BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|223633937 solute carrier family 39 (zinc transporter), member 12 isoform 2 [Homo sapiens] (654 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|223633937 solute carrier family 39 (zinc transporter), member... 1300 0.0 gi|223633939 solute carrier family 39 (zinc transporter), member... 1282 0.0 gi|115430255 solute carrier family 39 (zinc transporter), member... 275 1e-73 gi|115430259 solute carrier family 39 (zinc transporter), member... 271 2e-72 gi|205830424 solute carrier family 39 (zinc transporter), member... 186 8e-47 gi|190360568 solute carrier family 39 (zinc transporter), member... 186 8e-47 gi|190358541 solute carrier family 39 (zinc transporter), member... 180 3e-45 gi|24586665 solute carrier family 39 (zinc transporter), member ... 173 4e-43 gi|205830403 solute carrier family 39 (zinc transporter), member... 173 4e-43 gi|205830407 solute carrier family 39 (zinc transporter), member... 172 1e-42 gi|205830426 solute carrier family 39 (zinc transporter), member... 166 6e-41 gi|206597541 solute carrier family 39 (metal ion transporter), m... 162 7e-40 gi|206597539 solute carrier family 39 (metal ion transporter), m... 162 7e-40 gi|187936949 solute carrier family 39 (zinc transporter), member... 161 2e-39 gi|55741750 solute carrier family 39 (zinc transporter), member ... 161 2e-39 gi|205830405 solute carrier family 39 (zinc transporter), member... 157 3e-38 gi|153252201 solute carrier family 39 (zinc transporter), member... 156 6e-38 gi|153252214 solute carrier family 39 (zinc transporter), member... 128 2e-29 gi|117553619 solute carrier family 39, member 7 [Homo sapiens] 127 4e-29 gi|117553608 solute carrier family 39, member 7 [Homo sapiens] 127 4e-29 gi|40255101 solute carrier family 39 (zinc transporter), member ... 103 4e-22 gi|190014617 solute carrier family 39 (zinc transporter), member... 101 2e-21 gi|40254928 solute carrier family 39 (zinc transporter), member ... 59 1e-08 gi|156415986 solute carrier family 39 (zinc transporter), member... 46 1e-04 gi|21361423 solute carrier family 39 (zinc transporter), member ... 42 0.002 gi|229577422 solute carrier family 39, member 11 isoform 1 [Homo... 34 0.37 gi|229577418 solute carrier family 39, member 11 isoform 2 [Homo... 34 0.37 gi|205360987 TBP-associated factor 1B [Homo sapiens] 32 1.4 gi|168480072 BCL2-related protein A1 isoform 2 [Homo sapiens] 32 1.8 gi|4757840 BCL2-related protein A1 isoform 1 [Homo sapiens] 32 1.8 >gi|223633937 solute carrier family 39 (zinc transporter), member 12 isoform 2 [Homo sapiens] Length = 654 Score = 1300 bits (3365), Expect = 0.0 Identities = 654/654 (100%), Positives = 654/654 (100%) Query: 1 MCFRTKLSVSWVPLFLLLSRVFSTETDKPSAQDSRSRGSSGQPADLLQVLSAGDHPPHNH 60 MCFRTKLSVSWVPLFLLLSRVFSTETDKPSAQDSRSRGSSGQPADLLQVLSAGDHPPHNH Sbjct: 1 MCFRTKLSVSWVPLFLLLSRVFSTETDKPSAQDSRSRGSSGQPADLLQVLSAGDHPPHNH 60 Query: 61 SRSLIKTLLEKTGCPRRRNGMQGDCNLCFEPDALLLIAGGNFEDQLREEVVQRVSLLLLY 120 SRSLIKTLLEKTGCPRRRNGMQGDCNLCFEPDALLLIAGGNFEDQLREEVVQRVSLLLLY Sbjct: 61 SRSLIKTLLEKTGCPRRRNGMQGDCNLCFEPDALLLIAGGNFEDQLREEVVQRVSLLLLY 120 Query: 121 YIIHQEEICSSKLNMSNKEYKFYLHSLLSLRQDEDSSFLSQNETEDILAFTRQYFDTSQS 180 YIIHQEEICSSKLNMSNKEYKFYLHSLLSLRQDEDSSFLSQNETEDILAFTRQYFDTSQS Sbjct: 121 YIIHQEEICSSKLNMSNKEYKFYLHSLLSLRQDEDSSFLSQNETEDILAFTRQYFDTSQS 180 Query: 181 QCMETKTLQKKSGIVSSEGANESTLPQLAAMIITLSLQGVCLGQGNLPSPDYFTEYIFSS 240 QCMETKTLQKKSGIVSSEGANESTLPQLAAMIITLSLQGVCLGQGNLPSPDYFTEYIFSS Sbjct: 181 QCMETKTLQKKSGIVSSEGANESTLPQLAAMIITLSLQGVCLGQGNLPSPDYFTEYIFSS 240 Query: 241 LNRTNTLRLSELDQLLNTLWTRSTCIKNEKIHQFQRKQNNIITHDQDYSNFSSSMEKESE 300 LNRTNTLRLSELDQLLNTLWTRSTCIKNEKIHQFQRKQNNIITHDQDYSNFSSSMEKESE Sbjct: 241 LNRTNTLRLSELDQLLNTLWTRSTCIKNEKIHQFQRKQNNIITHDQDYSNFSSSMEKESE 300 Query: 301 DGPVSWDQTCFSARQLVEIFLQKGLSLISKEDFKQMSPGIIQQLLSCSCHLPKDQQAKLP 360 DGPVSWDQTCFSARQLVEIFLQKGLSLISKEDFKQMSPGIIQQLLSCSCHLPKDQQAKLP Sbjct: 301 DGPVSWDQTCFSARQLVEIFLQKGLSLISKEDFKQMSPGIIQQLLSCSCHLPKDQQAKLP 360 Query: 361 PTTLEKYGYSTVAVTLLTLGSMLGTALVLFHSCEENYRLILQLFVGLAVGTLSGDALLHL 420 PTTLEKYGYSTVAVTLLTLGSMLGTALVLFHSCEENYRLILQLFVGLAVGTLSGDALLHL Sbjct: 361 PTTLEKYGYSTVAVTLLTLGSMLGTALVLFHSCEENYRLILQLFVGLAVGTLSGDALLHL 420 Query: 421 IPQVLGLHKQEAPEFGHFHESKGHIWKLMGLIGGIHGFFLIEKCFILLVSPNDKKSPEDS 480 IPQVLGLHKQEAPEFGHFHESKGHIWKLMGLIGGIHGFFLIEKCFILLVSPNDKKSPEDS Sbjct: 421 IPQVLGLHKQEAPEFGHFHESKGHIWKLMGLIGGIHGFFLIEKCFILLVSPNDKKSPEDS 480 Query: 481 QAAEMPIGSMTASNRKCKAISLLAIMILVGDSLHNFADGLAIGAAFSSSSESGVTTTIAI 540 QAAEMPIGSMTASNRKCKAISLLAIMILVGDSLHNFADGLAIGAAFSSSSESGVTTTIAI Sbjct: 481 QAAEMPIGSMTASNRKCKAISLLAIMILVGDSLHNFADGLAIGAAFSSSSESGVTTTIAI 540 Query: 541 LCHEIPHEMGDFAVLLSSGLSMKTAILMNFISSLTAFMGLYIGLSVSADPCVQDWIFTVT 600 LCHEIPHEMGDFAVLLSSGLSMKTAILMNFISSLTAFMGLYIGLSVSADPCVQDWIFTVT Sbjct: 541 LCHEIPHEMGDFAVLLSSGLSMKTAILMNFISSLTAFMGLYIGLSVSADPCVQDWIFTVT 600 Query: 601 AGMFLYLSLVEMLPEMTHVQTQRPWMMFLLQNFGLILGWLSLLLLAIYEQNIKI 654 AGMFLYLSLVEMLPEMTHVQTQRPWMMFLLQNFGLILGWLSLLLLAIYEQNIKI Sbjct: 601 AGMFLYLSLVEMLPEMTHVQTQRPWMMFLLQNFGLILGWLSLLLLAIYEQNIKI 654 >gi|223633939 solute carrier family 39 (zinc transporter), member 12 isoform 1 [Homo sapiens] Length = 691 Score = 1282 bits (3317), Expect = 0.0 Identities = 654/691 (94%), Positives = 654/691 (94%), Gaps = 37/691 (5%) Query: 1 MCFRTKLSVSWVPLFLLLSRVFSTETDKPSAQDSRSRGSSGQPADLLQVLSAGDHPPHNH 60 MCFRTKLSVSWVPLFLLLSRVFSTETDKPSAQDSRSRGSSGQPADLLQVLSAGDHPPHNH Sbjct: 1 MCFRTKLSVSWVPLFLLLSRVFSTETDKPSAQDSRSRGSSGQPADLLQVLSAGDHPPHNH 60 Query: 61 SRSLIKTLLEKTGCPRRRNGMQGDCNLCFEPDALLLIAGGNFEDQLREEVVQRVSLLLLY 120 