Guide to the Human Genome
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Search of human proteins with 221136973

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|221136973 SLIT and NTRK-like family, member 2 [Homo sapiens]
         (845 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|221136985 SLIT and NTRK-like family, member 2 [Homo sapiens]      1712   0.0  
gi|221136981 SLIT and NTRK-like family, member 2 [Homo sapiens]      1712   0.0  
gi|221136977 SLIT and NTRK-like family, member 2 [Homo sapiens]      1712   0.0  
gi|221136973 SLIT and NTRK-like family, member 2 [Homo sapiens]      1712   0.0  
gi|221136969 SLIT and NTRK-like family, member 2 [Homo sapiens]      1712   0.0  
gi|221136965 SLIT and NTRK-like family, member 2 [Homo sapiens]      1712   0.0  
gi|221136961 SLIT and NTRK-like family, member 2 [Homo sapiens]      1712   0.0  
gi|221136957 SLIT and NTRK-like family, member 2 [Homo sapiens]      1712   0.0  
gi|33504581 SLIT and NTRK-like family, member 2 [Homo sapiens]       1712   0.0  
gi|40217823 SLIT and NTRK-like family, member 5 [Homo sapiens]        799   0.0  
gi|27436867 slit and trk like 4 protein [Homo sapiens]                656   0.0  
gi|40217820 slit and trk like 3 protein [Homo sapiens]                652   0.0  
gi|40217825 slit and trk like 6 [Homo sapiens]                        587   e-167
gi|40217817 slit and trk like 1 protein [Homo sapiens]                544   e-154
gi|188528675 slit homolog 1 [Homo sapiens]                            146   9e-35
gi|4759146 slit homolog 2 [Homo sapiens]                              134   5e-31
gi|11321571 slit homolog 3 [Homo sapiens]                             132   1e-30
gi|194440719 chondroadherin-like [Homo sapiens]                       125   2e-28
gi|13194201 reticulon 4 receptor precursor [Homo sapiens]             105   1e-22
gi|205277468 leucine rich repeat containing 15 isoform a [Homo s...   105   2e-22
gi|18677767 leucine rich repeat containing 15 isoform b [Homo sa...   105   2e-22
gi|30425563 reticulon 4 receptor-like 2 [Homo sapiens]                100   4e-21
gi|198041768 synleurin [Homo sapiens]                                  99   1e-20
gi|34577057 fibronectin leucine rich transmembrane protein 1 [Ho...    96   1e-19
gi|38202222 fibronectin leucine rich transmembrane protein 3 pre...    96   1e-19
gi|7019383 fibronectin leucine rich transmembrane protein 3 prec...    96   1e-19
gi|153251229 chondroadherin precursor [Homo sapiens]                   96   2e-19
gi|10190722 leucine-rich repeats and transmembrane domains 1 [Ho...    93   9e-19
gi|84781739 leucine-rich repeats and transmembrane domains 2 [Ho...    92   3e-18
gi|30425553 reticulon 4 receptor-like 1 [Homo sapiens]                 92   3e-18

>gi|221136985 SLIT and NTRK-like family, member 2 [Homo sapiens]
          Length = 845

 Score = 1712 bits (4435), Expect = 0.0
 Identities = 845/845 (100%), Positives = 845/845 (100%)

Query: 1   MLSGVWFLSVLTVAGILQTESRKTAKDICKIRCLCEEKENVLNINCENKGFTTVSLLQPP 60
           MLSGVWFLSVLTVAGILQTESRKTAKDICKIRCLCEEKENVLNINCENKGFTTVSLLQPP
Sbjct: 1   MLSGVWFLSVLTVAGILQTESRKTAKDICKIRCLCEEKENVLNINCENKGFTTVSLLQPP 60

Query: 61  QYRIYQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNN 120
           QYRIYQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNN
Sbjct: 61  QYRIYQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNN 120

Query: 121 KLEILREDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRF 180
           KLEILREDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRF
Sbjct: 121 KLEILREDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRF 180

Query: 181 VLLTHLDLRGNRLKVMPFAGVLEHIGGIMEIQLEENPWNCTCDLLPLKAWLDTITVFVGE 240
           VLLTHLDLRGNRLKVMPFAGVLEHIGGIMEIQLEENPWNCTCDLLPLKAWLDTITVFVGE
Sbjct: 181 VLLTHLDLRGNRLKVMPFAGVLEHIGGIMEIQLEENPWNCTCDLLPLKAWLDTITVFVGE 240

Query: 241 IVCETPFRLHGKDVTQLTRQDLCPRKSASDSSQRGSHADTHVQRLSPTMNPALNPTRAPK 300
           IVCETPFRLHGKDVTQLTRQDLCPRKSASDSSQRGSHADTHVQRLSPTMNPALNPTRAPK
Sbjct: 241 IVCETPFRLHGKDVTQLTRQDLCPRKSASDSSQRGSHADTHVQRLSPTMNPALNPTRAPK 300

Query: 301 ASRPPKMRNRPTPRVTVSKDRQSFGPIMVYQTKSPVPLTCPSSCVCTSQSSDNGLNVNCQ 360
           ASRPPKMRNRPTPRVTVSKDRQSFGPIMVYQTKSPVPLTCPSSCVCTSQSSDNGLNVNCQ
Sbjct: 301 ASRPPKMRNRPTPRVTVSKDRQSFGPIMVYQTKSPVPLTCPSSCVCTSQSSDNGLNVNCQ 360

Query: 361 ERKFTNISDLQPKPTSPKKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFT 420
           ERKFTNISDLQPKPTSPKKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFT
Sbjct: 361 ERKFTNISDLQPKPTSPKKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFT 420

Query: 421 NLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNN 480
           NLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNN
Sbjct: 421 NLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNN 480

Query: 481 NLLRSLPDNIFGGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMGL 540
           NLLRSLPDNIFGGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMGL
Sbjct: 481 NLLRSLPDNIFGGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMGL 540

Query: 541 KDWTEHANSPVIINEVTCESPAKHAGEILKFLGREAICPDSPNLSDGTVLSMNHNTDTPR 600
           KDWTEHANSPVIINEVTCESPAKHAGEILKFLGREAICPDSPNLSDGTVLSMNHNTDTPR
Sbjct: 541 KDWTEHANSPVIINEVTCESPAKHAGEILKFLGREAICPDSPNLSDGTVLSMNHNTDTPR 600

Query: 601 SLSVSPSSYPELHTEVPLSVLILGLLVVFILSVCFGAGLFVFVLKRRKGVPSVPRNTNNL 660
           SLSVSPSSYPELHTEVPLSVLILGLLVVFILSVCFGAGLFVFVLKRRKGVPSVPRNTNNL
Sbjct: 601 SLSVSPSSYPELHTEVPLSVLILGLLVVFILSVCFGAGLFVFVLKRRKGVPSVPRNTNNL 660

Query: 661 DVSSFQLQYGSYNTETHDKTDGHVYNYIPPPVGQMCQNPIYMQKEGDPVAYYRNLQEFSY 720
           DVSSFQLQYGSYNTETHDKTDGHVYNYIPPPVGQMCQNPIYMQKEGDPVAYYRNLQEFSY
Sbjct: 661 DVSSFQLQYGSYNTETHDKTDGHVYNYIPPPVGQMCQNPIYMQKEGDPVAYYRNLQEFSY 720

Query: 721 SNLEEKKEEPATPAYTISATELLEKQATPREPELLYQNIAERVKELPSAGLVHYNFCTLP 780
           SNLEEKKEEPATPAYTISATELLEKQATPREPELLYQNIAERVKELPSAGLVHYNFCTLP
Sbjct: 721 SNLEEKKEEPATPAYTISATELLEKQATPREPELLYQNIAERVKELPSAGLVHYNFCTLP 780

Query: 781 KRQFAPSYESRRQNQDRINKTVLYGTPRKCFVGQSKPNHPLLQAKPQSEPDYLEVLEKQT 840
           KRQFAPSYESRRQNQDRINKTVLYGTPRKCFVGQSKPNHPLLQAKPQSEPDYLEVLEKQT
Sbjct: 781 KRQFAPSYESRRQNQDRINKTVLYGTPRKCFVGQSKPNHPLLQAKPQSEPDYLEVLEKQT 840

Query: 841 AISQL 845
           AISQL
Sbjct: 841 AISQL 845


>gi|221136981 SLIT and NTRK-like family, member 2 [Homo sapiens]
          Length = 845

 Score = 1712 bits (4435), Expect = 0.0
 Identities = 845/845 (100%), Positives = 845/845 (100%)

Query: 1   MLSGVWFLSVLTVAGILQTESRKTAKDICKIRCLCEEKENVLNINCENKGFTTVSLLQPP 60
           MLSGVWFLSVLTVAGILQTESRKTAKDICKIRCLCEEKENVLNINCENKGFTTVSLLQPP
Sbjct: 1   MLSGVWFLSVLTVAGILQTESRKTAKDICKIRCLCEEKENVLNINCENKGFTTVSLLQPP 60

Query: 61  QYRIYQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNN 120
           QYRIYQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNN
Sbjct: 61  QYRIYQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNN 120

Query: 121 KLEILREDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRF 180
           KLEILREDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRF
Sbjct: 121 KLEILREDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRF 180

Query: 181 VLLTHLDLRGNRLKVMPFAGVLEHIGGIMEIQLEENPWNCTCDLLPLKAWLDTITVFVGE 240
           VLLTHLDLRGNRLKVMPFAGVLEHIGGIMEIQLEENPWNCTCDLLPLKAWLDTITVFVGE
Sbjct: 181 VLLTHLDLRGNRLKVMPFAGVLEHIGGIMEIQLEENPWNCTCDLLPLKAWLDTITVFVGE 240

Query: 241 IVCETPFRLHGKDVTQLTRQDLCPRKSASDSSQRGSHADTHVQRLSPTMNPALNPTRAPK 300
           IVCETPFRLHGKDVTQLTRQDLCPRKSASDSSQRGSHADTHVQRLSPTMNPALNPTRAPK
Sbjct: 241 IVCETPFRLHGKDVTQLTRQDLCPRKSASDSSQRGSHADTHVQRLSPTMNPALNPTRAPK 300

Query: 301 ASRPPKMRNRPTPRVTVSKDRQSFGPIMVYQTKSPVPLTCPSSCVCTSQSSDNGLNVNCQ 360
           ASRPPKMRNRPTPRVTVSKDRQSFGPIMVYQTKSPVPLTCPSSCVCTSQSSDNGLNVNCQ
Sbjct: 301 ASRPPKMRNRPTPRVTVSKDRQSFGPIMVYQTKSPVPLTCPSSCVCTSQSSDNGLNVNCQ 360

Query: 361 ERKFTNISDLQPKPTSPKKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFT 420
           ERKFTNISDLQPKPTSPKKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFT
Sbjct: 361 ERKFTNISDLQPKPTSPKKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFT 420

Query: 421 NLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNN 480
           NLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNN
Sbjct: 421 NLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNN 480

Query: 481 NLLRSLPDNIFGGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMGL 540
           NLLRSLPDNIFGGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMGL
Sbjct: 481 NLLRSLPDNIFGGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMGL 540

Query: 541 KDWTEHANSPVIINEVTCESPAKHAGEILKFLGREAICPDSPNLSDGTVLSMNHNTDTPR 600
           KDWTEHANSPVIINEVTCESPAKHAGEILKFLGREAICPDSPNLSDGTVLSMNHNTDTPR
Sbjct: 541 KDWTEHANSPVIINEVTCESPAKHAGEILKFLGREAICPDSPNLSDGTVLSMNHNTDTPR 600

Query: 601 SLSVSPSSYPELHTEVPLSVLILGLLVVFILSVCFGAGLFVFVLKRRKGVPSVPRNTNNL 660
           SLSVSPSSYPELHTEVPLSVLILGLLVVFILSVCFGAGLFVFVLKRRKGVPSVPRNTNNL
Sbjct: 601 SLSVSPSSYPELHTEVPLSVLILGLLVVFILSVCFGAGLFVFVLKRRKGVPSVPRNTNNL 660

Query: 661 DVSSFQLQYGSYNTETHDKTDGHVYNYIPPPVGQMCQNPIYMQKEGDPVAYYRNLQEFSY 720
           DVSSFQLQYGSYNTETHDKTDGHVYNYIPPPVGQMCQNPIYMQKEGDPVAYYRNLQEFSY
Sbjct: 661 DVSSFQLQYGSYNTETHDKTDGHVYNYIPPPVGQMCQNPIYMQKEGDPVAYYRNLQEFSY 720

Query: 721 SNLEEKKEEPATPAYTISATELLEKQATPREPELLYQNIAERVKELPSAGLVHYNFCTLP 780
           SNLEEKKEEPATPAYTISATELLEKQATPREPELLYQNIAERVKELPSAGLVHYNFCTLP
Sbjct: 721 SNLEEKKEEPATPAYTISATELLEKQATPREPELLYQNIAERVKELPSAGLVHYNFCTLP 780

Query: 781 KRQFAPSYESRRQNQDRINKTVLYGTPRKCFVGQSKPNHPLLQAKPQSEPDYLEVLEKQT 840
           KRQFAPSYESRRQNQDRINKTVLYGTPRKCFVGQSKPNHPLLQAKPQSEPDYLEVLEKQT
Sbjct: 781 KRQFAPSYESRRQNQDRINKTVLYGTPRKCFVGQSKPNHPLLQAKPQSEPDYLEVLEKQT 840

Query: 841 AISQL 845
           AISQL
Sbjct: 841 AISQL 845


>gi|221136977 SLIT and NTRK-like family, member 2 [Homo sapiens]
          Length = 845

 Score = 1712 bits (4435), Expect = 0.0
 Identities = 845/845 (100%), Positives = 845/845 (100%)

Query: 1   MLSGVWFLSVLTVAGILQTESRKTAKDICKIRCLCEEKENVLNINCENKGFTTVSLLQPP 60
           MLSGVWFLSVLTVAGILQTESRKTAKDICKIRCLCEEKENVLNINCENKGFTTVSLLQPP
Sbjct: 1   MLSGVWFLSVLTVAGILQTESRKTAKDICKIRCLCEEKENVLNINCENKGFTTVSLLQPP 60

Query: 61  QYRIYQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNN 120
           QYRIYQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNN
Sbjct: 61  QYRIYQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNN 120

Query: 121 KLEILREDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRF 180
           KLEILREDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRF
Sbjct: 121 KLEILREDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRF 180

Query: 181 VLLTHLDLRGNRLKVMPFAGVLEHIGGIMEIQLEENPWNCTCDLLPLKAWLDTITVFVGE 240
           VLLTHLDLRGNRLKVMPFAGVLEHIGGIMEIQLEENPWNCTCDLLPLKAWLDTITVFVGE
Sbjct: 181 VLLTHLDLRGNRLKVMPFAGVLEHIGGIMEIQLEENPWNCTCDLLPLKAWLDTITVFVGE 240

Query: 241 IVCETPFRLHGKDVTQLTRQDLCPRKSASDSSQRGSHADTHVQRLSPTMNPALNPTRAPK 300
           IVCETPFRLHGKDVTQLTRQDLCPRKSASDSSQRGSHADTHVQRLSPTMNPALNPTRAPK
Sbjct: 241 IVCETPFRLHGKDVTQLTRQDLCPRKSASDSSQRGSHADTHVQRLSPTMNPALNPTRAPK 300

Query: 301 ASRPPKMRNRPTPRVTVSKDRQSFGPIMVYQTKSPVPLTCPSSCVCTSQSSDNGLNVNCQ 360
           ASRPPKMRNRPTPRVTVSKDRQSFGPIMVYQTKSPVPLTCPSSCVCTSQSSDNGLNVNCQ
Sbjct: 301 ASRPPKMRNRPTPRVTVSKDRQSFGPIMVYQTKSPVPLTCPSSCVCTSQSSDNGLNVNCQ 360

Query: 361 ERKFTNISDLQPKPTSPKKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFT 420
           ERKFTNISDLQPKPTSPKKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFT
Sbjct: 361 ERKFTNISDLQPKPTSPKKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFT 420

Query: 421 NLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNN 480
           NLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNN
Sbjct: 421 NLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNN 480

Query: 481 NLLRSLPDNIFGGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMGL 540
           NLLRSLPDNIFGGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMGL
Sbjct: 481 NLLRSLPDNIFGGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMGL 540

Query: 541 KDWTEHANSPVIINEVTCESPAKHAGEILKFLGREAICPDSPNLSDGTVLSMNHNTDTPR 600
           KDWTEHANSPVIINEVTCESPAKHAGEILKFLGREAICPDSPNLSDGTVLSMNHNTDTPR
Sbjct: 541 KDWTEHANSPVIINEVTCESPAKHAGEILKFLGREAICPDSPNLSDGTVLSMNHNTDTPR 600

Query: 601 SLSVSPSSYPELHTEVPLSVLILGLLVVFILSVCFGAGLFVFVLKRRKGVPSVPRNTNNL 660
           SLSVSPSSYPELHTEVPLSVLILGLLVVFILSVCFGAGLFVFVLKRRKGVPSVPRNTNNL
Sbjct: 601 SLSVSPSSYPELHTEVPLSVLILGLLVVFILSVCFGAGLFVFVLKRRKGVPSVPRNTNNL 660

Query: 661 DVSSFQLQYGSYNTETHDKTDGHVYNYIPPPVGQMCQNPIYMQKEGDPVAYYRNLQEFSY 720
           DVSSFQLQYGSYNTETHDKTDGHVYNYIPPPVGQMCQNPIYMQKEGDPVAYYRNLQEFSY
Sbjct: 661 DVSSFQLQYGSYNTETHDKTDGHVYNYIPPPVGQMCQNPIYMQKEGDPVAYYRNLQEFSY 720

Query: 721 SNLEEKKEEPATPAYTISATELLEKQATPREPELLYQNIAERVKELPSAGLVHYNFCTLP 780
           SNLEEKKEEPATPAYTISATELLEKQATPREPELLYQNIAERVKELPSAGLVHYNFCTLP
Sbjct: 721 SNLEEKKEEPATPAYTISATELLEKQATPREPELLYQNIAERVKELPSAGLVHYNFCTLP 780

Query: 781 KRQFAPSYESRRQNQDRINKTVLYGTPRKCFVGQSKPNHPLLQAKPQSEPDYLEVLEKQT 840
           KRQFAPSYESRRQNQDRINKTVLYGTPRKCFVGQSKPNHPLLQAKPQSEPDYLEVLEKQT
Sbjct: 781 KRQFAPSYESRRQNQDRINKTVLYGTPRKCFVGQSKPNHPLLQAKPQSEPDYLEVLEKQT 840

Query: 841 AISQL 845
           AISQL
Sbjct: 841 AISQL 845


>gi|221136973 SLIT and NTRK-like family, member 2 [Homo sapiens]
          Length = 845

 Score = 1712 bits (4435), Expect = 0.0
 Identities = 845/845 (100%), Positives = 845/845 (100%)

Query: 1   MLSGVWFLSVLTVAGILQTESRKTAKDICKIRCLCEEKENVLNINCENKGFTTVSLLQPP 60
           MLSGVWFLSVLTVAGILQTESRKTAKDICKIRCLCEEKENVLNINCENKGFTTVSLLQPP
Sbjct: 1   MLSGVWFLSVLTVAGILQTESRKTAKDICKIRCLCEEKENVLNINCENKGFTTVSLLQPP 60

Query: 61  QYRIYQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNN 120
           QYRIYQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNN
Sbjct: 61  QYRIYQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNN 120

Query: 121 KLEILREDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRF 180
           KLEILREDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRF
Sbjct: 121 KLEILREDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRF 180

Query: 181 VLLTHLDLRGNRLKVMPFAGVLEHIGGIMEIQLEENPWNCTCDLLPLKAWLDTITVFVGE 240
           VLLTHLDLRGNRLKVMPFAGVLEHIGGIMEIQLEENPWNCTCDLLPLKAWLDTITVFVGE
Sbjct: 181 VLLTHLDLRGNRLKVMPFAGVLEHIGGIMEIQLEENPWNCTCDLLPLKAWLDTITVFVGE 240

Query: 241 IVCETPFRLHGKDVTQLTRQDLCPRKSASDSSQRGSHADTHVQRLSPTMNPALNPTRAPK 300
           IVCETPFRLHGKDVTQLTRQDLCPRKSASDSSQRGSHADTHVQRLSPTMNPALNPTRAPK
Sbjct: 241 IVCETPFRLHGKDVTQLTRQDLCPRKSASDSSQRGSHADTHVQRLSPTMNPALNPTRAPK 300

Query: 301 ASRPPKMRNRPTPRVTVSKDRQSFGPIMVYQTKSPVPLTCPSSCVCTSQSSDNGLNVNCQ 360
           ASRPPKMRNRPTPRVTVSKDRQSFGPIMVYQTKSPVPLTCPSSCVCTSQSSDNGLNVNCQ
Sbjct: 301 ASRPPKMRNRPTPRVTVSKDRQSFGPIMVYQTKSPVPLTCPSSCVCTSQSSDNGLNVNCQ 360

Query: 361 ERKFTNISDLQPKPTSPKKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFT 420
           ERKFTNISDLQPKPTSPKKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFT
Sbjct: 361 ERKFTNISDLQPKPTSPKKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFT 420

Query: 421 NLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNN 480
           NLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNN
Sbjct: 421 NLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNN 480

Query: 481 NLLRSLPDNIFGGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMGL 540
           NLLRSLPDNIFGGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMGL
Sbjct: 481 NLLRSLPDNIFGGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMGL 540

Query: 541 KDWTEHANSPVIINEVTCESPAKHAGEILKFLGREAICPDSPNLSDGTVLSMNHNTDTPR 600
           KDWTEHANSPVIINEVTCESPAKHAGEILKFLGREAICPDSPNLSDGTVLSMNHNTDTPR
Sbjct: 541 KDWTEHANSPVIINEVTCESPAKHAGEILKFLGREAICPDSPNLSDGTVLSMNHNTDTPR 600

Query: 601 SLSVSPSSYPELHTEVPLSVLILGLLVVFILSVCFGAGLFVFVLKRRKGVPSVPRNTNNL 660
           SLSVSPSSYPELHTEVPLSVLILGLLVVFILSVCFGAGLFVFVLKRRKGVPSVPRNTNNL
Sbjct: 601 SLSVSPSSYPELHTEVPLSVLILGLLVVFILSVCFGAGLFVFVLKRRKGVPSVPRNTNNL 660

Query: 661 DVSSFQLQYGSYNTETHDKTDGHVYNYIPPPVGQMCQNPIYMQKEGDPVAYYRNLQEFSY 720
           DVSSFQLQYGSYNTETHDKTDGHVYNYIPPPVGQMCQNPIYMQKEGDPVAYYRNLQEFSY
Sbjct: 661 DVSSFQLQYGSYNTETHDKTDGHVYNYIPPPVGQMCQNPIYMQKEGDPVAYYRNLQEFSY 720

Query: 721 SNLEEKKEEPATPAYTISATELLEKQATPREPELLYQNIAERVKELPSAGLVHYNFCTLP 780
           SNLEEKKEEPATPAYTISATELLEKQATPREPELLYQNIAERVKELPSAGLVHYNFCTLP
Sbjct: 721 SNLEEKKEEPATPAYTISATELLEKQATPREPELLYQNIAERVKELPSAGLVHYNFCTLP 780

Query: 781 KRQFAPSYESRRQNQDRINKTVLYGTPRKCFVGQSKPNHPLLQAKPQSEPDYLEVLEKQT 840
           KRQFAPSYESRRQNQDRINKTVLYGTPRKCFVGQSKPNHPLLQAKPQSEPDYLEVLEKQT
Sbjct: 781 KRQFAPSYESRRQNQDRINKTVLYGTPRKCFVGQSKPNHPLLQAKPQSEPDYLEVLEKQT 840

Query: 841 AISQL 845
           AISQL
Sbjct: 841 AISQL 845


>gi|221136969 SLIT and NTRK-like family, member 2 [Homo sapiens]
          Length = 845

 Score = 1712 bits (4435), Expect = 0.0
 Identities = 845/845 (100%), Positives = 845/845 (100%)

Query: 1   MLSGVWFLSVLTVAGILQTESRKTAKDICKIRCLCEEKENVLNINCENKGFTTVSLLQPP 60
           MLSGVWFLSVLTVAGILQTESRKTAKDICKIRCLCEEKENVLNINCENKGFTTVSLLQPP
Sbjct: 1   MLSGVWFLSVLTVAGILQTESRKTAKDICKIRCLCEEKENVLNINCENKGFTTVSLLQPP 60

Query: 61  QYRIYQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNN 120
           QYRIYQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNN
Sbjct: 61  QYRIYQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNN 120

Query: 121 KLEILREDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRF 180
           KLEILREDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRF
Sbjct: 121 KLEILREDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRF 180

Query: 181 VLLTHLDLRGNRLKVMPFAGVLEHIGGIMEIQLEENPWNCTCDLLPLKAWLDTITVFVGE 240
           VLLTHLDLRGNRLKVMPFAGVLEHIGGIMEIQLEENPWNCTCDLLPLKAWLDTITVFVGE
Sbjct: 181 VLLTHLDLRGNRLKVMPFAGVLEHIGGIMEIQLEENPWNCTCDLLPLKAWLDTITVFVGE 240

Query: 241 IVCETPFRLHGKDVTQLTRQDLCPRKSASDSSQRGSHADTHVQRLSPTMNPALNPTRAPK 300
           IVCETPFRLHGKDVTQLTRQDLCPRKSASDSSQRGSHADTHVQRLSPTMNPALNPTRAPK
Sbjct: 241 IVCETPFRLHGKDVTQLTRQDLCPRKSASDSSQRGSHADTHVQRLSPTMNPALNPTRAPK 300

Query: 301 ASRPPKMRNRPTPRVTVSKDRQSFGPIMVYQTKSPVPLTCPSSCVCTSQSSDNGLNVNCQ 360
           ASRPPKMRNRPTPRVTVSKDRQSFGPIMVYQTKSPVPLTCPSSCVCTSQSSDNGLNVNCQ
Sbjct: 301 ASRPPKMRNRPTPRVTVSKDRQSFGPIMVYQTKSPVPLTCPSSCVCTSQSSDNGLNVNCQ 360

Query: 361 ERKFTNISDLQPKPTSPKKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFT 420
           ERKFTNISDLQPKPTSPKKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFT
Sbjct: 361 ERKFTNISDLQPKPTSPKKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFT 420

Query: 421 NLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNN 480
           NLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNN
Sbjct: 421 NLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNN 480

Query: 481 NLLRSLPDNIFGGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMGL 540
           NLLRSLPDNIFGGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMGL
Sbjct: 481 NLLRSLPDNIFGGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMGL 540

