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Search of human proteins with 223555975
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|223555975 tropomyosin 4 isoform 1 [Homo sapiens]
(284 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|223555975 tropomyosin 4 isoform 1 [Homo sapiens] 540 e-154
gi|63252896 tropomyosin 1 alpha chain isoform 3 [Homo sapiens] 465 e-131
gi|47519616 tropomyosin 2 (beta) isoform 2 [Homo sapiens] 449 e-126
gi|42476296 tropomyosin 2 (beta) isoform 1 [Homo sapiens] 444 e-125
gi|63252900 tropomyosin 1 alpha chain isoform 4 [Homo sapiens] 443 e-125
gi|114155140 tropomyosin 3 isoform 1 [Homo sapiens] 443 e-125
gi|63252898 tropomyosin 1 alpha chain isoform 1 [Homo sapiens] 442 e-124
gi|63252902 tropomyosin 1 alpha chain isoform 2 [Homo sapiens] 423 e-119
gi|27597085 tropomyosin 1 alpha chain isoform 5 [Homo sapiens] 419 e-117
gi|63252906 tropomyosin 1 alpha chain isoform 7 [Homo sapiens] 401 e-112
gi|4507651 tropomyosin 4 isoform 2 [Homo sapiens] 397 e-111
gi|114155144 tropomyosin 3 isoform 4 [Homo sapiens] 334 6e-92
gi|114155148 tropomyosin 3 isoform 5 [Homo sapiens] 325 4e-89
gi|63252904 tropomyosin 1 alpha chain isoform 6 [Homo sapiens] 321 5e-88
gi|24119203 tropomyosin 3 isoform 2 [Homo sapiens] 315 2e-86
gi|114155146 tropomyosin 3 isoform 3 [Homo sapiens] 306 1e-83
gi|224922812 tropomyosin 2 (beta) isoform 3 [Homo sapiens] 287 6e-78
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 89 6e-18
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 83 3e-16
gi|38044112 restin isoform b [Homo sapiens] 82 7e-16
gi|4506751 restin isoform a [Homo sapiens] 82 7e-16
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 81 9e-16
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 80 2e-15
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 80 2e-15
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 80 2e-15
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 80 2e-15
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 78 1e-14
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 78 1e-14
gi|157738667 FYVE and coiled-coil domain containing 1 [Homo sapi... 78 1e-14
gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens] 77 1e-14
>gi|223555975 tropomyosin 4 isoform 1 [Homo sapiens]
Length = 284
Score = 540 bits (1390), Expect = e-154
Identities = 284/284 (100%), Positives = 284/284 (100%)
Query: 1 MEAIKKKMQMLKLDKENAIDRAEQAEADKKAAEDKCKQVEEELTHLQKKLKGTEDELDKY 60
MEAIKKKMQMLKLDKENAIDRAEQAEADKKAAEDKCKQVEEELTHLQKKLKGTEDELDKY
Sbjct: 1 MEAIKKKMQMLKLDKENAIDRAEQAEADKKAAEDKCKQVEEELTHLQKKLKGTEDELDKY 60
Query: 61 SEDLKDAQEKLELTEKKASDAEGDVAALNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
SEDLKDAQEKLELTEKKASDAEGDVAALNRRIQLVEEELDRAQERLATALQKLEEAEKAA
Sbjct: 61 SEDLKDAQEKLELTEKKASDAEGDVAALNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 121 DESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAE 180
DESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAE
Sbjct: 121 DESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAE 180
Query: 181 ERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAE 240
ERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAE
Sbjct: 181 ERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAE 240
Query: 241 FAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQTLNELNCI 284
FAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQTLNELNCI
Sbjct: 241 FAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQTLNELNCI 284
>gi|63252896 tropomyosin 1 alpha chain isoform 3 [Homo sapiens]
Length = 284
Score = 465 bits (1196), Expect = e-131
Identities = 242/282 (85%), Positives = 265/282 (93%)
Query: 1 MEAIKKKMQMLKLDKENAIDRAEQAEADKKAAEDKCKQVEEELTHLQKKLKGTEDELDKY 60
M+AIKKKMQMLKLDKENA+DRAEQAEADKKAAED+ KQ+E+EL LQKKLKGTEDELDKY
Sbjct: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
Query: 61 SEDLKDAQEKLELTEKKASDAEGDVAALNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
SE LKDAQEKLEL EKKA+DAE DVA+LNRRIQLVEEELDRAQERLATALQKLEEAEKAA
Sbjct: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 121 DESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAE 180
DESERGMKVIE+RA KDEEKMEIQE+QLKEAKHIAE+ADRKYEEVARKLVI+E +LERAE
Sbjct: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
Query: 181 ERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAE 240
ERAE+SE KC +LEEELK VTNNLKSLEA +EKYS+KED+YEEEIK+LSDKLKEAETRAE
Sbjct: 181 ERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
Query: 241 FAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQTLNELN 282
FAER+V KLEK+IDDLEEK+A AKEEN+ +HQ LDQTL ELN
Sbjct: 241 FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELN 282
>gi|47519616 tropomyosin 2 (beta) isoform 2 [Homo sapiens]
Length = 284
Score = 449 bits (1154), Expect = e-126
Identities = 236/282 (83%), Positives = 258/282 (91%)
Query: 1 MEAIKKKMQMLKLDKENAIDRAEQAEADKKAAEDKCKQVEEELTHLQKKLKGTEDELDKY 60
M+AIKKKMQMLKLDKENAIDRAEQAEADKK AED+CKQ+EEE LQKKLKGTEDE++KY
Sbjct: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY 60
Query: 61 SEDLKDAQEKLELTEKKASDAEGDVAALNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
SE +K+AQEKLE EKKA+DAE DVA+LNRRIQLVEEELDRAQERLATALQKLEEAEKAA
Sbjct: 61 SESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 121 DESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAE 180
DESERGMKVIENRAMKDEEKME+QEMQLKEAKHIAE++DRKYEEVARKLVILEGELER+E
Sbjct: 121 DESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSE 180
Query: 181 ERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAE 240
ERAEV+E + LEEEL+ + LKSL A+ E+YS KEDKYEEEIKLL +KLKEAETRAE
Sbjct: 181 ERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAE 240
Query: 241 FAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQTLNELN 282
FAER+VAKLEKTIDDLEE LA AKEENV +HQTLDQTL ELN
Sbjct: 241 FAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLLELN 282
>gi|42476296 tropomyosin 2 (beta) isoform 1 [Homo sapiens]
Length = 284
Score = 444 bits (1142), Expect = e-125
Identities = 231/284 (81%), Positives = 258/284 (90%)
Query: 1 MEAIKKKMQMLKLDKENAIDRAEQAEADKKAAEDKCKQVEEELTHLQKKLKGTEDELDKY 60
M+AIKKKMQMLKLDKENAIDRAEQAEADKK AED+CKQ+EEE LQKKLKGTEDE++KY
Sbjct: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY 60
Query: 61 SEDLKDAQEKLELTEKKASDAEGDVAALNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
SE +K+AQEKLE EKKA+DAE DVA+LNRRIQLVEEELDRAQERLATALQKLEEAEKAA
Sbjct: 61 SESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 121 DESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAE 180
DESERGMKVIENRAMKDEEKME+QEMQLKEAKHIAE++DRKYEEVARKLVILEGELER+E
Sbjct: 121 DESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSE 180
Query: 181 ERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAE 240
ERAEV+E KCGDLEEELK VTNNLKSLEA ++KYS KEDKYEEEIKLL +KLKEAETRAE
Sbjct: 181 ERAEVAESKCGDLEEELKIVTNNLKSLEAQADKYSTKEDKYEEEIKLLEEKLKEAETRAE 240
Query: 241 FAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQTLNELNCI 284
FAER+VAKLEKTIDDLE+++ K + + + LD LN++ +
Sbjct: 241 FAERSVAKLEKTIDDLEDEVYAQKMKYKAISEELDNALNDITSL 284
>gi|63252900 tropomyosin 1 alpha chain isoform 4 [Homo sapiens]
Length = 284
Score = 443 bits (1139), Expect = e-125
Identities = 232/282 (82%), Positives = 259/282 (91%)
Query: 1 MEAIKKKMQMLKLDKENAIDRAEQAEADKKAAEDKCKQVEEELTHLQKKLKGTEDELDKY 60
M+AIKKKMQMLKLDKENA+DRAEQAEADKKAAED+ KQ+E+EL LQKKLKGTEDELDKY
Sbjct: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
Query: 61 SEDLKDAQEKLELTEKKASDAEGDVAALNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
SE LKDAQEKLEL EKKA+DAE DVA+LNRRIQLVEEELDRAQERLATALQKLEEAEKAA
Sbjct: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 121 DESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAE 180
DESERGMKVIE+RA KDEEKMEIQE+QLKEAKHIAE+ADRKYEEVARKLVI+E +LERAE
Sbjct: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
Query: 181 ERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAE 240
ERAE+SE + LEE+L+ + LK+L AA +KYS+KED+YEEEIK+LSDKLKEAETRAE
Sbjct: 181 ERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
Query: 241 FAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQTLNELN 282
FAER+V KLEK+IDDLEEK+A AKEEN+ +HQ LDQTL ELN
Sbjct: 241 FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELN 282
>gi|114155140 tropomyosin 3 isoform 1 [Homo sapiens]
Length = 285
Score = 443 bits (1139), Expect = e-125
Identities = 229/284 (80%), Positives = 260/284 (91%)
Query: 1 MEAIKKKMQMLKLDKENAIDRAEQAEADKKAAEDKCKQVEEELTHLQKKLKGTEDELDKY 60
MEAIKKKMQMLKLDKENA+DRAEQAEA++K AE++ KQ+E+EL +QKKLKGTEDELDKY
Sbjct: 2 MEAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKY 61
Query: 61 SEDLKDAQEKLELTEKKASDAEGDVAALNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
SE LKDAQEKLEL EKKA+DAE +VA+LNRRIQLVEEELDRAQERLATALQKLEEAEKAA
Sbjct: 62 SEALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 121
Query: 121 DESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAE 180
DESERGMKVIENRA+KDEEKME+QE+QLKEAKHIAEEADRKYEEVARKLVI+EG+LER E
Sbjct: 122 DESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTE 181
Query: 181 ERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAE 240
ERAE++E KC +LEEELKNVTNNLKSLEA +EKYS+KEDKYEEEIK+L+DKLKEAETRAE
Sbjct: 182 ERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAE 241
Query: 241 FAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQTLNELNCI 284
FAER+VAKLEKTIDDLE++L K + + + LD LN++ I
Sbjct: 242 FAERSVAKLEKTIDDLEDELYAQKLKYKAISEELDHALNDMTSI 285
>gi|63252898 tropomyosin 1 alpha chain isoform 1 [Homo sapiens]
Length = 284
Score = 442 bits (1136), Expect = e-124
Identities = 231/284 (81%), Positives = 258/284 (90%)
Query: 1 MEAIKKKMQMLKLDKENAIDRAEQAEADKKAAEDKCKQVEEELTHLQKKLKGTEDELDKY 60
M+AIKKKMQMLKLDKENA+DRAEQAEADKKAAED+ KQ+E+EL LQKKLKGTEDELDKY
Sbjct: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
Query: 61 SEDLKDAQEKLELTEKKASDAEGDVAALNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
SE LKDAQEKLEL EKKA+DAE DVA+LNRRIQLVEEELDRAQERLATALQKLEEAEKAA
Sbjct: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 121 DESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAE 180
DESERGMKVIE+RA KDEEKMEIQE+QLKEAKHIAE+ADRKYEEVARKLVI+E +LERAE
Sbjct: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
Query: 181 ERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAE 240
ERAE+SE KC +LEEELK VTNNLKSLEA +EKYS+KED+YEEEIK+LSDKLKEAETRAE
Sbjct: 181 ERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
Query: 241 FAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQTLNELNCI 284
FAER+V KLEK+IDDLE++L K + + + LD LN++ I
Sbjct: 241 FAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSI 284
>gi|63252902 tropomyosin 1 alpha chain isoform 2 [Homo sapiens]
Length = 284
Score = 423 bits (1088), Expect = e-119
Identities = 221/282 (78%), Positives = 253/282 (89%)
Query: 1 MEAIKKKMQMLKLDKENAIDRAEQAEADKKAAEDKCKQVEEELTHLQKKLKGTEDELDKY 60
M+AIKKKMQMLKLDKENA+DRAEQAEADKKAAED+ KQ+EE++ +K L+ +EDE D+
Sbjct: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRV 60
Query: 61 SEDLKDAQEKLELTEKKASDAEGDVAALNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
E+L A++ L E+ A+ AE DVA+LNRRIQLVEEELDRAQERLATALQKLEEAEKAA
Sbjct: 61 LEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 121 DESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAE 180
DESERGMKVIE+RA KDEEKMEIQE+QLKEAKHIAE+ADRKYEEVARKLVI+E +LERAE
Sbjct: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
Query: 181 ERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAE 240
ERAE+SE KC +LEEELK VTNNLKSLEA +EKYS+KED+YEEEIK+LSDKLKEAETRAE
Sbjct: 181 ERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
Query: 241 FAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQTLNELN 282
FAER+V KLEK+IDDLEEK+A AKEEN+ +HQ LDQTL ELN
Sbjct: 241 FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELN 282
>gi|27597085 tropomyosin 1 alpha chain isoform 5 [Homo sapiens]
Length = 284
Score = 419 bits (1076), Expect = e-117
Identities = 220/281 (78%), Positives = 251/281 (89%)
Query: 1 MEAIKKKMQMLKLDKENAIDRAEQAEADKKAAEDKCKQVEEELTHLQKKLKGTEDELDKY 60
M+AIKKKMQMLKLDKENA+DRAEQAEADKKAAED+ KQ+E+EL LQKKLKGTEDELDKY
Sbjct: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
Query: 61 SEDLKDAQEKLELTEKKASDAEGDVAALNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
SE LKDAQEKLEL EKKA+DAE DVA+LNRRIQLVEEELDRAQERLATALQKLEEAEKAA
Sbjct: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 121 DESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAE 180
DESERGMKVIE+RA KDEEKMEIQE+QLKEAKHIAE+ADRKYEEVARKLVI+E +LERAE
Sbjct: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
Query: 181 ERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAE 240
ERAE+SE + LEE+L+ + LK+L AA +KYS+KED+YEEEIK+LSDKLKEAETRAE
Sbjct: 181 ERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
Query: 241 FAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQTLNEL 281
FAER+V KLEK+IDDLE++L K + + + LD LN++
Sbjct: 241 FAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDM 281
>gi|63252906 tropomyosin 1 alpha chain isoform 7 [Homo sapiens]
Length = 284
Score = 401 bits (1031), Expect = e-112
Identities = 211/282 (74%), Positives = 247/282 (87%)
Query: 1 MEAIKKKMQMLKLDKENAIDRAEQAEADKKAAEDKCKQVEEELTHLQKKLKGTEDELDKY 60
M+AIKKKMQMLKLDKENA+DRAEQAEADKKAAED+ KQ+EE++ +K L+ +EDE D+
Sbjct: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRV 60
Query: 61 SEDLKDAQEKLELTEKKASDAEGDVAALNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
E+L A++ L E+ A+ AE DVA+LNRRIQLVEEELDRAQERLATALQKLEEAEKAA
Sbjct: 61 LEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 121 DESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAE 180
DESERGMKVIE+RA KDEEKMEIQE+QLKEAKHIAE+ADRKYEEVARKLVI+E +LERAE
Sbjct: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
Query: 181 ERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAE 240
ERAE+SE + LEE+L+ + LK+L AA +KYS+KED+YEEEIK+LSDKLKEAETRAE
Sbjct: 181 ERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
Query: 241 FAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQTLNELN 282
FAER+V KLEK+IDDLEEK+A AKEEN+ +HQ LDQTL ELN
Sbjct: 241 FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELN 282
>gi|4507651 tropomyosin 4 isoform 2 [Homo sapiens]
Length = 248
Score = 397 bits (1019), Expect = e-111
Identities = 209/242 (86%), Positives = 223/242 (92%)
Query: 43 LTHLQKKLKGTEDELDKYSEDLKDAQEKLELTEKKASDAEGDVAALNRRIQLVEEELDRA 102
L +++K++ + + D+ + + Q +L+ ++ AEGDVAALNRRIQLVEEELDRA
Sbjct: 7 LEAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDRA 66
Query: 103 QERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKY 162
QERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKY
Sbjct: 67 QERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKY 126
Query: 163 EEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYE 222
EEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYE
Sbjct: 127 EEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYE 186
Query: 223 EEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQTLNELN 282
EEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQTLNELN
Sbjct: 187 EEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQTLNELN 246
Query: 283 CI 284
CI
Sbjct: 247 CI 248
Score = 57.8 bits (138), Expect = 1e-08
Identities = 40/121 (33%), Positives = 65/121 (53%), Gaps = 14/121 (11%)
Query: 2 EAIKKKMQMLKLDKENAIDRAEQAEADKKAAEDKCKQVEEELTHLQKKLKGTE------- 54
E + +K+ +L+ + E A +RAE +E KC +EEEL ++ LK E
Sbjct: 127 EEVARKLVILEGELERAEERAEVSEL-------KCGDLEEELKNVTNNLKSLEAASEKYS 179
Query: 55 DELDKYSEDLKDAQEKLELTEKKASDAEGDVAALNRRIQLVEEELDRAQERLATALQKLE 114
++ DKY E++K +KL+ E +A AE VA L + I +EE+L +A+E Q L+
Sbjct: 180 EKEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLD 239
Query: 115 E 115
+
Sbjct: 240 Q 240
>gi|114155144 tropomyosin 3 isoform 4 [Homo sapiens]
Length = 248
Score = 334 bits (856), Expect = 6e-92
Identities = 174/237 (73%), Positives = 205/237 (86%)
Query: 46 LQKKLKGTEDELDKYSEDLKDAQEKLELTEKKASDAEGDVAALNRRIQLVEEELDRAQER 105
+++K++ + + D E + Q ++E + AE +VA+LNRRIQLVEEELDRAQER
Sbjct: 10 VKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQER 69
Query: 106 LATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEV 165
LATALQKLEEAEKAADESERGMKVIENRA+KDEEKME+QE+QLKEAKHIAEEADRKYEEV
Sbjct: 70 LATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEV 129
Query: 166 ARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEI 225
ARKLVI+EG+LER EERAE++E KC +LEEELKNVTNNLKSLEA +EKYS+KEDKYEEEI
Sbjct: 130 ARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEI 189
Query: 226 KLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQTLNELN 282
K+L+DKLKEAETRAEFAER+VAKLEKTIDDLE+KL KEE++ + LDQTL +LN
Sbjct: 190 KILTDKLKEAETRAEFAERSVAKLEKTIDDLEDKLKCTKEEHLCTQRMLDQTLLDLN 246
>gi|114155148 tropomyosin 3 isoform 5 [Homo sapiens]
Length = 247
Score = 325 bits (832), Expect = 4e-89
Identities = 171/236 (72%), Positives = 200/236 (84%)
Query: 46 LQKKLKGTEDELDKYSEDLKDAQEKLELTEKKASDAEGDVAALNRRIQLVEEELDRAQER 105
+++K++ + + D E + Q ++E + AE +VA+LNRRIQLVEEELDRAQER
Sbjct: 10 VKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQER 69
Query: 106 LATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEV 165
LATALQKLEEAEKAADESERGMKVIENRA+KDEEKME+QE+QLKEAKHIAEEADRKYEEV
Sbjct: 70 LATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEV 129
Query: 166 ARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEI 225
ARKLVI+EG+LER EERAE++E KC +LEEELKNVTNNLKSLEA +EKYS+KEDKYEEEI
Sbjct: 130 ARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEI 189
Query: 226 KLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQTLNEL 281
K+L+DKLKEAETRAEFAER+VAKLEKTIDDLEE+L E N L L TL++L
Sbjct: 190 KILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLERNRLLSNELKLTLHDL 245
Score = 28.1 bits (61), Expect = 9.1
Identities = 14/81 (17%), Positives = 40/81 (49%)
Query: 197 LKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDL 256
++ V ++ L+ ++ E+ ++ + E++ ++AE R + +E+ +D
Sbjct: 7 IEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRA 66
Query: 257 EEKLAQAKEENVGLHQTLDQT 277
+E+LA A ++ + D++
Sbjct: 67 QERLATALQKLEEAEKAADES 87
>gi|63252904 tropomyosin 1 alpha chain isoform 6 [Homo sapiens]
Length = 245
Score = 321 bits (822), Expect = 5e-88
Identities = 171/238 (71%), Positives = 198/238 (83%)
Query: 43 LTHLQKKLKGTEDELDKYSEDLKDAQEKLELTEKKASDAEGDVAALNRRIQLVEEELDRA 102
L +++K++ +++ D E Q +L+ K AE DVA+LNRRIQLVEEELDRA
Sbjct: 7 LEAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEELDRA 66
Query: 103 QERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKY 162
QERLATALQKLEEAEKAADESERGMKVIE+RA KDEEKMEIQE+QLKEAKHIAE+ADRKY
