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Search of human proteins with 11386199
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|11386199 poliovirus receptor-related 3 [Homo sapiens]
(549 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|11386199 poliovirus receptor-related 3 [Homo sapiens] 1122 0.0
gi|42560237 poliovirus receptor-related 1 isoform 1 [Homo sapiens] 235 9e-62
gi|42560231 poliovirus receptor-related 1 isoform 2 [Homo sapiens] 208 1e-53
gi|42560233 poliovirus receptor-related 1 isoform 3 [Homo sapiens] 205 1e-52
gi|222136611 poliovirus receptor-related 4 [Homo sapiens] 193 4e-49
gi|112789532 poliovirus receptor related 2 isoform delta precurs... 159 6e-39
gi|5360210 poliovirus receptor related 2 isoform alpha precursor... 157 2e-38
gi|209413732 poliovirus receptor isoform delta [Homo sapiens] 146 4e-35
gi|209413728 poliovirus receptor isoform beta [Homo sapiens] 146 4e-35
gi|209413726 poliovirus receptor isoform alpha [Homo sapiens] 146 4e-35
gi|209413730 poliovirus receptor isoform gamma [Homo sapiens] 144 3e-34
gi|148664190 immunoglobulin superfamily, member 4D isoform 1 [Ho... 118 2e-26
gi|148664211 immunoglobulin superfamily, member 4D isoform 2 [Ho... 103 3e-22
gi|54607031 immunoglobulin superfamily, member 4D [Homo sapiens] 88 2e-17
gi|187608363 cell adhesion molecule 3 isoform 2 [Homo sapiens] 82 2e-15
gi|11056046 cell adhesion molecule 3 isoform 1 [Homo sapiens] 80 5e-15
gi|21686977 cell adhesion molecule 4 [Homo sapiens] 73 6e-13
gi|90903245 CD200 antigen isoform b [Homo sapiens] 73 8e-13
gi|90903247 CD200 antigen isoform a precursor [Homo sapiens] 73 8e-13
gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens] 63 6e-10
gi|171460997 CD226 molecule precursor [Homo sapiens] 62 1e-09
gi|118572606 hemicentin 1 [Homo sapiens] 58 2e-08
gi|20127422 Down syndrome cell adhesion molecule isoform CHD2-42... 57 4e-08
gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens] 54 3e-07
gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens] 54 3e-07
gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens] 54 3e-07
gi|32699028 V-set and immunoglobulin domain containing 1 [Homo s... 54 3e-07
gi|11225258 myelin associated glycoprotein isoform a precursor [... 54 4e-07
gi|18104957 myelin associated glycoprotein isoform b precursor [... 54 4e-07
gi|26006461 kin of IRRE like 3 isoform 1 [Homo sapiens] 53 8e-07
>gi|11386199 poliovirus receptor-related 3 [Homo sapiens]
Length = 549
Score = 1122 bits (2901), Expect = 0.0
Identities = 549/549 (100%), Positives = 549/549 (100%)
Query: 1 MARTLRPSPLCPGGGKAQLSSASLLGAGLLLQPPTPPPLLLLLFPLLLFSRLCGALAGPI 60
MARTLRPSPLCPGGGKAQLSSASLLGAGLLLQPPTPPPLLLLLFPLLLFSRLCGALAGPI
Sbjct: 1 MARTLRPSPLCPGGGKAQLSSASLLGAGLLLQPPTPPPLLLLLFPLLLFSRLCGALAGPI 60
Query: 61 IVEPHVTAVWGKNVSLKCLIEVNETITQISWEKIHGKSSQTVAVHHPQYGFSVQGEYQGR 120
IVEPHVTAVWGKNVSLKCLIEVNETITQISWEKIHGKSSQTVAVHHPQYGFSVQGEYQGR
Sbjct: 61 IVEPHVTAVWGKNVSLKCLIEVNETITQISWEKIHGKSSQTVAVHHPQYGFSVQGEYQGR 120
Query: 121 VLFKNYSLNDATITLHNIGFSDSGKYICKAVTFPLGNAQSSTTVTVLVEPTVSLIKGPDS 180
VLFKNYSLNDATITLHNIGFSDSGKYICKAVTFPLGNAQSSTTVTVLVEPTVSLIKGPDS
Sbjct: 121 VLFKNYSLNDATITLHNIGFSDSGKYICKAVTFPLGNAQSSTTVTVLVEPTVSLIKGPDS 180
Query: 181 LIDGGNETVAAICIAATGKPVAHIDWEGDLGEMESTTTSFPNETATIISQYKLFPTRFAR 240
LIDGGNETVAAICIAATGKPVAHIDWEGDLGEMESTTTSFPNETATIISQYKLFPTRFAR
Sbjct: 181 LIDGGNETVAAICIAATGKPVAHIDWEGDLGEMESTTTSFPNETATIISQYKLFPTRFAR 240
Query: 241 GRRITCVVKHPALEKDIRYSFILDIQYAPEVSVTGYDGNWFVGRKGVNLKCNADANPPPF 300
GRRITCVVKHPALEKDIRYSFILDIQYAPEVSVTGYDGNWFVGRKGVNLKCNADANPPPF
Sbjct: 241 GRRITCVVKHPALEKDIRYSFILDIQYAPEVSVTGYDGNWFVGRKGVNLKCNADANPPPF 300
Query: 301 KSVWSRLDGQWPDGLLASDNTLHFVHPLTFNYSGVYICKVTNSLGQRSDQKVIYISDPPT 360
KSVWSRLDGQWPDGLLASDNTLHFVHPLTFNYSGVYICKVTNSLGQRSDQKVIYISDPPT
Sbjct: 301 KSVWSRLDGQWPDGLLASDNTLHFVHPLTFNYSGVYICKVTNSLGQRSDQKVIYISDPPT 360
Query: 361 TTTLQPTIQWHPSTADIEDLATEPKKLPFPLSTLATIKDDTIATIIASVVGGALFIVLVS 420
TTTLQPTIQWHPSTADIEDLATEPKKLPFPLSTLATIKDDTIATIIASVVGGALFIVLVS
Sbjct: 361 TTTLQPTIQWHPSTADIEDLATEPKKLPFPLSTLATIKDDTIATIIASVVGGALFIVLVS 420
Query: 421 VLAGIFCYRRRRTFRGDYFAKNYIPPSDMQKESQIDVLQQDELDSYPDSVKKENKNPVNN 480
VLAGIFCYRRRRTFRGDYFAKNYIPPSDMQKESQIDVLQQDELDSYPDSVKKENKNPVNN
Sbjct: 421 VLAGIFCYRRRRTFRGDYFAKNYIPPSDMQKESQIDVLQQDELDSYPDSVKKENKNPVNN 480
Query: 481 LIRKDYLEEPEKTQWNNVENLNRFERPMDYYEDLKMGMKFVSDEHYDENEDDLVSHVDGS 540
LIRKDYLEEPEKTQWNNVENLNRFERPMDYYEDLKMGMKFVSDEHYDENEDDLVSHVDGS
Sbjct: 481 LIRKDYLEEPEKTQWNNVENLNRFERPMDYYEDLKMGMKFVSDEHYDENEDDLVSHVDGS 540
Query: 541 VISRREWYV 549
VISRREWYV
Sbjct: 541 VISRREWYV 549
>gi|42560237 poliovirus receptor-related 1 isoform 1 [Homo sapiens]
Length = 517
Score = 235 bits (599), Expect = 9e-62
Identities = 161/492 (32%), Positives = 238/492 (48%), Gaps = 64/492 (13%)
Query: 86 ITQISWEKIHGKSSQTVAVHHPQYGFSVQGEYQGRVLFKNYSLNDATITLHNIGFSDSGK 145
ITQ++W+K S Q VA+++P G SV Y+ RV F S D TI L + D G
Sbjct: 62 ITQVTWQKSTNGSKQNVAIYNPSMGVSVLAPYRERVEFLRPSFTDGTIRLSRLELEDEGV 121
Query: 146 YICKAVTFPLGNAQSSTTVTVLVEPTVSLIKGPDSLIDG----GNETVAAICIAATGKPV 201
YIC+ TFP GN +S +TV+ +PT + I+G +++ ++ + A C +A GKP
Sbjct: 122 YICEFATFPTGNRESQLNLTVMAKPT-NWIEGTQAVLRAKKGQDDKVLVATCTSANGKPP 180
Query: 202 AHIDWEGDL-GEMESTTTSFPNETATIISQYKLFPTRFARGRRITCVVKHPALEKDIRYS 260
+ + WE L GE E PN T T+IS+Y+L P+R A + + C+V + + S
Sbjct: 181 SVVSWETRLKGEAEYQEIRNPNGTVTVISRYRLVPSREAHQQSLACIVNYHM--DRFKES 238
Query: 261 FILDIQYAPEVSVTGYDGNWFVGRKGVNLKCNADANPPPFKSVWSRLDGQWPDGLLASDN 320
L++QY PEV++ G+DGNW++ R V L C ADANPP + W+ L+G P G+ A +
Sbjct: 239 LTLNVQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWTTLNGSLPKGVEAQNR 298
Query: 321 TLHFVHPLTFNYSGVYICKVTNSLGQRSDQKVIYISDPPTTTTLQPTIQWHPSTADIEDL 380
TL F P+ ++ +G YIC+ TN +G RS Q + I++ P T P+ H A
Sbjct: 299 TLFFKGPINYSLAGTYICEATNPIGTRSGQVEVNITEFPYT----PSPPEHGRRAG---- 350
Query: 381 ATEPKKLPFPLSTLATIKDDTIATIIASVVGGALFIVLVSVLAGIFCYRRRR-TFRGDYF 439
P P T I V G++ +VL+ V + RRRR TF+GDY
Sbjct: 351 -------PVP-------------TAIIGGVAGSILLVLIVVGGIVVALRRRRHTFKGDYS 390
Query: 440 AKNYIPPSDMQKES--QIDVLQQDELDSYPDSVKKENKNPVNNLIRKDYLEEPEKTQWNN 497
K ++ + K Q L YPD E K L Y EE E+ +
Sbjct: 391 TKKHVYGNGYSKAGIPQHHPPMAQNL-QYPDDSDDEKK--AGPLGGSSYEEEEEEEEGGG 447
Query: 498 --------------------VENLNRFERPMDYYEDLKMGMKFVSDEHYDENEDDLVSHV 537
++ E D Y D +G ++ D + +++VS
Sbjct: 448 GGERKVGGPHPKYDEDAKRPYFTVDEAEARQDGYGDRTLGYQY--DPEQLDLAENMVSQN 505
Query: 538 DGSVISRREWYV 549
DGS IS++EWYV
Sbjct: 506 DGSFISKKEWYV 517
>gi|42560231 poliovirus receptor-related 1 isoform 2 [Homo sapiens]
Length = 458
Score = 208 bits (529), Expect = 1e-53
Identities = 108/279 (38%), Positives = 162/279 (58%), Gaps = 8/279 (2%)
Query: 86 ITQISWEKIHGKSSQTVAVHHPQYGFSVQGEYQGRVLFKNYSLNDATITLHNIGFSDSGK 145
ITQ++W+K S Q VA+++P G SV Y+ RV F S D TI L + D G
Sbjct: 62 ITQVTWQKSTNGSKQNVAIYNPSMGVSVLAPYRERVEFLRPSFTDGTIRLSRLELEDEGV 121
Query: 146 YICKAVTFPLGNAQSSTTVTVLVEPTVSLIKGPDSLIDG----GNETVAAICIAATGKPV 201
YIC+ TFP GN +S +TV+ +PT + I+G +++ ++ + A C +A GKP
Sbjct: 122 YICEFATFPTGNRESQLNLTVMAKPT-NWIEGTQAVLRAKKGQDDKVLVATCTSANGKPP 180
Query: 202 AHIDWEGDL-GEMESTTTSFPNETATIISQYKLFPTRFARGRRITCVVKHPALEKDIRYS 260
+ + WE L GE E PN T T+IS+Y+L P+R A + + C+V + + S
Sbjct: 181 SVVSWETRLKGEAEYQEIRNPNGTVTVISRYRLVPSREAHQQSLACIVNYHM--DRFKES 238
Query: 261 FILDIQYAPEVSVTGYDGNWFVGRKGVNLKCNADANPPPFKSVWSRLDGQWPDGLLASDN 320
L++QY PEV++ G+DGNW++ R V L C ADANPP + W+ L+G P G+ A +
Sbjct: 239 LTLNVQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWTTLNGSLPKGVEAQNR 298
Query: 321 TLHFVHPLTFNYSGVYICKVTNSLGQRSDQKVIYISDPP 359
TL F P+ ++ +G YIC+ TN +G RS Q + I++ P
Sbjct: 299 TLFFKGPINYSLAGTYICEATNPIGTRSGQVEVNITEKP 337
>gi|42560233 poliovirus receptor-related 1 isoform 3 [Homo sapiens]
Length = 352
Score = 205 bits (521), Expect = 1e-52
Identities = 107/276 (38%), Positives = 160/276 (57%), Gaps = 8/276 (2%)
Query: 86 ITQISWEKIHGKSSQTVAVHHPQYGFSVQGEYQGRVLFKNYSLNDATITLHNIGFSDSGK 145
ITQ++W+K S Q VA+++P G SV Y+ RV F S D TI L + D G
Sbjct: 62 ITQVTWQKSTNGSKQNVAIYNPSMGVSVLAPYRERVEFLRPSFTDGTIRLSRLELEDEGV 121
Query: 146 YICKAVTFPLGNAQSSTTVTVLVEPTVSLIKGPDSLIDG----GNETVAAICIAATGKPV 201
YIC+ TFP GN +S +TV+ +PT + I+G +++ ++ + A C +A GKP
Sbjct: 122 YICEFATFPTGNRESQLNLTVMAKPT-NWIEGTQAVLRAKKGQDDKVLVATCTSANGKPP 180
Query: 202 AHIDWEGDL-GEMESTTTSFPNETATIISQYKLFPTRFARGRRITCVVKHPALEKDIRYS 260
+ + WE L GE E PN T T+IS+Y+L P+R A + + C+V + + S
Sbjct: 181 SVVSWETRLKGEAEYQEIRNPNGTVTVISRYRLVPSREAHQQSLACIVNYHM--DRFKES 238
Query: 261 FILDIQYAPEVSVTGYDGNWFVGRKGVNLKCNADANPPPFKSVWSRLDGQWPDGLLASDN 320
L++QY PEV++ G+DGNW++ R V L C ADANPP + W+ L+G P G+ A +
Sbjct: 239 LTLNVQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWTTLNGSLPKGVEAQNR 298
Query: 321 TLHFVHPLTFNYSGVYICKVTNSLGQRSDQKVIYIS 356
TL F P+ ++ +G YIC+ TN +G RS Q + I+
Sbjct: 299 TLFFKGPINYSLAGTYICEATNPIGTRSGQVEVNIT 334
>gi|222136611 poliovirus receptor-related 4 [Homo sapiens]
Length = 510
Score = 193 bits (490), Expect = 4e-49
Identities = 141/491 (28%), Positives = 224/491 (45%), Gaps = 68/491 (13%)
Query: 36 PPPLLLLLFPLLLFSRLCGALAGPIIVEPHVTAVWGKNVSLKCLI--EVNETITQISWEK 93
P LLLL L F+ C A G + VT V G++ L C + E + Q++W +
Sbjct: 12 PEAWLLLLLLLASFTGRCPA--GELETSDVVTVVLGQDAKLPCFYRGDSGEQVGQVAWAR 69
Query: 94 IH-GKSSQTVAVHHPQYGFSVQGEYQGRVLFKNYSLN--DATITLHNIGFSDSGKYICKA 150
+ G+ +Q +A+ H +YG V Y+GRV N D ++ L N +D G+Y C+
Sbjct: 70 VDAGEGAQELALLHSKYGLHVSPAYEGRVEQPPPPRNPLDGSVLLRNAVQADEGEYECRV 129
Query: 151 VTFPLGNAQSSTTVTVLVEPTVSLIKGPDSLIDGGNETVAAICIAATGKPVAHIDWEGDL 210
TFP G+ Q+ + VLV P SL GP +L +G T+AA C A G P + W+ ++
Sbjct: 130 STFPAGSFQARLRLRVLVPPLPSLNPGP-ALEEGQGLTLAASC-TAEGSPAPSVTWDTEV 187
Query: 211 GEMESTTTSFPNETATIISQYKLFPTRFARGRRITCVVKHPALEKDIRYSFILDIQYAPE 270
S+ + + +A + S++ L P+R G+ +TCVV HP L +D R + IL + + E
Sbjct: 188 KGTTSSRSFKHSRSAAVTSEFHLVPSRSMNGQPLTCVVSHPGLLQDQRITHILHVSFLAE 247
Query: 271 VSVTGYDGN--WFVGRKGVNLKCNADANPPPFKSVWSRLDGQWPDGLLASDNTLHFVHPL 328
