Guide to the Human Genome
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Search of human proteins with 21536400

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|21536400 bridging integrator 1 isoform 1 [Homo sapiens]
         (593 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|21536400 bridging integrator 1 isoform 1 [Homo sapiens]           1201   0.0  
gi|21536402 bridging integrator 1 isoform 2 [Homo sapiens]           1093   0.0  
gi|21536409 bridging integrator 1 isoform 5 [Homo sapiens]           1008   0.0  
gi|21536404 bridging integrator 1 isoform 3 [Homo sapiens]            881   0.0  
gi|21536411 bridging integrator 1 isoform 6 [Homo sapiens]            867   0.0  
gi|21536407 bridging integrator 1 isoform 4 [Homo sapiens]            857   0.0  
gi|21536413 bridging integrator 1 isoform 7 [Homo sapiens]            819   0.0  
gi|21536415 bridging integrator 1 isoform 9 [Homo sapiens]            595   e-170
gi|21536417 bridging integrator 1 isoform 10 [Homo sapiens]           593   e-169
gi|4757748 bridging integrator 1 isoform 8 [Homo sapiens]             585   e-167
gi|4502081 amphiphysin isoform 1 [Homo sapiens]                       461   e-130
gi|21536423 amphiphysin isoform 2 [Homo sapiens]                      461   e-129
gi|49472835 bridging integrator 2 [Homo sapiens]                      313   4e-85
gi|163965366 nascent polypeptide-associated complex alpha subuni...    61   3e-09
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    59   1e-08
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    59   1e-08
gi|149773456 hypothetical protein LOC643314 [Homo sapiens]             57   5e-08
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    53   7e-07
gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Hom...    52   2e-06
gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Hom...    52   2e-06
gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo sap...    52   2e-06
gi|189181724 proteoglycan 4 isoform D [Homo sapiens]                   51   3e-06
gi|189181722 proteoglycan 4 isoform C [Homo sapiens]                   51   3e-06
gi|189181720 proteoglycan 4 isoform B [Homo sapiens]                   51   3e-06
gi|67190163 proteoglycan 4 isoform A [Homo sapiens]                    51   3e-06
gi|47132519 Ras association and pleckstrin homology domains 1 is...    51   3e-06
gi|112734870 hypothetical protein LOC57648 [Homo sapiens]              51   3e-06
gi|116284392 mucin 2 precursor [Homo sapiens]                          50   4e-06
gi|222418647 mucin 7, secreted precursor [Homo sapiens]                49   1e-05
gi|222418649 mucin 7, secreted precursor [Homo sapiens]                49   1e-05

>gi|21536400 bridging integrator 1 isoform 1 [Homo sapiens]
          Length = 593

 Score = 1201 bits (3107), Expect = 0.0
 Identities = 593/593 (100%), Positives = 593/593 (100%)

Query: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60
           MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR
Sbjct: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60

Query: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120
           LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD
Sbjct: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120

Query: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKPVSLLEK 180
           QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKPVSLLEK
Sbjct: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKPVSLLEK 180

Query: 181 AAPQWCQGKLQAHLVAQTNLLRNQAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN 240
           AAPQWCQGKLQAHLVAQTNLLRNQAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN
Sbjct: 181 AAPQWCQGKLQAHLVAQTNLLRNQAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN 240

Query: 241 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP 300
           TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP
Sbjct: 241 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP 300

Query: 301 DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPPPKHTPSKEVKQEQILS 360
           DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPPPKHTPSKEVKQEQILS
Sbjct: 301 DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPPPKHTPSKEVKQEQILS 360

Query: 361 LFEDTFVPEISVTTPSQFEAPGPFSEQASLLDLDFDPLPPVTSPVKAPTPSGQSIPWDLW 420
           LFEDTFVPEISVTTPSQFEAPGPFSEQASLLDLDFDPLPPVTSPVKAPTPSGQSIPWDLW
Sbjct: 361 LFEDTFVPEISVTTPSQFEAPGPFSEQASLLDLDFDPLPPVTSPVKAPTPSGQSIPWDLW 420

Query: 421 EPTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGET 480
           EPTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGET
Sbjct: 421 EPTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGET 480

Query: 481 AASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQ 540
           AASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQ
Sbjct: 481 AASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQ 540

Query: 541 LKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERVP 593
           LKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERVP
Sbjct: 541 LKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERVP 593


>gi|21536402 bridging integrator 1 isoform 2 [Homo sapiens]
          Length = 550

 Score = 1093 bits (2826), Expect = 0.0
 Identities = 550/593 (92%), Positives = 550/593 (92%), Gaps = 43/593 (7%)

Query: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60
           MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR
Sbjct: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60

Query: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120
           LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD
Sbjct: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120

Query: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKPVSLLEK 180
           QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKPVSLLEK
Sbjct: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKPVSLLEK 180

Query: 181 AAPQWCQGKLQAHLVAQTNLLRNQAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN 240
           AAPQWCQGKLQAHLVAQTNLLRNQAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN
Sbjct: 181 AAPQWCQGKLQAHLVAQTNLLRNQAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN 240

Query: 241 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP 300
           TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP
Sbjct: 241 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP 300

Query: 301 DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPPPKHTPSKEVKQEQILS 360
           DGSPAATPEIRVNHEPEPAGGATPGATLPKSPS                           
Sbjct: 301 DGSPAATPEIRVNHEPEPAGGATPGATLPKSPS--------------------------- 333

Query: 361 LFEDTFVPEISVTTPSQFEAPGPFSEQASLLDLDFDPLPPVTSPVKAPTPSGQSIPWDLW 420
                           QFEAPGPFSEQASLLDLDFDPLPPVTSPVKAPTPSGQSIPWDLW
Sbjct: 334 ----------------QFEAPGPFSEQASLLDLDFDPLPPVTSPVKAPTPSGQSIPWDLW 377

Query: 421 EPTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGET 480
           EPTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGET
Sbjct: 378 EPTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGET 437

Query: 481 AASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQ 540
           AASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQ
Sbjct: 438 AASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQ 497

Query: 541 LKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERVP 593
           LKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERVP
Sbjct: 498 LKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERVP 550


>gi|21536409 bridging integrator 1 isoform 5 [Homo sapiens]
          Length = 518

 Score = 1008 bits (2605), Expect = 0.0
 Identities = 518/593 (87%), Positives = 518/593 (87%), Gaps = 75/593 (12%)

Query: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60
           MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR
Sbjct: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60

Query: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120
           LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD
Sbjct: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120

Query: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKPVSLLEK 180
           QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAK       
Sbjct: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAK------- 173

Query: 181 AAPQWCQGKLQAHLVAQTNLLRNQAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN 240
                                   AEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN
Sbjct: 174 ------------------------AEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN 209

Query: 241 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP 300
           TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP
Sbjct: 210 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP 269

Query: 301 DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPPPKHTPSKEVKQEQILS 360
           DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPPPKHTPSKEVKQEQILS
Sbjct: 270 DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPPPKHTPSKEVKQEQILS 329

Query: 361 LFEDTFVPEISVTTPSQFEAPGPFSEQASLLDLDFDPLPPVTSPVKAPTPSGQSIPWDLW 420
           LFEDTFVPEISVTTPSQ                                           
Sbjct: 330 LFEDTFVPEISVTTPSQ------------------------------------------- 346

Query: 421 EPTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGET 480
            PTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGET
Sbjct: 347 -PTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGET 405

Query: 481 AASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQ 540
           AASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQ
Sbjct: 406 AASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQ 465

Query: 541 LKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERVP 593
           LKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERVP
Sbjct: 466 LKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERVP 518


>gi|21536404 bridging integrator 1 isoform 3 [Homo sapiens]
          Length = 506

 Score =  881 bits (2276), Expect = 0.0
 Identities = 469/593 (79%), Positives = 477/593 (80%), Gaps = 87/593 (14%)

Query: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60
           MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR
Sbjct: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60

Query: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120
           LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD
Sbjct: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120

Query: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKPVSLLEK 180
           QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKPVSLLEK
Sbjct: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKPVSLLEK 180

Query: 181 AAPQWCQGKLQAHLVAQTNLLRNQAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN 240
           AAPQWCQGKLQAHLVAQTNLLRNQAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN
Sbjct: 181 AAPQWCQGKLQAHLVAQTNLLRNQAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN 240

Query: 241 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP 300
           TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP
Sbjct: 241 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP 300

Query: 301 DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPPPKHTPSKEVKQEQILS 360
           DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQ     P   P    PS E       S
Sbjct: 301 DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQ-----PTESPAGSLPSGEP------S 349

Query: 361 LFEDTFVPEISVTTPSQFEAPGPFSEQASLLDLDFDPLPPVTSPVKAPTPSGQSIPWDLW 420
             E TF    +V+ PSQ   PGP                    P +A   +G        
Sbjct: 350 AAEGTF----AVSWPSQTAEPGP------------------AQPAEASEVAG-------- 379

Query: 421 EPTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGET 480
             T+  AG+   GE +A+E                                         
Sbjct: 380 -GTQPAAGAQEPGETAASE----------------------------------------- 397

Query: 481 AASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQ 540
               AASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQ
Sbjct: 398 ----AASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQ 453

Query: 541 LKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERVP 593
           LKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERVP
Sbjct: 454 LKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERVP 506


>gi|21536411 bridging integrator 1 isoform 6 [Homo sapiens]
          Length = 482

 Score =  867 bits (2239), Expect = 0.0
 Identities = 462/593 (77%), Positives = 466/593 (78%), Gaps = 111/593 (18%)

Query: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60
           MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR
Sbjct: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60

Query: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120
           LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD
Sbjct: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120

Query: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKPVSLLEK 180
           QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAK       
Sbjct: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAK------- 173

Query: 181 AAPQWCQGKLQAHLVAQTNLLRNQAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN 240
                                   AEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN
Sbjct: 174 ------------------------AEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN 209

Query: 241 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP 300
           TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP
Sbjct: 210 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP 269

Query: 301 DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPPPKHTPSKEVKQEQILS 360
           DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPPPKHTPSKEVKQEQILS
Sbjct: 270 DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPPPKHTPSKEVKQEQILS 329

Query: 361 LFEDTFVPEISVTTPSQFEAPGPFSEQASLLDLDFDPLPPVTSPVKAPTPSGQSIPWDLW 420
           LFEDTFVPEISVTTPSQ   P   SE A                                
Sbjct: 330 LFEDTFVPEISVTTPSQ---PAEASEVAG------------------------------- 355

Query: 421 EPTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGET 480
             T+  AG+   GE +                        ASE A  + PA         
Sbjct: 356 -GTQPAAGAQEPGETA------------------------ASEAASSSLPA--------- 381

Query: 481 AASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQ 540
                       VVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQ
Sbjct: 382 ------------VVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQ 429

Query: 541 LKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERVP 593
           LKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERVP
Sbjct: 430 LKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERVP 482


>gi|21536407 bridging integrator 1 isoform 4 [Homo sapiens]
          Length = 497

 Score =  857 bits (2213), Expect = 0.0
 Identities = 462/608 (75%), Positives = 466/608 (76%), Gaps = 126/608 (20%)

Query: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60
           MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR
Sbjct: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60

Query: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120
           LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD
Sbjct: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120

Query: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKPVSLLEK 180
           QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAK       
Sbjct: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAK------- 173

Query: 181 AAPQWCQGKLQAHLVAQTNLLRNQAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN 240
                                   AEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN
Sbjct: 174 ------------------------AEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN 209

Query: 241 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQP--------------- 285
           TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQP               
Sbjct: 210 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPRKKSKLFSRLRRKKN 269

Query: 286 SDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPPP 345
           SDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPPP
Sbjct: 270 SDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPPP 329

Query: 346 KHTPSKEVKQEQILSLFEDTFVPEISVTTPSQFEAPGPFSEQASLLDLDFDPLPPVTSPV 405
           KHTPSKEVKQEQILSLFEDTFVPEISVTTPSQ   P   SE A                 
Sbjct: 330 KHTPSKEVKQEQILSLFEDTFVPEISVTTPSQ---PAEASEVAG---------------- 370

Query: 406 KAPTPSGQSIPWDLWEPTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEASEVA 465
                            T+  AG+   GE +                        ASE A
Sbjct: 371 ----------------GTQPAAGAQEPGETA------------------------ASEAA 390

Query: 466 GGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKV 525
             + PA                     VVVETFPATVNGTVEGGSGAGRLDLPPGFMFKV
Sbjct: 391 SSSLPA---------------------VVVETFPATVNGTVEGGSGAGRLDLPPGFMFKV 429

Query: 526 QAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFP 585
           QAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFP
Sbjct: 430 QAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFP 489

Query: 586 ENFTERVP 593
           ENFTERVP
Sbjct: 490 ENFTERVP 497


>gi|21536413 bridging integrator 1 isoform 7 [Homo sapiens]
          Length = 475

 Score =  819 bits (2116), Expect = 0.0
 Identities = 444/593 (74%), Positives = 451/593 (76%), Gaps = 118/593 (19%)

Query: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60
           MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR
Sbjct: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60

Query: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120
           LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD
Sbjct: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120

Query: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKPVSLLEK 180
           QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAK       
Sbjct: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAK------- 173

Query: 181 AAPQWCQGKLQAHLVAQTNLLRNQAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN 240
                                   AEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN
Sbjct: 174 ------------------------AEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN 209

Query: 241 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP 300
           TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQ              P 
Sbjct: 210 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQ--------------PS 255

Query: 301 DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPPPKHTPSKEVKQEQILS 360
           D +PA                               KG   P PP  +P+          
Sbjct: 256 DNAPA-------------------------------KGNKSPSPPDGSPAA--------- 275

Query: 361 LFEDTFVPEISVTTPSQFEAPGPFSEQASLLDLDFDPLPPVTSPVKAPTPSGQSIPWDLW 420
                  PEI V    +                          P    TP G ++P    
Sbjct: 276 ------TPEIRVNHEPE--------------------------PAGGATP-GATLPKSPS 302

Query: 421 EPTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGET 480
           +PTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGET
Sbjct: 303 QPTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGET 362

Query: 481 AASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQ 540
           AASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQ
Sbjct: 363 AASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQ 422

Query: 541 LKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERVP 593
           LKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERVP
Sbjct: 423 LKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERVP 475


>gi|21536415 bridging integrator 1 isoform 9 [Homo sapiens]
          Length = 439

 Score =  595 bits (1533), Expect = e-170
 Identities = 310/382 (81%), Positives = 318/382 (83%), Gaps = 40/382 (10%)

Query: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60
           MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR
Sbjct: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60

Query: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120
           LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD
Sbjct: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120

Query: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKPVSLLEK 180
           QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAK       
Sbjct: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAK------- 173

Query: 181 AAPQWCQGKLQAHLVAQTNLLRNQAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN 240
                                   AEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN
Sbjct: 174 ------------------------AEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN 209

Query: 241 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP 300
           TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP
Sbjct: 210 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP 269

Query: 301 DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPV---------PPPPKHTPSK 351
           DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQ  +   V            P  T + 
Sbjct: 270 DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQPAEASEVAGGTQPAAGAQEPGETAAS 329

Query: 352 EVKQEQILSLFEDTFVPEISVT 373
           E     + ++  +TF   ++ T
Sbjct: 330 EAASSSLPAVVVETFPATVNGT 351



 Score =  288 bits (737), Expect = 1e-77
 Identities = 148/175 (84%), Positives = 152/175 (86%), Gaps = 7/175 (4%)

Query: 422 PTESPAGSLP---SGEPSAAEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPG 478
           P  SPA +     + EP  A G    + P  T    P+QPAEASEVAGGTQPAAGAQEPG
Sbjct: 269 PDGSPAATPEIRVNHEPEPAGG----ATPGATLPKSPSQPAEASEVAGGTQPAAGAQEPG 324

Query: 479 ETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDE 538
           ETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDE
Sbjct: 325 ETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDE 384

Query: 539 LQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERVP 593
           LQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERVP
Sbjct: 385 LQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERVP 439


>gi|21536417 bridging integrator 1 isoform 10 [Homo sapiens]
          Length = 409

 Score =  593 bits (1530), Expect = e-169
 Identities = 303/334 (90%), Positives = 303/334 (90%), Gaps = 31/334 (9%)

Query: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60
           MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR
Sbjct: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60

Query: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120
           LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD
Sbjct: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120

Query: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKPVSLLEK 180
           QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAK       
Sbjct: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAK------- 173

Query: 181 AAPQWCQGKLQAHLVAQTNLLRNQAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN 240
                                   AEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN
Sbjct: 174 ------------------------AEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN 209

Query: 241 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP 300
           TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP
Sbjct: 210 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP 269

Query: 301 DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQ 334
           DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQ
Sbjct: 270 DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQ 303



 Score =  236 bits (602), Expect = 4e-62
 Identities = 116/147 (78%), Positives = 122/147 (82%), Gaps = 1/147 (0%)

Query: 448 SQTAEPGPAQPAEASEVAGGTQPA-AGAQEPGETAASEAASSSLPAVVVETFPATVNGTV 506
           +++  P    PA   E+    +P  AG   PG T     + SSLPAVVVETFPATVNGTV
Sbjct: 263 NKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQSSLPAVVVETFPATVNGTV 322

Query: 507 EGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGV 566
           EGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGV
Sbjct: 323 EGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGV 382

Query: 567 KESDWNQHKELEKCRGVFPENFTERVP 593
           KESDWNQHKELEKCRGVFPENFTERVP
Sbjct: 383 KESDWNQHKELEKCRGVFPENFTERVP 409


