Guide to the Human Genome
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Search of human proteins with 218751874

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|218751874 hairy and enhancer of split 6 isoform b [Homo
sapiens]
         (222 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|218751874 hairy and enhancer of split 6 isoform b [Homo sapiens]   447   e-126
gi|21361763 hairy and enhancer of split 6 isoform a [Homo sapiens]    442   e-124
gi|5031763 hairy and enhancer of split 1 [Homo sapiens]                99   3e-21
gi|216548627 hairy and enhancer of split 4 isoform 1 [Homo sapiens]    89   3e-18
gi|10863967 hairy and enhancer of split 4 isoform 2 [Homo sapiens]     89   3e-18
gi|63055047 hairy and enhancer of split homolog 2 [Homo sapiens]       77   2e-14
gi|105990528 hairy/enhancer-of-split related with YRPW motif 1 i...    65   6e-11
gi|105990526 hairy/enhancer-of-split related with YRPW motif 1 i...    63   2e-10
gi|6912414 hairy/enhancer-of-split related with YRPW motif 2 [Ho...    63   2e-10
gi|145207994 hairy and enhancer of split 7 [Homo sapiens]              56   2e-08
gi|7657154 hairy/enhancer-of-split related with YRPW motif-like ...    52   5e-07
gi|58219048 hairy and enhancer of split 5 [Homo sapiens]               52   5e-07
gi|71274142 HES/HEY-like transcription factor [Homo sapiens]           52   5e-07
gi|66912172 hairy and enhancer of split 3 [Homo sapiens]               48   8e-06
gi|4503299 basic helix-loop-helix family, member e40 [Homo sapiens]    47   1e-05
gi|13540521 basic helix-loop-helix domain containing, class B, 3...    42   5e-04
gi|52630419 sterol regulatory element binding transcription fact...    40   0.001
gi|22547195 sterol regulatory element binding transcription fact...    40   0.001
gi|110556636 tankyrase 1-binding protein 1 [Homo sapiens]              37   0.013
gi|116008152 alpha 1 type XV collagen precursor [Homo sapiens]         36   0.023
gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]       36   0.030
gi|6912492 mitogen-activated protein kinase 8 interacting protei...    36   0.030
gi|7706537 mitogen-activated protein kinase 8 interacting protei...    36   0.030
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    35   0.039
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    35   0.039
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    35   0.039
gi|154355000 KH-type splicing regulatory protein [Homo sapiens]        35   0.039
gi|27477113 sterol regulatory element-binding transcription fact...    35   0.039
gi|110556644 zinc finger protein, multitype 1 [Homo sapiens]           35   0.039
gi|169207312 PREDICTED: hypothetical protein [Homo sapiens]            35   0.051

>gi|218751874 hairy and enhancer of split 6 isoform b [Homo sapiens]
          Length = 222

 Score =  447 bits (1149), Expect = e-126
 Identities = 222/222 (100%), Positives = 222/222 (100%)

Query: 1   MAPPAAPGRDRVGREDEDGWETRGDRKARKPLVEKKRRARINESLQELRLLLAGAEAKLE 60
           MAPPAAPGRDRVGREDEDGWETRGDRKARKPLVEKKRRARINESLQELRLLLAGAEAKLE
Sbjct: 1   MAPPAAPGRDRVGREDEDGWETRGDRKARKPLVEKKRRARINESLQELRLLLAGAEAKLE 60

Query: 61  NAEVLELTVRRVQGVLRGRAREREQLQAEASERFAAGYIQCMHEVHTFVSTCQAIDATVA 120
           NAEVLELTVRRVQGVLRGRAREREQLQAEASERFAAGYIQCMHEVHTFVSTCQAIDATVA
Sbjct: 61  NAEVLELTVRRVQGVLRGRAREREQLQAEASERFAAGYIQCMHEVHTFVSTCQAIDATVA 120

Query: 121 AELLNHLLESMPLREGSSFQDLLGDALAGPPRAPGRSGWPAGGAPGSPIPSPPGPGDDLC 180
           AELLNHLLESMPLREGSSFQDLLGDALAGPPRAPGRSGWPAGGAPGSPIPSPPGPGDDLC
Sbjct: 121 AELLNHLLESMPLREGSSFQDLLGDALAGPPRAPGRSGWPAGGAPGSPIPSPPGPGDDLC 180

Query: 181 SDLEEAPEAELSQAPAEGPDLVPAALGSLTTAQIARSVWRPW 222
           SDLEEAPEAELSQAPAEGPDLVPAALGSLTTAQIARSVWRPW
Sbjct: 181 SDLEEAPEAELSQAPAEGPDLVPAALGSLTTAQIARSVWRPW 222


>gi|21361763 hairy and enhancer of split 6 isoform a [Homo sapiens]
          Length = 224

 Score =  442 bits (1136), Expect = e-124
 Identities = 222/224 (99%), Positives = 222/224 (99%), Gaps = 2/224 (0%)

Query: 1   MAPPAAPGRDRVGREDEDGWETRGDRKARKPLVEKKRRARINESLQELRLLLAGAE--AK 58
           MAPPAAPGRDRVGREDEDGWETRGDRKARKPLVEKKRRARINESLQELRLLLAGAE  AK
Sbjct: 1   MAPPAAPGRDRVGREDEDGWETRGDRKARKPLVEKKRRARINESLQELRLLLAGAEVQAK 60

Query: 59  LENAEVLELTVRRVQGVLRGRAREREQLQAEASERFAAGYIQCMHEVHTFVSTCQAIDAT 118
           LENAEVLELTVRRVQGVLRGRAREREQLQAEASERFAAGYIQCMHEVHTFVSTCQAIDAT
Sbjct: 61  LENAEVLELTVRRVQGVLRGRAREREQLQAEASERFAAGYIQCMHEVHTFVSTCQAIDAT 120

