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Search of human proteins with 22095349
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|22095349 WD and tetratricopeptide repeats 1 [Homo sapiens]
(676 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|22095349 WD and tetratricopeptide repeats 1 [Homo sapiens] 1397 0.0
gi|30089954 H326 [Homo sapiens] 134 4e-31
gi|211904182 DDB1 and CUL4 associated factor 8-like 2 [Homo sapi... 122 1e-27
gi|63252910 IQ motif and WD repeats 1 isoform b [Homo sapiens] 119 1e-26
gi|63252908 IQ motif and WD repeats 1 isoform a [Homo sapiens] 119 1e-26
gi|62988359 DDB1 and CUL4 associated factor 8-like 1 [Homo sapiens] 107 3e-23
gi|55741849 WD repeat domain 22 [Homo sapiens] 81 4e-15
gi|56181387 STIP1 homology and U-box containing protein 1 [Homo ... 66 1e-10
gi|4506921 small glutamine-rich tetratricopeptide [Homo sapiens] 64 6e-10
gi|207029439 retinoblastoma binding protein 4 isoform c [Homo sa... 59 1e-08
gi|207029415 retinoblastoma binding protein 4 isoform b [Homo sa... 59 1e-08
gi|5032027 retinoblastoma binding protein 4 isoform a [Homo sapi... 59 1e-08
gi|19913371 transducin (beta)-like 1 X-linked receptor 1 [Homo s... 59 1e-08
gi|5453958 protein phosphatase 5, catalytic subunit [Homo sapiens] 59 2e-08
gi|5902034 periodic tryptophan protein 1 [Homo sapiens] 59 2e-08
gi|4506439 retinoblastoma binding protein 7 [Homo sapiens] 58 3e-08
gi|5803181 stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizi... 57 4e-08
gi|83779014 katanin p80 subunit B 1 [Homo sapiens] 57 4e-08
gi|216548382 WD repeat domain 47 isoform 3 [Homo sapiens] 57 4e-08
gi|216548378 WD repeat domain 47 isoform 1 [Homo sapiens] 57 4e-08
gi|216548347 WD repeat domain 47 isoform 2 [Homo sapiens] 57 4e-08
gi|156627581 tetratricopeptide repeat domain 4 [Homo sapiens] 57 4e-08
gi|54607135 translocase of outer mitochondrial membrane 70 homol... 57 6e-08
gi|24308141 small glutamine-rich tetratricopeptide repeat (TPR)-... 56 1e-07
gi|224028289 tetratricopeptide repeat domain 28 [Homo sapiens] 55 2e-07
gi|73747840 LON peptidase N-terminal domain and ring finger 3 is... 55 2e-07
gi|213021190 transducin beta-like 1X isoform b [Homo sapiens] 55 3e-07
gi|213021188 transducin beta-like 1X isoform b [Homo sapiens] 55 3e-07
gi|213021186 transducin beta-like 1X isoform a [Homo sapiens] 55 3e-07
gi|5032159 transducin beta-like 1X isoform a [Homo sapiens] 55 3e-07
>gi|22095349 WD and tetratricopeptide repeats 1 [Homo sapiens]
Length = 676
Score = 1397 bits (3615), Expect = 0.0
Identities = 676/676 (100%), Positives = 676/676 (100%)
Query: 1 MAKVNITRDLIRRQIKERGALSFERRYHVTDPFIRRLGLEAELQGHSGCVNCLEWNEKGD 60
MAKVNITRDLIRRQIKERGALSFERRYHVTDPFIRRLGLEAELQGHSGCVNCLEWNEKGD
Sbjct: 1 MAKVNITRDLIRRQIKERGALSFERRYHVTDPFIRRLGLEAELQGHSGCVNCLEWNEKGD 60
Query: 61 LLASGSDDQHTIVWDPLHHKKLLSMHTGHTANIFSVKFLPHAGDRILITGAADSKVHVHD 120
LLASGSDDQHTIVWDPLHHKKLLSMHTGHTANIFSVKFLPHAGDRILITGAADSKVHVHD
Sbjct: 61 LLASGSDDQHTIVWDPLHHKKLLSMHTGHTANIFSVKFLPHAGDRILITGAADSKVHVHD 120
Query: 121 LTVKETIHMFGDHTNRVKRIATAPMWPNTFWSAAEDGLIRQYDLRENSKHSEVLIDLTEY 180
LTVKETIHMFGDHTNRVKRIATAPMWPNTFWSAAEDGLIRQYDLRENSKHSEVLIDLTEY
Sbjct: 121 LTVKETIHMFGDHTNRVKRIATAPMWPNTFWSAAEDGLIRQYDLRENSKHSEVLIDLTEY 180
Query: 181 CGQLVEAKCLTVNPQDNNCLAVGASGPFVRLYDIRMIHNHRKSMKQSPSAGVHTFCDRQK 240
CGQLVEAKCLTVNPQDNNCLAVGASGPFVRLYDIRMIHNHRKSMKQSPSAGVHTFCDRQK
Sbjct: 181 CGQLVEAKCLTVNPQDNNCLAVGASGPFVRLYDIRMIHNHRKSMKQSPSAGVHTFCDRQK 240
Query: 241 PLPDGAAQYYVAGHLPVKLPDYNNRLRVLVATYVTFSPNGTELLVNMGGEQVYLFDLTYK 300
PLPDGAAQYYVAGHLPVKLPDYNNRLRVLVATYVTFSPNGTELLVNMGGEQVYLFDLTYK
Sbjct: 241 PLPDGAAQYYVAGHLPVKLPDYNNRLRVLVATYVTFSPNGTELLVNMGGEQVYLFDLTYK 300
Query: 301 QRPYTFLLPRKCHSSGVQNGKMSTNGVSNGVSNGLHLHSNGFRLPESRGHVSPQVELPPY 360
QRPYTFLLPRKCHSSGVQNGKMSTNGVSNGVSNGLHLHSNGFRLPESRGHVSPQVELPPY
Sbjct: 301 QRPYTFLLPRKCHSSGVQNGKMSTNGVSNGVSNGLHLHSNGFRLPESRGHVSPQVELPPY 360
Query: 361 LERVKQQANEAFACQQWTQAIQLYSKAVQRAPHNAMLYGNRAAAYMKRKWDGDHYDALRD 420
LERVKQQANEAFACQQWTQAIQLYSKAVQRAPHNAMLYGNRAAAYMKRKWDGDHYDALRD
Sbjct: 361 LERVKQQANEAFACQQWTQAIQLYSKAVQRAPHNAMLYGNRAAAYMKRKWDGDHYDALRD 420
Query: 421 CLKAISLNPCHLKAHFRLARCLFELKYVAEALECLDDFKGKFPEQAHSSACDALGRDITA 480
CLKAISLNPCHLKAHFRLARCLFELKYVAEALECLDDFKGKFPEQAHSSACDALGRDITA
Sbjct: 421 CLKAISLNPCHLKAHFRLARCLFELKYVAEALECLDDFKGKFPEQAHSSACDALGRDITA 480
Query: 481 ALFSKNDGEEKKGPGGGAPVRLRSTSRKDSISEDEMVLRERSYDYQFRYCGHCNTTTDIK 540
ALFSKNDGEEKKGPGGGAPVRLRSTSRKDSISEDEMVLRERSYDYQFRYCGHCNTTTDIK
Sbjct: 481 ALFSKNDGEEKKGPGGGAPVRLRSTSRKDSISEDEMVLRERSYDYQFRYCGHCNTTTDIK 540
Query: 541 EANFFGSNAQYIVSGSDDGSFFIWEKETTNLVRVLQGDESIVNCLQPHPSYCFLATSGID 600
EANFFGSNAQYIVSGSDDGSFFIWEKETTNLVRVLQGDESIVNCLQPHPSYCFLATSGID
Sbjct: 541 EANFFGSNAQYIVSGSDDGSFFIWEKETTNLVRVLQGDESIVNCLQPHPSYCFLATSGID 600
Query: 601 PVVRLWNPRPESEDLTGRVVEDMEGASQANQRRMNADPLEVMLLNMGYRITGLSSGGAGA 660
PVVRLWNPRPESEDLTGRVVEDMEGASQANQRRMNADPLEVMLLNMGYRITGLSSGGAGA
Sbjct: 601 PVVRLWNPRPESEDLTGRVVEDMEGASQANQRRMNADPLEVMLLNMGYRITGLSSGGAGA 660
Query: 661 SDDEDSSEGQVQCRPS 676
SDDEDSSEGQVQCRPS
Sbjct: 661 SDDEDSSEGQVQCRPS 676
>gi|30089954 H326 [Homo sapiens]
Length = 597
Score = 134 bits (336), Expect = 4e-31
Identities = 91/309 (29%), Positives = 145/309 (46%), Gaps = 47/309 (15%)
Query: 33 FIRRLGLEAELQGHSGCVNCLEWNEKGDLLASGSDDQHTIVWDPLHHKKLLSMHTGHTAN 92
F++R L+ L+GH+GCVN L +N++G LASGSDD +VWD + + +L +GH +N
Sbjct: 179 FVQRFRLQHGLEGHTGCVNTLHFNQRGTWLASGSDDLKVVVWDWVRRQPVLDFESGHKSN 238
Query: 93 IFSVKFLPHAGDRILITGAADSKVHVHDLTVKE---TIHMFGDHTNRVKRIATAPMWPNT 149
+F KFLP++GD L A D +V V +L+ + H ++A P P T
Sbjct: 239 VFQAKFLPNSGDSTLAMCARDGQVRVAELSATQCCKNTKRVAQHKGASHKLALEPDSPCT 298
Query: 150 FWSAAEDGLIRQYDLRENSKHSEVLIDLTEYCGQLVEAKCLTVNPQDNNCLAVGASGPFV 209
F SA ED ++ DLR++ S++++ T+ + V + VNP + + AVG FV
Sbjct: 299 FLSAGEDAVVFTIDLRQDRPASKLVV--TKEKEKKVGLYTIYVNPANTHQFAVGGRDQFV 356
Query: 210 RLYDIRMIHNHRKSMKQSPSAGVHTFCDRQKPLPDGAAQYYVAGHLPVKLPDYNNRLRVL 269
R+YD R I + +G + + HL N+ +
Sbjct: 357 RIYDQRKIDENEN---------------------NGVLKKFCPHHL------VNSESKAN 389
