Search of human proteins with 223029440

Search of human proteins with 223029440

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|223029440 mothers against decapentaplegic homolog 3 isoform
2 [Homo sapiens]
         (320 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|5174513 mothers against decapentaplegic homolog 3 isoform 1 [...   680   0.0  
gi|223029442 mothers against decapentaplegic homolog 3 isoform 3...   680   0.0  
gi|223029440 mothers against decapentaplegic homolog 3 isoform 2...   680   0.0  
gi|51173730 Sma- and Mad-related protein 2 isoform 1 [Homo sapiens]   619   e-177
gi|5174511 Sma- and Mad-related protein 2 isoform 1 [Homo sapiens]    619   e-177
gi|209693426 Sma- and Mad-related protein 2 isoform 2 [Homo sapi...   619   e-177
gi|223029444 mothers against decapentaplegic homolog 3 isoform 4...   487   e-138
gi|47778931 SMAD, mothers against DPP homolog 5 [Homo sapiens]        413   e-115
gi|47778929 SMAD, mothers against DPP homolog 5 [Homo sapiens]        413   e-115
gi|47778925 SMAD, mothers against DPP homolog 5 [Homo sapiens]        413   e-115
gi|51173727 Sma- and Mad-related protein 1 [Homo sapiens]             409   e-114
gi|5174509 Sma- and Mad-related protein 1 [Homo sapiens]              409   e-114
gi|5174519 SMAD family member 9 isoform b [Homo sapiens]              404   e-113
gi|187828357 SMAD family member 9 isoform a [Homo sapiens]            397   e-111
gi|4885457 mothers against decapentaplegic homolog 4 [Homo sapiens]   180   2e-45
gi|92859871 SMAD family member 6 isoform 1 [Homo sapiens]             111   1e-24
gi|218749837 SMAD family member 6 isoform 2 [Homo sapiens]            101   8e-22
gi|5174517 SMAD family member 7 [Homo sapiens]                         97   2e-20
gi|146134388 YLP motif containing 1 [Homo sapiens]                     35   0.12 
gi|239757414 PREDICTED: hypothetical protein XP_002345432 [Homo ...    34   0.20 
gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [...    33   0.44 
gi|217416343 fibrosin-like 1 [Homo sapiens]                            32   0.58 
gi|125858485 hypothetical protein LOC80209 isoform 2 [Homo sapiens]    32   0.75 
gi|125656155 hypothetical protein LOC80209 isoform 1 [Homo sapiens]    32   0.75 
gi|157168329 formin 1 [Homo sapiens]                                   31   1.3  
gi|154689780 son of sevenless homolog 2 [Homo sapiens]                 31   1.3  
gi|34452173 integrin alpha X precursor [Homo sapiens]                  31   1.3  
gi|58219024 hypothetical protein LOC352999 [Homo sapiens]              31   1.7  
gi|11276067 snail 2 [Homo sapiens]                                     30   2.2  
gi|110611908 mitogen-activated protein kinase kinase kinase kina...    30   2.2  

>gi|5174513 mothers against decapentaplegic homolog 3 isoform 1
           [Homo sapiens]
          Length = 425

 Score =  680 bits (1755), Expect = 0.0
 Identities = 320/320 (100%), Positives = 320/320 (100%)

Query: 1   MELCEFAFNMKKDEVCVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTN 60
           MELCEFAFNMKKDEVCVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTN
Sbjct: 106 MELCEFAFNMKKDEVCVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTN 165

Query: 61  FPAGIEPQSNIPETPPPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVT 120
           FPAGIEPQSNIPETPPPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVT
Sbjct: 166 FPAGIEPQSNIPETPPPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVT 225

Query: 121 YCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVEL 180
           YCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVEL
Sbjct: 226 YCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVEL 285

Query: 181 TRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNN 240
           TRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNN
Sbjct: 286 TRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNN 345

Query: 241 QEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQ 300
           QEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQ
Sbjct: 346 QEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQ 405

Query: 301 WLDKVLTQMGSPSIRCSSVS 320
           WLDKVLTQMGSPSIRCSSVS
Sbjct: 406 WLDKVLTQMGSPSIRCSSVS 425


>gi|223029442 mothers against decapentaplegic homolog 3 isoform 3
           [Homo sapiens]
          Length = 381

 Score =  680 bits (1755), Expect = 0.0
 Identities = 320/320 (100%), Positives = 320/320 (100%)

Query: 1   MELCEFAFNMKKDEVCVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTN 60
           MELCEFAFNMKKDEVCVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTN
Sbjct: 62  MELCEFAFNMKKDEVCVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTN 121

Query: 61  FPAGIEPQSNIPETPPPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVT 120
           FPAGIEPQSNIPETPPPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVT
Sbjct: 122 FPAGIEPQSNIPETPPPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVT 181

Query: 121 YCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVEL 180
           YCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVEL
Sbjct: 182 YCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVEL 241

Query: 181 TRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNN 240
           TRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNN
Sbjct: 242 TRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNN 301

Query: 241 QEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQ 300
           QEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQ
Sbjct: 302 QEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQ 361

Query: 301 WLDKVLTQMGSPSIRCSSVS 320
           WLDKVLTQMGSPSIRCSSVS
Sbjct: 362 WLDKVLTQMGSPSIRCSSVS 381


>gi|223029440 mothers against decapentaplegic homolog 3 isoform 2
           [Homo sapiens]
          Length = 320

 Score =  680 bits (1755), Expect = 0.0
 Identities = 320/320 (100%), Positives = 320/320 (100%)

Query: 1   MELCEFAFNMKKDEVCVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTN 60
           MELCEFAFNMKKDEVCVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTN
Sbjct: 1   MELCEFAFNMKKDEVCVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTN 60

Query: 61  FPAGIEPQSNIPETPPPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVT 120
           FPAGIEPQSNIPETPPPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVT
Sbjct: 61  FPAGIEPQSNIPETPPPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVT 120

Query: 121 YCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVEL 180
           YCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVEL
Sbjct: 121 YCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVEL 180

