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Search of human proteins with 222831595
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|222831595 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 [Homo
sapiens]
(1712 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|222831595 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 [Homo sap... 3453 0.0
gi|149274648 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like [Hom... 2233 0.0
gi|193211480 superkiller viralicidic activity 2-like 2 [Homo sap... 80 1e-14
gi|67782311 superkiller viralicidic activity 2-like homolog [Hom... 80 2e-14
gi|139394648 DNA polymerase theta [Homo sapiens] 76 3e-13
gi|110556640 DNA helicase HEL308 [Homo sapiens] 66 3e-10
gi|40217847 activating signal cointegrator 1 complex subunit 3-l... 65 4e-10
gi|169218225 PREDICTED: similar to U5 snRNP-specific 200kD prote... 65 6e-10
gi|76880486 activating signal cointegrator 1 complex subunit 3 i... 60 2e-08
gi|130484567 HFM1 protein [Homo sapiens] 57 2e-07
gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo... 42 0.004
gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo... 42 0.004
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 42 0.005
gi|30581135 structural maintenance of chromosomes 1A [Homo sapiens] 42 0.005
gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo ... 42 0.005
gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo... 39 0.033
gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [... 39 0.033
gi|116812616 RecQ protein-like 4 [Homo sapiens] 39 0.057
gi|195976782 Paf1/RNA polymerase II complex component [Homo sapi... 37 0.22
gi|14591902 RecQ protein-like [Homo sapiens] 36 0.28
gi|14591904 RecQ protein-like [Homo sapiens] 36 0.28
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s... 36 0.37
gi|21735569 claspin [Homo sapiens] 36 0.37
gi|67782362 DEAH (Asp-Glu-Ala-His) box polypeptide 29 [Homo sapi... 36 0.37
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 36 0.37
gi|13129006 nucleolar protein GU2 [Homo sapiens] 36 0.37
gi|40807445 protein regulator of cytokinesis 1 isoform 3 [Homo s... 35 0.48
gi|40807443 protein regulator of cytokinesis 1 isoform 2 [Homo s... 35 0.48
gi|4506039 protein regulator of cytokinesis 1 isoform 1 [Homo sa... 35 0.48
gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo sapi... 35 0.63
>gi|222831595 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 [Homo sapiens]
Length = 1712
Score = 3453 bits (8953), Expect = 0.0
Identities = 1712/1712 (100%), Positives = 1712/1712 (100%)
Query: 1 MERNVLTTFSQEMSQLILNEMPKAEYSSLFNDFVESEFFLIDGDSLLITCICEISFKPGQ 60
MERNVLTTFSQEMSQLILNEMPKAEYSSLFNDFVESEFFLIDGDSLLITCICEISFKPGQ
Sbjct: 1 MERNVLTTFSQEMSQLILNEMPKAEYSSLFNDFVESEFFLIDGDSLLITCICEISFKPGQ 60
Query: 61 NLHFFYLVERYLVDLISKGGQFTIVFFKDAEYAYFNFPELLSLRTALILHLQKNTTIDVR 120
NLHFFYLVERYLVDLISKGGQFTIVFFKDAEYAYFNFPELLSLRTALILHLQKNTTIDVR
Sbjct: 61 NLHFFYLVERYLVDLISKGGQFTIVFFKDAEYAYFNFPELLSLRTALILHLQKNTTIDVR 120
Query: 121 TTFSRCLSKEWGSFLEESYPYFLIVADEGLNDLQTQLFNFLIIHSWARKVNVVLSSGQES 180
TTFSRCLSKEWGSFLEESYPYFLIVADEGLNDLQTQLFNFLIIHSWARKVNVVLSSGQES
Sbjct: 121 TTFSRCLSKEWGSFLEESYPYFLIVADEGLNDLQTQLFNFLIIHSWARKVNVVLSSGQES 180
Query: 181 DVLCLYAYLLPSMYRHQIFSWKNKQNIKDAYTTLLNQLERFKLSALAPLFGSLKWNNITE 240
DVLCLYAYLLPSMYRHQIFSWKNKQNIKDAYTTLLNQLERFKLSALAPLFGSLKWNNITE
Sbjct: 181 DVLCLYAYLLPSMYRHQIFSWKNKQNIKDAYTTLLNQLERFKLSALAPLFGSLKWNNITE 240
Query: 241 EAHKTVSLLTQVWPEGSDIRRVFCVTSCSLSLRMYHRFLGNREPSSGQETEIQQVNSNCL 300
EAHKTVSLLTQVWPEGSDIRRVFCVTSCSLSLRMYHRFLGNREPSSGQETEIQQVNSNCL
Sbjct: 241 EAHKTVSLLTQVWPEGSDIRRVFCVTSCSLSLRMYHRFLGNREPSSGQETEIQQVNSNCL 300
Query: 301 TLQEMEDLCKLHCLTVVFLLHLPLSQRACARVITSHWAEDMKPLLQMKKWCEYFILRNIH 360
TLQEMEDLCKLHCLTVVFLLHLPLSQRACARVITSHWAEDMKPLLQMKKWCEYFILRNIH
Sbjct: 301 TLQEMEDLCKLHCLTVVFLLHLPLSQRACARVITSHWAEDMKPLLQMKKWCEYFILRNIH 360
Query: 361 TFEFWNLNLIHLSDLNDELLLKNIAFYYENENVKGLHLNLGDTIMKDYEYLWNTVSKLVR 420
TFEFWNLNLIHLSDLNDELLLKNIAFYYENENVKGLHLNLGDTIMKDYEYLWNTVSKLVR
Sbjct: 361 TFEFWNLNLIHLSDLNDELLLKNIAFYYENENVKGLHLNLGDTIMKDYEYLWNTVSKLVR 420
Query: 421 DFEVGQPFPLRTTKVCFLEKKPSPIKDSSNEMVPNLGFIPTSSFVVDKFAGDILKDLPFL 480
DFEVGQPFPLRTTKVCFLEKKPSPIKDSSNEMVPNLGFIPTSSFVVDKFAGDILKDLPFL
Sbjct: 421 DFEVGQPFPLRTTKVCFLEKKPSPIKDSSNEMVPNLGFIPTSSFVVDKFAGDILKDLPFL 480
Query: 481 KSDDPIVTSLVKQKEFDELVHWHSHKPLSDDYDRSRCQFDEKSRDPRVLRSVQKYHVFQR 540
KSDDPIVTSLVKQKEFDELVHWHSHKPLSDDYDRSRCQFDEKSRDPRVLRSVQKYHVFQR
Sbjct: 481 KSDDPIVTSLVKQKEFDELVHWHSHKPLSDDYDRSRCQFDEKSRDPRVLRSVQKYHVFQR 540
Query: 541 FYGNSLETVSSKIIVTQTIKSKKDFSGPKSKKAHETKAEIIARENKKRLFAREEQKEEQK 600
FYGNSLETVSSKIIVTQTIKSKKDFSGPKSKKAHETKAEIIARENKKRLFAREEQKEEQK
Sbjct: 541 FYGNSLETVSSKIIVTQTIKSKKDFSGPKSKKAHETKAEIIARENKKRLFAREEQKEEQK 600
Query: 601 WNALSFSIEEQLKENLHSGIKSLEDFLKSCKSSCVKLQVEMVGLTACLKAWKEHCRSEEG 660
WNALSFSIEEQLKENLHSGIKSLEDFLKSCKSSCVKLQVEMVGLTACLKAWKEHCRSEEG
Sbjct: 601 WNALSFSIEEQLKENLHSGIKSLEDFLKSCKSSCVKLQVEMVGLTACLKAWKEHCRSEEG 660
Query: 661 KTTKDLSIAVQVMKRIHSLMEKYSELLQEDDRQLIARCLKYLGFDELASSLHPAQDAEND 720
KTTKDLSIAVQVMKRIHSLMEKYSELLQEDDRQLIARCLKYLGFDELASSLHPAQDAEND
Sbjct: 661 KTTKDLSIAVQVMKRIHSLMEKYSELLQEDDRQLIARCLKYLGFDELASSLHPAQDAEND 720
Query: 721 VKVKKRNKYSVGIGPARFQLQYMGHYLIRDERKDPDPRVQDFIPDTWQRELLDVVDKNES 780
VKVKKRNKYSVGIGPARFQLQYMGHYLIRDERKDPDPRVQDFIPDTWQRELLDVVDKNES
Sbjct: 721 VKVKKRNKYSVGIGPARFQLQYMGHYLIRDERKDPDPRVQDFIPDTWQRELLDVVDKNES 780
Query: 781 AVIVAPTSSGKTYASYYCMEKVLKESDDGVVVYVAPTKALVNQVAATVQNRFTKNLPSGE 840
AVIVAPTSSGKTYASYYCMEKVLKESDDGVVVYVAPTKALVNQVAATVQNRFTKNLPSGE
Sbjct: 781 AVIVAPTSSGKTYASYYCMEKVLKESDDGVVVYVAPTKALVNQVAATVQNRFTKNLPSGE 840
Query: 841 VLCGVFTREYRHDALNCQVLITVPACFEILLLAPHRQNWVKKIRYVIFDEVHCLGGEIGA 900
VLCGVFTREYRHDALNCQVLITVPACFEILLLAPHRQNWVKKIRYVIFDEVHCLGGEIGA
Sbjct: 841 VLCGVFTREYRHDALNCQVLITVPACFEILLLAPHRQNWVKKIRYVIFDEVHCLGGEIGA 900
