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Search of human proteins with 11545761
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|11545761 potassium channel, subfamily K, member 12 [Homo
sapiens]
(430 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|11545761 potassium channel, subfamily K, member 12 [Homo sapi... 865 0.0
gi|16306555 potassium channel, subfamily K, member 13 [Homo sapi... 521 e-148
gi|4758624 potassium channel, subfamily K, member 6 [Homo sapiens] 115 1e-25
gi|4504849 potassium channel, subfamily K, member 3 [Homo sapiens] 113 4e-25
gi|14149764 potassium channel, subfamily K, member 16 isoform 2 ... 111 1e-24
gi|14589851 potassium channel, subfamily K, member 2 isoform b [... 108 7e-24
gi|126365795 potassium channel, subfamily K, member 2 isoform c ... 108 7e-24
gi|62912487 potassium channel, subfamily K, member 2 isoform a [... 108 7e-24
gi|4504847 potassium channel, subfamily K, member 1 [Homo sapiens] 105 8e-23
gi|205360983 potassium channel, subfamily K, member 16 isoform 3... 105 8e-23
gi|11641275 potassium family, subfamily K, member 15 [Homo sapiens] 105 8e-23
gi|20143946 potassium channel, subfamily K, member 10 isoform 3 ... 104 2e-22
gi|20143944 potassium channel, subfamily K, member 10 isoform 2 ... 104 2e-22
gi|10863961 potassium channel, subfamily K, member 10 isoform 1 ... 104 2e-22
gi|7706135 potassium channel, subfamily K, member 9 [Homo sapiens] 102 5e-22
gi|15718767 TRAAK [Homo sapiens] 100 3e-21
gi|205360973 potassium channel, subfamily K, member 16 isoform 4... 99 1e-20
gi|205360971 potassium channel, subfamily K, member 16 isoform 1... 99 1e-20
gi|4504851 potassium channel, subfamily K, member 5 [Homo sapiens] 92 7e-19
gi|17025230 potassium channel, subfamily K, member 17 isoform 1 ... 83 4e-16
gi|205361107 potassium channel, subfamily K, member 17 isoform 2... 76 7e-14
gi|16118231 potassium channel, subfamily K, member 7 isoform A [... 71 2e-12
gi|5031821 potassium channel, subfamily K, member 7 isoform C [H... 69 6e-12
gi|16118235 potassium channel, subfamily K, member 7 isoform B [... 69 6e-12
gi|16118233 potassium channel, subfamily K, member 7 isoform B [... 69 6e-12
gi|41349443 potassium channel, subfamily T, member 2 [Homo sapiens] 41 0.002
gi|32469495 potassium channel, subfamily K, member 18 [Homo sapi... 40 0.003
gi|240255505 potassium channel, subfamily T, member 1 [Homo sapi... 36 0.059
gi|33620725 calcipressin 1 isoform a [Homo sapiens] 34 0.22
gi|27436981 potassium voltage-gated channel, Shal-related subfam... 32 1.5
>gi|11545761 potassium channel, subfamily K, member 12 [Homo
sapiens]
Length = 430
Score = 865 bits (2234), Expect = 0.0
Identities = 430/430 (100%), Positives = 430/430 (100%)
Query: 1 MSSRSPRPPPRRSRRRLPRPSCCCCCCRRSHLNEDTGRFVLLAALIGLYLVAGATVFSAL 60
MSSRSPRPPPRRSRRRLPRPSCCCCCCRRSHLNEDTGRFVLLAALIGLYLVAGATVFSAL
Sbjct: 1 MSSRSPRPPPRRSRRRLPRPSCCCCCCRRSHLNEDTGRFVLLAALIGLYLVAGATVFSAL 60
Query: 61 ESPGEAEARARWGATLRNFSAAHGVAEPELRAFLRHYEAALAAGVRADALRPRWDFPGAF 120
ESPGEAEARARWGATLRNFSAAHGVAEPELRAFLRHYEAALAAGVRADALRPRWDFPGAF
Sbjct: 61 ESPGEAEARARWGATLRNFSAAHGVAEPELRAFLRHYEAALAAGVRADALRPRWDFPGAF 120
Query: 121 YFVGTVVSTIGFGMTTPATVGGKAFLIAYGLFGCAGTILFFNLFLERIISLLAFIMRACR 180
YFVGTVVSTIGFGMTTPATVGGKAFLIAYGLFGCAGTILFFNLFLERIISLLAFIMRACR
Sbjct: 121 YFVGTVVSTIGFGMTTPATVGGKAFLIAYGLFGCAGTILFFNLFLERIISLLAFIMRACR 180
Query: 181 ERQLRRSGLLPATFRRGSALSEADSLAGWKPSVYHVLLILGLFAVLLSCCASAMYTSVEG 240
ERQLRRSGLLPATFRRGSALSEADSLAGWKPSVYHVLLILGLFAVLLSCCASAMYTSVEG
Sbjct: 181 ERQLRRSGLLPATFRRGSALSEADSLAGWKPSVYHVLLILGLFAVLLSCCASAMYTSVEG 240
Query: 241 WDYVDSLYFCFVTFSTIGFGDLVSSQHAAYRNQGLYRLGNFLFILLGVCCIYSLFNVISI 300
WDYVDSLYFCFVTFSTIGFGDLVSSQHAAYRNQGLYRLGNFLFILLGVCCIYSLFNVISI
Sbjct: 241 WDYVDSLYFCFVTFSTIGFGDLVSSQHAAYRNQGLYRLGNFLFILLGVCCIYSLFNVISI 300
Query: 301 LIKQVLNWMLRKLSCRCCARCCPAPGAPLARRNAITPGSRLRRRLAALGADPAARDSDAE 360
LIKQVLNWMLRKLSCRCCARCCPAPGAPLARRNAITPGSRLRRRLAALGADPAARDSDAE
Sbjct: 301 LIKQVLNWMLRKLSCRCCARCCPAPGAPLARRNAITPGSRLRRRLAALGADPAARDSDAE 360
Query: 361 GRRLSGELISMRDLTASNKVSLALLQKQLSETANGYPRSVCVNTRQNGFSGGVGALGIMN 420
GRRLSGELISMRDLTASNKVSLALLQKQLSETANGYPRSVCVNTRQNGFSGGVGALGIMN
Sbjct: 361 GRRLSGELISMRDLTASNKVSLALLQKQLSETANGYPRSVCVNTRQNGFSGGVGALGIMN 420
Query: 421 NRLAETSASR 430
NRLAETSASR
Sbjct: 421 NRLAETSASR 430
>gi|16306555 potassium channel, subfamily K, member 13 [Homo
sapiens]
Length = 408
Score = 521 bits (1341), Expect = e-148
Identities = 262/400 (65%), Positives = 304/400 (76%), Gaps = 3/400 (0%)
Query: 31 HLNEDTGRFVLLAALIGLYLVAGATVFSALESPGEAEARARWGATLRNFSAAHGVAEPEL 90
