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Search of human proteins with 218931148
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|218931148 neuronal tropomodulin isoform b [Homo sapiens]
(315 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|218931148 neuronal tropomodulin isoform b [Homo sapiens] 616 e-177
gi|7657647 neuronal tropomodulin isoform a [Homo sapiens] 598 e-171
gi|7657649 tropomodulin 3 (ubiquitous) [Homo sapiens] 454 e-128
gi|4507553 tropomodulin 1 [Homo sapiens] 345 3e-95
gi|156415984 tropomodulin 4 (muscle) [Homo sapiens] 321 6e-88
gi|150378503 leiomodin 2 (cardiac) [Homo sapiens] 197 1e-50
gi|54607116 leiomodin 3 (fetal) [Homo sapiens] 152 3e-37
gi|112380630 leiomodin 1 (smooth muscle) [Homo sapiens] 120 2e-27
gi|118918429 NOD3 protein [Homo sapiens] 51 1e-06
gi|5174617 nucleotide-binding oligomerization domain containing ... 47 3e-05
gi|168986655 hypothetical protein LOC145497 [Homo sapiens] 43 3e-04
gi|11545912 nucleotide-binding oligomerization domain containing... 38 0.013
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s... 38 0.013
gi|253970456 HIV-1 Tat specific factor 1 [Homo sapiens] 37 0.023
gi|21361437 HIV-1 Tat specific factor 1 [Homo sapiens] 37 0.023
gi|119703749 hydrocephalus inducing isoform a [Homo sapiens] 36 0.051
gi|149274621 centrosomal protein 78kDa isoform a [Homo sapiens] 35 0.066
gi|149274651 centrosomal protein 78kDa isoform b [Homo sapiens] 35 0.066
gi|224586773 hypothetical protein LOC643854 [Homo sapiens] 35 0.11
gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens] 35 0.11
gi|194018482 NLR family, pyrin domain containing 4 [Homo sapiens] 34 0.15
gi|48255881 troponin T type 2, cardiac isoform 3 [Homo sapiens] 34 0.19
gi|48255879 troponin T type 2, cardiac isoform 2 [Homo sapiens] 34 0.19
gi|33667040 NLR family, pyrin domain containing 8 [Homo sapiens] 34 0.19
gi|229577123 t-complex-associated testis expressed 1 [Homo sapiens] 33 0.25
gi|133908641 myosin binding protein C, fast type [Homo sapiens] 33 0.25
gi|193290160 CTAGE family, member 4 [Homo sapiens] 33 0.33
gi|22538457 nuclear receptor coactivator 1 isoform 2 [Homo sapiens] 33 0.33
gi|22538459 nuclear receptor coactivator 1 isoform 3 [Homo sapiens] 33 0.33
gi|22538455 nuclear receptor coactivator 1 isoform 1 [Homo sapiens] 33 0.33
>gi|218931148 neuronal tropomodulin isoform b [Homo sapiens]
Length = 315
Score = 616 bits (1589), Expect = e-177
Identities = 315/315 (100%), Positives = 315/315 (100%)
Query: 1 MALPFQKELEKYKNIDEDELLGKLSEEELKQLENVLDDLDPESAMLPAGFRQKDQTQKAA 60
MALPFQKELEKYKNIDEDELLGKLSEEELKQLENVLDDLDPESAMLPAGFRQKDQTQKAA
Sbjct: 1 MALPFQKELEKYKNIDEDELLGKLSEEELKQLENVLDDLDPESAMLPAGFRQKDQTQKAA 60
Query: 61 TGPFDREHLLMYLEKEALEQKDREDFVPFTGEKKGRVFIPKEKPIETRKEEKVTLDPELE 120
TGPFDREHLLMYLEKEALEQKDREDFVPFTGEKKGRVFIPKEKPIETRKEEKVTLDPELE
Sbjct: 61 TGPFDREHLLMYLEKEALEQKDREDFVPFTGEKKGRVFIPKEKPIETRKEEKVTLDPELE 120
Query: 121 EALASASDTELYDLAAVLGVHNLLNNPKFDEETANNKGGKGPVRNVVKGEKVKPVFEEPP 180
EALASASDTELYDLAAVLGVHNLLNNPKFDEETANNKGGKGPVRNVVKGEKVKPVFEEPP
Sbjct: 121 EALASASDTELYDLAAVLGVHNLLNNPKFDEETANNKGGKGPVRNVVKGEKVKPVFEEPP 180
Query: 181 NPTNVEISLQQMKANDPSLQEVNLNNIKAFADMLKVNKTLTSLNIESNFITGTGILALVE 240
NPTNVEISLQQMKANDPSLQEVNLNNIKAFADMLKVNKTLTSLNIESNFITGTGILALVE
Sbjct: 181 NPTNVEISLQQMKANDPSLQEVNLNNIKAFADMLKVNKTLTSLNIESNFITGTGILALVE 240
Query: 241 ALKENDTLTEIKIDNQRQQLGTAVEMEIAQMLEENSRILKFGYQFTKQGPRTRVAAAITK 300
ALKENDTLTEIKIDNQRQQLGTAVEMEIAQMLEENSRILKFGYQFTKQGPRTRVAAAITK
Sbjct: 241 ALKENDTLTEIKIDNQRQQLGTAVEMEIAQMLEENSRILKFGYQFTKQGPRTRVAAAITK 300
Query: 301 NNDLVRKKRVEADRR 315
NNDLVRKKRVEADRR
Sbjct: 301 NNDLVRKKRVEADRR 315
>gi|7657647 neuronal tropomodulin isoform a [Homo sapiens]
Length = 351
Score = 598 bits (1542), Expect = e-171
Identities = 315/351 (89%), Positives = 315/351 (89%), Gaps = 36/351 (10%)
Query: 1 MALPFQKELEKYKNIDEDELLGKLSEEELKQLENVLDDLDPESAMLPAGFRQKDQTQKAA 60
MALPFQKELEKYKNIDEDELLGKLSEEELKQLENVLDDLDPESAMLPAGFRQKDQTQKAA
Sbjct: 1 MALPFQKELEKYKNIDEDELLGKLSEEELKQLENVLDDLDPESAMLPAGFRQKDQTQKAA 60
Query: 61 TGPFDREHLLMYLEKEALEQKDREDFVPFTGEKKGRVFIPKEKPIETRKEEKVTLDPELE 120
TGPFDREHLLMYLEKEALEQKDREDFVPFTGEKKGRVFIPKEKPIETRKEEKVTLDPELE
Sbjct: 61 TGPFDREHLLMYLEKEALEQKDREDFVPFTGEKKGRVFIPKEKPIETRKEEKVTLDPELE 120
Query: 121 EALASASDTELYDLAAVLGVHNLLNNPKFDEETANNKGGKGPVRNVVKGEKVKPVFEEPP 180
EALASASDTELYDLAAVLGVHNLLNNPKFDEETANNKGGKGPVRNVVKGEKVKPVFEEPP
