BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|21361693 solute carrier family 6, member 15 isoform 2 [Homo sapiens] (289 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|21361693 solute carrier family 6, member 15 isoform 2 [Homo s... 591 e-169 gi|33354281 solute carrier family 6, member 15 isoform 1 [Homo s... 524 e-149 gi|58219014 solute carrier family 6, member 17 [Homo sapiens] 378 e-105 gi|226437581 solute carrier family 6, member 15 isoform 3 [Homo ... 310 7e-85 gi|11181770 solute carrier family 6, member 20 isoform 1 [Homo s... 249 3e-66 gi|12408638 solute carrier family 6, member 20 isoform 2 [Homo s... 248 3e-66 gi|51468073 solute carrier family 6, member 19 [Homo sapiens] 243 2e-64 gi|194018524 solute carrier family 6, member 18 [Homo sapiens] 242 2e-64 gi|55749589 solute carrier family 6, member 16 [Homo sapiens] 202 3e-52 gi|171184408 solute carrier family 6 (neurotransmitter transport... 191 8e-49 gi|171184406 solute carrier family 6 (neurotransmitter transport... 191 8e-49 gi|171184404 solute carrier family 6 (neurotransmitter transport... 191 8e-49 gi|5032097 solute carrier family 6 member 8 isoform 1 [Homo sapi... 189 2e-48 gi|218563756 solute carrier family 6 member 8 isoform 2 [Homo sa... 189 2e-48 gi|197276623 solute carrier family 6 (neurotransmitter transport... 183 1e-46 gi|54607094 solute carrier family 6 (neurotransmitter transporte... 183 1e-46 gi|6005715 solute carrier family 6 (amino acid transporter), mem... 182 2e-46 gi|4507043 solute carrier family 6 member 4 [Homo sapiens] 180 1e-45 gi|21361581 solute carrier family 6 (neurotransmitter transporte... 180 1e-45 gi|7657587 solute carrier family 6 (neurotransmitter transporter... 176 2e-44 gi|188528618 solute carrier family 6 (neurotransmitter transport... 175 4e-44 gi|134304856 solute carrier family 6, member 7 [Homo sapiens] 174 6e-44 gi|67782317 solute carrier family 6 member 9 isoform 3 [Homo sap... 169 3e-42 gi|67782315 solute carrier family 6 member 9 isoform 2 [Homo sap... 169 3e-42 gi|67782313 solute carrier family 6 member 9 isoform 1 [Homo sap... 169 3e-42 gi|92859670 solute carrier family 6 (neurotransmitter transporte... 169 3e-42 gi|4557046 solute carrier family 6 member 2 [Homo sapiens] 166 2e-41 gi|4507041 solute carrier family 6 (neurotransmitter transporter... 164 8e-41 gi|197276625 solute carrier family 6 (neurotransmitter transport... 148 6e-36 gi|218563758 solute carrier family 6 member 8 isoform 3 [Homo sa... 100 1e-21 >gi|21361693 solute carrier family 6, member 15 isoform 2 [Homo sapiens] Length = 289 Score = 591 bits (1523), Expect = e-169 Identities = 289/289 (100%), Positives = 289/289 (100%) Query: 1 MPKNSKVVKRELDDDVTESVKDLLSNEDAADDAFKTSELIVDGQEEKDTDVEEGSEVEDE 60 MPKNSKVVKRELDDDVTESVKDLLSNEDAADDAFKTSELIVDGQEEKDTDVEEGSEVEDE Sbjct: 1 MPKNSKVVKRELDDDVTESVKDLLSNEDAADDAFKTSELIVDGQEEKDTDVEEGSEVEDE 60 Query: 61 RPAWNSKLQYILAQVGFSVGLGNVWRFPYLCQKNGGGAYLLPYLILLMVIGIPLFFLELS 120 RPAWNSKLQYILAQVGFSVGLGNVWRFPYLCQKNGGGAYLLPYLILLMVIGIPLFFLELS Sbjct: 61 RPAWNSKLQYILAQVGFSVGLGNVWRFPYLCQKNGGGAYLLPYLILLMVIGIPLFFLELS 120 Query: 121 VGQRIRRGSIGVWNYISPKLGGIGFASCVVCYFVALYYNVIIGWSLFYFSQSFQQPLPWD 180 VGQRIRRGSIGVWNYISPKLGGIGFASCVVCYFVALYYNVIIGWSLFYFSQSFQQPLPWD Sbjct: 121 VGQRIRRGSIGVWNYISPKLGGIGFASCVVCYFVALYYNVIIGWSLFYFSQSFQQPLPWD 180 Query: 181 QCPLVKNASHTFVEPECEQSSATTYYWYREALNISSSISESGGLNWKMTICLLAAWVMVC 240 QCPLVKNASHTFVEPECEQSSATTYYWYREALNISSSISESGGLNWKMTICLLAAWVMVC Sbjct: 181 QCPLVKNASHTFVEPECEQSSATTYYWYREALNISSSISESGGLNWKMTICLLAAWVMVC 240 Query: 241 LAMIKGIQSSGKVSMLEPFLILLITISGFIPLSNSVTDFCGQITHNTSF 289 LAMIKGIQSSGKVSMLEPFLILLITISGFIPLSNSVTDFCGQITHNTSF Sbjct: 241 LAMIKGIQSSGKVSMLEPFLILLITISGFIPLSNSVTDFCGQITHNTSF 289 >gi|33354281 solute carrier family 6, member 15 isoform 1 [Homo sapiens] Length = 730 Score = 524 bits (1350), Expect = e-149 Identities = 258/279 (92%), Positives = 266/279 (95%), Gaps = 3/279 (1%) Query: 1 MPKNSKVVKRELDDDVTESVKDLLSNEDAADDAFKTSELIVDGQEEKDTDVEEGSEVEDE 60 MPKNSKVVKRELDDDVTESVKDLLSNEDAADDAFKTSELIVDGQEEKDTDVEEGSEVEDE Sbjct: 1 MPKNSKVVKRELDDDVTESVKDLLSNEDAADDAFKTSELIVDGQEEKDTDVEEGSEVEDE 60 Query: 61 