Query: 901 EIWEHLLVMIRCPFLALSATISNPEHLTEWLQSVKWYWKQEDKIIENNTASKRHVGRQAG 960
EIWEHLLVMIRCPFLALSATISNPEHLTEWLQSVKWYWKQEDKIIENNTASKRHVGRQAG
Sbjct: 901 EIWEHLLVMIRCPFLALSATISNPEHLTEWLQSVKWYWKQEDKIIENNTASKRHVGRQAG 960
Query: 961 FPKDYLQVKQSYKVRLVLYGERYNDLEKHVCSIKHGDIHFDHFHPCAALTTDHIERYGFP 1020
FPKDYLQVKQSYKVRLVLYGERYNDLEKHVCSIKHGDIHFDHFHPCAALTTDHIERYGFP
Sbjct: 961 FPKDYLQVKQSYKVRLVLYGERYNDLEKHVCSIKHGDIHFDHFHPCAALTTDHIERYGFP 1020
Query: 1021 PDLTLSPRESIQLYDAMFQIWKSWPRAQELCPENFIHFNNKLVIKKMDARKYEESLKAEL 1080
PDLTLSPRESIQLYDAMFQIWKSWPRAQELCPENFIHFNNKLVIKKMDARKYEESLKAEL
Sbjct: 1021 PDLTLSPRESIQLYDAMFQIWKSWPRAQELCPENFIHFNNKLVIKKMDARKYEESLKAEL 1080
Query: 1081 TSWIKNGNVEQARMVLQNLSPEADLSPENMITMFPLLVEKLRKMEKLPALFFLFKLGAVE 1140
TSWIKNGNVEQARMVLQNLSPEADLSPENMITMFPLLVEKLRKMEKLPALFFLFKLGAVE
Sbjct: 1081 TSWIKNGNVEQARMVLQNLSPEADLSPENMITMFPLLVEKLRKMEKLPALFFLFKLGAVE 1140
Query: 1141 NAAESVSTFLKKKQETKRPPKADKEAHVMANKLRKVKKSIEKQKIIDEKSQKKTRNVDQS 1200
NAAESVSTFLKKKQETKRPPKADKEAHVMANKLRKVKKSIEKQKIIDEKSQKKTRNVDQS
Sbjct: 1141 NAAESVSTFLKKKQETKRPPKADKEAHVMANKLRKVKKSIEKQKIIDEKSQKKTRNVDQS 1200
Query: 1201 LIHEAEHDNLVKCLEKNLEIPQDCTYADQKAVDTETLQKVFGRVKFERKGEELKALAERG 1260
LIHEAEHDNLVKCLEKNLEIPQDCTYADQKAVDTETLQKVFGRVKFERKGEELKALAERG
Sbjct: 1201 LIHEAEHDNLVKCLEKNLEIPQDCTYADQKAVDTETLQKVFGRVKFERKGEELKALAERG 1260
Query: 1261 IGYHHSAMSFKEKQLVEILFRKGYLRVVTATGTLALGVNMPCKSVVFAQNSVYLDALNYR 1320
IGYHHSAMSFKEKQLVEILFRKGYLRVVTATGTLALGVNMPCKSVVFAQNSVYLDALNYR
Sbjct: 1261 IGYHHSAMSFKEKQLVEILFRKGYLRVVTATGTLALGVNMPCKSVVFAQNSVYLDALNYR 1320
Query: 1321 QMSGRAGRRGQDLMGDVYFFDIPFPKIGKLIKSNVPELRGHFPLSITLVLRLMLLASKGD 1380
QMSGRAGRRGQDLMGDVYFFDIPFPKIGKLIKSNVPELRGHFPLSITLVLRLMLLASKGD
Sbjct: 1321 QMSGRAGRRGQDLMGDVYFFDIPFPKIGKLIKSNVPELRGHFPLSITLVLRLMLLASKGD 1380
Query: 1381 DPEDAKAKVLSVLKHSLLSFKQPRVMDMLKLYFLFSLQFLVKEGYLDQEGNPMGFAGLVS 1440
DPEDAKAKVLSVLKHSLLSFKQPRVMDMLKLYFLFSLQFLVKEGYLDQEGNPMGFAGLVS
Sbjct: 1381 DPEDAKAKVLSVLKHSLLSFKQPRVMDMLKLYFLFSLQFLVKEGYLDQEGNPMGFAGLVS 1440
Query: 1441 HLHYHEPSNLVFVSFLVNGLFHDLCQPTRKGSKHFSQDVMEKLVLVLAHLFGRRYFPPKF 1500
HLHYHEPSNLVFVSFLVNGLFHDLCQPTRKGSKHFSQDVMEKLVLVLAHLFGRRYFPPKF
Sbjct: 1441 HLHYHEPSNLVFVSFLVNGLFHDLCQPTRKGSKHFSQDVMEKLVLVLAHLFGRRYFPPKF 1500
Query: 1501 QDAHFEFYQSKVFLDDLPEDFSDALDEYNMKIMEDFTTFLRIVSKLADMNQEYQLPLSKI 1560
QDAHFEFYQSKVFLDDLPEDFSDALDEYNMKIMEDFTTFLRIVSKLADMNQEYQLPLSKI
Sbjct: 1501 QDAHFEFYQSKVFLDDLPEDFSDALDEYNMKIMEDFTTFLRIVSKLADMNQEYQLPLSKI 1560
Query: 1561 KFTGKECEDSQLVSHLMSCKEGRVAISPFVCLSGNFDDDLLRLETPNHVTLGTIGVNRSQ 1620
KFTGKECEDSQLVSHLMSCKEGRVAISPFVCLSGNFDDDLLRLETPNHVTLGTIGVNRSQ
Sbjct: 1561 KFTGKECEDSQLVSHLMSCKEGRVAISPFVCLSGNFDDDLLRLETPNHVTLGTIGVNRSQ 1620
Query: 1621 APVLLSQKFDNRGRKMSLNAYALDFYKHGSLIGLVQDNRMNEGDAYYLLKDFALTIKSIS 1680
APVLLSQKFDNRGRKMSLNAYALDFYKHGSLIGLVQDNRMNEGDAYYLLKDFALTIKSIS
Sbjct: 1621 APVLLSQKFDNRGRKMSLNAYALDFYKHGSLIGLVQDNRMNEGDAYYLLKDFALTIKSIS 1680
Query: 1681 VSLRELCENEDDNVVLAFEQLSTTFWEKLNKV 1712
VSLRELCENEDDNVVLAFEQLSTTFWEKLNKV
Sbjct: 1681 VSLRELCENEDDNVVLAFEQLSTTFWEKLNKV 1712
>gi|149274648 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like [Homo
sapiens]
Length = 1706
Score = 2233 bits (5786), Expect = 0.0
Identities = 1130/1713 (65%), Positives = 1360/1713 (79%), Gaps = 34/1713 (1%)
Query: 9 FSQEMSQLILNEMPKAEYSSLFNDFVESEFFLIDGDSLLITCICEISFKPGQNLHFFYLV 68
F +EM+QLILNEMPKA YSS+ NDFVES FF+IDGDSLL+TC+ SFK GQNLHFFYLV
Sbjct: 9 FFREMTQLILNEMPKAGYSSILNDFVESNFFVIDGDSLLVTCLGVKSFKWGQNLHFFYLV 68
Query: 69 ERYLVDLISKGGQFTIVFFKDAEYAYFNFPELLSLRTALILHLQKNTTIDVRTTFSRCLS 128
E YLVDL+S GGQFTIVFFKDAEYAYF+FPELLSLRTALILHLQ NT IDV+T FS CLS
Sbjct: 69 ECYLVDLLSNGGQFTIVFFKDAEYAYFDFPELLSLRTALILHLQHNTNIDVQTEFSGCLS 128
Query: 129 KEWGSFLEESYPYFLIVADEGLNDLQTQLFNFLIIHSWARKVNVVLSSGQESDVLCLYAY 188
++W FLE+ YPYFLIV++EGL+DLQT LFNFLIIHSW KVNVVLSSG ESD L YAY
Sbjct: 129 QDWKLFLEQHYPYFLIVSEEGLSDLQTYLFNFLIIHSWGMKVNVVLSSGHESDTLRFYAY 188
Query: 189 LLPSMYRHQIFSWKNKQNIKDAYTTLLNQLERFKLSALAPLFGSLKWNNITEEAHKTVSL 248
+ S R+Q FS +N+ I+ AY +L+ LE ++ LA F LKWN++ EEA++T+ L
Sbjct: 189 TMESTDRNQTFSKENETVIQSAYKSLIQHLEEIRVLVLATHFEHLKWNDMMEEAYQTLFL 248
Query: 249 LTQVWPEGSDIRRVFCVTSCSLSLRMYHRFLGNREPSSGQETEIQQVNSNCLTLQEMEDL 308
L +W EGSDI+RV CVTSCSLSLRMYHR L V+SNCL+LQE+ED
Sbjct: 249 LQHLWSEGSDIQRVLCVTSCSLSLRMYHRVL---------------VHSNCLSLQEVEDF 293
Query: 309 CKLHCLTVVFLLHLPLSQRACARVITSHWAEDMKPLLQMKKWCEYFILRNIHTFEFWNLN 368
C+L CL V F LHLPLSQRAC+RVIT W + L+M KWCEYFIL N++ F WNLN
Sbjct: 294 CRLRCLCVAFQLHLPLSQRACSRVITCSWIRNSDSFLKMNKWCEYFILSNLNVFGCWNLN 353
Query: 369 LIHLSDLNDELLLKNIAFYYENENVKGLHLNLGDTIMKDYEYLWNTVSKLVRDFEVGQPF 428
L H+SDL DE LLKNIAFYYE E+ + HLNLGD+I +DYE LWN VS LV++F VG+ F
Sbjct: 354 LNHVSDLYDEQLLKNIAFYYEFESTQEPHLNLGDSIRRDYEDLWNVVSHLVKEFNVGKSF 413
Query: 429 PLRTTKVCFLEKKPSPIKDSSNEMVPNLGFIPTSSFVVDKFAGDILKDLPFLKSDDPIVT 488
PLRTT+ FL ++ S I++ S E +P++GFIP +S V+D+F GD++KDLP LKSDDP+V
Sbjct: 414 PLRTTRRHFLRQEKSVIQEISLEKMPSVGFIPMTSAVIDEFVGDMMKDLPILKSDDPVVP 473
Query: 489 SLVKQKEFDELVHWHSHKPLSDDYDRSRCQFDEKSRDPRVLRSVQKYHVFQRFYGNSLET 548
SL KQK DEL+HWH+ + LSDDYDR +C DE+SRDP VL ++K +Q+FYG SLE+
Sbjct: 474 SLFKQKTSDELLHWHAQRLLSDDYDRIKCHVDEQSRDPHVLDFLKKIQDYQQFYGKSLES 533
Query: 549 VSSKIIVTQTIKSKKDFSGPKSKKAHETKAEIIARENKKRLFAREEQKEEQKWNALSFSI 608
+S+K+IVTQT + K+D SG + TK I +++KK+ F +E+Q + Q+ + L FSI
Sbjct: 534 ISTKVIVTQTTRPKEDSSGASGEILQNTKPHQITKKSKKKSFLKEDQNKAQQNDDLLFSI 593
Query: 609 EEQLKENLHSGIKSLEDFLKSCKSSCVKLQVEMVGLTACLKAWKEHCRSEEGKTTKDLSI 668
EE++K NLHSGI+ LED+L SC S+ VK VEM+GL AC KAWK+HCR E GK +KDLSI
Sbjct: 594 EEEMKNNLHSGIRKLEDYLTSCASNSVKFGVEMLGLIACFKAWKKHCRGE-GKISKDLSI 652
Query: 669 AVQVMKRIHSLMEKYSELLQEDDRQLIARCLKYLGFDELASSLHPAQDAENDVKVKKRNK 728
AVQ+MKRIHSL+E+Y E+L+ + Q IA+CLKYLGF++LA+SL P ++ K + K
Sbjct: 653 AVQMMKRIHSLLERYPEILEAEHHQYIAKCLKYLGFNDLANSLDPTLIGDD----KNKKK 708
Query: 729 YSVGIGPARFQLQYMGHYLIRDERKDPDPRVQDFIPDTWQRELLDVVDKNESAVIVAPTS 788
