Guide to the Human Genome
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Search of human proteins with 223972612

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|223972612 Crm, cramped-like [Homo sapiens]
         (1269 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|223972612 Crm, cramped-like [Homo sapiens]                        2551   0.0  
gi|163965366 nascent polypeptide-associated complex alpha subuni...    61   6e-09
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        56   2e-07
gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens]         55   3e-07
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ...    55   4e-07
gi|167736355 mucin 4 isoform a [Homo sapiens]                          53   2e-06
gi|91982772 mucin 17 [Homo sapiens]                                    50   1e-05
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    49   2e-05
gi|110832843 TBP-associated factor 4 [Homo sapiens]                    49   2e-05
gi|239508790 PREDICTED: hypothetical protein, partial [Homo sapi...    49   3e-05
gi|156616290 collagen type VI alpha 6 [Homo sapiens]                   48   5e-05
gi|112734870 hypothetical protein LOC57648 [Homo sapiens]              48   5e-05
gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Ho...    48   7e-05
gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Ho...    48   7e-05
gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Ho...    48   7e-05
gi|48762934 alpha 2 type I collagen [Homo sapiens]                     48   7e-05
gi|19920317 cytoskeleton-associated protein 4 [Homo sapiens]           47   9e-05
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]      47   9e-05
gi|41349484 proline-rich protein BstNI subfamily 1 isoform 2 pre...    47   9e-05
gi|236459851 ubinuclein 2 [Homo sapiens]                               47   1e-04
gi|58530876 melanoma antigen family C, 1 [Homo sapiens]                47   1e-04
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]     47   1e-04
gi|4507869 vasodilator-stimulated phosphoprotein [Homo sapiens]        47   2e-04
gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein ...    47   2e-04
gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein ...    47   2e-04
gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein ...    47   2e-04
gi|148612809 WNK lysine deficient protein kinase 1 [Homo sapiens]      46   2e-04
gi|239743232 PREDICTED: hypothetical protein XP_002342775 [Homo ...    46   2e-04
gi|29725624 collagen, type XXIII, alpha 1 [Homo sapiens]               46   2e-04
gi|41349486 proline-rich protein BstNI subfamily 1 isoform 3 pre...    46   2e-04

>gi|223972612 Crm, cramped-like [Homo sapiens]
          Length = 1269

 Score = 2551 bits (6613), Expect = 0.0
 Identities = 1269/1269 (100%), Positives = 1269/1269 (100%)

Query: 1    MTVKLGDGGSGEDGLKKLGKRAADEESLEGEGAGGADAAEESSGTKRDEKTPRAGADGPP 60
            MTVKLGDGGSGEDGLKKLGKRAADEESLEGEGAGGADAAEESSGTKRDEKTPRAGADGPP
Sbjct: 1    MTVKLGDGGSGEDGLKKLGKRAADEESLEGEGAGGADAAEESSGTKRDEKTPRAGADGPP 60

Query: 61   APPGAPQAPSPPQGSPQDQHHFLRSSVRPQSKRPRKDPPSAVGSGNAGGSGPRGKGAEGG 120
            APPGAPQAPSPPQGSPQDQHHFLRSSVRPQSKRPRKDPPSAVGSGNAGGSGPRGKGAEGG
Sbjct: 61   APPGAPQAPSPPQGSPQDQHHFLRSSVRPQSKRPRKDPPSAVGSGNAGGSGPRGKGAEGG 120

Query: 121  GSSSGNVSGVAPAAPAGGSRSSSRNLGSSGGEKEEGKKVRRQWESWSTEDKNTFFEGLYE 180
            GSSSGNVSGVAPAAPAGGSRSSSRNLGSSGGEKEEGKKVRRQWESWSTEDKNTFFEGLYE
Sbjct: 121  GSSSGNVSGVAPAAPAGGSRSSSRNLGSSGGEKEEGKKVRRQWESWSTEDKNTFFEGLYE 180

Query: 181  HGKDFEAIQNNIALKYKKKGKPASMVKNKEQVRHFYYRTWHKITKYIDFDHVFSRGLKKS 240
            HGKDFEAIQNNIALKYKKKGKPASMVKNKEQVRHFYYRTWHKITKYIDFDHVFSRGLKKS
Sbjct: 181  HGKDFEAIQNNIALKYKKKGKPASMVKNKEQVRHFYYRTWHKITKYIDFDHVFSRGLKKS 240

Query: 241  SQELYGLICYGELRKKIGGCMDDKNATKLNELIQVGATTVRYKGRNLRIKAPMCRALKKL 300
            SQELYGLICYGELRKKIGGCMDDKNATKLNELIQVGATTVRYKGRNLRIKAPMCRALKKL
Sbjct: 241  SQELYGLICYGELRKKIGGCMDDKNATKLNELIQVGATTVRYKGRNLRIKAPMCRALKKL 300

Query: 301  CDPDGLSDEEDQKPVRLPLKVPIELQPRNNHAWARVQSLAQNPRLRMIVELHRKVSSLIE 360
            CDPDGLSDEEDQKPVRLPLKVPIELQPRNNHAWARVQSLAQNPRLRMIVELHRKVSSLIE
Sbjct: 301  CDPDGLSDEEDQKPVRLPLKVPIELQPRNNHAWARVQSLAQNPRLRMIVELHRKVSSLIE 360

Query: 361  FLKQKWALHEVRVRKTLEERQLQDSCSAPMQEKVTLHLFPGENCTLTPLPGVARVVHSKA 420
            FLKQKWALHEVRVRKTLEERQLQDSCSAPMQEKVTLHLFPGENCTLTPLPGVARVVHSKA
Sbjct: 361  FLKQKWALHEVRVRKTLEERQLQDSCSAPMQEKVTLHLFPGENCTLTPLPGVARVVHSKA 420

Query: 421  FCTVHWQEGGRCKQSAKDAHVLPPAQILGIQSGQGTARGQVKCPRSGAEGKGVGRPPPAA 480
            FCTVHWQEGGRCKQSAKDAHVLPPAQILGIQSGQGTARGQVKCPRSGAEGKGVGRPPPAA
Sbjct: 421  FCTVHWQEGGRCKQSAKDAHVLPPAQILGIQSGQGTARGQVKCPRSGAEGKGVGRPPPAA 480

Query: 481  DALQSSGESSPESAPGEGAALSLSSPDAPDRPPPRHQDTGPCLEKTPAEGRDSPTREPGA 540
            DALQSSGESSPESAPGEGAALSLSSPDAPDRPPPRHQDTGPCLEKTPAEGRDSPTREPGA
Sbjct: 481  DALQSSGESSPESAPGEGAALSLSSPDAPDRPPPRHQDTGPCLEKTPAEGRDSPTREPGA 540

Query: 541  LPCACGQLPDLEDELSLLDPLPRYLKSCQDLIVPEQCRCADTRPGSEQPPLGGAASPEVL 600
            LPCACGQLPDLEDELSLLDPLPRYLKSCQDLIVPEQCRCADTRPGSEQPPLGGAASPEVL
Sbjct: 541  LPCACGQLPDLEDELSLLDPLPRYLKSCQDLIVPEQCRCADTRPGSEQPPLGGAASPEVL 600

Query: 601  APVSKEAADLAPTGPSPRPGPGLLLDVCTKDLADAPAEELQEKGSPAGPPPSQGQPAARP 660
            APVSKEAADLAPTGPSPRPGPGLLLDVCTKDLADAPAEELQEKGSPAGPPPSQGQPAARP
Sbjct: 601  APVSKEAADLAPTGPSPRPGPGLLLDVCTKDLADAPAEELQEKGSPAGPPPSQGQPAARP 660

Query: 661  PKEVPASRLAQQLREEGWNLQTSESLTLAEVYLMMGKPSKLQLEYDWLGPGRQDPRPGSL 720
            PKEVPASRLAQQLREEGWNLQTSESLTLAEVYLMMGKPSKLQLEYDWLGPGRQDPRPGSL
Sbjct: 661  PKEVPASRLAQQLREEGWNLQTSESLTLAEVYLMMGKPSKLQLEYDWLGPGRQDPRPGSL 720

Query: 721  PTALHKQRLLSCLLKLISTEVNPKLALEANTISTASVRPAQEEQSMTPPGKVVTVSSRSP 780
            PTALHKQRLLSCLLKLISTEVNPKLALEANTISTASVRPAQEEQSMTPPGKVVTVSSRSP
Sbjct: 721  PTALHKQRLLSCLLKLISTEVNPKLALEANTISTASVRPAQEEQSMTPPGKVVTVSSRSP 780

Query: 781  RCPRNQASLRSSKTFPPSSAPCSSGLRNPPRPLLVPGPSSTGSNDSDGGLFAVPTTLPPN 840
            RCPRNQASLRSSKTFPPSSAPCSSGLRNPPRPLLVPGPSSTGSNDSDGGLFAVPTTLPPN
Sbjct: 781  RCPRNQASLRSSKTFPPSSAPCSSGLRNPPRPLLVPGPSSTGSNDSDGGLFAVPTTLPPN 840

Query: 841  SRHGKLFSPSKEAELTFRQHLNSISMQSDFFLPKPRKLRNRHLRKPLVVQRTLLPRPSEN 900
            SRHGKLFSPSKEAELTFRQHLNSISMQSDFFLPKPRKLRNRHLRKPLVVQRTLLPRPSEN
Sbjct: 841  SRHGKLFSPSKEAELTFRQHLNSISMQSDFFLPKPRKLRNRHLRKPLVVQRTLLPRPSEN 900

Query: 901  QSHNVCSFSILSNSSVTGRGSFRPIQSSLTKAALSRPIVPKVLPPQATSHLASAIDLAAT 960
            QSHNVCSFSILSNSSVTGRGSFRPIQSSLTKAALSRPIVPKVLPPQATSHLASAIDLAAT
Sbjct: 901  QSHNVCSFSILSNSSVTGRGSFRPIQSSLTKAALSRPIVPKVLPPQATSHLASAIDLAAT 960

Query: 961  SAGILSGNPLPALDTEGLSGISPLSSDEVTGAISGQDSTGTHQDGDTLPTVGGSDPFVSI 1020
            SAGILSGNPLPALDTEGLSGISPLSSDEVTGAISGQDSTGTHQDGDTLPTVGGSDPFVSI
Sbjct: 961  SAGILSGNPLPALDTEGLSGISPLSSDEVTGAISGQDSTGTHQDGDTLPTVGGSDPFVSI 1020

Query: 1021 PSRPEQEPVADSFQGSSVLSLSELPKAPLQNGLSIPLSSSESSSTRLSPPDVSALLDISL 1080
            PSRPEQEPVADSFQGSSVLSLSELPKAPLQNGLSIPLSSSESSSTRLSPPDVSALLDISL
Sbjct: 1021 PSRPEQEPVADSFQGSSVLSLSELPKAPLQNGLSIPLSSSESSSTRLSPPDVSALLDISL 1080

Query: 1081 PGPPEDALSQGEPATHISDSIIEIAISSGQYGEGVPLSPAKLNGSDSSKSLPSPSSSPQP 1140
            PGPPEDALSQGEPATHISDSIIEIAISSGQYGEGVPLSPAKLNGSDSSKSLPSPSSSPQP
Sbjct: 1081 PGPPEDALSQGEPATHISDSIIEIAISSGQYGEGVPLSPAKLNGSDSSKSLPSPSSSPQP 1140

Query: 1141 HWIASPTHDPQWYPSDSTDSSLSSLFASFISPEKSRKMLPTPIGTNSGTSLLGPSLLDGN 1200
            HWIASPTHDPQWYPSDSTDSSLSSLFASFISPEKSRKMLPTPIGTNSGTSLLGPSLLDGN
Sbjct: 1141 HWIASPTHDPQWYPSDSTDSSLSSLFASFISPEKSRKMLPTPIGTNSGTSLLGPSLLDGN 1200

Query: 1201 SRDSFVSRSLADVAEVVDSQLVCMMNENSIDYISRFNDLAQELSIAEPGRREALFDGGGG 1260
            SRDSFVSRSLADVAEVVDSQLVCMMNENSIDYISRFNDLAQELSIAEPGRREALFDGGGG
Sbjct: 1201 SRDSFVSRSLADVAEVVDSQLVCMMNENSIDYISRFNDLAQELSIAEPGRREALFDGGGG 1260

Query: 1261 GPAVSDLSQ 1269
            GPAVSDLSQ
Sbjct: 1261 GPAVSDLSQ 1269


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 61.2 bits (147), Expect = 6e-09
 Identities = 171/780 (21%), Positives = 246/780 (31%), Gaps = 140/780 (17%)

Query: 435  SAKDAHVLP-PAQILGIQSGQGTARGQVKCPRSGAEGKGVGRP-----PPAADALQSSG- 487
            S K A   P P  I    S +G        P S   G     P     PPAA      G 
Sbjct: 917  SPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGG 976

Query: 488  --ESSPESAPGEGAALSLSSPDAPDRPPPRHQDTGPCLEKTPAEGRDSPTREPGALPCAC 545
                SP+ AP   AA   S    P  P P+   T P +     +G  + T  P       
Sbjct: 977  PATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPP 1036

Query: 546  GQLPDLEDELSLLDPLPRYLKSCQDLIVPE--------QCRCADTRPGSEQP-PLGGAAS 596
               P          PLP+   +     +P           + A T P +  P P GG A+
Sbjct: 1037 AATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPAT 1096

Query: 597  PEVLAPVSKEAADLAPTGPSPRPGPGLLLD----VCTKDLADAPAEE-----LQEKGSP- 646
            P      S + A + P    P P  GL         T   A  P+ +        KG+P 
Sbjct: 1097 P------SPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPT 1150

Query: 647  ---AGPPPSQGQPAARPPKEVPASRLAQQLREEGWNLQTSESLTLAEVYLMMGKPSKLQL 703
               A PP  +G  A  PPK  P +  A     +G     S            G P+    
Sbjct: 1151 TPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPK----------GAPTTPAA 1200

Query: 704  EYDWLGPGRQDPRPGSLPTALHKQRLLSCLLKLISTEVNPKLALEANTISTASVRPAQEE 763
                   G   P P   PT               +T  +PK       ++T S + A   
Sbjct: 1201 TPPSPKGGLATPSPKGAPTT------------PAATPPSPK-----GGLATPSPKGAPTT 1243

Query: 764  QSMTPPGKVVTVSSRSPRCPRNQASLRSSKTFPPSSAPCSSGLRNP-----PRPLLVPGP 818
             + TPP          P  P  + +       PPS      GL  P     P P +V  P
Sbjct: 1244 PAATPPS-----PKGGPATPPPKGAPTPPAATPPS---LKGGLATPPHKGAPNPAVVTPP 1295

Query: 819  SSTG--SNDSDGGLFAVPTTLPPNSRHGKLFSPSKEAELTFRQHLNSISMQSDFFLPKPR 876
            S  G  +     G    P   PP+ +      P K A                   P P+
Sbjct: 1296 SPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGA-----------PTPPAVTPPSPK 1344

Query: 877  KLRNRHLRKPLVVQRTLLPRPSENQSHNVCSFSILSNSSVTGRGSFRPIQSSLTKAALSR 936
                     P        P   E  +    + S     ++T     R       K   + 
Sbjct: 1345 GTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTS 1404

Query: 937  PIVPKVLPPQATSHLASAIDLAATSAGILSGNPLPALDTEGLSGISPLSSDE--VTGAIS 994
            P V  + P +A +   +    A  S G L+    PA        ++P+S  +   T A  
Sbjct: 1405 PAVIPLSPKKAPATPVTREGAATPSKGDLTP---PA--------VTPVSLKKAPATSAPK 1453

Query: 995  GQDSTGTHQDGDTLPTVGGSDP-------FVSIPSRPEQEPVADSFQGSSVL------SL 1041
            G  +T + +   TLP V    P        V+  S P++ P   +  G+  L      S 
Sbjct: 1454 GGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSP 1513

Query: 1042 SELPKAPLQNGLSIPLSS---SESSSTRLSPPDVSALLDISLPGP---PEDALSQGEPAT 1095
             E+P  P      I  ++   S+ +   L+P +      +++P P   P     +  PAT
Sbjct: 1514 KEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPAT 1573

Query: 1096 HISDSIIEIAISSGQYGEGVPLSPAKLNGSDSSKSL--------PSPSSSPQPHWIASPT 1147
                       SS +      ++P+   G+ S K L        PSP  +P P  +  P+
Sbjct: 1574 P----------SSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPS 1623



 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 179/774 (23%), Positives = 250/774 (32%), Gaps = 137/774 (17%)

Query: 428  EGGRCKQSAKDAHVLPPAQILGIQSGQGTARGQVKCPRSGAEGKGVGRPPPAADALQSSG 487
            +GG    S K A   P A     + G  T   +      GA       PP     L +  
Sbjct: 1183 KGGLATPSPKGAPTTPAATPPSPKGGLATPSPK------GAPTTPAATPPSPKGGLATP- 1235

Query: 488  ESSPESAPGEGAALSLSSPDAPDRPPPRHQDTGPCLEKTPAEGRDSPTREPGALPCACGQ 547
              SP+ AP   AA   S    P  PPP+   T P       +G  +     GA   A   
Sbjct: 1236 --SPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVT 1293

Query: 548  LPDLEDELSLLDPLPRYLKSCQDLIVPEQCRCADTRPGSEQPPLGGAASPEVLAPVSKEA 607
             P  +   +   P             P+        PG+  PP G    P V  P  K  
Sbjct: 1294 PPSPKGGPATSPPKGAPTPPAATPPSPK------GSPGT-PPPKGAPTPPAVTPPSPKGT 1346

Query: 608  ADLAPTGPSPRPGPGLLLDVCTKDLADAPAEELQEKGSPAGPPPSQGQ-PAARPPKEVPA 666
              L  T PS + GP       +K+    PA     KG PA  PPS  + PA   PK  P 
Sbjct: 1347 PTLPATTPSSKGGP---TTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPT 1403

Query: 667  SRL----------AQQLREEGWNLQTSESLTLAEVYLM-----------MGKPSKLQLEY 705
            S            A  +  EG    +   LT   V  +            G P+    + 
Sbjct: 1404 SPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKG 1463

Query: 706  DWLGPGRQDPRPGSLPTALHKQRLLSCLLKLISTEVNPKLALEANTISTASVRPAQEEQS 765
            D   P    P P   P             K ++T  +PK A        A   PA    S
Sbjct: 1464 DPTLPAVTPPSPKEPPAP-----------KQVATSSSPKKAPATPAPMGAPTLPAVIPSS 1512

Query: 766  MTPPGKVVTVSS-RSPRCPRNQASLRSSKTFPPSSAPCSSGLRNPPRPLLVPGPSSTGSN 824
              P     T SS R P  P   A+L S KT P + AP  + +   P  + VP P  T + 
Sbjct: 1513 --PKEVPATPSSRRDPIAP--TATLLSKKT-PATLAPKEALI---PPAMTVPSPKKTPA- 1563

Query: 825  DSDGGLFAVPTTLPPNSRHGKLFSPSKEAELTFRQHLNSISMQSDFFLPKPRKLRNRHLR 884
                     P   P      +  SP      T++              P P++L      
Sbjct: 1564 ------IPTPKEAPATPSSKEASSPPAVTPSTYKG------------APSPKEL------ 1599

Query: 885  KPLVVQRTLLPRPSENQSHNVCSFSILSNSSVTGRGSFRPIQSSLTKAALSRPIVPKVLP 944
              L+      P P E  +      ++   S   G     P   +      S P+ P  L 
Sbjct: 1600 --LIPPAVTSPSPKEAPTPP----AVTPPSPEKG-----PATPAPKGTPTSPPVTPSSLK 1648

Query: 945  PQATSHLASAIDLAATSAGILSGNPL---PALDTEGLSGISPLSSDEVTGAISGQDSTGT 1001
               TS  +    + AT      G P    P    E L   +P S+  +T     +    T
Sbjct: 1649 DSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPT--RKGPQT 1706

Query: 1002 HQDGDTLPTV--------GGSDPFVSI---PSRPEQEPVADSFQGSSVLSLSELPKAPLQ 1050
             +   T P +        G   P  ++   P  P Q+  + + +G       + P AP +
Sbjct: 1707 KKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPE 1766

Query: 1051 NGLSIPLSSS---------ESSSTRLSP-PDVSALLDIS-----------LPGPPEDAL- 1088
            +  S PL+++         ES+S   +P P VS  L  S           LP  P   L 
Sbjct: 1767 SKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLE 1826

Query: 1089 SQGEPATHISDSIIEIAISSGQYGEGVPLSPAKLN-GSDSSKSLPSPS-SSPQP 1140
            S  +P     +  +   I       GVP     +N  +  S  +P P+ S+ QP
Sbjct: 1827 SPSKPLAPADEDELLPLIPPEPISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQP 1880



 Score = 52.4 bits (124), Expect = 3e-06
 Identities = 168/739 (22%), Positives = 249/739 (33%), Gaps = 143/739 (19%)

Query: 471  KGVGRPPPAADALQSSGESSPESAPGEGAALSLSSPDAPDRPPPRHQDTGPCLEKTPAEG 530
            +G   P P      S   SSP+ A    A   +     P  P P+   T P    TP   
Sbjct: 898  EGPATPAPKQAPALSMTSSSPKKARATPAPKGI-----PASPSPKGAPTPPA--ATPPSP 950

Query: 531  RDSPTREPGALPCACGQLPDLEDELSLLDPLPRYLKSCQDLIVPEQCRCADTRPGSEQPP 590
            +  P                         P P++  +      P        + G   P 
Sbjct: 951  KGGPA-----------------------TPSPKWAPT------PPAATPPSPKGGPATPS 981

Query: 591  LGGAASPEVLAPVSKEAADLAPTGPSPRPGPGLLLDVCTKDLADAPAEELQEKGS---PA 647
              GA +P    P S +     P+ P   P P  +     K    +PA     KG+   PA
Sbjct: 982  PKGAPTPPAATPPSPKGGPATPS-PKGAPTPPAVTPPSPK---GSPAATPFPKGASTPPA 1037

Query: 648  GPPPS-QGQPAARP-PKEVPASRLAQQLREEGW----NLQTSESLTLAEVYLMMGKPSKL 701
              PPS +G PAA P PK  P +  A     +G     +L+ + +   A      G P+  
Sbjct: 1038 ATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATP 1097

Query: 702  QLEYDWLGPGRQDPRP-GSLPTALHKQRLLSCLLKLISTEVNPKLALEANTISTASVRPA 760
              +   + P    P P G L T  HK           +T  +PK  L       A   PA
Sbjct: 1098 SPKGAPMPPAATPPSPKGGLATPPHK----GAPTTPAATPPSPKGGLATPPPKGAPTTPA 1153

Query: 761  QEEQS-----MTPPGK-VVTVSSRSPRCPRNQASLRSSKTFPPSSAPCSSGLRNPPRP-- 812
                S      TPP K   T  + +P  P+   +  S K  P + A        PP P  
Sbjct: 1154 ATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPA------ATPPSPKG 1207

Query: 813  -LLVPGPSSTGSNDSDGGLFAVPTTLPPNSRHGKLFSPSKEAELTFRQHLNSISMQSDFF 871
             L  P P          G    P   PP+ + G L +PS +   T        S +    
Sbjct: 1208 GLATPSPK---------GAPTTPAATPPSPK-GGLATPSPKGAPT-TPAATPPSPKGGPA 1256

Query: 872  LPKPRKLRNRHLRKPLVVQRTLLPRPSENQSHNVCSFSILSNSSVTGRGSFRPIQSSLTK 931
             P P+         P  ++  L   P +   +     ++++  S  G  +  P + + T 
Sbjct: 1257 TPPPKGAPTPPAATPPSLKGGLATPPHKGAPNP----AVVTPPSPKGGPATSPPKGAPTP 1312

Query: 932  AALSRPIVPKVLPPQATSHLASAIDLAATSAGILSGNP-LPALDTEGLSGISPLSSDEVT 990
             A + P  PK  P   T     A    A +     G P LPA       G +  SS E  
Sbjct: 1313 PAATPP-SPKGSP--GTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKE-- 1367

Query: 991  GAISGQDSTGTHQDGDTLPTVGGSDPFVSIPSRPEQEPVADSFQGSSV------LSLSEL 1044
               +   +T +H+ G  +            P  P++ P   S +G         LS  + 
Sbjct: 1368 -GPTPPAATPSHKGGPAM-----------TPPSPKRGPAIPSPKGDPTSPAVIPLSPKKA 1415

Query: 1045 PKAPL-QNGLSIPLSSSESSSTRLSPPDVSALLDISLPGPPEDALSQGEPATHISDSIIE 1103
            P  P+ + G + P      S   L+PP   A+  +SL   P  +  +G PAT  S     
Sbjct: 1416 PATPVTREGAATP------SKGDLTPP---AVTPVSLKKAPATSAPKGGPATPSS----- 1461

Query: 1104 IAISSGQYGEGVPLSPAKLNGSDSSKSLPSPSSSPQPHWIASPTHDPQWYPSDSTDSSLS 1163
                     +G P  PA         + PSP   P P  +A+ +  P+  P+        
Sbjct: 1462 ---------KGDPTLPA--------VTPPSPKEPPAPKQVAT-SSSPKKAPATPAPMGAP 1503

Query: 1164 SLFASFISPEKSRKMLPTP 1182
            +L A  + P   +++  TP
Sbjct: 1504 TLPA--VIPSSPKEVPATP 1520



 Score = 34.7 bits (78), Expect = 0.60
 Identities = 30/98 (30%), Positives = 38/98 (38%), Gaps = 27/98 (27%)

Query: 45   TKRDEKTPRAGADGPPAPPGAPQAPSPPQGSPQDQHHFLRSSVRPQSKRPRKDPPSAVGS 104
            T   +  P   A  PP+P G P  P PP+G+P                 P   PPS  G 
Sbjct: 1234 TPSPKGAPTTPAATPPSPKGGPATP-PPKGAPTP---------------PAATPPSLKG- 1276

Query: 105  GNAGGSGPRGKGAEGGGSSSGNVSGVAPAAPAGGSRSS 142
               G + P  KGA        N + V P +P GG  +S
Sbjct: 1277 ---GLATPPHKGAP-------NPAVVTPPSPKGGPATS 1304



 Score = 32.7 bits (73), Expect = 2.3
 Identities = 25/90 (27%), Positives = 35/90 (38%), Gaps = 19/90 (21%)

Query: 45   TKRDEKTPRAGADGPPAPPGAPQAPSPPQGSPQDQHHFLRSSVRPQSKRPRKDPPSAVGS 104
            T   +  P   A  PP+P G+P  P PP+G+P                 P   PPS  G+
Sbjct: 1303 TSPPKGAPTPPAATPPSPKGSPGTP-PPKGAPTP---------------PAVTPPSPKGT 1346

Query: 105  GNAGGSGPRGKGAEGGGSSSGNVSGVAPAA 134
                 + P  K   GG ++  +  G  P A
Sbjct: 1347 PTLPATTPSSK---GGPTTPSSKEGPTPPA 1373



 Score = 32.0 bits (71), Expect = 3.9
 Identities = 28/102 (27%), Positives = 35/102 (34%), Gaps = 12/102 (11%)

Query: 42   SSGTKRDEKTPRAGADGPPAPPGAPQAPSPPQGSPQDQHHFLRSSVRPQSKRPRKDPPSA 101
            SS  K+   TP     G PA P    AP+PP  +P            P  K     P + 
Sbjct: 915  SSSPKKARATP--APKGIPASPSPKGAPTPPAATPPSPK---GGPATPSPKWAPTPPAAT 969

Query: 102  VGSGNAGGSGPRGKGAEGGGSSSGNVSGVAPAAPAGGSRSSS 143
              S   G + P  KGA              P +P GG  + S
Sbjct: 970  PPSPKGGPATPSPKGAP-------TPPAATPPSPKGGPATPS 1004



 Score = 31.2 bits (69), Expect = 6.6
 Identities = 36/128 (28%), Positives = 47/128 (36%), Gaps = 37/128 (28%)

Query: 45   TKRDEKTPRAGADGPPAPPGAPQAPSP-------------PQGSPQDQHHFLRSSVRPQS 91
            T   +  P   A  PP+P G P  PSP             P+GSP     F + +  P  
Sbjct: 979  TPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPA-ATPFPKGASTP-- 1035

Query: 92   KRPRKDPPSAVGSGNAGGSGPRGKGA----------EGGGSSSGNVSG------VAPAAP 135
              P   PPS  GS  A    P  KGA            GG ++ ++ G        P +P
Sbjct: 1036 --PAATPPSPKGSPAA---TPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSP 1090

Query: 136  AGGSRSSS 143
             GG  + S
Sbjct: 1091 KGGPATPS 1098



 Score = 31.2 bits (69), Expect = 6.6
 Identities = 24/89 (26%), Positives = 31/89 (34%), Gaps = 8/89 (8%)

Query: 52   PRAGADGPPAPPGAPQAPSPPQGSPQDQHHFLRSSVRPQSKRPRKDPPSAVGSGNAGGSG 111
            P   A  PP+P G P  PS P+G+P        ++  P  K     PP          + 
Sbjct: 1080 PTPPAATPPSPKGGPATPS-PKGAPMPP-----AATPPSPKGGLATPPHKGAPTTPAATP 1133

Query: 112  PRGKGAEGGGSSSG--NVSGVAPAAPAGG 138
            P  KG        G        P +P GG
Sbjct: 1134 PSPKGGLATPPPKGAPTTPAATPPSPKGG 1162



 Score = 31.2 bits (69), Expect = 6.6
 Identities = 30/107 (28%), Positives = 35/107 (32%), Gaps = 27/107 (25%)

Query: 52   PRAGADGPPAPPGAPQAPSPPQGSPQDQHHFLRSSVRPQSKRPRKDPPSAVGSGNAGGSG 111
            P      PP+P G P A SPP+G+P                 P   PPS  GS       
Sbjct: 1287 PNPAVVTPPSPKGGP-ATSPPKGAPTP---------------PAATPPSPKGSPGT---- 1326

Query: 112  PRGKGAEGGGSSSGNVSGVAPAAPAGGSRSSSRNLGSSGGEKEEGKK 158
            P  KGA            V P +P G     +    S GG      K
Sbjct: 1327 PPPKGAP-------TPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSK 1366


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 56.2 bits (134), Expect = 2e-07
 Identities = 144/620 (23%), Positives = 219/620 (35%), Gaps = 94/620 (15%)

Query: 582  TRPGSEQPPLGGAASPEVLAPVSKEAADLA---PTGPSPRPGPGLLLDVCTKDLADAPAE 638
            +RP     PL    SP +L P+      ++     G S   GPG  +          P  
Sbjct: 2118 SRPSMSPTPLDRCRSPGMLEPLGSSRTPMSVLQQAGGSMMDGPGPRIP--DHQRTSVPEN 2175

Query: 639  ELQEKGSPAGPPPSQGQPAARPPKEVPASRLAQQLREEG-----WNLQTSESLTLAEVYL 693
              Q + + A    S G   ARPP  + A+ LA ++ +        +L+T+ +  LA   +
Sbjct: 2176 HAQSRIALALTAISLG--TARPPPSMSAAGLAARMSQVPAPVPLMSLRTAPAANLAS-RI 2232

Query: 694  MMGKPSKLQLEYDWLGPGRQDPRPGSLPTALHKQRLLSCLLKLISTEVNPKLALEANTIS 753
                 + + L            R  ++PTA++     +          +P+ A+  + ++
Sbjct: 2233 PAASAAAMNLA---------SARTPAIPTAVNLADSRTPAAAAAMNLASPRTAVAPSAVN 2283

Query: 754  TASVRPAQEEQSMTPPGKVVTVSSRSPRCPRNQASLRSSKTFPPSSAPCSSGLRNPPRPL 813
             A  R        TP    V ++           SL  S T PP++A   S  R P  P 
Sbjct: 2284 LADPR--------TPTAPAVNLAGARTPAALAALSLTGSGT-PPTAANYPSSSRTPQAPA 2334

Query: 814  L--VPGPSSTGSNDSDGGLFAVPTTLPPNSRHGKLFSPSKEAELTFRQHLNSISMQSDFF 871
               + GP S  +            T P N    +  +    A LT  +   ++S  +   
Sbjct: 2335 SANLVGPRSAHA------------TAPVNIAGSRTAAALAPASLTSARMAPALSGAN--- 2379

Query: 872  LPKPRKLRNRHLR------KPLVVQRTLLPRPSENQSHNVCSFSILSNSSVTGRGSFRPI 925
            L  PR   + + R       PL+ +      PS      + S    S SS  G+    P 
Sbjct: 2380 LTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQA---PS 2436

Query: 926  QSSLTKAA-LSRPIVPKVLPPQATSHLASAIDLAATSAGILSGNPLPALDTEGLSGISPL 984
            QS L  A    R  VP     Q+   +A    +A + +            + G    +  
Sbjct: 2437 QSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSL-----------SSGAVATTTS 2485

Query: 985  SSDEVTGAISGQDSTGTHQD-GDTLPTVGGSDPFVSIPSRPEQEPVADSFQGSSVLSLSE 1043
            S+ +  G +S       H D G+   + G   P      +P +E  + S   SS  S S 
Sbjct: 2486 SAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSS 2545

Query: 1044 LPKAPLQNGLSIPLSSSESSSTRLSPPDVSALLDISLPGPPEDALSQGEPATHISDSIIE 1103
                          SSS SSS+  S    S     SLP  PE AL +    T        
Sbjct: 2546 --------------SSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKE--- 2588

Query: 1104 IAISSGQYGEGVPLSPAKLNGSDSSKSLPSPSSSPQPHWIASPTHDPQWYPSDSTDSSLS 1163
             A+  G+  E  P    + + S SS S  S SSS      +S +       S S+ SS S
Sbjct: 2589 -AVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSS-----SSSSSSSSS 2642

Query: 1164 SLFASFISPEK-SRKMLPTP 1182
            S  +S  SP K   + LP P
Sbjct: 2643 SSSSSSPSPAKPGPQALPKP 2662



 Score = 40.0 bits (92), Expect = 0.014
 Identities = 116/529 (21%), Positives = 178/529 (33%), Gaps = 104/529 (19%)

Query: 472  GVGRPPPAADALQSSGESSPESAPGEGAALSLSSPDAPDRPPPRHQDTGPCLEKTPAEGR 531
            G  RPPP+  A   +   S   AP     + L S                 L   PA   
Sbjct: 2191 GTARPPPSMSAAGLAARMSQVPAP-----VPLMS-----------------LRTAPAANL 2228

Query: 532  DS--PTREPGALPCACGQLPDLEDELSLLD------PLPRYLKSCQDLIVPEQCRCADTR 583
             S  P     A+  A  + P +   ++L D           L S +  + P     AD R
Sbjct: 2229 ASRIPAASAAAMNLASARTPAIPTAVNLADSRTPAAAAAMNLASPRTAVAPSAVNLADPR 2288

Query: 584  -PGSEQPPLGGAASPEVLAPVSKEAADLAPTG---PSPRPGPGLLLDVCTKDLADAPAEE 639
             P +    L GA +P  LA +S   +   PT    PS    P           A A A  
Sbjct: 2289 TPTAPAVNLAGARTPAALAALSLTGSGTPPTAANYPSSSRTP----------QAPASANL 2338

Query: 640  LQEKGSPAGPP---PSQGQPAARPPKEVPASRLAQQLREEGWNLQTSESLTLAEVYLMMG 696
            +  + + A  P         AA  P  + ++R+A  L   G NL TS  + L+    + G
Sbjct: 2339 VGPRSAHATAPVNIAGSRTAAALAPASLTSARMAPAL--SGANL-TSPRVPLSAYERVSG 2395

Query: 697  KPSKLQLE---------------------------------YDWLGPGRQDPRPGSLPTA 723
            + S   L+                                    L P +  PR   +P+A
Sbjct: 2396 RTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPR-SPVPSA 2454

Query: 724  LHKQRLLSCLLKLISTEVNPKLALEANTISTASVRPAQEEQSMTPPGKVVTVS------- 776
               Q    CL+   +T V    +L +  ++T +         ++ P   V  S       
Sbjct: 2455 FSDQS--RCLIAQ-TTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPA 2511

Query: 777  SRSPRCPRNQASLRSSKTFPPSSAPCSSGLRNPPRPLLVPGPSSTGSNDSDGGLFAVPTT 836
            S   + P   A+L+ +K    SS+  SS   +          SS+GS+ SD    ++P  
Sbjct: 2512 STGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLP-- 2569

Query: 837  LPPNSRHGKLFSPSKEAELTFRQHLNSISMQSDFFLPKPRKLRNRHLRKPLVVQRTLLPR 896
            + P     ++ SP+   +   R+             P P K + R          +    
Sbjct: 2570 VQPEVALKRVPSPTPAPKEAVREGRPP--------EPTPAKRKRRSSSSSSSSSSSSSSS 2621

Query: 897  PSENQSHNVCSFSILSNSSVTGRGSFRPIQSSLTKAALSRPIVPKVLPP 945
             S + S +  S S  S+SS +   S  P  +     AL +P  PK  PP
Sbjct: 2622 SSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPP 2670



 Score = 38.5 bits (88), Expect = 0.041
 Identities = 115/456 (25%), Positives = 167/456 (36%), Gaps = 83/456 (18%)

Query: 753  STASVRPAQEEQSMTPPGKVVTVSSRSPRCPRNQASLRSSKTFPPSSAPCSSGLRNPPRP 812
            S +   P  +++S TPP +  + SS+ P+          S+T P  S   SS     P P
Sbjct: 778  SLSGSSPCPKQKSQTPPRRSRSGSSQ-PKA--------KSRTPPRRSRSSSS-----PPP 823

Query: 813  LLVPGPSSTGSNDSDGGLFAVPTTLPPNSRHGKLFSPSKEAELTFRQHLNSISMQSDFFL 872
                   S  S+ S      V +  PP  R G + SP    +    Q  +      D   
Sbjct: 824  KQKSKTPSRQSHSSSSPHPKVKSGTPP--RQGSITSPQANEQSVTPQRRSCFESSPD--- 878

Query: 873  PKPRKLRNRHLRKPLVVQRTLLPRPSENQSHNVCSFSILSNSSVTGRGSFRPIQSSLTKA 932
                         P +  RT    PS +           S SS     S  P + S +++
Sbjct: 879  -------------PELKSRT----PSRHS---------CSGSSPPRVKSSTPPRQSPSRS 912

Query: 933  ALSRPIVPKVLPPQATSHLASAIDLAATSAGILSGNPLPALDTEGLSGISPLSSDE---- 988
            +  +P V  ++ P+  SH  S    ++ S   ++    P         +SP S+ E    
Sbjct: 913  SSPQPKVKAIISPRQRSHSGS----SSPSPSRVTSRTTPRRS----RSVSPCSNVESRLL 964

Query: 989  VTGAISGQDSTGTHQDGDTLPTVGGSDPFVSIPSRPEQEPVADSFQGSSVLSLSELPKAP 1048
               + SG  S  T    +T P    S      P    Q P   S  GS      E  K  
Sbjct: 965  PRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGPSLSGSKSPCPQEKSKDS 1024

Query: 1049 LQNGL--SIPLSSSESSSTRLSPPDVS--ALLDISLPGPPEDALSQGEPATHISDSIIEI 1104
            L      S+ L +   SST   PP  S   +  + L G      SQ  P  H SD+    
Sbjct: 1025 LVQSCPGSLSLCAGVKSST---PPGESYFGVSSLQLKGQ-----SQTSP-DHRSDT---- 1071

Query: 1105 AISSGQYGEGVPLSPAKLNGSDSS-KSLPSPSSSPQPHWIASPTHDPQWYPSDSTDSSLS 1163
              SS +  +    SP+  + S +S K   S SSSP    +AS +   Q    D  + S S
Sbjct: 1072 --SSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTE-LASRSPIRQ----DRGEFSAS 1124

Query: 1164 SLFASFISPEKSR-KMLPTPIGTNSGTSLLGPSLLD 1198
             +  S +SPE+SR +   +   T    SLLG S L+
Sbjct: 1125 PMLKSGMSPEQSRFQSDSSSYPTVDSNSLLGQSRLE 1160



 Score = 38.1 bits (87), Expect = 0.054
 Identities = 41/156 (26%), Positives = 57/156 (36%), Gaps = 9/156 (5%)

Query: 380  RQLQDSCSAPMQEKVTLHLFPGENC-TLTPL-----PGVARVVHSKAFCTVHWQEGGRCK 433
            ++L    SA  QE+      P     T TPL      G +  V SK+  +      G   
Sbjct: 1543 QELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSP 1602

Query: 434  QSAKDAHVLPPAQILGIQSGQGTARGQVKCPR---SGAEGKGVGRPPPAADALQSSGESS 490
            +        P AQ     S +  A      PR   SG+  KG G  P  + + +SS E  
Sbjct: 1603 EVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHP 1662

Query: 491  PESAPGEGAALSLSSPDAPDRPPPRHQDTGPCLEKT 526
            P+S      + S   P    R PPR + +    E T
Sbjct: 1663 PKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELT 1698



 Score = 37.4 bits (85), Expect = 0.092
 Identities = 24/76 (31%), Positives = 34/76 (44%)

Query: 465  RSGAEGKGVGRPPPAADALQSSGESSPESAPGEGAALSLSSPDAPDRPPPRHQDTGPCLE 524
            RS  E K   R PP   + +SS E + ++     +  + SSP+   R PPRH+ +     
Sbjct: 1673 RSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSS 1732

Query: 525  KTPAEGRDSPTREPGA 540
              PAE   S  R   A
Sbjct: 1733 PEPAEKSRSSRRRRSA 1748



 Score = 35.8 bits (81), Expect = 0.27
 Identities = 91/418 (21%), Positives = 132/418 (31%), Gaps = 82/418 (19%)

Query: 437  KDAHVLPPAQILGIQSGQGTARGQVKCPRSGAEGKGVGRPPPAADALQSSGESSPESAPG 496
            + AH   P  I G ++    A   +   R      G     P          S+ E   G
Sbjct: 2342 RSAHATAPVNIAGSRTAAALAPASLTSARMAPALSGANLTSPRVPL------SAYERVSG 2395

Query: 497  EGAALSLSSPDAPDRPPPRHQDTGPCLEKTPAEGRDSPTREPGALPCACGQLPDLEDELS 556
                   +SP   DR   R   + P   +  +E   SP+   G  P             S
Sbjct: 2396 R------TSPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQ-----------S 2438

Query: 557  LLDPLPRYLKSCQDLIVPEQCRC--ADTRPGSEQPPLGGAASPEVLAPVSKEAADLAPTG 614
            LL P     +S       +Q RC  A T P +    L   A    +A  +  A D    G
Sbjct: 2439 LLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGA----VATTTSSAGD--HNG 2492

Query: 615  PSPRPGPGLLLDVCTKDLADAPAEELQEKGSPAGPPPSQGQPAARPPKEVPASRLAQQLR 674
                P PG+            P  ++ E      PP S G   A+ P  + A + A++ R
Sbjct: 2493 MLSVPAPGV------------PHSDVGE------PPASTG---AQQPSALAALQPAKERR 2531

Query: 675  EEGWNLQTSESLTLAEVYLMMGKPSKLQLEYDWLGPGRQDPRPGSLPTALHKQRLLSCLL 734
                +  +S S + +         S         G    D    SLP           L 
Sbjct: 2532 SSSSSSSSSSSSSSSSSSSSSSSSS---------GSSSSDSEGSSLPVQPEV-----ALK 2577

Query: 735  KLISTEVNPKLAL-EANTISTASVRPAQEEQSMTPPGKVVTVSSRSPRCPRNQASLRSSK 793
            ++ S    PK A+ E         +  +   S +      + SS S     + +S  SS 
Sbjct: 2578 RVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2637

Query: 794  TFPPSSAPCSSGLRNPPRPLLVPGPSSTGSNDSDGGLFAVPTTLPPNSRHGKLFSPSK 851
            +   SS+  SS     P P  +P P+S             P   PP  R  +  SP K
Sbjct: 2638 SSSSSSSSSSSPSPAKPGPQALPKPAS-------------PKKPPPGERRSR--SPRK 2680



 Score = 34.3 bits (77), Expect = 0.78
 Identities = 48/243 (19%), Positives = 84/243 (34%), Gaps = 34/243 (13%)