SV G + W +GR+G LKC ++ PPP + W+RLDG P G+ +TL F PL
Sbjct: 248 ASVRGLEDQNLWHIGREGAMLKCLSEGQPPPSYN-WTRLDGPLPSGVRVDGDTLGF-PPL 305
Query: 329 TFNYSGVYICKVTNSLGQRSDQKVIYISDPPTTTTLQPTIQWHPSTADIEDLATEPKKLP 388
T +SG+Y+C V+N R Q + + DP + Q +
Sbjct: 306 TTEHSGIYVCHVSNEFSSRDSQVTVDVLDPQEDSGKQVDLV------------------- 346
Query: 389 FPLSTLATIKDDTIATIIASVVGGALFIVLVSVLAGIFCYRRRRTFRGDYFAKNYIPPSD 448
+ + ++ V+ LF +LV V+ + Y RR + + Y
Sbjct: 347 ------------SASVVVVGVIAALLFCLLVVVVVLMSRYHRR---KAQQMTQKYEEELT 391
Query: 449 MQKESQIDVLQQDELD--------------SYPDSVKKENKNPVNNLIRKDYLEEPEKTQ 494
+ +E+ I L D +PDS+K + V + EEPE
Sbjct: 392 LTRENSIRRLHSHHTDPRSQPEESVGLRAEGHPDSLKDNSSCSVMS-------EEPEGRS 444
Query: 495 WNNVENLNRFE 505
++ + + E
Sbjct: 445 YSTLTTVREIE 455
>gi|112789532 poliovirus receptor related 2 isoform delta precursor
[Homo sapiens]
Length = 538
Score = 159 bits (402), Expect = 6e-39
Identities = 106/348 (30%), Positives = 166/348 (47%), Gaps = 27/348 (7%)
Query: 33 PPTPPPLLLLLFPLLLFSRL-CGALAGPIIVEPHVTAVWGKNVSLKCLI---EVNETITQ 88
PPTP LL+PLLL L GA + V P V G V L C + I+
Sbjct: 13 PPTP-----LLWPLLLLLLLETGAQDVRVQVLPEVRGQLGGTVELPCHLLPPVPGLYISL 67
Query: 89 ISWEKIHGKSS-QTVAVHHPQYGFSVQGEYQG--RVLFKNYS----------LNDATITL 135
++W++ ++ Q VA HP+ G S G R+ F + L DAT+ L
Sbjct: 68 VTWQRPDAPANHQNVAAFHPKMGPSFPSPKPGSERLSFVSAKQSTGQDTEAELQDATLAL 127
Query: 136 HNIGFSDSGKYICKAVTFPLGNAQSSTTVTVLVEPTVSLIKGPDSLIDGGNETVAAICIA 195
H + D G Y C+ TFP G+ + T + V+ +P + + T A+CI+
Sbjct: 128 HGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQA--EAQKVTFSQDPTTVALCIS 185
Query: 196 ATGKPVAHIDWEGDLG--EMESTTTSFPNETATIISQYKLFPTRFARGRRITCVVKHPAL 253
G+P A I W L E+ + T T+ S++ L P+ A G +TC V+H +
Sbjct: 186 KEGRPPARISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADGVTVTCKVEHESF 245
Query: 254 EKDIRYSFILDIQYAPEVSVTGYDGNWFVGRKGVNLKCNADANPPPFKSVWSRLDGQWPD 313
E+ L ++Y PEVS++GYD NW++GR L C+ +NP P WS G +P
Sbjct: 246 EEPALIPVTLSVRYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPTGYDWSTTSGTFPT 305
Query: 314 GLLASDNTLHFVHPLTFNYSGVYICKVTNSLGQRSDQKVIYISDPPTT 361
+A + L +H + ++ ++C VTN++G ++VI++ + P T
Sbjct: 306 SAVAQGSQL-VIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRETPNT 352
>gi|5360210 poliovirus receptor related 2 isoform alpha precursor
[Homo sapiens]
Length = 479
Score = 157 bits (397), Expect = 2e-38
Identities = 105/346 (30%), Positives = 165/346 (47%), Gaps = 27/346 (7%)
Query: 33 PPTPPPLLLLLFPLLLFSRL-CGALAGPIIVEPHVTAVWGKNVSLKCLI---EVNETITQ 88
PPTP LL+PLLL L GA + V P V G V L C + I+
Sbjct: 13 PPTP-----LLWPLLLLLLLETGAQDVRVQVLPEVRGQLGGTVELPCHLLPPVPGLYISL 67
Query: 89 ISWEKIHGKSS-QTVAVHHPQYGFSVQGEYQG--RVLFKNYS----------LNDATITL 135
++W++ ++ Q VA HP+ G S G R+ F + L DAT+ L
Sbjct: 68 VTWQRPDAPANHQNVAAFHPKMGPSFPSPKPGSERLSFVSAKQSTGQDTEAELQDATLAL 127
Query: 136 HNIGFSDSGKYICKAVTFPLGNAQSSTTVTVLVEPTVSLIKGPDSLIDGGNETVAAICIA 195
H + D G Y C+ TFP G+ + T + V+ +P + + T A+CI+
Sbjct: 128 HGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQA--EAQKVTFSQDPTTVALCIS 185
Query: 196 ATGKPVAHIDWEGDLG--EMESTTTSFPNETATIISQYKLFPTRFARGRRITCVVKHPAL 253
G+P A I W L E+ + T T+ S++ L P+ A G +TC V+H +
Sbjct: 186 KEGRPPARISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADGVTVTCKVEHESF 245
Query: 254 EKDIRYSFILDIQYAPEVSVTGYDGNWFVGRKGVNLKCNADANPPPFKSVWSRLDGQWPD 313
E+ L ++Y PEVS++GYD NW++GR L C+ +NP P WS G +P
Sbjct: 246 EEPALIPVTLSVRYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPTGYDWSTTSGTFPT 305
Query: 314 GLLASDNTLHFVHPLTFNYSGVYICKVTNSLGQRSDQKVIYISDPP 359
+A + L +H + ++ ++C VTN++G ++VI++ + P
Sbjct: 306 SAVAQGSQL-VIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRETP 350
Score = 29.3 bits (64), Expect = 9.8
Identities = 13/20 (65%), Positives = 16/20 (80%)
Query: 530 EDDLVSHVDGSVISRREWYV 549
EDD+ S +DGS+ISRR YV
Sbjct: 460 EDDMESQLDGSLISRRAVYV 479
>gi|209413732 poliovirus receptor isoform delta [Homo sapiens]
Length = 392
Score = 146 bits (369), Expect = 4e-35
Identities = 99/329 (30%), Positives = 154/329 (46%), Gaps = 16/329 (4%)
Query: 41 LLLFPLLLFSRLCGALAGPIIVEP-HVTAVWGKNVSLKCLIEVNET----ITQISWEKIH 95
LLL LL+ S ++ P V G +V+L C ++V ++Q++W + H
Sbjct: 11 LLLVALLVLSWPPPGTGDVVVQAPTQVPGFLGDSVTLPCYLQVPNMEVTHVSQLTWAR-H 69
Query: 96 GKSSQTVAVHH---PQYGFSVQGEYQGRVLFKNYSLNDATITLHNIGFSDSGKYICKAVT 152
G+S H P Y S + E+ L L +A++ + + D G Y C VT
Sbjct: 70 GESGSMAVFHQTQGPSYSESKRLEFVAARL--GAELRNASLRMFGLRVEDEGNYTCLFVT 127
Query: 153 FPLGNAQSSTTVTVLVEPTVSLIKGPDSLIDGGNETVAAICIAATGKPVAHIDWEGDLGE 212
FP G+ + VL +P + L G A C++ G+P A I W DLG
Sbjct: 128 FPQGSRSVDIWLRVLAKPQNTAEVQKVQLT--GEPVPMARCVSTGGRPPAQITWHSDLGG 185
Query: 213 MESTTT--SFPNETATIISQYKLFPTRFARGRRITCVVKHPALEKDIRYSFILDIQYAPE 270
M +T+ F + T T+ S + L P+ G+ +TC V+H + EK + L + Y PE
Sbjct: 186 MPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHESFEKPQLLTVNLTVYYPPE 245
Query: 271 VSVTGYDGNWFVGRKGVNLKCNADANPPPFKSVWSRLDGQWPDGLLASDNTLHFVHPLTF 330
VS++GYD NW++G+ L C+A +NP P WS G P +A L + P+
Sbjct: 246 VSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWSTTMGPLPPFAVAQGAQL-LIRPVDK 304
Query: 331 NYSGVYICKVTNSLGQRSDQKVIYISDPP 359
+ IC VTN+LG R + + + + P
Sbjct: 305 PINTTLICNVTNALGARQAELTVQVKEGP 333
>gi|209413728 poliovirus receptor isoform beta [Homo sapiens]
Length = 372
Score = 146 bits (369), Expect = 4e-35
Identities = 99/329 (30%), Positives = 154/329 (46%), Gaps = 16/329 (4%)
Query: 41 LLLFPLLLFSRLCGALAGPIIVEP-HVTAVWGKNVSLKCLIEVNET----ITQISWEKIH 95
LLL LL+ S ++ P V G +V+L C ++V ++Q++W + H
Sbjct: 11 LLLVALLVLSWPPPGTGDVVVQAPTQVPGFLGDSVTLPCYLQVPNMEVTHVSQLTWAR-H 69
Query: 96 GKSSQTVAVHH---PQYGFSVQGEYQGRVLFKNYSLNDATITLHNIGFSDSGKYICKAVT 152
G+S H P Y S + E+ L L +A++ + + D G Y C VT
Sbjct: 70 GESGSMAVFHQTQGPSYSESKRLEFVAARL--GAELRNASLRMFGLRVEDEGNYTCLFVT 127
Query: 153 FPLGNAQSSTTVTVLVEPTVSLIKGPDSLIDGGNETVAAICIAATGKPVAHIDWEGDLGE 212
FP G+ + VL +P + L G A C++ G+P A I W DLG
Sbjct: 128 FPQGSRSVDIWLRVLAKPQNTAEVQKVQLT--GEPVPMARCVSTGGRPPAQITWHSDLGG 185
Query: 213 MESTTT--SFPNETATIISQYKLFPTRFARGRRITCVVKHPALEKDIRYSFILDIQYAPE 270
M +T+ F + T T+ S + L P+ G+ +TC V+H + EK + L + Y PE
Sbjct: 186 MPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHESFEKPQLLTVNLTVYYPPE 245
Query: 271 VSVTGYDGNWFVGRKGVNLKCNADANPPPFKSVWSRLDGQWPDGLLASDNTLHFVHPLTF 330
VS++GYD NW++G+ L C+A +NP P WS G P +A L + P+
Sbjct: 246 VSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWSTTMGPLPPFAVAQGAQL-LIRPVDK 304
Query: 331 NYSGVYICKVTNSLGQRSDQKVIYISDPP 359
+ IC VTN+LG R + + + + P
Sbjct: 305 PINTTLICNVTNALGARQAELTVQVKEGP 333
>gi|209413726 poliovirus receptor isoform alpha [Homo sapiens]
Length = 417
Score = 146 bits (369), Expect = 4e-35
Identities = 99/329 (30%), Positives = 154/329 (46%), Gaps = 16/329 (4%)
Query: 41 LLLFPLLLFSRLCGALAGPIIVEP-HVTAVWGKNVSLKCLIEVNET----ITQISWEKIH 95
LLL LL+ S ++ P V G +V+L C ++V ++Q++W + H
Sbjct: 11 LLLVALLVLSWPPPGTGDVVVQAPTQVPGFLGDSVTLPCYLQVPNMEVTHVSQLTWAR-H 69
Query: 96 GKSSQTVAVHH---PQYGFSVQGEYQGRVLFKNYSLNDATITLHNIGFSDSGKYICKAVT 152
G+S H P Y S + E+ L L +A++ + + D G Y C VT
Sbjct: 70 GESGSMAVFHQTQGPSYSESKRLEFVAARL--GAELRNASLRMFGLRVEDEGNYTCLFVT 127
Query: 153 FPLGNAQSSTTVTVLVEPTVSLIKGPDSLIDGGNETVAAICIAATGKPVAHIDWEGDLGE 212
FP G+ + VL +P + L G A C++ G+P A I W DLG
Sbjct: 128 FPQGSRSVDIWLRVLAKPQNTAEVQKVQLT--GEPVPMARCVSTGGRPPAQITWHSDLGG 185
Query: 213 MESTTT--SFPNETATIISQYKLFPTRFARGRRITCVVKHPALEKDIRYSFILDIQYAPE 270
M +T+ F + T T+ S + L P+ G+ +TC V+H + EK + L + Y PE
Sbjct: 186 MPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHESFEKPQLLTVNLTVYYPPE 245
Query: 271 VSVTGYDGNWFVGRKGVNLKCNADANPPPFKSVWSRLDGQWPDGLLASDNTLHFVHPLTF 330
VS++GYD NW++G+ L C+A +NP P WS G P +A L + P+
Sbjct: 246 VSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWSTTMGPLPPFAVAQGAQL-LIRPVDK 304
Query: 331 NYSGVYICKVTNSLGQRSDQKVIYISDPP 359
+ IC VTN+LG R + + + + P
Sbjct: 305 PINTTLICNVTNALGARQAELTVQVKEGP 333
>gi|209413730 poliovirus receptor isoform gamma [Homo sapiens]
Length = 364
Score = 144 bits (362), Expect = 3e-34
Identities = 98/325 (30%), Positives = 152/325 (46%), Gaps = 16/325 (4%)
Query: 41 LLLFPLLLFSRLCGALAGPIIVEP-HVTAVWGKNVSLKCLIEVNET----ITQISWEKIH 95
LLL LL+ S ++ P V G +V+L C ++V ++Q++W + H
Sbjct: 11 LLLVALLVLSWPPPGTGDVVVQAPTQVPGFLGDSVTLPCYLQVPNMEVTHVSQLTWAR-H 69
Query: 96 GKSSQTVAVHH---PQYGFSVQGEYQGRVLFKNYSLNDATITLHNIGFSDSGKYICKAVT 152
G+S H P Y S + E+ L L +A++ + + D G Y C VT
Sbjct: 70 GESGSMAVFHQTQGPSYSESKRLEFVAARL--GAELRNASLRMFGLRVEDEGNYTCLFVT 127
Query: 153 FPLGNAQSSTTVTVLVEPTVSLIKGPDSLIDGGNETVAAICIAATGKPVAHIDWEGDLGE 212
FP G+ + VL +P + L G A C++ G+P A I W DLG
Sbjct: 128 FPQGSRSVDIWLRVLAKPQNTAEVQKVQLT--GEPVPMARCVSTGGRPPAQITWHSDLGG 185
Query: 213 MESTTT--SFPNETATIISQYKLFPTRFARGRRITCVVKHPALEKDIRYSFILDIQYAPE 270
M +T+ F + T T+ S + L P+ G+ +TC V+H + EK + L + Y PE
Sbjct: 186 MPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHESFEKPQLLTVNLTVYYPPE 245
Query: 271 VSVTGYDGNWFVGRKGVNLKCNADANPPPFKSVWSRLDGQWPDGLLASDNTLHFVHPLTF 330
VS++GYD NW++G+ L C+A +NP P WS G P +A L + P+
Sbjct: 246 VSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWSTTMGPLPPFAVAQGAQL-LIRPVDK 304
Query: 331 NYSGVYICKVTNSLGQRSDQKVIYI 355
+ IC VTN+LG R + + +
Sbjct: 305 PINTTLICNVTNALGARQAELTVQV 329
>gi|148664190 immunoglobulin superfamily, member 4D isoform 1 [Homo
sapiens]
Length = 442
Score = 118 bits (295), Expect = 2e-26
Identities = 109/437 (24%), Positives = 194/437 (44%), Gaps = 37/437 (8%)
Query: 8 SPLCPGGGKAQLSSASLLGAGLLLQPPTPPPLLLLLFPLLLFSRLCGALAGPIIVEPHVT 67
S + P G + ++A+ GL L+ LLLLLF + L G + VT
Sbjct: 3 SVVLPSGSQCAAAAAAAAPPGLRLR------LLLLLFSA---AALIPTGDGQNLFTKDVT 53
Query: 68 AVWGKNVSLKCLIEVNETITQISWEKIHGKSSQTVAVHHPQYGFSVQGEYQGRVLFKNYS 127
+ G+ ++ C +VN++ + ++ + QT+ Y + R N+S
Sbjct: 54 VIEGEVATISC--QVNKSDDSVI--QLLNPNRQTI------YFRDFRPLKDSRFQLLNFS 103
Query: 128 LNDATITLHNIGFSDSGKYICKAVTFPLGNAQSSTTVTVLVEPTVSLIK-GPDSLIDGGN 186
++ ++L N+ SD G+Y C+ T P +S TT+TVLV P +I D+ ++G