Query: 119 VAAELLNHLLESMPLREGSSFQDLLGDALAGPPRAPGRSGWPAGGAPGSPIPSPPGPGDD 178
           VAAELLNHLLESMPLREGSSFQDLLGDALAGPPRAPGRSGWPAGGAPGSPIPSPPGPGDD
Sbjct: 121 VAAELLNHLLESMPLREGSSFQDLLGDALAGPPRAPGRSGWPAGGAPGSPIPSPPGPGDD 180

Query: 179 LCSDLEEAPEAELSQAPAEGPDLVPAALGSLTTAQIARSVWRPW 222
           LCSDLEEAPEAELSQAPAEGPDLVPAALGSLTTAQIARSVWRPW
Sbjct: 181 LCSDLEEAPEAELSQAPAEGPDLVPAALGSLTTAQIARSVWRPW 224


>gi|5031763 hairy and enhancer of split 1 [Homo sapiens]
          Length = 280

 Score = 99.0 bits (245), Expect = 3e-21
 Identities = 75/247 (30%), Positives = 110/247 (44%), Gaps = 53/247 (21%)

Query: 26  RKARKPLVEKKRRARINESLQELRLLLAGA-------EAKLENAEVLELTVRRVQGVLRG 78
           RK+ KP++EK+RRARINESL +L+ L+  A        +KLE A++LE+TV+ ++ + R 
Sbjct: 35  RKSSKPIMEKRRRARINESLSQLKTLILDALKKDSSRHSKLEKADILEMTVKHLRNLQRA 94

Query: 79  RAREREQLQAEASERFAAGYIQCMHEVHTFVSTCQAIDATVAAELLNHLLESMPLREGSS 138
           +             ++ AG+ +CM+EV  F+STC+ ++  V   LL HL   M      +
Sbjct: 95  QMTAALSTDPSVLGKYRAGFSECMNEVTRFLSTCEGVNTEVRTRLLGHLANCMTQINAMT 154

Query: 139 FQDLLGDALAGPPRAPGRSGWP-----AGGAPGSPIP--SPPGPGDDLCSDLEEAPEA-- 189
           +      AL  PP  P   G P     A   P  PIP  + P PG   C    +A EA  
Sbjct: 155 YPGQPHPALQAPPPPPPGPGGPQHAPFAPPPPLVPIPGGAAPPPGGAPCKLGSQAGEAAK 214

Query: 190 -----ELSQAP-----------------------------AEGPDLVPAALGSLTTAQIA 215
                ++  AP                             + GP+ V  + G   TA   
Sbjct: 215 VFGGFQVVPAPDGQFAFLIPNGAFAHSGPVIPVYTSNSGTSVGPNAVSPSSGPSLTAD-- 272

Query: 216 RSVWRPW 222
            S+WRPW
Sbjct: 273 -SMWRPW 278


>gi|216548627 hairy and enhancer of split 4 isoform 1 [Homo sapiens]
          Length = 247

 Score = 89.0 bits (219), Expect = 3e-18
 Identities = 69/228 (30%), Positives = 102/228 (44%), Gaps = 35/228 (15%)

Query: 7   PG-RDRVGREDEDGWETRGDRKARKPLVEKKRRARINESLQELRLLLAGA-------EAK 58
           PG R   G  +  G +   D ++ KP++EK+RRARINESL +L+ L+  A        +K
Sbjct: 41  PGVRGATGGREGRGTQPVPDPQSSKPVMEKRRRARINESLAQLKTLILDALRKESSRHSK 100

Query: 59  LENAEVLELTVRRVQGVLRGRAREREQLQAEASERFAAGYIQCMHEVHTFVSTCQAIDAT 118
           LE A++LE+TVR ++ + R +             ++ AG+ +C+ EV+ F++ C+ + A 
Sbjct: 101 LEKADILEMTVRHLRSLRRVQVTAALSADPAVLGKYRAGFHECLAEVNRFLAGCEGVPAD 160

Query: 119 VAAELLNHLLESM----PLREGSSFQDLLGDALAGPPRAPGRSGWPAGGAPGSPIPSPPG 174
           V + LL HL   +    P R  +S            P AP  +  P   A    +PS  G
Sbjct: 161 VRSRLLGHLAACLRQLGPSRRPASLS----------PAAPAEAPAPEVYAGRPLLPSLGG 210

Query: 175 PGDDLCSDLEEAPEAELSQAPAEGPDLVPAALGSLTTAQIARSVWRPW 222
           P   L   L       L  AP  GP             Q     WRPW
Sbjct: 211 PFPLLAPPLLPGLTRALPAAPRAGP-------------QGPGGPWRPW 245


>gi|10863967 hairy and enhancer of split 4 isoform 2 [Homo sapiens]
          Length = 221

 Score = 89.0 bits (219), Expect = 3e-18
 Identities = 69/232 (29%), Positives = 100/232 (43%), Gaps = 34/232 (14%)

Query: 2   APPAAPGRDRVGREDEDGWETRGDRKARKPLVEKKRRARINESLQELRLLLAGA------ 55
           A P A       R  +        RK+ KP++EK+RRARINESL +L+ L+  A      
Sbjct: 11  ASPMAGAPASASRTPDKPRSAAEHRKSSKPVMEKRRRARINESLAQLKTLILDALRKESS 70

Query: 56  -EAKLENAEVLELTVRRVQGVLRGRAREREQLQAEASERFAAGYIQCMHEVHTFVSTCQA 114
             +KLE A++LE+TVR ++ + R +             ++ AG+ +C+ EV+ F++ C+ 
Sbjct: 71  RHSKLEKADILEMTVRHLRSLRRVQVTAALSADPAVLGKYRAGFHECLAEVNRFLAGCEG 130

