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Search of human proteins with 21735415
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|21735415 centromere protein B [Homo sapiens]
(599 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|21735415 centromere protein B [Homo sapiens] 1196 0.0
gi|13569924 hypothetical protein LOC81789 [Homo sapiens] 202 5e-52
gi|22219477 tigger transposable element derived 4 [Homo sapiens] 184 2e-46
gi|23312394 tigger transposable element derived 3 [Homo sapiens] 145 1e-34
gi|23312392 tigger transposable element derived 2 [Homo sapiens] 136 5e-32
gi|22547224 jerky homolog-like [Homo sapiens] 117 3e-26
gi|144922631 tigger transposable element derived 5 [Homo sapiens] 114 3e-25
gi|22325392 tigger transposable element derived 7 [Homo sapiens] 112 1e-24
gi|117938293 jerky isoform a [Homo sapiens] 108 1e-23
gi|117938295 jerky isoform b [Homo sapiens] 108 1e-23
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 103 5e-22
gi|22209001 hypothetical protein LOC200765 [Homo sapiens] 95 2e-19
gi|55956788 nucleolin [Homo sapiens] 87 3e-17
gi|4759128 solute carrier family 24 (sodium/potassium/calcium ex... 84 3e-16
gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 82 1e-15
gi|13540523 nucleosomal binding protein 1 [Homo sapiens] 79 1e-14
gi|13569879 acidic (leucine-rich) nuclear phosphoprotein 32 fami... 76 1e-13
gi|210147569 acidic (leucine-rich) nuclear phosphoprotein 32 fam... 76 1e-13
gi|210147571 acidic (leucine-rich) nuclear phosphoprotein 32 fam... 76 1e-13
gi|28274705 family with sequence similarity 9, member A [Homo sa... 75 2e-13
gi|17975763 myelin transcription factor 1 [Homo sapiens] 74 3e-13
gi|5454088 acidic (leucine-rich) nuclear phosphoprotein 32 famil... 74 3e-13
gi|115529449 upstream binding transcription factor, RNA polymera... 72 1e-12
gi|115529451 upstream binding transcription factor, RNA polymera... 72 1e-12
gi|7657671 upstream binding transcription factor, RNA polymerase... 72 1e-12
gi|42476169 Paf1, RNA polymerase II associated factor, homolog [... 72 1e-12
gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens] 72 2e-12
gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens] 72 2e-12
gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof... 72 2e-12
gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isof... 72 2e-12
>gi|21735415 centromere protein B [Homo sapiens]
Length = 599
Score = 1196 bits (3093), Expect = 0.0
Identities = 599/599 (100%), Positives = 599/599 (100%)
Query: 1 MGPKRRQLTFREKSRIIQEVEENPDLRKGEIARRFNIPPSTLSTILKNKRAILASERKYG 60
MGPKRRQLTFREKSRIIQEVEENPDLRKGEIARRFNIPPSTLSTILKNKRAILASERKYG
Sbjct: 1 MGPKRRQLTFREKSRIIQEVEENPDLRKGEIARRFNIPPSTLSTILKNKRAILASERKYG 60
Query: 61 VASTCRKTNKLSPYDKLEGLLIAWFQQIRAAGLPVKGIILKEKALRIAEELGMDDFTASN 120
VASTCRKTNKLSPYDKLEGLLIAWFQQIRAAGLPVKGIILKEKALRIAEELGMDDFTASN
Sbjct: 61 VASTCRKTNKLSPYDKLEGLLIAWFQQIRAAGLPVKGIILKEKALRIAEELGMDDFTASN 120
Query: 121 GWLDRFRRRHGVVSCSGVARARARNAAPRTPAAPASPAAVPSEGSGGSTTGWRAREEQPP 180
GWLDRFRRRHGVVSCSGVARARARNAAPRTPAAPASPAAVPSEGSGGSTTGWRAREEQPP
Sbjct: 121 GWLDRFRRRHGVVSCSGVARARARNAAPRTPAAPASPAAVPSEGSGGSTTGWRAREEQPP 180
Query: 181 SVAEGYASQDVFSATETSLWYDFLPDQAAGLCGGDGRPRQATQRLSVLLCANADGSEKLP 240
SVAEGYASQDVFSATETSLWYDFLPDQAAGLCGGDGRPRQATQRLSVLLCANADGSEKLP
Sbjct: 181 SVAEGYASQDVFSATETSLWYDFLPDQAAGLCGGDGRPRQATQRLSVLLCANADGSEKLP 240
Query: 241 PLVAGKSAKPRAGQAGLPCDYTANSKGGVTTQALAKYLKALDTRMAAESRRVLLLAGRLA 300
PLVAGKSAKPRAGQAGLPCDYTANSKGGVTTQALAKYLKALDTRMAAESRRVLLLAGRLA
Sbjct: 241 PLVAGKSAKPRAGQAGLPCDYTANSKGGVTTQALAKYLKALDTRMAAESRRVLLLAGRLA 300
Query: 301 AQSLDTSGLRHVQLAFFPPGTVHPLERGVVQQVKGHYRQAMLLKAMAALEGQDPSGLQLG 360
AQSLDTSGLRHVQLAFFPPGTVHPLERGVVQQVKGHYRQAMLLKAMAALEGQDPSGLQLG
Sbjct: 301 AQSLDTSGLRHVQLAFFPPGTVHPLERGVVQQVKGHYRQAMLLKAMAALEGQDPSGLQLG 360
Query: 361 LTEALHFVAAAWQAVEPSDIAACFREAGFGGGPNATITTSLKSEGEEEEEEEEEEEEEEG 420
LTEALHFVAAAWQAVEPSDIAACFREAGFGGGPNATITTSLKSEGEEEEEEEEEEEEEEG
Sbjct: 361 LTEALHFVAAAWQAVEPSDIAACFREAGFGGGPNATITTSLKSEGEEEEEEEEEEEEEEG 420
Query: 421 EGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEEEEDEESSSEGLEAEDWAQGV 480
EGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEEEEDEESSSEGLEAEDWAQGV
Sbjct: 421 EGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEEEEDEESSSEGLEAEDWAQGV 480
Query: 481 VEAGGSFGAYGAQEEAQCPTLHFLEGGEDSDSDSEEEDDEEEDDEDEDDDDDEEDGDEVP 540
VEAGGSFGAYGAQEEAQCPTLHFLEGGEDSDSDSEEEDDEEEDDEDEDDDDDEEDGDEVP
Sbjct: 481 VEAGGSFGAYGAQEEAQCPTLHFLEGGEDSDSDSEEEDDEEEDDEDEDDDDDEEDGDEVP 540
Query: 541 VPSFGEAMAYFAMVKRYLTSFPIDDRVQSHILHLEHDLVHVTRKNHARQAGVRGLGHQS 599
VPSFGEAMAYFAMVKRYLTSFPIDDRVQSHILHLEHDLVHVTRKNHARQAGVRGLGHQS
Sbjct: 541 VPSFGEAMAYFAMVKRYLTSFPIDDRVQSHILHLEHDLVHVTRKNHARQAGVRGLGHQS 599
>gi|13569924 hypothetical protein LOC81789 [Homo sapiens]
Length = 521
Score = 202 bits (515), Expect = 5e-52
Identities = 128/392 (32%), Positives = 202/392 (51%), Gaps = 30/392 (7%)
Query: 4 KRRQLTFREKSRIIQEVEENPDLRKGEIARRFNIPPSTLSTILKNKRAILASERKYGVAS 63
KRRQ + EK +++ V+ RKG++A+ F I PSTLST LK++ R+ V
Sbjct: 8 KRRQFSLEEKMKVVGAVDSGK--RKGDVAKEFGITPSTLSTFLKDRTKFEEKVREASVGP 65
Query: 64 TCRKTNKLSPYDKLEGLLIAWFQQIRAAGLPVKGIILKEKALRIAEELGMDDFTASNGWL 123
RK + + YD ++ + AWFQ+I A + V G ++++KAL +A LG D+F AS GWL
Sbjct: 66 Q-RKRMRSALYDDIDKAVFAWFQEIHAKNILVTGSVIRKKALNLANMLGYDNFQASVGWL 124
Query: 124 DRFRRRHGVVSCSGVARARARNAAPRTPAAPASPAAVPSEGSG-GSTTGWRAREEQPPSV 182
+RFR RHG+ +A R + R G G W A E +
Sbjct: 125 NRFRDRHGIA-----LKAVCREDSDRL-----------MNGLGIDKINEWHAGEII--KL 166
Query: 183 AEGYASQDVFSATETSLWYDFLPDQAAGLCGGDGRP-RQATQRLSVLLCANADGSEKLPP 241
Y+ D+F+A ET +++ LP G R ++A QRL+ L C NA G+EK+ P
Sbjct: 167 IADYSPDDIFNADETGVFFQLLPQHTLAAKGDHCRGGKKAKQRLTALFCCNASGTEKMRP 226
Query: 242 LVAGKSAKPRA--GQAGLPCDYTANSKGGVTTQALAKYLKALDTRMAAESRRVLLLAGRL 299
L+ G+SA P LPCDY AN +T ++L +D RM RR+LLL
Sbjct: 227 LIVGRSASPHCLKNIHSLPCDYRANQWAWMTRDLFNEWLMQVDARMKRAERRILLLIDNC 286
Query: 300 AAQSLDTSGLRHVQLAFFP---PGTVHPLERGVVQQVKGHYRQAMLLKAMAALEGQDPSG 356
+A ++ L +Q+ + P + PL G++ +K Y+ +L + + L +
Sbjct: 287 SAHNM-LPHLERIQVGYLPSNCTAVLQPLNLGIIHTMKVLYQSHLLKQILLKLNSSEDQE 345
Query: 357 LQLGLTEALHFVAAAWQAVEPSDIAACFREAG 388
++ + +A+ +AAAW +V+PS + C+++AG
Sbjct: 346 -EVDIKQAIDMIAAAWWSVKPSTVVKCWQKAG 376
>gi|22219477 tigger transposable element derived 4 [Homo sapiens]
Length = 512
Score = 184 bits (467), Expect = 2e-46
Identities = 154/579 (26%), Positives = 248/579 (42%), Gaps = 97/579 (16%)
Query: 4 KRRQLTFREKSRIIQEVEENPDLRKGEIARRFNIPPSTLSTILKNKRAILASERKYGVAS 63
K++ L+ EK II VE +K EIA + I ++LS+I+KNK +L +
Sbjct: 17 KKKSLSIEEKIDIINAVESGK--KKAEIAAEYGIKKNSLSSIMKNKDKVLEAFESLRFDP 74
Query: 64 TCRKTNKLSPYDKLEGLLIAWFQQIRAAGLPVKGIILKEKALRIAEELGMDDFTASNGWL 123
RK + + Y LE L+ W++ + +PV G +L+ KA A++LG +DF SNGWL
Sbjct: 75 K-RKRLRTAFYTDLEEALMRWYRIAQCLNVPVNGPMLRLKANDFAQKLGHNDFKCSNGWL 133
Query: 124 DRFRRRHGVVSCSGVARARARNAAPRTPAAPASPAAVPSEGSGGSTTGWRAREEQPPSVA 183
DRF+ R+G+V A P VP + S T W + P
Sbjct: 134 DRFKSRYGLVF----------------RAQPVEATGVPVDPS----TVWY--QNVLPYYL 171
Query: 184 EGYASQDVFSATETSLWYDFLPDQAAGLCGGD-GRPRQATQRLSVLLCANADGSEKLPPL 242
Y ++VF+ ET L Y LP G + R+++++ N DGSEKLP L
Sbjct: 172 NDYHPKNVFNIKETGLLYRMLPTNTFAFKGETCSVGKLCKDRITLVVGTNMDGSEKLPLL 231
Query: 243 VAGKSAKPRA--GQAGLPCDYTANSKGGVTTQALAKYLKALDTRMAAESRRVLLLAGRLA 300
V GK P G LP Y AN +T+ ++++ LD A+ RRV++
Sbjct: 232 VIGKKRTPHCFKGLKSLPVCYEANRMAWMTSDVFEQWMRKLDEEFQAQQRRVVIFVESFP 291
Query: 301 AQSLDTSGLRHVQLAFFPP---GTVHPLERGVVQQVKGHYRQAMLLKAMAALEGQDPSGL 357
A + L+ ++LAFFP +++GV++ +K YR ++ K ++++EG
Sbjct: 292 AHP-EVKNLKSIELAFFPSCLSSKCIAMKQGVIKSLKIKYRHCLIKKFLSSVEGSKE--F 348
Query: 358 QLGLTEALHFVAAAWQAVEPSDIAACFREAGFGGGPNATITTSLKSEGEEEEEEEEEEEE 417
L +A+ + W+AV P I + EAGF + ++ E
Sbjct: 349 TFSLLDAVDTLHLCWRAVTPETIVKSYEEAGF----------------------KSQKGE 386
Query: 418 EEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEEEEDEESSSEGLEAEDWA 477
+ E++ + + G G E E +EE +D D E E +
Sbjct: 387 SDITNAEKDTGLDLVADALGAGVEFPEGLSIEEYAALDDDLETCEAAPNG---------- 436
Query: 478 QGVVEAGGSFGAYGAQEEAQCPTLHFLEGGEDSDSDSEEEDDEEEDDEDEDDDDDEEDGD 537
DS E + DE +++DDD G
Sbjct: 437 -------------------------------DSICTKESKSDETGFYTSDEEDDDGSPGT 465
Query: 538 EVPVPSFGEAMAYFAMVKRYLTSFPIDDRVQSHILHLEH 576
E+P+PS EA+ +K++L S ++D +Q+ + LE+
Sbjct: 466 ELPLPSKSEAITALDTLKKFLRSQDMNDGLQNSLADLEN 504
>gi|23312394 tigger transposable element derived 3 [Homo sapiens]
Length = 471
Score = 145 bits (365), Expect = 1e-34
Identities = 136/455 (29%), Positives = 202/455 (44%), Gaps = 58/455 (12%)
Query: 4 KRRQLTFREKSRIIQEVEENPDLRKGEIARRFNIPPSTLSTILKNKRAILASERKYGVAS 63
K L+ EK ++++ ++E+ + + E+ARRF + +S I KNK +LA G A+
Sbjct: 8 KLHALSLAEKIQVLELLDESK-MSQSEVARRFQVSQPQISRICKNKEKLLADWCS-GTAN 65
Query: 64 TCRKTNKLSPYDKLEGLLIAWFQQIRAAGLPVKGIILKEKALRIAEELGMDDFTASNGWL 123
RK + S Y ++ L+ W+ RA V G +L KA +A+ +G DF S GWL
Sbjct: 66 RERKRKRESKYSGIDEALLCWYHIARAKAWDVTGPMLLHKAKELADIMG-QDFVPSIGWL 124
Query: 124 DRFRRRHGVVSCSGVARARARNAAPRTPAAPASPAAVPSEGSGGSTTGWRAREEQPPSVA 183
R++RR+ V R AP+ P P G + Q P
Sbjct: 125 VRWKRRNNV------------GFGARHVLAPSFPPEPPPPG--------LTSQAQLPLSL 164
Query: 184 EGYASQDVFSATETSLWYDFLPDQAAGLCGGDGRPRQATQRLSVLLCANADGSEKLPPLV 243
+ ++ +DVF E L Y +P G G A ++ VLLCAN+ G+EK L+
Sbjct: 165 KDFSPEDVFGCAELPLLYRAVP-------GSFG----ACDQVQVLLCANSRGTEKRRVLL 213
Query: 244 AGKSAKPRA----GQAGLPCDYTANSKGGVTTQALAKYLKALDTRMAAESRRV-LLLAGR 298
G A PR LP Y + G+ ++L D M + R+V LLLA R
Sbjct: 214 GGLQAAPRCFFGIRSEALPASYHPDL--GI---PWLEWLAQFDRDMGQQGRQVALLLAAR 268
Query: 299 LAAQSLDTSGLRHVQ-LAFFPPGTVHPLERGVVQQVKGHYRQAMLLKAMAALEGQD---- 353
+ + GL HV+ L T PL VV+ K HYR +L K A +D
Sbjct: 269 VVEELAGLPGLYHVKLLPLAASSTTPPLPSSVVRAFKAHYRHRLLGKLAAIQSERDGTSL 328
Query: 354 -PSGLQLGLTEALHFVAAAWQAVEPSDIAACFREAGFGGG---PNATITTSLKS-----E 404
+G + + +ALH +AAW V P I + F + G G P++ T+ +
Sbjct: 329 AEAGAGITVLDALHVASAAWAKVPPQLIFSSFIQEGLAPGKTPPSSHKTSEMPPVPGGLS 388
Query: 405 GEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEG 439
EE + E EE G +EE G E+E+ EG
Sbjct: 389 LEEFSRFVDLEGEEPRSGVCKEEIGTEDEKGDREG 423
>gi|23312392 tigger transposable element derived 2 [Homo sapiens]
Length = 525
Score = 136 bits (343), Expect = 5e-32
Identities = 142/534 (26%), Positives = 237/534 (44%), Gaps = 101/534 (18%)
Query: 4 KRRQLTFREKSRIIQEVEENPDLRKGEIARRFNIPPSTLSTILKNKRAIL----ASERKY 59
KR LT ++K II+++EE +K + + I ST+ I KNK I+ +S+