Query: 270 VATYVTFSPNGTELLVNMGGEQVYLFDLTYKQRPYTFLLPRKCHSSGVQNGKMSTNGVSN 329
+ T + +S +GTELL + E +YLF+ HS G Q K +N
Sbjct: 390 I-TCLVYSHDGTELLASYNDEDIYLFN--------------SSHSDGAQYVKRYKGHRNN 434
Query: 330 GVSNGLHLH 338
G++ +
Sbjct: 435 ATVKGVNFY 443
Score = 95.5 bits (236), Expect = 1e-19
Identities = 64/199 (32%), Positives = 100/199 (50%), Gaps = 38/199 (19%)
Query: 510 SISEDEMVLRERSYD----YQFRYCGHCNTTTDIKEANFFGSNAQYIVSGSDDGSFFIWE 565
S +++++ L S+ Y RY GH N T +K NF+G ++++VSGSD G F+WE
Sbjct: 405 SYNDEDIYLFNSSHSDGAQYVKRYKGHRNNAT-VKGVNFYGPKSEFVVSGSDCGHIFLWE 463
Query: 566 KETTNLVRVLQGDE-SIVNCLQPHPSYCFLATSGIDPVVRLWNPRPE-SEDLTGRVVEDM 623
K + +++ ++GD+ +VNCL+PHP LATSG+D V++W P E S +LTG +
Sbjct: 464 KSSCQIIQFMEGDKGGVVNCLEPHPHLPVLATSGLDHDVKIWAPTAEASTELTG-----L 518
Query: 624 EGASQANQRRMNADPLEVMLLNMGYRITGL-------------SSGGAGASD-------- 662
+ + N+R + D L L + + L G GA+D
Sbjct: 519 KDVIKKNKRERDEDSLHQTDLFDSHMLWFLMHHLRQRRHHRRWREPGVGATDADSDESPS 578
Query: 663 -----DEDSSEGQVQCRPS 676
DE+ +VQC PS
Sbjct: 579 SSDTSDEEEGPDRVQCMPS 597
>gi|211904182 DDB1 and CUL4 associated factor 8-like 2 [Homo
sapiens]
Length = 631
Score = 122 bits (306), Expect = 1e-27
Identities = 89/309 (28%), Positives = 136/309 (44%), Gaps = 47/309 (15%)
Query: 33 FIRRLGLEAELQGHSGCVNCLEWNEKGDLLASGSDDQHTIVWDPLHHKKLLSMHTGHTAN 92
F++R L+ L H GCVN + +N++G LAS DD IVWD + + +L+ +GHT N
Sbjct: 214 FVQRFRLQYRLADHVGCVNTVHFNQRGTRLASSGDDLKVIVWDWVRQRPVLNFESGHTNN 273
Query: 93 IFSVKFLPHAGDRILITGAADSKVHVHDL---TVKETIHMFGDHTNRVKRIATAPMWPNT 149
+F KFLP+ GD L A D +V V +L + H ++A P P
Sbjct: 274 VFQAKFLPNCGDSTLAMCARDGQVRVAELINASYFNNTKCVAQHRGPAHKLALEPDSPYK 333
Query: 150 FWSAAEDGLIRQYDLRENSKHSEVLIDLTEYCGQLVEAKCLTVNPQDNNCLAVGASGPFV 209
F ++ ED ++ DLR++ S+V++ T + V +TVNP + AVG FV
Sbjct: 334 FLTSGEDAVVFTIDLRQDRPASKVVV--TRENDKKVGLYTITVNPANTYQFAVGGQDQFV 391
Query: 210 RLYDIRMIHNHRKSMKQSPSAGVHTFCDRQKPLPDGAAQYYVAGHLPVKLPDYNNRLRVL 269
R+YD R I K +G + + HL D+ +
Sbjct: 392 RIYDQRKI---------------------DKKENNGVLKKFTPHHLVNC--DFPTNI--- 425
Query: 270 VATYVTFSPNGTELLVNMGGEQVYLFDLTYKQRPYTFLLPRKCHSSGVQNGKMSTNGVSN 329
T V +S +GTELL + + +YLF+ HS G Q K +N
Sbjct: 426 --TCVVYSHDGTELLASYNDDDIYLFN--------------SSHSDGAQYSKRFKGHRNN 469
Query: 330 GVSNGLHLH 338
G++ +
Sbjct: 470 TTVKGVNFY 478
Score = 87.0 bits (214), Expect = 5e-17
Identities = 45/114 (39%), Positives = 70/114 (61%), Gaps = 7/114 (6%)
Query: 510 SISEDEMVLRERSYD----YQFRYCGHCNTTTDIKEANFFGSNAQYIVSGSDDGSFFIWE 565
S ++D++ L S+ Y R+ GH N TT +K NF+G ++++VSGSD G F WE
Sbjct: 440 SYNDDDIYLFNSSHSDGAQYSKRFKGHRNNTT-VKGVNFYGPRSEFVVSGSDCGHIFFWE 498
Query: 566 KETTNLVRVLQGD-ESIVNCLQPHPSYCFLATSGIDPVVRLWNPRPE-SEDLTG 617
K + +++ L+G E +NCL+PHP LA SG+D V++W P + + +LTG
Sbjct: 499 KSSCQIIQFLKGSREGTINCLEPHPYLPVLACSGLDHDVKIWTPTAKAATELTG 552
>gi|63252910 IQ motif and WD repeats 1 isoform b [Homo sapiens]
Length = 860
Score = 119 bits (297), Expect = 1e-26
Identities = 89/293 (30%), Positives = 134/293 (45%), Gaps = 29/293 (9%)
Query: 9 DLIRRQIKERGALSFERRYHVTDPFIRRLGLEAELQGHSGCVNCLEWNEKGDLLASGSDD 68
D+ +R + RY FI+RL LEA L H GCVN + WN+ G+ + SGSDD
Sbjct: 13 DVRKRSLGLEDPSRLRSRYLGRREFIQRLKLEATLNVHDGCVNTICWNDTGEYILSGSDD 72
Query: 69 QHTIVWDPLHHKKLLSMHTGHTANIFSVKFLPHAGDRILITGAADSKVHVHDLTVKETIH 128
++ +P K L ++ +GH ANIFS KFLP D+ +++ + D + ++ +
Sbjct: 73 TKLVISNPYSRKVLTTIRSGHRANIFSAKFLPCTNDKQIVSCSGDGVIFYTNVEQDAETN 132
Query: 129 ---MFGDHTNRVKRIATAPMWPNTFWSAAEDGLIRQYD--LRENSKHSEVLIDLTEYCGQ 183
F H I T P P TF S EDG +R +D ++ + + D+ C +
Sbjct: 133 RQCQFTCHYGTTYEIMTVPNDPYTFLSCGEDGTVRWFDTRIKTSCTKEDCKDDILINCRR 192
Query: 184 LVEAKCLTVNPQDNNCLAVGASGPFVRLYDIRMIHNHRKSMKQSPSAGVHTFCDRQKPLP 243
A + + P LAVG S VR+YD RM+ + AG T
Sbjct: 193 --AATSVAICPPIPYYLAVGCSDSSVRIYDRRML----GTRATGNYAGRGT--------- 237
Query: 244 DGAAQYYVAGHLPVKLPDYNNRLRVLVATYVTFSPNGTELLVNMGGEQVYLFD 296
G ++ HL N RV T + +S +G E+LV+ + +YLFD
Sbjct: 238 TGMVARFIPSHL------NNKSCRV---TSLCYSEDGQEILVSYSSDYIYLFD 281
Score = 92.8 bits (229), Expect = 9e-19
Identities = 52/150 (34%), Positives = 86/150 (57%), Gaps = 12/150 (8%)
Query: 529 YCGHCNTTTDIKEANFFGSNAQYIVSGSDDGSFFIWEKETTNLVRVLQGDESIVNCLQPH 588
Y GH N+ T IKEANF+G+N +++SGSD G FIW++ T + +L+ D +VNCLQPH
Sbjct: 713 YKGHRNSRTMIKEANFWGAN--FVMSGSDCGHIFIWDRHTAEHLMLLEADNHVVNCLQPH 770
Query: 589 PSYCFLATSGIDPVVRLWNPRPESEDLTGRVVEDMEGASQ------ANQRRMNADPLEVM 642
P LA+SGID +++W+P ES ++ +++ ++ N + A + M
Sbjct: 771 PFDPILASSGIDYDIKIWSPLEESRIFNRKLADEVITRNELMLEETRNTITVPASFMLRM 830
Query: 643 LLNMGY----RITGLSSGGAGASDDEDSSE 668
L ++ + R+ G S G+G ++ + E
Sbjct: 831 LASLNHIRADRLEGDRSEGSGQENENEDEE 860
>gi|63252908 IQ motif and WD repeats 1 isoform a [Homo sapiens]
Length = 880
Score = 119 bits (297), Expect = 1e-26
Identities = 89/293 (30%), Positives = 134/293 (45%), Gaps = 29/293 (9%)
Query: 9 DLIRRQIKERGALSFERRYHVTDPFIRRLGLEAELQGHSGCVNCLEWNEKGDLLASGSDD 68
D+ +R + RY FI+RL LEA L H GCVN + WN+ G+ + SGSDD
Sbjct: 13 DVRKRSLGLEDPSRLRSRYLGRREFIQRLKLEATLNVHDGCVNTICWNDTGEYILSGSDD 72
Query: 69 QHTIVWDPLHHKKLLSMHTGHTANIFSVKFLPHAGDRILITGAADSKVHVHDLTVKETIH 128
++ +P K L ++ +GH ANIFS KFLP D+ +++ + D + ++ +
Sbjct: 73 TKLVISNPYSRKVLTTIRSGHRANIFSAKFLPCTNDKQIVSCSGDGVIFYTNVEQDAETN 132
Query: 129 ---MFGDHTNRVKRIATAPMWPNTFWSAAEDGLIRQYD--LRENSKHSEVLIDLTEYCGQ 183
F H I T P P TF S EDG +R +D ++ + + D+ C +
Sbjct: 133 RQCQFTCHYGTTYEIMTVPNDPYTFLSCGEDGTVRWFDTRIKTSCTKEDCKDDILINCRR 192
Query: 184 LVEAKCLTVNPQDNNCLAVGASGPFVRLYDIRMIHNHRKSMKQSPSAGVHTFCDRQKPLP 243
A + + P LAVG S VR+YD RM+ + AG T
Sbjct: 193 --AATSVAICPPIPYYLAVGCSDSSVRIYDRRML----GTRATGNYAGRGT--------- 237
Query: 244 DGAAQYYVAGHLPVKLPDYNNRLRVLVATYVTFSPNGTELLVNMGGEQVYLFD 296
G ++ HL N RV T + +S +G E+LV+ + +YLFD
Sbjct: 238 TGMVARFIPSHL------NNKSCRV---TSLCYSEDGQEILVSYSSDYIYLFD 281
Score = 92.8 bits (229), Expect = 9e-19
Identities = 52/150 (34%), Positives = 86/150 (57%), Gaps = 12/150 (8%)
Query: 529 YCGHCNTTTDIKEANFFGSNAQYIVSGSDDGSFFIWEKETTNLVRVLQGDESIVNCLQPH 588
Y GH N+ T IKEANF+G+N +++SGSD G FIW++ T + +L+ D +VNCLQPH
