Guide to the Human Genome
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Search of human proteins with 21361693

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|21361693 solute carrier family 6, member 15 isoform 2 [Homo
sapiens]
         (289 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|21361693 solute carrier family 6, member 15 isoform 2 [Homo s...   591   e-169
gi|33354281 solute carrier family 6, member 15 isoform 1 [Homo s...   524   e-149
gi|58219014 solute carrier family 6, member 17 [Homo sapiens]         378   e-105
gi|226437581 solute carrier family 6, member 15 isoform 3 [Homo ...   310   7e-85
gi|11181770 solute carrier family 6, member 20 isoform 1 [Homo s...   249   3e-66
gi|12408638 solute carrier family 6, member 20 isoform 2 [Homo s...   248   3e-66
gi|51468073 solute carrier family 6, member 19 [Homo sapiens]         243   2e-64
gi|194018524 solute carrier family 6, member 18 [Homo sapiens]        242   2e-64
gi|55749589 solute carrier family 6, member 16 [Homo sapiens]         202   3e-52
gi|171184408 solute carrier family 6 (neurotransmitter transport...   191   8e-49
gi|171184406 solute carrier family 6 (neurotransmitter transport...   191   8e-49
gi|171184404 solute carrier family 6 (neurotransmitter transport...   191   8e-49
gi|5032097 solute carrier family 6 member 8 isoform 1 [Homo sapi...   189   2e-48
gi|218563756 solute carrier family 6 member 8 isoform 2 [Homo sa...   189   2e-48
gi|197276623 solute carrier family 6 (neurotransmitter transport...   183   1e-46
gi|54607094 solute carrier family 6 (neurotransmitter transporte...   183   1e-46
gi|6005715 solute carrier family 6 (amino acid transporter), mem...   182   2e-46
gi|4507043 solute carrier family 6 member 4 [Homo sapiens]            180   1e-45
gi|21361581 solute carrier family 6 (neurotransmitter transporte...   180   1e-45
gi|7657587 solute carrier family 6 (neurotransmitter transporter...   176   2e-44
gi|188528618 solute carrier family 6 (neurotransmitter transport...   175   4e-44
gi|134304856 solute carrier family 6, member 7 [Homo sapiens]         174   6e-44
gi|67782317 solute carrier family 6 member 9 isoform 3 [Homo sap...   169   3e-42
gi|67782315 solute carrier family 6 member 9 isoform 2 [Homo sap...   169   3e-42
gi|67782313 solute carrier family 6 member 9 isoform 1 [Homo sap...   169   3e-42
gi|92859670 solute carrier family 6 (neurotransmitter transporte...   169   3e-42
gi|4557046 solute carrier family 6 member 2 [Homo sapiens]            166   2e-41
gi|4507041 solute carrier family 6 (neurotransmitter transporter...   164   8e-41
gi|197276625 solute carrier family 6 (neurotransmitter transport...   148   6e-36
gi|218563758 solute carrier family 6 member 8 isoform 3 [Homo sa...   100   1e-21

>gi|21361693 solute carrier family 6, member 15 isoform 2 [Homo
           sapiens]
          Length = 289

 Score =  591 bits (1523), Expect = e-169
 Identities = 289/289 (100%), Positives = 289/289 (100%)

Query: 1   MPKNSKVVKRELDDDVTESVKDLLSNEDAADDAFKTSELIVDGQEEKDTDVEEGSEVEDE 60
           MPKNSKVVKRELDDDVTESVKDLLSNEDAADDAFKTSELIVDGQEEKDTDVEEGSEVEDE
Sbjct: 1   MPKNSKVVKRELDDDVTESVKDLLSNEDAADDAFKTSELIVDGQEEKDTDVEEGSEVEDE 60

Query: 61  RPAWNSKLQYILAQVGFSVGLGNVWRFPYLCQKNGGGAYLLPYLILLMVIGIPLFFLELS 120
           RPAWNSKLQYILAQVGFSVGLGNVWRFPYLCQKNGGGAYLLPYLILLMVIGIPLFFLELS
Sbjct: 61  RPAWNSKLQYILAQVGFSVGLGNVWRFPYLCQKNGGGAYLLPYLILLMVIGIPLFFLELS 120

Query: 121 VGQRIRRGSIGVWNYISPKLGGIGFASCVVCYFVALYYNVIIGWSLFYFSQSFQQPLPWD 180
           VGQRIRRGSIGVWNYISPKLGGIGFASCVVCYFVALYYNVIIGWSLFYFSQSFQQPLPWD
Sbjct: 121 VGQRIRRGSIGVWNYISPKLGGIGFASCVVCYFVALYYNVIIGWSLFYFSQSFQQPLPWD 180

Query: 181 QCPLVKNASHTFVEPECEQSSATTYYWYREALNISSSISESGGLNWKMTICLLAAWVMVC 240
           QCPLVKNASHTFVEPECEQSSATTYYWYREALNISSSISESGGLNWKMTICLLAAWVMVC
Sbjct: 181 QCPLVKNASHTFVEPECEQSSATTYYWYREALNISSSISESGGLNWKMTICLLAAWVMVC 240

Query: 241 LAMIKGIQSSGKVSMLEPFLILLITISGFIPLSNSVTDFCGQITHNTSF 289
           LAMIKGIQSSGKVSMLEPFLILLITISGFIPLSNSVTDFCGQITHNTSF
Sbjct: 241 LAMIKGIQSSGKVSMLEPFLILLITISGFIPLSNSVTDFCGQITHNTSF 289


>gi|33354281 solute carrier family 6, member 15 isoform 1 [Homo
           sapiens]
          Length = 730

 Score =  524 bits (1350), Expect = e-149
 Identities = 258/279 (92%), Positives = 266/279 (95%), Gaps = 3/279 (1%)

Query: 1   MPKNSKVVKRELDDDVTESVKDLLSNEDAADDAFKTSELIVDGQEEKDTDVEEGSEVEDE 60
           MPKNSKVVKRELDDDVTESVKDLLSNEDAADDAFKTSELIVDGQEEKDTDVEEGSEVEDE
Sbjct: 1   MPKNSKVVKRELDDDVTESVKDLLSNEDAADDAFKTSELIVDGQEEKDTDVEEGSEVEDE 60

Query: 61  RPAWNSKLQYILAQVGFSVGLGNVWRFPYLCQKNGGGAYLLPYLILLMVIGIPLFFLELS 120
           RPAWNSKLQYILAQVGFSVGLGNVWRFPYLCQKNGGGAYLLPYLILLMVIGIPLFFLELS
Sbjct: 61  RPAWNSKLQYILAQVGFSVGLGNVWRFPYLCQKNGGGAYLLPYLILLMVIGIPLFFLELS 120

Query: 121 VGQRIRRGSIGVWNYISPKLGGIGFASCVVCYFVALYYNVIIGWSLFYFSQSFQQPLPWD 180
           VGQRIRRGSIGVWNYISPKLGGIGFASCVVCYFVALYYNVIIGWSLFYFSQSFQQPLPWD
Sbjct: 121 VGQRIRRGSIGVWNYISPKLGGIGFASCVVCYFVALYYNVIIGWSLFYFSQSFQQPLPWD 180

Query: 181 QCPLVKNASHTFVEPECEQSSATTYYWYREALNISSSISESGGLNWKMTICLLAAWVMVC 240
           QCPLVKNASHTFVEPECEQSSATTYYWYREALNISSSISESGGLNWKMTICLLAAWVMVC
Sbjct: 181 QCPLVKNASHTFVEPECEQSSATTYYWYREALNISSSISESGGLNWKMTICLLAAWVMVC 240

Query: 241 LAMIKGIQSSGKV---SMLEPFLILLITISGFIPLSNSV 276
           LAMIKGIQSSGK+   S L P+++L+  +     L+ S+
Sbjct: 241 LAMIKGIQSSGKIIYFSSLFPYVVLICFLIRAFLLNGSI 279


