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Search of human proteins with 218751874
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|218751874 hairy and enhancer of split 6 isoform b [Homo
sapiens]
(222 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|218751874 hairy and enhancer of split 6 isoform b [Homo sapiens] 447 e-126
gi|21361763 hairy and enhancer of split 6 isoform a [Homo sapiens] 442 e-124
gi|5031763 hairy and enhancer of split 1 [Homo sapiens] 99 3e-21
gi|216548627 hairy and enhancer of split 4 isoform 1 [Homo sapiens] 89 3e-18
gi|10863967 hairy and enhancer of split 4 isoform 2 [Homo sapiens] 89 3e-18
gi|63055047 hairy and enhancer of split homolog 2 [Homo sapiens] 77 2e-14
gi|105990528 hairy/enhancer-of-split related with YRPW motif 1 i... 65 6e-11
gi|105990526 hairy/enhancer-of-split related with YRPW motif 1 i... 63 2e-10
gi|6912414 hairy/enhancer-of-split related with YRPW motif 2 [Ho... 63 2e-10
gi|145207994 hairy and enhancer of split 7 [Homo sapiens] 56 2e-08
gi|7657154 hairy/enhancer-of-split related with YRPW motif-like ... 52 5e-07
gi|58219048 hairy and enhancer of split 5 [Homo sapiens] 52 5e-07
gi|71274142 HES/HEY-like transcription factor [Homo sapiens] 52 5e-07
gi|66912172 hairy and enhancer of split 3 [Homo sapiens] 48 8e-06
gi|4503299 basic helix-loop-helix family, member e40 [Homo sapiens] 47 1e-05
gi|13540521 basic helix-loop-helix domain containing, class B, 3... 42 5e-04
gi|52630419 sterol regulatory element binding transcription fact... 40 0.001
gi|22547195 sterol regulatory element binding transcription fact... 40 0.001
gi|110556636 tankyrase 1-binding protein 1 [Homo sapiens] 37 0.013
gi|116008152 alpha 1 type XV collagen precursor [Homo sapiens] 36 0.023
gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens] 36 0.030
gi|6912492 mitogen-activated protein kinase 8 interacting protei... 36 0.030
gi|7706537 mitogen-activated protein kinase 8 interacting protei... 36 0.030
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 35 0.039
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 35 0.039
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 35 0.039
gi|154355000 KH-type splicing regulatory protein [Homo sapiens] 35 0.039
gi|27477113 sterol regulatory element-binding transcription fact... 35 0.039
gi|110556644 zinc finger protein, multitype 1 [Homo sapiens] 35 0.039
gi|169207312 PREDICTED: hypothetical protein [Homo sapiens] 35 0.051
>gi|218751874 hairy and enhancer of split 6 isoform b [Homo sapiens]
Length = 222
Score = 447 bits (1149), Expect = e-126
Identities = 222/222 (100%), Positives = 222/222 (100%)
Query: 1 MAPPAAPGRDRVGREDEDGWETRGDRKARKPLVEKKRRARINESLQELRLLLAGAEAKLE 60
MAPPAAPGRDRVGREDEDGWETRGDRKARKPLVEKKRRARINESLQELRLLLAGAEAKLE
Sbjct: 1 MAPPAAPGRDRVGREDEDGWETRGDRKARKPLVEKKRRARINESLQELRLLLAGAEAKLE 60
Query: 61 NAEVLELTVRRVQGVLRGRAREREQLQAEASERFAAGYIQCMHEVHTFVSTCQAIDATVA 120
NAEVLELTVRRVQGVLRGRAREREQLQAEASERFAAGYIQCMHEVHTFVSTCQAIDATVA
Sbjct: 61 NAEVLELTVRRVQGVLRGRAREREQLQAEASERFAAGYIQCMHEVHTFVSTCQAIDATVA 120
Query: 121 AELLNHLLESMPLREGSSFQDLLGDALAGPPRAPGRSGWPAGGAPGSPIPSPPGPGDDLC 180
AELLNHLLESMPLREGSSFQDLLGDALAGPPRAPGRSGWPAGGAPGSPIPSPPGPGDDLC
