Search of human proteins with 21536415

Search of human proteins with 21536415

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|21536415 bridging integrator 1 isoform 9 [Homo sapiens]
         (439 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|21536415 bridging integrator 1 isoform 9 [Homo sapiens]            884   0.0  
gi|4757748 bridging integrator 1 isoform 8 [Homo sapiens]             874   0.0  
gi|21536413 bridging integrator 1 isoform 7 [Homo sapiens]            866   0.0  
gi|21536411 bridging integrator 1 isoform 6 [Homo sapiens]            863   0.0  
gi|21536407 bridging integrator 1 isoform 4 [Homo sapiens]            853   0.0  
gi|21536404 bridging integrator 1 isoform 3 [Homo sapiens]            850   0.0  
gi|21536417 bridging integrator 1 isoform 10 [Homo sapiens]           812   0.0  
gi|21536409 bridging integrator 1 isoform 5 [Homo sapiens]            806   0.0  
gi|21536402 bridging integrator 1 isoform 2 [Homo sapiens]            779   0.0  
gi|21536400 bridging integrator 1 isoform 1 [Homo sapiens]            595   e-170
gi|21536423 amphiphysin isoform 2 [Homo sapiens]                      367   e-102
gi|4502081 amphiphysin isoform 1 [Homo sapiens]                       367   e-102
gi|49472835 bridging integrator 2 [Homo sapiens]                      311   1e-84
gi|8923904 bridging integrator 3 [Homo sapiens]                        57   3e-08
gi|39930351 dynamin binding protein [Homo sapiens]                     49   7e-06
gi|49640014 ubiquitin associated and SH3 domain containing, A sh...    46   6e-05
gi|9507221 ubiquitin associated and SH3 domain containing, A lon...    46   6e-05
gi|4826964 UV excision repair protein RAD23 homolog A [Homo sapi...    45   1e-04
gi|115527120 nebulin [Homo sapiens]                                    44   2e-04
gi|110832843 TBP-associated factor 4 [Homo sapiens]                    44   3e-04
gi|7662162 ALEX2 protein [Homo sapiens]                                43   5e-04
gi|29540562 ALEX2 protein [Homo sapiens]                               43   5e-04
gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo sap...    42   0.001
gi|24308229 protein kinase C and casein kinase substrate in neur...    42   0.001
gi|219842343 glutamate receptor, metabotropic 5 isoform a precur...    41   0.002
gi|4504143 glutamate receptor, metabotropic 5 isoform b precurso...    41   0.002
gi|189181724 proteoglycan 4 isoform D [Homo sapiens]                   41   0.002
gi|189181722 proteoglycan 4 isoform C [Homo sapiens]                   41   0.002
gi|189181720 proteoglycan 4 isoform B [Homo sapiens]                   41   0.002
gi|67190163 proteoglycan 4 isoform A [Homo sapiens]                    41   0.002

>gi|21536415 bridging integrator 1 isoform 9 [Homo sapiens]
          Length = 439

 Score =  884 bits (2284), Expect = 0.0
 Identities = 439/439 (100%), Positives = 439/439 (100%)

Query: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60
           MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR
Sbjct: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60

Query: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120
           LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD
Sbjct: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120

Query: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK 180
           QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK
Sbjct: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK 180

Query: 181 AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE 240
           AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE
Sbjct: 181 AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE 240

Query: 241 KQHGSNTFTVKAQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKS 300
           KQHGSNTFTVKAQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKS
Sbjct: 241 KQHGSNTFTVKAQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKS 300

Query: 301 PSQPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGR 360
           PSQPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGR
Sbjct: 301 PSQPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGR 360

Query: 361 LDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQH 420
           LDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQH
Sbjct: 361 LDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQH 420

Query: 421 KELEKCRGVFPENFTERVP 439
           KELEKCRGVFPENFTERVP
Sbjct: 421 KELEKCRGVFPENFTERVP 439


>gi|4757748 bridging integrator 1 isoform 8 [Homo sapiens]
          Length = 454

 Score =  874 bits (2258), Expect = 0.0
 Identities = 439/454 (96%), Positives = 439/454 (96%), Gaps = 15/454 (3%)

Query: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60
           MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR
Sbjct: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60

Query: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120
           LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD
Sbjct: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120

Query: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK 180
           QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK
Sbjct: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK 180

Query: 181 AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE 240
           AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE
Sbjct: 181 AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE 240

Query: 241 KQHGSNTFTVKAQP---------------SDNAPAKGNKSPSPPDGSPAATPEIRVNHEP 285
           KQHGSNTFTVKAQP               SDNAPAKGNKSPSPPDGSPAATPEIRVNHEP
Sbjct: 241 KQHGSNTFTVKAQPRKKSKLFSRLRRKKNSDNAPAKGNKSPSPPDGSPAATPEIRVNHEP 300

Query: 286 EPAGGATPGATLPKSPSQPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFP 345
           EPAGGATPGATLPKSPSQPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFP
Sbjct: 301 EPAGGATPGATLPKSPSQPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFP 360

Query: 346 ATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQD 405
           ATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQD
Sbjct: 361 ATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQD 420

Query: 406 EGWLMGVKESDWNQHKELEKCRGVFPENFTERVP 439
           EGWLMGVKESDWNQHKELEKCRGVFPENFTERVP
Sbjct: 421 EGWLMGVKESDWNQHKELEKCRGVFPENFTERVP 454


>gi|21536413 bridging integrator 1 isoform 7 [Homo sapiens]
          Length = 475

 Score =  866 bits (2237), Expect = 0.0
 Identities = 439/475 (92%), Positives = 439/475 (92%), Gaps = 36/475 (7%)

Query: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60
           MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR
Sbjct: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60

Query: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120
           LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD
Sbjct: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120

Query: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK 180
           QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK
Sbjct: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK 180

Query: 181 AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE 240
           AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE
Sbjct: 181 AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE 240

Query: 241 KQHGSNTFTVKAQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKS 300
           KQHGSNTFTVKAQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKS
Sbjct: 241 KQHGSNTFTVKAQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKS 300

Query: 301 PS------------------------------------QPAEASEVAGGTQPAAGAQEPG 324
           PS                                    QPAEASEVAGGTQPAAGAQEPG
Sbjct: 301 PSQPTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPG 360

Query: 325 ETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDE 384
           ETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDE
Sbjct: 361 ETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDE 420

Query: 385 LQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERVP 439
           LQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERVP
Sbjct: 421 LQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERVP 475


>gi|21536411 bridging integrator 1 isoform 6 [Homo sapiens]
          Length = 482

 Score =  863 bits (2230), Expect = 0.0
 Identities = 439/482 (91%), Positives = 439/482 (91%), Gaps = 43/482 (8%)

Query: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60
           MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR
Sbjct: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60

Query: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120
           LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD
Sbjct: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120

Query: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK 180
           QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK
Sbjct: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK 180

Query: 181 AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE 240
           AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE
Sbjct: 181 AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE 240

Query: 241 KQHGSNTFTVKAQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKS 300
           KQHGSNTFTVKAQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKS
Sbjct: 241 KQHGSNTFTVKAQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKS 300

Query: 301 -------------------------------------------PSQPAEASEVAGGTQPA 317
                                                      PSQPAEASEVAGGTQPA
Sbjct: 301 PSQLRKGPPVPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPSQPAEASEVAGGTQPA 360

Query: 318 AGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDY 377
           AGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDY
Sbjct: 361 AGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDY 420

Query: 378 TATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTER 437
           TATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTER
Sbjct: 421 TATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTER 480

Query: 438 VP 439
           VP
Sbjct: 481 VP 482


>gi|21536407 bridging integrator 1 isoform 4 [Homo sapiens]
          Length = 497

 Score =  853 bits (2204), Expect = 0.0
 Identities = 439/497 (88%), Positives = 439/497 (88%), Gaps = 58/497 (11%)

Query: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60
           MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR
Sbjct: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60

Query: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120
           LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD
Sbjct: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120

Query: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK 180
           QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK
Sbjct: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK 180

Query: 181 AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE 240
           AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE
Sbjct: 181 AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE 240

Query: 241 KQHGSNTFTVKAQP---------------SDNAPAKGNKSPSPPDGSPAATPEIRVNHEP 285
           KQHGSNTFTVKAQP               SDNAPAKGNKSPSPPDGSPAATPEIRVNHEP
Sbjct: 241 KQHGSNTFTVKAQPRKKSKLFSRLRRKKNSDNAPAKGNKSPSPPDGSPAATPEIRVNHEP 300

Query: 286 EPAGGATPGATLPKS-------------------------------------------PS 302
           EPAGGATPGATLPKS                                           PS
Sbjct: 301 EPAGGATPGATLPKSPSQLRKGPPVPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPS 360

Query: 303 QPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLD 362
           QPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLD
Sbjct: 361 QPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLD 420

Query: 363 LPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKE 422
           LPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKE
Sbjct: 421 LPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKE 480