Sbjct: 733 YKGHRNSRTMIKEANFWGAN--FVMSGSDCGHIFIWDRHTAEHLMLLEADNHVVNCLQPH 790
Query: 589 PSYCFLATSGIDPVVRLWNPRPESEDLTGRVVEDMEGASQ------ANQRRMNADPLEVM 642
P LA+SGID +++W+P ES ++ +++ ++ N + A + M
Sbjct: 791 PFDPILASSGIDYDIKIWSPLEESRIFNRKLADEVITRNELMLEETRNTITVPASFMLRM 850
Query: 643 LLNMGY----RITGLSSGGAGASDDEDSSE 668
L ++ + R+ G S G+G ++ + E
Sbjct: 851 LASLNHIRADRLEGDRSEGSGQENENEDEE 880
>gi|62988359 DDB1 and CUL4 associated factor 8-like 1 [Homo sapiens]
Length = 600
Score = 107 bits (268), Expect = 3e-23
Identities = 77/267 (28%), Positives = 121/267 (45%), Gaps = 33/267 (12%)
Query: 33 FIRRLGLEAELQGHSGCVNCLEWNEKGDLLASGSDDQHTIVWDPLHHKKLLSMHTGHTAN 92
F++R L+ L H+G V+ + +N++G LAS DD IVWD + K +L+ +GH N
Sbjct: 182 FVQRFRLQYLLGSHAGSVSTIHFNQRGTRLASSGDDLRVIVWDWVRQKPVLNFESGHDIN 241
Query: 93 IFSVKFLPHAGDRILITGAADSKVHVHDL---TVKETIHMFGDHTNRVKRIATAPMWPNT 149
+ KF P+ GD L D +V V +L + E H +A P P
Sbjct: 242 VIQAKFFPNCGDSTLAMCGHDGQVRVAELINASYCENTKRVAKHRGPAHELALEPDSPYK 301
Query: 150 FWSAAEDGLIRQYDLRENSKHSEVLIDLTEYCGQLVEAKCLTVNPQDNNCLAVGASGPFV 209
F ++ ED ++ DLR++ S+V++ T + V +++NP + AVG FV
Sbjct: 302 FLTSGEDAVVFTIDLRQDRPASKVVV--TRENDKKVGLYTISMNPANIYQFAVGGHDQFV 359
Query: 210 RLYDIRMIHNHRKSMKQSPSAGVHTFCDRQKPLPDGAAQYYVAGHLPVKLPDYNNRLRVL 269
R+YD R I K +G + + HL D+ +
Sbjct: 360 RIYDQRRI---------------------DKKENNGVLKKFTPHHL--VYCDFPTNI--- 393
Query: 270 VATYVTFSPNGTELLVNMGGEQVYLFD 296
T V +S +GTELL + E +YLF+
Sbjct: 394 --TCVVYSHDGTELLASYNDEDIYLFN 418
Score = 92.0 bits (227), Expect = 2e-18
Identities = 70/233 (30%), Positives = 108/233 (46%), Gaps = 38/233 (16%)
Query: 467 HSSACDALGRDITAALFSKNDGEEKKGPGGGAPVRLRSTSRKDSISEDEMVLRERSYDYQ 526
H CD +IT ++S +DG E + L ++S D Y
Sbjct: 383 HLVYCD-FPTNITCVVYS-HDGTELLASYNDEDIYLFNSSLSDGAQ------------YV 428
Query: 527 FRYCGHCNTTTDIKEANFFGSNAQYIVSGSDDGSFFIWEKETTNLVRVLQGDE-SIVNCL 585
RY GH N T IK NF+G ++++VSGSD G F WEK ++ +++ ++GD IVNCL
Sbjct: 429 KRYKGHRNNDT-IKCVNFYGPRSEFVVSGSDCGHVFFWEKSSSQIIQFMEGDRGDIVNCL 487
Query: 586 QPHPSYCFLATSGIDPVVRLWNPRPE-SEDLTGRVVEDMEGASQANQRRMN-ADPLEVML 643
+PHP LATSG+D VR+W P + + +LTG + + ++ +N D + +
Sbjct: 488 EPHPYLPVLATSGLDQHVRIWTPTAKTATELTGLKDVIKKNKQERDEDNLNYTDSFDNRM 547
Query: 644 LNM------------GYRITG--------LSSGGAGASDDEDSSEGQVQCRPS 676
L G+R G L + + E+ + +VQC PS
Sbjct: 548 LRFFVRHLLQRAHQPGWRDHGAEFPDEEELDESSSTSDTSEEEGQDRVQCIPS 600
>gi|55741849 WD repeat domain 22 [Homo sapiens]
Length = 942
Score = 80.9 bits (198), Expect = 4e-15
Identities = 58/179 (32%), Positives = 94/179 (52%), Gaps = 13/179 (7%)
Query: 42 ELQGHSGCVNCLEW-NEKGDLLASGSDDQHTIVW---DPLHHK-KLLSMHTGHTANIFSV 96
+L GH GCVN +E+ N G L SG DD+ ++W +H + K + + H +NIF +
Sbjct: 48 DLLGHFGCVNAIEFSNNGGQWLVSGGDDRRVLLWHMEQAIHSRVKPIQLKGEHHSNIFCL 107
Query: 97 KFLPHAGDRILITGAADSKVHVHDLTVKETIHMFGDHTNRVKRIATAPMWPNTFWSAAED 156
F ++G+ + +G D +V +HD+ ET+ +F H + V ++ +P+ N F S+++D
Sbjct: 108 AF--NSGNTKVFSGGNDEQVILHDVESSETLDVFA-HEDAVYGLSVSPVNDNIFASSSDD 164
Query: 157 GLIRQYDLRENSKHSEVLIDLTEYCGQLVEAKCLTVNPQDNNCLAVGASGPFVRLYDIR 215
G + +D+RE S H E L Y + NP + LA S V L+DIR
Sbjct: 165 GRVLIWDIRE-SPHGEPFC-LANYPSAF---HSVMFNPVEPRLLATANSKEGVGLWDIR 218
Score = 60.1 bits (144), Expect = 7e-09
Identities = 43/153 (28%), Positives = 74/153 (48%), Gaps = 26/153 (16%)
Query: 495 GGGAPVRLRSTSRKDSISEDEMVLRERS----YD-------YQFRYCGHCNTTTDIKEAN 543
GG ++ + R +S + LR R YD +QF G+ N+ T +K
Sbjct: 228 GGNLSLQSAMSVRFNSNGTQLLALRRRLPPVLYDIHSRLPVFQFDNQGYFNSCT-MKSCC 286
Query: 544 FFGSNAQYIVSGSDDGSFFIWE-----------KETTNLVRVLQGDESIVNCLQPHPSYC 592
F G QYI+SGSDD + ++W + VL+G SIVN ++ +P
Sbjct: 287 FAGDRDQYILSGSDDFNLYMWRIPADPEAGGIGRVVNGAFMVLKGHRSIVNQVRFNPHTY 346
Query: 593 FLATSGIDPVVRLWNPRPE---SEDLTGRVVED 622
+ +SG++ ++++W+P + + DL GR+ +D
Sbjct: 347 MICSSGVEKIIKIWSPYKQPGCTGDLDGRIEDD 379
>gi|56181387 STIP1 homology and U-box containing protein 1 [Homo
sapiens]
Length = 303
Score = 65.9 bits (159), Expect = 1e-10
Identities = 42/127 (33%), Positives = 64/127 (50%), Gaps = 8/127 (6%)
Query: 356 ELPPYLERVKQQANEAFACQQWTQAIQLYSKAVQRAPHNAMLYGNRAAAYMKRKWDGDHY 415
E P + +K+Q N F +++ +A Y +A+ R P A+ Y NRA Y+K + H
Sbjct: 21 EKSPSAQELKEQGNRLFVGRKYPEAAACYGRAITRNPLVAVYYTNRALCYLKMQ---QHE 77
Query: 416 DALRDCLKAISLNPCHLKAHFRLARCLFELKYVAEALECLDDFKGKFPEQAHSSACDALG 475
AL DC +A+ L+ +KAHF L +C E++ EA+ L EQ + G
Sbjct: 78 QALADCRRALELDGQSVKAHFFLGQCQLEMESYDEAIANLQRAYSLAKEQRLN-----FG 132
Query: 476 RDITAAL 482
DI +AL
Sbjct: 133 DDIPSAL 139
>gi|4506921 small glutamine-rich tetratricopeptide [Homo sapiens]
Length = 313
Score = 63.5 bits (153), Expect = 6e-10
Identities = 38/117 (32%), Positives = 61/117 (52%), Gaps = 6/117 (5%)
Query: 339 SNGFRLPE---SRGHVSPQVELPPYLERVKQQANEAFACQQWTQAIQLYSKAVQRAPHNA 395
+ G +P+ S P E ER+K + NE + + A+ Y KA++ P NA
Sbjct: 66 ATGKEMPQDLRSPARTPPSEEDSAEAERLKTEGNEQMKVENFEAAVHFYGKAIELNPANA 125
Query: 396 MLYGNRAAAYMKRKWDGDHYDALRDCLKAISLNPCHLKAHFRLARCLFELKYVAEAL 452
+ + NRAAAY K G++ A++DC +AI ++P + KA+ R+ L L EA+
Sbjct: 126 VYFCNRAAAYSKL---GNYAGAVQDCERAICIDPAYSKAYGRMGLALSSLNKHVEAV 179
>gi|207029439 retinoblastoma binding protein 4 isoform c [Homo
sapiens]
Length = 390
Score = 58.9 bits (141), Expect = 1e-08
Identities = 39/145 (26%), Positives = 68/145 (46%), Gaps = 16/145 (11%)
Query: 43 LQGHSGCVNCLEWNEKGD-LLASGSDDQHTIVWDPLHHKKLLSMHTGHTANIFSVKFLPH 101
+ H+ VNCL +N + +LA+GS D+ +WD + K L H IF V++ PH
Sbjct: 234 VDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPH 293
Query: 102 AGDRILITGAADSKVHVHDLT--------------VKETIHMFGDHTNRVKRIATAPMWP 147
+ IL + D +++V DL+ E + + G HT ++ + P P
Sbjct: 294 -NETILASSGTDRRLNVWDLSKIGEEQSPEDAEDGPPELLFIHGGHTAKISDFSWNPNEP 352
Query: 148 NTFWSAAEDGLIRQYDLRENSKHSE 172
S +ED +++ + + EN + E
Sbjct: 353 WVICSVSEDNIMQVWQMAENIYNDE 377
Score = 51.6 bits (122), Expect = 2e-06
Identities = 35/124 (28%), Positives = 61/124 (49%), Gaps = 5/124 (4%)
Query: 45 GHSGCVNCLEWNEKGD-LLASGSDDQHTIVWDPLHHKKLLSMHT--GHTANIFSVKFLPH 101
GH+ V + W+ + L S +DDQ ++WD + H+ HTA + + F P+
Sbjct: 190 GHTAVVEDVSWHLLHESLFGSVADDQKLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPY 249
