Search of human proteins with 22218345

Search of human proteins with 22218345

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|22218345 LAG1 homolog, ceramide synthase 5 [Homo sapiens]
         (392 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|22218345 LAG1 homolog, ceramide synthase 5 [Homo sapiens]          831   0.0  
gi|45007002 longevity assurance homolog 6 [Homo sapiens]              535   e-152
gi|205360977 LAG1 homolog, ceramide synthase 4 [Homo sapiens]         327   1e-89
gi|32455256 LAG1 longevity assurance 2 [Homo sapiens]                 323   2e-88
gi|31077094 LAG1 longevity assurance 2 [Homo sapiens]                 323   2e-88
gi|116235446 LAG1 longevity assurance homolog 3 [Homo sapiens]        305   4e-83
gi|38176296 LAG1 homolog, ceramide synthase 1 isoform 2 [Homo sa...    90   3e-18
gi|11641421 LAG1 homolog, ceramide synthase 1 isoform 1 [Homo sa...    90   3e-18
gi|7657655 translocation associated membrane protein 1 [Homo sap...    52   9e-07
gi|6912450 translocation-associated membrane protein 2 [Homo sap...    50   3e-06
gi|145580602 translocation associated membrane protein 1-like 1 ...    38   0.018
gi|183396780 ubiquitin specific protease 20 [Homo sapiens]             36   0.068
gi|183397136 ubiquitin specific protease 20 [Homo sapiens]             36   0.068
gi|183397134 ubiquitin specific protease 20 [Homo sapiens]             36   0.068
gi|55743092 aristaless-like homeobox 4 [Homo sapiens]                  32   0.76 
gi|12707580 paired-like homeobox 2b [Homo sapiens]                     32   0.76 
gi|46249382 paired-like homeobox 2a [Homo sapiens]                     32   0.76 
gi|194353946 homeobox D12 [Homo sapiens]                               32   0.99 
gi|113204604 aristaless-like homeobox 3 [Homo sapiens]                 32   0.99 
gi|6031203 short stature homeobox isoform SHOXb [Homo sapiens]         32   1.3  
gi|4506943 short stature homeobox isoform SHOXa [Homo sapiens]         32   1.3  
gi|89145413 short stature homeobox 2 isoform a [Homo sapiens]          32   1.3  
gi|87044888 short stature homeobox 2 isoform b [Homo sapiens]          32   1.3  
gi|27777663 goosecoid [Homo sapiens]                                   32   1.3  
gi|15619006 vasoactive intestinal peptide receptor 1 [Homo sapiens]    31   1.7  
gi|24497589 aristaless related homeobox [Homo sapiens]                 31   1.7  
gi|5902024 paired mesoderm homeobox 1 isoform pmx-1a [Homo sapiens]    31   2.2  
gi|12707577 paired mesoderm homeobox 1 isoform pmx-1b [Homo sapi...    31   2.2  
gi|122937321 UNC homeobox [Homo sapiens]                               31   2.2  
gi|30410785 LIM homeobox protein 1 [Homo sapiens]                      31   2.2  

>gi|22218345 LAG1 homolog, ceramide synthase 5 [Homo sapiens]
          Length = 392

 Score =  831 bits (2147), Expect = 0.0
 Identities = 392/392 (100%), Positives = 392/392 (100%)

Query: 1   MATAAQGPLSLLWGWLWSERFWLPENVSWADLEGPADGYGYPRGRHILSVFPLAAGIFFV 60
           MATAAQGPLSLLWGWLWSERFWLPENVSWADLEGPADGYGYPRGRHILSVFPLAAGIFFV
Sbjct: 1   MATAAQGPLSLLWGWLWSERFWLPENVSWADLEGPADGYGYPRGRHILSVFPLAAGIFFV 60

Query: 61  RLLFERFIAKPCALCIGIEDSGPYQAQPNAILEKVFISITKYPDKKRLEGLSKQLDWNVR 120
           RLLFERFIAKPCALCIGIEDSGPYQAQPNAILEKVFISITKYPDKKRLEGLSKQLDWNVR
Sbjct: 61  RLLFERFIAKPCALCIGIEDSGPYQAQPNAILEKVFISITKYPDKKRLEGLSKQLDWNVR 120

Query: 121 KIQCWFRHRRNQDKPPTLTKFCESMWRFTFYLCIFCYGIRFLWSSPWFWDIRQCWHNYPF 180
           KIQCWFRHRRNQDKPPTLTKFCESMWRFTFYLCIFCYGIRFLWSSPWFWDIRQCWHNYPF
Sbjct: 121 KIQCWFRHRRNQDKPPTLTKFCESMWRFTFYLCIFCYGIRFLWSSPWFWDIRQCWHNYPF 180

Query: 181 QPLSSGLYHYYIMELAFYWSLMFSQFTDIKRKDFLIMFVHHLVTIGLISFSYINNMVRVG 240
           QPLSSGLYHYYIMELAFYWSLMFSQFTDIKRKDFLIMFVHHLVTIGLISFSYINNMVRVG
Sbjct: 181 QPLSSGLYHYYIMELAFYWSLMFSQFTDIKRKDFLIMFVHHLVTIGLISFSYINNMVRVG 240

Query: 241 TLIMCLHDVSDFLLEAAKLANYAKYQRLCDTLFVIFSAVFMVTRLGIYPFWILNTTLFES 300
           TLIMCLHDVSDFLLEAAKLANYAKYQRLCDTLFVIFSAVFMVTRLGIYPFWILNTTLFES
Sbjct: 241 TLIMCLHDVSDFLLEAAKLANYAKYQRLCDTLFVIFSAVFMVTRLGIYPFWILNTTLFES 300

