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Search of human proteins with 224586804
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|224586804 DNA-directed DNA polymerase epsilon 3 [Homo
sapiens]
(147 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|224586804 DNA-directed DNA polymerase epsilon 3 [Homo sapiens] 286 3e-78
gi|5453780 nuclear transcription factor Y, beta [Homo sapiens] 74 3e-14
gi|4503381 down-regulator of transcription 1 [Homo sapiens] 60 7e-10
gi|239744307 PREDICTED: similar to hCG1991922 [Homo sapiens] 55 3e-08
gi|4757900 calreticulin precursor [Homo sapiens] 54 4e-08
gi|239745093 PREDICTED: hypothetical protein XP_002343359 [Homo ... 51 3e-07
gi|239749996 PREDICTED: similar to hCG1991922 [Homo sapiens] 50 5e-07
gi|17975763 myelin transcription factor 1 [Homo sapiens] 50 5e-07
gi|4504425 high-mobility group box 1 [Homo sapiens] 50 7e-07
gi|169202818 PREDICTED: similar to hCG1991922 [Homo sapiens] 50 7e-07
gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi... 49 2e-06
gi|60498973 myelin transcription factor 1-like [Homo sapiens] 48 3e-06
gi|21735569 claspin [Homo sapiens] 48 3e-06
gi|194688135 high-mobility group box 2 [Homo sapiens] 47 6e-06
gi|194688133 high-mobility group box 2 [Homo sapiens] 47 6e-06
gi|11321591 high-mobility group box 2 [Homo sapiens] 47 6e-06
gi|169210053 PREDICTED: hypothetical protein [Homo sapiens] 47 7e-06
gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo... 47 7e-06
gi|4506411 Ran GTPase activating protein 1 [Homo sapiens] 46 1e-05
gi|55956788 nucleolin [Homo sapiens] 46 1e-05
gi|115511012 coiled-coil domain containing 136 [Homo sapiens] 46 1e-05
gi|239050813 lipoxygenase homology domains 1 isoform 1 [Homo sap... 45 2e-05
gi|56806673 high-mobility group box 1-like 1 [Homo sapiens] 45 3e-05
gi|22749303 hypothetical protein LOC196477 [Homo sapiens] 45 3e-05
gi|46852388 cell-cycle and apoptosis regulatory protein 1 [Homo ... 44 4e-05
gi|167614488 TBC1 domain family, member 10B [Homo sapiens] 44 4e-05
gi|24497618 ATPase family, AAA domain containing 2 [Homo sapiens] 44 5e-05
gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens] 44 5e-05
gi|83716024 kinesin family member 21B [Homo sapiens] 44 5e-05
gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens] 44 5e-05
>gi|224586804 DNA-directed DNA polymerase epsilon 3 [Homo sapiens]
Length = 147
Score = 286 bits (733), Expect = 3e-78
Identities = 147/147 (100%), Positives = 147/147 (100%)
Query: 1 MAERPEDLNLPNAVITRIIKEALPDGVNISKEARSAISRAASVFVLYATSCANNFAMKGK 60
MAERPEDLNLPNAVITRIIKEALPDGVNISKEARSAISRAASVFVLYATSCANNFAMKGK
Sbjct: 1 MAERPEDLNLPNAVITRIIKEALPDGVNISKEARSAISRAASVFVLYATSCANNFAMKGK 60
Query: 61 RKTLNASDVLSAMEEMEFQRFVTPLKEALEAYRREQKGKKEASEQKKKDKDKKTDSEEQD 120
RKTLNASDVLSAMEEMEFQRFVTPLKEALEAYRREQKGKKEASEQKKKDKDKKTDSEEQD
Sbjct: 61 RKTLNASDVLSAMEEMEFQRFVTPLKEALEAYRREQKGKKEASEQKKKDKDKKTDSEEQD 120
Query: 121 KSRDEDNDEDEERLEEEEQNEEEEVDN 147
KSRDEDNDEDEERLEEEEQNEEEEVDN
Sbjct: 121 KSRDEDNDEDEERLEEEEQNEEEEVDN 147
>gi|5453780 nuclear transcription factor Y, beta [Homo sapiens]
Length = 207
Score = 74.3 bits (181), Expect = 3e-14
Identities = 37/97 (38%), Positives = 57/97 (58%)
Query: 4 RPEDLNLPNAVITRIIKEALPDGVNISKEARSAISRAASVFVLYATSCANNFAMKGKRKT 63
R +D+ LP A + RI+K A+P I+K+A+ + S F+ + TS A+ + KRKT
Sbjct: 53 REQDIYLPIANVARIMKNAIPQTGKIAKDAKECVQECVSEFISFITSEASERCHQEKRKT 112
Query: 64 LNASDVLSAMEEMEFQRFVTPLKEALEAYRREQKGKK 100
+N D+L AM + F +V PLK L+ +R KG+K
Sbjct: 113 INGEDILFAMSTLGFDSYVEPLKLYLQKFREAMKGEK 149
>gi|4503381 down-regulator of transcription 1 [Homo sapiens]
Length = 176
Score = 60.1 bits (144), Expect = 7e-10
Identities = 29/100 (29%), Positives = 58/100 (58%), Gaps = 1/100 (1%)
Query: 6 EDLNLPNAVITRIIKEALPDGVNISKEARSAISRAASVFVLYATSCANNFAMKGKRKTLN 65
+DL +P A I ++IKE LP+ V ++ +AR + + F+ +S AN K ++KT++
Sbjct: 9 DDLTIPRAAINKMIKETLPN-VRVANDARELVVNCCTEFIHLISSEANEICNKSEKKTIS 67
Query: 66 ASDVLSAMEEMEFQRFVTPLKEALEAYRREQKGKKEASEQ 105
V+ A+E + F +++ +KE L+ + +++AS +
Sbjct: 68 PEHVIQALESLGFGSYISEVKEVLQECKTVALKRRKASSR 107
>gi|239744307 PREDICTED: similar to hCG1991922 [Homo sapiens]
Length = 486
Score = 54.7 bits (130), Expect = 3e-08
Identities = 39/130 (30%), Positives = 66/130 (50%), Gaps = 22/130 (16%)
Query: 35 SAISRAASVFVLYATSCANNFAMKGKRKTLNASDVLSAMEEM----------EFQRFVTP 84
+A R S F LY + +KG+R L+ DV + EM +++
Sbjct: 229 NAPKRPPSAFFLYFSEYGPK--IKGERPGLSFGDVAKKLGEMWNNTAADDKQPYEKRSAK 286
Query: 85 LKEALE----AYRREQK------GKKEASEQKKKDKDKKTDSEEQDKSRDEDNDEDEERL 134
LKE E AYR + K G +A++ KKK ++++ + +E+D+ ++D DEDEE
Sbjct: 287 LKEKYEKDIAAYRAKGKHDAANNGVVKAAKSKKKKEEEENEEDEEDEEEEKDEDEDEEDD 346
Query: 135 EEEEQNEEEE 144
E+EE ++E+
Sbjct: 347 EDEEDGDDEQ 356
>gi|4757900 calreticulin precursor [Homo sapiens]
Length = 417
Score = 54.3 bits (129), Expect = 4e-08
Identities = 24/69 (34%), Positives = 46/69 (66%)
Query: 77 EFQRFVTPLKEALEAYRREQKGKKEASEQKKKDKDKKTDSEEQDKSRDEDNDEDEERLEE 136
EF + +A E ++++ +++ +++++DK +K + E +DK DED DEDEE E+
Sbjct: 341 EFGNETWGVTKAAEKQMKDKQDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKDEDEEDEED 400
Query: 137 EEQNEEEEV 145
+E++EEE+V
Sbjct: 401 KEEDEEEDV 409
Score = 35.0 bits (79), Expect = 0.023