>gi|58219014 solute carrier family 6, member 17 [Homo sapiens]
          Length = 727

 Score =  378 bits (970), Expect = e-105
 Identities = 188/267 (70%), Positives = 222/267 (83%), Gaps = 8/267 (2%)

Query: 1   MPKNSKVVKRELDDD-VTESVKDLLSNEDAADDAFKTSELIVDGQEE-KDTDVEEGSEVE 58
           MPKNSKV +RE   + VTESV DLL+ E+  D  +K S L V G+   K   VEE  + E
Sbjct: 1   MPKNSKVTQREHSSEHVTESVADLLALEEPVD--YKQSVLNVAGEAGGKQKAVEEELDAE 58

Query: 59  DERPAWNSKLQYILAQVGFSVGLGNVWRFPYLCQKNGGGAYLLPYLILLMVIGIPLFFLE 118
           D RPAWNSKLQYILAQ+GFSVGLGN+WRFPYLCQKNGGGAYL+PYL+LL++IGIPLFFLE
Sbjct: 59  D-RPAWNSKLQYILAQIGFSVGLGNIWRFPYLCQKNGGGAYLVPYLVLLIIIGIPLFFLE 117

Query: 119 LSVGQRIRRGSIGVWNYISPKLGGIGFASCVVCYFVALYYNVIIGWSLFYFSQSFQQPLP 178
           L+VGQRIRRGSIGVW+YI P+LGGIGF+SC+VC FV LYYNVIIGWS+FYF +SFQ PLP
Sbjct: 118 LAVGQRIRRGSIGVWHYICPRLGGIGFSSCIVCLFVGLYYNVIIGWSIFYFFKSFQYPLP 177

Query: 179 WDQCPLVKNASHTFVEPECEQSSATTYYWYREALNISSSISESGGLNWKMTICLLAAWVM 238
           W +CP+V+N S   VE ECE+SSATTY+WYREAL+IS SISESGGLNWKMT+CLL AW +
Sbjct: 178 WSECPVVRNGSVAVVEAECEKSSATTYFWYREALDISDSISESGGLNWKMTLCLLVAWSI 237

Query: 239 VCLAMIKGIQSSGKV---SMLEPFLIL 262
           V +A++KGIQSSGKV   S L P+++L
Sbjct: 238 VGMAVVKGIQSSGKVMYFSSLFPYVVL 264


>gi|226437581 solute carrier family 6, member 15 isoform 3 [Homo
           sapiens]
          Length = 623

 Score =  310 bits (795), Expect = 7e-85
 Identities = 151/172 (87%), Positives = 159/172 (92%), Gaps = 3/172 (1%)

Query: 108 MVIGIPLFFLELSVGQRIRRGSIGVWNYISPKLGGIGFASCVVCYFVALYYNVIIGWSLF 167
           MVIGIPLFFLELSVGQRIRRGSIGVWNYISPKLGGIGFASCVVCYFVALYYNVIIGWSLF
Sbjct: 1   MVIGIPLFFLELSVGQRIRRGSIGVWNYISPKLGGIGFASCVVCYFVALYYNVIIGWSLF 60

Query: 168 YFSQSFQQPLPWDQCPLVKNASHTFVEPECEQSSATTYYWYREALNISSSISESGGLNWK 227
           YFSQSFQQPLPWDQCPLVKNASHTFVEPECEQSSATTYYWYREALNISSSISESGGLNWK
Sbjct: 61  YFSQSFQQPLPWDQCPLVKNASHTFVEPECEQSSATTYYWYREALNISSSISESGGLNWK 120

Query: 228 MTICLLAAWVMVCLAMIKGIQSSGKV---SMLEPFLILLITISGFIPLSNSV 276
           MTICLLAAWVMVCLAMIKGIQSSGK+   S L P+++L+  +     L+ S+
Sbjct: 121 MTICLLAAWVMVCLAMIKGIQSSGKIIYFSSLFPYVVLICFLIRAFLLNGSI 172


>gi|11181770 solute carrier family 6, member 20 isoform 1 [Homo
           sapiens]
          Length = 592

 Score =  249 bits (635), Expect = 3e-66
 Identities = 110/211 (52%), Positives = 157/211 (74%), Gaps = 5/211 (2%)

Query: 57  VEDERPAWNSKLQYILAQVGFSVGLGNVWRFPYLCQKNGGGAYLLPYLILLMVIGIPLFF 116
           +E  RP W + LQ++ A + ++VGLGNVWRFPYLCQ  GGG++L+PY+I+L+V G+PL +
Sbjct: 1   MEKARPLWANSLQFVFACISYAVGLGNVWRFPYLCQMYGGGSFLVPYIIMLIVEGMPLLY 60

Query: 117 LELSVGQRIRRGSIGVWNYISPKLGGIGFASCVVCYFVALYYNVIIGWSLFYFSQSFQQP 176
           LEL+VGQR+R+GSIG W  ISP L G+G AS VV +F+++YYNVI  W+ +Y   SFQ P
Sbjct: 61  LELAVGQRMRQGSIGAWRTISPYLSGVGVASVVVSFFLSMYYNVINAWAFWYLFHSFQDP 120

Query: 177 LPWDQCPLVKNASHTFVEPECEQSSATTYYWYREALNISSSISESGGLNWKMTICLLAAW 236
           LPW  CPL  N +HT  + ECE++S+T Y+WYR+ LNIS S+ E+GG+ W+  +CLL AW
Sbjct: 121 LPWSVCPL--NGNHTGYDEECEKASSTQYFWYRKTLNISPSLQENGGVQWEPALCLLLAW 178

Query: 237 VMVCLAMIKGIQSSGKVSMLE---PFLILLI 264
           ++V L +++G +S+GKV       P+ +L+I
Sbjct: 179 LVVYLCILRGTESTGKVVYFTASLPYCVLII 209


>gi|12408638 solute carrier family 6, member 20 isoform 2 [Homo
           sapiens]
          Length = 555

 Score =  248 bits (634), Expect = 3e-66
 Identities = 107/200 (53%), Positives = 152/200 (76%), Gaps = 2/200 (1%)

Query: 57  VEDERPAWNSKLQYILAQVGFSVGLGNVWRFPYLCQKNGGGAYLLPYLILLMVIGIPLFF 116
           +E  RP W + LQ++ A + ++VGLGNVWRFPYLCQ  GGG++L+PY+I+L+V G+PL +
Sbjct: 1   MEKARPLWANSLQFVFACISYAVGLGNVWRFPYLCQMYGGGSFLVPYIIMLIVEGMPLLY 60

Query: 117 LELSVGQRIRRGSIGVWNYISPKLGGIGFASCVVCYFVALYYNVIIGWSLFYFSQSFQQP 176
           LEL+VGQR+R+GSIG W  ISP L G+G AS VV +F+++YYNVI  W+ +Y   SFQ P
Sbjct: 61  LELAVGQRMRQGSIGAWRTISPYLSGVGVASVVVSFFLSMYYNVINAWAFWYLFHSFQDP 120

Query: 177 LPWDQCPLVKNASHTFVEPECEQSSATTYYWYREALNISSSISESGGLNWKMTICLLAAW 236
           LPW  CPL  N +HT  + ECE++S+T Y+WYR+ LNIS S+ E+GG+ W+  +CLL AW
Sbjct: 121 LPWSVCPL--NGNHTGYDEECEKASSTQYFWYRKTLNISPSLQENGGVQWEPALCLLLAW 178

Query: 237 VMVCLAMIKGIQSSGKVSML 256
           ++V L +++G +S+GK+  L
Sbjct: 179 LVVYLCILRGTESTGKIEQL 198


>gi|51468073 solute carrier family 6, member 19 [Homo sapiens]
          Length = 634

