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Search of human proteins with 223633937
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|223633937 solute carrier family 39 (zinc transporter),
member 12 isoform 2 [Homo sapiens]
(654 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|223633937 solute carrier family 39 (zinc transporter), member... 1300 0.0
gi|223633939 solute carrier family 39 (zinc transporter), member... 1282 0.0
gi|115430255 solute carrier family 39 (zinc transporter), member... 275 1e-73
gi|115430259 solute carrier family 39 (zinc transporter), member... 271 2e-72
gi|205830424 solute carrier family 39 (zinc transporter), member... 186 8e-47
gi|190360568 solute carrier family 39 (zinc transporter), member... 186 8e-47
gi|190358541 solute carrier family 39 (zinc transporter), member... 180 3e-45
gi|24586665 solute carrier family 39 (zinc transporter), member ... 173 4e-43
gi|205830403 solute carrier family 39 (zinc transporter), member... 173 4e-43
gi|205830407 solute carrier family 39 (zinc transporter), member... 172 1e-42
gi|205830426 solute carrier family 39 (zinc transporter), member... 166 6e-41
gi|206597541 solute carrier family 39 (metal ion transporter), m... 162 7e-40
gi|206597539 solute carrier family 39 (metal ion transporter), m... 162 7e-40
gi|187936949 solute carrier family 39 (zinc transporter), member... 161 2e-39
gi|55741750 solute carrier family 39 (zinc transporter), member ... 161 2e-39
gi|205830405 solute carrier family 39 (zinc transporter), member... 157 3e-38
gi|153252201 solute carrier family 39 (zinc transporter), member... 156 6e-38
gi|153252214 solute carrier family 39 (zinc transporter), member... 128 2e-29
gi|117553619 solute carrier family 39, member 7 [Homo sapiens] 127 4e-29
gi|117553608 solute carrier family 39, member 7 [Homo sapiens] 127 4e-29
gi|40255101 solute carrier family 39 (zinc transporter), member ... 103 4e-22
gi|190014617 solute carrier family 39 (zinc transporter), member... 101 2e-21
gi|40254928 solute carrier family 39 (zinc transporter), member ... 59 1e-08
gi|156415986 solute carrier family 39 (zinc transporter), member... 46 1e-04
gi|21361423 solute carrier family 39 (zinc transporter), member ... 42 0.002
gi|229577422 solute carrier family 39, member 11 isoform 1 [Homo... 34 0.37
gi|229577418 solute carrier family 39, member 11 isoform 2 [Homo... 34 0.37
gi|205360987 TBP-associated factor 1B [Homo sapiens] 32 1.4
gi|168480072 BCL2-related protein A1 isoform 2 [Homo sapiens] 32 1.8
gi|4757840 BCL2-related protein A1 isoform 1 [Homo sapiens] 32 1.8
>gi|223633937 solute carrier family 39 (zinc transporter), member 12
isoform 2 [Homo sapiens]
Length = 654
Score = 1300 bits (3365), Expect = 0.0
Identities = 654/654 (100%), Positives = 654/654 (100%)
Query: 1 MCFRTKLSVSWVPLFLLLSRVFSTETDKPSAQDSRSRGSSGQPADLLQVLSAGDHPPHNH 60
MCFRTKLSVSWVPLFLLLSRVFSTETDKPSAQDSRSRGSSGQPADLLQVLSAGDHPPHNH
Sbjct: 1 MCFRTKLSVSWVPLFLLLSRVFSTETDKPSAQDSRSRGSSGQPADLLQVLSAGDHPPHNH 60
Query: 61 SRSLIKTLLEKTGCPRRRNGMQGDCNLCFEPDALLLIAGGNFEDQLREEVVQRVSLLLLY 120
SRSLIKTLLEKTGCPRRRNGMQGDCNLCFEPDALLLIAGGNFEDQLREEVVQRVSLLLLY
Sbjct: 61 SRSLIKTLLEKTGCPRRRNGMQGDCNLCFEPDALLLIAGGNFEDQLREEVVQRVSLLLLY 120
Query: 121 YIIHQEEICSSKLNMSNKEYKFYLHSLLSLRQDEDSSFLSQNETEDILAFTRQYFDTSQS 180
YIIHQEEICSSKLNMSNKEYKFYLHSLLSLRQDEDSSFLSQNETEDILAFTRQYFDTSQS
Sbjct: 121 YIIHQEEICSSKLNMSNKEYKFYLHSLLSLRQDEDSSFLSQNETEDILAFTRQYFDTSQS 180
Query: 181 QCMETKTLQKKSGIVSSEGANESTLPQLAAMIITLSLQGVCLGQGNLPSPDYFTEYIFSS 240
QCMETKTLQKKSGIVSSEGANESTLPQLAAMIITLSLQGVCLGQGNLPSPDYFTEYIFSS
Sbjct: 181 QCMETKTLQKKSGIVSSEGANESTLPQLAAMIITLSLQGVCLGQGNLPSPDYFTEYIFSS 240
Query: 241 LNRTNTLRLSELDQLLNTLWTRSTCIKNEKIHQFQRKQNNIITHDQDYSNFSSSMEKESE 300
LNRTNTLRLSELDQLLNTLWTRSTCIKNEKIHQFQRKQNNIITHDQDYSNFSSSMEKESE
Sbjct: 241 LNRTNTLRLSELDQLLNTLWTRSTCIKNEKIHQFQRKQNNIITHDQDYSNFSSSMEKESE 300
Query: 301 DGPVSWDQTCFSARQLVEIFLQKGLSLISKEDFKQMSPGIIQQLLSCSCHLPKDQQAKLP 360
DGPVSWDQTCFSARQLVEIFLQKGLSLISKEDFKQMSPGIIQQLLSCSCHLPKDQQAKLP
Sbjct: 301 DGPVSWDQTCFSARQLVEIFLQKGLSLISKEDFKQMSPGIIQQLLSCSCHLPKDQQAKLP 360
Query: 361 PTTLEKYGYSTVAVTLLTLGSMLGTALVLFHSCEENYRLILQLFVGLAVGTLSGDALLHL 420
PTTLEKYGYSTVAVTLLTLGSMLGTALVLFHSCEENYRLILQLFVGLAVGTLSGDALLHL
Sbjct: 361 PTTLEKYGYSTVAVTLLTLGSMLGTALVLFHSCEENYRLILQLFVGLAVGTLSGDALLHL 420
Query: 421 IPQVLGLHKQEAPEFGHFHESKGHIWKLMGLIGGIHGFFLIEKCFILLVSPNDKKSPEDS 480
IPQVLGLHKQEAPEFGHFHESKGHIWKLMGLIGGIHGFFLIEKCFILLVSPNDKKSPEDS
Sbjct: 421 IPQVLGLHKQEAPEFGHFHESKGHIWKLMGLIGGIHGFFLIEKCFILLVSPNDKKSPEDS 480
Query: 481 QAAEMPIGSMTASNRKCKAISLLAIMILVGDSLHNFADGLAIGAAFSSSSESGVTTTIAI 540
QAAEMPIGSMTASNRKCKAISLLAIMILVGDSLHNFADGLAIGAAFSSSSESGVTTTIAI
Sbjct: 481 QAAEMPIGSMTASNRKCKAISLLAIMILVGDSLHNFADGLAIGAAFSSSSESGVTTTIAI 540
Query: 541 LCHEIPHEMGDFAVLLSSGLSMKTAILMNFISSLTAFMGLYIGLSVSADPCVQDWIFTVT 600
LCHEIPHEMGDFAVLLSSGLSMKTAILMNFISSLTAFMGLYIGLSVSADPCVQDWIFTVT
Sbjct: 541 LCHEIPHEMGDFAVLLSSGLSMKTAILMNFISSLTAFMGLYIGLSVSADPCVQDWIFTVT 600
Query: 601 AGMFLYLSLVEMLPEMTHVQTQRPWMMFLLQNFGLILGWLSLLLLAIYEQNIKI 654
AGMFLYLSLVEMLPEMTHVQTQRPWMMFLLQNFGLILGWLSLLLLAIYEQNIKI
Sbjct: 601 AGMFLYLSLVEMLPEMTHVQTQRPWMMFLLQNFGLILGWLSLLLLAIYEQNIKI 654
>gi|223633939 solute carrier family 39 (zinc transporter), member 12
isoform 1 [Homo sapiens]
Length = 691
Score = 1282 bits (3317), Expect = 0.0
Identities = 654/691 (94%), Positives = 654/691 (94%), Gaps = 37/691 (5%)
Query: 1 MCFRTKLSVSWVPLFLLLSRVFSTETDKPSAQDSRSRGSSGQPADLLQVLSAGDHPPHNH 60
MCFRTKLSVSWVPLFLLLSRVFSTETDKPSAQDSRSRGSSGQPADLLQVLSAGDHPPHNH
Sbjct: 1 MCFRTKLSVSWVPLFLLLSRVFSTETDKPSAQDSRSRGSSGQPADLLQVLSAGDHPPHNH 60