YS+ IGPARFQLQYMGHYLIRDERKD DPRVQDFIP+ WQ+ELLDVVDKNESAVIVAPTS
Sbjct: 709 YSIDIGPARFQLQYMGHYLIRDERKDRDPRVQDFIPNAWQQELLDVVDKNESAVIVAPTS 768
Query: 789 SGKTYASYYCMEKVLKESDDGVVVYVAPTKALVNQVAATVQNRFTKNLPSGEVLCGVFTR 848
SGKTYASYYCMEKVL+ESD GVVVYVAP K+LV QVAATV+NRFTK LP+G LCG FTR
Sbjct: 769 SGKTYASYYCMEKVLRESDVGVVVYVAPAKSLVGQVAATVENRFTKTLPAGRTLCGAFTR 828
Query: 849 EYRHDALNCQVLITVPACFEILLLAPHRQNWVKKIRYVIFDEVHCLGGEIGAEIWEHLLV 908
+Y H+ LNCQVLITVP CFEILLLAPHRQ WV++IRYVIFDEVH LG E+GA+ WE LLV
Sbjct: 829 DYCHNVLNCQVLITVPECFEILLLAPHRQKWVERIRYVIFDEVHYLGREVGAKFWELLLV 888
Query: 909 MIRCPFLALSATISNPEHLTEWLQSVKWYWKQEDKIIENNTASKRHVGRQAGFPKDYLQV 968
+IRCPFL LSATI+NP LT+WLQSVK YWKQ DKI+E S++ + F +D+
Sbjct: 889 IIRCPFLVLSATINNPNLLTKWLQSVKQYWKQADKIMEEKCISEKQADKCLNFLQDHSYK 948
Query: 969 KQSYKVRLVLYGERYNDLEKHVCSIKHGDIHFDHFHPCAALTTDHIERYGFPPDLTLSPR 1028
QSY+VRLVLYGERYNDLEKH+CS+KH D++FDHFHPCAALTTD IE+YGFPPDLTL+P+
Sbjct: 949 NQSYEVRLVLYGERYNDLEKHICSVKHDDVYFDHFHPCAALTTDIIEKYGFPPDLTLTPQ 1008
Query: 1029 ESIQLYDAMFQIWKSWPRAQELCPENFIHFNNKLVIKKMDARKYEESLKAELTSWIKNGN 1088
ESIQLYD M Q+W++WPRAQELCPE FI F NK+VIKK+DARKYEE+LKAELT+WIKNG
Sbjct: 1009 ESIQLYDTMAQVWETWPRAQELCPEEFILFKNKIVIKKLDARKYEENLKAELTNWIKNGQ 1068
Query: 1089 VEQARMVLQNLSPEADLSPENMITMFPLLVEKLRKMEKLPALFFLFKLGAVENAAESVST 1148
V++ + VL+NLSP++ S ++M+ MFPLLVEKLR+M+KLPA+FFLFK V A SV T
Sbjct: 1069 VKKVKRVLKNLSPDSLSSSKDMVKMFPLLVEKLRQMDKLPAIFFLFKNDDVGKRAGSVCT 1128
Query: 1149 FLKKKQETKRPPKADKEAHVMA--NKLRKVKKSIEKQKIIDEKSQKKTRNVDQSLIHEAE 1206
FL+K ETK P + ++V A L KV+K+ QK I +K+ KK +++ ++ AE
Sbjct: 1129 FLEKT-ETKSHPHTECHSYVFAIDEVLEKVRKT---QKRITKKNPKKAEKLERKKVYRAE 1184
Query: 1207 HDNLVKCLEKNLEIPQDCTYADQKAVDTE-------TLQKVFGRVKFERKGEELKALAER 1259
+ N ++ L K LEI +DCTYAD KA+ TE TL++V RV+F R G+ELKALA+R
Sbjct: 1185 YINFLENL-KILEISEDCTYADVKALHTEITRNKDSTLERVLPRVRFTRHGKELKALAQR 1243
Query: 1260 GIGYHHSAMSFKEKQLVEILFRKGYLRVVTATGTLALGVNMPCKSVVFAQNSVYLDALNY 1319
GIGYHHS+M FKEK+ VEILF KG +RVVTAT TLALG++MPCKSVVFAQ+SVYLDALNY
Sbjct: 1244 GIGYHHSSMYFKEKEFVEILFVKGLIRVVTATETLALGIHMPCKSVVFAQDSVYLDALNY 1303
Query: 1320 RQMSGRAGRRGQDLMGDVYFFDIPFPKIGKLIKSNVPELRGHFPLSITLVLRLMLLASKG 1379
RQMSGRAGRRGQDL+G+VYFFDIP PKI +L+ S+VPELRG FPLSITLVLRLMLLASKG
Sbjct: 1304 RQMSGRAGRRGQDLLGNVYFFDIPLPKIKRLLASSVPELRGQFPLSITLVLRLMLLASKG 1363
Query: 1380 DDPEDAKAKVLSVLKHSLLSFKQPRVMDMLKLYFLFSLQFLVKEGYLDQEGNPMGFAGLV 1439
DDPEDAKAKVLSVLKHSLLSFK+ R M+ LKLYFLFSLQ L+KE YL+++GNP FAGL
Sbjct: 1364 DDPEDAKAKVLSVLKHSLLSFKRRRAMETLKLYFLFSLQLLIKEDYLNKKGNPKKFAGLA 1423
Query: 1440 SHLHYHEPSNLVFVSFLVNGLFHDLCQPTRKGSKHFSQDVMEKLVLVLAHLFGRRYFPPK 1499
S+LH HEPSNLVFV+FL GLFH+LC+P KGS+ FSQDVMEKLVLVLA+LFGR+Y P K
Sbjct: 1424 SYLHGHEPSNLVFVNFLKRGLFHNLCKPAWKGSQQFSQDVMEKLVLVLANLFGRKYIPAK 1483
Query: 1500 FQDAHFEFYQSKVFLDDLPEDFSDALDEYNMKIMEDFTTFLRIVSKLADMNQEYQLPLSK 1559
FQ+A+ F QSKV L +LPEDF AL EYN+ +M+DF +FL I SK +M +E+QLPLS+
Sbjct: 1484 FQNANLSFSQSKVILAELPEDFKAALYEYNLAVMKDFASFLLIASKSVNMKKEHQLPLSR 1543
Query: 1560 IKFTGKECEDSQLVSHLMSCKEGRVAISPFVCLSGNFDDDLLRLETPNHVTLGTIGVNRS 1619
IKFTGKECEDSQLVSHLMSCK+GRVAISPFVCLSGN D+DLLR ET N V L T+GV+ +
Sbjct: 1544 IKFTGKECEDSQLVSHLMSCKKGRVAISPFVCLSGNTDNDLLRPETINQVILRTVGVSGT 1603
Query: 1620 QAPVLLSQKFDNRGRKMSLNAYALDFYKHGSLIGLVQDNRMNEGDAYYLLKDFALTIKSI 1679
QAP+L K DNRGR+M LNAY L+FYKH L L Q N M G LKDFA I++I
Sbjct: 1604 QAPLLWPWKLDNRGRRMPLNAYVLNFYKHNCLTRLDQKNGMRMGQLLKCLKDFAFNIQAI 1663
Query: 1680 SVSLRELCENEDDNVVLAFEQLSTTFWEKLNKV 1712
S SL ELCEN+ DNVVLAF+QLS TF+EKL ++
Sbjct: 1664 SDSLSELCENKRDNVVLAFKQLSQTFYEKLQEM 1696
>gi|193211480 superkiller viralicidic activity 2-like 2 [Homo sapiens]
Length = 1042
Score = 80.5 bits (197), Expect = 1e-14
Identities = 50/133 (37%), Positives = 75/133 (56%), Gaps = 10/133 (7%)
Query: 1251 EELKALAERGIGYHHSAMSFKEKQLVEILFRKGYLRVVTATGTLALGVNMPCKSVVF--- 1307
E + L +RGIG HH + K+ +EILF +G ++ + AT T A+G+NMP ++V+F
Sbjct: 442 EHVLPLLKRGIGIHHGGLLPILKETIEILFSEGLIKALFATETFAMGINMPARTVLFTNA 501
Query: 1308 ----AQNSVYLDALNYRQMSGRAGRRGQDLMGDVYFF--DIPFPKIGK-LIKSNVPELRG 1360
++ ++ + Y QMSGRAGRRG D G V + P IGK L+K + L
Sbjct: 502 RKFDGKDFRWISSGEYIQMSGRAGRRGMDDRGIVILMVDEKMSPTIGKQLLKGSADPLNS 561
Query: 1361 HFPLSITLVLRLM 1373
F L+ +VL L+
Sbjct: 562 AFHLTYNMVLNLL 574
Score = 77.4 bits (189), Expect = 1e-13
Identities = 54/174 (31%), Positives = 88/174 (50%), Gaps = 19/174 (10%)
Query: 762 FIPDTWQRELLDVVDKNESAVIVAPTSSGKTYASYYCMEKVLKESDDGVVVYVAPTKALV 821
FI D +QRE + VD N+S ++ A TS+GKT + Y + L+E V++ +P KAL
Sbjct: 138 FILDAFQREAIQCVDNNQSVLVSAHTSAGKTVCAEYAIALALREKQR--VIFTSPIKALS 195
Query: 822 NQVAATVQNRFTK-NLPSGEVLCGVFTREYRHDALNCQVLITVPACFEILLLAPHRQNWV 880
NQ + F L +G+V + +C V+ T EIL +R + V
Sbjct: 196 NQKYREMYEEFQDVGLMTGDVTI--------NPTASCLVMTT-----EILRSMLYRGSEV 242
Query: 881 -KKIRYVIFDEVHCLGGEIGAEIWEHLLVMI--RCPFLALSATISNPEHLTEWL 931
+++ +VIFDE+H + +WE ++++ ++ LSATI N EW+
Sbjct: 243 MREVAWVIFDEIHYMRDSERGVVWEETIILLPDNVHYVFLSATIPNARQFAEWI 296
>gi|67782311 superkiller viralicidic activity 2-like homolog [Homo
sapiens]
Length = 1246
Score = 79.7 bits (195), Expect = 2e-14
Identities = 56/166 (33%), Positives = 93/166 (56%), Gaps = 15/166 (9%)
Query: 1223 DCTYADQKAVDTETLQKVFGRVK-FERKGEELKALAE---RGIGYHHSAMSFKEKQLVEI 1278
D T + +K+ LQ+ R++ +R+ ++ ++E RG+G HHS + K++VE+
Sbjct: 590 DLTTSSEKSEIHLFLQRCLARLRGSDRQLPQVLHMSELLNRGLGVHHSGILPILKEIVEM 649
Query: 1279 LFRKGYLRVVTATGTLALGVNMPCKSVVF-----AQNSVYLDAL--NYRQMSGRAGRRGQ 1331
LF +G ++V+ AT T A+GVNMP ++VVF S + D L Y QM+GRAGRRG
Sbjct: 650 LFSRGLVKVLFATETFAMGVNMPARTVVFDSMRKHDGSTFRDLLPGEYVQMAGRAGRRGL 709
Query: 1332 DLMGDVYFF---DIP-FPKIGKLIKSNVPELRGHFPLSITLVLRLM 1373
D G V +P + +++ +L+ F L+ T++L L+
Sbjct: 710 DPTGTVILLCKGRVPEMADLHRMMMGKPSQLQSQFRLTYTMILNLL 755
Score = 70.9 bits (172), Expect = 1e-11
Identities = 53/186 (28%), Positives = 92/186 (49%), Gaps = 20/186 (10%)
