Search of human proteins with 224282123

Search of human proteins with 224282123

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|224282123 tRNA-yW synthesizing protein 1 homolog B isoform 1
[Homo sapiens]
         (668 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|224282123 tRNA-yW synthesizing protein 1 homolog B isoform 1 ...  1384   0.0  
gi|50726981 radical S-adenosyl methionine and flavodoxin domains...  1277   0.0  
gi|224282125 tRNA-yW synthesizing protein 1 homolog B isoform 2 ...   733   0.0  
gi|127139033 cytochrome P450 reductase [Homo sapiens]                  83   9e-16
gi|103471997 DNA-directed RNA polymerase I A [Homo sapiens]            46   1e-04
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom...    44   6e-04
gi|155030232 proline, glutamic acid and leucine rich protein 1 [...    42   0.002
gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]     40   0.007
gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]     40   0.007
gi|83716024 kinesin family member 21B [Homo sapiens]                   40   0.007
gi|10835173 nitric oxide synthase 1, neuronal [Homo sapiens]           39   0.015
gi|148746195 trichohyalin [Homo sapiens]                               39   0.015
gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof...    39   0.020
gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isof...    39   0.020
gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isof...    39   0.020
gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isof...    39   0.020
gi|16332360 cell division cycle 2-like 1 (PITSLRE proteins) isof...    39   0.020
gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isof...    39   0.020
gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]           39   0.020
gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]           39   0.020
gi|239756368 PREDICTED: similar to acidic (leucine-rich) nuclear...    38   0.026
gi|239750893 PREDICTED: similar to acidic (leucine-rich) nuclear...    38   0.026
gi|4759128 solute carrier family 24 (sodium/potassium/calcium ex...    38   0.026
gi|21735415 centromere protein B [Homo sapiens]                        38   0.034
gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo sap...    38   0.034
gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo sap...    38   0.034
gi|13569879 acidic (leucine-rich) nuclear phosphoprotein 32 fami...    38   0.034
gi|210147569 acidic (leucine-rich) nuclear phosphoprotein 32 fam...    38   0.034
gi|210147571 acidic (leucine-rich) nuclear phosphoprotein 32 fam...    38   0.034
gi|239050813 lipoxygenase homology domains 1 isoform 1 [Homo sap...    37   0.045

>gi|224282123 tRNA-yW synthesizing protein 1 homolog B isoform 1
           [Homo sapiens]
          Length = 668

 Score = 1384 bits (3583), Expect = 0.0
 Identities = 668/668 (100%), Positives = 668/668 (100%)

Query: 1   MDPSADTWDLSSPLISLWINRFYIYLGFAVSISLWICVQIVIEMQGFATVLAEAVTSLDL 60
           MDPSADTWDLSSPLISLWINRFYIYLGFAVSISLWICVQIVIEMQGFATVLAEAVTSLDL
Sbjct: 1   MDPSADTWDLSSPLISLWINRFYIYLGFAVSISLWICVQIVIEMQGFATVLAEAVTSLDL 60

Query: 61  PVAIINLKEYDPDDHLIEEVTSKNVCVFLVATYTDGLPTESAEWFCKWLEEASIDFRFGK 120
           PVAIINLKEYDPDDHLIEEVTSKNVCVFLVATYTDGLPTESAEWFCKWLEEASIDFRFGK
Sbjct: 61  PVAIINLKEYDPDDHLIEEVTSKNVCVFLVATYTDGLPTESAEWFCKWLEEASIDFRFGK 120

Query: 121 TYLKGMRDAVFGLGNSAYASHFNKVGKNVDKWLWMLGVHRVMSRGEGDCDVVKSKHGSIE 180
           TYLKGMRDAVFGLGNSAYASHFNKVGKNVDKWLWMLGVHRVMSRGEGDCDVVKSKHGSIE
Sbjct: 121 TYLKGMRDAVFGLGNSAYASHFNKVGKNVDKWLWMLGVHRVMSRGEGDCDVVKSKHGSIE 180

Query: 181 ANFRAWKTKFISQLQALQKGERKKSCGGHCKKGKCESHQHGSEEREEGSQEQDELHHRDT 240
           ANFRAWKTKFISQLQALQKGERKKSCGGHCKKGKCESHQHGSEEREEGSQEQDELHHRDT
Sbjct: 181 ANFRAWKTKFISQLQALQKGERKKSCGGHCKKGKCESHQHGSEEREEGSQEQDELHHRDT 240

Query: 241 KEEEPFESSSEEEFGGEDHQSLNSIVDVEDLGKIMDHVKKEKREKEQQEEKSGLFRNMGR 300
           KEEEPFESSSEEEFGGEDHQSLNSIVDVEDLGKIMDHVKKEKREKEQQEEKSGLFRNMGR
Sbjct: 241 KEEEPFESSSEEEFGGEDHQSLNSIVDVEDLGKIMDHVKKEKREKEQQEEKSGLFRNMGR 300

Query: 301 NEDGERRAMITPALREALTKQVDAPRERSLLQTHILWNESHRCMETTPSLACANKCVFCW 360
           NEDGERRAMITPALREALTKQVDAPRERSLLQTHILWNESHRCMETTPSLACANKCVFCW
Sbjct: 301 NEDGERRAMITPALREALTKQVDAPRERSLLQTHILWNESHRCMETTPSLACANKCVFCW 360

Query: 361 WHHNNPVGTEWLWKMDQPEMILKEAIENHQNMIKQFKGVPGVKAERFEEGMTVKHCALSL 420
           WHHNNPVGTEWLWKMDQPEMILKEAIENHQNMIKQFKGVPGVKAERFEEGMTVKHCALSL
Sbjct: 361 WHHNNPVGTEWLWKMDQPEMILKEAIENHQNMIKQFKGVPGVKAERFEEGMTVKHCALSL 420

Query: 421 VGEPIMYPEINRFLKLLHQCKISSFLVTNAQFPAEIRNLEPVTQLYVSVDASTKDSLKKI 480
           VGEPIMYPEINRFLKLLHQCKISSFLVTNAQFPAEIRNLEPVTQLYVSVDASTKDSLKKI
Sbjct: 421 VGEPIMYPEINRFLKLLHQCKISSFLVTNAQFPAEIRNLEPVTQLYVSVDASTKDSLKKI 480

Query: 481 DRPLFKDFWQQFLDSLKALAVKQQRTVYRLTLVKAWNVDELQAYAQLVSLGNPDFIEVKG 540
           DRPLFKDFWQQFLDSLKALAVKQQRTVYRLTLVKAWNVDELQAYAQLVSLGNPDFIEVKG
Sbjct: 481 DRPLFKDFWQQFLDSLKALAVKQQRTVYRLTLVKAWNVDELQAYAQLVSLGNPDFIEVKG 540

Query: 541 VTYCRESSASSLTMAHVPWHEEVVQFVRELVDLIPEYEIACEHEHSNCLLIAHRKFKIGG 600
           VTYCRESSASSLTMAHVPWHEEVVQFVRELVDLIPEYEIACEHEHSNCLLIAHRKFKIGG
Sbjct: 541 VTYCRESSASSLTMAHVPWHEEVVQFVRELVDLIPEYEIACEHEHSNCLLIAHRKFKIGG 600

Query: 601 EWWTWIDYNRFQELIQEYEDSGGSKTFSAKDYMARTPHWALFGANERSFDPKDTRHQRKN 660
           EWWTWIDYNRFQELIQEYEDSGGSKTFSAKDYMARTPHWALFGANERSFDPKDTRHQRKN
Sbjct: 601 EWWTWIDYNRFQELIQEYEDSGGSKTFSAKDYMARTPHWALFGANERSFDPKDTRHQRKN 660

Query: 661 KSKAISGC 668
           KSKAISGC
Sbjct: 661 KSKAISGC 668


>gi|50726981 radical S-adenosyl methionine and flavodoxin domains 1
           [Homo sapiens]
          Length = 732

 Score = 1277 bits (3305), Expect = 0.0
 Identities = 638/732 (87%), Positives = 644/732 (87%), Gaps = 64/732 (8%)

Query: 1   MDPSADTWDLSSPLISLWINRFYIYLGFAVSISLWICVQIVIEMQG-------------- 46
           MDPSADTWDL SPLISLWINRFYIYLGFAVSISLWICVQIVI+ QG              
Sbjct: 1   MDPSADTWDLFSPLISLWINRFYIYLGFAVSISLWICVQIVIKTQGKNLQEKSVPKAAQD 60

Query: 47  --------------------------------FATVLAEAVTSLDLPVAIINLKEYDPDD 74
                                           FATVLAEAVTSLDLPVAIINLKEYDPDD
Sbjct: 61  LMTNGYVSLQEKDIFVSGVKIFYGSQTGTAKGFATVLAEAVTSLDLPVAIINLKEYDPDD 120