Query: 452  SGQGTARGQVKCPRSGAEGKGVGRPPPAADALQSSGESSPESAPGEGAALSLSSPDAPDR 511
            S  G   G +  P  G     VG PP +  A Q S  ++ + A    ++ S SS  +   
Sbjct: 2485 SSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSS- 2543

Query: 512  PPPRHQDTGPCLEKTPAEGRDSPTREPGALPCACGQLPDLEDELSLL---DPLPRYLKSC 568
                   +      + + G  S   E  +LP        ++ E++L     P P   ++ 
Sbjct: 2544 -----SSSSSSSSSSSSSGSSSSDSEGSSLP--------VQPEVALKRVPSPTPAPKEAV 2590

Query: 569  QDLIVPEQCRCADTRPGSEQPPLGGAASPEVLAPVSKEAADLAPTGPSPRPGPGLLLDVC 628
            ++   PE       R  S       ++S    +  S  ++  + +  S            
Sbjct: 2591 REGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS------------ 2638

Query: 629  TKDLADAPAEELQEKGSPAGPPPSQGQPAARPPKEVPASRLAQQLREEGWNLQTSESLTL 688
                  + +       SPA P P      A P K  P  R ++  R+   +L+ S SL+ 
Sbjct: 2639 -----SSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSY 2693

Query: 689  AEV 691
            + V
Sbjct: 2694 SPV 2696



 Score = 33.1 bits (74), Expect = 1.7
 Identities = 31/120 (25%), Positives = 49/120 (40%), Gaps = 15/120 (12%)

Query: 51   TPRAGADGPPAPPGAPQAPSPPQGSPQDQHHFLRSSVRPQSKRPRKDPPSAVGSGNAGGS 110
            +PR    G      +P+    P+ +P+ Q      S    S  P+   P A+   +  GS
Sbjct: 1592 SPRRSRSG-----SSPEVKDKPRAAPRAQ------SGSDSSPEPKAPAPRALPRRSRSGS 1640

Query: 111  GPRGKGAEGGGSSSGNVSGVAPAAPAGGSRSSSRNLGSSGGEKEEGKKVRRQWESWSTED 170
              +G+G    GSSS   S   P      SR++ R   SS   K + +   R+  S S+ +
Sbjct: 1641 SSKGRGPSPEGSSSTESSPEHPPK----SRTARRGSRSSPEPKTKSRTPPRRRSSRSSPE 1696



 Score = 32.3 bits (72), Expect = 3.0
 Identities = 39/140 (27%), Positives = 53/140 (37%), Gaps = 14/140 (10%)

Query: 12   EDGLKKLGKRAADEESLEG--EGAGGADA---AEESSGTKRDEKTPRAG---ADGPPAPP 63
            +DGL +   R +   S  G  +G+G       +  S G K   +TP  G    D  P P 
Sbjct: 1428 KDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPK 1487

Query: 64   GAPQAPSPPQGSPQDQHHFLRSSVRPQSKRPRKDPPSAVGSGNAGGSGPRGKGAEGGGSS 123
              PQ P P   SP          + PQ  R R    S+V       + P G+ +  G S 
Sbjct: 1488 ALPQTPRPRSRSPSSP-ELNNKCLTPQ--RERSGSESSVDQKTVART-PLGQRSRSGSSQ 1543

Query: 124  SGNVSGVAPAAPAGGSRSSS 143
              +V     A+P   S S S
Sbjct: 1544 ELDVK--PSASPQERSESDS 1561



 Score = 32.3 bits (72), Expect = 3.0
 Identities = 52/218 (23%), Positives = 77/218 (35%), Gaps = 45/218 (20%)

Query: 465  RSGAEG----KGVGRPPPAADALQSSGES---SPESAPGEGAALSLSSPD--APDRPPPR 515
            RSG+E     K V R P    +   S +     P ++P E +  S SSPD  A  R P R
Sbjct: 1516 RSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQERSE-SDSSPDSKAKTRTPLR 1574

Query: 516  HQDTGPCLEKTPAEGRDSPTREPGALPCACGQLPDLEDELSLLDPLPRYLKSCQDLIVPE 575
             +       +  ++ R SP R         G  P+++D+       PR     Q      
Sbjct: 1575 QRSRSGSSPEVDSKSRLSPRRSRS------GSSPEVKDK-------PRAAPRAQS----- 1616

Query: 576  QCRCADTRPGSEQPPLGGAASPEVLAPVSKEAADLAPTGPSPRPGPGLLLDVCTKDLADA 635
                     GS+  P   A +P  L   S+  +     GPSP                  
Sbjct: 1617 ---------GSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSS-----TESSPEHP 1662

Query: 636  PAEELQEKGSPAGPPPSQGQPAARPPKEVPASRLAQQL 673
            P      +GS + P P   +  +R P    +SR + +L
Sbjct: 1663 PKSRTARRGSRSSPEP---KTKSRTPPRRRSSRSSPEL 1697



 Score = 32.3 bits (72), Expect = 3.0
 Identities = 26/131 (19%), Positives = 52/131 (39%), Gaps = 5/131 (3%)

Query: 20   KRAADEESLEGEGAGGADAAEESSGTKRDEKTPRAGADGPPAPPGAPQAPSPPQGSPQDQ 79
            +R++   S     +  + ++  SS +     +   G+  P  P  A +    P  +P++ 
Sbjct: 2530 RRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEA 2589

Query: 80   HHFLRSSVRPQSKRPRKDPPSAVGSGNAGGSGPRGKGAEGGGSSSGNVSGVAPAAPAGGS 139
                R      +KR R+   S+  S ++  S      +    SSS + S  + ++ +  S
Sbjct: 2590 VREGRPPEPTPAKRKRRSSSSSSSSSSSSSS-----SSSSSSSSSSSSSSSSSSSSSSSS 2644

Query: 140  RSSSRNLGSSG 150
             SSS +    G
Sbjct: 2645 SSSSPSPAKPG 2655



 Score = 32.0 bits (71), Expect = 3.9
 Identities = 47/204 (23%), Positives = 74/204 (36%), Gaps = 11/204 (5%)

Query: 474 GRPPPAADALQSSGESSPESAPGEGAALSLSSPDAPDRPPPRHQDTGPCLEKTPAEGRDS 533
           GR P  A   +  G++ P S PG  +    SSP+   + P    +     +K  +  R S
Sbjct: 293 GRSPSPASGRRGEGDA-PFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPS 351

Query: 534 PTREPGAL-PCACGQLPDL-EDELSLLDPLPRYLKSCQDLIVP-EQCRCADTRPGSEQPP 590
           P+ E  +  P      P L E       PL     S + +  P E     D  P      
Sbjct: 352 PSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEK 411

Query: 591 LGGAASPEVLAP------VSKEAADLAPTGPSPRPGPGLLLDVCTKDLADAPAEELQEKG 644
           L  ++S E   P      VS+ A+  +P  P P P PG   ++ +   +   +    ++ 
Sbjct: 412 LPQSSSSESSPPSPQPTKVSRHASS-SPESPKPAPAPGSHREISSSPTSKNRSHGRAKRD 470

Query: 645 SPAGPPPSQGQPAARPPKEVPASR 668
                 PS+    +R P      R
Sbjct: 471 KSHSHTPSRRMGRSRSPATAKRGR 494



 Score = 31.6 bits (70), Expect = 5.0
 Identities = 88/357 (24%), Positives = 120/357 (33%), Gaps = 83/357 (23%)

Query: 484  QSSGESSPESAP------GEGAALSLSSP--DAPDRPPPRHQDTGPC-------LEKTPA 528
            +SSG SS E +P      G  +  S+SSP  DA  R P R + +          L +TP+
Sbjct: 1377 RSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTPS 1436

Query: 529  E----GRDSPTREPGALPCA---CGQLPDLEDELSLLDPLPRYLKSCQDLIVPEQCRC-A 580
                 G     R+    P      G  P ++D       +PR          P + R   
Sbjct: 1437 RRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKD-------IPR---------TPSRGRSEC 1480

Query: 581  DTRPGSEQPPLGGAASPEVLAPVSKEAADLAPTGPSPRPGPGLLLDVCTKDLADAPAEEL 640
            D+ P  E   L     P   +P S E  +   T    R G    +D   K +A  P  + 
Sbjct: 1481 DSSP--EPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVD--QKTVARTPLGQR 1536

Query: 641  QEKGSPAGPPPSQGQPAARPPKEVPASRLAQQLREEGWNLQTSESLTLAEVYLMMGKPSK 700
               GS         +P+A P           Q R E  +   S++ T             
Sbjct: 1537 SRSGSSQ---ELDVKPSASP-----------QERSESDSSPDSKAKTRT----------- 1571

Query: 701  LQLEYDWLGPGRQDPRPGSLPTALHKQRLLSCLLKLIST---EVNPKLALEANTISTASV 757
                     P RQ  R GS P    K RL     +  S+   +  P+ A  A + S +S 
Sbjct: 1572 ---------PLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSP 1622

Query: 758  RPAQEEQSMTPPGKVVTVSS--RSPRCPRNQASLRSSKTFPPSSAPCSSGLRNPPRP 812
             P        P       SS  R P  P   +S  SS   PP S     G R+ P P
Sbjct: 1623 EPKAPAPRALPRRSRSGSSSKGRGPS-PEGSSSTESSPEHPPKSRTARRGSRSSPEP 1678


>gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens]
          Length = 1003

 Score = 55.5 bits (132), Expect = 3e-07
 Identities = 170/662 (25%), Positives = 232/662 (35%), Gaps = 122/662 (18%)

Query: 470  GKGVGRPPPAADALQSSGESSPESAPGEGAALSLSSPDAPDRPPPRHQDTGPCLEKTPAE 529
            G G   PP  AD + S G SSP   P   A        +P  PPP            PA 
Sbjct: 180  GPGGLFPPRLADPVPSGGSSSPRFLPRGNA-------PSPAPPPP------------PAI 220

Query: 530  GRDSPTREPGA------LPCACGQLPDLEDELSLLDPLPRYLKSCQDLIVPEQCRCADTR 583
              ++P+   GA      +P   G  P      S   P    L  C D + P     ++  
Sbjct: 221  SLNAPSYNWGAALRSSLVPSDLGSPP--APHASSSPPSDPPLFHCSDALTPPPLPPSNNL 278

Query: 584  PG----SEQPPLGGAAS--PEVLAPVSKEAADLAPTGPSPRPGPGLLLDVCTKDLADAPA 637
            P     + QPP+  A    P VL P+       APT   P   P L   + +   A A A
Sbjct: 279  PAHPGPASQPPVSSATMHLPLVLGPLGG-----APTVEGPGAPPFLASSLLS---AAAKA 330

Query: 638  EELQEKGSPAGPPPSQGQPAARPPKEVPASRLAQQLREEGWNLQTSESLTLAEVYLMMGK 697
            +       P  PPPS  Q   RP  + P++  +  LR      Q           L+ G+
Sbjct: 331  QH------PPLPPPSTLQ-GRRPRAQAPSASHSSSLRPS----QRRPRRPPTVFRLLEGR 379

Query: 698  PSKLQLEYDWLGPGRQDPRPGSLPTALHKQRLLSCLLKLISTEVNPKLALEANTISTASV 757
              +         P    P+P SLP     Q +L  +L L+       L     + S  S 
Sbjct: 380  GPQTPRRSRPRAPA-PVPQPFSLPEP--SQPILPSVLSLLG------LPTPGPSHSDGSF 430

Query: 758  RPAQEEQSMTPPGKVVTVSSRSPRCPRN--QASLRSSKTFPPSSAPCSSGLRNPPRPLLV 815
                 +  + PP    T+SS SP  PR+  Q SL  + +   SS P   G   PP     
Sbjct: 431  NLLGSDAHLPPP---PTLSSGSPPQPRHPIQPSLPGTTSGSLSSVP---GAPAPPAASKA 484

Query: 816  P-GPSSTGSNDSDG-GLFAVPTTLPPNSRHGKLFS-PSKEAELT-----FRQHLNSISMQ 867
            P  PS    + S+G G+ A P    P    G+ F  PS E  L      F   L ++ + 
Sbjct: 485  PVVPSPVLQSPSEGLGMGAGPACPLPPLAGGEAFPFPSPEQGLALSGAGFPGMLGALPLP 544

Query: 868  SDFFLPKPRKLRNRHLRKPLV------VQRTLLP---------RPSENQSHNVCSFSILS 912
                 P P  L N  L   L           LLP          P E +  ++   S+L 
Sbjct: 545  LSLGQPPPSPLLNHSLFGVLTGGGGQPPPEPLLPPPGGPGPPLAPGEPEGPSLLVASLLP 604

Query: 913  NSSVTGRGSFRPIQSSLTKAALSRP--IVPKVLPPQATSHLASAIDLAATSAGILSGNPL 970
                       P  S L     + P  ++   LP  A    A   + +A  AG  SG P 
Sbjct: 605  -----------PPPSDLLPPPSAPPSNLLASFLPLLALGPTAGDGEGSAEGAGGPSGEPF 653

Query: 971  PALDTEGLSGISPLSSDEVTGAISGQDSTGTHQDGDTLPTVGGSDPFVSIPSRPEQEPVA 1030
              L         PLS+     A++            TL    G+ P   + S P+  P  
Sbjct: 654  SGLGDLSPLLFPPLSAPPTLIALNSALLAA------TLDPPSGTPPQPCVLSAPQPGPPT 707

Query: 1031 DSFQGSSV-LSLSELPKAPLQNG-----LSIPLSSS---ESSSTRLSPPDVSALLDISLP 1081
             S   ++     S L KAP  +G     LS  L +S   + SS   SP  + +LL    P
Sbjct: 708  SSVTTATTDPGASSLGKAPSNSGRPPQLLSPLLGASLLGDLSSLTSSPGALPSLL--QPP 765

Query: 1082 GP 1083
            GP
Sbjct: 766  GP 767



 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 192/760 (25%), Positives = 258/760 (33%), Gaps = 170/760 (22%)

Query: 480  ADALQSSGESSPESAPGEGAALSL---SSPDAPD-RPPPRHQDTGPCLEKTPAEGRDSPT 535
            A   +S   +   S+PGEGA+  +    SP  P  RPP R   T      TP  G   P 
Sbjct: 111  ATLYRSMETTCSHSSPGEGASPQMFHTVSPGPPSARPPCRVPPT------TPLNG--GPG 162

Query: 536  REPGALPCACGQLPDLEDELSLLDPLPRYLKSCQDLIVPEQCRCADTRP--GSEQP---P 590
              P   P      P L     L  P                 R AD  P  GS  P   P
Sbjct: 163  SLPPEPPSVSQAFPTLAGPGGLFPP-----------------RLADPVPSGGSSSPRFLP 205

Query: 591  LGGAASPEVLAPVSKEAADLAPTGPSPRPGPGLLLDVCTKDLADAPAEELQEKGSPAGPP 650
             G A SP   AP    A  L    PS   G  L   +   DL   PA        P+ PP
Sbjct: 206  RGNAPSP---APPPPPAISL--NAPSYNWGAALRSSLVPSDLGSPPAPH-ASSSPPSDPP 259

Query: 651  PSQGQPAARPPKEVPASRLAQQLREEGWNLQTSESLTLAEVYLMMGKPSKLQLEYDWLGP 710
                  A  PP   P++ L       G   Q   S     + L++G           LG 
Sbjct: 260  LFHCSDALTPPPLPPSNNLP---AHPGPASQPPVSSATMHLPLVLGP----------LGG 306

Query: 711  GRQDPRPGSLPTALHKQRLLSCLLKLISTEVNPKLALEA--------NTISTASVRPAQE 762
                  PG+ P       LLS   K     + P   L+         +   ++S+RP+Q 
Sbjct: 307  APTVEGPGAPP--FLASSLLSAAAKAQHPPLPPPSTLQGRRPRAQAPSASHSSSLRPSQ- 363

Query: 763  EQSMTPPGKVVTVSSRSPRCPRNQASLRSSKTFPPSSAPCSSGLRNPPRPLL-------- 814
             +   PP     +  R P+ PR       S+   P+  P    L  P +P+L        
Sbjct: 364  RRPRRPPTVFRLLEGRGPQTPRR------SRPRAPAPVPQPFSLPEPSQPILPSVLSLLG 417

Query: 815  --VPGPS-STGSND---SDGGLFAVPTT---LPPNSRHGKLFSPSKEAELTFRQHLNSIS 865
               PGPS S GS +   SD  L   PT     PP  RH     PS            S S
Sbjct: 418  LPTPGPSHSDGSFNLLGSDAHLPPPPTLSSGSPPQPRHP--IQPSLPG-------TTSGS 468

Query: 866  MQSDFFLPKPRKLRNRHLRKPLVVQRTLLPRPSENQSHN---VCSFSILSNSSVTGRGSF 922
            + S    P P         K  VV   +L  PSE         C    L+       G  
Sbjct: 469  LSSVPGAPAPPA-----ASKAPVVPSPVLQSPSEGLGMGAGPACPLPPLAG------GEA 517

Query: 923  RPIQSSLTKAALSRPIVPKVLPPQATSHLASAIDLAATSAGILSGNPLPALDTEGLSGIS 982
             P  S     ALS                       A   G+L   PLP   + G    S
Sbjct: 518  FPFPSPEQGLALS----------------------GAGFPGMLGALPLPL--SLGQPPPS 553

Query: 983  PLSSDEVTGAISGQDSTGTHQDGDTLPTVGGSDPFVSIPSRPEQEPVADSFQGSSVLSLS 1042
            PL +  + G ++G    G       LP  GG  P ++ P  PE         G S+L  S
Sbjct: 554  PLLNHSLFGVLTG--GGGQPPPEPLLPPPGGPGPPLA-PGEPE---------GPSLLVAS 601

Query: 1043 ELPKAPLQNGLSIPLSSSESSSTRLSPPDVSALLDISLPGPPEDALS-----QGEPATHI 1097
             LP  P      +P  S+  S+   S   + AL   +  G  E +        GEP + +
Sbjct: 602  LLPPPPSD---LLPPPSAPPSNLLASFLPLLALGPTA--GDGEGSAEGAGGPSGEPFSGL 656

Query: 1098 SD--SIIEIAISSGQYGEGVPLSPAKLNGSDSSKSLPSPSSS-PQPHWIASPTHDPQWYP 1154
             D   ++   +S+       P +   LN +  + +L  PS + PQP  +++P   P   P
Sbjct: 657  GDLSPLLFPPLSA-------PPTLIALNSALLAATLDPPSGTPPQPCVLSAPQPGP---P 706

Query: 1155 SDSTDSSLSSLFASFISPEKSRKMLPTP-IGTNSGTSLLG 1193
            + S  ++ +   AS +    S    P   +    G SLLG
Sbjct: 707  TSSVTTATTDPGASSLGKAPSNSGRPPQLLSPLLGASLLG 746



 Score = 33.1 bits (74), Expect = 1.7
 Identities = 30/95 (31%), Positives = 37/95 (38%), Gaps = 22/95 (23%)

Query: 52  PRAGADGPPAPPGAPQAPSPPQGSPQDQHHFLRSSVRPQSKRPRKDPPSAVGSG------ 105
           P  G  GPP  PG P+ PS            L +S+ P        PPSA  S       
Sbjct: 578 PPPGGPGPPLAPGEPEGPS-----------LLVASLLPPPPSDLLPPPSAPPSNLLASFL 626

Query: 106 ---NAGGSGPRGKG-AEGGGSSSGN-VSGVAPAAP 135
                G +   G+G AEG G  SG   SG+   +P
Sbjct: 627 PLLALGPTAGDGEGSAEGAGGPSGEPFSGLGDLSP 661



 Score = 33.1 bits (74), Expect = 1.7
 Identities = 34/122 (27%), Positives = 48/122 (39%), Gaps = 29/122 (23%)

Query: 62  PPGAPQAPSPPQGSPQDQHHFLRSSVRPQSKRPRKDPPSAVGSGNAGGSGP-------RG 114
           PP  P+AP  P  SP        S++ P+  RP   P SA+   +     P       RG
Sbjct: 804 PPEQPEAPCLPPESP-------ASALEPEPARP---PLSALAPPHGSPDPPVPELLTGRG 853

Query: 115 KGAEG--GGSSSGNVSGVAPAAPAGGSRSSSR--------NLGSSGGEKEEGKKVRRQWE 164
            G  G  GG     ++G   A PA G +  SR          G+ GG   + ++  R+  
Sbjct: 854 SGKRGRRGGGGLRGING--EARPARGRKPGSRREPGRLALKWGTRGGFNGQMERSPRRTH 911

Query: 165 SW 166
            W
Sbjct: 912 HW 913



 Score = 30.8 bits (68), Expect = 8.6
 Identities = 18/46 (39%), Positives = 23/46 (50%), Gaps = 4/46 (8%)

Query: 54  AGADGPPAPPGAP-QAPSPPQGSPQDQHHFLRSSVRPQSKRPRKDP 98
           A A  PP PP +  Q   P   +P   H    SS+RP  +RPR+ P
Sbjct: 328 AKAQHPPLPPPSTLQGRRPRAQAPSASHS---SSLRPSQRRPRRPP 370


>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
            sapiens]
          Length = 5537

 Score = 55.1 bits (131), Expect = 4e-07
 Identities = 166/728 (22%), Positives = 238/728 (32%), Gaps = 111/728 (15%)

Query: 476  PPPAADALQSSGESSPESAPGEGAALSLSSPDAPDRPPPRHQDTGPCLEKTP-AEGRDSP 534
            PPP A  L    E  P S   E   LS    ++P  PPP      P  E +P +   +SP
Sbjct: 460  PPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESP 519

Query: 535  TREPGALPCACGQLPDLEDELS---LLDPLPRYLKSCQDLIVPEQCRCADTRPGSEQPPL 591
               P   P +    P LE  LS      PL    +       PE+       P S  P  
Sbjct: 520  LSPPEESPPS----PALETPLSPPPEASPLSPPFEESPLSPPPEEL------PTSPPPEA 569

Query: 592  GGAASPEVLAPVSKEAADLAPTGPSPRPGPGLLLDVCTKDLADAPAEELQEKGSPAGPPP 651
               + P   +P+S    +   +  SP P    L     +     P EE     SP  PPP
Sbjct: 570  SRLSPPPEESPMSPPPEE---SPMSPPPEASRLFPPFEESPLSPPPEE-----SPLSPPP 621

Query: 652  S--------QGQPAARPPKEVPASRLAQQLREEGWNLQTSESLTLAEVYLM---MGKPSK 700
                     +  P + PP+E P S   +  R     + +  S    E  L       P+ 
Sbjct: 622  EASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTS 681

Query: 701  LQLEYDWLGPGRQD----PRPGSLPTALHKQRLLSCLLKLISTEVNPKLALEANTISTAS 756
               E   L P  +D    P P   P +   +  L  L      E +P L L         
Sbjct: 682  PPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSL----PLEESPLLPLP----EEPQ 733

Query: 757  VRPAQEEQSMTPPGKVVTVSSRSPRCPRNQASLRSSKTFPPSSAPCSSGLRNPPR----- 811
            + P  E   ++P  +   +S R P  P            P    PC   +   P      
Sbjct: 734  LCPRSEGPHLSPRPEEPHLSPR-PEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQA 792

Query: 812  --PLLVPGPSS--TGSNDSDGGLFAVP--TTLPPNSRHGKLFSPSKEAELTFRQHLNSIS 865
              P L P P          +  L  VP    L P      L   S+E  L+ R   + +S
Sbjct: 793  EGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLS 852

Query: 866  --MQSDFFLPKPRKLRNRHLRKPLVVQRTLLPRPSENQSHNVCSFSILSNSSVTGRGSFR 923
              ++     P+P K      + P   +  L P P E     +     LS     G     
Sbjct: 853  PELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSE---PGEPPLS 909

Query: 924  PIQSSLTKAALSRP-IVPKVLPPQATSHLASAIDLAATSAGILSGNPLPALDTE-GLSG- 980
            P+   L  +    P + P+++PP       S I  AA    +   +PL  L+   G  G 
Sbjct: 910  PLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPAL---SPLGELEYPFGAKGD 966

Query: 981  ---ISPLSSDEVTGAISGQDSTGTHQDGDTLP----------TVGGSDPFVSIPSRPEQE 1027
                SPL++  +   IS         D + +P           VG + P +  P  P+  
Sbjct: 967  SDPESPLAAPILETPISPPPEANC-TDPEPVPPMILPPSPGSPVGPASPILMEPLPPQCS 1025

Query: 1028 PVADS--FQGSSVLSLSELPKAPLQ-----------NGLSIPLSSSESSSTRLSPPDVSA 1074
            P+        +S  S    P  PL             G+S      E  + ++S P+  A
Sbjct: 1026 PLLQHSLVPQNSPPSQCSPPALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECPA 1085

Query: 1075 L---LDISLPGPPED-ALSQGEPATHISDSIIEIAISSGQYGEGVPLSPAKLNGSDSSKS 1130
            L       LP P  D +     PA  + D              G+    A L+G D+  S
Sbjct: 1086 LEPSATSPLPSPMGDLSCPAPSPAPALDDF------------SGLGEDTAPLDGIDAPGS 1133

Query: 1131 LPSPSSSP 1138
             P P  +P
Sbjct: 1134 QPEPGQTP 1141



 Score = 54.3 bits (129), Expect = 7e-07
 Identities = 154/640 (24%), Positives = 216/640 (33%), Gaps = 173/640 (27%)

Query: 517  QDTGPCLEKTPAEGRDSPTREPGALPCACGQLPDLEDELSLLDPLPRYLKSCQDLIVPEQ 576
            Q T  C   +P E  D+PT EP AL  AC   P      S+    P           P Q
Sbjct: 364  QHTPVCSRFSPPEPGDTPTDEPDALYVACQGQPKGGHVTSMQPKEPG----------PLQ 413

Query: 577  CRCADTRPGSEQPPLGGAA---SPEVLAPVSKEAADLAPTGPSPRPGPGLLLDVCTKDLA 633
            C         E  PLG A     P++ AP+++E   L P   SP              L+
Sbjct: 414  C---------EAKPLGKAGVQLEPQLEAPLNEEMPLLPPPEESP--------------LS 450

Query: 634  DAPAEELQEKGSPAGPPPSQGQPAARPPKEVPASRLAQQLREEGWNLQTSESLTLAEVYL 693
              P E      SP  PPP +    + PP+E+PAS L + L                    
Sbjct: 451  PPPEE------SPTSPPP-EASRLSPPPEELPASPLPEALH------------------- 484

Query: 694  MMGKPSKLQLEYDWLGPGRQD----PRPGSLPTALHKQRLLSCLLKLISTEVNPKLALEA 749
             + +P    LE   L P  ++    P P S P +  ++  LS        E  P  ALE 
Sbjct: 485  -LSRP----LEESPLSPPPEESPLSPPPESSPFSPLEESPLS-----PPEESPPSPALE- 533

Query: 750  NTISTASVRPAQEEQSMTPPGKVVTVSSRSPRCPRNQASLRSSKTFPPSSAPCSSGLRNP 809
                   + P  E   ++PP         SP  P         +  P S  P +S L  P
Sbjct: 534  -----TPLSPPPEASPLSPP------FEESPLSP-------PPEELPTSPPPEASRLSPP 575

Query: 810  PRPLLVPGPSSTGSNDSDGGLFAVPTTLPPNSRHGKLFSPSKEAELTFRQHLNSISMQSD 869
            P       P S    +S       P + PP +   +LF P +E+ L+     + +S    
Sbjct: 576  PE----ESPMSPPPEES-------PMSPPPEA--SRLFPPFEESPLSPPPEESPLS---- 618

Query: 870  FFLPKPRKLRNRHLRKPLVVQRTLLPRPSENQSHNVCSFSILSNSSVTGRGSFRPIQSSL 929
               P P   R      P      + P P E+        S LS   V  R S  P +S L
Sbjct: 619  ---PPPEASR----LSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPL 671

Query: 930  TKAALSRPIVPKVLPPQATSHLASAIDLAATSAGILSGNPLPALDTEGLSGISPLSSDEV 989
            +      P  P   PP+A                               S +SP   D  
Sbjct: 672  SPPPEESPTSP---PPEA-------------------------------SRLSPPPEDSP 697

Query: 990  TGAISGQDSTGTHQDGDTLPTVG-GSDPFVSIPSRPEQEPVADSFQGSSVLSLSELPKAP 1048
            T     +DS  +    D+L ++     P + +P  P+  P ++         LS  P+ P
Sbjct: 698  TSP-PPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEG------PHLSPRPEEP 750

Query: 1049 -LQNGLSIPLSSSESSSTRLSP-PDVSALLDISLPGPPEDALSQGEPATHISDSIIEIAI 1106
             L      P  S ++    LSP P+   L  +    P E  LS      H+S    E+ +
Sbjct: 751  HLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAV----PEEPHLSPQAEGPHLSPQPEELHL 806

Query: 1107 S---SGQYGEGVPLSPAKLNGSDSSKSLP---SPSSSPQP 1140
            S      +   VP  P      + S   P    P  SP+P
Sbjct: 807  SPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRP 846



 Score = 52.0 bits (123), Expect = 4e-06
 Identities = 188/784 (23%), Positives = 259/784 (33%), Gaps = 160/784 (20%)

Query: 476  PPPAADALQSSGESSPESAPGEGAALSLSSPDAPDRPPPRH------------------- 516
            PPP    L    E SP S P E + LS    D+P  PPP                     
Sbjct: 664  PPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEES 723

Query: 517  -------------QDTGPCLEKTPAEGRDSPTREPGAL---------------PCACGQL 548
                         +  GP L   P E   SP  E   L               PC C  +
Sbjct: 724  PLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCA-V 782

Query: 549  PDLEDELSLLDPLPRYLKSCQDLIVPEQCRCADTRPGSEQPPLGGAASPEVLAPVSKEAA 608
            P+ E  LS     P      ++L +  Q       P  E+P L        L+P S+E  
Sbjct: 783  PE-EPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPC 841

Query: 609  DLAPTGPSPRPGPGLLLDVCTK-DLADAPAEELQEKGS-------PAGPPPSQ------- 653
                   SPRP    L     K  L+  P +  +E G        P  PPP +       
Sbjct: 842  ------LSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLL 895

Query: 654  GQPAARPPKEVPASRLAQQLREEGWNLQTSESLTLAEVYLMMGKPSKLQLEYDWLGPGRQ 713
            G+PA   P E P S L ++L      L  S            G+PS   L    + P   
Sbjct: 896  GEPALSEPGEPPLSPLPEEL-----PLSPS------------GEPS---LSPQLMPPDPL 935

Query: 714  DPRPGSLPTALHKQRLLSCLLKL-----ISTEVNPKLALEANTISTASVRPAQEEQSMTP 768
             P    + TA      LS L +L        + +P+  L A  + T  + P  E     P
Sbjct: 936  PPPLSPIITAA-APPALSPLGELEYPFGAKGDSDPESPLAAPILET-PISPPPEANCTDP 993

Query: 769  PGKVVTVSSRSPRCPRNQASLRSSKTFPPSSAPCSSGLRNPPRPLLVPGPSSTGSNDSDG 828
                  +   SP  P   AS    +  PP    CS        PLL        S  S  
Sbjct: 994  EPVPPMILPPSPGSPVGPASPILMEPLPPQ---CS--------PLLQHSLVPQNSPPSQC 1042

Query: 829  GLFAVPTTLP-PNSRHGKLFSPSKEAELTFRQHLNSISMQSDFFLPKPRKLRNRHLRKPL 887
               A+P ++P P S  GK+   S EAEL    H       S+   P         L  P+
Sbjct: 1043 SPPALPLSVPSPLSPIGKVVGVSDEAEL----HEMETEKVSEPECPALEPSATSPLPSPM 1098

Query: 888  VVQRTLLPRPSENQSHNVCSFSILSNSSVTGRGSFRPIQSSLTKAALSRPIVPKVLPPQA 947
                  L  P+ + +  +  FS L   +    G           A  S+P      P Q 
Sbjct: 1099 ----GDLSCPAPSPAPALDDFSGLGEDTAPLDG---------IDAPGSQP-----EPGQT 1140

Query: 948  TSHLASAIDLAATSAGILSGNPLPALDTEGLSGISPLSSDEVTGAISGQDSTGTHQD--- 1004
               LAS           L G+P+  LD E L+ ++P+         +GQ S    Q+   
Sbjct: 1141 PGSLASE----------LKGSPV-LLDPEELAPVTPMEVYPECKQTAGQGSPCEEQEEPR 1189

Query: 1005 ---GDTLPTVGGSDPFVSIPSRPEQEPVADSFQGSSVLSLSELPKA----PLQNGLSIPL 1057
                 T PT+  SD  V+  S   Q   + SF GS  L  S  P+      ++ G+S  +
Sbjct: 1190 APVAPTPPTLIKSD-IVNEISNLSQGDASASFPGSEPLLGSPDPEGGGSLSMELGVSTDV 1248

Query: 1058 SSSESSSTRLSPPDVSALLDISLPGPPEDALS----QGEPATHISD---SIIEIAISSGQ 1110
            S +    +     D     D SL      A+S    +GE     S    S I+   SS  
Sbjct: 1249 SPARDEGSLRLCTDSLPETDDSLLCDAGTAISGGKAEGEKGRRRSSPARSRIKQGRSSSF 1308

Query: 1111 YGEGVPLSPAKLNGSDSSKSLPSPSSSPQPHWIASPTHDPQWYPSDSTDSSLSSLFASFI 1170
             G   P   A          L S +SS +   +A     P     +  D ++ +    F 
Sbjct: 1309 PGRRRPRGGAHGGRGRGRARLKSTASSIETLVVADIDSSPSKEEEEEDDDTMQNTVVLFS 1368

Query: 1171 SPEK 1174
            + +K
Sbjct: 1369 NTDK 1372



 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 179/817 (21%), Positives = 263/817 (32%), Gaps = 142/817 (17%)

Query: 450  IQSGQGTARGQVKCPRSGAEGKGVGRPPPAADALQSSGESSPESAPGEGAALSLSSPDAP 509
            + S Q    G ++C        GV   P     L    E  P   P E + LS    ++P
Sbjct: 401  VTSMQPKEPGPLQCEAKPLGKAGVQLEPQLEAPLN---EEMPLLPPPEESPLSPPPEESP 457

Query: 510  DRPPPRHQDTGPCLEKTPAEGRDSPTREPGALPCACGQLPDLEDELSLLDPLPRYLKSCQ 569
              PPP      P  E+ PA    SP                L + L L  PL        
Sbjct: 458  TSPPPEASRLSPPPEELPA----SP----------------LPEALHLSRPLEE------ 491

Query: 570  DLIVPEQCRCADTRPGSEQPPLGGAASPEVLAPVSKEAADLAPTGPSPRPGPGLLLDVCT 629
                      +   P  E+ PL         +P+  E + L+P   SP P P L   +  
Sbjct: 492  ----------SPLSPPPEESPLSPPPESSPFSPL--EESPLSPPEESP-PSPALETPLSP 538

Query: 630  KDLADAPAEELQEKGSPAGPPPSQGQPAARPPKEVPASRLAQQLREEGWNLQTSESLTLA 689
               A   +   +E  SP  PPP +  P + PP+   ASRL+    E   +    ES    
Sbjct: 539  PPEASPLSPPFEE--SPLSPPPEE-LPTSPPPE---ASRLSPPPEESPMSPPPEES---- 588

Query: 690  EVYLMMGKPSKLQLEYDWLGPGRQDPRPGSLPTALHKQRLLSCLLKLISTEVNPKLALEA 749
                 M  P +    +         P P   P +                   P+ +  +
Sbjct: 589  ----PMSPPPEASRLFPPFEESPLSPPPEESPLS-----------------PPPEASRLS 627

Query: 750  NTISTASVRPAQEEQSMTPPGKV-----VTVSSRSPRCPRNQASLRSSKTFPPSSAPCSS 804
                 + + P  EE  M+PP +V     + V SR    P         +  P S  P +S
Sbjct: 628  PPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEAS 687

Query: 805  GLRNPPR--PLLVPGPSSTGSNDSDGGLFAVPTTLPPNSRHGKLFSPSKEAELTFRQHLN 862
             L  PP   P   P   S  S   +  L ++P    P      L    +E +L  R    
Sbjct: 688  RLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESP------LLPLPEEPQLCPRSEGP 741

Query: 863  SISMQSD--FFLPKPRKLRNRHLRKPLVVQRTLLPRPSENQSHNVCSFSILSNSSVTGRG 920
             +S + +     P+P +    HL  P   +  L P+P E     V     LS  +     
Sbjct: 742  HLSPRPEEPHLSPRPEE---PHL-SPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHL 797

Query: 921  SFRPIQSSLTKAALSR-----PIVPKVLPPQATSHLASAIDLAATSAGILSGNPLPALDT 975
            S +P +  L+           P  P + P    SHL+   +    S      +  P L+ 
Sbjct: 798  SPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEK 857

Query: 976  EGLSGISPLSSDEVTGAISGQDSTGTHQDGDTLPTVGGSDPFVSIPSRPEQEPVADSFQG 1035
              LS   P    E  G     +                  P    P  P   P+     G
Sbjct: 858  PPLSP-RPEKPPEEPGQCPAPEEL----------------PLFPPPGEPSLSPLL----G 896

Query: 1036 SSVLS-LSELPKAPLQNGLSIPLSSSESSSTRLSPPDVSALLDISLPGPPEDALSQGEPA 1094
               LS   E P +PL   L +  S   S S +L PPD        LP P    ++   P 
Sbjct: 897  EPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPD-------PLPPPLSPIITAAAPP 949

Query: 1095 THISDSIIEIAISSGQYGEGVPLSPAKLNGSDSSKSLPSPSSSPQPHWIASPTHDPQWYP 1154
                  + E+    G  G+  P SP       ++  L +P S P       P   P    
Sbjct: 950  A--LSPLGELEYPFGAKGDSDPESPL------AAPILETPISPPPEANCTDPEPVPPMIL 1001

Query: 1155 SDSTDSSL---SSLFASFISPEKSRKMLPTPIGTNSGTSLLGPSLLDGNSRDSFVSRSLA 1211
              S  S +   S +    + P+ S  +  + +  NS  S   P  L  +     V   L+
Sbjct: 1002 PPSPGSPVGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLS-----VPSPLS 1056

Query: 1212 DVAEVVDSQLVCMMNENSIDYISRFNDLAQELSIAEP 1248
             + +VV       ++E   + +S     A E S   P
Sbjct: 1057 PIGKVVGVSDEAELHEMETEKVSEPECPALEPSATSP 1093



 Score = 35.8 bits (81), Expect = 0.27
 Identities = 36/145 (24%), Positives = 53/145 (36%), Gaps = 8/145 (5%)

Query: 1014 SDPFVSIPSRPEQEPVADSFQGSSVLSLSELPKAPLQNGLSIPLSSSESSSTRLSPPDVS 1073
            SDPF  +P+ P+ +  + S      LS      +P+      P   S   S   S    +
Sbjct: 2405 SDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFA 2464

Query: 1074 ALLDISLPGPPEDALSQGEPA-THISDSIIEIAISSGQYGE-------GVPLSPAKLNGS 1125
             L     P PPE A   G  A T +       A+ +G  GE       G P +  +  G+
Sbjct: 2465 PLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQPPNFVRSPGT 2524

Query: 1126 DSSKSLPSPSSSPQPHWIASPTHDP 1150
             +    PSP     P  +  P+  P
Sbjct: 2525 GAFVGTPSPMRFTFPQAVGEPSLKP 2549



 Score = 31.6 bits (70), Expect = 5.0
 Identities = 22/73 (30%), Positives = 32/73 (43%), Gaps = 13/73 (17%)

Query: 602  PVSKEAADLAPTGPSPRPGPGLLLDVCTKDLADAPAEELQEKGSP------AGPPPSQGQ 655
            P  + +   +P  PSP   P       T+ L + P E L E   P      + P  ++ +
Sbjct: 4910 PPEEPSPPPSPLAPSPASPP-------TEPLVELPTEPLAEPPVPSPLPLASSPESARPK 4962

Query: 656  PAARPPKEVPASR 668
            P ARPP+E   SR
Sbjct: 4963 PRARPPEEGEDSR 4975



 Score = 31.2 bits (69), Expect = 6.6
 Identities = 57/232 (24%), Positives = 78/232 (33%), Gaps = 55/232 (23%)

Query: 457  ARGQVKCPRSGAEGKG--VGRPPPAADALQSSGESSPESAPGEGAALSLSSPDAPDRPPP 514
            +RGQ   P +G + K   VG PP        S  S P   PG     S  S D   RPPP
Sbjct: 2733 SRGQT--PFAGTQDKSSLVGLPP--------SKLSGPILGPG-----SFPSDDRLSRPPP 2777

Query: 515  RHQDTGPCLEKTPAEGRDSPTRE----PGALPCACGQLPDLEDELSLLDPLPRYLKSCQD 570
                +   +      G      +    PG+LP    Q    + + +      R+  S + 
Sbjct: 2778 PATPSSMDVNSRQLVGGSQAFYQRAPYPGSLPLQQQQQQLWQQQQATAATSMRFAMSARF 2837

Query: 571  LIVPEQCRCADTRPGSEQPPLGGAASPEVLAPVSKEAADLAPTGPSPRPGPGLLLDVCTK 630
                         P +  P LG  A    LA +S       P    P PGP         
Sbjct: 2838 -------------PSTPGPELGRQALGSPLAGISTRL----PGPGEPVPGPA-------- 2872

Query: 631  DLADAPAEELQ-----EKGSPAGPPPSQGQPAARPPKEVPASRLAQQLREEG 677
                 PA+ ++     +KG   G  P  GQ   + P+  P S    +L  EG
Sbjct: 2873 ----GPAQFIELRHNVQKGLGPGGTPFPGQGPPQRPRFYPVSEDPHRLAPEG 2920


>gi|167736355 mucin 4 isoform a [Homo sapiens]
          Length = 5284

 Score = 52.8 bits (125), Expect = 2e-06
 Identities = 110/502 (21%), Positives = 169/502 (33%), Gaps = 68/502 (13%)

Query: 743  PKLALEANTISTASVRPAQEEQSMTPPGKVVTVSSRSPR--CPRNQASLRSSKTFPP--- 797
            P+   E+ T  T SV P  + +++T PG   T S  SP    P++  ++ ++ TF P   
Sbjct: 643  PQTTQESQT--TRSVSPMTDTKTVTTPGSSFTASGHSPSEIVPQDAPTISAATTFAPAPT 700

Query: 798  -----SSAPCSSGLRNPPRPLLVPGPSSTGSNDSDGGL-FAVPTTLPPNSRHGK------ 845
                 + AP ++    P       GPS   S    G L  A      P    G+      
Sbjct: 701  GDGHTTQAPTTALQAAPSSHDATLGPSGGTSLSKTGALTLANSVVSTPGGPEGQWTSASA 760

Query: 846  LFSPSKEAELTFRQHLNSISMQSDFFLPKPRKLRNRHLRKPLVVQRTLLPRPSENQSHNV 905
              SP   A +T      S          +P    +R          T  P  S       
Sbjct: 761  STSPDTAAAMTHTHQAESTEASGQTQTSEPASSGSR-----TTSAGTATPSSSGASGTTP 815

Query: 906  CSFSILSNSSVTGRGSFRPIQSSLTKAALSRPIVPKVLPPQATSHLASAIDLAATSAGIL 965
                 +S S  T R S  P + S T  + +       L   + SH A  +     S+ I+
Sbjct: 816  SGSEGISTSGETTRFSSNPSRDSHTTQSTTE------LLSASASHGAIPVSTGMASS-IV 868

Query: 966  SGNPLPALDTEGLSG--------ISPLSSDEVTGAISGQ---DSTGTHQDGDTLPTVG-G 1013
             G   P L     +G         SP +S + T AIS       T T +  DT+      
Sbjct: 869  PGTFHPTLSEASTAGRPTGQSSPTSPSASPQETAAISRMAQTQRTRTSRGSDTISLASQA 928

Query: 1014 SDPFVSIPSRPEQ-------EPVADSFQGSSVLSLSELPKAPLQNGLSIPLSSSESSSTR 1066
            +D F ++P  P          P  ++   S   S      A + N   +P++ + S+ST 
Sbjct: 929  TDTFSTVPPTPPSITSTGLTSPQTETHTLSPSGSGKTFTTALISNATPLPVTYASSASTG 988

