Guide to the Human Genome
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Search of human proteins with 21735415

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|21735415 centromere protein B [Homo sapiens]
         (599 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|21735415 centromere protein B [Homo sapiens]                      1196   0.0  
gi|13569924 hypothetical protein LOC81789 [Homo sapiens]              202   5e-52
gi|22219477 tigger transposable element derived 4 [Homo sapiens]      184   2e-46
gi|23312394 tigger transposable element derived 3 [Homo sapiens]      145   1e-34
gi|23312392 tigger transposable element derived 2 [Homo sapiens]      136   5e-32
gi|22547224 jerky homolog-like [Homo sapiens]                         117   3e-26
gi|144922631 tigger transposable element derived 5 [Homo sapiens]     114   3e-25
gi|22325392 tigger transposable element derived 7 [Homo sapiens]      112   1e-24
gi|117938293 jerky isoform a [Homo sapiens]                           108   1e-23
gi|117938295 jerky isoform b [Homo sapiens]                           108   1e-23
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom...   103   5e-22
gi|22209001 hypothetical protein LOC200765 [Homo sapiens]              95   2e-19
gi|55956788 nucleolin [Homo sapiens]                                   87   3e-17
gi|4759128 solute carrier family 24 (sodium/potassium/calcium ex...    84   3e-16
gi|155030232 proline, glutamic acid and leucine rich protein 1 [...    82   1e-15
gi|13540523 nucleosomal binding protein 1 [Homo sapiens]               79   1e-14
gi|13569879 acidic (leucine-rich) nuclear phosphoprotein 32 fami...    76   1e-13
gi|210147569 acidic (leucine-rich) nuclear phosphoprotein 32 fam...    76   1e-13
gi|210147571 acidic (leucine-rich) nuclear phosphoprotein 32 fam...    76   1e-13
gi|28274705 family with sequence similarity 9, member A [Homo sa...    75   2e-13
gi|17975763 myelin transcription factor 1 [Homo sapiens]               74   3e-13
gi|5454088 acidic (leucine-rich) nuclear phosphoprotein 32 famil...    74   3e-13
gi|115529449 upstream binding transcription factor, RNA polymera...    72   1e-12
gi|115529451 upstream binding transcription factor, RNA polymera...    72   1e-12
gi|7657671 upstream binding transcription factor, RNA polymerase...    72   1e-12
gi|42476169 Paf1, RNA polymerase II associated factor, homolog [...    72   1e-12
gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]     72   2e-12
gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]     72   2e-12
gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof...    72   2e-12
gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isof...    72   2e-12

>gi|21735415 centromere protein B [Homo sapiens]
          Length = 599

 Score = 1196 bits (3093), Expect = 0.0
 Identities = 599/599 (100%), Positives = 599/599 (100%)

Query: 1   MGPKRRQLTFREKSRIIQEVEENPDLRKGEIARRFNIPPSTLSTILKNKRAILASERKYG 60
           MGPKRRQLTFREKSRIIQEVEENPDLRKGEIARRFNIPPSTLSTILKNKRAILASERKYG
Sbjct: 1   MGPKRRQLTFREKSRIIQEVEENPDLRKGEIARRFNIPPSTLSTILKNKRAILASERKYG 60

Query: 61  VASTCRKTNKLSPYDKLEGLLIAWFQQIRAAGLPVKGIILKEKALRIAEELGMDDFTASN 120
           VASTCRKTNKLSPYDKLEGLLIAWFQQIRAAGLPVKGIILKEKALRIAEELGMDDFTASN
Sbjct: 61  VASTCRKTNKLSPYDKLEGLLIAWFQQIRAAGLPVKGIILKEKALRIAEELGMDDFTASN 120

Query: 121 GWLDRFRRRHGVVSCSGVARARARNAAPRTPAAPASPAAVPSEGSGGSTTGWRAREEQPP 180
           GWLDRFRRRHGVVSCSGVARARARNAAPRTPAAPASPAAVPSEGSGGSTTGWRAREEQPP
Sbjct: 121 GWLDRFRRRHGVVSCSGVARARARNAAPRTPAAPASPAAVPSEGSGGSTTGWRAREEQPP 180

Query: 181 SVAEGYASQDVFSATETSLWYDFLPDQAAGLCGGDGRPRQATQRLSVLLCANADGSEKLP 240
           SVAEGYASQDVFSATETSLWYDFLPDQAAGLCGGDGRPRQATQRLSVLLCANADGSEKLP
Sbjct: 181 SVAEGYASQDVFSATETSLWYDFLPDQAAGLCGGDGRPRQATQRLSVLLCANADGSEKLP 240

Query: 241 PLVAGKSAKPRAGQAGLPCDYTANSKGGVTTQALAKYLKALDTRMAAESRRVLLLAGRLA 300
           PLVAGKSAKPRAGQAGLPCDYTANSKGGVTTQALAKYLKALDTRMAAESRRVLLLAGRLA
Sbjct: 241 PLVAGKSAKPRAGQAGLPCDYTANSKGGVTTQALAKYLKALDTRMAAESRRVLLLAGRLA 300

Query: 301 AQSLDTSGLRHVQLAFFPPGTVHPLERGVVQQVKGHYRQAMLLKAMAALEGQDPSGLQLG 360
           AQSLDTSGLRHVQLAFFPPGTVHPLERGVVQQVKGHYRQAMLLKAMAALEGQDPSGLQLG
Sbjct: 301 AQSLDTSGLRHVQLAFFPPGTVHPLERGVVQQVKGHYRQAMLLKAMAALEGQDPSGLQLG 360

Query: 361 LTEALHFVAAAWQAVEPSDIAACFREAGFGGGPNATITTSLKSEGEEEEEEEEEEEEEEG 420
           LTEALHFVAAAWQAVEPSDIAACFREAGFGGGPNATITTSLKSEGEEEEEEEEEEEEEEG
Sbjct: 361 LTEALHFVAAAWQAVEPSDIAACFREAGFGGGPNATITTSLKSEGEEEEEEEEEEEEEEG 420

Query: 421 EGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEEEEDEESSSEGLEAEDWAQGV 480
           EGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEEEEDEESSSEGLEAEDWAQGV
Sbjct: 421 EGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEEEEDEESSSEGLEAEDWAQGV 480

Query: 481 VEAGGSFGAYGAQEEAQCPTLHFLEGGEDSDSDSEEEDDEEEDDEDEDDDDDEEDGDEVP 540
           VEAGGSFGAYGAQEEAQCPTLHFLEGGEDSDSDSEEEDDEEEDDEDEDDDDDEEDGDEVP
Sbjct: 481 VEAGGSFGAYGAQEEAQCPTLHFLEGGEDSDSDSEEEDDEEEDDEDEDDDDDEEDGDEVP 540

Query: 541 VPSFGEAMAYFAMVKRYLTSFPIDDRVQSHILHLEHDLVHVTRKNHARQAGVRGLGHQS 599
           VPSFGEAMAYFAMVKRYLTSFPIDDRVQSHILHLEHDLVHVTRKNHARQAGVRGLGHQS
Sbjct: 541 VPSFGEAMAYFAMVKRYLTSFPIDDRVQSHILHLEHDLVHVTRKNHARQAGVRGLGHQS 599


>gi|13569924 hypothetical protein LOC81789 [Homo sapiens]
          Length = 521

 Score =  202 bits (515), Expect = 5e-52
 Identities = 128/392 (32%), Positives = 202/392 (51%), Gaps = 30/392 (7%)

Query: 4   KRRQLTFREKSRIIQEVEENPDLRKGEIARRFNIPPSTLSTILKNKRAILASERKYGVAS 63
           KRRQ +  EK +++  V+     RKG++A+ F I PSTLST LK++       R+  V  
Sbjct: 8   KRRQFSLEEKMKVVGAVDSGK--RKGDVAKEFGITPSTLSTFLKDRTKFEEKVREASVGP 65

Query: 64  TCRKTNKLSPYDKLEGLLIAWFQQIRAAGLPVKGIILKEKALRIAEELGMDDFTASNGWL 123
             RK  + + YD ++  + AWFQ+I A  + V G ++++KAL +A  LG D+F AS GWL
Sbjct: 66  Q-RKRMRSALYDDIDKAVFAWFQEIHAKNILVTGSVIRKKALNLANMLGYDNFQASVGWL 124

Query: 124 DRFRRRHGVVSCSGVARARARNAAPRTPAAPASPAAVPSEGSG-GSTTGWRAREEQPPSV 182
           +RFR RHG+       +A  R  + R              G G      W A E     +
Sbjct: 125 NRFRDRHGIA-----LKAVCREDSDRL-----------MNGLGIDKINEWHAGEII--KL 166

Query: 183 AEGYASQDVFSATETSLWYDFLPDQAAGLCGGDGRP-RQATQRLSVLLCANADGSEKLPP 241
              Y+  D+F+A ET +++  LP       G   R  ++A QRL+ L C NA G+EK+ P
Sbjct: 167 IADYSPDDIFNADETGVFFQLLPQHTLAAKGDHCRGGKKAKQRLTALFCCNASGTEKMRP 226

Query: 242 LVAGKSAKPRA--GQAGLPCDYTANSKGGVTTQALAKYLKALDTRMAAESRRVLLLAGRL 299
           L+ G+SA P        LPCDY AN    +T     ++L  +D RM    RR+LLL    
Sbjct: 227 LIVGRSASPHCLKNIHSLPCDYRANQWAWMTRDLFNEWLMQVDARMKRAERRILLLIDNC 286

Query: 300 AAQSLDTSGLRHVQLAFFP---PGTVHPLERGVVQQVKGHYRQAMLLKAMAALEGQDPSG 356
           +A ++    L  +Q+ + P      + PL  G++  +K  Y+  +L + +  L   +   
Sbjct: 287 SAHNM-LPHLERIQVGYLPSNCTAVLQPLNLGIIHTMKVLYQSHLLKQILLKLNSSEDQE 345

Query: 357 LQLGLTEALHFVAAAWQAVEPSDIAACFREAG 388
            ++ + +A+  +AAAW +V+PS +  C+++AG
Sbjct: 346 -EVDIKQAIDMIAAAWWSVKPSTVVKCWQKAG 376


>gi|22219477 tigger transposable element derived 4 [Homo sapiens]
          Length = 512

 Score =  184 bits (467), Expect = 2e-46
 Identities = 154/579 (26%), Positives = 248/579 (42%), Gaps = 97/579 (16%)

Query: 4   KRRQLTFREKSRIIQEVEENPDLRKGEIARRFNIPPSTLSTILKNKRAILASERKYGVAS 63
           K++ L+  EK  II  VE     +K EIA  + I  ++LS+I+KNK  +L +        
Sbjct: 17  KKKSLSIEEKIDIINAVESGK--KKAEIAAEYGIKKNSLSSIMKNKDKVLEAFESLRFDP 74

Query: 64  TCRKTNKLSPYDKLEGLLIAWFQQIRAAGLPVKGIILKEKALRIAEELGMDDFTASNGWL 123
             RK  + + Y  LE  L+ W++  +   +PV G +L+ KA   A++LG +DF  SNGWL
Sbjct: 75  K-RKRLRTAFYTDLEEALMRWYRIAQCLNVPVNGPMLRLKANDFAQKLGHNDFKCSNGWL 133

Query: 124 DRFRRRHGVVSCSGVARARARNAAPRTPAAPASPAAVPSEGSGGSTTGWRAREEQPPSVA 183
           DRF+ R+G+V                  A P     VP + S    T W   +   P   
Sbjct: 134 DRFKSRYGLVF----------------RAQPVEATGVPVDPS----TVWY--QNVLPYYL 171

Query: 184 EGYASQDVFSATETSLWYDFLPDQAAGLCGGD-GRPRQATQRLSVLLCANADGSEKLPPL 242
             Y  ++VF+  ET L Y  LP       G      +    R+++++  N DGSEKLP L
Sbjct: 172 NDYHPKNVFNIKETGLLYRMLPTNTFAFKGETCSVGKLCKDRITLVVGTNMDGSEKLPLL 231

Query: 243 VAGKSAKPRA--GQAGLPCDYTANSKGGVTTQALAKYLKALDTRMAAESRRVLLLAGRLA 300
           V GK   P    G   LP  Y AN    +T+    ++++ LD    A+ RRV++      
Sbjct: 232 VIGKKRTPHCFKGLKSLPVCYEANRMAWMTSDVFEQWMRKLDEEFQAQQRRVVIFVESFP 291

Query: 301 AQSLDTSGLRHVQLAFFPP---GTVHPLERGVVQQVKGHYRQAMLLKAMAALEGQDPSGL 357
           A   +   L+ ++LAFFP         +++GV++ +K  YR  ++ K ++++EG      
Sbjct: 292 AHP-EVKNLKSIELAFFPSCLSSKCIAMKQGVIKSLKIKYRHCLIKKFLSSVEGSKE--F 348

Query: 358 QLGLTEALHFVAAAWQAVEPSDIAACFREAGFGGGPNATITTSLKSEGEEEEEEEEEEEE 417
              L +A+  +   W+AV P  I   + EAGF                      + ++ E
Sbjct: 349 TFSLLDAVDTLHLCWRAVTPETIVKSYEEAGF----------------------KSQKGE 386

Query: 418 EEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEEEEDEESSSEGLEAEDWA 477
            +    E++   +   +  G G E  E   +EE   +D D E  E   +           
Sbjct: 387 SDITNAEKDTGLDLVADALGAGVEFPEGLSIEEYAALDDDLETCEAAPNG---------- 436

Query: 478 QGVVEAGGSFGAYGAQEEAQCPTLHFLEGGEDSDSDSEEEDDEEEDDEDEDDDDDEEDGD 537
                                          DS    E + DE      +++DDD   G 
Sbjct: 437 -------------------------------DSICTKESKSDETGFYTSDEEDDDGSPGT 465

Query: 538 EVPVPSFGEAMAYFAMVKRYLTSFPIDDRVQSHILHLEH 576
           E+P+PS  EA+     +K++L S  ++D +Q+ +  LE+
Sbjct: 466 ELPLPSKSEAITALDTLKKFLRSQDMNDGLQNSLADLEN 504


>gi|23312394 tigger transposable element derived 3 [Homo sapiens]
          Length = 471

 Score =  145 bits (365), Expect = 1e-34
 Identities = 136/455 (29%), Positives = 202/455 (44%), Gaps = 58/455 (12%)

Query: 4   KRRQLTFREKSRIIQEVEENPDLRKGEIARRFNIPPSTLSTILKNKRAILASERKYGVAS 63
           K   L+  EK ++++ ++E+  + + E+ARRF +    +S I KNK  +LA     G A+
Sbjct: 8   KLHALSLAEKIQVLELLDESK-MSQSEVARRFQVSQPQISRICKNKEKLLADWCS-GTAN 65

Query: 64  TCRKTNKLSPYDKLEGLLIAWFQQIRAAGLPVKGIILKEKALRIAEELGMDDFTASNGWL 123
             RK  + S Y  ++  L+ W+   RA    V G +L  KA  +A+ +G  DF  S GWL
Sbjct: 66  RERKRKRESKYSGIDEALLCWYHIARAKAWDVTGPMLLHKAKELADIMG-QDFVPSIGWL 124

Query: 124 DRFRRRHGVVSCSGVARARARNAAPRTPAAPASPAAVPSEGSGGSTTGWRAREEQPPSVA 183
            R++RR+ V                R   AP+ P   P  G           + Q P   
Sbjct: 125 VRWKRRNNV------------GFGARHVLAPSFPPEPPPPG--------LTSQAQLPLSL 164

Query: 184 EGYASQDVFSATETSLWYDFLPDQAAGLCGGDGRPRQATQRLSVLLCANADGSEKLPPLV 243
           + ++ +DVF   E  L Y  +P       G  G    A  ++ VLLCAN+ G+EK   L+
Sbjct: 165 KDFSPEDVFGCAELPLLYRAVP-------GSFG----ACDQVQVLLCANSRGTEKRRVLL 213