Query: 423 LEKCRGVFPENFTERVP 439
           LEKCRGVFPENFTERVP
Sbjct: 481 LEKCRGVFPENFTERVP 497


>gi|21536404 bridging integrator 1 isoform 3 [Homo sapiens]
          Length = 506

 Score =  850 bits (2195), Expect = 0.0
 Identities = 439/506 (86%), Positives = 439/506 (86%), Gaps = 67/506 (13%)

Query: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60
           MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR
Sbjct: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60

Query: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120
           LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD
Sbjct: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120

Query: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAK------- 173
           QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAK       
Sbjct: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKPVSLLEK 180

Query: 174 ------------------------AEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN 209
                                   AEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN
Sbjct: 181 AAPQWCQGKLQAHLVAQTNLLRNQAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN 240

Query: 210 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP 269
           TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP
Sbjct: 241 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP 300

Query: 270 DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQP------------------------- 304
           DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQP                         
Sbjct: 301 DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQPTESPAGSLPSGEPSAAEGTFAVSWP 360

Query: 305 -----------AEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVE 353
                      AEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVE
Sbjct: 361 SQTAEPGPAQPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVE 420

Query: 354 GGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVK 413
           GGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVK
Sbjct: 421 GGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVK 480

Query: 414 ESDWNQHKELEKCRGVFPENFTERVP 439
           ESDWNQHKELEKCRGVFPENFTERVP
Sbjct: 481 ESDWNQHKELEKCRGVFPENFTERVP 506


>gi|21536417 bridging integrator 1 isoform 10 [Homo sapiens]
          Length = 409

 Score =  812 bits (2097), Expect = 0.0
 Identities = 409/439 (93%), Positives = 409/439 (93%), Gaps = 30/439 (6%)

Query: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60
           MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR
Sbjct: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60

Query: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120
           LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD
Sbjct: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120

Query: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK 180
           QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK
Sbjct: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK 180

Query: 181 AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE 240
           AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE
Sbjct: 181 AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE 240

Query: 241 KQHGSNTFTVKAQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKS 300
           KQHGSNTFTVKAQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKS
Sbjct: 241 KQHGSNTFTVKAQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKS 300

Query: 301 PSQPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGR 360
           PSQ                              SSLPAVVVETFPATVNGTVEGGSGAGR
Sbjct: 301 PSQ------------------------------SSLPAVVVETFPATVNGTVEGGSGAGR 330

Query: 361 LDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQH 420
           LDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQH
Sbjct: 331 LDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQH 390

Query: 421 KELEKCRGVFPENFTERVP 439
           KELEKCRGVFPENFTERVP
Sbjct: 391 KELEKCRGVFPENFTERVP 409


>gi|21536409 bridging integrator 1 isoform 5 [Homo sapiens]
          Length = 518

 Score =  806 bits (2082), Expect = 0.0
 Identities = 420/518 (81%), Positives = 427/518 (82%), Gaps = 79/518 (15%)

Query: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60
           MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR
Sbjct: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60

Query: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120
           LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD
Sbjct: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120

Query: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK 180
           QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK
Sbjct: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK 180

Query: 181 AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE 240
           AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE
Sbjct: 181 AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE 240

Query: 241 KQHGSNTFTVKAQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKS 300
           KQHGSNTFTVKAQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKS
Sbjct: 241 KQHGSNTFTVKAQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKS 300

Query: 301 PSQ----------------------------------------PAEASEVAGGTQPA--- 317
           PSQ                                        P++ +E   G+ P+   
Sbjct: 301 PSQLRKGPPVPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPSQPTESPAGSLPSGEP 360

Query: 318 ------------AGAQEPGETAASEA------------------------ASSSLPAVVV 341
                       +   EPG    +EA                        ASSSLPAVVV
Sbjct: 361 SAAEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVV 420

Query: 342 ETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNP 401
           ETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNP
Sbjct: 421 ETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNP 480

Query: 402 EEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERVP 439
           EEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERVP
Sbjct: 481 EEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERVP 518


>gi|21536402 bridging integrator 1 isoform 2 [Homo sapiens]
          Length = 550

 Score =  779 bits (2012), Expect = 0.0
 Identities = 419/550 (76%), Positives = 423/550 (76%), Gaps = 111/550 (20%)

Query: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60
           MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR
Sbjct: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60

Query: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120
           LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD
Sbjct: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120

Query: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAK------- 173
           QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAK       
Sbjct: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKPVSLLEK 180

Query: 174 ------------------------AEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN 209
                                   AEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN
Sbjct: 181 AAPQWCQGKLQAHLVAQTNLLRNQAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN 240

Query: 210 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP 269
           TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP
Sbjct: 241 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP 300

Query: 270 DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQ---PAEASEVAG-------------- 312
           DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQ   P   SE A               
Sbjct: 301 DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQFEAPGPFSEQASLLDLDFDPLPPVTS 360

Query: 313 ------------------GTQPAAGAQEPGETA------------------------ASE 330
                              T+  AG+   GE +                        ASE
Sbjct: 361 PVKAPTPSGQSIPWDLWEPTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEASE 420

Query: 331 AASSSLPA---------------------VVVETFPATVNGTVEGGSGAGRLDLPPGFMF 369
            A  + PA                     VVVETFPATVNGTVEGGSGAGRLDLPPGFMF
Sbjct: 421 VAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMF 480

Query: 370 KVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGV 429
           KVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGV
Sbjct: 481 KVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGV 540

Query: 430 FPENFTERVP 439
           FPENFTERVP
Sbjct: 541 FPENFTERVP 550


>gi|21536400 bridging integrator 1 isoform 1 [Homo sapiens]
          Length = 593

 Score =  595 bits (1533), Expect = e-170
 Identities = 310/382 (81%), Positives = 318/382 (83%), Gaps = 40/382 (10%)

Query: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60
           MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR
Sbjct: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60

Query: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120
           LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD
Sbjct: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120

Query: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAK------- 173
           QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAK       
Sbjct: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKPVSLLEK 180

Query: 174 ------------------------AEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN 209
                                   AEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN
Sbjct: 181 AAPQWCQGKLQAHLVAQTNLLRNQAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN 240

Query: 210 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP 269
           TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP
Sbjct: 241 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP 300

Query: 270 DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQPAEASEVAGGTQPAAGAQEPGETAAS 329
           DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQ  +   V            P  T + 
Sbjct: 301 DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPV---------PPPPKHTPSK 351

Query: 330 EAASSSLPAVVVETFPATVNGT 351
           E     + ++  +TF   ++ T
Sbjct: 352 EVKQEQILSLFEDTFVPEISVT 373



 Score =  288 bits (737), Expect = 7e-78
 Identities = 148/175 (84%), Positives = 152/175 (86%), Gaps = 7/175 (4%)

Query: 269 PDGSPAATPEIRVNHEPEPAGG----ATPGATLPKSPSQPAEASEVAGGTQPAAGAQEPG 324
           P  SPA +     + EP  A G    + P  T    P+QPAEASEVAGGTQPAAGAQEPG
Sbjct: 422 PTESPAGSLP---SGEPSAAEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPG 478

Query: 325 ETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDE 384
           ETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDE
Sbjct: 479 ETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDE 538

Query: 385 LQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERVP 439
           LQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERVP
Sbjct: 539 LQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERVP 593


>gi|21536423 amphiphysin isoform 2 [Homo sapiens]
          Length = 653

 Score =  367 bits (943), Expect = e-102
 Identities = 184/303 (60%), Positives = 226/303 (74%), Gaps = 4/303 (1%)

Query: 9   VTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTRLQKDLRTY 68
           +  G  A NVQK+L RAQEKVLQKLGKADETKDEQFE+ VQNF +Q  EGTRLQ++LR Y
Sbjct: 4   IKTGIFAKNVQKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGTRLQRELRGY 63

Query: 69  LASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVDQALLTMDT 128
           LA++K M EAS KL E L EVYEPDW GR++   + E  D+LW D+HQKLVD +LLT+DT
Sbjct: 64  LAAIKGMQEASMKLTESLHEVYEPDWYGREDVKMVGEKCDVLWEDFHQKLVDGSLLTLDT 123

Query: 129 YLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIKAQKVFEEM 188
           YLGQFPDIK+RIAKR RKLVDYDSARHH E+LQ++K+KDE++I+KAEEE  KAQKVFEE 
Sbjct: 124 YLGQFPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISKAEEEFQKAQKVFEEF 183

Query: 189 NVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTF 248
           NVDLQEELPSLW+ RVGFYVNTF++++ LE  FHKE++ L   L +V+  L  QH    F
Sbjct: 184 NVDLQEELPSLWSRRVGFYVNTFKNVSSLEAKFHKEIAVLCHKLYEVMTKLGDQHADKAF 243

Query: 249 TVKAQPSDNAPAKGNKSPSPP-DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQPAEA 307
           T++  PSD+ P +  K+PSPP + SP  +P    NH   P   A+P    P+SPSQ  + 
Sbjct: 244 TIQGAPSDSGPLRIAKTPSPPEEPSPLPSPTASPNHTLAP---ASPAPARPRSPSQTRKG 300