Identities = 18/61 (29%), Positives = 37/61 (60%), Gaps = 2/61 (3%)
Query: 86 KEALEAYRREQKGKKEASEQKKKDKDKKTDSEE-QDKSRDE-DNDEDEERLEEEEQNEEE 143
K+ + EQ+ K+E ++K+K++++ D E+ +DK DE D ++ EE EE+ + +
Sbjct: 355 KQMKDKQDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKDEDEEDEEDKEEDEEEDVPGQAK 414
Query: 144 E 144
+
Sbjct: 415 D 415
Score = 28.9 bits (63), Expect = 1.6
Identities = 13/51 (25%), Positives = 30/51 (58%), Gaps = 3/51 (5%)
Query: 86 KEALEAYRREQKGKKEASEQKKKDKDKKTDSEEQDKSRDEDNDEDEERLEE 136
+E + R+E++ ++ + + KD+D++ +E+DK DE+ D + +E
Sbjct: 369 EEEEDKKRKEEEEAEDKEDDEDKDEDEE---DEEDKEEDEEEDVPGQAKDE 416
>gi|239745093 PREDICTED: hypothetical protein XP_002343359 [Homo
sapiens]
Length = 142
Score = 51.2 bits (121), Expect = 3e-07
Identities = 24/74 (32%), Positives = 45/74 (60%)
Query: 71 SAMEEMEFQRFVTPLKEALEAYRREQKGKKEASEQKKKDKDKKTDSEEQDKSRDEDNDED 130
S EE R A ++ RRE+K ++E ++K+ ++K+ + + ++K +++ +E+
Sbjct: 45 SVKEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEE 104
Query: 131 EERLEEEEQNEEEE 144
EE EEEE+ EEEE
Sbjct: 105 EEEEEEEEEEEEEE 118
Score = 46.2 bits (108), Expect = 1e-05
Identities = 19/52 (36%), Positives = 35/52 (67%)
Query: 90 EAYRREQKGKKEASEQKKKDKDKKTDSEEQDKSRDEDNDEDEERLEEEEQNE 141
E RRE+K ++E ++K+ + K+ + EE+ + +E+ +E+EE EEEE+ E
Sbjct: 69 EEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEE 120
Score = 37.7 bits (86), Expect = 0.003
Identities = 18/63 (28%), Positives = 39/63 (61%), Gaps = 8/63 (12%)
Query: 90 EAYRREQKGKKEA---SEQKKKDKDKKTDSEEQDKSRDEDNDEDEERLE-----EEEQNE 141
E RRE+K ++E ++++K+++K+ + EE+++ +E+ +E+EE + E + E
Sbjct: 74 EEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERETE 133
Query: 142 EEE 144
EE
Sbjct: 134 TEE 136
Score = 32.3 bits (72), Expect = 0.15
Identities = 13/56 (23%), Positives = 34/56 (60%)
Query: 90 EAYRREQKGKKEASEQKKKDKDKKTDSEEQDKSRDEDNDEDEERLEEEEQNEEEEV 145
E RRE K +++ E+++++++++ + EE+++ +E+ E E + EE+ +
Sbjct: 84 EEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERETETEEKRL 139
Score = 28.5 bits (62), Expect = 2.1
Identities = 17/85 (20%), Positives = 43/85 (50%), Gaps = 3/85 (3%)
Query: 53 NNFAMKGKRKTLNASDVLSAMEEMEFQRFVTPLKEALEAYRREQKGKKEASEQKKKDKDK 112
++ A RK+ + + E +R +E + E+K ++E E++++++++
Sbjct: 55 HSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEE 114
Query: 113 KTDSEEQDKS---RDEDNDEDEERL 134
+ + EE S R+ + + +E+RL
Sbjct: 115 EEEEEEVSFSLATRERETETEEKRL 139
>gi|239749996 PREDICTED: similar to hCG1991922 [Homo sapiens]
Length = 487
Score = 50.4 bits (119), Expect = 5e-07
Identities = 40/131 (30%), Positives = 63/131 (48%), Gaps = 22/131 (16%)
Query: 35 SAISRAASVFVLYATSCANNFAMKGKRKTLNASDVLSAMEEM----------EFQRFVTP 84
+A R S F LY + +KG+R L+ DV + EM +++
Sbjct: 229 NAPKRPPSAFFLYFSEYGPK--IKGERPGLSFGDVAKKLGEMWNNTAADDKQPYEKRSAK 286
Query: 85 LKEALE----AYRREQKGKKEASE----QKKKDKDKKTDSEEQDKSRDEDNDEDEERLEE 136
LKE E AYR KGK +A+ + K K KK + E ++ DE+ ++DEE +E
Sbjct: 287 LKEKYEKDIAAYRA--KGKHDAANNGVVKAAKSKKKKEEEENEEDEEDEEEEKDEEDEDE 344
Query: 137 EEQNEEEEVDN 147
E+ +EE+ D+
Sbjct: 345 EDDEDEEDGDD 355
>gi|17975763 myelin transcription factor 1 [Homo sapiens]
Length = 1121
Score = 50.4 bits (119), Expect = 5e-07
Identities = 25/84 (29%), Positives = 50/84 (59%), Gaps = 4/84 (4%)
Query: 65 NASDVLSAMEEMEFQRFVTPLKEALEAYRREQKG----KKEASEQKKKDKDKKTDSEEQD 120
+A +V+ E L++A +QKG ++E E+++++++++ D EE++
Sbjct: 220 DAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEE 279
Query: 121 KSRDEDNDEDEERLEEEEQNEEEE 144
+ +E+ +E+EE EEEE+ EEEE
Sbjct: 280 EEEEEEEEEEEEEEEEEEEEEEEE 303
Score = 47.8 bits (112), Expect = 3e-06
Identities = 17/49 (34%), Positives = 38/49 (77%)
Query: 95 EQKGKKEASEQKKKDKDKKTDSEEQDKSRDEDNDEDEERLEEEEQNEEE 143
E++ ++E E++++++D++ + EE+++ +E+ +E+EE EEEE+ EEE
Sbjct: 258 EEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEE 306
Score = 44.3 bits (103), Expect = 4e-05
Identities = 15/56 (26%), Positives = 40/56 (71%)
Query: 86 KEALEAYRREQKGKKEASEQKKKDKDKKTDSEEQDKSRDEDNDEDEERLEEEEQNE 141
++ + ++ E + ++E E++++D++++ + EE+++ +E+ +E+EE EEEE+ E
Sbjct: 251 QKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEE 306
Score = 40.0 bits (92), Expect = 7e-04
Identities = 15/60 (25%), Positives = 38/60 (63%)
Query: 86 KEALEAYRREQKGKKEASEQKKKDKDKKTDSEEQDKSRDEDNDEDEERLEEEEQNEEEEV 145
K L +++ ++E E+++ +++++ + EE+++ +E+ +E+EE EEEE+ +V
Sbjct: 252 KGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDV 311
Score = 38.1 bits (87), Expect = 0.003
Identities = 23/74 (31%), Positives = 39/74 (52%), Gaps = 1/74 (1%)
Query: 71 SAMEEMEFQRFVTPLKEALEAYRREQKGKKEASEQKKKDKDKKTDSEEQDKSRDEDNDED 130
+A EE E F+ P ++A E + ++ Q +D + S+++ E+ DE+
Sbjct: 205 AASEEGEKGLFIQP-EDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEEDEE 263
Query: 131 EERLEEEEQNEEEE 144
EE EEEE+ +EEE
Sbjct: 264 EEEEEEEEEEDEEE 277
>gi|4504425 high-mobility group box 1 [Homo sapiens]
Length = 215
Score = 50.1 bits (118), Expect = 7e-07
Identities = 42/129 (32%), Positives = 64/129 (49%), Gaps = 24/129 (18%)
Query: 35 SAISRAASVFVLYATSCANNFAMKGKRKTLNASDVLSAMEEM----------EFQRFVTP 84
+A R S F L+ + +KG+ L+ DV + EM +++
Sbjct: 93 NAPKRPPSAFFLFCSEYRPK--IKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAK 150
Query: 85 LKEALE----AYRREQKGKKEASEQK--KKDKDKKTDSEEQDKSRDEDNDEDEERLEEEE 138