>gi|4757748 bridging integrator 1 isoform 8 [Homo sapiens]
          Length = 454

 Score =  585 bits (1507), Expect = e-167
 Identities = 310/397 (78%), Positives = 318/397 (80%), Gaps = 55/397 (13%)

Query: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60
           MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR
Sbjct: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60

Query: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120
           LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD
Sbjct: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120

Query: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKPVSLLEK 180
           QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAK       
Sbjct: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAK------- 173

Query: 181 AAPQWCQGKLQAHLVAQTNLLRNQAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN 240
                                   AEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN
Sbjct: 174 ------------------------AEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN 209

Query: 241 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQP--------------- 285
           TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQP               
Sbjct: 210 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPRKKSKLFSRLRRKKN 269

Query: 286 SDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPV---- 341
           SDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQ  +   V    
Sbjct: 270 SDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQPAEASEVAGGT 329

Query: 342 -----PPPPKHTPSKEVKQEQILSLFEDTFVPEISVT 373
                   P  T + E     + ++  +TF   ++ T
Sbjct: 330 QPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGT 366



 Score =  288 bits (737), Expect = 1e-77
 Identities = 148/175 (84%), Positives = 152/175 (86%), Gaps = 7/175 (4%)

Query: 422 PTESPAGSLP---SGEPSAAEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPG 478
           P  SPA +     + EP  A G    + P  T    P+QPAEASEVAGGTQPAAGAQEPG
Sbjct: 284 PDGSPAATPEIRVNHEPEPAGG----ATPGATLPKSPSQPAEASEVAGGTQPAAGAQEPG 339

Query: 479 ETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDE 538
           ETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDE
Sbjct: 340 ETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDE 399

Query: 539 LQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERVP 593
           LQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERVP
Sbjct: 400 LQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERVP 454


>gi|4502081 amphiphysin isoform 1 [Homo sapiens]
          Length = 695

 Score =  461 bits (1186), Expect = e-130
 Identities = 274/622 (44%), Positives = 356/622 (57%), Gaps = 72/622 (11%)

Query: 9   VTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTRLQKDLRTY 68
           +  G  A NVQK+L RAQEKVLQKLGKADETKDEQFE+ VQNF +Q  EGTRLQ++LR Y
Sbjct: 4   IKTGIFAKNVQKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGTRLQRELRGY 63

Query: 69  LASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVDQALLTMDT 128
           LA++K M EAS KL E L EVYEPDW GR++   + E  D+LW D+HQKLVD +LLT+DT
Sbjct: 64  LAAIKGMQEASMKLTESLHEVYEPDWYGREDVKMVGEKCDVLWEDFHQKLVDGSLLTLDT 123

Query: 129 YLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKPVSLLEKAAPQWCQG 188
           YLGQFPDIK+RIAKR RKLVDYDSARHH E+LQ++K+KDE++I+K               
Sbjct: 124 YLGQFPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISK--------------- 168

Query: 189 KLQAHLVAQTNLLRNQAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGL 248
                           AEEE  KAQKVFEE NVDLQEELPSLW+ RVGFYVNTF++++ L
Sbjct: 169 ----------------AEEEFQKAQKVFEEFNVDLQEELPSLWSRRVGFYVNTFKNVSSL 212

Query: 249 EENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP-DGSPAAT 307
           E  FHKE++ L   L +V+  L  QH    FT++  PSD+ P +  K+PSPP + SP  +
Sbjct: 213 EAKFHKEIAVLCHKLYEVMTKLGDQHADKAFTIQGAPSDSGPLRIAKTPSPPEEPSPLPS 272

Query: 308 PEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPPPKHTPSKEVKQEQILSLFEDTFV 367
           P    NH   P   A+P    P+SPSQ RKGPPVPP PK TP+KE++QE I+S FED FV
Sbjct: 273 PTASPNHTLAP---ASPAPARPRSPSQTRKGPPVPPLPKVTPTKELQQENIISFFEDNFV 329

Query: 368 PEISVTTPSQFEAPGPFSEQASLLDLDFDPLPPVTSPVKAP----TPSGQSIPWDLW--- 420
           PEISVTTPSQ E P    ++ +LLDLDFDP  P  +P  +     +P  Q++PWDLW   
Sbjct: 330 PEISVTTPSQNEVP-EVKKEETLLDLDFDPFKPEVTPAGSAGVTHSPMSQTLPWDLWTTS 388

Query: 421 -EPTESPAGSLPSGEPSAAEGTFAVSWPSQT-------AEPGPAQPAEASEVAGGTQPAA 472
            +  +  +G   +G     + +       Q+       +E  P    +A E      PA 
Sbjct: 389 TDLVQPASGGSFNGFTQPQDTSLFTMQTDQSMICNLAESEQAPPTEPKAEEPLAAVTPAV 448

Query: 473 GAQEPGETAASEAASSS--LPAVVVETFPATVNGTVEGGSG----AGRLDLPPGFMFKVQ 526
           G     +T A E    +  +P    +    T+    EG  G    A +  +P G    ++
Sbjct: 449 GLDLGMDTRAEEPVEEAVIIPGADADAAVGTLVSAAEGAPGEEAEAEKATVPAGEGVSLE 508

Query: 527 AQHDYTAT---------DTDEL-----QLKAGDVVLVIPFQNPEEQDEGWL-MGVKESDW 571
                T T         + +EL     Q K    V++ P  N EE+ E  + +G +  + 
Sbjct: 509 EAKIGTETTEGAESAQPEAEELEATVPQEKVIPSVVIEPASNHEEEGENEITIGAEPKET 568

Query: 572 NQHKELEKCRGVFPENFTERVP 593
            +           PE  TE+ P
Sbjct: 569 TEDAAPPGPTSETPELATEQKP 590



 Score =  114 bits (284), Expect = 3e-25
 Identities = 71/203 (34%), Positives = 99/203 (48%), Gaps = 20/203 (9%)

Query: 406 KAPTPSGQSIPWDL----WEPTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEA 461
           KA  P+G+ +  +      E TE    + P  E   A        PS   EP      E 
Sbjct: 496 KATVPAGEGVSLEEAKIGTETTEGAESAQPEAEELEATVPQEKVIPSVVIEPASNHEEEG 555

Query: 462 -SEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLD---- 516
            +E+  G +P    +E  E AA    +S  P +  E  P             G  D    
Sbjct: 556 ENEITIGAEP----KETTEDAAPPGPTSETPELATEQKPIQDPQPTPSAPAMGAADQLAS 611

Query: 517 -------LPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKES 569
                  LPPGF++KV+  HD+ A ++DEL L+ GDVVLV+P  +  +QD GWL+GVKES
Sbjct: 612 AREASQELPPGFLYKVETLHDFEAANSDELTLQRGDVVLVVPSDSEADQDAGWLVGVKES 671

Query: 570 DWNQHKELEKCRGVFPENFTERV 592
           DW Q+++L   +G+FPENFT R+
Sbjct: 672 DWLQYRDLATYKGLFPENFTRRL 694


>gi|21536423 amphiphysin isoform 2 [Homo sapiens]
          Length = 653

 Score =  461 bits (1185), Expect = e-129
 Identities = 272/595 (45%), Positives = 350/595 (58%), Gaps = 60/595 (10%)

Query: 9   VTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTRLQKDLRTY 68
           +  G  A NVQK+L RAQEKVLQKLGKADETKDEQFE+ VQNF +Q  EGTRLQ++LR Y
Sbjct: 4   IKTGIFAKNVQKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGTRLQRELRGY 63

Query: 69  LASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVDQALLTMDT 128
           LA++K M EAS KL E L EVYEPDW GR++   + E  D+LW D+HQKLVD +LLT+DT
Sbjct: 64  LAAIKGMQEASMKLTESLHEVYEPDWYGREDVKMVGEKCDVLWEDFHQKLVDGSLLTLDT 123

Query: 129 YLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKPVSLLEKAAPQWCQG 188
           YLGQFPDIK+RIAKR RKLVDYDSARHH E+LQ++K+KDE++I+K               
Sbjct: 124 YLGQFPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISK--------------- 168

Query: 189 KLQAHLVAQTNLLRNQAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGL 248
                           AEEE  KAQKVFEE NVDLQEELPSLW+ RVGFYVNTF++++ L
Sbjct: 169 ----------------AEEEFQKAQKVFEEFNVDLQEELPSLWSRRVGFYVNTFKNVSSL 212

Query: 249 EENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP-DGSPAAT 307
           E  FHKE++ L   L +V+  L  QH    FT++  PSD+ P +  K+PSPP + SP  +
Sbjct: 213 EAKFHKEIAVLCHKLYEVMTKLGDQHADKAFTIQGAPSDSGPLRIAKTPSPPEEPSPLPS 272

Query: 308 PEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPPPKHTPSKEVKQEQILSLFEDTFV 367
           P    NH   P   A+P    P+SPSQ RKGPPVPP PK TP+KE++QE I+S FED FV
Sbjct: 273 PTASPNHTLAP---ASPAPARPRSPSQTRKGPPVPPLPKVTPTKELQQENIISFFEDNFV 329

Query: 368 PEISVTTPSQFEAPGPFSEQASLLDLDFDPLPPVTSPVKAP----TPSGQSIPWDLW--- 420
           PEISVTTPSQ E P    ++ +LLDLDFDP  P  +P  +     +P  Q++PWDLW   
Sbjct: 330 PEISVTTPSQNEVP-EVKKEETLLDLDFDPFKPEVTPAGSAGVTHSPMSQTLPWDLWTTS 388

Query: 421 -EPTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGE 479
            +  +  +G   +G     + +       Q+       P   ++ A GT  +A    PGE
Sbjct: 389 TDLVQPASGGSFNGFTQPQDTSLFTMQTDQSMICNLIIPGADADAAVGTLVSAAEGAPGE 448

Query: 480 TAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDEL 539
            A  EA  +++PA    +      GT E   GA              AQ +    +    
Sbjct: 449 EA--EAEKATVPAGEGVSLEEAKIGT-ETTEGA------------ESAQPEAEELEATVP 493

Query: 540 QLKAGDVVLVIPFQNPEEQDEGWL-MGVKESDWNQHKELEKCRGVFPENFTERVP 593
           Q K    V++ P  N EE+ E  + +G +  +  +           PE  TE+ P
Sbjct: 494 QEKVIPSVVIEPASNHEEEGENEITIGAEPKETTEDAAPPGPTSETPELATEQKP 548



 Score =  114 bits (284), Expect = 3e-25
 Identities = 71/203 (34%), Positives = 99/203 (48%), Gaps = 20/203 (9%)

Query: 406 KAPTPSGQSIPWDL----WEPTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEA 461
           KA  P+G+ +  +      E TE    + P  E   A        PS   EP      E 
Sbjct: 454 KATVPAGEGVSLEEAKIGTETTEGAESAQPEAEELEATVPQEKVIPSVVIEPASNHEEEG 513

Query: 462 -SEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLD---- 516
            +E+  G +P    +E  E AA    +S  P +  E  P             G  D    
Sbjct: 514 ENEITIGAEP----KETTEDAAPPGPTSETPELATEQKPIQDPQPTPSAPAMGAADQLAS 569

Query: 517 -------LPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKES 569
                  LPPGF++KV+  HD+ A ++DEL L+ GDVVLV+P  +  +QD GWL+GVKES
Sbjct: 570 AREASQELPPGFLYKVETLHDFEAANSDELTLQRGDVVLVVPSDSEADQDAGWLVGVKES 629

Query: 570 DWNQHKELEKCRGVFPENFTERV 592
           DW Q+++L   +G+FPENFT R+
Sbjct: 630 DWLQYRDLATYKGLFPENFTRRL 652


>gi|49472835 bridging integrator 2 [Homo sapiens]
          Length = 565

 Score =  313 bits (801), Expect = 4e-85
 Identities = 199/502 (39%), Positives = 275/502 (54%), Gaps = 77/502 (15%)

Query: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60
           MAE G  G  AG  A  VQKK +RAQEKVLQKLGKA ETKDE+FEQ   NF +Q  EG +
Sbjct: 1   MAE-GKAGGAAGLFAKQVQKKFSRAQEKVLQKLGKAVETKDERFEQSASNFYQQQAEGHK 59

Query: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120
           L KDL+ +L++VK MHE+SK+++E LQE+Y  +W G +E   I  NNDLLW DY +KL D
Sbjct: 60  LYKDLKNFLSAVKVMHESSKRVSETLQEIYSSEWDGHEELKAIVWNNDLLWEDYEEKLAD 119

Query: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKPVSLLEK 180
           QA+ TM+ Y+ QF +IK RIAKRGRKLVDYDSARHH E++Q AKKKDEAK AK       
Sbjct: 120 QAVRTMEIYVAQFSEIKERIAKRGRKLVDYDSARHHLEAVQNAKKKDEAKTAK------- 172

Query: 181 AAPQWCQGKLQAHLVAQTNLLRNQAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN 240
                                   AEEE  KAQ VFE++N +L EELP L+NSR+G YV 
Sbjct: 173 ------------------------AEEEFNKAQTVFEDLNQELLEELPILYNSRIGCYVT 208

Query: 241 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDN------APAKGN 294
            FQ+I+ L + F++EMSKLN NL +V+  LEKQH +  F VK   S +      +P    
Sbjct: 209 IFQNISNLRDVFYREMSKLNHNLYEVMSKLEKQHSNKVFVVKGLSSSSRRSLVISPPVRT 268

Query: 295 KSPSPPDGSPAATPEIRVNHEPEPAGGA---TPGATLPKSPSQLRKGPPVPPPPKHTPSK 351
            + S P  SP +   + +  E E         P A   +  S+++         +    +
Sbjct: 269 ATVSSPLTSPTSPSTLSLKSESESVSATEDLAPDAAQGEDNSEIK---------ELLEEE 319

Query: 352 EVKQEQILSLFEDTFVPEISVTTPSQFEAPGPFSEQASLLDLDFDPLPPVTSPVKAPTPS 411
           E+++E   +   +   P  +   P+Q + P P +E+A   +   + LP  T+P       
Sbjct: 320 EIEKEGSEASSSEEDEPLPACNGPAQAQ-PSPTTERAKSQE---EVLPSSTTP------- 368

Query: 412 GQSIPWDLWEPTESPAGSL-PSGEPSAAEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQP 470
                        SP G+L PSG+PS++     V   ++TA  G  QP + + +   + P
Sbjct: 369 -------------SPGGALSPSGQPSSS--ATEVVLRTRTASEGSEQPKKRASIQRTSAP 413

Query: 471 AAGAQEPGETAASEAASSSLPA 492
            +    P  TA+   +S ++P+
Sbjct: 414 PSRPPPPRATASPRPSSGNIPS 435


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 61.2 bits (147), Expect = 3e-09
 Identities = 64/218 (29%), Positives = 83/218 (38%), Gaps = 38/218 (17%)

Query: 285  PSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPP 344
            P   AP     +P  P G PA +P         P G  TP A  P SP    KG P  PP
Sbjct: 1282 PHKGAPNPAVVTPPSPKGGPATSP---------PKGAPTPPAATPPSP----KGSPGTPP 1328

Query: 345  PKHTPSKEVKQEQILSLFEDTFVPEISVTTPSQFEAP-GPFSEQASLLDLDFDPLPPVTS 403
            PK  P+        ++       P +  TTPS    P  P S++         P PP  +
Sbjct: 1329 PKGAPTPPA-----VTPPSPKGTPTLPATTPSSKGGPTTPSSKEG--------PTPPAAT 1375

Query: 404  P-------VKAPTPS-GQSIPWDLWEPTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGP 455
            P       +  P+P  G +IP    +PT SPA  +P   P  A  T      + T   G 
Sbjct: 1376 PSHKGGPAMTPPSPKRGPAIPSPKGDPT-SPA-VIPL-SPKKAPATPVTREGAATPSKGD 1432

Query: 456  AQPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAV 493
              P   + V+    PA  A + G    S     +LPAV
Sbjct: 1433 LTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAV 1470



 Score = 54.3 bits (129), Expect = 3e-07
 Identities = 57/220 (25%), Positives = 76/220 (34%), Gaps = 25/220 (11%)

Query: 285  PSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPP 344
            P   AP     +P  P GSP           P P G  TP A  P SP      P   P 
Sbjct: 1305 PPKGAPTPPAATPPSPKGSPGT---------PPPKGAPTPPAVTPPSPKGTPTLPATTPS 1355

Query: 345  PKHTP-SKEVKQEQILSLFEDTFVPEISVTTPSQFEAPGPFSEQASLLDLDFDPLPPVTS 403
             K  P +   K+         +     ++T PS    P   S +         PL P  +
Sbjct: 1356 SKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKA 1415

Query: 404  PVKAPTPSGQSIP--WDLWEPT-------ESPAGSLPSGEPSAAEGTFAVSWPSQTAEPG 454
            P    T  G + P   DL  P        ++PA S P G P+        + P+ T  P 
Sbjct: 1416 PATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVT-PPS 1474

Query: 455  PAQPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVV 494
            P +P    +VA  + P      P    A      +LPAV+
Sbjct: 1475 PKEPPAPKQVATSSSPKKAPATPAPMGA-----PTLPAVI 1509



 Score = 53.5 bits (127), Expect = 5e-07
 Identities = 66/222 (29%), Positives = 78/222 (35%), Gaps = 27/222 (12%)