Query: 244 AGKSAKPRA----GQAGLPCDYTANSKGGVTTQALAKYLKALDTRMAAESRRV-LLLAGR 298
            G  A PR         LP  Y  +   G+      ++L   D  M  + R+V LLLA R
Sbjct: 214 GGLQAAPRCFFGIRSEALPASYHPDL--GI---PWLEWLAQFDRDMGQQGRQVALLLAAR 268

Query: 299 LAAQSLDTSGLRHVQ-LAFFPPGTVHPLERGVVQQVKGHYRQAMLLKAMAALEGQD---- 353
           +  +     GL HV+ L      T  PL   VV+  K HYR  +L K  A    +D    
Sbjct: 269 VVEELAGLPGLYHVKLLPLAASSTTPPLPSSVVRAFKAHYRHRLLGKLAAIQSERDGTSL 328

Query: 354 -PSGLQLGLTEALHFVAAAWQAVEPSDIAACFREAGFGGG---PNATITTSLKS-----E 404
             +G  + + +ALH  +AAW  V P  I + F + G   G   P++  T+ +        
Sbjct: 329 AEAGAGITVLDALHVASAAWAKVPPQLIFSSFIQEGLAPGKTPPSSHKTSEMPPVPGGLS 388

Query: 405 GEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEG 439
            EE     + E EE   G  +EE G E+E+   EG
Sbjct: 389 LEEFSRFVDLEGEEPRSGVCKEEIGTEDEKGDREG 423


>gi|23312392 tigger transposable element derived 2 [Homo sapiens]
          Length = 525

 Score =  136 bits (343), Expect = 5e-32
 Identities = 142/534 (26%), Positives = 237/534 (44%), Gaps = 101/534 (18%)

Query: 4   KRRQLTFREKSRIIQEVEENPDLRKGEIARRFNIPPSTLSTILKNKRAIL----ASERKY 59
           KR  LT ++K  II+++EE    +K  +   + I  ST+  I KNK  I+    +S+   
Sbjct: 6   KRVVLTIKDKLDIIKKLEEGISFKKLSVV--YGIGESTVRDIKKNKERIINYANSSDPTS 63

Query: 60  GVASTCRKTNKLSPYDKLEGLLIAWFQQIRAAGLPVKGIILKEKALRIAEELGMD-DFTA 118
           GV+   RK+ K S Y++L+ ++I WF Q +  G+PV G I  ++A    + LGM+ DF A
Sbjct: 64  GVSK--RKSMKSSTYEELDRVMIEWFNQQKTDGIPVSGTICAKQAKFFFDALGMEGDFNA 121

Query: 119 SNGWLDRFRRRHGVVSCSGV-ARARARNAAPRTPAAPASPAAVPSEGSGGSTTGWRAREE 177
           S+GWL RF++RHG+   +G   + +    A R                 GS   +  +E 
Sbjct: 122 SSGWLTRFKQRHGIPKAAGKGTKLKGDETAAREFC--------------GSFQEFVEKEN 167

Query: 178 QPPSVAEGYASQDVFSATETSLWYDFLP--------DQAAGLCGGDGRPRQATQRLSVLL 229
             P        + ++ A +T L++  LP        DQ+   C      R + +R+ ++ 
Sbjct: 168 LQP--------EQIYGADQTGLFWKCLPSRTLTLETDQSTSGC------RSSRERIIIMC 213

Query: 230 CANADGSEKLPPLVAGKSAKPRAGQ----AGLPCDYTANS----KGGVTTQALAKYL--- 278
           CANA G  KL   V GK+ KPRA +    + LP  Y +      +  V  Q   KY    
Sbjct: 214 CANATGLHKLNLCVVGKAKKPRAFKGTDLSNLPVTYYSQKGAWIEQSVFRQWFEKYFVPQ 273

Query: 279 --KALDTRMAAESRRVLLLAGRLAA--QSLDTSGLRHVQLAFFPPGT---VHPLERGVVQ 331
             K L ++   E + VLLL    A   + + +S    + + + PP     + P+ +GV+ 
Sbjct: 274 VQKHLKSKGLLE-KAVLLLDFPPARPNEEMLSSDDGRIIVKYLPPNVTSLIQPMSQGVLA 332

Query: 332 QVKGHYRQAMLLKAMAALEGQDPSGLQLGLT--EALHFVAAAWQAVEPSDIAACFREAGF 389
            VK +YR  +L K M   EG DP      LT  +A++ V+ AW  V+ S I   +++   
Sbjct: 333 TVKRYYRAGLLQKYMD--EGNDPKIFWKNLTVLDAIYEVSRAWNMVKSSTITKAWKKLFP 390

Query: 390 GGGPN------------ATITTSLKSEGEEEEEEEEEEEE---------------EEGEG 422
           G   N            A + T L++  E E  + E  ++               +    
Sbjct: 391 GNEENSGMNIDEGAILAANLATVLQNTEECEHVDIENIDQWFDSRSSDSSCQVLTDSESA 450

Query: 423 EEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEE-----EEEDEESSSEGL 471
           E++ +  E++        EL  E+ +  +  ++  E      E++D+   S+ L
Sbjct: 451 EDQTKAAEQKPSSKSRKTELNPEKHISHKAALEWTENLLDYLEQQDDMLLSDKL 504


>gi|22547224 jerky homolog-like [Homo sapiens]
          Length = 524

 Score =  117 bits (293), Expect = 3e-26
 Identities = 127/491 (25%), Positives = 211/491 (42%), Gaps = 59/491 (12%)

Query: 4   KRRQLTFREKSRIIQEVEENPDLRKGEIARRFNIPPSTLSTILKNKRAIL--ASERKYGV 61
           KR  LT ++K  II+++E+    +  ++A  + I  +T+  I KNK  I+  AS      
Sbjct: 6   KRVVLTIKDKLDIIKKLEDGGSSK--QLAVIYGIGETTVRDIRKNKEKIITYASSSDSTS 63

Query: 62  ASTCRKTNKLSPYDKLEGLLIAWFQQIRAAGLPVKGIILKEKALRIAEELGMD-DFTASN 120
               RK+ K S Y++L+  ++ WF Q RA G P+ G I  ++A      LGMD DF  S 
Sbjct: 64  LLAKRKSMKPSMYEELDRAMLEWFNQQRAKGNPISGPICAKRAEFFFYALGMDGDFNPSA 123

Query: 121 GWLDRFRRRHGVVSCSGVARARARNAAPRTPAAPASPAAVPSEGSGGSTTGWRAREEQPP 180
           GWL RF++RH +           R    R         AV  E    +   +  RE   P
Sbjct: 124 GWLTRFKQRHSI-----------REINIRNERLNGDETAV--EDFCNNFRDFIERENLQP 170

Query: 181 SVAEGYASQDVFSATETSLWYDFLPDQAA---GLCGGDGRPRQATQRLSVLLCANADGSE 237
                   + +++A ET L++  LP + +   G C   G  +   +R++++ CANA G  
Sbjct: 171 --------EQIYNADETGLFWKCLPSRISVIKGKCTVPGH-KSIEERVTIMCCANATGLH 221

Query: 238 KLPPLVAGKSAKPRAGQA----GLPCDYTANSKGGVTTQALAKYLKALDTRMAAE----- 288
           KL   V GK+ KPR+ ++     LP  Y +     +      ++   +      E     
Sbjct: 222 KLKLCVVGKAKKPRSFKSTDTLNLPVSYFSQKGAWMDLSIFRQWFDKIFVPQVREYLRSK 281

Query: 289 ---SRRVLLL--AGRLAAQSLDTSGLRHVQLAFFPPGT---VHPLERGVVQQVKGHYRQA 340
               + VLLL  +     +++  S    +   + PP     + P ++GV+  +K +YR  
Sbjct: 282 GLQEKAVLLLDNSPTHPNENVLRSDDGQIFAKYLPPNVASLIQPSDQGVIATMKRNYRAG 341

Query: 341 MLLKAMAALEGQDPSGL--QLGLTEALHFVAAAWQAVEPSDIAACFREAGFGGGPNATIT 398
           +L   +   EG D      +L L +AL+ +A AW  V+P  I+  +++      P     
Sbjct: 342 LLQNNLE--EGNDLKSFWKKLTLLDALYEIAMAWNLVKPVTISRAWKKI----LPMVEEK 395

Query: 399 TSLKSEGEEEEEEEEEEEEEEGEGEE----EEEEGEEEEEEGGEGEELGEEEEVEEEGDV 454
            SL  + E+          +  +G E    E  E   E +    G E+  + E+      
Sbjct: 396 ESLDFDVEDISVATVAAILQHTKGLENVTTENLEKWLEVDSTEPGYEVLTDSEIIRRAQG 455

Query: 455 DSDEEEEEDEE 465
            +DE  E +EE
Sbjct: 456 QADESSENEEE 466


>gi|144922631 tigger transposable element derived 5 [Homo sapiens]
          Length = 593

 Score =  114 bits (285), Expect = 3e-25
 Identities = 112/433 (25%), Positives = 189/433 (43%), Gaps = 61/433 (14%)

Query: 5   RRQLTFREKSRIIQEVEENPDLRKGEIARRFNIPPSTLSTILKNKRAIL-ASERKYGVAS 63
           R+  + ++K + I+ V+     R+  + R F +P  TL   LK++  +    E+  G   
Sbjct: 4   RKAYSIKDKLQAIERVKGGE--RQASVCRDFGVPGGTLRGWLKDEPKLRWFLEQLGGEVG 61

Query: 64  TCRKTNKLSPYDKLEGLLIAWFQQIRAAGLPVKGIILKEKALRIAEELGMDD--FTASNG 121
           T RK  +L+  ++++  + AWF  +R  G+P+ G +++ +A   A ++   +  F AS+G
Sbjct: 62  TQRKKMRLANEEEIDRAVYAWFLALRQHGVPLSGPLIQAQAEAFARQIYGPECTFKASHG 121

Query: 122 WLDRFRRRHGVVSCSGVARARARNAAPRTPAAPASPAAV-PSEGSGGSTTGWRAREEQPP 180
           W  R+++RHG+ S     R       P    AP  P    P+  SG      RA    PP
Sbjct: 122 WFWRWQKRHGISS----QRFYGEAGPPAPSPAPGPPVKEEPALPSGAGPLPDRAPAPPPP 177

Query: 181 SVAEGYASQDVFSATETSLWYDFLPDQAAGL------CGGDGRPRQATQRLSVLLCANAD 234
           +   GY  + ++SA+ T L++  LP+QAA         GG GR R    R++VLL AN  
Sbjct: 178 AEG-GYGDEQIYSASVTGLYWKLLPEQAAPPGAGDPGAGGCGR-RWRGDRVTVLLAANLT 235

Query: 235 GSEKLPPLVAGKSAKPRA----GQAGLPCDYTANSKGGVTTQALAKY--------LKALD 282
           GS KL PLV G+   P +     Q   P  Y  +    ++   L  +        +K   
Sbjct: 236 GSHKLKPLVIGRLPDPPSLRHHNQDKFPASYRYSPDAWLSRPLLRGWFFEEFVPGVKRYL 295

Query: 283 TRMAAESRRVLLL--------AGRLAAQSLDTSGLR-----------------HVQLAFF 317
            R   + + VLL+        A  + A   + + +R                  V++ F 
Sbjct: 296 RRSCLQQKAVLLVAHPPCPSPAASMPALDSEDAPVRCRPEPLGPPEELQTPDGAVRVLFL 355

Query: 318 PPGTVH-----PLERGVVQQVKGHYRQAMLLKAMAALEGQDPSGLQ-LGLTEALHFVAAA 371
             G+       PLE+GVV   K  Y++ +L  A++   G     ++   L + L+    +
Sbjct: 356 SKGSSRAHIPAPLEQGVVAAFKQLYKRELLRLAVSCASGSPLDFMRSFMLKDMLYLAGLS 415

Query: 372 WQAVEPSDIAACF 384
           W  V+   I  C+
Sbjct: 416 WDLVQAGSIERCW 428


>gi|22325392 tigger transposable element derived 7 [Homo sapiens]
          Length = 549

 Score =  112 bits (279), Expect = 1e-24
 Identities = 131/528 (24%), Positives = 215/528 (40%), Gaps = 80/528 (15%)

Query: 4   KRRQLTFREKSRIIQEVEENPDLRKGEIARRFNIPPSTLSTILKNKRAILASERKYG--- 60
           K   L   EK +++  +E    L+   +   F I  ST   I KNK+ IL    K     
Sbjct: 6   KYTTLNLEEKMKVLSRIEAGRSLKS--VMDEFGISKSTFYDIKKNKKLILDFVLKQDMPL 63

Query: 61  VASTCRKTNKLSPYDKLEGLLIAWFQQIRAAGLPVKGIILKEKALRIAEELGMDDFTASN 120
           V +  RK    + Y  ++  +  W+QQ R+AG+PV+G+ L+  A R A   G  DF AS 
Sbjct: 64  VGAEKRKRTTGAKYGDVDDAVYMWYQQKRSAGVPVRGVELQAAAERFARCFGRTDFKAST 123

Query: 121 GWLDRFRRRHGVVSCSGVARARARNAAPRTPAAPASPAAVPSEGSGGSTTGWRAREEQPP 180
           GWL RFR RH + +  G       + +          + +  E                 
Sbjct: 124 GWLFRFRNRHAIGNRKGCGEQVLSSVSENVEPFRQKLSMIIKE----------------- 166

Query: 181 SVAEGYASQDVFSATETSLWYDFLPDQAAGLCGGDGRPRQA--TQRLSVLLCANADGSEK 238
              E      ++S  ET L++  +P+ +         P +    +RLS  LCANADG+ K
Sbjct: 167 ---EKLCLAQLYSGDETDLFWKSMPENSQASRKDICLPGKKINKERLSAFLCANADGTHK 223

Query: 239 LPPLVAGKSAKPRA---GQAGLPCDYTANSKGGVTTQALA-----------KYLKALDTR 284
           L  ++ GKS  P++     + LP  Y  +     T +  +           ++ +    R
Sbjct: 224 LKSIIIGKSKLPKSVKEDTSTLPVIYKPSKDVWFTRELFSEWFFQNFVPEVRHFQLNVLR 283

Query: 285 MAAESRRVLLLAGRLAA----QSLDTSGLRHVQLAFFPPGT---VHPLERGVVQQVKGHY 337
              E  R LLL     A    +SL TS    ++  FFP  T   + P+ +GV+   K  Y
Sbjct: 284 FHDEDVRALLLLDSCPAHPSSESL-TSEDGRIKCMFFPHNTSTLIQPMNQGVILSCKRLY 342

Query: 338 RQAMLLKAMAALEGQDP---------SGLQL-GLTEALHFVAAAWQAVEPSDIAACFR-- 385
           R   L +++   E  D          S +++  +  A+   A +W+ V+   IA  +   
Sbjct: 343 RWKQLEESLVIFEESDDEQEKGDKGVSKIKIYNIKSAIFNWAKSWEEVKQITIANAWENL 402

Query: 386 ------EAGFGGGPNATITTSLKSEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEG 439
                 E  F G  +      L+  GE E + +++     G    +EE+G   + +GG  
Sbjct: 403 LYKKEPEYDFQGLEHGDYREILEKCGELETKLDDDRVWLNG----DEEKGCLLKTKGGIT 458

Query: 440 EELGEEEEVEEEGDVDSDEEEEEDEESSSEGLEAEDWAQGVVEAGGSF 487
           +E+     V++ G+     E++  E   S   E+ D+    V+A   F
Sbjct: 459 KEV-----VQKGGEA----EKQTAEFKLSAVRESLDYLLDFVDATPEF 497


>gi|117938293 jerky isoform a [Homo sapiens]
          Length = 568

 Score =  108 bits (270), Expect = 1e-23
 Identities = 122/432 (28%), Positives = 183/432 (42%), Gaps = 63/432 (14%)

Query: 4   KRRQLTFREKSRIIQEVEENPDLRKGEIARRFNIPPSTLSTILKNKRAILA--SERKYGV 61
           KR  LT +EK  I   +E+  + RK  + + +N+  STL  I  +K  +L   +      
Sbjct: 16  KRVVLTLKEKIDICTRLEKG-ESRKA-LMQEYNVGMSTLYDIRAHKAQLLRFFASSDSNK 73