Query: 308 SEV 310
             V
Sbjct: 301 PPV 303



 Score =  114 bits (284), Expect = 2e-25
 Identities = 75/231 (32%), Positives = 109/231 (47%), Gaps = 26/231 (11%)

Query: 233 NDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEP-EPAGGA 291
           N ++ G +      T    A+ +    A+  K+ + P G   +  E ++  E  E A  A
Sbjct: 423 NLIIPGADADAAVGTLVSAAEGAPGEEAEAEKA-TVPAGEGVSLEEAKIGTETTEGAESA 481

Query: 292 TPGA-----------TLPKSPSQPAEASEVAGGTQPAAGAQ--EPGETAASEAASSSLPA 338
            P A            +P    +PA   E  G  +   GA+  E  E AA    +S  P 
Sbjct: 482 QPEAEELEATVPQEKVIPSVVIEPASNHEEEGENEITIGAEPKETTEDAAPPGPTSETPE 541

Query: 339 VVVETFPATVNGTVEGGSGAGRLD-----------LPPGFMFKVQAQHDYTATDTDELQL 387
           +  E  P             G  D           LPPGF++KV+  HD+ A ++DEL L
Sbjct: 542 LATEQKPIQDPQPTPSAPAMGAADQLASAREASQELPPGFLYKVETLHDFEAANSDELTL 601

Query: 388 KAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERV 438
           + GDVVLV+P  +  +QD GWL+GVKESDW Q+++L   +G+FPENFT R+
Sbjct: 602 QRGDVVLVVPSDSEADQDAGWLVGVKESDWLQYRDLATYKGLFPENFTRRL 652


>gi|4502081 amphiphysin isoform 1 [Homo sapiens]
          Length = 695

 Score =  367 bits (943), Expect = e-102
 Identities = 184/303 (60%), Positives = 226/303 (74%), Gaps = 4/303 (1%)

Query: 9   VTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTRLQKDLRTY 68
           +  G  A NVQK+L RAQEKVLQKLGKADETKDEQFE+ VQNF +Q  EGTRLQ++LR Y
Sbjct: 4   IKTGIFAKNVQKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGTRLQRELRGY 63

Query: 69  LASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVDQALLTMDT 128
           LA++K M EAS KL E L EVYEPDW GR++   + E  D+LW D+HQKLVD +LLT+DT
Sbjct: 64  LAAIKGMQEASMKLTESLHEVYEPDWYGREDVKMVGEKCDVLWEDFHQKLVDGSLLTLDT 123

Query: 129 YLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIKAQKVFEEM 188
           YLGQFPDIK+RIAKR RKLVDYDSARHH E+LQ++K+KDE++I+KAEEE  KAQKVFEE 
Sbjct: 124 YLGQFPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISKAEEEFQKAQKVFEEF 183

Query: 189 NVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTF 248
           NVDLQEELPSLW+ RVGFYVNTF++++ LE  FHKE++ L   L +V+  L  QH    F
Sbjct: 184 NVDLQEELPSLWSRRVGFYVNTFKNVSSLEAKFHKEIAVLCHKLYEVMTKLGDQHADKAF 243

Query: 249 TVKAQPSDNAPAKGNKSPSPP-DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQPAEA 307
           T++  PSD+ P +  K+PSPP + SP  +P    NH   P   A+P    P+SPSQ  + 
Sbjct: 244 TIQGAPSDSGPLRIAKTPSPPEEPSPLPSPTASPNHTLAP---ASPAPARPRSPSQTRKG 300

Query: 308 SEV 310
             V
Sbjct: 301 PPV 303



 Score =  113 bits (282), Expect = 4e-25
 Identities = 74/229 (32%), Positives = 108/229 (47%), Gaps = 26/229 (11%)

Query: 235 VLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEP-EPAGGATP 293
           ++ G +      T    A+ +    A+  K+ + P G   +  E ++  E  E A  A P
Sbjct: 467 IIPGADADAAVGTLVSAAEGAPGEEAEAEKA-TVPAGEGVSLEEAKIGTETTEGAESAQP 525

Query: 294 GA-----------TLPKSPSQPAEASEVAGGTQPAAGAQ--EPGETAASEAASSSLPAVV 340
            A            +P    +PA   E  G  +   GA+  E  E AA    +S  P + 
Sbjct: 526 EAEELEATVPQEKVIPSVVIEPASNHEEEGENEITIGAEPKETTEDAAPPGPTSETPELA 585

Query: 341 VETFPATVNGTVEGGSGAGRLD-----------LPPGFMFKVQAQHDYTATDTDELQLKA 389
            E  P             G  D           LPPGF++KV+  HD+ A ++DEL L+ 
Sbjct: 586 TEQKPIQDPQPTPSAPAMGAADQLASAREASQELPPGFLYKVETLHDFEAANSDELTLQR 645

Query: 390 GDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERV 438
           GDVVLV+P  +  +QD GWL+GVKESDW Q+++L   +G+FPENFT R+
Sbjct: 646 GDVVLVVPSDSEADQDAGWLVGVKESDWLQYRDLATYKGLFPENFTRRL 694


>gi|49472835 bridging integrator 2 [Homo sapiens]
          Length = 565

 Score =  311 bits (796), Expect = 1e-84
 Identities = 173/344 (50%), Positives = 221/344 (64%), Gaps = 11/344 (3%)

Query: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60
           MAE G  G  AG  A  VQKK +RAQEKVLQKLGKA ETKDE+FEQ   NF +Q  EG +
Sbjct: 1   MAE-GKAGGAAGLFAKQVQKKFSRAQEKVLQKLGKAVETKDERFEQSASNFYQQQAEGHK 59

Query: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120
           L KDL+ +L++VK MHE+SK+++E LQE+Y  +W G +E   I  NNDLLW DY +KL D
Sbjct: 60  LYKDLKNFLSAVKVMHESSKRVSETLQEIYSSEWDGHEELKAIVWNNDLLWEDYEEKLAD 119

Query: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK 180
           QA+ TM+ Y+ QF +IK RIAKRGRKLVDYDSARHH E++Q AKKKDEAK AKAEEE  K
Sbjct: 120 QAVRTMEIYVAQFSEIKERIAKRGRKLVDYDSARHHLEAVQNAKKKDEAKTAKAEEEFNK 179

Query: 181 AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE 240
           AQ VFE++N +L EELP L+NSR+G YV  FQ+I+ L + F++EMSKLN NL +V+  LE
Sbjct: 180 AQTVFEDLNQELLEELPILYNSRIGCYVTIFQNISNLRDVFYREMSKLNHNLYEVMSKLE 239

Query: 241 KQHGSNTFTVKAQPSDN------APAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPG 294
           KQH +  F VK   S +      +P     + S P  SP +   + +  E E        
Sbjct: 240 KQHSNKVFVVKGLSSSSRRSLVISPPVRTATVSSPLTSPTSPSTLSLKSESESVSAT--- 296

Query: 295 ATLPKSPSQPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPA 338
             L    +Q  + SE+    +     +E  E ++SE     LPA
Sbjct: 297 EDLAPDAAQGEDNSEIKELLEEEEIEKEGSEASSSE-EDEPLPA 339


>gi|8923904 bridging integrator 3 [Homo sapiens]
          Length = 253

 Score = 57.0 bits (136), Expect = 3e-08
 Identities = 55/195 (28%), Positives = 100/195 (51%), Gaps = 14/195 (7%)

Query: 53  KQLTEGTR-LQKDLRTYLASVKAMHEASKKLNECL--QEVYEPDWPGRDEANKI-AENND 108
           +QL E TR LQKD++    +  AM +++ K++  L    + E D   +D  N + A +  
Sbjct: 32  QQLEEQTRRLQKDMKKSTDADLAMSKSAVKISLDLLSNPLCEQD---QDLLNMVTALDTA 88

Query: 109 LLWMD-YHQKLVDQALLTMDTYLGQF----PDIKSRIAKRGRKLVDYDSARHHYESLQTA 163
           +  MD ++Q+ V+Q   T+   L +F    P +   + +R + L DY   +   E  +  
Sbjct: 89  MKRMDAFNQEKVNQIQKTVIEPLKKFGSVFPSLNMAVKRREQALQDYRRLQAKVEKYEEK 148

Query: 164 KKKDE--AKIAKAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENF 221
           +K     AK+ +A EEL   ++ FE  N  L EE+P  + SR+ ++  +F+S+   +  +
Sbjct: 149 EKTGPVLAKLHQAREELRPVREDFEAKNRQLLEEMPRFYGSRLDYFQPSFESLIRAQVVY 208

Query: 222 HKEMSKLNQNLNDVL 236
           + EM K+  +L+  L
Sbjct: 209 YSEMHKIFGDLSHQL 223


>gi|39930351 dynamin binding protein [Homo sapiens]
          Length = 1577

 Score = 49.3 bits (116), Expect = 7e-06
 Identities = 50/223 (22%), Positives = 90/223 (40%), Gaps = 18/223 (8%)

