query: 338 DCTQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIKK 395
C++ + ++ A R A +EA QD+ET ++Q L K ++
Sbjct: 328 VCSEVLQMEPDNVNALKDRAEAYLIEEMYDEAIQDYETAQEHNENDQQIREGLEKAQR 385
Score = 31.6 bits (70), Expect = 2.3
Identities = 41/198 (20%), Positives = 73/198 (36%), Gaps = 8/198 (4%)
Query: 68 KAKESSKKTREENTKNRIKSYDYEAWAKLDV--DRILDELDKDDSTHESLSQESESEEDG 125
K E K + +++K+ + EA+ K+ ++ D E L + + +
Sbjct: 200 KEGEPRKAISDLKAASKLKNDNTEAFYKISTLYYQLGDHELSLSEVRECLKLDQDHKRCF 259
Query: 126 IHVDSQKAL-VLKEKGNKYFKQGKYDEAIDCYTKGMDADP----YNPVLPTNRASAYFRL 180
H K L L E + + G+Y +A Y M +P Y + +
Sbjct: 260 AHYKQVKKLNKLIESAEELIRDGRYTDATSKYESVMKTEPSIAEYTVRSKERICHCFSKD 319
Query: 181 KKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNFEATNE 240
+K A C+ + + A R A + +EA +DYE E N+ +
Sbjct: 320 EKPVEAIRVCSEVLQMEPDNVNALKDRAEAYLIEEMYDEAIQDYETAQEHNENDQQIREG 379
Query: 241 LRKISQAL-ASKENSYPK 257
L K + L S++ Y K
Sbjct: 380 LEKAQRLLKQSQKRDYYK 397
>gi|75750484 cardiomyopathy associated 4 isoform 2 [Homo sapiens]
Length = 929
Score = 64.7 bits (156), Expect = 2e-10
Identities = 40/123 (32%), Positives = 66/123 (53%), Gaps = 3/123 (2%)
Query: 132 KALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPT---NRASAYFRLKKFAVAES 188
+A+ LKE+GN++F+ Y A + Y++ + +L T NRA+ + + + A S
Sbjct: 5 EAVQLKEEGNRHFQLQDYKAATNSYSQALKLTKDKALLATLYRNRAACGLKTESYVQAAS 64
Query: 189 DCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNFEATNELRKISQAL 248
D + A+ +N S KA RR A L KL++A KD +R LEP N LR+++ ++
Sbjct: 65 DASRAIDINSSDIKALYRRCQALEHLGKLDQAFKDVQRCATLEPRNQNFQEMLRRLNTSI 124
Query: 249 ASK 251
K
Sbjct: 125 QEK 127
Score = 59.3 bits (142), Expect = 1e-08
Identities = 39/127 (30%), Positives = 64/127 (50%), Gaps = 3/127 (2%)
Query: 281 QAISEKDRGNGFFKEGKYERAIECYTRGIAADGANALLPA---NRAMAYLKIQKYEEAEK 337
+A+ K+ GN F+ Y+ A Y++ + ALL NRA LK + Y +A
Sbjct: 5 EAVQLKEEGNRHFQLQDYKAATNSYSQALKLTKDKALLATLYRNRAACGLKTESYVQAAS 64
Query: 338 DCTQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIKKKP 397
D ++AI ++ S KA RR A LGKL++A +D + LEP N+ L ++
Sbjct: 65 DASRAIDINSSDIKALYRRCQALEHLGKLDQAFKDVQRCATLEPRNQNFQEMLRRLNTSI 124
Query: 398 LKKVIIE 404
+K+ ++
Sbjct: 125 QEKLRVQ 131
>gi|27477061 cardiomyopathy associated 4 isoform 1 [Homo sapiens]
Length = 931
Score = 64.7 bits (156), Expect = 2e-10
Identities = 40/123 (32%), Positives = 66/123 (53%), Gaps = 3/123 (2%)
Query: 132 KALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPT---NRASAYFRLKKFAVAES 188
+A+ LKE+GN++F+ Y A + Y++ + +L T NRA+ + + + A S
Sbjct: 5 EAVQLKEEGNRHFQLQDYKAATNSYSQALKLTKDKALLATLYRNRAACGLKTESYVQAAS 64
Query: 189 DCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNFEATNELRKISQAL 248