Query: 755 PDPRVQ-DFIPDTWQRELLDVVDKNESAVIVAPTSSGKTYASYYCMEKVLKESDDGVVVY 813
P P Q F PD +Q++ + +++++S + A TS+GKT + Y + K +Y
Sbjct: 301 PQPAFQWAFEPDVFQKQAILHLERHDSVFVAAHTSAGKTVVAEYAIALAQKHMTR--TIY 358
Query: 814 VAPTKALVNQVAATVQNRFTKNLPSGEVLCGVFTREYR-HDALNCQVLITVPACFEILLL 872
+P KAL NQ +N F G+V G+ T + + H +C ++ T EIL
Sbjct: 359 TSPIKALSNQKFRDFRNTF------GDV--GLLTGDVQLHPEASCLIMTT-----EILRS 405
Query: 873 APHR-QNWVKKIRYVIFDEVHCLGGEIGAEIWEHLLVMI--RCPFLALSATISNPEHLTE 929
+ + ++ + +VIFDEVH + +WE +L+M+ + LSAT+ N +
Sbjct: 406 MLYSGSDVIRDLEWVIFDEVHYINDVERGVVWEEVLIMLPDHVSIILLSATVPNALEFAD 465
Query: 930 WLQSVK 935
W+ +K
Sbjct: 466 WIGRLK 471
>gi|139394648 DNA polymerase theta [Homo sapiens]
Length = 2590
Score = 75.9 bits (185), Expect = 3e-13
Identities = 34/81 (41%), Positives = 57/81 (70%), Gaps = 5/81 (6%)
Query: 1260 GIGYHHSAMSFKEKQLVEILFRKGYLRVVTATGTLALGVNMPCKSVVFAQNSVY----LD 1315
G+ +HH+ ++F+E+ ++E FR+G +RV+ AT TL+ GVN+P + V+ + ++ LD
Sbjct: 412 GVAFHHAGLTFEERDIIEGAFRQGLIRVLAATSTLSSGVNLPARRVII-RTPIFGGRPLD 470
Query: 1316 ALNYRQMSGRAGRRGQDLMGD 1336
L Y+QM GRAGR+G D +G+
Sbjct: 471 ILTYKQMVGRAGRKGVDTVGE 491
>gi|110556640 DNA helicase HEL308 [Homo sapiens]
Length = 1101
Score = 65.9 bits (159), Expect = 3e-10
Identities = 35/87 (40%), Positives = 50/87 (57%), Gaps = 3/87 (3%)
Query: 1253 LKALAERGIGYHHSAMSFKEKQLVEILFRKGYLRVVTATGTLALGVNMPCKSVVFAQNSV 1312
LK G+ YHHS ++ E++L+E + G L + T T TLA GVN+P + V+ V
Sbjct: 632 LKRTIPFGVAYHHSGLTSDERKLLEEAYSTGVLCLFTCTSTLAAGVNLPARRVILRAPYV 691
Query: 1313 ---YLDALNYRQMSGRAGRRGQDLMGD 1336
+L Y+QM GRAGR G D +G+
Sbjct: 692 AKEFLKRNQYKQMIGRAGRAGIDTIGE 718
>gi|40217847 activating signal cointegrator 1 complex subunit 3-like 1
[Homo sapiens]
Length = 2136
Score = 65.5 bits (158), Expect = 4e-10
Identities = 63/241 (26%), Positives = 106/241 (43%), Gaps = 25/241 (10%)
Query: 1116 LLVEKLRKMEKLPALFFLFKLGAVENAAESVSTFLKKKQ-------ETKRPPKADKEAHV 1168
L+ +R +E L L A E V+TFL+ + P ++ +V
Sbjct: 631 LVARAIRNIEMTQEDVRLIGLSATLPNYEDVATFLRVDPAKGLFYFDNSFRPVPLEQTYV 690
Query: 1169 MANKLRKVKKSIEKQKIIDEKSQKKT-RNVDQSLIHEAEHDNLVKCLEKNLEIPQDCT-- 1225
+ + +K+ +I+ EK + +N +H + +++ + +D
Sbjct: 691 GITEKKAIKRFQIMNEIVYEKIMEHAGKNQVLVFVHSRKETGKTARAIRDMCLEKDTLGL 750
Query: 1226 YADQKAVDTETLQKVFGRVKFER-KGEELKALAERGIGYHHSAMSFKEKQLVEILFRKGY 1284
+ + + TE L R + E+ K ELK L G HH+ M+ ++ LVE LF +
Sbjct: 751 FLREGSASTEVL-----RTEAEQCKNLELKDLLPYGFAIHHAGMTRVDRTLVEDLFADKH 805
Query: 1285 LRVVTATGTLALGVNMPCKSVVFAQNSVY---------LDALNYRQMSGRAGRRGQDLMG 1335
++V+ +T TLA GVN+P +V+ VY L AL+ QM GRAGR D G
Sbjct: 806 IQVLVSTATLAWGVNLPAHTVIIKGTQVYSPEKGRWTELGALDILQMLGRAGRPQYDTKG 865
Query: 1336 D 1336
+
Sbjct: 866 E 866
Score = 65.5 bits (158), Expect = 4e-10
Identities = 46/166 (27%), Positives = 80/166 (48%), Gaps = 8/166 (4%)
Query: 774 VVDKNESAVIVAPTSSGKTYASYYCMEKVLKESDDGVVVYVAPTKALVNQVAATVQNRFT 833
V + +++ + APT SGKT + + + ++L +S +G VY+ P +AL QV +F
Sbjct: 1339 VYNSDDNVFVGAPTGSGKTICAEFAILRMLLQSSEGRCVYITPMEALAEQVYMDWYEKFQ 1398
Query: 834 KNLPSGEVLCGVFTREYRHDALNCQVLITVPACFEILLLAPHRQNWVKKIRYVIFDEVHC 893
L VL T ++I+ P ++IL ++ V+ I + DEVH
Sbjct: 1399 DRLNKKVVLLTGETSTDLKLLGKGNIIISTPEKWDILSRRWKQRKNVQNINLFVVDEVHL 1458
Query: 894 LGGEIGAEI------WEHLLVMIRCP--FLALSATISNPEHLTEWL 931
+GGE G + ++ I P +ALS+++SN + + WL
Sbjct: 1459 IGGENGPVLEVICSRMRYISSQIERPIRIVALSSSLSNAKDVAHWL 1504
Score = 54.3 bits (129), Expect = 1e-06
Identities = 39/178 (21%), Positives = 84/178 (47%), Gaps = 24/178 (13%)
Query: 775 VDKNESAVIVAPTSSGKTYASYYCMEKVLKES---------DDGVVVYVAPTKALVNQVA 825
++ +E+ ++ APT +GKT + CM + + + DD ++Y+AP ++LV ++
Sbjct: 493 LETDENLLLCAPTGAGKTNVALMCMLREIGKHINMDGTINVDDFKIIYIAPMRSLVQEMV 552
Query: 826 ATVQNRFTKNLPSGEVLCGVFTREY---RHDALNCQVLITVPACFEILLLAPHRQNWVKK 882
+ F K L + + T ++ + + Q+++ P ++I+ + + +
Sbjct: 553 GS----FGKRLATYGITVAELTGDHQLCKEEISATQIIVCTPEKWDIITRKGGERTYTQL 608
Query: 883 IRYVIFDEVHCLGGEIGAEIWEHLLVMIR--------CPFLALSATISNPEHLTEWLQ 932
+R +I DE+H L + G + + IR + LSAT+ N E + +L+
Sbjct: 609 VRLIILDEIHLLHDDRGPVLEALVARAIRNIEMTQEDVRLIGLSATLPNYEDVATFLR 666
Score = 45.4 bits (106), Expect = 5e-04
Identities = 45/169 (26%), Positives = 72/169 (42%), Gaps = 36/169 (21%)
Query: 1177 KKSIEKQKIIDEKSQKKTR----NVDQSLIHEAEHDNLVKCLEKNLEIPQDCTYADQKAV 1232
K S +K I+ S+K+TR ++ + + + + C EK+L IP Y ++ +
Sbjct: 1552 KHSPKKPVIVFVPSRKQTRLTAIDILTTCAADIQRQRFLHCTEKDL-IP----YLEKLSD 1606
Query: 1233 DTETLQKVFGRVKFERKGEELKALAERGIGYHHSAMSFKEKQLVEILFRKGYLRVVTATG 1292
T LK G+GY H +S E++LVE LF G ++VV A+
Sbjct: 1607 ST------------------LKETLLNGVGYLHEGLSPMERRLVEQLFSSGAIQVVVASR 1648
Query: 1293 TLALGVNMPCKSVVFAQNSVYLDAL---------NYRQMSGRAGRRGQD 1332
+L G+N+ V+ Y + + QM G A R QD
Sbjct: 1649 SLCWGMNVAAHLVIIMDTQYYNGKIHAYVDYPIYDVLQMVGHANRPLQD 1697
>gi|169218225 PREDICTED: similar to U5 snRNP-specific 200kD protein,
partial [Homo sapiens]
Length = 1700
Score = 65.1 bits (157), Expect = 6e-10
Identities = 63/241 (26%), Positives = 106/241 (43%), Gaps = 25/241 (10%)
Query: 1116 LLVEKLRKMEKLPALFFLFKLGAVENAAESVSTFLKKKQ-------ETKRPPKADKEAHV 1168
L+ +R +E L L A E V+TFL+ + P ++ +V
Sbjct: 195 LVARAIRNIEMTQEDVRLIGLSATLPNYEDVATFLRVDPAKGLFYFDNSFRPVPLEQTYV 254
Query: 1169 MANKLRKVKKSIEKQKIIDEKSQKKT-RNVDQSLIHEAEHDNLVKCLEKNLEIPQDCT-- 1225
+ + +K+ +I+ EK + +N +H + +++ + +D
Sbjct: 255 GITEKKAIKRFQIMNEIVYEKIMEHAGKNQVLVFVHSRKETGKTARAIRDMCLEKDTLGL 314
Query: 1226 YADQKAVDTETLQKVFGRVKFER-KGEELKALAERGIGYHHSAMSFKEKQLVEILFRKGY 1284
+ + + TE L R + E+ K ELK L G HH+ M+ ++ LVE LF +
Sbjct: 315 FLREGSASTEVL-----RTEAEQCKNLELKDLLPYGFAIHHAGMTRVDRTLVEDLFGDKH 369
Query: 1285 LRVVTATGTLALGVNMPCKSVVFAQNSVY---------LDALNYRQMSGRAGRRGQDLMG 1335
++V+ +T TLA GVN+P +V+ VY L AL+ QM GRAGR D G
Sbjct: 370 IQVLVSTATLAWGVNLPAHTVIIKGTQVYSPEKGRWTELGALDILQMLGRAGRPQYDTKG 429
Query: 1336 D 1336
+
Sbjct: 430 E 430
Score = 59.7 bits (143), Expect = 2e-08
