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Search of human proteins with 224994221
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|224994221 SH3-domain binding protein 2 isoform b [Homo
sapiens]
(618 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|224994221 SH3-domain binding protein 2 isoform b [Homo sapiens] 1300 0.0
gi|224994219 SH3-domain binding protein 2 isoform c [Homo sapiens] 1186 0.0
gi|170014705 SH3-domain binding protein 2 isoform a [Homo sapiens] 1176 0.0
gi|170014703 SH3-domain binding protein 2 isoform a [Homo sapiens] 1176 0.0
gi|68161504 Wiskott-Aldrich syndrome protein family member 1 [Ho... 67 6e-11
gi|68161502 Wiskott-Aldrich syndrome protein family member 1 [Ho... 67 6e-11
gi|68161500 Wiskott-Aldrich syndrome protein family member 1 [Ho... 67 6e-11
gi|4507913 Wiskott-Aldrich syndrome protein family member 1 [Hom... 67 6e-11
gi|163965366 nascent polypeptide-associated complex alpha subuni... 64 3e-10
gi|221139926 NHS-like 1 [Homo sapiens] 63 7e-10
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 63 7e-10
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa... 63 7e-10
gi|149773456 hypothetical protein LOC643314 [Homo sapiens] 63 9e-10
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 60 5e-09
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 60 8e-09
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo... 60 8e-09
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ... 60 8e-09
gi|41281612 zinc finger protein 828 [Homo sapiens] 60 8e-09
gi|56549666 tyrosine kinase, non-receptor, 2 isoform 1 [Homo sap... 59 1e-08
gi|58331191 tyrosine kinase, non-receptor, 2 isoform 2 [Homo sap... 59 1e-08
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin... 59 1e-08
gi|110349719 titin isoform N2-A [Homo sapiens] 58 2e-08
gi|122937496 WAS/WASL interacting protein family, member 3 [Homo... 58 3e-08
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] 58 3e-08
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] 58 3e-08
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] 58 3e-08
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 57 4e-08
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 57 4e-08
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 57 4e-08
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 57 4e-08
>gi|224994221 SH3-domain binding protein 2 isoform b [Homo sapiens]
Length = 618
Score = 1300 bits (3365), Expect = 0.0
Identities = 618/618 (100%), Positives = 618/618 (100%)
Query: 1 MAGSGPRPRSWGRREAGARDEAAAAGGRGPGPCRCSQGRRAWIAPGKPAMPAAWTPFMAA 60
MAGSGPRPRSWGRREAGARDEAAAAGGRGPGPCRCSQGRRAWIAPGKPAMPAAWTPFMAA
Sbjct: 1 MAGSGPRPRSWGRREAGARDEAAAAGGRGPGPCRCSQGRRAWIAPGKPAMPAAWTPFMAA 60
Query: 61 EEMHWPVPMKAIGAQNLLTMPGGVAKAGYLHKKGGTQLQLLKWPLRFVIIHKRCVYYFKS 120
EEMHWPVPMKAIGAQNLLTMPGGVAKAGYLHKKGGTQLQLLKWPLRFVIIHKRCVYYFKS
Sbjct: 61 EEMHWPVPMKAIGAQNLLTMPGGVAKAGYLHKKGGTQLQLLKWPLRFVIIHKRCVYYFKS 120
Query: 121 STSASPQGAFSLSGYNRVMRAAEETTSNNVFPFKIIHISKKHRTWFFSASSEEERKSWMA 180
STSASPQGAFSLSGYNRVMRAAEETTSNNVFPFKIIHISKKHRTWFFSASSEEERKSWMA
Sbjct: 121 STSASPQGAFSLSGYNRVMRAAEETTSNNVFPFKIIHISKKHRTWFFSASSEEERKSWMA 180
Query: 181 LLRREIGHFHEKKDLPLDTSDSSSDTDSFYGAVERPVDISLSPYPTDNEDYEHDDEDDSY 240
LLRREIGHFHEKKDLPLDTSDSSSDTDSFYGAVERPVDISLSPYPTDNEDYEHDDEDDSY
Sbjct: 181 LLRREIGHFHEKKDLPLDTSDSSSDTDSFYGAVERPVDISLSPYPTDNEDYEHDDEDDSY 240
Query: 241 LEPDSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPPKHG 300
LEPDSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPPKHG
Sbjct: 241 LEPDSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPPKHG 300
Query: 301 LPDVGLAAEDSKRDPLCPRRAEPCPRVPATPRRMSDPPLSTMPTAPGLRKPPCFRESASP 360
LPDVGLAAEDSKRDPLCPRRAEPCPRVPATPRRMSDPPLSTMPTAPGLRKPPCFRESASP
Sbjct: 301 LPDVGLAAEDSKRDPLCPRRAEPCPRVPATPRRMSDPPLSTMPTAPGLRKPPCFRESASP 360
Query: 361 SPEPWTPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSEPPPVPANKPKFLKIA 420
SPEPWTPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSEPPPVPANKPKFLKIA
Sbjct: 361 SPEPWTPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSEPPPVPANKPKFLKIA 420
Query: 421 EEDPPREAAMPGLFVPPVAPRPPALKLPVPEAMARPAVLPRPEKPQLPHLQRSPPDGQSF 480
EEDPPREAAMPGLFVPPVAPRPPALKLPVPEAMARPAVLPRPEKPQLPHLQRSPPDGQSF
Sbjct: 421 EEDPPREAAMPGLFVPPVAPRPPALKLPVPEAMARPAVLPRPEKPQLPHLQRSPPDGQSF 480
Query: 481 RSFSFEKPRQPSQADTGGDDSDEDYEKVPLPNSVFVNTTESCEVERLFKATSPRGEPQDG 540
RSFSFEKPRQPSQADTGGDDSDEDYEKVPLPNSVFVNTTESCEVERLFKATSPRGEPQDG
Sbjct: 481 RSFSFEKPRQPSQADTGGDDSDEDYEKVPLPNSVFVNTTESCEVERLFKATSPRGEPQDG 540
Query: 541 LYCIRNSSTKSGKVLVVWDETSNKVRNYRIFEKDSKFYLEGEVLFVSVGSMVEHYHTHVL 600
LYCIRNSSTKSGKVLVVWDETSNKVRNYRIFEKDSKFYLEGEVLFVSVGSMVEHYHTHVL
Sbjct: 541 LYCIRNSSTKSGKVLVVWDETSNKVRNYRIFEKDSKFYLEGEVLFVSVGSMVEHYHTHVL 600
Query: 601 PSHQSLLLRHPYGYTGPR 618
PSHQSLLLRHPYGYTGPR
Sbjct: 601 PSHQSLLLRHPYGYTGPR 618
>gi|224994219 SH3-domain binding protein 2 isoform c [Homo sapiens]
Length = 589
Score = 1186 bits (3069), Expect = 0.0
Identities = 574/598 (95%), Positives = 578/598 (96%), Gaps = 12/598 (2%)
Query: 23 AAAGGRGPGPCRCSQGRRA--WIAPGKPAMPAAWTPFMAAEEMHWPVPMKAIGAQNLLTM 80
A+ G R P P R S+GRRA W++ FMAAEEMHWPVPMKAIGAQNLLTM
Sbjct: 2 ASLGPRTPAPSR-SRGRRAMCWVST---------ISFMAAEEMHWPVPMKAIGAQNLLTM 51
Query: 81 PGGVAKAGYLHKKGGTQLQLLKWPLRFVIIHKRCVYYFKSSTSASPQGAFSLSGYNRVMR 140
PGGVAKAGYLHKKGGTQLQLLKWPLRFVIIHKRCVYYFKSSTSASPQGAFSLSGYNRVMR
Sbjct: 52 PGGVAKAGYLHKKGGTQLQLLKWPLRFVIIHKRCVYYFKSSTSASPQGAFSLSGYNRVMR 111
Query: 141 AAEETTSNNVFPFKIIHISKKHRTWFFSASSEEERKSWMALLRREIGHFHEKKDLPLDTS 200
AAEETTSNNVFPFKIIHISKKHRTWFFSASSEEERKSWMALLRREIGHFHEKKDLPLDTS
Sbjct: 112 AAEETTSNNVFPFKIIHISKKHRTWFFSASSEEERKSWMALLRREIGHFHEKKDLPLDTS 171
Query: 201 DSSSDTDSFYGAVERPVDISLSPYPTDNEDYEHDDEDDSYLEPDSPEPGRLEDALMHPPA 260
DSSSDTDSFYGAVERPVDISLSPYPTDNEDYEHDDEDDSYLEPDSPEPGRLEDALMHPPA
Sbjct: 172 DSSSDTDSFYGAVERPVDISLSPYPTDNEDYEHDDEDDSYLEPDSPEPGRLEDALMHPPA 231
Query: 261 YPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPPKHGLPDVGLAAEDSKRDPLCPRR 320
YPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPPKHGLPDVGLAAEDSKRDPLCPRR
Sbjct: 232 YPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPPKHGLPDVGLAAEDSKRDPLCPRR 291
Query: 321 AEPCPRVPATPRRMSDPPLSTMPTAPGLRKPPCFRESASPSPEPWTPGHGACSTSSAAIM 380
AEPCPRVPATPRRMSDPPLSTMPTAPGLRKPPCFRESASPSPEPWTPGHGACSTSSAAIM
Sbjct: 292 AEPCPRVPATPRRMSDPPLSTMPTAPGLRKPPCFRESASPSPEPWTPGHGACSTSSAAIM 351
Query: 381 ATATSRNCDKLKSFHLSPRGPPTSEPPPVPANKPKFLKIAEEDPPREAAMPGLFVPPVAP 440
ATATSRNCDKLKSFHLSPRGPPTSEPPPVPANKPKFLKIAEEDPPREAAMPGLFVPPVAP
Sbjct: 352 ATATSRNCDKLKSFHLSPRGPPTSEPPPVPANKPKFLKIAEEDPPREAAMPGLFVPPVAP 411
Query: 441 RPPALKLPVPEAMARPAVLPRPEKPQLPHLQRSPPDGQSFRSFSFEKPRQPSQADTGGDD 500
RPPALKLPVPEAMARPAVLPRPEKPQLPHLQRSPPDGQSFRSFSFEKPRQPSQADTGGDD
Sbjct: 412 RPPALKLPVPEAMARPAVLPRPEKPQLPHLQRSPPDGQSFRSFSFEKPRQPSQADTGGDD 471
Query: 501 SDEDYEKVPLPNSVFVNTTESCEVERLFKATSPRGEPQDGLYCIRNSSTKSGKVLVVWDE 560
SDEDYEKVPLPNSVFVNTTESCEVERLFKATSPRGEPQDGLYCIRNSSTKSGKVLVVWDE
Sbjct: 472 SDEDYEKVPLPNSVFVNTTESCEVERLFKATSPRGEPQDGLYCIRNSSTKSGKVLVVWDE 531
Query: 561 TSNKVRNYRIFEKDSKFYLEGEVLFVSVGSMVEHYHTHVLPSHQSLLLRHPYGYTGPR 618
TSNKVRNYRIFEKDSKFYLEGEVLFVSVGSMVEHYHTHVLPSHQSLLLRHPYGYTGPR
Sbjct: 532 TSNKVRNYRIFEKDSKFYLEGEVLFVSVGSMVEHYHTHVLPSHQSLLLRHPYGYTGPR 589
>gi|170014705 SH3-domain binding protein 2 isoform a [Homo sapiens]
Length = 561
Score = 1176 bits (3042), Expect = 0.0
Identities = 561/561 (100%), Positives = 561/561 (100%)
Query: 58 MAAEEMHWPVPMKAIGAQNLLTMPGGVAKAGYLHKKGGTQLQLLKWPLRFVIIHKRCVYY 117
MAAEEMHWPVPMKAIGAQNLLTMPGGVAKAGYLHKKGGTQLQLLKWPLRFVIIHKRCVYY
Sbjct: 1 MAAEEMHWPVPMKAIGAQNLLTMPGGVAKAGYLHKKGGTQLQLLKWPLRFVIIHKRCVYY 60
Query: 118 FKSSTSASPQGAFSLSGYNRVMRAAEETTSNNVFPFKIIHISKKHRTWFFSASSEEERKS 177
FKSSTSASPQGAFSLSGYNRVMRAAEETTSNNVFPFKIIHISKKHRTWFFSASSEEERKS
Sbjct: 61 FKSSTSASPQGAFSLSGYNRVMRAAEETTSNNVFPFKIIHISKKHRTWFFSASSEEERKS 120
Query: 178 WMALLRREIGHFHEKKDLPLDTSDSSSDTDSFYGAVERPVDISLSPYPTDNEDYEHDDED 237
WMALLRREIGHFHEKKDLPLDTSDSSSDTDSFYGAVERPVDISLSPYPTDNEDYEHDDED
Sbjct: 121 WMALLRREIGHFHEKKDLPLDTSDSSSDTDSFYGAVERPVDISLSPYPTDNEDYEHDDED 180
Query: 238 DSYLEPDSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPP 297
DSYLEPDSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPP
Sbjct: 181 DSYLEPDSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPP 240
Query: 298 KHGLPDVGLAAEDSKRDPLCPRRAEPCPRVPATPRRMSDPPLSTMPTAPGLRKPPCFRES 357
KHGLPDVGLAAEDSKRDPLCPRRAEPCPRVPATPRRMSDPPLSTMPTAPGLRKPPCFRES
Sbjct: 241 KHGLPDVGLAAEDSKRDPLCPRRAEPCPRVPATPRRMSDPPLSTMPTAPGLRKPPCFRES 300
Query: 358 ASPSPEPWTPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSEPPPVPANKPKFL 417
ASPSPEPWTPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSEPPPVPANKPKFL
Sbjct: 301 ASPSPEPWTPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSEPPPVPANKPKFL 360
Query: 418 KIAEEDPPREAAMPGLFVPPVAPRPPALKLPVPEAMARPAVLPRPEKPQLPHLQRSPPDG 477
KIAEEDPPREAAMPGLFVPPVAPRPPALKLPVPEAMARPAVLPRPEKPQLPHLQRSPPDG
Sbjct: 361 KIAEEDPPREAAMPGLFVPPVAPRPPALKLPVPEAMARPAVLPRPEKPQLPHLQRSPPDG 420
Query: 478 QSFRSFSFEKPRQPSQADTGGDDSDEDYEKVPLPNSVFVNTTESCEVERLFKATSPRGEP 537
QSFRSFSFEKPRQPSQADTGGDDSDEDYEKVPLPNSVFVNTTESCEVERLFKATSPRGEP
Sbjct: 421 QSFRSFSFEKPRQPSQADTGGDDSDEDYEKVPLPNSVFVNTTESCEVERLFKATSPRGEP 480
Query: 538 QDGLYCIRNSSTKSGKVLVVWDETSNKVRNYRIFEKDSKFYLEGEVLFVSVGSMVEHYHT 597
QDGLYCIRNSSTKSGKVLVVWDETSNKVRNYRIFEKDSKFYLEGEVLFVSVGSMVEHYHT
Sbjct: 481 QDGLYCIRNSSTKSGKVLVVWDETSNKVRNYRIFEKDSKFYLEGEVLFVSVGSMVEHYHT 540
Query: 598 HVLPSHQSLLLRHPYGYTGPR 618
HVLPSHQSLLLRHPYGYTGPR
Sbjct: 541 HVLPSHQSLLLRHPYGYTGPR 561
>gi|170014703 SH3-domain binding protein 2 isoform a [Homo sapiens]
Length = 561
Score = 1176 bits (3042), Expect = 0.0
Identities = 561/561 (100%), Positives = 561/561 (100%)
Query: 58 MAAEEMHWPVPMKAIGAQNLLTMPGGVAKAGYLHKKGGTQLQLLKWPLRFVIIHKRCVYY 117
MAAEEMHWPVPMKAIGAQNLLTMPGGVAKAGYLHKKGGTQLQLLKWPLRFVIIHKRCVYY
Sbjct: 1 MAAEEMHWPVPMKAIGAQNLLTMPGGVAKAGYLHKKGGTQLQLLKWPLRFVIIHKRCVYY 60
Query: 118 FKSSTSASPQGAFSLSGYNRVMRAAEETTSNNVFPFKIIHISKKHRTWFFSASSEEERKS 177
FKSSTSASPQGAFSLSGYNRVMRAAEETTSNNVFPFKIIHISKKHRTWFFSASSEEERKS
Sbjct: 61 FKSSTSASPQGAFSLSGYNRVMRAAEETTSNNVFPFKIIHISKKHRTWFFSASSEEERKS 120
Query: 178 WMALLRREIGHFHEKKDLPLDTSDSSSDTDSFYGAVERPVDISLSPYPTDNEDYEHDDED 237
WMALLRREIGHFHEKKDLPLDTSDSSSDTDSFYGAVERPVDISLSPYPTDNEDYEHDDED
Sbjct: 121 WMALLRREIGHFHEKKDLPLDTSDSSSDTDSFYGAVERPVDISLSPYPTDNEDYEHDDED 180
Query: 238 DSYLEPDSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPP 297
DSYLEPDSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPP
Sbjct: 181 DSYLEPDSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPP 240
Query: 298 KHGLPDVGLAAEDSKRDPLCPRRAEPCPRVPATPRRMSDPPLSTMPTAPGLRKPPCFRES 357
KHGLPDVGLAAEDSKRDPLCPRRAEPCPRVPATPRRMSDPPLSTMPTAPGLRKPPCFRES
Sbjct: 241 KHGLPDVGLAAEDSKRDPLCPRRAEPCPRVPATPRRMSDPPLSTMPTAPGLRKPPCFRES 300
Query: 358 ASPSPEPWTPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSEPPPVPANKPKFL 417
ASPSPEPWTPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSEPPPVPANKPKFL
Sbjct: 301 ASPSPEPWTPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSEPPPVPANKPKFL 360
Query: 418 KIAEEDPPREAAMPGLFVPPVAPRPPALKLPVPEAMARPAVLPRPEKPQLPHLQRSPPDG 477
KIAEEDPPREAAMPGLFVPPVAPRPPALKLPVPEAMARPAVLPRPEKPQLPHLQRSPPDG
Sbjct: 361 KIAEEDPPREAAMPGLFVPPVAPRPPALKLPVPEAMARPAVLPRPEKPQLPHLQRSPPDG 420
Query: 478 QSFRSFSFEKPRQPSQADTGGDDSDEDYEKVPLPNSVFVNTTESCEVERLFKATSPRGEP 537
QSFRSFSFEKPRQPSQADTGGDDSDEDYEKVPLPNSVFVNTTESCEVERLFKATSPRGEP
Sbjct: 421 QSFRSFSFEKPRQPSQADTGGDDSDEDYEKVPLPNSVFVNTTESCEVERLFKATSPRGEP 480
Query: 538 QDGLYCIRNSSTKSGKVLVVWDETSNKVRNYRIFEKDSKFYLEGEVLFVSVGSMVEHYHT 597
QDGLYCIRNSSTKSGKVLVVWDETSNKVRNYRIFEKDSKFYLEGEVLFVSVGSMVEHYHT
Sbjct: 481 QDGLYCIRNSSTKSGKVLVVWDETSNKVRNYRIFEKDSKFYLEGEVLFVSVGSMVEHYHT 540
Query: 598 HVLPSHQSLLLRHPYGYTGPR 618
HVLPSHQSLLLRHPYGYTGPR
Sbjct: 541 HVLPSHQSLLLRHPYGYTGPR 561
>gi|68161504 Wiskott-Aldrich syndrome protein family member 1 [Homo
sapiens]
Length = 559
Score = 66.6 bits (161), Expect = 6e-11
Identities = 63/226 (27%), Positives = 80/226 (35%), Gaps = 49/226 (21%)
Query: 243 PDSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPPKHGLP 302
P SP GR + P PPPP+P+ A S S TS P P+ PPPPP
Sbjct: 308 PQSPATGRTPVFVSPTPPPPPPPLPS----ALSTSSLRASMTSTPPPPVPPPPPP----- 358
Query: 303 DVGLAAEDSKRDPLCPRRAEPCPRVPATPRRMSDPPLSTMPTAPGL---RKPPCFRESAS 359
P A P VP PP + + APG+ PP
Sbjct: 359 ---------------PATALQAPAVP--------PPPAPLQIAPGVLHPAPPPIAPPLVQ 395
Query: 360 PSPEPWTPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSEPPP-VPANKPKFLK 418
PSP P C T + + L P PP PPP + + P +
Sbjct: 396 PSP-PVARAAPVCETVPVHPLPQGEVQG--------LPPPPPPPPLPPPGIRPSSPVTVT 446
Query: 419 IAEEDP----PREAAMPGLFVPPVAPRPPALKLPVPEAMARPAVLP 460
P P + PG VP + P PP+ +P E P+ LP
Sbjct: 447 ALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQVIPASEPKRHPSTLP 492
Score = 51.2 bits (121), Expect = 3e-06
Identities = 54/191 (28%), Positives = 66/191 (34%), Gaps = 46/191 (24%)
Query: 293 PPPPPKHGLPDVGLAAEDSKRDPLCPRRAEPCPRVPATPRRMSDPPLSTMPTAPGLRKPP 352
PPPPP HG A D+K P C A + P +P + P
Sbjct: 279 PPPPPMHG-------AGDAKPIPTCISSATGL--------------IENRPQSPATGRTP 317
Query: 353 CFRESASPSPEPWTPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSEPPPVPAN 412
F P P P P A STSS T+T PP PPP PA
Sbjct: 318 VFVSPTPPPPPPPLPS--ALSTSSLRASMTSTPP--------------PPVPPPPPPPAT 361
Query: 413 KPKFLKIAEEDPPREAAMPGLFVPPVAP-RPPALKLPVPEAMARPAV-------LPRPEK 464
+ + P + A PG+ P P PP ++ P A A P LP+ E
Sbjct: 362 ALQAPAVPPPPAPLQIA-PGVLHPAPPPIAPPLVQPSPPVARAAPVCETVPVHPLPQGEV 420
Query: 465 PQLPHLQRSPP 475
LP PP
Sbjct: 421 QGLPPPPPPPP 431
>gi|68161502 Wiskott-Aldrich syndrome protein family member 1 [Homo
sapiens]
Length = 559
Score = 66.6 bits (161), Expect = 6e-11
Identities = 63/226 (27%), Positives = 80/226 (35%), Gaps = 49/226 (21%)
Query: 243 PDSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPPKHGLP 302
P SP GR + P PPPP+P+ A S S TS P P+ PPPPP
Sbjct: 308 PQSPATGRTPVFVSPTPPPPPPPLPS----ALSTSSLRASMTSTPPPPVPPPPPP----- 358
Query: 303 DVGLAAEDSKRDPLCPRRAEPCPRVPATPRRMSDPPLSTMPTAPGL---RKPPCFRESAS 359
P A P VP PP + + APG+ PP
Sbjct: 359 ---------------PATALQAPAVP--------PPPAPLQIAPGVLHPAPPPIAPPLVQ 395
Query: 360 PSPEPWTPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSEPPP-VPANKPKFLK 418
PSP P C T + + L P PP PPP + + P +
Sbjct: 396 PSP-PVARAAPVCETVPVHPLPQGEVQG--------LPPPPPPPPLPPPGIRPSSPVTVT 446
Query: 419 IAEEDP----PREAAMPGLFVPPVAPRPPALKLPVPEAMARPAVLP 460
P P + PG VP + P PP+ +P E P+ LP
Sbjct: 447 ALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQVIPASEPKRHPSTLP 492
Score = 51.2 bits (121), Expect = 3e-06
Identities = 54/191 (28%), Positives = 66/191 (34%), Gaps = 46/191 (24%)
Query: 293 PPPPPKHGLPDVGLAAEDSKRDPLCPRRAEPCPRVPATPRRMSDPPLSTMPTAPGLRKPP 352
PPPPP HG A D+K P C A + P +P + P
Sbjct: 279 PPPPPMHG-------AGDAKPIPTCISSATGL--------------IENRPQSPATGRTP 317
Query: 353 CFRESASPSPEPWTPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSEPPPVPAN 412
F P P P P A STSS T+T PP PPP PA
Sbjct: 318 VFVSPTPPPPPPPLPS--ALSTSSLRASMTSTPP--------------PPVPPPPPPPAT 361
Query: 413 KPKFLKIAEEDPPREAAMPGLFVPPVAP-RPPALKLPVPEAMARPAV-------LPRPEK 464
+ + P + A PG+ P P PP ++ P A A P LP+ E
Sbjct: 362 ALQAPAVPPPPAPLQIA-PGVLHPAPPPIAPPLVQPSPPVARAAPVCETVPVHPLPQGEV 420