D + A+ +N S KA RR A L KL++A KD +R LEP N LR+++ ++
Sbjct: 65 DASRAIDINSSDIKALYRRCQALEHLGKLDQAFKDVQRCATLEPRNQNFQEMLRRLNTSI 124
Query: 249 ASK 251
K
Sbjct: 125 QEK 127
Score = 59.3 bits (142), Expect = 1e-08
Identities = 39/127 (30%), Positives = 64/127 (50%), Gaps = 3/127 (2%)
Query: 281 QAISEKDRGNGFFKEGKYERAIECYTRGIAADGANALLPA---NRAMAYLKIQKYEEAEK 337
+A+ K+ GN F+ Y+ A Y++ + ALL NRA LK + Y +A
Sbjct: 5 EAVQLKEEGNRHFQLQDYKAATNSYSQALKLTKDKALLATLYRNRAACGLKTESYVQAAS 64
Query: 338 DCTQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIKKKP 397
D ++AI ++ S KA RR A LGKL++A +D + LEP N+ L ++
Sbjct: 65 DASRAIDINSSDIKALYRRCQALEHLGKLDQAFKDVQRCATLEPRNQNFQEMLRRLNTSI 124
Query: 398 LKKVIIE 404
+K+ ++
Sbjct: 125 QEKLRVQ 131
>gi|75677570 dyslexia susceptibility 1 candidate 1 isoform a [Homo
sapiens]
Length = 420
Score = 62.0 bits (149), Expect = 2e-09
Identities = 66/265 (24%), Positives = 113/265 (42%), Gaps = 18/265 (6%)
Query: 4 ANKAIELQLQVKQNAEELQDFMRD--LENWEKDIKQKDMELRRQN---GVPEENLPPIRN 58
A KA+E + ++ AEE + R+ L EK IK++ +++ ++ + NL P +
Sbjct: 155 ATKALEAWKEYQRKAEEQKKIQREEKLCQKEKQIKEERKKIKYKSLTRNLASRNLAP-KG 213
Query: 59 GNFRKKKKGKAKESSKKTREENTKNRIKSYDYEAWAKLDVDRILDE---LDKDDSTHESL 115
N K KE S +I L ++ +E L K ++
Sbjct: 214 RNSENIFTEKLKEDSIPAPRSVGSIKINFTPRVFPTALRESQVAEEEEWLHKQAEARRAM 273
Query: 116 SQESESEEDGIHVDSQKALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRAS 175
+ + +E + + + LK+KGNK F Y AI+ Y + + P+L NRA+
Sbjct: 274 NTDI-AELCDLKEEEKNPEWLKDKGNKLFATENYLAAINAYNLAIRLNNKMPLLYLNRAA 332
Query: 176 AYFRLKKFAVAESDCNLAVAL--------NRSYTKAYSRRGAARFALQKLEEAKKDYERV 227
+ +LK A D + A+ L + KA+ RRG A L+ E +DYE
Sbjct: 333 CHLKLKNLHKAIEDSSKALELLMPPVTDNANARMKAHVRRGTAFCQLELYVEGLQDYEAA 392
Query: 228 LELEPNNFEATNELRKISQALASKE 252
L+++P+N + KI + E
Sbjct: 393 LKIDPSNKIVQIDAEKIRNVIQGTE 417
Score = 58.9 bits (141), Expect = 1e-08
Identities = 47/155 (30%), Positives = 67/155 (43%), Gaps = 22/155 (14%)
Query: 262 VIKSTEGERKQIEAQQNKQQAISE--------------KDRGNGFFKEGKYERAIECYTR 307
V + E KQ EA++ I+E KD+GN F Y AI Y
Sbjct: 256 VAEEEEWLHKQAEARRAMNTDIAELCDLKEEEKNPEWLKDKGNKLFATENYLAAINAYNL 315
Query: 308 GIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAILL--------DGSYSKAFARRGTA 359
I + LL NRA +LK++ +A +D ++A+ L + KA RRGTA
Sbjct: 316 AIRLNNKMPLLYLNRAACHLKLKNLHKAIEDSSKALELLMPPVTDNANARMKAHVRRGTA 375
Query: 360 RTFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIK 394
L E QD+E L ++P NK + KI+
Sbjct: 376 FCQLELYVEGLQDYEAALKIDPSNKIVQIDAEKIR 410
>gi|17149853 WAF-1/CIP1 stabilizing protein 39 [Homo sapiens]
Length = 349
Score = 62.0 bits (149), Expect = 2e-09