Query: 289  APAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPPPKHT 348
            APA    S SP        P+  +   P P G  TP A  P SP    KG P  P PK  
Sbjct: 908  APALSMTSSSPKKARATPAPK-GIPASPSPKGAPTPPAATPPSP----KGGPATPSPKWA 962

Query: 349  PSKEVKQEQILSLFEDTFVPE-----ISVTTPSQFEAPGPFSEQASLLDLDFDPLPPVTS 403
            P+              T  P+      + T PS    P   S + +       P  P  S
Sbjct: 963  PTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGS 1022

Query: 404  PVKAPTPSGQSIPWDLWEPTESPAGS-----LPSGEPSAAEGTFAVSWPSQTAEPGPAQP 458
            P   P P G S P     P  SP GS     LP G P+    T A + PS   + GPA P
Sbjct: 1023 PAATPFPKGASTPPAATPP--SPKGSPAATPLPKGAPT----TPAATLPS--PKGGPATP 1074

Query: 459  AEASEVAGGTQPAAGAQEP-GETAASEAASSSLPAVVVETFP 499
               S     T PAA    P G  A      + +P       P
Sbjct: 1075 ---SLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSP 1113



 Score = 53.5 bits (127), Expect = 5e-07
 Identities = 68/269 (25%), Positives = 100/269 (37%), Gaps = 61/269 (22%)

Query: 280  TVKAQPSDNAPAKGNKSPS------------PPDGSPAATPEIRVNHEPE-------PAG 320
            ++K  P+ +AP  G  +PS            P    P A  ++  +  P+       P G
Sbjct: 1442 SLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMG 1501

Query: 321  GATPGATLPKSPSQLRKGP-----PVPPP----PKHTPSKEVKQEQILSLFEDTFVPEIS 371
              T  A +P SP ++   P     P+ P      K TP+    +E ++        P+ +
Sbjct: 1502 APTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKT 1561

Query: 372  VTTPSQFEAPG-PFSEQASL---------------LDLDFDPLPPVTSPVKAPTPSGQSI 415
               P+  EAP  P S++AS                 +L   P     SP +APTP   + 
Sbjct: 1562 PAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTP 1621

Query: 416  PWDLWEPTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQ 475
            P     P + PA   P G P++   T     PS + +  P  PA  +   G T P A   
Sbjct: 1622 P----SPEKGPATPAPKGTPTSPPVT-----PS-SLKDSPTSPASVTCKMGATVPQASKG 1671

Query: 476  EP---GETAASEA----ASSSLPAVVVET 497
             P   G TA  E     A  S P +   T
Sbjct: 1672 LPAKKGPTALKEVLVAPAPESTPIITAPT 1700



 Score = 53.1 bits (126), Expect = 7e-07
 Identities = 64/233 (27%), Positives = 87/233 (37%), Gaps = 31/233 (13%)

Query: 283  AQPSDN-APAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPV 341
            A PS   AP     +P  P GSPAATP         P G +TP A  P SP       P+
Sbjct: 1001 ATPSPKGAPTPPAVTPPSPKGSPAATPF--------PKGASTPPAATPPSPKGSPAATPL 1052

Query: 342  PPPPKHTPSKEV---KQEQILSLFEDTFVPEISVTTPSQFEAPGPFSEQASLLDLDFDPL 398
            P     TP+  +   K        +    P  + T PS    P   S + +       P+
Sbjct: 1053 PKGAPTTPAATLPSPKGGPATPSLKGAPTPP-AATPPSPKGGPATPSPKGA-------PM 1104

Query: 399  PPVTSPVKAPTPSGQSIPWDLWEPTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQP 458
            PP  +P   P+P G      L  P    A + P+  P + +G  A   P + A   PA  
Sbjct: 1105 PPAATP---PSPKG-----GLATPPHKGAPTTPAATPPSPKGGLATP-PPKGAPTTPAAT 1155

Query: 459  AEASEVAGGTQPAAGA-QEPGETAASEAASSSLPAVV-VETFPATVNGTVEGG 509
              + +    T P  GA   P  T  S     + P+     T PA    + +GG
Sbjct: 1156 PPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGG 1208



 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 63/215 (29%), Positives = 79/215 (36%), Gaps = 41/215 (19%)

Query: 285  PSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPP 344
            P ++   +G+K       SP  TP       P P G  TP A  P SP    KG  V  P
Sbjct: 837  PENSLSFQGSKDSPATTHSP--TP-------PSPKGAPTPSAVTPLSP----KG--VTLP 881

Query: 345  PKHTPSKEVKQEQILSLFEDTFVPEISVTTPSQFEAPGPFSEQASLLDLDFDP----LPP 400
            PK TP+  V              P+    TP+  +AP      +S       P    +P 
Sbjct: 882  PKETPTPSVVNLPF---------PKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPA 932

Query: 401  VTSPVKAPTP---------SGQSIPWDLWEPTESPAGSLPS--GEPSAAEGTFAVSWPSQ 449
              SP  APTP          G + P   W PT  PA + PS  G P+      A + P+ 
Sbjct: 933  SPSPKGAPTPPAATPPSPKGGPATPSPKWAPT-PPAATPPSPKGGPATPSPKGAPTPPAA 991

Query: 450  TAEPGPAQPAEASEVAGGTQPAAGAQEP-GETAAS 483
            T       PA  S     T PA     P G  AA+
Sbjct: 992  TPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAAT 1026



 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 68/240 (28%), Positives = 83/240 (34%), Gaps = 27/240 (11%)

Query: 275  GSNTFTVKAQPSDNA-----PAKGNKSPSPPDGS--PAATPEIRVNHEPEPAGG-ATP-- 324
            G  T ++K  P+  A     P  G  +PSP      PAATP       P P GG ATP  
Sbjct: 1070 GPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATP-------PSPKGGLATPPH 1122

Query: 325  --GATLPKSPSQLRKGPPVPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPSQFEAPG 382
                T P +     KG    PPPK  P+              T  P+ + TTP+    P 
Sbjct: 1123 KGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAA-TPPS 1181

Query: 383  PFSEQASLLDLDFDPLPPVTSPVKA---PTPSGQSIPWDLWEPTESPAGSLPSGEPSAAE 439
            P    A+         P  T P       TPS +  P        SP G L +  P  A 
Sbjct: 1182 PKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAP 1241

Query: 440  GTFAVSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFP 499
             T A + PS    P    P  A      T P+      G  A      +  PAVV    P
Sbjct: 1242 TTPAATPPSPKGGPATPPPKGAPTPPAATPPSL----KGGLATPPHKGAPNPAVVTPPSP 1297



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 62/236 (26%), Positives = 80/236 (33%), Gaps = 17/236 (7%)

Query: 285  PSDNAPA-KGNKSPSPPDGSP---AATPEIRVNH--EPEPAGGATPGATLPKSPSQLRKG 338
            P+   P+ KG  +  PP G+P   AATP         P P G  T  A  P SP    KG
Sbjct: 1152 PAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSP----KG 1207

Query: 339  PPVPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPSQFEAPGPFSEQASLLDLDFDPL 398
                P PK  P+              T  P+ + TTP+    P P    A+       P 
Sbjct: 1208 GLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAA-TPPSPKGGPATPPPKGA-PT 1265

Query: 399  PPVTSPVKAP----TPSGQSIPWDLWEPTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPG 454
            PP  +P        TP  +  P        SP G   +  P  A    A + PS    PG
Sbjct: 1266 PPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPG 1325

Query: 455  PAQPAEASEVAGGTQPA-AGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGG 509
               P  A      T P+  G      T  S     + P+      P     + +GG
Sbjct: 1326 TPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGG 1381



 Score = 31.2 bits (69), Expect = 2.8
 Identities = 56/240 (23%), Positives = 81/240 (33%), Gaps = 31/240 (12%)

Query: 275 GSNTFTVKAQPS-DNAPAKGNKSPSPPDGSPAATPEIRVNHE-----PEPAGGATPGATL 328
           G++T+T  A P  +   +   K+    +G+    P +    E     P P     P ATL
Sbjct: 665 GTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATL 724

Query: 329 PKSPSQLRKGPPVPPPPKHTPSKEVKQEQI---LSLFEDTFVPEISVTTPSQFEAPGPFS 385
             +P   +  P    PP  TP    K + I    +L      P+   T  S   A     
Sbjct: 725 VLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSK 784

Query: 386 EQASLLDLDFDPLPPVTSP--VKAPTPSGQSIPWDLWEPTESPAGSLPSGEPSAAEGTF- 442
              + L     PL    SP   + PT  G + P       ++P G+L S   S  E +F 
Sbjct: 785 GTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGP-------DTPIGNL-SSPVSPVEASFL 836

Query: 443 ---------AVSWPSQTAEPGPAQPAEASEVAGGT--QPAAGAQEPGETAASEAASSSLP 491
                    +   P+ T  P P  P  A   +  T   P      P ET      +   P
Sbjct: 837 PENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFP 896


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 59.3 bits (142), Expect = 1e-08
 Identities = 64/235 (27%), Positives = 86/235 (36%), Gaps = 34/235 (14%)

Query: 283 AQPSDNAPAKGNKSPSPPDGSPA------ATPEIRVNHEPEPAGGATPGATLPKS----- 331
           A PS +AP      PSPP   P+       +P ++  H   P+   +P AT P       
Sbjct: 341 APPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPAL 400

Query: 332 ---PSQLRKGPPVPPP--PKHTPSKEVKQEQILSLFEDTFVPEISVTTPSQFEAPG--PF 384
              P Q    PP  PP  P  TPS +      + L +  F P  S    + F  P   P 
Sbjct: 401 ALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPV 460

Query: 385 SEQASLLDLDFDPLPPVTSPVKAPTPSGQSIPWDLWEPTESPAGSLPSGEPSAAEGTFAV 444
           S  A+         PP  +P     P  Q  P     P  SP+ + P   P         
Sbjct: 461 SPSAT---------PPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP--- 508

Query: 445 SWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFP 499
             P Q A+P P  P   +       P+  A  PG+  A  + S+SLP   + T P
Sbjct: 509 --PLQLAKPPPQAPPALATPPLQALPSPPASFPGQ--APFSPSASLPMSPLATPP 559



 Score = 50.1 bits (118), Expect = 6e-06
 Identities = 69/272 (25%), Positives = 92/272 (33%), Gaps = 37/272 (13%)

Query: 281 VKAQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEP---EPAGGATPGATLPKSPSQLRK 337
           V   P  + P   + +P P    P A P +++   P    PA    P   LP  P+    
Sbjct: 481 VPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPG 540

Query: 338 GPP------VPPPPKHTPSKEVKQEQILSLFEDTFVPEISVT--TPSQFEAPGP-FSEQA 388
             P      +P  P  TP  +        L +    P  S T   P +   PGP  S   
Sbjct: 541 QAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSG 600

Query: 389 SLLDLDFDPLPPVTSPVKAP------------TPSGQSIPWDLWEPTESPAGSLPSGEPS 436
             L L   P PP   P ++P            + S  S P +L      P G   +  P 
Sbjct: 601 PRLTLALAPGPP-PPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPP 659

Query: 437 AAEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPG---------ETAASEAAS 487
            AE   A   P+  +  GPA P       G   P   A  PG         ET   E+A+
Sbjct: 660 DAE--LAACHPAAWSR-GPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESAT 716

Query: 488 SSLPAVVVETFPATVNGTVEGGSGAGRLDLPP 519
            +  A+     P T  G    G+GAG     P
Sbjct: 717 PAPGALDPGPSPGTSGGKAAAGAGAGASSRSP 748



 Score = 40.8 bits (94), Expect = 0.004
 Identities = 61/237 (25%), Positives = 86/237 (36%), Gaps = 43/237 (18%)

Query: 299 PPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPPPKHTPSKEVKQEQI 358
           PP  SP A+P ++    P P  G     + P+    L  GPP  PPP  +PS  +    +
Sbjct: 574 PP--SPPASPTLQAPRRP-PTPGPDTSVSGPRLTLALAPGPP--PPPSRSPSSTLSGPDL 628

Query: 359 LSLFED-TFVPEISVTTPSQFE-----APGPFSEQASLLDLDFD--PLPPVTSPVKAPTP 410
                  T  PE      S  E     +P P +E A+     +   P PP+     AP  
Sbjct: 629 AGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFR-GAP-- 685

Query: 411 SGQSIPWDLWEPTESPAGSLPSGEPSAAEGTFAV----SWPSQTAEPGPAQPAEASEVAG 466
            G  +PW             P+  P +A+G   +       S T  PG   P  +   +G
Sbjct: 686 -GAPLPWP------------PATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSG 732

Query: 467 GTQPA-----AGAQEPGETAASEAASSSLPAVVVE-----TFPATVNGTVEGGSGAG 513
           G   A     A ++ P +    E    +L A VV+     T          GGSG G
Sbjct: 733 GKAAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAEGAAGGSGGG 789



 Score = 36.2 bits (82), Expect = 0.087
 Identities = 55/223 (24%), Positives = 80/223 (35%), Gaps = 22/223 (9%)

Query: 287 DNAPAKGNKSPSP---PDGSPAATPEIRVNHEPEPAGG------ATPGATLPKSPSQLRK 337
           D APA G  S SP   P  S A   +        P         ATP    P SPS    
Sbjct: 291 DAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPS 350

Query: 338 GPPVPPPPKHTPSKEVKQEQILSL-FEDTFVPEISVTTPSQFEAPGPFSEQA-SLLDLDF 395
              +P PP   PS+        +L    +F+P   +   S    P P +  A +L  L  
Sbjct: 351 LQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPL---SPLATPPPQAPPALALPPLQA 407

Query: 396 DPLPPVT---SPVKAPTPSGQS-----IPWDLWEPTESPAGSLPSGEPSAAEGTFAVSWP 447
            P PP +   SP+  P+P   +     +    + P  SP    P   P++   + + + P
Sbjct: 408 PPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPP 467

Query: 448 SQTAEPGPAQPAEASEVAGGTQPAAGAQEPGETAASEAASSSL 490
           SQ      A P +       + P + +  P   A    A+  L
Sbjct: 468 SQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPL 510


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 59.3 bits (142), Expect = 1e-08
 Identities = 64/235 (27%), Positives = 86/235 (36%), Gaps = 34/235 (14%)

Query: 283 AQPSDNAPAKGNKSPSPPDGSPA------ATPEIRVNHEPEPAGGATPGATLPKS----- 331
           A PS +AP      PSPP   P+       +P ++  H   P+   +P AT P       
Sbjct: 302 APPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPAL 361

Query: 332 ---PSQLRKGPPVPPP--PKHTPSKEVKQEQILSLFEDTFVPEISVTTPSQFEAPG--PF 384
              P Q    PP  PP  P  TPS +      + L +  F P  S    + F  P   P 
Sbjct: 362 ALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPV 421

Query: 385 SEQASLLDLDFDPLPPVTSPVKAPTPSGQSIPWDLWEPTESPAGSLPSGEPSAAEGTFAV 444
           S  A+         PP  +P     P  Q  P     P  SP+ + P   P         
Sbjct: 422 SPSAT---------PPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP--- 469

Query: 445 SWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFP 499
             P Q A+P P  P   +       P+  A  PG+  A  + S+SLP   + T P
Sbjct: 470 --PLQLAKPPPQAPPALATPPLQALPSPPASFPGQ--APFSPSASLPMSPLATPP 520



 Score = 50.1 bits (118), Expect = 6e-06
 Identities = 69/272 (25%), Positives = 92/272 (33%), Gaps = 37/272 (13%)

Query: 281 VKAQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEP---EPAGGATPGATLPKSPSQLRK 337
           V   P  + P   + +P P    P A P +++   P    PA    P   LP  P+    
Sbjct: 442 VPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPG 501

Query: 338 GPP------VPPPPKHTPSKEVKQEQILSLFEDTFVPEISVT--TPSQFEAPGP-FSEQA 388
             P      +P  P  TP  +        L +    P  S T   P +   PGP  S   
Sbjct: 502 QAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSG 561

Query: 389 SLLDLDFDPLPPVTSPVKAP------------TPSGQSIPWDLWEPTESPAGSLPSGEPS 436
             L L   P PP   P ++P            + S  S P +L      P G   +  P 
Sbjct: 562 PRLTLALAPGPP-PPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPP 620

Query: 437 AAEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPG---------ETAASEAAS 487
            AE   A   P+  +  GPA P       G   P   A  PG         ET   E+A+
Sbjct: 621 DAE--LAACHPAAWSR-GPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESAT 677

Query: 488 SSLPAVVVETFPATVNGTVEGGSGAGRLDLPP 519
            +  A+     P T  G    G+GAG     P
Sbjct: 678 PAPGALDPGPSPGTSGGKAAAGAGAGASSRSP 709



 Score = 40.8 bits (94), Expect = 0.004
 Identities = 61/237 (25%), Positives = 86/237 (36%), Gaps = 43/237 (18%)

Query: 299 PPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPPPKHTPSKEVKQEQI 358
           PP  SP A+P ++    P P  G     + P+    L  GPP  PPP  +PS  +    +
Sbjct: 535 PP--SPPASPTLQAPRRP-PTPGPDTSVSGPRLTLALAPGPP--PPPSRSPSSTLSGPDL 589

Query: 359 LSLFED-TFVPEISVTTPSQFE-----APGPFSEQASLLDLDFD--PLPPVTSPVKAPTP 410
                  T  PE      S  E     +P P +E A+     +   P PP+     AP  
Sbjct: 590 AGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFR-GAP-- 646