Sbjct: 121 EALASASDTELYDLAAVLGVHNLLNNPKFDEETANNKGGKGPVRNVVKGEKVKPVFEEPP 180
Query: 181 NPTNVEISLQQMKANDPSLQEVNLNNIK-------------------------------- 208
NPTNVEISLQQMKANDPSLQEVNLNNIK
Sbjct: 181 NPTNVEISLQQMKANDPSLQEVNLNNIKNIPIPTLREFAKALETNTHVKKFSLAATRSND 240
Query: 209 ----AFADMLKVNKTLTSLNIESNFITGTGILALVEALKENDTLTEIKIDNQRQQLGTAV 264
AFADMLKVNKTLTSLNIESNFITGTGILALVEALKENDTLTEIKIDNQRQQLGTAV
Sbjct: 241 PVAIAFADMLKVNKTLTSLNIESNFITGTGILALVEALKENDTLTEIKIDNQRQQLGTAV 300
Query: 265 EMEIAQMLEENSRILKFGYQFTKQGPRTRVAAAITKNNDLVRKKRVEADRR 315
EMEIAQMLEENSRILKFGYQFTKQGPRTRVAAAITKNNDLVRKKRVEADRR
Sbjct: 301 EMEIAQMLEENSRILKFGYQFTKQGPRTRVAAAITKNNDLVRKKRVEADRR 351
>gi|7657649 tropomodulin 3 (ubiquitous) [Homo sapiens]
Length = 352
Score = 454 bits (1169), Expect = e-128
Identities = 235/352 (66%), Positives = 276/352 (78%), Gaps = 37/352 (10%)
Query: 1 MALPFQKELEKYKNIDEDELLGKLSEEELKQLENVLDDLDPESAMLPAGFRQKDQTQKAA 60
MALPF+K+LEKYK++DEDELLG LSE ELKQLE VLDDLDPE+A+LPAGFRQK+QT K+
Sbjct: 1 MALPFRKDLEKYKDLDEDELLGNLSETELKQLETVLDDLDPENALLPAGFRQKNQTSKST 60
Query: 61 TGPFDREHLLMYLEKEALEQKDREDFVPFTGEKKGRVFIPKEKPIETRKEEKVTLDPELE 120
TGPFDREHLL YLEKEALE KDRED+VP+TGEKKG++FIPK+KP++T EEKV+LDPELE
Sbjct: 61 TGPFDREHLLSYLEKEALEHKDREDYVPYTGEKKGKIFIPKQKPVQTFTEEKVSLDPELE 120
Query: 121 EALASASDTELYDLAAVLGVHNLLNNPKFDEETANNKG-GKGPVRNVVKGEKVKPVFEEP 179
EAL SASDTEL DLAA+LG+HNL+ N KF ++ G + NVVKGEK+ PVF+EP
Sbjct: 121 EALTSASDTELCDLAAILGMHNLITNTKFCNIMGSSNGVDQEHFSNVVKGEKILPVFDEP 180
Query: 180 PNPTNVEISLQQMKANDPSLQEVNLNNIK------------------------------- 208
PNPTNVE SL++ K ND L EVNLNNIK
Sbjct: 181 PNPTNVEESLKRTKENDAHLVEVNLNNIKNIPIPTLKDFAKALETNTHVKCFSLAATRSN 240
Query: 209 -----AFADMLKVNKTLTSLNIESNFITGTGILALVEALKENDTLTEIKIDNQRQQLGTA 263
AFA+MLKVNKTL SLN+ESNFITG GILAL++AL++N+TL E+KIDNQRQQLGTA
Sbjct: 241 DPVATAFAEMLKVNKTLKSLNVESNFITGVGILALIDALRDNETLAELKIDNQRQQLGTA 300
Query: 264 VEMEIAQMLEENSRILKFGYQFTKQGPRTRVAAAITKNNDLVRKKRVEADRR 315
VE+E+A+MLEEN+ ILKFGYQFT+QGPRTR A AITKNNDLVRK+RVE D +
Sbjct: 301 VELEMAKMLEENTNILKFGYQFTQQGPRTRAANAITKNNDLVRKRRVEGDHQ 352
>gi|4507553 tropomodulin 1 [Homo sapiens]
Length = 359
Score = 345 bits (885), Expect = 3e-95
Identities = 182/345 (52%), Positives = 245/345 (71%), Gaps = 38/345 (11%)
Query: 3 LPFQKELEKYKNIDEDELLGKLSEEELKQLENVLDDLDPESAMLPAGFRQKDQTQKAATG 62
+ +++ELEKY+++DEDE+LG L+EEEL+ LEN LD+LDP++A+LPAG RQKDQT KA TG
Sbjct: 1 MSYRRELEKYRDLDEDEILGALTEEELRTLENELDELDPDNALLPAGLRQKDQTTKAPTG 60
Query: 63 PFDREHLLMYLEKEALEQKDREDFVPFTGEKKGRVFIPKEKPIETRKEEKVTLDPELEEA 122
PF RE LL +LEK+A E KDRED VP+TGEK+G+V++PK+KP++ E VTL+PELEEA
Sbjct: 61 PFKREELLDHLEKQAKEFKDREDLVPYTGEKRGKVWVPKQKPLDP-VLESVTLEPELEEA 119
Query: 123 LASASDTELYDLAAVLGVHNLLNNPKFDEETANNK-GGKGPVRNVVKGEKVKPVFEEPPN 181
LA+ASD EL D+AA+LG+H L++N ++ + +++ K + +V+K + KPV +E PN
Sbjct: 120 LANASDAELCDIAAILGMHTLMSNQQYYQALSSSSIMNKEGLNSVIKPTQYKPVPDEEPN 179
Query: 182 PTNVEISLQQMKANDPSLQEVNLNNIK--------------------------------- 208
T+VE +L+++K NDP L+EVNLNNI+
Sbjct: 180 STDVEETLERIKNNDPKLEEVNLNNIRNIPIPTLKAYAEALKENSYVKKFSIVGTRSNDP 239
Query: 209 ---AFADMLKVNKTLTSLNIESNFITGTGILALVEALKENDTLTEIKIDNQRQQLGTAVE 265
A A+MLK NK L +LN+ESNFI+G GIL LVEAL N +L E+KIDNQ Q LG VE
Sbjct: 240 VAYALAEMLKENKVLKTLNVESNFISGAGILRLVEALPYNTSLVEMKIDNQSQPLGNKVE 299
Query: 266 MEIAQMLEENSRILKFGYQFTKQGPRTRVAAAITKNNDLVRKKRV 310
MEI MLE+N+ +LKFGY FT+QGPR R + A+ NNDLVRK+R+
Sbjct: 300 MEIVSMLEKNATLLKFGYHFTQQGPRLRASNAMMNNNDLVRKRRL 344
>gi|156415984 tropomodulin 4 (muscle) [Homo sapiens]
Length = 345
Score = 321 bits (822), Expect = 6e-88
Identities = 169/346 (48%), Positives = 244/346 (70%), Gaps = 47/346 (13%)
Query: 5 FQKELEKYKNIDEDELLGKLSEEELKQLENVLDDLDPESAMLPAGFRQKDQTQKAATGPF 64
+QKELEKY++IDEDE+L LS EEL+QL+ L ++DPE+ +LPAG RQ+DQT+K+ TGP
Sbjct: 4 YQKELEKYRDIDEDEILRTLSPEELEQLDCELQEMDPENMLLPAGLRQRDQTKKSPTGPL 63
Query: 65 DREHLLMYLEKEALEQKDREDFVPFTGEKKGRVFIPKEKPIETRKEEKVTLDPELEEALA 124
DRE LL YLE++ALE K+R+D VPFTGEKKG+ +I ++ I EE++TL+PELEEALA
Sbjct: 64 DREALLQYLEQQALEVKERDDLVPFTGEKKGKPYIQPKREIPA--EEQITLEPELEEALA 121
Query: 125 SASDTELYDLAAVLGVHNLLNNPKFDE-----ETANNKGGKGPVRNVVKGEKVKPVFEEP 179
A+D E+ D+AA+L ++ L++N ++ + E N +G + +VV+ +K KPV +EP
Sbjct: 122 HATDAEMCDIAAILDMYTLMSNKQYYDALCSGEICNTEG----ISSVVQPDKYKPVPDEP 177
Query: 180 PNPTNVEISLQQMKANDPSLQEVNLNNIK------------------------------- 208
PNPTN+E L+++++ND L+EVNLNNI+
Sbjct: 178 PNPTNIEEILKRVRSNDKELEEVNLNNIQDIPIPMLSELCEAMKANTYVRSFSLVATRSG 237