Query: 465 PQLPHLQRSPP 475
LP PP
Sbjct: 421 QGLPPPPPPPP 431
>gi|68161500 Wiskott-Aldrich syndrome protein family member 1 [Homo
sapiens]
Length = 559
Score = 66.6 bits (161), Expect = 6e-11
Identities = 63/226 (27%), Positives = 80/226 (35%), Gaps = 49/226 (21%)
Query: 243 PDSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPPKHGLP 302
P SP GR + P PPPP+P+ A S S TS P P+ PPPPP
Sbjct: 308 PQSPATGRTPVFVSPTPPPPPPPLPS----ALSTSSLRASMTSTPPPPVPPPPPP----- 358
Query: 303 DVGLAAEDSKRDPLCPRRAEPCPRVPATPRRMSDPPLSTMPTAPGL---RKPPCFRESAS 359
P A P VP PP + + APG+ PP
Sbjct: 359 ---------------PATALQAPAVP--------PPPAPLQIAPGVLHPAPPPIAPPLVQ 395
Query: 360 PSPEPWTPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSEPPP-VPANKPKFLK 418
PSP P C T + + L P PP PPP + + P +
Sbjct: 396 PSP-PVARAAPVCETVPVHPLPQGEVQG--------LPPPPPPPPLPPPGIRPSSPVTVT 446
Query: 419 IAEEDP----PREAAMPGLFVPPVAPRPPALKLPVPEAMARPAVLP 460
P P + PG VP + P PP+ +P E P+ LP
Sbjct: 447 ALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQVIPASEPKRHPSTLP 492
Score = 51.2 bits (121), Expect = 3e-06
Identities = 54/191 (28%), Positives = 66/191 (34%), Gaps = 46/191 (24%)
Query: 293 PPPPPKHGLPDVGLAAEDSKRDPLCPRRAEPCPRVPATPRRMSDPPLSTMPTAPGLRKPP 352
PPPPP HG A D+K P C A + P +P + P
Sbjct: 279 PPPPPMHG-------AGDAKPIPTCISSATGL--------------IENRPQSPATGRTP 317
Query: 353 CFRESASPSPEPWTPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSEPPPVPAN 412
F P P P P A STSS T+T PP PPP PA
Sbjct: 318 VFVSPTPPPPPPPLPS--ALSTSSLRASMTSTPP--------------PPVPPPPPPPAT 361
Query: 413 KPKFLKIAEEDPPREAAMPGLFVPPVAP-RPPALKLPVPEAMARPAV-------LPRPEK 464
+ + P + A PG+ P P PP ++ P A A P LP+ E
Sbjct: 362 ALQAPAVPPPPAPLQIA-PGVLHPAPPPIAPPLVQPSPPVARAAPVCETVPVHPLPQGEV 420
Query: 465 PQLPHLQRSPP 475
LP PP
Sbjct: 421 QGLPPPPPPPP 431
>gi|4507913 Wiskott-Aldrich syndrome protein family member 1 [Homo
sapiens]
Length = 559
Score = 66.6 bits (161), Expect = 6e-11
Identities = 63/226 (27%), Positives = 80/226 (35%), Gaps = 49/226 (21%)
Query: 243 PDSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPPKHGLP 302
P SP GR + P PPPP+P+ A S S TS P P+ PPPPP
Sbjct: 308 PQSPATGRTPVFVSPTPPPPPPPLPS----ALSTSSLRASMTSTPPPPVPPPPPP----- 358
Query: 303 DVGLAAEDSKRDPLCPRRAEPCPRVPATPRRMSDPPLSTMPTAPGL---RKPPCFRESAS 359
P A P VP PP + + APG+ PP
Sbjct: 359 ---------------PATALQAPAVP--------PPPAPLQIAPGVLHPAPPPIAPPLVQ 395
Query: 360 PSPEPWTPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSEPPP-VPANKPKFLK 418
PSP P C T + + L P PP PPP + + P +
Sbjct: 396 PSP-PVARAAPVCETVPVHPLPQGEVQG--------LPPPPPPPPLPPPGIRPSSPVTVT 446
Query: 419 IAEEDP----PREAAMPGLFVPPVAPRPPALKLPVPEAMARPAVLP 460
P P + PG VP + P PP+ +P E P+ LP
Sbjct: 447 ALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQVIPASEPKRHPSTLP 492
Score = 51.2 bits (121), Expect = 3e-06
Identities = 54/191 (28%), Positives = 66/191 (34%), Gaps = 46/191 (24%)
Query: 293 PPPPPKHGLPDVGLAAEDSKRDPLCPRRAEPCPRVPATPRRMSDPPLSTMPTAPGLRKPP 352
PPPPP HG A D+K P C A + P +P + P
Sbjct: 279 PPPPPMHG-------AGDAKPIPTCISSATGL--------------IENRPQSPATGRTP 317
Query: 353 CFRESASPSPEPWTPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSEPPPVPAN 412
F P P P P A STSS T+T PP PPP PA
Sbjct: 318 VFVSPTPPPPPPPLPS--ALSTSSLRASMTSTPP--------------PPVPPPPPPPAT 361
Query: 413 KPKFLKIAEEDPPREAAMPGLFVPPVAP-RPPALKLPVPEAMARPAV-------LPRPEK 464
+ + P + A PG+ P P PP ++ P A A P LP+ E
Sbjct: 362 ALQAPAVPPPPAPLQIA-PGVLHPAPPPIAPPLVQPSPPVARAAPVCETVPVHPLPQGEV 420
Query: 465 PQLPHLQRSPP 475
LP PP
Sbjct: 421 QGLPPPPPPPP 431
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 64.3 bits (155), Expect = 3e-10
Identities = 85/287 (29%), Positives = 105/287 (36%), Gaps = 44/287 (15%)
Query: 243 PDSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPPKHGLP 302
P +P P + A M P A PP P P P + T P L PPPK G P
Sbjct: 1094 PATPSP---KGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPK-GAP 1149
Query: 303 DVGLAAEDSKRDPLCPRRAEPCPRVPA-TPRR----MSDPPLSTMPTAPGLRKPPCFRES 357
A S + L + P PA TP ++ P PT P P
Sbjct: 1150 TTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGL 1209
Query: 358 ASPSPE--PWTPGHGACSTSSAAIMATATSRNCDKLKSFHL-SPRGPPTSEP----PPVP 410
A+PSP+ P TP A S +AT + + + SP+G P + P P P
Sbjct: 1210 ATPSPKGAPTTPA--ATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPP 1267
Query: 411 ANKPKFLKIAEEDPPREAA-MPGLFVPPV------------APRPPALKLPVPE------ 451
A P LK PP + A P + PP AP PPA P P+
Sbjct: 1268 AATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTP 1327
Query: 452 ----AMARPAVLPRPEK--PQLPHLQRSPPDGQSFRSFSFEKPRQPS 492
A PAV P K P LP S G + S S E P P+
Sbjct: 1328 PPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPS-SKEGPTPPA 1373
Score = 55.8 bits (133), Expect = 1e-07
Identities = 73/288 (25%), Positives = 111/288 (38%), Gaps = 29/288 (10%)
Query: 199 TSDSSSDTDSFYGAVERPVD-ISLSPYPTDNEDYEHDDEDDSYLE---PDSPEPGRLEDA 254
T S+ D+ G + PV + S P ++ ++ + + P SP+ A
Sbjct: 810 TKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSA 869
Query: 255 L--MHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPPKHGLPDVGLAAEDSK 312
+ + P PP TP P+ ++P F +GP P PK P + + + K
Sbjct: 870 VTPLSPKGVTLPPKETPT-PSVVNLP----FPKEGPAT----PAPKQA-PALSMTSSSPK 919
Query: 313 RDPLCPRRAEPCPR-VPATP--RRMSDPPLSTMPTAPGLRKPPCFRESASP--SPEPWTP 367
+ RA P P+ +PA+P + PP +T P+ G P + + +P + P
Sbjct: 920 K-----ARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPK 974
Query: 368 GHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSEPPPVPANKPKFLKIAEEDPPRE 427
G A + A A + K SP+G PT PP V PK A P
Sbjct: 975 GGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPT--PPAVTPPSPKGSPAATPFPKGA 1032
Query: 428 AAMPGLFVPPVAPRPPALKLPVPEAMARPAVLPRPE-KPQLPHLQRSP 474
+ P P P A LP A LP P+ P P L+ +P
Sbjct: 1033 STPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAP 1080
Score = 53.5 bits (127), Expect = 6e-07
Identities = 63/243 (25%), Positives = 84/243 (34%), Gaps = 21/243 (8%)
Query: 243 PDSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPPKHGLP 302
P SP+ G A P P PP TP P S P P + PP PK G P
Sbjct: 1294 PPSPKGG---PATSPPKGAPTPPAATPPSPKGS--PGTPPPKGAPTPPAVTPPSPK-GTP 1347
Query: 303 DVGLAAEDSKRDPLCPRRAEPCPRVPATPRRMSDPPLSTMPTAPGLRKPPCFRESASPSP 362
+ SK P P E ATP P ++ G P + SP+
Sbjct: 1348 TLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAV 1407
Query: 363 EPWTP---------GHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSEPPPVPANK 413
P +P GA + S + A + K +P+G P +
Sbjct: 1408 IPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTL 1467
Query: 414 PKFLKIAEEDPPREAAMPGLFVPPVAPRPPALKLPVPEAMARPAVLPRPEK--PQLPHLQ 471
P + ++PP + P AP PA P+ A PAV+P K P P +
Sbjct: 1468 PAVTPPSPKEPPAPKQVATSSSPKKAPATPA---PM-GAPTLPAVIPSSPKEVPATPSSR 1523
Query: 472 RSP 474
R P
Sbjct: 1524 RDP 1526
Score = 52.4 bits (124), Expect = 1e-06
Identities = 67/230 (29%), Positives = 78/230 (33%), Gaps = 31/230 (13%)
Query: 243 PDSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPPKHGLP 302
P SP+ G A P P PP TP P S P A F P PP G P
Sbjct: 993 PPSPKGG---PATPSPKGAPTPPAVTPPSPKGS--PAATPFPKGASTPPAATPPSPKGSP 1047
Query: 303 DVGLAAEDSKRDPLCPRRAEPCPRV-PATPRRMSDPPLSTMPTAPGLRKPPCFRESASPS 361
A K P P P P+ PATP L PT P P A+PS
Sbjct: 1048 ---AATPLPKGAPTTPAATLPSPKGGPATPS------LKGAPTPPAATPPSPKGGPATPS 1098
Query: 362 PEPWTPGHGACSTSSAAIMATATSRNCDKL-KSFHLSPRG----PPTSEPPPVPANKPKF 416
P+ A S +AT + + SP+G PP P PA P
Sbjct: 1099 PKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPS 1158
Query: 417 LKIAEEDPPREAAMPGLFVPPVAPRPPALKLPVPE-AMARPAVLPRPEKP 465
K PP P AP PA P P+ +A P+ P P
Sbjct: 1159 PKGGLATPP----------PKGAPTTPAATPPSPKGGLATPSPKGAPTTP 1198
Score = 50.4 bits (119), Expect = 5e-06
Identities = 72/275 (26%), Positives = 100/275 (36%), Gaps = 26/275 (9%)
Query: 241 LEPDSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPP----- 295
+ P SP+ G + P P +P+K + + R + T G L PP
Sbjct: 1384 MTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPS-KGDLTPPAVTPVS 1442
Query: 296 ---PPKHGLPDVGLAAEDSKRDPLCPRRAEPCPRVPATPRRM---SDPPLSTMPTAP-GL 348
P P G A SK DP P P P+ P P+++ S P + AP G
Sbjct: 1443 LKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGA 1502
Query: 349 RKPPCFRESASPSPEPWTPGHGACSTSSAAIMAT----ATSRNCDKLKSFHLSPRGPPTS 404
P S SP P TP + A + + AT + L ++ P +
Sbjct: 1503 PTLPAVIPS-SPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKT 1561
Query: 405 EPPPVPANKPKFLKIAEEDPPREAAMPGLFVPPVAPR----PPALKLPVP-EAMARPAVL 459
P P P E P A P + +P+ PPA+ P P EA PAV
Sbjct: 1562 PAIPTPKEAPATPSSKEASSP-PAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVT 1620
Query: 460 -PRPEK-PQLPHLQRSPPDGQSFRSFSFEKPRQPS 492
P PEK P P + +P S + P P+
Sbjct: 1621 PPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPA 1655
Score = 35.8 bits (81), Expect = 0.12
Identities = 51/227 (22%), Positives = 79/227 (34%), Gaps = 29/227 (12%)
Query: 243 PDSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPPKHG-- 300
P P L++ L+ P P + P + P+ ++ P P+ P P K+G
Sbjct: 1673 PAKKGPTALKEVLVAPAPESTPIITAPTRKG----PQTKKSSATSP-PICPDPSAKNGSK 1727
Query: 301 ------LPDVGLAAEDSKRDPLCPRRAEPCPRVP-ATPRRMSDPPLSTMPTAPGLRKPPC 353
P L + + A P+ P A P + PL+ L KP
Sbjct: 1728 GPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPES 1787
Query: 354 FRESASPSPEPWTPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSEP--PPVPA 411
SA+PSP P +A + + F S G P P PA
Sbjct: 1788 ASVSAAPSPPVSLP------------LAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPA 1835
Query: 412 NKPKFLKIAEEDPPREAAMPGLFVPPVAPRPPALKLPVPEAMARPAV 458
++ + L + + P +P V P P + +PVP A+ V
Sbjct: 1836 DEDELLPLIPPE-PISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQPV 1881
Score = 33.1 bits (74), Expect = 0.78
Identities = 65/269 (24%), Positives = 95/269 (35%), Gaps = 32/269 (11%)
Query: 259 PAYPPPPVPTPRKPAFSDMPRAHSFTSK---GPGPLLPPPP--------PKHGLPDVGLA 307
P PPP P P++ S +A F S PL P P P P+
Sbjct: 43 PTLPPPCSPAPQQCPLSAANQASPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTF 102
Query: 308 AEDSKRDPLCPRR---AEP--CPRVPATPRRMSDPPLSTMPTAP-GLRKPPCFRESASPS 361
+ P+ P A P P + TP S PL+ + AP ++K F + S
Sbjct: 103 LPNLIGPPISPAALALASPMIAPTLKGTP--SSSAPLALVALAPHSVQKSSAFPPNLLTS 160
Query: 362 PEPWTPGH-GACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSEPPPVPANKPKFLKIA 420
P G+ T SA I + N +K+ S + P T PP + + P
Sbjct: 161 PPSVAVAESGSVITLSAPIAPSEPKTNLNKVPS-EVVPNPKGTPSPPCIVSTVPYHCV-- 217
Query: 421 EEDPPREAAMPGLFVPPVAPRPPALKLPVPEA--MARPAVLPRPEKPQLPHLQR--SPPD 476
P + G+ P L + P+ +VL P+ P L+ SPP
Sbjct: 218 ---TPMASIQSGVASLPQTTPTTTLAIASPQVKDTTISSVLISPQNPGSLSLKGPVSPPA 274
Query: 477 GQSFRSFSFEKPRQPSQADTGGDDSDEDY 505
S + S P S T G ++ D+
Sbjct: 275 ALSLSTQSL--PVVTSSQKTAGPNTPPDF 301
>gi|221139926 NHS-like 1 [Homo sapiens]
Length = 1606
Score = 63.2 bits (152), Expect = 7e-10
Identities = 78/320 (24%), Positives = 117/320 (36%), Gaps = 62/320 (19%)
Query: 250 RLEDALMHPPAYPPPPVPTPRKPAFSD----MPRAHSFTSKGPG------PLLPPPPPKH 299
+L+ A+ PPA PPPPVP+P P +D +P T G P+ PPPPP+
Sbjct: 919 KLDPAVGSPPAPPPPPVPSPPFPCPADRSPFLPPPPPVTDCSQGSPLPHSPVFPPPPPEA 978
Query: 300 GL-----PDVGLAAEDSKRDPLCP-------------RRAEPCPRVPATPRRMSD--PPL 339
+ PD L+ P+ P +EP P P P+ M D PP
Sbjct: 979 LIPFCSPPDWCLSPPRPALSPILPDSPVSLPLPPPLLPSSEPPPAPPLDPKFMKDTRPPF 1038
Query: 340 STM---PTAPGLRKPPCFRESASPSPEPWTPGHG-------ACSTSSAAIMATATSRNCD 389
+ ++ G +PP +E S P P +S A A + R
Sbjct: 1039 TNSGQPESSRGSLRPPSTKEETSRPPMPLITTEALQMVQLRPVRKNSGAEAAQLSERTAQ 1098
Query: 390 KLKS-----FHLSPRG-----------PPTSEPPPVPANKPKFLKIAEEDPPREAAMPGL 433
+ ++ +HL P S+P V ++ P K + + AA G
Sbjct: 1099 EQRTPVAPQYHLKPSAFLKSRNSTNEMESESQPASVTSSLPTPAKSSSQGDHGSAAERG- 1157
Query: 434 FVPPVAPRPPALKLPVPEAMARPAVLPRPEKPQLPHLQRSPPDGQSFRSFSFEKPRQPSQ 493
PV+ P A EA P+ P P+ ++ PP + + F P Q
Sbjct: 1158 --GPVSRSPGAPSAGEAEARPSPSTTPLPDSSP---SRKPPPISKKPKLFLVVPPPQKDF 1212
Query: 494 ADTGGDDSDEDYEKVPLPNS 513
A ++ E VP P +
Sbjct: 1213 AVEPAENVSEALRAVPSPTT 1232
Score = 42.0 bits (97), Expect = 0.002
Identities = 44/150 (29%), Positives = 63/150 (42%), Gaps = 31/150 (20%)
Query: 340 STMPTAPGLRKPPCFRESASPS-----PEPWTPGHGACSTSSAAIMATATSRNCDK---- 390
S PTA L P F +S SP+ P+P P + SS +I +++TS +
Sbjct: 856 SNTPTA--LTPVPVFLKSVSPANGKGKPKPKVPERKSSLISSVSISSSSTSLSSSTSTEG 913
Query: 391 ---LKSFHLSPRGPPTSEPPPVPANKPKFLKIAEEDPPREAAMPGLFVPPVAPRPPALK- 446
+K + PP PPPVP+ P F A+ P F+PP P +
Sbjct: 914 SGTMKKLDPAVGSPPAPPPPPVPS--PPFPCPADRSP---------FLPPPPPVTDCSQG 962
Query: 447 LPVPEAMARPAVLPRPEKPQLPHLQRSPPD 476
P+P + P P P + +P SPPD
Sbjct: 963 SPLPHS---PVFPPPPPEALIPFC--SPPD 987
Score = 39.3 bits (90), Expect = 0.011
Identities = 62/267 (23%), Positives = 92/267 (34%), Gaps = 28/267 (10%)
Query: 243 PDSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPPKHGLP 302
PDSP L L+ PP P P+ + P +S + L PP K
Sbjct: 1002 PDSPVSLPLPPPLLPSSEPPPAPPLDPKFMKDTRPPFTNSGQPESSRGSLRPPSTK---- 1057
Query: 303 DVGLAAEDSKRDPLCPRRAEPCPRVPATPRRMSDPPLSTM-----------PTAPGLR-K 350
E++ R P+ E V P R + + P AP K
Sbjct: 1058 ------EETSRPPMPLITTEALQMVQLRPVRKNSGAEAAQLSERTAQEQRTPVAPQYHLK 1111
Query: 351 PPCFRESASPSPEPWTPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSEPPPVP 410
P F +S + + E + A TSS A ++S+ + RG P S P P
Sbjct: 1112 PSAFLKSRNSTNEMESESQPASVTSSLPTPAKSSSQG----DHGSAAERGGPVSRSPGAP 1167
Query: 411 ANKPKFLKIAEEDPPREAAMPGLFVPPVAPRPPALKLPVPEAMARPAVLPRPEKPQLPHL 470
+ + + P + P PP++ + P L L VP AV P +
Sbjct: 1168 SAGEAEARPSPSTTPLPDSSPSRKPPPIS-KKPKLFLVVPPPQKDFAVEPAENVSEALRA 1226
Query: 471 QRSPPDGQSFRSFSFEKPRQPSQADTG 497
SP G+ S + ++ S A G
Sbjct: 1227 VPSPTTGEE-GSVHSREAKESSAAQAG 1252
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 63.2 bits (152), Expect = 7e-10
Identities = 67/242 (27%), Positives = 88/242 (36%), Gaps = 32/242 (13%)
Query: 243 PDSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPPKHGLP 302
P P+P L+ A PP V PRK A + S P P PP P P
Sbjct: 260 PSQPKPKGLQ-------ALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAP--P 310
Query: 303 DVGLAAEDSKRDPLCPRRAEPCPRVPATPRRMSDPPLSTMPTAP-----GLRKPPCFRES 357
+ P + P + AT + PPLS + T P L PP
Sbjct: 311 SLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPP 370
Query: 358 ASPSPEPWTPGHGACSTSSAAIMATATSRNCDKLKSFHL--SPRGPPTSEPPPVPANKPK 415
+ P+ P +P +AT + + + L + HL +P PP S P P + P
Sbjct: 371 SPPASPPLSP------------LATPSPQAPNAL-AVHLLQAPFSPPPSPPVQAPFSPPA 417
Query: 416 FLKIAEEDPPREAAMPGLFVPP--VAPRPPALKLPVPEAMARPAVLPRPEKPQLPHLQRS 473
++ P A P L PP V P PPA P A P P P L L +
Sbjct: 418 SPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPL-QLAKP 476
Query: 474 PP 475
PP
Sbjct: 477 PP 478
Score = 58.5 bits (140), Expect = 2e-08
Identities = 72/258 (27%), Positives = 92/258 (35%), Gaps = 34/258 (13%)
Query: 243 PDSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGP-GPLLPPPP---PK 298
P SP L PPA PP T + HSF P PL PPP P
Sbjct: 303 PPSPSAPPSLQTLPSPPATPPSQATTSL--GSPTLQATHSFLPSPPLSPLATPPPQAPPA 360
Query: 299 HGLPDVGLAAEDSKRDPLCPRRAEPCPRVP-ATPRRMSDPPLSTMPTAPGLRKPPCFRES 357
LP + PL P A P P+ P A + P S P+ PP
Sbjct: 361 LALPPLQAPPSPPASPPLSPL-ATPSPQAPNALAVHLLQAPFSPPPS------PPVQAPF 413
Query: 358 ASPSPEPWTPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSE-PPPVPANKPKF 416
+ P+ P +P S + ++ A S +SP P + PPP+ A +
Sbjct: 414 SPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQL 473