Query: 181 TRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNN 240
           TRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNN
Sbjct: 181 TRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNN 240

Query: 241 QEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQ 300
           QEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQ
Sbjct: 241 QEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQ 300

Query: 301 WLDKVLTQMGSPSIRCSSVS 320
           WLDKVLTQMGSPSIRCSSVS
Sbjct: 301 WLDKVLTQMGSPSIRCSSVS 320


>gi|51173730 Sma- and Mad-related protein 2 isoform 1 [Homo sapiens]
          Length = 467

 Score =  619 bits (1596), Expect = e-177
 Identities = 292/322 (90%), Positives = 307/322 (95%), Gaps = 2/322 (0%)

Query: 1   MELCEFAFNMKKDEVCVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTN 60
           +E CE+AFN+KKDEVCVNPYHYQRVETPVLPPVLVPRHTEI  E PPLDDY+HSIPENTN
Sbjct: 146 IENCEYAFNLKKDEVCVNPYHYQRVETPVLPPVLVPRHTEILTELPPLDDYTHSIPENTN 205

Query: 61  FPAGIEPQSN-IPETPPPGYLSEDGETSDHQMNHSMDAGSP-NLSPNPMSPAHNNLDLQP 118
           FPAGIEPQSN IPETPPPGY+SEDGETSD Q+N SMD GSP  LSP  +SP +++LDLQP
Sbjct: 206 FPAGIEPQSNYIPETPPPGYISEDGETSDQQLNQSMDTGSPAELSPTTLSPVNHSLDLQP 265

Query: 119 VTYCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAV 178
           VTY EPAFWCSI+YYELNQRVGETFHASQPS+TVDGFTDPSNSERFCLGLLSNVNRNA V
Sbjct: 266 VTYSEPAFWCSIAYYELNQRVGETFHASQPSLTVDGFTDPSNSERFCLGLLSNVNRNATV 325

Query: 179 ELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIF 238
           E+TRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIF
Sbjct: 326 EMTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIF 385

Query: 239 NNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGP 298
           NNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGP
Sbjct: 386 NNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGP 445

Query: 299 LQWLDKVLTQMGSPSIRCSSVS 320
           LQWLDKVLTQMGSPS+RCSS+S
Sbjct: 446 LQWLDKVLTQMGSPSVRCSSMS 467


>gi|5174511 Sma- and Mad-related protein 2 isoform 1 [Homo sapiens]
          Length = 467

 Score =  619 bits (1596), Expect = e-177
 Identities = 292/322 (90%), Positives = 307/322 (95%), Gaps = 2/322 (0%)

Query: 1   MELCEFAFNMKKDEVCVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTN 60
           +E CE+AFN+KKDEVCVNPYHYQRVETPVLPPVLVPRHTEI  E PPLDDY+HSIPENTN
Sbjct: 146 IENCEYAFNLKKDEVCVNPYHYQRVETPVLPPVLVPRHTEILTELPPLDDYTHSIPENTN 205

Query: 61  FPAGIEPQSN-IPETPPPGYLSEDGETSDHQMNHSMDAGSP-NLSPNPMSPAHNNLDLQP 118
           FPAGIEPQSN IPETPPPGY+SEDGETSD Q+N SMD GSP  LSP  +SP +++LDLQP
Sbjct: 206 FPAGIEPQSNYIPETPPPGYISEDGETSDQQLNQSMDTGSPAELSPTTLSPVNHSLDLQP 265

Query: 119 VTYCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAV 178
           VTY EPAFWCSI+YYELNQRVGETFHASQPS+TVDGFTDPSNSERFCLGLLSNVNRNA V
Sbjct: 266 VTYSEPAFWCSIAYYELNQRVGETFHASQPSLTVDGFTDPSNSERFCLGLLSNVNRNATV 325

Query: 179 ELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIF 238
           E+TRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIF
Sbjct: 326 EMTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIF 385

Query: 239 NNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGP 298
           NNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGP
Sbjct: 386 NNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGP 445

Query: 299 LQWLDKVLTQMGSPSIRCSSVS 320
           LQWLDKVLTQMGSPS+RCSS+S
Sbjct: 446 LQWLDKVLTQMGSPSVRCSSMS 467


>gi|209693426 Sma- and Mad-related protein 2 isoform 2 [Homo
           sapiens]
          Length = 437

 Score =  619 bits (1596), Expect = e-177
 Identities = 292/322 (90%), Positives = 307/322 (95%), Gaps = 2/322 (0%)

Query: 1   MELCEFAFNMKKDEVCVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTN 60
           +E CE+AFN+KKDEVCVNPYHYQRVETPVLPPVLVPRHTEI  E PPLDDY+HSIPENTN
Sbjct: 116 IENCEYAFNLKKDEVCVNPYHYQRVETPVLPPVLVPRHTEILTELPPLDDYTHSIPENTN 175

Query: 61  FPAGIEPQSN-IPETPPPGYLSEDGETSDHQMNHSMDAGSP-NLSPNPMSPAHNNLDLQP 118
           FPAGIEPQSN IPETPPPGY+SEDGETSD Q+N SMD GSP  LSP  +SP +++LDLQP
Sbjct: 176 FPAGIEPQSNYIPETPPPGYISEDGETSDQQLNQSMDTGSPAELSPTTLSPVNHSLDLQP 235

Query: 119 VTYCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAV 178
           VTY EPAFWCSI+YYELNQRVGETFHASQPS+TVDGFTDPSNSERFCLGLLSNVNRNA V
Sbjct: 236 VTYSEPAFWCSIAYYELNQRVGETFHASQPSLTVDGFTDPSNSERFCLGLLSNVNRNATV 295

Query: 179 ELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIF 238
           E+TRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIF
Sbjct: 296 EMTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIF 355

Query: 239 NNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGP 298
           NNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGP
Sbjct: 356 NNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGP 415

Query: 299 LQWLDKVLTQMGSPSIRCSSVS 320
           LQWLDKVLTQMGSPS+RCSS+S
Sbjct: 416 LQWLDKVLTQMGSPSVRCSSMS 437


>gi|223029444 mothers against decapentaplegic homolog 3 isoform 4
           [Homo sapiens]
          Length = 230