Query: 541 KDWTEHANSPVIINEVTCESPAKHAGEILKFLGREAICPDSPNLSDGTVLSMNHNTDTPR 600
           KDWTEHANSPVIINEVTCESPAKHAGEILKFLGREAICPDSPNLSDGTVLSMNHNTDTPR
Sbjct: 541 KDWTEHANSPVIINEVTCESPAKHAGEILKFLGREAICPDSPNLSDGTVLSMNHNTDTPR 600

Query: 601 SLSVSPSSYPELHTEVPLSVLILGLLVVFILSVCFGAGLFVFVLKRRKGVPSVPRNTNNL 660
           SLSVSPSSYPELHTEVPLSVLILGLLVVFILSVCFGAGLFVFVLKRRKGVPSVPRNTNNL
Sbjct: 601 SLSVSPSSYPELHTEVPLSVLILGLLVVFILSVCFGAGLFVFVLKRRKGVPSVPRNTNNL 660

Query: 661 DVSSFQLQYGSYNTETHDKTDGHVYNYIPPPVGQMCQNPIYMQKEGDPVAYYRNLQEFSY 720
           DVSSFQLQYGSYNTETHDKTDGHVYNYIPPPVGQMCQNPIYMQKEGDPVAYYRNLQEFSY
Sbjct: 661 DVSSFQLQYGSYNTETHDKTDGHVYNYIPPPVGQMCQNPIYMQKEGDPVAYYRNLQEFSY 720

Query: 721 SNLEEKKEEPATPAYTISATELLEKQATPREPELLYQNIAERVKELPSAGLVHYNFCTLP 780
           SNLEEKKEEPATPAYTISATELLEKQATPREPELLYQNIAERVKELPSAGLVHYNFCTLP
Sbjct: 721 SNLEEKKEEPATPAYTISATELLEKQATPREPELLYQNIAERVKELPSAGLVHYNFCTLP 780

Query: 781 KRQFAPSYESRRQNQDRINKTVLYGTPRKCFVGQSKPNHPLLQAKPQSEPDYLEVLEKQT 840
           KRQFAPSYESRRQNQDRINKTVLYGTPRKCFVGQSKPNHPLLQAKPQSEPDYLEVLEKQT
Sbjct: 781 KRQFAPSYESRRQNQDRINKTVLYGTPRKCFVGQSKPNHPLLQAKPQSEPDYLEVLEKQT 840

Query: 841 AISQL 845
           AISQL
Sbjct: 841 AISQL 845


>gi|221136965 SLIT and NTRK-like family, member 2 [Homo sapiens]
          Length = 845

 Score = 1712 bits (4435), Expect = 0.0
 Identities = 845/845 (100%), Positives = 845/845 (100%)

Query: 1   MLSGVWFLSVLTVAGILQTESRKTAKDICKIRCLCEEKENVLNINCENKGFTTVSLLQPP 60
           MLSGVWFLSVLTVAGILQTESRKTAKDICKIRCLCEEKENVLNINCENKGFTTVSLLQPP
Sbjct: 1   MLSGVWFLSVLTVAGILQTESRKTAKDICKIRCLCEEKENVLNINCENKGFTTVSLLQPP 60

Query: 61  QYRIYQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNN 120
           QYRIYQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNN
Sbjct: 61  QYRIYQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNN 120

Query: 121 KLEILREDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRF 180
           KLEILREDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRF
Sbjct: 121 KLEILREDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRF 180

Query: 181 VLLTHLDLRGNRLKVMPFAGVLEHIGGIMEIQLEENPWNCTCDLLPLKAWLDTITVFVGE 240
           VLLTHLDLRGNRLKVMPFAGVLEHIGGIMEIQLEENPWNCTCDLLPLKAWLDTITVFVGE
Sbjct: 181 VLLTHLDLRGNRLKVMPFAGVLEHIGGIMEIQLEENPWNCTCDLLPLKAWLDTITVFVGE 240

Query: 241 IVCETPFRLHGKDVTQLTRQDLCPRKSASDSSQRGSHADTHVQRLSPTMNPALNPTRAPK 300
           IVCETPFRLHGKDVTQLTRQDLCPRKSASDSSQRGSHADTHVQRLSPTMNPALNPTRAPK
Sbjct: 241 IVCETPFRLHGKDVTQLTRQDLCPRKSASDSSQRGSHADTHVQRLSPTMNPALNPTRAPK 300

Query: 301 ASRPPKMRNRPTPRVTVSKDRQSFGPIMVYQTKSPVPLTCPSSCVCTSQSSDNGLNVNCQ 360
           ASRPPKMRNRPTPRVTVSKDRQSFGPIMVYQTKSPVPLTCPSSCVCTSQSSDNGLNVNCQ
Sbjct: 301 ASRPPKMRNRPTPRVTVSKDRQSFGPIMVYQTKSPVPLTCPSSCVCTSQSSDNGLNVNCQ 360

Query: 361 ERKFTNISDLQPKPTSPKKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFT 420
           ERKFTNISDLQPKPTSPKKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFT
Sbjct: 361 ERKFTNISDLQPKPTSPKKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFT 420

Query: 421 NLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNN 480
           NLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNN
Sbjct: 421 NLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNN 480

Query: 481 NLLRSLPDNIFGGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMGL 540
           NLLRSLPDNIFGGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMGL
Sbjct: 481 NLLRSLPDNIFGGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMGL 540

Query: 541 KDWTEHANSPVIINEVTCESPAKHAGEILKFLGREAICPDSPNLSDGTVLSMNHNTDTPR 600
           KDWTEHANSPVIINEVTCESPAKHAGEILKFLGREAICPDSPNLSDGTVLSMNHNTDTPR
Sbjct: 541 KDWTEHANSPVIINEVTCESPAKHAGEILKFLGREAICPDSPNLSDGTVLSMNHNTDTPR 600

Query: 601 SLSVSPSSYPELHTEVPLSVLILGLLVVFILSVCFGAGLFVFVLKRRKGVPSVPRNTNNL 660
           SLSVSPSSYPELHTEVPLSVLILGLLVVFILSVCFGAGLFVFVLKRRKGVPSVPRNTNNL
Sbjct: 601 SLSVSPSSYPELHTEVPLSVLILGLLVVFILSVCFGAGLFVFVLKRRKGVPSVPRNTNNL 660

Query: 661 DVSSFQLQYGSYNTETHDKTDGHVYNYIPPPVGQMCQNPIYMQKEGDPVAYYRNLQEFSY 720
           DVSSFQLQYGSYNTETHDKTDGHVYNYIPPPVGQMCQNPIYMQKEGDPVAYYRNLQEFSY
Sbjct: 661 DVSSFQLQYGSYNTETHDKTDGHVYNYIPPPVGQMCQNPIYMQKEGDPVAYYRNLQEFSY 720

Query: 721 SNLEEKKEEPATPAYTISATELLEKQATPREPELLYQNIAERVKELPSAGLVHYNFCTLP 780
           SNLEEKKEEPATPAYTISATELLEKQATPREPELLYQNIAERVKELPSAGLVHYNFCTLP
Sbjct: 721 SNLEEKKEEPATPAYTISATELLEKQATPREPELLYQNIAERVKELPSAGLVHYNFCTLP 780

Query: 781 KRQFAPSYESRRQNQDRINKTVLYGTPRKCFVGQSKPNHPLLQAKPQSEPDYLEVLEKQT 840
           KRQFAPSYESRRQNQDRINKTVLYGTPRKCFVGQSKPNHPLLQAKPQSEPDYLEVLEKQT
Sbjct: 781 KRQFAPSYESRRQNQDRINKTVLYGTPRKCFVGQSKPNHPLLQAKPQSEPDYLEVLEKQT 840

Query: 841 AISQL 845
           AISQL
Sbjct: 841 AISQL 845


>gi|221136961 SLIT and NTRK-like family, member 2 [Homo sapiens]
          Length = 845

 Score = 1712 bits (4435), Expect = 0.0
 Identities = 845/845 (100%), Positives = 845/845 (100%)

Query: 1   MLSGVWFLSVLTVAGILQTESRKTAKDICKIRCLCEEKENVLNINCENKGFTTVSLLQPP 60
           MLSGVWFLSVLTVAGILQTESRKTAKDICKIRCLCEEKENVLNINCENKGFTTVSLLQPP
Sbjct: 1   MLSGVWFLSVLTVAGILQTESRKTAKDICKIRCLCEEKENVLNINCENKGFTTVSLLQPP 60

Query: 61  QYRIYQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNN 120
           QYRIYQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNN
Sbjct: 61  QYRIYQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNN 120

Query: 121 KLEILREDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRF 180
           KLEILREDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRF
Sbjct: 121 KLEILREDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRF 180

Query: 181 VLLTHLDLRGNRLKVMPFAGVLEHIGGIMEIQLEENPWNCTCDLLPLKAWLDTITVFVGE 240
           VLLTHLDLRGNRLKVMPFAGVLEHIGGIMEIQLEENPWNCTCDLLPLKAWLDTITVFVGE
Sbjct: 181 VLLTHLDLRGNRLKVMPFAGVLEHIGGIMEIQLEENPWNCTCDLLPLKAWLDTITVFVGE 240

Query: 241 IVCETPFRLHGKDVTQLTRQDLCPRKSASDSSQRGSHADTHVQRLSPTMNPALNPTRAPK 300
           IVCETPFRLHGKDVTQLTRQDLCPRKSASDSSQRGSHADTHVQRLSPTMNPALNPTRAPK
Sbjct: 241 IVCETPFRLHGKDVTQLTRQDLCPRKSASDSSQRGSHADTHVQRLSPTMNPALNPTRAPK 300

Query: 301 ASRPPKMRNRPTPRVTVSKDRQSFGPIMVYQTKSPVPLTCPSSCVCTSQSSDNGLNVNCQ 360
           ASRPPKMRNRPTPRVTVSKDRQSFGPIMVYQTKSPVPLTCPSSCVCTSQSSDNGLNVNCQ
Sbjct: 301 ASRPPKMRNRPTPRVTVSKDRQSFGPIMVYQTKSPVPLTCPSSCVCTSQSSDNGLNVNCQ 360

Query: 361 ERKFTNISDLQPKPTSPKKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFT 420
           ERKFTNISDLQPKPTSPKKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFT
Sbjct: 361 ERKFTNISDLQPKPTSPKKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFT 420

Query: 421 NLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNN 480
           NLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNN
Sbjct: 421 NLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNN 480

Query: 481 NLLRSLPDNIFGGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMGL 540
           NLLRSLPDNIFGGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMGL
Sbjct: 481 NLLRSLPDNIFGGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMGL 540

Query: 541 KDWTEHANSPVIINEVTCESPAKHAGEILKFLGREAICPDSPNLSDGTVLSMNHNTDTPR 600
           KDWTEHANSPVIINEVTCESPAKHAGEILKFLGREAICPDSPNLSDGTVLSMNHNTDTPR
Sbjct: 541 KDWTEHANSPVIINEVTCESPAKHAGEILKFLGREAICPDSPNLSDGTVLSMNHNTDTPR 600

Query: 601 SLSVSPSSYPELHTEVPLSVLILGLLVVFILSVCFGAGLFVFVLKRRKGVPSVPRNTNNL 660
           SLSVSPSSYPELHTEVPLSVLILGLLVVFILSVCFGAGLFVFVLKRRKGVPSVPRNTNNL
Sbjct: 601 SLSVSPSSYPELHTEVPLSVLILGLLVVFILSVCFGAGLFVFVLKRRKGVPSVPRNTNNL 660

Query: 661 DVSSFQLQYGSYNTETHDKTDGHVYNYIPPPVGQMCQNPIYMQKEGDPVAYYRNLQEFSY 720
           DVSSFQLQYGSYNTETHDKTDGHVYNYIPPPVGQMCQNPIYMQKEGDPVAYYRNLQEFSY
Sbjct: 661 DVSSFQLQYGSYNTETHDKTDGHVYNYIPPPVGQMCQNPIYMQKEGDPVAYYRNLQEFSY 720

Query: 721 SNLEEKKEEPATPAYTISATELLEKQATPREPELLYQNIAERVKELPSAGLVHYNFCTLP 780
           SNLEEKKEEPATPAYTISATELLEKQATPREPELLYQNIAERVKELPSAGLVHYNFCTLP
Sbjct: 721 SNLEEKKEEPATPAYTISATELLEKQATPREPELLYQNIAERVKELPSAGLVHYNFCTLP 780

Query: 781 KRQFAPSYESRRQNQDRINKTVLYGTPRKCFVGQSKPNHPLLQAKPQSEPDYLEVLEKQT 840
           KRQFAPSYESRRQNQDRINKTVLYGTPRKCFVGQSKPNHPLLQAKPQSEPDYLEVLEKQT
Sbjct: 781 KRQFAPSYESRRQNQDRINKTVLYGTPRKCFVGQSKPNHPLLQAKPQSEPDYLEVLEKQT 840

Query: 841 AISQL 845
           AISQL
Sbjct: 841 AISQL 845


>gi|221136957 SLIT and NTRK-like family, member 2 [Homo sapiens]
          Length = 845

 Score = 1712 bits (4435), Expect = 0.0
 Identities = 845/845 (100%), Positives = 845/845 (100%)

Query: 1   MLSGVWFLSVLTVAGILQTESRKTAKDICKIRCLCEEKENVLNINCENKGFTTVSLLQPP 60
           MLSGVWFLSVLTVAGILQTESRKTAKDICKIRCLCEEKENVLNINCENKGFTTVSLLQPP
Sbjct: 1   MLSGVWFLSVLTVAGILQTESRKTAKDICKIRCLCEEKENVLNINCENKGFTTVSLLQPP 60

Query: 61  QYRIYQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNN 120
           QYRIYQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNN
Sbjct: 61  QYRIYQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNN 120

Query: 121 KLEILREDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRF 180
           KLEILREDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRF
Sbjct: 121 KLEILREDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRF 180

Query: 181 VLLTHLDLRGNRLKVMPFAGVLEHIGGIMEIQLEENPWNCTCDLLPLKAWLDTITVFVGE 240
           VLLTHLDLRGNRLKVMPFAGVLEHIGGIMEIQLEENPWNCTCDLLPLKAWLDTITVFVGE
Sbjct: 181 VLLTHLDLRGNRLKVMPFAGVLEHIGGIMEIQLEENPWNCTCDLLPLKAWLDTITVFVGE 240

Query: 241 IVCETPFRLHGKDVTQLTRQDLCPRKSASDSSQRGSHADTHVQRLSPTMNPALNPTRAPK 300
           IVCETPFRLHGKDVTQLTRQDLCPRKSASDSSQRGSHADTHVQRLSPTMNPALNPTRAPK
Sbjct: 241 IVCETPFRLHGKDVTQLTRQDLCPRKSASDSSQRGSHADTHVQRLSPTMNPALNPTRAPK 300

Query: 301 ASRPPKMRNRPTPRVTVSKDRQSFGPIMVYQTKSPVPLTCPSSCVCTSQSSDNGLNVNCQ 360
           ASRPPKMRNRPTPRVTVSKDRQSFGPIMVYQTKSPVPLTCPSSCVCTSQSSDNGLNVNCQ
Sbjct: 301 ASRPPKMRNRPTPRVTVSKDRQSFGPIMVYQTKSPVPLTCPSSCVCTSQSSDNGLNVNCQ 360

Query: 361 ERKFTNISDLQPKPTSPKKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFT 420
           ERKFTNISDLQPKPTSPKKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFT
Sbjct: 361 ERKFTNISDLQPKPTSPKKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFT 420

Query: 421 NLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNN 480
           NLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNN
Sbjct: 421 NLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNN 480

Query: 481 NLLRSLPDNIFGGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMGL 540
           NLLRSLPDNIFGGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMGL
Sbjct: 481 NLLRSLPDNIFGGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMGL 540

Query: 541 KDWTEHANSPVIINEVTCESPAKHAGEILKFLGREAICPDSPNLSDGTVLSMNHNTDTPR 600
           KDWTEHANSPVIINEVTCESPAKHAGEILKFLGREAICPDSPNLSDGTVLSMNHNTDTPR
Sbjct: 541 KDWTEHANSPVIINEVTCESPAKHAGEILKFLGREAICPDSPNLSDGTVLSMNHNTDTPR 600

Query: 601 SLSVSPSSYPELHTEVPLSVLILGLLVVFILSVCFGAGLFVFVLKRRKGVPSVPRNTNNL 660
           SLSVSPSSYPELHTEVPLSVLILGLLVVFILSVCFGAGLFVFVLKRRKGVPSVPRNTNNL
Sbjct: 601 SLSVSPSSYPELHTEVPLSVLILGLLVVFILSVCFGAGLFVFVLKRRKGVPSVPRNTNNL 660

Query: 661 DVSSFQLQYGSYNTETHDKTDGHVYNYIPPPVGQMCQNPIYMQKEGDPVAYYRNLQEFSY 720
           DVSSFQLQYGSYNTETHDKTDGHVYNYIPPPVGQMCQNPIYMQKEGDPVAYYRNLQEFSY
Sbjct: 661 DVSSFQLQYGSYNTETHDKTDGHVYNYIPPPVGQMCQNPIYMQKEGDPVAYYRNLQEFSY 720

Query: 721 SNLEEKKEEPATPAYTISATELLEKQATPREPELLYQNIAERVKELPSAGLVHYNFCTLP 780
           SNLEEKKEEPATPAYTISATELLEKQATPREPELLYQNIAERVKELPSAGLVHYNFCTLP
Sbjct: 721 SNLEEKKEEPATPAYTISATELLEKQATPREPELLYQNIAERVKELPSAGLVHYNFCTLP 780

Query: 781 KRQFAPSYESRRQNQDRINKTVLYGTPRKCFVGQSKPNHPLLQAKPQSEPDYLEVLEKQT 840
           KRQFAPSYESRRQNQDRINKTVLYGTPRKCFVGQSKPNHPLLQAKPQSEPDYLEVLEKQT
Sbjct: 781 KRQFAPSYESRRQNQDRINKTVLYGTPRKCFVGQSKPNHPLLQAKPQSEPDYLEVLEKQT 840

Query: 841 AISQL 845
           AISQL
Sbjct: 841 AISQL 845


>gi|33504581 SLIT and NTRK-like family, member 2 [Homo sapiens]
          Length = 845

 Score = 1712 bits (4435), Expect = 0.0
 Identities = 845/845 (100%), Positives = 845/845 (100%)

Query: 1   MLSGVWFLSVLTVAGILQTESRKTAKDICKIRCLCEEKENVLNINCENKGFTTVSLLQPP 60
           MLSGVWFLSVLTVAGILQTESRKTAKDICKIRCLCEEKENVLNINCENKGFTTVSLLQPP
Sbjct: 1   MLSGVWFLSVLTVAGILQTESRKTAKDICKIRCLCEEKENVLNINCENKGFTTVSLLQPP 60

Query: 61  QYRIYQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNN 120
           QYRIYQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNN
Sbjct: 61  QYRIYQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNN 120

Query: 121 KLEILREDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRF 180
           KLEILREDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRF
Sbjct: 121 KLEILREDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRF 180

Query: 181 VLLTHLDLRGNRLKVMPFAGVLEHIGGIMEIQLEENPWNCTCDLLPLKAWLDTITVFVGE 240
           VLLTHLDLRGNRLKVMPFAGVLEHIGGIMEIQLEENPWNCTCDLLPLKAWLDTITVFVGE
Sbjct: 181 VLLTHLDLRGNRLKVMPFAGVLEHIGGIMEIQLEENPWNCTCDLLPLKAWLDTITVFVGE 240

Query: 241 IVCETPFRLHGKDVTQLTRQDLCPRKSASDSSQRGSHADTHVQRLSPTMNPALNPTRAPK 300
           IVCETPFRLHGKDVTQLTRQDLCPRKSASDSSQRGSHADTHVQRLSPTMNPALNPTRAPK
Sbjct: 241 IVCETPFRLHGKDVTQLTRQDLCPRKSASDSSQRGSHADTHVQRLSPTMNPALNPTRAPK 300

Query: 301 ASRPPKMRNRPTPRVTVSKDRQSFGPIMVYQTKSPVPLTCPSSCVCTSQSSDNGLNVNCQ 360
           ASRPPKMRNRPTPRVTVSKDRQSFGPIMVYQTKSPVPLTCPSSCVCTSQSSDNGLNVNCQ
Sbjct: 301 ASRPPKMRNRPTPRVTVSKDRQSFGPIMVYQTKSPVPLTCPSSCVCTSQSSDNGLNVNCQ 360

Query: 361 ERKFTNISDLQPKPTSPKKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFT 420
           ERKFTNISDLQPKPTSPKKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFT
Sbjct: 361 ERKFTNISDLQPKPTSPKKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFT 420

Query: 421 NLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNN 480
           NLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNN
Sbjct: 421 NLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNN 480

Query: 481 NLLRSLPDNIFGGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMGL 540
           NLLRSLPDNIFGGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMGL
Sbjct: 481 NLLRSLPDNIFGGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMGL 540

Query: 541 KDWTEHANSPVIINEVTCESPAKHAGEILKFLGREAICPDSPNLSDGTVLSMNHNTDTPR 600
           KDWTEHANSPVIINEVTCESPAKHAGEILKFLGREAICPDSPNLSDGTVLSMNHNTDTPR
Sbjct: 541 KDWTEHANSPVIINEVTCESPAKHAGEILKFLGREAICPDSPNLSDGTVLSMNHNTDTPR 600

Query: 601 SLSVSPSSYPELHTEVPLSVLILGLLVVFILSVCFGAGLFVFVLKRRKGVPSVPRNTNNL 660
           SLSVSPSSYPELHTEVPLSVLILGLLVVFILSVCFGAGLFVFVLKRRKGVPSVPRNTNNL
Sbjct: 601 SLSVSPSSYPELHTEVPLSVLILGLLVVFILSVCFGAGLFVFVLKRRKGVPSVPRNTNNL 660

Query: 661 DVSSFQLQYGSYNTETHDKTDGHVYNYIPPPVGQMCQNPIYMQKEGDPVAYYRNLQEFSY 720
           DVSSFQLQYGSYNTETHDKTDGHVYNYIPPPVGQMCQNPIYMQKEGDPVAYYRNLQEFSY
Sbjct: 661 DVSSFQLQYGSYNTETHDKTDGHVYNYIPPPVGQMCQNPIYMQKEGDPVAYYRNLQEFSY 720

Query: 721 SNLEEKKEEPATPAYTISATELLEKQATPREPELLYQNIAERVKELPSAGLVHYNFCTLP 780
           SNLEEKKEEPATPAYTISATELLEKQATPREPELLYQNIAERVKELPSAGLVHYNFCTLP
Sbjct: 721 SNLEEKKEEPATPAYTISATELLEKQATPREPELLYQNIAERVKELPSAGLVHYNFCTLP 780

Query: 781 KRQFAPSYESRRQNQDRINKTVLYGTPRKCFVGQSKPNHPLLQAKPQSEPDYLEVLEKQT 840
           KRQFAPSYESRRQNQDRINKTVLYGTPRKCFVGQSKPNHPLLQAKPQSEPDYLEVLEKQT
Sbjct: 781 KRQFAPSYESRRQNQDRINKTVLYGTPRKCFVGQSKPNHPLLQAKPQSEPDYLEVLEKQT 840

Query: 841 AISQL 845
           AISQL
Sbjct: 841 AISQL 845


>gi|40217823 SLIT and NTRK-like family, member 5 [Homo sapiens]
          Length = 958

 Score =  799 bits (2063), Expect = 0.0
 Identities = 440/918 (47%), Positives = 584/918 (63%), Gaps = 106/918 (11%)

Query: 27  DICKIRCLCEEKENVLNINCENKGFTTVSLLQPPQYRIYQLFLNGNLLTRLYPNEFVNYS 86
           +IC   C CEEK+ +L ++CEN+G  ++S + PP++ IY L L+GNLL RLYPNEFVNY+
Sbjct: 46  EICDNACPCEEKDGILTVSCENRGIISLSEISPPRFPIYHLLLSGNLLNRLYPNEFVNYT 105

Query: 87  NAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLEILREDTFLGLESLEYLQADYNYI 146
            A  LHLG+N +Q+I TGAF GL+ L+RLHLNNNKLE+LR+DTFLGLE+LEYLQ DYNYI
Sbjct: 106 GASILHLGSNVIQDIETGAFHGLRGLRRLHLNNNKLELLRDDTFLGLENLEYLQVDYNYI 165

Query: 147 SAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRFVLLTHLDLRGNRLKVMPFAGVLEHIG 206
           S IE  AF KL+ L+VLILNDNLL SLP+N+FRFV LTHLDLRGNRLK++P+ G+L+H+ 
Sbjct: 166 SVIEPNAFGKLHLLQVLILNDNLLSSLPNNLFRFVPLTHLDLRGNRLKLLPYVGLLQHMD 225

Query: 207 GIMEIQLEENPWNCTCDLLPLKAWLDTIT--VFVGEIVCETPFRLHGKDVTQLTRQDLCP 264
            ++E+QLEENPWNC+C+L+ LK WLD+I+    VG++VCETPFRLHG+D+ ++++Q+LCP
Sbjct: 226 KVVELQLEENPWNCSCELISLKDWLDSISYSALVGDVVCETPFRLHGRDLDEVSKQELCP 285

Query: 265 RKSASDSSQRGS---------HADTHVQRLSPTMNPALN--PTRAPKASRPP-KMRNRPT 312
           R+  SD   R           H          T + A+   P + PK +R P K R RPT
Sbjct: 286 RRLISDYEMRPQTPLSTTGYLHTTPASVNSVATSSSAVYKPPLKPPKGTRQPNKPRVRPT 345

Query: 313 PRVTVSKDR--QSFGPIMVYQTKSPVPLTCPSSCVCTSQSSDNGLNVNCQERKFTNISDL 370
            R   SKD    ++GP + YQTKSPVPL CP++C C  Q SD GLNVNCQERK  +I++L
Sbjct: 346 SRQP-SKDLGYSNYGPSIAYQTKSPVPLECPTACSCNLQISDLGLNVNCQERKIESIAEL 404

Query: 371 QPKPTSPKKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFTNLTSLRRLYL 430
           QPKP +PKK+YLT NY+  V + D LE + LDLLHLGNNRI++IQ+ AF +LT+LRRLYL
Sbjct: 405 QPKPYNPKKMYLTENYIAVVRRTDFLEATGLDLLHLGNNRISMIQDRAFGDLTNLRRLYL 464

Query: 431 NGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNNNLLRSLPDNI 490
           NGN +E L P +F GLQSLQYL+L+YN+I+EI+  TFD + NLQLLFLNNNLL+++P  +
Sbjct: 465 NGNRIERLSPELFYGLQSLQYLFLQYNLIREIQSGTFDPVPNLQLLFLNNNLLQAMPSGV 524