Query: 61 SRSLIKTLLEKTGCPRRRNGMQGDCNLCFEPDALLLIAGGNFEDQLREEVVQRVSLLLLY 120
SRSLIKTLLEKTGCPRRRNGMQGDCNLCFEPDALLLIAGGNFEDQLREEVVQRVSLLLLY
Sbjct: 61 SRSLIKTLLEKTGCPRRRNGMQGDCNLCFEPDALLLIAGGNFEDQLREEVVQRVSLLLLY 120
Query: 121 YIIHQEEICSSKLNMSNKEYKFYLHSLLSLRQDEDSSFLSQNETEDILAFTRQYFDTSQS 180
YIIHQEEICSSKLNMSNKEYKFYLHSLLSLRQDEDSSFLSQNETEDILAFTRQYFDTSQS
Sbjct: 121 YIIHQEEICSSKLNMSNKEYKFYLHSLLSLRQDEDSSFLSQNETEDILAFTRQYFDTSQS 180
Query: 181 QCMETKTLQKKSGIVSSEGANESTLPQLAAMIITLSLQGVCLGQGNLPSPDYFTEYIFSS 240
QCMETKTLQKKSGIVSSEGANESTLPQLAAMIITLSLQGVCLGQGNLPSPDYFTEYIFSS
Sbjct: 181 QCMETKTLQKKSGIVSSEGANESTLPQLAAMIITLSLQGVCLGQGNLPSPDYFTEYIFSS 240
Query: 241 LNRTNTLRLSELDQLLNTLWTRSTCIKNEKIHQFQRKQNNIITHDQDYSNFSSSMEKESE 300
LNRTNTLRLSELDQLLNTLWTRSTCIKNEKIHQFQRKQNNIITHDQDYSNFSSSMEKESE
Sbjct: 241 LNRTNTLRLSELDQLLNTLWTRSTCIKNEKIHQFQRKQNNIITHDQDYSNFSSSMEKESE 300
Query: 301 DGPVSWDQTCFSARQLVEIFLQKGLSLISKEDFKQMSPGIIQQLLSCSCHLPKDQQAKLP 360
DGPVSWDQTCFSARQLVEIFLQKGLSLISKEDFKQMSPGIIQQLLSCSCHLPKDQQAKLP
Sbjct: 301 DGPVSWDQTCFSARQLVEIFLQKGLSLISKEDFKQMSPGIIQQLLSCSCHLPKDQQAKLP 360
Query: 361 PTTLEKYGYSTVAVTLLTLGSMLGTALVLFHSCEENYRLILQLFVGLAVGTLSGDALLHL 420
PTTLEKYGYSTVAVTLLTLGSMLGTALVLFHSCEENYRLILQLFVGLAVGTLSGDALLHL
Sbjct: 361 PTTLEKYGYSTVAVTLLTLGSMLGTALVLFHSCEENYRLILQLFVGLAVGTLSGDALLHL 420
Query: 421 IPQVLGLHKQEAPEFGHFHESKGHIWKLMGLIGGIHGFFLIEKCFILLVSPNDK------ 474
IPQVLGLHKQEAPEFGHFHESKGHIWKLMGLIGGIHGFFLIEKCFILLVSPNDK
Sbjct: 421 IPQVLGLHKQEAPEFGHFHESKGHIWKLMGLIGGIHGFFLIEKCFILLVSPNDKQGLSLV 480
Query: 475 -------------------------------KSPEDSQAAEMPIGSMTASNRKCKAISLL 503
KSPEDSQAAEMPIGSMTASNRKCKAISLL
Sbjct: 481 NGHVGHSHHLALNSELSDQAGRGKSASTIQLKSPEDSQAAEMPIGSMTASNRKCKAISLL 540
Query: 504 AIMILVGDSLHNFADGLAIGAAFSSSSESGVTTTIAILCHEIPHEMGDFAVLLSSGLSMK 563
AIMILVGDSLHNFADGLAIGAAFSSSSESGVTTTIAILCHEIPHEMGDFAVLLSSGLSMK
Sbjct: 541 AIMILVGDSLHNFADGLAIGAAFSSSSESGVTTTIAILCHEIPHEMGDFAVLLSSGLSMK 600
Query: 564 TAILMNFISSLTAFMGLYIGLSVSADPCVQDWIFTVTAGMFLYLSLVEMLPEMTHVQTQR 623
TAILMNFISSLTAFMGLYIGLSVSADPCVQDWIFTVTAGMFLYLSLVEMLPEMTHVQTQR
Sbjct: 601 TAILMNFISSLTAFMGLYIGLSVSADPCVQDWIFTVTAGMFLYLSLVEMLPEMTHVQTQR 660
Query: 624 PWMMFLLQNFGLILGWLSLLLLAIYEQNIKI 654
PWMMFLLQNFGLILGWLSLLLLAIYEQNIKI
Sbjct: 661 PWMMFLLQNFGLILGWLSLLLLAIYEQNIKI 691
>gi|115430255 solute carrier family 39 (zinc transporter), member 4
isoform 2 [Homo sapiens]
Length = 647
Score = 275 bits (703), Expect = 1e-73
Identities = 200/664 (30%), Positives = 311/664 (46%), Gaps = 89/664 (13%)
Query: 39 SSGQPADLLQVLSAGDHPPHNHSRS-LIKTLLEKTGCPRRRNGMQGDCNLCF-------- 89
++ PA LL +L++G + L+ TL ++ C G C C
Sbjct: 21 TASPPAGLLSLLTSGQGALDQEALGGLLNTLADRVHCAN------GPCGKCLSVEDALGL 74
Query: 90 -EPDALLLIAGGNFEDQLREEVVQRVSLLLLYYIIHQEEICSSKLNMSNKEYKFYLHSLL 148
EP+ L G L V R+S + Y+ + E C + +L +LL
Sbjct: 75 GEPEGSGLPPG----PVLEARYVARLSAAAVLYLSNPEGTCEDARAGLWASHADHLLALL 130
Query: 149 SLRQ--DEDSSFLSQNETEDILAFTRQYFDTSQSQCMETKTLQKKSGIVSSEGANESTLP 206
+ S+L Q R T ++ C++ L +++ + G+ L
Sbjct: 131 ESPKALTPGLSWLLQRMQ------ARAAGQTPKTACVDIPQLLEEAVGAGAPGSAGGVL- 183
Query: 207 QLAAMIITLSLQGVCLGQGNLPSPDYFTEYIFSSLNRTNTLRLSELDQLLNTLWTRSTCI 266
A ++ G C LPSP YF +++F + + L+EL L+ L
Sbjct: 184 ---AALLDHVRSGSCFHA--LPSPQYFVDFVFQQHSSEVPMTLAELSALMQRLGV----- 233
Query: 267 KNEKIHQFQRKQNNIITHDQDYSNFSSSMEKESEDGPVSWDQTCFSARQLVEIFLQKGLS 326
+ H ++ + SSS WD C SAR ++ + +
Sbjct: 234 -GREAHSDHSHRHRGASSRDPVPLISSSNSSSV------WDTVCLSARDVMAAYGLSEQA 286
Query: 327 LISKEDFKQMSPGIIQQLLSCSCHLPKDQQAKLPPTTLEKYGYSTVAVTLLTLGSMLGTA 386
++ E + Q+SP ++QQ LS +C + + E+Y Y ++A L+ L ++ G
Sbjct: 287 GVTPEAWAQLSPALLQQQLSGACTSQSRPPVQDQLSQSERYLYGSLATLLICLCAVFGLL 346
Query: 387 LVLFHSCEENYRLILQLFVGLAVGTLSGDALLHLIPQVLGLHKQEAPEFGHFHESKGHIW 446
L+ C ILQ F+ LAVG L+GDA+LHL P+VLGLH S W
Sbjct: 347 LLTCTGCRGVTHYILQTFLSLAVGALTGDAVLHLTPKVLGLHTHSEEGL-----SPQPTW 401
Query: 447 KLMGLIGGIHGFFLIEKCFILLV------------------------------SPNDKKS 476
+L+ ++ G++ FFL E F LL+ +P++ +
Sbjct: 402 RLLAMLAGLYAFFLFENLFNLLLPRDPEDLEDGPCGHSSHSHGGHSHGVSLQLAPSELRQ 461
Query: 477 PE--------DSQAAEMPIGSMTASNRKCKAISLLAIMILVGDSLHNFADGLAIGAAFSS 528
P+ D A E P R + LL MI +GD++HNFADGLA+GAAF+S
Sbjct: 462 PKPPHEGSRADLVAEESPELLNPEPRRLSPELRLLPYMITLGDAVHNFADGLAVGAAFAS 521
Query: 529 SSESGVTTTIAILCHEIPHEMGDFAVLLSSGLSMKTAILMNFISSLTAFMGLYIGLSVSA 588
S ++G+ T++A+ CHE+PHE+GDFA LL +GLS++ A+L+N S+LTAF GLY+ L+V
Sbjct: 522 SWKTGLATSLAVFCHELPHELGDFAALLHAGLSVRQALLLNLASALTAFAGLYVALAVGV 581
Query: 589 DPCVQDWIFTVTAGMFLYLSLVEMLPEMTHVQTQRPWMMFLLQNFGLILGWLSLLLLAIY 648
+ WI V G+FLY++L +MLP M V+ RPW++FLL N GL+ GW LLLL++Y
Sbjct: 582 SEESEAWILAVATGLFLYVALCDMLPAMLKVRDPRPWLLFLLHNVGLLGGWTVLLLLSLY 641
Query: 649 EQNI 652
E +I
Sbjct: 642 EDDI 645
>gi|115430259 solute carrier family 39 (zinc transporter), member 4
isoform 1 [Homo sapiens]
Length = 622
Score = 271 bits (692), Expect = 2e-72
Identities = 161/464 (34%), Positives = 242/464 (52%), Gaps = 55/464 (11%)
Query: 227 LPSPDYFTEYIFSSLNRTNTLRLSELDQLLNTLWTRSTCIKNEKIHQFQRKQNNIITHDQ 286
LPSP YF +++F + + L+EL L+ L + H ++ +
Sbjct: 174 LPSPQYFVDFVFQQHSSEVPMTLAELSALMQRLGV------GREAHSDHSHRHRGASSRD 227
Query: 287 DYSNFSSSMEKESEDGPVSWDQTCFSARQLVEIFLQKGLSLISKEDFKQMSPGIIQQLLS 346
SSS WD C SAR ++ + + ++ E + Q+SP ++QQ LS
Sbjct: 228 PVPLISSSNSSSV------WDTVCLSARDVMAAYGLSEQAGVTPEAWAQLSPALLQQQLS 281
Query: 347 CSCHLPKDQQAKLPPTTLEKYGYSTVAVTLLTLGSMLGTALVLFHSCEENYRLILQLFVG 406
+C + + E+Y Y ++A L+ L ++ G L+ C ILQ F+
Sbjct: 282 GACTSQSRPPVQDQLSQSERYLYGSLATLLICLCAVFGLLLLTCTGCRGVTHYILQTFLS 341
Query: 407 LAVGTLSGDALLHLIPQVLGLHKQEAPEFGHFHESKGHIWKLMGLIGGIHGFFLIEKCFI 466
LAVG L+GDA+LHL P+VLGLH S W+L+ ++ G++ FFL E F