HLNED RF+LLAALI LYL+ GA VFSALE E +A+ RW L NFS H ++ EL
Sbjct: 12 HLNEDNARFLLLAALIVLYLLGGAAVFSALELAHERQAKQRWEERLANFSRGHNLSRDEL 71
Query: 91 RAFLRHYEAALAAGVRADALRPRWDFPGAFYFVGTVVSTIGFGMTTPATVGGKAFLIAYG 150
R FLRHYE A AG+R D +RPRWDF GAFYFVGTVVSTIGFGMTTPATVGGK FLI YG
Sbjct: 72 RGFLRHYEEATRAGIRVDNVRPRWDFTGAFYFVGTVVSTIGFGMTTPATVGGKIFLIFYG 131
Query: 151 LFGCAGTILFFNLFLERIISLLAFIMRACRERQLRRSGLLPATFRRGSALSEADSLAGWK 210
L GC+ TILFFNLFLER+I+++A+IM++C +RQLRR G LP + + E DSLAGWK
Sbjct: 132 LVGCSSTILFFNLFLERLITIIAYIMKSCHQRQLRRRGALPQESLKDAGQCEVDSLAGWK 191
Query: 211 PSVYHVLLILGLFAVLLSCCASAMYTSVEGWDYVDSLYFCFVTFSTIGFGDLVSSQHAAY 270
PSVY+V+LIL ++L+SCCASAMYT +EGW Y DSLYFCFV FSTIGFGDLVSSQ+A Y
Sbjct: 192 PSVYYVMLILCTASILISCCASAMYTPIEGWSYFDSLYFCFVAFSTIGFGDLVSSQNAHY 251
Query: 271 RNQGLYRLGNFLFILLGVCCIYSLFNVISILIKQVLNWMLRKLSCRCCARCCPAPGAPLA 330
+QGLYR NF+FIL+GVCCIYSLFNVISILIKQ LNW+LRK+ CC +C G +
Sbjct: 252 ESQGLYRFANFVFILMGVCCIYSLFNVISILIKQSLNWILRKMDSGCCPQC--QRGLLRS 309
Query: 331 RRNAITPGSRLRRRLAALGADPAARDSDAEGRRLSGELISMRDLTASNKVSLALLQKQLS 390
RRN + PGS R ++ D A +SD +GRRLSGE+ISM+DL A+NK SLA+LQKQLS
Sbjct: 310 RRNVVMPGSVRNRCNISIETDGVA-ESDTDGRRLSGEMISMKDLLAANKASLAILQKQLS 368
Query: 391 ETANGYPRSVCVNTRQNGFSGGVGALGIMNNRLAETSASR 430
E ANG P R N FSGGVGA IMNNRLAETS R
Sbjct: 369 EMANGCPHQTSTLARDNEFSGGVGAFAIMNNRLAETSGDR 408
>gi|4758624 potassium channel, subfamily K, member 6 [Homo sapiens]
Length = 313
Score = 115 bits (287), Expect = 1e-25
Identities = 80/259 (30%), Positives = 120/259 (46%), Gaps = 38/259 (14%)
Query: 44 ALIGLYLVAGATVFSALESPGEAEARARWGATLRN--FSAAHGVAEPELRAFLRHYEAA- 100
A YLV GA + + LE P EA RA TLR + VA P L AF+ AA
Sbjct: 12 AAYAAYLVLGALLVARLEGPHEARLRAEL-ETLRAQLLQRSPCVAAPALDAFVERVLAAG 70
Query: 101 -------LAAGVRADALRPRWDFPGAFYFVGTVVSTIGFGMTTPATVGGKAFLIAYGLFG 153
A A+A P WDF A +F T+++T+G+G TTP T GKAF IA+ L G
Sbjct: 71 RLGRVVLANASGSANASDPAWDFASALFFASTLITTVGYGYTTPLTDAGKAFSIAFALLG 130
Query: 154 CAGTILFFNLFLERIISLLAFIMRACRERQLRRSGLLPATFRRGSALSEADSLAGWKP-- 211
T+L +R+ LL + LS GW P
Sbjct: 131 VPTTMLLLTASAQRLSLLLTHV-----------------------PLSWLSMRWGWDPRR 167
Query: 212 -SVYHVLLILGLFAVLLSCCASAMYTSV-EGWDYVDSLYFCFVTFSTIGFGDLVSSQHAA 269
+ +H++ +LG+ + + ++ + E W ++D+ YFCF++ STIG GD V +
Sbjct: 168 AACWHLVALLGVVVTVCFLVPAVIFAHLEEAWSFLDAFYFCFISLSTIGLGDYVPGEAPG 227
Query: 270 YRNQGLYRLGNFLFILLGV 288
+ LY++ +++ LG+
Sbjct: 228 QPYRALYKVLVTVYLFLGL 246
>gi|4504849 potassium channel, subfamily K, member 3 [Homo sapiens]
Length = 394
Score = 113 bits (282), Expect = 4e-25
Identities = 74/253 (29%), Positives = 125/253 (49%), Gaps = 31/253 (12%)
Query: 49 YLVAGATVFSALESPGEAEARARWGATLRNFSAAHGVAEPELRAFLRHYEAALAAGVRAD 108
YL+ GA VF ALES E R R + A + +++ R + ++
Sbjct: 18 YLLVGAAVFDALESEPELIERQRLELRQQELRARYNLSQGGYEELER-----VVLRLKPH 72
Query: 109 ALRPRWDFPGAFYFVGTVVSTIGFGMTTPATVGGKAFLIAYGLFGCAGTILFFNLFLERI 168
+W F G+FYF TV++TIG+G P+T GGK F + Y L G T++ F ERI
Sbjct: 73 KAGVQWRFAGSFYFAITVITTIGYGHAAPSTDGGKVFCMFYALLGIPLTLVMFQSLGERI 132
Query: 169 ISLLAFIMRACRERQLRRSGLLPATFRRGSALSEAD-SLAGWKPSVYHVLLILGLFAVLL 227
+L+ +++ ++G + AD S+A ++++G F+ +
Sbjct: 133 NTLVRYLLHRA---------------KKGLGMRRADVSMAN--------MVLIGFFSCIS 169
Query: 228 S-CCASAMYTSVEGWDYVDSLYFCFVTFSTIGFGDLVSSQ-HAAYRNQGLYRLGNFLFIL 285
+ C +A ++ E W + + Y+CF+T +TIGFGD V+ Q A + Q Y +F++IL
Sbjct: 170 TLCIGAAAFSHYEHWTFFQAYYYCFITLTTIGFGDYVALQKDQALQTQPQYVAFSFVYIL 229
Query: 286 LGVCCIYSLFNVI 298
G+ I + N++
Sbjct: 230 TGLTVIGAFLNLV 242
>gi|14149764 potassium channel, subfamily K, member 16 isoform 2
[Homo sapiens]
Length = 309
Score = 111 bits (278), Expect = 1e-24
Identities = 95/326 (29%), Positives = 145/326 (44%), Gaps = 38/326 (11%)
Query: 20 PSCCCCCCRRSHLNEDTGRFVLLAALIGLYLVAGATVFSALESPGEAEARARWGATLRNF 79
PS C C GR + L YL+ GAT+F LE EA++R ++ F
Sbjct: 2 PSAGLCSCWG-------GRVLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRF 54
Query: 80 SAAHGVAEP-ELRAFLRHYEAALAAGV--RADALRP-RWDFPGAFYFVGTVVSTIGFGMT 135
+ + + F++ A GV + ++ P WDF +F+F GTVV+TIG+G
Sbjct: 55 LENYTCLDQWAMEQFVQVIMEAWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNL 114
Query: 136 TPATVGGKAFLIAYGLFGCAGTILFFNLFLERIISLLAFIMRACRERQLRRSGLLPATFR 195
P+T G+ F + Y L G ++F N + + LA I R E + RRS +L
Sbjct: 115 APSTEAGQVFCVFYALLGIPLNVIFLNHLGTGLRAHLAAIERW--EDRPRRSQVLQVL-- 170
Query: 196 RGSALSEADSLAGWKPSVYHVLLILGLFAVLLSCCASAMYTSVEGWDYVDSLYFCFVTFS 255
G AL L LG +L+ +++ VEGW + + YF F+T S
Sbjct: 171 -GLAL----------------FLTLGTLVILIF--PPMVFSHVEGWSFSEGFYFAFITLS 211
Query: 256 TIGFGDLVSSQHAAYRNQGLYRLGNFLFILLGVCCIYSLFNVISILIKQVLNWMLRKLSC 315
TIGFGD V + +YR ++ILLG+ + + + +L+ + L L