Query: 102 AGDRILITGAADSKVHVHDL-TVKETIHMFGDHTNRVKRIATAPMWPNTFWSAAEDGLIR 160
+ + IL TG+AD V + DL +K +H F H + + ++ +P S+ D +
Sbjct: 250 S-EFILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLN 308
Query: 161 QYDL 164
+DL
Sbjct: 309 VWDL 312
Score = 40.4 bits (93), Expect = 0.005
Identities = 38/144 (26%), Positives = 60/144 (41%), Gaps = 26/144 (18%)
Query: 74 WDPLHHKKLLSMHTGHTANIFSVKFLPHAGDRILITGAADSKVHVHDLTVKETIHMFGDH 133
W+P LLS HT ++ + +P G + D+K +F H
Sbjct: 150 WNPNLSGHLLSASDDHTICLWDISAVPKEGKVV------DAKT------------IFTGH 191
Query: 134 TNRVKRIATAPMWPNTFWSAAEDGLIRQYDLREN--SKHSEVLIDLTEYCGQLVEAKCLT 191
T V+ ++ + + F S A+D + +D R N SK S + T E CL+
Sbjct: 192 TAVVEDVSWHLLHESLFGSVADDQKLMIWDTRSNNTSKPSHSVDAHT------AEVNCLS 245
Query: 192 VNPQDNNCLAVGASGPFVRLYDIR 215
NP LA G++ V L+D+R
Sbjct: 246 FNPYSEFILATGSADKTVALWDLR 269
>gi|207029415 retinoblastoma binding protein 4 isoform b [Homo
sapiens]
Length = 424
Score = 58.9 bits (141), Expect = 1e-08
Identities = 39/145 (26%), Positives = 68/145 (46%), Gaps = 16/145 (11%)
Query: 43 LQGHSGCVNCLEWNEKGD-LLASGSDDQHTIVWDPLHHKKLLSMHTGHTANIFSVKFLPH 101
+ H+ VNCL +N + +LA+GS D+ +WD + K L H IF V++ PH
Sbjct: 268 VDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPH 327
Query: 102 AGDRILITGAADSKVHVHDLT--------------VKETIHMFGDHTNRVKRIATAPMWP 147
+ IL + D +++V DL+ E + + G HT ++ + P P
Sbjct: 328 -NETILASSGTDRRLNVWDLSKIGEEQSPEDAEDGPPELLFIHGGHTAKISDFSWNPNEP 386
Query: 148 NTFWSAAEDGLIRQYDLRENSKHSE 172
S +ED +++ + + EN + E
Sbjct: 387 WVICSVSEDNIMQVWQMAENIYNDE 411
Score = 51.6 bits (122), Expect = 2e-06
Identities = 35/124 (28%), Positives = 61/124 (49%), Gaps = 5/124 (4%)
Query: 45 GHSGCVNCLEWNEKGD-LLASGSDDQHTIVWDPLHHKKLLSMHT--GHTANIFSVKFLPH 101
GH+ V + W+ + L S +DDQ ++WD + H+ HTA + + F P+
Sbjct: 224 GHTAVVEDVSWHLLHESLFGSVADDQKLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPY 283
Query: 102 AGDRILITGAADSKVHVHDL-TVKETIHMFGDHTNRVKRIATAPMWPNTFWSAAEDGLIR 160
+ + IL TG+AD V + DL +K +H F H + + ++ +P S+ D +
Sbjct: 284 S-EFILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLN 342
Query: 161 QYDL 164
+DL
Sbjct: 343 VWDL 346
Score = 40.4 bits (93), Expect = 0.005
Identities = 38/144 (26%), Positives = 60/144 (41%), Gaps = 26/144 (18%)
Query: 74 WDPLHHKKLLSMHTGHTANIFSVKFLPHAGDRILITGAADSKVHVHDLTVKETIHMFGDH 133
W+P LLS HT ++ + +P G + D+K +F H
Sbjct: 184 WNPNLSGHLLSASDDHTICLWDISAVPKEGKVV------DAKT------------IFTGH 225
Query: 134 TNRVKRIATAPMWPNTFWSAAEDGLIRQYDLREN--SKHSEVLIDLTEYCGQLVEAKCLT 191
T V+ ++ + + F S A+D + +D R N SK S + T E CL+
Sbjct: 226 TAVVEDVSWHLLHESLFGSVADDQKLMIWDTRSNNTSKPSHSVDAHT------AEVNCLS 279
Query: 192 VNPQDNNCLAVGASGPFVRLYDIR 215
NP LA G++ V L+D+R
Sbjct: 280 FNPYSEFILATGSADKTVALWDLR 303
>gi|5032027 retinoblastoma binding protein 4 isoform a [Homo
sapiens]
Length = 425
Score = 58.9 bits (141), Expect = 1e-08
Identities = 39/145 (26%), Positives = 68/145 (46%), Gaps = 16/145 (11%)
Query: 43 LQGHSGCVNCLEWNEKGD-LLASGSDDQHTIVWDPLHHKKLLSMHTGHTANIFSVKFLPH 101
+ H+ VNCL +N + +LA+GS D+ +WD + K L H IF V++ PH
Sbjct: 269 VDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPH 328
Query: 102 AGDRILITGAADSKVHVHDLT--------------VKETIHMFGDHTNRVKRIATAPMWP 147
+ IL + D +++V DL+ E + + G HT ++ + P P
Sbjct: 329 -NETILASSGTDRRLNVWDLSKIGEEQSPEDAEDGPPELLFIHGGHTAKISDFSWNPNEP 387
Query: 148 NTFWSAAEDGLIRQYDLRENSKHSE 172
S +ED +++ + + EN + E
Sbjct: 388 WVICSVSEDNIMQVWQMAENIYNDE 412
Score = 51.6 bits (122), Expect = 2e-06
Identities = 35/124 (28%), Positives = 61/124 (49%), Gaps = 5/124 (4%)
Query: 45 GHSGCVNCLEWNEKGD-LLASGSDDQHTIVWDPLHHKKLLSMHT--GHTANIFSVKFLPH 101
GH+ V + W+ + L S +DDQ ++WD + H+ HTA + + F P+
Sbjct: 225 GHTAVVEDVSWHLLHESLFGSVADDQKLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPY 284
Query: 102 AGDRILITGAADSKVHVHDL-TVKETIHMFGDHTNRVKRIATAPMWPNTFWSAAEDGLIR 160
+ + IL TG+AD V + DL +K +H F H + + ++ +P S+ D +
Sbjct: 285 S-EFILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLN 343
Query: 161 QYDL 164
+DL
Sbjct: 344 VWDL 347
Score = 40.4 bits (93), Expect = 0.005
Identities = 38/144 (26%), Positives = 60/144 (41%), Gaps = 26/144 (18%)
Query: 74 WDPLHHKKLLSMHTGHTANIFSVKFLPHAGDRILITGAADSKVHVHDLTVKETIHMFGDH 133
W+P LLS HT ++ + +P G + D+K +F H
Sbjct: 185 WNPNLSGHLLSASDDHTICLWDISAVPKEGKVV------DAKT------------IFTGH 226
Query: 134 TNRVKRIATAPMWPNTFWSAAEDGLIRQYDLREN--SKHSEVLIDLTEYCGQLVEAKCLT 191
T V+ ++ + + F S A+D + +D R N SK S + T E CL+
Sbjct: 227 TAVVEDVSWHLLHESLFGSVADDQKLMIWDTRSNNTSKPSHSVDAHT------AEVNCLS 280
Query: 192 VNPQDNNCLAVGASGPFVRLYDIR 215
NP LA G++ V L+D+R
Sbjct: 281 FNPYSEFILATGSADKTVALWDLR 304
>gi|19913371 transducin (beta)-like 1 X-linked receptor 1 [Homo
sapiens]
Length = 514
Score = 58.9 bits (141), Expect = 1e-08
Identities = 60/246 (24%), Positives = 101/246 (41%), Gaps = 34/246 (13%)
Query: 39 LEAELQGHSGCVNCLEWNEKGDLLASGSDDQHTIVWDPLHHKKLLSMHTGHTANIFSVKF 98
L + L H G + L+WN+KG+ + S D+ TI+WD H + H+A V +
Sbjct: 258 LASTLGQHKGPIFALKWNKKGNFILSAGVDKTTIIWD-AHTGEAKQQFPFHSAPALDVDW 316
Query: 99 LPHAGDRILITGAADSKVHVHDLTVKETIHMFGDHTNRVKRIATAPMWPNTFWSAAEDGL 158
+ + + D +HV L I F HTN V I P N S ++D
Sbjct: 317 ---QSNNTFASCSTDMCIHVCKLGQDRPIKTFQGHTNEVNAIKWDPT-GNLLASCSDDMT 372
Query: 159 IRQYDLRENSKHSEVLIDLTEYCGQLVEAKCL-----TVNPQDNNCLAVGASGPFVRLYD 213
++ + +++++ + DL + ++ K T NP N LA + VRL+D
Sbjct: 373 LKIWSMKQDN----CVHDLQAHNKEIYTIKWSPTGPGTNNPNANLMLASASFDSTVRLWD 428
Query: 214 IRMIHNHRKSMKQSPSAGVHTFCDRQKPL------PDGAAQYYVAGHLPVKLPDYNNRLR 267
+ +HT Q+P+ PDG +Y +G + +N +
Sbjct: 429 V------------DRGICIHTLTKHQEPVYSVAFSPDG--RYLASGSFDKCVHIWNTQTG 474
Query: 268 VLVATY 273
LV +Y
Sbjct: 475 ALVHSY 480
Score = 33.1 bits (74), Expect = 0.86
Identities = 15/33 (45%), Positives = 18/33 (54%)
Query: 43 LQGHSGCVNCLEWNEKGDLLASGSDDQHTIVWD 75
L+GH V WN DLLASGS D +W+
Sbjct: 165 LRGHESEVFICAWNPVSDLLASGSGDSTARIWN 197
Score = 32.0 bits (71), Expect = 1.9
Identities = 38/148 (25%), Positives = 60/148 (40%), Gaps = 19/148 (12%)
Query: 475 GRDITAALFSKNDGEEKKG-PGGGAP---VRLRSTSRKDSISEDEMV-LRERSYDYQFR- 528