Query: 62  ASTCRKTNKLSPYDKLEGLLIAWFQQIRAAGLPVKGIILKEKALRIAEELGMDD-FTASN 120
           A   R+T      + L+ +L  WF   R+ G+PV G +L EKA    E++ + +    S 
Sbjct: 74  ALEQRRTLHTPKLEHLDRVLYEWFLGKRSEGVPVSGPMLIEKAKDFYEQMQLTEPCVFSG 133

Query: 121 GWLDRFRRRHGV--VSCSGVARARARNAAPRTPAAPASPAAVPSEGSGGSTTGWRAREEQ 178
           GWL RF+ RHG+  +  S   ++    AA +  A   S AA                   
Sbjct: 134 GWLWRFKARHGIKKLDASSEKQSADHQAAEQFCAFFRSLAA------------------- 174

Query: 179 PPSVAEGYASQDVFSATETSLWYDFLPDQAAGLCGGDGRPRQATQRLSVLLCANADGSEK 238
                 G +++ V++A ET L++  LP+      G    P+Q   RL+VL+CANA GS +
Sbjct: 175 ----EHGLSAEQVYNADETGLFWRCLPNPTPE-GGAVPGPKQGKDRLTVLMCANATGSHR 229

Query: 239 LPPLVAGKSAKPRA--GQAGLPCDYTANSKGGVTTQALAKYLKALDTRMAAESRRVLLLA 296
           L PL  GK + PRA  G   LP  Y A     V  +  + +   +      E  R + L 
Sbjct: 230 LKPLAIGKCSGPRAFKGIQHLPVAYKAQGNAWVDKEIFSDWFHHIFVPSVREHFRTIGLP 289

Query: 297 GRLAAQSLDTSGLRHVQLA----------FFPPGT---VHPLERGVVQQVKGHYRQAMLL 343
               A  L  S   H Q A          F P      V P+E+G+ +    ++     +
Sbjct: 290 EDSKAVLLLDSSRAHPQEAELVSSNVFTIFLPASVASLVQPMEQGIRRDFMRNF-----I 344

Query: 344 KAMAALEGQDPSGLQLGLTEALHFVAAAWQAVEPSDIAACFREAGFGGGPNATITTSLKS 403
                L+G      +  + +A+  VA AW AV PS +   FR A     P+        +
Sbjct: 345 NPPVPLQGPH---ARYNMNDAIFSVACAWNAV-PSHV---FRRAWRKLWPSVAF-----A 392

Query: 404 EGEEEEEEEEEE 415
           EG   EEE E E
Sbjct: 393 EGSSSEEELEAE 404


>gi|117938295 jerky isoform b [Homo sapiens]
          Length = 556

 Score =  108 bits (270), Expect = 1e-23
 Identities = 122/432 (28%), Positives = 183/432 (42%), Gaps = 63/432 (14%)

Query: 4   KRRQLTFREKSRIIQEVEENPDLRKGEIARRFNIPPSTLSTILKNKRAILA--SERKYGV 61
           KR  LT +EK  I   +E+  + RK  + + +N+  STL  I  +K  +L   +      
Sbjct: 16  KRVVLTLKEKIDICTRLEKG-ESRKA-LMQEYNVGMSTLYDIRAHKAQLLRFFASSDSNK 73

Query: 62  ASTCRKTNKLSPYDKLEGLLIAWFQQIRAAGLPVKGIILKEKALRIAEELGMDD-FTASN 120
           A   R+T      + L+ +L  WF   R+ G+PV G +L EKA    E++ + +    S 
Sbjct: 74  ALEQRRTLHTPKLEHLDRVLYEWFLGKRSEGVPVSGPMLIEKAKDFYEQMQLTEPCVFSG 133

Query: 121 GWLDRFRRRHGV--VSCSGVARARARNAAPRTPAAPASPAAVPSEGSGGSTTGWRAREEQ 178
           GWL RF+ RHG+  +  S   ++    AA +  A   S AA                   
Sbjct: 134 GWLWRFKARHGIKKLDASSEKQSADHQAAEQFCAFFRSLAA------------------- 174

Query: 179 PPSVAEGYASQDVFSATETSLWYDFLPDQAAGLCGGDGRPRQATQRLSVLLCANADGSEK 238
                 G +++ V++A ET L++  LP+      G    P+Q   RL+VL+CANA GS +
Sbjct: 175 ----EHGLSAEQVYNADETGLFWRCLPNPTPE-GGAVPGPKQGKDRLTVLMCANATGSHR 229

Query: 239 LPPLVAGKSAKPRA--GQAGLPCDYTANSKGGVTTQALAKYLKALDTRMAAESRRVLLLA 296
           L PL  GK + PRA  G   LP  Y A     V  +  + +   +      E  R + L 
Sbjct: 230 LKPLAIGKCSGPRAFKGIQHLPVAYKAQGNAWVDKEIFSDWFHHIFVPSVREHFRTIGLP 289

Query: 297 GRLAAQSLDTSGLRHVQLA----------FFPPGT---VHPLERGVVQQVKGHYRQAMLL 343
               A  L  S   H Q A          F P      V P+E+G+ +    ++     +
Sbjct: 290 EDSKAVLLLDSSRAHPQEAELVSSNVFTIFLPASVASLVQPMEQGIRRDFMRNF-----I 344

Query: 344 KAMAALEGQDPSGLQLGLTEALHFVAAAWQAVEPSDIAACFREAGFGGGPNATITTSLKS 403
                L+G      +  + +A+  VA AW AV PS +   FR A     P+        +
Sbjct: 345 NPPVPLQGPH---ARYNMNDAIFSVACAWNAV-PSHV---FRRAWRKLWPSVAF-----A 392

Query: 404 EGEEEEEEEEEE 415
           EG   EEE E E
Sbjct: 393 EGSSSEEELEAE 404


>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
            sapiens]
          Length = 1152

 Score =  103 bits (257), Expect = 5e-22
 Identities = 65/137 (47%), Positives = 84/137 (61%), Gaps = 6/137 (4%)

Query: 402  KSEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEEE 461
            + EGE EEEE E E EEEGEGE EEEEGE E EE GEGE  GEEEE E +G+ + +E E 
Sbjct: 873  EGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGE--GEEEEGEGKGEEEGEEGEG 930

Query: 462  EDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHFLEG-GEDSDSDSEEEDDE 520
            E EE   EG E ED      E  G +   G +EE +       EG GE+ + + EEE+ E
Sbjct: 931  EGEEEEGEG-EGEDGEGEGEEEEGEW--EGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGE 987

Query: 521  EEDDEDEDDDDDEEDGD 537
             E +E+E +++ EE+G+
Sbjct: 988  GEGEEEEGEEEGEEEGE 1004



 Score = 97.8 bits (242), Expect = 2e-20
 Identities = 67/155 (43%), Positives = 85/155 (54%), Gaps = 22/155 (14%)

Query: 407 EEEEEEEEEEEEEGEGEEEEEEGEEEEEEG------GEGEELGEEEEVEEEGDVDSDEEE 460
           EE + E EEEEEEGEGEEEE EGEEEE EG      G+GEE GEE E EEEG+    E E
Sbjct: 820 EEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGE 879

Query: 461 EE------DEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHFLEGGEDSDSDS 514
           EE      +EE   EG E E   +G  E  G     G +EE +       E GE+ + + 
Sbjct: 880 EEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGE----GEEEEGEGKG---EEEGEEGEGEG 932

Query: 515 EEEDDEEEDDEDEDDDDDEE---DGDEVPVPSFGE 546
           EEE+ E E ++ E + ++EE   +G+E      GE
Sbjct: 933 EEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGE 967



 Score = 94.4 bits (233), Expect = 3e-19
 Identities = 66/155 (42%), Positives = 83/155 (53%), Gaps = 21/155 (13%)

Query: 402  KSEGEEEEEEEEEEEEEEGEGEEE----EEEGEEEEEEG------GEGEE-----LGEEE 446
            + EGEEE E E EEEE EG+GEEE    E EGEEEE EG      GEGEE      GEEE
Sbjct: 901  EGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEE 960

Query: 447  EVEEEGDVDSD------EEEEEDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPT 500
            E E EG+ + +      E E E+EE   EG E E   +G  E  G     G  EE +   
Sbjct: 961  EGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGE 1020

Query: 501  LHFLEGGEDSDSDSEEEDDEEEDDEDEDDDDDEED 535
            +     GE+ + + EEE+ EEE +E E + + EE+
Sbjct: 1021 VEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEEN 1055



 Score = 93.6 bits (231), Expect = 5e-19
 Identities = 62/170 (36%), Positives = 88/170 (51%), Gaps = 42/170 (24%)

Query: 402 KSEGEEEEEEEEEE--------------EEEEGEGEEEEEEGEEEEEEGGEGEELGEEEE 447
           K +GEE+E++E E+              EEE GEGEEEE + EEEEE+ GEG+E GE EE
Sbjct: 704 KRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEE 763

Query: 448 V-------------------EEEGDVDSDEEEEEDEESSSEGLEAEDWAQGVVEAGGSFG 488
           V                   EE+G+ + D+ E E+EE+   G E E+   G VE G    
Sbjct: 764 VEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEE--GGEVEGGEVEE 821

Query: 489 AYGAQEEAQCPTLHFLEGGEDSDSDSEEEDDEEEDDEDEDDDDDEEDGDE 538
             G +EE +       E GE  + + E E++E E +E+E +   EE+G+E
Sbjct: 822 GKGEREEEE-------EEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEE 864



 Score = 93.2 bits (230), Expect = 6e-19
 Identities = 62/138 (44%), Positives = 81/138 (58%), Gaps = 13/138 (9%)

Query: 402  KSEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEE-EVEEEGDVDSDEEE 460
            + EGE E EEE E E EEGEGE EEEEGE E EE  EGEE GEEE E EEEG+ + +EEE
Sbjct: 959  EEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEE-EEGEEEGEEEGEGEEEGEGEGEEEE 1017

Query: 461  EEDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHFLEGGEDSDSDSEEEDDE 520
            E + E   EG E E   +G  E G   G    +E          EG E+  +  EEE++E
Sbjct: 1018 EGEVEGEVEGEEGE--GEGEEEEGEEEGEEREKEG---------EGEENRRNREEEEEEE 1066

Query: 521  EEDDEDEDDDDDEEDGDE 538
             +  E  +++++ +DG+E
Sbjct: 1067 GKYQETGEEENERQDGEE 1084



 Score = 90.9 bits (224), Expect = 3e-18
 Identities = 60/149 (40%), Positives = 83/149 (55%), Gaps = 19/149 (12%)

Query: 402 KSEGEEEEEEEEEEEEEEGEGEEEEEEGE-EEEEEGGE------GEELGEEEEVEEEG-- 452
           K E    +EE+ EEE ++GEGEEEE EG  EE+EEGGE       E  GE EE EEEG  
Sbjct: 776 KKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEG 835

Query: 453 ---DVDSDEEEEEDEESSSEGLEAEDWAQGVVEAGGSFG-AYGAQEEAQCPTLHFLEGGE 508
              + + +EEE E EE   EG   E+  +G  E  G  G   G +EE +       EG E
Sbjct: 836 EEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEG------EGEE 889

Query: 509 DSDSDSEEEDDEEEDDEDEDDDDDEEDGD 537
           + + + EEE+ E E +E+ + + +EE+G+
Sbjct: 890 EGEGEGEEEEGEGEGEEEGEGEGEEEEGE 918



 Score = 90.5 bits (223), Expect = 4e-18
 Identities = 66/157 (42%), Positives = 86/157 (54%), Gaps = 32/157 (20%)

Query: 402 KSEGEEEEEEEEEEEEEEG-------------EGEEEEEEGEEEEEEGGEGEE---LGEE 445
           + EGEEEE E   EE+EEG             E EEEEEEGE EEEE GEGEE    GEE
Sbjct: 793 QGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEE-GEGEEEEGEGEE 851

Query: 446 EEVEEEGDVDSD--EEEEEDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHF 503
           EE E +G+ + +  E EEE EE   EG E E   +G  E  G     G +EE +      
Sbjct: 852 EEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGE----GEEEEGEG----- 902

Query: 504 LEGGEDSDSDSEEEDDE---EEDDEDEDDDDDEEDGD 537
            EG E+ + + EEE+ E   EE+ E+ + + +EE+G+
Sbjct: 903 -EGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGE 938



 Score = 89.7 bits (221), Expect = 7e-18
 Identities = 67/172 (38%), Positives = 89/172 (51%), Gaps = 26/172 (15%)

Query: 402  KSEGEEEEEEEEEE------EEEEGEGEEEEEEGEEEEEEGGEG----------EELGEE 445
            + EGEEEE E E E      EEEEGE E EEEEGE E EE GEG          EE GE 
Sbjct: 929  EGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEG 988

Query: 446  EEVEEEGDVDSDEEEEEDEESSSEGLEAEDW-AQGVVEAGGSFGAYGAQEEAQCPTLHFL 504
            E  EEEG+ + +EE E +EE   EG E E+   +G VE     G  G +EE +       
Sbjct: 989  EGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGE-GEEEEGE------- 1040

Query: 505  EGGEDSDSDSE-EEDDEEEDDEDEDDDDDEEDGDEVPVPSFGEAMAYFAMVK 555
            E GE+ + + E EE+    ++E+E++   +E G+E      GE     + +K
Sbjct: 1041 EEGEEREKEGEGEENRRNREEEEEEEGKYQETGEEENERQDGEEYKKVSKIK 1092



 Score = 72.8 bits (177), Expect = 9e-13
 Identities = 56/161 (34%), Positives = 82/161 (50%), Gaps = 30/161 (18%)

Query: 404 EGEEEEEEEEEEEEEEGEGEEEEE-------EGEEEEEEGGEGEELGEEEEVEEEGDVDS 456
           EGE+E  E+EE ++ +GE +E++E       E  +E EEGGE EE GE EE  EEGD + 
Sbjct: 691 EGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGE-EEHGEGEE--EEGDREE 747

Query: 457 DEEEE------------EDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTL--- 501
           +EE+E            E E    EG   ++   G  E G   G  G  EE +       
Sbjct: 748 EEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEE 807

Query: 502 ----HFLEGGEDSDSDSEEEDDEEE-DDEDEDDDDDEEDGD 537
                 +EGGE  +   E E++EEE + E+E+ + +EE+G+
Sbjct: 808 KEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGE 848



 Score = 57.8 bits (138), Expect = 3e-08
 Identities = 41/145 (28%), Positives = 69/145 (47%), Gaps = 9/145 (6%)

Query: 404 EGEEEEEEEEE----EEEEEGEGEEEEEEGEEEEEEGGEGEEL-----GEEEEVEEEGDV 454
           + EE E+ E++    E E  GEGE+E  E EE ++  GE +E      G ++E  +E + 
Sbjct: 670 QDEEREKGEKDKGRGEMERPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEE 729

Query: 455 DSDEEEEEDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHFLEGGEDSDSDS 514
             +EE  E EE   +  E E+      E G      G +E+ +         G++   + 
Sbjct: 730 GGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEE 789

Query: 515 EEEDDEEEDDEDEDDDDDEEDGDEV 539
           E +  E E++E E   +++E+G EV
Sbjct: 790 EGDQGEGEEEETEGRGEEKEEGGEV 814



 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 29/70 (41%), Positives = 43/70 (61%), Gaps = 1/70 (1%)

Query: 401  LKSEGEEEEEEEE-EEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEE 459
            ++ E E EE E E EEEE E EGEE E+EGE EE      EE  EE + +E G+ +++ +
Sbjct: 1021 VEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQETGEEENERQ 1080

Query: 460  EEEDEESSSE 469
            + E+ +  S+
Sbjct: 1081 DGEEYKKVSK 1090



 Score = 50.4 bits (119), Expect = 5e-06
 Identities = 42/147 (28%), Positives = 71/147 (48%), Gaps = 33/147 (22%)