Sbjct: 212 TIGFGDYVVGTDPSKHYISVYRSLAAIWILLGLAWLALILPLGPLLLHRCCQLWLLSLRQ 271
Query: 316 RCCARCCPA----PGAPLARRNAITP 337
C A+ P G+ AR +TP
Sbjct: 272 GCGAKAAPGRRPRRGSTAARGVQVTP 297
>gi|14589851 potassium channel, subfamily K, member 2 isoform b
[Homo sapiens]
Length = 411
Score = 108 bits (271), Expect = 7e-24
Identities = 78/264 (29%), Positives = 122/264 (46%), Gaps = 34/264 (12%)
Query: 45 LIGLYLVAGATVFSALESPGEAEARARWGATLRNFSAAHG-VAEPELRAFLRHYEAALAA 103
++ LYL+ GATVF ALE P E R + F + H V EL ++ AA+ A
Sbjct: 53 VVVLYLIIGATVFKALEQPHEISQRTTIVIQKQTFISQHSCVNSTELDELIQQIVAAINA 112
Query: 104 GV----RADALRPRWDFPGAFYFVGTVVSTIGFGMTTPATVGGKAFLIAYGLFGCAGTIL 159
G+ WD +F+F GTV++TIGFG +P T GGK F I Y L G
Sbjct: 113 GIIPLGNTSNQISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLG------ 166
Query: 160 FFNLFLERIISLLAFIMRACRERQLRRSGLLPATFRRGSALSEADSLAGWKPSVYHVLLI 219
I L F++ ++ L F +G A E D+ W S + +I
Sbjct: 167 ---------IPLFGFLLAGVGDQ-------LGTIFGKGIAKVE-DTFIKWNVSQTKIRII 209
Query: 220 LGLFAVLLSC-----CASAMYTSVEGWDYVDSLYFCFVTFSTIGFGDLVSSQHAAYRNQG 274
+ +L C + ++ +EGW +D++YF +T +TIGFGD V+ +
Sbjct: 210 STIIFILFGCVLFVALPAIIFKHIEGWSALDAIYFVVITLTTIGFGDYVAG-GSDIEYLD 268
Query: 275 LYRLGNFLFILLGVCCIYSLFNVI 298
Y+ + +IL+G+ ++ ++I
Sbjct: 269 FYKPVVWFWILVGLAYFAAVLSMI 292
>gi|126365795 potassium channel, subfamily K, member 2 isoform c
[Homo sapiens]
Length = 426
Score = 108 bits (271), Expect = 7e-24
Identities = 78/264 (29%), Positives = 122/264 (46%), Gaps = 34/264 (12%)
Query: 45 LIGLYLVAGATVFSALESPGEAEARARWGATLRNFSAAHG-VAEPELRAFLRHYEAALAA 103
++ LYL+ GATVF ALE P E R + F + H V EL ++ AA+ A
Sbjct: 68 VVVLYLIIGATVFKALEQPHEISQRTTIVIQKQTFISQHSCVNSTELDELIQQIVAAINA 127
Query: 104 GV----RADALRPRWDFPGAFYFVGTVVSTIGFGMTTPATVGGKAFLIAYGLFGCAGTIL 159
G+ WD +F+F GTV++TIGFG +P T GGK F I Y L G
Sbjct: 128 GIIPLGNTSNQISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLG------ 181
Query: 160 FFNLFLERIISLLAFIMRACRERQLRRSGLLPATFRRGSALSEADSLAGWKPSVYHVLLI 219
I L F++ ++ L F +G A E D+ W S + +I
Sbjct: 182 ---------IPLFGFLLAGVGDQ-------LGTIFGKGIAKVE-DTFIKWNVSQTKIRII 224
Query: 220 LGLFAVLLSC-----CASAMYTSVEGWDYVDSLYFCFVTFSTIGFGDLVSSQHAAYRNQG 274
+ +L C + ++ +EGW +D++YF +T +TIGFGD V+ +
Sbjct: 225 STIIFILFGCVLFVALPAIIFKHIEGWSALDAIYFVVITLTTIGFGDYVAG-GSDIEYLD 283
Query: 275 LYRLGNFLFILLGVCCIYSLFNVI 298
Y+ + +IL+G+ ++ ++I
Sbjct: 284 FYKPVVWFWILVGLAYFAAVLSMI 307
>gi|62912487 potassium channel, subfamily K, member 2 isoform a
[Homo sapiens]
Length = 422
Score = 108 bits (271), Expect = 7e-24
Identities = 78/264 (29%), Positives = 122/264 (46%), Gaps = 34/264 (12%)
Query: 45 LIGLYLVAGATVFSALESPGEAEARARWGATLRNFSAAHG-VAEPELRAFLRHYEAALAA 103
++ LYL+ GATVF ALE P E R + F + H V EL ++ AA+ A
Sbjct: 64 VVVLYLIIGATVFKALEQPHEISQRTTIVIQKQTFISQHSCVNSTELDELIQQIVAAINA 123
Query: 104 GV----RADALRPRWDFPGAFYFVGTVVSTIGFGMTTPATVGGKAFLIAYGLFGCAGTIL 159
G+ WD +F+F GTV++TIGFG +P T GGK F I Y L G
Sbjct: 124 GIIPLGNTSNQISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLG------ 177
Query: 160 FFNLFLERIISLLAFIMRACRERQLRRSGLLPATFRRGSALSEADSLAGWKPSVYHVLLI 219
I L F++ ++ L F +G A E D+ W S + +I
Sbjct: 178 ---------IPLFGFLLAGVGDQ-------LGTIFGKGIAKVE-DTFIKWNVSQTKIRII 220
Query: 220 LGLFAVLLSC-----CASAMYTSVEGWDYVDSLYFCFVTFSTIGFGDLVSSQHAAYRNQG 274
+ +L C + ++ +EGW +D++YF +T +TIGFGD V+ +
Sbjct: 221 STIIFILFGCVLFVALPAIIFKHIEGWSALDAIYFVVITLTTIGFGDYVAG-GSDIEYLD 279
Query: 275 LYRLGNFLFILLGVCCIYSLFNVI 298
Y+ + +IL+G+ ++ ++I
Sbjct: 280 FYKPVVWFWILVGLAYFAAVLSMI 303
>gi|4504847 potassium channel, subfamily K, member 1 [Homo sapiens]
Length = 336
Score = 105 bits (262), Expect = 8e-23
Identities = 83/258 (32%), Positives = 125/258 (48%), Gaps = 33/258 (12%)
Query: 39 FVLLAALIGLYLVAGATVFSALESPGEAEARARWGATLRNFSAAHG-VAEPELRAFLRHY 97
F++L L LYLV GA VFS++E P E R R F H ++E +L FL
Sbjct: 25 FLVLGYL--LYLVFGAVVFSSVELPYEDLLRQELRKLKRRFLEEHECLSEQQLEQFLGRV 82
Query: 98 EAALAAGVRADALRP---RWDFPGAFYFVGTVVSTIGFGMTTPATVGGKAFLIAYGLFGC 154
A GV + WDF A +F TV+ST G+G T P + GGKAF I Y + G
Sbjct: 83 LEASNYGVSVLSNASGNWNWDFTSALFFASTVLSTTGYGHTVPLSDGGKAFCIIYSVIGI 142
Query: 155 AGTILFFNLFLERIISLLAFIMRACRERQLRRSGLLPATFRRGSALSEADSLAGWKPSVY 214
T+LF ++RI + R +L R G + ++
Sbjct: 143 PFTLLFLTAVVQRITV------------HVTRRPVLYFHIRWGFSKQVV--------AIV 182
Query: 215 HVLLILGLFAVLLSC---CASAMYTSVEG-WDYVDSLYFCFVTFSTIGFGDLVSSQHAAY 270
H +L L V +SC +A+++ +E W++++S YFCF++ STIG GD V +
Sbjct: 183 HAVL---LGFVTVSCFFFIPAAVFSVLEDDWNFLESFYFCFISLSTIGLGDYVPGEGYNQ 239
Query: 271 RNQGLYRLGNFLFILLGV 288
+ + LY++G ++LLG+
Sbjct: 240 KFRELYKIGITCYLLLGL 257
>gi|205360983 potassium channel, subfamily K, member 16 isoform 3
[Homo sapiens]