Query: 491 FGGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMGLKDWTEHANSP 550
           F G  L RLNLR+NHF+ LPV GVLDQL + IQIDL +NPWDCTCDI+G+K W E     
Sbjct: 525 FSGLTLLRLNLRSNHFTSLPVSGVLDQLKSLIQIDLHDNPWDCTCDIVGMKLWVEQLKVG 584

Query: 551 VIINEVTCESPAKHAGEILKFLGREAICPDSPNLSDGTVLSMN----------------H 594
           V+++EV C++P K A   ++ +  E +CPD  ++   T    +                +
Sbjct: 585 VLVDEVICKAPKKFAETDMRSIKSELLCPDYSDVVVSTPTPSSIQVPARTSAVTPAVRLN 644

Query: 595 NTDTPRSLSVSPSSYPELHTEVPLSVLILGLLVVFILSVCFGAGLFVFVLKRRKGVPSVP 654
           +T  P SL     +     + VPLSVLIL LL+VFI+SV   AGLFV V+KRRK   S  
Sbjct: 645 STGAPASLGAGGGA-----SSVPLSVLILSLLLVFIMSVFVAAGLFVLVMKRRKKNQSDH 699

Query: 655 RNTNNLDVSSFQLQYGSY----------NTETHDK---------TDGHVYNYIPPPVGQM 695
            +TNN DVSSF +QY  Y          +   H +           GHVY YIP P+G M
Sbjct: 700 TSTNNSDVSSFNMQYSVYGGGGGTGGHPHAHVHHRGPALPKVKTPAGHVYEYIPHPLGHM 759

Query: 696 CQNPIYMQKEGDPVAYYRNLQEF-----SYSNLEEKKEEP-------------------- 730
           C+NPIY  +EG+ V  Y++L E      S  +L+++++ P                    
Sbjct: 760 CKNPIYRSREGNSVEDYKDLHELKVTYSSNHHLQQQQQPPPPPQQPQQQPPPQLQLQPGE 819

Query: 731 ---------ATPAYTISATELLEKQATP-REPELLYQNIAERVKELPSA----GLVHYNF 776
                     +PAY++S  E  E   +P ++ +  Y+ I E  K   +      L  Y  
Sbjct: 820 EERRESHHLRSPAYSVSTIEPREDLLSPVQDADRFYRGILEPDKHCSTTPAGNSLPEYPK 879

Query: 777 --CTLPKRQFAPSYESRRQNQ--------DRINKTVLYGTPRKCFVGQSKPNHPLLQAKP 826
             C+     F+P+Y+ RR +Q         R+ + VLY  P   FV  ++  +  L+AK 
Sbjct: 880 FPCSPAAYTFSPNYDLRRPHQYLHPGAGDSRLREPVLYSPPSAVFVEPNRNEYLELKAKL 939

Query: 827 QSEPDYLEVLEKQTAISQ 844
             EPDYLEVLEKQT  SQ
Sbjct: 940 NVEPDYLEVLEKQTTFSQ 957


>gi|27436867 slit and trk like 4 protein [Homo sapiens]
          Length = 837

 Score =  656 bits (1692), Expect = 0.0
 Identities = 373/868 (42%), Positives = 515/868 (59%), Gaps = 60/868 (6%)

Query: 5   VWFLSVLTVAGILQTESRKTAKDICKIRCLCEEKENVLNINCENKGFTTVSLLQPPQYRI 64
           +W   +L+            + +IC + C C   ENVL +NCE       + L+PP    
Sbjct: 3   LWLFLILSALISSTNADSDISVEICNV-CSCVSVENVLYVNCEKVSVYRPNQLKPPWSNF 61

Query: 65  YQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLEI 124
           Y L    N L  LYPN F+N+S+AV+LHLGNN LQ I  GAF GL  LK+LHLNNN+L+I
Sbjct: 62  YHLNFQNNFLNILYPNTFLNFSHAVSLHLGNNKLQNIEGGAFLGLSALKQLHLNNNELKI 121

Query: 125 LREDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRFVLLT 184
           LR DTFLG+E+LEYLQADYN I  IE GAF+KL+KLKVLILNDNL+  LP N+FRF  LT
Sbjct: 122 LRADTFLGIENLEYLQADYNLIKYIERGAFNKLHKLKVLILNDNLISFLPDNIFRFASLT 181

Query: 185 HLDLRGNRLKVMPFAGVLEHIGGIMEIQLEENPWNCTCDLLPLKAWLDTI--TVFVGEIV 242
           HLD+RGNR++ +P+ GVLEHIG ++E+QLE+NPWNC+CDLLPLKAWL+ +   +++GE +
Sbjct: 182 HLDIRGNRIQKLPYIGVLEHIGRVVELQLEDNPWNCSCDLLPLKAWLENMPYNIYIGEAI 241

Query: 243 CETPFRLHGKDVTQLTRQDLCPRKSASDSSQR---------------GSHADTHVQRLSP 287
           CETP  L+G+ + +  +Q+LCP  + SD   R               G    T + RL  
Sbjct: 242 CETPSDLYGRLLKETNKQELCPMGTGSDFDVRILPPSQLENGYTTPNGHTTQTSLHRLV- 300

Query: 288 TMNPALNPTRAPKASRPPKMRNRPTPRVTVSKDRQSFGPIMVYQTKSPVPLTCPSSCVCT 347
                   T+ PK + P K+      +   +++      I+ YQT+ P    CP+ C C 
Sbjct: 301 --------TKPPKTTNPSKISGIVAGKALSNRN---LSQIVSYQTRVPPLTPCPAPCFCK 349

Query: 348 SQSSDNGLNVNCQERKFTNISDLQPKPTSPKKLYLTGNYLQTVYKNDLLEYSSLDLLHLG 407
           +  SD GL+VNCQE+   ++S+L PKP + KKL++ GN ++ V  +D  ++  LDLLHLG
Sbjct: 350 THPSDLGLSVNCQEKNIQSMSELIPKPLNAKKLHVNGNSIKDVDVSDFTDFEGLDLLHLG 409

Query: 408 NNRIAVIQEGAFTNLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTF 467
           +N+I VI+   F NLT+LRRLYLNGN +E LYP +F GL +LQYLYLEYN+IKEI   TF
Sbjct: 410 SNQITVIKGDVFHNLTNLRRLYLNGNQIERLYPEIFSGLHNLQYLYLEYNLIKEISAGTF 469

Query: 468 DALINLQLLFLNNNLLRSLPDNIFGGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQ 527
           D++ NLQLL+LNNNLL+SLP  IF G  L RLNLRNN F +LPV GVLDQL +  QIDL+
Sbjct: 470 DSMPNLQLLYLNNNLLKSLPVYIFSGAPLARLNLRNNKFMYLPVSGVLDQLQSLTQIDLE 529

Query: 528 ENPWDCTCDIMGLKDWTEHANSPVIINEVTCESPAKHAGEILKFLGREAIC------PDS 581
            NPWDCTCD++ LK W E  +  +++ E+ CE+P + A   LK L  E +C      P +
Sbjct: 530 GNPWDCTCDLVALKLWVEKLSDGIVVKELKCETPVQFANIELKSLKNEILCPKLLNKPSA 589

Query: 582 PNLSDGTVLSMNHNTDTPRSLSVSPSSYPELHTEVPLSVLILGLLVVFILSVCFGAGLFV 641
           P  S    ++      TP     SP   P     VPLS+LIL +LVV IL+V     L V
Sbjct: 590 PFTSPAPAITFT----TPLGPIRSPPGGP-----VPLSILILSILVVLILTVFVAFCLLV 640

Query: 642 FVLKRRKGVPSVPRNTNNLDVSSFQLQYGSYNTETHDKTDGHVYNYIPPPVGQMCQNPIY 701
           FVL+R K          N D  S QLQ   ++ +T+ K       +IP  + QM ++   
Sbjct: 641 FVLRRNKKPTVKHEGLGNPDCGSMQLQLRKHDHKTNKKDGLSTEAFIPQTIEQMSKSHTC 700

Query: 702 MQKEGDPVAYYRNL--QEFSYSNLEEKKEE--PATPAYTISATELLEKQATPREPELLYQ 757
             KE +    + +   Q+    N+ +K+++         +S  + L++    R+  +  Q
Sbjct: 701 GLKESETGFMFSDPPGQKVVMRNVADKEKDLLHVDTRKRLSTIDELDELFPSRDSNVFIQ 760

Query: 758 NIAERVKELPSAGLVHYNFCTLPKRQFAPSYESRRQNQDRINKTVLYGTPRKCFVGQSKP 817
           N  E  KE  S G+  +     P++Q  P  +S+        K+++ G   K  V Q K 
Sbjct: 761 NFLESKKEYNSIGVSGFEI-RYPEKQ--PDKKSK--------KSLIGGNHSKIVVEQRKS 809

Query: 818 NHPLLQAKPQSEPDYLEVLEKQTAISQL 845
            +  L+AK QS PDYL+VLE+QTA++++
Sbjct: 810 EYFELKAKLQSSPDYLQVLEEQTALNKI 837


>gi|40217820 slit and trk like 3 protein [Homo sapiens]
          Length = 977

 Score =  652 bits (1682), Expect = 0.0
 Identities = 358/815 (43%), Positives = 492/815 (60%), Gaps = 66/815 (8%)

Query: 5   VWFLSVLTVA-----GILQTESRKTAKDICKIRCLCEEKENVLNINCENKGFTTVSLLQP 59
           +W + + T+A      I   E  +   + C   C CE KE++ +I+C++KGFT +S +  
Sbjct: 15  LWIILLSTIALGWTTPIPLIEDSEEIDEPCFDPCYCEVKESLFHIHCDSKGFTNISQITE 74

Query: 60  PQYRIYQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNN 119
              R ++L+L  N + +LY N F++ +NAV+++LGNN LQ+I+TGAF+GLK LKRL+L+ 
Sbjct: 75  FWSRPFKLYLQRNSMRKLYTNSFLHLNNAVSINLGNNALQDIQTGAFNGLKILKRLYLHE 134

Query: 120 NKLEILREDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFR 179
           NKL++ R DTFLGLESLEYLQADYN I  IE+GAF  L+KL+VLILNDNL+  LP+N+F+
Sbjct: 135 NKLDVFRNDTFLGLESLEYLQADYNVIKRIESGAFRNLSKLRVLILNDNLIPMLPTNLFK 194

Query: 180 FVLLTHLDLRGNRLKVMPFAGVLEHIG-GIMEIQLEENPWNCTCDLLPLKAWLDTI--TV 236
            V LTHLDLRGNRLKV+ + G+L+HIG  +ME+QLEENPWNCTC+++ LK+WL+ I  T 
Sbjct: 195 AVSLTHLDLRGNRLKVLFYRGMLDHIGRSLMELQLEENPWNCTCEIVQLKSWLERIPYTA 254

Query: 237 FVGEIVCETPFRLHGKDVTQLTRQDLCPRKSASD--SSQRGSHADTHVQRLSPTM----- 289
            VG+I CETPF  HGKD+ ++ + +LCP  S S+  +S    H+ +  +   PT      
Sbjct: 255 LVGDITCETPFHFHGKDLREIRKTELCPLLSDSEVEASLGIPHSSSSKENAWPTKPSSML 314

Query: 290 ---------------NPALNPTRAPKASRPPKMRNRPTPRVTVSKDRQSFGPIMVYQTKS 334
                          N    PT+ P+  RPP       P            PI  YQT+ 
Sbjct: 315 SSVHFTASSVEYKSSNKQPKPTKQPRTPRPPSTSQALYPGPNQP-------PIAPYQTRP 367

Query: 335 PVPLTCPSSCVCTSQSSDNGLNVNCQERKFTNISDLQPKPTSPKKLYLTGNYLQTVYKND 394
           P+P+ CP+ C C    +D GL VNC+ER F NIS+L P+P + KKLYL+ N +Q +Y++D
Sbjct: 368 PIPIICPTGCTCNLHINDLGLTVNCKERGFNNISELLPRPLNAKKLYLSSNLIQKIYRSD 427

Query: 395 LLEYSSLDLLHLGNNRIAVIQEGAFTNLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYL 454
              +SSLDLLHLGNNRI+ +Q+GAF NL +L+ L+LNGN +E L P MF GLQSL YLY 
Sbjct: 428 FWNFSSLDLLHLGNNRISYVQDGAFINLPNLKSLFLNGNDIEKLTPGMFRGLQSLHYLYF 487

Query: 455 EYNVIKEIKPLTFDALINLQLLFLNNNLLRSLPDNIFGGTALTRLNLRNNHFSHLPVKGV 514
           E+NVI+EI+P  F  + NL+LLFLNNNLLR+LP + F GT+L RLNLR N+F +LPV GV
Sbjct: 488 EFNVIREIQPAAFSLMPNLKLLFLNNNLLRTLPTDAFAGTSLARLNLRKNYFLYLPVAGV 547

Query: 515 LDQLPAFIQIDLQENPWDCTCDIMGLKDWTEHANSPVIINEVTCESPAKHAGEILKFLGR 574
           L+ L A +QIDL ENPWDCTCD++  K W E  +S  ++ +V C SP       ++ +  
Sbjct: 548 LEHLNAIVQIDLNENPWDCTCDLVPFKQWIETISSVSVVGDVLCRSPENLTHRDVRTIEL 607

Query: 575 EAICPD----SPNLSDGTVLSMNHNTDTPRSLSVSPSSYPELHTEVPLSVLILGLLVVFI 630
           E +CP+    +P          +H    P   S SP  +      VPLSVLIL LLV+F 
Sbjct: 608 EVLCPEMLHVAPAGESPAQPGDSHLIGAP--TSASPYEFSPPGGPVPLSVLILSLLVLFF 665

Query: 631 LSVCFGAGLFVFVL-KRRKGVPSVPRNTNNLDVSSFQLQY-----------------GSY 672
            +V   AGLF +VL +RRK +P   +    +D++  Q+Q                  G  
Sbjct: 666 SAVFVAAGLFAYVLRRRRKKLPFRSKRQEGVDLTGIQMQCHRLFEDGGGGGGGSGGGGRP 725

Query: 673 NTETHDKTD--GHVYNYIPPPVGQMCQNPIYMQKEGDPVAYYRNLQEFSYSNLEEKKEEP 730
              + +K    GHVY YIP PV QMC NPIY  +E + VA     +  S        + P
Sbjct: 726 TLSSPEKAPPVGHVYEYIPHPVTQMCNNPIYKPREEEEVAVSSAQEAGSAERGGPGTQPP 785

Query: 731 ATPAYTISATELLEKQATPREPELLYQNIAERVKE 765
                 + + +  E   TP+E    Y+ + E+ KE
Sbjct: 786 GMGEALLGSEQFAE---TPKENHSNYRTLLEKEKE 817



 Score = 35.4 bits (80), Expect = 0.22
 Identities = 30/87 (34%), Positives = 47/87 (54%), Gaps = 7/87 (8%)

Query: 761 ERVKELP-SAGLVHYNFCTLPKRQ----FAPSYESRRQNQD-RINKTVLYGTPRKCFVGQ 814
           ER +  P + G V   + T+PK +      P  +     QD R+ +T+L+   +     Q
Sbjct: 888 ERPQPAPCTVGFVDCLYGTVPKLKELHVHPPGMQYPDLQQDARLKETLLFSAGKGFTDHQ 947

Query: 815 SKPNHPL-LQAKPQSEPDYLEVLEKQT 840
           ++ +  L L+AK Q++PDYLEVLEK T
Sbjct: 948 TQKSDYLELRAKLQTKPDYLEVLEKTT 974


>gi|40217825 slit and trk like 6 [Homo sapiens]
          Length = 841

 Score =  587 bits (1514), Expect = e-167
 Identities = 346/860 (40%), Positives = 505/860 (58%), Gaps = 49/860 (5%)

Query: 5   VWFLSVLTVAGILQTESRKTAKDICKIRCLCEEKENVLNINCENKGFTTVSLLQPPQYRI 64
           +++ S+L    +       +++  C   C CEEK+  + INCE KG   VS +  P  R 
Sbjct: 7   LFYSSLLACISLHSQTPVLSSRGSCDSLCNCEEKDGTMLINCEAKGIKMVSEISVPPSRP 66

Query: 65  YQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLEI 124
           +QL L  N LT L+ N+F   +NA+++HLG N + +I  GAF+GL  LK+LH+N+N LEI
Sbjct: 67  FQLSLLNNGLTMLHTNDFSGLTNAISIHLGFNNIADIEIGAFNGLGLLKQLHINHNSLEI 126

Query: 125 LREDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRFVLLT 184
           L+EDTF GLE+LE+LQAD N+I+ IE  AFSKLN+LKVLILNDN + SLP N+FRFV LT
Sbjct: 127 LKEDTFHGLENLEFLQADNNFITVIEPSAFSKLNRLKVLILNDNAIESLPPNIFRFVPLT 186

Query: 185 HLDLRGNRLKVMPFAGVLEHIGGIMEIQLEENPWNCTCDLLPLKAWLDTITV--FVGEIV 242
           HLDLRGN+L+ +P+ G LEHIG I+++QLE+N W C CDLL LK WL+ +     +G++V
Sbjct: 187 HLDLRGNQLQTLPYVGFLEHIGRILDLQLEDNKWACNCDLLQLKTWLENMPPQSIIGDVV 246

Query: 243 CETPFRLHGKDVTQLTRQDLCPRKSASDSSQRGSHADTHVQRLSPTMNPALNPTRAPKAS 302
           C +P    G  +++L ++ +CP     +  +  S    H+   S ++N +   T+     
Sbjct: 247 CNSPPFFKGSILSRLKKESICPTPPVYEEHEDPS-GSLHLAATS-SINDSRMSTKTTSIL 304

Query: 303 RPPKMRNRPTPRVTVSKDRQSFGPIMVYQTKSPVPLTCPSSCVCTSQSSDNGLNVNCQER 362
           + P       P +T               T+ P P  CP  C C    S +GL ++CQER
Sbjct: 305 KLPTKAPGLIPYITKPS------------TQLPGPY-CPIPCNC-KVLSPSGLLIHCQER 350

Query: 363 KFTNISDLQPKPTSPKKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFTNL 422
              ++SDL+P P +P+KL L GN + ++ K+DL+EY +L++LHLGNNRI V++EG+F NL
Sbjct: 351 NIESLSDLRPPPQNPRKLILAGNIIHSLMKSDLVEYFTLEMLHLGNNRIEVLEEGSFMNL 410

Query: 423 TSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNNNL 482
           T L++LYLNGN+L  L   MF GL +L+YLYLEYN IKEI P TF+ +  L++L+LNNNL
Sbjct: 411 TRLQKLYLNGNHLTKLSKGMFLGLHNLEYLYLEYNAIKEILPGTFNPMPKLKVLYLNNNL 470

Query: 483 LRSLPDNIFGGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMGLKD 542
           L+ LP +IF G  LT++NL+ N F+HLPV  +LD L    QIDL++NPWDC+CD++GL+ 
Sbjct: 471 LQVLPPHIFSGVPLTKVNLKTNQFTHLPVSNILDDLDLLTQIDLEDNPWDCSCDLVGLQQ 530

Query: 543 WTEHANSPVIINEVTCESPAKHAGEILKFLGREAICP---DSPNLSDGTVLSMNHNTDTP 599
           W +  +   + +++ C SP     + LK L  E +CP   ++P++   T   M   T   
Sbjct: 531 WIQKLSKNTVTDDILCTSPGHLDKKELKALNSEILCPGLVNNPSMPTQTSYLM--VTTPA 588

Query: 600 RSLSVSPSSYPELHTEVPLSVLILGLLVVFILSVCFGAGLFVFVLKRRKGVPSVPRNTNN 659
            + + + +    L   VPLSVLILGLL++FI  V   AG+ V VL RR+       +   
Sbjct: 589 TTTNTADTILRSLTDAVPLSVLILGLLIMFITIVFCAAGIVVLVLHRRRRYKKKQVDEQM 648

Query: 660 LDVSSFQLQYGSY-NTETHDKTD---GHVY-NYIPPPVGQMCQNPIYMQKEGDPVAYYRN 714
            D S   LQY  Y +  TH  T+     +Y  ++  P+  + ++P +  K  +     RN
Sbjct: 649 RDNSPVHLQYSMYGHKTTHHTTERPSASLYEQHMVSPMVHVYRSPSFGPKHLEE-EEERN 707

Query: 715 LQEFS------YSNLEEKKEEPATPA-----YTISATELLEKQATPREPELLYQNIAERV 763
            +E S       S LE++   P T +      T  +TE L  Q    +   LY+NI E+ 
Sbjct: 708 EKEGSDAKHLQRSLLEQENHSPLTGSNMKYKTTNQSTEFLSFQ----DASSLYRNILEKE 763

Query: 764 KELPSAGLVHYNFCTLPKRQFAPSYESR---RQNQDRINKTVLYGTPRKCFVGQSKPNHP 820
           +EL   G+  Y    +   Q  P  E+       + ++ +T++Y  PRK  V Q+K  + 
Sbjct: 764 RELQQLGITEYLRKNI--AQLQPDMEAHYPGAHEELKLMETLMYSRPRKVLVEQTKNEYF 821

Query: 821 LLQAKPQSEPDYLEVLEKQT 840
            L+A   +EPDYLEVLE+QT
Sbjct: 822 ELKANLHAEPDYLEVLEQQT 841


>gi|40217817 slit and trk like 1 protein [Homo sapiens]
          Length = 696

 Score =  544 bits (1401), Expect = e-154
 Identities = 289/655 (44%), Positives = 405/655 (61%), Gaps = 26/655 (3%)

Query: 27  DICKIR-CLCEEKENVLNINCENKGFTTVSLLQPPQYRIYQLFLNGNLLTRLYPNEFVNY 85
           D+CK + C C E E  L+++CE KGFT++     P  + Y LFL+GN LTRL+PNEF N+
Sbjct: 22  DVCKEKICSCNEIEGDLHVDCEKKGFTSLQRFTAPTSQFYHLFLHGNSLTRLFPNEFANF 81

Query: 86  SNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLEILREDTFLGLESLEYLQADYNY 145
            NAV+LH+ NNGL EI  GAF GL+ +KRLH+NNNK++  R+ TFLGL+ LEYLQAD+N 
Sbjct: 82  YNAVSLHMENNGLHEIVPGAFLGLQLVKRLHINNNKIKSFRKQTFLGLDDLEYLQADFNL 141

Query: 146 ISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRFVLLTHLDLRGNRLKVMPFAGVLEHI 205
           +  I+ GAF  LNKL+VLILNDNL+ +LP+NVF++V +THLDLRGNRLK +P+  VLE I
Sbjct: 142 LRDIDPGAFQDLNKLEVLILNDNLISTLPANVFQYVPITHLDLRGNRLKTLPYEEVLEQI 201

Query: 206 GGIMEIQLEENPWNCTCDLLPLKAWLDTI--TVFVGEIVCETPFRLHGKDVTQLTRQDLC 263
            GI EI LE+NPW+CTCDLL LK WL+ I     +G +VCE P RL GKD+ + T QDLC
Sbjct: 202 PGIAEILLEDNPWDCTCDLLSLKEWLENIPKNALIGRVVCEAPTRLQGKDLNETTEQDLC 261

Query: 264 PRKSASDSSQRGSHA--DTHVQRLSPT----------MNPALNPTRAPKASRPPKMRNRP 311
           P K+  DSS     A  +T      PT            P   P    K     +++ RP
Sbjct: 262 PLKNRVDSSLPAPPAQEETFAPGPLPTPFKTNGQEDHATPGSAPNGGTKIPGNWQIKIRP 321

Query: 312 TPRVTVSKDRQSFGPIMVYQTKSPVPLTCPSSCVCTSQSSDNGLNVNCQERKFTNISDLQ 371
           T  +     R    P+          L CP  C C      +GL +NC  R  ++++DL+
Sbjct: 322 TAAIATGSSRNK--PL-------ANSLPCPGGCSC-DHIPGSGLKMNCNNRNVSSLADLK 371

Query: 372 PKPTSPKKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFTNLTSLRRLYLN 431
           PK ++ ++L+L  N + ++ K+  ++Y +L LL LGNN IA ++   F NL  LR LY++
Sbjct: 372 PKLSNVQELFLRDNKIHSIRKSHFVDYKNLILLDLGNNNIATVENNTFKNLLDLRWLYMD 431

Query: 432 GNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNNNLLRSLPDNIF 491
            NYL+ L    F GLQ+L+YL +EYN I+ I P TF+A+  L++L LNNNLLRSLP ++F
Sbjct: 432 SNYLDTLSREKFAGLQNLEYLNVEYNAIQLILPGTFNAMPKLRILILNNNLLRSLPVDVF 491

Query: 492 GGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMGLKDWTEHANSPV 551
            G +L++L+L NN+F +LPV GVLDQL + IQIDL  NPW+C+C I+  K W E   S V
Sbjct: 492 AGVSLSKLSLHNNYFMYLPVAGVLDQLTSIIQIDLHGNPWECSCTIVPFKQWAERLGSEV 551

Query: 552 IINEVTCESPAKHAGEILKFLGREAICPDSPNLSDGTVLSMNHNTDTPRSLSVSPSSYPE 611
           +++++ CE+P     +    L  + ICP        T+ S + N+          +SY +
Sbjct: 552 LMSDLKCETPVNFFRKDFMLLSNDEICPQLYARISPTLTSHSKNSTGLAETGTHSNSYLD 611

Query: 612 LHTEVPLSVLILGLLVVFILSVCFGAGLFVFVLKRRKGVPSVPRNTNNLDVSSFQ 666
             + V +SVL+ GLL+VF+ S     G+ VF+L+ RK       N++  +++S Q
Sbjct: 612 T-SRVSISVLVPGLLLVFVTSAFTVVGMLVFILRNRKRSKRRDANSSASEINSLQ 665


>gi|188528675 slit homolog 1 [Homo sapiens]
          Length = 1534

 Score =  146 bits (368), Expect = 9e-35
 Identities = 144/543 (26%), Positives = 212/543 (39%), Gaps = 105/543 (19%)

Query: 29  CKIRCLCEEKENVLNINCENKGFTTVSLLQPPQYRIYQLFLNGNLLTRLYPNEFVNYSNA 88
           C   C C        ++C   G   +    P      +L LNGN +TR++ N+F      
Sbjct: 34  CPALCTCTGT----TVDCHGTGLQAIPKNIPRNTE--RLELNGNNITRIHKNDFAGLKQL 87

Query: 89  VTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLEILREDTFLGLESLEYLQADYNYISA 148
             L L  N +  +  GAF  +K L+RL LN N+L +L E  F   ++L  L    N I A
Sbjct: 88  RVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHMLPELLFQNNQALSRLDLSENAIQA 147