Query: 17   NVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTRLQKDLRTYLASVKA-- 74
            ++ KK  R    +    G A + KDE FE+  +NF  Q        +DL  YL  ++   
Sbjct: 996  SIIKKSNRVSSHLKHLTGFAPQIKDEVFEETEKNFRMQERLIKSFIRDLSLYLQHIRESA 1055

Query: 75   ---MHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVDQALLTMDTYLG 131
               +  A    + C++  +  D    +  ++    +D L+ ++ ++     +  ++  L 
Sbjct: 1056 CVKVVAAVSMWDVCMERGHR-DLEQFERVHRYI--SDQLFTNFKERTERLVISPLNQLLS 1112

Query: 132  QFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIKAQKVFEEMNVD 191
             F      + KR  KL+D+ +     E L         K  K  EEL  A+  +E +N  
Sbjct: 1113 MFTGPHKLVQKRFDKLLDFYNCTERAEKL---------KDKKTLEELQSARNNYEALNAQ 1163

Query: 192  LQEELPSLWNSRVGFYVNTFQSIAGLEENF-HKEMSKLNQNLN 233
            L +ELP       G + N     A    +F H+ + +L   L+
Sbjct: 1164 LLDELPKFHQYAQGLFTNCVHGYAEAHCDFVHQALEQLKPLLS 1206



 Score = 35.8 bits (81), Expect = 0.079
 Identities = 25/81 (30%), Positives = 35/81 (43%), Gaps = 15/81 (18%)

Query: 356 SGAGRLDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKES 415
           S +    +P   M + +A    +A   +EL  + GDV+ +I    P     GW  G    
Sbjct: 135 SQSALFQIPEYSMGQARALMGLSAQLDEELDFREGDVITIIGVPEP-----GWFEG---- 185

Query: 416 DWNQHKELEKCRGVFPENFTE 436
                 ELE  RG+FPE F E
Sbjct: 186 ------ELEGRRGIFPEGFVE 200



 Score = 31.2 bits (69), Expect = 1.9
 Identities = 22/68 (32%), Positives = 32/68 (47%), Gaps = 15/68 (22%)

Query: 371 VQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVF 430
           V+A  D+  + ++EL L  GD++ V+        DE WL+G KE             G F
Sbjct: 7   VRAIFDFCPSVSEELPLFVGDIIEVLAV-----VDEFWLLGKKED----------VTGQF 51

Query: 431 PENFTERV 438
           P +F E V
Sbjct: 52  PSSFVEIV 59


>gi|49640014 ubiquitin associated and SH3 domain containing, A short
           form [Homo sapiens]
          Length = 623

 Score = 46.2 bits (108), Expect = 6e-05
 Identities = 24/67 (35%), Positives = 35/67 (52%), Gaps = 9/67 (13%)

Query: 371 VQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVF 430
           ++A   Y   + DEL L  GD + V P Q  +E  EGW++G+ +           CRG  
Sbjct: 243 LRALFQYKPQNVDELTLSPGDYIFVDPTQQ-DEASEGWVIGISQR--------TGCRGFL 293

Query: 431 PENFTER 437
           PEN+T+R
Sbjct: 294 PENYTDR 300


>gi|9507221 ubiquitin associated and SH3 domain containing, A long
           form [Homo sapiens]
          Length = 661

 Score = 46.2 bits (108), Expect = 6e-05
 Identities = 24/67 (35%), Positives = 35/67 (52%), Gaps = 9/67 (13%)

Query: 371 VQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVF 430
           ++A   Y   + DEL L  GD + V P Q  +E  EGW++G+ +           CRG  
Sbjct: 281 LRALFQYKPQNVDELTLSPGDYIFVDPTQQ-DEASEGWVIGISQR--------TGCRGFL 331

Query: 431 PENFTER 437
           PEN+T+R
Sbjct: 332 PENYTDR 338


>gi|4826964 UV excision repair protein RAD23 homolog A [Homo
           sapiens]
          Length = 363

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 27/80 (33%), Positives = 39/80 (48%), Gaps = 6/80 (7%)

Query: 262 GNKSPSPPDGSPAATPEIRVNHEPEPAGGAT---PGATLPKSPSQ---PAEASEVAGGTQ 315
           G  + +PP+ SP A PE   +  P P  G +   P A   KSPS+   P  + E   G+ 
Sbjct: 82  GQGTSAPPEASPTAAPESSTSFPPAPTSGMSHPPPAAREDKSPSEESAPTTSPESVSGSV 141

Query: 316 PAAGAQEPGETAASEAASSS 335
           P++G+    E AAS   + S
Sbjct: 142 PSSGSSGREEDAASTLVTGS 161


>gi|115527120 nebulin [Homo sapiens]
          Length = 6669

 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 38/157 (24%), Positives = 63/157 (40%), Gaps = 39/157 (24%)

Query: 299  KSPSQPAEASEVAGGTQPAAGAQEPGE--------------TAASEAASSSLP---AVVV 341
            +  S+ A A  ++GG + +  ++ P                TA   A ++ LP   +  V
Sbjct: 6535 REQSRSASALSISGGEEKSEHSEAPDHHLSTYSDGGVFAVSTAYKHAKTTELPQQRSSSV 6594

Query: 342  ETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNP 401
             T   TV+      S AG++          +A +DY A D DE+  K GD ++     N 
Sbjct: 6595 ATQQTTVSSIPSHPSTAGKI---------FRAMYDYMAADADEVSFKDGDAII-----NV 6640

Query: 402  EEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERV 438
            +  DEGW+ G  +             G+ P N+ E +
Sbjct: 6641 QAIDEGWMYGTVQRTGR--------TGMLPANYVEAI 6669


>gi|110832843 TBP-associated factor 4 [Homo sapiens]
          Length = 1085

 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 37/112 (33%), Positives = 46/112 (41%), Gaps = 9/112 (8%)

Query: 258 APAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQPAEASEV--AGGTQ 315
           A A G    +P +G+P A PE      P PAG A PG   P+ P  P+    +  AG   
Sbjct: 68  AGAAGAGPAAPAEGAPGAAPE------PPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAP 121

Query: 316 PAAGAQEPGE-TAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPG 366
           PAA  + P E +A S A   +  AV     PA        G  A      PG
Sbjct: 122 PAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPG 173



 Score = 40.0 bits (92), Expect = 0.004
 Identities = 36/117 (30%), Positives = 50/117 (42%), Gaps = 15/117 (12%)

Query: 252 AQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLP----KSPSQPAEA 307
           A P   A   G  + + P  +PAA     V+ +P P  GA   A  P    +SP +  +A
Sbjct: 296 AVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGP--GAAAAAPAPGVKAESPKRVVQA 353

Query: 308 SEVAGGTQPAAGAQEPGETAASEAASSSL------PAVVVETFPATVNGTVEGGSGA 358
           +  A  T  A+G   P  TAAS     ++      PA V    P T  G  +G +GA
Sbjct: 354 APPAAQTLAASG---PASTAASMVIGPTMQGALPSPAAVPPPAPGTPTGLPKGAAGA 407



 Score = 37.4 bits (85), Expect = 0.027
 Identities = 34/109 (31%), Positives = 43/109 (39%), Gaps = 18/109 (16%)

Query: 258 APAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQPAEASEVAGGTQPA 317
           APA  +   +P   +PAA P       P PA      ATL + P  PA     A    P 
Sbjct: 251 APAAPSPPAAPAPAAPAAAPP-----PPPPAP-----ATLARPPGHPAGPPTAAPAVPPP 300

Query: 318 AGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPG 366
           A AQ  G   A+ A + +         PA V+G  + G GA      PG
Sbjct: 301 AAAQNGGSAGAAPAPAPAAGG------PAGVSG--QPGPGAAAAAPAPG 341


>gi|7662162 ALEX2 protein [Homo sapiens]
          Length = 632

 Score = 43.1 bits (100), Expect = 5e-04
 Identities = 33/119 (27%), Positives = 45/119 (37%), Gaps = 4/119 (3%)

Query: 252 AQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPA----GGATPGATLPKSPSQPAEA 307
           A  S  AP  G         +PA     +V   P  A        PG  +P   + P E 
Sbjct: 134 AMASAIAPPPGVTEALGAAEAPAMAGAPKVAEAPREAETSRAAVPPGTVVPTEAAAPTEV 193

Query: 308 SEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPG 366
           +E  G   P   A+ PG  + +EAA + +PA        T      G SG+ R  + PG
Sbjct: 194 TEGPGVAAPTKVAEAPGVASPTEAAEAPVPATPTGAAAPTGAAESPGTSGSPRTAVVPG 252



 Score = 30.8 bits (68), Expect = 2.5
 Identities = 27/111 (24%), Positives = 40/111 (36%), Gaps = 10/111 (9%)

Query: 249 TVKAQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQPAEAS 308
           T  A P++     G  +P+    +P           P PA         P   + P  A+
Sbjct: 185 TEAAAPTEVTEGPGVAAPTKVAEAPGVASPTEAAEAPVPA--------TPTGAAAPTGAA 236