Length = 294
Score = 105 bits (262), Expect = 8e-23
Identities = 84/298 (28%), Positives = 135/298 (45%), Gaps = 35/298 (11%)
Query: 20 PSCCCCCCRRSHLNEDTGRFVLLAALIGLYLVAGATVFSALESPGEAEARARWGATLRNF 79
PS C C GR + L YL+ GAT+F LE EA++R ++ F
Sbjct: 2 PSAGLCSCWG-------GRVLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRF 54
Query: 80 SAAHGVAEP-ELRAFLRHYEAALAAGV--RADALRP-RWDFPGAFYFVGTVVSTIGFGMT 135
+ + + F++ A GV + ++ P WDF +F+F GTVV+TIG+G
Sbjct: 55 LENYTCLDQWAMEQFVQVIMEAWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNL 114
Query: 136 TPATVGGKAFLIAYGLFGCAGTILFFNLFLERIISLLAFIMRACRERQLRRSGLLPATFR 195
P+T G+ F + Y L G ++F N + + LA I R E + RRS +L
Sbjct: 115 APSTEAGQVFCVFYALLGIPLNVIFLNHLGTGLRAHLAAIER--WEDRPRRSQVL----- 167
Query: 196 RGSALSEADSLAGWKPSVYHVLLILGLFAVLLSCCASAMYTSVEGWDYVDSLYFCFVTFS 255
V + L L L +++ +++ VEGW + + YF F+T S
Sbjct: 168 ----------------QVLGLALFLTLGTLVILIFPPMVFSHVEGWSFSEGFYFAFITLS 211
Query: 256 TIGFGDLVSSQHAAYRNQGLYRLGNFLFILLGVCCIYSLFNVISILIKQVLN-WMLRK 312
TIGFGD V + +YR ++ILLG+ + + + +L+ + W+L +
Sbjct: 212 TIGFGDYVVGTDPSKHYISVYRSLAAIWILLGLAWLALILPLGPLLLHRCCQLWLLSR 269
>gi|11641275 potassium family, subfamily K, member 15 [Homo sapiens]
Length = 330
Score = 105 bits (262), Expect = 8e-23
Identities = 95/306 (31%), Positives = 138/306 (45%), Gaps = 52/306 (16%)
Query: 49 YLVAGATVFSALESPGEAEARA----RWGATLRNFSAAHGVAEPELRAFLRHYEAALAAG 104
YL+ GA VF ALES E+ + + GA R F G + + R R LA
Sbjct: 18 YLLVGAAVFDALESEAESGRQRLLVQKRGALRRKF----GFSAEDYRELER-----LALQ 68
Query: 105 VRADALRPRWDFPGAFYFVGTVVSTIGFGMTTPATVGGKAFLIAYGLFGCAGTILFFNLF 164
+W FPG+FYF TV++TIG+G P T GK F + Y L G T++ F
Sbjct: 69 AEPHRAGRQWKFPGSFYFAITVITTIGYGHAAPGTDSGKVFCMFYALLGIPLTLVTFQSL 128
Query: 165 LERIISLLAFIMRACRERQLRRSGLLPATFRRGSALSEADSLAGWKPSVYHVLLILGLFA 224
ER+ +++ R LL A G W L++ GL A
Sbjct: 129 GERLNAVV-------------RRLLLAAKCCLGLR---------WTCVSTENLVVAGLLA 166
Query: 225 VLLSCCASAM-YTSVEGWDYVDSLYFCFVTFSTIGFGDLVSSQHA-AYRNQGLYRLGNFL 282
+ A+ ++ EGW + + Y+CF+T +TIGFGD V+ Q A + + Y +FL
Sbjct: 167 CAATLALGAVAFSHFEGWTFFHAYYYCFITLTTIGFGDFVALQSGEALQRKLPYVAFSFL 226
Query: 283 FILLGVCCIYSLFNVISILIKQVLNWMLRKLSCRCCARCCPA---PGAP------LARRN 333
+ILLG+ I + N++ VL +++ A P+ PGAP L RR
Sbjct: 227 YILLGLTVIGAFLNLV------VLRFLVASADWPERAARPPSPRPPGAPESRGLWLPRRP 280
Query: 334 AITPGS 339
A + GS
Sbjct: 281 ARSVGS 286
>gi|20143946 potassium channel, subfamily K, member 10 isoform 3
[Homo sapiens]
Length = 543
Score = 104 bits (259), Expect = 2e-22
Identities = 71/264 (26%), Positives = 120/264 (45%), Gaps = 23/264 (8%)
Query: 40 VLLAALIGLYLVAGATVFSALESPGEAEARARWGATLRNFSAAHGVAEP-ELRAFLRHYE 98
V + ++ +YLV G VF ALE P E+ + F H P EL ++H
Sbjct: 78 VAIFVVVVVYLVTGGLVFRALEQPFESSQKNTIALEKAEFLRDHVCVSPQELETLIQHAL 137
Query: 99 AALAAGV----RADALRPRWDFPGAFYFVGTVVSTIGFGMTTPATVGGKAFLIAYGLFGC 154
A AGV + WD AF+F GTV++TIG+G P+T GGK F I Y +FG
Sbjct: 138 DADNAGVSPIGNSSNNSSHWDLGSAFFFAGTVITTIGYGNIAPSTEGGKIFCILYAIFG- 196
Query: 155 AGTILFFNLFLERIISLLAFIMRACRERQLRRSGLLPATFRRGSALSEADSLAGWKPSVY 214
I L F++ + + + + R + ++ K V
Sbjct: 197 --------------IPLFGFLLAGIGD---QLGTIFGKSIARVEKVFRKKQVSQTKIRVI 239
Query: 215 HVLLILGLFAVLLSCCASAMYTSVEGWDYVDSLYFCFVTFSTIGFGDLVSSQHAAYRNQG 274
+L + ++ + ++ +EGW ++S+YF VT +T+GFGD V+ +A +
Sbjct: 240 STILFILAGCIVFVTIPAVIFKYIEGWTALESIYFVVVTLTTVGFGDFVAGGNAGINYRE 299
Query: 275 LYRLGNFLFILLGVCCIYSLFNVI 298
Y+ + +IL+G+ ++ ++I
Sbjct: 300 WYKPLVWFWILVGLAYFAAVLSMI 323
>gi|20143944 potassium channel, subfamily K, member 10 isoform 2
[Homo sapiens]
Length = 543
Score = 104 bits (259), Expect = 2e-22
Identities = 71/264 (26%), Positives = 120/264 (45%), Gaps = 23/264 (8%)
Query: 40 VLLAALIGLYLVAGATVFSALESPGEAEARARWGATLRNFSAAHGVAEP-ELRAFLRHYE 98
V + ++ +YLV G VF ALE P E+ + F H P EL ++H
Sbjct: 78 VAIFVVVVVYLVTGGLVFRALEQPFESSQKNTIALEKAEFLRDHVCVSPQELETLIQHAL 137
Query: 99 AALAAGV----RADALRPRWDFPGAFYFVGTVVSTIGFGMTTPATVGGKAFLIAYGLFGC 154
A AGV + WD AF+F GTV++TIG+G P+T GGK F I Y +FG
Sbjct: 138 DADNAGVSPIGNSSNNSSHWDLGSAFFFAGTVITTIGYGNIAPSTEGGKIFCILYAIFG- 196
Query: 155 AGTILFFNLFLERIISLLAFIMRACRERQLRRSGLLPATFRRGSALSEADSLAGWKPSVY 214
I L F++ + + + + R + ++ K V
Sbjct: 197 --------------IPLFGFLLAGIGD---QLGTIFGKSIARVEKVFRKKQVSQTKIRVI 239
Query: 215 HVLLILGLFAVLLSCCASAMYTSVEGWDYVDSLYFCFVTFSTIGFGDLVSSQHAAYRNQG 274
+L + ++ + ++ +EGW ++S+YF VT +T+GFGD V+ +A +
Sbjct: 240 STILFILAGCIVFVTIPAVIFKYIEGWTALESIYFVVVTLTTVGFGDFVAGGNAGINYRE 299
Query: 275 LYRLGNFLFILLGVCCIYSLFNVI 298
Y+ + +IL+G+ ++ ++I
Sbjct: 300 WYKPLVWFWILVGLAYFAAVLSMI 323
>gi|10863961 potassium channel, subfamily K, member 10 isoform 1
[Homo sapiens]
Length = 538