Query: 411 SGQSIPWDLWEPTESPAGSLPSGEPSAAEGTFAV----SWPSQTAEPGPAQPAEASEVAG 466
            G  +PW             P+  P +A+G   +       S T  PG   P  +   +G
Sbjct: 647 -GAPLPWP------------PATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSG 693

Query: 467 GTQPA-----AGAQEPGETAASEAASSSLPAVVVE-----TFPATVNGTVEGGSGAG 513
           G   A     A ++ P +    E    +L A VV+     T          GGSG G
Sbjct: 694 GKAAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAEGAAGGSGGG 750



 Score = 39.3 bits (90), Expect = 0.010
 Identities = 53/221 (23%), Positives = 79/221 (35%), Gaps = 20/221 (9%)

Query: 283 AQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPS-----QLRK 337
           A PS   P KG ++  PP  +P              +  ATP  + P SPS     Q   
Sbjct: 258 AHPSQPKP-KGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLP 316

Query: 338 GPPVPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPSQFEAPGPFSEQASLLDLDFDP 397
            PP  PP + T S      Q    F  +  P +S       +AP       +L  L   P
Sbjct: 317 SPPATPPSQATTSLGSPTLQATHSFLPS--PPLSPLATPPPQAP----PALALPPLQAPP 370

Query: 398 LPPVT---SPVKAPTPSGQS-----IPWDLWEPTESPAGSLPSGEPSAAEGTFAVSWPSQ 449
            PP +   SP+  P+P   +     +    + P  SP    P   P++   + + + PSQ
Sbjct: 371 SPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQ 430

Query: 450 TAEPGPAQPAEASEVAGGTQPAAGAQEPGETAASEAASSSL 490
                 A P +       + P + +  P   A    A+  L
Sbjct: 431 APPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPL 471



 Score = 31.2 bits (69), Expect = 2.8
 Identities = 65/259 (25%), Positives = 84/259 (32%), Gaps = 66/259 (25%)

Query: 289 APAKGNKSPSPPDGSPAATPEIR------------VNHEP--EPAGGATPGATLPKS--- 331
           A A G  +P PP GSP   P +             V  +P  E AGG   GAT+P+S   
Sbjct: 19  ARAPGLLTPRPP-GSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIG-GATIPESAPR 76

Query: 332 --PSQLRKGPPVPPPPKHTPSKEVKQEQILS--LFEDTFVP------------EISVTTP 375
             P++  + P      +  P+K      + S      T  P            E +V   
Sbjct: 77  AGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARG 136

Query: 376 SQFEAPGPFSEQASLLDLDFDPLPPVTSPVKA--------------PTPSGQSIPWDLWE 421
              EAP   +  A        P P   SP  A              P PS +  P     
Sbjct: 137 KATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRP----- 191

Query: 422 PTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGETA 481
           PTE P  S+ S    +            T EP PA     S   G  +PA+ +     T 
Sbjct: 192 PTEGPRKSVSSASEHS------------TTEPSPAARRRPSAGGGLQRPASRSLSSSATP 239

Query: 482 ASEAASSSLPAVVVETFPA 500
            S  A S   A      PA
Sbjct: 240 LSSPARSGPSARGTPRAPA 258


>gi|149773456 hypothetical protein LOC643314 [Homo sapiens]
          Length = 1427

 Score = 57.0 bits (136), Expect = 5e-08
 Identities = 66/248 (26%), Positives = 93/248 (37%), Gaps = 34/248 (13%)

Query: 280  TVKAQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGP 339
            TV A    +  A    +P  P    AA P      EP     A P    P SP+     P
Sbjct: 980  TVHAPEEPDTAAVRVSTPEEPASPAAAVP---TPEEPTSPAAAVPTPEEPTSPAAAVPPP 1036

Query: 340  PVPPPPKH---TPSKEVKQEQILSLFEDTFVPEISVTTPSQFEAPG---PFSEQASLLDL 393
              P  P     TP +       +   E+   P  +V TP +  +P    P  E+ +    
Sbjct: 1037 EEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPT---- 1092

Query: 394  DFDPLPPVTSPVKAPTPSGQSIPWDLWEPTESPAGSLPSGEPSAAEGTFAVSWPSQTAEP 453
               P   V +P + PT    ++P    E   SPA ++P+ E  A+    AV  P + A P
Sbjct: 1093 --SPAAAVPTP-EEPTSPAAAVPTP--EEPASPAAAVPTPEEPASPAA-AVPTPEEPAFP 1146

Query: 454  GPAQPAEASEVAG---------GTQPAAGAQEPGETAASEAASSSL-----PAVVVETFP 499
             PA P      +             PAA    P E+A+  A  ++L     PA  V T P
Sbjct: 1147 APAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPT-P 1205

Query: 500  ATVNGTVE 507
            A +  T+E
Sbjct: 1206 AAMVATLE 1213



 Score = 57.0 bits (136), Expect = 5e-08
 Identities = 63/246 (25%), Positives = 91/246 (36%), Gaps = 15/246 (6%)

Query: 266  VLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPG 325
            V V   ++  S    V       +PA    +P  P    AA P      EP     A P 
Sbjct: 992  VRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPP---PEEPTSPAAAVPT 1048

Query: 326  ATLPKSPSQLRKGPPVPPPPKH---TPSKEVKQEQILSLFEDTFVPEISVTTPSQFEAPG 382
               P SP+     P  P  P     TP +       +   E+   P  +V TP +  +P 
Sbjct: 1049 PEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSP- 1107

Query: 383  PFSEQASLLDLDFDPLPPVTSPVKAPTPSGQSIPWDLWEPTESPAGSLPSGEPSAAEGTF 442
                 A+ +    +P  P  +      P+  +      E    PA ++P+ E SA+    
Sbjct: 1108 -----AAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESAS-AAV 1161

Query: 443  AVSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVE-TFPAT 501
            AV  P ++A P  A P  A E A      A  +EP   AAS    +++ A + E T PA 
Sbjct: 1162 AVPTPEESASPAAAVPTPA-ESASFAAVVATLEEPTSPAASVPTPAAMVATLEEFTSPAA 1220

Query: 502  VNGTVE 507
               T E
Sbjct: 1221 SVPTSE 1226



 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 65/238 (27%), Positives = 86/238 (36%), Gaps = 29/238 (12%)

Query: 298  SPPDGSPAATPEIRVNHEPEPAGGATPGATLP-----KSPSQLRKGPPVPPPPKHTPSKE 352
            SP + +PA    I        AG +   A L             +GP  P    H P + 
Sbjct: 928  SPEETAPAVAAAITQEGMSAVAGFSPEWAALAITVPITEEDGTPEGPVTPATTVHAPEEP 987

Query: 353  VKQEQILSLFEDTFVPEISVTTPSQFEAPG---PFSEQASLLDLDFDPLPPVTSPVKA-P 408
                  +S  E+   P  +V TP +  +P    P  E+ +       P    TSP  A P
Sbjct: 988  DTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVP 1047

Query: 409  TPSGQSIPWDL----WEPTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEASEV 464
            TP   + P        EPT SPA ++P+ E   +    AV  P +   P  A P      
Sbjct: 1048 TPEEPTSPAAAVPTPEEPT-SPAAAVPTPEEPTSPAA-AVPTPEEPTSPAAAVPTPEEP- 1104

Query: 465  AGGTQPAAGAQEPGETAASEAA-----SSSLPAVVVET-----FPATVNGTVEGGSGA 512
               T PAA    P E A+  AA       + PA  V T     FPA    T E  + A
Sbjct: 1105 ---TSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASA 1159


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 53.1 bits (126), Expect = 7e-07
 Identities = 64/245 (26%), Positives = 86/245 (35%), Gaps = 28/245 (11%)

Query: 281 VKAQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPP 340
           V   P  + P   + +P P    P A P ++V   P  +   +P AT P     L   PP
Sbjct: 706 VPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPP 765

Query: 341 V---PPPPKHTPSKEVKQEQILSLFEDTFVP-EISVTTPSQFEAPGPFSEQASLLDLDFD 396
           +   P PP   P   + +    +       P +   + P+ F    PFS  ASL      
Sbjct: 766 LQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLA 825

Query: 397 PLPPVTSPVKAPTPSGQSIPWDLWEPTESPAGSLPSGEPSAAEGTFAVSWPSQT--AEPG 454
             PP   PV A  P  Q  P     P  SP    P   P+    T +VS P  T    PG
Sbjct: 826 TPPPQAPPVLA-APLLQVPP----SPPASPTLQAPRRPPTPGPDT-SVSGPRLTLALAPG 879

Query: 455 PAQPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGR 514
           P  P   S       P++    P     S +A+S+         P  + G   G  G   
Sbjct: 880 PPPPPSRS-------PSSTLSGPDLAGHSSSATST---------PEELRGYDSGPEGGAA 923

Query: 515 LDLPP 519
              PP
Sbjct: 924 ASPPP 928



 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 75/293 (25%), Positives = 96/293 (32%), Gaps = 87/293 (29%)

Query: 297  PSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPPPKHTPSKEVKQE 356
            P+ P  SP+ATP  RV     P   A P    P  P+ L   P   PPP+  P+      
Sbjct: 742  PASPPMSPSATPPPRV----PPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPL 797

Query: 357  QILSLFEDTFVPEISVTTPSQFEAPGPFSEQASLLD------------------LDFDPL 398
            Q L             + P+ F    PFS  ASL                    L   P 
Sbjct: 798  QALP------------SPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPS 845

Query: 399  PPVT----SPVKAPTP------SGQSI-----PWDLWEPTESPAGSLPSGEPSAAEGTFA 443
            PP +    +P + PTP      SG  +     P     P+ SP+ +L SG   A   + A
Sbjct: 846  PPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTL-SGPDLAGHSSSA 904

Query: 444  VSWPSQ------------TAEP----------------GPAQPAEASEVAGGTQPAAGAQ 475
             S P +             A P                GPA P       G   P   A 
Sbjct: 905  TSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPAT 964

Query: 476  EPG---------ETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPP 519
             PG         ET   E+A+ +  A+     P T  G    G+GAG     P
Sbjct: 965  GPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSP 1017



 Score = 50.4 bits (119), Expect = 4e-06
 Identities = 66/223 (29%), Positives = 82/223 (36%), Gaps = 32/223 (14%)

Query: 287 DNAPAKGNKSPSPPDGSPAATPE---IRVNHEPEPAGGATP-GATLPKSPSQLRKGPPVP 342
           D APA G     P   SP ATP     +    P P   ATP  ATLP SP      P  P
Sbjct: 291 DAAPALG-----PLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAP 345

Query: 343 PPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPSQFEAPGPFSEQASLLDLDFDPLPPVT 402
           P P   PS +              +P    T PSQ  AP   +            +PP+ 
Sbjct: 346 PSPSAPPSLQT-------------LPSPPATPPSQ--APPSMTTPPMQAPPSLQTIPPIQ 390

Query: 403 SPVKAPTPSGQSIPWDLWEPTESPAGSLPSGEPS-AAEGTFAVSWPSQTAEPGPAQPAEA 461
            P    +PS Q+ P  L   +     SL  G P+  A  +F    P QT     A     
Sbjct: 391 VPHSLTSPSLQAPPSPLALSSLQATTSL--GSPTLQATHSFLTMSPRQT----QASLTSP 444

Query: 462 SEVAGGTQPAAGAQEPGETAASEAASSSL-PAVVVETFPATVN 503
           S  A     +   Q P    AS    +SL PAV   + P T++
Sbjct: 445 SRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIH 487



 Score = 40.8 bits (94), Expect = 0.004
 Identities = 61/237 (25%), Positives = 86/237 (36%), Gaps = 43/237 (18%)

Query: 299  PPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPPPKHTPSKEVKQEQI 358
            PP  SP A+P ++    P P  G     + P+    L  GPP  PPP  +PS  +    +
Sbjct: 843  PP--SPPASPTLQAPRRP-PTPGPDTSVSGPRLTLALAPGPP--PPPSRSPSSTLSGPDL 897

Query: 359  LSLFED-TFVPEISVTTPSQFE-----APGPFSEQASLLDLDFD--PLPPVTSPVKAPTP 410
                   T  PE      S  E     +P P +E A+     +   P PP+     AP  
Sbjct: 898  AGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFR-GAP-- 954

Query: 411  SGQSIPWDLWEPTESPAGSLPSGEPSAAEGTFAV----SWPSQTAEPGPAQPAEASEVAG 466
             G  +PW             P+  P +A+G   +       S T  PG   P  +   +G
Sbjct: 955  -GAPLPWP------------PATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSG 1001

Query: 467  GTQPA-----AGAQEPGETAASEAASSSLPAVVVE-----TFPATVNGTVEGGSGAG 513
            G   A     A ++ P +    E    +L A VV+     T          GGSG G
Sbjct: 1002 GKAAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAEGAAGGSGGG 1058



 Score = 38.5 bits (88), Expect = 0.018
 Identities = 56/223 (25%), Positives = 73/223 (32%), Gaps = 46/223 (20%)

Query: 283 AQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPP-- 340
           A PS  AP            SP  +P ++    P  +   +P AT P         PP  
Sbjct: 646 ATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQ 705

Query: 341 VPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPSQFEAPGPFSEQASLLDLDFDPLPP 400
           VPP P  +P                     S T P Q  AP P +       L   P PP
Sbjct: 706 VPPSPPASPPMSP-----------------SATPPPQ--APPPLAAP----PLQVPPSPP 742

Query: 401 VTSPVKAPTPSGQSIPWDLWEP----TESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPA 456
            + P+         +P  L  P      SP  SLP                S  A+P P 
Sbjct: 743 ASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPM---------------SPLAKPPPQ 787

Query: 457 QPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFP 499
            P   +       P+  A  PG+  A  + S+SLP   + T P
Sbjct: 788 APPALATPPLQALPSPPASFPGQ--APFSPSASLPMSPLATPP 828



 Score = 38.1 bits (87), Expect = 0.023
 Identities = 56/226 (24%), Positives = 74/226 (32%), Gaps = 30/226 (13%)

Query: 285 PSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATL----PKSPSQLRKGPP 340
           P +N P+     P     +P  TP +     P P     P + L    P++PS +   PP
Sbjct: 534 PLENLPSLA-PPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPP 592

Query: 341 VPPP----------------PKHTPSKEVKQEQILSLFEDTFVPEISVTTPSQFEAPGPF 384
             PP                P  TP  +      L   +    P  S    S    P P 
Sbjct: 593 QAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPL-SPLATPSPQ 651

Query: 385 SEQASLLDLDFDPL-PPVTSPVKAPTPSGQSIPWDLWEPTESPAGSLPSGEPSAAEGTFA 443
           +  A  + L   P  PP + PV+AP     S       P  SP+ + PS  P +      
Sbjct: 652 APNALAVHLLQAPFSPPPSPPVQAPFSPPAS-------PPVSPSATPPSQAPPSLAAPPL 704

Query: 444 VSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGETAASEAASSS 489
              PS  A P  +  A     A     A   Q P    AS   S S
Sbjct: 705 QVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPS 750



 Score = 35.8 bits (81), Expect = 0.11
 Identities = 60/234 (25%), Positives = 80/234 (34%), Gaps = 32/234 (13%)

Query: 283 AQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLP--KSPSQLRKGPP 340
           A PS +AP      PSPP   P+  P               P  T P  ++P  L+  PP
Sbjct: 344 APPSPSAPPSLQTLPSPPATPPSQAP---------------PSMTTPPMQAPPSLQTIPP 388

Query: 341 VPPPPKHT-PSKEVKQEQIL--SLFEDTFVPEISVTTPSQFEAPGPFSEQASLLDLDFD- 396
           +  P   T PS +     +   SL   T +   ++     F    P   QASL       
Sbjct: 389 IQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPA 448

Query: 397 PLPPVTSPVKAPTPSGQSIPWDL-WEPTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGP 455
             PP + P++AP     S P      P  SP  S  +  P  A  + A   P        
Sbjct: 449 STPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLI 508

Query: 456 AQPAEASEVAG----GTQPAAGAQEPGETAAS------EAASSSLPAVVVETFP 499
             P E           T PA+    P E   S      + AS+ L    +ET P
Sbjct: 509 MPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPP 562


>gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Homo
           sapiens]
          Length = 1188

 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 66/239 (27%), Positives = 82/239 (34%), Gaps = 34/239 (14%)

Query: 297 PSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPV----PPPPKHTPSKE 352
           P PP G PA  P   ++   EP G    G+ LP  PS     PP+    PPPP   P   
Sbjct: 140 PPPPPG-PAPGPPQDIS---EPPG----GSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPP 191

Query: 353 VKQEQILSLFEDTFVPEISVTTPSQFEAPGPFSEQASLLDLDFDPLPPVTSPVKAPTPSG 412
              E   +L     +   S+ TP  F  P P         L F  L P   PV AP P  
Sbjct: 192 PVLE---ALSPPHTLSSPSIPTPPDFIPPAP--------PLAF--LAPPPPPVPAPAPPA 238

Query: 413 QSIPWDLWEPTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQPAA 472
            + P  +      P G        A  G  A      T    P  PAE    A G  P  
Sbjct: 239 PASPHTVGTRLFPPGGVTKWKSDVALNGRQA----EATRASPPRSPAEPKGSALGPNPEP 294

Query: 473 GAQEPGE---TAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQ 528
               P        +   +SS+P    +  P    G  +      RL LPP F  +  +Q
Sbjct: 295 HLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATK--KAPSRLPLPPSFHIRPASQ 351



 Score = 33.9 bits (76), Expect = 0.43
 Identities = 61/257 (23%), Positives = 90/257 (35%), Gaps = 58/257 (22%)