G D T ++ + GE K+ P AP V +S + S S D + + + D +
Sbjct: 285 GVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQSNNTFASCSTDMCIHVCKLGQDRPIKT 344
Query: 529 YCGHCNTTTDIKEANFFGSNAQYIVSGSDDGSFFIWEKETTNLVRVLQGDESIVNCLQPH 588
+ GH N IK + + S SDD + IW + N V LQ + ++
Sbjct: 345 FQGHTNEVNAIK----WDPTGNLLASCSDDMTLKIWSMKQDNCVHDLQAHNKEIYTIKWS 400
Query: 589 P---------SYCFLATSGIDPVVRLWN 607
P + LA++ D VRLW+
Sbjct: 401 PTGPGTNNPNANLMLASASFDSTVRLWD 428
>gi|5453958 protein phosphatase 5, catalytic subunit [Homo sapiens]
Length = 499
Score = 58.5 bits (140), Expect = 2e-08
Identities = 30/78 (38%), Positives = 49/78 (62%), Gaps = 3/78 (3%)
Query: 362 ERVKQQANEAFACQQWTQAIQLYSKAVQRAPHNAMLYGNRAAAYMKRKWDGDHYDALRDC 421
E +K QAN+ F + + AI+ YS+A++ P NA+ YGNR+ AY++ + G AL D
Sbjct: 29 EELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYG---YALGDA 85
Query: 422 LKAISLNPCHLKAHFRLA 439
+AI L+ ++K ++R A
Sbjct: 86 TRAIELDKKYIKGYYRRA 103
>gi|5902034 periodic tryptophan protein 1 [Homo sapiens]
Length = 501
Score = 58.5 bits (140), Expect = 2e-08
Identities = 43/172 (25%), Positives = 79/172 (45%), Gaps = 10/172 (5%)
Query: 44 QGHSGCVNCLEWNEK-GDLLASGSDDQHTIVWDPLHHKKLLSMHTGHTANIFSVKFLPHA 102
+GH+ V L WN+ ++LAS S D I+WD K S+ HT + +++F P
Sbjct: 253 EGHTDAVLDLSWNKLIRNVLASASADNTVILWDMSLGKPAASLAV-HTDKVQTLQFHPFE 311
Query: 103 GDRILITGAADSKVHVHDLTVKETIHMFGDHTNRVKRIATAPMWPNTFWSAAEDGLIRQY 162
+ LI+G+ D V ++D + H + +++R+ P F ++ +DG +
Sbjct: 312 A-QTLISGSYDKSVALYDCRSPDESHRMWRFSGQIERVTWNHFSPCHFLASTDDGFVYNL 370
Query: 163 DLRENSKHSEVLIDLTEYCGQLVEAKCLTVNPQDNNCLAVGASGPFVRLYDI 214
D R + + E G L ++ Q CL ++ +V+++DI
Sbjct: 371 DARSDKPIFTLNAHNDEISG-------LDLSSQIKGCLVTASADKYVKIWDI 415
>gi|4506439 retinoblastoma binding protein 7 [Homo sapiens]
Length = 425
Score = 57.8 bits (138), Expect = 3e-08
Identities = 39/145 (26%), Positives = 67/145 (46%), Gaps = 16/145 (11%)
Query: 43 LQGHSGCVNCLEWNEKGD-LLASGSDDQHTIVWDPLHHKKLLSMHTGHTANIFSVKFLPH 101
+ H+ VNCL +N + +LA+GS D+ +WD + K L H IF V + PH
Sbjct: 268 VDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHTFESHKDEIFQVHWSPH 327
Query: 102 AGDRILITGAADSKVHVHDLT--------------VKETIHMFGDHTNRVKRIATAPMWP 147
+ IL + D +++V DL+ E + + G HT ++ + P P
Sbjct: 328 -NETILASSGTDRRLNVWDLSKIGEEQSAEDAEDGPPELLFIHGGHTAKISDFSWNPNEP 386
Query: 148 NTFWSAAEDGLIRQYDLRENSKHSE 172
S +ED +++ + + EN + E
Sbjct: 387 WVICSVSEDNIMQIWQMAENIYNDE 411
Score = 51.2 bits (121), Expect = 3e-06
Identities = 37/129 (28%), Positives = 62/129 (48%), Gaps = 5/129 (3%)
Query: 40 EAELQGHSGCVNCLEWNEKGD-LLASGSDDQHTIVWDPLHHKKLLSMH--TGHTANIFSV 96
+A GHS V + W+ + L S +DDQ ++WD + H HTA + +
Sbjct: 219 KAIFTGHSAVVEDVAWHLLHESLFGSVADDQKLMIWDTRSNTTSKPSHLVDAHTAEVNCL 278
Query: 97 KFLPHAGDRILITGAADSKVHVHDL-TVKETIHMFGDHTNRVKRIATAPMWPNTFWSAAE 155
F P++ + IL TG+AD V + DL +K +H F H + + ++ +P S+
Sbjct: 279 SFNPYS-EFILATGSADKTVALWDLRNLKLKLHTFESHKDEIFQVHWSPHNETILASSGT 337
Query: 156 DGLIRQYDL 164
D + +DL
Sbjct: 338 DRRLNVWDL 346
Score = 37.4 bits (85), Expect = 0.046
Identities = 38/144 (26%), Positives = 59/144 (40%), Gaps = 26/144 (18%)
Query: 74 WDPLHHKKLLSMHTGHTANIFSVKFLPHAGDRILITGAADSKVHVHDLTVKETIHMFGDH 133
W+ LLS HT ++ + P G + D+K +F H
Sbjct: 184 WNSNLSGHLLSASDDHTVCLWDINAGPKEGKIV------DAKA------------IFTGH 225
Query: 134 TNRVKRIATAPMWPNTFWSAAEDGLIRQYDLREN--SKHSEVLIDLTEYCGQLVEAKCLT 191
+ V+ +A + + F S A+D + +D R N SK S L+D E CL+
Sbjct: 226 SAVVEDVAWHLLHESLFGSVADDQKLMIWDTRSNTTSKPSH-LVD-----AHTAEVNCLS 279
Query: 192 VNPQDNNCLAVGASGPFVRLYDIR 215
NP LA G++ V L+D+R
Sbjct: 280 FNPYSEFILATGSADKTVALWDLR 303
>gi|5803181 stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizing
protein) [Homo sapiens]
Length = 543
Score = 57.4 bits (137), Expect = 4e-08
Identities = 35/108 (32%), Positives = 57/108 (52%), Gaps = 8/108 (7%)
Query: 346 ESRGHVSPQVELPPYLERVKQQANEAFACQQWTQAIQLYSKAVQRAPHNAMLYGNRAAAY 405
E +++P + L K + NE F + QA++ Y++A++R P +A LY NRAA Y
Sbjct: 350 ERLAYINPDLALEE-----KNKGNECFQKGDYPQAMKHYTEAIKRNPKDAKLYSNRAACY 404
Query: 406 MKRKWDGDHYDALRDCLKAISLNPCHLKAHFRLARCLFELKYVAEALE 453
K + AL+DC + I L P +K + R A L +K +A++
Sbjct: 405 TKLL---EFQLALKDCEECIQLEPTFIKGYTRKAAALEAMKDYTKAMD 449
Score = 57.0 bits (136), Expect = 6e-08
Identities = 33/91 (36%), Positives = 49/91 (53%), Gaps = 3/91 (3%)
Query: 361 LERVKQQANEAFACQQWTQAIQLYSKAVQRAPHNAMLYGNRAAAYMKRKWDGDHYDALRD 420
+ +K++ N+A + A+Q YS+A++ PHN +LY NR+AAY K+ GD+ A D
Sbjct: 4 VNELKEKGNKALSVGNIDDALQCYSEAIKLDPHNHVLYSNRSAAYAKK---GDYQKAYED 60
Query: 421 CLKAISLNPCHLKAHFRLARCLFELKYVAEA 451
K + L P K + R A L L EA
Sbjct: 61 GCKTVDLKPDWGKGYSRKAAALEFLNRFEEA 91
Score = 32.7 bits (73), Expect = 1.1
Identities = 19/63 (30%), Positives = 32/63 (50%), Gaps = 3/63 (4%)
Query: 365 KQQANEAFACQQWTQAIQLYSKAVQRAPHNAMLYGNRAAAYMKRKWDGDHYDALRDCLKA 424
K+ N+A+ + + A++ Y KA + P N N+AA Y ++ GD+ C KA
Sbjct: 229 KELGNDAYKKKDFDTALKHYDKAKELDPTNMTYITNQAAVYFEK---GDYNKCRELCEKA 285
Query: 425 ISL 427
I +
Sbjct: 286 IEV 288
>gi|83779014 katanin p80 subunit B 1 [Homo sapiens]
Length = 655
Score = 57.4 bits (137), Expect = 4e-08
Identities = 45/174 (25%), Positives = 80/174 (45%), Gaps = 16/174 (9%)
Query: 43 LQGHSGCVNCLEWNEKGDLLASGSDDQHTIVWDPLHHKKLLSMHTGHTANIFSVKFLPHA 102
L GH+ V + N +L+ +GS VWD L K+L GH ANI S+ F P+
Sbjct: 59 LTGHTSPVESVRLNTPEELIVAGSQSGSIRVWD-LEAAKILRTLMGHKANICSLDFHPYG 117
Query: 103 GDRILITGAADSKVHVHDLTVKETIHMFGDHTNRVKRIATAP--MWPNTFWSAAEDGLIR 160
+ +G+ D+ + + D+ K + + H+ V+ + +P W SAA+D ++
Sbjct: 118 --EFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKW---LASAADDHTVK 172
Query: 161 QYDLRENSKHSEVLIDLTEYCGQLVEAKCLTVNPQDNNCLAVGASGPFVRLYDI 214
+DL ++E+ G + +P + LA G+S +R +D+
Sbjct: 173 LWDLTAGKM-------MSEFPGHTGPVNVVEFHPNE-YLLASGSSDRTIRFWDL 218
Score = 55.1 bits (131), Expect = 2e-07
Identities = 34/111 (30%), Positives = 53/111 (47%), Gaps = 3/111 (2%)
Query: 34 IRRLGLEAELQGHSGCVNCLEWNEKGDLLASGSDDQHTIVWDPLHHKKLLSMHTGHTANI 93
IRR G +GHS V CL ++ G LAS +DD +WD L K++S GHT +
Sbjct: 134 IRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWD-LTAGKMMSEFPGHTGPV 192