Score = 104 bits (259), Expect = 2e-22
Identities = 71/264 (26%), Positives = 120/264 (45%), Gaps = 23/264 (8%)
Query: 40 VLLAALIGLYLVAGATVFSALESPGEAEARARWGATLRNFSAAHGVAEP-ELRAFLRHYE 98
V + ++ +YLV G VF ALE P E+ + F H P EL ++H
Sbjct: 73 VAIFVVVVVYLVTGGLVFRALEQPFESSQKNTIALEKAEFLRDHVCVSPQELETLIQHAL 132
Query: 99 AALAAGV----RADALRPRWDFPGAFYFVGTVVSTIGFGMTTPATVGGKAFLIAYGLFGC 154
A AGV + WD AF+F GTV++TIG+G P+T GGK F I Y +FG
Sbjct: 133 DADNAGVSPIGNSSNNSSHWDLGSAFFFAGTVITTIGYGNIAPSTEGGKIFCILYAIFG- 191
Query: 155 AGTILFFNLFLERIISLLAFIMRACRERQLRRSGLLPATFRRGSALSEADSLAGWKPSVY 214
I L F++ + + + + R + ++ K V
Sbjct: 192 --------------IPLFGFLLAGIGD---QLGTIFGKSIARVEKVFRKKQVSQTKIRVI 234
Query: 215 HVLLILGLFAVLLSCCASAMYTSVEGWDYVDSLYFCFVTFSTIGFGDLVSSQHAAYRNQG 274
+L + ++ + ++ +EGW ++S+YF VT +T+GFGD V+ +A +
Sbjct: 235 STILFILAGCIVFVTIPAVIFKYIEGWTALESIYFVVVTLTTVGFGDFVAGGNAGINYRE 294
Query: 275 LYRLGNFLFILLGVCCIYSLFNVI 298
Y+ + +IL+G+ ++ ++I
Sbjct: 295 WYKPLVWFWILVGLAYFAAVLSMI 318
>gi|7706135 potassium channel, subfamily K, member 9 [Homo sapiens]
Length = 374
Score = 102 bits (255), Expect = 5e-22
Identities = 69/254 (27%), Positives = 121/254 (47%), Gaps = 33/254 (12%)
Query: 49 YLVAGATVFSALESPGEAEARARWGATLRNFSAAHGVAEPELRAF--LRHYEAALAAGVR 106
YL+ GA VF ALES E + A + ++ + R + AGV+
Sbjct: 18 YLLVGAAVFDALESDHEMREEEKLKAEEIRIKGKYNISSEDYRQLELVILQSEPHRAGVQ 77
Query: 107 ADALRPRWDFPGAFYFVGTVVSTIGFGMTTPATVGGKAFLIAYGLFGCAGTILFFNLFLE 166
W F G+FYF TV++TIG+G P T GKAF + Y + G T++ F E
Sbjct: 78 -------WKFAGSFYFAITVITTIGYGHAAPGTDAGKAFCMFYAVLGIPLTLVMFQSLGE 130
Query: 167 RIISLLAFIMRACRERQLRRSGLLPATFRRGSALSEADSLAGWKPSVYHVLLILGLFAVL 226
R+ + + ++++ ++ R + +S + ++ +G F+ +
Sbjct: 131 RMNTFVRYLLKRIKK----------CCGMRNTDVSMEN------------MVTVGFFSCM 168
Query: 227 -LSCCASAMYTSVEGWDYVDSLYFCFVTFSTIGFGDLVSSQ-HAAYRNQGLYRLGNFLFI 284
C +A ++ E W + + Y+CF+T +TIGFGD V+ Q A + + LY +F++I
Sbjct: 169 GTLCIGAAAFSQCEEWSFFHAYYYCFITLTTIGFGDYVALQTKGALQKKPLYVAFSFMYI 228
Query: 285 LLGVCCIYSLFNVI 298
L+G+ I + N++
Sbjct: 229 LVGLTVIGAFLNLV 242
Score = 32.0 bits (71), Expect = 1.1
Identities = 18/98 (18%), Positives = 38/98 (38%), Gaps = 12/98 (12%)
Query: 241 WDYVDSLYFCFVTFSTIGFGDLVSSQHAAYRNQGLYRLGNFLFILLGVCCIYSLFNVISI 300
W + S YF +TIG+G A + + +LG+ +F +
Sbjct: 78 WKFAGSFYFAITVITTIGYGHAAPGTDAG-------KAFCMFYAVLGIPLTLVMFQSLGE 130
Query: 301 LIKQVLNWMLRKLSCRCCARCCPAPGAPLARRNAITPG 338
+ + ++L+++ +CC ++ N +T G
Sbjct: 131 RMNTFVRYLLKRIK-----KCCGMRNTDVSMENMVTVG 163
Score = 29.6 bits (65), Expect = 5.5
Identities = 23/79 (29%), Positives = 34/79 (43%), Gaps = 8/79 (10%)
Query: 101 LAAGVRADALRPRWDFPGAFYFVGTVVSTIGFG----MTTPATVGGK----AFLIAYGLF 152
L G A + W F A+Y+ ++TIGFG + T + K AF Y L
Sbjct: 171 LCIGAAAFSQCEEWSFFHAYYYCFITLTTIGFGDYVALQTKGALQKKPLYVAFSFMYILV 230
Query: 153 GCAGTILFFNLFLERIISL 171
G F NL + R +++
Sbjct: 231 GLTVIGAFLNLVVLRFLTM 249
>gi|15718767 TRAAK [Homo sapiens]
Length = 393
Score = 100 bits (248), Expect = 3e-21
Identities = 79/275 (28%), Positives = 124/275 (45%), Gaps = 34/275 (12%)
Query: 42 LAALIGLYLVAGATVFSALESPGEAEARARWGATLRNFSAAHG-VAEPELRAFLRHYEAA 100
L AL+ LYLV+GA VF ALE P E +A+ G F AH V++ EL ++ A
Sbjct: 9 LLALVLLYLVSGALVFRALEQPHEQQAQRELGEVREKFLRAHPCVSDQELGLLIKEVADA 68
Query: 101 LAAGV------RADALRPRWDFPGAFYFVGTVVSTIGFGMTTPATVGGKAFLIAYGLFGC 154
L G +++ WD AF+F GT+++TIG+G T G+ F I Y L G
Sbjct: 69 LGGGADPETNSTSNSSHSAWDLGSAFFFSGTIITTIGYGNVALRTDAGRLFCIFYALVG- 127
Query: 155 AGTILFFNLFLERIISLLAFIMRACRERQLRRSGLLPATFRRGSALSEADSLAGWKP--- 211
I L ++ +R L ++ R G EA L P
Sbjct: 128 --------------IPLFGILLAGVGDR-------LGSSLRHGIGHIEAIFLKWHVPPEL 166
Query: 212 -SVYHVLLILGLFAVLLSCCASAMYTSVEGWDYVDSLYFCFVTFSTIGFGDLVSSQHAAY 270
V +L L + +L + ++ +E W ++++YF VT +T+GFGD V+
Sbjct: 167 VRVLSAMLFLLIGCLLFVLTPTFVFCYMEDWSKLEAIYFVIVTLTTVGFGDYVAGADPR- 225
Query: 271 RNQGLYRLGNFLFILLGVCCIYSLFNVISILIKQV 305
++ Y+ + +ILLG+ S+ I ++ V
Sbjct: 226 QDSPAYQPLVWFWILLGLAYFASVLTTIGNWLRVV 260
>gi|205360973 potassium channel, subfamily K, member 16 isoform 4
[Homo sapiens]
Length = 262
Score = 98.6 bits (244), Expect = 1e-20
Identities = 75/248 (30%), Positives = 113/248 (45%), Gaps = 34/248 (13%)
Query: 20 PSCCCCCCRRSHLNEDTGRFVLLAALIGLYLVAGATVFSALESPGEAEARARWGATLRNF 79
PS C C GR + L YL+ GAT+F LE EA++R ++ F
Sbjct: 2 PSAGLCSCWG-------GRVLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRF 54
Query: 80 SAAHGVAEP-ELRAFLRHYEAALAAGV--RADALRP-RWDFPGAFYFVGTVVSTIGFGMT 135
+ + + F++ A GV + ++ P WDF +F+F GTVV+TIG+G
Sbjct: 55 LENYTCLDQWAMEQFVQVIMEAWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNL 114
Query: 136 TPATVGGKAFLIAYGLFGCAGTILFFNLFLERIISLLAFIMRACRERQLRRSGLLPATFR 195
