BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|21735492 protein phosphatase 1, regulatory (inhibitor) subunit 1B isoform 1 [Homo sapiens] (204 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|21735492 protein phosphatase 1, regulatory (inhibitor) subuni... 418 e-117 gi|31415880 protein phosphatase 1, regulatory (inhibitor) subuni... 345 1e-95 gi|122937386 protein phosphatase 1, regulatory (inhibitor) subun... 77 1e-14 gi|155030238 protein phosphatase 1, regulatory (inhibitor) subun... 63 2e-10 gi|17975763 myelin transcription factor 1 [Homo sapiens] 51 6e-07 gi|58761548 tau tubulin kinase 1 [Homo sapiens] 49 2e-06 gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 49 3e-06 gi|100816397 MYST histone acetyltransferase (monocytic leukemia)... 49 4e-06 gi|118600967 shroom family member 4 [Homo sapiens] 48 7e-06 gi|4504487 histidine rich calcium binding protein precursor [Hom... 47 9e-06 gi|114205399 cyclic nucleotide gated channel beta 1 isoform a [H... 47 1e-05 gi|4506411 Ran GTPase activating protein 1 [Homo sapiens] 47 1e-05 gi|211904182 DDB1 and CUL4 associated factor 8-like 2 [Homo sapi... 46 3e-05 gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof... 46 3e-05 gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isof... 46 3e-05 gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isof... 46 3e-05 gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isof... 46 3e-05 gi|16332360 cell division cycle 2-like 1 (PITSLRE proteins) isof... 46 3e-05 gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isof... 46 3e-05 gi|21735415 centromere protein B [Homo sapiens] 45 3e-05 gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens] 45 3e-05 gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens] 45 3e-05 gi|66792814 retrotransposon gag domain containing 4 [Homo sapiens] 45 4e-05 gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens] 45 6e-05 gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens] 45 6e-05 gi|115529449 upstream binding transcription factor, RNA polymera... 45 6e-05 gi|115529451 upstream binding transcription factor, RNA polymera... 45 6e-05 gi|7657671 upstream binding transcription factor, RNA polymerase... 45 6e-05 gi|156142199 euchromatic histone-lysine N-methyltransferase 2 is... 44 7e-05 gi|156142197 euchromatic histone-lysine N-methyltransferase 2 is... 44 7e-05 >gi|21735492 protein phosphatase 1, regulatory (inhibitor) subunit 1B isoform 1 [Homo sapiens] Length = 204 Score = 418 bits (1075), Expect = e-117 Identities = 204/204 (100%), Positives = 204/204 (100%) Query: 1 MDPKDRKKIQFSVPAPPSQLDPRQVEMIRRRRPTPAMLFRLSEHSSPEEEASPHQRASGE 60 MDPKDRKKIQFSVPAPPSQLDPRQVEMIRRRRPTPAMLFRLSEHSSPEEEASPHQRASGE Sbjct: 1 MDPKDRKKIQFSVPAPPSQLDPRQVEMIRRRRPTPAMLFRLSEHSSPEEEASPHQRASGE 60 Query: 61 GHHLKSKRPNPCAYTPPSLKAVQRIAESHLQSISNLNENQASEEEDELGELRELGYPREE 120 GHHLKSKRPNPCAYTPPSLKAVQRIAESHLQSISNLNENQASEEEDELGELRELGYPREE Sbjct: 61 GHHLKSKRPNPCAYTPPSLKAVQRIAESHLQSISNLNENQASEEEDELGELRELGYPREE 120 Query: 121 DEEEEEDDEEEEEEEDSQAEVLKVIRQSAGQKTTCGQGLEGPWERPPPLDESERDGGSED 180 DEEEEEDDEEEEEEEDSQAEVLKVIRQSAGQKTTCGQGLEGPWERPPPLDESERDGGSED Sbjct: 121 DEEEEEDDEEEEEEEDSQAEVLKVIRQSAGQKTTCGQGLEGPWERPPPLDESERDGGSED 180 Query: 181 QVEDPALSEPGEEPQRPSPSEPGT 204 QVEDPALSEPGEEPQRPSPSEPGT Sbjct: 181 QVEDPALSEPGEEPQRPSPSEPGT 204 >gi|31415880 protein phosphatase 1, regulatory (inhibitor) subunit 1B isoform 2 [Homo sapiens] Length = 168 Score = 345 bits (886), Expect = 1e-95 Identities = 168/168 (100%), Positives = 168/168 (100%) Query: 37 MLFRLSEHSSPEEEASPHQRASGEGHHLKSKRPNPCAYTPPSLKAVQRIAESHLQSISNL 96 MLFRLSEHSSPEEEASPHQRASGEGHHLKSKRPNPCAYTPPSLKAVQRIAESHLQSISNL Sbjct: 1 MLFRLSEHSSPEEEASPHQRASGEGHHLKSKRPNPCAYTPPSLKAVQRIAESHLQSISNL 60 Query: 97 NENQASEEEDELGELRELGYPREEDEEEEEDDEEEEEEEDSQAEVLKVIRQSAGQKTTCG 156 NENQASEEEDELGELRELGYPREEDEEEEEDDEEEEEEEDSQAEVLKVIRQSAGQKTTCG Sbjct: 61 NENQASEEEDELGELRELGYPREEDEEEEEDDEEEEEEEDSQAEVLKVIRQSAGQKTTCG 120 Query: 157 QGLEGPWERPPPLDESERDGGSEDQVEDPALSEPGEEPQRPSPSEPGT 204 QGLEGPWERPPPLDESERDGGSEDQVEDPALSEPGEEPQRPSPSEPGT Sbjct: 121 QGLEGPWERPPPLDESERDGGSEDQVEDPALSEPGEEPQRPSPSEPGT 168 >gi|122937386 protein phosphatase 1, regulatory (inhibitor) subunit 1C [Homo sapiens] Length = 109 Score = 76.6 bits (187), Expect = 1e-14 Identities = 43/113 (38%), Positives = 58/113 (51%), Gaps = 8/113 (7%) Query: 1 MDPKDRKKIQFSVPAPPSQLDPRQVEMIRRRRPTPAMLFRLSEHSSPEEEASPHQRASGE 60 M+P KKIQF+VP SQ+ P E IR+RRPTPA L L+EH+ PE + GE Sbjct: 1 MEPNSPKKIQFAVPVFQSQIAPEAAEQIRKRRPTPASLVILNEHNPPEIDDKRGPNTQGE 60 Query: 61 GHHLKSKRPNPCAYTPPSLKAVQRIAESHLQSISNLNENQASEEEDELGELRE 113 + K+ YTPP++K V+ + NE+ EEE+ E E Sbjct: 61 LQNASPKQRKQSVYTPPTIKGVKH--------LKGQNESAFPEEEEGTNEREE 