Query: 149 IEAGAFSKLNKLKVLILNDNLLLSLPSNVFRFVL-LTHLDLRGNRLKVMPFAGVLEHIGG 207
           I   AF     LK L L+ N +  +    FR +  L  L L  N +  +P +    H+  
Sbjct: 148 IPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSS-FNHMPK 206

Query: 208 IMEIQLEENPWNCTCDLLPLKAWL---DTITVFVGEIVCETPFRLHGKDVTQLTRQDLCP 264
           +   +L  N   C C L  L  WL    TI +F     C  P  L G +V ++ + +   
Sbjct: 207 LRTFRLHSNHLFCDCHLAWLSQWLRQRPTIGLFT---QCSGPASLRGLNVAEVQKSEF-- 261

Query: 265 RKSASDSSQRGSHADTHVQRLSPTMNPALNPTRAPKASRPPKMRNRPTPRVTVSKDRQSF 324
             S S   + G                                     P  T+S      
Sbjct: 262 --SCSGQGEAGR-----------------------------------VPTCTLSSG---- 280

Query: 325 GPIMVYQTKSPVPLTCPSSCVCTSQSSDNGLNVNCQERKFTNISDLQPKPTSPKKLYLTG 384
                         +CP+ C C+     NG+ V+C+ +  T I    P+  +  +L L G
Sbjct: 281 --------------SCPAMCTCS-----NGI-VDCRGKGLTAIPANLPETMTEIRLELNG 320

Query: 385 NYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFTNLTSLRRLYLNGNYLEVLYPSMFD 444
             ++++       Y  L  + L NN+IA I   AF  L SL  L L GN +  L   +F 
Sbjct: 321 --IKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFG 378

Query: 445 GLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNNNLLRSLPDNIFGGTALTRLNLRNN 504
           GL +LQ L L  N I  I+P  F  L NL LL L +N ++SL                  
Sbjct: 379 GLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSL------------------ 420

Query: 505 HFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMGLKDWTEHANSPVIINEVTCESPAKH 564
                  KG    L A   + L +NP+ C C++  L D+     +P+  +   C SP + 
Sbjct: 421 ------AKGTFTSLRAIQTLHLAQNPFICDCNLKWLADFLR--TNPIETSGARCASPRRL 472

Query: 565 AGE 567
           A +
Sbjct: 473 ANK 475



 Score =  110 bits (275), Expect = 5e-24
 Identities = 114/454 (25%), Positives = 172/454 (37%), Gaps = 65/454 (14%)

Query: 29  CKIRCLCEEKENVLNINCENKGFTTVSLLQPPQYRIYQLFLNGNLLTRLYPNEFVNYSNA 88
           C   C C        ++C  KG T +    P      +L LNG  +  + P  F  Y   
Sbjct: 282 CPAMCTCSNGI----VDCRGKGLTAIPANLPETMTEIRLELNG--IKSIPPGAFSPYRKL 335

Query: 89  VTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLEILREDTFLGLESLEYLQADYNYISA 148
             + L NN + EI   AF GL++L  L L  NK+  L    F GL +L+ L  + N I+ 
Sbjct: 336 RRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANKINC 395

Query: 149 IEAGAFSKLNKLKVLILNDNLLLSLPSNVFRFVLLTHLDLRGNRLKVMPFAGVLEHIGGI 208
           I   AF  L  L +L L DN + SL                          G    +  I
Sbjct: 396 IRPDAFQDLQNLSLLSLYDNKIQSLAK------------------------GTFTSLRAI 431

Query: 209 MEIQLEENPWNCTCDLLPLKAWLDTITVFVGEIVCETPFRLHGKDVTQLTRQDLCPRKSA 268
             + L +NP+ C C+L  L  +L T  +      C +P RL  K + Q+       +K  
Sbjct: 432 QTLHLAQNPFICDCNLKWLADFLRTNPIETSGARCASPRRLANKRIGQIK-----SKKFR 486

Query: 269 SDSSQRGSHADTHVQRLSPTMNPALNPTRAPKASRPPKMRNRPTPRVTVSKDRQSFGPIM 328
             + ++     T   +L+   N  +                     V   K R     + 
Sbjct: 487 CSAKEQYFIPGTEDYQLNSECNSDV---------------------VCPHKCRCEANVVE 525

Query: 329 VYQTK-SPVPLTCPSSCVCTSQSSDNGLNVNCQERKFTNISDLQPKPTSPKKLYLTGNYL 387
               K + +P   P S           L +N  E      + +  K T  KK+ L+ N +
Sbjct: 526 CSSLKLTKIPERIPQSTA--------ELRLNNNEISILEATGMFKKLTHLKKINLSNNKV 577

Query: 388 QTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFTNLTSLRRLYLNGNYLEVLYPSMFDGLQ 447
             +        +S+  LHL  N++  I+ G F  L  LR L L  N +  ++   F GL+
Sbjct: 578 SEIEDGAFEGAASVSELHLTANQLESIRSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLR 637

Query: 448 SLQYLYLEYNVIKEIKPLTFDALINLQLLFLNNN 481
           +++ L L  N I  + P  FD L +L  L L  N
Sbjct: 638 NVRLLSLYDNQITTVSPGAFDTLQSLSTLNLLAN 671



 Score = 95.9 bits (237), Expect = 1e-19
 Identities = 83/296 (28%), Positives = 120/296 (40%), Gaps = 26/296 (8%)

Query: 340 CPSSCVCTSQSSDNGLNVNCQERKFTNISDLQPKPTSPKKLYLTGNYLQTVYKNDLLEYS 399
           CP+ C CT      G  V+C       I    P+ T  ++L L GN +  ++KND     
Sbjct: 34  CPALCTCT------GTTVDCHGTGLQAIPKNIPRNT--ERLELNGNNITRIHKNDFAGLK 85

Query: 400 SLDLLHLGNNRIAVIQEGAFTNLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVI 459
            L +L L  N+I  ++ GAF ++  L RL LN N L +L   +F   Q+L  L L  N I
Sbjct: 86  QLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHMLPELLFQNNQALSRLDLSENAI 145

Query: 460 KEIKPLTFDALINLQLLFLNNNLLRSLPDNIFGG-TALTRLNLRNNHFSHLPVKGVLDQL 518
           + I    F    +L+ L L+ N +  + +  F     L  L L NN+ + +PV    + +
Sbjct: 146 QAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSS-FNHM 204

Query: 519 PAFIQIDLQENPWDCTCDIMGLKDWTEHANSPVIINEVTCESPAKHAG----EILKF--- 571
           P      L  N   C C +  L  W      P I     C  PA   G    E+ K    
Sbjct: 205 PKLRTFRLHSNHLFCDCHLAWLSQWLR--QRPTIGLFTQCSGPASLRGLNVAEVQKSEFS 262

Query: 572 ------LGREAICPDSPNLSDGTVLSMNHNTD-TPRSLSVSPSSYPELHTEVPLSV 620
                  GR   C  S           N   D   + L+  P++ PE  TE+ L +
Sbjct: 263 CSGQGEAGRVPTCTLSSGSCPAMCTCSNGIVDCRGKGLTAIPANLPETMTEIRLEL 318



 Score = 92.0 bits (227), Expect = 2e-18
 Identities = 100/440 (22%), Positives = 182/440 (41%), Gaps = 59/440 (13%)

Query: 134 ESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRFVL-LTHLDLRGNR 192
           E++  ++ + N I +I  GAFS   KL+ + L++N +  +  + F+ +  L  L L GN+
Sbjct: 309 ETMTEIRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNK 368

Query: 193 LKVMPFAGVLEHIGGIMEIQLEENPWNCTCDLLPLKAWLDTITVFVGEIVCETPFRLHGK 252
           +  +P  GV   +  +  + L  N  NC    +   A+ D   + +          L+  
Sbjct: 369 ITDLP-RGVFGGLYTLQLLLLNANKINC----IRPDAFQDLQNLSL--------LSLYDN 415

Query: 253 DVTQLTRQDLCPRKSASDS--SQRGSHADTHVQRLSPTMNPALNPTRAPKASRPPKMRNR 310
            +  L +      ++      +Q     D +++ L+  +      T   + + P ++ N+
Sbjct: 416 KIQSLAKGTFTSLRAIQTLHLAQNPFICDCNLKWLADFLRTNPIETSGARCASPRRLANK 475

Query: 311 PTPRVTVSKDR-----QSFGP-IMVYQTKSPV--PLTCPSSCVCTSQSSDNGLNVNCQER 362
              ++   K R     Q F P    YQ  S     + CP  C C +        V C   
Sbjct: 476 RIGQIKSKKFRCSAKEQYFIPGTEDYQLNSECNSDVVCPHKCRCEANV------VECSSL 529

Query: 363 KFTNISDLQPKPTSPKKLYLTGNYLQTVYKNDLLE-YSSLDLLHLGNNRIAVIQEGAFTN 421
           K T I +  P+ T+  +L L  N +  +    + +  + L  ++L NN+++ I++GAF  
Sbjct: 530 KLTKIPERIPQSTA--ELRLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEG 587

Query: 422 LTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNNN 481
             S+  L+L  N LE +   MF GL  L+ L L  N I  I   +F  L N++LL L +N
Sbjct: 588 AASVSELHLTANQLESIRSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDN 647

Query: 482 LLRSLPDNIFGGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMGLK 541
            + ++                          G  D L +   ++L  NP++C C +  L 
Sbjct: 648 QITTVSP------------------------GAFDTLQSLSTLNLLANPFNCNCQLAWLG 683

Query: 542 DWTEHANSPVIINEVTCESP 561
            W       ++     C++P
Sbjct: 684 GWLR--KRKIVTGNPRCQNP 701



 Score = 88.6 bits (218), Expect = 2e-17
 Identities = 106/426 (24%), Positives = 167/426 (39%), Gaps = 67/426 (15%)

Query: 18  QTESRKTAKDICKIRCLCEEKENVLNINCENKGFTTVSLLQPPQYRIYQLFLNGNLLTRL 77
           Q  S   +  +C  +C CE   NV  + C +   T +    P      +L LN N ++ L
Sbjct: 502 QLNSECNSDVVCPHKCRCEA--NV--VECSSLKLTKIPERIPQSTA--ELRLNNNEISIL 555

Query: 78  YPNE-FVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLEILREDTFLGLESL 136
                F   ++   ++L NN + EI  GAF G  ++  LHL  N+LE +R   F GL+ L
Sbjct: 556 EATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESIRSGMFRGLDGL 615

Query: 137 EYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRFVLLTHLDLRGNRLKVM 196
             L    N IS I   +F+ L  +++L L DN + ++                       
Sbjct: 616 RTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVS---------------------- 653

Query: 197 PFAGVLEHIGGIMEIQLEENPWNCTCDLLPLKAWLDTITVFVGEIVCETPFRLHGKDVTQ 256
              G  + +  +  + L  NP+NC C L  L  WL    +  G   C+ P  L      Q
Sbjct: 654 --PGAFDTLQSLSTLNLLANPFNCNCQLAWLGGWLRKRKIVTGNPRCQNPDFLR-----Q 706

Query: 257 LTRQDLC-PRKSASDSSQRGSHADTHVQRLSPTMNPALNPTRAPKASRPPKMRNRPTPR- 314
           +  QD+  P     +  + G      + R       A   T    +++  +   +  P+ 
Sbjct: 707 IPLQDVAFPDFRCEEGQEEGG----CLPRPQCPQECACLDTVVRCSNKHLRALPKGIPKN 762

Query: 315 -VTVSKDRQSF----GPIMVYQTKSPVPLTCPSSCVCTSQSSDNGLNVNCQERKFTNISD 369
              +  D   F    G +  ++    V L            S+N ++ +     FTN+S 
Sbjct: 763 VTELYLDGNQFTLVPGQLSTFKYLQLVDL------------SNNKIS-SLSNSSFTNMSQ 809

Query: 370 LQPKPTSPKKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFTNLTSLRRLY 429
           L         L L+ N LQ +         SL LL L  N I+ +QEG F ++TSL  L 
Sbjct: 810 L-------TTLILSYNALQCIPPLAFQGLRSLRLLSLHGNDISTLQEGIFADVTSLSHLA 862

Query: 430 LNGNYL 435
           +  N L
Sbjct: 863 IGANPL 868



 Score = 70.1 bits (170), Expect = 8e-12
 Identities = 86/354 (24%), Positives = 144/354 (40%), Gaps = 29/354 (8%)

Query: 134 ESLEYLQADYNYISAIEA-GAFSKLNKLKVLILNDNLLLSLPSNVFRFVL-LTHLDLRGN 191
           +S   L+ + N IS +EA G F KL  LK + L++N +  +    F     ++ L L  N
Sbjct: 540 QSTAELRLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTAN 599

Query: 192 RLKVMPFAGVLEHIGGIMEIQLEENPWNCTCDLLPLKAWLDTITVFVGEIVCETPFRLHG 251
           +L+ +  +G+   + G+  + L  N  +C  +        D+ T      +      L+ 
Sbjct: 600 QLESIR-SGMFRGLDGLRTLMLRNNRISCIHN--------DSFTGLRNVRLLS----LYD 646

Query: 252 KDVTQLTRQDLCPRKSASDSSQRGSHADTHVQR--LSPTMNPALNPTRAPKASRPPKMRN 309
             +T ++       +S S  +   +  + + Q   L   +      T  P+   P  +R 
Sbjct: 647 NQITTVSPGAFDTLQSLSTLNLLANPFNCNCQLAWLGGWLRKRKIVTGNPRCQNPDFLRQ 706

Query: 310 RPTPRVTVSKDRQSFGPIMVYQTKSPVPLTCPSSCVCTSQSSDNGLNVNCQERKFTNISD 369
            P   V     R   G         P    CP  C C          V C  +    +  
Sbjct: 707 IPLQDVAFPDFRCEEGQEEGGCLPRP---QCPQECACLDTV------VRCSNKHLRALPK 757

Query: 370 LQPKPTSPKKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFTNLTSLRRLY 429
             PK  +  +LYL GN   T+    L  +  L L+ L NN+I+ +   +FTN++ L  L 
Sbjct: 758 GIPKNVT--ELYLDGNQF-TLVPGQLSTFKYLQLVDLSNNKISSLSNSSFTNMSQLTTLI 814

Query: 430 LNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNNNLL 483
           L+ N L+ + P  F GL+SL+ L L  N I  ++   F  + +L  L +  N L
Sbjct: 815 LSYNALQCIPPLAFQGLRSLRLLSLHGNDISTLQEGIFADVTSLSHLAIGANPL 868



 Score = 50.4 bits (119), Expect = 7e-06
 Identities = 45/167 (26%), Positives = 65/167 (38%), Gaps = 27/167 (16%)

Query: 87  NAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLEILREDTFLGLESLEYLQADYNYI 146
           N   L+L  N    +  G  S  K L+ + L+NNK+  L   +F  +  L  L   YN +
Sbjct: 762 NVTELYLDGNQFTLV-PGQLSTFKYLQLVDLSNNKISSLSNSSFTNMSQLTTLILSYNAL 820

Query: 147 SAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRFVL-LTHLDLRGNRLKVMPFAGVLEHI 205
             I   AF  L  L++L L+ N + +L   +F  V  L+HL                   
Sbjct: 821 QCIPPLAFQGLRSLRLLSLHGNDISTLQEGIFADVTSLSHL------------------- 861

Query: 206 GGIMEIQLEENPWNCTCDLLPLKAWLDTITVFVGEIVCETPFRLHGK 252
                  +  NP  C C L  L +W+ T     G   C  P  + GK
Sbjct: 862 ------AIGANPLYCDCHLRWLSSWVKTGYKEPGIARCAGPQDMEGK 902


>gi|4759146 slit homolog 2 [Homo sapiens]
          Length = 1529

 Score =  134 bits (336), Expect = 5e-31
 Identities = 145/567 (25%), Positives = 214/567 (37%), Gaps = 102/567 (17%)

Query: 2   LSGVWFLSVLTVAGILQTESRKTAKDICKIRCLCEEKENVLNINCENKGFTTVSLLQPPQ 61
           + GV +  +    G++     K A   C  +C C        ++C      +V    P  
Sbjct: 1   MRGVGWQMLSLSLGLVLAILNKVAPQACPAQCSCSGS----TVDCHGLALRSVPRNIPRN 56

Query: 62  YRIYQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNK 121
               +L LNGN +TR+   +F    +   L L  N +  I  GAF  LK L+RL LN N 
Sbjct: 57  TE--RLDLNGNNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDLKELERLRLNRNH 114

Query: 122 LEILREDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRFV 181
           L++  E  FLG   L  L    N I AI   AF     +K L L+ N +  +    FR +
Sbjct: 115 LQLFPELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIEDGAFRAL 174

Query: 182 L-LTHLDLRGNRLKVMPFAGVLEHIGGIMEIQLEENPWNCTCDLLPLKAWLDTITVFVGE 240
             L  L L  N +  +  A    H+  +   +L  N   C C L    AWL         
Sbjct: 175 RDLEVLTLNNNNITRLSVAS-FNHMPKLRTFRLHSNNLYCDCHL----AWL--------- 220

Query: 241 IVCETPFRLHGKDVTQLTRQDLCPRKSASDSSQRGSHADTHVQRLSPTMNPALNPTRAPK 300
                                       SD  ++      + Q + P+     N     K
Sbjct: 221 ----------------------------SDWLRQRPRVGLYTQCMGPSHLRGHNVAEVQK 252

Query: 301 ASRPPKMRNRPTPRVTVSKDRQSFGPIMVYQTKSPVPLTCPSSCVCTSQSSDNGLNVNCQ 360
                        R  V    QSF         S   L CP++C C++        V+C+
Sbjct: 253 -------------REFVCSGHQSF------MAPSCSVLHCPAACTCSNNI------VDCR 287

Query: 361 ERKFTNISDLQPKPTSPKKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFT 420
            +  T I    P+  +  ++ L  N ++ +       Y  L  + L NN+I+ +   AF 
Sbjct: 288 GKGLTEIPTNLPETIT--EIRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQ 345

Query: 421 NLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNN 480
            L SL  L L GN +  L  S+F+GL SLQ L L  N I  ++   F  L NL LL L +
Sbjct: 346 GLRSLNSLVLYGNKITELPKSLFEGLFSLQLLLLNANKINCLRVDAFQDLHNLNLLSLYD 405

Query: 481 NLLRSLPDNIFGGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMGL 540
           N L+++                         KG    L A   + L +NP+ C C +  L
Sbjct: 406 NKLQTI------------------------AKGTFSPLRAIQTMHLAQNPFICDCHLKWL 441

Query: 541 KDWTEHANSPVIINEVTCESPAKHAGE 567
            D+  H N P+  +   C SP + A +
Sbjct: 442 ADYL-HTN-PIETSGARCTSPRRLANK 466



 Score =  100 bits (250), Expect = 4e-21
 Identities = 110/434 (25%), Positives = 168/434 (38%), Gaps = 47/434 (10%)

Query: 29  CKIRCLCEEKENVLNINCENKGFTTVSLLQPPQYRIYQLFLNGNLLTRLYPNEFVNYSNA 88
           C   C C    N+  ++C  KG T +    P    I ++ L  N +  + P  F  Y   
Sbjct: 273 CPAACTCSN--NI--VDCRGKGLTEIPTNLPET--ITEIRLEQNTIKVIPPGAFSPYKKL 326

Query: 89  VTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLEILREDTFLGLESLEYLQADYNYISA 148
             + L NN + E+   AF GL++L  L L  NK+  L +  F GL SL+ L  + N I+ 
Sbjct: 327 RRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKITELPKSLFEGLFSLQLLLLNANKINC 386

Query: 149 IEAGAFSKLNKLKVLILNDNLLLSLPSNVFRFVLLTHLDLRGNRLKVMPFAGVLEHIGGI 208
           +   AF  L+ L +L L DN L ++                          G    +  I
Sbjct: 387 LRVDAFQDLHNLNLLSLYDNKLQTIAK------------------------GTFSPLRAI 422

Query: 209 MEIQLEENPWNCTCDLLPLKAWLDTITVFVGEIVCETPFRLHGKDVTQLTRQDLCPRKSA 268
             + L +NP+ C C L  L  +L T  +      C +P RL  K + Q+  +        
Sbjct: 423 QTMHLAQNPFICDCHLKWLADYLHTNPIETSGARCTSPRRLANKRIGQIKSKKF------ 476

Query: 269 SDSSQRGSHADTHVQRLSPTMNPALNPTRAPKASRPPKMRNRPTPRVTVSKDRQSFGPIM 328
                R S  + +    +      L+       + P K R   T  V  S  + +  P  
Sbjct: 477 -----RCSAKEQYFIPGTEDYRSKLSGDCFADLACPEKCRCEGT-TVDCSNQKLNKIPEH 530

Query: 329 VYQTKSPVPLTCPSSCVCTSQSSDNGL----NVNCQERKFTNISDLQPKPTS-PKKLYLT 383
           + Q  + + L      V  +      L     +N    K T+I +   +  S   ++ LT
Sbjct: 531 IPQYTAELRLNNNEFTVLEATGIFKKLPQLRKINFSNNKITDIEEGAFEGASGVNEILLT 590

Query: 384 GNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFTNLTSLRRLYLNGNYLEVLYPSMF 443
            N L+ V         SL  L L +NRI  +   +F  L+S+R L L  N +  + P  F
Sbjct: 591 SNRLENVQHKMFKGLESLKTLMLRSNRITCVGNDSFIGLSSVRLLSLYDNQITTVAPGAF 650

Query: 444 DGLQSLQYLYLEYN 457
           D L SL  L L  N
Sbjct: 651 DTLHSLSTLNLLAN 664



 Score = 93.2 bits (230), Expect = 9e-19
 Identities = 100/442 (22%), Positives = 183/442 (41%), Gaps = 61/442 (13%)

Query: 134 ESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRFVL-LTHLDLRGNR 192
           E++  ++ + N I  I  GAFS   KL+ + L++N +  L  + F+ +  L  L L GN+
Sbjct: 300 ETITEIRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNK 359

Query: 193 LKVMPFAGVLEHIGGIMEIQLEENPWNCTCDLLPLKAWLDTITVFVGEIVCETPFRLHGK 252
           +  +P   + E +  +  + L  N  NC    L + A+ D   + +          L+  
Sbjct: 360 ITELP-KSLFEGLFSLQLLLLNANKINC----LRVDAFQDLHNLNL--------LSLYDN 406

Query: 253 DVTQLTRQDLCPRKSASDS--SQRGSHADTHVQRLSPTMNPALNPTRAPKASRPPKMRNR 310
            +  + +    P ++      +Q     D H++ L+  ++     T   + + P ++ N+
Sbjct: 407 KLQTIAKGTFSPLRAIQTMHLAQNPFICDCHLKWLADYLHTNPIETSGARCTSPRRLANK 466

Query: 311 PTPRVTVSKDR-----QSFGP-IMVYQTKSP----VPLTCPSSCVCTSQSSDNGLNVNCQ 360
              ++   K R     Q F P    Y++K        L CP  C C       G  V+C 
Sbjct: 467 RIGQIKSKKFRCSAKEQYFIPGTEDYRSKLSGDCFADLACPEKCRC------EGTTVDCS 520

Query: 361 ERKFTNISDLQPKPTSPKKLYLTGNYLQTVYKNDLLE-YSSLDLLHLGNNRIAVIQEGAF 419
            +K   I +  P+ T+  +L L  N    +    + +    L  ++  NN+I  I+EGAF
Sbjct: 521 NQKLNKIPEHIPQYTA--ELRLNNNEFTVLEATGIFKKLPQLRKINFSNNKITDIEEGAF 578

Query: 420 TNLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLN 479
              + +  + L  N LE +   MF GL+SL+ L L  N I  +   +F  L +++LL L 
Sbjct: 579 EGASGVNEILLTSNRLENVQHKMFKGLESLKTLMLRSNRITCVGNDSFIGLSSVRLLSLY 638

Query: 480 NNLLRSLPDNIFGGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMG 539
           +N + ++                          G  D L +   ++L  NP++C C +  
Sbjct: 639 DNQITTV------------------------APGAFDTLHSLSTLNLLANPFNCNCYLAW 674

Query: 540 LKDWTEHANSPVIINEVTCESP 561
           L +W       ++     C+ P
Sbjct: 675 LGEWLR--KKRIVTGNPRCQKP 694



 Score = 90.5 bits (223), Expect = 6e-18
 Identities = 80/295 (27%), Positives = 124/295 (42%), Gaps = 25/295 (8%)

Query: 337 PLTCPSSCVCTSQSSD-NGLNVNCQERKFTNISDLQPKPTSPKKLYLTGNYLQTVYKNDL 395
           P  CP+ C C+  + D +GL +    R           P + ++L L GN +  + K D 
Sbjct: 25  PQACPAQCSCSGSTVDCHGLALRSVPRNI---------PRNTERLDLNGNNITRITKTDF 75

Query: 396 LEYSSLDLLHLGNNRIAVIQEGAFTNLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLE 455
                L +L L  N+I+ I+ GAF +L  L RL LN N+L++    +F G   L  L L 
Sbjct: 76  AGLRHLRVLQLMENKISTIERGAFQDLKELERLRLNRNHLQLFPELLFLGTAKLYRLDLS 135

Query: 456 YNVIKEIKPLTFDALINLQLLFLNNNLLRSLPDNIFGGTA-LTRLNLRNNHFSHLPVKGV 514
            N I+ I    F   ++++ L L+ N +  + D  F     L  L L NN+ + L V   
Sbjct: 136 ENQIQAIPRKAFRGAVDIKNLQLDYNQISCIEDGAFRALRDLEVLTLNNNNITRLSVAS- 194

Query: 515 LDQLPAFIQIDLQENPWDCTCDIMGLKDWTEHANSPVIINEVTCESPAKHAG-EILKFLG 573
            + +P      L  N   C C +  L DW      P +     C  P+   G  + +   
Sbjct: 195 FNHMPKLRTFRLHSNNLYCDCHLAWLSDWLR--QRPRVGLYTQCMGPSHLRGHNVAEVQK 252

Query: 574 REAIC--------PDSPNLSDGTVLSMNHNTDTPR--SLSVSPSSYPELHTEVPL 618
           RE +C        P    L      + ++N    R   L+  P++ PE  TE+ L
Sbjct: 253 REFVCSGHQSFMAPSCSVLHCPAACTCSNNIVDCRGKGLTEIPTNLPETITEIRL 307



 Score = 83.2 bits (204), Expect = 9e-16
 Identities = 94/409 (22%), Positives = 159/409 (38%), Gaps = 55/409 (13%)

Query: 29  CKIRCLCEEKENVLNINCENKGFTTVSLLQPPQYRIYQLFLNGNLLTRLYPNE-FVNYSN 87
           C  +C CE       ++C N+    +     PQY   +L LN N  T L     F     
Sbjct: 506 CPEKCRCEGT----TVDCSNQKLNKIPE-HIPQYTA-ELRLNNNEFTVLEATGIFKKLPQ 559