Sbjct: 342 LAVGALTGDAVLHLTPKVLGLHTHSEEGL-----SPQPTWRLLAMLAGLYAFFLFENLFN 396
Query: 467 LLV------------------------------SPNDKKSPE--------DSQAAEMPIG 488
LL+ +P++ + P+ D A E P
Sbjct: 397 LLLPRDPEDLEDGPCGHSSHSHGGHSHGVSLQLAPSELRQPKPPHEGSRADLVAEESPEL 456
Query: 489 SMTASNRKCKAISLLAIMILVGDSLHNFADGLAIGAAFSSSSESGVTTTIAILCHEIPHE 548
R + LL MI +GD++HNFADGLA+GAAF+SS ++G+ T++A+ CHE+PHE
Sbjct: 457 LNPEPRRLSPELRLLPYMITLGDAVHNFADGLAVGAAFASSWKTGLATSLAVFCHELPHE 516
Query: 549 MGDFAVLLSSGLSMKTAILMNFISSLTAFMGLYIGLSVSADPCVQDWIFTVTAGMFLYLS 608
+GDFA LL +GLS++ A+L+N S+LTAF GLY+ L+V + WI V G+FLY++
Sbjct: 517 LGDFAALLHAGLSVRQALLLNLASALTAFAGLYVALAVGVSEESEAWILAVATGLFLYVA 576
Query: 609 LVEMLPEMTHVQTQRPWMMFLLQNFGLILGWLSLLLLAIYEQNI 652
L +MLP M V+ RPW++FLL N GL+ GW LLLL++YE +I
Sbjct: 577 LCDMLPAMLKVRDPRPWLLFLLHNVGLLGGWTVLLLLSLYEDDI 620
>gi|205830424 solute carrier family 39 (zinc transporter), member 14
isoform a [Homo sapiens]
Length = 492
Score = 186 bits (471), Expect = 8e-47
Identities = 136/445 (30%), Positives = 216/445 (48%), Gaps = 96/445 (21%)
Query: 278 QNNIITHDQDYSNFSSSMEKESEDGPVSWDQTCFSARQLVEIFLQKGLSLISKEDFKQMS 337
+ N+ H Q + N S TCFS+ L S I + ++
Sbjct: 75 RGNVTQHVQGHRNLS----------------TCFSSGDLFTAHNFSEQSRIGSSELQEFC 118
Query: 338 PGIIQQLLSCSC------HLPKDQQAKLPPTTLEKYGYSTVAVTLLTLGSMLGTALVLFH 391
P I+QQL S +C + +Q + P+ +E +GY + VT+++L S+LG ++V F
Sbjct: 119 PTILQQLDSRACTSENQENEENEQTEEGRPSAVEVWGYGLLCVTVISLCSLLGASVVPFM 178
Query: 392 SCEENYRLILQLFVGLAVGTLSGDALLHLIPQVLGLHKQEAPEFGHFHESKGHIWKLMGL 451
+ Y+ +L F+ LA+GTL +AL LIP+ G + E ++ SK + +
Sbjct: 179 K-KTFYKRLLLYFIALAIGTLYSNALFQLIPEAFGFNPLE-----DYYVSKSAV-----V 227
Query: 452 IGGIHGFFLIEKCF-ILLVSPND---------------KKSPEDSQAAEMP--------- 486
GG + FF EK ILL N+ KK E+ ++
Sbjct: 228 FGGFYLFFFTEKILKILLKQKNEHHHGHSHYASESLPSKKDQEEGVMEKLQNGDLDHMIP 287
Query: 487 -------------------IGSMT-----ASNRKC--------KAISLLAIMILVGDSLH 514
+GS++ AS C I LA MI + D LH
Sbjct: 288 QHCSSELDGKAPMVDEKVIVGSLSVQDLQASQSACYWLKGVRYSDIGTLAWMITLSDGLH 347
Query: 515 NFADGLAIGAAFSSSSESGVTTTIAILCHEIPHEMGDFAVLLSSGLSMKTAILMNFISSL 574
NF DGLAIGA+F+ S G++T++AILC E PHE+GDF +LL++G+S++ A+ NF+S+
Sbjct: 348 NFIDGLAIGASFTVSVFQGISTSVAILCEEFPHELGDFVILLNAGMSIQQALFFNFLSAC 407
Query: 575 TAFMGLYIGLSVSADPCVQDWIFTVTAGMFLYLSLVEMLPEMTHV--QTQRPWMM---FL 629
++GL G+ ++ +WIF + GMFLY+SL +M PEM V + +R + F+
Sbjct: 408 CCYLGLAFGI-LAGSHFSANWIFALAGGMFLYISLADMFPEMNEVCQEDERKGSILIPFI 466
Query: 630 LQNFGLILGWLSLLLLAIYEQNIKI 654
+QN GL+ G+ +++L +Y I+I
Sbjct: 467 IQNLGLLTGFTIMVVLTMYSGQIQI 491
>gi|190360568 solute carrier family 39 (zinc transporter), member 14
isoform a [Homo sapiens]
Length = 492
Score = 186 bits (471), Expect = 8e-47
Identities = 136/445 (30%), Positives = 216/445 (48%), Gaps = 96/445 (21%)
Query: 278 QNNIITHDQDYSNFSSSMEKESEDGPVSWDQTCFSARQLVEIFLQKGLSLISKEDFKQMS 337
+ N+ H Q + N S TCFS+ L S I + ++
Sbjct: 75 RGNVTQHVQGHRNLS----------------TCFSSGDLFTAHNFSEQSRIGSSELQEFC 118
Query: 338 PGIIQQLLSCSC------HLPKDQQAKLPPTTLEKYGYSTVAVTLLTLGSMLGTALVLFH 391
P I+QQL S +C + +Q + P+ +E +GY + VT+++L S+LG ++V F
Sbjct: 119 PTILQQLDSRACTSENQENEENEQTEEGRPSAVEVWGYGLLCVTVISLCSLLGASVVPFM 178
Query: 392 SCEENYRLILQLFVGLAVGTLSGDALLHLIPQVLGLHKQEAPEFGHFHESKGHIWKLMGL 451
+ Y+ +L F+ LA+GTL +AL LIP+ G + E ++ SK + +
Sbjct: 179 K-KTFYKRLLLYFIALAIGTLYSNALFQLIPEAFGFNPLE-----DYYVSKSAV-----V 227
Query: 452 IGGIHGFFLIEKCF-ILLVSPND---------------KKSPEDSQAAEMP--------- 486
GG + FF EK ILL N+ KK E+ ++
Sbjct: 228 FGGFYLFFFTEKILKILLKQKNEHHHGHSHYASESLPSKKDQEEGVMEKLQNGDLDHMIP 287
Query: 487 -------------------IGSMT-----ASNRKC--------KAISLLAIMILVGDSLH 514
+GS++ AS C I LA MI + D LH
Sbjct: 288 QHCSSELDGKAPMVDEKVIVGSLSVQDLQASQSACYWLKGVRYSDIGTLAWMITLSDGLH 347
Query: 515 NFADGLAIGAAFSSSSESGVTTTIAILCHEIPHEMGDFAVLLSSGLSMKTAILMNFISSL 574
NF DGLAIGA+F+ S G++T++AILC E PHE+GDF +LL++G+S++ A+ NF+S+
Sbjct: 348 NFIDGLAIGASFTVSVFQGISTSVAILCEEFPHELGDFVILLNAGMSIQQALFFNFLSAC 407
Query: 575 TAFMGLYIGLSVSADPCVQDWIFTVTAGMFLYLSLVEMLPEMTHV--QTQRPWMM---FL 629
++GL G+ ++ +WIF + GMFLY+SL +M PEM V + +R + F+
Sbjct: 408 CCYLGLAFGI-LAGSHFSANWIFALAGGMFLYISLADMFPEMNEVCQEDERKGSILIPFI 466
Query: 630 LQNFGLILGWLSLLLLAIYEQNIKI 654
+QN GL+ G+ +++L +Y I+I
Sbjct: 467 IQNLGLLTGFTIMVVLTMYSGQIQI 491
>gi|190358541 solute carrier family 39 (zinc transporter), member 14
isoform b [Homo sapiens]
Length = 492
Score = 180 bits (457), Expect = 3e-45
Identities = 135/447 (30%), Positives = 214/447 (47%), Gaps = 100/447 (22%)
Query: 278 QNNIITHDQDYSNFSSSMEKESEDGPVSWDQTCFSARQLVEIFLQKGLSLISKEDFKQMS 337
+ N+ H Q + N S TCFS+ L S I + ++
Sbjct: 75 RGNVTQHVQGHRNLS----------------TCFSSGDLFTAHNFSEQSRIGSSELQEFC 118
Query: 338 PGIIQQLLSCSC------HLPKDQQAKLPPTTLEKYGYSTVAVTLLTLGSMLGTALVLFH 391
P I+QQL S +C + +Q + P+ +E +G+ ++V+L+ L S+LG VL
Sbjct: 119 PTILQQLDSRACTSENQENEENEQTEEGRPSAVEVWGFGFLSVSLINLASLLG---VLVL 175
Query: 392 SCEEN--YRLILQLFVGLAVGTLSGDALLHLIPQVLGLHKQEAPEFGHFHESKGHIWKLM 449
C E + +L F+ L++GTL +AL LIP+ G + E ++ SK +
Sbjct: 176 PCTEKAFFSRVLTYFIALSIGTLLSNALFQLIPEAFGFNPLE-----DYYVSKSAV---- 226
Query: 450 GLIGGIHGFFLIEKCF-ILLVSPND---------------KKSPEDSQAAEMP------- 486
+ GG + FF EK ILL N+ KK E+ ++
Sbjct: 227 -VFGGFYLFFFTEKILKILLKQKNEHHHGHSHYASESLPSKKDQEEGVMEKLQNGDLDHM 285
Query: 487 ---------------------IGSMT-----ASNRKC--------KAISLLAIMILVGDS 512
+GS++ AS C I LA MI + D
Sbjct: 286 IPQHCSSELDGKAPMVDEKVIVGSLSVQDLQASQSACYWLKGVRYSDIGTLAWMITLSDG 345
Query: 513 LHNFADGLAIGAAFSSSSESGVTTTIAILCHEIPHEMGDFAVLLSSGLSMKTAILMNFIS 572
LHNF DGLAIGA+F+ S G++T++AILC E PHE+GDF +LL++G+S++ A+ NF+S
Sbjct: 346 LHNFIDGLAIGASFTVSVFQGISTSVAILCEEFPHELGDFVILLNAGMSIQQALFFNFLS 405