Sbjct: 67 QERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKY 126
Query: 163 EEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYE 222
EEVARKLVI+E +LERAEERAE+SE KC +LEEELK VTNNLKSLEA +EKYS+KED+YE
Sbjct: 127 EEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYE 186
Query: 223 EEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQTLNE 280
EEIK+LSDKLKEAETRAEFAER+V KLEK+IDDLE++L Q E+N L L LNE
Sbjct: 187 EEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQLYQQLEQNRRLTNELKLALNE 244
Score = 55.1 bits (131), Expect = 7e-08
Identities = 33/121 (27%), Positives = 64/121 (52%), Gaps = 10/121 (8%)
Query: 2 EAIKKKMQMLKLDKENAIDRAEQAEADKKAAEDKCKQVEEELTHLQKKLKGTEDELDKYS 61
E + +K+ +++ D E A +RAE +E KC ++EEEL + LK E + +KYS
Sbjct: 127 EEVARKLVIIESDLERAEERAELSEG-------KCAELEEELKTVTNNLKSLEAQAEKYS 179
Query: 62 EDLKDAQEKLELTEKKASDAEGDVAALNRRIQLVEEELDRAQERLATALQKLEEAEKAAD 121
+ +E++++ K +AE R + +E+ +D +++L Q+LE+ + +
Sbjct: 180 QKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQL---YQQLEQNRRLTN 236
Query: 122 E 122
E
Sbjct: 237 E 237
Score = 47.0 bits (110), Expect = 2e-05
Identities = 37/173 (21%), Positives = 77/173 (44%), Gaps = 8/173 (4%)
Query: 1 MEAIKKKMQMLKLDKENAIDRAEQAEADKKAAEDKCKQVEEELTHLQKKLKGTEDELDKY 60
++ +++++ + A+ + E+AE +E K +E ++K++ E +L +
Sbjct: 56 IQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEA 115
Query: 61 SEDLKDAQEKLELTEKKASDAEGDVAALNRRIQL-------VEEELDRAQERLATALQKL 113
+DA K E +K E D+ R +L +EEEL L + +
Sbjct: 116 KHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQA 175
Query: 114 EEAEKAADESERGMKVIENRAMKDEEKMEIQEMQL-KEAKHIAEEADRKYEEV 165
E+ + D E +KV+ ++ + E + E E + K K I + D+ Y+++
Sbjct: 176 EKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQLYQQL 228
Score = 42.0 bits (97), Expect = 6e-04
Identities = 39/167 (23%), Positives = 75/167 (44%), Gaps = 37/167 (22%)
Query: 16 ENAIDRAEQAEADKKAAEDKCKQVEEELTHLQKKLKGT----EDELDKYSE--------- 62
E A A+++E K E + ++ EE++ + +LK ED KY E
Sbjct: 78 EEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIE 137
Query: 63 -DLKDAQEKLELTEKKASDAEGDVAALNRRIQLVE--------------EELDRAQERLA 107
DL+ A+E+ EL+E K ++ E ++ + ++ +E EE+ ++L
Sbjct: 138 SDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLK 197
Query: 108 TALQKLEEAEKAADESERGMKVIE---------NRAMKDEEKMEIQE 145
A + E AE++ + E+ + +E NR + +E K+ + E
Sbjct: 198 EAETRAEFAERSVTKLEKSIDDLEDQLYQQLEQNRRLTNELKLALNE 244
>gi|24119203 tropomyosin 3 isoform 2 [Homo sapiens]
Length = 248
Score = 315 bits (808), Expect = 2e-86
Identities = 163/237 (68%), Positives = 200/237 (84%)
Query: 46 LQKKLKGTEDELDKYSEDLKDAQEKLELTEKKASDAEGDVAALNRRIQLVEEELDRAQER 105
+++K++ + + D E + Q ++E + AE +VA+LNRRIQLVEEELDRAQER
Sbjct: 10 VKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQER 69
Query: 106 LATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEV 165
LATALQKLEEAEKAADESERGMKVIENRA+KDEEKME+QE+QLKEAKHIAEEADRKYEEV
Sbjct: 70 LATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEV 129
Query: 166 ARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEI 225
ARKLVI+EG+LER EERAE++E +C +++E+++ + NLK L AA EKYS+KEDKYEEEI
Sbjct: 130 ARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEI 189
Query: 226 KLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQTLNELN 282
K+L+DKLKEAETRAEFAER+VAKLEKTIDDLE+KL KEE++ + LDQTL +LN
Sbjct: 190 KILTDKLKEAETRAEFAERSVAKLEKTIDDLEDKLKCTKEEHLCTQRMLDQTLLDLN 246
Score = 54.7 bits (130), Expect = 9e-08
Identities = 35/161 (21%), Positives = 79/161 (49%)
Query: 124 ERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAEERA 183
+R ++V++ +A EE+ E + +++ + E+A+ + + R++ ++E EL+RA+ER
Sbjct: 11 KRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERL 70
Query: 184 EVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFAE 243
+ K + E+ +K +E + K EK + E ++K +EA+ + E
Sbjct: 71 ATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVA 130
Query: 244 RTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQTLNELNCI 284
R + +E ++ EE+ A+ + + + L C+
Sbjct: 131 RKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCL 171
Score = 50.4 bits (119), Expect = 2e-06
Identities = 30/114 (26%), Positives = 61/114 (53%)
Query: 2 EAIKKKMQMLKLDKENAIDRAEQAEADKKAAEDKCKQVEEELTHLQKKLKGTEDELDKYS 61
E + +K+ +++ D E +RAE AE+ + +++ + +++ L L + + DKY
Sbjct: 127 EEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYE 186
Query: 62 EDLKDAQEKLELTEKKASDAEGDVAALNRRIQLVEEELDRAQERLATALQKLEE 115
E++K +KL+ E +A AE VA L + I +E++L +E + L++
Sbjct: 187 EEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDKLKCTKEEHLCTQRMLDQ 240
Score = 36.6 bits (83), Expect = 0.026
Identities = 35/153 (22%), Positives = 71/153 (46%), Gaps = 28/153 (18%)
Query: 16 ENAIDRAEQAEADKKAAEDKCKQVEE--ELTHLQ-KKLKGTEDELD-KYSE--------- 62
E A A+++E K E++ + EE EL +Q K+ K +E D KY E
Sbjct: 78 EEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIE 137
Query: 63 -DLKDAQEKLELTEKKASDAEGDVAALNRRIQLV--------------EEELDRAQERLA 107
DL+ +E+ EL E + + + + +++ ++ + EEE+ ++L
Sbjct: 138 GDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKILTDKLK 197
Query: 108 TALQKLEEAEKAADESERGMKVIENRAMKDEEK 140
A + E AE++ + E+ + +E++ +E+
Sbjct: 198 EAETRAEFAERSVAKLEKTIDDLEDKLKCTKEE 230
>gi|114155146 tropomyosin 3 isoform 3 [Homo sapiens]
Length = 247
Score = 306 bits (784), Expect = 1e-83
Identities = 160/236 (67%), Positives = 195/236 (82%)
Query: 46 LQKKLKGTEDELDKYSEDLKDAQEKLELTEKKASDAEGDVAALNRRIQLVEEELDRAQER 105
+++K++ + + D E + Q ++E + AE +VA+LNRRIQLVEEELDRAQER
Sbjct: 10 VKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQER 69
Query: 106 LATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEV 165
LATALQKLEEAEKAADESERGMKVIENRA+KDEEKME+QE+QLKEAKHIAEEADRKYEEV
Sbjct: 70 LATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEV 129
Query: 166 ARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEI 225
ARKLVI+EG+LER EERAE++E +C +++E+++ + NLK L AA EKYS+KEDKYEEEI
Sbjct: 130 ARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEI 189
Query: 226 KLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQTLNEL 281
K+L+DKLKEAETRAEFAER+VAKLEKTIDDLEE+L E N L L TL++L
Sbjct: 190 KILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLERNRLLSNELKLTLHDL 245
Score = 54.7 bits (130), Expect = 9e-08
Identities = 35/161 (21%), Positives = 79/161 (49%)
Query: 124 ERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAEERA 183
+R ++V++ +A EE+ E + +++ + E+A+ + + R++ ++E EL+RA+ER
Sbjct: 11 KRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERL 70
Query: 184 EVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFAE 243
+ K + E+ +K +E + K EK + E ++K +EA+ + E
Sbjct: 71 ATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVA 130
Query: 244 RTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQTLNELNCI 284
R + +E ++ EE+ A+ + + + L C+
Sbjct: 131 RKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCL 171
Score = 42.4 bits (98), Expect = 5e-04
Identities = 28/98 (28%), Positives = 48/98 (48%)
Query: 163 EEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYE 222
E V RK+ +L+ + + AEERAE + + + + SL + E+ D+ +
Sbjct: 8 EAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQ 67
Query: 223 EEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKL 260
E + KL+EAE A+ +ER + +E EEK+
Sbjct: 68 ERLATALQKLEEAEKAADESERGMKVIENRALKDEEKM 105
Score = 41.6 bits (96), Expect = 8e-04
Identities = 39/166 (23%), Positives = 74/166 (44%), Gaps = 28/166 (16%)
Query: 16 ENAIDRAEQAEADKKAAEDKCKQVEE--ELTHLQ-KKLKGTEDELD-KYSE--------- 62
E A A+++E K E++ + EE EL +Q K+ K +E D KY E
Sbjct: 78 EEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIE 137
Query: 63 -DLKDAQEKLELTEKKASDAEGDVAALNRRIQLV--------------EEELDRAQERLA 107
DL+ +E+ EL E + + + + +++ ++ + EEE+ ++L
Sbjct: 138 GDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKILTDKLK 197
Query: 108 TALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKH 153
A + E AE++ + E+ + +E R E+ + +LK H
Sbjct: 198 EAETRAEFAERSVAKLEKTIDDLEERLYSQLERNRLLSNELKLTLH 243
Score = 28.1 bits (61), Expect = 9.1
Identities = 14/81 (17%), Positives = 40/81 (49%)
Query: 197 LKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDL 256
++ V ++ L+ ++ E+ ++ + E++ ++AE R + +E+ +D
Sbjct: 7 IEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRA 66
Query: 257 EEKLAQAKEENVGLHQTLDQT 277
+E+LA A ++ + D++
Sbjct: 67 QERLATALQKLEEAEKAADES 87
>gi|224922812 tropomyosin 2 (beta) isoform 3 [Homo sapiens]
Length = 231
Score = 287 bits (735), Expect = 6e-78
Identities = 168/282 (59%), Positives = 198/282 (70%), Gaps = 53/282 (18%)
Query: 1 MEAIKKKMQMLKLDKENAIDRAEQAEADKKAAEDKCKQVEEELTHLQKKLKGTEDELDKY 60
M+AIKKKMQMLKLDKENAI D+ +Q E
Sbjct: 1 MDAIKKKMQMLKLDKENAI--------------DRAEQAEA------------------- 27
Query: 61 SEDLKDAQEKLELTEKKASDAEGDVAALNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
D K A+++ + E++ AL ++++ E+E++ K E+EKAA
Sbjct: 28 --DKKQAEDRCKQLEEEQQ-------ALQKKLKGTEDEVE-----------KYSESEKAA 67
Query: 121 DESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAE 180
DESERGMKVIENRAMKDEEKME+QEMQLKEAKHIAE++DRKYEEVARKLVILEGELER+E
Sbjct: 68 DESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSE 127
Query: 181 ERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAE 240
ERAEV+E + LEEEL+ + LKSL A+ E+YS KEDKYEEEIKLL +KLKEAETRAE
Sbjct: 128 ERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAE 187
Query: 241 FAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQTLNELN 282
FAER+VAKLEKTIDDLEE LA AKEENV +HQTLDQTL ELN
Sbjct: 188 FAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLLELN 229
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 88.6 bits (218), Expect = 6e-18
Identities = 60/257 (23%), Positives = 128/257 (49%), Gaps = 6/257 (2%)
Query: 6 KKMQMLKLDKENAIDRAEQAEADKKAAEDKCKQVEEELTHLQKKLKGTEDELDKYSEDLK 65
++ + + +KE + R E+ +K E+K +++EE++ H Q+K++ E E + E+
Sbjct: 319 RRQEEMMWEKEEKMRRQEEMMWEK---EEKIRELEEKM-HEQEKIR--EQEEKRQEEEKI 372
Query: 66 DAQEKLELTEKKASDAEGDVAALNRRIQLVEEELDRAQERLATALQKLEEAEKAADESER 125
QEK + E K E + +I+ EE + +E++ +K+ E E+ E E
Sbjct: 373 REQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEE 432
Query: 126 GMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAEERAEV 185
M+ E + + E+K+ QE +++E + + +E + K E K+ E +++ EE+
Sbjct: 433 KMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRR 492
Query: 186 SELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFAERT 245
E K + E++++ ++ E ++ EK + EE++ +K++E E + E
Sbjct: 493 QEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEK 552
Query: 246 VAKLEKTIDDLEEKLAQ 262
+ + E + EEK+ +
Sbjct: 553 MREQEVRLRQQEEKMQE 569
Score = 80.5 bits (197), Expect = 2e-15
Identities = 56/273 (20%), Positives = 133/273 (48%), Gaps = 10/273 (3%)
Query: 1 MEAIKKKMQMLKLDKENAIDRAEQAEADKK-AAEDKCKQVEEELTHLQKKLKGTEDELDK 59
++++ K+Q ++++ +R Q + +K E+K ++ EE++ ++K++ E+++ +
Sbjct: 262 LQSVSAKLQA-QVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRR 320
Query: 60 YSEDLKDAQEKLELTEKKASDAEGDVAALNRRIQLVEEELDRAQERLATALQKLEEAEKA 119
E + + +EK+ E+ + E + L ++ E+E R QE +K+ E EK
Sbjct: 321 QEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMH--EQEKIREQEEKRQEEEKIREQEKR 378
Query: 120 ADES------ERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILE 173
++ E ++ E + + EE M+ QE ++ E + E + + +E K+ E
Sbjct: 379 QEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQE 438
Query: 174 GELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLK 233
++ E++ E K + EE ++ + E + K + EE+++ +K++
Sbjct: 439 EKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIR 498
Query: 234 EAETRAEFAERTVAKLEKTIDDLEEKLAQAKEE 266
E E + E + + E+ + + EEK+ + +E+
Sbjct: 499 EQEKKIREQEEKIREQEEMMQEQEEKMWEQEEK 531
Score = 80.5 bits (197), Expect = 2e-15
Identities = 59/270 (21%), Positives = 134/270 (49%), Gaps = 10/270 (3%)
Query: 2 EAIKKKMQMLKLDKENAIDRAEQAEADKKAAEDKCKQVEEELTHLQKKLKGTEDELDKYS 61
E I+++ + ++ ++E + R E+ +K E+K ++ EE + ++K++ E+++ +
Sbjct: 302 EKIQEQEEKIR-EQEEKMRRQEEMMWEK---EEKMRRQEEMMWEKEEKIRELEEKMHE-Q 356
Query: 62 EDLKDAQEKLELTEK-----KASDAEGDVAALNRRIQLVEEELDRAQERLATALQKLEEA 116
E +++ +EK + EK K + E + +I+ EE++ +E + +K+ E
Sbjct: 357 EKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQ 416
Query: 117 EKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGEL 176
E+ E E M+ E + + EEK+ QE +++E + E + +E K+ EG++
Sbjct: 417 EEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKM 476
Query: 177 ERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAE 236
E + + E K EE+++ ++ E + E + EE++ +K+ E E
Sbjct: 477 CEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQE 536
Query: 237 TRAEFAERTVAKLEKTIDDLEEKLAQAKEE 266
+ + E + + E+ + + E +L Q +E+
Sbjct: 537 EKMQEQEEKMRRQEEKMREQEVRLRQQEEK 566
Score = 78.6 bits (192), Expect = 6e-15
Identities = 52/239 (21%), Positives = 112/239 (46%)
Query: 2 EAIKKKMQMLKLDKENAIDRAEQAEADKKAAEDKCKQVEEELTHLQKKLKGTEDELDKYS 61
E ++++ +M+ +E + E+ +K E + K+ EEE Q+K + E ++ +
Sbjct: 330 EKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQE 389
Query: 62 EDLKDAQEKLELTEKKASDAEGDVAALNRRIQLVEEELDRAQERLATALQKLEEAEKAAD 121
E +++ +EK+ E+ + E + ++ EEE+ +E++ +K+ E EK
Sbjct: 390 EKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIR 449
Query: 122 ESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAEE 181
E E ++ E + EEKM QE ++ E + +E + K K+ E ++ EE
Sbjct: 450 EQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEE 509
Query: 182 RAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAE 240
+ E + EE++ + E ++ EK + EE+++ +L++ E + +
Sbjct: 510 KIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEVRLRQQEEKMQ 568
Score = 77.4 bits (189), Expect = 1e-14
Identities = 62/263 (23%), Positives = 120/263 (45%), Gaps = 14/263 (5%)
Query: 7 KMQMLKLDKENAIDRAEQAEADKKAAEDKCKQVEEELTHLQKKLKGTED----ELDKYSE 62
K + KL ++ + +E++E E K K +L Q++L+ D EL S
Sbjct: 208 KEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSA 267
Query: 63 DLKDAQEKLELTEKKASDAEGDVAALNRRIQLVEEELDRAQERLATALQKLEEAEKAADE 122
L+ E+ EL + E + +IQ EE++ +E++ +K+ E+ E
Sbjct: 268 KLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWE 327
Query: 123 SERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAEER 182
E M+ E + EEK+ E ++ E + I E+ +++ EE E R +E+
Sbjct: 328 KEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEE----------EKIREQEK 377
Query: 183 AEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFA 242
+ E K EE+++ ++ E ++ EK + EE++ ++++E E +
Sbjct: 378 RQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQ 437
Query: 243 ERTVAKLEKTIDDLEEKLAQAKE 265
E + + EK I + EEK+ + +E
Sbjct: 438 EEKIREQEKKIREQEEKIREQEE 460
Score = 77.0 bits (188), Expect = 2e-14
Identities = 62/285 (21%), Positives = 129/285 (45%), Gaps = 20/285 (7%)
Query: 1 MEAIKKKMQMLKLDKENAIDRAEQAEADKKAAEDKCK-QVEEELTHLQKKLKGTEDE-LD 58
++ +K+K++ KL +AE K+ K Q + E L +L ++E +
Sbjct: 232 VKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMW 291
Query: 59 KYSEDLKDAQEKLELTEKKASDAEGDVAALNRRIQLVEEELDRAQERLATALQKLEEAEK 118
+ E +++ +EK++ E+K + E + + EE++ R +E + +K+ E E+
Sbjct: 292 RQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEE 351
Query: 119 AADESERGMKVIENR------------------AMKDEEKMEIQEMQLKEAKHIAEEADR 160
E E+ + E R + EEK+ QE +++E + + +E +
Sbjct: 352 KMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEE 411
Query: 161 KYEEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDK 220
K E K+ E E++ EE+ E K + E++++ ++ E ++ EK +
Sbjct: 412 KMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGE 471
Query: 221 YEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKE 265
E ++ K++E E + E + + EK I + EEK+ + +E
Sbjct: 472 QEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEE 516
Score = 69.7 bits (169), Expect = 3e-12
Identities = 47/216 (21%), Positives = 105/216 (48%), Gaps = 3/216 (1%)
Query: 2 EAIKKKMQMLKLDKENAI---DRAEQAEADKKAAEDKCKQVEEELTHLQKKLKGTEDELD 58
E K + Q K +E I ++ ++ EA E+K ++ EE++ ++ ++ E+++
Sbjct: 355 EQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMG 414
Query: 59 KYSEDLKDAQEKLELTEKKASDAEGDVAALNRRIQLVEEELDRAQERLATALQKLEEAEK 118
+ E + + +E+++ E+K E + ++I+ EE++ +E + +K+ E E
Sbjct: 415 EQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEG 474
Query: 119 AADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELER 178
E E M+ E + + EEK+ QE +++E + E + +E K+ E ++
Sbjct: 475 KMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCE 534
Query: 179 AEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKY 214
EE+ + E K EE+++ L+ E +++
Sbjct: 535 QEEKMQEQEEKMRRQEEKMREQEVRLRQQEEKMQEH 570
Score = 67.0 bits (162), Expect = 2e-11
Identities = 45/216 (20%), Positives = 107/216 (49%), Gaps = 8/216 (3%)
Query: 14 DKENAIDRAEQAEADKKAAEDKCKQVEE-ELTHLQKKLKGTEDELDKYSEDLKDAQEKLE 72
++E ++ E+ + ++K E + +Q +E ++ ++K++ E+++ + E +++ +EK+
Sbjct: 355 EQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMG 414
Query: 73 LTEKKASDAEGDVAALNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGM----- 127
E+K + E ++ +++ EE++ ++++ +K+ E E+ E E M
Sbjct: 415 EQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEG 474
Query: 128 KVIENRA--MKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAEERAEV 185
K+ E A + EEKM QE +++E + E + K E + E ++ EE+
Sbjct: 475 KMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCE 534
Query: 186 SELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKY 221
E K + EE+++ ++ E + EK ++
Sbjct: 535 QEEKMQEQEEKMRRQEEKMREQEVRLRQQEEKMQEH 570
Score = 60.1 bits (144), Expect = 2e-09
Identities = 60/258 (23%), Positives = 117/258 (45%), Gaps = 27/258 (10%)
Query: 29 KKAAEDKCKQVEEELTHLQKKLKGTEDELDKYSEDLKDAQEKLELTEKKASDAEGDVAAL 88
KK A+ +++ +E L +L ++ E QEKL+L E + S+ + +V L
Sbjct: 176 KKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKEL 235
Query: 89 NRRIQLVEEELDRAQ------------ERLATALQKLE-EAEKAADESE---RGMKVIEN 132
R +L+RA+ + L LQ + + + +E+E R + E
Sbjct: 236 KR-------KLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEE 288
Query: 133 RAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAEERAEVSELKCGD 192
+ + EEK++ +E +++E + E + K + E ++ R EE E K +
Sbjct: 289 KMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRE 348
Query: 193 LEEEL--KNVTNNLKSLEAASEKYSEKEDKYEEEIKL--LSDKLKEAETRAEFAERTVAK 248
LEE++ + + EK E+E + E+E K+ +K++E E + E + +
Sbjct: 349 LEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQE 408
Query: 249 LEKTIDDLEEKLAQAKEE 266
E+ + + EEK+ + +EE
Sbjct: 409 QEEKMGEQEEKMWEQEEE 426
Score = 50.8 bits (120), Expect = 1e-06
Identities = 31/142 (21%), Positives = 68/142 (47%)
Query: 1 MEAIKKKMQMLKLDKENAIDRAEQAEADKKAAEDKCKQVEEELTHLQKKLKGTEDELDKY 60
M+ ++KM+ + + + E + E+ ++ EE++ + K+ E ++ +
Sbjct: 427 MQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQ 486
Query: 61 SEDLKDAQEKLELTEKKASDAEGDVAALNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