Sbjct: 121 AELLNHLLESMPLREGSSFQDLLGDALAGPPRAPGRSGWPAGGAPGSPIPSPPGPGDDLC 180
Query: 181 SDLEEAPEAELSQAPAEGPDLVPAALGSLTTAQIARSVWRPW 222
SDLEEAPEAELSQAPAEGPDLVPAALGSLTTAQIARSVWRPW
Sbjct: 181 SDLEEAPEAELSQAPAEGPDLVPAALGSLTTAQIARSVWRPW 222
>gi|21361763 hairy and enhancer of split 6 isoform a [Homo sapiens]
Length = 224
Score = 442 bits (1136), Expect = e-124
Identities = 222/224 (99%), Positives = 222/224 (99%), Gaps = 2/224 (0%)
Query: 1 MAPPAAPGRDRVGREDEDGWETRGDRKARKPLVEKKRRARINESLQELRLLLAGAE--AK 58
MAPPAAPGRDRVGREDEDGWETRGDRKARKPLVEKKRRARINESLQELRLLLAGAE AK
Sbjct: 1 MAPPAAPGRDRVGREDEDGWETRGDRKARKPLVEKKRRARINESLQELRLLLAGAEVQAK 60
Query: 59 LENAEVLELTVRRVQGVLRGRAREREQLQAEASERFAAGYIQCMHEVHTFVSTCQAIDAT 118
LENAEVLELTVRRVQGVLRGRAREREQLQAEASERFAAGYIQCMHEVHTFVSTCQAIDAT
Sbjct: 61 LENAEVLELTVRRVQGVLRGRAREREQLQAEASERFAAGYIQCMHEVHTFVSTCQAIDAT 120
Query: 119 VAAELLNHLLESMPLREGSSFQDLLGDALAGPPRAPGRSGWPAGGAPGSPIPSPPGPGDD 178
VAAELLNHLLESMPLREGSSFQDLLGDALAGPPRAPGRSGWPAGGAPGSPIPSPPGPGDD
Sbjct: 121 VAAELLNHLLESMPLREGSSFQDLLGDALAGPPRAPGRSGWPAGGAPGSPIPSPPGPGDD 180
Query: 179 LCSDLEEAPEAELSQAPAEGPDLVPAALGSLTTAQIARSVWRPW 222
LCSDLEEAPEAELSQAPAEGPDLVPAALGSLTTAQIARSVWRPW
Sbjct: 181 LCSDLEEAPEAELSQAPAEGPDLVPAALGSLTTAQIARSVWRPW 224
>gi|5031763 hairy and enhancer of split 1 [Homo sapiens]
Length = 280
Score = 99.0 bits (245), Expect = 3e-21
Identities = 75/247 (30%), Positives = 110/247 (44%), Gaps = 53/247 (21%)
Query: 26 RKARKPLVEKKRRARINESLQELRLLLAGA-------EAKLENAEVLELTVRRVQGVLRG 78
RK+ KP++EK+RRARINESL +L+ L+ A +KLE A++LE+TV+ ++ + R
Sbjct: 35 RKSSKPIMEKRRRARINESLSQLKTLILDALKKDSSRHSKLEKADILEMTVKHLRNLQRA 94
Query: 79 RAREREQLQAEASERFAAGYIQCMHEVHTFVSTCQAIDATVAAELLNHLLESMPLREGSS 138
+ ++ AG+ +CM+EV F+STC+ ++ V LL HL M +
Sbjct: 95 QMTAALSTDPSVLGKYRAGFSECMNEVTRFLSTCEGVNTEVRTRLLGHLANCMTQINAMT 154
Query: 139 FQDLLGDALAGPPRAPGRSGWP-----AGGAPGSPIP--SPPGPGDDLCSDLEEAPEA-- 189
+ AL PP P G P A P PIP + P PG C +A EA
Sbjct: 155 YPGQPHPALQAPPPPPPGPGGPQHAPFAPPPPLVPIPGGAAPPPGGAPCKLGSQAGEAAK 214
Query: 190 -----ELSQAP-----------------------------AEGPDLVPAALGSLTTAQIA 215
++ AP + GP+ V + G TA
Sbjct: 215 VFGGFQVVPAPDGQFAFLIPNGAFAHSGPVIPVYTSNSGTSVGPNAVSPSSGPSLTAD-- 272
Query: 216 RSVWRPW 222
S+WRPW
Sbjct: 273 -SMWRPW 278
>gi|216548627 hairy and enhancer of split 4 isoform 1 [Homo sapiens]
Length = 247
Score = 89.0 bits (219), Expect = 3e-18
Identities = 69/228 (30%), Positives = 102/228 (44%), Gaps = 35/228 (15%)
Query: 7 PG-RDRVGREDEDGWETRGDRKARKPLVEKKRRARINESLQELRLLLAGA-------EAK 58
PG R G + G + D ++ KP++EK+RRARINESL +L+ L+ A +K
Sbjct: 41 PGVRGATGGREGRGTQPVPDPQSSKPVMEKRRRARINESLAQLKTLILDALRKESSRHSK 100
Query: 59 LENAEVLELTVRRVQGVLRGRAREREQLQAEASERFAAGYIQCMHEVHTFVSTCQAIDAT 118
LE A++LE+TVR ++ + R + ++ AG+ +C+ EV+ F++ C+ + A
Sbjct: 101 LEKADILEMTVRHLRSLRRVQVTAALSADPAVLGKYRAGFHECLAEVNRFLAGCEGVPAD 160
Query: 119 VAAELLNHLLESM----PLREGSSFQDLLGDALAGPPRAPGRSGWPAGGAPGSPIPSPPG 174
V + LL HL + P R +S P AP + P A +PS G
Sbjct: 161 VRSRLLGHLAACLRQLGPSRRPASLS----------PAAPAEAPAPEVYAGRPLLPSLGG 210
Query: 175 PGDDLCSDLEEAPEAELSQAPAEGPDLVPAALGSLTTAQIARSVWRPW 222
P L L L AP GP Q WRPW
Sbjct: 211 PFPLLAPPLLPGLTRALPAAPRAGP-------------QGPGGPWRPW 245
>gi|10863967 hairy and enhancer of split 4 isoform 2 [Homo sapiens]
