Guide to the Human Genome
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Search of human proteins with 21735492

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|21735492 protein phosphatase 1, regulatory (inhibitor)
subunit 1B isoform 1 [Homo sapiens]
         (204 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|21735492 protein phosphatase 1, regulatory (inhibitor) subuni...   418   e-117
gi|31415880 protein phosphatase 1, regulatory (inhibitor) subuni...   345   1e-95
gi|122937386 protein phosphatase 1, regulatory (inhibitor) subun...    77   1e-14
gi|155030238 protein phosphatase 1, regulatory (inhibitor) subun...    63   2e-10
gi|17975763 myelin transcription factor 1 [Homo sapiens]               51   6e-07
gi|58761548 tau tubulin kinase 1 [Homo sapiens]                        49   2e-06
gi|155030232 proline, glutamic acid and leucine rich protein 1 [...    49   3e-06
gi|100816397 MYST histone acetyltransferase (monocytic leukemia)...    49   4e-06
gi|118600967 shroom family member 4 [Homo sapiens]                     48   7e-06
gi|4504487 histidine rich calcium binding protein precursor [Hom...    47   9e-06
gi|114205399 cyclic nucleotide gated channel beta 1 isoform a [H...    47   1e-05
gi|4506411 Ran GTPase activating protein 1 [Homo sapiens]              47   1e-05
gi|211904182 DDB1 and CUL4 associated factor 8-like 2 [Homo sapi...    46   3e-05
gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof...    46   3e-05
gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isof...    46   3e-05
gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isof...    46   3e-05
gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isof...    46   3e-05
gi|16332360 cell division cycle 2-like 1 (PITSLRE proteins) isof...    46   3e-05
gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isof...    46   3e-05
gi|21735415 centromere protein B [Homo sapiens]                        45   3e-05
gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]     45   3e-05
gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]     45   3e-05
gi|66792814 retrotransposon gag domain containing 4 [Homo sapiens]     45   4e-05
gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]    45   6e-05
gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]    45   6e-05
gi|115529449 upstream binding transcription factor, RNA polymera...    45   6e-05
gi|115529451 upstream binding transcription factor, RNA polymera...    45   6e-05
gi|7657671 upstream binding transcription factor, RNA polymerase...    45   6e-05
gi|156142199 euchromatic histone-lysine N-methyltransferase 2 is...    44   7e-05
gi|156142197 euchromatic histone-lysine N-methyltransferase 2 is...    44   7e-05

>gi|21735492 protein phosphatase 1, regulatory (inhibitor) subunit
           1B isoform 1 [Homo sapiens]
          Length = 204

 Score =  418 bits (1075), Expect = e-117
 Identities = 204/204 (100%), Positives = 204/204 (100%)

Query: 1   MDPKDRKKIQFSVPAPPSQLDPRQVEMIRRRRPTPAMLFRLSEHSSPEEEASPHQRASGE 60
           MDPKDRKKIQFSVPAPPSQLDPRQVEMIRRRRPTPAMLFRLSEHSSPEEEASPHQRASGE
Sbjct: 1   MDPKDRKKIQFSVPAPPSQLDPRQVEMIRRRRPTPAMLFRLSEHSSPEEEASPHQRASGE 60

Query: 61  GHHLKSKRPNPCAYTPPSLKAVQRIAESHLQSISNLNENQASEEEDELGELRELGYPREE 120
           GHHLKSKRPNPCAYTPPSLKAVQRIAESHLQSISNLNENQASEEEDELGELRELGYPREE
Sbjct: 61  GHHLKSKRPNPCAYTPPSLKAVQRIAESHLQSISNLNENQASEEEDELGELRELGYPREE 120

Query: 121 DEEEEEDDEEEEEEEDSQAEVLKVIRQSAGQKTTCGQGLEGPWERPPPLDESERDGGSED 180
           DEEEEEDDEEEEEEEDSQAEVLKVIRQSAGQKTTCGQGLEGPWERPPPLDESERDGGSED
Sbjct: 121 DEEEEEDDEEEEEEEDSQAEVLKVIRQSAGQKTTCGQGLEGPWERPPPLDESERDGGSED 180

Query: 181 QVEDPALSEPGEEPQRPSPSEPGT 204
           QVEDPALSEPGEEPQRPSPSEPGT
Sbjct: 181 QVEDPALSEPGEEPQRPSPSEPGT 204


>gi|31415880 protein phosphatase 1, regulatory (inhibitor) subunit
           1B isoform 2 [Homo sapiens]
          Length = 168

 Score =  345 bits (886), Expect = 1e-95
 Identities = 168/168 (100%), Positives = 168/168 (100%)

Query: 37  MLFRLSEHSSPEEEASPHQRASGEGHHLKSKRPNPCAYTPPSLKAVQRIAESHLQSISNL 96
           MLFRLSEHSSPEEEASPHQRASGEGHHLKSKRPNPCAYTPPSLKAVQRIAESHLQSISNL
Sbjct: 1   MLFRLSEHSSPEEEASPHQRASGEGHHLKSKRPNPCAYTPPSLKAVQRIAESHLQSISNL 60

Query: 97  NENQASEEEDELGELRELGYPREEDEEEEEDDEEEEEEEDSQAEVLKVIRQSAGQKTTCG 156
           NENQASEEEDELGELRELGYPREEDEEEEEDDEEEEEEEDSQAEVLKVIRQSAGQKTTCG
Sbjct: 61  NENQASEEEDELGELRELGYPREEDEEEEEDDEEEEEEEDSQAEVLKVIRQSAGQKTTCG 120

Query: 157 QGLEGPWERPPPLDESERDGGSEDQVEDPALSEPGEEPQRPSPSEPGT 204
           QGLEGPWERPPPLDESERDGGSEDQVEDPALSEPGEEPQRPSPSEPGT
Sbjct: 121 QGLEGPWERPPPLDESERDGGSEDQVEDPALSEPGEEPQRPSPSEPGT 168


>gi|122937386 protein phosphatase 1, regulatory (inhibitor) subunit
           1C [Homo sapiens]
          Length = 109

 Score = 76.6 bits (187), Expect = 1e-14
 Identities = 43/113 (38%), Positives = 58/113 (51%), Gaps = 8/113 (7%)

Query: 1   MDPKDRKKIQFSVPAPPSQLDPRQVEMIRRRRPTPAMLFRLSEHSSPEEEASPHQRASGE 60
           M+P   KKIQF+VP   SQ+ P   E IR+RRPTPA L  L+EH+ PE +        GE
Sbjct: 1   MEPNSPKKIQFAVPVFQSQIAPEAAEQIRKRRPTPASLVILNEHNPPEIDDKRGPNTQGE 60

Query: 61  GHHLKSKRPNPCAYTPPSLKAVQRIAESHLQSISNLNENQASEEEDELGELRE 113
             +   K+     YTPP++K V+         +   NE+   EEE+   E  E
Sbjct: 61  LQNASPKQRKQSVYTPPTIKGVKH--------LKGQNESAFPEEEEGTNEREE 105


>gi|155030238 protein phosphatase 1, regulatory (inhibitor) subunit
           1A [Homo sapiens]
          Length = 171

 Score = 62.8 bits (151), Expect = 2e-10
 Identities = 45/124 (36%), Positives = 58/124 (46%), Gaps = 15/124 (12%)