 Score =  243 bits (619), Expect = 2e-64
 Identities = 112/236 (47%), Positives = 158/236 (66%), Gaps = 5/236 (2%)

Query: 56  EVEDERPAWNSKLQYILAQVGFSVGLGNVWRFPYLCQKNGGGAYLLPYLILLMVIGIPLF 115
           E    RP W++K QY+L  +GF VGLGNVWRFPYLCQ +GGGA+++P+LILL++ GIPL 
Sbjct: 27  EEASSRPKWDNKAQYMLTCLGFCVGLGNVWRFPYLCQSHGGGAFMIPFLILLVLEGIPLL 86

Query: 116 FLELSVGQRIRRGSIGVWNYISPKLGGIGFASCVVCYFVALYYNVIIGWSLFYFSQSFQQ 175
           +LE ++GQR+RRGS+GVW+ I P L G+G AS +  + V LYYN II W ++Y   SFQ+
Sbjct: 87  YLEFAIGQRLRRGSLGVWSSIHPALKGLGLASMLTSFMVGLYYNTIISWIMWYLFNSFQE 146

Query: 176 PLPWDQCPLVKNASHTFVEPECEQSSATTYYWYREALNISSSISESGGLNWKMTICLLAA 235
           PLPW  CPL  N + T    EC +SS   Y+WYRE LNIS+SIS+SG + W M +CL  A
Sbjct: 147 PLPWSDCPL--NENQTGYVDECARSSPVDYFWYRETLNISTSISDSGSIQWWMLLCLACA 204

Query: 236 WVMVCLAMIKGIQSSGK---VSMLEPFLILLITISGFIPLSNSVTDFCGQITHNTS 288
           W ++ +  I+GI+++GK   ++   P+++L I +   + L  +        T N +
Sbjct: 205 WSVLYMCTIRGIETTGKAVYITSTLPYVVLTIFLIRGLTLKGATNGIVFLFTPNVT 260


>gi|194018524 solute carrier family 6, member 18 [Homo sapiens]
          Length = 628

 Score =  242 bits (618), Expect = 2e-64
 Identities = 108/212 (50%), Positives = 156/212 (73%), Gaps = 5/212 (2%)

Query: 56  EVEDERPAWNSKLQYILAQVGFSVGLGNVWRFPYLCQKNGGGAYLLPYLILLMVIGIPLF 115
           ++ DERP W++K QY+L+  GF+VGLGN+WRFPYLCQ  GGGA+L+PY+I L+  GIP+F
Sbjct: 13  DLGDERPKWDNKAQYLLSCTGFAVGLGNIWRFPYLCQTYGGGAFLIPYVIALVFEGIPIF 72

Query: 116 FLELSVGQRIRRGSIGVWNYISPKLGGIGFASCVVCYFVALYYNVIIGWSLFYFSQSFQQ 175
            +EL++GQR+R+GS+GVW  ISP L G+G     + + ++LYYN I+ W L+Y   SFQ 
Sbjct: 73  HVELAIGQRLRKGSVGVWTAISPYLSGVGLGCVTLSFLISLYYNTIVAWVLWYLLNSFQH 132

Query: 176 PLPWDQCPLVKNASHTFVEPECEQSSATTYYWYREALNISSSISESGGLNWKMTICLLAA 235
           PLPW  CP   N +  FVE EC+ SSA +Y+WYR+ LNI++ I++SG + W + ICL A+
Sbjct: 133 PLPWSSCPPDLNRT-GFVE-ECQGSSAVSYFWYRQTLNITADINDSGSIQWWLLICLAAS 190

Query: 236 WVMVCLAMIKGIQSSGKV---SMLEPFLILLI 264
           W +V + +I+GI+++GKV   + L P+L+L I
Sbjct: 191 WAVVYMCVIRGIETTGKVIYFTALFPYLVLTI 222


>gi|55749589 solute carrier family 6, member 16 [Homo sapiens]
          Length = 736

 Score =  202 bits (514), Expect = 3e-52
 Identities = 92/216 (42%), Positives = 142/216 (65%), Gaps = 2/216 (0%)

Query: 55  SEVEDERPAWNSKLQYILAQVGFSVGLGNVWRFPYLCQKNGGGAYLLPYLILLMVIGIPL 114
           SEV   RP W+SK +YILAQVGFS+    +WRF YL   +GG ++   Y+ +L ++G+PL
Sbjct: 97  SEVLLARPFWSSKTEYILAQVGFSMKPSCLWRFAYLWLNSGGCSFAAIYIFMLFLVGVPL 156

Query: 115 FFLELSVGQRIRRGSIGVWNYISPKLGGIGFASCVVCYFVALYYNVIIGWSLFYFSQSFQ 174
            FLE++ GQ +R+G +GVW  I+P +GG+G++S +VC+ + LY+NV+  W +FY SQSFQ
Sbjct: 157 LFLEMAAGQSMRQGGMGVWKIIAPWIGGVGYSSFMVCFILGLYFNVVNSWIIFYMSQSFQ 216

Query: 175 QPLPWDQCPLVKNASHTFVEPECEQSSATTYYWYREALNISSSISESGGLNWKMTICLLA 234
            P+PW++CPL  N+S    +PECE+++ + Y+WY++AL  S  I + G   + + +    
Sbjct: 217 FPVPWEKCPLTMNSSG--FDPECERTTPSIYFWYQQALKASDRIEDGGSPVYSLVLPFFL 274

Query: 235 AWVMVCLAMIKGIQSSGKVSMLEPFLILLITISGFI 270
            W +V   MI G++S+GKV  +   L   I +  FI
Sbjct: 275 CWCLVGAFMINGLKSTGKVIYVLVLLPCFIIVGFFI 310


>gi|171184408 solute carrier family 6 (neurotransmitter transporter,
           betaine/GABA), member 12 [Homo sapiens]
          Length = 614

 Score =  191 bits (484), Expect = 8e-49
 Identities = 95/236 (40%), Positives = 139/236 (58%), Gaps = 14/236 (5%)

Query: 44  QEEKDTDVEEGSEVEDERPAWNSKLQYILAQVGFSVGLGNVWRFPYLCQKNGGGAYLLPY 103
           +E +  D E+  +V+D R  W +K++++L+  G  +GLGNVWRFPYLC KNGGGA+ +PY
Sbjct: 20  EEGEKLDQEDEDQVKD-RGQWTNKMEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFIPY 78

Query: 104 LILLMVIGIPLFFLELSVGQRIRRGSIGVWNYISPKLGGIGFASCVVCYFVALYYNVIIG 163
            I   V GIP+FFLE+++GQ   +GS+  W  I P   GIG AS V+  ++ +YY +I+ 
Sbjct: 79  FIFFFVCGIPVFFLEVALGQYTSQGSVTAWRKICPLFQGIGLASVVIESYLNVYYIIILA 138

Query: 164 WSLFYFSQSFQQPLPWDQCPLVKNASHT----------FVEPECEQSSATTYYWYREALN 213
           W+LFY   SF   LPW  C    N  H            V P    +S    +W R  L 
Sbjct: 139 WALFYLFSSFTSELPWTTCNNFWNTEHCTDFLNHSGAGTVTPFENFTSPVMEFWERRVLG 198

Query: 214 ISSSISESGGLNWKMTICLLAAWVMVCLAMIKGIQSSGKV---SMLEPFLILLITI 266
           I+S I + G L W++ +CLL AWV+    + KG++S+GKV   +   P+L+L+I +
Sbjct: 199 ITSGIHDLGSLRWELALCLLLAWVICYFCIWKGVKSTGKVVYFTATFPYLMLVILL 254