SRSLIKTLLEKTGCPRRRNGMQGDCNLCFEPDALLLIAGGNFEDQLREEVVQRVSLLLLY Sbjct: 61 SRSLIKTLLEKTGCPRRRNGMQGDCNLCFEPDALLLIAGGNFEDQLREEVVQRVSLLLLY 120 Query: 121 YIIHQEEICSSKLNMSNKEYKFYLHSLLSLRQDEDSSFLSQNETEDILAFTRQYFDTSQS 180 YIIHQEEICSSKLNMSNKEYKFYLHSLLSLRQDEDSSFLSQNETEDILAFTRQYFDTSQS Sbjct: 121 YIIHQEEICSSKLNMSNKEYKFYLHSLLSLRQDEDSSFLSQNETEDILAFTRQYFDTSQS 180 Query: 181 QCMETKTLQKKSGIVSSEGANESTLPQLAAMIITLSLQGVCLGQGNLPSPDYFTEYIFSS 240 QCMETKTLQKKSGIVSSEGANESTLPQLAAMIITLSLQGVCLGQGNLPSPDYFTEYIFSS Sbjct: 181 QCMETKTLQKKSGIVSSEGANESTLPQLAAMIITLSLQGVCLGQGNLPSPDYFTEYIFSS 240 Query: 241 LNRTNTLRLSELDQLLNTLWTRSTCIKNEKIHQFQRKQNNIITHDQDYSNFSSSMEKESE 300 LNRTNTLRLSELDQLLNTLWTRSTCIKNEKIHQFQRKQNNIITHDQDYSNFSSSMEKESE Sbjct: 241 LNRTNTLRLSELDQLLNTLWTRSTCIKNEKIHQFQRKQNNIITHDQDYSNFSSSMEKESE 300 Query: 301 DGPVSWDQTCFSARQLVEIFLQKGLSLISKEDFKQMSPGIIQQLLSCSCHLPKDQQAKLP 360 DGPVSWDQTCFSARQLVEIFLQKGLSLISKEDFKQMSPGIIQQLLSCSCHLPKDQQAKLP Sbjct: 301 DGPVSWDQTCFSARQLVEIFLQKGLSLISKEDFKQMSPGIIQQLLSCSCHLPKDQQAKLP 360 Query: 361 PTTLEKYGYSTVAVTLLTLGSMLGTALVLFHSCEENYRLILQLFVGLAVGTLSGDALLHL 420 PTTLEKYGYSTVAVTLLTLGSMLGTALVLFHSCEENYRLILQLFVGLAVGTLSGDALLHL Sbjct: 361 PTTLEKYGYSTVAVTLLTLGSMLGTALVLFHSCEENYRLILQLFVGLAVGTLSGDALLHL 420 Query: 421 IPQVLGLHKQEAPEFGHFHESKGHIWKLMGLIGGIHGFFLIEKCFILLVSPNDK------ 474 IPQVLGLHKQEAPEFGHFHESKGHIWKLMGLIGGIHGFFLIEKCFILLVSPNDK Sbjct: 421 IPQVLGLHKQEAPEFGHFHESKGHIWKLMGLIGGIHGFFLIEKCFILLVSPNDKQGLSLV 480 Query: 475 -------------------------------KSPEDSQAAEMPIGSMTASNRKCKAISLL 503 KSPEDSQAAEMPIGSMTASNRKCKAISLL Sbjct: 481 NGHVGHSHHLALNSELSDQAGRGKSASTIQLKSPEDSQAAEMPIGSMTASNRKCKAISLL 540 Query: 504 AIMILVGDSLHNFADGLAIGAAFSSSSESGVTTTIAILCHEIPHEMGDFAVLLSSGLSMK 563 AIMILVGDSLHNFADGLAIGAAFSSSSESGVTTTIAILCHEIPHEMGDFAVLLSSGLSMK Sbjct: 541 AIMILVGDSLHNFADGLAIGAAFSSSSESGVTTTIAILCHEIPHEMGDFAVLLSSGLSMK 600 Query: 564 TAILMNFISSLTAFMGLYIGLSVSADPCVQDWIFTVTAGMFLYLSLVEMLPEMTHVQTQR 623 TAILMNFISSLTAFMGLYIGLSVSADPCVQDWIFTVTAGMFLYLSLVEMLPEMTHVQTQR Sbjct: 601 TAILMNFISSLTAFMGLYIGLSVSADPCVQDWIFTVTAGMFLYLSLVEMLPEMTHVQTQR 660 Query: 624 PWMMFLLQNFGLILGWLSLLLLAIYEQNIKI 654 PWMMFLLQNFGLILGWLSLLLLAIYEQNIKI Sbjct: 661 PWMMFLLQNFGLILGWLSLLLLAIYEQNIKI 691 >gi|115430255 solute carrier family 39 (zinc transporter), member 4 isoform 2 [Homo sapiens] Length = 647 Score = 275 bits (703), Expect = 1e-73 Identities = 200/664 (30%), Positives = 311/664 (46%), Gaps = 89/664 (13%) Query: 39 SSGQPADLLQVLSAGDHPPHNHSRS-LIKTLLEKTGCPRRRNGMQGDCNLCF-------- 89 ++ PA LL +L++G + L+ TL ++ C G C C Sbjct: 21 TASPPAGLLSLLTSGQGALDQEALGGLLNTLADRVHCAN------GPCGKCLSVEDALGL 74 Query: 90 -EPDALLLIAGGNFEDQLREEVVQRVSLLLLYYIIHQEEICSSKLNMSNKEYKFYLHSLL 148 EP+ L G L V R+S + Y+ + E C + +L +LL Sbjct: 75 GEPEGSGLPPG----PVLEARYVARLSAAAVLYLSNPEGTCEDARAGLWASHADHLLALL 130 Query: 149 SLRQ--DEDSSFLSQNETEDILAFTRQYFDTSQSQCMETKTLQKKSGIVSSEGANESTLP 206 + S+L Q R T ++ C++ L +++ + G+ L Sbjct: 131 ESPKALTPGLSWLLQRMQ------ARAAGQTPKTACVDIPQLLEEAVGAGAPGSAGGVL- 183 Query: 207 QLAAMIITLSLQGVCLGQGNLPSPDYFTEYIFSSLNRTNTLRLSELDQLLNTLWTRSTCI 266 A ++ G C LPSP YF +++F + + L+EL L+ L Sbjct: 184 ---AALLDHVRSGSCFHA--LPSPQYFVDFVFQQHSSEVPMTLAELSALMQRLGV----- 233 Query: 267 KNEKIHQFQRKQNNIITHDQDYSNFSSSMEKESEDGPVSWDQTCFSARQLVEIFLQKGLS 326 + H ++ + SSS WD C SAR ++ + + Sbjct: 234 -GREAHSDHSHRHRGASSRDPVPLISSSNSSSV------WDTVCLSARDVMAAYGLSEQA 286 Query: 327 LISKEDFKQMSPGIIQQLLSCSCHLPKDQQAKLPPTTLEKYGYSTVAVTLLTLGSMLGTA 386 ++ E + Q+SP ++QQ LS +C + + E+Y Y ++A L+ L ++ G Sbjct: 287 GVTPEAWAQLSPALLQQQLSGACTSQSRPPVQDQLSQSERYLYGSLATLLICLCAVFGLL 346 Query: 387 LVLFHSCEENYRLILQLFVGLAVGTLSGDALLHLIPQVLGLHKQEAPEFGHFHESKGHIW 446 L+ C ILQ F+ LAVG L+GDA+LHL P+VLGLH S W Sbjct: 347 LLTCTGCRGVTHYILQTFLSLAVGALTGDAVLHLTPKVLGLHTHSEEGL-----SPQPTW 401 Query: 447 KLMGLIGGIHGFFLIEKCFILLV------------------------------SPNDKKS 476 +L+ ++ G++ FFL E F LL+ +P++ + Sbjct: 402 RLLAMLAGLYAFFLFENLFNLLLPRDPEDLEDGPCGHSSHSHGGHSHGVSLQLAPSELRQ 461 Query: 477 PE--------DSQAAEMPIGSMTASNRKCKAISLLAIMILVGDSLHNFADGLAIGAAFSS 528 P+ D A E P R + LL MI +GD++HNFADGLA+GAAF+S Sbjct: 462 PKPPHEGSRADLVAEESPELLNPEPRRLSPELRLLPYMITLGDAVHNFADGLAVGAAFAS 521 Query: 529 SSESGVTTTIAILCHEIPHEMGDFAVLLSSGLSMKTAILMNFISSLTAFMGLYIGLSVSA 588 S ++G+ T++A+ CHE+PHE+GDFA LL +GLS++ A+L+N S+LTAF GLY+ L+V Sbjct: 522 SWKTGLATSLAVFCHELPHELGDFAALLHAGLSVRQALLLNLASALTAFAGLYVALAVGV 581 Query: 589 DPCVQDWIFTVTAGMFLYLSLVEMLPEMTHVQTQRPWMMFLLQNFGLILGWLSLLLLAIY 648 + WI V G+FLY++L +MLP M V+ RPW++FLL N GL+ GW LLLL++Y Sbjct: 582 SEESEAWILAVATGLFLYVALCDMLPAMLKVRDPRPWLLFLLHNVGLLGGWTVLLLLSLY 641 Query: 649 EQNI 652 E +I Sbjct: 642 EDDI 645 >gi|115430259 solute carrier family 39 (zinc transporter), member 4 isoform 1 [Homo sapiens] Length = 622 Score = 271 bits (692), Expect = 2e-72 Identities = 161/464 (34%), Positives = 242/464 (52%), Gaps = 55/464 (11%) Query: 227 LPSPDYFTEYIFSSLNRTNTLRLSELDQLLNTLWTRSTCIKNEKIHQFQRKQNNIITHDQ 286 LPSP YF +++F + + L+EL L+ L + H ++ + Sbjct: 174 LPSPQYFVDFVFQQHSSEVPMTLAELSALMQRLGV------GREAHSDHSHRHRGASSRD 227 Query: 287 DYSNFSSSMEKESEDGPVSWDQTCFSARQLVEIFLQKGLSLISKEDFKQMSPGIIQQLLS 346 SSS WD C SAR ++ + + ++ E + Q+SP ++QQ LS Sbjct: 228 PVPLISSSNSSSV------WDTVCLSARDVMAAYGLSEQAGVTPEAWAQLSPALLQQQLS 281 Query: 347 CSCHLPKDQQAKLPPTTLEKYGYSTVAVTLLTLGSMLGTALVLFHSCEENYRLILQLFVG 406 +C + + E+Y Y ++A L+ L ++ G L+ C ILQ F+ Sbjct: 282 GACTSQSRPPVQDQLSQSERYLYGSLATLLICLCAVFGLLLLTCTGCRGVTHYILQTFLS 341 Query: 407 LAVGTLSGDALLHLIPQVLGLHKQEAPEFGHFHESKGHIWKLMGLIGGIHGFFLIEKCFI 466 LAVG L+GDA+LHL P+VLGLH S W+L+ ++ G++ FFL E F Sbjct: 342 LAVGALTGDAVLHLTPKVLGLHTHSEEGL-----SPQPTWRLLAMLAGLYAFFLFENLFN 396 Query: 467 