LKE E AYR KGK +A+++ K +K KK EE+D E+++EDEE E+EE
Sbjct: 151 LKEKYEKDIAAYRA--KGKPDAAKKGVVKAEKSKKKKEEEED----EEDEEDEEEEEDEE 204
Query: 139 QNEEEEVDN 147
+EEE D+
Sbjct: 205 DEDEEEDDD 213
>gi|169202818 PREDICTED: similar to hCG1991922 [Homo sapiens]
Length = 488
Score = 50.1 bits (118), Expect = 7e-07
Identities = 37/134 (27%), Positives = 69/134 (51%), Gaps = 28/134 (20%)
Query: 35 SAISRAASVFVLYATSCANNFAMKGKRKTLNASDVLSAMEEM----------EFQRFVTP 84
+A R S F LY + +KG+R L+ DV + EM +++
Sbjct: 229 NAPKRPPSAFFLYFSEYGPK--IKGERPGLSFGDVAKKLGEMWNNTAADDKQPYEKRSAK 286
Query: 85 LKEALE----AYRREQKGKKEA----------SEQKKKDKDKKTDSEEQDKSRDEDNDED 130
LKE E AYR KGK +A S++KK++++ + D E++++ +DE+++++
Sbjct: 287 LKEKYEKDIAAYRA--KGKHDAANNGVVKAAKSKKKKEEEENEEDEEDEEEEKDEEDEDE 344
Query: 131 EERLEEEEQNEEEE 144
E+ +EEE ++E+
Sbjct: 345 EDDEDEEEDGDDEQ 358
>gi|239508778 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 123
Score = 48.9 bits (115), Expect = 2e-06
Identities = 29/94 (30%), Positives = 49/94 (52%), Gaps = 15/94 (15%)
Query: 58 KGKRKTLNASDVLSAMEEMEFQRFVTPLKEALEAYRREQKGKKEASEQKKKDKDKKTDSE 117
K K++T + EE E KE +R++K K++ ++K K+ +K+ + E
Sbjct: 5 KKKKETEETEETEETEEEEE--------KEGKRKEKRKEKRKEKEKKKKTKETEKRKEKE 56
Query: 118 EQDKSRD-------EDNDEDEERLEEEEQNEEEE 144
E++K R E+ + +EE EEEE+ EEEE
Sbjct: 57 EEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEE 90
Score = 47.0 bits (110), Expect = 6e-06
Identities = 23/87 (26%), Positives = 49/87 (56%)
Query: 58 KGKRKTLNASDVLSAMEEMEFQRFVTPLKEALEAYRREQKGKKEASEQKKKDKDKKTDSE 117
K K+K ++ EE E + ++ +R++K KK+ +++ +K K+K+ + +
Sbjct: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60
Query: 118 EQDKSRDEDNDEDEERLEEEEQNEEEE 144
++ + R + +E+E EEEE+ EE+E
Sbjct: 61 KRKRKRKKKKEEEEREEEEEEEEEEKE 87
Score = 42.0 bits (97), Expect = 2e-04
Identities = 16/59 (27%), Positives = 36/59 (61%)
Query: 86 KEALEAYRREQKGKKEASEQKKKDKDKKTDSEEQDKSRDEDNDEDEERLEEEEQNEEEE 144
KE + + +K K++ E+KK+ + +K EE+++ +E+ +E+E+ EE+E+ +
Sbjct: 40 KEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRK 98
Score = 39.3 bits (90), Expect = 0.001
Identities = 29/96 (30%), Positives = 47/96 (48%), Gaps = 16/96 (16%)
Query: 58 KGKRKTLNASDVLSAMEEMEFQRFVTPLKEALEAYRREQKGKKEASE-QKKKDKD----- 111
K K+K + E E + KE + R+E++ KK+ E +K+K+K+
Sbjct: 2 KKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKK 61
Query: 112 ------KKTDSEEQDKSRDEDNDEDEERLEEEEQNE 141
KK + EE R+E+ +E+EE EEEE+ E
Sbjct: 62 RKRKRKKKKEEEE----REEEEEEEEEEKEEEEKEE 93
Score = 37.7 bits (86), Expect = 0.003
Identities = 20/87 (22%), Positives = 47/87 (54%), Gaps = 12/87 (13%)
Query: 58 KGKRKTLNASDVLSAMEEMEFQRFVTPLKEALEAYRREQKGKKEASEQKKKDKDKKTDSE 117
K K+K ++ EE E +R +R++K KKE E+++++++++ + E
Sbjct: 40 KEKKKKTKETEKRKEKEEEEKKR------------KRKRKKKKEEEEREEEEEEEEEEKE 87
Query: 118 EQDKSRDEDNDEDEERLEEEEQNEEEE 144
E++K + ++R +EE+ E+++
Sbjct: 88 EEEKEEGRRRKKKKKRRRKEEEEEKKK 114
Score = 37.4 bits (85), Expect = 0.005
Identities = 18/69 (26%), Positives = 40/69 (57%), Gaps = 11/69 (15%)
Query: 86 KEALEAYRREQKGKKEASEQKKKDKDKKTDSEEQDKSRDEDNDEDEE-----------RL 134
KE + +E++ KK ++KKK ++++ + EE+++ +++ +E EE R
Sbjct: 47 KETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRK 106
Query: 135 EEEEQNEEE 143
EEEE+ +++
Sbjct: 107 EEEEEKKKK 115
Score = 37.0 bits (84), Expect = 0.006
Identities = 18/87 (20%), Positives = 48/87 (55%), Gaps = 4/87 (4%)
Query: 58 KGKRKTLNASDVLSAMEEMEFQRFVTPLKEALEAYRREQKGKKEASEQKKKDKDKKTDSE 117
+GKRK +E E ++ ++ E E+K K++ ++K++++ ++ + E
Sbjct: 26 EGKRKEKRKEK----RKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEE 81
Query: 118 EQDKSRDEDNDEDEERLEEEEQNEEEE 144
E+++ +E+ +E R +++++ +EE
Sbjct: 82 EEEEKEEEEKEEGRRRKKKKKRRRKEE 108
Score = 28.9 bits (63), Expect = 1.6
Identities = 21/60 (35%), Positives = 29/60 (48%), Gaps = 3/60 (5%)
Query: 58 KGKRKTLNASDVLSAMEEMEFQRFVTPLKEALEAYRREQKGK---KEASEQKKKDKDKKT 114
K KRK + EE E + +E E RR++K K KE E+KKK + +KT
Sbjct: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKT 120
Score = 28.5 bits (62), Expect = 2.1
Identities = 13/50 (26%), Positives = 30/50 (60%), Gaps = 8/50 (16%)
Query: 105 QKKKDKDKKTDSEEQDKSRDEDNDED--------EERLEEEEQNEEEEVD 146
+KKK K K+T+ E+ + +E+ +++ E+R E+E++ + +E +
Sbjct: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETE 50
>gi|60498973 myelin transcription factor 1-like [Homo sapiens]
Length = 1184
Score = 48.1 bits (113), Expect = 3e-06
Identities = 30/95 (31%), Positives = 50/95 (52%), Gaps = 6/95 (6%)
Query: 55 FAMKGKRKTLNASDVLSAMEEMEFQRFVTPLKEALEAYRREQKGKKEASEQKKKDKDKKT 114
FA+K +++ D E+M+ + E E + E E ++ D++++
Sbjct: 78 FAVKADSSSVDECDDSDGTEDMDEKEE----DEGEEYSEDNDEPGDEDEEDEEGDREEEE 133
Query: 115 DSEEQDKSRDEDND--EDEERLEEEEQNEEEEVDN 147
+ EE+D+ DED + EDEE EEEE+ EEEE +N
Sbjct: 134 EIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEEN 168
Score = 31.6 bits (70), Expect = 0.25
Identities = 17/52 (32%), Positives = 24/52 (46%)
Query: 93 RREQKGKKEASEQKKKDKDKKTDSEEQDKSRDEDNDEDEERLEEEEQNEEEE 144
R+ Q + + K+K K DS D+ D D ED + EE+E E E
Sbjct: 61 RKTQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEEYSE 112
>gi|21735569 claspin [Homo sapiens]
Length = 1339
Score = 47.8 bits (112), Expect = 3e-06
Identities = 24/69 (34%), Positives = 43/69 (62%), Gaps = 9/69 (13%)
