Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 225543215
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|225543215 antigen identified by monoclonal antibody Ki-67
isoform 2 [Homo sapiens]
(2896 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|225543215 antigen identified by monoclonal antibody Ki-67 iso... 5749 0.0
gi|103472005 antigen identified by monoclonal antibody Ki-67 iso... 5481 0.0
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 98 1e-19
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 98 1e-19
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 94 3e-18
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 94 3e-18
gi|238624188 diffuse panbronchiolitis critical region 1 protein ... 86 7e-16
gi|239740773 PREDICTED: similar to diffuse panbronchiolitis crit... 83 3e-15
gi|91982772 mucin 17 [Homo sapiens] 78 1e-13
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 75 7e-13
gi|150170670 piccolo isoform 2 [Homo sapiens] 75 7e-13
gi|150378539 piccolo isoform 1 [Homo sapiens] 75 7e-13
gi|16554449 zonadhesin isoform 3 [Homo sapiens] 69 5e-11
gi|27881494 zonadhesin isoform 6 [Homo sapiens] 69 5e-11
gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d... 66 6e-10
gi|52426735 ankyrin 2 isoform 1 [Homo sapiens] 65 7e-10
gi|153945728 microtubule-associated protein 1B [Homo sapiens] 65 1e-09
gi|110349719 titin isoform N2-A [Homo sapiens] 64 2e-09
gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapi... 63 5e-09
gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f... 62 8e-09
gi|14790190 spen homolog, transcriptional regulator [Homo sapiens] 62 1e-08
gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b ... 62 1e-08
gi|239743293 PREDICTED: mucin 12 [Homo sapiens] 61 2e-08
gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e... 60 3e-08
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 59 5e-08
gi|154146223 splicing factor, arginine/serine-rich 130 [Homo sap... 57 2e-07
gi|154146193 splicing factor, arginine/serine-rich 130 [Homo sap... 57 2e-07
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 57 3e-07
gi|102467242 inner centromere protein antigens 135/155kDa isofor... 56 5e-07
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa... 55 1e-06
>gi|225543215 antigen identified by monoclonal antibody Ki-67 isoform
2 [Homo sapiens]
Length = 2896
Score = 5749 bits (14914), Expect = 0.0
Identities = 2896/2896 (100%), Positives = 2896/2896 (100%)
Query: 1 MWPTRRLVTIKRSGVDGPHFPLSLSTCLFGRGIECDIRIQLPVVSKQHCKIEIHEQEAIL 60
MWPTRRLVTIKRSGVDGPHFPLSLSTCLFGRGIECDIRIQLPVVSKQHCKIEIHEQEAIL
Sbjct: 1 MWPTRRLVTIKRSGVDGPHFPLSLSTCLFGRGIECDIRIQLPVVSKQHCKIEIHEQEAIL 60
Query: 61 HNFSSTNPTQVNGSVIDEPVRLKHGDVITIIDRSFRYENESLQNGRKSTEFPRKIREQEP 120
HNFSSTNPTQVNGSVIDEPVRLKHGDVITIIDRSFRYENESLQNGRKSTEFPRKIREQEP
Sbjct: 61 HNFSSTNPTQVNGSVIDEPVRLKHGDVITIIDRSFRYENESLQNGRKSTEFPRKIREQEP 120
Query: 121 ARRVSRSSFSSDPDESEGIPLKRRRVSFGGHLRPELFDENLPPNTPLKRGEAPTKRKSLV 180
ARRVSRSSFSSDPDESEGIPLKRRRVSFGGHLRPELFDENLPPNTPLKRGEAPTKRKSLV
Sbjct: 121 ARRVSRSSFSSDPDESEGIPLKRRRVSFGGHLRPELFDENLPPNTPLKRGEAPTKRKSLV 180
Query: 181 MHTPPVLKKIIKEQPQPSGKQESGSEIHVEVKAQSLVISPPAPSPRKTPVASDQRRRSCK 240
MHTPPVLKKIIKEQPQPSGKQESGSEIHVEVKAQSLVISPPAPSPRKTPVASDQRRRSCK
Sbjct: 181 MHTPPVLKKIIKEQPQPSGKQESGSEIHVEVKAQSLVISPPAPSPRKTPVASDQRRRSCK 240
Query: 241 TAPASSSKSQTEVPKRGGRKSGNLPSKRVSISRSQHDILQMICSKRRSGASEANLIVAKS 300
TAPASSSKSQTEVPKRGGRKSGNLPSKRVSISRSQHDILQMICSKRRSGASEANLIVAKS
Sbjct: 241 TAPASSSKSQTEVPKRGGRKSGNLPSKRVSISRSQHDILQMICSKRRSGASEANLIVAKS 300
Query: 301 WADVVKLGAKQTQTKVIKHGPQRSMNKRQRRPATPKKPVGEVHSQFSTGHANSPCTIIIG 360
WADVVKLGAKQTQTKVIKHGPQRSMNKRQRRPATPKKPVGEVHSQFSTGHANSPCTIIIG
Sbjct: 301 WADVVKLGAKQTQTKVIKHGPQRSMNKRQRRPATPKKPVGEVHSQFSTGHANSPCTIIIG 360
Query: 361 KAHTEKVHVPARPYRVLNNFISNQKMDFKEDLSGIAEMFKTPVKEQPQLTSTCHIAISNS 420
KAHTEKVHVPARPYRVLNNFISNQKMDFKEDLSGIAEMFKTPVKEQPQLTSTCHIAISNS
Sbjct: 361 KAHTEKVHVPARPYRVLNNFISNQKMDFKEDLSGIAEMFKTPVKEQPQLTSTCHIAISNS 420
Query: 421 ENLLGKQFQGTDSGEEPLLPTSESFGGNVFFSAQNAAKQPSDKCSASPPLRRQCIRENGN 480
ENLLGKQFQGTDSGEEPLLPTSESFGGNVFFSAQNAAKQPSDKCSASPPLRRQCIRENGN
Sbjct: 421 ENLLGKQFQGTDSGEEPLLPTSESFGGNVFFSAQNAAKQPSDKCSASPPLRRQCIRENGN 480
Query: 481 VAKTPRNTYKMTSLETKTSDTETEPSKTVSTANRSGRSTEFRNIQKLPVESKSEETNTEI 540
VAKTPRNTYKMTSLETKTSDTETEPSKTVSTANRSGRSTEFRNIQKLPVESKSEETNTEI
Sbjct: 481 VAKTPRNTYKMTSLETKTSDTETEPSKTVSTANRSGRSTEFRNIQKLPVESKSEETNTEI 540
Query: 541 VECILKRGQKATLLQQRREGEMKEIERPFETYKENIELKENDEKMKAMKRSRTWGQKCAP 600
VECILKRGQKATLLQQRREGEMKEIERPFETYKENIELKENDEKMKAMKRSRTWGQKCAP
Sbjct: 541 VECILKRGQKATLLQQRREGEMKEIERPFETYKENIELKENDEKMKAMKRSRTWGQKCAP 600
Query: 601 MSDLTDLKSLPDTELMKDTARGQNLLQTQDHAKAPKSEKGKITKMPCQSLQPEPINTPTH 660
MSDLTDLKSLPDTELMKDTARGQNLLQTQDHAKAPKSEKGKITKMPCQSLQPEPINTPTH
Sbjct: 601 MSDLTDLKSLPDTELMKDTARGQNLLQTQDHAKAPKSEKGKITKMPCQSLQPEPINTPTH 660
Query: 661 TKQQLKASLGKVGVKEELLAVGKFTRTSGETTHTHREPAGDGKSIRTFKESPKQILDPAA 720
TKQQLKASLGKVGVKEELLAVGKFTRTSGETTHTHREPAGDGKSIRTFKESPKQILDPAA
Sbjct: 661 TKQQLKASLGKVGVKEELLAVGKFTRTSGETTHTHREPAGDGKSIRTFKESPKQILDPAA 720
Query: 721 RVTGMKKWPRTPKEEAQSLEDLAGFKELFQTPGPSEESMTDEKTTKIACKSPPPESVDTP 780
RVTGMKKWPRTPKEEAQSLEDLAGFKELFQTPGPSEESMTDEKTTKIACKSPPPESVDTP
Sbjct: 721 RVTGMKKWPRTPKEEAQSLEDLAGFKELFQTPGPSEESMTDEKTTKIACKSPPPESVDTP 780
Query: 781 TSTKQWPKRSLRKADVEEEFLALRKLTPSAGKAMLTPKPAGGDEKDIKAFMGTPVQKLDL 840
TSTKQWPKRSLRKADVEEEFLALRKLTPSAGKAMLTPKPAGGDEKDIKAFMGTPVQKLDL
Sbjct: 781 TSTKQWPKRSLRKADVEEEFLALRKLTPSAGKAMLTPKPAGGDEKDIKAFMGTPVQKLDL 840
Query: 841 AGTLPGSKRQLQTPKEKAQALEDLAGFKELFQTPGHTEELVAAGKTTKIPCDSPQSDPVD 900
AGTLPGSKRQLQTPKEKAQALEDLAGFKELFQTPGHTEELVAAGKTTKIPCDSPQSDPVD
Sbjct: 841 AGTLPGSKRQLQTPKEKAQALEDLAGFKELFQTPGHTEELVAAGKTTKIPCDSPQSDPVD 900
Query: 901 TPTSTKQRPKRSIRKADVEGELLACRNLMPSAGKAMHTPKPSVGEEKDIIIFVGTPVQKL 960
TPTSTKQRPKRSIRKADVEGELLACRNLMPSAGKAMHTPKPSVGEEKDIIIFVGTPVQKL
Sbjct: 901 TPTSTKQRPKRSIRKADVEGELLACRNLMPSAGKAMHTPKPSVGEEKDIIIFVGTPVQKL 960
Query: 961 DLTENLTGSKRRPQTPKEEAQALEDLTGFKELFQTPGHTEEAVAAGKTTKMPCESSPPES 1020
DLTENLTGSKRRPQTPKEEAQALEDLTGFKELFQTPGHTEEAVAAGKTTKMPCESSPPES
Sbjct: 961 DLTENLTGSKRRPQTPKEEAQALEDLTGFKELFQTPGHTEEAVAAGKTTKMPCESSPPES 1020
Query: 1021 ADTPTSTRRQPKTPLEKRDVQKELSALKKLTQTSGETTHTDKVPGGEDKSINAFRETAKQ 1080
ADTPTSTRRQPKTPLEKRDVQKELSALKKLTQTSGETTHTDKVPGGEDKSINAFRETAKQ
Sbjct: 1021 ADTPTSTRRQPKTPLEKRDVQKELSALKKLTQTSGETTHTDKVPGGEDKSINAFRETAKQ 1080
Query: 1081 KLDPAASVTGSKRHPKTKEKAQPLEDLAGLKELFQTPVCTDKPTTHEKTTKIACRSQPDP 1140
KLDPAASVTGSKRHPKTKEKAQPLEDLAGLKELFQTPVCTDKPTTHEKTTKIACRSQPDP
Sbjct: 1081 KLDPAASVTGSKRHPKTKEKAQPLEDLAGLKELFQTPVCTDKPTTHEKTTKIACRSQPDP 1140
Query: 1141 VDTPTSSKPQSKRSLRKVDVEEEFFALRKRTPSAGKAMHTPKPAVSGEKNIYAFMGTPVQ 1200
VDTPTSSKPQSKRSLRKVDVEEEFFALRKRTPSAGKAMHTPKPAVSGEKNIYAFMGTPVQ
Sbjct: 1141 VDTPTSSKPQSKRSLRKVDVEEEFFALRKRTPSAGKAMHTPKPAVSGEKNIYAFMGTPVQ 1200
Query: 1201 KLDLTENLTGSKRRLQTPKEKAQALEDLAGFKELFQTRGHTEESMTNDKTAKVACKSSQP 1260
KLDLTENLTGSKRRLQTPKEKAQALEDLAGFKELFQTRGHTEESMTNDKTAKVACKSSQP
Sbjct: 1201 KLDLTENLTGSKRRLQTPKEKAQALEDLAGFKELFQTRGHTEESMTNDKTAKVACKSSQP 1260
Query: 1261 DPDKNPASSKRRLKTSLGKVGVKEELLAVGKLTQTSGETTHTHTEPTGDGKSMKAFMESP 1320
DPDKNPASSKRRLKTSLGKVGVKEELLAVGKLTQTSGETTHTHTEPTGDGKSMKAFMESP
Sbjct: 1261 DPDKNPASSKRRLKTSLGKVGVKEELLAVGKLTQTSGETTHTHTEPTGDGKSMKAFMESP 1320
Query: 1321 KQILDSAASLTGSKRQLRTPKGKSEVPEDLAGFIELFQTPSHTKESMTNEKTTKVSYRAS 1380
KQILDSAASLTGSKRQLRTPKGKSEVPEDLAGFIELFQTPSHTKESMTNEKTTKVSYRAS
Sbjct: 1321 KQILDSAASLTGSKRQLRTPKGKSEVPEDLAGFIELFQTPSHTKESMTNEKTTKVSYRAS 1380
Query: 1381 QPDLVDTPTSSKPQPKRSLRKADTEEEFLAFRKQTPSAGKAMHTPKPAVGEEKDINTFLG 1440
QPDLVDTPTSSKPQPKRSLRKADTEEEFLAFRKQTPSAGKAMHTPKPAVGEEKDINTFLG
Sbjct: 1381 QPDLVDTPTSSKPQPKRSLRKADTEEEFLAFRKQTPSAGKAMHTPKPAVGEEKDINTFLG 1440
Query: 1441 TPVQKLDQPGNLPGSNRRLQTRKEKAQALEELTGFRELFQTPCTDNPTTDEKTTKKILCK 1500
TPVQKLDQPGNLPGSNRRLQTRKEKAQALEELTGFRELFQTPCTDNPTTDEKTTKKILCK
Sbjct: 1441 TPVQKLDQPGNLPGSNRRLQTRKEKAQALEELTGFRELFQTPCTDNPTTDEKTTKKILCK 1500
Query: 1501 SPQSDPADTPTNTKQRPKRSLKKADVEEEFLAFRKLTPSAGKAMHTPKAAVGEEKDINTF 1560
SPQSDPADTPTNTKQRPKRSLKKADVEEEFLAFRKLTPSAGKAMHTPKAAVGEEKDINTF
Sbjct: 1501 SPQSDPADTPTNTKQRPKRSLKKADVEEEFLAFRKLTPSAGKAMHTPKAAVGEEKDINTF 1560
Query: 1561 VGTPVEKLDLLGNLPGSKRRPQTPKEKAKALEDLAGFKELFQTPGHTEESMTDDKITEVS 1620
VGTPVEKLDLLGNLPGSKRRPQTPKEKAKALEDLAGFKELFQTPGHTEESMTDDKITEVS
Sbjct: 1561 VGTPVEKLDLLGNLPGSKRRPQTPKEKAKALEDLAGFKELFQTPGHTEESMTDDKITEVS 1620
Query: 1621 CKSPQPDPVKTPTSSKQRLKISLGKVGVKEEVLPVGKLTQTSGKTTQTHRETAGDGKSIK 1680
CKSPQPDPVKTPTSSKQRLKISLGKVGVKEEVLPVGKLTQTSGKTTQTHRETAGDGKSIK
Sbjct: 1621 CKSPQPDPVKTPTSSKQRLKISLGKVGVKEEVLPVGKLTQTSGKTTQTHRETAGDGKSIK 1680
Query: 1681 AFKESAKQMLDPANYGTGMERWPRTPKEEAQSLEDLAGFKELFQTPDHTEESTTDDKTTK 1740
AFKESAKQMLDPANYGTGMERWPRTPKEEAQSLEDLAGFKELFQTPDHTEESTTDDKTTK
Sbjct: 1681 AFKESAKQMLDPANYGTGMERWPRTPKEEAQSLEDLAGFKELFQTPDHTEESTTDDKTTK 1740
Query: 1741 IACKSPPPESMDTPTSTRRRPKTPLGKRDIVEELSALKQLTQTTHTDKVPGDEDKGINVF 1800
IACKSPPPESMDTPTSTRRRPKTPLGKRDIVEELSALKQLTQTTHTDKVPGDEDKGINVF
Sbjct: 1741 IACKSPPPESMDTPTSTRRRPKTPLGKRDIVEELSALKQLTQTTHTDKVPGDEDKGINVF 1800
Query: 1801 RETAKQKLDPAASVTGSKRQPRTPKGKAQPLEDLAGLKELFQTPICTDKPTTHEKTTKIA 1860
RETAKQKLDPAASVTGSKRQPRTPKGKAQPLEDLAGLKELFQTPICTDKPTTHEKTTKIA
Sbjct: 1801 RETAKQKLDPAASVTGSKRQPRTPKGKAQPLEDLAGLKELFQTPICTDKPTTHEKTTKIA 1860
Query: 1861 CRSPQPDPVGTPTIFKPQSKRSLRKADVEEESLALRKRTPSVGKAMDTPKPAGGDEKDMK 1920
CRSPQPDPVGTPTIFKPQSKRSLRKADVEEESLALRKRTPSVGKAMDTPKPAGGDEKDMK
Sbjct: 1861 CRSPQPDPVGTPTIFKPQSKRSLRKADVEEESLALRKRTPSVGKAMDTPKPAGGDEKDMK 1920
Query: 1921 AFMGTPVQKLDLPGNLPGSKRWPQTPKEKAQALEDLAGFKELFQTPGTDKPTTDEKTTKI 1980
AFMGTPVQKLDLPGNLPGSKRWPQTPKEKAQALEDLAGFKELFQTPGTDKPTTDEKTTKI
Sbjct: 1921 AFMGTPVQKLDLPGNLPGSKRWPQTPKEKAQALEDLAGFKELFQTPGTDKPTTDEKTTKI 1980
Query: 1981 ACKSPQPDPVDTPASTKQRPKRNLRKADVEEEFLALRKRTPSAGKAMDTPKPAVSDEKNI 2040
ACKSPQPDPVDTPASTKQRPKRNLRKADVEEEFLALRKRTPSAGKAMDTPKPAVSDEKNI
Sbjct: 1981 ACKSPQPDPVDTPASTKQRPKRNLRKADVEEEFLALRKRTPSAGKAMDTPKPAVSDEKNI 2040
Query: 2041 NTFVETPVQKLDLLGNLPGSKRQPQTPKEKAEALEDLVGFKELFQTPGHTEESMTDDKIT 2100
NTFVETPVQKLDLLGNLPGSKRQPQTPKEKAEALEDLVGFKELFQTPGHTEESMTDDKIT
Sbjct: 2041 NTFVETPVQKLDLLGNLPGSKRQPQTPKEKAEALEDLVGFKELFQTPGHTEESMTDDKIT 2100
Query: 2101 EVSCKSPQPESFKTSRSSKQRLKIPLVKVDMKEEPLAVSKLTRTSGETTQTHTEPTGDSK 2160
EVSCKSPQPESFKTSRSSKQRLKIPLVKVDMKEEPLAVSKLTRTSGETTQTHTEPTGDSK
Sbjct: 2101 EVSCKSPQPESFKTSRSSKQRLKIPLVKVDMKEEPLAVSKLTRTSGETTQTHTEPTGDSK 2160
Query: 2161 SIKAFKESPKQILDPAASVTGSRRQLRTRKEKARALEDLVDFKELFSAPGHTEESMTIDK 2220
SIKAFKESPKQILDPAASVTGSRRQLRTRKEKARALEDLVDFKELFSAPGHTEESMTIDK
Sbjct: 2161 SIKAFKESPKQILDPAASVTGSRRQLRTRKEKARALEDLVDFKELFSAPGHTEESMTIDK 2220
Query: 2221 NTKIPCKSPPPELTDTATSTKRCPKTRPRKEVKEELSAVERLTQTSGQSTHTHKEPASGD 2280
NTKIPCKSPPPELTDTATSTKRCPKTRPRKEVKEELSAVERLTQTSGQSTHTHKEPASGD
Sbjct: 2221 NTKIPCKSPPPELTDTATSTKRCPKTRPRKEVKEELSAVERLTQTSGQSTHTHKEPASGD 2280
Query: 2281 EGIKVLKQRAKKKPNPVEEEPSRRRPRAPKEKAQPLEDLAGFTELSETSGHTQESLTAGK 2340
EGIKVLKQRAKKKPNPVEEEPSRRRPRAPKEKAQPLEDLAGFTELSETSGHTQESLTAGK
Sbjct: 2281 EGIKVLKQRAKKKPNPVEEEPSRRRPRAPKEKAQPLEDLAGFTELSETSGHTQESLTAGK 2340
Query: 2341 ATKIPCESPPLEVVDTTASTKRHLRTRVQKVQVKEEPSAVKFTQTSGETTDADKEPAGED 2400
ATKIPCESPPLEVVDTTASTKRHLRTRVQKVQVKEEPSAVKFTQTSGETTDADKEPAGED
Sbjct: 2341 ATKIPCESPPLEVVDTTASTKRHLRTRVQKVQVKEEPSAVKFTQTSGETTDADKEPAGED 2400
Query: 2401 KGIKALKESAKQTPAPAASVTGSRRRPRAPRESAQAIEDLAGFKDPAAGHTEESMTDDKT 2460
KGIKALKESAKQTPAPAASVTGSRRRPRAPRESAQAIEDLAGFKDPAAGHTEESMTDDKT
Sbjct: 2401 KGIKALKESAKQTPAPAASVTGSRRRPRAPRESAQAIEDLAGFKDPAAGHTEESMTDDKT 2460
Query: 2461 TKIPCKSSPELEDTATSSKRRPRTRAQKVEVKEELLAVGKLTQTSGETTHTDKEPVGEGK 2520
TKIPCKSSPELEDTATSSKRRPRTRAQKVEVKEELLAVGKLTQTSGETTHTDKEPVGEGK
Sbjct: 2461 TKIPCKSSPELEDTATSSKRRPRTRAQKVEVKEELLAVGKLTQTSGETTHTDKEPVGEGK 2520
Query: 2521 GTKAFKQPAKRKLDAEDVIGSRRQPRAPKEKAQPLEDLASFQELSQTPGHTEELANGAAD 2580
GTKAFKQPAKRKLDAEDVIGSRRQPRAPKEKAQPLEDLASFQELSQTPGHTEELANGAAD
Sbjct: 2521 GTKAFKQPAKRKLDAEDVIGSRRQPRAPKEKAQPLEDLASFQELSQTPGHTEELANGAAD 2580
Query: 2581 SFTSAPKQTPDSGKPLKISRRVLRAPKVEPVGDVVSTRDPVKSQSKSNTSLPPLPFKRGG 2640
SFTSAPKQTPDSGKPLKISRRVLRAPKVEPVGDVVSTRDPVKSQSKSNTSLPPLPFKRGG
Sbjct: 2581 SFTSAPKQTPDSGKPLKISRRVLRAPKVEPVGDVVSTRDPVKSQSKSNTSLPPLPFKRGG 2640
Query: 2641 GKDGSVTGTKRLRCMPAPEEIVEELPASKKQRVAPRARGKSSEPVVIMKRSLRTSAKRIE 2700
GKDGSVTGTKRLRCMPAPEEIVEELPASKKQRVAPRARGKSSEPVVIMKRSLRTSAKRIE
Sbjct: 2641 GKDGSVTGTKRLRCMPAPEEIVEELPASKKQRVAPRARGKSSEPVVIMKRSLRTSAKRIE 2700
Query: 2701 PAEELNSNDMKTNKEEHKLQDSVPENKGISLRSRRQNKTEAEQQITEVFVLAERIEINRN 2760
PAEELNSNDMKTNKEEHKLQDSVPENKGISLRSRRQNKTEAEQQITEVFVLAERIEINRN
Sbjct: 2701 PAEELNSNDMKTNKEEHKLQDSVPENKGISLRSRRQNKTEAEQQITEVFVLAERIEINRN 2760
Query: 2761 EKKPMKTSPEMDIQNPDDGARKPIPRDKVTENKRCLRSARQNESSQPKVAEESGGQKSAK 2820
EKKPMKTSPEMDIQNPDDGARKPIPRDKVTENKRCLRSARQNESSQPKVAEESGGQKSAK
Sbjct: 2761 EKKPMKTSPEMDIQNPDDGARKPIPRDKVTENKRCLRSARQNESSQPKVAEESGGQKSAK 2820
Query: 2821 VLMQNQKGKGEAGNSDSMCLRSRKTKSQPAASTLESKSVQRVTRSVKRCAENPKKAEDNV 2880
VLMQNQKGKGEAGNSDSMCLRSRKTKSQPAASTLESKSVQRVTRSVKRCAENPKKAEDNV
Sbjct: 2821 VLMQNQKGKGEAGNSDSMCLRSRKTKSQPAASTLESKSVQRVTRSVKRCAENPKKAEDNV 2880
Query: 2881 CVKKIRTRSHRDSEDI 2896
CVKKIRTRSHRDSEDI
Sbjct: 2881 CVKKIRTRSHRDSEDI 2896
>gi|103472005 antigen identified by monoclonal antibody Ki-67 isoform
1 [Homo sapiens]
Length = 3256
Score = 5481 bits (14219), Expect = 0.0
Identities = 2764/2773 (99%), Positives = 2767/2773 (99%)
Query: 124 VSRSSFSSDPDESEGIPLKRRRVSFGGHLRPELFDENLPPNTPLKRGEAPTKRKSLVMHT 183
V ++F +ESEGIPLKRRRVSFGGHLRPELFDENLPPNTPLKRGEAPTKRKSLVMHT
Sbjct: 484 VDINNFGDSINESEGIPLKRRRVSFGGHLRPELFDENLPPNTPLKRGEAPTKRKSLVMHT 543
Query: 184 PPVLKKIIKEQPQPSGKQESGSEIHVEVKAQSLVISPPAPSPRKTPVASDQRRRSCKTAP 243
PPVLKKIIKEQPQPSGKQESGSEIHVEVKAQSLVISPPAPSPRKTPVASDQRRRSCKTAP
Sbjct: 544 PPVLKKIIKEQPQPSGKQESGSEIHVEVKAQSLVISPPAPSPRKTPVASDQRRRSCKTAP 603
Query: 244 ASSSKSQTEVPKRGGRKSGNLPSKRVSISRSQHDILQMICSKRRSGASEANLIVAKSWAD 303
ASSSKSQTEVPKRGGRKSGNLPSKRVSISRSQHDILQMICSKRRSGASEANLIVAKSWAD
Sbjct: 604 ASSSKSQTEVPKRGGRKSGNLPSKRVSISRSQHDILQMICSKRRSGASEANLIVAKSWAD 663
Query: 304 VVKLGAKQTQTKVIKHGPQRSMNKRQRRPATPKKPVGEVHSQFSTGHANSPCTIIIGKAH 363
VVKLGAKQTQTKVIKHGPQRSMNKRQRRPATPKKPVGEVHSQFSTGHANSPCTIIIGKAH
Sbjct: 664 VVKLGAKQTQTKVIKHGPQRSMNKRQRRPATPKKPVGEVHSQFSTGHANSPCTIIIGKAH 723
Query: 364 TEKVHVPARPYRVLNNFISNQKMDFKEDLSGIAEMFKTPVKEQPQLTSTCHIAISNSENL 423
TEKVHVPARPYRVLNNFISNQKMDFKEDLSGIAEMFKTPVKEQPQLTSTCHIAISNSENL
Sbjct: 724 TEKVHVPARPYRVLNNFISNQKMDFKEDLSGIAEMFKTPVKEQPQLTSTCHIAISNSENL 783
Query: 424 LGKQFQGTDSGEEPLLPTSESFGGNVFFSAQNAAKQPSDKCSASPPLRRQCIRENGNVAK 483
LGKQFQGTDSGEEPLLPTSESFGGNVFFSAQNAAKQPSDKCSASPPLRRQCIRENGNVAK
Sbjct: 784 LGKQFQGTDSGEEPLLPTSESFGGNVFFSAQNAAKQPSDKCSASPPLRRQCIRENGNVAK 843
Query: 484 TPRNTYKMTSLETKTSDTETEPSKTVSTANRSGRSTEFRNIQKLPVESKSEETNTEIVEC 543
TPRNTYKMTSLETKTSDTETEPSKTVSTANRSGRSTEFRNIQKLPVESKSEETNTEIVEC
Sbjct: 844 TPRNTYKMTSLETKTSDTETEPSKTVSTANRSGRSTEFRNIQKLPVESKSEETNTEIVEC 903
Query: 544 ILKRGQKATLLQQRREGEMKEIERPFETYKENIELKENDEKMKAMKRSRTWGQKCAPMSD 603
ILKRGQKATLLQQRREGEMKEIERPFETYKENIELKENDEKMKAMKRSRTWGQKCAPMSD
Sbjct: 904 ILKRGQKATLLQQRREGEMKEIERPFETYKENIELKENDEKMKAMKRSRTWGQKCAPMSD 963
Query: 604 LTDLKSLPDTELMKDTARGQNLLQTQDHAKAPKSEKGKITKMPCQSLQPEPINTPTHTKQ 663
LTDLKSLPDTELMKDTARGQNLLQTQDHAKAPKSEKGKITKMPCQSLQPEPINTPTHTKQ
Sbjct: 964 LTDLKSLPDTELMKDTARGQNLLQTQDHAKAPKSEKGKITKMPCQSLQPEPINTPTHTKQ 1023
Query: 664 QLKASLGKVGVKEELLAVGKFTRTSGETTHTHREPAGDGKSIRTFKESPKQILDPAARVT 723
QLKASLGKVGVKEELLAVGKFTRTSGETTHTHREPAGDGKSIRTFKESPKQILDPAARVT
Sbjct: 1024 QLKASLGKVGVKEELLAVGKFTRTSGETTHTHREPAGDGKSIRTFKESPKQILDPAARVT 1083
Query: 724 GMKKWPRTPKEEAQSLEDLAGFKELFQTPGPSEESMTDEKTTKIACKSPPPESVDTPTST 783
GMKKWPRTPKEEAQSLEDLAGFKELFQTPGPSEESMTDEKTTKIACKSPPPESVDTPTST
Sbjct: 1084 GMKKWPRTPKEEAQSLEDLAGFKELFQTPGPSEESMTDEKTTKIACKSPPPESVDTPTST 1143
Query: 784 KQWPKRSLRKADVEEEFLALRKLTPSAGKAMLTPKPAGGDEKDIKAFMGTPVQKLDLAGT 843
KQWPKRSLRKADVEEEFLALRKLTPSAGKAMLTPKPAGGDEKDIKAFMGTPVQKLDLAGT
Sbjct: 1144 KQWPKRSLRKADVEEEFLALRKLTPSAGKAMLTPKPAGGDEKDIKAFMGTPVQKLDLAGT 1203
Query: 844 LPGSKRQLQTPKEKAQALEDLAGFKELFQTPGHTEELVAAGKTTKIPCDSPQSDPVDTPT 903
LPGSKRQLQTPKEKAQALEDLAGFKELFQTPGHTEELVAAGKTTKIPCDSPQSDPVDTPT
Sbjct: 1204 LPGSKRQLQTPKEKAQALEDLAGFKELFQTPGHTEELVAAGKTTKIPCDSPQSDPVDTPT 1263
Query: 904 STKQRPKRSIRKADVEGELLACRNLMPSAGKAMHTPKPSVGEEKDIIIFVGTPVQKLDLT 963
STKQRPKRSIRKADVEGELLACRNLMPSAGKAMHTPKPSVGEEKDIIIFVGTPVQKLDLT
Sbjct: 1264 STKQRPKRSIRKADVEGELLACRNLMPSAGKAMHTPKPSVGEEKDIIIFVGTPVQKLDLT 1323
Query: 964 ENLTGSKRRPQTPKEEAQALEDLTGFKELFQTPGHTEEAVAAGKTTKMPCESSPPESADT 1023
ENLTGSKRRPQTPKEEAQALEDLTGFKELFQTPGHTEEAVAAGKTTKMPCESSPPESADT
Sbjct: 1324 ENLTGSKRRPQTPKEEAQALEDLTGFKELFQTPGHTEEAVAAGKTTKMPCESSPPESADT 1383
Query: 1024 PTSTRRQPKTPLEKRDVQKELSALKKLTQTSGETTHTDKVPGGEDKSINAFRETAKQKLD 1083
PTSTRRQPKTPLEKRDVQKELSALKKLTQTSGETTHTDKVPGGEDKSINAFRETAKQKLD
Sbjct: 1384 PTSTRRQPKTPLEKRDVQKELSALKKLTQTSGETTHTDKVPGGEDKSINAFRETAKQKLD 1443
Query: 1084 PAASVTGSKRHPKTKEKAQPLEDLAGLKELFQTPVCTDKPTTHEKTTKIACRSQPDPVDT 1143
PAASVTGSKRHPKTKEKAQPLEDLAGLKELFQTPVCTDKPTTHEKTTKIACRSQPDPVDT
Sbjct: 1444 PAASVTGSKRHPKTKEKAQPLEDLAGLKELFQTPVCTDKPTTHEKTTKIACRSQPDPVDT 1503
Query: 1144 PTSSKPQSKRSLRKVDVEEEFFALRKRTPSAGKAMHTPKPAVSGEKNIYAFMGTPVQKLD 1203
PTSSKPQSKRSLRKVDVEEEFFALRKRTPSAGKAMHTPKPAVSGEKNIYAFMGTPVQKLD
Sbjct: 1504 PTSSKPQSKRSLRKVDVEEEFFALRKRTPSAGKAMHTPKPAVSGEKNIYAFMGTPVQKLD 1563
Query: 1204 LTENLTGSKRRLQTPKEKAQALEDLAGFKELFQTRGHTEESMTNDKTAKVACKSSQPDPD 1263
LTENLTGSKRRLQTPKEKAQALEDLAGFKELFQTRGHTEESMTNDKTAKVACKSSQPDPD
Sbjct: 1564 LTENLTGSKRRLQTPKEKAQALEDLAGFKELFQTRGHTEESMTNDKTAKVACKSSQPDPD 1623
Query: 1264 KNPASSKRRLKTSLGKVGVKEELLAVGKLTQTSGETTHTHTEPTGDGKSMKAFMESPKQI 1323
KNPASSKRRLKTSLGKVGVKEELLAVGKLTQTSGETTHTHTEPTGDGKSMKAFMESPKQI
Sbjct: 1624 KNPASSKRRLKTSLGKVGVKEELLAVGKLTQTSGETTHTHTEPTGDGKSMKAFMESPKQI 1683
Query: 1324 LDSAASLTGSKRQLRTPKGKSEVPEDLAGFIELFQTPSHTKESMTNEKTTKVSYRASQPD 1383
LDSAASLTGSKRQLRTPKGKSEVPEDLAGFIELFQTPSHTKESMTNEKTTKVSYRASQPD
Sbjct: 1684 LDSAASLTGSKRQLRTPKGKSEVPEDLAGFIELFQTPSHTKESMTNEKTTKVSYRASQPD 1743
Query: 1384 LVDTPTSSKPQPKRSLRKADTEEEFLAFRKQTPSAGKAMHTPKPAVGEEKDINTFLGTPV 1443
LVDTPTSSKPQPKRSLRKADTEEEFLAFRKQTPSAGKAMHTPKPAVGEEKDINTFLGTPV
Sbjct: 1744 LVDTPTSSKPQPKRSLRKADTEEEFLAFRKQTPSAGKAMHTPKPAVGEEKDINTFLGTPV 1803
Query: 1444 QKLDQPGNLPGSNRRLQTRKEKAQALEELTGFRELFQTPCTDNPTTDEKTTKKILCKSPQ 1503
QKLDQPGNLPGSNRRLQTRKEKAQALEELTGFRELFQTPCTDNPTTDEKTTKKILCKSPQ
Sbjct: 1804 QKLDQPGNLPGSNRRLQTRKEKAQALEELTGFRELFQTPCTDNPTTDEKTTKKILCKSPQ 1863
Query: 1504 SDPADTPTNTKQRPKRSLKKADVEEEFLAFRKLTPSAGKAMHTPKAAVGEEKDINTFVGT 1563
SDPADTPTNTKQRPKRSLKKADVEEEFLAFRKLTPSAGKAMHTPKAAVGEEKDINTFVGT
Sbjct: 1864 SDPADTPTNTKQRPKRSLKKADVEEEFLAFRKLTPSAGKAMHTPKAAVGEEKDINTFVGT 1923
Query: 1564 PVEKLDLLGNLPGSKRRPQTPKEKAKALEDLAGFKELFQTPGHTEESMTDDKITEVSCKS 1623
PVEKLDLLGNLPGSKRRPQTPKEKAKALEDLAGFKELFQTPGHTEESMTDDKITEVSCKS
Sbjct: 1924 PVEKLDLLGNLPGSKRRPQTPKEKAKALEDLAGFKELFQTPGHTEESMTDDKITEVSCKS 1983
Query: 1624 PQPDPVKTPTSSKQRLKISLGKVGVKEEVLPVGKLTQTSGKTTQTHRETAGDGKSIKAFK 1683
PQPDPVKTPTSSKQRLKISLGKVGVKEEVLPVGKLTQTSGKTTQTHRETAGDGKSIKAFK
Sbjct: 1984 PQPDPVKTPTSSKQRLKISLGKVGVKEEVLPVGKLTQTSGKTTQTHRETAGDGKSIKAFK 2043
Query: 1684 ESAKQMLDPANYGTGMERWPRTPKEEAQSLEDLAGFKELFQTPDHTEESTTDDKTTKIAC 1743
ESAKQMLDPANYGTGMERWPRTPKEEAQSLEDLAGFKELFQTPDHTEESTTDDKTTKIAC
Sbjct: 2044 ESAKQMLDPANYGTGMERWPRTPKEEAQSLEDLAGFKELFQTPDHTEESTTDDKTTKIAC 2103
Query: 1744 KSPPPESMDTPTSTRRRPKTPLGKRDIVEELSALKQLTQTTHTDKVPGDEDKGINVFRET 1803
KSPPPESMDTPTSTRRRPKTPLGKRDIVEELSALKQLTQTTHTDKVPGDEDKGINVFRET
Sbjct: 2104 KSPPPESMDTPTSTRRRPKTPLGKRDIVEELSALKQLTQTTHTDKVPGDEDKGINVFRET 2163
Query: 1804 AKQKLDPAASVTGSKRQPRTPKGKAQPLEDLAGLKELFQTPICTDKPTTHEKTTKIACRS 1863
AKQKLDPAASVTGSKRQPRTPKGKAQPLEDLAGLKELFQTPICTDKPTTHEKTTKIACRS
Sbjct: 2164 AKQKLDPAASVTGSKRQPRTPKGKAQPLEDLAGLKELFQTPICTDKPTTHEKTTKIACRS 2223
Query: 1864 PQPDPVGTPTIFKPQSKRSLRKADVEEESLALRKRTPSVGKAMDTPKPAGGDEKDMKAFM 1923
PQPDPVGTPTIFKPQSKRSLRKADVEEESLALRKRTPSVGKAMDTPKPAGGDEKDMKAFM
Sbjct: 2224 PQPDPVGTPTIFKPQSKRSLRKADVEEESLALRKRTPSVGKAMDTPKPAGGDEKDMKAFM 2283
Query: 1924 GTPVQKLDLPGNLPGSKRWPQTPKEKAQALEDLAGFKELFQTPGTDKPTTDEKTTKIACK 1983
GTPVQKLDLPGNLPGSKRWPQTPKEKAQALEDLAGFKELFQTPGTDKPTTDEKTTKIACK
Sbjct: 2284 GTPVQKLDLPGNLPGSKRWPQTPKEKAQALEDLAGFKELFQTPGTDKPTTDEKTTKIACK 2343
Query: 1984 SPQPDPVDTPASTKQRPKRNLRKADVEEEFLALRKRTPSAGKAMDTPKPAVSDEKNINTF 2043
SPQPDPVDTPASTKQRPKRNLRKADVEEEFLALRKRTPSAGKAMDTPKPAVSDEKNINTF
Sbjct: 2344 SPQPDPVDTPASTKQRPKRNLRKADVEEEFLALRKRTPSAGKAMDTPKPAVSDEKNINTF 2403
Query: 2044 VETPVQKLDLLGNLPGSKRQPQTPKEKAEALEDLVGFKELFQTPGHTEESMTDDKITEVS 2103
VETPVQKLDLLGNLPGSKRQPQTPKEKAEALEDLVGFKELFQTPGHTEESMTDDKITEVS
Sbjct: 2404 VETPVQKLDLLGNLPGSKRQPQTPKEKAEALEDLVGFKELFQTPGHTEESMTDDKITEVS 2463
Query: 2104 CKSPQPESFKTSRSSKQRLKIPLVKVDMKEEPLAVSKLTRTSGETTQTHTEPTGDSKSIK 2163
CKSPQPESFKTSRSSKQRLKIPLVKVDMKEEPLAVSKLTRTSGETTQTHTEPTGDSKSIK
Sbjct: 2464 CKSPQPESFKTSRSSKQRLKIPLVKVDMKEEPLAVSKLTRTSGETTQTHTEPTGDSKSIK 2523
Query: 2164 AFKESPKQILDPAASVTGSRRQLRTRKEKARALEDLVDFKELFSAPGHTEESMTIDKNTK 2223
AFKESPKQILDPAASVTGSRRQLRTRKEKARALEDLVDFKELFSAPGHTEESMTIDKNTK
Sbjct: 2524 AFKESPKQILDPAASVTGSRRQLRTRKEKARALEDLVDFKELFSAPGHTEESMTIDKNTK 2583
Query: 2224 IPCKSPPPELTDTATSTKRCPKTRPRKEVKEELSAVERLTQTSGQSTHTHKEPASGDEGI 2283
IPCKSPPPELTDTATSTKRCPKTRPRKEVKEELSAVERLTQTSGQSTHTHKEPASGDEGI
Sbjct: 2584 IPCKSPPPELTDTATSTKRCPKTRPRKEVKEELSAVERLTQTSGQSTHTHKEPASGDEGI 2643
Query: 2284 KVLKQRAKKKPNPVEEEPSRRRPRAPKEKAQPLEDLAGFTELSETSGHTQESLTAGKATK 2343
KVLKQRAKKKPNPVEEEPSRRRPRAPKEKAQPLEDLAGFTELSETSGHTQESLTAGKATK
Sbjct: 2644 KVLKQRAKKKPNPVEEEPSRRRPRAPKEKAQPLEDLAGFTELSETSGHTQESLTAGKATK 2703
Query: 2344 IPCESPPLEVVDTTASTKRHLRTRVQKVQVKEEPSAVKFTQTSGETTDADKEPAGEDKGI 2403
IPCESPPLEVVDTTASTKRHLRTRVQKVQVKEEPSAVKFTQTSGETTDADKEPAGEDKGI
Sbjct: 2704 IPCESPPLEVVDTTASTKRHLRTRVQKVQVKEEPSAVKFTQTSGETTDADKEPAGEDKGI 2763
Query: 2404 KALKESAKQTPAPAASVTGSRRRPRAPRESAQAIEDLAGFKDPAAGHTEESMTDDKTTKI 2463
KALKESAKQTPAPAASVTGSRRRPRAPRESAQAIEDLAGFKDPAAGHTEESMTDDKTTKI
Sbjct: 2764 KALKESAKQTPAPAASVTGSRRRPRAPRESAQAIEDLAGFKDPAAGHTEESMTDDKTTKI 2823
Query: 2464 PCKSSPELEDTATSSKRRPRTRAQKVEVKEELLAVGKLTQTSGETTHTDKEPVGEGKGTK 2523
PCKSSPELEDTATSSKRRPRTRAQKVEVKEELLAVGKLTQTSGETTHTDKEPVGEGKGTK
Sbjct: 2824 PCKSSPELEDTATSSKRRPRTRAQKVEVKEELLAVGKLTQTSGETTHTDKEPVGEGKGTK 2883
Query: 2524 AFKQPAKRKLDAEDVIGSRRQPRAPKEKAQPLEDLASFQELSQTPGHTEELANGAADSFT 2583
AFKQPAKRKLDAEDVIGSRRQPRAPKEKAQPLEDLASFQELSQTPGHTEELANGAADSFT
Sbjct: 2884 AFKQPAKRKLDAEDVIGSRRQPRAPKEKAQPLEDLASFQELSQTPGHTEELANGAADSFT 2943
Query: 2584 SAPKQTPDSGKPLKISRRVLRAPKVEPVGDVVSTRDPVKSQSKSNTSLPPLPFKRGGGKD 2643
SAPKQTPDSGKPLKISRRVLRAPKVEPVGDVVSTRDPVKSQSKSNTSLPPLPFKRGGGKD
Sbjct: 2944 SAPKQTPDSGKPLKISRRVLRAPKVEPVGDVVSTRDPVKSQSKSNTSLPPLPFKRGGGKD 3003
Query: 2644 GSVTGTKRLRCMPAPEEIVEELPASKKQRVAPRARGKSSEPVVIMKRSLRTSAKRIEPAE 2703
GSVTGTKRLRCMPAPEEIVEELPASKKQRVAPRARGKSSEPVVIMKRSLRTSAKRIEPAE
Sbjct: 3004 GSVTGTKRLRCMPAPEEIVEELPASKKQRVAPRARGKSSEPVVIMKRSLRTSAKRIEPAE 3063
Query: 2704 ELNSNDMKTNKEEHKLQDSVPENKGISLRSRRQNKTEAEQQITEVFVLAERIEINRNEKK 2763
ELNSNDMKTNKEEHKLQDSVPENKGISLRSRRQNKTEAEQQITEVFVLAERIEINRNEKK
Sbjct: 3064 ELNSNDMKTNKEEHKLQDSVPENKGISLRSRRQNKTEAEQQITEVFVLAERIEINRNEKK 3123
Query: 2764 PMKTSPEMDIQNPDDGARKPIPRDKVTENKRCLRSARQNESSQPKVAEESGGQKSAKVLM 2823
PMKTSPEMDIQNPDDGARKPIPRDKVTENKRCLRSARQNESSQPKVAEESGGQKSAKVLM
Sbjct: 3124 PMKTSPEMDIQNPDDGARKPIPRDKVTENKRCLRSARQNESSQPKVAEESGGQKSAKVLM 3183
Query: 2824 QNQKGKGEAGNSDSMCLRSRKTKSQPAASTLESKSVQRVTRSVKRCAENPKKAEDNVCVK 2883
QNQKGKGEAGNSDSMCLRSRKTKSQPAASTLESKSVQRVTRSVKRCAENPKKAEDNVCVK
Sbjct: 3184 QNQKGKGEAGNSDSMCLRSRKTKSQPAASTLESKSVQRVTRSVKRCAENPKKAEDNVCVK 3243
Query: 2884 KIRTRSHRDSEDI 2896
KIRTRSHRDSEDI
Sbjct: 3244 KIRTRSHRDSEDI 3256
Score = 276 bits (707), Expect = 2e-73
Identities = 135/135 (100%), Positives = 135/135 (100%)
Query: 1 MWPTRRLVTIKRSGVDGPHFPLSLSTCLFGRGIECDIRIQLPVVSKQHCKIEIHEQEAIL 60
MWPTRRLVTIKRSGVDGPHFPLSLSTCLFGRGIECDIRIQLPVVSKQHCKIEIHEQEAIL
Sbjct: 1 MWPTRRLVTIKRSGVDGPHFPLSLSTCLFGRGIECDIRIQLPVVSKQHCKIEIHEQEAIL 60
Query: 61 HNFSSTNPTQVNGSVIDEPVRLKHGDVITIIDRSFRYENESLQNGRKSTEFPRKIREQEP 120
HNFSSTNPTQVNGSVIDEPVRLKHGDVITIIDRSFRYENESLQNGRKSTEFPRKIREQEP
Sbjct: 61 HNFSSTNPTQVNGSVIDEPVRLKHGDVITIIDRSFRYENESLQNGRKSTEFPRKIREQEP 120
Query: 121 ARRVSRSSFSSDPDE 135
ARRVSRSSFSSDPDE
Sbjct: 121 ARRVSRSSFSSDPDE 135
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 98.2 bits (243), Expect = 1e-19
Identities = 234/1070 (21%), Positives = 355/1070 (33%), Gaps = 136/1070 (12%)
Query: 1331 TGSKRQLRTPKGKSEVPEDLAGFIELFQTPSHTKE---SMTNEKTTKVSYRASQPDLVDT 1387
+G+ + +++ +S P + ++ ++ T+E S E ++ S +S +
Sbjct: 82 SGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSSSSSSSSSTIRKI 141
Query: 1388 PTSSKPQPKRSLRKADTEEEFLAFRKQTPSAGKAMHTPKPAVGEEKDINTFLGTPVQKLD 1447
+S R L+K L + + K TPKP V +E G+ + D
Sbjct: 142 KSSKNSAANRELQKK------LKVKDNKKNRTKKKPTPKPPVVDEA------GSGLDNGD 189
Query: 1448 QPGNLPGSNRRLQTRKEKAQALEELTGFRELFQTPCTDNPTTDEKTTKKILCKSPQSDPA 1507
P ++ T+ K ++T + + P + K T + K +
Sbjct: 190 FKVTTPDTST---TQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETK 246
Query: 1508 DTPTNTKQRPKRSLKKADVEEEFLAFRK-----LTPSAGK-AMHTPKAAVGEEKDINTFV 1561
+T T KQ +K +E + K L P++ A TPKA + T
Sbjct: 247 ETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALT-- 304
Query: 1562 GTPVEKLDLLGNLPGSKRRPQTPKEKAKALEDLAGFKELFQTPGHTEESMTDDKITEVSC 1621
TP E P TPKE A TP E + T K +
Sbjct: 305 -TPKEPT------------PTTPKEPAST------------TP--KEPTPTTIKSAPTTP 337
Query: 1622 KSPQPDPVKT-PTSSKQRLKISLGKVGVKEEVLPVGKLTQTSGKTTQTHRETAGDGKSIK 1680
K P P K+ PT+ K+ + + P T+ TT T +
Sbjct: 338 KEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPT 397
Query: 1681 AFKESAKQMLDPANYGTGMERWPRTPKEEAQSLEDLAGFKELFQTPDHTEESTTDDKTTK 1740
K+ A T E P TPKE A + KE T T K
Sbjct: 398 TPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTT------KEPAPTTPKEPAPTAPKKPAP 451
Query: 1741 IACKSPPPESMDTPTSTRRRPKTPLGKRDIVEELSALKQLTQTTHTDKVPGDEDKGINVF 1800
K P P + P T + +P + E + TT + P
Sbjct: 452 TTPKEPAPTTPKEPAPTTTKEPSPTTPK---EPAPTTTKSAPTTTKEPAPTTTKSAPTTP 508
Query: 1801 RETAKQKLDPAASVTGSKRQPRTPKGKAQPLEDLAGLKELFQTPICTDKPTTHEKTTKIA 1860
+E + A T + P TPK A KE T PTT +K
Sbjct: 509 KEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTP-----KEPAPTTPKEPAPTTTKKPAPTT 563
Query: 1861 CRSPQPDPVGTPTIFKPQSKRSLRKADVEEESLALRKRTPSVGKAMDTPKPAGGDEKDMK 1920
+ P P TP P + + L E+ L TP + P P +E
Sbjct: 564 PKEPAPT---TPKETAPTTPKKLTPTTPEK----LAPTTP------EKPAPTTPEELAPT 610
Query: 1921 AFMGTPVQKLDLPGNLPGSKRWPQTPKEKAQALEDLAGFKELFQTPGTDKPTTDEKTTKI 1980
+ P P TPKE A + TP PTT ++T
Sbjct: 611 TPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPK----EPAPTTPKEPAPTTPKETAPT 666
Query: 1981 ACKSPQPDPVDTPAST---KQRPKRNLRKADVEEEFLALRKRTPSA--GKAMDTPK-PAV 2034
K P + PA T K PK E K P+ G A TPK PA
Sbjct: 667 TPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAP 726
Query: 2035 SDEKNINTFVETPVQKLDLLGNLPGSKRQPQ--TPKEKAEALEDLVGFKELFQTPGHTEE 2092
+ K TP G P + ++P TPK+ A KEL T
Sbjct: 727 TTPKE--PAPTTPK------GTAPTTLKEPAPTTPKKPAP--------KELAPTTTKGPT 770
Query: 2093 SMTDDKITEVSCKSPQPESFKTSRSSKQRLKIPLVKVDMKEEPLAVSKLTRTSGETTQTH 2152
S T DK + K P + K + + P VS T T E T H
Sbjct: 771 STTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTK-EPTTIH 829
Query: 2153 TEPTGDSKSI------KAFKESPKQILDPAASVTGSRRQLRTRKEKARALE-DLVDFKEL 2205
P + + KA + SPK+ P + + T K + E DL E
Sbjct: 830 KSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPET 889
Query: 2206 FSA-PGHTEESMTI-DKNTKIPCKSPPPELTDTAT------------STKRCPKTRPRKE 2251
+A P T+E+ T +K T+ + ++T T T +T PK K+
Sbjct: 890 TTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKK 949
Query: 2252 VKEELSAVERLTQTSGQSTHTHKEPASGDEGIKVLKQRAKKKPNPVEEEPSRRRPRAPKE 2311
+ + +T+ A+ + K K A KKP ++ + R R PK
Sbjct: 950 TITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTK--APKKPTSTKKPKTMPRVRKPKT 1007
Query: 2312 KAQPLEDLAGFTELSETSGHTQESLTAGKATKIPCESPPLEVVDTTASTK 2361
P + + EL+ TS + L + T P ++P ++V+ ++
Sbjct: 1008 TPTPRKMTSTMPELNPTSRIAEAML---QTTTRPNQTPNSKLVEVNPKSE 1054
Score = 97.4 bits (241), Expect = 2e-19
Identities = 266/1125 (23%), Positives = 376/1125 (33%), Gaps = 170/1125 (15%)
Query: 440 PTSESFGGNVFFSAQNAAKQPSDKCSASPPLRRQCIRENGNVAKTPRNTYKMTS-LETKT 498
P ESF V N PS K + P Q I+ + P N K +E++
Sbjct: 57 PDYESFCAEV----HNPTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEE 112
Query: 499 SDTETEPSKTVSTANRSGRSTEFRNIQKLPVESKSEETNTEIVECILKRGQKATLLQQRR 558
E S+ +++ S S+ I+K+ SK+ N E+ + + + K +
Sbjct: 113 ITEEHSVSENQESSSSSSSSSSSSTIRKIK-SSKNSAANRELQKKLKVKDNK------KN 165
Query: 559 EGEMKEIERPFETYKENIELKENDEKMKAMKRSRTWGQKCAPMSDLTDLKSL-------P 611
+ K +P + L D K+ S T K + +T K + P
Sbjct: 166 RTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPP 225
Query: 612 DTELMKDTARGQNLLQTQDHAKAPKSEKGKIT--KMPCQSLQPEPINTPTHTKQQLKAS- 668
+++ K+T+ N T + + + K T K S + T K S
Sbjct: 226 NSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSK 285
Query: 669 -LGKVGVKEELLAVGKFTRTSGE-TTHTHREPAG---DGKSIRTFKESPKQILDPAARVT 723
L K K E G T E T T +EPA + T K +P +PA T
Sbjct: 286 VLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTT 345
Query: 724 GMKKWPRTPKEEAQSLEDLAGFKELFQTPGPSEESMTDEKTTKIACKSPPPESVDTPTST 783
K P TPKE A + + P P+ TTK + P + PT+
Sbjct: 346 --KSAPTTPKEPAPTTT---------KEPAPTTPKEPAPTTTK---EPAPTTTKSAPTTP 391
Query: 784 KQ----WPKRSLRKADVEEEFLALRKLTPSAGKAMLTPKPAGGDEKDIKAFMGTPVQKLD 839
K+ PK+ E ++ TP+ TPK K+ P +
Sbjct: 392 KEPAPTTPKKPAPTTPKEPAPTTPKEPTPT------TPKEPAPTTKE-----PAPTTPKE 440
Query: 840 LAGTLPGSKRQLQTPKEKAQALEDLAGFKELFQTPGHTEELVAAGKTTKIPCDSPQSDPV 899
A T P K TPKE P T A TTK P SP +
Sbjct: 441 PAPTAP-KKPAPTTPKE-----------------PAPTTPKEPAPTTTKEP--SPTTPKE 480
Query: 900 DTPTSTKQRPKRSIRKADVEGELLACRNLMPSAGKAMHTPKPSVGEEKDIIIFVGTPVQK 959
PT+TK P + A + SA P P+ +E TP +
Sbjct: 481 PAPTTTKSAPTTTKEPAPTTTK---------SAPTTPKEPSPTTTKEP----APTTPKEP 527
Query: 960 LDLTENLTGSKRRPQTPKEEAQALEDLTGFKELFQTPGHTEEAVAAGKTTKMPCESSPPE 1019
T K P TPKE P T A TTK P ++P E
Sbjct: 528 APTTP----KKPAPTTPKE-----------------PAPTTPKEPAPTTTKKPAPTTPKE 566
Query: 1020 SADTPTSTRRQPKTPLEKRDVQKELSALKKLTQTSGE----TTHTDKVP-GGEDKSINAF 1074
A T T P TP + E KL T+ E TT + P E+ +
Sbjct: 567 PAPT-TPKETAPTTPKKLTPTTPE-----KLAPTTPEKPAPTTPEELAPTTPEEPTPTTP 620
Query: 1075 RETAKQKLDPAASVTGSKRHPKTKEKAQPLEDLAGLKELFQTPVCTDKPTTHEKTTKIAC 1134
E A AA T + P T ++ P KE T PTT + T
Sbjct: 621 EEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTP----KEPAPTTPKETAPTTPKGTAPTTL 676
Query: 1135 RSQPDPVDTPTSSKPQSKRSLRKVDVEEEFFALRKRTPSA--GKAMHTPK-PAVSGEKNI 1191
+ +P P T KP K E K P+ G A TPK PA +
Sbjct: 677 K-EPAPT---TPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPT----- 727
Query: 1192 YAFMGTPVQKLDLTENLTGSKRRLQTPKEKAQALEDLAGFKELFQTRGHTEESMTNDKTA 1251
TP + T T T KE A KEL T S T+DK A
Sbjct: 728 -----TPKEPAPTTPKGTAP----TTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPA 778
Query: 1252 KVACKSSQPDPDKNPASSKRRLKTSLGKVGVKEELLAVGKLTQTSGETTHTHTEPTGDGK 1311
K + P K PA + + V T T+ E T H P
Sbjct: 779 PTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPT-TTKEPTTIHKSPDESTP 837
Query: 1312 SM------KAFMESPKQI-LDSAASLTGSKRQLRTPKGKSEVPEDLAGFIE-LFQTPSHT 1363
+ KA SPK+ + + + +K ++ T DL E P T
Sbjct: 838 ELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMT 897
Query: 1364 KE-SMTNEKTTKVSYRASQPDLVDTPTSSKPQPKRSLRKADTEEEFLAFRKQTPSAGKAM 1422
KE + T EKTT+ A+ + T T K + K T + K+T + + M
Sbjct: 898 KETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIM 957
Query: 1423 HTPKPAVGEEKDINTFLGTPVQKLDQPGNLPGSNRRLQTRKEKAQALEELTGFRELFQTP 1482
+ P+ + KD T K +P P + T+K K + R+ TP
Sbjct: 958 NKPE-ETAKPKDRATNSKATTPKPQKPTKAP--KKPTSTKKPKT-----MPRVRKPKTTP 1009
Query: 1483 CTDNPTTDEKTTKKILCKSPQSDPADTPTNTKQRPKRSLKKADVE 1527
T K T + +P S A+ T RP ++ VE
Sbjct: 1010 ------TPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVE 1048
Score = 80.5 bits (197), Expect = 2e-14
Identities = 219/1040 (21%), Positives = 330/1040 (31%), Gaps = 154/1040 (14%)
Query: 1620 SCKSPQPDPVK------TPTSSKQRLKISLGKVGVKEEVLPVGKLTQTSGKTTQTHRETA 1673
S K+P P T S K K KV EE+ +++ ++ + ++
Sbjct: 75 SKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSSSSSSS 134
Query: 1674 GDG-KSIKAFKESAK--------QMLDPANYGTGMERWPRTPK-EEAQSLEDLAGFKELF 1723
+ IK+ K SA ++ D T + P+ P +EA S D FK
Sbjct: 135 SSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFK--V 192
Query: 1724 QTPD-----HTEESTTDDKTTKIACKSPPPESMDTPTSTRRRPKTPLGKRDIVEELSALK 1778
TPD H + ST+ TT A P S+ + T + + K VE
Sbjct: 193 TTPDTSTTQHNKVSTSPKITT--AKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTT 250
Query: 1779 QLTQTTHTDKVPGDEDKGINVFRETAKQKLDPAASVTG--SKRQPRTPKGKAQPLEDLAG 1836
QT+ K K +T+ + L P + V + + T KG A L
Sbjct: 251 TNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPA-----LTT 305
Query: 1837 LKELFQTPICTDKPTTHEKTTKIACRSPQPDPVG----TPTIFKPQSKRSLRKADVEEES 1892
KE PTT ++ + P P + TP P + +S E
Sbjct: 306 PKE--------PTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAP 357
Query: 1893 LALRKRTPSVGKAMDTPKPAGGDEKDMKAFMGTPVQKLDLPGNLPGSKRWPQTPKEKAQA 1952
++ P+ K P P E P + P K P TPKE A
Sbjct: 358 TTTKEPAPTTPKE---PAPTTTKEPAPTTTKSAPTTPKE-PAPTTPKKPAPTTPKEPAPT 413
Query: 1953 LEDLAGFKELFQTPGTDKPTTDEKTTKIACKSPQPDPVDTPASTKQRPKRNLRKADVEEE 2012
TP PTT ++ K P P PA T PK+ E
Sbjct: 414 ------------TPKEPTPTTPKEPAPTT-KEPAPTTPKEPAPTA--PKKPAPTTPKEPA 458
Query: 2013 FLALRKRTPSAGK--AMDTPK-PAVSDEKNINTFVETPVQKLDLLGNLPGSKRQPQTPKE 2069
++ P+ K + TPK PA + K+ T + P +K P TPKE
Sbjct: 459 PTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTT--------TKSAPTTPKE 510
Query: 2070 KAEALEDLVGFKELFQTPGHTEESMTDDKITEVSCKSPQPESFKTSRSSKQRLKIPLVKV 2129
+ KE T T K + K P P + K + + P
Sbjct: 511 PSPTTT-----KEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTP- 564
Query: 2130 DMKEEPLAVSKLTRTSGETTQTHTEPTGDSKSIKAFKESPKQILDPAASVTGSRRQLRTR 2189
+EP + + + TT PT K E P + T T
Sbjct: 565 ---KEPAPTTP--KETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTT 619
Query: 2190 KEKARALEDLVDFKELFSAPGHTEESMTIDKNTKIPCKSPPPELTDTA------TSTKRC 2243
E+ P T K P + P E T T+ K
Sbjct: 620 PEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEP 679
Query: 2244 PKTRPRKEVKEELSAVERLTQTSGQSTHTHKEPASGDEGIKVLKQRAKKKPNPVEEEPSR 2303
T P+K +EL+ T KEP S KP P P
Sbjct: 680 APTTPKKPAPKELAPT------------TTKEPTS----------TTCDKPAPTT--PKG 715
Query: 2304 RRPRAPKEKAQPLEDLAGFTELSETSGHTQESLTAGKATKIPCESPPLEVVDTTASTKRH 2363
P PKE A T T+ T + A P + P E+ TT
Sbjct: 716 TAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKE----PAPTTPKKPAPKELAPTT------ 765
Query: 2364 LRTRVQKVQVKEEPSAVKFTQTSGETTDADKEPAGEDKGIKALKESAKQTPAPAASVTGS 2423
T+ ++P+ +T+ TT + P K E+ T + ++ T +
Sbjct: 766 --TKGPTSTTSDKPAPTTPKETA-PTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTT 822
Query: 2424 RRRPRAPRESAQAIEDLAGFKDPAAGHTEESMTDDKTTKIPCKSSPELEDTATSS----- 2478
+ + ++ +L+ P A TTK P + PE+ TA
Sbjct: 823 KEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERD 882
Query: 2479 -KRRPRTRAQKVEVKEELLAVGKLTQTSGETTHTDKEPVGEGKGTKAFK-------QPAK 2530
+ P T ++ +E + T S T T + + T FK A
Sbjct: 883 LRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAP 942
Query: 2531 RKLDAEDVIGSRRQPRAPKEKAQPLEDLASFQELSQTPGHTEELANGAADSFTSAPKQTP 2590
+ + I + P+E A+P + + + + P T APK+
Sbjct: 943 KVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKP-----------QKPTKAPKKPT 991
Query: 2591 DSGKPLKISRRVLRAPKVEP 2610
+ KP + R +R PK P
Sbjct: 992 STKKPKTMPR--VRKPKTTP 1009
Score = 66.6 bits (161), Expect = 3e-10
Identities = 229/1059 (21%), Positives = 337/1059 (31%), Gaps = 136/1059 (12%)
Query: 1008 TTKMPCESSPPESADTPT---STRRQPKTP--------LEKRDVQKELSALKKLTQTSGE 1056
T+ + +PP S + T +T+R PK P +E ++ +E S + +S
Sbjct: 70 TSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSS 129
Query: 1057 TTHTDKVPGGEDKSINAFRETAKQKLDPAASVTGSKRHPKTKEKAQP---LEDLAGL--- 1110
++ + + KS A ++L V +K++ +TK+K P + D AG
Sbjct: 130 SSSSSSSTIRKIKSSK--NSAANRELQKKLKVKDNKKN-RTKKKPTPKPPVVDEAGSGLD 186
Query: 1111 KELFQTPVCTDKPTTHEKTTKIACRSQPDPVDTPTSSKPQSKRSLR-KVDVEEEFFALRK 1169
F+ T H K + + P++ S P S S + V +E K
Sbjct: 187 NGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETK 246
Query: 1170 RTPSAGKAMHTPKPAVSGEKNIYAFMGTPVQKLDLTENLTGSKRRLQTPKEKAQALED-- 1227
T + K T EK A ++K ++L + + L P KA+
Sbjct: 247 ETTTTNKQTSTD----GKEKTTSAKETQSIEKTS-AKDLAPTSKVLAKPTPKAETTTKGP 301
Query: 1228 -LAGFKELFQTRGHTEESMTNDKTAKVACKSSQPDPDKNPASSKRRLKTSLGKVGVKEEL 1286
L KE T S T + KS+ P K PA + + + K
Sbjct: 302 ALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTP-KEPAPTTTKSAPTTPK------- 353
Query: 1287 LAVGKLTQTSGETTHTHTEPTGDGKSMKAFMESPKQILDSAASLTGSKRQLRTPKGKSEV 1346
TT PT + + P +A T + TPK +
Sbjct: 354 --------EPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPT 405
Query: 1347 -PEDLAGFIELFQTPSHTKESMTNEK----TTKVSYRASQPDLVDTPTSSKPQPKRSLRK 1401
P++ A TP+ KE K TT + P T +P P
Sbjct: 406 TPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEP 465
Query: 1402 ADTEEEFLAFRKQTPSAGKAMHTPKPAVGEEKDINTFLGTPVQKLDQPGNLPGSNRRLQT 1461
A T ++ +P+ K +PA K T P + T
Sbjct: 466 APTTT-----KEPSPTTPK-----EPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTT 515
Query: 1462 RKEKAQALEELTGFRELFQTPCTDNPTTDEK---TTKKILCKSPQSDPADTPTNTKQ--- 1515
KE A TP PTT +K TT K + +PA PT TK+
Sbjct: 516 TKEPAPT------------TPKEPAPTTPKKPAPTTPKEPAPTTPKEPA--PTTTKKPAP 561
Query: 1516 -RPKRSLKKADVEEEFLAFRKLTPSAGKAMHTPKAAVGEEKDINTFVGTPVEKLDLLGNL 1574
PK E +KLTP+ + + A EK T TP E L
Sbjct: 562 TTPKEPAPTTPKETAPTTPKKLTPTTPEKL----APTTPEKPAPT---TPEE----LAPT 610
Query: 1575 PGSKRRPQTPKEKAKALEDLAGF---KELFQTPGHTEESMTDDKITEVSCKSPQPDPVK- 1630
+ P TP+E A A KE T T + + K P K
Sbjct: 611 TPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKG 670
Query: 1631 -TPTSSKQRLKISLGKVGVKEEVLPVGKLTQTSGKTTQTHRETAGDGKSIKAFKESAKQM 1689
PT+ K+ + K KE K + + T T G + KE A
Sbjct: 671 TAPTTLKEPAPTTPKKPAPKELAPTTTK--EPTSTTCDKPAPTTPKGTAPTTPKEPAPTT 728
Query: 1690 LDPANYGTGMERWPRTPKEEAQSLEDLAGFKELFQTPDHTEESTTDDKTTKIACKSPPPE 1749
T P T KE A + KEL T STT DK K P
Sbjct: 729 PKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPT 788
Query: 1750 SMDTPTST---RRRPKTPLGKRDIVEELSALKQLTQTTHTDKVPGDEDKGINVFRETAKQ 1806
+ P T + P TP E+S + T K P + ++ E +
Sbjct: 789 TPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSA--EPTPK 846
Query: 1807 KLDPAASVTG---SKRQPRTPKGKAQPLEDLAGLKELFQTPICT--------DKPTTHEK 1855
L+ + G +K T +D ++L TP T + TT EK
Sbjct: 847 ALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEK 906
Query: 1856 TTKIACRSPQPDPVGTPTIFKPQSKRSLRKADVEEESLALRKRTPSVGKAMDTPKPAGGD 1915
TT+ + T T K + K + K+T + + M+ P+
Sbjct: 907 TTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEET-AK 965
Query: 1916 EKDMKAFMGTPVQKLDLPGNLPGSKRWPQTPKEKAQALEDLAGFKELFQTPGTDKPTTDE 1975
KD K P P K+ T K K P KP T
Sbjct: 966 PKDRATNSKATTPKPQKPTKAP--KKPTSTKKPKTM--------------PRVRKPKTTP 1009
Query: 1976 KTTKIACKSPQPDPVDTPA----STKQRPKRNLRKADVE 2010
K+ P+ +P A T RP + VE
Sbjct: 1010 TPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVE 1048
Score = 50.8 bits (120), Expect = 2e-05
Identities = 99/498 (19%), Positives = 164/498 (32%), Gaps = 53/498 (10%)
Query: 2058 PGSKRQPQTPKEKAEALEDLVGFKELFQTPGHTEESMTDDKITEVSCKSPQPESFKTSRS 2117
P SK+ P P ++ ++ T++ + ++ITE S ES +S S
Sbjct: 73 PSSKKAPP-PSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSSSS 131
Query: 2118 SKQRLKIPLVKVDMKEEPLAVSKLTRTSGETTQTHTEPTGDSKSIKAFKESPKQILDPAA 2177
S I +K S + Q + + K+ K +PK P
Sbjct: 132 SSSSSTIRKIK----------SSKNSAANRELQKKLKVKDNKKNRTKKKPTPKP---PVV 178
Query: 2178 SVTGSRRQLRTRKEKARALEDLVDFKELFSAPGHTEESM--TIDKNTKIPCKSPPPELTD 2235
GS D DFK T+ + T K T +P P L
Sbjct: 179 DEAGSGL-------------DNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPP 225
Query: 2236 TATSTKRCPKTRPRKEVKEELSAVERLTQTSGQSTHTH-KEPASGDEGIKVLKQRAKKKP 2294
+ ++K T V +E + + T T+ + T T KE + + + +++ + K
Sbjct: 226 NSDTSKETSLT-----VNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDL 280
Query: 2295 NPVEEEPSRRRPRAPKEKAQPLEDLAGFTELSETSGHTQESLTAGKATKIPCESPPLEVV 2354
P + ++ P+A P T E + T + A+ P E P +
Sbjct: 281 APTSKVLAKPTPKAETTTKGP-----ALTTPKEPTPTTPKE----PASTTPKEPTPTTIK 331
Query: 2355 DTTASTKRHLRTRVQKVQVKEEPSAVKFTQTSGETTDADKEPAGEDKGIKALKESAKQTP 2414
+ K T + + A T+ TT + P + +SA TP
Sbjct: 332 SAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTP 391
Query: 2415 APAASVTGSRRRPRAPRESAQAIEDLAGFKDPAAGHTEESMTDDKTTKIPCKSSPELEDT 2474
A T + P P+E A K+P +E TTK P ++P+ E
Sbjct: 392 KEPAPTTPKKPAPTTPKEPAPTTP-----KEPTPTTPKEPA---PTTKEPAPTTPK-EPA 442
Query: 2475 ATSSKRRPRTRAQKVEVKEELLAVGKLTQTSGETTHTDKEPVGEGKGTKAFKQPAKRKLD 2534
T+ K+ T ++ T+ TT + P K+PA
Sbjct: 443 PTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTK 502
Query: 2535 AEDVIGSRRQPRAPKEKA 2552
+ P KE A
Sbjct: 503 SAPTTPKEPSPTTTKEPA 520
Score = 38.9 bits (89), Expect = 0.075
Identities = 102/461 (22%), Positives = 150/461 (32%), Gaps = 88/461 (19%)
Query: 634 APKSEKGKITKMPCQSLQPEPI-NTPTHTKQQLKASLGKVGVKEELLAVGKFTRTSGETT 692
APK TK P + +P TP T KE K G
Sbjct: 688 APKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPK-----GTAP 742
Query: 693 HTHREPAGDGKSIRTFKESPKQILDPAAR----VTGMKKWPRTPKEEAQSLEDLAGFKEL 748
T +EPA K +PK++ + T K P TPKE A +
Sbjct: 743 TTLKEPAPTTPK----KPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTP-------- 790
Query: 749 FQTPGPSEESMTDEKTTKIACKSPPPES--VDTPTSTKQWPKRSLRKADVEEEFLALRKL 806
+ P P+ T +K ++PPP + V TPT+TK+ ++ K+ E
Sbjct: 791 -KEPAPT----TPKKPAPTTPETPPPTTSEVSTPTTTKE--PTTIHKSPDES-------- 835
Query: 807 TPSAGKAMLTPKPAGGDEKDIKAFMGTPVQKLDLAGTLPGSKRQLQTPKEKAQALEDLAG 866
TP A TPK K+ G P K A T E +D
Sbjct: 836 TPELS-AEPTPKALENSPKE----PGVPTTKTPAA-----------TKPEMTTTAKDKTT 879
Query: 867 FKELFQTPGHTEELVAAGKTTKIPCDSPQSDPVDTPTSTKQRPKRSIRKADVEGELLACR 926
++L TP E AA K TK +T T+T++ + I + +
Sbjct: 880 ERDLRTTP---ETTTAAPKMTK-----------ETATTTEKTTESKITATTTQVTSTTTQ 925
Query: 927 NLMPSAGKAMHTPKPSVGEEKDIIIFVGTPVQKLDLTENLTGSKRRPQTPKEEAQALEDL 986
+ P + T T K+ T+ + P+E A+ +
Sbjct: 926 DTTPFKITTLKTT---------------TLAPKVTTTKKTITTTEIMNKPEETAKPKDRA 970
Query: 987 TGFKELFQTPGHTEEAVAAGKTTKMPCESSPPESADTPTSTRRQPKTPLEKRDVQKELSA 1046
T K P +A +TK P T + R+ T E + A
Sbjct: 971 TNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEA 1030
Query: 1047 LKKLTQTSGETTHTDKV---PGGEDKSINAFRETAKQKLDP 1084
+ + T +T ++ V P ED A ET L P
Sbjct: 1031 MLQTTTRPNQTPNSKLVEVNPKSEDAG-GAEGETPHMLLRP 1070
Score = 35.0 bits (79), Expect = 1.1
Identities = 57/264 (21%), Positives = 97/264 (36%), Gaps = 27/264 (10%)
Query: 2636 FKRGGGKDGSVTGTKRLRCMPAPEEIVEEL------PASKKQRVAPRARGKSSEPVVIMK 2689
F+RG D K +C P E E+ P+SKK AP G S K
Sbjct: 37 FERGRECDCDAQCKKYDKCCPDYESFCAEVHNPTSPPSSKK---APPPSGASQTIKSTTK 93
Query: 2690 RSLRTSAKR-----IEPAEELNSNDMKTNKEEHKLQDSVPENKGISLRSRRQNKTEAEQQ 2744
RS + K+ IE E + + N+E S + ++R + +K A +
Sbjct: 94 RSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSSSS--SSSSSTIRKIKSSKNSAANR 151
Query: 2745 ITEVFVLAERIEINRNEKKPMKTSPEMDIQNP--DDGARK-PIPRDKVTENKRCLRSARQ 2801
+ + + + NR +KKP P +D D+G K P T++ + S +
Sbjct: 152 ELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKI 211
Query: 2802 NESS----QPKVAEESGGQKSAKVLMQN----QKGKGEAGNSDSMCLRSRKTKSQPAAST 2853
+ +P + S K + + + + N + KT S +
Sbjct: 212 TTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQS 271
Query: 2854 LESKSVQRVTRSVKRCAENPKKAE 2877
+E S + + + K A+ KAE
Sbjct: 272 IEKTSAKDLAPTSKVLAKPTPKAE 295
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 98.2 bits (243), Expect = 1e-19
Identities = 234/1070 (21%), Positives = 355/1070 (33%), Gaps = 136/1070 (12%)
Query: 1331 TGSKRQLRTPKGKSEVPEDLAGFIELFQTPSHTKE---SMTNEKTTKVSYRASQPDLVDT 1387
+G+ + +++ +S P + ++ ++ T+E S E ++ S +S +
Sbjct: 123 SGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSSSSSSSSSTIRKI 182
Query: 1388 PTSSKPQPKRSLRKADTEEEFLAFRKQTPSAGKAMHTPKPAVGEEKDINTFLGTPVQKLD 1447
+S R L+K L + + K TPKP V +E G+ + D
Sbjct: 183 KSSKNSAANRELQKK------LKVKDNKKNRTKKKPTPKPPVVDEA------GSGLDNGD 230
Query: 1448 QPGNLPGSNRRLQTRKEKAQALEELTGFRELFQTPCTDNPTTDEKTTKKILCKSPQSDPA 1507
P ++ T+ K ++T + + P + K T + K +
Sbjct: 231 FKVTTPDTST---TQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETK 287
Query: 1508 DTPTNTKQRPKRSLKKADVEEEFLAFRK-----LTPSAGK-AMHTPKAAVGEEKDINTFV 1561
+T T KQ +K +E + K L P++ A TPKA + T
Sbjct: 288 ETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALT-- 345
Query: 1562 GTPVEKLDLLGNLPGSKRRPQTPKEKAKALEDLAGFKELFQTPGHTEESMTDDKITEVSC 1621
TP E P TPKE A TP E + T K +
Sbjct: 346 -TPKEPT------------PTTPKEPAST------------TP--KEPTPTTIKSAPTTP 378
Query: 1622 KSPQPDPVKT-PTSSKQRLKISLGKVGVKEEVLPVGKLTQTSGKTTQTHRETAGDGKSIK 1680
K P P K+ PT+ K+ + + P T+ TT T +
Sbjct: 379 KEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPT 438
Query: 1681 AFKESAKQMLDPANYGTGMERWPRTPKEEAQSLEDLAGFKELFQTPDHTEESTTDDKTTK 1740
K+ A T E P TPKE A + KE T T K
Sbjct: 439 TPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTT------KEPAPTTPKEPAPTAPKKPAP 492
Query: 1741 IACKSPPPESMDTPTSTRRRPKTPLGKRDIVEELSALKQLTQTTHTDKVPGDEDKGINVF 1800
K P P + P T + +P + E + TT + P
Sbjct: 493 TTPKEPAPTTPKEPAPTTTKEPSPTTPK---EPAPTTTKSAPTTTKEPAPTTTKSAPTTP 549
Query: 1801 RETAKQKLDPAASVTGSKRQPRTPKGKAQPLEDLAGLKELFQTPICTDKPTTHEKTTKIA 1860
+E + A T + P TPK A KE T PTT +K
Sbjct: 550 KEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTP-----KEPAPTTPKEPAPTTTKKPAPTT 604
Query: 1861 CRSPQPDPVGTPTIFKPQSKRSLRKADVEEESLALRKRTPSVGKAMDTPKPAGGDEKDMK 1920
+ P P TP P + + L E+ L TP + P P +E
Sbjct: 605 PKEPAPT---TPKETAPTTPKKLTPTTPEK----LAPTTP------EKPAPTTPEELAPT 651
Query: 1921 AFMGTPVQKLDLPGNLPGSKRWPQTPKEKAQALEDLAGFKELFQTPGTDKPTTDEKTTKI 1980
+ P P TPKE A + TP PTT ++T
Sbjct: 652 TPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPK----EPAPTTPKEPAPTTPKETAPT 707
Query: 1981 ACKSPQPDPVDTPAST---KQRPKRNLRKADVEEEFLALRKRTPSA--GKAMDTPK-PAV 2034
K P + PA T K PK E K P+ G A TPK PA
Sbjct: 708 TPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAP 767
Query: 2035 SDEKNINTFVETPVQKLDLLGNLPGSKRQPQ--TPKEKAEALEDLVGFKELFQTPGHTEE 2092
+ K TP G P + ++P TPK+ A KEL T
Sbjct: 768 TTPKE--PAPTTPK------GTAPTTLKEPAPTTPKKPAP--------KELAPTTTKGPT 811
Query: 2093 SMTDDKITEVSCKSPQPESFKTSRSSKQRLKIPLVKVDMKEEPLAVSKLTRTSGETTQTH 2152
S T DK + K P + K + + P VS T T E T H
Sbjct: 812 STTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTK-EPTTIH 870
Query: 2153 TEPTGDSKSI------KAFKESPKQILDPAASVTGSRRQLRTRKEKARALE-DLVDFKEL 2205
P + + KA + SPK+ P + + T K + E DL E
Sbjct: 871 KSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPET 930
Query: 2206 FSA-PGHTEESMTI-DKNTKIPCKSPPPELTDTAT------------STKRCPKTRPRKE 2251
+A P T+E+ T +K T+ + ++T T T +T PK K+
Sbjct: 931 TTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKK 990
Query: 2252 VKEELSAVERLTQTSGQSTHTHKEPASGDEGIKVLKQRAKKKPNPVEEEPSRRRPRAPKE 2311
+ + +T+ A+ + K K A KKP ++ + R R PK
Sbjct: 991 TITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTK--APKKPTSTKKPKTMPRVRKPKT 1048
Query: 2312 KAQPLEDLAGFTELSETSGHTQESLTAGKATKIPCESPPLEVVDTTASTK 2361
P + + EL+ TS + L + T P ++P ++V+ ++
Sbjct: 1049 TPTPRKMTSTMPELNPTSRIAEAML---QTTTRPNQTPNSKLVEVNPKSE 1095
Score = 97.4 bits (241), Expect = 2e-19
Identities = 266/1125 (23%), Positives = 376/1125 (33%), Gaps = 170/1125 (15%)
Query: 440 PTSESFGGNVFFSAQNAAKQPSDKCSASPPLRRQCIRENGNVAKTPRNTYKMTS-LETKT 498
P ESF V N PS K + P Q I+ + P N K +E++
Sbjct: 98 PDYESFCAEV----HNPTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEE 153
Query: 499 SDTETEPSKTVSTANRSGRSTEFRNIQKLPVESKSEETNTEIVECILKRGQKATLLQQRR 558
E S+ +++ S S+ I+K+ SK+ N E+ + + + K +
Sbjct: 154 ITEEHSVSENQESSSSSSSSSSSSTIRKIK-SSKNSAANRELQKKLKVKDNK------KN 206
Query: 559 EGEMKEIERPFETYKENIELKENDEKMKAMKRSRTWGQKCAPMSDLTDLKSL-------P 611
+ K +P + L D K+ S T K + +T K + P
Sbjct: 207 RTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPP 266
Query: 612 DTELMKDTARGQNLLQTQDHAKAPKSEKGKIT--KMPCQSLQPEPINTPTHTKQQLKAS- 668
+++ K+T+ N T + + + K T K S + T K S
Sbjct: 267 NSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSK 326
Query: 669 -LGKVGVKEELLAVGKFTRTSGE-TTHTHREPAG---DGKSIRTFKESPKQILDPAARVT 723
L K K E G T E T T +EPA + T K +P +PA T
Sbjct: 327 VLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTT 386
Query: 724 GMKKWPRTPKEEAQSLEDLAGFKELFQTPGPSEESMTDEKTTKIACKSPPPESVDTPTST 783
K P TPKE A + + P P+ TTK + P + PT+
Sbjct: 387 --KSAPTTPKEPAPTTT---------KEPAPTTPKEPAPTTTK---EPAPTTTKSAPTTP 432
Query: 784 KQ----WPKRSLRKADVEEEFLALRKLTPSAGKAMLTPKPAGGDEKDIKAFMGTPVQKLD 839
K+ PK+ E ++ TP+ TPK K+ P +
Sbjct: 433 KEPAPTTPKKPAPTTPKEPAPTTPKEPTPT------TPKEPAPTTKE-----PAPTTPKE 481
Query: 840 LAGTLPGSKRQLQTPKEKAQALEDLAGFKELFQTPGHTEELVAAGKTTKIPCDSPQSDPV 899
A T P K TPKE P T A TTK P SP +
Sbjct: 482 PAPTAP-KKPAPTTPKE-----------------PAPTTPKEPAPTTTKEP--SPTTPKE 521
Query: 900 DTPTSTKQRPKRSIRKADVEGELLACRNLMPSAGKAMHTPKPSVGEEKDIIIFVGTPVQK 959
PT+TK P + A + SA P P+ +E TP +
Sbjct: 522 PAPTTTKSAPTTTKEPAPTTTK---------SAPTTPKEPSPTTTKEP----APTTPKEP 568
Query: 960 LDLTENLTGSKRRPQTPKEEAQALEDLTGFKELFQTPGHTEEAVAAGKTTKMPCESSPPE 1019
T K P TPKE P T A TTK P ++P E
Sbjct: 569 APTTP----KKPAPTTPKE-----------------PAPTTPKEPAPTTTKKPAPTTPKE 607
Query: 1020 SADTPTSTRRQPKTPLEKRDVQKELSALKKLTQTSGE----TTHTDKVP-GGEDKSINAF 1074
A T T P TP + E KL T+ E TT + P E+ +
Sbjct: 608 PAPT-TPKETAPTTPKKLTPTTPE-----KLAPTTPEKPAPTTPEELAPTTPEEPTPTTP 661
Query: 1075 RETAKQKLDPAASVTGSKRHPKTKEKAQPLEDLAGLKELFQTPVCTDKPTTHEKTTKIAC 1134
E A AA T + P T ++ P KE T PTT + T
Sbjct: 662 EEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTP----KEPAPTTPKETAPTTPKGTAPTTL 717
Query: 1135 RSQPDPVDTPTSSKPQSKRSLRKVDVEEEFFALRKRTPSA--GKAMHTPK-PAVSGEKNI 1191
+ +P P T KP K E K P+ G A TPK PA +
Sbjct: 718 K-EPAPT---TPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPT----- 768
Query: 1192 YAFMGTPVQKLDLTENLTGSKRRLQTPKEKAQALEDLAGFKELFQTRGHTEESMTNDKTA 1251
TP + T T T KE A KEL T S T+DK A
Sbjct: 769 -----TPKEPAPTTPKGTAP----TTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPA 819
Query: 1252 KVACKSSQPDPDKNPASSKRRLKTSLGKVGVKEELLAVGKLTQTSGETTHTHTEPTGDGK 1311
K + P K PA + + V T T+ E T H P
Sbjct: 820 PTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPT-TTKEPTTIHKSPDESTP 878
Query: 1312 SM------KAFMESPKQI-LDSAASLTGSKRQLRTPKGKSEVPEDLAGFIE-LFQTPSHT 1363
+ KA SPK+ + + + +K ++ T DL E P T
Sbjct: 879 ELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMT 938
Query: 1364 KE-SMTNEKTTKVSYRASQPDLVDTPTSSKPQPKRSLRKADTEEEFLAFRKQTPSAGKAM 1422
KE + T EKTT+ A+ + T T K + K T + K+T + + M
Sbjct: 939 KETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIM 998
Query: 1423 HTPKPAVGEEKDINTFLGTPVQKLDQPGNLPGSNRRLQTRKEKAQALEELTGFRELFQTP 1482
+ P+ + KD T K +P P + T+K K + R+ TP
Sbjct: 999 NKPE-ETAKPKDRATNSKATTPKPQKPTKAP--KKPTSTKKPKT-----MPRVRKPKTTP 1050
Query: 1483 CTDNPTTDEKTTKKILCKSPQSDPADTPTNTKQRPKRSLKKADVE 1527
T K T + +P S A+ T RP ++ VE
Sbjct: 1051 ------TPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVE 1089
Score = 80.5 bits (197), Expect = 2e-14
Identities = 219/1040 (21%), Positives = 330/1040 (31%), Gaps = 154/1040 (14%)
Query: 1620 SCKSPQPDPVK------TPTSSKQRLKISLGKVGVKEEVLPVGKLTQTSGKTTQTHRETA 1673
S K+P P T S K K KV EE+ +++ ++ + ++
Sbjct: 116 SKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSSSSSSS 175
Query: 1674 GDG-KSIKAFKESAK--------QMLDPANYGTGMERWPRTPK-EEAQSLEDLAGFKELF 1723
+ IK+ K SA ++ D T + P+ P +EA S D FK
Sbjct: 176 SSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFK--V 233
Query: 1724 QTPD-----HTEESTTDDKTTKIACKSPPPESMDTPTSTRRRPKTPLGKRDIVEELSALK 1778
TPD H + ST+ TT A P S+ + T + + K VE
Sbjct: 234 TTPDTSTTQHNKVSTSPKITT--AKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTT 291
Query: 1779 QLTQTTHTDKVPGDEDKGINVFRETAKQKLDPAASVTG--SKRQPRTPKGKAQPLEDLAG 1836
QT+ K K +T+ + L P + V + + T KG A L
Sbjct: 292 TNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPA-----LTT 346
Query: 1837 LKELFQTPICTDKPTTHEKTTKIACRSPQPDPVG----TPTIFKPQSKRSLRKADVEEES 1892
KE PTT ++ + P P + TP P + +S E
Sbjct: 347 PKE--------PTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAP 398
Query: 1893 LALRKRTPSVGKAMDTPKPAGGDEKDMKAFMGTPVQKLDLPGNLPGSKRWPQTPKEKAQA 1952
++ P+ K P P E P + P K P TPKE A
Sbjct: 399 TTTKEPAPTTPKE---PAPTTTKEPAPTTTKSAPTTPKE-PAPTTPKKPAPTTPKEPAPT 454
Query: 1953 LEDLAGFKELFQTPGTDKPTTDEKTTKIACKSPQPDPVDTPASTKQRPKRNLRKADVEEE 2012
TP PTT ++ K P P PA T PK+ E
Sbjct: 455 ------------TPKEPTPTTPKEPAPTT-KEPAPTTPKEPAPTA--PKKPAPTTPKEPA 499
Query: 2013 FLALRKRTPSAGK--AMDTPK-PAVSDEKNINTFVETPVQKLDLLGNLPGSKRQPQTPKE 2069
++ P+ K + TPK PA + K+ T + P +K P TPKE
Sbjct: 500 PTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTT--------TKSAPTTPKE 551
Query: 2070 KAEALEDLVGFKELFQTPGHTEESMTDDKITEVSCKSPQPESFKTSRSSKQRLKIPLVKV 2129
+ KE T T K + K P P + K + + P
Sbjct: 552 PSPTTT-----KEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTP- 605
Query: 2130 DMKEEPLAVSKLTRTSGETTQTHTEPTGDSKSIKAFKESPKQILDPAASVTGSRRQLRTR 2189
+EP + + + TT PT K E P + T T
Sbjct: 606 ---KEPAPTTP--KETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTT 660
Query: 2190 KEKARALEDLVDFKELFSAPGHTEESMTIDKNTKIPCKSPPPELTDTA------TSTKRC 2243
E+ P T K P + P E T T+ K
Sbjct: 661 PEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEP 720
Query: 2244 PKTRPRKEVKEELSAVERLTQTSGQSTHTHKEPASGDEGIKVLKQRAKKKPNPVEEEPSR 2303
T P+K +EL+ T KEP S KP P P
Sbjct: 721 APTTPKKPAPKELAPT------------TTKEPTS----------TTCDKPAPTT--PKG 756
Query: 2304 RRPRAPKEKAQPLEDLAGFTELSETSGHTQESLTAGKATKIPCESPPLEVVDTTASTKRH 2363
P PKE A T T+ T + A P + P E+ TT
Sbjct: 757 TAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKE----PAPTTPKKPAPKELAPTT------ 806
Query: 2364 LRTRVQKVQVKEEPSAVKFTQTSGETTDADKEPAGEDKGIKALKESAKQTPAPAASVTGS 2423
T+ ++P+ +T+ TT + P K E+ T + ++ T +
Sbjct: 807 --TKGPTSTTSDKPAPTTPKETA-PTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTT 863
Query: 2424 RRRPRAPRESAQAIEDLAGFKDPAAGHTEESMTDDKTTKIPCKSSPELEDTATSS----- 2478
+ + ++ +L+ P A TTK P + PE+ TA
Sbjct: 864 KEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERD 923
Query: 2479 -KRRPRTRAQKVEVKEELLAVGKLTQTSGETTHTDKEPVGEGKGTKAFK-------QPAK 2530
+ P T ++ +E + T S T T + + T FK A
Sbjct: 924 LRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAP 983
Query: 2531 RKLDAEDVIGSRRQPRAPKEKAQPLEDLASFQELSQTPGHTEELANGAADSFTSAPKQTP 2590
+ + I + P+E A+P + + + + P T APK+
Sbjct: 984 KVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKP-----------QKPTKAPKKPT 1032
Query: 2591 DSGKPLKISRRVLRAPKVEP 2610
+ KP + R +R PK P
Sbjct: 1033 STKKPKTMPR--VRKPKTTP 1050
Score = 66.6 bits (161), Expect = 3e-10
Identities = 229/1059 (21%), Positives = 337/1059 (31%), Gaps = 136/1059 (12%)
Query: 1008 TTKMPCESSPPESADTPT---STRRQPKTP--------LEKRDVQKELSALKKLTQTSGE 1056
T+ + +PP S + T +T+R PK P +E ++ +E S + +S
Sbjct: 111 TSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSS 170
Query: 1057 TTHTDKVPGGEDKSINAFRETAKQKLDPAASVTGSKRHPKTKEKAQP---LEDLAGL--- 1110
++ + + KS A ++L V +K++ +TK+K P + D AG
Sbjct: 171 SSSSSSSTIRKIKSSK--NSAANRELQKKLKVKDNKKN-RTKKKPTPKPPVVDEAGSGLD 227
Query: 1111 KELFQTPVCTDKPTTHEKTTKIACRSQPDPVDTPTSSKPQSKRSLR-KVDVEEEFFALRK 1169
F+ T H K + + P++ S P S S + V +E K
Sbjct: 228 NGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETK 287
Query: 1170 RTPSAGKAMHTPKPAVSGEKNIYAFMGTPVQKLDLTENLTGSKRRLQTPKEKAQALED-- 1227
T + K T EK A ++K ++L + + L P KA+
Sbjct: 288 ETTTTNKQTSTD----GKEKTTSAKETQSIEKTS-AKDLAPTSKVLAKPTPKAETTTKGP 342
Query: 1228 -LAGFKELFQTRGHTEESMTNDKTAKVACKSSQPDPDKNPASSKRRLKTSLGKVGVKEEL 1286
L KE T S T + KS+ P K PA + + + K
Sbjct: 343 ALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTP-KEPAPTTTKSAPTTPK------- 394
Query: 1287 LAVGKLTQTSGETTHTHTEPTGDGKSMKAFMESPKQILDSAASLTGSKRQLRTPKGKSEV 1346
TT PT + + P +A T + TPK +
Sbjct: 395 --------EPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPT 446
Query: 1347 -PEDLAGFIELFQTPSHTKESMTNEK----TTKVSYRASQPDLVDTPTSSKPQPKRSLRK 1401
P++ A TP+ KE K TT + P T +P P
Sbjct: 447 TPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEP 506
Query: 1402 ADTEEEFLAFRKQTPSAGKAMHTPKPAVGEEKDINTFLGTPVQKLDQPGNLPGSNRRLQT 1461
A T ++ +P+ K +PA K T P + T
Sbjct: 507 APTTT-----KEPSPTTPK-----EPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTT 556
Query: 1462 RKEKAQALEELTGFRELFQTPCTDNPTTDEK---TTKKILCKSPQSDPADTPTNTKQ--- 1515
KE A TP PTT +K TT K + +PA PT TK+
Sbjct: 557 TKEPAPT------------TPKEPAPTTPKKPAPTTPKEPAPTTPKEPA--PTTTKKPAP 602
Query: 1516 -RPKRSLKKADVEEEFLAFRKLTPSAGKAMHTPKAAVGEEKDINTFVGTPVEKLDLLGNL 1574
PK E +KLTP+ + + A EK T TP E L
Sbjct: 603 TTPKEPAPTTPKETAPTTPKKLTPTTPEKL----APTTPEKPAPT---TPEE----LAPT 651
Query: 1575 PGSKRRPQTPKEKAKALEDLAGF---KELFQTPGHTEESMTDDKITEVSCKSPQPDPVK- 1630
+ P TP+E A A KE T T + + K P K
Sbjct: 652 TPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKG 711
Query: 1631 -TPTSSKQRLKISLGKVGVKEEVLPVGKLTQTSGKTTQTHRETAGDGKSIKAFKESAKQM 1689
PT+ K+ + K KE K + + T T G + KE A
Sbjct: 712 TAPTTLKEPAPTTPKKPAPKELAPTTTK--EPTSTTCDKPAPTTPKGTAPTTPKEPAPTT 769
Query: 1690 LDPANYGTGMERWPRTPKEEAQSLEDLAGFKELFQTPDHTEESTTDDKTTKIACKSPPPE 1749
T P T KE A + KEL T STT DK K P
Sbjct: 770 PKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPT 829
Query: 1750 SMDTPTST---RRRPKTPLGKRDIVEELSALKQLTQTTHTDKVPGDEDKGINVFRETAKQ 1806
+ P T + P TP E+S + T K P + ++ E +
Sbjct: 830 TPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSA--EPTPK 887
Query: 1807 KLDPAASVTG---SKRQPRTPKGKAQPLEDLAGLKELFQTPICT--------DKPTTHEK 1855
L+ + G +K T +D ++L TP T + TT EK
Sbjct: 888 ALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEK 947
Query: 1856 TTKIACRSPQPDPVGTPTIFKPQSKRSLRKADVEEESLALRKRTPSVGKAMDTPKPAGGD 1915
TT+ + T T K + K + K+T + + M+ P+
Sbjct: 948 TTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEET-AK 1006
Query: 1916 EKDMKAFMGTPVQKLDLPGNLPGSKRWPQTPKEKAQALEDLAGFKELFQTPGTDKPTTDE 1975
KD K P P K+ T K K P KP T
Sbjct: 1007 PKDRATNSKATTPKPQKPTKAP--KKPTSTKKPKTM--------------PRVRKPKTTP 1050
Query: 1976 KTTKIACKSPQPDPVDTPA----STKQRPKRNLRKADVE 2010
K+ P+ +P A T RP + VE
Sbjct: 1051 TPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVE 1089
Score = 50.8 bits (120), Expect = 2e-05
Identities = 99/498 (19%), Positives = 164/498 (32%), Gaps = 53/498 (10%)
Query: 2058 PGSKRQPQTPKEKAEALEDLVGFKELFQTPGHTEESMTDDKITEVSCKSPQPESFKTSRS 2117
P SK+ P P ++ ++ T++ + ++ITE S ES +S S
Sbjct: 114 PSSKKAPP-PSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSSSS 172
Query: 2118 SKQRLKIPLVKVDMKEEPLAVSKLTRTSGETTQTHTEPTGDSKSIKAFKESPKQILDPAA 2177
S I +K S + Q + + K+ K +PK P
Sbjct: 173 SSSSSTIRKIK----------SSKNSAANRELQKKLKVKDNKKNRTKKKPTPKP---PVV 219
Query: 2178 SVTGSRRQLRTRKEKARALEDLVDFKELFSAPGHTEESM--TIDKNTKIPCKSPPPELTD 2235
GS D DFK T+ + T K T +P P L
Sbjct: 220 DEAGSGL-------------DNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPP 266
Query: 2236 TATSTKRCPKTRPRKEVKEELSAVERLTQTSGQSTHTH-KEPASGDEGIKVLKQRAKKKP 2294
+ ++K T V +E + + T T+ + T T KE + + + +++ + K
Sbjct: 267 NSDTSKETSLT-----VNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDL 321
Query: 2295 NPVEEEPSRRRPRAPKEKAQPLEDLAGFTELSETSGHTQESLTAGKATKIPCESPPLEVV 2354
P + ++ P+A P T E + T + A+ P E P +
Sbjct: 322 APTSKVLAKPTPKAETTTKGP-----ALTTPKEPTPTTPKE----PASTTPKEPTPTTIK 372
Query: 2355 DTTASTKRHLRTRVQKVQVKEEPSAVKFTQTSGETTDADKEPAGEDKGIKALKESAKQTP 2414
+ K T + + A T+ TT + P + +SA TP
Sbjct: 373 SAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTP 432
Query: 2415 APAASVTGSRRRPRAPRESAQAIEDLAGFKDPAAGHTEESMTDDKTTKIPCKSSPELEDT 2474
A T + P P+E A K+P +E TTK P ++P+ E
Sbjct: 433 KEPAPTTPKKPAPTTPKEPAPTTP-----KEPTPTTPKEPA---PTTKEPAPTTPK-EPA 483
Query: 2475 ATSSKRRPRTRAQKVEVKEELLAVGKLTQTSGETTHTDKEPVGEGKGTKAFKQPAKRKLD 2534
T+ K+ T ++ T+ TT + P K+PA
Sbjct: 484 PTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTK 543
Query: 2535 AEDVIGSRRQPRAPKEKA 2552
+ P KE A
Sbjct: 544 SAPTTPKEPSPTTTKEPA 561
Score = 38.9 bits (89), Expect = 0.075
Identities = 102/461 (22%), Positives = 150/461 (32%), Gaps = 88/461 (19%)
Query: 634 APKSEKGKITKMPCQSLQPEPI-NTPTHTKQQLKASLGKVGVKEELLAVGKFTRTSGETT 692
APK TK P + +P TP T KE K G
Sbjct: 729 APKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPK-----GTAP 783
Query: 693 HTHREPAGDGKSIRTFKESPKQILDPAAR----VTGMKKWPRTPKEEAQSLEDLAGFKEL 748
T +EPA K +PK++ + T K P TPKE A +
Sbjct: 784 TTLKEPAPTTPK----KPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTP-------- 831
Query: 749 FQTPGPSEESMTDEKTTKIACKSPPPES--VDTPTSTKQWPKRSLRKADVEEEFLALRKL 806
+ P P+ T +K ++PPP + V TPT+TK+ ++ K+ E
Sbjct: 832 -KEPAPT----TPKKPAPTTPETPPPTTSEVSTPTTTKE--PTTIHKSPDES-------- 876
Query: 807 TPSAGKAMLTPKPAGGDEKDIKAFMGTPVQKLDLAGTLPGSKRQLQTPKEKAQALEDLAG 866
TP A TPK K+ G P K A T E +D
Sbjct: 877 TPELS-AEPTPKALENSPKE----PGVPTTKTPAA-----------TKPEMTTTAKDKTT 920
Query: 867 FKELFQTPGHTEELVAAGKTTKIPCDSPQSDPVDTPTSTKQRPKRSIRKADVEGELLACR 926
++L TP E AA K TK +T T+T++ + I + +
Sbjct: 921 ERDLRTTP---ETTTAAPKMTK-----------ETATTTEKTTESKITATTTQVTSTTTQ 966
Query: 927 NLMPSAGKAMHTPKPSVGEEKDIIIFVGTPVQKLDLTENLTGSKRRPQTPKEEAQALEDL 986
+ P + T T K+ T+ + P+E A+ +
Sbjct: 967 DTTPFKITTLKTT---------------TLAPKVTTTKKTITTTEIMNKPEETAKPKDRA 1011
Query: 987 TGFKELFQTPGHTEEAVAAGKTTKMPCESSPPESADTPTSTRRQPKTPLEKRDVQKELSA 1046
T K P +A +TK P T + R+ T E + A
Sbjct: 1012 TNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEA 1071
Query: 1047 LKKLTQTSGETTHTDKV---PGGEDKSINAFRETAKQKLDP 1084
+ + T +T ++ V P ED A ET L P
Sbjct: 1072 MLQTTTRPNQTPNSKLVEVNPKSEDAG-GAEGETPHMLLRP 1111
Score = 35.0 bits (79), Expect = 1.1
Identities = 57/264 (21%), Positives = 97/264 (36%), Gaps = 27/264 (10%)