Query: 1067 LSPP-------DVSALLDISLPGPPEDALSQGE----PATHISDS-------IIEIAISS 1108
             + P        VS      LP     ++S G     P T  S         +   + SS
Sbjct: 989  HTTPLHVTDASSVSTGHATPLPVTSPSSVSTGHTTPLPVTDTSSESTGHVTPLPVTSFSS 1048

Query: 1109 GQYGEGVPLSPAKLNGSDSSKSLPSPSSSPQPHWIASPTHDPQWYPSDSTDSSLSSLFAS 1168
               G+  PL     + + +    P P +S         T  P    S ++    +SL  +
Sbjct: 1049 ASTGDSTPLPVTDTSSASTGHVTPLPVTSLSSASTGDTTPLPVTDTSSASTGHATSLPVT 1108

Query: 1169 FISPEKSRKMLPTPIGTNSGTS 1190
              S   +    P P+   S  S
Sbjct: 1109 DTSSVSTGHTTPLPVTDTSSAS 1130



 Score = 42.4 bits (98), Expect = 0.003
 Identities = 103/468 (22%), Positives = 158/468 (33%), Gaps = 55/468 (11%)

Query: 753  STASVRPAQEEQSMTPPGKVVT-----VSSRSPRCPRNQASLRSSKTFPPSSAPCSSGLR 807
            ST    P  E  +++P G   T     +S+ +P      +S  +  T P      SS   
Sbjct: 944  STGLTSPQTETHTLSPSGSGKTFTTALISNATPLPVTYASSASTGHTTPLHVTDASSVST 1003

Query: 808  NPPRPLLVPGPSSTGSNDSDGGLFAVPTTLPPNSRHGKL-------FSPSKEAELTFRQH 860
                PL V  PSS     S G    +P T   +   G +       FS +   + T    
Sbjct: 1004 GHATPLPVTSPSSV----STGHTTPLPVTDTSSESTGHVTPLPVTSFSSASTGDSTPLPV 1059

Query: 861  LNSISMQSDFFLPKPRKLRNRHLRKPLVVQRTLLP--RPSENQSHNVCSFSILSNSSV-T 917
             ++ S  +    P P       L        T LP    S   + +  S  +   SSV T
Sbjct: 1060 TDTSSASTGHVTPLPVT----SLSSASTGDTTPLPVTDTSSASTGHATSLPVTDTSSVST 1115

Query: 918  GRGSFRPI---QSSLTKAALSRPIVPKVLPPQATSHLASAIDLAATSAGILSGNPLPAL- 973
            G  +  P+    S+ T  A S P+        +T H        A+SA      PLP   
Sbjct: 1116 GHTTPLPVTDTSSASTGHATSLPVTDT--SSVSTGHTTPLHVTDASSASTGQATPLPVTS 1173

Query: 974  -------DTEGLSGISPLSSD--EVTGAISGQDSTGTHQDGDTLPTVGGSDPFVS-IPSR 1023
                   DT  L   SP S+     T  +    S+ +      LP    S        S 
Sbjct: 1174 LSSVSTGDTTPLPVTSPSSASTGHATPLLVTDTSSASTGHATPLPVTDASSVSTDHATSL 1233

Query: 1024 PEQEPVADSFQGSSVLSLSELPKAPLQNGLSIPLSSSESSSTRLSPPDVSALLDISLPGP 1083
            P   P A S   ++ L +++   A      S+ ++ + S ST  + P         LP  
Sbjct: 1234 PVTIPSAASTGHTTPLPVTDTSSASTGQATSLLVTDTSSVSTGDTTP---------LPVT 1284

Query: 1084 PEDALSQGEPAT-HISDSIIEIAISSGQYGEGVPLSPAKLNGSDSSKSLPSPSSSPQPHW 1142
               + S G     H++        SS   G   PL    L+ + +  ++P P +SP    
Sbjct: 1285 STSSASTGHVTPLHVTSP------SSASTGHATPLPVTSLSSASTGDTMPLPVTSPSSAS 1338

Query: 1143 IASPTHDPQWYPSDSTDSSLSSLFASFISPEKSRKMLPTPIGTNSGTS 1190
                T  P    S  +    + L  +  S   + +  P P+ + S  S
Sbjct: 1339 TGDTTPLPVTDASSVSTGHTTPLHVTDASSASTGQATPLPVTSLSSVS 1386



 Score = 42.4 bits (98), Expect = 0.003
 Identities = 104/464 (22%), Positives = 167/464 (35%), Gaps = 53/464 (11%)

Query: 743  PKLALEANTISTASVRP------AQEEQSMTPPGKVVTVSSRS-----PRCPRNQASLRS 791
            P L  +A+++ST    P      +      T P  V   SS S     P    + +S+ +
Sbjct: 3632 PLLVTDASSVSTGHATPLPVTDASSASTGDTTPLPVTDTSSASTGQATPLPVTSLSSVST 3691

Query: 792  SKTFPPSSAPCSSGLRNPPRPLLVPGPSSTGSNDSDGGLFAVPTTLPPNSRHGKLFSPSK 851
              T P      SS       PL V  PSS  + D+      +P T P ++  G     + 
Sbjct: 3692 GDTTPLPVTDASSASTGHATPLPVTIPSSVSTGDT----MPLPVTSPSSASTGH----AT 3743

Query: 852  EAELTFRQHLNSISMQSDFFLP--KPRKLRNRHLRKPLVVQRTLLPRPSENQSHNVCSFS 909
               +T    L+S S      LP         RH   PL V  T      +     V   S
Sbjct: 3744 PLPVT---GLSSASTGDTTPLPVTDTSSASTRHAT-PLPVTDTSSASTDDTTRLPVTDVS 3799

Query: 910  ILSNSSVTGRGSFRPIQS-SLTKAALSRPIVPKVLPPQATSHLASAIDLAATSAGILSGN 968
                S+ TG  +  P+ S S      + P+        +T H  S    + +SA      
Sbjct: 3800 ----SASTGHATPLPVTSTSSASTGDTTPLPVTDTSSVSTGHATSLPVTSRSSASTGHAT 3855

Query: 969  PLPALDTEGLSG--ISPLSSDEVTGAISGQDSTGTHQDGDTLPTVGGSDPFVSIPSRPEQ 1026
            PLP  DT  +S    +PL     T ++S   +T       +  + G + P          
Sbjct: 3856 PLPVTDTSSVSTGHATPLPVTS-TSSVSTGHATPLPVTSPSSASTGHATPV--------- 3905

Query: 1027 EPVADSFQGSSVLSLSELPKAPLQNGLSIPLSSSESSSTRLSPPDVSALLDISLPGPPED 1086
             PV  +    S  S  +    P+ N  S  LS+  ++   ++ P  ++  D S   P  D
Sbjct: 3906 -PVTST----SSASTGDTTPLPVTNASS--LSTGHATPLHVTSPSSASRGDTSTL-PVTD 3957

Query: 1087 ALSQGEPATHISDSIIEIAISSGQYGEGVPLSPAKLNGSDSSKSLPSPSSSPQPHWIASP 1146
            A S    +T  +  +   ++SS   G+  PL     + + + ++ P P +S         
Sbjct: 3958 ASSA---STGHATPLPLTSLSSVSTGDTTPLPVTDTSSASTGQATPLPVTSLSSVSTGDT 4014

Query: 1147 THDPQWYPSDSTDSSLSSLFASFISPEKSRKMLPTPIGTNSGTS 1190
            T  P   PS ++    +SL  +  S   +    P P+ + S  S
Sbjct: 4015 TPLPVTIPSSASSGHTTSLPVTDASSVSTGHGTPLPVTSTSSAS 4058



 Score = 42.0 bits (97), Expect = 0.004
 Identities = 108/531 (20%), Positives = 184/531 (34%), Gaps = 89/531 (16%)

Query: 742  NPKLALEANTISTASVRPAQEEQSMTPPGKVVTVSSRS-PRCPRNQASLRSSKTFPPSSA 800
            +P L  +A++ ST    P      +T    V T  +   P    + AS   +   P +  
Sbjct: 1743 SPLLVTDASSASTGQATPLP----VTDTSSVSTAHATPLPVTGLSSASTDDTTRLPVTDV 1798

Query: 801  PCSSGLRNPPRPLLVPGPSSTG----------SNDSDGGLFAVPTTLPPNSRHGKLFS-P 849
              +S  +  P P+  P  +STG          S+ S G   ++P T+P ++  G   S P
Sbjct: 1799 SSASTGQAIPLPVTSPSSASTGDTTPLPVTDASSASTGDTTSLPVTIPSSASSGHTTSLP 1858

Query: 850  SKEAELTFRQHLNSI------SMQSDFFLPKP---------------------------- 875
              +A      H  S+      S+ +    P P                            
Sbjct: 1859 VTDASSVSTGHATSLLVTDASSVSTGDTTPLPVTDTNSASTGDTTPLHVTDASSVSTGHA 1918

Query: 876  RKLRNRHLRKPLVVQRTLLP--RPSENQSHNVCSFSILSNSSV-TGRGSFRPI-QSSLTK 931
              L    L        T LP   PS   S +     +   SSV TG  +  P+  +S   
Sbjct: 1919 TSLPVTSLSSASTGDTTPLPVTSPSSASSGHTTPLPVTDASSVPTGHATSLPVTDASSVS 1978

Query: 932  AALSRPIVPKVLPPQATSHLAS--AIDLAATSAGILSGNPLPALDTEGLSGISPLSSDEV 989
               + P+        +T H       D ++ S G  +  P+ +L +      +PL   + 
Sbjct: 1979 TGHATPLPVTDASSVSTGHATPLPVTDTSSVSTGQATPLPVTSLSSASTGDTTPLPVTDT 2038

Query: 990  TGAISGQD------STGTHQDGDTLP---------TVGGSDPFVSIPSRPEQEPVADSFQ 1034
            + A +GQD      S  +   GDT P         + G + P +   +       A S  
Sbjct: 2039 SSASTGQDTPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDASSVSTGHATSLL 2098

Query: 1035 GSSVLSLSELPKAPLQNGLSIPLSSSESSSTRLSPPDVSALLDIS-LPGPPEDALSQGE- 1092
             +   S+S      L    +  LS+ +++   ++ P  ++  D + LP     ++S G  
Sbjct: 2099 VTDASSVSTGHATALHVTDASSLSTGDTTPLPVTSPSSASTGDTTPLPVTDTSSVSTGHA 2158

Query: 1093 ---PATHISD-------SIIEIAISSGQYGEGVPLSPAKLNGSDSSKSLPSPSSSPQPHW 1142
               P T  S        S+     SS   G   PL     + + + ++ P P +SP    
Sbjct: 2159 TSLPVTDTSSASTGHATSLPVTDTSSASTGHATPLPVTDTSSASTGQATPLPVTSPSS-- 2216

Query: 1143 IASPTHDPQWYPSDSTDSS---LSSLFASFISPEKSRKMLPTPIGTNSGTS 1190
             AS  H      +D++ +S    + L  + +S   +    P P+   S  S
Sbjct: 2217 -ASTGHAIPLLVTDTSSASTGQATPLPVTSLSSASTGDTTPLPVTDASSVS 2266



 Score = 40.8 bits (94), Expect = 0.008
 Identities = 57/266 (21%), Positives = 98/266 (36%), Gaps = 39/266 (14%)

Query: 947  ATSHLASAIDLAATSAGILSGNPLPALDTEGLS--GISPLSSDEVTGAISGQ------DS 998
            +T H  S +   A+S       PLP  DT   S    +PL   + +   +G        S
Sbjct: 1866 STGHATSLLVTDASSVSTGDTTPLPVTDTNSASTGDTTPLHVTDASSVSTGHATSLPVTS 1925

Query: 999  TGTHQDGDTLPTVGGSDPFVSIPSRPEQEPVADSFQGSSVLSLSELPKAPLQNGLSIPLS 1058
              +   GDT P              P   P + S   ++ L +++    P  +  S+P++
Sbjct: 1926 LSSASTGDTTPL-------------PVTSPSSASSGHTTPLPVTDASSVPTGHATSLPVT 1972

Query: 1059 SSESSSTRLSPP-------DVSALLDISLPGPPEDALSQGEPATHISDSIIEIAISSGQY 1111
             + S ST  + P        VS      LP     ++S G+     +  +   ++SS   
Sbjct: 1973 DASSVSTGHATPLPVTDASSVSTGHATPLPVTDTSSVSTGQ-----ATPLPVTSLSSAST 2027

Query: 1112 GEGVPLSPAKLNGSDSSKSLPSPSSSPQPHWIASPTHDPQWYPSDSTDSSLSSLF---AS 1168
            G+  PL     + + + +  P P +S         T  P   PS ++    + L    AS
Sbjct: 2028 GDTTPLPVTDTSSASTGQDTPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDAS 2087

Query: 1169 FISPEKSRKMLPT---PIGTNSGTSL 1191
             +S   +  +L T    + T   T+L
Sbjct: 2088 SVSTGHATSLLVTDASSVSTGHATAL 2113



 Score = 40.4 bits (93), Expect = 0.011
 Identities = 59/291 (20%), Positives = 112/291 (38%), Gaps = 26/291 (8%)

Query: 912  SNSSVTGRGSFRPIQSSLTKAALSRPIVPKVLPPQATSHLASAIDLAATS-AGILSGNPL 970
            ++S+ TG  +  P+  + + +      +P      A++  A+ + +  TS A I     L
Sbjct: 2822 TSSASTGHATSLPVTDTSSASTGHATPLPDTDTSSASTGHATLLPVTDTSSASIGHATSL 2881

Query: 971  PALDTEGLSG--ISPLSSDEVTGAISGQDSTGTHQDGDTLPTVGGSDPFVSIPSRPEQE- 1027
            P  DT  +S    +PL     + A +G  +     D  +  T   +   V+ PS      
Sbjct: 2882 PVTDTSSISTGHATPLHVTSPSSASTGHATPLPVTDTSSASTGHANPLHVTSPSSASTGH 2941

Query: 1028 ----PVADSFQGSS----VLSLSELPKAPLQNGLSIPLSSSESSSTRLSPPDVSALLDIS 1079
                PV D+   S+     L ++ L      +   +P++S  S+ST  + P         
Sbjct: 2942 ATPLPVTDTSSASTGHATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHTTP--------- 2992

Query: 1080 LPGPPEDALSQGEPATHISDSIIEIAISSGQYGEGVPLSPAKLNGSDSSKSLPSPSSSPQ 1139
            LP     + S G+     + ++   + SS   G+  PL     + + + ++ P P +S  
Sbjct: 2993 LPVTDTSSASTGQ-----ATALPVTSTSSASTGDTTPLPVTDTSSASTGQATPLPVTSLS 3047

Query: 1140 PHWIASPTHDPQWYPSDSTDSSLSSLFASFISPEKSRKMLPTPIGTNSGTS 1190
                   T  P   PS ++    + L  +  S   + +  P P+ + S  S
Sbjct: 3048 SVSTGDTTPLPVTSPSSASTGHATPLLVTDASSASTGQATPLPVTSLSSVS 3098



 Score = 40.0 bits (92), Expect = 0.014
 Identities = 65/309 (21%), Positives = 115/309 (37%), Gaps = 30/309 (9%)

Query: 912  SNSSVTGRGSFRPIQSSLTKAALSRPIVPKVLPPQA-TSHLASAIDLAATSAGILSGNPL 970
            ++S+ TG+ +  P+ S  + +      +P   P  A T H    +   A+SA      PL
Sbjct: 3030 TSSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDASSASTGQATPL 3089

Query: 971  PALDTEGLS--GISPLSSDEVTGAISGQDS------TGTHQDGDT--LPTVGGSDPFVS- 1019
            P      +S    +PL     + A +G  +      T +   GDT  LP    S  +   
Sbjct: 3090 PVTSLSSVSTGDTTPLPVTSPSSASTGHATSLPVTDTSSASTGDTTSLPVTDTSSAYTGD 3149

Query: 1020 IPSRPEQEPVADSFQGSSVLSLSELPKAPLQNGLSIPLSSSESSSTRLSPP-----DVSA 1074
              S P  +  + S   ++ L ++E       +   + ++ + S+ST  + P       SA
Sbjct: 3150 TTSLPVTDTSSSSTGDTTPLLVTETSSVSTGHATPLLVTDASSASTGHATPLHVTSPSSA 3209

Query: 1075 LLDISLPGPPED--ALSQGE----PATHISDS-------IIEIAISSGQYGEGVPLSPAK 1121
                + P P  D  ++S G     P T +S +       +    ISS   G+  PL    
Sbjct: 3210 STGDTTPVPVTDTSSVSTGHATPLPVTGLSSASTGDTTRLPVTDISSASTGQATPLPVTN 3269

Query: 1122 LNGSDSSKSLPSPSSSPQPHWIASPTHDPQWYPSDSTDSSLSSLFASFISPEKSRKMLPT 1181
             +   +  ++P P +SP        T  P    S ++    + +  +  S   +    P 
Sbjct: 3270 TSSVSTGDTMPLPVTSPSSASTGHATPLPVTSTSSASTGHATPVPVTSTSSASTGHTTPL 3329

Query: 1182 PIGTNSGTS 1190
            P+   S  S
Sbjct: 3330 PVTDTSSAS 3338



 Score = 39.3 bits (90), Expect = 0.024
 Identities = 58/313 (18%), Positives = 113/313 (36%), Gaps = 42/313 (13%)

Query: 912  SNSSVTGRGSFRPIQSSLTKAALSRPIVPKVLPPQATSHLASAI---DLAATSAGILSGN 968
            ++S+ TG  +  P+  + + +      +P   P  A++  A  +   D ++ S G  +  
Sbjct: 2182 TSSASTGHATPLPVTDTSSASTGQATPLPVTSPSSASTGHAIPLLVTDTSSASTGQATPL 2241

Query: 969  PLPALDTEGLSGISPLSSDEVTGAISGQ------DSTGTHQDGDTLPTVGGSDPFVSIPS 1022
            P+ +L +      +PL   + +   +G        S  +   GDT P             
Sbjct: 2242 PVTSLSSASTGDTTPLPVTDASSVSTGHATSLPVTSLSSVSTGDTTPL------------ 2289

Query: 1023 RPEQEPVADSFQGSSVLSLSELPKAPLQNGLSIPLSSSESSSTRLSPPDVSALLDISLPG 1082
             P   P + S   ++ L +++   A   +   +P++S  S+ST  + P         LP 
Sbjct: 2290 -PVTSPSSASTGHATPLHVTDASSASTGHATPLPVTSLSSASTGDTTP---------LPV 2339

Query: 1083 PPEDALSQGEPAT-HISDS----------IIEIAISSGQYGEGVPLSPAKLNGSDSSKSL 1131
                + S G     H++D+          +   + SS   G   PL     + + +  + 
Sbjct: 2340 TSPSSASTGHATPLHVTDASSVSTGDTTPLPVTSSSSASSGHTTPLPVTDASSASTGDTT 2399

Query: 1132 PSPSSSPQPHWIASPTHDPQWYPSDSTDSSLSSLFASFISPEKSRKMLPTPIGTNSGTSL 1191
            P P +          TH P    S ++    + L  + +S   +    P P+ + S  S 
Sbjct: 2400 PLPVTDTSSASTGHATHLPVTGLSSASTGDTTRLPVTNVSSASTGHATPLPVTSTSSAST 2459

Query: 1192 LGPSLLDGNSRDS 1204
               + L G    S
Sbjct: 2460 GDTTPLPGTDTSS 2472



 Score = 38.9 bits (89), Expect = 0.032
 Identities = 56/244 (22%), Positives = 96/244 (39%), Gaps = 22/244 (9%)

Query: 912  SNSSVTGRGSFRPIQSSLTKAALSRPIVPKVLPPQATSHLASAIDLAATSAGILSGN-PL 970
            ++S  TG  +  P+ S+ + +      +P   P  A++  A+ + + +TS+       PL
Sbjct: 3862 TSSVSTGHATPLPVTSTSSVSTGHATPLPVTSPSSASTGHATPVPVTSTSSASTGDTTPL 3921

Query: 971  PALDTEGLSG--ISPLSSDEVTGAISGQDSTGTHQDGDTLPTVGGSD-PFVSIPSRPEQE 1027
            P  +   LS    +PL     + A  G  ST    D  +  T   +  P  S+ S    +
Sbjct: 3922 PVTNASSLSTGHATPLHVTSPSSASRGDTSTLPVTDASSASTGHATPLPLTSLSSVSTGD 3981

Query: 1028 ----PVADSFQGS----------SVLSLSELPKAPLQNGLSIPLSSSESSSTRLSPPDVS 1073
                PV D+   S          S+ S+S     PL   ++IP S+S   +T L   D S
Sbjct: 3982 TTPLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLP--VTIPSSASSGHTTSLPVTDAS 4039

Query: 1074 ALLDISLPGPPEDALSQGEPATHISDSIIEIAISSGQYGEGVPLSPAKLNGSDSSKSLPS 1133
            ++   +  G P    S    +T  +  +     SS   G   PL     + + +  + P 
Sbjct: 4040 SVS--TGHGTPLPVTSTSSASTGDTTPLPVTDTSSASTGHATPLPVTDTSSASTGHATPL 4097

Query: 1134 PSSS 1137
            P +S
Sbjct: 4098 PVTS 4101



 Score = 38.5 bits (88), Expect = 0.041
 Identities = 63/325 (19%), Positives = 114/325 (35%), Gaps = 31/325 (9%)

Query: 897  PSENQSHNVCSFSILSNSSV-TGRGSFRPI-QSSLTKAALSRPIVPKVLPPQATSHLASA 954
            PS   S +     +   SSV TG  +  P+  +S      + P+        +T H    
Sbjct: 2710 PSSASSGHTTPLPVTDASSVSTGHATSLPVTDASSVSTGHATPLPVTDASSVSTGHATPL 2769

Query: 955  IDLAATSAGILSGNPLPALDTEGLS----------GISPLSSDEVTGAISGQDSTGTHQD 1004
               + +S       PLP  DT   S           +S +S+ + T       S+ +   
Sbjct: 2770 PLTSLSSVSTGDTTPLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLPVTDTSSASTGH 2829

Query: 1005 GDTLPTVGGSDPFVSIPSR-PEQEPVADSFQGSSVLSLSELPKAPLQNGLSIPLSSSESS 1063
              +LP    S       +  P+ +  + S   +++L +++   A + +  S+P++ + S 
Sbjct: 2830 ATSLPVTDTSSASTGHATPLPDTDTSSASTGHATLLPVTDTSSASIGHATSLPVTDTSSI 2889

Query: 1064 STRLSPP-----DVSALLDISLPGPPEDALSQG----------EPATHISDSIIEIAI-- 1106
            ST  + P       SA    + P P  D  S             P++  +     + +  
Sbjct: 2890 STGHATPLHVTSPSSASTGHATPLPVTDTSSASTGHANPLHVTSPSSASTGHATPLPVTD 2949

Query: 1107 -SSGQYGEGVPLSPAKLNGSDSSKSLPSPSSSPQPHWIASPTHDPQWYPSDSTDSSLSSL 1165
             SS   G   PL    L+   +  + P P +SP        T  P    S ++    ++L
Sbjct: 2950 TSSASTGHATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHTTPLPVTDTSSASTGQATAL 3009

Query: 1166 FASFISPEKSRKMLPTPIGTNSGTS 1190
              +  S   +    P P+   S  S
Sbjct: 3010 PVTSTSSASTGDTTPLPVTDTSSAS 3034



 Score = 38.1 bits (87), Expect = 0.054
 Identities = 98/478 (20%), Positives = 162/478 (33%), Gaps = 76/478 (15%)

Query: 745  LALEANTISTASVRPAQ-EEQSMTPPGKVVTVSSRSPRCPRNQASLRSSKTFPPSSAPCS 803
            L  + +++ST    P      S    G V  +   SP    + AS   +   P +S   +
Sbjct: 1474 LVTDTSSVSTGDTTPLPVTSTSSASTGHVTPLHVTSP----SSASTGHATPLPVTSLSSA 1529

Query: 804  SGLRNPPRPLLVPGPSSTG----------SNDSDGGLFAVPTTLPPNSRHGKLFS-PSKE 852
            S     P P+  P  +STG          S+ S G    +P T P ++  G     P  +
Sbjct: 1530 STGDTMPLPVTSPSSASTGDTTPLPVTDASSVSTGHTTPLPVTSPSSASTGHTTPLPVTD 1589

Query: 853  AELTFRQHLNSISMQSDFFLPKPRKLRNRHLRKPLVVQRTLLPRPSENQSHNVCSFSILS 912
                 +     + + S      P      H   PL V  T      +     V + S LS
Sbjct: 1590 TSSASKGDTTPLPVTS------PSSASTGHTT-PLPVTDTSSASTGDTTPLPVTNASSLS 1642

Query: 913  NSSVTGRGSFRPIQSSLTKAALSRPIVPKVLPPQATSHLASAIDLAATSAGILSGNPLPA 972
                T      P+  +   +A +    P  LP  +TS         + S G  +  P+  
Sbjct: 1643 TGHAT------PLHVTSPSSASTGHATP--LPVTSTS---------SASTGHATPLPVTG 1685

Query: 973  LDTEGLSGISPLSSDEVTGAISGQ------DSTGTHQDGDTLPTVGGSDPFVSIPSRPEQ 1026
            L +      + L   +V+ A +GQ       S  +   GDT P              P  
Sbjct: 1686 LSSATTDDTTRLPVTDVSSASTGQATPLPVTSLSSVSTGDTTPL-------------PVT 1732

Query: 1027 EPVADSFQGSSVLSLSELPKAPLQNGLSIPLSSSESSSTRLSPPDVSALLDISLPGPPED 1086
             P + S   +S L +++   A       +P++ + S ST  + P             P  
Sbjct: 1733 SPSSASTGHASPLLVTDASSASTGQATPLPVTDTSSVSTAHATP------------LPVT 1780

Query: 1087 ALSQGEPATHISDSIIEIAISSGQYGEGVPLSPAKLNGSDSSKSLPSPSSSPQPHWIASP 1146
             LS    +T  +  +    +SS   G+ +PL     + + +  + P P +          
Sbjct: 1781 GLSSA--STDDTTRLPVTDVSSASTGQAIPLPVTSPSSASTGDTTPLPVTDASSASTGDT 1838

Query: 1147 THDPQWYPSDSTDSSLSSL---FASFISPEKSRKMLPTPIGTNSGTSLLGPSLLDGNS 1201
            T  P   PS ++    +SL    AS +S   +  +L T   + S        + D NS
Sbjct: 1839 TSLPVTIPSSASSGHTTSLPVTDASSVSTGHATSLLVTDASSVSTGDTTPLPVTDTNS 1896



 Score = 37.0 bits (84), Expect = 0.12
 Identities = 99/492 (20%), Positives = 161/492 (32%), Gaps = 50/492 (10%)

Query: 747  LEANTISTASVRPAQEEQSMTPPGKVVTVSSRSPRCPRNQASLRSSKTFPPSSAPCSSGL 806
            L     S+AS   A      +P       ++  P    + AS   +   P +S    S  
Sbjct: 2913 LPVTDTSSASTGHANPLHVTSPSSASTGHATPLPVTDTSSASTGHATPLPVTSLSSVSTG 2972

Query: 807  RNPPRPLLVPGPSSTG----------SNDSDGGLFAVPTTLPPNSRHGKLF--------- 847
               P P+  P  +STG          S+ S G   A+P T   ++  G            
Sbjct: 2973 DTTPLPVTSPSSASTGHTTPLPVTDTSSASTGQATALPVTSTSSASTGDTTPLPVTDTSS 3032

Query: 848  SPSKEAELTFRQHLNSISMQSDFFLP--KPRKLRNRHLRKPLVVQRTLLPRPSENQSHNV 905
            + + +A       L+S+S      LP   P      H   PL+V         +     V
Sbjct: 3033 ASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHAT-PLLVTDASSASTGQATPLPV 3091

Query: 906  CSFSILSNSSVTGRGSFRPIQSSLTKAALSRPIVPKVLPPQATSHLASAIDLAATSAGIL 965
             S S +S    T      P  +S T  A S P+          +      D ++   G  
Sbjct: 3092 TSLSSVSTGDTTPLPVTSPSSAS-TGHATSLPVTDTSSASTGDTTSLPVTDTSSAYTGDT 3150

Query: 966  SGNPLPALDTEGLSGISPLSSDEVTGAISGQDSTGTHQDGDTLPTVGGSDPFVSIPSRPE 1025
            +  P+    +      +PL   E +   +G  +     D  +  T   +   V+ PS   
Sbjct: 3151 TSLPVTDTSSSSTGDTTPLLVTETSSVSTGHATPLLVTDASSASTGHATPLHVTSPSSAS 3210

Query: 1026 QE-----PVADSFQGSS----VLSLSELPKAPLQNGLSIPLSSSESSSTRLSPP------ 1070
                   PV D+   S+     L ++ L  A   +   +P++   S+ST  + P      
Sbjct: 3211 TGDTTPVPVTDTSSVSTGHATPLPVTGLSSASTGDTTRLPVTDISSASTGQATPLPVTNT 3270

Query: 1071 -DVSALLDISLPGPPEDALSQGE----PATHISDS-------IIEIAISSGQYGEGVPLS 1118
              VS    + LP     + S G     P T  S +       +   + SS   G   PL 
Sbjct: 3271 SSVSTGDTMPLPVTSPSSASTGHATPLPVTSTSSASTGHATPVPVTSTSSASTGHTTPLP 3330

Query: 1119 PAKLNGSDSSKSLPSPSSSPQPHWIASPTHDPQWYPSDSTDSSLSSLFASFISPEKSRKM 1178
                + + +  + P P +SP        T      PS ++    S+L  +  S   +   
Sbjct: 3331 VTDTSSASTGDTTPLPVTSPSSASTGHTTPLHVTIPSSASTGDTSTLPVTGASSASTGHA 3390

Query: 1179 LPTPIGTNSGTS 1190
             P P+   S  S
Sbjct: 3391 TPLPVTDTSSVS 3402



 Score = 36.2 bits (82), Expect = 0.20
 Identities = 102/460 (22%), Positives = 160/460 (34%), Gaps = 63/460 (13%)

Query: 772  VVTVSSRS-----PRCPRNQASLRSSKTFPPSSAPCSSGLRNPPRPLLVPGPSSTGSNDS 826
            V  VSS S     P    + +S  +  T P      SS       PLLV   SS  + D+
Sbjct: 2435 VTNVSSASTGHATPLPVTSTSSASTGDTTPLPGTDTSSVSTGHTTPLLVTDASSVSTGDT 2494

Query: 827  DGGLFAVPTTLPPNSRHGKLFSPSKEAELTFRQHLNSISMQSDFFLP--KPRKLRNRHLR 884
                  +P T P ++  G   +P    +        S S      LP      L  RH  
Sbjct: 2495 T----RLPVTSPSSASTGHT-TPLPVTDTP------SASTGDTTPLPVTNASSLSTRHAT 2543

Query: 885  KPLVVQRTLLPRPSENQSHNVCSFSILSNSSVTGRGSFRPIQSSLTKAALSRPIVPKVLP 944
               V        PS   + +  S  + +++S    G   P+  + T +A +    P  + 
Sbjct: 2544 SLHVTS------PSSASTGHATSLPV-TDTSAASTGHATPLPVTSTSSASTGDTTPLPVT 2596

Query: 945  PQATSHLASAIDLAAT---SAGILSGNPLPALDTEGLSG--ISPLSSDEVTGAISGQDST 999
               ++    A  L  T   SA      PLP  DT   S    +PL     T ++S   +T
Sbjct: 2597 DTYSASTGQATPLPVTDTSSASTGDTTPLPVTDTSSASTGHATPLPVTN-TSSVSTGHAT 2655

Query: 1000 GTHQDGDTLPTVGGSDPFVSIPSRPEQEPVADSFQGSS--VLSLSELPKAPLQNG----- 1052
              H    +  + G + P           PV D+   S+    SL     + +  G     
Sbjct: 2656 PLHVTSPSSASTGHTTPL----------PVTDASSVSTGHATSLPVTDASSVFTGHATSL 2705

Query: 1053 -LSIPLSSSESSSTRLSPPDVSALLD---ISLPGPPEDALSQGE----PATHISD----- 1099
             ++IP S+S   +T L   D S++      SLP     ++S G     P T  S      
Sbjct: 2706 PVTIPSSASSGHTTPLPVTDASSVSTGHATSLPVTDASSVSTGHATPLPVTDASSVSTGH 2765

Query: 1100 --SIIEIAISSGQYGEGVPLSPAKLNGSDSSKSLPSPSSSPQPHWIASPTHDPQWYPSDS 1157
               +   ++SS   G+  PL     + + + ++ P P +S         T  P    S +
Sbjct: 2766 ATPLPLTSLSSVSTGDTTPLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLPVTDTSSA 2825

Query: 1158 TDSSLSSLFASFISPEKSRKMLPTPIGTNSGTSLLGPSLL 1197
            +    +SL  +  S   +    P P    S  S    +LL
Sbjct: 2826 STGHATSLPVTDTSSASTGHATPLPDTDTSSASTGHATLL 2865



 Score = 35.4 bits (80), Expect = 0.35
 Identities = 67/314 (21%), Positives = 109/314 (34%), Gaps = 73/314 (23%)

Query: 890  QRTLLPR--PSENQSHNVCSFSILSNSSVTGRGSFRPIQSSLTKAALSRPIVPKVLPPQA 947
            Q T LP   PS + S +     + S SSV+  G   P+  +   +A +  + P  +   +
Sbjct: 3565 QATPLPVTIPSSSSSGHTTPLPVTSTSSVS-TGHVTPLHVTSPSSASTGHVTPLPVTSTS 3623

Query: 948  TSHLASAIDLAATSAGILS---GNPLPALDTEGLSGISPLSSDEVTGAISGQDSTGTHQD 1004
            ++    A  L  T A  +S     PLP  D    S                         
Sbjct: 3624 SASTGHATPLLVTDASSVSTGHATPLPVTDASSAS------------------------T 3659

Query: 1005 GDTLPTVGGSDPFVSIPSRPEQEPVADSFQGSS----VLSLSELPKAPLQNGLSIPLSSS 1060
            GDT P                  PV D+   S+     L ++ L      +   +P++ +
Sbjct: 3660 GDTTPL-----------------PVTDTSSASTGQATPLPVTSLSSVSTGDTTPLPVTDA 3702

Query: 1061 ESSSTRLSPPDVSALLDISLPGPPEDALSQGEPATHISDSIIEIAISSGQYGEGVPLSPA 1120
             S+ST  + P     L +++P       +   P T         + SS   G   PL   
Sbjct: 3703 SSASTGHATP-----LPVTIPSSVSTGDTMPLPVT---------SPSSASTGHATPLPVT 3748

Query: 1121 KLNGSDSSKSLPSP----SSSPQPHWIASPTHDPQWYPSDSTDSSLSSLFASFISPEKSR 1176
             L+ + +  + P P    SS+   H    P  D     S STD + + L  + +S   + 
Sbjct: 3749 GLSSASTGDTTPLPVTDTSSASTRHATPLPVTDTS---SASTDDT-TRLPVTDVSSASTG 3804

Query: 1177 KMLPTPIGTNSGTS 1190
               P P+ + S  S
Sbjct: 3805 HATPLPVTSTSSAS 3818



 Score = 34.3 bits (77), Expect = 0.78
 Identities = 62/312 (19%), Positives = 105/312 (33%), Gaps = 32/312 (10%)

Query: 911  LSNSSVTGRGSFRPIQSSLTKAALSRPIVPKVLPPQATSHLASAIDLAATSAGILSGN-- 968
            ++++S    G   P+  +   +A +    P  +   +++     + L  TS    S    
Sbjct: 1283 VTSTSSASTGHVTPLHVTSPSSASTGHATPLPVTSLSSASTGDTMPLPVTSPSSASTGDT 1342

Query: 969  -PLPALDTEGLSG--ISPLSSDEVTGAISGQ------DSTGTHQDGDTLP---------T 1010
             PLP  D   +S    +PL   + + A +GQ       S  +   GDT P         +
Sbjct: 1343 TPLPVTDASSVSTGHTTPLHVTDASSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSAS 1402

Query: 1011 VGGSDPFV----SIPSRPEQEPV----ADSFQGSSVLSLSELPKAPLQNGLSIPLSSSES 1062
             G + P +    S  S     P+    A S       SL     +    G + PL  +++
Sbjct: 1403 TGHATPLLVTDTSSASTGHATPLPVTDASSVSTDHATSLPVTIPSAASTGHTTPLPVTDT 1462

Query: 1063 SSTRLSPPDVSALLDISLPGP----PEDALSQGEPATHISDSIIEIAISSGQYGEGVPLS 1118
            SS          + D S        P    S    +T     +   + SS   G   PL 
Sbjct: 1463 SSASTGQATSLLVTDTSSVSTGDTTPLPVTSTSSASTGHVTPLHVTSPSSASTGHATPLP 1522

Query: 1119 PAKLNGSDSSKSLPSPSSSPQPHWIASPTHDPQWYPSDSTDSSLSSLFASFISPEKSRKM 1178
               L+ + +  ++P P +SP        T  P    S  +    + L  +  S   +   
Sbjct: 1523 VTSLSSASTGDTMPLPVTSPSSASTGDTTPLPVTDASSVSTGHTTPLPVTSPSSASTGHT 1582

Query: 1179 LPTPIGTNSGTS 1190
             P P+   S  S
Sbjct: 1583 TPLPVTDTSSAS 1594



 Score = 34.3 bits (77), Expect = 0.78
 Identities = 58/275 (21%), Positives = 93/275 (33%), Gaps = 43/275 (15%)

Query: 897  PSENQSHNVCSFSILSNSSVTGRGSFRPIQSSLTKAALSRPIVPKVLPPQATSHLASAID 956
            PS   + +     +   SSV+  G   P+  + + +A S    P  +   +++       
Sbjct: 2342 PSSASTGHATPLHVTDASSVS-TGDTTPLPVTSSSSASSGHTTPLPVTDASSASTGDTTP 2400

Query: 957  LAATSAGILSGNPLPALDTEGLSGISP-----LSSDEVTGAISGQ------DSTGTHQDG 1005
            L  T     S      L   GLS  S      L    V+ A +G        ST +   G
Sbjct: 2401 LPVTDTSSASTGHATHLPVTGLSSASTGDTTRLPVTNVSSASTGHATPLPVTSTSSASTG 2460

Query: 1006 DTLPTVGGSDPFVSIPSR-------------------PEQEPVADSFQGSSVLSLSELPK 1046
            DT P  G     VS                       P   P + S   ++ L +++ P 
Sbjct: 2461 DTTPLPGTDTSSVSTGHTTPLLVTDASSVSTGDTTRLPVTSPSSASTGHTTPLPVTDTPS 2520

Query: 1047 APLQNGLSIPLSSSESSSTR-------LSPPDVSALLDISLPGPPEDALSQGEPATHISD 1099
            A   +   +P++++ S STR        SP   S     SLP     A S G      + 
Sbjct: 2521 ASTGDTTPLPVTNASSLSTRHATSLHVTSPSSASTGHATSLPVTDTSAASTGH-----AT 2575

Query: 1100 SIIEIAISSGQYGEGVPLSPAKLNGSDSSKSLPSP 1134
             +   + SS   G+  PL       + + ++ P P
Sbjct: 2576 PLPVTSTSSASTGDTTPLPVTDTYSASTGQATPLP 2610



 Score = 33.9 bits (76), Expect = 1.0
 Identities = 52/249 (20%), Positives = 89/249 (35%), Gaps = 29/249 (11%)

Query: 947  ATSHLASAIDLAATSAGILSGNPLPALDTEGLSG--ISPLSSDEVTGAISGQDSTGTHQD 1004
            +T H  S      +SA       LP  DT   S    +PL   + + A +GQ +T     
Sbjct: 2154 STGHATSLPVTDTSSASTGHATSLPVTDTSSASTGHATPLPVTDTSSASTGQ-ATPLPVT 2212

Query: 1005 GDTLPTVGGSDPFVSIPSRPEQEPVADSFQGSSVLSLSELPKAPLQNGLSIPLSSSESSS 1064
              +  + G + P +   +       A     +S+ S S     PL    +  +S+  ++S
Sbjct: 2213 SPSSASTGHAIPLLVTDTSSASTGQATPLPVTSLSSASTGDTTPLPVTDASSVSTGHATS 2272

Query: 1065 ---TRLSPPDVSALLDISLPGPPEDALSQGEPATHISDSIIEIAISSGQYGEGVPLSPAK 1121
               T LS         + +  P   +     P  H++D+      SS   G   PL    
Sbjct: 2273 LPVTSLSSVSTGDTTPLPVTSPSSASTGHATPL-HVTDA------SSASTGHATPLPVTS 2325

Query: 1122 LNGSDSSKSLPSPSSSPQPHWIASPTHDPQWYPSDSTDSSLSSLFASFISPEKSRKMLPT 1181
            L+ + +  + P P +SP     AS  H    + +D++  S                  P 
Sbjct: 2326 LSSASTGDTTPLPVTSPSS---ASTGHATPLHVTDASSVSTGDT-------------TPL 2369

Query: 1182 PIGTNSGTS 1190
            P+ ++S  S
Sbjct: 2370 PVTSSSSAS 2378



 Score = 33.9 bits (76), Expect = 1.0
 Identities = 63/328 (19%), Positives = 115/328 (35%), Gaps = 48/328 (14%)

Query: 911  LSNSSVTGRGSFRPIQSSLTKAALSRPIVPKVLPPQATSHLASAIDLAATSAGILSGN-- 968
            ++N+S    G   P+  +   +A +    P  +   +++    A  +  TS    S    
Sbjct: 3267 VTNTSSVSTGDTMPLPVTSPSSASTGHATPLPVTSTSSASTGHATPVPVTSTSSASTGHT 3326

Query: 969  -PLPALDTEGLS--GISPLSSDEVTGAISGQD--------STGTHQDGDTLPTVGGSDPF 1017
             PLP  DT   S    +PL     + A +G          S+ +  D  TLP  G S   
Sbjct: 3327 TPLPVTDTSSASTGDTTPLPVTSPSSASTGHTTPLHVTIPSSASTGDTSTLPVTGASSAS 3386

Query: 1018 VSIPSR-PEQEPVADSFQGSSVLSLSELPKAPLQNGLSIPLSSSESSST-RLSPPDVSAL 1075
                +  P  +  + S   ++ L ++ L      +   +P++ + S+ST + +P  V++L
Sbjct: 3387 TGHATPLPVTDTSSVSTGHATPLPVTSLSSVSTGDTTPLPVTDASSASTGQATPLPVTSL 3446

Query: 1076 LDIS----------------------LPGPPEDALSQGE----PATHISDS-------II 1102
              +S                      LP     + S G+    P T  S +       + 
Sbjct: 3447 SSVSTGDTTPLLVTDASSVSTGHATPLPVTDTSSASTGDTTRLPVTDTSSASTGQATPLP 3506

Query: 1103 EIAISSGQYGEGVPLSPAKLNGSDSSKSLPSPSSSPQPHWIASPTHDPQWYPSDSTDSSL 1162
              ++SS   G+  PL     +   +  + P P +          T  P    S ++    
Sbjct: 3507 VTSLSSVSTGDTTPLLVTDASSVSTGHATPLPVTDTSSASTGDTTRLPVTDTSSASTGQA 3566

Query: 1163 SSLFASFISPEKSRKMLPTPIGTNSGTS 1190
            + L  +  S   S    P P+ + S  S
Sbjct: 3567 TPLPVTIPSSSSSGHTTPLPVTSTSSVS 3594


>gi|91982772 mucin 17 [Homo sapiens]
          Length = 4493

 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 140/704 (19%), Positives = 240/704 (34%), Gaps = 97/704 (13%)

Query: 485  SSGESSPESAPGEGAALSLSSPDAP----------------DRPPPRHQDTGPCLEKTPA 528
            S G S P S PGEG+    S PD+                 D   P    T      T A
Sbjct: 909  SEGTSMPTSTPGEGSTPLTSMPDSTTPVVSSEARTLSATPVDTSTPVTTSTEATSSPTTA 968