Query: 94 FSVKFLPHAGDRILITGAADSKVHVHDLTVKETIHMFGDHTNRVKRIATAP 144
V+F H + +L +G++D + DL + + V+ + P
Sbjct: 193 NVVEF--HPNEYLLASGSSDRTIRFWDLEKFQVVSCIEGEPGPVRSVLFNP 241
Score = 50.1 bits (118), Expect = 7e-06
Identities = 36/126 (28%), Positives = 60/126 (47%), Gaps = 8/126 (6%)
Query: 43 LQGHSGCVNCLEWNEKGDLLASGSDDQHTIVWDPLHHKKLLSMHTGHTANIFSVKFLPHA 102
L GH + L+++ G+ +ASGS D + +WD + K + + GH+ + ++F P
Sbjct: 101 LMGHKANICSLDFHPYGEFVASGSQDTNIKLWD-IRRKGCVFRYRGHSQAVRCLRFSPDG 159
Query: 103 GDRILITGAADSKVHVHDLTVKETIHMFGDHTNRVKRIATAPMWPNTFW--SAAEDGLIR 160
+ L + A D V + DLT + + F HT V PN + S + D IR
Sbjct: 160 --KWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVN---VVEFHPNEYLLASGSSDRTIR 214
Query: 161 QYDLRE 166
+DL +
Sbjct: 215 FWDLEK 220
Score = 47.8 bits (112), Expect = 3e-05
Identities = 42/174 (24%), Positives = 77/174 (44%), Gaps = 13/174 (7%)
Query: 42 ELQGHSGCVNCLEWNE-KGDLLASGSDDQHTIVWDPLHHKKLLSMHTGHTANIFSVKFLP 100
E+ H+ V+ L + G LLA+G DD +W ++S+ TGHT+ + SV+
Sbjct: 15 EIVAHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCIMSL-TGHTSPVESVRL-- 71
Query: 101 HAGDRILITGAADSKVHVHDLTVKETIHMFGDHTNRVKRIATAPMWPNTFWSAAEDGLIR 160
+ + +++ G+ + V DL + + H + + P + S ++D I+
Sbjct: 72 NTPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHP-YGEFVASGSQDTNIK 130
Query: 161 QYDLRENSKHSEVLIDLTEYCGQLVEAKCLTVNPQDNNCLAVGASGPFVRLYDI 214
+D+R + Y G +CL +P D LA A V+L+D+
Sbjct: 131 LWDIRRKG-------CVFRYRGHSQAVRCLRFSP-DGKWLASAADDHTVKLWDL 176
Score = 43.5 bits (101), Expect = 6e-04
Identities = 20/60 (33%), Positives = 34/60 (56%)
Query: 550 QYIVSGSDDGSFFIWEKETTNLVRVLQGDESIVNCLQPHPSYCFLATSGIDPVVRLWNPR 609
+ IV+GS GS +W+ E ++R L G ++ + L HP F+A+ D ++LW+ R
Sbjct: 76 ELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIR 135
Score = 42.0 bits (97), Expect = 0.002
Identities = 20/81 (24%), Positives = 38/81 (46%), Gaps = 4/81 (4%)
Query: 527 FRYCGHCNTTTDIKEANFFGSNAQYIVSGSDDGSFFIWEKETTNLVRVLQGDESIVNCLQ 586
FRY GH ++ F + +++ S +DD + +W+ ++ G VN ++
Sbjct: 141 FRYRGHSQAVRCLR----FSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVE 196
Query: 587 PHPSYCFLATSGIDPVVRLWN 607
HP+ LA+ D +R W+
Sbjct: 197 FHPNEYLLASGSSDRTIRFWD 217
Score = 37.4 bits (85), Expect = 0.046
Identities = 23/82 (28%), Positives = 39/82 (47%), Gaps = 8/82 (9%)
Query: 545 FGSNAQYIVSGSDDGSFFIWEKETTNLVRVLQGDESIVNCLQPHPSYCFLATSGIDPVVR 604
F +++ SGS D + +W+ V +G V CL+ P +LA++ D V+
Sbjct: 113 FHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVK 172
Query: 605 LWNPRPESEDLT-GRVVEDMEG 625
LW DLT G+++ + G
Sbjct: 173 LW-------DLTAGKMMSEFPG 187
Score = 32.0 bits (71), Expect = 1.9
Identities = 19/67 (28%), Positives = 31/67 (46%), Gaps = 1/67 (1%)
Query: 545 FGSNAQYIVSGSDDGSFFIWEKETTNLVRVLQGDESIVNCLQPHPSYCFLATSGIDPVVR 604
F N + SGS D + W+ E +V ++G+ V + +P C L SG +R
Sbjct: 197 FHPNEYLLASGSSDRTIRFWDLEKFQVVSCIEGEPGPVRSVLFNPDGCCL-YSGCQDSLR 255
Query: 605 LWNPRPE 611
++ PE
Sbjct: 256 VYGWEPE 262
Score = 29.6 bits (65), Expect = 9.5
Identities = 32/128 (25%), Positives = 53/128 (41%), Gaps = 12/128 (9%)
Query: 89 HTANIFSVKFLPHAGDRILITGAADSKVHVHDLTVKETIHMFGDHTNRVKRI-ATAPMWP 147
H +N+ S+ L A R+L TG D +V++ + I HT+ V+ + P
Sbjct: 19 HASNVSSL-VLGKASGRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTP--E 75
Query: 148 NTFWSAAEDGLIRQYDLRENSKHSEVLIDLTEYCGQLVEAKCLTVNPQDNNCLAVGASGP 207
+ ++ G IR +DL E L G L +P +A G+
Sbjct: 76 ELIVAGSQSGSIRVWDL-------EAAKILRTLMGHKANICSLDFHPY-GEFVASGSQDT 127
Query: 208 FVRLYDIR 215
++L+DIR
Sbjct: 128 NIKLWDIR 135
>gi|216548382 WD repeat domain 47 isoform 3 [Homo sapiens]
Length = 919
Score = 57.4 bits (137), Expect = 4e-08
Identities = 56/203 (27%), Positives = 91/203 (44%), Gaps = 26/203 (12%)
Query: 46 HSGCVNCLEWNEKGDLLASGSDDQHTIVWDPLHHKKL--------LSMHTGHTANIFSVK 97
H G + C+ W+ G LLA+GS+D++ V P + + SMH G ++ ++
Sbjct: 660 HKGSIYCVAWSPCGQLLATGSNDKYVKVL-PFNAETCNATGPDLEFSMHDGTIRDLAFME 718
Query: 98 FLPHAGDRILIT-GAADSKVHVHDLTVKETIHMFGDHTNRVKRIATAPMWPNTFWSAAED 156
P +G ILI+ GA D ++ D + +H HT + + T W S ++D
Sbjct: 719 G-PESGGAILISAGAGDCNIYTTDCQRGQGLHALSGHTGHILALYTWSGW--MIASGSQD 775
Query: 157 GLIRQYDLRENSKHSEVLIDLTEYCGQLVEAKCLTVNPQDNNCLAVGASGPFVRLYDI-- 214
+R +DLR S V + T + G + V+P LA G LYDI
Sbjct: 776 KTVRFWDLRVPSC---VRVVGTTFHGTGSAVASVAVDP-SGRLLATGQEDSSCMLYDIRG 831
Query: 215 -RMIHNHR------KSMKQSPSA 230
RM+ ++ +S++ SP A
Sbjct: 832 GRMVQSYHPHSSDVRSVRFSPGA 854
Score = 43.5 bits (101), Expect = 6e-04
Identities = 30/97 (30%), Positives = 52/97 (53%), Gaps = 7/97 (7%)
Query: 45 GHSGCVNCLEWNEKGDLLASGSDDQHTIVWDPLHHKKLLSMHTGHTANIFSVKFLPHAGD 104
G V + + G LLA+G +D +++D + + S H H++++ SV+F P G
Sbjct: 798 GTGSAVASVAVDPSGRLLATGQEDSSCMLYDIRGGRMVQSYHP-HSSDVRSVRFSP--GA 854
Query: 105 RILITGAADSKVHV----HDLTVKETIHMFGDHTNRV 137
L+TG+ D K+ V DLT + I + G+H ++V
Sbjct: 855 HYLLTGSYDMKIKVTDLQGDLTKQLPIMVVGEHKDKV 891
>gi|216548378 WD repeat domain 47 isoform 1 [Homo sapiens]
Length = 927
Score = 57.4 bits (137), Expect = 4e-08
Identities = 56/203 (27%), Positives = 91/203 (44%), Gaps = 26/203 (12%)
Query: 46 HSGCVNCLEWNEKGDLLASGSDDQHTIVWDPLHHKKL--------LSMHTGHTANIFSVK 97
H G + C+ W+ G LLA+GS+D++ V P + + SMH G ++ ++
Sbjct: 668 HKGSIYCVAWSPCGQLLATGSNDKYVKVL-PFNAETCNATGPDLEFSMHDGTIRDLAFME 726
Query: 98 FLPHAGDRILIT-GAADSKVHVHDLTVKETIHMFGDHTNRVKRIATAPMWPNTFWSAAED 156
P +G ILI+ GA D ++ D + +H HT + + T W S ++D
Sbjct: 727 G-PESGGAILISAGAGDCNIYTTDCQRGQGLHALSGHTGHILALYTWSGW--MIASGSQD 783
Query: 157 GLIRQYDLRENSKHSEVLIDLTEYCGQLVEAKCLTVNPQDNNCLAVGASGPFVRLYDI-- 214
+R +DLR S V + T + G + V+P LA G LYDI
Sbjct: 784 KTVRFWDLRVPSC---VRVVGTTFHGTGSAVASVAVDP-SGRLLATGQEDSSCMLYDIRG 839
Query: 215 -RMIHNHR------KSMKQSPSA 230
RM+ ++ +S++ SP A
Sbjct: 840 GRMVQSYHPHSSDVRSVRFSPGA 862
Score = 43.5 bits (101), Expect = 6e-04
Identities = 30/97 (30%), Positives = 52/97 (53%), Gaps = 7/97 (7%)
Query: 45 GHSGCVNCLEWNEKGDLLASGSDDQHTIVWDPLHHKKLLSMHTGHTANIFSVKFLPHAGD 104
G V + + G LLA+G +D +++D + + S H H++++ SV+F P G
Sbjct: 806 GTGSAVASVAVDPSGRLLATGQEDSSCMLYDIRGGRMVQSYHP-HSSDVRSVRFSP--GA 862