Query: 2636 FKRGGGKDGSVTGTKRLRCMPAPEEIVEEL------PASKKQRVAPRARGKSSEPVVIMK 2689
F+RG D K +C P E E+ P+SKK AP G S K
Sbjct: 78 FERGRECDCDAQCKKYDKCCPDYESFCAEVHNPTSPPSSKK---APPPSGASQTIKSTTK 134
Query: 2690 RSLRTSAKR-----IEPAEELNSNDMKTNKEEHKLQDSVPENKGISLRSRRQNKTEAEQQ 2744
RS + K+ IE E + + N+E S + ++R + +K A +
Sbjct: 135 RSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSSSS--SSSSSTIRKIKSSKNSAANR 192
Query: 2745 ITEVFVLAERIEINRNEKKPMKTSPEMDIQNP--DDGARK-PIPRDKVTENKRCLRSARQ 2801
+ + + + NR +KKP P +D D+G K P T++ + S +
Sbjct: 193 ELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKI 252
Query: 2802 NESS----QPKVAEESGGQKSAKVLMQN----QKGKGEAGNSDSMCLRSRKTKSQPAAST 2853
+ +P + S K + + + + N + KT S +
Sbjct: 253 TTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQS 312
Query: 2854 LESKSVQRVTRSVKRCAENPKKAE 2877
+E S + + + K A+ KAE
Sbjct: 313 IEKTSAKDLAPTSKVLAKPTPKAE 336
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 93.6 bits (231), Expect = 3e-18
Identities = 220/978 (22%), Positives = 320/978 (32%), Gaps = 127/978 (12%)
Query: 1420 KAMHTPKPAVGEEKDINTFLGTPVQKLDQPGNLPGSNRRLQTRKEKAQALEELTGFRELF 1479
K TPKP V +E G+ + D P ++ T+ K ++T + +
Sbjct: 75 KKKPTPKPPVVDEA------GSGLDNGDFKVTTPDTST---TQHNKVSTSPKITTAKPIN 125
Query: 1480 QTPCTDNPTTDEKTTKKILCKSPQSDPADTPTNTKQRPKRSLKKADVEEEFLAFRK---- 1535
P + K T + K + +T T KQ +K +E + K
Sbjct: 126 PRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAK 185
Query: 1536 -LTPSAGK-AMHTPKAAVGEEKDINTFVGTPVEKLDLLGNLPGSKRRPQTPKEKAKALED 1593
L P++ A TPKA + T TP E P TPKE A
Sbjct: 186 DLAPTSKVLAKPTPKAETTTKGPALT---TPKEPT------------PTTPKEPAST--- 227
Query: 1594 LAGFKELFQTPGHTEESMTDDKITEVSCKSPQPDPVKT-PTSSKQRLKISLGKVGVKEEV 1652
TP E + T K + K P P K+ PT+ K+ + +
Sbjct: 228 ---------TP--KEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPK 276
Query: 1653 LPVGKLTQTSGKTTQTHRETAGDGKSIKAFKESAKQMLDPANYGTGMERWPRTPKEEAQS 1712
P T+ TT T + K+ A T E P TPKE A +
Sbjct: 277 EPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPT 336
Query: 1713 LEDLAGFKELFQTPDHTEESTTDDKTTKIACKSPPPESMDTPTSTRRRPKTPLGKRDIVE 1772
KE T T K K P P + P T + +P + E
Sbjct: 337 T------KEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPK---E 387
Query: 1773 ELSALKQLTQTTHTDKVPGDEDKGINVFRETAKQKLDPAASVTGSKRQPRTPKGKAQPLE 1832
+ TT + P +E + A T + P TPK A
Sbjct: 388 PAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTP 447
Query: 1833 DLAGLKELFQTPICTDKPTTHEKTTKIACRSPQPDPVGTPTIFKPQSKRSLRKADVEEES 1892
KE T PTT +K + P P TP P + + L E+
Sbjct: 448 -----KEPAPTTPKEPAPTTTKKPAPTTPKEPAPT---TPKETAPTTPKKLTPTTPEK-- 497
Query: 1893 LALRKRTPSVGKAMDTPKPAGGDEKDMKAFMGTPVQKLDLPGNLPGSKRWPQTPKEKAQA 1952
L TP + P P +E + P P TPKE A
Sbjct: 498 --LAPTTP------EKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPT 549
Query: 1953 LEDLAGFKELFQTPGTDKPTTDEKTTKIACKSPQPDPVDTPAST---KQRPKRNLRKADV 2009
+ TP PTT ++T K P + PA T K PK
Sbjct: 550 TPK----EPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTK 605
Query: 2010 EEEFLALRKRTPSA--GKAMDTPK-PAVSDEKNINTFVETPVQKLDLLGNLPGSKRQPQ- 2065
E K P+ G A TPK PA + K TP G P + ++P
Sbjct: 606 EPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKE--PAPTTPK------GTAPTTLKEPAP 657
Query: 2066 -TPKEKAEALEDLVGFKELFQTPGHTEESMTDDKITEVSCKSPQPESFKTSRSSKQRLKI 2124
TPK+ A KEL T S T DK + K P + K + +
Sbjct: 658 TTPKKPAP--------KELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPA 709
Query: 2125 PLVKVDMKEEPLAVSKLTRTSGETTQTHTEPTGDSKSI------KAFKESPKQILDPAAS 2178
P VS T T E T H P + + KA + SPK+ P
Sbjct: 710 PTTPETPPPTTSEVSTPTTTK-EPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTK 768
Query: 2179 VTGSRRQLRTRKEKARALE-DLVDFKELFSA-PGHTEESMTI-DKNTKIPCKSPPPELTD 2235
+ + T K + E DL E +A P T+E+ T +K T+ + ++T
Sbjct: 769 TPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTS 828
Query: 2236 TAT------------STKRCPKTRPRKEVKEELSAVERLTQTSGQSTHTHKEPASGDEGI 2283
T T +T PK K+ + + +T+ A+ +
Sbjct: 829 TTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQ 888
Query: 2284 KVLKQRAKKKPNPVEEEPSRRRPRAPKEKAQPLEDLAGFTELSETSGHTQESLTAGKATK 2343
K K A KKP ++ + R R PK P + + EL+ TS + L + T
Sbjct: 889 KPTK--APKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAML---QTTT 943
Query: 2344 IPCESPPLEVVDTTASTK 2361
P ++P ++V+ ++
Sbjct: 944 RPNQTPNSKLVEVNPKSE 961
Score = 87.8 bits (216), Expect = 1e-16
Identities = 245/1025 (23%), Positives = 342/1025 (33%), Gaps = 137/1025 (13%)
Query: 553 LLQQRREGEMKEIERPFETYKENIELKENDEKMKAMKRSRTWGQKCAPMSD----LTDLK 608
++QQ E+ R FE+++ E + + K K + CA + D T K
Sbjct: 18 VIQQVSSQELSCKGRCFESFERGRECDCDAQCKKYDKCCPDYESFCAEVKDNKKNRTKKK 77
Query: 609 SLPDTELMKDTARGQNL---------LQTQDHAKAPKSEKGKITKMPCQSLQPEPINTPT 659
P ++ + G + T H K S K K + P P P
Sbjct: 78 PTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAK----PINPRPSLPPN 133
Query: 660 HTKQQLKASLGKVGVKEELLAVGKFTRT-SGETTHTHREPAGDGKSIRTFKESPKQILDP 718
KE L V K T + ETT T+++ + DGK T + + I
Sbjct: 134 SDTS-----------KETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKT 182
Query: 719 AAR---VTGMKKWPRTPKEEAQSL-EDLAGFKELFQTPGPSEESMTDEKTTKIACKSPPP 774
+A+ T TPK E + L KE T S T ++ T KS P
Sbjct: 183 SAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPT 242
Query: 775 ESVD-TPTSTKQWPKRSLRKADVEEEFLALRKLTPSAGKAMLTPKPAGGDEKDIKAFMGT 833
+ PT+TK P A + A TP T +PA K
Sbjct: 243 TPKEPAPTTTKSAPTTPKEPAPTTTKEPA--PTTPKEPAPTTTKEPAPTTTK------SA 294
Query: 834 PVQKLDLAGTLPGSKRQLQTPKEKAQALEDLAGFKELFQTPGHTEELVAAGKTTKIPCDS 893
P + A T P K TPKE A KE TP +E TTK P +
Sbjct: 295 PTTPKEPAPTTP-KKPAPTTPKEPAPTTP-----KE--PTPTTPKE---PAPTTKEPAPT 343
Query: 894 PQSDPVDTPTSTKQRPKRSIRKADVEGELLACRNLMPSAGKAMHTPKPSVGEEKDIIIFV 953
+P T PK+ E + P+ K P P+ +E
Sbjct: 344 TPKEPAPT------APKKPAPTTPKEPAPTTPKEPAPTTTK---EPSPTTPKEPAPTTTK 394
Query: 954 GTPVQKLDLTENLTGSKRRPQTPKEEAQALEDLTGFKELFQTPGHTEEAVAAGKTTKMPC 1013
P + T +K P TPKE + T KE P T A T K P
Sbjct: 395 SAPTTTKEPAP--TTTKSAPTTPKEPSP-----TTTKE----PAPTTPKEPAPTTPKKPA 443
Query: 1014 ESSPPESADT------PTSTRR----QPKTPLEKRDVQKELSALKKLTQTSGE----TTH 1059
++P E A T PT+T++ PK P + + KKLT T+ E TT
Sbjct: 444 PTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTP 503
Query: 1060 TDKVPGGEDKSINAFRE----TAKQKLDPAASVTGSKRHPKTKEKAQPLEDLAGL-KELF 1114
P ++ E T ++ P + PK P E KE
Sbjct: 504 EKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPA 563
Query: 1115 QTPVCTDKPTTHEKTTKIACRSQPDPVDTPTSSKPQSKRSLRKVDVEEEFFALRKRTPSA 1174
T PTT + T + +P P T KP K E K P+
Sbjct: 564 PTTPKETAPTTPKGTAPTTLK-EPAPT---TPKKPAPKELAPTTTKEPTSTTCDKPAPTT 619
Query: 1175 --GKAMHTPK-PAVSGEKNIYAFMGTPVQKLDLTENLTGSKRRLQTPKEKAQALEDLAGF 1231
G A TPK PA + TP + T T T KE A
Sbjct: 620 PKGTAPTTPKEPAPT----------TPKEPAPTTPKGTAP----TTLKEPAPTTPKKPAP 665
Query: 1232 KELFQTRGHTEESMTNDKTAKVACKSSQPDPDKNPASSKRRLKTSLGKVGVKEELLAVGK 1291
KEL T S T+DK A K + P K PA + + V
Sbjct: 666 KELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVST 725
Query: 1292 LTQTSGETTHTHTEPTGDGKSM------KAFMESPKQI-LDSAASLTGSKRQLRTPKGKS 1344
T T+ E T H P + KA SPK+ + + + +K ++ T
Sbjct: 726 PT-TTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDK 784
Query: 1345 EVPEDLAGFIE-LFQTPSHTKE-SMTNEKTTKVSYRASQPDLVDTPTSSKPQPKRSLRKA 1402
DL E P TKE + T EKTT+ A+ + T T K + K
Sbjct: 785 TTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKT 844
Query: 1403 DTEEEFLAFRKQTPSAGKAMHTPKPAVGEEKDINTFLGTPVQKLDQPGNLPGSNRRLQTR 1462
T + K+T + + M+ P+ + KD T K +P P + T+
Sbjct: 845 TTLAPKVTTTKKTITTTEIMNKPE-ETAKPKDRATNSKATTPKPQKPTKAP--KKPTSTK 901
Query: 1463 KEKAQALEELTGFRELFQTPCTDNPTTDEKTTKKILCKSPQSDPADTPTNTKQRPKRSLK 1522
K K + R+ TP T K T + +P S A+ T RP ++
Sbjct: 902 KPKT-----MPRVRKPKTTP------TPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPN 950
Query: 1523 KADVE 1527
VE
Sbjct: 951 SKLVE 955
Score = 78.2 bits (191), Expect = 1e-13
Identities = 201/943 (21%), Positives = 296/943 (31%), Gaps = 142/943 (15%)
Query: 1705 TPK----EEAQSLEDLAGFKELFQTPD-----HTEESTTDDKTTKIACKSPPPESMDTPT 1755
TPK +EA S D FK TPD H + ST+ TT A P S+ +
Sbjct: 79 TPKPPVVDEAGSGLDNGDFK--VTTPDTSTTQHNKVSTSPKITT--AKPINPRPSLPPNS 134
Query: 1756 STRRRPKTPLGKRDIVEELSALKQLTQTTHTDKVPGDEDKGINVFRETAKQKLDPAASVT 1815
T + + K VE QT+ K K +T+ + L P + V
Sbjct: 135 DTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVL 194
Query: 1816 G--SKRQPRTPKGKAQPLEDLAGLKELFQTPICTDKPTTHEKTTKIACRSPQPDPVG--- 1870
+ + T KG A L KE PTT ++ + P P +
Sbjct: 195 AKPTPKAETTTKGPA-----LTTPKE--------PTPTTPKEPASTTPKEPTPTTIKSAP 241
Query: 1871 -TPTIFKPQSKRSLRKADVEEESLALRKRTPSVGKAMDTPKPAGGDEKDMKAFMGTPVQK 1929
TP P + +S E ++ P+ K P P E P
Sbjct: 242 TTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKE---PAPTTTKEPAPTTTKSAPTTP 298
Query: 1930 LDLPGNLPGSKRWPQTPKEKAQALEDLAGFKELFQTPGTDKPTTDEKTTKIACKSPQPDP 1989
+ P K P TPKE A TP PTT ++ K P P
Sbjct: 299 KE-PAPTTPKKPAPTTPKEPAPT------------TPKEPTPTTPKEPAPTT-KEPAPTT 344
Query: 1990 VDTPASTKQRPKRNLRKADVEEEFLALRKRTPSAGK--AMDTPK-PAVSDEKNINTFVET 2046
PA T PK+ E ++ P+ K + TPK PA + K+ T +
Sbjct: 345 PKEPAPTA--PKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKE 402
Query: 2047 PVQKLDLLGNLPGSKRQPQTPKEKAEALEDLVGFKELFQTPGHTEESMTDDKITEVSCKS 2106
P +K P TPKE + KE T T K + K
Sbjct: 403 PAPTT--------TKSAPTTPKEPSPTTT-----KEPAPTTPKEPAPTTPKKPAPTTPKE 449
Query: 2107 PQPESFKTSRSSKQRLKIPLVKVDMKEEPLAVSKLTRTSGETTQTHTEPTGDSKSIKAFK 2166
P P + K + + P +EP + + + TT PT K
Sbjct: 450 PAPTTPKEPAPTTTKKPAPTTP----KEPAPTTP--KETAPTTPKKLTPTTPEKLAPTTP 503
Query: 2167 ESPKQILDPAASVTGSRRQLRTRKEKARALEDLVDFKELFSAPGHTEESMTIDKNTKIPC 2226
E P + T T E+ P T K P
Sbjct: 504 EKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPA 563
Query: 2227 KSPPPELTDTA------TSTKRCPKTRPRKEVKEELSAVERLTQTSGQSTHTHKEPASGD 2280
+ P E T T+ K T P+K +EL+ T KEP S
Sbjct: 564 PTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPT------------TTKEPTS-- 609
Query: 2281 EGIKVLKQRAKKKPNPVEEEPSRRRPRAPKEKAQPLEDLAGFTELSETSGHTQESLTAGK 2340
KP P P P PKE A T T+ T +
Sbjct: 610 --------TTCDKPAPTT--PKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKE----P 655
Query: 2341 ATKIPCESPPLEVVDTTASTKRHLRTRVQKVQVKEEPSAVKFTQTSGETTDADKEPAGED 2400
A P + P E+ TT T+ ++P+ +T+ TT + P
Sbjct: 656 APTTPKKPAPKELAPTT--------TKGPTSTTSDKPAPTTPKETA-PTTPKEPAPTTPK 706
Query: 2401 KGIKALKESAKQTPAPAASVTGSRRRPRAPRESAQAIEDLAGFKDPAAGHTEESMTDDKT 2460
K E+ T + ++ T ++ + ++ +L+ P A T
Sbjct: 707 KPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPT 766
Query: 2461 TKIPCKSSPELEDTATSS------KRRPRTRAQKVEVKEELLAVGKLTQTSGETTHTDKE 2514
TK P + PE+ TA + P T ++ +E + T S T T +
Sbjct: 767 TKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQV 826
Query: 2515 PVGEGKGTKAFK-------QPAKRKLDAEDVIGSRRQPRAPKEKAQPLEDLASFQELSQT 2567
+ T FK A + + I + P+E A+P + + + +
Sbjct: 827 TSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPK 886
Query: 2568 PGHTEELANGAADSFTSAPKQTPDSGKPLKISRRVLRAPKVEP 2610
P T APK+ + KP + R +R PK P
Sbjct: 887 P-----------QKPTKAPKKPTSTKKPKTMPR--VRKPKTTP 916
Score = 66.2 bits (160), Expect = 4e-10
Identities = 189/834 (22%), Positives = 263/834 (31%), Gaps = 139/834 (16%)
Query: 878 EELVAAGKTTKIPCDSPQSDPVDTPTSTKQRPKRSIRKADVEGELLACRNLMPSA----- 932
E + K T + ++ ++ + TST + K + K E + ++L P++
Sbjct: 139 ETSLTVNKETTV--ETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAK 196
Query: 933 ----------GKAMHTPK-PSVGEEKDIIIFVGTPVQKLDLTENLTGSKRRPQTPKEEAQ 981
G A+ TPK P+ K+ P T K P TPKE A
Sbjct: 197 PTPKAETTTKGPALTTPKEPTPTTPKE-------PASTTPKEPTPTTIKSAPTTPKEPAP 249
Query: 982 ALEDLTGFKELFQTPGHTEEAVAAGKTTKMPCESSPPESADT------PTSTRRQPKTPL 1035
T K TP A TTK P ++P E A T PT+T+ P TP
Sbjct: 250 -----TTTKSAPTTPKEP-----APTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPK 299
Query: 1036 EKRDVQKELSALKKLTQTSGETTHTDKVPGGEDKSINAFRETAKQKLDPAASVTGSKRHP 1095
E + A + TT + P + +E A A K P
Sbjct: 300 EPAPTTPKKPA-PTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAP 358
Query: 1096 KTKEKAQPLEDLAGLKELFQTPVCTDKPTTHEK----TTKIACRSQPDPVDTPTSSKPQS 1151
T ++ P KE T PTT ++ TTK A + +P T T S P +
Sbjct: 359 TTPKEPAPTTP----KEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTT 414
Query: 1152 KRSLRKVDVEEEFFALRKRTPSAGKAMHTPKPAVSGEKNIYAFMGTPVQKLDLTENLTGS 1211
+ +E TP KPA + K TP + T
Sbjct: 415 PKEPSPTTTKEP----APTTPKEPAPTTPKKPAPTTPKE--PAPTTPKEPAPTTT----K 464
Query: 1212 KRRLQTPKEKAQALEDLAGFKELFQTRGHTEESMTNDKTAKVACKSSQPDPDKN--PASS 1269
K TPKE A KE T T +K A + P + P +
Sbjct: 465 KPAPTTPKEPAPTTP-----KETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTP 519
Query: 1270 KRRLKTSLGKVGVKEELLAVGKLTQTSGETTHTHTEPTGDGKSMKAFMESPKQILDSAAS 1329
+ T+ + A + TT PT + + +
Sbjct: 520 EEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTA 579
Query: 1330 LTGSKRQLRTPKGKSEVPEDLAGFIELFQTPSHTKE--SMTNEKTTKVSYRASQPDLVDT 1387
T K T K P++LA P+ TKE S T +K + + + P
Sbjct: 580 PTTLKEPAPTTP-KKPAPKELA--------PTTTKEPTSTTCDKPAPTTPKGTAP----- 625
Query: 1388 PTSSKPQPKRSLRKADTEEEFLAFRKQTPSAGKAMHTPKPAVGEEKDINTFLGTPVQKLD 1447
T +P P A T + A T A TPK +E T G D
Sbjct: 626 TTPKEPAPTTPKEPAPTTPKGTA---PTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSD 682
Query: 1448 QPGNLPGSNRRLQTRKEKAQALEELTGFRELFQTPCTDNPTTDEKTTKKILCKSPQSDPA 1507
+P T KE A TP PTT E P +
Sbjct: 683 KPAPTTPKETAPTTPKEPAPT------------TPKKPAPTTPE-------TPPPTTSEV 723
Query: 1508 DTPTNTKQRPKRSLKKADVEEEFLAFRKLTPSAGKAMHTPKAAVGEEKDINTFVGTPVEK 1567
TPT TK+ P K D + TP A TPKA K+ G P K
Sbjct: 724 STPTTTKE-PTTIHKSPD---------ESTPEL-SAEPTPKALENSPKE----PGVPTTK 768
Query: 1568 LDLLGNLPGSKRRPQTPKEKAKALEDLAGFKELFQTPGHT--------EESMTDDKITEV 1619
P + + T K K E ++L TP T E + T +K TE
Sbjct: 769 ------TPAATKPEMTTTAKDKTTE-----RDLRTTPETTTAAPKMTKETATTTEKTTES 817
Query: 1620 SCKSPQPDPVKTPTSSKQRLKISLGKVGVKEEVLPVGKLTQTSGKTTQTHRETA 1673
+ T T KI+ K + K T T+ + ETA
Sbjct: 818 KITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETA 871
Score = 55.8 bits (133), Expect = 6e-07
Identities = 212/970 (21%), Positives = 302/970 (31%), Gaps = 123/970 (12%)
Query: 1086 ASVTGSKRHPKTKEKAQP---LEDLAGL---KELFQTPVCTDKPTTHEKTTKIACRSQPD 1139
A V +K++ +TK+K P + D AG F+ T H K + +
Sbjct: 64 AEVKDNKKN-RTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAK 122
Query: 1140 PVDTPTSSKPQSKRSLR-KVDVEEEFFALRKRTPSAGKAMHTPKPAVSGEKNIYAFMGTP 1198
P++ S P S S + V +E K T + K T EK A
Sbjct: 123 PINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTD----GKEKTTSAKETQS 178
Query: 1199 VQKLDLTENLTGSKRRLQTPKEKAQALED---LAGFKELFQTRGHTEESMTNDKTAKVAC 1255
++K ++L + + L P KA+ L KE T S T +
Sbjct: 179 IEKTS-AKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTI 237
Query: 1256 KSSQPDPDKNPASSKRRLKTSLGKVGVKEELLAVGKLTQTSGETTHTHTEPTGDGKSMKA 1315
KS+ P K PA + + + K TT PT +
Sbjct: 238 KSAPTTP-KEPAPTTTKSAPTTPK---------------EPAPTTTKEPAPTTPKEPAPT 281
Query: 1316 FMESPKQILDSAASLTGSKRQLRTPKGKSEV-PEDLAGFIELFQTPSHTKESMTNEK--- 1371
+ P +A T + TPK + P++ A TP+ KE K
Sbjct: 282 TTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPA 341
Query: 1372 -TTKVSYRASQPDLVDTPTSSKPQPKRSLRKADTEEEFLAFRKQTPSAGKAMHTPKPAVG 1430
TT + P T +P P A T ++ +P+ K +PA
Sbjct: 342 PTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTT-----KEPSPTTPK-----EPAPT 391
Query: 1431 EEKDINTFLGTPVQKLDQPGNLPGSNRRLQTRKEKAQALEELTGFRELFQTPCTDNPTTD 1490
K T P + T KE A TP PTT
Sbjct: 392 TTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPT------------TPKEPAPTTP 439
Query: 1491 EK---TTKKILCKSPQSDPADTPTNTKQ----RPKRSLKKADVEEEFLAFRKLTPSAGKA 1543
+K TT K + +PA PT TK+ PK E +KLTP+ +
Sbjct: 440 KKPAPTTPKEPAPTTPKEPA--PTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEK 497
Query: 1544 MHTPKAAVGEEKDINTFVGTPVEKLDLLGNLPGSKRRPQTPKEKAKALEDLAGF---KEL 1600
+ A EK T TP E L + P TP+E A A KE
Sbjct: 498 L----APTTPEKPAPT---TPEE----LAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEP 546
Query: 1601 FQTPGHTEESMTDDKITEVSCKSPQPDPVK--TPTSSKQRLKISLGKVGVKEEVLPVGKL 1658
T T + + K P K PT+ K+ + K KE K
Sbjct: 547 APTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTK- 605
Query: 1659 TQTSGKTTQTHRETAGDGKSIKAFKESAKQMLDPANYGTGMERWPRTPKEEAQSLEDLAG 1718
+ + T T G + KE A T P T KE A +
Sbjct: 606 -EPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPA 664
Query: 1719 FKELFQTPDHTEESTTDDKTTKIACKSPPPESMDTPTST---RRRPKTPLGKRDIVEELS 1775
KEL T STT DK K P + P T + P TP E+S
Sbjct: 665 PKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVS 724
Query: 1776 ALKQLTQTTHTDKVPGDEDKGINVFRETAKQKLDPAASVTG---SKRQPRTPKGKAQPLE 1832
+ T K P + ++ E + L+ + G +K T +
Sbjct: 725 TPTTTKEPTTIHKSPDESTPELSA--EPTPKALENSPKEPGVPTTKTPAATKPEMTTTAK 782
Query: 1833 DLAGLKELFQTPICT--------DKPTTHEKTTKIACRSPQPDPVGTPTIFKPQSKRSLR 1884
D ++L TP T + TT EKTT+ + T T K +
Sbjct: 783 DKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTL 842
Query: 1885 KADVEEESLALRKRTPSVGKAMDTPKPAGGDEKDMKAFMGTPVQKLDLPGNLPGSKRWPQ 1944
K + K+T + + M+ P+ KD K P P K+
Sbjct: 843 KTTTLAPKVTTTKKTITTTEIMNKPEET-AKPKDRATNSKATTPKPQKPTKAP--KKPTS 899
Query: 1945 TPKEKAQALEDLAGFKELFQTPGTDKPTTDEKTTKIACKSPQPDPVDTPA----STKQRP 2000
T K K P KP T K+ P+ +P A T RP
Sbjct: 900 TKKPKTM--------------PRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRP 945
Query: 2001 KRNLRKADVE 2010
+ VE
Sbjct: 946 NQTPNSKLVE 955
Score = 38.9 bits (89), Expect = 0.075
Identities = 102/461 (22%), Positives = 150/461 (32%), Gaps = 88/461 (19%)
Query: 634 APKSEKGKITKMPCQSLQPEPI-NTPTHTKQQLKASLGKVGVKEELLAVGKFTRTSGETT 692
APK TK P + +P TP T KE K G
Sbjct: 595 APKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPK-----GTAP 649
Query: 693 HTHREPAGDGKSIRTFKESPKQILDPAAR----VTGMKKWPRTPKEEAQSLEDLAGFKEL 748
T +EPA K +PK++ + T K P TPKE A +
Sbjct: 650 TTLKEPAPTTPK----KPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTP-------- 697
Query: 749 FQTPGPSEESMTDEKTTKIACKSPPPES--VDTPTSTKQWPKRSLRKADVEEEFLALRKL 806
+ P P+ T +K ++PPP + V TPT+TK+ ++ K+ E
Sbjct: 698 -KEPAPT----TPKKPAPTTPETPPPTTSEVSTPTTTKE--PTTIHKSPDES-------- 742
Query: 807 TPSAGKAMLTPKPAGGDEKDIKAFMGTPVQKLDLAGTLPGSKRQLQTPKEKAQALEDLAG 866
TP A TPK K+ G P K A T E +D
Sbjct: 743 TPELS-AEPTPKALENSPKE----PGVPTTKTPAA-----------TKPEMTTTAKDKTT 786
Query: 867 FKELFQTPGHTEELVAAGKTTKIPCDSPQSDPVDTPTSTKQRPKRSIRKADVEGELLACR 926
++L TP E AA K TK +T T+T++ + I + +
Sbjct: 787 ERDLRTTP---ETTTAAPKMTK-----------ETATTTEKTTESKITATTTQVTSTTTQ 832
Query: 927 NLMPSAGKAMHTPKPSVGEEKDIIIFVGTPVQKLDLTENLTGSKRRPQTPKEEAQALEDL 986
+ P + T T K+ T+ + P+E A+ +
Sbjct: 833 DTTPFKITTLKTT---------------TLAPKVTTTKKTITTTEIMNKPEETAKPKDRA 877
Query: 987 TGFKELFQTPGHTEEAVAAGKTTKMPCESSPPESADTPTSTRRQPKTPLEKRDVQKELSA 1046
T K P +A +TK P T + R+ T E + A
Sbjct: 878 TNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEA 937
Query: 1047 LKKLTQTSGETTHTDKV---PGGEDKSINAFRETAKQKLDP 1084
+ + T +T ++ V P ED A ET L P
Sbjct: 938 MLQTTTRPNQTPNSKLVEVNPKSEDAG-GAEGETPHMLLRP 977
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 93.6 bits (231), Expect = 3e-18
Identities = 220/978 (22%), Positives = 320/978 (32%), Gaps = 127/978 (12%)
Query: 1420 KAMHTPKPAVGEEKDINTFLGTPVQKLDQPGNLPGSNRRLQTRKEKAQALEELTGFRELF 1479
K TPKP V +E G+ + D P ++ T+ K ++T + +
Sbjct: 116 KKKPTPKPPVVDEA------GSGLDNGDFKVTTPDTST---TQHNKVSTSPKITTAKPIN 166
Query: 1480 QTPCTDNPTTDEKTTKKILCKSPQSDPADTPTNTKQRPKRSLKKADVEEEFLAFRK---- 1535
P + K T + K + +T T KQ +K +E + K
Sbjct: 167 PRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAK 226
Query: 1536 -LTPSAGK-AMHTPKAAVGEEKDINTFVGTPVEKLDLLGNLPGSKRRPQTPKEKAKALED 1593
L P++ A TPKA + T TP E P TPKE A
Sbjct: 227 DLAPTSKVLAKPTPKAETTTKGPALT---TPKEPT------------PTTPKEPAST--- 268
Query: 1594 LAGFKELFQTPGHTEESMTDDKITEVSCKSPQPDPVKT-PTSSKQRLKISLGKVGVKEEV 1652
TP E + T K + K P P K+ PT+ K+ + +
Sbjct: 269 ---------TP--KEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPK 317
Query: 1653 LPVGKLTQTSGKTTQTHRETAGDGKSIKAFKESAKQMLDPANYGTGMERWPRTPKEEAQS 1712
P T+ TT T + K+ A T E P TPKE A +
Sbjct: 318 EPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPT 377
Query: 1713 LEDLAGFKELFQTPDHTEESTTDDKTTKIACKSPPPESMDTPTSTRRRPKTPLGKRDIVE 1772
KE T T K K P P + P T + +P + E
Sbjct: 378 T------KEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPK---E 428
Query: 1773 ELSALKQLTQTTHTDKVPGDEDKGINVFRETAKQKLDPAASVTGSKRQPRTPKGKAQPLE 1832
+ TT + P +E + A T + P TPK A
Sbjct: 429 PAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTP 488
Query: 1833 DLAGLKELFQTPICTDKPTTHEKTTKIACRSPQPDPVGTPTIFKPQSKRSLRKADVEEES 1892
KE T PTT +K + P P TP P + + L E+
Sbjct: 489 -----KEPAPTTPKEPAPTTTKKPAPTTPKEPAPT---TPKETAPTTPKKLTPTTPEK-- 538
Query: 1893 LALRKRTPSVGKAMDTPKPAGGDEKDMKAFMGTPVQKLDLPGNLPGSKRWPQTPKEKAQA 1952
L TP + P P +E + P P TPKE A
Sbjct: 539 --LAPTTP------EKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPT 590
Query: 1953 LEDLAGFKELFQTPGTDKPTTDEKTTKIACKSPQPDPVDTPAST---KQRPKRNLRKADV 2009
+ TP PTT ++T K P + PA T K PK
Sbjct: 591 TPK----EPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTK 646
Query: 2010 EEEFLALRKRTPSA--GKAMDTPK-PAVSDEKNINTFVETPVQKLDLLGNLPGSKRQPQ- 2065
E K P+ G A TPK PA + K TP G P + ++P
Sbjct: 647 EPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKE--PAPTTPK------GTAPTTLKEPAP 698
Query: 2066 -TPKEKAEALEDLVGFKELFQTPGHTEESMTDDKITEVSCKSPQPESFKTSRSSKQRLKI 2124
TPK+ A KEL T S T DK + K P + K + +
Sbjct: 699 TTPKKPAP--------KELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPA 750
Query: 2125 PLVKVDMKEEPLAVSKLTRTSGETTQTHTEPTGDSKSI------KAFKESPKQILDPAAS 2178
P VS T T E T H P + + KA + SPK+ P
Sbjct: 751 PTTPETPPPTTSEVSTPTTTK-EPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTK 809
Query: 2179 VTGSRRQLRTRKEKARALE-DLVDFKELFSA-PGHTEESMTI-DKNTKIPCKSPPPELTD 2235
+ + T K + E DL E +A P T+E+ T +K T+ + ++T
Sbjct: 810 TPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTS 869
Query: 2236 TAT------------STKRCPKTRPRKEVKEELSAVERLTQTSGQSTHTHKEPASGDEGI 2283
T T +T PK K+ + + +T+ A+ +
Sbjct: 870 TTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQ 929
Query: 2284 KVLKQRAKKKPNPVEEEPSRRRPRAPKEKAQPLEDLAGFTELSETSGHTQESLTAGKATK 2343
K K A KKP ++ + R R PK P + + EL+ TS + L + T
Sbjct: 930 KPTK--APKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAML---QTTT 984
Query: 2344 IPCESPPLEVVDTTASTK 2361
P ++P ++V+ ++
Sbjct: 985 RPNQTPNSKLVEVNPKSE 1002
Score = 87.4 bits (215), Expect = 2e-16
Identities = 220/890 (24%), Positives = 302/890 (33%), Gaps = 109/890 (12%)
Query: 675 KEELLAVGKFTRT-SGETTHTHREPAGDGKSIRTFKESPKQILDPAAR---VTGMKKWPR 730
KE L V K T + ETT T+++ + DGK T + + I +A+ T
Sbjct: 179 KETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKP 238
Query: 731 TPKEEAQSL-EDLAGFKELFQTPGPSEESMTDEKTTKIACKSPPPESVD-TPTSTKQWPK 788
TPK E + L KE T S T ++ T KS P + PT+TK P
Sbjct: 239 TPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPT 298
Query: 789 RSLRKADVEEEFLALRKLTPSAGKAMLTPKPAGGDEKDIKAFMGTPVQKLDLAGTLPGSK 848
A + A TP T +PA K P + A T P K
Sbjct: 299 TPKEPAPTTTKEPA--PTTPKEPAPTTTKEPAPTTTK------SAPTTPKEPAPTTP-KK 349
Query: 849 RQLQTPKEKAQALEDLAGFKELFQTPGHTEELVAAGKTTKIPCDSPQSDPVDTPTSTKQR 908
TPKE A KE TP +E TTK P + +P T
Sbjct: 350 PAPTTPKEPAPTTP-----KE--PTPTTPKE---PAPTTKEPAPTTPKEPAPT------A 393
Query: 909 PKRSIRKADVEGELLACRNLMPSAGKAMHTPKPSVGEEKDIIIFVGTPVQKLDLTENLTG 968
PK+ E + P+ K P P+ +E P + T
Sbjct: 394 PKKPAPTTPKEPAPTTPKEPAPTTTK---EPSPTTPKEPAPTTTKSAPTTTKEPAP--TT 448
Query: 969 SKRRPQTPKEEAQALEDLTGFKELFQTPGHTEEAVAAGKTTKMPCESSPPESADT----- 1023
+K P TPKE + T KE P T A T K P ++P E A T
Sbjct: 449 TKSAPTTPKEPSP-----TTTKE----PAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP 499
Query: 1024 -PTSTRR----QPKTPLEKRDVQKELSALKKLTQTSGE----TTHTDKVPGGEDKSINAF 1074
PT+T++ PK P + + KKLT T+ E TT P ++
Sbjct: 500 APTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTT 559
Query: 1075 RE----TAKQKLDPAASVTGSKRHPKTKEKAQPLEDLAGL-KELFQTPVCTDKPTTHEKT 1129
E T ++ P + PK P E KE T PTT + T
Sbjct: 560 PEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGT 619
Query: 1130 TKIACRSQPDPVDTPTSSKPQSKRSLRKVDVEEEFFALRKRTPSA--GKAMHTPK-PAVS 1186
+ +P P T KP K E K P+ G A TPK PA +
Sbjct: 620 APTTLK-EPAPT---TPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPT 675
Query: 1187 GEKNIYAFMGTPVQKLDLTENLTGSKRRLQTPKEKAQALEDLAGFKELFQTRGHTEESMT 1246
TP + T T T KE A KEL T S T
Sbjct: 676 ----------TPKEPAPTTPKGTAP----TTLKEPAPTTPKKPAPKELAPTTTKGPTSTT 721
Query: 1247 NDKTAKVACKSSQPDPDKNPASSKRRLKTSLGKVGVKEELLAVGKLTQTSGETTHTHTEP 1306
+DK A K + P K PA + + V T T+ E T H P
Sbjct: 722 SDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPT-TTKEPTTIHKSP 780
Query: 1307 TGDGKSM------KAFMESPKQI-LDSAASLTGSKRQLRTPKGKSEVPEDLAGFIE-LFQ 1358
+ KA SPK+ + + + +K ++ T DL E
Sbjct: 781 DESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTA 840
Query: 1359 TPSHTKE-SMTNEKTTKVSYRASQPDLVDTPTSSKPQPKRSLRKADTEEEFLAFRKQTPS 1417
P TKE + T EKTT+ A+ + T T K + K T + K+T +
Sbjct: 841 APKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTIT 900
Query: 1418 AGKAMHTPKPAVGEEKDINTFLGTPVQKLDQPGNLPGSNRRLQTRKEKAQALEELTGFRE 1477
+ M+ P+ + KD T K +P P + T+K K + R+
Sbjct: 901 TTEIMNKPE-ETAKPKDRATNSKATTPKPQKPTKAP--KKPTSTKKPKT-----MPRVRK 952
Query: 1478 LFQTPCTDNPTTDEKTTKKILCKSPQSDPADTPTNTKQRPKRSLKKADVE 1527
TP T K T + +P S A+ T RP ++ VE
Sbjct: 953 PKTTP------TPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVE 996
Score = 78.2 bits (191), Expect = 1e-13
Identities = 201/943 (21%), Positives = 296/943 (31%), Gaps = 142/943 (15%)
Query: 1705 TPK----EEAQSLEDLAGFKELFQTPD-----HTEESTTDDKTTKIACKSPPPESMDTPT 1755
TPK +EA S D FK TPD H + ST+ TT A P S+ +
Sbjct: 120 TPKPPVVDEAGSGLDNGDFK--VTTPDTSTTQHNKVSTSPKITT--AKPINPRPSLPPNS 175
Query: 1756 STRRRPKTPLGKRDIVEELSALKQLTQTTHTDKVPGDEDKGINVFRETAKQKLDPAASVT 1815
T + + K VE QT+ K K +T+ + L P + V
Sbjct: 176 DTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVL 235
Query: 1816 G--SKRQPRTPKGKAQPLEDLAGLKELFQTPICTDKPTTHEKTTKIACRSPQPDPVG--- 1870
+ + T KG A L KE PTT ++ + P P +
Sbjct: 236 AKPTPKAETTTKGPA-----LTTPKE--------PTPTTPKEPASTTPKEPTPTTIKSAP 282
Query: 1871 -TPTIFKPQSKRSLRKADVEEESLALRKRTPSVGKAMDTPKPAGGDEKDMKAFMGTPVQK 1929
TP P + +S E ++ P+ K P P E P
Sbjct: 283 TTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKE---PAPTTTKEPAPTTTKSAPTTP 339
Query: 1930 LDLPGNLPGSKRWPQTPKEKAQALEDLAGFKELFQTPGTDKPTTDEKTTKIACKSPQPDP 1989
+ P K P TPKE A TP PTT ++ K P P
Sbjct: 340 KE-PAPTTPKKPAPTTPKEPAPT------------TPKEPTPTTPKEPAPTT-KEPAPTT 385
Query: 1990 VDTPASTKQRPKRNLRKADVEEEFLALRKRTPSAGK--AMDTPK-PAVSDEKNINTFVET 2046
PA T PK+ E ++ P+ K + TPK PA + K+ T +
Sbjct: 386 PKEPAPTA--PKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKE 443
Query: 2047 PVQKLDLLGNLPGSKRQPQTPKEKAEALEDLVGFKELFQTPGHTEESMTDDKITEVSCKS 2106
P +K P TPKE + KE T T K + K
Sbjct: 444 PAPTT--------TKSAPTTPKEPSPTTT-----KEPAPTTPKEPAPTTPKKPAPTTPKE 490
Query: 2107 PQPESFKTSRSSKQRLKIPLVKVDMKEEPLAVSKLTRTSGETTQTHTEPTGDSKSIKAFK 2166
P P + K + + P +EP + + + TT PT K
Sbjct: 491 PAPTTPKEPAPTTTKKPAPTTP----KEPAPTTP--KETAPTTPKKLTPTTPEKLAPTTP 544
Query: 2167 ESPKQILDPAASVTGSRRQLRTRKEKARALEDLVDFKELFSAPGHTEESMTIDKNTKIPC 2226
E P + T T E+ P T K P
Sbjct: 545 EKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPA 604
Query: 2227 KSPPPELTDTA------TSTKRCPKTRPRKEVKEELSAVERLTQTSGQSTHTHKEPASGD 2280
+ P E T T+ K T P+K +EL+ T KEP S
Sbjct: 605 PTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPT------------TTKEPTS-- 650
Query: 2281 EGIKVLKQRAKKKPNPVEEEPSRRRPRAPKEKAQPLEDLAGFTELSETSGHTQESLTAGK 2340
KP P P P PKE A T T+ T +
Sbjct: 651 --------TTCDKPAPTT--PKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKE----P 696
Query: 2341 ATKIPCESPPLEVVDTTASTKRHLRTRVQKVQVKEEPSAVKFTQTSGETTDADKEPAGED 2400
A P + P E+ TT T+ ++P+ +T+ TT + P
Sbjct: 697 APTTPKKPAPKELAPTT--------TKGPTSTTSDKPAPTTPKETA-PTTPKEPAPTTPK 747
Query: 2401 KGIKALKESAKQTPAPAASVTGSRRRPRAPRESAQAIEDLAGFKDPAAGHTEESMTDDKT 2460
K E+ T + ++ T ++ + ++ +L+ P A T
Sbjct: 748 KPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPT 807
Query: 2461 TKIPCKSSPELEDTATSS------KRRPRTRAQKVEVKEELLAVGKLTQTSGETTHTDKE 2514
TK P + PE+ TA + P T ++ +E + T S T T +
Sbjct: 808 TKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQV 867
Query: 2515 PVGEGKGTKAFK-------QPAKRKLDAEDVIGSRRQPRAPKEKAQPLEDLASFQELSQT 2567
+ T FK A + + I + P+E A+P + + + +
Sbjct: 868 TSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPK 927
Query: 2568 PGHTEELANGAADSFTSAPKQTPDSGKPLKISRRVLRAPKVEP 2610
P T APK+ + KP + R +R PK P
Sbjct: 928 P-----------QKPTKAPKKPTSTKKPKTMPR--VRKPKTTP 957
Score = 66.2 bits (160), Expect = 4e-10
Identities = 189/834 (22%), Positives = 263/834 (31%), Gaps = 139/834 (16%)
Query: 878 EELVAAGKTTKIPCDSPQSDPVDTPTSTKQRPKRSIRKADVEGELLACRNLMPSA----- 932
E + K T + ++ ++ + TST + K + K E + ++L P++
Sbjct: 180 ETSLTVNKETTV--ETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAK 237
Query: 933 ----------GKAMHTPK-PSVGEEKDIIIFVGTPVQKLDLTENLTGSKRRPQTPKEEAQ 981
G A+ TPK P+ K+ P T K P TPKE A
Sbjct: 238 PTPKAETTTKGPALTTPKEPTPTTPKE-------PASTTPKEPTPTTIKSAPTTPKEPAP 290
Query: 982 ALEDLTGFKELFQTPGHTEEAVAAGKTTKMPCESSPPESADT------PTSTRRQPKTPL 1035
T K TP A TTK P ++P E A T PT+T+ P TP
Sbjct: 291 -----TTTKSAPTTPKEP-----APTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPK 340
Query: 1036 EKRDVQKELSALKKLTQTSGETTHTDKVPGGEDKSINAFRETAKQKLDPAASVTGSKRHP 1095
E + A + TT + P + +E A A K P
Sbjct: 341 EPAPTTPKKPA-PTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAP 399
Query: 1096 KTKEKAQPLEDLAGLKELFQTPVCTDKPTTHEK----TTKIACRSQPDPVDTPTSSKPQS 1151
T ++ P KE T PTT ++ TTK A + +P T T S P +
Sbjct: 400 TTPKEPAPTTP----KEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTT 455
Query: 1152 KRSLRKVDVEEEFFALRKRTPSAGKAMHTPKPAVSGEKNIYAFMGTPVQKLDLTENLTGS 1211
+ +E TP KPA + K TP + T
Sbjct: 456 PKEPSPTTTKEP----APTTPKEPAPTTPKKPAPTTPKE--PAPTTPKEPAPTTT----K 505
Query: 1212 KRRLQTPKEKAQALEDLAGFKELFQTRGHTEESMTNDKTAKVACKSSQPDPDKN--PASS 1269
K TPKE A KE T T +K A + P + P +
Sbjct: 506 KPAPTTPKEPAPTTP-----KETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTP 560
Query: 1270 KRRLKTSLGKVGVKEELLAVGKLTQTSGETTHTHTEPTGDGKSMKAFMESPKQILDSAAS 1329
+ T+ + A + TT PT + + +
Sbjct: 561 EEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTA 620
Query: 1330 LTGSKRQLRTPKGKSEVPEDLAGFIELFQTPSHTKE--SMTNEKTTKVSYRASQPDLVDT 1387
T K T K P++LA P+ TKE S T +K + + + P
Sbjct: 621 PTTLKEPAPTTP-KKPAPKELA--------PTTTKEPTSTTCDKPAPTTPKGTAP----- 666
Query: 1388 PTSSKPQPKRSLRKADTEEEFLAFRKQTPSAGKAMHTPKPAVGEEKDINTFLGTPVQKLD 1447
T +P P A T + A T A TPK +E T G D
Sbjct: 667 TTPKEPAPTTPKEPAPTTPKGTA---PTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSD 723
Query: 1448 QPGNLPGSNRRLQTRKEKAQALEELTGFRELFQTPCTDNPTTDEKTTKKILCKSPQSDPA 1507
+P T KE A TP PTT E P +
Sbjct: 724 KPAPTTPKETAPTTPKEPAPT------------TPKKPAPTTPE-------TPPPTTSEV 764
Query: 1508 DTPTNTKQRPKRSLKKADVEEEFLAFRKLTPSAGKAMHTPKAAVGEEKDINTFVGTPVEK 1567
TPT TK+ P K D + TP A TPKA K+ G P K
Sbjct: 765 STPTTTKE-PTTIHKSPD---------ESTPEL-SAEPTPKALENSPKE----PGVPTTK 809
Query: 1568 LDLLGNLPGSKRRPQTPKEKAKALEDLAGFKELFQTPGHT--------EESMTDDKITEV 1619
P + + T K K E ++L TP T E + T +K TE
Sbjct: 810 ------TPAATKPEMTTTAKDKTTE-----RDLRTTPETTTAAPKMTKETATTTEKTTES 858
Query: 1620 SCKSPQPDPVKTPTSSKQRLKISLGKVGVKEEVLPVGKLTQTSGKTTQTHRETA 1673
+ T T KI+ K + K T T+ + ETA
Sbjct: 859 KITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETA 912
Score = 55.8 bits (133), Expect = 6e-07
Identities = 212/970 (21%), Positives = 302/970 (31%), Gaps = 123/970 (12%)
Query: 1086 ASVTGSKRHPKTKEKAQP---LEDLAGL---KELFQTPVCTDKPTTHEKTTKIACRSQPD 1139
A V +K++ +TK+K P + D AG F+ T H K + +
Sbjct: 105 AEVKDNKKN-RTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAK 163
Query: 1140 PVDTPTSSKPQSKRSLR-KVDVEEEFFALRKRTPSAGKAMHTPKPAVSGEKNIYAFMGTP 1198
P++ S P S S + V +E K T + K T EK A
Sbjct: 164 PINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTD----GKEKTTSAKETQS 219
Query: 1199 VQKLDLTENLTGSKRRLQTPKEKAQALED---LAGFKELFQTRGHTEESMTNDKTAKVAC 1255
++K ++L + + L P KA+ L KE T S T +
Sbjct: 220 IEKTS-AKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTI 278
Query: 1256 KSSQPDPDKNPASSKRRLKTSLGKVGVKEELLAVGKLTQTSGETTHTHTEPTGDGKSMKA 1315
KS+ P K PA + + + K TT PT +
Sbjct: 279 KSAPTTP-KEPAPTTTKSAPTTPK---------------EPAPTTTKEPAPTTPKEPAPT 322
Query: 1316 FMESPKQILDSAASLTGSKRQLRTPKGKSEV-PEDLAGFIELFQTPSHTKESMTNEK--- 1371
+ P +A T + TPK + P++ A TP+ KE K
Sbjct: 323 TTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPA 382
Query: 1372 -TTKVSYRASQPDLVDTPTSSKPQPKRSLRKADTEEEFLAFRKQTPSAGKAMHTPKPAVG 1430
TT + P T +P P A T ++ +P+ K +PA
Sbjct: 383 PTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTT-----KEPSPTTPK-----EPAPT 432
Query: 1431 EEKDINTFLGTPVQKLDQPGNLPGSNRRLQTRKEKAQALEELTGFRELFQTPCTDNPTTD 1490
K T P + T KE A TP PTT
Sbjct: 433 TTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPT------------TPKEPAPTTP 480
Query: 1491 EK---TTKKILCKSPQSDPADTPTNTKQ----RPKRSLKKADVEEEFLAFRKLTPSAGKA 1543
+K TT K + +PA PT TK+ PK E +KLTP+ +
Sbjct: 481 KKPAPTTPKEPAPTTPKEPA--PTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEK 538
Query: 1544 MHTPKAAVGEEKDINTFVGTPVEKLDLLGNLPGSKRRPQTPKEKAKALEDLAGF---KEL 1600
+ A EK T TP E L + P TP+E A A KE
Sbjct: 539 L----APTTPEKPAPT---TPEE----LAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEP 587
Query: 1601 FQTPGHTEESMTDDKITEVSCKSPQPDPVK--TPTSSKQRLKISLGKVGVKEEVLPVGKL 1658
T T + + K P K PT+ K+ + K KE K
Sbjct: 588 APTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTK- 646
Query: 1659 TQTSGKTTQTHRETAGDGKSIKAFKESAKQMLDPANYGTGMERWPRTPKEEAQSLEDLAG 1718
+ + T T G + KE A T P T KE A +
Sbjct: 647 -EPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPA 705
Query: 1719 FKELFQTPDHTEESTTDDKTTKIACKSPPPESMDTPTST---RRRPKTPLGKRDIVEELS 1775
KEL T STT DK K P + P T + P TP E+S
Sbjct: 706 PKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVS 765
Query: 1776 ALKQLTQTTHTDKVPGDEDKGINVFRETAKQKLDPAASVTG---SKRQPRTPKGKAQPLE 1832
+ T K P + ++ E + L+ + G +K T +
Sbjct: 766 TPTTTKEPTTIHKSPDESTPELSA--EPTPKALENSPKEPGVPTTKTPAATKPEMTTTAK 823
Query: 1833 DLAGLKELFQTPICT--------DKPTTHEKTTKIACRSPQPDPVGTPTIFKPQSKRSLR 1884
D ++L TP T + TT EKTT+ + T T K +
Sbjct: 824 DKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTL 883
Query: 1885 KADVEEESLALRKRTPSVGKAMDTPKPAGGDEKDMKAFMGTPVQKLDLPGNLPGSKRWPQ 1944
K + K+T + + M+ P+ KD K P P K+
Sbjct: 884 KTTTLAPKVTTTKKTITTTEIMNKPEET-AKPKDRATNSKATTPKPQKPTKAP--KKPTS 940
Query: 1945 TPKEKAQALEDLAGFKELFQTPGTDKPTTDEKTTKIACKSPQPDPVDTPA----STKQRP 2000
T K K P KP T K+ P+ +P A T RP
Sbjct: 941 TKKPKTM--------------PRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRP 986
Query: 2001 KRNLRKADVE 2010
+ VE
Sbjct: 987 NQTPNSKLVE 996
Score = 54.3 bits (129), Expect = 2e-06
Identities = 148/598 (24%), Positives = 203/598 (33%), Gaps = 79/598 (13%)
Query: 634 APKSEKGKITKMPCQSLQPEPINTPTHTKQQLKASLGKVGVKEELLAVGKFTRTSGETTH 693
APK K P + EP PT TK+ + KE T S TT
Sbjct: 393 APKKPAPTTPKEPAPTTPKEP--APTTTKEPSPTT-----PKEP----APTTTKSAPTTT 441
Query: 694 THREPAGDGKSIRTFKE-SPKQILDPA-------ARVTGMKKWPRTPKEEAQSLEDLAGF 745
P + T KE SP +PA A T K P TPKE A +
Sbjct: 442 KEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTP----- 496
Query: 746 KELFQTPGPSEESMTDEKTTKIACKSPPPESVDTP-------TSTKQWPKRSLRKADVEE 798
+ P P+ T K + P E+ T T K P + A
Sbjct: 497 ----KEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTP 552
Query: 799 EFLAL---RKLTPSAGK--AMLTPKPAGGDEKDIKAFMGTPVQKLDLAGTLPGSKRQLQT 853
E LA + TP+ + A TPK A + A P + A T P T
Sbjct: 553 EELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPA----PTTPKEPAPTTPKEPAPT-T 607
Query: 854 PKEKAQALEDLAGFKELFQ----TPGHTEELVAAGKTTKIP----CDSPQ-SDPVDTPTS 904
PKE A L + TP A TTK P CD P + P T +
Sbjct: 608 PKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPT 667
Query: 905 TKQRPKRSIRKADVEGELLACRNLMPSAGK--AMHTPKPSVGEEKDIIIFVGTPVQKLDL 962
T + P + K E + P+ K A TPK +E G D
Sbjct: 668 TPKEPAPTTPK---EPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDK 724
Query: 963 TENLTGSKRRPQTPKEEAQALEDLTGFKELFQTPGHTEEAVAAGKTTKMPC-------ES 1015
T + P TPKE A +TP T V+ TTK P ES
Sbjct: 725 PAPTTPKETAPTTPKEPAPTTPKKPA-PTTPETPPPTTSEVSTPTTTKEPTTIHKSPDES 783
Query: 1016 SPPESAD-TPTSTRRQPKTPLEKRDVQKELSALKKLTQTSGETTHTDKVPGGEDKSINAF 1074
+P SA+ TP + PK P K +A K T+ + T++ ++ A
Sbjct: 784 TPELSAEPTPKALENSPKEP--GVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAA 841
Query: 1075 RETAKQKLDPAASVTGSK-RHPKTKEKAQPLEDLAGLK-ELFQTPVCTDKPTTHEKT-TK 1131
+ K+ T SK T+ + +D K +T K TT +KT T
Sbjct: 842 PKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITT 901
Query: 1132 IACRSQPD----PVDTPTSSKPQSKRSLRKVDVEEEFFALR--KRTPSAGKAMHTPKP 1183
++P+ P D T+SK + + + ++ + + K P K TP P
Sbjct: 902 TEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTP 959
Score = 38.9 bits (89), Expect = 0.075
Identities = 102/461 (22%), Positives = 150/461 (32%), Gaps = 88/461 (19%)
Query: 634 APKSEKGKITKMPCQSLQPEPI-NTPTHTKQQLKASLGKVGVKEELLAVGKFTRTSGETT 692
APK TK P + +P TP T KE K G
Sbjct: 636 APKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPK-----GTAP 690
Query: 693 HTHREPAGDGKSIRTFKESPKQILDPAAR----VTGMKKWPRTPKEEAQSLEDLAGFKEL 748
T +EPA K +PK++ + T K P TPKE A +
Sbjct: 691 TTLKEPAPTTPK----KPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTP-------- 738
Query: 749 FQTPGPSEESMTDEKTTKIACKSPPPES--VDTPTSTKQWPKRSLRKADVEEEFLALRKL 806
+ P P+ T +K ++PPP + V TPT+TK+ ++ K+ E
Sbjct: 739 -KEPAPT----TPKKPAPTTPETPPPTTSEVSTPTTTKE--PTTIHKSPDES-------- 783
Query: 807 TPSAGKAMLTPKPAGGDEKDIKAFMGTPVQKLDLAGTLPGSKRQLQTPKEKAQALEDLAG 866
TP A TPK K+ G P K A T E +D
Sbjct: 784 TPELS-AEPTPKALENSPKE----PGVPTTKTPAA-----------TKPEMTTTAKDKTT 827
Query: 867 FKELFQTPGHTEELVAAGKTTKIPCDSPQSDPVDTPTSTKQRPKRSIRKADVEGELLACR 926
++L TP E AA K TK +T T+T++ + I + +
Sbjct: 828 ERDLRTTP---ETTTAAPKMTK-----------ETATTTEKTTESKITATTTQVTSTTTQ 873
Query: 927 NLMPSAGKAMHTPKPSVGEEKDIIIFVGTPVQKLDLTENLTGSKRRPQTPKEEAQALEDL 986
+ P + T T K+ T+ + P+E A+ +
Sbjct: 874 DTTPFKITTLKTT---------------TLAPKVTTTKKTITTTEIMNKPEETAKPKDRA 918
Query: 987 TGFKELFQTPGHTEEAVAAGKTTKMPCESSPPESADTPTSTRRQPKTPLEKRDVQKELSA 1046
T K P +A +TK P T + R+ T E + A
Sbjct: 919 TNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEA 978
Query: 1047 LKKLTQTSGETTHTDKV---PGGEDKSINAFRETAKQKLDP 1084
+ + T +T ++ V P ED A ET L P
Sbjct: 979 MLQTTTRPNQTPNSKLVEVNPKSEDAG-GAEGETPHMLLRP 1018
>gi|238624188 diffuse panbronchiolitis critical region 1 protein [Homo
sapiens]
Length = 1393
Score = 85.5 bits (210), Expect = 7e-16
Identities = 168/779 (21%), Positives = 292/779 (37%), Gaps = 105/779 (13%)
Query: 2133 EEPLAVSKLTRTSGETTQTHTEPTGDSKSIKAFKESPKQILDPAASVTGSRRQLRTRKEK 2192
++P+ ++ + ++T TH E G K +PK ++ S TG R +
Sbjct: 130 KDPMIRNQRSVDPADSTTTHKESAGK----KHITPAPKSKINCRKSTTGKSTVTRKSDKT 185
Query: 2193 ARALEDLVDFKELFSAPGH---TEESMTIDKNTKIPCKSPPPELTDTATSTKRCPKTRPR 2249
R LE + + S H T + + TK S P ++T + +T + T
Sbjct: 186 GRPLEKSMSTLDKTSTSSHKTTTSFHNSGNSQTKQKSTSFPEKITAASKTTYKTTGTPEE 245
Query: 2250 KEVKEELSAVERLTQTSGQSTHTHKEPASGDEGIKVLKQ-------RAKKKPNPVEEEPS 2302
E E+ + ++T +E S +E + L + A + P EP+
Sbjct: 246 SEKTEDSRTTVASDKLLTKTTKNIQETISANELTQSLAEPTEHGGRTANENNTPSPAEPT 305
Query: 2303 RRRPRAPKEK-----AQPLED---LAGFTELSETSGHTQE-SLTAGKATKI-PCESPPLE 2352
R R E A+P+E+ A +G T+ +TA + T + P E P E
Sbjct: 306 ENRERTANENTTLSPAEPIENRERTANENTAPFPAGPTENREMTANENTTLFPAE--PTE 363
Query: 2353 VVDTTASTKRHLRTRVQKVQVKEEPSAVKFTQTSGETTD-ADKEPAGEDKGIKALKESAK 2411
+ TA+ + + + + E + T + E T+ ++ P DK + ES +
Sbjct: 364 HGERTAN-ENTTPSPAEPTEHGERTANENTTPSPAEPTEHGERTPFANDKTTSSSAESTE 422
Query: 2412 ---QTPAPAASVTGSRRRPRAPRESAQAIEDLAGFKDPAAGHTE--ESMTDDKTTKIPCK 2466
+TP + T S P P E+ + + PA G TE E+ ++KTT P +
Sbjct: 423 HGERTPLANENTTPS---PAEPTENRERTANENTTPSPA-GPTENRETTANEKTTLSPVE 478
Query: 2467 SSPELEDTA----TSSKRRPRTRAQKVEVKEELLAVGKLTQTSGE-TTHTDKEPVGEGKG 2521
+ E TA T S P Q+ E K T +S E T H ++ P+
Sbjct: 479 PTENRETTANEKTTPSPAEPTENGQRTPFANE-----KTTSSSAEPTEHGERTPLANENT 533
Query: 2522 TKAFKQPAKRKLDAEDVIGSRRQPRAPKEKAQPLE--DLASFQELSQTPGHTEELANGAA 2579
T + +P + + E + P A+P E D TP E NG
Sbjct: 534 TPSPAEPTENR---ERTANEKTTP----SPAEPTENGDRTPLANEKTTPSLAEPTENGQR 586
Query: 2580 DSFTSAPKQTPDSGKPLKISRRVLRAPKVEPVGDVVSTRDPVKSQSK-SNTSLPPLPFKR 2638
F + K T S +P + R A + S +P +++ + +N + P P
Sbjct: 587 TPFAN-EKTTSSSAEPTEHEERTPLANE----NTTPSPAEPTENRERTANENTTPSP--A 639
Query: 2639 GGGKDGSVTGTKRLRCMPAPEEIVEELPASKKQRVAP---------------RARGKSSE 2683
G ++ +T ++ PA E A++K +P + S+E
Sbjct: 640 GPTENREMTANEKTTLFPAEPTENRERTANEKTTSSPAEPTENGQRTPFANEKTTSSSAE 699
Query: 2684 PVVIMKRS-LRTSAKRIEPAEELNSNDMKTNKEEHKLQDSVPENKGISLRSRRQNKTEAE 2742
P +R+ L + PAE + + N++ EN+ R+ +N T +
Sbjct: 700 PTEHGERTPLANENTTLSPAEPTENRERTANEKTTPFPAEPTENRE---RTANENTTPSP 756
Query: 2743 QQITEVFVLAERIEINRNEKKPM---KTSPEMDIQNPDDGARKPIPRDKVTEN-----KR 2794
Q TE ++ P+ KT+P + + ++G R P +K T + +
Sbjct: 757 AQPTE-----------NGDRTPLANEKTTPSL-AEPTENGKRTPFANEKTTSSSAEPTEH 804
Query: 2795 CLRSARQNESSQPKVAEESGGQKSAKVLMQNQKGKGEAGNSDSMCLRSRKTKSQPAAST 2853
R+ NE++ AE + ++ Q N +S + KT PA T
Sbjct: 805 AERTPLANENTTSSPAEPTENRERTANEKTTQFPAEPTENRESTA--NEKTTPFPAEPT 861
Score = 75.1 bits (183), Expect = 9e-13
Identities = 250/1296 (19%), Positives = 445/1296 (34%), Gaps = 145/1296 (11%)
Query: 1081 KLDPAASVTGSKRHPKTKEKAQPLEDLAGLKELFQTPVCTDKPTTHEKTTKIACRSQPDP 1140
+L + + KRH T ++P TDKPT + KT I +S D
Sbjct: 73 ELPKSTEIHEQKRHCNTTRHSKP----------------TDKPTGNSKT--IDHKSSTDN 114
Query: 1141 VDTPTSSKPQSKRSLRKVDVEEEFFALRKRTPSAGKAMHTPKPAVSGEKNIYAFMGTPVQ 1200
+ P +S+ S + + + R P+ H +G+K+I P
Sbjct: 115 HEAPPTSEENSSNQGKDPMIRNQ----RSVDPADSTTTHKES---AGKKHITP---APKS 164
Query: 1201 KLDLTENLTGSKRRLQTPKEKAQALEDLAGFKELFQTRGH-TEESMTNDKTAKVACKSSQ 1259
K++ ++ TG + + + LE + T H T S N ++ KS+
Sbjct: 165 KINCRKSTTGKSTVTRKSDKTGRPLEKSMSTLDKTSTSSHKTTTSFHNSGNSQTKQKSTS 224
Query: 1260 PDPDKNPASSKRRLKTSLGKVGVKEELLAVGKLTQTSGETTHTHTEPTGDGKSMKAFMES 1319
P+K A+SK KT+ G EE S +T + T D K ++
Sbjct: 225 -FPEKITAASKTTYKTT----GTPEE----------SEKTEDSRTTVASD----KLLTKT 265
Query: 1320 PKQILD--SAASLTGSKRQLRTPKGKSEVPEDLAGFIELFQTPSHTKESMTNEKTT---- 1373
K I + SA LT S + G++ + E P+ +E NE TT
Sbjct: 266 TKNIQETISANELTQSLAEPTEHGGRTANENNTPSPAE----PTENRERTANENTTLSPA 321
Query: 1374 -KVSYRASQPDLVDTPTSSKPQPKRSLRKADTEEEFLAF-RKQTPSAGKAMHTPKPAV-- 1429
+ R + P + P R + + F A + TP PA
Sbjct: 322 EPIENRERTANENTAPFPAGPTENREMTANENTTLFPAEPTEHGERTANENTTPSPAEPT 381
Query: 1430 --GEEKDINTFLGTPVQKLDQPGNLPGSNRRLQTRKEKAQALEELTGFRELFQTPCTDNP 1487
GE +P + + P +N + + ++ E T TP P
Sbjct: 382 EHGERTANENTTPSPAEPTEHGERTPFANDKTTSSSAESTEHGERTPLANENTTPSPAEP 441
Query: 1488 TTD-EKTTKKILCKSPQSDPADTPTNTKQRPKRSLKKADVEEEFLAFRKLTPSAGKAMHT 1546
T + E+T + SP + T ++ S + E A K TPS +
Sbjct: 442 TENRERTANENTTPSPAGPTENRETTANEKTTLSPVEPTENRETTANEKTTPSPAEPTEN 501
Query: 1547 PKAAVGEEKDINTFVGTPVEKLDLLGNLP-GSKRRPQTPKEKAKALEDLAGFKELFQTPG 1605
+ + + P E + P ++ +P E + E A K TP
Sbjct: 502 GQRTPFANEKTTSSSAEPTEHGE---RTPLANENTTPSPAEPTENRERTANEK---TTPS 555
Query: 1606 HTEESMTDDKI------TEVSCKSPQPDPVKTPTSSKQRLKISLGKVGVKEEV-LPVGKL 1658
E + D+ T S P + +TP ++++ S +E L
Sbjct: 556 PAEPTENGDRTPLANEKTTPSLAEPTENGQRTPFANEKTTSSSAEPTEHEERTPLANENT 615
Query: 1659 TQTSGKTTQTHRETAGDGKSIKAFKESAKQMLDPANYGTGMERWPRTPKEEAQSLEDLAG 1718
T + + T+ TA + + + + + T E+ P E ++ E A
Sbjct: 616 TPSPAEPTENRERTANENTTPSPAGPTENREM------TANEKTTLFPAEPTENRERTAN 669
Query: 1719 FKELFQTPDHTEESTTDDKTTKIACKSPPPESMDTPTSTRRRPKTPLGKRDIVEELSALK 1778
K T E T + + T A + S + T +TPL + +
Sbjct: 670 EK----TTSSPAEPTENGQRTPFANEKTTSSSAE---PTEHGERTPLANENTTLSPAEPT 722
Query: 1779 QLTQTTHTDKVPGDEDKGINVFRETAKQKLDPAASVTGSKRQPRTPKGKAQPLEDLAGLK 1838
+ + T +K + TA + P+ + ++ RTP + LA
Sbjct: 723 ENRERTANEKTTPFPAEPTENRERTANENTTPSPA-QPTENGDRTPLANEKTTPSLAEPT 781
Query: 1839 EL-FQTPICTDKPTTHE-KTTKIACRSPQPDPVGTPTIFKPQSKRSLRKADVEEESLALR 1896
E +TP +K T+ + T+ A R+P + T + +P R E A
Sbjct: 782 ENGKRTPFANEKTTSSSAEPTEHAERTPLANENTTSSPAEPTENR---------ERTANE 832
Query: 1897 KRTPSVGKAMDTPKPAGGDEKDMKAFMGTPVQKLDLPGNLPGSKRWPQTPKEKAQALEDL 1956
K T + + + ++ F P + + N + P P E + + L
Sbjct: 833 KTTQFPAEPTENRESTANEK--TTPFPAEPTENREWTAN-ENTTLSPAEPTEH-EEMTPL 888
Query: 1957 AGFKELFQTP-----GTDKPTTDEKTTKIACKSPQPDPVDTPASTKQRPKRNLRKADVEE 2011
A K G P T+EKTT + + + A+ P R +
Sbjct: 889 ANEKTTLSPAEPTENGERTPFTNEKTTPSSAEPTEHGERTPLANEITTPSR--AEPTEHG 946
Query: 2012 EFLALRKRTPSAGKAMDTPKPAVSDEKNINTFVETPVQKLDLLGNLPGSKRQPQTPKEKA 2071
E +A K TPS K + + V+++ ++ T + L N + P E
Sbjct: 947 ERIANEKATPSPAKPTEHGETTVNEDTTPSSAEPTENGERTPLAN-ENTTTSPTESTEHG 1005
Query: 2072 EALEDLVGFKELFQTPGHTEESMTDDKITEVSCKSPQPESFKTSRSSKQRLKIPLVKVDM 2131
E + + H E + + ++ T S P T +++ P+ +
Sbjct: 1006 ERTANEKTTPSPAEPTEHGERTPSANEKTIPSPAKPTEHEEMTPSANENTTPSPVKPTEH 1065
Query: 2132 KEE-PLAVSKLTRTSGETTQTHTEPTGDSKSIKAFKESP----KQILDPAASVTGSRRQL 2186
E+ LA K+T + T+ + T ++ I P ++ P +T S +
Sbjct: 1066 GEKTTLANEKITLSPEGPTEHGAKTTSANEKITPSLAKPTEHGERTTSPNDKITSSAAES 1125
Query: 2187 RTRKEKARALEDLVDFKELFSAPGH-----TEESMTIDKNTKIPCKSP--PPELTDTATS 2239
+++A + + AP ++ +K T++ KS P + T T
Sbjct: 1126 TEHRDRATSANVIT------PAPAEPIKHAKRTTLAHEKMTQVTEKSTEHPEKTTSTTEK 1179
Query: 2240 TKRCPKTRPRKEVKEELSAVERLTQTSGQSTHTHKEPASGDEGIKVLKQRAKKKPNPVEE 2299
T R P+ K L + E+ T G++T ++P + + K PV+
Sbjct: 1180 TTRTPE-------KPTLYS-EKTICTKGKNTPVPEKPTENLGNTTLTTETIKA---PVKS 1228
Query: 2300 EPSRRRPRAPKEKAQPLEDLAGFTELSETSGHTQES 2335
+ + A + +P + G L+ TS H ++
Sbjct: 1229 TENPEKTAAVTKTIKPSVKVTGDKSLTTTSSHLNKT 1264
Score = 68.9 bits (167), Expect = 7e-11
Identities = 200/927 (21%), Positives = 304/927 (32%), Gaps = 136/927 (14%)
Query: 964 ENLTGSKRRPQTPKEEAQALEDLTGFKELFQTPGHTEEAVAAGKTTKMPCESSPPESADT 1023
EN T S P E D T T +A TT P E +
Sbjct: 390 ENTTPSPAEPTEHGERTPFANDKTTSSSAESTEHGERTPLANENTTPSPAEPTENRERTA 449
Query: 1024 PTSTRRQPKTPLEKRDVQKELSALKKLTQTSGETTHTDKVPGGEDKSINAFRETAKQKLD 1083
+T P P E R E +A +K T + E T + E + + T +
Sbjct: 450 NENTTPSPAGPTENR----ETTANEKTTLSPVEPTENRETTANEKTTPSPAEPTENGQRT 505
Query: 1084 PAAS--VTGSKRHP-------------KTKEKAQPLEDLAGLKELFQTPVCTD------- 1121
P A+ T S P T A+P E+ TP +
Sbjct: 506 PFANEKTTSSSAEPTEHGERTPLANENTTPSPAEPTENRERTANEKTTPSPAEPTENGDR 565
Query: 1122 KPTTHEKTTKIACRSQPDPVDTPTSSKPQSKRSLRKVDVEEEFFALRKRTPSAGKAMHTP 1181
P +EKTT + TP +++ + S + EE RTP A + TP
Sbjct: 566 TPLANEKTTPSLAEPTENGQRTPFANEKTTSSSAEPTEHEE-------RTPLANENT-TP 617
Query: 1182 KPAVSGE-KNIYAFMGTPVQKLDLTEN--LTGSKRRLQTPKEKAQALEDLAGFKELFQTR 1238
PA E + A T TEN +T +++ P E + E A K
Sbjct: 618 SPAEPTENRERTANENTTPSPAGPTENREMTANEKTTLFPAEPTENRERTANEKTTSSPA 677
Query: 1239 GHTEES----MTNDKTAKVACKSSQPDPDKNPASSKRRLKTSLGKVGVKE--ELLAVGKL 1292
TE N+KT + + ++ ++ P +++ T+L E E A K
Sbjct: 678 EPTENGQRTPFANEKTTSSSAEPTE-HGERTPLANE---NTTLSPAEPTENRERTANEKT 733
Query: 1293 TQTSGETTHTHTEPTGDGKSMKAFMESPKQILDSAASLTGSKRQLRTPKGKSEVPEDLAG 1352
T E T + + SP Q ++ RTP + LA
Sbjct: 734 TPFPAEPTENRERTANENTT-----PSPAQPTENGD---------RTPLANEKTTPSLAE 779
Query: 1353 FIELFQTPSHTKESMTNEKTTKVS----YRASQPDLVDTPTSSKPQPKRSLRKADTEEEF 1408
T + + NEKTT S A + L + T+S P R+ E+
Sbjct: 780 -----PTENGKRTPFANEKTTSSSAEPTEHAERTPLANENTTSSPAEPTENRERTANEKT 834
Query: 1409 LAF----RKQTPSAGKAMHTPKPAVGEEK-----DINTFLGTPVQKLDQPGNLPGSNRRL 1459
F + S TP PA E + NT L +P + + P +N +
Sbjct: 835 TQFPAEPTENRESTANEKTTPFPAEPTENREWTANENTTL-SPAEPTEHEEMTPLANEKT 893
Query: 1460 QTRKEKAQALEELTGFRELFQTPCTDNPTTDEKTTKKILCKSPQSDPADTPTNTKQRPKR 1519
+ E T F TP + PT + T P ++ TP+ +
Sbjct: 894 TLSPAEPTENGERTPFTNEKTTPSSAEPTEHGERT-------PLANEITTPSRAEPTE-- 944
Query: 1520 SLKKADVEEEFLAFRKLTPSAGKAMHTPKAAVGEEKDINTFVGTPVEKLDLLGNLPGSKR 1579
E +A K TPS K + V E+ ++ T + L N +
Sbjct: 945 -------HGERIANEKATPSPAKPTEHGETTVNEDTTPSSAEPTENGERTPLAN----EN 993
Query: 1580 RPQTPKEKAKALEDLAGFKEL----------FQTPGHTEESMTD-------DKITEVSCK 1622
+P E + E A K +TP E+++ +++T + +
Sbjct: 994 TTTSPTESTEHGERTANEKTTPSPAEPTEHGERTPSANEKTIPSPAKPTEHEEMTPSANE 1053
Query: 1623 SPQPDPVKTPTSSKQRL-----KISLGKVGVKEEVLPV----GKLTQTSGKTTQTHRETA 1673
+ P PVK PT ++ KI+L G E K+T + K T+ T
Sbjct: 1054 NTTPSPVK-PTEHGEKTTLANEKITLSPEGPTEHGAKTTSANEKITPSLAKPTEHGERTT 1112
Query: 1674 GDGKSIKAFKESAKQMLDPANYGTGMERWPRTPKEEAQSLEDLAGFKELFQTPDHTEEST 1733
I + + + D A + P P + A+ LA K T TE
Sbjct: 1113 SPNDKITSSAAESTEHRDRATSANVITPAPAEPIKHAKR-TTLAHEKMTQVTEKSTEHPE 1171
Query: 1734 TDDKTTKIACKSPPPESMDTPTSTRRRPKTPLGKRDIVEE--LSALKQLTQTTHTDKVPG 1791
TT+ ++P + PT + GK V E L T TT T K P
Sbjct: 1172 KTTSTTEKTTRTP-----EKPTLYSEKTICTKGKNTPVPEKPTENLGNTTLTTETIKAPV 1226
Query: 1792 DEDKGINVFRETAKQKLDPAASVTGSK 1818
+ K + P+ VTG K
Sbjct: 1227 KSTENPEKTAAVTK-TIKPSVKVTGDK 1252
Score = 60.1 bits (144), Expect = 3e-08
Identities = 189/953 (19%), Positives = 308/953 (32%), Gaps = 183/953 (19%)
Query: 1726 PDHTEESTTDDKTTKIACKSPPPESMDTPTSTRRRPK----TPLGKRD-IVEELSALKQL 1780
P E+T ++KTT + P E+ +T + + P T G+R E +
Sbjct: 460 PTENRETTANEKTTLSPVE--PTENRETTANEKTTPSPAEPTENGQRTPFANEKTTSSSA 517
Query: 1781 TQTTHTDKVP-GDEDKGINVFRETAKQKLDPAASVTGSKRQP-----RTPKGKAQPLEDL 1834
T H ++ P +E+ + T ++ T S +P RTP + L
Sbjct: 518 EPTEHGERTPLANENTTPSPAEPTENRERTANEKTTPSPAEPTENGDRTPLANEKTTPSL 577
Query: 1835 AGLKELFQ-TPICTDK-------PTTHEKTTKIACRSPQPDPVG-------------TPT 1873
A E Q TP +K PT HE+ T +A + P P TP+
Sbjct: 578 AEPTENGQRTPFANEKTTSSSAEPTEHEERTPLANENTTPSPAEPTENRERTANENTTPS 637
Query: 1874 IFKPQSKRSLRKADV----------EEESLALRKRTPSVGKAMD----TP---------- 1909
P R + + E A K T S + + TP
Sbjct: 638 PAGPTENREMTANEKTTLFPAEPTENRERTANEKTTSSPAEPTENGQRTPFANEKTTSSS 697
Query: 1910 -KPAGGDEKDMKAFMGTPVQKLDLPGNLPGSKRWPQTPKEKAQALEDLAGFKELFQTPGT 1968
+P E+ A T + + N + TP A+ E+ TP
Sbjct: 698 AEPTEHGERTPLANENTTLSPAEPTENRERTANEKTTPFP-AEPTENRERTANENTTPSP 756
Query: 1969 DKPTTDEKTTKIACKSPQPDPVDTPASTKQRPKRNLRKADVEEEFLALRKRTPSAGKAMD 2028
+PT + T +A + P + + K+ P N + E +RTP A +
Sbjct: 757 AQPTENGDRTPLANEKTTPSLAEPTENGKRTPFANEKTTSSSAEPTEHAERTPLANE-NT 815
Query: 2029 TPKPAVSDEKNINTFVETPVQKLDLLGNLPGSKRQPQTPKEKAEALEDLVGFKEL-FQTP 2087
T PA E T +++ Q P E E E K F
Sbjct: 816 TSSPAEPTENRERT----------------ANEKTTQFPAEPTENRESTANEKTTPFPAE 859
Query: 2088 GHTEESMTDDKITEVSCKSPQPESFKTSRSSKQRLKIPLVKVDMKEE-PLAVSKLTRTSG 2146
T ++ T +S P T ++++ P + E P K T +S
Sbjct: 860 PTENREWTANENTTLSPAEPTEHEEMTPLANEKTTLSPAEPTENGERTPFTNEKTTPSSA 919
Query: 2147 ETTQTHTEPTGDSKSIKAFKESPKQILDPAASVTGSRRQLRTRKEKARALEDLVDFKELF 2206
E T+ H E T + I T SR +
Sbjct: 920 EPTE-HGERTPLANEI----------------TTPSRAE--------------------- 941
Query: 2207 SAPGHTEESMTIDKNTKIPCKSPPPELTDTATSTKRCPKTRPRKEVKEELSAVERLTQTS 2266
P E + +K T P K P E +T + P + E E T TS
Sbjct: 942 --PTEHGERIANEKATPSPAK--PTEHGETTVNEDTTPSSAEPTENGERTPLANENTTTS 997
Query: 2267 GQSTHTHKEPASGDEGIKVLKQRAKKKPNPVEEEPSRRRPRAPKEKAQPLEDLAGFTELS 2326
+ H E + A +K P EP+ R P + + A TE
Sbjct: 998 PTESTEHGE------------RTANEKTTPSPAEPTEHGERTPSANEKTIPSPAKPTEHE 1045
Query: 2327 ETSGHTQESLTAGKATKIPCESPPLEVVDTTASTKRHLRTRVQKVQVKEEPSAVKFTQTS 2386
E + E+ T P P E + T +K+ + E T+
Sbjct: 1046 EMTPSANENTT-------PSPVKPTEHGEKTTLAN-------EKITLSPEGP----TEHG 1087
Query: 2387 GETTDADKEPAGEDKGIKALKESAKQTPAPAASVTGSRRRPRAPRESAQAIEDLAGFKDP 2446
+TT A+++ + E ++T +P +T S R+ A + +
Sbjct: 1088 AKTTSANEKIT---PSLAKPTEHGERTTSPNDKITSSAAESTEHRDRATSANVITPAPAE 1144
Query: 2447 AAGHTEE-SMTDDKTTKIPCKSSPELEDTATSSKRRPRTRAQKVEVKEELLAVGKLTQTS 2505
H + ++ +K T++ KS+ E T +++++ RT + E+ + T
Sbjct: 1145 PIKHAKRTTLAHEKMTQVTEKSTEHPEKTTSTTEKTTRTPEKPTLYSEKTIC------TK 1198
Query: 2506 GETTHTDKEPVGEGKG-----TKAFKQPAKRKLDAEDVIGSRRQPRAPKEKAQPLEDLAS 2560
G+ T ++P E G T+ K P K + E + A + +P +
Sbjct: 1199 GKNTPVPEKPT-ENLGNTTLTTETIKAPVKSTENPE-------KTAAVTKTIKPSVKVTG 1250
Query: 2561 FQELSQTPGHTEELANGAADSFTSAPKQTPDSGKPLKISRRVLRAPKVEPVGD 2613
+ L+ T H + T Q P L SR L + E G+
Sbjct: 1251 DKSLTTTSSHLNK---------TEVTHQVPTGSFTLITSRTKLSSITSEATGN 1294
Score = 58.2 bits (139), Expect = 1e-07
Identities = 205/1072 (19%), Positives = 345/1072 (32%), Gaps = 146/1072 (13%)
Query: 751 TPGPSEESMTDEKTTKIACKSPPPESVDTPTSTKQWPKRSLRKADVEEEFLALRKLTPSA 810
TP P+E + E+T P E ++ T E R++T +
Sbjct: 298 TPSPAEPTENRERTANENTTLSPAEPIENRERTANENTAPFPAGPTEN-----REMTANE 352
Query: 811 GKAMLTPKPAGGDEKDIKAFMGTPVQKLDLAGTLPGSKRQLQTPKEKAQALEDLAGFKEL 870
+ +P E+ + G ++ +P E + E +
Sbjct: 353 NTTLFPAEPTEHGERTANENTTPSPAEPTEHGERTANENTTPSPAEPTEHGERTPFAND- 411
Query: 871 FQTPGHTEELVAAGKTTKIPCDSPQSDPVDTPTSTKQRPKRSIRKADVEGELLACRNLMP 930
+T + E G+ T + ++ P + PT ++R A N P
Sbjct: 412 -KTTSSSAESTEHGERTPLANENTTPSPAE-PTENRERT--------------ANENTTP 455
Query: 931 SAGKAMHTPKPSVGEEKDIIIFVGTPVQKLDLTENLTGSKRRPQTPKEEAQALEDLTGFK 990
S + + E+ + T ++ E T S P + + T
Sbjct: 456 SPAGPTENRETTANEKTTLSPVEPTENRETTANEKTTPSPAEPTENGQRTPFANEKTTSS 515
Query: 991 ELFQTPGHTEEAVAAGKTTKMPCESSPPESADTPTSTRRQPKTPLEKRDVQKELSALKKL 1050
T +A TT P E + T P P E D + L+ K
Sbjct: 516 SAEPTEHGERTPLANENTTPSPAEPTENRERTANEKTTPSPAEPTENGD-RTPLANEKTT 574
Query: 1051 TQTSGETTHTDKVPGGEDKSINAFRE-TAKQKLDPAASVTGSKRHPKTKEKAQPLEDLAG 1109
+ T + + P +K+ ++ E T ++ P A+ T A+P E+
Sbjct: 575 PSLAEPTENGQRTPFANEKTTSSSAEPTEHEERTPLAN------ENTTPSPAEPTENRER 628
Query: 1110 LKELFQT-----PVCTDKPTTHEKTTKIACRSQPDPVDTPTSSKPQSKRSLRKVDVEEEF 1164
T P + T +EKTT + T + K S + + +
Sbjct: 629 TANENTTPSPAGPTENREMTANEKTTLFPAEPTENRERT-ANEKTTSSPAEPTENGQRTP 687
Query: 1165 FALRKRTPSAGKAMHTPKPAVSGEKNIYAFMGTPVQKLDLTENLTGSKRRLQTPKEKAQA 1224
FA K T S+ +P GE+ A T + + TEN R +T EK
Sbjct: 688 FANEKTTSSSA------EPTEHGERTPLANENTTLSPAEPTEN------RERTANEKT-- 733
Query: 1225 LEDLAGFKELFQTRGHTEESMTNDKTAKVACKSSQPDPDKNPASSKRRLKTSLGKVGVKE 1284
T E + ++TA S P +N
Sbjct: 734 ------------TPFPAEPTENRERTANENTTPSPAQPTEN------------------- 762
Query: 1285 ELLAVGKLTQTSGE-TTHTHTEPTGDGKSMKAFMESPKQILDSAASLTGSKRQLRTPKGK 1343
G T + E TT + EPT +GK E +++S ++ RTP
Sbjct: 763 -----GDRTPLANEKTTPSLAEPTENGKRTPFANEK-----TTSSSAEPTEHAERTPLAN 812
Query: 1344 SEVPEDLAGFIELFQTPSHTKESMTNEKTTK-----VSYRASQPDLVDTPTSSKPQPKRS 1398
A P+ +E NEKTT+ R S + TP ++P R
Sbjct: 813 ENTTSSPA-------EPTENRERTANEKTTQFPAEPTENRESTANEKTTPFPAEPTENRE 865
Query: 1399 LRKADTEEEFLAFRKQTPSAGKAMHTPKPAVGEEKDINTFLGTPVQKLDQPGNLPGSNRR 1458
T E P+ + M P E+ + +P + + P +N +
Sbjct: 866 W----TANENTTLSPAEPTEHEEM---TPLANEKTTL-----SPAEPTENGERTPFTNEK 913
Query: 1459 LQTRKEKAQALEELTGFRELFQTPCTDNPTT-DEKTTKKILCKSP--QSDPADTPTNTKQ 1515
+ E T TP PT E+ + SP ++ +T N
Sbjct: 914 TTPSSAEPTEHGERTPLANEITTPSRAEPTEHGERIANEKATPSPAKPTEHGETTVNEDT 973
Query: 1516 RPKRSLKKADVEEEFLAFRKLTPSAGKAMHTPKAAVGEEKDINTFVGTPVEKLDLLGNLP 1575
P + + E LA T S T GE +P E + P
Sbjct: 974 TPSSAEPTENGERTPLANENTTTSP-----TESTEHGERTANEKTTPSPAEPTEHGERTP 1028
Query: 1576 GSKRRPQTPKEKAKALEDLAGFKELFQTPG------HTEE-SMTDDKITEVSCKSPQPDP 1628
+ + K E++ TP H E+ ++ ++KIT +S + P
Sbjct: 1029 SANEKTIPSPAKPTEHEEMTPSANENTTPSPVKPTEHGEKTTLANEKIT-LSPEGPTEHG 1087
Query: 1629 VKTPTSSKQRLKISLGKVGVKEE--VLPVGKLTQTSGKTTQTHRETAGDGKSI-----KA 1681
KT TS+ +++ SL K E P K+T ++ ++T+ HR+ A I +
Sbjct: 1088 AKT-TSANEKITPSLAKPTEHGERTTSPNDKITSSAAESTE-HRDRATSANVITPAPAEP 1145
Query: 1682 FKESAKQMLDPANYGTGMERWPRTPKEEAQSLEDLAGFKELFQTPDHTEESTTDDKTTKI 1741
K + + L E+ P++ + E E P E T K
Sbjct: 1146 IKHAKRTTLAHEKMTQVTEKSTEHPEKTTSTTEKTTRTPE---KPTLYSEKTICTKGKNT 1202
Query: 1742 ACKSPPPESMDTPTSTRRRPKTPLGKRDIVEELSALKQLTQTTHTDKVPGDE 1793
P E++ T T K P+ + E+ +A+ + + + KV GD+
Sbjct: 1203 PVPEKPTENLGNTTLTTETIKAPVKSTENPEKTAAVTKTIKP--SVKVTGDK 1252
Score = 57.4 bits (137), Expect = 2e-07
Identities = 215/1005 (21%), Positives = 343/1005 (34%), Gaps = 152/1005 (15%)
Query: 691 TTHTHREPAGDGKSIRTFKESPKQILDPAARVTGMKKWPRTPKEEAQSLEDLAGFKELFQ 750
T H R P + K+ + ES + + P +P E ++ E A
Sbjct: 400 TEHGERTPFANDKTTSSSAESTEH--GERTPLANENTTP-SPAEPTENRERTANENTTPS 456
Query: 751 TPGPSE--ESMTDEKTTKIACKSPPPESVDTPTSTKQWPKRSLRKADVEEEFLALRKLTP 808
GP+E E+ +EKTT + P E+ +T + K P + + + A K T
Sbjct: 457 PAGPTENRETTANEKTTLSPVE--PTENRETTANEKTTPSPAEPTENGQRTPFANEKTTS 514
Query: 809 SAGKAMLTPKPAGGDEKDIKAFMGTPVQKLDLAGTLPGSKRQLQTPKEKAQALEDLAGFK 868
S+ +P E+ TP+ ++ +P E
Sbjct: 515 SSA------EPTEHGER-------TPL----------ANENTTPSPAE------------ 539
Query: 869 ELFQTPGHTEELVAAGKTTKIPCDSPQSDPVDTPTSTKQRPKRSIRKADVEGELLACRNL 928
P E A KTT P + ++ D ++ S+ + G+ N
Sbjct: 540 -----PTENRERTANEKTTPSPAEPTENG--DRTPLANEKTTPSLAEPTENGQRTPFANE 592
Query: 929 MPSAGKAMHTPKPSVGEEKDIIIFVGTPVQKLDLTENLTGSKRRPQTPKEEAQALEDLTG 988
++ A +P+ EE+ TP+ EN T S P T E A E+ T
Sbjct: 593 KTTSSSA----EPTEHEER-------TPL----ANENTTPSPAEP-TENRERTANENTTP 636
Query: 989 FKELFQTPGHTEEAVAAGKTTKMPCESSPPESADTPTSTRRQPKTPLEKRDVQKELSALK 1048
P E A KTT P E + T P P E + Q+ A +
Sbjct: 637 SP---AGPTENREMTANEKTTLFPAEPTENRERTANEKTTSSPAEPTE--NGQRTPFANE 691
Query: 1049 KLTQTSGE-TTHTDKVPGGEDKSINAFRE-------TAKQKLDPAASVTGSKRHPKTKEK 1100
K T +S E T H ++ P + + + E TA +K P + R E
Sbjct: 692 KTTSSSAEPTEHGERTPLANENTTLSPAEPTENRERTANEKTTPFPAEPTENRERTANEN 751
Query: 1101 AQPLEDLAGLKELFQTPVCTDKPTTHEKTTKIACRSQPDPVDTPTSSKPQSKRSLRKVDV 1160
P T P +EKTT + TP +++ + S +
Sbjct: 752 TTP-------SPAQPTENGDRTPLANEKTTPSLAEPTENGKRTPFANEKTTSSSAEPTEH 804
Query: 1161 EEEFFALRKRTPSAGKAMHTPKPAVSGEKNIYAFMGTPVQKLDLTENLTGSKRRLQTPKE 1220
E + T S+ + + EK F P + + T N ++ P E
Sbjct: 805 AERTPLANENTTSSPAEPTENRERTANEKTT-QFPAEPTENRESTAN----EKTTPFPAE 859
Query: 1221 KAQALEDLAGFKELFQTRGHTE-ESMTNDKTAKVACKSSQP--DPDKNPASSKRRLKTSL 1277
+ E A TE E MT K ++P + ++ P ++++ +S
Sbjct: 860 PTENREWTANENTTLSPAEPTEHEEMTPLANEKTTLSPAEPTENGERTPFTNEKTTPSS- 918
Query: 1278 GKVGVKEELLAVGKLTQTSGE-TTHTHTEPTGDGKSMKAFMESPKQILDSAASLTGSKRQ 1336
E G+ T + E TT + EPT G ++I + A+ + +K
Sbjct: 919 ------AEPTEHGERTPLANEITTPSRAEPTEHG----------ERIANEKATPSPAK-- 960
Query: 1337 LRTPKGKSEVPEDLAGFIELFQTPSHTKESMTNEKTTKVSYRASQPDLVDTPTSSKPQPK 1396
T G++ V ED TPS + + E+T + + +PT S +
Sbjct: 961 -PTEHGETTVNED--------TTPSSAEPTENGERTP-----LANENTTTSPTESTEHGE 1006
Query: 1397 RSLRKADTEE--EFLAFRKQTPSAG-KAMHTP-KPAVGEEKDINTFLGT---PVQKLDQP 1449
R+ + T E ++TPSA K + +P KP EE + T PV+ +
Sbjct: 1007 RTANEKTTPSPAEPTEHGERTPSANEKTIPSPAKPTEHEEMTPSANENTTPSPVKPTEHG 1066
Query: 1450 GNLPGSNRRLQTRKEKAQALEELTGFRELFQTPCTDNPTT-DEKTTK---KILCKSPQS- 1504
+N ++ E T TP PT E+TT KI + +S
Sbjct: 1067 EKTTLANEKITLSPEGPTEHGAKTTSANEKITPSLAKPTEHGERTTSPNDKITSSAAEST 1126
Query: 1505 ---DPADTPTNTKQRPKRSLKKADVEEEFLAFRKLTPSAGKAM-HTPKAAVGEEKDINTF 1560
D A + P +K A + LA K+T K+ H K EK T
Sbjct: 1127 EHRDRATSANVITPAPAEPIKHA--KRTTLAHEKMTQVTEKSTEHPEKTTSTTEKTTRT- 1183
Query: 1561 VGTPVEKLDLLGNLPGSKRRPQTPKEKAKALEDLAGFKELFQTPGHTEESMTDDKITEVS 1620
EK L + TP + K E+L +T +S + + T
Sbjct: 1184 ----PEKPTLYSEKTICTKGKNTPVPE-KPTENLGNTTLTTETIKAPVKSTENPEKTAAV 1238
Query: 1621 CKSPQPDPVKTPTSSKQRLKISLGKVGVKEEVLPVGKLTQTSGKT 1665
K+ +P T S L K V +V P G T + +T
Sbjct: 1239 TKTIKPSVKVTGDKSLTTTSSHLNKTEVTHQV-PTGSFTLITSRT 1282
Score = 50.4 bits (119), Expect = 2e-05
Identities = 250/1287 (19%), Positives = 427/1287 (33%), Gaps = 142/1287 (11%)
Query: 94 SFRYENESLQNGRKSTEFPRKIREQEPARRVSRSSFSSDPDESEGIPLK-RRRVSFGGHL 152
S +++ L +G++ E P+ E R + + S D+ G + S H
Sbjct: 57 SIPFDHIVLHSGQRPPELPKSTEIHEQKRHCNTTRHSKPTDKPTGNSKTIDHKSSTDNHE 116
Query: 153 RPELFDENLPPNTPLKRGEAPTKRKSLVMHTPPVLKKIIKEQPQPSGKQESGSEIHVEVK 212
P +EN +G+ P R ++ + + +ES + H+
Sbjct: 117 APPTSEENSS-----NQGKDPMIRN----------QRSVDPADSTTTHKESAGKKHITPA 161
Query: 213 AQSLVISPPAPSPRKTPVA-SDQRRRSCKTAPASSSKSQTEVPKR--GGRKSGNLPSKRV 269
+S + + + + T SD+ R + + ++ K+ T K SGN +K+
Sbjct: 162 PKSKINCRKSTTGKSTVTRKSDKTGRPLEKSMSTLDKTSTSSHKTTTSFHNSGNSQTKQK 221
Query: 270 SISRSQHDILQMICSKRRSGASEANLIVAKSWADVVKLGAKQTQTKVIKHGPQR-SMNKR 328
S S + + + +G E + K+ + + + TK K+ + S N+
Sbjct: 222 STSFPEKITAASKTTYKTTGTPEES---EKTEDSRTTVASDKLLTKTTKNIQETISANEL 278
Query: 329 QRRPATPKKPVGEVHSQFSTGHANSPCTIIIGKAHTEKVHVPARPYRVLNNFISNQKMDF 388
+ A P + G ++ +T P A+ PA P + F
Sbjct: 279 TQSLAEPTEHGGRTANENNTPSPAEPTENRERTANENTTLSPAEPIENRERTANENTAPF 338
Query: 389 KEDLSGIAEMFKTPVKEQPQLTSTCHIAISNSENLLGKQFQGTDSGEE---------PLL 439
+ EM T H + +EN + T+ GE P
Sbjct: 339 PAGPTENREMTANENTTLFPAEPTEHGERTANENTTPSPAEPTEHGERTANENTTPSPAE 398
Query: 440 PTSESFGGNVFFSAQNAAKQPSDKCSASPPLRRQCIRENGNVAKTPRNTYKMTSLETKTS 499
PT ++ S + PL N N +P T +T+
Sbjct: 399 PTEHGERTPFANDKTTSSSAESTEHGERTPLA------NENTTPSPAEP---TENRERTA 449
Query: 500 DTETEPSKTVSTANRSGRSTEFRNIQKL-PVESKSEETNTEIVEC---ILKRGQKATLLQ 555
+ T PS T NR + E + + P E++ N + + GQ+
Sbjct: 450 NENTTPSPAGPTENRETTANEKTTLSPVEPTENRETTANEKTTPSPAEPTENGQRTPFAN 509
Query: 556 QRREGEMKEIERPFETYKENIELKENDEKMKA---MKRSRTWGQKCAPM-------SDLT 605
++ E P E + EN A R RT +K P D T
Sbjct: 510 EKTTSSSAE---PTEHGERTPLANENTTPSPAEPTENRERTANEKTTPSPAEPTENGDRT 566
Query: 606 DLKSLPDT-ELMKDTARGQN---LLQTQDHAKAPKSEKGKITKMPCQSLQPEPINTPTHT 661
L + T L + T GQ + + A +E + T + ++ P P PT
Sbjct: 567 PLANEKTTPSLAEPTENGQRTPFANEKTTSSSAEPTEHEERTPLANENTTPSPAE-PTEN 625
Query: 662 KQQL---KASLGKVGVKE--ELLAVGKFTRTSGETTHTHREPAGDGKSIRTFKESPKQIL 716
+++ + G E E+ A K T E T A + + SP +
Sbjct: 626 RERTANENTTPSPAGPTENREMTANEKTTLFPAEPTENRERTANEKTT-----SSPAEPT 680
Query: 717 DPAARVTGMKKWPRTPKEEAQSLE-----DLAGFKELFQTPGPSE--ESMTDEKTTKIAC 769
+ R + +T A+ E LA P+E E +EKTT
Sbjct: 681 ENGQRTPFANE--KTTSSSAEPTEHGERTPLANENTTLSPAEPTENRERTANEKTTPFPA 738
Query: 770 KSPPPESVDTPTSTKQWPKRSLRKADVEEEFLALRKLTPSAGKAMLTPKPAGGDEKDIKA 829
+ P E+ + + P + + + LA K TPS + K + +
Sbjct: 739 E--PTENRERTANENTTPSPAQPTENGDRTPLANEKTTPSLAEPTENGKRTPFANEKTTS 796
Query: 830 FMGTPVQKLDLAGTLPGSKRQLQTPKEKAQALEDLAGFK--ELFQTPGHTEELVAAGKTT 887
P + + T ++ +P E + E A K + P E A KTT
Sbjct: 797 SSAEPTEHAE--RTPLANENTTSSPAEPTENRERTANEKTTQFPAEPTENRESTANEKTT 854
Query: 888 KIPCDSPQSDPVDTPTSTKQRPKRSIRKADVEGELLACRNLMPSAGKAMHTPKPSVGEEK 947
P + ++ +T P ++ L P+ P E+
Sbjct: 855 PFPAEPTENREWTANENTTLSPAEPTEHEEMTPLANEKTTLSPAEPTENGERTPFTNEKT 914
