Guide to the Human Genome
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Search of human proteins with 223633890

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|223633890 hypothetical protein LOC729956 [Homo sapiens]
         (538 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|223633890 hypothetical protein LOC729956 [Homo sapiens]           1120   0.0  
gi|211904177 hypothetical protein LOC388336 [Homo sapiens]            238   8e-63
gi|223633980 hypothetical protein LOC729993 isoform 1 [Homo sapi...   148   1e-35
gi|113429443 PREDICTED: transmembrane protein 46-like [Homo sapi...   136   4e-32
gi|169215850 PREDICTED: transmembrane protein 46-like [Homo sapi...   135   9e-32
gi|223633982 hypothetical protein LOC729993 isoform 2 [Homo sapi...   116   5e-26
gi|154355000 KH-type splicing regulatory protein [Homo sapiens]        62   1e-09
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo...    59   1e-08
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ...    59   1e-08
gi|122937450 shisa homolog 3 [Homo sapiens]                            56   7e-08
gi|56090523 shisa homolog 2 [Homo sapiens]                             56   7e-08
gi|73427806 v-maf musculoaponeurotic fibrosarcoma oncogene homol...    50   5e-06
gi|5453736 v-maf musculoaponeurotic fibrosarcoma oncogene homolo...    50   5e-06
gi|15011916 nucleolar protein family A, member 1 [Homo sapiens]        50   5e-06
gi|9506713 nucleolar protein family A, member 1 [Homo sapiens]         50   5e-06
gi|4502565 calpain, small subunit 1 [Homo sapiens]                     49   9e-06
gi|51599151 calpain, small subunit 1 [Homo sapiens]                    49   9e-06
gi|53829370 neuralized homolog 4 isoform 1 [Homo sapiens]              48   2e-05
gi|53829368 neuralized homolog 4 isoform 2 [Homo sapiens]              48   2e-05
gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2 ...    48   2e-05
gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1 ...    48   2e-05
gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3 ...    48   2e-05
gi|109452587 family with sequence similarity 98, member B isofor...    48   3e-05
gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sap...    48   3e-05
gi|4885597 sine oculis homeobox homolog 3 [Homo sapiens]               47   3e-05
gi|153792074 proline rich 12 [Homo sapiens]                            47   3e-05
gi|13994190 frizzled 8 [Homo sapiens]                                  47   6e-05
gi|221219000 phospholipase C-like 2 isoform 1 [Homo sapiens]           47   6e-05
gi|110347449 POU domain, class 4, transcription factor 1 [Homo s...    47   6e-05
gi|33620755 YEATS domain containing 2 [Homo sapiens]                   46   1e-04

>gi|223633890 hypothetical protein LOC729956 [Homo sapiens]
          Length = 538

 Score = 1120 bits (2898), Expect = 0.0
 Identities = 538/538 (100%), Positives = 538/538 (100%)

Query: 1   MPALLLLVLLASSAGQARARPSNATSAEPAGPLPALLAHLRRLTGALTGGGGAASPGANG 60
           MPALLLLVLLASSAGQARARPSNATSAEPAGPLPALLAHLRRLTGALTGGGGAASPGANG
Sbjct: 1   MPALLLLVLLASSAGQARARPSNATSAEPAGPLPALLAHLRRLTGALTGGGGAASPGANG 60

Query: 61  TRTGPAGGAGAAARAPPPAELCHGYYDVMGQYDATFNCSTGSYRFCCGTCHYRFCCEHRH 120
           TRTGPAGGAGAAARAPPPAELCHGYYDVMGQYDATFNCSTGSYRFCCGTCHYRFCCEHRH
Sbjct: 61  TRTGPAGGAGAAARAPPPAELCHGYYDVMGQYDATFNCSTGSYRFCCGTCHYRFCCEHRH 120

Query: 121 MRLAQASCSNYDTPRWATTPPPLAGGAGGAGGAGGGPGPGQAGWLEGGRTGGAGGRGGEG 180
           MRLAQASCSNYDTPRWATTPPPLAGGAGGAGGAGGGPGPGQAGWLEGGRTGGAGGRGGEG
Sbjct: 121 MRLAQASCSNYDTPRWATTPPPLAGGAGGAGGAGGGPGPGQAGWLEGGRTGGAGGRGGEG 180

Query: 181 PGGSTAYVVCGVISFALAVGVGAKVAFSKASRAPRAHRDINVPRALVDILRHQAGPGTRP 240
           PGGSTAYVVCGVISFALAVGVGAKVAFSKASRAPRAHRDINVPRALVDILRHQAGPGTRP
Sbjct: 181 PGGSTAYVVCGVISFALAVGVGAKVAFSKASRAPRAHRDINVPRALVDILRHQAGPGTRP 240

Query: 241 DRARSSSLTPGIGGPDSMPPRTPKNLYNTVKTPNLDWRALPPPSPSLHYSTLSCSRSFHN 300
           DRARSSSLTPGIGGPDSMPPRTPKNLYNTVKTPNLDWRALPPPSPSLHYSTLSCSRSFHN
Sbjct: 241 DRARSSSLTPGIGGPDSMPPRTPKNLYNTVKTPNLDWRALPPPSPSLHYSTLSCSRSFHN 300

Query: 301 LSHLPPSYEAAVKSELNRYSSLKRLAEKDLDEAYLKRRPLELPRGTLPLHALRRPGTGGG 360
           LSHLPPSYEAAVKSELNRYSSLKRLAEKDLDEAYLKRRPLELPRGTLPLHALRRPGTGGG
Sbjct: 301 LSHLPPSYEAAVKSELNRYSSLKRLAEKDLDEAYLKRRPLELPRGTLPLHALRRPGTGGG 360

Query: 361 YRMEAWGGPEELGLAPAPNPRRVMSQEHLLGDGGRSRYEFTLPRARLVSQEHLLLSSPEA 420
           YRMEAWGGPEELGLAPAPNPRRVMSQEHLLGDGGRSRYEFTLPRARLVSQEHLLLSSPEA
Sbjct: 361 YRMEAWGGPEELGLAPAPNPRRVMSQEHLLGDGGRSRYEFTLPRARLVSQEHLLLSSPEA 420

Query: 421 LRQSREHLLSPPRSPALPPDPTARASLAASHSNLLLGPGGPPTPLRGLPPPSSLHAHHHH 480
           LRQSREHLLSPPRSPALPPDPTARASLAASHSNLLLGPGGPPTPLRGLPPPSSLHAHHHH
Sbjct: 421 LRQSREHLLSPPRSPALPPDPTARASLAASHSNLLLGPGGPPTPLRGLPPPSSLHAHHHH 480

Query: 481 ALHGSPQPAWMSDAGGGGGTLARRPPFQRQGTLEQLQFIPGHHLPQHLRTASKNEVTV 538
           ALHGSPQPAWMSDAGGGGGTLARRPPFQRQGTLEQLQFIPGHHLPQHLRTASKNEVTV
Sbjct: 481 ALHGSPQPAWMSDAGGGGGTLARRPPFQRQGTLEQLQFIPGHHLPQHLRTASKNEVTV 538


>gi|211904177 hypothetical protein LOC388336 [Homo sapiens]
          Length = 551

 Score =  238 bits (608), Expect = 8e-63
 Identities = 213/613 (34%), Positives = 277/613 (45%), Gaps = 145/613 (23%)

Query: 4   LLLLVLLA-------SSAGQARARPSNATSAEPAGPLPALLAHLRRLTGALTGGGG---- 52
           LLLL+LL+        S   AR R +N T +     +       RR  GAL  GG     
Sbjct: 6   LLLLLLLSLESLDLLPSVHGARGRAANRTLSAGGAAVGG-----RRAGGALARGGRELNG 60

Query: 53  -AASPG---ANGTRTGPAGGAGAAARAPPPAELCHGYYDVMGQYDATFNC--STGSYRFC 106
            A +PG   A   R  PA    AAA A    E C GYYDV GQYD  F C  S   Y +C
Sbjct: 61  TARAPGIPEAGSRRGQPAAAVAAAASAAVTYETCWGYYDVSGQYDKEFECNNSESGYLYC 120

Query: 107 CGTCHYRFCCEHRHMRLAQASCSNYDTPRWATTPPPLAGGAGGAGGAGGGPGPGQAGWLE 166
           CGTC+YRFCC+ RH +L Q  C+NY +P W  TP                PGP      E
Sbjct: 121 CGTCYYRFCCKKRHEKLDQRQCTNYQSPVWVQTPSTKV----------VSPGPENKYDPE 170

Query: 167 GGRTGGAGGRGGEGPGGSTAYVVCGVISFALAVGVGAKVAFSKASRAPRAHRDINVPRAL 226
             +T              T Y+ CGVI+F +  GV AKV++ KA R P   R++N+ RAL
Sbjct: 171 KDKT------------NFTVYITCGVIAFVIVAGVFAKVSYDKAHRPP---REMNIHRAL 215

Query: 227 VDILRHQAGP--------------GTRPDR--------------ARSSSLTPGIGGPDSM 258
            DILR Q GP               T P                 R++  TPG  G D+ 
Sbjct: 216 ADILRQQ-GPIPIAHCERETISAIDTSPKENTPVRSSSKNHYTPVRTAKQTPGHYGKDAY 274

Query: 259 PPRTPKNLYNTVKT------------------PNLDWRALPPPSPSLHYST--------- 291
               P +L+N + +                  P L      PP      +          
Sbjct: 275 RSGGP-DLHNFISSGFVTLGRGHTKGDHQYNHPILSSVTQIPPHEKPRMNNILTSATEPY 333

Query: 292 -LSCSRSFHNLSHLPPSYEAAVKSELNRYSSLKRLAEKDLDEAYLKRRPLE--LPRGTLP 348
            LS SRSF NL+HLPPSYE+AVK+  ++YSSLKRL +K+ DE Y++RR L     RGTLP
Sbjct: 334 DLSFSRSFQNLAHLPPSYESAVKTNPSKYSSLKRLTDKEADEYYMRRRHLPDLAARGTLP 393