Sbjct: 104 SSELKVSLTNVSISDEGRYFCQLYTDP--PQESYTTITVLVPPRNLMIDIQKDTAVEG-- 159
Query: 187 ETVAAICIAATGKPVAHIDW-EGDLGEMESTTTSFPNETATIISQYKLFPTRFARGRRIT 245
E + C A KP I W +G+ + ++ T+ SQ L + G +
Sbjct: 160 EEIEVNCTAMASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPVI 219
Query: 246 CVVKHPALEKDIRYSFILDIQYAPEVSVTGYDGNWFVGRKG--VNLKCNADANPPPFKSV 303
C V+HPA+ +++ L++QY P+V + + R+G + L C A P P
Sbjct: 220 CQVEHPAVTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVT 279
Query: 304 WSRLDGQWPDGLLASDNTLHFVHPLTFNYSGVYICKVTNSLGQRSDQKVIYISDPPTTTT 363
W R+D + P + S L F++ L +G Y C+ +N +G+ ++Y+ DPPTT
Sbjct: 280 WVRVDDEMPQHAVLSGPNL-FINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDPPTTIP 338
Query: 364 LQPTIQWHPSTADIEDLATEPKKLPFPLSTLATIKDDTIATIIASVVGGALFIVLVSVLA 423
P T T + ++ ++ +I + +V+GG + +V+ ++L
Sbjct: 339 --------PPTTTTTTTTTTTTTILTIITDSRAGEEGSIRAVDHAVIGGVVAVVVFAMLC 390
Query: 424 GIFCYRRR-RTFRGDYF 439
+ R +G YF
Sbjct: 391 LLIILGRYFARHKGTYF 407
>gi|148664211 immunoglobulin superfamily, member 4D isoform 2 [Homo
sapiens]
Length = 414
Score = 103 bits (258), Expect = 3e-22
Identities = 92/354 (25%), Positives = 161/354 (45%), Gaps = 28/354 (7%)
Query: 8 SPLCPGGGKAQLSSASLLGAGLLLQPPTPPPLLLLLFPLLLFSRLCGALAGPIIVEPHVT 67
S + P G + ++A+ GL L+ LLLLLF + L G + VT
Sbjct: 3 SVVLPSGSQCAAAAAAAAPPGLRLR------LLLLLFSA---AALIPTGDGQNLFTKDVT 53
Query: 68 AVWGKNVSLKCLIEVNETITQISWEKIHGKSSQTVAVHHPQYGFSVQGEYQGRVLFKNYS 127
+ G+ ++ C +VN++ + ++ + QT+ Y + R N+S
Sbjct: 54 VIEGEVATISC--QVNKSDDSVI--QLLNPNRQTI------YFRDFRPLKDSRFQLLNFS 103
Query: 128 LNDATITLHNIGFSDSGKYICKAVTFPLGNAQSSTTVTVLVEPTVSLIK-GPDSLIDGGN 186
++ ++L N+ SD G+Y C+ T P +S TT+TVLV P +I D+ ++G
Sbjct: 104 SSELKVSLTNVSISDEGRYFCQLYTDP--PQESYTTITVLVPPRNLMIDIQKDTAVEG-- 159
Query: 187 ETVAAICIAATGKPVAHIDW-EGDLGEMESTTTSFPNETATIISQYKLFPTRFARGRRIT 245
E + C A KP I W +G+ + ++ T+ SQ L + G +
Sbjct: 160 EEIEVNCTAMASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPVI 219
Query: 246 CVVKHPALEKDIRYSFILDIQYAPEVSVTGYDGNWFVGRKG--VNLKCNADANPPPFKSV 303
C V+HPA+ +++ L++QY P+V + + R+G + L C A P P
Sbjct: 220 CQVEHPAVTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVT 279
Query: 304 WSRLDGQWPDGLLASDNTLHFVHPLTFNYSGVYICKVTNSLGQRSDQKVIYISD 357
W R+D + P + S L F++ L +G Y C+ +N +G+ ++Y+ D
Sbjct: 280 WVRVDDEMPQHAVLSGPNL-FINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYD 332
>gi|54607031 immunoglobulin superfamily, member 4D [Homo sapiens]
Length = 437
Score = 87.8 bits (216), Expect = 2e-17
Identities = 94/396 (23%), Positives = 168/396 (42%), Gaps = 39/396 (9%)
Query: 58 GPIIVEPHVTAVWGKNVSLKCLIEVNETITQISWEKIHGKSSQTVAVHHPQYGFSVQGEY 117
G + +VT V G L C ++ N+ T + W + QT+ Y +
Sbjct: 26 GQFPLTQNVTVVEGGTAILTCRVDQNDN-TSLQWSN---PAQQTL------YFDDKKALR 75
Query: 118 QGRVLFKNYSLNDATITLHNIGFSDSGKYICKAVTFPLGNAQSSTTVTVLVEPTVSLIKG 177
R+ S ++ +I++ ++ SD G+Y C T P+ S +TVL P I G
Sbjct: 76 DNRIELVRASWHELSISVSDVSLSDEGQYTCSLFTMPVKT--SKAYLTVLGVPEKPQISG 133
Query: 178 PDSLIDGGNETVAAICIAATGKPVAHIDW---EGDLGEMESTTTSFPN-ETATIISQYKL 233
S + G + + C + KP A I W + ++ +++ N +T T+ S
Sbjct: 134 FSSPVMEG-DLMQLTCKTSGSKPAADIRWFKNDKEIKDVKYLKEEDANRKTFTVSSTLDF 192
Query: 234 FPTRFARGRRITCVVKHPALEKDIRYSF-ILDIQYAPEVSVTGYDGNWFVGRKGVNLKCN 292
R G + C V H +L + + +L+I Y P V + G+ + L C
Sbjct: 193 RVDRSDDGVAVICRVDHESLNATPQVAMQVLEIHYTPSVKIIPSTPFPQEGQPLI-LTCE 251
Query: 293 ADANPPPFKSVWSRLDGQWPDG--LLASDNTLHFVHPLTFNYSGVYICKVTNSLGQRSDQ 350
+ P P +W++ G+ PD ++ S L+ + L +G Y C+ TN++GQ S +
Sbjct: 252 SKGKPLPEPVLWTKDGGELPDPDRMVVSGRELNILF-LNKTDNGTYRCEATNTIGQSSAE 310
Query: 351 KVIYISDPPTT---TTLQPTIQWHPSTADIEDLATEPKKLPFPLSTLATIKDDTIA---- 403
V+ + D P T TT+ P++ T + + P +T ++I+D
Sbjct: 311 YVLIVHDVPNTLLPTTIIPSLTTATVTTTVAITTS-----PTTSATTSSIRDPNALAGQN 365
Query: 404 ----TIIASVVGGALFIVLVSV-LAGIFCYRRRRTF 434
+I +V +F+ L S+ L G + R + T+
Sbjct: 366 GPDHALIGGIVAVVVFVTLCSIFLLGRYLARHKGTY 401
>gi|187608363 cell adhesion molecule 3 isoform 2 [Homo sapiens]
Length = 398
Score = 81.6 bits (200), Expect = 2e-15
Identities = 87/333 (26%), Positives = 142/333 (42%), Gaps = 29/333 (8%)
Query: 38 PLLLLLFPLLLFSRLCGALAGPIIVEPHV-------TAVWGKNVSLKCLIEVNETITQIS 90
P LL LLLF+ C A G + + T V G V LKC ++ +E + +
Sbjct: 4 PAASLLLLLLLFA-CCWAPGGANLSQDDSQPWTSDETVVAGGTVVLKCQVKDHED-SSLQ 61
Query: 91 WEKIHGKSSQTVAVHHPQYGFSVQGEYQGRVLFKNYSLNDATITLHNIGFSDSGKYICKA 150
W + QT+ Y + R+ + ++ +I++ N+ +D G+Y C
Sbjct: 62 WSN---PAQQTL------YFGEKRALRDNRIQLVTSTPHELSISISNVALADEGEYTCSI 112
Query: 151 VTFPLGNAQSSTTVTVLVEPTVSLIKGPDSLIDGGNETVAAICIAATGKPVAHIDWEGDL 210
T P+ A+S VTVL P +I G S + +T C ++ KP A + W
Sbjct: 113 FTMPVRTAKS--LVTVLGIPQKPIITGYKSSL-REKDTATLNCQSSGSKPAARLTWRKGD 169
Query: 211 GEMESTTTSF---PN-ETATIISQYKLFPTRFARGRRITCVVKHPALE-KDIRYSFILDI 265
E+ T PN +T T+ S TR G I C V H +L+ D S +++
Sbjct: 170 QELHGEPTRIQEDPNGKTFTVSSSVTFQVTREDDGASIVCSVNHESLKGADRSTSQRIEV 229
Query: 266 QYAPEVSVTGYDGNWFVGRKGVNLKCNADANPPPFKSVWSRLDGQWPDGLLASDNTLHFV 325
Y P + + G+K + L C NP P + +W + +G P + ++ L F
Sbjct: 230 LYTPTAMIRPDPPHPREGQK-LLLHCEGRGNPVPQQYLWEK-EGSVPPLKMTQESALIFP 287
Query: 326 HPLTFNYSGVYICKVTNSLGQRSDQKVIYISDP 358
L + SG Y C T+++G + ++DP
Sbjct: 288 F-LNKSDSGTYGCTATSNMGSYKAYYTLNVNDP 319
>gi|11056046 cell adhesion molecule 3 isoform 1 [Homo sapiens]
Length = 432
Score = 80.1 bits (196), Expect = 5e-15
Identities = 77/297 (25%), Positives = 129/297 (43%), Gaps = 21/297 (7%)
Query: 67 TAVWGKNVSLKCLIEVNETITQISWEKIHGKSSQTVAVHHPQYGFSVQGEYQGRVLFKNY 126
T V G V LKC ++ +E + + W + QT+ Y + R+
Sbjct: 73 TVVAGGTVVLKCQVKDHED-SSLQWSN---PAQQTL------YFGEKRALRDNRIQLVTS 122
Query: 127 SLNDATITLHNIGFSDSGKYICKAVTFPLGNAQSSTTVTVLVEPTVSLIKGPDSLIDGGN 186
+ ++ +I++ N+ +D G+Y C T P+ A+S VTVL P +I G S +
Sbjct: 123 TPHELSISISNVALADEGEYTCSIFTMPVRTAKS--LVTVLGIPQKPIITGYKSSL-REK 179
Query: 187 ETVAAICIAATGKPVAHIDWEGDLGEMESTTTSF---PN-ETATIISQYKLFPTRFARGR 242
+T C ++ KP A + W E+ T PN +T T+ S TR G
Sbjct: 180 DTATLNCQSSGSKPAARLTWRKGDQELHGEPTRIQEDPNGKTFTVSSSVTFQVTREDDGA 239
Query: 243 RITCVVKHPALE-KDIRYSFILDIQYAPEVSVTGYDGNWFVGRKGVNLKCNADANPPPFK 301
I C V H +L+ D S +++ Y P + + G+K + L C NP P +
Sbjct: 240 SIVCSVNHESLKGADRSTSQRIEVLYTPTAMIRPDPPHPREGQK-LLLHCEGRGNPVPQQ 298
Query: 302 SVWSRLDGQWPDGLLASDNTLHFVHPLTFNYSGVYICKVTNSLGQRSDQKVIYISDP 358
+W + +G P + ++ L F L + SG Y C T+++G + ++DP
Sbjct: 299 YLWEK-EGSVPPLKMTQESALIFPF-LNKSDSGTYGCTATSNMGSYKAYYTLNVNDP 353
>gi|21686977 cell adhesion molecule 4 [Homo sapiens]
Length = 388
Score = 73.2 bits (178), Expect = 6e-13
Identities = 74/334 (22%), Positives = 133/334 (39%), Gaps = 31/334 (9%)
Query: 46 LLLFSRLCGALAGPIIVEPHVTAVWGKNVSLKCLIEVNETITQISWEKIHGKSSQTVAVH 105
LLL++ G AG + +VT G + C ++H V +
Sbjct: 12 LLLWAAAAGPGAGQEVQTENVTVAEGGVAEITC--------------RLHQYDGSIVVIQ 57
Query: 106 HPQ----YGFSVQGEYQGRVLFKNYSLNDATITLHNIGFSDSGKYICKAVTFPLGNAQSS 161
+P + + R + +S I L + D G Y C+ T +
Sbjct: 58 NPARQTLFFNGTRALKDERFQLEEFSPRRVRIRLSDARLEDEGGYFCQLYTEDTHH--QI 115
Query: 162 TTVTVLVEPTVSLIKGPDSLIDGGNETVAAICIAATGKPVAHIDWEGDLGEMESTTTSFP 221
T+TVLV P +++ + ++GG V C+ +P A + W D E++ ++S
Sbjct: 116 ATLTVLVAPENPVVEVREQAVEGGE--VELSCLVPRSRPAATLRWYRDRKELKGVSSSQE 173
Query: 222 N-ETATIISQYKLFPTRFARGRRITCVVKHPALEK--DIRYSFILDIQYAPEVSVTGYDG 278
N + ++ S + R G I C ++ AL + ++LD+QY+P +
Sbjct: 174 NGKVWSVASTVRFRVDRKDDGGIIICEAQNQALPSGHSKQTQYVLDVQYSPTARIHASQA 233
Query: 279 NWFVGRKG--VNLKCNADANPPPFKSVWSRLDGQWPDGLLASDNTLHFVHPLTFNYSGVY 336
V R+G + L C NP P + W+R + P+ A TL ++ + +G Y
Sbjct: 234 ---VVREGDTLVLTCAVTGNPRPNQIRWNRGNESLPERAEAVGETLTLPGLVSAD-NGTY 289
Query: 337 ICKVTNSLGQRSDQKVIYISDPPTTTTLQPTIQW 370
C+ +N G V+ + DP Q ++ +
Sbjct: 290 TCEASNKHGHARALYVLVVYDPGAVVEAQTSVPY 323
>gi|90903245 CD200 antigen isoform b [Homo sapiens]
Length = 294
Score = 72.8 bits (177), Expect = 8e-13
Identities = 48/186 (25%), Positives = 82/186 (44%), Gaps = 9/186 (4%)
Query: 75 SLKCLIEVNETITQISWEKIHGKSSQTVAVHHPQYGFSVQGEYQGRVLFKNYSLNDATIT 134
SLKC ++ + ++W+K S + + +G +Q Y+ ++ L ++TIT
Sbjct: 73 SLKCSLQNAQEALIVTWQKKKAVSPENMVTFSENHGVVIQPAYKDKINITQLGLQNSTIT 132
Query: 135 LHNIGFSDSGKYICKAVTFPLGNAQSSTTVTVLVEPTVSLIKGPDSLIDGGNETVAAICI 194
NI D G Y+C TF G + +TV V+P VSL +E I
Sbjct: 133 FWNITLEDEGCYMCLFNTFGFGKISGTACLTVYVQPIVSLHY-------KFSEDHLNITC 185
Query: 195 AATGKPVAHIDWEGDLGEMESTTT--SFPNETATIISQYKLFPTRFARGRRITCVVKHPA 252
+AT +P + W+ +E++T S PN T ++ S + + G+ + C V H
Sbjct: 186 SATARPAPMVFWKVPRSGIENSTVTLSHPNGTTSVTSILHIKDPKNQVGKEVICQVLHLG 245
Query: 253 LEKDIR 258
D +
Sbjct: 246 TVTDFK 251
>gi|90903247 CD200 antigen isoform a precursor [Homo sapiens]
Length = 269
Score = 72.8 bits (177), Expect = 8e-13
Identities = 48/186 (25%), Positives = 82/186 (44%), Gaps = 9/186 (4%)
Query: 75 SLKCLIEVNETITQISWEKIHGKSSQTVAVHHPQYGFSVQGEYQGRVLFKNYSLNDATIT 134
SLKC ++ + ++W+K S + + +G +Q Y+ ++ L ++TIT
Sbjct: 48 SLKCSLQNAQEALIVTWQKKKAVSPENMVTFSENHGVVIQPAYKDKINITQLGLQNSTIT 107
Query: 135 LHNIGFSDSGKYICKAVTFPLGNAQSSTTVTVLVEPTVSLIKGPDSLIDGGNETVAAICI 194
NI D G Y+C TF G + +TV V+P VSL +E I
Sbjct: 108 FWNITLEDEGCYMCLFNTFGFGKISGTACLTVYVQPIVSLHY-------KFSEDHLNITC 160
Query: 195 AATGKPVAHIDWEGDLGEMESTTT--SFPNETATIISQYKLFPTRFARGRRITCVVKHPA 252
+AT +P + W+ +E++T S PN T ++ S + + G+ + C V H
Sbjct: 161 SATARPAPMVFWKVPRSGIENSTVTLSHPNGTTSVTSILHIKDPKNQVGKEVICQVLHLG 220
Query: 253 LEKDIR 258
D +
Sbjct: 221 TVTDFK 226
>gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens]
Length = 4391
Score = 63.2 bits (152), Expect = 6e-10
Identities = 95/400 (23%), Positives = 159/400 (39%), Gaps = 74/400 (18%)
Query: 1 MARTLRPSPLCPGGGKAQLSSAS-LLGAGLL--LQPPTPPPLLLLLFPLLLFSRLCGALA 57
+ R + SP G Q++ +S L A +L ++P +P P+ LA
Sbjct: 2877 LLRLNQVSPADSGEYSCQVTGSSGTLEASVLVTIEPSSPGPIP------------APGLA 2924
Query: 58 GPIIVEP---HVTAVWGKNVSLKCLIEVNETITQISWEKIHGKSSQTVAVHHPQYGFSVQ 114
PI +E HVT G+ + L C++ + Q++W K G ++ H +G
Sbjct: 2925 QPIYIEASSSHVTE--GQTLDLNCVVP-GQAHAQVTWYKRGG----SLPARHQTHG---- 2973
Query: 115 GEYQGRVLFKNYSLNDATITLHNIGFSDSGKYICKAVTFPLGNAQSSTTVTV-------- 166