>gi|171184406 solute carrier family 6 (neurotransmitter transporter,
           betaine/GABA), member 12 [Homo sapiens]
          Length = 614

 Score =  191 bits (484), Expect = 8e-49
 Identities = 95/236 (40%), Positives = 139/236 (58%), Gaps = 14/236 (5%)

Query: 44  QEEKDTDVEEGSEVEDERPAWNSKLQYILAQVGFSVGLGNVWRFPYLCQKNGGGAYLLPY 103
           +E +  D E+  +V+D R  W +K++++L+  G  +GLGNVWRFPYLC KNGGGA+ +PY
Sbjct: 20  EEGEKLDQEDEDQVKD-RGQWTNKMEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFIPY 78

Query: 104 LILLMVIGIPLFFLELSVGQRIRRGSIGVWNYISPKLGGIGFASCVVCYFVALYYNVIIG 163
            I   V GIP+FFLE+++GQ   +GS+  W  I P   GIG AS V+  ++ +YY +I+ 
Sbjct: 79  FIFFFVCGIPVFFLEVALGQYTSQGSVTAWRKICPLFQGIGLASVVIESYLNVYYIIILA 138

Query: 164 WSLFYFSQSFQQPLPWDQCPLVKNASHT----------FVEPECEQSSATTYYWYREALN 213
           W+LFY   SF   LPW  C    N  H            V P    +S    +W R  L 
Sbjct: 139 WALFYLFSSFTSELPWTTCNNFWNTEHCTDFLNHSGAGTVTPFENFTSPVMEFWERRVLG 198

Query: 214 ISSSISESGGLNWKMTICLLAAWVMVCLAMIKGIQSSGKV---SMLEPFLILLITI 266
           I+S I + G L W++ +CLL AWV+    + KG++S+GKV   +   P+L+L+I +
Sbjct: 199 ITSGIHDLGSLRWELALCLLLAWVICYFCIWKGVKSTGKVVYFTATFPYLMLVILL 254


>gi|171184404 solute carrier family 6 (neurotransmitter transporter,
           betaine/GABA), member 12 [Homo sapiens]
          Length = 614

 Score =  191 bits (484), Expect = 8e-49
 Identities = 95/236 (40%), Positives = 139/236 (58%), Gaps = 14/236 (5%)

Query: 44  QEEKDTDVEEGSEVEDERPAWNSKLQYILAQVGFSVGLGNVWRFPYLCQKNGGGAYLLPY 103
           +E +  D E+  +V+D R  W +K++++L+  G  +GLGNVWRFPYLC KNGGGA+ +PY
Sbjct: 20  EEGEKLDQEDEDQVKD-RGQWTNKMEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFIPY 78

Query: 104 LILLMVIGIPLFFLELSVGQRIRRGSIGVWNYISPKLGGIGFASCVVCYFVALYYNVIIG 163
            I   V GIP+FFLE+++GQ   +GS+  W  I P   GIG AS V+  ++ +YY +I+ 
Sbjct: 79  FIFFFVCGIPVFFLEVALGQYTSQGSVTAWRKICPLFQGIGLASVVIESYLNVYYIIILA 138

Query: 164 WSLFYFSQSFQQPLPWDQCPLVKNASHT----------FVEPECEQSSATTYYWYREALN 213
           W+LFY   SF   LPW  C    N  H            V P    +S    +W R  L 
Sbjct: 139 WALFYLFSSFTSELPWTTCNNFWNTEHCTDFLNHSGAGTVTPFENFTSPVMEFWERRVLG 198

Query: 214 ISSSISESGGLNWKMTICLLAAWVMVCLAMIKGIQSSGKV---SMLEPFLILLITI 266
           I+S I + G L W++ +CLL AWV+    + KG++S+GKV   +   P+L+L+I +
Sbjct: 199 ITSGIHDLGSLRWELALCLLLAWVICYFCIWKGVKSTGKVVYFTATFPYLMLVILL 254


>gi|5032097 solute carrier family 6 member 8 isoform 1 [Homo
           sapiens]
          Length = 635

 Score =  189 bits (481), Expect = 2e-48
 Identities = 88/232 (37%), Positives = 139/232 (59%), Gaps = 33/232 (14%)

Query: 61  RPAWNSKLQYILAQVGFSVGLGNVWRFPYLCQKNGGGAYLLPYLILLMVIGIPLFFLELS 120
           R  W  ++ +I++ VGF+VGLGNVWRFPYLC KNGGG +L+PY+++ +V GIP+FFLE+S
Sbjct: 52  RETWTRQMDFIMSCVGFAVGLGNVWRFPYLCYKNGGGVFLIPYVLIALVGGIPIFFLEIS 111

Query: 121 VGQRIRRGSIGVWNYISPKLGGIGFASCVVCYFVALYYNVIIGWSLFYFSQSFQQPLPWD 180
           +GQ ++ GSI VWN I P   G+G+AS V+ ++   YY +++ W  +Y  +SF   LPW 
Sbjct: 112 LGQFMKAGSINVWN-ICPLFKGLGYASMVIVFYCNTYYIMVLAWGFYYLVKSFTTTLPWA 170

Query: 181 QCPLVKNASHTFVEPEC-----------------------EQSSATTYYWYREALNISSS 217
            C       HT+  P+C                       ++ S    +W  + L +S  
Sbjct: 171 TC------GHTWNTPDCVEIFRHEDCANASLANLTCDQLADRRSPVIEFWENKVLRLSGG 224

Query: 218 ISESGGLNWKMTICLLAAWVMVCLAMIKGIQSSGKV---SMLEPFLILLITI 266
           +   G LNW++T+CLLA WV+V   + KG++S+GK+   +   P+++L++ +
Sbjct: 225 LEVPGALNWEVTLCLLACWVLVYFCVWKGVKSTGKIVYFTATFPYVVLVVLL 276


>gi|218563756 solute carrier family 6 member 8 isoform 2 [Homo
           sapiens]
          Length = 625

 Score =  189 bits (481), Expect = 2e-48
 Identities = 88/232 (37%), Positives = 139/232 (59%), Gaps = 33/232 (14%)

Query: 61  RPAWNSKLQYILAQVGFSVGLGNVWRFPYLCQKNGGGAYLLPYLILLMVIGIPLFFLELS 120
           R  W  ++ +I++ VGF+VGLGNVWRFPYLC KNGGG +L+PY+++ +V GIP+FFLE+S
Sbjct: 52  RETWTRQMDFIMSCVGFAVGLGNVWRFPYLCYKNGGGVFLIPYVLIALVGGIPIFFLEIS 111

Query: 121 VGQRIRRGSIGVWNYISPKLGGIGFASCVVCYFVALYYNVIIGWSLFYFSQSFQQPLPWD 180
           +GQ ++ GSI VWN I P   G+G+AS V+ ++   YY +++ W  +Y  +SF   LPW 
Sbjct: 112 LGQFMKAGSINVWN-ICPLFKGLGYASMVIVFYCNTYYIMVLAWGFYYLVKSFTTTLPWA 170

Query: 181 QCPLVKNASHTFVEPEC-----------------------EQSSATTYYWYREALNISSS 217
            C       HT+  P+C                       ++ S    +W  + L +S  
Sbjct: 171 TC------GHTWNTPDCVEIFRHEDCANASLANLTCDQLADRRSPVIEFWENKVLRLSGG 224

Query: 218 ISESGGLNWKMTICLLAAWVMVCLAMIKGIQSSGKV---SMLEPFLILLITI 266
           +   G LNW++T+CLLA WV+V   + KG++S+GK+   +   P+++L++ +
Sbjct: 225 LEVPGALNWEVTLCLLACWVLVYFCVWKGVKSTGKIVYFTATFPYVVLVVLL 276


>gi|197276623 solute carrier family 6 (neurotransmitter transporter,
           taurine), member 6 isoform a [Homo sapiens]
          Length = 620