Query: 417 LKIAEEDPPREAAMP--GLFVPPV-----APRPPALKLPV----------PEAMARPAVL 459
K + PP A P L PP AP P+ LP+ P +A P +
Sbjct: 474 AKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQ 533
Query: 460 PRPEKPQLPHLQ--RSPP 475
P P P LQ R PP
Sbjct: 534 VPPSPPASPTLQAPRRPP 551
Score = 56.2 bits (134), Expect = 9e-08
Identities = 72/272 (26%), Positives = 96/272 (35%), Gaps = 24/272 (8%)
Query: 241 LEPDSPEPGRLEDALMHPP--AYPPPPVPTPRKPAFSDMPRAHSFTSKG--PGPLLPPPP 296
L P + P + AL PP A P PP P P + P+A + + P PPP
Sbjct: 347 LSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPS 406
Query: 297 PKHGLPDVGLAAEDSKRDPLCPRRAEP---CPRVPATPRRMSDPPLSTMPTAPGLRKPPC 353
P P A+ P +A P P + P + PP+S T P PP
Sbjct: 407 PPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPL 466
Query: 354 FR---ESASPSPEP----WTPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSEP 406
+ A P P+ TP A + A+ A S +SP P +
Sbjct: 467 AAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAP---FSPSASLPMSPLATPPPQA 523
Query: 407 PPVPANKPKFLKIAEEDPPREAAMPGLFVPPVAPRP-PALKLPVPEAMARPAVLPRPEKP 465
PPV A L++ PP A P L P P P P + P A P P
Sbjct: 524 PPVLA--APLLQV----PPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPS 577
Query: 466 QLPHLQRSPPDGQSFRSFSFEKPRQPSQADTG 497
+ P S PD S + P + D+G
Sbjct: 578 RSPSSTLSGPDLAGHSSSATSTPEELRGYDSG 609
Score = 47.4 bits (111), Expect = 4e-05
Identities = 63/238 (26%), Positives = 81/238 (34%), Gaps = 53/238 (22%)
Query: 243 PDSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPP------ 296
P SP PP PPP+ P P+A + P LP PP
Sbjct: 443 PPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQ 502
Query: 297 ----PKHGLPDVGLAAEDSKRDPLCPRRAEPCPRVPAT---------PRRMSDP------ 337
P LP LA + P+ A P +VP + PRR P
Sbjct: 503 APFSPSASLPMSPLATPPPQAPPVL---AAPLLQVPPSPPASPTLQAPRRPPTPGPDTSV 559
Query: 338 --PLSTMPTAPGLRKPPCFRESASPSPEPWTPGHGACSTSSAAIMATATSRNCDKLKSFH 395
P T+ APG PP R +S P GH + +TS+ ++L+ +
Sbjct: 560 SGPRLTLALAPGPPPPPS-RSPSSTLSGPDLAGHSSSATSTP-----------EELRGYD 607
Query: 396 LSPRGPPTSEPPPVPANKPKFLKIAEEDPPREAAMPGLFVPPVAPR-PPALKLPVPEA 452
P G + PPP AE AA PP+A R P LP P A
Sbjct: 608 SGPEGGAAASPPP----------DAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPA 655
Score = 40.4 bits (93), Expect = 0.005
Identities = 77/301 (25%), Positives = 99/301 (32%), Gaps = 58/301 (19%)
Query: 242 EPDSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPP------- 294
+P + G + A + A P T R PA RA + PGP+ P
Sbjct: 56 KPLAERAGGIGGATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTT 115
Query: 295 ---PPPKHGL-------PDVGLAAEDSKRDPL-CPRRAEPCPRVPATPRRMSDPPLSTMP 343
P + GL G A E KR L R + P TP
Sbjct: 116 RPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAG 175
Query: 344 TAPGLRKPPCFRESASPSPEPWTPG----------HGACSTSSAAIMATATSRNCDKLKS 393
T GL +P + S P P T G H S AA + + S
Sbjct: 176 TEVGLPRP-----APSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPAS 230
Query: 394 FHLSPRGPPTSEP----------PPVPAN----KPK---FLKIAEEDPPREAAMPGLFVP 436
LS P S P P PA+ KPK L+ + PPR+ A P L
Sbjct: 231 RSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPAL--G 288
Query: 437 PVAPRPPALKLP--VPEAMARPAVLPRPEKPQLPHLQRS----PPDGQSFRSFSFEKPRQ 490
P++ P A P P A P++ P P P Q + P Q+ SF P
Sbjct: 289 PLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLS 348
Query: 491 P 491
P
Sbjct: 349 P 349
Score = 36.2 bits (82), Expect = 0.092
Identities = 51/181 (28%), Positives = 59/181 (32%), Gaps = 35/181 (19%)
Query: 284 TSKGPGPLLPPPPPKHGLPDVGLAAEDSKRDPLCPRRA--------EPCPRVPATPRRMS 335
T + PG PPPP V AA R PL R E PR A P R S
Sbjct: 26 TPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPR--AGPTRTS 83
Query: 336 DPPLSTMPTAPGLRKPPCFRES---------ASPSPEPWTPGHGACSTSSAAIMATATSR 386
PP S G R PP S AS + P G S+ +A +
Sbjct: 84 RPPAS----GRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKAT 139
Query: 387 NCDKLKSFHLSPR----GPPTSEPPPVPANKPKFLKIAEEDPPREAAMPGLFVPPVAPRP 442
K + R GP P P A + + E PR A P PRP
Sbjct: 140 EAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAG-TEVGLPRPA-------PSARPRP 191
Query: 443 P 443
P
Sbjct: 192 P 192
Score = 31.6 bits (70), Expect = 2.3
Identities = 39/141 (27%), Positives = 50/141 (35%), Gaps = 15/141 (10%)
Query: 243 PDSPEPGRLEDALMHPPAYPP--PPVPTPRKPAFSDMPRAHS----FTSKGPGPLLPPPP 296
P P L L+ P PP P + PR+P + S + PGP PPPP
Sbjct: 519 PPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGP--PPPP 576
Query: 297 ---PKHGL--PDVGLAAEDSKRDPLCPRRAEPCPRVPATPRRMSDPPLSTMPTAPGLR-- 349
P L PD+ + + P R + P A D L+ A R
Sbjct: 577 SRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGP 636
Query: 350 KPPCFRESASPSPEPWTPGHG 370
PP A +P PW P G
Sbjct: 637 APPLAFRGAPGAPLPWPPATG 657
>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
sapiens]
Length = 2715
Score = 63.2 bits (152), Expect = 7e-10
Identities = 70/279 (25%), Positives = 108/279 (38%), Gaps = 44/279 (15%)
Query: 227 DNEDYEHDDEDD-SYLEPDSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTS 285
+ +D E +++++ + E P + E L PP PP P P P P S P
Sbjct: 372 EEKDKEGEEKEERAVAEEMMPAAEKEEAKLPPPPLTPPAPSPPPPLPPPSTSP------- 424
Query: 286 KGPGPLLPPPPPKHGLPDVGLAAEDSKRDPLCPRRAEPCPRVPAT-PRRMSDPPLSTMPT 344
P PL PPPPP P + ++ + P P VPAT R+ PPL+
Sbjct: 425 --PPPLCPPPPPPVSPPPLPSPPPPPAQE---EQEESPPPVVPATCSRKRGRPPLTPSQR 479
Query: 345 APGLRKPPCFRESASPSPEPWTPGHGACSTSS------AAIMATATSRNCDKLKSFHLSP 398
A RE+A PE +P ST++ + +A ++ ++ F +
Sbjct: 480 AE--------REAARAGPEGTSPPTPTPSTATGGPPEDSPTVAPKSTTFLKNIRQFIM-- 529
Query: 399 RGPPTSEPPPVPANKPKFLK----IAEEDPPR--EAAMPGLFVPPVAPRPPALKLPVPEA 452
P V A + +K +EDPP+ + + + PP+ PP + P P
Sbjct: 530 --------PVVSARSSRVIKTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAPVP 581
Query: 453 MARPAVLPRPEKPQLPHLQRSPPDGQSFRSFSFEKPRQP 491
A P LP +RS +FR S + P
Sbjct: 582 SPPRAPTPPSTPVPLPEKRRSILREPTFRWTSLTRELPP 620
Score = 43.5 bits (101), Expect = 6e-04
Identities = 62/211 (29%), Positives = 77/211 (36%), Gaps = 51/211 (24%)
Query: 212 AVERPVDISLSPYPTDNEDYEHDDE-DDSYLEPDSPE---PGRLEDALMHPPAYPPPPVP 267
A E I SP P+ D D L P +PE P + D + P + PP P
Sbjct: 1797 AAEENQTIVHSPAPSSEPPGGEDPPLDTDVLVPGAPERHSPIQNLDPPLRPDSGSAPP-P 1855
Query: 268 TPRKPAFSDMPRAHSFTSKGP------GPLLPPPPPK---HGLPDVGLAAEDSKRDPLCP 318
PR + + + + S+ P GPL P P H +P VG D P
Sbjct: 1856 APRSFSGARIKVPNYSPSRRPLGGVSFGPLPSPGSPSSLTHHIPTVG--DPDFPAPPRRS 1913
Query: 319 RRAEP-CPRVPATPRRMSDPPLSTMPTAPGLRKPPCFRESASPSPEPWTPGHGACSTSSA 377
RR P PR P P R + PPL T +P LR PP +S
Sbjct: 1914 RRPSPLAPRPP--PSRWASPPLKT---SPQLRVPP---------------------PTSV 1947
Query: 378 AIMATATSRNCDKLKSFHLSPRGPPTSEPPP 408
T TS L+P GP S PPP
Sbjct: 1948 VTALTPTSGE--------LAPPGPAPSPPPP 1970
Score = 40.8 bits (94), Expect = 0.004
Identities = 50/174 (28%), Positives = 66/174 (37%), Gaps = 34/174 (19%)
Query: 258 PPAYPPPPVPT-PRKPAFSD----MPRAHSFTS-----KGPGPLLPPPPPKHGLPDVGLA 307
PPA PPPP P+ P PA S + RA FT K +L PPP G P+
Sbjct: 622 PPAPPPPPAPSPPPAPATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPP--LGAPE---- 675
Query: 308 AEDSKRDPLCPRRAEPCPRVPATPRRMSDPPLSTMPTAPGLRKPPCFRESASPSPEPWTP 367
A + + P AEP PR +S P + + T P + SP
Sbjct: 676 APEPEPPPADDSPAEPEPRAVGRTNHLSLPRFAPVVTTP-------VKAEVSP------- 721
Query: 368 GHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTS---EPPPVPANKPKFLK 418
HGA + S+ + L++ L PP +PPP P P K
Sbjct: 722 -HGAPALSNGPQTQAQLLQPLQALQTQLLPQALPPPQPQLQPPPSPQQMPPLEK 774
Score = 33.1 bits (74), Expect = 0.78
Identities = 46/182 (25%), Positives = 60/182 (32%), Gaps = 43/182 (23%)
Query: 263 PPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPPKHGLPDVGLAAEDSKRDPLCPRRAE 322
PPPV P P S+T LPP P LP VG+ R
Sbjct: 2212 PPPVKQPPLPPTISPTAPTSWT-------LPPGPLLGVLPVVGVV------------RPA 2252
Query: 323 PCPRVPATPRRMSDPPLSTMPTAPGLRKPPCFRESASPSPEPW----------------- 365
P P P +S P S A +++ F + P+P P+
Sbjct: 2253 PPPPPPPLTLVLSSGPASPPRQAIRVKRVSTFSGRSPPAPPPYKAPRLDEDGEASEDTPQ 2312
Query: 366 TPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSEPPPVP-ANKPKFLKIAEEDP 424
PG G+ S M T T R L G P E P P + L + E+ P
Sbjct: 2313 VPGLGSGGFSRVR-MKTPTVRGV-----LDLDRPGEPAGEESPGPLQERSPLLPLPEDGP 2366
Query: 425 PR 426
P+
Sbjct: 2367 PQ 2368
Score = 32.7 bits (73), Expect = 1.0
Identities = 50/190 (26%), Positives = 65/190 (34%), Gaps = 30/190 (15%)
Query: 325 PRVPATPRRMSDPPLST---MPTAPGLRKP-----PCFRESASPSPEPWTPGHGACSTSS 376
P + P DPPL T +P AP P P R + +P P S S
Sbjct: 1808 PAPSSEPPGGEDPPLDTDVLVPGAPERHSPIQNLDPPLRPDSGSAPPP-----APRSFSG 1862
Query: 377 AAIMATATSRNCDKLKSFHLSPR---GPPTSEPPPVPA-NKPKFLKIAEEDPPREAAMPG 432
A I S + L P G P+S +P P F PPR + P
Sbjct: 1863 ARIKVPNYSPSRRPLGGVSFGPLPSPGSPSSLTHHIPTVGDPDF-----PAPPRRSRRPS 1917
Query: 433 LFVPPVAPRPPALKLPVPEAMARPAVLPRPEKPQLPHLQRSPPDGQSFRSFSFEKPRQPS 492
P+APRPP + P P + P + L +P G+ + P P
Sbjct: 1918 ----PLAPRPPPSRWASPPLKTSPQLRVPPPTSVVTAL--TPTSGE--LAPPGPAPSPPP 1969
Query: 493 QADTGGDDSD 502
D G D D
Sbjct: 1970 PEDLGPDFED 1979
Score = 32.3 bits (72), Expect = 1.3
Identities = 26/84 (30%), Positives = 33/84 (39%), Gaps = 7/84 (8%)
Query: 239 SYLEPDSPEPGRLEDALMHPPAYPPPPVPT-------PRKPAFSDMPRAHSFTSKGPGPL 291
S+ P P G L + PA PPPP P P P + T G P
Sbjct: 2231 SWTLPPGPLLGVLPVVGVVRPAPPPPPPPLTLVLSSGPASPPRQAIRVKRVSTFSGRSPP 2290
Query: 292 LPPPPPKHGLPDVGLAAEDSKRDP 315
PPP L + G A+ED+ + P
Sbjct: 2291 APPPYKAPRLDEDGEASEDTPQVP 2314
Score = 30.8 bits (68), Expect = 3.9
Identities = 33/124 (26%), Positives = 42/124 (33%), Gaps = 26/124 (20%)
Query: 210 YGAVERPVD-ISLSPYPTDNEDYEHDDEDDSYLEPDSPEPGRLEDALMHPPAYPPPP--- 265
Y RP+ +S P P+ + +PD P P R P A PPP
Sbjct: 1870 YSPSRRPLGGVSFGPLPSPGSPSSLTHHIPTVGDPDFPAPPR-RSRRPSPLAPRPPPSRW 1928
Query: 266 ------------VPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPPKHGLPDV-------GL 306
VP P + P + GP P PPPP+ PD GL
Sbjct: 1929 ASPPLKTSPQLRVPPPTSVVTALTPTSGELAPPGPAP--SPPPPEDLGPDFEDMEVVSGL 1986
Query: 307 AAED 310
+A D
Sbjct: 1987 SAAD 1990
>gi|149773456 hypothetical protein LOC643314 [Homo sapiens]
Length = 1427
Score = 62.8 bits (151), Expect = 9e-10
Identities = 90/345 (26%), Positives = 121/345 (35%), Gaps = 51/345 (14%)
Query: 243 PDSPEPGRLEDALMHP--PAYPPPPVPTPRKPAFSDMPRAHSFTSKGP-GPLLPPPPPKH 299
P EP A+ P P P VPTP +P P A T + P P P P+
Sbjct: 1047 PTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPT---SPAAAVPTPEEPTSPAAAVPTPEE 1103
Query: 300 GLPDVGLAAEDSKRDPLCPRRAEPCPRVPATPRRMSDPPLSTMPTAPGLRKP-------- 351
P AA + +P P A P P PA+P P AP + P
Sbjct: 1104 --PTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAV 1161
Query: 352 --PCFRESASPSPEPWTPGHGACSTSSAAIMATATSRNCD---------KLKSFHLSPRG 400
P ESASP+ TP A + A + TS L+ F
Sbjct: 1162 AVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVATLEEFTSPAAS 1221
Query: 401 PPTSEPPPVPANKPKFLKIAEEDPPREAAMPGLFVPPV-APRPPALKLPVPEAMARPAV- 458
PTSE P A A P E P VP + P A + PE ++ PA
Sbjct: 1222 VPTSEEPASLA--------AAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSPAAS 1273
Query: 459 LPRPEKPQLPHLQRSPPDGQSFRSFSFEKPRQPSQADTGGDDSDEDYEKVPLPNSVFVNT 518
+P PE+P P S + E+P P+ A + + VP P +
Sbjct: 1274 VPTPEEPASPAAAVS----------NLEEPASPAAAVPTPEVAAIPAASVPTPEVPAIPA 1323
Query: 519 TESCEVERLFKATSPRGEPQDGLYCIRNSSTKSGKVLVVWDETSN 563
+E + SP G P G+ +S S + V +E S+
Sbjct: 1324 AAVPPMEEV----SPIGVPFLGVSAHTDSVPISEEGTPVLEEASS 1364
Score = 57.8 bits (138), Expect = 3e-08
Identities = 61/245 (24%), Positives = 81/245 (33%), Gaps = 49/245 (20%)
Query: 252 EDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPPKHGLPDVGLAAEDS 311
ED P P V P +P + + + P +P P
Sbjct: 967 EDGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTP---------------- 1010
Query: 312 KRDPLCPRRAEPCPRVPATPRRMSDPPLSTMPTAPGLRKP----PCFRESASPSPEPWTP 367
+P P A P P P +P PP PT+P P P +A P+PE
Sbjct: 1011 -EEPTSPAAAVPTPEEPTSPAAAVPPP--EEPTSPAAAVPTPEEPTSPAAAVPTPEE--- 1064
Query: 368 GHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSEPPPVPANKPKFLKIAEEDPPRE 427
TS AA + T P P + P P P A P E
Sbjct: 1065 -----PTSPAAAVPTPE------------EPTSPAAAVPTPEEPTSP----AAAVPTPEE 1103
Query: 428 AAMPGLFVP-PVAPRPPALKLPVPEAMARP-AVLPRPEKPQLPHLQRSPPDGQSFRSFSF 485
P VP P P PA +P PE A P A +P PE+P P P+ + + +
Sbjct: 1104 PTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAV 1163
Query: 486 EKPRQ 490
P +
Sbjct: 1164 PTPEE 1168
Score = 41.6 bits (96), Expect = 0.002
Identities = 55/218 (25%), Positives = 74/218 (33%), Gaps = 21/218 (9%)
Query: 330 TPRRMSDPPLSTMPTAPGLRKPPCFRESASPSPEPWTPGHGACSTSSAAIMATATSRNCD 389
T +S P +T+P +A SPE P A T S
Sbjct: 897 TAAAVSAPERATVPAVTVSVPEGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGFSPEWA 956
Query: 390 KLKSFHLSPRGPPTSEPPPVPANKPKFLKIAEEDP---------PREAAMPGLFVP-PVA 439
L T E P PA A E+P P E A P VP P
Sbjct: 957 ALAITVPITEEDGTPEGPVTPATTVH----APEEPDTAAVRVSTPEEPASPAAAVPTPEE 1012
Query: 440 PRPPALKLPVPEAMARP-AVLPRPEKPQLPHLQRSPPDGQSFRSFSF---EKPRQPSQAD 495
P PA +P PE P A +P PE+P P P+ + + + E+P P+ A
Sbjct: 1013 PTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAV 1072
Query: 496 TGGDDSDEDYEKVPLPNSVFVNTTESCEVERLFKATSP 533
++ VP P T+ + V + TSP
Sbjct: 1073 PTPEEPTSPAAAVPTPEE---PTSPAAAVPTPEEPTSP 1107
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 60.5 bits (145), Expect = 5e-09
Identities = 66/241 (27%), Positives = 84/241 (34%), Gaps = 50/241 (20%)
Query: 258 PPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPP---PPKHGLPDVGLAAEDSKRD 314
PP P P+ P P + P S + P P PP PP GLP
Sbjct: 561 PPCPAPCPLQAPPSPLTTPPPETPSSIATPP-PQAPPALASPPLQGLPS----------P 609
Query: 315 PLCPRRAEPCPRVPATPRRMSDPPLSTMPTAPGLRKPPCFRESASPSPEPWTPGHGACST 374
PL P P P P ++ PPL P+ P P A+PSP+ +
Sbjct: 610 PLSPLATPP----PQAPPXLALPPLQAPPSPPA---SPPLSPLATPSPQ---------AP 653
Query: 375 SSAAIMATATSRNCDKLKSFHL--SPRGPPTSEPPPVPANKPKFLKIAEEDPPREAAMPG 432
++ A+ HL +P PP S P P + P ++ P A P
Sbjct: 654 NALAV---------------HLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPS 698
Query: 433 LFVPP--VAPRPPALKLPVPEAMARPAVLPRPEKPQLPHLQRSPPDGQSFRSFSFEKPRQ 490
L PP V P PPA P A P P P L + SPP + PR
Sbjct: 699 LAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPL-QVPPSPPASPPMSPSATPPPRV 757
Query: 491 P 491
P
Sbjct: 758 P 758
Score = 59.7 bits (143), Expect = 8e-09
Identities = 79/304 (25%), Positives = 103/304 (33%), Gaps = 45/304 (14%)
Query: 216 PVDISLSPYPTDNEDYEHDDEDDSYLEPDSPEPGRLEDALMHPPAYPP------PPVPTP 269
P LSP T + + P SP P A PPA PP PP P
Sbjct: 637 PASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAP 696
Query: 270 ---RKPAFSDMPRAHSFTSKGPGPLLPP-PPPKHGLPDVGLAAEDSKRDPLCPRRAEPCP 325
P P + P PP PP P + + P+ P A P P
Sbjct: 697 PSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSP-SATPPP 755
Query: 326 RVP----ATPRRMSDPPLSTMPTAPGLRKPPCFRES-------ASPSPEPWTPGHGACST 374
RVP A P ++ P +++P +P + PP + A PSP PG S
Sbjct: 756 RVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSP 815
Query: 375 SSAAIMATATSRNCDKLKSFHLSPRGPPTSEPPPVPANKPKFLKIAEEDPPREAAMPGLF 434
S+ S +SP P + PPV A L++ PP A P L
Sbjct: 816 SA----------------SLPMSPLATPPPQAPPVLA--APLLQV----PPSPPASPTLQ 853
Query: 435 VPPVAPRP-PALKLPVPEAMARPAVLPRPEKPQLPHLQRSPPDGQSFRSFSFEKPRQPSQ 493
P P P P + P A P P + P S PD S + P +
Sbjct: 854 APRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRG 913
Query: 494 ADTG 497
D+G
Sbjct: 914 YDSG 917
Score = 52.0 bits (123), Expect = 2e-06
Identities = 79/293 (26%), Positives = 104/293 (35%), Gaps = 29/293 (9%)