Query: 209 -----AFADMLKVNKTLTSLNIESNFITGTGILALVEALKENDTLTEIKIDNQRQQLGTA 263
A ADML+ N++L SLNIESNFI+ TG++A+++A++EN TLTE+++DNQRQ G A
Sbjct: 238 DPIANAVADMLRENRSLQSLNIESNFISSTGLMAVLKAVRENATLTELRVDNQRQWPGDA 297
Query: 264 VEMEIAQMLEENSRILKFGYQFTKQGPRTRVAAAITKNNDLVRKKR 309
VEME+A +LE+ I++FGY FT+QGPR R A A+T+NN+L R+++
Sbjct: 298 VEMEMATVLEQCPSIVRFGYHFTQQGPRARAAQAMTRNNELRRQQK 343
>gi|150378503 leiomodin 2 (cardiac) [Homo sapiens]
Length = 547
Score = 197 bits (500), Expect = 1e-50
Identities = 128/370 (34%), Positives = 195/370 (52%), Gaps = 69/370 (18%)
Query: 5 FQKELEKYKNIDEDELLGKLSEEELKQLENVLDDLDPESAMLPAGFRQKDQTQKAATGPF 64
+++ L KY++IDEDELL LS EELK+LE L+D++P+ LP G RQK T+K TG F
Sbjct: 6 YRRGLSKYESIDEDELLASLSAEELKELERELEDIEPD-RNLPVGLRQKSLTEKTPTGTF 64
Query: 65 DREHLLMYLEKE----------------ALEQKDREDFVPFTGEKKGRVFIPKEKPIETR 108
RE L+ Y EKE A ++++ E+ + FT E V + + T
Sbjct: 65 SREALMAYWEKESQKLLEKERLGECGKVAEDKEESEEELIFT-ESNSEV----SEEVYTE 119
Query: 109 KEEKVTLDPELEEALASASDTELYDLAAVLGVHNLLNNPKFDEETANNKGGKGPVRNVVK 168
+EE+ + + E EE SD E + G++ +N + + + K K + N+
Sbjct: 120 EEEEESQEEEEEE----DSDEEERTIETAKGINGTVNYDSVNSDNSKPKIFKSQIENINL 175
Query: 169 GEKVKPVFEEPP-------NPTNVEISLQQMKANDPSLQEVNLNNIK------------- 208
E P NPT +E +L ++K+NDP EVNLNNI+
Sbjct: 176 TNGSNGRNTESPAAIHPCGNPTVIEDALDKIKSNDPDTTEVNLNNIENITTQTLTRFAEA 235
Query: 209 -----------------------AFADMLKVNKTLTSLNIESNFITGTGILALVEALKEN 245
A A+MLKVN+ +T++N+ESNFITG GILA++ AL+ N
Sbjct: 236 LKDNTVVKTFSLANTHADDSAAMAIAEMLKVNEHITNVNVESNFITGKGILAIMRALQHN 295
Query: 246 DTLTEIKIDNQRQQLGTAVEMEIAQMLEENSRILKFGYQFTKQGPRTRVAAAITKNNDLV 305
LTE++ NQR +G+ VEMEI ++L+EN+ +L+ GY F GPR + + +T+N D
Sbjct: 296 TVLTELRFHNQRHIMGSQVEMEIVKLLKENTTLLRLGYHFELPGPRMSMTSILTRNMDKQ 355
Query: 306 RKKRVEADRR 315
R+KR++ ++
Sbjct: 356 RQKRLQEQKQ 365
>gi|54607116 leiomodin 3 (fetal) [Homo sapiens]
Length = 560
Score = 152 bits (385), Expect = 3e-37
Identities = 120/393 (30%), Positives = 184/393 (46%), Gaps = 91/393 (23%)
Query: 13 KNIDEDELLGKLSEEELKQLENVLDDLDPESAMLPAGFRQKDQTQKAATGPFDREHLLMY 72
+ I+EDE+L LS EELK+L++ ++ + P+ + LP G QKDQT K TG F+ + L+ Y
Sbjct: 16 EEINEDEILANLSAEELKELQSEMEVMAPDPS-LPVGMIQKDQTDKPPTGNFNHKSLVDY 74
Query: 73 ----------LEKEAL-------EQKDREDFVPFTGEKKGRVFIPKEKP----IETRKEE 111
LE+E + E+K +E+ K KEK + ++E
Sbjct: 75 MYWEKASRRMLEEERVPVTFVKSEEKTQEEHEEIEKRNKNMAQYLKEKLNNEIVANKRES 134
Query: 112 KVT-----LDPELEEALASASDTELYDLA-------------AVLGVHNLLNN------- 146
K + D E EE D E D A + N NN
Sbjct: 135 KGSSNIQETDEEDEEEEDDDDDDEGEDDGEESEETNREEEGKAKEQIRNCENNCQQVTDK 194
Query: 147 --------PKFDEETANNKGGKGPVRNVVKGEKVKPVFEEPPNPTNVEISLQQMKANDPS 198
P+ E++ P + + +K N T+++ SL++++ NDP
Sbjct: 195 AFKEQRDRPEAQEQSEKKISKLDPKKLALDTSFLKVSTRPSGNQTDLDGSLRRVRKNDPD 254
Query: 199 LQEVNLNNIK------------------------------------AFADMLKVNKTLTS 222
++E+NLNNI+ A A+ML+ N+++T+
Sbjct: 255 MKELNLNNIENIPKEMLLDFVNAMKKNKHIKTFSLANVGADENVAFALANMLRENRSITT 314
Query: 223 LNIESNFITGTGILALVEALKENDTLTEIKIDNQRQQLGTAVEMEIAQMLEENSRILKFG 282
LNIESNFITG GI+A++ L+ N+TLTE++ NQR LG EMEIA++L+ N+ +LK G
Sbjct: 315 LNIESNFITGKGIVAIMRCLQFNETLTELRFHNQRHMLGHHAEMEIARLLKANNTLLKMG 374
Query: 283 YQFTKQGPRTRVAAAITKNNDLVRKKRVEADRR 315
Y F GPR V +T+N D R+KR E ++
Sbjct: 375 YHFELPGPRMVVTNLLTRNQDKQRQKRQEEQKQ 407
>gi|112380630 leiomodin 1 (smooth muscle) [Homo sapiens]
Length = 600
Score = 120 bits (301), Expect = 2e-27
Identities = 77/212 (36%), Positives = 110/212 (51%), Gaps = 42/212 (19%)
Query: 145 NNPKFDEETANNKGGKGPVRNVVKGEKVKPV-----FEEPPNPTNVEISLQQMKANDPSL 199
N P ++E ++ K P + G KP EE P+ + L+++K NDP +
Sbjct: 274 NEPLHEKEAKDDSKTKTPEKQTPSGP-TKPSEGPAKVEEEAAPSIFDEPLERVKNNDPEM 332
Query: 200 QEVNLNN---------------------IKAFA---------------DMLKVNKTLTSL 223
EVN+NN +K FA MLK NKT+TSL
Sbjct: 333 TEVNVNNSDCITNEILVRFTEALEFNTVVKLFALANTRADDHVAFAIAIMLKANKTITSL 392
Query: 224 NIESNFITGTGILALVEALKENDTLTEIKIDNQRQQLGTAVEMEIAQMLEENSRILKFGY 283
N++SN ITG GILA+ AL +N+TLTE++ NQR G EMEIA++L+EN+ +LK GY
Sbjct: 393 NLDSNHITGKGILAIFRALLQNNTLTELRFHNQRHICGGKTEMEIAKLLKENTTLLKLGY 452
Query: 284 QFTKQGPRTRVAAAITKNNDLVRKKRVEADRR 315
F GPR V +++N D R+KR++ R+
Sbjct: 453 HFELAGPRMTVTNLLSRNMDKQRQKRLQEQRQ 484
Score = 62.8 bits (151), Expect = 4e-10
Identities = 46/159 (28%), Positives = 77/159 (48%), Gaps = 18/159 (11%)
Query: 16 DEDELLGKLSEEELKQLENVLDDLDPESAMLPAGFRQKDQTQKAATGPFDREHLLMYLEK 75
D D LL LS EE+++LE LD +DP+ ++ P G RQ++QT+K +TG ++RE +L + EK
Sbjct: 16 DIDSLLETLSPEEMEELEKELDVVDPDGSV-PVGLRQRNQTEKQSTGVYNREAMLNFCEK 74
