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Search of human proteins with 223633939
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|223633939 solute carrier family 39 (zinc transporter),
member 12 isoform 1 [Homo sapiens]
(691 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|223633939 solute carrier family 39 (zinc transporter), member... 1372 0.0
gi|223633937 solute carrier family 39 (zinc transporter), member... 1282 0.0
gi|115430255 solute carrier family 39 (zinc transporter), member... 290 3e-78
gi|115430259 solute carrier family 39 (zinc transporter), member... 286 6e-77
gi|205830424 solute carrier family 39 (zinc transporter), member... 200 3e-51
gi|190360568 solute carrier family 39 (zinc transporter), member... 200 3e-51
gi|190358541 solute carrier family 39 (zinc transporter), member... 195 1e-49
gi|24586665 solute carrier family 39 (zinc transporter), member ... 181 2e-45
gi|205830403 solute carrier family 39 (zinc transporter), member... 181 2e-45
gi|205830426 solute carrier family 39 (zinc transporter), member... 181 3e-45
gi|205830407 solute carrier family 39 (zinc transporter), member... 180 4e-45
gi|206597541 solute carrier family 39 (metal ion transporter), m... 168 2e-41
gi|206597539 solute carrier family 39 (metal ion transporter), m... 168 2e-41
gi|205830405 solute carrier family 39 (zinc transporter), member... 165 1e-40
gi|187936949 solute carrier family 39 (zinc transporter), member... 161 2e-39
gi|55741750 solute carrier family 39 (zinc transporter), member ... 161 2e-39
gi|153252201 solute carrier family 39 (zinc transporter), member... 156 7e-38
gi|117553619 solute carrier family 39, member 7 [Homo sapiens] 140 5e-33
gi|117553608 solute carrier family 39, member 7 [Homo sapiens] 140 5e-33
gi|153252214 solute carrier family 39 (zinc transporter), member... 128 2e-29
gi|40255101 solute carrier family 39 (zinc transporter), member ... 100 8e-21
gi|190014617 solute carrier family 39 (zinc transporter), member... 97 5e-20
gi|40254928 solute carrier family 39 (zinc transporter), member ... 59 2e-08
gi|156415986 solute carrier family 39 (zinc transporter), member... 46 1e-04
gi|21361423 solute carrier family 39 (zinc transporter), member ... 42 0.002
gi|229577422 solute carrier family 39, member 11 isoform 1 [Homo... 37 0.047
gi|229577418 solute carrier family 39, member 11 isoform 2 [Homo... 35 0.23
gi|205360987 TBP-associated factor 1B [Homo sapiens] 32 1.5
gi|168480072 BCL2-related protein A1 isoform 2 [Homo sapiens] 32 2.0
gi|4757840 BCL2-related protein A1 isoform 1 [Homo sapiens] 32 2.0
>gi|223633939 solute carrier family 39 (zinc transporter), member 12
isoform 1 [Homo sapiens]
Length = 691
Score = 1372 bits (3552), Expect = 0.0
Identities = 691/691 (100%), Positives = 691/691 (100%)
Query: 1 MCFRTKLSVSWVPLFLLLSRVFSTETDKPSAQDSRSRGSSGQPADLLQVLSAGDHPPHNH 60
MCFRTKLSVSWVPLFLLLSRVFSTETDKPSAQDSRSRGSSGQPADLLQVLSAGDHPPHNH
Sbjct: 1 MCFRTKLSVSWVPLFLLLSRVFSTETDKPSAQDSRSRGSSGQPADLLQVLSAGDHPPHNH 60
Query: 61 SRSLIKTLLEKTGCPRRRNGMQGDCNLCFEPDALLLIAGGNFEDQLREEVVQRVSLLLLY 120
SRSLIKTLLEKTGCPRRRNGMQGDCNLCFEPDALLLIAGGNFEDQLREEVVQRVSLLLLY
Sbjct: 61 SRSLIKTLLEKTGCPRRRNGMQGDCNLCFEPDALLLIAGGNFEDQLREEVVQRVSLLLLY 120
Query: 121 YIIHQEEICSSKLNMSNKEYKFYLHSLLSLRQDEDSSFLSQNETEDILAFTRQYFDTSQS 180
YIIHQEEICSSKLNMSNKEYKFYLHSLLSLRQDEDSSFLSQNETEDILAFTRQYFDTSQS
Sbjct: 121 YIIHQEEICSSKLNMSNKEYKFYLHSLLSLRQDEDSSFLSQNETEDILAFTRQYFDTSQS 180
Query: 181 QCMETKTLQKKSGIVSSEGANESTLPQLAAMIITLSLQGVCLGQGNLPSPDYFTEYIFSS 240
QCMETKTLQKKSGIVSSEGANESTLPQLAAMIITLSLQGVCLGQGNLPSPDYFTEYIFSS
Sbjct: 181 QCMETKTLQKKSGIVSSEGANESTLPQLAAMIITLSLQGVCLGQGNLPSPDYFTEYIFSS 240
Query: 241 LNRTNTLRLSELDQLLNTLWTRSTCIKNEKIHQFQRKQNNIITHDQDYSNFSSSMEKESE 300
LNRTNTLRLSELDQLLNTLWTRSTCIKNEKIHQFQRKQNNIITHDQDYSNFSSSMEKESE
Sbjct: 241 LNRTNTLRLSELDQLLNTLWTRSTCIKNEKIHQFQRKQNNIITHDQDYSNFSSSMEKESE 300
Query: 301 DGPVSWDQTCFSARQLVEIFLQKGLSLISKEDFKQMSPGIIQQLLSCSCHLPKDQQAKLP 360
DGPVSWDQTCFSARQLVEIFLQKGLSLISKEDFKQMSPGIIQQLLSCSCHLPKDQQAKLP
Sbjct: 301 DGPVSWDQTCFSARQLVEIFLQKGLSLISKEDFKQMSPGIIQQLLSCSCHLPKDQQAKLP 360
Query: 361 PTTLEKYGYSTVAVTLLTLGSMLGTALVLFHSCEENYRLILQLFVGLAVGTLSGDALLHL 420
PTTLEKYGYSTVAVTLLTLGSMLGTALVLFHSCEENYRLILQLFVGLAVGTLSGDALLHL
Sbjct: 361 PTTLEKYGYSTVAVTLLTLGSMLGTALVLFHSCEENYRLILQLFVGLAVGTLSGDALLHL 420
Query: 421 IPQVLGLHKQEAPEFGHFHESKGHIWKLMGLIGGIHGFFLIEKCFILLVSPNDKQGLSLV 480
IPQVLGLHKQEAPEFGHFHESKGHIWKLMGLIGGIHGFFLIEKCFILLVSPNDKQGLSLV
Sbjct: 421 IPQVLGLHKQEAPEFGHFHESKGHIWKLMGLIGGIHGFFLIEKCFILLVSPNDKQGLSLV 480
Query: 481 NGHVGHSHHLALNSELSDQAGRGKSASTIQLKSPEDSQAAEMPIGSMTASNRKCKAISLL 540
NGHVGHSHHLALNSELSDQAGRGKSASTIQLKSPEDSQAAEMPIGSMTASNRKCKAISLL
Sbjct: 481 NGHVGHSHHLALNSELSDQAGRGKSASTIQLKSPEDSQAAEMPIGSMTASNRKCKAISLL 540
Query: 541 AIMILVGDSLHNFADGLAIGAAFSSSSESGVTTTIAILCHEIPHEMGDFAVLLSSGLSMK 600
AIMILVGDSLHNFADGLAIGAAFSSSSESGVTTTIAILCHEIPHEMGDFAVLLSSGLSMK
Sbjct: 541 AIMILVGDSLHNFADGLAIGAAFSSSSESGVTTTIAILCHEIPHEMGDFAVLLSSGLSMK 600
Query: 601 TAILMNFISSLTAFMGLYIGLSVSADPCVQDWIFTVTAGMFLYLSLVEMLPEMTHVQTQR 660
TAILMNFISSLTAFMGLYIGLSVSADPCVQDWIFTVTAGMFLYLSLVEMLPEMTHVQTQR
Sbjct: 601 TAILMNFISSLTAFMGLYIGLSVSADPCVQDWIFTVTAGMFLYLSLVEMLPEMTHVQTQR 660
Query: 661 PWMMFLLQNFGLILGWLSLLLLAIYEQNIKI 691
PWMMFLLQNFGLILGWLSLLLLAIYEQNIKI
Sbjct: 661 PWMMFLLQNFGLILGWLSLLLLAIYEQNIKI 691
>gi|223633937 solute carrier family 39 (zinc transporter), member 12
isoform 2 [Homo sapiens]
Length = 654
Score = 1282 bits (3317), Expect = 0.0
Identities = 654/691 (94%), Positives = 654/691 (94%), Gaps = 37/691 (5%)
Query: 1 MCFRTKLSVSWVPLFLLLSRVFSTETDKPSAQDSRSRGSSGQPADLLQVLSAGDHPPHNH 60
MCFRTKLSVSWVPLFLLLSRVFSTETDKPSAQDSRSRGSSGQPADLLQVLSAGDHPPHNH
Sbjct: 1 MCFRTKLSVSWVPLFLLLSRVFSTETDKPSAQDSRSRGSSGQPADLLQVLSAGDHPPHNH 60