Query: 85 LKEALEAYRREQKGKKEAS---------EQKKKDKDKKTDSEEQDKSRDEDNDEDEERLE 135
L+EA++ R E++ K++A E++++++++ TD E+D + +E EE LE
Sbjct: 601 LQEAMKLRRFEERQKRQALFKLDNEDGFEEEEEEEEEMTDESEEDGEEKVEKEEKEEELE 660
Query: 136 EEEQNEEEE 144
EEE+ EEEE
Sbjct: 661 EEEEKEEEE 669
Score = 40.4 bits (93), Expect = 5e-04
Identities = 22/76 (28%), Positives = 48/76 (63%), Gaps = 9/76 (11%)
Query: 74 EEMEFQRFVTPLK-EAL------EAYRREQKGKKEASEQKKKDKDKKTDSEEQDKSRDED 126
E M+ +RF K +AL + + E++ ++E +++ ++D ++K + EE+++ +E+
Sbjct: 603 EAMKLRRFEERQKRQALFKLDNEDGFEEEEEEEEEMTDESEEDGEEKVEKEEKEEELEEE 662
Query: 127 NDEDEERLEEEEQNEE 142
+++EE EEEE N+E
Sbjct: 663 EEKEEE--EEEEGNQE 676
Score = 31.6 bits (70), Expect = 0.25
Identities = 17/60 (28%), Positives = 35/60 (58%), Gaps = 3/60 (5%)
Query: 87 EALEAYRREQKGKKEASEQKKKDKDKKTDSEEQDKSRDEDNDEDEERLEEEEQNEEEEVD 146
+ L+A +E + E++K+ K D+E+ +E+ +E+EE +E E++ EE+V+
Sbjct: 595 QVLKAKLQEAMKLRRFEERQKRQALFKLDNED---GFEEEEEEEEEMTDESEEDGEEKVE 651
Score = 30.8 bits (68), Expect = 0.42
Identities = 27/95 (28%), Positives = 45/95 (47%), Gaps = 11/95 (11%)
Query: 55 FAMKGKRKTLNASDVLSAMEEMEFQRFVTPLKEALEAYRREQKGKKEASEQKKKDKDKKT 114
F + KR+ L D EE E + + + E E+ K+E E+ +++++K+
Sbjct: 610 FEERQKRQALFKLDNEDGFEEEEEEE--EEMTDESEEDGEEKVEKEEKEEELEEEEEKEE 667
Query: 115 DSEEQDKSRDEDNDEDEERL---EEEEQNEEEEVD 146
+ EE E N E E L EE E +E+E+D
Sbjct: 668 EEEE------EGNQETAEFLLSSEEIETKDEKEMD 696
Score = 30.0 bits (66), Expect = 0.72
Identities = 18/65 (27%), Positives = 33/65 (50%), Gaps = 3/65 (4%)
Query: 84 PLKEALEAYRREQKGKKEASEQKKKDKDKKTDSEEQDKSRDEDNDED---EERLEEEEQN 140
P++EAL KE +++++ D + S + + DED D + LE+ E +
Sbjct: 973 PMEEALALCSGSFPTDKEEEDEEEEFGDFRLVSNDNEFDSDEDEHSDSGNDLALEDHEDD 1032
Query: 141 EEEEV 145
+EEE+
Sbjct: 1033 DEEEL 1037
Score = 27.3 bits (59), Expect = 4.7
Identities = 19/66 (28%), Positives = 33/66 (50%), Gaps = 1/66 (1%)
Query: 82 VTPLKEALEAYRREQKGKK-EASEQKKKDKDKKTDSEEQDKSRDEDNDEDEERLEEEEQN 140
VT + L+ + G+K + + K ++ K EE+ K + ++E+ EEEE+
Sbjct: 575 VTLAPKKLDGASHTKPGEKLQVLKAKLQEAMKLRRFEERQKRQALFKLDNEDGFEEEEEE 634
Query: 141 EEEEVD 146
EEE D
Sbjct: 635 EEEMTD 640
>gi|194688135 high-mobility group box 2 [Homo sapiens]
Length = 209
Score = 47.0 bits (110), Expect = 6e-06
Identities = 29/78 (37%), Positives = 47/78 (60%), Gaps = 9/78 (11%)
Query: 71 SAMEEMEFQRFVTPLKEALE----AYRREQKGKKEASEQKKKDKDKKTDSEEQDKSRDED 126
SA ++ +++ LKE E AYR KGK EA KK + T S+++++ DE+
Sbjct: 137 SAKDKQPYEQKAAKLKEKYEKDIAAYRA--KGKSEAG---KKGPGRPTGSKKKNEPEDEE 191
Query: 127 NDEDEERLEEEEQNEEEE 144
+E+EE +EEE++E+EE
Sbjct: 192 EEEEEEDEDEEEEDEDEE 209
>gi|194688133 high-mobility group box 2 [Homo sapiens]
Length = 209
Score = 47.0 bits (110), Expect = 6e-06
Identities = 29/78 (37%), Positives = 47/78 (60%), Gaps = 9/78 (11%)
Query: 71 SAMEEMEFQRFVTPLKEALE----AYRREQKGKKEASEQKKKDKDKKTDSEEQDKSRDED 126
SA ++ +++ LKE E AYR KGK EA KK + T S+++++ DE+
Sbjct: 137 SAKDKQPYEQKAAKLKEKYEKDIAAYRA--KGKSEAG---KKGPGRPTGSKKKNEPEDEE 191
Query: 127 NDEDEERLEEEEQNEEEE 144
+E+EE +EEE++E+EE
Sbjct: 192 EEEEEEDEDEEEEDEDEE 209
>gi|11321591 high-mobility group box 2 [Homo sapiens]
Length = 209
Score = 47.0 bits (110), Expect = 6e-06
Identities = 29/78 (37%), Positives = 47/78 (60%), Gaps = 9/78 (11%)
Query: 71 SAMEEMEFQRFVTPLKEALE----AYRREQKGKKEASEQKKKDKDKKTDSEEQDKSRDED 126
SA ++ +++ LKE E AYR KGK EA KK + T S+++++ DE+
Sbjct: 137 SAKDKQPYEQKAAKLKEKYEKDIAAYRA--KGKSEAG---KKGPGRPTGSKKKNEPEDEE 191
Query: 127 NDEDEERLEEEEQNEEEE 144
+E+EE +EEE++E+EE
Sbjct: 192 EEEEEEDEDEEEEDEDEE 209
>gi|169210053 PREDICTED: hypothetical protein [Homo sapiens]
Length = 185
Score = 46.6 bits (109), Expect = 7e-06
Identities = 25/89 (28%), Positives = 48/89 (53%), Gaps = 3/89 (3%)
Query: 61 RKTLNASDVLSAMEEMEFQRFVTPLKEALEAYRREQKGKKEASEQKKKDKDKKTDSEEQD 120
+ L+A + LS ++ L E + ++E E+++K+++K+ D EE++
Sbjct: 88 KNDLSAGNRLSVARTAALVAEECSAQQGLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEE 147
Query: 121 KSRDEDNDEDEERLE---EEEQNEEEEVD 146
K +++ DE+EE E EE+ EEE+D
Sbjct: 148 KEEEKEEDEEEEEKEGKKMEEEKVEEEID 176
Score = 36.6 bits (83), Expect = 0.008
Identities = 26/87 (29%), Positives = 49/87 (56%), Gaps = 8/87 (9%)
Query: 59 GKRKTLNASDVLSAMEEMEFQRFVTPLKEALEAYRRE--QKGKKEASEQKKKDKDKKTDS 116
G R ++ + L A EE Q+ + +E +E E ++ K+E +K++D++ +
Sbjct: 94 GNRLSVARTAALVA-EECSAQQGLPVEEEEVEEEEEEVEEEEKEE-----EKEEDEEEEE 147
Query: 117 EEQDKSRDEDNDEDEERLEEEEQNEEE 143
+E++K DE+ +E E + EEE+ EEE
Sbjct: 148 KEEEKEEDEEEEEKEGKKMEEEKVEEE 174
Score = 35.4 bits (80), Expect = 0.017
Identities = 15/48 (31%), Positives = 32/48 (66%)
Query: 100 KEASEQKKKDKDKKTDSEEQDKSRDEDNDEDEERLEEEEQNEEEEVDN 147
+E S Q+ +++ EE+++ +E+ +E++E EEEE+ EEE+ ++
Sbjct: 108 EECSAQQGLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEED 155
>gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo
sapiens]
Length = 2168
Score = 46.6 bits (109), Expect = 7e-06
Identities = 32/150 (21%), Positives = 65/150 (43%), Gaps = 18/150 (12%)
Query: 11 PNAVITRIIKEALPDGVNISKEARSAISRAASVFVLYATSCANNFAMKGKRKTLNASDVL 70
PN VI +I+EA P + + +S I+ + S N + G+R N + V+
Sbjct: 494 PNGVIQSVIQEA-PLALTTKTKMQSKINENIAAASSTPFSSPVNLSTSGRRTPGNQTPVM 552
Query: 71 SA-----------------MEEMEFQRFVTPLKEALEAYRREQKGKKEASEQKKKDKDKK 113