Query: 529  EGRDSPTREPGALPCACGQLPDLEDELSLLDPLPRYLKSCQDLIVPEQCRCADTRPGSEQ 588
            EG   PT  P       G  P     +S              L+   +     T P    
Sbjct: 969  EGTSIPTSTPSE-----GTTPLTSTPVS------------HTLVANSEASTLSTTPVDSN 1011

Query: 589  PPL---GGAASPEVLAPVSKEAADLAPTGPSPRPGPGLLLDVCTKDLADAPAEELQEKGS 645
             PL     A+SP    P + E   +  + PS    P   + V T  +A +    L    +
Sbjct: 1012 TPLTTSTEASSP----PPTAEGTSMPTSTPSEGSTPLTRMPVSTTMVASSETSTLSTTPA 1067

Query: 646  PAGPPPSQGQPAARPPKEVPASRLAQQLREEGWNLQTSESLTL-----AEVYLMMGKPSK 700
                P +    A+        + +      EG    TS  ++      +E   +   P  
Sbjct: 1068 DTSTPVTTYSQASSSSTTADGTSMPTSTYSEGSTPLTSVPVSTRLVVSSEASTLSTTPVD 1127

Query: 701  LQLEYDWLGPGRQDPRPG---SLPTALHKQRLLSCLLKLISTEVNPKLALEANTISTASV 757
              +           P      S+PT+   +         +ST +   ++ EANT+ST  V
Sbjct: 1128 TSIPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTL--VVSSEANTLSTTPV 1185

Query: 758  ----RPAQEEQSMTPPGKVVTVSSRSPRCPRNQASLRSSKTFPPSSAPCSSGLRNPPRPL 813
                + A   ++ +PP     V+S     P  +++  +S     +    S        P+
Sbjct: 1186 DSKTQVATSTEASSPP-PTAEVTSMPTSTPGERSTPLTSMPVRHTPVASSEASTLSTSPV 1244

Query: 814  LVPGPSSTGSNDSDGGLFAVPTTLPPN-SRHGKLFSPSKEAELTFRQHLNSISMQSDFFL 872
                P +T +  S     A  T+LP + +  G     S     T        S ++   L
Sbjct: 1245 DTSTPVTTSAETSSSPTTAEGTSLPTSTTSEGSTLLTSIPVSTTL-----VTSPEASTLL 1299

Query: 873  PKPRKLRNRHLRKPLVVQRTL--LPRPSENQSHNVCSFSILSNSSVTGRGSFRPIQSSLT 930
              P   +      P+V    +   P P+E  S    ++S        GR     I  + T
Sbjct: 1300 TTPVDTKG-----PVVTSNEVSSSPTPAEGTSMPTSTYS-------EGRTPLTSIPVNTT 1347

Query: 931  KAALSRPIVPKVLPPQATSHLASAIDLAATSAGILSGNPLPALDTEGLSGISPLSSDEV- 989
              A S   +    P   ++ + ++ + A +S     G  +P  ++    G +PL+S  V 
Sbjct: 1348 LVASSAISILSTTPVDNSTPVTTSTE-ACSSPTTSEGTSMP--NSNPSEGTTPLTSIPVS 1404

Query: 990  -TGAISGQDSTGTHQDGDTLPTVGGSDPFVSIPSRPEQEPVADSFQGSSVLSLSELPKAP 1048
             T  +S + ST +    DT      S    S P+  E   +  S        L  +P + 
Sbjct: 1405 TTPVVSSEASTLSATPVDTSTPGTTSAEATSSPTTAEGISIPTSTPSEGKTPLKSIPVS- 1463

Query: 1049 LQNGLSIPLSSSESSSTRLSP-----PDVSALLDISLPGPPEDALSQGEPATHISDSIIE 1103
                 + P+++SE+S+   +P     P V++    S P P E         +  S ++  
Sbjct: 1464 -----NTPVANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIAISTPSEGSTALTS 1518

Query: 1104 IAISSGQYGEGVPLSPAKLNGSDSSKSLPSPSSSPQPHWIASPT 1147
            I +S+        ++ +++N   ++ ++ S   +      +SPT
Sbjct: 1519 IPVST------TTVASSEINSLSTTPAVTSTPVTTYSQASSSPT 1556



 Score = 49.7 bits (117), Expect = 2e-05
 Identities = 150/721 (20%), Positives = 248/721 (34%), Gaps = 101/721 (14%)

Query: 499  AALSLSSPDAPDRPPPRHQDTGPCLEKTPAEGRDSPTREPGALPCACGQLPDLEDELSLL 558
            +A+S  S    D   P    T      T +EG   PT  PG        +PD        
Sbjct: 880  SAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPGEGSTPLTSMPDSTTP---- 935

Query: 559  DPLPRYLKSCQDLIVPEQCRCADTRPGSEQPPLGGAASPEVLAPVSKEAADLAPTGPSPR 618
                         +V  + R     P     P+   ++    +P + E   +  + PS  
Sbjct: 936  -------------VVSSEARTLSATPVDTSTPV-TTSTEATSSPTTAEGTSIPTSTPSEG 981

Query: 619  PGPGLLLDVCTKDLADAPAEELQEKGSPAGPPPSQGQPAARPPKEVPASRLAQQLREEGW 678
              P     V    +A++ A  L      +  P +    A+ PP     + +      EG 
Sbjct: 982  TTPLTSTPVSHTLVANSEASTLSTTPVDSNTPLTTSTEASSPPPTAEGTSMPTSTPSEGS 1041

Query: 679  N-----------LQTSESLTLAEVYLMMGKPSKLQLEYDWLGPGRQDPRPGSLPTALHKQ 727
                        + +SE+ TL+        P      Y             S+PT+ + +
Sbjct: 1042 TPLTRMPVSTTMVASSETSTLSTTPADTSTP---VTTYSQASSSSTTADGTSMPTSTYSE 1098

Query: 728  RLLSCLLKLISTEVNPKLALEANTISTASVRPAQEEQSMTPPGKVVTVSSRSPRCPRNQA 787
               S  L  +       ++ EA+T+ST  V         + P    T +S SP      A
Sbjct: 1099 G--STPLTSVPVSTRLVVSSEASTLSTTPV-------DTSIPVTTSTEASSSP----TTA 1145

Query: 788  SLRSSKTFPPSSAPCSSGLRNPPRPLLVPGPSSTGSNDSDGGLFAVPTTLPPNSRHGKLF 847
               S  T PPS              L+V   ++T S         V T+   +       
Sbjct: 1146 EGTSIPTSPPSEGTTPLASMPVSTTLVVSSEANTLSTTPVDSKTQVATSTEAS------- 1198

Query: 848  SPSKEAELTFRQHLNSISMQSDFFLPKPRKLRNRHLRKPLVV--QRTLLPRPSENQSHNV 905
            SP   AE+T        SM +     +   L +  +R   V   + + L     + S  V
Sbjct: 1199 SPPPTAEVT--------SMPTSTPGERSTPLTSMPVRHTPVASSEASTLSTSPVDTSTPV 1250

Query: 906  CSFSILSNSSVTGRGSFRPIQSSLTKAALSRPI---VPKVLPPQATSHLASAIDL--AAT 960
             + +  S+S  T  G+  P  ++   + L   I      V  P+A++ L + +D      
Sbjct: 1251 TTSAETSSSPTTAEGTSLPTSTTSEGSTLLTSIPVSTTLVTSPEASTLLTTPVDTKGPVV 1310

Query: 961  SAGILSGNPLPALDTEGLS--------GISPLSSDEV--TGAISGQDSTGTHQDGDTLPT 1010
            ++  +S +P PA   EG S        G +PL+S  V  T   S   S  +    D    
Sbjct: 1311 TSNEVSSSPTPA---EGTSMPTSTYSEGRTPLTSIPVNTTLVASSAISILSTTPVDNSTP 1367

Query: 1011 VGGSDPFVSIPSRPEQEPVADSFQGSSVLSLSELPKAPLQNGLSIPLSSSESSSTRLSPP 1070
            V  S    S P+  E   + +S        L+ +P +      + P+ SSE+S+   +P 
Sbjct: 1368 VTTSTEACSSPTTSEGTSMPNSNPSEGTTPLTSIPVS------TTPVVSSEASTLSATP- 1420

Query: 1071 DVSALLDISLPGPPEDALSQGEPATHISDSIIEIAISSGQYG-EGVPLSPAKLNGSDSSK 1129
                 +D S PG    A +   P T    SI     S G+   + +P+S   +  S++S 
Sbjct: 1421 -----VDTSTPG-TTSAEATSSPTTAEGISIPTSTPSEGKTPLKSIPVSNTPVANSEAST 1474

Query: 1130 SLPSPSSSPQPHWIASPTHDPQWYPSDSTDSSLSSLFASFISPEKSRKMLPTPIGTNSGT 1189
               +P  S  P  + S        P++ T  ++S+        E S  +   P+ T +  
Sbjct: 1475 LSTTPVDSNSP-VVTSTAVSSSPTPAEGTSIAIST------PSEGSTALTSIPVSTTTVA 1527

Query: 1190 S 1190
            S
Sbjct: 1528 S 1528



 Score = 48.1 bits (113), Expect = 5e-05
 Identities = 148/740 (20%), Positives = 255/740 (34%), Gaps = 111/740 (15%)

Query: 485  SSGESSPESAPGEGAA----------LSLSSPDAPDRPPPRHQDTG-----PCLEKTPAE 529
            S G S P S P EG+           L +SS D+     P    T           T AE
Sbjct: 3149 SEGTSMPTSTPSEGSTPLTYMPVSTMLVVSSEDSTLSATPVDTSTPVTTSTEATSSTTAE 3208

Query: 530  GRDSPTREP--GALPCAC---GQLPDLEDELSLLDPLPRYLKSCQDLIVPEQCRCADTRP 584
            G   PT  P  G  P         P    E S+L   P          V        +  
Sbjct: 3209 GTSIPTSTPSEGMTPLTSVPVSNTPVASSEASILSTTP----------VDSNTPLTTSTE 3258

Query: 585  GSEQPPLGGAASPEVLAPVSKEAADLAPTGPSPRPGPGLLLDVCTKDLADAPAEELQEKG 644
             S  PP             + E   +  + PS    P   + V T  +A +    L    
Sbjct: 3259 ASSSPP-------------TAEGTSMPTSTPSEGSTPLTSMPVSTTTVASSETSTLSTTP 3305

Query: 645  SPAGPPPSQGQPAARPPKEVPASRLAQQLREEGWNLQT-----------SESLTLAEVYL 693
            +    P +    A+  P     + +      EG    T           SE+ TL+   +
Sbjct: 3306 ADTSTPVTTYSQASSSPPIADGTSMPTSTYSEGSTPLTNMSFSTTPVVSSEASTLSTTPV 3365

Query: 694  MMGKPSKLQLEYDWLGPGRQDPRPGSLPTALHKQRLLSCLLKLISTEVNPKLALEANTIS 753
                P     E   L P   +    S+PT+   +         +ST   P ++ E NT+S
Sbjct: 3366 DTSTPVTTSTEAS-LSPTTAEGT--SIPTSSPSEGTTPLASMPVST--TPVVSSEVNTLS 3420

Query: 754  TASVRPAQEEQSMTPPGKVVTVSSRS--PRCPRNQASLRSSKTFPPSSAPCSSG----LR 807
            T  V       + T      T++  +  P    ++ S   S   P S+ P +S     L 
Sbjct: 3421 TTPVDSNTLVTTSTEASSSPTIAEGTSLPTSTTSEGSTPLS-IMPLSTTPVASSEASTLS 3479

Query: 808  NPPRPLLVPGPSSTGSNDSDGGLFAVPTTLPPNSRHGKLFSPSKEAELTFR-------QH 860
              P     P  +S+ +N S         T  P S  G+  +P     ++           
Sbjct: 3480 TTPVDTSTPVTTSSPTNSSPT---TAEVTSMPTSTAGEGSTPLTNMPVSTTPVASSEAST 3536

Query: 861  LNSISMQSDFFLPKPRKLRNRHLRKPLVVQRTLLPRPSENQSHNVCSFSILSNSSVTGRG 920
            L++  + S+ F+    +  +     P  +Q T +   + ++  +  +  +LS++ VT   
Sbjct: 3537 LSTTPVDSNTFVTSSSQASS----SPATLQVTTMRMSTPSEGSSSLTTMLLSSTYVTSSE 3592

Query: 921  SFRPIQSSLTKA--------ALSRPIVPKV--LPPQATSHLASAIDLAATSAGILSGNPL 970
            +  P   S+ ++        + S P  P+V  LP    S +++ + +   S   ++    
Sbjct: 3593 ASTPSTPSVDRSTPVTTSTQSNSTPTPPEVITLPMSTPSEVSTPLTIMPVSTTSVT---- 3648

Query: 971  PALDTEGLSGISPLSSDEVTGAISGQDSTGTHQDGDTLPTVGGSDPFVSIPSRPEQEPVA 1030
              +   G +   P+ +       +   S+    +G T+P    S+    + + P      
Sbjct: 3649 --ISEAGTASTLPVDTSTPVITSTQVSSSPVTPEGTTMPIWTPSEGSTPLTTMPVSTTRV 3706

Query: 1031 DSFQGSSVLSLSELPKAPLQNGLSIPLSSSESSSTRLSPPDVSALLDISLPGPPEDALSQ 1090
             S +GS++ + S +   P+        SS+   ST +S   VS  ++IS  G     L  
Sbjct: 3707 TSSEGSTLSTPSVVTSTPVTTSTEAISSSATLDSTTMS---VSMPMEISTLG--TTILVS 3761

Query: 1091 GEPATHISDS------IIEIAISSGQYGEGVPLSPAKLNGSDSSKSLPSPSSSPQPHWIA 1144
              P T   +S       +  ++S     EG   SP  L G   + ++P  ++S +   + 
Sbjct: 3762 TTPVTRFPESSTPSIPSVYTSMSMTTASEG-SSSPTTLEG---TTTMPMSTTSERSTLLT 3817

Query: 1145 SPTHDPQWYPSDSTDSSLSS 1164
            +    P    S S  S+LS+
Sbjct: 3818 TVLISPISVMSPSEASTLST 3837



 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 164/771 (21%), Positives = 252/771 (32%), Gaps = 122/771 (15%)

Query: 495  PGEGAALSLSSPDAPDRPPPRHQDTGPCLEKTPAEGRDSPTREP--GALPCAC---GQLP 549
            P   +  S  S    D   P    T      T AEG   PT  P  G  P A       P
Sbjct: 2408 PVVSSEASTHSTTPVDTSTPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTP 2467

Query: 550  DLEDELSLLDPLPRYLKSCQDLIVPEQCRCADTRPGSEQPPLGGAASPEVL--------A 601
             +  E   L   P  + +   +    +   + T       P+  A+    L         
Sbjct: 2468 VVSSEAGTLSTTP--VDTSTPMTTSTEASSSPTTAEDIVVPISTASEGSTLLTSIPVSTT 2525

Query: 602  PVSKEAADLAPTGPSPRPGPGLLLDVCTKDLADAPAEELQEKGSPAGPPPSQGQPAARPP 661
            PV+   A    T P     P +     +     A    +       G  P +  P +  P
Sbjct: 2526 PVASPEASTLSTTPVDSNSPVVTSTEISSSATSAEGTSMPTSTYSEGSTPLRSMPVSTKP 2585

Query: 662  KEVPASRLAQQLREEGWNLQTSESLTLAEVYLMMGKPSKLQLEYDWLGPGRQDPRPGSLP 721
                              L +SE+ TL+   +    P     E        +D    S+P
Sbjct: 2586 ------------------LASSEASTLSTTPVDTSIPVTTSTETSSSPTTAKDT---SMP 2624

Query: 722  TALHKQRLLSCLLKLISTEVNPKLALEANTISTASV--------------RPAQEEQSMT 767
             +   +   S    L+ST   P  + EA+T+ST  V               P   E S  
Sbjct: 2625 ISTPSEVSTSLTSILVSTM--PVASSEASTLSTTPVDTRTLVTTSTGTSSSPTTAEGSSM 2682

Query: 768  P---PGKVVTVSSR---SPRCPRNQASLRSSKTFPPSSAPCSSGLRNPPRPLLVPGPSST 821
            P   PG+  T  +    S     N  +   S T   +S P ++       P    G S  
Sbjct: 2683 PTSTPGERSTPLTNILVSTTLLANSEASTLSTTPVDTSTPVTTSAEASSSPTTAEGTSMR 2742

Query: 822  GSNDSDGGL---FAVPTTLPPNSRHGKLFSPSKEAELTFRQHLNSISMQSDFFLPKPRKL 878
             S  SDG       + +TLP  S      S +  A  T      S    S    P   ++
Sbjct: 2743 ISTPSDGSTPLTSILVSTLPVASSEASTVSTT--AVDTSIPVTTSTEASSS---PTTAEV 2797

Query: 879  RNRHLRKPLVVQRTLLPRPSENQSHNVCSFSILSNSSVTGRGSFRPIQSSLTKAALSRPI 938
             +     P     T  P  S   +H   + S     S T   +  P+ +S TKA+ S   
Sbjct: 2798 TSMPTSTP---SETSTPLTSMPVNHTPVASSEAGTLSTTPVDTSTPVTTS-TKASSSPTT 2853

Query: 939  VPKVLPPQATSHLASAI---------DLAATSAGILSGNPLPA-----LDTEGLSGISPL 984
               ++ P +T+   S +          +A++ A  LS  P+         TEG S  SP 
Sbjct: 2854 AEGIVVPISTASEGSTLLTSIPVSTTPVASSEASTLSTTPVDTSIPVTTSTEGSS--SPT 2911

Query: 985  SSDEVTGAISGQDSTGTHQDG---DTLPTVGGSDPFVSIPSRPEQEPVADSFQGSSVLSL 1041
            +++  +  IS      T        T+P  G     +S      + PV  S + SS  + 
Sbjct: 2912 TAEGTSMPISTPSEVSTPLTSILVSTVPVAGSEASTLSTTPVDTRTPVTTSAEASSSPTT 2971

Query: 1042 SELPKAPLQNG------------LSIPLSSSESSSTRLSPPDVSALLDISL--------- 1080
            +E    P+                ++P++SSE+S+   +P D S  +  S          
Sbjct: 2972 AEGTSMPISTPGERRTPLTSMSVSTMPVASSEASTLSRTPADTSTPVTTSTEASSSPTTA 3031

Query: 1081 --PGPPEDALSQGE-PATHISDSIIEIAISSGQYGEGVPLSPAKLNGSDSSKSLPSPSSS 1137
               G P    S+G  P T I  S   +AI      E   LS   ++ +    +    SSS
Sbjct: 3032 EGTGIPISTPSEGSTPLTSIPVSTTPVAIP-----EASTLSTTPVDSNSPVVTSTEVSSS 3086

Query: 1138 PQPHWIASPTHDP-QWYPSDSTDSSLSSLFASFISPEKSRKMLPTPIGTNS 1187
            P P   A  T  P   Y   ST  +   +  + ++      +  TP+ T++
Sbjct: 3087 PTP---AEGTSMPISTYSEGSTPLTGVPVSTTPVTSSAISTLSTTPVDTST 3134



 Score = 40.0 bits (92), Expect = 0.014
 Identities = 140/712 (19%), Positives = 231/712 (32%), Gaps = 113/712 (15%)

Query: 493  SAPGEGAALSLSSPDAPDRPPPRHQDTGPCLEKTPAEGRDSPTREP--GALPCACGQLPD 550
            + P   +A+S  S    D   P    T      T +EG   PT  P  G+ P        
Sbjct: 3114 TTPVTSSAISTLSTTPVDTSTPVTTSTEAHSSPTTSEGTSMPTSTPSEGSTPLT------ 3167

Query: 551  LEDELSLLDPLPRYLKSCQDLIVPEQCRCADTRPGSEQPPLGGAASPEVLAPVSKEAADL 610
                         Y+     L+V  +       P     P+    S E  +  + E   +
Sbjct: 3168 -------------YMPVSTMLVVSSEDSTLSATPVDTSTPV--TTSTEATSSTTAEGTSI 3212

Query: 611  APTGPSPRPGPGLLLDVCTKDLADAPAEELQEKGSPAGPPPSQGQPAARPPKEVPASRLA 670
              + PS    P   + V    +A + A  L      +  P +    A+  P     + + 
Sbjct: 3213 PTSTPSEGMTPLTSVPVSNTPVASSEASILSTTPVDSNTPLTTSTEASSSPPTAEGTSMP 3272

Query: 671  QQLREEGWNLQTS-----ESLTLAEVYLMMGKPSKLQLEYDWLGPGRQDPRPG---SLPT 722
                 EG    TS      ++  +E   +   P+               P      S+PT
Sbjct: 3273 TSTPSEGSTPLTSMPVSTTTVASSETSTLSTTPADTSTPVTTYSQASSSPPIADGTSMPT 3332

Query: 723  ALHKQRLLSCLLKLISTEVNPKLALEANTISTASVRPAQEEQSMTPPGKVVTVSSRSPRC 782
            + + +   S  L  +S    P ++ EA+T+ST  V       + TP    VT S+ +   
Sbjct: 3333 STYSEG--STPLTNMSFSTTPVVSSEASTLSTTPV------DTSTP----VTTSTEASLS 3380

Query: 783  PRNQASLRSSKTFPPSSAPCSSGLRNPPRPLLVPGPSSTGSNDSDGGLFAVPTTLPPNSR 842
            P       +  T  P+S+P          PL     S+T    S+       +T P +S 
Sbjct: 3381 PTT-----AEGTSIPTSSPSEG-----TTPLASMPVSTTPVVSSEVNTL---STTPVDS- 3426

Query: 843  HGKLFSPSKEAELTFRQHLNSISMQSDFFLPKPRKLRNRHLRKPLVVQRTLLPRPSENQS 902
               L + S EA                                P + + T LP  + ++ 
Sbjct: 3427 -NTLVTTSTEAS-----------------------------SSPTIAEGTSLPTSTTSEG 3456

Query: 903  HNVCSFSILSNSSVTGRGSFRPIQSSLTKAALSRPIVPKVLPPQATSHLASAIDLAATSA 962
                S   LS + V    S      S T    S P+      P  +S   + +    TS 
Sbjct: 3457 STPLSIMPLSTTPV---ASSEASTLSTTPVDTSTPVTTS--SPTNSSPTTAEVTSMPTST 3511

Query: 963  GILSGNPLPALDTEGLSGISPLSSDE-----VTGAISGQDSTGTHQDGDTLPTVGGSDPF 1017
                  PL  +        +P++S E      T   S    T + Q   +  T+  +   
Sbjct: 3512 AGEGSTPLTNMPV----STTPVASSEASTLSTTPVDSNTFVTSSSQASSSPATLQVTTMR 3567

Query: 1018 VSIPSRPEQEPVADSFQGSSVLSLSELPKAPLQNGLSIPLSSSESSSTRLSPPDVSALLD 1077
            +S PS             + V S      +      S P+++S  S++  +PP+V     
Sbjct: 3568 MSTPSEGSSSLTTMLLSSTYVTSSEASTPSTPSVDRSTPVTTSTQSNSTPTPPEV----- 3622

Query: 1078 ISLPGPPEDALSQGEPATHISDSIIEIAISSGQYGEGVPL--SPAKLNGSDSSKSLPSPS 1135
            I+LP      +S   P T +  S   + IS       +P+  S   +  +  S S  +P 
Sbjct: 3623 ITLPMSTPSEVS--TPLTIMPVSTTSVTISEAGTASTLPVDTSTPVITSTQVSSSPVTPE 3680

Query: 1136 SSPQPHWIASPTHDPQWYPSDSTDSSLSSLFASFISPEKSRKMLPTPIGTNS 1187
             +  P W  S    P      ST    SS  ++  +P     +  TP+ T++
Sbjct: 3681 GTTMPIWTPSEGSTPLTTMPVSTTRVTSSEGSTLSTPS---VVTSTPVTTST 3729



 Score = 37.7 bits (86), Expect = 0.070
 Identities = 153/790 (19%), Positives = 261/790 (33%), Gaps = 112/790 (14%)

Query: 479  AADALQSSGESSPESAPGEGAAL---------SLSSPDAPDRPPPRHQDTGPCLEKTPAE 529
            A+ +  + G S   SAP EG+ L          ++SP+A            P +  T   
Sbjct: 2081 ASSSATAEGSSMTISAPSEGSPLLTSIPLSTTPVASPEASTLSTTPVDSNSPVITSTEVS 2140

Query: 530  GRDSPTREPGALPCACGQLPDLEDELSLLDPLPRYLKSCQDLIVPEQCRCADTRPGSEQP 589
                PT           Q     D  + L  +P        ++         T P     
Sbjct: 2141 SSPIPTEGTSM------QTSTYSDRRTPLTSMP----VSTTVVASSAISTLSTTPVDTST 2190

Query: 590  PLGGAASPEVLAPVSKEAADLAPTGPSPRPGPGLLLDVCTKDLADAPAEELQEKGSPAGP 649
            P+  +      +P + E   +  + PS    P   + V T  +  + A  L         
Sbjct: 2191 PVTNSTEAR-SSPTTSEGTSMPTSTPSEGSTPFTSMPVSTMPVVTSEASTLSATPVDTST 2249

Query: 650  PPSQGQPAARPPKEVPASRLAQQLREEGWNLQTS--ESLTL---AEVYLMMGKPSKLQLE 704
            P +    A   P     + +      EG    TS   S TL   +EV  +   P      
Sbjct: 2250 PVTTSTEATSSPTTAEGTSIPTSTLSEGTTPLTSIPVSHTLVANSEVSTLSTTPVDSNTP 2309

Query: 705  YDWLGPGRQDPRPG---SLPTALHKQRLLSCLLKLISTEVNPKLALEANTIST------- 754
            +         P      S+PT+   +         +ST +    + E +T+ST       
Sbjct: 2310 FTTSTEASSPPPTAEGTSMPTSTSSEGNTPLTRMPVSTTM--VASFETSTLSTTPADTST 2367

Query: 755  -------ASVRPAQEEQSMTPPGKVVTVSSRSPRCPRNQASLRSSK------TFPPSSAP 801
                   A   P   + +  P       S+     P +   + SS+      T   +S P
Sbjct: 2368 PVTTYSQAGSSPTTADDTSMPTSTYSEGSTPLTSVPVSTMPVVSSEASTHSTTPVDTSTP 2427

Query: 802  CSSGLRNPPRPLLVPGPSSTGSNDSDG--GLFAVPTTLPP--NSRHGKLFSPSKEAE--- 854
             ++       P    G S   S  S+G   L ++P +  P  +S  G L +   +     
Sbjct: 2428 VTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTPVVSSEAGTLSTTPVDTSTPM 2487

Query: 855  LTFRQHLNSISMQSDFFLPKPRKLRNRHLRKPLVVQRTLLPRPSE--------NQSHNVC 906
             T  +  +S +   D  +P         L   + V  T +  P          + +  V 
Sbjct: 2488 TTSTEASSSPTTAEDIVVPISTASEGSTLLTSIPVSTTPVASPEASTLSTTPVDSNSPVV 2547

Query: 907  SFSILSNSSVTGRGSFRPIQ--SSLTKAALSRPIVPKVLPPQATSHLASA---IDLAATS 961
            + + +S+S+ +  G+  P    S  +    S P+  K L     S L++      +  T+
Sbjct: 2548 TSTEISSSATSAEGTSMPTSTYSEGSTPLRSMPVSTKPLASSEASTLSTTPVDTSIPVTT 2607

Query: 962  AGILSGNPLPALDTEGLSGISPLSSDEVTGAI-------SGQDSTGTHQDGDTLPTVGGS 1014
            +   S +P  A DT          S  +T  +       S + ST +    DT   V  S
Sbjct: 2608 STETSSSPTTAKDTSMPISTPSEVSTSLTSILVSTMPVASSEASTLSTTPVDTRTLVTTS 2667

Query: 1015 DPFVSIPSRPEQEPVADSFQGSSVLSLSELPKAPLQNGL--SIPLSSSESSSTRLSPPDV 1072
                S P+  E   +  S  G            PL N L  +  L++SE+S+   +P D 
Sbjct: 2668 TGTSSSPTTAEGSSMPTSTPGER--------STPLTNILVSTTLLANSEASTLSTTPVDT 2719

Query: 1073 SALLDISLPGPPEDALSQG------------EPATHISDSIIEIAISSGQYGEGVPLSPA 1120
            S  +  S         ++G             P T I  S + +A S     E   +S  
Sbjct: 2720 STPVTTSAEASSSPTTAEGTSMRISTPSDGSTPLTSILVSTLPVASS-----EASTVSTT 2774

Query: 1121 KLNGSDSSKSLPSPSSSPQPHWIAS-PTHDPQWYPSDSTDSSLSSLFASF--ISPEKSRK 1177
             ++ S    +    SSSP    + S PT  P       T + L+S+  +   ++  ++  
Sbjct: 2775 AVDTSIPVTTSTEASSSPTTAEVTSMPTSTP-----SETSTPLTSMPVNHTPVASSEAGT 2829

Query: 1178 MLPTPIGTNS 1187
            +  TP+ T++
Sbjct: 2830 LSTTPVDTST 2839



 Score = 37.4 bits (85), Expect = 0.092
 Identities = 112/494 (22%), Positives = 188/494 (38%), Gaps = 91/494 (18%)

Query: 719  SLPTALHKQRLLSCLLKLISTEVNPKLALEANTISTASVRPAQEEQSMTPPGKVVTVSSR 778
            S+PT+   +   S  L  +S    P  + EA+T+ST  V       + TP    VT SS 
Sbjct: 500  SMPTSTPSEG--STPLTSMSVSTMPVASSEASTLSTTPV------DTSTP----VTTSSE 547

Query: 779  SPRCPRNQASLRSSKTFPPSSAPC--SSGLRNPP---RPLLVPGPSSTGSNDSDGGLFAV 833
            +     + +S     T  P+S P   S+ L N P   R ++    S+T +  +D   F  
Sbjct: 548  A-----SSSSTTPEGTSIPTSTPSEGSTPLTNMPVSTRLVVSSEASTTSTTPADSNTFVT 602

Query: 834  PTTLPPNSRHGKLFSPSKEAELTFRQHLNSISMQSDFFLPKPRKLRNRHLRKPLVVQR-- 891
             ++        +  S S  AE T        SM +  +  +   + +  +   LV     
Sbjct: 603  TSS--------EASSSSTTAEGT--------SMPTSTYSERGTTITSMSVSTTLVASSEA 646

Query: 892  -TLLPRPSENQSHNVCSFSILSNSSVTGRGSFRPIQSSLTKAALSRPIVPKVLPPQATSH 950
             TL   P ++ +  V + +  ++SS T  G+  P  S+ T+   S P+         TS 
Sbjct: 647  STLSTTPVDSNTP-VTTSTEATSSSTTAEGTSMPT-STYTEG--STPL---------TSM 693

Query: 951  LASAIDLAATSAGILSGNPLPALDTEGLSGISPLSSDEVTGAISGQDSTGTHQDGDTLPT 1010
              +   +A++ A  LS  P+              +S  VT +     S  T  DG ++PT
Sbjct: 694  PVNTTLVASSEASTLSTTPVD-------------TSTPVTTSTEASSSPTT-ADGASMPT 739

Query: 1011 VGGSDPFVSIPSRPEQEPVADSFQGSSVLSLSELPKAPLQNGLSIPLSSSESSSTRLSPP 1070
               S+    + S P  + +  S + S+      L   PL     I  S+  S S   +  
Sbjct: 740  STPSEGSTPLTSMPVSKTLLTSSEAST------LSTTPLDTSTHITTSTEASCSPTTTE- 792

Query: 1071 DVSALLDISLPGPPEDALSQGEPATHISDSIIEIAISSGQYGEGVPLSPAKLNGSDSSKS 1130
                 + IS P       S+G P      + I ++I+     E   LS   ++ +    +
Sbjct: 793  --GTSMPISTP-------SEGSPLL----TSIPVSITPVTSPEASTLSTTPVDSNSPVTT 839

Query: 1131 LPSPSSSPQP---HWIASPTHDPQWYPSDSTDSSLSSLFASFISPEKSRKMLPTPIGTNS 1187
                SSSP P     + + T+     P  S   S + +  S IS   +  +  +   TNS
Sbjct: 840  STEVSSSPTPAEGTSMPTSTYSEGRTPLTSMPVSTTLVATSAISTLSTTPVDTSTPVTNS 899

Query: 1188 GTSLLGPSLLDGNS 1201
              +   P+  +G S
Sbjct: 900  TEARSSPTTSEGTS 913



 Score = 37.0 bits (84), Expect = 0.12
 Identities = 165/820 (20%), Positives = 267/820 (32%), Gaps = 132/820 (16%)

Query: 485  SSGESSPESAPGEGAALSLSSPDAPDRPPPRHQDTGPCLEKTPAEGRDSPTREPGALPCA 544
            S G S P S P EG     S P +     P        L  TP +     T  PG     
Sbjct: 1381 SEGTSMPNSNPSEGTTPLTSIPVSTT---PVVSSEASTLSATPVD-----TSTPGTTSAE 1432

Query: 545  CGQLPDLEDELSLLDPLPRYLKSCQDLIVPEQCRCADTRPGSEQPPLGGAASPEVLA--- 601
                P   + +S+    P   K+    I       A++   +       + SP V +   
Sbjct: 1433 ATSSPTTAEGISIPTSTPSEGKTPLKSIPVSNTPVANSEASTLSTTPVDSNSPVVTSTAV 1492

Query: 602  ---PVSKEAADLAPTGPSPRPGPGLLLDVCTKDLADAPAEELQEKGSPAGPPPSQGQPAA 658
               P   E   +A + PS        + V T  +A +    L    +    P +    A+
Sbjct: 1493 SSSPTPAEGTSIAISTPSEGSTALTSIPVSTTTVASSEINSLSTTPAVTSTPVTTYSQAS 1552

Query: 659  RPPKEVPASRLAQQLREEGWNLQTSESLTL-----AEVYLMMGKP--SKLQLEYDWLGPG 711
              P     + +      EG    TS  ++      +E   +   P  SK Q+        
Sbjct: 1553 SSPTTADGTSMQTSTYSEGSTPLTSLPVSTMLVVSSEANTLSTTPIDSKTQVTASTEASS 1612

Query: 712  RQDPRPGSLPTALHKQRLLSCLLKLISTEVNPKLALEANTISTASV-------------- 757
                   S+  +   +   S LL  I     P  + EA+T+ST  V              
Sbjct: 1613 STTAEGSSMTISTPSEG--SPLLTSIPVSTTPVASPEASTLSTTPVDSNSPVITSTEVSS 1670

Query: 758  RPAQEEQSMTPP-----GKVVTVSSRSPRCPRNQASLRSSKTFP-PSSAPCSSGLRNPPR 811
             P   E +  P      G+    S      P   +++ +  T P  +S P ++       
Sbjct: 1671 SPTPAEGTSMPTSTYTEGRTPLTSITVRTTPVASSAISTLSTTPVDNSTPVTTSTEARSS 1730

Query: 812  PLLVPGPSSTGSNDSDGGLFAVPTTLPPNSRHGKLFSPSKEAELTFRQHLNSISMQSDFF 871
            P    G S   S  S+G     P T  P S    L S +     T       ++  ++  
Sbjct: 1731 PTTSEGTSMPNSTPSEG---TTPLTSIPVSTTPVLSSEASTLSATPIDTSTPVTTSTEA- 1786

Query: 872  LPKPRKLRNRHLRKPLVVQRTLLPRPSENQSHNVCSFSILSNSSVTGRGSFRPIQSSL-- 929
               P       +     +   + P  S   SH + + S  S  S T   S  P+ +S   
Sbjct: 1787 TSSPTTAEGTSIPTS-TLSEGMTPLTSTPVSHTLVANSEASTLSTTPVDSNSPVVTSTAV 1845

Query: 930  ---------TKAALSRPIVPKV----LPPQATSHLASAIDLAATSAGILS---------- 966
                     T  A S P         +P   T+  +S  +  +T+  + S          
Sbjct: 1846 SSSPTPAEGTSIATSTPSEGSTALTSIPVSTTTVASSETNTLSTTPAVTSTPVTTYAQVS 1905

Query: 967  -------GNPLP-ALDTEGLSGIS--PLSSDEVTGA------------------ISGQDS 998
                   G+ +P +   EG   ++  P+S+  V  +                   S   S
Sbjct: 1906 SSPTTADGSSMPTSTPREGRPPLTSIPVSTTTVASSEINTLSTTLADTRTPVTTYSQASS 1965

Query: 999  TGTHQDGDTLPTVG---GSDPFVSIP-----------SRPEQEPVADSFQGSSVLSLSEL 1044
            + T  DG ++PT     GS P  S+P           S     PV  S   ++    S  
Sbjct: 1966 SPTTADGTSMPTPAYSEGSTPLTSMPLSTTLVVSSEASTLSTTPVDTSTPATTSTEGSSS 2025

Query: 1045 PKAPLQNGLSIPLSSSESSSTRLSPPDVSALLDISLPG-----PPEDALSQGEPATHISD 1099
            P      G SI  S+    +T L+   VS  L +S  G      P D+ +Q   +T  S 
Sbjct: 2026 PTT--AGGTSIQTSTPSERTTPLAGMPVSTTLVVSSEGNTLSTTPVDSKTQVTNSTEASS 2083

Query: 1100 SII----EIAISSGQYGE----GVPLSPAKLNGSDSSKSLPSPSSSPQPHWIASPTHDPQ 1151
            S       + IS+   G      +PLS   +   ++S    +P  S  P  I S      
Sbjct: 2084 SATAEGSSMTISAPSEGSPLLTSIPLSTTPVASPEASTLSTTPVDSNSP-VITSTEVSSS 2142

Query: 1152 WYPSDSTDSSLSSLFASFISPEKSRKMLPTPIGTNSGTSL 1191
              P++ T S  +S ++   +P  S  +  T + +++ ++L
Sbjct: 2143 PIPTEGT-SMQTSTYSDRRTPLTSMPVSTTVVASSAISTL 2181



 Score = 32.3 bits (72), Expect = 3.0
 Identities = 54/251 (21%), Positives = 98/251 (39%), Gaps = 40/251 (15%)

Query: 960  TSAGILSGNPLPALDT--------EGLSGIS--PLSSDEVTGAISGQDSTGTHQDGDTLP 1009
            T+A   S +P  A DT        EG + ++  P+S+  V  + +   ST T  D  T  
Sbjct: 425  TTASEASSSPTTAEDTSIATSTPSEGSTPLTSMPVSTTPVASSEASNLST-TPVDSKTQV 483

Query: 1010 TVG----GSDPFVSIPSRPEQEPVADSFQGSSVLSLSELPKAPLQNGLSIPLSSSESSST 1065
            T       S P   + S P   P     +GS+ L+   +         ++P++SSE+S+ 
Sbjct: 484  TTSTEASSSPPTAEVNSMPTSTPS----EGSTPLTSMSVS--------TMPVASSEASTL 531

Query: 1066 RLSPPDVSALLDISLPGPPEDALSQG---------EPATHISDSIIEIAISSGQYGEGVP 1116
              +P D S  +  S          +G         E +T +++  +   +          
Sbjct: 532  STTPVDTSTPVTTSSEASSSSTTPEGTSIPTSTPSEGSTPLTNMPVSTRLVVSSEASTTS 591

Query: 1117 LSPAKLNGSDSSKSLPSPSSSPQPHWIASPTHDPQWYPSDSTDSSLSSLFASFISPEKSR 1176
             +PA  N   ++ S  S SSS      + PT     Y    T  +  S+  + ++  ++ 
Sbjct: 592  TTPADSNTFVTTSSEAS-SSSTTAEGTSMPT---STYSERGTTITSMSVSTTLVASSEAS 647

Query: 1177 KMLPTPIGTNS 1187
             +  TP+ +N+
Sbjct: 648  TLSTTPVDSNT 658


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 105/424 (24%), Positives = 146/424 (34%), Gaps = 56/424 (13%)

Query: 467 GAEGKGVGRPPPAADALQSSGESSPESAPGEGAALSLSSPDAPDR----PPPRHQDTGPC 522
           GA G  VGR P A  A    G + PESAP  G   + S P A  R    PP ++   GP 
Sbjct: 48  GAAG-AVGRKPLAERAGGIGGATIPESAPRAGPTRT-SRPPASGRGERAPPAKNTSPGP- 104

Query: 523 LEKTPAEGRDSPTREPGAL-----------PCACGQLPDLEDELSLLDPLPRYLKS---- 567
                + GR S T  PG L             A G+  +     +L     R        
Sbjct: 105 ---VSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPG 161

Query: 568 CQDLIVPEQCRCADTRPGSEQPPLGGAASPEVLAPVSK--EAADLAPTGPSP----RPGP 621
                +  + R A T  G  +P       P    P      A++ + T PSP    RP  
Sbjct: 162 TPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSA 221

Query: 622 GLLLDVCTKDLADAPAEELQE--------KGSPAGPP-PSQGQP----AARPPKEVPASR 668
           G  L         + A  L          +G+P  P  PSQ +P    A RPP+  P  +
Sbjct: 222 GGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRK 281

Query: 669 LAQQLREEGWNLQTSESLTLA-EVYLMMGKPSKLQLEYDWLGPGRQDPRPGSLPTALHKQ 727
            A         L +S   T +         P  LQ       P      P    T+L   
Sbjct: 282 DAAPALGP---LSSSPLATPSPSAPPSPSAPPSLQTL-----PSPPATPPSQATTSLGSP 333

Query: 728 RLLSCLLKLISTEVNPKLALEANTISTASVRPAQEEQSMTPPGKVVTVSSRSPRCPRNQA 787
            L +    L S  ++P            ++ P Q   S      +  +++ SP+ P   A
Sbjct: 334 TLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALA 393

Query: 788 -SLRSSKTFPPSSAPCSSGLRNPPRPLLVPGPSSTGSNDSDGGLFAVPTTLPPNSRHGKL 846
             L  +   PP S P  +    P  P +   PS+T  + +   L A P  +PP+      
Sbjct: 394 VHLLQAPFSPPPSPPVQAPFSPPASPPV--SPSATPPSQAPPSLAAPPLQVPPSPPASPP 451

Query: 847 FSPS 850
            SPS
Sbjct: 452 MSPS 455



 Score = 47.8 bits (112), Expect = 7e-05
 Identities = 108/434 (24%), Positives = 146/434 (33%), Gaps = 92/434 (21%)

Query: 456 TARGQVKCPRSGAEGKGVG----RPP----PAADALQSSG--ESSPESAPGEGAALSLSS 505
           +ARG  + P   ++ K  G    RPP    P  DA  + G   SSP + P      S S+
Sbjct: 249 SARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATP------SPSA 302

Query: 506 PDAPDRPPPRHQDTGPCLEKTPAEGRDSPTREPGALPCACGQLPDLEDELSLLDPLPRYL 565
           P +P  P        P L+  P+     P   P     + G  P L+   S L   P   
Sbjct: 303 PPSPSAP--------PSLQTLPS----PPATPPSQATTSLGS-PTLQATHSFLPSPP--- 346

Query: 566 KSCQDLIVPEQCRCADTRPGSEQPPLGGAASPEVLAPVSKEAADLAPTGPSPRPGPGLLL 625
                 + P         P    PPL    SP    P+S  A       PSP+    L +
Sbjct: 347 ------LSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLAT------PSPQAPNALAV 394

Query: 626 DVCTKDLADAPAEELQ--------EKGSPAGPPPSQGQPA-ARPPKEVPASRLAQQLREE 676
            +     +  P+  +Q           SP+  PPSQ  P+ A PP +VP S  A      
Sbjct: 395 HLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSP 454

Query: 677 GWNLQTSESLTLAEVYLMMGKPSKLQLEYDWLGPGRQDPRPGSLPTALHKQRLLSCLLKL 736
                      LA   L + KP           P +  P P   P +   Q   S     
Sbjct: 455 SATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSP---PASFPGQAPFS----- 506

Query: 737 ISTEVNPKLALEANTISTASVRPAQEEQSMTPPGKVVTVSSRSPRCPRNQASLRSSKTFP 796
                 P  +L  + ++T    P Q    +  P  ++ V    P  P  QA  R     P
Sbjct: 507 ------PSASLPMSPLATP---PPQAPPVLAAP--LLQVPPSPPASPTLQAPRR-----P 550