Length = 221
Score = 89.0 bits (219), Expect = 3e-18
Identities = 69/232 (29%), Positives = 100/232 (43%), Gaps = 34/232 (14%)
Query: 2 APPAAPGRDRVGREDEDGWETRGDRKARKPLVEKKRRARINESLQELRLLLAGA------ 55
A P A R + RK+ KP++EK+RRARINESL +L+ L+ A
Sbjct: 11 ASPMAGAPASASRTPDKPRSAAEHRKSSKPVMEKRRRARINESLAQLKTLILDALRKESS 70
Query: 56 -EAKLENAEVLELTVRRVQGVLRGRAREREQLQAEASERFAAGYIQCMHEVHTFVSTCQA 114
+KLE A++LE+TVR ++ + R + ++ AG+ +C+ EV+ F++ C+
Sbjct: 71 RHSKLEKADILEMTVRHLRSLRRVQVTAALSADPAVLGKYRAGFHECLAEVNRFLAGCEG 130
Query: 115 IDATVAAELLNHLLESM----PLREGSSFQDLLGDALAGPPRAPGRSGWPAGGAPGSPIP 170
+ A V + LL HL + P R +S P AP + P A +P
Sbjct: 131 VPADVRSRLLGHLAACLRQLGPSRRPASLS----------PAAPAEAPAPEVYAGRPLLP 180
Query: 171 SPPGPGDDLCSDLEEAPEAELSQAPAEGPDLVPAALGSLTTAQIARSVWRPW 222
S GP L L L AP GP Q WRPW
Sbjct: 181 SLGGPFPLLAPPLLPGLTRALPAAPRAGP-------------QGPGGPWRPW 219
>gi|63055047 hairy and enhancer of split homolog 2 [Homo sapiens]
Length = 173
Score = 76.6 bits (187), Expect = 2e-14
Identities = 56/159 (35%), Positives = 83/159 (52%), Gaps = 18/159 (11%)
Query: 26 RKARKPLVEKKRRARINESLQELR---LLLAGAE----AKLENAEVLELTVRRVQGVLRG 78
RK+ KPL+EK+RRARIN+SL +L+ L L G E +KLE A+VLE+TVR +Q +
Sbjct: 14 RKSLKPLLEKRRRARINQSLSQLKGLILPLLGRENSNCSKLEKADVLEMTVRFLQELPAS 73
Query: 79 RAREREQLQAEASERFAAGYIQCMHEVHTFVSTCQAIDATVAAELLNHLLE--SMPLREG 136
L ++ + GY C+ + + C+ ++ V+A LL HL + +G
Sbjct: 74 SWPTAAPLPCDS---YREGYSACVARLARVLPACRVLEPAVSARLLEHLWRRAASATLDG 130
Query: 137 SSFQDLLGDALAGPPRAPGRSGWPAGGAPGSPIPSPPGP 175
D G + P AP + PA +P+PSPP P
Sbjct: 131 GRAGDSSGPSAPAP--APASAPEPA----SAPVPSPPSP 163
>gi|105990528 hairy/enhancer-of-split related with YRPW motif 1
isoform a [Homo sapiens]
Length = 304
Score = 64.7 bits (156), Expect = 6e-11
Identities = 58/194 (29%), Positives = 88/194 (45%), Gaps = 16/194 (8%)
Query: 26 RKARKPLVEKKRRARINESLQELRLLLAGA-----EAKLENAEVLELTVRRVQGVLRGRA 80
RK R+ ++EK+RR RIN SL ELR L+ A AKLE AE+L++TV ++ +
Sbjct: 50 RKRRRGIIEKRRRDRINNSLSELRRLVPSAFEKQGSAKLEKAEILQMTVDHLKMLHTAGG 109
Query: 81 REREQLQAEASERFAAGYIQCMHEVHTFVSTCQAIDAT--VAAELLNHLLESMPLREGSS 138
+ A A + + G+ +C+ EV ++S + +DA+ + L++HL RE +S
Sbjct: 110 KGYFDAHALAMDYRSLGFRECLAEVARYLSIIEGLDASDPLRVRLVSHLNNYASQREAAS 169
Query: 139 FQDLLGDALAGPPRAPGRSGWPAGGAPGSPIPSPP---GPGDDLCSDLEEAPEAELSQAP 195
A AG P + + P+ P G S E + L A
Sbjct: 170 ------GAHAGLGHIPWGTVFGHHPHIAHPLLLPQNGHGNAGTTASPTEPHHQGRLGSAH 223
Query: 196 AEGPDLVPAALGSL 209
E P L GSL
Sbjct: 224 PEAPALRAPPSGSL 237
>gi|105990526 hairy/enhancer-of-split related with YRPW motif 1
isoform b [Homo sapiens]
Length = 308
Score = 63.2 bits (152), Expect = 2e-10
Identities = 58/198 (29%), Positives = 88/198 (44%), Gaps = 20/198 (10%)
Query: 26 RKARKPLVEKKRRARINESLQELRLLLAGA---------EAKLENAEVLELTVRRVQGVL 76
RK R+ ++EK+RR RIN SL ELR L+ A AKLE AE+L++TV ++ +
Sbjct: 50 RKRRRGIIEKRRRDRINNSLSELRRLVPSAFEKQVMEQGSAKLEKAEILQMTVDHLKMLH 109
Query: 77 RGRAREREQLQAEASERFAAGYIQCMHEVHTFVSTCQAIDAT--VAAELLNHLLESMPLR 134
+ A A + + G+ +C+ EV ++S + +DA+ + L++HL R
Sbjct: 110 TAGGKGYFDAHALAMDYRSLGFRECLAEVARYLSIIEGLDASDPLRVRLVSHLNNYASQR 169
Query: 135 EGSSFQDLLGDALAGPPRAPGRSGWPAGGAPGSPIPSPP---GPGDDLCSDLEEAPEAEL 191
E +S A AG P + + P+ P G S E + L