 Score =  487 bits (1253), Expect = e-138
 Identities = 230/230 (100%), Positives = 230/230 (100%)

Query: 91  MNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSM 150
           MNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSM
Sbjct: 1   MNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSM 60

Query: 151 TVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFV 210
           TVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFV
Sbjct: 61  TVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFV 120

Query: 211 QSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMS 270
           QSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMS
Sbjct: 121 QSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMS 180

Query: 271 FVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS 320
           FVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS
Sbjct: 181 FVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS 230


>gi|47778931 SMAD, mothers against DPP homolog 5 [Homo sapiens]
          Length = 465

 Score =  413 bits (1061), Expect = e-115
 Identities = 211/362 (58%), Positives = 248/362 (68%), Gaps = 45/362 (12%)

Query: 1   MELCEFAFNMKKDEVCVNPYHYQRVETPVLPPVLVPRHTE------IPAEFPPLDDYSHS 54
           +++CEF F  K+ EVC+NPYHY+RVE+PVLPPVLVPRH E      +  +F  L      
Sbjct: 107 LDICEFPFGSKQKEVCINPYHYKRVESPVLPPVLVPRHNEFNPQHSLLVQFRNLSHNEPH 166

Query: 55  IPENTNFPAGIEPQSNIP-----------------------------------ETPPPGY 79
           +P+N  FP      +N P                                   +TPPP Y
Sbjct: 167 MPQNATFPDSFHQPNNTPFPLSPNSPYPPSPASSTYPNSPASSGPGSPFQLPADTPPPAY 226

Query: 80  LSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRV 139
           +  D +      +  MD  S N+ P  M P+ ++ D+QPV Y EP  WCSI YYELN RV
Sbjct: 227 MPPDDQMGQDN-SQPMDT-SNNMIPQIM-PSISSRDVQPVAYEEPKHWCSIVYYELNNRV 283

Query: 140 GETFHASQPSMTVDGFTDPSNSE-RFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEV 198
           GE FHAS  S+ VDGFTDPSN++ RFCLGLLSNVNRN+ +E TRRHIG+GV LYY+GGEV
Sbjct: 284 GEAFHASSTSVLVDGFTDPSNNKSRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEV 343

Query: 199 FAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAV 258
           +AECLSDS+IFVQS NCN  +G+HP TVCKIP  C+LKIFNNQEFA LLAQSVN GFEAV
Sbjct: 344 YAECLSDSSIFVQSRNCNFHHGFHPTTVCKIPSSCSLKIFNNQEFAQLLAQSVNHGFEAV 403

Query: 259 YQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSS 318
           Y+LT+MCTIRMSFVKGWGAEY RQ VTSTPCWIE+HL+GPLQWLDKVLTQMGSP    SS
Sbjct: 404 YELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPLNPISS 463

Query: 319 VS 320
           VS
Sbjct: 464 VS 465


>gi|47778929 SMAD, mothers against DPP homolog 5 [Homo sapiens]
          Length = 465

 Score =  413 bits (1061), Expect = e-115
 Identities = 211/362 (58%), Positives = 248/362 (68%), Gaps = 45/362 (12%)

Query: 1   MELCEFAFNMKKDEVCVNPYHYQRVETPVLPPVLVPRHTE------IPAEFPPLDDYSHS 54
           +++CEF F  K+ EVC+NPYHY+RVE+PVLPPVLVPRH E      +  +F  L      
Sbjct: 107 LDICEFPFGSKQKEVCINPYHYKRVESPVLPPVLVPRHNEFNPQHSLLVQFRNLSHNEPH 166

Query: 55  IPENTNFPAGIEPQSNIP-----------------------------------ETPPPGY 79
           +P+N  FP      +N P                                   +TPPP Y
Sbjct: 167 MPQNATFPDSFHQPNNTPFPLSPNSPYPPSPASSTYPNSPASSGPGSPFQLPADTPPPAY 226

Query: 80  LSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRV 139
           +  D +      +  MD  S N+ P  M P+ ++ D+QPV Y EP  WCSI YYELN RV
Sbjct: 227 MPPDDQMGQDN-SQPMDT-SNNMIPQIM-PSISSRDVQPVAYEEPKHWCSIVYYELNNRV 283

Query: 140 GETFHASQPSMTVDGFTDPSNSE-RFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEV 198
           GE FHAS  S+ VDGFTDPSN++ RFCLGLLSNVNRN+ +E TRRHIG+GV LYY+GGEV
Sbjct: 284 GEAFHASSTSVLVDGFTDPSNNKSRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEV 343

Query: 199 FAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAV 258
           +AECLSDS+IFVQS NCN  +G+HP TVCKIP  C+LKIFNNQEFA LLAQSVN GFEAV
Sbjct: 344 YAECLSDSSIFVQSRNCNFHHGFHPTTVCKIPSSCSLKIFNNQEFAQLLAQSVNHGFEAV 403

Query: 259 YQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSS 318
           Y+LT+MCTIRMSFVKGWGAEY RQ VTSTPCWIE+HL+GPLQWLDKVLTQMGSP    SS
Sbjct: 404 YELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPLNPISS 463

Query: 319 VS 320
           VS
Sbjct: 464 VS 465


>gi|47778925 SMAD, mothers against DPP homolog 5 [Homo sapiens]
          Length = 465

 Score =  413 bits (1061), Expect = e-115
 Identities = 211/362 (58%), Positives = 248/362 (68%), Gaps = 45/362 (12%)

Query: 1   MELCEFAFNMKKDEVCVNPYHYQRVETPVLPPVLVPRHTE------IPAEFPPLDDYSHS 54
           +++CEF F  K+ EVC+NPYHY+RVE+PVLPPVLVPRH E      +  +F  L      
Sbjct: 107 LDICEFPFGSKQKEVCINPYHYKRVESPVLPPVLVPRHNEFNPQHSLLVQFRNLSHNEPH 166