Query: 61 SRSLIKTLLEKTGCPRRRNGMQGDCNLCFEPDALLLIAGGNFEDQLREEVVQRVSLLLLY 120
SRSLIKTLLEKTGCPRRRNGMQGDCNLCFEPDALLLIAGGNFEDQLREEVVQRVSLLLLY
Sbjct: 61 SRSLIKTLLEKTGCPRRRNGMQGDCNLCFEPDALLLIAGGNFEDQLREEVVQRVSLLLLY 120
Query: 121 YIIHQEEICSSKLNMSNKEYKFYLHSLLSLRQDEDSSFLSQNETEDILAFTRQYFDTSQS 180
YIIHQEEICSSKLNMSNKEYKFYLHSLLSLRQDEDSSFLSQNETEDILAFTRQYFDTSQS
Sbjct: 121 YIIHQEEICSSKLNMSNKEYKFYLHSLLSLRQDEDSSFLSQNETEDILAFTRQYFDTSQS 180
Query: 181 QCMETKTLQKKSGIVSSEGANESTLPQLAAMIITLSLQGVCLGQGNLPSPDYFTEYIFSS 240
QCMETKTLQKKSGIVSSEGANESTLPQLAAMIITLSLQGVCLGQGNLPSPDYFTEYIFSS
Sbjct: 181 QCMETKTLQKKSGIVSSEGANESTLPQLAAMIITLSLQGVCLGQGNLPSPDYFTEYIFSS 240
Query: 241 LNRTNTLRLSELDQLLNTLWTRSTCIKNEKIHQFQRKQNNIITHDQDYSNFSSSMEKESE 300
LNRTNTLRLSELDQLLNTLWTRSTCIKNEKIHQFQRKQNNIITHDQDYSNFSSSMEKESE
Sbjct: 241 LNRTNTLRLSELDQLLNTLWTRSTCIKNEKIHQFQRKQNNIITHDQDYSNFSSSMEKESE 300
Query: 301 DGPVSWDQTCFSARQLVEIFLQKGLSLISKEDFKQMSPGIIQQLLSCSCHLPKDQQAKLP 360
DGPVSWDQTCFSARQLVEIFLQKGLSLISKEDFKQMSPGIIQQLLSCSCHLPKDQQAKLP
Sbjct: 301 DGPVSWDQTCFSARQLVEIFLQKGLSLISKEDFKQMSPGIIQQLLSCSCHLPKDQQAKLP 360
Query: 361 PTTLEKYGYSTVAVTLLTLGSMLGTALVLFHSCEENYRLILQLFVGLAVGTLSGDALLHL 420
PTTLEKYGYSTVAVTLLTLGSMLGTALVLFHSCEENYRLILQLFVGLAVGTLSGDALLHL
Sbjct: 361 PTTLEKYGYSTVAVTLLTLGSMLGTALVLFHSCEENYRLILQLFVGLAVGTLSGDALLHL 420
Query: 421 IPQVLGLHKQEAPEFGHFHESKGHIWKLMGLIGGIHGFFLIEKCFILLVSPNDKQGLSLV 480
IPQVLGLHKQEAPEFGHFHESKGHIWKLMGLIGGIHGFFLIEKCFILLVSPNDK
Sbjct: 421 IPQVLGLHKQEAPEFGHFHESKGHIWKLMGLIGGIHGFFLIEKCFILLVSPNDK------ 474
Query: 481 NGHVGHSHHLALNSELSDQAGRGKSASTIQLKSPEDSQAAEMPIGSMTASNRKCKAISLL 540
KSPEDSQAAEMPIGSMTASNRKCKAISLL
Sbjct: 475 -------------------------------KSPEDSQAAEMPIGSMTASNRKCKAISLL 503
Query: 541 AIMILVGDSLHNFADGLAIGAAFSSSSESGVTTTIAILCHEIPHEMGDFAVLLSSGLSMK 600
AIMILVGDSLHNFADGLAIGAAFSSSSESGVTTTIAILCHEIPHEMGDFAVLLSSGLSMK
Sbjct: 504 AIMILVGDSLHNFADGLAIGAAFSSSSESGVTTTIAILCHEIPHEMGDFAVLLSSGLSMK 563
Query: 601 TAILMNFISSLTAFMGLYIGLSVSADPCVQDWIFTVTAGMFLYLSLVEMLPEMTHVQTQR 660
TAILMNFISSLTAFMGLYIGLSVSADPCVQDWIFTVTAGMFLYLSLVEMLPEMTHVQTQR
Sbjct: 564 TAILMNFISSLTAFMGLYIGLSVSADPCVQDWIFTVTAGMFLYLSLVEMLPEMTHVQTQR 623
Query: 661 PWMMFLLQNFGLILGWLSLLLLAIYEQNIKI 691
PWMMFLLQNFGLILGWLSLLLLAIYEQNIKI
Sbjct: 624 PWMMFLLQNFGLILGWLSLLLLAIYEQNIKI 654
>gi|115430255 solute carrier family 39 (zinc transporter), member 4
isoform 2 [Homo sapiens]
Length = 647
Score = 290 bits (742), Expect = 3e-78
Identities = 210/671 (31%), Positives = 322/671 (47%), Gaps = 66/671 (9%)
Query: 39 SSGQPADLLQVLSAGDHPPHNHSRS-LIKTLLEKTGCPRRRNGMQGDCNLCF-------- 89
++ PA LL +L++G + L+ TL ++ C G C C
Sbjct: 21 TASPPAGLLSLLTSGQGALDQEALGGLLNTLADRVHCAN------GPCGKCLSVEDALGL 74
Query: 90 -EPDALLLIAGGNFEDQLREEVVQRVSLLLLYYIIHQEEICSSKLNMSNKEYKFYLHSLL 148
EP+ L G L V R+S + Y+ + E C + +L +LL
Sbjct: 75 GEPEGSGLPPG----PVLEARYVARLSAAAVLYLSNPEGTCEDARAGLWASHADHLLALL 130
Query: 149 SLRQ--DEDSSFLSQNETEDILAFTRQYFDTSQSQCMETKTLQKKSGIVSSEGANESTLP 206
+ S+L Q R T ++ C++ L +++ + G+ L
Sbjct: 131 ESPKALTPGLSWLLQRMQ------ARAAGQTPKTACVDIPQLLEEAVGAGAPGSAGGVL- 183
Query: 207 QLAAMIITLSLQGVCLGQGNLPSPDYFTEYIFSSLNRTNTLRLSELDQLLNTLWTRSTCI 266
A ++ G C LPSP YF +++F + + L+EL L+ L
Sbjct: 184 ---AALLDHVRSGSCFHA--LPSPQYFVDFVFQQHSSEVPMTLAELSALMQRLGV----- 233
Query: 267 KNEKIHQFQRKQNNIITHDQDYSNFSSSMEKESEDGPVSWDQTCFSARQLVEIFLQKGLS 326
+ H ++ + SSS WD C SAR ++ + +
Sbjct: 234 -GREAHSDHSHRHRGASSRDPVPLISSSNSSSV------WDTVCLSARDVMAAYGLSEQA 286
Query: 327 LISKEDFKQMSPGIIQQLLSCSCHLPKDQQAKLPPTTLEKYGYSTVAVTLLTLGSMLGTA 386
++ E + Q+SP ++QQ LS +C + + E+Y Y ++A L+ L ++ G
Sbjct: 287 GVTPEAWAQLSPALLQQQLSGACTSQSRPPVQDQLSQSERYLYGSLATLLICLCAVFGLL 346
Query: 387 LVLFHSCEENYRLILQLFVGLAVGTLSGDALLHLIPQVLGLHKQEAPEFGHFHESKGHIW 446
L+ C ILQ F+ LAVG L+GDA+LHL P+VLGLH S W
Sbjct: 347 LLTCTGCRGVTHYILQTFLSLAVGALTGDAVLHLTPKVLGLHTHSEEGL-----SPQPTW 401
Query: 447 KLMGLIGGIHGFFLIEKCFILLVSPNDKQGLSLVNGHVGHSHHLALNSELSDQAGRGKSA 506
+L+ ++ G++ FFL E F LL+ P D + L +G GHS H S G
Sbjct: 402 RLLAMLAGLYAFFLFENLFNLLL-PRDPEDLE--DGPCGHSSH----SHGGHSHGVSLQL 454
Query: 507 STIQLKSPE--------DSQAAEMPIGSMTASNRKCKAISLLAIMILVGDSLHNFADGLA 558
+ +L+ P+ D A E P R + LL MI +GD++HNFADGLA
Sbjct: 455 APSELRQPKPPHEGSRADLVAEESPELLNPEPRRLSPELRLLPYMITLGDAVHNFADGLA 514
Query: 559 IGAAFSSSSESGVTTTIAILCHEIPHEMGDFAVLLSSGLSMKTAILMNFISSLTAFMGLY 618
+GAAF+SS ++G+ T++A+ CHE+PHE+GDFA LL +GLS++ A+L+N S+LTAF GLY
Sbjct: 515 VGAAFASSWKTGLATSLAVFCHELPHELGDFAALLHAGLSVRQALLLNLASALTAFAGLY 574
Query: 619 IGLSVSADPCVQDWIFTVTAGMFLYLSLVEMLPEMTHVQTQRPWMMFLLQNFGLILGWLS 678
+ L+V + WI V G+FLY++L +MLP M V+ RPW++FLL N GL+ GW
Sbjct: 575 VALAVGVSEESEAWILAVATGLFLYVALCDMLPAMLKVRDPRPWLLFLLHNVGLLGGWTV 634
Query: 679 LLLLAIYEQNI 689
LLLL++YE +I
Sbjct: 635 LLLLSLYEDDI 645
>gi|115430259 solute carrier family 39 (zinc transporter), member 4
isoform 1 [Homo sapiens]
Length = 622
Score = 286 bits (731), Expect = 6e-77
Identities = 171/471 (36%), Positives = 253/471 (53%), Gaps = 32/471 (6%)
Query: 227 LPSPDYFTEYIFSSLNRTNTLRLSELDQLLNTLWTRSTCIKNEKIHQFQRKQNNIITHDQ 286
LPSP YF +++F + + L+EL L+ L + H ++ +
Sbjct: 174 LPSPQYFVDFVFQQHSSEVPMTLAELSALMQRLGV------GREAHSDHSHRHRGASSRD 227
Query: 287 DYSNFSSSMEKESEDGPVSWDQTCFSARQLVEIFLQKGLSLISKEDFKQMSPGIIQQLLS 346
SSS WD C SAR ++ + + ++ E + Q+SP ++QQ LS
Sbjct: 228 PVPLISSSNSSSV------WDTVCLSARDVMAAYGLSEQAGVTPEAWAQLSPALLQQQLS 281
Query: 347 CSCHLPKDQQAKLPPTTLEKYGYSTVAVTLLTLGSMLGTALVLFHSCEENYRLILQLFVG 406
+C + + E+Y Y ++A L+ L ++ G L+ C ILQ F+
Sbjct: 282 GACTSQSRPPVQDQLSQSERYLYGSLATLLICLCAVFGLLLLTCTGCRGVTHYILQTFLS 341
Query: 407 LAVGTLSGDALLHLIPQVLGLHKQEAPEFGHFHESKGHIWKLMGLIGGIHGFFLIEKCFI 466
LAVG L+GDA+LHL P+VLGLH S W+L+ ++ G++ FFL E F
Sbjct: 342 LAVGALTGDAVLHLTPKVLGLHTHSEEGL-----SPQPTWRLLAMLAGLYAFFLFENLFN 396
Query: 467 LLVSPNDKQGLSLVNGHVGHSHHLALNSELSDQAGRGKSASTIQLKSPE--------DSQ 518