Query: 258 PPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPPKHGLPDVGLAAEDSKRDPLC 317
P A P PP PRK S HS T P P GL + S PL
Sbjct: 194 PSARPRPPTEGPRKSVSS--ASEHSTTEPSPAARRRPSAGG-GLQRPASRSLSSSATPLS 250
Query: 318 -PRRAEPCPR-VPATPRRMSDP-PLSTMPTAPGLRKPPCFRESASPSPEPWTPGHGACST 374
P R+ P R P P S P P P PP R+ A+P+ P + A +
Sbjct: 251 SPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPP--RKDAAPALGPLSSSPLATPS 308
Query: 375 SSAAIMATATSRNCDKLKSFHLSPRGPPTSEP----PPVPANKPKF--LKIAEEDPPREA 428
S + P PP + P PP P+ P L PP +A
Sbjct: 309 PSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQA 368
Query: 429 AMPGLFVPPVAPRPPALKLP---VPEAMARPAVLPRPEKPQLPHLQRS----PPDGQSFR 481
P + PP+ P +P VP ++ P++ P L LQ + P Q+
Sbjct: 369 P-PSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATH 427
Query: 482 SFSFEKPRQ-------PSQADTGGDDSDEDYEKVPLPNSVFVNTTESCEVERL 527
SF PRQ PS+ + DS + LP S + T+ S V L
Sbjct: 428 SFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPL 480
Score = 51.6 bits (122), Expect = 2e-06
Identities = 64/239 (26%), Positives = 83/239 (34%), Gaps = 49/239 (20%)
Query: 241 LEPDSPEPGRLEDALMHPPAY--PPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPP-- 296
+ P + P R+ L PP P PP P P P+A + P LP PP
Sbjct: 747 MSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPAS 806
Query: 297 --------PKHGLPDVGLAAEDSKRDPLCPR---RAEPCPRVPAT---PRRMSDP----- 337
P LP LA + P+ + P P T PRR P
Sbjct: 807 FPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTS 866
Query: 338 ---PLSTMPTAPGLRKPPCFRESASPSPEPWTPGHGACSTSSAAIMATATSRNCDKLKSF 394
P T+ APG PP R +S P GH + +TS+ ++L+ +
Sbjct: 867 VSGPRLTLALAPGPPPPPS-RSPSSTLSGPDLAGHSSSATSTP-----------EELRGY 914
Query: 395 HLSPRGPPTSEPPPVPANKPKFLKIAEEDPPREAAMPGLFVPPVAPR-PPALKLPVPEA 452
P G + PPP AE AA PP+A R P LP P A
Sbjct: 915 DSGPEGGAAASPPP----------DAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPA 963
Score = 47.8 bits (112), Expect = 3e-05
Identities = 73/271 (26%), Positives = 95/271 (35%), Gaps = 47/271 (17%)
Query: 241 LEPDSPEPGRLEDALMHPPAYPP---------PPVPTPRKPAFSDMPRA---HSFTSKGP 288
L P SP L PPA PP PP+ P P+ +P HS TS
Sbjct: 343 LAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAP--PSLQTIPPIQVPHSLTS--- 397
Query: 289 GPLLPPPPPKHGLPDVGLAAEDSKRDPLCPRRAEPCPRVPA-TPRRMSDP--PLSTMPTA 345
P L PP L L A S P P T ++ P P ST P +
Sbjct: 398 -PSLQAPPSPLALSS--LQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDS 454
Query: 346 PGLRKP------PCFRESASPSPEPWT------PGHGACSTSSAAIMATATSRNCDKLKS 393
P L+ P P + S SP+ P + P S +S + A +S L++
Sbjct: 455 PPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLET 514
Query: 394 FHLSPRGPPTSEPPPVPANKPKFLKIAE-EDPPREAAMPGLFVPPVAPRPPALKLPVPEA 452
S PP+ + PP P + PP + A L P + P P+ +A
Sbjct: 515 --QSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPL-QA 571
Query: 453 MARPAVLPRPE--------KPQLPHLQRSPP 475
P P PE PQ P SPP
Sbjct: 572 PPSPLTTPPPETPSSIATPPPQAPPALASPP 602
Score = 31.6 bits (70), Expect = 2.3
Identities = 39/141 (27%), Positives = 50/141 (35%), Gaps = 15/141 (10%)
Query: 243 PDSPEPGRLEDALMHPPAYPP--PPVPTPRKPAFSDMPRAHS----FTSKGPGPLLPPPP 296
P P L L+ P PP P + PR+P + S + PGP PPPP
Sbjct: 827 PPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGP--PPPP 884
Query: 297 ---PKHGL--PDVGLAAEDSKRDPLCPRRAEPCPRVPATPRRMSDPPLSTMPTAPGLR-- 349
P L PD+ + + P R + P A D L+ A R
Sbjct: 885 SRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGP 944
Query: 350 KPPCFRESASPSPEPWTPGHG 370
PP A +P PW P G
Sbjct: 945 APPLAFRGAPGAPLPWPPATG 965
Score = 30.0 bits (66), Expect = 6.6
Identities = 47/189 (24%), Positives = 57/189 (30%), Gaps = 42/189 (22%)
Query: 284 TSKGPGPLLPPPPPKHGLPDVGLAAEDSKRDPLCPRRA---------------------- 321
T + PG PPPP V AA R PL R
Sbjct: 26 TPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAGT 85
Query: 322 ---EPCPRVPATPRRMSDPPLSTMPTAPGLRKPPCFRESASPSPEPWTPGHGACSTSSAA 378
P R PA+ R PP T+PG P AS + P G S+
Sbjct: 86 SSRNPASRPPASGRGERAPPAKN--TSPG---PVSSPGRASGTTRPGPLGQKGLRISAEE 140
Query: 379 IMATATSRNCDKLKSFHLSPR----GPPTSEPPPVPANKPKFLKIAEEDPPREAAMPGLF 434
+A + K + R GP P P A + + E PR A
Sbjct: 141 TVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAG-TEVGLPRPA------ 193
Query: 435 VPPVAPRPP 443
P PRPP
Sbjct: 194 -PSARPRPP 201
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 59.7 bits (143), Expect = 8e-09
Identities = 73/260 (28%), Positives = 93/260 (35%), Gaps = 34/260 (13%)
Query: 241 LEPDSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGP-GPLLPPPP--- 296
L P SP L PPA PP T + HSF P PL PPP
Sbjct: 340 LAPPSPSAPPSLQTLPSPPATPPSQATTSL--GSPTLQATHSFLPSPPLSPLATPPPQAP 397
Query: 297 PKHGLPDVGLAAEDSKRDPLCPRRAEPCPRVP-ATPRRMSDPPLSTMPTAPGLRKPPCFR 355
P LP + PL P A P P+ P A + P S P+ PP
Sbjct: 398 PALALPPLQAPPSPPASPPLSPL-ATPSPQAPNALAVHLLQAPFSPPPS------PPVQA 450
Query: 356 ESASPSPEPWTPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSE-PPPVPANKP 414
+ P+ P +P S + ++ A S +SP P + PPP+ A
Sbjct: 451 PFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPL 510
Query: 415 KFLKIAEEDPPREAAMP--GLFVPPV-----APRPPALKLPV----------PEAMARPA 457
+ K + PP A P L PP AP P+ LP+ P +A P
Sbjct: 511 QLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPL 570
Query: 458 VLPRPEKPQLPHLQ--RSPP 475
+ P P P LQ R PP
Sbjct: 571 LQVPPSPPASPTLQAPRRPP 590
Score = 59.3 bits (142), Expect = 1e-08
Identities = 68/265 (25%), Positives = 92/265 (34%), Gaps = 48/265 (18%)
Query: 243 PDSPEPGRLEDALMHPPAYPPP--------------PVPTPRK---------PAFSDMPR 279
P P+P L+ + PP PP P+ TP P P
Sbjct: 269 PSQPKPKGLQ--ALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPH 326
Query: 280 AHSFTSKGPGPLLPPPPPKHGLPDVGLAAEDSKRDPLCPRRAEPCPRVPATPRRMSDPPL 339
+ S T + PL PP P + P + P + AT + PPL
Sbjct: 327 SSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPL 386
Query: 340 STMPTAP-----GLRKPPCFRESASPSPEPWTPGHGACSTSSAAIMATATSRNCDKLKSF 394
S + T P L PP + P+ P +P +AT + + + L +
Sbjct: 387 SPLATPPPQAPPALALPPLQAPPSPPASPPLSP------------LATPSPQAPNAL-AV 433
Query: 395 HL--SPRGPPTSEPPPVPANKPKFLKIAEEDPPREAAMPGLFVPP--VAPRPPALKLPVP 450
HL +P PP S P P + P ++ P A P L PP V P PPA P
Sbjct: 434 HLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSP 493
Query: 451 EAMARPAVLPRPEKPQLPHLQRSPP 475
A P P P L L + PP
Sbjct: 494 SATPPPQAPPPLAAPPL-QLAKPPP 517
Score = 55.5 bits (132), Expect = 1e-07
Identities = 64/232 (27%), Positives = 80/232 (34%), Gaps = 53/232 (22%)
Query: 255 LMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPP---PPPKHGLPDVGLAAED- 310
L P P TPR PA P+ KG L PP PP K P +G +
Sbjct: 249 LSSPARSGPSARGTPRAPAHPSQPK-----PKGLQALRPPQVTPPRKDAAPALGPLSSSP 303
Query: 311 -SKRDPLCPRRAEPCPRVPATPRRMS-----DPPLSTMPTAPGLRKPPCFRESASPSPEP 364
+ P +++ P +PATP S PL P +P PP + PSP
Sbjct: 304 LATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPS--APPSLQ--TLPSPPA 359
Query: 365 WTPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSEPPPVPANKPKFLKIAEEDP 424
P S S + AT SF SP P + PPP
Sbjct: 360 TPPSQATTSLGSPTLQAT---------HSFLPSPPLSPLATPPP--------------QA 396
Query: 425 PREAAMPGLFVPPVAPRPPALKLPVPEAMARPAVLPRPEKPQ--LPHLQRSP 474
P A+P L PP P P L P P P+ P HL ++P
Sbjct: 397 PPALALPPLQAPPSPPASPPLS---------PLATPSPQAPNALAVHLLQAP 439
Score = 47.4 bits (111), Expect = 4e-05
Identities = 63/238 (26%), Positives = 81/238 (34%), Gaps = 53/238 (22%)
Query: 243 PDSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPP------ 296
P SP PP PPP+ P P+A + P LP PP
Sbjct: 482 PPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQ 541
Query: 297 ----PKHGLPDVGLAAEDSKRDPLCPRRAEPCPRVPAT---------PRRMSDP------ 337
P LP LA + P+ A P +VP + PRR P
Sbjct: 542 APFSPSASLPMSPLATPPPQAPPVL---AAPLLQVPPSPPASPTLQAPRRPPTPGPDTSV 598
Query: 338 --PLSTMPTAPGLRKPPCFRESASPSPEPWTPGHGACSTSSAAIMATATSRNCDKLKSFH 395
P T+ APG PP R +S P GH + +TS+ ++L+ +
Sbjct: 599 SGPRLTLALAPGPPPPPS-RSPSSTLSGPDLAGHSSSATSTP-----------EELRGYD 646
Query: 396 LSPRGPPTSEPPPVPANKPKFLKIAEEDPPREAAMPGLFVPPVAPR-PPALKLPVPEA 452
P G + PPP AE AA PP+A R P LP P A
Sbjct: 647 SGPEGGAAASPPP----------DAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPA 694
Score = 31.6 bits (70), Expect = 2.3
Identities = 39/141 (27%), Positives = 50/141 (35%), Gaps = 15/141 (10%)
Query: 243 PDSPEPGRLEDALMHPPAYPP--PPVPTPRKPAFSDMPRAHS----FTSKGPGPLLPPPP 296
P P L L+ P PP P + PR+P + S + PGP PPPP
Sbjct: 558 PPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGP--PPPP 615
Query: 297 ---PKHGL--PDVGLAAEDSKRDPLCPRRAEPCPRVPATPRRMSDPPLSTMPTAPGLR-- 349
P L PD+ + + P R + P A D L+ A R
Sbjct: 616 SRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGP 675
Query: 350 KPPCFRESASPSPEPWTPGHG 370
PP A +P PW P G
Sbjct: 676 APPLAFRGAPGAPLPWPPATG 696
Score = 30.0 bits (66), Expect = 6.6
Identities = 47/189 (24%), Positives = 57/189 (30%), Gaps = 42/189 (22%)
Query: 284 TSKGPGPLLPPPPPKHGLPDVGLAAEDSKRDPLCPRRA---------------------- 321
T + PG PPPP V AA R PL R
Sbjct: 26 TPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAGT 85
Query: 322 ---EPCPRVPATPRRMSDPPLSTMPTAPGLRKPPCFRESASPSPEPWTPGHGACSTSSAA 378
P R PA+ R PP T+PG P AS + P G S+
Sbjct: 86 SSRNPASRPPASGRGERAPPAKN--TSPG---PVSSPGRASGTTRPGPLGQKGLRISAEE 140
Query: 379 IMATATSRNCDKLKSFHLSPR----GPPTSEPPPVPANKPKFLKIAEEDPPREAAMPGLF 434
+A + K + R GP P P A + + E PR A
Sbjct: 141 TVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAG-TEVGLPRPA------ 193
Query: 435 VPPVAPRPP 443
P PRPP
Sbjct: 194 -PSARPRPP 201
>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 59.7 bits (143), Expect = 8e-09
Identities = 66/243 (27%), Positives = 88/243 (36%), Gaps = 38/243 (15%)
Query: 258 PPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPPKHGL-----PDVGLAAEDSK 312
PP PP T KP FS F PG PP P+ PDVG SK
Sbjct: 126 PPLLPPGGRSTSAKP-FSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVG-----SK 179
Query: 313 RDPLCPRRAEPCPRVPATPRRMSDPPLST-MPTAPGLRKPPCFRESASPSPEPWTPGHGA 371
D + P VP+TPR + P + P PG + P S P+P P+ PG+
Sbjct: 180 PDSIPPP-------VPSTPRPIQSSPHNRGSPPVPGGPRQP----SPGPTPPPF-PGNRG 227
Query: 372 CSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSEPPPVPANKPKFLKIAEEDPPREAA-M 430
+ +I + S + P S PP+P + L PP
Sbjct: 228 TALGGGSIRQSPLSSSS-------------PFSNRPPLPPTPSRALDDKPPPPPPPVGNR 274
Query: 431 PGLFVPPVAPRPPALKLPVPEAMARPAVLPRPEKPQLPHLQRSPPDGQSFRSFSFEKPRQ 490
P + V P PP P + RP+ + P P + PP S + E PR
Sbjct: 275 PSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRL 334
Query: 491 PSQ 493
P +
Sbjct: 335 PQR 337
Score = 52.0 bits (123), Expect = 2e-06
Identities = 79/316 (25%), Positives = 101/316 (31%), Gaps = 63/316 (19%)
Query: 223 PYPTDNEDYEHDDEDDSYLEPDSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHS 282
P P+ + + + P P+ G D++ PPPVP+ +P S S
Sbjct: 151 PVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSI-------PPPVPSTPRPIQSSPHNRGS 203
Query: 283 FTSKG------PGPLLPPPPPKHGLP---------DVGLAAEDSKRDPL--CPRRA---E 322
G PGP PP P G + ++ S R PL P RA +
Sbjct: 204 PPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDK 263
Query: 323 PCPRVPATPRRMS--------DPPLSTMPTAPGLRKPPCFRESASPSPEPWTPGHGACST 374
P P P R S PP + P P +P ++ P P P PG
Sbjct: 264 PPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPP 323
Query: 375 SSAAIMATAT--SRNCDKLKSF-------HLSPRGPPTSEPPPVPANKPKFLKIAEEDPP 425
SS+ T RN S P PP SE PP P P PP
Sbjct: 324 SSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPP 383
Query: 426 -------REAAMP---------GLFVPPVAPRPPALKLPVPEAMARPAVLPRPEKPQLPH 469
A+P G+ P PRPP LP A P P
Sbjct: 384 PVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPP---LPPDRPSAGAPPPPPPSTSIRNG 440
Query: 470 LQRSPPDGQSFRSFSF 485
Q SP + + F F
Sbjct: 441 FQDSPCEDEWESRFYF 456
Score = 38.5 bits (88), Expect = 0.018
Identities = 42/142 (29%), Positives = 47/142 (33%), Gaps = 38/142 (26%)
Query: 243 PDSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPPKHGLP 302
P P PGR P PPPPV P P S GPL PPPP
Sbjct: 346 PPLPSPGRSGPLPPPPSERPPPPVRDP--PGRS-------------GPLPPPPPVSRN-- 388
Query: 303 DVGLAAEDSKRDPLCPRRA-----EPCPRVPATPRRMS----DPPLSTMPTAPGLRKPPC 353
G + P P R+ PR P P R S PP + G + PC
Sbjct: 389 --GSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPPPPPSTSIRNGFQDSPC 446
Query: 354 FRE----------SASPSPEPW 365
E S P PEP+
Sbjct: 447 EDEWESRFYFHPISDLPPPEPY 468
>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 59.7 bits (143), Expect = 8e-09
Identities = 66/243 (27%), Positives = 88/243 (36%), Gaps = 38/243 (15%)
Query: 258 PPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPPKHGL-----PDVGLAAEDSK 312
PP PP T KP FS F PG PP P+ PDVG SK
Sbjct: 126 PPLLPPGGRSTSAKP-FSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVG-----SK 179
Query: 313 RDPLCPRRAEPCPRVPATPRRMSDPPLST-MPTAPGLRKPPCFRESASPSPEPWTPGHGA 371
D + P VP+TPR + P + P PG + P S P+P P+ PG+
Sbjct: 180 PDSIPPP-------VPSTPRPIQSSPHNRGSPPVPGGPRQP----SPGPTPPPF-PGNRG 227
Query: 372 CSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSEPPPVPANKPKFLKIAEEDPPREAA-M 430
+ +I + S + P S PP+P + L PP
Sbjct: 228 TALGGGSIRQSPLSSSS-------------PFSNRPPLPPTPSRALDDKPPPPPPPVGNR 274
Query: 431 PGLFVPPVAPRPPALKLPVPEAMARPAVLPRPEKPQLPHLQRSPPDGQSFRSFSFEKPRQ 490
P + V P PP P + RP+ + P P + PP S + E PR
Sbjct: 275 PSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRL 334
Query: 491 PSQ 493
P +
Sbjct: 335 PQR 337
Score = 52.0 bits (123), Expect = 2e-06
Identities = 79/316 (25%), Positives = 101/316 (31%), Gaps = 63/316 (19%)
Query: 223 PYPTDNEDYEHDDEDDSYLEPDSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHS 282
P P+ + + + P P+ G D++ PPPVP+ +P S S
Sbjct: 151 PVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSI-------PPPVPSTPRPIQSSPHNRGS 203
Query: 283 FTSKG------PGPLLPPPPPKHGLP---------DVGLAAEDSKRDPL--CPRRA---E 322
G PGP PP P G + ++ S R PL P RA +
Sbjct: 204 PPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDK 263
Query: 323 PCPRVPATPRRMS--------DPPLSTMPTAPGLRKPPCFRESASPSPEPWTPGHGACST 374
P P P R S PP + P P +P ++ P P P PG
Sbjct: 264 PPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPP 323
Query: 375 SSAAIMATAT--SRNCDKLKSF-------HLSPRGPPTSEPPPVPANKPKFLKIAEEDPP 425
SS+ T RN S P PP SE PP P P PP
Sbjct: 324 SSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPP 383
Query: 426 -------REAAMP---------GLFVPPVAPRPPALKLPVPEAMARPAVLPRPEKPQLPH 469
A+P G+ P PRPP LP A P P
Sbjct: 384 PVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPP---LPPDRPSAGAPPPPPPSTSIRNG 440
Query: 470 LQRSPPDGQSFRSFSF 485
Q SP + + F F
Sbjct: 441 FQDSPCEDEWESRFYF 456
Score = 38.5 bits (88), Expect = 0.018
Identities = 42/142 (29%), Positives = 47/142 (33%), Gaps = 38/142 (26%)
Query: 243 PDSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPPKHGLP 302
P P PGR P PPPPV P P S GPL PPPP
Sbjct: 346 PPLPSPGRSGPLPPPPSERPPPPVRDP--PGRS-------------GPLPPPPPVSRN-- 388
Query: 303 DVGLAAEDSKRDPLCPRRA-----EPCPRVPATPRRMS----DPPLSTMPTAPGLRKPPC 353
G + P P R+ PR P P R S PP + G + PC
Sbjct: 389 --GSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPPPPPSTSIRNGFQDSPC 446
Query: 354 FRE----------SASPSPEPW 365
E S P PEP+
Sbjct: 447 EDEWESRFYFHPISDLPPPEPY 468
>gi|41281612 zinc finger protein 828 [Homo sapiens]
Length = 812
Score = 59.7 bits (143), Expect = 8e-09
Identities = 74/260 (28%), Positives = 94/260 (36%), Gaps = 64/260 (24%)
Query: 239 SYLEPDSPEPGRLED-------ALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPL 291