Query: 105 RILITGAADSKVHV----HDLTVKETIHMFGDHTNRV 137
L+TG+ D K+ V DLT + I + G+H ++V
Sbjct: 863 HYLLTGSYDMKIKVTDLQGDLTKQLPIMVVGEHKDKV 899
>gi|216548347 WD repeat domain 47 isoform 2 [Homo sapiens]
Length = 920
Score = 57.4 bits (137), Expect = 4e-08
Identities = 56/203 (27%), Positives = 91/203 (44%), Gaps = 26/203 (12%)
Query: 46 HSGCVNCLEWNEKGDLLASGSDDQHTIVWDPLHHKKL--------LSMHTGHTANIFSVK 97
H G + C+ W+ G LLA+GS+D++ V P + + SMH G ++ ++
Sbjct: 661 HKGSIYCVAWSPCGQLLATGSNDKYVKVL-PFNAETCNATGPDLEFSMHDGTIRDLAFME 719
Query: 98 FLPHAGDRILIT-GAADSKVHVHDLTVKETIHMFGDHTNRVKRIATAPMWPNTFWSAAED 156
P +G ILI+ GA D ++ D + +H HT + + T W S ++D
Sbjct: 720 G-PESGGAILISAGAGDCNIYTTDCQRGQGLHALSGHTGHILALYTWSGW--MIASGSQD 776
Query: 157 GLIRQYDLRENSKHSEVLIDLTEYCGQLVEAKCLTVNPQDNNCLAVGASGPFVRLYDI-- 214
+R +DLR S V + T + G + V+P LA G LYDI
Sbjct: 777 KTVRFWDLRVPSC---VRVVGTTFHGTGSAVASVAVDP-SGRLLATGQEDSSCMLYDIRG 832
Query: 215 -RMIHNHR------KSMKQSPSA 230
RM+ ++ +S++ SP A
Sbjct: 833 GRMVQSYHPHSSDVRSVRFSPGA 855
Score = 43.5 bits (101), Expect = 6e-04
Identities = 30/97 (30%), Positives = 52/97 (53%), Gaps = 7/97 (7%)
Query: 45 GHSGCVNCLEWNEKGDLLASGSDDQHTIVWDPLHHKKLLSMHTGHTANIFSVKFLPHAGD 104
G V + + G LLA+G +D +++D + + S H H++++ SV+F P G
Sbjct: 799 GTGSAVASVAVDPSGRLLATGQEDSSCMLYDIRGGRMVQSYHP-HSSDVRSVRFSP--GA 855
Query: 105 RILITGAADSKVHV----HDLTVKETIHMFGDHTNRV 137
L+TG+ D K+ V DLT + I + G+H ++V
Sbjct: 856 HYLLTGSYDMKIKVTDLQGDLTKQLPIMVVGEHKDKV 892
>gi|156627581 tetratricopeptide repeat domain 4 [Homo sapiens]
Length = 387
Score = 57.4 bits (137), Expect = 4e-08
Identities = 39/110 (35%), Positives = 59/110 (53%), Gaps = 11/110 (10%)
Query: 352 SPQVELPPYLERVKQQANEAFACQQWTQAIQLYSKAVQRA----PHNAMLYGNRAAAYMK 407
SP+ + Y K + N+ F + + +A+ Y++ +++ NA+LY NRAAA
Sbjct: 74 SPEEQAKTY----KDEGNDYFKEKDYKKAVISYTEGLKKKCADPDLNAVLYTNRAAA--- 126
Query: 408 RKWDGDHYDALRDCLKAISLNPCHLKAHFRLARCLFELKYVAEALECLDD 457
+ + G+ AL D A L PCHLKA R A C ELK+ AEA+ D+
Sbjct: 127 QYYLGNFRSALNDVTAARKLKPCHLKAIIRGALCHLELKHFAEAVNWCDE 176
>gi|54607135 translocase of outer mitochondrial membrane 70 homolog
A [Homo sapiens]
Length = 608
Score = 57.0 bits (136), Expect = 6e-08
Identities = 50/172 (29%), Positives = 80/172 (46%), Gaps = 18/172 (10%)
Query: 362 ERVKQQANEAFACQQWTQAIQLYSKAVQRAPHN-----AMLYGNRAAAYMK-RKWDGDHY 415
+ K + N+ F ++ QAIQ Y++A+ P + Y NRAAA+ + +KW
Sbjct: 115 QAAKNKGNKYFKAGKYEQAIQCYTEAISLCPTEKNVDLSTFYQNRAAAFEQLQKWK---- 170
Query: 416 DALRDCLKAISLNPCHLKAHFRLARCLFELKYVAEALECLDDFKGKFPEQAHSSACDALG 475
+ +DC KA+ LNP ++KA FR A+ +L ECL+D + + L
Sbjct: 171 EVAQDCTKAVELNPKYVKALFRRAKAHEKLD---NKKECLEDVTAVCILEGFQNQQSMLL 227
Query: 476 RDITAALFSKNDGEEK---KGPGGGAPVRLRS--TSRKDSISEDEMVLRERS 522
D L K +EK + P +P ++S +S D I M+ E+S
Sbjct: 228 ADKVLKLLGKEKAKEKYKNREPLMPSPQFIKSYFSSFTDDIISQPMLKGEKS 279
>gi|24308141 small glutamine-rich tetratricopeptide repeat
(TPR)-containing, beta [Homo sapiens]
Length = 304
Score = 55.8 bits (133), Expect = 1e-07
Identities = 30/91 (32%), Positives = 53/91 (58%), Gaps = 3/91 (3%)
Query: 362 ERVKQQANEAFACQQWTQAIQLYSKAVQRAPHNAMLYGNRAAAYMKRKWDGDHYDALRDC 421
+++K + N + + A+ Y++A++ P+NA+ Y NRAAA K G + DA++DC
Sbjct: 86 DQLKDEGNNHMKEENYAAAVDCYTQAIELDPNNAVYYCNRAAAQSKL---GHYTDAIKDC 142
Query: 422 LKAISLNPCHLKAHFRLARCLFELKYVAEAL 452
KAI+++ + KA+ R+ L L EA+
Sbjct: 143 EKAIAIDSKYSKAYGRMGLALTALNKFEEAV 173
>gi|224028289 tetratricopeptide repeat domain 28 [Homo sapiens]
Length = 2481
Score = 55.5 bits (132), Expect = 2e-07
Identities = 41/101 (40%), Positives = 58/101 (57%), Gaps = 6/101 (5%)
Query: 353 PQVELPPYLERVKQQANEAFACQQWTQAIQLYSKAVQRAPHNAMLYGNRAAAYMKRKWDG 412
P + ++E+V+Q +N+A + AI LY++A+ P N +LY NR+AAYMK +
Sbjct: 51 PVLSKAEFVEKVRQ-SNQACHDGDFHTAIVLYNEALAVDPQNCILYSNRSAAYMKIQ--- 106
Query: 413 DHYD-ALRDCLKAISLNPCHLKAHFRLARCLFELKYVAEAL 452
YD AL D +KA LNP KA+FR L L A+AL
Sbjct: 107 -QYDKALDDAIKARLLNPKWPKAYFRQGVALQYLGRHADAL 146
>gi|73747840 LON peptidase N-terminal domain and ring finger 3
isoform 1 [Homo sapiens]
Length = 759
Score = 55.1 bits (131), Expect = 2e-07
Identities = 44/165 (26%), Positives = 75/165 (45%), Gaps = 16/165 (9%)
Query: 358 PPYLERVKQQANEAFACQQWTQAIQLYSKAVQRAPHNAMLYGNRAAAYMKRKWDGDHYDA 417
P +++ + N + +Q A+ Y++AV+ AP++ +LY NR+ Y + H +A
Sbjct: 240 PARASQLRHEGNRLYRERQVEAALLKYNEAVKLAPNDHLLYSNRSQIYFTLE---SHENA 296
Query: 418 LRDCLKAISLNPCHLKAHFRLARCLFELKYVAEALE----CLD-DFKGKFPEQAHSSACD 472
L D A L P KAHFR A+ L L V EAL C+ D K K + C+
Sbjct: 297 LHDAEIACKLRPMGFKAHFRKAQALATLGKVEEALREFLYCVSLDGKNK------RARCE 350
Query: 473 ALGRDITAALFSKNDGEEKKGPGGGA--PVRLRSTSRKDSISEDE 515
A ++ S + +G G P +++ ++ + + E
Sbjct: 351 AQRDNLELPHCSSQEEAAARGDGSSLMDPAKVKGDGQQHHMKDQE 395
>gi|213021190 transducin beta-like 1X isoform b [Homo sapiens]
Length = 526
Score = 54.7 bits (130), Expect = 3e-07
Identities = 63/242 (26%), Positives = 99/242 (40%), Gaps = 26/242 (10%)
Query: 39 LEAELQGHSGCVNCLEWNEKGDLLASGSDDQHTIVWDPLHHKKLLSMHTGHTANIFSVKF 98
L + L H G + L+WN KG+ + S D+ TI+WD H + H+A V +
Sbjct: 270 LASTLGQHKGPIFALKWNRKGNYILSAGVDKTTIIWD-AHTGEAKQQFPFHSAPALDVDW 328
Query: 99 LPHAGDRILITGAADSKVHVHDLTVKETIHMFGDHTNRVKRIATAPMWPNTFWSAAEDGL 158
+ + + D +HV L + F HTN V I P S ++D
Sbjct: 329 ---QNNTTFASCSTDMCIHVCRLGCDRPVKTFQGHTNEVNAIKWDPS-GMLLASCSDDMT 384
Query: 159 IRQYDLRENSKHSEVLI-DLTEYCGQLVEAKC-----LTVNPQDNNCLAVGASGPFVRLY 212
++ + +++ EV I DL + ++ K T NP N LA + VRL+
Sbjct: 385 LKIWSMKQ-----EVCIHDLQAHNKEIYTIKWSPTGPATSNPNSNIMLASASFDSTVRLW 439
Query: 213 DI-RMIHNHRKSMKQSPSAGVHTFCDRQKPLPDGAAQYYVAGHLPVKLPDYNNRLRVLVA 271
DI R + H + Q P V PDG +Y +G + +N + LV
Sbjct: 440 DIERGVCTHTLTKHQEPVYSVAF-------SPDG--KYLASGSFDKCVHIWNTQSGNLVH 490
Query: 272 TY 273
+Y
Sbjct: 491 SY 492
Score = 33.1 bits (74), Expect = 0.86
Identities = 15/33 (45%), Positives = 18/33 (54%)
Query: 43 LQGHSGCVNCLEWNEKGDLLASGSDDQHTIVWD 75
L+GH V WN DLLASGS D +W+
Sbjct: 177 LRGHESEVFICAWNPVSDLLASGSGDSTARIWN 209
Score = 32.0 bits (71), Expect = 1.9
Identities = 29/94 (30%), Positives = 39/94 (41%), Gaps = 8/94 (8%)