105 >gi|155030238 protein phosphatase 1, regulatory (inhibitor) subunit 1A [Homo sapiens] Length = 171 Score = 62.8 bits (151), Expect = 2e-10 Identities = 45/124 (36%), Positives = 58/124 (46%), Gaps = 15/124 (12%) Query: 7 KKIQFSVPAPPSQLDPRQVEMIRRRRPTPAMLFRLSEHSSPE--EEASPHQRASGEGHHL 64 +KIQF+VP LDP E IRRRRPTPA L S+ SSPE E+ P+ HL Sbjct: 8 RKIQFTVPLLEPHLDPEAAEQIRRRRPTPATLVLTSDQSSPEIDEDRIPNP-------HL 60 Query: 65 KS------KRPNPCAYTPPSLKAVQRIAESHLQSISNLNENQASEEEDELGELRELGYPR 118 KS ++ P++K +Q + E HL E + + E E R G P Sbjct: 61 KSTLAMSPRQRKKMTRITPTMKELQMMVEHHLGQQQQGEEPEGAAESTGTQESRPPGIPD 120 Query: 119 EEDE 122 E E Sbjct: 121 TEVE 124 >gi|17975763 myelin transcription factor 1 [Homo sapiens] Length = 1121 Score = 51.2 bits (121), Expect = 6e-07 Identities = 31/83 (37%), Positives = 45/83 (54%), Gaps = 4/83 (4%) Query: 88 SHLQSISNLNENQASEEEDELGELRELGYPREEDEEEEEDDEEEEEEEDSQAEVLKVIRQ 147 SH + E + EEEDE E E EE+EEEEE++EEEEEEE+ +A + ++ Sbjct: 256 SHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQE 315 Query: 148 ----SAGQKTTCGQGLEGPWERP 166 ++ QK +G E P +P Sbjct: 316 DTSHTSAQKAPELRGPESPSPKP 338 Score = 47.0 bits (110), Expect = 1e-05 Identities = 26/65 (40%), Positives = 36/65 (55%) Query: 76 PPSLKAVQRIAESHLQSISNLNENQASEEEDELGELRELGYPREEDEEEEEDDEEEEEEE 135 P SL+ S + I + E EEE+E E + EE+EEEEE++EEEEEEE Sbjct: 237 PQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEE 296 Query: 136 DSQAE 140 + + E Sbjct: 297 EEEEE 301 Score = 47.0 bits (110), Expect = 1e-05 Identities = 34/86 (39%), Positives = 46/86 (53%), Gaps = 8/86 (9%) Query: 93 ISNLNENQASEEEDELGELRELGYPREEDEEEEEDDEEEEEEEDSQAE-----VLKVIRQ 147 +S+ E++ EEE+E E E EE+EEEEE++EEEEEEE+ + E VI Q Sbjct: 255 LSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQ 314 Query: 148 SAGQKTTCGQG--LEGPWERPPPLDE 171 T+ + L GP E P P E Sbjct: 315 EDTSHTSAQKAPELRGP-ESPSPKPE 339 >gi|58761548 tau tubulin kinase 1 [Homo sapiens] Length = 1321 Score = 49.3 bits (116), Expect = 2e-06 Identities = 30/75 (40%), Positives = 41/75 (54%), Gaps = 12/75 (16%) Query: 79 LKAVQRIAESHL------------QSISNLNENQASEEEDELGELRELGYPREEDEEEEE 126 L V+R+ SH+ Q +N E + EEEDE E + EE+EEEEE Sbjct: 702 LNRVRRVGFSHMLLTTPQVPLAPVQPQANGKEEEEEEEEDEEEEEEDEEEEEEEEEEEEE 761 Query: 127 DDEEEEEEEDSQAEV 141 ++EEEEEEE++ A V Sbjct: 762 EEEEEEEEEEAAAAV 776 >gi|155030232 proline, glutamic acid and leucine rich protein 1 [Homo sapiens] Length = 1130 Score = 48.9 bits (115), Expect = 3e-06 Identities = 43/131 (32%), Positives = 60/131 (45%), Gaps = 13/131 (9%) Query: 76 PPSLKAVQRIAESHLQSISNLNENQASEEEDELGELRELGYPREEDEEEEEDDEEE--EE 133 PP+L E L I+ + ++ EEE+E E E EED EEEE+DEEE EE Sbjct: 871 PPAL-------EEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEE 923 Query: 134 EEDSQAEVLKVIRQSAGQKTTCGQGLEGPWERPPPLDESE--RDGGSEDQVEDPALSEPG 191 EE+ + E + + G+ + E E L+E E G + +VE+ A P Sbjct: 924 EEEEEEEFEEEFEEEEGELEE--EEEEEDEEEEEELEEVEDLEFGTAGGEVEEGAPPPPT 981 Query: 192 EEPQRPSPSEP 202 P P P P Sbjct: 982 LPPALPPPESP 992 Score = 43.1 bits (100), Expect = 2e-04 Identities = 35/116 (30%), Positives = 50/116 (43%), Gaps = 9/116 (7%) Query: 87 ESHLQSISNLNENQASEEEDELGELRELGYPREEDEEEEEDDEEEEEEEDSQAEVLKVIR 146 E + + E E E+E GEL E EE+E+EEE++E EE E+ + Sbjct: 918 EEYFEEEEEEEEEFEEEFEEEEGELEE----EEEEEDEEEEEELEEVEDLEFGTAGGEVE 973 Query: 147 QSAGQKTTCGQGLEGPWERPPPLDESERDGGSEDQVEDPALSEPGEEPQRPSPSEP 202 + A T L P P E E + G +VE EPG E +R + + P Sbjct: 974 EGAPPPPTLPPALPPPESPPKVQPEPEPEPGLLLEVE-----EPGTEEERGADTAP 1024 Score = 41.2 bits (95), Expect = 6e-04 Identities = 43/149 (28%), Positives = 56/149 (37%), Gaps = 42/149 (28%) Query: 97 NENQASEEEDELGELRELGYPREEDEEEEEDDEEEEEEEDSQAEVLKV--------IRQS 148 +E + EEE+E E E + EE E EEE++EE+EEEE+ EV + + + Sbjct: 916 DEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVEDLEFGTAGGEVEEG 975 Query: 149 AGQKTTCGQGLEGPWERPP------------------PLDESER---------------D 175 A T L P E PP P E ER Sbjct: 976 APPPPTLPPALPPP-ESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAPEALPSQ 1034 Query: 176 GGSEDQVEDPALSEPGEEPQRPSPSEPGT 204 G E + E PA P +E PS P T Sbjct: 1035 GEVEREGESPAAGPPPQELVEEEPSAPPT 1063 Score = 28.9 bits (63), Expect = 3.2 Identities = 40/144 (27%), Positives = 57/144 (39%), Gaps = 33/144 (22%) Query: 14 PAPPSQLDPRQVEMIRRRRPTPAMLFRLSEHSSPEE-----------EASPHQRASGEGH 62 PA P P +V+ P P +L + E + EE EA P Q GE Sbjct: 984 PALPPPESPPKVQP--EPEPEPGLLLEVEEPGTEEERGADTAPTLAPEALPSQ---GE-- 1036 Query: 63 HLKSKRPNPCAYTPPSLKAVQRIAESHLQSISNLNENQASEEEDELGELRELGYPREEDE 122 ++ + +P A PP Q + E + L EEE E G + P E Sbjct: 1037 -VEREGESPAAGPPP-----QELVEEEPSAPPTL-----LEEETEDGSDKVQPPPETPAE 1085 Query: 123 EEEEDDEE----EEEEEDSQAEVL 142 EE E + E +E+E+D A +L Sbjct: 1086 EEMETETEAEALQEKEQDDTAAML 1109 >gi|100816397 