LLV------------------------------SPNDKKSPE--------DSQAAEMPIG 488 LL+ +P++ + P+ D A E P Sbjct: 397 LLLPRDPEDLEDGPCGHSSHSHGGHSHGVSLQLAPSELRQPKPPHEGSRADLVAEESPEL 456 Query: 489 SMTASNRKCKAISLLAIMILVGDSLHNFADGLAIGAAFSSSSESGVTTTIAILCHEIPHE 548 R + LL MI +GD++HNFADGLA+GAAF+SS ++G+ T++A+ CHE+PHE Sbjct: 457 LNPEPRRLSPELRLLPYMITLGDAVHNFADGLAVGAAFASSWKTGLATSLAVFCHELPHE 516 Query: 549 MGDFAVLLSSGLSMKTAILMNFISSLTAFMGLYIGLSVSADPCVQDWIFTVTAGMFLYLS 608 +GDFA LL +GLS++ A+L+N S+LTAF GLY+ L+V + WI V G+FLY++ Sbjct: 517 LGDFAALLHAGLSVRQALLLNLASALTAFAGLYVALAVGVSEESEAWILAVATGLFLYVA 576 Query: 609 LVEMLPEMTHVQTQRPWMMFLLQNFGLILGWLSLLLLAIYEQNI 652 L +MLP M V+ RPW++FLL N GL+ GW LLLL++YE +I Sbjct: 577 LCDMLPAMLKVRDPRPWLLFLLHNVGLLGGWTVLLLLSLYEDDI 620 >gi|205830424 solute carrier family 39 (zinc transporter), member 14 isoform a [Homo sapiens] Length = 492 Score = 186 bits (471), Expect = 8e-47 Identities = 136/445 (30%), Positives = 216/445 (48%), Gaps = 96/445 (21%) Query: 278 QNNIITHDQDYSNFSSSMEKESEDGPVSWDQTCFSARQLVEIFLQKGLSLISKEDFKQMS 337 + N+ H Q + N S TCFS+ L S I + ++ Sbjct: 75 RGNVTQHVQGHRNLS----------------TCFSSGDLFTAHNFSEQSRIGSSELQEFC 118 Query: 338 PGIIQQLLSCSC------HLPKDQQAKLPPTTLEKYGYSTVAVTLLTLGSMLGTALVLFH 391 P I+QQL S +C + +Q + P+ +E +GY + VT+++L S+LG ++V F Sbjct: 119 PTILQQLDSRACTSENQENEENEQTEEGRPSAVEVWGYGLLCVTVISLCSLLGASVVPFM 178 Query: 392 SCEENYRLILQLFVGLAVGTLSGDALLHLIPQVLGLHKQEAPEFGHFHESKGHIWKLMGL 451 + Y+ +L F+ LA+GTL +AL LIP+ G + E ++ SK + + Sbjct: 179 K-KTFYKRLLLYFIALAIGTLYSNALFQLIPEAFGFNPLE-----DYYVSKSAV-----V 227 Query: 452 IGGIHGFFLIEKCF-ILLVSPND---------------KKSPEDSQAAEMP--------- 486 GG + FF EK ILL N+ KK E+ ++ Sbjct: 228 FGGFYLFFFTEKILKILLKQKNEHHHGHSHYASESLPSKKDQEEGVMEKLQNGDLDHMIP 287 Query: 487 -------------------IGSMT-----ASNRKC--------KAISLLAIMILVGDSLH 514 +GS++ AS C I LA MI + D LH Sbjct: 288 QHCSSELDGKAPMVDEKVIVGSLSVQDLQASQSACYWLKGVRYSDIGTLAWMITLSDGLH 347 Query: 515 NFADGLAIGAAFSSSSESGVTTTIAILCHEIPHEMGDFAVLLSSGLSMKTAILMNFISSL 574 NF DGLAIGA+F+ S G++T++AILC E PHE+GDF +LL++G+S++ A+ NF+S+ Sbjct: 348 NFIDGLAIGASFTVSVFQGISTSVAILCEEFPHELGDFVILLNAGMSIQQALFFNFLSAC 407 Query: 575 TAFMGLYIGLSVSADPCVQDWIFTVTAGMFLYLSLVEMLPEMTHV--QTQRPWMM---FL 629 ++GL G+ ++ +WIF + GMFLY+SL +M PEM V + +R + F+ Sbjct: 408 CCYLGLAFGI-LAGSHFSANWIFALAGGMFLYISLADMFPEMNEVCQEDERKGSILIPFI 466 Query: 630 LQNFGLILGWLSLLLLAIYEQNIKI 654 +QN GL+ G+ +++L +Y I+I Sbjct: 467 IQNLGLLTGFTIMVVLTMYSGQIQI 491 >gi|190360568 solute carrier family 39 (zinc transporter), member 14 isoform a [Homo sapiens] Length = 492 Score = 186 bits (471), Expect = 8e-47 Identities = 136/445 (30%), Positives = 216/445 (48%), Gaps = 96/445 (21%) Query: 278 QNNIITHDQDYSNFSSSMEKESEDGPVSWDQTCFSARQLVEIFLQKGLSLISKEDFKQMS 337 + N+ H Q + N S TCFS+ L S I + ++ Sbjct: 75 RGNVTQHVQGHRNLS----------------TCFSSGDLFTAHNFSEQSRIGSSELQEFC 118 Query: 338 PGIIQQLLSCSC------HLPKDQQAKLPPTTLEKYGYSTVAVTLLTLGSMLGTALVLFH 391 P I+QQL S +C + +Q + P+ +E +GY + VT+++L S+LG ++V F Sbjct: 119 PTILQQLDSRACTSENQENEENEQTEEGRPSAVEVWGYGLLCVTVISLCSLLGASVVPFM 178 Query: 392 SCEENYRLILQLFVGLAVGTLSGDALLHLIPQVLGLHKQEAPEFGHFHESKGHIWKLMGL 451 + Y+ +L F+ LA+GTL +AL LIP+ G + E ++ SK + + Sbjct: 179 K-KTFYKRLLLYFIALAIGTLYSNALFQLIPEAFGFNPLE-----DYYVSKSAV-----V 227 Query: 452 IGGIHGFFLIEKCF-ILLVSPND---------------KKSPEDSQAAEMP--------- 486 GG + FF EK ILL N+ KK E+ ++ Sbjct: 228 FGGFYLFFFTEKILKILLKQKNEHHHGHSHYASESLPSKKDQEEGVMEKLQNGDLDHMIP 287 Query: 487 -------------------IGSMT-----ASNRKC--------KAISLLAIMILVGDSLH 514 +GS++ AS C I LA MI + D LH Sbjct: 288 QHCSSELDGKAPMVDEKVIVGSLSVQDLQASQSACYWLKGVRYSDIGTLAWMITLSDGLH 347 Query: 515 NFADGLAIGAAFSSSSESGVTTTIAILCHEIPHEMGDFAVLLSSGLSMKTAILMNFISSL 574 NF DGLAIGA+F+ S G++T++AILC E PHE+GDF +LL++G+S++ A+ NF+S+ Sbjct: 348 NFIDGLAIGASFTVSVFQGISTSVAILCEEFPHELGDFVILLNAGMSIQQALFFNFLSAC 407 Query: 575 TAFMGLYIGLSVSADPCVQDWIFTVTAGMFLYLSLVEMLPEMTHV--QTQRPWMM---FL 629 ++GL G+ ++ +WIF + GMFLY+SL +M PEM V + +R + F+ Sbjct: 408 CCYLGLAFGI-LAGSHFSANWIFALAGGMFLYISLADMFPEMNEVCQEDERKGSILIPFI 466 Query: 630 LQNFGLILGWLSLLLLAIYEQNIKI 654 +QN GL+ G+ +++L +Y I+I Sbjct: 467 IQNLGLLTGFTIMVVLTMYSGQIQI 491 >gi|190358541 solute carrier family 39 (zinc transporter), member 14 isoform b [Homo sapiens] Length = 492 Score = 180 bits (457), Expect = 3e-45 Identities = 135/447 (30%), Positives = 214/447 (47%), Gaps = 100/447 (22%) Query: 278 QNNIITHDQDYSNFSSSMEKESEDGPVSWDQTCFSARQLVEIFLQKGLSLISKEDFKQMS 337 + N+ H Q + N S TCFS+ L S I + ++ Sbjct: 75 RGNVTQHVQGHRNLS----------------TCFSSGDLFTAHNFSEQSRIGSSELQEFC 118 Query: 338 PGIIQQLLSCSC------HLPKDQQAKLPPTTLEKYGYSTVAVTLLTLGSMLGTALVLFH 391 P I+QQL S +C + +Q + P+ +E +G+ ++V+L+ L S+LG VL Sbjct: 119 PTILQQLDSRACTSENQENEENEQTEEGRPSAVEVWGFGFLSVSLINLASLLG---VLVL 175 Query: 392 SCEEN--YRLILQLFVGLAVGTLSGDALLHLIPQVLGLHKQEAPEFGHFHESKGHIWKLM 449 C E + +L F+ L++GTL +AL LIP+ G + E ++ SK + Sbjct: 176 PCTEKAFFSRVLTYFIALSIGTLLSNALFQLIPEAFGFNPLE-----DYYVSKSAV---- 226 Query: 450 GLIGGIHGFFLIEKCF-ILLVSPND---------------KKSPEDSQAAEMP------- 486 + GG + FF EK ILL N+ KK E+ ++ Sbjct: 227 -VFGGFYLFFFTEKILKILLKQKNEHHHGHSHYASESLPSKKDQEEGVMEKLQNGDLDHM 285 Query: 487 ---------------------IGSMT-----ASNRKC--------KAISLLAIMILVGDS 512 +GS++ AS C I LA MI + D Sbjct: 286 IPQHCSSELDGKAPMVDEKVIVGSLSVQDLQASQSACYWLKGVRYSDIGTLAWMITLSDG 345 Query: 513 LHNFADGLAIGAAFSSSSESGVTTTIAILCHEIPHEMGDFAVLLSSGLSMKTAILMNFIS 572 LHNF DGLAIGA+F+ S G++T++AILC E PHE+GDF +LL++G+S++ A+ NF+S Sbjct: 346 LHNFIDGLAIGASFTVSVFQGISTSVAILCEEFPHELGDFVILLNAGMSIQQALFFNFLS 405 Query: 573 SLTAFMGLYIGLSVSADPCVQDWIFTVTAGMFLYLSLVEMLPEMTHV--QTQRPWMM--- 627 + ++GL G+ ++ +WIF + GMFLY+SL +M PEM V + +R + Sbjct: 406 ACCCYLGLAFGI-LAGSHFSANWIFALAGGMFLYISLADMFPEMNEVCQEDERKGSILIP 464 Query: 628 FLLQNFGLILGWLSLLLLAIYEQNIKI 654 F++QN GL+ G+ +++L +Y I+I Sbjct: 465 FIIQNLGLLTGFTIMVVLTMYSGQIQI 491 >gi|24586665 solute carrier family 39 (zinc transporter), member 8 isoform a [Homo sapiens] Length = 460 Score = 173 bits (439), Expect = 4e-43 Identities = 121/412 (29%), Positives = 201/412 (48%), Gaps = 74/412 (17%) Query: 300 EDGPVSWDQTCFSARQLVEIFLQKGLSLISKEDFKQMSPGIIQQLLSCSCH-LPKDQQAK 358 E G + ++Q C +A ++ + + I+ F + P ++QQL C PK K Sbjct: 65 EPGQLHFNQ-CLTAEEIFSLHGFSNATQITSSKFSVICPAVLQQLNFHPCEDRPKH---K 120 Query: 359 LPPTTLEKYGYSTVAVTLLTLGSMLGTALVLFHSCEENY-RLILQLFVGLAVGTLSGDAL 417 P+ E +GY ++VT++ L S+LG L+L +++Y IL FVGLA+GTL +A+ Sbjct: 121 TRPSHSEVWGYGFLSVTIINLASLLG--LILTPLIKKSYFPKILTFFVGLAIGTLFSNAI 178 Query: 418 LHLIPQVLGLHKQEAPEFGHFHESKGHIWKLMGLIGGIHGFFLIEKCFILLVSP------ 471 LIP+ FG + ++ K + + GG + F E+ +L+ Sbjct: 179 FQLIPEA----------FGFDPKVDSYVEKAVAVFGGFYLLFFFERMLKMLLKTYGQNGH 228 Query: 472 ----NDKKSPEDS---------------------------------------QAAEMPIG 488 ND P++ + P Sbjct: 229 THFGNDNFGPQEKTHQPKALPAINGVTCYANPAVTEANGHIHFDNVSVVSLQDGKKEPSS 288 Query: 489 SMTASNRKCKAISLLAIMILVGDSLHNFADGLAIGAAFSSSSESGVTTTIAILCHEIPHE 548 K I +A MI + D+LHNF DGLAIGA+ + S G++T+IAILC E PHE Sbjct: 289 CTCLKGPKLSEIGTIAWMITLCDALHNFIDGLAIGASCTLSLLQGLSTSIAILCEEFPHE 348 Query: 549 MGDFAVLLSSGLSMKTAILMNFISSLTAFMGLYIGLSVSADPCVQDWIFTVTAGMFLYLS 608 +GDF +LL++G+S + A+L NF+S+ + ++GL G+ V + + IF + GMFLY+S Sbjct: 349 LGDFVILLNAGMSTRQALLFNFLSACSCYVGLAFGILV-GNNFAPNIIFALAGGMFLYIS 407 Query: 609 LVEMLPEMTHVQTQR------PWMMFLLQNFGLILGWLSLLLLAIYEQNIKI 654 L +M PEM + ++ + F++QN G++ G+ ++LL+ +Y I++ Sbjct: 408 LADMFPEMNDMLREKVTGRKTDFTFFMIQNAGMLTGFTAILLITLYAGEIEL 459 >gi|205830403 solute carrier family 39 (zinc transporter), member 8 isoform a [Homo sapiens] Length = 460 Score = 173 bits (439), Expect = 4e-43 Identities = 121/412 (29%), Positives = 201/412 (48%), Gaps = 74/412 (17%) Query: 300 EDGPVSWDQTCFSARQLVEIFLQKGLSLISKEDFKQMSPGIIQQLLSCSCH-LPKDQQAK 358 E G + ++Q C +A ++ + + I+ F + P ++QQL C PK K Sbjct: 65 EPGQLHFNQ-CLTAEEIFSLHGFSNATQITSSKFSVICPAVLQQLNFHPCEDRPKH---K 120 Query: 359 LPPTTLEKYGYSTVAVTLLTLGSMLGTALVLFHSCEENY-RLILQLFVGLAVGTLSGDAL 417 P+ E +GY ++VT++ L S+LG L+L +++Y IL FVGLA+GTL +A+ Sbjct: 121 TRPSHSEVWGYGFLSVTIINLASLLG--LILTPLIKKSYFPKILTFFVGLAIGTLFSNAI 178 Query: 418 LHLIPQVLGLHKQEAPEFGHFHESKGHIWKLMGLIGGIHGFFLIEKCFILLVSP------ 471 LIP+ FG + ++ K + + GG + F E+ +L+ Sbjct: 179 FQLIPEA----------FGFDPKVDSYVEKAVAVFGGFYLLFFFERMLKMLLKTYGQNGH 228 Query: 472 ----NDKKSPEDS---------------------------------------QAAEMPIG 488 ND P++ + P Sbjct: 229 THFGNDNFGPQEKTHQPKALPAINGVTCYANPAVTEANGHIHFDNVSVVSLQDGKKEPSS 288 Query: 489 SMTASNRKCKAISLLAIMILVGDSLHNFADGLAIGAAFSSSSESGVTTTIAILCHEIPHE 548 K I +A MI + D+LHNF DGLAIGA+ + S G++T+IAILC E PHE Sbjct: 289 CTCLKGPKLSEIGTIAWMITLCDALHNFIDGLAIGASCTLSLLQGLSTSIAILCEEFPHE 348 Query: 549 MGDFAVLLSSGLSMKTAILMNFISSLTAFMGLYIGLSVSADPCVQDWIFTVTAGMFLYLS 608 +GDF +LL++G+S + A+L NF+S+ + ++GL G+ V + + IF + GMFLY+S Sbjct: 349 LGDFVILLNAGMSTRQALLFNFLSACSCYVGLAFGILV-GNNFAPNIIFALAGGMFLYIS 407 Query: 609 LVEMLPEMTHVQTQR------PWMMFLLQNFGLILGWLSLLLLAIYEQNIKI 654 L +M PEM + ++ + F++QN G++ G+ ++LL+ +Y I++ Sbjct: 408 LADMFPEMNDMLREKVTGRKTDFTFFMIQNAGMLTGFTAILLITLYAGEIEL 459 >gi|205830407 solute carrier family 39 (zinc transporter), member 8 isoform c [Homo sapiens] Length = 393 Score = 172 bits (435), Expect = 1e-42 Identities = 118/402 (29%), Positives = 195/402 (48%), Gaps = 73/402 (18%) Query: 310 CFSARQLVEIFLQKGLSLISKEDFKQMSPGIIQQLLSCSCH-LPKDQQAKLPPTTLEKYG 368 C +A ++ + + I+ F + P ++QQL C PK K P+ E +G Sbjct: 7 CLTAEEIFSLHGFSNATQITSSKFSVICPAVLQQLNFHPCEDRPKH---KTRPSHSEVWG 63 Query: 369 YSTVAVTLLTLGSMLGTALVLFHSCEENY-RLILQLFVGLAVGTLSGDALLHLIPQVLGL 427 Y ++VT++ L S+LG L+L +++Y IL FVGLA+GTL +A+ LIP+ Sbjct: 64 YGFLSVTIINLASLLG--LILTPLIKKSYFPKILTFFVGLAIGTLFSNAIFQLIPEA--- 118 Query: 428 HKQEAPEFGHFHESKGHIWKLMGLIGGIHGFFLIEKCFILLVSP----------NDKKSP 477 FG + ++ K + + GG + F E+ +L+ ND P Sbjct: 119 -------FGFDPKVDSYVEKAVAVFGGFYLLFFFERMLKMLLKTYGQNGHTHFGNDNFGP 171 Query: 478 EDS---------------------------------------QAAEMPIGSMTASNRKCK 498 ++ + P K Sbjct: 172 QEKTHQPKALPAINGVTCYANPAVTEANGHIHFDNVSVVSLQDGKKEPSSCTCLKGPKLS 231 Query: 499 AISLLAIMILVGDSLHNFADGLAIGAAFSSSSESGVTTTIAILCHEIPHEMGDFAVLLSS 558 I +A MI + D+LHNF DGLAIGA+ + S G++T+IAILC E PHE+GDF +LL++ Sbjct: 232 EIGTIAWMITLCDALHNFIDGLAIGASCTLSLLQGLSTSIAILCEEFPHELGDFVILLNA 291 Query: 559 GLSMKTAILMNFISSLTAFMGLYIGLSVSADPCVQDWIFTVTAGMFLYLSLVEMLPEMTH 618 G+S + A+L NF+S+ + ++GL G+ V + + IF + GMFLY+SL +M PEM Sbjct: 292 GMSTRQALLFNFLSACSCYVGLAFGILV-GNNFAPNIIFALAGGMFLYISLADMFPEMND 350 Query: 619 VQTQR------PWMMFLLQNFGLILGWLSLLLLAIYEQNIKI 654 + ++ + F++QN G++ G+ ++LL+ +Y I++ Sbjct: 351 MLREKVTGRKTDFTFFMIQNAGMLTGFTAILLITLYAGEIEL 392 >gi|205830426 solute carrier family 39 (zinc transporter), member 14 isoform c [Homo sapiens] Length = 481 Score = 166 bits (420), Expect = 6e-41 Identities = 131/432 (30%), Positives = 202/432 (46%), Gaps = 92/432 (21%) Query: 278 QNNIITHDQDYSNFSSSMEKESEDGPVSWDQTCFSARQLVEIFLQKGLSLISKEDFKQMS 337 + N+ H Q + N S TCFS+ L S I + ++ Sbjct: 75 RGNVTQHVQGHRNLS----------------TCFSSGDLFTAHNFSEQSRIGSSELQEFC 118 Query: 338 PGIIQQLLSCSC------HLPKDQQAKLPPTTLEKYGYSTVAVTLLTLGSMLGTALVLFH 391 P I+QQL S +C + +Q + P+ +E +GY + VT+++L S+LG ++V F Sbjct: 119 PTILQQLDSRACTSENQENEENEQTEEGRPSAVEVWGYGLLCVTVISLCSLLGASVVPFM 178 Query: 392 SCEENYRLILQLFVGLAVGTLSGDALLHLIPQVLGLHKQEAPEFGHFHESKGHIWKLMGL 451 + Y+ +L