Query: 573 SLTAFMGLYIGLSVSADPCVQDWIFTVTAGMFLYLSLVEMLPEMTHV--QTQRPWMM--- 627
+ ++GL G+ ++ +WIF + GMFLY+SL +M PEM V + +R +
Sbjct: 406 ACCCYLGLAFGI-LAGSHFSANWIFALAGGMFLYISLADMFPEMNEVCQEDERKGSILIP 464
Query: 628 FLLQNFGLILGWLSLLLLAIYEQNIKI 654
F++QN GL+ G+ +++L +Y I+I
Sbjct: 465 FIIQNLGLLTGFTIMVVLTMYSGQIQI 491
>gi|24586665 solute carrier family 39 (zinc transporter), member 8
isoform a [Homo sapiens]
Length = 460
Score = 173 bits (439), Expect = 4e-43
Identities = 121/412 (29%), Positives = 201/412 (48%), Gaps = 74/412 (17%)
Query: 300 EDGPVSWDQTCFSARQLVEIFLQKGLSLISKEDFKQMSPGIIQQLLSCSCH-LPKDQQAK 358
E G + ++Q C +A ++ + + I+ F + P ++QQL C PK K
Sbjct: 65 EPGQLHFNQ-CLTAEEIFSLHGFSNATQITSSKFSVICPAVLQQLNFHPCEDRPKH---K 120
Query: 359 LPPTTLEKYGYSTVAVTLLTLGSMLGTALVLFHSCEENY-RLILQLFVGLAVGTLSGDAL 417
P+ E +GY ++VT++ L S+LG L+L +++Y IL FVGLA+GTL +A+
Sbjct: 121 TRPSHSEVWGYGFLSVTIINLASLLG--LILTPLIKKSYFPKILTFFVGLAIGTLFSNAI 178
Query: 418 LHLIPQVLGLHKQEAPEFGHFHESKGHIWKLMGLIGGIHGFFLIEKCFILLVSP------ 471
LIP+ FG + ++ K + + GG + F E+ +L+
Sbjct: 179 FQLIPEA----------FGFDPKVDSYVEKAVAVFGGFYLLFFFERMLKMLLKTYGQNGH 228
Query: 472 ----NDKKSPEDS---------------------------------------QAAEMPIG 488
ND P++ + P
Sbjct: 229 THFGNDNFGPQEKTHQPKALPAINGVTCYANPAVTEANGHIHFDNVSVVSLQDGKKEPSS 288
Query: 489 SMTASNRKCKAISLLAIMILVGDSLHNFADGLAIGAAFSSSSESGVTTTIAILCHEIPHE 548
K I +A MI + D+LHNF DGLAIGA+ + S G++T+IAILC E PHE
Sbjct: 289 CTCLKGPKLSEIGTIAWMITLCDALHNFIDGLAIGASCTLSLLQGLSTSIAILCEEFPHE 348
Query: 549 MGDFAVLLSSGLSMKTAILMNFISSLTAFMGLYIGLSVSADPCVQDWIFTVTAGMFLYLS 608
+GDF +LL++G+S + A+L NF+S+ + ++GL G+ V + + IF + GMFLY+S
Sbjct: 349 LGDFVILLNAGMSTRQALLFNFLSACSCYVGLAFGILV-GNNFAPNIIFALAGGMFLYIS 407
Query: 609 LVEMLPEMTHVQTQR------PWMMFLLQNFGLILGWLSLLLLAIYEQNIKI 654
L +M PEM + ++ + F++QN G++ G+ ++LL+ +Y I++
Sbjct: 408 LADMFPEMNDMLREKVTGRKTDFTFFMIQNAGMLTGFTAILLITLYAGEIEL 459
>gi|205830403 solute carrier family 39 (zinc transporter), member 8
isoform a [Homo sapiens]
Length = 460
Score = 173 bits (439), Expect = 4e-43
Identities = 121/412 (29%), Positives = 201/412 (48%), Gaps = 74/412 (17%)
Query: 300 EDGPVSWDQTCFSARQLVEIFLQKGLSLISKEDFKQMSPGIIQQLLSCSCH-LPKDQQAK 358
E G + ++Q C +A ++ + + I+ F + P ++QQL C PK K
Sbjct: 65 EPGQLHFNQ-CLTAEEIFSLHGFSNATQITSSKFSVICPAVLQQLNFHPCEDRPKH---K 120
Query: 359 LPPTTLEKYGYSTVAVTLLTLGSMLGTALVLFHSCEENY-RLILQLFVGLAVGTLSGDAL 417
P+ E +GY ++VT++ L S+LG L+L +++Y IL FVGLA+GTL +A+
Sbjct: 121 TRPSHSEVWGYGFLSVTIINLASLLG--LILTPLIKKSYFPKILTFFVGLAIGTLFSNAI 178
Query: 418 LHLIPQVLGLHKQEAPEFGHFHESKGHIWKLMGLIGGIHGFFLIEKCFILLVSP------ 471
LIP+ FG + ++ K + + GG + F E+ +L+
Sbjct: 179 FQLIPEA----------FGFDPKVDSYVEKAVAVFGGFYLLFFFERMLKMLLKTYGQNGH 228
Query: 472 ----NDKKSPEDS---------------------------------------QAAEMPIG 488
ND P++ + P
Sbjct: 229 THFGNDNFGPQEKTHQPKALPAINGVTCYANPAVTEANGHIHFDNVSVVSLQDGKKEPSS 288
Query: 489 SMTASNRKCKAISLLAIMILVGDSLHNFADGLAIGAAFSSSSESGVTTTIAILCHEIPHE 548
K I +A MI + D+LHNF DGLAIGA+ + S G++T+IAILC E PHE
Sbjct: 289 CTCLKGPKLSEIGTIAWMITLCDALHNFIDGLAIGASCTLSLLQGLSTSIAILCEEFPHE 348
Query: 549 MGDFAVLLSSGLSMKTAILMNFISSLTAFMGLYIGLSVSADPCVQDWIFTVTAGMFLYLS 608
+GDF +LL++G+S + A+L NF+S+ + ++GL G+ V + + IF + GMFLY+S
Sbjct: 349 LGDFVILLNAGMSTRQALLFNFLSACSCYVGLAFGILV-GNNFAPNIIFALAGGMFLYIS 407
Query: 609 LVEMLPEMTHVQTQR------PWMMFLLQNFGLILGWLSLLLLAIYEQNIKI 654
L +M PEM + ++ + F++QN G++ G+ ++LL+ +Y I++
Sbjct: 408 LADMFPEMNDMLREKVTGRKTDFTFFMIQNAGMLTGFTAILLITLYAGEIEL 459
>gi|205830407 solute carrier family 39 (zinc transporter), member 8
isoform c [Homo sapiens]
Length = 393
Score = 172 bits (435), Expect = 1e-42
Identities = 118/402 (29%), Positives = 195/402 (48%), Gaps = 73/402 (18%)
Query: 310 CFSARQLVEIFLQKGLSLISKEDFKQMSPGIIQQLLSCSCH-LPKDQQAKLPPTTLEKYG 368
C +A ++ + + I+ F + P ++QQL C PK K P+ E +G
Sbjct: 7 CLTAEEIFSLHGFSNATQITSSKFSVICPAVLQQLNFHPCEDRPKH---KTRPSHSEVWG 63
Query: 369 YSTVAVTLLTLGSMLGTALVLFHSCEENY-RLILQLFVGLAVGTLSGDALLHLIPQVLGL 427
Y ++VT++ L S+LG L+L +++Y IL FVGLA+GTL +A+ LIP+
Sbjct: 64 YGFLSVTIINLASLLG--LILTPLIKKSYFPKILTFFVGLAIGTLFSNAIFQLIPEA--- 118
Query: 428 HKQEAPEFGHFHESKGHIWKLMGLIGGIHGFFLIEKCFILLVSP----------NDKKSP 477
FG + ++ K + + GG + F E+ +L+ ND P
Sbjct: 119 -------FGFDPKVDSYVEKAVAVFGGFYLLFFFERMLKMLLKTYGQNGHTHFGNDNFGP 171
Query: 478 EDS---------------------------------------QAAEMPIGSMTASNRKCK 498
++ + P K
Sbjct: 172 QEKTHQPKALPAINGVTCYANPAVTEANGHIHFDNVSVVSLQDGKKEPSSCTCLKGPKLS 231
Query: 499 AISLLAIMILVGDSLHNFADGLAIGAAFSSSSESGVTTTIAILCHEIPHEMGDFAVLLSS 558
I +A MI + D+LHNF DGLAIGA+ + S G++T+IAILC E PHE+GDF +LL++
Sbjct: 232 EIGTIAWMITLCDALHNFIDGLAIGASCTLSLLQGLSTSIAILCEEFPHELGDFVILLNA 291
Query: 559 GLSMKTAILMNFISSLTAFMGLYIGLSVSADPCVQDWIFTVTAGMFLYLSLVEMLPEMTH 618
G+S + A+L NF+S+ + ++GL G+ V + + IF + GMFLY+SL +M PEM
Sbjct: 292 GMSTRQALLFNFLSACSCYVGLAFGILV-GNNFAPNIIFALAGGMFLYISLADMFPEMND 350
Query: 619 VQTQR------PWMMFLLQNFGLILGWLSLLLLAIYEQNIKI 654
+ ++ + F++QN G++ G+ ++LL+ +Y I++
Sbjct: 351 MLREKVTGRKTDFTFFMIQNAGMLTGFTAILLITLYAGEIEL 392
>gi|205830426 solute carrier family 39 (zinc transporter), member 14
isoform c [Homo sapiens]
Length = 481
Score = 166 bits (420), Expect = 6e-41
Identities = 131/432 (30%), Positives = 202/432 (46%), Gaps = 92/432 (21%)
Query: 278 QNNIITHDQDYSNFSSSMEKESEDGPVSWDQTCFSARQLVEIFLQKGLSLISKEDFKQMS 337
+ N+ H Q + N S TCFS+ L S I + ++
Sbjct: 75 RGNVTQHVQGHRNLS----------------TCFSSGDLFTAHNFSEQSRIGSSELQEFC 118
Query: 338 PGIIQQLLSCSC------HLPKDQQAKLPPTTLEKYGYSTVAVTLLTLGSMLGTALVLFH 391
P I+QQL S +C + +Q + P+ +E +GY + VT+++L S+LG ++V F
Sbjct: 119 PTILQQLDSRACTSENQENEENEQTEEGRPSAVEVWGYGLLCVTVISLCSLLGASVVPFM 178