Query: 948 DIIIFVGTP-VQKLDLTENLTGSKRRPQTPKEEAQALEDLTGFKELFQTPGH-TEEAVAA 1005
T ++ L +T R T E A E T +P TE
Sbjct: 915 TPSSAEPTEHGERTPLANEITTPSRAEPTEHGERIANEKAT------PSPAKPTEHGETT 968
Query: 1006 GKTTKMPCESSPPESAD-TPTSTRRQPKTPLEKRDVQKELSALKKLTQTSGE-TTHTDKV 1063
P + P E+ + TP + +P E + E +A +K T + E T H ++
Sbjct: 969 VNEDTTPSSAEPTENGERTPLANENTTTSPTESTE-HGERTANEKTTPSPAEPTEHGERT 1027
Query: 1064 PGGEDKSI-NAFRETAKQKLDPAASVTGSKRHPKTKEKAQPLEDLAGLKELFQTPVCTDK 1122
P +K+I + + T +++ P+A+ + K E + LA K + +
Sbjct: 1028 PSANEKTIPSPAKPTEHEEMTPSANENTTPSPVKPTEHGEK-TTLANEK----ITLSPEG 1082
Query: 1123 PTTHEKTTKIACRSQPDPVDTPT-----SSKPQSKRSLRKVDVEEEFFALRKRTPSAGKA 1177
PT H T A + PT ++ P K + + E R R SA
Sbjct: 1083 PTEHGAKTTSANEKITPSLAKPTEHGERTTSPNDKITSSAAESTEH----RDRATSANVI 1138
Query: 1178 MHTPKPAVSGEKNIYAFMGTPVQKLDLTENLTGSKRRLQTPKEKAQALEDLAGF--KELF 1235
P + K Q +TE T + + EK + ++
Sbjct: 1139 TPAPAEPIKHAKRTTLAHEKMTQ---VTEKSTEHPEKTTSTTEKTTRTPEKPTLYSEKTI 1195
Query: 1236 QTRGHT-------EESMTN----DKTAKVACKSSQPDPDKNPASSKRRLKTSLGKVGVKE 1284
T+G E++ N +T K KS++ +P+K A +K +K S+ G K
Sbjct: 1196 CTKGKNTPVPEKPTENLGNTTLTTETIKAPVKSTE-NPEKTAAVTK-TIKPSVKVTGDK- 1252
Query: 1285 ELLAVGKLTQTS---GETTHTHTEPTG 1308
LT TS +T TH PTG
Sbjct: 1253 ------SLTTTSSHLNKTEVTHQVPTG 1273
>gi|239740773 PREDICTED: similar to diffuse panbronchiolitis critical
region 1 [Homo sapiens]
Length = 1400
Score = 83.2 bits (204), Expect = 3e-15
Identities = 178/812 (21%), Positives = 295/812 (36%), Gaps = 109/812 (13%)
Query: 2133 EEPLAVSKLTRTSGETTQTHTEPTGDSKSIKAFKESPKQILDPAASVTGSRRQLRTRKEK 2192
++P+ ++ + ++T TH E G K +PK ++ S TG R +
Sbjct: 192 KDPMIRNQRSVDPADSTTTHKESAGK----KHITPAPKSKINCRKSTTGKSTVTRKSDKT 247
Query: 2193 ARALEDLVDFKELFSAPGH--------TEESMTIDKNTKIPCK--------------SPP 2230
R LE + + S H + S T K+T P K
Sbjct: 248 GRPLEKSMSTLDKTSTSSHKTTTSFHNSGNSQTKQKSTSFPEKITAASKTTYKTTGTPEE 307
Query: 2231 PELTDTATSTKRCPK--TRPRKEVKEELSAVERLTQT------SGQSTHTHKEPASGDEG 2282
E T+ + +T K T+ K ++E +SA E LTQ+ G T S E
Sbjct: 308 SEKTEDSRTTVASDKLLTKTTKNIQETISANE-LTQSLAEPTEHGGRTANENNTPSPAEP 366
Query: 2283 IKVLKQRAKKKPNPVEEEPSRRRPRAPKEKAQPLEDLAGFTELSETSGHTQESLTAGKAT 2342
+ ++ A + EP+ R R E P AG TE E + + +L
Sbjct: 367 TENRERTANENTTLSPAEPTENRERTANENTAPFP--AGPTENREMTANENTTL------ 418
Query: 2343 KIPCESPPLEVVDTTASTKRHLRTRVQKVQVKEEPSAVKFTQTSGETTD-ADKEPAGEDK 2401
P E P E + TA+ + + + + E + T + E T+ ++ P DK
Sbjct: 419 -FPAE--PTEHGERTAN-ENTTPSPAEPTEHGERTANENTTPSPAEPTEHGERTPFANDK 474
Query: 2402 GIKALKESAK---QTPAPAASVTGSRRRPRAPRESAQAIEDLAGFKDPAAGHTE--ESMT 2456
+ ES + +TP + T S P P E+ + + PA G TE E+
Sbjct: 475 TTSSSAESTEHGERTPLANENTTPS---PAEPTENRERTANENTTPSPA-GPTENRETTA 530
Query: 2457 DDKTTKIPCKSSPELEDTA----TSSKRRPRTRAQKVEVKEELLAVGKLTQTSGE-TTHT 2511
++KTT P + + E TA T S P Q+ E K T +S E T H
Sbjct: 531 NEKTTLSPVEPTENRETTANEKTTPSPAEPTENGQRTPFANE-----KTTSSSAEPTEHG 585
Query: 2512 DKEPVGEGKGTKAFKQPAKRKLDAEDVIGSRRQPRAPKEKAQPLE--DLASFQELSQTPG 2569
++ P+ T + +P + + E + P A+P E D TP
Sbjct: 586 ERTPLANENTTPSPAEPTENR---ERTANEKTTP----SPAEPTENGDRTPLANEKTTPS 638
Query: 2570 HTEELANGAADSFTSAPKQTPDSGKPLKISRRVLRAPKVEPVGDVVSTRDPVKSQSK-SN 2628
E NG F + K T S +P + R A + S +P +++ + +N
Sbjct: 639 LAEPTENGQRTPFAN-EKTTSSSAEPTEHEERTPLANE----NTTPSPAEPTENRERTAN 693
Query: 2629 TSLPPLPFKRGGGKDGSVTGTKRLRCMPAPEEIVEELPASKKQRVAPRARGKSSEPVVIM 2688
+ P P G ++ +T ++ PA E A++K +P +EP
Sbjct: 694 ENTTPSP--AGPTENREMTANEKTTLFPAEPTENRERTANEKTTSSP------AEPT--- 742
Query: 2689 KRSLRTSAKRIEPAEELNSNDMKTNKEEHKLQDSVPENKGISLRSRRQNKTEAEQQITEV 2748
+ +R A E ++ E + EN +S +N+ + T
Sbjct: 743 -----ENGQRTPFANEKTTSSSAEPTEHGERTPLANENTTLSPAGPTENRERTANEKTTP 797
Query: 2749 FVLAERIEINRNEKKPMKTSPEMDIQNPDDGARKPIPRDKVTEN-----KRCLRSARQNE 2803
F AE E NR T+P Q ++G R P+ +K T + + R+ NE
Sbjct: 798 FP-AEPTE-NRERTANENTTPS-PAQPTENGDRTPLANEKTTPSLAEPTENGKRTPFANE 854
Query: 2804 SSQPKVAEESGGQKSAKVLMQNQKGKGEAGNSDSMCLRSRKTKSQPAAST--LESKSVQR 2861
+ AE + + + +N + + KT PA T ES + ++
Sbjct: 855 KTTSSSAEPTEHAERTPLANENTTSSPAEPTENRERTANEKTTQFPAEPTENRESTANEK 914
Query: 2862 VTRSVKRCAENPK-KAEDNVCVKKIRTRSHRD 2892
T EN + A +N + H +
Sbjct: 915 TTPFPAEPTENREWTANENTTLSPAEPTEHEE 946
Score = 58.9 bits (141), Expect = 7e-08
Identities = 174/856 (20%), Positives = 296/856 (34%), Gaps = 109/856 (12%)
Query: 1081 KLDPAASVTGSKRHPKTKEKAQPLEDLAGLKELFQTPVCTDKPTTHEKTTKIACRSQPDP 1140
+L + + KRH T ++P TDKPT + KT I +S D
Sbjct: 135 ELPKSTEIHEQKRHCNTTRHSKP----------------TDKPTGNSKT--IDHKSSTDN 176
Query: 1141 VDTPTSSKPQSKRSLRKVDVEEEFFALRKRTPSAGKAMHTPKPAVSGEKNIYAFMGTPVQ 1200
+ P +S+ S + + + R P+ H +G+K+I P
Sbjct: 177 HEAPPTSEENSSNQGKDPMIRNQ----RSVDPADSTTTHKES---AGKKHITP---APKS 226
Query: 1201 KLDLTENLTGSKRRLQTPKEKAQALEDLAGFKELFQTRGH-TEESMTNDKTAKVACKSSQ 1259
K++ ++ TG + + + LE + T H T S N ++ KS+
Sbjct: 227 KINCRKSTTGKSTVTRKSDKTGRPLEKSMSTLDKTSTSSHKTTTSFHNSGNSQTKQKSTS 286
Query: 1260 PDPDKNPASSKRRLKTSLGKVGVKEELLAVGKLTQTSGETTHTHTEPTGDGKSMKAFMES 1319
P+K A+SK KT+ G EE S +T + T D K ++
Sbjct: 287 -FPEKITAASKTTYKTT----GTPEE----------SEKTEDSRTTVASD----KLLTKT 327
Query: 1320 PKQILD--SAASLTGSKRQLRTPKGKSEVPEDLAGFIELFQTPSHTKESMTNEKTT--KV 1375
K I + SA LT S + G++ + E P+ +E NE TT
Sbjct: 328 TKNIQETISANELTQSLAEPTEHGGRTANENNTPSPAE----PTENRERTANENTTLSPA 383
Query: 1376 SYRASQPDLVDTPTSSKPQPKRSLRKADTEEEFLAFRKQTPSAGKAM----HTPKPAV-- 1429
++ + T+ P R+ E F + G+ TP PA
Sbjct: 384 EPTENRERTANENTAPFPAGPTENREMTANENTTLFPAEPTEHGERTANENTTPSPAEPT 443
Query: 1430 --GEEKDINTFLGTPVQKLDQPGNLPGSNRRLQTRKEKAQALEELTGFRELFQTPCTDNP 1487
GE +P + + P +N + + ++ E T TP P
Sbjct: 444 EHGERTANENTTPSPAEPTEHGERTPFANDKTTSSSAESTEHGERTPLANENTTPSPAEP 503
Query: 1488 TTD-EKTTKKILCKSPQSDPADTPTNTKQRPKRSLKKADVEEEFLAFRKLTPSAGKAMHT 1546
T + E+T + SP + T ++ S + E A K TPS +
Sbjct: 504 TENRERTANENTTPSPAGPTENRETTANEKTTLSPVEPTENRETTANEKTTPSPAEPTEN 563
Query: 1547 PKAAVGEEKDINTFVGTPVEKLDLLGNLP-GSKRRPQTPKEKAKALEDLAGFKELFQTPG 1605
+ + + P E + P ++ +P E + E A K TP
Sbjct: 564 GQRTPFANEKTTSSSAEPTEHGE---RTPLANENTTPSPAEPTENRERTANEK---TTPS 617
Query: 1606 HTEESMTDDKI------TEVSCKSPQPDPVKTPTSSKQRLKISLGKVGVKEEV-LPVGKL 1658
E + D+ T S P + +TP ++++ S +E L
Sbjct: 618 PAEPTENGDRTPLANEKTTPSLAEPTENGQRTPFANEKTTSSSAEPTEHEERTPLANENT 677
Query: 1659 TQTSGKTTQTHRETAGDGKSIKAFKESAKQMLDPANYGTGMERWPRTPKEEAQSLEDLAG 1718
T + + T+ TA + + + + + T E+ P E ++ E A
Sbjct: 678 TPSPAEPTENRERTANENTTPSPAGPTENREM------TANEKTTLFPAEPTENRERTAN 731
Query: 1719 FKELFQTPDHTEEST----TDDKTTKIACKSPPPESMDTPTSTRRRPKTPLGKRDIVEEL 1774
K + TE ++KTT + + P TP + +P G + E
Sbjct: 732 EKTTSSPAEPTENGQRTPFANEKTTSSSAE-PTEHGERTPLANENTTLSPAGPTENRERT 790
Query: 1775 SALKQL---TQTTHTDKVPGDEDKGINVFRETAKQKLDPAAS--VTGSKRQPRTPKGKAQ 1829
+ K + T + +E+ + + T P A+ T S +P T GK
Sbjct: 791 ANEKTTPFPAEPTENRERTANENTTPSPAQPTENGDRTPLANEKTTPSLAEP-TENGKRT 849
Query: 1830 PLEDLAGLKELFQTPICTDKPTTHEKTTKIACRSPQPDPVGTPTIFKPQS---KRSLRKA 1886
P + +T + +PT H + T +A + P PT + ++ K + A
Sbjct: 850 PFAN-------EKTTSSSAEPTEHAERTPLANENTTSSP-AEPTENRERTANEKTTQFPA 901
Query: 1887 DVEE--ESLALRKRTP 1900
+ E ES A K TP
Sbjct: 902 EPTENRESTANEKTTP 917
Score = 51.6 bits (122), Expect = 1e-05
Identities = 113/540 (20%), Positives = 175/540 (32%), Gaps = 84/540 (15%)
Query: 964 ENLTGSKRRPQTPKEEAQALEDLTGFKELFQTPGHTEEAVAAGKTTKMPCESSPPESADT 1023
EN T S P E D T T +A TT P E +
Sbjct: 452 ENTTPSPAEPTEHGERTPFANDKTTSSSAESTEHGERTPLANENTTPSPAEPTENRERTA 511
Query: 1024 PTSTRRQPKTPLEKRDVQKELSALKKLTQTSGETTHTDKVPGGEDKSINAFRETAKQKLD 1083
+T P P E R+ T+ E T V E++ A +T
Sbjct: 512 NENTTPSPAGPTENRET------------TANEKTTLSPVEPTENRETTANEKTTP---S 556
Query: 1084 PAASVTGSKRHPKTKEKAQPLEDLAGLKELFQTPVCTDKPTTHEKTTKIACRSQPDPVDT 1143
PA +R P EK T + +PT H + T +A + T
Sbjct: 557 PAEPTENGQRTPFANEK---------------TTSSSAEPTEHGERTPLANEN-----TT 596
Query: 1144 PTSSKPQSKRSLRKVDVEEEFFALRKRTPSAGKAMHTPKPAVSGEKNIYAFMGTPVQKLD 1203
P+ ++P R E A K TPS +P +G++ A T +
Sbjct: 597 PSPAEPTENR---------ERTANEKTTPSPA------EPTENGDRTPLANEKTTPSLAE 641
Query: 1204 LTENLTGSKRRLQTPKEKAQAL-----EDLAGFKELFQTRGHTEESMTNDKTAKVACKSS 1258
TEN G + K + + E+ T E + ++TA S
Sbjct: 642 PTEN--GQRTPFANEKTTSSSAEPTEHEERTPLANENTTPSPAEPTENRERTANENTTPS 699
Query: 1259 QPDPDKNPASSKRRLKTSLGKVGVKEELLAVGKLTQTSGETTHTHTEPTGDGKSMKAFME 1318
P +N + KT+L E + + +TT + EPT +G+ E
Sbjct: 700 PAGPTENREMTANE-KTTLFPAEPTE-----NRERTANEKTTSSPAEPTENGQRTPFANE 753
Query: 1319 SPKQILDSAASLTGSKRQLRTPKGKSEVPEDLAGFIELFQTPSHTKESMTNEKTTKVSYR 1378
+++S ++ RTP AG P+ +E NEKTT
Sbjct: 754 K-----TTSSSAEPTEHGERTPLANENTTLSPAG-------PTENRERTANEKTTPFPAE 801
Query: 1379 ASQPDLVDTPTSSKPQPKRSLRKADTEEEFLAFRKQTPSAGKAMHTPKPAVGEEKDINTF 1438
++ ++ P P + D LA K TPS + K + +
Sbjct: 802 PTENRERTANENTTPSPAQPTENGDRTP--LANEKTTPSLAEPTENGKRTPFANEKTTSS 859
Query: 1439 LGTPVQKLDQPGNLPGSNRRLQTRKEKAQALEELTGFRELFQTPC--TDN--PTTDEKTT 1494
P + ++ P +N + + E T + Q P T+N T +EKTT
Sbjct: 860 SAEPTEHAER---TPLANENTTSSPAEPTENRERTANEKTTQFPAEPTENRESTANEKTT 916
Score = 45.8 bits (107), Expect = 6e-04
Identities = 240/1289 (18%), Positives = 419/1289 (32%), Gaps = 182/1289 (14%)
Query: 1241 TEESMTNDKTAKVACKSSQPDPDKNPASSKRRLKTSLGKVGVKEELLAVGKLTQTSGETT 1300
T++ N KT + KSS + + P S + ++ GK + + + + ++T
Sbjct: 158 TDKPTGNSKT--IDHKSSTDNHEAPPTSEEN--SSNQGK-----DPMIRNQRSVDPADST 208
Query: 1301 HTHTEPTGDGKSMKAFMESPKQILDSAASLTGSKRQLRTPKGKSEVPEDLAGFIELFQTP 1360
TH E G K +PK ++ S TG R E ++ T
Sbjct: 209 TTHKESAGK----KHITPAPKSKINCRKSTTGKSTVTRKSDKTGRPLEKSMSTLDKTSTS 264
Query: 1361 SH--------TKESMTNEKTTKVSYRASQPDLVDTPTSSKPQPKRSLRKADTEEEFLAFR 1412
SH + S T +K+T + + T+ P+ E E
Sbjct: 265 SHKTTTSFHNSGNSQTKQKSTSFPEKITAASKTTYKTTGTPE----------ESEKTEDS 314
Query: 1413 KQTPSAGKAMHTPKPAVGEEKDINTFLGTPVQKLDQPGNLPGSNRRLQTRKEKAQALEEL 1472
+ T ++ K + + E N + + + G N
Sbjct: 315 RTTVASDKLLTKTTKNIQETISANELTQSLAEPTEHGGRTANENN--------------- 359
Query: 1473 TGFRELFQTPCTDNPTTD-EKTTKKILCKSPQSDPADTPTNTKQRPKRSLKKADVEEEFL 1531
TP PT + E+T + SP ++P + T E
Sbjct: 360 --------TPSPAEPTENRERTANENTTLSP-AEPTENRERTANENTAPFPAGPTEN--- 407
Query: 1532 AFRKLTPSAGKAMHTPKAAVGEEKDIN-TFVGTPVEKLDLLGNLPGSKRRPQTPKEKAKA 1590
R++T + + + E+ N +P E + G ++ +P E +
Sbjct: 408 --REMTANENTTLFPAEPTEHGERTANENTTPSPAEPTEH-GERTANENTTPSPAEPTEH 464
Query: 1591 LEDLAGFKELFQTPGHTEESMTDDKITEVSCKSPQPDPVKTPTSSKQRL---KISLGKVG 1647
E + +T + ES + T ++ ++ P P + PT +++R + G
Sbjct: 465 GERTPFAND--KTTSSSAESTEHGERTPLANENTTPSPAE-PTENRERTANENTTPSPAG 521
Query: 1648 VKEE----------VLPV----GKLTQTSGKTTQTHRETAGDGKSIK-AFKESAKQMLDP 1692
E + PV + T + KTT + E +G+ A +++ +P
Sbjct: 522 PTENRETTANEKTTLSPVEPTENRETTANEKTTPSPAEPTENGQRTPFANEKTTSSSAEP 581
Query: 1693 ANYGT----GMERWPRTPKEEAQSLEDLAGFKELFQTPDHTEESTTDDKTTKIACKSPPP 1748
+G E +P E ++ E A K TP E + D+T K+ P
Sbjct: 582 TEHGERTPLANENTTPSPAEPTENRERTANEKT---TPSPAEPTENGDRTPLANEKTTP- 637
Query: 1749 ESMDTPTSTRRRPKTPLGKRDIVEELSALKQLTQTTHTDKVPGDEDKGINVFRETAKQKL 1808
S+ PT +R TP E + T H ++ P + T
Sbjct: 638 -SLAEPTENGQR--TPFAN-----EKTTSSSAEPTEHEERTPLANEN-------TTPSPA 682
Query: 1809 DPAASV--TGSKRQPRTPKGKAQPLEDLAGLKE-LFQT-PICTDKPTTHEKTTKIACRSP 1864
+P + T ++ +P G + E A K LF P + T +EKTT SP
Sbjct: 683 EPTENRERTANENTTPSPAGPTENREMTANEKTTLFPAEPTENRERTANEKTTS----SP 738
Query: 1865 -QPDPVGTPTIFKPQSKRSLRKADVEEESLALRKRTPSVGKAMDTPKPAGGDEKDMKAFM 1923
+P G T F + S E +RTP + T PAG E +
Sbjct: 739 AEPTENGQRTPFANEKTTSSSAEPTEHG-----ERTP-LANENTTLSPAGPTENRERT-- 790
Query: 1924 GTPVQKLDLPGNLPGSKRWPQTPKEKAQALEDLAGFKELFQTPGTDKPTTDEKTTKIACK 1983
+++ P E + E A TP +PT + T +A +
Sbjct: 791 --------------ANEKTTPFPAEPTENRERTANENT---TPSPAQPTENGDRTPLANE 833
Query: 1984 SPQPDPVDTPASTKQRPKRNLRKADVEEEFLALRKRTPSAGKAMDTPKPAVSDEKNINTF 2043
P + + K+ P N + E +RTP A + T PA E T
Sbjct: 834 KTTPSLAEPTENGKRTPFANEKTTSSSAEPTEHAERTPLANE-NTTSSPAEPTENRERT- 891
Query: 2044 VETPVQKLDLLGNLPGSKRQPQTPKEKAEALEDLVGFKEL-FQTPGHTEESMTDDKITEV 2102
+++ Q P E E E K F T ++ T +
Sbjct: 892 ---------------ANEKTTQFPAEPTENRESTANEKTTPFPAEPTENREWTANENTTL 936
Query: 2103 SCKSPQPESFKTSRSSKQRLKIPLVKVDMKEEPLAV-SKLTRTSGETTQTHTE-PTGDSK 2160
S P T + L+ P + E P + + + T+G + T +E T +
Sbjct: 937 SPAEPTEHEEMTPLMVDENLQAPFRQGSCAERPKDICATVASTTGSESSTASEIITSSTM 996
Query: 2161 SIKAFKESPKQILDPAASVTGSRRQLRTRKEKARALEDLVDFKELFSAPGHTEESMTIDK 2220
S+ A S A+ +T S + + + + F S P T + ++
Sbjct: 997 SVSATASSTAS--STASEITMSSAAIPV----SSTAYETIRFSTAVSEP-VTASILALES 1049
Query: 2221 NTKIPCKSPPPELTDTATSTKRCPKTRPRKEVKEELSAVERLTQTSGQSTHTHKEPASGD 2280
S T T+++ P T K + +++T+ + T E +
Sbjct: 1050 TLAFTTVSN----TTTSSTVTSVPTTASTSGSKNTTACEATMSETT-IAAITASEDTTVS 1104
Query: 2281 EGIKVLKQRAKKKPNPVEEEPSRRRPRAPKEKAQPLEDLAGFTELSETSGHT-QESLTAG 2339
V+ A+ P+ + P+ + L+ T T+ +T +++T
Sbjct: 1105 TQTSVI--AAESVPHTATKTPTDTTTASVSATVPKNNTLSVITSTPSTAPNTASKTMTTA 1162
Query: 2340 KATKIPCESPPLEVVDTTASTKRHLRTRVQKVQVKEEPSAVKFTQTSGETTDADKEPAGE 2399
T L T ++K + + + + T+ SG T ++ A
Sbjct: 1163 SKTTTTSTITSLPTTVFTTTSKITAGSEIPTASTTDSATTAISTKASGTTVESAPSTAPP 1222
Query: 2400 DKGIKALKESAKQTPAPAASVTGSRRRPRAPRE-SAQAIEDLAGFKDPAAGHTEESMTDD 2458
T + TG P A A E G + A + +T
Sbjct: 1223 TPAETTTASVPTTTSTTGSENTGHHTVSSVPTTVFATASESSTGSETTRASTSATEVTTA 1282
Query: 2459 KTTKIPCKSSPELEDTATSSKRRPRTRAQ 2487
TT + S +TA S + P T Q
Sbjct: 1283 MTTAMTTGS-----ETAVVSTKAPVTTTQ 1306
Score = 45.8 bits (107), Expect = 6e-04
Identities = 169/861 (19%), Positives = 278/861 (32%), Gaps = 152/861 (17%)
Query: 691 TTHTHREPAGDGKSIRTFKESPKQILDPAARVTGMKKWPRTPKEEAQSLEDLAGFKELFQ 750
T H R P + K+ + ES + + P +P E ++ E A
Sbjct: 462 TEHGERTPFANDKTTSSSAESTEH--GERTPLANENTTP-SPAEPTENRERTANENTTPS 518
Query: 751 TPGPSE--ESMTDEKTTKIACKSPPPESVDTPTSTKQWPKRSLRKADVEEEFLALRKLTP 808
GP+E E+ +EKTT + P E+ +T + K P + + + A K T
Sbjct: 519 PAGPTENRETTANEKTTLSPVE--PTENRETTANEKTTPSPAEPTENGQRTPFANEKTTS 576
Query: 809 SAGKAMLTPKPAGGDEKDIKAFMGTPVQKLDLAGTLPGSKRQLQTPKEKAQALEDLAGFK 868
S+ +P E+ TP+ ++ +P E
Sbjct: 577 SSA------EPTEHGER-------TPL----------ANENTTPSPAE------------ 601
Query: 869 ELFQTPGHTEELVAAGKTTKIPCDSPQSDPVDTPTSTKQRPKRSIRKADVEGELLACRNL 928
P E A KTT P + ++ D ++ S+ + G+ N
Sbjct: 602 -----PTENRERTANEKTTPSPAEPTENG--DRTPLANEKTTPSLAEPTENGQRTPFANE 654
Query: 929 MPSAGKAMHTPKPSVGEEKDIIIFVGTPVQKLDLTENLTGSKRRPQTPKEEAQALEDLTG 988
++ A +P+ EE+ TP+ EN T S P T E A E+ T
Sbjct: 655 KTTSSSA----EPTEHEER-------TPL----ANENTTPSPAEP-TENRERTANENTTP 698
Query: 989 FKELFQTPGHTEEAVAAGKTTKMPCESSPPESADTPTSTRRQPKTPLEKRDVQKELSALK 1048
P E A KTT P E + T P P E + Q+ A +
Sbjct: 699 SP---AGPTENREMTANEKTTLFPAEPTENRERTANEKTTSSPAEPTE--NGQRTPFANE 753
Query: 1049 KLTQTSGE-TTHTDKVPGGEDKSINAFRETAKQKLDPAASVTGSKRHPKTKEKAQPLEDL 1107
K T +S E T H ++ P + + L PA +R K P E
Sbjct: 754 KTTSSSAEPTEHGERTPLANENT----------TLSPAGPTENRERTANEKTTPFPAE-- 801
Query: 1108 AGLKELFQTPVCTDKPTTHEKTTKIACRSQPDPVDTPTSSKPQSKRSLRKVDVEEEFFAL 1167
P + T +E TT + + TP +++ + +
Sbjct: 802 ---------PTENRERTANENTTPSPAQPTENGDRTPLANEKTTPSLAEPTE-------N 845
Query: 1168 RKRTPSAGK--AMHTPKPAVSGEKNIYAFMGTPVQKLDLTEN--LTGSKRRLQTPKEKAQ 1223
KRTP A + + +P E+ A T + TEN T +++ Q P E +
Sbjct: 846 GKRTPFANEKTTSSSAEPTEHAERTPLANENTTSSPAEPTENRERTANEKTTQFPAEPTE 905
Query: 1224 ALEDLAGFKELFQTRGHTEESMTNDKTAKVACKSSQPDPDKNPASSKRRLKTSL------ 1277
E A K T E + + TA S +P ++ + + +L
Sbjct: 906 NRESTANEK---TTPFPAEPTENREWTANENTTLSPAEPTEHEEMTPLMVDENLQAPFRQ 962
Query: 1278 GKVGVKEELLAVGKLTQTSGETTHTHTEPTGDGKSMKAFMES-----PKQILDSAASLTG 1332
G + + + + T E++ T S+ A S +I S+A++
Sbjct: 963 GSCAERPKDICATVASTTGSESSTASEIITSSTMSVSATASSTASSTASEITMSSAAIPV 1022
Query: 1333 SKRQLRTPKGKSEVPEDL-AGFIELFQTPSHTKESMTNEKTTKVSYRASQPDLVDTPTSS 1391
S T + + V E + A + L T + T S T +T S PT++
Sbjct: 1023 SSTAYETIRFSTAVSEPVTASILALESTLAFTTVSNTTTSSTVTS----------VPTTA 1072
Query: 1392 KPQPKRSLRKADTEEEFLAFRKQTPSAGKAMHTPKPAVGEEKDINTFLGTPVQK------ 1445
++ + T S + T + E +T TP
Sbjct: 1073 STSGSKNTTACEATMSETTIAAITASEDTTVSTQTSVIAAESVPHTATKTPTDTTTASVS 1132
Query: 1446 ------------LDQPGNLPGSNRRLQTRKEKAQALEELTGFRELFQTPCTDNPTTDEKT 1493
P P + + T K +T P T TT + T
Sbjct: 1133 ATVPKNNTLSVITSTPSTAPNTASKTMTTASKTTTTSTITSL------PTTVFTTTSKIT 1186
Query: 1494 TKKILCKSPQSDPADTPTNTK 1514
+ + +D A T +TK
Sbjct: 1187 AGSEIPTASTTDSATTAISTK 1207
Score = 40.0 bits (92), Expect = 0.033
Identities = 189/961 (19%), Positives = 308/961 (32%), Gaps = 111/961 (11%)
Query: 497 KTSDTETEPSKTVSTANRSGRSTEFRNIQKL-PVESKSEETN----------TEIVECIL 545
+T++ PS T NR + E + P E++ N TE E
Sbjct: 353 RTANENNTPSPAEPTENRERTANENTTLSPAEPTENRERTANENTAPFPAGPTENREMTA 412
Query: 546 KRGQKATLLQQRREGEMKEIERPFETYKENIELKE---NDEKMKAMKRSRTWGQKCAPMS 602
+ GE E + E E E N+ + G++ +
Sbjct: 413 NENTTLFPAEPTEHGERTANENTTPSPAEPTEHGERTANENTTPSPAEPTEHGERTPFAN 472
Query: 603 DLTDLKSLPDTELMKDTARGQNLLQTQDHAKAPKSEKGKITKMPCQSLQPEPINTPTHTK 662
D T S TE + T L ++ +P + ++ P P PT +
Sbjct: 473 DKTTSSSAESTEHGERTP-----LANENTTPSPAEPTENRERTANENTTPSPAG-PTENR 526
Query: 663 QQL---KASLGKVGVKEELLAVGKFTRTSGETTHTHREPAGDGKSIRTFKESPKQILDPA 719
+ K +L V E + T + +TT + EP +G+ RT + K A
Sbjct: 527 ETTANEKTTLSPVEPTEN-----RETTANEKTTPSPAEPTENGQ--RTPFANEKTTSSSA 579
Query: 720 ARVTGMKKWPR-------TPKEEAQSLEDLAGFKELFQTPGPSEES-------MTDEKTT 765
++ P +P E ++ E A K TP P+E + + +EKTT
Sbjct: 580 EPTEHGERTPLANENTTPSPAEPTENRERTANEKT---TPSPAEPTENGDRTPLANEKTT 636
Query: 766 KIACKSPPPESVDTPTSTKQWPKRSLRKADVEEEF-LALRKLTPSAGKAM---------- 814
+ P TP + ++ S + EE LA TPS +
Sbjct: 637 P-SLAEPTENGQRTPFANEKTTSSSAEPTEHEERTPLANENTTPSPAEPTENRERTANEN 695
Query: 815 LTPKPAGGDEKDIKAFMGTPVQKLDLAGTLPGSKRQL----QTPKEKAQALEDLAGFKEL 870
TP PAG E T +K L P R+ +T A+ E+ G +
Sbjct: 696 TTPSPAGPTENREM----TANEKTTLFPAEPTENRERTANEKTTSSPAEPTEN--GQRTP 749
Query: 871 F---QTPGHTEELVAAGKTTKIPCDSPQSDPVDTPTSTKQRPKRSIR-----KADVEGEL 922
F +T + E G+ T + ++ P PT ++R + E
Sbjct: 750 FANEKTTSSSAEPTEHGERTPLANENTTLSPAG-PTENRERTANEKTTPFPAEPTENRER 808
Query: 923 LACRNLMPSAGKAMHTPKPSVGEEKDIIIFVGTPVQKLDLT----ENLTGSKRRPQTPKE 978
A N PS + + + + P + T E T S P E
Sbjct: 809 TANENTTPSPAQPTENGDRTPLANEKTTPSLAEPTENGKRTPFANEKTTSSSAEPTEHAE 868
Query: 979 EAQALEDLTGFKELFQTPGHTEEAVAAGKTTKMPCESSPPESADTPTSTRRQPKTPLEKR 1038
+ T P E A KTT+ P E + + T P P E R
Sbjct: 869 RTPLANENTTSSPA--EPTENRERTANEKTTQFPAEPTENRESTANEKTTPFPAEPTENR 926
Query: 1039 DVQKELSALKKLTQTSGE-TTHTDKVPGGEDKSINA-FR-----ETAKQKLDPAASVTGS 1091
E +A + T + E T H + P D+++ A FR E K AS TGS
Sbjct: 927 ----EWTANENTTLSPAEPTEHEEMTPLMVDENLQAPFRQGSCAERPKDICATVASTTGS 982
Query: 1092 KRHPKTKEKAQPLEDLAGLKELFQTPVCTDKPTTHEKTTKIACRSQPDPVDTPTSSKPQS 1151
+ T + ++ T T T + + + T+
Sbjct: 983 E--SSTASEIITSSTMSVSATASSTASSTASEITMSSAAIPVSSTAYETIRFSTAVSEPV 1040
Query: 1152 KRSLRKVDVEEEFFALRKRTPSAGKAMHTPKPAVSGEKNIYA----FMGTPVQKLDLTEN 1207
S+ ++ F + T S+ + SG KN A T + + +E+
Sbjct: 1041 TASILALESTLAFTTVSNTTTSSTVTSVPTTASTSGSKNTTACEATMSETTIAAITASED 1100
Query: 1208 LTGSKRRLQTPKEKAQALEDLAGFKELFQTRGHTEESMTNDKTAKVACKSSQPDPD---K 1264
T S QT A+++ A T ++ + T V + P+ K
Sbjct: 1101 TTVS---TQTSVIAAESVPHTATKTPTDTTTASVSATVPKNNTLSVITSTPSTAPNTASK 1157
Query: 1265 NPASSKRRLKTSLGKVGVKEELLAVGKLTQTSGETTHTHTEPTGDGKSMKAFMESPKQIL 1324
++ + TS K+T S T + T+ S KA + +
Sbjct: 1158 TMTTASKTTTTSTITSLPTTVFTTTSKITAGSEIPTASTTDSATTAISTKASGTTVESAP 1217
Query: 1325 DSAASLTGSKRQLRTPKGKSEVPEDLAGFIELFQTP----SHTKESMTNEKTTKVSYRAS 1380
+A P S + G + P + ES T +TT+ S A+
Sbjct: 1218 STAPPTPAETTTASVPTTTSTTGSENTGHHTVSSVPTTVFATASESSTGSETTRASTSAT 1277
Query: 1381 Q 1381
+
Sbjct: 1278 E 1278
Score = 37.7 bits (86), Expect = 0.17
Identities = 160/849 (18%), Positives = 280/849 (32%), Gaps = 88/849 (10%)
Query: 94 SFRYENESLQNGRKSTEFPRKIREQEPARRVSRSSFSSDPDESEGIPLK-RRRVSFGGHL 152
S +++ L +G++ E P+ E R + + S D+ G + S H
Sbjct: 119 SIPFDHIVLHSGQRPPELPKSTEIHEQKRHCNTTRHSKPTDKPTGNSKTIDHKSSTDNHE 178
Query: 153 RPELFDENLPPNTPLKRGEAPTKRKSLVMHTPPVLKKIIKEQPQPSGKQESGSEIHVEVK 212
P +EN +G+ P R ++ + + +ES + H+
Sbjct: 179 APPTSEENSS-----NQGKDPMIRN----------QRSVDPADSTTTHKESAGKKHITPA 223
Query: 213 AQSLVISPPAPSPRKTPVA-SDQRRRSCKTAPASSSKSQTEVPKR--GGRKSGNLPSKRV 269
+S + + + + T SD+ R + + ++ K+ T K SGN +K+
Sbjct: 224 PKSKINCRKSTTGKSTVTRKSDKTGRPLEKSMSTLDKTSTSSHKTTTSFHNSGNSQTKQK 283
Query: 270 SISRSQHDILQMICSKRRSGASEANLIVAKSWADVVKLGAKQTQTKVIKHGPQR-SMNKR 328
S S + + + +G E + K+ + + + TK K+ + S N+
Sbjct: 284 STSFPEKITAASKTTYKTTGTPEES---EKTEDSRTTVASDKLLTKTTKNIQETISANEL 340
Query: 329 QRRPATPKKPVGEVHSQFSTGHANSPCTIIIGKAHTEKVHVPARPYRVLNNFISNQKMDF 388
+ A P + G ++ +T P A+ PA P + F
Sbjct: 341 TQSLAEPTEHGGRTANENNTPSPAEPTENRERTANENTTLSPAEPTENRERTANENTAPF 400
Query: 389 KEDLSGIAEMFKTPVKEQPQLTSTCHIAISNSENLLGKQFQGTDSGEE---------PLL 439
+ EM T H + +EN + T+ GE P
Sbjct: 401 PAGPTENREMTANENTTLFPAEPTEHGERTANENTTPSPAEPTEHGERTANENTTPSPAE 460
Query: 440 PTSESFGGNVFFSAQNAAKQPSDKCSASPPLRRQCIRENGNVAKTPRNTYKMTSLETKTS 499
PT ++ S + PL N N +P T +T+
Sbjct: 461 PTEHGERTPFANDKTTSSSAESTEHGERTPLA------NENTTPSPAEP---TENRERTA 511
Query: 500 DTETEPSKTVSTANRSGRSTEFRNIQKL-PVESKSEETNTEIVEC---ILKRGQKATLLQ 555
+ T PS T NR + E + + P E++ N + + GQ+
Sbjct: 512 NENTTPSPAGPTENRETTANEKTTLSPVEPTENRETTANEKTTPSPAEPTENGQRTPFAN 571
Query: 556 QRREGEMKEIERPFETYKENIELKENDEKMKA---MKRSRTWGQKCAPM-------SDLT 605
++ E P E + EN A R RT +K P D T
Sbjct: 572 EKTTSSSAE---PTEHGERTPLANENTTPSPAEPTENRERTANEKTTPSPAEPTENGDRT 628
Query: 606 DLKSLPDT-ELMKDTARGQN---LLQTQDHAKAPKSEKGKITKMPCQSLQPEPINTPTHT 661
L + T L + T GQ + + A +E + T + ++ P P PT
Sbjct: 629 PLANEKTTPSLAEPTENGQRTPFANEKTTSSSAEPTEHEERTPLANENTTPSPAE-PTEN 687
Query: 662 KQQL---KASLGKVGVKE--ELLAVGKFTRTSGETTHTHREPAGDGKSIRTFKESPKQIL 716
+++ + G E E+ A K T E T A + + SP +
Sbjct: 688 RERTANENTTPSPAGPTENREMTANEKTTLFPAEPTENRERTANEKTT-----SSPAEPT 742
Query: 717 DPAARVTGMKKWPRTPKEEAQSLE-----DLAGFKELFQTPGPSE--ESMTDEKTTKIAC 769
+ R + +T A+ E LA GP+E E +EKTT
Sbjct: 743 ENGQRTPFANE--KTTSSSAEPTEHGERTPLANENTTLSPAGPTENRERTANEKTTPFPA 800
Query: 770 KSPPPESVDTPTSTKQWPKRSLRKADVEEEFLALRKLTPSAGKAMLTPKPAGGDEKDIKA 829
+ P E+ + + P + + + LA K TPS + K + +
Sbjct: 801 E--PTENRERTANENTTPSPAQPTENGDRTPLANEKTTPSLAEPTENGKRTPFANEKTTS 858
Query: 830 FMGTPVQKLDLAGTLPGSKRQLQTPKEKAQALEDLAGFK--ELFQTPGHTEELVAAGKTT 887
P + + T ++ +P E + E A K + P E A KTT
Sbjct: 859 SSAEPTEHAE--RTPLANENTTSSPAEPTENRERTANEKTTQFPAEPTENRESTANEKTT 916
Query: 888 KIPCDSPQS 896
P + ++
Sbjct: 917 PFPAEPTEN 925
Score = 36.2 bits (82), Expect = 0.48
Identities = 124/659 (18%), Positives = 203/659 (30%), Gaps = 104/659 (15%)
Query: 751 TPGPSEESMTDEKTTKIACKSPPPESVDTPTSTKQWPKRSLRKADVEEEFLALRKLTPSA 810
TP P+E + E+T P E + T E R++T +
Sbjct: 360 TPSPAEPTENRERTANENTTLSPAEPTENRERTANENTAPFPAGPTEN-----REMTANE 414
Query: 811 GKAMLTPKPAGGDEKDIKAFMGTPVQKLDLAGTLPGSKRQLQTPKEKAQALEDLAGFKEL 870
+ +P E+ + G ++ +P E + E +
Sbjct: 415 NTTLFPAEPTEHGERTANENTTPSPAEPTEHGERTANENTTPSPAEPTEHGERTPFAND- 473
Query: 871 FQTPGHTEELVAAGKTTKIPCDSPQSDPVDTPTSTKQRPKRSIRKADVEGELLACRNLMP 930
+T + E G+ T + ++ P + PT ++R A N P
Sbjct: 474 -KTTSSSAESTEHGERTPLANENTTPSPAE-PTENRERT--------------ANENTTP 517
Query: 931 SAGKAMHTPKPSVGEEKDIIIFVGTPVQKLDLTENLTGSKRRPQTPKEEAQALEDLTGFK 990
S + + E+ + T ++ E T S P + + T
Sbjct: 518 SPAGPTENRETTANEKTTLSPVEPTENRETTANEKTTPSPAEPTENGQRTPFANEKTTSS 577
Query: 991 ELFQTPGHTEEAVAAGKTTKMPCESSPPESADTPTSTRRQPKTPLEKRDVQKELSALKKL 1050
T +A TT P E + T P P E D + L+ K
Sbjct: 578 SAEPTEHGERTPLANENTTPSPAEPTENRERTANEKTTPSPAEPTENGD-RTPLANEKTT 636
Query: 1051 TQTSGETTHTDKVPGGEDKSINAFRE-TAKQKLDPAASVTGSKRHPKTKEKAQPLEDLAG 1109
+ T + + P +K+ ++ E T ++ P A+ T A+P E+
Sbjct: 637 PSLAEPTENGQRTPFANEKTTSSSAEPTEHEERTPLAN------ENTTPSPAEPTENRER 690
Query: 1110 LKELFQT-----PVCTDKPTTHEKTTKIACRSQPDPVDTPTSSKPQSKRSLRKVDVEEEF 1164
T P + T +EKTT + T + K S + + +
Sbjct: 691 TANENTTPSPAGPTENREMTANEKTTLFPAEPTENRERT-ANEKTTSSPAEPTENGQRTP 749
Query: 1165 FALRKRTPSAGKAMHTPKPAVSGEKNIYAFMGTPVQKLDLTENLTGSKRRLQTPKEKAQA 1224
FA K T S+ +P GE+ A T + TEN R +T EK
Sbjct: 750 FANEKTTSSSA------EPTEHGERTPLANENTTLSPAGPTEN------RERTANEKT-- 795
Query: 1225 LEDLAGFKELFQTRGHTEESMTNDKTAKVACKSSQPDPDKNPASSKRRLKTSLGKVGVKE 1284
T E + ++TA S P +N
Sbjct: 796 ------------TPFPAEPTENRERTANENTTPSPAQPTEN------------------- 824
Query: 1285 ELLAVGKLTQTSGE-TTHTHTEPTGDGKSMKAFMESPKQILDSAASLTGSKRQLRTPKGK 1343
G T + E TT + EPT +GK E +++S ++ RTP
Sbjct: 825 -----GDRTPLANEKTTPSLAEPTENGKRTPFANEK-----TTSSSAEPTEHAERTPLAN 874
Query: 1344 SEVPEDLAGFIELFQTPSHTKESMTNEKTTK-----VSYRASQPDLVDTPTSSKPQPKR 1397
A P+ +E NEKTT+ R S + TP ++P R
Sbjct: 875 ENTTSSPA-------EPTENRERTANEKTTQFPAEPTENRESTANEKTTPFPAEPTENR 926
>gi|91982772 mucin 17 [Homo sapiens]
Length = 4493
Score = 78.2 bits (191), Expect = 1e-13
Identities = 335/1701 (19%), Positives = 539/1701 (31%), Gaps = 224/1701 (13%)
Query: 1020 SADTP--TSTRRQPKTPLEKRDVQKELSALKKLTQTSGETTHTDKVPGGED--------- 1068
++DTP +STR TP E R + S L +S E T + P G D
Sbjct: 99 TSDTPGVSSTRM---TPTESRTTSESTSDSTTLFPSSTEDTSSPTTPEGTDVPMSTPSEE 155
Query: 1069 --KSINAFRETAK-----------QKLD---PAASVTGSKRHPKTKEKAQ--PLEDLAGL 1110
S AF TA K+D P + T + P T E + G
Sbjct: 156 SISSTMAFVSTAPLPSFEAYTSLTYKVDMSTPLTTSTQASSSPTTPESTTIPKSTNSEGS 215
Query: 1111 KELFQTPVCTDKPTTHEKTTKIACRSQPDPVDTPTSSKPQSKRSLRKVDVEEEFFALRKR 1170
L P T K + E T + + P + TP + Q+ S E +L
Sbjct: 216 TPLTSMPASTMKVASSEAITLL---TTPVEISTPVTISAQASSS----PTTAEGPSLSNS 268
Query: 1171 TPSAGKAMHTPKP-----AVSGEKNIYAFM--GTPVQKLDLTE------NLTGSKRRLQT 1217
PS G T P VS E + + T + + TE G+ T
Sbjct: 269 APSGGSTPLTRMPLSVMLVVSSEASTLSTTPAATNIPVITSTEASSSPTTAEGTSIPTST 328
Query: 1218 PKEKAQALEDLAGFKELFQTRGHTEESMTNDKTAKVACKSSQPDPDKNPASSKRRLKTSL 1277
E + L T + S+T T+ + S++P A + L ++L
Sbjct: 329 YTEGSTPLTSTPASTMPVATSEMSTLSITPVDTSTLVTTSTEPSSLPTTAEATSMLTSTL 388
Query: 1278 GKVGVKEELLAVGKLTQTSGETTHTHTEPTGDGKSMKAFME---SPKQILDSAASLT--- 1331
+ + V + S E + T T P + E SP D++ + +
Sbjct: 389 SEGSTPLTNMPVSTILVASSEASTTSTIPVDSKTFVTTASEASSSPTTAEDTSIATSTPS 448
Query: 1332 -GSKRQLRTPKGKSEVPEDLAGFIELFQTPSHTKESMTNEKTTKVSYRASQPDLVDTPTS 1390
GS P + V A L TP +K +T +T+ S ++ PTS
Sbjct: 449 EGSTPLTSMPVSTTPVASSEAS--NLSTTPVDSKTQVTT--STEASSSPPTAEVNSMPTS 504
Query: 1391 SKPQPKRSLRKADTEEEFLAFRKQTPSAGKAMHTPKPAVGEEKDINTFLGTPVQKLDQPG 1450
+ + L +A + + + + T P + ++ T + P
Sbjct: 505 TPSEGSTPLTSMSVSTMPVASSEASTLSTTPVDTSTPVTTSSEASSS--STTPEGTSIPT 562
Query: 1451 NLPGSNRRLQTRKEKAQALEELTGFRELFQTPCTDNPTTDEKTTKKILCKSPQSDPADTP 1510
+ P T + L + TP N T T+ + S ++ P
Sbjct: 563 STPSEGSTPLTNMPVSTRLVVSSEASTTSTTPADSN--TFVTTSSEASSSSTTAEGTSMP 620
Query: 1511 TNTKQRPKRSLKKADVEEEFLAFRKLTPSAGKAMHTPKAAVGEEKDINTFVGTPVEKLDL 1570
T+T ++ V +A + A TP D NT V T E
Sbjct: 621 TSTYSERGTTITSMSVSTTLVA----SSEASTLSTTPV-------DSNTPVTTSTEATSS 669
Query: 1571 LGNLPGSKRRPQTPKEKAKALEDL---------AGFKELFQTPGHTEESMTDDKITEVSC 1621
G+ T E + L + + L TP T +T TE S
Sbjct: 670 STTAEGTSMPTSTYTEGSTPLTSMPVNTTLVASSEASTLSTTPVDTSTPVTTS--TEASS 727
Query: 1622 KSPQPDPVKTPTSSKQRLKISLGKVGVKEEVLPVGKLT--QTSGKTTQTHRETAGDGKSI 1679
D PTS+ L + V + +L + + T+ T TH T+ +
Sbjct: 728 SPTTADGASMPTSTPSEGSTPLTSMPVSKTLLTSSEASTLSTTPLDTSTHITTSTEASCS 787
Query: 1680 KAFKESAKQMLDPANYGTGMERWPRTPKEEAQSLEDLAGFKELFQTPDHTEESTTD---- 1735
E + TP E + L + +P+ + STT
Sbjct: 788 PTTTEGTSMPIS-------------TPSEGSPLLTSIPVSITPVTSPEASTLSTTPVDSN 834
Query: 1736 ---DKTTKIACKSPPPESMDTPTSTRRRPKTPLGKRDIVEELSALKQLTQTTHTDKVPGD 1792
+T+++ P E PTST +TPL + L A ++ + T P D
Sbjct: 835 SPVTTSTEVSSSPTPAEGTSMPTSTYSEGRTPLTSMPVSTTLVATSAISTLSTT---PVD 891
Query: 1793 EDKGINVFRETAKQKLDPAASVTGSKRQPRTPKGKAQPLEDL---------AGLKELFQT 1843
+ + + + P S G+ TP + PL + + + L T
Sbjct: 892 TSTPVT---NSTEARSSPTTS-EGTSMPTSTPGEGSTPLTSMPDSTTPVVSSEARTLSAT 947
Query: 1844 PICTDKPTTHEKTTKIACRSPQP-DPVGTPTIFKPQSKRSLRKADVEEESLALRKRTPSV 1902
P+ T P T T+ A SP + PT + L V +A + +
Sbjct: 948 PVDTSTPVT---TSTEATSSPTTAEGTSIPTSTPSEGTTPLTSTPVSHTLVANSEASTLS 1004
Query: 1903 GKAMDTPKPAGGDEKDMKAFMGTPVQK-LDLPGNLPGSKRWPQTPKEKAQALEDLAGFKE 1961
+D+ P +A P + +P + P P T + + +
Sbjct: 1005 TTPVDSNTPL---TTSTEASSPPPTAEGTSMPTSTPSEGSTPLTRMPVSTTMVASSETST 1061
Query: 1962 LFQTPGTDKPTTDEKTTKIACKSPQPDPVDTPASTKQRPKRNLRKADVEEEFLALRKRTP 2021
L TP D T ++ + S D P ST L V + + +
Sbjct: 1062 LSTTPA-DTSTPVTTYSQASSSSTTADGTSMPTSTYSEGSTPLTSVPVSTRLVVSSEAST 1120
Query: 2022 SAGKAMDTPKPAVSDEKNINTFVETPVQKLDLLGNLPGSKRQPQTPKEKAEALEDLVGFK 2081
+ +DT P + + ++ T + + + P P + L
Sbjct: 1121 LSTTPVDTSIPVTTSTEASSS--PTTAEGTSIPTSPPSEGTTPLASMPVSTTLVVSSEAN 1178
Query: 2082 ELFQTPGHTEESMTDDKITEVSCKSPQPESFKTSRSSKQRLKIPLVKVDMKEEPLAVSKL 2141
L TP ++ + TE S P E S+ PL + ++ P+A S+
Sbjct: 1179 TLSTTPVDSKTQVATS--TEASSPPPTAEVTSMPTSTPGERSTPLTSMPVRHTPVASSEA 1236
Query: 2142 TRTSGETTQTHTEPTGDSKSIKAFKESPKQILDPAASVTGSRRQLRTRKEKARALEDLVD 2201
+ S T T T +++ + + L + + GS L T + L +
Sbjct: 1237 STLSTSPVDTSTPVTTSAETSSSPTTAEGTSLPTSTTSEGST--LLTSIPVSTTLVTSPE 1294
Query: 2202 FKELFSAPGHTEESMTIDKNTKIPCKSPPPELTDTATSTK---RCPKTR-PRKEVKEELS 2257
L + P T+ + + ++ P E T TST R P T P S
Sbjct: 1295 ASTLLTTPVDTKGPVVT--SNEVSSSPTPAEGTSMPTSTYSEGRTPLTSIPVNTTLVASS 1352
Query: 2258 AVERLTQTSGQ-------STHTHKEPASGDEGIKVLKQRAKKKPNPVEEEPSRRRPRAPK 2310
A+ L+ T ST P + EG + + P+ P P
Sbjct: 1353 AISILSTTPVDNSTPVTTSTEACSSPTTS-EGTSMPNSNPSEGTTPLTSIPVSTTPVVSS 1411
Query: 2311 EKAQPLEDLAGFTELSETSGHTQE-SLTAGKATKIPCESPPLEVVDTTASTKRHLRTRVQ 2369
E + LS T T T+ +AT P + E + ST +T ++
Sbjct: 1412 EAST----------LSATPVDTSTPGTTSAEATSSPTTA---EGISIPTSTPSEGKTPLK 1458
Query: 2370 KVQVKEEPSAVKFTQTSGETTDADKEPAGEDKGIKALKESAKQTPAPAASVTGSRRRPRA 2429
+ V P A T T P + + S+ TPA S+ S
Sbjct: 1459 SIPVSNTPVANSEASTLSTTPVDSNSPV-----VTSTAVSSSPTPAEGTSIAIS-----T 1508
Query: 2430 PRESAQAIEDLAGFKDPAAGHTEESMTDDKTTKIPCKSSPELEDTATSSKRRPRTRAQKV 2489
P E + A+ T IP ++ S P + V
Sbjct: 1509 PSEGSTAL-----------------------TSIPVSTTTVASSEINSLSTTPAVTSTPV 1545
Query: 2490 EVKEELLAVGKLTQTSGETTHTDKEPVGEGKGTKAFKQPAKRKLDAEDVIGSRRQPRAPK 2549
+ + + T+ + T EG T P L V+ S A
Sbjct: 1546 TTYSQASS----SPTTADGTSMQTSTYSEGS-TPLTSLPVSTML----VVSSE----ANT 1592
Query: 2550 EKAQPLEDLASFQELSQTPGHTEELANGAADSFTSAPKQTPDSGKPLKISRRVLRAPKVE 2609
P++ +Q TE ++ A+ +S TP G PL S V P
Sbjct: 1593 LSTTPIDSK------TQVTASTEASSSTTAEG-SSMTISTPSEGSPLLTSIPVSTTPVAS 1645
Query: 2610 PVGDVVSTRDPVKSQSKSNTS 2630
P +ST PV S S TS
Sbjct: 1646 PEASTLST-TPVDSNSPVITS 1665
Score = 77.4 bits (189), Expect = 2e-13
Identities = 427/2238 (19%), Positives = 690/2238 (30%), Gaps = 291/2238 (13%)
Query: 481 VAKTPRNTYKMTSLETKTSDTETEPSKT-VSTANRSGRSTEFRNIQKLPVESKSEETNTE 539
+A P +T + S E T T SKT V+T+ + + +P + E + T
Sbjct: 1162 LASMPVSTTLVVSSEANTLSTTPVDSKTQVATSTEASSPPPTAEVTSMPTSTPGERS-TP 1220
Query: 540 IVECILKRGQKATLLQQRREGEMKEIERPFETYKENIELKENDEKMKAMKRSRTWGQKCA 599
+ ++ A+ + P T E E + + G
Sbjct: 1221 LTSMPVRHTPVASSEASTLSTSPVDTSTPVTTSAETSSSPTTAEGTSLPTSTTSEGS--- 1277
Query: 600 PMSDLTDLKSLPDTELMKDTARGQNLLQTQDHAKAPKSEKGKITKMPCQSLQPEPINTPT 659
T L S+P + + + LL T K P +++ P + E + PT
Sbjct: 1278 -----TLLTSIPVSTTLVTSPEASTLLTTPVDTKGPVVTSNEVSSSPTPA---EGTSMPT 1329
Query: 660 HTKQQLKASLGKVGVKEELLAVGKF-----TRTSGETTHTHREPAGDGKSIRTFKESPKQ 714
T + + L + V L+A T T T A + P
Sbjct: 1330 STYSEGRTPLTSIPVNTTLVASSAISILSTTPVDNSTPVTTSTEACSSPTTSEGTSMPNS 1389
Query: 715 ILDPAARVTGMKKWP--RTPKEEAQSLEDLAGFKELFQTPGPSEESMTDEKTTKIACKSP 772
+P+ T + P TP +++ L+ TPG + T TT P
Sbjct: 1390 --NPSEGTTPLTSIPVSTTPVVSSEA-STLSATPVDTSTPGTTSAEATSSPTTAEGISIP 1446
Query: 773 PPESVDTPTSTKQWPKRSLRKADVEEEFLALRKLTPSAGKAMLT-----PKPAGGDEKDI 827
+ T K P + A+ E L+ + ++ T P PA G I
Sbjct: 1447 TSTPSEGKTPLKSIPVSNTPVANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIAI 1506
Query: 828 KAFMGTPVQKLDLAGTLPGSKRQLQTPKEKAQALEDLAGFKELFQTPGHTEELVAAGKTT 887
TP + ++P S T + + L+ + TP T ++ TT
Sbjct: 1507 S----TPSEGSTALTSIPVS-----TTTVASSEINSLSTTPAVTSTPVTTYSQASSSPTT 1557
Query: 888 KIPCDSPQSDPVDTPTSTKQRPKRSIRKADVEGELLACRNLMPSAGKAMHTPKPSVGEEK 947
S + T P ++ E L+ + T S +
Sbjct: 1558 ADGTSMQTSTYSEGSTPLTSLPVSTMLVVSSEANTLSTTPIDSKTQVTASTEASSSTTAE 1617
Query: 948 DIIIFVGTPVQKLDLTENLTGSKRRPQTPKEEAQALEDLTGFKELFQTPGHTEEAVAAGK 1007
+ + TP + L ++ S +P+ L TP + V
Sbjct: 1618 GSSMTISTPSEGSPLLTSIPVSTTPVASPEAST-----------LSTTPVDSNSPVIT-- 1664
Query: 1008 TTKMPCESSPPESADTPTSTRRQPKTPLEKRDVQKELSALKKLTQTSGETTHTDKVPGGE 1067
+T++ +P E PTST + +TPL V+ A ++ S TT D
Sbjct: 1665 STEVSSSPTPAEGTSMPTSTYTEGRTPLTSITVRTTPVASSAISTLS--TTPVD------ 1716
Query: 1068 DKSINAFRETAKQKLDPAASVTGSKRHPKTKEKAQPLEDL---------AGLKELFQTPV 1118
+ + + + P S S + E PL + + L TP+
Sbjct: 1717 --NSTPVTTSTEARSSPTTSEGTSMPNSTPSEGTTPLTSIPVSTTPVLSSEASTLSATPI 1774
Query: 1119 CTDKPTTHEKTTKIACRSQPDPVDTPTSSKPQSKRSLRKVDVEEEFFALRKRTPSAGKAM 1178
T P T T + + + PTS+ + L V A + + + +
Sbjct: 1775 DTSTPVT-TSTEATSSPTTAEGTSIPTSTLSEGMTPLTSTPVSHTLVANSEASTLSTTPV 1833
Query: 1179 HTPKPAVSGEKNIYAFMGTPVQKLDLTENLTGSKRRLQTPKEKAQALEDLAGFKELFQTR 1238
+ P V+ + TP + G+ TP E + AL + +
Sbjct: 1834 DSNSPVVTS--TAVSSSPTPAE---------GTSIATSTPSEGSTALTSIPVSTTTVASS 1882
Query: 1239 G----HTEESMTNDKTAKVACKSSQP---DPDKNPASSKRRLKTSLGKVGVKEELLAVGK 1291
T ++T+ A SS P D P S+ R + L + V +A +
Sbjct: 1883 ETNTLSTTPAVTSTPVTTYAQVSSSPTTADGSSMPTSTPREGRPPLTSIPVSTTTVASSE 1942
Query: 1292 LTQTSGETTHTHTEPTGDGKSMKAFMESPKQILDSAASLTGSKRQLRTPKGKSEVPEDLA 1351
+ S T T T ++ S++ T + TP
Sbjct: 1943 INTLSTTLADTRTPVTTYSQA-------------SSSPTTADGTSMPTPAYSE------- 1982
Query: 1352 GFIELFQTPSHTKESMTNEKTT--KVSYRASQPDLVDTPTSSKPQPK--RSLRKADTEEE 1407
G L P T +++E +T S P T SS P S++ + E
Sbjct: 1983 GSTPLTSMPLSTTLVVSSEASTLSTTPVDTSTPATTSTEGSSSPTTAGGTSIQTSTPSE- 2041
Query: 1408 FLAFRKQTPSAGKAMHTPKPAVGEEKDINTFLGTPVQKLDQPGNLPGSNRRLQTRKEKAQ 1467
+ TP AG + T E ++T TPV Q N ++
Sbjct: 2042 -----RTTPLAGMPVSTTLVVSSEGNTLST---TPVDSKTQVTNSTEASSSATAEGSSMT 2093
Query: 1468 ALEELTGFRELFQTPCTDNPTTDEKTTKKILCKSPQSDPADTPTNTKQRPKRSLKKADVE 1527
G L P + P + + + P T T P + + ++
Sbjct: 2094 ISAPSEGSPLLTSIPLSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSPIPT-EGTSMQ 2152
Query: 1528 EEFLAFRKLTPSAGKAMHTPKAAVGEEKDINTFVGTPVEKLDLLGNLPGSKRRPQTPKEK 1587
+ R+ TP + T A I+T TPV+ + N ++ P T +
Sbjct: 2153 TSTYSDRR-TPLTSMPVSTTVVA---SSAISTLSTTPVDTSTPVTNSTEARSSPTTSE-- 2206
Query: 1588 AKALEDLAGFKELFQTPGHTEESMTDDKITEVSCKSPQPDPVKTPTSSKQRLKISLGKVG 1647
G TP T ++ + PV T +S
Sbjct: 2207 --------GTSMPTSTPSEGSTPFTSMPVSTM--------PVVTSEASTL---------- 2240
Query: 1648 VKEEVLPVGKLTQTSGKTTQTHRETAGDGKSIKAFKESAKQMLDPANYGTGMERWPRTPK 1707
PV T + T T T +G SI S GT TP
Sbjct: 2241 ---SATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTLSE---------GT-------TPL 2281
Query: 1708 EEAQSLEDLAGFKELFQTPDHTEESTTDDKTTKIACKSPPP--ESMDTPTSTRRRPKTPL 1765
L E+ T T + TT SPPP E PTST TPL
Sbjct: 2282 TSIPVSHTLVANSEV-STLSTTPVDSNTPFTTSTEASSPPPTAEGTSMPTSTSSEGNTPL 2340
Query: 1766 GKRDIVEELSALKQLTQTTHTDKVPGDEDKGINVFRE--TAKQKLDPAASVTGSKRQPRT 1823
+ + + A +T+ P D + + + ++ D + T + + T
Sbjct: 2341 TRMPVSTTMVA---SFETSTLSTTPADTSTPVTTYSQAGSSPTTADDTSMPTSTYSEGST 2397
Query: 1824 PKGKAQPLEDLAGLKELFQTPICTDKPTTHEKTTKIACRSPQPDPVGTPTIFKPQSKRSL 1883
P + P+ + + T T T+ TT S GT P S+ +
Sbjct: 2398 PL-TSVPVSTMPVVSSEASTHSTTPVDTSTPVTTSTEASSSPTTAEGTSIPTSPPSEGTT 2456
Query: 1884 RKAD--------VEEESLALRKRTPSVGKAMDTPKPAGGD---EKDMKAFMGTPVQKLDL 1932
A V E+ L M T A +D+ + T + L
Sbjct: 2457 PLASMPVSTTPVVSSEAGTLSTTPVDTSTPMTTSTEASSSPTTAEDIVVPISTASEGSTL 2516
Query: 1933 PGNLPGSKRWPQTPKEKAQALEDLAGFKELFQTPGTDKPTTDEKTTKIACKSPQPDPVDT 1992
++P S TP +A T D + +T+I+ + +
Sbjct: 2517 LTSIPVS----TTPVASPEA--------STLSTTPVDSNSPVVTSTEISSSATSAEGTSM 2564
Query: 1993 PASTKQRPKRNLRKADVEEEFLALRKRTPSAGKAMDTPKPAVSDEKNINTFVETPVQKLD 2052
P ST LR V + LA + + + +DT P + + + +P D
Sbjct: 2565 PTSTYSEGSTPLRSMPVSTKPLASSEASTLSTTPVDTSIPVTTSTETSS----SPTTAKD 2620
Query: 2053 LLGNLPGSKRQPQTPKEKAEALEDLV---------GFKELFQTPGHTEESMTDDKITEVS 2103
++P S TP E + +L ++ L TP T +T T S
Sbjct: 2621 T--SMPIS-----TPSEVSTSLTSILVSTMPVASSEASTLSTTPVDTRTLVTTSTGTSSS 2673
Query: 2104 CKSPQPESFKTSRSSKQRLKIPLVKVD-----------MKEEPLAVSKLTRTSGETTQTH 2152
+ + S TS ++ + + V + P+ S TS E + +
Sbjct: 2674 PTTAEGSSMPTSTPGERSTPLTNILVSTTLLANSEASTLSTTPVDTSTPVTTSAEASSSP 2733
Query: 2153 TEPTGDSKSIKAFKESPKQILDPAASVTGSRRQLRTRKEKARALEDLVDFKELFSAPGHT 2212
T G S I +P P S+ S + + E + VD +
Sbjct: 2734 TTAEGTSMRI----STPSDGSTPLTSILVSTLPVAS-SEASTVSTTAVDTSIPVTTSTEA 2788
Query: 2213 EESMTIDKNTKIPCKSPPPELTDTATSTKRCPKTRPRKEVKEELSAVERLTQTSGQSTHT 2272
S T + T +P +P ++T+T P E + TS T +
Sbjct: 2789 SSSPTTAEVTSMPTSTP----SETSTPLTSMPVNHTPVASSEAGTLSTTPVDTSTPVTTS 2844
Query: 2273 HKEPASGD--EGIKVLKQRAKKKPNPVEEEPSRRRPRAPKEKAQPLEDLAGFTELS-ETS 2329
K +S EGI V A + + P P A E A L T + TS
Sbjct: 2845 TKASSSPTTAEGIVVPISTASEGSTLLTSIPVSTTPVASSE-ASTLSTTPVDTSIPVTTS 2903
Query: 2330 GHTQESLTAGKATKIPCESPPLEVVDTTASTKRHLRTRVQKVQVKEEPSAVKFTQTSGET 2389
S T + T +P ST + T + + V P A T T
Sbjct: 2904 TEGSSSPTTAEGTSMP------------ISTPSEVSTPLTSILVSTVPVAGSEASTLSTT 2951
Query: 2390 TDADKEPAGEDKGIKALKESAKQTPAPAASVTGSRRRPRAPRESAQAIEDLAGFKDPAAG 2449
+ P + +A+ T P S G RR P + + +A +
Sbjct: 2952 PVDTRTPVTTSAEASSSPTTAEGTSMP-ISTPGERRTPLT--SMSVSTMPVASSEASTLS 3008
Query: 2450 HTEESMTDDKTTKIPCKSSP---ELEDTATSSKRRPRTRAQKVEVKEELLAVGKLTQTSG 2506
T + TT SSP E S+ T + V +A+ + + S
Sbjct: 3009 RTPADTSTPVTTSTEASSSPTTAEGTGIPISTPSEGSTPLTSIPVSTTPVAIPEASTLS- 3067
Query: 2507 ETTHTD-KEPVGEGKGTKAFKQPAKRKLDAEDVIGSRRQPRAPKEKAQPLEDLASFQELS 2565
TT D PV + PA+ P + ++ LS
Sbjct: 3068 -TTPVDSNSPVVTSTEVSSSPTPAEGTSMPISTYSEGSTPLTGVPVSTTPVTSSAISTLS 3126
Query: 2566 QTP--------GHTEELANGAADSFTSAPKQTPDSGK-PLKISRRVLRAPKVEPVGD--V 2614
TP TE ++ TS P TP G PL PV V
Sbjct: 3127 TTPVDTSTPVTTSTEAHSSPTTSEGTSMPTSTPSEGSTPLTYM----------PVSTMLV 3176
Query: 2615 VSTRDPVKSQSKSNTSLP 2632
VS+ D S + +TS P
Sbjct: 3177 VSSEDSTLSATPVDTSTP 3194
Score = 75.9 bits (185), Expect = 6e-13
Identities = 448/2370 (18%), Positives = 710/2370 (29%), Gaps = 310/2370 (13%)
Query: 433 SGEEPLLPTSESFGGNVFFSAQNAAKQPSDKCSASP----PLRRQCIRENGNVAKTPRNT 488
+ E +PTS G+ ++ A+ P S P+ + + T
Sbjct: 318 TAEGTSIPTSTYTEGSTPLTSTPASTMPVATSEMSTLSITPVDTSTLVTTSTEPSSLPTT 377
Query: 489 YKMTSLETKTSDTETEPSKTVSTANRSGRSTEFRNIQKLPVESKSEETNTEIVECILKRG 548
+ TS+ T T + P + + S+E +PV+SK+ T
Sbjct: 378 AEATSMLTSTLSEGSTPLTNMPVSTILVASSEASTTSTIPVDSKTFVTTASEASSSPTTA 437
Query: 549 QKATLLQQR-REGEMKEIERPFET----YKENIELKENDEKMKAMKRSRTWGQKCAPMSD 603
+ ++ EG P T E L K + T P ++
Sbjct: 438 EDTSIATSTPSEGSTPLTSMPVSTTPVASSEASNLSTTPVDSKTQVTTSTEASSSPPTAE 497
Query: 604 L------------TDLKSLPDTELMKDTARGQNLLQTQDHAKAPKSEKGKITKMPCQSLQ 651
+ T L S+ + + ++ L T P + + + S
Sbjct: 498 VNSMPTSTPSEGSTPLTSMSVSTMPVASSEASTLSTTPVDTSTPVTTSSEASS---SSTT 554
Query: 652 PEPINTPTHTKQQLKASLGKVGVKEELLAVGK-------------FTRTSGETTHTHREP 698
PE + PT T + L + V L+ + F TS E + +
Sbjct: 555 PEGTSIPTSTPSEGSTPLTNMPVSTRLVVSSEASTTSTTPADSNTFVTTSSEASSSSTTA 614
Query: 699 AGDGKSIRTFKESPKQILDPAARVTGM--------------KKWPRTPKEEAQSLEDLA- 743
G T+ E I + T + P T EA S A
Sbjct: 615 EGTSMPTSTYSERGTTITSMSVSTTLVASSEASTLSTTPVDSNTPVTTSTEATSSSTTAE 674
Query: 744 --GFKELFQTPGPSEESMTDEKTTKIACK-----SPPPESVDTPTSTKQWPKRSLRKADV 796
T G + + TT +A S P TP +T S AD
Sbjct: 675 GTSMPTSTYTEGSTPLTSMPVNTTLVASSEASTLSTTPVDTSTPVTTSTEASSSPTTAD- 733
Query: 797 EEEFLALRKLTPSAGKAMLTPKPAGGDEKDIKAFMGTPVQKLDLAGTLPGSKRQLQTPKE 856
++ TPS G LT P + + T + L+ T + + T E
Sbjct: 734 ---GASMPTSTPSEGSTPLTSMP-------VSKTLLTSSEASTLSTTPLDTSTHITTSTE 783
Query: 857 KAQALEDLAGFKELFQTPGHTEELVAAGKTTKIPCDSPQSD-----PVDTPTSTKQRPKR 911
+ + G TP L+ + + P SP++ PVD+ + +
Sbjct: 784 ASCSPTTTEGTSMPISTPSEGSPLLTSIPVSITPVTSPEASTLSTTPVDSNSPVTTSTEV 843
Query: 912 SIRKADVEGELLACRNLMPSAGKAMHTPKP---SVGEEKDIIIFVGTPVQKLDLTENLTG 968
S EG + S G+ T P ++ I TPV N T
Sbjct: 844 SSSPTPAEGTSMPTSTY--SEGRTPLTSMPVSTTLVATSAISTLSTTPVDTSTPVTNSTE 901
Query: 969 SKRRP----------QTPKEEAQALEDL---------TGFKELFQTPGHTEEAVAAGKTT 1009
++ P TP E + L + + + L TP T V TT
Sbjct: 902 ARSSPTTSEGTSMPTSTPGEGSTPLTSMPDSTTPVVSSEARTLSATPVDTSTPV----TT 957
Query: 1010 KMPCESSP--PESADTPTSTRRQPKTPLEKRDVQKELSALKKLTQTSGETTHTDKVPGGE 1067
SSP E PTST + TPL V L A + + S TT D
Sbjct: 958 STEATSSPTTAEGTSIPTSTPSEGTTPLTSTPVSHTLVANSEASTLS--TTPVDS----- 1010
Query: 1068 DKSINAFRETAKQKLDPAASVTGSKRHPKT-KEKAQPLEDL---------AGLKELFQTP 1117
N T+ + P + G+ T E + PL + + L TP
Sbjct: 1011 ----NTPLTTSTEASSPPPTAEGTSMPTSTPSEGSTPLTRMPVSTTMVASSETSTLSTTP 1066
Query: 1118 VCTDKP-TTHEKTTKIACRSQPDPVDTPTSSKPQSKRSLRKVDVEEEFFALRKRTPSAGK 1176
T P TT+ + + + + D PTS+ + L V V + + +
Sbjct: 1067 ADTSTPVTTYSQAS--SSSTTADGTSMPTSTYSEGSTPLTSVPVSTRLVVSSEASTLSTT 1124
Query: 1177 AMHTPKPAVSGEKNIYAFMGTPVQKLDLTENLTGSKRRLQTPKEKAQALEDLAGFKEL-F 1235
+ T P T + G+ P E L + L
Sbjct: 1125 PVDTSIPVT-----------TSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTLVV 1173
Query: 1236 QTRGHTEESMTNDKTAKVA--CKSSQPDPDKN----PASSKRRLKTSLGKVGVKEELLAV 1289
+ +T + D +VA ++S P P P S+ T L + V+ +A
Sbjct: 1174 SSEANTLSTTPVDSKTQVATSTEASSPPPTAEVTSMPTSTPGERSTPLTSMPVRHTPVAS 1233
Query: 1290 GKLTQTSGETTHTHTEPTGDGKSMKAFMESPKQILDSAASLTGSKRQLRTPKGKSEVPED 1349
+ + S T T T ++ + + L ++ + GS P + V
Sbjct: 1234 SEASTLSTSPVDTSTPVTTSAETSSSPTTAEGTSLPTSTTSEGSTLLTSIPVSTTLVTSP 1293
Query: 1350 LAGFIELFQTPSHTKESMTNEKTTKVSYRASQPDLVDTPTSSKPQPKRSLRKADTEEEFL 1409
A L TP TK + + +VS + + PTS+ + + L +
Sbjct: 1294 EAS--TLLTTPVDTKGPVVT--SNEVSSSPTPAEGTSMPTSTYSEGRTPLTSIPVNTTLV 1349
Query: 1410 AFRKQTPSAGKAMHTPKPAVGEEKDIN---TFLGTPVQKLD-QPGNLPGSNRRLQTRKEK 1465
A + + + P + + T GT + + G P ++ + T
Sbjct: 1350 ASSAISILSTTPVDNSTPVTTSTEACSSPTTSEGTSMPNSNPSEGTTPLTSIPVSTTPVV 1409
Query: 1466 AQALEELTGFRELFQTPCTDNPTTDEKTTKKILCKSPQSDPADTPTNTKQRPKRSLKKAD 1525
+ L+ TP T + T P S P++ T K P + A+
Sbjct: 1410 SSEASTLSATPVDTSTPGTTSAEATSSPTTAEGISIPTSTPSEGKTPLKSIPVSNTPVAN 1469
Query: 1526 VEEEFLAFRKLTPSAGKAMHTPKAAVGEEKDINTFVGTPVEKLDLLGNLPGSKRRPQTPK 1585
E L+ TP + AV TP E + + P T
Sbjct: 1470 SEASTLS---TTPVDSNSPVVTSTAVSSSP-------TPAEGTSIAISTPSEGSTALTSI 1519
Query: 1586 EKAKALEDLAGFKELFQTPGHTEESMTDDKITEVSCKSPQPDPVKTPTSSKQRLKISLGK 1645
+ + L TP T +T + P +S Q S G
Sbjct: 1520 PVSTTTVASSEINSLSTTPAVTSTPVT-------TYSQASSSPTTADGTSMQTSTYSEGS 1572
Query: 1646 VGVKEEVLPVGKLTQTSGKTTQTHRETAGDGKSIKAFKESAKQMLDPANYGTGMERWPRT 1705
+ LPV + S + T T D K+ + +A + G T
Sbjct: 1573 TPLTS--LPVSTMLVVSSE-ANTLSTTPIDSKT----QVTASTEASSSTTAEGSSMTIST 1625
Query: 1706 PKEEAQSLEDLAGFKELFQTPDHTEESTTD-------DKTTKIACKSPPPESMDTPTSTR 1758
P E + L + +P+ + STT +T+++ P E PTST
Sbjct: 1626 PSEGSPLLTSIPVSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSPTPAEGTSMPTSTY 1685
Query: 1759 RRPKTPLGKRDIVEELSALKQLTQTTHTDKVPGDEDKGINVFRETAKQKLDPAASVTGSK 1818
+TPL T+ T + I+ T P + T ++
Sbjct: 1686 TEGRTPL-----------------TSITVRTTPVASSAISTLSTTPVDNSTPVTTSTEAR 1728
Query: 1819 RQPRTPKGKAQPLEDLA-GLKELFQTPICTDKPTTHEKTTKIACRSPQPDPVGTPTIFKP 1877
P T +G + P + G L P+ T + E +T A PV T T
Sbjct: 1729 SSPTTSEGTSMPNSTPSEGTTPLTSIPVSTTPVLSSEASTLSATPIDTSTPVTTST---- 1784
Query: 1878 QSKRSLRKADVEEESLALRKRTPSVGKAMDTPKPAGGD---EKDMKAFMGTPVQK----- 1929
+ E ++ T S G T P + TPV
Sbjct: 1785 ----EATSSPTTAEGTSIPTSTLSEGMTPLTSTPVSHTLVANSEASTLSTTPVDSNSPVV 1840
Query: 1930 -----LDLPGNLPGSKRWPQTPKEKAQALEDL-----AGFKELFQTPGTDKPTTDEKTTK 1979
P G+ TP E + AL + T T T T
Sbjct: 1841 TSTAVSSSPTPAEGTSIATSTPSEGSTALTSIPVSTTTVASSETNTLSTTPAVTSTPVTT 1900
Query: 1980 IACKSPQPDPVD---TPASTKQRPKRNLRKADVEEEFLALRKRTPSAGKAMDTPKPAVSD 2036
A S P D P ST + + L V +A + + DT P +
Sbjct: 1901 YAQVSSSPTTADGSSMPTSTPREGRPPLTSIPVSTTTVASSEINTLSTTLADTRTPVTTY 1960
Query: 2037 EKNINTFVETPVQKLDLLGNLPGSKRQPQTPKEKAEALEDLVGFKELFQTPGHTEESMTD 2096
+ ++ + GS P T + L L TP T T
Sbjct: 1961 SQASSSPTTADGTSMPTPAYSEGS--TPLTSMPLSTTLVVSSEASTLSTTPVDTSTPATT 2018
Query: 2097 DKITEVSCKSPQPESFKTSRSSKQRLKIPLVKVDMKEEPLAVSKLTRTSGETTQTHTEPT 2156
S + S +TS S++ PL + P++ + + + G T T P
Sbjct: 2019 STEGSSSPTTAGGTSIQTSTPSER--TTPLAGM-----PVSTTLVVSSEGNTLS--TTPV 2069
Query: 2157 GDSKSIKAFKESPKQILDPAASVTGSRRQLRTRKEKARALEDL-VDFKELFSAPGHTEES 2215
+ E+ +A+ GS + E + L + + + S T +
Sbjct: 2070 DSKTQVTNSTEA-----SSSATAEGSSMTISAPSEGSPLLTSIPLSTTPVASPEASTLST 2124
Query: 2216 MTIDKN------TKIPCKSPPPELTDTATST---KRCPKT-RPRKEVKEELSAVERLTQT 2265
+D N T++ P E T TST +R P T P SA+ L+ T
Sbjct: 2125 TPVDSNSPVITSTEVSSSPIPTEGTSMQTSTYSDRRTPLTSMPVSTTVVASSAISTLSTT 2184
Query: 2266 S-------GQSTHTHKEPASGDEGIKVLKQRAKKKPNPVEEEPSRRRPRAPKE----KAQ 2314
ST P + EG + + P P P E A
Sbjct: 2185 PVDTSTPVTNSTEARSSPTT-SEGTSMPTSTPSEGSTPFTSMPVSTMPVVTSEASTLSAT 2243
Query: 2315 PLEDLAGFTELSETSGHTQESLTAGKATKIPCESPPLEVVDTTASTKRHLRTRVQKVQVK 2374
P++ T TS S T + T IP + T+ H +V
Sbjct: 2244 PVDTSTPVT----TSTEATSSPTTAEGTSIPTSTLSEGTTPLTSIPVSHTLVANSEVSTL 2299
Query: 2375 EEPSAVKFTQTSGETTDADKEPAGEDKGIKALKESAKQTPAP---------AASVTGSRR 2425
T + T + P E + S TP A+ T +
Sbjct: 2300 STTPVDSNTPFTTSTEASSPPPTAEGTSMPTSTSSEGNTPLTRMPVSTTMVASFETSTLS 2359
Query: 2426 RPRAPRESAQAIEDLAGFKDPAAGHTE---ESMTDDKT--TKIPCKSSPELEDTATSSKR 2480
A + AG A T + ++ T T +P + P + A++
Sbjct: 2360 TTPADTSTPVTTYSQAGSSPTTADDTSMPTSTYSEGSTPLTSVPVSTMPVVSSEASTHST 2419
Query: 2481 RPRTRAQKVEVKEELLAVGKLTQTSGETTHTDKEPVGEGKGTKAFKQPAKRKLDAEDVIG 2540
P + V E + T+ E T P EG T P G
Sbjct: 2420 TPVDTSTPVTTSTE----ASSSPTTAEGTSIPTSPPSEGT-TPLASMPVSTTPVVSSEAG 2474
Query: 2541 SRRQPRAPKEKAQPLEDLASFQELSQTPGHTEELANGAADSFTSAPKQTPDSGKPLKISR 2600
+ P + + P + + E S +P E++ P T G L S
Sbjct: 2475 T--LSTTPVDTSTP---MTTSTEASSSPTTAEDIV---------VPISTASEGSTLLTSI 2520
Query: 2601 RVLRAPKVEPVGDVVSTRDPVKSQSKSNTS 2630
V P P +ST PV S S TS
Sbjct: 2521 PVSTTPVASPEASTLST-TPVDSNSPVVTS 2549
Score = 75.1 bits (183), Expect = 9e-13
Identities = 361/1905 (18%), Positives = 589/1905 (30%), Gaps = 286/1905 (15%)
Query: 900 DTP--TSTKQRPKRSIRKADVEGELLACRNLMPSAGKAMHTPKPSVGEEKDIIIFVGTPV 957
DTP +ST+ P S ++ + L PS+ + T P+ E D+ + TP
Sbjct: 101 DTPGVSSTRMTPTESRTTSESTSD---STTLFPSSTE--DTSSPTTPEGTDVPM--STPS 153
Query: 958 QKLDLTENLTGSKRRPQT-PKEEAQALEDLTGFKELFQTPGHTEEAVAAGKTTKMPCESS 1016
+ E+++ + T P +A LT +K TP T ++ TT
Sbjct: 154 E-----ESISSTMAFVSTAPLPSFEAYTSLT-YKVDMSTPLTTSTQASSSPTT------- 200
Query: 1017 PPESADTPTSTRRQPKTPLEKRDVQKELSALKKLTQTSGETTHTDKVPGGEDKSINAFRE 1076
PES P ST + TPL ++ K+ + T T V +I+A
Sbjct: 201 -PESTTIPKSTNSEGSTPLTSMP-----ASTMKVASSEAITLLTTPVEISTPVTISAQAS 254
Query: 1077 TAKQKLDPAASVTGSKRHPKTKEKAQPLEDL----AGLKELFQTPVCTD----------- 1121
++ + + + T PL + + L TP T+
Sbjct: 255 SSPTTAEGPSLSNSAPSGGSTPLTRMPLSVMLVVSSEASTLSTTPAATNIPVITSTEASS 314
Query: 1122 KPTTHEKT---TKIACRSQPDPVDTPTSSKPQSKRSLRKVDVEEEFFALRKRTPSAGKAM 1178
PTT E T T TP S+ P + + + + + T + ++
Sbjct: 315 SPTTAEGTSIPTSTYTEGSTPLTSTPASTMPVATSEMSTLSITPVDTSTLVTTSTEPSSL 374
Query: 1179 HTPKPAVSGEKNIYAFMGTPVQKLDLTENLTGSKRRLQTPKEKAQALEDLAGFKELFQTR 1238
T A S + + TP+ + ++ L S T + K T
Sbjct: 375 PTTAEATSMLTSTLSEGSTPLTNMPVSTILVASSEASTTSTIPVDS-------KTFVTTA 427
Query: 1239 GHTEESMTNDKTAKVACKSSQPDPDKNPASSKRRLKTSLGKVGVKE-ELLAVGKLTQTSG 1297
S T + +A +S P P +S T + V TQ +
Sbjct: 428 SEASSSPTTAEDTSIA--TSTPSEGSTPLTSMPVSTTPVASSEASNLSTTPVDSKTQVTT 485
Query: 1298 ETTHTHTEPTGDGKSMKAFMESPKQILDSAASLTGSKRQLRTPKGKSEVPEDLAGFIELF 1357
T + + PT + SM S + + LT S P SE L
Sbjct: 486 STEASSSPPTAEVNSMPTSTPS-----EGSTPLT-SMSVSTMPVASSEAS-------TLS 532
Query: 1358 QTPSHTKESMTNEKTTKVSYRASQPDLVDTPTSSKPQPKRSLRKADTEEEFLAFRKQTPS 1417
TP T +T +++ S ++ P+ PTS+ + L + +
Sbjct: 533 TTPVDTSTPVTT--SSEASSSSTTPEGTSIPTSTPSEGSTPLTNMPVSTRLVV----SSE 586
Query: 1418 AGKAMHTPKPAVGEEKDINTFLGTPVQKLDQPGNLPGSNRRLQTRKEKAQALEEL----- 1472
A TP D NTF+ T + G++ T E+ + +
Sbjct: 587 ASTTSTTP-------ADSNTFVTTSSEASSSSTTAEGTSMPTSTYSERGTTITSMSVSTT 639
Query: 1473 ----TGFRELFQTPCTDNPTTDEKTTKKILCKSPQSDPADTPTNTKQRPKRSLKKADVEE 1528
+ L TP N T T+ + S ++ PT+T L V
Sbjct: 640 LVASSEASTLSTTPVDSN--TPVTTSTEATSSSTTAEGTSMPTSTYTEGSTPLTSMPVNT 697
Query: 1529 EFLAFRKLTPSAGKAMHTPKAAVGEEKDINTFVGTPVEKLDLLGNLPGSKRRPQTPKEKA 1588
+A + A TP D +T V T E G+ TP E +
Sbjct: 698 TLVA----SSEASTLSTTP-------VDTSTPVTTSTEASSSPTTADGASMPTSTPSEGS 746
Query: 1589 KALEDLAGFKELF---------QTPGHTEESMTDDKITEVSCKSPQPD----PVKTPTSS 1635
L + K L TP T +T TE SC + P+ TP+
Sbjct: 747 TPLTSMPVSKTLLTSSEASTLSTTPLDTSTHITTS--TEASCSPTTTEGTSMPISTPSEG 804
Query: 1636 KQRL---KISLGKVGVKE----EVLPVGKLTQTSGKTTQTHRETAGDGKSIKAFKESAKQ 1688
L +S+ V E PV + + T + T +G S
Sbjct: 805 SPLLTSIPVSITPVTSPEASTLSTTPVDSNSPVTTSTEVSSSPTPAEGTS---------- 854
Query: 1689 MLDPANYGTGMERWPRTPKEEAQSLEDLAGFKELFQTPDHTEESTTDDKTTKIACKSPPP 1748
+ + Y G R P T + +L + L TP + ST +T+
Sbjct: 855 -MPTSTYSEG--RTPLTSMPVSTTLVATSAISTLSTTP--VDTSTPVTNSTEARSSPTTS 909
Query: 1749 ESMDTPTSTRRRPKTPLGKRDIVEELSALKQLTQTTHTDKVPGDEDKGINVFRETAKQKL 1808
E PTST TPL + T V E + ++ T
Sbjct: 910 EGTSMPTSTPGEGSTPL--------------TSMPDSTTPVVSSEARTLSA---TPVDTS 952
Query: 1809 DPAASVTGSKRQPRTPKGKAQPLEDLAGLKELFQTPICTDKPTTHEKTTKIACRSPQPDP 1868
P + T + P T +G + P TP+ T P +H + P
Sbjct: 953 TPVTTSTEATSSPTTAEGTSIP----TSTPSEGTTPL-TSTPVSHTLVANSEASTLSTTP 1007
Query: 1869 VGTPTIFKPQSKRSLRKADVEEESLALRKRTPSVGKAMDTPKPAGGDEKDMKAFMGTPVQ 1928
V + T ++ S E G +M T P+ G TP+
Sbjct: 1008 VDSNTPLTTSTEASSPPPTAE-------------GTSMPTSTPSEG---------STPLT 1045
Query: 1929 KLDLPGNLPGSKRWPQTPKEKAQALEDLAGFKELFQTPGTDKPTTDEKTTKIACKSPQPD 1988
++ + + S T D T ++ + S D
Sbjct: 1046 RMPVSTTMVASSE------------------TSTLSTTPADTSTPVTTYSQASSSSTTAD 1087
Query: 1989 PVDTPASTKQRPKRNLRKADVEEEFLALRKRTPSAGKAMDTPKPAVSDEKNINTFVETPV 2048
P ST L V + + + + +DT P + + ++ T
Sbjct: 1088 GTSMPTSTYSEGSTPLTSVPVSTRLVVSSEASTLSTTPVDTSIPVTTSTEASSS--PTTA 1145
Query: 2049 QKLDLLGNLPGSKRQPQTPKEKAEALEDLVGFKELFQTPGHTEESMTDDKITEVSCKSPQ 2108
+ + + P P + L L TP ++ + TE S P
Sbjct: 1146 EGTSIPTSPPSEGTTPLASMPVSTTLVVSSEANTLSTTPVDSKTQVATS--TEASSPPPT 1203
Query: 2109 PESFKTSRSSKQRLKIPLVKVDMKEEPLAVSKLTRTSGETTQTHTEPTGDSKSIKAFKES 2168
E S+ PL + ++ P+A S+ + S T T T +++ + +
Sbjct: 1204 AEVTSMPTSTPGERSTPLTSMPVRHTPVASSEASTLSTSPVDTSTPVTTSAETSSSPTTA 1263
Query: 2169 PKQILDPAASVTGSRRQLRTRKEKARALEDLVDFKELFSAPGHTEESMTIDKNTKIPCKS 2228
L + + GS L T + L + L + P T+ + + ++
Sbjct: 1264 EGTSLPTSTTSEGS--TLLTSIPVSTTLVTSPEASTLLTTPVDTKGPVV--TSNEVSSSP 1319
Query: 2229 PPPELTDTATST---KRCPKTR-PRKEVKEELSAVERLTQTSGQSTHTHKEPASGDEGIK 2284
P E T TST R P T P SA+ L+ T P +
Sbjct: 1320 TPAEGTSMPTSTYSEGRTPLTSIPVNTTLVASSAISILSTT----------PVDNSTPVT 1369
Query: 2285 VLKQRAKKKPNPVEEEPSRRRPRAPKEKAQPLEDLAGFT------ELSETSGHTQESLTA 2338
+ +P E + P E PL + T E S S ++ T
Sbjct: 1370 TSTEACS---SPTTSEGTSMPNSNPSEGTTPLTSIPVSTTPVVSSEASTLSATPVDTSTP 1426
Query: 2339 GKATKIPCESP-PLEVVDTTASTKRHLRTRVQKVQVKEEPSAVKFTQTSGETTDADKEPA 2397
G + SP E + ST +T ++ + V P A T T P
Sbjct: 1427 GTTSAEATSSPTTAEGISIPTSTPSEGKTPLKSIPVSNTPVANSEASTLSTTPVDSNSPV 1486
Query: 2398 GEDKGIKALKESAKQTPAPAASVTGSRRRPRAPRESAQAIEDLAGFKDPAAGHTEESM-T 2456
+ + S+ TPA S+ S P E + A+ + A S+ T
Sbjct: 1487 -----VTSTAVSSSPTPAEGTSIAIS-----TPSEGSTALTSIPVSTTTVASSEINSLST 1536
Query: 2457 DDKTTKIPCKSSPELEDTATSSKRRPRTRAQKVEVKEEL--LAVGKLTQTSGETTHTDKE 2514
T P + + + T++ + E L L V + S E
Sbjct: 1537 TPAVTSTPVTTYSQASSSPTTADGTSMQTSTYSEGSTPLTSLPVSTMLVVSSEANTLSTT 1596
Query: 2515 PVGEGKGTKAFKQPAKRKLDAEDVIGSRRQPRAPKEKAQPLEDLASFQELSQTPGHTEEL 2574
P+ + K A AE GS P E PL L+ P T +
Sbjct: 1597 PI-DSKTQVTASTEASSSTTAE---GSSMTISTPSE-GSPL--------LTSIPVSTTPV 1643
Query: 2575 ANGAADSFTSAPKQTPDSGKPLKISRRVLRAPKV---------------EPVGDVVSTRD 2619
A+ A + ++ P DS P+ S V +P P+ +
Sbjct: 1644 ASPEASTLSTTP---VDSNSPVITSTEVSSSPTPAEGTSMPTSTYTEGRTPLTSITVRTT 1700
Query: 2620 PVKSQSKSNTSLPPLPFKRGGGKDGSVTGTKRLRCMPAPEEIVEELPASKKQRVAPRARG 2679
PV S + S S P+ VT + R P E ++ + P
Sbjct: 1701 PVASSAISTLSTTPV------DNSTPVTTSTEARSSPTTSEGTSMPNSTPSEGTTPLTSI 1754
Query: 2680 KSSEPVVIMKRSLRTSAKRIEPAEELNSNDMKTNKEEHKLQDSVP 2724
S V+ + SA I+ + + ++ T+ S+P
Sbjct: 1755 PVSTTPVLSSEASTLSATPIDTSTPVTTSTEATSSPTTAEGTSIP 1799
Score = 65.9 bits (159), Expect = 6e-10
Identities = 360/1905 (18%), Positives = 583/1905 (30%), Gaps = 248/1905 (13%)
Query: 845 PGSKRQLQTPKEKAQALEDLAGFKELFQTPGHTEELVAAGKTTKIPCDSPQSDPVDT--- 901
PG TP E E + LF + + T +P +P + + +
Sbjct: 103 PGVSSTRMTPTESRTTSESTSDSTTLFPSSTEDTSSPTTPEGTDVPMSTPSEESISSTMA 162
Query: 902 -----PTSTKQRPKRSIRKADVEGELLAC--RNLMPSAGKAMHTPKPSVGEEKDIIIFVG 954
P + + K D+ L + P+ ++ PK + E + +
Sbjct: 163 FVSTAPLPSFEAYTSLTYKVDMSTPLTTSTQASSSPTTPESTTIPKSTNSEGSTPLTSMP 222
Query: 955 TPVQKLDLTENLTGSKRRPQTPKE-------EAQALEDLTGFKELFQTPGHTEEAVAAGK 1007
K+ +E +T TP E AQA T + P + A + G
Sbjct: 223 ASTMKVASSEAIT----LLTTPVEISTPVTISAQASSSPT----TAEGPSLSNSAPSGGS 274
Query: 1008 T--TKMPCE------------SSPPESADTPTSTRRQPKTPLEKRDVQKELSALKKLTQT 1053
T T+MP S+ P + + P T T E +++ T T
Sbjct: 275 TPLTRMPLSVMLVVSSEASTLSTTPAATNIPVIT----STEASSSPTTAEGTSIPTSTYT 330
Query: 1054 SGETTHTDKVPGGEDKSINAFRETAKQKLDPAASVTGSKRHPKTKEKAQPLEDLAGLKEL 1113
G T T + + + +D + VT S A+ L
Sbjct: 331 EGSTPLTSTPASTMPVATSEMSTLSITPVDTSTLVTTSTEPSSLPTTAEATSMLTSTLSE 390
Query: 1114 FQTPVCTDKPTTHEKTTKIACRSQPDPVDTPTSSKPQSKRSLRKVDVEEEFFALRKRTPS 1173
TP+ +T + A + PVD+ T S+ S E+ ++ TPS
Sbjct: 391 GSTPLTNMPVSTILVASSEASTTSTIPVDSKTFVTTASEASSSPTTAEDT--SIATSTPS 448
Query: 1174 AGKAMHTPKP------AVSGEKNIYAFMGTPV-QKLDLTENLTGS---------KRRLQT 1217
G T P A S N+ TPV K +T + S T
Sbjct: 449 EGSTPLTSMPVSTTPVASSEASNLST---TPVDSKTQVTTSTEASSSPPTAEVNSMPTST 505
Query: 1218 PKEKAQALEDL-------AGFKELFQTRGHTEESMTNDKTAKVACKSSQPDPDKNPASSK 1270
P E + L + A + + + S +++ + S+ P+ P S+
Sbjct: 506 PSEGSTPLTSMSVSTMPVASSEASTLSTTPVDTSTPVTTSSEASSSSTTPEGTSIPTSTP 565
Query: 1271 RRLKTSLGKVGVKEELLAVGKLTQTSGETTHTHT-----------EPTGDGKSMKAFMES 1319
T L + V L+ + + TS ++T T +G SM S
Sbjct: 566 SEGSTPLTNMPVSTRLVVSSEASTTSTTPADSNTFVTTSSEASSSSTTAEGTSMPTSTYS 625
Query: 1320 PKQILDSAASLTGSKRQLRTPKGKSEVPEDLAGFIELFQTPSHTKESMTNEKTTKVSYRA 1379
+ ++ S++ + S P D TP T T+ TT
Sbjct: 626 ERGTTITSMSVSTTLVASSEASTLSTTPVD-------SNTPVTTSTEATSSSTTAEGTSM 678
Query: 1380 SQPDLVDTPTSSKPQPKRSLRKADTEEEFLA---FRKQTPSAGKAMHTPKPAVGEEKDIN 1436
+ T P + A +E L+ TP + P + +
Sbjct: 679 PTSTYTEGSTPLTSMPVNTTLVASSEASTLSTTPVDTSTPVTTSTEASSSPTTADGASMP 738
Query: 1437 TFLGTPVQKLDQPGNLPGSNRRLQTRKEKAQALEEL-TGFRELFQTPCTDNPTTDEKTTK 1495
T TP + ++P S L + + + L T T + +PTT E T+
Sbjct: 739 T--STPSEGSTPLTSMPVSKTLLTSSEASTLSTTPLDTSTHITTSTEASCSPTTTEGTSM 796
Query: 1496 KILCKSPQS------DPADTPTNTKQRPKRSLKKADVEEEFLAFRKL----TPSAGKAMH 1545
I S S + TP + + S D ++ TP+ G +M
Sbjct: 797 PISTPSEGSPLLTSIPVSITPVTSPEASTLSTTPVDSNSPVTTSTEVSSSPTPAEGTSMP 856
Query: 1546 TPKAAVGEEKDINTFVGTPV---EKLDLLGNLPGSKRRPQTPKEKAKALEDLA-GFKELF 1601
T + G + V T + + L P P T +A++ + G
Sbjct: 857 TSTYSEGRTPLTSMPVSTTLVATSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPT 916
Query: 1602 QTPGHTEESMTDDKITEVSCKSPQPDPVKTPTSSKQRLKISLGKVGVKEEVLPVGKLTQT 1661
TPG +T PD TP S + +S PV T
Sbjct: 917 STPGEGSTPLTS-----------MPDST-TPVVSSEARTLS---------ATPVDTSTPV 955
Query: 1662 SGKTTQTHRETAGDGKSIKAFKESAKQMLDPANYGTGMERWPRTPKEEAQSLEDLAGFKE 1721
+ T T T +G SI S GT TP L E
Sbjct: 956 TTSTEATSSPTTAEGTSIPTSTPSE---------GT-------TPLTSTPVSHTLVANSE 999
Query: 1722 LFQTPDHTEESTTDDKTTKIACKSPPP--ESMDTPTSTRRRPKTPLGKRDIVEELSALKQ 1779
T T + TT SPPP E PTST TPL + + + A
Sbjct: 1000 A-STLSTTPVDSNTPLTTSTEASSPPPTAEGTSMPTSTPSEGSTPLTRMPVSTTMVA--- 1055
Query: 1780 LTQTTHTDKVPGDEDKGINVFRETAKQK--LDPAASVTGSKRQPRTPKGKAQPLEDLAGL 1837
++T+ P D + + + + D + T + + TP L
Sbjct: 1056 SSETSTLSTTPADTSTPVTTYSQASSSSTTADGTSMPTSTYSEGSTPLTSVPVSTRLVVS 1115
Query: 1838 KE---LFQTPICTDKPTTHEKTTKIACRSPQPDPVGTPTIFKPQSKRSLRKADVEEESLA 1894
E L TP+ T P TT S GT P S+ + A + +
Sbjct: 1116 SEASTLSTTPVDTSIPV----TTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVST-- 1169
Query: 1895 LRKRTPSVGKAMDTPKPAGGDEK-----DMKAFMGTPVQKL-DLPGNLPGSKRWPQTPKE 1948
T V +T D K +A P ++ +P + PG + P T
Sbjct: 1170 ----TLVVSSEANTLSTTPVDSKTQVATSTEASSPPPTAEVTSMPTSTPGERSTPLTSMP 1225
Query: 1949 KAQALEDLAGFKELFQTPGTDKPTTDEKTTKIACKSPQPDPVDTPASTKQRPKRNLRKAD 2008
+ L +P D T + + + + P ST L
Sbjct: 1226 VRHTPVASSEASTLSTSP-VDTSTPVTTSAETSSSPTTAEGTSLPTSTTSEGSTLLTSIP 1284
Query: 2009 VEEEFLALRKRTPSAGKAMDTPKPAVSDEKNINTFVETPVQKLDLLGNLPGSKRQPQTPK 2068
V + + + +DT P V+ + ++ TP + + + R P T
Sbjct: 1285 VSTTLVTSPEASTLLTTPVDTKGPVVTSNEVSSS--PTPAEGTSMPTSTYSEGRTPLTSI 1342
Query: 2069 EKAEALEDLVGFKELFQTPGHTEESMTDDKITEVSCKSP-QPESFKTSRSSKQRLKIPLV 2127
L L TP +T TE +C SP E S+ PL
Sbjct: 1343 PVNTTLVASSAISILSTTPVDNSTPVTTS--TE-ACSSPTTSEGTSMPNSNPSEGTTPLT 1399
Query: 2128 KVDMKEEPLAVSKLTRTSGETTQTHTEPTGDSKSIKAFKESPKQILDPAASVTGSRRQLR 2187
+ + P+ S+ + S T T T +++ + + + I P ++ + + L+
Sbjct: 1400 SIPVSTTPVVSSEASTLSATPVDTSTPGTTSAEATSS-PTTAEGISIPTSTPSEGKTPLK 1458
Query: 2188 TRKEKARALEDLVDFKELFSAPGHTEESMTIDKNTKIPCKSPPPELTDTATSTKRCP--- 2244
+ + + P E+ T+ + P S P +T TA S+ P
Sbjct: 1459 S--------------IPVSNTPVANSEASTL---STTPVDSNSPVVTSTAVSSSPTPAEG 1501
Query: 2245 -----KTRPRKEVKEELSAVERLTQTSGQSTHTHKEPASGDEGIKVLKQRAKKKPNPVEE 2299
T V T S + PA + Q + +P
Sbjct: 1502 TSIAISTPSEGSTALTSIPVSTTTVASSEINSLSTTPAVTSTPVTTYSQASS---SPTTA 1558
Query: 2300 EPSRRRPRAPKEKAQPLEDLAGFT------ELSETSGHTQESLTAGKATKIPCESPPLEV 2353
+ + + E + PL L T E + S +S T A+ S E
Sbjct: 1559 DGTSMQTSTYSEGSTPLTSLPVSTMLVVSSEANTLSTTPIDSKTQVTASTEASSSTTAEG 1618
Query: 2354 VDTTASTKRHLRTRVQKVQVKEEPSAVKFTQTSGETTDADKEPAGEDKGIKALKESAKQT 2413
T ST + + V P A T T P I + + S+ T
Sbjct: 1619 SSMTISTPSEGSPLLTSIPVSTTPVASPEASTLSTTPVDSNSPV-----ITSTEVSSSPT 1673
Query: 2414 PAPAASV-TGSRRRPRAPRESAQA-IEDLAGFKDPAAGHTEESMTDDKTTKIPCKSSPEL 2471
PA S+ T + R P S +A T + TT +SSP
Sbjct: 1674 PAEGTSMPTSTYTEGRTPLTSITVRTTPVASSAISTLSTTPVDNSTPVTTSTEARSSPTT 1733
Query: 2472 EDTATSSKRRPRTRAQKVEVKEELLAVGKLTQTSGETTHTDKEPVGEGKGTKAFKQPAKR 2531
+ + P LT TT PV + + P
Sbjct: 1734 SEGTSMPNSTPSE------------GTTPLTSIPVSTT-----PVLSSEASTLSATPIDT 1776
Query: 2532 KLDAEDVIGSRRQPRAPKEKAQPLEDLA-SFQELSQTPGHTEELANGAADSFTSAPKQTP 2590
+ P + + P L+ L+ TP +AN A + ++ P
Sbjct: 1777 STPVTTSTEATSSPTTAEGTSIPTSTLSEGMTPLTSTPVSHTLVANSEASTLSTTP---V 1833
Query: 2591 DSGKPLKISRRVLRAPKVEPVGDVVSTRDPVKSQSKSNTSLPPLP 2635
DS P+ S V +P G ++T P S+ +T+L +P
Sbjct: 1834 DSNSPVVTSTAVSSSP-TPAEGTSIATSTP----SEGSTALTSIP 1873
Score = 58.9 bits (141), Expect = 7e-08
Identities = 458/2507 (18%), Positives = 770/2507 (30%), Gaps = 331/2507 (13%)
Query: 64 SSTNPTQVNGSVIDEPVRLKHGDVITIIDRSFRYENESLQNGRKSTEFPRKIREQEPARR 123
+S++PT G+ + + ++T I S + + ST + + P
Sbjct: 1256 TSSSPTTAEGTSLPTSTTSEGSTLLTSIPVS----TTLVTSPEASTLLTTPVDTKGPV-- 1309
Query: 124 VSRSSFSSDPDESEGIPLKRRRVSFGGHLRPELFDENLPPNTPLKRGEA----------- 172
V+ + SS P +EG + S G R L ++P NT L A
Sbjct: 1310 VTSNEVSSSPTPAEGTSMPTSTYSEG---RTPL--TSIPVNTTLVASSAISILSTTPVDN 1364
Query: 173 --PTKRKSLVMHTPPVLKKIIKEQPQPSGKQESGSEIHVEVKAQSLVISPPAPSPRKTPV 230
P + +P + PS + I V V+S A + TPV
Sbjct: 1365 STPVTTSTEACSSPTTSEGTSMPNSNPSEGTTPLTSIPVSTTP---VVSSEASTLSATPV 1421
Query: 231 ASDQRRRSCKTAPASSSKSQ-----TEVPKRGGRKSGNLPSKRVSISRSQHDILQMI--- 282
+ + A +S + ++ T P G ++P ++ S+ L
Sbjct: 1422 DTSTPGTTSAEATSSPTTAEGISIPTSTPSEGKTPLKSIPVSNTPVANSEASTLSTTPVD 1481
Query: 283 ----------CSKRRSGASEANLIVAKSWADVVKLGAKQTQTKVIKHGPQRSMNKRQRRP 332
S + A ++ ++ L + T + S++
Sbjct: 1482 SNSPVVTSTAVSSSPTPAEGTSIAISTPSEGSTALTSIPVSTTTVASSEINSLSTTPAVT 1541
Query: 333 ATPKKPVGEVHSQFSTGHANSPCTIIIGKAHTEKVHVPARPYRVLN---NFISNQKMDFK 389
+TP + S +T S T + T +P V++ N +S +D K
Sbjct: 1542 STPVTTYSQASSSPTTADGTSMQTSTYSEGSTPLTSLPVSTMLVVSSEANTLSTTPIDSK 1601
Query: 390 EDLSGIAEMFKTPVKEQPQLTSTCHIAISNSENLLGKQFQGTDSGEEPLLPTSESFGGNV 449
++ E + E +T + S + S E L T+ +
Sbjct: 1602 TQVTASTEASSSTTAEGSSMTISTPSEGSPLLTSIPVSTTPVASPEASTLSTTPVDSNSP 1661
Query: 450 FFSAQNAAKQPSDKCSASPPLRRQCIRENGNVAKTPRNTYKMTSLETKTSDTETEPSKTV 509
++ + P+ S P + T R T +S + S T + S V
Sbjct: 1662 VITSTEVSSSPTPAEGTSMPTSTYTEGRTPLTSITVRTTPVASSAISTLSTTPVDNSTPV 1721
Query: 510 STANRSGRSTEFRNIQKLPVESKSEETNTEIVECILKRGQKATLLQQRREGEMKEIERPF 569
+T+ + S +P + SE T T + + + + P
Sbjct: 1722 TTSTEARSSPTTSEGTSMPNSTPSEGT-TPLTSIPVSTTPVLSSEASTLSATPIDTSTPV 1780
Query: 570 ETYKENIELKENDEKMKAMKRSRTWGQKCAPMSDLTDLKSLPDTELMKDTARGQNLLQTQ 629
T E E + + G +T L S P + + + L T
Sbjct: 1781 TTSTEATSSPTTAEGTSIPTSTLSEG--------MTPLTSTPVSHTLVANSEASTLSTTP 1832
Query: 630 DHAKAPKSEKGKITKMPCQSLQPEPINTPTHTKQQLKASLGKVGVKEELLAVGKFTRTSG 689
+ +P ++ P + E + T T + +L + V +A S
Sbjct: 1833 VDSNSPVVTSTAVSSSPTPA---EGTSIATSTPSEGSTALTSIPVSTTTVA-------SS 1882
Query: 690 ETTHTHREPAGDGKSIRTFKE--SPKQILDPAARVTGMKKWPRTPKEEAQSLEDLAGFKE 747
ET PA + T+ + S D ++ T + R P E
Sbjct: 1883 ETNTLSTTPAVTSTPVTTYAQVSSSPTTADGSSMPTSTPREGRPPLTSIPVSTTTVASSE 1942
Query: 748 L---------FQTPGPSEESMTDEKTTKIACKSPPPESVDTPTSTKQWPKRSLRKADVEE 798
+ +TP + + TT P P + T P + E
Sbjct: 1943 INTLSTTLADTRTPVTTYSQASSSPTTADGTSMPTPAYSEGSTPLTSMPLSTTLVVSSEA 2002
Query: 799 EFLALRKLTPSAGKAMLT-----PKPAGGD--EKDIKAFMGTPVQKLDLAGTL------- 844
L+ + S T P AGG + + TP+ + ++ TL
Sbjct: 2003 STLSTTPVDTSTPATTSTEGSSSPTTAGGTSIQTSTPSERTTPLAGMPVSTTLVVSSEGN 2062
Query: 845 -----PGSKRQLQTPKEKAQALEDLAGFKELFQTPGHTEELVAAGKTTKIPCDSPQSDPV 899
P + T +A + G P L+ + + P SP++ +
Sbjct: 2063 TLSTTPVDSKTQVTNSTEASSSATAEGSSMTISAPSEGSPLLTSIPLSTTPVASPEASTL 2122
Query: 900 DTPTSTKQRP---KRSIRKADVEGELLACRNLMPSAGKAMHTPKP---SVGEEKDIIIFV 953
T P + + + E + + S + T P +V I
Sbjct: 2123 STTPVDSNSPVITSTEVSSSPIPTEGTSMQTSTYSDRRTPLTSMPVSTTVVASSAISTLS 2182
Query: 954 GTPVQKLDLTENLTGSKRRPQTPKEEAQAL----EDLTGFKEL--FQTPGHTEEA----- 1002
TPV N T ++ P T + + E T F + P T EA
Sbjct: 2183 TTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPSEGSTPFTSMPVSTMPVVTSEASTLSA 2242
Query: 1003 ----VAAGKTTKMPCESSPP--ESADTPTSTRRQPKTPLEKRDVQKELSALKKLTQTSGE 1056
+ TT SSP E PTST + TPL V L A +++ S
Sbjct: 2243 TPVDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGTTPLTSIPVSHTLVANSEVSTLS-- 2300
Query: 1057 TTHTDKVPGGEDKSINAFRETAKQKLDPAASVTGSKRHPKTKEKAQ-PLEDL---AGLKE 1112
TT D N T+ + P + G+ T + PL + +
Sbjct: 2301 TTPVDS---------NTPFTTSTEASSPPPTAEGTSMPTSTSSEGNTPLTRMPVSTTMVA 2351
Query: 1113 LFQTPVCTDKP--TTHEKTTKIACRSQP---DPVDTPTSSKPQSKRSLRKVDVEEEFFAL 1167
F+T + P T+ TT S P D PTS+ + L V V