Query: 7   KKIQFSVPAPPSQLDPRQVEMIRRRRPTPAMLFRLSEHSSPE--EEASPHQRASGEGHHL 64
           +KIQF+VP     LDP   E IRRRRPTPA L   S+ SSPE  E+  P+        HL
Sbjct: 8   RKIQFTVPLLEPHLDPEAAEQIRRRRPTPATLVLTSDQSSPEIDEDRIPNP-------HL 60

Query: 65  KS------KRPNPCAYTPPSLKAVQRIAESHLQSISNLNENQASEEEDELGELRELGYPR 118
           KS      ++        P++K +Q + E HL       E + + E     E R  G P 
Sbjct: 61  KSTLAMSPRQRKKMTRITPTMKELQMMVEHHLGQQQQGEEPEGAAESTGTQESRPPGIPD 120

Query: 119 EEDE 122
            E E
Sbjct: 121 TEVE 124


>gi|17975763 myelin transcription factor 1 [Homo sapiens]
          Length = 1121

 Score = 51.2 bits (121), Expect = 6e-07
 Identities = 31/83 (37%), Positives = 45/83 (54%), Gaps = 4/83 (4%)

Query: 88  SHLQSISNLNENQASEEEDELGELRELGYPREEDEEEEEDDEEEEEEEDSQAEVLKVIRQ 147
           SH +      E +  EEEDE  E  E     EE+EEEEE++EEEEEEE+ +A    + ++
Sbjct: 256 SHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQE 315

Query: 148 ----SAGQKTTCGQGLEGPWERP 166
               ++ QK    +G E P  +P
Sbjct: 316 DTSHTSAQKAPELRGPESPSPKP 338



 Score = 47.0 bits (110), Expect = 1e-05
 Identities = 26/65 (40%), Positives = 36/65 (55%)

Query: 76  PPSLKAVQRIAESHLQSISNLNENQASEEEDELGELRELGYPREEDEEEEEDDEEEEEEE 135
           P SL+       S  + I +  E    EEE+E  E  +     EE+EEEEE++EEEEEEE
Sbjct: 237 PQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEE 296

Query: 136 DSQAE 140
           + + E
Sbjct: 297 EEEEE 301



 Score = 47.0 bits (110), Expect = 1e-05
 Identities = 34/86 (39%), Positives = 46/86 (53%), Gaps = 8/86 (9%)

Query: 93  ISNLNENQASEEEDELGELRELGYPREEDEEEEEDDEEEEEEEDSQAE-----VLKVIRQ 147
           +S+  E++  EEE+E  E  E     EE+EEEEE++EEEEEEE+ + E        VI Q
Sbjct: 255 LSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQ 314

Query: 148 SAGQKTTCGQG--LEGPWERPPPLDE 171
                T+  +   L GP E P P  E
Sbjct: 315 EDTSHTSAQKAPELRGP-ESPSPKPE 339


>gi|58761548 tau tubulin kinase 1 [Homo sapiens]
          Length = 1321

 Score = 49.3 bits (116), Expect = 2e-06
 Identities = 30/75 (40%), Positives = 41/75 (54%), Gaps = 12/75 (16%)

Query: 79  LKAVQRIAESHL------------QSISNLNENQASEEEDELGELRELGYPREEDEEEEE 126
           L  V+R+  SH+            Q  +N  E +  EEEDE  E  +     EE+EEEEE
Sbjct: 702 LNRVRRVGFSHMLLTTPQVPLAPVQPQANGKEEEEEEEEDEEEEEEDEEEEEEEEEEEEE 761

Query: 127 DDEEEEEEEDSQAEV 141
           ++EEEEEEE++ A V
Sbjct: 762 EEEEEEEEEEAAAAV 776


>gi|155030232 proline, glutamic acid and leucine rich protein 1
           [Homo sapiens]
          Length = 1130

 Score = 48.9 bits (115), Expect = 3e-06
 Identities = 43/131 (32%), Positives = 60/131 (45%), Gaps = 13/131 (9%)

Query: 76  PPSLKAVQRIAESHLQSISNLNENQASEEEDELGELRELGYPREEDEEEEEDDEEE--EE 133
           PP+L       E  L  I+  + ++  EEE+E  E  E     EED EEEE+DEEE  EE
Sbjct: 871 PPAL-------EEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEE 923

Query: 134 EEDSQAEVLKVIRQSAGQKTTCGQGLEGPWERPPPLDESE--RDGGSEDQVEDPALSEPG 191
           EE+ + E  +   +  G+     +  E   E    L+E E    G +  +VE+ A   P 
Sbjct: 924 EEEEEEEFEEEFEEEEGELEE--EEEEEDEEEEEELEEVEDLEFGTAGGEVEEGAPPPPT 981

Query: 192 EEPQRPSPSEP 202
             P  P P  P
Sbjct: 982 LPPALPPPESP 992



 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 35/116 (30%), Positives = 50/116 (43%), Gaps = 9/116 (7%)

Query: 87   ESHLQSISNLNENQASEEEDELGELRELGYPREEDEEEEEDDEEEEEEEDSQAEVLKVIR 146
            E + +      E    E E+E GEL E     EE+E+EEE++E EE E+         + 
Sbjct: 918  EEYFEEEEEEEEEFEEEFEEEEGELEE----EEEEEDEEEEEELEEVEDLEFGTAGGEVE 973

Query: 147  QSAGQKTTCGQGLEGPWERPPPLDESERDGGSEDQVEDPALSEPGEEPQRPSPSEP 202
            + A    T    L  P   P    E E + G   +VE     EPG E +R + + P
Sbjct: 974  EGAPPPPTLPPALPPPESPPKVQPEPEPEPGLLLEVE-----EPGTEEERGADTAP 1024



 Score = 41.2 bits (95), Expect = 6e-04
 Identities = 43/149 (28%), Positives = 56/149 (37%), Gaps = 42/149 (28%)

Query: 97   NENQASEEEDELGELRELGYPREEDEEEEEDDEEEEEEEDSQAEVLKV--------IRQS 148
            +E +  EEE+E  E  E  +  EE E EEE++EE+EEEE+   EV  +        + + 
Sbjct: 916  DEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVEDLEFGTAGGEVEEG 975

Query: 149  AGQKTTCGQGLEGPWERPP------------------PLDESER---------------D 175
            A    T    L  P E PP                  P  E ER                
Sbjct: 976  APPPPTLPPALPPP-ESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAPEALPSQ 1034

Query: 176  GGSEDQVEDPALSEPGEEPQRPSPSEPGT 204
            G  E + E PA   P +E     PS P T
Sbjct: 1035 GEVEREGESPAAGPPPQELVEEEPSAPPT 1063



 Score = 28.9 bits (63), Expect = 3.2
 Identities = 40/144 (27%), Positives = 57/144 (39%), Gaps = 33/144 (22%)

Query: 14   PAPPSQLDPRQVEMIRRRRPTPAMLFRLSEHSSPEE-----------EASPHQRASGEGH 62
            PA P    P +V+      P P +L  + E  + EE           EA P Q   GE  
Sbjct: 984  PALPPPESPPKVQP--EPEPEPGLLLEVEEPGTEEERGADTAPTLAPEALPSQ---GE-- 1036

Query: 63   HLKSKRPNPCAYTPPSLKAVQRIAESHLQSISNLNENQASEEEDELGELRELGYPREEDE 122
             ++ +  +P A  PP     Q + E    +   L      EEE E G  +    P    E
Sbjct: 1037 -VEREGESPAAGPPP-----QELVEEEPSAPPTL-----LEEETEDGSDKVQPPPETPAE 1085