Query: 75  HLIEEVTSKNVCVFLVATYTDGLPTESAEWFCKWLEEASIDFRFGKTYLKGMRDAVFGLG 134
           HLIEEVTSKNVCVFLVATYTDGLPTESAEWFCKWLEEASIDFRFGKTYLKGMR AVFGLG
Sbjct: 121 HLIEEVTSKNVCVFLVATYTDGLPTESAEWFCKWLEEASIDFRFGKTYLKGMRYAVFGLG 180

Query: 135 NSAYASHFNKVGKNVDKWLWMLGVHRVMSRGEGDCDVVKSKHGSIEANFRAWKTKFISQL 194
           NSAYASHFNKVGKNVDKWLWMLG HRVMSRGEGDCDVVKSKHGSIEA+FRAWKTKFISQL
Sbjct: 181 NSAYASHFNKVGKNVDKWLWMLGAHRVMSRGEGDCDVVKSKHGSIEADFRAWKTKFISQL 240

Query: 195 QALQKGERKKSCGGHCKKGKCESHQHGSEEREEGSQEQDELHHRDTKEEEPFESSSEEEF 254
           QALQKGERKKSCGGHCKKGKCESHQHGSEEREEGS EQDELHHRDT+EEEPFESSSEEEF
Sbjct: 241 QALQKGERKKSCGGHCKKGKCESHQHGSEEREEGSHEQDELHHRDTEEEEPFESSSEEEF 300

Query: 255 GGEDHQSLNSIVDVEDLGKIMDHVKKEKREKEQQEEKSGLFRNMGRNEDGERRAMITPAL 314
           GGEDHQSLNSIVDVEDLGKIMDHVKKEKREKEQQEEKSGLFRNMGRNEDGERRAMITPAL
Sbjct: 301 GGEDHQSLNSIVDVEDLGKIMDHVKKEKREKEQQEEKSGLFRNMGRNEDGERRAMITPAL 360

Query: 315 REALTKQ-----------------VDAPRERSLLQTHILWN-ESHRCMETTPSLACANKC 356
           REALTKQ                     R R     H  +  ESHRCMETTPSLACANKC
Sbjct: 361 REALTKQGYQLIGSHSGVKLCRWTKSMLRGRGGCYKHTFYGIESHRCMETTPSLACANKC 420

Query: 357 VFCWWHHNNPVGTEWLWKMDQPEMILKEAIENHQNMIKQFKGVPGVKAERFEEGMTVKHC 416
           VFCW HH NPVGTEW WKMDQPEMILKEAIENHQNMIKQFKGVPGVKAERFEEGMTVKHC
Sbjct: 421 VFCWRHHTNPVGTEWRWKMDQPEMILKEAIENHQNMIKQFKGVPGVKAERFEEGMTVKHC 480

Query: 417 ALSLVGEPIMYPEINRFLKLLHQCKISSFLVTNAQFPAEIRNLEPVTQLYVSVDASTKDS 476
           ALSLVGEPIMYPEINRFLKLLHQCKISSFLVTNAQFPAEIRNLEPVTQLYVSVDASTKDS
Sbjct: 481 ALSLVGEPIMYPEINRFLKLLHQCKISSFLVTNAQFPAEIRNLEPVTQLYVSVDASTKDS 540

Query: 477 LKKIDRPLFKDFWQQFLDSLKALAVKQQRTVYRLTLVKAWNVDELQAYAQLVSLGNPDFI 536
           LKKIDRPLFKDFWQ+FLDSLKALAVKQQRTVYRLTLVKAWNVDELQAYAQLVSLGNPDFI
Sbjct: 541 LKKIDRPLFKDFWQRFLDSLKALAVKQQRTVYRLTLVKAWNVDELQAYAQLVSLGNPDFI 600

Query: 537 EVKGVTYCRESSASSLTMAHVPWHEEVVQFVRELVDLIPEYEIACEHEHSNCLLIAHRKF 596
           EVKGVTYC ESSASSLTMAHVPWHEEVVQFV ELVDLIPEYEIACEHEHSNCLLIAHRKF
Sbjct: 601 EVKGVTYCGESSASSLTMAHVPWHEEVVQFVHELVDLIPEYEIACEHEHSNCLLIAHRKF 660

Query: 597 KIGGEWWTWIDYNRFQELIQEYEDSGGSKTFSAKDYMARTPHWALFGANERSFDPKDTRH 656
           KIGGEWWTWIDYNRFQELIQEYEDSGGSKTFSAKDYMARTPHWALFGA+ER FDPKDTRH
Sbjct: 661 KIGGEWWTWIDYNRFQELIQEYEDSGGSKTFSAKDYMARTPHWALFGASERGFDPKDTRH 720

Query: 657 QRKNKSKAISGC 668
           QRKNKSKAISGC
Sbjct: 721 QRKNKSKAISGC 732


>gi|224282125 tRNA-yW synthesizing protein 1 homolog B isoform 2
           [Homo sapiens]
          Length = 471

 Score =  733 bits (1892), Expect = 0.0
 Identities = 361/386 (93%), Positives = 365/386 (94%), Gaps = 9/386 (2%)

Query: 230 QEQDELHHRDTKEEEPFESSSEEEFGGEDHQSLNSIVDVEDLGKIMDHVKKEKREKEQQE 289
           +E D   H   +EEEPFESSSEEEFGGEDHQSLNSIVDVEDLGKIMDHVKKEKREKEQQE
Sbjct: 68  KEYDPDDHLIEEEEEPFESSSEEEFGGEDHQSLNSIVDVEDLGKIMDHVKKEKREKEQQE 127

Query: 290 EKSGLFRNMGRNEDGERRAMITPALREALTKQVDAPRERSLLQTHILWNESHRCMETTPS 349
           EKSGLFRNMGRNEDGERRAMITPALREALTKQVDAPRERSLLQTHILWNESHRCMETTPS
Sbjct: 128 EKSGLFRNMGRNEDGERRAMITPALREALTKQVDAPRERSLLQTHILWNESHRCMETTPS 187

Query: 350 LACANKCVFCWWHHNNPVGTEWLWKMDQPEMILKEAIENHQNMIKQFKGVPGVKAERFEE 409
           LACANKCVFCWWHHNNPVGTEW WKMDQPEMILKEAIENHQNMIKQFKGVPGVKAERFEE
Sbjct: 188 LACANKCVFCWWHHNNPVGTEWWWKMDQPEMILKEAIENHQNMIKQFKGVPGVKAERFEE 247

Query: 410 GMTVKHCALSLVGEPIMYPEINRFLKLLHQCKISSFLVTNAQFPAEIRNLEPVTQLYVSV 469
           GMTVKHCALSLVGEPIMYPEINRFLKLLHQCKISSFLVTNAQFPAEIRNLEPVTQLYVSV
Sbjct: 248 GMTVKHCALSLVGEPIMYPEINRFLKLLHQCKISSFLVTNAQFPAEIRNLEPVTQLYVSV 307

Query: 470 DASTKDSLKKIDRPLFKDFWQQFLDSLKALAVKQQRTVYRLTLVKAWNVDELQAYAQLVS 529
           DASTKDSLKKIDRPLFKDFWQQFLDSLKALAVKQQRTVYRLTLVKAWNVDELQAYAQLVS
Sbjct: 308 DASTKDSLKKIDRPLFKDFWQQFLDSLKALAVKQQRTVYRLTLVKAWNVDELQAYAQLVS 367

Query: 530 LGNPDFIEVKGVTYCRESSASSLTMAHVPWHEEVVQFVRELVDLIPEYEIACEHEHSNCL 589
           LGNPDFIEVKGVTYCRESSASSLTMAHVPWHEEVVQFVRELVDLIPEYEIACEHEHSNCL
Sbjct: 368 LGNPDFIEVKGVTYCRESSASSLTMAHVPWHEEVVQFVRELVDLIPEYEIACEHEHSNCL 427

Query: 590 LIAHRKFKIGG---------EWWTWI 606
           LIAHRK  +GG         +W  WI
Sbjct: 428 LIAHRKTVLGGTPGHGVTEIQWEEWI 453



 Score =  162 bits (409), Expect = 1e-39
 Identities = 79/79 (100%), Positives = 79/79 (100%)

Query: 1  MDPSADTWDLSSPLISLWINRFYIYLGFAVSISLWICVQIVIEMQGFATVLAEAVTSLDL 60
          MDPSADTWDLSSPLISLWINRFYIYLGFAVSISLWICVQIVIEMQGFATVLAEAVTSLDL
Sbjct: 1  MDPSADTWDLSSPLISLWINRFYIYLGFAVSISLWICVQIVIEMQGFATVLAEAVTSLDL 60

Query: 61 PVAIINLKEYDPDDHLIEE 79
          PVAIINLKEYDPDDHLIEE
Sbjct: 61 PVAIINLKEYDPDDHLIEE 79


>gi|127139033 cytochrome P450 reductase [Homo sapiens]
          Length = 680

 Score = 82.8 bits (203), Expect = 9e-16
 Identities = 48/125 (38%), Positives = 72/125 (57%), Gaps = 19/125 (15%)