Sbjct: 6 KRVVLTIKDKLDIIKKLEEGISFKKLSVV--YGIGESTVRDIKKNKERIINYANSSDPTS 63
Query: 60 GVASTCRKTNKLSPYDKLEGLLIAWFQQIRAAGLPVKGIILKEKALRIAEELGMD-DFTA 118
GV+ RK+ K S Y++L+ ++I WF Q + G+PV G I ++A + LGM+ DF A
Sbjct: 64 GVSK--RKSMKSSTYEELDRVMIEWFNQQKTDGIPVSGTICAKQAKFFFDALGMEGDFNA 121
Query: 119 SNGWLDRFRRRHGVVSCSGV-ARARARNAAPRTPAAPASPAAVPSEGSGGSTTGWRAREE 177
S+GWL RF++RHG+ +G + + A R GS + +E
Sbjct: 122 SSGWLTRFKQRHGIPKAAGKGTKLKGDETAAREFC--------------GSFQEFVEKEN 167
Query: 178 QPPSVAEGYASQDVFSATETSLWYDFLP--------DQAAGLCGGDGRPRQATQRLSVLL 229
P + ++ A +T L++ LP DQ+ C R + +R+ ++
Sbjct: 168 LQP--------EQIYGADQTGLFWKCLPSRTLTLETDQSTSGC------RSSRERIIIMC 213
Query: 230 CANADGSEKLPPLVAGKSAKPRAGQ----AGLPCDYTANS----KGGVTTQALAKYL--- 278
CANA G KL V GK+ KPRA + + LP Y + + V Q KY
Sbjct: 214 CANATGLHKLNLCVVGKAKKPRAFKGTDLSNLPVTYYSQKGAWIEQSVFRQWFEKYFVPQ 273
Query: 279 --KALDTRMAAESRRVLLLAGRLAA--QSLDTSGLRHVQLAFFPPGT---VHPLERGVVQ 331
K L ++ E + VLLL A + + +S + + + PP + P+ +GV+
Sbjct: 274 VQKHLKSKGLLE-KAVLLLDFPPARPNEEMLSSDDGRIIVKYLPPNVTSLIQPMSQGVLA 332
Query: 332 QVKGHYRQAMLLKAMAALEGQDPSGLQLGLT--EALHFVAAAWQAVEPSDIAACFREAGF 389
VK +YR +L K M EG DP LT +A++ V+ AW V+ S I +++
Sbjct: 333 TVKRYYRAGLLQKYMD--EGNDPKIFWKNLTVLDAIYEVSRAWNMVKSSTITKAWKKLFP 390
Query: 390 GGGPN------------ATITTSLKSEGEEEEEEEEEEEE---------------EEGEG 422
G N A + T L++ E E + E ++ +
Sbjct: 391 GNEENSGMNIDEGAILAANLATVLQNTEECEHVDIENIDQWFDSRSSDSSCQVLTDSESA 450
Query: 423 EEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEE-----EEEDEESSSEGL 471
E++ + E++ EL E+ + + ++ E E++D+ S+ L
Sbjct: 451 EDQTKAAEQKPSSKSRKTELNPEKHISHKAALEWTENLLDYLEQQDDMLLSDKL 504
>gi|22547224 jerky homolog-like [Homo sapiens]
Length = 524
Score = 117 bits (293), Expect = 3e-26
Identities = 127/491 (25%), Positives = 211/491 (42%), Gaps = 59/491 (12%)
Query: 4 KRRQLTFREKSRIIQEVEENPDLRKGEIARRFNIPPSTLSTILKNKRAIL--ASERKYGV 61
KR LT ++K II+++E+ + ++A + I +T+ I KNK I+ AS
Sbjct: 6 KRVVLTIKDKLDIIKKLEDGGSSK--QLAVIYGIGETTVRDIRKNKEKIITYASSSDSTS 63
Query: 62 ASTCRKTNKLSPYDKLEGLLIAWFQQIRAAGLPVKGIILKEKALRIAEELGMD-DFTASN 120
RK+ K S Y++L+ ++ WF Q RA G P+ G I ++A LGMD DF S
Sbjct: 64 LLAKRKSMKPSMYEELDRAMLEWFNQQRAKGNPISGPICAKRAEFFFYALGMDGDFNPSA 123
Query: 121 GWLDRFRRRHGVVSCSGVARARARNAAPRTPAAPASPAAVPSEGSGGSTTGWRAREEQPP 180
GWL RF++RH + R R AV E + + RE P
Sbjct: 124 GWLTRFKQRHSI-----------REINIRNERLNGDETAV--EDFCNNFRDFIERENLQP 170
Query: 181 SVAEGYASQDVFSATETSLWYDFLPDQAA---GLCGGDGRPRQATQRLSVLLCANADGSE 237
+ +++A ET L++ LP + + G C G + +R++++ CANA G
Sbjct: 171 --------EQIYNADETGLFWKCLPSRISVIKGKCTVPGH-KSIEERVTIMCCANATGLH 221
Query: 238 KLPPLVAGKSAKPRAGQA----GLPCDYTANSKGGVTTQALAKYLKALDTRMAAE----- 288
KL V GK+ KPR+ ++ LP Y + + ++ + E
Sbjct: 222 KLKLCVVGKAKKPRSFKSTDTLNLPVSYFSQKGAWMDLSIFRQWFDKIFVPQVREYLRSK 281
Query: 289 ---SRRVLLL--AGRLAAQSLDTSGLRHVQLAFFPPGT---VHPLERGVVQQVKGHYRQA 340
+ VLLL + +++ S + + PP + P ++GV+ +K +YR
Sbjct: 282 GLQEKAVLLLDNSPTHPNENVLRSDDGQIFAKYLPPNVASLIQPSDQGVIATMKRNYRAG 341
Query: 341 MLLKAMAALEGQDPSGL--QLGLTEALHFVAAAWQAVEPSDIAACFREAGFGGGPNATIT 398
+L + EG D +L L +AL+ +A AW V+P I+ +++ P
Sbjct: 342 LLQNNLE--EGNDLKSFWKKLTLLDALYEIAMAWNLVKPVTISRAWKKI----LPMVEEK 395
Query: 399 TSLKSEGEEEEEEEEEEEEEEGEGEE----EEEEGEEEEEEGGEGEELGEEEEVEEEGDV 454
SL + E+ + +G E E E E + G E+ + E+
Sbjct: 396 ESLDFDVEDISVATVAAILQHTKGLENVTTENLEKWLEVDSTEPGYEVLTDSEIIRRAQG 455
Query: 455 DSDEEEEEDEE 465
+DE E +EE
Sbjct: 456 QADESSENEEE 466
>gi|144922631 tigger transposable element derived 5 [Homo sapiens]
Length = 593
Score = 114 bits (285), Expect = 3e-25
Identities = 112/433 (25%), Positives = 189/433 (43%), Gaps = 61/433 (14%)
Query: 5 RRQLTFREKSRIIQEVEENPDLRKGEIARRFNIPPSTLSTILKNKRAIL-ASERKYGVAS 63
R+ + ++K + I+ V+ R+ + R F +P TL LK++ + E+ G
Sbjct: 4 RKAYSIKDKLQAIERVKGGE--RQASVCRDFGVPGGTLRGWLKDEPKLRWFLEQLGGEVG 61
Query: 64 TCRKTNKLSPYDKLEGLLIAWFQQIRAAGLPVKGIILKEKALRIAEELGMDD--FTASNG 121
T RK +L+ ++++ + AWF +R G+P+ G +++ +A A ++ + F AS+G
Sbjct: 62 TQRKKMRLANEEEIDRAVYAWFLALRQHGVPLSGPLIQAQAEAFARQIYGPECTFKASHG 121
Query: 122 WLDRFRRRHGVVSCSGVARARARNAAPRTPAAPASPAAV-PSEGSGGSTTGWRAREEQPP 180
W R+++RHG+ S R P AP P P+ SG RA PP
Sbjct: 122 WFWRWQKRHGISS----QRFYGEAGPPAPSPAPGPPVKEEPALPSGAGPLPDRAPAPPPP 177
Query: 181 SVAEGYASQDVFSATETSLWYDFLPDQAAGL------CGGDGRPRQATQRLSVLLCANAD 234
+ GY + ++SA+ T L++ LP+QAA GG GR R R++VLL AN
Sbjct: 178 AEG-GYGDEQIYSASVTGLYWKLLPEQAAPPGAGDPGAGGCGR-RWRGDRVTVLLAANLT 235
Query: 235 GSEKLPPLVAGKSAKPRA----GQAGLPCDYTANSKGGVTTQALAKY--------LKALD 282
GS KL PLV G+ P + Q P Y + ++ L + +K
Sbjct: 236 GSHKLKPLVIGRLPDPPSLRHHNQDKFPASYRYSPDAWLSRPLLRGWFFEEFVPGVKRYL 295
Query: 283 TRMAAESRRVLLL--------AGRLAAQSLDTSGLR-----------------HVQLAFF 317
R + + VLL+ A + A + + +R V++ F
Sbjct: 296 RRSCLQQKAVLLVAHPPCPSPAASMPALDSEDAPVRCRPEPLGPPEELQTPDGAVRVLFL 355
Query: 318 PPGTVH-----PLERGVVQQVKGHYRQAMLLKAMAALEGQDPSGLQ-LGLTEALHFVAAA 371
G+ PLE+GVV K Y++ +L A++ G ++ L + L+ +
Sbjct: 356 SKGSSRAHIPAPLEQGVVAAFKQLYKRELLRLAVSCASGSPLDFMRSFMLKDMLYLAGLS 415
Query: 372 WQAVEPSDIAACF 384
W V+ I C+
Sbjct: 416 WDLVQAGSIERCW 428
>gi|22325392 tigger transposable element derived 7 [Homo sapiens]
Length = 549
Score = 112 bits (279), Expect = 1e-24
Identities = 131/528 (24%), Positives = 215/528 (40%), Gaps = 80/528 (15%)
Query: 4 KRRQLTFREKSRIIQEVEENPDLRKGEIARRFNIPPSTLSTILKNKRAILASERKYG--- 60
K L EK +++ +E L+ + F I ST I KNK+ IL K
Sbjct: 6 KYTTLNLEEKMKVLSRIEAGRSLKS--VMDEFGISKSTFYDIKKNKKLILDFVLKQDMPL 63
Query: 61 VASTCRKTNKLSPYDKLEGLLIAWFQQIRAAGLPVKGIILKEKALRIAEELGMDDFTASN 120
V + RK + Y ++ + W+QQ R+AG+PV+G+ L+ A R A G DF AS
Sbjct: 64 VGAEKRKRTTGAKYGDVDDAVYMWYQQKRSAGVPVRGVELQAAAERFARCFGRTDFKAST 123
Query: 121 GWLDRFRRRHGVVSCSGVARARARNAAPRTPAAPASPAAVPSEGSGGSTTGWRAREEQPP 180
GWL RFR RH + + G + + + + E
Sbjct: 124 GWLFRFRNRHAIGNRKGCGEQVLSSVSENVEPFRQKLSMIIKE----------------- 166
Query: 181 SVAEGYASQDVFSATETSLWYDFLPDQAAGLCGGDGRPRQA--TQRLSVLLCANADGSEK 238
E ++S ET L++ +P+ + P + +RLS LCANADG+ K
Sbjct: 167 ---EKLCLAQLYSGDETDLFWKSMPENSQASRKDICLPGKKINKERLSAFLCANADGTHK 223
Query: 239 LPPLVAGKSAKPRA---GQAGLPCDYTANSKGGVTTQALA-----------KYLKALDTR 284
L ++ GKS P++ + LP Y + T + + ++ + R
Sbjct: 224 LKSIIIGKSKLPKSVKEDTSTLPVIYKPSKDVWFTRELFSEWFFQNFVPEVRHFQLNVLR 283
Query: 285 MAAESRRVLLLAGRLAA----QSLDTSGLRHVQLAFFPPGT---VHPLERGVVQQVKGHY 337
E R LLL A +SL TS ++ FFP T + P+ +GV+ K Y
Sbjct: 284 FHDEDVRALLLLDSCPAHPSSESL-TSEDGRIKCMFFPHNTSTLIQPMNQGVILSCKRLY 342
Query: 338 RQAMLLKAMAALEGQDP---------SGLQL-GLTEALHFVAAAWQAVEPSDIAACFR-- 385
R L +++ E D S +++ + A+ A +W+ V+ IA +
Sbjct: 343 RWKQLEESLVIFEESDDEQEKGDKGVSKIKIYNIKSAIFNWAKSWEEVKQITIANAWENL 402
Query: 386 ------EAGFGGGPNATITTSLKSEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEG 439
E F G + L+ GE E + +++ G +EE+G + +GG
Sbjct: 403 LYKKEPEYDFQGLEHGDYREILEKCGELETKLDDDRVWLNG----DEEKGCLLKTKGGIT 458
Query: 440 EELGEEEEVEEEGDVDSDEEEEEDEESSSEGLEAEDWAQGVVEAGGSF 487
+E+ V++ G+ E++ E S E+ D+ V+A F
Sbjct: 459 KEV-----VQKGGEA----EKQTAEFKLSAVRESLDYLLDFVDATPEF 497
>gi|117938293 jerky isoform a [Homo sapiens]
Length = 568
Score = 108 bits (270), Expect = 1e-23
Identities = 122/432 (28%), Positives = 183/432 (42%), Gaps = 63/432 (14%)
Query: 4 KRRQLTFREKSRIIQEVEENPDLRKGEIARRFNIPPSTLSTILKNKRAILA--SERKYGV 61
KR LT +EK I +E+ + RK + + +N+ STL I +K +L +
Sbjct: 16 KRVVLTLKEKIDICTRLEKG-ESRKA-LMQEYNVGMSTLYDIRAHKAQLLRFFASSDSNK 73
Query: 62 ASTCRKTNKLSPYDKLEGLLIAWFQQIRAAGLPVKGIILKEKALRIAEELGMDD-FTASN 120
A R+T + L+ +L WF R+ G+PV G +L EKA E++ + + S
Sbjct: 74 ALEQRRTLHTPKLEHLDRVLYEWFLGKRSEGVPVSGPMLIEKAKDFYEQMQLTEPCVFSG 133
Query: 121 GWLDRFRRRHGV--VSCSGVARARARNAAPRTPAAPASPAAVPSEGSGGSTTGWRAREEQ 178
GWL RF+ RHG+ + S ++ AA + A S AA
Sbjct: 134 GWLWRFKARHGIKKLDASSEKQSADHQAAEQFCAFFRSLAA------------------- 174
Query: 179 PPSVAEGYASQDVFSATETSLWYDFLPDQAAGLCGGDGRPRQATQRLSVLLCANADGSEK 238
G +++ V++A ET L++ LP+ G P+Q RL+VL+CANA GS +
Sbjct: 175 ----EHGLSAEQVYNADETGLFWRCLPNPTPE-GGAVPGPKQGKDRLTVLMCANATGSHR 229
Query: 239 LPPLVAGKSAKPRA--GQAGLPCDYTANSKGGVTTQALAKYLKALDTRMAAESRRVLLLA 296
L PL GK + PRA G LP Y A V + + + + E R + L
Sbjct: 230 LKPLAIGKCSGPRAFKGIQHLPVAYKAQGNAWVDKEIFSDWFHHIFVPSVREHFRTIGLP 289
Query: 297 GRLAAQSLDTSGLRHVQLA----------FFPPGT---VHPLERGVVQQVKGHYRQAMLL 343
A L S H Q A F P V P+E+G+ + ++ +
Sbjct: 290 EDSKAVLLLDSSRAHPQEAELVSSNVFTIFLPASVASLVQPMEQGIRRDFMRNF-----I 344
Query: 344 KAMAALEGQDPSGLQLGLTEALHFVAAAWQAVEPSDIAACFREAGFGGGPNATITTSLKS 403
L+G + + +A+ VA AW AV PS + FR A P+ +
Sbjct: 345 NPPVPLQGPH---ARYNMNDAIFSVACAWNAV-PSHV---FRRAWRKLWPSVAF-----A 392
Query: 404 EGEEEEEEEEEE 415
EG EEE E E
Sbjct: 393 EGSSSEEELEAE 404
>gi|117938295 jerky isoform b [Homo sapiens]
Length = 556
Score = 108 bits (270), Expect = 1e-23
Identities = 122/432 (28%), Positives = 183/432 (42%), Gaps = 63/432 (14%)
Query: 4 KRRQLTFREKSRIIQEVEENPDLRKGEIARRFNIPPSTLSTILKNKRAILA--SERKYGV 61
KR LT +EK I +E+ + RK + + +N+ STL I +K +L +
Sbjct: 16 KRVVLTLKEKIDICTRLEKG-ESRKA-LMQEYNVGMSTLYDIRAHKAQLLRFFASSDSNK 73
Query: 62 ASTCRKTNKLSPYDKLEGLLIAWFQQIRAAGLPVKGIILKEKALRIAEELGMDD-FTASN 120
A R+T + L+ +L WF R+ G+PV G +L EKA E++ + + S
Sbjct: 74 ALEQRRTLHTPKLEHLDRVLYEWFLGKRSEGVPVSGPMLIEKAKDFYEQMQLTEPCVFSG 133
Query: 121 GWLDRFRRRHGV--VSCSGVARARARNAAPRTPAAPASPAAVPSEGSGGSTTGWRAREEQ 178
GWL RF+ RHG+ + S ++ AA + A S AA
Sbjct: 134 GWLWRFKARHGIKKLDASSEKQSADHQAAEQFCAFFRSLAA------------------- 174
Query: 179 PPSVAEGYASQDVFSATETSLWYDFLPDQAAGLCGGDGRPRQATQRLSVLLCANADGSEK 238
G +++ V++A ET L++ LP+ G P+Q RL+VL+CANA GS +
Sbjct: 175 ----EHGLSAEQVYNADETGLFWRCLPNPTPE-GGAVPGPKQGKDRLTVLMCANATGSHR 229
Query: 239 LPPLVAGKSAKPRA--GQAGLPCDYTANSKGGVTTQALAKYLKALDTRMAAESRRVLLLA 296
L PL GK + PRA G LP Y A V + + + + E R + L
Sbjct: 230 LKPLAIGKCSGPRAFKGIQHLPVAYKAQGNAWVDKEIFSDWFHHIFVPSVREHFRTIGLP 289
Query: 297 GRLAAQSLDTSGLRHVQLA----------FFPPGT---VHPLERGVVQQVKGHYRQAMLL 343
A L S H Q A F P V P+E+G+ + ++ +
Sbjct: 290 EDSKAVLLLDSSRAHPQEAELVSSNVFTIFLPASVASLVQPMEQGIRRDFMRNF-----I 344
Query: 344 KAMAALEGQDPSGLQLGLTEALHFVAAAWQAVEPSDIAACFREAGFGGGPNATITTSLKS 403
L+G + + +A+ VA AW AV PS + FR A P+ +
Sbjct: 345 NPPVPLQGPH---ARYNMNDAIFSVACAWNAV-PSHV---FRRAWRKLWPSVAF-----A 392
Query: 404 EGEEEEEEEEEE 415
EG EEE E E
Sbjct: 393 EGSSSEEELEAE 404
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 103 bits (257), Expect = 5e-22
Identities = 65/137 (47%), Positives = 84/137 (61%), Gaps = 6/137 (4%)