Query: 301 WEIIGPYASWWLLNGLLLTLQLLHVIWSYLIARIALKALIRGKVSKDDRSDVESSSEEED 360
           WEIIGPYASWWLLNGLLLTLQLLHVIWSYLIARIALKALIRGKVSKDDRSDVESSSEEED
Sbjct: 301 WEIIGPYASWWLLNGLLLTLQLLHVIWSYLIARIALKALIRGKVSKDDRSDVESSSEEED 360

Query: 361 VTTCTKSPCDSSSSNGANRVNGHMGGSYWAEE 392
           VTTCTKSPCDSSSSNGANRVNGHMGGSYWAEE
Sbjct: 361 VTTCTKSPCDSSSSNGANRVNGHMGGSYWAEE 392


>gi|45007002 longevity assurance homolog 6 [Homo sapiens]
          Length = 384

 Score =  535 bits (1377), Expect = e-152
 Identities = 241/370 (65%), Positives = 305/370 (82%), Gaps = 1/370 (0%)

Query: 15  WLWSERFWLPENVSWADLEGPADGYGYPRGRHILSVFPLAAGIFFVRLLFERFIAKPCAL 74
           W W+ERFWLP NV+WADL+   +   +P+   +   FPLA  IF VRL+FERF+AKPCA+
Sbjct: 7   WFWNERFWLPHNVTWADLKNTEEAT-FPQAEDLYLAFPLAFCIFMVRLIFERFVAKPCAI 65

Query: 75  CIGIEDSGPYQAQPNAILEKVFISITKYPDKKRLEGLSKQLDWNVRKIQCWFRHRRNQDK 134
            + I+ +GP  A PNAILEKVF +ITK+PD+KRLEGLSKQLDW+VR IQ WFR RRNQ+K
Sbjct: 66  ALNIQANGPQIAPPNAILEKVFTAITKHPDEKRLEGLSKQLDWDVRSIQRWFRQRRNQEK 125

Query: 135 PPTLTKFCESMWRFTFYLCIFCYGIRFLWSSPWFWDIRQCWHNYPFQPLSSGLYHYYIME 194
           P TLT+FCESMWRF+FYL +F YG+RFL  +PW W+ R CW+NYP+QPL++ L++YYI+E
Sbjct: 126 PSTLTRFCESMWRFSFYLYVFTYGVRFLKKTPWLWNTRHCWYNYPYQPLTTDLHYYYILE 185

Query: 195 LAFYWSLMFSQFTDIKRKDFLIMFVHHLVTIGLISFSYINNMVRVGTLIMCLHDVSDFLL 254
           L+FYWSLMFSQFTDIKRKDF IMF+HHLV+I LI+FSY+NNM RVGTL++CLHD +D LL
Sbjct: 186 LSFYWSLMFSQFTDIKRKDFGIMFLHHLVSIFLITFSYVNNMARVGTLVLCLHDSADALL 245

Query: 255 EAAKLANYAKYQRLCDTLFVIFSAVFMVTRLGIYPFWILNTTLFESWEIIGPYASWWLLN 314
           EAAK+ANYAK+Q++CD LFV+F+ VF+ TRLGI+P W+LNTTLFESWEI+GPY SWW+ N
Sbjct: 246 EAAKMANYAKFQKMCDLLFVMFAVVFITTRLGIFPLWVLNTTLFESWEIVGPYPSWWVFN 305

Query: 315 GLLLTLQLLHVIWSYLIARIALKALIRGKVSKDDRSDVESSSEEEDVTTCTKSPCDSSSS 374
            LLL +Q L+  WSYLI +IA KA+ RGKVSKDDRSD+ESSS+EED     K+P  ++++
Sbjct: 306 LLLLLVQGLNCFWSYLIVKIACKAVSRGKVSKDDRSDIESSSDEEDSEPPGKNPHTATTT 365

Query: 375 NGANRVNGHM 384
           NG +  NG++
Sbjct: 366 NGTSGTNGYL 375


>gi|205360977 LAG1 homolog, ceramide synthase 4 [Homo sapiens]
          Length = 394

 Score =  327 bits (838), Expect = 1e-89
 Identities = 159/346 (45%), Positives = 217/346 (62%), Gaps = 1/346 (0%)

Query: 15  WLWSERFWLPENVSWADLEGPADGYGYPRGRHILSVFPLAAGIFFVRLLFERFIAKPCAL 74
           W W +RFWLP NV+W +LE   DG  YP  + +L+  PLA  +  +RL FERFI  P + 
Sbjct: 8   WFWQDRFWLPPNVTWTELED-RDGRVYPHPQDLLAALPLALVLLAMRLAFERFIGLPLSR 66

Query: 75  CIGIEDSGPYQAQPNAILEKVFISITKYPDKKRLEGLSKQLDWNVRKIQCWFRHRRNQDK 134
            +G+ D    Q +PNA LEK F++    P + +L  L+ Q    +++ Q WFR RRNQD+
Sbjct: 67  WLGVRDQTRRQVKPNATLEKHFLTEGHRPKEPQLSLLAAQCGLTLQQTQRWFRRRRNQDR 126