P+T G+ F + Y L G ++F N + + LA I R E + RRS +L
Sbjct: 115 APSTEAGQVFCVFYALLGIPLNVIFLNHLGTGLRAHLAAIER--WEDRPRRSQVL----- 167
Query: 196 RGSALSEADSLAGWKPSVYHVLLILGLFAVLLSCCASAMYTSVEGWDYVDSLYFCFVTFS 255
V + L L L +++ +++ VEGW + + YF F+T S
Sbjct: 168 ----------------QVLGLALFLTLGTLVILIFPPMVFSHVEGWSFSEGFYFAFITLS 211
Query: 256 TIGFGDLV 263
TIGFGD V
Sbjct: 212 TIGFGDYV 219
Score = 30.0 bits (66), Expect = 4.2
Identities = 12/33 (36%), Positives = 18/33 (54%)
Query: 236 TSVEGWDYVDSLYFCFVTFSTIGFGDLVSSQHA 268
T+ WD+ S +F +TIG+G+L S A
Sbjct: 88 TNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEA 120
>gi|205360971 potassium channel, subfamily K, member 16 isoform 1
[Homo sapiens]
Length = 322
Score = 98.6 bits (244), Expect = 1e-20
Identities = 75/248 (30%), Positives = 113/248 (45%), Gaps = 34/248 (13%)
Query: 20 PSCCCCCCRRSHLNEDTGRFVLLAALIGLYLVAGATVFSALESPGEAEARARWGATLRNF 79
PS C C GR + L YL+ GAT+F LE EA++R ++ F
Sbjct: 2 PSAGLCSCWG-------GRVLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRF 54
Query: 80 SAAHGVAEP-ELRAFLRHYEAALAAGV--RADALRP-RWDFPGAFYFVGTVVSTIGFGMT 135
+ + + F++ A GV + ++ P WDF +F+F GTVV+TIG+G
Sbjct: 55 LENYTCLDQWAMEQFVQVIMEAWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNL 114
Query: 136 TPATVGGKAFLIAYGLFGCAGTILFFNLFLERIISLLAFIMRACRERQLRRSGLLPATFR 195
P+T G+ F + Y L G ++F N + + LA I R E + RRS +L
Sbjct: 115 APSTEAGQVFCVFYALLGIPLNVIFLNHLGTGLRAHLAAIER--WEDRPRRSQVL----- 167
Query: 196 RGSALSEADSLAGWKPSVYHVLLILGLFAVLLSCCASAMYTSVEGWDYVDSLYFCFVTFS 255
V + L L L +++ +++ VEGW + + YF F+T S
Sbjct: 168 ----------------QVLGLALFLTLGTLVILIFPPMVFSHVEGWSFSEGFYFAFITLS 211
Query: 256 TIGFGDLV 263
TIGFGD V
Sbjct: 212 TIGFGDYV 219
Score = 30.0 bits (66), Expect = 4.2
Identities = 12/33 (36%), Positives = 18/33 (54%)
Query: 236 TSVEGWDYVDSLYFCFVTFSTIGFGDLVSSQHA 268
T+ WD+ S +F +TIG+G+L S A
Sbjct: 88 TNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEA 120
>gi|4504851 potassium channel, subfamily K, member 5 [Homo sapiens]
Length = 499
Score = 92.4 bits (228), Expect = 7e-19
Identities = 80/262 (30%), Positives = 119/262 (45%), Gaps = 34/262 (12%)
Query: 41 LLAALIGLYLVAGATVFSALESPGEAEARARWGAT----LRNFSAAHGVAEPELRAFLRH 96
LL + I YL GA +F LE P EA+ + L+ F + + L L
Sbjct: 7 LLTSAIIFYLAIGAAIFEVLEEPHWKEAKKNYYTQKLHLLKEFPC---LGQEGLDKILEV 63
Query: 97 YEAALAAGVRADALRP--RWDFPGAFYFVGTVVSTIGFGMTTPATVGGKAFLIAYGLFGC 154
A GV + W++P A F TV++TIG+G P T G+ F + YGLFG
Sbjct: 64 VSDAAGQGVAITGNQTFNNWNWPNAMIFAATVITTIGYGNVAPKTPAGRLFCVFYGLFGV 123
Query: 155 AGTILFFNLFLERIISLLAFI-MRACRERQLRRSGLLPATFRRGSALSEADSLAGWKPSV 213
L L I +L F RA R Q +RG +L +A + +
Sbjct: 124 P-------LCLTWISALGKFFGGRAKRLGQF--------LTKRGVSLRKA------QITC 162
Query: 214 YHVLLILGLFAVLLSCCASAMYTSVEGWDYVDSLYFCFVTFSTIGFGDLVSSQHAAYRNQ 273
+ ++ G+ L+ ++ EGW+Y++ LY+ F+T STIGFGD V+ + +
Sbjct: 163 TVIFIVWGVLVHLV--IPPFVFMVTEGWNYIEGLYYSFITISTIGFGDFVAGVNPSANYH 220
Query: 274 GLYRLGNFLFILLGVCCIYSLF 295
LYR L+I LG+ + SLF
Sbjct: 221 ALYRYFVELWIYLGLAWL-SLF 241
>gi|17025230 potassium channel, subfamily K, member 17 isoform 1
[Homo sapiens]
Length = 332
Score = 83.2 bits (204), Expect = 4e-16
Identities = 76/288 (26%), Positives = 121/288 (42%), Gaps = 42/288 (14%)
Query: 40 VLLAALIGLYLVAGATVFSALESPGEAEA-----RARWGATLRNFSAAHGVAEPELRAFL 94
VLL YL G VF LE ++ R +W L+NF+ + P L + +
Sbjct: 23 VLLLLAYLAYLALGTGVFWTLEGRAAQDSSRSFQRDKW-ELLQNFTC---LDRPALDSLI 78
Query: 95 RHYEAALAAGVRA---DALRPRWDFPGAFYFVGTVVSTIGFGMTTPATVGGKAFLIAYGL 151
R A G RW+ G+F+F + ++TIG+G +P T+ + F I + L
Sbjct: 79 RDVVQAYKNGASLLSNTTSMGRWELVGSFFFSVSTITTIGYGNLSPNTMAARLFCIFFAL 138
Query: 152 FGCAGTILFFNLFLERIISLLAFIMRACRERQLRRSGLLPATFRRGSALSEADSLAGWKP 211
G ++ N R L + G+ R G + D A W
Sbjct: 139 VGIPLNLVVLN-----------------RLGHLMQQGVNHWASRLGGTWQDPDK-ARWLA 180
Query: 212 SVYHVLLILGLFAVLLSCCASAMYTSVEGWDYVDSLYFCFVTFSTIGFGDLVSSQHAAYR 271
+L L LF +L +++ +EGW Y + YF F+T ST+GFGD V + + R
Sbjct: 181 GSGALLSGLLLFLLL----PPLLFSHMEGWSYTEGFYFAFITLSTVGFGDYVIGMNPSQR 236
Query: 272 NQGLYRLGNFLFILLGVCCIYSLFNVISILIKQVLNWM-LRKLSCRCC 318
Y+ L+IL G+ ++++IK +L+ + C CC
Sbjct: 237 YPLWYKNMVSLWILFGMAW-------LALIIKLILSQLETPGRVCSCC 277
>gi|205361107 potassium channel, subfamily K, member 17 isoform 2
[Homo sapiens]
Length = 271
Score = 75.9 bits (185), Expect = 7e-14
Identities = 64/232 (27%), Positives = 97/232 (41%), Gaps = 34/232 (14%)
Query: 40 VLLAALIGLYLVAGATVFSALESPGEAEA-----RARWGATLRNFSAAHGVAEPELRAFL 94
VLL YL G VF LE ++ R +W L+NF+ + P L + +
Sbjct: 23 VLLLLAYLAYLALGTGVFWTLEGRAAQDSSRSFQRDKW-ELLQNFTC---LDRPALDSLI 78
Query: 95 RHYEAALAAGVRA---DALRPRWDFPGAFYFVGTVVSTIGFGMTTPATVGGKAFLIAYGL 151