 Score =  183 bits (465), Expect = 1e-46
 Identities = 94/241 (39%), Positives = 135/241 (56%), Gaps = 34/241 (14%)

Query: 54  GSEVEDE-------RPAWNSKLQYILAQVGFSVGLGNVWRFPYLCQKNGGGAYLLPYLIL 106
           G+  EDE       R  W+SK+ ++L+  G  VGLGNVWRFPYLC KNGGGA+L+PY I 
Sbjct: 27  GTRPEDEAEGKPPQREKWSSKIDFVLSVAGGFVGLGNVWRFPYLCYKNGGGAFLIPYFIF 86

Query: 107 LMVIGIPLFFLELSVGQRIRRGSIGVWNYISPKLGGIGFASCVVCYFVALYYNVIIGWSL 166
           L   G+P+FFLE+ +GQ    G I  W  I P   GIG+AS V+   + +YY VI+ W+ 
Sbjct: 87  LFGSGLPVFFLEIIIGQYTSEGGITCWEKICPLFSGIGYASVVIVSLLNVYYIVILAWAT 146

Query: 167 FYFSQSFQQPLPWDQCPLVKNASHTFVEPECEQS------------SATTY------YWY 208
           +Y  QSFQ+ LPW  C      +H++  P C +             S+T +      +W 
Sbjct: 147 YYLFQSFQKELPWAHC------NHSWNTPHCMEDTMRKNKSVWITISSTNFTSPVIEFWE 200

Query: 209 REALNISSSISESGGLNWKMTICLLAAWVMVCLAMIKGIQSSGKV---SMLEPFLILLIT 265
           R  L++S  I   G L W + +CLL  W++    + KG++S+GKV   +   PF +LL+ 
Sbjct: 201 RNVLSLSPGIDHPGSLKWDLALCLLLVWLVCFFCIWKGVRSTGKVVYFTATFPFAMLLVL 260

Query: 266 I 266
           +
Sbjct: 261 L 261


>gi|54607094 solute carrier family 6 (neurotransmitter transporter,
           taurine), member 6 isoform a [Homo sapiens]
          Length = 620

 Score =  183 bits (465), Expect = 1e-46
 Identities = 94/241 (39%), Positives = 135/241 (56%), Gaps = 34/241 (14%)

Query: 54  GSEVEDE-------RPAWNSKLQYILAQVGFSVGLGNVWRFPYLCQKNGGGAYLLPYLIL 106
           G+  EDE       R  W+SK+ ++L+  G  VGLGNVWRFPYLC KNGGGA+L+PY I 
Sbjct: 27  GTRPEDEAEGKPPQREKWSSKIDFVLSVAGGFVGLGNVWRFPYLCYKNGGGAFLIPYFIF 86

Query: 107 LMVIGIPLFFLELSVGQRIRRGSIGVWNYISPKLGGIGFASCVVCYFVALYYNVIIGWSL 166
           L   G+P+FFLE+ +GQ    G I  W  I P   GIG+AS V+   + +YY VI+ W+ 
Sbjct: 87  LFGSGLPVFFLEIIIGQYTSEGGITCWEKICPLFSGIGYASVVIVSLLNVYYIVILAWAT 146

Query: 167 FYFSQSFQQPLPWDQCPLVKNASHTFVEPECEQS------------SATTY------YWY 208
           +Y  QSFQ+ LPW  C      +H++  P C +             S+T +      +W 
Sbjct: 147 YYLFQSFQKELPWAHC------NHSWNTPHCMEDTMRKNKSVWITISSTNFTSPVIEFWE 200

Query: 209 REALNISSSISESGGLNWKMTICLLAAWVMVCLAMIKGIQSSGKV---SMLEPFLILLIT 265
           R  L++S  I   G L W + +CLL  W++    + KG++S+GKV   +   PF +LL+ 
Sbjct: 201 RNVLSLSPGIDHPGSLKWDLALCLLLVWLVCFFCIWKGVRSTGKVVYFTATFPFAMLLVL 260

Query: 266 I 266
           +
Sbjct: 261 L 261


>gi|6005715 solute carrier family 6 (amino acid transporter), member
           14 [Homo sapiens]
          Length = 642

 Score =  182 bits (463), Expect = 2e-46
 Identities = 104/273 (38%), Positives = 146/273 (53%), Gaps = 42/273 (15%)

Query: 34  FKTSELIVDGQEEKDTDVEEGSEVEDERPAWNSKLQYILAQVGFSVGLGNVWRFPYLCQK 93
           FK  E        ++  V E  E +D R  W+ K  Y+L+ +G++VGLGNVWRFPYL   
Sbjct: 10  FKCREKEKVSASSENFHVGENDENQD-RGNWSKKSDYLLSMIGYAVGLGNVWRFPYLTYS 68

Query: 94  NGGGAYLLPYLILLMVIGIPLFFLELSVGQRIRRGSIGVWNYISPKLGGIGFASCVVCYF 153
           NGGGA+L+PY I+L + G+PLFFLE S+GQ    G + VW  I P   G+G    ++  F
Sbjct: 69  NGGGAFLIPYAIMLALAGLPLFFLECSLGQFASLGPVSVWR-ILPLFQGVGITMVLISIF 127

Query: 154 VALYYNVIIGWSLFYFSQSFQQPLPWDQCP--LVKNASHTFVEPECEQSSA--------- 202
           V +YYNVII +SL+Y   SFQ  LPW  C     KN S + +   C  S+          
Sbjct: 128 VTIYYNVIIAYSLYYMFASFQSELPWKNCSSWSDKNCSRSPIVTHCNVSTVNKGIQEIIQ 187

Query: 203 --------------------------TTYYWYREALNISSSISESGGLNWKMTICLLAAW 236
                                     +  YW + AL  SS ++E+G + W + +CLL AW
Sbjct: 188 MNKSWVDINNFTCINGSEIYQPGQLPSEQYWNKVALQRSSGMNETGVIVWYLALCLLLAW 247

Query: 237 VMVCLAMIKGIQSSGKV---SMLEPFLILLITI 266
           ++V  A+ KGI+SSGKV   + L P+++LLI +
Sbjct: 248 LIVGAALFKGIKSSGKVVYFTALFPYVVLLILL 280


>gi|4507043 solute carrier family 6 member 4 [Homo sapiens]
          Length = 630

 Score =  180 bits (457), Expect = 1e-45
 Identities = 82/221 (37%), Positives = 136/221 (61%), Gaps = 12/221 (5%)

Query: 58  EDERPAWNSKLQYILAQVGFSVGLGNVWRFPYLCQKNGGGAYLLPYLILLMVIGIPLFFL 117
           + ER  W  K+ ++L+ +G++V LGNVWRFPY+C +NGGGA+LLPY I+ +  GIPLF++
Sbjct: 76  QGERETWGKKVDFLLSVIGYAVDLGNVWRFPYICYQNGGGAFLLPYTIMAIFGGIPLFYM 135

Query: 118 ELSVGQRIRRGSIGVWNYISPKLGGIGFASCVVCYFVALYYNVIIGWSLFYFSQSFQQPL 177
           EL++GQ  R G I +W  I P   GIG+A C++ +++A YYN I+ W+L+Y   SF   L
Sbjct: 136 ELALGQYHRNGCISIWRKICPIFKGIGYAICIIAFYIASYYNTIMAWALYYLISSFTDQL 195

Query: 178 PWDQCP---LVKNASHTFVEPE----CEQSSATTYYWYREALNI--SSSISESGGLNWKM 228
           PW  C       N ++ F E         +S    ++ R  L I  S  + + GG++W++
Sbjct: 196 PWTSCKNSWNTGNCTNYFSEDNITWTLHSTSPAEEFYTRHVLQIHRSKGLQDLGGISWQL 255