Query: 135 PPTLTKFCESMWRFTFYLCIFCYGIRFLWSSPWFWDIRQCWHNYPFQPLSSGLYHYYIME 194
           P    KFCE+ WRF FYL  F  G+  L+   W W    CW  YP Q L   LY +Y++E
Sbjct: 127 PQLTKKFCEASWRFLFYLSSFVGGLSVLYHESWLWAPVMCWDRYPNQTLKPSLYWWYLLE 186

Query: 195 LAFYWSLMFSQFTDIKRKDFLIMFVHHLVTIGLISFSYINNMVRVGTLIMCLHDVSDFLL 254
           L FY SL+     D+KRKDF    +HH V + L++FSY  N++R+G+L++ LHD SD+LL
Sbjct: 187 LGFYLSLLIRLPFDVKRKDFKEQVIHHFVAVILMTFSYSANLLRIGSLVLLLHDSSDYLL 246

Query: 255 EAAKLANYAKYQRLCDTLFVIFSAVFMVTRLGIYPFWILNTTLFESWEIIGPYASWWLLN 314
           EA K+ NY +YQ++CD LF+IFS VF  TRL ++P  IL TT +ES    GP+  ++  N
Sbjct: 247 EACKMVNYMQYQQVCDALFLIFSFVFFYTRLVLFPTQILYTTYYESISNRGPFFGYYFFN 306

Query: 315 GLLLTLQLLHVIWSYLIARIALKALIRGKVSKDDRSDVESSSEEED 360
           GLL+ LQLLHV WS LI R+    + +G++ KD RSDVE S   E+
Sbjct: 307 GLLMLLQLLHVFWSCLILRMLYSFMKKGQMEKDIRSDVEESDSSEE 352


>gi|32455256 LAG1 longevity assurance 2 [Homo sapiens]
          Length = 380

 Score =  323 bits (828), Expect = 2e-88
 Identities = 157/351 (44%), Positives = 223/351 (63%), Gaps = 2/351 (0%)

Query: 9   LSLLWGWLWSERFWLPENVSWADLEGPADGYGYPRGRHILSVFPLAAGIFFVRLLFERFI 68
           L  L+ + W ER WLP N++WADLE   DG  Y +   +    PLA     VR  FE ++
Sbjct: 2   LQTLYDYFWWERLWLPVNLTWADLED-RDGRVYAKASDLYITLPLALLFLIVRYFFELYV 60

Query: 69  AKPCALCIGIEDSGPYQAQPNAILEKVFISITKYPDKKRLEGLSKQLDWNVRKIQCWFRH 128
           A P A  + I++    +A PNA LE  +++  K P +  +E LS+Q   + R+++ WFR 
Sbjct: 61  ATPLAALLNIKEKTRLRAPPNATLEHFYLTSGKQPKQVEVELLSRQSGLSGRQVERWFRR 120

Query: 129 RRNQDKPPTLTKFCESMWRFTFYLCIFCYGIRFLWSSPWFWDIRQCWHNYPFQPLSSGLY 188
           RRNQD+P  L KF E+ WRFTFYL  F  G+  +   PWF+D+++ W  YP Q      Y
Sbjct: 121 RRNQDRPSLLKKFREASWRFTFYLIAFIAGMAVIVDKPWFYDMKKVWEGYPIQSTIPSQY 180

Query: 189 HYYIMELAFYWSLMFSQFTDIKRKDFLIMFVHHLVTIGLISFSYINNMVRVGTLIMCLHD 248
            YY++EL+FYWSL+FS  +D+KRKDF    +HH+ TI LISFS+  N +R GTLIM LHD
Sbjct: 181 WYYMIELSFYWSLLFSIASDVKRKDFKEQIIHHVATIILISFSWFANYIRAGTLIMALHD 240

Query: 249 VSDFLLEAAKLANYAKYQRLCDTLFVIFSAVFMVTRLGIYPFWILNTTLFESWEIIGPYA 308
            SD+LLE+AK+ NYA ++  C+ +F++F+ VF++TRL I PFWIL+ TL    E+   + 
Sbjct: 241 SSDYLLESAKMFNYAGWKNTCNNIFIVFAIVFIITRLVILPFWILHCTLVYPLELYPAFF 300

Query: 309 SWWLLNGLLLTLQLLHVIWSYLIARIALKALIRGKVSKDDRSDVESSSEEE 359
            ++  N ++  LQLLH+ W+YLI R+A K  I GK+ +D+RSD E +   E
Sbjct: 301 GYYFFNSMMGVLQLLHIFWAYLILRMAHK-FITGKLVEDERSDREETESSE 350


>gi|31077094 LAG1 longevity assurance 2 [Homo sapiens]
          Length = 380

 Score =  323 bits (828), Expect = 2e-88
 Identities = 157/351 (44%), Positives = 223/351 (63%), Gaps = 2/351 (0%)

Query: 9   LSLLWGWLWSERFWLPENVSWADLEGPADGYGYPRGRHILSVFPLAAGIFFVRLLFERFI 68
           L  L+ + W ER WLP N++WADLE   DG  Y +   +    PLA     VR  FE ++
Sbjct: 2   LQTLYDYFWWERLWLPVNLTWADLED-RDGRVYAKASDLYITLPLALLFLIVRYFFELYV 60

Query: 69  AKPCALCIGIEDSGPYQAQPNAILEKVFISITKYPDKKRLEGLSKQLDWNVRKIQCWFRH 128
           A P A  + I++    +A PNA LE  +++  K P +  +E LS+Q   + R+++ WFR 
Sbjct: 61  ATPLAALLNIKEKTRLRAPPNATLEHFYLTSGKQPKQVEVELLSRQSGLSGRQVERWFRR 120