MYST histone acetyltransferase (monocytic leukemia) 4 [Homo sapiens] Length = 2073 Score = 48.5 bits (114), Expect = 4e-06 Identities = 37/103 (35%), Positives = 50/103 (48%), Gaps = 7/103 (6%) Query: 40 RLSEHSS---PEEEASPHQRASGEGHHLKSKRPNPCAYTPPSLKAVQRIAESHLQSISNL 96 RL E +S EE+ RA+ K + N ++P S L +S Sbjct: 1010 RLMEQASCWEKEEQEILSTRANSRQSPAKVQSKNKYLHSPESRPVTGE--RGQLLELSKE 1067 Query: 97 NENQASEEEDELGELRELGYPREEDEEEEEDDEEEEEEEDSQA 139 + + EEEDE E E EEDEEEEE++EEEEEEE+ Q+ Sbjct: 1068 SSEEEEEEEDEEEEEEE--EEEEEDEEEEEEEEEEEEEENIQS 1108 Score = 46.6 bits (109), Expect = 1e-05 Identities = 44/171 (25%), Positives = 73/171 (42%), Gaps = 25/171 (14%) Query: 39 FRLSEHSSPEEEASPHQRASGEGHHLKSKRPNPCAYTPPSLKAVQRIAESHLQSISNLNE 98 F+L+ ++ PE P ++ + E + K + +P ++ + + E+ +++ E Sbjct: 1269 FKLNLYTPPETPMEPDEQVTVE----EQKETSEGKTSPSPIRIEEEVKETG-EALLPQEE 1323 Query: 99 NQASEE------EDELGELRE--LGYPREEDEEEEEDDEEEEEEEDSQAEVLKVIRQSAG 150 N+ E GE E L P EE+EEEEE++EEEEEEE + E G Sbjct: 1324 NRREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEEEGEEEE-------GGG 1376 Query: 151 QKTTCGQGLEGPWERPPPLDESERDGGSEDQVEDPALSEPGEEPQRPSPSE 201 G + + P + + D D E E EE + PS +E Sbjct: 1377 NVEKDPDGAKSQEKEEPEISTEKEDSARLDDHE-----EEEEEDEEPSHNE 1422 Score = 43.9 bits (102), Expect = 1e-04 Identities = 25/64 (39%), Positives = 39/64 (60%), Gaps = 1/64 (1%) Query: 78 SLKAVQRIAESHLQSISN-LNENQASEEEDELGELRELGYPREEDEEEEEDDEEEEEEED 136 S +A R + + +QS + L+ ++ E G+L EL E+EEEEED+EEEEEEE+ Sbjct: 1027 STRANSRQSPAKVQSKNKYLHSPESRPVTGERGQLLELSKESSEEEEEEEDEEEEEEEEE 1086 Query: 137 SQAE 140 + + Sbjct: 1087 EEED 1090 Score = 32.0 bits (71), Expect = 0.37 Identities = 15/38 (39%), Positives = 22/38 (57%) Query: 103 EEEDELGELRELGYPREEDEEEEEDDEEEEEEEDSQAE 140 +EE E+ +E ++ EEEEE+DEE ED A+ Sbjct: 1390 KEEPEISTEKEDSARLDDHEEEEEEDEEPSHNEDHDAD 1427 Score = 28.9 bits (63), Expect = 3.2 Identities = 27/103 (26%), Positives = 43/103 (41%), Gaps = 6/103 (5%) Query: 43 EHSSPEEEASPHQRASGEGHHLKSKRPNPCAYTPPSLKAVQRIAESHLQSISNLNENQAS 102 E EEE + EG K P+ S + + + + + L++++ Sbjct: 1356 EEEEEEEEEEEEEGEEEEGGGNVEKDPDGAK----SQEKEEPEISTEKEDSARLDDHEEE 1411 Query: 103 EEEDELGELRELGYPREEDEEEEEDDEEEEEE--EDSQAEVLK 143 EEEDE E +ED+ E E E+EE +S EVL+ Sbjct: 1412 EEEDEEPSHNEDHDADDEDDSHMESAEVEKEELPRESFKEVLE 1454 Score = 28.1 bits (61), Expect = 5.4 Identities = 15/51 (29%), Positives = 28/51 (54%), Gaps = 1/51 (1%) Query: 98 ENQASEEEDELGELRELGYPREEDEEE-EEDDEEEEEEEDSQAEVLKVIRQ 147 E + S E+++ L + EEDEE +D + ++E+DS E +V ++ Sbjct: 1392 EPEISTEKEDSARLDDHEEEEEEDEEPSHNEDHDADDEDDSHMESAEVEKE 1442 >gi|118600967 shroom family member 4 [Homo sapiens] Length = 1493 Score = 47.8 bits (112), Expect = 7e-06 Identities = 33/114 (28%), Positives = 48/114 (42%), Gaps = 13/114 (11%) Query: 76 PPSLKAVQRIAESHLQSISNLNENQASEEEDELGELRELGYPREEDEEEEEDDEEEEEEE 135 PP+ + + + Q + Q EEE EE+EEEEE++EEEEEE Sbjct: 1106 PPNWEKYRLFRAAQQQKQQQQQQKQQEEEE-------------EEEEEEEEEEEEEEEEA 1152 Query: 136 DSQAEVLKVIRQSAGQKTTCGQGLEGPWERPPPLDESERDGGSEDQVEDPALSE 189 + + E L S+ +C E E+P PL +G + PA E Sbjct: 1153 EEEEEELPPQYFSSETSGSCALNPEEVLEQPQPLSFGHLEGSRQGSQSVPAEQE 1206 >gi|4504487 histidine rich calcium binding protein precursor [Homo sapiens] Length = 699 Score = 47.4 bits (111), Expect = 9e-06 Identities = 38/112 (33%), Positives = 55/112 (49%), Gaps = 11/112 (9%) Query: 103 EEEDELGELRELGYPREEDEEEEEDDEEEEEEEDSQ-----AEV-LKVIRQSAGQKTTCG 156 ++EDE E G ++EEEEED EEEEEEED + AEV + + ++ Sbjct: 515 DQEDEEDEEEGHGLSLNQEEEEEEDKEEEEEEEDEERREERAEVGAPLSPDHSEEEEEEE 574 Query: 157 QGLEGPWER----PPPLDESERDGGSEDQVEDPALSEPGEEPQRPSPSEPGT 204 +GLE R P PLD E GG+ + E + P ++ Q +PG+ Sbjct: 575 EGLEEDEPRFTIIPNPLDRREEAGGASSEEESGEDTGP-QDAQEYGNYQPGS 625 Score = 42.0 bits (97), Expect = 4e-04 Identities = 40/146 (27%), Positives = 56/146 (38%), Gaps = 29/146 (19%) Query: 44 HSSPEEEASPHQRASGEGHHLKSKRPNPCAYTPPSLKAVQRIAESHLQSISNLNENQASE 103 H S + E S R HHL S R SH + +E +SE Sbjct: 137 HGSEDTEDSAEHR-----HHLPSHR-------------------SHSHQDEDEDEVVSSE 172 Query: 104 EEDELGELRELGYPREEDEEEEEDDEEEEEEEDS-----QAEVLKVIRQSAGQKTTCGQG 158 + G+ E+DE EEE++EEEEEEE S QA + + + G Sbjct: 173 HHHHILRHGHRGHDGEDDEGEEEEEEEEEEEEASTEYGHQAHRHRGHGSEEDEDVSDGHH 232 Query: 159 LEGPWERPPPLDESERDGGSEDQVED 184 GP R +E + D +D +D Sbjct: 233 HHGPSHRHQGHEEDDDDDDDDDDDDD 258 Score = 30.8 bits (68), Expect = 0.83 Identities = 21/107 (19%), Positives = 47/107 (43%), Gaps = 9/107 (8%) Query: 97 NENQASEEEDELGELRELGYP------REEDEEEEEDDEEEEEEEDSQAEVLKVIRQSAG 150 + SEE++++ + P EED+++++DD+++++++D E + G Sbjct: 216 HRGHGSEEDEDVSDGHHHHGPSHRHQGHEEDDDDDDDDDDDDDDDDVSIEYRHQAHRHQG 275 Query: 151 QKTTCGQGL-EGPWERPPPLDESERDGGSEDQVEDPALSEPGEEPQR 196 + + +G R P R +D +D +E G + R Sbjct: 276 HGIEEDEDVSDGHHHRDP--SHRHRSHEEDDNDDDDVSTEYGHQAHR 