Query: 278 TFTVKAQPSDNAPAKGN----KSPS----PPDGSPAATPEIRVNHEPEPAGGATPGATLP 329
           T ++  Q +  AP K      K+PS    PP        ++  +  PEP       AT P
Sbjct: 312 TSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAP 371

Query: 330 KSP--------SQLRKGPPVPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPSQFEAP 381
            SP        +  R G P P PP   P+  +              P +    P     P
Sbjct: 372 ASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPP----------APPLPPAAP-----P 416

Query: 382 GPFSEQASLLDLDFDPLPPVTSPVKAPTP-------SGQSIPWDLWEPTE-----SPAGS 429
            P +++A+     F   P  +SP   P P       +  S P D  +P++     +   +
Sbjct: 417 LPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNELAA 476

Query: 430 LPSGEPSAAEGTFAVSWPSQTAEP-------GPAQPAE---ASEVAGGTQPAAGAQEPGE 479
              G  S  E  F    P  T  P       GP  P +    S  A  T P    +  G 
Sbjct: 477 YLCG--SRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVPEKSLGG 534

Query: 480 TAASE---AASSSLPAV 493
           ++ +E   A S +LP+V
Sbjct: 535 SSLTETEAAPSLTLPSV 551


>gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Homo
           sapiens]
          Length = 1188

 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 66/239 (27%), Positives = 82/239 (34%), Gaps = 34/239 (14%)

Query: 297 PSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPV----PPPPKHTPSKE 352
           P PP G PA  P   ++   EP G    G+ LP  PS     PP+    PPPP   P   
Sbjct: 140 PPPPPG-PAPGPPQDIS---EPPG----GSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPP 191

Query: 353 VKQEQILSLFEDTFVPEISVTTPSQFEAPGPFSEQASLLDLDFDPLPPVTSPVKAPTPSG 412
              E   +L     +   S+ TP  F  P P         L F  L P   PV AP P  
Sbjct: 192 PVLE---ALSPPHTLSSPSIPTPPDFIPPAP--------PLAF--LAPPPPPVPAPAPPA 238

Query: 413 QSIPWDLWEPTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQPAA 472
            + P  +      P G        A  G  A      T    P  PAE    A G  P  
Sbjct: 239 PASPHTVGTRLFPPGGVTKWKSDVALNGRQA----EATRASPPRSPAEPKGSALGPNPEP 294

Query: 473 GAQEPGE---TAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQ 528
               P        +   +SS+P    +  P    G  +      RL LPP F  +  +Q
Sbjct: 295 HLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATK--KAPSRLPLPPSFHIRPASQ 351



 Score = 33.9 bits (76), Expect = 0.43
 Identities = 61/257 (23%), Positives = 90/257 (35%), Gaps = 58/257 (22%)

Query: 278 TFTVKAQPSDNAPAKGN----KSPS----PPDGSPAATPEIRVNHEPEPAGGATPGATLP 329
           T ++  Q +  AP K      K+PS    PP        ++  +  PEP       AT P
Sbjct: 312 TSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAP 371

Query: 330 KSP--------SQLRKGPPVPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPSQFEAP 381
            SP        +  R G P P PP   P+  +              P +    P     P
Sbjct: 372 ASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPP----------APPLPPAAP-----P 416

Query: 382 GPFSEQASLLDLDFDPLPPVTSPVKAPTP-------SGQSIPWDLWEPTE-----SPAGS 429
            P +++A+     F   P  +SP   P P       +  S P D  +P++     +   +
Sbjct: 417 LPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNELAA 476

Query: 430 LPSGEPSAAEGTFAVSWPSQTAEP-------GPAQPAE---ASEVAGGTQPAAGAQEPGE 479
              G  S  E  F    P  T  P       GP  P +    S  A  T P    +  G 
Sbjct: 477 YLCG--SRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVPEKSLGG 534

Query: 480 TAASE---AASSSLPAV 493
           ++ +E   A S +LP+V
Sbjct: 535 SSLTETEAAPSLTLPSV 551


>gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo
           sapiens]
          Length = 1188

 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 66/239 (27%), Positives = 82/239 (34%), Gaps = 34/239 (14%)

Query: 297 PSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPV----PPPPKHTPSKE 352
           P PP G PA  P   ++   EP G    G+ LP  PS     PP+    PPPP   P   
Sbjct: 140 PPPPPG-PAPGPPQDIS---EPPG----GSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPP 191

Query: 353 VKQEQILSLFEDTFVPEISVTTPSQFEAPGPFSEQASLLDLDFDPLPPVTSPVKAPTPSG 412
              E   +L     +   S+ TP  F  P P         L F  L P   PV AP P  
Sbjct: 192 PVLE---ALSPPHTLSSPSIPTPPDFIPPAP--------PLAF--LAPPPPPVPAPAPPA 238

Query: 413 QSIPWDLWEPTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQPAA 472
            + P  +      P G        A  G  A      T    P  PAE    A G  P  
Sbjct: 239 PASPHTVGTRLFPPGGVTKWKSDVALNGRQA----EATRASPPRSPAEPKGSALGPNPEP 294

Query: 473 GAQEPGE---TAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQ 528
               P        +   +SS+P    +  P    G  +      RL LPP F  +  +Q
Sbjct: 295 HLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATK--KAPSRLPLPPSFHIRPASQ 351



 Score = 33.9 bits (76), Expect = 0.43
 Identities = 61/257 (23%), Positives = 90/257 (35%), Gaps = 58/257 (22%)

Query: 278 TFTVKAQPSDNAPAKGN----KSPS----PPDGSPAATPEIRVNHEPEPAGGATPGATLP 329
           T ++  Q +  AP K      K+PS    PP        ++  +  PEP       AT P
Sbjct: 312 TSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAP 371

Query: 330 KSP--------SQLRKGPPVPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPSQFEAP 381
            SP        +  R G P P PP   P+  +              P +    P     P
Sbjct: 372 ASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPP----------APPLPPAAP-----P 416

Query: 382 GPFSEQASLLDLDFDPLPPVTSPVKAPTP-------SGQSIPWDLWEPTE-----SPAGS 429
            P +++A+     F   P  +SP   P P       +  S P D  +P++     +   +
Sbjct: 417 LPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNELAA 476

Query: 430 LPSGEPSAAEGTFAVSWPSQTAEP-------GPAQPAE---ASEVAGGTQPAAGAQEPGE 479
              G  S  E  F    P  T  P       GP  P +    S  A  T P    +  G 
Sbjct: 477 YLCG--SRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVPEKSLGG 534

Query: 480 TAASE---AASSSLPAV 493
           ++ +E   A S +LP+V
Sbjct: 535 SSLTETEAAPSLTLPSV 551


>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
          Length = 1270

 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 57/230 (24%), Positives = 76/230 (33%), Gaps = 13/230 (5%)

Query: 282 KAQPSDNAP-AKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPK--SPSQLRKG 338
           K    D AP +K    P+P   +    P +    EP P     P +T PK  +P+ ++  
Sbjct: 181 KTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSA 240

Query: 339 PPVPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPSQFEAPGPFSEQASLLDLDFDPL 398
           P  P  P  T +K             T   E + TTP +  AP    E A          
Sbjct: 241 PTTPKEPAPTTTKSAPTTP--KEPAPTTTKEPAPTTPKE-PAPTTTKEPAPTTTKSAPTT 297

Query: 399 P----PVTSPVKAPTPSGQSIPWDLWEPTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPG 454
           P    P T    APT   +  P    EPT +            A  T     P+   +P 
Sbjct: 298 PKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPA 357

Query: 455 PAQPAEASEVAGGTQPAAGAQEPGETAASEAA---SSSLPAVVVETFPAT 501
           P  P E +            +EP  T   E A   + S P    E  P T
Sbjct: 358 PTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTT 407



 Score = 50.4 bits (119), Expect = 4e-06
 Identities = 63/251 (25%), Positives = 85/251 (33%), Gaps = 32/251 (12%)

Query: 285 PSDNAPAKGNKSPSPPDGSPAAT----PEIRVNHEPEPAGGATPGATLPKSPSQLRKGPP 340
           P + AP     +P+ P   PA T    P      EP P     P  T  K PS      P
Sbjct: 330 PKEPAPTTKEPAPTTPK-EPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEP 388

Query: 341 VPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTT-----PSQFEAPGPFSEQASLLDLDF 395
            P   K  P+   +     +    T   E S TT     P+  + P P + +        
Sbjct: 389 APTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPK 448

Query: 396 DPLPPVTSPVKAPTPSGQSIPWDLWEPT-ESPAGSLPSGEPSAAEGTFAVSWPSQTAEPG 454
           +P  P T    APT + +  P    EP   +P  + P+        T     P+   +P 
Sbjct: 449 EP-APTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPA 507

Query: 455 PAQPAEAS------------EVAGGTQPAAGA----QEPGETAASEAASSS----LPAVV 494
           P  P E +            E    T P A A    +EP  T   E A ++     P   
Sbjct: 508 PTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTP 567

Query: 495 VETFPATVNGT 505
            ET P T  GT
Sbjct: 568 KETAPTTPKGT 578



 Score = 50.1 bits (118), Expect = 6e-06
 Identities = 58/230 (25%), Positives = 81/230 (35%), Gaps = 25/230 (10%)

Query: 280 TVKAQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGP 339
           T   +P+         +P  P  +    P      EP P     P  T PK P+   K P
Sbjct: 281 TTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEP 340

Query: 340 PVPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPSQFEAPGPFSEQASLLDLDFDPLP 399
               P +  P+   K          T   E + TTP +   P P + +        +P P
Sbjct: 341 APTTPKEPAPTAPKKP-------APTTPKEPAPTTPKE---PAPTTTKEPSPTTPKEPAP 390

Query: 400 ------PVTSPVKAPTPSGQSIPWDLWEP----TESPAGSLPSGEPSAAEGTFAVSWPSQ 449
                 P T+   APT + +S P    EP    T+ PA + P  EP  A  T     P+ 
Sbjct: 391 TTTKSAPTTTKEPAPTTT-KSAPTTPKEPSPTTTKEPAPTTPK-EP--APTTPKKPAPTT 446

Query: 450 TAEPGPAQPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFP 499
             EP P  P E +            +EP  T   E A ++ P  +  T P
Sbjct: 447 PKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTT-PKKLTPTTP 495



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 60/227 (26%), Positives = 80/227 (35%), Gaps = 35/227 (15%)

Query: 280 TVKAQPS---DNAPAKGNKSPSPP-DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQL 335
           T K+ P+   + AP     +P+ P + SP  T E       EPA   TP    P +P + 
Sbjct: 392 TTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAP-TTPKKPAPTTPKEP 450

Query: 336 RKGPPVPPPPKHT--PSKEVKQEQILSLFEDTFVPEISVTTPSQFEAPGPFSEQASLLDL 393
               P  P P  T  P+    +E        T   E + TTP +     P          
Sbjct: 451 APTTPKEPAPTTTKKPAPTTPKEP-----APTTPKETAPTTPKKLTPTTP---------- 495

Query: 394 DFDPLPPVTSPVKAPTPSGQSIPWDLWEPT-ESPAGSLPSGEPSAAEGTFAVSWPSQTAE 452
             + L P T    APT   +  P    EPT  +P    P+   +AA  T     P+   E
Sbjct: 496 --EKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKE 553

Query: 453 PGPAQPAE---------ASEVAGGTQPAAGAQEPGETAASEAASSSL 490
           P P  P E         A     GT P    +EP  T   + A   L
Sbjct: 554 PAPTTPKEPAPTTPKETAPTTPKGTAPTT-LKEPAPTTPKKPAPKEL 599



 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 58/242 (23%), Positives = 82/242 (33%), Gaps = 24/242 (9%)

Query: 285 PSDNAPAKGNKSPSPP-DGSPAAT--PEIRVNHEPEPAGGATP-------GATLPKSPSQ 334
           P + AP     +P+ P + +P  T  P      EP P     P         T PK P+ 
Sbjct: 244 PKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAP 303

Query: 335 LRKGPPVPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPSQFEAPGPFSEQASLLDLD 394
                P P  PK       K+    +  E    P      P+  + P P + +       
Sbjct: 304 TTPKKPAPTTPKEPAPTTPKEPTPTTPKEP--APTTKEPAPTTPKEPAPTAPKKPAPTTP 361

Query: 395 FDPLPPVTSPVKAPTPSGQSIPWDLWEPTESPAGSLP--SGEPS-----AAEGTFAVSWP 447
            +P  P T    APT + +  P    EP  +   S P  + EP+     +A  T     P
Sbjct: 362 KEP-APTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSP 420

Query: 448 SQTAEPGPAQPAEASEVAGGTQPAAGAQEPGETAASEAASSS----LPAVVVETFPATVN 503
           + T EP P  P E +            +EP  T   E A ++     P    E  P T  
Sbjct: 421 TTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPK 480

Query: 504 GT 505
            T
Sbjct: 481 ET 482



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 56/238 (23%), Positives = 84/238 (35%), Gaps = 32/238 (13%)

Query: 280 TVKAQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGP 339
           T   +P+   P +   +P+ P  +   TP+     EP P     P  T PK P+      
Sbjct: 517 TTPEEPTPTTPEE--PAPTTPKAAAPNTPK-----EPAPTTPKEPAPTTPKEPAPTTPKE 569

Query: 340 PVPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPSQ-----FEAPGPFSEQASLLDLD 394
             P  PK T    +K E   +  +     E++ TT  +      + P P + + +     
Sbjct: 570 TAPTTPKGTAPTTLK-EPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTP 628

Query: 395 FDPLPPVTSPVKAPTPSGQSIPWDLWEPTESP---------AGSLPSGEPSAAEGTFAVS 445
            +P  P T    APT    + P  L EP  +          A +   G  S      A +
Sbjct: 629 KEP-APTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPT 687

Query: 446 WPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVN 503
            P +TA   P +PA        T P   A    ET     +  S P    E  P T++
Sbjct: 688 TPKETAPTTPKEPAP-------TTPKKPAPTTPETPPPTTSEVSTPTTTKE--PTTIH 736



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 58/231 (25%), Positives = 78/231 (33%), Gaps = 17/231 (7%)

Query: 296 SPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPPPKHTPSKEVKQ 355
           +P+ P G+   TP+     EP P     P  T PK  +      P P  PK    KE+  
Sbjct: 616 APTTPKGTAPTTPK-----EPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAP 670

Query: 356 EQILSLFEDTFVPEISVTTPSQFEAPGPFSEQASLLDLDFDPLPPVTSPVKAPTPSGQSI 415
                    T   + + TTP +  AP    E A        P  P T P   PT S  S 
Sbjct: 671 TTTKGP-TSTTSDKPAPTTPKE-TAPTTPKEPAPTTPKKPAPTTPETPP---PTTSEVST 725

Query: 416 PWDLWEPT---ESPAGSLP--SGEPS--AAEGTFAVSWPSQTAEPGPAQPAEASEVAGGT 468
           P    EPT   +SP  S P  S EP+  A E +        T  P   +P   +     T
Sbjct: 726 PTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKT 785

Query: 469 QPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPP 519
                   P  T A+   +        +T  + +  T    +     D  P
Sbjct: 786 TERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTP 836



 Score = 30.0 bits (66), Expect = 6.3
 Identities = 26/107 (24%), Positives = 38/107 (35%), Gaps = 6/107 (5%)

Query: 278 TFTVKAQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRK 337
           T    A  +   PA    +P+   G  + T +      P+     TP    P +P +   
Sbjct: 651 TLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAP 710

Query: 338 GPPVPPPPK----HTPSKEVKQEQILSLFEDTFVPEISV-TTPSQFE 379
             P  PPP      TP+   K+   +    D   PE+S   TP   E
Sbjct: 711 TTPETPPPTTSEVSTPT-TTKEPTTIHKSPDESTPELSAEPTPKALE 756


>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
          Length = 1311

 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 57/230 (24%), Positives = 76/230 (33%), Gaps = 13/230 (5%)

Query: 282 KAQPSDNAP-AKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPK--SPSQLRKG 338
           K    D AP +K    P+P   +    P +    EP P     P +T PK  +P+ ++  
Sbjct: 222 KTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSA 281

Query: 339 PPVPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPSQFEAPGPFSEQASLLDLDFDPL 398
           P  P  P  T +K             T   E + TTP +  AP    E A          
Sbjct: 282 PTTPKEPAPTTTKSAPTTP--KEPAPTTTKEPAPTTPKE-PAPTTTKEPAPTTTKSAPTT 338

Query: 399 P----PVTSPVKAPTPSGQSIPWDLWEPTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPG 454
           P    P T    APT   +  P    EPT +            A  T     P+   +P 
Sbjct: 339 PKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPA 398

Query: 455 PAQPAEASEVAGGTQPAAGAQEPGETAASEAA---SSSLPAVVVETFPAT 501
           P  P E +            +EP  T   E A   + S P    E  P T
Sbjct: 399 PTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTT 448



 Score = 50.4 bits (119), Expect = 4e-06
 Identities = 63/251 (25%), Positives = 85/251 (33%), Gaps = 32/251 (12%)

Query: 285 PSDNAPAKGNKSPSPPDGSPAAT----PEIRVNHEPEPAGGATPGATLPKSPSQLRKGPP 340
           P + AP     +P+ P   PA T    P      EP P     P  T  K PS      P
Sbjct: 371 PKEPAPTTKEPAPTTPK-EPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEP 429

Query: 341 VPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTT-----PSQFEAPGPFSEQASLLDLDF 395
            P   K  P+   +     +    T   E S TT     P+  + P P + +        
Sbjct: 430 APTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPK 489