RPAWNSKLQYILAQVGFSVGLGNVWRFPYLCQKNGGGAYLLPYLILLMVIGIPLFFLELS 120 RPAWNSKLQYILAQVGFSVGLGNVWRFPYLCQKNGGGAYLLPYLILLMVIGIPLFFLELS Sbjct: 61 RPAWNSKLQYILAQVGFSVGLGNVWRFPYLCQKNGGGAYLLPYLILLMVIGIPLFFLELS 120 Query: 121 VGQRIRRGSIGVWNYISPKLGGIGFASCVVCYFVALYYNVIIGWSLFYFSQSFQQPLPWD 180 VGQRIRRGSIGVWNYISPKLGGIGFASCVVCYFVALYYNVIIGWSLFYFSQSFQQPLPWD Sbjct: 121 VGQRIRRGSIGVWNYISPKLGGIGFASCVVCYFVALYYNVIIGWSLFYFSQSFQQPLPWD 180 Query: 181 QCPLVKNASHTFVEPECEQSSATTYYWYREALNISSSISESGGLNWKMTICLLAAWVMVC 240 QCPLVKNASHTFVEPECEQSSATTYYWYREALNISSSISESGGLNWKMTICLLAAWVMVC Sbjct: 181 QCPLVKNASHTFVEPECEQSSATTYYWYREALNISSSISESGGLNWKMTICLLAAWVMVC 240 Query: 241 LAMIKGIQSSGKV---SMLEPFLILLITISGFIPLSNSV 276 LAMIKGIQSSGK+ S L P+++L+ + L+ S+ Sbjct: 241 LAMIKGIQSSGKIIYFSSLFPYVVLICFLIRAFLLNGSI 279 >gi|58219014 solute carrier family 6, member 17 [Homo sapiens] Length = 727 Score = 378 bits (970), Expect = e-105 Identities = 188/267 (70%), Positives = 222/267 (83%), Gaps = 8/267 (2%) Query: 1 MPKNSKVVKRELDDD-VTESVKDLLSNEDAADDAFKTSELIVDGQEE-KDTDVEEGSEVE 58 MPKNSKV +RE + VTESV DLL+ E+ D +K S L V G+ K VEE + E Sbjct: 1 MPKNSKVTQREHSSEHVTESVADLLALEEPVD--YKQSVLNVAGEAGGKQKAVEEELDAE 58 Query: 59 DERPAWNSKLQYILAQVGFSVGLGNVWRFPYLCQKNGGGAYLLPYLILLMVIGIPLFFLE 118 D RPAWNSKLQYILAQ+GFSVGLGN+WRFPYLCQKNGGGAYL+PYL+LL++IGIPLFFLE Sbjct: 59 D-RPAWNSKLQYILAQIGFSVGLGNIWRFPYLCQKNGGGAYLVPYLVLLIIIGIPLFFLE 117 Query: 119 LSVGQRIRRGSIGVWNYISPKLGGIGFASCVVCYFVALYYNVIIGWSLFYFSQSFQQPLP 178 L+VGQRIRRGSIGVW+YI P+LGGIGF+SC+VC FV LYYNVIIGWS+FYF +SFQ PLP Sbjct: 118 LAVGQRIRRGSIGVWHYICPRLGGIGFSSCIVCLFVGLYYNVIIGWSIFYFFKSFQYPLP 177 Query: 179 WDQCPLVKNASHTFVEPECEQSSATTYYWYREALNISSSISESGGLNWKMTICLLAAWVM 238 W +CP+V+N S VE ECE+SSATTY+WYREAL+IS SISESGGLNWKMT+CLL AW + Sbjct: 178 WSECPVVRNGSVAVVEAECEKSSATTYFWYREALDISDSISESGGLNWKMTLCLLVAWSI 237 Query: 239 VCLAMIKGIQSSGKV---SMLEPFLIL 262 V +A++KGIQSSGKV S L P+++L Sbjct: 238 VGMAVVKGIQSSGKVMYFSSLFPYVVL 264 >gi|226437581 solute carrier family 6, member 15 isoform 3 [Homo sapiens] Length = 623 Score = 310 bits (795), Expect = 7e-85 Identities = 151/172 (87%), Positives = 159/172 (92%), Gaps = 3/172 (1%) Query: 108 MVIGIPLFFLELSVGQRIRRGSIGVWNYISPKLGGIGFASCVVCYFVALYYNVIIGWSLF 167 MVIGIPLFFLELSVGQRIRRGSIGVWNYISPKLGGIGFASCVVCYFVALYYNVIIGWSLF Sbjct: 1 MVIGIPLFFLELSVGQRIRRGSIGVWNYISPKLGGIGFASCVVCYFVALYYNVIIGWSLF 60 Query: 168 YFSQSFQQPLPWDQCPLVKNASHTFVEPECEQSSATTYYWYREALNISSSISESGGLNWK 227 YFSQSFQQPLPWDQCPLVKNASHTFVEPECEQSSATTYYWYREALNISSSISESGGLNWK Sbjct: 61 YFSQSFQQPLPWDQCPLVKNASHTFVEPECEQSSATTYYWYREALNISSSISESGGLNWK 120 Query: 228 MTICLLAAWVMVCLAMIKGIQSSGKV---SMLEPFLILLITISGFIPLSNSV 276 MTICLLAAWVMVCLAMIKGIQSSGK+ S L P+++L+ + L+ S+ Sbjct: 121 MTICLLAAWVMVCLAMIKGIQSSGKIIYFSSLFPYVVLICFLIRAFLLNGSI 172 >gi|11181770 solute carrier family 6, member 20 isoform 1 [Homo sapiens] Length = 592 Score = 249 bits (635), Expect = 3e-66 Identities = 110/211 (52%), Positives = 157/211 (74%), Gaps = 5/211 (2%) Query: 57 VEDERPAWNSKLQYILAQVGFSVGLGNVWRFPYLCQKNGGGAYLLPYLILLMVIGIPLFF 116 +E RP W + LQ++ A + ++VGLGNVWRFPYLCQ GGG++L+PY+I+L+V G+PL + Sbjct: 1 MEKARPLWANSLQFVFACISYAVGLGNVWRFPYLCQMYGGGSFLVPYIIMLIVEGMPLLY 60 Query: 117 LELSVGQRIRRGSIGVWNYISPKLGGIGFASCVVCYFVALYYNVIIGWSLFYFSQSFQQP 176 LEL+VGQR+R+GSIG W ISP L G+G AS VV +F+++YYNVI W+ +Y SFQ P Sbjct: 61 LELAVGQRMRQGSIGAWRTISPYLSGVGVASVVVSFFLSMYYNVINAWAFWYLFHSFQDP 120 Query: 177 LPWDQCPLVKNASHTFVEPECEQSSATTYYWYREALNISSSISESGGLNWKMTICLLAAW 236 LPW CPL N +HT + ECE++S+T Y+WYR+ LNIS S+ E+GG+ W+ +CLL AW Sbjct: 121 LPWSVCPL--NGNHTGYDEECEKASSTQYFWYRKTLNISPSLQENGGVQWEPALCLLLAW 178 Query: 237 VMVCLAMIKGIQSSGKVSMLE---PFLILLI 264 ++V L +++G +S+GKV P+ +L+I Sbjct: 179 LVVYLCILRGTESTGKVVYFTASLPYCVLII 209 >gi|12408638 solute carrier family 6, member 20 isoform 2 [Homo sapiens] Length = 555 Score = 248 bits (634), Expect = 3e-66 Identities = 107/200 (53%), Positives = 152/200 (76%), Gaps = 2/200 (1%) Query: 57 VEDERPAWNSKLQYILAQVGFSVGLGNVWRFPYLCQKNGGGAYLLPYLILLMVIGIPLFF 116 +E RP W + LQ++ A + ++VGLGNVWRFPYLCQ GGG++L+PY+I+L+V G+PL + Sbjct: 1 MEKARPLWANSLQFVFACISYAVGLGNVWRFPYLCQMYGGGSFLVPYIIMLIVEGMPLLY 60 Query: 117 LELSVGQRIRRGSIGVWNYISPKLGGIGFASCVVCYFVALYYNVIIGWSLFYFSQSFQQP 176 LEL+VGQR+R+GSIG W ISP