Query: 55  IPENTNFPAGIEPQSNIP-----------------------------------ETPPPGY 79
           +P+N  FP      +N P                                   +TPPP Y
Sbjct: 167 MPQNATFPDSFHQPNNTPFPLSPNSPYPPSPASSTYPNSPASSGPGSPFQLPADTPPPAY 226

Query: 80  LSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRV 139
           +  D +      +  MD  S N+ P  M P+ ++ D+QPV Y EP  WCSI YYELN RV
Sbjct: 227 MPPDDQMGQDN-SQPMDT-SNNMIPQIM-PSISSRDVQPVAYEEPKHWCSIVYYELNNRV 283

Query: 140 GETFHASQPSMTVDGFTDPSNSE-RFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEV 198
           GE FHAS  S+ VDGFTDPSN++ RFCLGLLSNVNRN+ +E TRRHIG+GV LYY+GGEV
Sbjct: 284 GEAFHASSTSVLVDGFTDPSNNKSRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEV 343

Query: 199 FAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAV 258
           +AECLSDS+IFVQS NCN  +G+HP TVCKIP  C+LKIFNNQEFA LLAQSVN GFEAV
Sbjct: 344 YAECLSDSSIFVQSRNCNFHHGFHPTTVCKIPSSCSLKIFNNQEFAQLLAQSVNHGFEAV 403

Query: 259 YQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSS 318
           Y+LT+MCTIRMSFVKGWGAEY RQ VTSTPCWIE+HL+GPLQWLDKVLTQMGSP    SS
Sbjct: 404 YELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPLNPISS 463

Query: 319 VS 320
           VS
Sbjct: 464 VS 465


>gi|51173727 Sma- and Mad-related protein 1 [Homo sapiens]
          Length = 465

 Score =  409 bits (1052), Expect = e-114
 Identities = 215/365 (58%), Positives = 247/365 (67%), Gaps = 50/365 (13%)

Query: 1   MELCEFAFNMKKDEVCVNPYHYQRVETPVLPPVLVPRHTE------IPAEFPPLDDYSHS 54
           +E CEF F  K+ EVC+NPYHY+RVE+PVLPPVLVPRH+E      + A+F  L      
Sbjct: 106 LECCEFPFGSKQKEVCINPYHYKRVESPVLPPVLVPRHSEYNPQHSLLAQFRNLGQNEPH 165

Query: 55  IPENTNFPAGIE----------PQSNIP---------------------------ETPPP 77
           +P N  FP   +          P S+ P                           +TPPP
Sbjct: 166 MPLNATFPDSFQQPNSHPFPHSPNSSYPNSPGSSSSTYPHSPTSSDPGSPFQMPADTPPP 225

Query: 78  GYLS-EDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELN 136
            YL  ED  T D   +  MD    N+   P+    N  D+Q V Y EP  WCSI YYELN
Sbjct: 226 AYLPPEDPMTQDG--SQPMDT---NMMAPPLPSEINRGDVQAVAYEEPKHWCSIVYYELN 280

Query: 137 QRVGETFHASQPSMTVDGFTDPSNSE-RFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIG 195
            RVGE FHAS  S+ VDGFTDPSN++ RFCLGLLSNVNRN+ +E TRRHIG+GV LYY+G
Sbjct: 281 NRVGEAFHASSTSVLVDGFTDPSNNKNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVG 340

Query: 196 GEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGF 255
           GEV+AECLSDS+IFVQS NCN  +G+HP TVCKIP GC+LKIFNNQEFA LLAQSVN GF
Sbjct: 341 GEVYAECLSDSSIFVQSRNCNYHHGFHPTTVCKIPSGCSLKIFNNQEFAQLLAQSVNHGF 400

Query: 256 EAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIR 315
           E VY+LT+MCTIRMSFVKGWGAEY RQ VTSTPCWIE+HL+GPLQWLDKVLTQMGSP   
Sbjct: 401 ETVYELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNP 460

Query: 316 CSSVS 320
            SSVS
Sbjct: 461 ISSVS 465


>gi|5174509 Sma- and Mad-related protein 1 [Homo sapiens]
          Length = 465

 Score =  409 bits (1052), Expect = e-114
 Identities = 215/365 (58%), Positives = 247/365 (67%), Gaps = 50/365 (13%)

Query: 1   MELCEFAFNMKKDEVCVNPYHYQRVETPVLPPVLVPRHTE------IPAEFPPLDDYSHS 54
           +E CEF F  K+ EVC+NPYHY+RVE+PVLPPVLVPRH+E      + A+F  L      
Sbjct: 106 LECCEFPFGSKQKEVCINPYHYKRVESPVLPPVLVPRHSEYNPQHSLLAQFRNLGQNEPH 165

Query: 55  IPENTNFPAGIE----------PQSNIP---------------------------ETPPP 77
           +P N  FP   +          P S+ P                           +TPPP
Sbjct: 166 MPLNATFPDSFQQPNSHPFPHSPNSSYPNSPGSSSSTYPHSPTSSDPGSPFQMPADTPPP 225

Query: 78  GYLS-EDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELN 136
            YL  ED  T D   +  MD    N+   P+    N  D+Q V Y EP  WCSI YYELN
Sbjct: 226 AYLPPEDPMTQDG--SQPMDT---NMMAPPLPSEINRGDVQAVAYEEPKHWCSIVYYELN 280

Query: 137 QRVGETFHASQPSMTVDGFTDPSNSE-RFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIG 195
            RVGE FHAS  S+ VDGFTDPSN++ RFCLGLLSNVNRN+ +E TRRHIG+GV LYY+G
Sbjct: 281 NRVGEAFHASSTSVLVDGFTDPSNNKNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVG 340

Query: 196 GEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGF 255
           GEV+AECLSDS+IFVQS NCN  +G+HP TVCKIP GC+LKIFNNQEFA LLAQSVN GF
Sbjct: 341 GEVYAECLSDSSIFVQSRNCNYHHGFHPTTVCKIPSGCSLKIFNNQEFAQLLAQSVNHGF 400