S L P+SP+P L +++ P P P P P KPA +
Sbjct: 139 SVLSPESPKPTPLTPLEPQKPGSVVSPELQTPLPSPEPSKPA----------------SV 182
Query: 292 LPPPPPKHGLPDVGLAAEDSKRDPL-CPRRAEPCPRVPATPR-RMSDPPLSTMPTAPGLR 349
P PPK +P E K P+ P +P P P + + +S+P P
Sbjct: 183 SSPEPPK-SVP----VCESQKLAPVPSPEPQKPAPVSPESVKATLSNPKPQKQSHFPETL 237
Query: 350 KPPCFRESASP----SPEPWTPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSE 405
PP SP SPEPW P A S + T+ PR P SE
Sbjct: 238 GPPSASSPESPVLAASPEPWGPSPAASPESRKSARTTSP------------EPRKPSPSE 285
Query: 406 PP----PVPANKPKFLKIAEEDPPREAAMPGLFV--PPVAPR-----PPALKLPVPEAMA 454
P P PA P E P A PG + PP +PR P A P A
Sbjct: 286 SPEPWKPFPAVSP------EPRRPAPAVSPGSWKPGPPGSPRPWKSNPSASSGPWKPAKP 339
Query: 455 RPAVLPRPEKPQLPHLQRSP 474
P+V P P KP +P + P
Sbjct: 340 APSVSPGPWKP-IPSVSPGP 358
Score = 52.0 bits (123), Expect = 2e-06
Identities = 68/260 (26%), Positives = 89/260 (34%), Gaps = 32/260 (12%)
Query: 258 PPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPPKHGLPDVGLAAEDSKRDPL- 316
P PP +P P + P GP P P K + E K P
Sbjct: 234 PETLGPPSASSPESPVLAASPEPW-----GPSPAASPESRKSARTT---SPEPRKPSPSE 285
Query: 317 CPRRAEPCPRVPATPRRMSDP--PLSTMPTAPGLRKPPCFRESASPSPEPWTPGHGACST 374
P +P P V PRR + P S P PG +P ++ + S S PW P A S
Sbjct: 286 SPEPWKPFPAVSPEPRRPAPAVSPGSWKPGPPGSPRP--WKSNPSASSGPWKPAKPAPSV 343
Query: 375 S----------SAAIMATATSRNCDKLKSFHLSP---RGPPTSEPPPVPANKPKFLKIAE 421
S S S + KS +SP + PP S P + P+ K A
Sbjct: 344 SPGPWKPIPSVSPGPWKPTPSVSSASWKSSSVSPSSWKSPPAS-PESWKSGPPELRKTAP 402
Query: 422 EDPPREAAMPGLFVPPVAPRPPALKLPVPEAMARPAVLPRPEKPQ-LPHLQRSPPDGQSF 480
P VPPV+P P+ + PA P KP P L + PD +
Sbjct: 403 TLSPEHWKA----VPPVSPELRKPGPPLSPEIRSPAGSPELRKPSGSPDLWKLSPDQRKT 458
Query: 481 RSFSFEKPRQPSQADTGGDD 500
S + P + G D
Sbjct: 459 SPASLDFPESQKSSRGGSPD 478
Score = 42.0 bits (97), Expect = 0.002
Identities = 57/236 (24%), Positives = 89/236 (37%), Gaps = 47/236 (19%)
Query: 285 SKGPGPLLPPPPPKH-----------GLPDVGLAAEDSKRDPLCPRRAEPCPRVPATPRR 333
+K P+ PP P+H +P + + + L P +P P P P++
Sbjct: 100 NKETDPVKSPPLPEHQKIPCNSAEPKSIPALSMETQ-KLGSVLSPESPKPTPLTPLEPQK 158
Query: 334 MSDPPLSTMPTAPGLRKPPCFRESASPSPEPWTPGHGACSTSSAAIMATATSRNCDKLKS 393
P S + +P L+ P PSPEP P A++ + ++ +S
Sbjct: 159 ----PGSVV--SPELQTP-------LPSPEPSKP---------ASVSSPEPPKSVPVCES 196
Query: 394 FHLSP-RGPPTSEPPPVPANKPKFLKIAEEDPPREAAMPGLFVPPVA--PRPPALKLPVP 450
L+P P +P PV K ++ P +++ P PP A P P L
Sbjct: 197 QKLAPVPSPEPQKPAPVSPESVK-ATLSNPKPQKQSHFPETLGPPSASSPESPVLAASPE 255
Query: 451 EAMARPAVLPRPEK--------PQLPHLQRSPPDGQSFRSFSFEKPRQPSQADTGG 498
PA P K P+ P SP + F + S E PR+P+ A + G
Sbjct: 256 PWGPSPAASPESRKSARTTSPEPRKPSPSESPEPWKPFPAVSPE-PRRPAPAVSPG 310
>gi|56549666 tyrosine kinase, non-receptor, 2 isoform 1 [Homo
sapiens]
Length = 1038
Score = 59.3 bits (142), Expect = 1e-08
Identities = 66/220 (30%), Positives = 82/220 (37%), Gaps = 44/220 (20%)
Query: 245 SPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPPKHGLPDV 304
SP PG +D PP P PP PT S P TS+ PGP PP P
Sbjct: 728 SPSPGG-DDKPQVPPRVPIPPRPTRPHVQLSPAPPGEEETSQWPGPASPPRVP------- 779
Query: 305 GLAAEDSKRDPLCPRRAE-PCPRVP----ATPRRMSDPPLSTMPTAPGLRKPPCFRESAS 359
R+PL P+ + P P VP P R+S P TMPT +S +
Sbjct: 780 -------PREPLSPQGSRTPSPLVPPGSSPLPPRLSSSPGKTMPTT----------QSFA 822
Query: 360 PSPEPWTPGHGACSTSSAAIMATATSRNCDKLKSFH--LSPRGPPTSEPPPVPANKPKFL 417
P+ TP A R+ K+ S H L P P E +FL
Sbjct: 823 SDPKYATPQVIQAPGPRAGPCILPIVRDGKKVSSTHYYLLPERPSYLE------RYQRFL 876
Query: 418 KIAEE-DPPREAAMPGLFVPPVAPRPPALKLPVPEAMARP 456
+ A+ + P +P L PP P P A P A RP
Sbjct: 877 REAQSPEEPTPLPVPLLLPPPSTPAPAA-----PTATVRP 911
Score = 37.0 bits (84), Expect = 0.054
Identities = 72/304 (23%), Positives = 102/304 (33%), Gaps = 51/304 (16%)
Query: 196 PLDTSD------SSSDTDSFYGAVERPVDISLSPYPTDNEDYEHDDEDDSYLEPDSPEPG 249
P+D D S+S G V++P Y+ ED L D G
Sbjct: 490 PMDPPDLLSVELSTSRPPQHLGGVKKPT-------------YDPVSEDQDPLSSDFKRLG 536
Query: 250 RLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPPKHGLPDVGLAAE 309
+ L P P A + G P++P P P + A
Sbjct: 537 LRKPGLPRGLWLAKPSARVPGTKASRGSGAEVTLIDFGEEPVVPALRPC--APSLAQLAM 594
Query: 310 DSKRDPLCPRRAEPCPRVP--ATPRRMSDPPLSTMPTAPGLRKPPCFRESASPSPEPWTP 367
D+ C E P+ P A PR + P+ P L PP + + A +
Sbjct: 595 DA-----CSLLDETPPQSPTRALPRPLHPTPVVDWDARP-LPPPPAYDDVAQDEDD---- 644
Query: 368 GHGACSTSSAAIMATATSRNCDKLKSFHLSP---RGPPTSE-----PPPVPANKPKFLKI 419
CS +S + A + ++ P R PP E PP P +
Sbjct: 645 -FEICSINSTLVGAGVPAGPSQGQTNYAFVPEQARPPPPLEDNLFLPPQGGGKPPSSAQT 703
Query: 420 AEE-DPPREAAMPGLFVPPVAPRPPALKLPVPEAMARPAVLPR---PEKPQLPHLQRSP- 474
AE ++ M L P +P P P P +P V PR P +P PH+Q SP
Sbjct: 704 AEIFQALQQECMRQLQAPAGSPAPS----PSPGGDDKPQVPPRVPIPPRPTRPHVQLSPA 759
Query: 475 PDGQ 478
P G+
Sbjct: 760 PPGE 763
Score = 31.2 bits (69), Expect = 3.0
Identities = 63/289 (21%), Positives = 98/289 (33%), Gaps = 50/289 (17%)
Query: 259 PAYPPPPV-----PTPRKPAFSDMPRAH--------SFTSKGPGPLLPPPPPKHGLPDVG 305
P +P P V P P PA+ D+ + + T G G P P G +
Sbjct: 615 PLHPTPVVDWDARPLPPPPAYDDVAQDEDDFEICSINSTLVGAGV---PAGPSQGQTNYA 671
Query: 306 LAAEDSKRDPLCPRRAEPCPRVPATPRRMSDPPLSTMPTAPGLR--KPPCFRESASP--S 361
E ++ P P P + P S+ TA + + C R+ +P S
Sbjct: 672 FVPEQARPPP-------PLEDNLFLPPQGGGKPPSSAQTAEIFQALQQECMRQLQAPAGS 724
Query: 362 PEPWTPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSEPPPVPANKPKFLKIAE 421
P P +P G R +P G + P PA+ P+ +
Sbjct: 725 PAP-SPSPGGDDKPQVPPRVPIPPRPTRPHVQLSPAPPGEEETSQWPGPASPPR---VPP 780
Query: 422 EDP--PREAAMPGLFVPP-VAPRPPALK------LPVPEAMARPAVLPRPEKPQLPHLQR 472
+P P+ + P VPP +P PP L +P ++ A P+ Q P +
Sbjct: 781 REPLSPQGSRTPSPLVPPGSSPLPPRLSSSPGKTMPTTQSFASDPKYATPQVIQAPGPRA 840
Query: 473 SP------PDGQSFRSFSF----EKPRQPSQADTGGDDSDEDYEKVPLP 511
P DG+ S + E+P + ++ E PLP
Sbjct: 841 GPCILPIVRDGKKVSSTHYYLLPERPSYLERYQRFLREAQSPEEPTPLP 889
Score = 31.2 bits (69), Expect = 3.0
Identities = 22/67 (32%), Positives = 27/67 (40%), Gaps = 5/67 (7%)
Query: 243 PDSPEPGRLEDALMHPPAYPPPPVPT----PRKPAFSDMPRAHSFTSKGPGPLLPPPPPK 298
P+ P P + L+ PP+ P P PT P A D S + PG PPP
Sbjct: 882 PEEPTPLPVP-LLLPPPSTPAPAAPTATVRPMPQAALDPKANFSTNNSNPGARPPPPRAT 940
Query: 299 HGLPDVG 305
LP G
Sbjct: 941 ARLPQRG 947
Score = 30.8 bits (68), Expect = 3.9
Identities = 46/177 (25%), Positives = 62/177 (35%), Gaps = 31/177 (17%)
Query: 242 EPDSPEPGRLEDALMHPPAYPPPP--VPTPRKPAFSDMPRAHSFTSK---GPGPLLPPPP 296
EP SP+ R L+ P + P PP +P K MP SF S ++ P
Sbjct: 782 EPLSPQGSRTPSPLVPPGSSPLPPRLSSSPGK----TMPTTQSFASDPKYATPQVIQAPG 837
Query: 297 PKHGLPDVGLAAEDSKRDP-----LCPRRAEPCPRVPATPRRMSDPPLSTMPTAPGLRKP 351
P+ G P + D K+ L P R R R P T P L P
Sbjct: 838 PRAG-PCILPIVRDGKKVSSTHYYLLPERPSYLERYQRFLREAQSPEEPTPLPVPLLLPP 896
Query: 352 PCFRESASPSPEPWTPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSEPPP 408
P ++P+P A T++ M A D +F + P PPP
Sbjct: 897 P-----STPAP--------AAPTATVRPMPQAA---LDPKANFSTNNSNPGARPPPP 937
>gi|58331191 tyrosine kinase, non-receptor, 2 isoform 2 [Homo
sapiens]
Length = 1086
Score = 59.3 bits (142), Expect = 1e-08
Identities = 66/220 (30%), Positives = 82/220 (37%), Gaps = 44/220 (20%)
Query: 245 SPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPPKHGLPDV 304
SP PG +D PP P PP PT S P TS+ PGP PP P
Sbjct: 806 SPSPGG-DDKPQVPPRVPIPPRPTRPHVQLSPAPPGEEETSQWPGPASPPRVP------- 857
Query: 305 GLAAEDSKRDPLCPRRAE-PCPRVP----ATPRRMSDPPLSTMPTAPGLRKPPCFRESAS 359
R+PL P+ + P P VP P R+S P TMPT +S +
Sbjct: 858 -------PREPLSPQGSRTPSPLVPPGSSPLPPRLSSSPGKTMPTT----------QSFA 900
Query: 360 PSPEPWTPGHGACSTSSAAIMATATSRNCDKLKSFH--LSPRGPPTSEPPPVPANKPKFL 417
P+ TP A R+ K+ S H L P P E +FL
Sbjct: 901 SDPKYATPQVIQAPGPRAGPCILPIVRDGKKVSSTHYYLLPERPSYLE------RYQRFL 954
Query: 418 KIAEE-DPPREAAMPGLFVPPVAPRPPALKLPVPEAMARP 456
+ A+ + P +P L PP P P A P A RP
Sbjct: 955 REAQSPEEPTPLPVPLLLPPPSTPAPAA-----PTATVRP 989
Score = 38.5 bits (88), Expect = 0.018
Identities = 74/306 (24%), Positives = 104/306 (33%), Gaps = 40/306 (13%)
Query: 196 PLDTSD------SSSDTDSFYGAVER--PVDISLSPYPTDNEDYEHDDEDDSYLEPDSPE 247
P+D D S+S G V+R P + T Y+ ED L D
Sbjct: 553 PMDPPDLLSVELSTSRPPQHLGGVKREPPPRPPQPAFFTQKPTYDPVSEDQDPLSSDFKR 612
Query: 248 PGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPPKHGLPDVGLA 307
G + L P P A + G P++P P P +
Sbjct: 613 LGLRKPGLPRGLWLAKPSARVPGTKASRGSGAEVTLIDFGEEPVVPALRPC--APSLAQL 670
Query: 308 AEDSKRDPLCPRRAEPCPRVP--ATPRRMSDPPLSTMPTAPGLRKPPCFRESASPSPEPW 365
A D+ C E P+ P A PR + P+ P L PP + + A +
Sbjct: 671 AMDA-----CSLLDETPPQSPTRALPRPLHPTPVVDWDARP-LPPPPAYDDVAQDEDD-- 722
Query: 366 TPGHGACSTSSAAIMATATSRNCDKLKSFHLSP---RGPPTSE-----PPPVPANKPKFL 417
CS +S + A + ++ P R PP E PP P
Sbjct: 723 ---FEICSINSTLVGAGVPAGPSQGQTNYAFVPEQARPPPPLEDNLFLPPQGGGKPPSSA 779
Query: 418 KIAEE-DPPREAAMPGLFVPPVAPRPPALKLPVPEAMARPAVLPR---PEKPQLPHLQRS 473
+ AE ++ M L P +P P P P +P V PR P +P PH+Q S
Sbjct: 780 QTAEIFQALQQECMRQLQAPAGSPAPS----PSPGGDDKPQVPPRVPIPPRPTRPHVQLS 835
Query: 474 P-PDGQ 478
P P G+
Sbjct: 836 PAPPGE 841
Score = 31.2 bits (69), Expect = 3.0
Identities = 63/289 (21%), Positives = 98/289 (33%), Gaps = 50/289 (17%)
Query: 259 PAYPPPPV-----PTPRKPAFSDMPRAH--------SFTSKGPGPLLPPPPPKHGLPDVG 305
P +P P V P P PA+ D+ + + T G G P P G +
Sbjct: 693 PLHPTPVVDWDARPLPPPPAYDDVAQDEDDFEICSINSTLVGAGV---PAGPSQGQTNYA 749
Query: 306 LAAEDSKRDPLCPRRAEPCPRVPATPRRMSDPPLSTMPTAPGLR--KPPCFRESASP--S 361
E ++ P P P + P S+ TA + + C R+ +P S
Sbjct: 750 FVPEQARPPP-------PLEDNLFLPPQGGGKPPSSAQTAEIFQALQQECMRQLQAPAGS 802
Query: 362 PEPWTPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSEPPPVPANKPKFLKIAE 421
P P +P G R +P G + P PA+ P+ +
Sbjct: 803 PAP-SPSPGGDDKPQVPPRVPIPPRPTRPHVQLSPAPPGEEETSQWPGPASPPR---VPP 858
Query: 422 EDP--PREAAMPGLFVPP-VAPRPPALK------LPVPEAMARPAVLPRPEKPQLPHLQR 472
+P P+ + P VPP +P PP L +P ++ A P+ Q P +
Sbjct: 859 REPLSPQGSRTPSPLVPPGSSPLPPRLSSSPGKTMPTTQSFASDPKYATPQVIQAPGPRA 918
Query: 473 SP------PDGQSFRSFSF----EKPRQPSQADTGGDDSDEDYEKVPLP 511
P DG+ S + E+P + ++ E PLP
Sbjct: 919 GPCILPIVRDGKKVSSTHYYLLPERPSYLERYQRFLREAQSPEEPTPLP 967
Score = 31.2 bits (69), Expect = 3.0
Identities = 22/67 (32%), Positives = 27/67 (40%), Gaps = 5/67 (7%)
Query: 243 PDSPEPGRLEDALMHPPAYPPPPVPT----PRKPAFSDMPRAHSFTSKGPGPLLPPPPPK 298
P+ P P + L+ PP+ P P PT P A D S + PG PPP
Sbjct: 960 PEEPTPLPVP-LLLPPPSTPAPAAPTATVRPMPQAALDPKANFSTNNSNPGARPPPPRAT 1018
Query: 299 HGLPDVG 305
LP G
Sbjct: 1019 ARLPQRG 1025
Score = 30.8 bits (68), Expect = 3.9
Identities = 46/177 (25%), Positives = 62/177 (35%), Gaps = 31/177 (17%)
Query: 242 EPDSPEPGRLEDALMHPPAYPPPP--VPTPRKPAFSDMPRAHSFTSK---GPGPLLPPPP 296
EP SP+ R L+ P + P PP +P K MP SF S ++ P
Sbjct: 860 EPLSPQGSRTPSPLVPPGSSPLPPRLSSSPGK----TMPTTQSFASDPKYATPQVIQAPG 915
Query: 297 PKHGLPDVGLAAEDSKRDP-----LCPRRAEPCPRVPATPRRMSDPPLSTMPTAPGLRKP 351
P+ G P + D K+ L P R R R P T P L P
Sbjct: 916 PRAG-PCILPIVRDGKKVSSTHYYLLPERPSYLERYQRFLREAQSPEEPTPLPVPLLLPP 974
Query: 352 PCFRESASPSPEPWTPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSEPPP 408
P ++P+P A T++ M A D +F + P PPP
Sbjct: 975 P-----STPAP--------AAPTATVRPMPQAA---LDPKANFSTNNSNPGARPPPP 1015
>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
tract binding protein associated) [Homo sapiens]
Length = 707
Score = 58.9 bits (141), Expect = 1e-08
Identities = 69/253 (27%), Positives = 85/253 (33%), Gaps = 53/253 (20%)
Query: 242 EPDSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPPKHGL 301
+P P P + PP PPP P P +P P PPPPP
Sbjct: 57 KPPIPPPPPHQQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQ---------QPPPPP---- 103
Query: 302 PDVGLAAEDSKRDPLCPRRAEPCPRVPATPRRMSDPPLSTMPTAPGLRKPPCFRESASPS 361
+DS + P+ + P P V + P S P +T PT+ PP + P
Sbjct: 104 -------QDSSK-PVVAQGPGPAPGVGSAPPASSSAPPATPPTSGA---PP----GSGPG 148
Query: 362 PEPWTPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSEPPPVPANK-------P 414
P P TP S A T S P PP + P P P K P
Sbjct: 149 PTP-TPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGPGPGPKQGPGPGGP 207
Query: 415 KFLKIAEEDPPREAAMPGLFVPPVAPRPPALKLPVPEAMARPAVLPRPEKPQLP-----H 469
K K+ P+ PGL P P+PP R PR + P H
Sbjct: 208 KGGKM--PGGPKPGGGPGLSTPGGHPKPP----------HRGGGEPRGGRQHHPPYHQQH 255
Query: 470 LQRSPPDGQSFRS 482
Q PP G RS
Sbjct: 256 HQGPPPGGPGGRS 268
Score = 40.0 bits (92), Expect = 0.006
Identities = 47/194 (24%), Positives = 59/194 (30%), Gaps = 19/194 (9%)
Query: 295 PPPKHGLPDVGLAAEDSKRDPLCPRRAEPCPRVPATPRRMSDPPLSTMPTAPGLRKPPCF 354
PPP GL + R P+ P + P+ P P P P ++PP
Sbjct: 34 PPPGMGL--------NQNRGPMGPGPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPPH 85
Query: 355 RESASPSP----EPWTPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSEPP--- 407
+ P P +P P + A A S P PPTS P
Sbjct: 86 QPPPHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPGS 145
Query: 408 ---PVPANKPKFLKIAEEDPPREAAMPGL-FVPPVAPRPPALKLPVPEAMARPAVLPRPE 463
P P P PP G+ PP A PP VP P P P
Sbjct: 146 GPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGPGPGPKQGPGPG 205
Query: 464 KPQLPHLQRSPPDG 477
P+ + P G
Sbjct: 206 GPKGGKMPGGPKPG 219
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 58.2 bits (139), Expect = 2e-08
Identities = 62/258 (24%), Positives = 106/258 (41%), Gaps = 34/258 (13%)
Query: 242 EPDSPEPGRLEDALMHPPAYPPPPVPTPRKPAFS-----DMPRAHSFTSKGPGPLLP--- 293
+P++P P ++ +A PVP P+KP ++P+A K P + P
Sbjct: 10517 KPEAPPP-KVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKAAVPEKKVPEAIPPKPE 10575
Query: 294 -PPP-----PKHGLPDVGLAAEDSKRD-------PLCPRRAEPCPRVPATPRRMSDPPLS 340
PPP PK +P+ + A K+ P P+ P +VP P + + P +
Sbjct: 10576 SPPPEVPEAPKEVVPEKKVPAAPPKKPEVTPVKVPEAPKEVVPEKKVPVPPPKKPEVPPT 10635
Query: 341 TMPTAPGLRKPPCFRESASPSPEPWTPGHGACSTSSAAIMATATSRNCDKLK-----SFH 395
+P P + P A P P+P +P + + ++ +
Sbjct: 10636 KVPEVPKVAVPEKKVPEAIP-PKPESPPPEVFEEPEEVALEEPPAEVVEEPEPAAPPQVT 10694
Query: 396 LSPRGP-PTSEPPPVPANKPKFLKIAEEDPPREAAMPGLFVPPVAPR----PPALKLPVP 450
+ P+ P P + P V A KP+ + + P+E +P VP V P+ PPA VP
Sbjct: 10695 VPPKKPVPEKKAPAVVAKKPELPPVKVPEVPKEV-VPEKKVPLVVPKKPEAPPAKVPEVP 10753
Query: 451 EAMARPAVLPRPEKPQLP 468
+ + + P+KP++P
Sbjct: 10754 KEVVPEKKVAVPKKPEVP 10771
Score = 52.4 bits (124), Expect = 1e-06
Identities = 61/254 (24%), Positives = 90/254 (35%), Gaps = 43/254 (16%)
Query: 235 DEDDSYLEPDSPEPGRLEDALMHPPAYPPPPVPTPRKPAFS--DMPRAHSFTSKGPGPLL 292
+E + + +P +P G + PP PP V ++P ++P+ K P
Sbjct: 10428 EEVEVFEKPKAPPKGPEISEKIIPPKKPPTKVVPRKEPPAKVPEVPKKIVVEEKVRVPEE 10487
Query: 293 PPPPPKHGLPDVGLAAEDSKRDPLCPRRAEPCPRVPATPRRMSDPPLSTMPTAPGLRKPP 352
P PP +P+V L P+ P +VP P + + P +P AP P
Sbjct: 10488 PRVPPTK-VPEV-----------LPPKEVVPEKKVPVPPAKKPEAPPPKVPEAPKEVVP- 10534
Query: 353 CFRESASPSPEPWTPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSEP------ 406
E P P P P A + + + P PP P
Sbjct: 10535 ---EKKVPVPPPKKPEVPPTKVPEVPKAAVPEKKVPEAIPP---KPESPPPEVPEAPKEV 10588
Query: 407 ------PPVPANKPKFLKIAEEDPPREAAMPGLFVP---PVAPRPPALKLP------VPE 451
P P KP+ + + P+E +P VP P P P K+P VPE
Sbjct: 10589 VPEKKVPAAPPKKPEVTPVKVPEAPKEV-VPEKKVPVPPPKKPEVPPTKVPEVPKVAVPE 10647
Query: 452 AMARPAVLPRPEKP 465
A+ P+PE P
Sbjct: 10648 KKVPEAIPPKPESP 10661
Score = 48.9 bits (115), Expect = 1e-05
Identities = 66/285 (23%), Positives = 102/285 (35%), Gaps = 46/285 (16%)
Query: 214 ERPVDISLSPYPTDNEDYEHDDEDDSYLEPDSPEPGRLEDALMHPPAYPPPPVPTPRKPA 273
E+ V ++ P P ++ ++ LE E + P PP P P K
Sbjct: 10647 EKKVPEAIPPKPESPPPEVFEEPEEVALEEPPAEVVEEPEPAAPPQVTVPPKKPVPEK-- 10704