Query: 71  DPDDHLIEEVTS-----KNVCVFLVATYTDGLPTESAEWFCKWLEEASIDFRFGKTYLKG 125
           DP+++ + +++S       + VF +ATY +G PT++A+ F  WL+E  +D       L G
Sbjct: 116 DPEEYDLADLSSLPEIDNALVVFCMATYGEGDPTDNAQDFYDWLQETDVD-------LSG 168

Query: 126 MRDAVFGLGNSAYASHFNKVGKNVDKWLWMLGVHRVMSRGEGDCDVVKSKHGSIEANFRA 185
           ++ AVFGLGN  Y  HFN +GK VDK L  LG  R+   G GD D      G++E +F  
Sbjct: 169 VKFAVFGLGNKTY-EHFNAMGKYVDKRLEQLGAQRIFELGLGDDD------GNLEEDFIT 221

Query: 186 WKTKF 190
           W+ +F
Sbjct: 222 WREQF 226


>gi|103471997 DNA-directed RNA polymerase I A [Homo sapiens]
          Length = 1720

 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 48/168 (28%), Positives = 79/168 (47%), Gaps = 26/168 (15%)

Query: 172  VKSKHGSIEANFRAWKTKFISQLQALQKGERKKSCGGHCKKGKCESHQHGSE-EREEGSQ 230
            +K K+    A FR   T+  +Q      GE  +S G   ++G  E   H  + E EEG  
Sbjct: 1354 IKKKNNKASA-FRNVNTRRATQRDLDNAGELGRSRGE--QEGDEEEEGHIVDAEAEEGDA 1410

Query: 231  EQDELHHRDTKEEE-PFESSSEEEFGGEDHQSLNSIVDVEDLGKIMDHVKKEKREKEQQE 289
            +  +   ++ +EEE  +ES  EEE  GE++       D ED+ +  +  ++  R+ ++Q+
Sbjct: 1411 DASDAKRKEKQEEEVDYESEEEEEREGEEN-------DDEDMQEERNPHREGARKTQEQD 1463

Query: 290  EKSGLFRNMGRNEDGERRAMIT----------PALREALTKQVDAPRE 327
            E+ GL    G  ED    A++T          P   EA+ ++V A RE
Sbjct: 1464 EEVGL----GTEEDPSLPALLTQPRKPTHSQEPQGPEAMERRVQAVRE 1507


>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
           sapiens]
          Length = 1152

 Score = 43.5 bits (101), Expect = 6e-04
 Identities = 43/162 (26%), Positives = 64/162 (39%), Gaps = 26/162 (16%)

Query: 164 RGEGDCDVVKS--KHGSIEANFRAWKTKFISQLQALQKGER--------KKSCG------ 207
           RG+G C+   S  +H   E   +  K K   +++   +GE+        KK  G      
Sbjct: 654 RGDGTCEEGSSGAEHWQDEEREKGEKDKGRGEMERPGEGEKELAEKEEWKKRDGEEQEQK 713

Query: 208 ----GHCKKGKCESHQHGSEEREEGSQEQDELHHRDTKEEEPFESSSEEEFGGEDHQSLN 263
               GH K+   E  + G EE  EG +E+ +    + KE E  E    EE  GE  +   
Sbjct: 714 EREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEG 773

Query: 264 SIVDVEDLGKIMDHVKKEKREKEQQEEKSGLFRNMGRNEDGE 305
                E  G      K+EK E+E  + +       GR E+ E
Sbjct: 774 ERKKEERAG------KEEKGEEEGDQGEGEEEETEGRGEEKE 809



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 28/107 (26%), Positives = 51/107 (47%), Gaps = 5/107 (4%)

Query: 199 KGERKKSCGGHCKKGKCESHQHGSEEREEGSQEQDELHHRDTKEEEPFESSSEEEFGGED 258
           +GER+K  G   K+ +    + G EE ++G  E++E   R  ++EE       E  GGE 
Sbjct: 765 EGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEE-----GGEVEGGEV 819

Query: 259 HQSLNSIVDVEDLGKIMDHVKKEKREKEQQEEKSGLFRNMGRNEDGE 305
            +      + E+ G+  +   + + E+ + EE+ G  +     E+GE
Sbjct: 820 EEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGE 866



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 31/100 (31%), Positives = 46/100 (46%), Gaps = 10/100 (10%)

Query: 208  GHCKKGKCESHQHGSEEREEGSQEQDELHHRDTKEEEPFESSSEEEFGGEDHQSLNSIVD 267
            G  ++G+ E  + G  E EEG  E +E       EEE  E   EEE  GE  +      +
Sbjct: 957  GEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEE--GEGEEEGEGEGE 1014

Query: 268  VEDLGKIMDHVKKEKREKEQQEEKSGLFRNMGRNEDGERR 307
             E+ G++   V+ E+ E E +EE+          E+GE R
Sbjct: 1015 EEEEGEVEGEVEGEEGEGEGEEEEG--------EEEGEER 1046



 Score = 37.4 bits (85), Expect = 0.045
 Identities = 35/119 (29%), Positives = 53/119 (44%), Gaps = 16/119 (13%)

Query: 199 KGERKKSCG----GHCKKGKCESHQ-----HGSEEREEGSQEQDELHHRDTK---EEEPF 246
           +GE K+  G    G  ++GK E  +      G EE  EG +E+ E    + +   EEE  
Sbjct: 804 RGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGE 863

Query: 247 ESSSEEEFGGEDHQSLNSIVDVEDLGKIMDHVKKEKREKEQQEEKSGLFRNMGRNEDGE 305
           E   EEE  GE+ +      + E  G+     + E+ E E + E+ G     G  E+GE
Sbjct: 864 EGEGEEE--GEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEG--EGEGEEEEGE 918



 Score = 36.6 bits (83), Expect = 0.077
 Identities = 32/108 (29%), Positives = 48/108 (44%), Gaps = 5/108 (4%)

Query: 198  QKGERKKSCGGHCKKGKCESHQHGSEEREEGSQEQDELHHRDTKEEEPFESSSEEEFGGE 257
            ++GE K    G   +G+ E  + G  E E+G  E +E       EEE  E   EEE  GE
Sbjct: 915  EEGEGKGEEEGEEGEGEGEEEE-GEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGE 973

Query: 258  DHQSLNSIVDVEDLGKIMDHVKKEKREKEQQEEKSGLFRNMGRNEDGE 305
              +      + E  G+     ++E+ E+E +EE  G     G  E+ E
Sbjct: 974  GEEGEGEGEEEEGEGE----GEEEEGEEEGEEEGEGEEEGEGEGEEEE 1017



 Score = 35.4 bits (80), Expect = 0.17
 Identities = 32/117 (27%), Positives = 56/117 (47%), Gaps = 14/117 (11%)

Query: 199  KGERKKSCG-GHCKKGKCESHQHGSEER--EEGSQEQDELHHRDTKEEEPFESSSEEEFG 255
            +GE ++  G G  ++G+ E  +   EE   EEG  E++     + +EE   E   E E G
Sbjct: 971  EGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEG 1030

Query: 256  ---GEDHQSLNSIVDVEDLGKIMDHVKKEKREKEQQEEKSGLFRNMGRNE----DGE 305
               GE+ +      + E  G+     ++ +R +E++EE+ G ++  G  E    DGE
Sbjct: 1031 EGEGEEEEGEEEGEEREKEGE----GEENRRNREEEEEEEGKYQETGEEENERQDGE 1083



 Score = 34.7 bits (78), Expect = 0.29
 Identities = 32/112 (28%), Positives = 50/112 (44%), Gaps = 8/112 (7%)

Query: 198 QKGERKKSCG-GHCKKGKCESHQ---HGSEEREEGSQEQDELHHRDTKEEEPFESSSEEE 253
           ++GE ++  G G  ++G+ E  +    G EE EEG  E++        EEE  E   EEE
Sbjct: 831 EEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEE 890

Query: 254 FGGEDHQSLNSIVDVEDLGKIMDHVKKEKREKEQQEEKSGLFRNMGRNEDGE 305
             GE  +        E+     +  + E + +E+ EE  G     G  E+GE
Sbjct: 891 GEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEG----EGEEEEGE 938



 Score = 34.7 bits (78), Expect = 0.29
 Identities = 30/108 (27%), Positives = 49/108 (45%), Gaps = 2/108 (1%)

Query: 199  KGERKKSCGGHCKKGKCESHQ-HGSEEREEGSQEQDELHHRDTKEEEPFESSSEEEFGGE 257
            +GE ++  G   ++G+ E  +  G  E EEG  E +E    +  EEE  E   E E  GE
Sbjct: 956  EGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEG-EGEEEGEGEGE 1014