Identities = 38/130 (29%), Positives = 61/130 (46%), Gaps = 8/130 (6%)
Query: 272 QIEAQQNKQQAISEKDRGNGFFKEGKYERAIECYTRGIA--------ADGANALLPANRA 323
++E + + A E+ RG F+ G E A CY R + +L AN A
Sbjct: 200 ELETSEKEALAREERARGTELFRAGNPEGAARCYGRALRLLLTLPPPGPPERTVLHANLA 259
Query: 324 MAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLEPGN 383
L + + + A + C + + + + KA RRG A+ LG L +A D + VL ++P N
Sbjct: 260 ACQLLLGQPQLAAQSCDRVLEREPGHLKALYRRGVAQAALGNLEKATADLKKVLAIDPKN 319
Query: 384 KQAVTELSKI 393
+ A EL K+
Sbjct: 320 RAAQEELGKV 329
Score = 56.2 bits (134), Expect = 9e-08
Identities = 42/144 (29%), Positives = 67/144 (46%), Gaps = 12/144 (8%)
Query: 111 THESLSQESESEEDGIHVDSQKALVLKEK--GNKYFKQGKYDEAIDCYTKGM-------- 160
T S +Q +S E + ++AL +E+ G + F+ G + A CY + +
Sbjct: 188 TLASFTQGRDSWE--LETSEKEALAREERARGTELFRAGNPEGAARCYGRALRLLLTLPP 245
Query: 161 DADPYNPVLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEA 220
P VL N A+ L + +A C+ + + KA RRG A+ AL LE+A
Sbjct: 246 PGPPERTVLHANLAACQLLLGQPQLAAQSCDRVLEREPGHLKALYRRGVAQAALGNLEKA 305
Query: 221 KKDYERVLELEPNNFEATNELRKI 244
D ++VL ++P N A EL K+
Sbjct: 306 TADLKKVLAIDPKNRAAQEELGKV 329
>gi|56181387 STIP1 homology and U-box containing protein 1 [Homo
sapiens]
Length = 303
Score = 59.3 bits (142), Expect = 1e-08
Identities = 33/101 (32%), Positives = 52/101 (51%)
Query: 130 SQKALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRLKKFAVAESD 189
S A LKE+GN+ F KY EA CY + + +P V TNRA Y ++++ A +D
Sbjct: 23 SPSAQELKEQGNRLFVGRKYPEAAACYGRAITRNPLVAVYYTNRALCYLKMQQHEQALAD 82
Query: 190 CNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLEL 230
C A+ L+ KA+ G + ++ +EA + +R L
Sbjct: 83 CRRALELDGQSVKAHFFLGQCQLEMESYDEAIANLQRAYSL 123
Score = 58.5 bits (140), Expect = 2e-08
Identities = 32/84 (38%), Positives = 46/84 (54%)
Query: 286 KDRGNGFFKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAILL 345
K++GN F KY A CY R I + A+ NRA+ YLK+Q++E+A DC +A+ L
Sbjct: 30 KEQGNRLFVGRKYPEAAACYGRAITRNPLVAVYYTNRALCYLKMQQHEQALADCRRALEL 89
Query: 346 DGSYSKAFARRGTARTFLGKLNEA 369
DG KA G + + +EA
Sbjct: 90 DGQSVKAHFFLGQCQLEMESYDEA 113
>gi|239756104 PREDICTED: tetratricopeptide repeat domain 6 [Homo
sapiens]
Length = 1614
Score = 58.9 bits (141), Expect = 1e-08
Identities = 35/120 (29%), Positives = 59/120 (49%)
Query: 112 HESLSQESESEEDGIHVDSQKALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPT 171
H SQ S+ + D + VL + KY+EA + + +++ P+ +
Sbjct: 1489 HRQFSQASDYFSKALKFDPENEYVLMNRAITNTILKKYEEAKEDFANVIESCPFWAAVYF 1548
Query: 172 NRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELE 231
NRA Y+ LK++ +AE D N A++L + Y+ R R + +EEA DY + L+LE
Sbjct: 1549 NRAHFYYCLKQYELAEEDLNKALSLKPNDALVYNFRAKVRGKIGLIEEAMADYNQALDLE 1608