Query: 396 DPLPPVTSPVKAPTPSGQSIPWDLWEPT-ESPAGSLPSGEPSAAEGTFAVSWPSQTAEPG 454
           +P  P T    APT + +  P    EP   +P  + P+        T     P+   +P 
Sbjct: 490 EP-APTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPA 548

Query: 455 PAQPAEAS------------EVAGGTQPAAGA----QEPGETAASEAASSS----LPAVV 494
           P  P E +            E    T P A A    +EP  T   E A ++     P   
Sbjct: 549 PTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTP 608

Query: 495 VETFPATVNGT 505
            ET P T  GT
Sbjct: 609 KETAPTTPKGT 619



 Score = 50.1 bits (118), Expect = 6e-06
 Identities = 58/230 (25%), Positives = 81/230 (35%), Gaps = 25/230 (10%)

Query: 280 TVKAQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGP 339
           T   +P+         +P  P  +    P      EP P     P  T PK P+   K P
Sbjct: 322 TTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEP 381

Query: 340 PVPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPSQFEAPGPFSEQASLLDLDFDPLP 399
               P +  P+   K          T   E + TTP +   P P + +        +P P
Sbjct: 382 APTTPKEPAPTAPKKP-------APTTPKEPAPTTPKE---PAPTTTKEPSPTTPKEPAP 431

Query: 400 ------PVTSPVKAPTPSGQSIPWDLWEP----TESPAGSLPSGEPSAAEGTFAVSWPSQ 449
                 P T+   APT + +S P    EP    T+ PA + P  EP  A  T     P+ 
Sbjct: 432 TTTKSAPTTTKEPAPTTT-KSAPTTPKEPSPTTTKEPAPTTPK-EP--APTTPKKPAPTT 487

Query: 450 TAEPGPAQPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFP 499
             EP P  P E +            +EP  T   E A ++ P  +  T P
Sbjct: 488 PKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTT-PKKLTPTTP 536



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 60/227 (26%), Positives = 80/227 (35%), Gaps = 35/227 (15%)

Query: 280 TVKAQPS---DNAPAKGNKSPSPP-DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQL 335
           T K+ P+   + AP     +P+ P + SP  T E       EPA   TP    P +P + 
Sbjct: 433 TTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAP-TTPKKPAPTTPKEP 491

Query: 336 RKGPPVPPPPKHT--PSKEVKQEQILSLFEDTFVPEISVTTPSQFEAPGPFSEQASLLDL 393
               P  P P  T  P+    +E        T   E + TTP +     P          
Sbjct: 492 APTTPKEPAPTTTKKPAPTTPKEP-----APTTPKETAPTTPKKLTPTTP---------- 536

Query: 394 DFDPLPPVTSPVKAPTPSGQSIPWDLWEPT-ESPAGSLPSGEPSAAEGTFAVSWPSQTAE 452
             + L P T    APT   +  P    EPT  +P    P+   +AA  T     P+   E
Sbjct: 537 --EKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKE 594

Query: 453 PGPAQPAE---------ASEVAGGTQPAAGAQEPGETAASEAASSSL 490
           P P  P E         A     GT P    +EP  T   + A   L
Sbjct: 595 PAPTTPKEPAPTTPKETAPTTPKGTAPTT-LKEPAPTTPKKPAPKEL 640



 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 58/242 (23%), Positives = 82/242 (33%), Gaps = 24/242 (9%)

Query: 285 PSDNAPAKGNKSPSPP-DGSPAAT--PEIRVNHEPEPAGGATP-------GATLPKSPSQ 334
           P + AP     +P+ P + +P  T  P      EP P     P         T PK P+ 
Sbjct: 285 PKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAP 344

Query: 335 LRKGPPVPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPSQFEAPGPFSEQASLLDLD 394
                P P  PK       K+    +  E    P      P+  + P P + +       
Sbjct: 345 TTPKKPAPTTPKEPAPTTPKEPTPTTPKEP--APTTKEPAPTTPKEPAPTAPKKPAPTTP 402

Query: 395 FDPLPPVTSPVKAPTPSGQSIPWDLWEPTESPAGSLP--SGEPS-----AAEGTFAVSWP 447
            +P  P T    APT + +  P    EP  +   S P  + EP+     +A  T     P
Sbjct: 403 KEP-APTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSP 461

Query: 448 SQTAEPGPAQPAEASEVAGGTQPAAGAQEPGETAASEAASSS----LPAVVVETFPATVN 503
           + T EP P  P E +            +EP  T   E A ++     P    E  P T  
Sbjct: 462 TTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPK 521

Query: 504 GT 505
            T
Sbjct: 522 ET 523



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 56/238 (23%), Positives = 84/238 (35%), Gaps = 32/238 (13%)

Query: 280 TVKAQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGP 339
           T   +P+   P +   +P+ P  +   TP+     EP P     P  T PK P+      
Sbjct: 558 TTPEEPTPTTPEE--PAPTTPKAAAPNTPK-----EPAPTTPKEPAPTTPKEPAPTTPKE 610

Query: 340 PVPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPSQ-----FEAPGPFSEQASLLDLD 394
             P  PK T    +K E   +  +     E++ TT  +      + P P + + +     
Sbjct: 611 TAPTTPKGTAPTTLK-EPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTP 669

Query: 395 FDPLPPVTSPVKAPTPSGQSIPWDLWEPTESP---------AGSLPSGEPSAAEGTFAVS 445
            +P  P T    APT    + P  L EP  +          A +   G  S      A +
Sbjct: 670 KEP-APTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPT 728

Query: 446 WPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVN 503
            P +TA   P +PA        T P   A    ET     +  S P    E  P T++
Sbjct: 729 TPKETAPTTPKEPAP-------TTPKKPAPTTPETPPPTTSEVSTPTTTKE--PTTIH 777



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 58/231 (25%), Positives = 78/231 (33%), Gaps = 17/231 (7%)

Query: 296 SPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPPPKHTPSKEVKQ 355
           +P+ P G+   TP+     EP P     P  T PK  +      P P  PK    KE+  
Sbjct: 657 APTTPKGTAPTTPK-----EPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAP 711

Query: 356 EQILSLFEDTFVPEISVTTPSQFEAPGPFSEQASLLDLDFDPLPPVTSPVKAPTPSGQSI 415
                    T   + + TTP +  AP    E A        P  P T P   PT S  S 
Sbjct: 712 TTTKGP-TSTTSDKPAPTTPKE-TAPTTPKEPAPTTPKKPAPTTPETPP---PTTSEVST 766

Query: 416 PWDLWEPT---ESPAGSLP--SGEPS--AAEGTFAVSWPSQTAEPGPAQPAEASEVAGGT 468
           P    EPT   +SP  S P  S EP+  A E +        T  P   +P   +     T
Sbjct: 767 PTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKT 826

Query: 469 QPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPP 519
                   P  T A+   +        +T  + +  T    +     D  P
Sbjct: 827 TERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTP 877



 Score = 30.0 bits (66), Expect = 6.3
 Identities = 26/107 (24%), Positives = 38/107 (35%), Gaps = 6/107 (5%)

Query: 278 TFTVKAQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRK 337
           T    A  +   PA    +P+   G  + T +      P+     TP    P +P +   
Sbjct: 692 TLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAP 751

Query: 338 GPPVPPPPK----HTPSKEVKQEQILSLFEDTFVPEISV-TTPSQFE 379
             P  PPP      TP+   K+   +    D   PE+S   TP   E
Sbjct: 752 TTPETPPPTTSEVSTPT-TTKEPTTIHKSPDESTPELSAEPTPKALE 797


>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
          Length = 1363

 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 57/230 (24%), Positives = 76/230 (33%), Gaps = 13/230 (5%)

Query: 282 KAQPSDNAP-AKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPK--SPSQLRKG 338
           K    D AP +K    P+P   +    P +    EP P     P +T PK  +P+ ++  
Sbjct: 274 KTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSA 333

Query: 339 PPVPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPSQFEAPGPFSEQASLLDLDFDPL 398
           P  P  P  T +K             T   E + TTP +  AP    E A          
Sbjct: 334 PTTPKEPAPTTTKSAPTTP--KEPAPTTTKEPAPTTPKE-PAPTTTKEPAPTTTKSAPTT 390

Query: 399 P----PVTSPVKAPTPSGQSIPWDLWEPTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPG 454
           P    P T    APT   +  P    EPT +            A  T     P+   +P 
Sbjct: 391 PKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPA 450

Query: 455 PAQPAEASEVAGGTQPAAGAQEPGETAASEAA---SSSLPAVVVETFPAT 501
           P  P E +            +EP  T   E A   + S P    E  P T
Sbjct: 451 PTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTT 500



 Score = 50.4 bits (119), Expect = 4e-06
 Identities = 63/251 (25%), Positives = 85/251 (33%), Gaps = 32/251 (12%)

Query: 285 PSDNAPAKGNKSPSPPDGSPAAT----PEIRVNHEPEPAGGATPGATLPKSPSQLRKGPP 340
           P + AP     +P+ P   PA T    P      EP P     P  T  K PS      P
Sbjct: 423 PKEPAPTTKEPAPTTPK-EPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEP 481

Query: 341 VPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTT-----PSQFEAPGPFSEQASLLDLDF 395
            P   K  P+   +     +    T   E S TT     P+  + P P + +        
Sbjct: 482 APTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPK 541

Query: 396 DPLPPVTSPVKAPTPSGQSIPWDLWEPT-ESPAGSLPSGEPSAAEGTFAVSWPSQTAEPG 454
           +P  P T    APT + +  P    EP   +P  + P+        T     P+   +P 
Sbjct: 542 EP-APTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPA 600

Query: 455 PAQPAEAS------------EVAGGTQPAAGA----QEPGETAASEAASSS----LPAVV 494
           P  P E +            E    T P A A    +EP  T   E A ++     P   
Sbjct: 601 PTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTP 660

Query: 495 VETFPATVNGT 505
            ET P T  GT
Sbjct: 661 KETAPTTPKGT 671



 Score = 50.1 bits (118), Expect = 6e-06
 Identities = 58/230 (25%), Positives = 81/230 (35%), Gaps = 25/230 (10%)

Query: 280 TVKAQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGP 339
           T   +P+         +P  P  +    P      EP P     P  T PK P+   K P
Sbjct: 374 TTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEP 433

Query: 340 PVPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPSQFEAPGPFSEQASLLDLDFDPLP 399
               P +  P+   K          T   E + TTP +   P P + +        +P P
Sbjct: 434 APTTPKEPAPTAPKKP-------APTTPKEPAPTTPKE---PAPTTTKEPSPTTPKEPAP 483

Query: 400 ------PVTSPVKAPTPSGQSIPWDLWEP----TESPAGSLPSGEPSAAEGTFAVSWPSQ 449
                 P T+   APT + +S P    EP    T+ PA + P  EP  A  T     P+ 
Sbjct: 484 TTTKSAPTTTKEPAPTTT-KSAPTTPKEPSPTTTKEPAPTTPK-EP--APTTPKKPAPTT 539

Query: 450 TAEPGPAQPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFP 499
             EP P  P E +            +EP  T   E A ++ P  +  T P
Sbjct: 540 PKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTT-PKKLTPTTP 588



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 60/227 (26%), Positives = 80/227 (35%), Gaps = 35/227 (15%)

Query: 280 TVKAQPS---DNAPAKGNKSPSPP-DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQL 335
           T K+ P+   + AP     +P+ P + SP  T E       EPA   TP    P +P + 
Sbjct: 485 TTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAP-TTPKKPAPTTPKEP 543

Query: 336 RKGPPVPPPPKHT--PSKEVKQEQILSLFEDTFVPEISVTTPSQFEAPGPFSEQASLLDL 393
               P  P P  T  P+    +E        T   E + TTP +     P          
Sbjct: 544 APTTPKEPAPTTTKKPAPTTPKEP-----APTTPKETAPTTPKKLTPTTP---------- 588

Query: 394 DFDPLPPVTSPVKAPTPSGQSIPWDLWEPT-ESPAGSLPSGEPSAAEGTFAVSWPSQTAE 452
             + L P T    APT   +  P    EPT  +P    P+   +AA  T     P+   E
Sbjct: 589 --EKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKE 646

Query: 453 PGPAQPAE---------ASEVAGGTQPAAGAQEPGETAASEAASSSL 490
           P P  P E         A     GT P    +EP  T   + A   L
Sbjct: 647 PAPTTPKEPAPTTPKETAPTTPKGTAPTT-LKEPAPTTPKKPAPKEL 692



 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 58/242 (23%), Positives = 82/242 (33%), Gaps = 24/242 (9%)

Query: 285 PSDNAPAKGNKSPSPP-DGSPAAT--PEIRVNHEPEPAGGATP-------GATLPKSPSQ 334
           P + AP     +P+ P + +P  T  P      EP P     P         T PK P+ 
Sbjct: 337 PKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAP 396

Query: 335 LRKGPPVPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPSQFEAPGPFSEQASLLDLD 394
                P P  PK       K+    +  E    P      P+  + P P + +       
Sbjct: 397 TTPKKPAPTTPKEPAPTTPKEPTPTTPKEP--APTTKEPAPTTPKEPAPTAPKKPAPTTP 454

Query: 395 FDPLPPVTSPVKAPTPSGQSIPWDLWEPTESPAGSLP--SGEPS-----AAEGTFAVSWP 447
            +P  P T    APT + +  P    EP  +   S P  + EP+     +A  T     P
Sbjct: 455 KEP-APTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSP 513

Query: 448 SQTAEPGPAQPAEASEVAGGTQPAAGAQEPGETAASEAASSS----LPAVVVETFPATVN 503
           + T EP P  P E +            +EP  T   E A ++     P    E  P T  
Sbjct: 514 TTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPK 573

Query: 504 GT 505
            T
Sbjct: 574 ET 575



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 56/238 (23%), Positives = 84/238 (35%), Gaps = 32/238 (13%)

Query: 280 TVKAQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGP 339
           T   +P+   P +   +P+ P  +   TP+     EP P     P  T PK P+      
Sbjct: 610 TTPEEPTPTTPEE--PAPTTPKAAAPNTPK-----EPAPTTPKEPAPTTPKEPAPTTPKE 662

Query: 340 PVPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPSQ-----FEAPGPFSEQASLLDLD 394
             P  PK T    +K E   +  +     E++ TT  +      + P P + + +     
Sbjct: 663 TAPTTPKGTAPTTLK-EPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTP 721

Query: 395 FDPLPPVTSPVKAPTPSGQSIPWDLWEPTESP---------AGSLPSGEPSAAEGTFAVS 445
            +P  P T    APT    + P  L EP  +          A +   G  S      A +
Sbjct: 722 KEP-APTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPT 780

Query: 446 WPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVN 503
            P +TA   P +PA        T P   A    ET     +  S P    E  P T++
Sbjct: 781 TPKETAPTTPKEPAP-------TTPKKPAPTTPETPPPTTSEVSTPTTTKE--PTTIH 829



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 58/231 (25%), Positives = 78/231 (33%), Gaps = 17/231 (7%)

Query: 296 SPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPPPKHTPSKEVKQ 355
           +P+ P G+   TP+     EP P     P  T PK  +      P P  PK    KE+  
Sbjct: 709 APTTPKGTAPTTPK-----EPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAP 763

Query: 356 EQILSLFEDTFVPEISVTTPSQFEAPGPFSEQASLLDLDFDPLPPVTSPVKAPTPSGQSI 415
                    T   + + TTP +  AP    E A        P  P T P   PT S  S 
Sbjct: 764 TTTKGP-TSTTSDKPAPTTPKE-TAPTTPKEPAPTTPKKPAPTTPETPP---PTTSEVST 818

Query: 416 PWDLWEPT---ESPAGSLP--SGEPS--AAEGTFAVSWPSQTAEPGPAQPAEASEVAGGT 468
           P    EPT   +SP  S P  S EP+  A E +        T  P   +P   +     T
Sbjct: 819 PTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKT 878

Query: 469 QPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPP 519
                   P  T A+   +        +T  + +  T    +     D  P
Sbjct: 879 TERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTP 929



 Score = 30.0 bits (66), Expect = 6.3
 Identities = 26/107 (24%), Positives = 38/107 (35%), Gaps = 6/107 (5%)

Query: 278 TFTVKAQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRK 337
           T    A  +   PA    +P+   G  + T +      P+     TP    P +P +   
Sbjct: 744 TLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAP 803

Query: 338 GPPVPPPPK----HTPSKEVKQEQILSLFEDTFVPEISV-TTPSQFE 379
             P  PPP      TP+   K+   +    D   PE+S   TP   E
Sbjct: 804 TTPETPPPTTSEVSTPT-TTKEPTTIHKSPDESTPELSAEPTPKALE 849


>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
          Length = 1404

 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 57/230 (24%), Positives = 76/230 (33%), Gaps = 13/230 (5%)

Query: 282 KAQPSDNAP-AKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPK--SPSQLRKG 338
           K    D AP +K    P+P   +    P +    EP P     P +T PK  +P+ ++  
Sbjct: 315 KTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSA 374

Query: 339 PPVPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPSQFEAPGPFSEQASLLDLDFDPL 398
           P  P  P  T +K             T   E + TTP +  AP    E A          
Sbjct: 375 PTTPKEPAPTTTKSAPTTP--KEPAPTTTKEPAPTTPKE-PAPTTTKEPAPTTTKSAPTT 431

Query: 399 P----PVTSPVKAPTPSGQSIPWDLWEPTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPG 454
           P    P T    APT   +  P    EPT +            A  T     P+   +P 
Sbjct: 432 PKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPA 491