320 >gi|114205399 cyclic nucleotide gated channel beta 1 isoform a [Homo sapiens] Length = 1251 Score = 47.0 bits (110), Expect = 1e-05 Identities = 33/107 (30%), Positives = 53/107 (49%), Gaps = 12/107 (11%) Query: 101 ASEEEDELGELRELGYPREEDEEEEEDDEEEEEEEDSQAEVLKVIRQS-------AGQKT 153 A EEE++ E R E+E+E+E++EEEEEEE+ + EV +V+ S GQ Sbjct: 332 AYEEENKAVEKMPRELSRIEEEKEDEEEEEEEEEEEEEEEVTEVLLDSCVVSQVGVGQSE 391 Query: 154 TCGQGLEGP-----WERPPPLDESERDGGSEDQVEDPALSEPGEEPQ 195 G + WE + E + ++++ E+ A E +EPQ Sbjct: 392 EDGTRPQSTSDQKLWEEVGEEAKKEAEEKAKEEAEEVAEEEAEKEPQ 438 Score = 30.4 bits (67), Expect = 1.1 Identities = 20/66 (30%), Positives = 33/66 (50%), Gaps = 8/66 (12%) Query: 75 TPPSLKAVQRIAESHLQSISNLNENQASEEEDELGELRELGYPREEDEEEEEDDEEEEEE 134 T P + Q++ E + E +A EE +E+ E EE E+E +D E +EE Sbjct: 395 TRPQSTSDQKLWEEVGEEAKKEAEEKAKEEAEEVAE--------EEAEKEPQDWAETKEE 446 Query: 135 EDSQAE 140 +++AE Sbjct: 447 PEAEAE 452 >gi|4506411 Ran GTPase activating protein 1 [Homo sapiens] Length = 587 Score = 47.0 bits (110), Expect = 1e-05 Identities = 32/112 (28%), Positives = 50/112 (44%), Gaps = 29/112 (25%) Query: 93 ISNLNENQASEEEDELGELRELGYPREEDEEEEEDDEEEEEEEDSQAEVLKVIRQSAGQK 152 +++L++++ EEE+E E E EE++EEEE++EEEEEEE+ Q Sbjct: 354 LASLSDDEDEEEEEEGEEEEEEAEEEEEEDEEEEEEEEEEEEEEPQQR------------ 401 Query: 153 TTCGQGLEGPWERPPPLDESERDGGSEDQVEDPALSEPGEEPQRPSPSEPGT 204 GQG E+ ++ DP EP P P++ T Sbjct: 402 ---GQG--------------EKSATPSRKILDPNTGEPAPVLSSPPPADVST 436 >gi|211904182 DDB1 and CUL4 associated factor 8-like 2 [Homo sapiens] Length = 631 Score = 45.8 bits (107), Expect = 3e-05 Identities = 23/41 (56%), Positives = 30/41 (73%), Gaps = 2/41 (4%) Query: 98 ENQASEEEDELGELRELGYPREEDEEEEEDDEEEEEEEDSQ 138 E EEEDE E++E G EE+EEEEE++EEEEEEE+ + Sbjct: 109 EETEREEEDE--EIQEEGGEEEEEEEEEEEEEEEEEEEEEE 147 Score = 44.7 bits (104), Expect = 6e-05 Identities = 22/41 (53%), Positives = 30/41 (73%), Gaps = 2/41 (4%) Query: 98 ENQASEEEDELGELRELGYPREEDEEEEEDDEEEEEEEDSQ 138 E + EE++E+ E E G EE+EEEEE++EEEEEEE+ Q Sbjct: 110 ETEREEEDEEIQE--EGGEEEEEEEEEEEEEEEEEEEEEEQ 148 Score = 29.3 bits (64), Expect = 2.4 Identities = 30/96 (31%), Positives = 40/96 (41%), Gaps = 22/96 (22%) Query: 92 SISNLNENQASEEED-ELGELRELG-----------YPR--EEDEEEEEDD--------E 129 S N + +Q S ED EL L + YP EE+ E EE+D E Sbjct: 67 STENRSSDQESASEDIELESLEDFEHFLMSGESLFHYPLVGEEETEREEEDEEIQEEGGE 126 Query: 130 EEEEEEDSQAEVLKVIRQSAGQKTTCGQGLEGPWER 165 EEEEEE+ + E + + Q QG G E+ Sbjct: 127 EEEEEEEEEEEEEEEEEEEEEQPRAGPQGSGGNHEQ 162 Score = 27.3 bits (59), Expect = 9.2 Identities = 23/91 (25%), Positives = 37/91 (40%), Gaps = 12/91 (13%) Query: 112 RELGYPREEDEEEEEDDEEEEEEEDSQAEVLKVIRQSAGQKTTCGQGL-------EGPWE 164 R+ G+P + E D +E ED + E L+ G+ L E E Sbjct: 58 RDGGFPNDASTENRSSD-QESASEDIELESLEDFEHF----LMSGESLFHYPLVGEEETE 112 Query: 165 RPPPLDESERDGGSEDQVEDPALSEPGEEPQ 195 R +E + +GG E++ E+ E EE + Sbjct: 113 REEEDEEIQEEGGEEEEEEEEEEEEEEEEEE 143 >gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform 9 [Homo sapiens] Length = 771 Score = 45.8 bits (107), Expect = 3e-05 Identities = 40/127 (31%), Positives = 58/127 (45%), Gaps = 16/127 (12%) Query: 88 SHLQSISNLNENQASEEEDELGELRELGYPREEDEEEEEDDEEEEEEEDSQAEVLKVIRQ 147 S +S S + + + EEE+E E E G EE EEEEE++EEEEEE S +E + Q Sbjct: 266 SSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSE--EASEQ 323 Query: 148 SAGQKTTCGQGLEGPWERP-----PPLDESERDGGSEDQVED---------PALSEPGEE 193 SA + + + E P +RD G ++ E+ AL+E Sbjct: 324 SAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYV 383 Query: 194 PQRPSPS 200 P P+ S Sbjct: 384 PDSPALS 390 Score = 34.3 bits (77), Expect = 0.075 Identities = 37/160 (23%), Positives = 58/160 (36%), Gaps = 12/160 (7%) Query: 50 EASPHQRASGEGHHLKSKRPNPCAYTPP-----------SLKAVQRIAESHLQSISNLNE 98 E S H R E + K K + + +PP K V+ +S+L + Sbjct: 199 EVSAHHRTMREDYSDKVKASH-WSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQD 257 Query: 99 NQASEEEDELGELRELGYPREEDEEEEEDDEEEEEEEDSQAEVLKVIRQSAGQKTTCGQG 158 SE + E +EEEEE++EEEEE S+ + + ++ T Sbjct: 258 ISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNS 317 Query: 159 LEGPWERPPPLDESERDGGSEDQVEDPALSEPGEEPQRPS 198 E + + E E E + E+ L P R S Sbjct: 318 EEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDS 357 >gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isoform 8 [Homo sapiens] Length = 780 Score = 45.8 bits (107), Expect = 3e-05 Identities = 40/127 (31%), Positives = 58/127 (45%), Gaps = 16/127 (12%) Query: 88 SHLQSISNLNENQASEEEDELGELRELGYPREEDEEEEEDDEEEEEEEDSQAEVLKVIRQ 147 S +S S + + + EEE+E E E G EE EEEEE++EEEEEE S +E + Q Sbjct: 275 SSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSE--EASEQ 332 Query: 148 SAGQKTTCGQGLEGPWERP-----PPLDESERDGGSEDQVED---------PALSEPGEE 