Query: 258  DHQSLNSIVDVEDLGKIMDHVKKEKREKEQQEEKSGLFRNMGRNEDGE 305
            + +      +VE      +  ++E  E+ ++ EK G      RN + E
Sbjct: 1015 EEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEE 1062



 Score = 33.9 bits (76), Expect = 0.50
 Identities = 25/92 (27%), Positives = 46/92 (50%), Gaps = 2/92 (2%)

Query: 198  QKGERKKSCGGHCKKGKCESHQHGSEEREEGSQEQDELHHRDTKEEEPFESSSEEEFGGE 257
            ++GE +    G   +G+ E  + G EE EE  +E +   +R  +EEE  E    +E G E
Sbjct: 1017 EEGEVEGEVEGEEGEGEGEEEE-GEEEGEEREKEGEGEENRRNREEEEEEEGKYQETGEE 1075

Query: 258  DHQSLNSIVDVEDLGKIMDHVKKEKREKEQQE 289
            +++  +   + + + KI   VK  K +  Q++
Sbjct: 1076 ENERQDG-EEYKKVSKIKGSVKYGKHKTYQKK 1106



 Score = 30.8 bits (68), Expect = 4.2
 Identities = 31/109 (28%), Positives = 48/109 (44%), Gaps = 8/109 (7%)

Query: 199 KGERKKSCGGHCKKGKCESHQHGSEEREEGSQEQDELHHRDTKEEEPFESSSEEEFG-GE 257
           +GE ++  G    +G+ E    G EE  EG  E++        EEE  E   E+  G GE
Sbjct: 894 EGEEEEGEG----EGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGE 949

Query: 258 DHQSLNSIVDVEDLGKIMDHVKKEKREKE-QQEEKSGLFRNMGRNEDGE 305
           + +      + E  G+  +  + E  E E + EE+ G     G  E+GE
Sbjct: 950 EEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEG--EGEGEEEEGE 996



 Score = 30.8 bits (68), Expect = 4.2
 Identities = 22/83 (26%), Positives = 36/83 (43%), Gaps = 3/83 (3%)

Query: 212  KGKCESHQHGSEERE---EGSQEQDELHHRDTKEEEPFESSSEEEFGGEDHQSLNSIVDV 268
            +G+ E    G EE E   EG  E +E      +EE   E    E+ G  +    N   + 
Sbjct: 1004 EGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEE 1063

Query: 269  EDLGKIMDHVKKEKREKEQQEEK 291
            E+ GK  +  ++E   ++ +E K
Sbjct: 1064 EEEGKYQETGEEENERQDGEEYK 1086



 Score = 30.0 bits (66), Expect = 7.2
 Identities = 33/117 (28%), Positives = 48/117 (41%), Gaps = 15/117 (12%)

Query: 199  KGERKKSCG---GHCKKGKCESHQ-HGSEEREEGSQEQDELHHRDTKEEE------PFES 248
            KGE +   G   G  ++G+ E     G  E EEG  E +E       EEE        E 
Sbjct: 920  KGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEG 979

Query: 249  SSEEEFGGEDHQSLNSIVDVEDLGKIMDHVKKEKREKEQQEEKSGLFRNMGRNEDGE 305
              EEE G  + +      + E+ G+      +E+ E E +EE+ G        E+GE
Sbjct: 980  EGEEEEGEGEGEEEEGEEEGEEEGE-----GEEEGEGEGEEEEEGEVEGEVEGEEGE 1031


>gi|155030232 proline, glutamic acid and leucine rich protein 1 [Homo
            sapiens]
          Length = 1130

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 36/144 (25%), Positives = 59/144 (40%), Gaps = 15/144 (10%)

Query: 216  ESHQHGSEEREEGSQEQDELHHRDTKEEEPFESSSEEEFGGEDHQSLNSIVDVEDLGKIM 275
            E  +   EE EE  +E+++    +  EEE FE   EEE   E+          E+ G++ 
Sbjct: 891  EEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFE-------EEEGELE 943

Query: 276  DHVKKEKREKEQQEEKSGLFRNMGRNEDGERRAMITPALREALTKQVDAPRERS------ 329
            +  ++E  E+E++ E+           + E  A   P L  AL      P+ +       
Sbjct: 944  EEEEEEDEEEEEELEEVEDLEFGTAGGEVEEGAPPPPTLPPALPPPESPPKVQPEPEPEP 1003

Query: 330  --LLQTHILWNESHRCMETTPSLA 351
              LL+      E  R  +T P+LA
Sbjct: 1004 GLLLEVEEPGTEEERGADTAPTLA 1027


>gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]
          Length = 770

 Score = 40.0 bits (92), Expect = 0.007
 Identities = 35/145 (24%), Positives = 59/145 (40%), Gaps = 10/145 (6%)

Query: 191 ISQLQALQKGERKKSCGGHCKKGKCESHQHGS----EEREEGSQEQDELHHRDTKEEEPF 246
           +S LQ +   ERK S        +  S + GS    EE EE  +E++     +++EEE  
Sbjct: 251 LSDLQDISDSERKTS------SAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEE 304

Query: 247 ESSSEEEFGGEDHQSLNSIVDVEDLGKIMDHVKKEKREKEQQEEKSGLFRNMGRNEDGER 306
           E   EEE G    ++     +     ++ +  ++E         +S   R+ G +E+ E 
Sbjct: 305 EEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEE 364

Query: 307 RAMITPALREALTKQVDAPRERSLL 331
                     ALT+    P   +LL
Sbjct: 365 EVGEGTPQSSALTEGDYVPDSPALL 389



 Score = 30.8 bits (68), Expect = 4.2
 Identities = 20/71 (28%), Positives = 37/71 (52%), Gaps = 3/71 (4%)

Query: 223 EEREEGSQEQDELHHRDTKEEEPFESSSEEEFGGEDHQSLNSIVDVEDLGKIMDHVKKEK 282
           EER+  S  QD +   + K      SS+E   G E+ +      + E+ G   +  ++E+
Sbjct: 246 EERDLLSDLQD-ISDSERKTSSAESSSAESGSGSEEEEEEEE--EEEEEGSTSEESEEEE 302

Query: 283 REKEQQEEKSG 293
            E+E++EE++G
Sbjct: 303 EEEEEEEEETG 313


>gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]
          Length = 780

 Score = 40.0 bits (92), Expect = 0.007
 Identities = 35/145 (24%), Positives = 59/145 (40%), Gaps = 10/145 (6%)

Query: 191 ISQLQALQKGERKKSCGGHCKKGKCESHQHGS----EEREEGSQEQDELHHRDTKEEEPF 246
           +S LQ +   ERK S        +  S + GS    EE EE  +E++     +++EEE  
Sbjct: 261 LSDLQDISDSERKTS------SAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEE 314

Query: 247 ESSSEEEFGGEDHQSLNSIVDVEDLGKIMDHVKKEKREKEQQEEKSGLFRNMGRNEDGER 306
           E   EEE G    ++     +     ++ +  ++E         +S   R+ G +E+ E 
Sbjct: 315 EEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEE 374

Query: 307 RAMITPALREALTKQVDAPRERSLL 331
                     ALT+    P   +LL
Sbjct: 375 EVGEGTPQSSALTEGDYVPDSPALL 399



 Score = 31.2 bits (69), Expect = 3.2
 Identities = 26/119 (21%), Positives = 45/119 (37%), Gaps = 13/119 (10%)

Query: 211 KKGKCESHQHGSEEREEGSQEQDELHHRDTKEEEPFESSSEEEFGGEDHQSLNSIVDVED 270
           +K KC  H H +E  +    ++ E   R    EE  +  +  E+  +  + +        
Sbjct: 105 RKEKCRHHSHSAEGGKHARVKEREHERRKRHREE--QDKARREWERQKRREM-------- 154

Query: 271 LGKIMDHVKKEKREKEQQEEKSGLFRNMGRNEDGERRAMITPALREALTKQVDAPRERS 329
                +H ++E+   EQ E K    R M   +  +R         E   K+ +A RE S
Sbjct: 155 ---AREHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVS 210



 Score = 30.8 bits (68), Expect = 4.2
 Identities = 20/71 (28%), Positives = 37/71 (52%), Gaps = 3/71 (4%)

Query: 223 EEREEGSQEQDELHHRDTKEEEPFESSSEEEFGGEDHQSLNSIVDVEDLGKIMDHVKKEK 282
           EER+  S  QD +   + K      SS+E   G E+ +      + E+ G   +  ++E+
Sbjct: 256 EERDLLSDLQD-ISDSERKTSSAESSSAESGSGSEEEEEEEE--EEEEEGSTSEESEEEE 312

Query: 283 REKEQQEEKSG 293
            E+E++EE++G
Sbjct: 313 EEEEEEEEETG 323


>gi|83716024 kinesin family member 21B [Homo sapiens]
          Length = 1624

 Score = 40.0 bits (92), Expect = 0.007
 Identities = 36/138 (26%), Positives = 61/138 (44%), Gaps = 22/138 (15%)