Sbjct: 2352 SFETSTLSTTPADTSTPVTTYSQAGSSPTTADDTSMPTSTYSEGSTPLTSVPVSTMPVVS 2411
Query: 1168 RKRTPSAGKAMHTPKPAVSGEKNIYAFMGTPVQKLDLTENLTGSKRRLQTPKEKAQALED 1227
+ + + + T P + + + + + G+ P +
Sbjct: 2412 SEASTHSTTPVDTSTPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTPVVSS 2471
Query: 1228 LAGFKELFQTRGHTEESMTNDKTAKVACKSSQPDPDKN---PASSKRRLKTSLGKVGVKE 1284
AG L T T MT A SS P ++ P S+ T L + V
Sbjct: 2472 EAG--TLSTTPVDTSTPMTTSTEA-----SSSPTTAEDIVVPISTASEGSTLLTSIPVST 2524
Query: 1285 ELLAVGKL----------------------TQTSGETTHTHTEPTGDGKS-MKAFMESPK 1321
+A + + TS E T T +G + +++ S K
Sbjct: 2525 TPVASPEASTLSTTPVDSNSPVVTSTEISSSATSAEGTSMPTSTYSEGSTPLRSMPVSTK 2584
Query: 1322 QILDSAASL-----TGSKRQLRTPKGKSEVPEDLAGFIELFQTPSHTKESMTNEKTTKVS 1376
+ S AS + + T S P TPS S+T+ + +
Sbjct: 2585 PLASSEASTLSTTPVDTSIPVTTSTETSSSPTTAKDTSMPISTPSEVSTSLTSILVSTMP 2644
Query: 1377 YRASQPDLVDT---------PTSSKPQPKRSLRKADTEEEFLAFRKQTPSAGKAMHTPKP 1427
+S+ + T TS+ + + + + TP + T
Sbjct: 2645 VASSEASTLSTTPVDTRTLVTTSTGTSSSPTTAEGSSMPTSTPGERSTPLTNILVSTTLL 2704
Query: 1428 AVGEEK-------DINTFLGTPVQKLDQPGNLPGSNRRLQTRKEKAQALEEL-------- 1472
A E D +T + T + P G++ R+ T + + L +
Sbjct: 2705 ANSEASTLSTTPVDTSTPVTTSAEASSSPTTAEGTSMRISTPSDGSTPLTSILVSTLPVA 2764
Query: 1473 -------------TGFRELFQTPCTDNPTTDEKTTKKILCKSPQSDPADTPTNTKQRPKR 1519
T T + +PTT E T+ P S P++T T P
Sbjct: 2765 SSEASTVSTTAVDTSIPVTTSTEASSSPTTAEVTS------MPTSTPSETSTPLTSMPVN 2818
Query: 1520 SLKKADVEEEFLAFRKL---TP--SAGKAMHTPKAAVGEEKDINTFVGTPVEKLDLLGNL 1574
A E L+ + TP ++ KA +P A G I + T E LL ++
Sbjct: 2819 HTPVASSEAGTLSTTPVDTSTPVTTSTKASSSPTTAEG----IVVPISTASEGSTLLTSI 2874
Query: 1575 PGSKRRPQTPKEKAKALEDLAGFKELFQTPGHTEESMTDDKITEVSCKSPQPDPVKTPTS 1634
P S TP ++A L TP T +T TE S + P S
Sbjct: 2875 PVS----TTPVASSEA-------STLSTTPVDTSIPVTTS--TEGSSSPTTAEGTSMPIS 2921
Query: 1635 SKQRLKISLGKVGVKEEVLPV----GKLTQTSGKTTQTHRETAGDGKSIKAFKESAKQML 1690
+ + L + V +PV T+ T+T T+ + S E +
Sbjct: 2922 TPSEVSTPLTSILV--STVPVAGSEASTLSTTPVDTRTPVTTSAEASSSPTTAEGTSMPI 2979
Query: 1691 DPANYGTGMERWPRTPKEEAQSLEDLAGFKELFQTPDHTEESTTDDKTTKIACKSPP--P 1748
G R P T + S+ + T T T+ TT S P
Sbjct: 2980 ST----PGERRTPLT----SMSVSTMPVASSEASTLSRTPADTSTPVTTSTEASSSPTTA 3031
Query: 1749 ESMDTPTSTRRRPKTPLGKRDIVEELSALKQLTQTTHTDKVPGDEDKGINVFRETAKQKL 1808
E P ST TPL + A+ + + + T P D +
Sbjct: 3032 EGTGIPISTPSEGSTPLTSIPVSTTPVAIPEASTLSTT---PVDSN-------------- 3074
Query: 1809 DPAASVTGSKRQPRTPKGKAQPLEDLA-GLKELFQTPICTDKPTTHEKTTKIACRSPQPD 1867
P + T P +G + P+ + G L P+ T T ++ I+ S P
Sbjct: 3075 SPVVTSTEVSSSPTPAEGTSMPISTYSEGSTPLTGVPVSTTPVT----SSAISTLSTTPV 3130
Query: 1868 PVGTPTIFKPQSKRSLRKADVEEESLALRKRTPSVGKAMDTPKPAGG---DEKDMKAFMG 1924
TP ++ S E ++ TPS G T P +
Sbjct: 3131 DTSTPVTTSTEAHSS----PTTSEGTSMPTSTPSEGSTPLTYMPVSTMLVVSSEDSTLSA 3186
Query: 1925 TPVQKLDLPGNLPGSKRWPQTPKEKAQALEDLAGFKELFQTPGTDKPTTDEKTTKIACKS 1984
TPV + P + T A+ TP T P ++
Sbjct: 3187 TPVDT-----STPVTTSTEATSSTTAEGTSIPTSTPSEGMTPLTSVPVSNTPVASSEASI 3241
Query: 1985 PQPDPVD--TPASTKQRPKRNLRKADVEEEFLALRKRTPSAGKAMDTPKP------AVSD 2036
PVD TP +T + A E ++ TPS G T P A S+
Sbjct: 3242 LSTTPVDSNTPLTTSTEASSSPPTA----EGTSMPTSTPSEGSTPLTSMPVSTTTVASSE 3297
Query: 2037 EKNINTF---VETPVQKLDLLGNLP----GSKRQPQTPKEKAEALEDLVGFKELFQTPGH 2089
++T TPV + P G+ T E + L ++ TP
Sbjct: 3298 TSTLSTTPADTSTPVTTYSQASSSPPIADGTSMPTSTYSEGSTPLTNM----SFSTTPVV 3353
Query: 2090 TEESMTDDKITEVSCKSPQPESFKTSRS--SKQRLKIPLVKVDMKEEPLAVSKLTRTSGE 2147
+ E+ T T V +P S + S S + + IP PLA ++ T
Sbjct: 3354 SSEAST-LSTTPVDTSTPVTTSTEASLSPTTAEGTSIPTSSPSEGTTPLASMPVSTTPVV 3412
Query: 2148 TTQTHTEPTGDSKSIKAFKESPKQILDPAASVTGSRRQLRTRKEKARALEDL-VDFKELF 2206
+++ +T T S S + P + G+ T E + L + + +
Sbjct: 3413 SSEVNTLSTTPVDSNTLVTTSTEASSSPTIA-EGTSLPTSTTSEGSTPLSIMPLSTTPVA 3471
Query: 2207 SAPGHTEESMTIDKNTKIPCKSPPPELTDTATSTKRCPKTRPRKEVKEELSAVERLTQTS 2266
S+ T + +D +T + SP TA T T V S
Sbjct: 3472 SSEASTLSTTPVDTSTPVTTSSPTNSSPTTAEVTSMPTSTAGEGSTPLTNMPVSTTPVAS 3531
Query: 2267 GQSTHTHKEPASGDEGIKVLKQRAKKKPNPVEEEPSRRRPRAPKEKAQPLED-LAGFTEL 2325
+++ P + + Q + +P + + R P E + L L T +
Sbjct: 3532 SEASTLSTTPVDSNTFVTSSSQASS---SPATLQVTTMRMSTPSEGSSSLTTMLLSSTYV 3588
Query: 2326 SETSGHTQESLTAGKATKIPCES------PPLEVVDTTASTKRHLRT 2366
+ + T + + ++T + + P EV+ ST + T
Sbjct: 3589 TSSEASTPSTPSVDRSTPVTTSTQSNSTPTPPEVITLPMSTPSEVST 3635
Score = 56.2 bits (134), Expect = 5e-07
Identities = 333/1725 (19%), Positives = 529/1725 (30%), Gaps = 269/1725 (15%)
Query: 492 TSLETKTSDTETEPSKTVSTANRSGRSTEFRNIQKLPVESKSEETN-TEIVECILKRGQK 550
TS++T T T P + + S+E + PV+SK++ TN TE G
Sbjct: 2032 TSIQTSTPSERTTPLAGMPVSTTLVVSSEGNTLSTTPVDSKTQVTNSTEASSSATAEGSS 2091
Query: 551 ATLLQQRREGEMKEIERPFET---------------YKENIELKENDEKMKAMKRSRTWG 595
T+ EG P T N + + E + +
Sbjct: 2092 MTI-SAPSEGSPLLTSIPLSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSPIPTEGTS 2150
Query: 596 QKCAPMSDL-TDLKSLPDTELMKDTARGQNLLQTQDHAKAPKSEKGKITKMPCQSLQPEP 654
+ + SD T L S+P + + ++ L T P + + P S E
Sbjct: 2151 MQTSTYSDRRTPLTSMPVSTTVVASSAISTLSTTPVDTSTPVTNSTEARSSPTTS---EG 2207
Query: 655 INTPTHTKQQLKASLGKVGVKEELLAVGKFTRTSGETTHTHREPAGDGKSIRTFKESPKQ 714
+ PT T + + V + + + S T ++ + +
Sbjct: 2208 TSMPTSTPSEGSTPFTSMPVSTMPVVTSEASTLSATPVDTSTPVTTSTEATSSPTTAEGT 2267
Query: 715 ILDPAARVTGMKKWPRTPKEEAQSLEDLAGFKELFQTPGPSEESMTDEKTTKIACKSPPP 774
+ + G P T + +L + L TP S T T SPPP
Sbjct: 2268 SIPTSTLSEGTT--PLTSIPVSHTLVANSEVSTLSTTPVDSNTPFT----TSTEASSPPP 2321
Query: 775 --ESVDTPTSTKQWPKRSLRKADVEEEFLALRKLTPSAGKAMLTPKPAGGDEKDIKAFMG 832
E PTST L + V +A S + L+ PA
Sbjct: 2322 TAEGTSMPTSTSSEGNTPLTRMPVSTTMVA------SFETSTLSTTPAD---------TS 2366
Query: 833 TPVQKLDLAGTLPGSKRQLQTPKEKAQALEDLAGFKELFQTPGHTEELVAAGKTTKIPCD 892
TPV AG+ P + P G L P T +V++ +T
Sbjct: 2367 TPVTTYSQAGSSPTTADDTSMPTSTYSE-----GSTPLTSVPVSTMPVVSSEASTH---- 2417
Query: 893 SPQSDPVDTPTSTKQRPKRSIRKADVEGELLAC----RNLMPSAGKAMHTPKPSVGEEKD 948
+ PVDT T + S EG + P A + T P V E
Sbjct: 2418 --STTPVDTSTPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTT-PVVSSEAG 2474
Query: 949 IIIFVGTPVQKLDLTENLTGSKRRPQTPKEEAQALEDLTGFKELFQ------TPGHTEEA 1002
+ TPV T + P T ++ + + L TP + EA
Sbjct: 2475 TLST--TPVDTSTPMTTSTEASSSPTTAEDIVVPISTASEGSTLLTSIPVSTTPVASPEA 2532
Query: 1003 VAAGKT-----------TKMPCESSPPESADTPTSTRRQPKTPLEKRDV------QKELS 1045
T T++ ++ E PTST + TPL V E S
Sbjct: 2533 STLSTTPVDSNSPVVTSTEISSSATSAEGTSMPTSTYSEGSTPLRSMPVSTKPLASSEAS 2592
Query: 1046 ALKKL-------------TQTSGETTHTDKVPGGEDKSINAFRETAKQKLDPAAS----- 1087
L T +S T +P ++ + P AS
Sbjct: 2593 TLSTTPVDTSIPVTTSTETSSSPTTAKDTSMPISTPSEVSTSLTSILVSTMPVASSEAST 2652
Query: 1088 --------------VTGSKRHPKTKEKAQPLEDLAGLKELFQTPVCTDKPTTHEKTTKIA 1133
TG+ P T E + G + TP+ +T A
Sbjct: 2653 LSTTPVDTRTLVTTSTGTSSSPTTAEGSSMPTSTPGER---STPLTNILVSTTLLANSEA 2709
Query: 1134 CRSQPDPVDTPTSSKPQSKRSLRKVDVEEEFFALRKRTPSAGKA-----MHTPKPAVSGE 1188
PVDT T ++ S E ++R TPS G + + P S E
Sbjct: 2710 STLSTTPVDTSTPVTTSAEASSSPTTAEGT--SMRISTPSDGSTPLTSILVSTLPVASSE 2767
Query: 1189 KNIYA--FMGTPVQKLDLTENLTG------SKRRLQTPKEKAQALEDL-AGFKELFQTRG 1239
+ + + T + TE + + TP E + L + + +
Sbjct: 2768 ASTVSTTAVDTSIPVTTSTEASSSPTTAEVTSMPTSTPSETSTPLTSMPVNHTPVASSEA 2827
Query: 1240 HTEESMTNDKTAKVACK---SSQPDPDKN---PASSKRRLKTSLGKVGVKEELLA---VG 1290
T + D + V SS P + P S+ T L + V +A
Sbjct: 2828 GTLSTTPVDTSTPVTTSTKASSSPTTAEGIVVPISTASEGSTLLTSIPVSTTPVASSEAS 2887
Query: 1291 KLTQTSGETT---HTHTE-----PTGDGKSMKAFMESP-----KQILDSAASLTGSKR-- 1335
L+ T +T+ T TE T +G SM S IL S + GS+
Sbjct: 2888 TLSTTPVDTSIPVTTSTEGSSSPTTAEGTSMPISTPSEVSTPLTSILVSTVPVAGSEAST 2947
Query: 1336 ------QLRTP----KGKSEVPEDLAGFIELFQTPSHTKESMTNEKTTKVSYRASQPD-L 1384
RTP S P G TP + +T+ + + +S+ L
Sbjct: 2948 LSTTPVDTRTPVTTSAEASSSPTTAEGTSMPISTPGERRTPLTSMSVSTMPVASSEASTL 3007
Query: 1385 VDTP--TSSKPQPKRSLRKADTEEEFLAFRKQTPSAGKAMHTPKP------AVGEEKDIN 1436
TP TS+ + T E TPS G T P A+ E ++
Sbjct: 3008 SRTPADTSTPVTTSTEASSSPTTAEGTGIPISTPSEGSTPLTSIPVSTTPVAIPEASTLS 3067
Query: 1437 T----------------FLGTPVQKLDQP------GNLPGSNRRLQTRKEKAQALEELTG 1474
T TP + P G+ P + + T + A+ L+
Sbjct: 3068 TTPVDSNSPVVTSTEVSSSPTPAEGTSMPISTYSEGSTPLTGVPVSTTPVTSSAISTLST 3127
Query: 1475 FRELFQTPCT------DNPTTDEKTTKKILCKSPQSDPADTPTNTKQRPKRSLKKADVEE 1528
TP T +PTT E T+ P S P++ T P ++ E+
Sbjct: 3128 TPVDTSTPVTTSTEAHSSPTTSEGTS------MPTSTPSEGSTPLTYMPVSTMLVVSSED 3181
Query: 1529 EFLAFRKLTPSAGKAMHTPKAAVGEEKDINTFVGTPVEKLDLLGNLPGSKRRPQTPKEKA 1588
L+ + S T + + + TP E + L ++P S TP +
Sbjct: 3182 STLSATPVDTSTPVTTSTEATSSTTAEGTSIPTSTPSEGMTPLTSVPVS----NTPVASS 3237
Query: 1589 KALEDLAGFKELFQTPGHTEESMTDDKITEVSCKSPQPDPVKTPTSSKQRLKISLGKVGV 1648
+A L TP + +T TE S P + PTS+ L
Sbjct: 3238 EA-------SILSTTPVDSNTPLTTS--TEASSSPPTAEGTSMPTSTPSEGSTPLTS--- 3285
Query: 1649 KEEVLPVGKLTQTSGKTTQTHRETAGDGKSIKAFKESAKQMLDPANYGTGMERWPRTPKE 1708
+PV T S +T+ A + + +++ P GT M T E
Sbjct: 3286 ----MPVSTTTVASSETSTLSTTPADTSTPVTTYSQASSS--PPIADGTSMP--TSTYSE 3337
Query: 1709 EAQSLEDLAGFKELFQTPDHTEESTTDDKTTKIACKSPPPESMDTPTSTRRRPKTPLGKR 1768
+ L +++ F T + TT + +P S + S T +
Sbjct: 3338 GSTPLTNMS-----FSTTPVVSSEASTLSTTPVDTSTPVTTSTEASLSPTTAEGTSIPTS 3392
Query: 1769 DIVEELSALKQLTQTTHTDKVPGDEDKGINVFRETAKQKLDPAASVTGSKRQPRTPKGKA 1828
E + L + +T T V + +N T + T + P +G +
Sbjct: 3393 SPSEGTTPLASMPVST-TPVVSSE----VNTLSTTPVDSNTLVTTSTEASSSPTIAEGTS 3447
Query: 1829 QPLEDLA-GLKELFQTPICTDKPTTHEKTTKIACRSPQPDPVGTPTIFKPQSKRSLRKAD 1887
P + G L P+ T + E +T S P TP + S A+
Sbjct: 3448 LPTSTTSEGSTPLSIMPLSTTPVASSEAST----LSTTPVDTSTPVTTSSPTNSSPTTAE 3503
Query: 1888 VEE--ESLALRKRTPSVGKAMDTPKPAGGDEK-------DMKAFMGTPVQKLDLPGNLPG 1938
V S A TP + T A + D F+ + Q P L
Sbjct: 3504 VTSMPTSTAGEGSTPLTNMPVSTTPVASSEASTLSTTPVDSNTFVTSSSQASSSPATLQV 3563
Query: 1939 SKRWPQTPKEKAQALEDL--------AGFKELFQTPGTDKPTTDEKTTKIACKSPQPDPV 1990
+ TP E + +L + + TP D+ T +T+ P+ +
Sbjct: 3564 TTMRMSTPSEGSSSLTTMLLSSTYVTSSEASTPSTPSVDRSTPVTTSTQSNSTPTPPEVI 3623
Query: 1991 DTPASTKQRPKRNLRKADVEEEFLALRKRTPSAGKAMDTPKPAVS 2035
P ST L V + + + ++ +DT P ++
Sbjct: 3624 TLPMSTPSEVSTPLTIMPVSTTSVTISEAGTASTLPVDTSTPVIT 3668
Score = 50.1 bits (118), Expect = 3e-05
Identities = 298/1496 (19%), Positives = 463/1496 (30%), Gaps = 239/1496 (15%)
Query: 484 TPRNTYKMTSLETKTSDTETEPSKTVSTANRSGRSTEFRNIQKLPVESKSEETNTEIVEC 543
TP TY T+D + P+ T S + S + + E+ + T
Sbjct: 2367 TPVTTYSQAGSSPTTADDTSMPTSTYSEGSTPLTSVPVSTMPVVSSEASTHSTTPVDTST 2426
Query: 544 ILKRGQKATLLQQRREGEMKEIERPFETYKENIELKENDEKM---KAMKRSRTWGQKCAP 600
+ +A+ EG P E + + + +A S T P
Sbjct: 2427 PVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTPVVSSEAGTLSTTPVDTSTP 2486
Query: 601 MSDLTDLKSLPDTE-----LMKDTARGQNLLQTQDHAKAP--KSEKGKITKMPCQSLQP- 652
M+ T+ S P T + + G LL + + P E ++ P S P
Sbjct: 2487 MTTSTEASSSPTTAEDIVVPISTASEGSTLLTSIPVSTTPVASPEASTLSTTPVDSNSPV 2546
Query: 653 -------------EPINTPTHTKQQLKASLGKVGVKEELLAVGKFTRTSGETTHTHREPA 699
E + PT T + L + V + LA S E + P
Sbjct: 2547 VTSTEISSSATSAEGTSMPTSTYSEGSTPLRSMPVSTKPLA-------SSEASTLSTTPV 2599
Query: 700 GDGKSIRTFKE---SPKQILDPAARVTGMKKWPRTPKEEAQSLEDLAGFKELFQTPGPSE 756
+ T E SP D + ++ TP E + SL + + P S
Sbjct: 2600 DTSIPVTTSTETSSSPTTAKDTSMPIS-------TPSEVSTSLTSIL----VSTMPVASS 2648
Query: 757 ESMT------DEK---TTKIACKSPP--PESVDTPTSTKQWPKRSLRKADVEEEFLA--- 802
E+ T D + TT S P E PTST L V LA
Sbjct: 2649 EASTLSTTPVDTRTLVTTSTGTSSSPTTAEGSSMPTSTPGERSTPLTNILVSTTLLANSE 2708
Query: 803 --LRKLTP--------SAGKAMLTPKPAGGDEKDIK--AFMGTPVQKLDLAGTLPGSKRQ 850
TP ++ +A +P A G I + TP+ + L TLP + +
Sbjct: 2709 ASTLSTTPVDTSTPVTTSAEASSSPTTAEGTSMRISTPSDGSTPLTSI-LVSTLPVASSE 2767
Query: 851 LQTPKEKAQALEDLAGFKELFQTPGHTEELVAAGKTTKIPCDSPQSDPVDTPTSTKQRPK 910
T A P T ++ TT P S P +T T P
Sbjct: 2768 ASTVSTTAVDT----------SIPVTTSTEASSSPTTAEVTSMPTSTPSETSTPLTSMPV 2817
Query: 911 RSIRKADVEGELLACRNL-----MPSAGKAMHTPKPSVGEEKDIIIFVGTPVQKLDLTEN 965
A E L+ + + ++ KA +P + G I++ + T + L +
Sbjct: 2818 NHTPVASSEAGTLSTTPVDTSTPVTTSTKASSSPTTAEG----IVVPISTASEGSTLLTS 2873
Query: 966 LTGSKRRPQTPKEEAQALEDLTGFKELFQTPGHTEEAVAAGKTTKMPCESSP--PESADT 1023
+ S TP ++A L TP T V TT SSP E
Sbjct: 2874 IPVS----TTPVASSEA-------STLSTTPVDTSIPV----TTSTEGSSSPTTAEGTSM 2918
Query: 1024 PTSTRRQPKTPLEKRDVQKELSALKKLTQTSGETTHTD-KVPGGEDKSINAFRETAKQKL 1082
P ST + TPL V A + + S TT D + P ++ TA+
Sbjct: 2919 PISTPSEVSTPLTSILVSTVPVAGSEASTLS--TTPVDTRTPVTTSAEASSSPTTAEGTS 2976
Query: 1083 DPAASVTGSKRHPKTKEKAQPLEDLAGLKELFQTPVCTDKPTTHEKTTKIACRSQPDPVD 1142
P S G +R P T + PV + + +T +T A S P
Sbjct: 2977 MP-ISTPGERRTPLTSMSVSTM------------PVASSEASTLSRTP--ADTSTPVTTS 3021
Query: 1143 TPTSSKPQSKRSLRKVDVEEEFFALRKRTPSAGKAMHTPKPAVSGEKNIYAFMGTPVQKL 1202
T SS P + E + TPS G T P + I +
Sbjct: 3022 TEASSSPTT----------AEGTGIPISTPSEGSTPLTSIPVSTTPVAIPEASTLSTTPV 3071
Query: 1203 DLTENLTGSKRRLQTPKEKAQALEDLAGFKELFQTRGHTEESMTNDKTAKVACKSSQPDP 1262
D + S +P ++ + E S T ++ ++ S+ P
Sbjct: 3072 DSNSPVVTSTEVSSSPTPAEGTSMPISTYSEGSTPLTGVPVSTTPVTSSAISTLSTTPVD 3131
Query: 1263 DKNPASSKRRLKTSLGKVGVKEELLAVGKLTQTSGETTHTHTEPTGDGKSMKAFMESPKQ 1322
P ++ +S T+ E T T +G + +M
Sbjct: 3132 TSTPVTTSTEAHSS-----------------PTTSEGTSMPTSTPSEGSTPLTYMPVSTM 3174
Query: 1323 ILDSAASLTGSKRQLRTPKGKSEVPEDLA-----GFIELFQTPSHTKESMTNEKTTKVSY 1377
++ S+ T S + T + E + G TPS +T+ +
Sbjct: 3175 LVVSSEDSTLSATPVDTSTPVTTSTEATSSTTAEGTSIPTSTPSEGMTPLTSVPVSNTPV 3234
Query: 1378 RASQPDLVDTPTSSKPQPKRSLRKADTE---EEFLAFRKQTPSAGKAMHTPKP------A 1428
+S+ ++ T P + +A + E + TPS G T P A
Sbjct: 3235 ASSEASILSTTPVDSNTPLTTSTEASSSPPTAEGTSMPTSTPSEGSTPLTSMPVSTTTVA 3294
Query: 1429 VGEEKDINTF---LGTPVQKLDQPGNLP----GSNRRLQTRKEKAQALEELTGFRELFQT 1481
E ++T TPV Q + P G++ T E + L ++ T
Sbjct: 3295 SSETSTLSTTPADTSTPVTTYSQASSSPPIADGTSMPTSTYSEGSTPLTNMS----FSTT 3350
Query: 1482 PCTDNPTTDEKTTKKILCKSPQSDPADTPTNTKQRPKRSLKKADVEEEFLAFRK----LT 1537
P + + TT P DT T + SL E + T
Sbjct: 3351 PVVSSEASTLSTT-----------PVDTSTPVTTSTEASLSPTTAEGTSIPTSSPSEGTT 3399
Query: 1538 PSAGKAMHTPKAAVGEEKDINTFVGTPVEKLDLLGNLPGSKRRP------QTPKEKAKAL 1591
P A + T E +NT TPV+ L+ + P P
Sbjct: 3400 PLASMPVSTTPVVSSE---VNTLSTTPVDSNTLVTTSTEASSSPTIAEGTSLPTSTTSEG 3456
Query: 1592 EDLAGFKELFQTPGHTEESMT-----DDKITEVSCKSP-QPDPVKTPTSSKQRLKISLGK 1645
L TP + E+ T D T V+ SP P +S G
Sbjct: 3457 STPLSIMPLSTTPVASSEASTLSTTPVDTSTPVTTSSPTNSSPTTAEVTSMPTSTAGEGS 3516
Query: 1646 VGVKEEVLPVGKLTQTSGKTTQTHRETAGDGKSIKAFKESAKQMLDPANYGTGMERWPRT 1705
+ +PV T + T T D + S++ PA R T
Sbjct: 3517 TPLTN--MPV-STTPVASSEASTLSTTPVDSNTF--VTSSSQASSSPATLQVTTMRM-ST 3570
Query: 1706 PKEEAQSLEDLAGFKELFQTPDHTEESTTD-DKTTKIACKS------PPPESMDTPTSTR 1758
P E + SL + + + + ST D++T + + PPE + P ST
Sbjct: 3571 PSEGSSSLTTMLLSSTYVTSSEASTPSTPSVDRSTPVTTSTQSNSTPTPPEVITLPMSTP 3630
Query: 1759 RRPKTPLGKRDIVEELSALKQLTQTTHTDKVPGDEDKGINVFRETAKQKLDPAASVTGSK 1818
TPL I+ + +++ +P D P + T
Sbjct: 3631 SEVSTPL---TIMPVSTTSVTISEAGTASTLPVDTS--------------TPVITSTQVS 3673
Query: 1819 RQPRTPKGKAQPL-EDLAGLKELFQTPICTDKPTTHEKTTKIACRSPQPDPVGTPT 1873
P TP+G P+ G L P+ T + T+ E +T PV T T
Sbjct: 3674 SSPVTPEGTTMPIWTPSEGSTPLTTMPVSTTRVTSSEGSTLSTPSVVTSTPVTTST 3729
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 75.5 bits (184), Expect = 7e-13
Identities = 125/597 (20%), Positives = 243/597 (40%), Gaps = 54/597 (9%)
Query: 946 EKDIIIFVGTPVQKLDLTENLTGSKRRP----QTPKEEAQALEDLTGFKELFQTPGHTEE 1001
EK+ +I V ++ +TE +T + + + +EE E+ G +E ++P EE
Sbjct: 451 EKETVI-VEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPP-AEE 508
Query: 1002 AVAAGKTTKMPCESSPPESADTPTSTRRQPKTPLEKRDVQKELSALKKLTQTSGETTHTD 1061
A + K K P + A+ + + + K+P E + +K S K+ ++ E
Sbjct: 509 AASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEA---- 564
Query: 1062 KVPGGEDKSINAFRETAKQKLDPAASVTGSKRHPKTKEKAQPLEDLAGLKELFQTPVCTD 1121
K P E+ A ++ ++ PA S K+ EKA+ + +KE ++P
Sbjct: 565 KSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAK-----SPVKEEAKSPAEAK 619
Query: 1122 KPTTHEKTTKIACRSQPDPVDTPTSSKPQSKRSLRKVDVEEEFFALRKRTPSAGKAMHTP 1181
P E + +S P+ +PT + +S + + EE + ++P +A +P
Sbjct: 620 SPVKEEAKSPAEVKS-PEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEA-KSP 677
Query: 1182 KPAVSGEKNIYAFMGTPVQKLDLTENLTGSKRRLQTP-KEKAQALEDLAGFKELFQTRGH 1240
+ A S K A +P + + S + ++P KE+A++ E + +
Sbjct: 678 EKAKSPVK---AEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPE---------KAKSP 725
Query: 1241 TEESMTNDKTAKVACKSSQPDPDKNPASSKRR---LKTSLGKVGVKEELLA-VGKLTQTS 1296
+E + AK K P+K + K + +K+ K KEE + K + +
Sbjct: 726 VKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKA 785
Query: 1297 GETTHTHTEPTGDGKS-MKAFMESPKQILDSAASLTGSKRQLRTPKG-KSEVPEDLAGFI 1354
+ KS +K ++P++ + + ++ P+ K + P A
Sbjct: 786 KSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEE 845
Query: 1355 ELFQTPSHTKESMTNEKTTKVSYRASQPDLVDTPTSSKPQPKRSLRKADTEEEFLAFRKQ 1414
+ TP T+E ++K A +P + + + +PK S K + ++E +K+
Sbjct: 846 KAPATPK-TEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKES--KVEAKKEEAEDKKK 902
Query: 1415 TPSAGKAMHTPKPAVGEEKDINTFLGTPVQKLDQPGNLPGSNRRLQTRK--EKAQALEEL 1472
P+ K PA E K+ P +K + P + + K EK +A E
Sbjct: 903 VPTPEK----EAPAKVEVKED----AKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEK 954
Query: 1473 TGFRELFQTPCTDNPTTDEKTTK--KILCK---SPQSDPADTPTNTKQRPKRSLKKA 1524
+E + P T+ K + K L K P+++ A+ ++T Q+ + +KA
Sbjct: 955 KDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKDSKPPEKA 1011
Score = 74.7 bits (182), Expect = 1e-12
Identities = 119/635 (18%), Positives = 229/635 (36%), Gaps = 68/635 (10%)
Query: 2257 SAVERLTQTSGQSTHTHKEPASGDEGIKVLKQRAKKK-------------PNPVEEEPSR 2303
S E L + STH +E IKV+++ K+ EEE
Sbjct: 421 SLPEGLPKIPSVSTHIK---VKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKE 477
Query: 2304 RRPRAPKEKAQPLEDLAGFTELSETSGHTQESLTAGKATKIPCESPPLEVVDTTASTKRH 2363
+ KE+ E+ A E S +E+ + K K P + + + K
Sbjct: 478 AKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEE 537
Query: 2364 LRTRVQKVQVKEEPSAVKFTQTSGETTDADKEPAGEDKGIKALKESAKQTPAPAASVTGS 2423
++ +VK A + ++ K P E+ A +S ++ +PA S
Sbjct: 538 AKS---PAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKS 594
Query: 2424 RRRPRAPRESAQAIEDLAGFKDPAAGHTEESMTDDKTTKIPCKSSPELEDTATSSKRRPR 2483
++P ++ +++ A A +E K P K+ ++ A S ++
Sbjct: 595 PAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKS 654
Query: 2484 TRAQKVEVKEELLAVGKLTQTSGETTHTDKEPV-GEGKGTKAFKQPAKRKLDAEDVIGS- 2541
++ + E+ + K S E K PV E K + K P K + + + S
Sbjct: 655 PEKEEAKSPEKAKSPVKAEAKSPEKA---KSPVKAEAKSPEKAKSPVKEEAKSPEKAKSP 711
Query: 2542 -RRQPRAPKEKAQPLEDLASFQELSQTPGHTEELANGAADSFTSAPKQTPDSGKPLKISR 2600
+ + ++P++ P+++ A E +++P E + A S P+ K L +
Sbjct: 712 VKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKS--------PEKAKTLDVKS 763
Query: 2601 RVLRAPKVEPVGDVV-----STRDPVKSQSKS-NTSLPPLPFKRGGGKDGSVTGTKRLRC 2654
+ P E + PVK + KS + PL K+ + K +
Sbjct: 764 PEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPL-------KEDAKAPEKEI-- 814
Query: 2655 MPAPEEI-----VEELPASKKQRVAPRARGKSSEPVVIMKRSLRTSAKRIEPAEELNSND 2709
P EE+ EE P K + P+ + P + +T K+ EE +
Sbjct: 815 -PKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPA-----TPKTEEKKDSKKEEAPKKE 868
Query: 2710 MKTNKEEHKLQDSVPENKGISLRSRRQNKTEAEQQITEVFVLAERIEINRNEKKPMKTSP 2769
K E K + +V + K + ++++ + ++ T ++E+ + K KT
Sbjct: 869 APKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKT-- 926
Query: 2770 EMDIQNPDDG----ARKPIPRDKVTENKRCLRSARQNESSQPKVAEESGGQKSAKVLMQN 2825
E+ + PDD KP + + K+ + + + + E + + +
Sbjct: 927 EVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEP 986
Query: 2826 QKGKGEAGNSDSMCLRSRKTKSQPAASTLESKSVQ 2860
K K E S + + S+P E K+ +
Sbjct: 987 SKPKAEKAEKSS---STDQKDSKPPEKATEDKAAK 1018
Score = 72.0 bits (175), Expect = 8e-12
Identities = 122/590 (20%), Positives = 225/590 (38%), Gaps = 68/590 (11%)
Query: 1707 KEEAQSLEDLAGFKELFQTPDHTEESTTDDKTTKIACKSPPPESMDTPTSTRRRPKTPLG 1766
+EE E+ G +E ++P EE+ + +K K K + + + K+P
Sbjct: 485 EEEGGEEEEAEGGEEETKSPP-AEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAE 543
Query: 1767 KRDIVEELSALKQLTQTTHTDKVPGDEDKGINVFRETAKQKLDPAASVTGSKRQPRTPKG 1826
+ + S K+ ++ K P E+ ++ + P + + +K + ++P
Sbjct: 544 VKSPEKAKSPAKEEAKSPPEAKSPEKEE------AKSPAEVKSPEKAKSPAKEEAKSPAE 597
Query: 1827 KAQPLEDLAGLKELFQTPICTDKPTTHEKTTKIACRSPQPDPVGTPTIFKPQSKRSLRKA 1886
P + + +KE ++P P E + +S P+ +PT + +S +
Sbjct: 598 AKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKS--PEKAKSPTKEEAKSPEKAKSP 655
Query: 1887 DVEEESLALRKRTPSVGKAMDTPKPAGGDEKDMKAFMGTPVQKLDLPGNLPGSKRWPQTP 1946
+ EE + ++P +A K + +KA +P +K P K ++P
Sbjct: 656 EKEEAKSPEKAKSPVKAEAKSPEKA----KSPVKAEAKSP-EKAKSP-----VKEEAKSP 705
Query: 1947 KEKAQALEDLAGFKELFQTPGTDKPTTDEKTTKIACKSPQPDPVDTPASTKQRPK-RNLR 2005
++ +++ A E ++P ++ T EK KSP + +P K K + L
Sbjct: 706 EKAKSPVKEEAKSPEKAKSPVKEEAKTPEK-----AKSPVKEEAKSPEKAKSPEKAKTLD 760
Query: 2006 KADVEEEFLALRKRTPSAGKAMDTPKPAVSDEKNINTFVETPVQKLDLLGNLPGSKRQPQ 2065
E + A + A K + K V +E ++P+
Sbjct: 761 VKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPL----------------- 803
Query: 2066 TPKEKAEALEDLVGFKELFQTPGHTEESMTDDKITEVSCK--------SPQPESFKTSRS 2117
KE A+A E + KE ++P EE + K+ E K +P+ E K S+
Sbjct: 804 --KEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKK 861
Query: 2118 SK-QRLKIPLVKVDMKEEPLAVSKLTRTSGETTQTHTEPTGDSKSIKA-FKESPKQI-LD 2174
+ + + P KV+ K+EP AV K + E + E D K + KE+P ++ +
Sbjct: 862 EEAPKKEAPKPKVEEKKEP-AVEKPKESKVEAKKEEAE---DKKKVPTPEKEAPAKVEVK 917
Query: 2175 PAASVTGSRRQLRTRKEKARALEDLVDFKELFSAPGHTEESMTIDKNTKIPCKSPPPELT 2234
A + + A+A E S P +E+ K+TK P E
Sbjct: 918 EDAKPKEKTEVAKKEPDDAKAKEP--------SKPAEKKEAAPEKKDTKEEKAKKPEEKP 969
Query: 2235 DTATSTKRCPKTRPRKEVKEELSAVERLTQTSGQSTHTHKEPASGDEGIK 2284
T K KT ++ K + E+ + T Q E A+ D+ K
Sbjct: 970 KTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTD-QKDSKPPEKATEDKAAK 1018
Score = 61.6 bits (148), Expect = 1e-08
Identities = 130/651 (19%), Positives = 241/651 (37%), Gaps = 84/651 (12%)
Query: 524 IQKLPVESKSEETNTEIVECILKRGQKATLLQQRREGEMKEIERPFETYKENIELKENDE 583
+ K+P S + +E ++++ +K T++ + + E + E E ++ + +E E
Sbjct: 426 LPKIPSVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKE 485
Query: 584 KMKAMKRSRTWGQKCAPMSDLTDLKSLPDTELMKDTARGQNLLQTQDHAKAPKSEKGKIT 643
+ + G++ + KS P E + AK+P E+ K +
Sbjct: 486 EEGGEEEEAEGGEE--------ETKSPPAEEAASP----------EKEAKSPVKEEAK-S 526
Query: 644 KMPCQSLQPEPINTPTHTKQQLKASLGKVGVKEELLAVGKFTRTSGETTHTHREPAGDGK 703
+S + E +P K KA K KEE + + E + E K
Sbjct: 527 PAEAKSPEKEEAKSPAEVKSPEKA---KSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEK 583
Query: 704 SIRTFKE---SPKQILDPAARVTGMKKWPRTPKEEAQSLEDLAGFKELFQTPGPSEESMT 760
+ KE SP + P + +K+ ++P E +++ A ++P ++
Sbjct: 584 AKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTK 643
Query: 761 DEKTTKIACKSPPPESVDTPTSTKQWPKRSLRKADVEEEFLALRKLTPSAGKAMLTPKPA 820
+E + KSP E +P K K + + + + +P K+ + + A
Sbjct: 644 EEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPV-KEEA 702
Query: 821 GGDEKDIKAFMGTPVQKLDLAGTLPGS--KRQLQTPKEKAQALEDLAGFKELFQTPGHTE 878
EK +PV++ + S K + +TP++ +++ A E ++P +
Sbjct: 703 KSPEK-----AKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAK 757
Query: 879 ELVAAGKTTKIPCDSPQSDPVDT-PTSTKQRPKRSIR-----KADVEGELLACRNLMPSA 932
L K P P D P K K ++ K+ ++ + A +P
Sbjct: 758 TLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIP-- 815
Query: 933 GKAMHTPKPSVGEEKDIIIFVGTPVQKLDLTENLTGSKRRPQTPKEEAQALEDLTGFKEL 992
K P EEK + V P +K + ++ P TPK
Sbjct: 816 -KKEEVKSPVKEEEKPQEVKVKEPPKKAE-------EEKAPATPK--------------- 852
Query: 993 FQTPGHTEEAVAAGKTTKMPCESSPPESADTPTSTRRQPKTPLEKRDVQKELSALKKLTQ 1052
TEE + K E+ P+ + +PK K + +KE + KK
Sbjct: 853 ------TEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKE--SKVEAKKEEAEDKKKVP 904
Query: 1053 TSGETTHTDKVPGGEDKSINAFRETAKQKLDPAASVTGSKRHPKTKEKAQPLEDLAGLKE 1112
T E KV ED E AK++ D A + SK P K++A P E +E
Sbjct: 905 TP-EKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSK--PAEKKEAAP-EKKDTKEE 960
Query: 1113 LFQTPVCTDKPTTHEKTTKIACRSQPDPVDTPTSSKPQSKRSLRKVDVEEE 1163
+ P +KP T K + D + SKP+++++ + +++
Sbjct: 961 KAKKP--EEKPKTEAKA------KEDDKTLSKEPSKPKAEKAEKSSSTDQK 1003
Score = 60.5 bits (145), Expect = 2e-08
Identities = 118/557 (21%), Positives = 214/557 (38%), Gaps = 64/557 (11%)
Query: 1462 RKEKAQALEELTGFRELFQTPCTDNPTTDEKTTKKILCKSPQSDPADTPTNTKQRPKRSL 1521
++E+ EE G E ++P + + EK K SP + A +P K K
Sbjct: 484 KEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAK-----SPVKEEAKSPAEAKSPEKEEA 538
Query: 1522 KK-ADVEEEFLAFRKLTPSAGKAMHTPKAAVGEEKDINTFVGTPVEKLDLLGNLPGSKRR 1580
K A+V+ A +P+ +A P+A E+++ + P E +K
Sbjct: 539 KSPAEVKSPEKA---KSPAKEEAKSPPEAKSPEKEEAKS----PAEVKSPEKAKSPAKEE 591
Query: 1581 PQTPKEKAKALEDLAGFKELFQTPGHTEESMTDDKITEVSCKSPQPDPVKTPTSSKQRLK 1640
++P E + + KE ++P + + ++ + KSP+ K+PT + +
Sbjct: 592 AKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEK--AKSPTKEEAKSP 649
Query: 1641 ISLGKVGVKEEVLPVGKLTQTSGKTTQTHRETAGDGKS-IKAFKESAKQMLDPANYGTGM 1699
K KEE K + + + ++ KS +KA +S ++ P
Sbjct: 650 -EKAKSPEKEEA----KSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKS 704
Query: 1700 ERWPRTP-KEEAQSLEDLAG-FKELFQTPDHTEESTTDDKTTKIACKSPPP------ESM 1751
++P KEEA+S E KE +TP+ + ++ + KSP +S
Sbjct: 705 PEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSP 764
Query: 1752 DTPTSTRRRPKTPL------GKRDIVEELSALKQLTQTTHTD------KVPGDEDKGINV 1799
+ T + ++P K + EE+ + ++ D ++P E+ V
Sbjct: 765 EAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPV 824
Query: 1800 FRETAKQ--KLDPAASVTGSKRQPRTPKG--KAQPLEDLAGLKELFQTPICTDKPTTHEK 1855
E Q K+ ++ P TPK K ++ A KE + + K EK
Sbjct: 825 KEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEK 884
Query: 1856 TTKIACRSPQPDPVGTPTIFKPQSKRSLRKADVEE-----ESLALRKRTPSVGKAMDTPK 1910
+ + + + + P+ K + K +V+E E + K+ P KA + K
Sbjct: 885 PKESKVEAKKEEAEDKKKVPTPE-KEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSK 943
Query: 1911 PAGGDEKDMKAFMGTPVQKLDLPGNLPGSKRWPQTPKEKAQALEDLAGFKELFQTPGTDK 1970
PA E + T +K +K+ + PK +A+A ED K L + P K
Sbjct: 944 PAEKKEAAPEK-KDTKEEK---------AKKPEEKPKTEAKAKED---DKTLSKEPSKPK 990
Query: 1971 PTTDEKTTKIACKSPQP 1987
EK++ K +P
Sbjct: 991 AEKAEKSSSTDQKDSKP 1007
Score = 60.1 bits (144), Expect = 3e-08
Identities = 126/615 (20%), Positives = 226/615 (36%), Gaps = 71/615 (11%)
Query: 2081 KELFQTPGHTEESMTDDKITEVSCKSPQPESFKT--------SRSSKQRLKIPLVKVDMK 2132
KE TEE+ +++TE K + E K + ++ K P +
Sbjct: 452 KETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAAS 511
Query: 2133 EEPLAVSKLTRTSGETTQTHTEPTGDSKSIKAFKESPKQILDPAASVTGSRRQLRT-RKE 2191
E A S + + + + ++KS K SP++ PA S + ++ KE
Sbjct: 512 PEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVK-SPEKAKSPAKEEAKSPPEAKSPEKE 570
Query: 2192 KARALEDLVDFKELFSAPGHTEESMTIDKNTKIPCKSPPPELTDTATSTKRCPKTRPRKE 2251
+A++ + V E +P E K P ++ PE + + +
Sbjct: 571 EAKSPAE-VKSPEKAKSPAKEE--------AKSPAEAKSPEKAKSPVKEEAKSPAEAKSP 621
Query: 2252 VKEELSAVERLTQTSGQSTHTHKEPASGDEGIKVLKQRAK---KKPNPVEEE-------- 2300
VKEE + + + T +E S ++ K+ AK K +PV+ E
Sbjct: 622 VKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAK 681
Query: 2301 -PSRRRPRAPKEKAQPLEDLAGFTELSETSGHTQESLTAGKATKIPCESPPLEVVDTTAS 2359
P + ++P++ P+++ A E ++ S +E+ + KA +SP E T
Sbjct: 682 SPVKAEAKSPEKAKSPVKEEAKSPEKAK-SPVKEEAKSPEKA-----KSPVKEEAKTPEK 735
Query: 2360 TKRHLRTRVQKVQVKEEPSAVKFTQTSGETTDADKEPAGEDKGIKALKESAKQTPAPAAS 2419
K ++ + + + P K T + K PA E+ A K K +P
Sbjct: 736 AKSPVKEEAKSPEKAKSPEKAK---TLDVKSPEAKTPAKEEARSPADKFPEK-AKSPVKE 791
Query: 2420 VTGSRRRPRAP-RESAQAIE-DLAGFKDPAAGHTEESMTDDKTTKIPCKSSPELEDTATS 2477
S + ++P +E A+A E ++ ++ + EE + K P K + E + AT
Sbjct: 792 EVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPAT- 850
Query: 2478 SKRRPRTRAQKVEVKEELLAVGKLTQTSGETTHTDKEPVGEGKGTKAFKQPAKRKLDA-- 2535
P+T +K KEE +P E K A ++P + K++A
Sbjct: 851 ----PKTEEKKDSKKEE------------APKKEAPKPKVEEKKEPAVEKPKESKVEAKK 894
Query: 2536 EDVIGSRRQPRAPKEKAQPLEDLASFQELSQTPGHTEELANGAADSFTSAPKQTPDSGKP 2595
E+ ++ P KE +E + P E+A D + P K
Sbjct: 895 EEAEDKKKVPTPEKEAPAKVE-----VKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKE 949
Query: 2596 LKISRRVLRAPKVEPVGDVVSTRDPVKSQSKSNTSLPPLPFKRGGGKDGSVTGTKRLRCM 2655
++ + K + + T K K+ + P P K + S T K +
Sbjct: 950 AAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKP-KAEKAEKSSSTDQKDSK-- 1006
Query: 2656 PAPEEIVEELPASKK 2670
PE+ E+ A K
Sbjct: 1007 -PPEKATEDKAAKGK 1020
Score = 59.3 bits (142), Expect = 5e-08
Identities = 126/614 (20%), Positives = 226/614 (36%), Gaps = 74/614 (12%)
Query: 183 TPPVLKKIIKEQPQPSGKQESGSEIHVEVKAQSLVISPP---APSPR---KTPVASDQRR 236
T V ++ KE + GK+E G E + SPP A SP K+PV + +
Sbjct: 467 TEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKS 526
Query: 237 -RSCKTAPASSSKSQTEVPKRGGRKSGNLPSKRVSISRSQHDILQMICSKRRSGASEANL 295
K+ +KS EV KS P+K + S + ++ S A +
Sbjct: 527 PAEAKSPEKEEAKSPAEVKSPEKAKS---PAKEEAKSPPEAK-----SPEKEEAKSPAEV 578
Query: 296 IVAKSWADVVKLGAKQTQTKVIKHGPQRSMNKRQRRPATPKKPVGEVHSQFSTGHANSPC 355
+ K AK + + + + PA K PV E A SP
Sbjct: 579 KSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKE--------EAKSPA 630
Query: 356 TIIIGKAHTEKVHVPARPYRVLNNFISNQKMDFKEDLSGIAEMFKTPVKEQPQLTSTCHI 415
+ EK P + K KE+ E K+PVK + +
Sbjct: 631 EV----KSPEKAKSPTKEEA---KSPEKAKSPEKEEAKS-PEKAKSPVKAEAK------- 675
Query: 416 AISNSENLLGKQFQGTDSGEEPLLPTSESFGGNVFFSAQNAAKQPSDKCSASPPLRRQCI 475
+ +++ + + + + + P+ ++S AK P + + SP + +
Sbjct: 676 SPEKAKSPVKAEAKSPEKAKSPVKEEAKS---------PEKAKSPVKEEAKSPEKAKSPV 726
Query: 476 RENGNVAKTPRNTYKMTSLETKTSDTETEPSKTVSTANRSGRS-TEFRNIQKLPVESKSE 534
+E AKTP E K+ + P K + +S + T + + P + E
Sbjct: 727 KEE---AKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPE 783
Query: 535 ETNTEIVECILKRGQKATLLQQRREGEMKEIERPFETYKENIELKENDEKMKAMKRSRTW 594
+ + + E + + + L++ + KEI + E K ++ +E +++K + +
Sbjct: 784 KAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKK-EEVKSPVKEEEKPQEVKVKEPPKKA 842
Query: 595 GQKCAPMSDLTDLKSLPDTELMKDTARGQNLLQTQDHAKAPKSEKGKITKMPCQSLQPE- 653
++ AP + T+ K E + + + + K P EK K +K+ + + E
Sbjct: 843 EEEKAPATPKTEEKKDSKKE---EAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAED 899
Query: 654 PINTPTHTKQQLKASLGKVGVKEELLAVGKFTRTSGETTHTHREPAGDGKSIRTFKESPK 713
PT K+ + KV VKE+ E T ++ D K+ K + K
Sbjct: 900 KKKVPTPEKE----APAKVEVKED--------AKPKEKTEVAKKEPDDAKAKEPSKPAEK 947
Query: 714 QILDPAARVT---GMKKWPRTPKEEAQSLEDLAGFKELFQTPGPSEESMTDEKTTKIACK 770
+ P + T KK PK EA++ ED K L + P + ++ ++
Sbjct: 948 KEAAPEKKDTKEEKAKKPEEKPKTEAKAKED---DKTLSKEPSKPKAEKAEKSSSTDQKD 1004
Query: 771 SPPPESVDTPTSTK 784
S PPE + K
Sbjct: 1005 SKPPEKATEDKAAK 1018
Score = 39.7 bits (91), Expect = 0.044
Identities = 130/682 (19%), Positives = 236/682 (34%), Gaps = 108/682 (15%)
Query: 2250 KEVKEELSAVERLTQTSGQSTHTHKEPASGDEGIKVLKQRAKKKPNPVEEEPSRRRPRAP 2309
+EV+E AV RL GQ E E I ++QR + EE + R A
Sbjct: 148 REVREMRGAVLRLGAARGQ---LRLEQEHLLEDIAHVRQRLDDEARQREEAEAAARALAR 204
Query: 2310 ------------KEKAQPLEDLAGFT------ELSETSGHTQESLTAGKATKIPCESPPL 2351
++KAQ L++ G+ E+ E G Q S A +
Sbjct: 205 FAQEAEAARVDLQKKAQALQEECGYLRRHHQEEVGELLGQIQGSGAAQAQMQ-------- 256
Query: 2352 EVVDTTASTKRHLRTRVQKVQVKEEPSAVKFTQTSGETTDADKEPAGEDKGIKALKESAK 2411
+T + K + + +++++ + E AV+ T S E + E A K +
Sbjct: 257 --AETRDALKCDVTSALREIRAQLEGHAVQSTLQSEEWFRVRLDRLSE-----AAKVNTD 309
Query: 2412 QTPAPAASVTGSRRRPRAPRESAQAIEDLAGFKDPAAGHTEESMTDDKTTKIPC--KSSP 2469
+ +T RR+ +A +A++ + E+ D + +
Sbjct: 310 AMRSAQEEITEYRRQLQARTTELEALKSTKDSLERQRSELEDRHQADIASYQEAIQQLDA 369
Query: 2470 ELEDTATSSKRRPRTRAQKVEVKE----ELLAVGKLTQTSGETTHTDKEPVG----EG-- 2519
EL +T + R + VK E+ A KL + GE P+ EG
Sbjct: 370 ELRNTKWEMAAQLREYQDLLNVKMALDIEIAAYRKLLE--GEECRIGFGPIPFSLPEGLP 427
Query: 2520 -----------KGTKAFKQPAKRKLDAEDVIGSRRQPRAPKEKAQPLEDLASFQELSQTP 2568
K + K K + + V + + +E + E A +E +
Sbjct: 428 KIPSVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEE 487
Query: 2569 GHTEELANGAADSFTSAPKQTPDSGKPLKISRRVLRAPKVEPVGDVVSTRDPVKSQSKSN 2628
G EE A G + S P + ++ P K ++ +P E + P K ++KS
Sbjct: 488 GGEEEEAEGGEEETKSPPAE--EAASPEKEAK----SPVKEEAKSPAEAKSPEKEEAKSP 541
Query: 2629 TSLPPLPFKRGGGKDGSVTGTKRLRCMPAPEEIVEELPASKKQRVAPRARGKSSEPVVIM 2688
+ +PE+ + PA ++ + P A+ E
Sbjct: 542 AEVK------------------------SPEKA--KSPAKEEAKSPPEAKSPEKEEAK-S 574
Query: 2689 KRSLRTSAKRIEPAEELNSNDMKTNKEEHKLQDSVPENKGISLRSRRQNKTEAEQQITEV 2748
+++ K PA+E + + E K + V E ++ K EA+
Sbjct: 575 PAEVKSPEKAKSPAKEEAKSPAEAKSPE-KAKSPVKEEAKSPAEAKSPVKEEAKSPAEVK 633
Query: 2749 FVLAERIEINRNEKKPMKT-SPEMDIQNPDDGARKPIPRDKVTENKRCLRSARQNESSQP 2807
+ K P K SPE + + A+ P+ + + K + P
Sbjct: 634 SPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEK----------AKSP 683
Query: 2808 KVAEESGGQKSAKVLMQNQKGKGEAGNSDSMCLRSRKTKSQPAASTLESKSVQRVTRSVK 2867
AE +K+ + + K +A + +S + P E+K+ ++ VK
Sbjct: 684 VKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKE--EAKTPEKAKSPVK 741
Query: 2868 RCAENPKKAEDNVCVKKIRTRS 2889
A++P+KA+ K + +S
Sbjct: 742 EEAKSPEKAKSPEKAKTLDVKS 763
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 75.5 bits (184), Expect = 7e-13
Identities = 328/1587 (20%), Positives = 532/1587 (33%), Gaps = 271/1587 (17%)
Query: 1363 TKESMTNEKTTKVSYRASQPDLVDTPTSSKPQ-PKRSLRKADTEEEFLAFRKQTPSA--- 1418
T +S+++++ K+ SQP P Q P+ K + + A R QT A
Sbjct: 235 TPKSISSQQPEKIK---SQPPGTGKPIQGPTQTPQTDHAKLPLQRD--ASRPQTKQADIV 289
Query: 1419 -GKAMHTPKPAVGEEKDINTFLGTPVQKLDQPGNLPGSNRRLQTRKEKAQALEELTGFRE 1477
G+++ P+ + G P P PG + + LT +
Sbjct: 290 RGESVKPSLPSPSKPPIQQPTPGKP------PAQQPGHEKSQPGPAKPPAQPSGLT--KP 341
Query: 1478 LFQTPCTDNPTTDEKTTKKILCK--SPQSDPADTPTNTKQRPKRSLKKADVEEEFLAFRK 1535
L Q P T P T K + P PA + K ++ KA +
Sbjct: 342 LAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQP------- 394
Query: 1536 LTPSAGKAMHTPKAAVGEEKDINTFVGTPVEKLDLLG-----NLPGSKRRPQTPKEKAKA 1590
P GK TP G K VGTP G PG + P K
Sbjct: 395 --PGVGK---TPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKI 449
Query: 1591 LEDLAGFKELFQTPGHTEESMTDDKITEVSCKSP------QPDPVKTPTSSKQRLKISLG 1644
AG PG T T P QP P K P K
Sbjct: 450 PAQQAG-------PGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQ 502
Query: 1645 KVGVK----EEVLPVGKLTQTSGKTTQTHRETAGDGKSIKA---FKESAKQMLDPANY-G 1696
+ G ++ P Q G T ++ S + K SA+Q P + G
Sbjct: 503 QPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTG 562
Query: 1697 TGMERWPRTPKEEAQSLEDLAGFKELFQTPDHTEESTTDD--KTTKIACKSPPPESMDTP 1754
+G P T A+ Q P T TT++ P + +T
Sbjct: 563 SGKPLQPPTVSPSAK------------QPPSQGLPKTICPLCNTTELLLHVPEKANFNTC 610
Query: 1755 TSTRRRPKTPLGKR------DIVEELSALKQLTQTTHTDKVPGDEDKGINVFRETAKQKL 1808
T + + G ++ E L Q+ + D P + +TA
Sbjct: 611 TECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKL--KTAPVTT 668
Query: 1809 DPAASVTGSKRQPRTPKGKAQPLEDLAGLKELFQTPICTDKPTTHEKTTKIACRSPQPDP 1868
A S + + Q +PK A P +DL+ E + P +PT H + A + P+ D
Sbjct: 669 TSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADS 728
Query: 1869 VGTPTIFKPQSKRSLR-KADVEEES----LALRKRTPSVGKAMDTPKP--AGGDEKDMKA 1921
+ P K S S + KA V ++ ++ T V + T KP +
Sbjct: 729 LSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAE 788
Query: 1922 FMGTPVQKLDLPGNLPGSKRWPQTPKE----KAQALEDLAGFKELFQTPGTDKPTTDEKT 1977
TP K D + S+ +P T ++ ++A+ A ++ PG P+++ K
Sbjct: 789 EKTTPPLKTD---SAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPG---PSSESKG 842
Query: 1978 TKIACKSPQPDPVDTPASTKQRPKRNLRKADVEEEFLALRKRT-------PSAGKAMDTP 2030
K Q DPV K+ PK+ K + + + K + P+AG+ + TP
Sbjct: 843 QK------QVDPV----QKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTP 892
Query: 2031 KPAVSDEKNINTFVETPVQKLDLLGNLPGSKRQPQTPKEKAEALEDLVGFKELFQTPGHT 2090
+ + ++ F L+L K QP TP+E L GF G +
Sbjct: 893 QQSPKPQEQSRRF------SLNLGSITDAPKSQPTTPQETVTG--KLFGF-------GAS 937
Query: 2091 EESMTDDKITEVSCKSPQPESFKTSRSSKQRLKIPLVKVDMKEEPLAVSKLTRTSGETTQ 2150
S + I+ P +S + MK+ P A S+ + G
Sbjct: 938 IFSQASNLISTAGQPGPHSQSGPGA--------------PMKQAP-APSQPPTSQGPPKS 982
Query: 2151 THTEPTGDSKSIKAFKES---PKQILDPAASVTGSRRQLRTRKEKARALEDLVDFKELFS 2207
T P +KSI KE+ + L+P A + ++ T K+ + D K L +
Sbjct: 983 TGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKP----PPIKDSKSLTA 1038
Query: 2208 APGHTEESMTIDKNTK-------------IPCKSPPPELTDTATSTKRC-----PKTRPR 2249
P ++K+ K I K PP T T + C T
Sbjct: 1039 EPQKAVLPTKLEKSPKPESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHL 1098
Query: 2250 KEVKEELSA-VERLTQTSGQSTHTHKEPASGDEGIKVLKQRAKKKPNPVEEEPSRRRPRA 2308
E++E L + SGQ K P + K P PV E S ++
Sbjct: 1099 TEIQEWLCLNCQTQRAISGQLGDIRKMPPA--------PSGPKASPMPVPTESSSQKTAV 1150
Query: 2309 PKEKAQPLEDLAGFTELSETSGHTQESLTAGKATKIPCESPPLEVVDTTASTKRHLRTRV 2368
P P L E + + L K T + PP+ D + + +
Sbjct: 1151 P-----PQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLEKDKA 1205
Query: 2369 QKVQVKEE--------PSAVKFTQTSGETTDADKEPAGEDKGIKALKESAKQTPAP---- 2416
+Q K+ P K + +K+P EDK K L E+ P
Sbjct: 1206 SALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDK--KLLPEAKTSAPEEQKHD 1263
Query: 2417 --------AASVTGSRRRPRAPRESAQAIEDLAGFKDPAAGHTEESMTDDKTTKIPCKSS 2468
A R P+ +E Q + G P+ DDKTTK K
Sbjct: 1264 LLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGL--PSGTPQSLPKEDDKTTK-TIKEQ 1320
Query: 2469 PELEDTATSSKRRPRTRAQKVEVKEELLAVGKLTQTSGETTHTDKEPVGEGKGTKAFKQP 2528
P+ TA + P +K E +++ Q +D +G + + P
Sbjct: 1321 PQPPCTAKPDQVEP--GKEKTEKEDDKSDTSSSQQPKSPQGLSDTGYSSDGISSSLGEIP 1378
Query: 2529 AKRKLDAEDVI-GSRRQPRAPKEKAQPLEDLASFQE--LSQTPGHTEELANGAADSFTS- 2584
+ D +D++ G ++ + + DLA + LS LA+ ++ T
Sbjct: 1379 SLIPTDEKDILKGLKKDSFSQESSPSSPSDLAKLESTVLSILEAQASTLADEKSEKKTQP 1438
Query: 2585 ---APKQTPDSGKPLKISRRVLRAPKVEPVGDVVSTRDPVKSQSKSNTSLPPLPFKRGGG 2641
+P+Q D K +S E + +S + +SQ + + FK+
Sbjct: 1439 HEVSPEQPKDQEKTQSLS---------ETLEITISEEEIKESQEERKDT-----FKKDSQ 1484
Query: 2642 KDGSVTGTKRLRCMPAPEEIVEELPASKKQRVAPRARGKSSEPVVIMKRSLRTSAKRIEP 2701
+D + +K + E V+++ ++++ SE + +R RTS
Sbjct: 1485 QD--IPSSKDHK---EKSEFVDDI-TTRREPYDSVEESSESENSPVPQRKRRTSVG---- 1534
Query: 2702 AEELNSNDMKTNKEEHKLQDSVPENKGISLRSRRQNKTEAEQQITEVFVLAERIEINRNE 2761
++ +E+K +DS +G K E E +E E RN+
Sbjct: 1535 ---------SSSSDEYKQEDS----QGSGEEEDFIRKQIIEMSADEDASGSEDDEFIRNQ 1581
Query: 2762 KKPMKTSPEMDIQNPDDGARKPIPRDKVTENKRCLRSARQNESSQPKVAEESGGQKSAKV 2821
K + +S E + G + K+T K R S + E++G + S
Sbjct: 1582 LKEISSSTESQKKEETKG------KGKITAGKH----RRLTRKSSTSIDEDAGRRHS--- 1628
Query: 2822 LMQNQKGKGEAGNSDSMCLRSRKTKSQ 2848
+ + +S L+ R+TKSQ
Sbjct: 1629 ----WHDEDDEAFDESPELKYRETKSQ 1651
Score = 73.2 bits (178), Expect = 4e-12
Identities = 381/1976 (19%), Positives = 666/1976 (33%), Gaps = 287/1976 (14%)
Query: 845 PGSKRQLQTPKEKAQALEDLAGFKELFQTPGHTEELVAAGKTTKIPCDSPQSDPVDTPTS 904
PG+ + +Q P + Q + P + + G++ K SP P+ PT
Sbjct: 252 PGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTP 311
Query: 905 TKQRPKRSIRKADVEGELLACRNLMPSAGKAMHTPKPSVGEEKDIIIFVGT---PVQKLD 961
K ++ + G A +PS G K + GT PVQ
Sbjct: 312 GKPPAQQPGHEKS-------------QPGPAKPPAQPS-GLTKPLAQQPGTVKPPVQPPG 357
Query: 962 LTE---NLTGSKRRPQTPKEEAQALEDLTGFKELFQTPGHTEEAVAAGKT-TKMPCESSP 1017
T+ G + P + + G K L Q PG GKT + P + P
Sbjct: 358 TTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPG-------VGKTPAQQPGPAKP 410
Query: 1018 P-ESADTPTSTRRQP------------KTPLEKRDVQK----ELSALKKLTQTSGETTHT 1060
P + TP +QP KTP+++ K + K Q +G T
Sbjct: 411 PTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPP 470
Query: 1061 DKVPGGEDKSINAFRETAKQKLDPAASVTGSKRHPKTKEKAQPLEDLAGLKELFQTPVCT 1120
++PG P ++ S++ TK P + K Q P T
Sbjct: 471 SQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKP---PPQQPGPAKPSPQQPGST 527
Query: 1121 DKPTTHEKTTKIACRSQPDPV--DTPTSSKPQSKRSLRKVDVEEEFFALRKRTPSAGKA- 1177
P+ + K + + QP P S+KP S+ K K+ PS G
Sbjct: 528 KPPSQQPGSAKPSAQ-QPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPK 586
Query: 1178 ------------MHTPKPAVSGEKNIYAFMGTPVQKL---DLTENLTGSKRRLQTPKEKA 1222
+H P+ A N T V L + +LT K L +
Sbjct: 587 TICPLCNTTELLLHVPEKA---NFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMK 643
Query: 1223 QALE-DLAGFKELFQTRGHTEESMTNDKTAKVACKSSQPDPDKNPASSKRRLK------- 1274
+AL DLA Q + T T +K + + Q P K+ A + K
Sbjct: 644 RALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKP 703
Query: 1275 -------------TSLGKVGVKEELLAVGKLTQTSGETTHTHTEPTGDGKSMKAFMESPK 1321
++ K + + L+ + + P D K + M P
Sbjct: 704 PPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPT 763
Query: 1322 QILDSAASLTGSKRQLRTPKGKSEVPEDLAGFIELFQTPSHTKESMTNEKTTKVSYRASQ 1381
L S++S T +K + + K +S+ E ++ T EK + +A
Sbjct: 764 TDLVSSSSAT-TKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIP 822
Query: 1382 PDLVDTPTSSKPQPKRSLRKADTEEEFLAFRKQTPSAGKAMHTPKPAVGEEKDINTFLGT 1441
D+ S P P S K + + + +K+ P + +PKP + K + T
Sbjct: 823 RPASDSKIISHPGPS-SESKGQKQVDPVQ-KKEEPKKAQTKMSPKP---DAKPMPKGSPT 877
Query: 1442 PVQKLDQPGNLPGSNRRLQTRKEKAQALEELTGFR----ELFQTPCTDNPTTDEKTTKKI 1497
P PG P + + + T ++ + E+ F + P + T E T K+
Sbjct: 878 P------PGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKL 931
Query: 1498 L---------CKSPQSDPADTPTNTKQRPKRSLKKADVEEEFLAFRKLTPSAGKAMHTPK 1548
+ S +++ P +K+A + + S G+A P
Sbjct: 932 FGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPA 991
Query: 1549 AAVGEEKDINTFVGTPVEKLDLLGNLPGSKRRPQTPKEKA--KALEDLAGFKELFQTPGH 1606
++ +K+ EKL+ + +R +T K+ K + L + P
Sbjct: 992 KSIPVKKETKA---PAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTK 1048
Query: 1607 TEESMTDDKI-----TEVSCKSPQPDPVKTPTSSKQRLKISLGKVGVKEEVLPVGKLTQT 1661
E+S + TE++ S P T T K ++ G P LT+
Sbjct: 1049 LEKSPKPESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCG-------FNPTPHLTEI 1101
Query: 1662 SG---KTTQTHRETAGDGKSIKAFKES-----AKQMLDPANYGTGMERWP---RTPKEEA 1710
QT R +G I+ + A M P + P + K++
Sbjct: 1102 QEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVPTESSSQKTAVPPQVKLVKKQE 1161
Query: 1711 QSLED------LAGFKELFQTPDHTEESTTDDKTTKIACKSPPPESMDTPTSTRRRPKTP 1764
Q ++ L KE TTD K + + D ++ + + P
Sbjct: 1162 QEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLEK------DKASALQEKKPLP 1215
Query: 1765 LGKRDIVEELSALKQLTQTTHTDKVPGDEDKGINVFRETA----------KQKLDPAASV 1814
K+ I EE + + +K P EDK + +T+ K ++ A
Sbjct: 1216 EEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEK 1275
Query: 1815 TGSKRQPRTPKGKAQPLEDLAGLKELFQTPICTDKPTTHEKTTKIACRSPQPDPVGTPTI 1874
+ P+T + QP + GL TP P +KTTK PQP P
Sbjct: 1276 LEGRVAPKTVQEGKQPQTKMEGLPS--GTP--QSLPKEDDKTTKTIKEQPQPPCTAKPDQ 1331
Query: 1875 FKPQSKRSLRKADVEEESLALRKRTPSVGKAMDTPKPAGGDEKDMKAFMGT-PVQKLDLP 1933
+P +++ ++ D + S + + ++P DT + G + P + D+
Sbjct: 1332 VEPGKEKTEKEDDKSDTSSSQQPKSPQ--GLSDTGYSSDGISSSLGEIPSLIPTDEKDIL 1389
Query: 1934 GNLP----GSKRWPQTPKEKAQALEDLAGFKELFQTPGTDKPTTDEKTTKIACKSPQPDP 1989
L + P +P + A+ + E + D+ + ++KT QP
Sbjct: 1390 KGLKKDSFSQESSPSSPSDLAKLESTVLSILEAQASTLADEKS-EKKTQPHEVSPEQPKD 1448
Query: 1990 VDTPASTKQRPKRNLRKADVEEEFLALRKRTPSAGKAMDTPKPAVSDEKNINTFVETPVQ 2049
+ S + + + + +++E + +R + K P+ D K + FV+
Sbjct: 1449 QEKTQSLSETLEITISEEEIKE---SQEERKDTFKKDSQQDIPSSKDHKEKSEFVDDITT 1505
Query: 2050 KLDLLGNLPGSKRQ-----PQTPKEKAEALEDLVGFKELFQTPGHTEESMTDDKITEVSC 2104
+ + ++ S PQ + + +K+ EE +I E+S
Sbjct: 1506 RREPYDSVEESSESENSPVPQRKRRTSVGSSSSDEYKQEDSQGSGEEEDFIRKQIIEMSA 1565
Query: 2105 KSPQPESFKTSRSSKQRLKIPL-VKVDMKEEPLAVSKLT-----RTSGETTQTHTEPTGD 2158
S Q +I + KEE K+T R + +++ + E G
Sbjct: 1566 DEDASGSEDDEFIRNQLKEISSSTESQKKEETKGKGKITAGKHRRLTRKSSTSIDEDAGR 1625
Query: 2159 SKSI-----KAFKESPKQILDPAAS-------VTGSR--RQLRT--------------RK 2190
S +AF ESP+ S VTG R+ +T
Sbjct: 1626 RHSWHDEDDEAFDESPELKYRETKSQESEELVVTGGGGLRRFKTIELNSTIADKYSAESS 1685
Query: 2191 EKARAL----EDLVDFKELFSAP---GHTEESMTIDKNTKIPCKSPPP-----ELTDTAT 2238
+K +L E ++ + L +P E S ++ ++ P SP E +D++
Sbjct: 1686 QKKTSLYFDEEPELEMESLTDSPEDRSRGEGSSSLHASSFTPGTSPTSVSSLDEDSDSSP 1745
Query: 2239 STKRCPKTRPRKE----------VKEELSAVERLTQTSGQSTHTHKEPASGDEGIKVLKQ 2288
S K+ + RK E+ S E L + K+ + K +
Sbjct: 1746 SHKKGESKQQRKARHRPHGPLLPTIEDSSEEEELREEEELLKEQEKQREIEQQQRKSSSK 1805
Query: 2289 RAKKKPNPVEEEPSRRRPRAPKEKAQPLEDLAGFTELSETSGHTQESLTAGKATKIPCES 2348
++KK + + + R RP+ P P+ED + EL + + E L ++ S
Sbjct: 1806 KSKKDKDELRAQRRRERPKTPPSNLSPIEDASPTEELRQAA--EMEELHRSSCSEY---S 1860
Query: 2349 PPLEVVDTTASTKRHLRTRVQKVQVKEEPSAVKFTQTSGETTDADKEPAGEDKGIKALKE 2408
P +E VQKV + P+AV + E + KE G K +K+ +E
Sbjct: 1861 PSIESDPEGFEISPEKIIEVQKVY--KLPTAVSLYSPTDEQSIMQKE--GSQKALKSAEE 1916
Query: 2409 SAKQTPAPAASVTGSRRRPRAPRESAQAIEDLAGFKDPAAG------HTEESMTDDKTTK 2462
++ T + A E + E K+P G + ES+ +D T
Sbjct: 1917 MYEE----MMHKTHKYKAFPAANERDEVFE-----KEPLYGGMLIEDYIYESLVED-TYN 1966
Query: 2463 IPCKSSPELEDTATSSKRRPRTRAQKVEVKEELL--AVGKLTQTSGETTHTD---KEPVG 2517
S + + + R QK+ + E++ + K+T E +
Sbjct: 1967 GSVDGSLLTRQEEENGFMQQKGREQKIRLSEQIYEDPMQKITDLQKEFYELESLHSVVPQ 2026
Query: 2518 EGKGTKAFKQPAKRKL-DAEDVIGSRRQPRAPKEKAQPLEDLASFQELSQTPGHTEELAN 2576
E + +F P ++ D ++ S + R + E+L Q++ TPG
Sbjct: 2027 EDIVSSSFIIPESHEIVDLGTMVTSTEEERKLLDADAAYEELMKRQQMQLTPG------- 2079
Query: 2577 GAADSFTSAPKQTPDSGKPLKISRRVLRAPKVEPVGDVVSTRDPVKSQSKSNTSLP 2632
S+P Q P + + R P V+S S S + S+P
Sbjct: 2080 -------SSPTQAPIGEDMTESTMDFDRMPDASLTSSVLSGASLTDSTSSATLSIP 2128
Score = 60.8 bits (146), Expect = 2e-08
Identities = 297/1426 (20%), Positives = 471/1426 (33%), Gaps = 270/1426 (18%)
Query: 1500 KSPQSDPADTPTNTKQRPKRSLKKADVEEEFLAFRKLTPSAGKAMHTPKAAVGEEKDINT 1559
+S Q P +P+ + +S + D++EE H G ++N
Sbjct: 120 RSEQKLPGRSPSTISLKESKS--RTDLKEE---------------HKSSMMPGFLSEVNA 162
Query: 1560 F--VGTPVEKLDLLGNLPGSKRRPQTPKEKAKALEDLAGFKELFQTPGHTEESMTDDKIT 1617
V + V K + + S+ + +K K ++ G E P ++
Sbjct: 163 LSAVSSVVNKFNPFDLISDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQ 222
Query: 1618 EVSCKSP-QPDPVKTPTSSKQRLKISLGKVGVKEEVLPVGKLTQTSGKTTQTHRETAGDG 1676
+ + P Q D SS+Q KI K + GK Q +T QT D
Sbjct: 223 QGPGRDPLQQDGTPKSISSQQPEKI-------KSQPPGTGKPIQGPTQTPQT------DH 269
Query: 1677 KSIKAFKESAKQMLDPANYGTGMERWPRTPKEEAQSLEDLAGFKELFQTPDHTEESTTDD 1736
+ +++++ A+ G P P ++ K Q P H +
Sbjct: 270 AKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPA 329
Query: 1737 KT-------TKIACKSP----PPESMDTPTSTRRRPKTPLGKRDIVEELSALKQLTQTTH 1785
K TK + P PP P T + P PLG K Q T
Sbjct: 330 KPPAQPSGLTKPLAQQPGTVKPPVQ---PPGTTKPPAQPLGPA---------KPPAQQTG 377
Query: 1786 TDKVPGDEDKGINVFRETAKQKLDPAASVTGSKRQPRTPKGKAQPLEDLAGLKELFQTPI 1845
++K P E G + PA G + P G +PL GL+ + P
Sbjct: 378 SEK-PSSEQPGPKALAQPPGVGKTPAQQ-PGPAKPPTQQVGTPKPLAQQPGLQSPAKAPG 435
Query: 1846 CTDKPTTHEKTTKIACRSPQPDPVGT----PTIFKPQSKRSLRKADVEEESLALRKRTPS 1901
T P KI + P PT KP S+ A + K P
Sbjct: 436 PTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPT--KPPSQLP-GPAKPPPQQPGPAKPPPQ 492
Query: 1902 VGKAMDTPKPAGGDEKDMKAFMGTPVQKLDLPGNLPG-SKRWPQTPKEKAQALEDLAGFK 1960
+ P G K P PG +K PQ P + K
Sbjct: 493 QPGSAKPPSQQPGSTKP--------------PPQQPGPAKPSPQQPGSTKPPSQQPGSAK 538
Query: 1961 ELFQTPGTDKPTTDEKTTKIA---CKSPQPDPVDTPASTKQRPKRNLRKADVEEEFLALR 2017
Q P KP+ + T ++ P P +P S KQ P + L K +
Sbjct: 539 PSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSP-SAKQPPSQGLPK--------TIC 589
Query: 2018 KRTPSAGKAMDTPKPAVSDEKNINTFVETPVQKLDLLGNLPGSKRQPQTPKEK------A 2071
+ + P+ A N NT E L G P P + K
Sbjct: 590 PLCNTTELLLHVPEKA-----NFNTCTECQTTVCSLCGFNP----NPHLTEVKEWLCLNC 640
Query: 2072 EALEDLVGFKELFQTPGHTEESMTDDKIT---EVSCKSPQPE--SFKTSRSSKQRL-KIP 2125
+ L G +L P + + +T VS SPQP+ S K + KQ L K P
Sbjct: 641 QMKRALGG--DLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAP 698
Query: 2126 LVKVDMKEEPLAVSKLTRTSGETTQTHTEPTGDSKSIKAFKESPKQILDPAASVTGSRRQ 2185
+ K+ P V + T + + P DS S A PK+ P+
Sbjct: 699 ----EPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPA---PPKEPSVPSEQDKAPVAD 751
Query: 2186 LRTRKEK-ARALEDLVDFKELFSAPGHTEESMTIDKNTKIPCKSPPPELTDTATSTKRCP 2244
+ ++ K + DLV + P + ++ K+ PP TD+A ++ P
Sbjct: 752 DKPKQPKMVKPTTDLVSSSSATTKPDIPSSKV----QSQAEEKTTPPLKTDSAKPSQSFP 807
Query: 2245 KTRPRKEVKEELSAVERLTQTSGQSTHTHKEPASGDEGIKVLKQRAKKKPNPVEEEPSRR 2304
T K + A+ R S +H P+S +G +K+ +PV++ +
Sbjct: 808 PT-GEKVSPFDSKAIPR--PASDSKIISHPGPSSESKG--------QKQVDPVQK---KE 853
Query: 2305 RPRAPKEKAQPLEDLAGFTELSETSGHTQESLTAGKATKIPCESPPLEVVDTTASTKRHL 2364
P+ + K P D + S T + TAG+ P +SP
Sbjct: 854 EPKKAQTKMSPKPDAKPMPKGSPTPPGPRP--TAGQTVPTPQQSP--------------- 896
Query: 2365 RTRVQKVQVKEEPSAVKFTQTSGETTDADKEP--------AGEDKGIKALKESAKQTPAP 2416
K + + +F+ G TDA K G+ G A S
Sbjct: 897 ---------KPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLIS 947
Query: 2417 AASVTG--SRRRPRAPRESAQAIEDLAGFKDPAAGHTEESMTDDKTT----KIPCKSSPE 2470
A G S+ P AP + A PA S K+T P KS P
Sbjct: 948 TAGQPGPHSQSGPGAPMKQA-----------PAPSQPPTSQGPPKSTGQAPPAPAKSIPV 996
Query: 2471 LEDTATSSKRRPRTRAQKVEVKEELLAVGKLTQTS------GETTHTDKEPVGEGKGTKA 2524
++T + A+K+E K E K T+T ++ EP TK
Sbjct: 997 KKETKAPA-------AEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKL 1049
Query: 2525 FKQPAKRK----LDAEDVIGSRRQPR---APKEKAQ--------PLEDLASFQELSQTPG 2569
K P E IGS+ P + K Q P L QE
Sbjct: 1050 EKSPKPESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNC 1109
Query: 2570 HTEELANGAADSFTSAPKQTPDSGKPLKISRRVLRAPKVEPVGDVVSTRDPVKSQSKSNT 2629
T+ +G P PK P+ PV ++S S
Sbjct: 1110 QTQRAISGQLGDIRKMPPAP--------------SGPKASPM--------PVPTESSSQK 1147
Query: 2630 SLPPLPFKRGGGKDGSV-TGTKRLRCMPAPEEI-VEELP----ASKKQRVAPRARGKSSE 2683
+ P K ++ V T +++ E + +E++P +KQ + + K+S
Sbjct: 1148 TAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLEKDKAS- 1206
Query: 2684 PVVIMKRSLRTSAKRIEPAEELNSNDMKTNKEEHKLQDSVPENKGISLRSRRQNKTEAEQ 2743
+ K+ L K I E++ S + K EE K PE+K + ++ E +
Sbjct: 1207 -ALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKK---PTPEDKKLLPEAKTSAPEEQKH 1262
Query: 2744 QI--TEVFVLAERIEINRNEKKPMK--TSPEMDIQNPDDGARKPIPR--DKVTENKR--- 2794
+ ++V + E++E R K ++ P+ ++ G + +P+ DK T+ +
Sbjct: 1263 DLLKSQVQIAEEKLE-GRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQP 1321
Query: 2795 ---CLRSARQNESSQPKVAEESGGQKSAKVLMQNQKGKGEAGNSDS 2837
C Q E + K +E ++ +Q+ K G SD+
Sbjct: 1322 QPPCTAKPDQVEPGKEKTEKEDDKSDTS----SSQQPKSPQGLSDT 1363
Score = 52.4 bits (124), Expect = 7e-06
Identities = 272/1367 (19%), Positives = 472/1367 (34%), Gaps = 252/1367 (18%)
Query: 597 KCAPMSDLTDL-KSLPD---TELMKDTARGQNLLQTQDHAKAPK-----------SEKGK 641
K AP++ + + KS P T KD A Q+L + + K P S K K
Sbjct: 662 KTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAK 721
Query: 642 ITKMPCQSLQPEPINTPTHTKQQLKASLGKVGVKEELLAVGKFTRTSGETTHTHRE-PAG 700
+P P P+ +Q KA + K+ + S + T + P+
Sbjct: 722 QPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSS 781
Query: 701 DGKSIRTFKESPKQILDPAARVTGMKKWPRTPKE----EAQSLEDLAGFKELFQTPGPSE 756
+S K +P D A + +P T ++ +++++ A ++ PGPS
Sbjct: 782 KVQSQAEEKTTPPLKTDSAKP---SQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSS 838
Query: 757 ESMTDEKTTKIACKSPPPESVDTPTSTKQWPKRSLRKADVEEEFLALRKLTPSAGKAMLT 816
ES ++ + K P ++ TK PK + + + P+AG+ + T
Sbjct: 839 ESKGQKQVDPVQKKEEPKKA-----QTKMSPKPDAK--PMPKGSPTPPGPRPTAGQTVPT 891
Query: 817 PKPAGGDEKDIKAFMGTPVQKLDLAGTLPGSKRQLQTPKEKAQALEDLAGF--------K 868
P+ + ++ + F L+L K Q TP+E L GF
Sbjct: 892 PQQSPKPQEQSRRF------SLNLGSITDAPKSQPTTPQETVTG--KLFGFGASIFSQAS 943
Query: 869 ELFQT---PGHTEELVAAGKTTKIPCDSPQSDPVDTPTSTKQRPKRSIRKADVEGELL-- 923
L T PG + + P S P ST Q P + V+ E
Sbjct: 944 NLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAP 1003
Query: 924 ACRNLMPSAGKAMHTPK-------PSVGEEKDII-----IFVGTPVQK---------LDL 962
A L P A +A + P + + K + + T ++K L
Sbjct: 1004 AAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCK 1063
Query: 963 TENLTGSKRRP--QTPKEEAQALEDLTGF---------KELFQTPGHTEEAVAA--GKTT 1009
TE GSK P T E + +L GF +E T+ A++ G
Sbjct: 1064 TELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIR 1123
Query: 1010 KMPCESSPPESADTPTSTRRQ-------PKTPLEKRDVQK-ELSALKKLTQTSGETTHTD 1061
KMP S P+++ P T P+ L K+ Q+ + A K + + ET +
Sbjct: 1124 KMPPAPSGPKASPMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSME 1183
Query: 1062 KVPGGEDKSINAFRETAKQKLDPAASVTGSKRHPKTKEKAQPLEDLAGLKELFQTPVCTD 1121
K+P + + +E +K + D A+++ K P+ K K P E+ +E + P+ +
Sbjct: 1184 KIP--PMVTTDQKQEESKLEKDKASALQEKKPLPEEK-KLIPEEEKIRSEE--KKPLLEE 1238
Query: 1122 KPTTHEKTTKIACRSQPDPVDTPTSSKPQSKRSLRKVDVEEEFFALRKRTPSAGKAMHTP 1181
K T E + + TS+ + K L K V+ L R P
Sbjct: 1239 KKPTPEDKKLLP--------EAKTSAPEEQKHDLLKSQVQIAEEKLEGRV--------AP 1282
Query: 1182 KPAVSGEKNIYAFMGTPVQKLDLTENLTGSKRRLQTPKEKAQALEDLAGFKELFQTRGHT 1241
K G++ G P +G+ + L PKE
Sbjct: 1283 KTVQEGKQPQTKMEGLP----------SGTPQSL--PKE--------------------- 1309
Query: 1242 EESMTNDKTAKVACKSSQPDPDKNPASSKRRLKTSLGKVGVKEELLAVGKLTQTSGETTH 1301
+DKT K + QP P +++ K +++ Q
Sbjct: 1310 -----DDKTTKTIKEQPQPPCTAKP----DQVEPGKEKTEKEDDKSDTSSSQQPKSPQGL 1360
Query: 1302 THTEPTGDGKSMKAFMESPKQI-LDSAASLTGSKRQLRTPKGKSEVPEDLAGFIELFQTP 1360
+ T + DG S + E P I D L G K+ + + P DLA
Sbjct: 1361 SDTGYSSDGIS-SSLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSPSDLAKL------- 1412
Query: 1361 SHTKESMTNEKTTKVSYRASQPDLVDTPTSSKPQPKRSLRKADTEEEFLAFRKQTPSAGK 1420
E T A L D + K QP + ++E +T
Sbjct: 1413 ---------ESTVLSILEAQASTLADEKSEKKTQPHEVSPEQPKDQEKTQSLSETLEITI 1463
Query: 1421 AMHTPKPAVGEEKDINTFLGTPVQKLDQPGNLPGSNRRLQTRKEKAQALEELTGFRELFQ 1480
+ K + E KD TF K D ++P S + KEK++ ++++T RE +
Sbjct: 1464 SEEEIKESQEERKD--TF------KKDSQQDIPSS----KDHKEKSEFVDDITTRREPYD 1511
Query: 1481 TPCTDNPTTDEKTTKKILCKSPQSDPADTPTNTKQRPKRSLKKADVEEEFLAFRKLTPSA 1540
+ + + + ++ S S +D + + + + EE+F+ + + SA
Sbjct: 1512 SVEESSESENSPVPQRKRRTSVGSSSSD------EYKQEDSQGSGEEEDFIRKQIIEMSA 1565
Query: 1541 ---GKAMHTPKAAVGEEKDINTFV-GTPVEKLDLLGNLPGSKRRPQTPKEKAKALEDLAG 1596
+ + K+I++ E+ G + K R T K ED AG
Sbjct: 1566 DEDASGSEDDEFIRNQLKEISSSTESQKKEETKGKGKITAGKHRRLTRKSSTSIDED-AG 1624
Query: 1597 FKELFQTPGHTEESMTDDKITEVSCKSPQPDPVKTPTSSKQRLKISLGKVGVKEEVLPVG 1656
+ + H E+ D+ E+ + T S++ EE++ G
Sbjct: 1625 RRHSW----HDEDDEAFDESPELKYRE---------TKSQE-----------SEELVVTG 1660
Query: 1657 KLTQTSGKTTQTHRETAGDGKSIKAFKESAKQMLDPANYGTGMERWPRTPKEEAQSLEDL 1716
KT + + T D S ++ ++ D P+ E +SL D
Sbjct: 1661 GGGLRRFKTIELN-STIADKYSAESSQKKTSLYFD------------EEPELEMESLTDS 1707
Query: 1717 AGFKELFQTPDHTEESTTDDKTTKIACKSPPPESMDTPT----------STRRRPKTPLG 1766
+ + S+ T+ + S +S +P+ R RP PL
Sbjct: 1708 PEDRSRGEGSSSLHASSFTPGTSPTSVSSLDEDSDSSPSHKKGESKQQRKARHRPHGPL- 1766
Query: 1767 KRDIVEELSALKQLTQTTHTDKVPGDEDKGINVFRETAKQKLDPAASVTGSKR---QPRT 1823
+E+ S ++L + K + + R+++ +K ++R +P+T
Sbjct: 1767 -LPTIEDSSEEEELREEEELLKEQEKQREIEQQQRKSSSKKSKKDKDELRAQRRRERPKT 1825
Query: 1824 PKGKAQPLEDLAGLKELFQTPICTDKPTTHEKTTKIACRSPQPDPVG 1870
P P+ED + +EL Q + H + S + DP G
Sbjct: 1826 PPSNLSPIEDASPTEELRQ---AAEMEELHRSSCSEYSPSIESDPEG 1869
Score = 38.9 bits (89), Expect = 0.075
Identities = 93/467 (19%), Positives = 160/467 (34%), Gaps = 60/467 (12%)
Query: 2217 TIDKNTKIPCKSPPPELTDTATSTKRCPKTRPRKEVKEE---------------LSAVER 2261
T K+P +SP ST +++ R ++KEE LSAV
Sbjct: 118 TFRSEQKLPGRSP---------STISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSS 168
Query: 2262 LTQTSGQSTHTHKEPASGDEGIKVLK--QRAKKKPNPVEEEPSRRRPRAPKEKAQPLEDL 2319
+ AS +E K K Q+ + KP + + P +++P P K Q
Sbjct: 169 VVNKFNPFDLISDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQG---- 224
Query: 2320 AGFTELSETSGHTQESLTAGKATKIPCESP----PLEVVDTTAST---KRHLRTRVQKVQ 2372
G L + T +S+++ + KI + P P++ T T K L+ + Q
Sbjct: 225 PGRDPLQQDG--TPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQ 282
Query: 2373 VKE---------EPSAVKFTQTSGETTDADKEPAGEDKGIKALKESAKQTPAPAASVTGS 2423
K+ +PS ++ + K PA + K+ AK P+
Sbjct: 283 TKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPL 342
Query: 2424 RRRP-------RAPRESAQAIEDLAGFKDPAAGHTEESMTDDKTTKIPCKSSPELEDTAT 2476
++P + P + + L K PA E + ++ P + T
Sbjct: 343 AQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPA 402
Query: 2477 SSKRRPRTRAQKVEVKEELLAVGKLTQTSGETTHTDKEPVGE-GKGTKAFKQPAKRKLDA 2535
+ Q+V + L L Q+ + K PV + G G +Q K A
Sbjct: 403 QQPGPAKPPTQQVGTPKPLAQQPGL-QSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSA 461
Query: 2536 EDVIGSRRQPRAPKEKAQPLEDLASFQELSQTPGHTEELANGAADSFTSAPKQTPDSGKP 2595
+ ++ + P P + + Q PG + + T P Q P KP
Sbjct: 462 QQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGS--TKPPPQQPGPAKP 519
Query: 2596 LKISRRVLRAPKVEPVGDVVSTRDPVKSQSKSNTSLPPLPFKRGGGK 2642
+ P +P S + P ++ + S P+ + G GK
Sbjct: 520 SPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVS-QTGSGK 565
Score = 33.9 bits (76), Expect = 2.4
Identities = 171/859 (19%), Positives = 281/859 (32%), Gaps = 85/859 (9%)
Query: 1991 DTPASTKQRPKRNLRKADVEEEFLALRKRTPSAGKAMDTPKPAVSDEKNINTFVETPVQK 2050
DT S ++ P R+ ++E + RT + + P E N + V + V K
Sbjct: 117 DTFRSEQKLPGRSPSTISLKES----KSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNK 172
Query: 2051 LDLLGNLPGSKRQPQTPKEKAEALEDLVGFKELFQTPGHTEESMTDDKITEVSCKSP-QP 2109
+ + S+ + +K + ++ G E P ++ + + P Q
Sbjct: 173 FNPFDLISDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQ 232
Query: 2110 ESFKTSRSSKQRLKIPLVKVDMKEEPLAVSKLTRTSGETTQTHTEPTGDSKSIKAFKESP 2169
+ S SS+Q KI K +P K + +T QT D + +++
Sbjct: 233 DGTPKSISSQQPEKI-------KSQPPGTGKPIQGPTQTPQT------DHAKLPLQRDAS 279
Query: 2170 KQILDPAASVTGSRRQLRTRKEKARALEDLVDFKELFSAPGHTEESMTIDKNTKIPCKSP 2229
+ A V G + ++ K PGH +K+ P K P
Sbjct: 280 RPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGH-------EKSQPGPAKPP 332
Query: 2230 --PPELTDTATS---TKRCPKTRP--RKEVKEELSAVERLTQTSGQSTHTHKEPASGDEG 2282
P LT T + P P K + L + Q +G ++P+S G
Sbjct: 333 AQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGS-----EKPSSEQPG 387
Query: 2283 IKVLKQRAKKKPNPVEEEPSRRRPRAPKEKAQPLEDLAGFTELSETSGHTQESLTAGKAT 2342
K L Q P ++ + P +PL G ++ G T+ +
Sbjct: 388 PKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPG 447
Query: 2343 KIPCE--SPPLEVVDTTASTKRHLRTRVQKVQVKEEPSAVKFTQTSGETTDADKEPAGED 2400
KIP + P T TK + ++P K + + G
Sbjct: 448 KIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGST 507
Query: 2401 KGIKALKESAKQTPAPAASVTGSRRRPRAPRESAQAIEDLAGFKDPAAGHTEE--SMTDD 2458
K AK +P S ++P + + SAQ P+A + + S T
Sbjct: 508 KPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSP----AKPSAQQSTKPVSQTGS 563
Query: 2459 KTTKIPCKSSPELEDTATSSKRRPRTRAQKVEVKEELLAVGKL----TQTSGETT----- 2509
P SP + S+ P+T E LL V + T T +TT
Sbjct: 564 GKPLQPPTVSPSAKQ--PPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLC 621
Query: 2510 -HTDKEPVGEGKGTKAFKQPAKRKLDAEDVIGSRRQPRAPKEKAQPLEDLASFQELSQTP 2568
+ E K KR L D+ P+ PK K P+ ++ + S P
Sbjct: 622 GFNPNPHLTEVKEWLCLNCQMKRALGG-DLAPVPSSPQ-PKLKTAPVTTTSAVSKSSPQP 679
Query: 2569 GHTEELANGAAD---SFTSAPKQTPDSGKPLKISRRVLRAPKVEPVGDVVSTRDPVKSQS 2625
T + A S PK+ P K + K P D +S P K
Sbjct: 680 QQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPK--- 736
Query: 2626 KSNTSLPPLPFKRGGGKDGSVTGTKRLRCMPAPEEIVEELPASKK-----QRVAPRARGK 2680
S+P K D K+ + + ++V A+ K +V +A K
Sbjct: 737 --EPSVPSEQDKAPVADD----KPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEK 790
Query: 2681 SSEPVVIMKRSLRTSAKRIEPAEELNSNDMKTNKEEHKLQDSVPENKGISLRSRRQNKTE 2740
++ P + S + S E+++ D K + + G S S+ Q + +
Sbjct: 791 TTPP--LKTDSAKPSQSFPPTGEKVSPFDSKAIPRPAS-DSKIISHPGPSSESKGQKQVD 847
Query: 2741 AEQQITEVFVLAERIEINRNEKKPMKTSPEMDIQNPDDGARKPIPRD--KVTENKR---- 2794
Q+ E ++ + K K SP P G P P+ K E R
Sbjct: 848 PVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSL 907
Query: 2795 CLRSARQNESSQPKVAEES 2813
L S SQP +E+
Sbjct: 908 NLGSITDAPKSQPTTPQET 926
Score = 32.7 bits (73), Expect = 5.3
Identities = 74/330 (22%), Positives = 126/330 (38%), Gaps = 53/330 (16%)
Query: 40 QLPVVSKQHCKIEIHEQEAILHNFSSTN-----PTQVNGSVIDEPVRLKHGDVITIIDRS 94
Q+ +V KQ +++ ++ IL T P V E +L+ + ++
Sbjct: 1153 QVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLEKDKASALQEKK 1212
Query: 95 FRYENESL---QNGRKSTEFPRKIREQEPA---RRVSRSSFSSDPDESEGIPLKRRRVSF 148
E + L + +S E + E++P +++ + +S P+E + LK +
Sbjct: 1213 PLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHDLLKSQV--- 1269
Query: 149 GGHLRPELFDENLPPNTPLKRGEAPTKRKSLVMHTPPVLKK-------IIKEQPQPSGKQ 201
+ E + + P T + + TK + L TP L K IKEQPQP
Sbjct: 1270 --QIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQPQPPC-- 1325
Query: 202 ESGSEIHVEVKAQSLVISPPAPSPRKTPVASDQRRRSCKTAPAS-SSKSQTEVPKRGGRK 260
+ VE P KT D+ S P S S T G
Sbjct: 1326 -TAKPDQVE------------PGKEKTEKEDDKSDTSSSQQPKSPQGLSDTGYSSDGISS 1372
Query: 261 S-GNLPSKRVSISRSQHDILQMI----CSKRRSGASEANLIVAKSWADVVKLGAKQTQTK 315
S G +PS I + DIL+ + S+ S +S ++L AK + V+ + Q T
Sbjct: 1373 SLGEIPS---LIPTDEKDILKGLKKDSFSQESSPSSPSDL--AKLESTVLSILEAQASTL 1427
Query: 316 VIKHGPQRSMNKRQRRPATPKKPVGEVHSQ 345
++S K Q +P++P + +Q
Sbjct: 1428 ----ADEKSEKKTQPHEVSPEQPKDQEKTQ 1453
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 75.5 bits (184), Expect = 7e-13
Identities = 328/1587 (20%), Positives = 532/1587 (33%), Gaps = 271/1587 (17%)
Query: 1363 TKESMTNEKTTKVSYRASQPDLVDTPTSSKPQ-PKRSLRKADTEEEFLAFRKQTPSA--- 1418
T +S+++++ K+ SQP P Q P+ K + + A R QT A
Sbjct: 235 TPKSISSQQPEKIK---SQPPGTGKPIQGPTQTPQTDHAKLPLQRD--ASRPQTKQADIV 289
Query: 1419 -GKAMHTPKPAVGEEKDINTFLGTPVQKLDQPGNLPGSNRRLQTRKEKAQALEELTGFRE 1477
G+++ P+ + G P P PG + + LT +
Sbjct: 290 RGESVKPSLPSPSKPPIQQPTPGKP------PAQQPGHEKSQPGPAKPPAQPSGLT--KP 341
Query: 1478 LFQTPCTDNPTTDEKTTKKILCK--SPQSDPADTPTNTKQRPKRSLKKADVEEEFLAFRK 1535
L Q P T P T K + P PA + K ++ KA +
Sbjct: 342 LAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQP------- 394
Query: 1536 LTPSAGKAMHTPKAAVGEEKDINTFVGTPVEKLDLLG-----NLPGSKRRPQTPKEKAKA 1590
P GK TP G K VGTP G PG + P K
Sbjct: 395 --PGVGK---TPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKI 449
Query: 1591 LEDLAGFKELFQTPGHTEESMTDDKITEVSCKSP------QPDPVKTPTSSKQRLKISLG 1644
AG PG T T P QP P K P K
Sbjct: 450 PAQQAG-------PGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQ 502
Query: 1645 KVGVK----EEVLPVGKLTQTSGKTTQTHRETAGDGKSIKA---FKESAKQMLDPANY-G 1696
+ G ++ P Q G T ++ S + K SA+Q P + G
Sbjct: 503 QPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTG 562
Query: 1697 TGMERWPRTPKEEAQSLEDLAGFKELFQTPDHTEESTTDD--KTTKIACKSPPPESMDTP 1754
+G P T A+ Q P T TT++ P + +T
Sbjct: 563 SGKPLQPPTVSPSAK------------QPPSQGLPKTICPLCNTTELLLHVPEKANFNTC 610