L G+G AS VV +F+++YYNVI W+ +Y SFQ P Sbjct: 61 LELAVGQRMRQGSIGAWRTISPYLSGVGVASVVVSFFLSMYYNVINAWAFWYLFHSFQDP 120 Query: 177 LPWDQCPLVKNASHTFVEPECEQSSATTYYWYREALNISSSISESGGLNWKMTICLLAAW 236 LPW CPL N +HT + ECE++S+T Y+WYR+ LNIS S+ E+GG+ W+ +CLL AW Sbjct: 121 LPWSVCPL--NGNHTGYDEECEKASSTQYFWYRKTLNISPSLQENGGVQWEPALCLLLAW 178 Query: 237 VMVCLAMIKGIQSSGKVSML 256 ++V L +++G +S+GK+ L Sbjct: 179 LVVYLCILRGTESTGKIEQL 198 >gi|51468073 solute carrier family 6, member 19 [Homo sapiens] Length = 634 Score = 243 bits (619), Expect = 2e-64 Identities = 112/236 (47%), Positives = 158/236 (66%), Gaps = 5/236 (2%) Query: 56 EVEDERPAWNSKLQYILAQVGFSVGLGNVWRFPYLCQKNGGGAYLLPYLILLMVIGIPLF 115 E RP W++K QY+L +GF VGLGNVWRFPYLCQ +GGGA+++P+LILL++ GIPL Sbjct: 27 EEASSRPKWDNKAQYMLTCLGFCVGLGNVWRFPYLCQSHGGGAFMIPFLILLVLEGIPLL 86 Query: 116 FLELSVGQRIRRGSIGVWNYISPKLGGIGFASCVVCYFVALYYNVIIGWSLFYFSQSFQQ 175 +LE ++GQR+RRGS+GVW+ I P L G+G AS + + V LYYN II W ++Y SFQ+ Sbjct: 87 YLEFAIGQRLRRGSLGVWSSIHPALKGLGLASMLTSFMVGLYYNTIISWIMWYLFNSFQE 146 Query: 176 PLPWDQCPLVKNASHTFVEPECEQSSATTYYWYREALNISSSISESGGLNWKMTICLLAA 235 PLPW CPL N + T EC +SS Y+WYRE LNIS+SIS+SG + W M +CL A Sbjct: 147 PLPWSDCPL--NENQTGYVDECARSSPVDYFWYRETLNISTSISDSGSIQWWMLLCLACA 204 Query: 236 WVMVCLAMIKGIQSSGK---VSMLEPFLILLITISGFIPLSNSVTDFCGQITHNTS 288 W ++ + I+GI+++GK ++ P+++L I + + L + T N + Sbjct: 205 WSVLYMCTIRGIETTGKAVYITSTLPYVVLTIFLIRGLTLKGATNGIVFLFTPNVT 260 >gi|194018524 solute carrier family 6, member 18 [Homo sapiens] Length = 628 Score = 242 bits (618), Expect = 2e-64 Identities = 108/212 (50%), Positives = 156/212 (73%), Gaps = 5/212 (2%) Query: 56 EVEDERPAWNSKLQYILAQVGFSVGLGNVWRFPYLCQKNGGGAYLLPYLILLMVIGIPLF 115 ++ DERP W++K QY+L+ GF+VGLGN+WRFPYLCQ GGGA+L+PY+I L+ GIP+F Sbjct: 13 DLGDERPKWDNKAQYLLSCTGFAVGLGNIWRFPYLCQTYGGGAFLIPYVIALVFEGIPIF 72 Query: 116 FLELSVGQRIRRGSIGVWNYISPKLGGIGFASCVVCYFVALYYNVIIGWSLFYFSQSFQQ 175 +EL++GQR+R+GS+GVW ISP L G+G + + ++LYYN I+ W L+Y SFQ Sbjct: 73 HVELAIGQRLRKGSVGVWTAISPYLSGVGLGCVTLSFLISLYYNTIVAWVLWYLLNSFQH 132 Query: 176 PLPWDQCPLVKNASHTFVEPECEQSSATTYYWYREALNISSSISESGGLNWKMTICLLAA 235 PLPW CP N + FVE EC+ SSA +Y+WYR+ LNI++ I++SG + W + ICL A+ Sbjct: 133 PLPWSSCPPDLNRT-GFVE-ECQGSSAVSYFWYRQTLNITADINDSGSIQWWLLICLAAS 190 Query: 236 WVMVCLAMIKGIQSSGKV---SMLEPFLILLI 264 W +V + +I+GI+++GKV + L P+L+L I Sbjct: 191 WAVVYMCVIRGIETTGKVIYFTALFPYLVLTI 222 >gi|55749589 solute carrier family 6, member 16 [Homo sapiens] Length = 736 Score = 202 bits (514), Expect = 3e-52 Identities = 92/216 (42%), Positives = 142/216 (65%), Gaps = 2/216 (0%) Query: 55 SEVEDERPAWNSKLQYILAQVGFSVGLGNVWRFPYLCQKNGGGAYLLPYLILLMVIGIPL 114 SEV RP W+SK +YILAQVGFS+ +WRF YL +GG ++ Y+ +L ++G+PL Sbjct: 97 SEVLLARPFWSSKTEYILAQVGFSMKPSCLWRFAYLWLNSGGCSFAAIYIFMLFLVGVPL 156 Query: 115 FFLELSVGQRIRRGSIGVWNYISPKLGGIGFASCVVCYFVALYYNVIIGWSLFYFSQSFQ 174 FLE++ GQ +R+G +GVW I+P +GG+G++S +VC+ + LY+NV+ W +FY SQSFQ Sbjct: 157 LFLEMAAGQSMRQGGMGVWKIIAPWIGGVGYSSFMVCFILGLYFNVVNSWIIFYMSQSFQ 216 Query: 175 QPLPWDQCPLVKNASHTFVEPECEQSSATTYYWYREALNISSSISESGGLNWKMTICLLA 234 P+PW++CPL N+S +PECE+++ + Y+WY++AL S I + G + + + Sbjct: 217 FPVPWEKCPLTMNSSG--FDPECERTTPSIYFWYQQALKASDRIEDGGSPVYSLVLPFFL 274 Query: 235 AWVMVCLAMIKGIQSSGKVSMLEPFLILLITISGFI 270 W +V MI G++S+GKV + L I + FI Sbjct: 275 CWCLVGAFMINGLKSTGKVIYVLVLLPCFIIVGFFI 310 >gi|171184408 solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12 [Homo sapiens] Length = 614 Score = 191 bits (484), Expect = 8e-49 Identities = 95/236 (40%), Positives = 139/236 (58%), Gaps = 14/236 (5%) Query: 44 QEEKDTDVEEGSEVEDERPAWNSKLQYILAQVGFSVGLGNVWRFPYLCQKNGGGAYLLPY 103 +E + D E+ +V+D R W +K++++L+ G +GLGNVWRFPYLC KNGGGA+ +PY Sbjct: 20 EEGEKLDQEDEDQVKD-RGQWTNKMEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFIPY 78 Query: 104 LILLMVIGIPLFFLELSVGQRIRRGSIGVWNYISPKLGGIGFASCVVCYFVALYYNVIIG 163 I V GIP+FFLE+++GQ +GS+ W I P GIG AS V+ ++ +YY +I+ Sbjct: 79 FIFFFVCGIPVFFLEVALGQYTSQGSVTAWRKICPLFQGIGLASVVIESYLNVYYIIILA 138 Query: 164 WSLFYFSQSFQQPLPWDQCPLVKNASHT----------FVEPECEQSSATTYYWYREALN 213 W+LFY SF LPW C N H V P +S +W R L Sbjct: 139 WALFYLFSSFTSELPWTTCNNFWNTEHCTDFLNHSGAGTVTPFENFTSPVMEFWERRVLG 198 Query: 214 