Query: 402 KSEGEEEEEEEEEEEE--EEGEG-----EEEEEEGEEEEEEGGEGEELGE-EEEVEEEGD 453
           KS GE E+  E   +   EEG       ++EE E  E+++  GE E  GE E+E+ E+ +
Sbjct: 642 KSVGEAEDGPEGRGDGTCEEGSSGAEHWQDEEREKGEKDKGRGEMERPGEGEKELAEKEE 701

Query: 454 VDSDEEEEEDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHFLEGGEDSDSD 513
               + EE++++   +G + E                   +E +       EGGE+   +
Sbjct: 702 WKKRDGEEQEQKEREQGHQKE-----------------RNQEME-------EGGEEEHGE 737

Query: 514 SEEED-DEEEDDEDEDDDDDEEDGDEV 539
            EEE+ D EE++E E +  +E +G+EV
Sbjct: 738 GEEEEGDREEEEEKEGEGKEEGEGEEV 764


>gi|22209001 hypothetical protein LOC200765 [Homo sapiens]
          Length = 591

 Score = 95.1 bits (235), Expect = 2e-19
 Identities = 99/420 (23%), Positives = 174/420 (41%), Gaps = 64/420 (15%)

Query: 5   RRQLTFREKSRIIQEVEENPDLRKGEIARRFNIPPSTLSTILKNKRAILASERKYGVAST 64
           R  LT  +K  +I+  EE   + K EI RR  +   T+S ++  K   L   +     +T
Sbjct: 12  RTSLTLNQKLEMIKLSEEG--MSKAEIGRRLGLLRQTVSQVVNAKEKFLKEVKSATPMNT 69

Query: 65  CRKTNKLSPYDKLEGLLIAWFQQIRAAGLPVKGIILKEKALRI--------AEELGMDDF 116
                + S    +E +L+ W +   +  +P+   +++ KAL +          E   + F
Sbjct: 70  RMIRKRNSLIADMEKVLVVWIEDQTSRNIPLSQSLIQNKALTLFNSMKAERGVEAAEEKF 129

Query: 117 TASNGWLDRFRRR---HGVVSCSGVARARARNAAPRTPAAPASPAAVPSEGSGGSTTGWR 173
            AS GW  RF+ R   H + +    A A    AA    + P + A +  EG         
Sbjct: 130 EASRGWFMRFKERSHFHNIKAQGEAASADVEAAA----SYPEALAKIIDEG--------- 176

Query: 174 AREEQPPSVAEGYASQDVFSATETSLWYDFLPDQAAGLCGGDGRP--RQATQRLSVLLCA 231
                      GY  Q +F+  ET+ ++  +P +          P  + +  RL++LL A
Sbjct: 177 -----------GYTKQQIFNVDETAFYWKKMPSRTFIAREEKSVPGFKASKDRLTLLLGA 225

Query: 232 NADGSEKLPPLVAGKSAKPRA----GQAGLPCDYTANSKGGVT----TQALAKYLKALDT 283
           NA G  KL P++   S  PRA     ++ LP  Y  NSK  +T    T    +Y K    
Sbjct: 226 NAAGDFKLKPMLIYHSENPRALKNYTKSTLPVLYKWNSKARMTAHLFTAWFTEYFKPTVE 285

Query: 284 RMAAESR---RVLLLAGRLAAQSLDTSGL-RHVQLAFFPPGT---VHPLERGVVQQVKGH 336
              +E +   ++LLL     +       +   + + F P  T   + P+++GV+   K +
Sbjct: 286 TYCSEKKIPFKILLLIDNAPSHPRALMEIYEEINVIFMPANTTSILQPMDQGVISTFKSY 345

Query: 337 YRQAMLLKAMAALEG--QDPSGLQ--------LGLTEALHFVAAAWQAVEPSDIAACFRE 386
           Y +    KA+AA++    D SG            + +A+  +  +W+ V+ S +   +++
Sbjct: 346 YLRNTFHKALAAMDSDVSDGSGQSKLKTFWKGFTILDAIKNIRDSWEEVKLSTLTGVWKK 405


>gi|55956788 nucleolin [Homo sapiens]
          Length = 710

 Score = 87.4 bits (215), Expect = 3e-17
 Identities = 49/162 (30%), Positives = 85/162 (52%), Gaps = 16/162 (9%)

Query: 377 PSDIAACFREAGFGGGPNATITTSLKSEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEG 436
           P    A     G   G NA      K + +EEE+++ EE+EE+ E E+E+E+  E     
Sbjct: 122 PGKKGAAIPAKGAKNGKNAK-----KEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMK 176

Query: 437 GEGEELGEEEEVEEEGDVDSDEEEEEDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEA 496
                   E+E +E+ + D D++++E+++S  E +E          A G   A     +A
Sbjct: 177 AAAAAPASEDEDDEDDEDDEDDDDDEEDDSEEEAMET-------TPAKGKKAAKVVPVKA 229

Query: 497 QCPTLHFLEGGEDSDSDSEEEDDEEEDDEDEDDDDDEEDGDE 538
           +    +  E  ++ + D +E+DD++EDDED+DD+DDEE+ +E
Sbjct: 230 K----NVAEDEDEEEDDEDEDDDDDEDDEDDDDEDDEEEEEE 267



 Score = 55.8 bits (133), Expect = 1e-07
 Identities = 32/118 (27%), Positives = 61/118 (51%), Gaps = 14/118 (11%)

Query: 393 PNATITTSLKSEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELG--------- 443
           P A    +     E+E++E++E++E++ + EE++ E E  E    +G++           
Sbjct: 172 PAAMKAAAAAPASEDEDDEDDEDDEDDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKN 231

Query: 444 -----EEEEVEEEGDVDSDEEEEEDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEA 496
                +EEE +E+ D D DE++E+D++   E  E E+  + V EA G      A+++A
Sbjct: 232 VAEDEDEEEDDEDEDDDDDEDDEDDDDEDDEEEEEEEEEEPVKEAPGKRKKEMAKQKA 289



 Score = 55.5 bits (132), Expect = 1e-07
 Identities = 33/129 (25%), Positives = 60/129 (46%), Gaps = 24/129 (18%)

Query: 427 EEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEEEEDEESSSEGLEAEDWAQGVVEAGGS 486
           ++G     +G +  +  ++E+ +EE D DS+E+EE+DE+   +  E E  A     A   
Sbjct: 124 KKGAAIPAKGAKNGKNAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAA-- 181

Query: 487 FGAYGAQEEAQCPTLHFLEGGEDSDSDSEEEDDEEEDDEDEDDDDDEEDGDEVPVPSFGE 546
                                  +  D ++EDDE+++D+D+D++DD E+      P+ G+
Sbjct: 182 ----------------------PASEDEDDEDDEDDEDDDDDEEDDSEEEAMETTPAKGK 219

Query: 547 AMAYFAMVK 555
             A    VK
Sbjct: 220 KAAKVVPVK 228



 Score = 50.4 bits (119), Expect = 5e-06
 Identities = 36/169 (21%), Positives = 72/169 (42%), Gaps = 10/169 (5%)

Query: 391 GGPNATITTSLKSEGEEEEEEEEEEEEEEGEGEE---EEEEGEEEEEEGGEGEELGEEEE 447
           G P        + E + E+EE  E+EE++  GEE    +++G++      +   +   ++
Sbjct: 12  GDPKKMAPPPKEVEEDSEDEEMSEDEEDDSSGEEVVIPQKKGKKAAATSAKKVVVSPTKK 71

Query: 448 VEEEGDVDSDEEEEEDEESSSEGLEAEDWAQGVVEAGGSFGAYG-------AQEEAQCPT 500
           V               + +++   +    A+ V   G      G        ++ A  P 
Sbjct: 72  VAVATPAKKAAVTPGKKAAATPAKKTVTPAKAVTTPGKKGATPGKALVATPGKKGAAIPA 131

Query: 501 LHFLEGGEDSDSDSEEEDDEEEDDEDEDDDDDEEDGDEVPVPSFGEAMA 549
                G      DS+EE+D++ ++++EDD+D++ED DE+   +   A A
Sbjct: 132 KGAKNGKNAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAA 180



 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 21/70 (30%), Positives = 45/70 (64%)

Query: 403 SEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEEEE 462
           +E E+EEE++E+E++++ E +E++++ ++EEEE  E EE  +E   + + ++   +   E
Sbjct: 233 AEDEDEEEDDEDEDDDDDEDDEDDDDEDDEEEEEEEEEEPVKEAPGKRKKEMAKQKAAPE 292

Query: 463 DEESSSEGLE 472
            ++   EG E
Sbjct: 293 AKKQKVEGTE 302



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 17/67 (25%), Positives = 44/67 (65%)

Query: 402 KSEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEEE 461
           + + E+E+++++E++E++ + ++EEEE EEEEE   E     ++E  +++   ++ +++ 
Sbjct: 239 EEDDEDEDDDDDEDDEDDDDEDDEEEEEEEEEEPVKEAPGKRKKEMAKQKAAPEAKKQKV 298

Query: 462 EDEESSS 468
           E  E ++
Sbjct: 299 EGTEPTT 305



 Score = 38.9 bits (89), Expect = 0.014
 Identities = 17/61 (27%), Positives = 38/61 (62%)

Query: 414 EEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEEEEDEESSSEGLEA 473
           E+E+EE + E+E+++ +E++E+  + ++  EEEE EEE   ++  + +++        EA
Sbjct: 234 EDEDEEEDDEDEDDDDDEDDEDDDDEDDEEEEEEEEEEPVKEAPGKRKKEMAKQKAAPEA 293

Query: 474 E 474
           +
Sbjct: 294 K 294



 Score = 32.0 bits (71), Expect = 1.7
 Identities = 13/46 (28%), Positives = 26/46 (56%)

Query: 515 EEEDDEEEDDEDEDDDDDEEDGDEVPVPSFGEAMAYFAMVKRYLTS 560
           +E +++ ED+E  +D++D+  G+EV +P      A     K+ + S
Sbjct: 22  KEVEEDSEDEEMSEDEEDDSSGEEVVIPQKKGKKAAATSAKKVVVS 67


>gi|4759128 solute carrier family 24 (sodium/potassium/calcium
           exchanger), member 1 [Homo sapiens]
          Length = 1099

 Score = 84.3 bits (207), Expect = 3e-16
 Identities = 55/159 (34%), Positives = 85/159 (53%), Gaps = 31/159 (19%)

Query: 402 KSEGE---EEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVE--------- 449
           +S GE   EE E   E E EE  G E + EGE E E  G+GEE  +E E E         
Sbjct: 751 ESTGEMPGEEGETAGEGETEEKSGGETQPEGEGETETQGKGEECEDENEAEGKGDNEGED 810

Query: 450 ------EEGDVDSDEEEEEDEESSSEGL-EAEDWAQGVVEAGGSFGAYGAQEEAQCPTLH 502
                 E+G++  +E E E +E S+E   EA++  +GV + GGS G    +EE       
Sbjct: 811 EGEIHAEDGEMKGNEGETESQELSAENHGEAKNDEKGVEDGGGSDGGDSEEEE------- 863

Query: 503 FLEGGEDSDSDSEEEDDEEEDDEDEDDDDDEEDGDEVPV 541
                E+ +   EEE++EE+++E+E+++++EE G+E P+
Sbjct: 864 -----EEEEEQEEEEEEEEQEEEEEEEEEEEEKGNEEPL 897



 Score = 59.7 bits (143), Expect = 7e-09
 Identities = 49/177 (27%), Positives = 80/177 (45%), Gaps = 40/177 (22%)

Query: 402 KSEGEEEEEEEEE----------------EEEEEGEGEEEEEEGEEEEEEGGEGEELGEE 445
           K+E + EEEE  +                +++E   G+E+  E E   E  GE  E   E
Sbjct: 707 KAESKPEEEEPAKLPAVTVTPAPVPDIKGDQKENPGGQEDVAEAESTGEMPGEEGETAGE 766

Query: 446 EEVEEEGDVDSDEEEEEDEESSSEGLEAED--WAQGV---------------VEAGGSFG 488
            E EE+   ++  E E + E+  +G E ED   A+G                 E  G+ G
Sbjct: 767 GETEEKSGGETQPEGEGETETQGKGEECEDENEAEGKGDNEGEDEGEIHAEDGEMKGNEG 826

Query: 489 AYGAQE-------EAQCPTLHFLEGGEDSDSDSEEEDDEEEDDEDEDDDDDEEDGDE 538
              +QE       EA+       +GG     DSEEE++EEE+ E+E++++++E+ +E
Sbjct: 827 ETESQELSAENHGEAKNDEKGVEDGGGSDGGDSEEEEEEEEEQEEEEEEEEQEEEEE 883



 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 35/88 (39%), Positives = 48/88 (54%), Gaps = 7/88 (7%)

Query: 391 GGPNATITTSLKSEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEE 450
           G    T +  L +E   E + +E+  E+ G  +  + E EEEEEE  E EE  EEEE EE
Sbjct: 823 GNEGETESQELSAENHGEAKNDEKGVEDGGGSDGGDSEEEEEEEEEQEEEE--EEEEQEE 880

Query: 451 EGDVDSDEEEEEDEESSSEGLEAEDWAQ 478
           E     +EEEEE+EE  +E   + DW +
Sbjct: 881 E-----EEEEEEEEEKGNEEPLSLDWPE 903



 Score = 53.1 bits (126), Expect = 7e-07
 Identities = 36/111 (32%), Positives = 50/111 (45%), Gaps = 34/111 (30%)

Query: 393 PNATITTSLKSEGEEEEEEEEEEEEEEGEGEEEEE-----------EGEEEEEE------ 435
           P     T  + +GEE E+E E E + + EGE+E E           EGE E +E      
Sbjct: 779 PEGEGETETQGKGEECEDENEAEGKGDNEGEDEGEIHAEDGEMKGNEGETESQELSAENH 838

Query: 436 -----------------GGEGEELGEEEEVEEEGDVDSDEEEEEDEESSSE 469
                            GG+ EE  EEEE +EE + + ++EEEE+EE   E
Sbjct: 839 GEAKNDEKGVEDGGGSDGGDSEEEEEEEEEQEEEEEEEEQEEEEEEEEEEE 889



 Score = 46.2 bits (108), Expect = 9e-05
 Identities = 24/44 (54%), Positives = 27/44 (61%)

Query: 390 GGGPNATITTSLKSEGEEEEEEEEEEEEEEGEGEEEEEEGEEEE 433
           GG          + E E+EEEEEEEE+EEE E EEEEEE   EE
Sbjct: 852 GGSDGGDSEEEEEEEEEQEEEEEEEEQEEEEEEEEEEEEKGNEE 895



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 25/47 (53%), Positives = 31/47 (65%), Gaps = 1/47 (2%)

Query: 386 EAGFGGGPNATITTSLKSEGEEEEEEEEEEEEEEGEGEEEEEEGEEE 432
           + G   G ++      + E EEEEEEEE+EEEEE E EEEEE+G EE
Sbjct: 850 DGGGSDGGDSEEEEEEEEEQEEEEEEEEQEEEEE-EEEEEEEKGNEE 895


>gi|155030232 proline, glutamic acid and leucine rich protein 1 [Homo
            sapiens]
          Length = 1130

 Score = 82.0 bits (201), Expect = 1e-15
 Identities = 72/172 (41%), Positives = 84/172 (48%), Gaps = 18/172 (10%)

Query: 390  GGGPNA-----TI----TTSLKSEGEEEEEEEEEEEEEEGEGEEEEEEGEEEE-EEGGEG 439
            GGGP A     T+    ++  + E EEEEEEEEEEEEEE E  EEEEE EEE  EE  E 
Sbjct: 868  GGGPPALEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEE 927

Query: 440  EELGEEEEVEEEGDVDSDEEEEEDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCP 499
            EE  EEE  EEEG+++ +EEEEEDEE   E  E ED   G   AGG             P
Sbjct: 928  EEEFEEEFEEEEGELE-EEEEEEDEEEEEELEEVEDLEFGT--AGGEVEEGAPPPPTLPP 984

Query: 500  TLHFLEGGEDSDSDSEEE-----DDEEEDDEDEDDDDDEEDGDEVPVPSFGE 546
             L   E       + E E     + EE   E+E   D         +PS GE
Sbjct: 985  ALPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAPEALPSQGE 1036