Query: 76 EALEQKDREDFVPFTGEKKGRVFIPKEKPIETRKEEKVTLDPELEEALASASDTELYDLA 135
E + RE + + + K +ET+ + K + + + + DL
Sbjct: 75 ETKKLMQRE------------MSMDESKQVETKTDAKNGEERGRDASKKALGPRRDSDLG 122
Query: 136 AVLGVHNLLNNPKFDEETANNKGGKGP-----VRNVVKG 169
L + D + A K G+ P +R + KG
Sbjct: 123 KEPKRGGLKKSFSRDRDEAGGKSGEKPKEEKIIRGIDKG 161
>gi|118918429 NOD3 protein [Homo sapiens]
Length = 1065
Score = 51.2 bits (121), Expect = 1e-06
Identities = 32/99 (32%), Positives = 51/99 (51%), Gaps = 4/99 (4%)
Query: 208 KAFADMLKVNKTLTSLNIESNFITGTGILALVEALKENDTLTEIKIDNQRQQLGTAVEME 267
KA AD LK+N+TLTSL+++ N + G ++ EAL N TL+ + + Q+ +G
Sbjct: 712 KALADALKINRTLTSLSLQGNTVRDDGARSMAEALASNRTLSMLHL--QKNSIGPMGAQR 769
Query: 268 IAQMLEENSRI--LKFGYQFTKQGPRTRVAAAITKNNDL 304
+A L++N + L F G +A A+ N L
Sbjct: 770 MADALKQNRSLKELMFSSNSIGDGGAKALAEALKVNQGL 808
Score = 47.0 bits (110), Expect = 2e-05
Identities = 39/111 (35%), Positives = 54/111 (48%), Gaps = 6/111 (5%)
Query: 198 SLQEVNLNN--IKAFADMLKVNKTLTSLNIESNFITGTGILALVEALKENDTLTEIKIDN 255
SL E ++N KA A L VN++LTSL++ N I G AL +ALK N TLT + +
Sbjct: 672 SLAENQISNKGAKALARSLLVNRSLTSLDLRGNSIGPQGAKALADALKINRTLTSLSLQG 731
Query: 256 QRQQLGTAVEMEIAQMLEENSRILKFGYQFTKQGP--RTRVAAAITKNNDL 304
+ A M A+ L N + Q GP R+A A+ +N L
Sbjct: 732 NTVRDDGARSM--AEALASNRTLSMLHLQKNSIGPMGAQRMADALKQNRSL 780
Score = 43.5 bits (101), Expect = 2e-04
Identities = 33/100 (33%), Positives = 49/100 (49%), Gaps = 6/100 (6%)
Query: 208 KAFADMLKVNKTLTSLNIESNFITGTGILALVEALKENDTLTEIKIDNQRQQLGTAVEME 267
KA A+ LKVN+ L SL+++SN I+ G+ AL+ AL N TL + + + +
Sbjct: 796 KALAEALKVNQGLESLDLQSNSISDAGVAALMGALCTNQTLLSLSL--RENSISPEGAQA 853
Query: 268 IAQMLEENSRILKFGYQ---FTKQGPRTRVAAAITKNNDL 304
IA L NS + QG R +A A+ +N L
Sbjct: 854 IAHALCANSTLKNLDLTANLLHDQGARA-IAVAVRENRTL 892
Score = 37.0 bits (84), Expect = 0.023
Identities = 25/83 (30%), Positives = 37/83 (44%), Gaps = 2/83 (2%)
Query: 202 VNLNNIKAFADMLKVNKTLTSLNIESNFITGTGILALVEALKENDTLTEIKIDNQRQQLG 261
+ + + + L VN+TL L++ N I G AL ALK N +L + + Q LG
Sbjct: 958 IGASGAQVLGEALAVNRTLEILDLRGNAIGVAGAKALANALKVNSSLRRLNL--QENSLG 1015
Query: 262 TAVEMEIAQMLEENSRILKFGYQ 284
+ IA L N R+ Q
Sbjct: 1016 MDGAICIATALSGNHRLQHINLQ 1038
Score = 36.6 bits (83), Expect = 0.030
Identities = 27/104 (25%), Positives = 47/104 (45%), Gaps = 10/104 (9%)
Query: 181 NPTNVEISLQQMKANDPSLQEVNLNNIKAFADMLKVNKTLTSLNIESNFITGTGILALVE 240
N T + +SL++ ++ +A A L N TL +L++ +N + G A+
Sbjct: 833 NQTLLSLSLRE--------NSISPEGAQAIAHALCANSTLKNLDLTANLLHDQGARAIAV 884
Query: 241 ALKENDTLTEIKIDNQRQQLGTAVEMEIAQMLEENSRILKFGYQ 284
A++EN TLT + + Q G A + Q L+ N + Q
Sbjct: 885 AVRENRTLTSLHLQWNFIQAGAA--QALGQALQLNRSLTSLDLQ 926
Score = 36.6 bits (83), Expect = 0.030
Identities = 21/75 (28%), Positives = 38/75 (50%), Gaps = 2/75 (2%)
Query: 202 VNLNNIKAFADMLKVNKTLTSLNIESNFITGTGILALVEALKENDTLTEIKIDNQRQQLG 261
+ + KA A+ LKVN +L LN++ N + G + + AL N L I + Q +G
Sbjct: 986 IGVAGAKALANALKVNSSLRRLNLQENSLGMDGAICIATALSGNHRLQHINL--QGNHIG 1043
Query: 262 TAVEMEIAQMLEENS 276
+ I++ ++ N+
Sbjct: 1044 DSGARMISEAIKTNA 1058
Score = 35.8 bits (81), Expect = 0.051
Identities = 21/68 (30%), Positives = 36/68 (52%), Gaps = 2/68 (2%)
Query: 208 KAFADMLKVNKTLTSLNIESNFITGTGILALVEALKENDTLTEIKIDNQRQQLGTAVEME 267
+A L++N++LTSL+++ N I G A+ ALK N LT + + Q +G +
Sbjct: 908 QALGQALQLNRSLTSLDLQENAIGDDGACAVARALKVNTALTALYL--QVASIGASGAQV 965
Query: 268 IAQMLEEN 275
+ + L N
Sbjct: 966 LGEALAVN 973
Score = 35.8 bits (81), Expect = 0.051
Identities = 33/98 (33%), Positives = 48/98 (48%), Gaps = 4/98 (4%)
Query: 209 AFADMLKVNKTLTSLNIESNFITGTGILALVEALKENDTLTEIKIDNQRQQLGTAVEMEI 268
A A LKVN LT+L ++ I +G L EAL N TL EI +D + +G A +
Sbjct: 937 AVARALKVNTALTALYLQVASIGASGAQVLGEALAVNRTL-EI-LDLRGNAIGVAGAKAL 994
Query: 269 AQMLEENSRILKFGYQFTKQG--PRTRVAAAITKNNDL 304
A L+ NS + + Q G +A A++ N+ L
Sbjct: 995 ANALKVNSSLRRLNLQENSLGMDGAICIATALSGNHRL 1032
Score = 33.5 bits (75), Expect = 0.25
Identities = 30/117 (25%), Positives = 48/117 (41%), Gaps = 4/117 (3%)
Query: 190 QQMKANDPSLQEVNLNNIKAFADMLKVNKTLTSLNIESNFITGTGILALVEALKENDTLT 249
Q +++ D ++ + A L N+TL SL++ N I+ G A+ AL N TL
Sbjct: 806 QGLESLDLQSNSISDAGVAALMGALCTNQTLLSLSLRENSISPEGAQAIAHALCANSTLK 865
Query: 250 EIKIDNQRQQLGTAVEMEIAQMLEENSRI--LKFGYQFTKQGPRTRVAAAITKNNDL 304
+D L IA + EN + L + F + G + A+ N L
Sbjct: 866 --NLDLTANLLHDQGARAIAVAVRENRTLTSLHLQWNFIQAGAAQALGQALQLNRSL 920
>gi|5174617 nucleotide-binding oligomerization domain containing 1