Query: 191 ISQLQALQKGERKKSCGGHCKKGKCESHQHGSEEREEGSQEQDE-------LHHRDTKEE 243
           + +L+  +  +R+KS      K + +  Q  SEE +E   E++E           + +E+
Sbjct: 548 LERLKKKEVRQRRKSPEKEAFKKRAKLQQENSEETDENEAEEEEEERDESGCEEEEGRED 607

Query: 244 EPFESSSEEEFGGED----HQSLNSIVDVEDL-------GKIMDHVKKEKRE----KEQQ 288
           E  +S SEE     D     + +N   D+ DL        K++D ++  +R     K Q 
Sbjct: 608 EDEDSGSEESLVDSDSDPEEKEVNFQADLADLTCEIEIKQKLIDELENSQRRLQTLKHQY 667

Query: 289 EEKSGLFRNMGRNEDGER 306
           EEK  L +N  R+   ER
Sbjct: 668 EEKLILLQNKIRDTQLER 685


>gi|10835173 nitric oxide synthase 1, neuronal [Homo sapiens]
          Length = 1434

 Score = 38.9 bits (89), Expect = 0.015
 Identities = 49/200 (24%), Positives = 78/200 (39%), Gaps = 42/200 (21%)

Query: 123  LKGMRDAVFGLGNSAYASHFNKVGKNVDKWLWMLGVHRVMSRGEGD-------------- 168
            L  +R +VFGLG+ AY  HF   G  VD  L  LG  R++   EGD              
Sbjct: 879  LANVRFSVFGLGSRAYP-HFCAFGHAVDTLLEELGGERILKMREGDELCGQEEAFRTWAK 937

Query: 169  ------CDV--------VKSKHGSIEANFRAWKTK-----FISQLQALQKG---ERKKSC 206
                  CDV        ++  + S+ +N R+WK       F+++   L +G     KK  
Sbjct: 938  KVFKAACDVFCVGDDVNIEKANNSLISNDRSWKRNKFRLTFVAEAPELTQGLSNVHKK-- 995

Query: 207  GGHCKKGKCESHQHGSEEREEGSQEQDELHHRDTKEEEPFESSSEEEFGGEDHQSLNSIV 266
                   +  S Q+    +   S     LH   ++E +         F G     +N+++
Sbjct: 996  --RVSAARLLSRQNLQSPKSSRSTIFVRLHTNGSQELQYQPGDHLGVFPGNHEDLVNALI 1053

Query: 267  D-VEDLGKIMDHVKKEKREK 285
            + +ED   +   VK E  E+
Sbjct: 1054 ERLEDAPPVNQMVKVELLEE 1073


>gi|148746195 trichohyalin [Homo sapiens]
          Length = 1943

 Score = 38.9 bits (89), Expect = 0.015
 Identities = 23/99 (23%), Positives = 54/99 (54%), Gaps = 5/99 (5%)

Query: 211 KKGKCESHQHGSEEREEGSQEQDELHHRDTKEEEPFESSSEEEFGGEDHQSLNSIVDVED 270
           +KG+ E  Q   E ++   QE++E   ++ ++ E      EE+   E+ Q    + + E+
Sbjct: 220 RKGREEKQQQRRERQDRVFQEEEE---KEWRKRETVLRKEEEKLQEEEPQRQRELQEEEE 276

Query: 271 LGKIMDH--VKKEKREKEQQEEKSGLFRNMGRNEDGERR 307
             + ++   +++E++E+EQQ+++    + + R ++ ERR
Sbjct: 277 QLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERR 315



 Score = 33.9 bits (76), Expect = 0.50
 Identities = 42/203 (20%), Positives = 81/203 (39%), Gaps = 20/203 (9%)

Query: 151  KWLWMLGVHRVMSRGEGDCDVVKSKHGSIEANFRAWKTKFISQLQALQKGERKKSCGGHC 210
            KW W L   R   R       + +K  +++   R  +     + + LQ+ ER+K      
Sbjct: 873  KWRWQLEEERKRRR-----HTLYAKP-ALQEQLRKEQQLLQEEEEELQREEREKRRRQEQ 926

Query: 211  KKGKCESHQHGSEE----REEGSQEQDELHHRDTKEEEPFESSSEEEFGGEDHQSLNS-- 264
            ++   E  Q   EE    REE  + + +   R  ++++  +   E+  G E  +      
Sbjct: 927  ERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQER 986

Query: 265  ---IVDVEDLGKIMDHVKKEKREKEQQEEKSGLFRNMGRNEDGERRAMITPALREALTKQ 321
                 + E+L +  + + +E+REK +++E    +R     +  E +      LRE   K+
Sbjct: 987  EKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQ-----LLREEREKR 1041

Query: 322  VDAPRERSLLQTHILWNESHRCM 344
                RER   +   L  E  + +
Sbjct: 1042 RLQERERQYREEEELQQEEEQLL 1064



 Score = 32.7 bits (73), Expect = 1.1
 Identities = 34/139 (24%), Positives = 60/139 (43%), Gaps = 14/139 (10%)

Query: 208 GHCKKGKCESHQHGSEEREEGSQEQDELHHRDT--KEEEPFESSSE----EEFGGEDHQ- 260
           G  ++ K +  +    E EE S++Q+ L  RD   ++EE +    E    EE   E+ Q 
Sbjct: 134 GQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQL 193

Query: 261 ------SLNSIVDVEDLGKI-MDHVKKEKREKEQQEEKSGLFRNMGRNEDGERRAMITPA 313
                       D E L +  +  ++++ RE++QQ+ +    R     E+ E R   T  
Sbjct: 194 QSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVL 253

Query: 314 LREALTKQVDAPRERSLLQ 332
            +E    Q + P+ +  LQ
Sbjct: 254 RKEEEKLQEEEPQRQRELQ 272



 Score = 31.6 bits (70), Expect = 2.5
 Identities = 29/129 (22%), Positives = 53/129 (41%), Gaps = 6/129 (4%)

Query: 223 EEREEGSQEQDELHHRDTKEEEPFESSSEEEFGGEDH------QSLNSIVDVEDLGKIMD 276
           EER E   EQ+    R  +E+E      + E   E H      Q L    + E   + + 
Sbjct: 431 EERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLK 490

Query: 277 HVKKEKREKEQQEEKSGLFRNMGRNEDGERRAMITPALREALTKQVDAPRERSLLQTHIL 336
             ++E+RE++++ E+        R E   +R      L++ L  +    RE+   +  +L
Sbjct: 491 LEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLL 550

Query: 337 WNESHRCME 345
             E  + +E
Sbjct: 551 KREEEKRLE 559



 Score = 31.2 bits (69), Expect = 3.2
 Identities = 26/108 (24%), Positives = 44/108 (40%), Gaps = 1/108 (0%)

Query: 189  KFISQLQALQKGERKKSCGGHCKKGKCESHQHGSEEREEGSQEQDELHHRDTKEEEPFES 248
            KF+ + Q L++ ER +      +  K    +   +EREE    + E   +   EE+    
Sbjct: 1532 KFLQEEQQLRRQERGQQ-RRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRR 1590

Query: 249  SSEEEFGGEDHQSLNSIVDVEDLGKIMDHVKKEKREKEQQEEKSGLFR 296
              +E    ED Q L      + L +  D   +E  +  Q+ E+  L R
Sbjct: 1591 QEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHR 1638



 Score = 30.4 bits (67), Expect = 5.5
 Identities = 25/106 (23%), Positives = 51/106 (48%), Gaps = 13/106 (12%)

Query: 224 EREEGSQ-EQDELHHRDTKEEEPFESSSEEEFGGEDHQSLNSIVDVEDLGKIMDHVKKEK 282
           +REE  + EQ+E   +  K EEP E   ++    E+ +        + L +     ++++
Sbjct: 603 KREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQ----QQLRREQQERREQR 658

Query: 283 REKEQQEEKSGLFRNMGRNEDGERRAMITPALREALTKQVDAPRER 328
            ++E++EE+  L + + R  + ERR       +E   ++ +  RER
Sbjct: 659 LKREEEEER--LEQRLKREHEEERRE------QELAEEEQEQARER 696



 Score = 29.6 bits (65), Expect = 9.4
 Identities = 26/119 (21%), Positives = 51/119 (42%), Gaps = 12/119 (10%)

Query: 224 EREEGSQEQDELHHRDT---KEEEPFESSSEEEFGGEDHQSLNSIVDVEDLGKIMDHVKK 280
           ER+E  Q+Q  L        K+EE      EE    ++ +        + L +  +  ++
Sbjct: 289 ERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERRE 348

Query: 281 EKREKEQQEEKSGLFRNMGRNEDGERRAMITPALREALTKQVDAPRERSLLQTHILWNE 339
           ++  +EQ+EE+    + + R ++ ERR        + L ++    RE+ L +   L  E
Sbjct: 349 QQLRREQEEERRE--QQLRREQEEERR-------EQQLRREQQLRREQQLRREQQLRRE 398