Identities = 43/166 (25%), Positives = 78/166 (46%), Gaps = 8/166 (4%)
Query: 774 VVDKNESAVIVAPTSSGKTYASYYCMEKVLKESDDGVVVYVAPTKALVNQVAATVQNRFT 833
V + +++ + APT SGKT + + + ++L ++ +G VY+ P + QV +F
Sbjct: 903 VYNSDDNVFVGAPTGSGKTICAEFAILRMLLQNSEGRCVYITPMRLWQEQVYMDWYEKFQ 962
Query: 834 KNLPSGEVLCGVFTREYRHDALNCQVLITVPACFEILLLAPHRQNWVKKIRYVIFDEVHC 893
L VL T ++I+ P ++IL ++ V+ I + DEVH
Sbjct: 963 DRLNKKVVLLTGETSTDLKLLGKGNIIISTPEKWDILSRRWKQRKNVQNINLFVVDEVHL 1022
Query: 894 LGGEIGAEI------WEHLLVMIRCP--FLALSATISNPEHLTEWL 931
+GGE G + ++ I P +ALS+++SN + + WL
Sbjct: 1023 IGGENGPVLEVICSRMRYISSQIERPIRIVALSSSLSNAKDVAHWL 1068
Score = 53.9 bits (128), Expect = 1e-06
Identities = 38/178 (21%), Positives = 84/178 (47%), Gaps = 24/178 (13%)
Query: 775 VDKNESAVIVAPTSSGKTYASYYCMEKVLKES---------DDGVVVYVAPTKALVNQVA 825
++ +E+ ++ APT +GKT + CM + + + DD ++Y+AP ++LV ++
Sbjct: 57 LETDENLLLCAPTGAGKTNVALMCMLREIGKHINMDGTINVDDFKIIYIAPMRSLVQEMV 116
Query: 826 ATVQNRFTKNLPSGEVLCGVFTREY---RHDALNCQVLITVPACFEILLLAPHRQNWVKK 882
+ F K L + + T ++ + + Q+++ P ++I+ + + +
Sbjct: 117 GS----FGKRLATYGITVAELTGDHQLCKEEISATQIIVCTPEKWDIITRKGGERTYTQL 172
Query: 883 IRYVIFDEVHCLGGEIGAEIWEHLLVMIR--------CPFLALSATISNPEHLTEWLQ 932
+R ++ DE+H L + G + + IR + LSAT+ N E + +L+
Sbjct: 173 VRLIVLDEIHLLHDDRGPVLEALVARAIRNIEMTQEDVRLIGLSATLPNYEDVATFLR 230
Score = 44.7 bits (104), Expect = 8e-04
Identities = 45/169 (26%), Positives = 72/169 (42%), Gaps = 36/169 (21%)
Query: 1177 KKSIEKQKIIDEKSQKKTR----NVDQSLIHEAEHDNLVKCLEKNLEIPQDCTYADQKAV 1232
K S +K I+ S+K+TR ++ + + + + C EK+L IP Y ++ +
Sbjct: 1116 KHSPKKPVIVFVPSRKQTRLTAIDILTTCAADIQRQRFLHCTEKDL-IP----YLEKLSD 1170
Query: 1233 DTETLQKVFGRVKFERKGEELKALAERGIGYHHSAMSFKEKQLVEILFRKGYLRVVTATG 1292
T LK G+GY H +S E++LVE LF G ++VV A+
Sbjct: 1171 ST------------------LKETLLNGVGYLHEGLSPMERRLVEQLFSSGAIQVVVASR 1212
Query: 1293 TLALGVNMPCKSVVFAQNSVYLDAL---------NYRQMSGRAGRRGQD 1332
+L G+N+ V+ Y + + QM G A R QD
Sbjct: 1213 SLCWGMNVAAHLVIIMDTLYYNGKIHAYVDYPIYDVLQMVGHANRPLQD 1261
>gi|76880486 activating signal cointegrator 1 complex subunit 3
isoform a [Homo sapiens]
Length = 2202
Score = 60.1 bits (144), Expect = 2e-08
Identities = 32/97 (32%), Positives = 52/97 (53%), Gaps = 9/97 (9%)
Query: 1249 KGEELKALAERGIGYHHSAMSFKEKQLVEILFRKGYLRVVTATGTLALGVNMPCKSVVFA 1308
+ ++++ L G HH+ M +++ LVE LF G+++V+ T TLA GVN+P +V+
Sbjct: 767 RNKQVRELFPDGFSIHHAGMLRQDRNLVENLFSNGHIKVLVCTATLAWGVNLPAHAVIIK 826
Query: 1309 QNSVY---------LDALNYRQMSGRAGRRGQDLMGD 1336
+Y L L+ Q+ GRAGR D G+
Sbjct: 827 GTQIYAAKRGSFVDLGILDVMQIFGRAGRPQFDKFGE 863
Score = 57.0 bits (136), Expect = 2e-07
Identities = 43/164 (26%), Positives = 80/164 (48%), Gaps = 16/164 (9%)
Query: 780 SAVIVAPTSSGKTYASYYCMEKVLKESDDGVVVYVAPTKALVNQVAATVQNRFTKNLPSG 839
+ ++ APT SGKT A+ + +V + VY+AP KALV + + R + L
Sbjct: 1344 NVLLGAPTGSGKTVAAELAIFRVFNKYPTSKAVYIAPLKALVRERMDDWKVRIEEKLGKK 1403
Query: 840 EV-LCGVFTREYRHDALNCQVLITVPACFEILLLAPHRQNWVKKIRYVIFDEVHCLGGEI 898
+ L G T + + A +++T P ++ + + +N+V+++ +I DE+H LG E
Sbjct: 1404 VIELTGDVTPDMKSIA-KADLIVTTPEKWDGVSRSWQNRNYVQQVTILIIDEIHLLGEER 1462
Query: 899 GAEIWEHLLVMIRCPFLA-----------LSATISNPEHLTEWL 931
G + +++ R F++ LS ++N L +WL
Sbjct: 1463 GPVL---EVIVSRTNFISSHTEKPVRIVGLSTALANARDLADWL 1503
Score = 49.3 bits (116), Expect = 3e-05
Identities = 34/97 (35%), Positives = 47/97 (48%), Gaps = 11/97 (11%)
Query: 1249 KGEELKALAERGIGYHHSAMSFKEKQLVEILFRKGYLRVVTATGTLALGVNMPCKSVVFA 1308
+ LK GIG HH+ + ++++ VE LF ++V+ AT TLA GVN P V+
Sbjct: 1604 RDSNLKLTLAFGIGMHHAGLHERDRKTVEELFVNCKVQVLIATSTLAWGVNFPAHLVII- 1662
Query: 1309 QNSVYLDALNYR----------QMSGRAGRRGQDLMG 1335
+ + Y D R QM GRAGR D G
Sbjct: 1663 KGTEYYDGKTRRYVDFPITDVLQMMGRAGRPQFDDQG 1699
Score = 45.4 bits (106), Expect = 5e-04
Identities = 49/168 (29%), Positives = 78/168 (46%), Gaps = 28/168 (16%)
Query: 778 NESAVIVAPTSSGKT-YASYYCMEKVLKESDDGV-------VVYVAPTKALVNQVAATVQ 829
NE+ +I APT +GKT A + ++ + GV +VYVAP KAL AA +
Sbjct: 492 NENMLICAPTGAGKTNIAMLTVLHEIRQHFQQGVIKKNEFKIVYVAPMKAL----AAEMT 547
Query: 830 NRFTKNLPSGEVLCGVFTREY---RHDALNCQVLITVPACFEILLLAPHRQNWVKKI-RY 885
+ F++ L ++ T + + + L Q+L+T P ++++ + +I R
Sbjct: 548 DYFSRRLEPLGIIVKELTGDMQLSKSEILRTQMLVTTPEKWDVVTRKSVGDVALSQIVRL 607
Query: 886 VIFDEVHCLGGEIGAEI----------WEHLLVMIRCPFLALSATISN 923
+I DEVH L + G + E MIR L LSAT+ N
Sbjct: 608 LILDEVHLLHEDRGPVLESIVARTLRQVESTQSMIR--ILGLSATLPN 653
>gi|130484567 HFM1 protein [Homo sapiens]
Length = 1435
Score = 56.6 bits (135), Expect = 2e-07
Identities = 38/135 (28%), Positives = 62/135 (45%), Gaps = 8/135 (5%)
Query: 1202 IHEAEHDNLVKCL-EKNLEIPQDCTYADQKAVDTETLQKVFGRVKFERKGEELKALAERG 1260
++ + LV C K ++ D K + T ++ + + + +L+ + + G
Sbjct: 523 MYSDQKPTLVFCATRKGVQQAASVLVKDAKFIMTVEQKQRLQKYAYSVRDSKLRDILKDG 582
Query: 1261 IGYHHSAMSFKEKQLVEILFRKGYLRVVTATGTLALGVNMPCKSVVFAQNSVYLDAL--- 1317
YHH+ M ++++VE F G L V+ T TLA+GVN+P VV Y L
Sbjct: 583 AAYHHAGMELSDRKVVEGAFTVGDLPVLFTTSTLAMGVNLPAHLVVIKSTMHYAGGLFEE 642
Query: 1318 ----NYRQMSGRAGR 1328
+ QM GRAGR
Sbjct: 643 YSETDILQMIGRAGR 657
Score = 52.0 bits (123), Expect = 5e-06
Identities = 48/186 (25%), Positives = 81/186 (43%), Gaps = 33/186 (17%)
Query: 773 DVVDKNESAVIVAPTSSGKTYASYYCMEKVLKESD----DGVVVYVAPTKALVNQVAATV 828
D++ + + VI APT SGKT + ++L E + +VY+AP KAL +Q
Sbjct: 291 DLLYTDRNFVICAPTGSGKTVVFELAITRLLMEVPLPWLNIKIVYMAPIKALCSQRFDDW 350
Query: 829 QNRF------TKNLPSGEVLCGVFTREYRHDALNCQVLITVPACFEILLLAPHRQNWVKK 882
+ +F K L V+ +F ++ H +++T P ++ + + V+
Sbjct: 351 KEKFGPIGLNCKELTGDTVMDDLFEIQHAH------IIMTTPEKWDSMTRKWRDNSLVQL 404
Query: 883 IRYVIFDEVHCLGGEIGAEIWEHLL-----------------VMIRCPFLALSATISNPE 925
+R + DEVH + E E ++ I F+A+SATI N E
Sbjct: 405 VRLFLIDEVHIVKDENRGPTLEVVVSRMKTVQSVSQTLKNTSTAIPMRFVAVSATIPNAE 464
Query: 926 HLTEWL 931
+ EWL
Sbjct: 465 DIAEWL 470
>gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 42.4 bits (98), Expect = 0.004