Query: 1755 TSTRRRPKTPLGKR------DIVEELSALKQLTQTTHTDKVPGDEDKGINVFRETAKQKL 1808
T + + G ++ E L Q+ + D P + +TA
Sbjct: 611 TECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKL--KTAPVTT 668
Query: 1809 DPAASVTGSKRQPRTPKGKAQPLEDLAGLKELFQTPICTDKPTTHEKTTKIACRSPQPDP 1868
A S + + Q +PK A P +DL+ E + P +PT H + A + P+ D
Sbjct: 669 TSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADS 728
Query: 1869 VGTPTIFKPQSKRSLR-KADVEEES----LALRKRTPSVGKAMDTPKP--AGGDEKDMKA 1921
+ P K S S + KA V ++ ++ T V + T KP +
Sbjct: 729 LSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAE 788
Query: 1922 FMGTPVQKLDLPGNLPGSKRWPQTPKE----KAQALEDLAGFKELFQTPGTDKPTTDEKT 1977
TP K D + S+ +P T ++ ++A+ A ++ PG P+++ K
Sbjct: 789 EKTTPPLKTD---SAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPG---PSSESKG 842
Query: 1978 TKIACKSPQPDPVDTPASTKQRPKRNLRKADVEEEFLALRKRT-------PSAGKAMDTP 2030
K Q DPV K+ PK+ K + + + K + P+AG+ + TP
Sbjct: 843 QK------QVDPV----QKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTP 892
Query: 2031 KPAVSDEKNINTFVETPVQKLDLLGNLPGSKRQPQTPKEKAEALEDLVGFKELFQTPGHT 2090
+ + ++ F L+L K QP TP+E L GF G +
Sbjct: 893 QQSPKPQEQSRRF------SLNLGSITDAPKSQPTTPQETVTG--KLFGF-------GAS 937
Query: 2091 EESMTDDKITEVSCKSPQPESFKTSRSSKQRLKIPLVKVDMKEEPLAVSKLTRTSGETTQ 2150
S + I+ P +S + MK+ P A S+ + G
Sbjct: 938 IFSQASNLISTAGQPGPHSQSGPGA--------------PMKQAP-APSQPPTSQGPPKS 982
Query: 2151 THTEPTGDSKSIKAFKES---PKQILDPAASVTGSRRQLRTRKEKARALEDLVDFKELFS 2207
T P +KSI KE+ + L+P A + ++ T K+ + D K L +
Sbjct: 983 TGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKP----PPIKDSKSLTA 1038
Query: 2208 APGHTEESMTIDKNTK-------------IPCKSPPPELTDTATSTKRC-----PKTRPR 2249
P ++K+ K I K PP T T + C T
Sbjct: 1039 EPQKAVLPTKLEKSPKPESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHL 1098
Query: 2250 KEVKEELSA-VERLTQTSGQSTHTHKEPASGDEGIKVLKQRAKKKPNPVEEEPSRRRPRA 2308
E++E L + SGQ K P + K P PV E S ++
Sbjct: 1099 TEIQEWLCLNCQTQRAISGQLGDIRKMPPA--------PSGPKASPMPVPTESSSQKTAV 1150
Query: 2309 PKEKAQPLEDLAGFTELSETSGHTQESLTAGKATKIPCESPPLEVVDTTASTKRHLRTRV 2368
P P L E + + L K T + PP+ D + + +
Sbjct: 1151 P-----PQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLEKDKA 1205
Query: 2369 QKVQVKEE--------PSAVKFTQTSGETTDADKEPAGEDKGIKALKESAKQTPAP---- 2416
+Q K+ P K + +K+P EDK K L E+ P
Sbjct: 1206 SALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDK--KLLPEAKTSAPEEQKHD 1263
Query: 2417 --------AASVTGSRRRPRAPRESAQAIEDLAGFKDPAAGHTEESMTDDKTTKIPCKSS 2468
A R P+ +E Q + G P+ DDKTTK K
Sbjct: 1264 LLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGL--PSGTPQSLPKEDDKTTK-TIKEQ 1320
Query: 2469 PELEDTATSSKRRPRTRAQKVEVKEELLAVGKLTQTSGETTHTDKEPVGEGKGTKAFKQP 2528
P+ TA + P +K E +++ Q +D +G + + P
Sbjct: 1321 PQPPCTAKPDQVEP--GKEKTEKEDDKSDTSSSQQPKSPQGLSDTGYSSDGISSSLGEIP 1378
Query: 2529 AKRKLDAEDVI-GSRRQPRAPKEKAQPLEDLASFQE--LSQTPGHTEELANGAADSFTS- 2584
+ D +D++ G ++ + + DLA + LS LA+ ++ T
Sbjct: 1379 SLIPTDEKDILKGLKKDSFSQESSPSSPSDLAKLESTVLSILEAQASTLADEKSEKKTQP 1438
Query: 2585 ---APKQTPDSGKPLKISRRVLRAPKVEPVGDVVSTRDPVKSQSKSNTSLPPLPFKRGGG 2641
+P+Q D K +S E + +S + +SQ + + FK+
Sbjct: 1439 HEVSPEQPKDQEKTQSLS---------ETLEITISEEEIKESQEERKDT-----FKKDSQ 1484
Query: 2642 KDGSVTGTKRLRCMPAPEEIVEELPASKKQRVAPRARGKSSEPVVIMKRSLRTSAKRIEP 2701
+D + +K + E V+++ ++++ SE + +R RTS
Sbjct: 1485 QD--IPSSKDHK---EKSEFVDDI-TTRREPYDSVEESSESENSPVPQRKRRTSVG---- 1534
Query: 2702 AEELNSNDMKTNKEEHKLQDSVPENKGISLRSRRQNKTEAEQQITEVFVLAERIEINRNE 2761
++ +E+K +DS +G K E E +E E RN+
Sbjct: 1535 ---------SSSSDEYKQEDS----QGSGEEEDFIRKQIIEMSADEDASGSEDDEFIRNQ 1581
Query: 2762 KKPMKTSPEMDIQNPDDGARKPIPRDKVTENKRCLRSARQNESSQPKVAEESGGQKSAKV 2821
K + +S E + G + K+T K R S + E++G + S
Sbjct: 1582 LKEISSSTESQKKEETKG------KGKITAGKH----RRLTRKSSTSIDEDAGRRHS--- 1628
Query: 2822 LMQNQKGKGEAGNSDSMCLRSRKTKSQ 2848
+ + +S L+ R+TKSQ
Sbjct: 1629 ----WHDEDDEAFDESPELKYRETKSQ 1651
Score = 73.2 bits (178), Expect = 4e-12
Identities = 381/1976 (19%), Positives = 666/1976 (33%), Gaps = 287/1976 (14%)
Query: 845 PGSKRQLQTPKEKAQALEDLAGFKELFQTPGHTEELVAAGKTTKIPCDSPQSDPVDTPTS 904
PG+ + +Q P + Q + P + + G++ K SP P+ PT
Sbjct: 252 PGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTP 311
Query: 905 TKQRPKRSIRKADVEGELLACRNLMPSAGKAMHTPKPSVGEEKDIIIFVGT---PVQKLD 961
K ++ + G A +PS G K + GT PVQ
Sbjct: 312 GKPPAQQPGHEKS-------------QPGPAKPPAQPS-GLTKPLAQQPGTVKPPVQPPG 357
Query: 962 LTE---NLTGSKRRPQTPKEEAQALEDLTGFKELFQTPGHTEEAVAAGKT-TKMPCESSP 1017
T+ G + P + + G K L Q PG GKT + P + P
Sbjct: 358 TTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPG-------VGKTPAQQPGPAKP 410
Query: 1018 P-ESADTPTSTRRQP------------KTPLEKRDVQK----ELSALKKLTQTSGETTHT 1060
P + TP +QP KTP+++ K + K Q +G T
Sbjct: 411 PTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPP 470
Query: 1061 DKVPGGEDKSINAFRETAKQKLDPAASVTGSKRHPKTKEKAQPLEDLAGLKELFQTPVCT 1120
++PG P ++ S++ TK P + K Q P T
Sbjct: 471 SQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKP---PPQQPGPAKPSPQQPGST 527
Query: 1121 DKPTTHEKTTKIACRSQPDPV--DTPTSSKPQSKRSLRKVDVEEEFFALRKRTPSAGKA- 1177
P+ + K + + QP P S+KP S+ K K+ PS G
Sbjct: 528 KPPSQQPGSAKPSAQ-QPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPK 586
Query: 1178 ------------MHTPKPAVSGEKNIYAFMGTPVQKL---DLTENLTGSKRRLQTPKEKA 1222
+H P+ A N T V L + +LT K L +
Sbjct: 587 TICPLCNTTELLLHVPEKA---NFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMK 643
Query: 1223 QALE-DLAGFKELFQTRGHTEESMTNDKTAKVACKSSQPDPDKNPASSKRRLK------- 1274
+AL DLA Q + T T +K + + Q P K+ A + K
Sbjct: 644 RALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKP 703
Query: 1275 -------------TSLGKVGVKEELLAVGKLTQTSGETTHTHTEPTGDGKSMKAFMESPK 1321
++ K + + L+ + + P D K + M P
Sbjct: 704 PPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPT 763
Query: 1322 QILDSAASLTGSKRQLRTPKGKSEVPEDLAGFIELFQTPSHTKESMTNEKTTKVSYRASQ 1381
L S++S T +K + + K +S+ E ++ T EK + +A
Sbjct: 764 TDLVSSSSAT-TKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIP 822
Query: 1382 PDLVDTPTSSKPQPKRSLRKADTEEEFLAFRKQTPSAGKAMHTPKPAVGEEKDINTFLGT 1441
D+ S P P S K + + + +K+ P + +PKP + K + T
Sbjct: 823 RPASDSKIISHPGPS-SESKGQKQVDPVQ-KKEEPKKAQTKMSPKP---DAKPMPKGSPT 877
Query: 1442 PVQKLDQPGNLPGSNRRLQTRKEKAQALEELTGFR----ELFQTPCTDNPTTDEKTTKKI 1497
P PG P + + + T ++ + E+ F + P + T E T K+
Sbjct: 878 P------PGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKL 931
Query: 1498 L---------CKSPQSDPADTPTNTKQRPKRSLKKADVEEEFLAFRKLTPSAGKAMHTPK 1548
+ S +++ P +K+A + + S G+A P
Sbjct: 932 FGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPA 991
Query: 1549 AAVGEEKDINTFVGTPVEKLDLLGNLPGSKRRPQTPKEKA--KALEDLAGFKELFQTPGH 1606
++ +K+ EKL+ + +R +T K+ K + L + P
Sbjct: 992 KSIPVKKETKA---PAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTK 1048
Query: 1607 TEESMTDDKI-----TEVSCKSPQPDPVKTPTSSKQRLKISLGKVGVKEEVLPVGKLTQT 1661
E+S + TE++ S P T T K ++ G P LT+
Sbjct: 1049 LEKSPKPESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCG-------FNPTPHLTEI 1101
Query: 1662 SG---KTTQTHRETAGDGKSIKAFKES-----AKQMLDPANYGTGMERWP---RTPKEEA 1710
QT R +G I+ + A M P + P + K++
Sbjct: 1102 QEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVPTESSSQKTAVPPQVKLVKKQE 1161
Query: 1711 QSLED------LAGFKELFQTPDHTEESTTDDKTTKIACKSPPPESMDTPTSTRRRPKTP 1764
Q ++ L KE TTD K + + D ++ + + P
Sbjct: 1162 QEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLEK------DKASALQEKKPLP 1215
Query: 1765 LGKRDIVEELSALKQLTQTTHTDKVPGDEDKGINVFRETA----------KQKLDPAASV 1814
K+ I EE + + +K P EDK + +T+ K ++ A
Sbjct: 1216 EEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEK 1275
Query: 1815 TGSKRQPRTPKGKAQPLEDLAGLKELFQTPICTDKPTTHEKTTKIACRSPQPDPVGTPTI 1874
+ P+T + QP + GL TP P +KTTK PQP P
Sbjct: 1276 LEGRVAPKTVQEGKQPQTKMEGLPS--GTP--QSLPKEDDKTTKTIKEQPQPPCTAKPDQ 1331
Query: 1875 FKPQSKRSLRKADVEEESLALRKRTPSVGKAMDTPKPAGGDEKDMKAFMGT-PVQKLDLP 1933
+P +++ ++ D + S + + ++P DT + G + P + D+
Sbjct: 1332 VEPGKEKTEKEDDKSDTSSSQQPKSPQ--GLSDTGYSSDGISSSLGEIPSLIPTDEKDIL 1389
Query: 1934 GNLP----GSKRWPQTPKEKAQALEDLAGFKELFQTPGTDKPTTDEKTTKIACKSPQPDP 1989
L + P +P + A+ + E + D+ + ++KT QP
Sbjct: 1390 KGLKKDSFSQESSPSSPSDLAKLESTVLSILEAQASTLADEKS-EKKTQPHEVSPEQPKD 1448
Query: 1990 VDTPASTKQRPKRNLRKADVEEEFLALRKRTPSAGKAMDTPKPAVSDEKNINTFVETPVQ 2049
+ S + + + + +++E + +R + K P+ D K + FV+
Sbjct: 1449 QEKTQSLSETLEITISEEEIKE---SQEERKDTFKKDSQQDIPSSKDHKEKSEFVDDITT 1505
Query: 2050 KLDLLGNLPGSKRQ-----PQTPKEKAEALEDLVGFKELFQTPGHTEESMTDDKITEVSC 2104
+ + ++ S PQ + + +K+ EE +I E+S
Sbjct: 1506 RREPYDSVEESSESENSPVPQRKRRTSVGSSSSDEYKQEDSQGSGEEEDFIRKQIIEMSA 1565
Query: 2105 KSPQPESFKTSRSSKQRLKIPL-VKVDMKEEPLAVSKLT-----RTSGETTQTHTEPTGD 2158
S Q +I + KEE K+T R + +++ + E G
Sbjct: 1566 DEDASGSEDDEFIRNQLKEISSSTESQKKEETKGKGKITAGKHRRLTRKSSTSIDEDAGR 1625
Query: 2159 SKSI-----KAFKESPKQILDPAAS-------VTGSR--RQLRT--------------RK 2190
S +AF ESP+ S VTG R+ +T
Sbjct: 1626 RHSWHDEDDEAFDESPELKYRETKSQESEELVVTGGGGLRRFKTIELNSTIADKYSAESS 1685
Query: 2191 EKARAL----EDLVDFKELFSAP---GHTEESMTIDKNTKIPCKSPPP-----ELTDTAT 2238
+K +L E ++ + L +P E S ++ ++ P SP E +D++
Sbjct: 1686 QKKTSLYFDEEPELEMESLTDSPEDRSRGEGSSSLHASSFTPGTSPTSVSSLDEDSDSSP 1745
Query: 2239 STKRCPKTRPRKE----------VKEELSAVERLTQTSGQSTHTHKEPASGDEGIKVLKQ 2288
S K+ + RK E+ S E L + K+ + K +
Sbjct: 1746 SHKKGESKQQRKARHRPHGPLLPTIEDSSEEEELREEEELLKEQEKQREIEQQQRKSSSK 1805
Query: 2289 RAKKKPNPVEEEPSRRRPRAPKEKAQPLEDLAGFTELSETSGHTQESLTAGKATKIPCES 2348
++KK + + + R RP+ P P+ED + EL + + E L ++ S
Sbjct: 1806 KSKKDKDELRAQRRRERPKTPPSNLSPIEDASPTEELRQAA--EMEELHRSSCSEY---S 1860
Query: 2349 PPLEVVDTTASTKRHLRTRVQKVQVKEEPSAVKFTQTSGETTDADKEPAGEDKGIKALKE 2408
P +E VQKV + P+AV + E + KE G K +K+ +E
Sbjct: 1861 PSIESDPEGFEISPEKIIEVQKVY--KLPTAVSLYSPTDEQSIMQKE--GSQKALKSAEE 1916
Query: 2409 SAKQTPAPAASVTGSRRRPRAPRESAQAIEDLAGFKDPAAG------HTEESMTDDKTTK 2462
++ T + A E + E K+P G + ES+ +D T
Sbjct: 1917 MYEE----MMHKTHKYKAFPAANERDEVFE-----KEPLYGGMLIEDYIYESLVED-TYN 1966
Query: 2463 IPCKSSPELEDTATSSKRRPRTRAQKVEVKEELL--AVGKLTQTSGETTHTD---KEPVG 2517
S + + + R QK+ + E++ + K+T E +
Sbjct: 1967 GSVDGSLLTRQEEENGFMQQKGREQKIRLSEQIYEDPMQKITDLQKEFYELESLHSVVPQ 2026
Query: 2518 EGKGTKAFKQPAKRKL-DAEDVIGSRRQPRAPKEKAQPLEDLASFQELSQTPGHTEELAN 2576
E + +F P ++ D ++ S + R + E+L Q++ TPG
Sbjct: 2027 EDIVSSSFIIPESHEIVDLGTMVTSTEEERKLLDADAAYEELMKRQQMQLTPG------- 2079
Query: 2577 GAADSFTSAPKQTPDSGKPLKISRRVLRAPKVEPVGDVVSTRDPVKSQSKSNTSLP 2632
S+P Q P + + R P V+S S S + S+P
Sbjct: 2080 -------SSPTQAPIGEDMTESTMDFDRMPDASLTSSVLSGASLTDSTSSATLSIP 2128
Score = 60.8 bits (146), Expect = 2e-08
Identities = 297/1426 (20%), Positives = 471/1426 (33%), Gaps = 270/1426 (18%)
Query: 1500 KSPQSDPADTPTNTKQRPKRSLKKADVEEEFLAFRKLTPSAGKAMHTPKAAVGEEKDINT 1559
+S Q P +P+ + +S + D++EE H G ++N
Sbjct: 120 RSEQKLPGRSPSTISLKESKS--RTDLKEE---------------HKSSMMPGFLSEVNA 162
Query: 1560 F--VGTPVEKLDLLGNLPGSKRRPQTPKEKAKALEDLAGFKELFQTPGHTEESMTDDKIT 1617
V + V K + + S+ + +K K ++ G E P ++
Sbjct: 163 LSAVSSVVNKFNPFDLISDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQ 222
Query: 1618 EVSCKSP-QPDPVKTPTSSKQRLKISLGKVGVKEEVLPVGKLTQTSGKTTQTHRETAGDG 1676
+ + P Q D SS+Q KI K + GK Q +T QT D
Sbjct: 223 QGPGRDPLQQDGTPKSISSQQPEKI-------KSQPPGTGKPIQGPTQTPQT------DH 269
Query: 1677 KSIKAFKESAKQMLDPANYGTGMERWPRTPKEEAQSLEDLAGFKELFQTPDHTEESTTDD 1736
+ +++++ A+ G P P ++ K Q P H +
Sbjct: 270 AKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPA 329
Query: 1737 KT-------TKIACKSP----PPESMDTPTSTRRRPKTPLGKRDIVEELSALKQLTQTTH 1785
K TK + P PP P T + P PLG K Q T
Sbjct: 330 KPPAQPSGLTKPLAQQPGTVKPPVQ---PPGTTKPPAQPLGPA---------KPPAQQTG 377
Query: 1786 TDKVPGDEDKGINVFRETAKQKLDPAASVTGSKRQPRTPKGKAQPLEDLAGLKELFQTPI 1845
++K P E G + PA G + P G +PL GL+ + P
Sbjct: 378 SEK-PSSEQPGPKALAQPPGVGKTPAQQ-PGPAKPPTQQVGTPKPLAQQPGLQSPAKAPG 435
Query: 1846 CTDKPTTHEKTTKIACRSPQPDPVGT----PTIFKPQSKRSLRKADVEEESLALRKRTPS 1901
T P KI + P PT KP S+ A + K P
Sbjct: 436 PTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPT--KPPSQLP-GPAKPPPQQPGPAKPPPQ 492
Query: 1902 VGKAMDTPKPAGGDEKDMKAFMGTPVQKLDLPGNLPG-SKRWPQTPKEKAQALEDLAGFK 1960
+ P G K P PG +K PQ P + K
Sbjct: 493 QPGSAKPPSQQPGSTKP--------------PPQQPGPAKPSPQQPGSTKPPSQQPGSAK 538
Query: 1961 ELFQTPGTDKPTTDEKTTKIA---CKSPQPDPVDTPASTKQRPKRNLRKADVEEEFLALR 2017
Q P KP+ + T ++ P P +P S KQ P + L K +
Sbjct: 539 PSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSP-SAKQPPSQGLPK--------TIC 589
Query: 2018 KRTPSAGKAMDTPKPAVSDEKNINTFVETPVQKLDLLGNLPGSKRQPQTPKEK------A 2071
+ + P+ A N NT E L G P P + K
Sbjct: 590 PLCNTTELLLHVPEKA-----NFNTCTECQTTVCSLCGFNP----NPHLTEVKEWLCLNC 640
Query: 2072 EALEDLVGFKELFQTPGHTEESMTDDKIT---EVSCKSPQPE--SFKTSRSSKQRL-KIP 2125
+ L G +L P + + +T VS SPQP+ S K + KQ L K P
Sbjct: 641 QMKRALGG--DLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAP 698
Query: 2126 LVKVDMKEEPLAVSKLTRTSGETTQTHTEPTGDSKSIKAFKESPKQILDPAASVTGSRRQ 2185
+ K+ P V + T + + P DS S A PK+ P+
Sbjct: 699 ----EPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPA---PPKEPSVPSEQDKAPVAD 751
Query: 2186 LRTRKEK-ARALEDLVDFKELFSAPGHTEESMTIDKNTKIPCKSPPPELTDTATSTKRCP 2244
+ ++ K + DLV + P + ++ K+ PP TD+A ++ P
Sbjct: 752 DKPKQPKMVKPTTDLVSSSSATTKPDIPSSKV----QSQAEEKTTPPLKTDSAKPSQSFP 807
Query: 2245 KTRPRKEVKEELSAVERLTQTSGQSTHTHKEPASGDEGIKVLKQRAKKKPNPVEEEPSRR 2304
T K + A+ R S +H P+S +G +K+ +PV++ +
Sbjct: 808 PT-GEKVSPFDSKAIPR--PASDSKIISHPGPSSESKG--------QKQVDPVQK---KE 853
Query: 2305 RPRAPKEKAQPLEDLAGFTELSETSGHTQESLTAGKATKIPCESPPLEVVDTTASTKRHL 2364
P+ + K P D + S T + TAG+ P +SP
Sbjct: 854 EPKKAQTKMSPKPDAKPMPKGSPTPPGPRP--TAGQTVPTPQQSP--------------- 896
Query: 2365 RTRVQKVQVKEEPSAVKFTQTSGETTDADKEP--------AGEDKGIKALKESAKQTPAP 2416
K + + +F+ G TDA K G+ G A S
Sbjct: 897 ---------KPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLIS 947
Query: 2417 AASVTG--SRRRPRAPRESAQAIEDLAGFKDPAAGHTEESMTDDKTT----KIPCKSSPE 2470
A G S+ P AP + A PA S K+T P KS P
Sbjct: 948 TAGQPGPHSQSGPGAPMKQA-----------PAPSQPPTSQGPPKSTGQAPPAPAKSIPV 996
Query: 2471 LEDTATSSKRRPRTRAQKVEVKEELLAVGKLTQTS------GETTHTDKEPVGEGKGTKA 2524
++T + A+K+E K E K T+T ++ EP TK
Sbjct: 997 KKETKAPA-------AEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKL 1049
Query: 2525 FKQPAKRK----LDAEDVIGSRRQPR---APKEKAQ--------PLEDLASFQELSQTPG 2569
K P E IGS+ P + K Q P L QE
Sbjct: 1050 EKSPKPESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNC 1109
Query: 2570 HTEELANGAADSFTSAPKQTPDSGKPLKISRRVLRAPKVEPVGDVVSTRDPVKSQSKSNT 2629
T+ +G P PK P+ PV ++S S
Sbjct: 1110 QTQRAISGQLGDIRKMPPAP--------------SGPKASPM--------PVPTESSSQK 1147
Query: 2630 SLPPLPFKRGGGKDGSV-TGTKRLRCMPAPEEI-VEELP----ASKKQRVAPRARGKSSE 2683
+ P K ++ V T +++ E + +E++P +KQ + + K+S
Sbjct: 1148 TAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLEKDKAS- 1206
Query: 2684 PVVIMKRSLRTSAKRIEPAEELNSNDMKTNKEEHKLQDSVPENKGISLRSRRQNKTEAEQ 2743
+ K+ L K I E++ S + K EE K PE+K + ++ E +
Sbjct: 1207 -ALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKK---PTPEDKKLLPEAKTSAPEEQKH 1262
Query: 2744 QI--TEVFVLAERIEINRNEKKPMK--TSPEMDIQNPDDGARKPIPR--DKVTENKR--- 2794
+ ++V + E++E R K ++ P+ ++ G + +P+ DK T+ +
Sbjct: 1263 DLLKSQVQIAEEKLE-GRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQP 1321
Query: 2795 ---CLRSARQNESSQPKVAEESGGQKSAKVLMQNQKGKGEAGNSDS 2837
C Q E + K +E ++ +Q+ K G SD+
Sbjct: 1322 QPPCTAKPDQVEPGKEKTEKEDDKSDTS----SSQQPKSPQGLSDT 1363
Score = 52.4 bits (124), Expect = 7e-06
Identities = 272/1367 (19%), Positives = 472/1367 (34%), Gaps = 252/1367 (18%)
Query: 597 KCAPMSDLTDL-KSLPD---TELMKDTARGQNLLQTQDHAKAPK-----------SEKGK 641
K AP++ + + KS P T KD A Q+L + + K P S K K
Sbjct: 662 KTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAK 721
Query: 642 ITKMPCQSLQPEPINTPTHTKQQLKASLGKVGVKEELLAVGKFTRTSGETTHTHRE-PAG 700
+P P P+ +Q KA + K+ + S + T + P+
Sbjct: 722 QPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSS 781
Query: 701 DGKSIRTFKESPKQILDPAARVTGMKKWPRTPKE----EAQSLEDLAGFKELFQTPGPSE 756
+S K +P D A + +P T ++ +++++ A ++ PGPS
Sbjct: 782 KVQSQAEEKTTPPLKTDSAKP---SQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSS 838
Query: 757 ESMTDEKTTKIACKSPPPESVDTPTSTKQWPKRSLRKADVEEEFLALRKLTPSAGKAMLT 816
ES ++ + K P ++ TK PK + + + P+AG+ + T
Sbjct: 839 ESKGQKQVDPVQKKEEPKKA-----QTKMSPKPDAK--PMPKGSPTPPGPRPTAGQTVPT 891
Query: 817 PKPAGGDEKDIKAFMGTPVQKLDLAGTLPGSKRQLQTPKEKAQALEDLAGF--------K 868
P+ + ++ + F L+L K Q TP+E L GF
Sbjct: 892 PQQSPKPQEQSRRF------SLNLGSITDAPKSQPTTPQETVTG--KLFGFGASIFSQAS 943
Query: 869 ELFQT---PGHTEELVAAGKTTKIPCDSPQSDPVDTPTSTKQRPKRSIRKADVEGELL-- 923
L T PG + + P S P ST Q P + V+ E
Sbjct: 944 NLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAP 1003
Query: 924 ACRNLMPSAGKAMHTPK-------PSVGEEKDII-----IFVGTPVQK---------LDL 962
A L P A +A + P + + K + + T ++K L
Sbjct: 1004 AAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCK 1063
Query: 963 TENLTGSKRRP--QTPKEEAQALEDLTGF---------KELFQTPGHTEEAVAA--GKTT 1009
TE GSK P T E + +L GF +E T+ A++ G
Sbjct: 1064 TELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIR 1123
Query: 1010 KMPCESSPPESADTPTSTRRQ-------PKTPLEKRDVQK-ELSALKKLTQTSGETTHTD 1061
KMP S P+++ P T P+ L K+ Q+ + A K + + ET +
Sbjct: 1124 KMPPAPSGPKASPMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSME 1183
Query: 1062 KVPGGEDKSINAFRETAKQKLDPAASVTGSKRHPKTKEKAQPLEDLAGLKELFQTPVCTD 1121
K+P + + +E +K + D A+++ K P+ K K P E+ +E + P+ +
Sbjct: 1184 KIP--PMVTTDQKQEESKLEKDKASALQEKKPLPEEK-KLIPEEEKIRSEE--KKPLLEE 1238
Query: 1122 KPTTHEKTTKIACRSQPDPVDTPTSSKPQSKRSLRKVDVEEEFFALRKRTPSAGKAMHTP 1181
K T E + + TS+ + K L K V+ L R P
Sbjct: 1239 KKPTPEDKKLLP--------EAKTSAPEEQKHDLLKSQVQIAEEKLEGRV--------AP 1282
Query: 1182 KPAVSGEKNIYAFMGTPVQKLDLTENLTGSKRRLQTPKEKAQALEDLAGFKELFQTRGHT 1241
K G++ G P +G+ + L PKE
Sbjct: 1283 KTVQEGKQPQTKMEGLP----------SGTPQSL--PKE--------------------- 1309
Query: 1242 EESMTNDKTAKVACKSSQPDPDKNPASSKRRLKTSLGKVGVKEELLAVGKLTQTSGETTH 1301
+DKT K + QP P +++ K +++ Q
Sbjct: 1310 -----DDKTTKTIKEQPQPPCTAKP----DQVEPGKEKTEKEDDKSDTSSSQQPKSPQGL 1360
Query: 1302 THTEPTGDGKSMKAFMESPKQI-LDSAASLTGSKRQLRTPKGKSEVPEDLAGFIELFQTP 1360
+ T + DG S + E P I D L G K+ + + P DLA
Sbjct: 1361 SDTGYSSDGIS-SSLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSPSDLAKL------- 1412
Query: 1361 SHTKESMTNEKTTKVSYRASQPDLVDTPTSSKPQPKRSLRKADTEEEFLAFRKQTPSAGK 1420
E T A L D + K QP + ++E +T
Sbjct: 1413 ---------ESTVLSILEAQASTLADEKSEKKTQPHEVSPEQPKDQEKTQSLSETLEITI 1463
Query: 1421 AMHTPKPAVGEEKDINTFLGTPVQKLDQPGNLPGSNRRLQTRKEKAQALEELTGFRELFQ 1480
+ K + E KD TF K D ++P S + KEK++ ++++T RE +
Sbjct: 1464 SEEEIKESQEERKD--TF------KKDSQQDIPSS----KDHKEKSEFVDDITTRREPYD 1511
Query: 1481 TPCTDNPTTDEKTTKKILCKSPQSDPADTPTNTKQRPKRSLKKADVEEEFLAFRKLTPSA 1540
+ + + + ++ S S +D + + + + EE+F+ + + SA
Sbjct: 1512 SVEESSESENSPVPQRKRRTSVGSSSSD------EYKQEDSQGSGEEEDFIRKQIIEMSA 1565
Query: 1541 ---GKAMHTPKAAVGEEKDINTFV-GTPVEKLDLLGNLPGSKRRPQTPKEKAKALEDLAG 1596
+ + K+I++ E+ G + K R T K ED AG
Sbjct: 1566 DEDASGSEDDEFIRNQLKEISSSTESQKKEETKGKGKITAGKHRRLTRKSSTSIDED-AG 1624
Query: 1597 FKELFQTPGHTEESMTDDKITEVSCKSPQPDPVKTPTSSKQRLKISLGKVGVKEEVLPVG 1656
+ + H E+ D+ E+ + T S++ EE++ G
Sbjct: 1625 RRHSW----HDEDDEAFDESPELKYRE---------TKSQE-----------SEELVVTG 1660
Query: 1657 KLTQTSGKTTQTHRETAGDGKSIKAFKESAKQMLDPANYGTGMERWPRTPKEEAQSLEDL 1716
KT + + T D S ++ ++ D P+ E +SL D
Sbjct: 1661 GGGLRRFKTIELN-STIADKYSAESSQKKTSLYFD------------EEPELEMESLTDS 1707
Query: 1717 AGFKELFQTPDHTEESTTDDKTTKIACKSPPPESMDTPT----------STRRRPKTPLG 1766
+ + S+ T+ + S +S +P+ R RP PL
Sbjct: 1708 PEDRSRGEGSSSLHASSFTPGTSPTSVSSLDEDSDSSPSHKKGESKQQRKARHRPHGPL- 1766
Query: 1767 KRDIVEELSALKQLTQTTHTDKVPGDEDKGINVFRETAKQKLDPAASVTGSKR---QPRT 1823
+E+ S ++L + K + + R+++ +K ++R +P+T
Sbjct: 1767 -LPTIEDSSEEEELREEEELLKEQEKQREIEQQQRKSSSKKSKKDKDELRAQRRRERPKT 1825
Query: 1824 PKGKAQPLEDLAGLKELFQTPICTDKPTTHEKTTKIACRSPQPDPVG 1870
P P+ED + +EL Q + H + S + DP G
Sbjct: 1826 PPSNLSPIEDASPTEELRQ---AAEMEELHRSSCSEYSPSIESDPEG 1869
Score = 38.9 bits (89), Expect = 0.075
Identities = 93/467 (19%), Positives = 160/467 (34%), Gaps = 60/467 (12%)
Query: 2217 TIDKNTKIPCKSPPPELTDTATSTKRCPKTRPRKEVKEE---------------LSAVER 2261
T K+P +SP ST +++ R ++KEE LSAV
Sbjct: 118 TFRSEQKLPGRSP---------STISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSS 168
Query: 2262 LTQTSGQSTHTHKEPASGDEGIKVLK--QRAKKKPNPVEEEPSRRRPRAPKEKAQPLEDL 2319
+ AS +E K K Q+ + KP + + P +++P P K Q
Sbjct: 169 VVNKFNPFDLISDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQG---- 224
Query: 2320 AGFTELSETSGHTQESLTAGKATKIPCESP----PLEVVDTTAST---KRHLRTRVQKVQ 2372
G L + T +S+++ + KI + P P++ T T K L+ + Q
Sbjct: 225 PGRDPLQQDG--TPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQ 282
Query: 2373 VKE---------EPSAVKFTQTSGETTDADKEPAGEDKGIKALKESAKQTPAPAASVTGS 2423
K+ +PS ++ + K PA + K+ AK P+
Sbjct: 283 TKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPL 342
Query: 2424 RRRP-------RAPRESAQAIEDLAGFKDPAAGHTEESMTDDKTTKIPCKSSPELEDTAT 2476
++P + P + + L K PA E + ++ P + T
Sbjct: 343 AQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPA 402
Query: 2477 SSKRRPRTRAQKVEVKEELLAVGKLTQTSGETTHTDKEPVGE-GKGTKAFKQPAKRKLDA 2535
+ Q+V + L L Q+ + K PV + G G +Q K A
Sbjct: 403 QQPGPAKPPTQQVGTPKPLAQQPGL-QSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSA 461
Query: 2536 EDVIGSRRQPRAPKEKAQPLEDLASFQELSQTPGHTEELANGAADSFTSAPKQTPDSGKP 2595
+ ++ + P P + + Q PG + + T P Q P KP
Sbjct: 462 QQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGS--TKPPPQQPGPAKP 519
Query: 2596 LKISRRVLRAPKVEPVGDVVSTRDPVKSQSKSNTSLPPLPFKRGGGK 2642
+ P +P S + P ++ + S P+ + G GK
Sbjct: 520 SPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVS-QTGSGK 565
Score = 33.9 bits (76), Expect = 2.4
Identities = 171/859 (19%), Positives = 281/859 (32%), Gaps = 85/859 (9%)
Query: 1991 DTPASTKQRPKRNLRKADVEEEFLALRKRTPSAGKAMDTPKPAVSDEKNINTFVETPVQK 2050
DT S ++ P R+ ++E + RT + + P E N + V + V K
Sbjct: 117 DTFRSEQKLPGRSPSTISLKES----KSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNK 172
Query: 2051 LDLLGNLPGSKRQPQTPKEKAEALEDLVGFKELFQTPGHTEESMTDDKITEVSCKSP-QP 2109
+ + S+ + +K + ++ G E P ++ + + P Q
Sbjct: 173 FNPFDLISDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQ 232
Query: 2110 ESFKTSRSSKQRLKIPLVKVDMKEEPLAVSKLTRTSGETTQTHTEPTGDSKSIKAFKESP 2169
+ S SS+Q KI K +P K + +T QT D + +++
Sbjct: 233 DGTPKSISSQQPEKI-------KSQPPGTGKPIQGPTQTPQT------DHAKLPLQRDAS 279
Query: 2170 KQILDPAASVTGSRRQLRTRKEKARALEDLVDFKELFSAPGHTEESMTIDKNTKIPCKSP 2229
+ A V G + ++ K PGH +K+ P K P
Sbjct: 280 RPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGH-------EKSQPGPAKPP 332
Query: 2230 --PPELTDTATS---TKRCPKTRP--RKEVKEELSAVERLTQTSGQSTHTHKEPASGDEG 2282
P LT T + P P K + L + Q +G ++P+S G
Sbjct: 333 AQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGS-----EKPSSEQPG 387
Query: 2283 IKVLKQRAKKKPNPVEEEPSRRRPRAPKEKAQPLEDLAGFTELSETSGHTQESLTAGKAT 2342
K L Q P ++ + P +PL G ++ G T+ +
Sbjct: 388 PKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPG 447
Query: 2343 KIPCE--SPPLEVVDTTASTKRHLRTRVQKVQVKEEPSAVKFTQTSGETTDADKEPAGED 2400
KIP + P T TK + ++P K + + G
Sbjct: 448 KIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGST 507
Query: 2401 KGIKALKESAKQTPAPAASVTGSRRRPRAPRESAQAIEDLAGFKDPAAGHTEE--SMTDD 2458
K AK +P S ++P + + SAQ P+A + + S T
Sbjct: 508 KPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSP----AKPSAQQSTKPVSQTGS 563
Query: 2459 KTTKIPCKSSPELEDTATSSKRRPRTRAQKVEVKEELLAVGKL----TQTSGETT----- 2509
P SP + S+ P+T E LL V + T T +TT
Sbjct: 564 GKPLQPPTVSPSAKQ--PPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLC 621
Query: 2510 -HTDKEPVGEGKGTKAFKQPAKRKLDAEDVIGSRRQPRAPKEKAQPLEDLASFQELSQTP 2568
+ E K KR L D+ P+ PK K P+ ++ + S P
Sbjct: 622 GFNPNPHLTEVKEWLCLNCQMKRALGG-DLAPVPSSPQ-PKLKTAPVTTTSAVSKSSPQP 679
Query: 2569 GHTEELANGAAD---SFTSAPKQTPDSGKPLKISRRVLRAPKVEPVGDVVSTRDPVKSQS 2625
T + A S PK+ P K + K P D +S P K
Sbjct: 680 QQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPK--- 736
Query: 2626 KSNTSLPPLPFKRGGGKDGSVTGTKRLRCMPAPEEIVEELPASKK-----QRVAPRARGK 2680
S+P K D K+ + + ++V A+ K +V +A K
Sbjct: 737 --EPSVPSEQDKAPVADD----KPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEK 790
Query: 2681 SSEPVVIMKRSLRTSAKRIEPAEELNSNDMKTNKEEHKLQDSVPENKGISLRSRRQNKTE 2740
++ P + S + S E+++ D K + + G S S+ Q + +
Sbjct: 791 TTPP--LKTDSAKPSQSFPPTGEKVSPFDSKAIPRPAS-DSKIISHPGPSSESKGQKQVD 847
Query: 2741 AEQQITEVFVLAERIEINRNEKKPMKTSPEMDIQNPDDGARKPIPRD--KVTENKR---- 2794
Q+ E ++ + K K SP P G P P+ K E R
Sbjct: 848 PVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSL 907
Query: 2795 CLRSARQNESSQPKVAEES 2813
L S SQP +E+
Sbjct: 908 NLGSITDAPKSQPTTPQET 926
Score = 32.7 bits (73), Expect = 5.3
Identities = 74/330 (22%), Positives = 126/330 (38%), Gaps = 53/330 (16%)
Query: 40 QLPVVSKQHCKIEIHEQEAILHNFSSTN-----PTQVNGSVIDEPVRLKHGDVITIIDRS 94
Q+ +V KQ +++ ++ IL T P V E +L+ + ++
Sbjct: 1153 QVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLEKDKASALQEKK 1212
Query: 95 FRYENESL---QNGRKSTEFPRKIREQEPA---RRVSRSSFSSDPDESEGIPLKRRRVSF 148
E + L + +S E + E++P +++ + +S P+E + LK +
Sbjct: 1213 PLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHDLLKSQV--- 1269
Query: 149 GGHLRPELFDENLPPNTPLKRGEAPTKRKSLVMHTPPVLKK-------IIKEQPQPSGKQ 201
+ E + + P T + + TK + L TP L K IKEQPQP
Sbjct: 1270 --QIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQPQPPC-- 1325
Query: 202 ESGSEIHVEVKAQSLVISPPAPSPRKTPVASDQRRRSCKTAPAS-SSKSQTEVPKRGGRK 260
+ VE P KT D+ S P S S T G
Sbjct: 1326 -TAKPDQVE------------PGKEKTEKEDDKSDTSSSQQPKSPQGLSDTGYSSDGISS 1372
Query: 261 S-GNLPSKRVSISRSQHDILQMI----CSKRRSGASEANLIVAKSWADVVKLGAKQTQTK 315
S G +PS I + DIL+ + S+ S +S ++L AK + V+ + Q T
Sbjct: 1373 SLGEIPS---LIPTDEKDILKGLKKDSFSQESSPSSPSDL--AKLESTVLSILEAQASTL 1427
Query: 316 VIKHGPQRSMNKRQRRPATPKKPVGEVHSQ 345
++S K Q +P++P + +Q
Sbjct: 1428 ----ADEKSEKKTQPHEVSPEQPKDQEKTQ 1453
>gi|16554449 zonadhesin isoform 3 [Homo sapiens]
Length = 2812
Score = 69.3 bits (168), Expect = 5e-11
Identities = 109/501 (21%), Positives = 183/501 (36%), Gaps = 62/501 (12%)
Query: 872 QTPGHTEELVAAGKTTKIPCDSPQSDPVDTPTSTKQRPKRSIRKADVEGELLACRNLMPS 931
+T G TE + K + + P S + PT K++P K + E + +PS
Sbjct: 555 ETTGLTENPTISTKKPTVSIEKP-SVTTEKPTVPKEKPTIPTEKPTISTE----KPTIPS 609
Query: 932 AGKAMHTPKPSVGEEKDIIIFVGT--PVQKLDL-TENLTGSKRRPQTPKEEAQALEDLTG 988
M + KP++ EK I+ P +K + +E T S +P P EE +
Sbjct: 610 EKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTE--- 666
Query: 989 FKELFQTPGHTEEAVAAGKTTKMPCE--SSPPE-----------SADTPTSTRRQPKTPL 1035
+T EE V + +P E S P E S + PT + +P P
Sbjct: 667 -----ETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTISPEKPTIPT 721
Query: 1036 EKRDVQKELSAL---KKLTQTSGETTHTDKVPGGEDKSINAFRETAKQKLDPAA-SVTGS 1091
EK + E S + K T T T T+K +K T K + P ++
Sbjct: 722 EKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP---TEKPTISPEKLTIPTE 778
Query: 1092 KRHPKTKEKAQPLEDLAGLKELFQTPVCTDKPTTHEKTTKIACRSQPDPVDTPTSSKPQS 1151
K T++ P E + + T++PTT + T I+ P++ PT ++
Sbjct: 779 KPTIPTEKPTIPTE---------KPTISTEEPTTPTEETTISTEKPSIPMEKPTLPTEET 829
Query: 1152 KRSLRKVDVEEEFFALRKRTPSAG---KAMHTPKPAVSGEKNIYAFMGTPVQKLDL---- 1204
S+ + + E + P+ + T KP +S EK + P +KL +
Sbjct: 830 TTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEK-----LTIPTEKLTIPTEK 884
Query: 1205 ----TENLTGSKRRLQTPKEKAQALEDLAGFKELFQTRGHTEESMTNDKTAKVACKSSQP 1260
E T S +L P EK + T + ++ ++T K + P
Sbjct: 885 PTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKPTIPTEETTISTEKLTIP 944
Query: 1261 DPDKNPASSKRRLKTSLGKVGVKEELLAVGKLTQTSGETTHTHTEPTGDGKSMKAFM-ES 1319
+ K + T + ++ + KLT + + T +PT + + A
Sbjct: 945 TEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIPTEKLTALRPPH 1004
Query: 1320 PKQILDSAASLTGSKRQLRTP 1340
P A+L S TP
Sbjct: 1005 PSPTATGLAALVMSPHAPSTP 1025
Score = 63.5 bits (153), Expect = 3e-09
Identities = 125/542 (23%), Positives = 186/542 (34%), Gaps = 66/542 (12%)
Query: 1602 QTPGHTEESMTDDKITEVSCKSPQPD------PVKTPTSSKQRLKISLGKVGVKEEV--L 1653
+T G TE K VS + P P + PT ++ IS K + E +
Sbjct: 555 ETTGLTENPTISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNM 614
Query: 1654 PVGKLTQTSGKTT-QTHRETAGDGKSIKAFKESAKQMLDPANYGTGMERWPRTPKEEAQ- 1711
P K T S K T T + T S K S K + E P TP EE
Sbjct: 615 PSEKPTIPSEKPTILTEKPTI---PSEKPTIPSEKPTISTEKPTVPTEE-PTTPTEETTT 670
Query: 1712 SLEDLAGFKELFQTPDHTEESTTDDKTTKIACKSPPPESMDTPTSTRRRPKTPLGKRDIV 1771
S+E+ E P T+ T + S + PT + +P P K I
Sbjct: 671 SMEEPVIPTEKPSIPTEKPSIPTEKPTISM---EETIISTEKPTISPEKPTIPTEKPTIP 727
Query: 1772 EELSALKQLTQTTHTDK--VPGDEDKGINVFRETAKQKLDPAASVTGSKRQPRTPKGKAQ 1829
E S + TT T+K +P T K + P T +++ +P+
Sbjct: 728 TEKSTISPEKPTTPTEKPTIP------------TEKPTISPEKPTTPTEKPTISPEKLTI 775
Query: 1830 PLEDLAGLKELFQTP-----ICTDKPTTHEKTTKIACRSPQPDPVGTPTIFKPQSKRSLR 1884
P E E P I T++PTT + T I+ P P+ PT+ ++ S+
Sbjct: 776 PTEKPTIPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPMEKPTLPTEETTTSVE 834
Query: 1885 KADVEEESLALRKRTPSVG---KAMDTPKPAGGDEKDMKAFMGTPVQKLDLPGNLPG--- 1938
+ + E L + P++ + T KP EK + P +KL +P P
Sbjct: 835 ETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEK-----LTIPTEKLTIPTEKPTIPI 889
Query: 1939 -----SKRWPQTPKEKAQALEDLAGFKELFQTPGTDKPTTDEKTTKIACKS---PQPDPV 1990
S P EK + T T+KPT + T I+ + P P
Sbjct: 890 EETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKPTIPTEETTISTEKLTIPTEKPT 949
Query: 1991 DTPAS---TKQRPKRNLRKADVEEEFLALRKRTPSAGKAMDTPKPAVSDEKNINTFVETP 2047
+P ++P + K + E L + P+ + T KP + EK P
Sbjct: 950 ISPEKLTIPTEKPTISTEKPTIPTEKLTI----PTEKPTIPTEKPTIPTEKLTALRPPHP 1005
Query: 2048 VQKLDLLGNLPGSKRQPQTPKEKAEALEDLVGFKELFQTPGHTEESMTDDKITEVSCKSP 2107
L L S P TP + P + + SCKSP
Sbjct: 1006 SPTATGLAALVMSPHAPSTPMTSVILGTTTTSRSSTERCP---PNARYESCACPASCKSP 1062
Query: 2108 QP 2109
+P
Sbjct: 1063 RP 1064
Score = 51.2 bits (121), Expect = 1e-05
Identities = 110/516 (21%), Positives = 186/516 (36%), Gaps = 78/516 (15%)
Query: 2085 QTPGHTEESMTDDKITEVSCKSPQPESFKTSRSSKQRLKIPLVKVDMKEEPLAVSKLTRT 2144
+T G TE K VS + P + K + K++ IP K + E K T
Sbjct: 555 ETTGLTENPTISTKKPTVSIEKPSVTTEKPT-VPKEKPTIPTEKPTISTE-----KPTIP 608
Query: 2145 SGETTQTHTEPTGDSKSIKAFKESPKQILDPAASVTGSRRQLRTRKEKARALEDLVDFKE 2204
S + +PT S+ E P I ++ + + T K E +E
Sbjct: 609 SEKPNMPSEKPTIPSEKPTILTEKPT-IPSEKPTIPSEKPTISTEKPTVPTEEPTTPTEE 667
Query: 2205 LFSAPGH----TEESMTIDKNTKIPCKSPPPELTDTATSTKRCPKTRPRKEVKEELSAVE 2260
++ TE+ + IP + P + +T ST++ P P K E
Sbjct: 668 TTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEK-PTISPEKPT----IPTE 722
Query: 2261 RLTQTSGQSTHTHKEPASGDEGIKVLKQR---AKKKPNPVEEEPS---------RRRPRA 2308
+ T + +ST + ++P + E + ++ + +KP E+P+ +P
Sbjct: 723 KPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTPTEKPTISPEKLTIPTEKPTI 782
Query: 2309 PKEKAQ-PLEDLAGFTELSETSGHTQESLTAGKATKIPCESPPLEVVDTTASTKRHLRTR 2367
P EK P E TE E + T+E+ + + IP E P L +TT S + +
Sbjct: 783 PTEKPTIPTEKPTISTE--EPTTPTEETTISTEKPSIPMEKPTLPTEETTTSVEETTIST 840
Query: 2368 VQKVQVKEEPSAVKFTQTSGETTDADKEPAGEDKGIKALKESAKQTPAPAASVTGSRRRP 2427
+ E+P+ T T +K +K P +T +P
Sbjct: 841 EKLTIPMEKPT----ISTEKPTIPTEKPTISPEK-----------LTIPTEKLTIPTEKP 885
Query: 2428 RAPRESAQAIEDLAGFKDPAAGHTEESMTDDKTTKIPCKSSPELEDTATSSKRRPRTRAQ 2487
P E E +++ +K T IP + + T S +P +
Sbjct: 886 TIPIE-------------------ETTISTEKLT-IPTEKPTISPEKPTISTEKPTIPTE 925
Query: 2488 K--VEVKEELLAVGKLT-QTSGETTHTDKEPVGEGKGTKAFKQPAKRKLDAEDVIGSRRQ 2544
K + +E ++ KLT T T +K + K T + ++P + E + +
Sbjct: 926 KPTIPTEETTISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPT---IPTEKLTIPTEK 982
Query: 2545 PRAPKEKAQ-PLEDLASFQELSQTPGHTEELANGAA 2579
P P EK P E L + + P H A G A
Sbjct: 983 PTIPTEKPTIPTEKLTALR-----PPHPSPTATGLA 1013
>gi|27881494 zonadhesin isoform 6 [Homo sapiens]
Length = 2721
Score = 69.3 bits (168), Expect = 5e-11
Identities = 109/501 (21%), Positives = 183/501 (36%), Gaps = 62/501 (12%)
Query: 872 QTPGHTEELVAAGKTTKIPCDSPQSDPVDTPTSTKQRPKRSIRKADVEGELLACRNLMPS 931
+T G TE + K + + P S + PT K++P K + E + +PS
Sbjct: 555 ETTGLTENPTISTKKPTVSIEKP-SVTTEKPTVPKEKPTIPTEKPTISTE----KPTIPS 609
Query: 932 AGKAMHTPKPSVGEEKDIIIFVGT--PVQKLDL-TENLTGSKRRPQTPKEEAQALEDLTG 988
M + KP++ EK I+ P +K + +E T S +P P EE +
Sbjct: 610 EKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTE--- 666
Query: 989 FKELFQTPGHTEEAVAAGKTTKMPCE--SSPPE-----------SADTPTSTRRQPKTPL 1035
+T EE V + +P E S P E S + PT + +P P
Sbjct: 667 -----ETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTISPEKPTIPT 721
Query: 1036 EKRDVQKELSAL---KKLTQTSGETTHTDKVPGGEDKSINAFRETAKQKLDPAA-SVTGS 1091
EK + E S + K T T T T+K +K T K + P ++
Sbjct: 722 EKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP---TEKPTISPEKLTIPTE 778
Query: 1092 KRHPKTKEKAQPLEDLAGLKELFQTPVCTDKPTTHEKTTKIACRSQPDPVDTPTSSKPQS 1151
K T++ P E + + T++PTT + T I+ P++ PT ++
Sbjct: 779 KPTIPTEKPTIPTE---------KPTISTEEPTTPTEETTISTEKPSIPMEKPTLPTEET 829
Query: 1152 KRSLRKVDVEEEFFALRKRTPSAG---KAMHTPKPAVSGEKNIYAFMGTPVQKLDL---- 1204
S+ + + E + P+ + T KP +S EK + P +KL +
Sbjct: 830 TTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEK-----LTIPTEKLTIPTEK 884
Query: 1205 ----TENLTGSKRRLQTPKEKAQALEDLAGFKELFQTRGHTEESMTNDKTAKVACKSSQP 1260
E T S +L P EK + T + ++ ++T K + P
Sbjct: 885 PTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKPTIPTEETTISTEKLTIP 944
Query: 1261 DPDKNPASSKRRLKTSLGKVGVKEELLAVGKLTQTSGETTHTHTEPTGDGKSMKAFM-ES 1319
+ K + T + ++ + KLT + + T +PT + + A
Sbjct: 945 TEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIPTEKLTALRPPH 1004
Query: 1320 PKQILDSAASLTGSKRQLRTP 1340
P A+L S TP
Sbjct: 1005 PSPTATGLAALVMSPHAPSTP 1025
Score = 63.5 bits (153), Expect = 3e-09
Identities = 125/542 (23%), Positives = 186/542 (34%), Gaps = 66/542 (12%)
Query: 1602 QTPGHTEESMTDDKITEVSCKSPQPD------PVKTPTSSKQRLKISLGKVGVKEEV--L 1653
+T G TE K VS + P P + PT ++ IS K + E +
Sbjct: 555 ETTGLTENPTISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNM 614
Query: 1654 PVGKLTQTSGKTT-QTHRETAGDGKSIKAFKESAKQMLDPANYGTGMERWPRTPKEEAQ- 1711
P K T S K T T + T S K S K + E P TP EE
Sbjct: 615 PSEKPTIPSEKPTILTEKPTI---PSEKPTIPSEKPTISTEKPTVPTEE-PTTPTEETTT 670
Query: 1712 SLEDLAGFKELFQTPDHTEESTTDDKTTKIACKSPPPESMDTPTSTRRRPKTPLGKRDIV 1771
S+E+ E P T+ T + S + PT + +P P K I
Sbjct: 671 SMEEPVIPTEKPSIPTEKPSIPTEKPTISM---EETIISTEKPTISPEKPTIPTEKPTIP 727
Query: 1772 EELSALKQLTQTTHTDK--VPGDEDKGINVFRETAKQKLDPAASVTGSKRQPRTPKGKAQ 1829
E S + TT T+K +P T K + P T +++ +P+
Sbjct: 728 TEKSTISPEKPTTPTEKPTIP------------TEKPTISPEKPTTPTEKPTISPEKLTI 775
Query: 1830 PLEDLAGLKELFQTP-----ICTDKPTTHEKTTKIACRSPQPDPVGTPTIFKPQSKRSLR 1884
P E E P I T++PTT + T I+ P P+ PT+ ++ S+
Sbjct: 776 PTEKPTIPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPMEKPTLPTEETTTSVE 834
Query: 1885 KADVEEESLALRKRTPSVG---KAMDTPKPAGGDEKDMKAFMGTPVQKLDLPGNLPG--- 1938
+ + E L + P++ + T KP EK + P +KL +P P
Sbjct: 835 ETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEK-----LTIPTEKLTIPTEKPTIPI 889
Query: 1939 -----SKRWPQTPKEKAQALEDLAGFKELFQTPGTDKPTTDEKTTKIACKS---PQPDPV 1990
S P EK + T T+KPT + T I+ + P P
Sbjct: 890 EETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKPTIPTEETTISTEKLTIPTEKPT 949
Query: 1991 DTPAS---TKQRPKRNLRKADVEEEFLALRKRTPSAGKAMDTPKPAVSDEKNINTFVETP 2047
+P ++P + K + E L + P+ + T KP + EK P
Sbjct: 950 ISPEKLTIPTEKPTISTEKPTIPTEKLTI----PTEKPTIPTEKPTIPTEKLTALRPPHP 1005
Query: 2048 VQKLDLLGNLPGSKRQPQTPKEKAEALEDLVGFKELFQTPGHTEESMTDDKITEVSCKSP 2107
L L S P TP + P + + SCKSP
Sbjct: 1006 SPTATGLAALVMSPHAPSTPMTSVILGTTTTSRSSTERCP---PNARYESCACPASCKSP 1062
Query: 2108 QP 2109
+P
Sbjct: 1063 RP 1064
Score = 51.2 bits (121), Expect = 1e-05
Identities = 110/516 (21%), Positives = 186/516 (36%), Gaps = 78/516 (15%)
Query: 2085 QTPGHTEESMTDDKITEVSCKSPQPESFKTSRSSKQRLKIPLVKVDMKEEPLAVSKLTRT 2144
+T G TE K VS + P + K + K++ IP K + E K T
Sbjct: 555 ETTGLTENPTISTKKPTVSIEKPSVTTEKPT-VPKEKPTIPTEKPTISTE-----KPTIP 608
Query: 2145 SGETTQTHTEPTGDSKSIKAFKESPKQILDPAASVTGSRRQLRTRKEKARALEDLVDFKE 2204
S + +PT S+ E P I ++ + + T K E +E
Sbjct: 609 SEKPNMPSEKPTIPSEKPTILTEKPT-IPSEKPTIPSEKPTISTEKPTVPTEEPTTPTEE 667
Query: 2205 LFSAPGH----TEESMTIDKNTKIPCKSPPPELTDTATSTKRCPKTRPRKEVKEELSAVE 2260
++ TE+ + IP + P + +T ST++ P P K E
Sbjct: 668 TTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEK-PTISPEKPT----IPTE 722
Query: 2261 RLTQTSGQSTHTHKEPASGDEGIKVLKQR---AKKKPNPVEEEPS---------RRRPRA 2308
+ T + +ST + ++P + E + ++ + +KP E+P+ +P
Sbjct: 723 KPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTPTEKPTISPEKLTIPTEKPTI 782
Query: 2309 PKEKAQ-PLEDLAGFTELSETSGHTQESLTAGKATKIPCESPPLEVVDTTASTKRHLRTR 2367
P EK P E TE E + T+E+ + + IP E P L +TT S + +
Sbjct: 783 PTEKPTIPTEKPTISTE--EPTTPTEETTISTEKPSIPMEKPTLPTEETTTSVEETTIST 840
Query: 2368 VQKVQVKEEPSAVKFTQTSGETTDADKEPAGEDKGIKALKESAKQTPAPAASVTGSRRRP 2427
+ E+P+ T T +K +K P +T +P
Sbjct: 841 EKLTIPMEKPT----ISTEKPTIPTEKPTISPEK-----------LTIPTEKLTIPTEKP 885
Query: 2428 RAPRESAQAIEDLAGFKDPAAGHTEESMTDDKTTKIPCKSSPELEDTATSSKRRPRTRAQ 2487
P E E +++ +K T IP + + T S +P +
Sbjct: 886 TIPIE-------------------ETTISTEKLT-IPTEKPTISPEKPTISTEKPTIPTE 925
Query: 2488 K--VEVKEELLAVGKLT-QTSGETTHTDKEPVGEGKGTKAFKQPAKRKLDAEDVIGSRRQ 2544
K + +E ++ KLT T T +K + K T + ++P + E + +
Sbjct: 926 KPTIPTEETTISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPT---IPTEKLTIPTEK 982
Query: 2545 PRAPKEKAQ-PLEDLASFQELSQTPGHTEELANGAA 2579
P P EK P E L + + P H A G A
Sbjct: 983 PTIPTEKPTIPTEKLTALR-----PPHPSPTATGLA 1013
>gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d
[Homo sapiens]
Length = 1488
Score = 65.9 bits (159), Expect = 6e-10
Identities = 309/1502 (20%), Positives = 510/1502 (33%), Gaps = 221/1502 (14%)
Query: 1522 KKADVEEEFLAFRKLTPSAGKAMHTPKAAVGEEKDINTFVGTPVEKLDLLGNLPGSKRRP 1581
+K EE+ K T + + + EE + T TP +L + P
Sbjct: 61 RKRKAEEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATP--RLASTNSSVLGADLP 118
Query: 1582 QTPKEKAKALEDLAGFKELFQTPGHTEESMTDDKITEVSCKSPQPDPVKTPTS-SKQRLK 1640
+ KEKAKA + AG T +++ + + KS +P T S +++
Sbjct: 119 SSMKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGS 178
Query: 1641 ISLGKVGVKEEVLPVGKLTQTSGKTTQTHRETAGDGK-SIK---------AFKESAKQML 1690
+ K ++ G+ +S T+ + ET +GK S+K + KES +
Sbjct: 179 VPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKA 238
Query: 1691 DPANYGTGMERWPRTPKEEAQSLEDLAGFKELFQTPDHTEESTTDDKTTKIACKSPPPES 1750
PA G TP+ + +L K+ + + +EE + ++
Sbjct: 239 APAPGKVG----DVTPQVKGGALPPAKRAKKPEEESESSEEGSESEE------------- 281
Query: 1751 MDTPTSTRRRPKTPLGKRDIVEELSALKQLTQTTHTDKVPGDEDKGINVFRETAKQKLDP 1810
+ P TR + K I++ +A T P K V +T K +
Sbjct: 282 -EAPAGTRSQVKA---SEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEE 337
Query: 1811 ---AASVTGSKRQPRTPKGKAQPLEDLAGLKELFQTPICTDKPTTHEKTTKIACRSPQPD 1867
++S S + TP KA +G + + E K A +P P
Sbjct: 338 DSESSSEESSDSEEETPAAKALLQAKASGKT----SQVGAASAPAKESPRKGAAPAP-PG 392
Query: 1868 PVGTPTIFKPQ-------SKRSLRKADVEEESLALRK---RTPSV----GKAMDTPKPAG 1913
G P + K Q S+ S ++D EEE+ A K + P V A ++P+
Sbjct: 393 KTG-PAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGA 451
Query: 1914 GDEKDMKAFMGTPVQKLDLPGNLPGSKRWPQTPKEKAQALEDLAGFKELFQTPGTDKPTT 1973
K ++ S +A A + A K L ++P +T
Sbjct: 452 APAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPAST 511
Query: 1974 DEKTTKIACKSPQPDPVDTPASTKQRPKRNLRKADVEEEFLALRKRTPSAGKAMDTPKPA 2033
P P PA+ P + K + + E + S G+ PA
Sbjct: 512 MGMGPLGKGAGPVPPGKVGPAT----PSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPA 567
Query: 2034 VSDEKNINTFVETPVQKLDLLGNLPGSKRQPQTPKEKAEALEDLVGFKELFQTPGHTEES 2093
EK++ ++ G P K P + KAE D + E
Sbjct: 568 --QEKSLGNILQAKPTSSPAKG--PPQKAGPVAVQVKAEKPMD----------NSESSEE 613
Query: 2094 MTDDKITEVSCKSPQPESFKTSRSSKQRLKIPLVKVDMKEEPLAVSKLTRTSGETTQ--- 2150
+D S S + + T+ +K LKIP K K+ S TQ
Sbjct: 614 SSD------SADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPR 667
Query: 2151 ---THTEPTGDSKSIKAFKESP------KQILDPAASVTGSRRQLRTRKEKARALEDLVD 2201
T T P G S ++ + P + D TG + K + L+
Sbjct: 668 KAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAA 727
Query: 2202 FKELFSA---------PGHTEESMTIDKNTKIPCKSPPPELTDT--ATSTKRCPKTRPRK 2250
+ + PG T ++T K K E +D+ A ++ KT +K
Sbjct: 728 SVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKK 787
Query: 2251 EVKEELSAVERLTQTSGQSTHTHKEPASGDEGIKVLKQRAKKKPNPVEEEPSRRRPRAPK 2310
+ A R G T P KQR+ K P P A
Sbjct: 788 TQAKANPAAARAPSAKG----TISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARG 843
Query: 2311 EKAQPLEDLAGFTELSETSGHTQESLTAGKATKIPCESPPLEVVDTTASTKRHLRT---R 2367
+ P A T +G ++S ++ + ES E +T A K +T R
Sbjct: 844 PASVPSVGKAVATAAQAQTGPEEDSGSSEE------ESDSEEEAETLAQVKPSGKTHQIR 897
Query: 2368 VQKVQVKEEPSAVKFTQTSGETTDADKEPAGEDKGIKALKESAKQTPAPAASVTGSRRRP 2427
KE P G+T + + +D + +ES APAA
Sbjct: 898 AALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVT------- 950
Query: 2428 RAPRESAQAIEDLAGFKDPAAGHTEESMTDDKTTKIPCKSSPELEDTATSSKRRPRTRAQ 2487
SAQ I+ F DP + T + S+P + S+ R + ++
Sbjct: 951 -----SAQVIKPPLIFVDPNRSPAGPAATP---AQAQAASTPRKARASESTARSSSSESE 1002
Query: 2488 KVEV--KEELLAVGKLTQT-SGETTHTDKEPVGEGKGTKAFKQPAK----RKLDAEDVIG 2540
+V + L G T + T H P G + K+ ++ +K +
Sbjct: 1003 DEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQV 1062
Query: 2541 SRRQPRAPKEKAQPLEDLASFQELSQTPGHTEELANGAADSFTSAPKQTPDSGKPLKISR 2600
S++ P + L+ LA +Q P + ++G + + P +P S
Sbjct: 1063 SKKNPASLPLTQAALKVLAQKASEAQPPVARTQPSSGVDSAVGTLPATSPQSTSVQAKGT 1122
Query: 2601 RVLRAPKVEPVGDVVSTRDPVKSQSKSNTSLPPLPFKRGGGKDG-SVTGTKRLRCM-PAP 2658
LR PK+ V +T+ P S ++S G +DG G K + P P
Sbjct: 1123 NKLRKPKLPEVQQ--ATKAPESSDDSEDSS----DSSSGSEEDGEGPQGAKSAHTLGPTP 1176
Query: 2659 ---EEIVEELPA--SKKQRVAPR---ARGKSSEPVVIMKRSLRTSAKRIEPAEELNS--- 2707
E +VEE A S+ VAP G + + + +++ + ++S
Sbjct: 1177 SRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLA 1236
Query: 2708 -NDMKTNKEEHKLQDSV----PENKG-------ISLRSRRQNK----------------- 2738
D K+E K Q + P+ G +SR+ K
Sbjct: 1237 AKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNIT 1296
Query: 2739 ----------TEAEQQITEVFVLAERIEINRNEKKPMKTSPEMDIQNPDDGARK-----P 2783
EA+ Q + V VL E +E R KK + T+ E + + RK P
Sbjct: 1297 QCLLGQPWPLNEAQVQASVVKVLTELLEQER--KKVVDTTKESSRKGWESRKRKLSGDQP 1354
Query: 2784 IPRDKVTENKRCLRSARQNES--SQPKVAEESGG---QKSAKVLMQNQKGKGEAGNSDSM 2838
R ++ K+ L + E+ S K + S G + A ++ +KGKG G+ +
Sbjct: 1355 AARTPRSKKKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAK 1414
Query: 2839 CLRSRKTKSQPAASTLES------KSVQRVTRSVKRCAENPKKAEDNVCVKKIRTRSHRD 2892
+ + Q T+E KS + +S KR + KK + KK + S +D
Sbjct: 1415 --DEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKK----KKAKKASTKD 1468
Query: 2893 SE 2894
SE
Sbjct: 1469 SE 1470
Score = 52.0 bits (123), Expect = 9e-06
Identities = 129/674 (19%), Positives = 239/674 (35%), Gaps = 126/674 (18%)
Query: 2230 PPELTDTATSTKRCPKTRPRKEVKEELSAVERLTQTSGQSTHTHKEPASGDEGIKVLKQR 2289
P L D T ++ + +++ +E+ + + T+ S + + S +E + +
Sbjct: 43 PVTLLDIYTHWQQTSELGRKRKAEEDAALQAKKTRVSDPISTSE----SSEEEEEAEAET 98
Query: 2290 AKKKPNPVEEEPS---RRRPRAPKEKAQPLEDLAGFTELS---ETSGHTQESLTAGKATK 2343
AK P S P + KEKA+ + AG T S +G T +L +GK+ +
Sbjct: 99 AKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPR 158
Query: 2344 IPCESPPLEVVDTTASTKRH-------LRTRVQKVQVKEEPSAVKFTQTSGETTDADKEP 2396
E P + T+ + V + S+ + T +S + TD + +P
Sbjct: 159 KSAE--PSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKP 216
Query: 2397 AGEDKGIKALKESAKQTPAPAASVTGSRRRPRAPRESAQAIEDLAGFKDPAAGHTEESMT 2456
+ + +KA S K++PA R+ AP + + G P A
Sbjct: 217 SVKPAQVKASSVSTKESPA--------RKAAPAPGKVGDVTPQVKGGALPPA-------- 260
Query: 2457 DDKTTKIPCKSSPELEDTATSSKRRPRTRAQKVEVKEELLAVGKLTQTSGETTHTDKEPV 2516
K K P + S E+ + S + P +V+ E++L V + + T P
Sbjct: 261 --KRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPA 318
Query: 2517 GEGKGTKAFKQPAKRKLDAEDVIGSRRQPRAPKEKAQPLEDLASFQELSQTPGHTEELAN 2576
GK + S+ + P+E ++
Sbjct: 319 PPGKA---------------GAVASQTKAGKPEEDSE----------------------- 340
Query: 2577 GAADSFTSAPKQTPDSGKPLKISRRVLRAPKVEPVGDVVSTRDPVKSQSKSNTSLPPLPF 2636
S+ +++ DS + ++ +L+A V + P K +S + P P
Sbjct: 341 -------SSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAK-ESPRKGAAPAPPG 392
Query: 2637 KRGGGKDGSVTGTKRLRCMPAPEE--IVEELPA-SKKQRVAPRARGKSSEPVVIMKRSLR 2693
K G + G + + EE EE PA +K AP+ R S+ K S R
Sbjct: 393 KTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAP----AKESPR 448
Query: 2694 TSAKRIEPAEELNSNDMKTNKEEHKLQDSVPENKGISLRSRRQNKTEAEQQITEVFVLAE 2753
A P KT ++Q + +++ +E+ ++ LA
Sbjct: 449 KGAAPAPP--------RKTGPAAAQVQVG---------KQEEDSRSSSEESDSDREALA- 490
Query: 2754 RIEINRNEKKPMKTSPEMDI-----QNPDDGARKPIPRDKV---TENKRCLRSARQNESS 2805
+N + KP+ SP++ P P+P KV T + + + +ESS
Sbjct: 491 --AMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESS 548
Query: 2806 QPKVAEESGGQKSAKVLMQNQKGKGEAGNSDSMCLRSRKTKSQPAASTLESKSVQRVTRS 2865
+ ++ S G+ V +K G + K S PA + V
Sbjct: 549 SEESSDSSDGEVPTAVAPAQEKSLGN--------ILQAKPTSSPAKGPPQKAGPVAVQVK 600
Query: 2866 VKRCAENPKKAEDN 2879
++ +N + +E++
Sbjct: 601 AEKPMDNSESSEES 614
>gi|52426735 ankyrin 2 isoform 1 [Homo sapiens]
Length = 3957
Score = 65.5 bits (158), Expect = 7e-10
Identities = 314/1536 (20%), Positives = 534/1536 (34%), Gaps = 276/1536 (17%)
Query: 496 TKTSDTETEPSKTVSTANRSGRSTEFRN--------IQKLPVESKSEETN--TEIVECIL 545
TK S+++ E + + + TE + ++PV + + + +E+ + ++
Sbjct: 1456 TKESESDQEQEEEIDMTSEKNDETESTETSVLKSHLVNEVPVLASPDLLSEVSEMKQDLI 1515
Query: 546 KRGQKATLLQQRREG--EMKEI-----ERPFETYKENIELKENDEKMKAMKRSRTWGQKC 598
K T + G ++KE+ E P E ++ +KE+ EK+ + RS T +
Sbjct: 1516 KMTAILTTDVSDKAGSIKVKELVKAAEEEPGEPFEIVERVKEDLEKVNEILRSGTCTRDE 1575
Query: 599 APMSDLTDLKSLPDTELMK------DTARGQNLLQTQDH----AKAPKSEKGKITKMPCQ 648
+ + + L + E + + AR + L+ ++ + K KGK+ K
Sbjct: 1576 SSVQSSRSERGLVEEEWVIVSDEEIEEARQKAPLEITEYPCVEVRIDKEIKGKVEKDSTG 1635
Query: 649 SLQ--PEPINTPTHT-KQQLKASLGKVGVKEELLAVGKFTRTSGE---------TTHTHR 696
+ + +NT K+QL+ K G K E LAVG+ + G+ T H+
Sbjct: 1636 LVNYLTDDLNTCVPLPKEQLQTVQDKAGKKCEALAVGRSSEKEGKDIPPDETQSTQKQHK 1695
Query: 697 EPAGDGKSI-RTFKESPKQILDPAARVTGMKKWPRTPKEEAQSLEDLAGFKELFQTPGPS 755
G K + R KE KQ K+ E L+ + + L + PG +
Sbjct: 1696 PSLGIKKPVRRKLKEKQKQ-----------KEEGLQASAEKAELKKGSSEESLGEDPGLA 1744
Query: 756 EESMTDEKTTKIACKSPPPESVDTPTSTKQWPKRSLRKADVEEEFLALRKL-------TP 808
E + K T P +TP + + ++L+K VE+E KL
Sbjct: 1745 PEPLPTVKATS-------PLIEETPIGSIKDKVKALQKR-VEDEQKGRSKLPIRVKGKED 1796
Query: 809 SAGKAMLTPKPAGGDE-KDIKAFMGTPVQKLDLAGTLPGS-KRQLQTPKEKAQALEDLAG 866
K P PA K + G+P K + TL S K + P + E +
Sbjct: 1797 VPKKTTHRPHPAASPSLKSERHAPGSPSPKTERHSTLSSSAKTERHPPVSPSSKTEKHSP 1856
Query: 867 FKELFQTPGH--------TEELVAAGKTTKIPCDSPQSD-------PVDTPTSTKQRPK- 910
+T H TE+ +TK SP S PV T +RP
Sbjct: 1857 VSPSAKTERHSPASSSSKTEKHSPVSPSTKTERHSPVSSTKTERHPPVSPSGKTDKRPPV 1916
Query: 911 ----RSIRKADVE-GELLACRNLMPSAGKAMHTPKPSVGE-EKDIIIFVGTPVQKLDLTE 964
R+ + V G + PS H P + G+ EK + PV TE
Sbjct: 1917 SPSGRTEKHPPVSPGRTEKRLPVSPSGRTDKHQPVSTAGKTEKHL------PVSPSGKTE 1970
Query: 965 NLTGSKRRPQTPKEEAQALEDLTGFKELF------QTPGHTEEAVAAGKTTKMPCESSPP 1018
K+ P +P + + +E+ +EL Q P + + K+ K + P
Sbjct: 1971 -----KQPPVSPTSKTERIEETMSVRELMKAFQSGQDPSKHKTGLFEHKSAK---QKQPQ 2022
Query: 1019 ESADTPTSTRRQPKTPLEKRDVQKELSALKKLTQTSGETTHTDKVPGGEDKSINAFRETA 1078
E + P L +R+ QK + K Q T + G SI +E A
Sbjct: 2023 EKGKVRVEKEKGP--ILTQREAQKTENQTIKRGQRLPVTGTAESKRGVRVSSIGVKKEDA 2080
Query: 1079 ---KQKL------DPAASVTGSKRHPKTKEKAQPLEDLAGLKELFQTPVCTDKPTTHEKT 1129
K+K+ +P SV + H +++ + + D G +L +P D+ T+ + +
Sbjct: 2081 AGGKEKVLSHKIPEPVQSVPEEESHRESEVPKEKMADEQGDMDLQISP---DRKTSTDFS 2137
Query: 1130 TKIACRSQPDPVDTPTSSKPQSKRSLRKVD---------------VEEEFFALRKRTPSA 1174
I + + +++++ +D +++EF A
Sbjct: 2138 EVIKQELEDNDKYQQFRLSEETEKAQLHLDQVLTSPFNTTFPLDYMKDEFLPALSLQSGA 2197
Query: 1175 --GKAMHTPKPAVSGEKNIYAFMGTPVQKLDLTENLTGSKRRLQTPKEKAQALEDLAGFK 1232
G + V+G GTP +E + +TP+ ++L K
Sbjct: 2198 LDGSSESLKNEGVAGSPCGSLMEGTPQIS---SEESYKHEGLAETPETSPESLS--FSPK 2252
Query: 1233 ELFQTRGHTEESMTNDKTAKVACKSSQPDPDKNPASSKRRLKTSLGKVGVKEELLAVGKL 1292
+ + G T+ES + T ++ + P S+ R T E
Sbjct: 2253 KSEEQTGETKESTKTETTTEIRSEKEHPTTKDITGGSEERGATVTEDSETSTESFQKEAT 2312
Query: 1293 TQTSGETTHTHTEPTGDGKSMKAFMESPKQILDSAASLTGSKRQLRTPKGKSEVPEDLAG 1352
+ +T+ + S+ E+P + + AA G +R + K+
Sbjct: 2313 LGSPKDTSPKRQDDCTGSCSVALAKETPTGLTEEAACDEG-QRTFGSSAHKT-------- 2363
Query: 1353 FIELFQTPSHTKESMTNEKTTKVSYRASQPDLVDTPTSSKPQ-------------PKR-- 1397
QT S +ES TK DT T SKPQ P R
Sbjct: 2364 -----QTDSEVQESTATSDETKALPLPEASVKTDTGTESKPQGVIRSPQGLELALPSRDS 2418
Query: 1398 SLRKADTEEEFLAFRKQTPSAGKAMH------TP---KPAVGEEKDINTFL-GTPVQKLD 1447
+ A ++ K + A + TP +P+ +E L +PV+
Sbjct: 2419 EVLSAVADDSLAVSHKDSLEASPVLEDNSSHKTPDSLEPSPLKESPCRDSLESSPVEPKM 2478
Query: 1448 QPGNLPGSNRRLQTRKEKAQALEELTGFR-ELFQTPCTDNPTTDEKTTKKILCKSPQSDP 1506
+ G P S+ L K + L E+ R L + P D D+ + L +S P
Sbjct: 2479 KAGIFP-SHFPLPAAVAKTELLTEVASVRSRLLRDP--DGSAEDDSLEQTSLMESSGKSP 2535
Query: 1507 --ADTPTNTKQRPKRSLKKADVEEEFLAFRKLTPSAGKAMHTPKAAV----GEEKDINTF 1560
DTP++ + + + K DV TPK AV EE D
Sbjct: 2536 LSPDTPSSEEVSYEVTPKTTDVS------------------TPKPAVIHECAEEDDSEN- 2576
Query: 1561 VGTPVEKLDLLGNLPGSKRRPQTPKEKAKALEDLAGFKELFQ----------TPGHTEES 1610
G K+R +E K + + F EL Q P E S
Sbjct: 2577 ---------------GEKKRFTPEEEMFKMVTKIKMFDELEQEAKQKRDYKKEPKQEESS 2621
Query: 1611 MTDDKITEVSCKSPQPD-----------PV-------KTPTSSKQRLKISLGKVGVKEEV 1652
+ D + S +P PV K +SS+ +++ K G +
Sbjct: 2622 SSSDPDADCSVDVDEPKHTGSGEDESGVPVLVTSESRKVSSSSESEPELAQLKKGADSGL 2681
Query: 1653 LPVGKLTQTSGKTTQTHRETAGDGKSIKAFKESAKQMLDPANYGTGMERWPRTPKEEAQS 1712
LP + + ++ + ++ +KQ N T E P +EE S
Sbjct: 2682 LPEPVIRVQPPSPLPSSMDSNSSPEEVQFQPVVSKQYTFKMNEDTQEE--PGKSEEEKDS 2739
Query: 1713 LEDLAGFKELFQTPDHT---EESTTDDKTTKI----ACKSPPPESMDTPTSTRRRPKTPL 1765
LA + T ++ D KI C++ P S P S+ ++P
Sbjct: 2740 ESHLAEDRHAVSTEAEDRSYDKLNRDTDQPKICDGHGCEAMSPSSSAAPVSSGL--QSPT 2797
Query: 1766 GKRDIVEELSALKQ--LTQTTHTDKVPGDEDKGINVFRETAKQKLDPAASVTGSKRQPRT 1823
G D+ E+ K+ Q TH G+E ++V R + Q P+ S + S P
Sbjct: 2798 GD-DVDEQPVIYKESLALQGTHEKDTEGEE---LDVSRAESPQADCPSESFSSSSSLPHC 2853
Query: 1824 PKGKAQPL-EDLAGLKELFQTPICTDKPTTHEKTTK 1858
+ + L ED++ + +T + T T E K
Sbjct: 2854 LVSEGKELDEDISATSSIQKTEV-TKTDETFENLPK 2888
Score = 47.8 bits (112), Expect = 2e-04
Identities = 201/995 (20%), Positives = 334/995 (33%), Gaps = 213/995 (21%)
Query: 1966 PGTDKPTTDEKTTKIACKSPQPDPVDTPASTKQR-----PKRNLRKADVEEEFLALRKRT 2020
PG+ P T+ +T + + P +P+S ++ P + K +
Sbjct: 1820 PGSPSPKTERHSTLSSSAKTERHPPVSPSSKTEKHSPVSPSAKTERHSPASSSSKTEKHS 1879
Query: 2021 PSAGKAMDTPKPAVSDEKNINTFVETPVQKLDLLGNLPGSKRQPQTPKEKAEALEDLVGF 2080
P + VS K +P K D KR P +P + E
Sbjct: 1880 PVSPSTKTERHSPVSSTKTERHPPVSPSGKTD--------KRPPVSPSGRTE-------- 1923
Query: 2081 KELFQTPGHTEESMT------DDKITEVSCKSPQPESFKTSRSSKQRLKIPLV---KVDM 2131
K +PG TE+ + DK VS + S S K + P+ K +
Sbjct: 1924 KHPPVSPGRTEKRLPVSPSGRTDKHQPVSTAGKTEKHLPVSPSGKTEKQPPVSPTSKTER 1983
Query: 2132 KEEPLAVSKLTRT--SGETTQTHTEPTGDSKSIKAFKESPKQILDPAASVTGSRRQLRTR 2189
EE ++V +L + SG+ H + KS K ++ P++ + ++R
Sbjct: 1984 IEETMSVRELMKAFQSGQDPSKHKTGLFEHKSAK--QKQPQE-----------KGKVRVE 2030
Query: 2190 KEKARALEDLVDFKELFSAPGHTEESMTIDKNTKIPCKSPPPELTDTATSTKRCPKTRPR 2249
KEK L E+ TI + ++P +T TA S
Sbjct: 2031 KEKGPILTQ---------REAQKTENQTIKRGQRLP-------VTGTAES---------- 2064
Query: 2250 KEVKEELSAVERLTQTSGQSTHTHKEPASGDEGIKVLKQRAKKKPNPVEEEPSRRRPRAP 2309
+R + S S KE A+G + KVL + + V EE S R P
Sbjct: 2065 ----------KRGVRVS--SIGVKKEDAAGGKE-KVLSHKIPEPVQSVPEEESHRESEVP 2111
Query: 2310 KEK--------------------------AQPLEDLAGFTE--LSETSG----HTQESLT 2337
KEK Q LED + + LSE + H + LT
Sbjct: 2112 KEKMADEQGDMDLQISPDRKTSTDFSEVIKQELEDNDKYQQFRLSEETEKAQLHLDQVLT 2171
Query: 2338 AGKATKIPCESPPLEVVDTTASTKRHLRTRVQKVQ---VKEEPSAVKFTQTSGETTDADK 2394
+ T P + E + + L + ++ V P T +++
Sbjct: 2172 SPFNTTFPLDYMKDEFLPALSLQSGALDGSSESLKNEGVAGSPCGSLMEGTPQISSEESY 2231
Query: 2395 EPAGEDKGIKALKESAKQTPAPAASVTGSRRRP---------RAPRESAQAIEDLAGFKD 2445
+ G + + ES +P + TG + R+ +E + G ++
Sbjct: 2232 KHEGLAETPETSPESLSFSPKKSEEQTGETKESTKTETTTEIRSEKEHPTTKDITGGSEE 2291
Query: 2446 PAAGHTEESMTD------DKTTKIPCKSSPELEDTATSS------KRRPRTRAQKVEVKE 2493
A TE+S T + T P +SP+ +D T S K P ++ E
Sbjct: 2292 RGATVTEDSETSTESFQKEATLGSPKDTSPKRQDDCTGSCSVALAKETPTGLTEEAACDE 2351
Query: 2494 ELLAVGKLTQTSGETTHTD---KEPVGEGKGTKAFKQP-AKRKLDAEDVIGSRRQPRAPK 2549
G +S T TD +E TKA P A K D G+ +P+
Sbjct: 2352 GQRTFG----SSAHKTQTDSEVQESTATSDETKALPLPEASVKTDT----GTESKPQGVI 2403
Query: 2550 EKAQPLE-DLASFQELSQTPGHTEELANGAADSFTSAP-------KQTPDSGKPLKISRR 2601
Q LE L S + + LA DS ++P +TPDS +P +
Sbjct: 2404 RSPQGLELALPSRDSEVLSAVADDSLAVSHKDSLEASPVLEDNSSHKTPDSLEPSPL--- 2460
Query: 2602 VLRAPKVEPVGDVVSTRDPVKSQSKSNTSLPPLPFKRGGGKDGSVT--GTKRLRCMPAPE 2659
K P D + + PV+ + K+ P K +T + R R + P+
Sbjct: 2461 -----KESPCRDSLES-SPVEPKMKAGIFPSHFPLPAAVAKTELLTEVASVRSRLLRDPD 2514
Query: 2660 EIVEE--------LPASKKQRVAPRARGKSSEPVVIMKRSLRTSAKRIEPAEELNSNDMK 2711
E+ + +S K ++P + ++ S + E D
Sbjct: 2515 GSAEDDSLEQTSLMESSGKSPLSPDTPSSEEVSYEVTPKTTDVSTPKPAVIHECAEEDDS 2574
Query: 2712 TNKEEHKLQDSVPENKGISLRSRRQNKTEAEQQITEVFVLAERIEINRNEKKPMKTSPEM 2771
N E+ + PE + + ++ + E EQ+ + R+ KK K
Sbjct: 2575 ENGEKKRF---TPEEEMFKMVTKIKMFDELEQEAKQ----------KRDYKKEPKQEESS 2621
Query: 2772 DIQNPDDGARKPIPRDKVTENKRCLRSARQNESSQPKVA-----EESGGQKSAKVLMQNQ 2826
+PD + K T + ++ES P + + S +S L Q +
Sbjct: 2622 SSSDPDADCSVDVDEPKHT-------GSGEDESGVPVLVTSESRKVSSSSESEPELAQLK 2674
Query: 2827 KGKGEAGNSDSMCLRSRKTKSQPAA---STLESKS 2858
KG +DS L + QP + S+++S S
Sbjct: 2675 KG------ADSGLLPEPVIRVQPPSPLPSSMDSNS 2703
Score = 44.3 bits (103), Expect = 0.002
Identities = 241/1251 (19%), Positives = 418/1251 (33%), Gaps = 199/1251 (15%)
Query: 1706 PKEEAQSLEDLAGFKELFQTPDHTEESTTDDKTTKIACKSPPPESMDTPTSTRRRPKTPL 1765
PKE+ Q+++D AG K E+ ++++ K PP D ST+++ K L
Sbjct: 1651 PKEQLQTVQDKAGKKC---------EALAVGRSSEKEGKDIPP---DETQSTQKQHKPSL 1698
Query: 1766 GKRDIVEELSALKQLTQTTHTDKVPGDEDKGINVFRETAKQKLDPAASVTGSKRQPRTPK 1825
G + V KQ +++G+ E A+ K + G P
Sbjct: 1699 GIKKPVRRKLKEKQK-----------QKEEGLQASAEKAELKKGSSEESLGED-----PG 1742
Query: 1826 GKAQPLEDLAGLKELFQ-TPICT--DKPTTHEKT--------TKIACRSPQPDPVGTPTI 1874
+PL + L + TPI + DK +K +K+ R + V T
Sbjct: 1743 LAPEPLPTVKATSPLIEETPIGSIKDKVKALQKRVEDEQKGRSKLPIRVKGKEDVPKKTT 1802
Query: 1875 FKPQ-----SKRSLRKADVEEESLALRKRTPSVGKAMDTPKPAGGDEKDMKAFMGTPVQK 1929
+P S +S R A R T S + P K K +P K
Sbjct: 1803 HRPHPAASPSLKSERHAPGSPSPKTERHSTLSSSAKTERHPPVSPSSKTEKHSPVSPSAK 1862
Query: 1930 LDLPGNLPGS----KRWPQTPKEKAQALEDLAGFKELFQTPGTDKPTTDEKTTKIACKSP 1985
+ S K P +P K + ++ K P + TD++
Sbjct: 1863 TERHSPASSSSKTEKHSPVSPSTKTERHSPVSSTKTERHPPVSPSGKTDKRP-------- 1914
Query: 1986 QPDPVDTPASTKQRPKRNLRKADVEEEFLALRKRTP-SAGKAMDTPKPAVSDEKNINTFV 2044
PV T++ P + + + KR P S D +P + K
Sbjct: 1915 ---PVSPSGRTEKHPPVSPGRTE---------KRLPVSPSGRTDKHQPVSTAGKTEKHLP 1962
Query: 2045 ETPVQKLDLLGNLPGSKRQPQTPKEKAEALEDLVGFKELF------QTPGHTEESMTDDK 2098
+P K + K+ P +P K E +E+ + +EL Q P + + + K
Sbjct: 1963 VSPSGKTE--------KQPPVSPTSKTERIEETMSVRELMKAFQSGQDPSKHKTGLFEHK 2014
Query: 2099 ITEVSCKSPQPESFKTSRSSKQRLKIPLVKVDMKEEPLAVSK-----LTRTSGETTQTHT 2153
S K QP+ R K++ I + K E + + +T T+
Sbjct: 2015 ----SAKQKQPQEKGKVRVEKEKGPILTQREAQKTENQTIKRGQRLPVTGTAESKRGVRV 2070
Query: 2154 EPTGDSKSIKAF---KESPKQILDPAASVTG--SRRQLRTRKEKARALEDLVDFKELFSA 2208
G K A K +I +P SV S R+ KEK + +D +
Sbjct: 2071 SSIGVKKEDAAGGKEKVLSHKIPEPVQSVPEEESHRESEVPKEKMADEQGDMDLQISPDR 2130
Query: 2209 PGHTEESMTIDKNTKIPCKSPPPELTDTATS---------TKRCPKTRPRKEVKEELSAV 2259
T+ S I + + K L++ T T P +K+E
Sbjct: 2131 KTSTDFSEVIKQELEDNDKYQQFRLSEETEKAQLHLDQVLTSPFNTTFPLDYMKDEFLPA 2190
Query: 2260 ERLTQTS--GQSTHTHKEPASGDEGIKVLKQRAKKKPNPVEEEPSRRRPRAPKEKAQPLE 2317
L + G S E +G +++ P EE + A + P
Sbjct: 2191 LSLQSGALDGSSESLKNEGVAGSPCGSLMEGT----PQISSEESYKHEGLAETPETSPES 2246
Query: 2318 DLAGFTELSETSGHTQESLTAGKATKIPCESPPLEVVDTTASTKRHLRTRVQKVQVKEEP 2377
+ E +G T+ES T+I E D T ++ T V E
Sbjct: 2247 LSFSPKKSEEQTGETKESTKTETTTEIRSEKEHPTTKDITGGSEERGAT----VTEDSET 2302
Query: 2378 SAVKFTQTSGETTDADKEPAGEDKGIKALKES-AKQTPAPAASVTGSRRRPRAPRESAQA 2436
S F + + + D P +D + + AK+TP R SA
Sbjct: 2303 STESFQKEATLGSPKDTSPKRQDDCTGSCSVALAKETPTGLTEEAACDEGQRTFGSSAHK 2362
Query: 2437 IEDLAGFKDPAAGHTEESMTDDKTTKIPCKSSPELEDTATSSKRRPRTRA-QKVEV---K 2492
+ + ++ A T D+T +P + DT T SK + R+ Q +E+
Sbjct: 2363 TQTDSEVQESTA-------TSDETKALPLPEASVKTDTGTESKPQGVIRSPQGLELALPS 2415
Query: 2493 EELLAVGKLTQTSGETTHTDKEPVGEGKGTKAFKQPAKRKLDAEDVIGSRRQPRAPKE-K 2551
+ + + S +H D L+A V+ + P +
Sbjct: 2416 RDSEVLSAVADDSLAVSHKD-------------------SLEASPVLEDNSSHKTPDSLE 2456
Query: 2552 AQPLEDLASFQELSQTPGHTEELANGAADSF--TSAPKQTPDSGKPLKISRRVLRAPKVE 2609
PL++ L +P + A F +A +T + + R+LR P
Sbjct: 2457 PSPLKESPCRDSLESSPVEPKMKAGIFPSHFPLPAAVAKTELLTEVASVRSRLLRDPDGS 2516
Query: 2610 PVGDVVSTRDPVKSQSKSNTSLPPLPFKRGGGKDGSVTGTKRLRCMPAPEEIV------- 2662
D + ++S KS PL ++ S T + + P+ V
Sbjct: 2517 AEDDSLEQTSLMESSGKS-----PLSPDTPSSEEVSYEVTPKTTDVSTPKPAVIHECAEE 2571
Query: 2663 EELPASKKQRVAPRARGKSSEPVVIMKRSLRTSAK-----RIEPAEELNSN------DMK 2711
++ +K+R P + M L AK + EP +E +S+ D
Sbjct: 2572 DDSENGEKKRFTPEEEMFKMVTKIKMFDELEQEAKQKRDYKKEPKQEESSSSSDPDADCS 2631
Query: 2712 TNKEEHKLQDSVPENKGISLRSRRQNKTEAEQQITEVFVLAERIEINRNEKKPMKTSPEM 2771
+ +E K S + G+ + +++ + +E E ++ + + P +
Sbjct: 2632 VDVDEPKHTGSGEDESGVPVLVTSESRKVSSSSESE----PELAQLKKGADSGLLPEPVI 2687
Query: 2772 DIQNPDDGARKPIPRDKVTENKRCLRSARQNESSQPKVAEESGGQKSAKVLMQNQKGKGE 2831
+Q P P+P + S+ + QP V+++ + + Q + GK E
Sbjct: 2688 RVQPP-----SPLPSSMDS------NSSPEEVQFQPVVSKQYTFKMNEDT--QEEPGKSE 2734
Query: 2832 AGNSDSMCLRSRKTKSQPAAST-LESKSVQRVTRSVKRCAENPKKAEDNVC 2881
DS S + + A ST E +S ++ R + PK + + C
Sbjct: 2735 E-EKDS---ESHLAEDRHAVSTEAEDRSYDKLNRD----TDQPKICDGHGC 2777
Score = 38.1 bits (87), Expect = 0.13
Identities = 363/1867 (19%), Positives = 657/1867 (35%), Gaps = 309/1867 (16%)
Query: 1212 KRRL-QTPKEKAQALEDLAGFKELFQTRGHTEESMTNDKTAKV----ACKSSQPDPDKNP 1266
+R+L + K+K + L+ A EL +G +EES+ D K++ P ++ P
Sbjct: 1705 RRKLKEKQKQKEEGLQASAEKAEL--KKGSSEESLGEDPGLAPEPLPTVKATSPLIEETP 1762
Query: 1267 ASSKRRLKTSLGKVGVKEELLAVGKLT-------QTSGETTHT-HTEPTGDGKSMKAFME 1318
S + +L K V++E KL +TTH H + KS +
Sbjct: 1763 IGSIKDKVKALQK-RVEDEQKGRSKLPIRVKGKEDVPKKTTHRPHPAASPSLKSERHAPG 1821
Query: 1319 SPKQILDSAASLTGS-KRQLRTPKGKSEVPEDLAGFIELFQTPSHTKESMTN--EKTTKV 1375
SP + ++L+ S K + P S E + +T H+ S ++ EK + V
Sbjct: 1822 SPSPKTERHSTLSSSAKTERHPPVSPSSKTEKHSPVSPSAKTERHSPASSSSKTEKHSPV 1881
Query: 1376 S--YRASQPDLVDTPTSSKPQPKRSLRKADTEEEFLAFRKQTPSAGKAMHTPKPAVGEEK 1433
S + + V + + + P K D +PS H P EK
Sbjct: 1882 SPSTKTERHSPVSSTKTERHPPVSPSGKTDKRPPV------SPSGRTEKHPPVSPGRTEK 1935
Query: 1434 DINTFLGTPVQKLD--QPGNLPGSNRRL-------QTRKE-------KAQALEELTGFRE 1477
+ +P + D QP + G + +T K+ K + +EE RE
Sbjct: 1936 RLPV---SPSGRTDKHQPVSTAGKTEKHLPVSPSGKTEKQPPVSPTSKTERIEETMSVRE 1992
Query: 1478 LFQTPCTDNPTTDEKTT----KKILCKSPQSDPADTPTNTKQRPKRSLKKAD-VEEEFLA 1532
L + + + KT K K PQ + ++ P + ++A E + +
Sbjct: 1993 LMKAFQSGQDPSKHKTGLFEHKSAKQKQPQ-EKGKVRVEKEKGPILTQREAQKTENQTIK 2051
Query: 1533 FRKLTPSAGKA------------MHTPKAAVGEEKDINTFVGTPVEKLDLLGNLPGSKRR 1580
+ P G A + AA G+EK ++ + PV+ + S R
Sbjct: 2052 RGQRLPVTGTAESKRGVRVSSIGVKKEDAAGGKEKVLSHKIPEPVQSVPE----EESHRE 2107
Query: 1581 PQTPKEKAKALEDLAGFKELFQTPGHTEESMTDDKITEVSCKSPQPDPVKTPTSSKQRLK 1640
+ PKEK + D G +L +P + + I + + + + + ++ +
Sbjct: 2108 SEVPKEK---MADEQGDMDLQISPDRKTSTDFSEVIKQELEDNDKYQQFRL-SEETEKAQ 2163
Query: 1641 ISLGKV------------GVKEEVLPVGKLTQTSGK---TTQTHRETAGDGKSIKAFKES 1685
+ L +V +K+E LP L+ SG ++++ + G + E
Sbjct: 2164 LHLDQVLTSPFNTTFPLDYMKDEFLPA--LSLQSGALDGSSESLKNEGVAGSPCGSLMEG 2221
Query: 1686 AKQMLDPANYGTGMERWPRTPKEEAQSLEDLAGFKELFQTPDHTEESTTDDKTTKIACKS 1745
Q+ +Y E TP+ +SL K+ + T+EST + TT+I +
Sbjct: 2222 TPQISSEESYKH--EGLAETPETSPESLSFSP--KKSEEQTGETKESTKTETTTEIRSEK 2277
Query: 1746 PPPESMDTPTSTRRRPKTPLGKRDIVEELSALKQLTQTTHTDKVPGDEDK-----GINVF 1800
P + D + R T + E S K+ T + D P +D + +
Sbjct: 2278 EHPTTKDITGGSEERGATVTEDSETSTE-SFQKEATLGSPKDTSPKRQDDCTGSCSVALA 2336
Query: 1801 RETAKQKLDPAASVTGS--------KRQPRTPKGKAQPLEDLAGLKELFQTPICTDKPTT 1852
+ET + AA G K Q + ++ D L + + TD T
Sbjct: 2337 KETPTGLTEEAACDEGQRTFGSSAHKTQTDSEVQESTATSDETKALPLPEASVKTDTGT- 2395
Query: 1853 HEKTTKIACRSPQPDPVGTPTIFKPQSKRSLRKADVEEESLALRKRTP----------SV 1902
E + RSPQ + P S+ S + V ++SLA+ + S
Sbjct: 2396 -ESKPQGVIRSPQGLELALP------SRDSEVLSAVADDSLAVSHKDSLEASPVLEDNSS 2448
Query: 1903 GKAMDTPKPAGGDEKDMK-AFMGTPVQKLDLPGNLPGSKRWPQTPKEKAQALEDLAGFK- 1960
K D+ +P+ E + + +PV+ G P P K + L ++A +
Sbjct: 2449 HKTPDSLEPSPLKESPCRDSLESSPVEPKMKAGIFPSHFPLP-AAVAKTELLTEVASVRS 2507
Query: 1961 ELFQTP-GTDKPTTDEKTTKIACKSPQPDPVDTPASTKQRPKRNLRKADVEEEFLALRKR 2019
L + P G+ + + E+T+ + P DTP+S + + + DV
Sbjct: 2508 RLLRDPDGSAEDDSLEQTSLMESSGKSPLSPDTPSSEEVSYEVTPKTTDV---------- 2557
Query: 2020 TPSAGKAMDTPKPAV-------SDEKNINTFVETPVQKL-DLLGNLPGSKRQPQTPKEKA 2071
TPKPAV D +N TP +++ ++ + Q K+K
Sbjct: 2558 --------STPKPAVIHECAEEDDSENGEKKRFTPEEEMFKMVTKIKMFDELEQEAKQK- 2608
Query: 2072 EALEDLVGFKELFQTPGHTEESMTDDKITEVSCKSPQPESFKTSRSSKQRLKIPL----- 2126
++ + P E S + D + S +P K + S + +P+
Sbjct: 2609 ---------RDYKKEPKQEESSSSSDPDADCSVDVDEP---KHTGSGEDESGVPVLVTSE 2656
Query: 2127 ---VKVDMKEEP-LAVSKLTRTSGETTQ--THTEPTGDSKSIKAFKESPKQI-LDPAASV 2179
V + EP LA K SG + +P S SP+++ P S
Sbjct: 2657 SRKVSSSSESEPELAQLKKGADSGLLPEPVIRVQPPSPLPSSMDSNSSPEEVQFQPVVSK 2716
Query: 2180 TGSRRQLRTRKEKARALEDLVDFKELFSAPGHTEESMTIDKN-TKIPCKSPPPELTD--- 2235
+ + +E+ E+ D + + H + D++ K+ + P++ D
Sbjct: 2717 QYTFKMNEDTQEEPGKSEEEKDSESHLAEDRHAVSTEAEDRSYDKLNRDTDQPKICDGHG 2776