Query: 274 FSDMPRAHSFTSKGP--GPLLPPPPPKHGLPDVGLAAEDSKRDPLCPRRAEPCPR--VP- 328
+A + +K P P+ P PK +P+ + K+ P + P+ VP
Sbjct: 10705 -----KAPAVVAKKPELPPVKVPEVPKEVVPEKKVPLVVPKKPEAPPAKVPEVPKEVVPE 10759
Query: 329 ---ATPRRMSDPP--LSTMPTAPGLRKPPCF---RESASPSPEPWTPGHGACSTSSAAIM 380
A P++ PP + +P P L + P + SP PE + A
Sbjct: 10760 KKVAVPKKPEVPPAKVPEVPKKPVLEEKPAVPVPERAESPPPEVYEEPEEIAPEEEIA-- 10817
Query: 381 ATATSRNCDKLKSFHLSPRGPPTSEPPPVPANKPKF--------LKIAEEDPPRE----- 427
++ K ++ P PP VP K +K E PP+E
Sbjct: 10818 -------PEEEKPVPVAEEEEPEVPPPAVPEEPKKIIPEKKVPVIKKPEAPPPKEPEPEK 10870
Query: 428 -AAMPGLFVPPVAPRPPALKLPVPEAMARPAVLPR---PEKPQLP 468
P L P P P K V E + + +P+ PEKPQ+P
Sbjct: 10871 VIEKPKLKPRPPPPPPAPPKEDVKEKIFQLKAIPKKKVPEKPQVP 10915
Score = 45.8 bits (107), Expect = 1e-04
Identities = 82/338 (24%), Positives = 115/338 (34%), Gaps = 65/338 (19%)
Query: 229 EDYEHDDEDDSYLEPDSPEPGRLEDA---LMHP----PAYPPPPVPTPRKPAFSDMPRAH 281
E+YE +E D Y E + E R E+ + P P P P P P KP P A
Sbjct: 9757 EEYEPTEEYDQYEEYEEREYERYEEHEEYITEPEKPIPVKPVPEEPVPTKPK---APPAK 9813
Query: 282 SFTSKGPGPLLPPPPPKHGLPDVGLAAEDSK-------RDPLCPRR----AEPCPRVPAT 330
P +P P PK P E+ K R + R EP +VP
Sbjct: 9814 VLKKAVPEEKVPVPIPKKLKPPPPKVPEEPKKVFEEKIRISITKREKEQVTEPAAKVPMK 9873
Query: 331 PRRM---SDPPLSTMPTAPGLRKPPCFRESASPSPEPWTPGHGACSTSSAAIMATATSRN 387
P+R+ P+ AP +R P +E PE T +
Sbjct: 9874 PKRVVAEEKVPVPRKEVAPPVRVPEVPKEL---EPEE-VAFEEEVVTHVEEYLVEEEEEY 9929
Query: 388 CDKLKSFHLS--------------PRGPPTSEPPPVPANK---------PKFLKIAEEDP 424
+ + F PR P E PVP K P+ K EE
Sbjct: 9930 IHEEEEFITEEEVVPVIPVKVPEVPRKPVPEEKKPVPVPKKKEAPPAKVPEVPKKPEEKV 9989
Query: 425 ----PREAAMPGLFVPPVAPRP-PALKLPVP---EAMARPAVLPRPEKPQLPHLQRSPPD 476
P++ P VP V +P P K+PVP + A PA +P K +P + P
Sbjct: 9990 PVLIPKKEKPPPAKVPEVPKKPVPEEKVPVPVPKKVEAPPAKVPEVPKKPVPEKKVPVPA 10049
Query: 477 GQSFRSFSFEKPRQPSQADTGGDDSDEDYEKVPLPNSV 514
+ + + P P + E+ + P+P V
Sbjct: 10050 PKKVEAPPAKVPEVPKKL------IPEEKKPTPVPKKV 10081
Score = 44.3 bits (103), Expect = 3e-04
Identities = 63/263 (23%), Positives = 90/263 (34%), Gaps = 30/263 (11%)
Query: 242 EPDSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPPKHG- 300
+P+SP P E P P P P+KP + + + P +P PPPK
Sbjct: 10573 KPESPPPEVPEAPKEVVPEKKVPAAP-PKKPEVTPVKVPEAPKEVVPEKKVPVPPPKKPE 10631
Query: 301 -----LPDVGLAAEDSKRDP--LCPRRAEPCPRVPATPRRMS--DPPLSTMPTAPGLRKP 351
+P+V A K+ P + P+ P P V P ++ +PP + P
Sbjct: 10632 VPPTKVPEVPKVAVPEKKVPEAIPPKPESPPPEVFEEPEEVALEEPPAEVVEEPEPAAPP 10691
Query: 352 PCFRESASPSPEPWTPGHGACSTSSAAIMATATSRNCDKLKSFHL----SPRGPPTSEPP 407
P PE P A + + K L P PP P
Sbjct: 10692 QVTVPPKKPVPEKKAPAVVAKKPELPPVKVPEVPKEVVPEKKVPLVVPKKPEAPPAKVPE 10751
Query: 408 P----VPANKPKFLKIAEEDP------PREAAM---PGLFVPPVAPRPPALKLPVPEAMA 454
VP K K E P P++ + P + VP A PP PE +A
Sbjct: 10752 VPKEVVPEKKVAVPKKPEVPPAKVPEVPKKPVLEEKPAVPVPERAESPPPEVYEEPEEIA 10811
Query: 455 -RPAVLPRPEKPQLPHLQRSPPD 476
+ P EKP +P + P+
Sbjct: 10812 PEEEIAPEEEKP-VPVAEEEEPE 10833
Score = 42.7 bits (99), Expect = 0.001
Identities = 52/208 (25%), Positives = 74/208 (35%), Gaps = 23/208 (11%)
Query: 243 PDSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPPKHGLP 302
P PEP ++ + P PPPP P P K + K P P P K L
Sbjct: 10863 PKEPEPEKVIEKPKLKPR-PPPPPPAPPKEDVKEKIFQLKAIPKKKVPEKPQVPEKVELT 10921
Query: 303 DVGLAAEDSKRDPLCPRRAEPCPRVPATPRRMSDPPLSTMPTAPGLRKPPCFRESASPSP 362
+ + + K L P R +P P+ + + LRK P E P
Sbjct: 10922 PLKVPGGEKKVRKLLPER-KPEPKEEVVLKSV-------------LRKRP---EEEEPKV 10964
Query: 363 EPWTPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSEPPPVPANKPKF-LKIAE 421
EP A+ + ++++ ++ R EP VP KP L E
Sbjct: 10965 EP----KKLEKVKKPAVPEPPPPKPVEEVEVPTVTKRERKIPEPTKVPEIKPAIPLPAPE 11020
Query: 422 EDPPREAAMPGLFVPPVAPRPPALKLPV 449
P EA + + PPV P P + PV
Sbjct: 11021 PKPKPEAEVKTIKPPPVEPEPTPIAAPV 11048
Score = 41.2 bits (95), Expect = 0.003
Identities = 53/241 (21%), Positives = 78/241 (32%), Gaps = 54/241 (22%)
Query: 242 EPDSPEPGRLEDA----------LMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPL 291
EP+ P P E+ ++ P PPP P P K + P+ P
Sbjct: 10831 EPEVPPPAVPEEPKKIIPEKKVPVIKKPEAPPPKEPEPEKVI--EKPKLK--------PR 10880
Query: 292 LPPPPPKHGLPDVGLAAEDSKRDPLCPRRAEPCPRVPATPRRMSDPPLSTMPTAPGLRKP 351
PPPPP DV ++ + +A P +VP P+ L+ + G +K
Sbjct: 10881 PPPPPPAPPKEDV--------KEKIFQLKAIPKKKVPEKPQVPEKVELTPLKVPGGEKKV 10932
Query: 352 PCFRESASPSPEPWTPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSEPPPVPA 411
P P+ + + R P EP P
Sbjct: 10933 RKLLPERKPEPK-----------EEVVLKSVLRKR--------------PEEEEPKVEPK 10967
Query: 412 NKPKFLKIAEEDPPREAAMPGLFVPPVAPRPPALKLPVPEAMARPAV-LPRPEKPQLPHL 470
K K A +PP + + VP V R + P +PA+ LP PE P
Sbjct: 10968 KLEKVKKPAVPEPPPPKPVEEVEVPTVTKRERKIPEPTKVPEIKPAIPLPAPEPKPKPEA 11027
Query: 471 Q 471
+
Sbjct: 11028 E 11028
Score = 37.4 bits (85), Expect = 0.041
Identities = 59/276 (21%), Positives = 98/276 (35%), Gaps = 55/276 (19%)
Query: 227 DNEDYEHDDEDDSYLEPDSPE-PGRLEDALMHPPAYPPPPVPTPRK----PA-FSDMPRA 280
+ E+Y H++E+ E P P ++ + P PVP P+K PA ++P+
Sbjct: 9925 EEEEYIHEEEEFITEEEVVPVIPVKVPEVPRKPVPEEKKPVPVPKKKEAPPAKVPEVPKK 9984
Query: 281 HSFT-------SKGPGPLLPPPPPKHGLPDVGLAAEDSK-------RDPLCPRRAEPCPR 326
+ P P P PK +P+ + K + P P++ P +
Sbjct: 9985 PEEKVPVLIPKKEKPPPAKVPEVPKKPVPEEKVPVPVPKKVEAPPAKVPEVPKKPVPEKK 10044
Query: 327 VPATPRRMSDPPLSTMPTAPGLRKPPCFRESASPSPEPWTPGHGACSTSSAAIMATATSR 386
VP + + P + +P P P E P+P P
Sbjct: 10045 VPVPAPKKVEAPPAKVPEVPKKLIP----EEKKPTPVP---------------------- 10078
Query: 387 NCDKLKSFHLSPRGPPTSEPPPVPANKPKFLKI--AEEDPPREAAMPGLFVPPVAPRPPA 444
K P+ P EP PVP P+ ++ EE P E +P V P
Sbjct: 10079 ----KKVEAPPPKVPKKREPVPVPVALPQEEEVLFEEEIVPEEEVLPE--EEEVLPEEEE 10132
Query: 445 LKLPVPEAMARPAVLPRPEKPQLPHLQRSPPDGQSF 480
+ E + +P PE+ ++P + P+ + F
Sbjct: 10133 VLPEEEEVLPEEEEIP-PEEEEVPPEEEYVPEEEEF 10167
Score = 33.9 bits (76), Expect = 0.46
Identities = 44/220 (20%), Positives = 73/220 (33%), Gaps = 31/220 (14%)
Query: 214 ERPVDISLSPYPTDNEDYEHDDEDDSYLEPDSPEPGRLEDAL--MHPPAYPPPPVPTPRK 271
E +S+S Y + + E + E Y + PE +E+ L + P T R+
Sbjct: 9499 EEEEGVSISVYREEEREEEEEAEVTEYEVMEEPEEYVVEEKLHIISKRVEAEPAEVTERQ 9558
Query: 272 PAFSDMPRAHSFTSKGPGPLLPPPPPKHGLPDVGLAAEDSKRDPLCPRRAEPCPRVPATP 331
+ + P P P PK +P+ + A K++ + P P+VP P
Sbjct: 9559 EKKIVLKPKIPAKIEEPPPAKVPEAPKKIVPEKKVPAPVPKKEKVPP------PKVPEEP 9612
Query: 332 RRMSDPPLSTMPTAPGLRKPPCFRESASPSPEPWTPGHGACSTSSAAIMATATSRNCDKL 391
++ P + PP + P P T H + ++A
Sbjct: 9613 KK----------PVPEKKVPPKVIKMEEPLPAKVTERHMQITQEEKVLVAVT-------- 9654
Query: 392 KSFHLSPRGPPTSEPPPVPANKPKFLKIAEEDPPREAAMP 431
PP + P P K+ + P RE P
Sbjct: 9655 -----KKEAPPKARVPEEPKRAVPEEKVLKLKPKREEEPP 9689
Score = 32.3 bits (72), Expect = 1.3
Identities = 26/85 (30%), Positives = 32/85 (37%), Gaps = 7/85 (8%)
Query: 392 KSFHLSPRGPPT-SEPPPVPANKPKFLKIAEEDPPREAAMPGLFVPPVAPRPPALKLPVP 450
K L P+ P EPPP + + E+ P PP P P K PVP
Sbjct: 9560 KKIVLKPKIPAKIEEPPPAKVPEAPKKIVPEKKVPAPVPKKEKVPPPKVPEEP--KKPVP 9617
Query: 451 EAMARPAVL----PRPEKPQLPHLQ 471
E P V+ P P K H+Q
Sbjct: 9618 EKKVPPKVIKMEEPLPAKVTERHMQ 9642
Score = 30.0 bits (66), Expect = 6.6
Identities = 42/211 (19%), Positives = 77/211 (36%), Gaps = 30/211 (14%)
Query: 166 FFSASSEEERKSWMALLRREIGHFHEKKDLPLDTSDSSSDTDSFYGAVERPVDISLSPYP 225
FF++ +EEE + +++EI ++ + + S E+P ++P P
Sbjct: 9248 FFASHTEEEVSVTVPEVQKEIV---TEEKIHVAISKRVEPPPKVPELPEKPAPEEVAPVP 9304
Query: 226 TDNEDYEHDDEDDSYLEPDSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSD-MPRAHSFT 284
+ + + PE + PA PP P+KP + +P +
Sbjct: 9305 IPKKVEPPAPKVPEVPKKPVPEEKKPVPVPKKEPAAPPKVPEVPKKPVPEEKIPVPVAKK 9364
Query: 285 SKGPGPLLPP--------------------PPPKHGLPDVGLAAEDSKRDPLCPRRAE-- 322
+ P +P PPP +P++ +R P+ PR+ E
Sbjct: 9365 KEAPPAKVPEVQKGVVTEEKITIVTQREESPPP--AVPEIPKKKVPEERKPV-PRKEEEV 9421
Query: 323 -PCPRVPATPRRMSDPPLSTMPTAPGLRKPP 352
P P+VPA P++ +P + PP
Sbjct: 9422 PPPPKVPALPKKPVPEEKVAVPVPVAKKAPP 9452
>gi|122937496 WAS/WASL interacting protein family, member 3 [Homo
sapiens]
Length = 483
Score = 57.8 bits (138), Expect = 3e-08
Identities = 56/208 (26%), Positives = 75/208 (36%), Gaps = 56/208 (26%)
Query: 258 PPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLL-------------------PPPPP- 297
PP PPPP P P P S P S PGPL PPPPP
Sbjct: 176 PPTPPPPPPPLP-PPLPSSSPIKTPLVSP-PGPLTKGNLPVVAPPVPCAPPPPPPPPPPT 233
Query: 298 KHGLPDVGLAAEDSKRDPLCPRRAEPCPRVPATPRRMSDPPLSTMPTA--PGLRKPPCFR 355
LP + ++ + + L P P P PPL +P PGL+ P
Sbjct: 234 PPPLPPASVLSDKAVKPQLAPLHLPPIP-----------PPLPLLPPCGYPGLKAEPASP 282
Query: 356 ESAS---PSPEPWTPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSEPPPVPAN 412
+ P+P P P + +CS ++ L + L + PPP+P
Sbjct: 283 AQDAQEPPAPPPPLPPYASCSPRAS-------------LPAPPLPGVNSSSETPPPLPPK 329
Query: 413 KPKFLKIAEEDPPREAAMPGLFVPPVAP 440
P F + PP++A L PP P
Sbjct: 330 SPSF-----QAPPQKAGAQALPAPPAPP 352
Score = 37.7 bits (86), Expect = 0.032
Identities = 42/134 (31%), Positives = 49/134 (36%), Gaps = 19/134 (14%)
Query: 242 EPDSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPG--------PLLP 293
EP SP +DA PPA PPPP+P P S PRA PG P LP
Sbjct: 278 EPASPA----QDA-QEPPA-PPPPLP----PYASCSPRASLPAPPLPGVNSSSETPPPLP 327
Query: 294 PPPPKHGLPDVGLAAEDSKRDPLCPRRAEPCPRVPATPRRMSDPPLSTMPTAPGLRKPPC 353
P P P A+ P P ++P + R + P AP R P
Sbjct: 328 PKSPSFQAPPQKAGAQALPAPP-APPGSQPFLQKKRHGRPGAGGGKLNPPPAPPARSPTT 386
Query: 354 FRESASPSPEPWTP 367
S S WTP
Sbjct: 387 ELSSKSQQATAWTP 400
Score = 37.0 bits (84), Expect = 0.054
Identities = 60/238 (25%), Positives = 77/238 (32%), Gaps = 62/238 (26%)
Query: 256 MHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPPKHGLPDVGLAAEDSKRDP 315
M P PPPP+P P P PL PPPP P V D
Sbjct: 1 MPVPPPPPPPLPPP------------------PPPLGAPPPPPPSAPPV-------STDT 35
Query: 316 LCPRRAEPCPRVPATPRRMSDPPLSTMPTAPGLRKPPCFRESASPSPEPW----TPGHGA 371
RRA+P R L+ + LRK + ++P E G G+
Sbjct: 36 SSLRRADPKGR---------SALLADIQQGTRLRKVTQINDRSAPQIESSKGTNKEGGGS 86
Query: 372 CSTSSAA--------------IMATATSRNCDKLK------SFHLSPRGP-PTSEPPPVP 410
+T A+ ++ A R+ K S SPR P T P +P
Sbjct: 87 ANTRGASTPPTLGDLFAGGFPVLRPAGQRDVAGGKTGQGPGSRAPSPRLPNKTISGPLIP 146
Query: 411 ANKPKFLKIAEEDPPREAAMPGLFV---PPVAPRPPALKLPVPEAMARPAVLPRPEKP 465
P+ +E A P V PP P PP LP P + P P P
Sbjct: 147 PASPRLGNTSEAHGAARTAPPRPNVPAPPPPTPPPPPPPLPPPLPSSSPIKTPLVSPP 204
Score = 37.0 bits (84), Expect = 0.054
Identities = 27/85 (31%), Positives = 36/85 (42%), Gaps = 6/85 (7%)
Query: 397 SPRGPPTSEPPPVPANKPKFLKIAEEDPPREAAMPGLFVPPV---APRPPALKLPVPEAM 453
+P PP PPP+P++ P + P + PPV P PP P P +
Sbjct: 178 TPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPPPPTPPPL 237
Query: 454 ARPAVL-PRPEKPQLP--HLQRSPP 475
+VL + KPQL HL PP
Sbjct: 238 PPASVLSDKAVKPQLAPLHLPPIPP 262
>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
Length = 1012
Score = 57.8 bits (138), Expect = 3e-08
Identities = 91/392 (23%), Positives = 142/392 (36%), Gaps = 40/392 (10%)
Query: 119 KSSTSASPQGAFSLSGYNR---VMRAAEETTSNNVFPFKIIHISKKHRTWFFSASSEEER 175
+SS SP A + S ++ V ++A++ P K +K+ R S + E +R
Sbjct: 53 RSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKS---NKRQREKVASDTEEADR 109
Query: 176 KSWMALLRREIGHFHEKKDLPLDTSDSSSDTDSFYGAVERPVDI-----SLSPYPTDNED 230
S +EI + + ++SDS S D P DI S SP +D
Sbjct: 110 TSSKKTKTQEISRPNSPSEGEGESSDSRSVNDE---GSSDPKDIDQDNRSTSPSIPSPQD 166
Query: 231 YEHDDEDDSYLEPDSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGP 290
E D + + + +P L+ PA P TP+ P P A + +G P
Sbjct: 167 NESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQG-SP 225
Query: 291 LLPPPPPKHGLPDVGLAAEDSKRDPLCPRRAEPCPRVPATPRRMSDPPLSTMPTAPGLRK 350
P + P + ++ P + P P P P PPL + + G
Sbjct: 226 TASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPP--PHPSPHPPLQPLTGSAG--- 280
Query: 351 PPCFRESASPSPEPWTPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSEP---P 407
+ SA +P P HG ++ A ++ + F L P+ P
Sbjct: 281 ----QPSAPSHAQP--PLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTS 334
Query: 408 PVPANKPKFLKIA-------EEDPPREAAMPG--LFVPPVAPRP--PALKLPVPEAMARP 456
P A L++ + PPRE +P L +P + P P P +LP P+A P
Sbjct: 335 PAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHP 394
Query: 457 AVLPRPEKPQLPHLQRSPPDGQSFRSFSFEKP 488
L P + PP + S S P
Sbjct: 395 PHLSGPSPFSMNANLPPPPALKPLSSLSTHHP 426
Score = 51.2 bits (121), Expect = 3e-06
Identities = 63/269 (23%), Positives = 86/269 (31%), Gaps = 61/269 (22%)
Query: 258 PPAYPPPPVPTPRKPA-------------FSDMPRAHSFTSKGP-----GPLL--PPPPP 297
PP+ PPP P+P P P H GP GPLL P PP
Sbjct: 257 PPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQ 316
Query: 298 KHGLP---------------------DVGLAAEDSKRDPLCPRRAEPCPRVPATPRRMSD 336
GLP + L A S P R +P P P +
Sbjct: 317 PFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKP 376
Query: 337 PPLSTMPTAPGLRKPPCFRESASPSPEPWTPGHGACSTSSAAIMATATSRNCDKLKSFHL 396
PP + +P P + + PSP + +A + + L + H
Sbjct: 377 PPTTPIPQLPAPQAHKHPPHLSGPSP----------FSMNANLPPPPALKPLSSLSTHHP 426
Query: 397 SPRGPPT------SEPPPVPANKPKFLKIAEEDPPREAAMPGLFVPPVAPRPPALKLPV- 449
PP S+P P +P L ++ PP A+ P + VAP+PP + P
Sbjct: 427 PSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFV 486
Query: 450 ---PEAMARPAVLPRPEKPQLPHLQRSPP 475
P + P P P PP
Sbjct: 487 PGGPPPITPPTCPSTSTPPAGPGTSAQPP 515
Score = 43.9 bits (102), Expect = 4e-04
Identities = 46/190 (24%), Positives = 62/190 (32%), Gaps = 11/190 (5%)
Query: 246 PEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPPKHGL-PDV 304
P P + L PPA P + P + P P P P PP GL
Sbjct: 400 PSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPP--GLTQSQ 457
Query: 305 GLAAEDSKRDPLCPRRAEPCPRVPATPRRMSDPPLSTMPTAPGLRKPPCFRESASPSPEP 364
L + P + P P P PP T PT P PP A P
Sbjct: 458 NLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPP-----AGPGTSA 512
Query: 365 WTPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSEPPPVPANKPKFLKIAEEDP 424
P GA ++ + ++ ++K L P S PPP + P+ + D
Sbjct: 513 QPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVV---DT 569
Query: 425 PREAAMPGLF 434
P A+ F
Sbjct: 570 PSHASQSARF 579
Score = 31.6 bits (70), Expect = 2.3
Identities = 29/112 (25%), Positives = 39/112 (34%), Gaps = 22/112 (19%)
Query: 401 PPTSEPPPVPANKPKFLKIAEEDPPREAAMPGLFVPPVAPRPPALKLPVPEAMARPAVLP 460
PP + P P P + + P + P +P A PVP + A
Sbjct: 201 PPGTPQLPTPGPTPSATAVPPQGSPTASQAPN--------QPQAPTAPVPHTHIQQAPAL 252
Query: 461 RPEKPQLPHLQRSPPDGQSFRSFSFEKPRQPSQADTG--GDDSDEDYEKVPL 510
P++P PH PP S P P Q TG G S + + PL
Sbjct: 253 HPQRPPSPH----PPPHPS--------PHPPLQPLTGSAGQPSAPSHAQPPL 292
>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 57.8 bits (138), Expect = 3e-08
Identities = 91/392 (23%), Positives = 142/392 (36%), Gaps = 40/392 (10%)
Query: 119 KSSTSASPQGAFSLSGYNR---VMRAAEETTSNNVFPFKIIHISKKHRTWFFSASSEEER 175
+SS SP A + S ++ V ++A++ P K +K+ R S + E +R
Sbjct: 607 RSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKS---NKRQREKVASDTEEADR 663
Query: 176 KSWMALLRREIGHFHEKKDLPLDTSDSSSDTDSFYGAVERPVDI-----SLSPYPTDNED 230
S +EI + + ++SDS S D P DI S SP +D
Sbjct: 664 TSSKKTKTQEISRPNSPSEGEGESSDSRSVNDE---GSSDPKDIDQDNRSTSPSIPSPQD 720
Query: 231 YEHDDEDDSYLEPDSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGP 290
E D + + + +P L+ PA P TP+ P P A + +G P
Sbjct: 721 NESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQG-SP 779
Query: 291 LLPPPPPKHGLPDVGLAAEDSKRDPLCPRRAEPCPRVPATPRRMSDPPLSTMPTAPGLRK 350
P + P + ++ P + P P P P PPL + + G