F+ LA+GTL +AL LIP+ G + E ++ SK + + Sbjct: 179 K-KTFYKRLLLYFIALAIGTLYSNALFQLIPEAFGFNPLE-----DYYVSKSAV-----V 227 Query: 452 IGGIHGFFLIEKCF-ILLVSPND---------------KKSPEDSQAAEMP--------- 486 GG + FF EK ILL N+ KK E+ ++ Sbjct: 228 FGGFYLFFFTEKILKILLKQKNEHHHGHSHYASESLPSKKDQEEGVMEKLQNGDLDHMIP 287 Query: 487 -------------------IGSMT-----ASNRKC--------KAISLLAIMILVGDSLH 514 +GS++ AS C I LA MI + D LH Sbjct: 288 QHCSSELDGKAPMVDEKVIVGSLSVQDLQASQSACYWLKGVRYSDIGTLAWMITLSDGLH 347 Query: 515 NFADGLAIGAAFSSSSESGVTTTIAILCHEIPHEMGDFAVLLSSGLSMKTAILMNFISSL 574 NF DGLAIGA+F+ S G++T++AILC E PHE+GDF +LL++G+S++ A+ NF+S+ Sbjct: 348 NFIDGLAIGASFTVSVFQGISTSVAILCEEFPHELGDFVILLNAGMSIQQALFFNFLSAC 407 Query: 575 TAFMGLYIGLSVSADPCVQDWIFTVTAGMFLYLSLVEMLPEMTHVQTQRPWM-MFLLQNF 633 ++GL G+ ++ +WIF + GMFLY+SL +M+ + Q W + LQ Sbjct: 408 CCYLGLAFGI-LAGSHFSANWIFALAGGMFLYISLADMMEFCSVAQAGVQWCHLSSLQPL 466 Query: 634 GLILGWLSLLLL 645 L L LS L L Sbjct: 467 PLGLKRLSCLSL 478 >gi|206597541 solute carrier family 39 (metal ion transporter), member 5 [Homo sapiens] Length = 540 Score = 162 bits (411), Expect = 7e-40 Identities = 126/389 (32%), Positives = 186/389 (47%), Gaps = 53/389 (13%) Query: 307 DQTCFSARQLVEIFLQKGLSLISKEDFKQMSPGIIQQLLSCSCHLPKDQQAKLPP-TTLE 365 ++ C + QL+ F + ++ F + P ++ Q+ S C A PP L Sbjct: 155 NEDCLNGSQLLVNFGLSPAAPLTPRQFALLCPALLYQIDSRVCI---GAPAPAPPGDLLS 211 Query: 366 KYGYSTVAVTLLTLGSMLGTALVLFHSCEENYRLILQLFVGLAVGTLSGDALLHLIPQVL 425 S +AV LL+L S L L+ R +L LAVGTL GDALLHL+P Sbjct: 212 ALLQSALAVLLLSLPSPLSLLLLRLLG-PRLLRPLLGFLGALAVGTLCGDALLHLLP--- 267 Query: 426 GLHKQEAPEFGHFHESKGHIWKLMGLIGGIHGFFLIEKCFILL----VSPNDKK------ 475 H QE G + + + ++GG+ F++E LL + P + Sbjct: 268 --HAQEGRHAGPGGLPEKDLGPGLSVLGGLFLLFVLENMLGLLRHRGLRPRCCRRKRRNL 325 Query: 476 -----SPEDS--------QAAEMPIGSMTASNRKCKAISLLAI----------------- 505 PE+ QAA P G+ + + LA Sbjct: 326 ETRNLDPENGSGMALQPLQAAPEP-GAQGQREKNSQHPPALAPPGHQGHSHGHQGGTDIT 384 Query: 506 -MILVGDSLHNFADGLAIGAAFSSSSESGVTTTIAILCHEIPHEMGDFAVLLSSGLSMKT 564 M+L+GD LHN DGLAIGAAFS SG++TT+A+ CHE+PHE+GDFA+LL SGLS + Sbjct: 385 WMVLLGDGLHNLTDGLAIGAAFSDGFSSGLSTTLAVFCHELPHELGDFAMLLQSGLSFRR 444 Query: 565 AILMNFISSLTAFMGLYIGLSVSADPC-VQDWIFTVTAGMFLYLSLVEMLPEMTHVQTQR 623 +L++ +S G +G+ +S P + W+F VTAG+FLY++LV+MLP + Sbjct: 445 LLLLSLVSGALGLGGAVLGVGLSLGPVPLTPWVFGVTAGVFLYVALVDMLPALLRPPEPL 504 Query: 624 PWMMFLLQNFGLILGWLSLLLLAIYEQNI 652 P LLQ GL+LG +L + + E+ + Sbjct: 505 PTPHVLLQGLGLLLGGGLMLAITLLEERL 533 >gi|206597539 solute carrier family 39 (metal ion transporter), member 5 [Homo sapiens] Length = 540 Score = 162 bits (411), Expect = 7e-40 Identities = 126/389 (32%), Positives = 186/389 (47%), Gaps = 53/389 (13%) Query: 307 DQTCFSARQLVEIFLQKGLSLISKEDFKQMSPGIIQQLLSCSCHLPKDQQAKLPP-TTLE 365 ++ C + QL+ F + ++ F + P ++ Q+ S C A PP L Sbjct: 155 NEDCLNGSQLLVNFGLSPAAPLTPRQFALLCPALLYQIDSRVCI---GAPAPAPPGDLLS 211 Query: 366 KYGYSTVAVTLLTLGSMLGTALVLFHSCEENYRLILQLFVGLAVGTLSGDALLHLIPQVL 425 S +AV LL+L S L L+ R +L LAVGTL GDALLHL+P Sbjct: 212 ALLQSALAVLLLSLPSPLSLLLLRLLG-PRLLRPLLGFLGALAVGTLCGDALLHLLP--- 267 Query: 426 GLHKQEAPEFGHFHESKGHIWKLMGLIGGIHGFFLIEKCFILL----VSPNDKK------ 475 H QE G + + + ++GG+ F++E LL + P + Sbjct: 268 --HAQEGRHAGPGGLPEKDLGPGLSVLGGLFLLFVLENMLGLLRHRGLRPRCCRRKRRNL 325 Query: 476 -----SPEDS--------QAAEMPIGSMTASNRKCKAISLLAI----------------- 505 PE+ QAA P G+ + + LA Sbjct: 326 ETRNLDPENGSGMALQPLQAAPEP-GAQGQREKNSQHPPALAPPGHQGHSHGHQGGTDIT 384 Query: 506 -MILVGDSLHNFADGLAIGAAFSSSSESGVTTTIAILCHEIPHEMGDFAVLLSSGLSMKT 564 M+L+GD LHN DGLAIGAAFS SG++TT+A+ CHE+PHE+GDFA+LL SGLS + Sbjct: 385 WMVLLGDGLHNLTDGLAIGAAFSDGFSSGLSTTLAVFCHELPHELGDFAMLLQSGLSFRR 444 Query: 565 AILMNFISSLTAFMGLYIGLSVSADPC-VQDWIFTVTAGMFLYLSLVEMLPEMTHVQTQR 623 +L++ +S G +G+ +S P + W+F VTAG+FLY++LV+MLP + Sbjct: 445 LLLLSLVSGALGLGGAVLGVGLSLGPVPLTPWVFGVTAGVFLYVALVDMLPALLRPPEPL 504 Query: 624 PWMMFLLQNFGLILGWLSLLLLAIYEQNI 652 P LLQ GL+LG +L + + E+ + Sbjct: 505 PTPHVLLQGLGLLLGGGLMLAITLLEERL 533 >gi|187936949 solute carrier family 39 (zinc transporter), member 10 [Homo sapiens] Length = 831 Score = 161 bits (408), Expect = 2e-39 Identities = 80/169 (47%), Positives = 119/169 (70%), Gaps = 7/169 (4%) Query: 491 TASNRKCKAISLLAIMILVGDSLHNFADGLAIGAAFSSSSESGVTTTIAILCHEIPHEMG 550 + S+ K I+ +A M+++GD +HNF+DGLAIGAAFS+ G++T+IA+ CHE+PHE+G Sbjct: 657 SGSDLKETGIANIAWMVIMGDGIHNFSDGLAIGAAFSAGLTGGISTSIAVFCHELPHELG 716 Query: 551 DFAVLLSSGLSMKTAILMNFISSLTAFMGLYIGLSVSA-DPCVQDWIFTVTAGMFLYLSL 609 DFAVLL +G+++K AI+ N +S++ A++G+ IG +V + WIF VTAGMFLY++L Sbjct: 717 DFAVLLKAGMTVKQAIVYNLLSAMMAYIGMLIGTAVGQYANNITLWIFAVTAGMFLYVAL 776 Query: 610 VEMLPEMTHVQTQR------PWMMFLLQNFGLILGWLSLLLLAIYEQNI 652 V+MLPEM H P F+LQN GL+ G+ +L++A+YE I Sbjct: 777 VDMLPEMLHGDGDNEEHGFCPVGQFILQNLGLLFGFAIMLVIALYEDKI 825 Score = 68.9 bits (167), Expect = 1e-11 Identities = 57/181 (31%), Positives = 86/181 (47%), Gaps = 29/181 (16%) Query: 310 CFSARQLVEIFLQKGLSLISKEDFKQMSPGIIQQLLSCSC--HLPK------DQQAKLPP 361 C + QL++ + S IS + F + P ++ Q+ S C H K ++ L P Sbjct: 337 CLNVTQLLKYYGHGANSPISTDLFTYLCPALLYQIDSRLCIEHFDKLLVEDINKDKNLVP 396 Query: 362 TTLEKYGYST-----VAVTLLTLGSMLGTALV--LFHSCEENYRLILQLFVGLAVGTLSG 414 G S +++T+++L S+LG LV + C ++ +L V LAVGT+SG Sbjct: 397 EDEANIGASAWICGIISITVISLLSLLGVILVPIINQGC---FKFLLTFLVALAVGTMSG 453 Query: 415 DALLHLIPQVLGLH---KQEAPEFGHFH--------ESKGHIWKLMGLIGGIHGFFLIEK 463 DALLHL+P G H Q A GH H E + K + +GGI+ F+IE Sbjct: 454 DALLHLLPHSQGGHDHSHQHAHGHGHSHGHESNKFLEEYDAVLKGLVALGGIYLLFIIEH 513 Query: 464 C 464 C Sbjct: 514 C 514 >gi|55741750 solute carrier family 39 (zinc transporter), member 10 [Homo sapiens] Length = 831 Score = 161 