E ++ +EK+ EKK + E + +Q EE++ +E++ +K++E E+
Sbjct: 487 EEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKM 546
Query: 121 DESERGMKVIENRAMKDEEKME 142
E M+ E R + EEKM+
Sbjct: 547 RRQEEKMREQEVRLRQQEEKMQ 568
Score = 36.2 bits (82), Expect = 0.034
Identities = 33/161 (20%), Positives = 73/161 (45%), Gaps = 23/161 (14%)
Query: 114 EEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILE 173
E+ +KA+ + + ++ ++ + Q+ +L+ A + ++ A ++ E AR L+
Sbjct: 96 EDEQKASHQHQEALRRELEAQVQTIRILTCQKTELQMALYYSQHAVKQLEGEARDLI--- 152
Query: 174 GELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKY----------EE 223
R S G+LE+ L V K + E+ +++ D +E
Sbjct: 153 -------SRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDE 205
Query: 224 EIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAK 264
E+K + KL+E + + E ++++ + +L+ KL +AK
Sbjct: 206 ELKEKNAKLQE---KLQLVESEKSEIQLNVKELKRKLERAK 243
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 82.8 bits (203), Expect = 3e-16
Identities = 59/271 (21%), Positives = 134/271 (49%), Gaps = 8/271 (2%)
Query: 2 EAIKKKMQMLKLDKENAI---DRAEQAEADKKAAEDKCKQVEEELTHLQKKLKGTEDELD 58
E K + Q K +E I ++ ++ EA E+K ++ EE++ ++K+ E+++
Sbjct: 449 EQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIH 508
Query: 59 KYS----EDLKDAQEKLELTEKKASDAEGDVAALNRRIQLVEEELDRAQERLATALQKLE 114
+ E+ + QE++ E+K + E ++ +I EE++ + +E++ +K+
Sbjct: 509 EQEKIREEEKRQEQEEMWRQEEKIREQE-EIWRQKEKIHEQEEKIRKQEEKMWRQEEKMH 567
Query: 115 EAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEG 174
+ E+ E E + E + + EEK+ QE +++E + + +E + K E K+ E
Sbjct: 568 DQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEE 627
Query: 175 ELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKE 234
+++ EE+ E K + E++++ ++ E ++ EK + EE++ +K++E
Sbjct: 628 KMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQE 687
Query: 235 AETRAEFAERTVAKLEKTIDDLEEKLAQAKE 265
E + E + + E + EEK+ + +E
Sbjct: 688 QEEKMRRQEEKMWEQEVRLRQQEEKMQEHQE 718
Score = 81.6 bits (200), Expect = 7e-16
Identities = 65/274 (23%), Positives = 130/274 (47%), Gaps = 22/274 (8%)
Query: 2 EAIKKKMQMLKLDKENAIDRAEQAEADKKAAEDKCKQVEEELTHLQKKLKGTEDELDKYS 61
E ++++ +M+ +E + E+ +K E + K+ EEE Q+K + E ++ +
Sbjct: 424 EKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQE 483
Query: 62 EDLKDAQEKLELTEKKASDAEGDVAALNRRIQLVEEELDRAQERLATALQKLEEAEKA-- 119
E +++ +EK+ E+K E + + + ++ EEE + QE + +K+ E E+
Sbjct: 484 EKIREQEEKIREQEEKMWRQEEKI---HEQEKIREEEKRQEQEEMWRQEEKIREQEEIWR 540
Query: 120 ----ADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGE 175
E E ++ E + + EEKM QE +++E + + K E K+ E +
Sbjct: 541 QKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEK 600
Query: 176 LERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDK---YEEEIKLLSDKL 232
+ EE + E K G+ EE++ EK E+E+K EE+I+ K+
Sbjct: 601 IREQEEMTQEQEEKMGEQEEKMCE----------QEEKMQEQEEKMRRQEEKIREQEKKI 650
Query: 233 KEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEE 266
+E E + E + + E+ + + EEK+ + +E+
Sbjct: 651 REQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEK 684
Score = 80.5 bits (197), Expect = 2e-15
Identities = 56/250 (22%), Positives = 122/250 (48%), Gaps = 19/250 (7%)
Query: 2 EAIKKKMQMLKLDKENAIDRAEQAEADKKAAEDKCKQVEEELTHLQKKLKGTED------ 55
E I+++ + ++ +E + E+ +K E++ +Q +EE+ ++K++ E+
Sbjct: 484 EKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKE 543
Query: 56 ELDKYSEDLKDAQEKLELTEKKASDAEGDVAALNRRIQLVEEELDRAQERLATALQKLEE 115
++ + E ++ +EK+ E+K D E + ++ EE++ +E++ +K+ E
Sbjct: 544 KIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIRE 603
Query: 116 AEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGE 175
E+ E E M E + + EEKM+ QE +++ + E ++K E K+ E
Sbjct: 604 QEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEM 663
Query: 176 LERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDK-YEEEIKL--LSDKL 232
++ EE+ E K + EE+ ++ EK +E+K +E+E++L +K+
Sbjct: 664 MQEQEEKMWEQEEKMCEQEEK----------MQEQEEKMRRQEEKMWEQEVRLRQQEEKM 713
Query: 233 KEAETRAEFA 242
+E + E A
Sbjct: 714 QEHQEHLEAA 723
Score = 72.8 bits (177), Expect = 3e-13
Identities = 62/297 (20%), Positives = 136/297 (45%), Gaps = 34/297 (11%)
Query: 1 MEAIKKKMQMLKLDKENAIDRAEQAEADKK-AAEDKCKQVEEELTHLQKKLKGTEDELDK 59
++++ K+Q ++++ +R Q + +K E+K ++ EE++ ++K++ E+++ +
Sbjct: 335 LQSVSAKLQA-QVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIRE 393
Query: 60 YSEDLK---------------------DAQEKLELTEKKASDAEGDVAALNRRIQLVEEE 98
E ++ + +EK+ E+ + E + L ++ E+E
Sbjct: 394 QEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMH--EQE 451
Query: 99 LDRAQERLATALQKLEEAEKAADE------SERGMKVIENRAMKDEEKMEIQEMQLKEAK 152
R QE +K+ E EK ++ E ++ E + + EEKM QE ++ E +
Sbjct: 452 KIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQE 511
Query: 153 HIAEEADRKYEEV---ARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEA 209
I EE R+ +E + + + E+ R +E+ E K EE++ + E
Sbjct: 512 KIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEE 571
Query: 210 ASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEE 266
+ EK + EE+I+ +K++E E + E + E+ + + EEK+ + +E+
Sbjct: 572 KIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEK 628
Score = 67.4 bits (163), Expect = 1e-11
Identities = 64/247 (25%), Positives = 121/247 (48%), Gaps = 35/247 (14%)
Query: 37 KQVEEELTHLQKKLKGTEDELDKYSEDLKDAQEKLE----LTEKKASDAEGD-----VAA 87
++++E+ LQ+KL+ E E + ++K+ + KLE L ++ AE D + +
Sbjct: 278 EELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQS 337
Query: 88 LNRRIQLVEEELD-------RAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEK 140
++ ++Q EE + + +E++ +K++E E+ E E ++ E + + EEK
Sbjct: 338 VSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEK 397
Query: 141 MEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAEERAEVSELKCGDLEEELKNV 200
M QE + E EE R+ EE+ + E ++ R EE E K +LEE++
Sbjct: 398 MRRQEEMMWE----KEEKMRRQEEMMWE---KEEKMRRQEEMMWEKEEKIRELEEKMHE- 449
Query: 201 TNNLKSLEAASEKYSEKEDKYEEEIKLL-SDKLKEAETRAEFAERTVAKLEKTIDDLEEK 259
EK E+E+K +EE K+ +K +E E + E + + E+ I + EEK
Sbjct: 450 ----------QEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEK 499
Query: 260 LAQAKEE 266
+ + +E+
Sbjct: 500 MWRQEEK 506
Score = 65.9 bits (159), Expect = 4e-11
Identities = 68/295 (23%), Positives = 128/295 (43%), Gaps = 34/295 (11%)
Query: 4 IKKKMQMLKLDKENAIDRAEQAEADKKAAEDKC----KQVEEELTHLQKKLKGTEDELDK 59
+++K+Q+++ +K + E +K K +Q++ E HL K+L+ +L
Sbjct: 287 LQEKLQLVESEKSEI--QLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQA 344
Query: 60 YSEDLKDAQEKLELTEKKASDAEGDVAALNRRIQLVEEELDRAQERLATALQKLEEAEKA 119
E+ + + E+K E + +IQ EE++ +E++ +K+ E+
Sbjct: 345 QVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEM 404
Query: 120 ADESERGMKVIENRAMKDEEKMEIQE----------MQLKEAKH----IAEEADRKYEE- 164
E E M+ E + EEKM QE +L+E H I E+ +++ EE
Sbjct: 405 MWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEE 464
Query: 165 ---VARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLE--AASEKYSEKED 219
K E ++ R EE+ E K + EE++ + E EK E+E+
Sbjct: 465 KIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEE 524
Query: 220 KY--------EEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEE 266
+ +EEI +K+ E E + E + + E+ + D EEK+ + +E+
Sbjct: 525 MWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEK 579
Score = 37.4 bits (85), Expect = 0.015
Identities = 23/106 (21%), Positives = 53/106 (50%), Gaps = 7/106 (6%)
Query: 5 KKKMQMLKLDKENAIDRAEQAEADKKAAEDKCKQVEEELTHLQKKLKGTEDELDKYSEDL 64
++KMQ + ++ + E + E+K ++ EE + ++K+ E+++ + E +
Sbjct: 626 EEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKM 685
Query: 65 KDAQEKLELTEKKASDAEGDVAALNRRIQLVEEELDRAQERLATAL 110
++ +EK+ E+K + E R++ EE++ QE L A+
Sbjct: 686 QEQEEKMRRQEEKMWEQEV-------RLRQQEEKMQEHQEHLEAAI 724
Score = 35.4 bits (80), Expect = 0.057
Identities = 33/161 (20%), Positives = 72/161 (44%), Gaps = 23/161 (14%)
Query: 114 EEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILE 173
E+ +KA+ + + ++ + + Q+ +L+ A + ++ A ++ E AR L+
Sbjct: 169 EDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLI--- 225
Query: 174 GELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKY----------EE 223
R S G+LE+ L V K + E+ +++ D +E
Sbjct: 226 -------SRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDE 278
Query: 224 EIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAK 264
E+K + KL+E + + E ++++ + +L+ KL +AK
Sbjct: 279 ELKEKNAKLQE---KLQLVESEKSEIQLNVKELKRKLERAK 316
>gi|38044112 restin isoform b [Homo sapiens]
Length = 1392
Score = 81.6 bits (200), Expect = 7e-16
Identities = 74/294 (25%), Positives = 140/294 (47%), Gaps = 28/294 (9%)
Query: 5 KKKMQMLKLDKENAIDRAEQAEADKKAAEDKCKQVEEELTHLQKKLKGTEDELDKYSEDL 64
K +M+ L+ E A + + E +K A K + EL + KL ++ L + S+
Sbjct: 741 KSEMKKLRQQLEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTNLQENLSEVSQVK 800
Query: 65 KDAQEKLELTEKKASDAEGDVAALNRRIQLVEEELDRAQER---LATALQKLEE-----A 116
+ +++L++ ++K ++A + ++ R +Q +L + +E+ L++ L+KL E
Sbjct: 801 ETLEKELQILKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADME 860
Query: 117 EKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEAD------RKYEEVARKLV 170
K ++ ER ++I+ + + + EI +M + + + D R EE+ KL
Sbjct: 861 AKFREKDEREEQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERDVEELQLKLT 920
Query: 171 -------ILEGELERAEERAEVSELKCGDL-EEELKNVTNNLKSLEAASEKYSEKEDKYE 222
L+ +E +AE S+ + EEE K + L LE K E
Sbjct: 921 KANENASFLQKSIEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLE----KKMETSHNQC 976
Query: 223 EEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQ 276
+E+K ++ +ET+ + E + L+KT+ D E+KL A+EEN GL Q L++
Sbjct: 977 QELKARYERAT-SETKTKH-EEILQNLQKTLLDTEDKLKGAREENSGLLQELEE 1028
Score = 71.2 bits (173), Expect = 9e-13
Identities = 55/302 (18%), Positives = 139/302 (46%), Gaps = 21/302 (6%)
Query: 1 MEAIKKKMQMLK----LDKENAIDRAEQAEADKKAAE---DKCKQVEEELTHLQKKLKGT 53
+EAI+ K+ + ++ E+ +++ ++AE K E KC + + + + +LK T
Sbjct: 664 LEAIRSKLDKAEDQHLVEMEDTLNKLQEAEIKVKELEVLQAKCNEQTKVIDNFTSQLKAT 723
Query: 54 EDEL----------DKYSEDLKDAQEKLELTEKKASDAEGDVAALNRRIQLVEEELDRAQ 103
E++L + ++K +++LE EK+ E + A + + + EL +
Sbjct: 724 EEKLLDLDALRKASSEGKSEMKKLRQQLEAAEKQIKHLEIEKNAESSKASSITRELQGRE 783
Query: 104 ERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYE 163
+L + L E + + E+ +++++ + + E+ + ++E + + + ++
Sbjct: 784 LKLTNLQENLSEVSQVKETLEKELQILKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFN 843
Query: 164 EVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEE 223
++ L L L E + + + L + + + N++ + S S + K +
Sbjct: 844 MLSSDLEKLRENLADMEAKFREKDEREEQLIKAKEKLENDIAEIMKMSGDNSSQLTKMND 903
Query: 224 EIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEENVGLHQ----TLDQTLN 279
E++L ++E + + A + L+K+I+D+ K Q+++E H+ L++ L+
Sbjct: 904 ELRLKERDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKKHEEEKKELERKLS 963
Query: 280 EL 281
+L
Sbjct: 964 DL 965
Score = 62.0 bits (149), Expect = 6e-10
Identities = 61/268 (22%), Positives = 124/268 (46%), Gaps = 14/268 (5%)
Query: 16 ENAIDRAEQAEADKKAAEDKCKQVEE-ELTHLQKKLKGTEDELDKYSEDLKDAQEKLELT 74
E AI +QA + K + K E E L+ +++ + E+L++ Q+
Sbjct: 582 ETAIASHQQAMEELKVSFSKGLGTETAEFAELKTQIEKMRLDYQHEIENLQNQQDS---- 637
Query: 75 EKKASDAEGDVAALNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRA 134
++A+ A+ ++ AL ++ V +E + + E + + L K E+ E E + ++
Sbjct: 638 -ERAAHAK-EMEALRAKLMKVIKEKENSLEAIRSKLDKAEDQHLV--EMEDTLNKLQEAE 693
Query: 135 MKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAEERAEVSELKCGDLE 194
+K +E +E+ + + E + + + + KL+ L+ L +A + SE+K L
Sbjct: 694 IKVKE-LEVLQAKCNEQTKVIDNFTSQLKATEEKLLDLDA-LRKASSEGK-SEMK--KLR 748
Query: 195 EELKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTID 254
++L+ +K LE S K E++ KL + + LEK +
Sbjct: 749 QQLEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTNLQENLSEVSQVKETLEKELQ 808
Query: 255 DLEEKLAQAKEENVGLHQTLDQTLNELN 282
L+EK A+A EE V + +++ +T+N+L+
Sbjct: 809 ILKEKFAEASEEAVSVQRSMQETVNKLH 836
Score = 59.7 bits (143), Expect = 3e-09
Identities = 53/270 (19%), Positives = 122/270 (45%), Gaps = 27/270 (10%)
Query: 8 MQMLKLDKENAIDRAEQAEADKKAAEDKCKQVEEELTHLQKKLKGTEDELDKYSEDLKDA 67
M+ + +K + E + +++ ++E ++L +++ L ++ +++
Sbjct: 1049 MEQMTKEKTETLASLEDTKQTNAKLQNELDTLKENNLKNVEELNKSKELLTVENQKMEEF 1108
Query: 68 QEKLELTEKKASDAEGDVAALNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGM 127
++++E ++ A+ ++AL + EEL R+++ + T+ QKLEE + M
Sbjct: 1109 RKEIETLKQAAAQKSQQLSALQEENVKLAEELGRSRDEV-TSHQKLEEERSVLNNQLLEM 1167
Query: 128 KVIENRAMKD--EEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAEERAEV 185
K E++ +KD EEK +Q+ + + E D + E++ ++ +L GE A+ V
Sbjct: 1168 KKRESKFIKDADEEKASLQK-SISITSALLTEKDAELEKLRNEVTVLRGENASAKSLHSV 1226
Query: 186 S----------ELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEA 235
ELK +LE +LK L S ++ ++++++ +
Sbjct: 1227 VQTLESDKVKLELKVKNLELQLKENKRQLSSSSGNTDTQADEDERAQ------------- 1273
Query: 236 ETRAEFAERTVAKLEKTIDDLEEKLAQAKE 265
E++ +F + L++ DL+ K+ E
Sbjct: 1274 ESQIDFLNSVIVDLQRKNQDLKMKVEMMSE 1303
Score = 55.8 bits (133), Expect = 4e-08
Identities = 53/264 (20%), Positives = 123/264 (46%), Gaps = 13/264 (4%)
Query: 4 IKKKMQMLKLDKENAIDRAEQAEADKKAAEDKCKQVEEE-LTHLQKKLKGTEDELDKYSE 62
+++K+ L+ E + ++ ++ +A + A + K EE L +LQK L TED+L E
Sbjct: 958 LERKLSDLEKKMETSHNQCQELKARYERATSETKTKHEEILQNLQKTLLDTEDKLKGARE 1017
Query: 63 DLKDAQEKLELTEKKASDAEGDVAALNRRIQLVEEELDRAQERLATALQKLEEAEKAADE 122
+ ++LE K+A A+ A +Q++E+ E LA+ LE+ ++ +
Sbjct: 1018 ENSGLLQELEELRKQADKAKAAQTA-EDAMQIMEQMTKEKTETLAS----LEDTKQTNAK 1072
Query: 123 SERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAEER 182
+ + ++ +K+ E +L ++K + ++K EE +++ L+ + ++
Sbjct: 1073 LQNELDTLKENNLKNVE-------ELNKSKELLTVENQKMEEFRKEIETLKQAAAQKSQQ 1125
Query: 183 AEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFA 242
+ + L EEL + + S + E+ S ++ E K S +K+A+
Sbjct: 1126 LSALQEENVKLAEELGRSRDEVTSHQKLEEERSVLNNQLLEMKKRESKFIKDADEEKASL 1185
Query: 243 ERTVAKLEKTIDDLEEKLAQAKEE 266
+++++ + + + +L + + E
Sbjct: 1186 QKSISITSALLTEKDAELEKLRNE 1209
Score = 51.2 bits (121), Expect = 1e-06
Identities = 56/248 (22%), Positives = 105/248 (42%), Gaps = 36/248 (14%)
Query: 41 EELTHLQKKLKGTEDELDKYSEDLKDAQEKLELTEKKASDAEGDVAALNRRIQLVEEELD 100
E + +K+ GT E LK+ Q+ +E + +VA + +E+EL
Sbjct: 338 ETSSRYARKISGTT----ALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELA 393
Query: 101 RAQE-------RLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKH 153
A++ L + +L +AAD + +E +EEK +++++Q + +
Sbjct: 394 LARDGHDQHVLELEAKMDQLRTMVEAADREK-----VELLNQLEEEKRKVEDLQFRVEEE 448
Query: 154 IAEEADRKYEEVARKLVILEGELERAEERAEVSELK--------CGDLEEELKNVTNNLK 205
+ D + V+ K I+E E + A EV+EL+ GD++ L + L+
Sbjct: 449 SITKGDLEVATVSEKSRIMELEKDLALRVQEVAELRRRLESNKPAGDVDMSL----SLLQ 504
Query: 206 SLEAASEKYSEKEDKYEEEIKLLS------DKLKEAETRAEFAERTVAKLEKTIDDLEEK 259
+ + EK ++ EI L ++ + E +A + KL K + L+ K
Sbjct: 505 EISSLQEKLEVTRTDHQREITSLKEHFGAREETHQKEIKALYT--ATEKLSKENESLKSK 562
Query: 260 LAQAKEEN 267
L A +EN
Sbjct: 563 LEHANKEN 570
Score = 45.1 bits (105), Expect = 7e-05
Identities = 72/329 (21%), Positives = 134/329 (40%), Gaps = 66/329 (20%)
Query: 4 IKKKMQMLKLDKENA----IDRAEQAEADKKAAEDKCKQVEE------------------ 41
++ KM L+ E A ++ Q E +K+ ED +VEE
Sbjct: 406 LEAKMDQLRTMVEAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLEVATVSEKSR 465
Query: 42 -------------ELTHLQKKLK-----GTEDELDKYSEDLKDAQEKLELTEKKASDAEG 83
E+ L+++L+ G D +++ QEKLE+T +D +
Sbjct: 466 IMELEKDLALRVQEVAELRRRLESNKPAGDVDMSLSLLQEISSLQEKLEVTR---TDHQR 522
Query: 84 DVAALNRRIQLVEEELDRAQERLATALQKL-EEAEKAADESERGMKVIENRAMKDEEKME 142
++ +L EE + + L TA +KL +E E + E K + + K+E
Sbjct: 523 EITSLKEHFGAREETHQKEIKALYTATEKLSKENESLKSKLEHANKENSDVIALWKSKLE 582
Query: 143 ---------IQEMQLKEAKHIAEEADRKYE---EVARKLVILEGELERAEERAEVSELKC 190
++E+++ +K + E E ++ + + + E+E + + + SE
Sbjct: 583 TAIASHQQAMEELKVSFSKGLGTETAEFAELKTQIEKMRLDYQHEIENLQNQQD-SERAA 641
Query: 191 GDLEEE------LKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFAER 244
E E +K + SLEA K + ED++ E++ +KL+EAE + + E
Sbjct: 642 HAKEMEALRAKLMKVIKEKENSLEAIRSKLDKAEDQHLVEMEDTLNKLQEAEIKVKELEV 701
Query: 245 TVAKLE---KTIDDLEEKLAQAKEENVGL 270
AK K ID+ +L +E+ + L
Sbjct: 702 LQAKCNEQTKVIDNFTSQLKATEEKLLDL 730
Score = 44.7 bits (104), Expect = 9e-05
Identities = 41/165 (24%), Positives = 79/165 (47%), Gaps = 13/165 (7%)
Query: 1 MEAIKKKMQMLKLDKENAIDRAEQAEADKKAAEDKCKQV---EEELTHLQKKLKGTEDEL 57
+E + K ++L ++ + + ++ E K+AA K +Q+ +EE L ++L + DE+
Sbjct: 1088 VEELNKSKELLTVENQKMEEFRKEIETLKQAAAQKSQQLSALQEENVKLAEELGRSRDEV 1147
Query: 58 ---DKYSEDLKDAQEKLELTEKKAS----DAEGDVAALNRRIQLVEE---ELDRAQERLA 107
K E+ +L +K+ S DA+ + A+L + I + E D E+L
Sbjct: 1148 TSHQKLEEERSVLNNQLLEMKKRESKFIKDADEEKASLQKSISITSALLTEKDAELEKLR 1207
Query: 108 TALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAK 152
+ L +A ++ +E+ +K E K++ E+QLKE K
Sbjct: 1208 NEVTVLRGENASAKSLHSVVQTLESDKVKLELKVKNLELQLKENK 1252
>gi|4506751 restin isoform a [Homo sapiens]
Length = 1427
Score = 81.6 bits (200), Expect = 7e-16
Identities = 74/294 (25%), Positives = 140/294 (47%), Gaps = 28/294 (9%)
Query: 5 KKKMQMLKLDKENAIDRAEQAEADKKAAEDKCKQVEEELTHLQKKLKGTEDELDKYSEDL 64
K +M+ L+ E A + + E +K A K + EL + KL ++ L + S+
Sbjct: 776 KSEMKKLRQQLEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTNLQENLSEVSQVK 835
Query: 65 KDAQEKLELTEKKASDAEGDVAALNRRIQLVEEELDRAQER---LATALQKLEE-----A 116
+ +++L++ ++K ++A + ++ R +Q +L + +E+ L++ L+KL E
Sbjct: 836 ETLEKELQILKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADME 895
Query: 117 EKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEAD------RKYEEVARKLV 170
K ++ ER ++I+ + + + EI +M + + + D R EE+ KL
Sbjct: 896 AKFREKDEREEQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERDVEELQLKLT 955
Query: 171 -------ILEGELERAEERAEVSELKCGDL-EEELKNVTNNLKSLEAASEKYSEKEDKYE 222
L+ +E +AE S+ + EEE K + L LE K E
Sbjct: 956 KANENASFLQKSIEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLE----KKMETSHNQC 1011
Query: 223 EEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQ 276
+E+K ++ +ET+ + E + L+KT+ D E+KL A+EEN GL Q L++
Sbjct: 1012 QELKARYERAT-SETKTKH-EEILQNLQKTLLDTEDKLKGAREENSGLLQELEE 1063
Score = 71.2 bits (173), Expect = 9e-13
Identities = 55/302 (18%), Positives = 139/302 (46%), Gaps = 21/302 (6%)
Query: 1 MEAIKKKMQMLK----LDKENAIDRAEQAEADKKAAE---DKCKQVEEELTHLQKKLKGT 53
+EAI+ K+ + ++ E+ +++ ++AE K E KC + + + + +LK T
Sbjct: 699 LEAIRSKLDKAEDQHLVEMEDTLNKLQEAEIKVKELEVLQAKCNEQTKVIDNFTSQLKAT 758
Query: 54 EDEL----------DKYSEDLKDAQEKLELTEKKASDAEGDVAALNRRIQLVEEELDRAQ 103
E++L + ++K +++LE EK+ E + A + + + EL +
Sbjct: 759 EEKLLDLDALRKASSEGKSEMKKLRQQLEAAEKQIKHLEIEKNAESSKASSITRELQGRE 818
Query: 104 ERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYE 163
+L + L E + + E+ +++++ + + E+ + ++E + + + ++