R A G RW+ G+F+F + ++TIG+G +P T+ + F I + L
Sbjct: 79 RDVVQAYKNGASLLSNTTSMGRWELVGSFFFSVSTITTIGYGNLSPNTMAARLFCIFFAL 138
Query: 152 FGCAGTILFFNLFLERIISLLAFIMRACRERQLRRSGLLPATFRRGSALSEADSLAGWKP 211
G ++ N R L + G+ R G + D A W
Sbjct: 139 VGIPLNLVVLN-----------------RLGHLMQQGVNHWASRLGGTWQDPDK-ARWLA 180
Query: 212 SVYHVLLILGLFAVLLSCCASAMYTSVEGWDYVDSLYFCFVTFSTIGFGDLV 263
+L L LF +L +++ +EGW Y + YF F+T ST+GFGD V
Sbjct: 181 GSGALLSGLLLFLLL----PPLLFSHMEGWSYTEGFYFAFITLSTVGFGDYV 228
Score = 35.8 bits (81), Expect = 0.077
Identities = 25/77 (32%), Positives = 39/77 (50%), Gaps = 8/77 (10%)
Query: 236 TSVEGWDYVDSLYFCFVTFSTIGFGDLVSSQHAAYRNQGLYRLGNFLFILLGVCCIYSLF 295
TS+ W+ V S +F T +TIG+G+L + AA RL F L+G+ +
Sbjct: 96 TSMGRWELVGSFFFSVSTITTIGYGNLSPNTMAA-------RLFCIFFALVGIPLNLVVL 148
Query: 296 NVISILIKQVLN-WMLR 311
N + L++Q +N W R
Sbjct: 149 NRLGHLMQQGVNHWASR 165
>gi|16118231 potassium channel, subfamily K, member 7 isoform A
[Homo sapiens]
Length = 307
Score = 70.9 bits (172), Expect = 2e-12
Identities = 72/265 (27%), Positives = 104/265 (39%), Gaps = 41/265 (15%)
Query: 38 RFVLLAALIGLYLVAGATVFSALESPGEAEARARWGATLRNFSAAHGVAEPE--LRAFLR 95
R+ LL L L GA VF ALE P +A A L F A H P L L
Sbjct: 9 RYGLLVVAHLLALGLGAVVFQALEGPPACRLQAELRAELAAFQAEHRACLPPGALEELLG 68
Query: 96 HYEAALAAGVRA---DALRPRWDFPGAFYFVGTVVSTIGFGMTTPATVGGKAFLIAYGLF 152
A A GV + WD P A F ++++T G+G P + GGKAF + Y
Sbjct: 69 TALATQAHGVSTLGNSSEGRTWDLPSALLFAASILTTTGYGHMAPLSPGGKAFCMVYAAL 128
Query: 153 GCAGTILFFNLFLERIISLLAFIMRACRERQLRRSGLLPATFRRGSALSEADSLAGWKPS 212
G ++ L +R C LLP R A W+ S
Sbjct: 129 GLPASL------------ALVATLRHC---------LLPVLSR-----PRAWVAVHWQLS 162
Query: 213 VYHVLLILGLFAVLLSCCASAMYTSVEGW------DYVDSLYFCFVTFSTIGFGDLVSSQ 266
L+ + LL + + ++ W + ++YFCF + STIG DL+ +
Sbjct: 163 PARAALLQAVALGLLVASSFVLLPALVLWGLQGDCSLLGAVYFCFSSLSTIGLEDLLPGR 222
Query: 267 HAAYRNQGLYRLGNFL---FILLGV 288
+ + +Y LG ++LLG+
Sbjct: 223 GRSL-HPVIYHLGQLALLGYLLLGL 246
>gi|5031821 potassium channel, subfamily K, member 7 isoform C [Homo
sapiens]
Length = 257
Score = 69.3 bits (168), Expect = 6e-12
Identities = 69/258 (26%), Positives = 99/258 (38%), Gaps = 38/258 (14%)
Query: 38 RFVLLAALIGLYLVAGATVFSALESPGEAEARARWGATLRNFSAAHGVAEPE--LRAFLR 95
R+ LL L L GA VF ALE P +A A L F A H P L L
Sbjct: 9 RYGLLVVAHLLALGLGAVVFQALEGPPACRLQAELRAELAAFQAEHRACLPPGALEELLG 68
Query: 96 HYEAALAAGVRA---DALRPRWDFPGAFYFVGTVVSTIGFGMTTPATVGGKAFLIAYGLF 152
A A GV + WD P A F ++++T G+G P + GGKAF + Y
Sbjct: 69 TALATQAHGVSTLGNSSEGRTWDLPSALLFAASILTTTGYGHMAPLSPGGKAFCMVYAAL 128
Query: 153 GCAGTILFFNLFLERIISLLAFIMRACRERQLRRSGLLPATFRRGSALSEADSLAGWKPS 212
G ++ L +R C LLP R A W+ S
Sbjct: 129 GLPASL------------ALVATLRHC---------LLPVLSR-----PRAWVAVHWQLS 162
Query: 213 VYHVLLILGLFAVLLSCCASAMYTSVEGW------DYVDSLYFCFVTFSTIGFGDLVSSQ 266
L+ + LL + + ++ W + ++YFCF + STIG DL+ +
Sbjct: 163 PARAALLQAVALGLLVASSFVLLPALVLWGLQGDCSLLGAVYFCFSSLSTIGLEDLLPGR 222
Query: 267 HAAYRNQGLYRLGNFLFI 284
+ + +Y LG +
Sbjct: 223 GRSL-HPVIYHLGQLALL 239
>gi|16118235 potassium channel, subfamily K, member 7 isoform B
[Homo sapiens]
Length = 252
Score = 69.3 bits (168), Expect = 6e-12
Identities = 69/258 (26%), Positives = 99/258 (38%), Gaps = 38/258 (14%)
Query: 38 RFVLLAALIGLYLVAGATVFSALESPGEAEARARWGATLRNFSAAHGVAEPE--LRAFLR 95
R+ LL L L GA VF ALE P +A A L F A H P L L
Sbjct: 9 RYGLLVVAHLLALGLGAVVFQALEGPPACRLQAELRAELAAFQAEHRACLPPGALEELLG 68
Query: 96 HYEAALAAGVRA---DALRPRWDFPGAFYFVGTVVSTIGFGMTTPATVGGKAFLIAYGLF 152
A A GV + WD P A F ++++T G+G P + GGKAF + Y
Sbjct: 69 TALATQAHGVSTLGNSSEGRTWDLPSALLFAASILTTTGYGHMAPLSPGGKAFCMVYAAL 128
Query: 153 GCAGTILFFNLFLERIISLLAFIMRACRERQLRRSGLLPATFRRGSALSEADSLAGWKPS 212
G ++ L +R C LLP R A W+ S
Sbjct: 129 GLPASL------------ALVATLRHC---------LLPVLSR-----PRAWVAVHWQLS 162
Query: 213 VYHVLLILGLFAVLLSCCASAMYTSVEGW------DYVDSLYFCFVTFSTIGFGDLVSSQ 266
L+ + LL + + ++ W + ++YFCF + STIG DL+ +
Sbjct: 163 PARAALLQAVALGLLVASSFVLLPALVLWGLQGDCSLLGAVYFCFSSLSTIGLEDLLPGR 222
Query: 267 HAAYRNQGLYRLGNFLFI 284
+ + +Y LG +
Sbjct: 223 GRSL-HPVIYHLGQLALL 239
>gi|16118233 potassium channel, subfamily K, member 7 isoform B
[Homo sapiens]
Length = 252
Score = 69.3 bits (168), Expect = 6e-12
Identities = 69/258 (26%), Positives = 99/258 (38%), Gaps = 38/258 (14%)
Query: 38 RFVLLAALIGLYLVAGATVFSALESPGEAEARARWGATLRNFSAAHGVAEPE--LRAFLR 95
R+ LL L L GA VF ALE P +A A L F A H P L L
Sbjct: 9 RYGLLVVAHLLALGLGAVVFQALEGPPACRLQAELRAELAAFQAEHRACLPPGALEELLG 68
Query: 96 HYEAALAAGVRA---DALRPRWDFPGAFYFVGTVVSTIGFGMTTPATVGGKAFLIAYGLF 152
A A GV + WD P A F ++++T G+G P + GGKAF + Y