Query: 402 KSEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEEE 461
+ EGE EEEE E E EEEGEGE EEEEGE E EE GEGE GEEEE E +G+ + +E E
Sbjct: 873 EGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGE--GEEEEGEGKGEEEGEEGEG 930
Query: 462 EDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHFLEG-GEDSDSDSEEEDDE 520
E EE EG E ED E G + G +EE + EG GE+ + + EEE+ E
Sbjct: 931 EGEEEEGEG-EGEDGEGEGEEEEGEW--EGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGE 987
Query: 521 EEDDEDEDDDDDEEDGD 537
E +E+E +++ EE+G+
Sbjct: 988 GEGEEEEGEEEGEEEGE 1004
Score = 97.8 bits (242), Expect = 2e-20
Identities = 67/155 (43%), Positives = 85/155 (54%), Gaps = 22/155 (14%)
Query: 407 EEEEEEEEEEEEEGEGEEEEEEGEEEEEEG------GEGEELGEEEEVEEEGDVDSDEEE 460
EE + E EEEEEEGEGEEEE EGEEEE EG G+GEE GEE E EEEG+ E E
Sbjct: 820 EEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGE 879
Query: 461 EE------DEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHFLEGGEDSDSDS 514
EE +EE EG E E +G E G G +EE + E GE+ + +
Sbjct: 880 EEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGE----GEEEEGEGKG---EEEGEEGEGEG 932
Query: 515 EEEDDEEEDDEDEDDDDDEE---DGDEVPVPSFGE 546
EEE+ E E ++ E + ++EE +G+E GE
Sbjct: 933 EEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGE 967
Score = 94.4 bits (233), Expect = 3e-19
Identities = 66/155 (42%), Positives = 83/155 (53%), Gaps = 21/155 (13%)
Query: 402 KSEGEEEEEEEEEEEEEEGEGEEE----EEEGEEEEEEG------GEGEE-----LGEEE 446
+ EGEEE E E EEEE EG+GEEE E EGEEEE EG GEGEE GEEE
Sbjct: 901 EGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEE 960
Query: 447 EVEEEGDVDSD------EEEEEDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPT 500
E E EG+ + + E E E+EE EG E E +G E G G EE +
Sbjct: 961 EGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGE 1020
Query: 501 LHFLEGGEDSDSDSEEEDDEEEDDEDEDDDDDEED 535
+ GE+ + + EEE+ EEE +E E + + EE+
Sbjct: 1021 VEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEEN 1055
Score = 93.6 bits (231), Expect = 5e-19
Identities = 62/170 (36%), Positives = 88/170 (51%), Gaps = 42/170 (24%)
Query: 402 KSEGEEEEEEEEEE--------------EEEEGEGEEEEEEGEEEEEEGGEGEELGEEEE 447
K +GEE+E++E E+ EEE GEGEEEE + EEEEE+ GEG+E GE EE
Sbjct: 704 KRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEE 763
Query: 448 V-------------------EEEGDVDSDEEEEEDEESSSEGLEAEDWAQGVVEAGGSFG 488
V EE+G+ + D+ E E+EE+ G E E+ G VE G
Sbjct: 764 VEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEE--GGEVEGGEVEE 821
Query: 489 AYGAQEEAQCPTLHFLEGGEDSDSDSEEEDDEEEDDEDEDDDDDEEDGDE 538
G +EE + E GE + + E E++E E +E+E + EE+G+E
Sbjct: 822 GKGEREEEE-------EEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEE 864
Score = 93.2 bits (230), Expect = 6e-19
Identities = 62/138 (44%), Positives = 81/138 (58%), Gaps = 13/138 (9%)
Query: 402 KSEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEE-EVEEEGDVDSDEEE 460
+ EGE E EEE E E EEGEGE EEEEGE E EE EGEE GEEE E EEEG+ + +EEE
Sbjct: 959 EEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEE-EEGEEEGEEEGEGEEEGEGEGEEEE 1017
Query: 461 EEDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHFLEGGEDSDSDSEEEDDE 520
E + E EG E E +G E G G +E EG E+ + EEE++E
Sbjct: 1018 EGEVEGEVEGEEGE--GEGEEEEGEEEGEEREKEG---------EGEENRRNREEEEEEE 1066
Query: 521 EEDDEDEDDDDDEEDGDE 538
+ E +++++ +DG+E
Sbjct: 1067 GKYQETGEEENERQDGEE 1084
Score = 90.9 bits (224), Expect = 3e-18
Identities = 60/149 (40%), Positives = 83/149 (55%), Gaps = 19/149 (12%)
Query: 402 KSEGEEEEEEEEEEEEEEGEGEEEEEEGE-EEEEEGGE------GEELGEEEEVEEEG-- 452
K E +EE+ EEE ++GEGEEEE EG EE+EEGGE E GE EE EEEG
Sbjct: 776 KKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEG 835
Query: 453 ---DVDSDEEEEEDEESSSEGLEAEDWAQGVVEAGGSFG-AYGAQEEAQCPTLHFLEGGE 508
+ + +EEE E EE EG E+ +G E G G G +EE + EG E
Sbjct: 836 EEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEG------EGEE 889
Query: 509 DSDSDSEEEDDEEEDDEDEDDDDDEEDGD 537
+ + + EEE+ E E +E+ + + +EE+G+
Sbjct: 890 EGEGEGEEEEGEGEGEEEGEGEGEEEEGE 918
Score = 90.5 bits (223), Expect = 4e-18
Identities = 66/157 (42%), Positives = 86/157 (54%), Gaps = 32/157 (20%)
Query: 402 KSEGEEEEEEEEEEEEEEG-------------EGEEEEEEGEEEEEEGGEGEE---LGEE 445
+ EGEEEE E EE+EEG E EEEEEEGE EEEE GEGEE GEE
Sbjct: 793 QGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEE-GEGEEEEGEGEE 851
Query: 446 EEVEEEGDVDSD--EEEEEDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHF 503
EE E +G+ + + E EEE EE EG E E +G E G G +EE +
Sbjct: 852 EEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGE----GEEEEGEG----- 902
Query: 504 LEGGEDSDSDSEEEDDE---EEDDEDEDDDDDEEDGD 537
EG E+ + + EEE+ E EE+ E+ + + +EE+G+
Sbjct: 903 -EGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGE 938
Score = 89.7 bits (221), Expect = 7e-18
Identities = 67/172 (38%), Positives = 89/172 (51%), Gaps = 26/172 (15%)
Query: 402 KSEGEEEEEEEEEE------EEEEGEGEEEEEEGEEEEEEGGEG----------EELGEE 445
+ EGEEEE E E E EEEEGE E EEEEGE E EE GEG EE GE
Sbjct: 929 EGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEG 988
Query: 446 EEVEEEGDVDSDEEEEEDEESSSEGLEAEDW-AQGVVEAGGSFGAYGAQEEAQCPTLHFL 504
E EEEG+ + +EE E +EE EG E E+ +G VE G G +EE +
Sbjct: 989 EGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGE-GEEEEGE------- 1040
Query: 505 EGGEDSDSDSE-EEDDEEEDDEDEDDDDDEEDGDEVPVPSFGEAMAYFAMVK 555
E GE+ + + E EE+ ++E+E++ +E G+E GE + +K
Sbjct: 1041 EEGEEREKEGEGEENRRNREEEEEEEGKYQETGEEENERQDGEEYKKVSKIK 1092
Score = 72.8 bits (177), Expect = 9e-13
Identities = 56/161 (34%), Positives = 82/161 (50%), Gaps = 30/161 (18%)
Query: 404 EGEEEEEEEEEEEEEEGEGEEEEE-------EGEEEEEEGGEGEELGEEEEVEEEGDVDS 456
EGE+E E+EE ++ +GE +E++E E +E EEGGE EE GE EE EEGD +
Sbjct: 691 EGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGE-EEHGEGEE--EEGDREE 747
Query: 457 DEEEE------------EDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTL--- 501
+EE+E E E EG ++ G E G G G EE +
Sbjct: 748 EEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEE 807
Query: 502 ----HFLEGGEDSDSDSEEEDDEEE-DDEDEDDDDDEEDGD 537
+EGGE + E E++EEE + E+E+ + +EE+G+
Sbjct: 808 KEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGE 848
Score = 57.8 bits (138), Expect = 3e-08
Identities = 41/145 (28%), Positives = 69/145 (47%), Gaps = 9/145 (6%)
Query: 404 EGEEEEEEEEE----EEEEEGEGEEEEEEGEEEEEEGGEGEEL-----GEEEEVEEEGDV 454
+ EE E+ E++ E E GEGE+E E EE ++ GE +E G ++E +E +
Sbjct: 670 QDEEREKGEKDKGRGEMERPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEE 729
Query: 455 DSDEEEEEDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHFLEGGEDSDSDS 514
+EE E EE + E E+ E G G +E+ + G++ +
Sbjct: 730 GGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEE 789
Query: 515 EEEDDEEEDDEDEDDDDDEEDGDEV 539
E + E E++E E +++E+G EV
Sbjct: 790 EGDQGEGEEEETEGRGEEKEEGGEV 814
Score = 50.8 bits (120), Expect = 3e-06
Identities = 29/70 (41%), Positives = 43/70 (61%), Gaps = 1/70 (1%)
Query: 401 LKSEGEEEEEEEE-EEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEE 459
++ E E EE E E EEEE E EGEE E+EGE EE EE EE + +E G+ +++ +
Sbjct: 1021 VEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQETGEEENERQ 1080
Query: 460 EEEDEESSSE 469
+ E+ + S+
Sbjct: 1081 DGEEYKKVSK 1090
Score = 50.4 bits (119), Expect = 5e-06
Identities = 42/147 (28%), Positives = 71/147 (48%), Gaps = 33/147 (22%)
Query: 402 KSEGEEEEEEEEEEEE--EEGEG-----EEEEEEGEEEEEEGGEGEELGE-EEEVEEEGD 453
KS GE E+ E + EEG ++EE E E+++ GE E GE E+E+ E+ +
Sbjct: 642 KSVGEAEDGPEGRGDGTCEEGSSGAEHWQDEEREKGEKDKGRGEMERPGEGEKELAEKEE 701
Query: 454 VDSDEEEEEDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHFLEGGEDSDSD 513
+ EE++++ +G + E +E + EGGE+ +
Sbjct: 702 WKKRDGEEQEQKEREQGHQKE-----------------RNQEME-------EGGEEEHGE 737
Query: 514 SEEED-DEEEDDEDEDDDDDEEDGDEV 539
EEE+ D EE++E E + +E +G+EV
Sbjct: 738 GEEEEGDREEEEEKEGEGKEEGEGEEV 764
>gi|22209001 hypothetical protein LOC200765 [Homo sapiens]
Length = 591
Score = 95.1 bits (235), Expect = 2e-19
Identities = 99/420 (23%), Positives = 174/420 (41%), Gaps = 64/420 (15%)
Query: 5 RRQLTFREKSRIIQEVEENPDLRKGEIARRFNIPPSTLSTILKNKRAILASERKYGVAST 64
R LT +K +I+ EE + K EI RR + T+S ++ K L + +T
Sbjct: 12 RTSLTLNQKLEMIKLSEEG--MSKAEIGRRLGLLRQTVSQVVNAKEKFLKEVKSATPMNT 69
Query: 65 CRKTNKLSPYDKLEGLLIAWFQQIRAAGLPVKGIILKEKALRI--------AEELGMDDF 116
+ S +E +L+ W + + +P+ +++ KAL + E + F
Sbjct: 70 RMIRKRNSLIADMEKVLVVWIEDQTSRNIPLSQSLIQNKALTLFNSMKAERGVEAAEEKF 129
Query: 117 TASNGWLDRFRRR---HGVVSCSGVARARARNAAPRTPAAPASPAAVPSEGSGGSTTGWR 173
AS GW RF+ R H + + A A AA + P + A + EG
Sbjct: 130 EASRGWFMRFKERSHFHNIKAQGEAASADVEAAA----SYPEALAKIIDEG--------- 176
Query: 174 AREEQPPSVAEGYASQDVFSATETSLWYDFLPDQAAGLCGGDGRP--RQATQRLSVLLCA 231
GY Q +F+ ET+ ++ +P + P + + RL++LL A
Sbjct: 177 -----------GYTKQQIFNVDETAFYWKKMPSRTFIAREEKSVPGFKASKDRLTLLLGA 225
Query: 232 NADGSEKLPPLVAGKSAKPRA----GQAGLPCDYTANSKGGVT----TQALAKYLKALDT 283
NA G KL P++ S PRA ++ LP Y NSK +T T +Y K
Sbjct: 226 NAAGDFKLKPMLIYHSENPRALKNYTKSTLPVLYKWNSKARMTAHLFTAWFTEYFKPTVE 285
Query: 284 RMAAESR---RVLLLAGRLAAQSLDTSGL-RHVQLAFFPPGT---VHPLERGVVQQVKGH 336
+E + ++LLL + + + + F P T + P+++GV+ K +
Sbjct: 286 TYCSEKKIPFKILLLIDNAPSHPRALMEIYEEINVIFMPANTTSILQPMDQGVISTFKSY 345
Query: 337 YRQAMLLKAMAALEG--QDPSGLQ--------LGLTEALHFVAAAWQAVEPSDIAACFRE 386
Y + KA+AA++ D SG + +A+ + +W+ V+ S + +++
Sbjct: 346 YLRNTFHKALAAMDSDVSDGSGQSKLKTFWKGFTILDAIKNIRDSWEEVKLSTLTGVWKK 405
>gi|55956788 nucleolin [Homo sapiens]
Length = 710
Score = 87.4 bits (215), Expect = 3e-17
Identities = 49/162 (30%), Positives = 85/162 (52%), Gaps = 16/162 (9%)
Query: 377 PSDIAACFREAGFGGGPNATITTSLKSEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEG 436
P A G G NA K + +EEE+++ EE+EE+ E E+E+E+ E
Sbjct: 122 PGKKGAAIPAKGAKNGKNAK-----KEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMK 176
Query: 437 GEGEELGEEEEVEEEGDVDSDEEEEEDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEA 496
E+E +E+ + D D++++E+++S E +E A G A +A
Sbjct: 177 AAAAAPASEDEDDEDDEDDEDDDDDEEDDSEEEAMET-------TPAKGKKAAKVVPVKA 229
Query: 497 QCPTLHFLEGGEDSDSDSEEEDDEEEDDEDEDDDDDEEDGDE 538
+ + E ++ + D +E+DD++EDDED+DD+DDEE+ +E
Sbjct: 230 K----NVAEDEDEEEDDEDEDDDDDEDDEDDDDEDDEEEEEE 267
Score = 55.8 bits (133), Expect = 1e-07
Identities = 32/118 (27%), Positives = 61/118 (51%), Gaps = 14/118 (11%)
Query: 393 PNATITTSLKSEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELG--------- 443
P A + E+E++E++E++E++ + EE++ E E E +G++