 Score = 29.6 bits (65), Expect = 9.4
 Identities = 26/117 (22%), Positives = 46/117 (39%)

Query: 223 EEREEGSQEQDELHHRDTKEEEPFESSSEEEFGGEDHQSLNSIVDVEDLGKIMDHVKKEK 282
           EER E  +E+ E   R  ++EE  E     E      Q L    + E   + +   ++E+
Sbjct: 312 EERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEE 371

Query: 283 REKEQQEEKSGLFRNMGRNEDGERRAMITPALREALTKQVDAPRERSLLQTHILWNE 339
           R ++Q   +  L R      + + R        + L ++    RE+ L +   L  E
Sbjct: 372 RREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRRE 428


>gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           9 [Homo sapiens]
          Length = 771

 Score = 38.5 bits (88), Expect = 0.020
 Identities = 32/134 (23%), Positives = 55/134 (41%), Gaps = 10/134 (7%)

Query: 191 ISQLQALQKGERKKSCGGHCKKGKCESHQHGS----EEREEGSQEQDELHHRDTKEEEPF 246
           +S LQ +   ERK S        +  S + GS    EE EE  +E++     +++EEE  
Sbjct: 252 LSDLQDISDSERKTS------SAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEE 305

Query: 247 ESSSEEEFGGEDHQSLNSIVDVEDLGKIMDHVKKEKREKEQQEEKSGLFRNMGRNEDGER 306
           E   EEE G    ++     +     ++ +  ++E         +S   R+ G +E+ E 
Sbjct: 306 EEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEE 365

Query: 307 RAMITPALREALTK 320
                     ALT+
Sbjct: 366 EVGEGTPQSSALTE 379



 Score = 30.8 bits (68), Expect = 4.2
 Identities = 20/71 (28%), Positives = 37/71 (52%), Gaps = 3/71 (4%)

Query: 223 EEREEGSQEQDELHHRDTKEEEPFESSSEEEFGGEDHQSLNSIVDVEDLGKIMDHVKKEK 282
           EER+  S  QD +   + K      SS+E   G E+ +      + E+ G   +  ++E+
Sbjct: 247 EERDLLSDLQD-ISDSERKTSSAESSSAESGSGSEEEEEEEE--EEEEEGSTSEESEEEE 303

Query: 283 REKEQQEEKSG 293
            E+E++EE++G
Sbjct: 304 EEEEEEEEETG 314


>gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           8 [Homo sapiens]
          Length = 780

 Score = 38.5 bits (88), Expect = 0.020
 Identities = 32/134 (23%), Positives = 55/134 (41%), Gaps = 10/134 (7%)

Query: 191 ISQLQALQKGERKKSCGGHCKKGKCESHQHGS----EEREEGSQEQDELHHRDTKEEEPF 246
           +S LQ +   ERK S        +  S + GS    EE EE  +E++     +++EEE  
Sbjct: 261 LSDLQDISDSERKTS------SAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEE 314

Query: 247 ESSSEEEFGGEDHQSLNSIVDVEDLGKIMDHVKKEKREKEQQEEKSGLFRNMGRNEDGER 306
           E   EEE G    ++     +     ++ +  ++E         +S   R+ G +E+ E 
Sbjct: 315 EEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEE 374

Query: 307 RAMITPALREALTK 320
                     ALT+
Sbjct: 375 EVGEGTPQSSALTE 388



 Score = 30.8 bits (68), Expect = 4.2
 Identities = 20/71 (28%), Positives = 37/71 (52%), Gaps = 3/71 (4%)

Query: 223 EEREEGSQEQDELHHRDTKEEEPFESSSEEEFGGEDHQSLNSIVDVEDLGKIMDHVKKEK 282
           EER+  S  QD +   + K      SS+E   G E+ +      + E+ G   +  ++E+
Sbjct: 256 EERDLLSDLQD-ISDSERKTSSAESSSAESGSGSEEEEEEEE--EEEEEGSTSEESEEEE 312

Query: 283 REKEQQEEKSG 293
            E+E++EE++G
Sbjct: 313 EEEEEEEEETG 323


>gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           5 [Homo sapiens]
          Length = 748

 Score = 38.5 bits (88), Expect = 0.020
 Identities = 32/134 (23%), Positives = 55/134 (41%), Gaps = 10/134 (7%)

Query: 191 ISQLQALQKGERKKSCGGHCKKGKCESHQHGS----EEREEGSQEQDELHHRDTKEEEPF 246
           +S LQ +   ERK S        +  S + GS    EE EE  +E++     +++EEE  
Sbjct: 229 LSDLQDISDSERKTS------SAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEE 282

Query: 247 ESSSEEEFGGEDHQSLNSIVDVEDLGKIMDHVKKEKREKEQQEEKSGLFRNMGRNEDGER 306
           E   EEE G    ++     +     ++ +  ++E         +S   R+ G +E+ E 
Sbjct: 283 EEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEE 342

Query: 307 RAMITPALREALTK 320
                     ALT+
Sbjct: 343 EVGEGTPQSSALTE 356



 Score = 30.8 bits (68), Expect = 4.2
 Identities = 20/71 (28%), Positives = 37/71 (52%), Gaps = 3/71 (4%)

Query: 223 EEREEGSQEQDELHHRDTKEEEPFESSSEEEFGGEDHQSLNSIVDVEDLGKIMDHVKKEK 282
           EER+  S  QD +   + K      SS+E   G E+ +      + E+ G   +  ++E+
Sbjct: 224 EERDLLSDLQD-ISDSERKTSSAESSSAESGSGSEEEEEEEE--EEEEEGSTSEESEEEE 280

Query: 283 REKEQQEEKSG 293
            E+E++EE++G
Sbjct: 281 EEEEEEEEETG 291


>gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           4 [Homo sapiens]
          Length = 737

 Score = 38.5 bits (88), Expect = 0.020
 Identities = 32/134 (23%), Positives = 55/134 (41%), Gaps = 10/134 (7%)

Query: 191 ISQLQALQKGERKKSCGGHCKKGKCESHQHGS----EEREEGSQEQDELHHRDTKEEEPF 246
           +S LQ +   ERK S        +  S + GS    EE EE  +E++     +++EEE  
Sbjct: 218 LSDLQDISDSERKTS------SAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEE 271

Query: 247 ESSSEEEFGGEDHQSLNSIVDVEDLGKIMDHVKKEKREKEQQEEKSGLFRNMGRNEDGER 306
           E   EEE G    ++     +     ++ +  ++E         +S   R+ G +E+ E 
Sbjct: 272 EEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEE 331

Query: 307 RAMITPALREALTK 320
                     ALT+
Sbjct: 332 EVGEGTPQSSALTE 345



 Score = 30.8 bits (68), Expect = 4.2
 Identities = 20/71 (28%), Positives = 37/71 (52%), Gaps = 3/71 (4%)

Query: 223 EEREEGSQEQDELHHRDTKEEEPFESSSEEEFGGEDHQSLNSIVDVEDLGKIMDHVKKEK 282
           EER+  S  QD +   + K      SS+E   G E+ +      + E+ G   +  ++E+
Sbjct: 213 EERDLLSDLQD-ISDSERKTSSAESSSAESGSGSEEEEEEEE--EEEEEGSTSEESEEEE 269

Query: 283 REKEQQEEKSG 293
            E+E++EE++G
Sbjct: 270 EEEEEEEEETG 280


>gi|16332360 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           3 [Homo sapiens]
          Length = 526

 Score = 38.5 bits (88), Expect = 0.020
 Identities = 32/134 (23%), Positives = 55/134 (41%), Gaps = 10/134 (7%)

Query: 191 ISQLQALQKGERKKSCGGHCKKGKCESHQHGS----EEREEGSQEQDELHHRDTKEEEPF 246
           +S LQ +   ERK S        +  S + GS    EE EE  +E++     +++EEE  
Sbjct: 7   LSDLQDISDSERKTS------SAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEE 60

Query: 247 ESSSEEEFGGEDHQSLNSIVDVEDLGKIMDHVKKEKREKEQQEEKSGLFRNMGRNEDGER 306
           E   EEE G    ++     +     ++ +  ++E         +S   R+ G +E+ E 
Sbjct: 61  EEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEE 120

Query: 307 RAMITPALREALTK 320
                     ALT+
Sbjct: 121 EVGEGTPQSSALTE 134


>gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           2 [Homo sapiens]
          Length = 782

 Score = 38.5 bits (88), Expect = 0.020
 Identities = 32/134 (23%), Positives = 55/134 (41%), Gaps = 10/134 (7%)

Query: 191 ISQLQALQKGERKKSCGGHCKKGKCESHQHGS----EEREEGSQEQDELHHRDTKEEEPF 246
           +S LQ +   ERK S        +  S + GS    EE EE  +E++     +++EEE  
Sbjct: 263 LSDLQDISDSERKTS------SAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEE 316