Query: 115 IDATVAAELLNHLLESM----PLREGSSFQDLLGDALAGPPRAPGRSGWPAGGAPGSPIP 170
           + A V + LL HL   +    P R  +S            P AP  +  P   A    +P
Sbjct: 131 VPADVRSRLLGHLAACLRQLGPSRRPASLS----------PAAPAEAPAPEVYAGRPLLP 180

Query: 171 SPPGPGDDLCSDLEEAPEAELSQAPAEGPDLVPAALGSLTTAQIARSVWRPW 222
           S  GP   L   L       L  AP  GP             Q     WRPW
Sbjct: 181 SLGGPFPLLAPPLLPGLTRALPAAPRAGP-------------QGPGGPWRPW 219


>gi|63055047 hairy and enhancer of split homolog 2 [Homo sapiens]
          Length = 173

 Score = 76.6 bits (187), Expect = 2e-14
 Identities = 56/159 (35%), Positives = 83/159 (52%), Gaps = 18/159 (11%)

Query: 26  RKARKPLVEKKRRARINESLQELR---LLLAGAE----AKLENAEVLELTVRRVQGVLRG 78
           RK+ KPL+EK+RRARIN+SL +L+   L L G E    +KLE A+VLE+TVR +Q +   
Sbjct: 14  RKSLKPLLEKRRRARINQSLSQLKGLILPLLGRENSNCSKLEKADVLEMTVRFLQELPAS 73

Query: 79  RAREREQLQAEASERFAAGYIQCMHEVHTFVSTCQAIDATVAAELLNHLLE--SMPLREG 136
                  L  ++   +  GY  C+  +   +  C+ ++  V+A LL HL    +    +G
Sbjct: 74  SWPTAAPLPCDS---YREGYSACVARLARVLPACRVLEPAVSARLLEHLWRRAASATLDG 130

Query: 137 SSFQDLLGDALAGPPRAPGRSGWPAGGAPGSPIPSPPGP 175
               D  G +   P  AP  +  PA     +P+PSPP P
Sbjct: 131 GRAGDSSGPSAPAP--APASAPEPA----SAPVPSPPSP 163


>gi|105990528 hairy/enhancer-of-split related with YRPW motif 1
           isoform a [Homo sapiens]
          Length = 304

 Score = 64.7 bits (156), Expect = 6e-11
 Identities = 58/194 (29%), Positives = 88/194 (45%), Gaps = 16/194 (8%)

Query: 26  RKARKPLVEKKRRARINESLQELRLLLAGA-----EAKLENAEVLELTVRRVQGVLRGRA 80
           RK R+ ++EK+RR RIN SL ELR L+  A      AKLE AE+L++TV  ++ +     
Sbjct: 50  RKRRRGIIEKRRRDRINNSLSELRRLVPSAFEKQGSAKLEKAEILQMTVDHLKMLHTAGG 109

Query: 81  REREQLQAEASERFAAGYIQCMHEVHTFVSTCQAIDAT--VAAELLNHLLESMPLREGSS 138
           +      A A +  + G+ +C+ EV  ++S  + +DA+  +   L++HL      RE +S
Sbjct: 110 KGYFDAHALAMDYRSLGFRECLAEVARYLSIIEGLDASDPLRVRLVSHLNNYASQREAAS 169

Query: 139 FQDLLGDALAGPPRAPGRSGWPAGGAPGSPIPSPP---GPGDDLCSDLEEAPEAELSQAP 195
                  A AG    P  + +        P+  P    G      S  E   +  L  A 
Sbjct: 170 ------GAHAGLGHIPWGTVFGHHPHIAHPLLLPQNGHGNAGTTASPTEPHHQGRLGSAH 223

Query: 196 AEGPDLVPAALGSL 209
            E P L     GSL
Sbjct: 224 PEAPALRAPPSGSL 237


>gi|105990526 hairy/enhancer-of-split related with YRPW motif 1
           isoform b [Homo sapiens]
          Length = 308

 Score = 63.2 bits (152), Expect = 2e-10
 Identities = 58/198 (29%), Positives = 88/198 (44%), Gaps = 20/198 (10%)

Query: 26  RKARKPLVEKKRRARINESLQELRLLLAGA---------EAKLENAEVLELTVRRVQGVL 76
           RK R+ ++EK+RR RIN SL ELR L+  A          AKLE AE+L++TV  ++ + 
Sbjct: 50  RKRRRGIIEKRRRDRINNSLSELRRLVPSAFEKQVMEQGSAKLEKAEILQMTVDHLKMLH 109

Query: 77  RGRAREREQLQAEASERFAAGYIQCMHEVHTFVSTCQAIDAT--VAAELLNHLLESMPLR 134
               +      A A +  + G+ +C+ EV  ++S  + +DA+  +   L++HL      R
Sbjct: 110 TAGGKGYFDAHALAMDYRSLGFRECLAEVARYLSIIEGLDASDPLRVRLVSHLNNYASQR 169

Query: 135 EGSSFQDLLGDALAGPPRAPGRSGWPAGGAPGSPIPSPP---GPGDDLCSDLEEAPEAEL 191
           E +S       A AG    P  + +        P+  P    G      S  E   +  L
Sbjct: 170 EAAS------GAHAGLGHIPWGTVFGHHPHIAHPLLLPQNGHGNAGTTASPTEPHHQGRL 223