193 SA + + + E P +RD G ++ E+ AL+E Sbjct: 333 SAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYV 392 Query: 194 PQRPSPS 200 P P+ S Sbjct: 393 PDSPALS 399 Score = 34.3 bits (77), Expect = 0.075 Identities = 37/160 (23%), Positives = 58/160 (36%), Gaps = 12/160 (7%) Query: 50 EASPHQRASGEGHHLKSKRPNPCAYTPP-----------SLKAVQRIAESHLQSISNLNE 98 E S H R E + K K + + +PP K V+ +S+L + Sbjct: 208 EVSAHHRTMREDYSDKVKASH-WSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQD 266 Query: 99 NQASEEEDELGELRELGYPREEDEEEEEDDEEEEEEEDSQAEVLKVIRQSAGQKTTCGQG 158 SE + E +EEEEE++EEEEE S+ + + ++ T Sbjct: 267 ISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNS 326 Query: 159 LEGPWERPPPLDESERDGGSEDQVEDPALSEPGEEPQRPS 198 E + + E E E + E+ L P R S Sbjct: 327 EEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDS 366 >gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isoform 5 [Homo sapiens] Length = 748 Score = 45.8 bits (107), Expect = 3e-05 Identities = 40/127 (31%), Positives = 58/127 (45%), Gaps = 16/127 (12%) Query: 88 SHLQSISNLNENQASEEEDELGELRELGYPREEDEEEEEDDEEEEEEEDSQAEVLKVIRQ 147 S +S S + + + EEE+E E E G EE EEEEE++EEEEEE S +E + Q Sbjct: 243 SSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSE--EASEQ 300 Query: 148 SAGQKTTCGQGLEGPWERP-----PPLDESERDGGSEDQVED---------PALSEPGEE 193 SA + + + E P +RD G ++ E+ AL+E Sbjct: 301 SAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYV 360 Query: 194 PQRPSPS 200 P P+ S Sbjct: 361 PDSPALS 367 Score = 34.3 bits (77), Expect = 0.075 Identities = 37/160 (23%), Positives = 58/160 (36%), Gaps = 12/160 (7%) Query: 50 EASPHQRASGEGHHLKSKRPNPCAYTPP-----------SLKAVQRIAESHLQSISNLNE 98 E S H R E + K K + + +PP K V+ +S+L + Sbjct: 176 EVSAHHRTMREDYSDKVKASH-WSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQD 234 Query: 99 NQASEEEDELGELRELGYPREEDEEEEEDDEEEEEEEDSQAEVLKVIRQSAGQKTTCGQG 158 SE + E +EEEEE++EEEEE S+ + + ++ T Sbjct: 235 ISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNS 294 Query: 159 LEGPWERPPPLDESERDGGSEDQVEDPALSEPGEEPQRPS 198 E + + E E E + E+ L P R S Sbjct: 295 EEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDS 334 >gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isoform 4 [Homo sapiens] Length = 737 Score = 45.8 bits (107), Expect = 3e-05 Identities = 40/127 (31%), Positives = 58/127 (45%), Gaps = 16/127 (12%) Query: 88 SHLQSISNLNENQASEEEDELGELRELGYPREEDEEEEEDDEEEEEEEDSQAEVLKVIRQ 147 S +S S + + + EEE+E E E G EE EEEEE++EEEEEE S +E + Q Sbjct: 232 SSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSE--EASEQ 289 Query: 148 SAGQKTTCGQGLEGPWERP-----PPLDESERDGGSEDQVED---------PALSEPGEE 193 SA + + + E P +RD G ++ E+ AL+E Sbjct: 290 SAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYV 349 Query: 194 PQRPSPS 200 P P+ S Sbjct: 350 PDSPALS 356 Score = 34.3 bits (77), Expect = 0.075 Identities = 37/160 (23%), Positives = 58/160 (36%), Gaps = 12/160 (7%) Query: 50 EASPHQRASGEGHHLKSKRPNPCAYTPP-----------SLKAVQRIAESHLQSISNLNE 98 E S H R E + K K + + +PP K V+ +S+L + Sbjct: 165 EVSAHHRTMREDYSDKVKASH-WSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQD 223 Query: 99 NQASEEEDELGELRELGYPREEDEEEEEDDEEEEEEEDSQAEVLKVIRQSAGQKTTCGQG 158 SE + E +EEEEE++EEEEE S+ + + ++ T Sbjct: 224 ISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNS 283 Query: 159 LEGPWERPPPLDESERDGGSEDQVEDPALSEPGEEPQRPS 198 E + + E E E + E+ L P R S Sbjct: 284 EEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDS 323 >gi|16332360 cell division cycle 2-like 1 (PITSLRE proteins) isoform 3 [Homo sapiens] Length = 526 Score = 45.8 bits (107), Expect = 3e-05 Identities = 40/127 (31%), Positives = 58/127 (45%), Gaps = 16/127 (12%) Query: 88 SHLQSISNLNENQASEEEDELGELRELGYPREEDEEEEEDDEEEEEEEDSQAEVLKVIRQ 147 S +S S + + + EEE+E E E G EE EEEEE++EEEEEE S +E + Q Sbjct: 21 SSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSE--EASEQ 78 Query: 148 SAGQKTTCGQGLEGPWERP-----PPLDESERDGGSEDQVED---------PALSEPGEE 193 SA + + + E P +RD G ++ E+ AL+E Sbjct: 79 SAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYV 138 Query: 194 PQRPSPS 200 P P+ S Sbjct: 139 PDSPALS 145 Score = 33.9 bits (76), Expect = 0.098 Identities = 26/106 (24%), Positives = 42/106 (39%) Query: 93 ISNLNENQASEEEDELGELRELGYPREEDEEEEEDDEEEEEEEDSQAEVLKVIRQSAGQK 152 +S+L + SE + E +EEEEE++EEEEE S+ + + ++ Sbjct: 7 LSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEE 66 Query: 153 TTCGQGLEGPWERPPPLDESERDGGSEDQVEDPALSEPGEEPQRPS 198 T E + + E E E + E+ L P R S Sbjct: 67 ETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDS 112 Score = 33.9 bits (76), Expect = 0.098 Identities = 23/60 (38%), Positives = 31/60 (51%), Gaps = 10/60 (16%) Query: 88 SHLQSISNLNENQASEEEDELGELRELGYPREEDEEEEEDD---------EEEEEEEDSQ 