+ + ++ Q P K +E +R + + + ++D++
Sbjct: 553 PSASPILHSQGKEKAVSNNVNPVKTQHHSHPAKSLVEQFRGTDSDIPSSKDSEDSNEDEE 612
Query: 114 TDSEEQDKSRDEDNDEDEERLEEEEQNEEE 143
D EE+D+ DED++ D+ + E + +E +
Sbjct: 613 EDDEEEDEEDDEDDESDDSQSESDSNSESD 642
Score = 33.5 bits (75), Expect = 0.066
Identities = 19/65 (29%), Positives = 31/65 (47%), Gaps = 1/65 (1%)
Query: 84 PLKEALEAYRREQKGKKEASEQKKKDKDKKTDSEEQDKS-RDEDNDEDEERLEEEEQNEE 142
PL ++ + ++ KK D D T S+ + D+D+ EE EEE+Q+ E
Sbjct: 221 PLDARVDKIKDKKPRKKAMESSSNSDSDSGTSSDTSSEGISSSDSDDLEEDEEEEDQSIE 280
Query: 143 EEVDN 147
E D+
Sbjct: 281 ESEDD 285
Score = 30.0 bits (66), Expect = 0.72
Identities = 16/68 (23%), Positives = 30/68 (44%), Gaps = 6/68 (8%)
Query: 84 PLKEALEAYRREQKGKKEASEQKKK------DKDKKTDSEEQDKSRDEDNDEDEERLEEE 137
P K+A+E+ +S+ + D + D EE+D+S +E D+D + E
Sbjct: 234 PRKKAMESSSNSDSDSGTSSDTSSEGISSSDSDDLEEDEEEEDQSIEESEDDDSDSESEA 293
Query: 138 EQNEEEEV 145
+ +V
Sbjct: 294 QHKSNNQV 301
Score = 29.6 bits (65), Expect = 0.95
Identities = 13/43 (30%), Positives = 26/43 (60%), Gaps = 1/43 (2%)
Query: 104 EQKKKDKDKKTDSEEQDKSRDEDNDEDEERLEEEEQNEEEEVD 146
++++K D D ++ D S D+ DED+E E++E + ++ D
Sbjct: 1289 KRRRKGGDSDYDDDDDDDS-DDQGDEDDEDEEDKEDKKGKKTD 1330
Score = 28.5 bits (62), Expect = 2.1
Identities = 16/67 (23%), Positives = 30/67 (44%), Gaps = 14/67 (20%)
Query: 94 REQKGKKEASEQKKKDKDKKTDSEEQDKSRDEDND--------------EDEERLEEEEQ 139
+EQ + + K KDKK + + S + D+D D + LEE+E+
Sbjct: 214 QEQSKNQPLDARVDKIKDKKPRKKAMESSSNSDSDSGTSSDTSSEGISSSDSDDLEEDEE 273
Query: 140 NEEEEVD 146
E++ ++
Sbjct: 274 EEDQSIE 280
Score = 28.5 bits (62), Expect = 2.1
Identities = 12/38 (31%), Positives = 23/38 (60%)
Query: 107 KKDKDKKTDSEEQDKSRDEDNDEDEERLEEEEQNEEEE 144
+K + K DS+ D D+ +D+ +E E+EE E+++
Sbjct: 1288 RKRRRKGGDSDYDDDDDDDSDDQGDEDDEDEEDKEDKK 1325
>gi|4506411 Ran GTPase activating protein 1 [Homo sapiens]
Length = 587
Score = 46.2 bits (108), Expect = 1e-05
Identities = 23/60 (38%), Positives = 38/60 (63%), Gaps = 3/60 (5%)
Query: 85 LKEALEAYRREQKGKKEASEQKKKDKDKKTDSEEQDKSRDEDNDEDEERLEEEEQNEEEE 144
L+E LE + K AS +D++++ + EE+++ +E+ +EDEE EEEE+ EEEE
Sbjct: 341 LQEVLEGFNM---AKVLASLSDDEDEEEEEEGEEEEEEAEEEEEEDEEEEEEEEEEEEEE 397
Score = 37.7 bits (86), Expect = 0.003
Identities = 19/59 (32%), Positives = 31/59 (52%)
Query: 86 KEALEAYRREQKGKKEASEQKKKDKDKKTDSEEQDKSRDEDNDEDEERLEEEEQNEEEE 144
+E E + +G A D+ + EE+ + +E+ +E+EE EEEE+ EEEE
Sbjct: 335 EEGCEQLQEVLEGFNMAKVLASLSDDEDEEEEEEGEEEEEEAEEEEEEDEEEEEEEEEE 393
Score = 33.1 bits (74), Expect = 0.086
Identities = 15/26 (57%), Positives = 20/26 (76%)
Query: 122 SRDEDNDEDEERLEEEEQNEEEEVDN 147
S DED +E+EE EEEE+ EEEE ++
Sbjct: 358 SDDEDEEEEEEGEEEEEEAEEEEEED 383
>gi|55956788 nucleolin [Homo sapiens]
Length = 710
Score = 45.8 bits (107), Expect = 1e-05
Identities = 24/65 (36%), Positives = 41/65 (63%), Gaps = 8/65 (12%)
Query: 86 KEALEAYRREQKGKKEA------SEQKKKDKDKKTDSEEQDKSRDEDNDEDEERLEEEEQ 139
+EA+E KGKK A ++ +D+D++ D E++D DED+++D++ +EEE+
Sbjct: 208 EEAMET--TPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDEDDEDDDDEDDEEEE 265
Query: 140 NEEEE 144
EEEE
Sbjct: 266 EEEEE 270
Score = 43.1 bits (100), Expect = 8e-05
Identities = 23/64 (35%), Positives = 35/64 (54%), Gaps = 14/64 (21%)
Query: 97 KGKKEASEQKKKDKDKKTDSE-EQDKSRDEDNDEDEERLE-------------EEEQNEE 142
KG K KK+D D++ D + E+D+ DED DEDE+ +E E+E +E+
Sbjct: 132 KGAKNGKNAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDED 191
Query: 143 EEVD 146
+E D
Sbjct: 192 DEDD 195
Score = 42.0 bits (97), Expect = 2e-04
Identities = 19/57 (33%), Positives = 35/57 (61%)
Query: 86 KEALEAYRREQKGKKEASEQKKKDKDKKTDSEEQDKSRDEDNDEDEERLEEEEQNEE 142
K+A + + K E ++++ D+D+ D +E D+ D+++DE+EE EEEE +E
Sbjct: 219 KKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDEDDEDDDDEDDEEEEEEEEEEPVKE 275
Score = 40.8 bits (94), Expect = 4e-04
Identities = 19/62 (30%), Positives = 34/62 (54%)
Query: 83 TPLKEALEAYRREQKGKKEASEQKKKDKDKKTDSEEQDKSRDEDNDEDEERLEEEEQNEE 142
TP K A K K A ++ +++ D+ D ++ + D+D+++DEE EEEE+
Sbjct: 214 TPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDEDDEDDDDEDDEEEEEEEEEEPV 273
Query: 143 EE 144
+E
Sbjct: 274 KE 275
Score = 37.0 bits (84), Expect = 0.006
Identities = 19/50 (38%), Positives = 32/50 (64%), Gaps = 2/50 (4%)
Query: 98 GKKEASEQKKKDKD-KKTDSEEQDKSRDEDNDEDEERLEEEEQNEEEEVD 146
GKK A+ K K+ K E+ D+ D+D++EDEE +E+E +E+E++
Sbjct: 123 GKKGAAIPAKGAKNGKNAKKEDSDEEEDDDSEEDEED-DEDEDEDEDEIE 171
Score = 36.6 bits (83), Expect = 0.008
Identities = 17/68 (25%), Positives = 37/68 (54%), Gaps = 16/68 (23%)
Query: 96 QKGKKEASEQKKKDKDKKTDSEEQDKSRDED----------------NDEDEERLEEEEQ 139
+ KKE S++++ D ++ + +++D+ DED DED+E E++E
Sbjct: 138 KNAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDEDDED 197
Query: 140 NEEEEVDN 147
++++E D+
Sbjct: 198 DDDDEEDD 205
Score = 33.1 bits (74), Expect = 0.086
Identities = 20/79 (25%), Positives = 38/79 (48%), Gaps = 17/79 (21%)
Query: 85 LKEALEAYRREQKGKKEASEQKKKDKDKKTDSEEQD-----------------KSRDEDN 127
+K A A E + ++ + + D D++ DSEE+ K+++
Sbjct: 175 MKAAAAAPASEDEDDEDDEDDEDDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAE 234
Query: 128 DEDEERLEEEEQNEEEEVD 146
DEDEE +E+E ++++E D
Sbjct: 235 DEDEEEDDEDEDDDDDEDD 253
Score = 30.8 bits (68), Expect = 0.42