Query: 192 SQAPAEGPDLVPAALGSL 209
             A  E P L     GSL
Sbjct: 224 GSAHPEAPALRAPPSGSL 241


>gi|6912414 hairy/enhancer-of-split related with YRPW motif 2 [Homo
           sapiens]
          Length = 337

 Score = 62.8 bits (151), Expect = 2e-10
 Identities = 39/120 (32%), Positives = 68/120 (56%), Gaps = 7/120 (5%)

Query: 26  RKARKPLVEKKRRARINESLQELRLLLAGA-----EAKLENAEVLELTVRRVQGVLRGRA 80
           RK R+ ++EK+RR RIN SL ELR L+  A      AKLE AE+L++TV  ++ +     
Sbjct: 49  RKKRRGIIEKRRRDRINNSLSELRRLVPTAFEKQGSAKLEKAEILQMTVDHLKMLQATGG 108

Query: 81  REREQLQAEASERFAAGYIQCMHEVHTFVSTCQAIDAT--VAAELLNHLLESMPLREGSS 138
           +      A A +  + G+ +C+ EV  ++S+ + +D++  +   L++HL      RE ++
Sbjct: 109 KGYFDAHALAMDFMSIGFRECLTEVARYLSSVEGLDSSDPLRVRLVSHLSTCATQREAAA 168


>gi|145207994 hairy and enhancer of split 7 [Homo sapiens]
          Length = 225

 Score = 56.2 bits (134), Expect = 2e-08
 Identities = 75/250 (30%), Positives = 92/250 (36%), Gaps = 75/250 (30%)

Query: 18  DGWETRGDRKARKPLVEKKRRARINESLQELRLLLAG-------AEAKLENAEVLELTVR 70
           D  E R   K  KPLVEK+RR RIN SL+ELRLLL            KLE AE+LE  V 
Sbjct: 5   DRAENRDGPKMLKPLVEKRRRDRINRSLEELRLLLLERTRDQNLRNPKLEKAEILEFAV- 63

Query: 71  RVQGVLRGRAR------EREQLQ-AEA-SERFAAGYIQCMHEVHTFVSTCQAIDATVAAE 122
              G LR R+R       R  +Q AEA +  + +G+ +C+  +  F              
Sbjct: 64  ---GYLRERSRVEPPGVPRSPVQDAEALASCYLSGFRECLLRLAAFAHDASPAARAQLFS 120

Query: 123 LLNHLLESMPLREG-------------SSFQDLLGDAL-AGPPRAPG----RSGW----- 159
            L+  L   P R                     LG AL   PP   G    R  W     
Sbjct: 121 ALHGYLRPKPPRPKPVDPRPPAPRPSLDPAAPALGPALHQRPPVHQGHPSPRCAWSPSLC 180

Query: 160 -PAGGAPGSP------IPSPPGPGDDLCSDLEEAPEAELSQAPAEGPDLVPAALGSLTTA 212
            P  G  G+P      +P PP P        + AP+A L   PA                
Sbjct: 181 SPRAGDSGAPAPLTGLLPPPPPPHRQ-----DGAPKAPLPPPPA---------------- 219

Query: 213 QIARSVWRPW 222
                 WRPW
Sbjct: 220 -----FWRPW 224


>gi|7657154 hairy/enhancer-of-split related with YRPW motif-like
           [Homo sapiens]
          Length = 328

 Score = 51.6 bits (122), Expect = 5e-07
 Identities = 37/110 (33%), Positives = 59/110 (53%), Gaps = 8/110 (7%)

Query: 26  RKARKPLVEKKRRARINESLQELRLLLAGA-----EAKLENAEVLELTVRRVQGVLRGRA 80
           RK R+ ++EK+RR RIN SL ELR L+  A      +KLE AEVL++TV  ++ +     
Sbjct: 44  RKKRRGIIEKRRRDRINSSLSELRRLVPTAFEKQGSSKLEKAEVLQMTVDHLKMLHATGG 103

Query: 81  REREQLQAEASERFAAGYIQCMHEVHTFVSTCQAIDA---TVAAELLNHL 127
                 +A A +  + G+ +C+ EV  ++   +   +    V   LL+HL
Sbjct: 104 TGFFDARALAVDFRSIGFRECLTEVIRYLGVLEGPSSRADPVRIRLLSHL 153


>gi|58219048 hairy and enhancer of split 5 [Homo sapiens]
          Length = 166

 Score = 51.6 bits (122), Expect = 5e-07
 Identities = 55/202 (27%), Positives = 79/202 (39%), Gaps = 59/202 (29%)

Query: 27  KARKPLVEKKRRARINESLQELRLLLA------GAEAKLENAEVLELTVRRVQGVLRGRA 80
           + RKP+VEK RR RIN S+++L+LLL          +KLE A++LE+ V  ++     +A
Sbjct: 18  RLRKPVVEKMRRDRINSSIEQLKLLLEQEFARHQPNSKLEKADILEMAVSYLK---HSKA 74

Query: 81  REREQLQAEASERFAAGYIQCMHEVHTFVSTCQAIDATVAAELLNHLLESMPLREGSSFQ 140
                      + ++ GY  C+ E   F++   A D  +  +LL H            FQ
Sbjct: 75  FVAAAGPKSLHQDYSEGYSWCLQEAVQFLTLHAASDTQM--KLLYH------------FQ 120

Query: 141 DLLGDALAGPPRAPGRSGWPAGGAPGSPIPSPPGPGDDLCSDLEEAPEAELSQAPAEGPD 200
                    PP            AP +P   P  PG         AP   LS        
Sbjct: 121 --------RPP-----------AAPAAPAKEPKAPG--------AAPPPALS-------- 145