Query: 123  EEEEDDEE----EEEEEDSQAEVL 142
            EE E + E    +E+E+D  A +L
Sbjct: 1086 EEMETETEAEALQEKEQDDTAAML 1109


>gi|100816397 MYST histone acetyltransferase (monocytic leukemia) 4
            [Homo sapiens]
          Length = 2073

 Score = 48.5 bits (114), Expect = 4e-06
 Identities = 37/103 (35%), Positives = 50/103 (48%), Gaps = 7/103 (6%)

Query: 40   RLSEHSS---PEEEASPHQRASGEGHHLKSKRPNPCAYTPPSLKAVQRIAESHLQSISNL 96
            RL E +S    EE+     RA+      K +  N   ++P S           L  +S  
Sbjct: 1010 RLMEQASCWEKEEQEILSTRANSRQSPAKVQSKNKYLHSPESRPVTGE--RGQLLELSKE 1067

Query: 97   NENQASEEEDELGELRELGYPREEDEEEEEDDEEEEEEEDSQA 139
            +  +  EEEDE  E  E     EEDEEEEE++EEEEEEE+ Q+
Sbjct: 1068 SSEEEEEEEDEEEEEEE--EEEEEDEEEEEEEEEEEEEENIQS 1108



 Score = 46.6 bits (109), Expect = 1e-05
 Identities = 44/171 (25%), Positives = 73/171 (42%), Gaps = 25/171 (14%)

Query: 39   FRLSEHSSPEEEASPHQRASGEGHHLKSKRPNPCAYTPPSLKAVQRIAESHLQSISNLNE 98
            F+L+ ++ PE    P ++ + E    + K  +    +P  ++  + + E+  +++    E
Sbjct: 1269 FKLNLYTPPETPMEPDEQVTVE----EQKETSEGKTSPSPIRIEEEVKETG-EALLPQEE 1323

Query: 99   NQASEE------EDELGELRE--LGYPREEDEEEEEDDEEEEEEEDSQAEVLKVIRQSAG 150
            N+  E           GE  E  L  P EE+EEEEE++EEEEEEE  + E         G
Sbjct: 1324 NRREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEEEGEEEE-------GGG 1376

Query: 151  QKTTCGQGLEGPWERPPPLDESERDGGSEDQVEDPALSEPGEEPQRPSPSE 201
                   G +   +  P +   + D    D  E     E  EE + PS +E
Sbjct: 1377 NVEKDPDGAKSQEKEEPEISTEKEDSARLDDHE-----EEEEEDEEPSHNE 1422



 Score = 43.9 bits (102), Expect = 1e-04
 Identities = 25/64 (39%), Positives = 39/64 (60%), Gaps = 1/64 (1%)

Query: 78   SLKAVQRIAESHLQSISN-LNENQASEEEDELGELRELGYPREEDEEEEEDDEEEEEEED 136
            S +A  R + + +QS +  L+  ++     E G+L EL     E+EEEEED+EEEEEEE+
Sbjct: 1027 STRANSRQSPAKVQSKNKYLHSPESRPVTGERGQLLELSKESSEEEEEEEDEEEEEEEEE 1086

Query: 137  SQAE 140
             + +
Sbjct: 1087 EEED 1090



 Score = 32.0 bits (71), Expect = 0.37
 Identities = 15/38 (39%), Positives = 22/38 (57%)

Query: 103  EEEDELGELRELGYPREEDEEEEEDDEEEEEEEDSQAE 140
            +EE E+   +E     ++ EEEEE+DEE    ED  A+
Sbjct: 1390 KEEPEISTEKEDSARLDDHEEEEEEDEEPSHNEDHDAD 1427



 Score = 28.9 bits (63), Expect = 3.2
 Identities = 27/103 (26%), Positives = 43/103 (41%), Gaps = 6/103 (5%)

Query: 43   EHSSPEEEASPHQRASGEGHHLKSKRPNPCAYTPPSLKAVQRIAESHLQSISNLNENQAS 102
            E    EEE    +    EG     K P+       S +  +    +  +  + L++++  
Sbjct: 1356 EEEEEEEEEEEEEGEEEEGGGNVEKDPDGAK----SQEKEEPEISTEKEDSARLDDHEEE 1411

Query: 103  EEEDELGELRELGYPREEDEEEEEDDEEEEEE--EDSQAEVLK 143
            EEEDE     E     +ED+   E  E E+EE   +S  EVL+
Sbjct: 1412 EEEDEEPSHNEDHDADDEDDSHMESAEVEKEELPRESFKEVLE 1454



 Score = 28.1 bits (61), Expect = 5.4
 Identities = 15/51 (29%), Positives = 28/51 (54%), Gaps = 1/51 (1%)

Query: 98   ENQASEEEDELGELRELGYPREEDEEE-EEDDEEEEEEEDSQAEVLKVIRQ 147
            E + S E+++   L +     EEDEE    +D + ++E+DS  E  +V ++
Sbjct: 1392 EPEISTEKEDSARLDDHEEEEEEDEEPSHNEDHDADDEDDSHMESAEVEKE 1442


>gi|118600967 shroom family member 4 [Homo sapiens]
          Length = 1493

 Score = 47.8 bits (112), Expect = 7e-06
 Identities = 33/114 (28%), Positives = 48/114 (42%), Gaps = 13/114 (11%)

Query: 76   PPSLKAVQRIAESHLQSISNLNENQASEEEDELGELRELGYPREEDEEEEEDDEEEEEEE 135
            PP+ +  +    +  Q      + Q  EEE             EE+EEEEE++EEEEEE 
Sbjct: 1106 PPNWEKYRLFRAAQQQKQQQQQQKQQEEEE-------------EEEEEEEEEEEEEEEEA 1152

Query: 136  DSQAEVLKVIRQSAGQKTTCGQGLEGPWERPPPLDESERDGGSEDQVEDPALSE 189
            + + E L     S+    +C    E   E+P PL     +G  +     PA  E
Sbjct: 1153 EEEEEELPPQYFSSETSGSCALNPEEVLEQPQPLSFGHLEGSRQGSQSVPAEQE 1206


>gi|4504487 histidine rich calcium binding protein precursor [Homo
           sapiens]
          Length = 699

 Score = 47.4 bits (111), Expect = 9e-06
 Identities = 38/112 (33%), Positives = 55/112 (49%), Gaps = 11/112 (9%)

Query: 103 EEEDELGELRELGYPREEDEEEEEDDEEEEEEEDSQ-----AEV-LKVIRQSAGQKTTCG 156
           ++EDE  E    G    ++EEEEED EEEEEEED +     AEV   +    + ++    
Sbjct: 515 DQEDEEDEEEGHGLSLNQEEEEEEDKEEEEEEEDEERREERAEVGAPLSPDHSEEEEEEE 574

Query: 157 QGLEGPWER----PPPLDESERDGGSEDQVEDPALSEPGEEPQRPSPSEPGT 204
           +GLE    R    P PLD  E  GG+  + E    + P ++ Q     +PG+
Sbjct: 575 EGLEEDEPRFTIIPNPLDRREEAGGASSEEESGEDTGP-QDAQEYGNYQPGS 625



 Score = 42.0 bits (97), Expect = 4e-04
 Identities = 40/146 (27%), Positives = 56/146 (38%), Gaps = 29/146 (19%)

Query: 44  HSSPEEEASPHQRASGEGHHLKSKRPNPCAYTPPSLKAVQRIAESHLQSISNLNENQASE 103
           H S + E S   R     HHL S R                   SH     + +E  +SE
Sbjct: 137 HGSEDTEDSAEHR-----HHLPSHR-------------------SHSHQDEDEDEVVSSE 172