Query: 2236 ----TATSTKRCPKTRPRKEVKEELSAVERLTQTSGQSTHTHKEPASGDEGIKVLKQRAK 2291
+ +S+ + + +++ + + S TH++ G+E + V + +
Sbjct: 2777 CEAMSPSSSAAPVSSGLQSPTGDDVDEQPVIYKESLALQGTHEKDTEGEE-LDVSRAESP 2835
Query: 2292 KKPNPVEE-EPSRRRPRAPKEKAQPLEDLAGFTELSETSGHTQESLTAGKAT--KIPCES 2348
+ P E S P + + L++ ++S TS + +T T +P +
Sbjct: 2836 QADCPSESFSSSSSLPHCLVSEGKELDE-----DISATSSIQKTEVTKTDETFENLPKDC 2890
Query: 2349 PPLEVVDTTASTKRHLRTRVQKVQVKEE-------------PSAVKFTQTSGET-TDADK 2394
P + TT + + + V + +E PS F+ +T TDA+
Sbjct: 2891 PSQDSSITTQTDRFSMDVPVSDLAENDEIYDPQITSPYENVPSQSFFSSEESKTQTDANH 2950
Query: 2395 EPAGEDKGIKALK-ESAKQTPAPAASVTG------SRRRPRAPRESAQAIEDLAGFKDPA 2447
+ + ++ S + A+S +G S + + +Q L + +
Sbjct: 2951 TTSFHSSEVYSVTITSPVEDVVVASSSSGTVLSKESNFEGQDIKMESQQESTLWEMQSDS 3010
Query: 2448 AGHTEESMTDDKTTKIPCKSSPEL-----EDTATSSKRRPRTRAQKVEVKEEL-----LA 2497
+ E TT + + S + D+ + S+ R A + VKEE L
Sbjct: 3011 VSSSFEPTMSATTTVVGEQISKVIITKTDVDSDSWSEIREDDEAFEARVKEEEQKIFGLM 3070
Query: 2498 VGKLTQTSGETTHTDKEPVGEGKGT-----------KAFKQPAKRKLD------------ 2534
V + +Q + T + P EG T K F+ +D
Sbjct: 3071 VDRQSQGTTPDTTPARTPTEEGTPTSEQNPFLFQEGKLFEMTRSGAIDMTKRSYADESFH 3130
Query: 2535 --------AEDVIGSRRQPRAPKEKAQPLEDLASFQELSQTPGHTEELANGAADSFTSAP 2586
E+ + + A PLE A LS++ ++ A+ D +
Sbjct: 3131 FFQIGQESREETLSEDVKEGATGADPLPLETSAESLALSESKETVDDEADLLPDDVSEEV 3190
Query: 2587 KQTPDSGKPLKISRRVLRAPKVEPVGDVVS--TRDPVKSQSKSNTSLPPLPFKRGGGKDG 2644
++ P S L S+ + A P + VS T+D Q+ +PPL
Sbjct: 3191 EEIPASDAQLN-SQMGISASTETPTKEAVSVGTKDLPTVQT---GDIPPL---------- 3236
Query: 2645 SVTGTKRLRCMPAPEEIVE-ELPASKKQRVAPRARGKSSEPVVIMKRSLRTSAKRIEPAE 2703
+G K++ C + E V+ +L S R RG S P + P E
Sbjct: 3237 --SGVKQISCPDSSEPAVQVQLDFSTLTRSVYSDRGDDS-PDSSPEEQKSVIEIPTAPME 3293
Query: 2704 ELNSNDMKTNKEEHKLQDSVPENKGISLRSRRQNKTEAEQQITEVFVLAERIEINRNEKK 2763
+ + K+ + S P E E ++E F+ + E +E K
Sbjct: 3294 NVPFTESKSKIPVRTMPTSTP----------APPSAEYESSVSEDFLSSVDEENKADEAK 3343
Query: 2764 PMKTSPEMDIQNPDDGARKPIPRDKVTENKRCLRSARQNESSQPKVAEESGGQKSAKVLM 2823
P P +P +V + L + S Q VA + GQ A +
Sbjct: 3344 PKSKLP------------VKVPLQRVEQQLSDL-----DTSVQKTVAPQ--GQDMASIAP 3384
Query: 2824 QNQ-KGKGEAGNSDSMCLRSRKTKSQPAASTLESKSVQRVTRSVKRCAENPKKAEDNVCV 2882
N+ K + +A + DS KT+S T + + + + A PK + V
Sbjct: 3385 DNRSKSESDASSLDSKTKCPVKTRSYTETETESRERAEELELESEEGATRPKILTSRLPV 3444
Query: 2883 KKIRTRS 2889
K T S
Sbjct: 3445 KSRSTTS 3451
Score = 37.7 bits (86), Expect = 0.17
Identities = 102/500 (20%), Positives = 173/500 (34%), Gaps = 76/500 (15%)
Query: 2430 PRESAQAIEDLAGFKDPAAGHTEESMTDDKTTKIPCKSSPELEDTATSSKRRPRTRAQKV 2489
P+E Q ++D AG K A S + K S + + + ++P R K
Sbjct: 1651 PKEQLQTVQDKAGKKCEALAVGRSSEKEGKDIPPDETQSTQKQHKPSLGIKKPVRRKLKE 1710
Query: 2490 EVKEELLAVGKLTQTSGETTHTDKEPVGEGKGTKAFKQP---AKRKLDAEDVIGSRR--- 2543
+ K++ + + + + +E +GE G P A L E IGS +
Sbjct: 1711 KQKQKEEGLQASAEKAELKKGSSEESLGEDPGLAPEPLPTVKATSPLIEETPIGSIKDKV 1770
Query: 2544 ---QPRAPKEKAQPLEDLASFQELSQTPGHTEELANGAADSFTSAPKQTPDSGKP----- 2595
Q R E+ + + P T + AA + + P S P
Sbjct: 1771 KALQKRVEDEQKGRSKLPIRVKGKEDVPKKTTHRPHPAASPSLKSERHAPGSPSPKTERH 1830
Query: 2596 --LKISRRVLRAPKVEPVGDVVSTRDPVKSQSKSNTSLPPLPFKRGGGKDGSVTGTKRLR 2653
L S + R P V P PV +K+ P + TK R
Sbjct: 1831 STLSSSAKTERHPPVSP-SSKTEKHSPVSPSAKTERHSPASSSSKTEKHSPVSPSTKTER 1889
Query: 2654 CMPAPEEIVEELP-------ASKKQRVAPRARGKSSEPVVIMKRSLRTSAKRIEPAEELN 2706
P E P K+ V+P R + PV S + KR+ +
Sbjct: 1890 HSPVSSTKTERHPPVSPSGKTDKRPPVSPSGRTEKHPPV-----SPGRTEKRLPVSPSGR 1944
Query: 2707 SNDMKTNKEEHKLQDSVPENKGISLRSRRQNKTEAEQQITEVFVLAERIEINRNEKKPMK 2766
++ + K + +P + KTE + ++ ERIE + ++ MK
Sbjct: 1945 TDKHQPVSTAGKTEKHLPVSP--------SGKTEKQPPVSPT-SKTERIEETMSVRELMK 1995
Query: 2767 TSPEMDIQNPDDGARKPIPRDKVTENKRCLRSARQNESSQPKVAEESGGQKSAKVLMQNQ 2826
Q+ D ++ +K L + + QP Q+ KV ++ +
Sbjct: 1996 A-----FQSGQDPSK----------HKTGLFEHKSAKQKQP--------QEKGKVRVEKE 2032
Query: 2827 KG----KGEAGNSDSMCLRSRKTKSQPAASTLESKSVQRVTRSVKRCAENPKKAEDNVCV 2882
KG + EA +++ + ++ + P T ESK RV+ S+ E+ ++ V
Sbjct: 2033 KGPILTQREAQKTENQTI--KRGQRLPVTGTAESKRGVRVS-SIGVKKEDAAGGKEKVLS 2089
Query: 2883 KKI--------RTRSHRDSE 2894
KI SHR+SE
Sbjct: 2090 HKIPEPVQSVPEEESHRESE 2109
>gi|153945728 microtubule-associated protein 1B [Homo sapiens]
Length = 2468
Score = 65.1 bits (157), Expect = 1e-09
Identities = 219/1039 (21%), Positives = 371/1039 (35%), Gaps = 193/1039 (18%)
Query: 1354 IELFQTPSHTKESMTNE------KTTKVSYRASQPDLVDTPTSSKPQPKRSLRKADTEEE 1407
++ + P T++ +T + K TK+ RA + + ++KP P +S+RK EE
Sbjct: 508 LDFLKQPLATQKDLTGQVPTPVVKQTKLKQRADSRESLKP--AAKPLPSKSVRKESKEE- 564
Query: 1408 FLAFRKQTPSAGKAMHTPKPA---------VGEEKDINTFLGTPVQKLDQPGNLPGSNRR 1458
TP K H KP V ++K I T V + + P S +
Sbjct: 565 -------TPEVTKVNHVEKPPKVESKEKVMVKKDKPIKTETKPSVTEKEVPSKEEPSPVK 617
Query: 1459 LQTRKEKA-----QALEELTGFRELFQTPCTDNPTTDEKTTKKILCKSPQSDPADTPTNT 1513
+ +++A +A +E T +E P D EK K++ K + TP
Sbjct: 618 AEVAEKQATDVKPKAAKEKTVKKETKVKP-EDKKEEKEKPKKEVAKKEDK-----TPIKK 671
Query: 1514 KQRPKRSLKKADVEEEFLAFRKLTPSAGKAMHTPKAAV------GEEKDINTFVGTPVEK 1567
+++PK+ K +V++E K P TP V E+K++ P ++
Sbjct: 672 EEKPKKEEVKKEVKKEIKKEEKKEPKKEVKKETPPKEVKKEVKKEEKKEVKKEEKEPKKE 731
Query: 1568 LDLLGNLPGSKRRPQTPKEKAKALEDLAGFKELFQTPGHTEESMTDDKITEVSCKSPQPD 1627
+ LP ++ TP +AK L + P EES+ D + K
Sbjct: 732 IK---KLPKDAKKSSTPLSEAKKPAALKP-----KVP-KKEESVKKDSVAAGKPK----- 777
Query: 1628 PVKTPTSSKQRLKISLGKVGVKEEVLPVGKLTQTSGKTTQTHRETAGDGK--SIKAFKES 1685
K ++K+ + K G E + T G TT AG K +
Sbjct: 778 -------EKGKIKV-IKKEGKAAEAVAAAVGT---GATTAAVMAAAGIAAIGPAKELEAE 826
Query: 1686 AKQMLDPANYGTGMERWPRTPKEEAQSLEDLAGFKELFQTPDHTEES--------TTDDK 1737
M P + E EE +D+ EL + + +E+ + +
Sbjct: 827 RSLMSSPEDLTKDFE---ELKAEEVDVTKDIKPQLELIEDEEKLKETEPVEAYVIQKERE 883
Query: 1738 TTKIACKSPPPESMDTPTSTRRRPKTPLGKRDIVEELSALKQLTQTTHTDKVPGDEDKGI 1797
TK +S P E + T +TP EEL +++ D + ED+G
Sbjct: 884 VTKGPAES-PDEGITTTEGEGECEQTP-------EELEPVEK----QGVDDIEKFEDEGA 931
Query: 1798 NVFRETAKQKLDPAASVTGSKRQPR--------TPKGKAQPLEDLAGLKELFQTPICTDK 1849
F E+++ + T +P K P ED K I
Sbjct: 932 G-FEESSETGDYEEKAETEEAEEPEEDGEEHVCVSASKHSPTEDEESAKAEADAYI---- 986
Query: 1850 PTTHEKTTKIACRSPQPDPVGTPTIFKPQSKRSLRKADVEEESLALRKRTPSVGK----- 1904
EK +A + + I K ++++S +AD E+++ R+ K
Sbjct: 987 ---REKRESVASGDDRAEEDMDEAIEKGEAEQSEEEADEEDKAEDAREEEYEPEKMEAED 1043
Query: 1905 ----AMDTPKPAGGDEKDMKAFMGTPVQKL--DLPGNLPGSKRWPQTPKEKAQALEDLAG 1958
+D AGG E + F+ TP ++L PG P S +T +++ E A
Sbjct: 1044 YVMAVVDKAAEAGGAE-EQYGFLTTPTKQLGAQSPGREPASSIHDETLPGGSES-EATAS 1101
Query: 1959 FKELFQTPGTDKPTTDEKTTKIACKSPQPDPVD---TPASTKQRPKRNLRKADVEEEFLA 2015
+E + + T T S +P P+D TP N +EF+
Sbjct: 1102 DEENREDQPEEFTATSGYTQSTIEISSEPTPMDEMSTPRDVMSDETNNEETESPSQEFVN 1161
Query: 2016 LRKRTPSAGKAMDTPKPAVSDEKNINTFVETPVQKLDLLG----NLPGSKRQPQTPKEK- 2070
+ K S + + KPA D +N F E K D N S P + E+
Sbjct: 1162 ITKYESSL-YSQEYSKPA--DVTPLNGFSEG--SKTDATDGKDYNASASTISPPSSMEED 1216
Query: 2071 ---AEALEDLVGFKELFQTPGHTEESMTDDKITEVS-CKSPQPESFKTSRSSKQRLKIPL 2126
AL D + T ++S++ +VS KSP S K L
Sbjct: 1217 KFSRSALRDAYCSEVKASTTLDIKDSISAVSSEKVSPSKSPSLSPSPPSPLEKTPLGERS 1276
Query: 2127 VKVDMKEEPLAVS---KLTRTSGETTQTHTEPTGDSKSIKAFKESPKQILDPAASVTGSR 2183
V + + VS ++ S E TQ E S K +++ P+ SVTGS
Sbjct: 1277 VNFSLTPNEIKVSAEAEVAPVSPEVTQEVVEEHCASPEDKTL-----EVVSPSQSVTGS- 1330
Query: 2184 RQLRTRKEKARALEDLVDFKELFSAPGHTE--ESMTIDKNTKIPCK--SPPP------EL 2233
GHT +S T +K++ +P + PP E
Sbjct: 1331 -------------------------AGHTPYYQSPTDEKSSHLPTEVIEKPPAVPVSFEF 1365
Query: 2234 TDTATSTKRCPKTRPRKEVKEELSAVERL-----------TQTSGQSTHTHKEPASGDEG 2282
+D +R + + V + S +E++ ++++ +S + + ASG
Sbjct: 1366 SDAKDENERASVSPMDEPVPDSESPIEKVLSPLRSPPLIGSESAYESFLSADDKASGRGA 1425
Query: 2283 IKVLKQRAKKKPNPVEEEP 2301
++++ K+ +P + P
Sbjct: 1426 ESPFEEKSGKQGSPDQVSP 1444
Score = 60.5 bits (145), Expect = 2e-08
Identities = 168/874 (19%), Positives = 306/874 (35%), Gaps = 131/874 (14%)
Query: 1831 LEDLAGLKEL--FQTPICTDKPTTHEKTTKIACRSPQPDPVGTPTIFKPQSKRSLRKADV 1888
LE L LK L + P+ T K T + T + ++ + KP +K L V
Sbjct: 499 LEGLEKLKHLDFLKQPLATQKDLTGQVPTPVVKQTKLKQRADSRESLKPAAK-PLPSKSV 557
Query: 1889 EEESLALRKRTPSVGKAMDTPKPAGGDEKD---------MKAFMGTPVQKLDLPGNLPGS 1939
+ES ++ TP V K KP + K+ +K V + ++P S
Sbjct: 558 RKES---KEETPEVTKVNHVEKPPKVESKEKVMVKKDKPIKTETKPSVTEKEVPSKEEPS 614
Query: 1940 KRWPQTPKEKAQALEDLAGFKELFQTPGTDKPTTDEKTTKIACKSPQPDPVDTPASTKQR 1999
+ +++A ++ A ++ + KP ++ + K TP +++
Sbjct: 615 PVKAEVAEKQATDVKPKAAKEKTVKKETKVKPEDKKEEKEKPKKEVAKKEDKTPIKKEEK 674
Query: 2000 PKRNLRKADVEEEFLALRKRTPSAGKAMDTPKPAVSDE------KNINTFVETPVQKLDL 2053
PK+ K +V++E K+ P +TP V E K + + P +++
Sbjct: 675 PKKEEVKKEVKKEIKKEEKKEPKKEVKKETPPKEVKKEVKKEEKKEVKKEEKEPKKEIKK 734
Query: 2054 LGNLPGSKRQPQTPKEKAEALEDLVGFKELFQTPGHTEESMTDDKITEVSCKSPQPESFK 2113
L P + +K AL+ V K EES+ D +
Sbjct: 735 LPKDAKKSSTPLSEAKKPAALKPKVPKK---------EESVKKDSV-------------- 771
Query: 2114 TSRSSKQRLKIPLVKVDMKEEPLAVSKLTRTSGETTQTHTEPTGDSKSIKAFKESPKQIL 2173
+ K++ KI ++K + K + + +G TT G
Sbjct: 772 AAGKPKEKGKIKVIKKEGKAAEAVAAAV--GTGATTAAVMAAAG---------------- 813
Query: 2174 DPAASVTGSRRQLRTRKEKARALEDLV-DFKELFSAPGHTEESMTIDKNTKIPCKSPPPE 2232
+ G ++L + + EDL DF+EL E + + K+ K P E
Sbjct: 814 ---IAAIGPAKELEAERSLMSSPEDLTKDFEEL------KAEEVDVTKDIK-----PQLE 859
Query: 2233 LTDTATSTKRCPKTRPRKEVKEELSAVERLTQTSGQSTHTHKEPA-SGDEGIKVLKQRAK 2291
L + K +T P V+ + ER K PA S DEGI + +
Sbjct: 860 LIEDEEKLK---ETEP---VEAYVIQKER---------EVTKGPAESPDEGITTTEGEGE 904
Query: 2292 KKPNPVEEEPSRRRPRAPKEKAQPLEDLAGFTELSETSGHTQESLTAGKATKIPCESPPL 2351
+ P E EP ++ EK + ++ AGF E SET + + KA E P
Sbjct: 905 CEQTPEELEPVEKQGVDDIEKFE--DEGAGFEESSETGDYEE------KAETEEAEEPEE 956
Query: 2352 EVVD-TTASTKRHLRTRVQKVQVKEEPSAVKFTQTSGETTDADKEPAGEDKGIKALKESA 2410
+ + S +H T ++ E + ++ + S + D D+ D+ I+ +
Sbjct: 957 DGEEHVCVSASKHSPTEDEESAKAEADAYIREKRESVASGD-DRAEEDMDEAIEKGEAEQ 1015
Query: 2411 KQTPAPAASVTGSRRRPRAPRESAQAIEDLAGFKDPA--AGHTEESMTDDKTTKIPCKSS 2468
+ A R E +A + + D A AG EE + ++
Sbjct: 1016 SEEEADEEDKAEDAREEEYEPEKMEAEDYVMAVVDKAAEAGGAEE--------QYGFLTT 1067
Query: 2469 PELEDTATSSKRRPRTRAQKVEVKEELLAVGKLTQTSGETTHTDKEPVGEGKGTKAFKQ- 2527
P + A S R P + + +E L G ++ + ++ E T + Q
Sbjct: 1068 PTKQLGAQSPGREPAS-----SIHDETLPGGSESEATASDEENREDQPEEFTATSGYTQS 1122
Query: 2528 ---------PAKRKLDAEDVIGSRRQPRAPKEKAQPLEDLASFQELSQTPGHTEELANGA 2578
P DV+ + +Q ++ ++ + +++
Sbjct: 1123 TIEISSEPTPMDEMSTPRDVMSDETNNEETESPSQEFVNITKYESSLYSQEYSKPADVTP 1182
Query: 2579 ADSFTSAPKQTPDSGKPLKISRRVLRAPK--VEPVGDVVSTRDPVKSQSKSNTSLPPLPF 2636
+ F+ K GK S + P E + RD S+ K++T+L +
Sbjct: 1183 LNGFSEGSKTDATDGKDYNASASTISPPSSMEEDKFSRSALRDAYCSEVKASTTL-DIKD 1241
Query: 2637 KRGGGKDGSVTGTKRLRCMPAPEEIVEELPASKK 2670
V+ +K P+P +E+ P ++
Sbjct: 1242 SISAVSSEKVSPSKSPSLSPSPPSPLEKTPLGER 1275
Score = 60.5 bits (145), Expect = 2e-08
Identities = 354/1813 (19%), Positives = 622/1813 (34%), Gaps = 313/1813 (17%)
Query: 824 EKDIKAFMGTPVQKLDLAGTLPGSKRQLQTPKEKAQALEDLAGFKELFQTPGHTEELVAA 883
+KD+ + TPV K S+ L K A+ L + KE + ++
Sbjct: 518 QKDLTGQVPTPVVKQTKLKQRADSRESL---KPAAKPLPSKSVRKESKEETPEVTKVNHV 574
Query: 884 GKTTKIPCDSPQSDPVDTPTSTKQRPKRSIRKADVEGELLACRNLMPSAGKAMHTPKPSV 943
K K+ D P T+ +P S+ + +V + A K KP
Sbjct: 575 EKPPKVESKEKVMVKKDKPIKTETKP--SVTEKEVPSKEEPSPVKAEVAEKQATDVKPKA 632
Query: 944 GEEKDIIIFVGTPVQKLDLTENLTGSKRRPQTPKEEAQALEDLTGFKELFQTPGHTEEAV 1003
+EK + K + K + PK+E ED T K+ + P E
Sbjct: 633 AKEKTV---------KKETKVKPEDKKEEKEKPKKEVAKKEDKTPIKKE-EKPKKEEVKK 682
Query: 1004 AAGKTTKMPCESSPPESA--DTPTSTRRQPKTPLEKRDVQKELSALKKLTQTSGETTHTD 1061
K K + P + +TP ++ EK++V+KE KK + +
Sbjct: 683 EVKKEIKKEEKKEPKKEVKKETPPKEVKKEVKKEEKKEVKKEEKEPKKEIKKLPKDAKKS 742
Query: 1062 KVPGGEDKSINAFRETAKQKLDPAASVTGSKRHPKTKEKAQPLEDLAGLKELFQTPVCTD 1121
P E K A + +K + + + PK K K + ++ E V T
Sbjct: 743 STPLSEAKKPAALKPKVPKKEESVKKDSVAAGKPKEKGKIKVIKKEGKAAEAVAAAVGTG 802
Query: 1122 KPT--------------------------THEKTTKIACRSQPDPVDTPTSSKPQSKRSL 1155
T + E TK + + VD KPQ L
Sbjct: 803 ATTAAVMAAAGIAAIGPAKELEAERSLMSSPEDLTKDFEELKAEEVDVTKDIKPQ----L 858
Query: 1156 RKVDVEEEFFALRKRTPSAGKAMHTPKPAVSGEKNIYAFMGTPVQKLDLTENLTGSKRRL 1215
++ EE+ L++ P + + G +P + + TE G
Sbjct: 859 ELIEDEEK---LKETEPVEAYVIQKEREVTKGPAE------SPDEGITTTE---GEGECE 906
Query: 1216 QTPKE----KAQALEDLAGFKELFQTRGHTEESMTNDKTAKVACKSSQPDPDKNPASSKR 1271
QTP+E + Q ++D+ F++ + G E S T D K + ++ +P+++
Sbjct: 907 QTPEELEPVEKQGVDDIEKFED--EGAGFEESSETGDYEEKAETEEAE-EPEED------ 957
Query: 1272 RLKTSLGKVGVKEELLAVGKLTQTSGETTHTHTEPTGDGKSMKAFMESPKQILDSAASLT 1331
EE + V + + PT D +S KA E+ I + S+
Sbjct: 958 -----------GEEHVCV----------SASKHSPTEDEESAKA--EADAYIREKRESVA 994
Query: 1332 GSKRQLRTPKGKSEVPEDLAGFIELFQTPSHTKESMTNEKTTKVSYRASQPDLVDTPTSS 1391
G ED+ IE + +E+ +K +P+
Sbjct: 995 ---------SGDDRAEEDMDEAIEKGEAEQSEEEADEEDKAEDAREEEYEPE-------- 1037
Query: 1392 KPQPKRSLRKADTEEEFLAFRKQTPSAGKAMHTPKPAVGEEKDINTFLGTPVQKL--DQP 1449
K + E+ +A + AG G E+ FL TP ++L P
Sbjct: 1038 ---------KMEAEDYVMAVVDKAAEAG----------GAEEQYG-FLTTPTKQLGAQSP 1077
Query: 1450 GNLPGSNRRLQT----RKEKAQALEELTGFRELFQTPCTDNPTTDEKTTKKILCKSPQSD 1505
G P S+ +T + +A A +E + + T T ++T +I + D
Sbjct: 1078 GREPASSIHDETLPGGSESEATASDEENREDQPEEFTATSGYT---QSTIEISSEPTPMD 1134
Query: 1506 PADTPTNTKQRPKRSLKKADVEEEFLAFRKLTPSAGKAMHTPKAAVGEEKDINTF-VGTP 1564
TP + + + +EF+ K S ++ A V +N F G+
Sbjct: 1135 EMSTPRDVMSDETNNEETESPSQEFVNITKYESSLYSQEYSKPADV---TPLNGFSEGSK 1191
Query: 1565 VEKLDLLG-NLPGSKRRPQTPKEKAK----ALEDLAGFKELFQTPGHTEESMTDDKITEV 1619
+ D N S P + E+ K AL D + T ++S++ +V
Sbjct: 1192 TDATDGKDYNASASTISPPSSMEEDKFSRSALRDAYCSEVKASTTLDIKDSISAVSSEKV 1251
Query: 1620 S-CKSPQ-----PDPVKTPTSSKQRLKISLG----KVGVKEEVLPVGKLTQTSGKTTQTH 1669
S KSP P P++ ++ + SL KV + EV PV + + + + H
Sbjct: 1252 SPSKSPSLSPSPPSPLEKTPLGERSVNFSLTPNEIKVSAEAEVAPVS--PEVTQEVVEEH 1309
Query: 1670 RETAGDGKSIKAFKESAKQMLDPANYGTGMERWPRTPKEEAQSLEDLAGFKELFQTPDHT 1729
+ D K+++ S G + ++P +E S ++ P
Sbjct: 1310 CASPED-KTLEVVSPS-----QSVTGSAGHTPYYQSPTDEKSSHLPTEVIEKPPAVPVSF 1363
Query: 1730 EESTTDDKTTKIACKSPPPESMDTPTSTRRRPKTPLGKRDIVEELSALKQLTQTTHTDKV 1789
E S D+ + A SP E + S + +PL ++ SA + DK
Sbjct: 1364 EFSDAKDENER-ASVSPMDEPVPDSESPIEKVLSPLRSPPLIGSESAYESFLSA--DDKA 1420
Query: 1790 PG-------DEDKGINVFRETAKQKLDPAASVTGSKRQPRTPKGKAQPLEDLAGLKELFQ 1842
G +E G ++ + ++ P + +T + +GK+ D A +KE F
Sbjct: 1421 SGRGAESPFEEKSG----KQGSPDQVSPVSEMTSTSLYQDKQEGKS---TDFAPIKEDFG 1473
Query: 1843 TPICTD-------KPTTHEKTTKIACRSPQPDPVGTPTIFKPQSKRSLRKADVEEESLAL 1895
TD +P K+ SP V FK +K S+ + V ++S
Sbjct: 1474 QEKKTDDVEAMSSQPALALDERKLGDVSPTQIDVSQFGSFKEDTKMSISEGTVSDKS--- 1530
Query: 1896 RKRTP-SVGKAMDTPKPAGGDEKDMKAFMGTPVQKLDLPGNLPGSKRWPQTPKEKAQALE 1954
TP G A DT G A + T ++ S + +
Sbjct: 1531 --ATPVDEGVAEDTYSHMEGVASVSTASVATSSFPEPTTDDVSPSLHAEVGSPHSTEVDD 1588
Query: 1955 DLAGFKELFQTPGTDKPTTDEKTTKIACKSPQ--PDPVDTPASTKQRPKRNLRKADVEEE 2012
L+ + QTP T + T+ +K C P P +P + K R +++
Sbjct: 1589 SLS--VSVVQTPTTFQ-ETEMSPSKEECPRPMSISPPDFSPKTAKSRTPVQDHRSEQSSM 1645
Query: 2013 FLALRKRTPSAGKAMDTPKPAVSDEKNINTFVETPVQKLDLLGNLPGSKRQPQTPKEKAE 2072
+ + +P AMD + + D + V + + S Q + K
Sbjct: 1646 SIEFGQESPEQSLAMDFSRQS-PDHPTVGAGVLHITENGPTEVDYSPSDMQDSSLSHKIP 1704
Query: 2073 ALEDLVGFKELFQTPGHTEESMTDDKITEVSCKSPQPESFKTSRSSKQRLKIPLVKVDMK 2132
+E+ P +T+++ + I+ VS P + +S + ++ PL + +
Sbjct: 1705 PMEE----------PSYTQDNDLSELIS-VSQVEASPST--SSAHTPSQIASPLQEDTLS 1751
Query: 2133 E--EPLAVSKLTRTSGETTQTHTEPTGDSKSIKAFKESPKQILDPAASVTGSRRQLRTRK 2190
+ P +S + E Q S++ K SPK + P S T
Sbjct: 1752 DVAPPRDMSLYASLTSEKVQ----------SLEGEKLSPKSDISPLTPRESSPLYSPTFS 1801
Query: 2191 EKARALEDLVDFKELFSAPGHTEESMTIDKNTKIPCKSPPPELTDTATSTKRCPKTRPRK 2250
+ A+++ +A H+ S ID + P L DT +
Sbjct: 1802 DSTSAVKEK-------TATCHSSSSPPIDAASAEPYGFRASVLFDTMQHHLALNRDLSTP 1854
Query: 2251 EVKEELSAVERLTQTSGQSTHTHKEPASGDEGIKVLKQRAKKKPNPVEEEPSRRRPRAPK 2310
++++ +T G ++ +++P EE + R+P
Sbjct: 1855 GLEKDSGG-----KTPGDFSYAYQKP----------------------EETT----RSPD 1883
Query: 2311 EKAQPLEDLAGFTELSETSGHTQESLTAGKATKIPCESP-PLEVVDTTASTKRHLRTRVQ 2369
E+ E T S+ G+ E + + TK P +S E + T T
Sbjct: 1884 EEDYDYESYEKTTRTSDVGGYYYEKIE--RTTKSPSDSGYSYETIGKTTKT--------- 1932
Query: 2370 KVQVKEEPSAVKFTQTSGETTDADKEPAGEDKGIKALKESAKQTPAPAASVTGSRRRPRA 2429
P ++ E T E G I S K T P S + R
Sbjct: 1933 -------PEDGDYSYEIIEKTTRTPEEGGYSYDI-----SEKTTSPPEVSGYSYEKTER- 1979
Query: 2430 PRESAQAIEDLAGFKDPA--AGHT--EESMTDDKTTKIPCKSSPELE----DTATSSKRR 2481
S + ++D++ D + GHT + S + + T KI S PE E +T+T + R
Sbjct: 1980 ---SRRLLDDISNGYDDSEDGGHTLGDPSYSYETTEKI--TSFPESEGYSYETSTKTTRT 2034
Query: 2482 PRTRAQKVEVKEELLAVGKLTQTSGETTHTDKEPVGEGKGTKAFKQPAKRKLDAEDVIGS 2541
P T E E K+T+T +T++ + + T K P++ + D + + S
Sbjct: 2035 PDTSTYCYETAE------KITRTPQASTYSYE--TSDLCYTAEKKSPSEARQDVDLCLVS 2086
Query: 2542 RRQPRAPKEKAQP 2554
+ + PK + P
Sbjct: 2087 SCEYKHPKTELSP 2099
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 64.3 bits (155), Expect = 2e-09
Identities = 361/1822 (19%), Positives = 639/1822 (35%), Gaps = 319/1822 (17%)
Query: 1117 PVCTDKPTTHEKTTKIACRSQPDPVDT---PTSSKPQSKRSLRKVDVEEEFFALRKRTPS 1173
P KP EK K + R + + V P SK + + V+EE ++
Sbjct: 9178 PKVIKKPVI-EKIEKTSRRMEEEKVQVTKVPEVSKKIVPQKPSRTPVQEEVIEVKV---- 9232
Query: 1174 AGKAMHTPKPAVSGEKNIYAF-------MGTP-VQKLDLTE---NLTGSKRRLQTPK--- 1219
A+HT K +S EK +A + P VQK +TE ++ SKR PK
Sbjct: 9233 --PAVHTKKMVISEEKMFFASHTEEEVSVTVPEVQKEIVTEEKIHVAISKRVEPPPKVPE 9290
Query: 1220 -EKAQALEDLAGFKELFQTRGHTEESMTNDKTAKVACKSSQPDPDKNPASSKRRLKTSLG 1278
+ A E++A + + K K P P K PA+ + +
Sbjct: 9291 LPEKPAPEEVAPVPIPKKVEPPAPKVPEVPKKPVPEEKKPVPVPKKEPAAPPK--VPEVP 9348
Query: 1279 KVGVKEELLAVGKLTQTSGETTHTHTEPTGDGKSMKAFM-----ESPKQILDSAASLTGS 1333
K V EE + V + G K + ESP +
Sbjct: 9349 KKPVPEEKIPVPVAKKKEAPPAKVPEVQKGVVTEEKITIVTQREESPPPAVPEIPKKKVP 9408
Query: 1334 KRQLRTPKGKSEVPEDLAGFIELFQTPSHTKESMTNEKTTKVSYRASQPDLVDTPTSSKP 1393
+ + P+ + EVP + P+ K+ + EK V P + K
Sbjct: 9409 EERKPVPRKEEEVPPPP-------KVPALPKKPVPEEKVA-----------VPVPVAKKA 9450
Query: 1394 QPKR---SLRKADTEEEFLAFRKQTPSAGKAMHTPKPAVGEEKDINTFLGTPVQKLDQPG 1450
P R S + E+ F+A K + + + + + V E++ + ++
Sbjct: 9451 PPPRAEVSKKTVVEEKRFVAEEKLSFAVPQRVEVTRHEVSAEEEWSYS--------EEEE 9502
Query: 1451 NLPGSNRRLQTRKEKAQALEELTGFRELFQTPCTDNPTTDEKTTKKILCKSPQSDPADTP 1510
+ S R + R+E+ +A E+T + E+ + P + +EK I+ K +++PA+
Sbjct: 9503 GVSISVYREEEREEEEEA--EVTEY-EVMEEP--EEYVVEEKL--HIISKRVEAEPAEV- 9554
Query: 1511 TNTKQRPKRSLKK----ADVEEEFLAFRKLTPSAGKAMHTPKAAVGEEKDINTFVGTPVE 1566
T+++ K+ + K A +EE P K PK V E+K V PV
Sbjct: 9555 --TERQEKKIVLKPKIPAKIEE---------PPPAKVPEAPKKIVPEKK-----VPAPVP 9598
Query: 1567 KLDLLGNLPGSKRRPQTPKEKAKALEDLAGFKELFQTPGHTEESMT---DDKITEVSCKS 1623
K + + P P+ P + K + +E TE M ++K+ K
Sbjct: 9599 KKEKVPP-PKVPEEPKKPVPEKKVPPKVIKMEEPLPAKV-TERHMQITQEEKVLVAVTKK 9656
Query: 1624 PQPDPVKTPTSSKQRL-KISLGKVGVKEEVLPVGKLTQTSGKTTQTHRETAGDGKSIKAF 1682
P + P K+ + + + K+ K E P K+T+ + K K
Sbjct: 9657 EAPPKARVPEEPKRAVPEEKVLKLKPKREEEPPAKVTEFRKRVV----------KEEKVS 9706
Query: 1683 KESAKQMLDPANYGTGMERWPR--TPKEEAQSLEDLAGFKEL--FQTPDHTEESTTDDKT 1738
E+ K+ P T ME R T +EEA S++ ++E + + E T++
Sbjct: 9707 IEAPKREPQPIKEVTIMEEKERAYTLEEEAVSVQREEEYEEYEEYDYKEFEEYEPTEEYD 9766
Query: 1739 TKIACKSPPPESMDTPTSTRRRPKTPLGKRDIVEELSALKQLTQTTHTDKVPGDEDKGIN 1798
+ E + P+ P+ + + EE K K P +
Sbjct: 9767 QYEEYEEREYERYEEHEEYITEPEKPIPVKPVPEEPVPTKP--------KAPPAK----- 9813
Query: 1799 VFRETAKQKLDPAASVTGSKRQPRTPKGKAQPLEDLAGLKELFQTPI-CTDKPTTHEKTT 1857
V ++ ++ P K +P PK +P K++F+ I + E+ T
Sbjct: 9814 VLKKAVPEEKVPVP--IPKKLKPPPPKVPEEP-------KKVFEEKIRISITKREKEQVT 9864
Query: 1858 KIACRSPQPDPVGTPTIFKPQSKRSLRKADVEEESLALRKRTPSVGKAMDTPKPAGGDEK 1917
+ A + P KP+ + K V + +A R P V K ++ + A +E
Sbjct: 9865 EPAAKVPM----------KPKRVVAEEKVPVPRKEVAPPVRVPEVPKELEPEEVAFEEE- 9913
Query: 1918 DMKAFMGTPVQKLDLPGNLPGSKRWPQTPKEKAQALEDLAGFKELFQTPGTDKPTTDEKT 1977
+ T V++ + + +E E+ +E+ P K
Sbjct: 9914 -----VVTHVEEYLV-----------EEEEEYIHEEEEFITEEEVVPVIPVKVPEVPRKP 9957
Query: 1978 TKIACKSPQPDPVDT---PASTKQRPKRNLRKADVEEEFLALRKRTPSAGKAMDTPKPAV 2034
K P P P PA + PK+ K V L +K P K + PK V
Sbjct: 9958 VPEE-KKPVPVPKKKEAPPAKVPEVPKKPEEKVPV----LIPKKEKPPPAKVPEVPKKPV 10012
Query: 2035 SDEKNINTFVETPVQKLDLLGNLPGSKRQPQTPKEKAEALEDLVGFKELFQTPGHTEESM 2094
+EK V PV K P +K P+ PK+ + V + + P +
Sbjct: 10013 PEEK-----VPVPVPKKV---EAPPAK-VPEVPKKPVPEKKVPVPAPKKVEAPPAKVPEV 10063
Query: 2095 TDDKITEVSCKSPQPESFKTSRSSKQRLKIPLVKVDMKEEPLAVSKLTRTSGETTQTHTE 2154
I E +P P+ +++ P KV K EP+ V + E E
Sbjct: 10064 PKKLIPEEKKPTPVPK----------KVEAPPPKVPKKREPVPVP-VALPQEEEVLFEEE 10112
Query: 2155 PTGDSKSIKAFKE---SPKQILDPAASVTGSRRQLRTRKEKARALEDLVDFKELFSAPGH 2211
+ + + +E +++L V ++ +E+ E+ V +E F
Sbjct: 10113 IVPEEEVLPEEEEVLPEEEEVLPEEEEVLPEEEEIPPEEEEVPPEEEYVPEEEEFVP--- 10169
Query: 2212 TEESMTIDKNTKIPCKSPPPELTDTATSTK---------------RCPKTRPRKEV---- 2252
EE + + K+P +P PE+ T K PK K +
Sbjct: 10170 -EEEVLPEVKPKVPVPAPVPEIKKKVTEKKVVIPKKEEAPPAKVPEVPKKVEEKRIILPK 10228
Query: 2253 KEELSAVERLTQTSGQSTHTHK---EPASGDEGIKV--------LKQRAKKKPNPV---- 2297
+EE+ VE + + + EP S +E +V +K+ + P PV
Sbjct: 10229 EEEVLPVEVTEEPEEEPISEEEIPEEPPSIEEVEEVAPPRVPEVIKKAVPEAPTPVPKKV 10288
Query: 2298 EEEPSRRRPRAPKEKAQ-PLEDL-AGFTELSETSGHTQESLTAGKATKIPCES--PPLE- 2352
E P++ + P+EK P++ A ++ E E K +P + PP +
Sbjct: 10289 EAPPAKVSKKIPEEKVPVPVQKKEAPPAKVPEVPKKVPE-----KKVLVPKKEAVPPAKG 10343
Query: 2353 --VVDTTAST--------KRHLRTRVQKVQVKEEPSAVKFTQTSG-----------ETTD 2391
V++ S K L V + +V+E P +F + E
Sbjct: 10344 RTVLEEKVSVAFRQEVVVKERLELEVVEAEVEEIPEEEEFHEVEEYFEEGEFHEVEEFIK 10403
Query: 2392 ADKEPAGEDKGIKALKESAKQTPAPAASVTGSRRRPRAPRESAQAIEDLAGFKDPAAGHT 2451
++ E+ ++ + + A V +P+AP + + E + K P
Sbjct: 10404 LEQHRVEEEHRVEKVHRVIEVFEAEEVEVF---EKPKAPPKGPEISEKIIPPKKPPTKVV 10460
Query: 2452 EESMTDDKTTKIPCKSSPELEDTATSSKRRPRTRAQKVEVKEELLAVGKLTQTSGETTHT 2511
K ++P K E + R P T+ +V +E++ K+
Sbjct: 10461 PRKEPPAKVPEVPKKIVVEEKVRVPEEPRVPPTKVPEVLPPKEVVPEKKV---------- 10510
Query: 2512 DKEPVGEGKGTKAFKQPAKRKLDAEDVIGSRRQPRAPKEKAQPLEDLASFQELSQTPGHT 2571
PV K +A P K ++V+ ++ P P +K P E+ +
Sbjct: 10511 ---PVPPAKKPEA--PPPKVPEAPKEVVPEKKVPVPPPKK--PEVPPTKVPEVPKAAVPE 10563
Query: 2572 EELANGAADSFTSAPKQTPDSGKPLKISRRVLRAPKVEP-VGDVVSTRDPVKSQSKSNTS 2630
+++ S P + P++ K + ++V AP +P V V P + +
Sbjct: 10564 KKVPEAIPPKPESPPPEVPEAPKEVVPEKKVPAAPPKKPEVTPVKVPEAPKEVVPEKKVP 10623
Query: 2631 LPP------LPFKRGGGKDGSVTGTKRLRCMP------------APEEI-VEELPASKKQ 2671
+PP P K +V K +P PEE+ +EE PA +
Sbjct: 10624 VPPPKKPEVPPTKVPEVPKVAVPEKKVPEAIPPKPESPPPEVFEEPEEVALEEPPAEVVE 10683
Query: 2672 RVAPRARGKSSEPVVIMKRSLRTSAKRIEPAEELNSNDMKTNKEEHKLQDSVPENKGISL 2731
P A P + + ++ PA ++ K ++ VPE K +
Sbjct: 10684 EPEPAA------PPQVTVPPKKPVPEKKAPAVVAKKPELPPVKVPEVPKEVVPEKKVPLV 10737
Query: 2732 RSRRQNKTEAE-QQITEVFVLAERIEINRNEKKPMKTSPEMDIQNPDDGARKPIPRDKVT 2790
++ A+ ++ + V +++ + + + P PE +P+ V
Sbjct: 10738 VPKKPEAPPAKVPEVPKEVVPEKKVAVPKKPEVPPAKVPE-------------VPKKPVL 10784
Query: 2791 ENKRCLRSARQNESSQPKVAEE 2812
E K + + ES P+V EE
Sbjct: 10785 EEKPAVPVPERAESPPPEVYEE 10806
Score = 59.3 bits (142), Expect = 5e-08
Identities = 389/1964 (19%), Positives = 689/1964 (35%), Gaps = 322/1964 (16%)
Query: 935 AMHTPKPSVGEEKDII-------IFVGTP-VQKLDLTE---NLTGSKRRPQTPKEEAQAL 983
A+HT K + EEK + V P VQK +TE ++ SKR PK L
Sbjct: 9234 AVHTKKMVISEEKMFFASHTEEEVSVTVPEVQKEIVTEEKIHVAISKRVEPPPK--VPEL 9291
Query: 984 EDLTGFKELFQTPGHTEEAVAAGKTTKMPCESSPPESADTPTSTRRQ---PKTP-LEKRD 1039
+ +E+ P + A K ++P + P E P + PK P + K+
Sbjct: 9292 PEKPAPEEVAPVPIPKKVEPPAPKVPEVPKKPVPEEKKPVPVPKKEPAAPPKVPEVPKKP 9351
Query: 1040 VQKELSALKKLTQTSGETTHTDKVPGGEDKSINAFRETAKQKLDPAASVTGSKRHPKTKE 1099
V +E + + +V G T +++ P A K+ +
Sbjct: 9352 VPEEKIPVPVAKKKEAPPAKVPEVQKGVVTEEKITIVTQREESPPPAVPEIPKKKVPEER 9411
Query: 1100 KAQPLEDLAGLKELFQTPVCTDKPTTHEKTTKIACRSQPDPVDTPTSSKPQSKRSLRKVD 1159
K P ++ + + P KP EK + P PV + P+++ S + V
Sbjct: 9412 KPVPRKE-EEVPPPPKVPALPKKPVPEEKV------AVPVPV-AKKAPPPRAEVSKKTVV 9463
Query: 1160 VEEEFFALRKRTPSAGKAMHTPKPAVSGEKNIYAFMGTPVQKLDLTENLTGSKRRLQTPK 1219
E+ F A K + + + + + VS E+ ++ ++ ++ + R + +
Sbjct: 9464 EEKRFVAEEKLSFAVPQRVEVTRHEVSAEEE----WSYSEEEEGVSISVYREEEREEEEE 9519
Query: 1220 EKAQALEDLAGFKE--------LFQTRGHTEESMTNDKTAK-------VACKSSQPDPDK 1264
+ E + +E + R E + ++ K + K +P P K
Sbjct: 9520 AEVTEYEVMEEPEEYVVEEKLHIISKRVEAEPAEVTERQEKKIVLKPKIPAKIEEPPPAK 9579
Query: 1265 NPASSKRRLKTSLGKVGV-KEELLAVGKLTQTSGETTHTHTEPTGDGKSMKAFMESPKQI 1323
P + K+ + V K+E + K+ + + P K +K P ++
Sbjct: 9580 VPEAPKKIVPEKKVPAPVPKKEKVPPPKVPEEPKKPVPEKKVPP---KVIKMEEPLPAKV 9636
Query: 1324 LDSAASLTGSKRQL-----RTPKGKSEVPEDLAGFI--ELFQTPSHTKESMTNEKTTKVS 1376
+ +T ++ L + K+ VPE+ + E +E K T+
Sbjct: 9637 TERHMQITQEEKVLVAVTKKEAPPKARVPEEPKRAVPEEKVLKLKPKREEEPPAKVTEFR 9696
Query: 1377 YRASQPDLVDTPTSSK-PQPKRSLRKADTEEEFLAFRKQTPSAGKAMHTPKPAVGEEKDI 1435
R + + V + PQP + + + +E ++ S + + + K+
Sbjct: 9697 KRVVKEEKVSIEAPKREPQPIKEVTIMEEKERAYTLEEEAVSVQREEEYEEYEEYDYKEF 9756
Query: 1436 NTFLGTPVQKLDQPGNLPGSNRRLQTRKEKAQALEELTGFRELFQTPCTDNPTTDEKTTK 1495
+ P ++ DQ R + +E + + E + P PT +
Sbjct: 9757 EEY--EPTEEYDQYEEY--EEREYERYEEHEEYITEPEKPIPVKPVPEEPVPTKPKAPPA 9812
Query: 1496 KILCKSPQSDPADTPTNTKQRPK-----RSLKKADVEEEFLAFRK-----LTPSAGKAMH 1545
K+L K+ + P K +P KK E+ ++ K +T A K
Sbjct: 9813 KVLKKAVPEEKVPVPIPKKLKPPPPKVPEEPKKVFEEKIRISITKREKEQVTEPAAKVPM 9872
Query: 1546 TPKAAVGEEKDINTFVGTPVEKLDLLGNLPGSKRRPQTPKEKAKALEDLAGFKELFQTPG 1605
PK V EEK PV + ++ + R P+ PKE E++A F+E T
Sbjct: 9873 KPKRVVAEEK-------VPVPRKEVAPPV----RVPEVPKELEP--EEVA-FEEEVVT-- 9916
Query: 1606 HTEESMTDDK----------ITE------VSCKSPQPDPVKTPTSSKQRLKISLGKVGVK 1649
H EE + +++ ITE + K P+ P K K+ + + K
Sbjct: 9917 HVEEYLVEEEEEYIHEEEEFITEEEVVPVIPVKVPEV-PRKPVPEEKKPVPVPKKKEAPP 9975
Query: 1650 EEVLPVGKLTQTSGKTTQTHRETAGDGKSIKAFKESAKQMLDPANYGTGME----RWPRT 1705
+V V K + +E K + K+ + P +E + P
Sbjct: 9976 AKVPEVPKKPEEKVPVLIPKKEKPPPAKVPEVPKKPVPEEKVPVPVPKKVEAPPAKVPEV 10035
Query: 1706 PKEEAQSLEDLAGFKELFQTPDHTEESTTDDKTTKIACKSPPPESMDTPTSTRRR---PK 1762
PK+ ++ P + K ++ K P E TP + PK
Sbjct: 10036 PKKPVP--------EKKVPVPAPKKVEAPPAKVPEVPKKLIPEEKKPTPVPKKVEAPPPK 10087
Query: 1763 TPLGKRDIVEELSALKQLTQTTHTDKVPGDEDKGINVFRETAKQKLDPAASVTGSKRQPR 1822
P KR+ V AL Q + +++ +E+ V E ++++ P + +
Sbjct: 10088 VPK-KREPVPVPVALPQEEEVLFEEEIVPEEE----VLPE--EEEVLPEEEEVLPEEEEV 10140
Query: 1823 TPKGKAQPLEDLAGLKELFQTPICTDKPTTHEKTTKIACRSPQPDPVGTPTIFKPQSKRS 1882
P+ + P E+ E P + E ++ + P P PV P I K K +
Sbjct: 10141 LPEEEEIPPEEEEVPPEEEYVPEEEEFVPEEEVLPEVKPKVPVPAPV--PEIKK---KVT 10195
Query: 1883 LRKADVEEESLALRKRTPSVGKAMDTPKPAGGDEKDMKAFMGTPVQKLDLPGNLPGSKRW 1942
+K + ++ A + P V K ++ + E+++ PV+ + P P S+
Sbjct: 10196 EKKVVIPKKEEAPPAKVPEVPKKVEEKRIILPKEEEV-----LPVEVTEEPEEEPISEEE 10250
Query: 1943 PQTPKEKAQALEDLAGFKELFQTPGTDKPTTDEKTTKIACKSPQPDPVDTPASTKQRPKR 2002
+ +E++A P E K ++P P P
Sbjct: 10251 IPEEPPSIEEVEEVA------------PPRVPEVIKKAVPEAPTPVP------------- 10285
Query: 2003 NLRKADVEEEFLALRKRTPSAGKAMDTPKPAVSDEKNINTFVETPVQKLDLLGNLPGSKR 2062
K ++ P PA +K V PVQK + P +K
Sbjct: 10286 ----------------------KKVEAP-PAKVSKKIPEEKVPVPVQKKEA----PPAK- 10317
Query: 2063 QPQTPKEKAEALEDLVGFKELFQTPGHTEESMTDDKITEVSCKSPQPESFKTSRSSKQRL 2122
P+ PK+ E + LV KE P ++ ++K++ +F+ K+RL
Sbjct: 10318 VPEVPKKVPEK-KVLVPKKEA--VPPAKGRTVLEEKVSV---------AFRQEVVVKERL 10365
Query: 2123 KIPLVKVDMKEEPLAVSKLTRTSGETTQTHTEPTGDSKSIKAFKESPKQILDPAASVTGS 2182
++ +V+ +++E P E + H + F+E ++ +
Sbjct: 10366 ELEVVEAEVEEIP-----------EEEEFHEVE-------EYFEEGEFHEVEEFIKLEQH 10407
Query: 2183 RRQLRTRKEKARALEDLVDFKEL--FSAPGHTEESMTIDKNTKIPCKSPPPELTDTATST 2240
R + R EK + ++ + +E+ F P + I + IP K PP ++
Sbjct: 10408 RVEEEHRVEKVHRVIEVFEAEEVEVFEKPKAPPKGPEISEKI-IPPKKPPTKVVPRKEPP 10466
Query: 2241 KRCPKTRPRKEVKEELSAVERLTQTSGQSTHTHKEPASGDEGIKVLKQRAKKKPNPVEEE 2300
+ P+ P+K V EE V + P KV AKK P +
Sbjct: 10467 AKVPEV-PKKIVVEEKVRVPEEPRVPPTKVPEVLPPKEVVPEKKVPVPPAKKPEAPPPKV 10525
Query: 2301 PSRRRPRAPKEKAQ---PLEDLAGFTELSETSGHTQESLTAGKATKIPCESPPLEVVDTT 2357
P + P++K P + T++ E +A ESPP EV +
Sbjct: 10526 PEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKAAVPEKKVPEAIPPKPESPPPEVPEAP 10585
Query: 2358 ASTKRHLRTRVQKVQVKEEPSAVKFTQTSGETTDADKEPAGEDKGIKALKESAKQTPAPA 2417
+ + K E + VK + E K P K + + P A
Sbjct: 10586 KEVVPEKKVPAAPPK-KPEVTPVKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKVA 10644
Query: 2418 ASVTGSRRRPRA--------PRESAQAIEDLAGFKDPAAGHTEESMTDDKTTKIPCKSSP 2469
++ P A P E + E++A ++P A EE P ++P
Sbjct: 10645 VP---EKKVPEAIPPKPESPPPEVFEEPEEVA-LEEPPAEVVEE----------PEPAAP 10690
Query: 2470 ELEDTATSSKRRPRTRAQKVEVKEELLAVGKLTQTSGETTHTDKEPVGEGKGTKAFKQPA 2529
+ T K P +A V K+ L K+ + E K P+ K +A PA
Sbjct: 10691 P-QVTVPPKKPVPEKKAPAVVAKKPELPPVKVPEVPKEVVPEKKVPLVVPKKPEA--PPA 10747
Query: 2530 KRKLDAEDVIGSRRQPRAPKEKAQPLEDLASFQELSQTPGHTEELANGAADSFTSAPKQT 2589
K ++V+ ++ K + P A E+ + P E+ A + S P +
Sbjct: 10748 KVPEVPKEVVPEKKVAVPKKPEVPP----AKVPEVPKKPVLEEKPAVPVPERAESPPPEV 10803
Query: 2590 PDSGKPLKISRRVLRAPKVE-PVGDVVSTRDPVKSQSKSNTSLPPLPFKRGGGKDGSVTG 2648
+ +P +I+ AP+ E PV PV + + P +P +
Sbjct: 10804 YE--EPEEIAPEEEIAPEEEKPV--------PVAEEEEPEVPPPAVPEE----------- 10842
Query: 2649 TKRLRCMPAPEEIVEE--LPASKKQRVAPRARGKSSEPV-VIMKRSLRTSAKRIEPAEEL 2705
P++I+ E +P KK P K EP VI K L+ PA
Sbjct: 10843 ---------PKKIIPEKKVPVIKKPEAPPP---KEPEPEKVIEKPKLKPRPPPPPPAPP- 10889
Query: 2706 NSNDMKTNKEEHKLQDSVPENKGISLRSRRQNKTEAEQQITEVFVLAERIEINRNEKKPM 2765
KE+ K K L++ + K + Q+ E L +++ EKK
Sbjct: 10890 --------KEDVK-------EKIFQLKAIPKKKVPEKPQVPEKVELTP-LKVPGGEKKVR 10933
Query: 2766 KTSPEMDIQNPDDGARKPIPRDKVTENKRCLRSARQNESSQPKV 2809
K PE RKP P+++V K LR ++ E +PKV
Sbjct: 10934 KLLPE----------RKPEPKEEVV-LKSVLR--KRPEEEEPKV 10964
Score = 55.1 bits (131), Expect = 1e-06
Identities = 271/1400 (19%), Positives = 490/1400 (35%), Gaps = 222/1400 (15%)
Query: 1506 PADTPTNTKQRPKRSLKKADVEEEFLAFRKLTPSAGKAMHTPKAA--VGEEKDINTFVGT 1563
PA P P + +KK +E+ R++ + P+ + + +K T
Sbjct: 9166 PAKVPEKKAPPPPKVIKKPVIEKIEKTSRRMEEEKVQVTKVPEVSKKIVPQKPSRT---- 9221
Query: 1564 PVEKLDLLGNLPGSKRRPQTPKEKAKALEDLAGFKELFQTPGHTEESMTDDKITEVSCKS 1623
PV++ + +P + E+ + P +E +T++KI K
Sbjct: 9222 PVQEEVIEVKVPAVHTKKMVISEEKMFFASHTEEEVSVTVPEVQKEIVTEEKIHVAISKR 9281
Query: 1624 PQPDPVKTPTSSKQRLKISLGKVGVKEEVLPVG---KLTQTSGKTTQTHRETAGDGKSIK 1680
+P P K P L + EEV PV K+ + K + ++ + K K
Sbjct: 9282 VEPPP-KVP---------ELPEKPAPEEVAPVPIPKKVEPPAPKVPEVPKKPVPEEK--K 9329
Query: 1681 AFKESAKQMLDPANYGTGMERWPRTPKEEAQSLEDLAGFKEL--FQTPDHTEESTTDDKT 1738
K+ P + P+ P E + +A KE + P+ + T++K
Sbjct: 9330 PVPVPKKEPAAPPK----VPEVPKKPVPEEKIPVPVAKKKEAPPAKVPEVQKGVVTEEKI 9385
Query: 1739 TKIACK--SPPPESMDTPTSTRRRPKTPLGKRDIVEELSALKQLTQTTHTDKVPGDEDKG 1796
T + + SPPP + P + K P ++ + + + + K P E+K
Sbjct: 9386 TIVTQREESPPPAVPEIP-----KKKVPEERKPVPRKEEEVPPPPKVPALPKKPVPEEK- 9439
Query: 1797 INVFRETAKQKLDPAASVTGSKRQPRTPKGKAQPLEDLAGLKELFQTPICTDKPTTHEKT 1856
+ V AK+ P A V+ K + +A K F P + T HE +
Sbjct: 9440 VAVPVPVAKKAPPPRAEVS--------KKTVVEEKRFVAEEKLSFAVPQRVEV-TRHEVS 9490
Query: 1857 TKIACRSPQPDPVGTPTIFKPQSKRSLRKADVEE-------ESLALRKRTPSVGKAMDTP 1909
+ + + + ++++ + + +A+V E E + ++ + K ++
Sbjct: 9491 AEEEWSYSEEEEGVSISVYREEEREEEEEAEVTEYEVMEEPEEYVVEEKLHIISKRVEA- 9549
Query: 1910 KPAGGDEKDMKAFMGTPVQKLDLPGNLPGSKRWPQTPKEKAQALEDLAGFKELFQTPGTD 1969
+PA E+ K K+ L +P P K P
Sbjct: 9550 EPAEVTERQEK--------KIVLKPKIPAKIEEPPPAK-----------------VPEAP 9584
Query: 1970 KPTTDEKTTKIACKSPQPDPVDTPASTKQRPKRNLRKADVEEEFLALRKRTPSAGKAMDT 2029
K EK K+ P+ + V P + PK+ + + K+ P M+
Sbjct: 9585 KKIVPEK--KVPAPVPKKEKVPPP-KVPEEPKKPVPE-----------KKVPPKVIKMEE 9630
Query: 2030 PKPAVSDEKNINTFVETPVQKLDLLGNLPGSKRQPQTPK-----EKAEALEDLVGFKELF 2084
P PA E+++ E V P R P+ PK EK L+ +
Sbjct: 9631 PLPAKVTERHMQITQEEKVLVAVTKKEAPPKARVPEEPKRAVPEEKVLKLKPKREEEPPA 9690
Query: 2085 QTPGHTEESMTDDKIT-EVSCKSPQPESFKTSRSSKQR---LKIPLVKVDMKEEPLAVSK 2140
+ + + ++K++ E + PQP T K+R L+ V V +EE +
Sbjct: 9691 KVTEFRKRVVKEEKVSIEAPKREPQPIKEVTIMEEKERAYTLEEEAVSVQREEEYEEYEE 9750
Query: 2141 LTRTSGE----TTQTHTEPTGDSKSIKAFKESPKQILD-----PAASVTGSRRQLRTRKE 2191
E T + + + + ++E + I + P V + +
Sbjct: 9751 YDYKEFEEYEPTEEYDQYEEYEEREYERYEEHEEYITEPEKPIPVKPVPEEPVPTKPKAP 9810
Query: 2192 KARALEDLVDF--------KELFSAPGHT--EESMTIDKNTKIP-CKSPPPELTDTATST 2240
A+ L+ V K+L P E ++ +I K ++T+ A
Sbjct: 9811 PAKVLKKAVPEEKVPVPIPKKLKPPPPKVPEEPKKVFEEKIRISITKREKEQVTEPAAKV 9870
Query: 2241 KRCPK--------TRPRKEV---------------------KEELSAVER-LTQTSGQST 2270
PK PRKEV +E ++ VE L + +
Sbjct: 9871 PMKPKRVVAEEKVPVPRKEVAPPVRVPEVPKELEPEEVAFEEEVVTHVEEYLVEEEEEYI 9930
Query: 2271 HTHKEPASGDEGIKVLKQRA----------KKKPNPV---EEEPSRRRPRAPKEKAQPLE 2317
H +E + +E + V+ + +KKP PV +E P + P PK+ + +
Sbjct: 9931 HEEEEFITEEEVVPVIPVKVPEVPRKPVPEEKKPVPVPKKKEAPPAKVPEVPKKPEEKVP 9990
Query: 2318 DLAGFTELSETSGHTQESLTAGKATKIP------CESPPLEVVDTTASTKRHLRTRVQKV 2371
L E + + K+P E+PP +V + + V
Sbjct: 9991 VLIPKKEKPPPAKVPEVPKKPVPEEKVPVPVPKKVEAPPAKVPEVPKKPVPEKKVPVPAP 10050
Query: 2372 QVKEEPSAVKFTQTSGETTDADKEPAGEDKGIKA--LKESAKQTPAPAASVTGSRRRPRA 2429
+ E P A K + + +K+P K ++A K K+ P P
Sbjct: 10051 KKVEAPPA-KVPEVPKKLIPEEKKPTPVPKKVEAPPPKVPKKREPVPVPVALPQEEEVLF 10109
Query: 2430 PRESAQAIEDLAGFKDPAAGHTEESMTDDKTTKIPCKSSPELEDTATSSKRRPRTRAQKV 2489
E E L ++ E +++ + PE E+ + P ++
Sbjct: 10110 EEEIVPEEEVLPEEEEVLPEEEEVLPEEEEVLPEEEEIPPEEEEVPPEEEYVP--EEEEF 10167
Query: 2490 EVKEELLAVGKLTQTSGETTHTDKEPVGEGKGTKAFKQ---PAK-----RKLDAEDVIGS 2541
+EE+L K K+ V E K K+ PAK +K++ + +I
Sbjct: 10168 VPEEEVLPEVKPKVPVPAPVPEIKKKVTEKKVVIPKKEEAPPAKVPEVPKKVEEKRIILP 10227
Query: 2542 RRQPRAPKE-KAQPLEDLASFQELSQTPGHTEELANGAADSFTSAPKQTPDSGKPLKISR 2600
+ + P E +P E+ S +E+ + P EE+ AP + P+ I +
Sbjct: 10228 KEEEVLPVEVTEEPEEEPISEEEIPEEPPSIEEVEE-------VAPPRVPE-----VIKK 10275
Query: 2601 RVLRAPKVEPVGDVVSTRDPVKSQSKSNTSLPPLPFKRGGGKDGSVTGTKRLRCMPAPEE 2660
V AP PV V P K K P+P ++ V P++
Sbjct: 10276 AVPEAP--TPVPKKVEA-PPAKVSKKIPEEKVPVPVQKKEAPPAKVP--------EVPKK 10324
Query: 2661 IVEELPASKKQRVAPRARGKS--SEPVVIMKRSLRTSAKRIE-PAEELNSNDMKTNKEEH 2717
+ E+ K+ P A+G++ E V + R +R+E E ++ +E H
Sbjct: 10325 VPEKKVLVPKKEAVPPAKGRTVLEEKVSVAFRQEVVVKERLELEVVEAEVEEIPEEEEFH 10384
Query: 2718 KLQDSVPE------NKGISLRSRR---QNKTEAEQQITEVFVLAERIEINRNEKKPMKTS 2768
++++ E + I L R +++ E ++ EVF AE +E+ K P K
Sbjct: 10385 EVEEYFEEGEFHEVEEFIKLEQHRVEEEHRVEKVHRVIEVFE-AEEVEVFEKPKAPPK-G 10442
Query: 2769 PEMD--IQNPDDGARKPIPR 2786
PE+ I P K +PR
Sbjct: 10443 PEISEKIIPPKKPPTKVVPR 10462
Score = 42.7 bits (99), Expect = 0.005
Identities = 139/717 (19%), Positives = 229/717 (31%), Gaps = 131/717 (18%)
Query: 1608 EESMTDDKITEVSCKSPQPDPVKTPTSSKQRLKISLGKVGVKEEVLPVGKLTQTSGKTTQ 1667
+E + + K+ K P+ P K P + K EV+P K+ K +
Sbjct: 10502 KEVVPEKKVPVPPAKKPEAPPPKVPEAPK--------------EVVPEKKVPVPPPKKPE 10547
Query: 1668 THRETAGDGKSIKAFKESAKQMLDPANYGTGMERWPRTPKEEAQSLE-DLAGFKELFQTP 1726
+ ++ + + P E P PKE + A K+ TP
Sbjct: 10548 VPPTKVPEVPKAAVPEKKVPEAIPPKPESPPPEV-PEAPKEVVPEKKVPAAPPKKPEVTP 10606
Query: 1727 DHTEESTTDDKTTKIACKSPPPESMDTPTSTRRRPKTPLGKRDIVEELSALKQLTQTTHT 1786
E+ + K PP + PT PK + ++ + E +
Sbjct: 10607 VKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKVAVPEKKVPEAIP----------- 10655
Query: 1787 DKVPGDEDKGINVFRETAKQKLDPAASVTGSKRQPRTPKGKAQPLEDLAGLKELFQTPIC 1846
P E VF E + L+ + + +P P Q +
Sbjct: 10656 ---PKPESPPPEVFEEPEEVALEEPPAEVVEEPEPAAPP----------------QVTVP 10696
Query: 1847 TDKPTTHEKTTKIACRSPQPDPVGTPTIFKPQSKRSLRKADVEEESLALRKRTPSVGKAM 1906
KP +K + + P+ PV P + K V ++ A + P V K +
Sbjct: 10697 PKKPVPEKKAPAVVAKKPELPPVKVPEVPKEVVPEKKVPLVVPKKPEAPPAKVPEVPKEV 10756
Query: 1907 DTPKPAGGDEKDMKAFMGTP-VQK---LDLPGNLPGSKRWPQTPKEKAQALEDLAGFKEL 1962
K +K P V K L+ +P +R P E + E++A +E+
Sbjct: 10757 VPEKKVAVPKKPEVPPAKVPEVPKKPVLEEKPAVPVPERAESPPPEVYEEPEEIAPEEEI 10816
Query: 1963 FQTPGTDKPTTDEKTTKIACKSPQPDPVDTPASTKQRPKRNLRKADVEEEFLALRKRTPS 2022
P +KP + + +P P + + PK+ + + K+ P
Sbjct: 10817 --APEEEKPVP---------VAEEEEPEVPPPAVPEEPKKIIPE-----------KKVPV 10854
Query: 2023 AGKAMDTPKPAVSDEKNINTFVETPVQKLDLLGNLPGSKRQPQTPKEKAEALEDLVGFKE 2082
K P EK +E P K + P P E +++ + +
Sbjct: 10855 IKKPEAPPPKEPEPEK----VIEKPKLK---------PRPPPPPPAPPKEDVKEKIFQLK 10901
Query: 2083 LFQTPGHTEESMTDDKITEVSCKSPQPESFKTSRSSKQRLKIPLVKVDMKEEPLAVSKLT 2142
E+ +K+ K P E K R +P K + KEE + S L
Sbjct: 10902 AIPKKKVPEKPQVPEKVELTPLKVPGGEK-------KVRKLLPERKPEPKEEVVLKSVLR 10954
Query: 2143 RTSGETTQTHTEPTGDSKSIKAFKES-------PKQILDPAASVTGSRRQLRTRKEKARA 2195
+ E EP + K ++ K+ PK + + R + K
Sbjct: 10955 KRPEEE-----EPKVEPKKLEKVKKPAVPEPPPPKPVEEVEVPTVTKRERKIPEPTKVPE 11009
Query: 2196 LEDLVDFKELFSAPGHTEESMTIDKNTKIPCKSPPPELTDTATSTKRCPKTRPRKEVKEE 2255
++ + P E TI K PP E T + P T P K E
Sbjct: 11010 IKPAIPLPAPEPKPKPEAEVKTI--------KPPPVEPEPTPIAA---PVTVPVVGKKAE 11058
Query: 2256 LSAVERLTQTSGQSTHTHKEPASGDEGIKVLKQRAKKKPNPVEEEPSRRRPRAPKEK 2312
A KE A+ +G +K KK P+P+E E + RP + EK
Sbjct: 11059 AKAP--------------KEEAAKPKG--PIKGVPKKTPSPIEAERRKLRPGSGGEK 11099
Score = 40.8 bits (94), Expect = 0.020
Identities = 142/681 (20%), Positives = 234/681 (34%), Gaps = 100/681 (14%)
Query: 1896 RKRTPSVGKAMDTPKPAGGDEK----DMKAFMGTPVQKLDLPGNLPGSKRWPQTPKEKAQ 1951
RK P+ K + PK +EK + T V ++ P + K+ P P +K +
Sbjct: 10462 RKEPPA--KVPEVPKKIVVEEKVRVPEEPRVPPTKVPEVLPPKEVVPEKKVPVPPAKKPE 10519
Query: 1952 ALEDLAGFKELFQTPGTDKPTTDEKTTKIACKSPQPDPVDTPASTKQRPKRNLRKADVEE 2011
A + P K EK + P P P + PK + + V E
Sbjct: 10520 APPP--------KVPEAPKEVVPEKKVPVP---PPKKPEVPPTKVPEVPKAAVPEKKVPE 10568
Query: 2012 EFLALRKRTPSAGKAMDTPKPAVSDEKNINTFVE----TPVQKLDLLGNLPGSKRQPQTP 2067
+ P + + PK V ++K + TPV+ + + K+ P P
Sbjct: 10569 AIPPKPESPPP--EVPEAPKEVVPEKKVPAAPPKKPEVTPVKVPEAPKEVVPEKKVPVPP 10626
Query: 2068 KEKAEALEDLVGFKELFQTPGHTEESMTDDKITEV---SCKSPQPESFKTSRSSKQRLKI 2124
+K E V P + ++ + K+ E +SP PE F+ + L+
Sbjct: 10627 PKKPEVPPTKV--------PEVPKVAVPEKKVPEAIPPKPESPPPEVFE--EPEEVALEE 10676
Query: 2125 PLVKVDMKEEPLAVSKLTRTSGETTQTHTEPTGDSKSIKAFKESPKQILDPAASVTGSRR 2184
P +V + EP A ++T +P + K+ + P+ P V +
Sbjct: 10677 PPAEVVEEPEPAAPPQVTVPP-------KKPVPEKKAPAVVAKKPEL---PPVKVPEVPK 10726
Query: 2185 QLRTRKEKARALEDLVDFKELFSAPGHTEE---SMTIDKNTKIPCKS--PPPELTDTATS 2239
++ K+ LV K+ + P E + +K +P K PP ++ +
Sbjct: 10727 EVVPEKKVP-----LVVPKKPEAPPAKVPEVPKEVVPEKKVAVPKKPEVPPAKVPEV--- 10778
Query: 2240 TKRCPKTRPRKEVKEELSAVERLTQTSGQSTHTHKEPASGDEGIKVLKQRAKKKPNPVEE 2299
P+K V EE AV + ++EP ++ + K P EE
Sbjct: 10779 --------PKKPVLEEKPAVPVPERAESPPPEVYEEPEEIAPEEEIAPEEEKPVPVAEEE 10830
Query: 2300 EPSRRRPRAPKE--KAQPLEDLAGFTELSETSGHTQESLTAGKATKIPCESPPLEVVDTT 2357
EP P P+E K P + + + E + K+ PP
Sbjct: 10831 EPEVPPPAVPEEPKKIIPEKKVPVIKKPEAPPPKEPEPEKVIEKPKLKPRPPPPPPAPPK 10890
Query: 2358 ASTKRHL--RTRVQKVQVKEEPSAVKFTQTSGETTDADKEPAGEDKGIKALKESAKQTPA 2415
K + + K +V E+P + + + K P GE K K L E + P
Sbjct: 10891 EDVKEKIFQLKAIPKKKVPEKPQVPEKVELT-----PLKVPGGEKKVRKLLPE---RKPE 10942
Query: 2416 PAASVTGSRRRPRAPRESAQAIE--DLAGFKDPAAGHTEESMTDDKTTKIPCKSSPELED 2473
P V + P E +E L K PA P K E+E
Sbjct: 10943 PKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPP-----------PPKPVEEVEV 10991
Query: 2474 TATSSKRRPRTRAQKV-EVKEELLAVGKLTQTSGET-THTDKEPVGEGKGTKAFKQPAKR 2531
+ + R KV E+K + + E T K P E + T P
Sbjct: 10992 PTVTKRERKIPEPTKVPEIKPAIPLPAPEPKPKPEAEVKTIKPPPVEPEPT-----PIAA 11046
Query: 2532 KLDAEDVIGSRRQPRAPKEKA 2552
+ V+G + + +APKE+A
Sbjct: 11047 PVTV-PVVGKKAEAKAPKEEA 11066
Score = 38.1 bits (87), Expect = 0.13
Identities = 68/304 (22%), Positives = 117/304 (38%), Gaps = 32/304 (10%)
Query: 2268 QSTHTHKEPASGDEGIKVLKQRAKKKPN----PVEEEPSRRRPRAPKEKAQPLEDLAGFT 2323
+ +H K PA KV +++A P PV E+ + R +EK Q T
Sbjct: 9158 EESHERKVPA------KVPEKKAPPPPKVIKKPVIEKIEKTSRRMEEEKVQ-------VT 9204
Query: 2324 ELSETSGHTQESLTAGKATKIPCESPPLEVVDTTASTKRHLRTRVQKVQVK--EEPSAVK 2381
++ E S + + K ++ P + +EV TK+ + + + EE +V
Sbjct: 9205 KVPEVS----KKIVPQKPSRTPVQEEVIEVKVPAVHTKKMVISEEKMFFASHTEEEVSVT 9260
Query: 2382 FTQTSGETTDADKEPAGEDKGI----KALKESAKQTPAPAASVTGSRR-RPRAPRESAQA 2436
+ E +K K + K + K P A V ++ P AP+
Sbjct: 9261 VPEVQKEIVTEEKIHVAISKRVEPPPKVPELPEKPAPEEVAPVPIPKKVEPPAPKVPEVP 9320
Query: 2437 IEDLAGFKDPAAGHTEESMTDDKTTKIPCKSSPELEDTATSSKRRPRTRAQKVEVKEELL 2496
+ + K P +E K ++P K PE + +K++ A+ EV++ ++
Sbjct: 9321 KKPVPEEKKPVPVPKKEPAAPPKVPEVPKKPVPEEKIPVPVAKKKEAPPAKVPEVQKGVV 9380
Query: 2497 AVGKLT-QTSGETTHTDKEPVGEGKGTKAFKQPAKRKLDAEDVIGSRRQPRAPKEKAQPL 2555
K+T T E + P K ++P RK E+V + P PK K P
Sbjct: 9381 TEEKITIVTQREESPPPAVPEIPKKKVPEERKPVPRK--EEEVPPPPKVPALPK-KPVPE 9437
Query: 2556 EDLA 2559
E +A
Sbjct: 9438 EKVA 9441
Score = 37.0 bits (84), Expect = 0.28
Identities = 100/525 (19%), Positives = 193/525 (36%), Gaps = 93/525 (17%)
Query: 1602 QTPGHTEESMTDDKITEVSCKSPQPDPVKTPTSSKQRLKISLGKVGVKEEVLPVGKLTQT 1661
+ P +E + + K+ K P+ PVK P + K EV+P K+
Sbjct: 10580 EVPEAPKEVVPEKKVPAAPPKKPEVTPVKVPEAPK--------------EVVPEKKVPVP 10625
Query: 1662 SGKTTQTHRETAGDGKSIKAFKESAKQMLDPANYGTGMERWPRTPKEEA-QSLEDLAGFK 1720
K + + + ++ + + P P +P E + E++A +
Sbjct: 10626 PPKKPEVPPTKVPEVPKVAVPEKKVPEAIPPK---------PESPPPEVFEEPEEVALEE 10676
Query: 1721 ELFQTPDHTEESTTDDKTTKIACKSPPPESMDTPTSTRRRPKTPLGK-----RDIVEELS 1775
+ + E + T + K P PE P ++P+ P K +++V E
Sbjct: 10677 PPAEVVEEPEPAAPPQVT--VPPKKPVPEK-KAPAVVAKKPELPPVKVPEVPKEVVPEKK 10733
Query: 1776 ALKQLTQTTHTD--KVPGDEDKGINVFRETAKQKLD-PAASVTGSKRQPRTPKGKAQPLE 1832
+ + KVP + + + +K + P A V ++P + A P+
Sbjct: 10734 VPLVVPKKPEAPPAKVPEVPKEVVPEKKVAVPKKPEVPPAKVPEVPKKPVLEEKPAVPVP 10793
Query: 1833 DLAGL--KELFQTP--ICTDKPTTHEKTTKIACRSPQPDPVGTPTIFKPQSKRSL---RK 1885
+ A E+++ P I ++ E+ + + V P + P+ + + +K
Sbjct: 10794 ERAESPPPEVYEEPEEIAPEEEIAPEEEKPVPVAEEEEPEVPPPAV--PEEPKKIIPEKK 10851
Query: 1886 ADVEEESLALRKRTPSVGKAMDTPK-----------PAGGDEKD----MKAFMGTPV--- 1927
V ++ A + P K ++ PK P D K+ +KA V
Sbjct: 10852 VPVIKKPEAPPPKEPEPEKVIEKPKLKPRPPPPPPAPPKEDVKEKIFQLKAIPKKKVPEK 10911
Query: 1928 ----QKLDL-PGNLPGSKRWPQ--TPKEKAQALEDLAGFKELFQTPGTDKPTTD----EK 1976
+K++L P +PG ++ + P+ K + E++ L + P ++P + EK
Sbjct: 10912 PQVPEKVELTPLKVPGGEKKVRKLLPERKPEPKEEVVLKSVLRKRPEEEEPKVEPKKLEK 10971
Query: 1977 TTKIACKSPQP----DPVDTPASTKQRPKRNLRKADVEEEFLALRKRTPSAGKAMDTPKP 2032
K A P P + V+ P TK+ RK + ++ P + P+P
Sbjct: 10972 VKKPAVPEPPPPKPVEEVEVPTVTKRE-----RKIPEPTKVPEIKPAIP-----LPAPEP 11021
Query: 2033 AVSDEKNINTFVETPVQ------KLDLLGNLPGSKRQPQTPKEKA 2071
E + T PV+ + + G K + + PKE+A
Sbjct: 11022 KPKPEAEVKTIKPPPVEPEPTPIAAPVTVPVVGKKAEAKAPKEEA 11066
Score = 35.4 bits (80), Expect = 0.83
Identities = 43/162 (26%), Positives = 62/162 (38%), Gaps = 37/162 (22%)
Query: 113 RKIREQEPARR-------VSRSSFSSDPDESEGI--PLKRRRVSFGGHLRPELFDENLPP 163
+K+R+ P R+ V +S P+E E P K +V P PP
Sbjct: 10930 KKVRKLLPERKPEPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEP-------PP 10982
Query: 164 NTPLKRGEAPT--KRKSLVMH---TPPVLKKIIKEQPQPSGKQESGSEIHVEVKAQSLVI 218
P++ E PT KR+ + P + I P+P K E+ EVK I
Sbjct: 10983 PKPVEEVEVPTVTKRERKIPEPTKVPEIKPAIPLPAPEPKPKPEA------EVKT----I 11032
Query: 219 SPPAPSPRKTPVASDQRRRSCKTAPASSSKSQTEVPKRGGRK 260
PP P TP+A+ T P K++ + PK K
Sbjct: 11033 KPPPVEPEPTPIAAP------VTVPVVGKKAEAKAPKEEAAK 11068
>gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapiens]
Length = 1341
Score = 62.8 bits (151), Expect = 5e-09
Identities = 159/787 (20%), Positives = 291/787 (36%), Gaps = 114/787 (14%)
Query: 2140 KLTRTSGETTQTHTEPTGDSKSIKAFKESPKQILDPAASVTGSRRQLRTRKEKARALEDL 2199
+L+R S + + +E GDS E P++ G RR R R+ +A L +
Sbjct: 197 ELSRHSPRKSSSISEEKGDSDD-----EKPRK---------GERRSSRVRQARAAKLSE- 241
Query: 2200 VDFKELFSAPGHTEESM-TIDKNTKIPCKSPPPELTDTATSTKRCPKTRPRKEVKEELSA 2258
S P EE T +N ++ R KT +E +EE
Sbjct: 242 ------GSQPAEEEEDQETPSRNLRV--------------RADRNLKTEEEEEEEEEEEE 281
Query: 2259 VERLTQTSGQSTHTHKEPASGDEGIKVLKQRAKKKPNPVEEEPSRRRPRAPKEKAQPLED 2318
+ + + + + P +K K+ ++ P EE RP+ ++ + LE
Sbjct: 282 DDEEEEGDDEGQKSREAPI-----LKEFKEEGEEIPRVKPEEMMDERPKTRSQEQEVLER 336
Query: 2319 LAGFTELSETSGHTQESLTAGKATKIPCESPPLEVVDTTASTKRHLRTRVQKVQVKEEPS 2378
FT E + + L + K + PLE + + + L+ + + PS
Sbjct: 337 GGRFTRSQEEA--RKSHLARQQQEKEMKTTSPLEEEEREIKSSQGLKEK------SKSPS 388
Query: 2379 AVKFTQTSGETTDADKEPAGEDKGIKALKE---SAKQTPAPAASVTGSRRRPRAPRESAQ 2435
+ T+ D++ A + AL E S ++TP P + S P S +
Sbjct: 389 PPRLTE--------DRKKA----SLVALPEQTASEEETPPPLLTKEASSPPPHPQLHSEE 436
Query: 2436 AIEDLAGFKDPAAGHTEESMTDDKTTKIPCKSSP-----ELEDTATSSKRRPRTRAQKVE 2490
IE + G P TD T ++ L ++ S + + A+KV
Sbjct: 437 EIEPMEGPAPPVLIQLSPPNTDADTRELLVSQHTVQLVGGLSPLSSPSDTKAESPAEKVP 496
Query: 2491 VKEELLAVGKLTQTSGETTHTDKEPVGEGKGTKAFKQPAKRKLD----AEDVIGS-RRQP 2545
+E +L + + + + + D EP + QP K++ A+ + +QP
Sbjct: 497 -EESVLPLVQKSTLADYSAQKDLEPESDRSA-----QPLPLKIEELALAKGITEECLKQP 550
Query: 2546 R-APKEKAQPLEDLASFQELSQTPGHTEELANGAADSFTSAPKQTPDSG-----KPLKIS 2599
KE + L L Q+ + ++ ++ S + + ++PDS PL+
Sbjct: 551 SLEQKEGRRASHTLLPSHRLKQSADSSSSRSSSSSSSSSRSRSRSPDSSGSRSHSPLRSK 610
Query: 2600 RR-VLRA-----PKVEPVGDVVST---RDPVKSQSKSNTSLPPLPFKRGGGKDGSVTGTK 2650
+R V +A P+ P ST R +S+S+S +S G +D S + T+
Sbjct: 611 QRDVAQARTHANPRGRPKMGSRSTSESRSRSRSRSRSASSNSRKSLSPGVSRDSSTSYTE 670
Query: 2651 RLRCMPAPEEIVEELPASKKQRVAPRARGKSSEPVVIMKRSLRTSAKRIEPAEELNSNDM 2710
P+ + V P + Q P+ R +S V +R + + + L
Sbjct: 671 TKD--PSSGQEVATPPVPQLQVCEPKERTSTSSSSVQARRLSQPESAEKHVTQRLQPERG 728
Query: 2711 KTNKEEHKLQDSVPENKGISLRSRRQNKTEAEQQITEVFVLAERIEINRNEKKPMKTSPE 2770
K E + + + + ++ + E+E +I E + ++ +E +P PE
Sbjct: 729 SPKKCEAEEAEPPAATQPQTSETQTSHLPESE-RIHHTVEEKEEVTMDTSENRPENDVPE 787
Query: 2771 MDIQNPDDGARKPIPRDKVTENKRCLRSARQNESSQPKVAEESGGQKSAKVLMQNQKGKG 2830
+ D + P V + ++ ESS PK + K+ + +
Sbjct: 788 PPMPIADQVSNDDRPEGSVEDEEK-------KESSLPKSFKR-------KISVVSATKGV 833
Query: 2831 EAGNSDSMCLRSRKTKSQPA--ASTLESKSVQRVTRSVKRCAENPKKAEDNVCVKKIRTR 2888
AGNSD+ + + + A A+T + S+ T S+K + K V +
Sbjct: 834 PAGNSDTEGGQPGRKRRWGASTATTQKKPSISITTESLKSLIPDIKPLAGQEAVVDLHAD 893
Query: 2889 SHRDSED 2895
R SED
Sbjct: 894 DSRISED 900
Score = 38.5 bits (88), Expect = 0.097
Identities = 115/624 (18%), Positives = 212/624 (33%), Gaps = 111/624 (17%)
Query: 972 RPQTPKEEAQALEDLTGFKELFQTPGHTEEAVAAGKTTKMPCESSPPESADTPTSTRRQP 1031
RP+T +E + LE G+ T+ E+ A +
Sbjct: 323 RPKTRSQEQEVLE-------------------RGGRFTRSQEEARKSHLARQQQEKEMKT 363
Query: 1032 KTPLEKRDVQKELSALKKLTQTSGETTHTDKVPGGEDKSINAFRE-TAKQKLDPAASVTG 1090
+PLE+ + +E+ + + L + S + + S+ A E TA ++ P +T
Sbjct: 364 TSPLEEEE--REIKSSQGLKEKSKSPSPPRLTEDRKKASLVALPEQTASEEETPPPLLTK 421
Query: 1091 SKRHPK------TKEKAQPLEDLAGLKELFQTPVCTDKPTTHEKTTK--IACRSQPDPVD 1142
P ++E+ +P+E A + +P TD T ++ + P+
Sbjct: 422 EASSPPPHPQLHSEEEIEPMEGPAPPVLIQLSPPNTDADTRELLVSQHTVQLVGGLSPLS 481
Query: 1143 TPTSSKPQSKRSLRKVDVEEEFFALRKRTPSAGKAMHTPKPAVSGEKNIYAFMGTPVQKL 1202
+P+ +K +S KV E ++K T + A +P + +++L
Sbjct: 482 SPSDTKAESPAE--KVPEESVLPLVQKSTLADYSAQKDLEPESDRSAQP---LPLKIEEL 536
Query: 1203 DLTENLTGS--KRRLQTPKEKAQALEDLAGFKELFQTRGHTEESMTNDKTAKVACKSSQP 1260
L + +T K+ KE +A L L Q+ + ++ ++ +S P
Sbjct: 537 ALAKGITEECLKQPSLEQKEGRRASHTLLPSHRLKQSADSSSSRSSSSSSSSSRSRSRSP 596
Query: 1261 DPD----KNPASSKRRLKTSLGKVGVKEELLAVGKLTQTSGETTHTHTEPTGDGKSMKAF 1316
D +P SK+R +G + + + + S K+
Sbjct: 597 DSSGSRSHSPLRSKQRDVAQARTHANPRGRPKMGSRSTSESRSRSRSRSRSASSNSRKSL 656
Query: 1317 MESPKQILDSAASLTGSKRQLRTPKGKSEVPEDLAGFIELFQTPSHTKESMTNEKTTKVS 1376
SP DS+ S T +K P EV +++ + T S ++ +
Sbjct: 657 --SPGVSRDSSTSYTETK----DPSSGQEVATPPVPQLQVCEPKERTSTSSSSVQAR--- 707
Query: 1377 YRASQPDLVDTPTSSKPQPKRSLRKADTEEEFLAFRKQTPSAGKAMHTPKPAVGEEKDIN 1436
R SQP+ + + + QP+R +P +A PA + +
Sbjct: 708 -RLSQPESAEKHVTQRLQPERG----------------SPKKCEAEEAEPPAATQPQTSE 750
Query: 1437 TFLGTPVQKLDQPGNLPGSNRRLQTRKEKAQALEELTGFRELFQTPCTDNPTTDEKTTKK 1496
T Q +LP S R T +EK + + + R P P D+
Sbjct: 751 T----------QTSHLPESERIHHTVEEKEEVTMDTSENRPENDVPEPPMPIADQ----- 795
Query: 1497 ILCKSPQSDPADTPTNTKQRPKRSLKKADVEEEFLAFRKLTPSAGKAMHTPKAAVGEEKD 1556
+ RP+ S++ + +E L PK+ +
Sbjct: 796 --------------VSNDDRPEGSVEDEEKKESSL---------------PKSFKRKISV 826
Query: 1557 INTFVGTPVEKLDLLGNLPGSKRR 1580
++ G P D G PG KRR
Sbjct: 827 VSATKGVPAGNSDTEGGQPGRKRR 850
Score = 36.6 bits (83), Expect = 0.37
Identities = 115/658 (17%), Positives = 220/658 (33%), Gaps = 119/658 (18%)
Query: 531 SKSEETNTEIVECILKRGQKATLLQQRREGEMKEIERPFETYKENIELKENDEKMKAMKR 590
S SEE E K ++++ ++Q R ++ E +P E +E+ E + +++A +
Sbjct: 208 SISEEKGDSDDEKPRKGERRSSRVRQARAAKLSEGSQPAEE-EEDQETPSRNLRVRADRN 266
Query: 591 SRTWGQKCAPMSDLTDLKSLPDTELMKDTARGQNLLQTQDHAKAP-----KSEKGKITKM 645
+T + + + E +D + + Q +AP K E +I ++
Sbjct: 267 LKT------------EEEEEEEEEEEEDDEEEEGDDEGQKSREAPILKEFKEEGEEIPRV 314
Query: 646 PCQSLQPEPINTPTHTKQQLKASLGKVGVKEELLAVGKFTRTSGETTHTHREPAGDGKSI 705
+ + E T + ++ L+ G+FTR+ E +H K +
Sbjct: 315 KPEEMMDERPKTRSQEQEVLERG-------------GRFTRSQEEARKSHLARQQQEKEM 361
Query: 706 RTFKESPKQILDPAARVTGMKKWPRTPKEEAQSLEDLAGFKELFQTPGPSEESMTDEKTT 765
+T SP + EE + ++ G KE ++P P + +K +
Sbjct: 362 KT--TSPLE-------------------EEEREIKSSQGLKEKSKSPSPPRLTEDRKKAS 400
Query: 766 KIACKSPPPESVDTPTSTKQWPKRSLRKADVEEEFLALRKLTPSAGKAMLTPKPAGGDEK 825
+A +TP LT A P P E+
Sbjct: 401 LVALPEQTASEEETPPPL----------------------LTKEASSP--PPHPQLHSEE 436
Query: 826 DIKAFMGTPVQKLDLAGTLPGSKRQLQTPKEKAQALEDLAGFKELFQTPGHTEELVAAGK 885
+I+ + G P QL P A E L HT +LV
Sbjct: 437 EIEP----------MEGPAPPVLIQLSPPNTDADTRELLVS--------QHTVQLVGGLS 478
Query: 886 TTKIPCDSPQSDPVDTPTSTKQRPKRSIRKADVEGELLACRNLMPSAGKAMHTPKPSVGE 945
P D+ P + P ++K+ + + A ++L P + ++ P P E
Sbjct: 479 PLSSPSDTKAESPAEKVPEESVLPL--VQKSTL-ADYSAQKDLEPESDRSAQ-PLPLKIE 534
Query: 946 EKDIIIFVGTPVQKLDLTENLTGSKRR-----PQTPKEEAQALEDLTGFKELFQTPGHTE 1000
E + + K E G + K+ A + + + +
Sbjct: 535 ELALAKGITEECLKQPSLEQKEGRRASHTLLPSHRLKQSADSSSSRSSSSSSSSSRSRSR 594
Query: 1001 EAVAAGKTTKMPCESSPPESADTPTSTRRQPKTPLEKRDVQKELSALKKLTQTSGETTHT 1060
++G + P S + A T + + + R + S + ++++ +
Sbjct: 595 SPDSSGSRSHSPLRSKQRDVAQARTHANPRGRPKMGSRSTSESRSRSRSRSRSASSNSRK 654
Query: 1061 DKVPGGEDKSINAFRETAK---------------QKLDPAASVTGSKRHPKTKEKAQPLE 1105
PG S ++ ET Q +P + S + + +QP
Sbjct: 655 SLSPGVSRDSSTSYTETKDPSSGQEVATPPVPQLQVCEPKERTSTSSSSVQARRLSQPES 714
Query: 1106 DLAGLKELFQTPVCTDKPTTHEKTTKIACRSQPDPVDTPTSSKPQSKRSLRKVDVEEE 1163
+ + Q + K E+ A +QP +T TS P+S+R V+ +EE
Sbjct: 715 AEKHVTQRLQPERGSPKKCEAEEAEPPAA-TQPQTSETQTSHLPESERIHHTVEEKEE 771
>gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f
[Homo sapiens]
Length = 1412
Score = 62.0 bits (149), Expect = 8e-09
Identities = 300/1473 (20%), Positives = 492/1473 (33%), Gaps = 237/1473 (16%)
Query: 1551 VGEEKDINTFVGTPVEKLDLLGNLPGSKRRPQTPKEKAKALEDLAGFKELFQTPGHTEES 1610
V E+ F+ PV LD+ + + + K KA+ L K P T ES
Sbjct: 30 VKEQSGQKCFLAQPVTLLDIYTHWQQTSELGR--KRKAEEDAALQAKKTRVSDPISTSES 87
Query: 1611 MTDDKITEVSCKSPQPDPVKT---------PTSSKQRLKISLGKVGVKEEVLP---VGKL 1658
+++ E P T P+S K++ K K G +P GK
Sbjct: 88 SEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNSMPHPATGKT 147
Query: 1659 TQT--SGKTTQTHRETAGDGKSIKAFKESAKQMLDPANYGTGMERWPRTPKEEAQSLEDL 1716
SGK+ R++A + E+ ++ PA +G + + + S ED
Sbjct: 148 VANLLSGKSP---RKSAEPSANTTLVSETEEEGSVPA-FGAAAKPGMVSAGQADSSSEDT 203
Query: 1717 AGFKELFQTPDHTE-ESTTDDKTTKIACKSPPPESMDTPTSTRRRPKTPLGKRDIVEELS 1775
+ + D T+ E +K ++ S P + +T P P + +
Sbjct: 204 SS------SSDETDVEVKASEKILQVRAASAPAKGTPGKGAT---PAPPGKAGAVASQTK 254
Query: 1776 ALKQLTQTTHTDKVPGDEDKGINVFRETAKQKLDPAASVTGS-----KRQPR-----TPK 1825
A K + + + D ++ + + K S G+ K PR P
Sbjct: 255 AGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPP 314
Query: 1826 GKAQPL--EDLAGLKELFQTPICTDKPTTHEKTTKIACRSPQPDPVGTPTIFKPQSKRSL 1883
GK P + AG +E D ++ E++ Q P G
Sbjct: 315 GKTGPAVAKAQAGKRE-------EDSQSSSEESDSEEEAPAQAKPSG------------- 354
Query: 1884 RKADVEEESLALRKRTPSVGKAMDTPKPAGGDEKDMKAFMGTPVQKLDLPGNLPGSKRWP 1943
KA + A K +P G A P+ G ++ +G + S R
Sbjct: 355 -KAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQ--VGKQEEDSRSSSEESDSDR-- 409
Query: 1944 QTPKEKAQALEDLAGFKELFQTPGTDKPTTDEKTTKIACKSPQPDPVDTPASTKQRPKRN 2003
+A A + A K L ++P +T P P PA+ P
Sbjct: 410 -----EALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPAT----PSAQ 460
Query: 2004 LRKADVEEEFLALRKRTPSAGKAMDTPKPAVSDEKNINTFVETPVQKLDLLGNLPGSKRQ 2063
+ K + + E + S G+ PA EK++ ++ G P K
Sbjct: 461 VGKWEEDSESSSEESSDSSDGEVPTAVAPA--QEKSLGNILQAKPTSSPAKG--PPQKAG 516
Query: 2064 PQTPKEKAEALEDLVGFKELFQTPGHTEESMTDDKITEVSCKSPQPESFKTSRSSKQRLK 2123
P + KAE D + E +D S S + + T+ +K LK
Sbjct: 517 PVAVQVKAEKPMD----------NSESSEESSD------SADSEEAPAAMTAAQAKPALK 560
Query: 2124 IPLVKVDMKEEPLAVSKLTRTSGETTQ------THTEPTGDSKSIKAFKESP------KQ 2171
IP K K+ S TQ T T P G S ++ + P +
Sbjct: 561 IPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSE 620
Query: 2172 ILDPAASVTGSRRQLRTRKEKARALEDLVDFKELFSA---------PGHTEESMTIDKNT 2222
D TG + K + L+ + + PG T ++T K
Sbjct: 621 ESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAE 680
Query: 2223 KIPCKSPPPELTDT--ATSTKRCPKTRPRKEVKEELSAVERLTQTSGQSTHTHKEPASGD 2280
K E +D+ A ++ KT +K + A R G T P
Sbjct: 681 KQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKG----TISAPGKVV 736
Query: 2281 EGIKVLKQRAKKKPNPVEEEPSRRRPRAPKEKAQPLEDLAGFTELSETSGHTQESLTAGK 2340
KQR+ K P P A + P A T +G ++S ++ +
Sbjct: 737 TAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEE 796
Query: 2341 ATKIPCESPPLEVVDTTASTKRHLRT---RVQKVQVKEEPSAVKFTQTSGETTDADKEPA 2397
ES E +T A K +T R KE P G+T + +
Sbjct: 797 ------ESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAG 850
Query: 2398 GEDKGIKALKESAKQTPAPAASVTGSRRRPRAPRESAQAIEDLAGFKDPAAGHTEESMTD 2457
+D + +ES APAA SAQ I+ F DP + T
Sbjct: 851 KQDDSGSSSEESDSDGEAPAAVT------------SAQVIKPPLIFVDPNRSPAGPAATP 898
Query: 2458 DKTTKIPCKSSPELEDTATSSKRRPRTRAQKVEV--KEELLAVGKLTQT-SGETTHTDKE 2514
+ S+P + S+ R + ++ +V + L G T + T H
Sbjct: 899 ---AQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIA 955
Query: 2515 PVGEGKGTKAFKQPAK----RKLDAEDVIGSRRQPRAPKEKAQPLEDLASFQELSQTPGH 2570
P G + K+ ++ +K + S++ P + L+ LA +Q P
Sbjct: 956 PKASMAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVA 1015
Query: 2571 TEELANGAADSFTSAPKQTPDSGKPLKISRRVLRAPKVEPVGDVVSTRDPVKSQSKSNTS 2630
+ ++G + + P +P S LR PK+ V +T+ P S ++S
Sbjct: 1016 RTQPSSGVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQ--ATKAPESSDDSEDSS 1073
Query: 2631 LPPLPFKRGGGKDG-SVTGTKRLRCMPAP-----EEIVEELPA--SKKQRVAPR---ARG 2679
G +DG G K + P E +VEE A S+ VAP G
Sbjct: 1074 ----DSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETLVEETAAESSEDDVVAPSQSLLSG 1129
Query: 2680 KSSEPVVIMKRSLRTSAKRIEPAEELNS----NDMKTNKEEHKLQDSV----PENKG--- 2728
+ + + +++ + ++S D K+E K Q + P+ G
Sbjct: 1130 YMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEA 1189
Query: 2729 ----ISLRSRRQNK---------------------------TEAEQQITEVFVLAERIEI 2757
+SR+ K EA+ Q + V VL E +E
Sbjct: 1190 ASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQ 1249
Query: 2758 NRNEKKPMKTSPEMDIQNPDDGARK-----PIPRDKVTENKRCLRSARQNES--SQPKVA 2810
R KK + T+ E + + RK P R ++ K+ L + E+ S K +
Sbjct: 1250 ER--KKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSPEKTS 1307
Query: 2811 EESGG---QKSAKVLMQNQKGKGEAGNSDSMCLRSRKTKSQPAASTLES------KSVQR 2861
S G + A ++ +KGKG G+ + + + Q T+E KS +
Sbjct: 1308 TTSKGKAKRDKASGDVKEKKGKGSLGSQGAK--DEPEEELQKGMGTVEGGDQSNPKSKKE 1365
Query: 2862 VTRSVKRCAENPKKAEDNVCVKKIRTRSHRDSE 2894
+S KR + KK + KK + S +DSE
Sbjct: 1366 KKKSDKRKKDKEKKEKK----KKAKKASTKDSE 1394
>gi|14790190 spen homolog, transcriptional regulator [Homo sapiens]
Length = 3664
Score = 61.6 bits (148), Expect = 1e-08
Identities = 127/534 (23%), Positives = 198/534 (37%), Gaps = 64/534 (11%)
Query: 2203 KELFSAPGHTEESMTIDKNTKIPCKSPPPELTDTATSTKRCPKTRPRKEVKEELSAVERL 2262
KE P E+ + + K P +P + ++ T P P V SA L
Sbjct: 1598 KEKDQKPKEVEKQEDTENHPKTPESAPENKDSELKTPPSVGP---PSVTVVTLESAPSAL 1654
Query: 2263 TQTSGQST--------HTHKEPASGDEGIKVLKQRAKKKPNPVEE-EPSRRRPRAPKEKA 2313
+T+G T EPA+ E K + A P PVE+ E P A +K
Sbjct: 1655 EKTTGDKTVEAPLVTEEKTVEPATVSEEAKPASEPA---PAPVEQLEQVDLPPGADPDKE 1711
Query: 2314 QPLEDLAGFTELSETSGHTQESLTAGKATKIPCESPPLEVVDTTASTKRHLRTRVQKVQV 2373
+ AG E S SG L A T S VD + + L QK +
Sbjct: 1712 AAMMP-AGVEEGS--SGDQPPYLDAKPPTPGASFSQAESNVDPEPDSTQPLSKPAQKSEE 1768
Query: 2374 KEEPSAVKFTQTSGETTDADKE---------PAGED---------KGIKALKESAKQTPA 2415
EP A K T+ DA+++ PA ED K K K +TP
Sbjct: 1769 ANEPKAEKPDATADAEPDANQKAEAAPESQPPASEDLEVDPPVAAKDKKPNKSKRSKTPV 1828
Query: 2416 PAASVT-----GSRRRPRAPRESAQAIEDLAGFKDPAAGHTEESMTDDKTTKIPCKSSPE 2470
AA+V+ +R+ R RE + G A E M +K T+ K+S
Sbjct: 1829 QAAAVSIVEKPVTRKSERIDREKLKRSNSPRG---EAQKLLELKMEAEKITRTASKNSAA 1885
Query: 2471 LEDTATSSKRRPRTRAQKVEVKEELLAVGKLTQTSGETTHTDKEPVGEGKGTKAFKQPAK 2530
D P +R ++ V+ +G E KEPV + + T+ K+ +
Sbjct: 1886 --DLEHPEPSLPLSRTRRRNVRSVYATMG-----DHENRSPVKEPVEQPRVTR--KRLER 1936
Query: 2531 RKLDAEDVIGSRRQPRAPKEKAQPLEDLASFQELSQTPGHTEELANGAADSFTSAPKQTP 2590
+A V + R+ R PK + + E+ + ++ P T + G + ++T
Sbjct: 1937 ELQEAAAVPTTPRRGRPPKTRRRADEEE---ENEAKEPAETLKPPEGWR---SPRSQKTA 1990
Query: 2591 DSGKPLKISRRVLRAPKVEPVGDVVSTRDPVKSQSKSNTSLPPLPFKRGGG---KDGSVT 2647
G P ++ PKV+ +T + K ++ P + G +D
Sbjct: 1991 AGGGPQ--GKKGKNEPKVDATRPEATTEVGPQIGVKESSMEPKAAEEEAGSEQKRDRKDA 2048
Query: 2648 GTKRLRCMPAPEEIVEELPASKKQRVAPRARGKSSEPVVIMKRSLRTSAKRIEP 2701
GT + AP E+VE+ PA +K + R R ++S V SL+ + P
Sbjct: 2049 GTDKNPPETAPVEVVEKKPAPEKNSKSKRGRSRNSRLAVDKSASLKNVDAAVSP 2102
Score = 55.5 bits (132), Expect = 8e-07
Identities = 177/928 (19%), Positives = 313/928 (33%), Gaps = 144/928 (15%)
Query: 1775 SALKQLTQTTHTDKVPGDEDKGINVFRETAKQKLDPAASVTGSKRQPRTPKGKAQPLEDL 1834
S +LT+ +K + K + +T P ++ + +TP P +
Sbjct: 1585 SRFMELTRMQQKEKEKDQKPKEVEKQEDTENHPKTPESAPENKDSELKTPPSVGPPSVTV 1644
Query: 1835 AGLKELFQTPICTDKPTTHEKTTKIACRSPQPDPVGTPTIFKP--QSKRSLRKADVEEES 1892
L+ P+ EKTT G T+ P ++++ A V EE+
Sbjct: 1645 VTLESA---------PSALEKTT------------GDKTVEAPLVTEEKTVEPATVSEEA 1683
Query: 1893 LALRKRTPS-VGKAMDTPKPAGGDEKDMKAFMGTPVQKLDLPGNLPGSKRWPQTPKEKAQ 1951
+ P+ V + P G D A M V++ P P TP
Sbjct: 1684 KPASEPAPAPVEQLEQVDLPPGADPDKEAAMMPAGVEEGSSGDQPPYLDAKPPTPGASFS 1743
Query: 1952 ALEDLAGFKELFQTPGTDKPTTDEKTTKIACKSPQPDPVDTPASTKQRPKRNLRKADVEE 2011
E + P + +P + P+ + D A + D +
Sbjct: 1744 QAES-----NVDPEPDSTQPLSKPAQKSEEANEPKAEKPDATADAEP---------DANQ 1789
Query: 2012 EFLALRKRTPSAGKAMDTPKPAVSDEKNINTFV--ETPVQKLDL-LGNLPGSKRQPQTPK 2068
+ A + P A + ++ P + +K N +TPVQ + + P +++ + +
Sbjct: 1790 KAEAAPESQPPASEDLEVDPPVAAKDKKPNKSKRSKTPVQAAAVSIVEKPVTRKSERIDR 1849
Query: 2069 EKAEALEDLVGFKELFQTPGHTEESMTDDKITEVSCKSPQPESFKTSRSSKQRLKIPLVK 2128
EK + G + E M +KIT + K+ +
Sbjct: 1850 EKLKRSNSPRGEAQKL-----LELKMEAEKITRTASKNSAADL----------------- 1887
Query: 2129 VDMKEEPLAVSKLTRTSGETTQTHTEPTGDSKSIKAFKESPKQI----------LDPAAS 2178
E P L+RT ++ GD ++ KE +Q L AA+
Sbjct: 1888 ----EHPEPSLPLSRTRRRNVRSVYATMGDHENRSPVKEPVEQPRVTRKRLERELQEAAA 1943
Query: 2179 VTGSRRQLRTRKEKARALEDLVDFKELFSAPGHTEESMTIDKNTKIPCKSPPP------E 2232
V + R+ R K + RA E+ + + + E ++ K P E
Sbjct: 1944 VPTTPRRGRPPKTRRRADEEEENEAKEPAETLKPPEGWRSPRSQKTAAGGGPQGKKGKNE 2003
Query: 2233 LTDTATSTKRCPKTRPRKEVKEELSAVERLTQTSGQSTHTHKEPASGDEG------IKVL 2286
AT + + P+ VKE + + +G ++ A D+ ++V+
Sbjct: 2004 PKVDATRPEATTEVGPQIGVKESSMEPKAAEEEAGSEQKRDRKDAGTDKNPPETAPVEVV 2063
Query: 2287 KQRAKKKPNPVEEEPSRRRPRAPKEKAQPLEDL------------AGFTELSETSGHTQE 2334
+++ + N + R R +K+ L+++ AG E + ++
Sbjct: 2064 EKKPAPEKNSKSKRGRSRNSRLAVDKSASLKNVDAAVSPRGAAAQAGERESGVVAVSPEK 2123
Query: 2335 SLTAGKATKIPCE--SPPL------EVVDTTASTKRHLRTRVQKVQVKEEP--SAVKFTQ 2384
S + K + + S P+ E D +AS T++ K E+ K +
Sbjct: 2124 SESPQKEDGLSSQLKSDPVDPDKEPEKEDVSASGPSPEATQLAKQMELEQAVEHIAKLAE 2183
Query: 2385 TSGETT---DADKEPAGEDKGIKALKESAKQTPAPAASVTGS--------RRRPRAPRES 2433
S DA + A ED+ A + S + A S+ P P ES
Sbjct: 2184 ASASAAYKADAPEGLAPEDRDKPAHQASETELAAAIGSIINDISGEPENFPAPPPYPGES 2243
Query: 2434 AQAIEDLAGFKDPAAGHTEESMTDDKTTKIPCKSSPELEDTATSSKRRPRTRAQKVEVKE 2493
++ AG + A +EE M D+ S LE A + RP A
Sbjct: 2244 QTDLQPPAGAQ--ALQPSEEGMETDEAV------SGILETEAATESSRPPVNAPDPSAGP 2295
Query: 2494 ELLAVGKLTQTSGETTHTDKEPVGEGKGTKAFKQPAKRK-LDAEDVIGSRRQPRAPKEKA 2552
+ S ET+H+ V E KG+K + RK + SRR+ K+
Sbjct: 2296 T--DTKEARGNSSETSHS----VPEAKGSKEVEVTLVRKDKGRQKTTRSRRKRNTNKKVV 2349
Query: 2553 QPLEDLASFQELSQTPGHTEELANGAADSFTSAPKQT-----PDSGKPLKISRRVLRAPK 2607
P+E + E +Q G + G AP++ P S P + + + P
Sbjct: 2350 APVE--SHVPESNQAQGESPAANEGTTVQHPEAPQEEKQSEKPHSTPPQSCTSDLSKIPS 2407
Query: 2608 VEPVGDVVSTRDPVKSQSKSNTSLPPLP 2635
E +S + +++ LPP P
Sbjct: 2408 TENSSQEISVEERTPTKASVPPDLPPPP 2435
Score = 50.4 bits (119), Expect = 2e-05
Identities = 209/1012 (20%), Positives = 346/1012 (34%), Gaps = 174/1012 (17%)
Query: 1067 EDKSINAFRETAKQKLDPAASVTGSKRHPKTKEKAQPLEDLAGL----KELFQTPVCTDK 1122
ED + R KQ + A S T S + P ++ +E L + KE Q P +K
Sbjct: 1551 EDSDFISGRIYGKQTSEGANSTTDSIQEPVVLFHSRFME-LTRMQQKEKEKDQKPKEVEK 1609
Query: 1123 PT---THEKTTKIACRSQPDPVDTPTSSKPQSKRSLRKVDVEEEFFALRKRTPSAGKAMH 1179
H KT + A ++ + TP S P S + V +E AL K T K +
Sbjct: 1610 QEDTENHPKTPESAPENKDSELKTPPSVGPPS---VTVVTLESAPSALEKTT--GDKTVE 1664
Query: 1180 TPKPAVSGEKNIYAFMGTPVQKLDLTENLTGSKRRLQTPKEKAQALEDLAGF---KELFQ 1236
P V+ EK V+ ++E + P E+ + ++ G KE
Sbjct: 1665 AP--LVTEEKT--------VEPATVSEEAKPASEPAPAPVEQLEQVDLPPGADPDKEAAM 1714
Query: 1237 TRGHTEESMTNDKTAKVACKSSQPDPDKNPASSKRRLKTSLGKVGVKEELLAVGKLTQTS 1296
EE + D+ + K P + A S + + + K Q S
Sbjct: 1715 MPAGVEEGSSGDQPPYLDAKPPTPGASFSQAESNVDPEP--------DSTQPLSKPAQKS 1766
Query: 1297 GETTHTHTEPTGDGKSMKAFMESPKQILDSAASLTGSKRQLRTPKGKSEVPEDLAGFIEL 1356
E EP E P D A +++ P+ + EDL
Sbjct: 1767 EEAN----EPKA---------EKPDATAD--AEPDANQKAEAAPESQPPASEDLE----- 1806
Query: 1357 FQTPSHTKESMTNE-KTTKVSYRASQPDLVDTPTSSKPQPKRSLRKADTEEEFLAFRKQT 1415
P K+ N+ K +K +A+ +V+ P + K + + D E+ ++
Sbjct: 1807 VDPPVAAKDKKPNKSKRSKTPVQAAAVSIVEKPVTRKSE------RIDREK----LKRSN 1856
Query: 1416 PSAGKAMHTPKPAVGEEKDINTFLGTPVQKLDQPG-NLPGSNRRLQTRKEKAQALEELTG 1474