LL+ P D + L +G GHS H S G + +L+ P+ D
Sbjct: 397 LLL-PRDPEDLE--DGPCGHSSH----SHGGHSHGVSLQLAPSELRQPKPPHEGSRADLV 449
Query: 519 AAEMPIGSMTASNRKCKAISLLAIMILVGDSLHNFADGLAIGAAFSSSSESGVTTTIAIL 578
A E P R + LL MI +GD++HNFADGLA+GAAF+SS ++G+ T++A+
Sbjct: 450 AEESPELLNPEPRRLSPELRLLPYMITLGDAVHNFADGLAVGAAFASSWKTGLATSLAVF 509
Query: 579 CHEIPHEMGDFAVLLSSGLSMKTAILMNFISSLTAFMGLYIGLSVSADPCVQDWIFTVTA 638
CHE+PHE+GDFA LL +GLS++ A+L+N S+LTAF GLY+ L+V + WI V
Sbjct: 510 CHELPHELGDFAALLHAGLSVRQALLLNLASALTAFAGLYVALAVGVSEESEAWILAVAT 569
Query: 639 GMFLYLSLVEMLPEMTHVQTQRPWMMFLLQNFGLILGWLSLLLLAIYEQNI 689
G+FLY++L +MLP M V+ RPW++FLL N GL+ GW LLLL++YE +I
Sbjct: 570 GLFLYVALCDMLPAMLKVRDPRPWLLFLLHNVGLLGGWTVLLLLSLYEDDI 620
>gi|205830424 solute carrier family 39 (zinc transporter), member 14
isoform a [Homo sapiens]
Length = 492
Score = 200 bits (509), Expect = 3e-51
Identities = 140/452 (30%), Positives = 228/452 (50%), Gaps = 73/452 (16%)
Query: 278 QNNIITHDQDYSNFSSSMEKESEDGPVSWDQTCFSARQLVEIFLQKGLSLISKEDFKQMS 337
+ N+ H Q + N S TCFS+ L S I + ++
Sbjct: 75 RGNVTQHVQGHRNLS----------------TCFSSGDLFTAHNFSEQSRIGSSELQEFC 118
Query: 338 PGIIQQLLSCSC------HLPKDQQAKLPPTTLEKYGYSTVAVTLLTLGSMLGTALVLFH 391
P I+QQL S +C + +Q + P+ +E +GY + VT+++L S+LG ++V F
Sbjct: 119 PTILQQLDSRACTSENQENEENEQTEEGRPSAVEVWGYGLLCVTVISLCSLLGASVVPFM 178
Query: 392 SCEENYRLILQLFVGLAVGTLSGDALLHLIPQVLGLHKQEAPEFGHFHESKGHIWKLMGL 451
+ Y+ +L F+ LA+GTL +AL LIP+ G + E ++ SK + +
Sbjct: 179 K-KTFYKRLLLYFIALAIGTLYSNALFQLIPEAFGFNPLE-----DYYVSKSAV-----V 227
Query: 452 IGGIHGFFLIEKCFILLVSPNDKQGLSLVNGHVGHSHHLA--LNSELSDQAGRGKS---- 505
GG + FF EK +L+ ++ H GHSH+ + L S+ + G +
Sbjct: 228 FGGFYLFFFTEKILKILLKQKNEH-------HHGHSHYASESLPSKKDQEEGVMEKLQNG 280
Query: 506 ----------ASTIQLKSP---EDSQAAEMPIGSMTASNRKC--------KAISLLAIMI 544
+S + K+P E + + + AS C I LA MI
Sbjct: 281 DLDHMIPQHCSSELDGKAPMVDEKVIVGSLSVQDLQASQSACYWLKGVRYSDIGTLAWMI 340
Query: 545 LVGDSLHNFADGLAIGAAFSSSSESGVTTTIAILCHEIPHEMGDFAVLLSSGLSMKTAIL 604
+ D LHNF DGLAIGA+F+ S G++T++AILC E PHE+GDF +LL++G+S++ A+
Sbjct: 341 TLSDGLHNFIDGLAIGASFTVSVFQGISTSVAILCEEFPHELGDFVILLNAGMSIQQALF 400
Query: 605 MNFISSLTAFMGLYIGLSVSADPCVQDWIFTVTAGMFLYLSLVEMLPEMTHV--QTQRPW 662
NF+S+ ++GL G+ ++ +WIF + GMFLY+SL +M PEM V + +R
Sbjct: 401 FNFLSACCCYLGLAFGI-LAGSHFSANWIFALAGGMFLYISLADMFPEMNEVCQEDERKG 459
Query: 663 MM---FLLQNFGLILGWLSLLLLAIYEQNIKI 691
+ F++QN GL+ G+ +++L +Y I+I
Sbjct: 460 SILIPFIIQNLGLLTGFTIMVVLTMYSGQIQI 491
>gi|190360568 solute carrier family 39 (zinc transporter), member 14
isoform a [Homo sapiens]
Length = 492
Score = 200 bits (509), Expect = 3e-51
Identities = 140/452 (30%), Positives = 228/452 (50%), Gaps = 73/452 (16%)
Query: 278 QNNIITHDQDYSNFSSSMEKESEDGPVSWDQTCFSARQLVEIFLQKGLSLISKEDFKQMS 337
+ N+ H Q + N S TCFS+ L S I + ++
Sbjct: 75 RGNVTQHVQGHRNLS----------------TCFSSGDLFTAHNFSEQSRIGSSELQEFC 118
Query: 338 PGIIQQLLSCSC------HLPKDQQAKLPPTTLEKYGYSTVAVTLLTLGSMLGTALVLFH 391
P I+QQL S +C + +Q + P+ +E +GY + VT+++L S+LG ++V F
Sbjct: 119 PTILQQLDSRACTSENQENEENEQTEEGRPSAVEVWGYGLLCVTVISLCSLLGASVVPFM 178
Query: 392 SCEENYRLILQLFVGLAVGTLSGDALLHLIPQVLGLHKQEAPEFGHFHESKGHIWKLMGL 451
+ Y+ +L F+ LA+GTL +AL LIP+ G + E ++ SK + +
Sbjct: 179 K-KTFYKRLLLYFIALAIGTLYSNALFQLIPEAFGFNPLE-----DYYVSKSAV-----V 227
Query: 452 IGGIHGFFLIEKCFILLVSPNDKQGLSLVNGHVGHSHHLA--LNSELSDQAGRGKS---- 505
GG + FF EK +L+ ++ H GHSH+ + L S+ + G +
Sbjct: 228 FGGFYLFFFTEKILKILLKQKNEH-------HHGHSHYASESLPSKKDQEEGVMEKLQNG 280
Query: 506 ----------ASTIQLKSP---EDSQAAEMPIGSMTASNRKC--------KAISLLAIMI 544
+S + K+P E + + + AS C I LA MI
Sbjct: 281 DLDHMIPQHCSSELDGKAPMVDEKVIVGSLSVQDLQASQSACYWLKGVRYSDIGTLAWMI 340
Query: 545 LVGDSLHNFADGLAIGAAFSSSSESGVTTTIAILCHEIPHEMGDFAVLLSSGLSMKTAIL 604
+ D LHNF DGLAIGA+F+ S G++T++AILC E PHE+GDF +LL++G+S++ A+
Sbjct: 341 TLSDGLHNFIDGLAIGASFTVSVFQGISTSVAILCEEFPHELGDFVILLNAGMSIQQALF 400
Query: 605 MNFISSLTAFMGLYIGLSVSADPCVQDWIFTVTAGMFLYLSLVEMLPEMTHV--QTQRPW 662
NF+S+ ++GL G+ ++ +WIF + GMFLY+SL +M PEM V + +R
Sbjct: 401 FNFLSACCCYLGLAFGI-LAGSHFSANWIFALAGGMFLYISLADMFPEMNEVCQEDERKG 459
Query: 663 MM---FLLQNFGLILGWLSLLLLAIYEQNIKI 691
+ F++QN GL+ G+ +++L +Y I+I
Sbjct: 460 SILIPFIIQNLGLLTGFTIMVVLTMYSGQIQI 491
>gi|190358541 solute carrier family 39 (zinc transporter), member 14
isoform b [Homo sapiens]
Length = 492
Score = 195 bits (495), Expect = 1e-49
Identities = 139/454 (30%), Positives = 226/454 (49%), Gaps = 77/454 (16%)
Query: 278 QNNIITHDQDYSNFSSSMEKESEDGPVSWDQTCFSARQLVEIFLQKGLSLISKEDFKQMS 337
+ N+ H Q + N S TCFS+ L S I + ++
Sbjct: 75 RGNVTQHVQGHRNLS----------------TCFSSGDLFTAHNFSEQSRIGSSELQEFC 118
Query: 338 PGIIQQLLSCSC------HLPKDQQAKLPPTTLEKYGYSTVAVTLLTLGSMLGTALVLFH 391
P I+QQL S +C + +Q + P+ +E +G+ ++V+L+ L S+LG VL
Sbjct: 119 PTILQQLDSRACTSENQENEENEQTEEGRPSAVEVWGFGFLSVSLINLASLLG---VLVL 175
Query: 392 SCEEN--YRLILQLFVGLAVGTLSGDALLHLIPQVLGLHKQEAPEFGHFHESKGHIWKLM 449
C E + +L F+ L++GTL +AL LIP+ G + E ++ SK +
Sbjct: 176 PCTEKAFFSRVLTYFIALSIGTLLSNALFQLIPEAFGFNPLE-----DYYVSKSAV---- 226
Query: 450 GLIGGIHGFFLIEKCFILLVSPNDKQGLSLVNGHVGHSHHLA--LNSELSDQAGRGKS-- 505
+ GG + FF EK +L+ ++ H GHSH+ + L S+ + G +
Sbjct: 227 -VFGGFYLFFFTEKILKILLKQKNEH-------HHGHSHYASESLPSKKDQEEGVMEKLQ 278
Query: 506 ------------ASTIQLKSP---EDSQAAEMPIGSMTASNRKC--------KAISLLAI 542
+S + K+P E + + + AS C I LA
Sbjct: 279 NGDLDHMIPQHCSSELDGKAPMVDEKVIVGSLSVQDLQASQSACYWLKGVRYSDIGTLAW 338
Query: 543 MILVGDSLHNFADGLAIGAAFSSSSESGVTTTIAILCHEIPHEMGDFAVLLSSGLSMKTA 602
MI + D LHNF DGLAIGA+F+ S G++T++AILC E PHE+GDF +LL++G+S++ A
Sbjct: 339 MITLSDGLHNFIDGLAIGASFTVSVFQGISTSVAILCEEFPHELGDFVILLNAGMSIQQA 398
Query: 603 ILMNFISSLTAFMGLYIGLSVSADPCVQDWIFTVTAGMFLYLSLVEMLPEMTHV--QTQR 660
+ NF+S+ ++GL G+ ++ +WIF + GMFLY+SL +M PEM V + +R