+ + LH + +DSG+Y+C+A + P ++S TVTV
Sbjct: 2974 ----------------SQLRLHLVSPADSGEYVCRAASGPGPEQEASFTVTVPPSEGSSY 3017
Query: 167 -LVEPTVSLIKGPDSLIDGGNETVAAICIAATGKPVAHIDWEGDLGEMESTTTSFPNETA 225
L P +S I P S + G + + C+ G ++W+ E+E PN
Sbjct: 3018 RLRSPVIS-IDPPSSTVQQGQD-ASFKCLIHDGAAPISLEWKTRNQELEDNVHISPN--G 3073
Query: 226 TIISQYKLFPTRFARGRRITCVVKHPALEKDIRYSFI-LDIQYAPEVSVTGYDGNWFVGR 284
+II+ + TR + CV + + S + L + P VSV W
Sbjct: 3074 SIIT---IVGTRPSNHGTYRCVASN---AYGVAQSVVNLSVHGPPTVSVLPEGPVWVKVG 3127
Query: 285 KGVNLKCNADANPPPFKSVWSRLDG------QWPDGLLASDNTLHFVHPLTFNYSGVYIC 338
K V L+C A P + W+R+ Q GL+ S L + + +G Y+C
Sbjct: 3128 KAVTLEC-VSAGEPRSSARWTRISSTPAKLEQRTYGLMDSHAVLQ-ISSAKPSDAGTYVC 3185
Query: 339 KVTNSLGQRSDQKVIYISDPPTTTTLQPTIQWHPSTADIE 378
N+LG + ++V I D P +Q + +E
Sbjct: 3186 LAQNALG-TAQKQVEVIVDTGAMAPGAPQVQAEEAELTVE 3224
Score = 52.8 bits (125), Expect = 8e-07
Identities = 71/303 (23%), Positives = 106/303 (34%), Gaps = 50/303 (16%)
Query: 69 VW---GKNVSLKCLIEVNETITQISWEKIHGKSSQTVAVHHPQYGFSVQGEYQGRVLFKN 125
VW GK V+L+C + E + W +I SS + YG
Sbjct: 3122 VWVKVGKAVTLEC-VSAGEPRSSARWTRI---SSTPAKLEQRTYGLMD------------ 3165
Query: 126 YSLNDATITLHNIGFSDSGKYICKAVTFPLGNAQSSTTVTV---LVEPTVSLIKGPDSLI 182
+ A + + + SD+G Y+C A LG AQ V V + P ++ ++ +
Sbjct: 3166 ---SHAVLQISSAKPSDAGTYVCLAQN-ALGTAQKQVEVIVDTGAMAPGAPQVQAEEAEL 3221
Query: 183 DGGNETVAAICIAATGKPVAHIDWEGDLG------EMESTTTSFPNETATIISQYKLFPT 236
A + +ATG P I W +E T P QY
Sbjct: 3222 TVEAGHTATLRCSATGSPAPTIHWSKLRSPLPWQHRLEGDTLIIPRVAQQDSGQY----- 3276
Query: 237 RFARGRRITCVVKHPALEKDIRYSFILDIQYAPEVSVTGYDGNWFVGRKGVNLKCNADAN 296
C PA + + IL ++ P + + G V L+C A
Sbjct: 3277 --------ICNATSPAGHAEA--TIILHVESPPYATTVPEHASVQAGET-VQLQCLAHGT 3325
Query: 297 PPPFKSVWSRLDGQWPDGLLASDNTLHFVHPLTFNYSGVYICKVTNSLGQRSDQKVIYIS 356
PP WSR+ P A + LHF + SG Y C+VTN +G + +
Sbjct: 3326 PP-LTFQWSRVGSSLPGRATARNELLHFERAAPED-SGRYRCRVTNKVGSAEAFAQLLVQ 3383
Query: 357 DPP 359
PP
Sbjct: 3384 GPP 3386
Score = 51.6 bits (122), Expect = 2e-06
Identities = 73/319 (22%), Positives = 121/319 (37%), Gaps = 43/319 (13%)
Query: 56 LAGPIIV--EPHVTAVWGKNVSLKCLIEVNETITQISWEKIHGKSSQTVAVHHPQYGFSV 113
L P+I P T G++ S KCLI + W+ + + V +
Sbjct: 3019 LRSPVISIDPPSSTVQQGQDASFKCLIHDGAAPISLEWKTRNQELEDNVHI--------- 3069
Query: 114 QGEYQGRVLFKNYSLNDATITLHNIGFSDSGKYICKAVTFPLGNAQSSTTVTVLVEPTVS 173
S N + IT+ S+ G Y C A G AQS ++V PTVS
Sbjct: 3070 -------------SPNGSIITIVGTRPSNHGTYRCVASN-AYGVAQSVVNLSVHGPPTVS 3115
Query: 174 LI-KGPDSLIDGGNETVAAICIAATGKPVAHIDWEGDLGEMESTTTSFPNETATIISQYK 232
++ +GP + G + V C++A G+P + W + ST T ++ +
Sbjct: 3116 VLPEGPVWVKVG--KAVTLECVSA-GEPRSSARWT----RISSTPAKLEQRTYGLMDSHA 3168
Query: 233 LFPTRFAR---GRRITCVVKHPALEKDIRYSFILDIQY----APEVSVTGYDGNWFVGRK 285
+ A+ C+ ++ + I+D AP+V + G
Sbjct: 3169 VLQISSAKPSDAGTYVCLAQNALGTAQKQVEVIVDTGAMAPGAPQVQAEEAELTVEAGHT 3228
Query: 286 GVNLKCNADANPPPFKSVWSRLDGQWPDGLLASDNTLHFVHPLTFNYSGVYICKVTNSLG 345
L+C+A +P P WS+L P +TL + + SG YIC T+ G
Sbjct: 3229 AT-LRCSATGSPAPTIH-WSKLRSPLPWQHRLEGDTL-IIPRVAQQDSGQYICNATSPAG 3285
Query: 346 QRSDQKVIYISDPPTTTTL 364
++++ PP TT+
Sbjct: 3286 HAEATIILHVESPPYATTV 3304
Score = 49.3 bits (116), Expect = 9e-06
Identities = 74/316 (23%), Positives = 127/316 (40%), Gaps = 41/316 (12%)
Query: 118 QGRVLFKNYSLNDATITLHNIGFSDSGKYICKAVTFPLGNAQSSTTVTVLVEPTV--SLI 175
+G L +S+ D + + N+ S G YIC+A P G AQ+S + + P+V ++
Sbjct: 3436 EGGQLPPGHSVQDGVLRIQNLDQSCQGTYICQA-HGPWGKAQASAQLVIQALPSVLINIR 3494
Query: 176 KGPDSLIDGGNETVAAICIAATGKPVAHIDWEGDLGEMESTTTSFPNETATIISQYKLFP 235
+++ G V C+ A G P + W G + ++ ++ ++
Sbjct: 3495 TSVQTVVVG--HAVEFECL-ALGDPKPQVTWSKVGGHLRPGIV----QSGGVV---RIAH 3544
Query: 236 TRFARGRRITCVVKHPALEKDIRYSFILDIQYAPEVSVTGYDGNWFVGRKGVNLKCNADA 295
A + C + A + +L +Q P++S+ + G V C A
Sbjct: 3545 VELADAGQYRCTATNAA--GTTQSHVLLLVQALPQISMP-QEVRVPAGSAAV-FPCIASG 3600
Query: 296 NPPPFKSVWSRLDGQWPDGLLASDNTLHFVHPLTFNYSGVYICKVTNSLG--------QR 347
P P S WS+LDG P +N L + + +G Y+C TN G Q
Sbjct: 3601 YPTPDIS-WSKLDGSLPPDSRLENNML-MLPSVRPQDAGTYVCTATNRQGKVKAFAHLQV 3658
Query: 348 SDQKVIYISDPPTTTTLQPTIQ-----------WHPSTADIEDLATEPKKLPFPLSTLAT 396
++ V Y + P + PTI+ + P +AD L K++P + LA
Sbjct: 3659 PERVVPYFTQTPYSFLPLPTIKDAYRKFEIKITFRPDSADGMLLYNGQKRVPGSPTNLAN 3718
Query: 397 IKDDTIATIIASVVGG 412
+ D I+ +VGG
Sbjct: 3719 RQPDFIS---FGLVGG 3731
Score = 38.1 bits (87), Expect = 0.021
Identities = 52/226 (23%), Positives = 82/226 (36%), Gaps = 31/226 (13%)
Query: 133 ITLHNIGFSDSGKYICKAVTFPLGNAQSSTTVTVLVEPTVSL----IKGPDSLIDGGNET 188
+T+ N+ SD+G Y+C Q + T+ V T+S I P + G
Sbjct: 1825 LTIRNVQLSDAGTYVCTGSNM-FAMDQGTATLHVQASGTLSAPVVSIHPPQLTVQPGQ-- 1881
Query: 189 VAAICIAATGKPVAHIDWEGDLG-------EMESTTTSFPNETATIISQYKLFPTRFARG 241
+A +ATG P ++W G G ++ P T +QY L + G
Sbjct: 1882 LAEFRCSATGSPTPTLEWTGGPGGQLPAKAQIHGGILRLPAVEPTDQAQY-LCRAHSSAG 1940
Query: 242 RRITCVVKHPALEKDIRYSFILDIQYAPEVSVTGYDGNWFVGRKGVNLKCNADANPPPFK 301
+++ V H + P V V+ GR V L C A A P
Sbjct: 1941 QQVARAVLH------------VHGGGGPRVQVSPERTQVHAGRT-VRLYCRA-AGVPSAT 1986
Query: 302 SVWSRLDGQWPDGLLA--SDNTLHFVHPLTFNYSGVYICKVTNSLG 345
W + G P + +D + +T +G Y+C T+ G
Sbjct: 1987 ITWRKEGGSLPPQARSERTDIATLLIPAITTADAGFYLCVATSPAG 2032
Score = 37.7 bits (86), Expect = 0.027
Identities = 69/319 (21%), Positives = 122/319 (38%), Gaps = 65/319 (20%)
Query: 59 PIIVEPHVTAVW-GKNVSLKCLIEVNETITQISWEKIHGKSSQTVAVHHPQYGFSVQGEY 117
PI +EP + V G+ + L C++ ++ Q++W K G ++ V H +G
Sbjct: 2342 PIRIEPSSSQVAEGQTLDLNCVVP-GQSHAQVTWHKRGG----SLPVRHQTHG------- 2389
Query: 118 QGRVLFKNYSLNDATITLHNIGFSDSGKYICKAV--TFPLGNAQSSTTVTVL-------- 167
+ + L+ +DSG+Y+C+ + + PL ++S VT+
Sbjct: 2390 -------------SLLRLYQASPADSGEYVCRVLGSSVPL---EASVLVTIEPAGSVPAL 2433
Query: 168 -VEPTVSLIKGPDSLIDGGNETVAAICIAATGKPVAHIDWEGDLGEMESTTTSFPNETAT 226
V PTV + + +G +T+ C+ A G+ A + W G S P
Sbjct: 2434 GVTPTVRIESSSSQVAEG--QTLDLNCLVA-GQAHAQVTWHKRGG-------SLPARHQV 2483
Query: 227 IISQYKLFPTRFARGRRITCVVKHPALEKDIRYSFILDIQ----------YAPEVSVTGY 276
S+ +L A C V + ++ S ++ IQ A V +
Sbjct: 2484 HGSRLRLLQVTPADSGEYVCRVVGSSGTQEA--SVLVTIQQRLSGSHSQGVAYPVRIESS 2541
Query: 277 DGNWFVGRKGVNLKCNADANPPPFKSVWSRLDGQWPDGLLASDNTLHFVHPLTFNYSGVY 336
+ G ++L C A+ P W + G P + L + +T SG Y
Sbjct: 2542 SASLANGHT-LDLNCLV-ASQAPHTITWYKRGGSLPSRHQIVGSRLR-IPQVTPADSGEY 2598
Query: 337 ICKVTNSLGQRSDQKVIYI 355
+C V+N G R ++ I
Sbjct: 2599 VCHVSNGAGSRETSLIVTI 2617
Score = 35.4 bits (80), Expect = 0.14
Identities = 38/157 (24%), Positives = 63/157 (40%), Gaps = 40/157 (25%)
Query: 59 PIIVEPHVTAVW-GKNVSLKCLIEVNETITQISWEKIHGKSSQTVAVHHPQYGFSVQGEY 117
PI +EP + V G+ + L C++ + Q++W K G ++ H +G
Sbjct: 2153 PIRIEPSSSHVAEGQTLDLNCVVP-GQAHAQVTWHKRGG----SLPARHQTHG------- 2200
Query: 118 QGRVLFKNYSLNDATITLHNIGFSDSGKYICKAVTFPLGNAQSSTTVTVLVEPTVSLIKG 177
+ + LH + +DSG+Y+C V +VLV S+I G
Sbjct: 2201 -------------SLLRLHQVTPADSGEYVCHVV-----GTSGPLEASVLVTIEASVIPG 2242
Query: 178 --PDSLIDGGNETVA------AICIAATGKPVAHIDW 206
P I+ + TVA C+ A G+ A + W
Sbjct: 2243 PIPPVRIESSSSTVAEGQTLDLSCVVA-GQAHAQVTW 2278
Score = 33.5 bits (75), Expect = 0.52
Identities = 64/304 (21%), Positives = 112/304 (36%), Gaps = 58/304 (19%)
Query: 71 GKNVSLKCLIEVNETITQISWEKIHGKSSQTVAVHHPQYGFSVQGEYQGRVLFKNYSLND 130
G+ + L CL+ + Q++W K +G L + ++
Sbjct: 2451 GQTLDLNCLV-AGQAHAQVTWHK------------------------RGGSLPARHQVHG 2485
Query: 131 ATITLHNIGFSDSGKYICKAVTFPLGNAQSSTTVTVL----------VEPTVSLIKGPDS 180
+ + L + +DSG+Y+C+ V G ++S VT+ V V + S
Sbjct: 2486 SRLRLLQVTPADSGEYVCRVVG-SSGTQEASVLVTIQQRLSGSHSQGVAYPVRIESSSAS 2544
Query: 181 LIDGGNETVAAICIAATGKPVAHIDWEGDLGEMESTTTSFPNETATIISQYKLFPTRFAR 240
L +G T+ C+ A+ P I W G S P+ + S+ ++ A
Sbjct: 2545 LANG--HTLDLNCLVASQAPHT-ITWYKRGG-------SLPSRHQIVGSRLRIPQVTPAD 2594
Query: 241 GRRITCVVKHPALEKDIRYSFILDIQ-----YAPEVSV---TGYDGNWFVGRKGVNLKCN 292
C V + A ++ S I+ IQ + P VS V + ++L C
Sbjct: 2595 SGEYVCHVSNGAGSRET--SLIVTIQGSGSSHVPSVSPPIRIESSSPTVVEGQTLDLNC- 2651
Query: 293 ADANPPPFKSVWSRLDGQWPDGLLASDNTLHFVHPLTFNYSGVYICKVTNSLGQRSDQKV 352
A P W + G P + L +H ++ SG Y+C+ N++ V
Sbjct: 2652 VVARQPQAIITWYKRGGSLPSRHQTHGSHLR-LHQMSVADSGEYVCRANNNIDALEASIV 2710
Query: 353 IYIS 356
I +S
Sbjct: 2711 ISVS 2714
Score = 30.8 bits (68), Expect = 3.4
Identities = 21/93 (22%), Positives = 39/93 (41%), Gaps = 4/93 (4%)
Query: 287 VNLKCNADANPPPFKSVWSRL-DGQWPDGLLASDNTLHFVHPLTFNYSGVYICKVTNSLG 345
V C A + P + VW+RL +G+ P + N + + + + +G Y+C +N
Sbjct: 1789 VTFICTAKSKSPAYTLVWTRLHNGKLPTRAM-DFNGILTIRNVQLSDAGTYVCTGSNMFA 1847
Query: 346 QRSDQKVIYISDPPTTTTLQPTIQWHPSTADIE 378
DQ + + T P + HP ++
Sbjct: 1848 M--DQGTATLHVQASGTLSAPVVSIHPPQLTVQ 1878
Score = 30.0 bits (66), Expect = 5.7
Identities = 22/96 (22%), Positives = 42/96 (43%), Gaps = 26/96 (27%)
Query: 71 GKNVSLKCLIEVNETITQISWEKIHGKSSQTVAVHHPQYGFSVQGEYQGRVLFKNYSLND 130
G+ + L C++ + Q++W K G ++ HH G
Sbjct: 2741 GETLDLNCVVP-GQAHAQVTWHKRGG----SLPSHHQTRG-------------------- 2775
Query: 131 ATITLHNIGFSDSGKYICKAVTFPLGNAQSSTTVTV 166
+ + LH++ +DSG+Y+C+ V G ++S VT+
Sbjct: 2776 SRLRLHHVSPADSGEYVCR-VMGSSGPLEASVLVTI 2810
>gi|171460997 CD226 molecule precursor [Homo sapiens]
Length = 336
Score = 62.4 bits (150), Expect = 1e-09
Identities = 46/173 (26%), Positives = 75/173 (43%), Gaps = 12/173 (6%)
Query: 37 PPLLLLLFPLLLFSRLCGALAGPIIVEPHVTAVWGKNVSLKCLIEVNETITQISWEKIHG 96
P LLL L L ++ LC + H + + +N+SL+C+ +TQ+ W KI G
Sbjct: 4 PTLLLAL--LHVYRALCEEVLW------HTSVPFAENMSLECVYPSMGILTQVEWFKI-G 54
Query: 97 KSSQTVAVHHPQYGFSVQGEYQGRVLFKNYSL--NDATITLHNIGFSDSGKYICKAVTFP 154
++A+ P +G ++ Y RV F N ++ N+ T+ N D G Y C T+P
Sbjct: 55 TQQDSIAIFSPTHGMVIRKPYAERVYFLNSTMASNNMTLFFRNASEDDVGYYSCSLYTYP 114
Query: 155 LGNAQSSTTVTVLVEPTVSLIKGPDSLIDGGNETVAAICIAATGKPVAHIDWE 207
G Q V V + + + ++ + V C PV + WE
Sbjct: 115 QGTWQKVIQV-VQSDSFEAAVPSNSHIVSEPGKNVTLTCQPQMTWPVQAVRWE 166
Score = 36.6 bits (83), Expect = 0.061
Identities = 19/84 (22%), Positives = 40/84 (47%)
Query: 65 HVTAVWGKNVSLKCLIEVNETITQISWEKIHGKSSQTVAVHHPQYGFSVQGEYQGRVLFK 124
H+ + GKNV+L C ++ + + WEKI + + + +G + ++ +++