Score = 54.7 bits (130), Expect = 3e-07
Identities = 33/122 (27%), Positives = 58/122 (47%)
Query: 123 EDGIHVDSQKALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRLKK 182
+D I ++ + +L GN YF ++ +A D ++K + DP N + NRA LKK
Sbjct: 1466 QDAITLNPKYSLAYFNAGNIYFHHRQFSQASDYFSKALKFDPENEYVLMNRAITNTILKK 1525
Query: 183 FAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNFEATNELR 242
+ A+ D + + Y R + L++ E A++D + L L+PN+ N
Sbjct: 1526 YEEAKEDFANVIESCPFWAAVYFNRAHFYYCLKQYELAEEDLNKALSLKPNDALVYNFRA 1585
Query: 243 KI 244
K+
Sbjct: 1586 KV 1587
Score = 53.1 bits (126), Expect = 7e-07
Identities = 57/305 (18%), Positives = 115/305 (37%), Gaps = 50/305 (16%)
Query: 113 ESLSQESESEEDGIHVDSQKALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTN 172
E+ Q + +H++ G QGK+ +A + +T +D DP N +
Sbjct: 1355 EATKQAQKDFLKALHINPAYIKARISFGYNLQAQGKFQKAWNHFTIAIDTDPKNYLAYEG 1414
Query: 173 RASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEP 232
RA ++ A D N A+ ++ + + + RG + + A KDY+ + L P
Sbjct: 1415 RAVVCLQMGNNFAAMQDINAAMKISTT-AEFLTNRGVIHEFMGHKQNAMKDYQDAITLNP 1473
Query: 233 NNFEATNELRKISQALASKENSYPKEADIVIKSTEGERKQIEAQQNKQQAISEKDRGNGF 292
+ +++ + GN +
Sbjct: 1474 -----------------------------------------------KYSLAYFNAGNIY 1486
Query: 293 FKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAILLDGSYSKA 352
F ++ +A + +++ + D N + NRA+ ++KYEEA++D I ++
Sbjct: 1487 FHHRQFSQASDYFSKALKFDPENEYVLMNRAITNTILKKYEEAKEDFANVIESCPFWAAV 1546
Query: 353 FARRGTARTFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIKKKPLKKVIIEETGNLIQT 412
+ R L + A++D L L+P + +K++ K +I E + Q
Sbjct: 1547 YFNRAHFYYCLKQYELAEEDLNKALSLKPNDALVYNFRAKVRGK--IGLIEEAMADYNQA 1604
Query: 413 IDVPD 417
+D+ D
Sbjct: 1605 LDLED 1609
Score = 41.2 bits (95), Expect = 0.003
Identities = 65/292 (22%), Positives = 116/292 (39%), Gaps = 61/292 (20%)
Query: 143 YFKQGKYDE------AIDCYTKGMDADPYNPVLPTNRASAYFRLKKFAVAESDCNLAVAL 196
YF++G+ E AID ++K + DP R Y + + A D + +
Sbjct: 1022 YFRRGEMYEITNKVLAIDDFSKCIFYDPKRTDALLKRGLFYCENENWFAAIEDFTALLNI 1081
Query: 197 NRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNFEATNELRKISQALASKENSYP 256
+ ++A RG ++ + AK ++ E++ + +EL + QAL S+
Sbjct: 1082 DHQNSQA---RGQYLLMMKYYDLAKFTIYQIAEMD----KGLSELSPMQQALIY---SFC 1131
Query: 257 KEADIVIKSTEG--------------ERKQIEAQQNKQ---------QAISEKDRGNG-- 291
+ D I+ +G + Q++A++ K+ A S D+G
Sbjct: 1132 ENHDKAIEVLDGISWNRAEMTMCALLAKVQMKAKRTKEAVEVLKKALDASSHSDKGPDAT 1191
Query: 292 -------------FFKEGK----YERAIECYTRGIAADGANALLPANRAMAYLKIQKYEE 334
+ +EG Y+ AI T I+ D + + NRA+ Y KI++ +
Sbjct: 1192 TISADCLYNLGLCYMEEGNLQMTYKLAITDLTTAISMDKNSYIAFYNRALCYTKIRELQM 1251