Sbjct: 399 LFFNFLSACCCYLGLAFGI-LAGSHFSANWIFALAGGMFLYISLADMFPEMNEVCQEDER 457
Query: 661 PWMM---FLLQNFGLILGWLSLLLLAIYEQNIKI 691
+ F++QN GL+ G+ +++L +Y I+I
Sbjct: 458 KGSILIPFIIQNLGLLTGFTIMVVLTMYSGQIQI 491
>gi|24586665 solute carrier family 39 (zinc transporter), member 8
isoform a [Homo sapiens]
Length = 460
Score = 181 bits (460), Expect = 2e-45
Identities = 131/430 (30%), Positives = 218/430 (50%), Gaps = 73/430 (16%)
Query: 300 EDGPVSWDQTCFSARQLVEIFLQKGLSLISKEDFKQMSPGIIQQLLSCSCH-LPKDQQAK 358
E G + ++Q C +A ++ + + I+ F + P ++QQL C PK K
Sbjct: 65 EPGQLHFNQ-CLTAEEIFSLHGFSNATQITSSKFSVICPAVLQQLNFHPCEDRPKH---K 120
Query: 359 LPPTTLEKYGYSTVAVTLLTLGSMLGTALVLFHSCEENY-RLILQLFVGLAVGTLSGDAL 417
P+ E +GY ++VT++ L S+LG L+L +++Y IL FVGLA+GTL +A+
Sbjct: 121 TRPSHSEVWGYGFLSVTIINLASLLG--LILTPLIKKSYFPKILTFFVGLAIGTLFSNAI 178
Query: 418 LHLIPQVLGLHKQEAPEFGHFHESKGHIWKLMGLIGGIHGFFLIEKCFILLV-------- 469
LIP+ FG + ++ K + + GG + F E+ +L+
Sbjct: 179 FQLIPEA----------FGFDPKVDSYVEKAVAVFGGFYLLFFFERMLKMLLKTYGQNGH 228
Query: 470 --------SPNDK----QGLSLVNGHVGHSH----------HLALNSELSDQAGRGKSAS 507
P +K + L +NG +++ H S +S Q G+ + +S
Sbjct: 229 THFGNDNFGPQEKTHQPKALPAINGVTCYANPAVTEANGHIHFDNVSVVSLQDGKKEPSS 288
Query: 508 TIQLKSPEDSQAAEMPIGSMTASNRKCKAISLLAIMILVGDSLHNFADGLAIGAAFSSSS 567
LK P K I +A MI + D+LHNF DGLAIGA+ + S
Sbjct: 289 CTCLKGP------------------KLSEIGTIAWMITLCDALHNFIDGLAIGASCTLSL 330
Query: 568 ESGVTTTIAILCHEIPHEMGDFAVLLSSGLSMKTAILMNFISSLTAFMGLYIGLSVSADP 627
G++T+IAILC E PHE+GDF +LL++G+S + A+L NF+S+ + ++GL G+ V +
Sbjct: 331 LQGLSTSIAILCEEFPHELGDFVILLNAGMSTRQALLFNFLSACSCYVGLAFGILV-GNN 389
Query: 628 CVQDWIFTVTAGMFLYLSLVEMLPEMTHVQTQR------PWMMFLLQNFGLILGWLSLLL 681
+ IF + GMFLY+SL +M PEM + ++ + F++QN G++ G+ ++LL
Sbjct: 390 FAPNIIFALAGGMFLYISLADMFPEMNDMLREKVTGRKTDFTFFMIQNAGMLTGFTAILL 449
Query: 682 LAIYEQNIKI 691
+ +Y I++
Sbjct: 450 ITLYAGEIEL 459
>gi|205830403 solute carrier family 39 (zinc transporter), member 8
isoform a [Homo sapiens]
Length = 460
Score = 181 bits (460), Expect = 2e-45
Identities = 131/430 (30%), Positives = 218/430 (50%), Gaps = 73/430 (16%)
Query: 300 EDGPVSWDQTCFSARQLVEIFLQKGLSLISKEDFKQMSPGIIQQLLSCSCH-LPKDQQAK 358
E G + ++Q C +A ++ + + I+ F + P ++QQL C PK K
Sbjct: 65 EPGQLHFNQ-CLTAEEIFSLHGFSNATQITSSKFSVICPAVLQQLNFHPCEDRPKH---K 120
Query: 359 LPPTTLEKYGYSTVAVTLLTLGSMLGTALVLFHSCEENY-RLILQLFVGLAVGTLSGDAL 417
P+ E +GY ++VT++ L S+LG L+L +++Y IL FVGLA+GTL +A+
Sbjct: 121 TRPSHSEVWGYGFLSVTIINLASLLG--LILTPLIKKSYFPKILTFFVGLAIGTLFSNAI 178
Query: 418 LHLIPQVLGLHKQEAPEFGHFHESKGHIWKLMGLIGGIHGFFLIEKCFILLV-------- 469
LIP+ FG + ++ K + + GG + F E+ +L+
Sbjct: 179 FQLIPEA----------FGFDPKVDSYVEKAVAVFGGFYLLFFFERMLKMLLKTYGQNGH 228
Query: 470 --------SPNDK----QGLSLVNGHVGHSH----------HLALNSELSDQAGRGKSAS 507
P +K + L +NG +++ H S +S Q G+ + +S
Sbjct: 229 THFGNDNFGPQEKTHQPKALPAINGVTCYANPAVTEANGHIHFDNVSVVSLQDGKKEPSS 288
Query: 508 TIQLKSPEDSQAAEMPIGSMTASNRKCKAISLLAIMILVGDSLHNFADGLAIGAAFSSSS 567
LK P K I +A MI + D+LHNF DGLAIGA+ + S
Sbjct: 289 CTCLKGP------------------KLSEIGTIAWMITLCDALHNFIDGLAIGASCTLSL 330
Query: 568 ESGVTTTIAILCHEIPHEMGDFAVLLSSGLSMKTAILMNFISSLTAFMGLYIGLSVSADP 627
G++T+IAILC E PHE+GDF +LL++G+S + A+L NF+S+ + ++GL G+ V +
Sbjct: 331 LQGLSTSIAILCEEFPHELGDFVILLNAGMSTRQALLFNFLSACSCYVGLAFGILV-GNN 389
Query: 628 CVQDWIFTVTAGMFLYLSLVEMLPEMTHVQTQR------PWMMFLLQNFGLILGWLSLLL 681
+ IF + GMFLY+SL +M PEM + ++ + F++QN G++ G+ ++LL
Sbjct: 390 FAPNIIFALAGGMFLYISLADMFPEMNDMLREKVTGRKTDFTFFMIQNAGMLTGFTAILL 449
Query: 682 LAIYEQNIKI 691
+ +Y I++
Sbjct: 450 ITLYAGEIEL 459
>gi|205830426 solute carrier family 39 (zinc transporter), member 14
isoform c [Homo sapiens]
Length = 481
Score = 181 bits (458), Expect = 3e-45
Identities = 135/439 (30%), Positives = 214/439 (48%), Gaps = 69/439 (15%)
Query: 278 QNNIITHDQDYSNFSSSMEKESEDGPVSWDQTCFSARQLVEIFLQKGLSLISKEDFKQMS 337
+ N+ H Q + N S TCFS+ L S I + ++
Sbjct: 75 RGNVTQHVQGHRNLS----------------TCFSSGDLFTAHNFSEQSRIGSSELQEFC 118
Query: 338 PGIIQQLLSCSC------HLPKDQQAKLPPTTLEKYGYSTVAVTLLTLGSMLGTALVLFH 391
P I+QQL S +C + +Q + P+ +E +GY + VT+++L S+LG ++V F
Sbjct: 119 PTILQQLDSRACTSENQENEENEQTEEGRPSAVEVWGYGLLCVTVISLCSLLGASVVPFM 178
Query: 392 SCEENYRLILQLFVGLAVGTLSGDALLHLIPQVLGLHKQEAPEFGHFHESKGHIWKLMGL 451
+ Y+ +L F+ LA+GTL +AL LIP+ G + E ++ SK + +
Sbjct: 179 K-KTFYKRLLLYFIALAIGTLYSNALFQLIPEAFGFNPLE-----DYYVSKSAV-----V 227
Query: 452 IGGIHGFFLIEKCFILLVSPNDKQGLSLVNGHVGHSHHLA--LNSELSDQAGRGKS---- 505
GG + FF EK +L+ ++ H GHSH+ + L S+ + G +
Sbjct: 228 FGGFYLFFFTEKILKILLKQKNEH-------HHGHSHYASESLPSKKDQEEGVMEKLQNG 280
Query: 506 ----------ASTIQLKSP---EDSQAAEMPIGSMTASNRKC--------KAISLLAIMI 544
+S + K+P E + + + AS C I LA MI
Sbjct: 281 DLDHMIPQHCSSELDGKAPMVDEKVIVGSLSVQDLQASQSACYWLKGVRYSDIGTLAWMI 340
Query: 545 LVGDSLHNFADGLAIGAAFSSSSESGVTTTIAILCHEIPHEMGDFAVLLSSGLSMKTAIL 604
+ D LHNF DGLAIGA+F+ S G++T++AILC E PHE+GDF +LL++G+S++ A+
Sbjct: 341 TLSDGLHNFIDGLAIGASFTVSVFQGISTSVAILCEEFPHELGDFVILLNAGMSIQQALF 400
Query: 605 MNFISSLTAFMGLYIGLSVSADPCVQDWIFTVTAGMFLYLSLVEMLPEMTHVQTQRPWM- 663
NF+S+ ++GL G+ ++ +WIF + GMFLY+SL +M+ + Q W
Sbjct: 401 FNFLSACCCYLGLAFGI-LAGSHFSANWIFALAGGMFLYISLADMMEFCSVAQAGVQWCH 459
Query: 664 MFLLQNFGLILGWLSLLLL 682
+ LQ L L LS L L
Sbjct: 460 LSSLQPLPLGLKRLSCLSL 478
>gi|205830407 solute carrier family 39 (zinc transporter), member 8
isoform c [Homo sapiens]
Length = 393
Score = 180 bits (456), Expect = 4e-45
Identities = 128/420 (30%), Positives = 212/420 (50%), Gaps = 72/420 (17%)
Query: 310 CFSARQLVEIFLQKGLSLISKEDFKQMSPGIIQQLLSCSCH-LPKDQQAKLPPTTLEKYG 368
C +A ++ + + I+ F + P ++QQL C PK K P+ E +G
Sbjct: 7 CLTAEEIFSLHGFSNATQITSSKFSVICPAVLQQLNFHPCEDRPKH---KTRPSHSEVWG 63
Query: 369 YSTVAVTLLTLGSMLGTALVLFHSCEENY-RLILQLFVGLAVGTLSGDALLHLIPQVLGL 427
Y ++VT++ L S+LG L+L +++Y IL FVGLA+GTL +A+ LIP+