Query: 88  AVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLEILREDTFLGLESLEYLQADYNYIS 147
              ++  NN + +I  GAF G   +  + L +N+LE ++   F GLESL+ L    N I+
Sbjct: 560 LRKINFSNNKITDIEEGAFEGASGVNEILLTSNRLENVQHKMFKGLESLKTLMLRSNRIT 619

Query: 148 AIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRFVLLTHLDLRGNRLKVMPFAGVLEHIGG 207
            +   +F  L+ +++L L DN + ++                          G  + +  
Sbjct: 620 CVGNDSFIGLSSVRLLSLYDNQITTVA------------------------PGAFDTLHS 655

Query: 208 IMEIQLEENPWNCTCDLLPLKAWLDTITVFVGEIVCETPFRLHGKDVTQLTRQDL-CPRK 266
           +  + L  NP+NC C L  L  WL    +  G   C+ P+ L    +  +  QD  C   
Sbjct: 656 LSTLNLLANPFNCNCYLAWLGEWLRKKRIVTGNPRCQKPYFLKEIPIQDVAIQDFTCDDG 715

Query: 267 SASDSSQRGSHADTHVQRLSPTMNPALNPTRAPKASRPPKMRNRPTPRVTVSKDRQSFGP 326
           +  +S    S   T    L   +  +    +       PK   R    + +  ++ +  P
Sbjct: 716 NDDNSCSPLSRCPTECTCLDTVVRCSNKGLKV-----LPKGIPRDVTELYLDGNQFTLVP 770

Query: 327 IMVYQTKSPVPLTCPSSCVCTSQSSDNGLNVNCQERKFTNISDLQPKPTSPKKLYLTGNY 386
             +   K    +   ++ + T              + F+N++ L         L L+ N 
Sbjct: 771 KELSNYKHLTLIDLSNNRIST-----------LSNQSFSNMTQL-------LTLILSYNR 812

Query: 387 LQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFTNLTSLRRLYLNGNYL 435
           L+ +         SL LL L  N I+V+ EGAF +L++L  L +  N L
Sbjct: 813 LRCIPPRTFDGLKSLRLLSLHGNDISVVPEGAFNDLSALSHLAIGANPL 861



 Score = 75.5 bits (184), Expect = 2e-13
 Identities = 95/377 (25%), Positives = 149/377 (39%), Gaps = 61/377 (16%)

Query: 115 LHLNNNKLEILRED-TFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSL 173
           L LNNN+  +L     F  L  L  +    N I+ IE GAF   + +  ++L  N L ++
Sbjct: 538 LRLNNNEFTVLEATGIFKKLPQLRKINFSNNKITDIEEGAFEGASGVNEILLTSNRLENV 597

Query: 174 PSNVFRFV-LLTHLDLRGNRLKVMPFAGVLEHIGGIMEIQLEENPWNCTCDLLPLKAWLD 232
              +F+ +  L  L LR NR+  +     +    G+  ++L                   
Sbjct: 598 QHKMFKGLESLKTLMLRSNRITCVGNDSFI----GLSSVRL------------------- 634

Query: 233 TITVFVGEIVCETPFRLHGKDVTQLTRQDLCPRKSASDSSQRGSHADTHVQRLSPTMNPA 292
            ++++  +I    P              D     S  +      + + ++  L   +   
Sbjct: 635 -LSLYDNQITTVAPGAF-----------DTLHSLSTLNLLANPFNCNCYLAWLGEWLRKK 682

Query: 293 LNPTRAPKASRPPKMRNRPTPRVTVSKDRQSFGPIMVYQTKSPVPLT-CPSSCVCTS--- 348
              T  P+  +P  ++  P   V +    Q F         S  PL+ CP+ C C     
Sbjct: 683 RIVTGNPRCQKPYFLKEIPIQDVAI----QDFTCDDGNDDNSCSPLSRCPTECTCLDTVV 738

Query: 349 QSSDNGLNVNCQERKFTNISDLQPK--PTSPKKLYLTGNYLQTVYKNDLLEYSSLDLLHL 406
           + S+ GL V              PK  P    +LYL GN    V K +L  Y  L L+ L
Sbjct: 739 RCSNKGLKV-------------LPKGIPRDVTELYLDGNQFTLVPK-ELSNYKHLTLIDL 784

Query: 407 GNNRIAVIQEGAFTNLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLT 466
            NNRI+ +   +F+N+T L  L L+ N L  + P  FDGL+SL+ L L  N I  +    
Sbjct: 785 SNNRISTLSNQSFSNMTQLLTLILSYNRLRCIPPRTFDGLKSLRLLSLHGNDISVVPEGA 844

Query: 467 FDALINLQLLFLNNNLL 483
           F+ L  L  L +  N L
Sbjct: 845 FNDLSALSHLAIGANPL 861



 Score = 58.9 bits (141), Expect = 2e-08
 Identities = 50/176 (28%), Positives = 79/176 (44%), Gaps = 11/176 (6%)

Query: 397 EYSSLD-LLHLGNNRIAVIQEGAFTNLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLE 455
           E + LD ++   N  + V+ +G   ++T L   YL+GN    L P      + L  + L 
Sbjct: 730 ECTCLDTVVRCSNKGLKVLPKGIPRDVTEL---YLDGNQF-TLVPKELSNYKHLTLIDLS 785

Query: 456 YNVIKEIKPLTFDALINLQLLFLNNNLLRSLPDNIFGGT-ALTRLNLRNNHFSHLPVKGV 514
            N I  +   +F  +  L  L L+ N LR +P   F G  +L  L+L  N  S +P +G 
Sbjct: 786 NNRISTLSNQSFSNMTQLLTLILSYNRLRCIPPRTFDGLKSLRLLSLHGNDISVVP-EGA 844

Query: 515 LDQLPAFIQIDLQENPWDCTCDIMGLKDWTE-HANSPVIINEVTCESPAKHAGEIL 569
            + L A   + +  NP  C C++  L DW +     P I     C  P + A ++L
Sbjct: 845 FNDLSALSHLAIGANPLYCDCNMQWLSDWVKSEYKEPGI---ARCAGPGEMADKLL 897



 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 50/224 (22%), Positives = 77/224 (34%), Gaps = 55/224 (24%)

Query: 29  CKIRCLCEEKENVLNINCENKGFTTVSLLQPPQYRIYQLFLNGNLLTRLYPNEFVNYSNA 88
           C   C C +      + C NKG   +    P    + +L+L+GN  T L P E  NY   
Sbjct: 727 CPTECTCLDTV----VRCSNKGLKVLPKGIPRD--VTELYLDGNQFT-LVPKELSNY--- 776

Query: 89  VTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLEILREDTFLGLESLEYLQADYNYISA 148
                                K L  + L+NN++  L   +F  +  L  L   YN +  
Sbjct: 777 ---------------------KHLTLIDLSNNRISTLSNQSFSNMTQLLTLILSYNRLRC 815

Query: 149 IEAGAFSKLNKLKVLILNDNLLLSLPSNVFRFVLLTHLDLRGNRLKVMPFAGVLEHIGGI 208
           I    F  L  L++L                        L GN + V+P  G    +  +
Sbjct: 816 IPPRTFDGLKSLRLL-----------------------SLHGNDISVVP-EGAFNDLSAL 851

Query: 209 MEIQLEENPWNCTCDLLPLKAWLDTITVFVGEIVCETPFRLHGK 252
             + +  NP  C C++  L  W+ +     G   C  P  +  K
Sbjct: 852 SHLAIGANPLYCDCNMQWLSDWVKSEYKEPGIARCAGPGEMADK 895


>gi|11321571 slit homolog 3 [Homo sapiens]
          Length = 1523

 Score =  132 bits (333), Expect = 1e-30
 Identities = 136/564 (24%), Positives = 211/564 (37%), Gaps = 149/564 (26%)

Query: 29  CKIRCLCEEKENVLNINCENKGFTTVSLLQPPQYRIYQLFLNGNLLTRLYPNEFVNYSNA 88
           C  +C C    +  +++C   G   V    P      +L L+ N +TR+   +F    N 
Sbjct: 34  CPTKCTC----SAASVDCHGLGLRAVPRGIPRNAE--RLDLDRNNITRITKMDFAGLKNL 87

Query: 89  VTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLEILRE--------------------- 127
             LHL +N +  I  GAF  LK L+RL LN NKL++L E                     
Sbjct: 88  RVLHLEDNQVSVIERGAFQDLKQLERLRLNKNKLQVLPELLFQSTPKLTRLDLSENQIQG 147

Query: 128 ---DTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRFVLLT 184
                F G+  ++ LQ D N+IS IE GAF  L  L++L LN+N       N+ R ++ +
Sbjct: 148 IPRKAFRGITDVKNLQLDNNHISCIEDGAFRALRDLEILTLNNN-------NISRILVTS 200

Query: 185 HLDLRGNRLKVMPFAGVLEHIGGIMEIQLEENPWNCTCDLLPLKAWLDTITVFVGEIVCE 244
                              H+  I  ++L  N   C C L  L  WL          +C 
Sbjct: 201 -----------------FNHMPKIRTLRLHSNHLYCDCHLAWLSDWLRQRRTVGQFTLCM 243

Query: 245 TPFRLHGKDVTQLTRQD-LCPRKSASDSSQRGSHADTHVQRLSPTMNPALNPTRAPKASR 303
            P  L G +V  + +++ +CP                                 AP +  
Sbjct: 244 APVHLRGFNVADVQKKEYVCP---------------------------------APHSEP 270

Query: 304 PPKMRNRPTPRVTVSKDRQSFGPIMVYQTKSPVPLTCPSSCVCTSQSSDNGLNVNCQERK 363
           P    N                         P P TC ++             V+C+ + 
Sbjct: 271 PSCNAN---------------------SISCPSPCTCSNNI------------VDCRGKG 297

Query: 364 FTNISDLQPKPTSPKKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFTNLT 423
              I      P    ++ L  N ++ +      +Y  L  + +  N+I+ I   AF  L 
Sbjct: 298 LMEIP--ANLPEGIVEIRLEQNSIKAIPAGAFTQYKKLKRIDISKNQISDIAPDAFQGLK 355

Query: 424 SLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNNNLL 483
           SL  L L GN +  +   +FDGL SLQ L L  N I  ++  TF  L NL LL L +N L
Sbjct: 356 SLTSLVLYGNKITEIAKGLFDGLVSLQLLLLNANKINCLRVNTFQDLQNLNLLSLYDNKL 415

Query: 484 RSLPDNIFGGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMGLKDW 543
           +++                         KG+   L +   + L +NP+ C C +  L D+
Sbjct: 416 QTIS------------------------KGLFAPLQSIQTLHLAQNPFVCDCHLKWLADY 451

Query: 544 TEHANSPVIINEVTCESPAKHAGE 567
            +  ++P+  +   C SP + A +
Sbjct: 452 LQ--DNPIETSGARCSSPRRLANK 473



 Score = 97.8 bits (242), Expect = 4e-20
 Identities = 101/434 (23%), Positives = 183/434 (42%), Gaps = 53/434 (12%)

Query: 134 ESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRFVL-LTHLDLRGNR 192
           E +  ++ + N I AI AGAF++  KLK + ++ N +  +  + F+ +  LT L L GN+
Sbjct: 307 EGIVEIRLEQNSIKAIPAGAFTQYKKLKRIDISKNQISDIAPDAFQGLKSLTSLVLYGNK 366

Query: 193 LKVMPFAGVLEHIGGIMEIQLEENPWNCTCDLLPLKAWLDTITVFVGEIVCETPFRLHGK 252
           +  +   G+ + +  +  + L  N  NC    L +  + D   + +          L+  
Sbjct: 367 ITEIA-KGLFDGLVSLQLLLLNANKINC----LRVNTFQDLQNLNL--------LSLYDN 413

Query: 253 DVTQLTRQDLCPRKSASDS--SQRGSHADTHVQRLSPTMNPALNPTRAPKASRPPKMRNR 310
            +  +++    P +S      +Q     D H++ L+  +      T   + S P ++ N+
Sbjct: 414 KLQTISKGLFAPLQSIQTLHLAQNPFVCDCHLKWLADYLQDNPIETSGARCSSPRRLANK 473

Query: 311 PTPRVTVSKDRQSFGPIMVYQTKSP--VPLTCPSSCVCTSQSSDNGLNVNCQERKFTNIS 368
              ++   K R S       +  S   + L CP  C C       G  V+C  +K   I 
Sbjct: 474 RISQIKSKKFRCSGSEDYRSRFSSECFMDLVCPEKCRC------EGTIVDCSNQKLVRIP 527

Query: 369 DLQPKPTSPKKLYLTGNYLQTVYKNDLLE-YSSLDLLHLGNNRIAVIQEGAFTNLTSLRR 427
              P+  +   L L  N +  +    + +   +L  ++L NN+I  ++EGAF    S++ 
Sbjct: 528 SHLPEYVTD--LRLNDNEVSVLEATGIFKKLPNLRKINLSNNKIKEVREGAFDGAASVQE 585

Query: 428 LYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNNNLLRSLP 487
           L L GN LE ++  +F GL  L+ L L  N+I  +   TF  L +++LL L +N + ++ 
Sbjct: 586 LMLTGNQLETVHGRVFRGLSGLKTLMLRSNLIGCVSNDTFAGLSSVRLLSLYDNRITTIT 645

Query: 488 DNIFGGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMGLKDWTEHA 547
              F  T L  L+                       I+L  NP++C C +  L  W    
Sbjct: 646 PGAF--TTLVSLST----------------------INLLSNPFNCNCHLAWLGKWLRKR 681

Query: 548 NSPVIINEVTCESP 561
              ++     C+ P
Sbjct: 682 R--IVSGNPRCQKP 693



 Score = 95.9 bits (237), Expect = 1e-19
 Identities = 72/249 (28%), Positives = 114/249 (45%), Gaps = 17/249 (6%)

Query: 335 PVPLTCPSSCVCTSQSSD-NGLNVNCQERKFTNISDLQPKPTSPKKLYLTGNYLQTVYKN 393
           P  + CP+ C C++ S D +GL +    R           P + ++L L  N +  + K 
Sbjct: 29  PPAVACPTKCTCSAASVDCHGLGLRAVPRGI---------PRNAERLDLDRNNITRITKM 79

Query: 394 DLLEYSSLDLLHLGNNRIAVIQEGAFTNLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLY 453
           D     +L +LHL +N+++VI+ GAF +L  L RL LN N L+VL   +F     L  L 
Sbjct: 80  DFAGLKNLRVLHLEDNQVSVIERGAFQDLKQLERLRLNKNKLQVLPELLFQSTPKLTRLD 139

Query: 454 LEYNVIKEIKPLTFDALINLQLLFLNNNLLRSLPDNIFGGTA-LTRLNLRNNHFSHLPVK 512
           L  N I+ I    F  + +++ L L+NN +  + D  F     L  L L NN+ S + V 
Sbjct: 140 LSENQIQGIPRKAFRGITDVKNLQLDNNHISCIEDGAFRALRDLEILTLNNNNISRILVT 199

Query: 513 GVLDQLPAFIQIDLQENPWDCTCDIMGLKDWTEHANSPVIINEVT-CESPAKHAG-EILK 570
              + +P    + L  N   C C +  L DW     +   + + T C +P    G  +  
Sbjct: 200 S-FNHMPKIRTLRLHSNHLYCDCHLAWLSDWLRQRRT---VGQFTLCMAPVHLRGFNVAD 255

Query: 571 FLGREAICP 579
              +E +CP
Sbjct: 256 VQKKEYVCP 264



 Score = 89.0 bits (219), Expect = 2e-17
 Identities = 101/436 (23%), Positives = 162/436 (37%), Gaps = 59/436 (13%)

Query: 29  CKIRCLCEEKENVLNINCENKGFTTVSLLQPPQYRIYQLFLNGNLLTRLYPNEFVNYSNA 88
           C   C C    N+  ++C  KG   +    P    I ++ L  N +  +    F  Y   
Sbjct: 280 CPSPCTCSN--NI--VDCRGKGLMEIPANLPEG--IVEIRLEQNSIKAIPAGAFTQYKKL 333

Query: 89  VTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLEILREDTFLGLESLEYLQADYNYISA 148
             + +  N + +I   AF GLK+L  L L  NK+  + +  F GL SL+ L  + N I+ 
Sbjct: 334 KRIDISKNQISDIAPDAFQGLKSLTSLVLYGNKITEIAKGLFDGLVSLQLLLLNANKINC 393

Query: 149 IEAGAFSKLNKLKVLILNDNLLLSLPSNVFRFVLLTHLDLRGNRLKVMPFAGVLEHIGGI 208
           +    F  L  L +L L DN L ++                          G+   +  I
Sbjct: 394 LRVNTFQDLQNLNLLSLYDNKLQTISK------------------------GLFAPLQSI 429

Query: 209 MEIQLEENPWNCTCDLLPLKAWLDTITVFVGEIVCETPFRLHGKDVTQLTRQDLCPRKSA 268
             + L +NP+ C C L  L  +L    +      C +P RL  K ++Q+  +    R S 
Sbjct: 430 QTLHLAQNPFVCDCHLKWLADYLQDNPIETSGARCSSPRRLANKRISQIKSKKF--RCSG 487

Query: 269 SDSSQRGSHADTHVQRLSPTMNPALNPTRAPKASRPPKMRNRPTPRVTVSKDRQSFGPIM 328
           S+  +    ++  +  +                  P K R   T    V    Q    I 
Sbjct: 488 SEDYRSRFSSECFMDLVC-----------------PEKCRCEGT---IVDCSNQKLVRIP 527

Query: 329 VYQTKSPVPLTCPSSCVCTSQSS------DNGLNVNCQERKFTNISD-LQPKPTSPKKLY 381
            +  +    L    + V   +++       N   +N    K   + +       S ++L 
Sbjct: 528 SHLPEYVTDLRLNDNEVSVLEATGIFKKLPNLRKINLSNNKIKEVREGAFDGAASVQELM 587

Query: 382 LTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFTNLTSLRRLYLNGNYLEVLYPS 441
           LTGN L+TV+       S L  L L +N I  +    F  L+S+R L L  N +  + P 
Sbjct: 588 LTGNQLETVHGRVFRGLSGLKTLMLRSNLIGCVSNDTFAGLSSVRLLSLYDNRITTITPG 647

Query: 442 MFDGLQSLQYLYLEYN 457
            F  L SL  + L  N
Sbjct: 648 AFTTLVSLSTINLLSN 663



 Score = 86.7 bits (213), Expect = 8e-17
 Identities = 98/409 (23%), Positives = 158/409 (38%), Gaps = 54/409 (13%)

Query: 28  ICKIRCLCEEKENVLNINCENKGFTTVSLLQPPQYRIYQLFLNGNLLTRLYPNE-FVNYS 86
           +C  +C CE       ++C N+    +     P+Y +  L LN N ++ L     F    
Sbjct: 504 VCPEKCRCEGTI----VDCSNQKLVRIPS-HLPEY-VTDLRLNDNEVSVLEATGIFKKLP 557

Query: 87  NAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLEILREDTFLGLESLEYLQADYNYI 146
           N   ++L NN ++E+R GAF G  +++ L L  N+LE +    F GL  L+ L    N I
Sbjct: 558 NLRKINLSNNKIKEVREGAFDGAASVQELMLTGNQLETVHGRVFRGLSGLKTLMLRSNLI 617

Query: 147 SAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRFVLLTHLDLRGNRLKVMPFAGVLEHIG 206
             +    F+ L+ +++L L DN + ++    F  ++                        
Sbjct: 618 GCVSNDTFAGLSSVRLLSLYDNRITTITPGAFTTLV------------------------ 653

Query: 207 GIMEIQLEENPWNCTCDLLPLKAWLDTITVFVGEIVCETPFRLHGKDVTQLTRQDLCPRK 266
            +  I L  NP+NC C L  L  WL    +  G   C+ PF L    +  +  QD     
Sbjct: 654 SLSTINLLSNPFNCNCHLAWLGKWLRKRRIVSGNPRCQKPFFLKEIPIQDVAIQDFTCDG 713

Query: 267 SASDSSQRGSHADTHVQRLSPTMNPALNPTRAPKASRPPKMRNRPTPRVTVSKDRQSFGP 326
           +   S Q           +   +  +    RA     P              KD      
Sbjct: 714 NEESSCQLSPRCPEQCTCMETVVRCSNKGLRALPRGMP--------------KDVTELYL 759

Query: 327 IMVYQTKSPVPLTCPSSCVCTSQSSDNGLNVNCQERKFTNISDLQPKPTSPKKLYLTGNY 386
              + T  P  L+     +     S+N +++      F+N+S L         L L+ N 
Sbjct: 760 EGNHLTAVPRELSALRH-LTLIDLSNNSISM-LTNYTFSNMSHL-------STLILSYNR 810

Query: 387 LQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFTNLTSLRRLYLNGNYL 435
           L+ +  +      SL +L L  N I+ + EG+F +LTSL  L L  N L
Sbjct: 811 LRCIPVHAFNGLRSLRVLTLHGNDISSVPEGSFNDLTSLSHLALGTNPL 859



 Score = 70.9 bits (172), Expect = 5e-12
 Identities = 85/349 (24%), Positives = 144/349 (41%), Gaps = 30/349 (8%)

Query: 139 LQADYNYISAIEA-GAFSKLNKLKVLILNDNLLLSLPSNVFRFVL-LTHLDLRGNRLKVM 196
           L+ + N +S +EA G F KL  L+ + L++N +  +    F     +  L L GN+L+ +
Sbjct: 537 LRLNDNEVSVLEATGIFKKLPNLRKINLSNNKIKEVREGAFDGAASVQELMLTGNQLETV 596

Query: 197 PFAGVLEHIGGIMEIQLEENPWNCTCDLLPLKAWLDTITVFVGEIVCETPFRLHGKDVTQ 256
               V   + G+  + L  N   C  +        DT   F G +       L+   +T 
Sbjct: 597 -HGRVFRGLSGLKTLMLRSNLIGCVSN--------DT---FAG-LSSVRLLSLYDNRITT 643

Query: 257 LTRQDLCPRKSASDSSQRGS--HADTHVQRLSPTMNPALNPTRAPKASRPPKMRNRPTPR 314
           +T        S S  +   +  + + H+  L   +      +  P+  +P  ++  P   
Sbjct: 644 ITPGAFTTLVSLSTINLLSNPFNCNCHLAWLGKWLRKRRIVSGNPRCQKPFFLKEIPIQD 703

Query: 315 VTVSKDRQSFGPIMVYQTKSPVPLTCPSSCVCTSQSSDNGLNVNCQERKFTNISDLQPKP 374
           V +    Q F      ++   +   CP  C C          V C  +    +    PK 
Sbjct: 704 VAI----QDFTCDGNEESSCQLSPRCPEQCTCMETV------VRCSNKGLRALPRGMPKD 753

Query: 375 TSPKKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFTNLTSLRRLYLNGNY 434
            +  +LYL GN+L T    +L     L L+ L NN I+++    F+N++ L  L L+ N 
Sbjct: 754 VT--ELYLEGNHL-TAVPRELSALRHLTLIDLSNNSISMLTNYTFSNMSHLSTLILSYNR 810

Query: 435 LEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNNNLL 483
           L  +    F+GL+SL+ L L  N I  +   +F+ L +L  L L  N L
Sbjct: 811 LRCIPVHAFNGLRSLRVLTLHGNDISSVPEGSFNDLTSLSHLALGTNPL 859



 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 53/218 (24%), Positives = 78/218 (35%), Gaps = 55/218 (25%)

Query: 29  CKIRCLCEEKENVLNINCENKGFTTVSLLQPPQYRIYQLFLNGNLLTRLYPNEFVNYSNA 88
           C  +C C E      + C NKG   +    P    + +L+L GN LT + P E       
Sbjct: 725 CPEQCTCMETV----VRCSNKGLRALPRGMPKD--VTELYLEGNHLTAV-PREL------ 771

Query: 89  VTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLEILREDTFLGLESLEYLQADYNYISA 148
                             S L+ L  + L+NN + +L   TF  +  L  L   YN +  
Sbjct: 772 ------------------SALRHLTLIDLSNNSISMLTNYTFSNMSHLSTLILSYNRLRC 813

Query: 149 IEAGAFSKLNKLKVLILNDNLLLSLPSNVFRFVLLTHLDLRGNRLKVMPFAGVLEHIGGI 208
           I   AF+ L  L+VL L+ N + S+P   F                          +  +
Sbjct: 814 IPVHAFNGLRSLRVLTLHGNDISSVPEGSFN------------------------DLTSL 849

Query: 209 MEIQLEENPWNCTCDLLPLKAWLDTITVFVGEIVCETP 246
             + L  NP +C C L  L  W+       G   C +P
Sbjct: 850 SHLALGTNPLHCDCSLRWLSEWVKAGYKEPGIARCSSP 887


>gi|194440719 chondroadherin-like [Homo sapiens]
          Length = 762

 Score =  125 bits (314), Expect = 2e-28
 Identities = 135/519 (26%), Positives = 196/519 (37%), Gaps = 106/519 (20%)

Query: 66  QLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLEIL 125
           +L L GN L  L P  F       TL+L +N L  +   AF GL  ++ L L++N L +L
Sbjct: 138 RLELEGNALEELRPGTFGALGALATLNLAHNALVYLPAMAFQGLLRVRWLRLSHNALSVL 197

Query: 126 REDTFLGLESLEYLQADYNYISAIEAGAFSK------------------------LNKLK 161
             +   GL +L  L   +N + A+     S+                        L  L+
Sbjct: 198 APEALAGLPALRRLSLHHNELQALPGPVLSQARGLARLELGHNPLTYAGEEDGLALPGLR 257

Query: 162 VLILNDNLLLSLPSNVFRFVLLTH-LDLRGNRLKVMPFAGVLEHIGGIMEIQLEENPWNC 220
            L+L+   L +L    F      H LDLRGN+L  +P    L+  G +  ++L+ NP  C
Sbjct: 258 ELLLDGGALQALGPRAFAHCPRLHTLDLRGNQLDTLP---PLQGPGQLRRLRLQGNPLWC 314

Query: 221 TCDLLPLKAWLDTITVFVGEIVCETPFRLHGKDVTQLTRQDL-CPRKSASDSSQRGSHAD 279
            C   PL  WL    V   +  C+ P RL G+ +  L   DL CP  +A +  +    A 
Sbjct: 315 GCQARPLLEWLARARV-RSDGACQGPRRLRGEALDALRPWDLRCPGDAAQEEEELEERA- 372