 Score = 39.7 bits (91), Expect = 0.008
 Identities = 17/54 (31%), Positives = 34/54 (62%)

Query: 485 GSFGAYGAQEEAQCPTLHFLEGGEDSDSDSEEEDDEEEDDEDEDDDDDEEDGDE 538
           G+ G  G     +  T+  +   ++ + + EEE++EEE++E+E++D +EE+ DE
Sbjct: 864 GTPGGGGPPALEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDE 917



 Score = 36.2 bits (82), Expect = 0.088
 Identities = 50/203 (24%), Positives = 74/203 (36%), Gaps = 74/203 (36%)

Query: 402  KSEGEEEEEEEEEEEEEEGEGEEEE----------------------------------- 426
            + EGE EEEEEEE+EEEE E EE E                                   
Sbjct: 937  EEEGELEEEEEEEDEEEEEELEEVEDLEFGTAGGEVEEGAPPPPTLPPALPPPESPPKVQ 996

Query: 427  -------------EEGEEEEEEGGE------GEELGEEEEVEEEGDVDS----DEEEEED 463
                         EE   EEE G +       E L  + EVE EG+  +     +E  E+
Sbjct: 997  PEPEPEPGLLLEVEEPGTEEERGADTAPTLAPEALPSQGEVEREGESPAAGPPPQELVEE 1056

Query: 464  EESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHFLEGGEDSDSDSEEEDDEEED 523
            E S+   L  E+   G              ++ Q P     E   ++++++E   ++E+D
Sbjct: 1057 EPSAPPTLLEEETEDG-------------SDKVQPPPETPAEEEMETETEAEALQEKEQD 1103

Query: 524  DED---EDDDDDEEDGDEVPVPS 543
            D      D  D   D ++ P P+
Sbjct: 1104 DTAAMLADFIDCPPDDEKPPPPT 1126



 Score = 33.5 bits (75), Expect = 0.57
 Identities = 24/78 (30%), Positives = 39/78 (50%), Gaps = 10/78 (12%)

Query: 400  SLKSEGEEEEEEEEEEEEEEGEGEEEEEEG------EEEEEEGGE----GEELGEEEEVE 449
            +L S+GE E E E        +   EEE        EEE E+G +      E   EEE+E
Sbjct: 1030 ALPSQGEVEREGESPAAGPPPQELVEEEPSAPPTLLEEETEDGSDKVQPPPETPAEEEME 1089

Query: 450  EEGDVDSDEEEEEDEESS 467
             E + ++ +E+E+D+ ++
Sbjct: 1090 TETEAEALQEKEQDDTAA 1107



 Score = 32.3 bits (72), Expect = 1.3
 Identities = 36/141 (25%), Positives = 52/141 (36%), Gaps = 21/141 (14%)

Query: 393  PNATITTSLKSEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEG---EELGEEEE-- 447
            P   +   ++  G EEE   +       E    + E E E E    G   +EL EEE   
Sbjct: 1001 PEPGLLLEVEEPGTEEERGADTAPTLAPEALPSQGEVEREGESPAAGPPPQELVEEEPSA 1060

Query: 448  ----VEEEGDVDSDEEEEEDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHF 503
                +EEE +  SD+ +   E  + E +E E  A+ +            QE+ Q  T   
Sbjct: 1061 PPTLLEEETEDGSDKVQPPPETPAEEEMETETEAEAL------------QEKEQDDTAAM 1108

Query: 504  LEGGEDSDSDSEEEDDEEEDD 524
            L    D   D E+     E D
Sbjct: 1109 LADFIDCPPDDEKPPPPTEPD 1129


>gi|13540523 nucleosomal binding protein 1 [Homo sapiens]
          Length = 282

 Score = 79.0 bits (193), Expect = 1e-14
 Identities = 49/168 (29%), Positives = 90/168 (53%), Gaps = 18/168 (10%)

Query: 390 GGGPNATITTSLKSEGEEEEEEEEEEEEEEGEG--EEEEEEGEEEEEEGGEGEELGEEEE 447
           GG     +   +K+E E+++E+EE++ EE+GE   E+++E+GEE+ +E   G E GE+ +
Sbjct: 112 GGEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEAGKEDKDEKGEEDGKEDKNGNEKGEDAK 171

Query: 448 VEEEG--------------DVDSDEEEEEDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQ 493
            +E+G              +   DE+EEED + + +G E ED  +   +  G       +
Sbjct: 172 EKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKENEDGKEKGDKKEGK-DVKVKE 230

Query: 494 EEAQCPTLHFLEGGEDSDSDSEEED-DEEEDDEDEDDDDDEEDGDEVP 540
           +E +       EGG + ++  E+ED  EEE+ ++ED+  +++   E P
Sbjct: 231 DEKEREDGKEDEGGNEEEAGKEKEDLKEEEEGKEEDEIKEDDGKKEEP 278



 Score = 60.8 bits (146), Expect = 3e-09
 Identities = 46/171 (26%), Positives = 79/171 (46%), Gaps = 29/171 (16%)

Query: 394 NATITTSLKSEGEEEEEEEEEEEEEEGEGEEE--------------EEEGEEEEEEGGEG 439
           N    T    E +E    E + EEE+ + +EE              +E+GEE+ +E   G
Sbjct: 104 NIEDATEKGGEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEAGKEDKDEKGEEDGKEDKNG 163

Query: 440 EELGEEEEVEEEG--------------DVDSDEEEEEDEESSSEGLEAEDWAQGVVEAGG 485
            E GE+ + +E+G              +   DE+EEED + + +G E ED  +   +  G
Sbjct: 164 NEKGEDAKEKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKENEDGKEKGDKKEG 223

Query: 486 SFGAYGAQEEAQCPTLHFLEGGEDSDSDSEEEDDEEEDDEDEDDDDDEEDG 536
                  ++E +       EGG + ++  E+ED +EE++  E+D+  E+DG
Sbjct: 224 K-DVKVKEDEKEREDGKEDEGGNEEEAGKEKEDLKEEEEGKEEDEIKEDDG 273



 Score = 59.3 bits (142), Expect = 1e-08
 Identities = 39/145 (26%), Positives = 71/145 (48%), Gaps = 10/145 (6%)

Query: 395 ATITTSLKSEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDV 454
           A IT +  SE E  E +EE  E+   +G E++E    E +   E ++  EE++ EE+G+ 
Sbjct: 85  AKITEAPASEKEIVEVKEENIEDATEKGGEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEA 144

Query: 455 DSDEEEEEDEESSSEGLEAEDWAQGVVE-AGGSFGAYGAQEEAQCPTLHFLEGGEDSDSD 513
             ++++E+ EE   E     +  +   E   G  G  G             E G++   D
Sbjct: 145 GKEDKDEKGEEDGKEDKNGNEKGEDAKEKEDGKKGEDGKGNG---------EDGKEKGED 195

Query: 514 SEEEDDEEEDDEDEDDDDDEEDGDE 538
            +EE+D +E  + ++++D +E GD+
Sbjct: 196 EKEEEDRKETGDGKENEDGKEKGDK 220



 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 27/65 (41%), Positives = 45/65 (69%), Gaps = 4/65 (6%)

Query: 402 KSEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEEE 461
           K EG++ + +E+E+E E+G+    E+EG  EEE G E E+L EEEE +EE ++  D+ ++
Sbjct: 220 KKEGKDVKVKEDEKEREDGK----EDEGGNEEEAGKEKEDLKEEEEGKEEDEIKEDDGKK 275

Query: 462 EDEES 466
           E+ +S
Sbjct: 276 EEPQS 280



 Score = 52.8 bits (125), Expect = 9e-07
 Identities = 42/162 (25%), Positives = 70/162 (43%), Gaps = 17/162 (10%)

Query: 394 NATITTSLKSEGEEEE--EEEEEEEEEEGEG-------------EEEEEEGEEEEEEGGE 438
           N   +    +E ++E   EE+  E  + GE              E +EE  E+  E+GGE
Sbjct: 55  NIDTSAQAVAETKQEAVVEEDYNENAKNGEAKITEAPASEKEIVEVKEENIEDATEKGGE 114

Query: 439 GEELGEEEEVEEEGDVDSDEEEEEDE--ESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEA 496
            +E    E   EE D   DEE++ +E  E+  E  + +    G  +  G+     A+E+ 
Sbjct: 115 KKEAVAAEVKNEEEDQKEDEEDQNEEKGEAGKEDKDEKGEEDGKEDKNGNEKGEDAKEKE 174

Query: 497 QCPTLHFLEGGEDSDSDSEEEDDEEEDDEDEDDDDDEEDGDE 538
                   +G  +   +  E++ EEED ++  D  + EDG E
Sbjct: 175 DGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKENEDGKE 216



 Score = 50.1 bits (118), Expect = 6e-06
 Identities = 36/104 (34%), Positives = 55/104 (52%), Gaps = 21/104 (20%)

Query: 386 EAGFGGGPNATITTSLKSEGEEEEEEEEEEEEEEG-EGEEEEEEGE------------EE 432
           E G G G +       K +GE+E+EEE+ +E  +G E E+ +E+G+            E+
Sbjct: 180 EDGKGNGEDG------KEKGEDEKEEEDRKETGDGKENEDGKEKGDKKEGKDVKVKEDEK 233

Query: 433 EEEGGEGEELGEEEEVEEEGDVDSDEEE--EEDEESSSEGLEAE 474
           E E G+ +E G EEE  +E +   +EEE  EEDE    +G + E
Sbjct: 234 EREDGKEDEGGNEEEAGKEKEDLKEEEEGKEEDEIKEDDGKKEE 277



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 23/75 (30%), Positives = 48/75 (64%), Gaps = 7/75 (9%)

Query: 404 EGEEEEEEEEEEEEEEGEG----EEEEEEGEEEEEEGGEGEELGEEEE---VEEEGDVDS 456
           +G+E E+ +E+ +++EG+     E+E+E  + +E+EGG  EE G+E+E    EEEG  + 
Sbjct: 207 DGKENEDGKEKGDKKEGKDVKVKEDEKEREDGKEDEGGNEEEAGKEKEDLKEEEEGKEED 266

Query: 457 DEEEEEDEESSSEGL 471
           + +E++ ++   + +
Sbjct: 267 EIKEDDGKKEEPQSI 281


>gi|13569879 acidic (leucine-rich) nuclear phosphoprotein 32 family,
           member E isoform 1 [Homo sapiens]
          Length = 268

 Score = 75.9 bits (185), Expect = 1e-13
 Identities = 56/148 (37%), Positives = 76/148 (51%), Gaps = 34/148 (22%)

Query: 399 TSLKSEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDE 458
           T L    +E+ E  + EEE++ +G+E++E  EEEE E G  E  G EEE EEE + D DE
Sbjct: 143 TYLDGFDQEDNEAPDSEEEDDEDGDEDDE--EEEENEAGPPE--GYEEEEEEEEEEDEDE 198

Query: 459 EEEEDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHFLEGGEDSDSDSEEED 518
           +E+EDE  S  G       +G  E G S   Y  +EE Q          E+ D D  EE 
Sbjct: 199 DEDEDEAGSELG-------EGEEEVGLS---YLMKEEIQ---------DEEDDDDYVEEG 239

Query: 519 DEEEDDE-----------DEDDDDDEED 535
           +EEE++E           D +DD +EED
Sbjct: 240 EEEEEEEEGGLRGEKRKRDAEDDGEEED 267



 Score = 75.1 bits (183), Expect = 2e-13
 Identities = 52/144 (36%), Positives = 75/144 (52%), Gaps = 33/144 (22%)

Query: 404 EGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEEEED 463
           +G ++E+ E  + EEE + + +E++ EEEE E G  E  G EEE EEE + D DE+E+ED
Sbjct: 146 DGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPE--GYEEEEEEEEEEDEDEDEDED 203

Query: 464 EESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHFLEGGEDSDSDSEEEDDEEED 523
           E  S  G       +G  E G S   Y  +EE Q          E+ D D  EE +EEE+
Sbjct: 204 EAGSELG-------EGEEEVGLS---YLMKEEIQ---------DEEDDDDYVEEGEEEEE 244

Query: 524 DED------------EDDDDDEED 535
           +E+            EDD ++E+D
Sbjct: 245 EEEGGLRGEKRKRDAEDDGEEEDD 268



 Score = 46.2 bits (108), Expect = 9e-05
 Identities = 32/103 (31%), Positives = 47/103 (45%), Gaps = 33/103 (32%)

Query: 437 GEGEELGEEEEVEEEGDVDSDEEEEEDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEA 496
           G  +E  E  + EEE D D DE++EE+EE+               EAG            
Sbjct: 147 GFDQEDNEAPDSEEEDDEDGDEDDEEEEEN---------------EAGPP---------- 181

Query: 497 QCPTLHFLEGGEDSDSDSEEEDDEEEDDEDEDDDDDEEDGDEV 539
                   EG E+ + + EEED++E++DEDE   +  E  +EV
Sbjct: 182 --------EGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEV 216



 Score = 40.8 bits (94), Expect = 0.004
 Identities = 19/40 (47%), Positives = 27/40 (67%), Gaps = 2/40 (5%)

Query: 503 FLEGGEDSDSDSEEEDDEEEDDEDEDDDDDEEDGDEVPVP 542
           +L+G +  D+  E  D EEEDDED D+DD+EE+ +E   P
Sbjct: 144 YLDGFDQEDN--EAPDSEEEDDEDGDEDDEEEEENEAGPP 181


>gi|210147569 acidic (leucine-rich) nuclear phosphoprotein 32
           family, member E isoform 2 [Homo sapiens]
          Length = 227

 Score = 75.9 bits (185), Expect = 1e-13
 Identities = 56/148 (37%), Positives = 76/148 (51%), Gaps = 34/148 (22%)

Query: 399 TSLKSEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDE 458
           T L    +E+ E  + EEE++ +G+E++E  EEEE E G  E  G EEE EEE + D DE
Sbjct: 102 TYLDGFDQEDNEAPDSEEEDDEDGDEDDE--EEEENEAGPPE--GYEEEEEEEEEEDEDE 157

Query: 459 EEEEDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHFLEGGEDSDSDSEEED 518
           +E+EDE  S  G       +G  E G S   Y  +EE Q          E+ D D  EE 
Sbjct: 158 DEDEDEAGSELG-------EGEEEVGLS---YLMKEEIQ---------DEEDDDDYVEEG 198

Query: 519 DEEEDDE-----------DEDDDDDEED 535
           +EEE++E           D +DD +EED
Sbjct: 199 EEEEEEEEGGLRGEKRKRDAEDDGEEED 226



 Score = 75.1 bits (183), Expect = 2e-13
 Identities = 52/144 (36%), Positives = 75/144 (52%), Gaps = 33/144 (22%)

Query: 404 EGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEEEED 463
           +G ++E+ E  + EEE + + +E++ EEEE E G  E  G EEE EEE + D DE+E+ED
Sbjct: 105 DGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPE--GYEEEEEEEEEEDEDEDEDED 162

Query: 464 EESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHFLEGGEDSDSDSEEEDDEEED 523
           E  S  G       +G  E G S   Y  +EE Q          E+ D D  EE +EEE+
Sbjct: 163 EAGSELG-------EGEEEVGLS---YLMKEEIQ---------DEEDDDDYVEEGEEEEE 203

Query: 524 DED------------EDDDDDEED 535
           +E+            EDD ++E+D
Sbjct: 204 EEEGGLRGEKRKRDAEDDGEEEDD 227



 Score = 46.2 bits (108), Expect = 9e-05
 Identities = 32/103 (31%), Positives = 47/103 (45%), Gaps = 33/103 (32%)

Query: 437 GEGEELGEEEEVEEEGDVDSDEEEEEDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEA 496
           G  +E  E  + EEE D D DE++EE+EE+               EAG            
Sbjct: 106 GFDQEDNEAPDSEEEDDEDGDEDDEEEEEN---------------EAGPP---------- 140

Query: 497 QCPTLHFLEGGEDSDSDSEEEDDEEEDDEDEDDDDDEEDGDEV 539
                   EG E+ + + EEED++E++DEDE   +  E  +EV
Sbjct: 141 --------EGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEV 175