G+A + + EK T L+ P +LP S +TR+ +++ G
Sbjct: 1857 SPRGEAQKLLELKMEAEKITRTASKNSAADLEHPEPSLPLS----RTRRRNVRSVYATMG 1912
Query: 1475 FRELFQTPCTDNPTTDEKTTKKILCKSPQSDPADTPTNTKQRPKRSLKKADVEEEFLA-- 1532
E ++P + P + T+K L + Q A T + RP ++ ++AD EEE A
Sbjct: 1913 DHEN-RSPVKE-PVEQPRVTRKRLERELQEAAAVPTTPRRGRPPKTRRRADEEEENEAKE 1970
Query: 1533 -FRKLTPSAG-KAMHTPKAAVG------EEKDINTFVGTPVEKLDLLGNLPGSKRRPQTP 1584
L P G ++ + K A G + K+ T E +G G K P
Sbjct: 1971 PAETLKPPEGWRSPRSQKTAAGGGPQGKKGKNEPKVDATRPEATTEVGPQIGVKESSMEP 2030
Query: 1585 KEKAKALEDLAGFKELFQTPGHTEESMTDDKITEVSCKSPQPDPVKTPTSSKQRLKISLG 1644
K A E+ ++ + T+++ + EV K P P+ K S + R + S
Sbjct: 2031 K---AAEEEAGSEQKRDRKDAGTDKNPPETAPVEVVEKKPAPE--KNSKSKRGRSRNSRL 2085
Query: 1645 KVGVKEEVLPVGKLTQTSGKTTQTHRETAG-----DGKSIKAFKE---SAKQMLDPANYG 1696
V + V G Q +G KS KE S++ DP +
Sbjct: 2086 AVDKSASLKNVDAAVSPRGAAAQAGERESGVVAVSPEKSESPQKEDGLSSQLKSDPVDPD 2145
Query: 1697 TGMERWPRTPKEEAQSLEDLAGFKELFQTPDHTEESTTDDKTTKIACKSP---PPESMDT 1753
E+ + + LA EL Q +H + + +P PE D
Sbjct: 2146 KEPEKEDVSASGPSPEATQLAKQMELEQAVEHIAKLAEASASAAYKADAPEGLAPEDRDK 2205
Query: 1754 PTSTRRRPKTPLGKRDIVEELS-------ALKQLTQTTHTDKVPG-------------DE 1793
P + I+ ++S A + TD P +
Sbjct: 2206 PAHQASETELAAAIGSIINDISGEPENFPAPPPYPGESQTDLQPPAGAQALQPSEEGMET 2265
Query: 1794 DKGINVFRETAK---------QKLDPAASVTGSKRQPRTPKGKAQPLEDLAGLKELFQTP 1844
D+ ++ ET DP+A T +K + + + G KE+ T
Sbjct: 2266 DEAVSGILETEAATESSRPPVNAPDPSAGPTDTKEARGNSSETSHSVPEAKGSKEVEVTL 2325
Query: 1845 ICTDKPTTHEKTTKIACRSPQPDPVGTPTIFKPQSKRSLRKADVEEESLA-LRKRTPSVG 1903
+ DK +KTT RS RK + ++ +A + P
Sbjct: 2326 VRKDK--GRQKTT-----------------------RSRRKRNTNKKVVAPVESHVPESN 2360
Query: 1904 KAMDTPKPAGGDEKDMKAFMGTPVQKLDLPGNLPGSKRWPQTPKEKAQALEDLAGFKELF 1963
+A PA + GT VQ + P S++ TP + + +L
Sbjct: 2361 QAQG-ESPAANE--------GTTVQHPEAPQEEKQSEKPHSTPPQSCTS--------DLS 2403
Query: 1964 QTPGTDKP----TTDEKTTKIACKSPQPDPVDTPASTKQRPKRNLRKADVEE 2011
+ P T+ + +E+T A P P PA + P+ R + E
Sbjct: 2404 KIPSTENSSQEISVEERTPTKASVPPDLPPPPQPAPVDEEPQARFRVHSIIE 2455
Score = 47.4 bits (111), Expect = 2e-04
Identities = 132/667 (19%), Positives = 242/667 (36%), Gaps = 93/667 (13%)
Query: 2223 KIPCKSPPPELTDTATSTKRCPKTRPRKEVKEELSAVERLTQTSGQSTHTHKEPASGDEG 2282
++P S + ++ + C P + K + S +ER T+ +P +
Sbjct: 746 RLPSDSERRLYSRSSDRSGSCSSLSPPRYEKLDKSRLERYTKNEKTDKERTFDPERVERE 805
Query: 2283 IKVLKQRAKKKPNPVEEEPSRRRPRAPKEKAQPLE-DLAGFTELSETSGHTQESLTAGKA 2341
++++ K+K + + +R+ + +Q E D E S + L+ KA
Sbjct: 806 RRLIR---KEKVEKDKTDKQKRKGKVHSPSSQSSETDQENEREQSPEKPRSCNKLSREKA 862
Query: 2342 TKIPCESPPLEVVDTTASTKRHLR-------TRVQKVQVKEEPSAVKFTQTSGETTDADK 2394
K LE++ T+ + T V+K++ K + VK + + +
Sbjct: 863 DKEGIAKNRLELMPCVVLTRVKEKEGKVIDHTPVEKLKAKLDNDTVKSSALDQKLQVSQT 922
Query: 2395 EPAGEDKG------IKALKESAKQTPAPAASVTGSRR-----RPRAPRESAQAIEDLAGF 2443
EPA D +K KE + G + +P P + A+ DL
Sbjct: 923 EPAKSDLSKLESVRMKVPKEKGLSSHVEVVEKEGRLKARKHLKPEQPADGVSAV-DLEKL 981
Query: 2444 KDPAAGHTEESMTDDKTTKIPCKSSPELEDTATSSKRRPRTRAQKV-----------EVK 2492
+ + ++ +K KSSPE+ED SK++P +++V V+
Sbjct: 982 EARKRRFADSNLKAEKQKPEVKKSSPEMEDARVLSKKQPDVSSREVILLREGEAERKPVR 1041
Query: 2493 EELLA--VGKLTQTSGETTHTDKE-------PVGEGKGTKAFKQPAKRKLDAEDVIGSRR 2543
+E+L K+ T + K+ VG G + Q +L E V
Sbjct: 1042 KEILKRESKKIKLDRLNTVASPKDCQELASISVGSGSRPSSDLQARLGELAGESVENQEV 1101
Query: 2544 QPRAPKEKAQPLEDLASFQELSQTPGHTEELANGAADSFTSAPKQTPDSGKPLKISRRVL 2603
Q + P L+ L + Q P + N + S +TP+ + S V
Sbjct: 1102 QSKKPIPSKPQLKQLQVLDD--QGPEREDVRKN-----YCSLRDETPERKSGQEKSHSVN 1154
Query: 2604 RAPKVE-PVGDVVSTRDPVK-SQSKSNTSLPPLPFKRGGGKDGSVTGTKRLRCM----PA 2657
K+ + S R ++ S+ K + ++ G V +R +
Sbjct: 1155 TEEKIGIDIDHTQSYRKQMEQSRRKQQMEMEIAKSEKFGSPKKDVDEYERRSLVHEVGKP 1214
Query: 2658 PEEIVEELPASKKQRV--------APRARGKSSEPVVIMKRSLRTSAKRI-------EPA 2702
P+++ ++ P SKK+R+ R R S I + S RT E
Sbjct: 1215 PQDVTDDSPPSKKKRMDHVDFDICTKRERNYRSSR-QISEDSERTGGSPSVRHGSFHEDE 1273
Query: 2703 EELNSNDMKTNKEEHKLQDSVPENKGISLR-----------SRRQNKTEAEQQITEVFVL 2751
+ + S + + K K+ + V I++R SRR+ A+ ++ VL
Sbjct: 1274 DPIGSPRLLSVKGSPKVDEKVLPYSNITVREESLKFNPYDSSRREQM--ADMAKIKLSVL 1331
Query: 2752 AERIEINRNEKKPMKTSPEMDIQNPDDGARKPIPRDKVTENKRCLRSARQNESSQPKVAE 2811
E+NR + + + + D+ P+ I RD + KR +R E P ++
Sbjct: 1332 NSEDELNRWDSQMKQDAGRFDVSFPN----SIIKRDSL--RKRSVRDLEPGE--VPSDSD 1383
Query: 2812 ESGGQKS 2818
E G KS
Sbjct: 1384 EDGEHKS 1390
Score = 35.0 bits (79), Expect = 1.1
Identities = 170/872 (19%), Positives = 308/872 (35%), Gaps = 126/872 (14%)
Query: 419 NSENLLGKQFQGTDSGEEPLLPTSESFGGNVFFSAQNAAKQPSDKCSAS------PPLRR 472
+S L K Q ++ EP ++ + Q A P + AS PP+
Sbjct: 1754 DSTQPLSKPAQKSEEANEPKAEKPDATADAEPDANQKAEAAPESQPPASEDLEVDPPVAA 1813
Query: 473 QCIRENGNV-AKTPRNTYKMTSLETKTSDTETEPSKTVSTANRSGRSTEFRNIQKLPVES 531
+ + N + +KTP ++ +E + + + S R E + + +L +E+
Sbjct: 1814 KDKKPNKSKRSKTPVQAAAVSIVEKPVTRKSERIDREKLKRSNSPRG-EAQKLLELKMEA 1872
Query: 532 -KSEETNTEIVECILKRGQKATLLQQRREGEMKEIERPFETYKENIELKENDEKMKAMKR 590
K T ++ L+ + + L + R ++ + ++ +KE E+ + ++
Sbjct: 1873 EKITRTASKNSAADLEHPEPSLPLSRTRRRNVRSVYATMGDHENRSPVKEPVEQPRVTRK 1932
Query: 591 SRTWGQKCAPMSDLTDLKSLP-------DTELMKDTARGQNLLQTQDHAKAPKSEKGKIT 643
+ A T + P D E + L+ + ++P+S+K
Sbjct: 1933 RLERELQEAAAVPTTPRRGRPPKTRRRADEEEENEAKEPAETLKPPEGWRSPRSQKTAAG 1992
Query: 644 KMPCQSLQPEPINTPTHTKQQLKASLG-KVGVKEELLAVGKFTRTSGETTHTHREPAGDG 702
P Q + + T+ + +G ++GVKE + +G R+ AG
Sbjct: 1993 GGP-QGKKGKNEPKVDATRPEATTEVGPQIGVKESSMEPKAAEEEAGSEQKRDRKDAGTD 2051
Query: 703 KS------IRTFKESPKQILDPAARVTGMKKWPRTPKEEAQSLEDL------------AG 744
K+ + ++ P + ++ G + R +++ SL+++ AG
Sbjct: 2052 KNPPETAPVEVVEKKPAPEKNSKSK-RGRSRNSRLAVDKSASLKNVDAAVSPRGAAAQAG 2110
Query: 745 FKELFQTPGPSEESMTDEKTTKIAC--KSPP------PESVDTPTSTKQWPKRSLRKA-D 795
+E E+S + +K ++ KS P PE D S L K +
Sbjct: 2111 ERESGVVAVSPEKSESPQKEDGLSSQLKSDPVDPDKEPEKEDVSASGPSPEATQLAKQME 2170
Query: 796 VEEEFLALRKLTPSAGKAM--------LTP----KPAG-GDEKDIKAFMGTPVQKLDLAG 842
+E+ + KL ++ A L P KPA E ++ A +G+ + D++G
Sbjct: 2171 LEQAVEHIAKLAEASASAAYKADAPEGLAPEDRDKPAHQASETELAAAIGSIIN--DISG 2228
Query: 843 T---------LPGSKRQLQTPKEKAQALEDLAGFKELFQTPGHTEELVAAGKTTKIPCDS 893
PG + P AQAL+ E + E AA ++++ P ++
Sbjct: 2229 EPENFPAPPPYPGESQTDLQPPAGAQALQPSEEGMETDEAVSGILETEAATESSRPPVNA 2288
Query: 894 PQSDPVDTPTSTKQRPKRSIRKADVEGELLACRNLMPSAGKAMHTPKPSVGEEKDIIIFV 953
P DP PT TK+ + G + T SV E K
Sbjct: 2289 P--DPSAGPTDTKE-----------------------ARGNSSETSH-SVPEAKGSKEVE 2322
Query: 954 GTPVQKLDLTENLTGSKRRPQTPKEEAQALEDLTGFKELFQ--TPGHTE-------EAVA 1004
T V+K + T S+R+ T K+ +E Q +P E EA
Sbjct: 2323 VTLVRKDKGRQKTTRSRRKRNTNKKVVAPVESHVPESNQAQGESPAANEGTTVQHPEAPQ 2382
Query: 1005 AGKTTKMPCESSPPESADTPTSTRRQPKTPLEKRDVQKELSALKKLTQTSGETTHTDKVP 1064
K ++ P S+PP+S + S + P T +++ E K + P
Sbjct: 2383 EEKQSEKP-HSTPPQSCTSDLS--KIPSTENSSQEISVEERTPTKASVPPDLPPPPQPAP 2439
Query: 1065 GGEDKSINAFRETAKQKLDPAA-----SVTGSKRHPKTKEKAQPLEDLAGLKELFQTPVC 1119
E+ FR + + DP S+ T K P G+
Sbjct: 2440 VDEEPQAR-FRVHSIIESDPVTPPSDPSIPIPTLPSVTAAKLSPPVASGGIPHQSPPTKV 2498
Query: 1120 TDKPTTHEKTTKIACRSQPDPVDTPTSSKPQSKRSLRKVDVEEEFFALRKRTP------- 1172
T+ T E+ + S P DT S S +LRK+ ++ ++ + T
Sbjct: 2499 TEWITRQEEPRAQSTPSPALPPDTKASDVDTSSSTLRKILMDPKYVSATSVTSTSVTTAI 2558
Query: 1173 ----SAGKAMH-TPKPAVSGEKNIYAFMGTPV 1199
SA +H P P V +K + PV
Sbjct: 2559 AEPVSAAPCLHEAPPPPVDSKKPLEEKTAPPV 2590
Score = 34.7 bits (78), Expect = 1.4
Identities = 42/190 (22%), Positives = 82/190 (43%), Gaps = 31/190 (16%)
Query: 2675 PRARGKSSEPVVIMKRSLRTSAKRIEPAEELNSNDMKTNKEEHKLQDSVPENKGISLRSR 2734
P+ +G SS V+ K + K ++P + + S + + + R R
Sbjct: 940 PKEKGLSSHVEVVEKEGRLKARKHLKPEQPADGV-------------SAVDLEKLEARKR 986
Query: 2735 R--QNKTEAEQQITEVFVLAERIEINR--NEKKPMKTSPEMDIQNPDDGARKPIPRDKVT 2790
R + +AE+Q EV + +E R ++K+P +S E+ + + RKP+ ++ +
Sbjct: 987 RFADSNLKAEKQKPEVKKSSPEMEDARVLSKKQPDVSSREVILLREGEAERKPVRKEILK 1046
Query: 2791 ENKRCLRSARQNESSQPKVAEESGGQKSAKVLMQNQKGKGEAGNSDSMCLRSRKTKSQPA 2850
+ ++ R N + PK +E L G G +SD L++R + A
Sbjct: 1047 RESKKIKLDRLNTVASPKDCQE---------LASISVGSGSRPSSD---LQAR--LGELA 1092
Query: 2851 ASTLESKSVQ 2860
++E++ VQ
Sbjct: 1093 GESVENQEVQ 1102
Score = 34.3 bits (77), Expect = 1.8
Identities = 88/445 (19%), Positives = 157/445 (35%), Gaps = 52/445 (11%)
Query: 1302 THTEPTGD--GKSMKAFMESPKQI-LDSAASLTGSKRQLRTPKG-KSEVPEDLAGFIELF 1357
+ TEP K M+ PK+ L S + + +L+ K K E P D ++L
Sbjct: 920 SQTEPAKSDLSKLESVRMKVPKEKGLSSHVEVVEKEGRLKARKHLKPEQPADGVSAVDLE 979
Query: 1358 QTPSHTK---ESMTNEKTTKVSYRASQPDLVDTPTSSKPQPKRSLRKADTEEEFLAFRKQ 1414
+ + + +S + K + S P++ D SK QP S R+ E A RK
Sbjct: 980 KLEARKRRFADSNLKAEKQKPEVKKSSPEMEDARVLSKKQPDVSSREVILLREGEAERKP 1039
Query: 1415 TPSAGKAMHTPK------PAVGEEKDINTFLGTPVQKLDQP--------GNLPGSNRRLQ 1460
+ K V KD V +P G L G +
Sbjct: 1040 VRKEILKRESKKIKLDRLNTVASPKDCQELASISVGSGSRPSSDLQARLGELAGES---- 1095
Query: 1461 TRKEKAQALEELTGFRELFQTPCTDNPTTDEKTTKKILCKSPQSDPADTPTNTKQRPKRS 1520
++ Q+ + + +L Q D+ + + +K C P K +
Sbjct: 1096 VENQEVQSKKPIPSKPQLKQLQVLDDQGPEREDVRKNYCSLRDETPERKSGQEKSHSVNT 1155
Query: 1521 LKKADVE-EEFLAFRK-LTPSAGKAMHTPKAAVGE-----EKDINTF--------VGTPV 1565
+K ++ + ++RK + S K + A E +KD++ + VG P
Sbjct: 1156 EEKIGIDIDHTQSYRKQMEQSRRKQQMEMEIAKSEKFGSPKKDVDEYERRSLVHEVGKPP 1215
Query: 1566 EKLDLLGNLPGSKRRPQTPKEKAKALEDLAGFKELFQTPGHTEESMTDDKITEVSCKSPQ 1625
+ D+ + P SK++ + + ++ Q +E + + S +
Sbjct: 1216 Q--DVTDDSPPSKKKRMDHVDFDICTKRERNYRSSRQISEDSERTGGSPSVRHGSFHEDE 1273
Query: 1626 PDPVKTPTSSKQRLKISLGKVGVKEEVLPVGKLTQTSGKTTQTHRETAGDGKSIKAFKES 1685
DP+ +P RL G V E+VLP +T ++ + D + +
Sbjct: 1274 -DPIGSP-----RLLSVKGSPKVDEKVLPYSNITVRE----ESLKFNPYDSSRREQMADM 1323
Query: 1686 AKQMLDPANYGTGMERWPRTPKEEA 1710
AK L N + RW K++A
Sbjct: 1324 AKIKLSVLNSEDELNRWDSQMKQDA 1348
>gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b [Homo
sapiens]
Length = 1411
Score = 61.6 bits (148), Expect = 1e-08
Identities = 301/1472 (20%), Positives = 493/1472 (33%), Gaps = 236/1472 (16%)
Query: 1551 VGEEKDINTFVGTPVEKLDLLGNLPGSKRRPQTPKEKAKALEDLAGFKELFQTPGHTEES 1610
V E+ F+ PV LD+ + + + K KA+ L K P T ES
Sbjct: 30 VKEQSGQKCFLAQPVTLLDIYTHWQQTSELGR--KRKAEEDAALQAKKTRVSDPISTSES 87
Query: 1611 MTDDKITEVSCKSPQPDPVKT---------PTSSKQRLKISLGKVGVKEEVLP---VGKL 1658
+++ E P T P+S K++ K K G +P GK
Sbjct: 88 SEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNSMPHPATGKT 147
Query: 1659 TQT--SGKTTQTHRETAGDGKSIKAFKESAKQMLDPANYGTGMERWPRTPKEEAQSLEDL 1716
SGK+ R++A + E+ ++ PA +G + + + S ED
Sbjct: 148 VANLLSGKSP---RKSAEPSANTTLVSETEEEGSVPA-FGAAAKPGMVSAGQADSSSEDT 203
Query: 1717 AGFKELFQTPDHTE-ESTTDDKTTKIACKSPPPESMDTPTSTRRRPKTPLGKRDIVEELS 1775
+ + D T+ E +K ++ S P + +T P P + +
Sbjct: 204 SS------SSDETDVEVKASEKILQVRAASAPAKGTPGKGAT---PAPPGKAGAVASQTK 254
Query: 1776 ALKQLTQTTHTDKVPGDEDKGINVFRETAKQKLDPAASVTGS-----KRQPR-----TPK 1825
A K + + + D ++ + + K S G+ K PR P
Sbjct: 255 AGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPP 314
Query: 1826 GKAQPL--EDLAGLKELFQTPICTDKPTTHEKTTKIACRSPQPDPVGTPTIFKPQSKRSL 1883
GK P + AG +E D ++ E++ Q P G
Sbjct: 315 GKTGPAVAKAQAGKRE-------EDSQSSSEESDSEEEAPAQAKPSG------------- 354
Query: 1884 RKADVEEESLALRKRTPSVGKAMDTPKPAGGDEKDMKAFMGTPVQKLDLPGNLPGSKRWP 1943
KA + A K +P G A P+ G ++ +G + S R
Sbjct: 355 -KAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQ--VGKQEEDSRSSSEESDSDR-- 409
Query: 1944 QTPKEKAQALEDLAGFKELFQTPGTDKPTTDEKTTKIACKSPQPDPVDTPASTKQRPKRN 2003
+A A + A K L ++P +T P P PA+ P
Sbjct: 410 -----EALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPAT----PSAQ 460
Query: 2004 LRKADVEEEFLALRKRTPSAGKAMDTPKPAVSDEKNINTFVETPVQKLDLLGNLPGSKRQ 2063
+ K + + E + S G+ PA EK++ ++ G P K
Sbjct: 461 VGKWEEDSESSSEESSDSSDGEVPTAVAPA--QEKSLGNILQAKPTSSPAKG--PPQKAG 516
Query: 2064 PQTPKEKAEALEDLVGFKELFQTPGHTEESMTDDKITEVSCKSPQPESFKTSRSSKQRLK 2123
P + KAE D + E +D S S + + T+ +K LK
Sbjct: 517 PVAVQVKAEKPMD----------NSESSEESSD------SADSEEAPAAMTAAQAKPALK 560
Query: 2124 IPLVKVDMKEEPLAVSKLTRTSGETTQ------THTEPTGDSKSIKAFKESP------KQ 2171
IP K K+ S TQ T T P G S ++ + P +
Sbjct: 561 IPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSE 620
Query: 2172 ILDPAASVTGSRRQLRTRKEKARALEDLVDFKELFSA---------PGHTEESMTIDKNT 2222
D TG + K + L+ + + PG T ++T K
Sbjct: 621 ESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAE 680
Query: 2223 KIPCKSPPPELTDT--ATSTKRCPKTRPRKEVKEELSAVERLTQTSGQSTHTHKEPASGD 2280
K E +D+ A ++ KT +K + A R G T P
Sbjct: 681 KQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKG----TISAPGKVV 736
Query: 2281 EGIKVLKQRAKKKPNPVEEEPSRRRPRAPKEKAQPLEDLAGFTELSETSGHTQESLTAGK 2340
KQR+ K P P A + P A T +G ++S ++ +
Sbjct: 737 TAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEE 796
Query: 2341 ATKIPCESPPLEVVDTTASTKRHLRT---RVQKVQVKEEPSAVKFTQTSGETTDADKEPA 2397
ES E +T A K +T R KE P G+T + +
Sbjct: 797 ------ESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAG 850
Query: 2398 GEDKGIKALKESAKQTPAPAASVTGSRRRPRAPRESAQAIEDLAGFKDPAAGHTEESMTD 2457
+D + +ES APAA SAQ I+ F DP + T
Sbjct: 851 KQDDSGSSSEESDSDGEAPAAVT------------SAQVIKPPLIFVDPNRSPAGPAATP 898
Query: 2458 DKTTKIPCKSSPELEDTATSSKRRPRTRAQKVEV--KEELLAVGKLTQT-SGETTHTDKE 2514
+ S+P + S+ R + ++ +V + L G T + T H
Sbjct: 899 ---AQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIA 955
Query: 2515 PVGEGKGTKAFKQPAK----RKLDAEDVIGSRRQPRAPKEKAQPLEDLASFQELSQTPGH 2570
P G + K+ ++ +K + S++ P + L+ LA +Q P
Sbjct: 956 PKASMAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVA 1015
Query: 2571 TEELANGAADSFTSAPKQTPDSGKPLKISRRVLRAPKVEPVGDVVSTRDPVKSQSKSNTS 2630
+ ++G + + P +P S LR PK+ V +T+ P S ++S
Sbjct: 1016 RTQPSSGVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQ--ATKAPESSDDSEDSS 1073
Query: 2631 LPPLPFKRGGGKDG-SVTGTKRLRCM-PAP---EEIVEELPA--SKKQRVAPR---ARGK 2680
G +DG G K + P P E +VEE A S+ VAP G
Sbjct: 1074 ----DSSSGSEEDGEGPQGAKSAHTLGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGY 1129
Query: 2681 SSEPVVIMKRSLRTSAKRIEPAEELNS----NDMKTNKEEHKLQDSV----PENKG---- 2728
+ + + +++ + ++S D K+E K Q + P+ G
Sbjct: 1130 MTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAA 1189
Query: 2729 ---ISLRSRRQNK---------------------------TEAEQQITEVFVLAERIEIN 2758
+SR+ K EA+ Q + V VL E +E
Sbjct: 1190 SGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQE 1249
Query: 2759 RNEKKPMKTSPEMDIQNPDDGARK-----PIPRDKVTENKRCLRSARQNES--SQPKVAE 2811
R KK + T+ E + + RK P R ++ K+ L + E+ S K +
Sbjct: 1250 R--KKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSPEKTST 1307
Query: 2812 ESGG---QKSAKVLMQNQKGKGEAGNSDSMCLRSRKTKSQPAASTLES------KSVQRV 2862
S G + A ++ +KGKG G+ + + + Q T+E KS +
Sbjct: 1308 TSKGKAKRDKASGDVKEKKGKGSLGSQGAK--DEPEEELQKGMGTVEGGDQSNPKSKKEK 1365
Query: 2863 TRSVKRCAENPKKAEDNVCVKKIRTRSHRDSE 2894
+S KR + KK + KK + S +DSE
Sbjct: 1366 KKSDKRKKDKEKKEKK----KKAKKASTKDSE 1393
>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
Length = 5478
Score = 60.8 bits (146), Expect = 2e-08
Identities = 386/1988 (19%), Positives = 613/1988 (30%), Gaps = 275/1988 (13%)
Query: 657 TPTHTKQQLKASLGKVGVKEELLAVGKFTRTS-GETTHTHREPAGDGKSIR----TFKES 711
T + Q+ AS G E L+ G T +S G+ + T GD ++ T
Sbjct: 3045 TTSGLSQEPTASHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSG 3104
Query: 712 PKQILDPAARVTGMKKWPRTP--------KEEAQSLEDLAGFKELFQTPGPSEESMTDEK 763
+ P TG TP +EE+ + + + +P + + +
Sbjct: 3105 LVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVS 3164
Query: 764 TTKIACKSPPPESVDTPTSTKQWPKRSLRKADVEEE--------FLALRKLTPSAGKAML 815
TT + S P + + +ST RS V F + G+
Sbjct: 3165 TTYHSRPSSTPTTHFSASSTTLG--RSEESTTVHSSPGATGTALFPTRSATSVLVGEPTT 3222
Query: 816 TPKPAGGDEKDIKAFMGTPVQKLDLAGTLPGSKRQLQTPKEKAQALEDLAGFKELFQT-- 873
+P +G E T + + T S R T A +G E T
Sbjct: 3223 SPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTS--SGVSEESTTSH 3280
Query: 874 --PGHTEELVAAGKTTKIPCDSPQSDPVDTPTSTKQRPKRSIRKADVEGELLACRNLMPS 931
PG T G TT + +P ST A G + P
Sbjct: 3281 SRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSGPG 3340
Query: 932 AGKAMHTPKPSVGEEKDIIIFVGTPVQKLDLTENLTGSKRRPQTPKEEAQALEDLTGFKE 991
+ + P + ++ TPV + + T S T + E+ + K+
Sbjct: 3341 STETTLLPDNTTASG---LLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKD 3397
Query: 992 LFQTPGHTEEAVAAGKTTKMPCESSPPE---SADTPTSTRRQPKTPLEKRDVQKELSALK 1048
P T A TT SS P SA + T R + T + V +
Sbjct: 3398 TTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSP 3457
Query: 1049 KLTQTSG---ETTHTDKVPGGEDKSINAFRETAKQKLDPAASVTGSKRHPKTKEKAQPLE 1105
+ TSG E+T PG + + P + T + T +
Sbjct: 3458 ARSTTSGLVEESTTYHSSPG-----------STQTMHFPESDTTSGRGEESTTSHSSTTH 3506
Query: 1106 DLAGLKELFQTPVCTDKPTTHEKTTKIACRSQPDPVDTPTSSKPQSKRSLRKVDVEEEFF 1165
++ T ++PT++ + + T + +S S D
Sbjct: 3507 TISSAPST--TSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIV 3564
Query: 1166 ALRKRTPSAGKAMHTPKPAVSGEKNIYAFMGTPVQKLDLTENLTGSKRRLQTPKEKAQAL 1225
+ T S T P SG A G+ L+E T +P+ A L
Sbjct: 3565 LPARSTTSVLLGESTTSPISSGSMETTALPGSTTTP-GLSEKSTTFH---SSPRSPATTL 3620
Query: 1226 EDLAGFKELFQTRGHTEESMTNDKTAKVACKSSQPDPDKNPASSKRRLKTSLGKVGVKEE 1285
+ + G +EES T+ ++ PD P S R TS G +
Sbjct: 3621 SPAST-----TSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLS-RHSTTSHSSPGSTDT 3674
Query: 1286 LLAVGKLTQTSGETTHTHTEPTGDGKSMKAFMESPKQILDSAASLT------GSKRQLRT 1339
L T TSG + + T + G + A L T GS
Sbjct: 3675 TLLPASTT-TSGSSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLF 3733
Query: 1340 PKGKSEVPEDLAGFIELFQTPSHTKESMTNEKTTKVSYRASQPDLVDTPTSSKPQPKR-- 1397
P + +G +E + S + +TT ++ P L T+ + P
Sbjct: 3734 PDSTTS-----SGIVE---ASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTH 3785
Query: 1398 ------SLRKADTEEEFLAFRKQTPSAGKAMHTPKPAV--GEEKDINTFLGTPVQKLDQP 1449
S A EE R +P + H P + G + F +P D
Sbjct: 3786 TTPSPPSTATAPVEESTTYHR--SPGSTPTTHFPASSTTSGHSEKSTIFHSSP----DAS 3839
Query: 1450 GNLPGSNRRLQTRKEKAQALEELTGFRELFQTP-CTDNPTTDEKTTKKILCKSPQSDPAD 1508
G P S + + ++ G E+ P T P E +T SP+S
Sbjct: 3840 GTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTT--FYSSPRS---- 3893
Query: 1509 TPTNTKQRPKRSLKKADVEEEFLAFRKLTPSAGKAMHTPKAAVGEEKDINTFVGTPVEKL 1568
PT T S+ V EE R P + + +P + T G E
Sbjct: 3894 -PTTTLS--PASMTSLGVGEESTTSRS-QPGSTHSTVSPAST--------TTPGLSEEST 3941
Query: 1569 DLLGNLPGSKRRPQTPKEKAKAL--EDLAGFKEL---FQTPGHTEESMTDDKITEVSCKS 1623
+ + PGS P+ ++ E+ F T TE+S T +TE S
Sbjct: 3942 TVYSSSPGSTETTVFPRSTTTSVRREEPTTFHSRPASTHTTLFTEDSTTSG-LTEESTAF 4000
Query: 1624 PQPDPVKTPTSSKQRLKISLGKVGVKEEVLPVGKLTQTSGKTTQTHRETAGDGKSIKAFK 1683
P +P S++ L +L + EE + ++G R T
Sbjct: 4001 PG-----SPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSG-----LVG 4050
Query: 1684 ESAKQMLDPANYGTGMERWPRTPKEEAQSLEDLAGFKELFQTPDHT------------EE 1731
ES L P++ T P +P + S E F ++PD T EE
Sbjct: 4051 ESTPSRLSPSS--TETTTLPGSPTTPSLS-EKSTTFYTSPRSPDATLSPATTTSSGVSEE 4107
Query: 1732 STTDDKTTKIACKSPPPESMDTPTSTRRRPKTPLGKRDIVEEL--------SALKQLTQT 1783
S+T + P+S T + + P T + E S+L Q + T
Sbjct: 4108 SSTSHSQPGSTHTTAFPDSTTT-SGLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTT 4166
Query: 1784 THTDKVPGDEDKGI---NVFRETAKQKLDPAASVTGSKRQPRTPKGKAQPLEDLAGLKE- 1839
H+ PGD + + + + P S TGS TP GL+E
Sbjct: 4167 FHSS--PGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTS-----TGLQEE 4219
Query: 1840 --LFQT-PICTDKPTTHEKTTKIACR---SPQPDPVGTPTIFKPQSKRSLRKADVEEESL 1893
FQ+ P +D + TT + + P TPT S +L ++ EES
Sbjct: 4220 STTFQSWPSSSDTTPSPPSTTAVPVEVSTTYHSRPSSTPTTHFSASSTTLGRS---EEST 4276
Query: 1894 ALRKRTPSVGKAMDTPKPAGG---DEKDMKAFMGTPVQKLDLPGNLP------------G 1938
+ + G A+ + A E + LPG+
Sbjct: 4277 TVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYS 4336
Query: 1939 SKRWPQTPKEKAQALEDLAGFKELFQT----PG----------TDKPTTDEKTTKIACKS 1984
S R P T A +G E T PG T P +++T
Sbjct: 4337 SPRSPDTTLSPASTTS--SGVSEESTTSHSRPGSMHTTAFPSSTTMPGVSQESTASHSSP 4394
Query: 1985 PQPD----PVDTPASTKQRPKRNLRKADVEEEFLALRKRTPSAGKAMDTPKPAVSDEKNI 2040
D P T AS+ + E L T ++G ++ P S +
Sbjct: 4395 GSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASG-LLEASTPVHSSTGSP 4453
Query: 2041 NTFVE-----TPVQKLDLLGNLPGSKRQPQTPKEKAEALEDL-------------VGFKE 2082
+T + T + + P SK P A +L F
Sbjct: 4454 HTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSA 4513
Query: 2083 LFQTPGHTEESMTDDKITEVSCKSPQPESFKTSRSSKQRLKIPLVKVDMKEEPLAVSKLT 2142
T G +EES T + +P P TS ++ + S T
Sbjct: 4514 SSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPESNTT 4573
Query: 2143 RTSGE------TTQTHTEPTGDSKSIKAFKESPKQILDPAASVTGSRRQLRT---RKEKA 2193
GE ++ THT + S + +E P ++ T T R E++
Sbjct: 4574 SGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEES 4633
Query: 2194 RALEDLVDFKELFSAPGHTEESMTIDKNTKIPCKS------------PPPELTDTATSTK 2241
A D P + S+ + ++T P S P L++ +T+
Sbjct: 4634 TASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFH 4693
Query: 2242 RCPKTRPRKEVKEELSAVERLTQTSGQSTHTHKEPASGDEGIKVLKQRAKKKPNPVEEEP 2301
P + P + + R S +ST H P + P+P
Sbjct: 4694 SSPSSTPTTHFSASSTTLGR----SEESTTVHSSPVA-----------TATTPSPARSTT 4738
Query: 2302 SRRRPRAPKEKAQP-LEDLAGFTELSETSGHTQESLTAGKATKIPCESPPLEVVDTTAST 2360
S + + P F E S SG ++ES T+ +T SPP
Sbjct: 4739 SGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPP-STTSALVEE 4797
Query: 2361 KRHLRTRVQKVQVKEEPSAVKFTQTSGETTDADKEPAGEDKGIKAL----------KESA 2410
+ + P + + S E+T + P + GI L ES
Sbjct: 4798 PTSYHSSPGSIATTHFPESSTTSGRSEESTASHSSP--DTNGITPLPAHFTTSGRIAEST 4855
Query: 2411 KQTPAPAASVTGSRRRPRAPRESAQAIEDLAGFKDPAAGHTEESMTDDKTTKIPCKSSPE 2470
+P + T P SA++ + + P + SMT + P +
Sbjct: 4856 TFYISPGSMETTLASTATTPGLSAKSTILYSSSRSPDQTLSPASMTSSSISGEPTSLYSQ 4915
Query: 2471 LEDTATSS 2478
E T T++
Sbjct: 4916 AESTHTTA 4923
Score = 59.7 bits (143), Expect = 4e-08
Identities = 378/1883 (20%), Positives = 595/1883 (31%), Gaps = 222/1883 (11%)
Query: 657 TPTHTKQQLKASLGKVGVKEELLAVGKFTRTS--GETTHTHREPAGDGKSIRTFKESPKQ 714
T + Q+ S G + L+ G T S E+T H P ++ +
Sbjct: 2599 TTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSG 2658
Query: 715 ILDPAARVTGMKKWPRTPKEEAQSLED-LAGFKELFQTPGPSEESMTDEKTTKIACKSPP 773
I++ + RV PRT A S L G FQT S + +T A
Sbjct: 2659 IVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTTFQTHPASTHTTPSPPSTATAPVEES 2718
Query: 774 PESVDTP--TSTKQWPKRSLRKADVEEEFLALRK-----LTPSAGKAMLTPKPAGGDEKD 826
+P T T +P S E+ + TPS+ + + + G+
Sbjct: 2719 TTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGR---GESTT 2775
Query: 827 IKAFMG-TPVQKLDLAGTLPGSKRQLQT----PKEKAQALEDLA----GFKELFQT---- 873
+ G T + L + T PG T P+ L + G E T
Sbjct: 2776 SRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQ 2835
Query: 874 PGHTEELVAAGKTTKIPCDSPQSDPV--DTPTSTKQRPKRSIRKADVEGELLACRNLMPS 931
PG T V+ TT P S +S V +P ST+ V GE + P+
Sbjct: 2836 PGSTHSTVSPASTTT-PGLSEESTTVYSSSPGSTETTVFPRSTTTSVRGEEPTTFHSRPA 2894
Query: 932 AGKAMHTPKPSV--GEEKDIIIFVGTPVQ-KLDLTENLTGSKRRPQTPKEEAQALEDLTG 988
+ + S G ++ F G+P + L LT + EE+ +G
Sbjct: 2895 STHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLG-----EESTTFPSSSG 2949
Query: 989 FKELFQTPGHTEEAVAAGK------------TTKMPCESSPPESADTPTSTRRQPKTP-- 1034
+P + + G+ TT +P + P ++ T+ P++P
Sbjct: 2950 STGTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDA 3009
Query: 1035 ------LEKRDVQKELS------------ALKKLTQTSG---ETTHTDKVPGGEDKSINA 1073
V +E S A T TSG E T + G + +++
Sbjct: 3010 TLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTASHSSQGSTEATLSP 3069
Query: 1074 FRETAKQKLDPAASVTGSKRHPKTK------------EKAQPLEDLAGLKELFQTPVCTD 1121
TA + + S +T E + P G TP +
Sbjct: 3070 GSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASST 3129
Query: 1122 KPTTHEKTTKIACRSQPDPVDTPTSSKPQSKRSLRKVDVEEEFFALRKRTPSAGKAMHTP 1181
E++T +S P DT T S P + + V+V + + TP+ + +
Sbjct: 3130 SAGLQEESTTF--QSWPSSSDT-TPSPPGTTAA--PVEVSTTYHSRPSSTPTTHFSASST 3184
Query: 1182 KPAVSGEKN-IYAFMGTPVQKLDLTENLTGSKRRLQTPKEKAQALEDLAGFKELFQTRGH 1240
S E +++ G L T + T T + +G E G
Sbjct: 3185 TLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPIS------SGSTETTALPGS 3238
Query: 1241 TEESMTNDKTAKVACKSSQPDPDKNPASS-----KRRLKTSLGKVGVKEELLAVGKLTQ- 1294
T + ++K+ PD +PAS+ TS + G G T
Sbjct: 3239 TTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMP 3298
Query: 1295 -TSGETTHTHTEPTGDGKSMKAFMESPKQILDSAASLTGSKRQLRTPKGKSE---VPEDL 1350
S E+T +H+ P ++ SP +A+SL + G +E +P++
Sbjct: 3299 GVSQESTASHSSPGSTDTTL-----SPGST--TASSLGPESTTFHSGPGSTETTLLPDNT 3351
Query: 1351 --AGFIELFQTPSHTKESMTNEKTTKVSYRASQPDLVDTPTSSKPQPKRSLRKADTEEEF 1408
+G +E TP H S T T +S S ++ T + A
Sbjct: 3352 TASGLLEA-STPVH---SSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTS 3407
Query: 1409 LAFRKQTPSAGKAMHTP-------KPAVGEEKDINTFLGTPVQKLDQPGNLPGSNRRLQT 1461
T S G TP +G ++ T +PV P + L
Sbjct: 3408 AFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLV- 3466
Query: 1462 RKEKAQALEELTGFRELFQTPCTDNP-------TTDEKTTKKILCKSPQSDPA--DTPTN 1512
E++ G + P +D TT +T + +P + A + PT+
Sbjct: 3467 --EESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTS 3524
Query: 1513 TKQRPKR--------SLKKADVEEEFLAFRKLTPSAGK----AMHTPKAAVGEEKDINTF 1560
P S + EE A + G A T +GE
Sbjct: 3525 YHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPIS 3584
Query: 1561 VGTPVEKLDLLGNL--PGSKRRPQT----PKEKAKALEDLAGFKELFQTPGHTEESMTDD 1614
G+ +E L G+ PG + T P+ A L + + G +EES T
Sbjct: 3585 SGS-METTALPGSTTTPGLSEKSTTFHSSPRSPATTLSPAST-----TSSGVSEESTTSH 3638
Query: 1615 KITEVSCKSPQPDPVKTPTSSKQRLKISLGKVGVKEEVLPVGKLTQTSGKTTQTHRETAG 1674
+ + PD TP S+ +LP T TSG + ++ +
Sbjct: 3639 SRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPAS--TTTSGSSQESTTSHSS 3696
Query: 1675 DGKSIKAFKESAKQMLDPANYGTGMERWPRTPKEEAQSL-EDLAGFKELFQTPDHTEEST 1733
G + A + L ++G + +P +L D + + ST
Sbjct: 3697 SGSTDTALSPGSTTAL---SFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSST 3753
Query: 1734 TDDKTTKIACKSPPP----ES---MDTPTSTRRRPKTPLGKRDIVEELSALKQLTQTTHT 1786
+TT S P ES P ST P P VEE + + +T T
Sbjct: 3754 GSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPT 3813
Query: 1787 DKVPGDEDKGINVFRETAKQKLDPAASVTGSKRQPRTP-KGKAQPLEDLAGLKELFQTPI 1845
P + + T A+ T S T +G++ G E+ P
Sbjct: 3814 THFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPG 3873
Query: 1846 CTDKPTTHEKTTKIACRSPQPDPVGTPTIFKPQSKRSLRKADVEEESLALRKRTPSVGKA 1905
T P E +T P T P S SL V EES R + G
Sbjct: 3874 STTTPGLSEASTTF-----YSSPRSPTTTLSPASMTSL---GVGEESTTSRSQP---GST 3922
Query: 1906 MDTPKPAGGDEKDMKAFMGTPVQKLDLPGNLPGSKRWPQTPKEKAQAL--EDLAGFKELF 1963
T PA G + + + PGS P+ ++ E+ F
Sbjct: 3923 HSTVSPAS------TTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRREEPTTFHSRP 3976
Query: 1964 QTPGTDKPTTDEKTTKIACKSPQPDPVDTPASTKQRPKRNLRKADVEEEFLALRKRTPSA 2023
+ T T D T+ + +S +PAST+ L AD+ EE + S
Sbjct: 3977 ASTHTTLFTEDSTTSGLTEESTAFP--GSPASTQTGLPATLTTADLGEESTTFPSSSGST 4034
Query: 2024 GKAMDTPKPAVSDEKNINTFVETPVQKLDLLGNLPGSKRQPQTPKEKAEALEDLVGFKEL 2083
G + + S +T + LPGS P EK+ +
Sbjct: 4035 GTKLSPARSTTSGLVGESTPSRLSPSSTETT-TLPGSPTTPSL-SEKSTTFYTSPRSPDA 4092
Query: 2084 FQTPGHTEESMTDDKITEVSCKSPQPESFKTSRSSKQRLKIPLVKVDMKEEPLAVSKLTR 2143
+P T S + E S QP S T+ + +EP S ++
Sbjct: 4093 TLSPATTTSSGVSE---ESSTSHSQPGSTHTTAFPDS-----TTTSGLSQEP-TTSHSSQ 4143
Query: 2144 TSGETTQTHTEPTGDS--KSIKAFKESP---KQILDPAASVTGSRRQLRTRKEKARALED 2198
S E T + T S + F SP + L P ++T + T +
Sbjct: 4144 GSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLH 4203
Query: 2199 LVDFKELFSAPGHTEESMTIDKNTKIPCKSP-PPELTDTATSTKRCPKTRPRKEVKEELS 2257
++ G EES T +P PP T +RP S
Sbjct: 4204 TTLTPASSTSTGLQEESTTFQSWPSSSDTTPSPPSTTAVPVEVSTTYHSRPSSTPTTHFS 4263
Query: 2258 AVERLTQTSGQSTHTHKEPASGDEGIKVLKQRAKKKPNPVEEEPSRRRPRAPKEKAQPLE 2317
A S +ST H P G G + R+ + + EP+ + + L
Sbjct: 4264 ASSTTLGRSEESTTVHSSP--GATGTALFPTRS--ATSVLVGEPTTSPISSGSTETTALP 4319
Query: 2318 DLAGFTELSETSGHTQESLTAGKATKIPCESPPLEVVDTTASTKRHLRTRVQKVQVKEEP 2377
LSE S S + T P + V + ST H +R + P
Sbjct: 4320 GSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGV--SEESTTSH--SRPGSMHTTAFP 4375
Query: 2378 SAVKFTQTSGETTDADKEPAGED 2400
S+ S E+T + P D
Sbjct: 4376 SSTTMPGVSQESTASHSSPGSTD 4398
Score = 52.4 bits (124), Expect = 7e-06
Identities = 439/2191 (20%), Positives = 670/2191 (30%), Gaps = 312/2191 (14%)
Query: 623 QNLLQTQDHAKAPKSEKGKITKMPCQSLQPEPINTPTHTKQQLKASLGKVGVKEELLAVG 682
Q+ ++D + AP K+ + P +TPT +LG
Sbjct: 422 QSWPSSKDTSPAPSGTTSAFVKLST-TYHSSPSSTPTTHFSASSTTLGH----------- 469
Query: 683 KFTRTSGETTHTHREPAGDGKSIRTFKESPKQILDPAARVTGMKKWPRTPKEEAQSLEDL 742
S E+T H P + T P PA T T +
Sbjct: 470 -----SEESTPVHSSP------VATATTPP-----PARSATSGHVEESTAYHRSPGSTQT 513
Query: 743 AGFKELFQTPGPSEESMTDEKTTKIACKSPPPESVDTPTSTKQWPKRSLRKADVEEEFLA 802
F E T G SEES T +T S TP++T S + E
Sbjct: 514 MHFPESSTTSGHSEESATFHGSTTHTKSS-------TPSTTAALAHTSYHSSLGSTETTH 566
Query: 803 LRKLTPSAGKAMLTPKPAGGDEKDIKAFMGTPVQKLDLAGTLPGSKRQLQTPKEKAQALE 862
R + +G++ A D A P AG+ P TP +
Sbjct: 567 FRDSSTISGRS--EESKASHSSPDAMATTVLP------AGSTPSVLVGDSTPSPISSGSM 618
Query: 863 DLAGFKELFQTPGHTEELVA------AGKTTKIPCDSPQSDPVDTPTSTKQRPKRSIRKA 916
+ PG +E+ + TT +P S + T++ RP + A
Sbjct: 619 ETTALPGSTTKPGLSEKSTTFYSSPRSPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTA 678
Query: 917 DVEGELLACRNLMPSAGKAMHTPKPSVGEEKDIIIFVGTPVQKLDLTENLTGSKRRPQTP 976
MP + S G + T L E T R T
Sbjct: 679 ------FPGSTTMPGLSQESTASHSSPGPTDTTLSPGSTTASSLG-PEYTTFHSRPGST- 730
Query: 977 KEEAQALEDLTGFKELFQTPGHTEEAVAAGKTTKMPCESSPPESADT-----PTSTRRQP 1031
E L D T L + + + TT P S+ + T P+S +P
Sbjct: 731 --ETTLLPDNTTASGLLEASMPVHSSTRSPHTTLSPAGSTTRQGESTTFHSWPSSKDTRP 788
Query: 1032 KTPLEKRDVQKELSALKKLTQTSGETTHTD--KVPGG---EDKSINAFRETAKQKLDPAA 1086
P E S + +S TTH G E + ++ + + P +
Sbjct: 789 APPTTT-SAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPES 847
Query: 1087 SVTGSKRHPKTKEKAQPLEDLAGLKELFQTPVCTDKPTTHEKTTKIACRSQPDPVDTPTS 1146
T + T + ++ T ++PT++ + + T +
Sbjct: 848 DTTSGRGEESTTSHSSTTHTISSAPST--TSALVEEPTSYHSSPGSTATTHFPDSSTTSG 905
Query: 1147 SKPQSKRSLRKVDVEEEFFALRKRTPSAGKAMHTPKPAVSGEKNIYAFMGTPVQKLDLTE 1206
+S S D + T S T P SG A G+ L+E
Sbjct: 906 RSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTP-GLSE 964
Query: 1207 NLTGSKRRLQTPKEKAQALEDLAGFKELFQTRGHTEESMTNDKTAKVACKSSQPDPDKNP 1266
T +P+ A L + + G +EES T+ ++ PD P
Sbjct: 965 RSTTFH---SSPRSPATTLSPAST-----TSSGVSEESTTSRSRPGSTHTTAFPDSTTTP 1016
Query: 1267 ASSKRRLKTSLGKVGVKEELLAVGKLTQTSGETTHTHTEPTGDGKSMKAFMESPKQILDS 1326
S R TS G + L T TSG + + T + G + A L
Sbjct: 1017 GLS-RHSTTSHSSPGSTDTTLLPASTT-TSGPSQESTTSHSSSGSTDTALSPGSTTALSF 1074
Query: 1327 AASLT------GSKRQLRTPKGKSEVPEDLAGFIELFQTPSHTKESMTNEKTTKVSYRAS 1380
T GS P + +G +E + S + +TT ++
Sbjct: 1075 GQESTTFHSNPGSTHTTLFPDSTTS-----SGIVE---ASTRVHSSTGSPRTTLSPASST 1126
Query: 1381 QPDLVDTPTSSKPQPKR--------SLRKADTEEEFLAFRKQTPSAGKAMHTPKPAV--G 1430
P L T+ + P S A EE R +P + H P + G
Sbjct: 1127 SPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHR--SPGSTPTTHFPASSTTSG 1184
Query: 1431 EEKDINTFLGTPVQKLDQPGNLPGSNRRLQTRKEKAQALEELTGFRELFQTP-CTDNPTT 1489
+ F +P D G P S + + ++ G E+ P T P
Sbjct: 1185 HSEKSTIFHSSP----DASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGL 1240
Query: 1490 DEKTTKKILCKSPQSDPADTPTNTKQRPKRSLKKADVEEEFLAFRKLTPSAGKAMHTPKA 1549
E +T SP+S PT T S+ V EE R P + + +P +
Sbjct: 1241 SEASTT--FYSSPRS-----PTTTLS--PASMTSLGVGEESTTSRS-QPGSTHSTVSPAS 1290
Query: 1550 AVGEEKDINTFVGTPVEKLDLLGNLPGSKRRPQTPKEKAKAL--EDLAGFKEL---FQTP 1604
T G E + + GS P ++ E+ F T
Sbjct: 1291 T--------TTPGLSEESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHSRPASTHTT 1342
Query: 1605 GHTEESMTDDKITEVSCKSPQPDPVKTPTSSKQRLKISLGKVGVKEEVLPVGKLTQTSGK 1664
TE+S T +TE S P +P S++ L +L + EE + ++G
Sbjct: 1343 LFTEDSTTSG-LTEESTAFPG-----SPASTQTGLPATLTTADLGEESTTFPSSSGSTGT 1396
Query: 1665 TTQTHRETAGDGKSIKAFKESAKQMLDPANYGTGMERWPRTPKEEAQSLEDLAGFKELFQ 1724
R T ES L P++ T P +P + S E F +
Sbjct: 1397 KLSPARSTTSG-----LVGESTPSRLSPSS--TETTTLPGSPTTPSLS-EKSTTFYTSPR 1448
Query: 1725 TPDHT------------EESTTDDKTTKIACKSPPPESMDTPTSTRRRPKTPLGKRDIVE 1772
+PD T EES+T + P+S T + + P T + E
Sbjct: 1449 SPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTT-SDLSQEPTTSHSSQGSTE 1507
Query: 1773 EL--------SALKQLTQTTHTDKVPGDEDKGI---NVFRETAKQKLDPAASVTGSKRQP 1821
S+L Q + T H+ PGD + + + + P S TGS
Sbjct: 1508 ATLSPGSTTASSLGQQSTTFHSS--PGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTT 1565
Query: 1822 RTPKGKAQPLEDLAGLKE---LFQT-PICTDKPTTHEKTTKIACR---SPQPDPVGTPTI 1874
TP AGL+E FQ+ P +D + TT + P TPT
Sbjct: 1566 LTPASSTS-----AGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTT 1620
Query: 1875 FKPQSKRSLRKADVEEESLALRKRTPSVGKAMDTPKPAGGDEKDMKAFMGTPVQKLDLPG 1934
S +L ++ EES + + G A+ + A +G P
Sbjct: 1621 HFSASSTTLGRS---EESTTVHSSPGATGTALFPTRSA------TSVLVGEPTTS----- 1666
Query: 1935 NLPGSKRWPQTPKEKAQALEDLAGFKELFQTPG-TDKPTTDEKTTKIACKSPQPDPVDTP 1993
P S +G E PG T EK+T PD +P
Sbjct: 1667 --PIS-----------------SGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSP 1707
Query: 1994 ASTKQRPKRNLRKADVEEEFLALRKRTPSAGKAM---DTPKPAVSDEKNINTFVETPVQK 2050
AST + V EE R S T P VS E +
Sbjct: 1708 ASTTS--------SGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDT 1759
Query: 2051 LDLLGNLPGSKRQPQTP-------KEKAEALEDLVGFKELFQ--TPGHTEESMTDDKITE 2101
G+ S P++ + L D L + TP H+ ++
Sbjct: 1760 TLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSP 1819
Query: 2102 VSCKSPQPES--FKTSRSSKQRLKIPLVKVDMKEEPLAVSKLTRTSGETTQTHTEPT--G 2157
+ Q ES F++ SSK + P E S + +S TT T G
Sbjct: 1820 AGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLG 1879
Query: 2158 DSKSIKAFKESPKQIL---DPAASVTGSRRQLRTRKEKARALEDLVDFKELFSAPGHTEE 2214
S+ SP PA S T + T + + F E +A G +EE
Sbjct: 1880 RSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEE 1939
Query: 2215 SMTIDKNTKIPCKSPP---PELTDTATSTKRCPKTRPRKEVKEELSAVERLTQTSGQSTH 2271
S T +T SPP L + TS P + + + TSG+S
Sbjct: 1940 SRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSTATTHFPDS-------STTSGRSEE 1992
Query: 2272 THKEPASGD-EGIKVLKQRAKKKPNPVEEEPSRRRPRAPKEKAQPLEDLAGFTELSETSG 2330
+ +S D G VL R+ E S + + A P G T T G
Sbjct: 1993 STASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALP-----GST---TTPG 2044
Query: 2331 HTQESLTAGKATKIPCESPPLEVVDTTA------STKRHLRTRVQKVQVKEEPSAVKFTQ 2384
+++S T + + P + L TT+ ST H +R P +
Sbjct: 2045 LSEKSTTFHSSPRSPATT--LSPASTTSSGVSEESTTSH--SRPGSTHTTAFPDSTTTPG 2100
Query: 2385 TSGETTDADKEPAGEDKGIKALKESAKQTPAPAASVTGSRRRPRAPRE-----SAQAI-- 2437
S +T + P D L ++ T P+ T S P + S A+
Sbjct: 2101 LSRHSTTSHSSPGSTD---TTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSF 2157
Query: 2438 --EDLAGFKDPAAGHTEESMTDDKTTKIPCKSSPELEDTATSSKRRPRTRAQKVEVKEEL 2495
E P + HT ++ D TT + ++T S R T + L
Sbjct: 2158 GQESTTFHSSPGSTHT--TLFPDSTTSSGIVEASTRVHSSTGSPR--TTLSPASSTSPGL 2213
Query: 2496 LAVGKLTQTSGETTHTDKEPVGEGKGTKAFKQPAKRKLDAEDVIGSRRQPRAPKEKAQPL 2555
QT +THT P P+ E+ R P + P
Sbjct: 2214 QGESTAFQTHPASTHTTPSP------------PSTATAPVEESTTYHRSPGSTPTTHFPA 2261
Query: 2556 EDLASFQELSQTPGHTEELANG----AADSFTSAPKQTPDSG-KPLKISRRVLRAPKVEP 2610
S T H+ A+G +A S TS ++ S P L P
Sbjct: 2262 SSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTP 2321
Query: 2611 VGDVVSTRDPVKSQSKSNTSLPPLPFKRGGGKDGSVTGTKRLRCMPAPEEIVEELPASKK 2670
ST +S + T P G G++ + + ++ P +
Sbjct: 2322 GLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSE 2381
Query: 2671 QRVAPRARGKSSEPVVIMKRSLRTSAKRIEP 2701
+ + S + R+ TS + EP
Sbjct: 2382 ESTTVYSSSPGSTETTVFPRTPTTSVRGEEP 2412
Score = 48.5 bits (114), Expect = 9e-05
Identities = 317/1608 (19%), Positives = 504/1608 (31%), Gaps = 226/1608 (14%)
Query: 985 DLTGFKELFQTPGHTEEAVAAGKTTKMPCESSPP----ESA---DTPTSTRRQPKTPLEK 1037
D T + + + + +TT P S+ P ES P ST P P
Sbjct: 1095 DSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTA 1154
Query: 1038 RDVQKELSALKKLTQTSGETTHTDKVPGGEDKSINAFRETAKQKLDPAASVTGSKRHPKT 1097
+E + + S +T T P S ++ + T A+ T S H T
Sbjct: 1155 TAPVEESTTYHR----SPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTT 1210
Query: 1098 KEKAQPLEDLA--GLKELFQTPVCTDKPTTHEKTTKIACRSQPDPVDTPTSSKPQSKRSL 1155
+ + G E+ P T P E +T P T+ P S SL
Sbjct: 1211 SGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTF----YSSPRSPTTTLSPASMTSL 1266
Query: 1156 RKVDVEEEFFALRKR---TPSAGKAMHTPKPAVSGEKN-IYAFMGTPVQKLDLTENLTGS 1211
V EE R + T S T P +S E +Y+ + + T S
Sbjct: 1267 ---GVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSRGSTETTVFPHSTTTS 1323
Query: 1212 KRRLQ-TPKEKAQALEDLAGFKELFQTRGHTEESMTNDKTAKVACKSSQPDPDKNPASSK 1270
+ T A F E T G TEES ++ P +PAS++
Sbjct: 1324 VHGEEPTTFHSRPASTHTTLFTEDSTTSGLTEES------------TAFPG---SPASTQ 1368
Query: 1271 RRLKTSLGKVGVKEELLAVGKLTQTSGETTHTHTEPTGDGKSMKAFMESPKQILDSAASL 1330
L +L + EE +S +T T P S +P ++ S+
Sbjct: 1369 TGLPATLTTADLGEESTTF----PSSSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTET 1424
Query: 1331 TGSKRQLRTPKGKSEVPEDLAGFIELFQTPSHT------------KESMTNEKTTKVSYR 1378
T TP + E F ++P T +ES T+ ++
Sbjct: 1425 TTLPGSPTTPS----LSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHT 1480
Query: 1379 ASQPDLVDTPTSSKPQPKRSLRKADTEEEFLAFRKQTPSAGKAMHTPKPAVGEEKDI--- 1435
+ PD T S+ + TE S G+ T + G+ +
Sbjct: 1481 TAFPDSTTTSDLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLP 1540
Query: 1436 -NTFLGTPVQKLDQPGNLPGSNRRLQTRKEKAQA--LEELTGFRELFQTPCTDNPTTDEK 1492
+T V+ + GS T A EE T F+ + + P+
Sbjct: 1541 DDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQS-WPSSSDTTPSPPGT 1599
Query: 1493 TTKKI-LCKSPQSDPADTPTNTKQRPKRSLKKADVEEEFLAFRKLTPSAGKAMHTPKAAV 1551
T + + + S P+ TPT +L ++ EE + G A+ ++A
Sbjct: 1600 TAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRS---EESTTVHSSPGATGTALFPTRSAT 1656
Query: 1552 GEEKDINTFVGTPVEKLDLLGN-----LPGSKRRPQTPKEKAKALEDLAGFKELFQTPGH 1606
+ VG P G+ LPGS EK+ + +P
Sbjct: 1657 ------SVLVGEPTTSPISSGSTETTALPGSTTTAGL-SEKSTTFYSSPRSPDTTLSPAS 1709
Query: 1607 TEESMTDDKITEVSCKSPQPDPVKTPTSS-----KQRLKISLGKVGVKEEVLPVGKLTQT 1661
T S ++ T + P S+ Q S G + L G T +
Sbjct: 1710 TTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTAS 1769
Query: 1662 S--GKTTQTHRETAGDGKSIKAFKESAKQMLD---PANYGTGMERWPRTP------KEEA 1710
S ++T H ++ +A +L+ P + TG +P + E+
Sbjct: 1770 SLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGES 1829
Query: 1711 QSLEDLAGFKELFQTPDHTEESTTDDKTTKIACKSPPPESMDTPTSTRRRPKTPLGKRDI 1770
+ + K+ P T + + TT S TPT+ T LG+
Sbjct: 1830 TTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGSPS------STPTTHFSASSTTLGRS-- 1881
Query: 1771 VEELSALKQLTQTTHTDKVPGDEDKGINVFRETAKQKLDPAASVTGSKRQPRTPKGKAQP 1830
EE + + T T P V TA P ++ T + T G+++
Sbjct: 1882 -EESTTVHSSPVATATTPSPARSTTSGLVEESTAYHS-SPGSTQTMHFPESSTASGRSEE 1939
Query: 1831 LEDL-AGLKELFQTPICT-----DKPTTHEKTTKIACRSPQPDPVGTPTIFKPQSKRSLR 1884
+ +P T ++PT++ + + PD T + +S S
Sbjct: 1940 SRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSTATTHFPDS-STTSGRSEESTASHS 1998
Query: 1885 KADVEEESLALRKRTPSVGKAMDTPKPAGGDEKDMKAFMGTPVQKLDLPGNLPGSKRWPQ 1944
D + + T SV T P + A G+ PG S +
Sbjct: 1999 SQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTT----PGLSEKSTTFHS 2054
Query: 1945 TPKEKAQALEDLAGFKELFQTPGTDKPTTDEKTTKIACKSPQPDPVDTPASTKQRPKRNL 2004
+P+ A L + + +++ TT + PD TP ++ +
Sbjct: 2055 SPRSPATTLSPAS----TTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHS 2110
Query: 2005 RKADVEEEFLALRKRT--PSAGKAMDTPKPAVSDEKNI--NTFVETPVQKLDLLGNLPGS 2060
+ L T PS P +D +T + Q+ + PGS
Sbjct: 2111 SPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGS 2170
Query: 2061 KRQPQTPKEKAEALEDLVGFKELFQTPGHTEESMTDDKITEVSCKSP----QPESFKTSR 2116
P + G E T H+ ++ S SP + +F+T
Sbjct: 2171 THTTLFPDSTTSS-----GIVEA-STRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHP 2224
Query: 2117 SSKQRLKIPLVKVDMKEEPLAVSKLTRTSGETTQTH----TEPTGDSKSIKAFKESPKQ- 2171
+S P E R+ G T TH + +G S+ F SP
Sbjct: 2225 ASTHTTPSPPSTATAPVEESTTYH--RSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDAS 2282
Query: 2172 --ILDPAASVTGSRRQLRTRKEKARALEDLVDFKELFSAPGHTEESMTIDKNTKIPCKSP 2229
A S T R + T + +PG TE T +P +
Sbjct: 2283 GTTPSSAHSTTSGRGESTTSR----------------ISPGSTEI-------TTLPGSTT 2319
Query: 2230 PPELTDTAT---STKRCPKTRPRKEVKEELSAVERLTQTSGQ--STHTHKEPAS------ 2278
P L++ +T S+ R P T L E T + Q STH+ PAS
Sbjct: 2320 TPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGL 2379
Query: 2279 GDEGIKVLKQRAKKKPNPVEEEPSRRRPRAPKEKAQPLE--------DLAGFTELSETSG 2330
+E V P E R P +P FTE S TSG
Sbjct: 2380 SEESTTVYSS----SPGSTETTVFPRTPTTSVRGEEPTTFHSRPASTHTTLFTEDSTTSG 2435
Query: 2331 HTQESLTAGKATKIPCESPPLEVVDTTASTKRHLRTRVQKVQVKEEPSAVKFTQTSGETT 2390
T+ES T P + AST+ L + + EE + F +SG T
Sbjct: 2436 LTEES------TAFP---------GSPASTQTGLPATLTTADLGEE--STTFPSSSGSTG 2478
Query: 2391 DADKEPAGEDKGIKALKESAKQTPAPAASVT--GSRRRPRAPRESAQAIED-------LA 2441
G+ ++ +P+ + T GS P +S L+
Sbjct: 2479 TTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLS 2538
Query: 2442 GFKDPAAGHTEESMTDDK------TTKIP-CKSSPELEDTATSSKRRP 2482
++G +EES T TT P ++P L +T+S P
Sbjct: 2539 PATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTPGLSRHSTTSHSSP 2586
Score = 48.1 bits (113), Expect = 1e-04
Identities = 279/1445 (19%), Positives = 462/1445 (31%), Gaps = 181/1445 (12%)
Query: 985 DLTGFKELFQTPGHTEEAVAAGKTTKMPCESSPP----ESA---DTPTSTRRQPKTPLEK 1037
D T + + + + +TT P S+ P ES P ST P P
Sbjct: 3735 DSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTA 3794
Query: 1038 RDVQKELSALKKLTQTSGETTHTDKVPGGEDKSINAFRETAKQKLDPAASVTGSKRHPKT 1097
+E + + S +T T P S ++ + T A+ T S H T
Sbjct: 3795 TAPVEESTTYHR----SPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTT 3850
Query: 1098 KEKAQPLEDLA--GLKELFQTPVCTDKPTTHEKTTKIACRSQPDPVDTPTSSKPQSKRSL 1155
+ + G E+ P T P E +T P T+ P S SL
Sbjct: 3851 SGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTF----YSSPRSPTTTLSPASMTSL 3906
Query: 1156 RKVDVEEEFFALRKR---TPSAGKAMHTPKPAVSGEKN-IYAFMGTPVQKLDLTENLTGS 1211
V EE R + T S T P +S E +Y+ + + T S
Sbjct: 3907 ---GVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRSTTTS 3963
Query: 1212 KRRLQ-TPKEKAQALEDLAGFKELFQTRGHTEESMTNDKTAKVACKSSQPDPDKNPASSK 1270
RR + T A F E T G TEES ++ P +PAS++
Sbjct: 3964 VRREEPTTFHSRPASTHTTLFTEDSTTSGLTEES------------TAFPG---SPASTQ 4008
Query: 1271 RRLKTSLGKVGVKEELLAVGKLTQTSGETTHTHTEPTGDGKSMKAFMESPKQILDSAASL 1330
L +L + EE +S +T T P S +P ++ S+
Sbjct: 4009 TGLPATLTTADLGEESTTF----PSSSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTET 4064
Query: 1331 TGSKRQLRTPKGKSEVPEDLAGFIELFQTPSHT------------KESMTNEKTTKVSYR 1378
T TP + E F ++P T +ES T+ ++
Sbjct: 4065 TTLPGSPTTPS----LSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHT 4120
Query: 1379 ASQPDLVDTPTSSKPQPKRSLRKADTEEEFLAFRKQTPSAGKAMHTPKPAVGEEKDI--- 1435
+ PD T S+ + TE S G+ T + G+ +
Sbjct: 4121 TAFPDSTTTSGLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLP 4180
Query: 1436 -NTFLGTPVQKLDQPGNLPGSNRRLQTRKEKAQALEELTGFRE---LFQT-PCTDNPTTD 1490
+T V+ + GS L T A + TG +E FQ+ P + + T
Sbjct: 4181 DDTITSGLVEASTPTHSSTGS---LHTTLTPASSTS--TGLQEESTTFQSWPSSSDTTPS 4235
Query: 1491 EKTTKKI---LCKSPQSDPADTPTNTKQRPKRSLKKADVEEEFLAFRKLTPSAGKAMHTP 1547
+T + + + S P+ TPT +L ++ EE + G A+
Sbjct: 4236 PPSTTAVPVEVSTTYHSRPSSTPTTHFSASSTTLGRS---EESTTVHSSPGATGTALFPT 4292
Query: 1548 KAAVGEEKDINTFVGTPVEKLDLLGN-----LPGSKRRPQTPKEKAKALEDLAGFKELFQ 1602
++A + VG P G+ LPGS EK+ +
Sbjct: 4293 RSAT------SVLVGEPTTSPISSGSTETTALPGSTTTAGL-SEKSTTFYSSPRSPDTTL 4345
Query: 1603 TPGHTEESMTDDKITEVSCKSPQPDPVKTPTSS-----KQRLKISLGKVGVKEEVLPVGK 1657
+P T S ++ T + P+S+ Q S G + L G
Sbjct: 4346 SPASTTSSGVSEESTTSHSRPGSMHTTAFPSSTTMPGVSQESTASHSSPGSTDTTLSPGS 4405
Query: 1658 LTQTS--GKTTQTHRETAGDGKSIKAFKESAKQMLD---PANYGTGMERWPRTP------ 1706
T +S ++T H ++ +A +L+ P + TG +P
Sbjct: 4406 TTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTR 4465
Query: 1707 KEEAQSLEDLAGFKELFQTPDHTEESTTDDKTTKIACKSPPPESMDTPTSTRRRPKTPLG 1766
+ E+ + + K+ P T + + TT S TPT+ T LG
Sbjct: 4466 QGESTTFQSWPNSKDTTPAPPTTTSAFVELSTTSHGSPS------STPTTHFSASSTTLG 4519
Query: 1767 KRDIVEELSALKQLTQTTHTDKVPGDEDKGINVFRETAKQKLDPAASVTGSKRQPRTPKG 1826
+ EE + + T T P + E+ P ++ T + T G
Sbjct: 4520 RS---EESTTVHSSPVATATTPSPARSTTS-GLVEESTTYHSSPGSTQTMHFPESNTTSG 4575
Query: 1827 KAQP--LEDLAGLKELFQTPICT----DKPTTHEKTTKIACRSPQPDPVGTPTIFKPQSK 1880
+ + + + P T ++PT++ + + PD T + +S
Sbjct: 4576 RGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDS-STTSGRSEEST 4634
Query: 1881 RSLRKADVEEESLALRKRTPSVGKAMDTPKPAGGDEKDMKAFMGTPVQKLDLPGNLPGSK 1940
S D + + T SV T P + A G+ PG S
Sbjct: 4635 ASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTT----PGLSEKST 4690
Query: 1941 RWPQTPKEKAQALEDLAGFKELFQTPGTDKPTTDEKTTKIACKSPQPDPVDTPASTKQRP 2000
+ +P F T ++E TT PV T +T P
Sbjct: 4691 TFHSSPSSTPTTH---------FSASSTTLGRSEESTTV------HSSPVAT--ATTPSP 4733
Query: 2001 KRNLRKADVEEEFLALRKRTPSAGKAMDTPKPAVSDEKN--INTFVETPVQKLDLLGNLP 2058
R+ VEE +P + + M P+ + + ++ T + + +
Sbjct: 4734 ARSTTSGLVEES--TAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTT 4791
Query: 2059 GSKRQPQTPKEKAEALEDLVGFKELFQTPGHTEESMTDDKITEVSCKSPQPESFKTSRSS 2118
+ + T + F E T G +EES + + +P P F TS
Sbjct: 4792 SALVEEPTSYHSSPGSIATTHFPESSTTSGRSEESTASHSSPDTNGITPLPAHFTTSGRI 4851
Query: 2119 KQRLKIPLVKVDMKEEPLAVSKLTRTSGETTQTHTEPTGDSKSIKAFKESPKQILDPA-- 2176
+ + M+ T+ +T T + S + + SP Q L PA
Sbjct: 4852 AESTTFYISPGSME-----------TTLASTATTPGLSAKSTILYSSSRSPDQTLSPASM 4900
Query: 2177 --ASVTGSRRQLRTRKEKARALEDLVDFKELFSAPGHTEESMTI-DKNTKIPCKSPPPEL 2233
+S++G L ++ E F + G ++ES T K P +
Sbjct: 4901 TSSSISGEPTSLYSQAESTHT----TAFPASTTTSGLSQESTTFHSKPGSTETTLSPGSI 4956
Query: 2234 TDTATSTKRCPKTRPRKEVKEELSAVERLTQT----SGQSTHTHKEPASGDEGIKVLKQR 2289
T TS+ T P + LS V + T S +ST + P S +
Sbjct: 4957 T---TSSFAQEFTTPHSQPGSALSTVSPASTTVPGLSEESTTFYSSPGSTE-----TTAF 5008
Query: 2290 AKKKPNPVEEEPSRRRPRAPKEKAQPLEDLAGFTELSETSGHTQESLTAGKATKIPCESP 2349
+ + + S P +P L T++ + S S A T +P S
Sbjct: 5009 SHSNTMSIHSQQSTPFPDSPGFTHTVLPATLTTTDIGQESTAFHSSSDATGTTPLPARST 5068
Query: 2350 PLEVV 2354
++V
Sbjct: 5069 ASDLV 5073
Score = 47.8 bits (112), Expect = 2e-04
Identities = 346/1752 (19%), Positives = 535/1752 (30%), Gaps = 266/1752 (15%)
Query: 996 PGHTEEAVAAGKTTKMPCESSPPESADTPTSTRR----QPKTPLEKRDVQKELSALKKLT 1051
PG T A + K+T P+ +P T + T R A T
Sbjct: 268 PGSTTTAGLSEKSTTFYSSPRSPDRTLSPARTTSSGVSEKSTTSHSRPGPTHTIAFPDST 327
Query: 1052 QTSG---ETTHTDKVPGGEDKSINAFRETAKQKLDPAASVTGSKRHPKTKEKAQPLEDLA 1108
G E+T + +PG D +++ T + + S + KT + +
Sbjct: 328 TMPGVSQESTASHSIPGSTDTTLSPGTTTPSSLGPESTTFHSSPGYTKTT-RLPDNTTTS 386
Query: 1109 GLKELFQTPV--CTDKP-TTHEKTTKIACRSQPDPVDTPTSSKPQSKRSLRKVDVEEEFF 1165
GL E TPV T P TT ++ +P + SSK S +
Sbjct: 387 GLLEA-STPVHSSTGSPHTTLSPSSSTTHEGEPTTFQSWPSSKDTSPAPSGTTSAFVKLS 445
Query: 1166 ALRKRTPSAGKAMHTPKPAVSGEKNIYAFMGTPVQKLDLTENLTGSKRRLQTPK--EKAQ 1223
+PS+ H + S ++ TPV + T R T E++
Sbjct: 446 TTYHSSPSSTPTTHF---SASSTTLGHSEESTPVHSSPVATATTPPPARSATSGHVEEST 502
Query: 1224 ALEDLAG------FKELFQTRGHTEESMTNDKTAKVACKSSQPDPDKNPASSKRRLKTSL 1277
A G F E T GH+EES T + KSS P A + +SL
Sbjct: 503 AYHRSPGSTQTMHFPESSTTSGHSEESATFHGST-THTKSS--TPSTTAALAHTSYHSSL 559
Query: 1278 GKVGVKEELLAVGKLTQTSGETTHTHTEPTGDGKS--MKAFMESPKQILDSAASLTGSKR 1335
G S ETTH T G+S KA SP + + +
Sbjct: 560 G-----------------STETTHFRDSSTISGRSEESKASHSSPDAMATTVLPAGSTPS 602
Query: 1336 QLRTPKGKSEVPEDLAGFIELFQTPSHTKESMTNEKTTKVSYRASQPDLVDTPTSSKPQP 1395
L G S +G +E P T + +EK+T PD P
Sbjct: 603 VL---VGDSTPSPISSGSMETTALPGSTTKPGLSEKSTTFYSSPRSPDTTHLPA------ 653
Query: 1396 KRSLRKADTEEEFLAFRKQ---TPSAGKAMHTPKPAVGEEKDINTFLGTPVQKLDQPGNL 1452
S+ + EE + T + T P + +E + P PG+
Sbjct: 654 --SMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQESTASHSSPGPTDTTLSPGST 711
Query: 1453 ---------------PGS--------NRRLQTRKEKAQALEELTGFRELFQTPCTDNPTT 1489
PGS N E + + T +P
Sbjct: 712 TASSLGPEYTTFHSRPGSTETTLLPDNTTASGLLEASMPVHSSTRSPHTTLSPAGSTTRQ 771
Query: 1490 DEKTTKKILCKSPQSDPAD--------TPTNTKQRPKRSLKKADVE---------EEFLA 1532
E TT S + PA P+ T S+ + EE
Sbjct: 772 GESTTFHSWPSSKDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTT 831
Query: 1533 FRKLTPSAGKAMHTPKA--AVGEEKDINTFVGTPVEKLDLLGNLPGSKRRPQTPKEKAKA 1590
+ +P + + MH P++ G ++ T + + + + T +
Sbjct: 832 YHS-SPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPG 890
Query: 1591 LEDLAGFKELFQTPGHTEESMTDDKITEVSCKSPQPDPVKTPTSSKQRLKISLGKVGVKE 1650
F + T G +EES + + P T + + ++
Sbjct: 891 STATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMET 950
Query: 1651 EVLPVGKLTQTSGKTTQTHRETAGDGKSIKAFKESAKQ---MLDPAN-YGTGMERWPRTP 1706
LP G TT T G + F S + L PA+ +G+ T
Sbjct: 951 TALP--------GSTT-----TPGLSERSTTFHSSPRSPATTLSPASTTSSGVSEESTTS 997
Query: 1707 KEEAQSLEDLAGFKELFQTPDHTEESTTD-------DKTTKIACKSPPPESMDTPTSTRR 1759
+ S A F + TP + STT D T A + S ++ TS
Sbjct: 998 RSRPGSTHTTA-FPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSS 1056
Query: 1760 RPKTPLGKRDIVEELSALKQLTQTTHTDKVPGDEDKGINVFRETAKQKLDPAASV---TG 1816
T + Q + T H++ PG + T+ ++ + V TG
Sbjct: 1057 SGSTDTALSPGSTTALSFGQESTTFHSN--PGSTHTTLFPDSTTSSGIVEASTRVHSSTG 1114
Query: 1817 SKRQPRTPKGKAQPLEDLAGLKELFQTPICTDKPTTHEKTTKIACRSPQPDPVGTPTIFK 1876
S R +P P L G FQ T +TH TT P P T T
Sbjct: 1115 SPRTTLSPASSTSP--GLQGESTAFQ----THPASTH--TT--------PSPPSTAT--- 1155
Query: 1877 PQSKRSLRKADVEEESLALRKRTPSVGKAMDTPKPAGGDEKDMKAFMGTPVQKLDLPGNL 1936
A VEE + R + G + F +P D G
Sbjct: 1156 ---------APVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSP----DASGTT 1202
Query: 1937 PGSKRWPQTPKEKAQALEDLAGFKELFQTPG-TDKPTTDEKTTKIACKSPQPDPVDTPAS 1995
P S + + ++ G E+ PG T P E +T P +PAS
Sbjct: 1203 PSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPAS 1262
Query: 1996 TKQRPKRNLRKADVEEEFLALRKR---TPSAGKAMDTPKPAVSDE-----KNINTFVETP 2047
+ V EE R + T S T P +S+E + ET
Sbjct: 1263 --------MTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSRGSTETT 1314
Query: 2048 VQKLDLLGNLPGSKRQPQTPKEKAEALEDLVGFKELFQTPGHTEESMTDDKITEVSCKSP 2107
V ++ G +P T + + + F E T G TEES T + S ++
Sbjct: 1315 VFPHSTTTSVHG--EEPTTFHSRPASTHTTL-FTEDSTTSGLTEES-TAFPGSPASTQTG 1370
Query: 2108 QPESFKTSRSSKQRLKIPLV--KVDMKEEPL-----------AVSKLTRTSGETTQTHTE 2154
P + T+ ++ P K P S+L+ +S ETT
Sbjct: 1371 LPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGS 1430
Query: 2155 PTGDSKSIKA-----FKESPKQILDPAASVT------GSRRQLRTRKEKARALEDLVDFK 2203
PT S S K+ SP L PA + + S + A D
Sbjct: 1431 PTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTS 1490
Query: 2204 ELFSAPGHTEESMTIDKNTKIPCKSPPPELTDTATSTKRCP-----KTRPRKEVKEELSA 2258
+L P + S + T P + L +T+ P P + L
Sbjct: 1491 DLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVE 1550
Query: 2259 VERLTQTSGQSTHTHKEPASG-DEGIKVLKQRAKKKPNPVEEEPSRRRPRAPKEKAQPLE 2317
T +S S HT PAS G++ + P+ + PS P A P+E
Sbjct: 1551 ASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPS-----PPGTTAAPVE 1605
Query: 2318 ------------DLAGFTELSETSGHTQESLT--------------AGKATKIPCESPPL 2351
F+ S T G ++ES T AT + P
Sbjct: 1606 VSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTT 1665
Query: 2352 EVVDTTASTKRHLRTRVQKVQVKEEPSAVKFTQTSGETTDADKEPAGEDKGIKALKESAK 2411
+ + ++ L + E+ + + S +TT + ++ ++
Sbjct: 1666 SPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSR 1725
Query: 2412 QTPAPAASVTGSRRRPRAPRESAQAIEDLAGFKDPAAGHTEESMTDDKTTKIPCKSSPEL 2471
+ GS P +ES A P G T+ +++ TT PE
Sbjct: 1726 PGSTHTTAFPGSTTMPGVSQEST------ASHSSP--GSTDTTLSPGSTT--ASSLGPES 1775
Query: 2472 EDTATSSKRRPRTRAQKVEVKEELLAVGKLTQTSGETTHTDKEPVG----EGKGTKAFKQ 2527
+S T LL +S + HT P G +G+ T
Sbjct: 1776 TTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSW 1835
Query: 2528 P-AKRKLDAEDVIGSRRQPRAPKEKAQPLE-DLASFQELSQTPGHTEEL----ANGAADS 2581
P +K + A S + P F S T G +EE ++ A +
Sbjct: 1836 PSSKDTMPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATA 1895
Query: 2582 FTSAPKQTPDSG 2593
T +P ++ SG
Sbjct: 1896 TTPSPARSTTSG 1907
Score = 34.7 bits (78), Expect = 1.4
Identities = 112/539 (20%), Positives = 181/539 (33%), Gaps = 73/539 (13%)
Query: 2139 SKLTRTSGETTQT--HTEPTGDSKSIKAFKESPK---QILDPAASVTGSRRQLRTRKEKA 2193
S +T S ETT T G S+ F SP+ + L PA + + + T
Sbjct: 255 SPITSASMETTALPGSTTTAGLSEKSTTFYSSPRSPDRTLSPARTTSSGVSEKSTTSHSR 314
Query: 2194 RALEDLVDFKELFSAPGHTEES-----------MTIDKNTKIPCKSPPPELTDTATSTKR 2242
+ F + + PG ++ES T+ T P S PE T +S
Sbjct: 315 PGPTHTIAFPDSTTMPGVSQESTASHSIPGSTDTTLSPGTTTP-SSLGPESTTFHSSPGY 373
Query: 2243 CPKTR-PRKEVKEELSAVERLTQTSGQSTHTHKEPASG--DEGIKVLKQ----RAKKKPN 2295
TR P L +S S HT P+S EG Q P
Sbjct: 374 TKTTRLPDNTTTSGLLEASTPVHSSTGSPHTTLSPSSSTTHEGEPTTFQSWPSSKDTSPA 433
Query: 2296 PVEEEPSRRRPRAPKEKAQPLEDLAGFTELSETSGHTQESLTAGKATKIPCESPPLEVVD 2355
P + + + F+ S T GH++ES + +PP
Sbjct: 434 PSGTTSAFVKLSTTYHSSPSSTPTTHFSASSTTLGHSEESTPVHSSPVATATTPP----P 489
Query: 2356 TTASTKRHLRTRVQKVQVKEEPSAVKFTQTSGETTDADKEPAGEDKGIKALKESAKQTPA 2415
++T H+ + + F ++S TT E + G + + TP+
Sbjct: 490 ARSATSGHVEESTAYHRSPGSTQTMHFPESS--TTSGHSEESATFHG--STTHTKSSTPS 545
Query: 2416 PAASVTGSRRRPRAPRESAQAIEDLAGFKDPA--AGHTEESMTDDK------TTKIPCKS 2467
A++ S+ + F+D + +G +EES TT +P S
Sbjct: 546 TTAALA------HTSYHSSLGSTETTHFRDSSTISGRSEESKASHSSPDAMATTVLPAGS 599
Query: 2468 SPE--LEDTATS--SKRRPRTRAQKVEVKEELLAVGKLT----QTSGETTHTDKEPVGEG 2519
+P + D+ S S T A + L+ T S +TTH G
Sbjct: 600 TPSVLVGDSTPSPISSGSMETTALPGSTTKPGLSEKSTTFYSSPRSPDTTHLPASMTSSG 659
Query: 2520 ---KGTKAFKQPAKRKLDAEDVIGSRRQPRAPKEKAQPLEDLASFQELSQTPGHTE-ELA 2575
+ T + +P A GS P +E +PG T+ L+
Sbjct: 660 VSEESTTSHSRPGSTHTTA--FPGSTTMPGLSQESTAS----------HSSPGPTDTTLS 707
Query: 2576 NGAADSFTSAPKQTPDSGKPLKISRRVLRAPKVEPVGDVVSTRDPVKSQSKS-NTSLPP 2633
G+ + + P+ T +P +L P ++ PV S ++S +T+L P
Sbjct: 708 PGSTTASSLGPEYTTFHSRPGSTETTLL--PDNTTASGLLEASMPVHSSTRSPHTTLSP 764
>gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e
[Homo sapiens]
Length = 1451
Score = 60.1 bits (144), Expect = 3e-08
Identities = 291/1487 (19%), Positives = 507/1487 (34%), Gaps = 212/1487 (14%)
Query: 1429 VGEEKDINTFLGTPVQKLDQPGNLPGSNRRLQTRKEKAQALEELTGFRELFQTPCTDNPT 1488
V E+ FL PV LD + ++ RK KA+ L + P + + +
Sbjct: 30 VKEQSGQKCFLAQPVTLLDIYTHWQQTSEL--GRKRKAEEDAALQAKKTRVSDPISTSES 87
Query: 1489 TDE---------KTTKKILCKSPQSDPADTPTNTKQRPKRSLKKADVEEEFLAFRKLTPS 1539
++E K T ++ + AD P++ K++ K +KA + P+
Sbjct: 88 SEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNSMPH----PA 143
Query: 1540 AGKAMHTPKAAVGEEKDINTFVGTP-VEKLDLLGNLP--GSKRRPQTPKEKAKALEDLAG 1596
GK + + K T V + + G++P G+ +P G
Sbjct: 144 TGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKP--------------G 189
Query: 1597 FKELFQTPGHTEESMTDDKITEVSCK-SPQPDPVK-----TPTSSKQRLKISLGKVG--- 1647
Q +E++ + T+V K S +P VK T S ++ + GKVG
Sbjct: 190 MVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVT 249
Query: 1648 --VKEEVLPVGKLTQTSGKTTQTHRE--------TAGDGKSIKAFKE--SAKQMLDPANY 1695
VK LP K + + +++ E AG +KA ++ + PA
Sbjct: 250 PQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKG 309
Query: 1696 GTGMERWPRTP-KEEAQSLEDLAGFKELFQTPDHTEESTTDDKT--------TKIACKSP 1746
G P P K A + + AG E E S ++++T K + K+
Sbjct: 310 TPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTS 369
Query: 1747 PPESMDTPTSTRRR----PKTPLGKRDIVEELSALKQLTQTTHTDKVPGDEDKGINVFRE 1802
+ P R P P V + A K+ + + + E++ +
Sbjct: 370 QVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKP 429
Query: 1803 TAKQKLDPAASVTGSKRQPR-----TPKGKAQPLEDLAGLKELFQTPICTDKPTTHEKTT 1857
+ K AAS +K PR P K P + + + + + + ++
Sbjct: 430 SGKAPQVRAASAP-AKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREA 488
Query: 1858 KIACRSPQPDPVGTPTIFKPQSKRSLRKADVEEESLALRKRTPSVGKAMDTPKPAGGDEK 1917
A + Q P+G KP S + + K P+ A G E+
Sbjct: 489 LAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQ-----VGKWEE 543
Query: 1918 DMKAFMGTPVQKLDLPGNLPGSKRWPQTPKEKAQALEDLAGFKELFQTPGTDKPTTD--E 1975
D ++ D + P A A E G + Q T P +
Sbjct: 544 DSESSSEESSDSSD-----------GEVPTAVAPAQEKSLG--NILQAKPTSSPAKGPPQ 590
Query: 1976 KTTKIACKSPQPDPVDTPASTKQRPKRNLRKADVEEEFLALRKRTPSAGKAMDTPKPAVS 2035
K +A + P+D S+++ AD EE A+ A A+ P+
Sbjct: 591 KAGPVAVQVKAEKPMDNSESSEESSD----SADSEEAPAAMT--AAQAKPALKIPQTKAC 644
Query: 2036 DEKNINTFVETPVQKLDLLGNLPGSKRQPQTPKEKAEALEDLVGFKELFQTPGHTEESMT 2095
+K NT V + + P +P + A+ G + + +EES +
Sbjct: 645 PKKT-NTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAG--GTQRPAEDSSSSEESDS 701
Query: 2096 DDKITEVSCKSPQPESFKTSRSSKQRLKIPLVKVDMKE---EPLAVSKLTRTSGETTQTH 2152
+++ T ++ Q ++S + L++ V +K + A +T TQ
Sbjct: 702 EEEKTGLAVTVGQ------AKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVK 755
Query: 2153 TEPTGDSKSIKAFKESPKQILDPAASVTGSRR-QLRTRKEKARALEDLVDFKELFSAPGH 2211
E DS+S + +S + PA T ++ Q + ARA K SAPG
Sbjct: 756 AEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARA----PSAKGTISAPGK 811
Query: 2212 TEESMTIDKNTKIPCKSPPPELTDTATSTKRCPKTRPRKEVKEELSAVERLTQTSGQSTH 2271
+ K PP +T R P + P K +A + T S
Sbjct: 812 VVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVG-KAVATAAQAQTGPEEDSGS 870
Query: 2272 THKEPASGDEGIKVLKQRAKKKPN-------PVEEEPSRRRPRAPKEKAQPL-------E 2317
+ +E S +E + + + K + P +E P + P K P +
Sbjct: 871 SEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQD 930
Query: 2318 DLAGFTELSETSGHTQESLTAGKATKIPCESPPLEVVDTTASTKRHLRTRVQKVQVKEEP 2377
D +E S++ G ++T+ + K PPL VD S T Q Q P
Sbjct: 931 DSGSSSEESDSDGEAPAAVTSAQVIK-----PPLIFVDPNRSPAGPAATPAQ-AQAASTP 984
Query: 2378 SAVKFTQT-----SGETTDADKEPAGE--DKGIKA---LKESAKQTPAPAASVTGSRRRP 2427
+ +++ S E+ D D PA + GI+ +A AP AS+ G+
Sbjct: 985 RKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSK 1044
Query: 2428 RAPRES--------AQAIEDLAGFKDPAAGHTEESMTDDKTTKIPCKSSPEL-------- 2471
+ R S A ++ G PA S+ T K+ PE+
Sbjct: 1045 ESSRISDGKKQEGPATQVDSAVGTL-PATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPE 1103
Query: 2472 -----EDTATSSKRRPRTRAQKVEVKEELLAVGK--------LTQTSGETTHTDKEPVGE 2518
ED++ SS K VG + +T+ E++ D +
Sbjct: 1104 SSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETLVEETAAESSEDDVVAPSQ 1163
Query: 2519 G--KG------TKAFKQPAKR--KLDAEDVIGSRRQPRAPKEKAQPLEDLASFQELSQTP 2568
G T A Q +K KLD+ + S + + Q + + LS
Sbjct: 1164 SLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKT 1223
Query: 2569 GHTEELANGAADSFTSAPKQTPDS-----------------GKPLKISRRVLRAPKVEPV 2611
G +E A+G + PK+ + G+P ++ ++A V+ +
Sbjct: 1224 GG-KEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVL 1282
Query: 2612 GDVVST-RDPVKSQSKSNTSLPPLPFKRGGGKDGSVTGT---KRLRCMPAPE----EIVE 2663
+++ R V +K ++ KR D T K+ + + A E +
Sbjct: 1283 TELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSP 1342
Query: 2664 ELPASKKQRVAPRARGKSSEPVVIMKRSLRTSAKRIEPAEELNSNDMKTNKEEHKLQDSV 2723
E ++ + A R + K SL + + EP EEL + S
Sbjct: 1343 EKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSK 1402
Query: 2724 PENKGISLRSRRQNKTEAEQQITEVFVLAERIEINRNEKKPMKTSPE 2770
E K R + + K E +++ + + +KK KT+ +
Sbjct: 1403 KEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKKTAEQ 1449
Score = 52.0 bits (123), Expect = 9e-06
Identities = 129/674 (19%), Positives = 239/674 (35%), Gaps = 126/674 (18%)
Query: 2230 PPELTDTATSTKRCPKTRPRKEVKEELSAVERLTQTSGQSTHTHKEPASGDEGIKVLKQR 2289
P L D T ++ + +++ +E+ + + T+ S + + S +E + +
Sbjct: 43 PVTLLDIYTHWQQTSELGRKRKAEEDAALQAKKTRVSDPISTSE----SSEEEEEAEAET 98
Query: 2290 AKKKPNPVEEEPS---RRRPRAPKEKAQPLEDLAGFTELS---ETSGHTQESLTAGKATK 2343
AK P S P + KEKA+ + AG T S +G T +L +GK+ +
Sbjct: 99 AKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPR 158
Query: 2344 IPCESPPLEVVDTTASTKRH-------LRTRVQKVQVKEEPSAVKFTQTSGETTDADKEP 2396
E P + T+ + V + S+ + T +S + TD + +P
Sbjct: 159 KSAE--PSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKP 216
Query: 2397 AGEDKGIKALKESAKQTPAPAASVTGSRRRPRAPRESAQAIEDLAGFKDPAAGHTEESMT 2456
+ + +KA S K++PA R+ AP + + G P A
Sbjct: 217 SVKPAQVKASSVSTKESPA--------RKAAPAPGKVGDVTPQVKGGALPPA-------- 260
Query: 2457 DDKTTKIPCKSSPELEDTATSSKRRPRTRAQKVEVKEELLAVGKLTQTSGETTHTDKEPV 2516
K K P + S E+ + S + P +V+ E++L V + + T P
Sbjct: 261 --KRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPA 318
Query: 2517 GEGKGTKAFKQPAKRKLDAEDVIGSRRQPRAPKEKAQPLEDLASFQELSQTPGHTEELAN 2576
GK + S+ + P+E ++
Sbjct: 319 PPGKA---------------GAVASQTKAGKPEEDSE----------------------- 340
Query: 2577 GAADSFTSAPKQTPDSGKPLKISRRVLRAPKVEPVGDVVSTRDPVKSQSKSNTSLPPLPF 2636
S+ +++ DS + ++ +L+A V + P K +S + P P
Sbjct: 341 -------SSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAK-ESPRKGAAPAPPG 392
Query: 2637 KRGGGKDGSVTGTKRLRCMPAPEE--IVEELPA-SKKQRVAPRARGKSSEPVVIMKRSLR 2693
K G + G + + EE EE PA +K AP+ R S+ K S R
Sbjct: 393 KTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAP----AKESPR 448
Query: 2694 TSAKRIEPAEELNSNDMKTNKEEHKLQDSVPENKGISLRSRRQNKTEAEQQITEVFVLAE 2753
A P KT ++Q + +++ +E+ ++ LA
Sbjct: 449 KGAAPAPP--------RKTGPAAAQVQVG---------KQEEDSRSSSEESDSDREALA- 490
Query: 2754 RIEINRNEKKPMKTSPEMDI-----QNPDDGARKPIPRDKV---TENKRCLRSARQNESS 2805
+N + KP+ SP++ P P+P KV T + + + +ESS
Sbjct: 491 --AMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESS 548
Query: 2806 QPKVAEESGGQKSAKVLMQNQKGKGEAGNSDSMCLRSRKTKSQPAASTLESKSVQRVTRS 2865
+ ++ S G+ V +K G + K S PA + V
Sbjct: 549 SEESSDSSDGEVPTAVAPAQEKSLGN--------ILQAKPTSSPAKGPPQKAGPVAVQVK 600
Query: 2866 VKRCAENPKKAEDN 2879
++ +N + +E++
Sbjct: 601 AEKPMDNSESSEES 614
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 59.3 bits (142), Expect = 5e-08
Identities = 164/847 (19%), Positives = 297/847 (35%), Gaps = 104/847 (12%)
Query: 2060 SKRQPQTPKEKAEALEDLVGFKELFQTPGHTEESMTDDKITEVSCKSPQPESFKTSRSSK 2119
S R P TPK+K K+ + G ES + + + S K + S S+ K
Sbjct: 179 SSRSP-TPKQKK---------KKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESKKRK 228
Query: 2120 QRLKIPLVKVDMKEEPLAVSKLTRTSGETTQTHTEPTGDSKSIKAFKESPKQILDPAASV 2179
R P K K++ S+ T + ++ + H + DS S S +
Sbjct: 229 HRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHT 288
Query: 2180 TGSRRQLRTRKEKARALEDLVDFKELFSAPGHTEESMTIDKNTKIPCKSPPPELTDTATS 2239
T + + R D FS PG T P +TAT
Sbjct: 289 TALAGRSPSPASGRRGEGDAP-----FSEPGTTSTQR--------------PSSPETATK 329
Query: 2240 TKRCPKTRPRKEVKEELSAVERLTQTSGQSTHTHKEPASGDEGIKVLKQRAKKKPNPVEE 2299
P K+ KE+ + S + + T EP + +L +R P P+