Sbjct: 172 PAAMKAAAAAPASEDEDDEDDEDDEDDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKN 231
Query: 444 -----EEEEVEEEGDVDSDEEEEEDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEA 496
+EEE +E+ D D DE++E+D++ E E E+ + V EA G A+++A
Sbjct: 232 VAEDEDEEEDDEDEDDDDDEDDEDDDDEDDEEEEEEEEEEPVKEAPGKRKKEMAKQKA 289
Score = 55.5 bits (132), Expect = 1e-07
Identities = 33/129 (25%), Positives = 60/129 (46%), Gaps = 24/129 (18%)
Query: 427 EEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEEEEDEESSSEGLEAEDWAQGVVEAGGS 486
++G +G + + ++E+ +EE D DS+E+EE+DE+ + E E A A
Sbjct: 124 KKGAAIPAKGAKNGKNAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAA-- 181
Query: 487 FGAYGAQEEAQCPTLHFLEGGEDSDSDSEEEDDEEEDDEDEDDDDDEEDGDEVPVPSFGE 546
+ D ++EDDE+++D+D+D++DD E+ P+ G+
Sbjct: 182 ----------------------PASEDEDDEDDEDDEDDDDDEEDDSEEEAMETTPAKGK 219
Query: 547 AMAYFAMVK 555
A VK
Sbjct: 220 KAAKVVPVK 228
Score = 50.4 bits (119), Expect = 5e-06
Identities = 36/169 (21%), Positives = 72/169 (42%), Gaps = 10/169 (5%)
Query: 391 GGPNATITTSLKSEGEEEEEEEEEEEEEEGEGEE---EEEEGEEEEEEGGEGEELGEEEE 447
G P + E + E+EE E+EE++ GEE +++G++ + + ++
Sbjct: 12 GDPKKMAPPPKEVEEDSEDEEMSEDEEDDSSGEEVVIPQKKGKKAAATSAKKVVVSPTKK 71
Query: 448 VEEEGDVDSDEEEEEDEESSSEGLEAEDWAQGVVEAGGSFGAYG-------AQEEAQCPT 500
V + +++ + A+ V G G ++ A P
Sbjct: 72 VAVATPAKKAAVTPGKKAAATPAKKTVTPAKAVTTPGKKGATPGKALVATPGKKGAAIPA 131
Query: 501 LHFLEGGEDSDSDSEEEDDEEEDDEDEDDDDDEEDGDEVPVPSFGEAMA 549
G DS+EE+D++ ++++EDD+D++ED DE+ + A A
Sbjct: 132 KGAKNGKNAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAA 180
Score = 47.8 bits (112), Expect = 3e-05
Identities = 21/70 (30%), Positives = 45/70 (64%)
Query: 403 SEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEEEE 462
+E E+EEE++E+E++++ E +E++++ ++EEEE E EE +E + + ++ + E
Sbjct: 233 AEDEDEEEDDEDEDDDDDEDDEDDDDEDDEEEEEEEEEEPVKEAPGKRKKEMAKQKAAPE 292
Query: 463 DEESSSEGLE 472
++ EG E
Sbjct: 293 AKKQKVEGTE 302
Score = 42.4 bits (98), Expect = 0.001
Identities = 17/67 (25%), Positives = 44/67 (65%)
Query: 402 KSEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEEE 461
+ + E+E+++++E++E++ + ++EEEE EEEEE E ++E +++ ++ +++
Sbjct: 239 EEDDEDEDDDDDEDDEDDDDEDDEEEEEEEEEEPVKEAPGKRKKEMAKQKAAPEAKKQKV 298
Query: 462 EDEESSS 468
E E ++
Sbjct: 299 EGTEPTT 305
Score = 38.9 bits (89), Expect = 0.014
Identities = 17/61 (27%), Positives = 38/61 (62%)
Query: 414 EEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEEEEDEESSSEGLEA 473
E+E+EE + E+E+++ +E++E+ + ++ EEEE EEE ++ + +++ EA
Sbjct: 234 EDEDEEEDDEDEDDDDDEDDEDDDDEDDEEEEEEEEEEPVKEAPGKRKKEMAKQKAAPEA 293
Query: 474 E 474
+
Sbjct: 294 K 294
Score = 32.0 bits (71), Expect = 1.7
Identities = 13/46 (28%), Positives = 26/46 (56%)
Query: 515 EEEDDEEEDDEDEDDDDDEEDGDEVPVPSFGEAMAYFAMVKRYLTS 560
+E +++ ED+E +D++D+ G+EV +P A K+ + S
Sbjct: 22 KEVEEDSEDEEMSEDEEDDSSGEEVVIPQKKGKKAAATSAKKVVVS 67
>gi|4759128 solute carrier family 24 (sodium/potassium/calcium
exchanger), member 1 [Homo sapiens]
Length = 1099
Score = 84.3 bits (207), Expect = 3e-16
Identities = 55/159 (34%), Positives = 85/159 (53%), Gaps = 31/159 (19%)
Query: 402 KSEGE---EEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVE--------- 449
+S GE EE E E E EE G E + EGE E E G+GEE +E E E
Sbjct: 751 ESTGEMPGEEGETAGEGETEEKSGGETQPEGEGETETQGKGEECEDENEAEGKGDNEGED 810
Query: 450 ------EEGDVDSDEEEEEDEESSSEGL-EAEDWAQGVVEAGGSFGAYGAQEEAQCPTLH 502
E+G++ +E E E +E S+E EA++ +GV + GGS G +EE
Sbjct: 811 EGEIHAEDGEMKGNEGETESQELSAENHGEAKNDEKGVEDGGGSDGGDSEEEE------- 863
Query: 503 FLEGGEDSDSDSEEEDDEEEDDEDEDDDDDEEDGDEVPV 541
E+ + EEE++EE+++E+E+++++EE G+E P+
Sbjct: 864 -----EEEEEQEEEEEEEEQEEEEEEEEEEEEKGNEEPL 897
Score = 59.7 bits (143), Expect = 7e-09
Identities = 49/177 (27%), Positives = 80/177 (45%), Gaps = 40/177 (22%)
Query: 402 KSEGEEEEEEEEE----------------EEEEEGEGEEEEEEGEEEEEEGGEGEELGEE 445
K+E + EEEE + +++E G+E+ E E E GE E E
Sbjct: 707 KAESKPEEEEPAKLPAVTVTPAPVPDIKGDQKENPGGQEDVAEAESTGEMPGEEGETAGE 766
Query: 446 EEVEEEGDVDSDEEEEEDEESSSEGLEAED--WAQGV---------------VEAGGSFG 488
E EE+ ++ E E + E+ +G E ED A+G E G+ G
Sbjct: 767 GETEEKSGGETQPEGEGETETQGKGEECEDENEAEGKGDNEGEDEGEIHAEDGEMKGNEG 826
Query: 489 AYGAQE-------EAQCPTLHFLEGGEDSDSDSEEEDDEEEDDEDEDDDDDEEDGDE 538
+QE EA+ +GG DSEEE++EEE+ E+E++++++E+ +E
Sbjct: 827 ETESQELSAENHGEAKNDEKGVEDGGGSDGGDSEEEEEEEEEQEEEEEEEEQEEEEE 883
Score = 55.1 bits (131), Expect = 2e-07
Identities = 35/88 (39%), Positives = 48/88 (54%), Gaps = 7/88 (7%)
Query: 391 GGPNATITTSLKSEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEE 450
G T + L +E E + +E+ E+ G + + E EEEEEE E EE EEEE EE
Sbjct: 823 GNEGETESQELSAENHGEAKNDEKGVEDGGGSDGGDSEEEEEEEEEQEEEE--EEEEQEE 880
Query: 451 EGDVDSDEEEEEDEESSSEGLEAEDWAQ 478
E +EEEEE+EE +E + DW +
Sbjct: 881 E-----EEEEEEEEEKGNEEPLSLDWPE 903
Score = 53.1 bits (126), Expect = 7e-07
Identities = 36/111 (32%), Positives = 50/111 (45%), Gaps = 34/111 (30%)
Query: 393 PNATITTSLKSEGEEEEEEEEEEEEEEGEGEEEEE-----------EGEEEEEE------ 435
P T + +GEE E+E E E + + EGE+E E EGE E +E
Sbjct: 779 PEGEGETETQGKGEECEDENEAEGKGDNEGEDEGEIHAEDGEMKGNEGETESQELSAENH 838
Query: 436 -----------------GGEGEELGEEEEVEEEGDVDSDEEEEEDEESSSE 469
GG+ EE EEEE +EE + + ++EEEE+EE E
Sbjct: 839 GEAKNDEKGVEDGGGSDGGDSEEEEEEEEEQEEEEEEEEQEEEEEEEEEEE 889
Score = 46.2 bits (108), Expect = 9e-05
Identities = 24/44 (54%), Positives = 27/44 (61%)
Query: 390 GGGPNATITTSLKSEGEEEEEEEEEEEEEEGEGEEEEEEGEEEE 433
GG + E E+EEEEEEEE+EEE E EEEEEE EE
Sbjct: 852 GGSDGGDSEEEEEEEEEQEEEEEEEEQEEEEEEEEEEEEKGNEE 895
Score = 45.1 bits (105), Expect = 2e-04
Identities = 25/47 (53%), Positives = 31/47 (65%), Gaps = 1/47 (2%)
Query: 386 EAGFGGGPNATITTSLKSEGEEEEEEEEEEEEEEGEGEEEEEEGEEE 432
+ G G ++ + E EEEEEEEE+EEEEE E EEEEE+G EE
Sbjct: 850 DGGGSDGGDSEEEEEEEEEQEEEEEEEEQEEEEE-EEEEEEEKGNEE 895
>gi|155030232 proline, glutamic acid and leucine rich protein 1 [Homo
sapiens]
Length = 1130
Score = 82.0 bits (201), Expect = 1e-15
Identities = 72/172 (41%), Positives = 84/172 (48%), Gaps = 18/172 (10%)
Query: 390 GGGPNA-----TI----TTSLKSEGEEEEEEEEEEEEEEGEGEEEEEEGEEEE-EEGGEG 439
GGGP A T+ ++ + E EEEEEEEEEEEEEE E EEEEE EEE EE E
Sbjct: 868 GGGPPALEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEE 927
Query: 440 EELGEEEEVEEEGDVDSDEEEEEDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCP 499
EE EEE EEEG+++ +EEEEEDEE E E ED G AGG P
Sbjct: 928 EEEFEEEFEEEEGELE-EEEEEEDEEEEEELEEVEDLEFGT--AGGEVEEGAPPPPTLPP 984
Query: 500 TLHFLEGGEDSDSDSEEE-----DDEEEDDEDEDDDDDEEDGDEVPVPSFGE 546
L E + E E + EE E+E D +PS GE
Sbjct: 985 ALPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAPEALPSQGE 1036
Score = 39.7 bits (91), Expect = 0.008
Identities = 17/54 (31%), Positives = 34/54 (62%)
Query: 485 GSFGAYGAQEEAQCPTLHFLEGGEDSDSDSEEEDDEEEDDEDEDDDDDEEDGDE 538
G+ G G + T+ + ++ + + EEE++EEE++E+E++D +EE+ DE
Sbjct: 864 GTPGGGGPPALEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDE 917
Score = 36.2 bits (82), Expect = 0.088
Identities = 50/203 (24%), Positives = 74/203 (36%), Gaps = 74/203 (36%)
Query: 402 KSEGEEEEEEEEEEEEEEGEGEEEE----------------------------------- 426
+ EGE EEEEEEE+EEEE E EE E
Sbjct: 937 EEEGELEEEEEEEDEEEEEELEEVEDLEFGTAGGEVEEGAPPPPTLPPALPPPESPPKVQ 996
Query: 427 -------------EEGEEEEEEGGE------GEELGEEEEVEEEGDVDS----DEEEEED 463
EE EEE G + E L + EVE EG+ + +E E+
Sbjct: 997 PEPEPEPGLLLEVEEPGTEEERGADTAPTLAPEALPSQGEVEREGESPAAGPPPQELVEE 1056
Query: 464 EESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHFLEGGEDSDSDSEEEDDEEED 523
E S+ L E+ G ++ Q P E ++++++E ++E+D
Sbjct: 1057 EPSAPPTLLEEETEDG-------------SDKVQPPPETPAEEEMETETEAEALQEKEQD 1103
Query: 524 DED---EDDDDDEEDGDEVPVPS 543
D D D D ++ P P+
Sbjct: 1104 DTAAMLADFIDCPPDDEKPPPPT 1126
Score = 33.5 bits (75), Expect = 0.57
Identities = 24/78 (30%), Positives = 39/78 (50%), Gaps = 10/78 (12%)
Query: 400 SLKSEGEEEEEEEEEEEEEEGEGEEEEEEG------EEEEEEGGE----GEELGEEEEVE 449
+L S+GE E E E + EEE EEE E+G + E EEE+E
Sbjct: 1030 ALPSQGEVEREGESPAAGPPPQELVEEEPSAPPTLLEEETEDGSDKVQPPPETPAEEEME 1089
Query: 450 EEGDVDSDEEEEEDEESS 467
E + ++ +E+E+D+ ++
Sbjct: 1090 TETEAEALQEKEQDDTAA 1107
Score = 32.3 bits (72), Expect = 1.3
Identities = 36/141 (25%), Positives = 52/141 (36%), Gaps = 21/141 (14%)
Query: 393 PNATITTSLKSEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEG---EELGEEEE-- 447
P + ++ G EEE + E + E E E E G +EL EEE
Sbjct: 1001 PEPGLLLEVEEPGTEEERGADTAPTLAPEALPSQGEVEREGESPAAGPPPQELVEEEPSA 1060
Query: 448 ----VEEEGDVDSDEEEEEDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHF 503
+EEE + SD+ + E + E +E E A+ + QE+ Q T
Sbjct: 1061 PPTLLEEETEDGSDKVQPPPETPAEEEMETETEAEAL------------QEKEQDDTAAM 1108
Query: 504 LEGGEDSDSDSEEEDDEEEDD 524
L D D E+ E D
Sbjct: 1109 LADFIDCPPDDEKPPPPTEPD 1129
>gi|13540523 nucleosomal binding protein 1 [Homo sapiens]
Length = 282
Score = 79.0 bits (193), Expect = 1e-14
Identities = 49/168 (29%), Positives = 90/168 (53%), Gaps = 18/168 (10%)
Query: 390 GGGPNATITTSLKSEGEEEEEEEEEEEEEEGEG--EEEEEEGEEEEEEGGEGEELGEEEE 447
GG + +K+E E+++E+EE++ EE+GE E+++E+GEE+ +E G E GE+ +
Sbjct: 112 GGEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEAGKEDKDEKGEEDGKEDKNGNEKGEDAK 171
Query: 448 VEEEG--------------DVDSDEEEEEDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQ 493
+E+G + DE+EEED + + +G E ED + + G +
Sbjct: 172 EKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKENEDGKEKGDKKEGK-DVKVKE 230
Query: 494 EEAQCPTLHFLEGGEDSDSDSEEED-DEEEDDEDEDDDDDEEDGDEVP 540
+E + EGG + ++ E+ED EEE+ ++ED+ +++ E P
Sbjct: 231 DEKEREDGKEDEGGNEEEAGKEKEDLKEEEEGKEEDEIKEDDGKKEEP 278
Score = 60.8 bits (146), Expect = 3e-09
Identities = 46/171 (26%), Positives = 79/171 (46%), Gaps = 29/171 (16%)
Query: 394 NATITTSLKSEGEEEEEEEEEEEEEEGEGEEE--------------EEEGEEEEEEGGEG 439
N T E +E E + EEE+ + +EE +E+GEE+ +E G
Sbjct: 104 NIEDATEKGGEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEAGKEDKDEKGEEDGKEDKNG 163
Query: 440 EELGEEEEVEEEG--------------DVDSDEEEEEDEESSSEGLEAEDWAQGVVEAGG 485
E GE+ + +E+G + DE+EEED + + +G E ED + + G
Sbjct: 164 NEKGEDAKEKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKENEDGKEKGDKKEG 223
Query: 486 SFGAYGAQEEAQCPTLHFLEGGEDSDSDSEEEDDEEEDDEDEDDDDDEEDG 536
++E + EGG + ++ E+ED +EE++ E+D+ E+DG
Sbjct: 224 K-DVKVKEDEKEREDGKEDEGGNEEEAGKEKEDLKEEEEGKEEDEIKEDDG 273
Score = 59.3 bits (142), Expect = 1e-08
Identities = 39/145 (26%), Positives = 71/145 (48%), Gaps = 10/145 (6%)