Sbjct: 139 HIVSEPGKNVTLTCQPQMTWPVQAVRWEKIQPRQIDLLTYCNLVHGRNFTSKFPRQIVSN 198
Query: 125 NYSLNDATITLHNIGFSDSGKYIC 148
+ I + ++ SDSG Y C
Sbjct: 199 CSHGRWSVIVIPDVTVSDSGLYRC 222
>gi|118572606 hemicentin 1 [Homo sapiens]
Length = 5635
Score = 58.2 bits (139), Expect = 2e-08
Identities = 72/301 (23%), Positives = 123/301 (40%), Gaps = 38/301 (12%)
Query: 107 PQYGFSVQGEYQGRVLFKNYSLNDATITLHNIGFSDSGKYICKAVTFPLGNAQSSTTVTV 166
P +S +GE K + D ++ + + G +SG+Y+C A T G A+ +TV
Sbjct: 1010 PSVIWSKKGELISTSSAKFSAGADGSLYVVSPGGEESGEYVCTA-TNTAGYAKRKVQLTV 1068
Query: 167 LVEPTV-------SLIKGPDSLIDGGNETVAAICIAATGKPVAHIDWEGDLGEMESTTTS 219
V P V S K + + G E + + P+ I W E + +
Sbjct: 1069 YVRPRVFGDQRGLSQDKPVEISVLAGEEVTLPCEVKSLPPPI--ITWAK---ETQLISPF 1123
Query: 220 FPNETATIISQYKLFPTRFARGRRITCVVKHPALEKDIRYSFILDIQYAPEVSVTGYDGN 279
P T K+ TR + CV + A ++ + L++ P++
Sbjct: 1124 SPRHTFLPSGSMKITETRTSDSGMYLCVATNIA--GNVTQAVKLNVHVPPKIQRGPKHLK 1181
Query: 280 WFVGRKGVNLKCNADANPPPFKSVWSR------LDGQW----PDGLLASDNTLHFVHPLT 329
VG++ V++ CNA P P + WS+ +DG+ PDG L+ D T
Sbjct: 1182 VQVGQR-VDIPCNAQGTPLPVIT-WSKGGSTMLVDGEHHVSNPDGTLSIDQA-------T 1232
Query: 330 FNYSGVYICKVTNSLGQRSDQKVIYISDPPTTTTLQPTIQWHPSTADIEDLATEPKKLPF 389
+ +G+Y C TN G + +++ +PPT L+P +T E +A + + P
Sbjct: 1233 PSDAGIYTCVATNIAGTDETEITLHVQEPPTVEDLEPPY----NTTFQERVANQRIEFPC 1288
Query: 390 P 390
P
Sbjct: 1289 P 1289
Score = 57.0 bits (136), Expect = 4e-08
Identities = 76/299 (25%), Positives = 116/299 (38%), Gaps = 49/299 (16%)
Query: 71 GKNVSLKCLIEVNETITQISWEKIHGKSSQTVAVHHPQYGFSVQGEYQGRVLFKNYSLND 130
G NV+L C ++ T I W ++ P FSV Q L
Sbjct: 807 GSNVTLPCYVQGYPEPT-IKWRRLDNMP----IFSRP---FSVSSISQ---------LRT 849
Query: 131 ATITLHNIGFSDSGKYICKAVTFPLGNAQSSTTVT--VLVEPTVSLIKGPDSLIDGGNET 188
+ + N+ SD G YIC+A G QS TTVT LV P + + ++I+G T
Sbjct: 850 GALFILNLWASDKGTYICEAEN-QFGKIQSETTVTVTGLVAPLIGISPSVANVIEGQQLT 908
Query: 189 VAAICIAATGKPVAHIDWEGDLGEMESTTTSFPNETATIISQYKLFPTR--FARGRRITC 246
+ C G P+ W ++++ N T+ S L R G TC
Sbjct: 909 LP--CTLLAGNPIPERRW------IKNSAMLLQNPYITVRSDGSLHIERVQLQDGGEYTC 960
Query: 247 VVKHPALEKDIRYSFIL----DIQYAPEVSVTGYDGNWFVGRKGVNLKCNADANPPPFKS 302
V + A + S ++ IQ+ ++ T + V L C A NP P
Sbjct: 961 VASNVAGTNNKTTSVVVHVLPTIQHGQQILST-------IEGIPVTLPCKASGNPKP-SV 1012
Query: 303 VWSR----LDGQWPDGLLASDNTLHFVHPLTFNYSGVYICKVTNSLG--QRSDQKVIYI 355
+WS+ + +D +L+ V P SG Y+C TN+ G +R Q +Y+
Sbjct: 1013 IWSKKGELISTSSAKFSAGADGSLYVVSP-GGEESGEYVCTATNTAGYAKRKVQLTVYV 1070
Score = 46.6 bits (109), Expect = 6e-05
Identities = 59/235 (25%), Positives = 91/235 (38%), Gaps = 36/235 (15%)
Query: 142 DSGKYICKAVTFPLGNAQSSTTVTVLVEPTVSLIKGPDSLIDGGNETVAAICIA------ 195
D G+YIC A T G + V VLV P I+GG+ET I +
Sbjct: 1706 DRGQYICVA-TSVAGEKEIKYEVDVLVPPA----------IEGGDETSYFIVMVNNLLEL 1754
Query: 196 ---ATGKPVAHIDW--EGDLGEMESTTTSFPNETATIISQYKLFPTRFARGRRITCVVKH 250
TG P I W +G L + N +I+Q ++ T R C+ +
Sbjct: 1755 DCHVTGSPPPTIMWLKDGQLIDERDGFKILLNGRKLVIAQAQVSNTGLYR-----CMAAN 1809
Query: 251 PALEKDIRYSFILDIQYAPEVSVTGYDGNWFVGRKGVNLKCNADANPPPFKSVWSRLD-- 308
A D + F + + P + +G V K V L+C A+ P P W + D
Sbjct: 1810 TA--GDHKKEFEVTVHVPPTIKSSGLSERVVVKYKPVALQCIANGIPNP-SITWLKDDQP 1866
Query: 309 ---GQWPDGLLASDNTLHFVHPLTFNYSGVYICKVTNSLGQRSDQKVIYISDPPT 360
Q + +S L L + +G Y C TN+ G+ +++ +PP+
Sbjct: 1867 VNTAQGNLKIQSSGRVLQIAKTLLED-AGRYTCVATNAAGETQQHIQLHVHEPPS 1920
Score = 46.6 bits (109), Expect = 6e-05
Identities = 61/235 (25%), Positives = 89/235 (37%), Gaps = 33/235 (14%)
Query: 141 SDSGKYICKAVTFPLGNAQSSTTVTVLVEPTVSLIKGPDSLIDGGNETVAAICIAATGKP 200
SDSG Y C A G AQ +++ V P+V+ + P + E V +C A G P
Sbjct: 3217 SDSGNYTCIASNME-GKAQKYYFLSIQVPPSVAGAEIPSDVSVLLGENVELVC-NANGIP 3274
Query: 201 VAHIDWEGD-----LGEMESTTTSFPNETATIISQYKLFPTRFARGRRITCVVKHPALEK 255
I W D GE E S T I ++ TCV +PA E+
Sbjct: 3275 TPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKY------TCVATNPAGEE 3328
Query: 256 DIRYSFILDIQYAPEVSVTGYDGNWFVGRK-------GVNLKCNADANPPPFKSVWSRLD 308
D F L++ P + GN K +N++C A PPP + W +
Sbjct: 3329 D--RIFNLNVYVTPTIR-----GNKDEAEKLMTLVDTSINIECRATGTPPP-QINWLKNG 3380
Query: 309 GQWPDG----LLASDNTLHFVHPLTFNYSGVYICKVTNSLGQRSDQKVIYISDPP 359
P LLA+ + V + + VY C +N G + + + PP
Sbjct: 3381 LPLPLSSHIRLLAAGQVIRIVRAQVSDVA-VYTCVASNRAGVDNKHYNLQVFAPP 3434
Score = 45.8 bits (107), Expect = 1e-04
Identities = 66/286 (23%), Positives = 109/286 (38%), Gaps = 36/286 (12%)
Query: 133 ITLHNIGFSDSGKYICKAVTFPLGNAQSSTTVTVLVEPT-VSLIKGPDSLIDGGNETVAA 191
+ L NI SD+G+Y+C AV G ++V P+ + + P+++ +V+
Sbjct: 2348 LQLKNIHVSDTGRYVCVAVNV-AGMTDKKYDLSVHAPPSIIGNHRSPENISVVEKNSVSL 2406
Query: 192 ICIAATGKPVAHIDWEGDLGEMESTTTSFPNETATIIS--QYKLFPTRFARGRRITCVVK 249
C A+G P+ I W D S N + +L T + TCVV+
Sbjct: 2407 TC-EASGIPLPSITWFKD-----GWPVSLSNSVRILSGGRMLRLMQTTMEDAGQYTCVVR 2460
Query: 250 HPALEKDIRYSFILDIQYAPE-VSVTGYDGNWFVGRKGVNLKCNADANPPPFKSVWSRLD 308
+ A E+ R F L + P V + ++ V L C NP P + W + D
Sbjct: 2461 NAAGEE--RKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVP-EITWHK-D 2516
Query: 309 GQWPDGLLASDNTLHFVHPLTF--------NYSGVYICKVTNSLGQRSDQKVIYISDPPT 360
GQ L D H + F ++G Y C ++ G +S + + PT
Sbjct: 2517 GQ----PLQEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVFVSPT 2572
Query: 361 TTTLQPTIQWHPSTADIEDLATEPKKL-----PFPLSTLATIKDDT 401
+ + D+ + P L +P +T+ KD T
Sbjct: 2573 IA----GVGSDGNPEDVTVILNSPTSLVCEAYSYPPATITWFKDGT 2614
Score = 44.7 bits (104), Expect = 2e-04
Identities = 75/326 (23%), Positives = 125/326 (38%), Gaps = 48/326 (14%)
Query: 128 LNDATITLHNIGFSDSGKYICKAVTFPLGNAQSSTTVTVLVEPTVSLIKGPDSLIDGGNE 187
L+ ++ + + D+G Y C A G++ +ST +TV V P + +G ++ NE
Sbjct: 4128 LSSGSLQIAFVQPGDAGHYTCMAANVA-GSSSTSTKLTVHVPPRIRSTEGHYTV----NE 4182
Query: 188 TVAAI--CIAATGKPVAHIDWEGDLGEMESTTTSFPNET--ATIISQYKLFPTRFARGRR 243
AI C+A G P I+W+ D + + + E I+ L + F
Sbjct: 4183 NSQAILPCVA-DGIPTPAINWKKDNVLLANLLGKYTAEPYGELILENVVLEDSGF----- 4236
Query: 244 ITCVVKHPALEKDIRYSFILDIQYAPEVSVTGYDGNWFVGRKGVNLKCNADANPPPFKSV 303
TCV + A E ++ L + P + D + G + + L C A P P K
Sbjct: 4237 YTCVANNAAGEDT--HTVSLTVHVLPTFTELPGDVSLNKGEQ-LRLSCKATGIPLP-KLT 4292
Query: 304 WSRLDGQWPDGLLASDNTLHFV-HPLTFNYSGVYICKVTNSLGQRSDQKVIYISDPP--- 359
W+ + P + + V ++ SG Y+C NS+G +Y+ +PP
Sbjct: 4293 WTFNNNIIPAHFDSVNGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPPVFK 4352
Query: 360 --------------------TTTTLQPTIQWHPSTADIEDLATEPKKLPFPLSTLATIKD 399
PTIQW+ DIE + L+ T+ +
Sbjct: 4353 GDYPSNWIEPLGGNAILNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGNGSLAIYGTVNE 4412
Query: 400 DT-----IATIIASVVGGALFIVLVS 420
D +AT A VV ++ + L S
Sbjct: 4413 DAGDYTCVATNEAGVVERSMSLTLQS 4438
Score = 43.5 bits (101), Expect = 5e-04
Identities = 54/216 (25%), Positives = 97/216 (44%), Gaps = 21/216 (9%)
Query: 141 SDSGKYICKAVTFPLGNAQSSTTVTVLVEPTVSLIKGPDS--LIDGGNETVAAICIAATG 198
SD+G+Y+C+A+ G + + V V P+ I+GP+ +++ + V C ATG
Sbjct: 3123 SDTGQYVCRAINV-AGRDDKNFHLNVYVPPS---IEGPEREVIVETISNPVTLTC-DATG 3177
Query: 199 KPVAHIDWEGDLGEMESTTTSFPNETATIISQYKLFPTRFARGRRITCVVKHPALEKDIR 258
P I W + +E+ + S + S+ ++ ++ + TC+ + +E +
Sbjct: 3178 IPPPTIAWLKNHKRIEN-SDSLEVRILSGGSKLQIARSQHSDSGNYTCIASN--MEGKAQ 3234
Query: 259 YSFILDIQYAPEVSVTGY--DGNWFVGRKGVNLKCNADANPPPFKSVWSRLDGQWPDG-- 314
+ L IQ P V+ D + +G + V L CNA+ P P W + G
Sbjct: 3235 KYYFLSIQVPPSVAGAEIPSDVSVLLG-ENVELVCNANGIPTPLIQ-WLKDGKPIASGET 3292
Query: 315 ----LLASDNTLHFVHPLTFNYSGVYICKVTNSLGQ 346
+ A+ +TL+ LT + +G Y C TN G+
Sbjct: 3293 ERIRVSANGSTLNIYGALTSD-TGKYTCVATNPAGE 3327
Score = 42.0 bits (97), Expect = 0.001
Identities = 53/226 (23%), Positives = 91/226 (40%), Gaps = 20/226 (8%)
Query: 142 DSGKYICKAVTFPLGNAQSSTTVTVLVEPTVSLIKGPDSLIDGGNETVAAICIAATGKPV 201
DSGKY C A G + VL P ++ + + + N + CIA+ G P
Sbjct: 3500 DSGKYTCIASN-EAGEVSKHFILKVLEPPHINGSEEHEEISVIVNNPLELTCIAS-GIPA 3557
Query: 202 AHIDWEGD---LGEMESTTTSFPNETATIISQYKLFPTRFARGRRITCVVKHPALEKDIR 258
+ W D L + + T E I + + R TC+ PA + D
Sbjct: 3558 PKMTWMKDGRPLPQTDQVQTLGGGEVLRIST------AQVEDTGRYTCLASSPAGDDDKE 3611
Query: 259 YSFILDIQYAPEVSVTGYDGNWFVGR-KGVNLKCNADANPPPFKSVWSRLDGQ----WPD 313
Y ++ + P ++ T + V R + V L+C +DA PPP W R +G+ P
Sbjct: 3612 Y--LVRVHVPPNIAGTDEPRDITVLRNRQVTLECKSDAVPPPV-ITWLR-NGERLQATPR 3667
Query: 314 GLLASDNTLHFVHPLTFNYSGVYICKVTNSLGQRSDQKVIYISDPP 359
+ S ++ + Y C +N G+ + + ++ ++ PP
Sbjct: 3668 VRILSGGRYLQINNADLGDTANYTCVASNIAGKTTREFILTVNVPP 3713
Score = 41.2 bits (95), Expect = 0.002
Identities = 67/272 (24%), Positives = 103/272 (37%), Gaps = 35/272 (12%)
Query: 133 ITLHNIGFSDSGKYICKAVTFPLGNAQSSTTVTVLVEPTVSLIKGPDSLIDGGNETVAAI 192
I + + SD+G Y C A+ G + ++ V V P++S G N VA +
Sbjct: 1976 IDIESAQISDAGIYKCVAIN-SAGATELFYSLQVHVAPSIS----------GSNNMVAVV 2024
Query: 193 C-------IAATGKPVAHIDWEGDLGEMESTTTSFPNETATIISQYKLFPT--RFARGRR 243
A G P + W D S +SF N + L T + + R
Sbjct: 2025 VNNPVRLECEARGIPAPSLTWLKD----GSPVSSFSNGLQVLSGGRILALTSAQISDTGR 2080
Query: 244 ITCVVKHPALEKDIRYSFILDIQYAPEVSVTGYDGNWFVG-RKGVNLKCNADANPPPFKS 302
TCV + A EK +D++ ++ G + N V + V L C +DA PPP
Sbjct: 2081 YTCVAVNAAGEKQRD----IDLRVYVPPNIMGEEQNVSVLISQAVELLCQSDAIPPP-TL 2135
Query: 303 VWSRLDGQ---WPDGLLASDN-TLHFVHPLTFNYSGVYICKVTNSLGQRSDQKVIYISDP 358
W + DG GL S+N ++ + +G Y C+ TN G+ + I P
Sbjct: 2136 TWLK-DGHPLLKKPGLSISENRSVLKIEDAQVQDTGRYTCEATNVAGKTEKNYNVNIWVP 2194
Query: 359 PTTTTLQPTIQWHPSTADIEDLATEPKKLPFP 390
P Q ++ L E +P P
Sbjct: 2195 PNIGGSDELTQLTVIEGNLISLLCESSGIPPP 2226
Score = 41.2 bits (95), Expect = 0.002
Identities = 56/239 (23%), Positives = 96/239 (40%), Gaps = 15/239 (6%)
Query: 127 SLNDATITLHNIGFSDSGKYICKAVTFPLGNAQSSTTVTVLVEPTVSLIKGPDSLIDGGN 186
S N +T+ ++ SD+GKY C A T P G + V V PT+ K +
Sbjct: 3298 SANGSTLNIYGALTSDTGKYTCVA-TNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTLV 3356
Query: 187 ETVAAICIAATGKPVAHIDWEGDLGEMESTTTSFPNETATIISQYKLFPTRFARGRRITC 246
+T I ATG P I+W + + ++ +I ++ + + TC
Sbjct: 3357 DTSINIECRATGTPPPQINWLKNGLPLPLSSHIRLLAAGQVI---RIVRAQVSDVAVYTC 3413
Query: 247 VVKHPALEKDIRYSFILDIQYAPEV-SVTGYDGNWFVGRKGVNLKCNADANPPPFKSVWS 305
V + A + Y+ L + P + + G + + ++ C D P P W