Query: 349 LHALRRPGTGGGYRMEAWGGPEELGLAPAPNPRRVMSQEHLLGDGGRSRYEFTLPRARLV 408
           L+ ++                + L       P R MSQ+ +L        EF++P  R++
Sbjct: 394 LNVIQ------------MSQQKPLPRERPRRPIRAMSQDRVLSPDRGLPDEFSMPYDRIL 441

Query: 409 SQEHLLLSSPEALRQSREHLLSPPRSPALPPDPTARASLAASHSNLLLGPGGPPTPLRGL 468
           S E LL  S E L  S++ LLSP R+ A P    +R   A SH+++ +      TP+   
Sbjct: 442 SDEQLL--STERL-HSQDPLLSPERT-AFPEQSLSR---AISHTDVFVS-----TPVLDR 489

Query: 469 PPPSSLHAHHHHALHGSPQPAWMSDAG-GGGGTLARRPPF--QRQGTLEQLQFIPGHHLP 525
              S +H+H        P  +  S A  G   T A+R  F  +R  T+EQL +IPGHH  
Sbjct: 490 YRMSKMHSH--------PSASNNSYATLGQSQTAAKRHAFASRRHNTVEQLHYIPGHHT- 540

Query: 526 QHLRTASKNEVTV 538
               TASK EVTV
Sbjct: 541 --CYTASKTEVTV 551


>gi|223633980 hypothetical protein LOC729993 isoform 1 [Homo
           sapiens]
          Length = 465

 Score =  148 bits (374), Expect = 1e-35
 Identities = 106/333 (31%), Positives = 148/333 (44%), Gaps = 55/333 (16%)

Query: 40  LRRLTGALTGGGGAASPGANGTRTGPAGGAGAAARAPPPAELCHGYYDVMGQYDATFNCS 99
           L +L G L   GG  S  A+G  +  A  + A     P  + C GY+DVMGQ+D  FNCS
Sbjct: 73  LAQLGGVLLLAGGNRSGAASGEASEGAEASDAPPTRAPTPDFCRGYFDVMGQWDPPFNCS 132

Query: 100 TGSYRFCCGTCHYRFCCEHRHMRLAQASCSNYDTPRWATTPPPLAGGAGGAGGAGGGPGP 159
           +G + FCCGTC +RFCC  +  RL Q++C+NYDTP W  T  P A               
Sbjct: 133 SGDFIFCCGTCGFRFCCTFKKRRLNQSTCTNYDTPLWLNTGKPPA--------------- 177

Query: 160 GQAGWLEGGRTGGAGGRGGEGPGGSTAYVVCGVISFALAVGVGAKVAFSKASRAPRAHRD 219
                    R         +       Y++CGV++  + VG+  K+   KA R  R H  
Sbjct: 178 ---------RKDDPLHDPTKDKTNLIVYIICGVVAVMVLVGIFTKLGLEKAHRPQREH-- 226

Query: 220 INVPRALVDILRHQAGPGTRPDRARSSSLTPGIGGPDSMPPRTPKNLYNTVKTPNLDWRA 279
             + RAL D++R Q G        R  ++   +   ++M  RTP N  +  +  N     
Sbjct: 227 --MSRALADVMRPQ-GHCNTDHMERDLNIVVHVQHYENMDTRTPINNLHATQMNN----- 278

Query: 280 LPPPSPSLHYSTLSCSRSFHNLSHLPPSYEAAVK-SELNRYSSLKRL------------- 325
             P SP L    +    S+ NL  +   YE      ELN+Y+SLK +             
Sbjct: 279 AVPTSPLL--QQMGHPHSYPNLGQISNPYEQQPPGKELNKYASLKAVGSSDGDWAVSTLK 336

Query: 326 ---AEKDLDEAYLKRRPLE--LPRGTLPLHALR 353
              A+K  D+ Y KRR L     +G LPLH +R
Sbjct: 337 SPKADKVNDDFYTKRRHLAELAAKGNLPLHPVR 369


>gi|113429443 PREDICTED: transmembrane protein 46-like [Homo
           sapiens]
          Length = 492

 Score =  136 bits (343), Expect = 4e-32
 Identities = 154/530 (29%), Positives = 207/530 (39%), Gaps = 98/530 (18%)

Query: 40  LRRLTGALTGGGGAASPGANGTRTGPAGGAGAAARAPPPAELCHGYYDVMGQYDATFNCS 99
           L R      G   A  P A GT T P GG           + C GYYDVMGQ+D  FNCS
Sbjct: 30  LARPPSGRAGAPEAQGPAAPGT-TAPEGG-----------DRCRGYYDVMGQWDPPFNCS 77

Query: 100 TGSYRFCCGTCHYRFCCEHRHMRLAQASCSNYDTPRWATTPPPLAGGAGGAGGAGGGPGP 159
           +G+Y FCCGTC YRFCC     RL Q+ CSNYDTP W  T  P                P
Sbjct: 78  SGAYSFCCGTCGYRFCCHDGPRRLDQSRCSNYDTPAWVQTGRP----------------P 121

Query: 160 GQAGWLEGGRTGGAGGRGGEGPGGSTAYVVCGVISFALAVGVGAKVAFSKASRAPRAHRD 219
            +A      R   A    G     +  Y VCGV +  +  G+GA++   +A  +PRA R 
Sbjct: 122 ARA------RDTAAPRDPGRERSHTAVYAVCGVAALLVLAGIGARLGLERA-HSPRARR- 173

Query: 220 INVPRALVDILRHQAGPGTRPDRARSSSLTPGIGG------PDSMPPRTPKNLYNTVKTP 273
             V RAL ++L+    PG  P      +L P +GG       D +P  +P N     +TP
Sbjct: 174 -TVTRALTELLKQ---PG--PQEPLPPTLGPPLGGCVQVQMGDGLPRGSPHNSAGP-RTP 226

Query: 274 NLDWRALPPPSPSLHYSTLSCSRSFHNLSHLPPSYEAAVKSELNRYSSLKRLAEKDLDEA 333
            L  RA PP  P +  +              PP   AA  +  +    +        D  
Sbjct: 227 RLA-RASPPGEPFMRVA--------------PPGLAAAAAARDSEPGPVPGAGGCGEDRL 271

Query: 334 YLKRRPLELPRG---TLPLHALRRPGTGGGYRMEAWGGPEELGLAPAPNPRRVMSQEHLL 390
             + RP   P G   T     LRR  + GG       GP  + L  AP+ +R+ +     
Sbjct: 272 GSQPRPENGPPGSHRTASGRGLRRGDSEGGVNRGI--GPSRVSLL-APDKKRLNNAPRGS 328

Query: 391 GDGGRSRYEFTLPRARLVSQEHLLLSSPEALRQSREHLLSP----PRSPALPPDPTARAS 446
              G  R         L  Q      +       +    +P     R PAL P P    +
Sbjct: 329 AAPGPPRGPRLQGGGSLTLQPDYAKYATFKAAALKAAEAAPRDFCQRFPALEPSPRQPPA 388

Query: 447 LAASHSNLLLGPGGPPTPLRGLP-------PPSSLHAHHHHALHGSPQPAWMSDAGGGGG 499
            A   S  L      P PL   P       PP++   +         +PA +S       
Sbjct: 389 RAPRPSPDL------PAPLDACPWAPPVYAPPAAPGPYAAWTSSRPARPAPLSHPTARAF 442

Query: 500 TLARRP--PFQRQGTLEQLQF----IPGHH-----LPQHLRTASKNEVTV 538
            + RRP    +RQ +++  +     +PG +       ++LRT SK EVTV
Sbjct: 443 QVPRRPGHAARRQFSVKMPETFNPQLPGLYGSAGRGSRYLRTNSKTEVTV 492


>gi|169215850 PREDICTED: transmembrane protein 46-like [Homo
           sapiens]
          Length = 547

 Score =  135 bits (340), Expect = 9e-32
 Identities = 115/353 (32%), Positives = 148/353 (41%), Gaps = 70/353 (19%)

Query: 40  LRRLTGALTGGGGAASPGANGTRTGPAGGAGAAARAPPPAELCHGYYDVMGQYDATFNCS 99
           L R      G   A  P A GT T P GG           + C GYYDVMGQ+D  FNCS
Sbjct: 30  LARPPSGRAGAPEAQGPAAPGT-TAPEGG-----------DRCRGYYDVMGQWDPPFNCS 77

Query: 100 TGSYRFCCGTCHYRFCCEHRHMRLAQASCSNYDTPRWATTPPPLAGGAGGAGGAGGGPGP 159
           +G+Y FCCGTC YRFCC     RL Q+ CSNYDTP W  T  P                P
Sbjct: 78  SGAYSFCCGTCGYRFCCHDGPRRLDQSRCSNYDTPAWVQTGRP----------------P 121

Query: 160 GQAGWLEGGRTGGAGGRGGEGPGGSTAYVVCGVISFALAVGVGAKVAFSKASRAPRAHRD 219
            +A      R   A    G     +  Y VCGV +  +  G+GA++   +A  +PRA R 
Sbjct: 122 ARA------RDTAAPRDPGRERSHTAVYAVCGVAALLVLAGIGARLGLERA-HSPRARR- 173

Query: 220 INVPRALVDILRHQAGPGTRPDRARSSSLTPGIGG------PDSMPPRTPKNLYNTVKTP 273
             V RAL ++L+    PG  P      +L P +GG       D +P  +P N     +TP
Sbjct: 174 -TVTRALTELLKQ---PG--PQEPLPPTLGPPLGGCVQVQMGDGLPRGSPHNSAGP-RTP 226

Query: 274 NLDWRALPPPSPSLHYSTLSCSRSFHNLSHLPPSYEAAVKSELNRYSSLKRLAEKDLDEA 333
            L  RA PP  P +  +              PP   AA  +  +    +        D  
Sbjct: 227 RLA-RASPPGEPFMRVA--------------PPGLAAAAAARDSEPGPVPGAGGCGEDRL 271