Query: 395 ATITTSLKSEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDV 454
A IT + SE E E +EE E+ +G E++E E + E ++ EE++ EE+G+
Sbjct: 85 AKITEAPASEKEIVEVKEENIEDATEKGGEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEA 144
Query: 455 DSDEEEEEDEESSSEGLEAEDWAQGVVE-AGGSFGAYGAQEEAQCPTLHFLEGGEDSDSD 513
++++E+ EE E + + E G G G E G++ D
Sbjct: 145 GKEDKDEKGEEDGKEDKNGNEKGEDAKEKEDGKKGEDGKGNG---------EDGKEKGED 195
Query: 514 SEEEDDEEEDDEDEDDDDDEEDGDE 538
+EE+D +E + ++++D +E GD+
Sbjct: 196 EKEEEDRKETGDGKENEDGKEKGDK 220
Score = 55.1 bits (131), Expect = 2e-07
Identities = 27/65 (41%), Positives = 45/65 (69%), Gaps = 4/65 (6%)
Query: 402 KSEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEEE 461
K EG++ + +E+E+E E+G+ E+EG EEE G E E+L EEEE +EE ++ D+ ++
Sbjct: 220 KKEGKDVKVKEDEKEREDGK----EDEGGNEEEAGKEKEDLKEEEEGKEEDEIKEDDGKK 275
Query: 462 EDEES 466
E+ +S
Sbjct: 276 EEPQS 280
Score = 52.8 bits (125), Expect = 9e-07
Identities = 42/162 (25%), Positives = 70/162 (43%), Gaps = 17/162 (10%)
Query: 394 NATITTSLKSEGEEEE--EEEEEEEEEEGEG-------------EEEEEEGEEEEEEGGE 438
N + +E ++E EE+ E + GE E +EE E+ E+GGE
Sbjct: 55 NIDTSAQAVAETKQEAVVEEDYNENAKNGEAKITEAPASEKEIVEVKEENIEDATEKGGE 114
Query: 439 GEELGEEEEVEEEGDVDSDEEEEEDE--ESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEA 496
+E E EE D DEE++ +E E+ E + + G + G+ A+E+
Sbjct: 115 KKEAVAAEVKNEEEDQKEDEEDQNEEKGEAGKEDKDEKGEEDGKEDKNGNEKGEDAKEKE 174
Query: 497 QCPTLHFLEGGEDSDSDSEEEDDEEEDDEDEDDDDDEEDGDE 538
+G + + E++ EEED ++ D + EDG E
Sbjct: 175 DGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKENEDGKE 216
Score = 50.1 bits (118), Expect = 6e-06
Identities = 36/104 (34%), Positives = 55/104 (52%), Gaps = 21/104 (20%)
Query: 386 EAGFGGGPNATITTSLKSEGEEEEEEEEEEEEEEG-EGEEEEEEGE------------EE 432
E G G G + K +GE+E+EEE+ +E +G E E+ +E+G+ E+
Sbjct: 180 EDGKGNGEDG------KEKGEDEKEEEDRKETGDGKENEDGKEKGDKKEGKDVKVKEDEK 233
Query: 433 EEEGGEGEELGEEEEVEEEGDVDSDEEE--EEDEESSSEGLEAE 474
E E G+ +E G EEE +E + +EEE EEDE +G + E
Sbjct: 234 EREDGKEDEGGNEEEAGKEKEDLKEEEEGKEEDEIKEDDGKKEE 277
Score = 45.8 bits (107), Expect = 1e-04
Identities = 23/75 (30%), Positives = 48/75 (64%), Gaps = 7/75 (9%)
Query: 404 EGEEEEEEEEEEEEEEGEG----EEEEEEGEEEEEEGGEGEELGEEEE---VEEEGDVDS 456
+G+E E+ +E+ +++EG+ E+E+E + +E+EGG EE G+E+E EEEG +
Sbjct: 207 DGKENEDGKEKGDKKEGKDVKVKEDEKEREDGKEDEGGNEEEAGKEKEDLKEEEEGKEED 266
Query: 457 DEEEEEDEESSSEGL 471
+ +E++ ++ + +
Sbjct: 267 EIKEDDGKKEEPQSI 281
>gi|13569879 acidic (leucine-rich) nuclear phosphoprotein 32 family,
member E isoform 1 [Homo sapiens]
Length = 268
Score = 75.9 bits (185), Expect = 1e-13
Identities = 56/148 (37%), Positives = 76/148 (51%), Gaps = 34/148 (22%)
Query: 399 TSLKSEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDE 458
T L +E+ E + EEE++ +G+E++E EEEE E G E G EEE EEE + D DE
Sbjct: 143 TYLDGFDQEDNEAPDSEEEDDEDGDEDDE--EEEENEAGPPE--GYEEEEEEEEEEDEDE 198
Query: 459 EEEEDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHFLEGGEDSDSDSEEED 518
+E+EDE S G +G E G S Y +EE Q E+ D D EE
Sbjct: 199 DEDEDEAGSELG-------EGEEEVGLS---YLMKEEIQ---------DEEDDDDYVEEG 239
Query: 519 DEEEDDE-----------DEDDDDDEED 535
+EEE++E D +DD +EED
Sbjct: 240 EEEEEEEEGGLRGEKRKRDAEDDGEEED 267
Score = 75.1 bits (183), Expect = 2e-13
Identities = 52/144 (36%), Positives = 75/144 (52%), Gaps = 33/144 (22%)
Query: 404 EGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEEEED 463
+G ++E+ E + EEE + + +E++ EEEE E G E G EEE EEE + D DE+E+ED
Sbjct: 146 DGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPE--GYEEEEEEEEEEDEDEDEDED 203
Query: 464 EESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHFLEGGEDSDSDSEEEDDEEED 523
E S G +G E G S Y +EE Q E+ D D EE +EEE+
Sbjct: 204 EAGSELG-------EGEEEVGLS---YLMKEEIQ---------DEEDDDDYVEEGEEEEE 244
Query: 524 DED------------EDDDDDEED 535
+E+ EDD ++E+D
Sbjct: 245 EEEGGLRGEKRKRDAEDDGEEEDD 268
Score = 46.2 bits (108), Expect = 9e-05
Identities = 32/103 (31%), Positives = 47/103 (45%), Gaps = 33/103 (32%)
Query: 437 GEGEELGEEEEVEEEGDVDSDEEEEEDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEA 496
G +E E + EEE D D DE++EE+EE+ EAG
Sbjct: 147 GFDQEDNEAPDSEEEDDEDGDEDDEEEEEN---------------EAGPP---------- 181
Query: 497 QCPTLHFLEGGEDSDSDSEEEDDEEEDDEDEDDDDDEEDGDEV 539
EG E+ + + EEED++E++DEDE + E +EV
Sbjct: 182 --------EGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEV 216
Score = 40.8 bits (94), Expect = 0.004
Identities = 19/40 (47%), Positives = 27/40 (67%), Gaps = 2/40 (5%)
Query: 503 FLEGGEDSDSDSEEEDDEEEDDEDEDDDDDEEDGDEVPVP 542
+L+G + D+ E D EEEDDED D+DD+EE+ +E P
Sbjct: 144 YLDGFDQEDN--EAPDSEEEDDEDGDEDDEEEEENEAGPP 181
>gi|210147569 acidic (leucine-rich) nuclear phosphoprotein 32
family, member E isoform 2 [Homo sapiens]
Length = 227
Score = 75.9 bits (185), Expect = 1e-13
Identities = 56/148 (37%), Positives = 76/148 (51%), Gaps = 34/148 (22%)
Query: 399 TSLKSEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDE 458
T L +E+ E + EEE++ +G+E++E EEEE E G E G EEE EEE + D DE
Sbjct: 102 TYLDGFDQEDNEAPDSEEEDDEDGDEDDE--EEEENEAGPPE--GYEEEEEEEEEEDEDE 157
Query: 459 EEEEDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHFLEGGEDSDSDSEEED 518
+E+EDE S G +G E G S Y +EE Q E+ D D EE
Sbjct: 158 DEDEDEAGSELG-------EGEEEVGLS---YLMKEEIQ---------DEEDDDDYVEEG 198
Query: 519 DEEEDDE-----------DEDDDDDEED 535
+EEE++E D +DD +EED
Sbjct: 199 EEEEEEEEGGLRGEKRKRDAEDDGEEED 226
Score = 75.1 bits (183), Expect = 2e-13
Identities = 52/144 (36%), Positives = 75/144 (52%), Gaps = 33/144 (22%)
Query: 404 EGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEEEED 463
+G ++E+ E + EEE + + +E++ EEEE E G E G EEE EEE + D DE+E+ED
Sbjct: 105 DGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPE--GYEEEEEEEEEEDEDEDEDED 162
Query: 464 EESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHFLEGGEDSDSDSEEEDDEEED 523
E S G +G E G S Y +EE Q E+ D D EE +EEE+
Sbjct: 163 EAGSELG-------EGEEEVGLS---YLMKEEIQ---------DEEDDDDYVEEGEEEEE 203
Query: 524 DED------------EDDDDDEED 535
+E+ EDD ++E+D
Sbjct: 204 EEEGGLRGEKRKRDAEDDGEEEDD 227
Score = 46.2 bits (108), Expect = 9e-05
Identities = 32/103 (31%), Positives = 47/103 (45%), Gaps = 33/103 (32%)
Query: 437 GEGEELGEEEEVEEEGDVDSDEEEEEDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEA 496
G +E E + EEE D D DE++EE+EE+ EAG
Sbjct: 106 GFDQEDNEAPDSEEEDDEDGDEDDEEEEEN---------------EAGPP---------- 140
Query: 497 QCPTLHFLEGGEDSDSDSEEEDDEEEDDEDEDDDDDEEDGDEV 539
EG E+ + + EEED++E++DEDE + E +EV
Sbjct: 141 --------EGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEV 175
Score = 40.8 bits (94), Expect = 0.004
Identities = 19/40 (47%), Positives = 27/40 (67%), Gaps = 2/40 (5%)
Query: 503 FLEGGEDSDSDSEEEDDEEEDDEDEDDDDDEEDGDEVPVP 542
+L+G + D+ E D EEEDDED D+DD+EE+ +E P
Sbjct: 103 YLDGFDQEDN--EAPDSEEEDDEDGDEDDEEEEENEAGPP 140
>gi|210147571 acidic (leucine-rich) nuclear phosphoprotein 32
family, member E isoform 3 [Homo sapiens]
Length = 220
Score = 75.9 bits (185), Expect = 1e-13
Identities = 56/148 (37%), Positives = 76/148 (51%), Gaps = 34/148 (22%)
Query: 399 TSLKSEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDE 458
T L +E+ E + EEE++ +G+E++E EEEE E G E G EEE EEE + D DE
Sbjct: 95 TYLDGFDQEDNEAPDSEEEDDEDGDEDDE--EEEENEAGPPE--GYEEEEEEEEEEDEDE 150
Query: 459 EEEEDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHFLEGGEDSDSDSEEED 518
+E+EDE S G +G E G S Y +EE Q E+ D D EE
Sbjct: 151 DEDEDEAGSELG-------EGEEEVGLS---YLMKEEIQ---------DEEDDDDYVEEG 191
Query: 519 DEEEDDE-----------DEDDDDDEED 535
+EEE++E D +DD +EED
Sbjct: 192 EEEEEEEEGGLRGEKRKRDAEDDGEEED 219
Score = 75.1 bits (183), Expect = 2e-13
Identities = 52/144 (36%), Positives = 75/144 (52%), Gaps = 33/144 (22%)
Query: 404 EGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEEEED 463
+G ++E+ E + EEE + + +E++ EEEE E G E G EEE EEE + D DE+E+ED
Sbjct: 98 DGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPE--GYEEEEEEEEEEDEDEDEDED 155
Query: 464 EESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHFLEGGEDSDSDSEEEDDEEED 523
E S G +G E G S Y +EE Q E+ D D EE +EEE+
Sbjct: 156 EAGSELG-------EGEEEVGLS---YLMKEEIQ---------DEEDDDDYVEEGEEEEE 196
Query: 524 DED------------EDDDDDEED 535
+E+ EDD ++E+D
Sbjct: 197 EEEGGLRGEKRKRDAEDDGEEEDD 220
Score = 46.2 bits (108), Expect = 9e-05
Identities = 32/103 (31%), Positives = 47/103 (45%), Gaps = 33/103 (32%)
Query: 437 GEGEELGEEEEVEEEGDVDSDEEEEEDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEA 496
G +E E + EEE D D DE++EE+EE+ EAG
Sbjct: 99 GFDQEDNEAPDSEEEDDEDGDEDDEEEEEN---------------EAGPP---------- 133
Query: 497 QCPTLHFLEGGEDSDSDSEEEDDEEEDDEDEDDDDDEEDGDEV 539
EG E+ + + EEED++E++DEDE + E +EV
Sbjct: 134 --------EGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEV 168
Score = 40.8 bits (94), Expect = 0.004
Identities = 19/40 (47%), Positives = 27/40 (67%), Gaps = 2/40 (5%)
Query: 503 FLEGGEDSDSDSEEEDDEEEDDEDEDDDDDEEDGDEVPVP 542
+L+G + D+ E D EEEDDED D+DD+EE+ +E P
Sbjct: 96 YLDGFDQEDN--EAPDSEEEDDEDGDEDDEEEEENEAGPP 133
>gi|28274705 family with sequence similarity 9, member A [Homo
sapiens]
Length = 332
Score = 74.7 bits (182), Expect = 2e-13
Identities = 48/103 (46%), Positives = 59/103 (57%), Gaps = 5/103 (4%)
Query: 376 EPSDIAACFREAGFGGGPNATITTSLKSEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEE 435
E ++ AA EA A + E EEEEE+EEEEE+EE E E EEE G EE EE
Sbjct: 192 EEAEAAAAAAEAAAAAEAAAAAAEVIVVEDEEEEEKEEEEEKEEEEEEGEEEGGGEEGEE 251
Query: 436 GGEGEELGEEEEVEEEGDVDSDEEEEEDEESSSEGLEAEDWAQ 478
GG G E GEE E EEE +EEEEE+E+ + + + W Q
Sbjct: 252 GGGGGE-GEETEEEEE----EEEEEEEEEQIKAFQEKQKRWQQ 289
Score = 51.6 bits (122), Expect = 2e-06
Identities = 35/120 (29%), Positives = 55/120 (45%), Gaps = 29/120 (24%)
Query: 410 EEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEEL--GEEEEVEEEGDVDSDEEEEEDEESS 467
E+++++E EE E E E E+ E+EE EE+ + + EEEEE+ E
Sbjct: 184 EKQKDDEAEEAEAAAAAAEAAAAAEAAAAAAEVIVVEDEEEEEKEEEEEKEEEEEEGEEE 243
Query: 468 SEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHFLEGGEDSDSDSEEEDDEEEDDEDE 527
G E E E GG GGE +++ EEE++EEE++E++
Sbjct: 244 GGGEEGE-------EGGG--------------------GGEGEETEEEEEEEEEEEEEEQ 276
Score = 37.0 bits (84), Expect = 0.052
Identities = 25/66 (37%), Positives = 33/66 (50%), Gaps = 8/66 (12%)
Query: 386 EAGFGGGPNATITTSLKSEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEE 445