Query: 129 RRNQDKPPTLTKFCESMWRFTFYLCIFCYGIRFLWSSPWFWDIRQCWHNYPFQPLSSGLY 188
           RRNQD+P  L KF E+ WRFTFYL  F  G+  +   PWF+D+++ W  YP Q      Y
Sbjct: 121 RRNQDRPSLLKKFREASWRFTFYLIAFIAGMAVIVDKPWFYDMKKVWEGYPIQSTIPSQY 180

Query: 189 HYYIMELAFYWSLMFSQFTDIKRKDFLIMFVHHLVTIGLISFSYINNMVRVGTLIMCLHD 248
            YY++EL+FYWSL+FS  +D+KRKDF    +HH+ TI LISFS+  N +R GTLIM LHD
Sbjct: 181 WYYMIELSFYWSLLFSIASDVKRKDFKEQIIHHVATIILISFSWFANYIRAGTLIMALHD 240

Query: 249 VSDFLLEAAKLANYAKYQRLCDTLFVIFSAVFMVTRLGIYPFWILNTTLFESWEIIGPYA 308
            SD+LLE+AK+ NYA ++  C+ +F++F+ VF++TRL I PFWIL+ TL    E+   + 
Sbjct: 241 SSDYLLESAKMFNYAGWKNTCNNIFIVFAIVFIITRLVILPFWILHCTLVYPLELYPAFF 300

Query: 309 SWWLLNGLLLTLQLLHVIWSYLIARIALKALIRGKVSKDDRSDVESSSEEE 359
            ++  N ++  LQLLH+ W+YLI R+A K  I GK+ +D+RSD E +   E
Sbjct: 301 GYYFFNSMMGVLQLLHIFWAYLILRMAHK-FITGKLVEDERSDREETESSE 350


>gi|116235446 LAG1 longevity assurance homolog 3 [Homo sapiens]
          Length = 383

 Score =  305 bits (782), Expect = 4e-83
 Identities = 151/346 (43%), Positives = 216/346 (62%), Gaps = 3/346 (0%)

Query: 15  WLWSERFWLPENVSWADLEGPADGYGYPRGRHILSVFPLAAGIFFVRLLFERFIAKPCAL 74
           W W ERFWLP  + W+DLE   DG  + +  H+    P A  +  +R +FE+F+A P A 
Sbjct: 8   WFWLERFWLPPTIKWSDLEDH-DGLVFVKPSHLYVTIPYAFLLLIIRRVFEKFVASPLAK 66

Query: 75  CIGIEDSGPYQAQPNAILEKVFISITKYPDKKRLEGLSKQLDWNVRKIQCWFRHRRNQDK 134
             GI+++   +  PN +LE  F   T+ P +  + GL+K+ +   R+++ WFR RRNQ++
Sbjct: 67  SFGIKET-VRKVTPNTVLENFFKHSTRQPLQTDIYGLAKKCNLTERQVERWFRSRRNQER 125

Query: 135 PPTLTKFCESMWRFTFYLCIFCYGIRFLWSSPWFWDIRQCWHNYPFQPLSSGLYHYYIME 194
           P  L KF E+ WRF FYL I   GI FL+  PW +D+ + W+ YP QPL    Y YYI+E
Sbjct: 126 PSRLKKFQEACWRFAFYLMITVAGIAFLYDKPWLYDLWEVWNGYPKQPLLPSQYWYYILE 185

Query: 195 LAFYWSLMFSQFTDIKRKDFLIMFVHHLVTIGLISFSYINNMVRVGTLIMCLHDVSDFLL 254
           ++FYWSL+F    D+KRKDFL   +HHL  I L+SFS+  N +R GTL+M +HDV+D  L
Sbjct: 186 MSFYWSLLFRLGFDVKRKDFLAHIIHHLAAISLMSFSWCANYIRSGTLVMIVHDVADIWL 245

Query: 255 EAAKLANYAKYQRLCDTLFVIFSAVFMVTRLGIYPFWILNTTLFESWEIIGPYASWWLLN 314
           E+AK+ +YA + + C+TLF IFS +F ++RL ++PFWIL  TL      + P+ S+  LN
Sbjct: 246 ESAKMFSYAGWTQTCNTLFFIFSTIFFISRLIVFPFWILYCTLILPMYHLEPFFSYIFLN 305

Query: 315 GLLLTLQLLHVIWSYLIARIALKALIRGKVSKDDRSDVESSSEEED 360
             L+ LQ+LH+ W Y I ++ L   I  K  +D RSD E   EEE+
Sbjct: 306 LQLMILQVLHLYWGYYILKM-LNRCIFMKSIQDVRSDDEDYEEEEE 350


>gi|38176296 LAG1 homolog, ceramide synthase 1 isoform 2 [Homo
           sapiens]
          Length = 337

 Score = 90.1 bits (222), Expect = 3e-18
 Identities = 68/219 (31%), Positives = 105/219 (47%), Gaps = 13/219 (5%)

Query: 134 KPPTLTKFCESMWRFTFYLCIFCYGIRFLWSS--PWFWDIRQCWHNY-PFQPLSSGLYHY 190
           +P    K  ES W+F FYL  + Y    L+ +  P+F D    ++++ P   +   +   
Sbjct: 92  QPRDAAKMPESAWKFLFYLGSWSYSAYLLFGTDYPFFHDPPSVFYDWTPGMAVPRDIAAA 151