Query: 247 ESSSEEEFGGEDHQSLNSIVDVEDLGKIMDHVKKEKREKEQQEEKSGLFRNMGRNEDGER 306
           E   EEE G    ++     +     ++ +  ++E         +S   R+ G +E+ E 
Sbjct: 317 EEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEE 376

Query: 307 RAMITPALREALTK 320
                     ALT+
Sbjct: 377 EVGEGTPQSSALTE 390



 Score = 30.8 bits (68), Expect = 4.2
 Identities = 20/71 (28%), Positives = 37/71 (52%), Gaps = 3/71 (4%)

Query: 223 EEREEGSQEQDELHHRDTKEEEPFESSSEEEFGGEDHQSLNSIVDVEDLGKIMDHVKKEK 282
           EER+  S  QD +   + K      SS+E   G E+ +      + E+ G   +  ++E+
Sbjct: 258 EERDLLSDLQD-ISDSERKTSSAESSSAESGSGSEEEEEEEE--EEEEEGSTSEESEEEE 314

Query: 283 REKEQQEEKSG 293
            E+E++EE++G
Sbjct: 315 EEEEEEEEETG 325


>gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]
          Length = 709

 Score = 38.5 bits (88), Expect = 0.020
 Identities = 23/90 (25%), Positives = 42/90 (46%)

Query: 201 ERKKSCGGHCKKGKCESHQHGSEEREEGSQEQDELHHRDTKEEEPFESSSEEEFGGEDHQ 260
           +R+ S      K +  S ++GS+     S   DE  +    EEE  E   EE+   E+  
Sbjct: 160 DRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDA 219

Query: 261 SLNSIVDVEDLGKIMDHVKKEKREKEQQEE 290
             +  VD +   +  +  ++E+ E+E++EE
Sbjct: 220 EEDEEVDEDGEEEEEEEEEEEEEEEEEEEE 249



 Score = 31.6 bits (70), Expect = 2.5
 Identities = 23/102 (22%), Positives = 42/102 (41%), Gaps = 12/102 (11%)

Query: 213 GKCESHQHGSEEREEGSQE---QDELHHRDTKEEEPFESSSEEEFGGEDHQSLNSIVDVE 269
           G  +   + +E  EEG +E   +DE    D +E+E  +   EEE   E+ +      + E
Sbjct: 189 GSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEE 248

Query: 270 DLGKIMDHVKKEKREKEQQEEKSGLFRNMGRNEDGERRAMIT 311
           +          E+ E++Q+EE +        ++ G      T
Sbjct: 249 EY---------EQDERDQKEEGNDYDTRSEASDSGSESVSFT 281


>gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]
          Length = 727

 Score = 38.5 bits (88), Expect = 0.020
 Identities = 23/90 (25%), Positives = 42/90 (46%)

Query: 201 ERKKSCGGHCKKGKCESHQHGSEEREEGSQEQDELHHRDTKEEEPFESSSEEEFGGEDHQ 260
           +R+ S      K +  S ++GS+     S   DE  +    EEE  E   EE+   E+  
Sbjct: 160 DRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDA 219

Query: 261 SLNSIVDVEDLGKIMDHVKKEKREKEQQEE 290
             +  VD +   +  +  ++E+ E+E++EE
Sbjct: 220 EEDEEVDEDGEEEEEEEEEEEEEEEEEEEE 249



 Score = 31.6 bits (70), Expect = 2.5
 Identities = 23/102 (22%), Positives = 42/102 (41%), Gaps = 12/102 (11%)

Query: 213 GKCESHQHGSEEREEGSQE---QDELHHRDTKEEEPFESSSEEEFGGEDHQSLNSIVDVE 269
           G  +   + +E  EEG +E   +DE    D +E+E  +   EEE   E+ +      + E
Sbjct: 189 GSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEE 248

Query: 270 DLGKIMDHVKKEKREKEQQEEKSGLFRNMGRNEDGERRAMIT 311
           +          E+ E++Q+EE +        ++ G      T
Sbjct: 249 EY---------EQDERDQKEEGNDYDTRSEASDSGSESVSFT 281


>gi|239756368 PREDICTED: similar to acidic (leucine-rich) nuclear
           phosphoprotein 32 family, member B [Homo sapiens]
          Length = 272

 Score = 38.1 bits (87), Expect = 0.026
 Identities = 26/83 (31%), Positives = 41/83 (49%), Gaps = 2/83 (2%)

Query: 223 EEREEGSQEQDELHHRDTKEEEPFESSSEEEFGGEDHQSLNSIVDVEDLGKIMDHVKKEK 282
           EE EEG  E+D  +    +EE   E   +E+  G+D +   S  + E+ G   D    E 
Sbjct: 189 EEDEEGEDEKDXENEDGEEEELDEEEDEDEDVEGDDDKDEVS-EEEEEFGLDKDE-DDED 246

Query: 283 REKEQQEEKSGLFRNMGRNEDGE 305
            +++++EE+SG   N  R  D E
Sbjct: 247 EDEDEEEEESGKGENRKRETDDE 269



 Score = 31.6 bits (70), Expect = 2.5
 Identities = 24/83 (28%), Positives = 40/83 (48%), Gaps = 11/83 (13%)

Query: 214 KCESHQHGSEEREEGSQEQDELHHRDTKEEEPFESSSEEEFG---GEDHQSLNSIVDVED 270
           K   ++ G EE  +  +++DE    D  ++E   S  EEEFG    ED +  +   + E+
Sbjct: 198 KDXENEDGEEEELDEEEDEDEDVEGDDDKDE--VSEEEEEFGLDKDEDDEDEDEDEEEEE 255

Query: 271 LGKIMDHVKKEKREKEQQEEKSG 293
            G      K E R++E  +E+ G
Sbjct: 256 SG------KGENRKRETDDEEDG 272


>gi|239750893 PREDICTED: similar to acidic (leucine-rich) nuclear
           phosphoprotein 32 family, member B [Homo sapiens]
          Length = 272

 Score = 38.1 bits (87), Expect = 0.026
 Identities = 26/83 (31%), Positives = 41/83 (49%), Gaps = 2/83 (2%)

Query: 223 EEREEGSQEQDELHHRDTKEEEPFESSSEEEFGGEDHQSLNSIVDVEDLGKIMDHVKKEK 282
           EE EEG  E+D  +    +EE   E   +E+  G+D +   S  + E+ G   D    E 
Sbjct: 189 EEDEEGEDEKDXENEDGEEEELDEEEDEDEDVEGDDDKDEVS-EEEEEFGLDKDE-DDED 246

Query: 283 REKEQQEEKSGLFRNMGRNEDGE 305
            +++++EE+SG   N  R  D E
Sbjct: 247 EDEDEEEEESGKGENRKRETDDE 269



 Score = 31.6 bits (70), Expect = 2.5
 Identities = 24/83 (28%), Positives = 40/83 (48%), Gaps = 11/83 (13%)

Query: 214 KCESHQHGSEEREEGSQEQDELHHRDTKEEEPFESSSEEEFG---GEDHQSLNSIVDVED 270
           K   ++ G EE  +  +++DE    D  ++E   S  EEEFG    ED +  +   + E+
Sbjct: 198 KDXENEDGEEEELDEEEDEDEDVEGDDDKDE--VSEEEEEFGLDKDEDDEDEDEDEEEEE 255

Query: 271 LGKIMDHVKKEKREKEQQEEKSG 293
            G      K E R++E  +E+ G
Sbjct: 256 SG------KGENRKRETDDEEDG 272


>gi|4759128 solute carrier family 24 (sodium/potassium/calcium
           exchanger), member 1 [Homo sapiens]
          Length = 1099

 Score = 38.1 bits (87), Expect = 0.026
 Identities = 26/71 (36%), Positives = 34/71 (47%), Gaps = 2/71 (2%)

Query: 193 QLQALQKGERKKSCGGHCKKGKCESHQHGSEEREEGSQEQDELHHRDTKEEEPFESSSEE 252
           +L A   GE K    G    G  +     SEE EE  +EQ+E    + +EEE  E   EE
Sbjct: 832 ELSAENHGEAKNDEKGVEDGGGSDGGD--SEEEEEEEEEQEEEEEEEEQEEEEEEEEEEE 889

Query: 253 EFGGEDHQSLN 263
           E G E+  SL+
Sbjct: 890 EKGNEEPLSLD 900



 Score = 33.5 bits (75), Expect = 0.65
 Identities = 28/108 (25%), Positives = 51/108 (47%), Gaps = 15/108 (13%)

Query: 199 KGERKKSCGGHCK---KGKCESHQHGSEEREEGSQE---------QDELHHRDTKEEEPF 246
           +GE ++  GG  +   +G+ E+   G E  +E   E         + E+H  D + +   
Sbjct: 766 EGETEEKSGGETQPEGEGETETQGKGEECEDENEAEGKGDNEGEDEGEIHAEDGEMKGNE 825