E G GGG E EEEEEEEEEEEEEE +E++ ++ G L E
Sbjct: 250 EEGGGGGEG--------EETEEEEEEEEEEEEEEQIKAFQEKQKRWQQPTGVRSWRLREM 301
Query: 446 EEVEEE 451
+ + E+
Sbjct: 302 KPLLEQ 307
Score = 34.3 bits (77), Expect = 0.34
Identities = 20/79 (25%), Positives = 37/79 (46%), Gaps = 9/79 (11%)
Query: 458 EEEEEDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHFLEGGEDSDSDSEEE 517
E++++DE +E A A EA + E+ E E+ + + E+E
Sbjct: 184 EKQKDDEAEEAEAAAAAAEAAAAAEAAAAAAEVIVVED---------EEEEEKEEEEEKE 234
Query: 518 DDEEEDDEDEDDDDDEEDG 536
++EEE +E+ ++ EE G
Sbjct: 235 EEEEEGEEEGGGEEGEEGG 253
Score = 33.9 bits (76), Expect = 0.44
Identities = 23/104 (22%), Positives = 47/104 (45%), Gaps = 24/104 (23%)
Query: 458 EEEEEDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHFLEGGEDSDSDSEEE 517
++E E+ E+++ EA A+ A +EE E E+ + + EEE
Sbjct: 188 DDEAEEAEAAAAAAEAAAAAEAAAAAAEVIVVEDEEEE---------EKEEEEEKEEEEE 238
Query: 518 DDEEE---------------DDEDEDDDDDEEDGDEVPVPSFGE 546
+ EEE ++ +E+++++EE+ +E + +F E
Sbjct: 239 EGEEEGGGEEGEEGGGGGEGEETEEEEEEEEEEEEEEQIKAFQE 282
>gi|17975763 myelin transcription factor 1 [Homo sapiens]
Length = 1121
Score = 74.3 bits (181), Expect = 3e-13
Identities = 47/137 (34%), Positives = 69/137 (50%), Gaps = 8/137 (5%)
Query: 394 NATITTSLKSEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGD 453
+A S K +G EEE+EEEEEE E EEE+EE EEEEEE EEEE EEE +
Sbjct: 242 DAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEE-------EEEEEEEEEEE 294
Query: 454 VDSDEEEEEDEESSSEGLEAEDWAQGVVEAGGSF-GAYGAQEEAQCPTLHFLEGGEDSDS 512
+ +EEEEE+EE++ + + ED + + G + + + + +D D
Sbjct: 295 EEEEEEEEEEEEAAPDVIFQEDTSHTSAQKAPELRGPESPSPKPEYSVIVEVRSDDDKDE 354
Query: 513 DSEEEDDEEEDDEDEDD 529
D+ D+ + D
Sbjct: 355 DTHSRKSTVTDESEMQD 371
Score = 56.2 bits (134), Expect = 8e-08
Identities = 49/212 (23%), Positives = 88/212 (41%), Gaps = 41/212 (19%)
Query: 333 VKGHYRQAMLLKAMAALEGQDPSGLQLGLTEALHFVAAAWQAVEPSDIAACFREAGFGGG 392
VK H+ + A A+ +G S + T L+ A + + D+ + G
Sbjct: 137 VKSHFGSNPIGSATASSKGSYSSYQGIIATSLLNLGQIAEETLVEEDLGQAAKP-----G 191
Query: 393 PNATITTSLKSEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEE--GGEGEELGEEEEVEE 450
P +EG EE E+ + + EE E E ++ E+ EE ++
Sbjct: 192 PGIVHLLQEAAEGAASEEGEKGLFIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQ 251
Query: 451 EGDVDSDEEEEEDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHFLEGGEDS 510
+G + +EE+EE+EE E E ED E+
Sbjct: 252 KGILSHEEEDEEEEEEEEE--EEED--------------------------------EEE 277
Query: 511 DSDSEEEDDEEEDDEDEDDDDDEEDGDEVPVP 542
+ + EEE++EEE++E+E+++++EE+ +E P
Sbjct: 278 EEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAP 309
Score = 33.5 bits (75), Expect = 0.57
Identities = 23/83 (27%), Positives = 37/83 (44%)
Query: 402 KSEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEEE 461
+ E EEEEEEEEE + E+ ++ E E + E +V SD++++
Sbjct: 294 EEEEEEEEEEEEEAAPDVIFQEDTSHTSAQKAPELRGPESPSPKPEYSVIVEVRSDDDKD 353
Query: 462 EDEESSSEGLEAEDWAQGVVEAG 484
ED S + E Q ++ G
Sbjct: 354 EDTHSRKSTVTDESEMQDMMTRG 376
>gi|5454088 acidic (leucine-rich) nuclear phosphoprotein 32 family,
member B [Homo sapiens]
Length = 251
Score = 74.3 bits (181), Expect = 3e-13
Identities = 46/132 (34%), Positives = 67/132 (50%), Gaps = 27/132 (20%)
Query: 404 EGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEEEED 463
+G + E++E + + E +G +EEEE EE E+E E +E GEEEE +EE D D D E +ED
Sbjct: 146 DGYDREDQEAPDSDAEVDGVDEEEEDEEGEDEEDEDDEDGEEEEFDEEDDEDEDVEGDED 205
Query: 464 EESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHFLEGGEDSDSDSEEEDDEEED 523
++ SE E E+ +G EE ED D D EEE+ + +
Sbjct: 206 DDEVSE--EEEE--------------FGLDEE-----------DEDEDEDEEEEEGGKGE 238
Query: 524 DEDEDDDDDEED 535
+ DD+ ED
Sbjct: 239 KRKRETDDEGED 250
Score = 60.5 bits (145), Expect = 4e-09
Identities = 34/79 (43%), Positives = 49/79 (62%), Gaps = 5/79 (6%)
Query: 402 KSEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGE-GEELGEEEEV----EEEGDVDS 456
+ E EE E+EE+E++E+ E E +EE+ E+E+ EG E +E+ EEEE EE+ D D
Sbjct: 168 EEEDEEGEDEEDEDDEDGEEEEFDEEDDEDEDVEGDEDDDEVSEEEEEFGLDEEDEDEDE 227
Query: 457 DEEEEEDEESSSEGLEAED 475
DEEEEE + E +D
Sbjct: 228 DEEEEEGGKGEKRKRETDD 246
Score = 48.1 bits (113), Expect = 2e-05
Identities = 34/102 (33%), Positives = 46/102 (45%), Gaps = 38/102 (37%)
Query: 438 EGEELGEEEEVEEEGDVDSDEEEEEDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQ 497
+G + ++E + + +VD +EEEEDEE E E ED
Sbjct: 146 DGYDREDQEAPDSDAEVDGVDEEEEDEEGEDE--EDED---------------------- 181
Query: 498 CPTLHFLEGGEDSDSDSEEEDDEEEDDEDEDDDDDEEDGDEV 539
D D EEE+ +EEDDEDED + DE+D DEV
Sbjct: 182 -------------DEDGEEEEFDEEDDEDEDVEGDEDD-DEV 209
Score = 39.7 bits (91), Expect = 0.008
Identities = 17/39 (43%), Positives = 29/39 (74%), Gaps = 1/39 (2%)
Query: 504 LEGGEDSDSDSEEEDDEEEDDED-EDDDDDEEDGDEVPV 541
++G ++ + D E ED+E+EDDED E+++ DEED ++ V
Sbjct: 162 VDGVDEEEEDEEGEDEEDEDDEDGEEEEFDEEDDEDEDV 200
Score = 35.4 bits (80), Expect = 0.15
Identities = 17/53 (32%), Positives = 32/53 (60%), Gaps = 5/53 (9%)
Query: 499 PTLHFLEG-----GEDSDSDSEEEDDEEEDDEDEDDDDDEEDGDEVPVPSFGE 546
P L +L+G E DSD+E + +EE++++E +D+++ED ++ F E
Sbjct: 140 PQLTYLDGYDREDQEAPDSDAEVDGVDEEEEDEEGEDEEDEDDEDGEEEEFDE 192
>gi|115529449 upstream binding transcription factor, RNA polymerase
I isoform b [Homo sapiens]
Length = 727
Score = 72.4 bits (176), Expect = 1e-12
Identities = 35/96 (36%), Positives = 61/96 (63%), Gaps = 8/96 (8%)
Query: 392 GPNATIT-TSLKSEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEE--- 447
GPN + T+L+S+ E EE++EE+E++E+ + EEE++E + E+GG+ E E+E
Sbjct: 624 GPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESED 683
Query: 448 ----VEEEGDVDSDEEEEEDEESSSEGLEAEDWAQG 479
E++ D D DE+++EDE++ SEG + + G
Sbjct: 684 GDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSG 719
Score = 62.0 bits (149), Expect = 2e-09
Identities = 32/104 (30%), Positives = 55/104 (52%), Gaps = 23/104 (22%)
Query: 444 EEEEVEEEGDVDSDEEEEEDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHF 503
EE++ E+E D D DEEEE+DE S E GG +++E+
Sbjct: 641 EEDDEEDEDDEDEDEEEEDDENGDSS------------EDGGDSSESSSEDES------- 681
Query: 504 LEGGEDSDSDSEEEDDEEEDDEDEDDDDDEEDGDEVPVPSFGEA 547
ED D + E+++DE++D++D++D+D+E +G S G++
Sbjct: 682 ----EDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDS 721
Score = 55.8 bits (133), Expect = 1e-07
Identities = 29/86 (33%), Positives = 51/86 (59%), Gaps = 11/86 (12%)
Query: 448 VEEEGDVDSDEEEEEDEESSSEGLEAEDWAQG-VVEAGGSFGAYGAQEEAQCPTLHFLEG 506
++ + + + D+EE+ED+E E E ED G E GG +++E+ E
Sbjct: 634 LQSKSESEEDDEEDEDDEDEDE--EEEDDENGDSSEDGGDSSESSSEDES--------ED 683
Query: 507 GEDSDSDSEEEDDEEEDDEDEDDDDD 532
G++++ D E+EDD+E+DDEDED++ +
Sbjct: 684 GDENEEDDEDEDDDEDDDEDEDNESE 709
Score = 42.7 bits (99), Expect = 0.001
Identities = 18/29 (62%), Positives = 27/29 (93%), Gaps = 1/29 (3%)
Query: 510 SDSDSEEEDDEEEDDEDED-DDDDEEDGD 537
S S+SEE+D+E+EDDEDED +++D+E+GD
Sbjct: 636 SKSESEEDDEEDEDDEDEDEEEEDDENGD 664
Score = 40.0 bits (92), Expect = 0.006
Identities = 15/48 (31%), Positives = 29/48 (60%)
Query: 491 GAQEEAQCPTLHFLEGGEDSDSDSEEEDDEEEDDEDEDDDDDEEDGDE 538
G ++ TL E+ D + E+++DE+E++ED+++ D EDG +
Sbjct: 624 GPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGD 671
Score = 37.7 bits (86), Expect = 0.030
Identities = 14/51 (27%), Positives = 29/51 (56%)
Query: 403 SEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGD 453
SE E E+ +E EE++E+ + +E+++E E+ E EG + + + +
Sbjct: 677 SEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 727
Score = 36.6 bits (83), Expect = 0.068
Identities = 19/56 (33%), Positives = 31/56 (55%), Gaps = 4/56 (7%)
Query: 403 SEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGD-VDSD 457
SE E+E E+ +E EE + +E+++E ++E+E + E G GD DSD
Sbjct: 673 SESSSEDESEDGDENEEDDEDEDDDEDDDEDE---DNESEGSSSSSSSSGDSSDSD 725
Score = 32.0 bits (71), Expect = 1.7
Identities = 14/42 (33%), Positives = 26/42 (61%), Gaps = 2/42 (4%)
Query: 390 GGGPNATITTSLKSEGEEEEE--EEEEEEEEEGEGEEEEEEG 429
GG + + + +G+E EE E+E+++E++ E E+ E EG
Sbjct: 669 GGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEG 710
Score = 30.0 bits (66), Expect = 6.3
Identities = 11/35 (31%), Positives = 21/35 (60%)
Query: 504 LEGGEDSDSDSEEEDDEEEDDEDEDDDDDEEDGDE 538
L G S + + E +++DE+D+DDE++ +E
Sbjct: 622 LRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEE 656
>gi|115529451 upstream binding transcription factor, RNA polymerase
I isoform b [Homo sapiens]
Length = 727
Score = 72.4 bits (176), Expect = 1e-12
Identities = 35/96 (36%), Positives = 61/96 (63%), Gaps = 8/96 (8%)
Query: 392 GPNATIT-TSLKSEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEE--- 447
GPN + T+L+S+ E EE++EE+E++E+ + EEE++E + E+GG+ E E+E
Sbjct: 624 GPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESED 683
Query: 448 ----VEEEGDVDSDEEEEEDEESSSEGLEAEDWAQG 479
E++ D D DE+++EDE++ SEG + + G
Sbjct: 684 GDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSG 719
Score = 62.0 bits (149), Expect = 2e-09
Identities = 32/104 (30%), Positives = 55/104 (52%), Gaps = 23/104 (22%)
Query: 444 EEEEVEEEGDVDSDEEEEEDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHF 503
EE++ E+E D D DEEEE+DE S E GG +++E+
Sbjct: 641 EEDDEEDEDDEDEDEEEEDDENGDSS------------EDGGDSSESSSEDES------- 681
Query: 504 LEGGEDSDSDSEEEDDEEEDDEDEDDDDDEEDGDEVPVPSFGEA 547
ED D + E+++DE++D++D++D+D+E +G S G++
Sbjct: 682 ----EDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDS 721
Score = 55.8 bits (133), Expect = 1e-07
Identities = 29/86 (33%), Positives = 51/86 (59%), Gaps = 11/86 (12%)
Query: 448 VEEEGDVDSDEEEEEDEESSSEGLEAEDWAQG-VVEAGGSFGAYGAQEEAQCPTLHFLEG 506
++ + + + D+EE+ED+E E E ED G E GG +++E+ E
Sbjct: 634 LQSKSESEEDDEEDEDDEDEDE--EEEDDENGDSSEDGGDSSESSSEDES--------ED 683
Query: 507 GEDSDSDSEEEDDEEEDDEDEDDDDD 532
G++++ D E+EDD+E+DDEDED++ +
Sbjct: 684 GDENEEDDEDEDDDEDDDEDEDNESE 709
Score = 42.7 bits (99), Expect = 0.001
Identities = 18/29 (62%), Positives = 27/29 (93%), Gaps = 1/29 (3%)
Query: 510 SDSDSEEEDDEEEDDEDED-DDDDEEDGD 537
S S+SEE+D+E+EDDEDED +++D+E+GD
Sbjct: 636 SKSESEEDDEEDEDDEDEDEEEEDDENGD 664
Score = 40.0 bits (92), Expect = 0.006
Identities = 15/48 (31%), Positives = 29/48 (60%)
Query: 491 GAQEEAQCPTLHFLEGGEDSDSDSEEEDDEEEDDEDEDDDDDEEDGDE 538
G ++ TL E+ D + E+++DE+E++ED+++ D EDG +
Sbjct: 624 GPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGD 671
Score = 37.7 bits (86), Expect = 0.030