Query: 335 AEKDCTQAILLDGSYS---KAFARRGTARTFLGKLNEAKQDFETVLLLEPGN 383
A D +LLD + + F RG LG+ A +DF+ L+ N
Sbjct: 1252 ALTDYGIVLLLDATETVKLNTFLNRGLIYVELGQYGFALEDFKQAALISRTN 1303
Score = 36.6 bits (83), Expect = 0.072
Identities = 47/174 (27%), Positives = 76/174 (43%), Gaps = 28/174 (16%)
Query: 203 AYSRRGAARFALQKLEEAKKDYERVLELEP---NNF--------------EATNELRKIS 245
AY RRGA L KL+ A D +RV+ LEP N + EA ++L I
Sbjct: 919 AYCRRGAIYRKLGKLQSAMNDLQRVILLEPLFLNAYWHRHLIYLFQDKINEALDDLNYIH 978
Query: 246 QALASKENSYPKEADIVIKSTEGERKQIEAQQNKQQAI-SEKDRGNGFFKEGK-YE---- 299
+ + +Y +A+I G++ A N QAI S + +F+ G+ YE
Sbjct: 979 KYNKNNTEAYLSKAEIY----RGKKDITLAILNYTQAIKSTPTDADIYFRRGEMYEITNK 1034
Query: 300 -RAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAILLDGSYSKA 352
AI+ +++ I D R + Y + + + A +D T + +D S+A
Sbjct: 1035 VLAIDDFSKCIFYDPKRTDALLKRGLFYCENENWFAAIEDFTALLNIDHQNSQA 1088
Score = 34.7 bits (78), Expect = 0.27
Identities = 25/98 (25%), Positives = 46/98 (46%), Gaps = 3/98 (3%)
Query: 287 DRGNGFFKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAILLD 346
+RG + + G+Y A+E + + N L AM + +I ++EEA T A+ ++
Sbjct: 1275 NRGLIYVELGQYGFALEDFKQAALISRTNGSLCHATAMCHHRINEFEEAVNFFTWALKIN 1334
Query: 347 GSYSKAFARRGTARTFLG---KLNEAKQDFETVLLLEP 381
+ A+ RG + G +A++DF L + P
Sbjct: 1335 PCFLDAYVGRGNSYMEYGHDEATKQAQKDFLKALHINP 1372
Score = 34.3 bits (77), Expect = 0.36
Identities = 22/54 (40%), Positives = 27/54 (50%), Gaps = 1/54 (1%)
Query: 329 IQKYEEAEKDCTQAILLDGSYSK-AFARRGTARTFLGKLNEAKQDFETVLLLEP 381
I+ YE K T+ I Y A+ RRG LGKL A D + V+LLEP
Sbjct: 895 IKYYESEVKILTEEINDKTKYPAFAYCRRGAIYRKLGKLQSAMNDLQRVILLEP 948
Score = 34.3 bits (77), Expect = 0.36
Identities = 24/87 (27%), Positives = 37/87 (42%), Gaps = 2/87 (2%)
Query: 322 RAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLEP 381
R Y K+ K + A D + ILL+ + A+ R F K+NEA D +
Sbjct: 923 RGAIYRKLGKLQSAMNDLQRVILLEPLFLNAYWHRHLIYLFQDKINEALDDLNYIHKYNK 982
Query: 382 GNKQAVTELSKI--KKKPLKKVIIEET 406
N +A ++I KK + I+ T
Sbjct: 983 NNTEAYLSKAEIYRGKKDITLAILNYT 1009
>gi|239750633 PREDICTED: tetratricopeptide repeat domain 6 [Homo
sapiens]
Length = 1614
Score = 58.9 bits (141), Expect = 1e-08
Identities = 35/120 (29%), Positives = 59/120 (49%)
Query: 112 HESLSQESESEEDGIHVDSQKALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPT 171
H SQ S+ + D + VL + KY+EA + + +++ P+ +
Sbjct: 1489 HRQFSQASDYFSKALKFDPENEYVLMNRAITNTILKKYEEAKEDFANVIESCPFWAAVYF 1548
Query: 172 NRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELE 231
NRA Y+ LK++ +AE D N A++L + Y+ R R + +EEA DY + L+LE
Sbjct: 1549 NRAHFYYCLKQYELAEEDLNKALSLKPNDALVYNFRAKVRGKIGLIEEAMADYNQALDLE 1608
Score = 54.7 bits (130), Expect = 3e-07