Sbjct: 780 TASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPP--PHPSPHPPLQPLTGSAG--- 834
Query: 351 PPCFRESASPSPEPWTPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSEP---P 407
+ SA +P P HG ++ A ++ + F L P+ P
Sbjct: 835 ----QPSAPSHAQP--PLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTS 888
Query: 408 PVPANKPKFLKIA-------EEDPPREAAMPG--LFVPPVAPRP--PALKLPVPEAMARP 456
P A L++ + PPRE +P L +P + P P P +LP P+A P
Sbjct: 889 PAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHP 948
Query: 457 AVLPRPEKPQLPHLQRSPPDGQSFRSFSFEKP 488
L P + PP + S S P
Sbjct: 949 PHLSGPSPFSMNANLPPPPALKPLSSLSTHHP 980
Score = 51.2 bits (121), Expect = 3e-06
Identities = 63/269 (23%), Positives = 86/269 (31%), Gaps = 61/269 (22%)
Query: 258 PPAYPPPPVPTPRKPA-------------FSDMPRAHSFTSKGP-----GPLL--PPPPP 297
PP+ PPP P+P P P H GP GPLL P PP
Sbjct: 811 PPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQ 870
Query: 298 KHGLP---------------------DVGLAAEDSKRDPLCPRRAEPCPRVPATPRRMSD 336
GLP + L A S P R +P P P +
Sbjct: 871 PFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKP 930
Query: 337 PPLSTMPTAPGLRKPPCFRESASPSPEPWTPGHGACSTSSAAIMATATSRNCDKLKSFHL 396
PP + +P P + + PSP + +A + + L + H
Sbjct: 931 PPTTPIPQLPAPQAHKHPPHLSGPSP----------FSMNANLPPPPALKPLSSLSTHHP 980
Query: 397 SPRGPPT------SEPPPVPANKPKFLKIAEEDPPREAAMPGLFVPPVAPRPPALKLPV- 449
PP S+P P +P L ++ PP A+ P + VAP+PP + P
Sbjct: 981 PSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFV 1040
Query: 450 ---PEAMARPAVLPRPEKPQLPHLQRSPP 475
P + P P P PP
Sbjct: 1041 PGGPPPITPPTCPSTSTPPAGPGTSAQPP 1069
Score = 43.9 bits (102), Expect = 4e-04
Identities = 46/190 (24%), Positives = 62/190 (32%), Gaps = 11/190 (5%)
Query: 246 PEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPPKHGL-PDV 304
P P + L PPA P + P + P P P P PP GL
Sbjct: 954 PSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPP--GLTQSQ 1011
Query: 305 GLAAEDSKRDPLCPRRAEPCPRVPATPRRMSDPPLSTMPTAPGLRKPPCFRESASPSPEP 364
L + P + P P P PP T PT P PP A P
Sbjct: 1012 NLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPP-----AGPGTSA 1066
Query: 365 WTPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSEPPPVPANKPKFLKIAEEDP 424
P GA ++ + ++ ++K L P S PPP + P+ + D
Sbjct: 1067 QPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVV---DT 1123
Query: 425 PREAAMPGLF 434
P A+ F
Sbjct: 1124 PSHASQSARF 1133
Score = 31.6 bits (70), Expect = 2.3
Identities = 29/112 (25%), Positives = 39/112 (34%), Gaps = 22/112 (19%)
Query: 401 PPTSEPPPVPANKPKFLKIAEEDPPREAAMPGLFVPPVAPRPPALKLPVPEAMARPAVLP 460
PP + P P P + + P + P +P A PVP + A
Sbjct: 755 PPGTPQLPTPGPTPSATAVPPQGSPTASQAPN--------QPQAPTAPVPHTHIQQAPAL 806
Query: 461 RPEKPQLPHLQRSPPDGQSFRSFSFEKPRQPSQADTG--GDDSDEDYEKVPL 510
P++P PH PP S P P Q TG G S + + PL
Sbjct: 807 HPQRPPSPH----PPPHPS--------PHPPLQPLTGSAGQPSAPSHAQPPL 846
>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 57.8 bits (138), Expect = 3e-08
Identities = 91/392 (23%), Positives = 142/392 (36%), Gaps = 40/392 (10%)
Query: 119 KSSTSASPQGAFSLSGYNR---VMRAAEETTSNNVFPFKIIHISKKHRTWFFSASSEEER 175
+SS SP A + S ++ V ++A++ P K +K+ R S + E +R
Sbjct: 607 RSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKS---NKRQREKVASDTEEADR 663
Query: 176 KSWMALLRREIGHFHEKKDLPLDTSDSSSDTDSFYGAVERPVDI-----SLSPYPTDNED 230
S +EI + + ++SDS S D P DI S SP +D
Sbjct: 664 TSSKKTKTQEISRPNSPSEGEGESSDSRSVNDE---GSSDPKDIDQDNRSTSPSIPSPQD 720
Query: 231 YEHDDEDDSYLEPDSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGP 290
E D + + + +P L+ PA P TP+ P P A + +G P
Sbjct: 721 NESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQG-SP 779
Query: 291 LLPPPPPKHGLPDVGLAAEDSKRDPLCPRRAEPCPRVPATPRRMSDPPLSTMPTAPGLRK 350
P + P + ++ P + P P P P PPL + + G
Sbjct: 780 TASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPP--PHPSPHPPLQPLTGSAG--- 834
Query: 351 PPCFRESASPSPEPWTPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSEP---P 407
+ SA +P P HG ++ A ++ + F L P+ P
Sbjct: 835 ----QPSAPSHAQP--PLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTS 888
Query: 408 PVPANKPKFLKIA-------EEDPPREAAMPG--LFVPPVAPRP--PALKLPVPEAMARP 456
P A L++ + PPRE +P L +P + P P P +LP P+A P
Sbjct: 889 PAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHP 948
Query: 457 AVLPRPEKPQLPHLQRSPPDGQSFRSFSFEKP 488
L P + PP + S S P
Sbjct: 949 PHLSGPSPFSMNANLPPPPALKPLSSLSTHHP 980
Score = 51.2 bits (121), Expect = 3e-06
Identities = 63/269 (23%), Positives = 86/269 (31%), Gaps = 61/269 (22%)
Query: 258 PPAYPPPPVPTPRKPA-------------FSDMPRAHSFTSKGP-----GPLL--PPPPP 297
PP+ PPP P+P P P H GP GPLL P PP
Sbjct: 811 PPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQ 870
Query: 298 KHGLP---------------------DVGLAAEDSKRDPLCPRRAEPCPRVPATPRRMSD 336
GLP + L A S P R +P P P +
Sbjct: 871 PFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKP 930
Query: 337 PPLSTMPTAPGLRKPPCFRESASPSPEPWTPGHGACSTSSAAIMATATSRNCDKLKSFHL 396
PP + +P P + + PSP + +A + + L + H
Sbjct: 931 PPTTPIPQLPAPQAHKHPPHLSGPSP----------FSMNANLPPPPALKPLSSLSTHHP 980
Query: 397 SPRGPPT------SEPPPVPANKPKFLKIAEEDPPREAAMPGLFVPPVAPRPPALKLPV- 449
PP S+P P +P L ++ PP A+ P + VAP+PP + P
Sbjct: 981 PSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFV 1040
Query: 450 ---PEAMARPAVLPRPEKPQLPHLQRSPP 475
P + P P P PP
Sbjct: 1041 PGGPPPITPPTCPSTSTPPAGPGTSAQPP 1069
Score = 43.9 bits (102), Expect = 4e-04
Identities = 46/190 (24%), Positives = 62/190 (32%), Gaps = 11/190 (5%)
Query: 246 PEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPPKHGL-PDV 304
P P + L PPA P + P + P P P P PP GL
Sbjct: 954 PSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPP--GLTQSQ 1011
Query: 305 GLAAEDSKRDPLCPRRAEPCPRVPATPRRMSDPPLSTMPTAPGLRKPPCFRESASPSPEP 364
L + P + P P P PP T PT P PP A P
Sbjct: 1012 NLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPP-----AGPGTSA 1066
Query: 365 WTPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSEPPPVPANKPKFLKIAEEDP 424
P GA ++ + ++ ++K L P S PPP + P+ + D
Sbjct: 1067 QPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVV---DT 1123
Query: 425 PREAAMPGLF 434
P A+ F
Sbjct: 1124 PSHASQSARF 1133
Score = 31.6 bits (70), Expect = 2.3
Identities = 29/112 (25%), Positives = 39/112 (34%), Gaps = 22/112 (19%)
Query: 401 PPTSEPPPVPANKPKFLKIAEEDPPREAAMPGLFVPPVAPRPPALKLPVPEAMARPAVLP 460
PP + P P P + + P + P +P A PVP + A
Sbjct: 755 PPGTPQLPTPGPTPSATAVPPQGSPTASQAPN--------QPQAPTAPVPHTHIQQAPAL 806
Query: 461 RPEKPQLPHLQRSPPDGQSFRSFSFEKPRQPSQADTG--GDDSDEDYEKVPL 510
P++P PH PP S P P Q TG G S + + PL
Sbjct: 807 HPQRPPSPH----PPPHPS--------PHPPLQPLTGSAGQPSAPSHAQPPL 846
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 57.4 bits (137), Expect = 4e-08
Identities = 68/314 (21%), Positives = 100/314 (31%), Gaps = 34/314 (10%)
Query: 214 ERPVDISLSPYPTDNEDYEHDDEDDSYLEPDSPEPGRLEDALMHPPAYPPPPVPTPRKPA 273
+ P ++ PT ++ + P P P ++ P P P PT K
Sbjct: 230 KEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPA---PTTPKEPAPTTTKEP 286
Query: 274 FSDMPRAHSFTSKGPGPLLPPPPPKHGLPDVGLAAEDSKRDPLCPRRAEPCPRVPATPRR 333
++ T K P P P P A + ++P EP P P P
Sbjct: 287 APTTTKSAPTTPKEPAPTTPKKP-----------APTTPKEPAPTTPKEPTPTTPKEPAP 335
Query: 334 MSDPPLST-----MPTAPGLRKPPCFRESA-----------SPSPEPWTPGHGACSTSSA 377
+ P T PTAP P +E A + P P TP A +T+ +
Sbjct: 336 TTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKS 395
Query: 378 AIMATATSRNCDKLKSFHLSPRGP-PTSEPPPVPANKPKFLKIAEEDPPREAAMPGLFVP 436
A T KS +P+ P PT+ P P + + P
Sbjct: 396 A-PTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTT 454
Query: 437 PVAPRPPALKLPVPEAMARPA-VLPRPEKPQLPHLQRSPPDGQSFRSFSFEKPRQPSQAD 495
P P P K P P PA P+ P P + +P + + EKP + +
Sbjct: 455 PKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPK-KLTPTTPEKLAPTTPEKPAPTTPEE 513
Query: 496 TGGDDSDEDYEKVP 509
+E P
Sbjct: 514 LAPTTPEEPTPTTP 527
Score = 52.8 bits (125), Expect = 9e-07
Identities = 67/267 (25%), Positives = 91/267 (34%), Gaps = 28/267 (10%)
Query: 223 PYPTDNEDYEHDD-EDDSYLEPDSPEPGRLEDALMHPPAYPPPPVP------TPRKPAFS 275
P PT E+ E+ + P+ P P + A + P P P P TP++PA +
Sbjct: 506 PAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPT 565
Query: 276 DMPRAHSFTSKGPGP--LLPPPPPKHGLPDVGLAAEDSKRDPLCPRRAEPCPRVP-ATPR 332
T KG P L P P P A + ++P +P P P T
Sbjct: 566 TPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAP 625
Query: 333 RMSDPPLSTMPTAPGLRKPPCFRESASPSPEPWTPGHGACSTSSAAIMATATSRNCDKLK 392
P T P P P + P P TP A + TS DK
Sbjct: 626 TTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDK-- 683
Query: 393 SFHLSPRGP----PTSEPPPVPANKPKFLKIAEEDPPREAAMPGLFVPPVAPRPPAL-KL 447
+P P PT+ P P K E PP + + P P + K
Sbjct: 684 ---PAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTS--EVSTPTTTKEPTTIHKS 738
Query: 448 P---VPEAMARP---AVLPRPEKPQLP 468
P PE A P A+ P++P +P
Sbjct: 739 PDESTPELSAEPTPKALENSPKEPGVP 765
Score = 48.5 bits (114), Expect = 2e-05
Identities = 72/311 (23%), Positives = 96/311 (30%), Gaps = 42/311 (13%)
Query: 242 EPDSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPPKHGL 301
EP P PA P P P P + T P L P P K
Sbjct: 449 EPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAP 508
Query: 302 PDVGLAAEDSKRDPLCPRRAEPCPRVP--ATPRRMSDP----PLSTMPTAPGLRKPPCFR 355
A + +P EP P P A P +P P PT P P +
Sbjct: 509 TTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPK 568
Query: 356 ESASPSPE-----------PWTPGHGACSTSSAAIMATATSRNCDK------LKSFHLSP 398
E+A +P+ P TP A + TS CDK + +P
Sbjct: 569 ETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTP 628
Query: 399 RGP-PTSEPPPVP----ANKPKFLKIAEEDPPREAAMPGLFVPPVA----------PRPP 443
+ P PT+ P P P LK P++ A P P P P
Sbjct: 629 KEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPA-PKELAPTTTKGPTSTTSDKPAPT 687
Query: 444 ALKLPVPEAMARPAVLPRPEKPQLPHLQRSPPDGQSFRSFSFEKPRQPSQADTGGDDSDE 503
K P PA P K P +PP S S + ++P+ D+S
Sbjct: 688 TPKETAPTTPKEPA--PTTPKKPAPTTPETPPPTTSEVS-TPTTTKEPTTIHKSPDESTP 744
Query: 504 DYEKVPLPNSV 514
+ P P ++
Sbjct: 745 ELSAEPTPKAL 755
Score = 44.3 bits (103), Expect = 3e-04
Identities = 51/202 (25%), Positives = 70/202 (34%), Gaps = 32/202 (15%)
Query: 291 LLPPPPPKHGLPDVGLAAEDSKRDPLCPRRAEPCPRVP-----ATPRRMSDPPLSTMPTA 345
+L P PK AE + + P EP P P TP+ + + + PT
Sbjct: 193 VLAKPTPK---------AETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTT 243
Query: 346 PGLRKP------PCFRESASPS----PEPWTPGHGACSTSSAAIMATATSRNCDKLKSFH 395
P P P + +P+ P P TP A +T+ T S +
Sbjct: 244 PKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAP 303
Query: 396 LSPRGP-PTS--EPPPVPANKPKFLKIAEEDPPREAAMPGLFVPPVAPRPPALKLPVPEA 452
+P+ P PT+ EP P +P E P + P P P P A K P P
Sbjct: 304 TTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAP---TTPKEPAPTAPKKPAPTT 360
Query: 453 MARPAVLPRPEKPQLPHLQRSP 474
PA P K P + P
Sbjct: 361 PKEPA--PTTPKEPAPTTTKEP 380
Score = 36.6 bits (83), Expect = 0.070
Identities = 56/242 (23%), Positives = 89/242 (36%), Gaps = 29/242 (11%)
Query: 244 DSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPP------P 297
D P P ++ P P P TP+KPA + TS+ P P P
Sbjct: 682 DKPAPTTPKETAPTTPKEPAPT--TPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSP 739
Query: 298 KHGLPDVGL-----AAEDSKRDPLCPRRAEPC---PRVPATPR-RMSDPPLSTMPTAPGL 348
P++ A E+S ++P P P P + T + + ++ L T P
Sbjct: 740 DESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETT-T 798
Query: 349 RKPPCFRESASPSPEPWTPGHGACSTSSAAIMAT--ATSRNCDKLKSFHLSPRGPPTSEP 406
P +E+A+ + E T +T+ T T LK+ L+P+ T +
Sbjct: 799 AAPKMTKETATTT-EKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKT 857
Query: 407 PPVPA--NKPKFLKIAEEDPPREAAMPGLFVPPVAPRPPALKLPVPEAMARPAVLPRPEK 464
NKP+ E P++ A P P+ P P + +P +PR K
Sbjct: 858 ITTTEIMNKPE-----ETAKPKDRATNSKATTP-KPQKPTKAPKKPTSTKKPKTMPRVRK 911
Query: 465 PQ 466
P+
Sbjct: 912 PK 913
Score = 34.3 bits (77), Expect = 0.35
Identities = 38/172 (22%), Positives = 54/172 (31%), Gaps = 25/172 (14%)
Query: 343 PTAPGLRKPPCFRESASPSPEPWTPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGP- 401
PT+ L KP E+ + P TP +T T +KS +P+ P
Sbjct: 189 PTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPA 248
Query: 402 -----------------PTSEPPPVPANKPKFLKIAEEDPPREAAMPGLFVPPVAPRPPA 444
T EP P +P E P + P P P P
Sbjct: 249 PTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAP---TTPKEPAPTT 305
Query: 445 LKLPVPEAMARPAVL----PRPEKPQLPHLQRSPPDGQSFRSFSFEKPRQPS 492
K P P PA P P P+ P P + + + P++P+
Sbjct: 306 PKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPA 357
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 57.4 bits (137), Expect = 4e-08
Identities = 68/314 (21%), Positives = 100/314 (31%), Gaps = 34/314 (10%)
Query: 214 ERPVDISLSPYPTDNEDYEHDDEDDSYLEPDSPEPGRLEDALMHPPAYPPPPVPTPRKPA 273
+ P ++ PT ++ + P P P ++ P P P PT K
Sbjct: 271 KEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPA---PTTPKEPAPTTTKEP 327
Query: 274 FSDMPRAHSFTSKGPGPLLPPPPPKHGLPDVGLAAEDSKRDPLCPRRAEPCPRVPATPRR 333
++ T K P P P P A + ++P EP P P P
Sbjct: 328 APTTTKSAPTTPKEPAPTTPKKP-----------APTTPKEPAPTTPKEPTPTTPKEPAP 376
Query: 334 MSDPPLST-----MPTAPGLRKPPCFRESA-----------SPSPEPWTPGHGACSTSSA 377
+ P T PTAP P +E A + P P TP A +T+ +
Sbjct: 377 TTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKS 436
Query: 378 AIMATATSRNCDKLKSFHLSPRGP-PTSEPPPVPANKPKFLKIAEEDPPREAAMPGLFVP 436
A T KS +P+ P PT+ P P + + P
Sbjct: 437 A-PTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTT 495
Query: 437 PVAPRPPALKLPVPEAMARPA-VLPRPEKPQLPHLQRSPPDGQSFRSFSFEKPRQPSQAD 495
P P P K P P PA P+ P P + +P + + EKP + +
Sbjct: 496 PKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPK-KLTPTTPEKLAPTTPEKPAPTTPEE 554
Query: 496 TGGDDSDEDYEKVP 509
+E P
Sbjct: 555 LAPTTPEEPTPTTP 568
Score = 52.8 bits (125), Expect = 9e-07
Identities = 67/267 (25%), Positives = 91/267 (34%), Gaps = 28/267 (10%)
Query: 223 PYPTDNEDYEHDD-EDDSYLEPDSPEPGRLEDALMHPPAYPPPPVP------TPRKPAFS 275
P PT E+ E+ + P+ P P + A + P P P P TP++PA +
Sbjct: 547 PAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPT 606
Query: 276 DMPRAHSFTSKGPGP--LLPPPPPKHGLPDVGLAAEDSKRDPLCPRRAEPCPRVP-ATPR 332
T KG P L P P P A + ++P +P P P T
Sbjct: 607 TPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAP 666
Query: 333 RMSDPPLSTMPTAPGLRKPPCFRESASPSPEPWTPGHGACSTSSAAIMATATSRNCDKLK 392
P T P P P + P P TP A + TS DK
Sbjct: 667 TTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDK-- 724
Query: 393 SFHLSPRGP----PTSEPPPVPANKPKFLKIAEEDPPREAAMPGLFVPPVAPRPPAL-KL 447
+P P PT+ P P K E PP + + P P + K
Sbjct: 725 ---PAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTS--EVSTPTTTKEPTTIHKS 779
Query: 448 P---VPEAMARP---AVLPRPEKPQLP 468
P PE A P A+ P++P +P
Sbjct: 780 PDESTPELSAEPTPKALENSPKEPGVP 806
Score = 48.5 bits (114), Expect = 2e-05
Identities = 72/311 (23%), Positives = 96/311 (30%), Gaps = 42/311 (13%)
Query: 242 EPDSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPPKHGL 301
EP P PA P P P P + T P L P P K
Sbjct: 490 EPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAP 549
Query: 302 PDVGLAAEDSKRDPLCPRRAEPCPRVP--ATPRRMSDP----PLSTMPTAPGLRKPPCFR 355
A + +P EP P P A P +P P PT P P +
Sbjct: 550 TTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPK 609
Query: 356 ESASPSPE-----------PWTPGHGACSTSSAAIMATATSRNCDK------LKSFHLSP 398
E+A +P+ P TP A + TS CDK + +P
Sbjct: 610 ETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTP 669