Sbjct: 819 LKLTNLQENLSEVSQVKETLEKELQILKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFN 878
Query: 164 EVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEE 223
++ L L L E + + + L + + + N++ + S S + K +
Sbjct: 879 MLSSDLEKLRENLADMEAKFREKDEREEQLIKAKEKLENDIAEIMKMSGDNSSQLTKMND 938
Query: 224 EIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEENVGLHQ----TLDQTLN 279
E++L ++E + + A + L+K+I+D+ K Q+++E H+ L++ L+
Sbjct: 939 ELRLKERDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKKHEEEKKELERKLS 998
Query: 280 EL 281
+L
Sbjct: 999 DL 1000
Score = 62.0 bits (149), Expect = 6e-10
Identities = 61/268 (22%), Positives = 124/268 (46%), Gaps = 14/268 (5%)
Query: 16 ENAIDRAEQAEADKKAAEDKCKQVEE-ELTHLQKKLKGTEDELDKYSEDLKDAQEKLELT 74
E AI +QA + K + K E E L+ +++ + E+L++ Q+
Sbjct: 617 ETAIASHQQAMEELKVSFSKGLGTETAEFAELKTQIEKMRLDYQHEIENLQNQQDS---- 672
Query: 75 EKKASDAEGDVAALNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRA 134
++A+ A+ ++ AL ++ V +E + + E + + L K E+ E E + ++
Sbjct: 673 -ERAAHAK-EMEALRAKLMKVIKEKENSLEAIRSKLDKAEDQHLV--EMEDTLNKLQEAE 728
Query: 135 MKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAEERAEVSELKCGDLE 194
+K +E +E+ + + E + + + + KL+ L+ L +A + SE+K L
Sbjct: 729 IKVKE-LEVLQAKCNEQTKVIDNFTSQLKATEEKLLDLDA-LRKASSEGK-SEMK--KLR 783
Query: 195 EELKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTID 254
++L+ +K LE S K E++ KL + + LEK +
Sbjct: 784 QQLEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTNLQENLSEVSQVKETLEKELQ 843
Query: 255 DLEEKLAQAKEENVGLHQTLDQTLNELN 282
L+EK A+A EE V + +++ +T+N+L+
Sbjct: 844 ILKEKFAEASEEAVSVQRSMQETVNKLH 871
Score = 59.7 bits (143), Expect = 3e-09
Identities = 53/270 (19%), Positives = 122/270 (45%), Gaps = 27/270 (10%)
Query: 8 MQMLKLDKENAIDRAEQAEADKKAAEDKCKQVEEELTHLQKKLKGTEDELDKYSEDLKDA 67
M+ + +K + E + +++ ++E ++L +++ L ++ +++
Sbjct: 1084 MEQMTKEKTETLASLEDTKQTNAKLQNELDTLKENNLKNVEELNKSKELLTVENQKMEEF 1143
Query: 68 QEKLELTEKKASDAEGDVAALNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGM 127
++++E ++ A+ ++AL + EEL R+++ + T+ QKLEE + M
Sbjct: 1144 RKEIETLKQAAAQKSQQLSALQEENVKLAEELGRSRDEV-TSHQKLEEERSVLNNQLLEM 1202
Query: 128 KVIENRAMKD--EEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAEERAEV 185
K E++ +KD EEK +Q+ + + E D + E++ ++ +L GE A+ V
Sbjct: 1203 KKRESKFIKDADEEKASLQK-SISITSALLTEKDAELEKLRNEVTVLRGENASAKSLHSV 1261
Query: 186 S----------ELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEA 235
ELK +LE +LK L S ++ ++++++ +
Sbjct: 1262 VQTLESDKVKLELKVKNLELQLKENKRQLSSSSGNTDTQADEDERAQ------------- 1308
Query: 236 ETRAEFAERTVAKLEKTIDDLEEKLAQAKE 265
E++ +F + L++ DL+ K+ E
Sbjct: 1309 ESQIDFLNSVIVDLQRKNQDLKMKVEMMSE 1338
Score = 55.8 bits (133), Expect = 4e-08
Identities = 53/264 (20%), Positives = 123/264 (46%), Gaps = 13/264 (4%)
Query: 4 IKKKMQMLKLDKENAIDRAEQAEADKKAAEDKCKQVEEE-LTHLQKKLKGTEDELDKYSE 62
+++K+ L+ E + ++ ++ +A + A + K EE L +LQK L TED+L E
Sbjct: 993 LERKLSDLEKKMETSHNQCQELKARYERATSETKTKHEEILQNLQKTLLDTEDKLKGARE 1052
Query: 63 DLKDAQEKLELTEKKASDAEGDVAALNRRIQLVEEELDRAQERLATALQKLEEAEKAADE 122
+ ++LE K+A A+ A +Q++E+ E LA+ LE+ ++ +
Sbjct: 1053 ENSGLLQELEELRKQADKAKAAQTA-EDAMQIMEQMTKEKTETLAS----LEDTKQTNAK 1107
Query: 123 SERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAEER 182
+ + ++ +K+ E +L ++K + ++K EE +++ L+ + ++
Sbjct: 1108 LQNELDTLKENNLKNVE-------ELNKSKELLTVENQKMEEFRKEIETLKQAAAQKSQQ 1160
Query: 183 AEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFA 242
+ + L EEL + + S + E+ S ++ E K S +K+A+
Sbjct: 1161 LSALQEENVKLAEELGRSRDEVTSHQKLEEERSVLNNQLLEMKKRESKFIKDADEEKASL 1220
Query: 243 ERTVAKLEKTIDDLEEKLAQAKEE 266
+++++ + + + +L + + E
Sbjct: 1221 QKSISITSALLTEKDAELEKLRNE 1244
Score = 45.1 bits (105), Expect = 7e-05
Identities = 44/171 (25%), Positives = 78/171 (45%), Gaps = 11/171 (6%)
Query: 95 VEEELDRAQERLATALQK--LEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLK--E 150
++E L Q+ + L + LE AE A S G E +D + E++ K +
Sbjct: 353 LQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALARDGHDQHVLELEAKMDQ 412
Query: 151 AKHIAEEADRKYEEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAA 210
+ + E ADR+ E+ +L + ++E + R E + GDLE + K +K LE +
Sbjct: 413 LRTMVEAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLETQTKLEHARIKELEQS 472
Query: 211 SEKYSEKEDKYEEEIK-----LLSDKLKEAETRAEFAERT--VAKLEKTID 254
K DK + E++ +S+K + E + A R VA+L + ++
Sbjct: 473 LLFEKTKADKLQRELEDTRVATVSEKSRIMELEKDLALRVQEVAELRRRLE 523
Score = 44.7 bits (104), Expect = 9e-05
Identities = 41/165 (24%), Positives = 79/165 (47%), Gaps = 13/165 (7%)
Query: 1 MEAIKKKMQMLKLDKENAIDRAEQAEADKKAAEDKCKQV---EEELTHLQKKLKGTEDEL 57
+E + K ++L ++ + + ++ E K+AA K +Q+ +EE L ++L + DE+
Sbjct: 1123 VEELNKSKELLTVENQKMEEFRKEIETLKQAAAQKSQQLSALQEENVKLAEELGRSRDEV 1182
Query: 58 ---DKYSEDLKDAQEKLELTEKKAS----DAEGDVAALNRRIQLVEE---ELDRAQERLA 107
K E+ +L +K+ S DA+ + A+L + I + E D E+L
Sbjct: 1183 TSHQKLEEERSVLNNQLLEMKKRESKFIKDADEEKASLQKSISITSALLTEKDAELEKLR 1242
Query: 108 TALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAK 152
+ L +A ++ +E+ +K E K++ E+QLKE K
Sbjct: 1243 NEVTVLRGENASAKSLHSVVQTLESDKVKLELKVKNLELQLKENK 1287
Score = 42.4 bits (98), Expect = 5e-04
Identities = 72/340 (21%), Positives = 138/340 (40%), Gaps = 66/340 (19%)
Query: 4 IKKKMQMLKLDKENA----IDRAEQAEADKKAAEDKCKQVEEE----------------- 42
++ KM L+ E A ++ Q E +K+ ED +VEEE
Sbjct: 406 LEAKMDQLRTMVEAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLETQTKLEHAR 465
Query: 43 LTHLQKKLKGTEDELDKYSEDLKDAQEKLELTEKKASDAEGD-------VAALNRRIQLV 95
+ L++ L + + DK +L+D + + + + E D VA L RR++
Sbjct: 466 IKELEQSLLFEKTKADKLQRELEDTRVATVSEKSRIMELEKDLALRVQEVAELRRRLESN 525
Query: 96 EE--ELDRAQERLATALQKLEEAEKAADESERGMKVIENR--AMKDEEKMEIQ------E 145
+ ++D + L E+ E + +R + ++ A ++ + EI+ E
Sbjct: 526 KPAGDVDMSLSLLQEISSLQEKLEVTRTDHQREITSLKEHFGAREETHQKEIKALYTATE 585
Query: 146 MQLKEAKHIAEEADRKYEEVARKLVILEGELERA--------------------EERAEV 185
KE + + + + +E + + + + +LE A E AE
Sbjct: 586 KLSKENESLKSKLEHANKENSDVIALWKSKLETAIASHQQAMEELKVSFSKGLGTETAEF 645
Query: 186 SELKCG------DLEEELKNVTNNLKSLEAASEKYSEK-EDKYEEEIKLLSDKLKEAETR 238
+ELK D + E++N+ N S AA K E K + IK + L+ ++
Sbjct: 646 AELKTQIEKMRLDYQHEIENLQNQQDSERAAHAKEMEALRAKLMKVIKEKENSLEAIRSK 705
Query: 239 AEFAE-RTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQT 277
+ AE + + ++E T++ L+E + KE V + +QT
Sbjct: 706 LDKAEDQHLVEMEDTLNKLQEAEIKVKELEVLQAKCNEQT 745
Score = 36.2 bits (82), Expect = 0.034
Identities = 41/206 (19%), Positives = 86/206 (41%), Gaps = 13/206 (6%)
Query: 79 SDAEGDVAALNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDE 138
S V++ R L+ E R +++ L+EA K E+ + + A +D
Sbjct: 320 SSVASSVSSRPSRTGLLTETSSRYARKIS-GTTALQEALK-----EKQQHIEQLLAERDL 373
Query: 139 EKMEIQEMQLKEAKHIAE---EADRKYEEVARKLVILEGELERAEERAEVSELKCGDLEE 195
E+ E+ K H+ E E + + ++ LE ++++ E ++ + +L
Sbjct: 374 ERAEVA----KATSHVGEIEQELALARDGHDQHVLELEAKMDQLRTMVEAADREKVELLN 429
Query: 196 ELKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDD 255
+L+ ++ L+ E+ S + E + KL ++KE E F + KL++ ++D
Sbjct: 430 QLEEEKRKVEDLQFRVEEESITKGDLETQTKLEHARIKELEQSLLFEKTKADKLQRELED 489
Query: 256 LEEKLAQAKEENVGLHQTLDQTLNEL 281
K + L + L + E+
Sbjct: 490 TRVATVSEKSRIMELEKDLALRVQEV 515
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 81.3 bits (199), Expect = 9e-16
Identities = 61/277 (22%), Positives = 137/277 (49%), Gaps = 12/277 (4%)
Query: 7 KMQMLKLDKENAIDRAEQAEADKKAAEDKCKQVEEELTHLQKKLKGTEDELDKYSEDLKD 66
+ Q L KE ++ + E ++K E + K ++E Q+K ++++ + + + +
Sbjct: 431 QQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWE 490
Query: 67 AQEKLELTEKKASDAEGDVAALNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERG 126
+EK+ E+K D E + + R++ EE + R Q+++ +K+ E +K ++ ++
Sbjct: 491 QEEKMRDQEQKMWDQEERMWEQDERLREKEERM-REQKKMWQQEEKMREEKKTQEQEKKT 549
Query: 127 MKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAEERAEVS 186
+ M++EE+M +E +++E + + E + K +E K+ E ++ EE+ +
Sbjct: 550 WD--QEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQ 607
Query: 187 ELKCGDLEEELKNVTNNLKSLE------AASEKYSEKEDK---YEEEIKLLSDKLKEAET 237
E K + EE++ K E EK E+E+K EE+++ +K++E E
Sbjct: 608 EEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEE 667
Query: 238 RAEFAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTL 274
+ + E + + E+ + EEK+ + +E+ G + +
Sbjct: 668 KMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKM 704
Score = 71.6 bits (174), Expect = 7e-13
Identities = 50/237 (21%), Positives = 114/237 (48%), Gaps = 9/237 (3%)
Query: 2 EAIKKKMQMLKLDKENAIDRAEQAEADKKAAEDKCKQVEEELTHLQKKLKGTEDELDKYS 61
E ++++ +M + +++ ++ Q + K +++ + EE + +KK++ E+ + +
Sbjct: 521 ERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQE 580
Query: 62 EDLKDAQEKLELTEKKASDAEGDVAALNRRIQLVEEELDRAQERLATALQKLEEAEKAAD 121
E +++ +EK+ E+K + E + ++ EE++ +E K++E E+
Sbjct: 581 EKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEE-----DKMQEQEEMMW 635
Query: 122 ESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAEE 181
E E M+ E + + EEKM QE +++E + + + K E K+ E ++ EE
Sbjct: 636 EQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEE 695
Query: 182 RAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETR 238
+ E K EE++ + E+ EKE++ ++ + + ++L E E R
Sbjct: 696 KMRGQEEKMWGQEEKMWGQEEKM----WGQEEMREKEERIRDQKEKMQERLPEHEER 748
Score = 70.9 bits (172), Expect = 1e-12
Identities = 64/267 (23%), Positives = 125/267 (46%), Gaps = 27/267 (10%)
Query: 2 EAIKKKMQMLKLDKENAIDRAEQAEADKKAAEDKCKQVEEELTHLQKKLKGTEDELDKYS 61
E +KKK +L ++ + +E++E E K K + Q + ++E+ +
Sbjct: 183 EELKKKNA--ELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQE 240
Query: 62 EDLKDAQEKLELTEKKASDAEGDVAALNRRIQLVEEELDRAQERLATALQKLEEAEKAAD 121
E+L++ ++K+ E+K E + +++ EE++ R ++RL ++L E EK
Sbjct: 241 EELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEK--- 297
Query: 122 ESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAEE 181
+++++K+ QE Q++E + E + K E K+ E L E+
Sbjct: 298 ------------ELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEK 345
Query: 182 RAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAEF 241
+ E K D EE + L+ E E+ E+E +E+E K+ + E R
Sbjct: 346 QMREQEQKMRDQEERMWEQDERLREKE---ERMREQEKMWEQEEKM------QEEERIRE 396
Query: 242 AERTVAKLEKTIDDLEEKLAQAKEENV 268
E+ + + E+T+ + EEK+ Q +EEN+
Sbjct: 397 REKKMREEEETMREQEEKM-QKQEENM 422
Score = 67.0 bits (162), Expect = 2e-11
Identities = 62/250 (24%), Positives = 116/250 (46%), Gaps = 16/250 (6%)
Query: 16 ENAIDRAEQAEADKKAAEDKCKQVEEELTHLQKKLKGTEDELDKYSEDLKDAQEKLELTE 75
E ++ E+ KK + + K EE+ T Q++ K T D+ +K E+ E++ E
Sbjct: 514 ERLREKEERMREQKKMWQQEEKMREEKKT--QEQEKKTWDQEEKMREE-----ERMRERE 566
Query: 76 KKASDAEGDVAALNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAM 135
KK + E + ++Q EE++ +E++ +K++E E+ E E M E
Sbjct: 567 KKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQE---- 622
Query: 136 KDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAEERAEVSELKCGDLEE 195
+E+KM+ QE + E + +E + K E K+ E ++ EE+ + E K + EE
Sbjct: 623 -EEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEE 681
Query: 196 ELKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDD 255
+++ ++ E EK EE++ +K+ E E ER + EK
Sbjct: 682 KMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEK---- 737
Query: 256 LEEKLAQAKE 265
++E+L + +E
Sbjct: 738 MQERLPEHEE 747
Score = 65.1 bits (157), Expect = 7e-11
Identities = 60/278 (21%), Positives = 127/278 (45%), Gaps = 13/278 (4%)
Query: 2 EAIKKKMQMLKLDKENAIDRAEQAEADKKA--------AEDKCKQVEEELTHLQKKLKGT 53
E ++++ + + +E D+ E +KK ED+ + EE++ ++K+
Sbjct: 446 EKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQ 505
Query: 54 EDELDKYSEDLKDAQEKLELTEKKASDAEGDVAALNRRIQLVEEELDRAQERLATALQKL 113
E+ + + E L++ +E++ E+K + + ++ Q E++ +E++ +++
Sbjct: 506 EERMWEQDERLREKEERMR--EQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREE-ERM 562
Query: 114 EEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILE 173
E EK E E M+ E + + EEKM QE ++ E + +E + K E K+ E
Sbjct: 563 REREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQE 622
Query: 174 GE--LERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDK 231
E ++ EE E K + EE++ ++ E + EK EE+++ +K
Sbjct: 623 EEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEK 682
Query: 232 LKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEENVG 269
++ E + E + E+ + EEK+ +E+ G
Sbjct: 683 MQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWG 720
Score = 59.3 bits (142), Expect = 4e-09
Identities = 61/299 (20%), Positives = 145/299 (48%), Gaps = 25/299 (8%)
Query: 2 EAIKKKMQMLKLDKENAIDRAEQAEADKKAAEDKCKQVEEELTHL--QKKLKGTEDELDK 59
E + ++ + L+ + ++ E+ +K ++ K++ E+ L QKKL+ E+++ +
Sbjct: 255 EKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQE 314
Query: 60 YSEDL-------KDAQEKLELTEKKASDAEGDVAALNRRIQLVEEELDRAQERLATALQK 112
E + ++ +EK+ E++ + E + ++++ EE + ERL ++
Sbjct: 315 QEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEER 374
Query: 113 LEEAEKAADESER-----GMKVIENRAMKDEEKMEIQEMQL-KEAKHIAEEADRKYEE-- 164
+ E EK ++ E+ ++ E + ++EE M QE ++ K+ +++ E+ ++++++
Sbjct: 375 MREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQR 434
Query: 165 -VARKLVILEGE-LERAEERAEVSELKCGDLEE---ELKNVTNNLKSLEAASEKYSEKED 219
+K + E E ++ EE+ E K D EE + K + K E + + ++E
Sbjct: 435 LPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEK 494
Query: 220 KYEEEIKL--LSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQ 276
++E K+ +++ E + R E + + +K + EEK+ + K+ +T DQ
Sbjct: 495 MRDQEQKMWDQEERMWEQDERLREKEERMRE-QKKMWQQEEKMREEKKTQEQEKKTWDQ 552
Score = 54.7 bits (130), Expect = 9e-08
Identities = 38/194 (19%), Positives = 97/194 (50%), Gaps = 16/194 (8%)
Query: 4 IKKKMQMLKLDKENAIDRAEQAEADKKAA---EDKCKQVEEELTHLQKKL--KGTEDELD 58
++++ +M++ +E ++ E+ ++ E+K ++ EE++ ++K+ + ED++
Sbjct: 569 MREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQ 628
Query: 59 KYSEDLKDAQEKLELTEKKASDAEGDVAALNRRIQLVEEELDRAQERLATALQKLEEAEK 118
+ E + + +EK++ E+K + E + +++ EE++ +E++ +K++ E+
Sbjct: 629 EQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEE 688
Query: 119 AADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELER 178
E E M+ E + EEKM QE ++ + + E+ +R + + E+
Sbjct: 689 KMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEER-----------IRDQKEK 737
Query: 179 AEERAEVSELKCGD 192
+ER E +C +
Sbjct: 738 MQERLPEHEERCSE 751
Score = 36.2 bits (82), Expect = 0.034
Identities = 52/235 (22%), Positives = 89/235 (37%), Gaps = 46/235 (19%)
Query: 75 EKKASDAEGDVAALNRRIQLVEEE---LDRAQERLATALQKLEEAEKAADESERG-MKVI 130
EKKAS + AL R I+ + L + L TAL ++A + ++ G K +
Sbjct: 72 EKKASHQHQE--ALRREIEAQDHTIRILTCQKTELETALYYSQDAARKFEDGNLGESKDL 129
Query: 131 ENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGEL-------------- 176
R + L ++ADR EE+ ++ L EL
Sbjct: 130 AGRLHHSWHFAGELQRALSAVSTWHKKADRYIEELTKERDALSLELYRNTITNEELKKKN 189
Query: 177 ------------ERAEERAEVSELK--------------CGDLEEELKNVTNNLKSLEAA 210
E++E + V ELK L+EE+ L+ E
Sbjct: 190 AELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKK 249
Query: 211 SEKYSEKEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKE 265
K EK + EE ++ K++E E + E+ + + EK + + E++L + K+
Sbjct: 250 IRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKK 304
Score = 32.3 bits (72), Expect = 0.48
Identities = 21/115 (18%), Positives = 55/115 (47%), Gaps = 4/115 (3%)
Query: 1 MEAIKKKMQMLKLDKENAIDRAEQAEADKKAAEDKCKQVEEELTHLQKKLKGTEDELDKY 60
M+ ++KM + ++ + E + E+K ++ EE++ ++K++ E+++
Sbjct: 641 MQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQ 700
Query: 61 SEDLKDAQEKLELTEKKASDAEGDVAALNRRIQLVEEELDRAQERLATALQKLEE 115
E + +EK+ E+K E + + + + ++ ++ QERL ++ E
Sbjct: 701 EEKMWGQEEKMWGQEEKMWGQE----EMREKEERIRDQKEKMQERLPEHEERCSE 751
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 80.5 bits (197), Expect = 2e-15
Identities = 64/276 (23%), Positives = 134/276 (48%), Gaps = 14/276 (5%)
Query: 2 EAIKKKMQMLKLDKENAIDRAEQAEADKKAAEDKCKQVEEELTHLQKKLKGTEDELDKYS 61
E +++ +M+ +E + E+ +K E + K+ EEE Q+K + E ++ +
Sbjct: 363 EKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQE 422
Query: 62 EDLKDAQEKLELTEKKASDAEGDVAALNRRIQLVEEELDRAQERLATALQKLEEAEKAAD 121
E +++ +EK+ EKK E + + + ++ EEE + QE + +K+ E E+
Sbjct: 423 EKIREQEEKIREQEKKMWRQEEKI---HEQEKIREEEKRQEQEEMWRQEEKIREQEEIWR 479
Query: 122 ESER-----GMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGEL 176
+ E+ ++ E + + EEKM QE +++E + + K E K+ E ++
Sbjct: 480 QKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKI 539
Query: 177 ERAEERAEVSELKCGDLEEELKN---VTNNLKSLEAASEKYSEKEDKY---EEEIKLLSD 230
EE + E K G+ EE+++ + + + EK E+++K EE+I +
Sbjct: 540 REQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEE 599
Query: 231 KLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEE 266
K++E E + E + + E+ + + EEK+ + +E+
Sbjct: 600 KIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEK 635
Score = 74.7 bits (182), Expect = 9e-14
Identities = 60/273 (21%), Positives = 140/273 (51%), Gaps = 15/273 (5%)
Query: 2 EAIKKKMQMLKLDKENAIDRAEQAEADKKAAEDKCKQVEEELTHLQKKLKGTEDELDKYS 61
E I+++ + ++ ++E + R E+ +K E+K ++ EE + ++K++ E+ + +
Sbjct: 321 EKIREQEEKIR-EQEEKMRRQEEMMWEK---EEKMRRQEEMMWEKEEKMRRLEEMMWEKE 376
Query: 62 EDLKDAQEKL----ELTEKKASDAEGDVAALNRRIQLVEEELDRAQERLATALQKLEEAE 117
E +++ +EK+ ++ E++ E + + Q E ++ R +E++ +K+ E E
Sbjct: 377 EKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQE 436
Query: 118 KAADESERGM----KVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILE 173
K E + K+ E +++E+M QE +++E + I + ++ +E+ K+ E
Sbjct: 437 KKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQ--EKIRKQE 494
Query: 174 GELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLK 233
++ R EE+ E K + EE++ ++ E + EK + EE ++ +K+
Sbjct: 495 EKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMG 554
Query: 234 EAETRAEFAERTVAKLEKTIDDLEEKLAQAKEE 266
E E + + E+ + + E+ I + EEK+ + KE+
Sbjct: 555 EQEEKMQEQEK-MRRQEEKIREQEEKIREQKEK 586
Score = 73.6 bits (179), Expect = 2e-13
Identities = 59/264 (22%), Positives = 130/264 (49%), Gaps = 24/264 (9%)
Query: 2 EAIKKKMQMLKLDKENAIDRAEQAEADKKAAEDKCKQVEEELTHLQKKLKGTEDELDKYS 61
E I+++ + ++ ++ + E+ +K E++ +Q +EE+ ++K++ ++E+ +
Sbjct: 423 EKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIR-EQEEIWRQK 481
Query: 62 EDLKDAQEKLELTEKKASDAEGDVAALNRRIQLVEEELDRAQERLATALQKLEEAEKAAD 121
E + + QEK+ E+K E + +I+ EE++ R +E++ +K+ E E+
Sbjct: 482 EKMHE-QEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIR 540
Query: 122 ESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAEE 181
E E M+ E + + EEKM+ QE ++ + I E+ ++ E+ +E
Sbjct: 541 EQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQ---------------KE 585
Query: 182 RAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAEF 241
+ E K + EE+++ ++ E EK E+E+K E+ +K++E E +
Sbjct: 586 KIREQEEKIWEQEEKIREQEEMMQEQE---EKMWEQEEKMCEQ----EEKMQEQEEKMRR 638