 Score = 40.8 bits (94), Expect = 0.004
 Identities = 19/40 (47%), Positives = 27/40 (67%), Gaps = 2/40 (5%)

Query: 503 FLEGGEDSDSDSEEEDDEEEDDEDEDDDDDEEDGDEVPVP 542
           +L+G +  D+  E  D EEEDDED D+DD+EE+ +E   P
Sbjct: 103 YLDGFDQEDN--EAPDSEEEDDEDGDEDDEEEEENEAGPP 140


>gi|210147571 acidic (leucine-rich) nuclear phosphoprotein 32
           family, member E isoform 3 [Homo sapiens]
          Length = 220

 Score = 75.9 bits (185), Expect = 1e-13
 Identities = 56/148 (37%), Positives = 76/148 (51%), Gaps = 34/148 (22%)

Query: 399 TSLKSEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDE 458
           T L    +E+ E  + EEE++ +G+E++E  EEEE E G  E  G EEE EEE + D DE
Sbjct: 95  TYLDGFDQEDNEAPDSEEEDDEDGDEDDE--EEEENEAGPPE--GYEEEEEEEEEEDEDE 150

Query: 459 EEEEDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHFLEGGEDSDSDSEEED 518
           +E+EDE  S  G       +G  E G S   Y  +EE Q          E+ D D  EE 
Sbjct: 151 DEDEDEAGSELG-------EGEEEVGLS---YLMKEEIQ---------DEEDDDDYVEEG 191

Query: 519 DEEEDDE-----------DEDDDDDEED 535
           +EEE++E           D +DD +EED
Sbjct: 192 EEEEEEEEGGLRGEKRKRDAEDDGEEED 219



 Score = 75.1 bits (183), Expect = 2e-13
 Identities = 52/144 (36%), Positives = 75/144 (52%), Gaps = 33/144 (22%)

Query: 404 EGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEEEED 463
           +G ++E+ E  + EEE + + +E++ EEEE E G  E  G EEE EEE + D DE+E+ED
Sbjct: 98  DGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPE--GYEEEEEEEEEEDEDEDEDED 155

Query: 464 EESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHFLEGGEDSDSDSEEEDDEEED 523
           E  S  G       +G  E G S   Y  +EE Q          E+ D D  EE +EEE+
Sbjct: 156 EAGSELG-------EGEEEVGLS---YLMKEEIQ---------DEEDDDDYVEEGEEEEE 196

Query: 524 DED------------EDDDDDEED 535
           +E+            EDD ++E+D
Sbjct: 197 EEEGGLRGEKRKRDAEDDGEEEDD 220



 Score = 46.2 bits (108), Expect = 9e-05
 Identities = 32/103 (31%), Positives = 47/103 (45%), Gaps = 33/103 (32%)

Query: 437 GEGEELGEEEEVEEEGDVDSDEEEEEDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEA 496
           G  +E  E  + EEE D D DE++EE+EE+               EAG            
Sbjct: 99  GFDQEDNEAPDSEEEDDEDGDEDDEEEEEN---------------EAGPP---------- 133

Query: 497 QCPTLHFLEGGEDSDSDSEEEDDEEEDDEDEDDDDDEEDGDEV 539
                   EG E+ + + EEED++E++DEDE   +  E  +EV
Sbjct: 134 --------EGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEV 168



 Score = 40.8 bits (94), Expect = 0.004
 Identities = 19/40 (47%), Positives = 27/40 (67%), Gaps = 2/40 (5%)

Query: 503 FLEGGEDSDSDSEEEDDEEEDDEDEDDDDDEEDGDEVPVP 542
           +L+G +  D+  E  D EEEDDED D+DD+EE+ +E   P
Sbjct: 96  YLDGFDQEDN--EAPDSEEEDDEDGDEDDEEEEENEAGPP 133


>gi|28274705 family with sequence similarity 9, member A [Homo
           sapiens]
          Length = 332

 Score = 74.7 bits (182), Expect = 2e-13
 Identities = 48/103 (46%), Positives = 59/103 (57%), Gaps = 5/103 (4%)

Query: 376 EPSDIAACFREAGFGGGPNATITTSLKSEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEE 435
           E ++ AA   EA       A     +  E EEEEE+EEEEE+EE E E EEE G EE EE
Sbjct: 192 EEAEAAAAAAEAAAAAEAAAAAAEVIVVEDEEEEEKEEEEEKEEEEEEGEEEGGGEEGEE 251

Query: 436 GGEGEELGEEEEVEEEGDVDSDEEEEEDEESSSEGLEAEDWAQ 478
           GG G E GEE E EEE     +EEEEE+E+  +   + + W Q
Sbjct: 252 GGGGGE-GEETEEEEE----EEEEEEEEEQIKAFQEKQKRWQQ 289



 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 35/120 (29%), Positives = 55/120 (45%), Gaps = 29/120 (24%)

Query: 410 EEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEEL--GEEEEVEEEGDVDSDEEEEEDEESS 467
           E+++++E EE E      E     E      E+   E+EE EE+ + +  EEEEE+ E  
Sbjct: 184 EKQKDDEAEEAEAAAAAAEAAAAAEAAAAAAEVIVVEDEEEEEKEEEEEKEEEEEEGEEE 243

Query: 468 SEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHFLEGGEDSDSDSEEEDDEEEDDEDE 527
             G E E       E GG                    GGE  +++ EEE++EEE++E++
Sbjct: 244 GGGEEGE-------EGGG--------------------GGEGEETEEEEEEEEEEEEEEQ 276



 Score = 37.0 bits (84), Expect = 0.052
 Identities = 25/66 (37%), Positives = 33/66 (50%), Gaps = 8/66 (12%)

Query: 386 EAGFGGGPNATITTSLKSEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEE 445
           E G GGG           E EEEEEEEEEEEEEE     +E++   ++  G     L E 
Sbjct: 250 EEGGGGGEG--------EETEEEEEEEEEEEEEEQIKAFQEKQKRWQQPTGVRSWRLREM 301

Query: 446 EEVEEE 451
           + + E+
Sbjct: 302 KPLLEQ 307



 Score = 34.3 bits (77), Expect = 0.34
 Identities = 20/79 (25%), Positives = 37/79 (46%), Gaps = 9/79 (11%)

Query: 458 EEEEEDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHFLEGGEDSDSDSEEE 517
           E++++DE   +E   A   A    EA  +       E+         E  E+ + + E+E
Sbjct: 184 EKQKDDEAEEAEAAAAAAEAAAAAEAAAAAAEVIVVED---------EEEEEKEEEEEKE 234

Query: 518 DDEEEDDEDEDDDDDEEDG 536
           ++EEE +E+   ++ EE G
Sbjct: 235 EEEEEGEEEGGGEEGEEGG 253



 Score = 33.9 bits (76), Expect = 0.44
 Identities = 23/104 (22%), Positives = 47/104 (45%), Gaps = 24/104 (23%)

Query: 458 EEEEEDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHFLEGGEDSDSDSEEE 517
           ++E E+ E+++   EA   A+    A         +EE         E  E+ + + EEE
Sbjct: 188 DDEAEEAEAAAAAAEAAAAAEAAAAAAEVIVVEDEEEE---------EKEEEEEKEEEEE 238

Query: 518 DDEEE---------------DDEDEDDDDDEEDGDEVPVPSFGE 546
           + EEE               ++ +E+++++EE+ +E  + +F E
Sbjct: 239 EGEEEGGGEEGEEGGGGGEGEETEEEEEEEEEEEEEEQIKAFQE 282


>gi|17975763 myelin transcription factor 1 [Homo sapiens]
          Length = 1121

 Score = 74.3 bits (181), Expect = 3e-13
 Identities = 47/137 (34%), Positives = 69/137 (50%), Gaps = 8/137 (5%)

Query: 394 NATITTSLKSEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGD 453
           +A    S K +G    EEE+EEEEEE E EEE+EE EEEEEE        EEEE EEE +
Sbjct: 242 DAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEE-------EEEEEEEEEEE 294

Query: 454 VDSDEEEEEDEESSSEGLEAEDWAQGVVEAGGSF-GAYGAQEEAQCPTLHFLEGGEDSDS 512
            + +EEEEE+EE++ + +  ED +    +      G      + +   +  +   +D D 
Sbjct: 295 EEEEEEEEEEEEAAPDVIFQEDTSHTSAQKAPELRGPESPSPKPEYSVIVEVRSDDDKDE 354

Query: 513 DSEEEDDEEEDDEDEDD 529
           D+        D+ +  D
Sbjct: 355 DTHSRKSTVTDESEMQD 371



 Score = 56.2 bits (134), Expect = 8e-08
 Identities = 49/212 (23%), Positives = 88/212 (41%), Gaps = 41/212 (19%)

Query: 333 VKGHYRQAMLLKAMAALEGQDPSGLQLGLTEALHFVAAAWQAVEPSDIAACFREAGFGGG 392
           VK H+    +  A A+ +G   S   +  T  L+    A + +   D+    +      G
Sbjct: 137 VKSHFGSNPIGSATASSKGSYSSYQGIIATSLLNLGQIAEETLVEEDLGQAAKP-----G 191

Query: 393 PNATITTSLKSEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEE--GGEGEELGEEEEVEE 450
           P         +EG   EE E+    +  + EE  E   E  ++      E+   EE  ++
Sbjct: 192 PGIVHLLQEAAEGAASEEGEKGLFIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQ 251

Query: 451 EGDVDSDEEEEEDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHFLEGGEDS 510
           +G +  +EE+EE+EE   E  E ED                                E+ 
Sbjct: 252 KGILSHEEEDEEEEEEEEE--EEED--------------------------------EEE 277

Query: 511 DSDSEEEDDEEEDDEDEDDDDDEEDGDEVPVP 542
           + + EEE++EEE++E+E+++++EE+ +E   P
Sbjct: 278 EEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAP 309



 Score = 33.5 bits (75), Expect = 0.57
 Identities = 23/83 (27%), Positives = 37/83 (44%)

Query: 402 KSEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEEE 461
           + E EEEEEEEEE   +    E+      ++  E    E    + E     +V SD++++
Sbjct: 294 EEEEEEEEEEEEEAAPDVIFQEDTSHTSAQKAPELRGPESPSPKPEYSVIVEVRSDDDKD 353

Query: 462 EDEESSSEGLEAEDWAQGVVEAG 484
           ED  S    +  E   Q ++  G
Sbjct: 354 EDTHSRKSTVTDESEMQDMMTRG 376


>gi|5454088 acidic (leucine-rich) nuclear phosphoprotein 32 family,
           member B [Homo sapiens]
          Length = 251

 Score = 74.3 bits (181), Expect = 3e-13
 Identities = 46/132 (34%), Positives = 67/132 (50%), Gaps = 27/132 (20%)

Query: 404 EGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEEEED 463
           +G + E++E  + + E +G +EEEE EE E+E  E +E GEEEE +EE D D D E +ED
Sbjct: 146 DGYDREDQEAPDSDAEVDGVDEEEEDEEGEDEEDEDDEDGEEEEFDEEDDEDEDVEGDED 205

Query: 464 EESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHFLEGGEDSDSDSEEEDDEEED 523
           ++  SE  E E+              +G  EE            ED D D EEE+  + +
Sbjct: 206 DDEVSE--EEEE--------------FGLDEE-----------DEDEDEDEEEEEGGKGE 238

Query: 524 DEDEDDDDDEED 535
               + DD+ ED
Sbjct: 239 KRKRETDDEGED 250



 Score = 60.5 bits (145), Expect = 4e-09
 Identities = 34/79 (43%), Positives = 49/79 (62%), Gaps = 5/79 (6%)

Query: 402 KSEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGE-GEELGEEEEV----EEEGDVDS 456
           + E EE E+EE+E++E+  E E +EE+ E+E+ EG E  +E+ EEEE     EE+ D D 
Sbjct: 168 EEEDEEGEDEEDEDDEDGEEEEFDEEDDEDEDVEGDEDDDEVSEEEEEFGLDEEDEDEDE 227

Query: 457 DEEEEEDEESSSEGLEAED 475
           DEEEEE  +      E +D
Sbjct: 228 DEEEEEGGKGEKRKRETDD 246



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 34/102 (33%), Positives = 46/102 (45%), Gaps = 38/102 (37%)

Query: 438 EGEELGEEEEVEEEGDVDSDEEEEEDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQ 497
           +G +  ++E  + + +VD  +EEEEDEE   E  E ED                      
Sbjct: 146 DGYDREDQEAPDSDAEVDGVDEEEEDEEGEDE--EDED---------------------- 181

Query: 498 CPTLHFLEGGEDSDSDSEEEDDEEEDDEDEDDDDDEEDGDEV 539
                        D D EEE+ +EEDDEDED + DE+D DEV
Sbjct: 182 -------------DEDGEEEEFDEEDDEDEDVEGDEDD-DEV 209



 Score = 39.7 bits (91), Expect = 0.008
 Identities = 17/39 (43%), Positives = 29/39 (74%), Gaps = 1/39 (2%)

Query: 504 LEGGEDSDSDSEEEDDEEEDDED-EDDDDDEEDGDEVPV 541
           ++G ++ + D E ED+E+EDDED E+++ DEED ++  V
Sbjct: 162 VDGVDEEEEDEEGEDEEDEDDEDGEEEEFDEEDDEDEDV 200



 Score = 35.4 bits (80), Expect = 0.15
 Identities = 17/53 (32%), Positives = 32/53 (60%), Gaps = 5/53 (9%)

Query: 499 PTLHFLEG-----GEDSDSDSEEEDDEEEDDEDEDDDDDEEDGDEVPVPSFGE 546
           P L +L+G      E  DSD+E +  +EE++++E +D+++ED ++     F E
Sbjct: 140 PQLTYLDGYDREDQEAPDSDAEVDGVDEEEEDEEGEDEEDEDDEDGEEEEFDE 192


>gi|115529449 upstream binding transcription factor, RNA polymerase
           I isoform b [Homo sapiens]
          Length = 727

 Score = 72.4 bits (176), Expect = 1e-12
 Identities = 35/96 (36%), Positives = 61/96 (63%), Gaps = 8/96 (8%)

Query: 392 GPNATIT-TSLKSEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEE--- 447
           GPN   + T+L+S+ E EE++EE+E++E+ + EEE++E  +  E+GG+  E   E+E   
Sbjct: 624 GPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESED 683

Query: 448 ----VEEEGDVDSDEEEEEDEESSSEGLEAEDWAQG 479
                E++ D D DE+++EDE++ SEG  +   + G
Sbjct: 684 GDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSG 719



 Score = 62.0 bits (149), Expect = 2e-09
 Identities = 32/104 (30%), Positives = 55/104 (52%), Gaps = 23/104 (22%)

Query: 444 EEEEVEEEGDVDSDEEEEEDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHF 503
           EE++ E+E D D DEEEE+DE   S             E GG      +++E+       
Sbjct: 641 EEDDEEDEDDEDEDEEEEDDENGDSS------------EDGGDSSESSSEDES------- 681

Query: 504 LEGGEDSDSDSEEEDDEEEDDEDEDDDDDEEDGDEVPVPSFGEA 547
               ED D + E+++DE++D++D++D+D+E +G      S G++
Sbjct: 682 ----EDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDS 721



 Score = 55.8 bits (133), Expect = 1e-07
 Identities = 29/86 (33%), Positives = 51/86 (59%), Gaps = 11/86 (12%)

Query: 448 VEEEGDVDSDEEEEEDEESSSEGLEAEDWAQG-VVEAGGSFGAYGAQEEAQCPTLHFLEG 506
           ++ + + + D+EE+ED+E   E  E ED   G   E GG      +++E+        E 
Sbjct: 634 LQSKSESEEDDEEDEDDEDEDE--EEEDDENGDSSEDGGDSSESSSEDES--------ED 683

Query: 507 GEDSDSDSEEEDDEEEDDEDEDDDDD 532
           G++++ D E+EDD+E+DDEDED++ +
Sbjct: 684 GDENEEDDEDEDDDEDDDEDEDNESE 709



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 18/29 (62%), Positives = 27/29 (93%), Gaps = 1/29 (3%)