Query: 201 LVPAALGSLTTAQIARSVWRPW 222
              A   +    Q A  +WRPW
Sbjct: 146 -AKATAAAAAAHQPACGLWRPW 166


>gi|71274142 HES/HEY-like transcription factor [Homo sapiens]
          Length = 327

 Score = 51.6 bits (122), Expect = 5e-07
 Identities = 49/173 (28%), Positives = 73/173 (42%), Gaps = 22/173 (12%)

Query: 51  LLAGAEAKLENAEVLELTVRRVQGVLRG---RAREREQLQAEASERFAAGYIQCMHEVHT 107
           LL  +  KLE AE+LE+TV+ ++ +      R RE+ +L AE +  F  GY +CM  +  
Sbjct: 126 LLLQSSGKLEKAEILEMTVQYLRALHSADFPRGREKAELLAEFANYFHYGYHECMKNLVH 185

Query: 108 FVSTCQAID----------------ATVAAELLNHLLESMPLREGSSFQDLLGDALAGPP 151
           +++T + ++                A + AE     L S+P  + S      G   AG  
Sbjct: 186 YLTTVERMETKDTKYARILAFLQSKARLGAEPAFPPLGSLPEPDFSYQLHPAGPEFAG-- 243

Query: 152 RAPGRSGWPAGGAPGSPIPSPPGPG-DDLCSDLEEAPEAELSQAPAEGPDLVP 203
            +PG +     G+   P P PPG         L  AP    S A    P L P
Sbjct: 244 HSPGEAAVFPQGSGAGPFPWPPGAARSPALPYLPSAPVPLASPAQQHSPFLTP 296


>gi|66912172 hairy and enhancer of split 3 [Homo sapiens]
          Length = 186

 Score = 47.8 bits (112), Expect = 8e-06
 Identities = 57/202 (28%), Positives = 83/202 (41%), Gaps = 36/202 (17%)

Query: 33  VEKKRRARINESLQELRLLLAG------AEAKLENAEVLELTV---RRVQGVLRGR---A 80
           +EKKRRARIN SL++L+ LL         + KLE A++LEL+V   R +Q  L+G     
Sbjct: 1   MEKKRRARINVSLEQLKSLLEKHYSHQIRKRKLEKADILELSVKYMRSLQNSLQGLWPVP 60

Query: 81  REREQLQAEASERFAAGYIQCMHEVHTFVSTCQAIDATVAAELLNHLLESMPLREGSSFQ 140
           R  EQ          +G+  C+  V   +     + + +   L+        +      Q
Sbjct: 61  RGAEQ---------PSGFRSCLPGVSQLLRRGDEVGSGLRCPLVPESAAGSTMDSAGLGQ 111

Query: 141 DLLGDALAGPPRAPGRSGWPAGGAPGSPIPSPPGPGDDLCSDLEEAPEAELSQAPAEGPD 200
           +    AL  P      +  PA G P SP P            L   PE+ L  + A  P 
Sbjct: 112 E--APALFRPCTPAVWAPAPAAGGPRSPPP------------LLLLPES-LPGSSASVPP 156

Query: 201 LVPAALGSLTTAQIARSVWRPW 222
             PA+     +  +   VWRPW
Sbjct: 157 PQPASSRCAESPGLGLRVWRPW 178


>gi|4503299 basic helix-loop-helix family, member e40 [Homo sapiens]
          Length = 412

 Score = 47.4 bits (111), Expect = 1e-05
 Identities = 48/184 (26%), Positives = 76/184 (41%), Gaps = 32/184 (17%)

Query: 14  REDEDGWETRGDRKARKPLVEKKRRARINESLQELRLLL-----AGAEAKLENAEVLELT 68
           +  ED  ET    K    L+EKKRR RINE + +L+ LL           LE A VLELT
Sbjct: 44  KRSEDSKETY---KLPHRLIEKKRRDRINECIAQLKDLLPEHLKLTTLGHLEKAVVLELT 100

Query: 69  VRRVQGVLRGRAREREQLQAEAS----------------ERFAAGYIQCMHEVHTFVSTC 112
           ++ V+ +     ++++++ A  S                E F +G+  C  EV  +++  
Sbjct: 101 LKHVKALTNLIDQQQQKIIALQSGLQAGELSGRNVETGQEMFCSGFQTCAREVLQYLAKH 160

Query: 113 QAIDATVAAELLNHLLESMPLREGSSFQDLLGDALAGPPRAPGRSGWPAGGAPGSPIPSP 172
           +      +++L+ HL   +         +LL    +  P  P          P SP    
Sbjct: 161 ENTRDLKSSQLVTHLHRVV--------SELLQGGTSRKPSDPAPKVMDFKEKPSSPAKGS 212

Query: 173 PGPG 176
            GPG
Sbjct: 213 EGPG 216


>gi|13540521 basic helix-loop-helix domain containing, class B, 3
           [Homo sapiens]
          Length = 482

 Score = 41.6 bits (96), Expect = 5e-04
 Identities = 42/162 (25%), Positives = 71/162 (43%), Gaps = 34/162 (20%)

Query: 21  ETRGDRKARKPLVEKKRRARINESLQELRLLL-----AGAEAKLENAEVLELTVRRVQGV 75
           +T+   K    L+EKKRR RINE + +L+ LL           LE A VLELT++ ++ +
Sbjct: 40  DTKDTYKLPHRLIEKKRRDRINECIAQLKDLLPEHLKLTTLGHLEKAVVLELTLKHLKAL 99

Query: 76  LRGRAREREQLQA-EASER------------FAAGYIQCMHEVHTFVSTCQAIDATV--A 120
                ++ +++ A +  ER            F +G+  C  EV  ++S  ++        
Sbjct: 100 TALTEQQHQKIIALQNGERSLKSPIQSDLDAFHSGFQTCAKEVLQYLSRFESWTPREPRC 159