Query: 797 PSSAPCSS--------GLRNPPRPLLVPGPSSTGSNDSDGGLFAVPTTLPPNSR------ 842
           P+  P +S         L   P P     PSST S     G  +  T+ P   R      
Sbjct: 551 PTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGP 610

Query: 843 -HGKLFSPSKEAEL 855
             G   SP  +AEL
Sbjct: 611 EGGAAASPPPDAEL 624



 Score = 36.2 bits (82), Expect = 0.20
 Identities = 53/201 (26%), Positives = 69/201 (34%), Gaps = 31/201 (15%)

Query: 476 PPPAADALQSSGESSPESAPGEGAALSLSSPDAPDRPPPRHQDTGPCLEKTPAEGRDSPT 535
           P P A    S   + P  AP   AA  L     P + PP      P L+  P+     P 
Sbjct: 444 PSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPAL--ATPPLQALPSPPASFPG 501

Query: 536 REP----GALPCACGQLPDLEDELSLLDPLPRYLKSCQDLIVPEQCRCADTRPGSEQPPL 591
           + P     +LP +    P  +    L  PL         L VP     + T     +PP 
Sbjct: 502 QAPFSPSASLPMSPLATPPPQAPPVLAAPL---------LQVPPSPPASPTLQAPRRPPT 552

Query: 592 GGAASPEVLAPVSKEAADLAPTGPSPRPGPGLLLDVCTKDL------ADAPAEELQ---- 641
            G   P+      +    LAP GP P P       +   DL      A +  EEL+    
Sbjct: 553 PG---PDTSVSGPRLTLALAP-GPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDS 608

Query: 642 --EKGSPAGPPPSQGQPAARP 660
             E G+ A PPP     A  P
Sbjct: 609 GPEGGAAASPPPDAELAACHP 629



 Score = 33.5 bits (75), Expect = 1.3
 Identities = 40/168 (23%), Positives = 61/168 (36%), Gaps = 27/168 (16%)

Query: 8   GGSGEDGLKKLGKRAADEESLEGEGAGGADAAEESSGTKRDEKTPRAGADGPP------- 60
           G  G+ GL+     +A+E    G+       +  S+G +RD   P  G   P        
Sbjct: 118 GPLGQKGLRI----SAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRA 173

Query: 61  ------APPGAPQA-PSPPQGSPQDQHHFLRSSVRPQSKRPRKDPPSAVGSGNAGGSGPR 113
                  P  AP A P PP   P       R SV   S+    +P  A     + G G +
Sbjct: 174 AGTEVGLPRPAPSARPRPPTEGP-------RKSVSSASEHSTTEPSPAARRRPSAGGGLQ 226

Query: 114 GKGAEGGGSSSGNVSGVAPAAPAGGSRSSSRNLGSSGGEKEEGKKVRR 161
              +    SS+  +S  A + P+  +R + R        K +G +  R
Sbjct: 227 RPASRSLSSSATPLSSPARSGPS--ARGTPRAPAHPSQPKPKGLQALR 272



 Score = 32.7 bits (73), Expect = 2.3
 Identities = 30/106 (28%), Positives = 43/106 (40%), Gaps = 29/106 (27%)

Query: 50  KTPRAGADG--PPAPPGAPQAPSPPQGSPQDQHHFLRSSVRPQSKRPRKDPPSAVGSGNA 107
           +TP A A G   P PPG+P+ P P               V P + R        +G+  A
Sbjct: 15  RTPAARAPGLLTPRPPGSPRPPPP---------------VTPAALR-------VLGAAGA 52

Query: 108 GGSGPRGKGAEGGGSSSGNVSGVAPAAPAGGSRSSSRNLGSSGGEK 153
            G  P  + A G G ++     +  +AP  G   +SR   S  GE+
Sbjct: 53  VGRKPLAERAGGIGGAT-----IPESAPRAGPTRTSRPPASGRGER 93



 Score = 31.6 bits (70), Expect = 5.0
 Identities = 36/129 (27%), Positives = 48/129 (37%), Gaps = 18/129 (13%)

Query: 8   GGSGEDGLKKLGKRAADEESLEGEGAGGADAAEESSGTKRDEKTPRAGADGPPAPPGAPQ 67
           G    DGL  + +    E +     A GA     S GT   +    AGA      P   +
Sbjct: 657 GPGSADGLCTIYETEGPESATP---APGALDPGPSPGTSGGKAAAGAGAGASSRSPKQAR 713

Query: 68  APSPPQGSPQD---QHHFLRSSVRPQSKRPRKDPPSAVGSGNAGGSGPRGKGAEGGGSSS 124
               P G+ Q    QH   R+ +             A   G AGGSG    GAEGGG + 
Sbjct: 714 LGELPLGALQASVVQHLLSRTLLL------------AAAEGAAGGSGGGPGGAEGGGVTG 761

Query: 125 GNVSGVAPA 133
           G  + ++ A
Sbjct: 762 GARAALSDA 770


>gi|110832843 TBP-associated factor 4 [Homo sapiens]
          Length = 1085

 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 33/94 (35%), Positives = 41/94 (43%), Gaps = 12/94 (12%)

Query: 52  PRAGADGPPAPPGAPQAPSPPQGSPQDQHHFLRSSVRPQSKRPRKDPPSAVGSGNAGGSG 111
           P A A  PP PP AP   + P G P            P +  P   PP+A  +G + G+ 
Sbjct: 263 PAAPAAAPPPPPPAPATLARPPGHPAG----------PPTAAPAVPPPAAAQNGGSAGAA 312

Query: 112 PRGKGAEGG--GSSSGNVSGVAPAAPAGGSRSSS 143
           P    A GG  G S     G A AAPA G ++ S
Sbjct: 313 PAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAES 346



 Score = 43.9 bits (102), Expect = 0.001
 Identities = 55/218 (25%), Positives = 78/218 (35%), Gaps = 38/218 (17%)

Query: 450 IQSGQGTARGQVKCPRSGAEGKGVGRPPPAADALQSSGESSPESAPGEGAALSLSSPDAP 509
           + +G      +++ P  G+ G     P PAA A+ +  E +P          +L++   P
Sbjct: 115 VPAGPAPPAAKLRPPPEGSAGSCA--PVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGP 172

Query: 510 DRPPPRHQDTGPCLEKTPAEGRDSPTREPGAL----PCACGQLPDLEDELSLLDPLPRYL 565
              P      GP   K    G         AL      A   +  + +  + L PLP+  
Sbjct: 173 GPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPK-- 230

Query: 566 KSCQDLIVPEQCRCADTRPGS--EQPPLGGAASPEVLAPVSKEAADLAPTGPSPRPGPGL 623
                             PG+  + PP  GAA+P   A  S  AA  AP  P+  P P  
Sbjct: 231 ---------------PAAPGTVIQTPPFVGAAAPPAPAAPSPPAAP-APAAPAAAPPPP- 273

Query: 624 LLDVCTKDLADAPAEELQEKGSPAGPPPSQGQPAARPP 661
                      APA   +  G PAGPP +   PA  PP
Sbjct: 274 ---------PPAPATLARPPGHPAGPPTA--APAVPPP 300



 Score = 37.0 bits (84), Expect = 0.12
 Identities = 53/198 (26%), Positives = 63/198 (31%), Gaps = 54/198 (27%)

Query: 460 QVKCPRSGAEGKGVGRPPPAADALQSSGESSPESAPGEGAALSLSSPDAPDRPPP----R 515
           +V+   +GA G  V    PA  A       +  +AP EGA      P A   PPP    R
Sbjct: 49  EVRAAAAGALGNHVVSGSPAGAA------GAGPAAPAEGA------PGAAPEPPPAGRAR 96

Query: 516 HQDTGPCLEKTPAEGRDSPTREPGALPCACGQLPDLEDELSLLDPLPRYLKSCQDLIVPE 575
               GP     P+  R  P    G  P A    P  E       P+P             
Sbjct: 97  PGGGGPQRPGPPSPRR--PLVPAGPAPPAAKLRPPPEGSAGSCAPVPA------------ 142

Query: 576 QCRCADTRPGSEQPPLGGAASPEVLAPVSKEAADLAPTGPSPRPGPGLLLDVCTKDLADA 635
               A    G E  P  G A P   A ++  A      GP P PGPG             
Sbjct: 143 ---AAAVAAGPEPAP-AGPAKPAGPAALAARAGPGPGPGPGPGPGPG------------- 185

Query: 636 PAEELQEKGSPAGPPPSQ 653
                   G PAGP  +Q
Sbjct: 186 -------PGKPAGPGAAQ 196



 Score = 35.0 bits (79), Expect = 0.46
 Identities = 51/226 (22%), Positives = 75/226 (33%), Gaps = 17/226 (7%)

Query: 449 GIQSGQGTARGQVKCPRSGAEGKGVGRPPPAADALQSSGESSPESAPGEGAALSLSSPDA 508
           G  +G  TA   V  P +   G   G  P  A A  + G +     PG GAA +  +P  
Sbjct: 285 GHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPA--AGGPAGVSGQPGPGAAAAAPAPGV 342

Query: 509 PDRPPPR-HQDTGPCLEKTPAEGRDSPTREPGALPCACGQLPDLEDELSLLDPLPRYLKS 567
               P R  Q   P  +   A G  S        P   G LP      ++  P P     
Sbjct: 343 KAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALP---SPAAVPPPAPGTPTG 399

Query: 568 CQDLIVPEQCRCADTRPGSEQPPLGGAASPEVLA---------PVSKEAADLAPTGPSPR 618
                     +     P +    +    +P VLA         P + +   L P     R
Sbjct: 400 LPKGAAGAVTQSLSRTPTATTSGIRATLTPTVLAPRLPQPPQNPTNIQNFQLPPGMVLVR 459

Query: 619 PGPGLLLDVCTKDLADAPAEELQEKGSPAGPPPSQGQPAARPPKEV 664
              G LL +  + LA   A+   +  +   P P+   P + PP ++
Sbjct: 460 SENGQLLMIPQQALAQMQAQAHAQPQTTMAPRPA--TPTSAPPVQI 503


>gi|239508790 PREDICTED: hypothetical protein, partial [Homo sapiens]
          Length = 490

 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 72/279 (25%), Positives = 101/279 (36%), Gaps = 32/279 (11%)

Query: 923  RPIQSSLTKAALSRPI-VPKVL------PPQATSHLASAIDLAATSAGILSGNPLPALDT 975
            RP+ S L     S P  VP +L      P   +S  +    L +    +LSG P P  D 
Sbjct: 104  RPLVSPLLSGVPSPPSDVPSLLSGVPSLPSDVSSPPSDVPSLLSDVPSLLSGVPSPPSDV 163

Query: 976  EGLSGISPLSSDEVTGAISGQDSTGTHQDGDTLPTVGGSDPFVSIPSRPEQEPVADSFQG 1035
                   P    +V   +SG  S          P      P   +PS P   P+      
Sbjct: 164  PSPPSDVPSPPSDVPSLLSGVPS----------PPSDVPSPPSDVPSPPSDVPLLSDVPS 213

Query: 1036 --SSVLSLSELPKAPLQNGLSIPLSSSESSSTRLSPPDVSALLDISLPGPPEDALSQGEP 1093
              S V  LS++P  P  +  S+P      S     P DV +LL   +P PP D     + 
Sbjct: 214  PPSDVPLLSDVPSPP-SDVPSLPSDVPSLSGVPSPPSDVPSLLS-GVPSPPSDISPPSDV 271

Query: 1094 ATHISDSIIEIAISSGQYGEGVPLSPAKLNGSDSS-----KSLPSPSSS-PQPHWIASPT 1147
             + +SD +  +         GVP  P+ +    S        +PSP S  P    + SP 
Sbjct: 272  PSLLSD-VPSLPSDVPSLLSGVPSPPSDVPSLLSDVPSPPSDVPSPPSDIPLLSGVPSPP 330

Query: 1148 HD----PQWYPSDSTDSSLSSLFASFISPEKSRKMLPTP 1182
             D    P   PS  +D  L S   S +S       +P+P
Sbjct: 331  SDVPSPPSDVPSPPSDVPLLSGVPSPLSDVPLLSGVPSP 369



 Score = 38.1 bits (87), Expect = 0.054
 Identities = 81/323 (25%), Positives = 113/323 (34%), Gaps = 69/323 (21%)

Query: 514 PRHQDTGPCLEKTPAEGRDSPTREPG--ALPCACGQLPDLEDELSLLDPLPRYLKSCQDL 571
           P      P L   P+   D P+   G  +LP      P   D  SLL  +P  L      
Sbjct: 102 PHRPLVSPLLSGVPSPPSDVPSLLSGVPSLPSDVSSPPS--DVPSLLSDVPSLLSG---- 155

Query: 572 IVPEQCRCADTRPGSEQPPLGGAASPEVLAPVSKEAADLAPTGPSPRPGPG----LLLDV 627
            VP       + P     P      P +L+ V    +D+ P+ PS  P P     LL DV
Sbjct: 156 -VPSPPSDVPSPPSDVPSPPSDV--PSLLSGVPSPPSDV-PSPPSDVPSPPSDVPLLSDV 211

Query: 628 CTKD-----LADAPAEELQEKGSPAGPPPSQGQPAARPPKEVPASRLAQQLREEGWNLQT 682
            +       L+D P+        P+  P   G P+  PP +VP+                
Sbjct: 212 PSPPSDVPLLSDVPSPPSDVPSLPSDVPSLSGVPS--PPSDVPS---------------- 253

Query: 683 SESLTLAEVYLMMGKPSKLQLEYDWLGPGRQDPRPGSLPTALHK-QRLLSCLLKLISTEV 741
                     L+ G PS          P      P  +P+ L     L S +  L+S   
Sbjct: 254 ----------LLSGVPS----------PPSDISPPSDVPSLLSDVPSLPSDVPSLLSGVP 293

Query: 742 NPKLALEANTISTASVRPAQEEQSMTPPGKVVTVSSRSPRCPRNQASLRSSKTFPPSSAP 801
           +P     ++  S  S  P+      +PP  +  +S   P  P +  S  S    PPS  P
Sbjct: 294 SPP----SDVPSLLSDVPSPPSDVPSPPSDIPLLSG-VPSPPSDVPSPPSDVPSPPSDVP 348

Query: 802 CSSGLRNP--PRPLL--VPGPSS 820
             SG+ +P    PLL  VP P S
Sbjct: 349 LLSGVPSPLSDVPLLSGVPSPPS 371


>gi|156616290 collagen type VI alpha 6 [Homo sapiens]
          Length = 2263

 Score = 48.1 bits (113), Expect = 5e-05
 Identities = 50/157 (31%), Positives = 62/157 (39%), Gaps = 20/157 (12%)

Query: 7    DGGSGEDGLKKL-GKRAADEESLEGE-GAGGADAAEESSGTKRDEKTPRAGADGPPAPPG 64
            +G  G  G +   G R A  + L G+ GA G D++ E     + E+  R G  G P PPG
Sbjct: 1487 EGSQGSPGKRGTPGDRGA--KGLRGDPGAPGVDSSIEGPTGLKGERG-RQGRRGWPGPPG 1543

Query: 65   APQAPSPPQGSPQDQHHFLRSSVRPQSKRPRKDPPSAVGS-GNAGGSGPRG----KGAEG 119
             P +            H  R    PQ       P    GS G  G  GPRG    KG +G
Sbjct: 1544 TPGSRRKTAA------HGRRGHTGPQGTAGIPGPDGLEGSLGLKGPQGPRGEAGVKGEKG 1597

Query: 120  GGSSSGNVSGVAPAAPAGGSRSSSRNLGSSGGEKEEG 156
            G  S G      P    GG   +   LGS G + E G
Sbjct: 1598 GVGSKGPQGPPGP----GGEAGNQGRLGSQGNKGEPG 1630


>gi|112734870 hypothetical protein LOC57648 [Homo sapiens]
          Length = 1094

 Score = 48.1 bits (113), Expect = 5e-05
 Identities = 52/189 (27%), Positives = 71/189 (37%), Gaps = 20/189 (10%)

Query: 473 VGRPPPAADALQSSGESSPESAPGEGAALSLSSPDAPDRPPPRHQDTGPCLEKTPAEGRD 532
           V  P PA  +      SSP ++     AL +  P +PD PPP      P     P     
Sbjct: 797 VASPEPAGPSGSPELVSSPAASSSSATALQIQPPGSPD-PPPAPPAPAPA-SSAPGHVAK 854

Query: 533 SPTREPGALPCACGQLPDLED-ELSLLDPLPRYLKSCQDLIVPEQCRCADTRPGSEQPPL 591
            P +EP  + C+ G  P  ED    L+ P          L+   + R      G+  P L
Sbjct: 855 LPQKEP--VGCSKGGGPPREDVGAPLVTP---------SLLQMVRLRSVGAPGGAPTPAL 903

Query: 592 GGAASPEVLAPVSKEAADLAPTGPSPRPGPGLLLDVCTKDLADAPAEELQEKGSPAGPPP 651
           G +A  + L       A      P P P  GL   V  K  + A +E L     P GPP 
Sbjct: 904 GPSAPQKPLRRALSGRA-----SPVPAPSSGLHAAVRLKACSLAASEGL-SSAQPNGPPE 957

Query: 652 SQGQPAARP 660
           ++ +P   P
Sbjct: 958 AEPRPPQSP 966



 Score = 42.0 bits (97), Expect = 0.004
 Identities = 89/340 (26%), Positives = 120/340 (35%), Gaps = 65/340 (19%)

Query: 476 PPPAADALQSSGESSPESAPGEGAALSLSSPDAPDRPPPRHQDTGPCLEKTPAEGRDS-- 533
           P PAA AL     ++P   PG      +S+ DA  + PP  Q T   L+++P   +D   
Sbjct: 680 PNPAAPAL-----AAPAVVPGP-----VSTTDASPQSPPTPQTTLTPLQESPVISKDQSP 729

Query: 534 -------------PTREPGALPCACGQLPDLEDELSLLD--PLPRYLKSCQDLIVPEQCR 578
                        PT++P  +  A       E+ L   +  P P      QDL +     
Sbjct: 730 PPSPPPSYHPPPPPTKKPEVVVEAPSASETAEEPLQDPNWPPPPPPAPEEQDLSM----- 784

Query: 579 CADTRPGSEQPPLGGAASPEVLAPVSKEAADLAPTGPSPRPGPGLLLDVCTKDLADAPAE 638
            AD  P  E       ASPE             P GPS  P    L+       + A A 
Sbjct: 785 -ADFPPPEEA--FFSVASPE-------------PAGPSGSPE---LVSSPAASSSSATAL 825

Query: 639 ELQEKGSPAGPPPSQGQPAARPPKEVPAS----RLAQQLREEGWNLQTSESLTLAEVYLM 694
           ++Q  GSP  PPP+       PP   PAS     +A+  ++E             +V   
Sbjct: 826 QIQPPGSP-DPPPA-------PPAPAPASSAPGHVAKLPQKEPVGCSKGGGPPREDVGAP 877

Query: 695 MGKPSKLQL-EYDWLGPGRQDPRPGSLPTALHKQRLLSCLLKLISTEVNPKLALEANTIS 753
           +  PS LQ+     +G     P P   P+A  K  L   L    S    P   L A    
Sbjct: 878 LVTPSLLQMVRLRSVGAPGGAPTPALGPSAPQKP-LRRALSGRASPVPAPSSGLHAAVRL 936

Query: 754 TASVRPAQEEQSMTPPGKVVTVSSRSPRCPRNQASLRSSK 793
            A    A E  S   P        R P+ P + AS   SK
Sbjct: 937 KACSLAASEGLSSAQPNGPPEAEPRPPQSPASTASFIFSK 976



 Score = 35.8 bits (81), Expect = 0.27
 Identities = 156/744 (20%), Positives = 245/744 (32%), Gaps = 123/744 (16%)

Query: 465  RSGAEGKGVGRPPPAADALQ-SSGESSPESAPGEGAALSLSSPDAP-------DRPPPRH 516
            R+  E  G  R P A DA++  + +  P    G GA +SL + +A        +    RH
Sbjct: 236  RNEREAPGTPRAPGARDAVRIPTVDGRPRGTSGMGARVSLQALEAEAEAGAETEAMLQRH 295

Query: 517  QDTGPCLEKTPAEGRDSPTREPGALPCACGQLPDLEDELSLLDPLPRYLKSCQDLIVPEQ 576
             D           GR + TR P         +P L       +PL   +      I P+ 
Sbjct: 296  IDR--VYRDDTFVGRSTGTRAPPLTRPMSLAVPGLTGGAGPAEPLSPAMS-----ISPQA 348

Query: 577  CRCADTRPGSEQPPLG-----GAASPEVLAPVSKEAADLAP----------TGPSPRPG- 620
               +   P +  PP       G  S   L+  S  +A  A           + P PR   
Sbjct: 349  TYLSKLIPHAVLPPTVDVVALGRCSLRTLSRCSLHSASPASVRSLGRFSSVSSPQPRSRH 408

Query: 621  PGLLLDVCT----KDLADAPAEELQEKGSPAGPPPSQ-GQPAARPPKEVPASRLAQQLRE 675
            P    D  +     D   +    L  KG   G P S     +  PP +  + R +     
Sbjct: 409  PSSSSDTWSHSQSSDTIVSDGSTLSSKGGSEGQPESSTASNSVVPPPQGGSGRGSPS--- 465

Query: 676  EGWNLQTSESLTLAEVYLMMGKPSKLQLEYDWLGPGRQDPRPGSLPTALHKQRLLSC--- 732
             G   + S++L++     + G+   L+         ++ P P     +LH++ L      
Sbjct: 466  GGSTAEASDTLSIRSSGQLSGRSVSLRKL-------KRPPPPPRRTHSLHQRGLAVPDGP 518

Query: 733  --LLKLISTEVNPKLALEANTIST----ASVRPAQEEQSMTPPGKVVTVSSRSPRCPRNQ 786
              L      +  P+L     T  +    A+  P     S  P G     S R PR P   
Sbjct: 519  LGLPPKPERKQQPQLPRPPTTGGSEGAGAAPCPPNPANSWVP-GLSPGGSRRPPRSPERT 577

Query: 787  ASLRS-------SKTFPP---SSAPCSSGLRNPPRPLLVPGPSSTGSNDSDG--GLFAVP 834
             S  S       + T PP   +  P S G   PP+P  V    S G++ S     L +  
Sbjct: 578  LSPSSGYSSQSGTPTLPPKGLAGPPASPGKAQPPKPERVTSLRSPGASVSSSLTSLCSSS 637

Query: 835  TTLPPNSRHGKLFSPSKEAELTFRQHLNSISMQSDFFLPKPRKLRNRHLRKPLVVQRTLL 894
            +   P+ R G    P     L  R  +         F P P K R+ +   P +    ++
Sbjct: 638  SDPAPSDRSG----PQILTPLGDRFVIPPHPKVPAPFSPPPSKPRSPNPAAPALAAPAVV 693

Query: 895  PRPSENQSHNVCSFSILSNSSVTGRGSFRPIQSS--LTKAALSRPIVPKVLPPQATSHLA 952
            P P       V +      S  T + +  P+Q S  ++K     P  P    P       
Sbjct: 694  PGP-------VSTTDASPQSPPTPQTTLTPLQESPVISKDQSPPPSPPPSYHPPPPPTKK 746

Query: 953  SAIDLAATSAGILSGNPL----------PALDTEGLSGISPLSSDEVTGAISGQDSTGTH 1002
              + + A SA   +  PL          PA + + LS       +E   +++  +  G  
Sbjct: 747  PEVVVEAPSASETAEEPLQDPNWPPPPPPAPEEQDLSMADFPPPEEAFFSVASPEPAGP- 805

Query: 1003 QDGDTLPTVGGSDPFVSIPSRPEQEPVADSFQGSSVLSLSELPKAPLQNGLSIPLSSSES 1062
                      GS   VS P+       A   Q          P AP       P SS+  
Sbjct: 806  ---------SGSPELVSSPAASSSSATALQIQPPGSPDPPPAPPAP------APASSAPG 850

Query: 1063 SSTRLSPPDVSALLDISLPGPPEDALSQGEPATHISDSIIEI----------AISSGQYG 1112
               +L  P    +      GPP + +     A  ++ S++++             +   G
Sbjct: 851  HVAKL--PQKEPVGCSKGGGPPREDVG----APLVTPSLLQMVRLRSVGAPGGAPTPALG 904

Query: 1113 EGVPLSPAKLNGSDSSKSLPSPSS 1136
               P  P +   S  +  +P+PSS
Sbjct: 905  PSAPQKPLRRALSGRASPVPAPSS 928



 Score = 32.3 bits (72), Expect = 3.0
 Identities = 26/80 (32%), Positives = 32/80 (40%), Gaps = 19/80 (23%)

Query: 38  AAEESSGTKRDEKTPRAGADGPPAPPGAPQAPSPPQGSPQDQHHFLRSSVRPQSKRPRKD 97
           AA  SS T    + P     G P PP AP AP+P   +P              +K P+K+
Sbjct: 816 AASSSSATALQIQPP-----GSPDPPPAPPAPAPASSAPGH-----------VAKLPQKE 859

Query: 98  PPSAVGSGNAGGSGPRGKGA 117
           P   VG    GG      GA
Sbjct: 860 P---VGCSKGGGPPREDVGA 876


>gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Homo
            sapiens]
          Length = 1818

 Score = 47.8 bits (112), Expect = 7e-05
 Identities = 44/165 (26%), Positives = 59/165 (35%), Gaps = 18/165 (10%)

Query: 8    GGSGEDGLKKLGKRAADEESLEGEGAGGADAAEESSGTKRDEKTPRAGADGPPAPPG--A 65
            G +GE G + +  +          G  G+  A   +G    + T  +G DGPP PPG   
Sbjct: 874  GANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGT--SGGDGPPGPPGERG 931

Query: 66   PQAPSPPQGSPQDQ-------------HHFLRSSVRPQSKRPRKDPPSAVG-SGNAGGSG 111
            PQ P  P G P  +             H   R     Q K     P   VG  G  G +G
Sbjct: 932  PQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETG 991

Query: 112  PRGKGAEGGGSSSGNVSGVAPAAPAGGSRSSSRNLGSSGGEKEEG 156
            P G+    G        G+  AA   G++      G SG +   G
Sbjct: 992  PIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAG 1036



 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 56/164 (34%), Positives = 61/164 (37%), Gaps = 26/164 (15%)

Query: 7   DGGSGEDGLKKLGKRAADEESLEGEGAGGADAAEESSGTKRDEKTP-RAGADGPPAPPG- 64
           DG  GEDG  ++G R          G  G        GT      P  AG DGPP P G 
Sbjct: 642 DGMRGEDG--EIGPRGLP-------GEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGN 692

Query: 65  -APQA-PSPP--QGSPQDQHHFLRSSVRPQSKRPRKDPPSAVG-SGNAGGSGPRG-KGAE 118
             PQ  P PP  QG+P  Q   L     P      K P    G +G  G  GP G  G E
Sbjct: 693 MGPQGEPGPPGQQGNPGPQG--LPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKE 750

Query: 119 GGGSSSGNVSGVAPAAPAG--GSR-----SSSRNLGSSGGEKEE 155
           G     G +    P  P G  G R        R L  S GEK E
Sbjct: 751 GQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGE 794



 Score = 43.9 bits (102), Expect = 0.001
 Identities = 39/152 (25%), Positives = 58/152 (38%), Gaps = 21/152 (13%)

Query: 6    GDGGSGEDGLKKLGKRAADEESLEGEGAGGADAAEESSGTKRDE-KTPRAGADGPPAPPG 64
            GDG  G  G + +  +  DE +    G  G    +   G   ++ +    G  GPP PPG
Sbjct: 1178 GDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPG 1237

Query: 65   APQAPSPPQGSPQDQHHFLRSSVRPQSKRPRKDPPSAVGSGNAGGSGPRGKGAEGGGSSS 124
             P+ P  P G+   Q                  PP +VGS   GG G +G+  E G    
Sbjct: 1238 -PRGPQGPNGADGPQ-----------------GPPGSVGS--VGGVGEKGEPGEAGNPGP 1277

Query: 125  GNVSGVAPAAPAGGSRSSSRNLGSSGGEKEEG 156
               +GV       G +  +   G++G    +G
Sbjct: 1278 PGEAGVGGPKGERGEKGEAGPPGAAGPPGAKG 1309



 Score = 43.9 bits (102), Expect = 0.001
 Identities = 41/156 (26%), Positives = 58/156 (37%), Gaps = 15/156 (9%)

Query: 8    GGSGEDGLKKLGKRAADEESLEGEGAGGADAAEESSGTKRDEKTP-RAGADGPP---APP 63
            G  GE G +    +          G  G +      G   ++  P  AG DGPP    PP
Sbjct: 1390 GAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPP 1449

Query: 64   GAPQAPSPPQGSPQDQHHFLRSSVRPQSKRPRKDPPSAVGSGNAGGSGPRGK-GAEGGGS 122
            G P     P    +  H  L   + P  ++  K        G+ G  G +G  GA+G G 
Sbjct: 1450 GLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEK--------GDRGLPGTQGSPGAKGDGG 1501

Query: 123  SSGNVSGVAPAAPAG--GSRSSSRNLGSSGGEKEEG 156
              G    + P  P G  G +    N GS+G   ++G
Sbjct: 1502 IPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKG 1537



 Score = 41.2 bits (95), Expect = 0.006
 Identities = 40/134 (29%), Positives = 52/134 (38%), Gaps = 19/134 (14%)

Query: 32   GAGGADAAEESSGTKRDEKTPRAGADGPPAPPGAPQAPSPPQGSPQDQHHFLRSSVRPQS 91
            GA GA+  +   G K +     AGA+GPP   G P  P  P G P  +   LR    P  
Sbjct: 1378 GAAGAEGRQGEKGAKGE-----AGAEGPPGKTG-PVGPQGPAGKPGPEG--LRGIPGPVG 1429

Query: 92   KRPRKDPPSAVGSGNAGGSGPRG----KGAEGGGSSSGNVSGVAPAAPAG-----GSRSS 142
            ++    P +A   G  G  GP G    KG  G     G+   +    P G     G R  
Sbjct: 1430 EQGL--PGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGL 1487

Query: 143  SRNLGSSGGEKEEG 156
                GS G + + G
Sbjct: 1488 PGTQGSPGAKGDGG 1501



 Score = 40.4 bits (93), Expect = 0.011
 Identities = 31/133 (23%), Positives = 43/133 (32%), Gaps = 4/133 (3%)

Query: 30  GEGAGGADAAEESSGTKRDEKTPRAGADGPPAPPGAPQAPSPPQGSPQDQHHFLRSSVRP 89
           G+G+ G   + + +  +   +  R    GPP P G    P P  G              P
Sbjct: 513 GDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGP 572

Query: 90  QSKRPRKDPPSAVGS----GNAGGSGPRGKGAEGGGSSSGNVSGVAPAAPAGGSRSSSRN 145
           Q  R  + PP   G     G  G  G RG   E G        G+       G R     
Sbjct: 573 QGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGP 632

Query: 146 LGSSGGEKEEGKK 158
            G  G   ++G +
Sbjct: 633 QGPPGPPGDDGMR 645



 Score = 38.1 bits (87), Expect = 0.054
 Identities = 32/108 (29%), Positives = 40/108 (37%), Gaps = 28/108 (25%)

Query: 32   GAGGADAAEESSGTKRDEKTPRAGADGPPAPPGAPQAPSPPQGSPQDQHHFLRSSVRPQS 91
            G  G    +   G K ++  P  G  GPP P G    P PP                   
Sbjct: 1333 GEPGPAGQDGVGGDKGEDGDP--GQPGPPGPSGEAGPPGPPG------------------ 1372

Query: 92   KRPRKDPPSAVGS-GNAGGSGPRGK-GAEGGGSSSGNVSGVAPAAPAG 137
               ++ PP A G+ G  G  G +G+ GAEG     G    V P  PAG
Sbjct: 1373 ---KRGPPGAAGAEGRQGEKGAKGEAGAEG---PPGKTGPVGPQGPAG 1414



 Score = 37.4 bits (85), Expect = 0.092
 Identities = 40/147 (27%), Positives = 50/147 (34%), Gaps = 22/147 (14%)

Query: 25   EESLEGEGAGGADAAEESSGTKRDEKTPRAGADGPPAPPGAPQAPSPP-----QGSPQDQ 79
            E+   GE        E   G  + E+  + G  GPP   G P A  PP     +G+P   
Sbjct: 1265 EKGEPGEAGNPGPPGEAGVGGPKGERGEK-GEAGPPGAAGPPGAKGPPGDDGPKGNPGPV 1323

Query: 80   HHFLRSSVRPQSKRPRKDPPSA----VGS-----GNAGGSGPRGKGAEGGGSSSGNVSGV 130
                     P    P  +P  A    VG      G+ G  GP G   E G        G 
Sbjct: 1324 GF-------PGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGP 1376

Query: 131  APAAPAGGSRSSSRNLGSSGGEKEEGK 157
              AA A G +      G +G E   GK
Sbjct: 1377 PGAAGAEGRQGEKGAKGEAGAEGPPGK 1403



 Score = 36.2 bits (82), Expect = 0.20
 Identities = 44/155 (28%), Positives = 57/155 (36%), Gaps = 21/155 (13%)

Query: 8    GGSGEDGLKKLGKRAADEESLEGEGAGGADAAEESSGTKRDEKTP-RAGADGPPAPPGAP 66
            G  G  GLK        E      G  G+     S+GT      P R G  GPP P G  
Sbjct: 1048 GAQGAPGLK------GGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEK 1101

Query: 67   QAPSP--PQGSPQDQHHFLRSSVRPQSKRPRKDPPSAVGSGNAGGSGPRGK-GAEGGGSS 123
             AP    PQG           + R   + P   P  A  +G+ G  G +G+ G  G   S
Sbjct: 1102 GAPGEKGPQG----------PAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGS 1151

Query: 124  SGNVSGVAPAAPAGGSRSSSRNLGSSGGEKEEGKK 158
             G+     P  P  G +      G +GG+ E G +
Sbjct: 1152 KGDKGENGPPGPP-GLQGPVGAPGIAGGDGEPGPR 1185



 Score = 34.7 bits (78), Expect = 0.60
 Identities = 48/188 (25%), Positives = 59/188 (31%), Gaps = 31/188 (16%)

Query: 6   GDGGSGEDGLKKLGKRAADEESLEGEGAGGADAAEESSG-------TKRDEKTPRAGADG 58
           G G  GE G K  G+ A  E  +  EG  G        G       T         G  G
Sbjct: 430 GHGAYGEKGQK--GEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPG 487

Query: 59  PPAPPGAPQAPSPP---------------QGSPQDQHHFLRSSVRPQSKRPRKDPPSAVG 103
            P  PGA   P PP               +G           ++  Q++   + PP  +G
Sbjct: 488 RPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMG 547

Query: 104 ----SGNAGGSGPRGKGAEGGGSSSGNVSGV-APAAPAG--GSRSSSRNLGSSGGEKEEG 156
                G  GG G  G   E G        GV  P  P G  G R      G  G   E G
Sbjct: 548 LTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPG 607

Query: 157 KKVRRQWE 164
            K  R ++
Sbjct: 608 AKGDRGFD 615



 Score = 32.3 bits (72), Expect = 3.0
 Identities = 44/170 (25%), Positives = 61/170 (35%), Gaps = 31/170 (18%)

Query: 8    GGSGEDGLK-KLGKRAADEESLEGE----GAGGADAAEESSGTKRDEKTPRAGADGPPAP 62
            G  G+DGL    G+R   E   +G+    G GG    +  +G     +T   G  G P P
Sbjct: 949  GPPGKDGLPGHPGQRG--ETGFQGKTGPPGPGGVVGPQGPTG-----ETGPIGERGHPGP 1001

Query: 63   PGAPQAPSPPQGSPQDQHHFLRSSVRPQSKRPRKDP------------PSAVGS-GNAGG 109
            PG P     P  + ++     +    PQ    +  P            P A G+ G  GG
Sbjct: 1002 PGPPGEQGLPGAAGKEG---AKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGG 1058

Query: 110  SGPRG-KGAEGGGSSSGNVSGVAPAAPAG--GSRSSSRNLGSSGGEKEEG 156
             GP+G  G  G     G+     P    G  G +      G  G   E+G
Sbjct: 1059 EGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKG 1108



 Score = 30.8 bits (68), Expect = 8.6
 Identities = 25/78 (32%), Positives = 27/78 (34%), Gaps = 7/78 (8%)

Query: 467 GAEGK----GVGRPPPAADALQSSGESSPESAPGEGAALSLSSPDAPDRPPPRHQDTG-P 521
           GA G+    GV  PP     +   GE  P    G      L  P  P  PP      G P
Sbjct: 673 GAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKP 732

Query: 522 CLEKTPAEGRDSPTREPG 539
            L   P  G D P   PG
Sbjct: 733 GLAGLP--GADGPPGHPG 748


>gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Homo
           sapiens]
          Length = 1767

 Score = 47.8 bits (112), Expect = 7e-05
 Identities = 44/165 (26%), Positives = 59/165 (35%), Gaps = 18/165 (10%)

Query: 8   GGSGEDGLKKLGKRAADEESLEGEGAGGADAAEESSGTKRDEKTPRAGADGPPAPPG--A 65
           G +GE G + +  +          G  G+  A   +G    + T  +G DGPP PPG   
Sbjct: 823 GANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGT--SGGDGPPGPPGERG 880

Query: 66  PQAPSPPQGSPQDQ-------------HHFLRSSVRPQSKRPRKDPPSAVG-SGNAGGSG 111
           PQ P  P G P  +             H   R     Q K     P   VG  G  G +G
Sbjct: 881 PQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETG 940

Query: 112 PRGKGAEGGGSSSGNVSGVAPAAPAGGSRSSSRNLGSSGGEKEEG 156
           P G+    G        G+  AA   G++      G SG +   G
Sbjct: 941 PIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAG 985



 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 56/164 (34%), Positives = 61/164 (37%), Gaps = 26/164 (15%)

Query: 7   DGGSGEDGLKKLGKRAADEESLEGEGAGGADAAEESSGTKRDEKTP-RAGADGPPAPPG- 64
           DG  GEDG  ++G R          G  G        GT      P  AG DGPP P G 
Sbjct: 591 DGMRGEDG--EIGPRGLP-------GEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGN 641

Query: 65  -APQA-PSPP--QGSPQDQHHFLRSSVRPQSKRPRKDPPSAVG-SGNAGGSGPRG-KGAE 118
             PQ  P PP  QG+P  Q   L     P      K P    G +G  G  GP G  G E
Sbjct: 642 MGPQGEPGPPGQQGNPGPQG--LPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKE 699

Query: 119 GGGSSSGNVSGVAPAAPAG--GSR-----SSSRNLGSSGGEKEE 155
           G     G +    P  P G  G R        R L  S GEK E
Sbjct: 700 GQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGE 743



 Score = 43.9 bits (102), Expect = 0.001
 Identities = 39/152 (25%), Positives = 58/152 (38%), Gaps = 21/152 (13%)

Query: 6    GDGGSGEDGLKKLGKRAADEESLEGEGAGGADAAEESSGTKRDE-KTPRAGADGPPAPPG 64
            GDG  G  G + +  +  DE +    G  G    +   G   ++ +    G  GPP PPG
Sbjct: 1127 GDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPG 1186

Query: 65   APQAPSPPQGSPQDQHHFLRSSVRPQSKRPRKDPPSAVGSGNAGGSGPRGKGAEGGGSSS 124
             P+ P  P G+   Q                  PP +VGS   GG G +G+  E G    
Sbjct: 1187 -PRGPQGPNGADGPQ-----------------GPPGSVGS--VGGVGEKGEPGEAGNPGP 1226

Query: 125  GNVSGVAPAAPAGGSRSSSRNLGSSGGEKEEG 156
               +GV       G +  +   G++G    +G
Sbjct: 1227 PGEAGVGGPKGERGEKGEAGPPGAAGPPGAKG 1258



 Score = 43.9 bits (102), Expect = 0.001
 Identities = 41/156 (26%), Positives = 58/156 (37%), Gaps = 15/156 (9%)

Query: 8    GGSGEDGLKKLGKRAADEESLEGEGAGGADAAEESSGTKRDEKTP-RAGADGPP---APP 63
            G  GE G +    +          G  G +      G   ++  P  AG DGPP    PP
Sbjct: 1339 GAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPP 1398

Query: 64   GAPQAPSPPQGSPQDQHHFLRSSVRPQSKRPRKDPPSAVGSGNAGGSGPRGK-GAEGGGS 122
            G P     P    +  H  L   + P  ++  K        G+ G  G +G  GA+G G 
Sbjct: 1399 GLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEK--------GDRGLPGTQGSPGAKGDGG 1450

Query: 123  SSGNVSGVAPAAPAG--GSRSSSRNLGSSGGEKEEG 156
              G    + P  P G  G +    N GS+G   ++G
Sbjct: 1451 IPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKG 1486



 Score = 41.2 bits (95), Expect = 0.006
 Identities = 40/134 (29%), Positives = 52/134 (38%), Gaps = 19/134 (14%)

Query: 32   GAGGADAAEESSGTKRDEKTPRAGADGPPAPPGAPQAPSPPQGSPQDQHHFLRSSVRPQS 91
            GA GA+  +   G K +     AGA+GPP   G P  P  P G P  +   LR    P  
Sbjct: 1327 GAAGAEGRQGEKGAKGE-----AGAEGPPGKTG-PVGPQGPAGKPGPEG--LRGIPGPVG 1378

Query: 92   KRPRKDPPSAVGSGNAGGSGPRG----KGAEGGGSSSGNVSGVAPAAPAG-----GSRSS 142
            ++    P +A   G  G  GP G    KG  G     G+   +    P G     G R  
Sbjct: 1379 EQGL--PGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGL 1436

Query: 143  SRNLGSSGGEKEEG 156
                GS G + + G
Sbjct: 1437 PGTQGSPGAKGDGG 1450



 Score = 40.4 bits (93), Expect = 0.011
 Identities = 31/133 (23%), Positives = 43/133 (32%), Gaps = 4/133 (3%)

Query: 30  GEGAGGADAAEESSGTKRDEKTPRAGADGPPAPPGAPQAPSPPQGSPQDQHHFLRSSVRP 89
           G+G+ G   + + +  +   +  R    GPP P G    P P  G              P
Sbjct: 462 GDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGP 521

Query: 90  QSKRPRKDPPSAVGS----GNAGGSGPRGKGAEGGGSSSGNVSGVAPAAPAGGSRSSSRN 145
           Q  R  + PP   G     G  G  G RG   E G        G+       G R     
Sbjct: 522 QGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGP 581

Query: 146 LGSSGGEKEEGKK 158
            G  G   ++G +
Sbjct: 582 QGPPGPPGDDGMR 594



 Score = 38.1 bits (87), Expect = 0.054
 Identities = 32/108 (29%), Positives = 40/108 (37%), Gaps = 28/108 (25%)

Query: 32   GAGGADAAEESSGTKRDEKTPRAGADGPPAPPGAPQAPSPPQGSPQDQHHFLRSSVRPQS 91
            G  G    +   G K ++  P  G  GPP P G    P PP                   
Sbjct: 1282 GEPGPAGQDGVGGDKGEDGDP--GQPGPPGPSGEAGPPGPPG------------------ 1321

Query: 92   KRPRKDPPSAVGS-GNAGGSGPRGK-GAEGGGSSSGNVSGVAPAAPAG 137
               ++ PP A G+ G  G  G +G+ GAEG     G    V P  PAG
Sbjct: 1322 ---KRGPPGAAGAEGRQGEKGAKGEAGAEG---PPGKTGPVGPQGPAG 1363



 Score = 37.4 bits (85), Expect = 0.092
 Identities = 40/147 (27%), Positives = 50/147 (34%), Gaps = 22/147 (14%)

Query: 25   EESLEGEGAGGADAAEESSGTKRDEKTPRAGADGPPAPPGAPQAPSPP-----QGSPQDQ 79
            E+   GE        E   G  + E+  + G  GPP   G P A  PP     +G+P   
Sbjct: 1214 EKGEPGEAGNPGPPGEAGVGGPKGERGEK-GEAGPPGAAGPPGAKGPPGDDGPKGNPGPV 1272