Query: 334 YLKRRPLELPRG---TLPLHALRRPGTGGGYRMEAWGGPEELGLAPAPNPRRV 383
             + RP   P G   T     LRR  + GG       GP  + L  AP+ +R+
Sbjct: 272 GSQPRPENGPPGSHRTASGRGLRRGDSEGGVNRGI--GPSRVSLL-APDKKRL 321


>gi|223633982 hypothetical protein LOC729993 isoform 2 [Homo
           sapiens]
          Length = 262

 Score =  116 bits (291), Expect = 5e-26
 Identities = 62/178 (34%), Positives = 84/178 (47%), Gaps = 24/178 (13%)

Query: 40  LRRLTGALTGGGGAASPGANGTRTGPAGGAGAAARAPPPAELCHGYYDVMGQYDATFNCS 99
           L +L G L   GG  S  A+G  +  A  + A     P  + C GY+DVMGQ+D  FNCS
Sbjct: 73  LAQLGGVLLLAGGNRSGAASGEASEGAEASDAPPTRAPTPDFCRGYFDVMGQWDPPFNCS 132

Query: 100 TGSYRFCCGTCHYRFCCEHRHMRLAQASCSNYDTPRWATTPPPLAGGAGGAGGAGGGPGP 159
           +G + FCCGTC +RFCC  +  RL Q++C+NYDTP W  T  P A               
Sbjct: 133 SGDFIFCCGTCGFRFCCTFKKRRLNQSTCTNYDTPLWLNTGKPPA--------------- 177

Query: 160 GQAGWLEGGRTGGAGGRGGEGPGGSTAYVVCGVISFALAVGVGAKVAFSKASRAPRAH 217
                    R         +       Y++CGV++  + VG+  K+   KA R  R H
Sbjct: 178 ---------RKDDPLHDPTKDKTNLIVYIICGVVAVMVLVGIFTKLGLEKAHRPQREH 226


>gi|154355000 KH-type splicing regulatory protein [Homo sapiens]
          Length = 711

 Score = 62.4 bits (150), Expect = 1e-09
 Identities = 34/58 (58%), Positives = 36/58 (62%), Gaps = 4/58 (6%)

Query: 129 SNYDTPRWATTPPPLAGGAGGAGGAGGGPGPGQAGWLEGGRTGGAGGRGGEGPGGSTA 186
           S+Y T      PPP AGG GGAGGAGGGP PG  G   G R  G GG GG GPGG +A
Sbjct: 2   SDYSTGGPPPGPPPPAGGGGGAGGAGGGPPPGPPG--AGDR--GGGGPGGGGPGGGSA 55


>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
           sapiens]
          Length = 503

 Score = 58.5 bits (140), Expect = 1e-08
 Identities = 106/388 (27%), Positives = 127/388 (32%), Gaps = 90/388 (23%)

Query: 141 PPLAGGAGGAGGAGGGPGPGQAGWLEGGRTGGAGGRGGEGPGGSTAYVVCGVISFALAVG 200
           P  AG  GG GG GGG G G      GG  GG G  GG GP G       G+        
Sbjct: 62  PKGAGAGGGGGGFGGGGGFG-----GGGGGGGGGSFGGGGPPGLGGLFQAGMPKLRSTAN 116

Query: 201 VGAKVAFSKASRAPRAHRDINVP---------RALVDILRHQAGPGTRPDRARSSSLTPG 251
                  S+    P   R  +           R  V    H++GP   P R R     P 
Sbjct: 117 RDNDSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGP-PEPQRNRMPPPRPD 175

Query: 252 IGG-PDSMPPRTPKNLYNTVKTPNLDWRALPP-------PSP------------------ 285
           +G  PDS+PP  P        +P+   R  PP       PSP                  
Sbjct: 176 VGSKPDSIPPPVPSTPRPIQSSPHN--RGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGG 233

Query: 286 SLHYSTLSCSRSFHNLSHLPPSYEAAVKSELNRYSSLKRLAEKDLDEAYLKRRPLELPRG 345
           S+  S LS S  F N   LPP+   A                  LD+   K  P   P G
Sbjct: 234 SIRQSPLSSSSPFSNRPPLPPTPSRA------------------LDD---KPPPPPPPVG 272

Query: 346 TLPLHALRR------PGTGGGYRMEAWGGPEELGLAPAPNPRRVMSQEHLLGDGGRSRYE 399
             P  ++ R      P       + +   P     AP P P         L        E
Sbjct: 273 NRP--SIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDE 330

Query: 400 FTLPRARLVSQEHLLLSSPEALRQSREHLLSPPRSPALPPDPTARASLAASHSNLLLGPG 459
              PR   + Q +L LSS      S   L SP RS  LPP P+ R            G  
Sbjct: 331 --TPR---LPQRNLSLSS------STPPLPSPGRSGPLPPPPSERPPPPVRDPP---GRS 376

Query: 460 GPPTPLRGLPPPSSLHAHHHHALHGSPQ 487
           GP  P    PPP S +     AL  +PQ
Sbjct: 377 GPLPP----PPPVSRNGSTSRALPATPQ 400


>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
           sapiens]
          Length = 503

 Score = 58.5 bits (140), Expect = 1e-08
 Identities = 106/388 (27%), Positives = 127/388 (32%), Gaps = 90/388 (23%)

Query: 141 PPLAGGAGGAGGAGGGPGPGQAGWLEGGRTGGAGGRGGEGPGGSTAYVVCGVISFALAVG 200
           P  AG  GG GG GGG G G      GG  GG G  GG GP G       G+        
Sbjct: 62  PKGAGAGGGGGGFGGGGGFG-----GGGGGGGGGSFGGGGPPGLGGLFQAGMPKLRSTAN 116

Query: 201 VGAKVAFSKASRAPRAHRDINVP---------RALVDILRHQAGPGTRPDRARSSSLTPG 251
                  S+    P   R  +           R  V    H++GP   P R R     P 
Sbjct: 117 RDNDSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGP-PEPQRNRMPPPRPD 175

Query: 252 IGG-PDSMPPRTPKNLYNTVKTPNLDWRALPP-------PSP------------------ 285
           +G  PDS+PP  P        +P+   R  PP       PSP                  
Sbjct: 176 VGSKPDSIPPPVPSTPRPIQSSPHN--RGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGG 233

Query: 286 SLHYSTLSCSRSFHNLSHLPPSYEAAVKSELNRYSSLKRLAEKDLDEAYLKRRPLELPRG 345
           S+  S LS S  F N   LPP+   A                  LD+   K  P   P G
Sbjct: 234 SIRQSPLSSSSPFSNRPPLPPTPSRA------------------LDD---KPPPPPPPVG 272

Query: 346 TLPLHALRR------PGTGGGYRMEAWGGPEELGLAPAPNPRRVMSQEHLLGDGGRSRYE 399
             P  ++ R      P       + +   P     AP P P         L        E
Sbjct: 273 NRP--SIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDE 330

Query: 400 FTLPRARLVSQEHLLLSSPEALRQSREHLLSPPRSPALPPDPTARASLAASHSNLLLGPG 459
              PR   + Q +L LSS      S   L SP RS  LPP P+ R            G  
Sbjct: 331 --TPR---LPQRNLSLSS------STPPLPSPGRSGPLPPPPSERPPPPVRDPP---GRS 376

Query: 460 GPPTPLRGLPPPSSLHAHHHHALHGSPQ 487
           GP  P    PPP S +     AL  +PQ
Sbjct: 377 GPLPP----PPPVSRNGSTSRALPATPQ 400


>gi|122937450 shisa homolog 3 [Homo sapiens]
          Length = 238

 Score = 56.2 bits (134), Expect = 7e-08
 Identities = 29/73 (39%), Positives = 33/73 (45%), Gaps = 11/73 (15%)

Query: 62  RTGPAGGAGAAARAPPPAELCHGYYDVMGQYDATFNC----STGSYRFCCGTCHYRFCCE 117
           R GPAG       A    E CHG+ DV G Y   F C     T     CCG+C  R+CC 
Sbjct: 15  RWGPAG-------AQQSGEYCHGWVDVQGNYHEGFQCPEDFDTLDATICCGSCALRYCCA 67

Query: 118 HRHMRLAQASCSN 130
               RL Q  C+N
Sbjct: 68  AADARLEQGGCTN 80


>gi|56090523 shisa homolog 2 [Homo sapiens]
          Length = 295

 Score = 56.2 bits (134), Expect = 7e-08
 Identities = 60/246 (24%), Positives = 89/246 (36%), Gaps = 35/246 (14%)

Query: 72  AARAPPPAELCHGYYDVMGQYDATFNCST----GSYRFCCGTCHYRFCCEHRHMRLAQAS 127
           AA A    E CHG+ D  G +   F C      G    CCG+C  R+CC     RL Q  
Sbjct: 28  AAGARASGEYCHGWLDAQGVWRIGFQCPERFDGGDATICCGSCALRYCCSSAEARLDQGG 87

Query: 128 CSNYDTPRWATTPPPLAGGAGGAGGAGGGPGPGQAGWLEGGRTGGAGGRGGEGPGGSTAY 187
           C N D  + A  P     G     G  G   P    +L  G                 A+
Sbjct: 88  CDN-DRQQGAGEP-----GRADKDGPDGSAVPIYVPFLIVGSV-------------FVAF 128

Query: 188 VVCGVISFALAVGVGAKVAFSKASRAPRAHRDI-NVPRALVDILRHQAGPGTRPDRARSS 246
           ++ G +  A            + SRAP  +R +  +P  ++       G  +R     +S
Sbjct: 129 IILGSLVAACCCRCLRPKQDPQQSRAPGGNRLMETIP--MIPSASTSRGSSSRQSSTAAS 186