[Homo sapiens]
Length = 953
Score = 46.6 bits (109), Expect = 3e-05
Identities = 29/81 (35%), Positives = 46/81 (56%), Gaps = 6/81 (7%)
Query: 201 EVNLNNIKAFADMLKVNKTLTSLNIESNFITGTGILALVEALKENDTLTEIKIDNQRQQL 260
E+N ++ A+MLKVN+TL L + N IT G L +AL+ N +TEI ++
Sbjct: 879 ELNDEVAESLAEMLKVNQTLKHLWLIQNQITAKGTAQLADALQSNTGITEICLN------ 932
Query: 261 GTAVEMEIAQMLEENSRILKF 281
G ++ E A++ E+ RI+ F
Sbjct: 933 GNLIKPEEAKVYEDEKRIICF 953
>gi|168986655 hypothetical protein LOC145497 [Homo sapiens]
Length = 488
Score = 43.1 bits (100), Expect = 3e-04
Identities = 32/82 (39%), Positives = 40/82 (48%), Gaps = 9/82 (10%)
Query: 202 VNLNN-------IKAFADMLKVNKTLTSLNIESNFITGTGILALVEALKENDTLTEIKID 254
VNLN+ KA A L N +T L +E N I G+L+LVE L+EN L E+ I
Sbjct: 110 VNLNHHGLGPRGTKAIAIALVSNMAVTKLELEDNCIMEEGVLSLVEMLQENYYLQEMNIS 169
Query: 255 NQRQQLGTAVEMEIAQMLEENS 276
N LG I+ E NS
Sbjct: 170 N--NHLGLEGARIISDFFERNS 189
Score = 34.7 bits (78), Expect = 0.11
Identities = 26/85 (30%), Positives = 40/85 (47%), Gaps = 2/85 (2%)
Query: 191 QMKANDPSLQEVNLNNIKAFADMLKVNKTLTSLNIESNFITGTGILALVEALKENDTLTE 250
Q+K D S + + + ML +N LTSL++ N G +AL L+ N TLT
Sbjct: 219 QIKKLDLSHNQFSDVGGEHLGQMLAINVGLTSLDLSWNNFHTRGAVALCNGLRGNVTLT- 277
Query: 251 IKIDNQRQQLGTAVEMEIAQMLEEN 275
K+D G V + + ++L N
Sbjct: 278 -KLDLSMNGFGNEVALALGEVLRLN 301
Score = 29.3 bits (64), Expect = 4.8
Identities = 26/87 (29%), Positives = 39/87 (44%), Gaps = 4/87 (4%)
Query: 196 DPSLQEVNLNNIKAFADMLKVNKTLTSLNIESNFITGTGILALVEALKENDTLTEIKIDN 255
D S + A + L+ N TLT L++ N LAL E L+ N L + +D
Sbjct: 252 DLSWNNFHTRGAVALCNGLRGNVTLTKLDLSMNGFGNEVALALGEVLRLNRCL--VYLDI 309
Query: 256 QRQQLGTAVEMEIAQMLEENS--RILK 280
+G +I++ LE N R+LK
Sbjct: 310 GGNDIGNEGASKISKGLESNESLRVLK 336
>gi|11545912 nucleotide-binding oligomerization domain containing 2
[Homo sapiens]
Length = 1040
Score = 37.7 bits (86), Expect = 0.013
Identities = 33/101 (32%), Positives = 50/101 (49%), Gaps = 11/101 (10%)
Query: 188 SLQQMKANDPSLQEVNL--NNI-----KAFADMLKVNKTLTSLNIESNFITGTGILALVE 240
+L + + SL+ ++L NNI +A A ML N L L +E N + G+ +L E
Sbjct: 918 ALAEALGDHQSLRWLSLVGNNIGSVGAQALALMLAKNVMLEELCLEENHLQDEGVCSLAE 977
Query: 241 ALKENDTLTEIKIDNQ-RQQLGTAVEMEIAQMLEENSRILK 280
LK+N +L +K+ N LG + Q LE N IL+
Sbjct: 978 GLKKNSSLKILKLSNNCITYLGAEA---LLQALERNDTILE 1015
>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
sapiens]
Length = 1935
Score = 37.7 bits (86), Expect = 0.013
Identities = 58/253 (22%), Positives = 109/253 (43%), Gaps = 18/253 (7%)
Query: 67 EHLLMYLEKEALEQKDREDFVPFTGEKKGRVFIPKEKPIETRKEEKVTLDPELEEALASA 126
EHL + + Q++ D G G+ EK + + EK+ L LEEA AS
Sbjct: 1493 EHLETFKRENKNLQEEISDLTEQLGSS-GKTIHELEKVRKQLEAEKMELQSALEEAEASL 1551
Query: 127 SDTELYDLAAVLGVHNL---LNNPKFDEETANNKGGKGPVRNVVKGEKVKPVFEEPPNPT 183
E L A L + + + +++ + + +R V + ++ +
Sbjct: 1552 EHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVV---DSLQTSLDAETRSR 1608
Query: 184 NVEISLQQMKANDPSLQEVNLNNI-KAFADMLKVNKTLTSLNIESNFITGTGILALVEAL 242
N + +++ D + E+ L++ + A+ K K+L SL ++ + L +A+
Sbjct: 1609 NEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQ-------IQLDDAV 1661
Query: 243 KENDTLTE-IKIDNQRQQLGTAVEMEIAQMLEENSRILKFGYQFTKQGPRTRVAAAITKN 301
+ ND L E I I +R L A E+ ++E+ R K Q + RV ++N
Sbjct: 1662 RANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIE-TSERVQLLHSQN 1720
Query: 302 NDLV-RKKRVEAD 313
L+ +KK+++AD
Sbjct: 1721 TSLINQKKKMDAD 1733
>gi|253970456 HIV-1 Tat specific factor 1 [Homo sapiens]
Length = 755
Score = 37.0 bits (84), Expect = 0.023
Identities = 49/220 (22%), Positives = 94/220 (42%), Gaps = 9/220 (4%)
Query: 16 DEDELLGKLSEEELKQL-ENVLDDLDPESAMLPAGFRQKDQTQKAATGPFDREHLLMYLE 74
+ ++ L K SEEE+ E+ DD + ES +D ++K + +RE LE
Sbjct: 520 ESEDDLNKESEEEVGPTKESEEDDSEKES--------DEDCSEKQSEDGSEREFEENGLE 571
Query: 75 KEALEQKDREDFVPFTGEKKGRVFIPKEKPIETRKEEKVTLDPELEEALASASDTELYDL 134
K+ E+ ++ +K+ + E EKV + E SD + +
Sbjct: 572 KDLDEEGSEKELHENVLDKELEENDSENSEFEDDGSEKVLDEEGSEREFDEDSDEKEEEE 631
Query: 135 AAVLGVHNLLNNPKFDEETANNKGGKGPVRNVVKGEKVKPVFEEPPNPTNVEISLQQMKA 194
V + ++ K DEE A+ KG + + +G+ + +FEE + + + ++++
Sbjct: 632 DTYEKVFDDESDEKEDEEYADEKGLEAADKKAEEGDADEKLFEESDDKEDEDADGKEVED 691
Query: 195 NDPSLQEVNLNNIKAFADMLKVNKTLTSLNIESNFITGTG 234
D L E + +N K F + ++ L + E + G G
Sbjct: 692 ADEKLFEDDDSNEKLFDEEEDSSEKLFDDSDERGTLGGFG 731
>gi|21361437 HIV-1 Tat specific factor 1 [Homo sapiens]
Length = 755
Score = 37.0 bits (84), Expect = 0.023