Query: 104 EEDELGELRELGYPREEDEEEEEDDEEEEEEEDS-----QAEVLKVIRQSAGQKTTCGQG 158
               +      G+  E+DE EEE++EEEEEEE S     QA   +       +  + G  
Sbjct: 173 HHHHILRHGHRGHDGEDDEGEEEEEEEEEEEEASTEYGHQAHRHRGHGSEEDEDVSDGHH 232

Query: 159 LEGPWERPPPLDESERDGGSEDQVED 184
             GP  R    +E + D   +D  +D
Sbjct: 233 HHGPSHRHQGHEEDDDDDDDDDDDDD 258



 Score = 30.8 bits (68), Expect = 0.83
 Identities = 21/107 (19%), Positives = 47/107 (43%), Gaps = 9/107 (8%)

Query: 97  NENQASEEEDELGELRELGYP------REEDEEEEEDDEEEEEEEDSQAEVLKVIRQSAG 150
           +    SEE++++ +      P       EED+++++DD+++++++D   E      +  G
Sbjct: 216 HRGHGSEEDEDVSDGHHHHGPSHRHQGHEEDDDDDDDDDDDDDDDDVSIEYRHQAHRHQG 275

Query: 151 QKTTCGQGL-EGPWERPPPLDESERDGGSEDQVEDPALSEPGEEPQR 196
                 + + +G   R P      R    +D  +D   +E G +  R
Sbjct: 276 HGIEEDEDVSDGHHHRDP--SHRHRSHEEDDNDDDDVSTEYGHQAHR 320


>gi|114205399 cyclic nucleotide gated channel beta 1 isoform a [Homo
           sapiens]
          Length = 1251

 Score = 47.0 bits (110), Expect = 1e-05
 Identities = 33/107 (30%), Positives = 53/107 (49%), Gaps = 12/107 (11%)

Query: 101 ASEEEDELGELRELGYPREEDEEEEEDDEEEEEEEDSQAEVLKVIRQS-------AGQKT 153
           A EEE++  E       R E+E+E+E++EEEEEEE+ + EV +V+  S        GQ  
Sbjct: 332 AYEEENKAVEKMPRELSRIEEEKEDEEEEEEEEEEEEEEEVTEVLLDSCVVSQVGVGQSE 391

Query: 154 TCGQGLEGP-----WERPPPLDESERDGGSEDQVEDPALSEPGEEPQ 195
             G   +       WE      + E +  ++++ E+ A  E  +EPQ
Sbjct: 392 EDGTRPQSTSDQKLWEEVGEEAKKEAEEKAKEEAEEVAEEEAEKEPQ 438



 Score = 30.4 bits (67), Expect = 1.1
 Identities = 20/66 (30%), Positives = 33/66 (50%), Gaps = 8/66 (12%)

Query: 75  TPPSLKAVQRIAESHLQSISNLNENQASEEEDELGELRELGYPREEDEEEEEDDEEEEEE 134
           T P   + Q++ E   +      E +A EE +E+ E        EE E+E +D  E +EE
Sbjct: 395 TRPQSTSDQKLWEEVGEEAKKEAEEKAKEEAEEVAE--------EEAEKEPQDWAETKEE 446

Query: 135 EDSQAE 140
            +++AE
Sbjct: 447 PEAEAE 452


>gi|4506411 Ran GTPase activating protein 1 [Homo sapiens]
          Length = 587

 Score = 47.0 bits (110), Expect = 1e-05
 Identities = 32/112 (28%), Positives = 50/112 (44%), Gaps = 29/112 (25%)

Query: 93  ISNLNENQASEEEDELGELRELGYPREEDEEEEEDDEEEEEEEDSQAEVLKVIRQSAGQK 152
           +++L++++  EEE+E  E  E     EE++EEEE++EEEEEEE+ Q              
Sbjct: 354 LASLSDDEDEEEEEEGEEEEEEAEEEEEEDEEEEEEEEEEEEEEPQQR------------ 401

Query: 153 TTCGQGLEGPWERPPPLDESERDGGSEDQVEDPALSEPGEEPQRPSPSEPGT 204
              GQG              E+      ++ DP   EP      P P++  T
Sbjct: 402 ---GQG--------------EKSATPSRKILDPNTGEPAPVLSSPPPADVST 436


>gi|211904182 DDB1 and CUL4 associated factor 8-like 2 [Homo
           sapiens]
          Length = 631

 Score = 45.8 bits (107), Expect = 3e-05
 Identities = 23/41 (56%), Positives = 30/41 (73%), Gaps = 2/41 (4%)

Query: 98  ENQASEEEDELGELRELGYPREEDEEEEEDDEEEEEEEDSQ 138
           E    EEEDE  E++E G   EE+EEEEE++EEEEEEE+ +
Sbjct: 109 EETEREEEDE--EIQEEGGEEEEEEEEEEEEEEEEEEEEEE 147



 Score = 44.7 bits (104), Expect = 6e-05
 Identities = 22/41 (53%), Positives = 30/41 (73%), Gaps = 2/41 (4%)

Query: 98  ENQASEEEDELGELRELGYPREEDEEEEEDDEEEEEEEDSQ 138
           E +  EE++E+ E  E G   EE+EEEEE++EEEEEEE+ Q
Sbjct: 110 ETEREEEDEEIQE--EGGEEEEEEEEEEEEEEEEEEEEEEQ 148



 Score = 29.3 bits (64), Expect = 2.4
 Identities = 30/96 (31%), Positives = 40/96 (41%), Gaps = 22/96 (22%)

Query: 92  SISNLNENQASEEED-ELGELRELG-----------YPR--EEDEEEEEDD--------E 129
           S  N + +Q S  ED EL  L +             YP   EE+ E EE+D        E
Sbjct: 67  STENRSSDQESASEDIELESLEDFEHFLMSGESLFHYPLVGEEETEREEEDEEIQEEGGE 126

Query: 130 EEEEEEDSQAEVLKVIRQSAGQKTTCGQGLEGPWER 165
           EEEEEE+ + E  +   +   Q     QG  G  E+
Sbjct: 127 EEEEEEEEEEEEEEEEEEEEEQPRAGPQGSGGNHEQ 162



 Score = 27.3 bits (59), Expect = 9.2
 Identities = 23/91 (25%), Positives = 37/91 (40%), Gaps = 12/91 (13%)

Query: 112 RELGYPREEDEEEEEDDEEEEEEEDSQAEVLKVIRQSAGQKTTCGQGL-------EGPWE 164
           R+ G+P +   E    D +E   ED + E L+            G+ L       E   E
Sbjct: 58  RDGGFPNDASTENRSSD-QESASEDIELESLEDFEHF----LMSGESLFHYPLVGEEETE 112

Query: 165 RPPPLDESERDGGSEDQVEDPALSEPGEEPQ 195
           R    +E + +GG E++ E+    E  EE +
Sbjct: 113 REEEDEEIQEEGGEEEEEEEEEEEEEEEEEE 143


>gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           9 [Homo sapiens]
          Length = 771

 Score = 45.8 bits (107), Expect = 3e-05
 Identities = 40/127 (31%), Positives = 58/127 (45%), Gaps = 16/127 (12%)

Query: 88  SHLQSISNLNENQASEEEDELGELRELGYPREEDEEEEEDDEEEEEEEDSQAEVLKVIRQ 147
           S  +S S  + + + EEE+E  E  E G   EE EEEEE++EEEEEE  S +E  +   Q
Sbjct: 266 SSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSE--EASEQ 323