Identities = 33/122 (27%), Positives = 58/122 (47%)
Query: 123 EDGIHVDSQKALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRLKK 182
+D I ++ + +L GN YF ++ +A D ++K + DP N + NRA LKK
Sbjct: 1466 QDAITLNPKYSLAYFNAGNIYFHHRQFSQASDYFSKALKFDPENEYVLMNRAITNTILKK 1525
Query: 183 FAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNFEATNELR 242
+ A+ D + + Y R + L++ E A++D + L L+PN+ N
Sbjct: 1526 YEEAKEDFANVIESCPFWAAVYFNRAHFYYCLKQYELAEEDLNKALSLKPNDALVYNFRA 1585
Query: 243 KI 244
K+
Sbjct: 1586 KV 1587
Score = 53.1 bits (126), Expect = 7e-07
Identities = 57/305 (18%), Positives = 115/305 (37%), Gaps = 50/305 (16%)
Query: 113 ESLSQESESEEDGIHVDSQKALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTN 172
E+ Q + +H++ G QGK+ +A + +T +D DP N +
Sbjct: 1355 EATKQAQKDFLKALHINPAYIKARISFGYNLQAQGKFQKAWNHFTIAIDTDPKNYLAYEG 1414
Query: 173 RASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEP 232
RA ++ A D N A+ ++ + + + RG + + A KDY+ + L P
Sbjct: 1415 RAVVCLQMGNNFAAMQDINAAMKISTT-AEFLTNRGVIHEFMGHKQNAMKDYQDAITLNP 1473
Query: 233 NNFEATNELRKISQALASKENSYPKEADIVIKSTEGERKQIEAQQNKQQAISEKDRGNGF 292
+ +++ + GN +
Sbjct: 1474 -----------------------------------------------KYSLAYFNAGNIY 1486
Query: 293 FKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAILLDGSYSKA 352
F ++ +A + +++ + D N + NRA+ ++KYEEA++D I ++
Sbjct: 1487 FHHRQFSQASDYFSKALKFDPENEYVLMNRAITNTILKKYEEAKEDFANVIESCPFWAAV 1546
Query: 353 FARRGTARTFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIKKKPLKKVIIEETGNLIQT 412
+ R L + A++D L L+P + +K++ K +I E + Q
Sbjct: 1547 YFNRAHFYYCLKQYELAEEDLNKALSLKPNDALVYNFRAKVRGK--IGLIEEAMADYNQA 1604
Query: 413 IDVPD 417
+D+ D
Sbjct: 1605 LDLED 1609
Score = 43.5 bits (101), Expect = 6e-04
Identities = 66/292 (22%), Positives = 117/292 (40%), Gaps = 61/292 (20%)
Query: 143 YFKQGKYDE------AIDCYTKGMDADPYNPVLPTNRASAYFRLKKFAVAESDCNLAVAL 196
YF++G+ E AID ++K + DP R Y + + A D + +
Sbjct: 1022 YFRRGEMYEITNKVLAIDDFSKCIFYDPKRTDALLKRGLFYCENENWFAAIEDFTALLNI 1081
Query: 197 NRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNFEATNELRKISQALASKENSYP 256
+ ++A RG ++ + AK ++ E++ + +EL + QAL S+
Sbjct: 1082 DHQNSQA---RGQYLLMMKYYDLAKFTIYQIAEMD----KGLSELSPMQQALIY---SFC 1131
Query: 257 KEADIVIKSTEG--------------ERKQIEAQQNKQ---------QAISEKDRGNG-- 291
+ D I+ +G + Q++A++ K+ AIS D+G
Sbjct: 1132 ENHDKAIEVLDGISWNRAEMTMCALLAKVQMKAKRTKEAVEVLKKALDAISHSDKGPDAT 1191
Query: 292 -------------FFKEGK----YERAIECYTRGIAADGANALLPANRAMAYLKIQKYEE 334
+ +EG Y+ AI T I+ D + + NRA+ Y KI++ +
Sbjct: 1192 AISADCLYNLGLCYMEEGNLQMTYKLAITDLTTAISMDKNSYIAFYNRALCYTKIRELQM 1251
Query: 335 AEKDCTQAILLDGSYS---KAFARRGTARTFLGKLNEAKQDFETVLLLEPGN 383
A D +LLD + + F RG LG+ A +DF+ L+ N