Query: 229 TICLLAAWVMVCLAMIKGIQSSGKVSMLE---PFLILLITI 266
            +C++  + ++  ++ KG+++SGKV  +    P++IL + +
Sbjct: 256 ALCIMLIFTVIYFSIWKGVKTSGKVVWVTATFPYIILSVLL 296


>gi|21361581 solute carrier family 6 (neurotransmitter transporter,
           GABA), member 13 [Homo sapiens]
          Length = 602

 Score =  180 bits (457), Expect = 1e-45
 Identities = 86/219 (39%), Positives = 126/219 (57%), Gaps = 12/219 (5%)

Query: 60  ERPAWNSKLQYILAQVGFSVGLGNVWRFPYLCQKNGGGAYLLPYLILLMVIGIPLFFLEL 119
           ER  WN+K++++L+  G  +GLGNVWRFPYLC KNGGGA+ +PYL+ L   GIP+F LE 
Sbjct: 31  ERGHWNNKMEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFIPYLVFLFTCGIPVFLLET 90

Query: 120 SVGQRIRRGSIGVWNYISPKLGGIGFASCVVCYFVALYYNVIIGWSLFYFSQSFQQPLPW 179
           ++GQ   +G +  W  I P   GIG+AS ++   + +YY +++ W+LFY   SF   LPW
Sbjct: 91  ALGQYTSQGGVTAWRKICPIFEGIGYASQMIVILLNVYYIIVLAWALFYLFSSFTIDLPW 150

Query: 180 DQCPLVKNASHTFVEPECEQS---------SATTYYWYREALNISSSISESGGLNWKMTI 230
             C    N  H     +   S         S    +W R  L IS  I   G L W++ +
Sbjct: 151 GGCYHEWNTEHCMEFQKTNGSLNGTSENATSPVIEFWERRVLKISDGIQHLGALRWELAL 210

Query: 231 CLLAAWVMVCLAMIKGIQSSGKV---SMLEPFLILLITI 266
           CLL AWV+    + KG++S+GKV   +   P+L+L++ +
Sbjct: 211 CLLLAWVICYFCIWKGVKSTGKVVYFTATFPYLMLVVLL 249


>gi|7657587 solute carrier family 6 (neurotransmitter transporter,
           GABA), member 11 [Homo sapiens]
          Length = 632

 Score =  176 bits (446), Expect = 2e-44
 Identities = 87/224 (38%), Positives = 128/224 (57%), Gaps = 20/224 (8%)

Query: 60  ERPAWNSKLQYILAQVGFSVGLGNVWRFPYLCQKNGGGAYLLPYLILLMVIGIPLFFLEL 119
           ER  WN+K++++L+  G  +GLGNVWRFPYLC KNGGGA+L+PY++  +  GIP+FFLE 
Sbjct: 49  ERGHWNNKVEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFLIPYVVFFICCGIPVFFLET 108

Query: 120 SVGQRIRRGSIGVWNYISPKLGGIGFASCVVCYFVALYYNVIIGWSLFYFSQSFQQPLPW 179
           ++GQ    G I  W  + P   GIG+A+ V+   + +YY +I+ W++FY S  F   LPW
Sbjct: 109 ALGQFTSEGGITCWRKVCPLFEGIGYATQVIEAHLNVYYIIILAWAIFYLSNCFTTELPW 168

Query: 180 DQCP--------------LVKNASHTFVEPECEQSSATTYYWYREALNISSSISESGGLN 225
             C                V N SH  ++     +S    +W    L IS  I   G L 
Sbjct: 169 ATCGHEWNTENCVEFQKLNVSNYSHVSLQ---NATSPVMEFWEHRVLAISDGIEHIGNLR 225

Query: 226 WKMTICLLAAWVMVCLAMIKGIQSSGKVSMLE---PFLILLITI 266
           W++ +CLLAAW +    + KG +S+GKV  +    P+++LLI +
Sbjct: 226 WELALCLLAAWTICYFCIWKGTKSTGKVVYVTATFPYIMLLILL 269


>gi|188528618 solute carrier family 6 (neurotransmitter transporter,
           GABA), member 1 [Homo sapiens]
          Length = 599

 Score =  175 bits (444), Expect = 4e-44
 Identities = 90/261 (34%), Positives = 142/261 (54%), Gaps = 10/261 (3%)

Query: 35  KTSELIVDGQEEKDTDVEEGSEVED--ERPAWNSKLQYILAQVGFSVGLGNVWRFPYLCQ 92
           + SE  V   + K   V+   +  D  +R  W  +  ++++ VG+++GLGNVWRFPYLC 
Sbjct: 16  EVSEAPVANDKPKTLVVKVQKKAADLPDRDTWKGRFDFLMSCVGYAIGLGNVWRFPYLCG 75

Query: 93  KNGGGAYLLPYLILLMVIGIPLFFLELSVGQRIRRGSIGVWNYISPKLGGIGFASCVVCY 152
           KNGGGA+L+PY + L+  G+PLF LE S+GQ    G +GVW  ++P   G+G A+ V+ +
Sbjct: 76  KNGGGAFLIPYFLTLIFAGVPLFLLECSLGQYTSIGGLGVWK-LAPMFKGVGLAAAVLSF 134

Query: 153 FVALYYNVIIGWSLFYFSQSFQQPLPWDQCPLVKNASHTF----VEPECEQSSATTYYWY 208
           ++ +YY VII W+++Y   SF   LPW QC    N    F    +      +SA   +W 
Sbjct: 135 WLNIYYIVIISWAIYYLYNSFTTTLPWKQCDNPWNTDRCFSNYSMVNTTNMTSAVVEFWE 194

Query: 209 REALNISSSISESGGLNWKMTICLLAAWVMVCLAMIKGIQSSGKV---SMLEPFLILLIT 265
           R    ++  + + G + W + I L  AW++V   + KG+  +GKV   S   P+++L+I 
Sbjct: 195 RNMHQMTDGLDKPGQIRWPLAITLAIAWILVYFCIWKGVGWTGKVVYFSATYPYIMLIIL 254

Query: 266 ISGFIPLSNSVTDFCGQITHN 286
               + L  +       IT N
Sbjct: 255 FFRGVTLPGAKEGILFYITPN 275


>gi|134304856 solute carrier family 6, member 7 [Homo sapiens]
          Length = 636

 Score =  174 bits (442), Expect = 6e-44
 Identities = 97/248 (39%), Positives = 138/248 (55%), Gaps = 20/248 (8%)

Query: 36  TSELIVDGQEEKDTDVEEGSEVEDERPAWNSKLQYILAQVGFSVGLGNVWRFPYLCQKNG 95
           T +L++   ++ D D++   +    R  W  KL ++L+ +G+ VGLGNVWRFPY    NG
Sbjct: 14  TPDLLMTPSDQGDVDLDV--DFAAHRGNWTGKLDFLLSCIGYCVGLGNVWRFPYRAYTNG 71

Query: 96  GGAYLLPYLILLMVIGIPLFFLELSVGQRIRRGSIGVWNYISPKLGGIGFASCVVCYFVA 155
           GGA+L+PY ++L + GIPLFFLELS+GQ    G + VW  ISP   G G A  ++   VA
Sbjct: 72  GGAFLVPYFLMLAICGIPLFFLELSLGQFSSLGPLAVWK-ISPLFKGAGAAMLLIVGLVA 130

Query: 156 LYYNVIIGWSLFYFSQSFQQPLPWDQCPLVKNASHTFVEPECEQS------------SAT 203
           +YYN+II + LFY   S    LPW+ C    N          +              S +
Sbjct: 131 IYYNMIIAYVLFYLFASLTSDLPWEHCGNWWNTELCLEHRVSKDGNGALPLNLTCTVSPS 190