Query: 191 YIMELAFYW-SLMFSQFTDIKRKDFLIMFVHHLVTIGLISFSYINNMVRVGTLIMCLHDV 249
           Y+++ +FY  S+  + + D  RKD ++M +HH+VT+ LI  SY      VG L++ LHD+
Sbjct: 152 YLLQGSFYGHSIYATLYMDTWRKDSVVMLLHHVVTLILIVSSYAFRYHNVGILVLFLHDI 211

Query: 250 SDFLLEAAKLANYAK-----YQRL----CDTLFVIFSAVFMVTRLGIYPFWILNTTLFES 300
           SD  LE  KL  Y K     Y RL     D   + F   +   RL  +P  +L  T   S
Sbjct: 212 SDVQLEFTKLNIYFKSRGGSYHRLHALAADLGCLSFGFSWFWFRLYWFPLKVLYATSHCS 271

Query: 301 WEIIGPYASWWLLNGLLLTLQLLHVIWSYLIARIALKAL 339
              +     ++  N LLL L L+++ W   I   A K L
Sbjct: 272 LRTVPDIPFYFFFNALLLLLTLMNLYWFLYIVAFAAKVL 310


>gi|11641421 LAG1 homolog, ceramide synthase 1 isoform 1 [Homo
           sapiens]
          Length = 350

 Score = 90.1 bits (222), Expect = 3e-18
 Identities = 68/219 (31%), Positives = 105/219 (47%), Gaps = 13/219 (5%)

Query: 134 KPPTLTKFCESMWRFTFYLCIFCYGIRFLWSS--PWFWDIRQCWHNY-PFQPLSSGLYHY 190
           +P    K  ES W+F FYL  + Y    L+ +  P+F D    ++++ P   +   +   
Sbjct: 92  QPRDAAKMPESAWKFLFYLGSWSYSAYLLFGTDYPFFHDPPSVFYDWTPGMAVPRDIAAA 151

Query: 191 YIMELAFYW-SLMFSQFTDIKRKDFLIMFVHHLVTIGLISFSYINNMVRVGTLIMCLHDV 249
           Y+++ +FY  S+  + + D  RKD ++M +HH+VT+ LI  SY      VG L++ LHD+
Sbjct: 152 YLLQGSFYGHSIYATLYMDTWRKDSVVMLLHHVVTLILIVSSYAFRYHNVGILVLFLHDI 211

Query: 250 SDFLLEAAKLANYAK-----YQRL----CDTLFVIFSAVFMVTRLGIYPFWILNTTLFES 300
           SD  LE  KL  Y K     Y RL     D   + F   +   RL  +P  +L  T   S
Sbjct: 212 SDVQLEFTKLNIYFKSRGGSYHRLHALAADLGCLSFGFSWFWFRLYWFPLKVLYATSHCS 271

Query: 301 WEIIGPYASWWLLNGLLLTLQLLHVIWSYLIARIALKAL 339
              +     ++  N LLL L L+++ W   I   A K L
Sbjct: 272 LRTVPDIPFYFFFNALLLLLTLMNLYWFLYIVAFAAKVL 310


>gi|7657655 translocation associated membrane protein 1 [Homo
           sapiens]
          Length = 374

 Score = 52.0 bits (123), Expect = 9e-07
 Identities = 45/155 (29%), Positives = 75/155 (48%), Gaps = 17/155 (10%)

Query: 139 TKFCESMWRFTFYLCIFCYGIRFLWSSPWFWDIRQCWHNYPFQPLSSGLYHYYIMELAFY 198
           +KF ES     FYL    +G   L S  +  D    W  YP   ++  +  +YI +LA Y
Sbjct: 117 SKFNESGQLSAFYLFACVWGTFILISENYISDPTILWRAYPHNLMTFQMKFFYISQLA-Y 175

Query: 199 WSLMFSQ--FTDIKRKDFLIMFVHHLVTIGLISF----SYINNMVRVGTLIMCLHDVSDF 252
           W   F +  F   K++D        LV IGL  F    +Y+ N+  +G +++ LH   +F
Sbjct: 176 WLHAFPELYFQKTKKED----IPRQLVYIGLYLFHIAGAYLLNLNHLGLVLLVLHYFVEF 231

Query: 253 LLEAAKLANYA--KYQRLCDTLFVIFSAVFMVTRL 285
           L   ++L  ++  KYQ+     F +++ +F++ RL
Sbjct: 232 LFHISRLFYFSNEKYQK----GFSLWAVLFVLGRL 262


>gi|6912450 translocation-associated membrane protein 2 [Homo
           sapiens]
          Length = 370

 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 42/159 (26%), Positives = 81/159 (50%), Gaps = 9/159 (5%)

Query: 139 TKFCES--MWRFTFYLCIFCYGIRFLWSSPWFWDIRQCWHNYPFQPLSSGLYHYYIMELA 196
           +KF ES  +  F F   I+C+ +  + +  +  + R  W +YP   L   +  +Y+ +LA
Sbjct: 112 SKFNESGQLVVFHFTSVIWCFYV--VVTEGYLTNPRSLWEDYPHVHLPFQVKFFYLCQLA 169

Query: 197 FYW--SLMFSQFTDIKRKDFLIMFVHHLVTIGLISFSYINNMVRVGTLIMCLHDVSDFLL 254
            YW  +L    F  +++++      +  + +  I+ +Y+ N+ R+G +++ L   ++FL 
Sbjct: 170 -YWLHALPELYFQKVRKEEIPRQLQYICLYLVHIAGAYLLNLSRLGLILLLLQYSTEFLF 228

