Guide to the Human Genome
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Name: MAP4K1 Sequence: fasta or formatted (821aa) NCBI GI: 110611908
Description:

mitogen-activated protein kinase kinase kinase kinase 1 isoform 1

Referenced in:

MAP Kinase Pathways

Other entries for this name:
alt prot [833aa] mitogen-activated protein kinase kinase kinase kinase 1 isoform 2
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             6.0         49           2
 C cysteine            1.9         16           2
 D aspartate           5.4         44           3
 E glutamate           5.4         44           2
 F phenylalanine       2.7         22           1
 G glycine             7.6         62           3
 H histidine           2.7         22           1
 I isoleucine          4.4         36           1
 K lysine              5.4         44           2
 L leucine            12.1         99           3
 M methionine          2.6         21           1
 N asparagine          2.4         20           2
 P proline             9.5         78           3
 Q glutamine           3.7         30           1
 R arginine            6.1         50           2
 S serine              7.8         64           3
 T threonine           5.0         41           2
 V valine              6.3         52           3
 W tryptophan          1.5         12           1
 Y tyrosine            1.8         15           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   mitogen-activated protein kinase kinase kinase kina... 
MAP4K1                0.973   mitogen-activated protein kinase kinase kinase kinase...
MAP4K5                0.432   mitogen-activated protein kinase kinase kinase kinas...
MAP4K5                0.432   mitogen-activated protein kinase kinase kinase kinas...
MAP4K3                0.421   mitogen-activated protein kinase kinase kinase kinas...
MAP4K2                0.376   mitogen-activated protein kinase kinase kinase kinas...
STK4                  0.136   serine/threonine kinase 4 
TNIK                  0.133   TRAF2 and NCK interacting kinase isoform 8 
TNIK                  0.133   TRAF2 and NCK interacting kinase isoform 7 
TNIK                  0.133   TRAF2 and NCK interacting kinase isoform 6 
TNIK                  0.133   TRAF2 and NCK interacting kinase isoform 5 
TNIK                  0.133   TRAF2 and NCK interacting kinase isoform 4 
TNIK                  0.133   TRAF2 and NCK interacting kinase isoform 3 
TNIK                  0.133   TRAF2 and NCK interacting kinase isoform 2 
TNIK                  0.133   TRAF2 and NCK interacting kinase isoform 1 
MST4                  0.133   serine/threonine protein kinase MST4 isoform 1 [Homo...
STK24                 0.132   serine/threonine kinase 24 isoform b 
STK24                 0.132   serine/threonine kinase 24 isoform a 
MINK1                 0.131   misshapen/NIK-related kinase isoform 4 
MINK1                 0.131   misshapen/NIK-related kinase isoform 2 
MINK1                 0.131   misshapen/NIK-related kinase isoform 3 
MINK1                 0.131   misshapen/NIK-related kinase isoform 1 
STK25                 0.131   serine/threonine kinase 25 
STK3                  0.131   serine/threonine kinase 3 
MAP4K4                0.130   mitogen-activated protein kinase kinase kinase kinas...
MAP4K4                0.130   mitogen-activated protein kinase kinase kinase kinas...
MAP4K4                0.130   mitogen-activated protein kinase kinase kinase kinas...
STK10                 0.128   serine/threonine kinase 10 
MYO3A                 0.117   myosin IIIA 
SLK                   0.116   serine/threonine kinase 2 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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