Identities = 49/220 (22%), Positives = 94/220 (42%), Gaps = 9/220 (4%)
Query: 16 DEDELLGKLSEEELKQL-ENVLDDLDPESAMLPAGFRQKDQTQKAATGPFDREHLLMYLE 74
+ ++ L K SEEE+ E+ DD + ES +D ++K + +RE LE
Sbjct: 520 ESEDDLNKESEEEVGPTKESEEDDSEKES--------DEDCSEKQSEDGSEREFEENGLE 571
Query: 75 KEALEQKDREDFVPFTGEKKGRVFIPKEKPIETRKEEKVTLDPELEEALASASDTELYDL 134
K+ E+ ++ +K+ + E EKV + E SD + +
Sbjct: 572 KDLDEEGSEKELHENVLDKELEENDSENSEFEDDGSEKVLDEEGSEREFDEDSDEKEEEE 631
Query: 135 AAVLGVHNLLNNPKFDEETANNKGGKGPVRNVVKGEKVKPVFEEPPNPTNVEISLQQMKA 194
V + ++ K DEE A+ KG + + +G+ + +FEE + + + ++++
Sbjct: 632 DTYEKVFDDESDEKEDEEYADEKGLEAADKKAEEGDADEKLFEESDDKEDEDADGKEVED 691
Query: 195 NDPSLQEVNLNNIKAFADMLKVNKTLTSLNIESNFITGTG 234
D L E + +N K F + ++ L + E + G G
Sbjct: 692 ADEKLFEDDDSNEKLFDEEEDSSEKLFDDSDERGTLGGFG 731
>gi|119703749 hydrocephalus inducing isoform a [Homo sapiens]
Length = 5120
Score = 35.8 bits (81), Expect = 0.051
Identities = 30/125 (24%), Positives = 58/125 (46%), Gaps = 5/125 (4%)
Query: 74 EKEALEQKDREDFVPFTGEKKGRVFIPKEKPIETRKEEKVTLDPELEEALASASDTELYD 133
EK EQ++R+ EK+ + +E+ +EEK+T D +++AL E
Sbjct: 2276 EKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQALRERKKREQER 2335
Query: 134 LAAVLGVHNL---LNNPKFDEETAN--NKGGKGPVRNVVKGEKVKPVFEEPPNPTNVEIS 188
LA + L L K ++E KG +GP++ +K + ++ P T V++
Sbjct: 2336 LAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAANKQVPPLTKVDVK 2395
Query: 189 LQQMK 193
++ ++
Sbjct: 2396 METIE 2400
>gi|149274621 centrosomal protein 78kDa isoform a [Homo sapiens]
Length = 722
Score = 35.4 bits (80), Expect = 0.066
Identities = 23/77 (29%), Positives = 41/77 (53%), Gaps = 1/77 (1%)
Query: 209 AFADMLKVNKTLTSLNIESNFITGTGILALVEALKENDTLTEIKIDNQRQQLGTAVEMEI 268
AFAD L + L +L+++ +T G AL+EAL+ N TL + I + + ++ +
Sbjct: 247 AFADSLSEDLWLRALDLQQCGLTNEGAKALLEALETNTTLVVLDI-RKNPLIDHSMMKAV 305
Query: 269 AQMLEENSRILKFGYQF 285
+ + +N R K YQ+
Sbjct: 306 IKKVLQNGRSAKSEYQW 322
>gi|149274651 centrosomal protein 78kDa isoform b [Homo sapiens]
Length = 706
Score = 35.4 bits (80), Expect = 0.066
Identities = 23/77 (29%), Positives = 41/77 (53%), Gaps = 1/77 (1%)
Query: 209 AFADMLKVNKTLTSLNIESNFITGTGILALVEALKENDTLTEIKIDNQRQQLGTAVEMEI 268
AFAD L + L +L+++ +T G AL+EAL+ N TL + I + + ++ +
Sbjct: 247 AFADSLSEDLWLRALDLQQCGLTNEGAKALLEALETNTTLVVLDI-RKNPLIDHSMMKAV 305
Query: 269 AQMLEENSRILKFGYQF 285
+ + +N R K YQ+
Sbjct: 306 IKKVLQNGRSAKSEYQW 322
>gi|224586773 hypothetical protein LOC643854 [Homo sapiens]
Length = 777
Score = 34.7 bits (78), Expect = 0.11
Identities = 60/308 (19%), Positives = 117/308 (37%), Gaps = 54/308 (17%)
Query: 10 EKYKNIDEDELLGKLSEEELKQLENVLDDLDPESAMLPAGFRQKDQTQKAATGPFDREHL 69
EK K +++ L+ K E E ++E+ L+D E A + +K + + E
Sbjct: 88 EKCKLLEKFSLIQK--EYEGYEVESSLEDASFEKAAAEEARSLEATCEKLSRSNSELEDE 145
Query: 70 LMYLEKEALEQKDREDFVPFTGEKKGRVFIPKEKPIETRKEEKVTLDPELEEALASASDT 129
++ LEK+ E+K + ++ + K I++ ++E +L ++ EA
Sbjct: 146 ILCLEKDLKEEKSKHS-------QQDELMADISKSIQSLEDESKSLKSQIAEAKIICKTF 198
Query: 130 ELYDLAAVLGVHNLLNNPK---------FDEETANNKGGKGPVR---------------- 164
++ + + + + LN F +E KG +
Sbjct: 199 KMSEERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGQVSELNKQKITFEDSKVHAEQV 258
Query: 165 -----NVVKG---------EKVKPVFEEPPNPTNVEISLQQMKANDPSLQEVNLNNIKAF 210
N +K ++ + E+ + N+E+ + N +L + +K
Sbjct: 259 LNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELKVNSQWENGANLDDPPKGALKKL 318
Query: 211 ADMLKVNKTLTSLNIESNFITGTGILALVEALKENDTLTEIKIDNQRQQLGTAVEMEIAQ 270
K+N +L SL E N I I+ L E K + LTE + Q QQ +++ E
Sbjct: 319 IHAAKLNVSLKSLEGERNHI----IIQLSEVDKTKEELTEHIKNLQTQQ--ASLQSENIY 372
Query: 271 MLEENSRI 278
EN ++
Sbjct: 373 FESENQKL 380
>gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens]
Length = 1317
Score = 34.7 bits (78), Expect = 0.11
Identities = 31/124 (25%), Positives = 63/124 (50%), Gaps = 14/124 (11%)
Query: 6 QKELEKYKNIDEDELLGKLSEEELKQLENVLDDLDPESAMLPAGFRQKDQTQKAATGPFD 65
Q+E+E K E+E ++ +EEL++L+ + ++ E + F++ DQ QK D
Sbjct: 687 QQEIELQKKRQEEETFLRV-QEELQRLKELNNNEKAEKFQI---FQELDQLQKEK----D 738
Query: 66 REHLLMYLEKEALEQKDREDFVPFT------GEKKGRVFIPKEKPIETRKEEKVTLDPEL 119
++ + LEK+ LE++++E + EK+ + + + ++ +EEK L+
Sbjct: 739 EQYAKLELEKKRLEEQEKEQVMLVAHLEEQLREKQEMIQLLRRGEVQWVEEEKRDLEGIR 798
Query: 120 EEAL 123
E L
Sbjct: 799 ESLL 802
>gi|194018482 NLR family, pyrin domain containing 4 [Homo sapiens]
Length = 994
Score = 34.3 bits (77), Expect = 0.15
Identities = 25/75 (33%), Positives = 37/75 (49%), Gaps = 8/75 (10%)