Identities = 11/51 (21%), Positives = 29/51 (56%)
Query: 95 EQKGKKEASEQKKKDKDKKTDSEEQDKSRDEDNDEDEERLEEEEQNEEEEV 145
E + ++E E + D D+ + ++ + +E+ +E+EE ++E ++E+
Sbjct: 234 EDEDEEEDDEDEDDDDDEDDEDDDDEDDEEEEEEEEEEPVKEAPGKRKKEM 284
Score = 27.3 bits (59), Expect = 4.7
Identities = 18/65 (27%), Positives = 30/65 (46%), Gaps = 17/65 (26%)
Query: 95 EQKGKKEASEQKKKDKDKKTD---------------SEEQDKSRDEDN--DEDEERLEEE 137
E+ E E+ +D+D+ D SE++D DED+ D+D+E + E
Sbjct: 148 EEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDEDDEDDDDDEEDDSE 207
Query: 138 EQNEE 142
E+ E
Sbjct: 208 EEAME 212
>gi|115511012 coiled-coil domain containing 136 [Homo sapiens]
Length = 1154
Score = 45.8 bits (107), Expect = 1e-05
Identities = 33/111 (29%), Positives = 54/111 (48%), Gaps = 17/111 (15%)
Query: 53 NNFAMKGKRKTLNASDV----LSAMEEMEFQRFVTPLKEALEAYRREQKGKKEASEQKKK 108
N +K K+ T SD L + +E + + L+ +E++ K+E E+KK+
Sbjct: 990 NANGVKMKKVTKPCSDTSESDLETRKSLEVVLYYKASQRKLDGLAKEEEKKEEMEEEKKQ 1049
Query: 109 DKDKK------------TDSEEQDKSRD-EDNDEDEERLEEEEQNEEEEVD 146
K++ D EE + D E+N+ED+E E+EE +EEEE D
Sbjct: 1050 VKEEAKEQCGDELVAEPADPEEAKSTEDQEENEEDKEEEEKEEDSEEEEDD 1100
Score = 30.8 bits (68), Expect = 0.42
Identities = 15/54 (27%), Positives = 30/54 (55%), Gaps = 1/54 (1%)
Query: 87 EALEAYRREQKGKKEASEQKKKDKDKKTDSEEQDKSRDEDNDEDEERLEEEEQN 140
+ L A + + K +Q++ ++DK+ + +E+D S +E++D D EE N
Sbjct: 1060 DELVAEPADPEEAKSTEDQEENEEDKEEEEKEED-SEEEEDDADSSLESPEENN 1112
Score = 27.7 bits (60), Expect = 3.6
Identities = 23/99 (23%), Positives = 47/99 (47%), Gaps = 9/99 (9%)
Query: 28 NISKEARSAISRAASVFVLYATSCANNFAMKGK-------RKTLNASDVLSAMEEMEFQR 80
N +K+++ + + ++ V+Y A ++ + RK L A D+ +EEM+ +
Sbjct: 673 NRNKQSKLLMEQMQALQVMYDAGQAKQELLQQEQGRLLEERKRLQA-DLQLCLEEMQLLQ 731
Query: 81 FVTP-LKEALEAYRREQKGKKEASEQKKKDKDKKTDSEE 118
+P +K +LE+Y + ++E +K D D E
Sbjct: 732 VQSPSIKMSLESYGKSYGSMVPSNENCRKTYDTTVDDNE 770
>gi|239050813 lipoxygenase homology domains 1 isoform 1 [Homo
sapiens]
Length = 2211
Score = 45.1 bits (105), Expect = 2e-05
Identities = 23/73 (31%), Positives = 43/73 (58%), Gaps = 2/73 (2%)
Query: 70 LSAMEEMEFQRFVTPLKEALEAYRREQKGKKEASEQKKKDKDKKTDSEEQDKSRDEDNDE 129
L+ EE ++ L++ L+ R K K + ++K+K D++ + EE++ S E++
Sbjct: 908 LTPEEEARKKKEKDKLRQLLKKERL--KAKLQRKKKKRKGSDEEDEGEEEESSSSEESSS 965
Query: 130 DEERLEEEEQNEE 142
+EE +EEEE+ EE
Sbjct: 966 EEEEMEEEEEEEE 978
Score = 40.4 bits (93), Expect = 5e-04
Identities = 24/67 (35%), Positives = 40/67 (59%), Gaps = 4/67 (5%)
Query: 82 VTPLKEALEAYRRE---QKGKKEASEQK-KKDKDKKTDSEEQDKSRDEDNDEDEERLEEE 137
+TP +EA + ++ Q KKE + K ++ K K+ S+E+D+ +E++ EE EE
Sbjct: 908 LTPEEEARKKKEKDKLRQLLKKERLKAKLQRKKKKRKGSDEEDEGEEEESSSSEESSSEE 967
Query: 138 EQNEEEE 144
E+ EEEE
Sbjct: 968 EEMEEEE 974
Score = 33.1 bits (74), Expect = 0.086
Identities = 18/59 (30%), Positives = 35/59 (59%), Gaps = 2/59 (3%)
Query: 90 EAYRREQKGKKEASEQKKKDKDKKTDSEEQDKSRDEDND--EDEERLEEEEQNEEEEVD 146
EA ++++K K +K++ K K +++ K DE+++ E+E EE +EEEE++
Sbjct: 913 EARKKKEKDKLRQLLKKERLKAKLQRKKKKRKGSDEEDEGEEEESSSSEESSSEEEEME 971
>gi|56806673 high-mobility group box 1-like 1 [Homo sapiens]
Length = 211
Score = 44.7 bits (104), Expect = 3e-05
Identities = 37/123 (30%), Positives = 60/123 (48%), Gaps = 20/123 (16%)
Query: 35 SAISRAASVFVLYATSCANNFAMKGKRKTLNASDVLSAMEEM----------EFQRFVTP 84
+A R S F L+ + +KG+ L+ DV + EM ++
Sbjct: 93 NAPKRPPSAFFLFCSEYHPK--IKGEHPGLSIGDVAKKLGEMWNNTAADDKQPGEKKAAK 150
Query: 85 LKEALE----AYRREQKGKKEASEQK--KKDKDKKTDSEEQDKSRDEDNDEDEERLEEEE 138
LKE E AY + KGK EA+++ K +K KK EE+D+ +ED +E++E EE++
Sbjct: 151 LKEKYEKDIAAY--QAKGKPEAAKKGVVKAEKSKKKKEEEEDEEDEEDEEEEDEEDEEDD 208
Query: 139 QNE 141
+E
Sbjct: 209 DDE 211
>gi|22749303 hypothetical protein LOC196477 [Homo sapiens]
Length = 406
Score = 44.7 bits (104), Expect = 3e-05
Identities = 26/59 (44%), Positives = 37/59 (62%), Gaps = 3/59 (5%)
Query: 90 EAYRREQKGKKEASEQKKKDKDKKT---DSEEQDKSRDEDNDEDEERLEEEEQNEEEEV 145
E Y +E KEASE++++ +D++ D EE++ E +E EE LEEEE EEEEV
Sbjct: 288 EEYDQEVCDAKEASEEEEEVEDEEEEVEDEEEEEVEEAEYVEEGEEELEEEELEEEEEV 346
Score = 38.5 bits (88), Expect = 0.002
Identities = 21/71 (29%), Positives = 42/71 (59%), Gaps = 1/71 (1%)
Query: 74 EEMEFQRFVTPLKEALEAYRREQKGKKEASEQKKKDKDKKTDSEE-QDKSRDEDNDEDEE 132
+E E+ + V KEA E + ++E ++++++ ++ EE +++ +E+ +E+EE
Sbjct: 286 DEEEYDQEVCDAKEASEEEEEVEDEEEEVEDEEEEEVEEAEYVEEGEEELEEEELEEEEE 345
Query: 133 RLEEEEQNEEE 143
LEE EQ EE
Sbjct: 346 VLEENEQRGEE 356
Score = 37.7 bits (86), Expect = 0.003
Identities = 20/47 (42%), Positives = 28/47 (59%), Gaps = 1/47 (2%)
Query: 101 EASEQKKKDKDKKTDSEEQD-KSRDEDNDEDEERLEEEEQNEEEEVD 146
E E+KK D +++ D E D K E+ +E E+ EE E EEEEV+
Sbjct: 277 EEEEEKKNDDEEEYDQEVCDAKEASEEEEEVEDEEEEVEDEEEEEVE 323
Score = 35.8 bits (81), Expect = 0.013
Identities = 36/135 (26%), Positives = 62/135 (45%), Gaps = 15/135 (11%)
Query: 27 VNISKEARSAISRAASVFVLYATSCANNFAMKGKRKTLNASDVLSAMEEMEFQRFVTPLK 86
V +EA A S A S N+ G ++T + L + F +
Sbjct: 207 VERQQEALRAQKATVSGEASPARSSGNDAPPGGSKETWGLQETLYGFVQNPSLAFSPNPE 266
Query: 87 E--ALEAYRREQKGKKEASEQKKKDK---DKKTDSEEQDKSRDEDN---DEDEERLEE-- 136
E +L E++ +K+ ++++ D+ D K SEE+++ DE+ DE+EE +EE
Sbjct: 267 ENQSLAPLLVEEEEEKKNDDEEEYDQEVCDAKEASEEEEEVEDEEEEVEDEEEEEVEEAE 326