Query: 255 EAAKLANYAKYQRLCDTLFVIFSAVFMVTRLGIYPFWIL 293
             A+L  +A      + LF  ++AVF VTRL I    +L
Sbjct: 229 HTARLFYFADENN--EKLFSAWAAVFGVTRLFILTLAVL 265


>gi|145580602 translocation associated membrane protein 1-like 1
           [Homo sapiens]
          Length = 369

 Score = 37.7 bits (86), Expect = 0.018
 Identities = 39/160 (24%), Positives = 67/160 (41%), Gaps = 5/160 (3%)

Query: 128 HRRNQDKPPTLTKFCESMWRFTFYLCIFCYGIRFLWSSPWFWDIRQCWHNYPFQPLSSGL 187
           ++R Q       KF ES     FY     +G   L S     D    W   P   ++  +
Sbjct: 106 NKRMQFTKAKQNKFNESGQFSVFYFFSCIWGTFILISENCLSDPTLIWKARPHSMMTFQM 165

Query: 188 YHYYIMELAFYWSLMFSQ--FTDIKRKDFLIMFVHHLVTIGLISFSYINNMVRVGTLIMC 245
             +YI +LA YW   F +  F   K++D     V+  + +  I+ +Y+  +  +G L++ 
Sbjct: 166 KFFYISQLA-YWFHAFPELYFQKTKKQDIPRQLVYIGLHLFHITGAYLLYLNHLGLLLLV 224

Query: 246 LHDVSDFLLEAAKLANYA--KYQRLCDTLFVIFSAVFMVT 283
           LH   + L     L  ++  KYQ+      ++F    +VT
Sbjct: 225 LHYFVELLSHMCGLFYFSDEKYQKGISLWAIVFILGRLVT 264


>gi|183396780 ubiquitin specific protease 20 [Homo sapiens]
          Length = 914

 Score = 35.8 bits (81), Expect = 0.068
 Identities = 42/175 (24%), Positives = 71/175 (40%), Gaps = 18/175 (10%)

Query: 226 GLISFSYINNMVRVGTLIMCLHD---VSDFLLEAAKLANYAKYQRLCDTLFVIFSAVFMV 282
           GL     + N   +   +  L +   ++ F LE   L    K   LC +   + S V+  
Sbjct: 143 GLTGMKNLGNSCYMNAALQALSNCPPLTQFFLECGGLVRTDKKPALCKSYQKLVSEVWHK 202

Query: 283 TRLGIYPFWILNTTLFESWEIIGP----YASWWLLNGLLLTLQLLHV-IWSYLIARIAL- 336
            R    P +++ T+L    +++ P    YA       L   +  LH  +   ++A +AL 
Sbjct: 203 KR----PSYVVPTSLSHGIKLVNPMFRGYAQQDTQEFLRCLMDQLHEELKEPVVATVALT 258

Query: 337 KALIRGKVSKDDRSDVESSSEEEDVTTCTKSPCDSSSSNGANRVNGHMGGSYWAE 391
           +A        D++ + + S  E++  +C     DSSS  G     G  GGS  AE
Sbjct: 259 EARDSDSSDTDEKREGDRSPSEDEFLSC-----DSSSDRGEGDGQGRGGGSSQAE 308


>gi|183397136 ubiquitin specific protease 20 [Homo sapiens]
          Length = 914

 Score = 35.8 bits (81), Expect = 0.068
 Identities = 42/175 (24%), Positives = 71/175 (40%), Gaps = 18/175 (10%)

Query: 226 GLISFSYINNMVRVGTLIMCLHD---VSDFLLEAAKLANYAKYQRLCDTLFVIFSAVFMV 282
           GL     + N   +   +  L +   ++ F LE   L    K   LC +   + S V+  
Sbjct: 143 GLTGMKNLGNSCYMNAALQALSNCPPLTQFFLECGGLVRTDKKPALCKSYQKLVSEVWHK 202

Query: 283 TRLGIYPFWILNTTLFESWEIIGP----YASWWLLNGLLLTLQLLHV-IWSYLIARIAL- 336
            R    P +++ T+L    +++ P    YA       L   +  LH  +   ++A +AL 
Sbjct: 203 KR----PSYVVPTSLSHGIKLVNPMFRGYAQQDTQEFLRCLMDQLHEELKEPVVATVALT 258

Query: 337 KALIRGKVSKDDRSDVESSSEEEDVTTCTKSPCDSSSSNGANRVNGHMGGSYWAE 391
           +A        D++ + + S  E++  +C     DSSS  G     G  GGS  AE
Sbjct: 259 EARDSDSSDTDEKREGDRSPSEDEFLSC-----DSSSDRGEGDGQGRGGGSSQAE 308


>gi|183397134 ubiquitin specific protease 20 [Homo sapiens]
          Length = 914

 Score = 35.8 bits (81), Expect = 0.068
 Identities = 42/175 (24%), Positives = 71/175 (40%), Gaps = 18/175 (10%)

Query: 226 GLISFSYINNMVRVGTLIMCLHD---VSDFLLEAAKLANYAKYQRLCDTLFVIFSAVFMV 282
           GL     + N   +   +  L +   ++ F LE   L    K   LC +   + S V+  
Sbjct: 143 GLTGMKNLGNSCYMNAALQALSNCPPLTQFFLECGGLVRTDKKPALCKSYQKLVSEVWHK 202