bits (408), Expect = 2e-39 Identities = 80/169 (47%), Positives = 119/169 (70%), Gaps = 7/169 (4%) Query: 491 TASNRKCKAISLLAIMILVGDSLHNFADGLAIGAAFSSSSESGVTTTIAILCHEIPHEMG 550 + S+ K I+ +A M+++GD +HNF+DGLAIGAAFS+ G++T+IA+ CHE+PHE+G Sbjct: 657 SGSDLKETGIANIAWMVIMGDGIHNFSDGLAIGAAFSAGLTGGISTSIAVFCHELPHELG 716 Query: 551 DFAVLLSSGLSMKTAILMNFISSLTAFMGLYIGLSVSA-DPCVQDWIFTVTAGMFLYLSL 609 DFAVLL +G+++K AI+ N +S++ A++G+ IG +V + WIF VTAGMFLY++L Sbjct: 717 DFAVLLKAGMTVKQAIVYNLLSAMMAYIGMLIGTAVGQYANNITLWIFAVTAGMFLYVAL 776 Query: 610 VEMLPEMTHVQTQR------PWMMFLLQNFGLILGWLSLLLLAIYEQNI 652 V+MLPEM H P F+LQN GL+ G+ +L++A+YE I Sbjct: 777 VDMLPEMLHGDGDNEEHGFCPVGQFILQNLGLLFGFAIMLVIALYEDKI 825 Score = 68.9 bits (167), Expect = 1e-11 Identities = 57/181 (31%), Positives = 86/181 (47%), Gaps = 29/181 (16%) Query: 310 CFSARQLVEIFLQKGLSLISKEDFKQMSPGIIQQLLSCSC--HLPK------DQQAKLPP 361 C + QL++ + S IS + F + P ++ Q+ S C H K ++ L P Sbjct: 337 CLNVTQLLKYYGHGANSPISTDLFTYLCPALLYQIDSRLCIEHFDKLLVEDINKDKNLVP 396 Query: 362 TTLEKYGYST-----VAVTLLTLGSMLGTALV--LFHSCEENYRLILQLFVGLAVGTLSG 414 G S +++T+++L S+LG LV + C ++ +L V LAVGT+SG Sbjct: 397 EDEANIGASAWICGIISITVISLLSLLGVILVPIINQGC---FKFLLTFLVALAVGTMSG 453 Query: 415 DALLHLIPQVLGLH---KQEAPEFGHFH--------ESKGHIWKLMGLIGGIHGFFLIEK 463 DALLHL+P G H Q A GH H E + K + +GGI+ F+IE Sbjct: 454 DALLHLLPHSQGGHDHSHQHAHGHGHSHGHESNKFLEEYDAVLKGLVALGGIYLLFIIEH 513 Query: 464 C 464 C Sbjct: 514 C 514 >gi|205830405 solute carrier family 39 (zinc transporter), member 8 isoform b [Homo sapiens] Length = 444 Score = 157 bits (397), Expect = 3e-38 Identities = 112/375 (29%), Positives = 180/375 (48%), Gaps = 68/375 (18%) Query: 300 EDGPVSWDQTCFSARQLVEIFLQKGLSLISKEDFKQMSPGIIQQLLSCSCH-LPKDQQAK 358 E G + ++Q C +A ++ + + I+ F + P ++QQL C PK K Sbjct: 65 EPGQLHFNQ-CLTAEEIFSLHGFSNATQITSSKFSVICPAVLQQLNFHPCEDRPKH---K 120 Query: 359 LPPTTLEKYGYSTVAVTLLTLGSMLGTALVLFHSCEENY-RLILQLFVGLAVGTLSGDAL 417 P+ E +GY ++VT++ L S+LG L+L +++Y IL FVGLA+GTL +A+ Sbjct: 121 TRPSHSEVWGYGFLSVTIINLASLLG--LILTPLIKKSYFPKILTFFVGLAIGTLFSNAI 178 Query: 418 LHLIPQVLGLHKQEAPEFGHFHESKGHIWKLMGLIGGIHGFFLIEKCFILLVSP------ 471 LIP+ FG + ++ K + + GG + F E+ +L+ Sbjct: 179 FQLIPEA----------FGFDPKVDSYVEKAVAVFGGFYLLFFFERMLKMLLKTYGQNGH 228 Query: 472 ----NDKKSPEDS---------------------------------------QAAEMPIG 488 ND P++ + P Sbjct: 229 THFGNDNFGPQEKTHQPKALPAINGVTCYANPAVTEANGHIHFDNVSVVSLQDGKKEPSS 288 Query: 489 SMTASNRKCKAISLLAIMILVGDSLHNFADGLAIGAAFSSSSESGVTTTIAILCHEIPHE 548 K I +A MI + D+LHNF DGLAIGA+ + S G++T+IAILC E PHE Sbjct: 289 CTCLKGPKLSEIGTIAWMITLCDALHNFIDGLAIGASCTLSLLQGLSTSIAILCEEFPHE 348 Query: 549 MGDFAVLLSSGLSMKTAILMNFISSLTAFMGLYIGLSVSADPCVQDWIFTVTAGMFLYLS 608 +GDF +LL++G+S + A+L NF+S+ + ++GL G+ V + + IF + GMFLY+S Sbjct: 349 LGDFVILLNAGMSTRQALLFNFLSACSCYVGLAFGILV-GNNFAPNIIFALAGGMFLYIS 407 Query: 609 LVEMLPEMTHVQTQR 623 L +M PEM + ++ Sbjct: 408 LADMFPEMNDMLREK 422 >gi|153252201 solute carrier family 39 (zinc transporter), member 6 isoform 1 [Homo sapiens] Length = 755 Score = 156 bits (394), Expect = 6e-38 Identities = 74/162 (45%), Positives = 115/162 (70%), Gaps = 5/162 (3%) Query: 496 KCKAISLLAIMILVGDSLHNFADGLAIGAAFSSSSESGVTTTIAILCHEIPHEMGDFAVL 555 K ++ LA M+++GD LHNF+DGLAIGAAF+ SG++T++A+ CHE+PHE+GDFAVL Sbjct: 588 KDAGVATLAWMVIMGDGLHNFSDGLAIGAAFTEGLSSGLSTSVAVFCHELPHELGDFAVL 647 Query: 556 LSSGLSMKTAILMNFISSLTAFMGLYIGLSVS-ADPCVQDWIFTVTAGMFLYLSLVEMLP 614 L +G+++K A+L N +S++ A++G+ G+ + V WIF +TAG+F+Y++LV+M+P Sbjct: 648 LKAGMTVKQAVLYNALSAMLAYLGMATGIFIGHYAENVSMWIFALTAGLFMYVALVDMVP 707 Query: 615 EMTHVQTQ----RPWMMFLLQNFGLILGWLSLLLLAIYEQNI 652 EM H W F LQN G++LG+ +LL++I+E I Sbjct: 708 EMLHNDASDHGCSRWGYFFLQNAGMLLGFGIMLLISIFEHKI 749 Score = 71.2 bits (173), Expect = 3e-12 Identities = 57/209 (27%), Positives = 96/209 (45%), Gaps = 35/209 (16%) Query: 308 QTCFSARQLVEIFLQKGLSL---ISKEDFKQMSPGIIQQLLSCSCHL-PKDQQAKLPPTT 363 Q CF+A +L+ G+ + ++ +F + P II Q+ + SC + +++A++PP T Sbjct: 262 QECFNASKLLT---SHGMGIQVPLNATEFNYLCPAIINQIDARSCLIHTSEKKAEIPPKT 318 Query: 364 LE---KYGYSTVAVTLLTLGSMLGTALVLFHSCEENYRLILQLFVGLAVGTLSGDALLHL 420 + +A+++++ S+LG LV + ++ +L V LAVGTLSGDA LHL Sbjct: 319 YSLQIAWVGGFIAISIISFLSLLGVILVPLMN-RVFFKFLLSFLVALAVGTLSGDAFLHL 377 Query: 421 IPQVLGLH------------KQEAPEFGHFHESK-------GHIWKLMGLIGGIHGFFLI 461 +P H + P F H WK + +GG++ FL+ Sbjct: 378 LPHSHASHHHSHSHEEPAMEMKRGPLFSHLSSQNIEESAYFDSTWKGLTALGGLYFMFLV 437 Query: 462 EKCFILLVSPNDK-----KSPEDSQAAEM 485 E L+ DK K PE+ E+ Sbjct: 438 EHVLTLIKQFKDKKKKNQKKPENDDDVEI 466 >gi|153252214 solute carrier family 39 (zinc transporter), member 6 isoform 2 [Homo sapiens] Length = 433 Score = 128 bits (321), Expect = 2e-29 Identities = 57/119 (47%), Positives = 91/119 (76%), Gaps = 1/119 (0%) Query: 496 KCKAISLLAIMILVGDSLHNFADGLAIGAAFSSSSESGVTTTIAILCHEIPHEMGDFAVL 555 K ++ LA M+++GD LHNF+DGLAIGAAF+ SG++T++A+ CHE+PHE+GDFAVL Sbjct: 313 KDAGVATLAWMVIMGDGLHNFSDGLAIGAAFTEGLSSGLSTSVAVFCHELPHELGDFAVL 372 Query: 556 LSSGLSMKTAILMNFISSLTAFMGLYIGLSVS-ADPCVQDWIFTVTAGMFLYLSLVEML 613 L +G+++K A+L N +S++ A++G+ G+ + V WIF +TAG+F+Y++LV+M+ Sbjct: 373 LKAGMTVKQAVLYNALSAMLAYLGMATGIFIGHYAENVSMWIFALTAGLFMYVALVDMV 431 Score = 67.8 bits (164), Expect = 3e-11 Identities = 51/186 (27%), Positives = 85/186 (45%), Gaps = 29/186 (15%) Query: 328 ISKEDFKQMSPGIIQQLLSCSCHL-PKDQQAKLPPTTLE---KYGYSTVAVTLLTLGSML 383 ++ +F + P II Q+ + SC + +++A++PP T + +A+++++ S+L Sbjct: 7 LNATEFNYLCPAIINQIDARSCLIHTSEKKAEIPPKTYSLQIAWVGGFIAISIISFLSLL 66 Query: 384 GTALVLFHSCEENYRLILQLFVGLAVGTLSGDALLHLIPQVLGLH------------KQE 431 G LV + ++ +L V LAVGTLSGDA LHL+P H + Sbjct: 67 