Query: 392 SCEENYRLILQLFVGLAVGTLSGDALLHLIPQVLGLHKQEAPEFGHFHESKGHIWKLMGL 451
+ Y+ +L F+ LA+GTL +AL LIP+ G + E ++ SK + +
Sbjct: 179 K-KTFYKRLLLYFIALAIGTLYSNALFQLIPEAFGFNPLE-----DYYVSKSAV-----V 227
Query: 452 IGGIHGFFLIEKCF-ILLVSPND---------------KKSPEDSQAAEMP--------- 486
GG + FF EK ILL N+ KK E+ ++
Sbjct: 228 FGGFYLFFFTEKILKILLKQKNEHHHGHSHYASESLPSKKDQEEGVMEKLQNGDLDHMIP 287
Query: 487 -------------------IGSMT-----ASNRKC--------KAISLLAIMILVGDSLH 514
+GS++ AS C I LA MI + D LH
Sbjct: 288 QHCSSELDGKAPMVDEKVIVGSLSVQDLQASQSACYWLKGVRYSDIGTLAWMITLSDGLH 347
Query: 515 NFADGLAIGAAFSSSSESGVTTTIAILCHEIPHEMGDFAVLLSSGLSMKTAILMNFISSL 574
NF DGLAIGA+F+ S G++T++AILC E PHE+GDF +LL++G+S++ A+ NF+S+
Sbjct: 348 NFIDGLAIGASFTVSVFQGISTSVAILCEEFPHELGDFVILLNAGMSIQQALFFNFLSAC 407
Query: 575 TAFMGLYIGLSVSADPCVQDWIFTVTAGMFLYLSLVEMLPEMTHVQTQRPWM-MFLLQNF 633
++GL G+ ++ +WIF + GMFLY+SL +M+ + Q W + LQ
Sbjct: 408 CCYLGLAFGI-LAGSHFSANWIFALAGGMFLYISLADMMEFCSVAQAGVQWCHLSSLQPL 466
Query: 634 GLILGWLSLLLL 645
L L LS L L
Sbjct: 467 PLGLKRLSCLSL 478
>gi|206597541 solute carrier family 39 (metal ion transporter),
member 5 [Homo sapiens]
Length = 540
Score = 162 bits (411), Expect = 7e-40
Identities = 126/389 (32%), Positives = 186/389 (47%), Gaps = 53/389 (13%)
Query: 307 DQTCFSARQLVEIFLQKGLSLISKEDFKQMSPGIIQQLLSCSCHLPKDQQAKLPP-TTLE 365
++ C + QL+ F + ++ F + P ++ Q+ S C A PP L
Sbjct: 155 NEDCLNGSQLLVNFGLSPAAPLTPRQFALLCPALLYQIDSRVCI---GAPAPAPPGDLLS 211
Query: 366 KYGYSTVAVTLLTLGSMLGTALVLFHSCEENYRLILQLFVGLAVGTLSGDALLHLIPQVL 425
S +AV LL+L S L L+ R +L LAVGTL GDALLHL+P
Sbjct: 212 ALLQSALAVLLLSLPSPLSLLLLRLLG-PRLLRPLLGFLGALAVGTLCGDALLHLLP--- 267
Query: 426 GLHKQEAPEFGHFHESKGHIWKLMGLIGGIHGFFLIEKCFILL----VSPNDKK------ 475
H QE G + + + ++GG+ F++E LL + P +
Sbjct: 268 --HAQEGRHAGPGGLPEKDLGPGLSVLGGLFLLFVLENMLGLLRHRGLRPRCCRRKRRNL 325
Query: 476 -----SPEDS--------QAAEMPIGSMTASNRKCKAISLLAI----------------- 505
PE+ QAA P G+ + + LA
Sbjct: 326 ETRNLDPENGSGMALQPLQAAPEP-GAQGQREKNSQHPPALAPPGHQGHSHGHQGGTDIT 384
Query: 506 -MILVGDSLHNFADGLAIGAAFSSSSESGVTTTIAILCHEIPHEMGDFAVLLSSGLSMKT 564
M+L+GD LHN DGLAIGAAFS SG++TT+A+ CHE+PHE+GDFA+LL SGLS +
Sbjct: 385 WMVLLGDGLHNLTDGLAIGAAFSDGFSSGLSTTLAVFCHELPHELGDFAMLLQSGLSFRR 444
Query: 565 AILMNFISSLTAFMGLYIGLSVSADPC-VQDWIFTVTAGMFLYLSLVEMLPEMTHVQTQR 623
+L++ +S G +G+ +S P + W+F VTAG+FLY++LV+MLP +
Sbjct: 445 LLLLSLVSGALGLGGAVLGVGLSLGPVPLTPWVFGVTAGVFLYVALVDMLPALLRPPEPL 504
Query: 624 PWMMFLLQNFGLILGWLSLLLLAIYEQNI 652
P LLQ GL+LG +L + + E+ +
Sbjct: 505 PTPHVLLQGLGLLLGGGLMLAITLLEERL 533
>gi|206597539 solute carrier family 39 (metal ion transporter),
member 5 [Homo sapiens]
Length = 540
Score = 162 bits (411), Expect = 7e-40
Identities = 126/389 (32%), Positives = 186/389 (47%), Gaps = 53/389 (13%)
Query: 307 DQTCFSARQLVEIFLQKGLSLISKEDFKQMSPGIIQQLLSCSCHLPKDQQAKLPP-TTLE 365
++ C + QL+ F + ++ F + P ++ Q+ S C A PP L
Sbjct: 155 NEDCLNGSQLLVNFGLSPAAPLTPRQFALLCPALLYQIDSRVCI---GAPAPAPPGDLLS 211
Query: 366 KYGYSTVAVTLLTLGSMLGTALVLFHSCEENYRLILQLFVGLAVGTLSGDALLHLIPQVL 425
S +AV LL+L S L L+ R +L LAVGTL GDALLHL+P
Sbjct: 212 ALLQSALAVLLLSLPSPLSLLLLRLLG-PRLLRPLLGFLGALAVGTLCGDALLHLLP--- 267
Query: 426 GLHKQEAPEFGHFHESKGHIWKLMGLIGGIHGFFLIEKCFILL----VSPNDKK------ 475
H QE G + + + ++GG+ F++E LL + P +
Sbjct: 268 --HAQEGRHAGPGGLPEKDLGPGLSVLGGLFLLFVLENMLGLLRHRGLRPRCCRRKRRNL 325
Query: 476 -----SPEDS--------QAAEMPIGSMTASNRKCKAISLLAI----------------- 505
PE+ QAA P G+ + + LA
Sbjct: 326 ETRNLDPENGSGMALQPLQAAPEP-GAQGQREKNSQHPPALAPPGHQGHSHGHQGGTDIT 384
Query: 506 -MILVGDSLHNFADGLAIGAAFSSSSESGVTTTIAILCHEIPHEMGDFAVLLSSGLSMKT 564
M+L+GD LHN DGLAIGAAFS SG++TT+A+ CHE+PHE+GDFA+LL SGLS +
Sbjct: 385 WMVLLGDGLHNLTDGLAIGAAFSDGFSSGLSTTLAVFCHELPHELGDFAMLLQSGLSFRR 444
Query: 565 AILMNFISSLTAFMGLYIGLSVSADPC-VQDWIFTVTAGMFLYLSLVEMLPEMTHVQTQR 623
+L++ +S G +G+ +S P + W+F VTAG+FLY++LV+MLP +
Sbjct: 445 LLLLSLVSGALGLGGAVLGVGLSLGPVPLTPWVFGVTAGVFLYVALVDMLPALLRPPEPL 504
Query: 624 PWMMFLLQNFGLILGWLSLLLLAIYEQNI 652
P LLQ GL+LG +L + + E+ +
Sbjct: 505 PTPHVLLQGLGLLLGGGLMLAITLLEERL 533
>gi|187936949 solute carrier family 39 (zinc transporter), member 10
[Homo sapiens]
Length = 831
Score = 161 bits (408), Expect = 2e-39
Identities = 80/169 (47%), Positives = 119/169 (70%), Gaps = 7/169 (4%)
Query: 491 TASNRKCKAISLLAIMILVGDSLHNFADGLAIGAAFSSSSESGVTTTIAILCHEIPHEMG 550
+ S+ K I+ +A M+++GD +HNF+DGLAIGAAFS+ G++T+IA+ CHE+PHE+G
Sbjct: 657 SGSDLKETGIANIAWMVIMGDGIHNFSDGLAIGAAFSAGLTGGISTSIAVFCHELPHELG 716
Query: 551 DFAVLLSSGLSMKTAILMNFISSLTAFMGLYIGLSVSA-DPCVQDWIFTVTAGMFLYLSL 609
DFAVLL +G+++K AI+ N +S++ A++G+ IG +V + WIF VTAGMFLY++L
Sbjct: 717 DFAVLLKAGMTVKQAIVYNLLSAMMAYIGMLIGTAVGQYANNITLWIFAVTAGMFLYVAL 776
Query: 610 VEMLPEMTHVQTQR------PWMMFLLQNFGLILGWLSLLLLAIYEQNI 652
V+MLPEM H P F+LQN GL+ G+ +L++A+YE I
Sbjct: 777 VDMLPEMLHGDGDNEEHGFCPVGQFILQNLGLLFGFAIMLVIALYEDKI 825
Score = 68.9 bits (167), Expect = 1e-11
Identities = 57/181 (31%), Positives = 86/181 (47%), Gaps = 29/181 (16%)
Query: 310 CFSARQLVEIFLQKGLSLISKEDFKQMSPGIIQQLLSCSC--HLPK------DQQAKLPP 361
C + QL++ + S IS + F + P ++ Q+ S C H K ++ L P
Sbjct: 337 CLNVTQLLKYYGHGANSPISTDLFTYLCPALLYQIDSRLCIEHFDKLLVEDINKDKNLVP 396
Query: 362 TTLEKYGYST-----VAVTLLTLGSMLGTALV--LFHSCEENYRLILQLFVGLAVGTLSG 414
G S +++T+++L S+LG LV + C ++ +L V LAVGT+SG
Sbjct: 397 EDEANIGASAWICGIISITVISLLSLLGVILVPIINQGC---FKFLLTFLVALAVGTMSG 453
Query: 415 DALLHLIPQVLGLH---KQEAPEFGHFH--------ESKGHIWKLMGLIGGIHGFFLIEK 463
DALLHL+P G H Q A GH H E + K + +GGI+ F+IE
Sbjct: 454 DALLHLLPHSQGGHDHSHQHAHGHGHSHGHESNKFLEEYDAVLKGLVALGGIYLLFIIEH 513
Query: 464 C 464
C
Sbjct: 514 C 514
>gi|55741750 solute carrier family 39 (zinc transporter), member 10