Sbjct: 170 EAAS------GAHAGLGHIPWGTVFGHHPHIAHPLLLPQNGHGNAGTTASPTEPHHQGRL 223
Query: 192 SQAPAEGPDLVPAALGSL 209
A E P L GSL
Sbjct: 224 GSAHPEAPALRAPPSGSL 241
>gi|6912414 hairy/enhancer-of-split related with YRPW motif 2 [Homo
sapiens]
Length = 337
Score = 62.8 bits (151), Expect = 2e-10
Identities = 39/120 (32%), Positives = 68/120 (56%), Gaps = 7/120 (5%)
Query: 26 RKARKPLVEKKRRARINESLQELRLLLAGA-----EAKLENAEVLELTVRRVQGVLRGRA 80
RK R+ ++EK+RR RIN SL ELR L+ A AKLE AE+L++TV ++ +
Sbjct: 49 RKKRRGIIEKRRRDRINNSLSELRRLVPTAFEKQGSAKLEKAEILQMTVDHLKMLQATGG 108
Query: 81 REREQLQAEASERFAAGYIQCMHEVHTFVSTCQAIDAT--VAAELLNHLLESMPLREGSS 138
+ A A + + G+ +C+ EV ++S+ + +D++ + L++HL RE ++
Sbjct: 109 KGYFDAHALAMDFMSIGFRECLTEVARYLSSVEGLDSSDPLRVRLVSHLSTCATQREAAA 168
>gi|145207994 hairy and enhancer of split 7 [Homo sapiens]
Length = 225
Score = 56.2 bits (134), Expect = 2e-08
Identities = 75/250 (30%), Positives = 92/250 (36%), Gaps = 75/250 (30%)
Query: 18 DGWETRGDRKARKPLVEKKRRARINESLQELRLLLAG-------AEAKLENAEVLELTVR 70
D E R K KPLVEK+RR RIN SL+ELRLLL KLE AE+LE V
Sbjct: 5 DRAENRDGPKMLKPLVEKRRRDRINRSLEELRLLLLERTRDQNLRNPKLEKAEILEFAV- 63
Query: 71 RVQGVLRGRAR------EREQLQ-AEA-SERFAAGYIQCMHEVHTFVSTCQAIDATVAAE 122
G LR R+R R +Q AEA + + +G+ +C+ + F
Sbjct: 64 ---GYLRERSRVEPPGVPRSPVQDAEALASCYLSGFRECLLRLAAFAHDASPAARAQLFS 120
Query: 123 LLNHLLESMPLREG-------------SSFQDLLGDAL-AGPPRAPG----RSGW----- 159
L+ L P R LG AL PP G R W
Sbjct: 121 ALHGYLRPKPPRPKPVDPRPPAPRPSLDPAAPALGPALHQRPPVHQGHPSPRCAWSPSLC 180
Query: 160 -PAGGAPGSP------IPSPPGPGDDLCSDLEEAPEAELSQAPAEGPDLVPAALGSLTTA 212
P G G+P +P PP P + AP+A L PA
Sbjct: 181 SPRAGDSGAPAPLTGLLPPPPPPHRQ-----DGAPKAPLPPPPA---------------- 219
Query: 213 QIARSVWRPW 222
WRPW
Sbjct: 220 -----FWRPW 224
>gi|7657154 hairy/enhancer-of-split related with YRPW motif-like
[Homo sapiens]
Length = 328
Score = 51.6 bits (122), Expect = 5e-07
Identities = 37/110 (33%), Positives = 59/110 (53%), Gaps = 8/110 (7%)
Query: 26 RKARKPLVEKKRRARINESLQELRLLLAGA-----EAKLENAEVLELTVRRVQGVLRGRA 80
RK R+ ++EK+RR RIN SL ELR L+ A +KLE AEVL++TV ++ +
Sbjct: 44 RKKRRGIIEKRRRDRINSSLSELRRLVPTAFEKQGSSKLEKAEVLQMTVDHLKMLHATGG 103
Query: 81 REREQLQAEASERFAAGYIQCMHEVHTFVSTCQAIDA---TVAAELLNHL 127
+A A + + G+ +C+ EV ++ + + V LL+HL
Sbjct: 104 TGFFDARALAVDFRSIGFRECLTEVIRYLGVLEGPSSRADPVRIRLLSHL 153
>gi|58219048 hairy and enhancer of split 5 [Homo sapiens]
Length = 166
Score = 51.6 bits (122), Expect = 5e-07
Identities = 55/202 (27%), Positives = 79/202 (39%), Gaps = 59/202 (29%)
Query: 27 KARKPLVEKKRRARINESLQELRLLLA------GAEAKLENAEVLELTVRRVQGVLRGRA 80
+ RKP+VEK RR RIN S+++L+LLL +KLE A++LE+ V ++ +A
Sbjct: 18 RLRKPVVEKMRRDRINSSIEQLKLLLEQEFARHQPNSKLEKADILEMAVSYLK---HSKA 74
Query: 81 REREQLQAEASERFAAGYIQCMHEVHTFVSTCQAIDATVAAELLNHLLESMPLREGSSFQ 140
+ ++ GY C+ E F++ A D + +LL H FQ
Sbjct: 75 FVAAAGPKSLHQDYSEGYSWCLQEAVQFLTLHAASDTQM--KLLYH------------FQ 120
Query: 141 DLLGDALAGPPRAPGRSGWPAGGAPGSPIPSPPGPGDDLCSDLEEAPEAELSQAPAEGPD 200
PP AP +P P PG AP LS
Sbjct: 121 --------RPP-----------AAPAAPAKEPKAPG--------AAPPPALS-------- 145
Query: 201 LVPAALGSLTTAQIARSVWRPW 222
A + Q A +WRPW
Sbjct: 146 -AKATAAAAAAHQPACGLWRPW 166
>gi|71274142 HES/HEY-like transcription factor [Homo sapiens]
Length = 327
Score = 51.6 bits (122), Expect = 5e-07