Identities = 14/51 (27%), Positives = 29/51 (56%)
Query: 403 SEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGD 453
SE E E+ +E EE++E+ + +E+++E E+ E EG + + + +
Sbjct: 677 SEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 727
Score = 36.6 bits (83), Expect = 0.068
Identities = 19/56 (33%), Positives = 31/56 (55%), Gaps = 4/56 (7%)
Query: 403 SEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGD-VDSD 457
SE E+E E+ +E EE + +E+++E ++E+E + E G GD DSD
Sbjct: 673 SESSSEDESEDGDENEEDDEDEDDDEDDDEDE---DNESEGSSSSSSSSGDSSDSD 725
Score = 32.0 bits (71), Expect = 1.7
Identities = 14/42 (33%), Positives = 26/42 (61%), Gaps = 2/42 (4%)
Query: 390 GGGPNATITTSLKSEGEEEEE--EEEEEEEEEGEGEEEEEEG 429
GG + + + +G+E EE E+E+++E++ E E+ E EG
Sbjct: 669 GGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEG 710
Score = 30.0 bits (66), Expect = 6.3
Identities = 11/35 (31%), Positives = 21/35 (60%)
Query: 504 LEGGEDSDSDSEEEDDEEEDDEDEDDDDDEEDGDE 538
L G S + + E +++DE+D+DDE++ +E
Sbjct: 622 LRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEE 656
>gi|7657671 upstream binding transcription factor, RNA polymerase I
isoform a [Homo sapiens]
Length = 764
Score = 72.4 bits (176), Expect = 1e-12
Identities = 35/96 (36%), Positives = 61/96 (63%), Gaps = 8/96 (8%)
Query: 392 GPNATIT-TSLKSEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEE--- 447
GPN + T+L+S+ E EE++EE+E++E+ + EEE++E + E+GG+ E E+E
Sbjct: 661 GPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESED 720
Query: 448 ----VEEEGDVDSDEEEEEDEESSSEGLEAEDWAQG 479
E++ D D DE+++EDE++ SEG + + G
Sbjct: 721 GDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSG 756
Score = 62.0 bits (149), Expect = 2e-09
Identities = 32/104 (30%), Positives = 55/104 (52%), Gaps = 23/104 (22%)
Query: 444 EEEEVEEEGDVDSDEEEEEDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHF 503
EE++ E+E D D DEEEE+DE S E GG +++E+
Sbjct: 678 EEDDEEDEDDEDEDEEEEDDENGDSS------------EDGGDSSESSSEDES------- 718
Query: 504 LEGGEDSDSDSEEEDDEEEDDEDEDDDDDEEDGDEVPVPSFGEA 547
ED D + E+++DE++D++D++D+D+E +G S G++
Sbjct: 719 ----EDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDS 758
Score = 55.8 bits (133), Expect = 1e-07
Identities = 29/86 (33%), Positives = 51/86 (59%), Gaps = 11/86 (12%)
Query: 448 VEEEGDVDSDEEEEEDEESSSEGLEAEDWAQG-VVEAGGSFGAYGAQEEAQCPTLHFLEG 506
++ + + + D+EE+ED+E E E ED G E GG +++E+ E
Sbjct: 671 LQSKSESEEDDEEDEDDEDEDE--EEEDDENGDSSEDGGDSSESSSEDES--------ED 720
Query: 507 GEDSDSDSEEEDDEEEDDEDEDDDDD 532
G++++ D E+EDD+E+DDEDED++ +
Sbjct: 721 GDENEEDDEDEDDDEDDDEDEDNESE 746
Score = 42.7 bits (99), Expect = 0.001
Identities = 18/29 (62%), Positives = 27/29 (93%), Gaps = 1/29 (3%)
Query: 510 SDSDSEEEDDEEEDDEDED-DDDDEEDGD 537
S S+SEE+D+E+EDDEDED +++D+E+GD
Sbjct: 673 SKSESEEDDEEDEDDEDEDEEEEDDENGD 701
Score = 40.0 bits (92), Expect = 0.006
Identities = 15/48 (31%), Positives = 29/48 (60%)
Query: 491 GAQEEAQCPTLHFLEGGEDSDSDSEEEDDEEEDDEDEDDDDDEEDGDE 538
G ++ TL E+ D + E+++DE+E++ED+++ D EDG +
Sbjct: 661 GPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGD 708
Score = 37.7 bits (86), Expect = 0.030
Identities = 14/51 (27%), Positives = 29/51 (56%)
Query: 403 SEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGD 453
SE E E+ +E EE++E+ + +E+++E E+ E EG + + + +
Sbjct: 714 SEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 764
Score = 36.6 bits (83), Expect = 0.068
Identities = 19/56 (33%), Positives = 31/56 (55%), Gaps = 4/56 (7%)
Query: 403 SEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGD-VDSD 457
SE E+E E+ +E EE + +E+++E ++E+E + E G GD DSD
Sbjct: 710 SESSSEDESEDGDENEEDDEDEDDDEDDDEDE---DNESEGSSSSSSSSGDSSDSD 762
Score = 32.0 bits (71), Expect = 1.7
Identities = 14/42 (33%), Positives = 26/42 (61%), Gaps = 2/42 (4%)
Query: 390 GGGPNATITTSLKSEGEEEEE--EEEEEEEEEGEGEEEEEEG 429
GG + + + +G+E EE E+E+++E++ E E+ E EG
Sbjct: 706 GGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEG 747
Score = 30.0 bits (66), Expect = 6.3
Identities = 11/35 (31%), Positives = 21/35 (60%)
Query: 504 LEGGEDSDSDSEEEDDEEEDDEDEDDDDDEEDGDE 538
L G S + + E +++DE+D+DDE++ +E
Sbjct: 659 LRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEE 693
>gi|42476169 Paf1, RNA polymerase II associated factor, homolog
[Homo sapiens]
Length = 531
Score = 72.4 bits (176), Expect = 1e-12
Identities = 46/132 (34%), Positives = 59/132 (44%), Gaps = 28/132 (21%)
Query: 406 EEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEEEEDEE 465
EEEEEE E EE+E G +EE+E+G E+EG E E G E E EE D +E D+
Sbjct: 378 EEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHSGSESEREE-----GDRDEASDKS 432
Query: 466 SSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHFLEGGEDSDSDSEEEDDEEEDDE 525
S E +ED A+ + FG SD++ EDD + DDE
Sbjct: 433 GSGEDESSEDEARAARDKEEIFG-----------------------SDADSEDDADSDDE 469
Query: 526 DEDDDDDEEDGD 537
D D D
Sbjct: 470 DRGQAQGGSDND 481
Score = 46.2 bits (108), Expect = 9e-05
Identities = 37/150 (24%), Positives = 65/150 (43%), Gaps = 10/150 (6%)
Query: 385 REAGFGGGPNATITTSLKSEGEEEEE---EEEEEEEEEGEGEEEEEEGEEEEEEGGEGEE 441
+EAG G +S + EG E+E E E EE + E ++ GE+E E +E
Sbjct: 389 KEAG-GSDEEQEKGSSSEKEGSEDEHSGSESEREEGDRDEASDKSGSGEDESSE----DE 443
Query: 442 LGEEEEVEEEGDVDSDEEEEEDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTL 501
+ EE D+D E++ D + G +A+ + ++G + G ++ ++ +
Sbjct: 444 ARAARDKEEIFGSDADSEDDADSDDEDRG-QAQGGSDNDSDSGSNGGGQRSRSHSRSAS- 501
Query: 502 HFLEGGEDSDSDSEEEDDEEEDDEDEDDDD 531
F G E S + E + E + D D
Sbjct: 502 PFPSGSEHSAQEDGSEAAASDSSEADSDSD 531
Score = 44.3 bits (103), Expect = 3e-04
Identities = 43/154 (27%), Positives = 57/154 (37%), Gaps = 49/154 (31%)
Query: 386 EAGFGGGPNATITTSLKSEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEE 445
+AG G NA + + E+E E +E + + E E EEEEEE E
Sbjct: 338 KAGVQSGTNALLVVK-----HRDMNEKELEAQEARKAQLENHEPEEEEEE---------E 383
Query: 446 EEVEEEGDVDSDEEEEEDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHFLE 505
E EE+ SDEE+E+ S EG E
Sbjct: 384 METEEKEAGGSDEEQEKGSSSEKEGSE--------------------------------- 410
Query: 506 GGEDSDSDSE-EEDDEEEDDEDEDDDDDEEDGDE 538
E S S+SE EE D +E + +DE DE
Sbjct: 411 -DEHSGSESEREEGDRDEASDKSGSGEDESSEDE 443
>gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]
Length = 770
Score = 71.6 bits (174), Expect = 2e-12
Identities = 38/77 (49%), Positives = 48/77 (62%), Gaps = 4/77 (5%)
Query: 394 NATITTSLKSEGEEEEEEEEEEEEEEG----EGEEEEEEGEEEEEEGGEGEELGEEEEVE 449
+A +++ G EEEEEEEEEEEEEG E EEEEEE EEEEEE G E E+ E
Sbjct: 266 SAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAE 325
Query: 450 EEGDVDSDEEEEEDEES 466
E + + E+EE + E+
Sbjct: 326 EVSEEEMSEDEERENEN 342
Score = 68.9 bits (167), Expect = 1e-11
Identities = 50/139 (35%), Positives = 64/139 (46%), Gaps = 14/139 (10%)
Query: 403 SEGEEEEEEEEEEEEEEGEG-EEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEEE 461
S+ E + E E G G EEEEEE EEEEEEG EE EEEE EEE + ++ E
Sbjct: 258 SDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSE 317
Query: 462 EDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHFLEGGEDSDSDSEEEDDEE 521
E E S+E + E+ ++ + E + L E D DS E E+ EE
Sbjct: 318 EASEQSAEEVSEEEMSE------------DEERENENHLLVVPESRFDRDS-GESEEAEE 364
Query: 522 EDDEDEDDDDDEEDGDEVP 540
E E +GD VP
Sbjct: 365 EVGEGTPQSSALTEGDYVP 383
Score = 67.4 bits (163), Expect = 4e-11
Identities = 40/99 (40%), Positives = 53/99 (53%), Gaps = 2/99 (2%)
Query: 373 QAVEPSDIAACFREAGFGGGPNATITTSLKSEGEEEEEEEEEEEEEEGEGEEEEEEGEEE 432
+ +E D+ + ++ ++ +S G EEEEEEEEEEE EG EE EEE
Sbjct: 243 EKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEE 302
Query: 433 EEEGGEGEELG--EEEEVEEEGDVDSDEEEEEDEESSSE 469
EEE E EE G EE E+ + S+EE EDEE +E
Sbjct: 303 EEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENE 341
Score = 48.1 bits (113), Expect = 2e-05
Identities = 38/164 (23%), Positives = 67/164 (40%), Gaps = 24/164 (14%)
Query: 407 EEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEE------------------EEV 448
E+++E+ E++E E EE +E E E + E+ E
Sbjct: 171 EQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRER 230
Query: 449 EEEGD----VDSDEEEEEDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHFL 504
E GD V ++ EE D S + + + E+ + G++EE +
Sbjct: 231 FELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEE 290
Query: 505 EGG--EDSDSDSEEEDDEEEDDEDEDDDDDEEDGDEVPVPSFGE 546
EG E+S+ + EEE++EEE+ ++ E+ +EV E
Sbjct: 291 EGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSE 334
Score = 43.9 bits (102), Expect = 4e-04
Identities = 33/81 (40%), Positives = 39/81 (48%), Gaps = 18/81 (22%)
Query: 395 ATITTSLKSEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEG-- 452
+T S + E EEEEEEEE G EE E+ EE E EE+ E+EE E E
Sbjct: 293 STSEESEEEEEEEEEEEEE-------TGSNSEEASEQSAEEVSE-EEMSEDEERENENHL 344
Query: 453 --------DVDSDEEEEEDEE 465
D DS E EE +EE
Sbjct: 345 LVVPESRFDRDSGESEEAEEE 365
Score = 34.7 bits (78), Expect = 0.26
Identities = 37/180 (20%), Positives = 65/180 (36%), Gaps = 47/180 (26%)
Query: 406 EEEEEEEE--------------------------EEEEEEGEGEEEEEEGEEEEEEGGEG 439
+ EE++ E+ E + E E + E ++E+ E E
Sbjct: 123 KRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKER 182
Query: 440 EELGEEEEVEEEGDVDSDEEEEEDEESSSEGLEAEDWAQGV-------VEAGGSFGAYGA 492
E EE E E + E S+ ++A W++ E G
Sbjct: 183 ERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKE 242
Query: 493 QEEAQCPTLHFLEGGEDSD--------------SDSEEEDDEEEDDEDEDDDDDEEDGDE 538
++ + L L+ DS+ S SEEE++EEE++E+E +E + +E
Sbjct: 243 EKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEE 302
>gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]
Length = 780
Score = 71.6 bits (174), Expect = 2e-12
Identities = 38/77 (49%), Positives = 48/77 (62%), Gaps = 4/77 (5%)
Query: 394 NATITTSLKSEGEEEEEEEEEEEEEEG----EGEEEEEEGEEEEEEGGEGEELGEEEEVE 449
+A +++ G EEEEEEEEEEEEEG E EEEEEE EEEEEE G E E+ E
Sbjct: 276 SAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAE 335
Query: 450 EEGDVDSDEEEEEDEES 466
E + + E+EE + E+
Sbjct: 336 EVSEEEMSEDEERENEN 352
Score = 68.9 bits (167), Expect = 1e-11
Identities = 50/139 (35%), Positives = 64/139 (46%), Gaps = 14/139 (10%)
Query: 403 SEGEEEEEEEEEEEEEEGEG-EEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEEE 461
S+ E + E E G G EEEEEE EEEEEEG EE EEEE EEE + ++ E
Sbjct: 268 SDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSE 327