GVILVPLMN-RVFFKFLLSFLVALAVGTLSGDAFLHLLPHSHASHHHSHSHEEPAMEMKR 125 Query: 432 APEFGHFHESK-------GHIWKLMGLIGGIHGFFLIEKCFILLVSPNDK-----KSPED 479 P F H WK + +GG++ FL+E L+ DK K PE+ Sbjct: 126 GPLFSHLSSQNIEESAYFDSTWKGLTALGGLYFMFLVEHVLTLIKQFKDKKKKNQKKPEN 185 Query: 480 SQAAEM 485 E+ Sbjct: 186 DDDVEI 191 >gi|117553619 solute carrier family 39, member 7 [Homo sapiens] Length = 469 Score = 127 bits (318), Expect = 4e-29 Identities = 97/339 (28%), Positives = 151/339 (44%), Gaps = 60/339 (17%) Query: 367 YGYSTVAVTLLTLGSMLGTALVLFHSCEENYRLILQLFVGLAVGTLSGDALLHLIPQVLG 426 + Y+ A L++ L+ S +R +LQ+ + A G L GDA LHLIP L Sbjct: 135 WAYALGATVLISAAPFFVLFLIPVESNSPRHRSLLQILLSFASGGLLGDAFLHLIPHALE 194 Query: 427 LHKQ---EAPEFGHFHESKGHIWKL-MGLIGGIHGFFLIEKCFILLV------------- 469 H E P GH H +G I + + ++ GI F ++EK F+ V Sbjct: 195 PHSHHTLEQPGHGHSHSGQGPILSVGLWVLSGIVAFLVVEK-FVRHVKGGHGHSHGHGHA 253 Query: 470 ---------------SPNDKKSPEDSQAA---------------EMPIGSMTASNRKCKA 499 S +K+S E+ + + P+ A K Sbjct: 254 HSHTRGSHGHGRQERSTKEKQSSEEEEKETRGVQKRRGGSTVPKDGPVRPQNAEEEKRGL 313 Query: 500 -ISLLAIMILVGDSLHNFADGLAIGAAFSSSSESGVTTTIAILCHEIPHEMGDFAVLLSS 558 + + + L D HNF DGLAIGA+F G+ TT+ +L HE+PHE+GDFA+L+ S Sbjct: 314 DLRVSGYLNLAADLAHNFTDGLAIGASFRGGRGLGILTTMTVLLHEVPHEVGDFAILVQS 373 Query: 559 GLSMKTAILMNFISSLTAFMGLYIGL--------SVSADPCVQDWIFTVTAGMFLYLSLV 610 G S K A+ + ++++ A G L S A W+ TAG F+Y++ V Sbjct: 374 GCSKKQAMRLQLLTAVGALAGTACALLTEGGAVGSEIAGGAGPGWVLPFTAGGFIYVATV 433 Query: 611 EMLPEMTHVQTQRPWMMFLLQNFGLILGWLSLLLLAIYE 649 +LPE+ + + LL+ GL+ G + ++L+A E Sbjct: 434 SVLPELLREASP---LQSLLEVLGLLGGVIMMVLIAHLE 469 >gi|117553608 solute carrier family 39, member 7 [Homo sapiens] Length = 469 Score = 127 bits (318), Expect = 4e-29 Identities = 97/339 (28%), Positives = 151/339 (44%), Gaps = 60/339 (17%) Query: 367 YGYSTVAVTLLTLGSMLGTALVLFHSCEENYRLILQLFVGLAVGTLSGDALLHLIPQVLG 426 + Y+ A L++ L+ S +R +LQ+ + A G L GDA LHLIP L Sbjct: 135 WAYALGATVLISAAPFFVLFLIPVESNSPRHRSLLQILLSFASGGLLGDAFLHLIPHALE 194 Query: 427 LHKQ---EAPEFGHFHESKGHIWKL-MGLIGGIHGFFLIEKCFILLV------------- 469 H E P GH H +G I + + ++ GI F ++EK F+ V Sbjct: 195 PHSHHTLEQPGHGHSHSGQGPILSVGLWVLSGIVAFLVVEK-FVRHVKGGHGHSHGHGHA 253 Query: 470 ---------------SPNDKKSPEDSQAA---------------EMPIGSMTASNRKCKA 499 S +K+S E+ + + P+ A K Sbjct: 254 HSHTRGSHGHGRQERSTKEKQSSEEEEKETRGVQKRRGGSTVPKDGPVRPQNAEEEKRGL 313 Query: 500 -ISLLAIMILVGDSLHNFADGLAIGAAFSSSSESGVTTTIAILCHEIPHEMGDFAVLLSS 558 + + + L D HNF DGLAIGA+F G+ TT+ +L HE+PHE+GDFA+L+ S Sbjct: 314 DLRVSGYLNLAADLAHNFTDGLAIGASFRGGRGLGILTTMTVLLHEVPHEVGDFAILVQS 373 Query: 559 GLSMKTAILMNFISSLTAFMGLYIGL--------SVSADPCVQDWIFTVTAGMFLYLSLV 610 G S K A+ + ++++ A G L S A W+ TAG F+Y++ V Sbjct: 374 GCSKKQAMRLQLLTAVGALAGTACALLTEGGAVGSEIAGGAGPGWVLPFTAGGFIYVATV 433 Query: 611 EMLPEMTHVQTQRPWMMFLLQNFGLILGWLSLLLLAIYE 649 +LPE+ + + LL+ GL+ G + ++L+A E Sbjct: 434 SVLPELLREASP---LQSLLEVLGLLGGVIMMVLIAHLE 469 >gi|40255101 solute carrier family 39 (zinc transporter), member 13 isoform b [Homo sapiens] Length = 364 Score = 103 bits (258), Expect = 4e-22 Identities = 77/268 (28%), Positives = 134/268 (50%), Gaps = 31/268 (11%) Query: 401 LQLFVGLAVGTLSGDALLHLIPQVLGLHKQEAPEFGHFHESKGHIWKL-MGLIGGIHGFF 459 L+ + A+G L G+ LHL+P+ +P G +S +L + +I GI F Sbjct: 106 LKQLLSFALGGLLGNVFLHLLPEAWAYTCSASP--GGEGQSLQQQQQLGLWVIAGILTFL 163 Query: 460 LIEKCFILLVSPNDKKSPEDSQ----------------AAEMPIGSMTASNRKCKAISLL 503 +EK F+ ++P AAE +G++ S + ++LL Sbjct: 164 ALEKMFLDSKEEGTSQAPNKDPTAAAAALNGGHCLAQPAAEPGLGAVVRSIKVSGYLNLL 223 Query: 504 AIMILVGDSLHNFADGLAIGAAFSSSSESGVTTTIAILCHEIPHEMGDFAVLLSSGLSMK 563 A +++ NF GLA+ A+F S + G+ TT+AIL HEIPHE+GDFA+LL +G Sbjct: 224 A------NTIDNFTHGLAVAASFLVSKKIGLLTTMAILLHEIPHEVGDFAILLRAGFDRW 277 Query: 564 TAILMNFISSLTAFMGLYIGLSVSADPCVQD---WIFTVTAGMFLYLSLVEMLPEMTHVQ 620 +A + ++L +G + + V++ W+ T+G FLY++LV +LP++ ++ Sbjct: 278 SAAKLQLSTALGGLLGAGFAICTQSPKGVEETAAWVLPFTSGGFLYIALVNVLPDL--LE 335 Query: 621 TQRPWMMFLLQNFGLILGWLSLLLLAIY 648 + PW L Q L G + ++L +++ Sbjct: 336 EEDPWRS-LQQLLLLCAGIVVMVLFSLF 362 >gi|190014617 solute carrier family 39 (zinc transporter), member 13 isoform a [Homo sapiens] Length = 371 Score = 101 bits (251), Expect = 2e-21 Identities = 78/275 (28%), Positives = 134/275 (48%), Gaps = 38/275 (13%) Query: 401 LQLFVGLAVGTLSGDALLHLIPQVLGLHKQEAPEFGHFHESKGHIWKL-MGLIGGIHGFF 459 L+ + A+G L G+ LHL+P+ +P G +S +L + +I GI F Sbjct: 106 LKQLLSFALGGLLGNVFLHLLPEAWAYTCSASP--GGEGQSLQQQQQLGLWVIAGILTFL 163 Query: 460 LIEKCFILLVSPNDKKSPEDSQ----------------AAEMPIGSMTASNRKCKAISLL 503 +EK F+ ++P AAE +G++ S + ++LL Sbjct: 164 ALEKMFLDSKEEGTSQAPNKDPTAAAAALNGGHCLAQPAAEPGLGAVVRSIKVSGYLNLL 223 Query: 504 AIMILVGDSLHNFADGLAIGAAFSSSSESGVTTTIAILCHEIPHEMGDFAVLLSSGLSMK 563 A +++ NF GLA+ A+F S + G+ TT+AIL HEIPHE+GDFA+LL +G Sbjct: 224 A------NTIDNFTHGLAVAASFLVSKKIGLLTTMAILLHEIPHEVGDFAILLRAGFDRW 277 Query: 564 TAILMNFISSLTAFMGLYIGLS-------VSADPCVQD---WIFTVTAGMFLYLSLVEML 613 +A + ++L +G + V P ++ W+ T+G FLY++LV +L Sbjct: 278 SAAKLQLSTALGGLLGAGFAICTQSPKGVVGCSPAAEETAAWVLPFTSGGFLYIALVNVL 337 Query: 614 PEMTHVQTQRPWMMFLLQNFGLILGWLSLLLLAIY 648 P++ ++ + PW L Q L G + ++L +++ Sbjct: 338 PDL--LEEEDPWRS-LQQLLLLCAGIVVMVLFSLF 369 >gi|40254928 solute carrier family 39 (zinc transporter), member 9 [Homo sapiens] Length = 307 Score = 58.9 bits (141), Expect = 1e-08 Identities = 83/323 (25%), Positives = 143/323 (44%), Gaps = 63/323 (19%) Query: 372 VAVTLLTLGSMLGTALVLFHSCEENY-RLILQLFVGLAVGTLSGDALLHLIPQVL----- 425 ++++LL+L ++G + N+ L+L L G L G AL ++P+ + Sbjct: 5 ISISLLSLAMLVGCYVAGIIPLAVNFSEERLKLVTVLGAGLLCGTALAVIVPEGVHALYE 64 Query: 426 ----GLHKQEAPEFG-------------HFHESKGHIWKLMGLIGG--IHGFFLIEKCFI 