Query: 121 AELLNH--------------LLESMPLREGSSFQDLLGDALA 148
            +L+NH              L + +PL +G+      G A A
Sbjct: 160 VQLINHLHAVATQFLPTPQLLTQQVPLSKGTGAPSAAGSAAA 201


>gi|52630419 sterol regulatory element binding transcription factor
           1 isoform a [Homo sapiens]
          Length = 1177

 Score = 40.4 bits (93), Expect = 0.001
 Identities = 41/155 (26%), Positives = 66/155 (42%), Gaps = 16/155 (10%)

Query: 21  ETRGDRKARKPLVEKKRRARINESLQELRLLLAGAEAKLENAEVLELTVRRVQGVLRGRA 80
           ++RG+++     +EK+ R+ IN+ + EL+ L+ G EAKL  + VL    R+    +R   
Sbjct: 349 QSRGEKRTAHNAIEKRYRSSINDKIIELKDLVVGTEAKLNKSAVL----RKAIDYIRFLQ 404

Query: 81  REREQLQAEASERFAAGYIQCMHEVHTFVSTCQAIDAT------VAAELLNHLLESMPLR 134
              ++L+ E      A  +     +   VS C +   T      V  E +   L   P  
Sbjct: 405 HSNQKLKQENLSLRTA--VHKSKSLKDLVSACGSGGNTDVLMEGVKTE-VEDTLTPPPSD 461

Query: 135 EGSSFQDLLGDALAGPPRAPGRSGWPAGGAPGSPI 169
            GS FQ      L+   R  G  G  +   P SP+
Sbjct: 462 AGSPFQ---SSPLSLGSRGSGSGGSGSDSEPDSPV 493


>gi|22547195 sterol regulatory element binding transcription factor
           1 isoform b [Homo sapiens]
          Length = 1147

 Score = 40.4 bits (93), Expect = 0.001
 Identities = 41/155 (26%), Positives = 66/155 (42%), Gaps = 16/155 (10%)

Query: 21  ETRGDRKARKPLVEKKRRARINESLQELRLLLAGAEAKLENAEVLELTVRRVQGVLRGRA 80
           ++RG+++     +EK+ R+ IN+ + EL+ L+ G EAKL  + VL    R+    +R   
Sbjct: 319 QSRGEKRTAHNAIEKRYRSSINDKIIELKDLVVGTEAKLNKSAVL----RKAIDYIRFLQ 374

Query: 81  REREQLQAEASERFAAGYIQCMHEVHTFVSTCQAIDAT------VAAELLNHLLESMPLR 134
              ++L+ E      A  +     +   VS C +   T      V  E +   L   P  
Sbjct: 375 HSNQKLKQENLSLRTA--VHKSKSLKDLVSACGSGGNTDVLMEGVKTE-VEDTLTPPPSD 431

Query: 135 EGSSFQDLLGDALAGPPRAPGRSGWPAGGAPGSPI 169
            GS FQ      L+   R  G  G  +   P SP+
Sbjct: 432 AGSPFQ---SSPLSLGSRGSGSGGSGSDSEPDSPV 463


>gi|110556636 tankyrase 1-binding protein 1 [Homo sapiens]
          Length = 1729

 Score = 37.0 bits (84), Expect = 0.013
 Identities = 25/61 (40%), Positives = 27/61 (44%), Gaps = 3/61 (4%)

Query: 149 GPPRAPGRSGWPAGGAPGSPIPSPPGPGDDLCSDLEEAPEAELSQA---PAEGPDLVPAA 205
           G P +PG     +G  PGSP   PP       S L EA   E SQA   PA  P    AA
Sbjct: 283 GGPASPGLPAEASGSGPGSPHLHPPDKSSPCHSQLLEAQTPEASQASPCPAVTPSAPSAA 342

Query: 206 L 206
           L
Sbjct: 343 L 343


>gi|116008152 alpha 1 type XV collagen precursor [Homo sapiens]
          Length = 1388

 Score = 36.2 bits (82), Expect = 0.023
 Identities = 17/28 (60%), Positives = 17/28 (60%), Gaps = 1/28 (3%)

Query: 149  GPPRAPGRSGWPAGGAPGSP-IPSPPGP 175
            GPP APG  G P  G PG P  P PPGP
Sbjct: 1076 GPPGAPGLPGPPGFGRPGDPGPPGPPGP 1103



 Score = 31.6 bits (70), Expect = 0.56
 Identities = 17/32 (53%), Positives = 19/32 (59%), Gaps = 2/32 (6%)

Query: 147 LAGPPRAPGRSGWP-AGGAPGSP-IPSPPGPG 176
           L GPP   G++G P   G PG P  P PPGPG
Sbjct: 701 LPGPPGKKGQAGPPGVMGPPGPPGPPGPPGPG 732



 Score = 29.6 bits (65), Expect = 2.1
 Identities = 28/79 (35%), Positives = 32/79 (40%), Gaps = 16/79 (20%)

Query: 136 GSSFQDLLGDALA-----GPPRAPGRSGWPAGGAPGSPI-PSPPG-PGDDLCSDLEEAPE 188
           GS   DL+G         GPP  PG  G P  G PG+ +   PPG PG+D        P 
Sbjct: 604 GSGSGDLVGSEQLLRGPPGPPGPPGLPGIP--GKPGTDVFMGPPGSPGED-------GPA 654

Query: 189 AELSQAPAEGPDLVPAALG 207
            E      EG   V  A G
Sbjct: 655 GEPGPPGPEGQPGVDGATG 673


>gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]
          Length = 1838

 Score = 35.8 bits (81), Expect = 0.030
 Identities = 23/65 (35%), Positives = 31/65 (47%), Gaps = 7/65 (10%)