138 S LQ IS+ +E + S E E EE+EEEEE++ EEEEEEE+ + Sbjct: 8 SDLQDISD-SERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEE 66 >gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isoform 2 [Homo sapiens] Length = 782 Score = 45.8 bits (107), Expect = 3e-05 Identities = 40/127 (31%), Positives = 58/127 (45%), Gaps = 16/127 (12%) Query: 88 SHLQSISNLNENQASEEEDELGELRELGYPREEDEEEEEDDEEEEEEEDSQAEVLKVIRQ 147 S +S S + + + EEE+E E E G EE EEEEE++EEEEEE S +E + Q Sbjct: 277 SSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSE--EASEQ 334 Query: 148 SAGQKTTCGQGLEGPWERP-----PPLDESERDGGSEDQVED---------PALSEPGEE 193 SA + + + E P +RD G ++ E+ AL+E Sbjct: 335 SAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYV 394 Query: 194 PQRPSPS 200 P P+ S Sbjct: 395 PDSPALS 401 Score = 34.3 bits (77), Expect = 0.075 Identities = 37/160 (23%), Positives = 58/160 (36%), Gaps = 12/160 (7%) Query: 50 EASPHQRASGEGHHLKSKRPNPCAYTPP-----------SLKAVQRIAESHLQSISNLNE 98 E S H R E + K K + + +PP K V+ +S+L + Sbjct: 210 EVSAHHRTMREDYSDKVKASH-WSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQD 268 Query: 99 NQASEEEDELGELRELGYPREEDEEEEEDDEEEEEEEDSQAEVLKVIRQSAGQKTTCGQG 158 SE + E +EEEEE++EEEEE S+ + + ++ T Sbjct: 269 ISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNS 328 Query: 159 LEGPWERPPPLDESERDGGSEDQVEDPALSEPGEEPQRPS 198 E + + E E E + E+ L P R S Sbjct: 329 EEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDS 368 >gi|21735415 centromere protein B [Homo sapiens] Length = 599 Score = 45.4 bits (106), Expect = 3e-05 Identities = 37/115 (32%), Positives = 53/115 (46%), Gaps = 10/115 (8%) Query: 98 ENQASEEEDELGELRELGYPREEDEEEEEDDEEEEEE-EDSQAEVLKVIRQSAGQKTTCG 156 E + EEE+E GE ELG E +EE + D +EEEEE E+S +E L+ + G G Sbjct: 426 EEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEEEEDEESSSEGLEAEDWAQGVVEAGG 485 Query: 157 Q-GLEGPWERP--PPL------DESERDGGSEDQVEDPALSEPGEEPQRPSPSEP 202 G G E P L ++S+ D ED E+ E ++ + P Sbjct: 486 SFGAYGAQEEAQCPTLHFLEGGEDSDSDSEEEDDEEEDDEDEDDDDDEEDGDEVP 540 Score = 37.0 bits (84), Expect = 0.012 Identities = 33/120 (27%), Positives = 56/120 (46%), Gaps = 13/120 (10%) Query: 94 SNLNENQASEEEDELGELRELGYPREEDEEEEEDDEE--------EEEEEDSQAEVLKVI 145 ++L EEE+E E E G EE+EE EE++EE EEEE + + +V Sbjct: 399 TSLKSEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDE 458 Query: 146 RQSAGQKTTCGQGLEGPWERPPPLDESERDG--GSEDQVEDPALS--EPGEEPQRPSPSE 201 + ++++ +GLE ++ G G++++ + P L E GE+ S E Sbjct: 459 EEEEDEESS-SEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHFLEGGEDSDSDSEEE 517 Score = 30.0 bits (66), Expect = 1.4 Identities = 9/26 (34%), Positives = 21/26 (80%) Query: 119 EEDEEEEEDDEEEEEEEDSQAEVLKV 144 EED+EEE+D++E++++++ + + V Sbjct: 516 EEDDEEEDDEDEDDDDDEEDGDEVPV 541 Score = 29.3 bits (64), Expect = 2.4 Identities = 11/32 (34%), Positives = 24/32 (75%) Query: 120 EDEEEEEDDEEEEEEEDSQAEVLKVIRQSAGQ 151 E+E++EE+D+E+E+++D + + +V S G+ Sbjct: 515 EEEDDEEEDDEDEDDDDDEEDGDEVPVPSFGE 546 >gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens] Length = 770 Score = 45.4 bits (106), Expect = 3e-05 Identities = 34/102 (33%), Positives = 50/102 (49%), Gaps = 7/102 (6%) Query: 88 SHLQSISNLNENQASEEEDELGELRELGYPREEDEEEEEDDEEEEEEEDSQAEVLKVIRQ 147 S +S S + + + EEE+E E E G EE EEEEE++EEEEEE S +E + Q Sbjct: 265 SSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSE--EASEQ 322 Query: 148 SAGQKTTCGQGLEGPWERP-----PPLDESERDGGSEDQVED 184 SA + + + E P +RD G ++ E+ Sbjct: 323 SAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEE 364 Score = 34.3 bits (77), Expect = 0.075 Identities = 37/160 (23%), Positives = 58/160 (36%), Gaps = 12/160 (7%) Query: 50 EASPHQRASGEGHHLKSKRPNPCAYTPP-----------SLKAVQRIAESHLQSISNLNE 98 E S H R E + K K + + +PP K V+ +S+L + Sbjct: 198 EVSAHHRTMREDYSDKVKASH-WSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQD 256 Query: 99 NQASEEEDELGELRELGYPREEDEEEEEDDEEEEEEEDSQAEVLKVIRQSAGQKTTCGQG 158 SE + E +EEEEE++EEEEE S+ + + ++ T Sbjct: 257 ISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNS 316 Query: 159 LEGPWERPPPLDESERDGGSEDQVEDPALSEPGEEPQRPS 198 E + + E E E + E+ L P R S Sbjct: 317 EEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDS 356 Score = 30.0 bits (66), Expect = 1.4 Identities = 21/90 (23%), Positives = 33/90 (36%) Query: 45 SSPEEEASPHQRASGEGHHLKSKRPNPCAYTPPSLKAVQRIAESHLQSISNLNENQASEE 104 S EEE + EG + + E+ QS ++E + SE+ Sbjct: 276 SGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSED 335 Query: 105 EDELGELRELGYPREEDEEEEEDDEEEEEE 134 E+ E L P + + + EE EEE Sbjct: 336 EERENENHLLVVPESRFDRDSGESEEAEEE 365 >gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens] Length = 780 Score = 45.4 bits (106), Expect = 3e-05 Identities = 34/102 (33%), Positives = 50/102 (49%), Gaps = 7/102 (6%) Query: 88 SHLQSISNLNENQASEEEDELGELRELGYPREEDEEEEEDDEEEEEEEDSQAEVLKVIRQ 147 S +S S + + + EEE+E E E G EE EEEEE++EEEEEE S +E + Q Sbjct: 275 SSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSE--EASEQ 332 Query: 148 SAGQKTTCGQGLEGPWERP-----PPLDESERDGGSEDQVED 184 SA + + + E P +RD G ++ E+ Sbjct: 333 SAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEE 374 Score = 34.3 bits (77), Expect = 0.075 Identities = 37/160 (23%), Positives = 58/160 (36%), Gaps = 12/160 (7%) Query: 50 EASPHQRASGEGHHLKSKRPNPCAYTPP-----------SLKAVQRIAESHLQSISNLNE 98 E S H R E + K K + + +PP K V+ +S+L + Sbjct: 208 EVSAHHRTMREDYSDKVKASH-WSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQD 266 Query: 99 NQASEEEDELGELRELGYPREEDEEEEEDDEEEEEEEDSQAEVLKVIRQSAGQKTTCGQG 158 SE + E +EEEEE++EEEEE S+ + + ++ T Sbjct: 267 ISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNS 326 Query: 159 LEGPWERPPPLDESERDGGSEDQVEDPALSEPGEEPQRPS 198 E + + E E E + E+ L P R S Sbjct: 327 EEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDS 366 Score = 30.0 bits (66), Expect = 1.4 Identities = 21/90 (23%), Positives = 33/90 (36%) Query: 45 SSPEEEASPHQRASGEGHHLKSKRPNPCAYTPPSLKAVQRIAESHLQSISNLNENQASEE 104 S EEE + EG + + E+ QS ++E + SE+ Sbjct: 286 SGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSED 345 Query: 105 EDELGELRELGYPREEDEEEEEDDEEEEEE 134 E+ E L P + + + EE EEE Sbjct: 346 EERENENHLLVVPESRFDRDSGESEEAEEE 375 >gi|66792814 retrotransposon gag domain containing 4 [Homo sapiens] Length = 569 Score = 45.1 bits (105), Expect = 4e-05 Identities = 39/156 (25%), Positives = 60/156 (38%), Gaps = 6/156 (3%) Query: 43 EHSSPEEEASPHQRASGEGHHLKSKRPNPCAYTPPSLKAVQRIAESHLQSISNLNENQAS 102 E S EE S + H L SK + E + E + Sbjct: 336 EESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKEE 395 Query: 103 EEEDELGELRELGYPREEDEEEEEDDEEEEEEEDSQAEVLKVIRQSAGQKTTCGQGLEGP 162 EEE+E+ + E R ++EEE E +EE+E+ED + +Q G + T G+ E Sbjct: 396 EEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDPGTEETYGEVEE-- 453 Query: 163 WERPPPLDESERDGGSEDQVEDPALSEPGEEPQRPS 198 PLDE++ D E +P + P+ Sbjct: 454 ----EPLDEAQDDDLDELMEMEPTFVHASSQTSGPT 485 >gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens] Length = 2454 Score = 44.7 bits (104), Expect = 6e-05 Identities = 38/138 (27%), Positives = 65/138 (47%), Gaps = 21/138 (15%) Query: 43 EHSSPEEEASPHQRASGEGHHLKSKRPNPCAYTPPSLKAVQRIAESHLQSISNLNENQAS 102 E S E+E P R++ + +++R S K ++ +Q S+ S Sbjct: 1354 EVSESEDEQRPRTRSAKKAELEENQR---------SYKQKKKRRRIKVQEDSSSENKSNS 1404 Query: 103 EEEDELGELRELGYPREEDEEEEEDDEEEEEEEDSQA-----EVLKVIRQSAGQKTTCGQ 157 EEE+E E EE+EEEEE++EEE+E +DS++ + ++ I + +T Sbjct: 1405 EEEEEEKE-------EEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKLRTETQN 1457 Query: 158 GLEGPWERPPPLDESERD 175 L+ ER + E ER+ Sbjct: 1458 ALKEEEERRKRIAERERE 1475 Score = 35.4 bits (80), Expect = 0.034 Identities = 34/137 (24%), Positives = 58/137 (42%), Gaps = 17/137 (12%) Query: 77 PSLKAVQRIAESHLQSISNLNENQASEEEDELGELRELGYPREEDEEEEEDDEEEEEEED 136 P + +++ +++ + +E+ +S++E E G+ R G EE+ +EE + E D Sbjct: 1229 PENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRT-GKQNEENPGDEEAKNQVNSESD 1287 Query: 137 SQAEVLKVIR---QSAGQKTTCGQGLEGPWERPPPLDESERDGG-----SEDQVEDPALS 188 S +E K R + K T G G ++ P + E G S + ED Sbjct: 1288 SDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQ 1347 Query: 189 EPG--------EEPQRP 197 E G E+ QRP Sbjct: 1348 ESGVSEEVSESEDEQRP 1364 >gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens] Length = 2492 Score = 44.7 bits (104), Expect = 6e-05 Identities = 38/138 (27%), Positives = 65/138 (47%), Gaps = 21/138 (15%) Query: 43 EHSSPEEEASPHQRASGEGHHLKSKRPNPCAYTPPSLKAVQRIAESHLQSISNLNENQAS 102 E S E+E P R++ + +++R S K ++ +Q S+ S Sbjct: 1392 EVSESEDEQRPRTRSAKKAELEENQR---------SYKQKKKRRRIKVQEDSSSENKSNS 1442 Query: 103 EEEDELGELRELGYPREEDEEEEEDDEEEEEEEDSQA-----EVLKVIRQSAGQKTTCGQ 157 EEE+E E EE+EEEEE++EEE+E +DS++ + ++ I + +T Sbjct: 1443 EEEEEEKE-------EEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKLRTETQN 1495 Query: 158 GLEGPWERPPPLDESERD 175 L+ ER + E ER+ Sbjct: 1496 ALKEEEERRKRIAERERE 1513 Score = 35.4 bits (80), Expect = 0.034 Identities = 34/137 (24%), Positives = 58/137 (42%), Gaps = 17/137 (12%) Query: 77 PSLKAVQRIAESHLQSISNLNENQASEEEDELGELRELGYPREEDEEEEEDDEEEEEEED 136 P + +++ +++ + +E+ +S++E E G+ R G EE+ +EE + E D Sbjct: 1267 PENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRT-GKQNEENPGDEEAKNQVNSESD 1325 Query: 137 SQAEVLKVIR---QSAGQKTTCGQGLEGPWERPPPLDESERDGG-----SEDQVEDPALS 188 S +E K R + K T G G ++ P + E G S + ED Sbjct: 1326 SDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQ 1385 Query: 189 EPG--------EEPQRP 197 E G E+ QRP