Sbjct: 330 QPSSPYEDKDKDKKEKSAT---RPSPSPERSSTGPEPPAPTP---LLAERHGGSPQPLAT 383
Query: 2300 EPSRRRPRAPKEKAQPLEDLAG--FTELSETSGHTQESLTAGKATKI------------- 2344
P + P P +A P D + E S ++ S + + TK+
Sbjct: 384 TPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKP 443
Query: 2345 -PCESPPLEVVDTTASTKR-HLRTRVQKVQVKEEPSAVKFTQTSGETTDADKEPAGEDKG 2402
P E+ + S R H R + K + T + PA +G
Sbjct: 444 APAPGSHREISSSPTSKNRSHGRAKRDK----------SHSHTPSRRMGRSRSPATAKRG 493
Query: 2403 IKALKESAKQTPAPAASVTGSRRRPRAPRESAQAIEDLAGFKDPAAGHTEESMTDDKT-- 2460
+ K+ + + S R R +++ + + P S +
Sbjct: 494 RSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGR 553
Query: 2461 TKIPCKSSPELEDTATSSKRRPRTRAQKVEVKEELLAVGKLTQTSGETTHTDKEPVGEGK 2520
++ + AT + R RT A++ + A + +++ T + +
Sbjct: 554 SRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPA-RRRSRSRTPTRRRSRSRTPARR 612
Query: 2521 GTKAFKQPAKRKLDAEDVIGSRRQPRAPKEKAQPLEDLASFQELSQTPGHTEELANGAAD 2580
G + PA+R+ + R + R+P + S + S+TP G +
Sbjct: 613 GRSRSRTPARRRSRTRSPVRRRSRSRSPARR--------SGRSRSRTPAR-----RGRSR 659
Query: 2581 SFTSAPKQTPDSGKPLKISRRVLRAPKVEPVGDVVS-TRDPVKSQSKSNT------SLPP 2633
S T A + S P +RR R+ P S +R P + +S+S + S
Sbjct: 660 SRTPARRGRSRSRTP---ARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSR 716
Query: 2634 LPFKRGGG------KDGSVTGTKRLRCMPAPEEIVEELPASKKQRVA-PRARGKSSEPVV 2686
P +RG K+ S T +R R +PE + + + + ++ PR++ KS +
Sbjct: 717 TPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSR---L 773
Query: 2687 IMKRSLRTSAKRIEPAEELNSNDMKTNKEEHKLQDSVPENKGISLRS---RRQNKTEAEQ 2743
++RSL S+ + + ++ + K + P + S S ++++KT + Q
Sbjct: 774 SLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQ 833
Query: 2744 QITEVFVLAERIEINRNEKKPMKTSPEMDIQNPDDGARKPIPRDKVTENKRCLRSARQNE 2803
+ +++ ++ TSP+ + Q+ R E K S
Sbjct: 834 SHSSSSP-HPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCS 892
Query: 2804 SSQPKVAEESGGQKSAKVLMQNQKGKGEAGNSDSMCLRSRKTKSQPAASTLESKSVQRVT 2863
S P + S + + + + K +A S RS S P+ S + S++ R +
Sbjct: 893 GSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQ--RSHSGSSSPSPSRVTSRTTPRRS 950
Query: 2864 RSVKRCA 2870
RSV C+
Sbjct: 951 RSVSPCS 957
Score = 54.3 bits (129), Expect = 2e-06
Identities = 148/773 (19%), Positives = 266/773 (34%), Gaps = 98/773 (12%)
Query: 1950 AQALEDLAG--FKELFQTPGTDKPTTDEKTTKIACKSPQPDPVDTPASTKQRPKRNLRKA 2007
++ EDL G +L P D +++ + PD V+ + +
Sbjct: 1349 SEVKEDLNGPFLNQLETDPSLDMKEQSTRSSGHSSSELSPDAVEKAGMSSNQ-------- 1400
Query: 2008 DVEEEFLALRKRTPSAGKAMDTPKPAVSD--------------EKNINTFVETPVQKLDL 2053
+ L RTPS ++ P + D + TP + L
Sbjct: 1401 SISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTPSRRSRSGSSPGLRDGSGTP-SRHSL 1459
Query: 2054 LGNLPGSKRQPQTPKEKAEALEDLVGFKELFQTPGHTEESMTDDKITEVSCKSPQPESFK 2113
G+ PG K P+TP + K L QTP S + ++ C +PQ E
Sbjct: 1460 SGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPRPRSRSPSSPELNN-KCLTPQRERSG 1518
Query: 2114 TSRSSKQRLKIPLVKVDMKEEPLAVSKLTRTSGETTQTHTEPTGDSKSIKAFKESPKQIL 2173
+ S Q+ + PL SG + + +P+ + SP
Sbjct: 1519 SESSVDQKT--------VARTPLGQRS---RSGSSQELDVKPSASPQERSESDSSPD--- 1564
Query: 2174 DPAASVTGSRRQLRTRKEKARALEDLVDFKELFSAPGHTEESMTIDKNTKIPCKSPPPEL 2233
S +R LR R + E VD K S P + + + K
Sbjct: 1565 ----SKAKTRTPLRQRSRSGSSPE--VDSKSRLS-PRRSRSGSSPEVKDKPRAAPRAQSG 1617
Query: 2234 TDTATSTKR-CPKTRPRKEVKEELSAVERLTQTSGQSTHTHKEPASGDEGIKVLKQRAKK 2292
+D++ K P+ PR+ S + ST + E K R
Sbjct: 1618 SDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPP-----KSRTARRGS 1672
Query: 2293 KPNPVEEEPSRRRPRAPKEKAQPLEDLAGFTELSETSGHTQESLTAGKATKIPCESPPLE 2352
+ +P + SR PR ++ P EL+ + ++ S +A + + +PP
Sbjct: 1673 RSSPEPKTKSRTPPRRRSSRSSP--------ELTRKARLSRRSRSASSSPETRSRTPPRH 1724
Query: 2353 VVDTTASTKRHLRTRVQKVQVKEEPSAVKFTQTSGETTDADKEPAGEDKG-IKALKESAK 2411
+ S+ + + + + S+ + TS +P G + ++ +E +
Sbjct: 1725 RRSPSVSSPEPAE-KSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTR 1783
Query: 2412 QT---PAPAASVTGSRRRPRAPRESAQAIEDLAGFKDPAAGHTEESMTDDKTTKIPCKSS 2468
T +S + SRRR R+ S G +G+ S ++++ +
Sbjct: 1784 TTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGG-----SGYHSRSPARQESSRTSSRRR 1838
Query: 2469 PELEDTATSSKRRPRTRAQKVEVKEELLAVGKLTQTSGETTHTDKEPVGEGKGTKAFKQP 2528
T +S++R R+R K T + + P+ + +++ P
Sbjct: 1839 RGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRS----RTPLISRRRSRSRTSP 1894
Query: 2529 AKRKLDAEDVIGSRRQPRAPKEKAQPLEDLASFQELSQTPGHTEELANGAADSFTSAPK- 2587
R+ +RR+ R+ +A P+ S S+TP T + + +
Sbjct: 1895 VSRRRSRSRTSVTRRRSRS---RASPVSRRRS---RSRTPPVTRRRSRSRTPTTRRRSRS 1948
Query: 2588 QTPDSGKPLKISRRVLRAPKVEPVGDVVSTRDPVKSQSKSNTSLPPLPFKRGGGKDGSVT 2647
+TP P+ R R P V T + +S+S TS P+ +R + VT
Sbjct: 1949 RTP----PVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTS--PVTRRRSRSRTSPVT 2002
Query: 2648 GTKRLRCMPAP---EEIVEELPASKKQR------VAPRARGKSSEPVVIMKRS 2691
+R R +P P + ++R + PR R +S P+ I +RS
Sbjct: 2003 -RRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRS 2054
Score = 52.8 bits (125), Expect = 5e-06
Identities = 298/1627 (18%), Positives = 544/1627 (33%), Gaps = 244/1627 (14%)
Query: 1140 PVDTPTSSKPQSKRSLRKVDVEEEFFALRKRTPSAGKAMHTPKPAVSGEKNIYAFMGTPV 1199
PV + S+ ++RS R R RTP+ + PA G TP
Sbjct: 630 PVRRRSRSRSPARRSGRS----------RSRTPARRGRSRSRTPARRGRSR----SRTPA 675
Query: 1200 QKLDLTENLTGSKR---RLQTPKEKAQALEDLA----GFKELFQTRGHTEESMTNDKTAK 1252
++ + + T ++R R +TP+ L Q RG + S ++
Sbjct: 676 RRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSR 735
Query: 1253 VACK----SSQPDPDKNPASSKRRLKTSLGKVGVKEELLAVGKLTQTSG---ETTHTHTE 1305
+ + +S P+ K+ SS+R S + K L L+ +S + + T
Sbjct: 736 TSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPR 795
Query: 1306 PTGDGKSM-KAFMESPKQILDSAASLTGSKRQLRTPKGKSEVPEDLAGFIELFQTPSHTK 1364
+ G S KA +P + S++S K++ +TP +S ++ P +
Sbjct: 796 RSRSGSSQPKAKSRTPPRRSRSSSS-PPPKQKSKTPSRQSHSSSSPHPKVKSGTPPR--Q 852
Query: 1365 ESMTNEKTTKVSYRASQPDLVDTPTSSKPQPKRSLRKADTEEEFLAFRKQTPSAGKAMHT 1424
S+T+ + + S + + S P P+ R + + S+ +
Sbjct: 853 GSITSPQANEQSVTPQRRSCFE----SSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQS 908
Query: 1425 PKPAVGEEKDINTFLGTPVQKLDQPGNLPGSNRRLQTRKEKAQALEELTGFRELFQTPCT 1484
P + + + + +P Q+ + P +R T R +PC+
Sbjct: 909 PSRSSSPQPKVKAII-SPRQRSHSGSSSPSPSR----------VTSRTTPRRSRSVSPCS 957
Query: 1485 DNPTTDEKTTKKILCKSPQSDPADTPTNTK-QRPKRSLKKADVEEEFLAFRKLTPSAGKA 1543
+ ++L + S + T K + P R + + + TP G +
Sbjct: 958 N-------VESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISP-YPKVKAQTPP-GPS 1008
Query: 1544 MHTPKAAVGEEKDINTFVGTPVEKLDLLGNLPGS---------------KRRPQTPKEKA 1588
+ K+ +EK ++ V + L L + S K + QT +
Sbjct: 1009 LSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPDHR 1068
Query: 1589 KALEDLAGFKELFQTPGHTEESMTDDKITEVSCKSPQPDPVKTPTSSKQRLKISLGKVGV 1648
+ ++P +S T K SP + + R + S + +
Sbjct: 1069 SDTSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSASPM-L 1127
Query: 1649 KEEVLPVGKLTQTSGKTTQTHRETAGDGKSIKAFKESAKQMLDP----ANYGTGMERWPR 1704
K + P Q+ + T + G+S ES ++M P A ++
Sbjct: 1128 KSGMSPEQSRFQSDSSSYPTVDSNSLLGQSRLETAESKEKMALPPQEDATASPPRQKDKF 1187
Query: 1705 TPKEEAQSLEDLAGFKELFQTPDHTEESTTDDKTTKIACKSPPPESMDTPT-STRRRPKT 1763
+P E FK+ +TP TK + P S D + +
Sbjct: 1188 SPFPVQDRPESSLVFKDTLRTPPRERSGAGSSPETKEQNSALPTSSQDEELMEVVEKSEE 1247
Query: 1764 PLGKRDIVEELSALKQLTQTTHTDKVPGDEDK---GINVFRETAKQKLDP------AASV 1814
P G+ I+ LS+ + T++ + P E++ + + + ++ L+ A+S
Sbjct: 1248 PAGQ--ILSHLSSELKEMSTSNFESSPEVEERPAVSLTLDQSQSQASLEAVEVPSMASSW 1305
Query: 1815 TGSKRQPRTPKGKAQPL-EDLAGLKELFQT--PICTDKPTTHEKTTKIACRSPQPDPVGT 1871
G P + PL E+ G F+ P+ T+ T K P + + T
Sbjct: 1306 GGPHFSPEHKELSNSPLRENSFGSPLEFRNSGPLGTEMNTGFSSEVKEDLNGPFLNQLET 1365
Query: 1872 -PTI-FKPQSKRSLRKADVEEESLALRK------------------RTPSVGKAMDTPKP 1911
P++ K QS RS + E A+ K RTPS ++ P
Sbjct: 1366 DPSLDMKEQSTRSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSP 1425
Query: 1912 A--------------GGDEKDMKAFMGTPVQKLDLPGNLPGSKRWPQTPKEKAQALEDLA 1957
G ++ GTP + L G+ PG K P+TP +
Sbjct: 1426 EMKDGLPRTPSRRSRSGSSPGLRDGSGTP-SRHSLSGSSPGMKDIPRTPSRGRSECDSSP 1484
Query: 1958 GFKELFQT--PGTDKPTTDEKTTKIACKSPQPDPVDTPASTKQRPKRNLRKADVEEEFLA 2015
K L QT P + P++ E K C +PQ + + +S Q+ V L
Sbjct: 1485 EPKALPQTPRPRSRSPSSPELNNK--CLTPQRERSGSESSVDQK--------TVARTPLG 1534
Query: 2016 LRKRTPSAGKAMDTPKPAVSDEKNINTFVETPVQKLDLLGNLPGSKRQPQTPKEKAEALE 2075
R R+ S+ + +D KP+ S ++ + + P SK + +TP +
Sbjct: 1535 QRSRSGSS-QELDV-KPSASPQERSES------------DSSPDSKAKTRTPLRQRSRSG 1580
Query: 2076 DLVGFKELFQTPGHTEESMTDDKITEVSCKSPQPESFKTSRSSKQRLKIPLVKVDMKEEP 2135
+ S + ++ + +P+ +S S K P P
Sbjct: 1581 SSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQS---GSDSSPEPKAP--------AP 1629
Query: 2136 LAVSKLTRTSGETTQTHTEPTGDSKSIKAFKESPKQILDPAASVTGSRRQLRTRKEKARA 2195
A+ + +R+ + P G S + + + PK RT + +R
Sbjct: 1630 RALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKS---------------RTARRGSR- 1673
Query: 2196 LEDLVDFKELFSAPGHTEESMTIDKNTKIPCKSPPPELTDTATSTKR------CPKTRPR 2249
S+P +S T + PELT A ++R P+TR R
Sbjct: 1674 -----------SSPEPKTKSRTPPRRRS---SRSSPELTRKARLSRRSRSASSSPETRSR 1719
Query: 2250 KEVKEELSAVERLTQTSGQSTHTHKEPASGDEGIKVLKQRAKK-KPNPVEEEPSRRRPRA 2308
+ S + + +S + + ++ K +R + P P + SR R R
Sbjct: 1720 TPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRR 1779
Query: 2309 PKEKAQPLEDLAGFTELSETSGHTQESLTAGKATK-------IPCESPPLEVVDTTASTK 2361
K + D +G ++ TS Q S + + T+ SP + T+S +
Sbjct: 1780 EKTRTTRRRDRSGSSQ--STSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRR 1837
Query: 2362 RHLRTRVQKVQVKEEPSAVKFTQTSGETTDADKEPAGEDKGIKALKESAKQTPAPAASVT 2421
R R+R K S T+ A + + + S +TP + +
Sbjct: 1838 RRGRSRTPPTSRKRSRS---------RTSPAPWKRSRSRASPATHRRSRSRTPLISRRRS 1888
Query: 2422 GSRRRPRAPRESAQAIEDLAGFKDPAAGHTEESMTDDKTTKIPCKSSPELEDTATSSKRR 2481
SR P + R S A + +T + + S +++RR
Sbjct: 1889 RSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRS---RSRTPTTRRR 1945
Query: 2482 PRTRAQKVEVKEELLAVGKLTQTSGETTHTDKEPVGEGKGTKAFKQPAKRKLDAEDVIGS 2541
R+R V + +T+ + + P+ + +++ P R+ S
Sbjct: 1946 SRSRTPPVTRRRSRSRTPPVTR---RRSRSRTSPITR-RRSRSRTSPVTRRRSR-----S 1996
Query: 2542 RRQPRAPKEKAQPLEDLASFQELSQTPGHTEELANGAADSFTSAPKQTPDSGKPLKISRR 2601
R P + + + S+TP + + P++ S PL I RR
Sbjct: 1997 RTSPVTRRRSRSRTSPVTRRRSRSRTP---PAIRRRSRSRTPLLPRKRSRSRSPLAIRRR 2053
Query: 2602 VLRAPKVEPVGDVVSTRDPV---------KSQSKSNTSLPPLPFKRGGGKDGSVT-GTKR 2651
G TR P S +S ++ PP G + V + R
Sbjct: 2054 SRSRTPRTARGKRSLTRSPPAIRRRSASGSSSDRSRSATPPATRNHSGSRTPPVALNSSR 2113
Query: 2652 LRCMPAP 2658
+ C P
Sbjct: 2114 MSCFSRP 2120
Score = 51.6 bits (122), Expect = 1e-05
Identities = 154/773 (19%), Positives = 271/773 (35%), Gaps = 141/773 (18%)
Query: 2187 RTRKEKARALEDLVDFKELFSAPGHTEES----------MTIDKNTKIPCKSPPPELTDT 2236
R R+ + R LE +E+ G+ E+ M ++K+ K P
Sbjct: 62 RKRRVELRCLE----LEEMMEEQGYEEQQIQEKVATFRLMLLEKDVNPGGKEETPGQRPA 117
Query: 2237 ATSTKRCPKTRPRKEVKEELSAVERLTQTSGQSTHTHKEPASGD--EGIKVLKQRAKKKP 2294
T T + + +K ERL G S ++ + +S D + KQ A + P
Sbjct: 118 VTETHQLAELNEKKN--------ERLRAAFGISD-SYVDGSSFDPQRRAREAKQPAPEPP 168
Query: 2295 NP---VEEEPSRRRPRAPKEKAQPLEDLAGFTELSETSGHTQESLTAGKATKIPCESPPL 2351
P V E S R P ++K + +D SE+S +E + K K ES
Sbjct: 169 KPYSLVRESSSSRSPTPKQKKKKKKKDRG---RRSESSSPRRERKKSSKKKKHRSESESK 225
Query: 2352 EVVDTTASTKRHLRTRVQKVQVKEEPSAVKFTQTSGETTDADKEPAGEDKGIKALKESAK 2411
+ + + K +++ +K + + ++ + +T AD + + ++ +AK
Sbjct: 226 KRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAK 285
Query: 2412 QTPAPAASVTGSRRRPRAPRESAQAIEDLAGFKDPAAGHTEESMTDDKTTKIPCKSSPEL 2471
++ G P + R E A F +P T+ + + TK P SSP
Sbjct: 286 ---THTTALAGRSPSPASGRRG----EGDAPFSEPGTTSTQRPSSPETATKQP--SSP-Y 335
Query: 2472 EDTATSSKRRPRTRAQKVEVKEELLAVGKLTQTSGETTHTDKEPVGEGKGTKAFKQPAKR 2531
ED K + TR S E + T EP PA
Sbjct: 336 EDKDKDKKEKSATR----------------PSPSPERSSTGPEP------------PAPT 367
Query: 2532 KLDAEDVIGS---------RRQPRAPKEKAQPLEDLASFQELSQTPGHTEELANGAADSF 2582
L AE GS ++P P +A P D P E+L
Sbjct: 368 PLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRD-------RSPPKSPEKLPQ------ 414
Query: 2583 TSAPKQTPDSGKPLKISRRVL---RAPKVEP-------VGDVVSTRDPVKSQSKSNTSLP 2632
+S+ + +P S +P K+SR +PK P + ++++ ++K + S
Sbjct: 415 SSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHS 474
Query: 2633 PLPFKRGG----------GKDGSVTGTKRLRCMPAPEEIVEELPASKKQRV-APRARGKS 2681
P +R G G+ S T TKR + A + R +P+ RG+S
Sbjct: 475 HTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRS 534
Query: 2682 SEPV-VIMKRSLRTSAKRIEPAEELNSNDMKTNKEEHKLQDSVPENKGIS---------- 2730
P RS T + + + ++ + + P +G S
Sbjct: 535 RSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRS 594
Query: 2731 -----LRSRRQNKTEAEQQITEVFVLAERIEINRNEKKPMKTSPEMDIQNPDDGARKPIP 2785
R R +++T A + + A R R+ + S ++ +R P
Sbjct: 595 RSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPAR 654
Query: 2786 RDKVTENKRCLRSARQNESSQPKVAEESGGQKS----AKVLMQNQKGKGEAGNSDSMCLR 2841
R + R AR+ S A SG +S + +++ + S S+ R
Sbjct: 655 RGR----SRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRR 710
Query: 2842 SRKTKSQP-----AASTLESKSVQRVTRSVKRCAENPKKAEDNVCVKKIRTRS 2889
R P + S+ E K+ R ++ R +P+ + + ++ R+ S
Sbjct: 711 GRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLS 763
Score = 48.5 bits (114), Expect = 9e-05
Identities = 110/597 (18%), Positives = 206/597 (34%), Gaps = 92/597 (15%)
Query: 2326 SETSGHTQESLT------AGKATKIPCESPPLEVVDTTASTKR-------HLRTRVQKVQ 2372
+ +SGH+ L+ AG ++ SP L+ V T S +R ++ + +
Sbjct: 1376 TRSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTP 1435
Query: 2373 VKEEPSAVKFTQTSGETTDADKEPAGEDKGIKALKESAKQTPAPAASVTGSRRRPRAPRE 2432
+ S G T + +G G+K + + + + S + P+ PR
Sbjct: 1436 SRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPRP 1495
Query: 2433 SAQAIEDLAGFKDPAAGHTEESMTDDKTTKIPCKSSPELEDTATS--SKRRPRTRAQKVE 2490
+++ P++ + + +SS + + A + +R +Q+++
Sbjct: 1496 RSRS---------PSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELD 1546
Query: 2491 VKEELLAVGKLTQTSGETTHTDKEPVGEGKGTKAFKQPAKRKLDAEDVIGSRRQPRAPKE 2550
VK + + E + +D P + K +Q ++ E SR PR +
Sbjct: 1547 VKP--------SASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRS 1598
Query: 2551 KAQPLEDLASFQELSQTPGHTEELANGAADSFTSAPKQTPDSGKPLKISRRVLRAPKVEP 2610
+ P E+ P +G+ S+P+ P + P + RR
Sbjct: 1599 GSSP--------EVKDKPRAAPRAQSGS----DSSPE--PKAPAPRALPRR-------SR 1637
Query: 2611 VGDVVSTRDPVKSQSKSNTSLPPLPFKRGGGKDGSVTGTKRLRCMPAPEEIVEELPASKK 2670
G R P S S S P P K + GS R P P+ K
Sbjct: 1638 SGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGS-------RSSPEPKT---------K 1681
Query: 2671 QRVAPRARGKSSEPVVIMKRSLRTSAKRIEPAEELNSNDMKTNKEEHKLQDSVPENKGIS 2730
R PR R S P + K L ++ + E S ++ + P K S
Sbjct: 1682 SRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRS 1741
Query: 2731 LRSRRQ------NKTEAEQQITEVFVLAERIEINRNEKKPMKTSPEMD----IQNPDDGA 2780
R RR T + + +R+ ++ +T+ D Q+
Sbjct: 1742 SRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRR 1801
Query: 2781 RKPIPRDKVTENKR-----CLRSARQNESSQPKVAEESGGQKSAKVLMQNQKGKGEAGNS 2835
++ R +VT +R RS + ESS+ G ++ + + + S
Sbjct: 1802 QRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSR----TS 1857
Query: 2836 DSMCLRSRKTKSQPAASTLESKSVQRVTRSVKRCAENP---KKAEDNVCVKKIRTRS 2889
+ RSR +++ PA ++R R +P +++ V + R+RS
Sbjct: 1858 PAPWKRSR-SRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRS 1913
Score = 43.9 bits (102), Expect = 0.002
Identities = 247/1307 (18%), Positives = 449/1307 (34%), Gaps = 159/1307 (12%)
Query: 103 QNGRKSTEFPRK----IREQEPARRVSRSSFSSDPDESEGIPLKRRRVSFGGHLRPELFD 158
+ GR + P + R + PARR S + S L RR S H R
Sbjct: 665 RRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRS---HSRTPQRR 721
Query: 159 ENLPPNTPLKRGEAPTKRKSLVMHTPPVLKKIIKEQPQPS-GKQESGSEIHVEVKAQSLV 217
++ K ++R+S +P + K I + S S ++ + ++
Sbjct: 722 GRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRS--- 778
Query: 218 ISPPAPSPRKTPVASDQRRRSCKTAPASSSKSQTEVPKRGGRKSGNLPSKRVSISRSQHD 277
+S +P P++ +R RS + P K+++ P R R S + P K+ S + S
Sbjct: 779 LSGSSPCPKQKSQTPPRRSRSGSSQP----KAKSRTPPRRSRSSSSPPPKQKSKTPS--- 831
Query: 278 ILQMICSKRRSGASEANLIVAKSWADVVKLGAKQTQTKVIKHGPQRSMNKRQRRPATPKK 337
R+S +S S VK G Q + QRR
Sbjct: 832 --------RQSHSSS-------SPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESS 876
Query: 338 PVGEVHSQFSTGHANSPCTIIIGKAHTEKVHVPAR---PYRVLNNFISNQKMDFKEDLS- 393
P E+ S+ + H+ S + K+ T P+R P + IS ++ S
Sbjct: 877 PDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSP 936
Query: 394 GIAEMFKTPVKEQPQLTSTCHIAISNSENLLGKQFQGTDSGE-----EPLLPTSESFGGN 448
+ + + + S C SN E+ L ++ + S +P P +S G+
Sbjct: 937 SPSRVTSRTTPRRSRSVSPC----SNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGS 992
Query: 449 VF-FSAQNAAKQPSDKCSASPPLRRQCIRENGNVAKTPRNTYKMTSLETKTSDTETEPSK 507
+ + A P S S Q ++ V P + +++ T E+
Sbjct: 993 ISPYPKVKAQTPPGPSLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFG- 1051
Query: 508 TVSTANRSGRSTEFRNIQKLPVESKSEETNTEIVECILKRGQKATLLQQRREGEMKEIER 567
VS+ G+S Q P + +S+ ++ E+ + + + Q +G
Sbjct: 1052 -VSSLQLKGQS------QTSP-DHRSDTSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSS 1103
Query: 568 PFETYKENIELKENDEKMKA--MKRSRTWGQKCAPMSDLTDLKSLPDTELMKDTARGQNL 625
P ++++ + A M +S ++ SD + ++ L+ GQ+
Sbjct: 1104 PVTELASRSPIRQDRGEFSASPMLKSGMSPEQSRFQSDSSSYPTVDSNSLL-----GQSR 1158
Query: 626 LQTQDHAKAPKSEKGKITKMPCQSLQPEPINTPTHTKQQLKASLGKVGVKEELLAVGKFT 685
L+T A EK +L P+ T + +Q+ K S V + E V K T
Sbjct: 1159 LET-----AESKEK--------MALPPQEDATASPPRQKDKFSPFPVQDRPESSLVFKDT 1205
Query: 686 RTSGETTHTHREPAGDGKSIRTFKESPKQILDPAARVTGMKKWPRTPKEEAQSLEDLAG- 744
+ RE +G G S T KE + + M+ ++ + Q L L+
Sbjct: 1206 LRTPP-----RERSGAGSSPET-KEQNSALPTSSQDEELMEVVEKSEEPAGQILSHLSSE 1259
Query: 745 FKEL----FQTPGPSEESMTDEKTTKIACKSPPPESVDTPTSTKQWPKRSLRKADVEEEF 800
KE+ F++ EE T + E+V+ P+ W E
Sbjct: 1260 LKEMSTSNFESSPEVEERPAVSLTLDQSQSQASLEAVEVPSMASSWGGPHFSPEHKELSN 1319
Query: 801 LALRKLTPSAGKAMLTPKPAG-----GDEKDIKAFMGTPVQKLDLAGTLPGSKRQLQTPK 855
LR+ + + P G G ++K + P L+ T P + Q+ +
Sbjct: 1320 SPLRENSFGSPLEFRNSGPLGTEMNTGFSSEVKEDLNGPF--LNQLETDPSLDMKEQSTR 1377
Query: 856 EKAQALEDLAGFKELFQTPGHTEELVAAGKTTKIPCDSPQSDPVD-TPTSTKQRPKRSIR 914
+ +L+ P E+ AG ++ SP D V TP+ + S
Sbjct: 1378 SSGHSSSELS--------PDAVEK---AGMSSNQSISSPVLDAVPRTPSRERSSSASSPE 1426
Query: 915 KADVEGELLACRNLMPSAG--------KAMHTPKPSVGEEKDIIIFVGTPVQKLDLTENL 966
D + R+ S+ + H+ S KDI TP + ++
Sbjct: 1427 MKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDI---PRTPSRGRSECDSS 1483
Query: 967 TGSKRRPQTPK-------------------EEAQALEDLTGFKELFQTPGHTEEAVAAGK 1007
K PQTP+ E E K + +TP + +
Sbjct: 1484 PEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQ 1543
Query: 1008 TTKMPCESSPPESADTPTS--TRRQPKTPLEKRDVQKELSALKKLTQTSGETTHTDKVPG 1065
+ +SP E +++ +S ++ + +TPL +R + ++ S + + P
Sbjct: 1544 ELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPE 1603
Query: 1066 GEDKSINAFRETAKQKLDPAASVTGSKRHPKTKEKAQPLEDLAGLKELFQTPVCTDKPTT 1125
+DK A R + P + P+ + E + + +
Sbjct: 1604 VKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPP 1663
Query: 1126 HEKTTKIACRSQPDPVDTPTSSKPQSKRSLRKVDVEEEFFALRKRTPSAGKA-------- 1177
+T + RS P+P S P +RS R L +R+ SA +
Sbjct: 1664 KSRTARRGSRSSPEP--KTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTP 1721
Query: 1178 -MHTPKPAVSGEKNIYAFMGTPVQKLDLTENLTGSKRRLQTPKEKAQALEDLAGFKELFQ 1236
H P+VS + + ++ + + RR ++P K + L + +
Sbjct: 1722 PRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGL-------QRSR 1774
Query: 1237 TRGHTEESMTNDKTAKVACKSSQPDPDKNPASSKRRLKTSLGKVGVKEELLAVGKLTQTS 1296
+R E++ T + + S + S R + G G A + ++TS
Sbjct: 1775 SRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTS 1834
Query: 1297 GETT--HTHTEPTGDGKSMKAFMESP-KQILDSAASLTGSKRQLRTP 1340
+ T PT +S +P K+ A+ T + + RTP
Sbjct: 1835 SRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTP 1881
Score = 43.1 bits (100), Expect = 0.004
Identities = 275/1482 (18%), Positives = 495/1482 (33%), Gaps = 190/1482 (12%)
Query: 106 RKSTEFPRKIREQEPARRVSRSSFSSDPDESEGIPLKRRRVSFGG-----HLRPELFDEN 160
R+S R R + P RR RS P S +RR S H R
Sbjct: 514 RRSRSAQRWGRSRSPQRR-GRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGR 572
Query: 161 LPPNTPLKRGEA----PTKRKSLVMHTPPVLKKIIKEQPQPSGKQESGSEIHVEVKAQSL 216
TP +RG + P +R+S P ++ P G+ S + + +S
Sbjct: 573 SRSRTPARRGRSRSRTPARRRS--RSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRS- 629
Query: 217 VISPPAPSPRKTPVASDQRR--RSCKTAPASSSKSQTEVPKRGGRKSGNLPSKRVSISRS 274
P R++ S RR RS PA +S++ P R GR P++R SRS
Sbjct: 630 ------PVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRS 683
Query: 275 QHDILQMICSKR--RSGASEANLIVAKSWADVVKLGAKQTQTKVIKHGPQRSMNKRQRRP 332
+ + R R G S + +V+ G ++T + G S ++R+ +
Sbjct: 684 RTPARRGRSRSRTPRRGRSRSR--------SLVRRGRSHSRTPQ-RRGRSGSSSERKNKS 734
Query: 333 ATPKKPVGEVHSQFSTGHANSPCTIIIGKAHTEKVHVPARPYRVLNNFISNQK--MDFKE 390
T SQ + +SP +K + +R R L++ S K + +
Sbjct: 735 RT---------SQRRSRSNSSP--------EMKKSRISSRRSRSLSSPRSKAKSRLSLRR 777
Query: 391 DLSGIAEMFKTPVKEQPQLTSTCHIAISNSENLLGKQFQGTDSGEEPLLPTSESFGGNVF 450
LSG +P +Q T +S+ + S P +
Sbjct: 778 SLSG-----SSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQ------- 825
Query: 451 FSAQNAAKQPSDKCSASPPLRRQCIRENGNVAKTPRNTYKMTSLETKTSDTETEP---SK 507
++ ++Q S P ++ G++ N +T ++ +P S+
Sbjct: 826 -KSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSR 884
Query: 508 TVSTANRSGRSTEFRNIQKLPVESKSEETNTEIVECILKRGQKATLLQQRREGEMKEIER 567
T S + SG S P +S S ++ + KA + ++R
Sbjct: 885 TPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQ-------PKVKAIISPRQRSHSGSSSPS 937
Query: 568 PFETYKENIELKENDEKMKAMKRSRTWGQKCAPMSDLTDLKSLPDTELMKDTARGQNLLQ 627
P + + SR + S D K P+T + + G
Sbjct: 938 PSRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETP-PRQSHSGSISPY 996
Query: 628 TQDHAKAPKSEKGKITKMPCQSLQPEPINTPTHTKQQLKASLGK-VGVK------EELLA 680
+ A+ P +K PC P+ + Q SL GVK E
Sbjct: 997 PKVKAQTPPGPSLSGSKSPC----PQE-KSKDSLVQSCPGSLSLCAGVKSSTPPGESYFG 1051
Query: 681 VGKF-TRTSGETTHTHREPAGDGKSIRTFKESPKQILDPAARVTGMKKWPRTPKEEAQSL 739
V + +T+ HR + ++ ESP G + +P E S
Sbjct: 1052 VSSLQLKGQSQTSPDHRSDTSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTELASR 1111
Query: 740 EDLAGFKELFQTPGPSEESMTDEKTTKIACKSPPPESVDTPTSTKQWPKRSLRKADVEEE 799
+ + F + M+ E++ + S P T S + L A+ +E+
Sbjct: 1112 SPIRQDRGEFSASPMLKSGMSPEQSRFQSDSSSYP----TVDSNSLLGQSRLETAESKEK 1167
Query: 800 FLAL-----RKLTPSAGKAMLTPKPAGGDEKDIKAF---MGTPVQKLDLAGTLPGSKRQL 851
+AL +P K +P P + F + TP ++ AG+ P +K Q
Sbjct: 1168 -MALPPQEDATASPPRQKDKFSPFPVQDRPESSLVFKDTLRTPPRERSGAGSSPETKEQN 1226
Query: 852 QTPKEKAQALEDLAGFKELFQTPGHTEELVAAGKTTKIPCDSPQSDPVDTPTSTKQRPKR 911
+Q E+L E + P + + ++ + +S P ++RP
Sbjct: 1227 SALPTSSQD-EELMEVVEKSEEPAGQILSHLSSELKEMSTSNFESSP-----EVEERPAV 1280
Query: 912 SIRKADVEGELLACRNLMPSAGKAMHTPKPSVGEEKDIIIFVGTPVQKLDLTENL----T 967
S+ + + +PS + P S E K++ +P+++ L +
Sbjct: 1281 SLTLDQSQSQASLEAVEVPSMASSWGGPHFS-PEHKEL---SNSPLRENSFGSPLEFRNS 1336
Query: 968 GSKRRPQTPKEEAQALEDLTG-FKELFQTPGHTEEAVAAGKTTKMPCESSPPESADTPTS 1026
G ++ EDL G F +T + + +++ P++ +
Sbjct: 1337 GPLGTEMNTGFSSEVKEDLNGPFLNQLETDPSLDMKEQSTRSSGHSSSELSPDAVEKAGM 1396
Query: 1027 TRRQ----------PKTPLEKRDVQKELSALKK-LTQTSGETTHTDKVPGGEDKSINAFR 1075
+ Q P+TP +R +K L +T + + PG D S R
Sbjct: 1397 SSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTPSRRSRSGSSPGLRDGSGTPSR 1456
Query: 1076 ETAKQKLDPAASVTGSKRHPKTKEKAQPLEDLAGLKELFQTPVCTDKPTTHEKTTKIACR 1135
+ + S G K P+T + G E +P +P +T + R
Sbjct: 1457 HSL------SGSSPGMKDIPRTPSR--------GRSECDSSP----EPKALPQTPRPRSR 1498
Query: 1136 SQPDPVDTPTSSKPQSKRSLRKVDVEEEFFA---LRKRTPSAGKAMHTPKPAVSGEKNIY 1192
S P PQ +RS + V+++ A L +R+ S KP+ S
Sbjct: 1499 SPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSAS------ 1552
Query: 1193 AFMGTPVQKLDLTENLTGSKRRLQTP---KEKAQALEDLAGFKELFQTRGHTEES-MTND 1248
Q+ +++ SK + +TP + ++ + ++ L R + S D
Sbjct: 1553 ------PQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKD 1606
Query: 1249 KTAKVACKSSQPDPDKNPASSKRRLKTSLGKVGVKEELLAVGKLTQTSGETTHTHTEPTG 1308
K S D P + R + G + G + S T + P
Sbjct: 1607 KPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSK--GRGPSPEGSSSTESSPEHPPK 1664
Query: 1309 DGKSMKAFMESPKQILDSAASLTGSKRQLRTP--KGKSEVPEDLAGFIELFQTPSHTKES 1366
+ + SP+ K + RTP + S +L L + S
Sbjct: 1665 SRTARRGSRSSPE-----------PKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSS 1713
Query: 1367 MTNEKTTKVSYRASQPDLVDTPTSSKPQPKRSLRKADTEEEFLAFRKQTPSAGKAMHTPK 1426
T +R S P+ S P+P R + + R +T S +PK
Sbjct: 1714 PETRSRTPPRHRRS-------PSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPK 1766
Query: 1427 P-AVGEEKDINTFLGT-PVQKLDQPGNLPGSNRRLQTRKEKAQALEELTGFRELF-QTPC 1483
P + + + T ++ D+ G+ ++RR Q + +++ G ++P
Sbjct: 1767 PRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPA 1826
Query: 1484 TDNPTTDEKTTKKILCKSPQSDPADTPTNTKQRP-KRSLKKA 1524
+ ++ ++P + + + T P KRS +A
Sbjct: 1827 RQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRA 1868
Score = 42.7 bits (99), Expect = 0.005
Identities = 225/1282 (17%), Positives = 425/1282 (33%), Gaps = 176/1282 (13%)
Query: 1376 SYRASQPDLVDTP---------TSSKPQPKRSLRKADTEEEFLAFRKQTPSAGKAMHTPK 1426
S S P++ D P + S P+PK +A L R ++ S+ K P
Sbjct: 1596 SRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRA------LPRRSRSGSSSKG-RGPS 1648
Query: 1427 PAVGEEKDINTFLGTPVQKLDQPGNL----PGSNRRLQTRKEKAQALEELTGFRELFQTP 1482
P G ++ P + + G+ P + R R+ +++ ELT L +
Sbjct: 1649 PE-GSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRS 1707
Query: 1483 --CTDNPTTDEKTTKKILCKSPQSDPADTPTNTKQRPKRSLKKADVEEEFLAFRKLTPSA 1540
+ +P T +T + S P + R +RS + R +P
Sbjct: 1708 RSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKP 1767
Query: 1541 GKAMHTPKAAVGEEKDINTFVGTPVEKLDLLGNLPGSKRRPQTPKEKAKALEDLAGFKEL 1600
+ + ++ EK T + D G+ + RR Q + +++ G
Sbjct: 1768 -RGLQRSRSRSRREKTRTT------RRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGY 1820
Query: 1601 F-QTPGHTEESMTDDKITEVSCKSPQPDPVKTPTSSKQRLKISLGKVGVKEEVLPVGKLT 1659
++P E S T + ++P PTS K+ + P
Sbjct: 1821 HSRSPARQESSRTSSRRRRGRSRTP-------PTSRKRS----------RSRTSPAPWKR 1863
Query: 1660 QTSGKTTQTHRETAGDGKSIKAFKESAKQMLDPANYGTGMERWPRTPKEEAQSLEDLAGF 1719
S + THR + I + ++ P + R T + ++
Sbjct: 1864 SRSRASPATHRRSRSRTPLIS--RRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRR 1921
Query: 1720 KELFQTPDHTEE-STTDDKTTKIACKSPPPESMDTPTSTRRRPKT---PLGKRDIVEELS 1775
+ +TP T S + TT+ +S TP TRRR ++ P+ +R S
Sbjct: 1922 RSRSRTPPVTRRRSRSRTPTTRRRSRSR------TPPVTRRRSRSRTPPVTRRRSRSRTS 1975
Query: 1776 ALKQLTQTTHTDKVPGDEDKGIN--VFRETAKQKLDPAASVTGSKRQPRTPKGKAQPLED 1833
+ + + T V + V R ++ + P VT + + RTP +
Sbjct: 1976 PITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSP---VTRRRSRSRTPPAIRR---- 2028
Query: 1834 LAGLKELFQTPICTDKPTTHEKTTKIACRSPQPDPVGTPTIFKPQSKRSLRKADVEEESL 1893
+ +TP+ K + I RS P + KRSL ++
Sbjct: 2029 ----RSRSRTPLLPRKRSRSRSPLAIRRRSRSRTPRTA------RGKRSLTRSPP----- 2073
Query: 1894 ALRKRTPSVGKAMDTPKPAGGDEKDMKAFMGTPVQKLDLPGNLPGSK-RWPQTPKEKAQA 1952
A+R+R+ S G + D + A + TP L+ S+ TP ++ ++
Sbjct: 2074 AIRRRSAS-GSSSDRSRSATPPATRNHSGSRTPPVALNSSRMSCFSRPSMSPTPLDRCRS 2132
Query: 1953 LEDLAGFKELFQTPGTDKPTTDEKTTKIACKSPQPDPVDTPASTKQRPKRNLRKADVEEE 2012
PG +P +T + +D P +R + +
Sbjct: 2133 -------------PGMLEPLGSSRTPMSVLQQAGGSMMDGPGPRIPDHQRTSVPENHAQS 2179
Query: 2013 FLALRKRTPSAGKAMDTPKPAVSDEKNINTFVETPVQKLDLLGNLPGSKRQPQTPKEKAE 2072
+AL S G A P + + + V PV + L P + + P A
Sbjct: 2180 RIALALTAISLGTARPPPSMSAAGLAARMSQVPAPVPLMSLR-TAPAANLASRIPAASAA 2238
Query: 2073 ALEDLVGFKELFQTPGHTEESMTDDKITEVSCKSPQPESFKTS--RSSKQRLKIPLVKVD 2130
A+ T + +S T ++ SP+ ++ + + P V +
Sbjct: 2239 AMNLASARTPAIPTAVNLADSRTPAAAAAMNLASPRTAVAPSAVNLADPRTPTAPAVNLA 2298
Query: 2131 MKEEPLAVSKLTRTSGETTQTHTEPTGDSKSIKAFKESPKQILDPAASVTGSRRQLRTRK 2190
P A++ L+ T T T S++ +A S + +A T +R
Sbjct: 2299 GARTPAALAALSLTGSGTPPTAANYPSSSRTPQA-PASANLVGPRSAHATAPVNIAGSRT 2357
Query: 2191 EKARALEDLVDFK--ELFSAPGHTEESMTIDKNTKIPCKSPPPELTDTATSTKRCPKTRP 2248
A A L + S T + + ++ ++ PP L + T ++
Sbjct: 2358 AAALAPASLTSARMAPALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQS 2417
Query: 2249 RKEVKEELSAVERLTQTSGQSTHTHKEPASGDEGIKVLKQRAKKKPNPVEEEPSRRRPRA 2308
R + S R+ Q QS P +++P P A
Sbjct: 2418 RMTSERAPSPSSRMGQAPSQSLLP-----------------------PAQDQPRSPVPSA 2454
Query: 2309 PKEKAQPL----EDLAGFTELSETSGHTQESLTAGKATKIPCESPPL---EVVDTTASTK 2361
++++ L +AG LS + T S + +P + +V + AST
Sbjct: 2455 FSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTG 2514
Query: 2362 RHLRTRVQKVQVKEE----------PSAVKFTQTSGETTDADKEPAGEDKGIK------- 2404
+ + +Q +E S+ + +S ++ + + + +G
Sbjct: 2515 AQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEV 2574
Query: 2405 ALKESAKQTPAPAASVTGSRRRPRAPRESAQAIEDLAGFKDPAAGHTEESMTDDKTTKIP 2464
ALK TPAP +V R P + + + ++ + S + ++
Sbjct: 2575 ALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2634
Query: 2465 CKSSPELEDTATSSKRRPRTRAQKVEVKEELLAVGKLTQTSGETTHTDKEPVGEGKGTKA 2524
SS +++SS + Q + + K P GE + +++
Sbjct: 2635 SSSSSSSSSSSSSSPSPAKPGPQALP----------------KPASPKKPPPGE-RRSRS 2677
Query: 2525 FKQPAKRKLDAEDVIGSRRQPRAPKEKAQPLEDLASFQELSQTPGHTEELANGAADSFTS 2584
++P D+ + S + R P + P + +S E G DS +
Sbjct: 2678 PRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSRRGQ-------RGDSRSP 2730
Query: 2585 APKQTPDSGKPLKISRRVLRAP 2606
+ K+ ++ P + R R+P
Sbjct: 2731 SHKRRRETPSPRPMRHRSSRSP 2752
Score = 40.0 bits (92), Expect = 0.033
Identities = 42/160 (26%), Positives = 66/160 (41%), Gaps = 19/160 (11%)
Query: 122 RRVSRSSFSSDPDESEGIPLKRRRVSFGGHLRPELFDENLPPNTPLK-RGEAPTKRKSLV 180
R SR+S + S P+ RRR PP T + R PT R+
Sbjct: 1899 RSRSRTSVTRRRSRSRASPVSRRRSR-----------SRTPPVTRRRSRSRTPTTRRRSR 1947
Query: 181 MHTPPVLKKIIKEQPQPSGKQESGSEIHVEVKAQSLVISPPAPSPRKTPVAS--DQRRRS 238
TPPV ++ + + P ++ S S + +S + P R S +RR
Sbjct: 1948 SRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSR 2007
Query: 239 CKTAPASSSKSQTEVP----KRGGRKSGNLPSKRVSISRS 274
+T+P + +S++ P +R ++ LP KR S SRS
Sbjct: 2008 SRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKR-SRSRS 2046
Score = 39.7 bits (91), Expect = 0.044
Identities = 45/174 (25%), Positives = 70/174 (40%), Gaps = 27/174 (15%)
Query: 106 RKSTEFPRKIREQEPARRVSRSSFSSDPDESEGIPLKRRRVSFGGHLRPELFDENLPPNT 165
R E R R ++ + +S S +RRR G H R E+ ++
Sbjct: 1776 RSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSS 1835
Query: 166 PLKRGEA---PTKRKSLVMHTPPVLKKIIKEQPQPSGKQESGSEIHVEVKAQSLVISPPA 222
+RG + PT RK T P K + + P+ + S S
Sbjct: 1836 RRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRS----------------- 1878
Query: 223 PSPRKTPVASDQRRRSCKTAPAS--SSKSQTEVPKRGGRKSGNLPSKRVSISRS 274
+TP+ S +R RS +T+P S S+S+T V +R R + S+R S SR+
Sbjct: 1879 ----RTPLISRRRSRS-RTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRT 1927
Score = 35.8 bits (81), Expect = 0.63
Identities = 62/269 (23%), Positives = 107/269 (39%), Gaps = 43/269 (15%)
Query: 96 RYENESLQNGRKSTEFPR---KIREQEPARRV-SRSSFSSDPDESEGIPLKRRRVSFGGH 151
R + S + GR + P + R + PARR SRS + P +RR S
Sbjct: 551 RGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRS---- 606
Query: 152 LRPELFDENLPPNTPLKRGEA----PTKRKSLVMHTPPVLKKIIKEQP-QPSGKQESGSE 206
TP +RG + P +R+S PV ++ P + SG+ S +
Sbjct: 607 ------------RTPARRGRSRSRTPARRRSRTRS--PVRRRSRSRSPARRSGRSRSRTP 652
Query: 207 IHVEVKAQSLVISPPAPSPRKTPVASDQRRRSCKTAPASSSKSQTEVPKRGGRKSGNLPS 266
+++S + S +TP R RS PA +S++ P+RG +S +L
Sbjct: 653 AR-RGRSRSRTPARRGRSRSRTPARRSGRSRS--RTPARRGRSRSRTPRRGRSRSRSLVR 709
Query: 267 KRVSISRSQHDILQMICSKRRSGASEANLIVAKSWADVVKLGAKQTQTKVIKHGPQRSMN 326
+ S SR+ + RSG+S K+ + + ++ + +K R +
Sbjct: 710 RGRSHSRTPQ-------RRGRSGSSSER----KNKSRTSQRRSRSNSSPEMK--KSRISS 756
Query: 327 KRQRRPATPKKPVGEVHSQFSTGHANSPC 355
+R R ++P+ S + +SPC
Sbjct: 757 RRSRSLSSPRSKAKSRLSLRRSLSGSSPC 785
Score = 35.8 bits (81), Expect = 0.63
Identities = 56/233 (24%), Positives = 91/233 (39%), Gaps = 37/233 (15%)
Query: 89 TIIDRSFRYENESLQNGRKSTEFPRKIREQEPARRVSRSSFSSDPDESE-------GIPL 141
+++ R + + GR + RK + + RR SRS+ S + +S +
Sbjct: 706 SLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRR-SRSNSSPEMKKSRISSRRSRSLSS 764
Query: 142 KRRRVSFGGHLRPELFDENLPPN----TPLKRGEAPTKRKSLVMHTPPVLKKIIKEQPQ- 196
R + LR L + P TP +R + + + TPP + P
Sbjct: 765 PRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPK 824
Query: 197 -----PSGKQESGSEIHVEVKAQSLVISPPAPSPRKTPVASDQ----RRRSC-KTAPASS 246
PS + S S H +VK+ +PP +P A++Q +RRSC +++P
Sbjct: 825 QKSKTPSRQSHSSSSPHPKVKSG----TPPRQGSITSPQANEQSVTPQRRSCFESSPDPE 880
Query: 247 SKSQTEVPKRGG--------RKSGNLPSKRVSISRSQHDILQMICSKRRSGAS 291
KS+T P R KS P + S S S ++ I S R+ S
Sbjct: 881 LKSRT--PSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHS 931
Score = 35.4 bits (80), Expect = 0.83
Identities = 61/271 (22%), Positives = 94/271 (34%), Gaps = 39/271 (14%)
Query: 92 DRSFRYENESLQNGRKSTEFPRKIREQEPARRVSRSSFSSDPDESEGI-------PLKRR 144
DRS E L S P + + +R S S S P + G P +
Sbjct: 402 DRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPTSKN 461
Query: 145 RVSFGGHLRPELFDENLPPNTPLKRGEAPTKRKSLVMHTPPVLKKIIKEQPQ---PSGKQ 201
R S G R + R A KR TP PQ Q
Sbjct: 462 R-SHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQ 520
Query: 202 ESGSEIHVEVKAQSLVISPPAP-------SPRKTPVASDQRRRSCKTAPASSSKSQTEVP 254
G + + +S SP P + R+ S +R RS +PA+ +S++ P
Sbjct: 521 RWGRSRSPQRRGRSR--SPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTP 578
Query: 255 KRGGRKSGNLPSKRVSISRSQHDILQMICSKRRSGASEANLIVAKSWADVVKLGAKQTQT 314
R GR P++R S SR+ ++RRS + + G +++T
Sbjct: 579 ARRGRSRSRTPARRRSRSRTP--------TRRRSRSRTP-----------ARRGRSRSRT 619
Query: 315 KVIKHGPQRSMNKRQRRPATPKKPVGEVHSQ 345
+ RS +R+ R +P + G S+
Sbjct: 620 PARRRSRTRSPVRRRSRSRSPARRSGRSRSR 650
Score = 35.4 bits (80), Expect = 0.83
Identities = 33/170 (19%), Positives = 61/170 (35%), Gaps = 19/170 (11%)
Query: 1014 ESSPPESADTPTSTRRQPKTPLEKRDVQKELSALKKLTQTSGETTHTDKVPGGEDKSINA 1073
E PPE PT +R+ ++ S+ + +S ++ + S ++
Sbjct: 2592 EGRPPE----PTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2647
Query: 1074 FRETAKQKLDPAASVTGSKRHP----KTKEKAQPLEDLAGLKELFQTPVCTDKPTTHEKT 1129
AK K+ P +++ +P++ L + L +PV +P+
Sbjct: 2648 SPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSP---- 2703
Query: 1130 TKIACRSQPDPVDTPTSSKPQSKRSLRKVDVEEEFFALRKRTPSAGKAMH 1179
QP P D +SS + R ++ D R+ TPS H
Sbjct: 2704 -------QPSPRDQQSSSSERGSRRGQRGDSRSPSHKRRRETPSPRPMRH 2746
Score = 32.0 bits (71), Expect = 9.1
Identities = 62/274 (22%), Positives = 100/274 (36%), Gaps = 33/274 (12%)
Query: 98 ENESLQNGRKSTEFPRKIREQEPARRVSRSSFSSDPDESEGIPLKRRRVSFGGHLRPELF 157
++ + + G +S+ P+ P RR SRSS P+ + L RR S PE
Sbjct: 1664 KSRTARRGSRSSPEPKTKSRTPPRRRSSRSS----PELTRKARLSRR--SRSASSSPETR 1717
Query: 158 DENLP----------PNTPLKRGEAPTKRKSLVMHTPPVLKKIIKEQPQPSGKQESGSEI 207
P P K + +R + T ++ P+P G Q S S
Sbjct: 1718 SRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRS 1777
Query: 208 HVE----VKAQSLVISPPAPSPRKTPVAS----DQRRRS----CKTAPASSSKSQTEVPK 255
E + + S + S R+ S +RRR +PA S+T +
Sbjct: 1778 RREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRR 1837
Query: 256 RGGRKSGNLPSKRVSISRSQHDILQMICSKRRSGASEANLIVAKSWADVVKLGAKQTQTK 315
R GR S++ S SR+ + RS AS A ++S ++ +++T
Sbjct: 1838 RRGRSRTPPTSRKRSRSRTS----PAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTS 1893
Query: 316 VIKHGPQRSMNK-RQRRPATPKKPVGEVHSQFST 348
+ RS +RR + PV S+ T
Sbjct: 1894 PVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRT 1927
>gi|154146223 splicing factor, arginine/serine-rich 130 [Homo sapiens]
Length = 805
Score = 57.4 bits (137), Expect = 2e-07
Identities = 124/676 (18%), Positives = 241/676 (35%), Gaps = 98/676 (14%)
Query: 2228 SPPPELTDTATSTK---RCPKTRPRKEVKEELSAVERLTQTSGQSTHTHKEPASGDEGIK 2284
+PP + +S + R P P K+ ++ AV+R T PA EG++
Sbjct: 193 APPQNRRERPSSFRDRQRSPIALPVKQEPPQIDAVKRRTL-----------PAWIREGLE 241
Query: 2285 VLKQRAKKKPNPVEEEPSRRRPRAPKEKAQPLEDLAGF------------TELSETSGHT 2332
+++ +KK +E ++R + K++ + ED G ++ E
Sbjct: 242 KMEREKQKKLE--KERMEQQRSQLSKKEKKATEDAEGGDGPRLPQRSKFDSDEEEEDTEN 299
Query: 2333 QESLTAGKATKIPCESPPLEVVDT--TASTKRHLRTRVQKVQVKEEPSAVKFTQTSGETT 2390
E+ ++GK T+ P P E D T K + + K+ + T+ + T
Sbjct: 300 VEAASSGKVTRSPSPVPQEEHSDPEMTEEEKEYQMMLLTKMLL---------TEILLDVT 350
Query: 2391 DADKEPAGEDKGIKALKESAKQTPAPAA--SVTGSRRRPRAPRESAQAIEDLAGFKDPAA 2448
D + +D KA K AKQ +A S+TG L G +
Sbjct: 351 DEEIYYVAKDAHRKATKAPAKQLAQSSALASLTG-----------------LGGLGGYGS 393
Query: 2449 GHTEESMTDDKTTKIPCKSSPELEDTATSSKRRPRTRAQKVEVKEELLAVGKLTQTSGET 2508
G +E+ +D + S + +D + R + A + KE+ L K + +
Sbjct: 394 GDSEDERSDRGS------ESSDTDDEELRHRIRQKQEAFWRKEKEQQLLHDKQMEEEKQQ 447
Query: 2509 THTDKEPVGE--GKGTKAFKQPAKRKLDAEDVIGSRRQPRAPKEKAQPLEDLASFQELSQ 2566
T + + E K + R+ D + V +R P +P ++ ++ +
Sbjct: 448 TERVTKEMNEFIHKEQNSLSLLEAREADGDVVNEKKRTPNETTSVLEPKKEHKEKEKQGR 507
Query: 2567 TPGHTEELANGAADSFTSAPKQTPDSGKPLKISRRVLRAPKVEPVGDVVSTRDPVKSQSK 2626
+ + + +++S TS+ T S S + + + P + +
Sbjct: 508 SRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSR---------SSSPKRKKRH 558
Query: 2627 SNTSLPPLPFKRGGGKDGS-----VTGTKRLRCMPAPEEIVEELPASKKQRVAPRARGKS 2681
S + P + +R + S + R++ + +++ +P +
Sbjct: 559 SRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERERRRNRSPSRERRR 618
Query: 2682 SEPVVIMKRSLRTSAKRIEPAEELNSNDMKTNKEEHKLQDSVPENKGISLRSRRQNKTEA 2741
S +R+ R S R +++ + HK + E + RSR +K
Sbjct: 619 SRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKERSRSIDKDRK 678
Query: 2742 EQQITEVFVLAERIEINRNEKKPMKTSPEMDIQNPDDGARKPIPRDKVTENKRCLRSARQ 2801
++ +R E + E+K K S + D++ + R+ +
Sbjct: 679 KKDKEREREQDKRKEKQKREEKDFKFSSQ---------------DDRLKRKRESERTFSR 723
Query: 2802 NESSQPKVAEESGGQKSAKVLMQNQK---GKGEAGNSDSMCLRSRKTKSQPAASTLESKS 2858
+ S K+ Q S K ++ K G +G S S S K K S+S
Sbjct: 724 SGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESPGSSKEKKAKKPKHSRSRS 783
Query: 2859 VQRVTRSVKRCAENPK 2874
V++ RS K+ + K
Sbjct: 784 VEKSQRSGKKASRKHK 799
>gi|154146193 splicing factor, arginine/serine-rich 130 [Homo sapiens]
Length = 805
Score = 57.4 bits (137), Expect = 2e-07
Identities = 124/676 (18%), Positives = 241/676 (35%), Gaps = 98/676 (14%)
Query: 2228 SPPPELTDTATSTK---RCPKTRPRKEVKEELSAVERLTQTSGQSTHTHKEPASGDEGIK 2284
+PP + +S + R P P K+ ++ AV+R T PA EG++
Sbjct: 193 APPQNRRERPSSFRDRQRSPIALPVKQEPPQIDAVKRRTL-----------PAWIREGLE 241
Query: 2285 VLKQRAKKKPNPVEEEPSRRRPRAPKEKAQPLEDLAGF------------TELSETSGHT 2332
+++ +KK +E ++R + K++ + ED G ++ E
Sbjct: 242 KMEREKQKKLE--KERMEQQRSQLSKKEKKATEDAEGGDGPRLPQRSKFDSDEEEEDTEN 299
Query: 2333 QESLTAGKATKIPCESPPLEVVDT--TASTKRHLRTRVQKVQVKEEPSAVKFTQTSGETT 2390
E+ ++GK T+ P P E D T K + + K+ + T+ + T
Sbjct: 300 VEAASSGKVTRSPSPVPQEEHSDPEMTEEEKEYQMMLLTKMLL---------TEILLDVT 350
Query: 2391 DADKEPAGEDKGIKALKESAKQTPAPAA--SVTGSRRRPRAPRESAQAIEDLAGFKDPAA 2448
D + +D KA K AKQ +A S+TG L G +
Sbjct: 351 DEEIYYVAKDAHRKATKAPAKQLAQSSALASLTG-----------------LGGLGGYGS 393
Query: 2449 GHTEESMTDDKTTKIPCKSSPELEDTATSSKRRPRTRAQKVEVKEELLAVGKLTQTSGET 2508
G +E+ +D + S + +D + R + A + KE+ L K + +
Sbjct: 394 GDSEDERSDRGS------ESSDTDDEELRHRIRQKQEAFWRKEKEQQLLHDKQMEEEKQQ 447
Query: 2509 THTDKEPVGE--GKGTKAFKQPAKRKLDAEDVIGSRRQPRAPKEKAQPLEDLASFQELSQ 2566
T + + E K + R+ D + V +R P +P ++ ++ +
Sbjct: 448 TERVTKEMNEFIHKEQNSLSLLEAREADGDVVNEKKRTPNETTSVLEPKKEHKEKEKQGR 507
Query: 2567 TPGHTEELANGAADSFTSAPKQTPDSGKPLKISRRVLRAPKVEPVGDVVSTRDPVKSQSK 2626
+ + + +++S TS+ T S S + + + P + +
Sbjct: 508 SRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSR---------SSSPKRKKRH 558
Query: 2627 SNTSLPPLPFKRGGGKDGS-----VTGTKRLRCMPAPEEIVEELPASKKQRVAPRARGKS 2681
S + P + +R + S + R++ + +++ +P +
Sbjct: 559 SRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERERRRNRSPSRERRR 618
Query: 2682 SEPVVIMKRSLRTSAKRIEPAEELNSNDMKTNKEEHKLQDSVPENKGISLRSRRQNKTEA 2741
S +R+ R S R +++ + HK + E + RSR +K
Sbjct: 619 SRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKERSRSIDKDRK 678
Query: 2742 EQQITEVFVLAERIEINRNEKKPMKTSPEMDIQNPDDGARKPIPRDKVTENKRCLRSARQ 2801
++ +R E + E+K K S + D++ + R+ +
Sbjct: 679 KKDKEREREQDKRKEKQKREEKDFKFSSQ---------------DDRLKRKRESERTFSR 723
Query: 2802 NESSQPKVAEESGGQKSAKVLMQNQK---GKGEAGNSDSMCLRSRKTKSQPAASTLESKS 2858
+ S K+ Q S K ++ K G +G S S S K K S+S
Sbjct: 724 SGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESPGSSKEKKAKKPKHSRSRS 783
Query: 2859 VQRVTRSVKRCAENPK 2874
V++ RS K+ + K
Sbjct: 784 VEKSQRSGKKASRKHK 799
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 56.6 bits (135), Expect = 3e-07
Identities = 124/683 (18%), Positives = 258/683 (37%), Gaps = 102/683 (14%)
Query: 2113 KTSRSSKQRLKIPLVKVDMKEEPL----------AVSKLTRTSGETTQTHTEPTGDSKSI 2162
+ +R ++R + ++ +EE L A + + +TT T+T+ GD ++
Sbjct: 36 EAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEA- 94
Query: 2163 KAFKESPKQILDPAASVTGSRRQLRTRKEKARALEDLVDFKELF-----SAPGH-----T 2212
AF E +RR+ R +K ALE +F S P T
Sbjct: 95 -AFLERL------------ARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDT 141
Query: 2213 EESMTIDKNTKIPCKSPPPELTDTATSTKRCPKTRPRKEVKEELSAVERLTQTSGQSTHT 2272
E+ T +K K + E+ +T T TK K R A E + +
Sbjct: 142 AENETTEKEEKSESRQERYEIEETETVTKSYQKNDWR-------DAEENKKEDKEKEEEE 194
Query: 2273 HKEPASGDEGIKVLKQRAKKKPNPVEEEP----------SRRRPRAPKEKAQPLEDLAGF 2322
++P G G ++ ++K +EE S P+ +E+ Q ++++
Sbjct: 195 EEKPKRGSIGENQVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQEEEREQGSDEISHH 254
Query: 2323 TELSETS------------GHTQESLTAGKATKIPCESPPLEVVDTTASTKRHLRTRVQK 2370
++ E +E + A + KI E +E + A+ +R R ++
Sbjct: 255 EKMEEEDKERAEAERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQERERREAEER 314
Query: 2371 VQVKEEPSAVKFTQTSGETTDADKEPAGEDKGIKALKESAKQTPAPAASVTGSRRRPRAP 2430
+++EE K + +++ A E++ + +KE K+ + +R
Sbjct: 315 ERMREEE---KRAAEERQRIKEEEKRAAEER--QRIKEEEKRAAEERQRIKEEEKRAAEE 369
Query: 2431 RESAQAIEDLAGFKDPAAGHTEESMTDDKTTKIPCKSSPELEDTATSSKRRPRTRAQKVE 2490
R+ A+A E+ E++ +++ K + +LE+ + + + + +KVE
Sbjct: 370 RQRARAEEE------------EKAKVEEQ------KRNKQLEEKK-HAMQETKIKGEKVE 410
Query: 2491 VKEELLAVGKLTQTSGETTHTDKEPVGEGKGTKAFKQPAKRKLDAEDVIGSRRQPRAPKE 2550
K E V + + + GE KGTK + K + D + K+
Sbjct: 411 QKIEGKWVNEKKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKK 470
Query: 2551 KAQPLEDLASFQELSQTPGHTEELANGAADSFTSAPKQTPDS-----GKPLKISRRVLRA 2605
+P E++ SF + + G TE + + T K T ++ G+ ++ A
Sbjct: 471 DKEPKEEVKSFMDRKK--GFTEVKSQNG-EFMTHKLKHTENTFSRPGGRASVDTKEAEGA 527
Query: 2606 PKVEPVGDVVSTRDPVKSQSKSNTSLPPLPFKRGGGKDGSVTGTKRLRCMPAPEEIVEEL 2665
P+VE + R + + T + ++ ++ + + +++EE
Sbjct: 528 PQVEAGKRLEELR-----RRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEE 582
Query: 2666 PASKKQRVAPRARGKSSEPVVIMKRSLRTSAKRIEPAEELNSNDMKTNKEEHKLQDSVPE 2725
+KQ A R + E + + R A+ E +++ + + +K+ K P+
Sbjct: 583 EQRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEKRQKMPEDGLSDDKKPFKC--FTPK 640
Query: 2726 NKGISLRSRRQNKTEAEQQITEV 2748
+ + R + ++ Q+ + V
Sbjct: 641 GSSLKIEERAEFLNKSVQKSSGV 663
Score = 43.5 bits (101), Expect = 0.003
Identities = 142/690 (20%), Positives = 251/690 (36%), Gaps = 113/690 (16%)
Query: 2005 RKADVEEEFLALRKRTPSAGKAMD----TPKPAVSDEKNINTFVETPVQKLDLLGNLPG- 2059
R+ +E L ++ S G+ D + +V DE+ T T V+ D L
Sbjct: 41 RRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERL 100
Query: 2060 SKRQPQTPKEKAEALEDLVGFKELF----------QTPGHTEESMTDDKI---------- 2099
++R+ + K EALE F + T E+ T +K
Sbjct: 101 ARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERY 160
Query: 2100 ----TEVSCKSPQPESFKTSRSSKQRLKIPLVKVDMKEE---------PLAVSKLTRTSG 2146
TE KS Q ++ + +K+ K + + K + + V + T S
Sbjct: 161 EIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQVEVMVEEKTTESQ 220
Query: 2147 ETTQTHTEPTGDSKSIKAFKESPKQILDPAASVTGSRRQLRTRKEKARALEDLVDFKELF 2206
E T + G S + +E ++ + ++ + KE+A A ++ +E
Sbjct: 221 EETVVMSLKNGQISSEEPKQEEERE--QGSDEISHHEKMEEEDKERAEAERARLEAEE-- 276
Query: 2207 SAPGHTEESMTIDKNTKIPCKSPPPELTDTATSTKRCPKTRPRKEVKEELSAVE-RLTQT 2265
E + +++ KI + E + A + +R R E +E + E R +
Sbjct: 277 ------RERIKAEQDKKIADERARIEAEEKAAAQER---ERREAEERERMREEEKRAAEE 327
Query: 2266 SGQSTHTHKEPASGDEGIKVLKQRAKKKPNPVEEEPSR-----RRPRAPKEKAQPLEDLA 2320
+ K A + IK ++RA ++ ++EE R +R RA +E+ +E+
Sbjct: 328 RQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQK 387
Query: 2321 GFTELSETSGHTQESLTAGKAT------KIPCESPPLEVVDTTASTKRHLRTRVQKVQVK 2374
+L E QE+ G+ K E E TA K+ + KVQ K
Sbjct: 388 RNKQLEEKKHAMQETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLKKQGEEKGTKVQAK 447
Query: 2375 -----EEPSAVKFTQTSGETTDADKEPAGE-------DKGIKALK--------------E 2408
E+ K + E DKEP E KG +K E
Sbjct: 448 REKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTE 507
Query: 2409 SAKQTPAPAASVTGSRRRPRAPRESAQAIEDLAGFKDPAAGHTEESMTDDKTTKIPCKSS 2468
+ P ASV E+ + +E+L + G T ES +K + +++
Sbjct: 508 NTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRR----GET-ESEEFEKLKQKQQEAA 562
Query: 2469 PELEDTATSSKRRPRTRAQKVEVKEELLAVGKLTQTSGETTHTDKEPVGEGKGTKAFKQP 2528
ELE+ + R + ++ + +++ A KL + +K + E + +
Sbjct: 563 LELEELKKKREERRKVLEEEEQRRKQEEADRKLRE------EEEKRRLKEEIERRRAEAA 616
Query: 2529 AKRKLDAEDVIGSRRQP---RAPKEKAQPLEDLASFQELSQTPGHTEELANGAA------ 2579
KR+ ED + ++P PK + +E+ A F S + + AA
Sbjct: 617 EKRQKMPEDGLSDDKKPFKCFTPKGSSLKIEERAEFLNKSVQKSSGVKSTHQAAIVSKID 676
Query: 2580 ---DSFTSAPKQTPDSGKPLKISRRVLRAP 2606
+ +TSA + T S KP K + L P
Sbjct: 677 SRLEQYTSAIEGT-KSAKPTKPAASDLPVP 705
Score = 38.9 bits (89), Expect = 0.075
Identities = 112/596 (18%), Positives = 216/596 (36%), Gaps = 93/596 (15%)
Query: 2358 ASTKRHLRTRVQKVQVKEEPSAVKFTQTSGETTDADKEPAGEDKGIKALKESAKQTPAPA 2417
A+ +R R R ++++ K+E ++ G+ TD + A + K + T
Sbjct: 37 AARERRRRARQERLRQKQEEESL------GQVTDQVEVNAQNSVPDEEAKTTTTNTQVEG 90
Query: 2418 ASVTG-----SRRRPRAPRESAQAIEDLAGFKDPAAGHTEESMTDDKTTKIPCK--SSPE 2470
+RR R + +A+E F DP D + +P + +
Sbjct: 91 DDEAAFLERLARREERRQKRLQEALERQKEF-DPTI--------TDASLSLPSRRMQNDT 141
Query: 2471 LEDTATSSKRRPRTRAQKVEVKEELLAVGKLTQTSGETTHTDKEPVGEGKGTKAFKQPAK 2530
E+ T + + +R ++ E+ EE V K Q + + + + K + ++P +
Sbjct: 142 AENETTEKEEKSESRQERYEI-EETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKR 200
Query: 2531 RKLDAEDVIGSRRQPRAPKEKAQPLEDLASFQELSQTPGHTEELANGAADSFTSAPKQTP 2590
+ V + ++ + L + Q S+ P EE G+ D + K
Sbjct: 201 GSIGENQVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQEEEREQGS-DEISHHEKMEE 259
Query: 2591 DSGKPLKISRRVLRAP-----KVEPVGDVVSTRDPVKSQSKSNTSLPPLPFKRGGGKDGS 2645
+ + + R L A K E + R ++++ K+ +R ++
Sbjct: 260 EDKERAEAERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQ----ERERREAEERE 315
Query: 2646 VTGTKRLRCMPAPEEIVEE--LPASKKQRVAPRARGKSSEPVVIMKRSLRTSAKR----I 2699
+ R + I EE A ++QR+ + + E I + R + +R
Sbjct: 316 RMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARA 375
Query: 2700 EPAEELNSNDMKTNKE---------------------------------EHKLQDSV--- 2723
E E+ + K NK+ E KLQ +V
Sbjct: 376 EEEEKAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLKK 435
Query: 2724 -PENKGISLRSRRQNKTEAEQQITEVFVLAERIEINRNEKKPMKT-------SPEMDIQN 2775
E KG ++++R+ E + + + E+I+ ++ K+ +K+ E+ QN
Sbjct: 436 QGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQN 495
Query: 2776 PDDGARKPIPRDKVTENKRCLRSARQNESSQPKVAEESGGQKSAKVLMQNQKGKGEAGNS 2835
+ K K TEN R S K AE + ++ K L + ++ +GE +
Sbjct: 496 GEFMTHKL----KHTENTFSRPGGR--ASVDTKEAEGAPQVEAGKRLEELRRRRGE---T 546
Query: 2836 DSMCLRSRKTKSQPAASTLESKSVQRVTRSVKRCAENPKKAEDNVCVKKIRTRSHR 2891
+S K K Q AA LE +R R K E ++ + +K+R +
Sbjct: 547 ESEEFEKLKQKQQEAALELEELKKKREERR-KVLEEEEQRRKQEEADRKLREEEEK 601
Score = 35.8 bits (81), Expect = 0.63
Identities = 52/235 (22%), Positives = 93/235 (39%), Gaps = 35/235 (14%)
Query: 1261 DPDKNPASSKRRLKT------------SLGKVGVKEELLAVGKLTQTSGETTHTHTEPTG 1308
D D+ A+ +RR + SLG+V + E+ A + +TT T+T+ G
Sbjct: 31 DDDEEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQVEG 90
Query: 1309 DGKSMKAFMESPKQILDSAASLTGSKRQLRTPKGKSEVPE------DLAGFIELFQTPSH 1362
D ++ AF+E + +RQ R + E D + + + +
Sbjct: 91 DDEA--AFLE--------RLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQND 140
Query: 1363 TKESMTNEKTTKVSYRASQPDLVDTPTSSKPQPKRSLRKAD----TEEEFLAFRKQTPSA 1418
T E+ T EK K R + ++ +T T +K K R A+ ++E ++ P
Sbjct: 141 TAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKR 200
Query: 1419 GKAMHTPKPAVGEEKDINTFLGTPVQKLDQPGNLPGSNRRLQTRKEKAQALEELT 1473
G + EEK + T V L N S+ + +E+ Q +E++
Sbjct: 201 GSIGENQVEVMVEEKTTESQEETVVMSLK---NGQISSEEPKQEEEREQGSDEIS 252
Score = 34.7 bits (78), Expect = 1.4
Identities = 90/420 (21%), Positives = 159/420 (37%), Gaps = 49/420 (11%)
Query: 1000 EEAVAAGKTTKMPCESSPPESADTPTSTRRQPKTPLEKRDVQKELSALKKLTQTSGETTH 1059
EE AA + + E + + + + E++ +E +K+ + + E
Sbjct: 298 EEKAAAQERERREAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQ 357
Query: 1060 TDKVPGGEDKSINAFRETAKQKLDPAASVTGSKRHPKTKEKAQPLED--LAGLK------ 1111
K E+K R+ A+ + + A V KR+ + +EK +++ + G K
Sbjct: 358 RIKE---EEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQKIE 414
Query: 1112 -----------ELFQTPVCTDKPTTHEKTTKIACRSQPDPVDTPTSSKPQSKRSLRKVDV 1160
+ QT V K EK TK+ + + D PT K + K K D
Sbjct: 415 GKWVNEKKAQEDKLQTAVL--KKQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDK 472
Query: 1161 E--EEFFALRKRTPSAGKAMHTPKPAVSGEKNIYAFMGTPVQKLDLTENLTGSKRRLQTP 1218
E EE + R K T + +GE FM ++ + T + G + + T
Sbjct: 473 EPKEEVKSFMDR-----KKGFTEVKSQNGE-----FMTHKLKHTENTFSRPGGRASVDTK 522
Query: 1219 K-EKAQALEDLAGFKELFQTRGHTEESMTNDKTAKVACKSSQPDPDKNPASSKRRLKTSL 1277
+ E A +E +EL + RG TE K + + + K +R++
Sbjct: 523 EAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEE 582
Query: 1278 GKVGVKEELLAVGKLTQTSGETTHTHTEPTGDGKSMKAFMESPKQILDSAASLTGSKRQL 1337
+ +EE A KL + E + + + +A + K D L+ K+
Sbjct: 583 EQRRKQEE--ADRKLRE---EEEKRRLKEEIERRRAEAAEKRQKMPED---GLSDDKKPF 634
Query: 1338 R--TPKGKSEVPEDLAGFI-ELFQTPSHTKESMTNEKTTKVSYRASQ-PDLVDTPTSSKP 1393
+ TPKG S E+ A F+ + Q S K + +K+ R Q ++ S+KP
Sbjct: 635 KCFTPKGSSLKIEERAEFLNKSVQKSSGVKSTHQAAIVSKIDSRLEQYTSAIEGTKSAKP 694
Score = 34.3 bits (77), Expect = 1.8
Identities = 85/453 (18%), Positives = 165/453 (36%), Gaps = 43/453 (9%)
Query: 2472 EDTATSSKRRPRTRAQKVEVKEELLAVGKLTQTSGETTHTDKEPVGEGKGTKAFKQPAKR 2531
++ + +RR R R +++ K+E ++G++T E + P E K T Q
Sbjct: 33 DEEEAARERRRRARQERLRQKQEEESLGQVTD-QVEVNAQNSVPDEEAKTTTTNTQ---- 87
Query: 2532 KLDAEDVIG-----SRRQPRAPKEKAQPLEDLASFQEL---SQTPGHTEELANGAADSFT 2583
++ +D +RR+ R K + LE F + + + N A++ T
Sbjct: 88 -VEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENET 146
Query: 2584 SAPKQTPDSGK---PLKISRRVLRAPKVEPVGDVVSTRDPVKSQSKSNTSLPPLPFKRGG 2640
+ ++ +S + ++ + V ++ + D + K + + P KRG
Sbjct: 147 TEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKP----KRGS 202
Query: 2641 GKDGSVTGTKRLRCMPAPEEIV----EELPASKKQRVAPRARGKSSEPVVIMKRSLRTSA 2696
+ V + + EE V + S ++ R + S+ + ++
Sbjct: 203 IGENQVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKMEEEDK 262
Query: 2697 KRIE------PAEELNSNDMKTNKE--EHKLQDSVPENKGISLRSRRQNKTEAEQQITEV 2748
+R E AEE + +K+ + + + E R RR+ + + E
Sbjct: 263 ERAEAERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQERERREAEERERMREEEK 322
Query: 2749 FVLAERIEINRNEKKPMKTSPEMDIQNPDDGARKPIPRDKVTENKRC--LRSARQNESSQ 2806
ER I EK+ I+ + A + R K E + + AR E +
Sbjct: 323 RAAEERQRIKEEEKR--AAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEK 380
Query: 2807 PKVAEESGGQ--KSAKVLMQNQKGKGEAGNS--DSMCLRSRKTKSQPAASTLESKSVQRV 2862
KV E+ + + K MQ K KGE + + +K + + + K Q
Sbjct: 381 AKVEEQKRNKQLEEKKHAMQETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLKK--QGE 438
Query: 2863 TRSVKRCAENPKKAEDNVCVKKIRTRSHRDSED 2895
+ K A+ K ED KK + + +D
Sbjct: 439 EKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKD 471
>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
[Homo sapiens]
Length = 914
Score = 56.2 bits (134), Expect = 5e-07
Identities = 151/719 (21%), Positives = 255/719 (35%), Gaps = 106/719 (14%)
Query: 1745 SPPPESMDTPTS----TRRRPKTPLGKRDIVEELSALKQLTQTTHTDKVPGDEDKGINVF 1800
SP P S PTS T TP + + E + L T K +G+
Sbjct: 197 SPTPASATAPTSQGIPTSDEESTPKKSKARILESITVSSLMATPQDPK-----GQGVGTG 251
Query: 1801 RETAKQKLDPAASVTGSKRQPRTPKGKAQPLEDLAGLKELFQTPICTDKPTTHEKTTKIA 1860
R +K ++ A G + P P + L + F TP + + + + IA
Sbjct: 252 RSASKLRI--AQVSPGPRDSPAFPDSPWRERVLAPILPDNFSTPTGSRTDSQSVRHSPIA 309
Query: 1861 CRSPQPDPVGTP--TIFKPQS-----KRSLRKADVEEESLALRKRTPSVGKAM---DTPK 1910
SP P + + K +S R L K EE + + R S + + + P+
Sbjct: 310 PSSPSPQVLAQKYSLVAKQESVVRRASRRLAKKTAEEPAASGRIICHSYLERLLNVEVPQ 369
Query: 1911 PAGGDEKDMKAFMGTPVQKLD--LPGNLPGSKRWPQTPKEKAQALEDLAGFKELFQTPGT 1968
G ++K+ PV + +P N G+ WP E A + TP
Sbjct: 370 KVGSEQKEPPE-EAEPVAAAEPEVPEN-NGNNSWPHNDTEIANS------------TPNP 415
Query: 1969 DKPTTDEKTTKIACKSPQPDPVDTPASTKQ--RPKRNLRKADVE---EEFLALRKRTPSA 2023
+ +T + + D D P Q R KR+ ++A E E+ L + P
Sbjct: 416 KPAASSPETPSAGQQEAKTDQADGPREPPQSARRKRSYKQAVSELDEEQHLEDEELQPPR 475
Query: 2024 GKAMDTPKPAVSDEKNINTFVETPVQKLDLLGNLPGSKRQ------------PQTPKEK- 2070
K +P PA + + TF+ T VQ+ +L + R PKEK
Sbjct: 476 SKTPSSPCPASKVVRPLRTFLHT-VQRNQMLMTPTSAPRSVMKSFIKRNTPLRMDPKEKE 534
Query: 2071 AEALEDLVGFKELFQTPGHTEESMTDDKITEVSCKSPQPESFKTSRSSKQRLKIPLVKVD 2130
+ LE+L +E Q E ++ EV K + E + +++R++
Sbjct: 535 RQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLK--REERLRKVLQARERVE------Q 586
Query: 2131 MKEE--PLAVSKLTRTSGETTQTHTEPTGDSKSIKAFKESPKQILDPAASVTGSRRQLRT 2188
MKEE K + +T + E + K+ K K + K++ + A R
Sbjct: 587 MKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKK--KAAAKKMEEVEAR--------RK 636
Query: 2189 RKEKARALEDLVDFKELFSAPGHTEESMTIDKNTKIPCKSPPPELTDTATSTKRCPKTRP 2248
++E+AR L L EE + K E A KR + R
Sbjct: 637 QEEEARRLRWL-----------QQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQRE 685
Query: 2249 RKEVKEELSAVERLTQTSGQSTHTHKEPASGDEGIKVLKQRAKKKPNPVEEEPSRR---- 2304
++ ++E ER Q + +E ++ + ++R + + E E + R
Sbjct: 686 QERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKE 745
Query: 2305 ---RPRAPKEKAQPLEDLAGFTELSETSGHTQESLTAGKATKIPCESPPLEVVDTTASTK 2361
R K+K + + LA E +E+ A KA + + V + A T
Sbjct: 746 QLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAAGASKALNVTVD------VQSPACTS 799
Query: 2362 RHLRTRVQKVQVKEEPSAVKFTQTSGETTDADKEPAGEDKGIKALKESAKQTPAPAASV 2420
+ + + K P S ++TD + P K + A+ TP A +
Sbjct: 800 YQMTPQGHRAPPKINPDNYGMDLNSDDSTDDEAHPR------KPIPTWARGTPLSQAII 852
Score = 36.2 bits (82), Expect = 0.48
Identities = 60/262 (22%), Positives = 99/262 (37%), Gaps = 50/262 (19%)
Query: 648 QSLQPEPINTPTHTKQQLKASLGKVGVKEELLAVGKFTRTSGETTHTHREPAGDGK---- 703
QS++ PI P+ Q+ A + K+E + R + +T EPA G+
Sbjct: 301 QSVRHSPI-APSSPSPQVLAQKYSLVAKQESVVRRASRRLAKKTAE---EPAASGRIICH 356
Query: 704 -------------SIRTFKESPKQILDPAARV-------TGMKKWPRTPKEEAQSLEDLA 743
+ + ++ P + +P A G WP E A S +
Sbjct: 357 SYLERLLNVEVPQKVGSEQKEPPEEAEPVAAAEPEVPENNGNNSWPHNDTEIANSTPNPK 416
Query: 744 GFKELFQTPGPSEESMTDEKTTKIACKSPPPESVDTPTSTKQWPKRSLRKADVEEEFLAL 803
+TP ++ + KT + PP+S S KQ ++ + D EE+ L
Sbjct: 417 PAASSPETPSAGQQ---EAKTDQADGPREPPQSARRKRSYKQ----AVSELD-EEQHLED 468
Query: 804 RKLTPSAGKAMLTPKPAGGDEKDIKAFMGTPVQKLDLAGTLPGSKRQL------------ 851
+L P K +P PA + ++ F+ T VQ+ + T + R +
Sbjct: 469 EELQPPRSKTPSSPCPASKVVRPLRTFLHT-VQRNQMLMTPTSAPRSVMKSFIKRNTPLR 527
Query: 852 QTPKEK-AQALEDLAGFKELFQ 872
PKEK Q LE+L +E Q
Sbjct: 528 MDPKEKERQRLENLRRKEEAEQ 549
>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
sapiens]
Length = 699
Score = 54.7 bits (130), Expect = 1e-06
Identities = 108/546 (19%), Positives = 203/546 (37%), Gaps = 86/546 (15%)
Query: 2249 RKEVKEELSAVERLTQTSGQSTHTHKEPASGDEGIKVLKQRAKKKPNPVEEEPSRRRPRA 2308
+K VK + A + +S+ + + +S DE K K K PV + + P
Sbjct: 147 QKGVKPQAKAA-KAPPKKAKSSDSDSDSSSEDEPPK----NQKPKITPVTVKAQTKAPPK 201
Query: 2309 PKEKAQPLED-LAGFTELSETSGHTQESLTAGKATKIPCESPPLEVVDTTASTKRHLRTR 2367
P A + + A + S +S + + KA P ++ P + V
Sbjct: 202 PARAAPKIANGKAASSSSSSSSSSSSDDSEEEKAAATPKKTVPKKQV------------- 248
Query: 2368 VQKVQVKEEPSAVKFTQTSGETTDADKEPAGEDKGIKALKESAKQTPAPAASVTGSRRRP 2427
V K VK + + + +S +++ ++E K+ K P P +SV
Sbjct: 249 VAKAPVKAATTPTRKSSSSEDSSSDEEEEQ---------KKPMKNKPGPYSSV------- 292
Query: 2428 RAPRESAQAIEDLAGFKDPAAGHTEESMTDDKTTKIPCKSSPELEDTATSSKRRPRTRAQ 2487
P SA + G + P ++ + + S + D+++ +++P T+A
Sbjct: 293 --PPPSAPPPKKSLGTQPPKKAVEKQQPVESS------EDSSDESDSSSEEEKKPPTKAV 344
Query: 2488 KVEVKEELLAVGKLTQTSGETTHTDKEPVGEGKGTKAFKQPAKRKLDAEDVIGSRRQPRA 2547
+ + K ++S +++ +D E A +PA ++ + + A
Sbjct: 345 VSKATTKPPPAKKAAESSSDSSDSDSSEDDE-----APSKPAGTTKNSSNKPAVTTKSPA 399
Query: 2548 PKEKAQPLEDLASFQELSQTPGHTEELANGAADSFTSAPKQTPDSGKPLKISRRVLRAP- 2606
K A P + + Q+L + ++ S K+ + KP ++ L P
Sbjct: 400 VKPAAAPKQPVGGGQKLLTRKADSSSSEEESSSSEEEKTKKMVATTKPKATAKAALSLPA 459
Query: 2607 KVEPVGDVVSTRDPVKSQSK------SNTSLPPLPFKRGGG---------KDGSVTGTKR 2651
K P G S+ D S S+ S +++ P K GG K G +
Sbjct: 460 KQAPQGSRDSSSDSDSSSSEEEEEKTSKSAVKKKPQKVAGGAAPSKPASAKKGKAESSNS 519
Query: 2652 LRCMPAPEEIVEELPASKKQRV-APRARGKSSEPVVIMKRSLRTSAKRIEPAEELNSNDM 2710
+ EE E+L R AP+A G S+ + K + +EE
Sbjct: 520 SSSDDSSEEEEEKLKGKGSPRPQAPKANGTSALTA--------QNGKAAKNSEE------ 565
Query: 2711 KTNKEEHKLQDSVPENKGISLRSRRQNKTEAEQQITEVFVLAERIEINRNEKKPMKTSPE 2770
+EE K + +V +K SL+ R+QN+ E + + A++I++ P + E
Sbjct: 566 ---EEEEKKKAAVVVSKSGSLKKRKQNEAAKEAETPQ----AKKIKLQTPNTFPKRKKGE 618
Query: 2771 MDIQNP 2776
+P
Sbjct: 619 KRASSP 624
Score = 40.4 bits (93), Expect = 0.026
Identities = 97/497 (19%), Positives = 167/497 (33%), Gaps = 68/497 (13%)
Query: 699 AGDGKSIRTFKESPKQILDPAARVTGMKKWPRTPKEEAQSLEDLAGFKELFQTPGPSEES 758
+ D S + ++ P + P +K + P + A++ +A K + S S
Sbjct: 166 SSDSDSDSSSEDEPPKNQKPKITPVTVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSS 225
Query: 759 MTDEKTTKIACKSP-------------PPESVDTPTSTKQWPKRSLRKADVEEEFLALRK 805
+D+ + A +P P ++ TPT + S +D EEE K
Sbjct: 226 SSDDSEEEKAAATPKKTVPKKQVVAKAPVKAATTPTRKSSSSEDS--SSDEEEEQKKPMK 283
Query: 806 LTPSAGKAMLTPKPAGGDEKDIKAFMGTPVQKLDLAGTLPGSKRQLQTPKEKAQALEDLA 865
P G P P+ P K L P + Q P E ++ D +
Sbjct: 284 NKP--GPYSSVPPPSA------------PPPKKSLGTQPPKKAVEKQQPVESSEDSSDES 329
Query: 866 GFKELFQTPGHTEELVAAGKTTKIPCDSPQSDPVDTPTSTKQRPKRSIRKADVEGELLAC 925
+ T+ +V+ T P D+ S + K
Sbjct: 330 DSSSEEEKKPPTKAVVSKATTKPPPAKKAAESSSDSSDSDSSEDDEAPSK---------- 379
Query: 926 RNLMPSAGKAMHTPKPSVGEEKDIIIFVGTPVQKLDLTENLTGSKRRPQTPKEEAQALED 985
P+ + KP+V + + P Q + + L K + +EE+ + E+
Sbjct: 380 ----PAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKLLTRKADSSSSEEESSSSEE 435
Query: 986 LTGFKELFQTPGHTEEAVAAGKTTKMPCESSPPESADTPTSTRRQPKTPLEKRDVQKELS 1045
K++ T T+ A +P + +P S D S+ + E+ + + S
Sbjct: 436 -EKTKKMVAT---TKPKATAKAALSLPAKQAPQGSRD---SSSDSDSSSSEEEEEKTSKS 488
Query: 1046 ALKKLTQTSGETTHTDKVPGGEDKSINAFRETAKQKLDPAASVTGSKRHPKTKEKAQPLE 1105
A+KK Q KV GG S + A K A S S ++E+ + L+
Sbjct: 489 AVKKKPQ---------KVAGGAAPS-----KPASAKKGKAESSNSSSSDDSSEEEEEKLK 534
Query: 1106 DLAGLKELFQTPVCTDKPTTHEKTTKIACRSQPDPVDTPTSSKPQSKRSLRKVDVEEEFF 1165
+ Q P + K A S+ + + ++ SK K + E
Sbjct: 535 GKGSPRP--QAPKANGTSALTAQNGKAAKNSEEEEEEKKKAAVVVSKSGSLKKRKQNE-A 591
Query: 1166 ALRKRTPSAGK-AMHTP 1181
A TP A K + TP
Sbjct: 592 AKEAETPQAKKIKLQTP 608
Score = 33.5 bits (75), Expect = 3.1
Identities = 44/195 (22%), Positives = 74/195 (37%), Gaps = 37/195 (18%)
Query: 107 KSTEFP-RKIREQEP-ARRVSRSSFSSDPDES-------EGIPLKRRRV----------- 146
KS + P RK++ P A++ + + SSD ++S +G P K+ V
Sbjct: 59 KSAKVPERKLQANGPVAKKAKKKASSSDSEDSSEEEEEVQGPPAKKAAVPAKRVGLPPGK 118
Query: 147 -------SFGGHLRPELFDENLPPNTPLKRGEAPTKRKSLVMHTPPVLKKIIKEQPQPSG 199
S + DE P+++G P + + PP K S
Sbjct: 119 AAAKASESSSSEESSDDDDEEDQKKQPVQKGVKPQAKAA---KAPPKKAKSSDSDSDSSS 175
Query: 200 KQESGSE-----IHVEVKAQSLVISPPAPSPRKTPVASDQRRRSCKTAPASSSKSQTEVP 254
+ E V VKAQ+ +PP P+ +A+ + S ++ +SSS +E
Sbjct: 176 EDEPPKNQKPKITPVTVKAQTK--APPKPARAAPKIANGKAASSSSSSSSSSSSDDSEEE 233
Query: 255 KRGGRKSGNLPSKRV 269
K +P K+V
Sbjct: 234 KAAATPKKTVPKKQV 248
Score = 32.3 bits (72), Expect = 7.0
Identities = 73/368 (19%), Positives = 129/368 (35%), Gaps = 59/368 (16%)
Query: 2523 KAFKQPAKRKLDAEDVIGSRRQPRAPKEKAQPLEDLASFQELSQTP------------GH 2570
K+ K P +RKL A + + + +A + ED + +E Q P G
Sbjct: 59 KSAKVP-ERKLQANGPVAKKAKKKASSSDS---EDSSEEEEEVQGPPAKKAAVPAKRVGL 114
Query: 2571 TEELANGAADSFTSAPKQTPDSGKPLKISRRVLRAPKVEPVGDVVSTRDPVKSQSKSNTS 2630
A A +S+ + + D + + + V + K + + S S S++S
Sbjct: 115 PPGKAAAKASESSSSEESSDDDDEEDQKKQPVQKGVKPQAKAAKAPPKKAKSSDSDSDSS 174
Query: 2631 LPPLPFKRGGGKDGSVTGTKRLRCMPAPEEIVEELPASKKQRVAPR-ARGKSSEPVVIMK 2689
P K K VT + + P P R AP+ A GK++
Sbjct: 175 SEDEPPKNQKPKITPVTVKAQTKAPPKPA------------RAAPKIANGKAASS----S 218
Query: 2690 RSLRTSAKRIEPAEELNSNDMKTNKEEHKLQDSVPENKGISLRSRRQNKTEAEQQITEVF 2749
S +S+ + EE + K + ++ P K + +R+ + +E E
Sbjct: 219 SSSSSSSSSDDSEEEKAAATPKKTVPKKQVVAKAPV-KAATTPTRKSSSSEDSSSDEE-- 275
Query: 2750 VLAERIEINRNEKKPMKTSPEMDIQNPDDGARKP------IPRDKVTENKRCLRSARQNE 2803
+KKPMK P P A P P K E ++ + S+ +
Sbjct: 276 ---------EEQKKPMKNKPGPYSSVPPPSAPPPKKSLGTQPPKKAVEKQQPVESSEDSS 326
Query: 2804 SSQPKVAEESGGQKSAKVLMQ--------NQKGKGEAGNSDSMCLRSRKTKSQPAASTLE 2855
+EE + V+ + + + + +SDS + S+PA +T
Sbjct: 327 DESDSSSEEEKKPPTKAVVSKATTKPPPAKKAAESSSDSSDSDSSEDDEAPSKPAGTTKN 386
Query: 2856 SKSVQRVT 2863
S + VT
Sbjct: 387 SSNKPAVT 394
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.308 0.125 0.350
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 127,073,573
Number of Sequences: 37866
Number of extensions: 6864839
Number of successful extensions: 26802
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 27
Number of HSP's successfully gapped in prelim test: 590
Number of HSP's that attempted gapping in prelim test: 21065
Number of HSP's gapped (non-prelim): 4798
length of query: 2896
length of database: 18,247,518
effective HSP length: 120
effective length of query: 2776
effective length of database: 13,703,598
effective search space: 38041188048
effective search space used: 38041188048
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 71 (32.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.