Query: 283 TRLGIYPFWILNTTLFESWEIIGP----YASWWLLNGLLLTLQLLHV-IWSYLIARIAL- 336
            R    P +++ T+L    +++ P    YA       L   +  LH  +   ++A +AL 
Sbjct: 203 KR----PSYVVPTSLSHGIKLVNPMFRGYAQQDTQEFLRCLMDQLHEELKEPVVATVALT 258

Query: 337 KALIRGKVSKDDRSDVESSSEEEDVTTCTKSPCDSSSSNGANRVNGHMGGSYWAE 391
           +A        D++ + + S  E++  +C     DSSS  G     G  GGS  AE
Sbjct: 259 EARDSDSSDTDEKREGDRSPSEDEFLSC-----DSSSDRGEGDGQGRGGGSSQAE 308


>gi|55743092 aristaless-like homeobox 4 [Homo sapiens]
          Length = 411

 Score = 32.3 bits (72), Expect = 0.76
 Identities = 17/39 (43%), Positives = 23/39 (58%), Gaps = 1/39 (2%)

Query: 92  LEKVFISITKYPDKKRLEGLSKQLDWNVRKIQCWFRHRR 130
           LEKVF   T YPD    E L+ + D    ++Q WF++RR
Sbjct: 229 LEKVFQK-THYPDVYAREQLAMRTDLTEARVQVWFQNRR 266


>gi|12707580 paired-like homeobox 2b [Homo sapiens]
          Length = 314

 Score = 32.3 bits (72), Expect = 0.76
 Identities = 16/39 (41%), Positives = 24/39 (61%), Gaps = 1/39 (2%)

Query: 92  LEKVFISITKYPDKKRLEGLSKQLDWNVRKIQCWFRHRR 130
           LE+VF   T YPD    E L+ ++D    ++Q WF++RR
Sbjct: 113 LERVFAE-THYPDIYTREELALKIDLTEARVQVWFQNRR 150


>gi|46249382 paired-like homeobox 2a [Homo sapiens]
          Length = 284

 Score = 32.3 bits (72), Expect = 0.76
 Identities = 16/39 (41%), Positives = 24/39 (61%), Gaps = 1/39 (2%)

Query: 92  LEKVFISITKYPDKKRLEGLSKQLDWNVRKIQCWFRHRR 130
           LE+VF   T YPD    E L+ ++D    ++Q WF++RR
Sbjct: 105 LERVFAE-THYPDIYTREELALKIDLTEARVQVWFQNRR 142


>gi|194353946 homeobox D12 [Homo sapiens]
          Length = 270

 Score = 32.0 bits (71), Expect = 0.99
 Identities = 15/52 (28%), Positives = 34/52 (65%), Gaps = 1/52 (1%)

Query: 83  PYQAQPNAILEKVFISITKYPDKKRLEGLSKQLDWNVRKIQCWFRHRRNQDK 134
           PY  Q  A LE  F+ + ++ ++++ + LS +L+ + ++++ WF++RR + K
Sbjct: 208 PYTKQQIAELENEFL-VNEFINRQKRKELSNRLNLSDQQVKIWFQNRRMKKK 258


>gi|113204604 aristaless-like homeobox 3 [Homo sapiens]
          Length = 343

 Score = 32.0 bits (71), Expect = 0.99
 Identities = 17/39 (43%), Positives = 23/39 (58%), Gaps = 1/39 (2%)

Query: 92  LEKVFISITKYPDKKRLEGLSKQLDWNVRKIQCWFRHRR 130
           LEKVF   T YPD    E L+ + D    ++Q WF++RR
Sbjct: 168 LEKVFQK-THYPDVYAREQLALRTDLTEARVQVWFQNRR 205


>gi|6031203 short stature homeobox isoform SHOXb [Homo sapiens]
          Length = 225

 Score = 31.6 bits (70), Expect = 1.3
 Identities = 16/39 (41%), Positives = 25/39 (64%), Gaps = 1/39 (2%)

Query: 92  LEKVFISITKYPDKKRLEGLSKQLDWNVRKIQCWFRHRR 130
           LE++F   T YPD    E LS++L  +  ++Q WF++RR
Sbjct: 132 LERLFDE-THYPDAFMREELSQRLGLSEARVQVWFQNRR 169


>gi|4506943 short stature homeobox isoform SHOXa [Homo sapiens]
          Length = 292

 Score = 31.6 bits (70), Expect = 1.3
 Identities = 16/39 (41%), Positives = 25/39 (64%), Gaps = 1/39 (2%)

Query: 92  LEKVFISITKYPDKKRLEGLSKQLDWNVRKIQCWFRHRR 130
           LE++F   T YPD    E LS++L  +  ++Q WF++RR
Sbjct: 132 LERLFDE-THYPDAFMREELSQRLGLSEARVQVWFQNRR 169


>gi|89145413 short stature homeobox 2 isoform a [Homo sapiens]
          Length = 331

 Score = 31.6 bits (70), Expect = 1.3
 Identities = 16/39 (41%), Positives = 25/39 (64%), Gaps = 1/39 (2%)

Query: 92  LEKVFISITKYPDKKRLEGLSKQLDWNVRKIQCWFRHRR 130
           LE++F   T YPD    E LS++L  +  ++Q WF++RR
Sbjct: 155 LERLFDE-THYPDAFMREELSQRLGLSEARVQVWFQNRR 192