Query: 510 SDSDSEEEDDEEEDDEDED-DDDDEEDGD 537
           S S+SEE+D+E+EDDEDED +++D+E+GD
Sbjct: 636 SKSESEEDDEEDEDDEDEDEEEEDDENGD 664



 Score = 40.0 bits (92), Expect = 0.006
 Identities = 15/48 (31%), Positives = 29/48 (60%)

Query: 491 GAQEEAQCPTLHFLEGGEDSDSDSEEEDDEEEDDEDEDDDDDEEDGDE 538
           G   ++   TL      E+ D + E+++DE+E++ED+++ D  EDG +
Sbjct: 624 GPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGD 671



 Score = 37.7 bits (86), Expect = 0.030
 Identities = 14/51 (27%), Positives = 29/51 (56%)

Query: 403 SEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGD 453
           SE E E+ +E EE++E+ + +E+++E E+ E EG         +  + + +
Sbjct: 677 SEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 727



 Score = 36.6 bits (83), Expect = 0.068
 Identities = 19/56 (33%), Positives = 31/56 (55%), Gaps = 4/56 (7%)

Query: 403 SEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGD-VDSD 457
           SE   E+E E+ +E EE + +E+++E ++E+E   + E  G        GD  DSD
Sbjct: 673 SESSSEDESEDGDENEEDDEDEDDDEDDDEDE---DNESEGSSSSSSSSGDSSDSD 725



 Score = 32.0 bits (71), Expect = 1.7
 Identities = 14/42 (33%), Positives = 26/42 (61%), Gaps = 2/42 (4%)

Query: 390 GGGPNATITTSLKSEGEEEEE--EEEEEEEEEGEGEEEEEEG 429
           GG  + + +     +G+E EE  E+E+++E++ E E+ E EG
Sbjct: 669 GGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEG 710



 Score = 30.0 bits (66), Expect = 6.3
 Identities = 11/35 (31%), Positives = 21/35 (60%)

Query: 504 LEGGEDSDSDSEEEDDEEEDDEDEDDDDDEEDGDE 538
           L G     S +  +   E +++DE+D+DDE++ +E
Sbjct: 622 LRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEE 656


>gi|115529451 upstream binding transcription factor, RNA polymerase
           I isoform b [Homo sapiens]
          Length = 727

 Score = 72.4 bits (176), Expect = 1e-12
 Identities = 35/96 (36%), Positives = 61/96 (63%), Gaps = 8/96 (8%)

Query: 392 GPNATIT-TSLKSEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEE--- 447
           GPN   + T+L+S+ E EE++EE+E++E+ + EEE++E  +  E+GG+  E   E+E   
Sbjct: 624 GPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESED 683

Query: 448 ----VEEEGDVDSDEEEEEDEESSSEGLEAEDWAQG 479
                E++ D D DE+++EDE++ SEG  +   + G
Sbjct: 684 GDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSG 719



 Score = 62.0 bits (149), Expect = 2e-09
 Identities = 32/104 (30%), Positives = 55/104 (52%), Gaps = 23/104 (22%)

Query: 444 EEEEVEEEGDVDSDEEEEEDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHF 503
           EE++ E+E D D DEEEE+DE   S             E GG      +++E+       
Sbjct: 641 EEDDEEDEDDEDEDEEEEDDENGDSS------------EDGGDSSESSSEDES------- 681

Query: 504 LEGGEDSDSDSEEEDDEEEDDEDEDDDDDEEDGDEVPVPSFGEA 547
               ED D + E+++DE++D++D++D+D+E +G      S G++
Sbjct: 682 ----EDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDS 721



 Score = 55.8 bits (133), Expect = 1e-07
 Identities = 29/86 (33%), Positives = 51/86 (59%), Gaps = 11/86 (12%)

Query: 448 VEEEGDVDSDEEEEEDEESSSEGLEAEDWAQG-VVEAGGSFGAYGAQEEAQCPTLHFLEG 506
           ++ + + + D+EE+ED+E   E  E ED   G   E GG      +++E+        E 
Sbjct: 634 LQSKSESEEDDEEDEDDEDEDE--EEEDDENGDSSEDGGDSSESSSEDES--------ED 683

Query: 507 GEDSDSDSEEEDDEEEDDEDEDDDDD 532
           G++++ D E+EDD+E+DDEDED++ +
Sbjct: 684 GDENEEDDEDEDDDEDDDEDEDNESE 709



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 18/29 (62%), Positives = 27/29 (93%), Gaps = 1/29 (3%)

Query: 510 SDSDSEEEDDEEEDDEDED-DDDDEEDGD 537
           S S+SEE+D+E+EDDEDED +++D+E+GD
Sbjct: 636 SKSESEEDDEEDEDDEDEDEEEEDDENGD 664



 Score = 40.0 bits (92), Expect = 0.006
 Identities = 15/48 (31%), Positives = 29/48 (60%)

Query: 491 GAQEEAQCPTLHFLEGGEDSDSDSEEEDDEEEDDEDEDDDDDEEDGDE 538
           G   ++   TL      E+ D + E+++DE+E++ED+++ D  EDG +
Sbjct: 624 GPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGD 671



 Score = 37.7 bits (86), Expect = 0.030
 Identities = 14/51 (27%), Positives = 29/51 (56%)

Query: 403 SEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGD 453
           SE E E+ +E EE++E+ + +E+++E E+ E EG         +  + + +
Sbjct: 677 SEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 727



 Score = 36.6 bits (83), Expect = 0.068
 Identities = 19/56 (33%), Positives = 31/56 (55%), Gaps = 4/56 (7%)

Query: 403 SEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGD-VDSD 457
           SE   E+E E+ +E EE + +E+++E ++E+E   + E  G        GD  DSD
Sbjct: 673 SESSSEDESEDGDENEEDDEDEDDDEDDDEDE---DNESEGSSSSSSSSGDSSDSD 725



 Score = 32.0 bits (71), Expect = 1.7
 Identities = 14/42 (33%), Positives = 26/42 (61%), Gaps = 2/42 (4%)

Query: 390 GGGPNATITTSLKSEGEEEEE--EEEEEEEEEGEGEEEEEEG 429
           GG  + + +     +G+E EE  E+E+++E++ E E+ E EG
Sbjct: 669 GGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEG 710



 Score = 30.0 bits (66), Expect = 6.3
 Identities = 11/35 (31%), Positives = 21/35 (60%)

Query: 504 LEGGEDSDSDSEEEDDEEEDDEDEDDDDDEEDGDE 538
           L G     S +  +   E +++DE+D+DDE++ +E
Sbjct: 622 LRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEE 656


>gi|7657671 upstream binding transcription factor, RNA polymerase I
           isoform a [Homo sapiens]
          Length = 764

 Score = 72.4 bits (176), Expect = 1e-12
 Identities = 35/96 (36%), Positives = 61/96 (63%), Gaps = 8/96 (8%)

Query: 392 GPNATIT-TSLKSEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEE--- 447
           GPN   + T+L+S+ E EE++EE+E++E+ + EEE++E  +  E+GG+  E   E+E   
Sbjct: 661 GPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESED 720

Query: 448 ----VEEEGDVDSDEEEEEDEESSSEGLEAEDWAQG 479
                E++ D D DE+++EDE++ SEG  +   + G
Sbjct: 721 GDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSG 756



 Score = 62.0 bits (149), Expect = 2e-09
 Identities = 32/104 (30%), Positives = 55/104 (52%), Gaps = 23/104 (22%)

Query: 444 EEEEVEEEGDVDSDEEEEEDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHF 503
           EE++ E+E D D DEEEE+DE   S             E GG      +++E+       
Sbjct: 678 EEDDEEDEDDEDEDEEEEDDENGDSS------------EDGGDSSESSSEDES------- 718

Query: 504 LEGGEDSDSDSEEEDDEEEDDEDEDDDDDEEDGDEVPVPSFGEA 547
               ED D + E+++DE++D++D++D+D+E +G      S G++
Sbjct: 719 ----EDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDS 758



 Score = 55.8 bits (133), Expect = 1e-07
 Identities = 29/86 (33%), Positives = 51/86 (59%), Gaps = 11/86 (12%)

Query: 448 VEEEGDVDSDEEEEEDEESSSEGLEAEDWAQG-VVEAGGSFGAYGAQEEAQCPTLHFLEG 506
           ++ + + + D+EE+ED+E   E  E ED   G   E GG      +++E+        E 
Sbjct: 671 LQSKSESEEDDEEDEDDEDEDE--EEEDDENGDSSEDGGDSSESSSEDES--------ED 720

Query: 507 GEDSDSDSEEEDDEEEDDEDEDDDDD 532
           G++++ D E+EDD+E+DDEDED++ +
Sbjct: 721 GDENEEDDEDEDDDEDDDEDEDNESE 746



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 18/29 (62%), Positives = 27/29 (93%), Gaps = 1/29 (3%)

Query: 510 SDSDSEEEDDEEEDDEDED-DDDDEEDGD 537
           S S+SEE+D+E+EDDEDED +++D+E+GD
Sbjct: 673 SKSESEEDDEEDEDDEDEDEEEEDDENGD 701



 Score = 40.0 bits (92), Expect = 0.006
 Identities = 15/48 (31%), Positives = 29/48 (60%)

Query: 491 GAQEEAQCPTLHFLEGGEDSDSDSEEEDDEEEDDEDEDDDDDEEDGDE 538
           G   ++   TL      E+ D + E+++DE+E++ED+++ D  EDG +
Sbjct: 661 GPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGD 708



 Score = 37.7 bits (86), Expect = 0.030
 Identities = 14/51 (27%), Positives = 29/51 (56%)

Query: 403 SEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGD 453
           SE E E+ +E EE++E+ + +E+++E E+ E EG         +  + + +
Sbjct: 714 SEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 764



 Score = 36.6 bits (83), Expect = 0.068
 Identities = 19/56 (33%), Positives = 31/56 (55%), Gaps = 4/56 (7%)

Query: 403 SEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGD-VDSD 457
           SE   E+E E+ +E EE + +E+++E ++E+E   + E  G        GD  DSD
Sbjct: 710 SESSSEDESEDGDENEEDDEDEDDDEDDDEDE---DNESEGSSSSSSSSGDSSDSD 762



 Score = 32.0 bits (71), Expect = 1.7
 Identities = 14/42 (33%), Positives = 26/42 (61%), Gaps = 2/42 (4%)

Query: 390 GGGPNATITTSLKSEGEEEEE--EEEEEEEEEGEGEEEEEEG 429
           GG  + + +     +G+E EE  E+E+++E++ E E+ E EG
Sbjct: 706 GGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEG 747



 Score = 30.0 bits (66), Expect = 6.3
 Identities = 11/35 (31%), Positives = 21/35 (60%)

Query: 504 LEGGEDSDSDSEEEDDEEEDDEDEDDDDDEEDGDE 538
           L G     S +  +   E +++DE+D+DDE++ +E
Sbjct: 659 LRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEE 693


>gi|42476169 Paf1, RNA polymerase II associated factor, homolog
           [Homo sapiens]
          Length = 531

 Score = 72.4 bits (176), Expect = 1e-12
 Identities = 46/132 (34%), Positives = 59/132 (44%), Gaps = 28/132 (21%)

Query: 406 EEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEEEEDEE 465
           EEEEEE E EE+E G  +EE+E+G   E+EG E E  G E E EE      D +E  D+ 
Sbjct: 378 EEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHSGSESEREE-----GDRDEASDKS 432

Query: 466 SSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHFLEGGEDSDSDSEEEDDEEEDDE 525
            S E   +ED A+   +    FG                       SD++ EDD + DDE
Sbjct: 433 GSGEDESSEDEARAARDKEEIFG-----------------------SDADSEDDADSDDE 469

Query: 526 DEDDDDDEEDGD 537
           D        D D
Sbjct: 470 DRGQAQGGSDND 481



 Score = 46.2 bits (108), Expect = 9e-05
 Identities = 37/150 (24%), Positives = 65/150 (43%), Gaps = 10/150 (6%)

Query: 385 REAGFGGGPNATITTSLKSEGEEEEE---EEEEEEEEEGEGEEEEEEGEEEEEEGGEGEE 441
           +EAG G        +S + EG E+E    E E EE +  E  ++   GE+E  E    +E
Sbjct: 389 KEAG-GSDEEQEKGSSSEKEGSEDEHSGSESEREEGDRDEASDKSGSGEDESSE----DE 443

Query: 442 LGEEEEVEEEGDVDSDEEEEEDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTL 501
                + EE    D+D E++ D +    G +A+  +    ++G + G   ++  ++  + 
Sbjct: 444 ARAARDKEEIFGSDADSEDDADSDDEDRG-QAQGGSDNDSDSGSNGGGQRSRSHSRSAS- 501

Query: 502 HFLEGGEDSDSDSEEEDDEEEDDEDEDDDD 531
            F  G E S  +   E    +  E + D D
Sbjct: 502 PFPSGSEHSAQEDGSEAAASDSSEADSDSD 531



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 43/154 (27%), Positives = 57/154 (37%), Gaps = 49/154 (31%)

Query: 386 EAGFGGGPNATITTSLKSEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEE 445
           +AG   G NA +          +  E+E E +E  + + E  E EEEEEE         E
Sbjct: 338 KAGVQSGTNALLVVK-----HRDMNEKELEAQEARKAQLENHEPEEEEEE---------E 383

Query: 446 EEVEEEGDVDSDEEEEEDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHFLE 505
            E EE+    SDEE+E+   S  EG E                                 
Sbjct: 384 METEEKEAGGSDEEQEKGSSSEKEGSE--------------------------------- 410

Query: 506 GGEDSDSDSE-EEDDEEEDDEDEDDDDDEEDGDE 538
             E S S+SE EE D +E  +     +DE   DE
Sbjct: 411 -DEHSGSESEREEGDRDEASDKSGSGEDESSEDE 443


>gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]
          Length = 770

 Score = 71.6 bits (174), Expect = 2e-12
 Identities = 38/77 (49%), Positives = 48/77 (62%), Gaps = 4/77 (5%)

Query: 394 NATITTSLKSEGEEEEEEEEEEEEEEG----EGEEEEEEGEEEEEEGGEGEELGEEEEVE 449
           +A  +++    G EEEEEEEEEEEEEG    E EEEEEE EEEEEE G   E   E+  E
Sbjct: 266 SAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAE 325

Query: 450 EEGDVDSDEEEEEDEES 466
           E  + +  E+EE + E+
Sbjct: 326 EVSEEEMSEDEERENEN 342



 Score = 68.9 bits (167), Expect = 1e-11
 Identities = 50/139 (35%), Positives = 64/139 (46%), Gaps = 14/139 (10%)

Query: 403 SEGEEEEEEEEEEEEEEGEG-EEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEEE 461
           S+ E +    E    E G G EEEEEE EEEEEEG   EE  EEEE EEE + ++    E
Sbjct: 258 SDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSE 317

Query: 462 EDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHFLEGGEDSDSDSEEEDDEE 521
           E  E S+E +  E+ ++              + E +   L   E   D DS  E E+ EE
Sbjct: 318 EASEQSAEEVSEEEMSE------------DEERENENHLLVVPESRFDRDS-GESEEAEE 364

Query: 522 EDDEDEDDDDDEEDGDEVP 540
           E  E         +GD VP
Sbjct: 365 EVGEGTPQSSALTEGDYVP 383



 Score = 67.4 bits (163), Expect = 4e-11
 Identities = 40/99 (40%), Positives = 53/99 (53%), Gaps = 2/99 (2%)

Query: 373 QAVEPSDIAACFREAGFGGGPNATITTSLKSEGEEEEEEEEEEEEEEGEGEEEEEEGEEE 432
           + +E  D+ +  ++        ++  +S    G   EEEEEEEEEEE EG   EE  EEE
Sbjct: 243 EKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEE 302

Query: 433 EEEGGEGEELG--EEEEVEEEGDVDSDEEEEEDEESSSE 469
           EEE  E EE G   EE  E+  +  S+EE  EDEE  +E
Sbjct: 303 EEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENE 341



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 38/164 (23%), Positives = 67/164 (40%), Gaps = 24/164 (14%)