Query: 256 EAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIR 315
           E VY+LT+MCTIRMSFVKGWGAEY RQ VTSTPCWIE+HL+GPLQWLDKVLTQMGSP   
Sbjct: 401 ETVYELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNP 460

Query: 316 CSSVS 320
            SSVS
Sbjct: 461 ISSVS 465


>gi|5174519 SMAD family member 9 isoform b [Homo sapiens]
          Length = 430

 Score =  404 bits (1038), Expect = e-113
 Identities = 203/330 (61%), Positives = 244/330 (73%), Gaps = 19/330 (5%)

Query: 1   MELCEFAFNMKKDEVCVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYS----HS-- 54
           +E CEF F  K+ EVC+NPYHY+RVETPVLPPVLVPRH+E   +   L  +     HS  
Sbjct: 110 LECCEFPFGSKQKEVCINPYHYRRVETPVLPPVLVPRHSEYNPQLSLLAKFRSASLHSEP 169

Query: 55  -IPENTNFPAGIE--PQSNIPETPPPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAH 111
            +P N  +P   +  P S +P +P   +       S    ++    GSP+    P SP +
Sbjct: 170 LMPHNATYPDSFQQPPCSALPPSPSHAF-----SQSPCTASYPHSPGSPS---EPESP-Y 220

Query: 112 NNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSE-RFCLGLLS 170
            + D +PV Y EP  WCS++YYELN RVGETF AS  S+ +DGFTDPSN+  RFCLGLLS
Sbjct: 221 QHSDFRPVCYEEPQHWCSVAYYELNNRVGETFQASSRSVLIDGFTDPSNNRNRFCLGLLS 280

Query: 171 NVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIP 230
           NVNRN+ +E TRRHIG+GV LYY+GGEV+AEC+SDS+IFVQS NCN ++G+HPATVCKIP
Sbjct: 281 NVNRNSTIENTRRHIGKGVHLYYVGGEVYAECVSDSSIFVQSRNCNYQHGFHPATVCKIP 340

Query: 231 PGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCW 290
            GC+LK+FNNQ FA LLAQSV+ GFE VY+LT+MCTIRMSFVKGWGAEY RQ VTSTPCW
Sbjct: 341 SGCSLKVFNNQLFAQLLAQSVHHGFEVVYELTKMCTIRMSFVKGWGAEYHRQDVTSTPCW 400

Query: 291 IELHLNGPLQWLDKVLTQMGSPSIRCSSVS 320
           IE+HL+GPLQWLDKVLTQMGSP    SSVS
Sbjct: 401 IEIHLHGPLQWLDKVLTQMGSPHNPISSVS 430


>gi|187828357 SMAD family member 9 isoform a [Homo sapiens]
          Length = 467

 Score =  397 bits (1020), Expect = e-111
 Identities = 207/359 (57%), Positives = 248/359 (69%), Gaps = 40/359 (11%)

Query: 1   MELCEFAFNMKKDEVCVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYS----HS-- 54
           +E CEF F  K+ EVC+NPYHY+RVETPVLPPVLVPRH+E   +   L  +     HS  
Sbjct: 110 LECCEFPFGSKQKEVCINPYHYRRVETPVLPPVLVPRHSEYNPQLSLLAKFRSASLHSEP 169

Query: 55  -IPENTNFPAGIE--PQSNIPETPP---------------PGYLSEDGETSDHQMN---- 92
            +P N  +P   +  P S +P +P                PG  SE      H ++    
Sbjct: 170 LMPHNATYPDSFQQPPCSALPPSPSHAFSQSPCTASYPHSPGSPSEPESPYQHSVDTPPL 229

Query: 93  --HSMDAGSPNLSPNPMSPAHN--------NLDLQPVTYCEPAFWCSISYYELNQRVGET 142
             H+ +A S   S  P+    +        N D +PV Y EP  WCS++YYELN RVGET
Sbjct: 230 PYHATEA-SETQSGQPVDATADRHVVLSIPNGDFRPVCYEEPQHWCSVAYYELNNRVGET 288

Query: 143 FHASQPSMTVDGFTDPSNSE-RFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAE 201
           F AS  S+ +DGFTDPSN+  RFCLGLLSNVNRN+ +E TRRHIG+GV LYY+GGEV+AE
Sbjct: 289 FQASSRSVLIDGFTDPSNNRNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAE 348

Query: 202 CLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQL 261
           C+SDS+IFVQS NCN ++G+HPATVCKIP GC+LK+FNNQ FA LLAQSV+ GFE VY+L
Sbjct: 349 CVSDSSIFVQSRNCNYQHGFHPATVCKIPSGCSLKVFNNQLFAQLLAQSVHHGFEVVYEL 408

Query: 262 TRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS 320
           T+MCTIRMSFVKGWGAEY RQ VTSTPCWIE+HL+GPLQWLDKVLTQMGSP    SSVS
Sbjct: 409 TKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS 467


>gi|4885457 mothers against decapentaplegic homolog 4 [Homo sapiens]
          Length = 552

 Score =  180 bits (456), Expect = 2e-45
 Identities = 139/433 (32%), Positives = 189/433 (43%), Gaps = 125/433 (28%)

Query: 1   MELCEFAFNMKKDEVCVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSI----- 55
           ++ C++AF++K D VCVNPYHY+RV +P +    +   +  P+     D+Y H       
Sbjct: 112 VKYCQYAFDLKCDSVCVNPYHYERVVSPGIDLSGLTLQSNAPSSMMVKDEYVHDFEGQPS 171

Query: 56  --------------PEN---------------------------------TNFPAGI--- 65
                         P N                                 T+ PA I   
Sbjct: 172 LSTEGHSIQTIQHPPSNRASTETYSTPALLAPSESNATSTANFPNIPVASTSQPASILGG 231