Query: 148 SAGQKTTCGQGLEGPWERP-----PPLDESERDGGSEDQVED---------PALSEPGEE 193
           SA + +      +   E        P    +RD G  ++ E+          AL+E    
Sbjct: 324 SAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYV 383

Query: 194 PQRPSPS 200
           P  P+ S
Sbjct: 384 PDSPALS 390



 Score = 34.3 bits (77), Expect = 0.075
 Identities = 37/160 (23%), Positives = 58/160 (36%), Gaps = 12/160 (7%)

Query: 50  EASPHQRASGEGHHLKSKRPNPCAYTPP-----------SLKAVQRIAESHLQSISNLNE 98
           E S H R   E +  K K  +  + +PP             K V+         +S+L +
Sbjct: 199 EVSAHHRTMREDYSDKVKASH-WSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQD 257

Query: 99  NQASEEEDELGELRELGYPREEDEEEEEDDEEEEEEEDSQAEVLKVIRQSAGQKTTCGQG 158
              SE +    E          +EEEEE++EEEEE   S+    +   +   ++ T    
Sbjct: 258 ISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNS 317

Query: 159 LEGPWERPPPLDESERDGGSEDQVEDPALSEPGEEPQRPS 198
            E   +    + E E     E + E+  L  P     R S
Sbjct: 318 EEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDS 357


>gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           8 [Homo sapiens]
          Length = 780

 Score = 45.8 bits (107), Expect = 3e-05
 Identities = 40/127 (31%), Positives = 58/127 (45%), Gaps = 16/127 (12%)

Query: 88  SHLQSISNLNENQASEEEDELGELRELGYPREEDEEEEEDDEEEEEEEDSQAEVLKVIRQ 147
           S  +S S  + + + EEE+E  E  E G   EE EEEEE++EEEEEE  S +E  +   Q
Sbjct: 275 SSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSE--EASEQ 332

Query: 148 SAGQKTTCGQGLEGPWERP-----PPLDESERDGGSEDQVED---------PALSEPGEE 193
           SA + +      +   E        P    +RD G  ++ E+          AL+E    
Sbjct: 333 SAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYV 392

Query: 194 PQRPSPS 200
           P  P+ S
Sbjct: 393 PDSPALS 399



 Score = 34.3 bits (77), Expect = 0.075
 Identities = 37/160 (23%), Positives = 58/160 (36%), Gaps = 12/160 (7%)

Query: 50  EASPHQRASGEGHHLKSKRPNPCAYTPP-----------SLKAVQRIAESHLQSISNLNE 98
           E S H R   E +  K K  +  + +PP             K V+         +S+L +
Sbjct: 208 EVSAHHRTMREDYSDKVKASH-WSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQD 266

Query: 99  NQASEEEDELGELRELGYPREEDEEEEEDDEEEEEEEDSQAEVLKVIRQSAGQKTTCGQG 158
              SE +    E          +EEEEE++EEEEE   S+    +   +   ++ T    
Sbjct: 267 ISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNS 326

Query: 159 LEGPWERPPPLDESERDGGSEDQVEDPALSEPGEEPQRPS 198
            E   +    + E E     E + E+  L  P     R S
Sbjct: 327 EEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDS 366


>gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           5 [Homo sapiens]
          Length = 748

 Score = 45.8 bits (107), Expect = 3e-05
 Identities = 40/127 (31%), Positives = 58/127 (45%), Gaps = 16/127 (12%)

Query: 88  SHLQSISNLNENQASEEEDELGELRELGYPREEDEEEEEDDEEEEEEEDSQAEVLKVIRQ 147
           S  +S S  + + + EEE+E  E  E G   EE EEEEE++EEEEEE  S +E  +   Q
Sbjct: 243 SSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSE--EASEQ 300

Query: 148 SAGQKTTCGQGLEGPWERP-----PPLDESERDGGSEDQVED---------PALSEPGEE 193
           SA + +      +   E        P    +RD G  ++ E+          AL+E    
Sbjct: 301 SAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYV 360

Query: 194 PQRPSPS 200
           P  P+ S
Sbjct: 361 PDSPALS 367



 Score = 34.3 bits (77), Expect = 0.075
 Identities = 37/160 (23%), Positives = 58/160 (36%), Gaps = 12/160 (7%)

Query: 50  EASPHQRASGEGHHLKSKRPNPCAYTPP-----------SLKAVQRIAESHLQSISNLNE 98
           E S H R   E +  K K  +  + +PP             K V+         +S+L +
Sbjct: 176 EVSAHHRTMREDYSDKVKASH-WSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQD 234

Query: 99  NQASEEEDELGELRELGYPREEDEEEEEDDEEEEEEEDSQAEVLKVIRQSAGQKTTCGQG 158
              SE +    E          +EEEEE++EEEEE   S+    +   +   ++ T    
Sbjct: 235 ISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNS 294

Query: 159 LEGPWERPPPLDESERDGGSEDQVEDPALSEPGEEPQRPS 198
            E   +    + E E     E + E+  L  P     R S
Sbjct: 295 EEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDS 334


>gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           4 [Homo sapiens]
          Length = 737

 Score = 45.8 bits (107), Expect = 3e-05
 Identities = 40/127 (31%), Positives = 58/127 (45%), Gaps = 16/127 (12%)

Query: 88  SHLQSISNLNENQASEEEDELGELRELGYPREEDEEEEEDDEEEEEEEDSQAEVLKVIRQ 147
           S  +S S  + + + EEE+E  E  E G   EE EEEEE++EEEEEE  S +E  +   Q
Sbjct: 232 SSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSE--EASEQ 289

Query: 148 SAGQKTTCGQGLEGPWERP-----PPLDESERDGGSEDQVED---------PALSEPGEE 193
           SA + +      +   E        P    +RD G  ++ E+          AL+E    
Sbjct: 290 SAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYV 349

Query: 194 PQRPSPS 200
           P  P+ S
Sbjct: 350 PDSPALS 356



 Score = 34.3 bits (77), Expect = 0.075
 Identities = 37/160 (23%), Positives = 58/160 (36%), Gaps = 12/160 (7%)

Query: 50  EASPHQRASGEGHHLKSKRPNPCAYTPP-----------SLKAVQRIAESHLQSISNLNE 98
           E S H R   E +  K K  +  + +PP             K V+         +S+L +
Sbjct: 165 EVSAHHRTMREDYSDKVKASH-WSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQD 223

Query: 99  NQASEEEDELGELRELGYPREEDEEEEEDDEEEEEEEDSQAEVLKVIRQSAGQKTTCGQG 158
              SE +    E          +EEEEE++EEEEE   S+    +   +   ++ T    
Sbjct: 224 ISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNS 283

Query: 159 LEGPWERPPPLDESERDGGSEDQVEDPALSEPGEEPQRPS 198
            E   +    + E E     E + E+  L  P     R S
Sbjct: 284 EEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDS 323


>gi|16332360 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           3 [Homo sapiens]
          Length = 526

 Score = 45.8 bits (107), Expect = 3e-05
 Identities = 40/127 (31%), Positives = 58/127 (45%), Gaps = 16/127 (12%)

Query: 88  SHLQSISNLNENQASEEEDELGELRELGYPREEDEEEEEDDEEEEEEEDSQAEVLKVIRQ 147
           S  +S S  + + + EEE+E  E  E G   EE EEEEE++EEEEEE  S +E  +   Q
Sbjct: 21  SSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSE--EASEQ 78