Query: 149  GPPRAPGRSGWPAG-----GAPGSPIPS-PPGPGDDLCSDLEEAPEAELSQAPAEGPDLV 202
            GP  +PG  G PAG     G PG P P  PPGP  +  +  E+ P+    +   +GP  +
Sbjct: 1084 GPAGSPGERG-PAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGL 1142

Query: 203  PAALG 207
            P   G
Sbjct: 1143 PGPAG 1147



 Score = 32.0 bits (71), Expect = 0.43
 Identities = 15/36 (41%), Positives = 19/36 (52%)

Query: 140 QDLLGDALAGPPRAPGRSGWPAGGAPGSPIPSPPGP 175
           QD + + + GP    G+ G PA   PG  I  PPGP
Sbjct: 438 QDTIYEGIGGPRGEKGQKGEPAIIEPGMLIEGPPGP 473



 Score = 29.6 bits (65), Expect = 2.1
 Identities = 23/73 (31%), Positives = 31/73 (42%), Gaps = 4/73 (5%)

Query: 148  AGPPRAPGRSGWPAG--GAPGSP-IPSPPGPGDDLCSDLEEAPEAELSQAPAEGPDLVPA 204
            +GP    G +G P+G  G PG P +P PPGP     S     P+ E       GP   P 
Sbjct: 1512 SGPKGEQGITG-PSGPIGPPGPPGLPGPPGPKGAKGSSGPTGPKGEAGHPGPPGPPGPPG 1570

Query: 205  ALGSLTTAQIARS 217
             +      Q +R+
Sbjct: 1571 EVIQPLPIQASRT 1583


>gi|6912492 mitogen-activated protein kinase 8 interacting protein 2
           isoform 1 [Homo sapiens]
          Length = 824

 Score = 35.8 bits (81), Expect = 0.030
 Identities = 30/81 (37%), Positives = 37/81 (45%), Gaps = 5/81 (6%)

Query: 123 LLNHLLESMPLREGSSFQDLLGDALAGPPRAPGRSGWPAGGA--PGSPIPSPPGPGDDLC 180
           LL++L+  M + EGSS     G  L+  PR PG    PAGGA        +  GPG    
Sbjct: 350 LLSNLVSRM-ISEGSSPIRCPGQCLSPAPRPPGEPVSPAGGAAQDSQDPEAAAGPGGVEL 408

Query: 181 SDLEE--APEAELSQAPAEGP 199
            D+E   AP      AP  GP
Sbjct: 409 VDMETLCAPPPPAPAAPRPGP 429


>gi|7706537 mitogen-activated protein kinase 8 interacting protein 2
           isoform 2 [Homo sapiens]
          Length = 797

 Score = 35.8 bits (81), Expect = 0.030
 Identities = 30/81 (37%), Positives = 37/81 (45%), Gaps = 5/81 (6%)

Query: 123 LLNHLLESMPLREGSSFQDLLGDALAGPPRAPGRSGWPAGGA--PGSPIPSPPGPGDDLC 180
           LL++L+  M + EGSS     G  L+  PR PG    PAGGA        +  GPG    
Sbjct: 323 LLSNLVSRM-ISEGSSPIRCPGQCLSPAPRPPGEPVSPAGGAAQDSQDPEAAAGPGGVEL 381

Query: 181 SDLEE--APEAELSQAPAEGP 199
            D+E   AP      AP  GP
Sbjct: 382 VDMETLCAPPPPAPAAPRPGP 402


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 35.4 bits (80), Expect = 0.039
 Identities = 31/87 (35%), Positives = 36/87 (41%), Gaps = 18/87 (20%)

Query: 144 GDALAGPP-----RAPGRSGWPAG--------GAPGSPIPSPP--GPG--DDLCSDLE-E 185
           G A A PP      A   + W  G        GAPG+P+P PP  GPG  D LC+  E E
Sbjct: 651 GGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETE 710

Query: 186 APEAELSQAPAEGPDLVPAALGSLTTA 212
            PE+      A  P   P   G    A
Sbjct: 711 GPESATPAPGALDPGPSPGTSGGKAAA 737



 Score = 28.5 bits (62), Expect = 4.8
 Identities = 22/57 (38%), Positives = 25/57 (43%), Gaps = 5/57 (8%)

Query: 150 PPRAPGRSGWPAGGAPGSPIPSPPGPGDDLCSDLEEAPEA---ELSQAPAEGPDLVP 203
           PP+AP     P   AP SP  SP  P   L +   +AP A    L QAP   P   P
Sbjct: 393 PPQAPPALALPPLQAPPSPPASP--PLSPLATPSPQAPNALAVHLLQAPFSPPPSPP 447


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
          Length = 1124

 Score = 35.4 bits (80), Expect = 0.039
 Identities = 31/87 (35%), Positives = 36/87 (41%), Gaps = 18/87 (20%)

Query: 144  GDALAGPP-----RAPGRSGWPAG--------GAPGSPIPSPP--GPG--DDLCSDLE-E 185
            G A A PP      A   + W  G        GAPG+P+P PP  GPG  D LC+  E E
Sbjct: 920  GGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETE 979

Query: 186  APEAELSQAPAEGPDLVPAALGSLTTA 212
             PE+      A  P   P   G    A
Sbjct: 980  GPESATPAPGALDPGPSPGTSGGKAAA 1006



 Score = 28.5 bits (62), Expect = 4.8
 Identities = 22/57 (38%), Positives = 25/57 (43%), Gaps = 5/57 (8%)