Sbjct: 64 YGFLSVTIINLASLLG--LILTPLIKKSYFPKILTFFVGLAIGTLFSNAIFQLIPEA--- 118
Query: 428 HKQEAPEFGHFHESKGHIWKLMGLIGGIHGFFLIEKCFILLV----------------SP 471
FG + ++ K + + GG + F E+ +L+ P
Sbjct: 119 -------FGFDPKVDSYVEKAVAVFGGFYLLFFFERMLKMLLKTYGQNGHTHFGNDNFGP 171
Query: 472 NDK----QGLSLVNGHVGHSH----------HLALNSELSDQAGRGKSASTIQLKSPEDS 517
+K + L +NG +++ H S +S Q G+ + +S LK P
Sbjct: 172 QEKTHQPKALPAINGVTCYANPAVTEANGHIHFDNVSVVSLQDGKKEPSSCTCLKGP--- 228
Query: 518 QAAEMPIGSMTASNRKCKAISLLAIMILVGDSLHNFADGLAIGAAFSSSSESGVTTTIAI 577
K I +A MI + D+LHNF DGLAIGA+ + S G++T+IAI
Sbjct: 229 ---------------KLSEIGTIAWMITLCDALHNFIDGLAIGASCTLSLLQGLSTSIAI 273
Query: 578 LCHEIPHEMGDFAVLLSSGLSMKTAILMNFISSLTAFMGLYIGLSVSADPCVQDWIFTVT 637
LC E PHE+GDF +LL++G+S + A+L NF+S+ + ++GL G+ V + + IF +
Sbjct: 274 LCEEFPHELGDFVILLNAGMSTRQALLFNFLSACSCYVGLAFGILV-GNNFAPNIIFALA 332
Query: 638 AGMFLYLSLVEMLPEMTHVQTQR------PWMMFLLQNFGLILGWLSLLLLAIYEQNIKI 691
GMFLY+SL +M PEM + ++ + F++QN G++ G+ ++LL+ +Y I++
Sbjct: 333 GGMFLYISLADMFPEMNDMLREKVTGRKTDFTFFMIQNAGMLTGFTAILLITLYAGEIEL 392
>gi|206597541 solute carrier family 39 (metal ion transporter),
member 5 [Homo sapiens]
Length = 540
Score = 168 bits (425), Expect = 2e-41
Identities = 128/398 (32%), Positives = 191/398 (47%), Gaps = 34/398 (8%)
Query: 307 DQTCFSARQLVEIFLQKGLSLISKEDFKQMSPGIIQQLLSCSCHLPKDQQAKLPP-TTLE 365
++ C + QL+ F + ++ F + P ++ Q+ S C A PP L
Sbjct: 155 NEDCLNGSQLLVNFGLSPAAPLTPRQFALLCPALLYQIDSRVCI---GAPAPAPPGDLLS 211
Query: 366 KYGYSTVAVTLLTLGSMLGTALVLFHSCEENYRLILQLFVGLAVGTLSGDALLHLIPQVL 425
S +AV LL+L S L L+ R +L LAVGTL GDALLHL+P
Sbjct: 212 ALLQSALAVLLLSLPSPLSLLLLRLLG-PRLLRPLLGFLGALAVGTLCGDALLHLLP--- 267
Query: 426 GLHKQEAPEFGHFHESKGHIWKLMGLIGGIHGFFLIEKCFILL----VSPN--------- 472
H QE G + + + ++GG+ F++E LL + P
Sbjct: 268 --HAQEGRHAGPGGLPEKDLGPGLSVLGGLFLLFVLENMLGLLRHRGLRPRCCRRKRRNL 325
Query: 473 DKQGLSLVNGHVGHSHHLALNSELSDQAGRGKSASTIQLKSPEDSQAAEMPIGSMTASNR 532
+ + L NG L E Q R K++ +P Q G ++
Sbjct: 326 ETRNLDPENGSGMALQPLQAAPEPGAQGQREKNSQHPPALAPPGHQGHSH--GHQGGTD- 382
Query: 533 KCKAISLLAIMILVGDSLHNFADGLAIGAAFSSSSESGVTTTIAILCHEIPHEMGDFAVL 592
+ M+L+GD LHN DGLAIGAAFS SG++TT+A+ CHE+PHE+GDFA+L
Sbjct: 383 -------ITWMVLLGDGLHNLTDGLAIGAAFSDGFSSGLSTTLAVFCHELPHELGDFAML 435
Query: 593 LSSGLSMKTAILMNFISSLTAFMGLYIGLSVSADPC-VQDWIFTVTAGMFLYLSLVEMLP 651
L SGLS + +L++ +S G +G+ +S P + W+F VTAG+FLY++LV+MLP
Sbjct: 436 LQSGLSFRRLLLLSLVSGALGLGGAVLGVGLSLGPVPLTPWVFGVTAGVFLYVALVDMLP 495
Query: 652 EMTHVQTQRPWMMFLLQNFGLILGWLSLLLLAIYEQNI 689
+ P LLQ GL+LG +L + + E+ +
Sbjct: 496 ALLRPPEPLPTPHVLLQGLGLLLGGGLMLAITLLEERL 533
>gi|206597539 solute carrier family 39 (metal ion transporter),
member 5 [Homo sapiens]
Length = 540
Score = 168 bits (425), Expect = 2e-41
Identities = 128/398 (32%), Positives = 191/398 (47%), Gaps = 34/398 (8%)
Query: 307 DQTCFSARQLVEIFLQKGLSLISKEDFKQMSPGIIQQLLSCSCHLPKDQQAKLPP-TTLE 365
++ C + QL+ F + ++ F + P ++ Q+ S C A PP L
Sbjct: 155 NEDCLNGSQLLVNFGLSPAAPLTPRQFALLCPALLYQIDSRVCI---GAPAPAPPGDLLS 211
Query: 366 KYGYSTVAVTLLTLGSMLGTALVLFHSCEENYRLILQLFVGLAVGTLSGDALLHLIPQVL 425
S +AV LL+L S L L+ R +L LAVGTL GDALLHL+P
Sbjct: 212 ALLQSALAVLLLSLPSPLSLLLLRLLG-PRLLRPLLGFLGALAVGTLCGDALLHLLP--- 267
Query: 426 GLHKQEAPEFGHFHESKGHIWKLMGLIGGIHGFFLIEKCFILL----VSPN--------- 472
H QE G + + + ++GG+ F++E LL + P
Sbjct: 268 --HAQEGRHAGPGGLPEKDLGPGLSVLGGLFLLFVLENMLGLLRHRGLRPRCCRRKRRNL 325
Query: 473 DKQGLSLVNGHVGHSHHLALNSELSDQAGRGKSASTIQLKSPEDSQAAEMPIGSMTASNR 532
+ + L NG L E Q R K++ +P Q G ++
Sbjct: 326 ETRNLDPENGSGMALQPLQAAPEPGAQGQREKNSQHPPALAPPGHQGHSH--GHQGGTD- 382
Query: 533 KCKAISLLAIMILVGDSLHNFADGLAIGAAFSSSSESGVTTTIAILCHEIPHEMGDFAVL 592
+ M+L+GD LHN DGLAIGAAFS SG++TT+A+ CHE+PHE+GDFA+L
Sbjct: 383 -------ITWMVLLGDGLHNLTDGLAIGAAFSDGFSSGLSTTLAVFCHELPHELGDFAML 435
Query: 593 LSSGLSMKTAILMNFISSLTAFMGLYIGLSVSADPC-VQDWIFTVTAGMFLYLSLVEMLP 651
L SGLS + +L++ +S G +G+ +S P + W+F VTAG+FLY++LV+MLP
Sbjct: 436 LQSGLSFRRLLLLSLVSGALGLGGAVLGVGLSLGPVPLTPWVFGVTAGVFLYVALVDMLP 495
Query: 652 EMTHVQTQRPWMMFLLQNFGLILGWLSLLLLAIYEQNI 689
+ P LLQ GL+LG +L + + E+ +
Sbjct: 496 ALLRPPEPLPTPHVLLQGLGLLLGGGLMLAITLLEERL 533
>gi|205830405 solute carrier family 39 (zinc transporter), member 8
isoform b [Homo sapiens]
Length = 444
Score = 165 bits (418), Expect = 1e-40
Identities = 122/393 (31%), Positives = 197/393 (50%), Gaps = 67/393 (17%)
Query: 300 EDGPVSWDQTCFSARQLVEIFLQKGLSLISKEDFKQMSPGIIQQLLSCSCH-LPKDQQAK 358
E G + ++Q C +A ++ + + I+ F + P ++QQL C PK K
Sbjct: 65 EPGQLHFNQ-CLTAEEIFSLHGFSNATQITSSKFSVICPAVLQQLNFHPCEDRPKH---K 120
Query: 359 LPPTTLEKYGYSTVAVTLLTLGSMLGTALVLFHSCEENY-RLILQLFVGLAVGTLSGDAL 417
P+ E +GY ++VT++ L S+LG L+L +++Y IL FVGLA+GTL +A+
Sbjct: 121 TRPSHSEVWGYGFLSVTIINLASLLG--LILTPLIKKSYFPKILTFFVGLAIGTLFSNAI 178
Query: 418 LHLIPQVLGLHKQEAPEFGHFHESKGHIWKLMGLIGGIHGFFLIEKCFILLV-------- 469
LIP+ FG + ++ K + + GG + F E+ +L+
Sbjct: 179 FQLIPEA----------FGFDPKVDSYVEKAVAVFGGFYLLFFFERMLKMLLKTYGQNGH 228
Query: 470 --------SPNDK----QGLSLVNGHVGHSH----------HLALNSELSDQAGRGKSAS 507
P +K + L +NG +++ H S +S Q G+ + +S
Sbjct: 229 THFGNDNFGPQEKTHQPKALPAINGVTCYANPAVTEANGHIHFDNVSVVSLQDGKKEPSS 288
Query: 508 TIQLKSPEDSQAAEMPIGSMTASNRKCKAISLLAIMILVGDSLHNFADGLAIGAAFSSSS 567
LK P K I +A MI + D+LHNF DGLAIGA+ + S
Sbjct: 289 CTCLKGP------------------KLSEIGTIAWMITLCDALHNFIDGLAIGASCTLSL 330
Query: 568 ESGVTTTIAILCHEIPHEMGDFAVLLSSGLSMKTAILMNFISSLTAFMGLYIGLSVSADP 627
G++T+IAILC E PHE+GDF +LL++G+S + A+L NF+S+ + ++GL G+ V +
Sbjct: 331 LQGLSTSIAILCEEFPHELGDFVILLNAGMSTRQALLFNFLSACSCYVGLAFGILV-GNN 389
Query: 628 CVQDWIFTVTAGMFLYLSLVEMLPEMTHVQTQR 660
+ IF + GMFLY+SL +M PEM + ++
Sbjct: 390 FAPNIIFALAGGMFLYISLADMFPEMNDMLREK 422
>gi|187936949 solute carrier family 39 (zinc transporter), member 10
[Homo sapiens]