Query: 148 SAGQKTTCGQGLEGPWERP-----PPLDESERDGGSEDQVED---------PALSEPGEE 193
           SA + +      +   E        P    +RD G  ++ E+          AL+E    
Sbjct: 79  SAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYV 138

Query: 194 PQRPSPS 200
           P  P+ S
Sbjct: 139 PDSPALS 145



 Score = 33.9 bits (76), Expect = 0.098
 Identities = 26/106 (24%), Positives = 42/106 (39%)

Query: 93  ISNLNENQASEEEDELGELRELGYPREEDEEEEEDDEEEEEEEDSQAEVLKVIRQSAGQK 152
           +S+L +   SE +    E          +EEEEE++EEEEE   S+    +   +   ++
Sbjct: 7   LSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEE 66

Query: 153 TTCGQGLEGPWERPPPLDESERDGGSEDQVEDPALSEPGEEPQRPS 198
            T     E   +    + E E     E + E+  L  P     R S
Sbjct: 67  ETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDS 112



 Score = 33.9 bits (76), Expect = 0.098
 Identities = 23/60 (38%), Positives = 31/60 (51%), Gaps = 10/60 (16%)

Query: 88  SHLQSISNLNENQASEEEDELGELRELGYPREEDEEEEEDD---------EEEEEEEDSQ 138
           S LQ IS+ +E + S  E    E        EE+EEEEE++         EEEEEEE+ +
Sbjct: 8   SDLQDISD-SERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEE 66


>gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           2 [Homo sapiens]
          Length = 782

 Score = 45.8 bits (107), Expect = 3e-05
 Identities = 40/127 (31%), Positives = 58/127 (45%), Gaps = 16/127 (12%)

Query: 88  SHLQSISNLNENQASEEEDELGELRELGYPREEDEEEEEDDEEEEEEEDSQAEVLKVIRQ 147
           S  +S S  + + + EEE+E  E  E G   EE EEEEE++EEEEEE  S +E  +   Q
Sbjct: 277 SSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSE--EASEQ 334

Query: 148 SAGQKTTCGQGLEGPWERP-----PPLDESERDGGSEDQVED---------PALSEPGEE 193
           SA + +      +   E        P    +RD G  ++ E+          AL+E    
Sbjct: 335 SAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYV 394

Query: 194 PQRPSPS 200
           P  P+ S
Sbjct: 395 PDSPALS 401



 Score = 34.3 bits (77), Expect = 0.075
 Identities = 37/160 (23%), Positives = 58/160 (36%), Gaps = 12/160 (7%)

Query: 50  EASPHQRASGEGHHLKSKRPNPCAYTPP-----------SLKAVQRIAESHLQSISNLNE 98
           E S H R   E +  K K  +  + +PP             K V+         +S+L +
Sbjct: 210 EVSAHHRTMREDYSDKVKASH-WSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQD 268

Query: 99  NQASEEEDELGELRELGYPREEDEEEEEDDEEEEEEEDSQAEVLKVIRQSAGQKTTCGQG 158
              SE +    E          +EEEEE++EEEEE   S+    +   +   ++ T    
Sbjct: 269 ISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNS 328

Query: 159 LEGPWERPPPLDESERDGGSEDQVEDPALSEPGEEPQRPS 198
            E   +    + E E     E + E+  L  P     R S
Sbjct: 329 EEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDS 368


>gi|21735415 centromere protein B [Homo sapiens]
          Length = 599

 Score = 45.4 bits (106), Expect = 3e-05
 Identities = 37/115 (32%), Positives = 53/115 (46%), Gaps = 10/115 (8%)

Query: 98  ENQASEEEDELGELRELGYPREEDEEEEEDDEEEEEE-EDSQAEVLKVIRQSAGQKTTCG 156
           E +  EEE+E GE  ELG   E +EE + D +EEEEE E+S +E L+    + G     G
Sbjct: 426 EEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEEEEDEESSSEGLEAEDWAQGVVEAGG 485

Query: 157 Q-GLEGPWERP--PPL------DESERDGGSEDQVEDPALSEPGEEPQRPSPSEP 202
             G  G  E    P L      ++S+ D   ED  E+    E  ++ +      P
Sbjct: 486 SFGAYGAQEEAQCPTLHFLEGGEDSDSDSEEEDDEEEDDEDEDDDDDEEDGDEVP 540



 Score = 37.0 bits (84), Expect = 0.012
 Identities = 33/120 (27%), Positives = 56/120 (46%), Gaps = 13/120 (10%)

Query: 94  SNLNENQASEEEDELGELRELGYPREEDEEEEEDDEE--------EEEEEDSQAEVLKVI 145
           ++L      EEE+E  E  E G   EE+EE EE++EE        EEEE + + +V    
Sbjct: 399 TSLKSEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDE 458

Query: 146 RQSAGQKTTCGQGLEGPWERPPPLDESERDG--GSEDQVEDPALS--EPGEEPQRPSPSE 201
            +   ++++  +GLE        ++     G  G++++ + P L   E GE+    S  E
Sbjct: 459 EEEEDEESS-SEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHFLEGGEDSDSDSEEE 517



 Score = 30.0 bits (66), Expect = 1.4
 Identities = 9/26 (34%), Positives = 21/26 (80%)

Query: 119 EEDEEEEEDDEEEEEEEDSQAEVLKV 144
           EED+EEE+D++E++++++   + + V
Sbjct: 516 EEDDEEEDDEDEDDDDDEEDGDEVPV 541



 Score = 29.3 bits (64), Expect = 2.4
 Identities = 11/32 (34%), Positives = 24/32 (75%)

Query: 120 EDEEEEEDDEEEEEEEDSQAEVLKVIRQSAGQ 151
           E+E++EE+D+E+E+++D + +  +V   S G+
Sbjct: 515 EEEDDEEEDDEDEDDDDDEEDGDEVPVPSFGE 546


>gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]
          Length = 770

 Score = 45.4 bits (106), Expect = 3e-05
 Identities = 34/102 (33%), Positives = 50/102 (49%), Gaps = 7/102 (6%)

Query: 88  SHLQSISNLNENQASEEEDELGELRELGYPREEDEEEEEDDEEEEEEEDSQAEVLKVIRQ 147
           S  +S S  + + + EEE+E  E  E G   EE EEEEE++EEEEEE  S +E  +   Q
Sbjct: 265 SSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSE--EASEQ 322

Query: 148 SAGQKTTCGQGLEGPWERP-----PPLDESERDGGSEDQVED 184
           SA + +      +   E        P    +RD G  ++ E+
Sbjct: 323 SAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEE 364



 Score = 34.3 bits (77), Expect = 0.075
 Identities = 37/160 (23%), Positives = 58/160 (36%), Gaps = 12/160 (7%)

Query: 50  EASPHQRASGEGHHLKSKRPNPCAYTPP-----------SLKAVQRIAESHLQSISNLNE 98
           E S H R   E +  K K  +  + +PP             K V+         +S+L +
Sbjct: 198 EVSAHHRTMREDYSDKVKASH-WSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQD 256

Query: 99  NQASEEEDELGELRELGYPREEDEEEEEDDEEEEEEEDSQAEVLKVIRQSAGQKTTCGQG 158
              SE +    E          +EEEEE++EEEEE   S+    +   +   ++ T    
Sbjct: 257 ISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNS 316

Query: 159 LEGPWERPPPLDESERDGGSEDQVEDPALSEPGEEPQRPS 198
            E   +    + E E     E + E+  L  P     R S
Sbjct: 317 EEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDS 356



 Score = 30.0 bits (66), Expect = 1.4
 Identities = 21/90 (23%), Positives = 33/90 (36%)