Query: 280 THVQRLSPTMNPALNPTRAPKASRPPKMRNRPTPRVTVSKDRQSFGPIMVYQTKSPVPLT 339
                ++    P   P R P   R                                    
Sbjct: 373 -----VAGPRAPPRGPPRGPGEER--------------------------------AVAP 395

Query: 340 CPSSCVCTSQ---SSDNGLNVNCQERKFTNISDLQPKPTSPKKLYLTGNYLQTVYKNDLL 396
           CP +CVC  +   SS  G  +    R F         P+  + L L  N+  +V +    
Sbjct: 396 CPRACVCVPESRHSSCEGCGLQAVPRGF---------PSDTQLLDLRRNHFPSVPRAAFP 446

Query: 397 EYSSLDLLHLGNNRIAVIQEGAFTNLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEY 456
               L  LHL +  IA ++ GA   L  L  LYL+ N L  L  +  +G   L YLYLE 
Sbjct: 447 GLGHLVSLHLQHCGIAELEAGALAGLGRLIYLYLSDNQLAGLSAAALEGAPRLGYLYLER 506

Query: 457 NVIKEIKPLTFDALINLQLLFLNNNLLRSLPDNIFGGT---------------------- 494
           N   ++      AL +L  L L +N +  L     G T                      
Sbjct: 507 NRFLQVPGAALRALPSLFSLHLQDNAVDRLAPGDLGRTRALRWVYLSGNRITEVSLGALG 566

Query: 495 ---ALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENP 530
               L +L+L  N    +P  G L+ LPA +++ L  NP
Sbjct: 567 PARELEKLHLDRNQLREVPT-GALEGLPALLELQLSGNP 604



 Score = 82.0 bits (201), Expect = 2e-15
 Identities = 59/194 (30%), Positives = 93/194 (47%), Gaps = 7/194 (3%)

Query: 64  IYQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLE 123
           ++ L L  N + RL P +         ++L  N + E+  GA    + L++LHL+ N+L 
Sbjct: 523 LFSLHLQDNAVDRLAPGDLGRTRALRWVYLSGNRITEVSLGALGPARELEKLHLDRNQLR 582

Query: 124 ILREDTFLGLESLEYLQADYNYISAIEAGAFSKLNK-LKVLILNDNLLLSLPSNVFRFV- 181
            +      GL +L  LQ   N + A+  GAF  + + L+ L LN + L  +    F  + 
Sbjct: 583 EVPTGALEGLPALLELQLSGNPLRALRDGAFQPVGRSLQHLFLNSSGLEQICPGAFSGLG 642

Query: 182 -LLTHLDLRGNRLKVMPFAGVLEHIGGIMEIQLEENPWNCTCDLLPLKAWLDTITVFVGE 240
             L  L L+ N+L+ +P    L  +  +  I L  NP++C C LLPL  WL  + + VG 
Sbjct: 643 PGLQSLHLQKNQLRALP---ALPSLSQLELIDLSSNPFHCDCQLLPLHRWLTGLNLRVG- 698

Query: 241 IVCETPFRLHGKDV 254
             C TP    G+ V
Sbjct: 699 ATCATPPNARGQRV 712



 Score = 80.5 bits (197), Expect = 6e-15
 Identities = 65/191 (34%), Positives = 92/191 (48%), Gaps = 8/191 (4%)

Query: 340 CPSSCVCTSQSSDNGLNVNCQERKFTNISDLQPKPTSPKKLYLTGNYLQTVYKNDLLEYS 399
           CP +C+C +       +V C+ +  T + D  P+ T  ++L L GN L+ +         
Sbjct: 33  CPQACICDNSRR----HVACRYQNLTEVPDAIPELT--QRLDLQGNLLKVIPAAAFQGVP 86

Query: 400 SLDLLHLGNNRIAVIQEGAFTNLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVI 459
            L  L L +  + ++ EGAF  L  L  L L  N+L  L     DGL SL+ L LE N +
Sbjct: 87  HLTHLDLRHCEVELVAEGAFRGLGRLLLLNLASNHLRELPQEALDGLGSLRRLELEGNAL 146

Query: 460 KEIKPLTFDALINLQLLFLNNNLLRSLPDNIFGGTALTR-LNLRNNHFSHLPVKGVLDQL 518
           +E++P TF AL  L  L L +N L  LP   F G    R L L +N  S L  +  L  L
Sbjct: 147 EELRPGTFGALGALATLNLAHNALVYLPAMAFQGLLRVRWLRLSHNALSVLAPE-ALAGL 205

Query: 519 PAFIQIDLQEN 529
           PA  ++ L  N
Sbjct: 206 PALRRLSLHHN 216



 Score = 66.2 bits (160), Expect = 1e-10
 Identities = 61/227 (26%), Positives = 95/227 (41%), Gaps = 30/227 (13%)

Query: 16  ILQTESRKTAKDICKIRCLCEEKENVLNINCENKGFTTVSLLQPPQYRIYQLFLNGNLLT 75
           +L   +R+ A   C   C+C+      ++ C  +  T V    P   +  +L L GNLL 
Sbjct: 20  LLLAPARQAAAQRCPQACICDNSRR--HVACRYQNLTEVPDAIPELTQ--RLDLQGNLLK 75

Query: 76  RLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLEILREDTFLGLES 135
            +    F    +   L L +  ++ +  GAF GL  L  L+L +N L  L ++   GL S
Sbjct: 76  VIPAAAFQGVPHLTHLDLRHCEVELVAEGAFRGLGRLLLLNLASNHLRELPQEALDGLGS 135

Query: 136 LEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVF------RFVLLTH---- 185
           L  L+ + N +  +  G F  L  L  L L  N L+ LP+  F      R++ L+H    
Sbjct: 136 LRRLELEGNALEELRPGTFGALGALATLNLAHNALVYLPAMAFQGLLRVRWLRLSHNALS 195

Query: 186 ---------------LDLRGNRLKVMPFAGVLEHIGGIMEIQLEENP 217
                          L L  N L+ +P   VL    G+  ++L  NP
Sbjct: 196 VLAPEALAGLPALRRLSLHHNELQALP-GPVLSQARGLARLELGHNP 241



 Score = 65.9 bits (159), Expect = 2e-10
 Identities = 63/230 (27%), Positives = 90/230 (39%), Gaps = 35/230 (15%)

Query: 380 LYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFTNLTSLRRLYLNGNYLEVLY 439
           LYL  N    V    L    SL  LHL +N +  +  G      +LR +YL+GN +  + 
Sbjct: 502 LYLERNRFLQVPGAALRALPSLFSLHLQDNAVDRLAPGDLGRTRALRWVYLSGNRITEVS 561

Query: 440 PSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNNNLLRSLPDNIFG------- 492
                  + L+ L+L+ N ++E+     + L  L  L L+ N LR+L D  F        
Sbjct: 562 LGALGPARELEKLHLDRNQLREVPTGALEGLPALLELQLSGNPLRALRDGAFQPVGRSLQ 621

Query: 493 --------------------GTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWD 532
                               G  L  L+L+ N    LP    L QL     IDL  NP+ 
Sbjct: 622 HLFLNSSGLEQICPGAFSGLGPGLQSLHLQKNQLRALPALPSLSQLEL---IDLSSNPFH 678

Query: 533 CTCDIMGLKDWTEHANSPVIINEVTCESPAKHAGEILKFLGREAICPDSP 582
           C C ++ L  W    N  V     TC +P    G+ +K     A+  D P
Sbjct: 679 CDCQLLPLHRWLTGLNLRV---GATCATPPNARGQRVK--AAAAVFEDCP 723



 Score = 62.0 bits (149), Expect = 2e-09
 Identities = 62/222 (27%), Positives = 93/222 (41%), Gaps = 31/222 (13%)

Query: 376 SPKKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFTNLTSLRRLYLNGNYL 435
           S ++L L GN L+ +         +L  L+L +N +  +   AF  L  +R L L+ N L
Sbjct: 135 SLRRLELEGNALEELRPGTFGALGALATLNLAHNALVYLPAMAFQGLLRVRWLRLSHNAL 194

Query: 436 EVLYPSMFDGLQSLQYLYLEYNVIKEI------------------KPLTFD------ALI 471
            VL P    GL +L+ L L +N ++ +                   PLT+       AL 
Sbjct: 195 SVLAPEALAGLPALRRLSLHHNELQALPGPVLSQARGLARLELGHNPLTYAGEEDGLALP 254

Query: 472 NLQLLFLNNNLLRSLPDNIFGGTA-LTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENP 530
            L+ L L+   L++L    F     L  L+LR N    LP      QL    ++ LQ NP
Sbjct: 255 GLRELLLDGGALQALGPRAFAHCPRLHTLDLRGNQLDTLPPLQGPGQLR---RLRLQGNP 311

Query: 531 WDCTCDIMGLKDWTEHANSPVIINEVTCESPAKHAGEILKFL 572
             C C    L +W   A    + ++  C+ P +  GE L  L
Sbjct: 312 LWCGCQARPLLEWLARAR---VRSDGACQGPRRLRGEALDAL 350


>gi|13194201 reticulon 4 receptor precursor [Homo sapiens]
          Length = 473

 Score =  105 bits (263), Expect = 1e-22
 Identities = 75/214 (35%), Positives = 107/214 (50%), Gaps = 10/214 (4%)

Query: 51  FTTVSLLQPPQYRIYQLFLNGNLLTR-LYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGL 109
           FT ++LL+       QL L+ N   R + P  F       TLHL   GLQE+  G F GL
Sbjct: 101 FTGLALLE-------QLDLSDNAQLRSVDPATFHGLGRLHTLHLDRCGLQELGPGLFRGL 153

Query: 110 KTLKRLHLNNNKLEILREDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNL 169
             L+ L+L +N L+ L +DTF  L +L +L    N IS++   AF  L+ L  L+L+ N 
Sbjct: 154 AALQYLYLQDNALQALPDDTFRDLGNLTHLFLHGNRISSVPERAFRGLHSLDRLLLHQNR 213

Query: 170 LLSLPSNVFRFV-LLTHLDLRGNRLKVMPFAGVLEHIGGIMEIQLEENPWNCTCDLLPLK 228
           +  +  + FR +  L  L L  N L  +P    L  +  +  ++L +NPW C C   PL 
Sbjct: 214 VAHVHPHAFRDLGRLMTLYLFANNLSALP-TEALAPLRALQYLRLNDNPWVCDCRARPLW 272

Query: 229 AWLDTITVFVGEIVCETPFRLHGKDVTQLTRQDL 262
           AWL        E+ C  P RL G+D+ +L   DL
Sbjct: 273 AWLQKFRGSSSEVPCSLPQRLAGRDLKRLAANDL 306



 Score = 89.0 bits (219), Expect = 2e-17
 Identities = 80/287 (27%), Positives = 119/287 (41%), Gaps = 58/287 (20%)

Query: 336 VPLTCPSSCVCTSQSSDNGLNVNCQERKFTNISDLQPKPTSPKKLYLTGNYLQTVYKNDL 395
           V   CP +CVC ++     +  +C ++    +      P + ++++L GN +  V     
Sbjct: 23  VAAPCPGACVCYNEPK---VTTSCPQQGLQAVP--VGIPAASQRIFLHGNRISHVPAASF 77

Query: 396 LEYSSLDLLHLGNNRIAVIQEGAFTNLTSLRRLYLNGNY--------------------- 434
               +L +L L +N +A I   AFT L  L +L L+ N                      
Sbjct: 78  RACRNLTILWLHSNVLARIDAAAFTGLALLEQLDLSDNAQLRSVDPATFHGLGRLHTLHL 137

Query: 435 ----LEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNNNLLRSLPDNI 490
               L+ L P +F GL +LQYLYL+ N ++ +   TF  L NL  LFL+ N + S+P+  
Sbjct: 138 DRCGLQELGPGLFRGLAALQYLYLQDNALQALPDDTFRDLGNLTHLFLHGNRISSVPERA 197

Query: 491 FGGT-ALTRLNLRNNHFSH------------------------LPVKGVLDQLPAFIQID 525
           F G  +L RL L  N  +H                        LP +  L  L A   + 
Sbjct: 198 FRGLHSLDRLLLHQNRVAHVHPHAFRDLGRLMTLYLFANNLSALPTE-ALAPLRALQYLR 256

Query: 526 LQENPWDCTCDIMGLKDWTEHANSPVIINEVTCESPAKHAGEILKFL 572
           L +NPW C C    L  W +        +EV C  P + AG  LK L
Sbjct: 257 LNDNPWVCDCRARPLWAWLQKFRGS--SSEVPCSLPQRLAGRDLKRL 301


>gi|205277468 leucine rich repeat containing 15 isoform a [Homo
           sapiens]
          Length = 587

 Score =  105 bits (262), Expect = 2e-22
 Identities = 72/238 (30%), Positives = 116/238 (48%), Gaps = 43/238 (18%)

Query: 54  VSLLQPP----QYRIYQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGL 109
           + LL P      + + +L+L+ N +++L P+ F+       L L  N L+E+  G F  +
Sbjct: 239 IGLLSPGLFHNNHNLQRLYLSNNHISQLPPSIFMQLPQLNRLTLFGNSLKELSLGIFGPM 298

Query: 110 KTLKRLHLNNNKLEILREDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNL 169
             L+ L L +N +  L ++ F  L  L+ L    N IS I  GAF+ L +L+ L L+ N 
Sbjct: 299 PNLRELWLYDNHISSLPDNVFSNLRQLQVLILSRNQISFISPGAFNGLTELRELSLHTNA 358

Query: 170 LLSLPSNVFRFVL-LTHLDLRGNRLKVMP---FA--------------------GVLEHI 205
           L  L  NVFR +  L ++ L+ NRL+ +P   FA                    G+ +H+
Sbjct: 359 LQDLDGNVFRMLANLQNISLQNNRLRQLPGNIFANVNGLMAIQLQNNQLENLPLGIFDHL 418

Query: 206 GGIMEIQLEENPWNCTCDLLPLKAWL---------DTITVFVGEIVCETPFRLHGKDV 254
           G + E++L +NPW C  D+LPL+ WL         DT+       VC +P  + G+ +
Sbjct: 419 GKLCELRLYDNPWRCDSDILPLRNWLLLNQPRLGTDTVP------VCFSPANVRGQSL 470



 Score =  102 bits (253), Expect = 2e-21
 Identities = 67/204 (32%), Positives = 102/204 (50%), Gaps = 5/204 (2%)

Query: 379 KLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFTNLTSLRRLYLNGNYLEVL 438
           +L L GN L+ +         +L  L L +N I+ + +  F+NL  L+ L L+ N +  +
Sbjct: 279 RLTLFGNSLKELSLGIFGPMPNLRELWLYDNHISSLPDNVFSNLRQLQVLILSRNQISFI 338

Query: 439 YPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNNNLLRSLPDNIFGG-TALT 497
            P  F+GL  L+ L L  N ++++    F  L NLQ + L NN LR LP NIF     L 
Sbjct: 339 SPGAFNGLTELRELSLHTNALQDLDGNVFRMLANLQNISLQNNRLRQLPGNIFANVNGLM 398

Query: 498 RLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMGLKDWTEHANSPVIINEV- 556
            + L+NN   +LP+ G+ D L    ++ L +NPW C  DI+ L++W    N P +  +  
Sbjct: 399 AIQLQNNQLENLPL-GIFDHLGKLCELRLYDNPWRCDSDILPLRNWL-LLNQPRLGTDTV 456

Query: 557 -TCESPAKHAGEILKFLGREAICP 579
             C SPA   G+ L  +      P
Sbjct: 457 PVCFSPANVRGQSLIIINVNVAVP 480



 Score = 88.6 bits (218), Expect = 2e-17
 Identities = 58/171 (33%), Positives = 84/171 (49%), Gaps = 8/171 (4%)

Query: 340 CPSSCVCTSQSSDNGLNVNCQERKFTNISDLQPKPTSPKKLYLTGNYLQTVYKNDLLEYS 399
           CPS C C+  S      V C   +   +    P P +   L +   ++  + ++  L  S
Sbjct: 31  CPSECTCSRASQ-----VECTGARIVAVPT--PLPWNAMSLQILNTHITELNESPFLNIS 83

Query: 400 SLDLLHLGNNRIAVIQEGAFTNLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVI 459
           +L  L +  N ++ I  GAF NL SLR L L  N L+VL   +F GL SL+ L L  N +
Sbjct: 84  ALIALRIEKNELSRITPGAFRNLGSLRYLSLANNKLQVLPIGLFQGLDSLESLLLSSNQL 143

Query: 460 KEIKPLTFDALINLQLLFLNNNLLRSLPDNIFGG-TALTRLNLRNNHFSHL 509
            +I+P  F    NL+ L L+ N L  +PD  F     LT+LNL  N  +H+
Sbjct: 144 LQIQPAHFSQCSNLKELQLHGNHLEYIPDGAFDHLVGLTKLNLGKNSLTHI 194



 Score = 83.6 bits (205), Expect = 7e-16
 Identities = 62/189 (32%), Positives = 89/189 (47%), Gaps = 7/189 (3%)

Query: 29  CKIRCLCEEKENVLNINCENKGFTTVSLLQPPQYRIYQLFLNGNLLTRLYPNEFVNYSNA 88
           C   C C     V     E  G   V++  P  +    L +    +T L  + F+N S  
Sbjct: 31  CPSECTCSRASQV-----ECTGARIVAVPTPLPWNAMSLQILNTHITELNESPFLNISAL 85

Query: 89  VTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLEILREDTFLGLESLEYLQADYNYISA 148
           + L +  N L  I  GAF  L +L+ L L NNKL++L    F GL+SLE L    N +  
Sbjct: 86  IALRIEKNELSRITPGAFRNLGSLRYLSLANNKLQVLPIGLFQGLDSLESLLLSSNQLLQ 145

Query: 149 IEAGAFSKLNKLKVLILNDNLLLSLPSNVF-RFVLLTHLDLRGNRLKVMPFAGVLEHIGG 207
           I+   FS+ + LK L L+ N L  +P   F   V LT L+L  N L  +    V +H+G 
Sbjct: 146 IQPAHFSQCSNLKELQLHGNHLEYIPDGAFDHLVGLTKLNLGKNSLTHIS-PRVFQHLGN 204

Query: 208 IMEIQLEEN 216
           +  ++L EN
Sbjct: 205 LQVLRLYEN 213



 Score = 68.2 bits (165), Expect = 3e-11
 Identities = 57/179 (31%), Positives = 76/179 (42%), Gaps = 26/179 (14%)

Query: 376 SPKKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFTNLTSLRRLYLNGNYL 435
           S + L L  N LQ +         SL+ L L +N++  IQ   F+  ++L+ L L+GN+L
Sbjct: 108 SLRYLSLANNKLQVLPIGLFQGLDSLESLLLSSNQLLQIQPAHFSQCSNLKELQLHGNHL 167

Query: 436 EVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNNNLLRSLPDNIFGGTA 495
           E +    FD L  L  L L  N +  I P  F  L NLQ+L L  N L  +P   F G  
Sbjct: 168 EYIPDGAFDHLVGLTKLNLGKNSLTHISPRVFQHLGNLQVLRLYENRLTDIPMGTFDGLV 227

Query: 496 -------------------------LTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQEN 529
                                    L RL L NNH S LP   +  QLP   ++ L  N
Sbjct: 228 NLQELALQQNQIGLLSPGLFHNNHNLQRLYLSNNHISQLP-PSIFMQLPQLNRLTLFGN 285



 Score = 65.5 bits (158), Expect = 2e-10
 Identities = 48/133 (36%), Positives = 62/133 (46%), Gaps = 1/133 (0%)

Query: 379 KLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFTNLTSLRRLYLNGNYLEVL 438
           KL L  N L  +         +L +L L  NR+  I  G F  L +L+ L L  N + +L
Sbjct: 183 KLNLGKNSLTHISPRVFQHLGNLQVLRLYENRLTDIPMGTFDGLVNLQELALQQNQIGLL 242

Query: 439 YPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNNNLLRSLPDNIFGGTA-LT 497
            P +F    +LQ LYL  N I ++ P  F  L  L  L L  N L+ L   IFG    L 
Sbjct: 243 SPGLFHNNHNLQRLYLSNNHISQLPPSIFMQLPQLNRLTLFGNSLKELSLGIFGPMPNLR 302

Query: 498 RLNLRNNHFSHLP 510
            L L +NH S LP
Sbjct: 303 ELWLYDNHISSLP 315



 Score = 62.4 bits (150), Expect = 2e-09
 Identities = 49/165 (29%), Positives = 77/165 (46%), Gaps = 6/165 (3%)

Query: 57  LQPPQY----RIYQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTL 112
           +QP  +     + +L L+GN L  +    F +      L+LG N L  I    F  L  L
Sbjct: 146 IQPAHFSQCSNLKELQLHGNHLEYIPDGAFDHLVGLTKLNLGKNSLTHISPRVFQHLGNL 205

Query: 113 KRLHLNNNKLEILREDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLS 172
           + L L  N+L  +   TF GL +L+ L    N I  +  G F   + L+ L L++N +  
Sbjct: 206 QVLRLYENRLTDIPMGTFDGLVNLQELALQQNQIGLLSPGLFHNNHNLQRLYLSNNHISQ 265

Query: 173 LPSNVF-RFVLLTHLDLRGNRLKVMPFAGVLEHIGGIMEIQLEEN 216
           LP ++F +   L  L L GN LK +   G+   +  + E+ L +N
Sbjct: 266 LPPSIFMQLPQLNRLTLFGNSLKELSL-GIFGPMPNLRELWLYDN 309



 Score = 36.6 bits (83), Expect = 0.10
 Identities = 36/121 (29%), Positives = 53/121 (43%), Gaps = 3/121 (2%)

Query: 375 TSPKKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFTNLTSLRRLYLNGNY 434
           T  ++L L  N LQ +  N     ++L  + L NNR+  +    F N+  L  + L  N 
Sbjct: 347 TELRELSLHTNALQDLDGNVFRMLANLQNISLQNNRLRQLPGNIFANVNGLMAIQLQNNQ 406

Query: 435 LEVLYPSMFDGLQSLQYLYLEYNVIK---EIKPLTFDALINLQLLFLNNNLLRSLPDNIF 491
           LE L   +FD L  L  L L  N  +   +I PL    L+N   L  +   +   P N+ 
Sbjct: 407 LENLPLGIFDHLGKLCELRLYDNPWRCDSDILPLRNWLLLNQPRLGTDTVPVCFSPANVR 466

Query: 492 G 492
           G
Sbjct: 467 G 467


>gi|18677767 leucine rich repeat containing 15 isoform b [Homo
           sapiens]
          Length = 581

 Score =  105 bits (262), Expect = 2e-22
 Identities = 72/238 (30%), Positives = 116/238 (48%), Gaps = 43/238 (18%)

Query: 54  VSLLQPP----QYRIYQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGL 109
           + LL P      + + +L+L+ N +++L P+ F+       L L  N L+E+  G F  +
Sbjct: 233 IGLLSPGLFHNNHNLQRLYLSNNHISQLPPSIFMQLPQLNRLTLFGNSLKELSLGIFGPM 292

Query: 110 KTLKRLHLNNNKLEILREDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNL 169
             L+ L L +N +  L ++ F  L  L+ L    N IS I  GAF+ L +L+ L L+ N 
Sbjct: 293 PNLRELWLYDNHISSLPDNVFSNLRQLQVLILSRNQISFISPGAFNGLTELRELSLHTNA 352

Query: 170 LLSLPSNVFRFVL-LTHLDLRGNRLKVMP---FA--------------------GVLEHI 205
           L  L  NVFR +  L ++ L+ NRL+ +P   FA                    G+ +H+
Sbjct: 353 LQDLDGNVFRMLANLQNISLQNNRLRQLPGNIFANVNGLMAIQLQNNQLENLPLGIFDHL 412

Query: 206 GGIMEIQLEENPWNCTCDLLPLKAWL---------DTITVFVGEIVCETPFRLHGKDV 254
           G + E++L +NPW C  D+LPL+ WL         DT+       VC +P  + G+ +
Sbjct: 413 GKLCELRLYDNPWRCDSDILPLRNWLLLNQPRLGTDTVP------VCFSPANVRGQSL 464



 Score =  102 bits (253), Expect = 2e-21
 Identities = 67/204 (32%), Positives = 102/204 (50%), Gaps = 5/204 (2%)

Query: 379 KLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFTNLTSLRRLYLNGNYLEVL 438
           +L L GN L+ +         +L  L L +N I+ + +  F+NL  L+ L L+ N +  +
Sbjct: 273 RLTLFGNSLKELSLGIFGPMPNLRELWLYDNHISSLPDNVFSNLRQLQVLILSRNQISFI 332

Query: 439 YPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNNNLLRSLPDNIFGG-TALT 497
            P  F+GL  L+ L L  N ++++    F  L NLQ + L NN LR LP NIF     L 
Sbjct: 333 SPGAFNGLTELRELSLHTNALQDLDGNVFRMLANLQNISLQNNRLRQLPGNIFANVNGLM 392

Query: 498 RLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMGLKDWTEHANSPVIINEV- 556
            + L+NN   +LP+ G+ D L    ++ L +NPW C  DI+ L++W    N P +  +  
Sbjct: 393 AIQLQNNQLENLPL-GIFDHLGKLCELRLYDNPWRCDSDILPLRNWL-LLNQPRLGTDTV 450

Query: 557 -TCESPAKHAGEILKFLGREAICP 579
             C SPA   G+ L  +      P
Sbjct: 451 PVCFSPANVRGQSLIIINVNVAVP 474



 Score = 88.6 bits (218), Expect = 2e-17
 Identities = 58/171 (33%), Positives = 84/171 (49%), Gaps = 8/171 (4%)

Query: 340 CPSSCVCTSQSSDNGLNVNCQERKFTNISDLQPKPTSPKKLYLTGNYLQTVYKNDLLEYS 399
           CPS C C+  S      V C   +   +    P P +   L +   ++  + ++  L  S
Sbjct: 25  CPSECTCSRASQ-----VECTGARIVAVPT--PLPWNAMSLQILNTHITELNESPFLNIS 77

Query: 400 SLDLLHLGNNRIAVIQEGAFTNLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVI 459
           +L  L +  N ++ I  GAF NL SLR L L  N L+VL   +F GL SL+ L L  N +
Sbjct: 78  ALIALRIEKNELSRITPGAFRNLGSLRYLSLANNKLQVLPIGLFQGLDSLESLLLSSNQL 137

Query: 460 KEIKPLTFDALINLQLLFLNNNLLRSLPDNIFGG-TALTRLNLRNNHFSHL 509
            +I+P  F    NL+ L L+ N L  +PD  F     LT+LNL  N  +H+
Sbjct: 138 LQIQPAHFSQCSNLKELQLHGNHLEYIPDGAFDHLVGLTKLNLGKNSLTHI 188