Identities = 49/173 (28%), Positives = 73/173 (42%), Gaps = 22/173 (12%)
Query: 51 LLAGAEAKLENAEVLELTVRRVQGVLRG---RAREREQLQAEASERFAAGYIQCMHEVHT 107
LL + KLE AE+LE+TV+ ++ + R RE+ +L AE + F GY +CM +
Sbjct: 126 LLLQSSGKLEKAEILEMTVQYLRALHSADFPRGREKAELLAEFANYFHYGYHECMKNLVH 185
Query: 108 FVSTCQAID----------------ATVAAELLNHLLESMPLREGSSFQDLLGDALAGPP 151
+++T + ++ A + AE L S+P + S G AG
Sbjct: 186 YLTTVERMETKDTKYARILAFLQSKARLGAEPAFPPLGSLPEPDFSYQLHPAGPEFAG-- 243
Query: 152 RAPGRSGWPAGGAPGSPIPSPPGPG-DDLCSDLEEAPEAELSQAPAEGPDLVP 203
+PG + G+ P P PPG L AP S A P L P
Sbjct: 244 HSPGEAAVFPQGSGAGPFPWPPGAARSPALPYLPSAPVPLASPAQQHSPFLTP 296
>gi|66912172 hairy and enhancer of split 3 [Homo sapiens]
Length = 186
Score = 47.8 bits (112), Expect = 8e-06
Identities = 57/202 (28%), Positives = 83/202 (41%), Gaps = 36/202 (17%)
Query: 33 VEKKRRARINESLQELRLLLAG------AEAKLENAEVLELTV---RRVQGVLRGR---A 80
+EKKRRARIN SL++L+ LL + KLE A++LEL+V R +Q L+G
Sbjct: 1 MEKKRRARINVSLEQLKSLLEKHYSHQIRKRKLEKADILELSVKYMRSLQNSLQGLWPVP 60
Query: 81 REREQLQAEASERFAAGYIQCMHEVHTFVSTCQAIDATVAAELLNHLLESMPLREGSSFQ 140
R EQ +G+ C+ V + + + + L+ + Q
Sbjct: 61 RGAEQ---------PSGFRSCLPGVSQLLRRGDEVGSGLRCPLVPESAAGSTMDSAGLGQ 111
Query: 141 DLLGDALAGPPRAPGRSGWPAGGAPGSPIPSPPGPGDDLCSDLEEAPEAELSQAPAEGPD 200
+ AL P + PA G P SP P L PE+ L + A P
Sbjct: 112 E--APALFRPCTPAVWAPAPAAGGPRSPPP------------LLLLPES-LPGSSASVPP 156
Query: 201 LVPAALGSLTTAQIARSVWRPW 222
PA+ + + VWRPW
Sbjct: 157 PQPASSRCAESPGLGLRVWRPW 178
>gi|4503299 basic helix-loop-helix family, member e40 [Homo sapiens]
Length = 412
Score = 47.4 bits (111), Expect = 1e-05
Identities = 48/184 (26%), Positives = 76/184 (41%), Gaps = 32/184 (17%)
Query: 14 REDEDGWETRGDRKARKPLVEKKRRARINESLQELRLLL-----AGAEAKLENAEVLELT 68
+ ED ET K L+EKKRR RINE + +L+ LL LE A VLELT
Sbjct: 44 KRSEDSKETY---KLPHRLIEKKRRDRINECIAQLKDLLPEHLKLTTLGHLEKAVVLELT 100
Query: 69 VRRVQGVLRGRAREREQLQAEAS----------------ERFAAGYIQCMHEVHTFVSTC 112
++ V+ + ++++++ A S E F +G+ C EV +++
Sbjct: 101 LKHVKALTNLIDQQQQKIIALQSGLQAGELSGRNVETGQEMFCSGFQTCAREVLQYLAKH 160
Query: 113 QAIDATVAAELLNHLLESMPLREGSSFQDLLGDALAGPPRAPGRSGWPAGGAPGSPIPSP 172
+ +++L+ HL + +LL + P P P SP
Sbjct: 161 ENTRDLKSSQLVTHLHRVV--------SELLQGGTSRKPSDPAPKVMDFKEKPSSPAKGS 212
Query: 173 PGPG 176
GPG
Sbjct: 213 EGPG 216
>gi|13540521 basic helix-loop-helix domain containing, class B, 3
[Homo sapiens]
Length = 482
Score = 41.6 bits (96), Expect = 5e-04
Identities = 42/162 (25%), Positives = 71/162 (43%), Gaps = 34/162 (20%)
Query: 21 ETRGDRKARKPLVEKKRRARINESLQELRLLL-----AGAEAKLENAEVLELTVRRVQGV 75
+T+ K L+EKKRR RINE + +L+ LL LE A VLELT++ ++ +
Sbjct: 40 DTKDTYKLPHRLIEKKRRDRINECIAQLKDLLPEHLKLTTLGHLEKAVVLELTLKHLKAL 99
Query: 76 LRGRAREREQLQA-EASER------------FAAGYIQCMHEVHTFVSTCQAIDATV--A 120
++ +++ A + ER F +G+ C EV ++S ++
Sbjct: 100 TALTEQQHQKIIALQNGERSLKSPIQSDLDAFHSGFQTCAKEVLQYLSRFESWTPREPRC 159
Query: 121 AELLNH--------------LLESMPLREGSSFQDLLGDALA 148
+L+NH L + +PL +G+ G A A
Sbjct: 160 VQLINHLHAVATQFLPTPQLLTQQVPLSKGTGAPSAAGSAAA 201
>gi|52630419 sterol regulatory element binding transcription factor
1 isoform a [Homo sapiens]
Length = 1177
Score = 40.4 bits (93), Expect = 0.001
Identities = 41/155 (26%), Positives = 66/155 (42%), Gaps = 16/155 (10%)