Query: 66  ---EPQSNIPETPPPGYLSEDGETSD----HQMNHSMDAGSPNLSPNPMSPAHNNLDLQ- 117
              E    I   P PG   ++G T      H  + +   GS      P  P H N  LQ 
Sbjct: 232 SHSEGLLQIASGPQPGQ-QQNGFTGQPATYHHNSTTTWTGSRTAPYTPNLPHHQNGHLQH 290

Query: 118 ---------------------PVTYCEPA--FWCSISYYELNQRVGETFH--ASQPSMTV 152
                                P     PA  +WCSI+Y+E++ +VGETF   +S P +TV
Sbjct: 291 HPPMPPHPGHYWPVHNELAFQPPISNHPAPEYWCSIAYFEMDVQVGETFKVPSSCPIVTV 350

Query: 153 DGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIG-GEVFAECLSDSAIFVQ 211
           DG+ DPS  +RFCLG LSNV+R  A+E  R HIG+GV+L   G G+V+  CLSD A+FVQ
Sbjct: 351 DGYVDPSGGDRFCLGQLSNVHRTEAIERARLHIGKGVQLECKGEGDVWVRCLSDHAVFVQ 410

Query: 212 SPNCNQRYGWHPA-TVCKIPPGCNLKIFN--------NQEFAALLAQSVNQGFE------ 256
           S   ++  G  P   V KI P   +K+F+         Q+ A   A +  Q         
Sbjct: 411 SYYLDREAGRAPGDAVHKIYPSAYIKVFDLRQCHRQMQQQAATAQAAAAAQAAAVAGNIP 470

Query: 257 --------------------AVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLN 296
                                V  L R+C +RMSFVKGWG +Y RQ++  TPCWIE+HL+
Sbjct: 471 GPGSVGGIAPAISLSAAAGIGVDDLRRLCILRMSFVKGWGPDYPRQSIKETPCWIEIHLH 530

Query: 297 GPLQWLDKVLTQM 309
             LQ LD+VL  M
Sbjct: 531 RALQLLDEVLHTM 543


>gi|92859871 SMAD family member 6 isoform 1 [Homo sapiens]
          Length = 496

 Score =  111 bits (277), Expect = 1e-24
 Identities = 87/286 (30%), Positives = 129/286 (45%), Gaps = 51/286 (17%)

Query: 15  VCVNPYHYQRVETPVLPPVLVPRHTEIPA--EFPPLDDYSHSIPENTNFPAGIEPQSNIP 72
           VC NPYH+ R+  P  PP   P ++ +    E+ PLD     + ++T      E  +++ 
Sbjct: 259 VCCNPYHFSRLCGPESPP---PPYSRLSPRDEYKPLD-----LSDSTLSYTETEATNSLI 310

Query: 73  ETPPPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISY 132
             P        GE SD  M           SP+   P+H               WCS++Y
Sbjct: 311 TAP--------GEFSDASM-----------SPDATKPSH---------------WCSVAY 336

Query: 133 YELNQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLY 192
           +E   RVG  +     ++++  F D      FCLG L+   R+ +V  TR  IG G+ L 
Sbjct: 337 WEHRTRVGRLYAVYDQAVSI--FYDLPQGSGFCLGQLNLEQRSESVRRTRSKIGFGILLS 394

Query: 193 YIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVN 252
                V+A    +  IFV SP  +   G     V K+PPG ++K+F + E + L      
Sbjct: 395 KEPDGVWAYNRGEHPIFVNSPTLDAP-GGRALVVRKVPPGYSIKVF-DFERSGLQHAPEP 452

Query: 253 QGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGP 298
              +  Y      ++R+SF KGWG  Y RQ +TS PCW+E+ LN P
Sbjct: 453 DAADGPYDPN---SVRISFAKGWGPCYSRQFITSCPCWLEILLNNP 495


>gi|218749837 SMAD family member 6 isoform 2 [Homo sapiens]
          Length = 235

 Score =  101 bits (252), Expect = 8e-22
 Identities = 74/235 (31%), Positives = 115/235 (48%), Gaps = 21/235 (8%)

Query: 73  ETPPPGY--LSEDGE-----TSDHQMNHSMDAGSPNL--SPNPMSPAHNNLDLQPVTYCE 123
           ++PPP Y  LS   E      SD  ++++    + +L  +P   S A  + D       +
Sbjct: 12  KSPPPPYSRLSPRDEYKPLDLSDSTLSYTETEATNSLITAPGEFSDASMSPDAT-----K 66

Query: 124 PAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELTRR 183
           P+ WCS++Y+E   RVG  +     ++++  F D      FCLG L+   R+ +V  TR 
Sbjct: 67  PSHWCSVAYWEHRTRVGRLYAVYDQAVSI--FYDLPQGSGFCLGQLNLEQRSESVRRTRS 124

Query: 184 HIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEF 243
            IG G+ L      V+A    +  IFV SP  +   G     V K+PPG ++K+F+ +  
Sbjct: 125 KIGFGILLSKEPDGVWAYNRGEHPIFVNSPTLDAP-GGRALVVRKVPPGYSIKVFDFERS 183

Query: 244 AALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGP 298
               A   +   +  Y      ++R+SF KGWG  Y RQ +TS PCW+E+ LN P
Sbjct: 184 GLQHAPEPDAA-DGPYDPN---SVRISFAKGWGPCYSRQFITSCPCWLEILLNNP 234


>gi|5174517 SMAD family member 7 [Homo sapiens]
          Length = 426

 Score = 96.7 bits (239), Expect = 2e-20
 Identities = 82/293 (27%), Positives = 133/293 (45%), Gaps = 48/293 (16%)

Query: 4   CEFAFNMKKDEVCVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPA 63
           CE    +  + VC NP+H  R+     PP   P ++  P +F                  
Sbjct: 180 CESYGKINPELVCCNPHHLSRLCELESPP---PPYSRYPMDF------------------ 218

Query: 64  GIEPQSNIPETPPPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCE 123
            ++P ++ P+  P        ET           G+  L+P  +S   + L L+P    +
Sbjct: 219 -LKPTADCPDAVP-----SSAET----------GGTNYLAPGGLS--DSQLLLEP---GD 257