Query: 247 SLTPGIGGPDSMPPRTPKNLYNTVKTPNLDWRALPPPSPSLHYSTLSCSRSF----HNLS 302
           S +    G  + P R+  N      T N  +  +P      ++S L+C ++     H   
Sbjct: 187 SSSSANSGARAPPTRSQTNCCLPEGTMNNVYVNMP-----TNFSVLNCQQATQIVPHQGQ 241

Query: 303 HLPPSY 308
           +L P Y
Sbjct: 242 YLHPPY 247


>gi|73427806 v-maf musculoaponeurotic fibrosarcoma oncogene homolog
           isoform b [Homo sapiens]
          Length = 373

 Score = 50.1 bits (118), Expect = 5e-06
 Identities = 51/174 (29%), Positives = 63/174 (36%), Gaps = 46/174 (26%)

Query: 24  ATSAEPAGPLPALLAHLRRLTG-------------ALTGGGGAASPGANGTRTGPAGGAG 70
           A    P   + AL+++  +L G             A  G G  AS G +G   GPA    
Sbjct: 105 ALGFSPEDAVEALISNSHQLQGGFDGYARGAQQLAAAAGAGAGASLGGSGEEMGPAAAVV 164

Query: 71  AAARAPPPAELCHGYYDVMGQYDATFNCSTGSYRFCCGTCHYRFCCEHRHMRLAQASCSN 130
           +A  A   A+   G +                Y       H+     H H   A A    
Sbjct: 165 SAVIAAAAAQSGAGPH----------------YHH-----HHHHAAGHHHHPTAGA---- 199

Query: 131 YDTPRWATTPPPLAGGAGGAGGAGGGPGPGQAGWLEGGRTGGAGGRGGEGPGGS 184
              P  A +    AGGAGGAG  GGGP     G   GG  GG GG G  G GG+
Sbjct: 200 ---PGAAGSAAASAGGAGGAG--GGGPASAGGG---GGGGGGGGGGGAAGAGGA 245


>gi|5453736 v-maf musculoaponeurotic fibrosarcoma oncogene homolog
           isoform a [Homo sapiens]
          Length = 403

 Score = 50.1 bits (118), Expect = 5e-06
 Identities = 51/174 (29%), Positives = 63/174 (36%), Gaps = 46/174 (26%)

Query: 24  ATSAEPAGPLPALLAHLRRLTG-------------ALTGGGGAASPGANGTRTGPAGGAG 70
           A    P   + AL+++  +L G             A  G G  AS G +G   GPA    
Sbjct: 105 ALGFSPEDAVEALISNSHQLQGGFDGYARGAQQLAAAAGAGAGASLGGSGEEMGPAAAVV 164

Query: 71  AAARAPPPAELCHGYYDVMGQYDATFNCSTGSYRFCCGTCHYRFCCEHRHMRLAQASCSN 130
           +A  A   A+   G +                Y       H+     H H   A A    
Sbjct: 165 SAVIAAAAAQSGAGPH----------------YHH-----HHHHAAGHHHHPTAGA---- 199

Query: 131 YDTPRWATTPPPLAGGAGGAGGAGGGPGPGQAGWLEGGRTGGAGGRGGEGPGGS 184
              P  A +    AGGAGGAG  GGGP     G   GG  GG GG G  G GG+
Sbjct: 200 ---PGAAGSAAASAGGAGGAG--GGGPASAGGG---GGGGGGGGGGGAAGAGGA 245


>gi|15011916 nucleolar protein family A, member 1 [Homo sapiens]
          Length = 217

 Score = 50.1 bits (118), Expect = 5e-06
 Identities = 26/45 (57%), Positives = 27/45 (60%), Gaps = 3/45 (6%)

Query: 141 PPLAGGAGGAGGA--GGGPGPGQAGWLEGGRTGGAGG-RGGEGPG 182
           PP  GG GG GG   GGG G G+ G   GGR GG GG RGG G G
Sbjct: 167 PPRGGGRGGRGGGRGGGGRGGGRGGGFRGGRGGGGGGFRGGRGGG 211



 Score = 34.7 bits (78), Expect = 0.23
 Identities = 18/39 (46%), Positives = 19/39 (48%)

Query: 145 GGAGGAGGAGGGPGPGQAGWLEGGRTGGAGGRGGEGPGG 183
           GG GG    GGG G  + G     R GG GG GG   GG
Sbjct: 6   GGRGGFNRGGGGGGFNRGGSSNHFRGGGGGGGGGNFRGG 44



 Score = 32.3 bits (72), Expect = 1.1
 Identities = 15/36 (41%), Positives = 18/36 (50%)

Query: 146 GAGGAGGAGGGPGPGQAGWLEGGRTGGAGGRGGEGP 181
           G GG GG G   G G+ G+  GG  GG      +GP
Sbjct: 31  GGGGGGGGGNFRGGGRGGFGRGGGRGGFNKGQDQGP 66



 Score = 30.8 bits (68), Expect = 3.3
 Identities = 18/42 (42%), Positives = 18/42 (42%), Gaps = 6/42 (14%)

Query: 145 GGAGGAGGAG------GGPGPGQAGWLEGGRTGGAGGRGGEG 180
           GG GG    G      GG G G  G   GG  GG G  GG G
Sbjct: 15  GGGGGFNRGGSSNHFRGGGGGGGGGNFRGGGRGGFGRGGGRG 56



 Score = 29.6 bits (65), Expect = 7.3
 Identities = 15/26 (57%), Positives = 16/26 (61%), Gaps = 1/26 (3%)

Query: 159 PGQAGWLEGGRTGG-AGGRGGEGPGG 183
           PG+ G   GG  GG  GGRGG G GG
Sbjct: 162 PGEKGPPRGGGRGGRGGGRGGGGRGG 187


>gi|9506713 nucleolar protein family A, member 1 [Homo sapiens]
          Length = 217

 Score = 50.1 bits (118), Expect = 5e-06
 Identities = 26/45 (57%), Positives = 27/45 (60%), Gaps = 3/45 (6%)

Query: 141 PPLAGGAGGAGGA--GGGPGPGQAGWLEGGRTGGAGG-RGGEGPG 182
           PP  GG GG GG   GGG G G+ G   GGR GG GG RGG G G
Sbjct: 167 PPRGGGRGGRGGGRGGGGRGGGRGGGFRGGRGGGGGGFRGGRGGG 211



 Score = 34.7 bits (78), Expect = 0.23
 Identities = 18/39 (46%), Positives = 19/39 (48%)

Query: 145 GGAGGAGGAGGGPGPGQAGWLEGGRTGGAGGRGGEGPGG 183
           GG GG    GGG G  + G     R GG GG GG   GG
Sbjct: 6   GGRGGFNRGGGGGGFNRGGSSNHFRGGGGGGGGGNFRGG 44



 Score = 32.3 bits (72), Expect = 1.1
 Identities = 15/36 (41%), Positives = 18/36 (50%)

Query: 146 GAGGAGGAGGGPGPGQAGWLEGGRTGGAGGRGGEGP 181
           G GG GG G   G G+ G+  GG  GG      +GP
Sbjct: 31  GGGGGGGGGNFRGGGRGGFGRGGGRGGFNKGQDQGP 66



 Score = 30.8 bits (68), Expect = 3.3
 Identities = 18/42 (42%), Positives = 18/42 (42%), Gaps = 6/42 (14%)

Query: 145 GGAGGAGGAG------GGPGPGQAGWLEGGRTGGAGGRGGEG 180
           GG GG    G      GG G G  G   GG  GG G  GG G
Sbjct: 15  GGGGGFNRGGSSNHFRGGGGGGGGGNFRGGGRGGFGRGGGRG 56



 Score = 29.6 bits (65), Expect = 7.3
 Identities = 15/26 (57%), Positives = 16/26 (61%), Gaps = 1/26 (3%)

Query: 159 PGQAGWLEGGRTGG-AGGRGGEGPGG 183
           PG+ G   GG  GG  GGRGG G GG
Sbjct: 162 PGEKGPPRGGGRGGRGGGRGGGGRGG 187


>gi|4502565 calpain, small subunit 1 [Homo sapiens]
          Length = 268

 Score = 49.3 bits (116), Expect = 9e-06
 Identities = 30/77 (38%), Positives = 37/77 (48%), Gaps = 7/77 (9%)

Query: 145 GGAGGAGGAGGGPGPGQAGWLE----GGRTGGAGGRGGEGPGGSTAYVVCGVISFALAVG 200
           GG GG GG GGG G    G +     GG  GG GG GG G GG TA  + G +  A++  
Sbjct: 13  GGGGGGGGLGGGLGNVLGGLISGAGGGGGGGGGGGGGGGGGGGGTAMRILGGVISAIS-- 70

Query: 201 VGAKVAFSKASRAPRAH 217
             A   ++     PR H
Sbjct: 71  -EAAAQYNPEPPPPRTH 86


>gi|51599151 calpain, small subunit 1 [Homo sapiens]
          Length = 268

 Score = 49.3 bits (116), Expect = 9e-06
 Identities = 30/77 (38%), Positives = 37/77 (48%), Gaps = 7/77 (9%)

Query: 145 GGAGGAGGAGGGPGPGQAGWLE----GGRTGGAGGRGGEGPGGSTAYVVCGVISFALAVG 200
           GG GG GG GGG G    G +     GG  GG GG GG G GG TA  + G +  A++  
Sbjct: 13  GGGGGGGGLGGGLGNVLGGLISGAGGGGGGGGGGGGGGGGGGGGTAMRILGGVISAIS-- 70

Query: 201 VGAKVAFSKASRAPRAH 217
             A   ++     PR H
Sbjct: 71  -EAAAQYNPEPPPPRTH 86


>gi|53829370 neuralized homolog 4 isoform 1 [Homo sapiens]
          Length = 1562

 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 24/44 (54%), Positives = 29/44 (65%), Gaps = 5/44 (11%)