Query: 455 PAQPAEASEVAGGTQPAAGAQEPGETAASEAA---SSSLPAVVVETFPAT 501
           P  P E +            +EP  T   E A   + S P    E  P T
Sbjct: 492 PTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTT 541



 Score = 50.4 bits (119), Expect = 4e-06
 Identities = 63/251 (25%), Positives = 85/251 (33%), Gaps = 32/251 (12%)

Query: 285 PSDNAPAKGNKSPSPPDGSPAAT----PEIRVNHEPEPAGGATPGATLPKSPSQLRKGPP 340
           P + AP     +P+ P   PA T    P      EP P     P  T  K PS      P
Sbjct: 464 PKEPAPTTKEPAPTTPK-EPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEP 522

Query: 341 VPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTT-----PSQFEAPGPFSEQASLLDLDF 395
            P   K  P+   +     +    T   E S TT     P+  + P P + +        
Sbjct: 523 APTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPK 582

Query: 396 DPLPPVTSPVKAPTPSGQSIPWDLWEPT-ESPAGSLPSGEPSAAEGTFAVSWPSQTAEPG 454
           +P  P T    APT + +  P    EP   +P  + P+        T     P+   +P 
Sbjct: 583 EP-APTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPA 641

Query: 455 PAQPAEAS------------EVAGGTQPAAGA----QEPGETAASEAASSS----LPAVV 494
           P  P E +            E    T P A A    +EP  T   E A ++     P   
Sbjct: 642 PTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTP 701

Query: 495 VETFPATVNGT 505
            ET P T  GT
Sbjct: 702 KETAPTTPKGT 712



 Score = 50.1 bits (118), Expect = 6e-06
 Identities = 58/230 (25%), Positives = 81/230 (35%), Gaps = 25/230 (10%)

Query: 280 TVKAQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGP 339
           T   +P+         +P  P  +    P      EP P     P  T PK P+   K P
Sbjct: 415 TTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEP 474

Query: 340 PVPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPSQFEAPGPFSEQASLLDLDFDPLP 399
               P +  P+   K          T   E + TTP +   P P + +        +P P
Sbjct: 475 APTTPKEPAPTAPKKP-------APTTPKEPAPTTPKE---PAPTTTKEPSPTTPKEPAP 524

Query: 400 ------PVTSPVKAPTPSGQSIPWDLWEP----TESPAGSLPSGEPSAAEGTFAVSWPSQ 449
                 P T+   APT + +S P    EP    T+ PA + P  EP  A  T     P+ 
Sbjct: 525 TTTKSAPTTTKEPAPTTT-KSAPTTPKEPSPTTTKEPAPTTPK-EP--APTTPKKPAPTT 580

Query: 450 TAEPGPAQPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFP 499
             EP P  P E +            +EP  T   E A ++ P  +  T P
Sbjct: 581 PKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTT-PKKLTPTTP 629



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 60/227 (26%), Positives = 80/227 (35%), Gaps = 35/227 (15%)

Query: 280 TVKAQPS---DNAPAKGNKSPSPP-DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQL 335
           T K+ P+   + AP     +P+ P + SP  T E       EPA   TP    P +P + 
Sbjct: 526 TTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAP-TTPKKPAPTTPKEP 584

Query: 336 RKGPPVPPPPKHT--PSKEVKQEQILSLFEDTFVPEISVTTPSQFEAPGPFSEQASLLDL 393
               P  P P  T  P+    +E        T   E + TTP +     P          
Sbjct: 585 APTTPKEPAPTTTKKPAPTTPKEP-----APTTPKETAPTTPKKLTPTTP---------- 629

Query: 394 DFDPLPPVTSPVKAPTPSGQSIPWDLWEPT-ESPAGSLPSGEPSAAEGTFAVSWPSQTAE 452
             + L P T    APT   +  P    EPT  +P    P+   +AA  T     P+   E
Sbjct: 630 --EKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKE 687

Query: 453 PGPAQPAE---------ASEVAGGTQPAAGAQEPGETAASEAASSSL 490
           P P  P E         A     GT P    +EP  T   + A   L
Sbjct: 688 PAPTTPKEPAPTTPKETAPTTPKGTAPTT-LKEPAPTTPKKPAPKEL 733



 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 58/242 (23%), Positives = 82/242 (33%), Gaps = 24/242 (9%)

Query: 285 PSDNAPAKGNKSPSPP-DGSPAAT--PEIRVNHEPEPAGGATP-------GATLPKSPSQ 334
           P + AP     +P+ P + +P  T  P      EP P     P         T PK P+ 
Sbjct: 378 PKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAP 437

Query: 335 LRKGPPVPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPSQFEAPGPFSEQASLLDLD 394
                P P  PK       K+    +  E    P      P+  + P P + +       
Sbjct: 438 TTPKKPAPTTPKEPAPTTPKEPTPTTPKEP--APTTKEPAPTTPKEPAPTAPKKPAPTTP 495

Query: 395 FDPLPPVTSPVKAPTPSGQSIPWDLWEPTESPAGSLP--SGEPS-----AAEGTFAVSWP 447
            +P  P T    APT + +  P    EP  +   S P  + EP+     +A  T     P
Sbjct: 496 KEP-APTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSP 554

Query: 448 SQTAEPGPAQPAEASEVAGGTQPAAGAQEPGETAASEAASSS----LPAVVVETFPATVN 503
           + T EP P  P E +            +EP  T   E A ++     P    E  P T  
Sbjct: 555 TTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPK 614

Query: 504 GT 505
            T
Sbjct: 615 ET 616



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 56/238 (23%), Positives = 84/238 (35%), Gaps = 32/238 (13%)

Query: 280 TVKAQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGP 339
           T   +P+   P +   +P+ P  +   TP+     EP P     P  T PK P+      
Sbjct: 651 TTPEEPTPTTPEE--PAPTTPKAAAPNTPK-----EPAPTTPKEPAPTTPKEPAPTTPKE 703

Query: 340 PVPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPSQ-----FEAPGPFSEQASLLDLD 394
             P  PK T    +K E   +  +     E++ TT  +      + P P + + +     
Sbjct: 704 TAPTTPKGTAPTTLK-EPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTP 762

Query: 395 FDPLPPVTSPVKAPTPSGQSIPWDLWEPTESP---------AGSLPSGEPSAAEGTFAVS 445
            +P  P T    APT    + P  L EP  +          A +   G  S      A +
Sbjct: 763 KEP-APTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPT 821

Query: 446 WPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVN 503
            P +TA   P +PA        T P   A    ET     +  S P    E  P T++
Sbjct: 822 TPKETAPTTPKEPAP-------TTPKKPAPTTPETPPPTTSEVSTPTTTKE--PTTIH 870



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 58/231 (25%), Positives = 78/231 (33%), Gaps = 17/231 (7%)

Query: 296 SPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPPPKHTPSKEVKQ 355
           +P+ P G+   TP+     EP P     P  T PK  +      P P  PK    KE+  
Sbjct: 750 APTTPKGTAPTTPK-----EPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAP 804

Query: 356 EQILSLFEDTFVPEISVTTPSQFEAPGPFSEQASLLDLDFDPLPPVTSPVKAPTPSGQSI 415
                    T   + + TTP +  AP    E A        P  P T P   PT S  S 
Sbjct: 805 TTTKGP-TSTTSDKPAPTTPKE-TAPTTPKEPAPTTPKKPAPTTPETPP---PTTSEVST 859

Query: 416 PWDLWEPT---ESPAGSLP--SGEPS--AAEGTFAVSWPSQTAEPGPAQPAEASEVAGGT 468
           P    EPT   +SP  S P  S EP+  A E +        T  P   +P   +     T
Sbjct: 860 PTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKT 919

Query: 469 QPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPP 519
                   P  T A+   +        +T  + +  T    +     D  P
Sbjct: 920 TERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTP 970



 Score = 30.0 bits (66), Expect = 6.3
 Identities = 26/107 (24%), Positives = 38/107 (35%), Gaps = 6/107 (5%)

Query: 278 TFTVKAQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRK 337
           T    A  +   PA    +P+   G  + T +      P+     TP    P +P +   
Sbjct: 785 TLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAP 844

Query: 338 GPPVPPPPK----HTPSKEVKQEQILSLFEDTFVPEISV-TTPSQFE 379
             P  PPP      TP+   K+   +    D   PE+S   TP   E
Sbjct: 845 TTPETPPPTTSEVSTPT-TTKEPTTIHKSPDESTPELSAEPTPKALE 890


>gi|47132519 Ras association and pleckstrin homology domains 1 isoform
            1 [Homo sapiens]
          Length = 1250

 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 58/221 (26%), Positives = 68/221 (30%), Gaps = 37/221 (16%)

Query: 297  PSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVP-------------- 342
            P PP     A P   +   P       P  TLPK  S   K PP P              
Sbjct: 809  PVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQ 868

Query: 343  -PPPKHTPSKEVKQEQILSLFEDTFVPEISVTT-------PSQFEAPGP-FSEQASLLDL 393
             PPP   P+ E    Q L        P+            PS    P P F        L
Sbjct: 869  FPPPPTPPAME---SQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSL 925

Query: 394  DFDP--------LPPVTSPVKAPTPSGQSIPWDLWEPTESPAGSLPSGEPSAAEGTFAVS 445
             F P         PP   P  +PTP     P      T SP G  P   P   +   ++ 
Sbjct: 926  VFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKP---PPTPQRNSSIK 982

Query: 446  WPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGETAASEAA 486
              S    P P +P+  S V+  T PA       ET    AA
Sbjct: 983  SSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAA 1023



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 62/256 (24%), Positives = 80/256 (31%), Gaps = 56/256 (21%)

Query: 248 LEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPPDGSPAAT 307
           LEE+    M  +N+    ++  L  Q    T    +QPS   P      P PP   P   
Sbjct: 587 LEESSKARMESMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPP 646

Query: 308 PEIRVNHEPEPAGGATP------------------GA-----TLPKSPSQLRK------- 337
           P +     P  AG A P                  GA     T P   SQ  K       
Sbjct: 647 PPLPSQSAPS-AGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPP 705

Query: 338 ----GPPVPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPSQFEAPGP--FSEQASLL 391
                PP PPPP  TP   + Q            P     +  QF AP P     Q   +
Sbjct: 706 NGVVPPPPPPPPPPTPGSAMAQ----------LKPAPCAPSLPQFSAPPPPLKIHQVQHI 755

Query: 392 DLDFDPLPPVTSPVKAPTPSGQ------SIPWDLWEPTESPA---GSLPSGEPSAAEGTF 442
                P PP   P+ AP P         +IP      T +P     + P+  P       
Sbjct: 756 TQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKK 815

Query: 443 AVSWPSQTAEPGPAQP 458
             ++P+    P P  P
Sbjct: 816 QPAFPASYIPPSPPTP 831



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 59/233 (25%), Positives = 87/233 (37%), Gaps = 29/233 (12%)

Query: 284 QPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPP 343
           +P    PA  +     P  + AA P       P     A P + +P SP      PPVP 
Sbjct: 780 KPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPT----PPVPV 835

Query: 344 PPKHTPSKEVKQEQILSLFED---TFVPEISVTTPSQFEAPGPFSEQASLLDLDFDPLPP 400
           PP   P    KQ+   +       + VP +     SQF  P P +  A    ++  PL P
Sbjct: 836 PPPTLP----KQQSFCAKPPPSPLSPVPSVVKQIASQF--PPPPTPPA----MESQPLKP 885

Query: 401 VTSPVKAPTPSGQSIPWDLWEPTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAE 460
           V + V   +P         W+P+  P  S P   P   E +    +P     P PA P  
Sbjct: 886 VPANVAPQSPPAVKAK-PKWQPSSIPVPS-PDFPPPPPESSLV--FPPPPPSPVPAPPPP 941

Query: 461 ASEVAGGTQPAAGAQEPG-ETAASEAASSSLPAVVVETFPATVNGTVEGGSGA 512
               A  T   +G+  PG +T+ + +     P    +      N +++  SGA
Sbjct: 942 PPPTASPTPDKSGS--PGKKTSKTSSPGGKKPPPTPQR-----NSSIKSSSGA 987



 Score = 33.1 bits (74), Expect = 0.74
 Identities = 52/222 (23%), Positives = 75/222 (33%), Gaps = 40/222 (18%)

Query: 281  VKAQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPP 340
            +K  P++ AP       + P   P++ P    +  P P   +      P  P      PP
Sbjct: 883  LKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESS---LVFPPPPPSPVPAPP 939

Query: 341  VPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPSQFEAPG-PFSEQASLLDLDFDPLP 399
             PPPP  +P                        TP +  +PG   S+ +S       P P
Sbjct: 940  PPPPPTASP------------------------TPDKSGSPGKKTSKTSSPGGKKPPPTP 975

Query: 400  PVTSPVKAPTPSGQSIPWDLWEPTESPAGSLPSG-EPSAAEGTFAVSWPSQTAEPGPAQP 458
               S +K  + SG   P    EP      SL S   P A  G+     PS+   P PA P
Sbjct: 976  QRNSSIK--SSSGAEHP----EPKRPSVDSLVSKFTPPAESGS-----PSKETLPPPAAP 1024

Query: 459  AEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPA 500
             +  ++        G  + G  +A     S      V  FP+
Sbjct: 1025 PKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFPS 1066


>gi|112734870 hypothetical protein LOC57648 [Homo sapiens]
          Length = 1094

 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 55/201 (27%), Positives = 77/201 (38%), Gaps = 29/201 (14%)

Query: 290 PAKGNKSPSPPD---GSPAATPEIRVNHEPEPAGGATPGATLP---KSP--SQLRKGPPV 341
           P    +SP+P      +PA  P      +  P    TP  TL    +SP  S+ +  PP 
Sbjct: 673 PPSKPRSPNPAAPALAAPAVVPGPVSTTDASPQSPPTPQTTLTPLQESPVISKDQSPPPS 732

Query: 342 PPPPKHTPSKEVKQ-EQILSLFEDTFVPEISVTTPSQFEAPGPFSEQASLLDLDFDPLPP 400
           PPP  H P    K+ E ++     +   E  +  P+    P P  E+  L   DF P   
Sbjct: 733 PPPSYHPPPPPTKKPEVVVEAPSASETAEEPLQDPNWPPPPPPAPEEQDLSMADFPPPEE 792

Query: 401 VTSPVKAPTPSGQSIPWDLWEPTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAE 460
               V +P P+G S   +L     SPA        S++  T     P  + +P PA PA 
Sbjct: 793 AFFSVASPEPAGPSGSPEL---VSSPAA-------SSSSATALQIQPPGSPDPPPAPPA- 841

Query: 461 ASEVAGGTQPAAGAQEPGETA 481
                    PA  +  PG  A
Sbjct: 842 ---------PAPASSAPGHVA 853



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 52/228 (22%), Positives = 81/228 (35%), Gaps = 37/228 (16%)

Query: 297 PSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPPPKHTPSKEVKQE 356
           P P   +P + P  +    P PA  A     +   P       P  PP   T    +++ 
Sbjct: 662 PHPKVPAPFSPPPSKPR-SPNPAAPALAAPAVVPGPVSTTDASPQSPPTPQTTLTPLQES 720

Query: 357 QILSLFED---------------TFVPEISVTTPSQFEAPGPFSEQASLLDLDFDPLPPV 401
            ++S  +                T  PE+ V  PS  E     + +  L D ++ P PP 
Sbjct: 721 PVISKDQSPPPSPPPSYHPPPPPTKKPEVVVEAPSASE-----TAEEPLQDPNWPPPPP- 774

Query: 402 TSPVKAPTPSGQSIPWDLWEPTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEA 461
                 P P  Q +    + P E    S+ S EP+   G+     P   + P     + +
Sbjct: 775 ------PAPEEQDLSMADFPPPEEAFFSVASPEPAGPSGS-----PELVSSPA---ASSS 820

Query: 462 SEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGG 509
           S  A   QP  G+ +P     + A +SS P  V +       G  +GG
Sbjct: 821 SATALQIQP-PGSPDPPPAPPAPAPASSAPGHVAKLPQKEPVGCSKGG 867



 Score = 39.3 bits (90), Expect = 0.010
 Identities = 60/229 (26%), Positives = 78/229 (34%), Gaps = 44/229 (19%)

Query: 282 KAQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPV 341
           + QP +++ A  +  P P  GS   +P      E            L      LRK    
Sbjct: 439 EGQP-ESSTASNSVVPPPQGGSGRGSPSGGSTAEASDTLSIRSSGQLSGRSVSLRKLKRP 497

Query: 342 PPPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPSQFEAPGPFSEQASLLDLDFDPLPPV 401
           PPPP+ T S   +            VP+  +  P     P P  +Q   L     P PP 
Sbjct: 498 PPPPRRTHSLHQR---------GLAVPDGPLGLP-----PKPERKQQPQL-----PRPPT 538

Query: 402 TSPVK----APTPSGQSIPWDLWEPTESPAGS-----------LPSGEPSAAEGTFAV-- 444
           T   +    AP P     P + W P  SP GS            PS   S+  GT  +  
Sbjct: 539 TGGSEGAGAAPCPPN---PANSWVPGLSPGGSRRPPRSPERTLSPSSGYSSQSGTPTLPP 595

Query: 445 -SWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPA 492
                  A PG AQP +   V     P A       +  S  +SSS PA
Sbjct: 596 KGLAGPPASPGKAQPPKPERVTSLRSPGASV---SSSLTSLCSSSSDPA 641