Query: 21 ETRGDRKARKPLVEKKRRARINESLQELRLLLAGAEAKLENAEVLELTVRRVQGVLRGRA 80
++RG+++ +EK+ R+ IN+ + EL+ L+ G EAKL + VL R+ +R
Sbjct: 349 QSRGEKRTAHNAIEKRYRSSINDKIIELKDLVVGTEAKLNKSAVL----RKAIDYIRFLQ 404
Query: 81 REREQLQAEASERFAAGYIQCMHEVHTFVSTCQAIDAT------VAAELLNHLLESMPLR 134
++L+ E A + + VS C + T V E + L P
Sbjct: 405 HSNQKLKQENLSLRTA--VHKSKSLKDLVSACGSGGNTDVLMEGVKTE-VEDTLTPPPSD 461
Query: 135 EGSSFQDLLGDALAGPPRAPGRSGWPAGGAPGSPI 169
GS FQ L+ R G G + P SP+
Sbjct: 462 AGSPFQ---SSPLSLGSRGSGSGGSGSDSEPDSPV 493
>gi|22547195 sterol regulatory element binding transcription factor
1 isoform b [Homo sapiens]
Length = 1147
Score = 40.4 bits (93), Expect = 0.001
Identities = 41/155 (26%), Positives = 66/155 (42%), Gaps = 16/155 (10%)
Query: 21 ETRGDRKARKPLVEKKRRARINESLQELRLLLAGAEAKLENAEVLELTVRRVQGVLRGRA 80
++RG+++ +EK+ R+ IN+ + EL+ L+ G EAKL + VL R+ +R
Sbjct: 319 QSRGEKRTAHNAIEKRYRSSINDKIIELKDLVVGTEAKLNKSAVL----RKAIDYIRFLQ 374
Query: 81 REREQLQAEASERFAAGYIQCMHEVHTFVSTCQAIDAT------VAAELLNHLLESMPLR 134
++L+ E A + + VS C + T V E + L P
Sbjct: 375 HSNQKLKQENLSLRTA--VHKSKSLKDLVSACGSGGNTDVLMEGVKTE-VEDTLTPPPSD 431
Query: 135 EGSSFQDLLGDALAGPPRAPGRSGWPAGGAPGSPI 169
GS FQ L+ R G G + P SP+
Sbjct: 432 AGSPFQ---SSPLSLGSRGSGSGGSGSDSEPDSPV 463
>gi|110556636 tankyrase 1-binding protein 1 [Homo sapiens]
Length = 1729
Score = 37.0 bits (84), Expect = 0.013
Identities = 25/61 (40%), Positives = 27/61 (44%), Gaps = 3/61 (4%)
Query: 149 GPPRAPGRSGWPAGGAPGSPIPSPPGPGDDLCSDLEEAPEAELSQA---PAEGPDLVPAA 205
G P +PG +G PGSP PP S L EA E SQA PA P AA
Sbjct: 283 GGPASPGLPAEASGSGPGSPHLHPPDKSSPCHSQLLEAQTPEASQASPCPAVTPSAPSAA 342
Query: 206 L 206
L
Sbjct: 343 L 343
>gi|116008152 alpha 1 type XV collagen precursor [Homo sapiens]
Length = 1388
Score = 36.2 bits (82), Expect = 0.023
Identities = 17/28 (60%), Positives = 17/28 (60%), Gaps = 1/28 (3%)
Query: 149 GPPRAPGRSGWPAGGAPGSP-IPSPPGP 175
GPP APG G P G PG P P PPGP
Sbjct: 1076 GPPGAPGLPGPPGFGRPGDPGPPGPPGP 1103
Score = 31.6 bits (70), Expect = 0.56
Identities = 17/32 (53%), Positives = 19/32 (59%), Gaps = 2/32 (6%)
Query: 147 LAGPPRAPGRSGWP-AGGAPGSP-IPSPPGPG 176
L GPP G++G P G PG P P PPGPG
Sbjct: 701 LPGPPGKKGQAGPPGVMGPPGPPGPPGPPGPG 732
Score = 29.6 bits (65), Expect = 2.1
Identities = 28/79 (35%), Positives = 32/79 (40%), Gaps = 16/79 (20%)
Query: 136 GSSFQDLLGDALA-----GPPRAPGRSGWPAGGAPGSPI-PSPPG-PGDDLCSDLEEAPE 188
GS DL+G GPP PG G P G PG+ + PPG PG+D P
Sbjct: 604 GSGSGDLVGSEQLLRGPPGPPGPPGLPGIP--GKPGTDVFMGPPGSPGED-------GPA 654
Query: 189 AELSQAPAEGPDLVPAALG 207
E EG V A G
Sbjct: 655 GEPGPPGPEGQPGVDGATG 673
>gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]
Length = 1838
Score = 35.8 bits (81), Expect = 0.030
Identities = 23/65 (35%), Positives = 31/65 (47%), Gaps = 7/65 (10%)
Query: 149 GPPRAPGRSGWPAG-----GAPGSPIPS-PPGPGDDLCSDLEEAPEAELSQAPAEGPDLV 202
GP +PG G PAG G PG P P PPGP + + E+ P+ + +GP +
Sbjct: 1084 GPAGSPGERG-PAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGL 1142
Query: 203 PAALG 207
P G
Sbjct: 1143 PGPAG 1147
Score = 32.0 bits (71), Expect = 0.43
Identities = 15/36 (41%), Positives = 19/36 (52%)
Query: 140 QDLLGDALAGPPRAPGRSGWPAGGAPGSPIPSPPGP 175
QD + + + GP G+ G PA PG I PPGP