Query: 45  SSPEEEASPHQRASGEGHHLKSKRPNPCAYTPPSLKAVQRIAESHLQSISNLNENQASEE 104
           S  EEE    +    EG   +              +      E+  QS   ++E + SE+
Sbjct: 276 SGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSED 335

Query: 105 EDELGELRELGYPREEDEEEEEDDEEEEEE 134
           E+   E   L  P    + +  + EE EEE
Sbjct: 336 EERENENHLLVVPESRFDRDSGESEEAEEE 365


>gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]
          Length = 780

 Score = 45.4 bits (106), Expect = 3e-05
 Identities = 34/102 (33%), Positives = 50/102 (49%), Gaps = 7/102 (6%)

Query: 88  SHLQSISNLNENQASEEEDELGELRELGYPREEDEEEEEDDEEEEEEEDSQAEVLKVIRQ 147
           S  +S S  + + + EEE+E  E  E G   EE EEEEE++EEEEEE  S +E  +   Q
Sbjct: 275 SSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSE--EASEQ 332

Query: 148 SAGQKTTCGQGLEGPWERP-----PPLDESERDGGSEDQVED 184
           SA + +      +   E        P    +RD G  ++ E+
Sbjct: 333 SAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEE 374



 Score = 34.3 bits (77), Expect = 0.075
 Identities = 37/160 (23%), Positives = 58/160 (36%), Gaps = 12/160 (7%)

Query: 50  EASPHQRASGEGHHLKSKRPNPCAYTPP-----------SLKAVQRIAESHLQSISNLNE 98
           E S H R   E +  K K  +  + +PP             K V+         +S+L +
Sbjct: 208 EVSAHHRTMREDYSDKVKASH-WSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQD 266

Query: 99  NQASEEEDELGELRELGYPREEDEEEEEDDEEEEEEEDSQAEVLKVIRQSAGQKTTCGQG 158
              SE +    E          +EEEEE++EEEEE   S+    +   +   ++ T    
Sbjct: 267 ISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNS 326

Query: 159 LEGPWERPPPLDESERDGGSEDQVEDPALSEPGEEPQRPS 198
            E   +    + E E     E + E+  L  P     R S
Sbjct: 327 EEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDS 366



 Score = 30.0 bits (66), Expect = 1.4
 Identities = 21/90 (23%), Positives = 33/90 (36%)

Query: 45  SSPEEEASPHQRASGEGHHLKSKRPNPCAYTPPSLKAVQRIAESHLQSISNLNENQASEE 104
           S  EEE    +    EG   +              +      E+  QS   ++E + SE+
Sbjct: 286 SGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSED 345

Query: 105 EDELGELRELGYPREEDEEEEEDDEEEEEE 134
           E+   E   L  P    + +  + EE EEE
Sbjct: 346 EERENENHLLVVPESRFDRDSGESEEAEEE 375


>gi|66792814 retrotransposon gag domain containing 4 [Homo sapiens]
          Length = 569

 Score = 45.1 bits (105), Expect = 4e-05
 Identities = 39/156 (25%), Positives = 60/156 (38%), Gaps = 6/156 (3%)

Query: 43  EHSSPEEEASPHQRASGEGHHLKSKRPNPCAYTPPSLKAVQRIAESHLQSISNLNENQAS 102
           E S  EE  S  +      H L SK               +   E   +      E +  
Sbjct: 336 EESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKEE 395

Query: 103 EEEDELGELRELGYPREEDEEEEEDDEEEEEEEDSQAEVLKVIRQSAGQKTTCGQGLEGP 162
           EEE+E+ +  E    R ++EEE E  +EE+E+ED   +     +Q  G + T G+  E  
Sbjct: 396 EEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDPGTEETYGEVEE-- 453

Query: 163 WERPPPLDESERDGGSEDQVEDPALSEPGEEPQRPS 198
                PLDE++ D   E    +P       +   P+
Sbjct: 454 ----EPLDEAQDDDLDELMEMEPTFVHASSQTSGPT 485


>gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]
          Length = 2454

 Score = 44.7 bits (104), Expect = 6e-05
 Identities = 38/138 (27%), Positives = 65/138 (47%), Gaps = 21/138 (15%)

Query: 43   EHSSPEEEASPHQRASGEGHHLKSKRPNPCAYTPPSLKAVQRIAESHLQSISNLNENQAS 102
            E S  E+E  P  R++ +    +++R         S K  ++     +Q  S+      S
Sbjct: 1354 EVSESEDEQRPRTRSAKKAELEENQR---------SYKQKKKRRRIKVQEDSSSENKSNS 1404

Query: 103  EEEDELGELRELGYPREEDEEEEEDDEEEEEEEDSQA-----EVLKVIRQSAGQKTTCGQ 157
            EEE+E  E        EE+EEEEE++EEE+E +DS++     + ++ I +    +T    
Sbjct: 1405 EEEEEEKE-------EEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKLRTETQN 1457

Query: 158  GLEGPWERPPPLDESERD 175
             L+   ER   + E ER+
Sbjct: 1458 ALKEEEERRKRIAERERE 1475



 Score = 35.4 bits (80), Expect = 0.034
 Identities = 34/137 (24%), Positives = 58/137 (42%), Gaps = 17/137 (12%)

Query: 77   PSLKAVQRIAESHLQSISNLNENQASEEEDELGELRELGYPREEDEEEEEDDEEEEEEED 136
            P  +  +++    +++  + +E+ +S++E E G+ R  G   EE+  +EE   +   E D
Sbjct: 1229 PENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRT-GKQNEENPGDEEAKNQVNSESD 1287

Query: 137  SQAEVLKVIR---QSAGQKTTCGQGLEGPWERPPPLDESERDGG-----SEDQVEDPALS 188
            S +E  K  R   +    K T   G  G  ++  P +  E  G      S +  ED    
Sbjct: 1288 SDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQ 1347

Query: 189  EPG--------EEPQRP 197
            E G        E+ QRP
Sbjct: 1348 ESGVSEEVSESEDEQRP 1364


>gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]
          Length = 2492

 Score = 44.7 bits (104), Expect = 6e-05
 Identities = 38/138 (27%), Positives = 65/138 (47%), Gaps = 21/138 (15%)

Query: 43   EHSSPEEEASPHQRASGEGHHLKSKRPNPCAYTPPSLKAVQRIAESHLQSISNLNENQAS 102
            E S  E+E  P  R++ +    +++R         S K  ++     +Q  S+      S
Sbjct: 1392 EVSESEDEQRPRTRSAKKAELEENQR---------SYKQKKKRRRIKVQEDSSSENKSNS 1442

Query: 103  EEEDELGELRELGYPREEDEEEEEDDEEEEEEEDSQA-----EVLKVIRQSAGQKTTCGQ 157
            EEE+E  E        EE+EEEEE++EEE+E +DS++     + ++ I +    +T    
Sbjct: 1443 EEEEEEKE-------EEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKLRTETQN 1495

Query: 158  GLEGPWERPPPLDESERD 175
             L+   ER   + E ER+
Sbjct: 1496 ALKEEEERRKRIAERERE 1513



 Score = 35.4 bits (80), Expect = 0.034
 Identities = 34/137 (24%), Positives = 58/137 (42%), Gaps = 17/137 (12%)

Query: 77   PSLKAVQRIAESHLQSISNLNENQASEEEDELGELRELGYPREEDEEEEEDDEEEEEEED 136
            P  +  +++    +++  + +E+ +S++E E G+ R  G   EE+  +EE   +   E D
Sbjct: 1267 PENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRT-GKQNEENPGDEEAKNQVNSESD 1325