 Score = 38.9 bits (89), Expect = 0.013
 Identities = 59/248 (23%), Positives = 82/248 (33%), Gaps = 52/248 (20%)

Query: 285 PSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPP 344
           P   +P        PP   P+  P      +PE    A   +   + P Q    PP PPP
Sbjct: 716 PLQESPVISKDQSPPPSPPPSYHPPPPPTKKPEVVVEAPSASETAEEPLQDPNWPPPPPP 775

Query: 345 PKHTPSKEVKQEQILSLF-----EDTFV------PEISVTTPSQFEAPGPFSEQASLLDL 393
                     +EQ LS+      E+ F       P     +P    +P   S  A+ L +
Sbjct: 776 --------APEEQDLSMADFPPPEEAFFSVASPEPAGPSGSPELVSSPAASSSSATALQI 827

Query: 394 ------DFDPLPPVTSPVKAPTPSGQSIPW---------------DLWEPTESP------ 426
                 D  P PP  +P  +       +P                D+  P  +P      
Sbjct: 828 QPPGSPDPPPAPPAPAPASSAPGHVAKLPQKEPVGCSKGGGPPREDVGAPLVTPSLLQMV 887

Query: 427 ---AGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGETAAS 483
              +   P G P+ A G  A   P + A  G A P  A   + G   AA   +    AAS
Sbjct: 888 RLRSVGAPGGAPTPALGPSAPQKPLRRALSGRASPVPAP--SSGLH-AAVRLKACSLAAS 944

Query: 484 EAASSSLP 491
           E  SS+ P
Sbjct: 945 EGLSSAQP 952


>gi|116284392 mucin 2 precursor [Homo sapiens]
          Length = 5179

 Score = 50.4 bits (119), Expect = 4e-06
 Identities = 51/196 (26%), Positives = 65/196 (33%), Gaps = 27/196 (13%)

Query: 278  TFTVKAQPSDNAPAKGNKSPSPPDGS-----PAATPEIRVNHEPEPAGGAT---PGATLP 329
            T T    P+         +PSPP  +     P  TP       P P    T   P  T P
Sbjct: 1622 TTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTP 1681

Query: 330  KSPSQLRKGPPVP----PPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPSQFEAPGPFS 385
             SP      PP      P P  TPS  +      S       P  ++TTPS    P P +
Sbjct: 1682 SSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPT 1741

Query: 386  EQASLL-------DLDFDPLPP-VTSPVKAP----TPSGQSIP---WDLWEPTESPAGSL 430
               + L        L   PLPP +T P  +P    TP+   +P   W  W  +  P    
Sbjct: 1742 TTMTTLPPTTTSSPLTTTPLPPSITPPTFSPFSTTTPTTPCVPLCNWTGWLDSGKPNFHK 1801

Query: 431  PSGEPSAAEGTFAVSW 446
            P G+           W
Sbjct: 1802 PGGDTELIGDVCGPGW 1817



 Score = 49.7 bits (117), Expect = 8e-06
 Identities = 65/287 (22%), Positives = 89/287 (31%), Gaps = 38/287 (13%)

Query: 241  TFQSIAGLEENF--------HKEMSKLNQNLN-DVLVGL----EKQHGSNTFTVKAQ--- 284
            TF  + G  E+         H  + +L Q +  DV VG     E Q G+  F +      
Sbjct: 1325 TFDGVCGAPEDIECRSVKDPHLSLEQLGQKVQCDVSVGFICKNEDQFGNGPFGLCYDYKI 1384

Query: 285  ------PSDNA---PAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQL 335
                  P D     P+    +PSPP  S    P       P       P  T P  P   
Sbjct: 1385 RVNCCWPMDKCITTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPIT- 1443

Query: 336  RKGPPVPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPS-QFEAPGPFSEQASLLDLD 394
                   PPP  TPS  +      +    T  P    TTPS     P P +   +     
Sbjct: 1444 ---TTTTPPPTTTPSPPI---STTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPT 1497

Query: 395  FDPLPPVTSPVKAPTPSGQSIPWDLWEPTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPG 454
              P PP T+P+  P  +    P     P  +   + P     +   T  ++ P+ T    
Sbjct: 1498 TTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLP 1557

Query: 455  PAQPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPAT 501
            P            T P      P  T      + S P +   T P T
Sbjct: 1558 PTTTPSPPPTTTTTPPPTTTPSPPTT-----TTPSPPTITTTTPPPT 1599



 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 49/227 (21%), Positives = 71/227 (31%), Gaps = 26/227 (11%)

Query: 278  TFTVKAQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRK 337
            T T    P+         +PSPP  +    P       P       P +T    P+    
Sbjct: 1504 TTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPS 1563

Query: 338  GPPVP---PPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPSQFEAPGPFSEQASLLDLD 394
             PP     PPP  TPS                 P I+ TTP     P P +   +     
Sbjct: 1564 PPPTTTTTPPPTTTPSPPTTTTPS--------PPTITTTTPPPTTTPSPPTTTTTTPPPT 1615

Query: 395  FDPLPPVTSPVKAPTPSGQSIPWDLWEPTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPG 454
              P PP T+P+  PT +           T  P  + PS  P+        + PS      
Sbjct: 1616 TTPSPPTTTPITPPTST-----------TTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTT 1664

Query: 455  PAQPAEASEVAGGT----QPAAGAQEPGETAASEAASSSLPAVVVET 497
            P+ P   +     T     P      P  T  +  + ++ P+  + T
Sbjct: 1665 PSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITT 1711



 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 53/230 (23%), Positives = 67/230 (29%), Gaps = 23/230 (10%)

Query: 278  TFTVKAQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRK 337
            T T    P+         +PSPP  +    P       P       P  T P  P     
Sbjct: 1403 TTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPISTTT 1462

Query: 338  GPP---VPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPSQFEAPGPFSEQASLLDLD 394
             PP    P PP  TPS                 P  + TTP     P P +         
Sbjct: 1463 TPPPTTTPSPPTTTPSPPTTTPS---------PPTTTTTTPPPTTTPSPPTTTPITPPAS 1513

Query: 395  FDPLPPVTSPVKAPTPSGQSIPWDLWEPTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPG 454
               LPP T+P   PT +  + P     PT +P  S P+  P     +     P+ T  P 
Sbjct: 1514 TTTLPPTTTP-SPPTTTTTTPP-----PTTTP--SPPTTTPITPPTSTTTLPPTTTPSPP 1565

Query: 455  PAQPAEASEVAGGTQPAAGAQEP---GETAASEAASSSLPAVVVETFPAT 501
            P            + P      P     T      + S P     T P T
Sbjct: 1566 PTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPT 1615



 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 44/189 (23%), Positives = 62/189 (32%), Gaps = 19/189 (10%)

Query: 278  TFTVKAQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRK 337
            T T    P+         +PSPP  +  + P I             P  T P  P+    
Sbjct: 1559 TTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTT--------TPPPTTTPSPPTTTTT 1610

Query: 338  GPP---VPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPSQFEAPGPFSEQASLLDLD 394
             PP    P PP  TP         L        P  + TTP     P P +       + 
Sbjct: 1611 TPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPIT 1670

Query: 395  FDPLPPVTSPVKAP---TPSGQSIPWDLWEPTESPAGSL-----PSGEPSAAEGTFAVSW 446
                PP T+   +P   TPS  +       PT +P+  +     PS   + +     ++ 
Sbjct: 1671 TTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTT 1730

Query: 447  PSQTAEPGP 455
            PS T  P P
Sbjct: 1731 PSPTTTPSP 1739



 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 47/185 (25%), Positives = 60/185 (32%), Gaps = 21/185 (11%)

Query: 278  TFTVKAQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRK 337
            T T    P    P+    +P  P  S    P       P       P  T P  P+    
Sbjct: 1606 TTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTP 1665

Query: 338  GPPV----PPPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPSQFEAPGPFSEQASLLDL 393
             PP+     PPP  TPS  +              P  ++TTPS    P       +    
Sbjct: 1666 SPPITTTTTPPPTTTPSSPIT--------TTPSPPTTTMTTPSPTTTPSSPITTTTTPSS 1717

Query: 394  DFDPLPP---VTSPVKAPTPSGQSIPWDLWEP--TESPAGSLPSGEPSAAEGTFAVSWPS 448
               P PP   +T+P    TPS  +       P  T SP  + P   PS    TF+   P 
Sbjct: 1718 TTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPPTTTSSPLTTTPL-PPSITPPTFS---PF 1773

Query: 449  QTAEP 453
             T  P
Sbjct: 1774 STTTP 1778


>gi|222418647 mucin 7, secreted precursor [Homo sapiens]
          Length = 377

 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 59/261 (22%), Positives = 95/261 (36%), Gaps = 45/261 (17%)

Query: 226 ELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHG-SNTFTVKAQ 284
           ++PS+        + T  ++  L +N     S+ N N +  +  L   +  +   T  A 
Sbjct: 110 QIPSVTFPSASTKITTLPNVTFLPQNATTISSRENVNTSSSVATLAPVNSPAPQDTTAAP 169

Query: 285 PSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATL--PKSPSQLRKGPPVP 342
           P+ +A      S S P  + AA P      +  P+  A P  T   P  P+     P   
Sbjct: 170 PTPSATTPAPPSSSAPPETTAAPPTPSATTQAPPSSSAPPETTAAPPTPPATTPAPPSSS 229

Query: 343 PPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPSQFEAPGPFSEQASLLDLDFDPLPPVT 402
            PP+ T +                 P  S TTP+      P S  A          PP T
Sbjct: 230 APPETTAAP----------------PTPSATTPA------PLSSSA----------PPET 257

Query: 403 SPVKAPTPSGQSIPWDLWEPTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEAS 462
           + V  PTPS  ++          P+ +    E +AA  T + + P+  + P P +   A 
Sbjct: 258 TAV-PPTPSATTL---------DPSSASAPPETTAAPPTPSATTPAPPSSPAPQETTAAP 307

Query: 463 EVAGGTQPAAGAQEPGETAAS 483
                + P   A +  ET+A+
Sbjct: 308 ITTPNSSPTTLAPDTSETSAA 328



 Score = 35.8 bits (81), Expect = 0.11
 Identities = 49/177 (27%), Positives = 66/177 (37%), Gaps = 32/177 (18%)

Query: 328 LPKSPSQLRKGPPVPPPPKHTPSKEVKQEQILS--LFEDTFVPEISVTTPSQFEAPGPFS 385
           LP SP+   K P    PPKH      K   +++  L   T +P  SVT PS         
Sbjct: 74  LPPSPNNPPKFPNPHQPPKHPD----KNSSVVNPTLVATTQIP--SVTFPSA-------- 119

Query: 386 EQASLLDLDFDPLPPVTS-PVKAPTPSGQSIPWDLWEPTESPAGSLPSGEPSAAEGTFAV 444
                       LP VT  P  A T S +    +    + S A   P   P+  + T A 
Sbjct: 120 ------STKITTLPNVTFLPQNATTISSR----ENVNTSSSVATLAPVNSPAPQDTTAAP 169

Query: 445 SWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPAT 501
             PS T    P+  A     A    P+A  Q P  ++A    +++ P     T PAT
Sbjct: 170 PTPSATTPAPPSSSAPPETTAAPPTPSATTQAPPSSSAPPETTAAPP-----TPPAT 221



 Score = 34.7 bits (78), Expect = 0.25
 Identities = 53/228 (23%), Positives = 77/228 (33%), Gaps = 24/228 (10%)

Query: 282 KAQPSDNAPAK---GNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKG 338
           K  PS N P K    ++ P  PD + +      V      A    P  T P + +++   
Sbjct: 73  KLPPSPNNPPKFPNPHQPPKHPDKNSSVVNPTLV------ATTQIPSVTFPSASTKITTL 126

Query: 339 PPVPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPSQFEAPGPFSEQ-----ASLLDL 393
           P V   P++  +   ++    S    T  P  S        AP   S       +S    
Sbjct: 127 PNVTFLPQNATTISSRENVNTSSSVATLAPVNSPAPQDTTAAPPTPSATTPAPPSSSAPP 186

Query: 394 DFDPLPPVTSPVKAPTPSGQSIPWDLWEPTESPAGS-LPSGEPSAAEGTFAVSWPSQTAE 452
           +    PP  S      PS  + P     P   PA +  P    +  E T A   PS T  
Sbjct: 187 ETTAAPPTPSATTQAPPSSSAPPETTAAPPTPPATTPAPPSSSAPPETTAAPPTPSATT- 245

Query: 453 PGPAQPAEASEV--------AGGTQPAAGAQEPGETAASEAASSSLPA 492
           P P   +   E         A    P++ +  P  TAA    S++ PA
Sbjct: 246 PAPLSSSAPPETTAVPPTPSATTLDPSSASAPPETTAAPPTPSATTPA 293


>gi|222418649 mucin 7, secreted precursor [Homo sapiens]
          Length = 377

 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 59/261 (22%), Positives = 95/261 (36%), Gaps = 45/261 (17%)

Query: 226 ELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHG-SNTFTVKAQ 284
           ++PS+        + T  ++  L +N     S+ N N +  +  L   +  +   T  A 
Sbjct: 110 QIPSVTFPSASTKITTLPNVTFLPQNATTISSRENVNTSSSVATLAPVNSPAPQDTTAAP 169

Query: 285 PSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATL--PKSPSQLRKGPPVP 342
           P+ +A      S S P  + AA P      +  P+  A P  T   P  P+     P   
Sbjct: 170 PTPSATTPAPPSSSAPPETTAAPPTPSATTQAPPSSSAPPETTAAPPTPPATTPAPPSSS 229

Query: 343 PPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPSQFEAPGPFSEQASLLDLDFDPLPPVT 402
            PP+ T +                 P  S TTP+      P S  A          PP T
Sbjct: 230 APPETTAAP----------------PTPSATTPA------PLSSSA----------PPET 257

Query: 403 SPVKAPTPSGQSIPWDLWEPTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEAS 462
           + V  PTPS  ++          P+ +    E +AA  T + + P+  + P P +   A 
Sbjct: 258 TAV-PPTPSATTL---------DPSSASAPPETTAAPPTPSATTPAPPSSPAPQETTAAP 307

Query: 463 EVAGGTQPAAGAQEPGETAAS 483
                + P   A +  ET+A+
Sbjct: 308 ITTPNSSPTTLAPDTSETSAA 328



 Score = 35.8 bits (81), Expect = 0.11
 Identities = 49/177 (27%), Positives = 66/177 (37%), Gaps = 32/177 (18%)

Query: 328 LPKSPSQLRKGPPVPPPPKHTPSKEVKQEQILS--LFEDTFVPEISVTTPSQFEAPGPFS 385
           LP SP+   K P    PPKH      K   +++  L   T +P  SVT PS         
Sbjct: 74  LPPSPNNPPKFPNPHQPPKHPD----KNSSVVNPTLVATTQIP--SVTFPSA-------- 119

Query: 386 EQASLLDLDFDPLPPVTS-PVKAPTPSGQSIPWDLWEPTESPAGSLPSGEPSAAEGTFAV 444
                       LP VT  P  A T S +    +    + S A   P   P+  + T A 
Sbjct: 120 ------STKITTLPNVTFLPQNATTISSR----ENVNTSSSVATLAPVNSPAPQDTTAAP 169

Query: 445 SWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPAT 501
             PS T    P+  A     A    P+A  Q P  ++A    +++ P     T PAT
Sbjct: 170 PTPSATTPAPPSSSAPPETTAAPPTPSATTQAPPSSSAPPETTAAPP-----TPPAT 221



 Score = 34.7 bits (78), Expect = 0.25
 Identities = 53/228 (23%), Positives = 77/228 (33%), Gaps = 24/228 (10%)

Query: 282 KAQPSDNAPAK---GNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKG 338
           K  PS N P K    ++ P  PD + +      V      A    P  T P + +++   
Sbjct: 73  KLPPSPNNPPKFPNPHQPPKHPDKNSSVVNPTLV------ATTQIPSVTFPSASTKITTL 126

Query: 339 PPVPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPSQFEAPGPFSEQ-----ASLLDL 393
           P V   P++  +   ++    S    T  P  S        AP   S       +S    
Sbjct: 127 PNVTFLPQNATTISSRENVNTSSSVATLAPVNSPAPQDTTAAPPTPSATTPAPPSSSAPP 186

Query: 394 DFDPLPPVTSPVKAPTPSGQSIPWDLWEPTESPAGS-LPSGEPSAAEGTFAVSWPSQTAE 452
           +    PP  S      PS  + P     P   PA +  P    +  E T A   PS T  
Sbjct: 187 ETTAAPPTPSATTQAPPSSSAPPETTAAPPTPPATTPAPPSSSAPPETTAAPPTPSATT- 245

Query: 453 PGPAQPAEASEV--------AGGTQPAAGAQEPGETAASEAASSSLPA 492
           P P   +   E         A    P++ +  P  TAA    S++ PA
Sbjct: 246 PAPLSSSAPPETTAVPPTPSATTLDPSSASAPPETTAAPPTPSATTPA 293


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.309    0.128    0.373 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,373,966
Number of Sequences: 37866
Number of extensions: 1669742
Number of successful extensions: 14903
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 141
Number of HSP's successfully gapped in prelim test: 1198
Number of HSP's that attempted gapping in prelim test: 9836
Number of HSP's gapped (non-prelim): 4491
length of query: 593
length of database: 18,247,518
effective HSP length: 108
effective length of query: 485
effective length of database: 14,157,990
effective search space: 6866625150
effective search space used: 6866625150
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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