Query: 204 TYYWYREALNI--SSSISESGGLNWKMTICLLAAWVMVCLAMIKGIQSSGKV---SMLEP 258
             YW R  L+I  S  I   G + W + +CLL AWV+V L ++KG++SSGKV   +   P
Sbjct: 191 EEYWSRYVLHIQGSQGIGSPGEIRWNLCLCLLLAWVIVFLCILKGVKSSGKVVYFTATFP 250

Query: 259 FLILLITI 266
           +LILL+ +
Sbjct: 251 YLILLMLL 258


>gi|67782317 solute carrier family 6 member 9 isoform 3 [Homo
           sapiens]
          Length = 633

 Score =  169 bits (428), Expect = 3e-42
 Identities = 87/233 (37%), Positives = 131/233 (56%), Gaps = 30/233 (12%)

Query: 60  ERPAWNSKLQYILAQVGFSVGLGNVWRFPYLCQKNGGGAYLLPYLILLMVIGIPLFFLEL 119
           +R  W ++++++L  VG++VGLGNVWRFPYLC +NGGGA++ PY I+L+  GIPLFF+EL
Sbjct: 26  KRGNWGNQIEFVLTSVGYAVGLGNVWRFPYLCYRNGGGAFMFPYFIMLIFCGIPLFFMEL 85

Query: 120 SVGQRIRRGSIGVWNYISPKLGGIGFASCVVCYFVALYYNVIIGWSLFYFSQSFQQPLPW 179
           S GQ   +G +GVW  ISP   G+G+   VV  ++ +YYNV+I  + +YF  S    LPW
Sbjct: 86  SFGQFASQGCLGVWR-ISPMFKGVGYGMMVVSTYIGIYYNVVICIAFYYFFSSMTHVLPW 144

Query: 180 DQC-------------------------PLVKNASHTFVEPECEQSSATTYYWYREALNI 214
             C                          L  N SH  +    +++S +  YW    L +
Sbjct: 145 AYCNNPWNTHDCAGVLDASNLTNGSRPAALPSNLSH-LLNHSLQRTSPSEEYWRLYVLKL 203

Query: 215 SSSISESGGLNWKMTICLLAAWVMVCLAMIKGIQSSGKV---SMLEPFLILLI 264
           S  I   G +   +  CL  +W++V L +I+G++SSGKV   +   P+++L I
Sbjct: 204 SDDIGNFGEVRLPLLGCLGVSWLVVFLCLIRGVKSSGKVVYFTATFPYVVLTI 256


>gi|67782315 solute carrier family 6 member 9 isoform 2 [Homo
           sapiens]
          Length = 706

 Score =  169 bits (428), Expect = 3e-42
 Identities = 87/233 (37%), Positives = 131/233 (56%), Gaps = 30/233 (12%)

Query: 60  ERPAWNSKLQYILAQVGFSVGLGNVWRFPYLCQKNGGGAYLLPYLILLMVIGIPLFFLEL 119
           +R  W ++++++L  VG++VGLGNVWRFPYLC +NGGGA++ PY I+L+  GIPLFF+EL
Sbjct: 99  KRGNWGNQIEFVLTSVGYAVGLGNVWRFPYLCYRNGGGAFMFPYFIMLIFCGIPLFFMEL 158

Query: 120 SVGQRIRRGSIGVWNYISPKLGGIGFASCVVCYFVALYYNVIIGWSLFYFSQSFQQPLPW 179
           S GQ   +G +GVW  ISP   G+G+   VV  ++ +YYNV+I  + +YF  S    LPW
Sbjct: 159 SFGQFASQGCLGVWR-ISPMFKGVGYGMMVVSTYIGIYYNVVICIAFYYFFSSMTHVLPW 217

Query: 180 DQC-------------------------PLVKNASHTFVEPECEQSSATTYYWYREALNI 214
             C                          L  N SH  +    +++S +  YW    L +
Sbjct: 218 AYCNNPWNTHDCAGVLDASNLTNGSRPAALPSNLSH-LLNHSLQRTSPSEEYWRLYVLKL 276

Query: 215 SSSISESGGLNWKMTICLLAAWVMVCLAMIKGIQSSGKV---SMLEPFLILLI 264
           S  I   G +   +  CL  +W++V L +I+G++SSGKV   +   P+++L I
Sbjct: 277 SDDIGNFGEVRLPLLGCLGVSWLVVFLCLIRGVKSSGKVVYFTATFPYVVLTI 329


>gi|67782313 solute carrier family 6 member 9 isoform 1 [Homo
           sapiens]
          Length = 652

 Score =  169 bits (428), Expect = 3e-42
 Identities = 87/233 (37%), Positives = 131/233 (56%), Gaps = 30/233 (12%)

Query: 60  ERPAWNSKLQYILAQVGFSVGLGNVWRFPYLCQKNGGGAYLLPYLILLMVIGIPLFFLEL 119
           +R  W ++++++L  VG++VGLGNVWRFPYLC +NGGGA++ PY I+L+  GIPLFF+EL
Sbjct: 45  KRGNWGNQIEFVLTSVGYAVGLGNVWRFPYLCYRNGGGAFMFPYFIMLIFCGIPLFFMEL 104

Query: 120 SVGQRIRRGSIGVWNYISPKLGGIGFASCVVCYFVALYYNVIIGWSLFYFSQSFQQPLPW 179
           S GQ   +G +GVW  ISP   G+G+   VV  ++ +YYNV+I  + +YF  S    LPW
Sbjct: 105 SFGQFASQGCLGVWR-ISPMFKGVGYGMMVVSTYIGIYYNVVICIAFYYFFSSMTHVLPW 163

Query: 180 DQC-------------------------PLVKNASHTFVEPECEQSSATTYYWYREALNI 214
             C                          L  N SH  +    +++S +  YW    L +
Sbjct: 164 AYCNNPWNTHDCAGVLDASNLTNGSRPAALPSNLSH-LLNHSLQRTSPSEEYWRLYVLKL 222

Query: 215 SSSISESGGLNWKMTICLLAAWVMVCLAMIKGIQSSGKV---SMLEPFLILLI 264
           S  I   G +   +  CL  +W++V L +I+G++SSGKV   +   P+++L I
Sbjct: 223 SDDIGNFGEVRLPLLGCLGVSWLVVFLCLIRGVKSSGKVVYFTATFPYVVLTI 275


>gi|92859670 solute carrier family 6 (neurotransmitter transporter,
           glycine), member 5 [Homo sapiens]
          Length = 797

 Score =  169 bits (428), Expect = 3e-42
 Identities = 94/266 (35%), Positives = 140/266 (52%), Gaps = 55/266 (20%)

Query: 49  TDVEEGSEVEDERPAWNSKLQYILAQVGFSVGLGNVWRFPYLCQKNGGGAYLLPYLILLM 108
           T  +E  +    R  W+SKL +IL+ VG++VGLGNVWRFPYL  +NGGGA+L+PYL++L 
Sbjct: 179 TQEDEQGDENKARGNWSSKLDFILSMVGYAVGLGNVWRFPYLAFQNGGGAFLIPYLMMLA 238

Query: 109 VIGIPLFFLELSVGQRIRRGSIGVWNYISPKLGGIGFASCVVCYFVALYYNVIIGWSLFY 168
           + G+P+FFLE+S+GQ   +G + VW  I P L G G A  ++   +A+YYNVII ++LFY
Sbjct: 239 LAGLPIFFLEVSLGQFASQGPVSVWKAI-PALQGCGIAMLIISVLIAIYYNVIICYTLFY 297

Query: 169 FSQSFQQPLPWDQCPLVKNASHTFVEPECEQS---------------------------- 200
              SF   LPW  C      ++ +  PEC+                              
Sbjct: 298 LFASFVSVLPWGSC------NNPWNTPECKDKTKLLLDSCVISDHPKIQIKNSTFCMTAY 351