Identities = 34/136 (25%), Positives = 66/136 (48%), Gaps = 7/136 (5%)
Query: 569 KSKKA-----HETKAEIIARENKKRLFAREEQKEEQKWNALSFSIEEQ--LKENLHSGIK 621
K KKA +T ++ A E+K + + K EQ+ + L S+E++ L+ +L +
Sbjct: 1000 KEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKR 1059
Query: 622 SLEDFLKSCKSSCVKLQVEMVGLTACLKAWKEHCRSEEGKTTKDLSIAVQVMKRIHSLME 681
LE LK + S + ++ E L LK + + + K + ++ +Q+ K+I L
Sbjct: 1060 KLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQA 1119
Query: 682 KYSELLQEDDRQLIAR 697
+ EL +E + + +R
Sbjct: 1120 RIEELEEEIEAERASR 1135
>gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 42.4 bits (98), Expect = 0.004
Identities = 34/136 (25%), Positives = 66/136 (48%), Gaps = 7/136 (5%)
Query: 569 KSKKA-----HETKAEIIARENKKRLFAREEQKEEQKWNALSFSIEEQ--LKENLHSGIK 621
K KKA +T ++ A E+K + + K EQ+ + L S+E++ L+ +L +
Sbjct: 1000 KEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKR 1059
Query: 622 SLEDFLKSCKSSCVKLQVEMVGLTACLKAWKEHCRSEEGKTTKDLSIAVQVMKRIHSLME 681
LE LK + S + ++ E L LK + + + K + ++ +Q+ K+I L
Sbjct: 1060 KLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQA 1119
Query: 682 KYSELLQEDDRQLIAR 697
+ EL +E + + +R
Sbjct: 1120 RIEELEEEIEAERASR 1135
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 42.0 bits (97), Expect = 0.005
Identities = 59/284 (20%), Positives = 119/284 (41%), Gaps = 36/284 (12%)
Query: 440 KKPSPIKDSSNEMVPNLGFIPTSSFVVDKFAGDILKDLPFLKSD-DPIVTSLVKQKEFDE 498
KK ++ +E+ +L S +K D+ ++L LK++ + + S Q+E
Sbjct: 1104 KKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQEL-- 1161
Query: 499 LVHWHSHKPLSDDYDRSRCQFDEKSRDPRVLRSVQKYHVFQRFYGNSLETVSSKIIVTQT 558
S + + + + + K+ + ++ QK+ ++E ++ ++ T+
Sbjct: 1162 ----RSKREQEVNILKKTLEEEAKTHEAQIQEMRQKH-------SQAVEELAEQLEQTKR 1210
Query: 559 IKSKKDFSGPKSKKAHETKAEIIARENKKRLFAREEQKEEQKWNALSFSIEEQLKENLHS 618
+K+ + K+K+ E + +A E K L + + + ++K +E QL+E L
Sbjct: 1211 VKANLE----KAKQTLENERGELANEVKVLLQGKGDSEHKRK------KVEAQLQE-LQV 1259
Query: 619 GIKSLEDFLKSCKSSCVKLQVEMVGLTACLKAWKEHCRSEEGKTTKDLSIAVQVMKRIHS 678
E KLQVE+ +T L S+ K TKD S + S
Sbjct: 1260 KFNEGERVRTELADKVTKLQVELDNVTGLLS----QSDSKSSKLTKDFSA-------LES 1308
Query: 679 LMEKYSELLQEDDRQLIARCLKYLGFDELASSLHPAQDAENDVK 722
++ ELLQE++RQ ++ K ++ +S + E + K
Sbjct: 1309 QLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAK 1352
>gi|30581135 structural maintenance of chromosomes 1A [Homo sapiens]
Length = 1233
Score = 42.0 bits (97), Expect = 0.005
Identities = 59/264 (22%), Positives = 113/264 (42%), Gaps = 41/264 (15%)
Query: 490 LVKQKEFDELVHWHSHKPLSDDYDRSRCQFDEKSRDPR----VLRSVQKYHVFQRFYGNS 545
+VK +E D ++H K ++ + ++ + +E R R V+R+ + +F + Y N
Sbjct: 175 MVKAEE-DTQFNYHRKKNIAAERKEAKQEKEEADRYQRLKDEVVRAQVQLQLF-KLYHNE 232
Query: 546 LETVS-SKIIVTQTIKSKKDFSGPKSKKAHETKAEIIARENKKRL--FAREEQKEEQKWN 602
+E +K + ++ + +KD K K E +E KK L RE+Q+ E++
Sbjct: 233 VEIEKLNKELASKNKEIEKD-------KKRMDKVEDELKEKKKELGKMMREQQQIEKEIK 285
Query: 603 ALSFSIEEQ------LKENLHSGIKSLEDFLKSC----------KSSCVKLQVEMVGLTA 646
+ ++ KEN IK LE KS K +L+ EM+ +
Sbjct: 286 EKDSELNQKRPQYIKAKENTSHKIKKLEAAKKSLQNAQKHYKKRKGDMDELEKEMLSVEK 345
Query: 647 CLKAWKEHCRSEEGKTTKDLSIAVQVMKRIHSLMEKYSELLQEDDRQLIARCLKYLGFDE 706
+ ++E E +DL++ +K+ H L E+ S+ +A+ L+ D+
Sbjct: 346 ARQEFEERMEEESQSQGRDLTLEENQVKKYHRLKEEASK-----RAATLAQELEKFNRDQ 400
Query: 707 LAS----SLHPAQDAENDVKVKKR 726
A L + E + K+K++
Sbjct: 401 KADQDRLDLEERKKVETEAKIKQK 424
>gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo
sapiens]
Length = 1939
Score = 42.0 bits (97), Expect = 0.005
Identities = 34/136 (25%), Positives = 65/136 (47%), Gaps = 7/136 (5%)
Query: 569 KSKKA-----HETKAEIIARENKKRLFAREEQKEEQKWNALSFSIEEQLK--ENLHSGIK 621
K KKA +T ++ E+K + + K EQ+ + L S+E++ K +L +
Sbjct: 998 KEKKALQEAHQQTLDDLQMEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLCMDLERAKR 1057
Query: 622 SLEDFLKSCKSSCVKLQVEMVGLTACLKAWKEHCRSEEGKTTKDLSIAVQVMKRIHSLME 681
LE LK + S + + + L LK + + +GK + ++A+Q+ K+I L
Sbjct: 1058 KLEGDLKLAQESTMDTENDKQQLNEKLKKKEFEMSNLQGKIEDEQALAIQLQKKIKELQA 1117
Query: 682 KYSELLQEDDRQLIAR 697
+ EL +E + + +R
Sbjct: 1118 RIEELEEEIEAERASR 1133
>gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo
sapiens]
Length = 1939
Score = 39.3 bits (90), Expect = 0.033
Identities = 32/136 (23%), Positives = 65/136 (47%), Gaps = 7/136 (5%)
Query: 569 KSKKA-----HETKAEIIARENKKRLFAREEQKEEQKWNALSFSIEEQ--LKENLHSGIK 621
K KKA +T ++ A E+K + + K EQ+ + L S+E++ ++ +L +
Sbjct: 998 KEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKR 1057
Query: 622 SLEDFLKSCKSSCVKLQVEMVGLTACLKAWKEHCRSEEGKTTKDLSIAVQVMKRIHSLME 681
LE LK + S + ++ + L LK + + K + ++ +Q+ K+I L
Sbjct: 1058 KLEGDLKLAQESTMDIENDKQQLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQA 1117
Query: 682 KYSELLQEDDRQLIAR 697
+ EL +E + + +R
Sbjct: 1118 RIEELEEEIEAERASR 1133
Score = 31.2 bits (69), Expect = 9.0
Identities = 23/108 (21%), Positives = 44/108 (40%), Gaps = 3/108 (2%)
Query: 584 ENKKRLFAREEQKEE--QKWNALSFSIEEQLKENLHSGIKSLEDFLKSCKSSCVKLQVEM 641
E KK+L R + EE + NA S+E+ K+ L + ++ L ++ ++C L +
Sbjct: 1392 EAKKKLAQRLQDAEEHVEAVNAKCASLEKT-KQRLQNEVEDLMIDVERTNAACAALDKKQ 1450
Query: 642 VGLTACLKAWKEHCRSEEGKTTKDLSIAVQVMKRIHSLMEKYSELLQE 689
L WK+ C + + + + + Y E L +
Sbjct: 1451 RNFDKILAEWKQKCEETHAELEASQKESRSLSTELFKIKNAYEESLDQ 1498
>gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo
sapiens]
Length = 1937
Score = 39.3 bits (90), Expect = 0.033
Identities = 32/136 (23%), Positives = 66/136 (48%), Gaps = 7/136 (5%)
Query: 569 KSKKA-----HETKAEIIARENKKRLFAREEQKEEQKWNALSFSIEEQ--LKENLHSGIK 621
K KKA +T ++ A E+K + + + K EQ+ + L S+E++ L+ +L +
Sbjct: 997 KEKKALQETHQQTLDDLQAEEDKVNILTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKR 1056
Query: 622 SLEDFLKSCKSSCVKLQVEMVGLTACLKAWKEHCRSEEGKTTKDLSIAVQVMKRIHSLME 681
LE LK + S + ++ + L L+ + + K + ++ +Q+ K+I L