Sbjct: 3414 VASNRAGVDNKHYN--LQVFAPPNMDNSMGTEEITVLKGSSTSMACITDGTPAP-SMAWL 3470
Query: 306 RLDGQWPDGL-----LASDNTLHFVHPLTFNYSGVYICKVTNSLGQRSDQKVIYISDPP 359
R DGQ P GL +++ + + SG Y C +N G+ S ++ + +PP
Sbjct: 3471 R-DGQ-PLGLDAHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEPP 3527
Score = 40.8 bits (94), Expect = 0.003
Identities = 55/237 (23%), Positives = 89/237 (37%), Gaps = 17/237 (7%)
Query: 133 ITLHNIGFSDSGKYICKAVTFPLGNAQSSTTVTVLVEPTVSLIKGPDSLIDGGNETVAAI 192
+ L N+ DSG Y C A G + ++TV V PT + + G SL G E +
Sbjct: 4224 LILENVVLEDSGFYTCVANN-AAGEDTHTVSLTVHVLPTFTELPGDVSLNKG--EQLRLS 4280
Query: 193 CIAATGKPVAHIDWEGDLGEMESTTTSFPNETATIISQYKLFPTRFARGRRITCVVKHPA 252
C ATG P+ + W + + + S + +I + ++ G +
Sbjct: 4281 C-KATGIPLPKLTWTFNNNIIPAHFDSVNGHSELVIERV----SKEDSGTYVCTAENSVG 4335
Query: 253 LEKDIRYSFILDIQYAPEVSVTGYDGNWFVGRKG-VNLKCNADANPPPFKSVWSR--LDG 309
K I + ++ + P V Y NW G L C +P P W+R +D
Sbjct: 4336 FVKAIGFVYVKE----PPVFKGDYPSNWIEPLGGNAILNCEVKGDPTPTIQ-WNRKGVDI 4390
Query: 310 QWPDGLLASDNTLHFVHPLTFNYSGVYICKVTNSLGQRSDQKVIYISDPPTTTTLQP 366
+ + N ++ +G Y C TN G + + PP TL+P
Sbjct: 4391 EISHRIRQLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQSPP-IITLEP 4446
Score = 40.4 bits (93), Expect = 0.004
Identities = 71/342 (20%), Positives = 115/342 (33%), Gaps = 55/342 (16%)
Query: 66 VTAVWGKNVSLKCLIEVNETITQISWEKIHGKSSQTVAVHHPQYGFSVQGEYQGRVLFKN 125
++ + G+ V+L C ++ + I+W K +Q ++ P++ F G
Sbjct: 1089 ISVLAGEEVTLPCEVK-SLPPPIITW----AKETQLISPFSPRHTFLPSG---------- 1133
Query: 126 YSLNDATITLHNIGFSDSGKYICKAVTFPLGNAQSSTTVTVLVEPTVSLIKGPDSLIDGG 185
++ + SDSG Y+C A GN + + V V P + +GP L
Sbjct: 1134 ------SMKITETRTSDSGMYLCVATNIA-GNVTQAVKLNVHVPPKIQ--RGPKHLKVQV 1184
Query: 186 NETVAAICIAATGKPVAHIDWEGDLGEM----------ESTTTSFPNETATIISQYKLFP 235
+ V C A G P+ I W M T S T + Y
Sbjct: 1185 GQRVDIPC-NAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSIDQATPSDAGIYTCVA 1243
Query: 236 TRFARG--RRITCVVKHPALEKDIRYSFILDIQYAPEVSVTGYDGNWFVGRKGVNLKCNA 293
T A IT V+ P +D+ + Q V + + C A
Sbjct: 1244 TNIAGTDETEITLHVQEPPTVEDLEPPYNTTFQER-------------VANQRIEFPCPA 1290
Query: 294 DANPPPFKSVW----SRLDGQWPDGLLASDNTLHFVHPLTFNYSGVYICKVTNSLGQRSD 349
P P W L G+ P + D TL + +T +G YIC N G
Sbjct: 1291 KGTPKPTIK-WLHNGRELTGREPGISILEDGTLLVIASVTPYDNGEYICVAVNEAGTTER 1349
Query: 350 QKVIYISDPPTTTTLQPTIQWHPSTADIEDLATEPKKLPFPL 391
+ + + PP + + +L E + P P+
Sbjct: 1350 KYNLKVHVPPVIKDKEQVTNVSVLLNQLTNLFCEVEGTPSPI 1391
Score = 39.7 bits (91), Expect = 0.007
Identities = 63/275 (22%), Positives = 108/275 (39%), Gaps = 29/275 (10%)
Query: 129 NDATITLHNIGFSDSGKYICKAVTFPLGNAQSSTTVTVLVEPTVSLIKGPDSLIDGGNET 188
+D T+ + N D+G Y C A G + ++T+ + P + +++ + L+ G+ T
Sbjct: 662 SDGTLFIKNAAPKDAGIYGCLASN-SAGTDKQNSTLRYIEAPKLMVVQS-ELLVALGDIT 719
Query: 189 VAAICIAATGKPVAHIDW-EGDLGEMESTTTSFPNETATIISQYKLFPTRFARGRRITCV 247
V +G P + W +GDL ST ++ K+ T+ TCV
Sbjct: 720 VMEC--KTSGIPPPQVKWFKGDLELRPSTFLIID----PLLGLLKIQETQDLDAGDYTCV 773
Query: 248 VKHPALEKDIRYSFILDIQYAPEVSVTGYDGNWFVGRKGVNLKCNADANPPPFKSVWSRL 307
+ A + + LD+ P D + +G V L C P P W RL
Sbjct: 774 AINEAGRATGKIT--LDVGSPPVFIQEPADVSMEIG-SNVTLPCYVQGYPEPTIK-WRRL 829
Query: 308 DGQWPDGLLASDNTLH-------FVHPLTFNYSGVYICKVTNSLGQRSDQKVIYISDPPT 360
D S +++ F+ L + G YIC+ N G+ + + +
Sbjct: 830 DNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTV----- 884
Query: 361 TTTLQPTIQWHPSTADIEDLATEPKKLPFPLSTLA 395
T + P I PS A++ E ++L P + LA
Sbjct: 885 TGLVAPLIGISPSVANV----IEGQQLTLPCTLLA 915
Score = 39.3 bits (90), Expect = 0.009
Identities = 48/237 (20%), Positives = 100/237 (42%), Gaps = 13/237 (5%)
Query: 129 NDATITLHNIGFSDSGKYICKAVTFPLGNAQSSTTVTVLVEPTVSLIKGPDSLIDGGNET 188
N + + N +D G+Y+C A G+A+ + V V P+V K ++L N
Sbjct: 2924 NGRILQILNTQITDIGRYVCVAEN-TAGSAKKYFNLNVHVPPSVIGPKS-ENLTVVVNNF 2981
Query: 189 VAAICIAATGKPVAHIDWEGDLGEMESTTTSFPNETATIISQYKLFPTRFARGRRITCVV 248
++ C +G P + W + ++ T + + ++ + + G TC+
Sbjct: 2982 ISLTC-EVSGFPPPDLSWLKNEQPIKLNTNTLIVPGGRTL---QIIRAKVSDGGEYTCIA 3037
Query: 249 KHPALEKDIRYSFILDIQYAPEVSVTGYDGNWFVG-RKG--VNLKCNADANPPPFKSVW- 304
+ A E ++S L + P + + V R+G V+L+C ++A PPP + +
Sbjct: 3038 INQAGESKKKFS--LTVYVPPSIKDHDSESLSVVNVREGTSVSLECESNAVPPPVITWYK 3095
Query: 305 -SRLDGQWPDGLLASDNTLHFVHPLTFNYSGVYICKVTNSLGQRSDQKVIYISDPPT 360
R+ + + +D + + + +G Y+C+ N G+ + + PP+
Sbjct: 3096 NGRMITESTHVEILADGQMLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPS 3152
Score = 37.7 bits (86), Expect = 0.027
Identities = 38/149 (25%), Positives = 71/149 (47%), Gaps = 25/149 (16%)
Query: 59 PIIVEPH-VTAVWGKNVSLKCLIEVNETITQISWEKIHGKSSQTVAVHHPQYGFSVQGEY 117
P+I P+ VT G+ L CLI ++ ++W++ + + V + P
Sbjct: 521 PVIQVPNNVTVTPGERAVLTCLI-ISAVDYNLTWQR----NDRDVRLAEPA--------- 566
Query: 118 QGRVLFKNYSLNDATITLHNIGFSDSGKYICKAVTFPLGNAQSSTTVTVLVEPTVSLIKG 177
+ +L + ++ L ++ F+D+G+Y C V+ G++ +S +TV P V+++
Sbjct: 567 ------RIRTLANLSLELKSVKFNDAGEYHC-MVSSEGGSSAASVFLTVQEPPKVTVMPK 619
Query: 178 PDSLIDGGNETVAAICIAATGKPVAHIDW 206
S GG+E +I +ATG P I W
Sbjct: 620 NQS-FTGGSE--VSIMCSATGYPKPKIAW 645
Score = 37.7 bits (86), Expect = 0.027
Identities = 66/325 (20%), Positives = 120/325 (36%), Gaps = 52/325 (16%)
Query: 72 KNVSLKCLIEVNETITQISWEKIHGKSSQTVAVHHPQYGFSVQGEYQGRVLFKNYSLNDA 131
K+ L+C+ E T +I+W K +A +H +Y L +
Sbjct: 3728 KSTVLECIAEGVPT-PRITWRK----DGAVLAGNHARYSI----------------LENG 3766
Query: 132 TITLHNIGFSDSGKYICKAVTFPLGNAQSSTTVTVLVEPTVSLIKGPDSLIDGGNETVAA 191
+ + + +D+G+Y+C A T G + + V V P+++ GP ++ N
Sbjct: 3767 FLHIQSAHVTDTGRYLCMA-TNAAGTDRRRIDLQVHVPPSIA--PGPTNMTVIVNVQTTL 3823
Query: 192 ICIAATGKPVAHIDWE--GDLGEMESTTTSFP--NETATIISQYKLFPTRFARGRRITCV 247
C ATG P I+W G L ++ S+ + + +I + T C
Sbjct: 3824 AC-EATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTA-----TYECT 3877
Query: 248 VKHPALEKDIRYSFILDIQYAPEVSVTGYDGNWFVGRKGVNLKCNADANPPPFKSVWSRL 307
V + A D + + L +Q P ++ D F+ K A+ PF S+
Sbjct: 3878 VTNGA--GDDKRTVDLTVQVPPSIADEPTD---FLVTKHAPAVITCTASGVPFPSIHWTK 3932
Query: 308 DG----QWPDGLLASDNTLHFVHPLTFNYSGVYICKVTNSLGQRSDQKVIYISDPPTTTT 363
+G DG + + N++G Y C N+ G +++ +PP
Sbjct: 3933 NGIRLLPRGDGYRILSSGAIEILATQLNHAGRYTCVARNAAGSAHRHVTLHVHEPPVI-- 3990
Query: 364 LQPTIQWHPSTADIEDLATEPKKLP 388
P +++ + P LP
Sbjct: 3991 -------QPQPSELHVILNNPILLP 4008
Score = 37.0 bits (84), Expect = 0.047
Identities = 63/272 (23%), Positives = 100/272 (36%), Gaps = 14/272 (5%)
Query: 128 LNDATI-TLHNIGFSDSGKYICKAVTFPLGNAQSSTTVTVLVEPTVSLIKGPDSLIDGGN 186
L D T+ + ++ D+G+YIC AV G + + V V P + + ++ N
Sbjct: 1317 LEDGTLLVIASVTPYDNGEYICVAVN-EAGTTERKYNLKVHVPPVIKDKEQVTNVSVLLN 1375
Query: 187 ETVAAICIAATGKPVAHIDWEGDLGEMESTTTSFPNETATIISQYKLFPTRFARGRRITC 246
+ C G P I W D ++ ++T I+ KLF R +C
Sbjct: 1376 QLTNLFC-EVEGTPSPIIMWYKDNVQVTESSTIQTVNNGKIL---KLFRATPEDAGRYSC 1431
Query: 247 VVKHPALEKDIRYSFILDIQYAPEVSVTGYDGNWFVG-RKGVNLKCNADANPPP----FK 301
K + + F +D+ P + T + V + V L+C P P FK
Sbjct: 1432 --KAINIAGTSQKYFNIDVLVPPTIIGTNFPNEVSVVLNRDVALECQVKGTPFPDIHWFK 1489
Query: 302 SVWSRLDGQWPDGLLASDNTLHFVHPLTFNYSGVYICKVTNSLGQRSDQKVIYISDPPTT 361
G LL LH + N G Y C V+N+ G+++ + I PP+
Sbjct: 1490 DGKPLFLGDPNVELLDRGQVLHLKNARR-NDKGRYQCTVSNAAGKQAKDIKLTIYIPPSI 1548
Query: 362 TTLQPTIQWHPSTADIEDLATEPKKLPFPLST 393
T + L E + LP P T
Sbjct: 1549 KGGNVTTDISVLINSLIKLECETRGLPMPAIT 1580
Score = 32.3 bits (72), Expect = 1.2
Identities = 60/246 (24%), Positives = 89/246 (36%), Gaps = 37/246 (15%)
Query: 128 LNDATITLHNIGFSDSGKYICKAVTFPLGNAQSSTTVTVLVEPTVSLIKGPDSLIDGGNE 187
L+ I + + +G+Y C A G+A T+ V P + P L N
Sbjct: 3947 LSSGAIEILATQLNHAGRYTCVARN-AAGSAHRHVTLHVHEPPVIQ--PQPSELHVILNN 4003
Query: 188 TVAAICIAATGKPVAHIDWEGDLGEMESTTTSFPNETATIISQYKLFPTRFARGRRIT-- 245
+ C ATG P I W+ E + ++ L +R R T
Sbjct: 4004 PILLPC-EATGTPSPFITWQ-----KEGINVNTSGRNHAVLPSGGLQISRAVREDAGTYM 4057
Query: 246 CVVKHPALEKDIRYSFILDIQYAPEVS------VTGYDGNWFVGRKGVNLKCNADANPPP 299
CV ++PA L++Q P +S V D K + L C AD PPP
Sbjct: 4058 CVAQNPA--GTALGKIKLNVQVPPVISPHLKEYVIAVD-------KPITLSCEADGLPPP 4108
Query: 300 FKSVWSRLDGQ-----WPDGLLASDN-TLHFVHPLTFNYSGVYICKVTNSLGQRSDQKVI 353
W + DG+ +L+S + + FV P +G Y C N G S +
Sbjct: 4109 -DITWHK-DGRAIVESIRQRVLSSGSLQIAFVQP---GDAGHYTCMAANVAGSSSTSTKL 4163
Query: 354 YISDPP 359
+ PP
Sbjct: 4164 TVHVPP 4169
Score = 31.6 bits (70), Expect = 2.0
Identities = 49/248 (19%), Positives = 101/248 (40%), Gaps = 29/248 (11%)
Query: 127 SLNDATITLHNIGFSDSGKYICKAVTFPLGNAQSSTTVTVLVEPTVSLIKGPDSL----- 181
S N + + + + D+G+Y C+A T G + + V + V P + G D L
Sbjct: 2153 SENRSVLKIEDAQVQDTGRYTCEA-TNVAGKTEKNYNVNIWVPPNIG---GSDELTQLTV 2208
Query: 182 IDGGNETVAAICIAATGKPVAHIDWEGDLGEMESTTTSFPNETATIIS---QYKLFPTRF 238
I+G ++ +C ++G P ++ W+ + S + I+S Q ++
Sbjct: 2209 IEG--NLISLLC-ESSGIPPPNLIWK----KKGSPVLTDSMGRVRILSGGRQLQISIAEK 2261
Query: 239 ARGRRITCVVKHPALEKDIRYSFILDIQYAPEVSVTGYDGNWFVGRKG--VNLKCNADAN 296
+ +CV + A Y+ L + P ++ +G + +G ++L+C
Sbjct: 2262 SDAALYSCVASNVAGTAKKEYN--LQVYIRPTITNSGSHPTEIIVTRGKSISLECEVQGI 2319
Query: 297 PPPFKSVWSRLDGQ---WPDGL-LASDNTLHFVHPLTFNYSGVYICKVTNSLGQRSDQKV 352
PPP W + DG G+ + + + + + + +G Y+C N G +
Sbjct: 2320 PPP-TVTWMK-DGHPLIKAKGVEILDEGHILQLKNIHVSDTGRYVCVAVNVAGMTDKKYD 2377
Query: 353 IYISDPPT 360
+ + PP+
Sbjct: 2378 LSVHAPPS 2385
Score = 30.8 bits (68), Expect = 3.4
Identities = 61/315 (19%), Positives = 115/315 (36%), Gaps = 46/315 (14%)
Query: 69 VWGKNVSLKCL-IEVNETITQISWEKIHGKSSQTVAVHHPQYGFSVQGEYQGRVLFKNYS 127
+WG +S K + I+VN T+T + A+ + G+ N +
Sbjct: 2674 LWGPGLSPKEVKIKVNNTLTL---------ECEAYAIPSASLSWYKDGQPLKSDDHVNIA 2724
Query: 128 LNDATITLHNIGFSDSGKYICKAVTFPLGNAQSSTTVTVLVEPTVSLIKGPDSLIDGG-- 185
N T+ + SD+G+Y C A G + V + V P+ + +++D G
Sbjct: 2725 ANGHTLQIKEAQISDTGRYTCVASNI-AGEDELDFDVNIQVPPSFQKLWEIGNMLDTGRN 2783
Query: 186 --------NETVAAICIAATGKPVAHIDWEGDLGEMEST--TTSFPNETATIISQYKLFP 235
N ++ C P + W D + S+ P I + K+
Sbjct: 2784 GEAKDVIINNPISLYC-ETNAAPPPTLTWYKDGHPLTSSDKVLILPGGRVLQIPRAKV-- 2840
Query: 236 TRFARGRRITCVVKHPALEKDIRYSFILDIQYAPEVSVTGYDGN-----WFVGRKGVNLK 290
R TCV + A E ++Y D++ + G + + + K ++