Length = 831
Score = 161 bits (408), Expect = 2e-39
Identities = 80/169 (47%), Positives = 119/169 (70%), Gaps = 7/169 (4%)
Query: 528 TASNRKCKAISLLAIMILVGDSLHNFADGLAIGAAFSSSSESGVTTTIAILCHEIPHEMG 587
+ S+ K I+ +A M+++GD +HNF+DGLAIGAAFS+ G++T+IA+ CHE+PHE+G
Sbjct: 657 SGSDLKETGIANIAWMVIMGDGIHNFSDGLAIGAAFSAGLTGGISTSIAVFCHELPHELG 716
Query: 588 DFAVLLSSGLSMKTAILMNFISSLTAFMGLYIGLSVSA-DPCVQDWIFTVTAGMFLYLSL 646
DFAVLL +G+++K AI+ N +S++ A++G+ IG +V + WIF VTAGMFLY++L
Sbjct: 717 DFAVLLKAGMTVKQAIVYNLLSAMMAYIGMLIGTAVGQYANNITLWIFAVTAGMFLYVAL 776
Query: 647 VEMLPEMTHVQTQR------PWMMFLLQNFGLILGWLSLLLLAIYEQNI 689
V+MLPEM H P F+LQN GL+ G+ +L++A+YE I
Sbjct: 777 VDMLPEMLHGDGDNEEHGFCPVGQFILQNLGLLFGFAIMLVIALYEDKI 825
Score = 69.3 bits (168), Expect = 1e-11
Identities = 58/193 (30%), Positives = 90/193 (46%), Gaps = 29/193 (15%)
Query: 310 CFSARQLVEIFLQKGLSLISKEDFKQMSPGIIQQLLSCSC--HLPK------DQQAKLPP 361
C + QL++ + S IS + F + P ++ Q+ S C H K ++ L P
Sbjct: 337 CLNVTQLLKYYGHGANSPISTDLFTYLCPALLYQIDSRLCIEHFDKLLVEDINKDKNLVP 396
Query: 362 TTLEKYGYST-----VAVTLLTLGSMLGTALV--LFHSCEENYRLILQLFVGLAVGTLSG 414
G S +++T+++L S+LG LV + C ++ +L V LAVGT+SG
Sbjct: 397 EDEANIGASAWICGIISITVISLLSLLGVILVPIINQGC---FKFLLTFLVALAVGTMSG 453
Query: 415 DALLHLIPQVLGLH---KQEAPEFGHFH--------ESKGHIWKLMGLIGGIHGFFLIEK 463
DALLHL+P G H Q A GH H E + K + +GGI+ F+IE
Sbjct: 454 DALLHLLPHSQGGHDHSHQHAHGHGHSHGHESNKFLEEYDAVLKGLVALGGIYLLFIIEH 513
Query: 464 CFILLVSPNDKQG 476
C + ++G
Sbjct: 514 CIRMFKHYKQQRG 526
>gi|55741750 solute carrier family 39 (zinc transporter), member 10
[Homo sapiens]
Length = 831
Score = 161 bits (408), Expect = 2e-39
Identities = 80/169 (47%), Positives = 119/169 (70%), Gaps = 7/169 (4%)
Query: 528 TASNRKCKAISLLAIMILVGDSLHNFADGLAIGAAFSSSSESGVTTTIAILCHEIPHEMG 587
+ S+ K I+ +A M+++GD +HNF+DGLAIGAAFS+ G++T+IA+ CHE+PHE+G
Sbjct: 657 SGSDLKETGIANIAWMVIMGDGIHNFSDGLAIGAAFSAGLTGGISTSIAVFCHELPHELG 716
Query: 588 DFAVLLSSGLSMKTAILMNFISSLTAFMGLYIGLSVSA-DPCVQDWIFTVTAGMFLYLSL 646
DFAVLL +G+++K AI+ N +S++ A++G+ IG +V + WIF VTAGMFLY++L
Sbjct: 717 DFAVLLKAGMTVKQAIVYNLLSAMMAYIGMLIGTAVGQYANNITLWIFAVTAGMFLYVAL 776
Query: 647 VEMLPEMTHVQTQR------PWMMFLLQNFGLILGWLSLLLLAIYEQNI 689
V+MLPEM H P F+LQN GL+ G+ +L++A+YE I
Sbjct: 777 VDMLPEMLHGDGDNEEHGFCPVGQFILQNLGLLFGFAIMLVIALYEDKI 825
Score = 69.3 bits (168), Expect = 1e-11
Identities = 58/193 (30%), Positives = 90/193 (46%), Gaps = 29/193 (15%)
Query: 310 CFSARQLVEIFLQKGLSLISKEDFKQMSPGIIQQLLSCSC--HLPK------DQQAKLPP 361
C + QL++ + S IS + F + P ++ Q+ S C H K ++ L P
Sbjct: 337 CLNVTQLLKYYGHGANSPISTDLFTYLCPALLYQIDSRLCIEHFDKLLVEDINKDKNLVP 396
Query: 362 TTLEKYGYST-----VAVTLLTLGSMLGTALV--LFHSCEENYRLILQLFVGLAVGTLSG 414
G S +++T+++L S+LG LV + C ++ +L V LAVGT+SG
Sbjct: 397 EDEANIGASAWICGIISITVISLLSLLGVILVPIINQGC---FKFLLTFLVALAVGTMSG 453
Query: 415 DALLHLIPQVLGLH---KQEAPEFGHFH--------ESKGHIWKLMGLIGGIHGFFLIEK 463
DALLHL+P G H Q A GH H E + K + +GGI+ F+IE
Sbjct: 454 DALLHLLPHSQGGHDHSHQHAHGHGHSHGHESNKFLEEYDAVLKGLVALGGIYLLFIIEH 513
Query: 464 CFILLVSPNDKQG 476
C + ++G
Sbjct: 514 CIRMFKHYKQQRG 526
>gi|153252201 solute carrier family 39 (zinc transporter), member 6
isoform 1 [Homo sapiens]
Length = 755
Score = 156 bits (394), Expect = 7e-38
Identities = 74/162 (45%), Positives = 115/162 (70%), Gaps = 5/162 (3%)
Query: 533 KCKAISLLAIMILVGDSLHNFADGLAIGAAFSSSSESGVTTTIAILCHEIPHEMGDFAVL 592
K ++ LA M+++GD LHNF+DGLAIGAAF+ SG++T++A+ CHE+PHE+GDFAVL
Sbjct: 588 KDAGVATLAWMVIMGDGLHNFSDGLAIGAAFTEGLSSGLSTSVAVFCHELPHELGDFAVL 647
Query: 593 LSSGLSMKTAILMNFISSLTAFMGLYIGLSVS-ADPCVQDWIFTVTAGMFLYLSLVEMLP 651
L +G+++K A+L N +S++ A++G+ G+ + V WIF +TAG+F+Y++LV+M+P
Sbjct: 648 LKAGMTVKQAVLYNALSAMLAYLGMATGIFIGHYAENVSMWIFALTAGLFMYVALVDMVP 707
Query: 652 EMTHVQTQ----RPWMMFLLQNFGLILGWLSLLLLAIYEQNI 689
EM H W F LQN G++LG+ +LL++I+E I
Sbjct: 708 EMLHNDASDHGCSRWGYFFLQNAGMLLGFGIMLLISIFEHKI 749
Score = 69.3 bits (168), Expect = 1e-11
Identities = 53/194 (27%), Positives = 91/194 (46%), Gaps = 30/194 (15%)
Query: 308 QTCFSARQLVEIFLQKGLSL---ISKEDFKQMSPGIIQQLLSCSCHL-PKDQQAKLPPTT 363
Q CF+A +L+ G+ + ++ +F + P II Q+ + SC + +++A++PP T
Sbjct: 262 QECFNASKLLT---SHGMGIQVPLNATEFNYLCPAIINQIDARSCLIHTSEKKAEIPPKT 318
Query: 364 LE---KYGYSTVAVTLLTLGSMLGTALVLFHSCEENYRLILQLFVGLAVGTLSGDALLHL 420
+ +A+++++ S+LG LV + ++ +L V LAVGTLSGDA LHL
Sbjct: 319 YSLQIAWVGGFIAISIISFLSLLGVILVPLMN-RVFFKFLLSFLVALAVGTLSGDAFLHL 377
Query: 421 IPQVLGLH------------KQEAPEFGHFHESK-------GHIWKLMGLIGGIHGFFLI 461
+P H + P F H WK + +GG++ FL+
Sbjct: 378 LPHSHASHHHSHSHEEPAMEMKRGPLFSHLSSQNIEESAYFDSTWKGLTALGGLYFMFLV 437
Query: 462 EKCFILLVSPNDKQ 475
E L+ DK+
Sbjct: 438 EHVLTLIKQFKDKK 451
>gi|117553619 solute carrier family 39, member 7 [Homo sapiens]
Length = 469
Score = 140 bits (352), Expect = 5e-33
Identities = 103/350 (29%), Positives = 158/350 (45%), Gaps = 45/350 (12%)
Query: 367 YGYSTVAVTLLTLGSMLGTALVLFHSCEENYRLILQLFVGLAVGTLSGDALLHLIPQVLG 426
+ Y+ A L++ L+ S +R +LQ+ + A G L GDA LHLIP L
Sbjct: 135 WAYALGATVLISAAPFFVLFLIPVESNSPRHRSLLQILLSFASGGLLGDAFLHLIPHALE 194
Query: 427 LHKQ---EAPEFGHFHESKGHIWKL-MGLIGGIHGFFLIEKCFILLVSPNDKQGLSLVNG 482
H E P GH H +G I + + ++ GI F ++EK + V G
Sbjct: 195 PHSHHTLEQPGHGHSHSGQGPILSVGLWVLSGIVAFLVVEKF------------VRHVKG 242
Query: 483 HVGHSH-HLALNSELSDQAGRGKSASTIQLKSPEDSQAAEM----------------PIG 525
GHSH H +S G G+ + + K + + E P+
Sbjct: 243 GHGHSHGHGHAHSHTRGSHGHGRQERSTKEKQSSEEEEKETRGVQKRRGGSTVPKDGPVR 302
Query: 526 SMTASNRKCKA-ISLLAIMILVGDSLHNFADGLAIGAAFSSSSESGVTTTIAILCHEIPH 584
A K + + + L D HNF DGLAIGA+F G+ TT+ +L HE+PH
Sbjct: 303 PQNAEEEKRGLDLRVSGYLNLAADLAHNFTDGLAIGASFRGGRGLGILTTMTVLLHEVPH 362
Query: 585 EMGDFAVLLSSGLSMKTAILMNFISSLTAFMGLYIGL--------SVSADPCVQDWIFTV 636
E+GDFA+L+ SG S K A+ + ++++ A G L S A W+