Query: 247 ESSSEEEFGGEDH-QSLNSIVDVEDLGKI--MDHVKKEKREKEQQEEK 291
             +  +E   E+H ++ N    VED G     D  ++E+ E+EQ+EE+
Sbjct: 826 GETESQELSAENHGEAKNDEKGVEDGGGSDGGDSEEEEEEEEEQEEEE 873


>gi|21735415 centromere protein B [Homo sapiens]
          Length = 599

 Score = 37.7 bits (86), Expect = 0.034
 Identities = 23/68 (33%), Positives = 34/68 (50%), Gaps = 1/68 (1%)

Query: 222 SEEREEGSQEQDELHHRDTKEEEPFESSSEEEFGGEDHQSLNSIVDVEDLGKIMDHVKKE 281
           SE  EE  +E++E       EEE  E   EEE GGE  + L    +VE+ G +    ++E
Sbjct: 403 SEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEG-EELGEEEEVEEEGDVDSDEEEE 461

Query: 282 KREKEQQE 289
           + E+   E
Sbjct: 462 EDEESSSE 469



 Score = 33.9 bits (76), Expect = 0.50
 Identities = 22/55 (40%), Positives = 29/55 (52%), Gaps = 3/55 (5%)

Query: 216 ESHQHGSEEREEGSQEQDELHHRDTKEEEPFESSSEEEFGGEDHQSLNSIVDVED 270
           E  + G EE EEG  E +EL   +  EEE    S EEE   ED +S +  ++ ED
Sbjct: 424 EEEEEGEEEEEEGG-EGEELGEEEEVEEEGDVDSDEEE--EEDEESSSEGLEAED 475



 Score = 32.0 bits (71), Expect = 1.9
 Identities = 17/68 (25%), Positives = 37/68 (54%), Gaps = 3/68 (4%)

Query: 225 REEGSQEQDELHHRDTKEEEPFESSSEEEFGGEDHQSLNSIVDVEDLGKIMDHVKKEKRE 284
           + EG +E++E    + +EEE  E   EEE G E+ +      ++ +  ++ +    +  E
Sbjct: 402 KSEGEEEEEE---EEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDE 458

Query: 285 KEQQEEKS 292
           +E+++E+S
Sbjct: 459 EEEEDEES 466


>gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo
           sapiens]
          Length = 2462

 Score = 37.7 bits (86), Expect = 0.034
 Identities = 39/152 (25%), Positives = 72/152 (47%), Gaps = 12/152 (7%)

Query: 198 QKGERKKSCGGHCKKGKCESHQHGSEEREEGSQEQDELHHRDTKEEEPFESSSEEEFGGE 257
           +K E  KS      + + +S Q   +++++  Q+Q +   R ++EE+  +   +E    E
Sbjct: 474 KKNENYKSLVRRSYRRRGKSQQQQQQQQQQQQQQQQQPMPRSSQEEKDEKEKEKEAEKEE 533

Query: 258 DHQSLNSIVDVEDLGKIMDHVKKEKREKEQQEEKSGLFRNMGR---NEDGERRAMITPAL 314
           +   + +  D EDL K     K +    E  +EK  +  + GR   N  G R+  IT ++
Sbjct: 534 EKPEVEN--DKEDLLK----EKTDDTSGEDNDEKEAV-ASKGRKTANSQGRRKGRITRSM 586

Query: 315 -REALTKQVDAPRERSLLQTHILWNESHRCME 345
             EA +++   P++ + L +  L NES R  E
Sbjct: 587 ANEANSEEAITPQQSAELASMEL-NESSRWTE 617


>gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo
           sapiens]
          Length = 2524

 Score = 37.7 bits (86), Expect = 0.034
 Identities = 39/152 (25%), Positives = 72/152 (47%), Gaps = 12/152 (7%)

Query: 198 QKGERKKSCGGHCKKGKCESHQHGSEEREEGSQEQDELHHRDTKEEEPFESSSEEEFGGE 257
           +K E  KS      + + +S Q   +++++  Q+Q +   R ++EE+  +   +E    E
Sbjct: 474 KKNENYKSLVRRSYRRRGKSQQQQQQQQQQQQQQQQQPMPRSSQEEKDEKEKEKEAEKEE 533

Query: 258 DHQSLNSIVDVEDLGKIMDHVKKEKREKEQQEEKSGLFRNMGR---NEDGERRAMITPAL 314
           +   + +  D EDL K     K +    E  +EK  +  + GR   N  G R+  IT ++
Sbjct: 534 EKPEVEN--DKEDLLK----EKTDDTSGEDNDEKEAV-ASKGRKTANSQGRRKGRITRSM 586

Query: 315 -REALTKQVDAPRERSLLQTHILWNESHRCME 345
             EA +++   P++ + L +  L NES R  E
Sbjct: 587 ANEANSEEAITPQQSAELASMEL-NESSRWTE 617


>gi|13569879 acidic (leucine-rich) nuclear phosphoprotein 32 family,
           member E isoform 1 [Homo sapiens]
          Length = 268

 Score = 37.7 bits (86), Expect = 0.034
 Identities = 28/88 (31%), Positives = 42/88 (47%), Gaps = 6/88 (6%)

Query: 223 EEREEGSQEQDELHHRDTKEEEPFESSSEEEFG-----GEDHQSLNSIVDVEDLGKIMDH 277
           EE E G  E  E    + +EE+  E   E+E G     GE+   L+ ++  E   +  D 
Sbjct: 174 EENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDD 233

Query: 278 VKKEKREKEQQEEKSGLFRNMGRNEDGE 305
              E+ E+E++EE+ GL R   R  D E
Sbjct: 234 DYVEEGEEEEEEEEGGL-RGEKRKRDAE 260


>gi|210147569 acidic (leucine-rich) nuclear phosphoprotein 32
           family, member E isoform 2 [Homo sapiens]
          Length = 227

 Score = 37.7 bits (86), Expect = 0.034
 Identities = 28/88 (31%), Positives = 42/88 (47%), Gaps = 6/88 (6%)

Query: 223 EEREEGSQEQDELHHRDTKEEEPFESSSEEEFG-----GEDHQSLNSIVDVEDLGKIMDH 277
           EE E G  E  E    + +EE+  E   E+E G     GE+   L+ ++  E   +  D 
Sbjct: 133 EENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDD 192

Query: 278 VKKEKREKEQQEEKSGLFRNMGRNEDGE 305
              E+ E+E++EE+ GL R   R  D E
Sbjct: 193 DYVEEGEEEEEEEEGGL-RGEKRKRDAE 219


>gi|210147571 acidic (leucine-rich) nuclear phosphoprotein 32
           family, member E isoform 3 [Homo sapiens]
          Length = 220

 Score = 37.7 bits (86), Expect = 0.034
 Identities = 28/88 (31%), Positives = 42/88 (47%), Gaps = 6/88 (6%)

Query: 223 EEREEGSQEQDELHHRDTKEEEPFESSSEEEFG-----GEDHQSLNSIVDVEDLGKIMDH 277
           EE E G  E  E    + +EE+  E   E+E G     GE+   L+ ++  E   +  D 
Sbjct: 126 EENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDD 185

Query: 278 VKKEKREKEQQEEKSGLFRNMGRNEDGE 305
              E+ E+E++EE+ GL R   R  D E
Sbjct: 186 DYVEEGEEEEEEEEGGL-RGEKRKRDAE 212


>gi|239050813 lipoxygenase homology domains 1 isoform 1 [Homo
           sapiens]
          Length = 2211

 Score = 37.4 bits (85), Expect = 0.045
 Identities = 25/78 (32%), Positives = 37/78 (47%), Gaps = 5/78 (6%)

Query: 185 AWKTKFISQLQALQKGERKKSCGGHCKKGKCESHQHGSEEREEGSQEQDELHHRDTKEEE 244
           A K K   +L+ L K ER K+     K  + +  + GS+E +EG +E+       + EEE
Sbjct: 914 ARKKKEKDKLRQLLKKERLKA-----KLQRKKKKRKGSDEEDEGEEEESSSSEESSSEEE 968

Query: 245 PFESSSEEEFGGEDHQSL 262
             E   EEE  G   Q +
Sbjct: 969 EMEEEEEEEEFGPGMQEV 986


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.133    0.414 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,027,690
Number of Sequences: 37866
Number of extensions: 1202181
Number of successful extensions: 7406
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 84
Number of HSP's successfully gapped in prelim test: 219
Number of HSP's that attempted gapping in prelim test: 5737
Number of HSP's gapped (non-prelim): 1115
length of query: 668
length of database: 18,247,518
effective HSP length: 109
effective length of query: 559
effective length of database: 14,120,124
effective search space: 7893149316
effective search space used: 7893149316
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.