Query: 124 PAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELTRR 183
            + WC ++Y+E   RVG  +   +PS+  D F D      FCLG L++ N++  V+  R 
Sbjct: 258 RSHWCVVAYWEEKTRVGRLYCVQEPSL--DIFYDLPQGNGFCLGQLNSDNKSQLVQKVRS 315

Query: 184 HIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEF 243
            IG G++L      V+    S   IF++S   +         V K+ PG ++K F+ ++ 
Sbjct: 316 KIGCGIQLTREVDGVWVYNRSSYPIFIKSATLDNPDS-RTLLVHKVFPGFSIKAFDYEKA 374

Query: 244 AALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLN 296
            +L  Q  N   E + Q     T+++SFVKGWG  Y RQ ++S PCW+E+  N
Sbjct: 375 YSL--QRPND-HEFMQQPWTGFTVQISFVKGWGQCYTRQFISSCPCWLEVIFN 424


>gi|146134388 YLP motif containing 1 [Homo sapiens]
          Length = 2146

 Score = 34.7 bits (78), Expect = 0.12
 Identities = 19/50 (38%), Positives = 22/50 (44%)

Query: 31  PPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETPPPGYL 80
           PP LVP   E P E PP+   S+  P  +  P    P S  P T    YL
Sbjct: 135 PPGLVPMELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPTSSQPYL 184



 Score = 29.6 bits (65), Expect = 3.7
 Identities = 23/103 (22%), Positives = 36/103 (34%), Gaps = 6/103 (5%)

Query: 23  QRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETPPPGYLSE 82
           Q++    +  VL P H   P   PP       +     +     P   +P  P P    +
Sbjct: 65  QQMHQKQMQCVLQPHHLPPPPLPPP------PVMPGGGYGDWQPPPPPMPPPPGPALSYQ 118

Query: 83  DGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPA 125
             +   HQM H    G P L P  +     +  + P +Y  P+
Sbjct: 119 KQQQYKHQMLHHQRDGPPGLVPMELESPPESPPVPPGSYMPPS 161


>gi|239757414 PREDICTED: hypothetical protein XP_002345432 [Homo
           sapiens]
          Length = 176

 Score = 33.9 bits (76), Expect = 0.20
 Identities = 27/94 (28%), Positives = 37/94 (39%), Gaps = 10/94 (10%)

Query: 16  CVNPYHYQRVETPVLPPVLVPR---HTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIP 72
           C  P+  +R  T  LPP L P    H+  P    P    +   P+    PA + PQ   P
Sbjct: 75  CTQPHRRRRRGTRRLPPALTPAGPYHSARPGGGGPCQGSARFSPD----PAAVRPQ---P 127

Query: 73  ETPPPGYLSEDGETSDHQMNHSMDAGSPNLSPNP 106
             P P   S      D +   ++  G+P  SP P
Sbjct: 128 RGPQPDSGSARQVPPDSRGAQALHRGAPLASPAP 161


>gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [Homo
            sapiens]
          Length = 1636

 Score = 32.7 bits (73), Expect = 0.44
 Identities = 28/99 (28%), Positives = 39/99 (39%), Gaps = 15/99 (15%)

Query: 26   ETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSN--IPETPPPGYLSED 83
            E P LPP  +P  T IP+  PP        P ++  P   +P+    +PE P  G  S  
Sbjct: 1525 EPPGLPPASLPESTPIPSSSPP--------PLSSPLPEAPQPKEEPPVPEAPSSGPPSSS 1576

Query: 84   GE-----TSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQ 117
             E     T +     S   G   +S +    AHN   L+
Sbjct: 1577 LELLASLTPEAFSLDSSLRGKQRMSKHNFLQAHNGQGLR 1615



 Score = 28.5 bits (62), Expect = 8.3
 Identities = 26/93 (27%), Positives = 30/93 (32%), Gaps = 14/93 (15%)

Query: 42   PAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETPPPGYLSE----------DGETSDHQM 91
            P + P    + H  P     P  + PQS  P  P PG L +           G   D   
Sbjct: 971  PPQQPLPLQHPHLFPPQA--PGLLPPQSPYPYAPQPGVLGQPPPPLHTQLYPGPAQDPLP 1028

Query: 92   NHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEP 124
             HS     P  SP P  P H  L   P     P
Sbjct: 1029 AHS--GALPFPSPGPPQPPHPPLAYGPAPSTRP 1059


>gi|217416343 fibrosin-like 1 [Homo sapiens]
          Length = 1045

 Score = 32.3 bits (72), Expect = 0.58
 Identities = 25/103 (24%), Positives = 42/103 (40%), Gaps = 13/103 (12%)

Query: 19  PYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYS-------HSIPENTNFPAGIEPQSNI 71
           P+ +     P  P  L+P H  +PA       +S       H +  +++ P G+    ++
Sbjct: 294 PHRHTPQPPPPQPRGLLPTH--VPASLGAFAGHSQAAANGLHGLSRSSSAPLGLGKHVSL 351

Query: 72  PETPPPGYLSEDG----ETSDHQMNHSMDAGSPNLSPNPMSPA 110
               P  +LS         + HQ++ +M A  P L P P  PA
Sbjct: 352 SPHGPGPHLSTSHLALRSQAQHQLHAAMFAAPPTLPPPPALPA 394


>gi|125858485 hypothetical protein LOC80209 isoform 2 [Homo sapiens]
          Length = 922

 Score = 32.0 bits (71), Expect = 0.75
 Identities = 22/90 (24%), Positives = 32/90 (35%), Gaps = 13/90 (14%)

Query: 31  PPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETPPPGYLSEDGETSDHQ 90
           PP     H  +P   PP   ++   P   N  AG+ P +N+   PPP Y      T +  
Sbjct: 167 PPSTYNPHKPVPYPIPPCRPHATIAPSAYN-NAGLVPLANVIAPPPPPYTPNPVGTENED 225

Query: 91  MNHSMDAGSPNLSPNPMSPAHNNLDLQPVT 120
           ++            NP  P  N     P +
Sbjct: 226 LS------------NPSKPIQNQTFSTPAS 243