Sbjct: 1252 ALTDYGIVLLLDATETVKLNTFLNRGLIYVELGQYGFALEDFKQAALISRTN 1303
Score = 36.6 bits (83), Expect = 0.072
Identities = 47/174 (27%), Positives = 76/174 (43%), Gaps = 28/174 (16%)
Query: 203 AYSRRGAARFALQKLEEAKKDYERVLELEP---NNF--------------EATNELRKIS 245
AY RRGA L KL+ A D +RV+ LEP N + EA ++L I
Sbjct: 919 AYCRRGAIYRKLGKLQSAMNDLQRVILLEPLFLNAYWHRHLIYLFQDKINEALDDLNYIH 978
Query: 246 QALASKENSYPKEADIVIKSTEGERKQIEAQQNKQQAI-SEKDRGNGFFKEGK-YE---- 299
+ + +Y +A+I G++ A N QAI S + +F+ G+ YE
Sbjct: 979 KYNKNNTEAYLSKAEIY----RGKKDITLAILNYTQAIKSTPTDADIYFRRGEMYEITNK 1034
Query: 300 -RAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAILLDGSYSKA 352
AI+ +++ I D R + Y + + + A +D T + +D S+A
Sbjct: 1035 VLAIDDFSKCIFYDPKRTDALLKRGLFYCENENWFAAIEDFTALLNIDHQNSQA 1088
Score = 34.7 bits (78), Expect = 0.27
Identities = 25/98 (25%), Positives = 46/98 (46%), Gaps = 3/98 (3%)
Query: 287 DRGNGFFKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAILLD 346
+RG + + G+Y A+E + + N L AM + +I ++EEA T A+ ++
Sbjct: 1275 NRGLIYVELGQYGFALEDFKQAALISRTNGSLCHATAMCHHRINEFEEAVNFFTWALKIN 1334
Query: 347 GSYSKAFARRGTARTFLG---KLNEAKQDFETVLLLEP 381
+ A+ RG + G +A++DF L + P
Sbjct: 1335 PCFLDAYVGRGNSYMEYGHDEATKQAQKDFLKALHINP 1372
Score = 34.3 bits (77), Expect = 0.36
Identities = 22/54 (40%), Positives = 27/54 (50%), Gaps = 1/54 (1%)
Query: 329 IQKYEEAEKDCTQAILLDGSYSK-AFARRGTARTFLGKLNEAKQDFETVLLLEP 381
I+ YE K T+ I Y A+ RRG LGKL A D + V+LLEP
Sbjct: 895 IKYYESEVKILTEEINDKTKYPAFAYCRRGAIYRKLGKLQSAMNDLQRVILLEP 948
Score = 34.3 bits (77), Expect = 0.36
Identities = 24/87 (27%), Positives = 37/87 (42%), Gaps = 2/87 (2%)
Query: 322 RAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLEP 381
R Y K+ K + A D + ILL+ + A+ R F K+NEA D +
Sbjct: 923 RGAIYRKLGKLQSAMNDLQRVILLEPLFLNAYWHRHLIYLFQDKINEALDDLNYIHKYNK 982
Query: 382 GNKQAVTELSKI--KKKPLKKVIIEET 406
N +A ++I KK + I+ T
Sbjct: 983 NNTEAYLSKAEIYRGKKDITLAILNYT 1009
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.129 0.350
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,047,836
Number of Sequences: 37866
Number of extensions: 985276
Number of successful extensions: 5377
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 97
Number of HSP's successfully gapped in prelim test: 275
Number of HSP's that attempted gapping in prelim test: 4500
Number of HSP's gapped (non-prelim): 976
length of query: 631
length of database: 18,247,518
effective HSP length: 108
effective length of query: 523
effective length of database: 14,157,990
effective search space: 7404628770
effective search space used: 7404628770
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.