Query: 137  SQAEVLKVIR---QSAGQKTTCGQGLEGPWERPPPLDESERDGG-----SEDQVEDPALS 188
            S +E  K  R   +    K T   G  G  ++  P +  E  G      S +  ED    
Sbjct: 1326 SDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQ 1385

Query: 189  EPG--------EEPQRP 197
            E G        E+ QRP
Sbjct: 1386 ESGVSEEVSESEDEQRP 1402


>gi|115529449 upstream binding transcription factor, RNA polymerase
           I isoform b [Homo sapiens]
          Length = 727

 Score = 44.7 bits (104), Expect = 6e-05
 Identities = 32/123 (26%), Positives = 59/123 (47%), Gaps = 22/123 (17%)

Query: 52  SPHQRASGEGHHLKSKRPNPCAYTPPSLKAVQRIAESHLQSISNLNENQASEEEDELGE- 110
           SP  RA+ +  ++ +KR +      P+ K+ +   +S  +S  +  E++  E+EDE  E 
Sbjct: 601 SPQDRAAYK-EYISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEED 659

Query: 111 --------------------LRELGYPREEDEEEEEDDEEEEEEEDSQAEVLKVIRQSAG 150
                                 E G   EED+E+E+DDE+++E+ED+++E       S+G
Sbjct: 660 DENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSG 719

Query: 151 QKT 153
             +
Sbjct: 720 DSS 722


>gi|115529451 upstream binding transcription factor, RNA polymerase
           I isoform b [Homo sapiens]
          Length = 727

 Score = 44.7 bits (104), Expect = 6e-05
 Identities = 32/123 (26%), Positives = 59/123 (47%), Gaps = 22/123 (17%)

Query: 52  SPHQRASGEGHHLKSKRPNPCAYTPPSLKAVQRIAESHLQSISNLNENQASEEEDELGE- 110
           SP  RA+ +  ++ +KR +      P+ K+ +   +S  +S  +  E++  E+EDE  E 
Sbjct: 601 SPQDRAAYK-EYISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEED 659

Query: 111 --------------------LRELGYPREEDEEEEEDDEEEEEEEDSQAEVLKVIRQSAG 150
                                 E G   EED+E+E+DDE+++E+ED+++E       S+G
Sbjct: 660 DENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSG 719

Query: 151 QKT 153
             +
Sbjct: 720 DSS 722


>gi|7657671 upstream binding transcription factor, RNA polymerase I
           isoform a [Homo sapiens]
          Length = 764

 Score = 44.7 bits (104), Expect = 6e-05
 Identities = 32/123 (26%), Positives = 59/123 (47%), Gaps = 22/123 (17%)

Query: 52  SPHQRASGEGHHLKSKRPNPCAYTPPSLKAVQRIAESHLQSISNLNENQASEEEDELGE- 110
           SP  RA+ +  ++ +KR +      P+ K+ +   +S  +S  +  E++  E+EDE  E 
Sbjct: 638 SPQDRAAYK-EYISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEED 696

Query: 111 --------------------LRELGYPREEDEEEEEDDEEEEEEEDSQAEVLKVIRQSAG 150
                                 E G   EED+E+E+DDE+++E+ED+++E       S+G
Sbjct: 697 DENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSG 756

Query: 151 QKT 153
             +
Sbjct: 757 DSS 759


>gi|156142199 euchromatic histone-lysine N-methyltransferase 2
           isoform b [Homo sapiens]
          Length = 1176

 Score = 44.3 bits (103), Expect = 7e-05
 Identities = 29/96 (30%), Positives = 48/96 (50%), Gaps = 3/96 (3%)

Query: 95  NLNENQASEEEDELGELRELGYPREEDEEEEEDDEEEEEEEDSQAEVLKVIRQSAGQKTT 154
           +++E   S+ + E+  L E     EE+EEEEE++EEEEEEE+ + E  +   QS    ++
Sbjct: 278 SVDERVDSDSKSEVEALTEQLSEEEEEEEEEEEEEEEEEEEEEEEEDEESGNQSDRSGSS 337

Query: 155 CGQGLEGPWERPPPLDESERDGGSEDQVEDPALSEP 190
             +  +  W +  P  +  R      + E P   EP
Sbjct: 338 GRRKAKKKWRKDSPWVKPSR---KRRKREPPRAKEP 370



 Score = 42.0 bits (97), Expect = 4e-04
 Identities = 27/84 (32%), Positives = 42/84 (50%), Gaps = 9/84 (10%)

Query: 83  QRIAESHLQSISNLNENQASEEEDELGELRELGYPREEDEEEEEDDEEEEEEEDSQAEVL 142
           +R+       +  L E  + EEE+E  E        EE+EEEEE++EEEEE+E+S  +  
Sbjct: 281 ERVDSDSKSEVEALTEQLSEEEEEEEEE--------EEEEEEEEEEEEEEEDEESGNQSD 332

Query: 143 KVIRQSAGQKTTCGQGLEGPWERP 166
           +    S  +K       + PW +P
Sbjct: 333 R-SGSSGRRKAKKKWRKDSPWVKP 355


>gi|156142197 euchromatic histone-lysine N-methyltransferase 2
           isoform a [Homo sapiens]
          Length = 1210

 Score = 44.3 bits (103), Expect = 7e-05
 Identities = 29/96 (30%), Positives = 48/96 (50%), Gaps = 3/96 (3%)

Query: 95  NLNENQASEEEDELGELRELGYPREEDEEEEEDDEEEEEEEDSQAEVLKVIRQSAGQKTT 154
           +++E   S+ + E+  L E     EE+EEEEE++EEEEEEE+ + E  +   QS    ++
Sbjct: 278 SVDERVDSDSKSEVEALTEQLSEEEEEEEEEEEEEEEEEEEEEEEEDEESGNQSDRSGSS 337

Query: 155 CGQGLEGPWERPPPLDESERDGGSEDQVEDPALSEP 190
             +  +  W +  P  +  R      + E P   EP
Sbjct: 338 GRRKAKKKWRKDSPWVKPSR---KRRKREPPRAKEP 370



 Score = 42.0 bits (97), Expect = 4e-04
 Identities = 27/84 (32%), Positives = 42/84 (50%), Gaps = 9/84 (10%)

Query: 83  QRIAESHLQSISNLNENQASEEEDELGELRELGYPREEDEEEEEDDEEEEEEEDSQAEVL 142
           +R+       +  L E  + EEE+E  E        EE+EEEEE++EEEEE+E+S  +  
Sbjct: 281 ERVDSDSKSEVEALTEQLSEEEEEEEEE--------EEEEEEEEEEEEEEEDEESGNQSD 332

Query: 143 KVIRQSAGQKTTCGQGLEGPWERP 166
           +    S  +K       + PW +P
Sbjct: 333 R-SGSSGRRKAKKKWRKDSPWVKP 355


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.303    0.126    0.356 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,432,036
Number of Sequences: 37866
Number of extensions: 715023
Number of successful extensions: 24155
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 874
Number of HSP's successfully gapped in prelim test: 533
Number of HSP's that attempted gapping in prelim test: 6180
Number of HSP's gapped (non-prelim): 6938
length of query: 204
length of database: 18,247,518
effective HSP length: 97
effective length of query: 107
effective length of database: 14,574,516
effective search space: 1559473212
effective search space used: 1559473212
T: 11
A: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.8 bits)
S2: 59 (27.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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