>gi|125656155 hypothetical protein LOC80209 isoform 1 [Homo sapiens]
          Length = 944

 Score = 32.0 bits (71), Expect = 0.75
 Identities = 22/90 (24%), Positives = 32/90 (35%), Gaps = 13/90 (14%)

Query: 31  PPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETPPPGYLSEDGETSDHQ 90
           PP     H  +P   PP   ++   P   N  AG+ P +N+   PPP Y      T +  
Sbjct: 189 PPSTYNPHKPVPYPIPPCRPHATIAPSAYN-NAGLVPLANVIAPPPPPYTPNPVGTENED 247

Query: 91  MNHSMDAGSPNLSPNPMSPAHNNLDLQPVT 120
           ++            NP  P  N     P +
Sbjct: 248 LS------------NPSKPIQNQTFSTPAS 265


>gi|157168329 formin 1 [Homo sapiens]
          Length = 1196

 Score = 31.2 bits (69), Expect = 1.3
 Identities = 34/136 (25%), Positives = 45/136 (33%), Gaps = 24/136 (17%)

Query: 28  PVLPPVLVPRHTEIPAEFPPLDDYSHS-IPENTNFPAGIEPQSNIPETPPPGYLSEDGET 86
           P  PP L P  +  P   PP     +S  P N   P    P   +   PPPG     G +
Sbjct: 684 PPPPPPLPPPSSAGPPPPPPPPPLPNSPAPPNPGGPPPAPPPPGLAPPPPPGLFFGLGSS 743

Query: 87  SDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHAS 146
           S               S  P  PA     ++P    +P +W  I   + +Q    T    
Sbjct: 744 S---------------SQCPRKPA-----IEPSCPMKPLYWTRIQISDRSQNATPTL--- 780

Query: 147 QPSMTVDGFTDPSNSE 162
             S+      DPS  E
Sbjct: 781 WDSLEEPDIRDPSEFE 796


>gi|154689780 son of sevenless homolog 2 [Homo sapiens]
          Length = 1332

 Score = 31.2 bits (69), Expect = 1.3
 Identities = 24/93 (25%), Positives = 39/93 (41%), Gaps = 10/93 (10%)

Query: 31   PPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETPPPGYLSEDGETSDHQ 90
            PP + PR    P   P +   + +     + P    P+  +P+TPPP  L       +H 
Sbjct: 1172 PPAIPPRQPPPPKVKPRVPVPTGAFDGPLHSPPPPPPRDPLPDTPPPVPL----RPPEHF 1227

Query: 91   MNHSMDAGSPNLSPNPMSPAHNNLD-LQPVTYC 122
            +N        NL P P+   H + D L+ ++ C
Sbjct: 1228 INCPF-----NLQPPPLGHLHRDSDWLRDISTC 1255


>gi|34452173 integrin alpha X precursor [Homo sapiens]
          Length = 1163

 Score = 31.2 bits (69), Expect = 1.3
 Identities = 13/39 (33%), Positives = 21/39 (53%)

Query: 280  RRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSS 318
            +R    S   W+ + LN    W+D  ++   +PS+RCSS
Sbjct: 962  QRDLPVSINFWVPVELNQEAVWMDVEVSHPQNPSLRCSS 1000


>gi|58219024 hypothetical protein LOC352999 [Homo sapiens]
          Length = 330

 Score = 30.8 bits (68), Expect = 1.7
 Identities = 13/36 (36%), Positives = 22/36 (61%)

Query: 60 NFPAGIEPQSNIPETPPPGYLSEDGETSDHQMNHSM 95
          +F A +   SN+ ET PP +    G+ SD+++ +SM
Sbjct: 14 SFSASLAGTSNLSETEPPLWKESPGQLSDYRVENSM 49


>gi|11276067 snail 2 [Homo sapiens]
          Length = 268

 Score = 30.4 bits (67), Expect = 2.2
 Identities = 23/103 (22%), Positives = 42/103 (40%), Gaps = 14/103 (13%)

Query: 15  VCVNPYHYQRVETPVLP-PVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPE 73
           V ++PY Y+    PV+P P ++         + P+  ++ + P +   P G+ P S    
Sbjct: 27  VIISPYLYESYSMPVIPQPEILS-----SGAYSPITVWTTAAPFHAQLPNGLSPLSGYSS 81

Query: 74  -----TPPPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAH 111
                +PPP     D  + DH  + S  +       + +S  H
Sbjct: 82  SLGRVSPPP---PSDTSSKDHSGSESPISDEEERLQSKLSDPH 121


>gi|110611908 mitogen-activated protein kinase kinase kinase kinase
           1 isoform 1 [Homo sapiens]
          Length = 821

 Score = 30.4 bits (67), Expect = 2.2
 Identities = 24/83 (28%), Positives = 34/83 (40%), Gaps = 6/83 (7%)

Query: 49  DDYSH-SIP---ENTNFPAGIEPQSNIPETPPPGYLSEDGETSDHQMNHSMDAGSPNLSP 104
           DDY    IP   E+T  P   +P+   P    PG + +DG+ S   +        PN SP
Sbjct: 379 DDYDDVDIPTPAEDTPPPLPPKPKFRSPSDEGPGSMGDDGQLSPGVLVRCASGPPPN-SP 437

Query: 105 NPMSPAHNNLDLQPVTYCEPAFW 127
            P  P  +        + EP+ W
Sbjct: 438 RP-GPPPSTSSPHLTAHSEPSLW 459


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.134    0.431 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,052,591
Number of Sequences: 37866
Number of extensions: 807570
Number of successful extensions: 2313
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 23
Number of HSP's successfully gapped in prelim test: 52
Number of HSP's that attempted gapping in prelim test: 2231
Number of HSP's gapped (non-prelim): 100
length of query: 320
length of database: 18,247,518
effective HSP length: 102
effective length of query: 218
effective length of database: 14,385,186
effective search space: 3135970548
effective search space used: 3135970548
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.