ISSSISESGGLNWKMTICLLAAWVMVCLAMIKGIQSSGKV---SMLEPFLILLITI 266 I+S I + G L W++ +CLL AWV+ + KG++S+GKV + P+L+L+I + Sbjct: 199 ITSGIHDLGSLRWELALCLLLAWVICYFCIWKGVKSTGKVVYFTATFPYLMLVILL 254 >gi|171184406 solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12 [Homo sapiens] Length = 614 Score = 191 bits (484), Expect = 8e-49 Identities = 95/236 (40%), Positives = 139/236 (58%), Gaps = 14/236 (5%) Query: 44 QEEKDTDVEEGSEVEDERPAWNSKLQYILAQVGFSVGLGNVWRFPYLCQKNGGGAYLLPY 103 +E + D E+ +V+D R W +K++++L+ G +GLGNVWRFPYLC KNGGGA+ +PY Sbjct: 20 EEGEKLDQEDEDQVKD-RGQWTNKMEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFIPY 78 Query: 104 LILLMVIGIPLFFLELSVGQRIRRGSIGVWNYISPKLGGIGFASCVVCYFVALYYNVIIG 163 I V GIP+FFLE+++GQ +GS+ W I P GIG AS V+ ++ +YY +I+ Sbjct: 79 FIFFFVCGIPVFFLEVALGQYTSQGSVTAWRKICPLFQGIGLASVVIESYLNVYYIIILA 138 Query: 164 WSLFYFSQSFQQPLPWDQCPLVKNASHT----------FVEPECEQSSATTYYWYREALN 213 W+LFY SF LPW C N H V P +S +W R L Sbjct: 139 WALFYLFSSFTSELPWTTCNNFWNTEHCTDFLNHSGAGTVTPFENFTSPVMEFWERRVLG 198 Query: 214 ISSSISESGGLNWKMTICLLAAWVMVCLAMIKGIQSSGKV---SMLEPFLILLITI 266 I+S I + G L W++ +CLL AWV+ + KG++S+GKV + P+L+L+I + Sbjct: 199 ITSGIHDLGSLRWELALCLLLAWVICYFCIWKGVKSTGKVVYFTATFPYLMLVILL 254 >gi|171184404 solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12 [Homo sapiens] Length = 614 Score = 191 bits (484), Expect = 8e-49 Identities = 95/236 (40%), Positives = 139/236 (58%), Gaps = 14/236 (5%) Query: 44 QEEKDTDVEEGSEVEDERPAWNSKLQYILAQVGFSVGLGNVWRFPYLCQKNGGGAYLLPY 103 +E + D E+ +V+D R W +K++++L+ G +GLGNVWRFPYLC KNGGGA+ +PY Sbjct: 20 EEGEKLDQEDEDQVKD-RGQWTNKMEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFIPY 78 Query: 104 LILLMVIGIPLFFLELSVGQRIRRGSIGVWNYISPKLGGIGFASCVVCYFVALYYNVIIG 163 I V GIP+FFLE+++GQ +GS+ W I P GIG AS V+ ++ +YY +I+ Sbjct: 79 FIFFFVCGIPVFFLEVALGQYTSQGSVTAWRKICPLFQGIGLASVVIESYLNVYYIIILA 138 Query: 164 WSLFYFSQSFQQPLPWDQCPLVKNASHT----------FVEPECEQSSATTYYWYREALN 213 W+LFY SF LPW C N H V P +S +W R L Sbjct: 139 WALFYLFSSFTSELPWTTCNNFWNTEHCTDFLNHSGAGTVTPFENFTSPVMEFWERRVLG 198 Query: 214 ISSSISESGGLNWKMTICLLAAWVMVCLAMIKGIQSSGKV---SMLEPFLILLITI 266 I+S I + G L W++ +CLL AWV+ + KG++S+GKV + P+L+L+I + Sbjct: 199 ITSGIHDLGSLRWELALCLLLAWVICYFCIWKGVKSTGKVVYFTATFPYLMLVILL 254 >gi|5032097 solute carrier family 6 member 8 isoform 1 [Homo sapiens] Length = 635 Score = 189 bits (481), Expect = 2e-48 Identities = 88/232 (37%), Positives = 139/232 (59%), Gaps = 33/232 (14%) Query: 61 RPAWNSKLQYILAQVGFSVGLGNVWRFPYLCQKNGGGAYLLPYLILLMVIGIPLFFLELS 120 R W ++ +I++ VGF+VGLGNVWRFPYLC KNGGG +L+PY+++ +V GIP+FFLE+S Sbjct: 52 RETWTRQMDFIMSCVGFAVGLGNVWRFPYLCYKNGGGVFLIPYVLIALVGGIPIFFLEIS 111 Query: 121 VGQRIRRGSIGVWNYISPKLGGIGFASCVVCYFVALYYNVIIGWSLFYFSQSFQQPLPWD 180 +GQ ++ GSI VWN I P G+G+AS V+ ++ YY +++ W +Y +SF LPW Sbjct: 112 LGQFMKAGSINVWN-ICPLFKGLGYASMVIVFYCNTYYIMVLAWGFYYLVKSFTTTLPWA 170 Query: 181 QCPLVKNASHTFVEPEC-----------------------EQSSATTYYWYREALNISSS 217 C HT+ P+C ++ S +W + L +S Sbjct: 171 TC------GHTWNTPDCVEIFRHEDCANASLANLTCDQLADRRSPVIEFWENKVLRLSGG 224 Query: 218 ISESGGLNWKMTICLLAAWVMVCLAMIKGIQSSGKV---SMLEPFLILLITI 266 + G LNW++T+CLLA WV+V + KG++S+GK+ + P+++L++ + Sbjct: 225 LEVPGALNWEVTLCLLACWVLVYFCVWKGVKSTGKIVYFTATFPYVVLVVLL 276 >gi|218563756 solute carrier family 6 member 8 isoform 2 [Homo sapiens] Length = 625 Score = 189 bits (481), Expect = 2e-48 Identities = 88/232 (37%), Positives = 139/232 (59%), Gaps = 33/232 (14%) Query: 61 RPAWNSKLQYILAQVGFSVGLGNVWRFPYLCQKNGGGAYLLPYLILLMVIGIPLFFLELS 120 R W ++ +I++ VGF+VGLGNVWRFPYLC KNGGG +L+PY+++ +V GIP+FFLE+S Sbjct: 52 RETWTRQMDFIMSCVGFAVGLGNVWRFPYLCYKNGGGVFLIPYVLIALVGGIPIFFLEIS 111 Query: 121 VGQRIRRGSIGVWNYISPKLGGIGFASCVVCYFVALYYNVIIGWSLFYFSQSFQQPLPWD 180 +GQ ++ GSI VWN I P G+G+AS V+ ++ YY +++ W +Y +SF LPW Sbjct: 112 LGQFMKAGSINVWN-ICPLFKGLGYASMVIVFYCNTYYIMVLAWGFYYLVKSFTTTLPWA 170 Query: 181 QCPLVKNASHTFVEPEC-----------------------EQSSATTYYWYREALNISSS 217 C HT+ P+C ++ S +W + L +S Sbjct: 171 TC------GHTWNTPDCVEIFRHEDCANASLANLTCDQLADRRSPVIEFWENKVLRLSGG 224 Query: 218 ISESGGLNWKMTICLLAAWVMVCLAMIKGIQSSGKV---SMLEPFLILLITI 266 + G LNW++T+CLLA WV+V + KG++S+GK+ + P+++L++ + Sbjct: 225 LEVPGALNWEVTLCLLACWVLVYFCVWKGVKSTGKIVYFTATFPYVVLVVLL 