Sbjct: 1057 KLEGDLKLAQESTMDMENDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQA 1116
Query: 682 KYSELLQEDDRQLIAR 697
+ EL +E + + +R
Sbjct: 1117 RIEELGEEIEAERASR 1132
>gi|116812616 RecQ protein-like 4 [Homo sapiens]
Length = 1208
Score = 38.5 bits (88), Expect = 0.057
Identities = 24/68 (35%), Positives = 36/68 (52%), Gaps = 1/68 (1%)
Query: 1264 HHSAMSFKEKQLVEILFRKGYLRVVTATGTLALGVNMPCKSVVFAQNSVYLDALNYRQMS 1323
+H+ M +E++ V+ F +G LRVV AT +G++ P V + +Y Q
Sbjct: 744 YHAGMCSRERRRVQRAFMQGQLRVVVATVAFGMGLDRPDVRAVL-HLGLPPSFESYVQAV 802
Query: 1324 GRAGRRGQ 1331
GRAGR GQ
Sbjct: 803 GRAGRDGQ 810
>gi|195976782 Paf1/RNA polymerase II complex component [Homo
sapiens]
Length = 710
Score = 36.6 bits (83), Expect = 0.22
Identities = 30/138 (21%), Positives = 61/138 (44%), Gaps = 6/138 (4%)
Query: 495 EFDELVHWHSHKPLSDDYDRSRC-QFDEKSRDPRVLRSVQKYHVFQRFYG--NSLETVSS 551
E +E + + D+ DR+R Q EK R+ + ++K V +R + L+T
Sbjct: 174 EDEEFHDGYGEDLMGDEEDRARLEQMTEKEREQELFNRIEKREVLKRRFEIKKKLKTAKK 233
Query: 552 KIIVTQTIKSKKDFSGPKSKKAHETKAEIIARENKKRLFAREEQKEEQKWNALSFSIEEQ 611
K + K KK + KK + + + NK+R R+E+ +++ E +
Sbjct: 234 K---EKKEKKKKQEEEQEKKKLTQIQESQVTSHNKERRSKRDEKLDKKSQAMEELKAERE 290
Query: 612 LKENLHSGIKSLEDFLKS 629
++N + + + + LK+
Sbjct: 291 KRKNRTAELLAKKQPLKT 308
>gi|14591902 RecQ protein-like [Homo sapiens]
Length = 649
Score = 36.2 bits (82), Expect = 0.28
Identities = 27/99 (27%), Positives = 46/99 (46%), Gaps = 7/99 (7%)
Query: 1246 FERKGEELKALAERGIGYH----HSAMSFKEKQLVEILFRKGYLRVVTATGTLALGVNMP 1301
F +K E ++ + +G H H+ + ++K V + ++VV AT +G++ P
Sbjct: 322 FSQKDSEQVTVSLQNLGIHAGAYHANLEPEDKTTVHRKWSANEIQVVVATVAFGMGIDKP 381
Query: 1302 CKSVVFAQNSVYLDALNYRQMSGRAGRRGQDLMGDVYFF 1340
V +S+ NY Q SGRAGR D+ D +
Sbjct: 382 DVRFVI-HHSMSKSMENYYQESGRAGR--DDMKADCILY 417
>gi|14591904 RecQ protein-like [Homo sapiens]
Length = 649
Score = 36.2 bits (82), Expect = 0.28
Identities = 27/99 (27%), Positives = 46/99 (46%), Gaps = 7/99 (7%)
Query: 1246 FERKGEELKALAERGIGYH----HSAMSFKEKQLVEILFRKGYLRVVTATGTLALGVNMP 1301
F +K E ++ + +G H H+ + ++K V + ++VV AT +G++ P
Sbjct: 322 FSQKDSEQVTVSLQNLGIHAGAYHANLEPEDKTTVHRKWSANEIQVVVATVAFGMGIDKP 381
Query: 1302 CKSVVFAQNSVYLDALNYRQMSGRAGRRGQDLMGDVYFF 1340
V +S+ NY Q SGRAGR D+ D +
Sbjct: 382 DVRFVI-HHSMSKSMENYYQESGRAGR--DDMKADCILY 417
>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
sapiens]
Length = 1935
Score = 35.8 bits (81), Expect = 0.37
Identities = 32/146 (21%), Positives = 65/146 (44%), Gaps = 6/146 (4%)
Query: 554 IVTQTIKSKKDFSGPKSKKAHETKAEIIARENKKRLFAREEQKEEQKWNALSFSIEEQ-- 611
I+ + K KK + + +AE E+K + + K EQ+ + L S+E++
Sbjct: 988 IIAKLTKEKKALQEAHQQALDDLQAE----EDKVNTLTKAKVKLEQQVDDLEGSLEQEKK 1043
Query: 612 LKENLHSGIKSLEDFLKSCKSSCVKLQVEMVGLTACLKAWKEHCRSEEGKTTKDLSIAVQ 671
++ +L + LE LK + S + L+ + L LK + + + ++ Q
Sbjct: 1044 VRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQ 1103
Query: 672 VMKRIHSLMEKYSELLQEDDRQLIAR 697
+ K++ L + EL +E + + AR
Sbjct: 1104 LQKKLKELQARIEELEEELEAERTAR 1129
>gi|21735569 claspin [Homo sapiens]
Length = 1339
Score = 35.8 bits (81), Expect = 0.37
Identities = 47/219 (21%), Positives = 97/219 (44%), Gaps = 36/219 (16%)
Query: 552 KIIVTQTIKSKKDFSGPKSK------KAHETKAEIIARENKKRLFAREEQKEEQKWNALS 605
+I V++ +K++K S+ +T + ENK+ L+A + K ++ + ++
Sbjct: 49 EIFVSKKLKNRKVLQDSDSETEDTNASPEKTTYDSAEEENKENLYAGKNTKIKRIYKTVA 108
Query: 606 FSIEEQLKENLHSGIKSLEDFLKSCKSSCVKLQVEMVGLTACLKAWKEHCRSEEG----- 660
S E ++++L+ ++LE +K C ++ T K+ K+H +EG
Sbjct: 109 DSDESYMEKSLYQ--ENLEAQVKPCLELSLQ-SGNSTDFTTDRKSSKKHIHDKEGTAGKA 165
Query: 661 --KTTKDLSIAVQVMKRIHSLMEKYSELLQEDDRQ--------LIARCLKYLGFDELASS 710
K+ + L + M++I L +K ++ ++D Q L+ + L G ++ +S
Sbjct: 166 KVKSKRRLEKEERKMEKIRQLKKKETKNQEDDVEQPFNDSGCLLVDKDLFETGLEDENNS 225
Query: 711 LHPAQDAE----------NDVKVKKRNKYSVGIGPARFQ 739
P +D E N VK K+ + S+ G F+
Sbjct: 226 --PLEDEESLESIRAAVKNKVKKHKKKEPSLESGVHSFE 262
>gi|67782362 DEAH (Asp-Glu-Ala-His) box polypeptide 29 [Homo
sapiens]
Length = 1369
Score = 35.8 bits (81), Expect = 0.37
Identities = 44/231 (19%), Positives = 93/231 (40%), Gaps = 12/231 (5%)
Query: 560 KSKKDFSGPKSKKAHETKAEIIARENKKRLFAREEQKEEQKWNALSFSIEEQLKEN---L 616
K+K PKSK E K + + +A ++ +EE+ N+ S EE+ N L
Sbjct: 206 KTKTYEEDPKSKPKKEEKNMEVNMKEWILRYAEQQNEEEKNENSKSLEEEEKFDPNERYL 265
Query: 617 HSGIKSLEDFLKSCKSSCVKLQVEMVGLTACLKAWKEHCRSEEGKTTKDLSIAVQVMKRI 676
H K L+ +++ KL+ G + ++ R E T +D + MK
Sbjct: 266 HLAAKLLD---AKEQAATFKLEKNKQGQKEAQEKIRKFQREME--TLEDHPVFNPAMKIS 320
Query: 677 HSLMEKYSELLQEDDRQLIARCLKYLGFDELASSLHPAQDAENDVKVKKRNKYSVGIGPA 736
H E+ + + L + F++ A++ +D + + + Y+
Sbjct: 321 HQQNERKKPPVATEGES----ALNFNLFEKSAAATEEEKDKKKEPHDVRNFDYTARSWTG 376
Query: 737 RFQLQYMGHYLIRDERKDPDPRVQDFIPDTWQRELLDVVDKNESAVIVAPT 787
+ Q++ ++ ++ K P+P + + + + V+ + ++V PT
Sbjct: 377 KSPKQFLIDWVRKNLPKSPNPSFEKVPVGRYWKCRVRVIKSEDDVLVVCPT 427
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 35.8 bits (81), Expect = 0.37
Identities = 47/196 (23%), Positives = 86/196 (43%), Gaps = 13/196 (6%)
Query: 508 LSDDYDRSRCQFDEKSRDPRVLRSVQKYHVFQRFYGNSLETVSSKIIVTQT---IKSKKD 564
LS D+S + E + ++ + +K+ Q + SLE I V QT + ++
Sbjct: 178 LSQSQDKSLRRIAELREELQMDQQAKKH--LQEEFDASLEEKDQYISVLQTQVSLLKQRL 235
Query: 565 FSGPKSKKAHETKAEIIARENKKRLFAREEQKEEQKWNALSFSIEEQLKENLHSGIKSLE 624
+GP + + ++ E + +F +EE E + + E L +K E
Sbjct: 236 RNGPMNVDVLKPLPQL---EPQAEVFTKEENPESDGEPVVEDGTSVKTLETLQQRVKRQE 292
Query: 625 DFLKSCKSSCVKLQVEMVGLTACLKAWKEHC--RSEEGKTTKDLSIAVQVMKRIHSLMEK 682
+ LK CK + + + LT+ +A +E R +E + KDL +A + K I L +
Sbjct: 293 NLLKRCKETIQSHKEQCTLLTSEKEALQEQLDERLQELEKIKDLHMA-EKTKLITQLRDA 351
Query: 683 YS--ELLQEDDRQLIA 696
+ E L++D +IA
Sbjct: 352 KNLIEQLEQDKGMVIA 367
Score = 33.1 bits (74), Expect = 2.4
Identities = 41/202 (20%), Positives = 93/202 (46%), Gaps = 23/202 (11%)