[Homo sapiens]
Length = 831
Score = 161 bits (408), Expect = 2e-39
Identities = 80/169 (47%), Positives = 119/169 (70%), Gaps = 7/169 (4%)
Query: 491 TASNRKCKAISLLAIMILVGDSLHNFADGLAIGAAFSSSSESGVTTTIAILCHEIPHEMG 550
+ S+ K I+ +A M+++GD +HNF+DGLAIGAAFS+ G++T+IA+ CHE+PHE+G
Sbjct: 657 SGSDLKETGIANIAWMVIMGDGIHNFSDGLAIGAAFSAGLTGGISTSIAVFCHELPHELG 716
Query: 551 DFAVLLSSGLSMKTAILMNFISSLTAFMGLYIGLSVSA-DPCVQDWIFTVTAGMFLYLSL 609
DFAVLL +G+++K AI+ N +S++ A++G+ IG +V + WIF VTAGMFLY++L
Sbjct: 717 DFAVLLKAGMTVKQAIVYNLLSAMMAYIGMLIGTAVGQYANNITLWIFAVTAGMFLYVAL 776
Query: 610 VEMLPEMTHVQTQR------PWMMFLLQNFGLILGWLSLLLLAIYEQNI 652
V+MLPEM H P F+LQN GL+ G+ +L++A+YE I
Sbjct: 777 VDMLPEMLHGDGDNEEHGFCPVGQFILQNLGLLFGFAIMLVIALYEDKI 825
Score = 68.9 bits (167), Expect = 1e-11
Identities = 57/181 (31%), Positives = 86/181 (47%), Gaps = 29/181 (16%)
Query: 310 CFSARQLVEIFLQKGLSLISKEDFKQMSPGIIQQLLSCSC--HLPK------DQQAKLPP 361
C + QL++ + S IS + F + P ++ Q+ S C H K ++ L P
Sbjct: 337 CLNVTQLLKYYGHGANSPISTDLFTYLCPALLYQIDSRLCIEHFDKLLVEDINKDKNLVP 396
Query: 362 TTLEKYGYST-----VAVTLLTLGSMLGTALV--LFHSCEENYRLILQLFVGLAVGTLSG 414
G S +++T+++L S+LG LV + C ++ +L V LAVGT+SG
Sbjct: 397 EDEANIGASAWICGIISITVISLLSLLGVILVPIINQGC---FKFLLTFLVALAVGTMSG 453
Query: 415 DALLHLIPQVLGLH---KQEAPEFGHFH--------ESKGHIWKLMGLIGGIHGFFLIEK 463
DALLHL+P G H Q A GH H E + K + +GGI+ F+IE
Sbjct: 454 DALLHLLPHSQGGHDHSHQHAHGHGHSHGHESNKFLEEYDAVLKGLVALGGIYLLFIIEH 513
Query: 464 C 464
C
Sbjct: 514 C 514
>gi|205830405 solute carrier family 39 (zinc transporter), member 8
isoform b [Homo sapiens]
Length = 444
Score = 157 bits (397), Expect = 3e-38
Identities = 112/375 (29%), Positives = 180/375 (48%), Gaps = 68/375 (18%)
Query: 300 EDGPVSWDQTCFSARQLVEIFLQKGLSLISKEDFKQMSPGIIQQLLSCSCH-LPKDQQAK 358
E G + ++Q C +A ++ + + I+ F + P ++QQL C PK K
Sbjct: 65 EPGQLHFNQ-CLTAEEIFSLHGFSNATQITSSKFSVICPAVLQQLNFHPCEDRPKH---K 120
Query: 359 LPPTTLEKYGYSTVAVTLLTLGSMLGTALVLFHSCEENY-RLILQLFVGLAVGTLSGDAL 417
P+ E +GY ++VT++ L S+LG L+L +++Y IL FVGLA+GTL +A+
Sbjct: 121 TRPSHSEVWGYGFLSVTIINLASLLG--LILTPLIKKSYFPKILTFFVGLAIGTLFSNAI 178
Query: 418 LHLIPQVLGLHKQEAPEFGHFHESKGHIWKLMGLIGGIHGFFLIEKCFILLVSP------ 471
LIP+ FG + ++ K + + GG + F E+ +L+
Sbjct: 179 FQLIPEA----------FGFDPKVDSYVEKAVAVFGGFYLLFFFERMLKMLLKTYGQNGH 228
Query: 472 ----NDKKSPEDS---------------------------------------QAAEMPIG 488
ND P++ + P
Sbjct: 229 THFGNDNFGPQEKTHQPKALPAINGVTCYANPAVTEANGHIHFDNVSVVSLQDGKKEPSS 288
Query: 489 SMTASNRKCKAISLLAIMILVGDSLHNFADGLAIGAAFSSSSESGVTTTIAILCHEIPHE 548
K I +A MI + D+LHNF DGLAIGA+ + S G++T+IAILC E PHE
Sbjct: 289 CTCLKGPKLSEIGTIAWMITLCDALHNFIDGLAIGASCTLSLLQGLSTSIAILCEEFPHE 348
Query: 549 MGDFAVLLSSGLSMKTAILMNFISSLTAFMGLYIGLSVSADPCVQDWIFTVTAGMFLYLS 608
+GDF +LL++G+S + A+L NF+S+ + ++GL G+ V + + IF + GMFLY+S
Sbjct: 349 LGDFVILLNAGMSTRQALLFNFLSACSCYVGLAFGILV-GNNFAPNIIFALAGGMFLYIS 407
Query: 609 LVEMLPEMTHVQTQR 623
L +M PEM + ++
Sbjct: 408 LADMFPEMNDMLREK 422
>gi|153252201 solute carrier family 39 (zinc transporter), member 6
isoform 1 [Homo sapiens]
Length = 755
Score = 156 bits (394), Expect = 6e-38
Identities = 74/162 (45%), Positives = 115/162 (70%), Gaps = 5/162 (3%)
Query: 496 KCKAISLLAIMILVGDSLHNFADGLAIGAAFSSSSESGVTTTIAILCHEIPHEMGDFAVL 555
K ++ LA M+++GD LHNF+DGLAIGAAF+ SG++T++A+ CHE+PHE+GDFAVL
Sbjct: 588 KDAGVATLAWMVIMGDGLHNFSDGLAIGAAFTEGLSSGLSTSVAVFCHELPHELGDFAVL 647
Query: 556 LSSGLSMKTAILMNFISSLTAFMGLYIGLSVS-ADPCVQDWIFTVTAGMFLYLSLVEMLP 614
L +G+++K A+L N +S++ A++G+ G+ + V WIF +TAG+F+Y++LV+M+P
Sbjct: 648 LKAGMTVKQAVLYNALSAMLAYLGMATGIFIGHYAENVSMWIFALTAGLFMYVALVDMVP 707
Query: 615 EMTHVQTQ----RPWMMFLLQNFGLILGWLSLLLLAIYEQNI 652
EM H W F LQN G++LG+ +LL++I+E I
Sbjct: 708 EMLHNDASDHGCSRWGYFFLQNAGMLLGFGIMLLISIFEHKI 749
Score = 71.2 bits (173), Expect = 3e-12
Identities = 57/209 (27%), Positives = 96/209 (45%), Gaps = 35/209 (16%)
Query: 308 QTCFSARQLVEIFLQKGLSL---ISKEDFKQMSPGIIQQLLSCSCHL-PKDQQAKLPPTT 363
Q CF+A +L+ G+ + ++ +F + P II Q+ + SC + +++A++PP T
Sbjct: 262 QECFNASKLLT---SHGMGIQVPLNATEFNYLCPAIINQIDARSCLIHTSEKKAEIPPKT 318
Query: 364 LE---KYGYSTVAVTLLTLGSMLGTALVLFHSCEENYRLILQLFVGLAVGTLSGDALLHL 420
+ +A+++++ S+LG LV + ++ +L V LAVGTLSGDA LHL
Sbjct: 319 YSLQIAWVGGFIAISIISFLSLLGVILVPLMN-RVFFKFLLSFLVALAVGTLSGDAFLHL 377
Query: 421 IPQVLGLH------------KQEAPEFGHFHESK-------GHIWKLMGLIGGIHGFFLI 461
+P H + P F H WK + +GG++ FL+
Sbjct: 378 LPHSHASHHHSHSHEEPAMEMKRGPLFSHLSSQNIEESAYFDSTWKGLTALGGLYFMFLV 437
Query: 462 EKCFILLVSPNDK-----KSPEDSQAAEM 485
E L+ DK K PE+ E+
Sbjct: 438 EHVLTLIKQFKDKKKKNQKKPENDDDVEI 466
>gi|153252214 solute carrier family 39 (zinc transporter), member 6
isoform 2 [Homo sapiens]
Length = 433
Score = 128 bits (321), Expect = 2e-29
Identities = 57/119 (47%), Positives = 91/119 (76%), Gaps = 1/119 (0%)
Query: 496 KCKAISLLAIMILVGDSLHNFADGLAIGAAFSSSSESGVTTTIAILCHEIPHEMGDFAVL 555
K ++ LA M+++GD LHNF+DGLAIGAAF+ SG++T++A+ CHE+PHE+GDFAVL
Sbjct: 313 KDAGVATLAWMVIMGDGLHNFSDGLAIGAAFTEGLSSGLSTSVAVFCHELPHELGDFAVL 372
Query: 556 LSSGLSMKTAILMNFISSLTAFMGLYIGLSVS-ADPCVQDWIFTVTAGMFLYLSLVEML 613
L +G+++K A+L N +S++ A++G+ G+ + V WIF +TAG+F+Y++LV+M+
Sbjct: 373 LKAGMTVKQAVLYNALSAMLAYLGMATGIFIGHYAENVSMWIFALTAGLFMYVALVDMV 431
Score = 67.8 bits (164), Expect = 3e-11
Identities = 51/186 (27%), Positives = 85/186 (45%), Gaps = 29/186 (15%)
Query: 328 ISKEDFKQMSPGIIQQLLSCSCHL-PKDQQAKLPPTTLE---KYGYSTVAVTLLTLGSML 383
++ +F + P II Q+ + SC + +++A++PP T + +A+++++ S+L
Sbjct: 7 LNATEFNYLCPAIINQIDARSCLIHTSEKKAEIPPKTYSLQIAWVGGFIAISIISFLSLL 66
Query: 384 GTALVLFHSCEENYRLILQLFVGLAVGTLSGDALLHLIPQVLGLH------------KQE 431