Sbjct: 363 EVGDFAILVQSGCSKKQAMRLQLLTAVGALAGTACALLTEGGAVGSEIAGGAGPGWVLPF 422
Query: 637 TAGMFLYLSLVEMLPEMTHVQTQRPWMMFLLQNFGLILGWLSLLLLAIYE 686
TAG F+Y++ V +LPE+ + + LL+ GL+ G + ++L+A E
Sbjct: 423 TAGGFIYVATVSVLPELLREASP---LQSLLEVLGLLGGVIMMVLIAHLE 469
>gi|117553608 solute carrier family 39, member 7 [Homo sapiens]
Length = 469
Score = 140 bits (352), Expect = 5e-33
Identities = 103/350 (29%), Positives = 158/350 (45%), Gaps = 45/350 (12%)
Query: 367 YGYSTVAVTLLTLGSMLGTALVLFHSCEENYRLILQLFVGLAVGTLSGDALLHLIPQVLG 426
+ Y+ A L++ L+ S +R +LQ+ + A G L GDA LHLIP L
Sbjct: 135 WAYALGATVLISAAPFFVLFLIPVESNSPRHRSLLQILLSFASGGLLGDAFLHLIPHALE 194
Query: 427 LHKQ---EAPEFGHFHESKGHIWKL-MGLIGGIHGFFLIEKCFILLVSPNDKQGLSLVNG 482
H E P GH H +G I + + ++ GI F ++EK + V G
Sbjct: 195 PHSHHTLEQPGHGHSHSGQGPILSVGLWVLSGIVAFLVVEKF------------VRHVKG 242
Query: 483 HVGHSH-HLALNSELSDQAGRGKSASTIQLKSPEDSQAAEM----------------PIG 525
GHSH H +S G G+ + + K + + E P+
Sbjct: 243 GHGHSHGHGHAHSHTRGSHGHGRQERSTKEKQSSEEEEKETRGVQKRRGGSTVPKDGPVR 302
Query: 526 SMTASNRKCKA-ISLLAIMILVGDSLHNFADGLAIGAAFSSSSESGVTTTIAILCHEIPH 584
A K + + + L D HNF DGLAIGA+F G+ TT+ +L HE+PH
Sbjct: 303 PQNAEEEKRGLDLRVSGYLNLAADLAHNFTDGLAIGASFRGGRGLGILTTMTVLLHEVPH 362
Query: 585 EMGDFAVLLSSGLSMKTAILMNFISSLTAFMGLYIGL--------SVSADPCVQDWIFTV 636
E+GDFA+L+ SG S K A+ + ++++ A G L S A W+
Sbjct: 363 EVGDFAILVQSGCSKKQAMRLQLLTAVGALAGTACALLTEGGAVGSEIAGGAGPGWVLPF 422
Query: 637 TAGMFLYLSLVEMLPEMTHVQTQRPWMMFLLQNFGLILGWLSLLLLAIYE 686
TAG F+Y++ V +LPE+ + + LL+ GL+ G + ++L+A E
Sbjct: 423 TAGGFIYVATVSVLPELLREASP---LQSLLEVLGLLGGVIMMVLIAHLE 469
>gi|153252214 solute carrier family 39 (zinc transporter), member 6
isoform 2 [Homo sapiens]
Length = 433
Score = 128 bits (321), Expect = 2e-29
Identities = 57/119 (47%), Positives = 91/119 (76%), Gaps = 1/119 (0%)
Query: 533 KCKAISLLAIMILVGDSLHNFADGLAIGAAFSSSSESGVTTTIAILCHEIPHEMGDFAVL 592
K ++ LA M+++GD LHNF+DGLAIGAAF+ SG++T++A+ CHE+PHE+GDFAVL
Sbjct: 313 KDAGVATLAWMVIMGDGLHNFSDGLAIGAAFTEGLSSGLSTSVAVFCHELPHELGDFAVL 372
Query: 593 LSSGLSMKTAILMNFISSLTAFMGLYIGLSVS-ADPCVQDWIFTVTAGMFLYLSLVEML 650
L +G+++K A+L N +S++ A++G+ G+ + V WIF +TAG+F+Y++LV+M+
Sbjct: 373 LKAGMTVKQAVLYNALSAMLAYLGMATGIFIGHYAENVSMWIFALTAGLFMYVALVDMV 431
Score = 65.9 bits (159), Expect = 1e-10
Identities = 47/171 (27%), Positives = 80/171 (46%), Gaps = 24/171 (14%)
Query: 328 ISKEDFKQMSPGIIQQLLSCSCHL-PKDQQAKLPPTTLE---KYGYSTVAVTLLTLGSML 383
++ +F + P II Q+ + SC + +++A++PP T + +A+++++ S+L
Sbjct: 7 LNATEFNYLCPAIINQIDARSCLIHTSEKKAEIPPKTYSLQIAWVGGFIAISIISFLSLL 66
Query: 384 GTALVLFHSCEENYRLILQLFVGLAVGTLSGDALLHLIPQVLGLH------------KQE 431
G LV + ++ +L V LAVGTLSGDA LHL+P H +
Sbjct: 67 GVILVPLMN-RVFFKFLLSFLVALAVGTLSGDAFLHLLPHSHASHHHSHSHEEPAMEMKR 125
Query: 432 APEFGHFHESK-------GHIWKLMGLIGGIHGFFLIEKCFILLVSPNDKQ 475
P F H WK + +GG++ FL+E L+ DK+
Sbjct: 126 GPLFSHLSSQNIEESAYFDSTWKGLTALGGLYFMFLVEHVLTLIKQFKDKK 176
>gi|40255101 solute carrier family 39 (zinc transporter), member 13
isoform b [Homo sapiens]
Length = 364
Score = 99.8 bits (247), Expect = 8e-21
Identities = 83/289 (28%), Positives = 142/289 (49%), Gaps = 36/289 (12%)
Query: 401 LQLFVGLAVGTLSGDALLHLIPQVLGLHKQEAPEFGHFHESKGHIWKL-MGLIGGIHGFF 459
L+ + A+G L G+ LHL+P+ +P G +S +L + +I GI F
Sbjct: 106 LKQLLSFALGGLLGNVFLHLLPEAWAYTCSASP--GGEGQSLQQQQQLGLWVIAGILTFL 163
Query: 460 LIEKCFILLVSPNDKQGLSLVNGHVGHSHHLALNSELSDQAGRGKSASTIQLKSPEDSQA 519
+EK F+ + ++G S + ALN L P A
Sbjct: 164 ALEKMFL----DSKEEGTSQAPNKDPTAAAAALNGGHC-------------LAQP----A 202
Query: 520 AEMPIGSMTASNRKCKAISLLAIMILVGDSLHNFADGLAIGAAFSSSSESGVTTTIAILC 579
AE +G++ S + ++LLA +++ NF GLA+ A+F S + G+ TT+AIL
Sbjct: 203 AEPGLGAVVRSIKVSGYLNLLA------NTIDNFTHGLAVAASFLVSKKIGLLTTMAILL 256
Query: 580 HEIPHEMGDFAVLLSSGLSMKTAILMNFISSLTAFMGLYIGLSVSADPCVQD---WIFTV 636
HEIPHE+GDFA+LL +G +A + ++L +G + + V++ W+
Sbjct: 257 HEIPHEVGDFAILLRAGFDRWSAAKLQLSTALGGLLGAGFAICTQSPKGVEETAAWVLPF 316
Query: 637 TAGMFLYLSLVEMLPEMTHVQTQRPWMMFLLQNFGLILGWLSLLLLAIY 685
T+G FLY++LV +LP++ ++ + PW L Q L G + ++L +++
Sbjct: 317 TSGGFLYIALVNVLPDL--LEEEDPWRS-LQQLLLLCAGIVVMVLFSLF 362
>gi|190014617 solute carrier family 39 (zinc transporter), member 13
isoform a [Homo sapiens]
Length = 371
Score = 97.1 bits (240), Expect = 5e-20
Identities = 84/296 (28%), Positives = 142/296 (47%), Gaps = 43/296 (14%)
Query: 401 LQLFVGLAVGTLSGDALLHLIPQVLGLHKQEAPEFGHFHESKGHIWKL-MGLIGGIHGFF 459
L+ + A+G L G+ LHL+P+ +P G +S +L + +I GI F
Sbjct: 106 LKQLLSFALGGLLGNVFLHLLPEAWAYTCSASP--GGEGQSLQQQQQLGLWVIAGILTFL 163
Query: 460 LIEKCFILLVSPNDKQGLSLVNGHVGHSHHLALNSELSDQAGRGKSASTIQLKSPEDSQA 519
+EK F+ + ++G S + ALN L P A
Sbjct: 164 ALEKMFL----DSKEEGTSQAPNKDPTAAAAALNGGHC-------------LAQP----A 202
Query: 520 AEMPIGSMTASNRKCKAISLLAIMILVGDSLHNFADGLAIGAAFSSSSESGVTTTIAILC 579
AE +G++ S + ++LLA +++ NF GLA+ A+F S + G+ TT+AIL
Sbjct: 203 AEPGLGAVVRSIKVSGYLNLLA------NTIDNFTHGLAVAASFLVSKKIGLLTTMAILL 256
Query: 580 HEIPHEMGDFAVLLSSGLSMKTAILMNFISSLTAFMGLYIGLS-------VSADPCVQD- 631
HEIPHE+GDFA+LL +G +A + ++L +G + V P ++
Sbjct: 257 HEIPHEVGDFAILLRAGFDRWSAAKLQLSTALGGLLGAGFAICTQSPKGVVGCSPAAEET 316
Query: 632 --WIFTVTAGMFLYLSLVEMLPEMTHVQTQRPWMMFLLQNFGLILGWLSLLLLAIY 685
W+ T+G FLY++LV +LP++ ++ + PW L Q L G + ++L +++
Sbjct: 317 AAWVLPFTSGGFLYIALVNVLPDL--LEEEDPWRS-LQQLLLLCAGIVVMVLFSLF 369
>gi|40254928 solute carrier family 39 (zinc transporter), member 9
[Homo sapiens]
Length = 307
Score = 58.5 bits (140), Expect = 2e-08
Identities = 85/347 (24%), Positives = 147/347 (42%), Gaps = 74/347 (21%)
Query: 372 VAVTLLTLGSMLGTALVLFHSCEENY-RLILQLFVGLAVGTLSGDALLHLIPQVLGLHKQ 430
++++LL+L ++G + N+ L+L L G L G AL ++P+ + +
Sbjct: 5 ISISLLSLAMLVGCYVAGIIPLAVNFSEERLKLVTVLGAGLLCGTALAVIVPEGVHALYE 64
Query: 431 EAPEFGHFHESKGHIWKLMGLIGGIHGFFLIEKCFILLVSPNDKQGLSLVNGHVGHSH-H 489
+ E H S+ H V +DK V HSH H