Query: 1069 ARKYEESLKAELTSWIKNGN-VEQARMVLQNLSPEADLSPENMITMFPLLVEKLRKMEKL 1127
+ K+ E K + + ++ N V++ ++ L+ S EA E + LL E+L + K
Sbjct: 1439 SNKFSEWKKKAQSRFTQHQNTVKELQIQLELKSKEAYEKDEQI----NLLKEELDQQNK- 1493
Query: 1128 PALFFLFKLGAVENAAESVSTFLKKKQETKRPPKADKEAHVMANKLRKVKKSIEKQKIID 1187
+ ++ E + ++KK+ + A +M + +K+IE + + +
Sbjct: 1494 -------RFDCLKGEMEDDKSKMEKKESNLETELKSQTARIMELEDHITQKTIEIESLNE 1546
Query: 1188 E-KSQKKTRNVD-QSLIHEAEH--------DNLVKCLEKNLEIPQDCTYADQKAVDTETL 1237
K+ + ++++ + L+ + +H DN VK E+ + ++ Y+ + ++T+
Sbjct: 1547 VLKNYNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKK 1606
Query: 1238 QKVFGRVKFERKGEELKALAER 1259
+ + + K EELKAL +R
Sbjct: 1607 ELEHVNLSVKSKEEELKALEDR 1628
Score = 32.3 bits (72), Expect = 4.1
Identities = 51/216 (23%), Positives = 92/216 (42%), Gaps = 21/216 (9%)
Query: 533 QKYHVFQRFYGNSLETVSSKIIVTQTIKSKKDFSGPKSKKAHETKAEI------IARENK 586
+K + QR ETVSS + + + K HE ++ I + +NK
Sbjct: 1747 EKEKLLQRVGQEKEETVSSHFEMRCQYQERLIKLEHAEAKQHEDQSMIGHLQEELEEKNK 1806
Query: 587 KR--LFAREEQKEEQKWNALSFSIEEQLKENLHSGIKSLEDFLKSCKSSCVKLQVEMVGL 644
K + A+ +KE K N Q K+NL + ++ L+ + +C L+ ++ L
Sbjct: 1807 KYSLIVAQHVEKEGGKNNI-------QAKQNLENVFDDVQKTLQEKELTCQILEQKIKEL 1859
Query: 645 TACLKAWKEHCRSEEGKTTKDLSIAVQVMKRIHSLMEKYSELLQEDDRQLIARCLKYLGF 704
+CL KE R E + T +Q ++++ K +ELL+E+ + + +L
Sbjct: 1860 DSCLVRQKEVHRVEMEELTSKYE-KLQALQQMDG-RNKPTELLEENTEE---KSKSHLVQ 1914
Query: 705 DELASSLHPA-QDAENDVKVKKRNKYSVGIGPARFQ 739
+L S++ D E + +R K +G R Q
Sbjct: 1915 PKLLSNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQ 1950
>gi|13129006 nucleolar protein GU2 [Homo sapiens]
Length = 737
Score = 35.8 bits (81), Expect = 0.37
Identities = 21/67 (31%), Positives = 37/67 (55%), Gaps = 1/67 (1%)
Query: 1265 HSAMSFKEKQLVEILFRKGYLRVVTATGTLALGVNMPCKSVVFAQNSVYLDALNYRQMSG 1324
H ++ ++++ FR+G +V+ AT A G+++P +V Q+S D +Y SG
Sbjct: 419 HGDIAQSQREITLKGFREGSFKVLVATNVAARGLDIPEVDLVI-QSSPPQDVESYIHRSG 477
Query: 1325 RAGRRGQ 1331
R GR G+
Sbjct: 478 RTGRAGR 484
Score = 32.3 bits (72), Expect = 4.1
Identities = 30/125 (24%), Positives = 57/125 (45%), Gaps = 11/125 (8%)
Query: 775 VDKNESAVIVAPTSSGKTYASYYCM-------EKVLKESDDGVVVYVAPTKALVNQVAAT 827
V + + + A T +GKT++ + ++ +K+S V+ +APT+ L NQVA
Sbjct: 171 VYEGKDLIAQARTGTGKTFSFAIPLIERLQRNQETIKKSRSPKVLVLAPTRELANQVAKD 230
Query: 828 VQNRFTKNLPSGEVLCGV-FTREYRHDALNCQVLITVPACFEILLLAPHRQNWVKKIRYV 886
++ T+ L G + + H +L+ P + L + + K+R+V
Sbjct: 231 FKD-ITRKLSVACFYGGTSYQSQINHIRNGIDILVGTPGRIKDHLQSGRLD--LSKLRHV 287
Query: 887 IFDEV 891
+ DEV
Sbjct: 288 VLDEV 292
>gi|40807445 protein regulator of cytokinesis 1 isoform 3 [Homo
sapiens]
Length = 566
Score = 35.4 bits (80), Expect = 0.48
Identities = 39/123 (31%), Positives = 55/123 (44%), Gaps = 25/123 (20%)
Query: 579 EIIARENKKRLFAREEQKEEQKWNALSFSI--EEQLKENLHSGIKSLEDFLKSCKSSCVK 636
E+I +RL E K+ K L I EE LKE L IKS+ K + C +
Sbjct: 27 ELIGIPEDQRLQRTEVVKKHIK-ELLDMMIAEEESLKERL---IKSISVCQKELNTLCSE 82
Query: 637 LQVEMVGLTACLKAWKEHCRSEEGKTT-----KDLSIAVQVMKRIHSLMEKYSELLQEDD 691
L VE EEG+TT KDL V++M++ ++ +LLQE D
Sbjct: 83 LHVEPF--------------QEEGETTILQLEKDLRTQVELMRKQKKERKQELKLLQEQD 128
Query: 692 RQL 694
++L
Sbjct: 129 QEL 131
>gi|40807443 protein regulator of cytokinesis 1 isoform 2 [Homo
sapiens]
Length = 606
Score = 35.4 bits (80), Expect = 0.48
Identities = 39/123 (31%), Positives = 55/123 (44%), Gaps = 25/123 (20%)
Query: 579 EIIARENKKRLFAREEQKEEQKWNALSFSI--EEQLKENLHSGIKSLEDFLKSCKSSCVK 636
E+I +RL E K+ K L I EE LKE L IKS+ K + C +
Sbjct: 27 ELIGIPEDQRLQRTEVVKKHIK-ELLDMMIAEEESLKERL---IKSISVCQKELNTLCSE 82
Query: 637 LQVEMVGLTACLKAWKEHCRSEEGKTT-----KDLSIAVQVMKRIHSLMEKYSELLQEDD 691
L VE EEG+TT KDL V++M++ ++ +LLQE D
Sbjct: 83 LHVEPF--------------QEEGETTILQLEKDLRTQVELMRKQKKERKQELKLLQEQD 128
Query: 692 RQL 694
++L
Sbjct: 129 QEL 131
>gi|4506039 protein regulator of cytokinesis 1 isoform 1 [Homo
sapiens]
Length = 620
Score = 35.4 bits (80), Expect = 0.48
Identities = 39/123 (31%), Positives = 55/123 (44%), Gaps = 25/123 (20%)
Query: 579 EIIARENKKRLFAREEQKEEQKWNALSFSI--EEQLKENLHSGIKSLEDFLKSCKSSCVK 636
E+I +RL E K+ K L I EE LKE L IKS+ K + C +
Sbjct: 27 ELIGIPEDQRLQRTEVVKKHIK-ELLDMMIAEEESLKERL---IKSISVCQKELNTLCSE 82
Query: 637 LQVEMVGLTACLKAWKEHCRSEEGKTT-----KDLSIAVQVMKRIHSLMEKYSELLQEDD 691
L VE EEG+TT KDL V++M++ ++ +LLQE D
Sbjct: 83 LHVEPF--------------QEEGETTILQLEKDLRTQVELMRKQKKERKQELKLLQEQD 128
Query: 692 RQL 694
++L
Sbjct: 129 QEL 131
>gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo
sapiens]
Length = 820
Score = 35.0 bits (79), Expect = 0.63
Identities = 38/140 (27%), Positives = 65/140 (46%), Gaps = 16/140 (11%)
Query: 764 PDTWQRELLDVVDKNESAVIVAPTSSGKTYASYY-------CMEKV--LKESDDG-VVVY 813
P QR+ + + +N + VA T SGKT A + K+ ++ESD G +
Sbjct: 414 PTPIQRQAIPIGLQNRDIIGVAETGSGKTAAFLIPLLVWITTLPKIDRIEESDQGPYAII 473
Query: 814 VAPTKALVNQVAATVQNRFTKNLPSGEV-LCGVFTREYRHDAL--NCQVLITVPACFEIL 870
+APT+ L Q+ +F K L V + G +RE + L C+++I P ++
Sbjct: 474 LAPTRELAQQIEEET-IKFGKPLGIRTVAVIGGISREDQGFRLRMGCEIVIATPG--RLI 530
Query: 871 LLAPHRQNWVKKIRYVIFDE 890
+ +R + + YV+ DE
Sbjct: 531 DVLENRYLVLSRCTYVVLDE 550
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.136 0.405
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 63,389,779
Number of Sequences: 37866
Number of extensions: 2845500
Number of successful extensions: 8262
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 18
Number of HSP's successfully gapped in prelim test: 88
Number of HSP's that attempted gapping in prelim test: 8056
Number of HSP's gapped (non-prelim): 280
length of query: 1712
length of database: 18,247,518
effective HSP length: 116
effective length of query: 1596
effective length of database: 13,855,062
effective search space: 22112678952
effective search space used: 22112678952
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.