Query: 143 LAGGAGGAGGAGGGPGPGQAGWLEGGRTG---GAGGRGGEGPGG 183
           +A G+GG+GG+GGGPGPG  G   GG +G   G G  GG G GG
Sbjct: 1   MAAGSGGSGGSGGGPGPGPGG--GGGPSGSGSGPGSNGGLGSGG 42



 Score = 30.0 bits (66), Expect = 5.6
 Identities = 18/50 (36%), Positives = 21/50 (42%), Gaps = 6/50 (12%)

Query: 142 PLAGGAGGAGGAGGGPGPGQAGWLEGGRTGGAGGRGGEGPGGSTAYVVCG 191
           P  G  GG G +G G GPG  G L      G+GG      G   +   CG
Sbjct: 15  PGPGPGGGGGPSGSGSGPGSNGGL------GSGGELHPRTGRLVSLSACG 58



 Score = 29.6 bits (65), Expect = 7.3
 Identities = 16/37 (43%), Positives = 17/37 (45%), Gaps = 1/37 (2%)

Query: 140 PPPLAGGAGGAGGAGGGPGPGQAGWLEGGRTGGAGGR 176
           P P  GG GG  G+G GPG    G   GG      GR
Sbjct: 15  PGPGPGGGGGPSGSGSGPG-SNGGLGSGGELHPRTGR 50


>gi|53829368 neuralized homolog 4 isoform 2 [Homo sapiens]
          Length = 1560

 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 24/44 (54%), Positives = 29/44 (65%), Gaps = 5/44 (11%)

Query: 143 LAGGAGGAGGAGGGPGPGQAGWLEGGRTG---GAGGRGGEGPGG 183
           +A G+GG+GG+GGGPGPG  G   GG +G   G G  GG G GG
Sbjct: 1   MAAGSGGSGGSGGGPGPGPGG--GGGPSGSGSGPGSNGGLGSGG 42



 Score = 30.0 bits (66), Expect = 5.6
 Identities = 18/50 (36%), Positives = 21/50 (42%), Gaps = 6/50 (12%)

Query: 142 PLAGGAGGAGGAGGGPGPGQAGWLEGGRTGGAGGRGGEGPGGSTAYVVCG 191
           P  G  GG G +G G GPG  G L      G+GG      G   +   CG
Sbjct: 15  PGPGPGGGGGPSGSGSGPGSNGGL------GSGGELHPRTGRLVSLSACG 58



 Score = 29.6 bits (65), Expect = 7.3
 Identities = 16/37 (43%), Positives = 17/37 (45%), Gaps = 1/37 (2%)

Query: 140 PPPLAGGAGGAGGAGGGPGPGQAGWLEGGRTGGAGGR 176
           P P  GG GG  G+G GPG    G   GG      GR
Sbjct: 15  PGPGPGGGGGPSGSGSGPG-SNGGLGSGGELHPRTGR 50


>gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2
           [Homo sapiens]
          Length = 2191

 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 52/190 (27%), Positives = 65/190 (34%), Gaps = 33/190 (17%)

Query: 49  GGGGAASPGANGTRTGPAGGAGAAARAPPPAELCHGYYDVMGQYDATFNCSTGSYRFCCG 108
           GGG AA P  N      A  +G       P    HG     GQ          +     G
Sbjct: 163 GGGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQHG-----GQQSPGMGMMHSASAAAAG 217

Query: 109 TCHYRFCCEHRHMRLAQASCSNYDTPRWATTPPPLAGGAGGAGGAGGGPGPGQAGWLEGG 168
                   ++ H     + C++Y       + P   GG GG GG GGG G G  G   G 
Sbjct: 218 APGSMDPLQNSHEGYPNSQCNHYP----GYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGA 273

Query: 169 RTGGAG--------------GRGGEGPGGSTAYVVCGVIS--------FALAVGVGAKVA 206
              GAG              G GG G GGS+A    GV+S          +  G G   +
Sbjct: 274 GGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGY--GVLSSPRQQGGGMMMGPGGGGAAS 331

Query: 207 FSKASRAPRA 216
            SKA+    A
Sbjct: 332 LSKAAAGSAA 341



 Score = 29.6 bits (65), Expect = 7.3
 Identities = 19/61 (31%), Positives = 29/61 (47%), Gaps = 1/61 (1%)

Query: 417  SPEALRQSREHLLSPPRSPALPPDPTARASLAASHSNLLLGPGGPPTPLRGLP-PPSSLH 475
            SP + ++S E+ +SP +SP LP     +       S +   P  PP   R +  PP S+ 
Sbjct: 1497 SPASFQRSLENRMSPSKSPFLPSMKMQKVMPTVPTSQVTGPPPQPPPIRREITFPPGSVE 1556

Query: 476  A 476
            A
Sbjct: 1557 A 1557


>gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1
           [Homo sapiens]
          Length = 2231

 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 52/190 (27%), Positives = 65/190 (34%), Gaps = 33/190 (17%)

Query: 49  GGGGAASPGANGTRTGPAGGAGAAARAPPPAELCHGYYDVMGQYDATFNCSTGSYRFCCG 108
           GGG AA P  N      A  +G       P    HG     GQ          +     G
Sbjct: 163 GGGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQHG-----GQQSPGMGMMHSASAAAAG 217

Query: 109 TCHYRFCCEHRHMRLAQASCSNYDTPRWATTPPPLAGGAGGAGGAGGGPGPGQAGWLEGG 168
                   ++ H     + C++Y       + P   GG GG GG GGG G G  G   G 
Sbjct: 218 APGSMDPLQNSHEGYPNSQCNHYP----GYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGA 273

Query: 169 RTGGAG--------------GRGGEGPGGSTAYVVCGVIS--------FALAVGVGAKVA 206
              GAG              G GG G GGS+A    GV+S          +  G G   +
Sbjct: 274 GGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGY--GVLSSPRQQGGGMMMGPGGGGAAS 331

Query: 207 FSKASRAPRA 216
            SKA+    A
Sbjct: 332 LSKAAAGSAA 341



 Score = 29.6 bits (65), Expect = 7.3
 Identities = 19/61 (31%), Positives = 29/61 (47%), Gaps = 1/61 (1%)

Query: 417  SPEALRQSREHLLSPPRSPALPPDPTARASLAASHSNLLLGPGGPPTPLRGLP-PPSSLH 475
            SP + ++S E+ +SP +SP LP     +       S +   P  PP   R +  PP S+ 
Sbjct: 1537 SPASFQRSLENRMSPSKSPFLPSMKMQKVMPTVPTSQVTGPPPQPPPIRREITFPPGSVE 1596

Query: 476  A 476
            A
Sbjct: 1597 A 1597


>gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3
           [Homo sapiens]
          Length = 2178

 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 52/190 (27%), Positives = 65/190 (34%), Gaps = 33/190 (17%)

Query: 49  GGGGAASPGANGTRTGPAGGAGAAARAPPPAELCHGYYDVMGQYDATFNCSTGSYRFCCG 108
           GGG AA P  N      A  +G       P    HG     GQ          +     G
Sbjct: 163 GGGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQHG-----GQQSPGMGMMHSASAAAAG 217

Query: 109 TCHYRFCCEHRHMRLAQASCSNYDTPRWATTPPPLAGGAGGAGGAGGGPGPGQAGWLEGG 168
                   ++ H     + C++Y       + P   GG GG GG GGG G G  G   G 
Sbjct: 218 APGSMDPLQNSHEGYPNSQCNHYP----GYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGA 273

Query: 169 RTGGAG--------------GRGGEGPGGSTAYVVCGVIS--------FALAVGVGAKVA 206
              GAG              G GG G GGS+A    GV+S          +  G G   +
Sbjct: 274 GGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGY--GVLSSPRQQGGGMMMGPGGGGAAS 331

Query: 207 FSKASRAPRA 216
            SKA+    A
Sbjct: 332 LSKAAAGSAA 341



 Score = 29.6 bits (65), Expect = 7.3
 Identities = 19/61 (31%), Positives = 29/61 (47%), Gaps = 1/61 (1%)

Query: 417  SPEALRQSREHLLSPPRSPALPPDPTARASLAASHSNLLLGPGGPPTPLRGLP-PPSSLH 475
            SP + ++S E+ +SP +SP LP     +       S +   P  PP   R +  PP S+ 
Sbjct: 1484 SPASFQRSLENRMSPSKSPFLPSMKMQKVMPTVPTSQVTGPPPQPPPIRREITFPPGSVE 1543

Query: 476  A 476
            A
Sbjct: 1544 A 1544


>gi|109452587 family with sequence similarity 98, member B isoform 1
           [Homo sapiens]
          Length = 433

 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 22/39 (56%), Positives = 23/39 (58%)

Query: 145 GGAGGAGGAGGGPGPGQAGWLEGGRTGGAGGRGGEGPGG 183
           GG GG G  GGG G G+ GW  GG   G GG GG G GG
Sbjct: 340 GGGGGGGRGGGGGGGGRGGWGGGGGGWGGGGGGGGGWGG 378



 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 22/43 (51%), Positives = 24/43 (55%)

Query: 145 GGAGGAGGAGGGPGPGQAGWLEGGRTGGAGGRGGEGPGGSTAY 187
           GG GG GG GGG G G+ G+   G  GG GG GG G  G   Y
Sbjct: 368 GGGGGGGGWGGGGGGGRGGFQGRGDYGGRGGYGGRGGYGGRGY 410



 Score = 46.2 bits (108), Expect = 8e-05
 Identities = 23/39 (58%), Positives = 23/39 (58%)

Query: 145 GGAGGAGGAGGGPGPGQAGWLEGGRTGGAGGRGGEGPGG 183
           GG GG GG GGG G G  G   GG  GG GG GG G GG
Sbjct: 342 GGGGGRGGGGGGGGRGGWGGGGGGWGGGGGGGGGWGGGG 380



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 22/38 (57%), Positives = 22/38 (57%), Gaps = 2/38 (5%)