Query: 80   HHFLRSSVRPQSKRPRKDPPSA----VGS-----GNAGGSGPRGKGAEGGGSSSGNVSGV 130
                     P    P  +P  A    VG      G+ G  GP G   E G        G 
Sbjct: 1273 GF-------PGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGP 1325

Query: 131  APAAPAGGSRSSSRNLGSSGGEKEEGK 157
              AA A G +      G +G E   GK
Sbjct: 1326 PGAAGAEGRQGEKGAKGEAGAEGPPGK 1352



 Score = 36.2 bits (82), Expect = 0.20
 Identities = 44/155 (28%), Positives = 57/155 (36%), Gaps = 21/155 (13%)

Query: 8    GGSGEDGLKKLGKRAADEESLEGEGAGGADAAEESSGTKRDEKTP-RAGADGPPAPPGAP 66
            G  G  GLK        E      G  G+     S+GT      P R G  GPP P G  
Sbjct: 997  GAQGAPGLK------GGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEK 1050

Query: 67   QAPSP--PQGSPQDQHHFLRSSVRPQSKRPRKDPPSAVGSGNAGGSGPRGK-GAEGGGSS 123
             AP    PQG           + R   + P   P  A  +G+ G  G +G+ G  G   S
Sbjct: 1051 GAPGEKGPQG----------PAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGS 1100

Query: 124  SGNVSGVAPAAPAGGSRSSSRNLGSSGGEKEEGKK 158
             G+     P  P  G +      G +GG+ E G +
Sbjct: 1101 KGDKGENGPPGPP-GLQGPVGAPGIAGGDGEPGPR 1134



 Score = 34.7 bits (78), Expect = 0.60
 Identities = 48/188 (25%), Positives = 59/188 (31%), Gaps = 31/188 (16%)

Query: 6   GDGGSGEDGLKKLGKRAADEESLEGEGAGGADAAEESSG-------TKRDEKTPRAGADG 58
           G G  GE G K  G+ A  E  +  EG  G        G       T         G  G
Sbjct: 379 GHGAYGEKGQK--GEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPG 436

Query: 59  PPAPPGAPQAPSPP---------------QGSPQDQHHFLRSSVRPQSKRPRKDPPSAVG 103
            P  PGA   P PP               +G           ++  Q++   + PP  +G
Sbjct: 437 RPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMG 496

Query: 104 ----SGNAGGSGPRGKGAEGGGSSSGNVSGV-APAAPAG--GSRSSSRNLGSSGGEKEEG 156
                G  GG G  G   E G        GV  P  P G  G R      G  G   E G
Sbjct: 497 LTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPG 556

Query: 157 KKVRRQWE 164
            K  R ++
Sbjct: 557 AKGDRGFD 564



 Score = 32.3 bits (72), Expect = 3.0
 Identities = 44/170 (25%), Positives = 61/170 (35%), Gaps = 31/170 (18%)

Query: 8    GGSGEDGLK-KLGKRAADEESLEGE----GAGGADAAEESSGTKRDEKTPRAGADGPPAP 62
            G  G+DGL    G+R   E   +G+    G GG    +  +G     +T   G  G P P
Sbjct: 898  GPPGKDGLPGHPGQRG--ETGFQGKTGPPGPGGVVGPQGPTG-----ETGPIGERGHPGP 950

Query: 63   PGAPQAPSPPQGSPQDQHHFLRSSVRPQSKRPRKDP------------PSAVGS-GNAGG 109
            PG P     P  + ++     +    PQ    +  P            P A G+ G  GG
Sbjct: 951  PGPPGEQGLPGAAGKEG---AKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGG 1007

Query: 110  SGPRG-KGAEGGGSSSGNVSGVAPAAPAG--GSRSSSRNLGSSGGEKEEG 156
             GP+G  G  G     G+     P    G  G +      G  G   E+G
Sbjct: 1008 EGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKG 1057



 Score = 30.8 bits (68), Expect = 8.6
 Identities = 25/78 (32%), Positives = 27/78 (34%), Gaps = 7/78 (8%)

Query: 467 GAEGK----GVGRPPPAADALQSSGESSPESAPGEGAALSLSSPDAPDRPPPRHQDTG-P 521
           GA G+    GV  PP     +   GE  P    G      L  P  P  PP      G P
Sbjct: 622 GAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKP 681

Query: 522 CLEKTPAEGRDSPTREPG 539
            L   P  G D P   PG
Sbjct: 682 GLAGLP--GADGPPGHPG 697


>gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Homo
            sapiens]
          Length = 1806

 Score = 47.8 bits (112), Expect = 7e-05
 Identities = 44/165 (26%), Positives = 59/165 (35%), Gaps = 18/165 (10%)

Query: 8    GGSGEDGLKKLGKRAADEESLEGEGAGGADAAEESSGTKRDEKTPRAGADGPPAPPG--A 65
            G +GE G + +  +          G  G+  A   +G    + T  +G DGPP PPG   
Sbjct: 862  GANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGT--SGGDGPPGPPGERG 919

Query: 66   PQAPSPPQGSPQDQ-------------HHFLRSSVRPQSKRPRKDPPSAVG-SGNAGGSG 111
            PQ P  P G P  +             H   R     Q K     P   VG  G  G +G
Sbjct: 920  PQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETG 979

Query: 112  PRGKGAEGGGSSSGNVSGVAPAAPAGGSRSSSRNLGSSGGEKEEG 156
            P G+    G        G+  AA   G++      G SG +   G
Sbjct: 980  PIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAG 1024



 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 56/164 (34%), Positives = 61/164 (37%), Gaps = 26/164 (15%)

Query: 7   DGGSGEDGLKKLGKRAADEESLEGEGAGGADAAEESSGTKRDEKTP-RAGADGPPAPPG- 64
           DG  GEDG  ++G R          G  G        GT      P  AG DGPP P G 
Sbjct: 630 DGMRGEDG--EIGPRGLP-------GEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGN 680

Query: 65  -APQA-PSPP--QGSPQDQHHFLRSSVRPQSKRPRKDPPSAVG-SGNAGGSGPRG-KGAE 118
             PQ  P PP  QG+P  Q   L     P      K P    G +G  G  GP G  G E
Sbjct: 681 MGPQGEPGPPGQQGNPGPQG--LPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKE 738

Query: 119 GGGSSSGNVSGVAPAAPAG--GSR-----SSSRNLGSSGGEKEE 155
           G     G +    P  P G  G R        R L  S GEK E
Sbjct: 739 GQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGE 782



 Score = 43.9 bits (102), Expect = 0.001
 Identities = 39/152 (25%), Positives = 58/152 (38%), Gaps = 21/152 (13%)

Query: 6    GDGGSGEDGLKKLGKRAADEESLEGEGAGGADAAEESSGTKRDE-KTPRAGADGPPAPPG 64
            GDG  G  G + +  +  DE +    G  G    +   G   ++ +    G  GPP PPG
Sbjct: 1166 GDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPG 1225

Query: 65   APQAPSPPQGSPQDQHHFLRSSVRPQSKRPRKDPPSAVGSGNAGGSGPRGKGAEGGGSSS 124
             P+ P  P G+   Q                  PP +VGS   GG G +G+  E G    
Sbjct: 1226 -PRGPQGPNGADGPQ-----------------GPPGSVGS--VGGVGEKGEPGEAGNPGP 1265

Query: 125  GNVSGVAPAAPAGGSRSSSRNLGSSGGEKEEG 156
               +GV       G +  +   G++G    +G
Sbjct: 1266 PGEAGVGGPKGERGEKGEAGPPGAAGPPGAKG 1297



 Score = 43.9 bits (102), Expect = 0.001
 Identities = 41/156 (26%), Positives = 58/156 (37%), Gaps = 15/156 (9%)

Query: 8    GGSGEDGLKKLGKRAADEESLEGEGAGGADAAEESSGTKRDEKTP-RAGADGPP---APP 63
            G  GE G +    +          G  G +      G   ++  P  AG DGPP    PP
Sbjct: 1378 GAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPP 1437

Query: 64   GAPQAPSPPQGSPQDQHHFLRSSVRPQSKRPRKDPPSAVGSGNAGGSGPRGK-GAEGGGS 122
            G P     P    +  H  L   + P  ++  K        G+ G  G +G  GA+G G 
Sbjct: 1438 GLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEK--------GDRGLPGTQGSPGAKGDGG 1489

Query: 123  SSGNVSGVAPAAPAG--GSRSSSRNLGSSGGEKEEG 156
              G    + P  P G  G +    N GS+G   ++G
Sbjct: 1490 IPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKG 1525



 Score = 41.2 bits (95), Expect = 0.006
 Identities = 40/134 (29%), Positives = 52/134 (38%), Gaps = 19/134 (14%)

Query: 32   GAGGADAAEESSGTKRDEKTPRAGADGPPAPPGAPQAPSPPQGSPQDQHHFLRSSVRPQS 91
            GA GA+  +   G K +     AGA+GPP   G P  P  P G P  +   LR    P  
Sbjct: 1366 GAAGAEGRQGEKGAKGE-----AGAEGPPGKTG-PVGPQGPAGKPGPEG--LRGIPGPVG 1417

Query: 92   KRPRKDPPSAVGSGNAGGSGPRG----KGAEGGGSSSGNVSGVAPAAPAG-----GSRSS 142
            ++    P +A   G  G  GP G    KG  G     G+   +    P G     G R  
Sbjct: 1418 EQGL--PGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGL 1475

Query: 143  SRNLGSSGGEKEEG 156
                GS G + + G
Sbjct: 1476 PGTQGSPGAKGDGG 1489



 Score = 40.4 bits (93), Expect = 0.011
 Identities = 31/133 (23%), Positives = 43/133 (32%), Gaps = 4/133 (3%)

Query: 30  GEGAGGADAAEESSGTKRDEKTPRAGADGPPAPPGAPQAPSPPQGSPQDQHHFLRSSVRP 89
           G+G+ G   + + +  +   +  R    GPP P G    P P  G              P
Sbjct: 501 GDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGP 560

Query: 90  QSKRPRKDPPSAVGS----GNAGGSGPRGKGAEGGGSSSGNVSGVAPAAPAGGSRSSSRN 145
           Q  R  + PP   G     G  G  G RG   E G        G+       G R     
Sbjct: 561 QGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGP 620

Query: 146 LGSSGGEKEEGKK 158
            G  G   ++G +
Sbjct: 621 QGPPGPPGDDGMR 633



 Score = 38.1 bits (87), Expect = 0.054
 Identities = 32/108 (29%), Positives = 40/108 (37%), Gaps = 28/108 (25%)

Query: 32   GAGGADAAEESSGTKRDEKTPRAGADGPPAPPGAPQAPSPPQGSPQDQHHFLRSSVRPQS 91
            G  G    +   G K ++  P  G  GPP P G    P PP                   
Sbjct: 1321 GEPGPAGQDGVGGDKGEDGDP--GQPGPPGPSGEAGPPGPPG------------------ 1360

Query: 92   KRPRKDPPSAVGS-GNAGGSGPRGK-GAEGGGSSSGNVSGVAPAAPAG 137
               ++ PP A G+ G  G  G +G+ GAEG     G    V P  PAG
Sbjct: 1361 ---KRGPPGAAGAEGRQGEKGAKGEAGAEG---PPGKTGPVGPQGPAG 1402



 Score = 37.4 bits (85), Expect = 0.092
 Identities = 40/147 (27%), Positives = 50/147 (34%), Gaps = 22/147 (14%)

Query: 25   EESLEGEGAGGADAAEESSGTKRDEKTPRAGADGPPAPPGAPQAPSPP-----QGSPQDQ 79
            E+   GE        E   G  + E+  + G  GPP   G P A  PP     +G+P   
Sbjct: 1253 EKGEPGEAGNPGPPGEAGVGGPKGERGEK-GEAGPPGAAGPPGAKGPPGDDGPKGNPGPV 1311

Query: 80   HHFLRSSVRPQSKRPRKDPPSA----VGS-----GNAGGSGPRGKGAEGGGSSSGNVSGV 130
                     P    P  +P  A    VG      G+ G  GP G   E G        G 
Sbjct: 1312 GF-------PGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGP 1364

Query: 131  APAAPAGGSRSSSRNLGSSGGEKEEGK 157
              AA A G +      G +G E   GK
Sbjct: 1365 PGAAGAEGRQGEKGAKGEAGAEGPPGK 1391



 Score = 36.2 bits (82), Expect = 0.20
 Identities = 44/155 (28%), Positives = 57/155 (36%), Gaps = 21/155 (13%)

Query: 8    GGSGEDGLKKLGKRAADEESLEGEGAGGADAAEESSGTKRDEKTP-RAGADGPPAPPGAP 66
            G  G  GLK        E      G  G+     S+GT      P R G  GPP P G  
Sbjct: 1036 GAQGAPGLK------GGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEK 1089

Query: 67   QAPSP--PQGSPQDQHHFLRSSVRPQSKRPRKDPPSAVGSGNAGGSGPRGK-GAEGGGSS 123
             AP    PQG           + R   + P   P  A  +G+ G  G +G+ G  G   S
Sbjct: 1090 GAPGEKGPQG----------PAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGS 1139

Query: 124  SGNVSGVAPAAPAGGSRSSSRNLGSSGGEKEEGKK 158
             G+     P  P  G +      G +GG+ E G +
Sbjct: 1140 KGDKGENGPPGPP-GLQGPVGAPGIAGGDGEPGPR 1173



 Score = 34.7 bits (78), Expect = 0.60
 Identities = 48/188 (25%), Positives = 59/188 (31%), Gaps = 31/188 (16%)

Query: 6   GDGGSGEDGLKKLGKRAADEESLEGEGAGGADAAEESSG-------TKRDEKTPRAGADG 58
           G G  GE G K  G+ A  E  +  EG  G        G       T         G  G
Sbjct: 418 GHGAYGEKGQK--GEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPG 475

Query: 59  PPAPPGAPQAPSPP---------------QGSPQDQHHFLRSSVRPQSKRPRKDPPSAVG 103
            P  PGA   P PP               +G           ++  Q++   + PP  +G
Sbjct: 476 RPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMG 535

Query: 104 ----SGNAGGSGPRGKGAEGGGSSSGNVSGV-APAAPAG--GSRSSSRNLGSSGGEKEEG 156
                G  GG G  G   E G        GV  P  P G  G R      G  G   E G
Sbjct: 536 LTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPG 595

Query: 157 KKVRRQWE 164
            K  R ++
Sbjct: 596 AKGDRGFD 603



 Score = 32.3 bits (72), Expect = 3.0
 Identities = 44/170 (25%), Positives = 61/170 (35%), Gaps = 31/170 (18%)

Query: 8    GGSGEDGLK-KLGKRAADEESLEGE----GAGGADAAEESSGTKRDEKTPRAGADGPPAP 62
            G  G+DGL    G+R   E   +G+    G GG    +  +G     +T   G  G P P
Sbjct: 937  GPPGKDGLPGHPGQRG--ETGFQGKTGPPGPGGVVGPQGPTG-----ETGPIGERGHPGP 989

Query: 63   PGAPQAPSPPQGSPQDQHHFLRSSVRPQSKRPRKDP------------PSAVGS-GNAGG 109
            PG P     P  + ++     +    PQ    +  P            P A G+ G  GG
Sbjct: 990  PGPPGEQGLPGAAGKEG---AKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGG 1046

Query: 110  SGPRG-KGAEGGGSSSGNVSGVAPAAPAG--GSRSSSRNLGSSGGEKEEG 156
             GP+G  G  G     G+     P    G  G +      G  G   E+G
Sbjct: 1047 EGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKG 1096



 Score = 30.8 bits (68), Expect = 8.6
 Identities = 25/78 (32%), Positives = 27/78 (34%), Gaps = 7/78 (8%)

Query: 467 GAEGK----GVGRPPPAADALQSSGESSPESAPGEGAALSLSSPDAPDRPPPRHQDTG-P 521
           GA G+    GV  PP     +   GE  P    G      L  P  P  PP      G P
Sbjct: 661 GAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKP 720

Query: 522 CLEKTPAEGRDSPTREPG 539
            L   P  G D P   PG
Sbjct: 721 GLAGLP--GADGPPGHPG 736


>gi|48762934 alpha 2 type I collagen [Homo sapiens]
          Length = 1366

 Score = 47.8 bits (112), Expect = 7e-05
 Identities = 50/155 (32%), Positives = 58/155 (37%), Gaps = 30/155 (19%)

Query: 6   GDGGSGEDGLK-KLGKRAADEESLEGEGAGGADAAEESSGTKRDEKTPRAGADGPPAPPG 64
           G G  GE GL+ ++G    D       GA GA  A   +G   D     AGA GP  P G
Sbjct: 653 GKGEKGEPGLRGEIGNPGRDG----ARGAPGAVGAPGPAGATGDRG--EAGAAGPAGPAG 706

Query: 65  APQAPSPPQGSPQDQHHFLRSSVRPQSKRPRKDPPSAVG----SGNAGGSGPRGKGAEGG 120
                  P+GSP +     R  V P        P  A G     G  G  GP  KG  G 
Sbjct: 707 -------PRGSPGE-----RGEVGPAGPNGFAGPAGAAGQPGAKGERGAKGP--KGENGV 752

Query: 121 GSSSGNVSGVAPAAPAG-----GSRSSSRNLGSSG 150
              +G V    PA P G     GSR      G +G
Sbjct: 753 VGPTGPVGAAGPAGPNGPPGPAGSRGDGGPPGMTG 787



 Score = 46.6 bits (109), Expect = 2e-04
 Identities = 45/163 (27%), Positives = 61/163 (37%), Gaps = 18/163 (11%)

Query: 8   GGSGEDGLKKLGKRAADEESLEGEGAGGADAAEESSGTKRDEKTPRAGADGPPAPPG--- 64
           G  G++G K     A    +   +G  GA       G +  +     G  GPP PPG   
Sbjct: 502 GDPGKNGDKGHAGLAGARGAPGPDGNNGAQGPPGPQGVQGGK-----GEQGPPGPPGFQG 556

Query: 65  --APQAPSPPQGSPQDQH-HFLRSSVRPQSKRPRKDPPSAVG----SGNAGGSGPRG-KG 116
              P  P+   G P ++  H       P   R  + PP   G    +G  G  GP G  G
Sbjct: 557 LPGPSGPAGEVGKPGERGLHGEFGLPGPAGPRGERGPPGESGAAGPTGPIGSRGPSGPPG 616

Query: 117 AEGGGSSSGNVSGVAPAAPAG--GSRSSSRNLGSSGGEKEEGK 157
            +G     G V  V  A P+G  G        G  GG+ E+G+
Sbjct: 617 PDGNKGEPGVVGAVGTAGPSGPSGLPGERGAAGIPGGKGEKGE 659



 Score = 44.7 bits (104), Expect = 6e-04
 Identities = 36/119 (30%), Positives = 46/119 (38%), Gaps = 9/119 (7%)

Query: 26  ESLEGEGAGGADAAEESSGTKRDEKTP--RAGADGPPAPPGAPQAPSPP----QGSPQDQ 79
           +SL+ E      A +     +R    P  R G DGP  PPG P  P PP      + Q  
Sbjct: 23  QSLQEETVRKGPAGDRGPRGERGPPGPPGRDGEDGPTGPPGPPGPPGPPGLGGNFAAQYD 82

Query: 80  HHFLRSSVRPQSKRPRKDPPSAVGS-GNAGGSGPRGKGAEGGGSSSGNVSGVAPAAPAG 137
              +     P      + PP A G+ G  G  GP G+  E G +      G  PA P G
Sbjct: 83  GKGVGLGPGPMGLMGPRGPPGAAGAPGPQGFQGPAGEPGEPGQTGPAGARG--PAGPPG 139



 Score = 43.1 bits (100), Expect = 0.002
 Identities = 33/119 (27%), Positives = 43/119 (36%), Gaps = 16/119 (13%)

Query: 54  AGADGPPAPPGAPQAPSPPQGSPQDQHHFLRSSVRPQSKRPRKDPPSAVGS--------- 104
           AG  GP   PG   A   P G  +     LR  +    +   +  P AVG+         
Sbjct: 633 AGPSGPSGLPGERGAAGIPGGKGEKGEPGLRGEIGNPGRDGARGAPGAVGAPGPAGATGD 692

Query: 105 -------GNAGGSGPRGKGAEGGGSSSGNVSGVAPAAPAGGSRSSSRNLGSSGGEKEEG 156
                  G AG +GPRG   E G       +G A  A A G   +    G+ G + E G
Sbjct: 693 RGEAGAAGPAGPAGPRGSPGERGEVGPAGPNGFAGPAGAAGQPGAKGERGAKGPKGENG 751



 Score = 39.7 bits (91), Expect = 0.019
 Identities = 42/167 (25%), Positives = 57/167 (34%), Gaps = 31/167 (18%)

Query: 8   GGSGEDGLKKLGKRAAD----EESLEGE-------GAGGADAAEESSGTKRDEKTP---- 52
           G +G+ G K  G+R A     E  + G        G  G +     +G++ D   P    
Sbjct: 730 GAAGQPGAK--GERGAKGPKGENGVVGPTGPVGAAGPAGPNGPPGPAGSRGDGGPPGMTG 787

Query: 53  ---RAGADGPPAPPGAPQAPSPPQGSPQDQHHFLRSSVRPQSKRPRKDPPSAVGSGNAGG 109
               AG  GPP P G    P PP  + ++             + PR D      +G  G 
Sbjct: 788 FPGAAGRTGPPGPSGISGPPGPPGPAGKE-----------GLRGPRGDQGPVGRTGEVGA 836

Query: 110 SGPRGKGAEGGGSSSGNVSGVAPAAPAGGSRSSSRNLGSSGGEKEEG 156
            GP G   E G S     +G        G   +   LG  G   E G
Sbjct: 837 VGPPGFAGEKGPSGEAGTAGPPGTPGPQGLLGAPGILGLPGSRGERG 883



 Score = 38.9 bits (89), Expect = 0.032
 Identities = 40/142 (28%), Positives = 52/142 (36%), Gaps = 12/142 (8%)

Query: 7    DGGSGEDGLKKLGKRAADEESLEGEGAGGADAAEESSGTK-RDEKTPRAGADGPPAPPGA 65
            DG  G DG            ++   GA GA       G   +       G  GP  P GA
Sbjct: 933  DGPPGRDGQPGHKGERGYPGNIGPVGAAGAPGPHGPVGPAGKHGNRGETGPSGPVGPAGA 992

Query: 66   --PQAPSPPQGSPQDQHHFLRSSVRPQSKRPRKDPPSAVGSGNAGGSGPRGKGAEGGGSS 123
              P+ PS PQG   D+         P  K PR  P     +G  G  G  G   + G  +
Sbjct: 993  VGPRGPSGPQGIRGDKGE-------PGEKGPRGLPGLKGHNGLQGLPGIAGHHGDQG--A 1043

Query: 124  SGNVSGVAPAAPAGGSRSSSRN 145
             G+V    P  PAG S  + ++
Sbjct: 1044 PGSVGPAGPRGPAGPSGPAGKD 1065



 Score = 33.9 bits (76), Expect = 1.0
 Identities = 56/191 (29%), Positives = 64/191 (33%), Gaps = 41/191 (21%)

Query: 3   VKLGDGGSGEDGLKKLGKRAADEESLEGE----GAGGADAAEESSGTKRDEKTPRAGADG 58
           VK   G  GE+G    G+  A    L GE    GA G   A  S G+        AG  G
Sbjct: 197 VKGEPGAPGENGTP--GQTGA--RGLPGERGRVGAPGPAGARGSDGSVGP--VGPAGPIG 250

Query: 59  PPAPPGAPQAPSP-----------PQGSPQDQHHF----LRSSVRPQSKRPRKDPPSAVG 103
              PPG P AP P           P G    +       L   V P           A G
Sbjct: 251 SAGPPGFPGAPGPKGEIGAVGNAGPAGPAGPRGEVGLPGLSGPVGPPGNPGANGLTGAKG 310

Query: 104 S-------GNAGGSGPRG----KGAEGGGSSSGNVSGVAPAAPAG-----GSRSSSRNLG 147
           +       G  G  GPRG     GA G   + G V    PA   G     G   S+   G
Sbjct: 311 AAGLPGVAGAPGLPGPRGIPGPVGAAGATGARGLVGEPGPAGSKGESGNKGEPGSAGPQG 370

Query: 148 SSGGEKEEGKK 158
             G   EEGK+
Sbjct: 371 PPGPSGEEGKR 381



 Score = 33.5 bits (75), Expect = 1.3
 Identities = 38/129 (29%), Positives = 49/129 (37%), Gaps = 25/129 (19%)

Query: 53  RAGADGPPAPPGAP-----QAPSPPQGSPQD---------QHHFLRSSVRPQSKRPR-KD 97
           +AG DG P  PG P       P   +G P           + H     ++ Q   P  K 
Sbjct: 140 KAGEDGHPGKPGRPGERGVVGPQGARGFPGTPGLPGFKGIRGHNGLDGLKGQPGAPGVKG 199

Query: 98  PPSAVG-SGNAGGSGPRG-------KGAEGGGSSSGNVSGVAPAAPAG--GSRSSSRNLG 147
            P A G +G  G +G RG        GA G   + G+   V P  PAG  GS       G
Sbjct: 200 EPGAPGENGTPGQTGARGLPGERGRVGAPGPAGARGSDGSVGPVGPAGPIGSAGPPGFPG 259

Query: 148 SSGGEKEEG 156
           + G + E G
Sbjct: 260 APGPKGEIG 268



 Score = 33.1 bits (74), Expect = 1.7
 Identities = 43/151 (28%), Positives = 49/151 (32%), Gaps = 17/151 (11%)

Query: 8   GGSGEDGLKKLGKRAADEESLEGEGAGGADAAEESSGTKRDEKTPRAGADGPPAPPGAPQ 67
           G  GE GL  L        +    G  GA  A    G         AGA G P P G P 
Sbjct: 280 GPRGEVGLPGLSGPVGPPGNPGANGLTGAKGAAGLPGV--------AGAPGLPGPRGIP- 330

Query: 68  APSPPQGSPQDQHHFLRSSVRPQSKRPRKDPPSAVGS-GNAGGSGPRG-KGAEGGGSSSG 125
            P    G+        R  V        K      G  G+AG  GP G  G EG    +G
Sbjct: 331 GPVGAAGATG-----ARGLVGEPGPAGSKGESGNKGEPGSAGPQGPPGPSGEEGKRGPNG 385

Query: 126 NVSGVAPAAPAGGSRSSSRNLGSSGGEKEEG 156
                 P  P  G R S  + G  G +   G
Sbjct: 386 EAGSAGPPGPP-GLRGSPGSRGLPGADGRAG 415



 Score = 33.1 bits (74), Expect = 1.7
 Identities = 49/178 (27%), Positives = 62/178 (34%), Gaps = 35/178 (19%)

Query: 8   GGSGEDGLKKLGKRAADEESLEGEGAGGADAAEESSGTKRDEKTPRAGADGPPAPPGAPQ 67
           G +G++GL+  G R  D+  +   G  GA      +G K    +  AG  GPP  PG   
Sbjct: 811 GPAGKEGLR--GPRG-DQGPVGRTGEVGAVGPPGFAGEKGP--SGEAGTAGPPGTPGPQG 865

Query: 68  APSPPQ--GSPQDQHHFLRSSVRPQSKRP----------RKDPPSAVGS----------- 104
               P   G P  +       V      P           + PP AVGS           
Sbjct: 866 LLGAPGILGLPGSRGERGLPGVAGAVGEPGPLGIAGPPGARGPPGAVGSPGVNGAPGEAG 925

Query: 105 --GNAGGSGPRGK----GAEGGGSSSGNVSGVAPAAPAGGSRSSSRNLGSSGGEKEEG 156
             GN G  GP G+    G +G     GN+ G   AA A G        G  G   E G
Sbjct: 926 RDGNPGNDGPPGRDGQPGHKGERGYPGNI-GPVGAAGAPGPHGPVGPAGKHGNRGETG 982



 Score = 32.0 bits (71), Expect = 3.9
 Identities = 45/172 (26%), Positives = 62/172 (36%), Gaps = 22/172 (12%)

Query: 8   GGSGEDGLKKLGKRAADE-----ESLEGE-GAGGADAAEESSGT-----KRDEKTPRAGA 56
           G SGE+G +     A          L G  G+ G   A+  +G       R    P AG 
Sbjct: 373 GPSGEEGKRGPNGEAGSAGPPGPPGLRGSPGSRGLPGADGRAGVMGPPGSRGASGP-AGV 431

Query: 57  DGPPAPPGAPQAPS--PPQGSPQDQHHFLRSSVRPQSKRPRKD-------PPSAVGS-GN 106
            GP    G P  P    P+G P    +   +        P  D       P  A G  GN
Sbjct: 432 RGPNGDAGRPGEPGLMGPRGLPGSPGNIGPAGKEGPVGLPGIDGRPGPIGPAGARGEPGN 491

Query: 107 AGGSGPRGKGAEGGGSSSGNVSGVAPAAPAGGSRSSSRNLGSSGGEKEEGKK 158
            G  GP+G   + G +     +G+A A  A G   ++   G  G +  +G K
Sbjct: 492 IGFPGPKGPTGDPGKNGDKGHAGLAGARGAPGPDGNNGAQGPPGPQGVQGGK 543



 Score = 32.0 bits (71), Expect = 3.9
 Identities = 31/106 (29%), Positives = 41/106 (38%), Gaps = 23/106 (21%)

Query: 54  AGADGPPAPPGAPQAPSP--PQGSPQDQHHFLRSSVRPQSKRPRKDPPSAVGSGNAGGSG 111
           AG +GP   PG    P P  P G+  +  +       P  K P  DP      G+AG +G
Sbjct: 462 AGKEGPVGLPGIDGRPGPIGPAGARGEPGNI----GFPGPKGPTGDPGKNGDKGHAGLAG 517

Query: 112 PRGK-GAEGGGSSSGNVSGVAPAAPAGGSRSSSRNLGSSGGEKEEG 156
            RG  G +G   + G      P  P G            GG+ E+G
Sbjct: 518 ARGAPGPDGNNGAQG------PPGPQG----------VQGGKGEQG 547


>gi|19920317 cytoskeleton-associated protein 4 [Homo sapiens]
          Length = 602

 Score = 47.4 bits (111), Expect = 9e-05
 Identities = 41/118 (34%), Positives = 48/118 (40%), Gaps = 26/118 (22%)

Query: 32  GAGGADAAEESSGTKRDEKTPRAGADG-PPAPPGAPQAPSPPQGSPQDQHHFLRSSVRPQ 90
           G G A  +E+ +        P  GAD     PP APQ P PP      QH          
Sbjct: 12  GHGAASPSEKGAH-------PSGGADDVAKKPPPAPQQPPPPPAPHPQQH---------- 54

Query: 91  SKRPRKDPPS-AVGSGNAGGSGPRGKGAEGGGSSSGNVSGVAPAAPAGGSRSSSRNLG 147
              P++ P + A G G   G G    G  G  SSS + S  A AA A  S S SR LG
Sbjct: 55  ---PQQHPQNQAHGKGGHRGGG----GGGGKSSSSSSASAAAAAAAASSSASCSRRLG 105


>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
          Length = 1464

 Score = 47.4 bits (111), Expect = 9e-05
 Identities = 43/150 (28%), Positives = 55/150 (36%), Gaps = 9/150 (6%)

Query: 8   GGSGEDGLK-KLGKRAADEESLEGEGAGGADAAEESSGTKRDEKTPRAGADGPPAPPGAP 66
           G  GE+G   ++G R    E     G  GA     + G   D  T  AG  GP  P G P
Sbjct: 290 GSPGENGAPGQMGPRGLPGE----RGRPGAPGPAGARGN--DGATGAAGPPGPTGPAGPP 343

Query: 67  QAPSPPQGSPQDQHHFLRSSVRPQSKRPRKDPPSAVGSGNAGGSGPRGKGAEGGGSSSGN 126
             P       +      R S  PQ  R    PP   G+  AG +G  G   + G   +  
Sbjct: 344 GFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGA--AGPAGNPGADGQPGAKGANG 401

Query: 127 VSGVAPAAPAGGSRSSSRNLGSSGGEKEEG 156
             G+A A    G+R  S   G  G    +G
Sbjct: 402 APGIAGAPGFPGARGPSGPQGPGGPPGPKG 431



 Score = 45.1 bits (105), Expect = 4e-04
 Identities = 43/157 (27%), Positives = 54/157 (34%), Gaps = 6/157 (3%)

Query: 6   GDGGS-GEDGLKKLGKRAADEESLEGEGAGGADAAEESSGTKRDEKTP-RAGADGPPAPP 63
           GD G+ G+ G       A     +   GA GA  A  S+G       P  AG  GPP P 
Sbjct: 830 GDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPS 889

Query: 64  GAPQAPSPPQGSPQDQHHFLRSSVRPQSKRPRKDPPSAVG----SGNAGGSGPRGKGAEG 119
           G    P PP  + ++     R    P  +     PP   G     G+ G  GP G     
Sbjct: 890 GNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTP 949

Query: 120 GGSSSGNVSGVAPAAPAGGSRSSSRNLGSSGGEKEEG 156
           G        GV       G R      G SG   ++G
Sbjct: 950 GPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQG 986



 Score = 43.5 bits (101), Expect = 0.001
 Identities = 48/159 (30%), Positives = 62/159 (38%), Gaps = 21/159 (13%)

Query: 8   GGSGEDGLKKL-GKR-AADEESLEGE-GAGGADAAEESSGTKRDEKTPRAGADGPPAPPG 64
           G  G  GL+ + G+R AA     +G+ G  G   A+ S G  +D      G  GPP P G
Sbjct: 719 GSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPG--KDGVRGLTGPIGPPGPAG 776

Query: 65  AP-----QAPSPPQGSPQDQHHFLRSSVRPQSKRPRKDPPSAVG-SGNAGGSG-PRGKGA 117
           AP       PS P G           +      R    PP   G +G  G  G P  KG 
Sbjct: 777 APGDKGESGPSGPAGPT--------GARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGE 828

Query: 118 EGGGSSSGNVSGVAPAAPAGGSRSSSRNLGSSGGEKEEG 156
            G   + G+     PA PA G      N+G+ G +   G
Sbjct: 829 PGDAGAKGDAGPPGPAGPA-GPPGPIGNVGAPGAKGARG 866



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 42/136 (30%), Positives = 47/136 (34%), Gaps = 17/136 (12%)

Query: 25   EESLEGE-GAGGADAAEESSGTKRDEKTPRAGADGPPAPPGAPQAPSPPQGSPQDQHHFL 83
            E   EG  GA G+   + S G K D      G  GP  PPGAP AP  P           
Sbjct: 1011 ESGREGAPGAEGSPGRDGSPGAKGDR-----GETGPAGPPGAPGAPGAPGPVGPAGKSGD 1065

Query: 84   RSSVRPQSKRPRKDPPSAVGSGNAGGSGPRGKGAEGGGSSSGNVSG-------VAPAAPA 136
            R    P        P  A   G AG  GPRG   E G      + G         P  P 
Sbjct: 1066 RGETGPAGPAGPVGPVGA--RGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPP 1123

Query: 137  G--GSRSSSRNLGSSG 150
            G  G +  S   G +G
Sbjct: 1124 GSPGEQGPSGASGPAG 1139



 Score = 40.8 bits (94), Expect = 0.008
 Identities = 43/146 (29%), Positives = 54/146 (36%), Gaps = 21/146 (14%)

Query: 32  GAGGADAAEESSGTKRDEKTPR-AGADGPPAPPGAPQA--PSPPQGSPQDQHHFLRSSVR 88
           GA G   +  S G       P  AG DG P PPG P A   +   G P  +         
Sbjct: 536 GAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKG--AAGEPG 593

Query: 89  PQSKRPRKDPPSAVG----SGNAGGSGPRG-------KGAEGGGSSSGNVSGVAPAAPAG 137
              +R    PP AVG     G AG  GP G       +G +G   S G      PA P G
Sbjct: 594 KAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPG 653

Query: 138 -----GSRSSSRNLGSSGGEKEEGKK 158
                G +    +LG+ G     G++
Sbjct: 654 EAGKPGEQGVPGDLGAPGPSGARGER 679



 Score = 40.0 bits (92), Expect = 0.014
 Identities = 36/118 (30%), Positives = 49/118 (41%), Gaps = 19/118 (16%)

Query: 54   AGADGPPAPPGAPQAPSPP-----QGSPQDQHHFLRSSVRPQSKRPRKD-----PPSAVG 103
            +G  GPP P G P    PP     +G+P  +    R    P +K  R +     PP A G
Sbjct: 991  SGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDG-SPGAKGDRGETGPAGPPGAPG 1049

Query: 104  SGNAGGS-GPRGKGAEGGGSSSGNVSGVAPAAPAG--GSRSSSRNLGSSGGEKEEGKK 158
            +  A G  GP GK  +      G      PA P G  G+R  +   G  G + E G++
Sbjct: 1050 APGAPGPVGPAGKSGD-----RGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQ 1102



 Score = 38.9 bits (89), Expect = 0.032
 Identities = 42/152 (27%), Positives = 54/152 (35%), Gaps = 7/152 (4%)

Query: 8   GGSGEDGLKKLGKRAADEESLEG-EGAGGADAAEESSGTKRDEKTP-RAGADGPPAPPGA 65
           G +G  G+K  G R      L+G +G  G    +   G+  +   P + G  G P   G 
Sbjct: 257 GTAGLPGMK--GHRGFS--GLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGR 312

Query: 66  PQAPSPPQGSPQDQHHFLRSSVRPQSKRPRKDPPSAVGS-GNAGGSGPRGKGAEGGGSSS 124
           P AP P      D          P         P AVG+ G AG  GPRG     G    
Sbjct: 313 PGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGE 372

Query: 125 GNVSGVAPAAPAGGSRSSSRNLGSSGGEKEEG 156
               G A AA   G+  +    G+ G     G
Sbjct: 373 PGPPGPAGAAGPAGNPGADGQPGAKGANGAPG 404



 Score = 37.4 bits (85), Expect = 0.092
 Identities = 41/149 (27%), Positives = 50/149 (33%), Gaps = 23/149 (15%)

Query: 24  DEESLEGEGAGGADAAEESSGTK----RDEKTPRAGADGPPAPPGAPQAPS-PPQGSPQD 78
           D+E+   EG  G        G      RD    + G  GPP PPG P  P      +PQ 
Sbjct: 104 DQETTGVEGPKGDTGPRGPRGPAGPPGRDGIPGQPGLPGPPGPPGPPGPPGLGGNFAPQL 163

Query: 79  QHHFLRSS---------VRPQSKRPRKDPPSAVGSGNAGGSGPRGKGAEGGGSSSGNVSG 129
            + +   S         + P   R    PP A   G  G  GP G+  E G S       
Sbjct: 164 SYGYDEKSTGGISVPGPMGPSGPRGLPGPPGA--PGPQGFQGPPGEPGEPGASGP----- 216

Query: 130 VAPAAPAG--GSRSSSRNLGSSGGEKEEG 156
           + P  P G  G        G  G   E G
Sbjct: 217 MGPRGPPGPPGKNGDDGEAGKPGRPGERG 245



 Score = 37.4 bits (85), Expect = 0.092
 Identities = 43/159 (27%), Positives = 59/159 (37%), Gaps = 11/159 (6%)

Query: 8   GGSGEDGLKKLGKRAAD-EESLEGEGA--GGADAAEESSGTKRDEKTPRAGADGPPAPPG 64
           G  GE G +  G R ++  + + GE    G A AA  +     D +    GA+G P   G
Sbjct: 350 GAKGEAGPQ--GPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAG 407

Query: 65  AP-----QAPSPPQGSPQDQHHFLRSSVRPQSKRPRKDPPSAVGSGNAGGSGPRGKGAEG 119
           AP     + PS PQG P        +S  P +   + D  +    G  G  GP G   E 
Sbjct: 408 APGFPGARGPSGPQG-PGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEE 466

Query: 120 GGSSSGNVSGVAPAAPAGGSRSSSRNLGSSGGEKEEGKK 158
           G   +    G        G R    + G  G +   G K
Sbjct: 467 GKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPK 505



 Score = 36.6 bits (83), Expect = 0.16
 Identities = 37/133 (27%), Positives = 45/133 (33%), Gaps = 12/133 (9%)

Query: 38   AAEESSGTKRDEKTP--RAGADGPPAPPG--------APQAPSPPQGSPQDQHHFLRSSV 87
            A +E     R E  P  R G  GPP PPG            P+   G+P  Q    +  V
Sbjct: 901  AGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGV 960

Query: 88   --RPQSKRPRKDPPSAVGSGNAGGSGPRGKGAEGGGSSSGNVSGVAPAAPAGGSRSSSRN 145
               P  +  R  P     SG  G  GP G   E G        G+A      G   +   
Sbjct: 961  VGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGA 1020

Query: 146  LGSSGGEKEEGKK 158
             GS G +   G K
Sbjct: 1021 EGSPGRDGSPGAK 1033



 Score = 36.2 bits (82), Expect = 0.20
 Identities = 42/148 (28%), Positives = 48/148 (32%), Gaps = 30/148 (20%)

Query: 32  GAGGADAAEESSGTKRDEKTPR-AGADGPPAP--PGAPQAPSPPQGSPQDQHHFLRSSVR 88
           GA G   A+ ++G       P   GA GP  P  PG P  P    G P         +  
Sbjct: 389 GADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEP--------GAPG 440

Query: 89  PQSKRPRKDPPSAVG----SGNAGGSGPRG-------------KGAEGGGSSSG--NVSG 129
            +     K  P  VG     G AG  G RG              G  GG  S G     G
Sbjct: 441 SKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADG 500

Query: 130 VAPAAPAGGSRSSSRNLGSSGGEKEEGK 157
           VA      G R S    G  G   E G+
Sbjct: 501 VAGPKGPAGERGSPGPAGPKGSPGEAGR 528



 Score = 35.8 bits (81), Expect = 0.27
 Identities = 36/133 (27%), Positives = 47/133 (35%), Gaps = 27/133 (20%)

Query: 50  KTPRAGADGPPAPPGAPQAPSPPQGSPQDQHHFLRSSVRPQS-----KRPRKDPPSAVGS 104
           K  R G  GPP P GA   P    G P  + H   S +           P+ +P S   +
Sbjct: 237 KPGRPGERGPPGPQGARGLPG-TAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGEN 295

Query: 105 GNAGGSGPRG-------------KGAEGGGSSSGNVSGVAPAAPAG--------GSRSSS 143
           G  G  GPRG              GA G   ++G      P  PAG        G++  +
Sbjct: 296 GAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEA 355

Query: 144 RNLGSSGGEKEEG 156
              G  G E  +G
Sbjct: 356 GPQGPRGSEGPQG 368



 Score = 35.8 bits (81), Expect = 0.27
 Identities = 59/227 (25%), Positives = 79/227 (34%), Gaps = 27/227 (11%)

Query: 443  PPAQILGIQS-GQGTARGQVKCPRS----GAEGKGVGRPPPAADALQSSGESSPESAPGE 497
            PP  I  + + G   ARG    P +    GA G+ VG P P       SG + P   PG 
Sbjct: 849  PPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGR-VGPPGP-------SGNAGPPGPPGP 900

Query: 498  GAALSLSSPDAPDRPPPRHQDTGPCLEKTPAEGRDSPTRE-PGALPCACGQLPDLEDELS 556
                    P     P  R  + GP     PA  + SP  + P   P   G          
Sbjct: 901  AGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGV 960

Query: 557  LLDPLPRYLKSCQDLIVP--EQCRCADTRPGSEQPPLGGAASPEVLAPVSKEAADLAPTG 614
            +  P  R  +    L  P  E  +   +    E+ P G    P +  P  +   + AP G
Sbjct: 961  VGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAP-G 1019

Query: 615  PSPRPGPGLLLDVCTKDLADAPAEELQEKGSPAGPPPSQGQPAARPP 661
                PG         +D +     +  E G PAGPP + G P A  P
Sbjct: 1020 AEGSPG---------RDGSPGAKGDRGETG-PAGPPGAPGAPGAPGP 1056