Sbjct: 1386 ESGVSEEVSESEDEQRP 1402 >gi|115529449 upstream binding transcription factor, RNA polymerase I isoform b [Homo sapiens] Length = 727 Score = 44.7 bits (104), Expect = 6e-05 Identities = 32/123 (26%), Positives = 59/123 (47%), Gaps = 22/123 (17%) Query: 52 SPHQRASGEGHHLKSKRPNPCAYTPPSLKAVQRIAESHLQSISNLNENQASEEEDELGE- 110 SP RA+ + ++ +KR + P+ K+ + +S +S + E++ E+EDE E Sbjct: 601 SPQDRAAYK-EYISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEED 659 Query: 111 --------------------LRELGYPREEDEEEEEDDEEEEEEEDSQAEVLKVIRQSAG 150 E G EED+E+E+DDE+++E+ED+++E S+G Sbjct: 660 DENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSG 719 Query: 151 QKT 153 + Sbjct: 720 DSS 722 >gi|115529451 upstream binding transcription factor, RNA polymerase I isoform b [Homo sapiens] Length = 727 Score = 44.7 bits (104), Expect = 6e-05 Identities = 32/123 (26%), Positives = 59/123 (47%), Gaps = 22/123 (17%) Query: 52 SPHQRASGEGHHLKSKRPNPCAYTPPSLKAVQRIAESHLQSISNLNENQASEEEDELGE- 110 SP RA+ + ++ +KR + P+ K+ + +S +S + E++ E+EDE E Sbjct: 601 SPQDRAAYK-EYISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEED 659 Query: 111 --------------------LRELGYPREEDEEEEEDDEEEEEEEDSQAEVLKVIRQSAG 150 E G EED+E+E+DDE+++E+ED+++E S+G Sbjct: 660 DENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSG 719 Query: 151 QKT 153 + Sbjct: 720 DSS 722 >gi|7657671 upstream binding transcription factor, RNA polymerase I isoform a [Homo sapiens] Length = 764 Score = 44.7 bits (104), Expect = 6e-05 Identities = 32/123 (26%), Positives = 59/123 (47%), Gaps = 22/123 (17%) Query: 52 SPHQRASGEGHHLKSKRPNPCAYTPPSLKAVQRIAESHLQSISNLNENQASEEEDELGE- 110 SP RA+ + ++ +KR + P+ K+ + +S +S + E++ E+EDE E Sbjct: 638 SPQDRAAYK-EYISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEED 696 Query: 111 --------------------LRELGYPREEDEEEEEDDEEEEEEEDSQAEVLKVIRQSAG 150 E G EED+E+E+DDE+++E+ED+++E S+G Sbjct: 697 DENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSG 756 Query: 151 QKT 153 + Sbjct: 757 DSS 759 >gi|156142199 euchromatic histone-lysine N-methyltransferase 2 isoform b [Homo sapiens] Length = 1176 Score = 44.3 bits (103), Expect = 7e-05 Identities = 29/96 (30%), Positives = 48/96 (50%), Gaps = 3/96 (3%) Query: 95 NLNENQASEEEDELGELRELGYPREEDEEEEEDDEEEEEEEDSQAEVLKVIRQSAGQKTT 154 +++E S+ + E+ L E EE+EEEEE++EEEEEEE+ + E + QS ++ Sbjct: 278 SVDERVDSDSKSEVEALTEQLSEEEEEEEEEEEEEEEEEEEEEEEEDEESGNQSDRSGSS 337 Query: 155 CGQGLEGPWERPPPLDESERDGGSEDQVEDPALSEP 190 + + W + P + R + E P EP Sbjct: 338 GRRKAKKKWRKDSPWVKPSR---KRRKREPPRAKEP 370 Score = 42.0 bits (97), Expect = 4e-04 Identities = 27/84 (32%), Positives = 42/84 (50%), Gaps = 9/84 (10%) Query: 83 QRIAESHLQSISNLNENQASEEEDELGELRELGYPREEDEEEEEDDEEEEEEEDSQAEVL 142 +R+ + L E + EEE+E E EE+EEEEE++EEEEE+E+S + Sbjct: 281 ERVDSDSKSEVEALTEQLSEEEEEEEEE--------EEEEEEEEEEEEEEEDEESGNQSD 332 Query: 143 KVIRQSAGQKTTCGQGLEGPWERP 166 + S +K + PW +P Sbjct: 333 R-SGSSGRRKAKKKWRKDSPWVKP 355 >gi|156142197 euchromatic histone-lysine N-methyltransferase 2 isoform a [Homo sapiens] Length = 1210 Score = 44.3 bits (103), Expect = 7e-05 Identities = 29/96 (30%), Positives = 48/96 (50%), Gaps = 3/96 (3%) Query: 95 NLNENQASEEEDELGELRELGYPREEDEEEEEDDEEEEEEEDSQAEVLKVIRQSAGQKTT 154 +++E S+ + E+ L E EE+EEEEE++EEEEEEE+ + E + QS ++ Sbjct: 278 SVDERVDSDSKSEVEALTEQLSEEEEEEEEEEEEEEEEEEEEEEEEDEESGNQSDRSGSS 337 Query: 155 CGQGLEGPWERPPPLDESERDGGSEDQVEDPALSEP 190 + + W + P + R + E P EP Sbjct: 338 GRRKAKKKWRKDSPWVKPSR---KRRKREPPRAKEP 370 Score = 42.0 bits (97), Expect = 4e-04 Identities = 27/84 (32%), Positives = 42/84 (50%), Gaps = 9/84 (10%) Query: 83 QRIAESHLQSISNLNENQASEEEDELGELRELGYPREEDEEEEEDDEEEEEEEDSQAEVL 142 +R+ + L E + EEE+E E EE+EEEEE++EEEEE+E+S + Sbjct: 281 ERVDSDSKSEVEALTEQLSEEEEEEEEE--------EEEEEEEEEEEEEEEDEESGNQSD 332 Query: 143 KVIRQSAGQKTTCGQGLEGPWERP 166 + S +K + PW +P Sbjct: 333 R-SGSSGRRKAKKKWRKDSPWVKP 355 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.303 0.126 0.356 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 11,432,036 Number of Sequences: 37866 Number of extensions: 715023 Number of successful extensions: 24155 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 874 Number of HSP's successfully gapped in prelim test: 533 Number of HSP's that attempted gapping in prelim test: 6180 Number of HSP's gapped (non-prelim): 6938 length of query: 204 length of database: 18,247,518 effective HSP length: 97 effective length of query: 107 effective length of database: 14,574,516 effective search space: 1559473212 effective search space used: 1559473212 T: 11 A: 40 X1: 17 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 43 (21.8 bits) S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.