Query: 242 AERTVAKLEKTIDDLEEKLAQAKE 265
E + + E + EEK+ + +E
Sbjct: 639 QEEKMWEQEVRLRQQEEKMQEHQE 662
Score = 73.2 bits (178), Expect = 2e-13
Identities = 56/272 (20%), Positives = 135/272 (49%), Gaps = 13/272 (4%)
Query: 1 MEAIKKKMQMLKLDKENAIDRAEQAEADKK-AAEDKCKQVEEELTHLQKKLKGTEDELDK 59
++++ K+Q ++++ +R Q + +K E+K ++ EE++ ++K++ E+++ +
Sbjct: 274 LQSVSAKLQA-QVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIRE 332
Query: 60 YSEDLKDAQEKLELTEKKASDAEGDVAALNRRIQLVEEELDRAQERLATALQKLEEAEKA 119
E ++ +E + E+K E + +++ +EE + +E++ +K+ E EK
Sbjct: 333 QEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKI 392
Query: 120 ADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERA 179
++ E+ E ++++EK + QE ++ + E + K E +K+ E E+
Sbjct: 393 REQEEKRQ---EEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQE---EKI 446
Query: 180 EERAEVSELKCGDLEEELKNVTNNLKSLE---AASEKYSEKED--KYEEEIKLLSDKLKE 234
E+ ++ E + +EE+ ++ E EK E+E K EE++ +K+ +
Sbjct: 447 HEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHD 506
Query: 235 AETRAEFAERTVAKLEKTIDDLEEKLAQAKEE 266
E + E + + E+ I + EEK+ + +E+
Sbjct: 507 QEEKIREQEEKMWRQEEKIREQEEKIREQEEK 538
Score = 65.9 bits (159), Expect = 4e-11
Identities = 63/247 (25%), Positives = 121/247 (48%), Gaps = 35/247 (14%)
Query: 37 KQVEEELTHLQKKLKGTEDELDKYSEDLKDAQEKLE----LTEKKASDAEGD-----VAA 87
++++E+ LQ+KL+ E E + ++K+ + KLE L ++ AE D + +
Sbjct: 217 EELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQS 276
Query: 88 LNRRIQLVEEELD-------RAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEK 140
++ ++Q EE + + +E++ +K++E E+ E E ++ E + + EEK
Sbjct: 277 VSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEK 336
Query: 141 MEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAEERAEVSELKCGDLEEELKNV 200
M QE + E EE R+ EE+ + E ++ R EE E K +LEE++
Sbjct: 337 MRRQEEMMWE----KEEKMRRQEEMMWE---KEEKMRRLEEMMWEKEEKIRELEEKMHE- 388
Query: 201 TNNLKSLEAASEKYSEKEDKYEEEIKLL-SDKLKEAETRAEFAERTVAKLEKTIDDLEEK 259
EK E+E+K +EE K+ +K +E E + E + + E+ I + E+K
Sbjct: 389 ----------QEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKK 438
Query: 260 LAQAKEE 266
+ + +E+
Sbjct: 439 MWRQEEK 445
Score = 62.0 bits (149), Expect = 6e-10
Identities = 61/259 (23%), Positives = 117/259 (45%), Gaps = 9/259 (3%)
Query: 7 KMQMLKLDKENAIDRAEQAEADKKAAEDKCKQVEEELTHLQKKLKGTED----ELDKYSE 62
K + KL ++ + +E++E E K K +L Q++L+ D EL S
Sbjct: 220 KEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSA 279
Query: 63 DLKDAQEKLELTEKKASDAEGDVAALNRRIQLVEEELDRAQERLATALQKLEEAEKAADE 122
L+ E+ EL + E + +IQ EE++ +E++ +K+ E E+
Sbjct: 280 KLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRR 339
Query: 123 SERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAEER 182
E M E + + EE M +E +++ + + E + K E+ K+ E E+ E+R
Sbjct: 340 QEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKR 399
Query: 183 AEVSELKCGDLEEELK-NVTNNLKSLEAASEKYSEKEDKY--EEEIKLLSDKLKEAETRA 239
E +++ + +E + + + + EK E+E K +EE +K++E E R
Sbjct: 400 QEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQ 459
Query: 240 EFAERTVAKLEKTIDDLEE 258
E + + + E+ I + EE
Sbjct: 460 E--QEEMWRQEEKIREQEE 476
Score = 62.0 bits (149), Expect = 6e-10
Identities = 66/275 (24%), Positives = 125/275 (45%), Gaps = 10/275 (3%)
Query: 1 MEAIKKKMQMLKLDKENAIDRAEQAEADKKAAEDKCK-QVEEELTHLQKKLKGTEDE-LD 58
++ +K+K++ KL +AE K+ K Q + E L +L ++E +
Sbjct: 244 VKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMW 303
Query: 59 KYSEDLKDAQEKLELTEKKASDAEGDVAALNRRIQLVEEELDRAQERLATALQKLEEAEK 118
+ E +++ +EK++ E+K + E + +++ EE + +E++ + + E E+
Sbjct: 304 RQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEE 363
Query: 119 AADESERGMKVIENRAMKDEEKMEIQE-MQLKEAKHIAEEADR---KYEEVARKLVILEG 174
E M E + + EEKM QE ++ +E K EE R K +E K+ E
Sbjct: 364 KMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEE 423
Query: 175 ELERAEERAEVSELKCGDLEE---ELKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDK 231
++ EE+ E K EE E + + K E E++ + +EEI +K
Sbjct: 424 KIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEK 483
Query: 232 LKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEE 266
+ E E + E V + E+ + D EEK+ + +E+
Sbjct: 484 MHEQE-KIRKQEEKVWRQEEKMHDQEEKIREQEEK 517
Score = 53.9 bits (128), Expect = 2e-07
Identities = 33/144 (22%), Positives = 72/144 (50%), Gaps = 1/144 (0%)
Query: 20 DRAEQAEADKKAAEDKCKQVEEELTHLQKKLKGTEDELDKYSEDLKDAQEKLELTEKKAS 79
++ + E + E+K ++ EE + ++K+ G ++E + E ++ +EK+ E+K
Sbjct: 523 EKIREQEEKIREQEEKIREQEEMMQEQEEKM-GEQEEKMQEQEKMRRQEEKIREQEEKIR 581
Query: 80 DAEGDVAALNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEE 139
+ + + +I EE++ +E + +K+ E E+ E E M+ E + + EE
Sbjct: 582 EQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEE 641
Query: 140 KMEIQEMQLKEAKHIAEEADRKYE 163
KM QE++L++ + +E E
Sbjct: 642 KMWEQEVRLRQQEEKMQEHQEHLE 665
Score = 36.2 bits (82), Expect = 0.034
Identities = 24/109 (22%), Positives = 56/109 (51%), Gaps = 11/109 (10%)
Query: 2 EAIKKKMQMLKLDKENAIDRAEQAEADKKAAEDKCKQVEEELTHLQKKLKGTEDELDKYS 61
E I+++ + ++ KE ++ E+ E+K ++ EE + ++K+ E+++ +
Sbjct: 571 EKIREQEEKIREQKEKIREQEEKIWEQ----EEKIREQEEMMQEQEEKMWEQEEKMCEQE 626
Query: 62 EDLKDAQEKLELTEKKASDAEGDVAALNRRIQLVEEELDRAQERLATAL 110
E +++ +EK+ E+K + E R++ EE++ QE L A+
Sbjct: 627 EKMQEQEEKMRRQEEKMWEQEV-------RLRQQEEKMQEHQEHLEAAI 668
Score = 35.4 bits (80), Expect = 0.057
Identities = 33/161 (20%), Positives = 72/161 (44%), Gaps = 23/161 (14%)
Query: 114 EEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILE 173
E+ +KA+ + + ++ + + Q+ +L+ A + ++ A ++ E AR L+
Sbjct: 108 EDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLI--- 164
Query: 174 GELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKY----------EE 223
R S G+LE+ L V K + E+ +++ D +E
Sbjct: 165 -------SRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDE 217
Query: 224 EIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAK 264
E+K + KL+E + + E ++++ + +L+ KL +AK
Sbjct: 218 ELKEKNAKLQE---KLQLVESEKSEIQLNVKELKRKLERAK 255
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 80.5 bits (197), Expect = 2e-15
Identities = 70/271 (25%), Positives = 127/271 (46%), Gaps = 14/271 (5%)
Query: 2 EAIK--KKMQMLKLDKENAID--RAEQAE--ADKKAAEDKCKQVEEELTHLQKKLKGTED 55
EAIK +K+Q D +D RA + E A K E K K +E E+ LQ++L E
Sbjct: 1635 EAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAER 1694
Query: 56 ELDKYSEDLKDAQEKLELTEKKASDAEGDVAALNRRIQLVEEELDRAQERLATALQKLEE 115
+ ++ + +++ + K + A + L RI +EEEL+ Q +L++
Sbjct: 1695 AKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKK 1754
Query: 116 AEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEAD----RKYEE----VAR 167
A D+ + + + A K+E + E Q KE K +E + KY+ +
Sbjct: 1755 ANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYKASITALEA 1814
Query: 168 KLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEIKL 227
K+ LE +L+ + + + + E++LK+V + +E+Y ++ DK +K
Sbjct: 1815 KIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQ 1874
Query: 228 LSDKLKEAETRAEFAERTVAKLEKTIDDLEE 258
L +L+EAE A+ A + KL++ ++D E
Sbjct: 1875 LKRQLEEAEEEAQRANASRRKLQRELEDATE 1905
Score = 74.3 bits (181), Expect = 1e-13
Identities = 73/316 (23%), Positives = 136/316 (43%), Gaps = 41/316 (12%)
Query: 7 KMQMLKLDKE--NAIDRAEQAEADKKAAEDKCKQVEEELTHLQKKLKGTEDELDKYSEDL 64
KMQ+ K ++E A+ R E+ A K A K +++E +++ LQ+ L+ +K +
Sbjct: 1075 KMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQK 1134
Query: 65 KDAQEKLELTEKKASDAEGDVAALNR-------------------------RIQLVEEEL 99
+D E+LE + + D AA +IQ + ++
Sbjct: 1135 RDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKH 1194
Query: 100 DRAQERLATALQKLE------EAEKAADESERG-----MKVIENRAMKDEEKMEIQEMQL 148
+A E LA L++ + E K E+ERG +KV+ E K + E QL
Sbjct: 1195 SQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQL 1254
Query: 149 KEAKHIAEEADRKYEEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLE 208
+E + E +R E+A K+ L+ EL+ S+ K L ++ + + L+ +
Sbjct: 1255 QELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQ 1314
Query: 209 AASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAK---E 265
++ + ++ ++K + D+ + E E LEK I L ++A K E
Sbjct: 1315 ELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKME 1374
Query: 266 ENVGLHQTLDQTLNEL 281
++VG +T ++ +L
Sbjct: 1375 DSVGCLETAEEVKRKL 1390
Score = 69.3 bits (168), Expect = 4e-12
Identities = 70/290 (24%), Positives = 132/290 (45%), Gaps = 21/290 (7%)
Query: 1 MEAIKKKMQMLKLDKENAIDRAEQAEADKKAAEDKCKQVEEELTHLQKKLKGTEDELDKY 60
+E + Q L+L+K EA K E++ +E++ L K+ K ED + ++
Sbjct: 952 LEEEESARQKLQLEKVT-------TEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEF 1004
Query: 61 SEDLKDAQEKLELTEKKASDAEGDVAALNRRIQLVE---EELDRAQERLATALQKLEE-- 115
+ +L + +EK + K + E + L R++ E +EL++ + +L L +
Sbjct: 1005 TTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQI 1064
Query: 116 AEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGE 175
AE A +E M++ K EE+++ +++E A +K E+ ++ L+ +
Sbjct: 1065 AELQAQIAELKMQL-----AKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQED 1119
Query: 176 LERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKL-KE 234
LE +E + DL EEL+ + L+ ++ E K E+E+ +L L +E
Sbjct: 1120 LESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEE 1179
Query: 235 AETRAEFAERTVAKLEKTIDDLEEKLAQAKEENVGLH---QTLDQTLNEL 281
A+T + K + +++L E+L Q K L QTL+ EL
Sbjct: 1180 AKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGEL 1229
Score = 68.6 bits (166), Expect = 6e-12
Identities = 56/247 (22%), Positives = 112/247 (45%), Gaps = 7/247 (2%)
Query: 42 ELTHLQKKLKGTEDELDKYSEDLKDAQEKLELTEKKASDAEGDVAALNRRIQLVEEELDR 101
+++ ++++ E+EL K E A+ +L E S + L ++Q E
Sbjct: 839 QVSRQEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAE 898
Query: 102 AQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRK 161
A+E A K +E E+ + E ++ E R + + + + ++E + EE +
Sbjct: 899 AEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESA 958
Query: 162 YEEVARKLVILEGELERAEERAEVSE---LKCGD----LEEELKNVTNNLKSLEAASEKY 214
+++ + V E +L++ EE + E K LE+ + T NL E S+
Sbjct: 959 RQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSL 1018
Query: 215 SEKEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTL 274
++ ++K+E I L ++L+ E + + E+T KLE DL +++A+ + + L L
Sbjct: 1019 AKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQL 1078
Query: 275 DQTLNEL 281
+ EL
Sbjct: 1079 AKKEEEL 1085
Score = 63.5 bits (153), Expect = 2e-10
Identities = 62/293 (21%), Positives = 128/293 (43%), Gaps = 14/293 (4%)
Query: 2 EAIKKKMQMLKLDKENAIDRAEQAEADKKAAEDKCKQVEEELTHLQKKLKGTEDELDKYS 61
E K+ Q + + K+ + A+ EA + K Q EEL ++ K + L+K
Sbjct: 1160 ELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAK 1219
Query: 62 EDLKDAQEKLELTEKKASDAEGDVAALNRRIQLVEEELD---RAQERLATAL-QKLEEAE 117
+ L++ + +L K +GD ++++ +EL ER+ T L K+ + +
Sbjct: 1220 QTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQ 1279
Query: 118 KAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGE-- 175
D + ++++ K + E QL++ + + +E +R+ ++ KL +E E
Sbjct: 1280 VELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKN 1339
Query: 176 -----LERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSD 230
LE EE E + L ++ ++ ++ E E + K +++++ LS
Sbjct: 1340 SFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQ 1399
Query: 231 KLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEENVGL---HQTLDQTLNE 280
+ +E + E+T +L++ +DDL L ++ L + DQ L E
Sbjct: 1400 RHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAE 1452
Score = 63.2 bits (152), Expect = 3e-10
Identities = 66/279 (23%), Positives = 124/279 (44%), Gaps = 30/279 (10%)
Query: 4 IKKKMQMLKLDKENAID-RAEQAEADKKAAEDKCKQVEEELTHLQKKLKGTEDELDKYSE 62
++ +Q +K E + R EQ+E KK + +++E EL +K+ K
Sbjct: 1558 LEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEM 1617
Query: 63 DLKDAQEKLELTEKKASDAEGDVAALNRRIQLVEEELDRAQERLATALQKLEEAEKAADE 122
DLKD + ++ K +A + L +++ ELD + EE A E
Sbjct: 1618 DLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRA-------SREEILAQAKE 1670
Query: 123 SERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAEER 182
+E+ +K +E E +++QE +L A+ +A ++ +E+A ++ G+ A E
Sbjct: 1671 NEKKLKSME------AEMIQLQE-ELAAAERAKRQAQQERDELADEIANSSGKGALALEE 1723
Query: 183 AEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEIKL--------------L 228
E + LEEEL+ N + + +K + + D+ ++ L L
Sbjct: 1724 KRRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQL 1783
Query: 229 SDKLKEAETRAEFAERTV-AKLEKTIDDLEEKLAQAKEE 266
+ KE + + + E TV +K + +I LE K+AQ +E+
Sbjct: 1784 ERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQ 1822
Score = 62.4 bits (150), Expect = 4e-10
Identities = 72/320 (22%), Positives = 143/320 (44%), Gaps = 42/320 (13%)
Query: 4 IKKKMQMLKLDKENAIDRAE----QAEADKKAAEDKCKQVEEELTHLQKKLKGTEDELDK 59
+K K + + D E + R E + E ++ E + +++ LQ ++ + +L K
Sbjct: 1021 LKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAK 1080
Query: 60 YSEDLKDAQEKLE-------LTEKKASDAEGDVAALNRRIQLVEEELDRAQ--------- 103
E+L+ A ++E + KK + E ++ L ++ ++A+
Sbjct: 1081 KEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEE 1140
Query: 104 -ERLATALQKLEEAEKAADE--SERGMKV-IENRAMKDEEK---MEIQEMQLKEAKHIAE 156
E L T L+ ++ A E S+R +V I + +++E K +IQEM+ K ++ + E
Sbjct: 1141 LEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAV-E 1199
Query: 157 EADRKYEEVARKLVILEGELERAE-ERAEV-SELKC-----GDLEEELKNVTNNLKSL-- 207
E + E+ R LE + E ER E+ +E+K GD E + K V L+ L
Sbjct: 1200 ELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQV 1259
Query: 208 -----EAASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQ 262
E + ++K K + E+ ++ L ++++++ + + LE + D +E L +
Sbjct: 1260 KFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQE 1319
Query: 263 AKEENVGLHQTLDQTLNELN 282
+ + L L Q +E N
Sbjct: 1320 ENRQKLSLSTKLKQVEDEKN 1339
Score = 60.1 bits (144), Expect = 2e-09
Identities = 55/249 (22%), Positives = 118/249 (47%), Gaps = 24/249 (9%)
Query: 24 QAEADKKAAEDKCKQVEEELTHLQKKLKGTEDELDKYSEDLKDAQEKLELTEKKASDAEG 83
Q + +A + C + EE L+ +L + EL++ DL + ++E E++ +
Sbjct: 884 QLQEQLQAETELCAEAEE----LRARLTAKKQELEEICHDL---EARVEEEEERCQHLQA 936
Query: 84 DVAALNRRIQLVEEELDRAQERLATALQKLEEAEKAADES-----ERGMKVIENRAMKDE 138
+ + + IQ +EE+L+ + +A QKL + EK E+ E ++E++ K
Sbjct: 937 EKKKMQQNIQELEEQLEEEE----SARQKL-QLEKVTTEAKLKKLEEEQIILEDQNCKLA 991
Query: 139 EKMEIQEMQLKEAKHIAEEADRKYEEVAR-------KLVILEGELERAEERAEVSELKCG 191
++ ++ E ++ E E + K + +A+ + LE L R E++ + E
Sbjct: 992 KEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRR 1051
Query: 192 DLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEK 251
LE + ++++ + L+A + + K EEE++ +++E + A + + +LE
Sbjct: 1052 KLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELES 1111
Query: 252 TIDDLEEKL 260
I +L+E L
Sbjct: 1112 QISELQEDL 1120
Score = 59.7 bits (143), Expect = 3e-09
Identities = 60/264 (22%), Positives = 119/264 (45%), Gaps = 22/264 (8%)
Query: 33 EDKCKQVEEELTHLQ---KKLKGTEDELDKYSEDLKDAQEKLEL----TEKKASDAEGDV 85
E + ++ EE HLQ KK++ EL++ E+ + A++KL+L TE K E +
Sbjct: 921 EARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQ 980
Query: 86 AALNRRIQLVEEELDRAQERLATALQKLEEAE-------KAADESERGMKVIENRAMKDE 138
L + + +E ++R+A L E E K ++ E + +E R ++E
Sbjct: 981 IILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREE 1040
Query: 139 EKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAEERAEVSELKCGDLEEELK 198
++ + E ++ + + + + E+ ++ L+ +L + EE + + + +EEE
Sbjct: 1041 KQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALAR---VEEEAA 1097
Query: 199 NVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDD--L 256
LK + + SE ++ E E + K+ E E +LE T+D
Sbjct: 1098 QKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAA 1157
Query: 257 EEKLAQAKEENVGLHQTLDQTLNE 280
+++L +E+ V + L +TL E
Sbjct: 1158 QQELRSKREQEVNI---LKKTLEE 1178
Score = 59.7 bits (143), Expect = 3e-09
Identities = 61/299 (20%), Positives = 136/299 (45%), Gaps = 36/299 (12%)
Query: 2 EAIKKKMQMLKLDKENAIDRAEQAEADKKAAEDKCKQVEEELTHLQKKLKGTEDELDKYS 61
EA+++K ++ +L+K+ R E + + +D K V E L+K + E ++++
Sbjct: 1487 EAMEQKAELERLNKQF---RTEMEDL-MSSKDDVGKSVHE----LEKSKRALEQQVEEMK 1538
Query: 62 EDLKDAQEKLELTEKKASDAEGDVAALN----RRIQLVEEELDRAQERLATALQKLEEAE 117
L++ +++L+ TE E ++ A+ R +Q +E+ + +++L ++++E AE
Sbjct: 1539 TQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREME-AE 1597
Query: 118 KAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGEL- 176
+ +R M V + + EM LK+ + + A++ +E ++L L+ ++
Sbjct: 1598 LEDERKQRSMAVAARKKL---------EMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMK 1648
Query: 177 -------------ERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEE 223
E +A+ +E K +E E+ + L + E A + ++ D+ +
Sbjct: 1649 DCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELAD 1708
Query: 224 EIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQTLNELN 282
EI S K A E +A+LE+ +++ + + + +DQ +LN
Sbjct: 1709 EIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLN 1767
Score = 56.2 bits (134), Expect = 3e-08
Identities = 70/307 (22%), Positives = 129/307 (42%), Gaps = 42/307 (13%)
Query: 4 IKKKMQMLKLDKENAIDRAEQAEADKKAAEDKCKQVEEELTHLQKKLKGTE-------DE 56
++K Q L+ ++ + + K +E K K+VE +L LQ K E D+
Sbjct: 1215 LEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADK 1274
Query: 57 LDKYSEDLKDAQEKLELTEKKASDAEGDVAALNRRIQLVEE---ELDRAQERLATAL--- 110
+ K +L + L ++ K+S D +AL ++Q +E E +R + L+T L
Sbjct: 1275 VTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQV 1334
Query: 111 --------QKLEEAEKAADESERGMKVIENRAMKDEEKME--------IQEMQLKEAKHI 154
++LEE E+A E+ + + + ++KME +E++ K K +
Sbjct: 1335 EDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDL 1394
Query: 155 A------EEADRKYEEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLE 208
EE Y+++ + L+ EL+ + +LE++ K L +
Sbjct: 1395 EGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEK 1454
Query: 209 AASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEENV 268
S KY+E+ D+ E E + E ET+A R + + + +LE Q + E
Sbjct: 1455 TISAKYAEERDRAEAEAR-------EKETKALSLARALEEAMEQKAELERLNKQFRTEME 1507
Query: 269 GLHQTLD 275
L + D
Sbjct: 1508 DLMSSKD 1514
Score = 56.2 bits (134), Expect = 3e-08
Identities = 56/293 (19%), Positives = 123/293 (41%), Gaps = 29/293 (9%)
Query: 7 KMQMLKLDKENAIDRAEQAEA-------DKKAAEDKCKQVEEELTH-------LQKKLKG 52
K+ L+++ +N Q+++ D A E + + +E L L KLK
Sbjct: 1274 KVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQ 1333
Query: 53 TEDELDKYSEDLKDAQEKLELTEKKASDAEGDVAALNRR-------IQLVEEELDRAQER 105
EDE + + E L++ +E EK+ + VA + ++ ++ EE + Q+
Sbjct: 1334 VEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKD 1393
Query: 106 LATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEV 165
L Q+ EE A D+ E+ + R ++ + + + +++ E+ +K++++
Sbjct: 1394 LEGLSQRHEEKVAAYDKLEK----TKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQL 1449