Query: 199 LQEVNLNNI--KAFADMLKVNKTLTSLNIESNFITGTGILALVEALKENDT------LTE 250
L+E L + K A +L +KTL LN+ N + TG++ L EAL+ + L +
Sbjct: 900 LEECGLTSTCCKDLASVLTCSKTLQQLNLTLNTLDHTGVVVLCEALRHPECALQVLGLRK 959
Query: 251 IKIDNQRQQLGTAVE 265
D + Q L TA E
Sbjct: 960 TDFDEETQALLTAEE 974
>gi|48255881 troponin T type 2, cardiac isoform 3 [Homo sapiens]
Length = 285
Score = 33.9 bits (76), Expect = 0.19
Identities = 40/197 (20%), Positives = 80/197 (40%), Gaps = 18/197 (9%)
Query: 29 LKQLENVLDDLDPESAMLPAGFRQKDQTQKAATGPFDREHLLMYLEKEALEQKDREDFVP 88
+ +E V+++ + E A Q++ ++ A + E ++E E K+ ED
Sbjct: 1 MSDIEEVVEEYEEEEQEEAAVEEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPM 60
Query: 89 FTGEKKGRVFIPKEKPIETRKEEKVTLDPELEEALASASDTELYDLAAVLGVHNLLNNPK 148
+ K R F+P P + E+V D + + +L +L A++ H N K
Sbjct: 61 EESKPKPRSFMPNLVPPKIPDGERVDFD----DIHRKRMEKDLNELQALIEAH-FENRKK 115
Query: 149 FDEETAN----------NKGGKGPVRNVVKGEKVKPVFEEPPNPTNVEISLQQMKANDPS 198
+EE + + + +RN + E+ + EE E + KA D +
Sbjct: 116 EEEELVSLKDRIERRRAERAEQQRIRNEREKERQNRLAEERARREEEE---NRRKAEDEA 172
Query: 199 LQEVNLNNIKAFADMLK 215
++ L+N+ F ++
Sbjct: 173 RKKKALSNMMHFGGYIQ 189
>gi|48255879 troponin T type 2, cardiac isoform 2 [Homo sapiens]
Length = 288
Score = 33.9 bits (76), Expect = 0.19
Identities = 40/197 (20%), Positives = 80/197 (40%), Gaps = 18/197 (9%)
Query: 29 LKQLENVLDDLDPESAMLPAGFRQKDQTQKAATGPFDREHLLMYLEKEALEQKDREDFVP 88
+ +E V+++ + E A Q++ ++ A + E ++E E K+ ED
Sbjct: 1 MSDIEEVVEEYEEEEQEEAAVEEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPM 60
Query: 89 FTGEKKGRVFIPKEKPIETRKEEKVTLDPELEEALASASDTELYDLAAVLGVHNLLNNPK 148
+ K R F+P P + E+V D + + +L +L A++ H N K
Sbjct: 61 EESKPKPRSFMPNLVPPKIPDGERVDFD----DIHRKRMEKDLNELQALIEAH-FENRKK 115
Query: 149 FDEETAN----------NKGGKGPVRNVVKGEKVKPVFEEPPNPTNVEISLQQMKANDPS 198
+EE + + + +RN + E+ + EE E + KA D +
Sbjct: 116 EEEELVSLKDRIERRRAERAEQQRIRNEREKERQNRLAEERARREEEE---NRRKAEDEA 172
Query: 199 LQEVNLNNIKAFADMLK 215
++ L+N+ F ++
Sbjct: 173 RKKKALSNMMHFGGYIQ 189
>gi|33667040 NLR family, pyrin domain containing 8 [Homo sapiens]
Length = 1048
Score = 33.9 bits (76), Expect = 0.19
Identities = 33/116 (28%), Positives = 56/116 (48%), Gaps = 11/116 (9%)
Query: 165 NVVKGEKVKPVFEEPPNPTNVEISLQQMKANDPSLQEVNLNNIKAFADMLKVNKTLTSLN 224
N +K E K ++ P+ + LQ++ L N + L NKTL SL+
Sbjct: 877 NALKDEGAKHIWNALPH---LRCPLQRLVLRKCDL---TFNCCQDMISALCKNKTLKSLD 930
Query: 225 IESNFITGTGILALVEALKEND-TLTEIKIDNQRQQLGTAVEME-IAQMLEENSRI 278
+ N + G++ L EALK D TL ++++N L T++ + +A ML +N +
Sbjct: 931 LSFNSLKDDGVILLCEALKNPDCTLQILELEN---CLFTSICCQAMASMLRKNQHL 983
Score = 30.8 bits (68), Expect = 1.6
Identities = 22/69 (31%), Positives = 32/69 (46%), Gaps = 7/69 (10%)
Query: 190 QQMKANDPSLQEVNLNNI-------KAFADMLKVNKTLTSLNIESNFITGTGILALVEAL 242
+ +K D +LQ + L N +A A ML+ N+ L L++ N I GIL L EA
Sbjct: 946 EALKNPDCTLQILELENCLFTSICCQAMASMLRKNQHLRHLDLSKNAIGVYGILTLCEAF 1005
Query: 243 KENDTLTEI 251
E+
Sbjct: 1006 SSQKKREEV 1014
>gi|229577123 t-complex-associated testis expressed 1 [Homo sapiens]
Length = 501
Score = 33.5 bits (75), Expect = 0.25
Identities = 24/103 (23%), Positives = 48/103 (46%), Gaps = 4/103 (3%)
Query: 208 KAFADMLKVNKTLTSLNIESNFITGTGILALVEALKENDTLTEIKIDNQRQQLGTAVEME 267
+A A L+ NK LT+L++ N ++ L + L N TLT I + +G +
Sbjct: 380 QALAHALQTNKCLTTLHLGGNELSEPTATLLSQVLAINTTLTSINL--SCNHIGLDGGKQ 437
Query: 268 IAQMLEENSRILKFGYQFT--KQGPRTRVAAAITKNNDLVRKK 308
+ + + +N +L+F + + Q + A+ N + R++
Sbjct: 438 LLEGMSDNKTLLEFDLRLSDVAQESEYLIGQALYANREAARQR 480
>gi|133908641 myosin binding protein C, fast type [Homo sapiens]
Length = 1141
Score = 33.5 bits (75), Expect = 0.25
Identities = 46/224 (20%), Positives = 100/224 (44%), Gaps = 23/224 (10%)
Query: 79 EQKDREDFVPFTGEKKGRVFIPKEKPIETRKEEKVTLDPELEEALASASDTELYDLAAVL 138
++ D + F+G K R + +EK + + ++ + + PE+ E L A +E +A
Sbjct: 174 KKSDTAGELDFSGLLKKREVVEEEKKKKKKDDDDLGIPPEIWELLKGAKKSEYEKIAFQY 233
Query: 139 GVHNL------LNNPKFD-EETANNKGGKGPVRNVVKGEKVKPVFEEPPNPTNVEISLQQ 191
G+ +L L K + +++A P V +G K+K + E ++ +++L+
Sbjct: 234 GITDLRGMLKRLKKAKVEVKKSAAFTKKLDPAYQVDRGNKIKLMVE----ISDPDLTLKW 289
Query: 192 MKANDPSLQEVNLNNIKAFAD-----MLKVNKTLTSLNIESNFITGTGILALVEALKEND 246
K QE+ ++ F + +L +NK + + +KE
Sbjct: 290 FKNG----QEIKPSSKYVFENVGKKRILTINKCTLADDAAYEVAVKDEKCFTELFVKEPP 345
Query: 247 TLTEIKIDNQRQQLGTAVEMEIAQMLEENSRI--LKFGYQFTKQ 288
L +++Q+ +G VEM + ++ EE +++ +K G + T++
Sbjct: 346 VLIVTPLEDQQVFVGDRVEMAV-EVSEEGAQVMWMKDGVELTRE 388