Query: 491 KKGPGGGAPVRLRSTSRKDSISEDEMVLRERSYDYQFRYCGHCNTTTDIKEANF---FGS 547
K P G A S S S D V R +D + C H T T +E + F
Sbjct: 410 KWSPTGPATSNPNSNIMLASASFDSTV---RLWDIERGVCTH--TLTKHQEPVYSVAFSP 464
Query: 548 NAQYIVSGSDDGSFFIWEKETTNLVRVLQGDESI 581
+ +Y+ SGS D IW ++ NLV +G I
Sbjct: 465 DGKYLASGSFDKCVHIWNTQSGNLVHSYRGTGGI 498
>gi|213021188 transducin beta-like 1X isoform b [Homo sapiens]
Length = 526
Score = 54.7 bits (130), Expect = 3e-07
Identities = 63/242 (26%), Positives = 99/242 (40%), Gaps = 26/242 (10%)
Query: 39 LEAELQGHSGCVNCLEWNEKGDLLASGSDDQHTIVWDPLHHKKLLSMHTGHTANIFSVKF 98
L + L H G + L+WN KG+ + S D+ TI+WD H + H+A V +
Sbjct: 270 LASTLGQHKGPIFALKWNRKGNYILSAGVDKTTIIWD-AHTGEAKQQFPFHSAPALDVDW 328
Query: 99 LPHAGDRILITGAADSKVHVHDLTVKETIHMFGDHTNRVKRIATAPMWPNTFWSAAEDGL 158
+ + + D +HV L + F HTN V I P S ++D
Sbjct: 329 ---QNNTTFASCSTDMCIHVCRLGCDRPVKTFQGHTNEVNAIKWDPS-GMLLASCSDDMT 384
Query: 159 IRQYDLRENSKHSEVLI-DLTEYCGQLVEAKC-----LTVNPQDNNCLAVGASGPFVRLY 212
++ + +++ EV I DL + ++ K T NP N LA + VRL+
Sbjct: 385 LKIWSMKQ-----EVCIHDLQAHNKEIYTIKWSPTGPATSNPNSNIMLASASFDSTVRLW 439
Query: 213 DI-RMIHNHRKSMKQSPSAGVHTFCDRQKPLPDGAAQYYVAGHLPVKLPDYNNRLRVLVA 271
DI R + H + Q P V PDG +Y +G + +N + LV
Sbjct: 440 DIERGVCTHTLTKHQEPVYSVAF-------SPDG--KYLASGSFDKCVHIWNTQSGNLVH 490
Query: 272 TY 273
+Y
Sbjct: 491 SY 492
Score = 33.1 bits (74), Expect = 0.86
Identities = 15/33 (45%), Positives = 18/33 (54%)
Query: 43 LQGHSGCVNCLEWNEKGDLLASGSDDQHTIVWD 75
L+GH V WN DLLASGS D +W+
Sbjct: 177 LRGHESEVFICAWNPVSDLLASGSGDSTARIWN 209
Score = 32.0 bits (71), Expect = 1.9
Identities = 29/94 (30%), Positives = 39/94 (41%), Gaps = 8/94 (8%)
Query: 491 KKGPGGGAPVRLRSTSRKDSISEDEMVLRERSYDYQFRYCGHCNTTTDIKEANF---FGS 547
K P G A S S S D V R +D + C H T T +E + F
Sbjct: 410 KWSPTGPATSNPNSNIMLASASFDSTV---RLWDIERGVCTH--TLTKHQEPVYSVAFSP 464
Query: 548 NAQYIVSGSDDGSFFIWEKETTNLVRVLQGDESI 581
+ +Y+ SGS D IW ++ NLV +G I
Sbjct: 465 DGKYLASGSFDKCVHIWNTQSGNLVHSYRGTGGI 498
>gi|213021186 transducin beta-like 1X isoform a [Homo sapiens]
Length = 577
Score = 54.7 bits (130), Expect = 3e-07
Identities = 63/242 (26%), Positives = 99/242 (40%), Gaps = 26/242 (10%)
Query: 39 LEAELQGHSGCVNCLEWNEKGDLLASGSDDQHTIVWDPLHHKKLLSMHTGHTANIFSVKF 98
L + L H G + L+WN KG+ + S D+ TI+WD H + H+A V +
Sbjct: 321 LASTLGQHKGPIFALKWNRKGNYILSAGVDKTTIIWD-AHTGEAKQQFPFHSAPALDVDW 379
Query: 99 LPHAGDRILITGAADSKVHVHDLTVKETIHMFGDHTNRVKRIATAPMWPNTFWSAAEDGL 158
+ + + D +HV L + F HTN V I P S ++D
Sbjct: 380 ---QNNTTFASCSTDMCIHVCRLGCDRPVKTFQGHTNEVNAIKWDPS-GMLLASCSDDMT 435
Query: 159 IRQYDLRENSKHSEVLI-DLTEYCGQLVEAKC-----LTVNPQDNNCLAVGASGPFVRLY 212
++ + +++ EV I DL + ++ K T NP N LA + VRL+
Sbjct: 436 LKIWSMKQ-----EVCIHDLQAHNKEIYTIKWSPTGPATSNPNSNIMLASASFDSTVRLW 490
Query: 213 DI-RMIHNHRKSMKQSPSAGVHTFCDRQKPLPDGAAQYYVAGHLPVKLPDYNNRLRVLVA 271
DI R + H + Q P V PDG +Y +G + +N + LV
Sbjct: 491 DIERGVCTHTLTKHQEPVYSVAF-------SPDG--KYLASGSFDKCVHIWNTQSGNLVH 541
Query: 272 TY 273
+Y
Sbjct: 542 SY 543
Score = 33.1 bits (74), Expect = 0.86
Identities = 15/33 (45%), Positives = 18/33 (54%)
Query: 43 LQGHSGCVNCLEWNEKGDLLASGSDDQHTIVWD 75
L+GH V WN DLLASGS D +W+
Sbjct: 228 LRGHESEVFICAWNPVSDLLASGSGDSTARIWN 260
Score = 32.0 bits (71), Expect = 1.9
Identities = 29/94 (30%), Positives = 39/94 (41%), Gaps = 8/94 (8%)
Query: 491 KKGPGGGAPVRLRSTSRKDSISEDEMVLRERSYDYQFRYCGHCNTTTDIKEANF---FGS 547
K P G A S S S D V R +D + C H T T +E + F
Sbjct: 461 KWSPTGPATSNPNSNIMLASASFDSTV---RLWDIERGVCTH--TLTKHQEPVYSVAFSP 515
Query: 548 NAQYIVSGSDDGSFFIWEKETTNLVRVLQGDESI 581
+ +Y+ SGS D IW ++ NLV +G I
Sbjct: 516 DGKYLASGSFDKCVHIWNTQSGNLVHSYRGTGGI 549
>gi|5032159 transducin beta-like 1X isoform a [Homo sapiens]
Length = 577
Score = 54.7 bits (130), Expect = 3e-07
Identities = 63/242 (26%), Positives = 99/242 (40%), Gaps = 26/242 (10%)
Query: 39 LEAELQGHSGCVNCLEWNEKGDLLASGSDDQHTIVWDPLHHKKLLSMHTGHTANIFSVKF 98
L + L H G + L+WN KG+ + S D+ TI+WD H + H+A V +
Sbjct: 321 LASTLGQHKGPIFALKWNRKGNYILSAGVDKTTIIWD-AHTGEAKQQFPFHSAPALDVDW 379
Query: 99 LPHAGDRILITGAADSKVHVHDLTVKETIHMFGDHTNRVKRIATAPMWPNTFWSAAEDGL 158
+ + + D +HV L + F HTN V I P S ++D
Sbjct: 380 ---QNNTTFASCSTDMCIHVCRLGCDRPVKTFQGHTNEVNAIKWDPS-GMLLASCSDDMT 435
Query: 159 IRQYDLRENSKHSEVLI-DLTEYCGQLVEAKC-----LTVNPQDNNCLAVGASGPFVRLY 212
++ + +++ EV I DL + ++ K T NP N LA + VRL+
Sbjct: 436 LKIWSMKQ-----EVCIHDLQAHNKEIYTIKWSPTGPATSNPNSNIMLASASFDSTVRLW 490
Query: 213 DI-RMIHNHRKSMKQSPSAGVHTFCDRQKPLPDGAAQYYVAGHLPVKLPDYNNRLRVLVA 271
DI R + H + Q P V PDG +Y +G + +N + LV
Sbjct: 491 DIERGVCTHTLTKHQEPVYSVAF-------SPDG--KYLASGSFDKCVHIWNTQSGNLVH 541
Query: 272 TY 273
+Y
Sbjct: 542 SY 543
Score = 33.1 bits (74), Expect = 0.86
Identities = 15/33 (45%), Positives = 18/33 (54%)
Query: 43 LQGHSGCVNCLEWNEKGDLLASGSDDQHTIVWD 75
L+GH V WN DLLASGS D +W+
Sbjct: 228 LRGHESEVFICAWNPVSDLLASGSGDSTARIWN 260
Score = 32.0 bits (71), Expect = 1.9
Identities = 29/94 (30%), Positives = 39/94 (41%), Gaps = 8/94 (8%)
Query: 491 KKGPGGGAPVRLRSTSRKDSISEDEMVLRERSYDYQFRYCGHCNTTTDIKEANF---FGS 547
K P G A S S S D V R +D + C H T T +E + F
Sbjct: 461 KWSPTGPATSNPNSNIMLASASFDSTV---RLWDIERGVCTH--TLTKHQEPVYSVAFSP 515
Query: 548 NAQYIVSGSDDGSFFIWEKETTNLVRVLQGDESI 581
+ +Y+ SGS D IW ++ NLV +G I
Sbjct: 516 DGKYLASGSFDKCVHIWNTQSGNLVHSYRGTGGI 549
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.135 0.414
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,212,719
Number of Sequences: 37866
Number of extensions: 1270156
Number of successful extensions: 4526
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 184
Number of HSP's successfully gapped in prelim test: 125
Number of HSP's that attempted gapping in prelim test: 3011
Number of HSP's gapped (non-prelim): 1444
length of query: 676
length of database: 18,247,518
effective HSP length: 109
effective length of query: 567
effective length of database: 14,120,124
effective search space: 8006110308
effective search space used: 8006110308
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.