Query: 166 ARKLVILEG----ELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKY 221
+ + E +RAE A E K L L+ LE ++++ + +
Sbjct: 1450 LAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDL 1509
Query: 222 EEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTL 274
+ + E E E+ V +++ +++LE++L ++ + L L
Sbjct: 1510 MSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNL 1562
Score = 55.8 bits (133), Expect = 4e-08
Identities = 53/300 (17%), Positives = 139/300 (46%), Gaps = 19/300 (6%)
Query: 1 MEAIKKKMQMLKLDKENAIDRAEQAEADKKAAEDKCKQVEEELTHLQKKLKGTEDELDKY 60
+E K ++Q D +D Q+ + + + K Q+ E + K D +
Sbjct: 1411 LEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAE 1470
Query: 61 SEDLKDAQEKLELTEKKASDAEGDVAALNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
+ + + L ++A + + ++ LN++ + E+L +++ + ++ +LE++++A
Sbjct: 1471 AREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRAL 1530
Query: 121 DESERGMKV----IENRAMKDEE-----KMEIQEMQLKEAKHIA---EEADRKYEEVARK 168
++ MK +E+ E+ ++ +Q M+ + + + E+++ K +++ R+
Sbjct: 1531 EQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQ 1590
Query: 169 LVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEIKLL 228
+ +E ELE ++ ++ LE +LK++ ++ S ++ ++ K + ++K
Sbjct: 1591 VREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDC 1650
Query: 229 SDKL-------KEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQTLNEL 281
+L +E +A+ E+ + +E + L+E+LA A+ Q D+ +E+
Sbjct: 1651 MRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEI 1710
Score = 55.8 bits (133), Expect = 4e-08
Identities = 49/228 (21%), Positives = 99/228 (43%), Gaps = 22/228 (9%)
Query: 17 NAIDRAEQAEADKKAAEDKCKQVEEELTHLQ-------KKLKGTEDELDKYSEDLKDAQE 69
N+ + A +K+ E + Q+EEEL Q +LK ++D+ + DL +
Sbjct: 1712 NSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLERS 1771
Query: 70 KLELTEKKASDAEGDVAALNRRIQLVEEELDRAQERLATALQ-KLEEAEKAADESERGMK 128
+ E E L ++Q +E + + TAL+ K+ + E+ D + +
Sbjct: 1772 HAQKNENARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQ 1831
Query: 129 VIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAEERAEVSEL 188
+ + E+K++ +Q+ + + AE+ + ++ + +L L+ +LE AEE A+ +
Sbjct: 1832 AACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANA 1891
Query: 189 KCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAE 236
L+ EL++ T E D E+ L +KL+ +
Sbjct: 1892 SRRKLQRELEDAT--------------ETADAMNREVSSLKNKLRRGD 1925
Score = 49.7 bits (117), Expect = 3e-06
Identities = 40/178 (22%), Positives = 80/178 (44%), Gaps = 12/178 (6%)
Query: 23 EQAEADKKAAEDKCKQVE--------EELTHLQKKLKGTEDELDKYSEDLKDAQEKLELT 74
+Q E K + K +++E +T L+ K+ E++LD +++ + A +++ T
Sbjct: 1781 QQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAACKQVRRT 1840
Query: 75 EKKASDAEGDVAALNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRA 134
EKK D V R + +++ D+A RL ++LEEAE+ A + + ++
Sbjct: 1841 EKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQREL 1900
Query: 135 MKDEEKMEIQEMQLKEAKHIAEEADRKY---EEVARKLVILEGELERAEERAEVSELK 189
E + ++ K+ D + +ARK +G E + +A+ +E K
Sbjct: 1901 EDATETADAMNREVSSLKNKLRRGDLPFVVPRRMARK-GAGDGSDEEVDGKADGAEAK 1957
Score = 28.9 bits (63), Expect = 5.4
Identities = 16/75 (21%), Positives = 36/75 (48%)
Query: 5 KKKMQMLKLDKENAIDRAEQAEADKKAAEDKCKQVEEELTHLQKKLKGTEDELDKYSEDL 64
+KK++ + L ++ AEQ + A + KQ++ +L +++ + K +L
Sbjct: 1841 EKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQREL 1900
Query: 65 KDAQEKLELTEKKAS 79
+DA E + ++ S
Sbjct: 1901 EDATETADAMNREVS 1915
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 80.5 bits (197), Expect = 2e-15
Identities = 61/246 (24%), Positives = 118/246 (47%), Gaps = 19/246 (7%)
Query: 37 KQVEEELTHLQKKLKGTEDELDKYSEDLKDAQEKLELTEKKASDAEGDVAA--LNRRIQL 94
++++E+ LQ+KL+ E E + ++KD + KLE + + V A L + +Q
Sbjct: 214 EELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQS 273
Query: 95 VEEEL--------------DRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEK 140
V +L + +E++ +K++E E+ E E ++ E + + EEK
Sbjct: 274 VSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEK 333
Query: 141 MEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAEERAEVSELKCGDLEEELKNV 200
M QE +++E + + K E K+ E ++ R EE+ + K + EEE+
Sbjct: 334 MHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQ 393
Query: 201 TNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKL 260
++ E EK EK + E++++ +K++E E E + +LE+ + D EEKL
Sbjct: 394 EEKIREQE---EKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKL 450
Query: 261 AQAKEE 266
+ +E+
Sbjct: 451 REVEEK 456
Score = 79.0 bits (193), Expect = 5e-15
Identities = 65/293 (22%), Positives = 137/293 (46%), Gaps = 31/293 (10%)
Query: 1 MEAIKKKMQMLKLDKENAIDRAEQAEADKKAAEDKCKQVEEELTHLQKKLKGTEDELDKY 60
++++ K+Q + E +Q E E+K ++ EE++ + K++ E+++ +
Sbjct: 271 LQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQ 330
Query: 61 SEDLKDAQEKLELTEKKASDAEGDVAALNRRIQLVEEELDRAQERLATALQKLEE----- 115
E + + +EK+ E K E + +I+ EE++ R +E++ +K++E
Sbjct: 331 EEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEM 390
Query: 116 ---AEKAADE----------SERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKY 162
EK ++ E+ M+ + + + EE+M QE +++E + + ++ + K
Sbjct: 391 WRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKL 450
Query: 163 EEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLE----------AASE 212
EV K+ E +++ EE+ + E K + EE+ LK E E
Sbjct: 451 REVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEE 510
Query: 213 KYSEKEDK---YEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQ 262
K E+E+K EE+++ +K++E E R E + + E + +LEE+L +
Sbjct: 511 KMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGK 563
Score = 74.7 bits (182), Expect = 9e-14
Identities = 59/271 (21%), Positives = 130/271 (47%), Gaps = 9/271 (3%)
Query: 2 EAIKKKMQMLKLDKENAIDRAEQAEADKKAAEDKCKQVEEELTHLQKKLKGTEDELDKYS 61
+ + K++Q + + ++ E + E+K + EE++ ++K+ E ++ +
Sbjct: 265 DRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQE 324
Query: 62 EDLKDAQEKLELTEKKASDAEGDVAALNRRIQLVEEELDRAQERLATALQKLEEAEKAAD 121
E + +EK+ E+K + E + +I+ EE++ +E++ +K+ E ++
Sbjct: 325 EKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQ 384
Query: 122 ESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAEE 181
E E M E + + EEK QE ++ K + E+ D K E ++ E ++ EE
Sbjct: 385 EQEEEMWRQEEKIREQEEKR--QEKMWRQEKKMREQ-DEKIREQEEEMWRQEEKIRELEE 441
Query: 182 RAEVSELKCGDLEEELKNVTNNL----KSLEAASEKYSEKEDKYEEEIKLL--SDKLKEA 235
+ E K ++EE+++ + + ++ EK E+E+K + KLL +K+ E
Sbjct: 442 MMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQ 501
Query: 236 ETRAEFAERTVAKLEKTIDDLEEKLAQAKEE 266
E + E + + E+ + + EEK+ + +E+
Sbjct: 502 EEKMWRQEEKMWEQEEKMQEQEEKMQRQEEK 532
Score = 72.8 bits (177), Expect = 3e-13
Identities = 61/276 (22%), Positives = 133/276 (48%), Gaps = 11/276 (3%)
Query: 1 MEAIKKKMQMLKLDKENAIDRAEQAEADKKAAEDKCKQVEEELTHLQKKLKGTEDELDKY 60
+E+ K ++Q+ D + ++RA Q ++ + + ++ +EL + KL+ +E + +
Sbjct: 230 VESEKSEIQLNVKDLKRKLERA-QLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELW 288
Query: 61 SEDLKDAQEKLELTEKKASDAEGDVAALNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
+ + +EK+ E+K + E + +I+ EE++ R +E++ +K+ E E
Sbjct: 289 NLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKM 348
Query: 121 DESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAE 180
E ++ E + + EEKM QE +++E +E + EE+ R + E+
Sbjct: 349 WRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQE---EEMWR-------QEEKIR 398
Query: 181 ERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAE 240
E+ E + K E++++ ++ E + EK + EE ++ +KL+E E + +
Sbjct: 399 EQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQ 458
Query: 241 FAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQ 276
E + + E+ I EEK+ + +E+ + L Q
Sbjct: 459 EEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQ 494
Score = 70.5 bits (171), Expect = 2e-12
Identities = 53/250 (21%), Positives = 121/250 (48%), Gaps = 6/250 (2%)
Query: 20 DRAEQAEADKKAAEDKCKQVEEE----LTHLQKKLKGTEDELDKYSEDLKDAQEKLELTE 75
++ ++ E + E+K ++ EE+ + +KK++ ++++ + E++ +EK+ E
Sbjct: 381 EKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELE 440
Query: 76 KKASDAEGDVAALNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAM 135
+ D E + + ++Q EE++ +E++ +K++E E+ E+ +K E +
Sbjct: 441 EMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQ-EEKIW 499
Query: 136 KDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAEERAEVSELKCGDLEE 195
+ EEKM QE ++ E + +E + K + K+ E L + EE+ + E++ +LEE
Sbjct: 500 EQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEE 559
Query: 196 ELKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDD 255
L + + L A + + I + K +EA++ + + L++ +
Sbjct: 560 RLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQQQDHYRGHLQQYVAA 619
Query: 256 LEEKLAQAKE 265
++ LA KE
Sbjct: 620 YQQ-LASGKE 628
Score = 70.1 bits (170), Expect = 2e-12
Identities = 48/225 (21%), Positives = 107/225 (47%), Gaps = 12/225 (5%)
Query: 20 DRAEQAEADKKAAEDKCKQVEEELTHLQKKLKGTEDELDKYSEDLKDA----QEKLELTE 75
++ + E + E+K + EE++ +K++ E+E+ + E +++ QEK+ E
Sbjct: 353 EKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQE 412
Query: 76 KKASDAEGDVAALNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAM 135
KK + + + + EE++ +E + +KL E E+ E E M+ E +
Sbjct: 413 KKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQ 472
Query: 136 KDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAEERAEVSELKCGDLEE 195
+ EEK++ QE + + + ++ ++ +E+ E ++ R EE+ E K + EE
Sbjct: 473 RQEEKIQEQEEKTWRQEKLLKQEEKIWEQ--------EEKMWRQEEKMWEQEEKMQEQEE 524
Query: 196 ELKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAE 240
+++ ++ E + EK + E ++ L ++L + +AE
Sbjct: 525 KMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAE 569
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 80.5 bits (197), Expect = 2e-15
Identities = 61/246 (24%), Positives = 118/246 (47%), Gaps = 19/246 (7%)
Query: 37 KQVEEELTHLQKKLKGTEDELDKYSEDLKDAQEKLELTEKKASDAEGDVAA--LNRRIQL 94
++++E+ LQ+KL+ E E + ++KD + KLE + + V A L + +Q
Sbjct: 214 EELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQS 273
Query: 95 VEEEL--------------DRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEK 140
V +L + +E++ +K++E E+ E E ++ E + + EEK
Sbjct: 274 VSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEK 333
Query: 141 MEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAEERAEVSELKCGDLEEELKNV 200
M QE +++E + + K E K+ E ++ R EE+ + K + EEE+
Sbjct: 334 MHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQ 393
Query: 201 TNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKL 260
++ E EK EK + E++++ +K++E E E + +LE+ + D EEKL
Sbjct: 394 EEKIREQE---EKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKL 450
Query: 261 AQAKEE 266
+ +E+
Sbjct: 451 REVEEK 456
Score = 79.0 bits (193), Expect = 5e-15
Identities = 65/293 (22%), Positives = 137/293 (46%), Gaps = 31/293 (10%)
Query: 1 MEAIKKKMQMLKLDKENAIDRAEQAEADKKAAEDKCKQVEEELTHLQKKLKGTEDELDKY 60
++++ K+Q + E +Q E E+K ++ EE++ + K++ E+++ +
Sbjct: 271 LQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQ 330
Query: 61 SEDLKDAQEKLELTEKKASDAEGDVAALNRRIQLVEEELDRAQERLATALQKLEE----- 115
E + + +EK+ E K E + +I+ EE++ R +E++ +K++E
Sbjct: 331 EEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEM 390
Query: 116 ---AEKAADE----------SERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKY 162
EK ++ E+ M+ + + + EE+M QE +++E + + ++ + K
Sbjct: 391 WRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKL 450
Query: 163 EEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLE----------AASE 212
EV K+ E +++ EE+ + E K + EE+ LK E E
Sbjct: 451 REVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEE 510
Query: 213 KYSEKEDK---YEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQ 262
K E+E+K EE+++ +K++E E R E + + E + +LEE+L +
Sbjct: 511 KMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGK 563
Score = 74.7 bits (182), Expect = 9e-14
Identities = 59/271 (21%), Positives = 130/271 (47%), Gaps = 9/271 (3%)
Query: 2 EAIKKKMQMLKLDKENAIDRAEQAEADKKAAEDKCKQVEEELTHLQKKLKGTEDELDKYS 61
+ + K++Q + + ++ E + E+K + EE++ ++K+ E ++ +
Sbjct: 265 DRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQE 324
Query: 62 EDLKDAQEKLELTEKKASDAEGDVAALNRRIQLVEEELDRAQERLATALQKLEEAEKAAD 121
E + +EK+ E+K + E + +I+ EE++ +E++ +K+ E ++
Sbjct: 325 EKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQ 384
Query: 122 ESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAEE 181
E E M E + + EEK QE ++ K + E+ D K E ++ E ++ EE
Sbjct: 385 EQEEEMWRQEEKIREQEEKR--QEKMWRQEKKMREQ-DEKIREQEEEMWRQEEKIRELEE 441
Query: 182 RAEVSELKCGDLEEELKNVTNNL----KSLEAASEKYSEKEDKYEEEIKLL--SDKLKEA 235
+ E K ++EE+++ + + ++ EK E+E+K + KLL +K+ E
Sbjct: 442 MMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQ 501
Query: 236 ETRAEFAERTVAKLEKTIDDLEEKLAQAKEE 266
E + E + + E+ + + EEK+ + +E+
Sbjct: 502 EEKMWRQEEKMWEQEEKMQEQEEKMQRQEEK 532
Score = 72.8 bits (177), Expect = 3e-13
Identities = 61/276 (22%), Positives = 133/276 (48%), Gaps = 11/276 (3%)
Query: 1 MEAIKKKMQMLKLDKENAIDRAEQAEADKKAAEDKCKQVEEELTHLQKKLKGTEDELDKY 60
+E+ K ++Q+ D + ++RA Q ++ + + ++ +EL + KL+ +E + +
Sbjct: 230 VESEKSEIQLNVKDLKRKLERA-QLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELW 288
Query: 61 SEDLKDAQEKLELTEKKASDAEGDVAALNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
+ + +EK+ E+K + E + +I+ EE++ R +E++ +K+ E E
Sbjct: 289 NLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKM 348
Query: 121 DESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAE 180
E ++ E + + EEKM QE +++E +E + EE+ R + E+
Sbjct: 349 WRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQE---EEMWR-------QEEKIR 398
Query: 181 ERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAE 240
E+ E + K E++++ ++ E + EK + EE ++ +KL+E E + +
Sbjct: 399 EQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQ 458
Query: 241 FAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQ 276
E + + E+ I EEK+ + +E+ + L Q
Sbjct: 459 EEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQ 494
Score = 70.5 bits (171), Expect = 2e-12
Identities = 53/250 (21%), Positives = 121/250 (48%), Gaps = 6/250 (2%)
Query: 20 DRAEQAEADKKAAEDKCKQVEEE----LTHLQKKLKGTEDELDKYSEDLKDAQEKLELTE 75
++ ++ E + E+K ++ EE+ + +KK++ ++++ + E++ +EK+ E
Sbjct: 381 EKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELE 440
Query: 76 KKASDAEGDVAALNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAM 135
+ D E + + ++Q EE++ +E++ +K++E E+ E+ +K E +
Sbjct: 441 EMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQ-EEKIW 499
Query: 136 KDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAEERAEVSELKCGDLEE 195
+ EEKM QE ++ E + +E + K + K+ E L + EE+ + E++ +LEE
Sbjct: 500 EQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEE 559
Query: 196 ELKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDD 255
L + + L A + + I + K +EA++ + + L++ +
Sbjct: 560 RLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQQQDHYRGHLQQYVAA 619
Query: 256 LEEKLAQAKE 265
++ LA KE
Sbjct: 620 YQQ-LASGKE 628
Score = 70.1 bits (170), Expect = 2e-12
Identities = 48/225 (21%), Positives = 107/225 (47%), Gaps = 12/225 (5%)
Query: 20 DRAEQAEADKKAAEDKCKQVEEELTHLQKKLKGTEDELDKYSEDLKDA----QEKLELTE 75
++ + E + E+K + EE++ +K++ E+E+ + E +++ QEK+ E
Sbjct: 353 EKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQE 412
Query: 76 KKASDAEGDVAALNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAM 135
KK + + + + EE++ +E + +KL E E+ E E M+ E +
Sbjct: 413 KKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQ 472
Query: 136 KDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAEERAEVSELKCGDLEE 195
+ EEK++ QE + + + ++ ++ +E+ E ++ R EE+ E K + EE
Sbjct: 473 RQEEKIQEQEEKTWRQEKLLKQEEKIWEQ--------EEKMWRQEEKMWEQEEKMQEQEE 524
Query: 196 ELKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAE 240
+++ ++ E + EK + E ++ L ++L + +AE
Sbjct: 525 KMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAE 569
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 77.8 bits (190), Expect = 1e-14
Identities = 55/251 (21%), Positives = 122/251 (48%), Gaps = 12/251 (4%)
Query: 23 EQAEADKKAAEDKCKQVEEELTHLQKKLKGTEDELDKYSEDLKDAQEKLELTEK------ 76
EQ E +K E+K + EE++ ++K++ E+++ + E +++ +E EK
Sbjct: 500 EQEEKIRKQ-EEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEK 558
Query: 77 -----KASDAEGDVAALNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIE 131
K + E + +I+ EE++ R +E++ +K +E E+ + E ++ E
Sbjct: 559 IWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQE 618
Query: 132 NRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAEERAEVSELKCG 191
+ + EEK+ QE +++E + + +E + K E K+ E +++ EE E K
Sbjct: 619 EKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIR 678
Query: 192 DLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEK 251
+ E++++ ++ E ++ EK + EE++ +K++E E + E + + E
Sbjct: 679 EQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEV 738
Query: 252 TIDDLEEKLAQ 262
+ EEK+ +
Sbjct: 739 RLRQQEEKMQE 749
Score = 77.0 bits (188), Expect = 2e-14
Identities = 65/268 (24%), Positives = 131/268 (48%), Gaps = 13/268 (4%)
Query: 2 EAIKKKMQMLKLDKENAIDRAEQAEADKKAAEDKCKQVEEELTHLQKKLKGTEDELDKYS 61
E ++++ +M+ +E + E+ +K E + K+ EEE Q+K + E ++ +
Sbjct: 377 EKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQE 436
Query: 62 EDLKDAQEKLELTEKKASDAEGDVAALNRRIQLVEEELDRAQERLATALQKLEEAEKAAD 121
E +++ +EK+ EKK E + + + ++ EEE + QE + +K+ E E+
Sbjct: 437 EKIREQEEKIREQEKKMWRQEEKI---HEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWR 493
Query: 122 ESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKY---EEVARKLVILEGELER 178
+ E+ M E + K EEK+ QE +++E + E + K EE R+ + E E+
Sbjct: 494 QKEK-MHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEK 552
Query: 179 AEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETR 238
E+ ++ E EE+ + + + E + EK + EE+I+ +K +E E +
Sbjct: 553 MHEQEKIWE------EEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEK 606
Query: 239 AEFAERTVAKLEKTIDDLEEKLAQAKEE 266
E + + E+ I + EEK+ + +E+
Sbjct: 607 MWKQEEKIREQEEKIQEQEEKIREQEEK 634
Score = 75.9 bits (185), Expect = 4e-14
Identities = 59/264 (22%), Positives = 126/264 (47%), Gaps = 6/264 (2%)
Query: 6 KKMQMLKLDKENAIDRAEQAEADKKAAEDKCKQVEEELTHLQKKLKGTEDELDKYSEDLK 65
K++Q + + ++ E + E+K + EE++ ++K++ E+++ + E ++
Sbjct: 272 KELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIR 331
Query: 66 DAQEKLELTEKKASDAEGDVAALNRRIQLVEEELDRAQERLATALQKLEEAEKAADESER 125
+ +EK+ E+ + E + + EE++ R +E + +K+ E+ E E
Sbjct: 332 EQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEE 391
Query: 126 GMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAEERAEV 185
++ +E + M ++EK+ QE + +E + I E+ R+ +E K+ E ++ EE+
Sbjct: 392 KIRELEEK-MHEQEKIREQEEKRQEEEKIREQEKRQEQEA--KMWRQEEKIREQEEKIRE 448