Query: 137 -----EEQNEEEEVD 146
EE+ EEEE++
Sbjct: 327 YVEEGEEELEEEELE 341
>gi|46852388 cell-cycle and apoptosis regulatory protein 1 [Homo
sapiens]
Length = 1150
Score = 44.3 bits (103), Expect = 4e-05
Identities = 16/50 (32%), Positives = 35/50 (70%)
Query: 95 EQKGKKEASEQKKKDKDKKTDSEEQDKSRDEDNDEDEERLEEEEQNEEEE 144
+ K KKE +++KK+ +K DS++ D++ +++N ++ + +E EE +EE+
Sbjct: 834 DDKDKKEDRDERKKEDKRKDDSKDDDETEEDNNQDEYDPMEAEEAEDEED 883
Score = 41.6 bits (96), Expect = 2e-04
Identities = 23/84 (27%), Positives = 45/84 (53%), Gaps = 3/84 (3%)
Query: 62 KTLNASDVLSAMEEMEFQRFVTPLKEALEAYRREQ-KGKKEASEQKKKDKDKKTDSEEQD 120
KT+ +D+ +E LK L A +Q K +++ EQK+ +K +K + E+ D
Sbjct: 637 KTMKVNDLRKELESRALSS--KGLKSQLIARLTKQLKVEEQKEEQKELEKSEKEEDEDDD 694
Query: 121 KSRDEDNDEDEERLEEEEQNEEEE 144
+ ++D +E+E + +EE + + E
Sbjct: 695 RKSEDDKEEEERKRQEEIERQRRE 718
Score = 40.4 bits (93), Expect = 5e-04
Identities = 21/73 (28%), Positives = 41/73 (56%), Gaps = 10/73 (13%)
Query: 85 LKEALEAYRREQKGKKEASEQKKKDKDKKTDSEE-------QDKSRDEDNDE---DEERL 134
L E + +++K KK+ + KK+++D +TD + DK + ED DE +++R
Sbjct: 793 LPEKEDKKEKDKKSKKDERKDKKEERDDETDEPKPKRRKSGDDKDKKEDRDERKKEDKRK 852
Query: 135 EEEEQNEEEEVDN 147
++ + ++E E DN
Sbjct: 853 DDSKDDDETEEDN 865
Score = 37.7 bits (86), Expect = 0.003
Identities = 22/73 (30%), Positives = 39/73 (53%), Gaps = 8/73 (10%)
Query: 82 VTPLKEALEAYRREQKGKKEA-----SEQKKKDKDKKTDSEEQDKSRDEDNDED---EER 133
V L++ LE+ KG K ++Q K ++ K+ E + ++ED D+D E+
Sbjct: 641 VNDLRKELESRALSSKGLKSQLIARLTKQLKVEEQKEEQKELEKSEKEEDEDDDRKSEDD 700
Query: 134 LEEEEQNEEEEVD 146
EEEE+ +EE++
Sbjct: 701 KEEEERKRQEEIE 713
Score = 37.4 bits (85), Expect = 0.005
Identities = 25/72 (34%), Positives = 40/72 (55%), Gaps = 15/72 (20%)
Query: 86 KEALEAYRREQKGKK--EASEQKKK------DKDKKTDSEE---QDKSRDEDNDEDEERL 134
K++ + R+++K ++ E E K K DKDKK D +E +DK +D+ D+D
Sbjct: 804 KKSKKDERKDKKEERDDETDEPKPKRRKSGDDKDKKEDRDERKKEDKRKDDSKDDD---- 859
Query: 135 EEEEQNEEEEVD 146
E EE N ++E D
Sbjct: 860 ETEEDNNQDEYD 871
Score = 32.0 bits (71), Expect = 0.19
Identities = 16/52 (30%), Positives = 29/52 (55%), Gaps = 3/52 (5%)
Query: 94 REQKGKKEASEQKKKDKDKKTDSEEQDKSRDEDNDEDEERLEEEEQNEEEEV 145
R+++ K++ + KD D+ + QD + D E EE +EE+ +EEE+
Sbjct: 842 RDERKKEDKRKDDSKDDDETEEDNNQD---EYDPMEAEEAEDEEDDRDEEEM 890
>gi|167614488 TBC1 domain family, member 10B [Homo sapiens]
Length = 808
Score = 44.3 bits (103), Expect = 4e-05
Identities = 18/62 (29%), Positives = 44/62 (70%), Gaps = 1/62 (1%)
Query: 83 TPLKEALEAYRREQKGKKEASEQKKKDKDKKTDSEEQDKSRDEDNDEDEERLEEEEQNEE 142
TPL + E ++E++ +K+ E++K++K+++ + ++Q+K R E +++ E+ E+E Q +E
Sbjct: 713 TPLGSSKETRKQEKERQKQEKERQKQEKEREKERQKQEKER-EKQEKEREKQEKERQKQE 771
Query: 143 EE 144
++
Sbjct: 772 KK 773
Score = 29.6 bits (65), Expect = 0.95
Identities = 12/48 (25%), Positives = 30/48 (62%)
Query: 86 KEALEAYRREQKGKKEASEQKKKDKDKKTDSEEQDKSRDEDNDEDEER 133
K+ E ++E++ +KE +Q+K+ + ++ + E+Q+K R + + + R
Sbjct: 730 KQEKERQKQEKEREKERQKQEKEREKQEKEREKQEKERQKQEKKAQGR 777
>gi|24497618 ATPase family, AAA domain containing 2 [Homo sapiens]
Length = 1390
Score = 43.9 bits (102), Expect = 5e-05
Identities = 31/131 (23%), Positives = 56/131 (42%), Gaps = 18/131 (13%)
Query: 14 VITRIIKEALPDGVNISKEARSAISRAASVFVLYATSCAN-NFAMKGKRKTLNASDVLSA 72
+IT + L ++ K R + + V T +N N +GK+K + +D
Sbjct: 176 LITNTAEAVLQKMDDMKKMRRQRMRELEDLGVFNETEESNLNMYTRGKQKDIQRTD---- 231
Query: 73 MEEMEFQRFVTPLKEALEAYRREQKGKKEASEQKKKDKDKKTDSEEQDKSRDEDNDEDEE 132
+E + + +E +Q+ +D + D E+ D D+D+D+D+E
Sbjct: 232 -------------EETTDNQEGSVESSEEGEDQEHEDDGEDEDDEDDDDDDDDDDDDDDE 278
Query: 133 RLEEEEQNEEE 143
E+EE EEE
Sbjct: 279 DDEDEEDGEEE 289
Score = 36.6 bits (83), Expect = 0.008
Identities = 16/88 (18%), Positives = 48/88 (54%), Gaps = 1/88 (1%)
Query: 60 KRKTLNASDVLSAMEEMEFQRFVTPLKEALEAYRREQKGKKEAS-EQKKKDKDKKTDSEE 118
+ + L V + EE + ++ ++ E +E S E ++ +D++ + +
Sbjct: 198 RMRELEDLGVFNETEESNLNMYTRGKQKDIQRTDEETTDNQEGSVESSEEGEDQEHEDDG 257
Query: 119 QDKSRDEDNDEDEERLEEEEQNEEEEVD 146
+D+ ++D+D+D++ +++++++E+E D
Sbjct: 258 EDEDDEDDDDDDDDDDDDDDEDDEDEED 285
>gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]
Length = 709
Score = 43.9 bits (102), Expect = 5e-05
Identities = 21/55 (38%), Positives = 35/55 (63%), Gaps = 5/55 (9%)
Query: 95 EQKGKKEASEQKKKDKDKKTDSE-----EQDKSRDEDNDEDEERLEEEEQNEEEE 144
+++G +E++ ++D + D E E+D+ DED +E+EE EEEE+ EEEE
Sbjct: 192 DEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEE 246
Score = 41.6 bits (96), Expect = 2e-04
Identities = 18/49 (36%), Positives = 33/49 (67%)
Query: 95 EQKGKKEASEQKKKDKDKKTDSEEQDKSRDEDNDEDEERLEEEEQNEEE 143
E++G +E E+ ++ ++ + EE D+ +E+ +E+EE EEEE+ EEE
Sbjct: 201 EEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEE 249
Score = 40.4 bits (93), Expect = 5e-04
Identities = 17/52 (32%), Positives = 32/52 (61%)
Query: 95 EQKGKKEASEQKKKDKDKKTDSEEQDKSRDEDNDEDEERLEEEEQNEEEEVD 146
E+ +++ E ++ ++D + D E + +E+ +E+EE EEEE+ EE E D
Sbjct: 202 EEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQD 253
Score = 40.4 bits (93), Expect = 5e-04
Identities = 16/55 (29%), Positives = 33/55 (60%)
Query: 90 EAYRREQKGKKEASEQKKKDKDKKTDSEEQDKSRDEDNDEDEERLEEEEQNEEEE 144
E + + +E E ++D++ D EE+++ +E+ +E+EE EE EQ+E ++
Sbjct: 203 EGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQ 257