Query: 309 EVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAG 359
           E  G +     A  PG +AA +A   +    + +   AT  G V  G G G
Sbjct: 237 ESPGTSGSPRTAVVPGTSAAKKATPGAHTGAIPKATSAT--GAVPKGGGKG 285


>gi|29540562 ALEX2 protein [Homo sapiens]
          Length = 632

 Score = 43.1 bits (100), Expect = 5e-04
 Identities = 33/119 (27%), Positives = 45/119 (37%), Gaps = 4/119 (3%)

Query: 252 AQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPA----GGATPGATLPKSPSQPAEA 307
           A  S  AP  G         +PA     +V   P  A        PG  +P   + P E 
Sbjct: 134 AMASAIAPPPGVTEALGAAEAPAMAGAPKVAEAPREAETSRAAVPPGTVVPTEAAAPTEV 193

Query: 308 SEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPG 366
           +E  G   P   A+ PG  + +EAA + +PA        T      G SG+ R  + PG
Sbjct: 194 TEGPGVAAPTKVAEAPGVASPTEAAEAPVPATPTGAAAPTGAAESPGTSGSPRTAVVPG 252



 Score = 30.8 bits (68), Expect = 2.5
 Identities = 27/111 (24%), Positives = 40/111 (36%), Gaps = 10/111 (9%)

Query: 249 TVKAQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQPAEAS 308
           T  A P++     G  +P+    +P           P PA         P   + P  A+
Sbjct: 185 TEAAAPTEVTEGPGVAAPTKVAEAPGVASPTEAAEAPVPA--------TPTGAAAPTGAA 236

Query: 309 EVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAG 359
           E  G +     A  PG +AA +A   +    + +   AT  G V  G G G
Sbjct: 237 ESPGTSGSPRTAVVPGTSAAKKATPGAHTGAIPKATSAT--GAVPKGGGKG 285


>gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo
           sapiens]
          Length = 2524

 Score = 41.6 bits (96), Expect = 0.001
 Identities = 38/143 (26%), Positives = 55/143 (38%), Gaps = 24/143 (16%)

Query: 214 IAGLEENFHKEMSKLNQNLNDVLVG-----LEKQHGSNTFTVKAQPSDNAPAKGNKSPSP 268
           ++G EE   +E   L+ + N+V  G         + S+T ++ +  ++ A   G   P P
Sbjct: 710 VSGNEEEMVEEAEALHASGNEVPRGECSGPATVNNSSDTESIPSPHTEAAKDTGQNGPKP 769

Query: 269 P-----DGSPAATP-----EIRVNHEPEPAGGATPGATLPKSPSQPA---------EASE 309
           P     DG P   P     +I    EP PA  AT   T P +P  P+         E  E
Sbjct: 770 PATLGADGPPPGPPTPPPEDIPAPTEPTPASEATGAPTPPPAPPSPSAPPPVVPKEEKEE 829

Query: 310 VAGGTQPAAGAQEPGETAASEAA 332
                 P    +E    AA E A
Sbjct: 830 ETAAAPPVEEGEEQKPPAAEELA 852



 Score = 36.6 bits (83), Expect = 0.046
 Identities = 37/140 (26%), Positives = 54/140 (38%), Gaps = 10/140 (7%)

Query: 253 QPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQPAEASEVAG 312
           +P+  + A G  +P P   SP+A P +    E E    A P     +    PA A E+A 
Sbjct: 795 EPTPASEATGAPTPPPAPPSPSAPPPVVPKEEKEEETAAAPPVEEGEEQKPPA-AEELAV 853

Query: 313 GTQPAAGAQEPGETAASEAASSS-LPAVVVETFPATVNGTV-----EGGSGAGRLDLPPG 366
            T     A+EP ++  +E A          E   AT  G +     EGGSG        G
Sbjct: 854 DT---GKAEEPVKSECTEEAEEGPAKGKDAEAAEATAEGALKAEKKEGGSGRATTAKSSG 910

Query: 367 FMFKVQAQHDYTATDTDELQ 386
                 +    +A + DE +
Sbjct: 911 APQDSDSSATCSADEVDEAE 930


>gi|24308229 protein kinase C and casein kinase substrate in neurons
           1 [Homo sapiens]
          Length = 444

 Score = 41.6 bits (96), Expect = 0.001
 Identities = 70/288 (24%), Positives = 112/288 (38%), Gaps = 44/288 (15%)

Query: 164 KKKDEAKIAKAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHK 223
           +KK + K+ K ++++ K Q+ +E++  D+ +  P    +        F+     EE   K
Sbjct: 188 QKKLQDKVDKCKQDVQKTQEKYEKVLEDVGKTTPQYMENME----QVFEQCQQFEE---K 240

Query: 224 EMSKLNQNLNDVLVGLEKQHGSNTFTVKA---QPSDNAPAKGN----KSPSPPDGSPAAT 276
            +  L + L D+   L     S+   V     Q    A A+ +    +S S P G P   
Sbjct: 241 RLVFLKEVLLDIKRHLNLAENSSYIHVYRELEQAIRGADAQEDLRWFRSTSGP-GMPMNW 299

Query: 277 PEIRVNHEPEPAGGATPGATLPKSPSQPAEASEVAGGTQPAAGAQEPGETAASEAASSSL 336
           P+    +   P        T  K   QP +A  VA     A GA E    A    + SS 
Sbjct: 300 PQFEEWNPDLPH-------TTTKKEKQPKKAEGVA--LTNATGAVESTSQAGDRGSVSSY 350

Query: 337 PA--VVVETFPATVNGTVEGGS----GAGRLDLPPGFMFKVQAQHDYTATDTDELQLKAG 390
                    +    +G   GGS    GA   +       +V+A +DY   + DEL  KAG
Sbjct: 351 DRGQPYATEWSDDESGNPFGGSETNGGANPFE-DDSKGVRVRALYDYDGQEQDELSFKAG 409

Query: 391 DVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERV 438
           D +  +     EE ++GW  G  +S            G++P N+ E +
Sbjct: 410 DELTKL----GEEDEQGWCRGRLDSGQ---------LGLYPANYVEAI 444


>gi|219842343 glutamate receptor, metabotropic 5 isoform a precursor
            [Homo sapiens]
          Length = 1212

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 33/108 (30%), Positives = 45/108 (41%), Gaps = 14/108 (12%)

Query: 257  NAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQPAEASEVAGGTQP 316
            N+      +PSP  G+P  +  +       P     P      +  QP  A EV GG QP
Sbjct: 1076 NSMMLSTAAPSPGVGAPLCSSYLI------PKEIQLPTTMTTFAEIQPLPAIEVTGGAQP 1129

Query: 317  AAGAQEPGETA--------ASEAASSSLPAVVVETFPATVNGTVEGGS 356
            AAGAQ  G+ A         + AA   L  +V  T P+    +V+ GS
Sbjct: 1130 AAGAQAAGDAARESPAAGPEAAAAKPDLEELVALTPPSPFRDSVDSGS 1177


>gi|4504143 glutamate receptor, metabotropic 5 isoform b precursor
            [Homo sapiens]
          Length = 1180

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 33/108 (30%), Positives = 45/108 (41%), Gaps = 14/108 (12%)

Query: 257  NAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQPAEASEVAGGTQP 316
            N+      +PSP  G+P  +  +       P     P      +  QP  A EV GG QP
Sbjct: 1044 NSMMLSTAAPSPGVGAPLCSSYLI------PKEIQLPTTMTTFAEIQPLPAIEVTGGAQP 1097

Query: 317  AAGAQEPGETA--------ASEAASSSLPAVVVETFPATVNGTVEGGS 356
            AAGAQ  G+ A         + AA   L  +V  T P+    +V+ GS
Sbjct: 1098 AAGAQAAGDAARESPAAGPEAAAAKPDLEELVALTPPSPFRDSVDSGS 1145


>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
          Length = 1270

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 30/103 (29%), Positives = 40/103 (38%), Gaps = 8/103 (7%)

Query: 254 PSDNAPAKGNK-SPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQPAEASEVAG 312
           P + AP    K +P+ P+     TPE      PE     TP    P +P +PA  +  A 
Sbjct: 479 PKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAA 538

Query: 313 GTQPAAGAQEPGETAASEAASSS----LPAVVVETFPATVNGT 351
                   +EP  T   E A ++     P    ET P T  GT
Sbjct: 539 APNT---PKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGT 578



 Score = 33.9 bits (76), Expect = 0.30
 Identities = 24/90 (26%), Positives = 34/90 (37%), Gaps = 8/90 (8%)

Query: 258 APAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQPAEASEVAGGTQPA 317
           AP     +P+ P      TP+      P+     TP    P +P +PA  ++    T P 
Sbjct: 287 APTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTP- 345

Query: 318 AGAQEPGETAASEAASSSLPAVVVETFPAT 347
              +EP  TA  + A    P    E  P T
Sbjct: 346 ---KEPAPTAPKKPA----PTTPKEPAPTT 368