Sbjct: 2841 ---EDAGRYTCVAVNEAGEDSLQY----DVRVLVPPIIKGANSDLPEEVTVLVNKSALIE 2893
Query: 291 CNADANPPPFKSVWSRLDGQ-----WPDGLLASDNTLHFVHPLTFNYSGVYICKVTNSLG 345
C + +P P ++ W + DGQ L++ L ++ + G Y+C N+ G
Sbjct: 2894 CLSSGSPAP-RNSWQK-DGQPLLEDDHHKFLSNGRILQILNTQITDI-GRYVCVAENTAG 2950
Query: 346 QRSDQKVIYISDPPT 360
+ + PP+
Sbjct: 2951 SAKKYFNLNVHVPPS 2965
>gi|20127422 Down syndrome cell adhesion molecule isoform CHD2-42
precursor [Homo sapiens]
Length = 2012
Score = 57.0 bits (136), Expect = 4e-08
Identities = 79/342 (23%), Positives = 134/342 (39%), Gaps = 53/342 (15%)
Query: 58 GPIIVEP--HVTAVWGKNVSLKCLIEVNETITQISWEKIHGKSSQTVAVHHPQYGFSVQG 115
GP + P ++TA+ G++ + C + + I W K +S + +H Q F
Sbjct: 503 GPASIRPMKNITAIAGRDTYIHCRV-IGYPYYSIKWYK----NSNLLPFNHRQVAFE--- 554
Query: 116 EYQGRVLFKNYSLNDATITLHNIGFS-DSGKYICKAVTFPLGNAQSSTTVTVLVEPTVSL 174
N+ T+ L ++ D G+Y C + P + S VTV V P +
Sbjct: 555 -------------NNGTLKLSDVQKEVDEGEYTCNVLVQPQLSTSQSVHVTVKVPPFIQP 601
Query: 175 IKGPDSLIDGGNETVAAICIAATGKPVAHIDWEGDLGEMESTTTSFPNETATIISQYKLF 234
+ P I + V C+ +G I W+ D G + + S ++
Sbjct: 602 FEFPRFSI---GQRVFIPCVVVSGDLPITITWQKD-GRPIPGSLGVTIDNIDFTSSLRIS 657
Query: 235 PTRFARGRRITCVVKHPALEKDIRYSFILDIQYAPEVSVTGYDGNWFVGRKGVNLKCNAD 294
TC+ ++ A + + L ++ P+ V D + G K V L C+A+
Sbjct: 658 NLSLMHNGNYTCIARNEAAA--VEHQSQLIVRVPPKFVVQPRDQDGIYG-KAVILNCSAE 714
Query: 295 ANPPPFKSVWSRLDGQ-----WPDGL-----LASDNTLHFVHPLTFNYSGVYICKVTNSL 344
P P VW G P L + S+ +L H + + SG Y+CKV+N +
Sbjct: 715 GYPVP-TIVWKFSKGAGVPQFQPIALNGRIQVLSNGSLLIKHVVEED-SGYYLCKVSNDV 772
Query: 345 GQRSDQKVIYISDPPTTTTLQPTIQWHPSTADIEDLATEPKK 386
G K +Y+ T + I +P+T LAT+ +K
Sbjct: 773 G-ADVSKSMYL-----TVKIPAMITSYPNTT----LATQGQK 804
>gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 3874
Score = 54.3 bits (129), Expect = 3e-07
Identities = 73/316 (23%), Positives = 111/316 (35%), Gaps = 42/316 (13%)
Query: 126 YSLNDATITLHNIGFSDSGKYICKAVTFPLGNAQSSTTVTVLVEPTVSL-IKGPDSLIDG 184
+ L+ ++ L + SD+G Y C A P G TV VLV PT+ G +L+
Sbjct: 2077 FYLDGGSLVLKGLRASDAGAYTCVAHN-PAGEDARLHTVNVLVPPTIKQGADGSGTLVSR 2135
Query: 185 GNETVAAICIAATGKPVAHIDWEGD-LGEMESTTTSFPNETATIISQYKLFPTRFARGRR 243
E V +C G P H+ W D L S T T+ ++ + A
Sbjct: 2136 PGELVTMVC-PVRGSPPIHVSWLKDGLPLPLSQRTLLHGSGHTL----RISKVQLADAGI 2190
Query: 244 ITCVVKHPALEKDIRYSFILDIQYAPEVSVTGYDGNWFVGRKG-VNLKCNADANPPPFKS 302
TCV PA D +F L +Q P + + + V R V L C A P P S
Sbjct: 2191 FTCVAASPAGVAD--RNFTLQVQVPPVLEPVEFQNDVVVVRGSLVELPCEARGVPLPLVS 2248
Query: 303 VWSRLDGQWPDGLLASDNTLHFVHPLTFNYSGVYICKVTNSLGQRSDQKVIYISDPP--- 359
W + DG+ + + SG Y C + G+ + + +PP
Sbjct: 2249 -WMK-DGEPLLSQSLEQGPSLQLEAVGAGDSGTYSCVAVSEAGEARRHFQLTVMEPPHIE 2306
Query: 360 ---------------------TTTTLQPTIQWHPSTADIEDLATEPKKLPFPLSTLATIK 398
T QP I WH + L + + + ++
Sbjct: 2307 DSGQPTELSLTPGAPMELLCDAQGTPQPNITWHKDGQALTRLENNSR-----ATRVLRVR 2361
Query: 399 DDTIATIIASVVGGAL 414
D + T +A GA+
Sbjct: 2362 DAGLYTCLAESPAGAI 2377
Score = 53.5 bits (127), Expect = 5e-07
Identities = 56/227 (24%), Positives = 98/227 (43%), Gaps = 17/227 (7%)
Query: 126 YSLNDATITLHNIGFSDSGKYICKAVTFPLGNAQSSTTVTVLVEPTVSLIKGPDSLIDGG 185
Y+ + L SD+G Y CKA +G A+ +T + V V PT+ G ++
Sbjct: 360 YTRGGRQLQLGRAQSSDAGVYTCKASN-AVGAAEKATRLDVYVPPTIEGAGGRPYVVKAV 418
Query: 186 NETVAAICIAATGKPVAHIDWEGD-LGEMESTTTSFPNETATIISQYKLFPTRFARGRRI 244
A+ A G P + W + L ES + + + + +L A
Sbjct: 419 AGRPVALECVARGHPSPTLSWHHEGLPVAESNESRLETDGSVL----RLESPGEASSGLY 474
Query: 245 TCVVKHPALEKDIRYSFILDIQYAPEVSVTGYDGN--WFVGRKGVNLKCNADANPPPFKS 302
+CV PA E ++YS +++Q P++ V G VG+ + L C A +P P +
Sbjct: 475 SCVASSPAGEAVLQYS--VEVQVPPQLLVAEGLGQVTTIVGQP-LELPCQASGSPVP--T 529
Query: 303 VWSRLDGQWPDGL----LASDNTLHFVHPLTFNYSGVYICKVTNSLG 345
+ +G+ + L +AS T + + ++SG++ C+ TN G
Sbjct: 530 IQWLQNGRPAEELAGVQVASQGTTLHIDHVELDHSGLFACQATNEAG 576
Score = 48.1 bits (113), Expect = 2e-05
Identities = 59/227 (25%), Positives = 87/227 (38%), Gaps = 17/227 (7%)
Query: 141 SDSGKYICKAVTFPLGNAQSSTTVTVLVEPTVSLIKGPDSLIDGGNETVAAICIAATGKP 200
SD G Y CK V+ G A + T+TV V PT K G+ V ++ G P
Sbjct: 1905 SDKGLYSCK-VSNVAGEAVRTFTLTVQVPPTFENPKTETVSQVAGSPLVLTCDVS--GVP 1961
Query: 201 VAHIDWEGDLGEMESTTTSFPNETATIISQYKLFPTRFARGRRITCVVKHPALEKDIRYS 260
+ W D +ES+ + +L P A+ TCV ++ E R
Sbjct: 1962 APTVTWLKDRMPVESSAVHGVVSRGGRLQLSRLQP---AQAGTYTCVAENTQAEA--RKD 2016
Query: 261 FILDIQYAPEVSVTGYDGNWFVGR-KGVNLKCNADANPPPFKSVWSRLDG------QWPD 313
F++ + AP + +G V + V L C AD PPP W + DG P
Sbjct: 2017 FVVAVLVAPRIRSSGVAREHHVLEGQEVRLDCEADGQPPP-DVAWLK-DGSPLGQDMGPH 2074
Query: 314 GLLASDNTLHFVHPLTFNYSGVYICKVTNSLGQRSDQKVIYISDPPT 360
D + L + +G Y C N G+ + + + PPT
Sbjct: 2075 LRFYLDGGSLVLKGLRASDAGAYTCVAHNPAGEDARLHTVNVLVPPT 2121
Score = 47.0 bits (110), Expect = 5e-05
Identities = 65/250 (26%), Positives = 98/250 (39%), Gaps = 37/250 (14%)
Query: 132 TITLHNIGFSDSGKYICKAVTFPLGNAQSSTTVTVLVEPTVSLIKGPDSLIDGGNETVAA 191
++ L +G DSG Y C AV+ G A+ +TV+ P + P L +
Sbjct: 2266 SLQLEAVGAGDSGTYSCVAVS-EAGEARRHFQLTVMEPPHIEDSGQPTELSLTPGAPMEL 2324
Query: 192 ICIAATGKPVAHIDWEGDLGEMESTTTSFPNETATIISQYKLFPTRFARGRRITCVVKHP 251
+C A G P +I W D ++ T N AT + R TC+ + P
Sbjct: 2325 LC-DAQGTPQPNITWHKD---GQALTRLENNSRATRV-------LRVRDAGLYTCLAESP 2373
Query: 252 ALEKDIRYSFILDIQYAPEVSVTGYDGNWFV---GRKGVNLKCNADANPPPFKSVWSRLD 308
A I SF + +Q P ++ G G FV + L+C+ +A P P K W R
Sbjct: 2374 A--GAIEKSFRVRVQAPP--NIVGPRGPRFVVGLAPGQLVLECSVEAEPAP-KITWHR-- 2426
Query: 309 GQWPDGLLASDNTLHFVHP----------LTFNYSGVYICKVTNSLGQRSDQKVIYISDP 358
DG++ ++ H P L+ SG Y C N+ G S + I
Sbjct: 2427 ----DGIVLQEDA-HTQFPERGRFLQLQALSTADSGDYSCTARNAAGSTSVAFRVEIHTV 2481
Query: 359 PTTTTLQPTI 368
PT + P +
Sbjct: 2482 PTIRSGPPAV 2491
Score = 46.2 bits (108), Expect = 8e-05
Identities = 58/252 (23%), Positives = 98/252 (38%), Gaps = 25/252 (9%)
Query: 142 DSGKYICKAVTFPLGNAQSSTTVTVLVEPTVSLIKGPDSLIDGGNETVAAICIAATGKPV 201
D+G Y C A + P G + S V V P + +GP ++ + C + +P
Sbjct: 2362 DAGLYTCLAES-PAGAIEKSFRVRVQAPPNIVGPRGPRFVVGLAPGQLVLEC-SVEAEPA 2419
Query: 202 AHIDWEGD-LGEMESTTTSFPNETATIISQYKLFPTRFARGRRITCVVKHPALEKDIRYS 260
I W D + E T FP + +L A +C ++ A + +
Sbjct: 2420 PKITWHRDGIVLQEDAHTQFPERGRFL----QLQALSTADSGDYSCTARNAAGSTSV--A 2473
Query: 261 FILDIQYAPEVSVTGYDGNWFVGRKGVNLKCNADANPPPFKSVWSR----LDGQWPDGLL 316
F ++I P + N V + + L C AD P P S W + LD + P +
Sbjct: 2474 FRVEIHTVPTIRSGPPAVNVSVNQTAL-LPCQADGVPAPLVS-WRKDRVPLDPRSPRFEI 2531
Query: 317 ASDNTLHFVHPLTFNYSGVYICKVTNSLGQRSDQKVIYISDPPTTTTLQPTIQWHPSTAD 376
+ +L + P+ +G Y+C +NS G + + + +PP PS ++
Sbjct: 2532 LPEGSLR-IQPVLAQDAGHYLCLASNSAGSDRQGRDLRVLEPPAIA---------PSPSN 2581
Query: 377 IEDLATEPKKLP 388
+ A P LP
Sbjct: 2582 LTLTAHTPALLP 2593
Score = 42.7 bits (99), Expect = 9e-04
Identities = 69/283 (24%), Positives = 110/283 (38%), Gaps = 44/283 (15%)
Query: 127 SLNDATITLHNIGFSDSGKYICKAVTFPLGNAQSSTTVTVLVEPTVSL---IKGPDSLID 183
S++ + + SD+G Y C A G+ + + V V P ++L + GP +
Sbjct: 744 SVDGRVLRIEQAQLSDAGSYRCVASNVA-GSTELRYGLRVNVPPRITLPPSLPGPVLV-- 800
Query: 184 GGNETVAAICIAATGKPVAHIDWEGDLGEMESTTTS----FPNETATIISQYKLFPTRFA 239
N V C ATG P + W D + T FP ++ R +
Sbjct: 801 --NTPVRLTC-NATGAPSPTLMWLKDGNPVSPAGTPGLQVFPGGRVLTLAS-----ARAS 852
Query: 240 RGRRITCVVKHPALEKDIRYSFILDIQYAPEVSVTGYDGNW-FVGRKGVNLKCNADANPP 298
R +CV E R +L + P S+ G + N V + V L+C + A PP
Sbjct: 853 DSGRYSCVAVSAVGED--RQDVVLQVHMPP--SILGEELNVSVVANESVALECQSHAMPP 908
Query: 299 PFKSVWSRLDGQ----WPDGLLASDNTLHFVHPLTFNYSGVYICKVTNSLGQRSDQKVIY 354
P S W DG+ P L++D L V +G Y C+ N G+ +
Sbjct: 909 PVLSWWK--DGRPLEPRPGVHLSADKALLQVDRADVWDAGHYTCEALNQAGRSEKHYNLN 966
Query: 355 ISDPPT-------TTTLQPTIQWHPSTADIEDLATEPKKLPFP 390
+ P T T++ + HP++ L+ E + +PFP
Sbjct: 967 VWVAPVFPLRESHTLTVR---EGHPTS-----LSCECRGVPFP 1001
Score = 36.6 bits (83), Expect = 0.061
Identities = 50/226 (22%), Positives = 92/226 (40%), Gaps = 27/226 (11%)
Query: 142 DSGKYICKAVTFPLGNAQSSTTVTVLVEPTVSLIKGPDSLID----GGNETVAAICIAAT 197
++G+Y CKA +G + VL P + + + L++ + TV+ C A
Sbjct: 1624 NAGRYSCKASN-EVGEDWLHYELLVLTPPVI--LGDTEELVEEVTVNASSTVSLQC-PAL 1679
Query: 198 GKPVAHIDWEGDLGEMESTTTSFPNETATIISQYKLFPTRFAR---GRRITCVVKHPALE 254
G PV I W +++ P+ ++ ++ A CV ++ A
Sbjct: 1680 GNPVPTISW------LQNGLPFSPSPRLQVLEDGQVLQVSTAEVADAASYMCVAENQAGS 1733
Query: 255 KDIRYSFILDIQYAPEVSVTGYDGNWFVGRKGVNLKCNADANPPPFKSVWSRLDGQWPDG 314
+ F L +Q P ++ + + V+L C+ A+P P + W + G
Sbjct: 1734 AE--KLFTLRVQVPPRIAGLDLEQVTAILNSSVSLPCDVHAHPNP-EVTWYKDSQALSLG 1790
Query: 315 ----LLASDNTLHFVHPLTFNYSGVYICKVTNSLGQRSDQKVIYIS 356
LL +TL + SG+Y C+ N+ G+ DQK++ +S
Sbjct: 1791 EEVFLLPGTHTLQLGRA-RLSDSGMYTCEALNAAGR--DQKLVQLS 1833
Score = 35.8 bits (81), Expect = 0.10
Identities = 63/252 (25%), Positives = 96/252 (38%), Gaps = 49/252 (19%)
Query: 142 DSGKYICKAVTFPLGNAQSSTTVTVLVEPTVSLIKGPDSLIDGG--------NETVAAIC 193
D+G+Y C VT LG A + V VL+ P++S D L + G N T+ C
Sbjct: 1415 DAGQYTC-VVTNELGEAVKNYHVEVLIPPSISK---DDPLGEVGVKEVKTKVNSTLTLEC 1470
Query: 194 IAATGKPVAHIDWEGDLGEMESTTTSFPNETATIISQYKLF---PTRFARGRRITCVVKH 250
+ P I W D G+ + P+ ++ + +L PT+ + R CV +
Sbjct: 1471 -ESWAVPPPTIRWYKD-GQPVT-----PSSRLQVLGEGRLLQIQPTQVSDSGRYLCVATN 1523
Query: 251 PALEKDIRYSFIL----------DIQYAPEV---------SVTGYDGNWFVGRKGVNLKC 291
A E D ++ ++ D A E+ VT Y V L C
Sbjct: 1524 VAGEDDQDFNVLIQVPPMFQKVGDFSAAFEILSREEEARGGVTEY--REIVENNPAYLYC 1581
Query: 292 NADANPPPFKSVWSRLDGQWPDG----LLASDNTLHFVHPLTFNYSGVYICKVTNSLGQR 347
+ +A PPP W R D G +L L N +G Y CK +N +G+
Sbjct: 1582 DTNAIPPP-DLTWYREDQPLSAGDEVSVLQGGRVLQIPLVRAEN-AGRYSCKASNEVGED 1639
Query: 348 SDQKVIYISDPP 359
+ + PP
Sbjct: 1640 WLHYELLVLTPP 1651
Score = 34.7 bits (78), Expect = 0.23
Identities = 22/81 (27%), Positives = 40/81 (49%), Gaps = 4/81 (4%)
Query: 126 YSLNDATITLHNIGFSDSGKYICKAVTFPLGNAQSSTTVTVLVEPTVSLIKGPDSLIDGG 185
+ L + ++T+H D+G+Y C A +G A+ + VL V ++ D + G
Sbjct: 3075 HQLQNGSLTIHRTERDDAGRYQCLAEN-EMGVAK-KVVILVLQSAPVFQVEPQDMTVRSG 3132
Query: 186 NETVAAICIAATGKPVAHIDW 206
++ A+ ATG+P I+W
Sbjct: 3133 DD--VALRCQATGEPTPTIEW 3151
Score = 34.3 bits (77), Expect = 0.30