G LV + ++ +L V LAVGTLSGDA LHL+P H +
Sbjct: 67 GVILVPLMN-RVFFKFLLSFLVALAVGTLSGDAFLHLLPHSHASHHHSHSHEEPAMEMKR 125
Query: 432 APEFGHFHESK-------GHIWKLMGLIGGIHGFFLIEKCFILLVSPNDK-----KSPED 479
P F H WK + +GG++ FL+E L+ DK K PE+
Sbjct: 126 GPLFSHLSSQNIEESAYFDSTWKGLTALGGLYFMFLVEHVLTLIKQFKDKKKKNQKKPEN 185
Query: 480 SQAAEM 485
E+
Sbjct: 186 DDDVEI 191
>gi|117553619 solute carrier family 39, member 7 [Homo sapiens]
Length = 469
Score = 127 bits (318), Expect = 4e-29
Identities = 97/339 (28%), Positives = 151/339 (44%), Gaps = 60/339 (17%)
Query: 367 YGYSTVAVTLLTLGSMLGTALVLFHSCEENYRLILQLFVGLAVGTLSGDALLHLIPQVLG 426
+ Y+ A L++ L+ S +R +LQ+ + A G L GDA LHLIP L
Sbjct: 135 WAYALGATVLISAAPFFVLFLIPVESNSPRHRSLLQILLSFASGGLLGDAFLHLIPHALE 194
Query: 427 LHKQ---EAPEFGHFHESKGHIWKL-MGLIGGIHGFFLIEKCFILLV------------- 469
H E P GH H +G I + + ++ GI F ++EK F+ V
Sbjct: 195 PHSHHTLEQPGHGHSHSGQGPILSVGLWVLSGIVAFLVVEK-FVRHVKGGHGHSHGHGHA 253
Query: 470 ---------------SPNDKKSPEDSQAA---------------EMPIGSMTASNRKCKA 499
S +K+S E+ + + P+ A K
Sbjct: 254 HSHTRGSHGHGRQERSTKEKQSSEEEEKETRGVQKRRGGSTVPKDGPVRPQNAEEEKRGL 313
Query: 500 -ISLLAIMILVGDSLHNFADGLAIGAAFSSSSESGVTTTIAILCHEIPHEMGDFAVLLSS 558
+ + + L D HNF DGLAIGA+F G+ TT+ +L HE+PHE+GDFA+L+ S
Sbjct: 314 DLRVSGYLNLAADLAHNFTDGLAIGASFRGGRGLGILTTMTVLLHEVPHEVGDFAILVQS 373
Query: 559 GLSMKTAILMNFISSLTAFMGLYIGL--------SVSADPCVQDWIFTVTAGMFLYLSLV 610
G S K A+ + ++++ A G L S A W+ TAG F+Y++ V
Sbjct: 374 GCSKKQAMRLQLLTAVGALAGTACALLTEGGAVGSEIAGGAGPGWVLPFTAGGFIYVATV 433
Query: 611 EMLPEMTHVQTQRPWMMFLLQNFGLILGWLSLLLLAIYE 649
+LPE+ + + LL+ GL+ G + ++L+A E
Sbjct: 434 SVLPELLREASP---LQSLLEVLGLLGGVIMMVLIAHLE 469
>gi|117553608 solute carrier family 39, member 7 [Homo sapiens]
Length = 469
Score = 127 bits (318), Expect = 4e-29
Identities = 97/339 (28%), Positives = 151/339 (44%), Gaps = 60/339 (17%)
Query: 367 YGYSTVAVTLLTLGSMLGTALVLFHSCEENYRLILQLFVGLAVGTLSGDALLHLIPQVLG 426
+ Y+ A L++ L+ S +R +LQ+ + A G L GDA LHLIP L
Sbjct: 135 WAYALGATVLISAAPFFVLFLIPVESNSPRHRSLLQILLSFASGGLLGDAFLHLIPHALE 194
Query: 427 LHKQ---EAPEFGHFHESKGHIWKL-MGLIGGIHGFFLIEKCFILLV------------- 469
H E P GH H +G I + + ++ GI F ++EK F+ V
Sbjct: 195 PHSHHTLEQPGHGHSHSGQGPILSVGLWVLSGIVAFLVVEK-FVRHVKGGHGHSHGHGHA 253
Query: 470 ---------------SPNDKKSPEDSQAA---------------EMPIGSMTASNRKCKA 499
S +K+S E+ + + P+ A K
Sbjct: 254 HSHTRGSHGHGRQERSTKEKQSSEEEEKETRGVQKRRGGSTVPKDGPVRPQNAEEEKRGL 313
Query: 500 -ISLLAIMILVGDSLHNFADGLAIGAAFSSSSESGVTTTIAILCHEIPHEMGDFAVLLSS 558
+ + + L D HNF DGLAIGA+F G+ TT+ +L HE+PHE+GDFA+L+ S
Sbjct: 314 DLRVSGYLNLAADLAHNFTDGLAIGASFRGGRGLGILTTMTVLLHEVPHEVGDFAILVQS 373
Query: 559 GLSMKTAILMNFISSLTAFMGLYIGL--------SVSADPCVQDWIFTVTAGMFLYLSLV 610
G S K A+ + ++++ A G L S A W+ TAG F+Y++ V
Sbjct: 374 GCSKKQAMRLQLLTAVGALAGTACALLTEGGAVGSEIAGGAGPGWVLPFTAGGFIYVATV 433
Query: 611 EMLPEMTHVQTQRPWMMFLLQNFGLILGWLSLLLLAIYE 649
+LPE+ + + LL+ GL+ G + ++L+A E
Sbjct: 434 SVLPELLREASP---LQSLLEVLGLLGGVIMMVLIAHLE 469
>gi|40255101 solute carrier family 39 (zinc transporter), member 13
isoform b [Homo sapiens]
Length = 364
Score = 103 bits (258), Expect = 4e-22
Identities = 77/268 (28%), Positives = 134/268 (50%), Gaps = 31/268 (11%)
Query: 401 LQLFVGLAVGTLSGDALLHLIPQVLGLHKQEAPEFGHFHESKGHIWKL-MGLIGGIHGFF 459
L+ + A+G L G+ LHL+P+ +P G +S +L + +I GI F
Sbjct: 106 LKQLLSFALGGLLGNVFLHLLPEAWAYTCSASP--GGEGQSLQQQQQLGLWVIAGILTFL 163
Query: 460 LIEKCFILLVSPNDKKSPEDSQ----------------AAEMPIGSMTASNRKCKAISLL 503
+EK F+ ++P AAE +G++ S + ++LL
Sbjct: 164 ALEKMFLDSKEEGTSQAPNKDPTAAAAALNGGHCLAQPAAEPGLGAVVRSIKVSGYLNLL 223
Query: 504 AIMILVGDSLHNFADGLAIGAAFSSSSESGVTTTIAILCHEIPHEMGDFAVLLSSGLSMK 563
A +++ NF GLA+ A+F S + G+ TT+AIL HEIPHE+GDFA+LL +G
Sbjct: 224 A------NTIDNFTHGLAVAASFLVSKKIGLLTTMAILLHEIPHEVGDFAILLRAGFDRW 277
Query: 564 TAILMNFISSLTAFMGLYIGLSVSADPCVQD---WIFTVTAGMFLYLSLVEMLPEMTHVQ 620
+A + ++L +G + + V++ W+ T+G FLY++LV +LP++ ++
Sbjct: 278 SAAKLQLSTALGGLLGAGFAICTQSPKGVEETAAWVLPFTSGGFLYIALVNVLPDL--LE 335
Query: 621 TQRPWMMFLLQNFGLILGWLSLLLLAIY 648
+ PW L Q L G + ++L +++
Sbjct: 336 EEDPWRS-LQQLLLLCAGIVVMVLFSLF 362
>gi|190014617 solute carrier family 39 (zinc transporter), member 13
isoform a [Homo sapiens]
Length = 371
Score = 101 bits (251), Expect = 2e-21
Identities = 78/275 (28%), Positives = 134/275 (48%), Gaps = 38/275 (13%)
Query: 401 LQLFVGLAVGTLSGDALLHLIPQVLGLHKQEAPEFGHFHESKGHIWKL-MGLIGGIHGFF 459
L+ + A+G L G+ LHL+P+ +P G +S +L + +I GI F
Sbjct: 106 LKQLLSFALGGLLGNVFLHLLPEAWAYTCSASP--GGEGQSLQQQQQLGLWVIAGILTFL 163
Query: 460 LIEKCFILLVSPNDKKSPEDSQ----------------AAEMPIGSMTASNRKCKAISLL 503
+EK F+ ++P AAE +G++ S + ++LL
Sbjct: 164 ALEKMFLDSKEEGTSQAPNKDPTAAAAALNGGHCLAQPAAEPGLGAVVRSIKVSGYLNLL 223
Query: 504 AIMILVGDSLHNFADGLAIGAAFSSSSESGVTTTIAILCHEIPHEMGDFAVLLSSGLSMK 563
A +++ NF GLA+ A+F S + G+ TT+AIL HEIPHE+GDFA+LL +G
Sbjct: 224 A------NTIDNFTHGLAVAASFLVSKKIGLLTTMAILLHEIPHEVGDFAILLRAGFDRW 277
Query: 564 TAILMNFISSLTAFMGLYIGLS-------VSADPCVQD---WIFTVTAGMFLYLSLVEML 613
+A + ++L +G + V P ++ W+ T+G FLY++LV +L
Sbjct: 278 SAAKLQLSTALGGLLGAGFAICTQSPKGVVGCSPAAEETAAWVLPFTSGGFLYIALVNVL 337
Query: 614 PEMTHVQTQRPWMMFLLQNFGLILGWLSLLLLAIY 648
P++ ++ + PW L Q L G + ++L +++
Sbjct: 338 PDL--LEEEDPWRS-LQQLLLLCAGIVVMVLFSLF 369
>gi|40254928 solute carrier family 39 (zinc transporter), member 9
[Homo sapiens]
Length = 307
Score = 58.9 bits (141), Expect = 1e-08
Identities = 83/323 (25%), Positives = 143/323 (44%), Gaps = 63/323 (19%)
Query: 372 VAVTLLTLGSMLGTALVLFHSCEENY-RLILQLFVGLAVGTLSGDALLHLIPQVL----- 425
++++LL+L ++G + N+ L+L L G L G AL ++P+ +
Sbjct: 5 ISISLLSLAMLVGCYVAGIIPLAVNFSEERLKLVTVLGAGLLCGTALAVIVPEGVHALYE 64