 Score = 33.5 bits (75), Expect = 0.39
 Identities = 31/110 (28%), Positives = 40/110 (36%), Gaps = 13/110 (11%)

Query: 251 KAQPSDNAP-AKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSP------SQ 303
           K    D AP +K    P+P   +    P +    EP P     P +T PK P      S 
Sbjct: 181 KTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSA 240

Query: 304 PAEASEVAGGTQPAAGA--QEPGETAASEAASSS----LPAVVVETFPAT 347
           P    E A  T  +A    +EP  T   E A ++     P    E  P T
Sbjct: 241 PTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTT 290



 Score = 33.5 bits (75), Expect = 0.39
 Identities = 32/107 (29%), Positives = 39/107 (36%), Gaps = 19/107 (17%)

Query: 249 TVKAQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSP------S 302
           T   +P+  AP K   +P+ P      TP+     EP P     P  T PK P      S
Sbjct: 343 TTPKEPAPTAPKK--PAPTTPKEPAPTTPK-----EPAPTTTKEPSPTTPKEPAPTTTKS 395

Query: 303 QPAEASEVAGGTQPAAGA--QEPGETAASEAASSSLPAVVVETFPAT 347
            P    E A  T  +A    +EP  T   E A    P    E  P T
Sbjct: 396 APTTTKEPAPTTTKSAPTTPKEPSPTTTKEPA----PTTPKEPAPTT 438



 Score = 32.7 bits (73), Expect = 0.67
 Identities = 29/105 (27%), Positives = 42/105 (40%), Gaps = 9/105 (8%)

Query: 249 TVKAQPS---DNAPAKGNKSPSPP-DGSPAAT--PEIRVNHEPEPAGGATPGATLPK--S 300
           T K+ P+   + AP     +P+ P + SP  T  P      EP P     P  T PK  +
Sbjct: 392 TTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPA 451

Query: 301 PSQPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFP 345
           P+ P E +            +EP  T   E A ++ P  +  T P
Sbjct: 452 PTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTT-PKKLTPTTP 495



 Score = 32.0 bits (71), Expect = 1.1
 Identities = 27/94 (28%), Positives = 37/94 (39%), Gaps = 12/94 (12%)

Query: 249 TVKAQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQPAE-- 306
           T   +P+   P    K P+P + +P  T E       +PA   TP  T P +P +PA   
Sbjct: 581 TTLKEPAPTTP----KKPAPKELAPTTTKEPTSTTCDKPAP-TTPKGTAPTTPKEPAPTT 635

Query: 307 ----ASEVAGGTQPAAGAQEPGETAASEAASSSL 336
               A     GT P    +EP  T   + A   L
Sbjct: 636 PKEPAPTTPKGTAPTT-LKEPAPTTPKKPAPKEL 668



 Score = 32.0 bits (71), Expect = 1.1
 Identities = 23/85 (27%), Positives = 34/85 (40%), Gaps = 6/85 (7%)

Query: 265 SPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQPAEASEVAGGTQPAAGAQEPG 324
           +P+ P G+   TP+      P+     TP  T P +  +PA  +      +PA     P 
Sbjct: 616 APTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTP----KKPAPKELAPT 671

Query: 325 ETAASEAASSSLPAVVV--ETFPAT 347
            T    + +S  PA     ET P T
Sbjct: 672 TTKGPTSTTSDKPAPTTPKETAPTT 696



 Score = 30.8 bits (68), Expect = 2.5
 Identities = 24/104 (23%), Positives = 35/104 (33%), Gaps = 5/104 (4%)

Query: 249 TVKAQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQPAEAS 308
           T   +P+         +P  P  +    P      EP P     P  T PK P+   +  
Sbjct: 281 TTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEP 340

Query: 309 EVAGGTQPAAGA-QEPGETAASEAASSS----LPAVVVETFPAT 347
                 +PA  A ++P  T   E A ++     P    E  P T
Sbjct: 341 APTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTT 384



 Score = 29.6 bits (65), Expect = 5.7
 Identities = 30/103 (29%), Positives = 37/103 (35%), Gaps = 11/103 (10%)

Query: 254 PSDNAPAKGNKSPSPPDGSPAAT----PEIRVNHEPEPAGGATPGATLPKSPSQPAEASE 309
           P + AP     +P+ P   PA T    P      EP P     P  T  K PS P    E
Sbjct: 330 PKEPAPTTKEPAPTTPK-EPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPS-PTTPKE 387

Query: 310 VAGGTQPAA--GAQEPGETAASEAASS---SLPAVVVETFPAT 347
            A  T  +A    +EP  T    A ++     P    E  P T
Sbjct: 388 PAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTT 430



 Score = 29.3 bits (64), Expect = 7.4
 Identities = 24/101 (23%), Positives = 34/101 (33%), Gaps = 7/101 (6%)

Query: 254 PSDNAPAKGNKSPSPP-DGSPAATPEIRVN-HEPEPAGGATPGATLPKSPS-----QPAE 306
           P +  P     +P+ P + +P  T        EP P     P  T PK P+     +PA 
Sbjct: 229 PKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAP 288

Query: 307 ASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPAT 347
            +  +  T P   A    +  A        P    E  P T
Sbjct: 289 TTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTT 329



 Score = 28.9 bits (63), Expect = 9.7
 Identities = 26/98 (26%), Positives = 34/98 (34%), Gaps = 8/98 (8%)

Query: 254 PSDNAPAKGNKSPSPP-DGSPAAT--PEIRVNHEPEPAGGATPGATLPKS-PSQPAEASE 309
           P + AP     +P+ P + +P  T  P      EP P     P  T  KS P+ P E + 
Sbjct: 244 PKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAP 303

Query: 310 VAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPAT 347
                      +EP  T   E      P    E  P T
Sbjct: 304 TTPKKPAPTTPKEPAPTTPKEPT----PTTPKEPAPTT 337


>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
          Length = 1311

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 30/103 (29%), Positives = 40/103 (38%), Gaps = 8/103 (7%)

Query: 254 PSDNAPAKGNK-SPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQPAEASEVAG 312
           P + AP    K +P+ P+     TPE      PE     TP    P +P +PA  +  A 
Sbjct: 520 PKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAA 579

Query: 313 GTQPAAGAQEPGETAASEAASSS----LPAVVVETFPATVNGT 351
                   +EP  T   E A ++     P    ET P T  GT
Sbjct: 580 APNT---PKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGT 619



 Score = 33.9 bits (76), Expect = 0.30
 Identities = 24/90 (26%), Positives = 34/90 (37%), Gaps = 8/90 (8%)

Query: 258 APAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQPAEASEVAGGTQPA 317
           AP     +P+ P      TP+      P+     TP    P +P +PA  ++    T P 
Sbjct: 328 APTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTP- 386

Query: 318 AGAQEPGETAASEAASSSLPAVVVETFPAT 347
              +EP  TA  + A    P    E  P T
Sbjct: 387 ---KEPAPTAPKKPA----PTTPKEPAPTT 409



 Score = 33.5 bits (75), Expect = 0.39
 Identities = 31/110 (28%), Positives = 40/110 (36%), Gaps = 13/110 (11%)

Query: 251 KAQPSDNAP-AKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSP------SQ 303
           K    D AP +K    P+P   +    P +    EP P     P +T PK P      S 
Sbjct: 222 KTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSA 281

Query: 304 PAEASEVAGGTQPAAGA--QEPGETAASEAASSS----LPAVVVETFPAT 347
           P    E A  T  +A    +EP  T   E A ++     P    E  P T
Sbjct: 282 PTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTT 331



 Score = 33.5 bits (75), Expect = 0.39
 Identities = 32/107 (29%), Positives = 39/107 (36%), Gaps = 19/107 (17%)

Query: 249 TVKAQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSP------S 302
           T   +P+  AP K   +P+ P      TP+     EP P     P  T PK P      S
Sbjct: 384 TTPKEPAPTAPKK--PAPTTPKEPAPTTPK-----EPAPTTTKEPSPTTPKEPAPTTTKS 436

Query: 303 QPAEASEVAGGTQPAAGA--QEPGETAASEAASSSLPAVVVETFPAT 347
            P    E A  T  +A    +EP  T   E A    P    E  P T
Sbjct: 437 APTTTKEPAPTTTKSAPTTPKEPSPTTTKEPA----PTTPKEPAPTT 479



 Score = 32.7 bits (73), Expect = 0.67
 Identities = 29/105 (27%), Positives = 42/105 (40%), Gaps = 9/105 (8%)

Query: 249 TVKAQPS---DNAPAKGNKSPSPP-DGSPAAT--PEIRVNHEPEPAGGATPGATLPK--S 300
           T K+ P+   + AP     +P+ P + SP  T  P      EP P     P  T PK  +
Sbjct: 433 TTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPA 492

Query: 301 PSQPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFP 345
           P+ P E +            +EP  T   E A ++ P  +  T P
Sbjct: 493 PTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTT-PKKLTPTTP 536



 Score = 32.0 bits (71), Expect = 1.1
 Identities = 27/94 (28%), Positives = 37/94 (39%), Gaps = 12/94 (12%)