>gi|193290160 CTAGE family, member 4 [Homo sapiens]
Length = 777
Score = 33.1 bits (74), Expect = 0.33
Identities = 60/308 (19%), Positives = 116/308 (37%), Gaps = 54/308 (17%)
Query: 10 EKYKNIDEDELLGKLSEEELKQLENVLDDLDPESAMLPAGFRQKDQTQKAATGPFDREHL 69
EK K +++ L+ K E E ++E+ L+D E A + +K + E
Sbjct: 88 EKCKLLEKFSLIQK--EYEGYEVESSLEDASFEKAAAEEARSLEATCEKLNRSNSELEDE 145
Query: 70 LMYLEKEALEQKDREDFVPFTGEKKGRVFIPKEKPIETRKEEKVTLDPELEEALASASDT 129
++ LEK+ E+K + ++ + K I++ ++E +L ++ EA
Sbjct: 146 ILCLEKDLKEEKSKHS-------QQDELMADISKSIQSLEDESKSLKSQIAEAKIICKTF 198
Query: 130 ELYDLAAVLGVHNLLNNPK---------FDEETANNKGGKGPVR---------------- 164
++ + + + + LN F +E KG +
Sbjct: 199 KMSEERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGEVSELNKQKITFEDSKVHAEQV 258
Query: 165 -----NVVKG---------EKVKPVFEEPPNPTNVEISLQQMKANDPSLQEVNLNNIKAF 210
N +K ++ + E+ + N+E+ + N +L + +K
Sbjct: 259 LNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELEVNSQWENGANLDDPLKGALKKL 318
Query: 211 ADMLKVNKTLTSLNIESNFITGTGILALVEALKENDTLTEIKIDNQRQQLGTAVEMEIAQ 270
K+N +L SL E N I I+ L E K + LTE + Q QQ +++ E
Sbjct: 319 IHAAKLNVSLKSLEGERNHI----IIQLSEVDKTKEELTEHIKNLQTQQ--ASLQSENIY 372
Query: 271 MLEENSRI 278
EN ++
Sbjct: 373 FESENQKL 380
>gi|22538457 nuclear receptor coactivator 1 isoform 2 [Homo sapiens]
Length = 1399
Score = 33.1 bits (74), Expect = 0.33
Identities = 45/193 (23%), Positives = 73/193 (37%), Gaps = 40/193 (20%)
Query: 28 ELKQLENVLDDLDPESAMLPAGFRQKDQTQKAATGPFDREHLLMYLEKEALE----QKDR 83
E +++ + + +S +LPA Q A P R + L LE EA++ Q
Sbjct: 832 ETDRMDGAVTSVTIKSEILPASL------QSATARPTSRLNRLPELELEAIDNQFGQPGT 885
Query: 84 EDFVPFTGEKKGRVFIPKEKP----------------IETRKEEKVTLDPELEEALASAS 127
D +P+T + K + +E R +EK L+ +L L+
Sbjct: 886 GDQIPWTNNTVTAINQSKSEDQCISSQLDELLCPPTTVEGRNDEKALLE-QLVSFLSGKD 944
Query: 128 DTELYDLAAVLGVHNLLNNPKFDEETANNKGGKGPVRNVVKGEKVKP--VFEEPPNPTNV 185
+TEL +L LG+ L+ GG + ++ P + EE PN +
Sbjct: 945 ETELAELDRALGIDKLVQG-----------GGLDVLSERFPPQQATPPLIMEERPNLYSQ 993
Query: 186 EISLQQMKANDPS 198
S AN PS
Sbjct: 994 PYSSPSPTANLPS 1006
>gi|22538459 nuclear receptor coactivator 1 isoform 3 [Homo sapiens]
Length = 1440
Score = 33.1 bits (74), Expect = 0.33
Identities = 45/193 (23%), Positives = 73/193 (37%), Gaps = 40/193 (20%)
Query: 28 ELKQLENVLDDLDPESAMLPAGFRQKDQTQKAATGPFDREHLLMYLEKEALE----QKDR 83
E +++ + + +S +LPA Q A P R + L LE EA++ Q
Sbjct: 832 ETDRMDGAVTSVTIKSEILPASL------QSATARPTSRLNRLPELELEAIDNQFGQPGT 885
Query: 84 EDFVPFTGEKKGRVFIPKEKP----------------IETRKEEKVTLDPELEEALASAS 127
D +P+T + K + +E R +EK L+ +L L+
Sbjct: 886 GDQIPWTNNTVTAINQSKSEDQCISSQLDELLCPPTTVEGRNDEKALLE-QLVSFLSGKD 944
Query: 128 DTELYDLAAVLGVHNLLNNPKFDEETANNKGGKGPVRNVVKGEKVKP--VFEEPPNPTNV 185
+TEL +L LG+ L+ GG + ++ P + EE PN +
Sbjct: 945 ETELAELDRALGIDKLVQG-----------GGLDVLSERFPPQQATPPLIMEERPNLYSQ 993
Query: 186 EISLQQMKANDPS 198
S AN PS
Sbjct: 994 PYSSPSPTANLPS 1006
>gi|22538455 nuclear receptor coactivator 1 isoform 1 [Homo sapiens]
Length = 1441
Score = 33.1 bits (74), Expect = 0.33
Identities = 45/193 (23%), Positives = 73/193 (37%), Gaps = 40/193 (20%)
Query: 28 ELKQLENVLDDLDPESAMLPAGFRQKDQTQKAATGPFDREHLLMYLEKEALE----QKDR 83
E +++ + + +S +LPA Q A P R + L LE EA++ Q
Sbjct: 832 ETDRMDGAVTSVTIKSEILPASL------QSATARPTSRLNRLPELELEAIDNQFGQPGT 885
Query: 84 EDFVPFTGEKKGRVFIPKEKP----------------IETRKEEKVTLDPELEEALASAS 127
D +P+T + K + +E R +EK L+ +L L+
Sbjct: 886 GDQIPWTNNTVTAINQSKSEDQCISSQLDELLCPPTTVEGRNDEKALLE-QLVSFLSGKD 944
Query: 128 DTELYDLAAVLGVHNLLNNPKFDEETANNKGGKGPVRNVVKGEKVKP--VFEEPPNPTNV 185
+TEL +L LG+ L+ GG + ++ P + EE PN +
Sbjct: 945 ETELAELDRALGIDKLVQG-----------GGLDVLSERFPPQQATPPLIMEERPNLYSQ 993
Query: 186 EISLQQMKANDPS 198
S AN PS
Sbjct: 994 PYSSPSPTANLPS 1006
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.131 0.351
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,581,359
Number of Sequences: 37866
Number of extensions: 541324
Number of successful extensions: 1943
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 40
Number of HSP's successfully gapped in prelim test: 84
Number of HSP's that attempted gapping in prelim test: 1817
Number of HSP's gapped (non-prelim): 193
length of query: 315
length of database: 18,247,518
effective HSP length: 102
effective length of query: 213
effective length of database: 14,385,186
effective search space: 3064044618
effective search space used: 3064044618
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.