Query: 186 SELKCGDLEE---ELKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFA 242
E K EE E + + K E E++ +EEI +K+ E E +
Sbjct: 449 QEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQ 508
Query: 243 ERTVAKLEKTIDDLEEKLAQAKEE 266
E V + E+ I + EEK+ + +E+
Sbjct: 509 EEKVWRQEEKIREQEEKIREQEEK 532
Score = 75.5 bits (184), Expect = 5e-14
Identities = 53/238 (22%), Positives = 120/238 (50%), Gaps = 11/238 (4%)
Query: 33 EDKCKQVEEELTHLQKKLKGTEDELDKYSEDLKDAQEKLELTEKKASDAEG---DVAALN 89
++K + EE++ ++K+ E+++ + E +++ +EK+ E+K + E + ++
Sbjct: 495 KEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMH 554
Query: 90 RRIQLVEEELDRAQE-RLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQL 148
+ ++ EEE + QE ++ +K+ E E+ E ++ E + + EEKM QE ++
Sbjct: 555 EQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKI 614
Query: 149 KEAKHIAEEADRKYEEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLE 208
+E + +E + K E E ++ EE + E K G+ EE++ ++ E
Sbjct: 615 REQEEKIQEQEEKIRE-------QEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQE 667
Query: 209 AASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEE 266
+ EK + E++I+ +K++E E + E + + E+ + + EEK+ + +E+
Sbjct: 668 ETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEK 725
Score = 73.6 bits (179), Expect = 2e-13
Identities = 60/270 (22%), Positives = 131/270 (48%), Gaps = 17/270 (6%)
Query: 6 KKMQMLKLDKENAIDRAEQAEADKKAAEDKCKQVEEELTHLQKKLKGTEDELDKYSEDLK 65
++ + + +KE + R E+ +K E+K ++ EE + ++K++ E+ + + E ++
Sbjct: 338 RRQEEMMWEKEEKMRRQEEMMWEK---EEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIR 394
Query: 66 DAQEKL----ELTEKKASDAEGDVAALNRRIQLVEEELDRAQERLATALQKLEEAEKAAD 121
+ +EK+ ++ E++ E + + Q E ++ R +E++ +K+ E EK
Sbjct: 395 ELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMW 454
Query: 122 ESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEAD-----RKYEEVARKLVILEGEL 176
E K+ E +++EEK + QE ++ + I E+ + K E K+ E ++
Sbjct: 455 RQEE--KIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKV 512
Query: 177 ERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAE 236
R EE+ E K + EE++ ++ E E + E+E +E+E +K +E E
Sbjct: 513 WRQEEKIREQEEKIREQEEKMWRQEEKIREQE---EMWREEEKMHEQEKIWEEEKRQEQE 569
Query: 237 TRAEFAERTVAKLEKTIDDLEEKLAQAKEE 266
+ E + + E+ + EEK+ + +E+
Sbjct: 570 DKMWRQEEKIREQEEKVWRQEEKIREQEEK 599
Score = 70.9 bits (172), Expect = 1e-12
Identities = 52/236 (22%), Positives = 114/236 (48%), Gaps = 4/236 (1%)
Query: 2 EAIKKKMQMLKLDKENAIDRAEQAEADKKAAEDKCKQVEEELTHLQKKLKGTEDELDKYS 61
E I+++ + ++ +E + E+ ++ ++ K E+E ++K + ED++ +
Sbjct: 517 EKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQE 576
Query: 62 EDLKDAQEKLELTEKKASDAEGDVAALNRRIQLVEEELDRAQERLATALQKLEEAEKAAD 121
E +++ +EK+ E+K + E ++ EE++ +E++ +K+ E E+
Sbjct: 577 EKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIR 636
Query: 122 ESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAEE 181
E E + E + + EEKM QE +++E + + K E +K+ E ++ EE
Sbjct: 637 EQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEE 696
Query: 182 RAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDK-YEEEIKLLSDKLKEAE 236
+ E K + EE++ ++ E EK +E+K +E+E++L + K E
Sbjct: 697 MMQEQEEKMWEQEEKMCEQEEKMQEQE---EKMRRQEEKMWEQEVRLRQQEEKMQE 749
Score = 67.0 bits (162), Expect = 2e-11
Identities = 62/254 (24%), Positives = 119/254 (46%), Gaps = 35/254 (13%)
Query: 37 KQVEEELTHLQKKLKGTEDELDKYSEDLKDAQEKLE----LTEKKASDAEGD-------- 84
++++E+ LQ+KL+ E E + ++K+ + KLE L ++ AE D
Sbjct: 217 EELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQS 276
Query: 85 VAA-----------LNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENR 133
V+A NR Q EE++ R +E++ +K++E E+ E E ++ E +
Sbjct: 277 VSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEK 336
Query: 134 AMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAEERAEVSELKCGDL 193
+ EE M +E +++ + + E + K + E ++ R EE E K +L
Sbjct: 337 MRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIREL 396
Query: 194 EEELKNVTNNLKSLEAASEKYSEKEDKYEEEIKLL-SDKLKEAETRAEFAERTVAKLEKT 252
EE++ EK E+E+K +EE K+ +K +E E + E + + E+
Sbjct: 397 EEKMHE-----------QEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEK 445
Query: 253 IDDLEEKLAQAKEE 266
I + E+K+ + +E+
Sbjct: 446 IREQEKKMWRQEEK 459
Score = 66.6 bits (161), Expect = 2e-11
Identities = 46/213 (21%), Positives = 101/213 (47%)
Query: 2 EAIKKKMQMLKLDKENAIDRAEQAEADKKAAEDKCKQVEEELTHLQKKLKGTEDELDKYS 61
E I+++ +M + +++ E ++ EDK + EE++ ++K+ E+++ +
Sbjct: 538 EKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQE 597
Query: 62 EDLKDAQEKLELTEKKASDAEGDVAALNRRIQLVEEELDRAQERLATALQKLEEAEKAAD 121
E ++ +EK+ E+K + E + +I+ EE++ +E +K+ E E+
Sbjct: 598 EKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMC 657
Query: 122 ESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAEE 181
E E M+ E + EEK+ QE +++E + E + +E K+ E ++ EE
Sbjct: 658 EQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEE 717
Query: 182 RAEVSELKCGDLEEELKNVTNNLKSLEAASEKY 214
+ + E K EE++ L+ E +++
Sbjct: 718 KMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEH 750
Score = 35.4 bits (80), Expect = 0.057
Identities = 33/161 (20%), Positives = 72/161 (44%), Gaps = 23/161 (14%)
Query: 114 EEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILE 173
E+ +KA+ + + ++ + + Q+ +L+ A + ++ A ++ E AR L+
Sbjct: 108 EDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLI--- 164
Query: 174 GELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKY----------EE 223
R S G+LE+ L V K + E+ +++ D +E
Sbjct: 165 -------SRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDE 217
Query: 224 EIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAK 264
E+K + KL+E + + E ++++ + +L+ KL +AK
Sbjct: 218 ELKEKNAKLQE---KLQLVESEKSEIQLNVKELKRKLERAK 255
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 77.8 bits (190), Expect = 1e-14
Identities = 78/294 (26%), Positives = 131/294 (44%), Gaps = 31/294 (10%)
Query: 5 KKKMQMLKLDKENAIDRAEQAE--ADKKAAEDKCKQVEEELTHLQKKLKGTEDELDKYSE 62
K + QM +E RA + E A K +E K K +E E+ LQ++L +E +++E
Sbjct: 1649 KLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSE-RARRHAE 1707
Query: 63 DLKDAQEKLELTEKKASDAEGDVAALNR------RIQLVEEELDRAQERLATALQKLEEA 116
QE+ EL ++ + A G A L+ RI +EEEL+ Q + + +
Sbjct: 1708 -----QERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKT 1762
Query: 117 EKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEAD----RKYEEVARKLVIL 172
D + + A K + + E Q KE K +E + K++ L
Sbjct: 1763 TLQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQELEGAVKSKFKATISALEAK 1822
Query: 173 EGELE-----RAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEIKL 227
G+LE A+ERA ++L E++LK + ++ +++Y E+ +K +K
Sbjct: 1823 IGQLEEQLEQEAKERAAANKL-VRRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQ 1881
Query: 228 LSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQTLNEL 281
L +L+EAE A A + KL++ +DD A E N GL + + N L
Sbjct: 1882 LKRQLEEAEEEATRANASRRKLQRELDD-------ATEANEGLSREVSTLKNRL 1928
Score = 70.5 bits (171), Expect = 2e-12
Identities = 60/289 (20%), Positives = 133/289 (46%), Gaps = 11/289 (3%)
Query: 4 IKKKMQMLKLDKENAIDRAEQAEADKKAAEDKCKQVEEELTHLQKKLKGTEDELDKYSED 63
++ M+ L K++ + E K+A E + +++ +L L+ +L+ TED + +
Sbjct: 1509 LRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVN 1568
Query: 64 LKDAQEKLELT-EKKASDAEGDVAALNRRIQLVEEELD--RAQERLATALQK-----LEE 115
++ + + E + + E L ++++ +E EL+ R Q LA A +K L++
Sbjct: 1569 MQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKD 1628
Query: 116 AEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGE 175
E + + + + + K + +M+ + +L+EA+ +E + +E +KL LE E
Sbjct: 1629 LEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAE 1688
Query: 176 LERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEA 235
+ + +E SE E+E + + + + + +++ + E I L ++L+E
Sbjct: 1689 ILQLQEELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEE 1748
Query: 236 ETRAEFAERTVAKLEKTIDDLEEKLA---QAKEENVGLHQTLDQTLNEL 281
++ E K +D L +LA A +++ Q L++ EL
Sbjct: 1749 QSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKEL 1797
Score = 67.0 bits (162), Expect = 2e-11
Identities = 66/268 (24%), Positives = 130/268 (48%), Gaps = 28/268 (10%)
Query: 42 ELTHLQKKLKGTEDELDKYSEDLKDAQEKLELTEKKASDAEGDVAALNRRIQLVEEELDR 101
++T +++L+ ++EL K E + +LE E+K + L ++Q E
Sbjct: 846 QVTRQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAE 905
Query: 102 AQE---RLATALQKLEE----AEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHI 154
A+E RLA Q+LEE E +E E ++++N K + ++ E QL E +
Sbjct: 906 AEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGA 965
Query: 155 AEE-------ADRKYEEVARKLVILEG-------ELERAEERAEVSELKCGDLEEELKN- 199
++ A+ K +++ ++++LE E + E+R + + EE+ KN
Sbjct: 966 RQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNL 1025
Query: 200 --VTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLE 257
+ N + + + E+ +KE+K +E++ KL T + +A+L+ ID+L+
Sbjct: 1026 AKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTD---LQDQIAELQAQIDELK 1082
Query: 258 EKLAQAKEENVG-LHQTLDQTLNELNCI 284
+LA+ +EE G L + D+TL++ N +
Sbjct: 1083 LQLAKKEEELQGALARGDDETLHKNNAL 1110
Score = 66.2 bits (160), Expect = 3e-11
Identities = 63/316 (19%), Positives = 141/316 (44%), Gaps = 41/316 (12%)
Query: 7 KMQMLKLDKE--NAIDRAEQAEADKKAAEDKCKQVEEELTHLQKKLKGTEDELDKYSEDL 64
K+Q+ K ++E A+ R + K A ++++ ++ LQ+ + + +K +
Sbjct: 1082 KLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQK 1141
Query: 65 KDAQEKLELTEKKASDA--------------EGDVAALNRRIQLV----EEELDRAQERL 106
+D E+LE + + D E +VA L + ++ E ++ ++R
Sbjct: 1142 RDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRH 1201
Query: 107 ATALQKLEEAEKAA-------DESERGM-----------KVIENRAMKDEEKMEIQEMQL 148
ATAL++L E + A +++++G+ KV++ + E K + + Q+
Sbjct: 1202 ATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQV 1261
Query: 149 KEAKHIAEEADRKYEEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLE 208
+E E DR E+A K L+ EL+ E +E K ++ ++ + L+ +
Sbjct: 1262 QELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQ 1321
Query: 209 AASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAK---E 265
++ + ++ I+ L ++ + + E E LEK + L+ +LA K +
Sbjct: 1322 ELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVD 1381
Query: 266 ENVGLHQTLDQTLNEL 281
+++G ++L++ +L
Sbjct: 1382 DDLGTIESLEEAKKKL 1397
Score = 63.2 bits (152), Expect = 3e-10
Identities = 67/316 (21%), Positives = 141/316 (44%), Gaps = 39/316 (12%)
Query: 4 IKKKMQMLKLDKENAID----------RAEQAEAD-KKAAEDKCKQVEEELTHLQKKLKG 52
+ ++++ LK + E+ +D + EQ A+ KKA E++ K E ++ ++++
Sbjct: 1144 LSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHAT 1203
Query: 53 TEDELDKYSEDLKDAQEKLELTEKKASDAEGDVAALNRRIQLVEEELDRAQERLATALQK 112
+EL + E K + LE ++ ++A + +Q V+ E + +++L +Q+
Sbjct: 1204 ALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQE 1263
Query: 113 L------------EEAEKAA------DESERGMKVIENRAMKDEEKMEIQEMQLKEAKHI 154
L E AEKA+ D ++ E + +K + E QL++ + +
Sbjct: 1264 LHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQEL 1323
Query: 155 AEEADRKYEEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLE------ 208
+E R+ ++ ++ LE E +E+ E E +LE+++ + + L +
Sbjct: 1324 LQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDD 1383
Query: 209 -AASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEEN 267
E E + K ++ + LS +L+E + E+T +L++ +DDL L ++
Sbjct: 1384 LGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVA 1443
Query: 268 VGL---HQTLDQTLNE 280
L + DQ L E
Sbjct: 1444 SNLEKKQKKFDQLLAE 1459
Score = 60.1 bits (144), Expect = 2e-09
Identities = 59/268 (22%), Positives = 125/268 (46%), Gaps = 30/268 (11%)
Query: 12 KLDKENAIDRAEQAEADKKAAE--DKCKQVEEELTHLQKKLKGTEDELDKYSEDLKDAQE 69
KLD + A+ +E D+ E +K +++ EL ++ L+ E + K+++D +
Sbjct: 1256 KLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLES 1315
Query: 70 KLELTEKKASDAEGDVAALNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKV 129
+L+ T++ + L+ RI+ +EEE + QE + EE E+A E+ +
Sbjct: 1316 QLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQE-------QQEEEEEARKNLEKQVLA 1368
Query: 130 IENRAMKDEEKM-----------EIQEMQLKEAKHIAEEADRK---YEEVARKLVILEGE 175
++++ ++K+ E ++ LK+A+ +++ + K Y+++ + L+ E
Sbjct: 1369 LQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQE 1428
Query: 176 LERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEIK-------LL 228
L+ + +LE++ K L ++ S +Y+E+ D+ E E + L
Sbjct: 1429 LDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSL 1488
Query: 229 SDKLKEAETRAEFAERTVAKLEKTIDDL 256
+ L+EA E ER +L ++DL
Sbjct: 1489 ARALEEALEAKEEFERQNKQLRADMEDL 1516
Score = 58.5 bits (140), Expect = 6e-09
Identities = 64/299 (21%), Positives = 132/299 (44%), Gaps = 22/299 (7%)
Query: 2 EAIKKKMQMLKLDK--ENAIDRAEQAE-------ADKKAAEDKCKQVEEELTHLQKKLKG 52
EA +K+ + L L + E A++ E+ E AD + V + + L+K +
Sbjct: 1477 EAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRA 1536
Query: 53 TEDELDKYSEDLKDAQEKLELTEKKASDAEGDVAALNRRIQLVEEELDRAQERLATALQK 112
E ++++ L++ +++L+ TE E ++ A+ + + + D E L K
Sbjct: 1537 LEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIK 1596
Query: 113 LEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVIL 172
+A E ER + + A+ ++KMEI LK+ + E A++ +EV ++L L
Sbjct: 1597 QVRELEAELEDERKQRAL---AVASKKKMEID---LKDLEAQIEAANKARDEVIKQLRKL 1650
Query: 173 EGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEK-------EDKYEEEI 225
+ +++ + E + ++ + K LKSLEA + E+ E+E
Sbjct: 1651 QAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQER 1710
Query: 226 KLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQTLNELNCI 284
L+D++ + + +LE I LEE+L + + L+ +T +++ +
Sbjct: 1711 DELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTL 1769
Score = 57.8 bits (138), Expect = 1e-08
Identities = 56/290 (19%), Positives = 133/290 (45%), Gaps = 13/290 (4%)
Query: 1 MEAIKKKMQMLKLDKENAIDRAEQAEADKKAAEDKCKQVEEELTHLQKKLKGTEDELDKY 60
+ A K++++ + D E+ R E+ E + +++ K+++ + L+++L E K
Sbjct: 913 LAAKKQELEEILHDLES---RVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKL 969
Query: 61 SEDLKDAQEKLELTEKKASDAEGDVAALNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
+ A+ K++ E++ E + + +L+E+ + +LA +K + K
Sbjct: 970 QLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIR 1029
Query: 121 DESERGMKVIENRAMKDEE-KMEIQEMQLK------EAKHIAEEADRKYEEVARKLVILE 173
++ E + +E R K+E+ + E+++ + K + + E + +E+ +L E
Sbjct: 1030 NKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKE 1089
Query: 174 GELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLK 233
EL+ A R + L + + ++ + + L+ E +K E++ + LS++L+
Sbjct: 1090 EELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELE 1149
Query: 234 EAETRAEFAERTVAKLEKTIDDLEEKLAQAK---EENVGLHQTLDQTLNE 280
+T E T A ++ E+++A+ K EE H+ Q + +
Sbjct: 1150 ALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQ 1199
Score = 57.4 bits (137), Expect = 1e-08
Identities = 55/276 (19%), Positives = 126/276 (45%), Gaps = 14/276 (5%)
Query: 1 MEAIKKKMQMLKLDKENAIDRAEQAEADKKAAEDKCKQVEE-ELTHLQKKLKGTEDELDK 59
+E +KK L L +E +I E D+ AE + K+ + L ++ ++E ++
Sbjct: 1446 LEKKQKKFDQL-LAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFER 1504
Query: 60 YSEDLKDAQEKLELTEKKASDAEGDVAALNRRIQLVEEELDRAQERLATALQKLEEAEKA 119
++ L+ E L ++ ++ R ++ EE+ E L LQ E+A+
Sbjct: 1505 QNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLR 1564
Query: 120 ADESERGMKVIENRAM--KDEEKMEIQEMQLKEAKHIAEEA--DRKYEEVA----RKLVI 171
+ + + MK R + +DE+ E + + +K+ + + E +RK +A +K+ I
Sbjct: 1565 LEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEI 1624
Query: 172 ----LEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEIKL 227
LE ++E A + + + L+ ++K+ L+ A+ ++ + + E+++K
Sbjct: 1625 DLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKS 1684
Query: 228 LSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQA 263
L ++ + + +ER E+ D+L +++ +
Sbjct: 1685 LEAEILQLQEELASSERARRHAEQERDELADEITNS 1720
Score = 51.6 bits (122), Expect = 8e-07
Identities = 54/278 (19%), Positives = 126/278 (45%), Gaps = 24/278 (8%)
Query: 10 MLKLDKENAIDRAEQAEADKKAAEDKCKQVEEELT---HLQKKLKGTEDELDKYSEDLKD 66
+L+ ++ I A+ A + + +D + ++EE +L +++ E+E + E ++
Sbjct: 1295 LLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEE 1354
Query: 67 AQEKLELTEKKASDAEGDVAALNRRIQ---LVEEELDRAQERL---ATAL-QKLEEAEKA 119
+E + EK+ + +A +++ E L+ A+++L A AL Q+LEE A
Sbjct: 1355 EEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALA 1414
Query: 120 ADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERA 179
D+ E+ +NR ++ + + + ++ E+ +K++++ + +
Sbjct: 1415 YDKLEK----TKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEE 1470
Query: 180 EERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRA 239
+RAE E + SL A E+ E ++++E + K L +++ +
Sbjct: 1471 RDRAEA----------EAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSK 1520
Query: 240 EFAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQT 277
+ + V +LEK+ LE+++ + + + L L T
Sbjct: 1521 DDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQAT 1558
Score = 51.6 bits (122), Expect = 8e-07
Identities = 73/325 (22%), Positives = 141/325 (43%), Gaps = 54/325 (16%)
Query: 2 EAIKKKMQ--MLKLDK-ENAIDRAEQAEADKKAAEDKCKQVEEELTHLQKKLKGTEDEL- 57
EA+ ++++ L DK E +R +Q D D +QV L QKK D+L
Sbjct: 1402 EALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKF----DQLL 1457
Query: 58 -DKYSEDLKDAQEKLELTEKKASDAEGDVAALNRRIQLV---EEELDRAQERLATALQKL 113
++ S + A+E+ + E +A + E +L R ++ +EE +R ++L ++ L
Sbjct: 1458 AEEKSISARYAEER-DRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDL 1516
Query: 114 ----EEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKL 169
++ K E E+ + +E + E+M Q +L++ E+A + E + +
Sbjct: 1517 MSSKDDVGKNVHELEKSKRALEQQV----EEMRTQLEELEDELQATEDAKLRLEVNMQAM 1572
Query: 170 VI-----LEGELERAEERAEVSELKCGDLEEEL--------------KNVTNNLKSLEAA 210
L+ E+ EE+ + + +LE EL K + +LK LEA
Sbjct: 1573 KAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQ 1632
Query: 211 SEKYSEKEDKYEEEIKLLSDKLKEAETRAEFA--------------ERTVAKLEKTIDDL 256
E ++ D+ ++++ L ++K+ + E A E+ + LE I L
Sbjct: 1633 IEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQL 1692
Query: 257 EEKLAQAKEENVGLHQTLDQTLNEL 281
+E+LA ++ Q D+ +E+
Sbjct: 1693 QEELASSERARRHAEQERDELADEI 1717
Score = 45.8 bits (107), Expect = 4e-05
Identities = 45/193 (23%), Positives = 87/193 (45%), Gaps = 12/193 (6%)
Query: 48 KKLKGTEDELDKYSEDLKDAQEKLELTEKKASDAEGDVAALNRRIQLVEEELDRAQERLA 107
+K +L++ +++LK ++LE K S + ++AL +I +EE+L++ + A
Sbjct: 1781 QKSDNARQQLERQNKELKAKLQELEGAVK--SKFKATISALEAKIGQLEEQLEQEAKERA 1838
Query: 108 TALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVAR 167
A + + EK E ++ A + +E+ME ++K+ K EEA+ +
Sbjct: 1839 AANKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANA 1898
Query: 168 KLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLK---SLEAASEKYSEKEDKYEEE 224