Query: 249 TVKAQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQPAE-- 306
           T   +P+   P    K P+P + +P  T E       +PA   TP  T P +P +PA   
Sbjct: 622 TTLKEPAPTTP----KKPAPKELAPTTTKEPTSTTCDKPAP-TTPKGTAPTTPKEPAPTT 676

Query: 307 ----ASEVAGGTQPAAGAQEPGETAASEAASSSL 336
               A     GT P    +EP  T   + A   L
Sbjct: 677 PKEPAPTTPKGTAPTT-LKEPAPTTPKKPAPKEL 709



 Score = 32.0 bits (71), Expect = 1.1
 Identities = 23/85 (27%), Positives = 34/85 (40%), Gaps = 6/85 (7%)

Query: 265 SPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQPAEASEVAGGTQPAAGAQEPG 324
           +P+ P G+   TP+      P+     TP  T P +  +PA  +      +PA     P 
Sbjct: 657 APTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTP----KKPAPKELAPT 712

Query: 325 ETAASEAASSSLPAVVV--ETFPAT 347
            T    + +S  PA     ET P T
Sbjct: 713 TTKGPTSTTSDKPAPTTPKETAPTT 737



 Score = 30.8 bits (68), Expect = 2.5
 Identities = 24/104 (23%), Positives = 35/104 (33%), Gaps = 5/104 (4%)

Query: 249 TVKAQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQPAEAS 308
           T   +P+         +P  P  +    P      EP P     P  T PK P+   +  
Sbjct: 322 TTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEP 381

Query: 309 EVAGGTQPAAGA-QEPGETAASEAASSS----LPAVVVETFPAT 347
                 +PA  A ++P  T   E A ++     P    E  P T
Sbjct: 382 APTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTT 425



 Score = 29.6 bits (65), Expect = 5.7
 Identities = 30/103 (29%), Positives = 37/103 (35%), Gaps = 11/103 (10%)

Query: 254 PSDNAPAKGNKSPSPPDGSPAAT----PEIRVNHEPEPAGGATPGATLPKSPSQPAEASE 309
           P + AP     +P+ P   PA T    P      EP P     P  T  K PS P    E
Sbjct: 371 PKEPAPTTKEPAPTTPK-EPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPS-PTTPKE 428

Query: 310 VAGGTQPAA--GAQEPGETAASEAASS---SLPAVVVETFPAT 347
            A  T  +A    +EP  T    A ++     P    E  P T
Sbjct: 429 PAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTT 471



 Score = 29.3 bits (64), Expect = 7.4
 Identities = 24/101 (23%), Positives = 34/101 (33%), Gaps = 7/101 (6%)

Query: 254 PSDNAPAKGNKSPSPP-DGSPAATPEIRVN-HEPEPAGGATPGATLPKSPS-----QPAE 306
           P +  P     +P+ P + +P  T        EP P     P  T PK P+     +PA 
Sbjct: 270 PKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAP 329

Query: 307 ASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPAT 347
            +  +  T P   A    +  A        P    E  P T
Sbjct: 330 TTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTT 370



 Score = 28.9 bits (63), Expect = 9.7
 Identities = 26/98 (26%), Positives = 34/98 (34%), Gaps = 8/98 (8%)

Query: 254 PSDNAPAKGNKSPSPP-DGSPAAT--PEIRVNHEPEPAGGATPGATLPKS-PSQPAEASE 309
           P + AP     +P+ P + +P  T  P      EP P     P  T  KS P+ P E + 
Sbjct: 285 PKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAP 344

Query: 310 VAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPAT 347
                      +EP  T   E      P    E  P T
Sbjct: 345 TTPKKPAPTTPKEPAPTTPKEPT----PTTPKEPAPTT 378


>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
          Length = 1363

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 30/103 (29%), Positives = 40/103 (38%), Gaps = 8/103 (7%)

Query: 254 PSDNAPAKGNK-SPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQPAEASEVAG 312
           P + AP    K +P+ P+     TPE      PE     TP    P +P +PA  +  A 
Sbjct: 572 PKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAA 631

Query: 313 GTQPAAGAQEPGETAASEAASSS----LPAVVVETFPATVNGT 351
                   +EP  T   E A ++     P    ET P T  GT
Sbjct: 632 APNT---PKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGT 671



 Score = 33.9 bits (76), Expect = 0.30
 Identities = 24/90 (26%), Positives = 34/90 (37%), Gaps = 8/90 (8%)

Query: 258 APAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQPAEASEVAGGTQPA 317
           AP     +P+ P      TP+      P+     TP    P +P +PA  ++    T P 
Sbjct: 380 APTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTP- 438

Query: 318 AGAQEPGETAASEAASSSLPAVVVETFPAT 347
              +EP  TA  + A    P    E  P T
Sbjct: 439 ---KEPAPTAPKKPA----PTTPKEPAPTT 461



 Score = 33.5 bits (75), Expect = 0.39
 Identities = 31/110 (28%), Positives = 40/110 (36%), Gaps = 13/110 (11%)

Query: 251 KAQPSDNAP-AKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSP------SQ 303
           K    D AP +K    P+P   +    P +    EP P     P +T PK P      S 
Sbjct: 274 KTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSA 333

Query: 304 PAEASEVAGGTQPAAGA--QEPGETAASEAASSS----LPAVVVETFPAT 347
           P    E A  T  +A    +EP  T   E A ++     P    E  P T
Sbjct: 334 PTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTT 383



 Score = 33.5 bits (75), Expect = 0.39
 Identities = 32/107 (29%), Positives = 39/107 (36%), Gaps = 19/107 (17%)

Query: 249 TVKAQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSP------S 302
           T   +P+  AP K   +P+ P      TP+     EP P     P  T PK P      S
Sbjct: 436 TTPKEPAPTAPKK--PAPTTPKEPAPTTPK-----EPAPTTTKEPSPTTPKEPAPTTTKS 488

Query: 303 QPAEASEVAGGTQPAAGA--QEPGETAASEAASSSLPAVVVETFPAT 347
            P    E A  T  +A    +EP  T   E A    P    E  P T
Sbjct: 489 APTTTKEPAPTTTKSAPTTPKEPSPTTTKEPA----PTTPKEPAPTT 531



 Score = 32.7 bits (73), Expect = 0.67
 Identities = 29/105 (27%), Positives = 42/105 (40%), Gaps = 9/105 (8%)

Query: 249 TVKAQPS---DNAPAKGNKSPSPP-DGSPAAT--PEIRVNHEPEPAGGATPGATLPK--S 300
           T K+ P+   + AP     +P+ P + SP  T  P      EP P     P  T PK  +
Sbjct: 485 TTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPA 544

Query: 301 PSQPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFP 345
           P+ P E +            +EP  T   E A ++ P  +  T P
Sbjct: 545 PTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTT-PKKLTPTTP 588



 Score = 32.0 bits (71), Expect = 1.1
 Identities = 27/94 (28%), Positives = 37/94 (39%), Gaps = 12/94 (12%)

Query: 249 TVKAQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQPAE-- 306
           T   +P+   P    K P+P + +P  T E       +PA   TP  T P +P +PA   
Sbjct: 674 TTLKEPAPTTP----KKPAPKELAPTTTKEPTSTTCDKPAP-TTPKGTAPTTPKEPAPTT 728

Query: 307 ----ASEVAGGTQPAAGAQEPGETAASEAASSSL 336
               A     GT P    +EP  T   + A   L
Sbjct: 729 PKEPAPTTPKGTAPTT-LKEPAPTTPKKPAPKEL 761



 Score = 32.0 bits (71), Expect = 1.1
 Identities = 23/85 (27%), Positives = 34/85 (40%), Gaps = 6/85 (7%)

Query: 265 SPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQPAEASEVAGGTQPAAGAQEPG 324
           +P+ P G+   TP+      P+     TP  T P +  +PA  +      +PA     P 
Sbjct: 709 APTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTP----KKPAPKELAPT 764

Query: 325 ETAASEAASSSLPAVVV--ETFPAT 347
            T    + +S  PA     ET P T
Sbjct: 765 TTKGPTSTTSDKPAPTTPKETAPTT 789



 Score = 30.8 bits (68), Expect = 2.5
 Identities = 24/104 (23%), Positives = 35/104 (33%), Gaps = 5/104 (4%)

Query: 249 TVKAQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQPAEAS 308
           T   +P+         +P  P  +    P      EP P     P  T PK P+   +  
Sbjct: 374 TTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEP 433

Query: 309 EVAGGTQPAAGA-QEPGETAASEAASSS----LPAVVVETFPAT 347
                 +PA  A ++P  T   E A ++     P    E  P T
Sbjct: 434 APTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTT 477



 Score = 29.6 bits (65), Expect = 5.7
 Identities = 30/103 (29%), Positives = 37/103 (35%), Gaps = 11/103 (10%)

Query: 254 PSDNAPAKGNKSPSPPDGSPAAT----PEIRVNHEPEPAGGATPGATLPKSPSQPAEASE 309
           P + AP     +P+ P   PA T    P      EP P     P  T  K PS P    E
Sbjct: 423 PKEPAPTTKEPAPTTPK-EPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPS-PTTPKE 480