 Score = 83.6 bits (205), Expect = 7e-16
 Identities = 62/189 (32%), Positives = 89/189 (47%), Gaps = 7/189 (3%)

Query: 29  CKIRCLCEEKENVLNINCENKGFTTVSLLQPPQYRIYQLFLNGNLLTRLYPNEFVNYSNA 88
           C   C C     V     E  G   V++  P  +    L +    +T L  + F+N S  
Sbjct: 25  CPSECTCSRASQV-----ECTGARIVAVPTPLPWNAMSLQILNTHITELNESPFLNISAL 79

Query: 89  VTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLEILREDTFLGLESLEYLQADYNYISA 148
           + L +  N L  I  GAF  L +L+ L L NNKL++L    F GL+SLE L    N +  
Sbjct: 80  IALRIEKNELSRITPGAFRNLGSLRYLSLANNKLQVLPIGLFQGLDSLESLLLSSNQLLQ 139

Query: 149 IEAGAFSKLNKLKVLILNDNLLLSLPSNVF-RFVLLTHLDLRGNRLKVMPFAGVLEHIGG 207
           I+   FS+ + LK L L+ N L  +P   F   V LT L+L  N L  +    V +H+G 
Sbjct: 140 IQPAHFSQCSNLKELQLHGNHLEYIPDGAFDHLVGLTKLNLGKNSLTHIS-PRVFQHLGN 198

Query: 208 IMEIQLEEN 216
           +  ++L EN
Sbjct: 199 LQVLRLYEN 207



 Score = 68.2 bits (165), Expect = 3e-11
 Identities = 57/179 (31%), Positives = 76/179 (42%), Gaps = 26/179 (14%)

Query: 376 SPKKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFTNLTSLRRLYLNGNYL 435
           S + L L  N LQ +         SL+ L L +N++  IQ   F+  ++L+ L L+GN+L
Sbjct: 102 SLRYLSLANNKLQVLPIGLFQGLDSLESLLLSSNQLLQIQPAHFSQCSNLKELQLHGNHL 161

Query: 436 EVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNNNLLRSLPDNIFGGTA 495
           E +    FD L  L  L L  N +  I P  F  L NLQ+L L  N L  +P   F G  
Sbjct: 162 EYIPDGAFDHLVGLTKLNLGKNSLTHISPRVFQHLGNLQVLRLYENRLTDIPMGTFDGLV 221

Query: 496 -------------------------LTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQEN 529
                                    L RL L NNH S LP   +  QLP   ++ L  N
Sbjct: 222 NLQELALQQNQIGLLSPGLFHNNHNLQRLYLSNNHISQLP-PSIFMQLPQLNRLTLFGN 279



 Score = 65.5 bits (158), Expect = 2e-10
 Identities = 48/133 (36%), Positives = 62/133 (46%), Gaps = 1/133 (0%)

Query: 379 KLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFTNLTSLRRLYLNGNYLEVL 438
           KL L  N L  +         +L +L L  NR+  I  G F  L +L+ L L  N + +L
Sbjct: 177 KLNLGKNSLTHISPRVFQHLGNLQVLRLYENRLTDIPMGTFDGLVNLQELALQQNQIGLL 236

Query: 439 YPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNNNLLRSLPDNIFGGTA-LT 497
            P +F    +LQ LYL  N I ++ P  F  L  L  L L  N L+ L   IFG    L 
Sbjct: 237 SPGLFHNNHNLQRLYLSNNHISQLPPSIFMQLPQLNRLTLFGNSLKELSLGIFGPMPNLR 296

Query: 498 RLNLRNNHFSHLP 510
            L L +NH S LP
Sbjct: 297 ELWLYDNHISSLP 309



 Score = 62.4 bits (150), Expect = 2e-09
 Identities = 49/165 (29%), Positives = 77/165 (46%), Gaps = 6/165 (3%)

Query: 57  LQPPQY----RIYQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTL 112
           +QP  +     + +L L+GN L  +    F +      L+LG N L  I    F  L  L
Sbjct: 140 IQPAHFSQCSNLKELQLHGNHLEYIPDGAFDHLVGLTKLNLGKNSLTHISPRVFQHLGNL 199

Query: 113 KRLHLNNNKLEILREDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLS 172
           + L L  N+L  +   TF GL +L+ L    N I  +  G F   + L+ L L++N +  
Sbjct: 200 QVLRLYENRLTDIPMGTFDGLVNLQELALQQNQIGLLSPGLFHNNHNLQRLYLSNNHISQ 259

Query: 173 LPSNVF-RFVLLTHLDLRGNRLKVMPFAGVLEHIGGIMEIQLEEN 216
           LP ++F +   L  L L GN LK +   G+   +  + E+ L +N
Sbjct: 260 LPPSIFMQLPQLNRLTLFGNSLKELSL-GIFGPMPNLRELWLYDN 303



 Score = 36.6 bits (83), Expect = 0.10
 Identities = 36/121 (29%), Positives = 53/121 (43%), Gaps = 3/121 (2%)

Query: 375 TSPKKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFTNLTSLRRLYLNGNY 434
           T  ++L L  N LQ +  N     ++L  + L NNR+  +    F N+  L  + L  N 
Sbjct: 341 TELRELSLHTNALQDLDGNVFRMLANLQNISLQNNRLRQLPGNIFANVNGLMAIQLQNNQ 400

Query: 435 LEVLYPSMFDGLQSLQYLYLEYNVIK---EIKPLTFDALINLQLLFLNNNLLRSLPDNIF 491
           LE L   +FD L  L  L L  N  +   +I PL    L+N   L  +   +   P N+ 
Sbjct: 401 LENLPLGIFDHLGKLCELRLYDNPWRCDSDILPLRNWLLLNQPRLGTDTVPVCFSPANVR 460

Query: 492 G 492
           G
Sbjct: 461 G 461


>gi|30425563 reticulon 4 receptor-like 2 [Homo sapiens]
          Length = 420

 Score =  100 bits (250), Expect = 4e-21
 Identities = 90/321 (28%), Positives = 133/321 (41%), Gaps = 59/321 (18%)

Query: 29  CKIRCLCEEKENVLNINCENKGFTTVSLLQPPQYRIYQLFLNGNLLTRLYPNEFVNYSNA 88
           C + C C        ++C+   F++V L  PP  +  +LFL  NL+  L P  F   SN 
Sbjct: 31  CPMLCTCYSSPPT--VSCQANNFSSVPLSLPPSTQ--RLFLQNNLIRTLRPGTFG--SNL 84

Query: 89  VTLHLGNNGLQEIRTGAF-------------------------SGLKTLKRLHLNNNKLE 123
           +TL L +N L  I  G F                          GL+ L+ LHL   +L 
Sbjct: 85  LTLWLFSNNLSTIYPGTFRHLQALEELDLGDNRHLRSLEPDTFQGLERLQSLHLYRCQLS 144

Query: 124 ILREDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRFV-L 182
            L  + F GL SL+YL    N +  ++   F+ L  L  L L+ N L  L  +VFR +  
Sbjct: 145 SLPGNIFRGLVSLQYLYLQENSLLHLQDDLFADLANLSHLFLHGNRLRLLTEHVFRGLGS 204

Query: 183 LTHLDLRGNRLKVM---PFAGV--------------------LEHIGGIMEIQLEENPWN 219
           L  L L GNRL+ +    F G+                    L  +  +  ++L  NPW 
Sbjct: 205 LDRLLLHGNRLQGVHRAAFRGLSRLTILYLFNNSLASLPGEALADLPSLEFLRLNANPWA 264

Query: 220 CTCDLLPLKAWLDTITVFVGEIVCETPFRLHGKDVTQLTRQDL--CPRKSAS--DSSQRG 275
           C C   PL AW     V   ++ C TP    G+D+  L   D   CP  + +   S  RG
Sbjct: 265 CDCRARPLWAWFQRARVSSSDVTCATPPERQGRDLRALREADFQACPPAAPTRPGSRARG 324

Query: 276 SHADTHVQRLSPTMNPALNPT 296
           + +  H+  ++    P  +P+
Sbjct: 325 NSSSNHLYGVAEAGAPPADPS 345



 Score =  100 bits (248), Expect = 7e-21
 Identities = 88/299 (29%), Positives = 127/299 (42%), Gaps = 57/299 (19%)

Query: 339 TCPSSCVCTSQSSDNGLNVNCQERKFTNISDLQPKPTSPK-------------------- 378
           +CP  C C S        V+CQ   F+++    P  T                       
Sbjct: 30  SCPMLCTCYSSPP----TVSCQANNFSSVPLSLPPSTQRLFLQNNLIRTLRPGTFGSNLL 85

Query: 379 KLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNR-IAVIQEGAFTNLTSLRRLYLNGNYLEV 437
            L+L  N L T+Y        +L+ L LG+NR +  ++   F  L  L+ L+L    L  
Sbjct: 86  TLWLFSNNLSTIYPGTFRHLQALEELDLGDNRHLRSLEPDTFQGLERLQSLHLYRCQLSS 145

Query: 438 LYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNNNLLRSLPDNIFGG---- 493
           L  ++F GL SLQYLYL+ N +  ++   F  L NL  LFL+ N LR L +++F G    
Sbjct: 146 LPGNIFRGLVSLQYLYLQENSLLHLQDDLFADLANLSHLFLHGNRLRLLTEHVFRGLGSL 205

Query: 494 ---------------------TALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWD 532
                                + LT L L NN  + LP + + D LP+   + L  NPW 
Sbjct: 206 DRLLLHGNRLQGVHRAAFRGLSRLTILYLFNNSLASLPGEALAD-LPSLEFLRLNANPWA 264

Query: 533 CTCDIMGLKDWTEHANSPVIINEVTCESPAKHAGEILKFLGREA---ICPDSPNLSDGT 588
           C C    L  W + A   V  ++VTC +P +  G  L+ L REA    CP +     G+
Sbjct: 265 CDCRARPLWAWFQRAR--VSSSDVTCATPPERQGRDLRAL-READFQACPPAAPTRPGS 320


>gi|198041768 synleurin [Homo sapiens]
          Length = 622

 Score = 99.4 bits (246), Expect = 1e-20
 Identities = 67/232 (28%), Positives = 112/232 (48%), Gaps = 30/232 (12%)

Query: 380 LYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFTNLTSLRRLYLNGNYLEVLY 439
           L L+ N +  + ++      +L  L+LG+N +  +   AF  L SLRRL L+ N +E + 
Sbjct: 185 LDLSNNNILRISESGFQHLENLACLYLGSNNLTKVPSNAFEVLKSLRRLSLSHNPIEAIQ 244

Query: 440 PSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNNNLLRSLPDNIFG------- 492
           P  F GL +L+YL L+ + I+ +    F  + NL+ L L++N L +L  + F        
Sbjct: 245 PFAFKGLANLEYLLLKNSRIRNVTRDGFSGINNLKHLILSHNDLENLNSDTFSLLKNLIY 304

Query: 493 -------------------GTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDC 533
                              G +L  LNL  N+ + L  + VL  L + I +    NPW+C
Sbjct: 305 LKLDRNRIISIDNDTFENMGASLKILNLSFNNLTALHPR-VLKPLSSLIHLQANSNPWEC 363

Query: 534 TCDIMGLKDWTEHANSPVIINEVTCESPAKHAGEILKFLGREAICPDSPNLS 585
            C ++GL+DW   A+S + +N + C++P    G  L+++        S N+S
Sbjct: 364 NCKLLGLRDWL--ASSAITLN-IYCQNPPSMRGRALRYINITNCVTSSINVS 412



 Score = 98.2 bits (243), Expect = 3e-20
 Identities = 66/211 (31%), Positives = 107/211 (50%), Gaps = 26/211 (12%)

Query: 67  LFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLEILR 126
           L L+ N + R+  + F +  N   L+LG+N L ++ + AF  LK+L+RL L++N +E ++
Sbjct: 185 LDLSNNNILRISESGFQHLENLACLYLGSNNLTKVPSNAFEVLKSLRRLSLSHNPIEAIQ 244

Query: 127 EDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRFVL-LTH 185
              F GL +LEYL    + I  +    FS +N LK LIL+ N L +L S+ F  +  L +
Sbjct: 245 PFAFKGLANLEYLLLKNSRIRNVTRDGFSGINNLKHLILSHNDLENLNSDTFSLLKNLIY 304

Query: 186 LDLRGNR---------------LKVMPFA---------GVLEHIGGIMEIQLEENPWNCT 221
           L L  NR               LK++  +          VL+ +  ++ +Q   NPW C 
Sbjct: 305 LKLDRNRIISIDNDTFENMGASLKILNLSFNNLTALHPRVLKPLSSLIHLQANSNPWECN 364

Query: 222 CDLLPLKAWLDTITVFVGEIVCETPFRLHGK 252
           C LL L+ WL +  + +  I C+ P  + G+
Sbjct: 365 CKLLGLRDWLASSAITL-NIYCQNPPSMRGR 394



 Score = 87.8 bits (216), Expect = 4e-17
 Identities = 63/180 (35%), Positives = 93/180 (51%), Gaps = 14/180 (7%)

Query: 338 LTCPSSC-VCTSQSSDNGLNVNCQERKFTNISDLQPK--PTSPKKLYLTGNYLQTVYKND 394
           L C S C +CT      G  +NC+    ++I    PK  P S   LYLTGN +  + +++
Sbjct: 30  LGCSSVCQLCT------GRQINCRNLGLSSI----PKNFPESTVFLYLTGNNISYINESE 79

Query: 395 LLEYSSLDLLHLGNNRIAVIQEGAFTNLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYL 454
           L    SL  L+L N+ I  +   AF  L  L  L+LN N+++ L P +F GL +L+ LYL
Sbjct: 80  LTGLHSLVALYLDNSNILYVYPKAFVQLRHLYFLFLNNNFIKRLDPGIFKGLLNLRNLYL 139

Query: 455 EYNVIKEIKPLTFDALINLQLLFLNNNLLRSLPDNIF-GGTALTRLNLRNNHFSHLPVKG 513
           +YN +  +    F+ L+++Q L L  N L  L    F G  AL  L+L NN+   +   G
Sbjct: 140 QYNQVSFVPRGVFNDLVSVQYLNLQRNRLTVLGSGTFVGMVALRILDLSNNNILRISESG 199



 Score = 74.3 bits (181), Expect = 4e-13
 Identities = 48/138 (34%), Positives = 68/138 (49%), Gaps = 2/138 (1%)

Query: 64  IYQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLE 123
           +Y LFLN N + RL P  F    N   L+L  N +  +  G F+ L +++ L+L  N+L 
Sbjct: 110 LYFLFLNNNFIKRLDPGIFKGLLNLRNLYLQYNQVSFVPRGVFNDLVSVQYLNLQRNRLT 169

Query: 124 ILREDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRFV-L 182
           +L   TF+G+ +L  L    N I  I    F  L  L  L L  N L  +PSN F  +  
Sbjct: 170 VLGSGTFVGMVALRILDLSNNNILRISESGFQHLENLACLYLGSNNLTKVPSNAFEVLKS 229

Query: 183 LTHLDLRGNRLK-VMPFA 199
           L  L L  N ++ + PFA
Sbjct: 230 LRRLSLSHNPIEAIQPFA 247



 Score = 68.6 bits (166), Expect = 2e-11
 Identities = 53/174 (30%), Positives = 85/174 (48%), Gaps = 4/174 (2%)

Query: 44  INCENKGFTTVSLLQPPQYRIYQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRT 103
           INC N G +++     P+  ++ L+L GN ++ +  +E     + V L+L N+ +  +  
Sbjct: 44  INCRNLGLSSIPK-NFPESTVF-LYLTGNNISYINESELTGLHSLVALYLDNSNILYVYP 101

Query: 104 GAFSGLKTLKRLHLNNNKLEILREDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVL 163
            AF  L+ L  L LNNN ++ L    F GL +L  L   YN +S +  G F+ L  ++ L
Sbjct: 102 KAFVQLRHLYFLFLNNNFIKRLDPGIFKGLLNLRNLYLQYNQVSFVPRGVFNDLVSVQYL 161

Query: 164 ILNDNLLLSLPSNVF-RFVLLTHLDLRGNRLKVMPFAGVLEHIGGIMEIQLEEN 216
            L  N L  L S  F   V L  LDL  N +  +  +G  +H+  +  + L  N
Sbjct: 162 NLQRNRLTVLGSGTFVGMVALRILDLSNNNILRISESG-FQHLENLACLYLGSN 214



 Score = 67.8 bits (164), Expect = 4e-11
 Identities = 42/157 (26%), Positives = 79/157 (50%), Gaps = 2/157 (1%)

Query: 62  YRIYQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNK 121
           + +  L+L+ + +  +YP  FV   +   L L NN ++ +  G F GL  L+ L+L  N+
Sbjct: 84  HSLVALYLDNSNILYVYPKAFVQLRHLYFLFLNNNFIKRLDPGIFKGLLNLRNLYLQYNQ 143

Query: 122 LEILREDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRFV 181
           +  +    F  L S++YL    N ++ + +G F  +  L++L L++N +L +  + F+ +
Sbjct: 144 VSFVPRGVFNDLVSVQYLNLQRNRLTVLGSGTFVGMVALRILDLSNNNILRISESGFQHL 203

Query: 182 -LLTHLDLRGNRLKVMPFAGVLEHIGGIMEIQLEENP 217
             L  L L  N L  +P +   E +  +  + L  NP
Sbjct: 204 ENLACLYLGSNNLTKVP-SNAFEVLKSLRRLSLSHNP 239



 Score = 35.4 bits (80), Expect = 0.22
 Identities = 27/81 (33%), Positives = 38/81 (46%), Gaps = 1/81 (1%)

Query: 378 KKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFTNL-TSLRRLYLNGNYLE 436
           K L L+ N L+ +  +      +L  L L  NRI  I    F N+  SL+ L L+ N L 
Sbjct: 279 KHLILSHNDLENLNSDTFSLLKNLIYLKLDRNRIISIDNDTFENMGASLKILNLSFNNLT 338

Query: 437 VLYPSMFDGLQSLQYLYLEYN 457
            L+P +   L SL +L    N
Sbjct: 339 ALHPRVLKPLSSLIHLQANSN 359


>gi|34577057 fibronectin leucine rich transmembrane protein 1 [Homo
           sapiens]
          Length = 674

 Score = 96.3 bits (238), Expect = 1e-19
 Identities = 76/228 (33%), Positives = 119/228 (52%), Gaps = 17/228 (7%)

Query: 352 DNGLN-VNCQERKFTNISDLQPKPTSPKKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNR 410
           DN ++ V+ +E  F +   L       K L+L+ N+L ++     L ++ L+ L L +NR
Sbjct: 160 DNSVSTVSIEEDAFADSKQL-------KLLFLSRNHLSSIPSG--LPHT-LEELRLDDNR 209

Query: 411 IAVIQEGAFTNLTSLRRLYLNGNYL--EVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFD 468
           I+ I   AF  L SLRRL L+GN L  + +    F  LQ+L  L L  N +    PL   
Sbjct: 210 ISTIPLHAFKGLNSLRRLVLDGNLLANQRIADDTFSRLQNLTELSLVRNSLAA-PPLNLP 268

Query: 469 ALINLQLLFLNNNLLRSLPDNIFGGTA-LTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQ 527
           +  +LQ L+L +N +  +P N       L RL+L NN+ + LP +G+ D L    Q+ L+
Sbjct: 269 SA-HLQKLYLQDNAISHIPYNTLAKMRELERLDLSNNNLTTLP-RGLFDDLGNLAQLLLR 326

Query: 528 ENPWDCTCDIMGLKDWTEHANSPVIINEVTCESPAKHAGEILKFLGRE 575
            NPW C C++M L+DW +   + V +  + C+ P K  G  +K +  E
Sbjct: 327 NNPWFCGCNLMWLRDWVKARAAVVNVRGLMCQGPEKVRGMAIKDITSE 374



 Score = 78.6 bits (192), Expect = 2e-14
 Identities = 60/207 (28%), Positives = 103/207 (49%), Gaps = 14/207 (6%)

Query: 91  LHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKL--EILREDTFLGLESLEYLQADYNYISA 148
           L L +N +  I   AF GL +L+RL L+ N L  + + +DTF  L++L  L    N ++A
Sbjct: 203 LRLDDNRISTIPLHAFKGLNSLRRLVLDGNLLANQRIADDTFSRLQNLTELSLVRNSLAA 262

Query: 149 IEAGAFSKLNKLKVLILNDNLLLSLPSNVF-RFVLLTHLDLRGNRLKVMPFAGVLEHIGG 207
                 S    L+ L L DN +  +P N   +   L  LDL  N L  +P  G+ + +G 
Sbjct: 263 PPLNLPSA--HLQKLYLQDNAISHIPYNTLAKMRELERLDLSNNNLTTLP-RGLFDDLGN 319

Query: 208 IMEIQLEENPWNCTCDLLPLKAWLD--TITVFVGEIVCETPFRLHGKDVTQLTRQ-DLC- 263
           + ++ L  NPW C C+L+ L+ W+      V V  ++C+ P ++ G  +  +T + D C 
Sbjct: 320 LAQLLLRNNPWFCGCNLMWLRDWVKARAAVVNVRGLMCQGPEKVRGMAIKDITSEMDECF 379

Query: 264 ---PRKSASDSSQRGSHADTHVQRLSP 287
              P+   ++++ + + A  H    +P
Sbjct: 380 ETGPQGGVANAAAK-TTASNHASATTP 405



 Score = 33.1 bits (74), Expect = 1.1
 Identities = 19/64 (29%), Positives = 27/64 (42%)

Query: 57  LQPPQYRIYQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLH 116
           L  P   + +L+L  N ++ +  N          L L NN L  +  G F  L  L +L 
Sbjct: 265 LNLPSAHLQKLYLQDNAISHIPYNTLAKMRELERLDLSNNNLTTLPRGLFDDLGNLAQLL 324

Query: 117 LNNN 120
           L NN
Sbjct: 325 LRNN 328


>gi|38202222 fibronectin leucine rich transmembrane protein 3
           precursor [Homo sapiens]
          Length = 649

 Score = 95.9 bits (237), Expect = 1e-19
 Identities = 75/242 (30%), Positives = 120/242 (49%), Gaps = 15/242 (6%)

Query: 380 LYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFTNLTSLRRLYLNGNYLEV-- 437
           L+L+ N+L T+         +++ L L +NRI+ I   +   LTSL+RL L+GN L    
Sbjct: 159 LFLSRNHLSTIPWG---LPRTIEELRLDDNRISTISSPSLQGLTSLKRLVLDGNLLNNHG 215

Query: 438 LYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNNNLLRSLPDNIFGGTA-L 496
           L   +F  L +L  L L  N +    P+      NL+ L+L +N +  +P N F     L
Sbjct: 216 LGDKVFFNLVNLTELSLVRNSLTAA-PVNLPGT-NLRKLYLQDNHINRVPPNAFSYLRQL 273

Query: 497 TRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMGLKDWTEHANSPVIINEV 556
            RL++ NN+ S+LP +G+ D L    Q+ L+ NPW C C +  ++DW +     V +  +
Sbjct: 274 YRLDMSNNNLSNLP-QGIFDDLDNITQLILRNNPWYCGCKMKWVRDWLQSLPVKVNVRGL 332

Query: 557 TCESPAKHAGEILKFLGREAI-CPDSPNLSDGTVLSMNHNTDTPRSLSVSPSSYPELHTE 615
            C++P K  G  +K L  E   C DS     G V ++   T  P ++  +   +P   T+
Sbjct: 333 MCQAPEKVRGMAIKDLNAELFDCKDS-----GIVSTIQITTAIPNTVYPAQGQWPAPVTK 387

Query: 616 VP 617
            P
Sbjct: 388 QP 389



 Score = 74.7 bits (182), Expect = 3e-13
 Identities = 66/241 (27%), Positives = 110/241 (45%), Gaps = 22/241 (9%)

Query: 91  LHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLEI--LREDTFLGLESLEYLQADYNYISA 148
           L L +N +  I + +  GL +LKRL L+ N L    L +  F  L +L  L    N ++A
Sbjct: 180 LRLDDNRISTISSPSLQGLTSLKRLVLDGNLLNNHGLGDKVFFNLVNLTELSLVRNSLTA 239

Query: 149 IEAGAFSKLNKLKVLILNDNLLLSLPSNVFRFVL-LTHLDLRGNRLKVMPFAGVLEHIGG 207
                      L+ L L DN +  +P N F ++  L  LD+  N L  +P  G+ + +  
Sbjct: 240 APVNLPG--TNLRKLYLQDNHINRVPPNAFSYLRQLYRLDMSNNNLSNLP-QGIFDDLDN 296

Query: 208 IMEIQLEENPWNCTCDLLPLKAWLDTITVFVG--EIVCETPFRLHGKDVTQLTRQDLCPR 265
           I ++ L  NPW C C +  ++ WL ++ V V    ++C+ P ++ G  +  L  +     
Sbjct: 297 ITQLILRNNPWYCGCKMKWVRDWLQSLPVKVNVRGLMCQAPEKVRGMAIKDLNAE----- 351

Query: 266 KSASDSSQRGSHADTHVQRLSP-TMNPALNPTRAPKASRPPKMRNRPTPRVTVSKDRQSF 324
               D    G  +   +    P T+ PA     AP  ++ P ++N   P++T  KD Q+ 
Sbjct: 352 --LFDCKDSGIVSTIQITTAIPNTVYPAQGQWPAP-VTKQPDIKN---PKLT--KDHQTT 403

Query: 325 G 325
           G
Sbjct: 404 G 404



 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 53/192 (27%), Positives = 80/192 (41%), Gaps = 14/192 (7%)

Query: 1   MLSGVW--FLSVLTVAGILQTESRKTAKDICKIRCLCEEKENVLNINCENKGFTTVSLLQ 58
           M+S  W  FL    +   LQ          C   C C+       I C ++  T++    
Sbjct: 1   MISAAWSIFLIGTKIGLFLQVAPLSVMAKSCPSVCRCDAGF----IYCNDRFLTSIPTGI 56

Query: 59  PPQYRIYQLFLNGNLLTRL-YPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHL 117
           P       L+L  N +     P++  N      ++L +N L E  T      K +K LHL
Sbjct: 57  PEDATT--LYLQNNQINNAGIPSDLKNLLKVERIYLYHNSLDEFPTNL---PKYVKELHL 111

Query: 118 NNNKLEILREDTFLGLESLEYLQADYNYISA--IEAGAFSKLNKLKVLILNDNLLLSLPS 175
             N +  +  D+   +  LE L  D N +SA  IE GAF   N L++L L+ N L ++P 
Sbjct: 112 QENNIRTITYDSLSKIPYLEELHLDDNSVSAVSIEEGAFRDSNYLRLLFLSRNHLSTIPW 171