 Score = 34.7 bits (78), Expect = 0.60
 Identities = 41/155 (26%), Positives = 51/155 (32%), Gaps = 22/155 (14%)

Query: 8   GGSGEDGLKKLGKR-------AADEESLEGEGAGGADAAEESSGTKRDEKTPRA-----G 55
           G +GE G  K G+R       A      +GE              +R E+ P       G
Sbjct: 587 GAAGEPG--KAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQG 644

Query: 56  ADGPPAPPGAPQAPSPPQGSPQDQHHFLRSSVRPQSKRPRKDPPSAVGSGNAGGSGPRGK 115
             GP  PPG    P   QG P D       +  P   R  +  P     G  G  GP G 
Sbjct: 645 LPGPAGPPGEAGKPGE-QGVPGDL-----GAPGPSGARGERGFPGE--RGVQGPPGPAGP 696

Query: 116 GAEGGGSSSGNVSGVAPAAPAGGSRSSSRNLGSSG 150
               G   +    G A A  A GS+ +    G  G
Sbjct: 697 RGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPG 731



 Score = 33.9 bits (76), Expect = 1.0
 Identities = 26/87 (29%), Positives = 29/87 (33%), Gaps = 13/87 (14%)

Query: 8    GGSGEDGLKKLGKRAADEESLEGEGAGGADAAEESSGTKRDE----KTPRAGADGPPAPP 63
            G  GE G       A         GA G D      G         +T  AG  GPP PP
Sbjct: 1124 GSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGDAGPVGPPGPP 1183

Query: 64   GAPQAPSPPQGS---------PQDQHH 81
            G P  P PP            PQ++ H
Sbjct: 1184 GPPGPPGPPSAGFDFSFLPQPPQEKAH 1210



 Score = 33.5 bits (75), Expect = 1.3
 Identities = 35/141 (24%), Positives = 48/141 (34%), Gaps = 25/141 (17%)

Query: 32  GAGGADAAEESSGTKRDEKTPRAGADGPPAP------------PGAPQAPSPP--QGSPQ 77
           G  GA  ++  +G K  E  P  G  GPP P            PG    P PP  +G P 
Sbjct: 434 GEPGAPGSKGDTGAK-GEPGP-VGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPG 491

Query: 78  DQHHFLRSSVRPQSKRPRKDPPSAVGS-GNAGGSGPRGKGAEGGGSSSGNVSGVAPAAPA 136
            +       V          P    G  G+ G +GP+G   E G      + G      +
Sbjct: 492 SRGFPGADGVA--------GPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGS 543

Query: 137 GGSRSSSRNLGSSGGEKEEGK 157
            GS       G  G   ++G+
Sbjct: 544 PGSPGPDGKTGPPGPAGQDGR 564



 Score = 32.0 bits (71), Expect = 3.9
 Identities = 36/109 (33%), Positives = 39/109 (35%), Gaps = 14/109 (12%)

Query: 32  GAGGADAAEESSGTKRDEK-TPRAGADGPPAPPGAPQAPSPPQGSPQDQHHFLRSSVRPQ 90
           G GG  A + S G   DEK T      GP  P G    P PP G+P  Q          Q
Sbjct: 154 GLGGNFAPQLSYGY--DEKSTGGISVPGPMGPSGPRGLPGPP-GAPGPQGF--------Q 202

Query: 91  SKRPRKDPPSAVGS-GNAGGSGPRGK-GAEGGGSSSGNVSGVAPAAPAG 137
                   P A G  G  G  GP GK G +G     G      P  P G
Sbjct: 203 GPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQG 251


>gi|41349484 proline-rich protein BstNI subfamily 1 isoform 2
           preproprotein [Homo sapiens]
          Length = 198

 Score = 47.4 bits (111), Expect = 9e-05
 Identities = 35/102 (34%), Positives = 42/102 (41%), Gaps = 10/102 (9%)

Query: 51  TPRAG--ADGPPAPPGAPQAPSP-----PQGSPQDQHHFLRSSVRPQSKRPRKDPPSAVG 103
           +P+ G    GPP PPG PQ P P     PQG P             +S+ PR  P    G
Sbjct: 40  SPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQG 99

Query: 104 SGNAGGSGPRGKGAEGGGSSSGNVSGVAPAAP--AGGSRSSS 143
               GG  P+G   +GG    G      P  P   GGS+S S
Sbjct: 100 PPPQGGK-PQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQS 140



 Score = 40.8 bits (94), Expect = 0.008
 Identities = 30/93 (32%), Positives = 39/93 (41%), Gaps = 11/93 (11%)

Query: 47  RDEKTPRAGADGPPAPPGAPQAPSPPQGSPQDQHHFLRSSVRPQSKRPRKDPPSAVGSGN 106
           R  ++P     GPP   G PQ P PPQG  + Q         P      + PP+  GS +
Sbjct: 88  RSPRSPPGKPQGPPPQGGKPQGP-PPQGGNKPQ--------GPPPPGKPQGPPAQGGSKS 138

Query: 107 AGGSGPRGKGAEGGGSSSGNVSGVAPAAPAGGS 139
                P GK  +G     GN +   P  PAGG+
Sbjct: 139 QSARSPPGK-PQGPPQQEGN-NPQGPPPPAGGN 169



 Score = 38.5 bits (88), Expect = 0.041
 Identities = 32/108 (29%), Positives = 37/108 (34%), Gaps = 24/108 (22%)

Query: 52  PRAGADGP--PAPPGAPQAPSP----------PQGSPQDQHHFLRSSVRPQSKRPRKDPP 99
           P  G + P  P PPG PQ P P          P G PQ           PQ  +P+  PP
Sbjct: 61  PPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQ--------GPPPQGGKPQGPPP 112

Query: 100 SAVGSGNAGGSGPRGK--GAEGGGSSSGNVSGVAPAAPAGGSRSSSRN 145
              G     G  P GK  G    G S    +   P  P G  +    N
Sbjct: 113 Q--GGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNN 158



 Score = 33.5 bits (75), Expect = 1.3
 Identities = 24/80 (30%), Positives = 28/80 (35%), Gaps = 21/80 (26%)

Query: 584 PGSEQ-PPLGGAASPEVLAPVSKEAADLAPTGPSPRPGPGLLLDVCTKDLADAPAEELQE 642
           PG  Q PP  G   P+   P  K      P GP P+               D        
Sbjct: 54  PGKPQGPPPQGGNKPQGPPPPGK------PQGPPPQ--------------GDKSRSPRSP 93

Query: 643 KGSPAGPPPSQGQPAARPPK 662
            G P GPPP  G+P   PP+
Sbjct: 94  PGKPQGPPPQGGKPQGPPPQ 113



 Score = 30.8 bits (68), Expect = 8.6
 Identities = 21/70 (30%), Positives = 29/70 (41%), Gaps = 11/70 (15%)

Query: 34  GGADAAEESSGTKRDEKTPRAGADGPPAPP----GAPQAP-SPPQGSPQDQHHFLRSSVR 88
           GG+ +    S   + +  P+   + P  PP    G PQ P +PP G PQ           
Sbjct: 134 GGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPR------P 187

Query: 89  PQSKRPRKDP 98
           PQ  RP + P
Sbjct: 188 PQGGRPSRPP 197


>gi|236459851 ubinuclein 2 [Homo sapiens]
          Length = 1347

 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 92/437 (21%), Positives = 163/437 (37%), Gaps = 33/437 (7%)

Query: 769  PGKVVTVSSRSPRCPRNQASLRSSKTFPPSSAPCSSGLRNPPRPLLVPGPSSTGSNDSDG 828
            P K   + +  P+            +FP     CS          LV   S   ++ S  
Sbjct: 675  PAKKKVIPAPKPKVKEVMVKTLPLHSFPTMLKECSPKKDQKTPTSLVASVSGPPTSSSTA 734

Query: 829  GLFAVPTTLPPNSRHGKLFSPSKEAELTFRQHLNSISMQSDFFLPKPRKLRNRHLRKPL- 887
             + A  ++  P ++       S + +L+F  H  S+ + S+        + N +   P+ 
Sbjct: 735  AIAAASSSSAP-AQETICLDDSLDEDLSF--HSPSLDLVSEALAV----INNGNKGPPVG 787

Query: 888  --VVQRTLLPRPSENQSHNVCSFSILSNSSVTGRGSFRPIQSSLTKAALSRPIVPKVLPP 945
              +   T  PRP   +       S L  ++     S +   SS   A  + P+  K   P
Sbjct: 788  SRISMPTTKPRPGLREEKLASIMSKLPLATPKKLDSTQTTHSSSLIAGHTGPVPKK---P 844

Query: 946  QATSHLASAIDLAATSA---GILSGNPLPA-LDTEGLSGISPL-----SSDEVTGAISGQ 996
            Q  +H   +  L A S+     +S  PLPA L  +GL   S +     S   V+ +   Q
Sbjct: 845  QDLAHTGISSGLIAGSSIQNPKVSLEPLPARLLQQGLQRSSQIHTSSSSQTHVSSSSQAQ 904

Query: 997  DSTGTHQDGDTLPTVGGSDPFVSIPSRPEQEPVADSFQGSSVLSLSELPKAPLQNGLSIP 1056
             +  +H  G +      S     +    +   V  ++      ++S+    P+    + P
Sbjct: 905  IAASSHALGTSEAQDASS--LTQVTKVHQHSAVQQNYVSPLQATISKSQTNPVVKLSNNP 962

Query: 1057 LSSSESSSTRLSPPDVSALLDISLPGPPEDA------LSQGEPATHISDSIIEIAISSGQ 1110
              S  SS  + S   +   L +S P P   +      +S+  P+T  S + +  A+ S  
Sbjct: 963  QLSCSSSLIKTSDKPLMYRLPLSTPSPGNGSQGSHPLVSRTVPSTTTSSNYLAKAMVSQI 1022

Query: 1111 YGEGVPLSPAKLNGSDSSKSLPSPSSSPQPHWIASPTHDPQWYPSDSTDSSLSSLFASFI 1170
              +G   SP  +  S    + P P++SP+P     P+  P+  PS S   S+S+   S  
Sbjct: 1023 STQGFK-SPFSMAASPKLAASPKPATSPKPLPSPKPSASPK--PSLSAKPSVSTKLISKS 1079

Query: 1171 SPEKSRKMLPTPIGTNS 1187
            +P     + P+    N+
Sbjct: 1080 NPTPKPTVSPSSSSPNA 1096


>gi|58530876 melanoma antigen family C, 1 [Homo sapiens]
          Length = 1142

 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 180/785 (22%), Positives = 273/785 (34%), Gaps = 160/785 (20%)

Query: 483  LQSSGESSPESAP-GEGAALSL----SSPDAPDRPPPRH--------QDTGPCLEKTPAE 529
            LQSS ES P+S P GE +   L    SSP++ D   P          +D+   L++ P E
Sbjct: 15   LQSSSES-PQSCPEGEDSQSPLQIPQSSPESDDTLYPLQSPQSRSEGEDSSDPLQRPP-E 72

Query: 530  GRDSPTREPGALPCACGQLPDLEDELSLLDPLPRYLKSCQDLIVPEQCRCADTRPGSEQP 589
            G+DS  + P  +P +  +  D +  L      P      +D + P +   +       Q 
Sbjct: 73   GKDS--QSPLQIPQSSPEGDDTQSPLQNSQSSPEG----KDSLSPLEISQSPPEGEDVQS 126

Query: 590  PLGGAASPEVLAPVSKEAADLAPTGPSPRPG-PGLLLDVCTKDLADAPAEELQEKGSPAG 648
            PL   AS    + +         +  SP  G P  +L +     + +    + +    + 
Sbjct: 127  PLQNPASSFFSSALLSIFQSSPESTQSPFEGFPQSVLQIPVSAASSSTLVSIFQSSPEST 186

Query: 649  PPPSQGQPAARPPKEVPASRLAQQLREEGWNLQTSESLTLAEVYLMMGKPSKLQLEYDWL 708
              P +G P +  P ++P SR              S S TL  ++     P + Q  ++  
Sbjct: 187  QSPFEGFPQS--PLQIPVSR--------------SFSSTLLSIF--QSSPERTQSTFEGF 228

Query: 709  GPGRQDPRPGSLPTALHKQRLLSCLLKLISTEVNPKLALEANTISTASVRPAQEEQSMTP 768
                    P  +P +      L  L +  S          A +     V P+        
Sbjct: 229  AQS-----PLQIPVSPSSSSTLLSLFQSFSERTQSTFEGFAQSSLQIPVSPSFSST---- 279

Query: 769  PGKVVTVSSRSPRCPRNQASLRSSKTFP--PSSAPCSSGLRNPPRPLLVPGPSSTGSNDS 826
               +V++   SP   R Q++      FP  P   P SS   +    L    P  T S   
Sbjct: 280  ---LVSLFQSSPE--RTQSTFEG---FPQSPLQIPVSSSSSSTLLSLFQSSPERTHSTFE 331

Query: 827  D--GGLFAVPTTLPPNSRHGKLFSPSKE-AELTFR-------QHLNSISMQS---DFFLP 873
                 L  +P T   +S    +F  S E A+ TF        Q   S S  S     F  
Sbjct: 332  GFPQSLLQIPMTSSFSSTLLSIFQSSPESAQSTFEGFPQSPLQIPGSPSFSSTLLSLFQS 391

Query: 874  KPRKLRNRHL---RKPLVVQRTLLPRPSENQSHNVCSFSILSNSSVTGRGSFR------- 923
             P +  +      + PL +  T         S +    SIL +S  + + +F        
Sbjct: 392  SPERTHSTFEGFPQSPLQIPMT--------SSFSSTLLSILQSSPESAQSAFEGFPQSPL 443

Query: 924  --PIQSSLTKAALSR---------------PIVPKVLPPQATSHLASAIDLAATSA---- 962
              P+ SS +   LS                P  P  +P  ++S  ++ + L  +S     
Sbjct: 444  QIPVSSSFSYTLLSLFQSSPERTHSTFEGFPQSPLQIPVSSSSSSSTLLSLFQSSPECTQ 503

Query: 963  GILSGNP-----LPALDTEGLSGISPL----SSDEVTGAIS----------GQDSTGTHQ 1003
                G P     +P    EG +  SPL    S  E   ++S          G+DS   H 
Sbjct: 504  STFEGFPQSPLQIPQSPPEGENTHSPLQIVPSLPEWEDSLSPHYFPQSPPQGEDSLSPHY 563

Query: 1004 DGDTLPTVGGSDPFVSIPSRPEQEPVADSF-------QGSSVLSLSELPKAPLQ-----N 1051
               + P    S      P  P+ E             QG   +S    P++PLQ     +
Sbjct: 564  FPQSPPQGEDSLSPHYFPQSPQGEDSLSPHYFPQSPPQGEDSMSPLYFPQSPLQGEEFQS 623

Query: 1052 GLSIPLSSSESSS----------TRLSPPDVSALLDISLP-GPPEDALSQGEPATHISDS 1100
             L  P+S   SS+          +  SPP+      +  P  PPE   SQ    +  S  
Sbjct: 624  SLQSPVSICSSSTPSSLPQSFPESSQSPPEGPVQSPLHSPQSPPEGMHSQSPLQSPESAP 683

Query: 1101 IIEIAISSGQYGEGVPLSPAKLNGSDSSKSLPSPSSSPQPHWIASPTHDPQWYP-SDSTD 1159
              E ++S  Q    +P SP  L G DS  SL  P S P+     SP H PQ+ P  +   
Sbjct: 684  EGEDSLSPLQ----IPQSP--LEGEDSLSSLHFPQSPPEWEDSLSPLHFPQFPPQGEDFQ 737

Query: 1160 SSLSS 1164
            SSL S
Sbjct: 738  SSLQS 742



 Score = 44.3 bits (103), Expect = 8e-04
 Identities = 63/226 (27%), Positives = 95/226 (42%), Gaps = 38/226 (16%)

Query: 1017 FVSIPSRPEQEPVADSFQGSSVLSLSE------------LPKAPLQNGLSIPLSSSESSS 1064
            F   P  P Q PV+ SF   ++LSL +             P++PLQ    IP+SSS SSS
Sbjct: 435  FEGFPQSPLQIPVSSSFS-YTLLSLFQSSPERTHSTFEGFPQSPLQ----IPVSSSSSSS 489

Query: 1065 TRL----SPPDVSALLDISLPGPPEDALSQGEPATHISDSIIEIAISSGQYGEGV----- 1115
            T L    S P+ +       P  P   + Q  P    + S ++I  S  ++ + +     
Sbjct: 490  TLLSLFQSSPECTQSTFEGFPQSPLQ-IPQSPPEGENTHSPLQIVPSLPEWEDSLSPHYF 548

Query: 1116 PLSPAKLNGSDSSKSLPSPSSSPQPHWIASPTHDPQWYPSDSTDSSLSSLFASFISPEKS 1175
            P SP +  G DS      P S PQ     SP + PQ   S   + SLS  +     P+  
Sbjct: 549  PQSPPQ--GEDSLSPHYFPQSPPQGEDSLSPHYFPQ---SPQGEDSLSPHYFPQSPPQGE 603

Query: 1176 RKMLP-----TPI-GTNSGTSLLGPSLLDGNSRDSFVSRSLADVAE 1215
              M P     +P+ G    +SL  P  +  +S  S + +S  + ++
Sbjct: 604  DSMSPLYFPQSPLQGEEFQSSLQSPVSICSSSTPSSLPQSFPESSQ 649



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 77/281 (27%), Positives = 115/281 (40%), Gaps = 40/281 (14%)

Query: 971  PALDTEGLSGISPLSSDEVTGAISGQDSTGTHQDGDTLPTVGGSDPFVSIPSRPEQEPVA 1030
            P    EG+   SPL S E   A  G+DS    Q   +   + G D   S+   P+  P  
Sbjct: 663  PQSPPEGMHSQSPLQSPE--SAPEGEDSLSPLQIPQS--PLEGEDSLSSLHF-PQSPP-- 715

Query: 1031 DSFQGSSVLSLSELPKAP-----LQNGLSIPLSSSESSSTRLSPPDVSALLDISLPGPPE 1085
               +    LS    P+ P      Q+ L  P+S   SSST LS P        S P  P 
Sbjct: 716  ---EWEDSLSPLHFPQFPPQGEDFQSSLQSPVSIC-SSSTSLSLPQSFPESPQSPPEGPA 771

Query: 1086 DALSQGEPATHISDSIIEIAISSGQYGEGVPLSPAKLNGSDSSKSLPSPSSSPQPHWIAS 1145
             +  Q   ++  S ++  +  SS +  +  P  PA+        S PS +SS      +S
Sbjct: 772  QSPLQRPVSSFFSYTLASLLQSSHESPQSPPEGPAQSPLQSPVSSFPSSTSSSLSQ--SS 829

Query: 1146 PTHDPQWYPSDSTDSSLSSLFASFISPEKSRKMLPTPIGTNSGTSLLGPSLLDGNSR-DS 1204
            P      +PS ST SSLS       SPE     L +P+ + S ++ L P   + +S  D 
Sbjct: 830  PVSS---FPS-STSSSLSK-----SSPESP---LQSPVISFSSSTSLSPFSEESSSPVDE 877

Query: 1205 FVSR--------SLADVAEVVDSQ-LVCMMNENSIDYISRF 1236
            + S         SL D   +++S+ L     +  +D ++RF
Sbjct: 878  YTSSSDTLLESDSLTDSESLIESEPLFTYTLDEKVDELARF 918



 Score = 35.4 bits (80), Expect = 0.35
 Identities = 91/385 (23%), Positives = 145/385 (37%), Gaps = 54/385 (14%)

Query: 812  PLLVPGPSSTGSNDSDGGLFAVPTTLPPNSRHGKLFSPSKEAELTFRQHLNSISMQSDFF 871
            P L+   S +  +  +G     P  +P +S       P  +  L   Q   S S   D  
Sbjct: 12   PSLLQSSSESPQSCPEGEDSQSPLQIPQSS-------PESDDTLYPLQSPQSRSEGEDSS 64

Query: 872  LPKPRKLRNRHLRKPLVVQRTLLPRPSENQS--HNVCSFSILSNSSVTGRGSFRPIQSSL 929
             P  R    +  + PL + ++  P   + QS   N       S SS  G+ S  P++  +
Sbjct: 65   DPLQRPPEGKDSQSPLQIPQSS-PEGDDTQSPLQN-------SQSSPEGKDSLSPLE--I 114

Query: 930  TKAALSRPIVPKVLPPQATSHLASAIDLAATSAGILSGNPLPALDTEGLS-GISPLSSDE 988
            +++      V   L   A+S  +SA+     S+   + +P        L   +S  SS  
Sbjct: 115  SQSPPEGEDVQSPLQNPASSFFSSALLSIFQSSPESTQSPFEGFPQSVLQIPVSAASSST 174

Query: 989  VTGAI-SGQDSTGTHQDGDTLPTVGGSDPFVSIPSRPEQEPVADSFQGSSVLSLSELPKA 1047
            +     S  +ST                PF   P  P Q PV+ SF  + +      P+ 
Sbjct: 175  LVSIFQSSPEST--------------QSPFEGFPQSPLQIPVSRSFSSTLLSIFQSSPER 220

Query: 1048 P-------LQNGLSIPLSSSESSSTRLSPPDVSALLDISLPGPPEDALSQGEPATHISDS 1100
                     Q+ L IP+S S SS+        S     +  G  + +L Q   +   S +
Sbjct: 221  TQSTFEGFAQSPLQIPVSPSSSSTLLSLFQSFSERTQSTFEGFAQSSL-QIPVSPSFSST 279

Query: 1101 IIEIAISSGQYG----EGVPLSPAKLNGSDSSKS--LPSPSSSPQ---PHWIASPTHDPQ 1151
            ++ +  SS +      EG P SP ++  S SS S  L    SSP+     +   P    Q
Sbjct: 280  LVSLFQSSPERTQSTFEGFPQSPLQIPVSSSSSSTLLSLFQSSPERTHSTFEGFPQSLLQ 339

Query: 1152 WYPSDSTDSSLSSLFASFISPEKSR 1176
               + S  S+L S+F S  SPE ++
Sbjct: 340  IPMTSSFSSTLLSIFQS--SPESAQ 362


>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
          Length = 416

 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 36/109 (33%), Positives = 48/109 (44%), Gaps = 14/109 (12%)

Query: 34  GGADAAEESSGTKRDEKTPRAGAD---GPPAPPGAPQAPSPPQGSPQDQHHFLRSSVRPQ 90
           GG+ +    S   + +  P  G +   GPP PPG PQ P PPQG  + Q         P 
Sbjct: 290 GGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGP-PPQGGNKPQG-------PPP 341

Query: 91  SKRPRKDPPSAVGSGNAGGSGPRGKGAEGGGSSSGNVSGVAPAAPAGGS 139
             +P+  PP   GS +     P GK  +G     GN +   P  PAGG+
Sbjct: 342 PGKPQGPPPQG-GSKSRSARSPPGK-PQGPPQQEGN-NPQGPPPPAGGN 387



 Score = 42.4 bits (98), Expect = 0.003
 Identities = 40/141 (28%), Positives = 51/141 (36%), Gaps = 22/141 (15%)

Query: 34  GGADAAEESSGTKRDEKTPRAG--ADGPPAPPGAPQAPSP--------------PQGSPQ 77
           G    +  S   K     P+ G    GPP PPG PQ P P              PQG P 
Sbjct: 105 GDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPP 164

Query: 78  DQHHFLRSSVRPQSKRPRKDPPSAVGSGNAGGSGPRGK----GAEGGGSSSGNVSGVAPA 133
              +  RSS  P  K P+  PP   G+   G   P GK      +GG    G      P 
Sbjct: 165 QGDNKSRSSRSPPGK-PQGPPPQG-GNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQ 222

Query: 134 APAGGSRSSSRNLGSSGGEKE 154
            P     + S++  S  G+ +
Sbjct: 223 GPPPQGDNKSQSARSPPGKPQ 243



 Score = 41.6 bits (96), Expect = 0.005
 Identities = 39/136 (28%), Positives = 46/136 (33%), Gaps = 28/136 (20%)

Query: 33  AGGADAAEESSGTKRDEKTPRAGADGPPAPPGAPQAPSPPQGSPQDQHHFLRSSVRPQSK 92
           AG    A    G K           GPP+PPG PQ P PPQG  Q Q         P   
Sbjct: 33  AGNPQGAPPQGGNK---------PQGPPSPPGKPQGP-PPQGGNQPQ------GPPPPPG 76

Query: 93  RPRKDPPSAVGS-------GNAGGSGPRGKGAEGGGSSSGNVSGVAPAA---PAGGSRSS 142
           +P+  PP            G   G  P+G  +    S  G   G  P     P G     
Sbjct: 77  KPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPP 136

Query: 143 SRNLG--SSGGEKEEG 156
            +  G    GG K +G
Sbjct: 137 GKPQGPPPQGGNKPQG 152



 Score = 41.6 bits (96), Expect = 0.005
 Identities = 35/115 (30%), Positives = 44/115 (38%), Gaps = 20/115 (17%)

Query: 58  GPPAPPGAPQAPSP--------------PQGSPQDQHHFLRSSVRPQSKRPRKDPPSAVG 103
           GPP PPG PQ P P              PQG P    +  +S+  P  K P+  PP   G
Sbjct: 193 GPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGK-PQGPPPQG-G 250

Query: 104 SGNAGGSGPRGK----GAEGGGSSSGNVSGVAPAAPAGGSRSSSRNLGSSGGEKE 154
           +   G   P GK      +GG    G      P  P     S SR+  S  G+ +
Sbjct: 251 NQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQ 305



 Score = 41.2 bits (95), Expect = 0.006
 Identities = 41/142 (28%), Positives = 50/142 (35%), Gaps = 19/142 (13%)

Query: 31  EGAGGADAAEESSGTKRDEKTPRAG--ADGPPAPPGAPQAPSP----------PQGSPQD 78
           +G   + +A    G K     P+ G    GPP PPG PQ P P          P G PQ 
Sbjct: 227 QGDNKSQSARSPPG-KPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQG 285

Query: 79  QHHFLRSSVRPQSKRPRK--DPPSAVGSGNAGGSGPRGK----GAEGGGSSSGNVSGVAP 132
                 S  R     P K   PP   G+   G   P GK      +GG    G      P
Sbjct: 286 PPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKP 345

Query: 133 AAPAGGSRSSSRNLGSSGGEKE 154
             P     S SR+  S  G+ +
Sbjct: 346 QGPPPQGGSKSRSARSPPGKPQ 367



 Score = 39.3 bits (90), Expect = 0.024
 Identities = 54/197 (27%), Positives = 65/197 (32%), Gaps = 26/197 (13%)

Query: 470 GKGVGRPPPAADALQSSGES---SPESAPGEGAALSLSSPDAPDRPPPRHQDTGPCLEKT 526
           GK  G PPP  D    S  S    P+  P +G     + P  P  PPP  +  GP     
Sbjct: 157 GKPQG-PPPQGDNKSRSSRSPPGKPQGPPPQGG----NQPQGP--PPPPGKPQGP----- 204

Query: 527 PAEGRDSPTREPGALPCACGQLPDLEDELSLLDPLPRYLKSCQDLIVPEQCRCADTRPGS 586
           P +G + P   P   P      P   D  S     P             Q +     PG 
Sbjct: 205 PPQGGNKPQGPPP--PGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGK 262

Query: 587 EQ-PPLGGAASPEVLAPVSKEAADLAPTGPSPRPGPGLLLDVCTKDLADAPAEELQEKGS 645
            Q PP  G   P+   P  K      P GP P+ G               P    Q    
Sbjct: 263 PQGPPPQGGNKPQGPPPPGK------PQGPPPQGGSKSRSSRSPPGKPQGPPP--QGGNQ 314

Query: 646 PAGPPPSQGQPAARPPK 662
           P GPPP  G+P   PP+
Sbjct: 315 PQGPPPPPGKPQGPPPQ 331



 Score = 38.9 bits (89), Expect = 0.032
 Identities = 48/207 (23%), Positives = 66/207 (31%), Gaps = 48/207 (23%)

Query: 464 PRSGAEGKGVGRPPPAADALQSSGESSPESAP---GEGAALSLSSPDAPDRPPPRHQDTG 520
           P+ G + +G   PP         G + P+  P   G+         + P  PPP  +  G
Sbjct: 41  PQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQG 100

Query: 521 PCLEKTPAEGRDSPTREPGALPCACGQLPDLEDELSLLDPLPRYLKSCQDLIVPEQCRCA 580
           P  +   +    SP  +P   P   G  P          P P                  
Sbjct: 101 PPPQGDKSRSPRSPPGKPQGPPPQGGNQPQ--------GPPPP----------------- 135

Query: 581 DTRPGSEQ-PPLGGAASPEVLAPVSKEAADLAPTGPSPRPGPGLLLDVCTKDLADAPAEE 639
              PG  Q PP  G   P+   P  K      P GP P+       D  ++     P + 
Sbjct: 136 ---PGKPQGPPPQGGNKPQGPPPPGK------PQGPPPQG------DNKSRSSRSPPGKP 180

Query: 640 L----QEKGSPAGPPPSQGQPAARPPK 662
                Q    P GPPP  G+P   PP+
Sbjct: 181 QGPPPQGGNQPQGPPPPPGKPQGPPPQ 207



 Score = 38.1 bits (87), Expect = 0.054
 Identities = 58/229 (25%), Positives = 73/229 (31%), Gaps = 28/229 (12%)

Query: 443 PPAQILGIQSGQGTARGQVKCPRSGAEGKGVGRPPPA---ADALQSSGESSPESAPGEGA 499
           PP Q      G     G+ + P      K  G PPP        Q     SP S PG+  
Sbjct: 60  PPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQ 119

Query: 500 ALSLSSPDAPDRPPPRH-QDTGPCLEKTPAEGRDSPTREPGALPCACGQLPDLEDELSLL 558
                  + P  PPP   +  GP     P +G + P   P   P      P   D  S  
Sbjct: 120 GPPPQGGNQPQGPPPPPGKPQGP-----PPQGGNKPQGPPP--PGKPQGPPPQGDNKSRS 172

Query: 559 DPLPRYLKSCQDLIVPEQCRCADTRPGSEQ-PPLGGAASPEVLAPVSKEAADLAPTGPSP 617
              P             Q +     PG  Q PP  G   P+   P  K      P GP P
Sbjct: 173 SRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGK------PQGPPP 226

Query: 618 RPGPGLLLDVCTKDLADAPAEEL----QEKGSPAGPPPSQGQPAARPPK 662
           +       D  ++     P +      Q    P GPPP  G+P   PP+
Sbjct: 227 QG------DNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQ 269



 Score = 37.7 bits (86), Expect = 0.070
 Identities = 47/205 (22%), Positives = 63/205 (30%), Gaps = 56/205 (27%)

Query: 464 PRSGAEGKGVGRPPPAADALQSSGESSPESAPGEGAALSLSSPDAPDRPPPRHQDTGPCL 523
           P+ G + +G   PP         G + P+  P          P  P  PPP+  +     
Sbjct: 185 PQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPP---------PPGKPQGPPPQGDNKSQSA 235

Query: 524 EKTPAEGRDSPTR---EPGALPCACG--QLPDLEDELSLLDPLPRYLKSCQDLIVPEQCR 578
              P + +  P +   +P   P   G  Q P  +       P P                
Sbjct: 236 RSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPP---------------- 279

Query: 579 CADTRPGSEQ--PPLGGAASPEVLAPVSKEAADLAPTGPSPRPGPGLLLDVCTKDLADAP 636
                PG  Q  PP GG+ S    +P  K      P GP P+ G             + P
Sbjct: 280 -----PGKPQGPPPQGGSKSRSSRSPPGK------PQGPPPQGG-------------NQP 315

Query: 637 AEELQEKGSPAGPPPSQGQPAARPP 661
                  G P GPPP  G     PP
Sbjct: 316 QGPPPPPGKPQGPPPQGGNKPQGPP 340



 Score = 37.0 bits (84), Expect = 0.12
 Identities = 32/124 (25%), Positives = 44/124 (35%), Gaps = 20/124 (16%)

Query: 41  ESSGTKRDEKTPRAGADGPPAPPG-APQAPSPPQGSPQDQHHFLRSSVRPQSK----RPR 95
           +     R  ++P     GPP   G  PQ P PP G PQ      +   +PQ      +P+
Sbjct: 165 QGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPP--QGGNKPQGPPPPGKPQ 222

Query: 96  KDPPSAVGSGNAGGS---GPRGKGAEGGGSSSGNVSGVAPAAPAGGSRSSSRNLGSSGGE 152
             PP       +  S    P+G   +GG    G      P  P G  +         GG 
Sbjct: 223 GPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQG------PPPPPGKPQGPP----PQGGN 272

Query: 153 KEEG 156
           K +G
Sbjct: 273 KPQG 276



 Score = 36.2 bits (82), Expect = 0.20
 Identities = 50/198 (25%), Positives = 64/198 (32%), Gaps = 28/198 (14%)

Query: 470 GKGVGRPPPAADALQS--SGESSPESAPGEGAALSLSSPDAPDRPPPRHQDTGPCLEKTP 527
           GK  G PP   +  QS  S    P+  P +G       P  P +P       G   +  P
Sbjct: 219 GKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPP 278

Query: 528 AEGRDSPTREPGALPCACGQLPDLEDELSLLDPLPRYLKSCQDLIVPEQCRCADTRPGSE 587
             G+       G       + P  + +     P P+     Q    P         PG  
Sbjct: 279 PPGKPQGPPPQGGSKSRSSRSPPGKPQ----GPPPQGGNQPQGPPPP---------PGKP 325

Query: 588 Q-PPLGGAASPEVLAPVSKEAADLAPTGPSPRPGPGLLLDVCTKDLADAPAEELQEKGSP 646
           Q PP  G   P+   P  K      P GP P+ G               P +  QE  +P
Sbjct: 326 QGPPPQGGNKPQGPPPPGK------PQGPPPQGGSKSRSARSPPGKPQGPPQ--QEGNNP 377

Query: 647 AGPPPSQG----QPAARP 660
            GPPP  G    QP A P
Sbjct: 378 QGPPPPAGGNPQQPQAPP 395



 Score = 32.0 bits (71), Expect = 3.9
 Identities = 32/119 (26%), Positives = 43/119 (36%), Gaps = 22/119 (18%)

Query: 47  RDEKTPRAGADGPPAPPGAPQ--APSPPQGSPQDQHHFLRSSVRPQSK----RPRKDPPS 100
           R  ++P     GPP P G  Q   P PP G PQ      +   +PQ      +P+  PP 
Sbjct: 109 RSPRSPPGKPQGPP-PQGGNQPQGPPPPPGKPQGPPP--QGGNKPQGPPPPGKPQGPPPQ 165

Query: 101 AVGSGNAGGS---GPRGKGAEGGGSSSGNVSGVAPAAPAGGSRSSSRNLGSSGGEKEEG 156
                 +  S    P+G   +GG    G      P  P G  +         GG K +G
Sbjct: 166 GDNKSRSSRSPPGKPQGPPPQGGNQPQG------PPPPPGKPQGPP----PQGGNKPQG 214



 Score = 30.8 bits (68), Expect = 8.6
 Identities = 30/107 (28%), Positives = 34/107 (31%), Gaps = 40/107 (37%)

Query: 52  PRAGADGP--PAPPGAPQAPSP---------------PQGSPQDQHHFLRSSVRPQSKRP 94
           P  G + P  P PPG PQ P P               PQG PQ            +   P
Sbjct: 329 PPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQ-----------EGNNP 377

Query: 95  RKDPPSAVGSGNAGGSGPRGKGAEGGGSSSGNVSGVAPAAPAGGSRS 141
           +  PP A       G  P+   A   G   G      P  P GG  S
Sbjct: 378 QGPPPPA-------GGNPQQPQAPPAGQPQG-----PPRPPQGGRPS 412



 Score = 30.8 bits (68), Expect = 8.6
 Identities = 21/70 (30%), Positives = 29/70 (41%), Gaps = 11/70 (15%)

Query: 34  GGADAAEESSGTKRDEKTPRAGADGPPAPP----GAPQAP-SPPQGSPQDQHHFLRSSVR 88
           GG+ +    S   + +  P+   + P  PP    G PQ P +PP G PQ           
Sbjct: 352 GGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPR------P 405

Query: 89  PQSKRPRKDP 98
           PQ  RP + P
Sbjct: 406 PQGGRPSRPP 415


>gi|4507869 vasodilator-stimulated phosphoprotein [Homo sapiens]
          Length = 380

 Score = 46.6 bits (109), Expect = 2e-04
 Identities = 46/169 (27%), Positives = 57/169 (33%), Gaps = 41/169 (24%)

Query: 9   GSGEDGLKKLGKRAADEESLEGEG-----------AGGADAAEESSGTKRDEKTP----- 52
           GS ED  +     A+  E+LEG G                + EE    KR +  P     
Sbjct: 94  GSKEDAAQFAAGMASALEALEGGGPPPPPALPTWSVPNGPSPEEVEQQKRQQPGPSEHIE 153

Query: 53  ----RAG------ADGPPAPPGAPQAPSPPQGSPQDQHHFLRSSVRPQSKRPRKDPPSAV 102
                AG      A GPP PPG P  P PP                P    P   P +A 
Sbjct: 154 RRVSNAGGPPAPPAGGPPPPPGPPPPPGPPP---------------PPGLPPSGVPAAAH 198

Query: 103 GSGNAGGSGPRGKGAEGGGSSSGNVSGVAPAAPAGGSRSSSRNLGSSGG 151
           G+G      P    A+G G       G+A A      R  S+   +SGG
Sbjct: 199 GAGGGPPPAPPLPAAQGPGGGGAGAPGLAAAIAGAKLRKVSKQEEASGG 247



 Score = 34.7 bits (78), Expect = 0.60
 Identities = 27/87 (31%), Positives = 32/87 (36%), Gaps = 17/87 (19%)

Query: 592 GGAASPEVLAPVSKEAADLAPTGPSP---------RPGPGLLLDVCTKDLADAPAEELQE 642
           GG   P  L   S       P GPSP         +PGP   ++    +    PA     
Sbjct: 116 GGPPPPPALPTWS------VPNGPSPEEVEQQKRQQPGPSEHIERRVSNAGGPPAPPAGG 169

Query: 643 KGSPAGPPPSQG--QPAARPPKEVPAS 667
              P GPPP  G   P   PP  VPA+
Sbjct: 170 PPPPPGPPPPPGPPPPPGLPPSGVPAA 196


>gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein
           [Homo sapiens]
          Length = 1650

 Score = 46.6 bits (109), Expect = 2e-04
 Identities = 44/165 (26%), Positives = 58/165 (35%), Gaps = 18/165 (10%)

Query: 8   GGSGEDGLKKLGKRAADEESLEGEGAGGADAAEESSGTKRDEKTPRAGADGPPAPPG--- 64
           G SGE G + L  ++         G  G      ++G    + T  +G DGP  PPG   
Sbjct: 734 GASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGT--SGGDGPHGPPGERG 791

Query: 65  --APQA----------PSPPQGSPQDQHHFLRSSVRPQSKRPRKDPPSAVG-SGNAGGSG 111
              PQ           P PP       H   R  V  Q K     PP  VG  G AG +G
Sbjct: 792 LPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETG 851

Query: 112 PRGKGAEGGGSSSGNVSGVAPAAPAGGSRSSSRNLGSSGGEKEEG 156
           P G+    G        G+   A   G++      G+ G +   G
Sbjct: 852 PMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAG 896



 Score = 41.6 bits (96), Expect = 0.005
 Identities = 37/132 (28%), Positives = 43/132 (32%), Gaps = 6/132 (4%)

Query: 31   EGAGGADAAEESSGTKRDEKTPRAGADGPPAPPGAPQAPSPPQGSPQDQHHFLRSSVRPQ 90
            +G  GA   +   G K DE T   G +GPP P G    P P     +           P 
Sbjct: 1039 DGEPGARGPQGHFGAKGDEGT--RGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPP 1096

Query: 91   SKRPRKDPPSAVGS----GNAGGSGPRGKGAEGGGSSSGNVSGVAPAAPAGGSRSSSRNL 146
              R    P  A G     G  G  GP G+  E G S S  + G        G R      
Sbjct: 1097 GPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGES 1156

Query: 147  GSSGGEKEEGKK 158
            G  G     G K
Sbjct: 1157 GQPGEPGPPGPK 1168



 Score = 41.6 bits (96), Expect = 0.005
 Identities = 52/172 (30%), Positives = 64/172 (37%), Gaps = 36/172 (20%)

Query: 6    GDGGS----GEDGLK-KLGKRAADEESLEGEGAGGADAAEESSGTKRDEKTPRAGADGPP 60
            G+ GS    GE G+K   G+R    ES    G  G        G   D+     G  G P
Sbjct: 1130 GESGSPGIQGEPGVKGPRGERGEKGES----GQPGEPGPPGPKGPTGDD-----GPKGNP 1180

Query: 61   APPGAPQAPSPP-QGSPQDQHHFLRSSV------RPQSKRPRKD--PPSAVGS-GNAGGS 110
             P G P  P PP +G P+ Q              +P S  P  +  PP  +G  G AG  
Sbjct: 1181 GPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSP 1240

Query: 111  GPRG-------KGAEGGGSSSGNVSGVAPAAPAG-----GSRSSSRNLGSSG 150
            G  G       KG  G   + G    V PA PAG     G R    ++G  G
Sbjct: 1241 GSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQG 1292



 Score = 40.4 bits (93), Expect = 0.011
 Identities = 45/176 (25%), Positives = 60/176 (34%), Gaps = 28/176 (15%)

Query: 8    GGSGEDGLKKLGKRAADEESLEGEGAG-GADAAEESSGTKRDEKTP----RAGADGPPAP 62
            G  G+DG   L +    E  L G   G G    E  SG      +P     AG+ GP  P
Sbjct: 887  GAPGKDGPAGL-RGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGP 945

Query: 63   PGAPQAPSPPQGSPQDQHHFLRSSVRPQSKRPRKDPPSAVG----SGNAGGSGPRG---- 114
            PG P    PP  + +      +  + P  +   + P    G     G AG  G +G    
Sbjct: 946  PGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGD 1005

Query: 115  ---KGAEGGGSSSGNVSGVAPAAPAG-----------GSRSSSRNLGSSGGEKEEG 156
               KG +G     G      P  P G           G+R    + G+ G E   G
Sbjct: 1006 PGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRG 1061



 Score = 37.0 bits (84), Expect = 0.12
 Identities = 37/130 (28%), Positives = 46/130 (35%), Gaps = 18/130 (13%)

Query: 31   EGAGGADAAEESSGTKRDEKTPRAGADGPPAPPGAPQAPSPPQGSPQDQHHFLRSSVRPQ 90
            +G  G        G K +   P  G  GPP P G P     P+G+P            P 
Sbjct: 1138 QGEPGVKGPRGERGEKGESGQP--GEPGPPGPKG-PTGDDGPKGNPG-----------PV 1183

Query: 91   SKRPRKDPPSAVGS-GNAGGSGPRGKGAEGGGSSSGNVSGV-APAAPAG--GSRSSSRNL 146
                   PP   G  G  G  G RG+  E G   S   +G   P  P G  G   S  + 
Sbjct: 1184 GFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSE 1243

Query: 147  GSSGGEKEEG 156
            G  GG+  +G
Sbjct: 1244 GRQGGKGAKG 1253



 Score = 36.6 bits (83), Expect = 0.16
 Identities = 39/169 (23%), Positives = 52/169 (30%), Gaps = 14/169 (8%)

Query: 6    GDGGSGEDGLKKLGKRAADEESLEGEGAGGADAAEESSGTKRDEKTP----RAGADGPPA 61
            G G  G+ G      +          G  G D      G+   +  P    +AG  GP  
Sbjct: 1248 GKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVG 1307

Query: 62   PPGAPQAPSPPQGSPQDQHHFLRSSVRPQSKRPRKDP---PSAVGS-------GNAGGSG 111
            PPG P          +  H  L   + P  ++  K     P   GS       G  G SG
Sbjct: 1308 PPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASG 1367

Query: 112  PRGKGAEGGGSSSGNVSGVAPAAPAGGSRSSSRNLGSSGGEKEEGKKVR 160
            P G G   G        G   A   GG +      G  G     G+ ++
Sbjct: 1368 PIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQ 1416