L+ EL+ A E E L E+ + N L+ + +S + ++ E
Sbjct: 1899 SRRKLQRELDDATEANE-------GLSREVSTLKNRLRRGGPISFSSSRSGRRQLHLEGA 1951
Query: 225 IKLLSDKLKEAET 237
LSD E++T
Sbjct: 1952 SLELSDDDTESKT 1964
Score = 45.4 bits (106), Expect = 6e-05
Identities = 33/129 (25%), Positives = 59/129 (45%), Gaps = 4/129 (3%)
Query: 146 MQLKEAKHIAEEADRKYEEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLK 205
+Q+ + + D + +V K +EGELE E + + + L E+L+ T
Sbjct: 845 LQVTRQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFA 904
Query: 206 SLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKE 265
E + + K+ + EE + L +++E E R + + K++ I DLEE+L +
Sbjct: 905 EAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQL----D 960
Query: 266 ENVGLHQTL 274
E G Q L
Sbjct: 961 EEEGARQKL 969
>gi|157738667 FYVE and coiled-coil domain containing 1 [Homo sapiens]
Length = 1478
Score = 77.8 bits (190), Expect = 1e-14
Identities = 84/301 (27%), Positives = 137/301 (45%), Gaps = 53/301 (17%)
Query: 5 KKKMQMLKLDKENAIDRA---------EQAEADKKAAEDKCKQVEEELTHLQKKLKGTED 55
K +Q LK ++ A++RA E+ A ++ D+ +Q EEEL LQ++L +
Sbjct: 824 KTLVQQLK-EQNEALNRAHVQELLQCSEREGALQEERADEAQQREEELRALQEELSQAKC 882
Query: 56 ELDKYSEDLKDAQEKLELTEKKASDAEGDVAALNRRIQLVEEELDRAQERLATALQKLEE 115
++ + + QE+L A D A L ++ + E +R +E LA A+Q+L++
Sbjct: 883 SSEEAQLEHAELQEQLHR-------ANTDTAELGIQVCALTVEKERVEEALACAVQELQD 935
Query: 116 AEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGE 175
A++AA G++ A +EK +QE +LK AK A L L+ +
Sbjct: 936 AKEAASREREGLE--RQVAGLQQEKESLQE-KLKAAK-----------AAAGSLPGLQAQ 981
Query: 176 LERAEERAEVSELKCGDLEEELKNVTNNLK-SLEAASEKYSEKEDKYEEEIKLLSDKLKE 234
L +AE+RA+ L+E N LK L A Y + EE K L +L+E
Sbjct: 982 LAQAEQRAQ-------SLQEAAHQELNTLKFQLSAEIMDYQSRLKNAGEECKSLRGQLEE 1034
Query: 235 AETRAEFAERTVAKLEKTIDDLEEKLA--------------QAKEENVGLHQTLDQTLNE 280
+ + AE V KL+ T D+ EKL+ + +E L + L++T E
Sbjct: 1035 QGRQLQAAEEAVEKLKATQADMGEKLSCTSNHLAECQAAMLRKDKEGAALREDLERTQKE 1094
Query: 281 L 281
L
Sbjct: 1095 L 1095
Score = 59.3 bits (142), Expect = 4e-09
Identities = 61/295 (20%), Positives = 132/295 (44%), Gaps = 46/295 (15%)
Query: 10 MLKLDKENAIDRAEQAEADK--KAAEDKCKQVEEELTHLQKKLKG--------------- 52
+L + K +A+ AE + ++ E +C+Q+ EE+ Q+ +
Sbjct: 681 LLAVRKAKEAMKAQMAEKEAILQSKEGECQQLREEVEQCQQLAEARHRELRALESQCQQQ 740
Query: 53 -------------------TEDELDKYSEDLKDAQEKLELTEKKASDAEGDVAALNRRIQ 93
T++E + + L +Q +LE+ + + + V L +++
Sbjct: 741 TQLIEVLTAEKGQQGVGPPTDNEARELAAQLALSQAQLEVHQGEVQRLQAQVVDLQAKMR 800
Query: 94 LVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKH 153
++ D+ Q +L+ A L E + + + + + +++ + +E L+E +
Sbjct: 801 AALDDQDKVQSQLSMAEAVLREHKTLVQQLKEQNEALNRAHVQELLQCSEREGALQEER- 859
Query: 154 IAEEADRKYEEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEK 213
A+EA ++ EE L L+ EL +A+ +E ++L+ +L+E+L + L
Sbjct: 860 -ADEAQQREEE----LRALQEELSQAKCSSEEAQLEHAELQEQLHRANTDTAELGIQVCA 914
Query: 214 YSEKEDKYEEEIKLLSDKLKEAETRA----EFAERTVAKLEKTIDDLEEKLAQAK 264
+ ++++ EE + +L++A+ A E ER VA L++ + L+EKL AK
Sbjct: 915 LTVEKERVEEALACAVQELQDAKEAASREREGLERQVAGLQQEKESLQEKLKAAK 969
Score = 58.9 bits (141), Expect = 5e-09
Identities = 54/239 (22%), Positives = 107/239 (44%), Gaps = 31/239 (12%)
Query: 37 KQVEEELTHLQKKLKGTEDELDKYSEDLKDAQEKLELTEKKA---SDAEGDVAALNRRIQ 93
+++E L L ++L+ T D LDK ++ L L + ++KA SD +G R +
Sbjct: 338 RRLESMLQPLAQELEATRDSLDKKNQHLASFPGWLAMAQQKADTASDTKG-------RQE 390
Query: 94 LVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKH 153
+ + + + L LQ LE +E NR + + ++E+QLKE
Sbjct: 391 PIPSDAAQEMQELGEKLQALERERTKVEEV--------NRQQSAQLEQLVKELQLKE--- 439
Query: 154 IAEEADRKYEEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEK 213
+A E + +++ L+ EL + A+ + +L + L L ++
Sbjct: 440 ---DARASLERLVKEMAPLQEELSGKGQEADQLWRRLQELLAHTSSWEEELAELRREKKQ 496
Query: 214 YSEKEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEENVGLHQ 272
E+++ E+E++ L+ +L +F E +A++ + + DLEE+ Q ++ L Q
Sbjct: 497 QQEEKELLEQEVRSLTRQL-------QFLETQLAQVSQHVSDLEEQKKQLIQDKDHLSQ 548
Score = 56.2 bits (134), Expect = 3e-08
Identities = 62/282 (21%), Positives = 123/282 (43%), Gaps = 22/282 (7%)
Query: 6 KKMQMLKLDKENAIDRAEQAEADKKAAEDKCKQVEEELTHLQKKLKGTEDELDKYSEDLK 65
+++Q L + + + +KK +++ + +E+E+ L ++L+ E +L + S+ +
Sbjct: 471 RRLQELLAHTSSWEEELAELRREKKQQQEEKELLEQEVRSLTRQLQFLETQLAQVSQHVS 530
Query: 66 DAQEKLELTEKKASDAEGDVAALNRRIQLVEEELDRAQER---LATALQKLEEAEKAADE 122
D +E+ + + V L R EL A E+ L L+EA +E
Sbjct: 531 DLEEQKKQLIQDKDHLSQQVGMLERLAGPPGPELPVAGEKNEALVPVNSSLQEAWGKPEE 590
Query: 123 SERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAEER 182
+RG++ A D+ K++ + Q +E + E +++ + V + +LEG+L+ +
Sbjct: 591 EQRGLQ----EAQLDDTKVQ-EGSQEEELRQANRELEKELQNVVGRNQLLEGKLQALQAD 645
Query: 183 AEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFA 242
+ L++ + +L SLEA D+ E + L K KEA +A+ A
Sbjct: 646 YQA-------LQQRESAIQGSLASLEAEQASIRHLGDQMEASL-LAVRKAKEA-MKAQMA 696
Query: 243 ERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQTLNELNCI 284
E+ E + E + Q +EE Q + EL +
Sbjct: 697 EK-----EAILQSKEGECQQLREEVEQCQQLAEARHRELRAL 733
Score = 54.7 bits (130), Expect = 9e-08
Identities = 68/300 (22%), Positives = 128/300 (42%), Gaps = 37/300 (12%)
Query: 9 QMLKLDKENAIDRA------EQAEADKK----AAEDKCKQVEEELTHLQKKLKGTEDELD 58
+M +LD+EN RA EQ + +++ AAED + LT L +L+ +
Sbjct: 252 RMQQLDRENQELRAAVSQQGEQLQTERERGRTAAEDNVR-----LTCLVAELQKQWEVTQ 306
Query: 59 KYSEDLKDAQEKLELTEKKASDAEGDVAALNRRI----QLVEEELDRAQERLATALQKL- 113
+K+ Q L+ E A++ E D RR+ Q + +EL+ ++ L Q L
Sbjct: 307 ATQNTVKELQTCLQGLELGAAEKEEDYHTALRRLESMLQPLAQELEATRDSLDKKNQHLA 366
Query: 114 ----------EEAEKAADESERGMKVIENRAMKDEE---KMEIQEMQLKEAKHIAEEADR 160
++A+ A+D R + + A + +E K++ E + + + + +
Sbjct: 367 SFPGWLAMAQQKADTASDTKGRQEPIPSDAAQEMQELGEKLQALERERTKVEEVNRQQSA 426
Query: 161 KYEEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDK 220
+ E++ ++L + E RA V E+ L+EEL L ++
Sbjct: 427 QLEQLVKELQLKEDA--RASLERLVKEM--APLQEELSGKGQEADQLWRRLQELLAHTSS 482
Query: 221 YEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQTLNE 280
+EEE+ L + K+ + E E+ V L + + LE +LAQ + L + Q + +
Sbjct: 483 WEEELAELRREKKQQQEEKELLEQEVRSLTRQLQFLETQLAQVSQHVSDLEEQKKQLIQD 542
Score = 42.7 bits (99), Expect = 4e-04
Identities = 29/132 (21%), Positives = 61/132 (46%), Gaps = 10/132 (7%)
Query: 30 KAAEDKCKQVEEELTHLQKKLKGTEDELDKYSEDLKDAQEKLELTEKKASDAEGDVAALN 89
K A ++CK + +L ++L+ E+ ++K D EKL T ++ + + +
Sbjct: 1019 KNAGEECKSLRGQLEEQGRQLQAAEEAVEKLKATQADMGEKLSCTSNHLAECQAAMLRKD 1078
Query: 90 RRIQLVEEELDRAQERLATALQKLEE-----AEKAADESERGMKVIE-----NRAMKDEE 139
+ + E+L+R Q+ L A K++E ++ + K++ NR K E
Sbjct: 1079 KEGAALREDLERTQKELEKATTKIQEYYNKLCQEVTNRERNDQKMLADLDDLNRTKKYLE 1138
Query: 140 KMEIQEMQLKEA 151
+ I+ ++ K+A
Sbjct: 1139 ERLIELLRDKDA 1150
Score = 39.7 bits (91), Expect = 0.003
Identities = 52/274 (18%), Positives = 106/274 (38%), Gaps = 16/274 (5%)
Query: 18 AIDRAEQAEADKKAAEDKCKQVEEELTHLQKKLKGTEDELDKYSEDLKDAQEKLELTEKK 77
A +A+ A K E +E+ L +KL+ E E K E + +LE K+
Sbjct: 375 AQQKADTASDTKGRQEPIPSDAAQEMQELGEKLQALERERTKVEEVNRQQSAQLEQLVKE 434
Query: 78 AS---DAEGDVAALNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRA 134
DA + L + + ++EEL + ++L+E E + +
Sbjct: 435 LQLKEDARASLERLVKEMAPLQEELSGKGQEADQLWRRLQELLAHTSSWEEELAELRREK 494
Query: 135 MKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAEERAEVSELKCGDLE 194
+ +E+ E+ E +++ + + + +V++ + LE + ++ + + + G LE
Sbjct: 495 KQQQEEKELLEQEVRSLTRQLQFLETQLAQVSQHVSDLEEQKKQLIQDKDHLSQQVGMLE 554
Query: 195 E-------ELKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFAERTVA 247
EL ++L + E K EEE + L E + + +
Sbjct: 555 RLAGPPGPELPVAGEKNEALVPVNSSLQEAWGKPEEEQRGLQ------EAQLDDTKVQEG 608
Query: 248 KLEKTIDDLEEKLAQAKEENVGLHQTLDQTLNEL 281
E+ + +L + + VG +Q L+ L L
Sbjct: 609 SQEEELRQANRELEKELQNVVGRNQLLEGKLQAL 642
>gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens]
Length = 1417
Score = 77.4 bits (189), Expect = 1e-14
Identities = 76/311 (24%), Positives = 142/311 (45%), Gaps = 41/311 (13%)
Query: 11 LKLDKENAIDRAEQAEADKKAAEDKCKQVEEELTHLQKKLKGTEDELDKYSED------- 63
L++ KE + Q E +K+ E + K+ EE+ LQK+LK L + SE
Sbjct: 851 LEICKEELVLHLNQLEGNKEKFEKQLKKKSEEVYCLQKELKIKNHSLQETSEQNVILQHT 910
Query: 64 LKDAQEKLELTEKKASDAEGDVAALNRRIQLVEEELDRAQERLATALQKLEE-AEKAADE 122
L+ Q+ L+ + + E L +++ +E+EL + +E A L+K+EE E AA E
Sbjct: 911 LQQQQQMLQQETIRNGELEDTQTKLEKQVSKLEQELQKQRESSAEKLRKMEEKCESAAHE 970
Query: 123 SE-RGMKVIE----NRAMK---DEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVIL-- 172
++ + KVIE R +K D+ K E+ +M+ KE H+ + + K +++ +IL
Sbjct: 971 ADLKRQKVIELTGTARQVKIEMDQYKEELSKME-KEIMHLKRDGENKAMHLSQLDMILDQ 1029
Query: 173 ----------------------EGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAA 210
E EL A ++ EV E + + ELK+ L+ L
Sbjct: 1030 TKTELEKKTNAVKELEKLQHSTETELTEALQKREVLETELQNAHGELKSTLRQLQELRDV 1089
Query: 211 SEKYSEKEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEENVGL 270
+K ++ IK L+ +L+E + E ++ + ++++ + + +L Q + L
Sbjct: 1090 LQKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQELLEMDQALKERNWELKQRAAQVTHL 1149
Query: 271 HQTLDQTLNEL 281
T+ + E+
Sbjct: 1150 DMTIREHRGEM 1160
Score = 70.1 bits (170), Expect = 2e-12
Identities = 56/284 (19%), Positives = 130/284 (45%), Gaps = 11/284 (3%)
Query: 1 MEAIKKKMQMLKLDKENAIDRAEQAEADKKAAEDKCKQVEEELTHLQKKLKGTEDELDKY 60
+ ++K++ LK D EN Q + + + ++ + L+K TE EL
Sbjct: 999 LSKMEKEIMHLKRDGENKAMHLSQLDMILDQTKTELEKKTNAVKELEKLQHSTETELT-- 1056
Query: 61 SEDLKDAQEKLELTEKKASDAEGDVAALNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
+A +K E+ E + +A G++ + R++Q + + L +AQ L +++
Sbjct: 1057 -----EALQKREVLETELQNAHGELKSTLRQLQELRDVLQKAQLSLEEKYTTIKDLTAEL 1111
Query: 121 DESERGMKVIENRAMKDEEKMEIQEMQLKE----AKHIAEEADRKYEEVARKLVILEGEL 176
E + ++ + ++ ++ ++ + +LK+ H+ E+ +K++ LEG L
Sbjct: 1112 RECKMEIEDKKQELLEMDQALKERNWELKQRAAQVTHLDMTIREHRGEMEQKIIKLEGTL 1171
Query: 177 ERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAE 236
E++E + + L ++L+N L+ E + ++ + ++EI+ ++KE E
Sbjct: 1172 EKSELELKECNKQIESLNDKLQNAKEQLREKEFIMLQNEQEISQLKKEIERTQQRMKEME 1231
Query: 237 TRAEFAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQTLNE 280
+ + E+ +A K DL ++L +E+ H L + ++
Sbjct: 1232 SVMKEQEQYIATQYKEAIDLGQELRLTREQVQNSHTELAEARHQ 1275
Score = 60.8 bits (146), Expect = 1e-09
Identities = 60/270 (22%), Positives = 123/270 (45%), Gaps = 13/270 (4%)
Query: 5 KKKMQMLKLDKENAIDRAEQAEADKKAAEDKCKQVEEELTHLQKK---LKGT----EDEL 57
K + Q+ KL++E R AE +K E+KC+ E ++K L GT + E+
Sbjct: 934 KLEKQVSKLEQELQKQRESSAEKLRKM-EEKCESAAHEADLKRQKVIELTGTARQVKIEM 992
Query: 58 DKYSEDLKDAQEKLELTEKKASDAEGDVAALNRRIQLVEEELDRAQERLATALQKLEEA- 116
D+Y E+L ++++ ++ + ++ L+ + + EL++ + L+KL+ +
Sbjct: 993 DQYKEELSKMEKEIMHLKRDGENKAMHLSQLDMILDQTKTELEK-KTNAVKELEKLQHST 1051
Query: 117 EKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGEL 176
E E+ + +V+E +++ QL+E + + ++A EE + L EL
Sbjct: 1052 ETELTEALQKREVLETELQNAHGELKSTLRQLQELRDVLQKAQLSLEEKYTTIKDLTAEL 1111
Query: 177 ERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAE 236
+ E + + ++++ LK LK A + + + E + K+ + E
Sbjct: 1112 RECKMEIEDKKQELLEMDQALKERNWELKQRAA---QVTHLDMTIREHRGEMEQKIIKLE 1168
Query: 237 TRAEFAERTVAKLEKTIDDLEEKLAQAKEE 266
E +E + + K I+ L +KL AKE+
Sbjct: 1169 GTLEKSELELKECNKQIESLNDKLQNAKEQ 1198
Score = 55.1 bits (131), Expect = 7e-08
Identities = 51/244 (20%), Positives = 109/244 (44%), Gaps = 23/244 (9%)
Query: 30 KAAEDKCKQVEEELTHLQKKLKGTEDELDKYSEDLKDAQEKLELTEKKASDAEGDVAALN 89
KA +++ + ++ L L+ ++EL + L+ +EK E KK S+ +V L
Sbjct: 831 KALQNQVSEETIKVRQLDSALEICKEELVLHLNQLEGNKEKFEKQLKKKSE---EVYCLQ 887
Query: 90 RRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLK 149
+ +++ L E+ L++ + ++++ +++ E + Q K
Sbjct: 888 KELKIKNHSLQETSEQNVILQHTLQQQQ----------QMLQQETIRNGELEDTQTKLEK 937
Query: 150 EAKHIAEEADRKYEEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEA 209
+ + +E ++ E A KL +E E+ E A ++LK +++ +T + ++
Sbjct: 938 QVSKLEQELQKQRESSAEKLRKME---EKCESAAHEADLK----RQKVIELTGTARQVKI 990
Query: 210 ASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEENVG 269
++Y E+ K E+EI L ++ E +A + L++T +LE+K KE
Sbjct: 991 EMDQYKEELSKMEKEIMHLK---RDGENKAMHLSQLDMILDQTKTELEKKTNAVKELEKL 1047
Query: 270 LHQT 273
H T
Sbjct: 1048 QHST 1051
Score = 52.0 bits (123), Expect = 6e-07
Identities = 56/252 (22%), Positives = 113/252 (44%), Gaps = 38/252 (15%)
Query: 33 EDKCKQVEEELTHLQKKLKGTEDELDKYS----EDLKDAQEKLELTEKKASDAEGDVAAL 88
E+ CK + T QKK + D++ S +++K +EKL ++ + +L
Sbjct: 200 ENVCK-ISGSSTDFQKKPR---DKMFSSSAPVDQEIKSLREKLNKLRQQNACLVTQNHSL 255
Query: 89 NRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQL 148
+ + + EL +++ +++ LE A++ A + ++E + + E ++ Q+ L
Sbjct: 256 MTKFESIHFELTQSRAKVSM----LESAQQQA----ASVPILEEQIINLEAEVSAQDKVL 307
Query: 149 KEAKHIAEEADRKYEEVARKLVILEGELERAEERAEVSELKCGDLE-------------E 195
+EA++ E++ + +++E E E + E +LK LE E
Sbjct: 308 REAENKLEQSQK---------MVIEKEQSLQESKEECIKLKVDLLEQTKQGKRAERQRNE 358
Query: 196 ELKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDD 255
L N K+ + +K +EK +K + E ++L L E + + + ++
Sbjct: 359 ALYNAEELSKAFQQYKKKVAEKLEKVQAEEEILERNLTNCEKENKRLQERCGLYKSELEI 418
Query: 256 LEEKLAQAKEEN 267
L+EKL Q KEEN
Sbjct: 419 LKEKLRQLKEEN 430
Score = 50.8 bits (120), Expect = 1e-06
Identities = 61/281 (21%), Positives = 115/281 (40%), Gaps = 21/281 (7%)
Query: 6 KKMQMLKLDKENAI----DRAEQAEADKKAAEDKCKQVEEELTHLQKKLKGTEDELDKYS 61
+K Q L+ KE I D EQ + K+A +Q E L + ++ K + K +
Sbjct: 323 EKEQSLQESKEECIKLKVDLLEQTKQGKRAE----RQRNEALYNAEELSKAFQQYKKKVA 378
Query: 62 EDLKDAQEKLELTEKKASDAEGDVAALNRRIQLVEEELDRAQERLATALQKLEEAEKAAD 121
E L+ Q + E+ E+ ++ E + L R L + EL+ +E+L + +
Sbjct: 379 EKLEKVQAEEEILERNLTNCEKENKRLQERCGLYKSELEILKEKL----------RQLKE 428
Query: 122 ESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAEE 181
E+ G + + A+K+ E M + + E + K +E+ R L E +
Sbjct: 429 ENNNGKEKLRIMAVKNSEVMAQLTESRQSILKLESELENK-DEILRDKFSLMNENRELKV 487
Query: 182 RAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAEF 241
R + ++E+++ L+SLE + K + + + L ++ + +
Sbjct: 488 RVAAQNERLDLCQQEIESSRVELRSLEKIISQLPLKRELFGFKSYLSKYQMSSFSNKEDR 547
Query: 242 AERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQTLNELN 282
+ I +L KLA + E LH L T N+L+
Sbjct: 548 CIGCCEANKLVISELRIKLAIKEAEIQKLHANL--TANQLS 586
Score = 48.9 bits (115), Expect = 5e-06
Identities = 64/307 (20%), Positives = 130/307 (42%), Gaps = 35/307 (11%)
Query: 4 IKKKMQMLKLDKENAIDRAEQAEADKKAAEDKCKQVEEELTHLQKKLKGTEDELDKYSED 63
+ +K++ ++ ++E E + K +++C + EL L++KL+ ++E + E
Sbjct: 377 VAEKLEKVQAEEEILERNLTNCEKENKRLQERCGLYKSELEILKEKLRQLKEENNNGKEK 436
Query: 64 L-----KDAQEKLELTE------KKASDAEGDVAALNRRIQLVEEELDRAQERLATALQK 112
L K+++ +LTE K S+ E L + L+ E + + R+A ++
Sbjct: 437 LRIMAVKNSEVMAQLTESRQSILKLESELENKDEILRDKFSLMNENRE-LKVRVAAQNER 495
Query: 113 LEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEV-----AR 167
L+ ++ + S ++ +E + K E+ + +K+ K + A
Sbjct: 496 LDLCQQEIESSRVELRSLEKIISQLPLKRELFGFKSYLSKYQMSSFSNKEDRCIGCCEAN 555
Query: 168 KLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYE----E 223
KLVI E ++ A + AE+ +L N+T N S + S++ K E
Sbjct: 556 KLVISELRIKLAIKEAEIQKLHA--------NLTANQLSQSLITCNDSQESSKLSSLETE 607
Query: 224 EIKLLSDKLKEA------ETRAEFAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQT 277
+KL ++ E+ T + E+ +L I++L KL Q + EN L +
Sbjct: 608 PVKLGGHQVAESVKDQNQHTMNKQYEKERQRLVTGIEELRTKLIQIEAENSDLKVNMAHR 667
Query: 278 LNELNCI 284
++ I
Sbjct: 668 TSQFQLI 674
Score = 48.9 bits (115), Expect = 5e-06
Identities = 47/266 (17%), Positives = 121/266 (45%), Gaps = 15/266 (5%)
Query: 1 MEAIKKKMQMLKLDKENAIDRAEQAEADKKAAEDKCKQVEEELTHLQKKLKGTEDELDKY 60
++ ++ +Q +L E + A+ + + + + ++EL + + LK EL +
Sbjct: 1083 LQELRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQELLEMDQALKERNWELKQR 1142
Query: 61 SEDLKDAQEKLELTEKK-ASDAEGDVAALNRRIQLVEEELDRAQERLATALQKLEEAEKA 119
+ + L++T ++ + E + L ++ E EL +++ + KL+ A++
Sbjct: 1143 AAQVTH----LDMTIREHRGEMEQKIIKLEGTLEKSELELKECNKQIESLNDKLQNAKEQ 1198
Query: 120 ADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERA 179
E E M E + ++++E + ++KE + + +E ++ ++ + L EL
Sbjct: 1199 LREKEFIMLQNEQEISQLKKEIERTQQRMKEMESVMKEQEQYIATQYKEAIDLGQELRLT 1258
Query: 180 EERAEVSELKCGD-------LEEELKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKL 232
E+ + S + + + E++ +++ L+ ++ S++ + EE L + K+
Sbjct: 1259 REQVQNSHTELAEARHQQVQAQREIERLSSELEDMKQLSKEKDAHGNHLAEE--LGASKV 1316
Query: 233 KEAETRAEFAERTVAKLEKTIDDLEE 258
+EA A + + KL ++ L+E
Sbjct: 1317 REAHLEARM-QAEIKKLSAEVESLKE 1341
Score = 47.4 bits (111), Expect = 1e-05
Identities = 55/259 (21%), Positives = 104/259 (40%), Gaps = 31/259 (11%)
Query: 24 QAEADKKAAEDKCKQVEEELTHLQKKLKGTEDELDKYSEDLKDAQEKLELTEKKASDAEG 83
+ E K + V+++ H K E E + +++ + KL E + SD +
Sbjct: 605 ETEPVKLGGHQVAESVKDQNQHTMNKQY--EKERQRLVTGIEELRTKLIQIEAENSDLKV 662
Query: 84 DVAALNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEI 143
++A + QL++EEL EKA++ S+ +E+ K ++
Sbjct: 663 NMAHRTSQFQLIQEEL----------------LEKASNSSK-----LESEMTKKCSQLLT 701
Query: 144 QEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNN 203
E QL+E K +A Y +A K LE EL E+ E E++
Sbjct: 702 LEKQLEE-KIVA------YSSIAAKNAELEQELMEKNEKIRSLETNINTEHEKICLAFEK 754
Query: 204 LKSLEAASEKYSEKE-DKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQ 262
K + K EK+ ++ E +++ + KE E ++ + + ++ L+ L +
Sbjct: 755 AKKIHLEQHKEMEKQIERLEAQLEKKDQQFKEQEKTMSMLQQDIICKQHHLESLDRLLTE 814
Query: 263 AKEENVGLHQTLDQTLNEL 281
+K E + D+ L L
Sbjct: 815 SKGEMKKENMKKDEALKAL 833
Score = 32.3 bits (72), Expect = 0.48
Identities = 24/124 (19%), Positives = 55/124 (44%), Gaps = 10/124 (8%)
Query: 12 KLDKENAIDRAEQAEADKKAAEDKCKQVEEELTHLQKKLKGTEDELDKYSEDLKDA---- 67
+L+ + + + A + A E +V E HL+ +++ +L E LK+A
Sbjct: 1289 ELEDMKQLSKEKDAHGNHLAEELGASKVRE--AHLEARMQAEIKKLSAEVESLKEAYHME 1346
Query: 68 ----QEKLELTEKKASDAEGDVAALNRRIQLVEEELDRAQERLATALQKLEEAEKAADES 123
QE + A + V LN +++ + EL+ AQ+ ++ Q++++ + + +
Sbjct: 1347 MISHQENHAKWKISADSQKSSVQQLNEQLEKAKLELEEAQDTVSNLHQQVQDRNEVIEAA 1406
Query: 124 ERGM 127
+
Sbjct: 1407 NEAL 1410
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.302 0.122 0.300
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,998,126
Number of Sequences: 37866
Number of extensions: 438764
Number of successful extensions: 17305
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 769
Number of HSP's successfully gapped in prelim test: 1021
Number of HSP's that attempted gapping in prelim test: 3646
Number of HSP's gapped (non-prelim): 6843
length of query: 284
length of database: 18,247,518
effective HSP length: 101
effective length of query: 183
effective length of database: 14,423,052
effective search space: 2639418516
effective search space used: 2639418516
T: 11
A: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.8 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.