Query: 462 EDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHFLEGGEDSDSDSEEEDDEE 521
E E S+E + E+ ++ + E + L E D DS E E+ EE
Sbjct: 328 EASEQSAEEVSEEEMSE------------DEERENENHLLVVPESRFDRDS-GESEEAEE 374
Query: 522 EDDEDEDDDDDEEDGDEVP 540
E E +GD VP
Sbjct: 375 EVGEGTPQSSALTEGDYVP 393
Score = 67.4 bits (163), Expect = 4e-11
Identities = 40/99 (40%), Positives = 53/99 (53%), Gaps = 2/99 (2%)
Query: 373 QAVEPSDIAACFREAGFGGGPNATITTSLKSEGEEEEEEEEEEEEEEGEGEEEEEEGEEE 432
+ +E D+ + ++ ++ +S G EEEEEEEEEEE EG EE EEE
Sbjct: 253 EKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEE 312
Query: 433 EEEGGEGEELG--EEEEVEEEGDVDSDEEEEEDEESSSE 469
EEE E EE G EE E+ + S+EE EDEE +E
Sbjct: 313 EEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENE 351
Score = 48.1 bits (113), Expect = 2e-05
Identities = 38/164 (23%), Positives = 67/164 (40%), Gaps = 24/164 (14%)
Query: 407 EEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEE------------------EEV 448
E+++E+ E++E E EE +E E E + E+ E
Sbjct: 181 EQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRER 240
Query: 449 EEEGD----VDSDEEEEEDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHFL 504
E GD V ++ EE D S + + + E+ + G++EE +
Sbjct: 241 FELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEE 300
Query: 505 EGG--EDSDSDSEEEDDEEEDDEDEDDDDDEEDGDEVPVPSFGE 546
EG E+S+ + EEE++EEE+ ++ E+ +EV E
Sbjct: 301 EGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSE 344
Score = 43.9 bits (102), Expect = 4e-04
Identities = 33/81 (40%), Positives = 39/81 (48%), Gaps = 18/81 (22%)
Query: 395 ATITTSLKSEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEG-- 452
+T S + E EEEEEEEE G EE E+ EE E EE+ E+EE E E
Sbjct: 303 STSEESEEEEEEEEEEEEE-------TGSNSEEASEQSAEEVSE-EEMSEDEERENENHL 354
Query: 453 --------DVDSDEEEEEDEE 465
D DS E EE +EE
Sbjct: 355 LVVPESRFDRDSGESEEAEEE 375
Score = 38.1 bits (87), Expect = 0.023
Identities = 40/195 (20%), Positives = 70/195 (35%), Gaps = 47/195 (24%)
Query: 391 GGPNATITTSLKSEGEEEEEEEE--------------------------EEEEEEGEGEE 424
GG +A + + EE++ E+ E + E E
Sbjct: 118 GGKHARVKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERER 177
Query: 425 EEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEEEEDEESSSEGLEAEDWAQGV---- 480
+ E ++E+ E E E EE E E + E S+ ++A W++
Sbjct: 178 KMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPP 237
Query: 481 ---VEAGGSFGAYGAQEEAQCPTLHFLEGGEDSD--------------SDSEEEDDEEED 523
E G ++ + L L+ DS+ S SEEE++EEE+
Sbjct: 238 RERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEE 297
Query: 524 DEDEDDDDDEEDGDE 538
+E+E +E + +E
Sbjct: 298 EEEEGSTSEESEEEE 312
>gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform
9 [Homo sapiens]
Length = 771
Score = 71.6 bits (174), Expect = 2e-12
Identities = 38/77 (49%), Positives = 48/77 (62%), Gaps = 4/77 (5%)
Query: 394 NATITTSLKSEGEEEEEEEEEEEEEEG----EGEEEEEEGEEEEEEGGEGEELGEEEEVE 449
+A +++ G EEEEEEEEEEEEEG E EEEEEE EEEEEE G E E+ E
Sbjct: 267 SAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAE 326
Query: 450 EEGDVDSDEEEEEDEES 466
E + + E+EE + E+
Sbjct: 327 EVSEEEMSEDEERENEN 343
Score = 68.9 bits (167), Expect = 1e-11
Identities = 50/139 (35%), Positives = 64/139 (46%), Gaps = 14/139 (10%)
Query: 403 SEGEEEEEEEEEEEEEEGEG-EEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEEE 461
S+ E + E E G G EEEEEE EEEEEEG EE EEEE EEE + ++ E
Sbjct: 259 SDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSE 318
Query: 462 EDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHFLEGGEDSDSDSEEEDDEE 521
E E S+E + E+ ++ + E + L E D DS E E+ EE
Sbjct: 319 EASEQSAEEVSEEEMSE------------DEERENENHLLVVPESRFDRDS-GESEEAEE 365
Query: 522 EDDEDEDDDDDEEDGDEVP 540
E E +GD VP
Sbjct: 366 EVGEGTPQSSALTEGDYVP 384
Score = 67.4 bits (163), Expect = 4e-11
Identities = 40/99 (40%), Positives = 53/99 (53%), Gaps = 2/99 (2%)
Query: 373 QAVEPSDIAACFREAGFGGGPNATITTSLKSEGEEEEEEEEEEEEEEGEGEEEEEEGEEE 432
+ +E D+ + ++ ++ +S G EEEEEEEEEEE EG EE EEE
Sbjct: 244 EKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEE 303
Query: 433 EEEGGEGEELG--EEEEVEEEGDVDSDEEEEEDEESSSE 469
EEE E EE G EE E+ + S+EE EDEE +E
Sbjct: 304 EEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENE 342
Score = 48.1 bits (113), Expect = 2e-05
Identities = 38/164 (23%), Positives = 67/164 (40%), Gaps = 24/164 (14%)
Query: 407 EEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEE------------------EEV 448
E+++E+ E++E E EE +E E E + E+ E
Sbjct: 172 EQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRER 231
Query: 449 EEEGD----VDSDEEEEEDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHFL 504
E GD V ++ EE D S + + + E+ + G++EE +
Sbjct: 232 FELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEE 291
Query: 505 EGG--EDSDSDSEEEDDEEEDDEDEDDDDDEEDGDEVPVPSFGE 546
EG E+S+ + EEE++EEE+ ++ E+ +EV E
Sbjct: 292 EGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSE 335
Score = 43.9 bits (102), Expect = 4e-04
Identities = 33/81 (40%), Positives = 39/81 (48%), Gaps = 18/81 (22%)
Query: 395 ATITTSLKSEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEG-- 452
+T S + E EEEEEEEE G EE E+ EE E EE+ E+EE E E
Sbjct: 294 STSEESEEEEEEEEEEEEE-------TGSNSEEASEQSAEEVSE-EEMSEDEERENENHL 345
Query: 453 --------DVDSDEEEEEDEE 465
D DS E EE +EE
Sbjct: 346 LVVPESRFDRDSGESEEAEEE 366
Score = 34.7 bits (78), Expect = 0.26
Identities = 37/180 (20%), Positives = 65/180 (36%), Gaps = 47/180 (26%)
Query: 406 EEEEEEEE--------------------------EEEEEEGEGEEEEEEGEEEEEEGGEG 439
+ EE++ E+ E + E E + E ++E+ E E
Sbjct: 124 KRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKER 183
Query: 440 EELGEEEEVEEEGDVDSDEEEEEDEESSSEGLEAEDWAQGV-------VEAGGSFGAYGA 492
E EE E E + E S+ ++A W++ E G
Sbjct: 184 ERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKE 243
Query: 493 QEEAQCPTLHFLEGGEDSD--------------SDSEEEDDEEEDDEDEDDDDDEEDGDE 538
++ + L L+ DS+ S SEEE++EEE++E+E +E + +E
Sbjct: 244 EKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEE 303
Score = 30.4 bits (67), Expect = 4.9
Identities = 31/99 (31%), Positives = 38/99 (38%), Gaps = 6/99 (6%)
Query: 403 SEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEE---EGDVDSDEE 459
SE EE EEE E+E E E E E + GE EE EE EG S
Sbjct: 321 SEQSAEEVSEEEMSEDE---ERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSAL 377
Query: 460 EEEDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQC 498
E D S L + Q + + + + EE QC
Sbjct: 378 TEGDYVPDSPALSPIELKQELPKYLPALQGCRSVEEFQC 416
>gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isoform
8 [Homo sapiens]
Length = 780
Score = 71.6 bits (174), Expect = 2e-12
Identities = 38/77 (49%), Positives = 48/77 (62%), Gaps = 4/77 (5%)
Query: 394 NATITTSLKSEGEEEEEEEEEEEEEEG----EGEEEEEEGEEEEEEGGEGEELGEEEEVE 449
+A +++ G EEEEEEEEEEEEEG E EEEEEE EEEEEE G E E+ E
Sbjct: 276 SAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAE 335
Query: 450 EEGDVDSDEEEEEDEES 466
E + + E+EE + E+
Sbjct: 336 EVSEEEMSEDEERENEN 352
Score = 68.9 bits (167), Expect = 1e-11
Identities = 50/139 (35%), Positives = 64/139 (46%), Gaps = 14/139 (10%)
Query: 403 SEGEEEEEEEEEEEEEEGEG-EEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEEE 461
S+ E + E E G G EEEEEE EEEEEEG EE EEEE EEE + ++ E
Sbjct: 268 SDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSE 327
Query: 462 EDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHFLEGGEDSDSDSEEEDDEE 521
E E S+E + E+ ++ + E + L E D DS E E+ EE
Sbjct: 328 EASEQSAEEVSEEEMSE------------DEERENENHLLVVPESRFDRDS-GESEEAEE 374
Query: 522 EDDEDEDDDDDEEDGDEVP 540
E E +GD VP
Sbjct: 375 EVGEGTPQSSALTEGDYVP 393
Score = 67.4 bits (163), Expect = 4e-11
Identities = 40/99 (40%), Positives = 53/99 (53%), Gaps = 2/99 (2%)
Query: 373 QAVEPSDIAACFREAGFGGGPNATITTSLKSEGEEEEEEEEEEEEEEGEGEEEEEEGEEE 432
+ +E D+ + ++ ++ +S G EEEEEEEEEEE EG EE EEE
Sbjct: 253 EKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEE 312
Query: 433 EEEGGEGEELG--EEEEVEEEGDVDSDEEEEEDEESSSE 469
EEE E EE G EE E+ + S+EE EDEE +E
Sbjct: 313 EEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENE 351
Score = 48.1 bits (113), Expect = 2e-05
Identities = 38/164 (23%), Positives = 67/164 (40%), Gaps = 24/164 (14%)
Query: 407 EEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEE------------------EEV 448
E+++E+ E++E E EE +E E E + E+ E
Sbjct: 181 EQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRER 240
Query: 449 EEEGD----VDSDEEEEEDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHFL 504
E GD V ++ EE D S + + + E+ + G++EE +
Sbjct: 241 FELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEE 300
Query: 505 EGG--EDSDSDSEEEDDEEEDDEDEDDDDDEEDGDEVPVPSFGE 546
EG E+S+ + EEE++EEE+ ++ E+ +EV E
Sbjct: 301 EGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSE 344
Score = 43.9 bits (102), Expect = 4e-04
Identities = 33/81 (40%), Positives = 39/81 (48%), Gaps = 18/81 (22%)
Query: 395 ATITTSLKSEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEG-- 452
+T S + E EEEEEEEE G EE E+ EE E EE+ E+EE E E
Sbjct: 303 STSEESEEEEEEEEEEEEE-------TGSNSEEASEQSAEEVSE-EEMSEDEERENENHL 354
Query: 453 --------DVDSDEEEEEDEE 465
D DS E EE +EE
Sbjct: 355 LVVPESRFDRDSGESEEAEEE 375
Score = 30.4 bits (67), Expect = 4.9
Identities = 31/99 (31%), Positives = 38/99 (38%), Gaps = 6/99 (6%)
Query: 403 SEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEE---EGDVDSDEE 459
SE EE EEE E+E E E E E + GE EE EE EG S
Sbjct: 330 SEQSAEEVSEEEMSEDE---ERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSAL 386
Query: 460 EEEDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQC 498
E D S L + Q + + + + EE QC
Sbjct: 387 TEGDYVPDSPALSPIELKQELPKYLPALQGCRSVEEFQC 425
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.130 0.370
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,747,228
Number of Sequences: 37866
Number of extensions: 1585896
Number of successful extensions: 107807
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1393
Number of HSP's successfully gapped in prelim test: 581
Number of HSP's that attempted gapping in prelim test: 19781
Number of HSP's gapped (non-prelim): 31779
length of query: 599
length of database: 18,247,518
effective HSP length: 108
effective length of query: 491
effective length of database: 14,157,990
effective search space: 6951573090
effective search space used: 6951573090
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.