276 >gi|197276623 solute carrier family 6 (neurotransmitter transporter, taurine), member 6 isoform a [Homo sapiens] Length = 620 Score = 183 bits (465), Expect = 1e-46 Identities = 94/241 (39%), Positives = 135/241 (56%), Gaps = 34/241 (14%) Query: 54 GSEVEDE-------RPAWNSKLQYILAQVGFSVGLGNVWRFPYLCQKNGGGAYLLPYLIL 106 G+ EDE R W+SK+ ++L+ G VGLGNVWRFPYLC KNGGGA+L+PY I Sbjct: 27 GTRPEDEAEGKPPQREKWSSKIDFVLSVAGGFVGLGNVWRFPYLCYKNGGGAFLIPYFIF 86 Query: 107 LMVIGIPLFFLELSVGQRIRRGSIGVWNYISPKLGGIGFASCVVCYFVALYYNVIIGWSL 166 L G+P+FFLE+ +GQ G I W I P GIG+AS V+ + +YY VI+ W+ Sbjct: 87 LFGSGLPVFFLEIIIGQYTSEGGITCWEKICPLFSGIGYASVVIVSLLNVYYIVILAWAT 146 Query: 167 FYFSQSFQQPLPWDQCPLVKNASHTFVEPECEQS------------SATTY------YWY 208 +Y QSFQ+ LPW C +H++ P C + S+T + +W Sbjct: 147 YYLFQSFQKELPWAHC------NHSWNTPHCMEDTMRKNKSVWITISSTNFTSPVIEFWE 200 Query: 209 REALNISSSISESGGLNWKMTICLLAAWVMVCLAMIKGIQSSGKV---SMLEPFLILLIT 265 R L++S I G L W + +CLL W++ + KG++S+GKV + PF +LL+ Sbjct: 201 RNVLSLSPGIDHPGSLKWDLALCLLLVWLVCFFCIWKGVRSTGKVVYFTATFPFAMLLVL 260 Query: 266 I 266 + Sbjct: 261 L 261 >gi|54607094 solute carrier family 6 (neurotransmitter transporter, taurine), member 6 isoform a [Homo sapiens] Length = 620 Score = 183 bits (465), Expect = 1e-46 Identities = 94/241 (39%), Positives = 135/241 (56%), Gaps = 34/241 (14%) Query: 54 GSEVEDE-------RPAWNSKLQYILAQVGFSVGLGNVWRFPYLCQKNGGGAYLLPYLIL 106 G+ EDE R W+SK+ ++L+ G VGLGNVWRFPYLC KNGGGA+L+PY I Sbjct: 27 GTRPEDEAEGKPPQREKWSSKIDFVLSVAGGFVGLGNVWRFPYLCYKNGGGAFLIPYFIF 86 Query: 107 LMVIGIPLFFLELSVGQRIRRGSIGVWNYISPKLGGIGFASCVVCYFVALYYNVIIGWSL 166 L G+P+FFLE+ +GQ G I W I P GIG+AS V+ + +YY VI+ W+ Sbjct: 87 LFGSGLPVFFLEIIIGQYTSEGGITCWEKICPLFSGIGYASVVIVSLLNVYYIVILAWAT 146 Query: 167 FYFSQSFQQPLPWDQCPLVKNASHTFVEPECEQS------------SATTY------YWY 208 +Y QSFQ+ LPW C +H++ P C + S+T + +W Sbjct: 147 YYLFQSFQKELPWAHC------NHSWNTPHCMEDTMRKNKSVWITISSTNFTSPVIEFWE 200 Query: 209 REALNISSSISESGGLNWKMTICLLAAWVMVCLAMIKGIQSSGKV---SMLEPFLILLIT 265 R L++S I G L W + +CLL W++ + KG++S+GKV + PF +LL+ Sbjct: 201 RNVLSLSPGIDHPGSLKWDLALCLLLVWLVCFFCIWKGVRSTGKVVYFTATFPFAMLLVL 260 Query: 266 I 266 + Sbjct: 261 L 261 >gi|6005715 solute carrier family 6 (amino acid transporter), member 14 [Homo sapiens] Length = 642 Score = 182 bits (463), Expect = 2e-46 Identities = 104/273 (38%), Positives = 146/273 (53%), Gaps = 42/273 (15%) Query: 34 FKTSELIVDGQEEKDTDVEEGSEVEDERPAWNSKLQYILAQVGFSVGLGNVWRFPYLCQK 93 FK E ++ V E E +D R W+ K Y+L+ +G++VGLGNVWRFPYL Sbjct: 10 FKCREKEKVSASSENFHVGENDENQD-RGNWSKKSDYLLSMIGYAVGLGNVWRFPYLTYS 68 Query: 94 NGGGAYLLPYLILLMVIGIPLFFLELSVGQRIRRGSIGVWNYISPKLGGIGFASCVVCYF 153 NGGGA+L+PY I+L + G+PLFFLE S+GQ G + VW I P G+G ++ F Sbjct: 69 NGGGAFLIPYAIMLALAGLPLFFLECSLGQFASLGPVSVWR-ILPLFQGVGITMVLISIF 127 Query: 154 VALYYNVIIGWSLFYFSQSFQQPLPWDQCP--LVKNASHTFVEPECEQSSA--------- 202 V +YYNVII +SL+Y SFQ LPW C KN S + + C S+ Sbjct: 128 VTIYYNVIIAYSLYYMFASFQSELPWKNCSSWSDKNCSRSPIVTHCNVSTVNKGIQEIIQ 187 Query: 203 --------------------------TTYYWYREALNISSSISESGGLNWKMTICLLAAW 236 + YW + AL SS ++E+G + W + +CLL AW Sbjct: 188 MNKSWVDINNFTCINGSEIYQPGQLPSEQYWNKVALQRSSGMNETGVIVWYLALCLLLAW 247 Query: 237 VMVCLAMIKGIQSSGKV---SMLEPFLILLITI 266 ++V A+ KGI+SSGKV + L P+++LLI + Sbjct: 248 LIVGAALFKGIKSSGKVVYFTALFPYVVLLILL 280 >gi|4507043 solute carrier family 6 member 4 [Homo sapiens] Length = 630 Score = 180 bits (457), Expect = 1e-45 Identities = 82/221 (37%), Positives = 136/221 (61%), Gaps = 12/221 (5%) Query: 58 EDERPAWNSKLQYILAQVGFSVGLGNVWRFPYLCQKNGGGAYLLPYLILLMVIGIPLFFL 117 + ER W K+ ++L+ +G++V LGNVWRFPY+C +NGGGA+LLPY I+ + GIPLF++ Sbjct: 76 QGERETWGKKVDFLLSVIGYAVDLGNVWRFPYICYQNGGGAFLLPYTIMAIFGGIPLFYM 135 Query: 118 ELSVGQRIRRGSIGVWNYISPKLGGIGFASCVVCYFVALYYNVIIGWSLFYFSQSFQQPL 177 EL++GQ R G I +W I P GIG+A C++ +++A YYN I+ W+L+Y SF L Sbjct: 136 ELALGQYHRNGCISIWRKICPIFKGIGYAICIIAFYIASYYNTIMAWALYYLISSFTDQL 195 Query: 178 PWDQCP---LVKNASHTFVEPE----CEQSSATTYYWYREALNI--SSSISESGGLNWKM 228 PW C N ++ F E +S ++ R L I S + + GG++W++ Sbjct: 196 PWTSCKNSWNTGNCTNYFSEDNITWTLHSTSPAEEFYTRHVLQIHRSKGLQDLGGISWQL 255 Query: 229 TICLLAAWVMVCLAMIKGIQSSGKVSMLE---PFLILLITI 266 +C++ + ++ ++ KG+++SGKV + P++IL + + Sbjct: 256 ALCIMLIFTVIYFSIWKGVKTSGKVVWVTATFPYIILSVLL 296 >gi|21361581 solute carrier family 6 (neurotransmitter transporter, GABA), member 13 [Homo sapiens] Length = 602 Score = 180 bits (457), Expect = 1e-45 Identities = 86/219 (39%), Positives = 126/219 (57%), Gaps = 12/219 (5%) Query: 60 ERPAWNSKLQYILAQVGFSVGLGNVWRFPYLCQKNGGGAYLLPYLILLMVIGIPLFFLEL 119 ER WN+K++++L+ G +GLGNVWRFPYLC KNGGGA+ +PYL+ L GIP+F LE Sbjct: 31 ERGHWNNKMEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFIPYLVFLFTCGIPVFLLET 90 Query: 120 SVGQRIRRGSIGVWNYISPKLGGIGFASCVVCYFVALYYNVIIGWSLFYFSQSFQQPLPW 179 ++GQ +G + W I P GIG+AS ++ + +YY +++ W+LFY SF LPW Sbjct: 91 ALGQYTSQGGVTAWRKICPIFEGIGYASQMIVILLNVYYIIVLAWALFYLFSSFTIDLPW 150 Query: 180 DQCPLVKNASHTFVEPECEQS---------SATTYYWYREALNISSSISESGGLNWKMTI 230 C N H + S S +W R L IS I G L W++ + Sbjct: 151 GGCYHEWNTEHCMEFQKTNGSLNGTSENATSPVIEFWERRVLKISDGIQHLGALRWELAL 210 Query: 231 CLLAAWVMVCLAMIKGIQSSGKV---SMLEPFLILLITI 266 CLL AWV+ + KG++S+GKV + P+L+L++ + Sbjct: 211 CLLLAWVICYFCIWKGVKSTGKVVYFTATFPYLMLVVLL 249 >gi|7657587 solute carrier family 6 (neurotransmitter transporter, GABA), member 11 [Homo sapiens] Length = 632 Score = 176 bits (446), Expect = 2e-44 Identities = 87/224 (38%), Positives = 128/224 (57%), Gaps = 20/224 (8%) Query: 60 ERPAWNSKLQYILAQVGFSVGLGNVWRFPYLCQKNGGGAYLLPYLILLMVIGIPLFFLEL 119 ER WN+K++++L+ G +GLGNVWRFPYLC KNGGGA+L+PY++ + GIP+FFLE Sbjct: 49 ERGHWNNKVEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFLIPYVVFFICCGIPVFFLET 108 Query: 120 SVGQRIRRGSIGVWNYISPKLGGIGFASCVVCYFVALYYNVIIGWSLFYFSQSFQQPLPW 179 ++GQ G I W + P GIG+A+ V+ + +YY +I+ W++FY S F LPW Sbjct: 109 ALGQFTSEGGITCWRKVCPLFEGIGYATQVIEAHLNVYYIIILAWAIFYLSNCFTTELPW 168 Query: 180 DQCP--------------LVKNASHTFVEPECEQSSATTYYWYREALNISSSISESGGLN 225 C V N SH ++ +S +W L IS I G L Sbjct: 169 ATCGHEWNTENCVEFQKLNVSNYSHVSLQ---NATSPVMEFWEHRVLAISDGIEHIGNLR 225 Query: 226 WKMTICLLAAWVMVCLAMIKGIQSSGKVSMLE---PFLILLITI 266 W++ +CLLAAW + + KG +S+GKV + P+++LLI + Sbjct: 226 WELALCLLAAWTICYFCIWKGTKSTGKVVYVTATFPYIMLLILL 269 >gi|188528618 solute carrier family 6 (neurotransmitter transporter, GABA), member 1 [Homo sapiens] Length = 599 Score = 175 bits (444), Expect = 4e-44 Identities = 90/261 (34%), Positives = 142/261 (54%), Gaps = 10/261 (3%) Query: 35 KTSELIVDGQEEKDTDVEEGSEVED--ERPAWNSKLQYILAQVGFSVGLGNVWRFPYLCQ 92 + SE V + K V+ + D +R W + ++++ VG+++GLGNVWRFPYLC Sbjct: 16 EVSEAPVANDKPKTLVVKVQKKAADLPDRDTWKGRFDFLMSCVGYAIGLGNVWRFPYLCG 75 Query: 93 KNGGGAYLLPYLILLMVIGIPLFFLELSVGQRIRRGSIGVWNYISPKLGGIGFASCVVCY 152 KNGGGA+L+PY + L+ G+PLF LE S+GQ G +GVW ++P G+G A+ V+ + Sbjct: 76 KNGGGAFLIPYFLTLIFAGVPLFLLECSLGQYTSIGGLGVWK-LAPMFKGVGLAAAVLSF 134 Query: 153 FVALYYNVIIGWSLFYFSQSFQQPLPWDQCPLVKNASHTF----VEPECEQSSATTYYWY 208 ++ +YY VII W+++Y SF LPW QC N F + +SA +W Sbjct: 135 WLNIYYIVIISWAIYYLYNSFTTTLPWKQCDNPWNTDRCFSNYSMVNTTNMTSAVVEFWE 194 Query: 209 REALNISSSISESGGLNWKMTICLLAAWVMVCLAMIKGIQSSGKV---SMLEPFLILLIT 265 R ++ + + G + W + I L AW++V + KG+ +GKV S P+++L+I Sbjct: 195 RNMHQMTDGLDKPGQIRWPLAITLAIAWILVYFCIWKGVGWTGKVVYFSATYPYIMLIIL 254 Query: 266 ISGFIPLSNSVTDFCGQITHN 286 + L + IT N Sbjct: 255 FFRGVTLPGAKEGILFYITPN 275 >gi|134304856 solute carrier family 6, member 7 [Homo sapiens] Length = 636 Score = 174 bits (442), Expect = 6e-44 Identities = 97/248 (39%), Positives = 138/248 (55%), Gaps = 20/248 (8%) Query: 36 TSELIVDGQEEKDTDVEEGSEVEDERPAWNSKLQYILAQVGFSVGLGNVWRFPYLCQKNG 95 T +L++ ++ D D++ + R W KL ++L+ +G+ VGLGNVWRFPY NG Sbjct: 14 TPDLLMTPSDQGDVDLDV--DFAAHRGNWTGKLDFLLSCIGYCVGLGNVWRFPYRAYTNG 71 Query: 96 GGAYLLPYLILLMVIGIPLFFLELSVGQRIRRGSIGVWNYISPKLGGIGFASCVVCYFVA 155 GGA+L+PY ++L + GIPLFFLELS+GQ G + VW ISP G G A ++ VA Sbjct: 72 GGAFLVPYFLMLAICGIPLFFLELSLGQFSSLGPLAVWK-ISPLFKGAGAAMLLIVGLVA 130 Query: 156 LYYNVIIGWSLFYFSQSFQQPLPWDQCPLVKNASHTFVEPECEQS------------SAT 203 +YYN+II + LFY S LPW+ C N + S + Sbjct: 131 IYYNMIIAYVLFYLFASLTSDLPWEHCGNWWNTELCLEHRVSKDGNGALPLNLTCTVSPS 190 Query: 204 TYYWYREALNI--SSSISESGGLNWKMTICLLAAWVMVCLAMIKGIQSSGKV---SMLEP 258 YW R L+I S I G + W + +CLL AWV+V L ++KG++SSGKV + P Sbjct: 191 EEYWSRYVLHIQGSQGIGSPGEIRWNLCLCLLLAWVIVFLCILKGVKSSGKVVYFTATFP 250 