Query: 146 GAGGAGGAGGGPGPGQAGWLEGGRTGGAGGRGGEGPGG 183
           G GG GG  GG G G  GW  GG  GG GG GG G GG
Sbjct: 348 GGGGGGGGRGGWGGGGGGW--GGGGGGGGGWGGGGGGG 383



 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 23/39 (58%), Positives = 23/39 (58%), Gaps = 1/39 (2%)

Query: 145 GGAGGAGGAGGGPGPGQAGWLEGGRTGGAGGRGGEGPGG 183
           GG GG GG GGG G G  G   GGR G  GG GG G GG
Sbjct: 333 GGRGGWGGGGGGGGRGGGGG-GGGRGGWGGGGGGWGGGG 370



 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 21/38 (55%), Positives = 21/38 (55%)

Query: 146 GAGGAGGAGGGPGPGQAGWLEGGRTGGAGGRGGEGPGG 183
           G  G GG GGG G G  G   GG  GG GG GG G GG
Sbjct: 336 GGWGGGGGGGGRGGGGGGGGRGGWGGGGGGWGGGGGGG 373



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 23/38 (60%), Positives = 23/38 (60%), Gaps = 5/38 (13%)

Query: 146 GAGGAGGAGGGPGPGQAGWLEGGRTGGAGGRGGEGPGG 183
           G GG GG GGG G G  G   GG  GG GGRGG G GG
Sbjct: 331 GGGGRGGWGGGGGGGGRG---GG--GGGGGRGGWGGGG 363



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 21/34 (61%), Positives = 21/34 (61%), Gaps = 4/34 (11%)

Query: 145 GGAGGAGGAGGGPGPGQAGWLEGGRTGGAGGRGG 178
           GG GG GG  GG G G  GW  GG  GG GGRGG
Sbjct: 357 GGWGGGGGGWGGGGGGGGGW--GG--GGGGGRGG 386



 Score = 40.0 bits (92), Expect = 0.005
 Identities = 22/39 (56%), Positives = 22/39 (56%), Gaps = 6/39 (15%)

Query: 145 GGAGGAGGAGGGPGPGQAGWLEGGRTGGAGGRGGEGPGG 183
           GG GG GG GGG G G      GG  GG GG GG G GG
Sbjct: 354 GGRGGWGGGGGGWGGG------GGGGGGWGGGGGGGRGG 386



 Score = 37.7 bits (86), Expect = 0.027
 Identities = 20/43 (46%), Positives = 22/43 (51%)

Query: 145 GGAGGAGGAGGGPGPGQAGWLEGGRTGGAGGRGGEGPGGSTAY 187
           G  GG GG GG  G G  G+ +    GG GG GG G GG   Y
Sbjct: 391 GDYGGRGGYGGRGGYGGRGYGDPYGGGGGGGGGGGGGGGYRRY 433



 Score = 35.0 bits (79), Expect = 0.17
 Identities = 20/43 (46%), Positives = 20/43 (46%), Gaps = 1/43 (2%)

Query: 146 GAGGAGGAGGGPGPGQAGWLEGGRTGGAGGRGGEGP-GGSTAY 187
           G  G GG G G G G  G   GG  GG GG  G G  GG   Y
Sbjct: 357 GGWGGGGGGWGGGGGGGGGWGGGGGGGRGGFQGRGDYGGRGGY 399



 Score = 29.3 bits (64), Expect = 9.5
 Identities = 11/17 (64%), Positives = 11/17 (64%)

Query: 142 PLAGGAGGAGGAGGGPG 158
           P  GG GG GG GGG G
Sbjct: 413 PYGGGGGGGGGGGGGGG 429


>gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sapiens]
          Length = 2161

 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 78/277 (28%), Positives = 99/277 (35%), Gaps = 55/277 (19%)

Query: 245  SSSLTPGIGGPDSMPPRTPKNLYNTVKTPNLDWRALP--------PPSPSLHYSTLSCSR 296
            S+S +PG GG  S+    PK  + T  + +   RA P        PP P L     S   
Sbjct: 834  SASESPGPGGLASLGKHRPKGFFATESSFDPHHRAQPSYERPSFLPPGPGLMLRQKSIGA 893

Query: 297  SFHNLSHLPPSYEAAVKSELNRYSSLKRLAEKDLDEAYLKRRPLELPRGTLPLHALR--- 353
            +  +  +L P    A+K       SL     +D+        P E P  T P+ +     
Sbjct: 894  AEDDRPYLAPP---AMKFS----RSLSVPGSEDIPPPPTTSPP-EPPYSTPPVPSSSGRL 945

Query: 354  RPGTGGGYRMEAWGGPEELGL-----APAPNPRRVMSQEHLLGDGGRSRYEFTLPRARLV 408
             P   GG      GGP           P+P   RV S+E  L   G       LP A   
Sbjct: 946  TPSPRGGPFNPGSGGPLPASSPASFDGPSPPDTRVGSREKSLYHSG------PLPPAHHH 999

Query: 409  SQEHLLLSSPEALRQSREHLLSPPRSPAL-----PPDPTARASLAASHSNLLLGPGGPPT 463
               H    +P    Q   H   PP  P +     P DP  R +L    S L    GG P+
Sbjct: 1000 PPHHHHHHAPPP--QPHHHHAHPPHPPEMETGGSPDDPPPRLALGPQPS-LRGWRGGGPS 1056

Query: 464  PLRGLPPPSSLHAHHHHALHGSPQPAWMSDAGGGGGT 500
            P  G P PS          HGS        AGGGGG+
Sbjct: 1057 PTPGAPSPSH---------HGS--------AGGGGGS 1076



 Score = 35.0 bits (79), Expect = 0.17
 Identities = 127/532 (23%), Positives = 164/532 (30%), Gaps = 135/532 (25%)

Query: 1    MPALLLLVLLASSAGQARARPSNATSAEP-AGPLPALLAHLRRLTGALTGGGGAASPGAN 59
            +P   +++   S++   R+   ++T AEP   P P         TG   GGG + SP   
Sbjct: 1153 IPIPTIIIKAPSTSSSGRSSQGSSTEAEPPTQPEP---------TGGGGGGGSSPSPAPA 1203

Query: 60   GTRTGPAGGAGAAARAPP-PAELCHGYYDVMGQYDATFNCSTGSYRFCCGTCHYRFCCEH 118
             +   P+        +P  PA L     D   Q+ A      G+ R   G          
Sbjct: 1204 MSPVPPSPSPVPTPASPSGPATL-----DFTSQFGAAL---VGAARREGGW--------- 1246

Query: 119  RHMRLAQASCSNYDTPRWATTPPPLAGGAGGAGGAGGGPGP-------------GQAGWL 165
                  Q       T   +T      GG GG G  G  PGP                 +L
Sbjct: 1247 ------QNEARRRSTLFLSTDAGDEDGGDGGLG-TGAAPGPRLRHSKSIDEGMFSAEPYL 1299

Query: 166  EGGRTGGAGGRGGEGPGGSTAYVVCGVISFALAVGVGAKVAFSKASRAPRAHRDINVPRA 225
                 G   G GG G  GS AY            G G   AF+  S  P        PR 
Sbjct: 1300 RLESAGSGAGYGGYG-AGSRAYG-----------GGGGSSAFT--SFLP--------PRP 1337

Query: 226  LVDILRHQAGPGTRP------DRARSSSLTPGIGGPDSMPPRTPKNLYNTVKTPNLDWRA 279
            LV  L  +A     P       R R+   +   GG    PPR P   Y            
Sbjct: 1338 LVHPLTGKALDPASPLGLALAARERALKESSEGGGAPQPPPRPPSPRYEA---------- 1387

Query: 280  LPPPSPSLHYSTLSCSRSFHNLSHLPPS-------YEAAVKSELNRYSSLKRLAEKDLDE 332
             PPP+P  H                PP        Y A + S+     +    A + L  
Sbjct: 1388 -PPPTPHHHSPHAHHEPVLRLWGASPPDPARRELGYRAGLGSQEKSLPASPPAARRSLLH 1446

Query: 333  AYLKRRP----LELPRGTLPLHALRRPGTGGGYRMEAWGGPEELGL----APAPNPRRVM 384
                  P    L L  GT P      PG    +R  A   PE L L         PR  +
Sbjct: 1447 RLPPTAPGVGPLLLQLGTEP--PAPHPGVSKPWRSAAPEEPERLPLHVRFLENCQPRAPV 1504

Query: 385  SQEHLLGDGGRSRYEFTLPRARLVSQEHLLLSSPEALRQSREH----LLSPPRSPA---- 436
            +        GR       P     S    +  SP + R S E+    L+ PP +P+    
Sbjct: 1505 TS-------GRGPPSEDGPGVPPPSPRRSVPPSPTSPRASEENGLPLLVLPPPAPSVDVE 1557

Query: 437  ---------LPPDPTARASLAASHSNLLLGPG-------GPPTPLRGLPPPS 472
                     LPP      S     S L  GP         P TPL  +PPP+
Sbjct: 1558 DGEFLFVEPLPPPLEFSNSFEKPESPLTPGPPHPLPDTPAPATPLPPVPPPA 1609



 Score = 32.3 bits (72), Expect = 1.1
 Identities = 112/456 (24%), Positives = 147/456 (32%), Gaps = 122/456 (26%)

Query: 140  PPPLAGGAGGA--GGAGGGPGPGQAGWLEGGRTGGAGGRGGEGPGGSTAYVVCGVISFAL 197
            PP LA G   +  G  GGGP P   G       G AGG GG   G +  Y       F L
Sbjct: 1036 PPRLALGPQPSLRGWRGGGPSP-TPGAPSPSHHGSAGGGGGSSQGPALRY-------FQL 1087

Query: 198  AVGVGAKVAFSKASRAPRAHRDINVPRALVDILRHQAG---PGTRPDRARSSSLTPGIGG 254
                 A  A    +R+ R  +   V +  V+    + G   P   P    S    P +  
Sbjct: 1088 PPRA-ASAAMYVPARSGRGRKGPLVKQTKVEGEPQKGGGLPPAPSPTSPASPQPPPAVAA 1146