Query: 201 -----------------SATTYYWYREALNISSSISESGGLNWKMTICLLAAWVMVCLAM 243
                            S +  Y+    L IS+ I   G + W + +CL  AWV+V  ++
Sbjct: 352 PNVTMVNFTSQANKTFVSGSEEYFKYFVLKISAGIEYPGEIRWPLALCLFLAWVIVYASL 411

Query: 244 IKGIQSSGKV---SMLEPFLILLITI 266
            KGI++SGKV   +   P+++L+I +
Sbjct: 412 AKGIKTSGKVVYFTATFPYVVLVILL 437


>gi|4557046 solute carrier family 6 member 2 [Homo sapiens]
          Length = 617

 Score =  166 bits (421), Expect = 2e-41
 Identities = 85/230 (36%), Positives = 129/230 (56%), Gaps = 31/230 (13%)

Query: 61  RPAWNSKLQYILAQVGFSVGLGNVWRFPYLCQKNGGGAYLLPYLILLMVIGIPLFFLELS 120
           R  W  K+ ++L+ VGF+V L NVWRFPYLC KNGGGA+L+PY + L++ G+PLF++EL+
Sbjct: 56  RETWGKKIDFLLSVVGFAVDLANVWRFPYLCYKNGGGAFLIPYTLFLIIAGMPLFYMELA 115

Query: 121 VGQRIRRGSIGVWNYISPKLGGIGFASCVVCYFVALYYNVIIGWSLFYFSQSFQQPLPWD 180
           +GQ  R G+  VW  I P   G+G+A  ++  +V  YYNVII WSL+Y   SF   LPW 
Sbjct: 116 LGQYNREGAATVWK-ICPFFKGVGYAVILIALYVGFYYNVIIAWSLYYLFSSFTLNLPWT 174

Query: 181 QCPLVKNASHTFVEPECEQ---------SSATTYYWYREA------------LNISSSIS 219
            C       HT+  P C            + T Y  Y+              L+ SS I 
Sbjct: 175 DC------GHTWNSPNCTDPKLLNGSVLGNHTKYSKYKFTPAAEFYERGVLHLHESSGIH 228

Query: 220 ESGGLNWKMTICLLAAWVMVCLAMIKGIQSSGKVSMLE---PFLILLITI 266
           + G   W++ +CL+   +++  ++ KG+++SGKV  +    P+ +L + +
Sbjct: 229 DIGLPQWQLLLCLMVVVIVLYFSLWKGVKTSGKVVWITATLPYFVLFVLL 278


>gi|4507041 solute carrier family 6 (neurotransmitter transporter,
           dopamine), member 3 [Homo sapiens]
          Length = 620

 Score =  164 bits (415), Expect = 8e-41
 Identities = 83/240 (34%), Positives = 136/240 (56%), Gaps = 30/240 (12%)

Query: 60  ERPAWNSKLQYILAQVGFSVGLGNVWRFPYLCQKNGGGAYLLPYLILLMVIGIPLFFLEL 119
           +R  W  K+ ++L+ +GF+V L NVWRFPYLC KNGGGA+L+PYL+ +++ G+PLF++EL
Sbjct: 59  DRETWGKKIDFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLVPYLLFMVIAGMPLFYMEL 118

Query: 120 SVGQRIRRGSIGVWNYISPKLGGIGFASCVVCYFVALYYNVIIGWSLFYFSQSFQQPLPW 179
           ++GQ  R G+ GVW  I P L G+GF   ++  +V  +YNVII W+L Y   SF   LPW
Sbjct: 119 ALGQFNREGAAGVWK-ICPILKGVGFTVILISLYVGFFYNVIIAWALHYLFSSFTTELPW 177

Query: 180 DQCPLVKNASHTFVEPECEQ------------------SSATTYYWYREALNI--SSSIS 219
             C      ++++  P C                    ++    Y+ R  L++  S  I 
Sbjct: 178 IHC------NNSWNSPNCSDAHPGDSSGDSSGLNDTFGTTPAAEYFERGVLHLHQSHGID 231

Query: 220 ESGGLNWKMTICLLAAWVMVCLAMIKGIQSSGKVSMLE---PFLILLITISGFIPLSNSV 276
           + G   W++T CL+   V++  ++ KG+++SGKV  +    P+++L   +   + L  ++
Sbjct: 232 DLGPPRWQLTACLVLVIVLLYFSLWKGVKTSGKVVWITATMPYVVLTALLLRGVTLPGAI 291


>gi|197276625 solute carrier family 6 (neurotransmitter transporter,
           taurine), member 6 isoform b [Homo sapiens]
          Length = 200

 Score =  148 bits (373), Expect = 6e-36
 Identities = 70/155 (45%), Positives = 95/155 (61%), Gaps = 13/155 (8%)

Query: 54  GSEVEDE-------RPAWNSKLQYILAQVGFSVGLGNVWRFPYLCQKNGGGAYLLPYLIL 106
           G+  EDE       R  W+SK+ ++L+  G  VGLGNVWRFPYLC KNGGGA+L+PY I 
Sbjct: 27  GTRPEDEAEGKPPQREKWSSKIDFVLSVAGGFVGLGNVWRFPYLCYKNGGGAFLIPYFIF 86

Query: 107 LMVIGIPLFFLELSVGQRIRRGSIGVWNYISPKLGGIGFASCVVCYFVALYYNVIIGWSL 166
           L   G+P+FFLE+ +GQ    G I  W  I P   GIG+AS V+   + +YY VI+ W+ 
Sbjct: 87  LFGSGLPVFFLEIIIGQYTSEGGITCWEKICPLFSGIGYASVVIVSLLNVYYIVILAWAT 146

Query: 167 FYFSQSFQQPLPWDQCPLVKNASHTFVEPECEQSS 201
           +Y  QSFQ+ LPW  C      +H++  P C + +
Sbjct: 147 YYLFQSFQKELPWAHC------NHSWNTPHCMEDT 175


>gi|218563758 solute carrier family 6 member 8 isoform 3 [Homo
           sapiens]
          Length = 520

 Score =  100 bits (249), Expect = 1e-21
 Identities = 50/168 (29%), Positives = 86/168 (51%), Gaps = 33/168 (19%)

Query: 125 IRRGSIGVWNYISPKLGGIGFASCVVCYFVALYYNVIIGWSLFYFSQSFQQPLPWDQCPL 184
           ++ GSI VWN I P   G+G+AS V+ ++   YY +++ W  +Y  +SF   LPW  C  
Sbjct: 1   MKAGSINVWN-ICPLFKGLGYASMVIVFYCNTYYIMVLAWGFYYLVKSFTTTLPWATC-- 57

Query: 185 VKNASHTFVEPEC-----------------------EQSSATTYYWYREALNISSSISES 221
                HT+  P+C                       ++ S    +W  + L +S  +   
Sbjct: 58  ----GHTWNTPDCVEIFRHEDCANASLANLTCDQLADRRSPVIEFWENKVLRLSGGLEVP 113

Query: 222 GGLNWKMTICLLAAWVMVCLAMIKGIQSSGKV---SMLEPFLILLITI 266
           G LNW++T+CLLA WV+V   + KG++S+GK+   +   P+++L++ +
Sbjct: 114 GALNWEVTLCLLACWVLVYFCVWKGVKSTGKIVYFTATFPYVVLVVLL 161


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.138    0.428 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,818,586
Number of Sequences: 37866
Number of extensions: 468132
Number of successful extensions: 1818
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 42
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 1706
Number of HSP's gapped (non-prelim): 84
length of query: 289
length of database: 18,247,518
effective HSP length: 101
effective length of query: 188
effective length of database: 14,423,052
effective search space: 2711533776
effective search space used: 2711533776
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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