Query: 259 FLILLITI 266 +LILL+ + Sbjct: 251 YLILLMLL 258 >gi|67782317 solute carrier family 6 member 9 isoform 3 [Homo sapiens] Length = 633 Score = 169 bits (428), Expect = 3e-42 Identities = 87/233 (37%), Positives = 131/233 (56%), Gaps = 30/233 (12%) Query: 60 ERPAWNSKLQYILAQVGFSVGLGNVWRFPYLCQKNGGGAYLLPYLILLMVIGIPLFFLEL 119 +R W ++++++L VG++VGLGNVWRFPYLC +NGGGA++ PY I+L+ GIPLFF+EL Sbjct: 26 KRGNWGNQIEFVLTSVGYAVGLGNVWRFPYLCYRNGGGAFMFPYFIMLIFCGIPLFFMEL 85 Query: 120 SVGQRIRRGSIGVWNYISPKLGGIGFASCVVCYFVALYYNVIIGWSLFYFSQSFQQPLPW 179 S GQ +G +GVW ISP G+G+ VV ++ +YYNV+I + +YF S LPW Sbjct: 86 SFGQFASQGCLGVWR-ISPMFKGVGYGMMVVSTYIGIYYNVVICIAFYYFFSSMTHVLPW 144 Query: 180 DQC-------------------------PLVKNASHTFVEPECEQSSATTYYWYREALNI 214 C L N SH + +++S + YW L + Sbjct: 145 AYCNNPWNTHDCAGVLDASNLTNGSRPAALPSNLSH-LLNHSLQRTSPSEEYWRLYVLKL 203 Query: 215 SSSISESGGLNWKMTICLLAAWVMVCLAMIKGIQSSGKV---SMLEPFLILLI 264 S I G + + CL +W++V L +I+G++SSGKV + P+++L I Sbjct: 204 SDDIGNFGEVRLPLLGCLGVSWLVVFLCLIRGVKSSGKVVYFTATFPYVVLTI 256 >gi|67782315 solute carrier family 6 member 9 isoform 2 [Homo sapiens] Length = 706 Score = 169 bits (428), Expect = 3e-42 Identities = 87/233 (37%), Positives = 131/233 (56%), Gaps = 30/233 (12%) Query: 60 ERPAWNSKLQYILAQVGFSVGLGNVWRFPYLCQKNGGGAYLLPYLILLMVIGIPLFFLEL 119 +R W ++++++L VG++VGLGNVWRFPYLC +NGGGA++ PY I+L+ GIPLFF+EL Sbjct: 99 KRGNWGNQIEFVLTSVGYAVGLGNVWRFPYLCYRNGGGAFMFPYFIMLIFCGIPLFFMEL 158 Query: 120 SVGQRIRRGSIGVWNYISPKLGGIGFASCVVCYFVALYYNVIIGWSLFYFSQSFQQPLPW 179 S GQ +G +GVW ISP G+G+ VV ++ +YYNV+I + +YF S LPW Sbjct: 159 SFGQFASQGCLGVWR-ISPMFKGVGYGMMVVSTYIGIYYNVVICIAFYYFFSSMTHVLPW 217 Query: 180 DQC-------------------------PLVKNASHTFVEPECEQSSATTYYWYREALNI 214 C L N SH + +++S + YW L + Sbjct: 218 AYCNNPWNTHDCAGVLDASNLTNGSRPAALPSNLSH-LLNHSLQRTSPSEEYWRLYVLKL 276 Query: 215 SSSISESGGLNWKMTICLLAAWVMVCLAMIKGIQSSGKV---SMLEPFLILLI 264 S I G + + CL +W++V L +I+G++SSGKV + P+++L I Sbjct: 277 SDDIGNFGEVRLPLLGCLGVSWLVVFLCLIRGVKSSGKVVYFTATFPYVVLTI 329 >gi|67782313 solute carrier family 6 member 9 isoform 1 [Homo sapiens] Length = 652 Score = 169 bits (428), Expect = 3e-42 Identities = 87/233 (37%), Positives = 131/233 (56%), Gaps = 30/233 (12%) Query: 60 ERPAWNSKLQYILAQVGFSVGLGNVWRFPYLCQKNGGGAYLLPYLILLMVIGIPLFFLEL 119 +R W ++++++L VG++VGLGNVWRFPYLC +NGGGA++ PY I+L+ GIPLFF+EL Sbjct: 45 KRGNWGNQIEFVLTSVGYAVGLGNVWRFPYLCYRNGGGAFMFPYFIMLIFCGIPLFFMEL 104 Query: 120 SVGQRIRRGSIGVWNYISPKLGGIGFASCVVCYFVALYYNVIIGWSLFYFSQSFQQPLPW 179 S GQ +G +GVW ISP G+G+ VV ++ +YYNV+I + +YF S LPW Sbjct: 105 SFGQFASQGCLGVWR-ISPMFKGVGYGMMVVSTYIGIYYNVVICIAFYYFFSSMTHVLPW 163 Query: 180 DQC-------------------------PLVKNASHTFVEPECEQSSATTYYWYREALNI 214 C L N SH + +++S + YW L + Sbjct: 164 AYCNNPWNTHDCAGVLDASNLTNGSRPAALPSNLSH-LLNHSLQRTSPSEEYWRLYVLKL 222 Query: 215 SSSISESGGLNWKMTICLLAAWVMVCLAMIKGIQSSGKV---SMLEPFLILLI 264 S I G + + CL +W++V L +I+G++SSGKV + P+++L I Sbjct: 223 SDDIGNFGEVRLPLLGCLGVSWLVVFLCLIRGVKSSGKVVYFTATFPYVVLTI 275 >gi|92859670 solute carrier family 6 (neurotransmitter transporter, glycine), member 5 [Homo sapiens] Length = 797 Score = 169 bits (428), Expect = 3e-42 Identities = 94/266 (35%), Positives = 140/266 (52%), Gaps = 55/266 (20%) Query: 49 TDVEEGSEVEDERPAWNSKLQYILAQVGFSVGLGNVWRFPYLCQKNGGGAYLLPYLILLM 108 T +E + R W+SKL +IL+ VG++VGLGNVWRFPYL +NGGGA+L+PYL++L Sbjct: 179 TQEDEQGDENKARGNWSSKLDFILSMVGYAVGLGNVWRFPYLAFQNGGGAFLIPYLMMLA 238 Query: 109 VIGIPLFFLELSVGQRIRRGSIGVWNYISPKLGGIGFASCVVCYFVALYYNVIIGWSLFY 168 + G+P+FFLE+S+GQ +G + VW I P L G G A ++ +A+YYNVII ++LFY Sbjct: 239 LAGLPIFFLEVSLGQFASQGPVSVWKAI-PALQGCGIAMLIISVLIAIYYNVIICYTLFY 297 Query: 169 FSQSFQQPLPWDQCPLVKNASHTFVEPECEQS---------------------------- 200 SF LPW C ++ + PEC+ Sbjct: 298 LFASFVSVLPWGSC------NNPWNTPECKDKTKLLLDSCVISDHPKIQIKNSTFCMTAY 351 Query: 201 -----------------SATTYYWYREALNISSSISESGGLNWKMTICLLAAWVMVCLAM 243 S + Y+ L IS+ I G + W + +CL AWV+V ++ Sbjct: 352 PNVTMVNFTSQANKTFVSGSEEYFKYFVLKISAGIEYPGEIRWPLALCLFLAWVIVYASL 411 Query: 244 IKGIQSSGKV---SMLEPFLILLITI 266 KGI++SGKV + P+++L+I + Sbjct: 412 AKGIKTSGKVVYFTATFPYVVLVILL 437 >gi|4557046 solute carrier family 6 member 2 [Homo sapiens] Length = 617 