Query: 426 ----GLHKQEAPEFG-------------HFHESKGHIWKLMGLIGG--IHGFFLIEKCFI 466
G H Q + H HE +L IG + GF F+
Sbjct: 65 DILEGKHHQASETHNVIASDKAAEKSVVHEHEHSHDHTQLHAYIGVSLVLGFV-----FM 119
Query: 467 LLVSP---NDKKSPEDSQAAEMPIGSMTASNRKCKAISLLAIMILVGDSLHNFADGLAIG 523
LLV + S +D +AA +SN K I +G +H ADG+A+G
Sbjct: 120 LLVDQIGNSHVHSTDDPEAAR-------SSNSK--------ITTTLGLVVHAAADGVALG 164
Query: 524 AAFSSSSES-GVTTTIAILCHEIPHEMGDFAVLLSSGLS---MKTAILMNFISSLTAFMG 579
AA S+S S + +AI+ H+ P G + L+ +GL ++ +L+ +++ M
Sbjct: 165 AAASTSQTSVQLIVFVAIMLHKAPAAFGLVSFLMHAGLERNRIRKHLLVFALAAPVMSMV 224
Query: 580 LYIGLSVSADPCVQDWIFT-----VTAGMFLYLSLVEMLPEMTHV-QTQRPWM-----MF 628
Y+GLS S+ + + T +AG FLY++ V +LPE+ + + +P +
Sbjct: 225 TYLGLSKSSKEALSEVNATGVAMLFSAGTFLYVATVHVLPEVGGIGHSHKPDATGGRGLS 284
Query: 629 LLQNFGLILGWLSLLLLAIYEQN 651
L+ L+LG L L+L++ Q+
Sbjct: 285 RLEVAALVLGCLIPLILSVGHQH 307
>gi|156415986 solute carrier family 39 (zinc transporter), member 2
[Homo sapiens]
Length = 309
Score = 45.8 bits (107), Expect = 1e-04
Identities = 34/119 (28%), Positives = 61/119 (51%), Gaps = 8/119 (6%)
Query: 502 LLAIMILVGDSLHNFADGLAIGAAFSSSSESGVTTTIAILCHEIPHEMGDFAVLLSSGLS 561
L A+++L+ S H+ +GLA+G + + V +A+L H+ G L+ G S
Sbjct: 163 LRALVLLLSLSFHSVFEGLAVG--LQPTVAATVQLCLAVLAHKGLVVFGVGMRLVHLGTS 220
Query: 562 MKTAILMNFISSLTAFMGLYIGLSVSADPC------VQDWIFTVTAGMFLYLSLVEMLP 614
+ A+ + +L + +GL +GL+V+ Q + V AG FLY++ +E+LP
Sbjct: 221 SRWAVFSILLLALMSPLGLAVGLAVTGGDSEGGRGLAQAVLEGVAAGTFLYVTFLEILP 279
>gi|21361423 solute carrier family 39 (zinc transporter), member 1
[Homo sapiens]
Length = 324
Score = 42.0 bits (97), Expect = 0.002
Identities = 47/204 (23%), Positives = 86/204 (42%), Gaps = 22/204 (10%)
Query: 457 GFFLIEKCFILLVSPNDKKSPEDSQAAEMPIGSMT--------------ASNRKCKAISL 502
GFFL+ + ++ ++ P + +G++ AS +L
Sbjct: 119 GFFLVLVMEQITLAYKEQSGPSPLEETRALLGTVNGGPQHWHDGPGVPQASGAPATPSAL 178
Query: 503 LAIMILVGDSLHNFADGLAIGAAFSSSSESGVTTTIAILCHEIPHEMGDFAVLLSSGLSM 562
A +++ +LH+ +GLA+G + +A+L H+ + LL S L
Sbjct: 179 RACVLVFSLALHSVFEGLAVG--LQRDRARAMELCLALLLHKGILAVSLSLRLLQSHLRA 236
Query: 563 KTAILMNFISSLTAFMGLYIG--LSVSADPC---VQDWIFTVTAGMFLYLSLVEMLPEMT 617
+ + S +G+ +G L+ SA P Q + + AG FLY++ +E+LP+
Sbjct: 237 QVVAGCGILFSCMTPLGIGLGAALAESAGPLHQLAQSVLEGMAAGTFLYITFLEILPQEL 296
Query: 618 HVQTQRPW-MMFLLQNFGLILGWL 640
QR ++ LL F L+ G L
Sbjct: 297 ASSEQRILKVILLLAGFALLTGLL 320
>gi|229577422 solute carrier family 39, member 11 isoform 1 [Homo
sapiens]
Length = 342
Score = 34.3 bits (77), Expect = 0.37
Identities = 25/118 (21%), Positives = 50/118 (42%), Gaps = 8/118 (6%)
Query: 506 MILVGDSLHNFADGLAIGAAF-------SSSSESGVTTTIAILCHEIPHEMGDFAVLLSS 558
++++ ++HN +GLA+G F S++ ES I I P + L +
Sbjct: 196 LLILAITIHNVPEGLAVGVGFGAIEKTASATFESARNLAIGIGIQNFPEGLAVSLPLRGA 255
Query: 559 GLSMKTAILMNFISSLT-AFMGLYIGLSVSADPCVQDWIFTVTAGMFLYLSLVEMLPE 615
G S A +S + G++ +V + + AG +Y+ + +++PE
Sbjct: 256 GFSTWRAFWYGQLSGMVEPLAGVFGAFAVVLAEPILPYALAFAAGAMVYVVMDDIIPE 313
>gi|229577418 solute carrier family 39, member 11 isoform 2 [Homo
sapiens]
Length = 335
Score = 34.3 bits (77), Expect = 0.37
Identities = 25/118 (21%), Positives = 50/118 (42%), Gaps = 8/118 (6%)
Query: 506 MILVGDSLHNFADGLAIGAAF-------SSSSESGVTTTIAILCHEIPHEMGDFAVLLSS 558
++++ ++HN +GLA+G F S++ ES I I P + L +
Sbjct: 189 LLILAITIHNVPEGLAVGVGFGAIEKTASATFESARNLAIGIGIQNFPEGLAVSLPLRGA 248
Query: 559 GLSMKTAILMNFISSLT-AFMGLYIGLSVSADPCVQDWIFTVTAGMFLYLSLVEMLPE 615
G S A +S + G++ +V + + AG +Y+ + +++PE
Sbjct: 249 GFSTWRAFWYGQLSGMVEPLAGVFGAFAVVLAEPILPYALAFAAGAMVYVVMDDIIPE 306
>gi|205360987 TBP-associated factor 1B [Homo sapiens]
Length = 588
Score = 32.3 bits (72), Expect = 1.4
Identities = 29/118 (24%), Positives = 47/118 (39%), Gaps = 23/118 (19%)
Query: 276 RKQNNIITHDQDYSNFSSSMEKESEDGPVSW---------DQTCFSARQLVEIFLQKGLS 326
+K+ ++ + +S S + P S+ D+TCF L + +KG S
Sbjct: 445 KKREMVVNLQKQFSTLVESTATAGKKSPSSFQFNWTEEDTDRTCFHGHSLQGVLKEKGQS 504
Query: 327 LISKEDFKQMSPGIIQQLLSCSC-HLPKDQQAKLPPTTLEKYGYSTVAVTLLTLGSML 383
L++K +S Q+ C C H+ TT E+ YS +L L S L
Sbjct: 505 LLTKNSLYWLS---TQKFCRCYCTHV----------TTYEESNYSLSYQFILNLFSFL 549
>gi|168480072 BCL2-related protein A1 isoform 2 [Homo sapiens]
Length = 163
Score = 32.0 bits (71), Expect = 1.8
Identities = 20/61 (32%), Positives = 35/61 (57%), Gaps = 8/61 (13%)
Query: 280 NIITHDQDYSNFSSSMEKESEDGPVSWDQTCFSARQLVEIFLQKGLSLISKEDFKQMSPG 339
N+++ D + F+ MEKE EDG ++W ++V IF +G+ LI K +Q++P
Sbjct: 60 NVVSVDTARTLFNQVMEKEFEDGIINWG-------RIVTIFAFEGI-LIKKLLRQQIAPD 111
Query: 340 I 340
+
Sbjct: 112 V 112
>gi|4757840 BCL2-related protein A1 isoform 1 [Homo sapiens]
Length = 175
Score = 32.0 bits (71), Expect = 1.8
Identities = 20/61 (32%), Positives = 35/61 (57%), Gaps = 8/61 (13%)
Query: 280 NIITHDQDYSNFSSSMEKESEDGPVSWDQTCFSARQLVEIFLQKGLSLISKEDFKQMSPG 339
N+++ D + F+ MEKE EDG ++W ++V IF +G+ LI K +Q++P
Sbjct: 60 NVVSVDTARTLFNQVMEKEFEDGIINWG-------RIVTIFAFEGI-LIKKLLRQQIAPD 111
Query: 340 I 340
+
Sbjct: 112 V 112
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.135 0.396
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,778,194
Number of Sequences: 37866
Number of extensions: 1025486
Number of successful extensions: 2776
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 25
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 2659
Number of HSP's gapped (non-prelim): 62
length of query: 654
length of database: 18,247,518
effective HSP length: 109
effective length of query: 545
effective length of database: 14,120,124
effective search space: 7695467580
effective search space used: 7695467580
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.