Sbjct: 69 TALATQAHGVSTLGNSSEGRTWDLPSALLFAASILTTTGYGHMAPLSPGGKAFCMVYAAL 128
Query: 153 GCAGTILFFNLFLERIISLLAFIMRACRERQLRRSGLLPATFRRGSALSEADSLAGWKPS 212
G ++ L +R C LLP R A W+ S
Sbjct: 129 GLPASL------------ALVATLRHC---------LLPVLSR-----PRAWVAVHWQLS 162
Query: 213 VYHVLLILGLFAVLLSCCASAMYTSVEGW------DYVDSLYFCFVTFSTIGFGDLVSSQ 266
L+ + LL + + ++ W + ++YFCF + STIG DL+ +
Sbjct: 163 PARAALLQAVALGLLVASSFVLLPALVLWGLQGDCSLLGAVYFCFSSLSTIGLEDLLPGR 222
Query: 267 HAAYRNQGLYRLGNFLFI 284
+ + +Y LG +
Sbjct: 223 GRSL-HPVIYHLGQLALL 239
>gi|41349443 potassium channel, subfamily T, member 2 [Homo sapiens]
Length = 1135
Score = 41.2 bits (95), Expect = 0.002
Identities = 20/49 (40%), Positives = 29/49 (59%), Gaps = 2/49 (4%)
Query: 216 VLLILGLFAVLLSCCASAMYTSVEG--WDYVDSLYFCFVTFSTIGFGDL 262
++LI L ++ +C + G + DSLYFC VTFST+GFGD+
Sbjct: 200 LILISTLLCLIFTCICGIQHLERIGKKLNLFDSLYFCIVTFSTVGFGDV 248
Score = 30.0 bits (66), Expect = 4.2
Identities = 13/30 (43%), Positives = 17/30 (56%)
Query: 119 AFYFVGTVVSTIGFGMTTPATVGGKAFLIA 148
+ YF ST+GFG TP T K F++A
Sbjct: 232 SLYFCIVTFSTVGFGDVTPETWSSKLFVVA 261
>gi|32469495 potassium channel, subfamily K, member 18 [Homo
sapiens]
Length = 384
Score = 40.4 bits (93), Expect = 0.003
Identities = 30/111 (27%), Positives = 43/111 (38%), Gaps = 9/111 (8%)
Query: 49 YLVAGATVFSALE------SPGEAEARARWGATLRNFSAAHGVAEPELRAFLRHYEAALA 102
Y + GA VFSA+E + + E R + + V E + H +
Sbjct: 33 YALVGAVVFSAIEDGQVLVAADDGEFEKFLEELCRILNCSETVVEDRKQDLQGHLQKVKP 92
Query: 103 AGVRADALRPRWDFPGAFYFVGTVVSTIGFGMTTPATVGGKAFLIAYGLFG 153
W F + +F TV ST+G+G P T GK + Y LFG
Sbjct: 93 QWFNRTT---HWSFLSSLFFCCTVFSTVGYGYIYPVTRLGKYLCMLYALFG 140
Score = 39.3 bits (90), Expect = 0.007
Identities = 20/47 (42%), Positives = 30/47 (63%), Gaps = 1/47 (2%)
Query: 217 LLILGLFAVLLSCCASAMYTSVEGWDYVDSLYFCFVTFSTIGFGDLV 263
++ L +FA + SC A+ + D+ ++ YFCFVT +TIGFGD V
Sbjct: 285 IIALIVFAYI-SCAAAILPFWETQLDFENAFYFCFVTLTTIGFGDTV 330
Score = 36.6 bits (83), Expect = 0.045
Identities = 18/57 (31%), Positives = 29/57 (50%), Gaps = 16/57 (28%)
Query: 241 WDYVDSLYFCFVTFSTIGFGDLVSSQHAAYRNQGLYRLGNFLFILLGVCCIYSLFNV 297
W ++ SL+FC FST+G+G + + RLG +L C +Y+LF +
Sbjct: 101 WSFLSSLFFCCTVFSTVGYGYIYP----------VTRLGKYL------CMLYALFGI 141
Score = 36.2 bits (82), Expect = 0.059
Identities = 24/74 (32%), Positives = 32/74 (43%), Gaps = 4/74 (5%)
Query: 107 ADALRPRW----DFPGAFYFVGTVVSTIGFGMTTPATVGGKAFLIAYGLFGCAGTILFFN 162
A A+ P W DF AFYF ++TIGFG T F Y + G + F
Sbjct: 297 AAAILPFWETQLDFENAFYFCFVTLTTIGFGDTVLEHPNFFLFFSIYIIVGMEIVFIAFK 356
Query: 163 LFLERIISLLAFIM 176
L R+I + +M
Sbjct: 357 LVQNRLIDIYKNVM 370
>gi|240255505 potassium channel, subfamily T, member 1 [Homo
sapiens]
Length = 1235
Score = 36.2 bits (82), Expect = 0.059
Identities = 19/50 (38%), Positives = 27/50 (54%), Gaps = 6/50 (12%)
Query: 219 ILGLFAVLL------SCCASAMYTSVEGWDYVDSLYFCFVTFSTIGFGDL 262
+L LF LL +C + + E + S YFC VTFST+G+GD+
Sbjct: 271 VLILFCTLLCLVFTGTCGIQHLERAGENLSLLTSFYFCIVTFSTVGYGDV 320
>gi|33620725 calcipressin 1 isoform a [Homo sapiens]
Length = 252
Score = 34.3 bits (77), Expect = 0.22
Identities = 19/39 (48%), Positives = 24/39 (61%)
Query: 51 VAGATVFSALESPGEAEARARWGATLRNFSAAHGVAEPE 89
VAG + +A E+ AEARAR G TLR F+ G AE +
Sbjct: 5 VAGPQLGAAAEAAEAAEARARPGVTLRPFAPLSGAAEAD 43
>gi|27436981 potassium voltage-gated channel, Shal-related
subfamily, member 1 [Homo sapiens]
Length = 647
Score = 31.6 bits (70), Expect = 1.5
Identities = 11/29 (37%), Positives = 19/29 (65%)
Query: 117 PGAFYFVGTVVSTIGFGMTTPATVGGKAF 145
P AF++ ++T+G+G P+T+ GK F
Sbjct: 360 PAAFWYTIVTMTTLGYGDMVPSTIAGKIF 388
Score = 29.3 bits (64), Expect = 7.2
Identities = 18/53 (33%), Positives = 27/53 (50%)
Query: 246 SLYFCFVTFSTIGFGDLVSSQHAAYRNQGLYRLGNFLFILLGVCCIYSLFNVI 298
+ ++ VT +T+G+GD+V S A + L L I L V I S F+ I
Sbjct: 362 AFWYTIVTMTTLGYGDMVPSTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRI 414
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.327 0.139 0.436
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,894,130
Number of Sequences: 37866
Number of extensions: 689025
Number of successful extensions: 3769
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 57
Number of HSP's successfully gapped in prelim test: 23
Number of HSP's that attempted gapping in prelim test: 3514
Number of HSP's gapped (non-prelim): 191
length of query: 430
length of database: 18,247,518
effective HSP length: 105
effective length of query: 325
effective length of database: 14,271,588
effective search space: 4638266100
effective search space used: 4638266100
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.