Sbjct: 65 DILEGKHHQASETHN-----------------------VIASDKAAEKSVVHEHEHSHDH 101
Query: 490 LALNSELS-------------DQAGRGKSASTIQLKSPEDSQAAEMPIGSMTASNRKCKA 536
L++ + DQ G ST +D +AA +SN K
Sbjct: 102 TQLHAYIGVSLVLGFVFMLLVDQIGNSHVHST------DDPEAAR-------SSNSK--- 145
Query: 537 ISLLAIMILVGDSLHNFADGLAIGAAFSSSSES-GVTTTIAILCHEIPHEMGDFAVLLSS 595
I +G +H ADG+A+GAA S+S S + +AI+ H+ P G + L+ +
Sbjct: 146 -----ITTTLGLVVHAAADGVALGAAASTSQTSVQLIVFVAIMLHKAPAAFGLVSFLMHA 200
Query: 596 GLS---MKTAILMNFISSLTAFMGLYIGLSVSADPCVQDWIFT-----VTAGMFLYLSLV 647
GL ++ +L+ +++ M Y+GLS S+ + + T +AG FLY++ V
Sbjct: 201 GLERNRIRKHLLVFALAAPVMSMVTYLGLSKSSKEALSEVNATGVAMLFSAGTFLYVATV 260
Query: 648 EMLPEMTHV-QTQRPWM-----MFLLQNFGLILGWLSLLLLAIYEQN 688
+LPE+ + + +P + L+ L+LG L L+L++ Q+
Sbjct: 261 HVLPEVGGIGHSHKPDATGGRGLSRLEVAALVLGCLIPLILSVGHQH 307
>gi|156415986 solute carrier family 39 (zinc transporter), member 2
[Homo sapiens]
Length = 309
Score = 45.8 bits (107), Expect = 1e-04
Identities = 34/119 (28%), Positives = 61/119 (51%), Gaps = 8/119 (6%)
Query: 539 LLAIMILVGDSLHNFADGLAIGAAFSSSSESGVTTTIAILCHEIPHEMGDFAVLLSSGLS 598
L A+++L+ S H+ +GLA+G + + V +A+L H+ G L+ G S
Sbjct: 163 LRALVLLLSLSFHSVFEGLAVG--LQPTVAATVQLCLAVLAHKGLVVFGVGMRLVHLGTS 220
Query: 599 MKTAILMNFISSLTAFMGLYIGLSVSADPC------VQDWIFTVTAGMFLYLSLVEMLP 651
+ A+ + +L + +GL +GL+V+ Q + V AG FLY++ +E+LP
Sbjct: 221 SRWAVFSILLLALMSPLGLAVGLAVTGGDSEGGRGLAQAVLEGVAAGTFLYVTFLEILP 279
>gi|21361423 solute carrier family 39 (zinc transporter), member 1
[Homo sapiens]
Length = 324
Score = 41.6 bits (96), Expect = 0.002
Identities = 42/159 (26%), Positives = 71/159 (44%), Gaps = 8/159 (5%)
Query: 525 GSMTASNRKCKAISLLAIMILVGDSLHNFADGLAIGAAFSSSSESGVTTTIAILCHEIPH 584
G AS +L A +++ +LH+ +GLA+G + +A+L H+
Sbjct: 164 GVPQASGAPATPSALRACVLVFSLALHSVFEGLAVG--LQRDRARAMELCLALLLHKGIL 221
Query: 585 EMGDFAVLLSSGLSMKTAILMNFISSLTAFMGLYIG--LSVSADPC---VQDWIFTVTAG 639
+ LL S L + + S +G+ +G L+ SA P Q + + AG
Sbjct: 222 AVSLSLRLLQSHLRAQVVAGCGILFSCMTPLGIGLGAALAESAGPLHQLAQSVLEGMAAG 281
Query: 640 MFLYLSLVEMLPEMTHVQTQRPW-MMFLLQNFGLILGWL 677
FLY++ +E+LP+ QR ++ LL F L+ G L
Sbjct: 282 TFLYITFLEILPQELASSEQRILKVILLLAGFALLTGLL 320
>gi|229577422 solute carrier family 39, member 11 isoform 1 [Homo
sapiens]
Length = 342
Score = 37.4 bits (85), Expect = 0.047
Identities = 40/177 (22%), Positives = 72/177 (40%), Gaps = 14/177 (7%)
Query: 484 VGHSHHLALNSELSDQAGRGKSASTIQLKSPEDSQAAEMPIGSMTASNRKCKAISLLAIM 543
+G + L+ SE + R K+A+T + P + + S+ + A+ +LAI
Sbjct: 143 IGRAGLLSDKSENGEAYQRKKAAATGLPEGPAVPVPSRGNLAQPGGSSWRRIALLILAIT 202
Query: 544 ILVGDSLHNFADGLAIGAAF-------SSSSESGVTTTIAILCHEIPHEMGDFAVLLSSG 596
I HN +GLA+G F S++ ES I I P + L +G
Sbjct: 203 I------HNVPEGLAVGVGFGAIEKTASATFESARNLAIGIGIQNFPEGLAVSLPLRGAG 256
Query: 597 LSMKTAILMNFISSLT-AFMGLYIGLSVSADPCVQDWIFTVTAGMFLYLSLVEMLPE 652
S A +S + G++ +V + + AG +Y+ + +++PE
Sbjct: 257 FSTWRAFWYGQLSGMVEPLAGVFGAFAVVLAEPILPYALAFAAGAMVYVVMDDIIPE 313
>gi|229577418 solute carrier family 39, member 11 isoform 2 [Homo
sapiens]
Length = 335
Score = 35.0 bits (79), Expect = 0.23
Identities = 38/167 (22%), Positives = 67/167 (40%), Gaps = 14/167 (8%)
Query: 494 SELSDQAGRGKSASTIQLKSPEDSQAAEMPIGSMTASNRKCKAISLLAIMILVGDSLHNF 553
SE + R K+A+T + P + + S+ + A+ +LAI I HN
Sbjct: 146 SENGEAYQRKKAAATGLPEGPAVPVPSRGNLAQPGGSSWRRIALLILAITI------HNV 199
Query: 554 ADGLAIGAAF-------SSSSESGVTTTIAILCHEIPHEMGDFAVLLSSGLSMKTAILMN 606
+GLA+G F S++ ES I I P + L +G S A
Sbjct: 200 PEGLAVGVGFGAIEKTASATFESARNLAIGIGIQNFPEGLAVSLPLRGAGFSTWRAFWYG 259
Query: 607 FISSLT-AFMGLYIGLSVSADPCVQDWIFTVTAGMFLYLSLVEMLPE 652
+S + G++ +V + + AG +Y+ + +++PE
Sbjct: 260 QLSGMVEPLAGVFGAFAVVLAEPILPYALAFAAGAMVYVVMDDIIPE 306
>gi|205360987 TBP-associated factor 1B [Homo sapiens]
Length = 588
Score = 32.3 bits (72), Expect = 1.5
Identities = 29/118 (24%), Positives = 47/118 (39%), Gaps = 23/118 (19%)
Query: 276 RKQNNIITHDQDYSNFSSSMEKESEDGPVSW---------DQTCFSARQLVEIFLQKGLS 326
+K+ ++ + +S S + P S+ D+TCF L + +KG S
Sbjct: 445 KKREMVVNLQKQFSTLVESTATAGKKSPSSFQFNWTEEDTDRTCFHGHSLQGVLKEKGQS 504
Query: 327 LISKEDFKQMSPGIIQQLLSCSC-HLPKDQQAKLPPTTLEKYGYSTVAVTLLTLGSML 383
L++K +S Q+ C C H+ TT E+ YS +L L S L
Sbjct: 505 LLTKNSLYWLS---TQKFCRCYCTHV----------TTYEESNYSLSYQFILNLFSFL 549
>gi|168480072 BCL2-related protein A1 isoform 2 [Homo sapiens]
Length = 163
Score = 32.0 bits (71), Expect = 2.0
Identities = 20/61 (32%), Positives = 35/61 (57%), Gaps = 8/61 (13%)
Query: 280 NIITHDQDYSNFSSSMEKESEDGPVSWDQTCFSARQLVEIFLQKGLSLISKEDFKQMSPG 339
N+++ D + F+ MEKE EDG ++W ++V IF +G+ LI K +Q++P
Sbjct: 60 NVVSVDTARTLFNQVMEKEFEDGIINWG-------RIVTIFAFEGI-LIKKLLRQQIAPD 111
Query: 340 I 340
+
Sbjct: 112 V 112
>gi|4757840 BCL2-related protein A1 isoform 1 [Homo sapiens]
Length = 175
Score = 32.0 bits (71), Expect = 2.0
Identities = 20/61 (32%), Positives = 35/61 (57%), Gaps = 8/61 (13%)
Query: 280 NIITHDQDYSNFSSSMEKESEDGPVSWDQTCFSARQLVEIFLQKGLSLISKEDFKQMSPG 339
N+++ D + F+ MEKE EDG ++W ++V IF +G+ LI K +Q++P
Sbjct: 60 NVVSVDTARTLFNQVMEKEFEDGIINWG-------RIVTIFAFEGI-LIKKLLRQQIAPD 111
Query: 340 I 340
+
Sbjct: 112 V 112
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.134 0.394
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,000,001
Number of Sequences: 37866
Number of extensions: 1073039
Number of successful extensions: 3038
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 27
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 2914
Number of HSP's gapped (non-prelim): 60
length of query: 691
length of database: 18,247,518
effective HSP length: 109
effective length of query: 582
effective length of database: 14,120,124
effective search space: 8217912168
effective search space used: 8217912168
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.