Query: 399 RGP-PTSEPPPVP----ANKPKFLKIAEEDPPREAAMPGLFVPPVA----------PRPP 443
+ P PT+ P P P LK P++ A P P P P
Sbjct: 670 KEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPA-PKELAPTTTKGPTSTTSDKPAPT 728
Query: 444 ALKLPVPEAMARPAVLPRPEKPQLPHLQRSPPDGQSFRSFSFEKPRQPSQADTGGDDSDE 503
K P PA P K P +PP S S + ++P+ D+S
Sbjct: 729 TPKETAPTTPKEPA--PTTPKKPAPTTPETPPPTTSEVS-TPTTTKEPTTIHKSPDESTP 785
Query: 504 DYEKVPLPNSV 514
+ P P ++
Sbjct: 786 ELSAEPTPKAL 796
Score = 44.3 bits (103), Expect = 3e-04
Identities = 51/202 (25%), Positives = 70/202 (34%), Gaps = 32/202 (15%)
Query: 291 LLPPPPPKHGLPDVGLAAEDSKRDPLCPRRAEPCPRVP-----ATPRRMSDPPLSTMPTA 345
+L P PK AE + + P EP P P TP+ + + + PT
Sbjct: 234 VLAKPTPK---------AETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTT 284
Query: 346 PGLRKP------PCFRESASPS----PEPWTPGHGACSTSSAAIMATATSRNCDKLKSFH 395
P P P + +P+ P P TP A +T+ T S +
Sbjct: 285 PKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAP 344
Query: 396 LSPRGP-PTS--EPPPVPANKPKFLKIAEEDPPREAAMPGLFVPPVAPRPPALKLPVPEA 452
+P+ P PT+ EP P +P E P + P P P P A K P P
Sbjct: 345 TTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAP---TTPKEPAPTAPKKPAPTT 401
Query: 453 MARPAVLPRPEKPQLPHLQRSP 474
PA P K P + P
Sbjct: 402 PKEPA--PTTPKEPAPTTTKEP 421
Score = 36.6 bits (83), Expect = 0.070
Identities = 56/242 (23%), Positives = 89/242 (36%), Gaps = 29/242 (11%)
Query: 244 DSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPP------P 297
D P P ++ P P P TP+KPA + TS+ P P P
Sbjct: 723 DKPAPTTPKETAPTTPKEPAPT--TPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSP 780
Query: 298 KHGLPDVGL-----AAEDSKRDPLCPRRAEPC---PRVPATPR-RMSDPPLSTMPTAPGL 348
P++ A E+S ++P P P P + T + + ++ L T P
Sbjct: 781 DESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETT-T 839
Query: 349 RKPPCFRESASPSPEPWTPGHGACSTSSAAIMAT--ATSRNCDKLKSFHLSPRGPPTSEP 406
P +E+A+ + E T +T+ T T LK+ L+P+ T +
Sbjct: 840 AAPKMTKETATTT-EKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKT 898
Query: 407 PPVPA--NKPKFLKIAEEDPPREAAMPGLFVPPVAPRPPALKLPVPEAMARPAVLPRPEK 464
NKP+ E P++ A P P+ P P + +P +PR K
Sbjct: 899 ITTTEIMNKPE-----ETAKPKDRATNSKATTP-KPQKPTKAPKKPTSTKKPKTMPRVRK 952
Query: 465 PQ 466
P+
Sbjct: 953 PK 954
Score = 34.3 bits (77), Expect = 0.35
Identities = 38/172 (22%), Positives = 54/172 (31%), Gaps = 25/172 (14%)
Query: 343 PTAPGLRKPPCFRESASPSPEPWTPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGP- 401
PT+ L KP E+ + P TP +T T +KS +P+ P
Sbjct: 230 PTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPA 289
Query: 402 -----------------PTSEPPPVPANKPKFLKIAEEDPPREAAMPGLFVPPVAPRPPA 444
T EP P +P E P + P P P P
Sbjct: 290 PTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAP---TTPKEPAPTT 346
Query: 445 LKLPVPEAMARPAVL----PRPEKPQLPHLQRSPPDGQSFRSFSFEKPRQPS 492
K P P PA P P P+ P P + + + P++P+
Sbjct: 347 PKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPA 398
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 57.4 bits (137), Expect = 4e-08
Identities = 68/314 (21%), Positives = 100/314 (31%), Gaps = 34/314 (10%)
Query: 214 ERPVDISLSPYPTDNEDYEHDDEDDSYLEPDSPEPGRLEDALMHPPAYPPPPVPTPRKPA 273
+ P ++ PT ++ + P P P ++ P P P PT K
Sbjct: 323 KEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPA---PTTPKEPAPTTTKEP 379
Query: 274 FSDMPRAHSFTSKGPGPLLPPPPPKHGLPDVGLAAEDSKRDPLCPRRAEPCPRVPATPRR 333
++ T K P P P P A + ++P EP P P P
Sbjct: 380 APTTTKSAPTTPKEPAPTTPKKP-----------APTTPKEPAPTTPKEPTPTTPKEPAP 428
Query: 334 MSDPPLST-----MPTAPGLRKPPCFRESA-----------SPSPEPWTPGHGACSTSSA 377
+ P T PTAP P +E A + P P TP A +T+ +
Sbjct: 429 TTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKS 488
Query: 378 AIMATATSRNCDKLKSFHLSPRGP-PTSEPPPVPANKPKFLKIAEEDPPREAAMPGLFVP 436
A T KS +P+ P PT+ P P + + P
Sbjct: 489 A-PTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTT 547
Query: 437 PVAPRPPALKLPVPEAMARPA-VLPRPEKPQLPHLQRSPPDGQSFRSFSFEKPRQPSQAD 495
P P P K P P PA P+ P P + +P + + EKP + +
Sbjct: 548 PKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPK-KLTPTTPEKLAPTTPEKPAPTTPEE 606
Query: 496 TGGDDSDEDYEKVP 509
+E P
Sbjct: 607 LAPTTPEEPTPTTP 620
Score = 52.8 bits (125), Expect = 9e-07
Identities = 67/267 (25%), Positives = 91/267 (34%), Gaps = 28/267 (10%)
Query: 223 PYPTDNEDYEHDD-EDDSYLEPDSPEPGRLEDALMHPPAYPPPPVP------TPRKPAFS 275
P PT E+ E+ + P+ P P + A + P P P P TP++PA +
Sbjct: 599 PAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPT 658
Query: 276 DMPRAHSFTSKGPGP--LLPPPPPKHGLPDVGLAAEDSKRDPLCPRRAEPCPRVP-ATPR 332
T KG P L P P P A + ++P +P P P T
Sbjct: 659 TPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAP 718
Query: 333 RMSDPPLSTMPTAPGLRKPPCFRESASPSPEPWTPGHGACSTSSAAIMATATSRNCDKLK 392
P T P P P + P P TP A + TS DK
Sbjct: 719 TTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDK-- 776
Query: 393 SFHLSPRGP----PTSEPPPVPANKPKFLKIAEEDPPREAAMPGLFVPPVAPRPPAL-KL 447
+P P PT+ P P K E PP + + P P + K
Sbjct: 777 ---PAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTS--EVSTPTTTKEPTTIHKS 831
Query: 448 P---VPEAMARP---AVLPRPEKPQLP 468
P PE A P A+ P++P +P
Sbjct: 832 PDESTPELSAEPTPKALENSPKEPGVP 858
Score = 48.5 bits (114), Expect = 2e-05
Identities = 72/311 (23%), Positives = 96/311 (30%), Gaps = 42/311 (13%)
Query: 242 EPDSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPPKHGL 301
EP P PA P P P P + T P L P P K
Sbjct: 542 EPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAP 601
Query: 302 PDVGLAAEDSKRDPLCPRRAEPCPRVP--ATPRRMSDP----PLSTMPTAPGLRKPPCFR 355
A + +P EP P P A P +P P PT P P +
Sbjct: 602 TTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPK 661
Query: 356 ESASPSPE-----------PWTPGHGACSTSSAAIMATATSRNCDK------LKSFHLSP 398
E+A +P+ P TP A + TS CDK + +P
Sbjct: 662 ETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTP 721
Query: 399 RGP-PTSEPPPVP----ANKPKFLKIAEEDPPREAAMPGLFVPPVA----------PRPP 443
+ P PT+ P P P LK P++ A P P P P
Sbjct: 722 KEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPA-PKELAPTTTKGPTSTTSDKPAPT 780
Query: 444 ALKLPVPEAMARPAVLPRPEKPQLPHLQRSPPDGQSFRSFSFEKPRQPSQADTGGDDSDE 503
K P PA P K P +PP S S + ++P+ D+S
Sbjct: 781 TPKETAPTTPKEPA--PTTPKKPAPTTPETPPPTTSEVS-TPTTTKEPTTIHKSPDESTP 837
Query: 504 DYEKVPLPNSV 514
+ P P ++
Sbjct: 838 ELSAEPTPKAL 848
Score = 44.3 bits (103), Expect = 3e-04
Identities = 51/202 (25%), Positives = 70/202 (34%), Gaps = 32/202 (15%)
Query: 291 LLPPPPPKHGLPDVGLAAEDSKRDPLCPRRAEPCPRVP-----ATPRRMSDPPLSTMPTA 345
+L P PK AE + + P EP P P TP+ + + + PT
Sbjct: 286 VLAKPTPK---------AETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTT 336
Query: 346 PGLRKP------PCFRESASPS----PEPWTPGHGACSTSSAAIMATATSRNCDKLKSFH 395
P P P + +P+ P P TP A +T+ T S +
Sbjct: 337 PKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAP 396
Query: 396 LSPRGP-PTS--EPPPVPANKPKFLKIAEEDPPREAAMPGLFVPPVAPRPPALKLPVPEA 452
+P+ P PT+ EP P +P E P + P P P P A K P P
Sbjct: 397 TTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAP---TTPKEPAPTAPKKPAPTT 453
Query: 453 MARPAVLPRPEKPQLPHLQRSP 474
PA P K P + P
Sbjct: 454 PKEPA--PTTPKEPAPTTTKEP 473
Score = 36.6 bits (83), Expect = 0.070
Identities = 56/242 (23%), Positives = 89/242 (36%), Gaps = 29/242 (11%)
Query: 244 DSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPP------P 297
D P P ++ P P P TP+KPA + TS+ P P P
Sbjct: 775 DKPAPTTPKETAPTTPKEPAPT--TPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSP 832
Query: 298 KHGLPDVGL-----AAEDSKRDPLCPRRAEPC---PRVPATPR-RMSDPPLSTMPTAPGL 348
P++ A E+S ++P P P P + T + + ++ L T P
Sbjct: 833 DESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETT-T 891
Query: 349 RKPPCFRESASPSPEPWTPGHGACSTSSAAIMAT--ATSRNCDKLKSFHLSPRGPPTSEP 406
P +E+A+ + E T +T+ T T LK+ L+P+ T +
Sbjct: 892 AAPKMTKETATTT-EKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKT 950
Query: 407 PPVPA--NKPKFLKIAEEDPPREAAMPGLFVPPVAPRPPALKLPVPEAMARPAVLPRPEK 464
NKP+ E P++ A P P+ P P + +P +PR K
Sbjct: 951 ITTTEIMNKPE-----ETAKPKDRATNSKATTP-KPQKPTKAPKKPTSTKKPKTMPRVRK 1004
Query: 465 PQ 466
P+
Sbjct: 1005 PK 1006
Score = 34.3 bits (77), Expect = 0.35
Identities = 38/172 (22%), Positives = 54/172 (31%), Gaps = 25/172 (14%)
Query: 343 PTAPGLRKPPCFRESASPSPEPWTPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGP- 401
PT+ L KP E+ + P TP +T T +KS +P+ P
Sbjct: 282 PTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPA 341
Query: 402 -----------------PTSEPPPVPANKPKFLKIAEEDPPREAAMPGLFVPPVAPRPPA 444
T EP P +P E P + P P P P
Sbjct: 342 PTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAP---TTPKEPAPTT 398
Query: 445 LKLPVPEAMARPAVL----PRPEKPQLPHLQRSPPDGQSFRSFSFEKPRQPS 492
K P P PA P P P+ P P + + + P++P+
Sbjct: 399 PKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPA 450
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 57.4 bits (137), Expect = 4e-08
Identities = 68/314 (21%), Positives = 100/314 (31%), Gaps = 34/314 (10%)
Query: 214 ERPVDISLSPYPTDNEDYEHDDEDDSYLEPDSPEPGRLEDALMHPPAYPPPPVPTPRKPA 273
+ P ++ PT ++ + P P P ++ P P P PT K
Sbjct: 364 KEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPA---PTTPKEPAPTTTKEP 420
Query: 274 FSDMPRAHSFTSKGPGPLLPPPPPKHGLPDVGLAAEDSKRDPLCPRRAEPCPRVPATPRR 333
++ T K P P P P A + ++P EP P P P
Sbjct: 421 APTTTKSAPTTPKEPAPTTPKKP-----------APTTPKEPAPTTPKEPTPTTPKEPAP 469
Query: 334 MSDPPLST-----MPTAPGLRKPPCFRESA-----------SPSPEPWTPGHGACSTSSA 377
+ P T PTAP P +E A + P P TP A +T+ +
Sbjct: 470 TTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKS 529
Query: 378 AIMATATSRNCDKLKSFHLSPRGP-PTSEPPPVPANKPKFLKIAEEDPPREAAMPGLFVP 436
A T KS +P+ P PT+ P P + + P
Sbjct: 530 A-PTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTT 588
Query: 437 PVAPRPPALKLPVPEAMARPA-VLPRPEKPQLPHLQRSPPDGQSFRSFSFEKPRQPSQAD 495
P P P K P P PA P+ P P + +P + + EKP + +
Sbjct: 589 PKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPK-KLTPTTPEKLAPTTPEKPAPTTPEE 647
Query: 496 TGGDDSDEDYEKVP 509
+E P
Sbjct: 648 LAPTTPEEPTPTTP 661
Score = 52.8 bits (125), Expect = 9e-07
Identities = 67/267 (25%), Positives = 91/267 (34%), Gaps = 28/267 (10%)
Query: 223 PYPTDNEDYEHDD-EDDSYLEPDSPEPGRLEDALMHPPAYPPPPVP------TPRKPAFS 275
P PT E+ E+ + P+ P P + A + P P P P TP++PA +
Sbjct: 640 PAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPT 699
Query: 276 DMPRAHSFTSKGPGP--LLPPPPPKHGLPDVGLAAEDSKRDPLCPRRAEPCPRVP-ATPR 332
T KG P L P P P A + ++P +P P P T
Sbjct: 700 TPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAP 759
Query: 333 RMSDPPLSTMPTAPGLRKPPCFRESASPSPEPWTPGHGACSTSSAAIMATATSRNCDKLK 392
P T P P P + P P TP A + TS DK
Sbjct: 760 TTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDK-- 817
Query: 393 SFHLSPRGP----PTSEPPPVPANKPKFLKIAEEDPPREAAMPGLFVPPVAPRPPAL-KL 447
+P P PT+ P P K E PP + + P P + K
Sbjct: 818 ---PAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTS--EVSTPTTTKEPTTIHKS 872
Query: 448 P---VPEAMARP---AVLPRPEKPQLP 468
P PE A P A+ P++P +P
Sbjct: 873 PDESTPELSAEPTPKALENSPKEPGVP 899
Score = 48.5 bits (114), Expect = 2e-05
Identities = 72/311 (23%), Positives = 96/311 (30%), Gaps = 42/311 (13%)
Query: 242 EPDSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPPKHGL 301
EP P PA P P P P + T P L P P K
Sbjct: 583 EPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAP 642
Query: 302 PDVGLAAEDSKRDPLCPRRAEPCPRVP--ATPRRMSDP----PLSTMPTAPGLRKPPCFR 355
A + +P EP P P A P +P P PT P P +
Sbjct: 643 TTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPK 702
Query: 356 ESASPSPE-----------PWTPGHGACSTSSAAIMATATSRNCDK------LKSFHLSP 398
E+A +P+ P TP A + TS CDK + +P
Sbjct: 703 ETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTP 762
Query: 399 RGP-PTSEPPPVP----ANKPKFLKIAEEDPPREAAMPGLFVPPVA----------PRPP 443
+ P PT+ P P P LK P++ A P P P P
Sbjct: 763 KEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPA-PKELAPTTTKGPTSTTSDKPAPT 821
Query: 444 ALKLPVPEAMARPAVLPRPEKPQLPHLQRSPPDGQSFRSFSFEKPRQPSQADTGGDDSDE 503
K P PA P K P +PP S S + ++P+ D+S
Sbjct: 822 TPKETAPTTPKEPA--PTTPKKPAPTTPETPPPTTSEVS-TPTTTKEPTTIHKSPDESTP 878
Query: 504 DYEKVPLPNSV 514
+ P P ++
Sbjct: 879 ELSAEPTPKAL 889
Score = 44.3 bits (103), Expect = 3e-04
Identities = 51/202 (25%), Positives = 70/202 (34%), Gaps = 32/202 (15%)
Query: 291 LLPPPPPKHGLPDVGLAAEDSKRDPLCPRRAEPCPRVP-----ATPRRMSDPPLSTMPTA 345
+L P PK AE + + P EP P P TP+ + + + PT
Sbjct: 327 VLAKPTPK---------AETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTT 377
Query: 346 PGLRKP------PCFRESASPS----PEPWTPGHGACSTSSAAIMATATSRNCDKLKSFH 395
P P P + +P+ P P TP A +T+ T S +
Sbjct: 378 PKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAP 437
Query: 396 LSPRGP-PTS--EPPPVPANKPKFLKIAEEDPPREAAMPGLFVPPVAPRPPALKLPVPEA 452
+P+ P PT+ EP P +P E P + P P P P A K P P
Sbjct: 438 TTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAP---TTPKEPAPTAPKKPAPTT 494
Query: 453 MARPAVLPRPEKPQLPHLQRSP 474
PA P K P + P
Sbjct: 495 PKEPA--PTTPKEPAPTTTKEP 514
Score = 36.6 bits (83), Expect = 0.070
Identities = 56/242 (23%), Positives = 89/242 (36%), Gaps = 29/242 (11%)
Query: 244 DSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPP------P 297
D P P ++ P P P TP+KPA + TS+ P P P
Sbjct: 816 DKPAPTTPKETAPTTPKEPAPT--TPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSP 873
Query: 298 KHGLPDVGL-----AAEDSKRDPLCPRRAEPC---PRVPATPR-RMSDPPLSTMPTAPGL 348
P++ A E+S ++P P P P + T + + ++ L T P
Sbjct: 874 DESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETT-T 932
Query: 349 RKPPCFRESASPSPEPWTPGHGACSTSSAAIMAT--ATSRNCDKLKSFHLSPRGPPTSEP 406
P +E+A+ + E T +T+ T T LK+ L+P+ T +
Sbjct: 933 AAPKMTKETATTT-EKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKT 991
Query: 407 PPVPA--NKPKFLKIAEEDPPREAAMPGLFVPPVAPRPPALKLPVPEAMARPAVLPRPEK 464
NKP+ E P++ A P P+ P P + +P +PR K
Sbjct: 992 ITTTEIMNKPE-----ETAKPKDRATNSKATTP-KPQKPTKAPKKPTSTKKPKTMPRVRK 1045
Query: 465 PQ 466
P+
Sbjct: 1046 PK 1047
Score = 34.3 bits (77), Expect = 0.35
Identities = 38/172 (22%), Positives = 54/172 (31%), Gaps = 25/172 (14%)
Query: 343 PTAPGLRKPPCFRESASPSPEPWTPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGP- 401
PT+ L KP E+ + P TP +T T +KS +P+ P
Sbjct: 323 PTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPA 382
Query: 402 -----------------PTSEPPPVPANKPKFLKIAEEDPPREAAMPGLFVPPVAPRPPA 444
T EP P +P E P + P P P P
Sbjct: 383 PTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAP---TTPKEPAPTT 439
Query: 445 LKLPVPEAMARPAVL----PRPEKPQLPHLQRSPPDGQSFRSFSFEKPRQPS 492
K P P PA P P P+ P P + + + P++P+
Sbjct: 440 PKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPA 491
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.134 0.424
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,688,468
Number of Sequences: 37866
Number of extensions: 2415887
Number of successful extensions: 22281
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 229
Number of HSP's successfully gapped in prelim test: 1366
Number of HSP's that attempted gapping in prelim test: 12095
Number of HSP's gapped (non-prelim): 6747
length of query: 618
length of database: 18,247,518
effective HSP length: 108
effective length of query: 510
effective length of database: 14,157,990
effective search space: 7220574900
effective search space used: 7220574900
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.