Score = 39.3 bits (90), Expect = 0.001
Identities = 15/55 (27%), Positives = 39/55 (70%), Gaps = 1/55 (1%)
Query: 90 EAYRREQKGKKEASEQKKKDKDKKTDSEEQDKSRDEDNDEDEERLEEEEQNEEEE 144
E +++ +++A E ++ D+D + + EE+++ +E+ +E+EE E++E++++EE
Sbjct: 207 EDVEEDEEVEEDAEEDEEVDEDGE-EEEEEEEEEEEEEEEEEEEYEQDERDQKEE 260
Score = 33.9 bits (76), Expect = 0.050
Identities = 18/60 (30%), Positives = 31/60 (51%), Gaps = 11/60 (18%)
Query: 96 QKGKKEASEQKKKDKDKKTDSEEQDKSRDEDNDED-----------EERLEEEEQNEEEE 144
+ G +S+++ + + + + E+D DE+ +ED EE EEEE+ EEEE
Sbjct: 184 ETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEE 243
Score = 32.7 bits (73), Expect = 0.11
Identities = 17/57 (29%), Positives = 30/57 (52%), Gaps = 2/57 (3%)
Query: 90 EAYRREQKGKKEASEQKKKDKDKKTDSEEQDKSRDEDNDEDEERLEEEEQNEEEEVD 146
E E+ G + ++ ++E +++ +ED +EDEE EE+ E+EEVD
Sbjct: 172 EEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEE--VEEDAEEDEEVD 226
Score = 28.9 bits (63), Expect = 1.6
Identities = 17/62 (27%), Positives = 32/62 (51%), Gaps = 4/62 (6%)
Query: 89 LEAYRREQKGKKEASEQKKKDK---DKKTDSEEQDKSRDEDNDEDEERLEEE-EQNEEEE 144
LE RR + + + E+ ++ D +T S + + + +EE +EE+ E++EE E
Sbjct: 157 LEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVE 216
Query: 145 VD 146
D
Sbjct: 217 ED 218
>gi|83716024 kinesin family member 21B [Homo sapiens]
Length = 1624
Score = 43.9 bits (102), Expect = 5e-05
Identities = 30/131 (22%), Positives = 70/131 (53%), Gaps = 8/131 (6%)
Query: 19 IKEALPDGVNISKEARSAISRAA--SVFVLYATSCANNFAMKGKRKTLNASDVLSAMEEM 76
++ L + +++ R ++SRA+ S + L A+ A F +AS+V+ ++
Sbjct: 488 LRTKLLESEAMNESLRRSLSRASARSPYSLGASPAAPAFGGSPASSMEDASEVIRRAKQ- 546
Query: 77 EFQRFVTPLKEALEAYRREQKGKKEASEQKKKDKDKKTDSEEQDKSRDEDNDEDEERLEE 136
+ +R + E +R + +KEA +++ K + + ++ +++++ +E+ + DE EE
Sbjct: 547 DLERL-----KKKEVRQRRKSPEKEAFKKRAKLQQENSEETDENEAEEEEEERDESGCEE 601
Query: 137 EEQNEEEEVDN 147
EE E+E+ D+
Sbjct: 602 EEGREDEDEDS 612
>gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]
Length = 727
Score = 43.9 bits (102), Expect = 5e-05
Identities = 21/55 (38%), Positives = 35/55 (63%), Gaps = 5/55 (9%)
Query: 95 EQKGKKEASEQKKKDKDKKTDSE-----EQDKSRDEDNDEDEERLEEEEQNEEEE 144
+++G +E++ ++D + D E E+D+ DED +E+EE EEEE+ EEEE
Sbjct: 192 DEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEE 246
Score = 41.6 bits (96), Expect = 2e-04
Identities = 18/49 (36%), Positives = 33/49 (67%)
Query: 95 EQKGKKEASEQKKKDKDKKTDSEEQDKSRDEDNDEDEERLEEEEQNEEE 143
E++G +E E+ ++ ++ + EE D+ +E+ +E+EE EEEE+ EEE
Sbjct: 201 EEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEE 249
Score = 40.4 bits (93), Expect = 5e-04
Identities = 17/52 (32%), Positives = 32/52 (61%)
Query: 95 EQKGKKEASEQKKKDKDKKTDSEEQDKSRDEDNDEDEERLEEEEQNEEEEVD 146
E+ +++ E ++ ++D + D E + +E+ +E+EE EEEE+ EE E D
Sbjct: 202 EEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQD 253
Score = 40.4 bits (93), Expect = 5e-04
Identities = 16/55 (29%), Positives = 33/55 (60%)
Query: 90 EAYRREQKGKKEASEQKKKDKDKKTDSEEQDKSRDEDNDEDEERLEEEEQNEEEE 144
E + + +E E ++D++ D EE+++ +E+ +E+EE EE EQ+E ++
Sbjct: 203 EGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQ 257
Score = 39.3 bits (90), Expect = 0.001
Identities = 15/55 (27%), Positives = 39/55 (70%), Gaps = 1/55 (1%)
Query: 90 EAYRREQKGKKEASEQKKKDKDKKTDSEEQDKSRDEDNDEDEERLEEEEQNEEEE 144
E +++ +++A E ++ D+D + + EE+++ +E+ +E+EE E++E++++EE
Sbjct: 207 EDVEEDEEVEEDAEEDEEVDEDGE-EEEEEEEEEEEEEEEEEEEYEQDERDQKEE 260
Score = 33.9 bits (76), Expect = 0.050
Identities = 18/60 (30%), Positives = 31/60 (51%), Gaps = 11/60 (18%)
Query: 96 QKGKKEASEQKKKDKDKKTDSEEQDKSRDEDNDED-----------EERLEEEEQNEEEE 144
+ G +S+++ + + + + E+D DE+ +ED EE EEEE+ EEEE
Sbjct: 184 ETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEE 243
Score = 32.7 bits (73), Expect = 0.11
Identities = 17/57 (29%), Positives = 30/57 (52%), Gaps = 2/57 (3%)
Query: 90 EAYRREQKGKKEASEQKKKDKDKKTDSEEQDKSRDEDNDEDEERLEEEEQNEEEEVD 146
E E+ G + ++ ++E +++ +ED +EDEE EE+ E+EEVD
Sbjct: 172 EEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEE--VEEDAEEDEEVD 226
Score = 28.9 bits (63), Expect = 1.6
Identities = 17/62 (27%), Positives = 32/62 (51%), Gaps = 4/62 (6%)
Query: 89 LEAYRREQKGKKEASEQKKKDK---DKKTDSEEQDKSRDEDNDEDEERLEEE-EQNEEEE 144
LE RR + + + E+ ++ D +T S + + + +EE +EE+ E++EE E
Sbjct: 157 LEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVE 216
Query: 145 VD 146
D
Sbjct: 217 ED 218
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.303 0.122 0.310
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 5,352,236
Number of Sequences: 37866
Number of extensions: 257609
Number of successful extensions: 22179
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1103
Number of HSP's successfully gapped in prelim test: 439
Number of HSP's that attempted gapping in prelim test: 4063
Number of HSP's gapped (non-prelim): 9872
length of query: 147
length of database: 18,247,518
effective HSP length: 93
effective length of query: 54
effective length of database: 14,725,980
effective search space: 795202920
effective search space used: 795202920
T: 11
A: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.8 bits)
S2: 57 (26.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.