Query: 255  P---DSMPPRT-----PKNLYNTVKTPNLDWRALPP--PSPSLHYSTLSCSRS-FHNLSH 303
            P   +S+P  T     P    +   +      A PP  P P+        S S    +S 
Sbjct: 1147 PSEKNSIPIPTIIIKAPSTSSSGRSSQGSSTEAEPPTQPEPTGGGGGGGSSPSPAPAMSP 1206

Query: 304  LPPSYEAAVKSELNRYSSLKRLAEKDLDEAYLKRRPLELPRGTLPLHALRRPGTGGGYRM 363
            +PPS      S +   +S    A  D    +          G   + A RR G   G++ 
Sbjct: 1207 VPPS-----PSPVPTPASPSGPATLDFTSQF----------GAALVGAARREG---GWQN 1248

Query: 364  EAW---------------GGPEELGLAPAPNPRR---------VMSQEHLL--------- 390
            EA                GG   LG   AP PR          + S E  L         
Sbjct: 1249 EARRRSTLFLSTDAGDEDGGDGGLGTGAAPGPRLRHSKSIDEGMFSAEPYLRLESAGSGA 1308

Query: 391  -------------GDGGRSRYEFTLPRARLV---SQEHLLLSSPEALR-QSREHLLSPPR 433
                         G GG S +   LP   LV   + + L  +SP  L   +RE  L    
Sbjct: 1309 GYGGYGAGSRAYGGGGGSSAFTSFLPPRPLVHPLTGKALDPASPLGLALAARERALKESS 1368

Query: 434  SPALPPDPTARASLAASHSNLLLGPGGPPTPLRGLPPPS----SLHAHHHHALH----GS 485
                 P P  R                PP+P    PPP+    S HAHH   L       
Sbjct: 1369 EGGGAPQPPPR----------------PPSPRYEAPPPTPHHHSPHAHHEPVLRLWGASP 1412

Query: 486  PQPA-----WMSDAGGGGGTLARRPPFQRQGTLEQL 516
            P PA     + +  G    +L   PP  R+  L +L
Sbjct: 1413 PDPARRELGYRAGLGSQEKSLPASPPAARRSLLHRL 1448



 Score = 30.8 bits (68), Expect = 3.3
 Identities = 18/57 (31%), Positives = 26/57 (45%), Gaps = 1/57 (1%)

Query: 21   PSNATSAEPAGPLPALLAHLRRLTGALTGGGGAASPGA-NGTRTGPAGGAGAAARAP 76
            P   T   P  P P L    +       GGG + +PGA + +  G AGG G +++ P
Sbjct: 1024 PEMETGGSPDDPPPRLALGPQPSLRGWRGGGPSPTPGAPSPSHHGSAGGGGGSSQGP 1080


>gi|4885597 sine oculis homeobox homolog 3 [Homo sapiens]
          Length = 332

 Score = 47.4 bits (111), Expect = 3e-05
 Identities = 25/41 (60%), Positives = 25/41 (60%), Gaps = 5/41 (12%)

Query: 146 GAGGAGGAGGGPGPGQAGWLEGGRTGGAGGRGGEGPGGSTA 186
           GAGG GGAGGG G G      G   GGAGG GG G GGS A
Sbjct: 37  GAGGGGGAGGGSGGGN-----GAGGGGAGGAGGGGGGGSRA 72



 Score = 33.5 bits (75), Expect = 0.50
 Identities = 16/37 (43%), Positives = 16/37 (43%)

Query: 45 GALTGGGGAASPGANGTRTGPAGGAGAAARAPPPAEL 81
          G   GGG     GA G   G AGG G      PP EL
Sbjct: 41 GGGAGGGSGGGNGAGGGGAGGAGGGGGGGSRAPPEEL 77



 Score = 31.2 bits (69), Expect = 2.5
 Identities = 19/36 (52%), Positives = 20/36 (55%), Gaps = 7/36 (19%)

Query: 49 GGGGAA---SPGANGTRTGPAGGA----GAAARAPP 77
          GGGG A   S G NG   G AGGA    G  +RAPP
Sbjct: 39 GGGGGAGGGSGGGNGAGGGGAGGAGGGGGGGSRAPP 74


>gi|153792074 proline rich 12 [Homo sapiens]
          Length = 2036

 Score = 47.4 bits (111), Expect = 3e-05
 Identities = 56/176 (31%), Positives = 63/176 (35%), Gaps = 31/176 (17%)

Query: 142 PLAGGAGGAGGAGGGPGP--GQAGWL--EGGRTGGAGGRGGEGPGGSTAYVVCGVISFAL 197
           P A G GGAGG GGG  P     G+   +GG    AGG     P  STA   C  +    
Sbjct: 365 PEAAGGGGAGGGGGGYRPIIQSPGYKTGKGGYGAAAGGATRPPPPRSTATPKCQSLG--- 421

Query: 198 AVGVGAKVAFSKASRAPRAHRDINVPRALVDILRHQA-GPGTRPDRARSSSLTPGIGGPD 256
             G  A  A  KAS A  A      P     +L  QA G G    +A+  S  P   G  
Sbjct: 422 --GPAAAYATGKASGAGGAGGQAYSPGQPQGLLGPQAYGQGFGGGQAQDLSKAPSYSGGP 479

Query: 257 SMPPRTPK-----------------NLYNT----VKTPNLDWRALPPPSPSLHYST 291
             PP  P                   LY         P    + LP  SPSL YST
Sbjct: 480 PQPPSGPPPPGLATCQSYSPDQLQGQLYGVQGEPYPGPAAHSQGLPTASPSLSYST 535



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 131/538 (24%), Positives = 178/538 (33%), Gaps = 113/538 (21%)

Query: 20  RPSNATSAEPAGPLPAL------------LAHLRRLTGALTGGG----GAASP------- 56
           RP++A    P  P  AL            + H   L  +  GGG    GA  P       
Sbjct: 294 RPASAQPPPPPPPAHALQHYLSCGGSYPSMGHRANLACSPLGGGEPSPGAGEPSKAGPSG 353

Query: 57  ---GANGTRTGP----AGGAGAAARAPPPAELCHGYYDVMGQYDATFNCSTGSYRFCCGT 109
              GA+G  TGP     GGAG       P     GY    G Y A    +T         
Sbjct: 354 ATAGASGRATGPEAAGGGGAGGGGGGYRPIIQSPGYKTGKGGYGAAAGGATR-------- 405

Query: 110 CHYRFCCEHRHMRLAQASCSNYDTPRWATTPPPLAGGAGGAGGAGG-GPGPGQAGWLEGG 168
                         A   C +   P  A       G A GAGGAGG    PGQ   L G 
Sbjct: 406 -------PPPPRSTATPKCQSLGGPAAAYA----TGKASGAGGAGGQAYSPGQPQGLLGP 454

Query: 169 RTGGAGGRGGEGPGGSTAYVVCG----VISFALAVGVGAKVAFSKASRAPRAHRDINVPR 224
           +  G G  GG+    S A    G      S     G+    ++S      + +     P 
Sbjct: 455 QAYGQGFGGGQAQDLSKAPSYSGGPPQPPSGPPPPGLATCQSYSPDQLQGQLYGVQGEPY 514

Query: 225 ALVDILRHQAGPGTRPDRARSSSLTPGIG------GPDSM---PPRTPKNLYNTVKTPNL 275
                   Q  P   P  + S+  +P +       GP S+      +P ++   +++P  
Sbjct: 515 P-GPAAHSQGLPTASPSLSYSTGHSPALSGHGGGWGPSSLGGGGEASPSHIIRPLQSPPA 573

Query: 276 DWR---ALPPPSPSLHYSTLSCSRSFHNLSHLPP---SYEAAVKSELNRYSSLKRL---- 325
             R      P +P  + S++  S  F      PP   SY A       +    + L    
Sbjct: 574 TGRPPGVGSPGAPGKYLSSVLASAPF----LAPPGAGSYAAGAGGYKGKGDGSELLAGPG 629

Query: 326 ---AEKDLDEAYLKRRPLELPRGTLPLHALRRPG-TGGGYRMEAWGGPEELGLAPA---- 377
              AE+  DE +L +  L+ P       A    G  G     +  GG    G  P     
Sbjct: 630 GPPAERTEDEEFLIQHLLQAPSPPRTSGADGLVGEDGAADASKGLGGSGGAGGPPGTPYE 689

Query: 378 ---PNPRR-----VMSQEHLLGDGGRSRYEFTLPRARLVSQ-EHLLLSSPEALRQSREHL 428
               +P+R     V+     L +G  +  E  L R +   +       +PE L  S  H 
Sbjct: 690 LAKEDPQRYHLQSVIRTSASLDEGATAALELGLGRLKEKKKGPERGGETPEGLATSVVHY 749

Query: 429 ------------LSPPRSPALPPDPTARASLAASHSNLLLGPGGPPTPLRGLPPPSSL 474
                        SPP     PP PTA+++    H  LLL  GGP  PL   PPP  L
Sbjct: 750 GAGAKELGAFLQKSPP-----PPPPTAQSTQPTPH-GLLLEAGGPDLPLVLPPPPPQL 801



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 77/349 (22%), Positives = 111/349 (31%), Gaps = 34/349 (9%)

Query: 141  PPLAGGAGGAGGAGGGPGPGQAGWLEGGRTGGAGG----------------RGGEGPGGS 184
            P  AG A  +    G   P   G   G +   AGG                + GEG G S
Sbjct: 1182 PTTAGPASASTPTDGAKKPRGRGRGRGRKAEEAGGTRLEPLKPLKIKLSVPKAGEGLGTS 1241