Sbjct: 438 QDTIYEGIGGPRGEKGQKGEPAIIEPGMLIEGPPGP 473
Score = 29.6 bits (65), Expect = 2.1
Identities = 23/73 (31%), Positives = 31/73 (42%), Gaps = 4/73 (5%)
Query: 148 AGPPRAPGRSGWPAG--GAPGSP-IPSPPGPGDDLCSDLEEAPEAELSQAPAEGPDLVPA 204
+GP G +G P+G G PG P +P PPGP S P+ E GP P
Sbjct: 1512 SGPKGEQGITG-PSGPIGPPGPPGLPGPPGPKGAKGSSGPTGPKGEAGHPGPPGPPGPPG 1570
Query: 205 ALGSLTTAQIARS 217
+ Q +R+
Sbjct: 1571 EVIQPLPIQASRT 1583
>gi|6912492 mitogen-activated protein kinase 8 interacting protein 2
isoform 1 [Homo sapiens]
Length = 824
Score = 35.8 bits (81), Expect = 0.030
Identities = 30/81 (37%), Positives = 37/81 (45%), Gaps = 5/81 (6%)
Query: 123 LLNHLLESMPLREGSSFQDLLGDALAGPPRAPGRSGWPAGGA--PGSPIPSPPGPGDDLC 180
LL++L+ M + EGSS G L+ PR PG PAGGA + GPG
Sbjct: 350 LLSNLVSRM-ISEGSSPIRCPGQCLSPAPRPPGEPVSPAGGAAQDSQDPEAAAGPGGVEL 408
Query: 181 SDLEE--APEAELSQAPAEGP 199
D+E AP AP GP
Sbjct: 409 VDMETLCAPPPPAPAAPRPGP 429
>gi|7706537 mitogen-activated protein kinase 8 interacting protein 2
isoform 2 [Homo sapiens]
Length = 797
Score = 35.8 bits (81), Expect = 0.030
Identities = 30/81 (37%), Positives = 37/81 (45%), Gaps = 5/81 (6%)
Query: 123 LLNHLLESMPLREGSSFQDLLGDALAGPPRAPGRSGWPAGGA--PGSPIPSPPGPGDDLC 180
LL++L+ M + EGSS G L+ PR PG PAGGA + GPG
Sbjct: 323 LLSNLVSRM-ISEGSSPIRCPGQCLSPAPRPPGEPVSPAGGAAQDSQDPEAAAGPGGVEL 381
Query: 181 SDLEE--APEAELSQAPAEGP 199
D+E AP AP GP
Sbjct: 382 VDMETLCAPPPPAPAAPRPGP 402
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 35.4 bits (80), Expect = 0.039
Identities = 31/87 (35%), Positives = 36/87 (41%), Gaps = 18/87 (20%)
Query: 144 GDALAGPP-----RAPGRSGWPAG--------GAPGSPIPSPP--GPG--DDLCSDLE-E 185
G A A PP A + W G GAPG+P+P PP GPG D LC+ E E
Sbjct: 651 GGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETE 710
Query: 186 APEAELSQAPAEGPDLVPAALGSLTTA 212
PE+ A P P G A
Sbjct: 711 GPESATPAPGALDPGPSPGTSGGKAAA 737
Score = 28.5 bits (62), Expect = 4.8
Identities = 22/57 (38%), Positives = 25/57 (43%), Gaps = 5/57 (8%)
Query: 150 PPRAPGRSGWPAGGAPGSPIPSPPGPGDDLCSDLEEAPEA---ELSQAPAEGPDLVP 203
PP+AP P AP SP SP P L + +AP A L QAP P P
Sbjct: 393 PPQAPPALALPPLQAPPSPPASP--PLSPLATPSPQAPNALAVHLLQAPFSPPPSPP 447
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
Length = 1124
Score = 35.4 bits (80), Expect = 0.039
Identities = 31/87 (35%), Positives = 36/87 (41%), Gaps = 18/87 (20%)
Query: 144 GDALAGPP-----RAPGRSGWPAG--------GAPGSPIPSPP--GPG--DDLCSDLE-E 185
G A A PP A + W G GAPG+P+P PP GPG D LC+ E E
Sbjct: 920 GGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETE 979
Query: 186 APEAELSQAPAEGPDLVPAALGSLTTA 212
PE+ A P P G A
Sbjct: 980 GPESATPAPGALDPGPSPGTSGGKAAA 1006
Score = 28.5 bits (62), Expect = 4.8
Identities = 22/57 (38%), Positives = 25/57 (43%), Gaps = 5/57 (8%)
Query: 150 PPRAPGRSGWPAGGAPGSPIPSPPGPGDDLCSDLEEAPEA---ELSQAPAEGPDLVP 203
PP+AP P AP SP SP P L + +AP A L QAP P P
Sbjct: 618 PPQAPPXLALPPLQAPPSPPASP--PLSPLATPSPQAPNALAVHLLQAPFSPPPSPP 672
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 35.4 bits (80), Expect = 0.039
Identities = 31/87 (35%), Positives = 36/87 (41%), Gaps = 18/87 (20%)
Query: 144 GDALAGPP-----RAPGRSGWPAG--------GAPGSPIPSPP--GPG--DDLCSDLE-E 185
G A A PP A + W G GAPG+P+P PP GPG D LC+ E E