 Score = 36.2 bits (82), Expect = 0.20
 Identities = 38/138 (27%), Positives = 52/138 (37%), Gaps = 14/138 (10%)

Query: 32  GAGGAD-----AAEESSGTKRDEKTPRAGADGPPAPPGAPQAPSP--PQGSPQDQHHFLR 84
           G+GG D     AA+E+      ++  R    GPP P G    P P    GSP  +     
Sbjct: 371 GSGGGDKGPVVAAQEAQAQAILQQA-RLALRGPPGPMGYTGRPGPLGQPGSPGLKGE--S 427

Query: 85  SSVRPQSKRPRK---DPPSAVG-SGNAGGSGPRGKGAEGGGSSSGNVSGVAPAAPAGGSR 140
             + PQ  R  +    PP   G  G AG  G RG   + G        G+       G R
Sbjct: 428 GDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHR 487

Query: 141 SSSRNLGSSGGEKEEGKK 158
             +   G  G   E+G++
Sbjct: 488 GDTGAQGLPGPPGEDGER 505



 Score = 35.4 bits (80), Expect = 0.35
 Identities = 48/161 (29%), Positives = 58/161 (36%), Gaps = 25/161 (15%)

Query: 8   GGSGEDGLKKLGKRAADEESLEGE-GAGGADAAEESSGTKRD--EKTPRA--GADGPPA- 61
           G  G DGL  L      E+   G+ GA G        G + D  E  PR   G  GP   
Sbjct: 470 GDRGFDGLPGL----PGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGL 525

Query: 62  --PPGAPQAPSPPQGSPQDQHHFLRSSVRPQSKRPRKDPPSAVGS-GNAGGSGPRG---- 114
             P G P  P PP     D     + S+ PQ +     PP   G+ G  G  GP+G    
Sbjct: 526 LGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGE---PGPPGQQGTPGTQGLPGPQGAIGP 582

Query: 115 ---KGAEGGGSSSGNVSGVAPAAPAG--GSRSSSRNLGSSG 150
              KG +G     G      P    G  G   +  N G SG
Sbjct: 583 HGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSG 623



 Score = 35.4 bits (80), Expect = 0.35
 Identities = 41/150 (27%), Positives = 51/150 (34%), Gaps = 26/150 (17%)

Query: 31  EGAGGADAAEESSGTKRDEKTPRAGADGPPAPPGA--PQAPSPPQGSPQDQHHFLRSSVR 88
           +G  G+   +   G    + TP  G  G P P GA  P     PQG P      +  S  
Sbjct: 547 QGPKGSLGPQGEPGPPGQQGTP--GTQGLPGPQGAIGPHGEKGPQGKPGLPG--MPGSDG 602

Query: 89  PQSKRPRKDPPSAVGSGNAGGSGPRG----------KGAEG--------GGSSSGNVSGV 130
           P     ++ PP     GN G SGP+G          KG +G        G        G 
Sbjct: 603 PPGHPGKEGPPGT--KGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGF 660

Query: 131 APAAPAGGSRSSSRNLGSSGGEKEEGKKVR 160
                  G R      GS G +  EG K R
Sbjct: 661 KGDIGVKGDRGEVGVPGSRGEDGPEGPKGR 690



 Score = 34.3 bits (77), Expect = 0.78
 Identities = 33/113 (29%), Positives = 38/113 (33%), Gaps = 13/113 (11%)

Query: 55   GADGPPAPPGAPQAPSPP--------QGSPQDQHHFLRSSVR-PQSKRPRKDPPSAVGS- 104
            GADGP  PPG      PP         GSP  Q       V+ P+ +R  K      G  
Sbjct: 1106 GADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGE---PGVKGPRGERGEKGESGQPGEP 1162

Query: 105  GNAGGSGPRGKGAEGGGSSSGNVSGVAPAAPAGGSRSSSRNLGSSGGEKEEGK 157
            G  G  GP G     G        G       GG R      G  G + E G+
Sbjct: 1163 GPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQ 1215



 Score = 33.9 bits (76), Expect = 1.0
 Identities = 32/115 (27%), Positives = 37/115 (32%), Gaps = 10/115 (8%)

Query: 54  AGADGPPAPPGAPQAPSPP--QGSPQDQHHFLRSSVRPQSKRPRKDPPSAVGS------- 104
           AG  GP    G P  P PP  QG P                 P KD P+ +         
Sbjct: 847 AGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGL 906

Query: 105 -GNAGGSGPRGKGAEGGGSSSGNVSGVAPAAPAGGSRSSSRNLGSSGGEKEEGKK 158
            G AGG G +G     G        G   AA +GG        G  G     G+K
Sbjct: 907 PGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEK 961



 Score = 32.3 bits (72), Expect = 3.0
 Identities = 58/217 (26%), Positives = 72/217 (33%), Gaps = 27/217 (12%)

Query: 452 SGQGTARGQVKCPRSGAEGKGVGRPPPAADALQSSGESSPESAPGEGAALSLSSPDAPDR 511
           SG+  ARG      SG  G    R P         G+  P  A G+  A   S  D P  
Sbjct: 736 SGEKGARGL-----SGKSGPRGERGPTGP-----RGQRGPRGATGKSGAKGTSGGDGPHG 785

Query: 512 PPPRHQDTGPCLEKTPAEGRDSPTREPG--ALPCACGQLPDLEDELSLLDPLPRYLKSCQ 569
           PP      GP        G   P   PG   LP   GQ  ++  +     P P       
Sbjct: 786 PPGERGLPGP-QGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGP------- 837

Query: 570 DLIVPEQCRCADTRPGSEQ---PPLGGAASPEVLAPVSKEA--ADLAPTGPSPRPGP-GL 623
             +V  Q    +T P  E+    P G      +     KE    D  P G   + GP GL
Sbjct: 838 PGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGL 897

Query: 624 LLDVCTKDL-ADAPAEELQEKGSPAGPPPSQGQPAAR 659
                 + L   A    L+    P+GPP   G P  R
Sbjct: 898 RGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGER 934



 Score = 31.2 bits (69), Expect = 6.6
 Identities = 27/112 (24%), Positives = 43/112 (38%), Gaps = 12/112 (10%)

Query: 55  GADGPPAPPGAP-------QAPSPPQGSPQDQHHFLRSSVRPQSKRPRKDPPSAVGSGNA 107
           G+DG P PPG          +    +G           ++  Q++   + PP  +  G  
Sbjct: 352 GSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPM--GYT 409

Query: 108 GGSGPRGK-GAEGGGSSSGNVSGVAPAAPAG--GSRSSSRNLGSSGGEKEEG 156
           G  GP G+ G+ G    SG++    P  P G  G    +   G +G +   G
Sbjct: 410 GRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARG 461


>gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein
           [Homo sapiens]
          Length = 1629

 Score = 46.6 bits (109), Expect = 2e-04
 Identities = 44/165 (26%), Positives = 58/165 (35%), Gaps = 18/165 (10%)

Query: 8   GGSGEDGLKKLGKRAADEESLEGEGAGGADAAEESSGTKRDEKTPRAGADGPPAPPG--- 64
           G SGE G + L  ++         G  G      ++G    + T  +G DGP  PPG   
Sbjct: 713 GASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGT--SGGDGPHGPPGERG 770

Query: 65  --APQA----------PSPPQGSPQDQHHFLRSSVRPQSKRPRKDPPSAVG-SGNAGGSG 111
              PQ           P PP       H   R  V  Q K     PP  VG  G AG +G
Sbjct: 771 LPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETG 830

Query: 112 PRGKGAEGGGSSSGNVSGVAPAAPAGGSRSSSRNLGSSGGEKEEG 156
           P G+    G        G+   A   G++      G+ G +   G
Sbjct: 831 PMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAG 875



 Score = 41.6 bits (96), Expect = 0.005
 Identities = 37/132 (28%), Positives = 43/132 (32%), Gaps = 6/132 (4%)

Query: 31   EGAGGADAAEESSGTKRDEKTPRAGADGPPAPPGAPQAPSPPQGSPQDQHHFLRSSVRPQ 90
            +G  GA   +   G K DE T   G +GPP P G    P P     +           P 
Sbjct: 1018 DGEPGARGPQGHFGAKGDEGT--RGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPP 1075

Query: 91   SKRPRKDPPSAVGS----GNAGGSGPRGKGAEGGGSSSGNVSGVAPAAPAGGSRSSSRNL 146
              R    P  A G     G  G  GP G+  E G S S  + G        G R      
Sbjct: 1076 GPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGES 1135

Query: 147  GSSGGEKEEGKK 158
            G  G     G K
Sbjct: 1136 GQPGEPGPPGPK 1147



 Score = 41.6 bits (96), Expect = 0.005
 Identities = 52/172 (30%), Positives = 64/172 (37%), Gaps = 36/172 (20%)

Query: 6    GDGGS----GEDGLK-KLGKRAADEESLEGEGAGGADAAEESSGTKRDEKTPRAGADGPP 60
            G+ GS    GE G+K   G+R    ES    G  G        G   D+     G  G P
Sbjct: 1109 GESGSPGIQGEPGVKGPRGERGEKGES----GQPGEPGPPGPKGPTGDD-----GPKGNP 1159

Query: 61   APPGAPQAPSPP-QGSPQDQHHFLRSSV------RPQSKRPRKD--PPSAVGS-GNAGGS 110
             P G P  P PP +G P+ Q              +P S  P  +  PP  +G  G AG  
Sbjct: 1160 GPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSP 1219

Query: 111  GPRG-------KGAEGGGSSSGNVSGVAPAAPAG-----GSRSSSRNLGSSG 150
            G  G       KG  G   + G    V PA PAG     G R    ++G  G
Sbjct: 1220 GSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQG 1271



 Score = 40.4 bits (93), Expect = 0.011
 Identities = 45/176 (25%), Positives = 60/176 (34%), Gaps = 28/176 (15%)

Query: 8    GGSGEDGLKKLGKRAADEESLEGEGAG-GADAAEESSGTKRDEKTP----RAGADGPPAP 62
            G  G+DG   L +    E  L G   G G    E  SG      +P     AG+ GP  P
Sbjct: 866  GAPGKDGPAGL-RGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGP 924

Query: 63   PGAPQAPSPPQGSPQDQHHFLRSSVRPQSKRPRKDPPSAVG----SGNAGGSGPRG---- 114
            PG P    PP  + +      +  + P  +   + P    G     G AG  G +G    
Sbjct: 925  PGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGD 984

Query: 115  ---KGAEGGGSSSGNVSGVAPAAPAG-----------GSRSSSRNLGSSGGEKEEG 156
               KG +G     G      P  P G           G+R    + G+ G E   G
Sbjct: 985  PGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRG 1040



 Score = 37.0 bits (84), Expect = 0.12
 Identities = 37/130 (28%), Positives = 46/130 (35%), Gaps = 18/130 (13%)

Query: 31   EGAGGADAAEESSGTKRDEKTPRAGADGPPAPPGAPQAPSPPQGSPQDQHHFLRSSVRPQ 90
            +G  G        G K +   P  G  GPP P G P     P+G+P            P 
Sbjct: 1117 QGEPGVKGPRGERGEKGESGQP--GEPGPPGPKG-PTGDDGPKGNPG-----------PV 1162

Query: 91   SKRPRKDPPSAVGS-GNAGGSGPRGKGAEGGGSSSGNVSGV-APAAPAG--GSRSSSRNL 146
                   PP   G  G  G  G RG+  E G   S   +G   P  P G  G   S  + 
Sbjct: 1163 GFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSE 1222

Query: 147  GSSGGEKEEG 156
            G  GG+  +G
Sbjct: 1223 GRQGGKGAKG 1232



 Score = 36.6 bits (83), Expect = 0.16
 Identities = 39/169 (23%), Positives = 52/169 (30%), Gaps = 14/169 (8%)

Query: 6    GDGGSGEDGLKKLGKRAADEESLEGEGAGGADAAEESSGTKRDEKTP----RAGADGPPA 61
            G G  G+ G      +          G  G D      G+   +  P    +AG  GP  
Sbjct: 1227 GKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVG 1286

Query: 62   PPGAPQAPSPPQGSPQDQHHFLRSSVRPQSKRPRKDP---PSAVGS-------GNAGGSG 111
            PPG P          +  H  L   + P  ++  K     P   GS       G  G SG
Sbjct: 1287 PPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASG 1346

Query: 112  PRGKGAEGGGSSSGNVSGVAPAAPAGGSRSSSRNLGSSGGEKEEGKKVR 160
            P G G   G        G   A   GG +      G  G     G+ ++
Sbjct: 1347 PIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQ 1395



 Score = 36.2 bits (82), Expect = 0.20
 Identities = 38/138 (27%), Positives = 52/138 (37%), Gaps = 14/138 (10%)

Query: 32  GAGGAD-----AAEESSGTKRDEKTPRAGADGPPAPPGAPQAPSP--PQGSPQDQHHFLR 84
           G+GG D     AA+E+      ++  R    GPP P G    P P    GSP  +     
Sbjct: 350 GSGGGDKGPVVAAQEAQAQAILQQA-RLALRGPPGPMGYTGRPGPLGQPGSPGLKGE--S 406

Query: 85  SSVRPQSKRPRK---DPPSAVG-SGNAGGSGPRGKGAEGGGSSSGNVSGVAPAAPAGGSR 140
             + PQ  R  +    PP   G  G AG  G RG   + G        G+       G R
Sbjct: 407 GDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHR 466

Query: 141 SSSRNLGSSGGEKEEGKK 158
             +   G  G   E+G++
Sbjct: 467 GDTGAQGLPGPPGEDGER 484



 Score = 35.4 bits (80), Expect = 0.35
 Identities = 48/161 (29%), Positives = 58/161 (36%), Gaps = 25/161 (15%)

Query: 8   GGSGEDGLKKLGKRAADEESLEGE-GAGGADAAEESSGTKRD--EKTPRA--GADGPPA- 61
           G  G DGL  L      E+   G+ GA G        G + D  E  PR   G  GP   
Sbjct: 449 GDRGFDGLPGL----PGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGL 504

Query: 62  --PPGAPQAPSPPQGSPQDQHHFLRSSVRPQSKRPRKDPPSAVGS-GNAGGSGPRG---- 114
             P G P  P PP     D     + S+ PQ +     PP   G+ G  G  GP+G    
Sbjct: 505 LGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGE---PGPPGQQGTPGTQGLPGPQGAIGP 561

Query: 115 ---KGAEGGGSSSGNVSGVAPAAPAG--GSRSSSRNLGSSG 150
              KG +G     G      P    G  G   +  N G SG
Sbjct: 562 HGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSG 602



 Score = 35.4 bits (80), Expect = 0.35
 Identities = 41/150 (27%), Positives = 51/150 (34%), Gaps = 26/150 (17%)

Query: 31  EGAGGADAAEESSGTKRDEKTPRAGADGPPAPPGA--PQAPSPPQGSPQDQHHFLRSSVR 88
           +G  G+   +   G    + TP  G  G P P GA  P     PQG P      +  S  
Sbjct: 526 QGPKGSLGPQGEPGPPGQQGTP--GTQGLPGPQGAIGPHGEKGPQGKPGLPG--MPGSDG 581

Query: 89  PQSKRPRKDPPSAVGSGNAGGSGPRG----------KGAEG--------GGSSSGNVSGV 130
           P     ++ PP     GN G SGP+G          KG +G        G        G 
Sbjct: 582 PPGHPGKEGPPGT--KGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGF 639

Query: 131 APAAPAGGSRSSSRNLGSSGGEKEEGKKVR 160
                  G R      GS G +  EG K R
Sbjct: 640 KGDIGVKGDRGEVGVPGSRGEDGPEGPKGR 669



 Score = 34.3 bits (77), Expect = 0.78
 Identities = 33/113 (29%), Positives = 38/113 (33%), Gaps = 13/113 (11%)

Query: 55   GADGPPAPPGAPQAPSPP--------QGSPQDQHHFLRSSVR-PQSKRPRKDPPSAVGS- 104
            GADGP  PPG      PP         GSP  Q       V+ P+ +R  K      G  
Sbjct: 1085 GADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGE---PGVKGPRGERGEKGESGQPGEP 1141

Query: 105  GNAGGSGPRGKGAEGGGSSSGNVSGVAPAAPAGGSRSSSRNLGSSGGEKEEGK 157
            G  G  GP G     G        G       GG R      G  G + E G+
Sbjct: 1142 GPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQ 1194



 Score = 33.9 bits (76), Expect = 1.0
 Identities = 32/115 (27%), Positives = 37/115 (32%), Gaps = 10/115 (8%)

Query: 54  AGADGPPAPPGAPQAPSPP--QGSPQDQHHFLRSSVRPQSKRPRKDPPSAVGS------- 104
           AG  GP    G P  P PP  QG P                 P KD P+ +         
Sbjct: 826 AGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGL 885

Query: 105 -GNAGGSGPRGKGAEGGGSSSGNVSGVAPAAPAGGSRSSSRNLGSSGGEKEEGKK 158
            G AGG G +G     G        G   AA +GG        G  G     G+K
Sbjct: 886 PGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEK 940



 Score = 32.3 bits (72), Expect = 3.0
 Identities = 58/217 (26%), Positives = 72/217 (33%), Gaps = 27/217 (12%)

Query: 452 SGQGTARGQVKCPRSGAEGKGVGRPPPAADALQSSGESSPESAPGEGAALSLSSPDAPDR 511
           SG+  ARG      SG  G    R P         G+  P  A G+  A   S  D P  
Sbjct: 715 SGEKGARGL-----SGKSGPRGERGPTGP-----RGQRGPRGATGKSGAKGTSGGDGPHG 764

Query: 512 PPPRHQDTGPCLEKTPAEGRDSPTREPG--ALPCACGQLPDLEDELSLLDPLPRYLKSCQ 569
           PP      GP        G   P   PG   LP   GQ  ++  +     P P       
Sbjct: 765 PPGERGLPGP-QGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGP------- 816

Query: 570 DLIVPEQCRCADTRPGSEQ---PPLGGAASPEVLAPVSKEA--ADLAPTGPSPRPGP-GL 623
             +V  Q    +T P  E+    P G      +     KE    D  P G   + GP GL
Sbjct: 817 PGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGL 876

Query: 624 LLDVCTKDL-ADAPAEELQEKGSPAGPPPSQGQPAAR 659
                 + L   A    L+    P+GPP   G P  R
Sbjct: 877 RGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGER 913



 Score = 31.2 bits (69), Expect = 6.6
 Identities = 27/112 (24%), Positives = 43/112 (38%), Gaps = 12/112 (10%)

Query: 55  GADGPPAPPGAP-------QAPSPPQGSPQDQHHFLRSSVRPQSKRPRKDPPSAVGSGNA 107
           G+DG P PPG          +    +G           ++  Q++   + PP  +  G  
Sbjct: 331 GSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPM--GYT 388

Query: 108 GGSGPRGK-GAEGGGSSSGNVSGVAPAAPAG--GSRSSSRNLGSSGGEKEEG 156
           G  GP G+ G+ G    SG++    P  P G  G    +   G +G +   G
Sbjct: 389 GRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARG 440


>gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein
           [Homo sapiens]
          Length = 1736

 Score = 46.6 bits (109), Expect = 2e-04
 Identities = 44/165 (26%), Positives = 58/165 (35%), Gaps = 18/165 (10%)

Query: 8   GGSGEDGLKKLGKRAADEESLEGEGAGGADAAEESSGTKRDEKTPRAGADGPPAPPG--- 64
           G SGE G + L  ++         G  G      ++G    + T  +G DGP  PPG   
Sbjct: 820 GASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGT--SGGDGPHGPPGERG 877

Query: 65  --APQA----------PSPPQGSPQDQHHFLRSSVRPQSKRPRKDPPSAVG-SGNAGGSG 111
              PQ           P PP       H   R  V  Q K     PP  VG  G AG +G
Sbjct: 878 LPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETG 937

Query: 112 PRGKGAEGGGSSSGNVSGVAPAAPAGGSRSSSRNLGSSGGEKEEG 156
           P G+    G        G+   A   G++      G+ G +   G
Sbjct: 938 PMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAG 982



 Score = 41.6 bits (96), Expect = 0.005
 Identities = 37/132 (28%), Positives = 43/132 (32%), Gaps = 6/132 (4%)

Query: 31   EGAGGADAAEESSGTKRDEKTPRAGADGPPAPPGAPQAPSPPQGSPQDQHHFLRSSVRPQ 90
            +G  GA   +   G K DE T   G +GPP P G    P P     +           P 
Sbjct: 1125 DGEPGARGPQGHFGAKGDEGT--RGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPP 1182

Query: 91   SKRPRKDPPSAVGS----GNAGGSGPRGKGAEGGGSSSGNVSGVAPAAPAGGSRSSSRNL 146
              R    P  A G     G  G  GP G+  E G S S  + G        G R      
Sbjct: 1183 GPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGES 1242

Query: 147  GSSGGEKEEGKK 158
            G  G     G K
Sbjct: 1243 GQPGEPGPPGPK 1254



 Score = 41.6 bits (96), Expect = 0.005
 Identities = 52/172 (30%), Positives = 64/172 (37%), Gaps = 36/172 (20%)

Query: 6    GDGGS----GEDGLK-KLGKRAADEESLEGEGAGGADAAEESSGTKRDEKTPRAGADGPP 60
            G+ GS    GE G+K   G+R    ES    G  G        G   D+     G  G P
Sbjct: 1216 GESGSPGIQGEPGVKGPRGERGEKGES----GQPGEPGPPGPKGPTGDD-----GPKGNP 1266

Query: 61   APPGAPQAPSPP-QGSPQDQHHFLRSSV------RPQSKRPRKD--PPSAVGS-GNAGGS 110
             P G P  P PP +G P+ Q              +P S  P  +  PP  +G  G AG  
Sbjct: 1267 GPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSP 1326

Query: 111  GPRG-------KGAEGGGSSSGNVSGVAPAAPAG-----GSRSSSRNLGSSG 150
            G  G       KG  G   + G    V PA PAG     G R    ++G  G
Sbjct: 1327 GSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQG 1378



 Score = 40.4 bits (93), Expect = 0.011
 Identities = 45/176 (25%), Positives = 60/176 (34%), Gaps = 28/176 (15%)

Query: 8    GGSGEDGLKKLGKRAADEESLEGEGAG-GADAAEESSGTKRDEKTP----RAGADGPPAP 62
            G  G+DG   L +    E  L G   G G    E  SG      +P     AG+ GP  P
Sbjct: 973  GAPGKDGPAGL-RGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGP 1031

Query: 63   PGAPQAPSPPQGSPQDQHHFLRSSVRPQSKRPRKDPPSAVG----SGNAGGSGPRG---- 114
            PG P    PP  + +      +  + P  +   + P    G     G AG  G +G    
Sbjct: 1032 PGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGD 1091

Query: 115  ---KGAEGGGSSSGNVSGVAPAAPAG-----------GSRSSSRNLGSSGGEKEEG 156
               KG +G     G      P  P G           G+R    + G+ G E   G
Sbjct: 1092 PGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRG 1147



 Score = 37.0 bits (84), Expect = 0.12
 Identities = 37/130 (28%), Positives = 46/130 (35%), Gaps = 18/130 (13%)

Query: 31   EGAGGADAAEESSGTKRDEKTPRAGADGPPAPPGAPQAPSPPQGSPQDQHHFLRSSVRPQ 90
            +G  G        G K +   P  G  GPP P G P     P+G+P            P 
Sbjct: 1224 QGEPGVKGPRGERGEKGESGQP--GEPGPPGPKG-PTGDDGPKGNPG-----------PV 1269

Query: 91   SKRPRKDPPSAVGS-GNAGGSGPRGKGAEGGGSSSGNVSGV-APAAPAG--GSRSSSRNL 146
                   PP   G  G  G  G RG+  E G   S   +G   P  P G  G   S  + 
Sbjct: 1270 GFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSE 1329

Query: 147  GSSGGEKEEG 156
            G  GG+  +G
Sbjct: 1330 GRQGGKGAKG 1339



 Score = 36.6 bits (83), Expect = 0.16
 Identities = 39/169 (23%), Positives = 52/169 (30%), Gaps = 14/169 (8%)

Query: 6    GDGGSGEDGLKKLGKRAADEESLEGEGAGGADAAEESSGTKRDEKTP----RAGADGPPA 61
            G G  G+ G      +          G  G D      G+   +  P    +AG  GP  
Sbjct: 1334 GKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVG 1393

Query: 62   PPGAPQAPSPPQGSPQDQHHFLRSSVRPQSKRPRKDP---PSAVGS-------GNAGGSG 111
            PPG P          +  H  L   + P  ++  K     P   GS       G  G SG
Sbjct: 1394 PPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASG 1453

Query: 112  PRGKGAEGGGSSSGNVSGVAPAAPAGGSRSSSRNLGSSGGEKEEGKKVR 160
            P G G   G        G   A   GG +      G  G     G+ ++
Sbjct: 1454 PIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQ 1502



 Score = 36.2 bits (82), Expect = 0.20
 Identities = 38/138 (27%), Positives = 52/138 (37%), Gaps = 14/138 (10%)

Query: 32  GAGGAD-----AAEESSGTKRDEKTPRAGADGPPAPPGAPQAPSP--PQGSPQDQHHFLR 84
           G+GG D     AA+E+      ++  R    GPP P G    P P    GSP  +     
Sbjct: 457 GSGGGDKGPVVAAQEAQAQAILQQA-RLALRGPPGPMGYTGRPGPLGQPGSPGLKGE--S 513

Query: 85  SSVRPQSKRPRK---DPPSAVG-SGNAGGSGPRGKGAEGGGSSSGNVSGVAPAAPAGGSR 140
             + PQ  R  +    PP   G  G AG  G RG   + G        G+       G R
Sbjct: 514 GDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHR 573

Query: 141 SSSRNLGSSGGEKEEGKK 158
             +   G  G   E+G++
Sbjct: 574 GDTGAQGLPGPPGEDGER 591



 Score = 35.4 bits (80), Expect = 0.35
 Identities = 48/161 (29%), Positives = 58/161 (36%), Gaps = 25/161 (15%)

Query: 8   GGSGEDGLKKLGKRAADEESLEGE-GAGGADAAEESSGTKRD--EKTPRA--GADGPPA- 61
           G  G DGL  L      E+   G+ GA G        G + D  E  PR   G  GP   
Sbjct: 556 GDRGFDGLPGL----PGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGL 611

Query: 62  --PPGAPQAPSPPQGSPQDQHHFLRSSVRPQSKRPRKDPPSAVGS-GNAGGSGPRG---- 114
             P G P  P PP     D     + S+ PQ +     PP   G+ G  G  GP+G    
Sbjct: 612 LGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGE---PGPPGQQGTPGTQGLPGPQGAIGP 668

Query: 115 ---KGAEGGGSSSGNVSGVAPAAPAG--GSRSSSRNLGSSG 150
              KG +G     G      P    G  G   +  N G SG
Sbjct: 669 HGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSG 709



 Score = 35.4 bits (80), Expect = 0.35
 Identities = 41/150 (27%), Positives = 51/150 (34%), Gaps = 26/150 (17%)

Query: 31  EGAGGADAAEESSGTKRDEKTPRAGADGPPAPPGA--PQAPSPPQGSPQDQHHFLRSSVR 88
           +G  G+   +   G    + TP  G  G P P GA  P     PQG P      +  S  
Sbjct: 633 QGPKGSLGPQGEPGPPGQQGTP--GTQGLPGPQGAIGPHGEKGPQGKPGLPG--MPGSDG 688

Query: 89  PQSKRPRKDPPSAVGSGNAGGSGPRG----------KGAEG--------GGSSSGNVSGV 130
           P     ++ PP     GN G SGP+G          KG +G        G        G 
Sbjct: 689 PPGHPGKEGPPGT--KGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGF 746

Query: 131 APAAPAGGSRSSSRNLGSSGGEKEEGKKVR 160
                  G R      GS G +  EG K R
Sbjct: 747 KGDIGVKGDRGEVGVPGSRGEDGPEGPKGR 776



 Score = 34.3 bits (77), Expect = 0.78
 Identities = 33/113 (29%), Positives = 38/113 (33%), Gaps = 13/113 (11%)

Query: 55   GADGPPAPPGAPQAPSPP--------QGSPQDQHHFLRSSVR-PQSKRPRKDPPSAVGS- 104
            GADGP  PPG      PP         GSP  Q       V+ P+ +R  K      G  
Sbjct: 1192 GADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGE---PGVKGPRGERGEKGESGQPGEP 1248

Query: 105  GNAGGSGPRGKGAEGGGSSSGNVSGVAPAAPAGGSRSSSRNLGSSGGEKEEGK 157
            G  G  GP G     G        G       GG R      G  G + E G+
Sbjct: 1249 GPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQ 1301



 Score = 33.9 bits (76), Expect = 1.0
 Identities = 32/115 (27%), Positives = 37/115 (32%), Gaps = 10/115 (8%)

Query: 54   AGADGPPAPPGAPQAPSPP--QGSPQDQHHFLRSSVRPQSKRPRKDPPSAVGS------- 104
            AG  GP    G P  P PP  QG P                 P KD P+ +         
Sbjct: 933  AGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGL 992

Query: 105  -GNAGGSGPRGKGAEGGGSSSGNVSGVAPAAPAGGSRSSSRNLGSSGGEKEEGKK 158
             G AGG G +G     G        G   AA +GG        G  G     G+K
Sbjct: 993  PGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEK 1047



 Score = 32.3 bits (72), Expect = 3.0
 Identities = 58/217 (26%), Positives = 72/217 (33%), Gaps = 27/217 (12%)

Query: 452  SGQGTARGQVKCPRSGAEGKGVGRPPPAADALQSSGESSPESAPGEGAALSLSSPDAPDR 511
            SG+  ARG      SG  G    R P         G+  P  A G+  A   S  D P  
Sbjct: 822  SGEKGARGL-----SGKSGPRGERGPTGP-----RGQRGPRGATGKSGAKGTSGGDGPHG 871

Query: 512  PPPRHQDTGPCLEKTPAEGRDSPTREPG--ALPCACGQLPDLEDELSLLDPLPRYLKSCQ 569
            PP      GP        G   P   PG   LP   GQ  ++  +     P P       
Sbjct: 872  PPGERGLPGP-QGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGP------- 923

Query: 570  DLIVPEQCRCADTRPGSEQ---PPLGGAASPEVLAPVSKEA--ADLAPTGPSPRPGP-GL 623
              +V  Q    +T P  E+    P G      +     KE    D  P G   + GP GL
Sbjct: 924  PGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGL 983

Query: 624  LLDVCTKDL-ADAPAEELQEKGSPAGPPPSQGQPAAR 659
                  + L   A    L+    P+GPP   G P  R
Sbjct: 984  RGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGER 1020



 Score = 31.2 bits (69), Expect = 6.6
 Identities = 27/112 (24%), Positives = 43/112 (38%), Gaps = 12/112 (10%)

Query: 55  GADGPPAPPGAP-------QAPSPPQGSPQDQHHFLRSSVRPQSKRPRKDPPSAVGSGNA 107
           G+DG P PPG          +    +G           ++  Q++   + PP  +  G  
Sbjct: 438 GSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPM--GYT 495

Query: 108 GGSGPRGK-GAEGGGSSSGNVSGVAPAAPAG--GSRSSSRNLGSSGGEKEEG 156
           G  GP G+ G+ G    SG++    P  P G  G    +   G +G +   G
Sbjct: 496 GRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARG 547


>gi|148612809 WNK lysine deficient protein kinase 1 [Homo sapiens]
          Length = 2382

 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 70/309 (22%), Positives = 120/309 (38%), Gaps = 44/309 (14%)

Query: 898  SENQSHNVCSFSILSNSSVTGRGSFRPIQSSLTKAALSRPI--------VPKVLPPQAT- 948
            +++Q H V   S    S   G+   +P  SSLT  + S+PI        + +  PPQ T 
Sbjct: 700  AQSQPHGVYPPS----SVAQGQSQGQPSSSSLTGVSSSQPIQHPQQQQGIQQTAPPQQTV 755

Query: 949  --SHLASAIDLAATSAGILSGNPLPALDTEGLSGIS-------PLSSDEVTGAISGQDST 999
              S   ++    AT+A  +S    P +  +  +G         P    E    ++ Q S 
Sbjct: 756  QYSLSQTSTSSEATTAQPVSQPQAPQVLPQVSAGKQLPVSQPVPTIQGEPQIPVATQPSV 815

Query: 1000 GTHQDGDTLPTVGGSDPFVSIPSRP-EQEPVADSFQGSSVLSLSELPKAPLQNGLSIPLS 1058
                 G     VG   P   +P  P  Q P++     ++    S LP   +  G++ PL 
Sbjct: 816  VPVHSGAHFLPVGQPLPTPLLPQYPVSQIPISTPHVSTAQTGFSSLP-ITMAAGITQPLL 874

Query: 1059 SSESSSTRLSPPDVSALLDISLPGPPEDALSQGEPATHISDSIIEIAISSGQYGEGVPLS 1118
            +  SS+T  + P VS ++   LP       +  +P T +   +    +       G+P  
Sbjct: 875  TLASSATTAAIPGVSTVVPSQLP-------TLLQPVTQLPSQVHPQLLQPAVQSMGIP-- 925

Query: 1119 PAKLNGSDSSKSLPSPSSSPQPHWIASPTHDPQWYPSDSTDSSLSS-----LFASFISPE 1173
                  ++  ++   P SS    +   P   P  YP DS  +  S+     + ++ +SP 
Sbjct: 926  ------ANLGQAAEVPLSSGDVLYQGFPPRLPPQYPGDSNIAPSSNVASVCIHSTVLSPP 979

Query: 1174 KSRKMLPTP 1182
               ++L TP
Sbjct: 980  MPTEVLATP 988



 Score = 32.3 bits (72), Expect = 3.0
 Identities = 34/146 (23%), Positives = 52/146 (35%), Gaps = 11/146 (7%)

Query: 59  PPAPPGAPQAPSP---PQGSPQDQHHFLRSSVRPQSKRPRKDPPSAVGSGNAGGSGPRGK 115
           P  P   PQ   P   PQ +P + H    +     + +  + PP+A   G    +GP   
Sbjct: 96  PGLPLSLPQPSIPAAVPQSAPPEPHRE-ETVTATATSQVAQQPPAAAAPGEQAVAGPAPS 154

Query: 116 GAEGGGSSSGNVSGVAPAAPAGGSRSSSRNLGSSGGEKEEGKKVRRQWESWSTEDKNTFF 175
                 S    VS   P+             GS GG  +E ++ R Q +    E+  T  
Sbjct: 155 TVPSSTSKDRPVS--QPSLVGSKEEPPPARSGSGGGSAKEPQEERSQQQD-DIEELETKA 211

Query: 176 EGLYEHGK----DFEAIQNNIALKYK 197
            G+   G+    D E  + +    YK
Sbjct: 212 VGMSNDGRFLKFDIEIGRGSFKTVYK 237


>gi|239743232 PREDICTED: hypothetical protein XP_002342775 [Homo
            sapiens]
          Length = 834

 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 99/463 (21%), Positives = 160/463 (34%), Gaps = 40/463 (8%)

Query: 736  LISTEVNPKLALEANTISTASVRPAQEEQSMTPPGKVVTVSSRSPRCPRNQASLRSSKTF 795
            L++   NP L       +  S+ P  E       G   T +   P+ P     L  S++ 
Sbjct: 173  LLAPSTNPLLESLKKMQTPPSLPPCPESA-----GAATTEALSPPKTPNLLPPLGLSQSG 227

Query: 796  PPSSAPCSSGLRNPPRPL--LVPGPSSTGSNDSDG-GLFAVPTTLPPNSRHGKLFSPSKE 852
            PP   P  S   NPP  L  L+P PS   + D+         TT  P +      SP+ +
Sbjct: 228  PPGLLPSPSFDSNPPTTLLGLIPAPSMVPATDTKAPPTLQAETTTKPQATSAP--SPAPK 285

Query: 853  AELTFRQHLNSISMQSDFFLPKPRKLRNRHLRKPLVVQRTLLPRPSENQSHNVCSFSILS 912
                F     S S  +         +       P   ++     P  + S    S S L 
Sbjct: 286  QSFLFGTQNTSPSSPAAPAASSASPMFKPIFTAPPKSEKEGPTPPGPSVSATAPSSSSLP 345

Query: 913  NSSVTGRGSFRPIQSSLTKAALSRPIVPKVLPPQATSHLASAIDLAATSAGILSGNPLPA 972
             ++ T   +F+P+ SS+   A S P+ P     Q T+   +    A    G+ S     A
Sbjct: 346  TTTSTTAPTFQPVFSSMGPPA-SVPL-PAPFFKQTTTPATAPTTTAPLFTGLASATSAVA 403

Query: 973  LDTEGLSGISPLSSDEVTGAISGQDSTGTHQDGDTLPTVGGSDPFVSIPSRPEQEPVADS 1032
              T         S       I+   S+       T      S PF+     P+    + +
Sbjct: 404  PITSASPSTDSASKPAFGFGINSVSSSSVSTTTST--ATAASQPFLF--GAPQASAASFT 459

Query: 1033 FQGSSVLSLSELPKAPLQNGLSIPLSSSESSSTRLSPPDVSALLDISLPGPPEDALSQGE 1092
                S+    + P  P    ++   + S+S  T +     S+  D S  G     L+   
Sbjct: 460  PAMGSIFQFGKPPALPTTTTVT---TFSQSLPTAVPTATSSSAADFSGFG---STLATSA 513

Query: 1093 PATHISDSIIEIAISSGQYGEGVPLSPAKLNGSDSSKSLPS-PSSSPQPHW--------- 1142
            PAT    ++     S+  +   +P       GS +   LPS P ++PQP +         
Sbjct: 514  PATSSQPTLTFSNTSTPTF--NIPF------GSSAKSPLPSYPGANPQPAFGAAEGQPPG 565

Query: 1143 IASPTHDPQWYPSDSTDSSLSSLFASFISPEKSRKMLPTPIGT 1185
             A P   P +  S +  +S +   A   +P    K++P  + T
Sbjct: 566  AAKPALTPSFGSSFTFGNSAAPAAAPTPAPPSMIKIVPAHVPT 608


>gi|29725624 collagen, type XXIII, alpha 1 [Homo sapiens]
          Length = 540

 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 40/133 (30%), Positives = 54/133 (40%), Gaps = 13/133 (9%)

Query: 32  GAGGADAAEESSGTKRDEKTPRAGADGPPAPPGAPQAPSPPQGSPQDQHHFLRSSVRPQS 91
           G  G   A    G + D+   + GA GPP PPG P A  PP  + +D     R +  P  
Sbjct: 160 GPKGEKGAPGDFGPRGDQG--QDGAAGPPGPPGPPGARGPPGDTGKDGP---RGAQGPAG 214

Query: 92  KRPRKDPPSAVGSGNAGGSGPRGK-GAEGGGSSSGNVSGVAPAAPAG-----GSRSSSRN 145
             P+ +P      G  G  GP+G+ G  G     G  S   P  P G     G R  +  
Sbjct: 215 --PKGEPGQDGEMGPKGPPGPKGEPGVPGKKGDDGTPSQPGPPGPKGEPGSMGPRGENGV 272

Query: 146 LGSSGGEKEEGKK 158
            G+ G + E G +
Sbjct: 273 DGAPGPKGEPGHR 285



 Score = 32.7 bits (73), Expect = 2.3
 Identities = 45/160 (28%), Positives = 57/160 (35%), Gaps = 18/160 (11%)

Query: 8   GGSGEDGLKKLGKRAADEESLEG-EGAGG--ADAAEESSGTKRDEKTPRAGADGPPAPPG 64
           G  GE G   L K  A E  L G  GA G   +  E +S + ++         GPP PPG
Sbjct: 360 GDPGEPGPAGL-KGEAGEMGLSGLPGADGLKGEKGESASDSLQESLAQLIVEPGPPGPPG 418

Query: 65  AP-----QAPSPPQGSPQDQHHFLRSSVRPQSKRPRK-DPPSAVGSGNAGGSGPRGKGAE 118
            P     Q    P+G    +     S  R  S  P    PP  +G    G  G +G+  E
Sbjct: 419 PPGPMGLQGIQGPKGLDGAKGEKGASGERGPSGLPGPVGPPGLIGL--PGTKGEKGRPGE 476

Query: 119 GGGSSSGNVSGVAPAAPAGGSRSSSRNLGSSGGEKEEGKK 158
            G      + G        G RS     G  G    +G K
Sbjct: 477 PG------LDGFPGPRGEKGDRSERGEKGERGVPGRKGVK 510


>gi|41349486 proline-rich protein BstNI subfamily 1 isoform 3
           preproprotein [Homo sapiens]
          Length = 178

 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 34/102 (33%), Positives = 41/102 (40%), Gaps = 10/102 (9%)

Query: 51  TPRAG--ADGPPAPPGAPQAPSP-----PQGSPQDQHHFLRSSVRPQSKRPRKDPPSAVG 103
           +P+ G    GPP PPG PQ P P     PQG P             +S+ PR  P    G
Sbjct: 40  SPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQG 99

Query: 104 SGNAGGSGPRGKGAEGGGSSSGNVSGVAPAAPAGGSRSSSRN 145
               GG  P+G  A+GG  S    S   P  P G  +    N
Sbjct: 100 PPPQGGK-PQGPPAQGGSKSQSARS--PPGKPQGPPQQEGNN 138



 Score = 39.7 bits (91), Expect = 0.019
 Identities = 33/100 (33%), Positives = 41/100 (41%), Gaps = 23/100 (23%)

Query: 52  PRAGADGP--PAPPGAPQAPSP----------PQGSPQDQHHFLRSSVRPQSKRPRKDPP 99
           P  G + P  P PPG PQ P P          P G PQ           PQ  +P + PP
Sbjct: 61  PPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQ--------GPPPQGGKP-QGPP 111

Query: 100 SAVGSGNAGGSGPRGKGAEGGGSSSGNVSGVAPAAPAGGS 139
           +  GS +     P GK  +G     GN +   P  PAGG+
Sbjct: 112 AQGGSKSQSARSPPGK-PQGPPQQEGN-NPQGPPPPAGGN 149



 Score = 34.7 bits (78), Expect = 0.60
 Identities = 27/95 (28%), Positives = 35/95 (36%), Gaps = 8/95 (8%)

Query: 47  RDEKTPRAGADGPPAPPGAPQAPSPPQGSPQDQHHFLRSSVRPQSKRPRKDPPSAVGSGN 106
           R  ++P     GPP   G PQ P P QG  + Q      S R    +P + PP   G+  
Sbjct: 88  RSPRSPPGKPQGPPPQGGKPQGP-PAQGGSKSQ------SARSPPGKP-QGPPQQEGNNP 139

Query: 107 AGGSGPRGKGAEGGGSSSGNVSGVAPAAPAGGSRS 141
            G   P G   +   +         P  P GG  S
Sbjct: 140 QGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPS 174



 Score = 30.8 bits (68), Expect = 8.6
 Identities = 25/89 (28%), Positives = 31/89 (34%), Gaps = 21/89 (23%)

Query: 584 PGSEQ-PPLGGAASPEVLAPVSKEAADLAPTGPSPRPGPGLLLDVCTKDLADAPAEELQE 642
           PG  Q PP  G   P+   P  K      P GP P+               D        
Sbjct: 54  PGKPQGPPPQGGNKPQGPPPPGK------PQGPPPQ--------------GDKSRSPRSP 93

Query: 643 KGSPAGPPPSQGQPAARPPKEVPASRLAQ 671
            G P GPPP  G+P   P +    S+ A+
Sbjct: 94  PGKPQGPPPQGGKPQGPPAQGGSKSQSAR 122


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.310    0.130    0.382 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 62,852,327
Number of Sequences: 37866
Number of extensions: 3906671
Number of successful extensions: 37107
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 224
Number of HSP's successfully gapped in prelim test: 1414
Number of HSP's that attempted gapping in prelim test: 22186
Number of HSP's gapped (non-prelim): 12444
length of query: 1269
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1155
effective length of database: 13,930,794
effective search space: 16090067070
effective search space used: 16090067070
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 68 (30.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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