Query: 185  TAYVVCGVISFALAVGVGAKVAFSKASRAPRAHRDIN--VPRALVDILRHQAGPGTRPDR 242
            +   + G    +L   +  +   +K         ++      + +D L+     G R   
Sbjct: 1242 SGDAISGTDHNSLDSSLTREKIEAKIKEVEEKQPEMKSGFMASFLDFLKS----GKRHPP 1297

Query: 243  ARSSSLTPGIGGPDSMPPRTPKNLYNTVKTPNLDWRALPPPSPSLHYSTLSCSRSFHNLS 302
               + LTP +  P S+PP  P       + P       PPPS +        +     L 
Sbjct: 1298 LYQAGLTPPLSPPKSVPPSVPARGLQP-QPPATPAVPHPPPSGAFGLGGALEAAESEGLG 1356

Query: 303  HLPPSYEAAVKSELNRYSSLKRLAEKDLDEAYLKRRPLELPRGTLPLHALRRPGTGGGYR 362
               PS    +  EL R          D +++  K R L+    +  + AL  P   G   
Sbjct: 1357 LGCPSPCKRLDEELKRNLETLPSFSSDEEDSVAKNRDLQESISSA-ISALDDPPLAGPKD 1415

Query: 363  MEAWGGPEELGLAPAPNPRRVMSQEHLLGDGGRSRYEFTLPRARLVSQEHLLLSSPEALR 422
                 GP     A  P P  +        +G         P   L+ ++      P    
Sbjct: 1416 TSTPDGPPLAPAAAVPGPPPLPGLPSANSNG--------TPEPPLLEEKPPPTPPPAPTP 1467

Query: 423  QSREHLLSPPRSPALPPDPTARASLAASHSNLLLGPGGPPTPLRGLPPP 471
            Q +     PP  PALP  P   A   +S     L P  PP P    PPP
Sbjct: 1468 QPQPPPPPPPPQPALPSPPPLVAPTPSSPPPPPLPP--PPPPAMPSPPP 1514


>gi|13994190 frizzled 8 [Homo sapiens]
          Length = 694

 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 26/52 (50%), Positives = 29/52 (55%), Gaps = 7/52 (13%)

Query: 136 WATTPPPLAGGAGGAGGAGGGPGPGQAGWLEGGRTGGAGGRGGEGPGGSTAY 187
           WA+    + GGAG A  AGGG GPG      GG  GG GG GG G GG + Y
Sbjct: 622 WASKGAAVGGGAG-ATAAGGGGGPG------GGGGGGPGGGGGPGGGGGSLY 666



 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 56/214 (26%), Positives = 65/214 (30%), Gaps = 49/214 (22%)

Query: 21  PSNATSAEPAGPLPALLAHLRRLTGALTGGGGAASPGANGTRTGPAGG-----AGAAARA 75
           PS +    P G  P       R  G   GGG AA+P A G   G  GG      G AA  
Sbjct: 177 PSGSGHGRPPGARPP-----HRGGGRGGGGGDAAAPPARG---GGGGGKARPPGGGAAPC 228

Query: 76  PPPAELCHGYYDVMGQYDATFN-CSTGSYRFCCGTCHYRFCCEHRHM------------- 121
            P  +       V  +    +N   TG    C   CH  F  +                 
Sbjct: 229 EPGCQCRAPMVSVSSERHPLYNRVKTGQIANCALPCHNPFFSQDERAFTVFWIGLWSVLC 288

Query: 122 ---RLAQASCSNYDTPRWATTPPP------------------LAGGAGGAGGAGGGPGPG 160
                A  S    D  R+     P                  L  G      +GG PG G
Sbjct: 289 FVSTFATVSTFLIDMERFKYPERPIIFLSACYLFVSVGYLVRLVAGHEKVACSGGAPGAG 348

Query: 161 QAGWLEGGRTG-GAGGRGGEGPGGSTAYVVCGVI 193
            AG   G   G GA G G  GPGG   Y   G +
Sbjct: 349 GAGGAGGAAAGAGAAGAGAGGPGGRGEYEELGAV 382



 Score = 32.7 bits (73), Expect = 0.86
 Identities = 29/85 (34%), Positives = 33/85 (38%), Gaps = 19/85 (22%)

Query: 115 CCEHRHMRLAQASCSNYDTPRWATTPPPLAGGAGGAGGAGGGPGPGQAGWLEGGRTGGAG 174
           C ++    L  A+ S    PR    PPP   G     G+G G  PG      GG  GG G
Sbjct: 148 CMDYNRTDLTTAAPS---PPRRLPPPPP---GEQPPSGSGHGRPPGARPPHRGGGRGGGG 201

Query: 175 G-------RGGEG------PGGSTA 186
           G       RGG G      PGG  A
Sbjct: 202 GDAAAPPARGGGGGGKARPPGGGAA 226



 Score = 29.6 bits (65), Expect = 7.3
 Identities = 19/53 (35%), Positives = 23/53 (43%), Gaps = 3/53 (5%)

Query: 462 PTPLRGLPPPSSLHAHHHHALHGSP---QPAWMSDAGGGGGTLARRPPFQRQG 511
           P+P R LPPP         + HG P   +P       GGGG  A  PP +  G
Sbjct: 161 PSPPRRLPPPPPGEQPPSGSGHGRPPGARPPHRGGGRGGGGGDAAAPPARGGG 213



 Score = 29.3 bits (64), Expect = 9.5
 Identities = 13/27 (48%), Positives = 13/27 (48%)

Query: 145 GGAGGAGGAGGGPGPGQAGWLEGGRTG 171
           GG GG  G GGGPG G         TG
Sbjct: 646 GGGGGGPGGGGGPGGGGGSLYSDVSTG 672


>gi|221219000 phospholipase C-like 2 isoform 1 [Homo sapiens]
          Length = 1127

 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 34/99 (34%), Positives = 44/99 (44%), Gaps = 1/99 (1%)

Query: 145 GGAGGAGGAGGGPGPGQAGWLEGGRTGGAGGRGGEGPGGSTAYVVCGVISFALAVGVGAK 204
           G AGGA     GP  G  G L+ G  G  GG GG    G   Y   GV +   ++GV   
Sbjct: 8   GAAGGALPTSPGPALGAKGALKAG-VGEGGGGGGRLGHGRARYDSGGVSNGDCSLGVSGD 66

Query: 205 VAFSKASRAPRAHRDINVPRALVDILRHQAGPGTRPDRA 243
            A +  +R PR       P A+V  L  ++ PG  P R+
Sbjct: 67  EARASPTRGPRGVALAPTPSAVVCTLPRESKPGGLPRRS 105


>gi|110347449 POU domain, class 4, transcription factor 1 [Homo
           sapiens]
          Length = 419

 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 25/43 (58%), Positives = 25/43 (58%), Gaps = 3/43 (6%)

Query: 144 AGGAGGAGGAGG---GPGPGQAGWLEGGRTGGAGGRGGEGPGG 183
           AGGAG A G GG   GPG G      GG  GG GG GG GPGG
Sbjct: 131 AGGAGAAAGGGGAHDGPGGGGGPGGGGGPGGGPGGGGGGGPGG 173



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 24/43 (55%), Positives = 24/43 (55%), Gaps = 3/43 (6%)

Query: 144 AGGAGGAGGAGGGPGPGQAGWLEGGRTGGAG---GRGGEGPGG 183
           AGG G   G GGG GPG  G   GG  GG G   G GG GPGG
Sbjct: 138 AGGGGAHDGPGGGGGPGGGGGPGGGPGGGGGGGPGGGGGGPGG 180



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 24/40 (60%), Positives = 24/40 (60%), Gaps = 1/40 (2%)

Query: 145 GGAGGAGGAGGGPGPGQAGWLEGGRTGGAGGRGGEGPGGS 184
           GG GG GG GGGPG G  G   GG  GG GG GG   GGS
Sbjct: 148 GGGGGPGG-GGGPGGGPGGGGGGGPGGGGGGPGGGLLGGS 186


>gi|33620755 YEATS domain containing 2 [Homo sapiens]
          Length = 1422

 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 24/51 (47%), Positives = 28/51 (54%), Gaps = 6/51 (11%)

Query: 144 AGGAGGAGGAGGGPGPGQAGWLEGGRTGGAGGRGG------EGPGGSTAYV 188
           A G  GAGG GGG G G +G   GG TGG GG  G       GPGG + ++
Sbjct: 797 ASGGSGAGGGGGGGGGGGSGSGGGGSTGGGGGTAGGGTQSTAGPGGISQHL 847



 Score = 38.1 bits (87), Expect = 0.020
 Identities = 21/48 (43%), Positives = 23/48 (47%)

Query: 147 AGGAGGAGGGPGPGQAGWLEGGRTGGAGGRGGEGPGGSTAYVVCGVIS 194
           A G  GAGGG G G  G    G  G  GG GG   GG+ +    G IS
Sbjct: 797 ASGGSGAGGGGGGGGGGGSGSGGGGSTGGGGGTAGGGTQSTAGPGGIS 844



 Score = 37.7 bits (86), Expect = 0.027
 Identities = 21/50 (42%), Positives = 25/50 (50%), Gaps = 4/50 (8%)

Query: 137 ATTPPPLAGGAGGAGGAGGGPGPGQAGWLEGGRTGGAGGRGGEGPGGSTA 186
           AT    L  G+  +GG+G G G G      GG   G+GG G  G GG TA
Sbjct: 785 ATNNANLQSGSAASGGSGAGGGGGGG----GGGGSGSGGGGSTGGGGGTA 830


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.135    0.429 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,878,580
Number of Sequences: 37866
Number of extensions: 2131481
Number of successful extensions: 29189
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 382
Number of HSP's successfully gapped in prelim test: 697
Number of HSP's that attempted gapping in prelim test: 15645
Number of HSP's gapped (non-prelim): 9230
length of query: 538
length of database: 18,247,518
effective HSP length: 107
effective length of query: 431
effective length of database: 14,195,856
effective search space: 6118413936
effective search space used: 6118413936
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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