Query: 310 VAGGTQPAA--GAQEPGETAASEAASS---SLPAVVVETFPAT 347
            A  T  +A    +EP  T    A ++     P    E  P T
Sbjct: 481 PAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTT 523



 Score = 29.3 bits (64), Expect = 7.4
 Identities = 24/101 (23%), Positives = 34/101 (33%), Gaps = 7/101 (6%)

Query: 254 PSDNAPAKGNKSPSPP-DGSPAATPEIRVN-HEPEPAGGATPGATLPKSPS-----QPAE 306
           P +  P     +P+ P + +P  T        EP P     P  T PK P+     +PA 
Sbjct: 322 PKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAP 381

Query: 307 ASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPAT 347
            +  +  T P   A    +  A        P    E  P T
Sbjct: 382 TTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTT 422



 Score = 28.9 bits (63), Expect = 9.7
 Identities = 26/98 (26%), Positives = 34/98 (34%), Gaps = 8/98 (8%)

Query: 254 PSDNAPAKGNKSPSPP-DGSPAAT--PEIRVNHEPEPAGGATPGATLPKS-PSQPAEASE 309
           P + AP     +P+ P + +P  T  P      EP P     P  T  KS P+ P E + 
Sbjct: 337 PKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAP 396

Query: 310 VAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPAT 347
                      +EP  T   E      P    E  P T
Sbjct: 397 TTPKKPAPTTPKEPAPTTPKEPT----PTTPKEPAPTT 430


>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
          Length = 1404

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 30/103 (29%), Positives = 40/103 (38%), Gaps = 8/103 (7%)

Query: 254 PSDNAPAKGNK-SPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQPAEASEVAG 312
           P + AP    K +P+ P+     TPE      PE     TP    P +P +PA  +  A 
Sbjct: 613 PKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAA 672

Query: 313 GTQPAAGAQEPGETAASEAASSS----LPAVVVETFPATVNGT 351
                   +EP  T   E A ++     P    ET P T  GT
Sbjct: 673 APNT---PKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGT 712



 Score = 33.9 bits (76), Expect = 0.30
 Identities = 24/90 (26%), Positives = 34/90 (37%), Gaps = 8/90 (8%)

Query: 258 APAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQPAEASEVAGGTQPA 317
           AP     +P+ P      TP+      P+     TP    P +P +PA  ++    T P 
Sbjct: 421 APTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTP- 479

Query: 318 AGAQEPGETAASEAASSSLPAVVVETFPAT 347
              +EP  TA  + A    P    E  P T
Sbjct: 480 ---KEPAPTAPKKPA----PTTPKEPAPTT 502



 Score = 33.5 bits (75), Expect = 0.39
 Identities = 31/110 (28%), Positives = 40/110 (36%), Gaps = 13/110 (11%)

Query: 251 KAQPSDNAP-AKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSP------SQ 303
           K    D AP +K    P+P   +    P +    EP P     P +T PK P      S 
Sbjct: 315 KTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSA 374

Query: 304 PAEASEVAGGTQPAAGA--QEPGETAASEAASSS----LPAVVVETFPAT 347
           P    E A  T  +A    +EP  T   E A ++     P    E  P T
Sbjct: 375 PTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTT 424



 Score = 33.5 bits (75), Expect = 0.39
 Identities = 32/107 (29%), Positives = 39/107 (36%), Gaps = 19/107 (17%)

Query: 249 TVKAQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSP------S 302
           T   +P+  AP K   +P+ P      TP+     EP P     P  T PK P      S
Sbjct: 477 TTPKEPAPTAPKK--PAPTTPKEPAPTTPK-----EPAPTTTKEPSPTTPKEPAPTTTKS 529

Query: 303 QPAEASEVAGGTQPAAGA--QEPGETAASEAASSSLPAVVVETFPAT 347
            P    E A  T  +A    +EP  T   E A    P    E  P T
Sbjct: 530 APTTTKEPAPTTTKSAPTTPKEPSPTTTKEPA----PTTPKEPAPTT 572



 Score = 32.7 bits (73), Expect = 0.67
 Identities = 29/105 (27%), Positives = 42/105 (40%), Gaps = 9/105 (8%)

Query: 249 TVKAQPS---DNAPAKGNKSPSPP-DGSPAAT--PEIRVNHEPEPAGGATPGATLPK--S 300
           T K+ P+   + AP     +P+ P + SP  T  P      EP P     P  T PK  +
Sbjct: 526 TTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPA 585

Query: 301 PSQPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFP 345
           P+ P E +            +EP  T   E A ++ P  +  T P
Sbjct: 586 PTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTT-PKKLTPTTP 629



 Score = 32.0 bits (71), Expect = 1.1
 Identities = 27/94 (28%), Positives = 37/94 (39%), Gaps = 12/94 (12%)

Query: 249 TVKAQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQPAE-- 306
           T   +P+   P    K P+P + +P  T E       +PA   TP  T P +P +PA   
Sbjct: 715 TTLKEPAPTTP----KKPAPKELAPTTTKEPTSTTCDKPAP-TTPKGTAPTTPKEPAPTT 769

Query: 307 ----ASEVAGGTQPAAGAQEPGETAASEAASSSL 336
               A     GT P    +EP  T   + A   L
Sbjct: 770 PKEPAPTTPKGTAPTT-LKEPAPTTPKKPAPKEL 802



 Score = 32.0 bits (71), Expect = 1.1
 Identities = 23/85 (27%), Positives = 34/85 (40%), Gaps = 6/85 (7%)

Query: 265 SPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQPAEASEVAGGTQPAAGAQEPG 324
           +P+ P G+   TP+      P+     TP  T P +  +PA  +      +PA     P 
Sbjct: 750 APTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTP----KKPAPKELAPT 805

Query: 325 ETAASEAASSSLPAVVV--ETFPAT 347
            T    + +S  PA     ET P T
Sbjct: 806 TTKGPTSTTSDKPAPTTPKETAPTT 830



 Score = 30.8 bits (68), Expect = 2.5
 Identities = 24/104 (23%), Positives = 35/104 (33%), Gaps = 5/104 (4%)

Query: 249 TVKAQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQPAEAS 308
           T   +P+         +P  P  +    P      EP P     P  T PK P+   +  
Sbjct: 415 TTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEP 474

Query: 309 EVAGGTQPAAGA-QEPGETAASEAASSS----LPAVVVETFPAT 347
                 +PA  A ++P  T   E A ++     P    E  P T
Sbjct: 475 APTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTT 518



 Score = 29.6 bits (65), Expect = 5.7
 Identities = 30/103 (29%), Positives = 37/103 (35%), Gaps = 11/103 (10%)

Query: 254 PSDNAPAKGNKSPSPPDGSPAAT----PEIRVNHEPEPAGGATPGATLPKSPSQPAEASE 309
           P + AP     +P+ P   PA T    P      EP P     P  T  K PS P    E
Sbjct: 464 PKEPAPTTKEPAPTTPK-EPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPS-PTTPKE 521

Query: 310 VAGGTQPAA--GAQEPGETAASEAASS---SLPAVVVETFPAT 347
            A  T  +A    +EP  T    A ++     P    E  P T
Sbjct: 522 PAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTT 564



 Score = 29.3 bits (64), Expect = 7.4
 Identities = 24/101 (23%), Positives = 34/101 (33%), Gaps = 7/101 (6%)

Query: 254 PSDNAPAKGNKSPSPP-DGSPAATPEIRVN-HEPEPAGGATPGATLPKSPS-----QPAE 306
           P +  P     +P+ P + +P  T        EP P     P  T PK P+     +PA 
Sbjct: 363 PKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAP 422

Query: 307 ASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPAT 347
            +  +  T P   A    +  A        P    E  P T
Sbjct: 423 TTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTT 463



 Score = 28.9 bits (63), Expect = 9.7
 Identities = 26/98 (26%), Positives = 34/98 (34%), Gaps = 8/98 (8%)

Query: 254 PSDNAPAKGNKSPSPP-DGSPAAT--PEIRVNHEPEPAGGATPGATLPKS-PSQPAEASE 309
           P + AP     +P+ P + +P  T  P      EP P     P  T  KS P+ P E + 
Sbjct: 378 PKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAP 437

Query: 310 VAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPAT 347
                      +EP  T   E      P    E  P T
Sbjct: 438 TTPKKPAPTTPKEPAPTTPKEPT----PTTPKEPAPTT 471


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.309    0.127    0.363 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,308,465
Number of Sequences: 37866
Number of extensions: 980751
Number of successful extensions: 8350
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 140
Number of HSP's successfully gapped in prelim test: 785
Number of HSP's that attempted gapping in prelim test: 6462
Number of HSP's gapped (non-prelim): 2388
length of query: 439
length of database: 18,247,518
effective HSP length: 105
effective length of query: 334
effective length of database: 14,271,588
effective search space: 4766710392
effective search space used: 4766710392
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.