>gi|87044888 short stature homeobox 2 isoform b [Homo sapiens]
          Length = 190

 Score = 31.6 bits (70), Expect = 1.3
 Identities = 16/39 (41%), Positives = 25/39 (64%), Gaps = 1/39 (2%)

Query: 92  LEKVFISITKYPDKKRLEGLSKQLDWNVRKIQCWFRHRR 130
           LE++F   T YPD    E LS++L  +  ++Q WF++RR
Sbjct: 26  LERLFDE-THYPDAFMREELSQRLGLSEARVQVWFQNRR 63


>gi|27777663 goosecoid [Homo sapiens]
          Length = 257

 Score = 31.6 bits (70), Expect = 1.3
 Identities = 15/39 (38%), Positives = 24/39 (61%), Gaps = 1/39 (2%)

Query: 92  LEKVFISITKYPDKKRLEGLSKQLDWNVRKIQCWFRHRR 130
           LE +F   TKYPD    E L++++     K++ WF++RR
Sbjct: 175 LENLFQE-TKYPDVGTREQLARKVHLREEKVEVWFKNRR 212


>gi|15619006 vasoactive intestinal peptide receptor 1 [Homo sapiens]
          Length = 457

 Score = 31.2 bits (69), Expect = 1.7
 Identities = 20/63 (31%), Positives = 30/63 (47%), Gaps = 4/63 (6%)

Query: 291 WILNTTLFES---WEIIGPYASWWLLNGLLLTLQLLHVIWSYLIARIALKALIRGKVSKD 347
           W +    FE    W+ I   + WW++ G +LT  L++ I    I RI L+ L    + K 
Sbjct: 273 WTIARIHFEDYGCWDTINS-SLWWIIKGPILTSILVNFILFICIIRILLQKLRPPDIRKS 331

Query: 348 DRS 350
           D S
Sbjct: 332 DSS 334


>gi|24497589 aristaless related homeobox [Homo sapiens]
          Length = 562

 Score = 31.2 bits (69), Expect = 1.7
 Identities = 16/39 (41%), Positives = 23/39 (58%), Gaps = 1/39 (2%)

Query: 92  LEKVFISITKYPDKKRLEGLSKQLDWNVRKIQCWFRHRR 130
           LE+ F   T YPD    E L+ +LD    ++Q WF++RR
Sbjct: 343 LERAFQK-THYPDVFTREELAMRLDLTEARVQVWFQNRR 380


>gi|5902024 paired mesoderm homeobox 1 isoform pmx-1a [Homo sapiens]
          Length = 217

 Score = 30.8 bits (68), Expect = 2.2
 Identities = 15/39 (38%), Positives = 25/39 (64%), Gaps = 1/39 (2%)

Query: 92  LEKVFISITKYPDKKRLEGLSKQLDWNVRKIQCWFRHRR 130
           LE+VF   T YPD    E L+++++    ++Q WF++RR
Sbjct: 109 LERVF-ERTHYPDAFVREDLARRVNLTEARVQVWFQNRR 146


>gi|12707577 paired mesoderm homeobox 1 isoform pmx-1b [Homo
           sapiens]
          Length = 245

 Score = 30.8 bits (68), Expect = 2.2
 Identities = 15/39 (38%), Positives = 25/39 (64%), Gaps = 1/39 (2%)

Query: 92  LEKVFISITKYPDKKRLEGLSKQLDWNVRKIQCWFRHRR 130
           LE+VF   T YPD    E L+++++    ++Q WF++RR
Sbjct: 109 LERVF-ERTHYPDAFVREDLARRVNLTEARVQVWFQNRR 146


>gi|122937321 UNC homeobox [Homo sapiens]
          Length = 531

 Score = 30.8 bits (68), Expect = 2.2
 Identities = 18/49 (36%), Positives = 28/49 (57%), Gaps = 1/49 (2%)

Query: 92  LEKVFISITKYPDKKRLEGLSKQLDWNVRKIQCWFRHRRNQDKPPTLTK 140
           LEK F + + YPD    E L+ +LD    ++Q WF++RR + +    TK
Sbjct: 120 LEKAF-NESHYPDVFMREALALRLDLVESRVQVWFQNRRAKWRKKENTK 167


>gi|30410785 LIM homeobox protein 1 [Homo sapiens]
          Length = 406

 Score = 30.8 bits (68), Expect = 2.2
 Identities = 18/61 (29%), Positives = 32/61 (52%), Gaps = 2/61 (3%)

Query: 76  IGIEDSGPYQAQPNAILE--KVFISITKYPDKKRLEGLSKQLDWNVRKIQCWFRHRRNQD 133
           +G +  GP        LE  K   + T  P +   E L+++   N+R IQ WF++RR+++
Sbjct: 176 LGAKRRGPRTTIKAKQLETLKAAFAATPKPTRHIREQLAQETGLNMRVIQVWFQNRRSKE 235

Query: 134 K 134
           +
Sbjct: 236 R 236


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.327    0.141    0.480 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,506,702
Number of Sequences: 37866
Number of extensions: 670426
Number of successful extensions: 2255
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 25
Number of HSP's successfully gapped in prelim test: 26
Number of HSP's that attempted gapping in prelim test: 2212
Number of HSP's gapped (non-prelim): 54
length of query: 392
length of database: 18,247,518
effective HSP length: 104
effective length of query: 288
effective length of database: 14,309,454
effective search space: 4121122752
effective search space used: 4121122752
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.