466 G H Q + H HE +L IG + GF F+ Sbjct: 65 DILEGKHHQASETHNVIASDKAAEKSVVHEHEHSHDHTQLHAYIGVSLVLGFV-----FM 119 Query: 467 LLVSP---NDKKSPEDSQAAEMPIGSMTASNRKCKAISLLAIMILVGDSLHNFADGLAIG 523 LLV + S +D +AA +SN K I +G +H ADG+A+G Sbjct: 120 LLVDQIGNSHVHSTDDPEAAR-------SSNSK--------ITTTLGLVVHAAADGVALG 164 Query: 524 AAFSSSSES-GVTTTIAILCHEIPHEMGDFAVLLSSGLS---MKTAILMNFISSLTAFMG 579 AA S+S S + +AI+ H+ P G + L+ +GL ++ +L+ +++ M Sbjct: 165 AAASTSQTSVQLIVFVAIMLHKAPAAFGLVSFLMHAGLERNRIRKHLLVFALAAPVMSMV 224 Query: 580 LYIGLSVSADPCVQDWIFT-----VTAGMFLYLSLVEMLPEMTHV-QTQRPWM-----MF 628 Y+GLS S+ + + T +AG FLY++ V +LPE+ + + +P + Sbjct: 225 TYLGLSKSSKEALSEVNATGVAMLFSAGTFLYVATVHVLPEVGGIGHSHKPDATGGRGLS 284 Query: 629 LLQNFGLILGWLSLLLLAIYEQN 651 L+ L+LG L L+L++ Q+ Sbjct: 285 RLEVAALVLGCLIPLILSVGHQH 307 >gi|156415986 solute carrier family 39 (zinc transporter), member 2 [Homo sapiens] Length = 309 Score = 45.8 bits (107), Expect = 1e-04 Identities = 34/119 (28%), Positives = 61/119 (51%), Gaps = 8/119 (6%) Query: 502 LLAIMILVGDSLHNFADGLAIGAAFSSSSESGVTTTIAILCHEIPHEMGDFAVLLSSGLS 561 L A+++L+ S H+ +GLA+G + + V +A+L H+ G L+ G S Sbjct: 163 LRALVLLLSLSFHSVFEGLAVG--LQPTVAATVQLCLAVLAHKGLVVFGVGMRLVHLGTS 220 Query: 562 MKTAILMNFISSLTAFMGLYIGLSVSADPC------VQDWIFTVTAGMFLYLSLVEMLP 614 + A+ + +L + +GL +GL+V+ Q + V AG FLY++ +E+LP Sbjct: 221 SRWAVFSILLLALMSPLGLAVGLAVTGGDSEGGRGLAQAVLEGVAAGTFLYVTFLEILP 279 >gi|21361423 solute carrier family 39 (zinc transporter), member 1 [Homo sapiens] Length = 324 Score = 42.0 bits (97), Expect = 0.002 Identities = 47/204 (23%), Positives = 86/204 (42%), Gaps = 22/204 (10%) Query: 457 GFFLIEKCFILLVSPNDKKSPEDSQAAEMPIGSMT--------------ASNRKCKAISL 502 GFFL+ + ++ ++ P + +G++ AS +L Sbjct: 119 GFFLVLVMEQITLAYKEQSGPSPLEETRALLGTVNGGPQHWHDGPGVPQASGAPATPSAL 178 Query: 503 LAIMILVGDSLHNFADGLAIGAAFSSSSESGVTTTIAILCHEIPHEMGDFAVLLSSGLSM 562 A +++ +LH+ +GLA+G + +A+L H+ + LL S L Sbjct: 179 RACVLVFSLALHSVFEGLAVG--LQRDRARAMELCLALLLHKGILAVSLSLRLLQSHLRA 236 Query: 563 KTAILMNFISSLTAFMGLYIG--LSVSADPC---VQDWIFTVTAGMFLYLSLVEMLPEMT 617 + + S +G+ +G L+ SA P Q + + AG FLY++ +E+LP+ Sbjct: 237 QVVAGCGILFSCMTPLGIGLGAALAESAGPLHQLAQSVLEGMAAGTFLYITFLEILPQEL 296 Query: 618 HVQTQRPW-MMFLLQNFGLILGWL 640 QR ++ LL F L+ G L Sbjct: 297 ASSEQRILKVILLLAGFALLTGLL 320 >gi|229577422 solute carrier family 39, member 11 isoform 1 [Homo sapiens] Length = 342 Score = 34.3 bits (77), Expect = 0.37 Identities = 25/118 (21%), Positives = 50/118 (42%), Gaps = 8/118 (6%) Query: 506 MILVGDSLHNFADGLAIGAAF-------SSSSESGVTTTIAILCHEIPHEMGDFAVLLSS 558 ++++ ++HN +GLA+G F S++ ES I I P + L + Sbjct: 196 LLILAITIHNVPEGLAVGVGFGAIEKTASATFESARNLAIGIGIQNFPEGLAVSLPLRGA 255 Query: 559 GLSMKTAILMNFISSLT-AFMGLYIGLSVSADPCVQDWIFTVTAGMFLYLSLVEMLPE 615 G S A +S + G++ +V + + AG +Y+ + +++PE Sbjct: 256 GFSTWRAFWYGQLSGMVEPLAGVFGAFAVVLAEPILPYALAFAAGAMVYVVMDDIIPE 313 >gi|229577418 solute carrier family 39, member 11 isoform 2 [Homo sapiens] Length = 335 Score = 34.3 bits (77), Expect = 0.37 Identities = 25/118 (21%), Positives = 50/118 (42%), Gaps = 8/118 (6%) Query: 506 MILVGDSLHNFADGLAIGAAF-------SSSSESGVTTTIAILCHEIPHEMGDFAVLLSS 558 ++++ ++HN +GLA+G F S++ ES I I P + L + Sbjct: 189 LLILAITIHNVPEGLAVGVGFGAIEKTASATFESARNLAIGIGIQNFPEGLAVSLPLRGA 248 Query: 559 GLSMKTAILMNFISSLT-AFMGLYIGLSVSADPCVQDWIFTVTAGMFLYLSLVEMLPE 615 G S A +S + G++ +V + + AG +Y+ + +++PE Sbjct: 249 GFSTWRAFWYGQLSGMVEPLAGVFGAFAVVLAEPILPYALAFAAGAMVYVVMDDIIPE 306 >gi|205360987 TBP-associated factor 1B [Homo sapiens] Length = 588 Score = 32.3 bits (72), Expect = 1.4 Identities = 29/118 (24%), Positives = 47/118 (39%), Gaps = 23/118 (19%) Query: 276 RKQNNIITHDQDYSNFSSSMEKESEDGPVSW---------DQTCFSARQLVEIFLQKGLS 326 +K+ ++ + +S S + P S+ D+TCF L + +KG S Sbjct: 445 KKREMVVNLQKQFSTLVESTATAGKKSPSSFQFNWTEEDTDRTCFHGHSLQGVLKEKGQS 504 Query: 327 LISKEDFKQMSPGIIQQLLSCSC-HLPKDQQAKLPPTTLEKYGYSTVAVTLLTLGSML 383 L++K +S Q+ C C H+ TT E+ YS +L L S L Sbjct: 505 LLTKNSLYWLS---TQKFCRCYCTHV----------TTYEESNYSLSYQFILNLFSFL 549 >gi|168480072 BCL2-related protein A1 isoform 2 [Homo sapiens] Length = 163 Score = 32.0 bits (71), Expect = 1.8 Identities = 20/61 (32%), Positives = 35/61 (57%), Gaps = 8/61 (13%) Query: 280 NIITHDQDYSNFSSSMEKESEDGPVSWDQTCFSARQLVEIFLQKGLSLISKEDFKQMSPG 339 N+++ D + F+ MEKE EDG ++W ++V IF +G+ LI K +Q++P Sbjct: 60 NVVSVDTARTLFNQVMEKEFEDGIINWG-------RIVTIFAFEGI-LIKKLLRQQIAPD 111 Query: 340 I 340 + Sbjct: 112 V 112 >gi|4757840 BCL2-related protein A1 isoform 1 [Homo sapiens] Length = 175 Score = 32.0 bits (71), Expect = 1.8 Identities = 20/61 (32%), Positives = 35/61 (57%), Gaps = 8/61 (13%) Query: 280 NIITHDQDYSNFSSSMEKESEDGPVSWDQTCFSARQLVEIFLQKGLSLISKEDFKQMSPG 339 N+++ D + F+ MEKE EDG ++W ++V IF +G+ LI K +Q++P Sbjct: 60 NVVSVDTARTLFNQVMEKEFEDGIINWG-------RIVTIFAFEGI-LIKKLLRQQIAPD 111 Query: 340 I 340 + Sbjct: 112 V 112 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.321 0.135 0.396 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 23,778,194 Number of Sequences: 37866 Number of extensions: 1025486 Number of successful extensions: 2776 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 25 Number of HSP's successfully gapped in prelim test: 12 Number of HSP's that attempted gapping in prelim test: 2659 Number of HSP's gapped (non-prelim): 62 length of query: 654 length of database: 18,247,518 effective HSP length: 109 effective length of query: 545 effective length of database: 14,120,124 effective search space: 7695467580 effective search space used: 7695467580 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.