Query: 407 EEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEE------------------EEV 448
           E+++E+ E++E E   EE  +E E   E       + E+                   E 
Sbjct: 171 EQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRER 230

Query: 449 EEEGD----VDSDEEEEEDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHFL 504
            E GD    V  ++ EE D  S  + +   +      E+  +    G++EE +       
Sbjct: 231 FELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEE 290

Query: 505 EGG--EDSDSDSEEEDDEEEDDEDEDDDDDEEDGDEVPVPSFGE 546
           EG   E+S+ + EEE++EEE+     ++  E+  +EV      E
Sbjct: 291 EGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSE 334



 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 33/81 (40%), Positives = 39/81 (48%), Gaps = 18/81 (22%)

Query: 395 ATITTSLKSEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEG-- 452
           +T   S + E EEEEEEEE        G   EE  E+  EE  E EE+ E+EE E E   
Sbjct: 293 STSEESEEEEEEEEEEEEE-------TGSNSEEASEQSAEEVSE-EEMSEDEERENENHL 344

Query: 453 --------DVDSDEEEEEDEE 465
                   D DS E EE +EE
Sbjct: 345 LVVPESRFDRDSGESEEAEEE 365



 Score = 34.7 bits (78), Expect = 0.26
 Identities = 37/180 (20%), Positives = 65/180 (36%), Gaps = 47/180 (26%)

Query: 406 EEEEEEEE--------------------------EEEEEEGEGEEEEEEGEEEEEEGGEG 439
           +   EE++                          E+ E + E E +  E ++E+ E  E 
Sbjct: 123 KRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKER 182

Query: 440 EELGEEEEVEEEGDVDSDEEEEEDEESSSEGLEAEDWAQGV-------VEAGGSFGAYGA 492
           E   EE   E E   +         E  S+ ++A  W++          E G        
Sbjct: 183 ERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKE 242

Query: 493 QEEAQCPTLHFLEGGEDSD--------------SDSEEEDDEEEDDEDEDDDDDEEDGDE 538
           ++  +   L  L+   DS+              S SEEE++EEE++E+E    +E + +E
Sbjct: 243 EKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEE 302


>gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]
          Length = 780

 Score = 71.6 bits (174), Expect = 2e-12
 Identities = 38/77 (49%), Positives = 48/77 (62%), Gaps = 4/77 (5%)

Query: 394 NATITTSLKSEGEEEEEEEEEEEEEEG----EGEEEEEEGEEEEEEGGEGEELGEEEEVE 449
           +A  +++    G EEEEEEEEEEEEEG    E EEEEEE EEEEEE G   E   E+  E
Sbjct: 276 SAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAE 335

Query: 450 EEGDVDSDEEEEEDEES 466
           E  + +  E+EE + E+
Sbjct: 336 EVSEEEMSEDEERENEN 352



 Score = 68.9 bits (167), Expect = 1e-11
 Identities = 50/139 (35%), Positives = 64/139 (46%), Gaps = 14/139 (10%)

Query: 403 SEGEEEEEEEEEEEEEEGEG-EEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEEE 461
           S+ E +    E    E G G EEEEEE EEEEEEG   EE  EEEE EEE + ++    E
Sbjct: 268 SDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSE 327

Query: 462 EDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHFLEGGEDSDSDSEEEDDEE 521
           E  E S+E +  E+ ++              + E +   L   E   D DS  E E+ EE
Sbjct: 328 EASEQSAEEVSEEEMSE------------DEERENENHLLVVPESRFDRDS-GESEEAEE 374

Query: 522 EDDEDEDDDDDEEDGDEVP 540
           E  E         +GD VP
Sbjct: 375 EVGEGTPQSSALTEGDYVP 393



 Score = 67.4 bits (163), Expect = 4e-11
 Identities = 40/99 (40%), Positives = 53/99 (53%), Gaps = 2/99 (2%)

Query: 373 QAVEPSDIAACFREAGFGGGPNATITTSLKSEGEEEEEEEEEEEEEEGEGEEEEEEGEEE 432
           + +E  D+ +  ++        ++  +S    G   EEEEEEEEEEE EG   EE  EEE
Sbjct: 253 EKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEE 312

Query: 433 EEEGGEGEELG--EEEEVEEEGDVDSDEEEEEDEESSSE 469
           EEE  E EE G   EE  E+  +  S+EE  EDEE  +E
Sbjct: 313 EEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENE 351



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 38/164 (23%), Positives = 67/164 (40%), Gaps = 24/164 (14%)

Query: 407 EEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEE------------------EEV 448
           E+++E+ E++E E   EE  +E E   E       + E+                   E 
Sbjct: 181 EQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRER 240

Query: 449 EEEGD----VDSDEEEEEDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHFL 504
            E GD    V  ++ EE D  S  + +   +      E+  +    G++EE +       
Sbjct: 241 FELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEE 300

Query: 505 EGG--EDSDSDSEEEDDEEEDDEDEDDDDDEEDGDEVPVPSFGE 546
           EG   E+S+ + EEE++EEE+     ++  E+  +EV      E
Sbjct: 301 EGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSE 344



 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 33/81 (40%), Positives = 39/81 (48%), Gaps = 18/81 (22%)

Query: 395 ATITTSLKSEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEG-- 452
           +T   S + E EEEEEEEE        G   EE  E+  EE  E EE+ E+EE E E   
Sbjct: 303 STSEESEEEEEEEEEEEEE-------TGSNSEEASEQSAEEVSE-EEMSEDEERENENHL 354

Query: 453 --------DVDSDEEEEEDEE 465
                   D DS E EE +EE
Sbjct: 355 LVVPESRFDRDSGESEEAEEE 375



 Score = 38.1 bits (87), Expect = 0.023
 Identities = 40/195 (20%), Positives = 70/195 (35%), Gaps = 47/195 (24%)

Query: 391 GGPNATITTSLKSEGEEEEEEEE--------------------------EEEEEEGEGEE 424
           GG +A +        +   EE++                          E+ E + E E 
Sbjct: 118 GGKHARVKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERER 177

Query: 425 EEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEEEEDEESSSEGLEAEDWAQGV---- 480
           +  E ++E+ E  E E   EE   E E   +         E  S+ ++A  W++      
Sbjct: 178 KMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPP 237

Query: 481 ---VEAGGSFGAYGAQEEAQCPTLHFLEGGEDSD--------------SDSEEEDDEEED 523
               E G        ++  +   L  L+   DS+              S SEEE++EEE+
Sbjct: 238 RERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEE 297

Query: 524 DEDEDDDDDEEDGDE 538
           +E+E    +E + +E
Sbjct: 298 EEEEGSTSEESEEEE 312


>gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           9 [Homo sapiens]
          Length = 771

 Score = 71.6 bits (174), Expect = 2e-12
 Identities = 38/77 (49%), Positives = 48/77 (62%), Gaps = 4/77 (5%)

Query: 394 NATITTSLKSEGEEEEEEEEEEEEEEG----EGEEEEEEGEEEEEEGGEGEELGEEEEVE 449
           +A  +++    G EEEEEEEEEEEEEG    E EEEEEE EEEEEE G   E   E+  E
Sbjct: 267 SAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAE 326

Query: 450 EEGDVDSDEEEEEDEES 466
           E  + +  E+EE + E+
Sbjct: 327 EVSEEEMSEDEERENEN 343



 Score = 68.9 bits (167), Expect = 1e-11
 Identities = 50/139 (35%), Positives = 64/139 (46%), Gaps = 14/139 (10%)

Query: 403 SEGEEEEEEEEEEEEEEGEG-EEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEEE 461
           S+ E +    E    E G G EEEEEE EEEEEEG   EE  EEEE EEE + ++    E
Sbjct: 259 SDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSE 318

Query: 462 EDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHFLEGGEDSDSDSEEEDDEE 521
           E  E S+E +  E+ ++              + E +   L   E   D DS  E E+ EE
Sbjct: 319 EASEQSAEEVSEEEMSE------------DEERENENHLLVVPESRFDRDS-GESEEAEE 365

Query: 522 EDDEDEDDDDDEEDGDEVP 540
           E  E         +GD VP
Sbjct: 366 EVGEGTPQSSALTEGDYVP 384



 Score = 67.4 bits (163), Expect = 4e-11
 Identities = 40/99 (40%), Positives = 53/99 (53%), Gaps = 2/99 (2%)

Query: 373 QAVEPSDIAACFREAGFGGGPNATITTSLKSEGEEEEEEEEEEEEEEGEGEEEEEEGEEE 432
           + +E  D+ +  ++        ++  +S    G   EEEEEEEEEEE EG   EE  EEE
Sbjct: 244 EKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEE 303

Query: 433 EEEGGEGEELG--EEEEVEEEGDVDSDEEEEEDEESSSE 469
           EEE  E EE G   EE  E+  +  S+EE  EDEE  +E
Sbjct: 304 EEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENE 342



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 38/164 (23%), Positives = 67/164 (40%), Gaps = 24/164 (14%)

Query: 407 EEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEE------------------EEV 448
           E+++E+ E++E E   EE  +E E   E       + E+                   E 
Sbjct: 172 EQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRER 231

Query: 449 EEEGD----VDSDEEEEEDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHFL 504
            E GD    V  ++ EE D  S  + +   +      E+  +    G++EE +       
Sbjct: 232 FELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEE 291

Query: 505 EGG--EDSDSDSEEEDDEEEDDEDEDDDDDEEDGDEVPVPSFGE 546
           EG   E+S+ + EEE++EEE+     ++  E+  +EV      E
Sbjct: 292 EGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSE 335



 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 33/81 (40%), Positives = 39/81 (48%), Gaps = 18/81 (22%)

Query: 395 ATITTSLKSEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEG-- 452
           +T   S + E EEEEEEEE        G   EE  E+  EE  E EE+ E+EE E E   
Sbjct: 294 STSEESEEEEEEEEEEEEE-------TGSNSEEASEQSAEEVSE-EEMSEDEERENENHL 345

Query: 453 --------DVDSDEEEEEDEE 465
                   D DS E EE +EE
Sbjct: 346 LVVPESRFDRDSGESEEAEEE 366



 Score = 34.7 bits (78), Expect = 0.26
 Identities = 37/180 (20%), Positives = 65/180 (36%), Gaps = 47/180 (26%)

Query: 406 EEEEEEEE--------------------------EEEEEEGEGEEEEEEGEEEEEEGGEG 439
           +   EE++                          E+ E + E E +  E ++E+ E  E 
Sbjct: 124 KRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKER 183

Query: 440 EELGEEEEVEEEGDVDSDEEEEEDEESSSEGLEAEDWAQGV-------VEAGGSFGAYGA 492
           E   EE   E E   +         E  S+ ++A  W++          E G        
Sbjct: 184 ERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKE 243

Query: 493 QEEAQCPTLHFLEGGEDSD--------------SDSEEEDDEEEDDEDEDDDDDEEDGDE 538
           ++  +   L  L+   DS+              S SEEE++EEE++E+E    +E + +E
Sbjct: 244 EKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEE 303



 Score = 30.4 bits (67), Expect = 4.9
 Identities = 31/99 (31%), Positives = 38/99 (38%), Gaps = 6/99 (6%)

Query: 403 SEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEE---EGDVDSDEE 459
           SE   EE  EEE  E+E   E E E       E     + GE EE EE   EG   S   
Sbjct: 321 SEQSAEEVSEEEMSEDE---ERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSAL 377

Query: 460 EEEDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQC 498
            E D    S  L   +  Q + +   +     + EE QC
Sbjct: 378 TEGDYVPDSPALSPIELKQELPKYLPALQGCRSVEEFQC 416


>gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           8 [Homo sapiens]
          Length = 780

 Score = 71.6 bits (174), Expect = 2e-12
 Identities = 38/77 (49%), Positives = 48/77 (62%), Gaps = 4/77 (5%)

Query: 394 NATITTSLKSEGEEEEEEEEEEEEEEG----EGEEEEEEGEEEEEEGGEGEELGEEEEVE 449
           +A  +++    G EEEEEEEEEEEEEG    E EEEEEE EEEEEE G   E   E+  E
Sbjct: 276 SAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAE 335

Query: 450 EEGDVDSDEEEEEDEES 466
           E  + +  E+EE + E+
Sbjct: 336 EVSEEEMSEDEERENEN 352



 Score = 68.9 bits (167), Expect = 1e-11
 Identities = 50/139 (35%), Positives = 64/139 (46%), Gaps = 14/139 (10%)

Query: 403 SEGEEEEEEEEEEEEEEGEG-EEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEEE 461
           S+ E +    E    E G G EEEEEE EEEEEEG   EE  EEEE EEE + ++    E
Sbjct: 268 SDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSE 327

Query: 462 EDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHFLEGGEDSDSDSEEEDDEE 521
           E  E S+E +  E+ ++              + E +   L   E   D DS  E E+ EE
Sbjct: 328 EASEQSAEEVSEEEMSE------------DEERENENHLLVVPESRFDRDS-GESEEAEE 374

Query: 522 EDDEDEDDDDDEEDGDEVP 540
           E  E         +GD VP
Sbjct: 375 EVGEGTPQSSALTEGDYVP 393



 Score = 67.4 bits (163), Expect = 4e-11
 Identities = 40/99 (40%), Positives = 53/99 (53%), Gaps = 2/99 (2%)

Query: 373 QAVEPSDIAACFREAGFGGGPNATITTSLKSEGEEEEEEEEEEEEEEGEGEEEEEEGEEE 432
           + +E  D+ +  ++        ++  +S    G   EEEEEEEEEEE EG   EE  EEE
Sbjct: 253 EKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEE 312

Query: 433 EEEGGEGEELG--EEEEVEEEGDVDSDEEEEEDEESSSE 469
           EEE  E EE G   EE  E+  +  S+EE  EDEE  +E
Sbjct: 313 EEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENE 351



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 38/164 (23%), Positives = 67/164 (40%), Gaps = 24/164 (14%)

Query: 407 EEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEE------------------EEV 448
           E+++E+ E++E E   EE  +E E   E       + E+                   E 
Sbjct: 181 EQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRER 240

Query: 449 EEEGD----VDSDEEEEEDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHFL 504
            E GD    V  ++ EE D  S  + +   +      E+  +    G++EE +       
Sbjct: 241 FELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEE 300

Query: 505 EGG--EDSDSDSEEEDDEEEDDEDEDDDDDEEDGDEVPVPSFGE 546
           EG   E+S+ + EEE++EEE+     ++  E+  +EV      E
Sbjct: 301 EGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSE 344



 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 33/81 (40%), Positives = 39/81 (48%), Gaps = 18/81 (22%)

Query: 395 ATITTSLKSEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEG-- 452
           +T   S + E EEEEEEEE        G   EE  E+  EE  E EE+ E+EE E E   
Sbjct: 303 STSEESEEEEEEEEEEEEE-------TGSNSEEASEQSAEEVSE-EEMSEDEERENENHL 354

Query: 453 --------DVDSDEEEEEDEE 465
                   D DS E EE +EE
Sbjct: 355 LVVPESRFDRDSGESEEAEEE 375



 Score = 30.4 bits (67), Expect = 4.9
 Identities = 31/99 (31%), Positives = 38/99 (38%), Gaps = 6/99 (6%)

Query: 403 SEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEE---EGDVDSDEE 459
           SE   EE  EEE  E+E   E E E       E     + GE EE EE   EG   S   
Sbjct: 330 SEQSAEEVSEEEMSEDE---ERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSAL 386

Query: 460 EEEDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQC 498
            E D    S  L   +  Q + +   +     + EE QC
Sbjct: 387 TEGDYVPDSPALSPIELKQELPKYLPALQGCRSVEEFQC 425


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.310    0.130    0.370 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,747,228
Number of Sequences: 37866
Number of extensions: 1585896
Number of successful extensions: 107807
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1393
Number of HSP's successfully gapped in prelim test: 581
Number of HSP's that attempted gapping in prelim test: 19781
Number of HSP's gapped (non-prelim): 31779
length of query: 599
length of database: 18,247,518
effective HSP length: 108
effective length of query: 491
effective length of database: 14,157,990
effective search space: 6951573090
effective search space used: 6951573090
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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