Sbjct: 612 GGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETE 671
Query: 186 APEAELSQAPAEGPDLVPAALGSLTTA 212
PE+ A P P G A
Sbjct: 672 GPESATPAPGALDPGPSPGTSGGKAAA 698
Score = 28.5 bits (62), Expect = 4.8
Identities = 22/57 (38%), Positives = 25/57 (43%), Gaps = 5/57 (8%)
Query: 150 PPRAPGRSGWPAGGAPGSPIPSPPGPGDDLCSDLEEAPEA---ELSQAPAEGPDLVP 203
PP+AP P AP SP SP P L + +AP A L QAP P P
Sbjct: 354 PPQAPPALALPPLQAPPSPPASP--PLSPLATPSPQAPNALAVHLLQAPFSPPPSPP 408
>gi|154355000 KH-type splicing regulatory protein [Homo sapiens]
Length = 711
Score = 35.4 bits (80), Expect = 0.039
Identities = 17/29 (58%), Positives = 17/29 (58%), Gaps = 1/29 (3%)
Query: 149 GPPRAPGRSGWPAGGAPGSPIPSPPGPGD 177
GPP P G AGGA G P P PPG GD
Sbjct: 12 GPP-PPAGGGGGAGGAGGGPPPGPPGAGD 39
Score = 28.1 bits (61), Expect = 6.2
Identities = 16/37 (43%), Positives = 17/37 (45%), Gaps = 3/37 (8%)
Query: 141 DLLGDALAGPPRAPGRSGWPAGG---APGSPIPSPPG 174
DLL +GPP PG G P GG G PPG
Sbjct: 388 DLLQSLRSGPPGPPGGPGMPPGGRGRGRGQGNWGPPG 424
>gi|27477113 sterol regulatory element-binding transcription factor
2 [Homo sapiens]
Length = 1141
Score = 35.4 bits (80), Expect = 0.039
Identities = 15/46 (32%), Positives = 29/46 (63%)
Query: 24 GDRKARKPLVEKKRRARINESLQELRLLLAGAEAKLENAEVLELTV 69
G+R+ ++EK+ R+ IN+ + EL+ L+ G +AK+ + VL +
Sbjct: 329 GERRTTHNIIEKRYRSSINDKIIELKDLVMGTDAKMHKSGVLRKAI 374
>gi|110556644 zinc finger protein, multitype 1 [Homo sapiens]
Length = 1006
Score = 35.4 bits (80), Expect = 0.039
Identities = 31/81 (38%), Positives = 35/81 (43%), Gaps = 9/81 (11%)
Query: 127 LLESMPLREGSSFQDLLGDALAGP---PRAPGRSG-WPAGGAPGSPIPSPPGPGDDLCSD 182
LLE L G LLG LAGP R P G PA SP P GP D L +
Sbjct: 869 LLEHFRLAHGL----LLGAPLAGPGVEARTPADRGPSPAPAPAASPQPGSRGPRDGLGPE 924
Query: 183 LEEAPEAELSQAPAEGPDLVP 203
+E P +PA P+ VP
Sbjct: 925 PQEPPPGP-PPSPAAAPEAVP 944
Score = 31.2 bits (69), Expect = 0.74
Identities = 21/57 (36%), Positives = 23/57 (40%), Gaps = 8/57 (14%)
Query: 148 AGPPRAPG--------RSGWPAGGAPGSPIPSPPGPGDDLCSDLEEAPEAELSQAPA 196
A PP PG R G +G PG PGP D DL + P L APA
Sbjct: 754 APPPPPPGHAPAPESPRPGSGSGSGPGLAPARSPGPAADGPIDLSKKPRRPLPGAPA 810
>gi|169207312 PREDICTED: hypothetical protein [Homo sapiens]
Length = 414
Score = 35.0 bits (79), Expect = 0.051
Identities = 20/60 (33%), Positives = 29/60 (48%), Gaps = 6/60 (10%)
Query: 151 PRAPGRSGWPAGGAPGSPIPSP----PGPGDDLCSDLEEAPEAELS--QAPAEGPDLVPA 204
P P + WPA GAPG+P P+ PGP S +E ++ + EG +L P+
Sbjct: 322 PAPPAPTAWPAAGAPGAPNPAESRRGPGPAQGPPSRRDEPRRVVIAARECGREGSELPPS 381
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.132 0.395
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,383,149
Number of Sequences: 37866
Number of extensions: 618293
Number of successful extensions: 5742
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 119
Number of HSP's successfully gapped in prelim test: 396
Number of HSP's that attempted gapping in prelim test: 4476
Number of HSP's gapped (non-prelim): 1643
length of query: 222
length of database: 18,247,518
effective HSP length: 98
effective length of query: 124
effective length of database: 14,536,650
effective search space: 1802544600
effective search space used: 1802544600
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.