Query: 176 NVFRFVLLTHLD 187
            + R +    LD
Sbjct: 172 GLPRTIEELRLD 183



 Score = 37.0 bits (84), Expect = 0.077
 Identities = 20/68 (29%), Positives = 31/68 (45%)

Query: 53  TVSLLQPPQYRIYQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTL 112
           T + +  P   + +L+L  N + R+ PN F        L + NN L  +  G F  L  +
Sbjct: 238 TAAPVNLPGTNLRKLYLQDNHINRVPPNAFSYLRQLYRLDMSNNNLSNLPQGIFDDLDNI 297

Query: 113 KRLHLNNN 120
            +L L NN
Sbjct: 298 TQLILRNN 305



 Score = 35.8 bits (81), Expect = 0.17
 Identities = 24/77 (31%), Positives = 38/77 (49%), Gaps = 2/77 (2%)

Query: 375 TSPKKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFTNLTSLRRLYLNGN- 433
           T+ +KLYL  N++  V  N       L  L + NN ++ + +G F +L ++ +L L  N 
Sbjct: 247 TNLRKLYLQDNHINRVPPNAFSYLRQLYRLDMSNNNLSNLPQGIFDDLDNITQLILRNNP 306

Query: 434 -YLEVLYPSMFDGLQSL 449
            Y       + D LQSL
Sbjct: 307 WYCGCKMKWVRDWLQSL 323



 Score = 32.7 bits (73), Expect = 1.4
 Identities = 18/54 (33%), Positives = 30/54 (55%)

Query: 86  SNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLEILREDTFLGLESLEYL 139
           +N   L+L +N +  +   AFS L+ L RL ++NN L  L +  F  L+++  L
Sbjct: 247 TNLRKLYLQDNHINRVPPNAFSYLRQLYRLDMSNNNLSNLPQGIFDDLDNITQL 300


>gi|7019383 fibronectin leucine rich transmembrane protein 3
           precursor [Homo sapiens]
          Length = 649

 Score = 95.9 bits (237), Expect = 1e-19
 Identities = 75/242 (30%), Positives = 120/242 (49%), Gaps = 15/242 (6%)

Query: 380 LYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFTNLTSLRRLYLNGNYLEV-- 437
           L+L+ N+L T+         +++ L L +NRI+ I   +   LTSL+RL L+GN L    
Sbjct: 159 LFLSRNHLSTIPWG---LPRTIEELRLDDNRISTISSPSLQGLTSLKRLVLDGNLLNNHG 215

Query: 438 LYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNNNLLRSLPDNIFGGTA-L 496
           L   +F  L +L  L L  N +    P+      NL+ L+L +N +  +P N F     L
Sbjct: 216 LGDKVFFNLVNLTELSLVRNSLTAA-PVNLPGT-NLRKLYLQDNHINRVPPNAFSYLRQL 273

Query: 497 TRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMGLKDWTEHANSPVIINEV 556
            RL++ NN+ S+LP +G+ D L    Q+ L+ NPW C C +  ++DW +     V +  +
Sbjct: 274 YRLDMSNNNLSNLP-QGIFDDLDNITQLILRNNPWYCGCKMKWVRDWLQSLPVKVNVRGL 332

Query: 557 TCESPAKHAGEILKFLGREAI-CPDSPNLSDGTVLSMNHNTDTPRSLSVSPSSYPELHTE 615
            C++P K  G  +K L  E   C DS     G V ++   T  P ++  +   +P   T+
Sbjct: 333 MCQAPEKVRGMAIKDLNAELFDCKDS-----GIVSTIQITTAIPNTVYPAQGQWPAPVTK 387

Query: 616 VP 617
            P
Sbjct: 388 QP 389



 Score = 74.7 bits (182), Expect = 3e-13
 Identities = 66/241 (27%), Positives = 110/241 (45%), Gaps = 22/241 (9%)

Query: 91  LHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLEI--LREDTFLGLESLEYLQADYNYISA 148
           L L +N +  I + +  GL +LKRL L+ N L    L +  F  L +L  L    N ++A
Sbjct: 180 LRLDDNRISTISSPSLQGLTSLKRLVLDGNLLNNHGLGDKVFFNLVNLTELSLVRNSLTA 239

Query: 149 IEAGAFSKLNKLKVLILNDNLLLSLPSNVFRFVL-LTHLDLRGNRLKVMPFAGVLEHIGG 207
                      L+ L L DN +  +P N F ++  L  LD+  N L  +P  G+ + +  
Sbjct: 240 APVNLPG--TNLRKLYLQDNHINRVPPNAFSYLRQLYRLDMSNNNLSNLP-QGIFDDLDN 296

Query: 208 IMEIQLEENPWNCTCDLLPLKAWLDTITVFVG--EIVCETPFRLHGKDVTQLTRQDLCPR 265
           I ++ L  NPW C C +  ++ WL ++ V V    ++C+ P ++ G  +  L  +     
Sbjct: 297 ITQLILRNNPWYCGCKMKWVRDWLQSLPVKVNVRGLMCQAPEKVRGMAIKDLNAE----- 351

Query: 266 KSASDSSQRGSHADTHVQRLSP-TMNPALNPTRAPKASRPPKMRNRPTPRVTVSKDRQSF 324
               D    G  +   +    P T+ PA     AP  ++ P ++N   P++T  KD Q+ 
Sbjct: 352 --LFDCKDSGIVSTIQITTAIPNTVYPAQGQWPAP-VTKQPDIKN---PKLT--KDHQTT 403

Query: 325 G 325
           G
Sbjct: 404 G 404



 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 53/192 (27%), Positives = 80/192 (41%), Gaps = 14/192 (7%)

Query: 1   MLSGVW--FLSVLTVAGILQTESRKTAKDICKIRCLCEEKENVLNINCENKGFTTVSLLQ 58
           M+S  W  FL    +   LQ          C   C C+       I C ++  T++    
Sbjct: 1   MISAAWSIFLIGTKIGLFLQVAPLSVMAKSCPSVCRCDAGF----IYCNDRFLTSIPTGI 56

Query: 59  PPQYRIYQLFLNGNLLTRL-YPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHL 117
           P       L+L  N +     P++  N      ++L +N L E  T      K +K LHL
Sbjct: 57  PEDATT--LYLQNNQINNAGIPSDLKNLLKVERIYLYHNSLDEFPTNL---PKYVKELHL 111

Query: 118 NNNKLEILREDTFLGLESLEYLQADYNYISA--IEAGAFSKLNKLKVLILNDNLLLSLPS 175
             N +  +  D+   +  LE L  D N +SA  IE GAF   N L++L L+ N L ++P 
Sbjct: 112 QENNIRTITYDSLSKIPYLEELHLDDNSVSAVSIEEGAFRDSNYLRLLFLSRNHLSTIPW 171

Query: 176 NVFRFVLLTHLD 187
            + R +    LD
Sbjct: 172 GLPRTIEELRLD 183



 Score = 37.0 bits (84), Expect = 0.077
 Identities = 20/68 (29%), Positives = 31/68 (45%)

Query: 53  TVSLLQPPQYRIYQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTL 112
           T + +  P   + +L+L  N + R+ PN F        L + NN L  +  G F  L  +
Sbjct: 238 TAAPVNLPGTNLRKLYLQDNHINRVPPNAFSYLRQLYRLDMSNNNLSNLPQGIFDDLDNI 297

Query: 113 KRLHLNNN 120
            +L L NN
Sbjct: 298 TQLILRNN 305



 Score = 35.8 bits (81), Expect = 0.17
 Identities = 24/77 (31%), Positives = 38/77 (49%), Gaps = 2/77 (2%)

Query: 375 TSPKKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFTNLTSLRRLYLNGN- 433
           T+ +KLYL  N++  V  N       L  L + NN ++ + +G F +L ++ +L L  N 
Sbjct: 247 TNLRKLYLQDNHINRVPPNAFSYLRQLYRLDMSNNNLSNLPQGIFDDLDNITQLILRNNP 306

Query: 434 -YLEVLYPSMFDGLQSL 449
            Y       + D LQSL
Sbjct: 307 WYCGCKMKWVRDWLQSL 323



 Score = 32.7 bits (73), Expect = 1.4
 Identities = 18/54 (33%), Positives = 30/54 (55%)

Query: 86  SNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLEILREDTFLGLESLEYL 139
           +N   L+L +N +  +   AFS L+ L RL ++NN L  L +  F  L+++  L
Sbjct: 247 TNLRKLYLQDNHINRVPPNAFSYLRQLYRLDMSNNNLSNLPQGIFDDLDNITQL 300


>gi|153251229 chondroadherin precursor [Homo sapiens]
          Length = 359

 Score = 95.5 bits (236), Expect = 2e-19
 Identities = 66/218 (30%), Positives = 99/218 (45%), Gaps = 34/218 (15%)

Query: 380 LYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFTNLTSLRRLYLNGNYLEVLY 439
           LYL  N +  + +  L    +L +L L NN+I  ++ GAF     LR LYL+ N L  L 
Sbjct: 128 LYLDHNKVTELPRGLLSPLVNLFILQLNNNKIRELRAGAFQGAKDLRWLYLSENALSSLQ 187

Query: 440 PSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNNNLLRSLPDNIF-------- 491
           P   D +++L   +++ N +          L  ++ L L++N L+S+PDN F        
Sbjct: 188 PGALDDVENLAKFHVDRNQLSSYPSAALSKLRVVEELKLSHNPLKSIPDNAFQSFGRYLE 247

Query: 492 ------------------GGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDC 533
                             G T L  ++L NN  + LP     D L     + L  NPW C
Sbjct: 248 TLWLDNTNLEKFSDGAFLGVTTLKHVHLENNRLNQLPSNFPFDSLET---LALTNNPWKC 304

Query: 534 TCDIMGLKDWTE-HANSPVIINEVTCESPAKHAGEILK 570
           TC + GL+ W E  A+ P    + TC SPAK  G+ ++
Sbjct: 305 TCQLRGLRRWLEAKASRP----DATCASPAKFKGQHIR 338



 Score = 88.6 bits (218), Expect = 2e-17
 Identities = 66/241 (27%), Positives = 102/241 (42%), Gaps = 35/241 (14%)

Query: 67  LFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLEILR 126
           L+L+ N +T L         N   L L NN ++E+R GAF G K L+ L+L+ N L  L+
Sbjct: 128 LYLDHNKVTELPRGLLSPLVNLFILQLNNNKIRELRAGAFQGAKDLRWLYLSENALSSLQ 187

Query: 127 EDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFR------- 179
                 +E+L     D N +S+  + A SKL  ++ L L+ N L S+P N F+       
Sbjct: 188 PGALDDVENLAKFHVDRNQLSSYPSAALSKLRVVEELKLSHNPLKSIPDNAFQSFGRYLE 247

Query: 180 -------------------FVLLTHLDLRGNRLKVMPFAGVLEHIGGIMEIQLEENPWNC 220
                                 L H+ L  NRL  +P     +    +  + L  NPW C
Sbjct: 248 TLWLDNTNLEKFSDGAFLGVTTLKHVHLENNRLNQLPSNFPFD---SLETLALTNNPWKC 304

Query: 221 TCDLLPLKAWLDTITVFVGEIVCETPFRLHGKDVTQLTRQDLCPRKSASDSSQRGSHADT 280
           TC L  L+ WL+       +  C +P +  G+ +     +D    +S    ++R   A  
Sbjct: 305 TCQLRGLRRWLEA-KASRPDATCASPAKFKGQHI-----RDTDAFRSCKFPTKRSKKAGR 358

Query: 281 H 281
           H
Sbjct: 359 H 359



 Score = 77.8 bits (190), Expect = 4e-14
 Identities = 63/196 (32%), Positives = 84/196 (42%), Gaps = 9/196 (4%)

Query: 335 PVPLTCPSSCVCTSQSSDNGLNVNCQERKFTNISDLQPKPTSPKKLYLTGNYLQTVYKND 394
           P    CP +C C S       +V C +     I  +  K    K L L  N    +  N 
Sbjct: 18  PALAACPQNCHCHSDLQ----HVICDKVGLQKIPKVSEKT---KLLNLQRNNFPVLAANS 70

Query: 395 LLEYSSLDLLHLGNNRIAVIQEGAFTNLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYL 454
                +L  LHL + +I  +  GAF  L  L  LYL+ N + VL    FD L  L YLYL
Sbjct: 71  FRAMPNLVSLHLQHCQIREVAAGAFRGLKQLIYLYLSHNDIRVLRAGAFDDLTELTYLYL 130

Query: 455 EYNVIKEIKPLTFDALINLQLLFLNNNLLRSLPDNIF-GGTALTRLNLRNNHFSHLPVKG 513
           ++N + E+       L+NL +L LNNN +R L    F G   L  L L  N  S L   G
Sbjct: 131 DHNKVTELPRGLLSPLVNLFILQLNNNKIRELRAGAFQGAKDLRWLYLSENALSSLQ-PG 189

Query: 514 VLDQLPAFIQIDLQEN 529
            LD +    +  +  N
Sbjct: 190 ALDDVENLAKFHVDRN 205



 Score = 72.8 bits (177), Expect = 1e-12
 Identities = 61/217 (28%), Positives = 100/217 (46%), Gaps = 13/217 (5%)

Query: 1   MLSGVWFLSVLTVAGILQTESRKTAKDICKIRCLCEEKENVLNINCENKGFTTVSLLQPP 60
           M+  +  LS+  +AG+L       A   C   C C    ++ ++ C+  G   +  +   
Sbjct: 1   MVRPMLLLSLGLLAGLLP------ALAACPQNCHCHS--DLQHVICDKVGLQKIPKVSE- 51

Query: 61  QYRIYQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNN 120
             +   L L  N    L  N F    N V+LHL +  ++E+  GAF GLK L  L+L++N
Sbjct: 52  --KTKLLNLQRNNFPVLAANSFRAMPNLVSLHLQHCQIREVAAGAFRGLKQLIYLYLSHN 109

Query: 121 KLEILREDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRF 180
            + +LR   F  L  L YL  D+N ++ +  G  S L  L +L LN+N +  L +  F+ 
Sbjct: 110 DIRVLRAGAFDDLTELTYLYLDHNKVTELPRGLLSPLVNLFILQLNNNKIRELRAGAFQG 169

Query: 181 VL-LTHLDLRGNRLKVMPFAGVLEHIGGIMEIQLEEN 216
              L  L L  N L  +   G L+ +  + +  ++ N
Sbjct: 170 AKDLRWLYLSENALSSLQ-PGALDDVENLAKFHVDRN 205


>gi|10190722 leucine-rich repeats and transmembrane domains 1 [Homo
           sapiens]
          Length = 345

 Score = 93.2 bits (230), Expect = 9e-19
 Identities = 78/287 (27%), Positives = 124/287 (43%), Gaps = 36/287 (12%)

Query: 29  CKIRCLCEEKENVLNINCENKGFTTVSLLQPPQYRIYQLFLNGNLLTRLYPNEFVNYSNA 88
           C  +C C+   N   ++C  +G   +    PPQ R                         
Sbjct: 21  CPDKCYCQSSTNF--VDCSQQGLAEIPSHLPPQTR------------------------- 53

Query: 89  VTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLEILREDTFLGLESLEYLQADYNYISA 148
            TLHL +N +  +   AF  +  L  L+L+NN L  L    F GL+ L+ L    N + +
Sbjct: 54  -TLHLQDNQIHHLPAFAFRSVPWLMTLNLSNNSLSNLAPGAFHGLQHLQVLNLTQNSLLS 112

Query: 149 IEAGAFSKLNKLKVLILNDNLLLSLPSNVFR-FVLLTHLDLRGNRLKVMPFAGVLEHIGG 207
           +E+  F  L +L+ L L+ N +  LP+++   +  LT L ++ N+L+ +  A +LE +  
Sbjct: 113 LESRLFHSLPQLRELDLSSNNISHLPTSLGETWENLTILAVQQNQLQQLDRA-LLESMPS 171

Query: 208 IMEIQLEENPWNCTCDLLPLKAWLDTITVFVG---EIVCETPFRLHGKDVTQLTRQ--DL 262
           +  + L++N W C C LL LK WL+      G    I+CE+P    GKD+ ++  +    
Sbjct: 172 VRLLLLKDNLWKCNCHLLGLKLWLEKFVYKGGLTDGIICESPDTWKGKDLLRIPHELYQP 231

Query: 263 CPRKSASD-SSQRGSHADTHVQRLSPTMNPALNPTRAPKASRPPKMR 308
           CP  +    SSQ       H   L P  N         +    PK R
Sbjct: 232 CPLPAPDPVSSQAQWPGSAHGVVLRPPENHNAGERELLECELKPKPR 278



 Score = 83.2 bits (204), Expect = 9e-16
 Identities = 87/325 (26%), Positives = 134/325 (41%), Gaps = 52/325 (16%)

Query: 336 VPLTCPSSCVCTSQSSDNGLNVNCQERKFTNISDLQPKPTSPKKLYLTGNYLQTVYKNDL 395
           V  +CP  C C  QSS N   V+C ++    I    P  T                    
Sbjct: 17  VVCSCPDKCYC--QSSTNF--VDCSQQGLAEIPSHLPPQTRT------------------ 54

Query: 396 LEYSSLDLLHLGNNRIAVIQEGAFTNLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLE 455
                   LHL +N+I  +   AF ++  L  L L+ N L  L P  F GLQ LQ L L 
Sbjct: 55  --------LHLQDNQIHHLPAFAFRSVPWLMTLNLSNNSLSNLAPGAFHGLQHLQVLNLT 106

Query: 456 YNVIKEIKPLTFDALINLQLLFLNNNLLRSLPDNIFGGT--ALTRLNLRNNHFSHLPVKG 513
            N +  ++   F +L  L+ L L++N +  LP ++ G T   LT L ++ N    L  + 
Sbjct: 107 QNSLLSLESRLFHSLPQLRELDLSSNNISHLPTSL-GETWENLTILAVQQNQLQQLD-RA 164

Query: 514 VLDQLPAFIQIDLQENPWDCTCDIMGLKDWTE-HANSPVIINEVTCESPAKHAGEILKFL 572
           +L+ +P+   + L++N W C C ++GLK W E       + + + CESP    G+ L  +
Sbjct: 165 LLESMPSVRLLLLKDNLWKCNCHLLGLKLWLEKFVYKGGLTDGIICESPDTWKGKDLLRI 224

Query: 573 GREAI--CP-----------DSPNLSDGTVL--SMNHNTDTPRSL--SVSPSSYPELHTE 615
             E    CP             P  + G VL    NHN      L   + P   P     
Sbjct: 225 PHELYQPCPLPAPDPVSSQAQWPGSAHGVVLRPPENHNAGERELLECELKPKPRPANLRH 284

Query: 616 VPLSVLILGLLVVFILSVCFGAGLF 640
              +V+I G++   +  +   A ++
Sbjct: 285 AIATVIITGVVCGIVCLMMLAAAIY 309


>gi|84781739 leucine-rich repeats and transmembrane domains 2 [Homo
           sapiens]
          Length = 370

 Score = 91.7 bits (226), Expect = 3e-18
 Identities = 76/291 (26%), Positives = 110/291 (37%), Gaps = 36/291 (12%)

Query: 29  CKIRCLCEEKENVLNINCENKGFTTVSLLQPPQYRIYQLFLNGNLLTRLYPNEFVNYSNA 88
           C   C C+ +   L ++C   G TTV    P   R   L L  N L+ L    F N S+ 
Sbjct: 39  CPFSCKCDSRS--LEVDCSGLGLTTVPPDVPAATRT--LLLLNNKLSALPSWAFANLSSL 94

Query: 89  VTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLEILREDTFLGLESLEYLQADYNYISA 148
             L L NN L  +    F  L  L  L L NN +  L  D       L +L    N ++ 
Sbjct: 95  QRLDLSNNFLDRLPRSIFGDLTNLTELQLRNNSIRTLDRDLLRHSPLLRHLDLSINGLAQ 154

Query: 149 IEAGAFSKLNKLKVLILNDNLLLSLPSNVFRFVLLTHLDLRGNRLKVMPFAGVLEHIGGI 208
           +  G F  L  L+ L L  N L +L    F                        E +  +
Sbjct: 155 LPPGLFDGLLALRSLSLRSNRLQNLDRLTF------------------------EPLANL 190

Query: 209 MEIQLEENPWNCTCDLLPLKAWLDTITVFVG---EIVCETPFRLHGKDVTQLTRQ--DLC 263
             +Q+ +NPW C C+L   K W++  +   G   ++ C  P  L GKD+  +  +  + C
Sbjct: 191 QLLQVGDNPWECDCNLREFKHWMEWFSYRGGRLDQLACTLPKELRGKDMRMVPMEMFNYC 250

Query: 264 PRKSASDSSQRGSHADTHVQRLSP---TMNPALNPTRAPKASRPPKMRNRP 311
            +    +SS           + SP      P   P   P  + P K R+RP
Sbjct: 251 SQLEDENSSAGLDIPGPPCTKASPEPAKPKPGAEPEPEPSTACPQKQRHRP 301



 Score = 66.2 bits (160), Expect = 1e-10
 Identities = 51/165 (30%), Positives = 76/165 (46%), Gaps = 26/165 (15%)

Query: 339 TCPSSCVCTSQSSDNGLNVNCQERKFTNISDLQPKPT----------------------S 376
           TCP SC C S+S    L V+C     T +    P  T                      S
Sbjct: 38  TCPFSCKCDSRS----LEVDCSGLGLTTVPPDVPAATRTLLLLNNKLSALPSWAFANLSS 93

Query: 377 PKKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFTNLTSLRRLYLNGNYLE 436
            ++L L+ N+L  + ++   + ++L  L L NN I  +      +   LR L L+ N L 
Sbjct: 94  LQRLDLSNNFLDRLPRSIFGDLTNLTELQLRNNSIRTLDRDLLRHSPLLRHLDLSINGLA 153

Query: 437 VLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNNN 481
            L P +FDGL +L+ L L  N ++ +  LTF+ L NLQLL + +N
Sbjct: 154 QLPPGLFDGLLALRSLSLRSNRLQNLDRLTFEPLANLQLLQVGDN 198


>gi|30425553 reticulon 4 receptor-like 1 [Homo sapiens]
          Length = 441

 Score = 91.7 bits (226), Expect = 3e-18
 Identities = 86/295 (29%), Positives = 118/295 (40%), Gaps = 53/295 (17%)

Query: 327 IMVYQTKSPVPLTCPSSCVCTSQSSDNGLNVNCQERKFTNISD----------------- 369
           +++   + P+   CP  CVC        + V+CQ   F  I +                 
Sbjct: 12  LLLVAAELPLGGGCPRDCVCYPAP----MTVSCQAHNFAAIPEGIPVDSERVFLQNNRIG 67

Query: 370 -LQPKPTSPKK--LYLTGNYLQTVYKNDLLEYSSLDLLHLGNNR-IAVIQEGAFTNLTSL 425
            LQP   SP    L++  N +  ++ +    +  L+ L LG+NR +  +    F  L  L
Sbjct: 68  LLQPGHFSPAMVTLWIYSNNITYIHPSTFEGFVHLEELDLGDNRQLRTLAPETFQGLVKL 127

Query: 426 RRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNNNLLRS 485
             LYL    L  L   +F GL SLQYLYL+ N I+ ++   F  L+NL  LFL+ N L S
Sbjct: 128 HALYLYKCGLSALPAGVFGGLHSLQYLYLQDNHIEYLQDDIFVDLVNLSHLFLHGNKLWS 187

Query: 486 LPDNIFGGTA-------------------------LTRLNLRNNHFSHLPVKGVLDQLPA 520
           L    F G                           LT L L NN  S L  +  L  L A
Sbjct: 188 LGPGTFRGLVNLDRLLLHENQLQWVHHKAFHDLRRLTTLFLFNNSLSELQGE-CLAPLGA 246

Query: 521 FIQIDLQENPWDCTCDIMGLKDWTEHANSPVIINEVTCESPAKHAGEILKFLGRE 575
              + L  NPWDC C    L +W +        + V C SP    G+ LK L  E
Sbjct: 247 LEFLRLNGNPWDCGCRARSLWEWLQRFRGS--SSAVPCVSPGLRHGQDLKLLRAE 299



 Score = 88.2 bits (217), Expect = 3e-17
 Identities = 79/303 (26%), Positives = 129/303 (42%), Gaps = 38/303 (12%)

Query: 54  VSLLQPPQYR--IYQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNN--------------- 96
           + LLQP  +   +  L++  N +T ++P+ F  + +   L LG+N               
Sbjct: 66  IGLLQPGHFSPAMVTLWIYSNNITYIHPSTFEGFVHLEELDLGDNRQLRTLAPETFQGLV 125

Query: 97  ----------GLQEIRTGAFSGLKTLKRLHLNNNKLEILREDTFLGLESLEYLQADYNYI 146
                     GL  +  G F GL +L+ L+L +N +E L++D F+ L +L +L    N +
Sbjct: 126 KLHALYLYKCGLSALPAGVFGGLHSLQYLYLQDNHIEYLQDDIFVDLVNLSHLFLHGNKL 185

Query: 147 SAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRFV-LLTHLDLRGNRLKVMPFAGVLEHI 205
            ++  G F  L  L  L+L++N L  +    F  +  LT L L  N L  +     L  +
Sbjct: 186 WSLGPGTFRGLVNLDRLLLHENQLQWVHHKAFHDLRRLTTLFLFNNSLSELQ-GECLAPL 244

Query: 206 GGIMEIQLEENPWNCTCDLLPLKAWLDTITVFVGEIVCETPFRLHGKDVTQLTRQDLCPR 265
           G +  ++L  NPW+C C    L  WL         + C +P   HG+D+  L  +D    
Sbjct: 245 GALEFLRLNGNPWDCGCRARSLWEWLQRFRGSSSAVPCVSPGLRHGQDLKLLRAEDFRNC 304

Query: 266 KSASDSSQRGSHADTHVQRLSPTMNPALN-PTRA--------PKASRPPKMRNRPTPRVT 316
              +   Q  SH  T   R +   + + + PTR+        P   +P K    P  R  
Sbjct: 305 TGPASPHQIKSHTLTTTDRAARKEHHSPHGPTRSKGHPHGPRPGHRKPGKNCTNPRNRNQ 364

Query: 317 VSK 319
           +SK
Sbjct: 365 ISK 367


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.136    0.404 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,201,994
Number of Sequences: 37866
Number of extensions: 1682503
Number of successful extensions: 8136
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 225
Number of HSP's successfully gapped in prelim test: 77
Number of HSP's that attempted gapping in prelim test: 4747
Number of HSP's gapped (non-prelim): 1602
length of query: 845
length of database: 18,247,518
effective HSP length: 111
effective length of query: 734
effective length of database: 14,044,392
effective search space: 10308583728
effective search space used: 10308583728
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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