Query: 150 PPRAPGRSGWPAGGAPGSPIPSPPGPGDDLCSDLEEAPEA---ELSQAPAEGPDLVP 203
           PP+AP     P   AP SP  SP  P   L +   +AP A    L QAP   P   P
Sbjct: 618 PPQAPPXLALPPLQAPPSPPASP--PLSPLATPSPQAPNALAVHLLQAPFSPPPSPP 672


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 35.4 bits (80), Expect = 0.039
 Identities = 31/87 (35%), Positives = 36/87 (41%), Gaps = 18/87 (20%)

Query: 144 GDALAGPP-----RAPGRSGWPAG--------GAPGSPIPSPP--GPG--DDLCSDLE-E 185
           G A A PP      A   + W  G        GAPG+P+P PP  GPG  D LC+  E E
Sbjct: 612 GGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETE 671

Query: 186 APEAELSQAPAEGPDLVPAALGSLTTA 212
            PE+      A  P   P   G    A
Sbjct: 672 GPESATPAPGALDPGPSPGTSGGKAAA 698



 Score = 28.5 bits (62), Expect = 4.8
 Identities = 22/57 (38%), Positives = 25/57 (43%), Gaps = 5/57 (8%)

Query: 150 PPRAPGRSGWPAGGAPGSPIPSPPGPGDDLCSDLEEAPEA---ELSQAPAEGPDLVP 203
           PP+AP     P   AP SP  SP  P   L +   +AP A    L QAP   P   P
Sbjct: 354 PPQAPPALALPPLQAPPSPPASP--PLSPLATPSPQAPNALAVHLLQAPFSPPPSPP 408


>gi|154355000 KH-type splicing regulatory protein [Homo sapiens]
          Length = 711

 Score = 35.4 bits (80), Expect = 0.039
 Identities = 17/29 (58%), Positives = 17/29 (58%), Gaps = 1/29 (3%)

Query: 149 GPPRAPGRSGWPAGGAPGSPIPSPPGPGD 177
           GPP  P   G  AGGA G P P PPG GD
Sbjct: 12  GPP-PPAGGGGGAGGAGGGPPPGPPGAGD 39



 Score = 28.1 bits (61), Expect = 6.2
 Identities = 16/37 (43%), Positives = 17/37 (45%), Gaps = 3/37 (8%)

Query: 141 DLLGDALAGPPRAPGRSGWPAGG---APGSPIPSPPG 174
           DLL    +GPP  PG  G P GG     G     PPG
Sbjct: 388 DLLQSLRSGPPGPPGGPGMPPGGRGRGRGQGNWGPPG 424


>gi|27477113 sterol regulatory element-binding transcription factor
           2 [Homo sapiens]
          Length = 1141

 Score = 35.4 bits (80), Expect = 0.039
 Identities = 15/46 (32%), Positives = 29/46 (63%)

Query: 24  GDRKARKPLVEKKRRARINESLQELRLLLAGAEAKLENAEVLELTV 69
           G+R+    ++EK+ R+ IN+ + EL+ L+ G +AK+  + VL   +
Sbjct: 329 GERRTTHNIIEKRYRSSINDKIIELKDLVMGTDAKMHKSGVLRKAI 374


>gi|110556644 zinc finger protein, multitype 1 [Homo sapiens]
          Length = 1006

 Score = 35.4 bits (80), Expect = 0.039
 Identities = 31/81 (38%), Positives = 35/81 (43%), Gaps = 9/81 (11%)

Query: 127 LLESMPLREGSSFQDLLGDALAGP---PRAPGRSG-WPAGGAPGSPIPSPPGPGDDLCSD 182
           LLE   L  G     LLG  LAGP    R P   G  PA     SP P   GP D L  +
Sbjct: 869 LLEHFRLAHGL----LLGAPLAGPGVEARTPADRGPSPAPAPAASPQPGSRGPRDGLGPE 924

Query: 183 LEEAPEAELSQAPAEGPDLVP 203
            +E P      +PA  P+ VP
Sbjct: 925 PQEPPPGP-PPSPAAAPEAVP 944



 Score = 31.2 bits (69), Expect = 0.74
 Identities = 21/57 (36%), Positives = 23/57 (40%), Gaps = 8/57 (14%)

Query: 148 AGPPRAPG--------RSGWPAGGAPGSPIPSPPGPGDDLCSDLEEAPEAELSQAPA 196
           A PP  PG        R G  +G  PG      PGP  D   DL + P   L  APA
Sbjct: 754 APPPPPPGHAPAPESPRPGSGSGSGPGLAPARSPGPAADGPIDLSKKPRRPLPGAPA 810


>gi|169207312 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 414

 Score = 35.0 bits (79), Expect = 0.051
 Identities = 20/60 (33%), Positives = 29/60 (48%), Gaps = 6/60 (10%)

Query: 151 PRAPGRSGWPAGGAPGSPIPSP----PGPGDDLCSDLEEAPEAELS--QAPAEGPDLVPA 204
           P  P  + WPA GAPG+P P+     PGP     S  +E     ++  +   EG +L P+
Sbjct: 322 PAPPAPTAWPAAGAPGAPNPAESRRGPGPAQGPPSRRDEPRRVVIAARECGREGSELPPS 381


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.132    0.395 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,383,149
Number of Sequences: 37866
Number of extensions: 618293
Number of successful extensions: 5742
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 119
Number of HSP's successfully gapped in prelim test: 396
Number of HSP's that attempted gapping in prelim test: 4476
Number of HSP's gapped (non-prelim): 1643
length of query: 222
length of database: 18,247,518
effective HSP length: 98
effective length of query: 124
effective length of database: 14,536,650
effective search space: 1802544600
effective search space used: 1802544600
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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