Score = 166 bits (421), Expect = 2e-41 Identities = 85/230 (36%), Positives = 129/230 (56%), Gaps = 31/230 (13%) Query: 61 RPAWNSKLQYILAQVGFSVGLGNVWRFPYLCQKNGGGAYLLPYLILLMVIGIPLFFLELS 120 R W K+ ++L+ VGF+V L NVWRFPYLC KNGGGA+L+PY + L++ G+PLF++EL+ Sbjct: 56 RETWGKKIDFLLSVVGFAVDLANVWRFPYLCYKNGGGAFLIPYTLFLIIAGMPLFYMELA 115 Query: 121 VGQRIRRGSIGVWNYISPKLGGIGFASCVVCYFVALYYNVIIGWSLFYFSQSFQQPLPWD 180 +GQ R G+ VW I P G+G+A ++ +V YYNVII WSL+Y SF LPW Sbjct: 116 LGQYNREGAATVWK-ICPFFKGVGYAVILIALYVGFYYNVIIAWSLYYLFSSFTLNLPWT 174 Query: 181 QCPLVKNASHTFVEPECEQ---------SSATTYYWYREA------------LNISSSIS 219 C HT+ P C + T Y Y+ L+ SS I Sbjct: 175 DC------GHTWNSPNCTDPKLLNGSVLGNHTKYSKYKFTPAAEFYERGVLHLHESSGIH 228 Query: 220 ESGGLNWKMTICLLAAWVMVCLAMIKGIQSSGKVSMLE---PFLILLITI 266 + G W++ +CL+ +++ ++ KG+++SGKV + P+ +L + + Sbjct: 229 DIGLPQWQLLLCLMVVVIVLYFSLWKGVKTSGKVVWITATLPYFVLFVLL 278 >gi|4507041 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 [Homo sapiens] Length = 620 Score = 164 bits (415), Expect = 8e-41 Identities = 83/240 (34%), Positives = 136/240 (56%), Gaps = 30/240 (12%) Query: 60 ERPAWNSKLQYILAQVGFSVGLGNVWRFPYLCQKNGGGAYLLPYLILLMVIGIPLFFLEL 119 +R W K+ ++L+ +GF+V L NVWRFPYLC KNGGGA+L+PYL+ +++ G+PLF++EL Sbjct: 59 DRETWGKKIDFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLVPYLLFMVIAGMPLFYMEL 118 Query: 120 SVGQRIRRGSIGVWNYISPKLGGIGFASCVVCYFVALYYNVIIGWSLFYFSQSFQQPLPW 179 ++GQ R G+ GVW I P L G+GF ++ +V +YNVII W+L Y SF LPW Sbjct: 119 ALGQFNREGAAGVWK-ICPILKGVGFTVILISLYVGFFYNVIIAWALHYLFSSFTTELPW 177 Query: 180 DQCPLVKNASHTFVEPECEQ------------------SSATTYYWYREALNI--SSSIS 219 C ++++ P C ++ Y+ R L++ S I Sbjct: 178 IHC------NNSWNSPNCSDAHPGDSSGDSSGLNDTFGTTPAAEYFERGVLHLHQSHGID 231 Query: 220 ESGGLNWKMTICLLAAWVMVCLAMIKGIQSSGKVSMLE---PFLILLITISGFIPLSNSV 276 + G W++T CL+ V++ ++ KG+++SGKV + P+++L + + L ++ Sbjct: 232 DLGPPRWQLTACLVLVIVLLYFSLWKGVKTSGKVVWITATMPYVVLTALLLRGVTLPGAI 291 >gi|197276625 solute carrier family 6 (neurotransmitter transporter, taurine), member 6 isoform b [Homo sapiens] Length = 200 Score = 148 bits (373), Expect = 6e-36 Identities = 70/155 (45%), Positives = 95/155 (61%), Gaps = 13/155 (8%) Query: 54 GSEVEDE-------RPAWNSKLQYILAQVGFSVGLGNVWRFPYLCQKNGGGAYLLPYLIL 106 G+ EDE R W+SK+ ++L+ G VGLGNVWRFPYLC KNGGGA+L+PY I Sbjct: 27 GTRPEDEAEGKPPQREKWSSKIDFVLSVAGGFVGLGNVWRFPYLCYKNGGGAFLIPYFIF 86 Query: 107 LMVIGIPLFFLELSVGQRIRRGSIGVWNYISPKLGGIGFASCVVCYFVALYYNVIIGWSL 166 L G+P+FFLE+ +GQ G I W I P GIG+AS V+ + +YY VI+ W+ Sbjct: 87 LFGSGLPVFFLEIIIGQYTSEGGITCWEKICPLFSGIGYASVVIVSLLNVYYIVILAWAT 146 Query: 167 FYFSQSFQQPLPWDQCPLVKNASHTFVEPECEQSS 201 +Y QSFQ+ LPW C +H++ P C + + Sbjct: 147 YYLFQSFQKELPWAHC------NHSWNTPHCMEDT 175 >gi|218563758 solute carrier family 6 member 8 isoform 3 [Homo sapiens] Length = 520 Score = 100 bits (249), Expect = 1e-21 Identities = 50/168 (29%), Positives = 86/168 (51%), Gaps = 33/168 (19%) Query: 125 IRRGSIGVWNYISPKLGGIGFASCVVCYFVALYYNVIIGWSLFYFSQSFQQPLPWDQCPL 184 ++ GSI VWN I P G+G+AS V+ ++ YY +++ W +Y +SF LPW C Sbjct: 1 MKAGSINVWN-ICPLFKGLGYASMVIVFYCNTYYIMVLAWGFYYLVKSFTTTLPWATC-- 57 Query: 185 VKNASHTFVEPEC-----------------------EQSSATTYYWYREALNISSSISES 221 HT+ P+C ++ S +W + L +S + Sbjct: 58 ----GHTWNTPDCVEIFRHEDCANASLANLTCDQLADRRSPVIEFWENKVLRLSGGLEVP 113 Query: 222 GGLNWKMTICLLAAWVMVCLAMIKGIQSSGKV---SMLEPFLILLITI 266 G LNW++T+CLLA WV+V + KG++S+GK+ + P+++L++ + Sbjct: 114 GALNWEVTLCLLACWVLVYFCVWKGVKSTGKIVYFTATFPYVVLVVLL 161 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.321 0.138 0.428 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 10,818,586 Number of Sequences: 37866 Number of extensions: 468132 Number of successful extensions: 1818 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 42 Number of HSP's successfully gapped in prelim test: 11 Number of HSP's that attempted gapping in prelim test: 1706 Number of HSP's gapped (non-prelim): 84 length of query: 289 length of database: 18,247,518 effective HSP length: 101 effective length of query: 188 effective length of database: 14,423,052 effective search space: 2711533776 effective search space used: 2711533776 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.