Identities = 53/235 (22%), Positives = 90/235 (38%), Gaps = 32/235 (13%)
Query: 141 SDSGKYICKAVTFPLGNAQSSTTVTVLVEPTVSLIKGPDSLIDGGNETVAAICIAATGKP 200
+ G Y C+ +GN+ + V V P ++ + P + + + VA + ATGKP
Sbjct: 1037 AQEGTYTCECSNV-VGNSSQDLQLEVHVPPQIAGPREPPTQVSVVQDGVATLECNATGKP 1095
Query: 201 VAHIDWEGD-------LG-EMESTTTSFPNETATIISQYKLFPTRFARGRRITCVVKHPA 252
+ WE D LG ++++ S E A + A R +CV ++ A
Sbjct: 1096 PPTVTWERDGQPVGAELGLQLQNQGQSLHVERA-----------QAAHTGRYSCVAENLA 1144
Query: 253 LEKDIRYSFILDIQYAPEV--SVTGYDGNWFVGRKGVNLKCNADANPPPFKSVWSRLDGQ 310
+ + F L + PE+ + + L C A PPP W R G+
Sbjct: 1145 GRAERK--FELSVLVPPELIGDLDPLTNITAALHSPLTLLCEAMGIPPP-AIRWFR--GE 1199
Query: 311 WP-----DGLLASDNTLHFVHPLTFNYSGVYICKVTNSLGQRSDQKVIYISDPPT 360
P D L + + + SG+Y C +N G+ + + PP+
Sbjct: 1200 EPVSPGEDTYLLAGGWMLKMTQTQEQDSGLYSCLASNEAGEARRNFSVEVLVPPS 1254
Score = 33.9 bits (76), Expect = 0.40
Identities = 58/236 (24%), Positives = 90/236 (38%), Gaps = 30/236 (12%)
Query: 141 SDSGKYICKAVTFPLGNAQSSTTVTVLVEPTVSLIKGPDSLIDGG-----NETVAAICIA 195
S +G Y C A +G ++VL+ PT+ + G + D N ++ IC
Sbjct: 1318 SSAGHYSCIAAN-AVGEKTKHFQLSVLLAPTI--LGGAEDSADEEVTVTVNNPISLIC-E 1373
Query: 196 ATGKPVAHIDWEGDLGEMESTTTSFPNETATIISQYKLFPTRFARGRRITCVVKHPALEK 255
A P +I W D E++ + ++ + + TCVV + E
Sbjct: 1374 ALAFPSPNITWMKDGAPFEASRNI---QLLPGTHGLQILNAQKEDAGQYTCVVTNELGEA 1430
Query: 256 DIRYSFILDIQYAPEVSVTGYDGNWFVGRKGVN--------LKCNADANPPPFKSVWSRL 307
Y +++ P +S G VG K V L+C + A PPP W +
Sbjct: 1431 VKNYH--VEVLIPPSISKDDPLGE--VGVKEVKTKVNSTLTLECESWAVPPPTIR-WYK- 1484
Query: 308 DGQ--WPDGLLA--SDNTLHFVHPLTFNYSGVYICKVTNSLGQRSDQKVIYISDPP 359
DGQ P L + L + P + SG Y+C TN G+ + I PP
Sbjct: 1485 DGQPVTPSSRLQVLGEGRLLQIQPTQVSDSGRYLCVATNVAGEDDQDFNVLIQVPP 1540
Score = 33.5 bits (75), Expect = 0.52
Identities = 51/236 (21%), Positives = 92/236 (38%), Gaps = 23/236 (9%)
Query: 133 ITLHNIGFSDSGKYICKAVTFPLGNAQSSTTVTVLVEPTVSLIKGPDSLIDGGNETVAAI 192
+TL + SDSG+Y C AV+ +G + + V + P++ + S++ NE+VA
Sbjct: 844 LTLASARASDSGRYSCVAVS-AVGEDRQDVVLQVHMPPSILGEELNVSVV--ANESVALE 900
Query: 193 CIAATGKPVAHIDWEGDLGEMESTTTSFPNETATIISQYKLFPTRFAR---GRRITCVVK 249
C + P + W D +E P + + L A TC
Sbjct: 901 C-QSHAMPPPVLSWWKDGRPLE------PRPGVHLSADKALLQVDRADVWDAGHYTCEAL 953
Query: 250 HPALEKDIRYSFILDIQYAPEVSVTGYDGNWFVGRKGVNLKCNADANPPPFKSVWSRLDG 309
+ A + Y+ L++ AP + + + R+G + + PF + R DG
Sbjct: 954 NQAGRSEKHYN--LNVWVAPVFPLR--ESHTLTVREGHPTSLSCECRGVPFPKISWRKDG 1009
Query: 310 QWPDGL------LASDNTLHFVHPLTFNYSGVYICKVTNSLGQRSDQKVIYISDPP 359
Q G +++ L ++ G Y C+ +N +G S + + PP
Sbjct: 1010 QPLPGEGAGLQHVSAVGRLLYLGQAQLAQEGTYTCECSNVVGNSSQDLQLEVHVPP 1065
Score = 32.0 bits (71), Expect = 1.5
Identities = 53/236 (22%), Positives = 88/236 (37%), Gaps = 23/236 (9%)
Query: 142 DSGKYICKAVTFPLGNAQSSTTVTVLVEPTVSL--IKGPDSLIDGGNETVAAICIAATGK 199
DSG Y C A G A+ + +V VLV P++ ++ ++DG +T +C TG
Sbjct: 1226 DSGLYSCLASN-EAGEARRNFSVEVLVPPSIENEDLEEVIKVLDG--QTAHLMC-NVTGH 1281
Query: 200 PVAHIDWEGDLGEMESTTTSFPNETATIISQYKLFPTRFARGRRITCVVKHPALEKDIRY 259
P + W D + + ++ ++ + +C+ + EK +
Sbjct: 1282 PQPKLTWFKDGRPLARGDAHHISPDGVLL---QVLQANLSSAGHYSCIAANAVGEKTKHF 1338
Query: 260 SFILDIQYAPEVSVTGYDGN----WFVGRKGVNLKCNADANPPPFKSVWSRLDGQWPDGL 315
L + AP + D ++L C A A P P W + DG P
Sbjct: 1339 Q--LSVLLAPTILGGAEDSADEEVTVTVNNPISLICEALAFPSP-NITWMK-DGA-PFEA 1393
Query: 316 LASDNTLHFVHPLTF-----NYSGVYICKVTNSLGQRSDQKVIYISDPPTTTTLQP 366
+ L H L +G Y C VTN LG+ + + PP+ + P
Sbjct: 1394 SRNIQLLPGTHGLQILNAQKEDAGQYTCVVTNELGEAVKNYHVEVLIPPSISKDDP 1449
Score = 30.8 bits (68), Expect = 3.4
Identities = 32/122 (26%), Positives = 52/122 (42%), Gaps = 21/122 (17%)
Query: 88 QISWEKIHGKSSQTVAVHHPQYGFSVQGEYQGRVLFKNYSLNDATITLHNIGFSDSGKYI 147
Q++W K G SS+ + H Q G +V L + ++ L ++ +DSG Y
Sbjct: 33 QVTWRK--GPSSEPL---HGQPGVAV--------------LEEGSLFLASVSPADSGDYE 73
Query: 148 CKAVTFPLGNAQSSTTVTVLVEPTVSLIKGPDSLIDGGNETVAAICIAATGKPVAHIDWE 207
C+A T +G+ + V V P++ G + + G + A G PV I W
Sbjct: 74 CQA-TNEVGSTSRRAKLVVYVPPSIR-EDGRKANVSGMAGQSLTLECDANGFPVPEIVWL 131
Query: 208 GD 209
D
Sbjct: 132 KD 133
Score = 30.4 bits (67), Expect = 4.4
Identities = 37/128 (28%), Positives = 50/128 (39%), Gaps = 22/128 (17%)
Query: 282 VGRKGVNLKCNADANPPPFKSVWSRLDGQWPDGLLASDNTLHFVHPLTFNYS-----GVY 336
VG K V L C DA P P + W + DGQ P L L L + G+Y
Sbjct: 1855 VGDKAV-LSCETDALPEPTVT-WYK-DGQ-PLVLAQRTQALRGGQRLEIQEAQVSDKGLY 1910
Query: 337 ICKVTNSLGQRSDQKVIYISDPPTTTTLQPTIQWHPSTADIEDLATEPKKLP-----FPL 391
CKV+N G+ + + PPT +P T + +A P L P
Sbjct: 1911 SCKVSNVAGEAVRTFTLTVQVPPTFE--------NPKTETVSQVAGSPLVLTCDVSGVPA 1962
Query: 392 STLATIKD 399
T+ +KD
Sbjct: 1963 PTVTWLKD 1970
Score = 29.6 bits (65), Expect = 7.5
Identities = 37/147 (25%), Positives = 61/147 (41%), Gaps = 27/147 (18%)
Query: 66 VTAVWGKNVSLKCLIEVNETITQISWEKIHGKSSQTVAVHHPQYGFSVQGEYQGRVLFKN 125
VTA+ +VSL C + + +++W K SQ +++ F + G +
Sbjct: 1756 VTAILNSSVSLPCDVHAHPN-PEVTWYK----DSQALSLGEEV--FLLPGTH-------- 1800
Query: 126 YSLNDATITLHNIGFSDSGKYICKAVTFPLGNAQSSTTVTVLVEPTV-SLIKGPDS--LI 182
T+ L SDSG Y C+A+ G Q ++VLV P +GP L+
Sbjct: 1801 ------TLQLGRARLSDSGMYTCEALN-AAGRDQKLVQLSVLVPPAFRQAPRGPQDAVLV 1853
Query: 183 DGGNETVAAICIAATGKPVAHIDWEGD 209
G++ V + A +P + W D
Sbjct: 1854 RVGDKAVLSCETDALPEPT--VTWYKD 1878
>gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 5065
Score = 54.3 bits (129), Expect = 3e-07
Identities = 73/316 (23%), Positives = 111/316 (35%), Gaps = 42/316 (13%)
Query: 126 YSLNDATITLHNIGFSDSGKYICKAVTFPLGNAQSSTTVTVLVEPTVSL-IKGPDSLIDG 184
+ L+ ++ L + SD+G Y C A P G TV VLV PT+ G +L+
Sbjct: 3268 FYLDGGSLVLKGLRASDAGAYTCVAHN-PAGEDARLHTVNVLVPPTIKQGADGSGTLVSR 3326
Query: 185 GNETVAAICIAATGKPVAHIDWEGD-LGEMESTTTSFPNETATIISQYKLFPTRFARGRR 243
E V +C G P H+ W D L S T T+ ++ + A
Sbjct: 3327 PGELVTMVC-PVRGSPPIHVSWLKDGLPLPLSQRTLLHGSGHTL----RISKVQLADAGI 3381
Query: 244 ITCVVKHPALEKDIRYSFILDIQYAPEVSVTGYDGNWFVGRKG-VNLKCNADANPPPFKS 302
TCV PA D +F L +Q P + + + V R V L C A P P S
Sbjct: 3382 FTCVAASPAGVAD--RNFTLQVQVPPVLEPVEFQNDVVVVRGSLVELPCEARGVPLPLVS 3439
Query: 303 VWSRLDGQWPDGLLASDNTLHFVHPLTFNYSGVYICKVTNSLGQRSDQKVIYISDPP--- 359
W + DG+ + + SG Y C + G+ + + +PP
Sbjct: 3440 -WMK-DGEPLLSQSLEQGPSLQLEAVGAGDSGTYSCVAVSEAGEARRHFQLTVMEPPHIE 3497
Query: 360 ---------------------TTTTLQPTIQWHPSTADIEDLATEPKKLPFPLSTLATIK 398
T QP I WH + L + + + ++
Sbjct: 3498 DSGQPTELSLTPGAPMELLCDAQGTPQPNITWHKDGQALTRLENNSR-----ATRVLRVR 3552
Query: 399 DDTIATIIASVVGGAL 414
D + T +A GA+
Sbjct: 3553 DAGLYTCLAESPAGAI 3568
Score = 53.5 bits (127), Expect = 5e-07
Identities = 56/227 (24%), Positives = 98/227 (43%), Gaps = 17/227 (7%)
Query: 126 YSLNDATITLHNIGFSDSGKYICKAVTFPLGNAQSSTTVTVLVEPTVSLIKGPDSLIDGG 185
Y+ + L SD+G Y CKA +G A+ +T + V V PT+ G ++
Sbjct: 1551 YTRGGRQLQLGRAQSSDAGVYTCKASN-AVGAAEKATRLDVYVPPTIEGAGGRPYVVKAV 1609
Query: 186 NETVAAICIAATGKPVAHIDWEGD-LGEMESTTTSFPNETATIISQYKLFPTRFARGRRI 244
A+ A G P + W + L ES + + + + +L A
Sbjct: 1610 AGRPVALECVARGHPSPTLSWHHEGLPVAESNESRLETDGSVL----RLESPGEASSGLY 1665
Query: 245 TCVVKHPALEKDIRYSFILDIQYAPEVSVTGYDGN--WFVGRKGVNLKCNADANPPPFKS 302
+CV PA E ++YS +++Q P++ V G VG+ + L C A +P P +
Sbjct: 1666 SCVASSPAGEAVLQYS--VEVQVPPQLLVAEGLGQVTTIVGQP-LELPCQASGSPVP--T 1720
Query: 303 VWSRLDGQWPDGL----LASDNTLHFVHPLTFNYSGVYICKVTNSLG 345
+ +G+ + L +AS T + + ++SG++ C+ TN G
Sbjct: 1721 IQWLQNGRPAEELAGVQVASQGTTLHIDHVELDHSGLFACQATNEAG 1767
Score = 52.8 bits (125), Expect = 8e-07
Identities = 58/236 (24%), Positives = 96/236 (40%), Gaps = 25/236 (10%)
Query: 141 SDSGKYICKAVTFP-LGNAQSSTTVTVLVEPTVSLIKGPDSLIDGGNETVAAICIAATGK 199
++ G Y C AV+ G A++ VT +P L+ P+ + G ET C G+
Sbjct: 489 AEEGTYECTAVSRAGTGRAKAQIVVT---DPPPQLVPAPNVTVSPG-ETAVLSC-RVLGE 543
Query: 200 PVAHIDWEGDLGEMESTTTSFPNETATIISQYKLFPTRFARGRRITCVVKHPALEKDIRY 259
++ W D + ++T + + PT G R CV + R
Sbjct: 544 APYNLTWVRDWRVLPASTGRVAQLADLSLEISGIIPTD---GGRYQCVASNA--NGVTRA 598
Query: 260 SFILDIQYAPEVSVTGYDGNWFVGRKGVNLKCNADANPPPFKSVWSRLDGQWPDGLLASD 319
S L ++ AP+VS+ ++ G + V + C+A P P S WSR L D
Sbjct: 599 SVWLLVREAPQVSIHTSSQHFSQGVE-VKVSCSASGYPTPHIS-WSR-----ESQALQED 651
Query: 320 NTLHFVHPLTFNYSGV-------YICKVTNSLGQRSDQKVIYISDPPTTTTLQPTI 368
+ +H T GV Y C+ TN +G + +Y +DPP+ + + +
Sbjct: 652 SRIHVDAQGTLIIQGVAPEDAGNYSCQATNEVGTDQETVTLYYTDPPSVSAVNAVV 707
Score = 48.1 bits (113), Expect = 2e-05
Identities = 59/227 (25%), Positives = 87/227 (38%), Gaps = 17/227 (7%)
Query: 141 SDSGKYICKAVTFPLGNAQSSTTVTVLVEPTVSLIKGPDSLIDGGNETVAAICIAATGKP 200
SD G Y CK V+ G A + T+TV V PT K G+ V ++ G P
Sbjct: 3096 SDKGLYSCK-VSNVAGEAVRTFTLTVQVPPTFENPKTETVSQVAGSPLVLTCDVS--GVP 3152
Query: 201 VAHIDWEGDLGEMESTTTSFPNETATIISQYKLFPTRFARGRRITCVVKHPALEKDIRYS 260
+ W D +ES+ + +L P A+ TCV ++ E R
Sbjct: 3153 APTVTWLKDRMPVESSAVHGVVSRGGRLQLSRLQP---AQAGTYTCVAENTQAEA--RKD 3207
Query: 261 FILDIQYAPEVSVTGYDGNWFVGR-KGVNLKCNADANPPPFKSVWSRLDG------QWPD 313
F++ + AP + +G V + V L C AD PPP W + DG P
Sbjct: 3208 FVVAVLVAPRIRSSGVAREHHVLEGQEVRLDCEADGQPPP-DVAWLK-DGSPLGQDMGPH 3265
Query: 314 GLLASDNTLHFVHPLTFNYSGVYICKVTNSLGQRSDQKVIYISDPPT 360
D + L + +G Y C N G+ + + + PPT
Sbjct: 3266 LRFYLDGGSLVLKGLRASDAGAYTCVAHNPAGEDARLHTVNVLVPPT 3312
Score = 47.0 bits (110), Expect = 5e-05
Identities = 65/250 (26%), Positives = 98/250 (39%), Gaps = 37/250 (14%)
Query: 132 TITLHNIGFSDSGKYICKAVTFPLGNAQSSTTVTVLVEPTVSLIKGPDSLIDGGNETVAA 191
++ L +G DSG Y C AV+ G A+ +TV+ P + P L +
Sbjct: 3457 SLQLEAVGAGDSGTYSCVAVS-EAGEARRHFQLTVMEPPHIEDSGQPTELSLTPGAPMEL 3515
Query: 192 ICIAATGKPVAHIDWEGDLGEMESTTTSFPNETATIISQYKLFPTRFARGRRITCVVKHP 251
+C A G P +I W D ++ T N AT + R TC+ + P
Sbjct: 3516 LC-DAQGTPQPNITWHKD---GQALTRLENNSRATRV-------LRVRDAGLYTCLAESP 3564
Query: 252 ALEKDIRYSFILDIQYAPEVSVTGYDGNWFV---GRKGVNLKCNADANPPPFKSVWSRLD 308
A I SF + +Q P ++ G G FV + L+C+ +A P P K W R
Sbjct: 3565 A--GAIEKSFRVRVQAPP--NIVGPRGPRFVVGLAPGQLVLECSVEAEPAP-KITWHR-- 3617
Query: 309 GQWPDGLLASDNTLHFVHP----------LTFNYSGVYICKVTNSLGQRSDQKVIYISDP 358
DG++ ++ H P L+ SG Y C N+ G S + I
Sbjct: 3618 ----DGIVLQEDA-HTQFPERGRFLQLQALSTADSGDYSCTARNAAGSTSVAFRVEIHTV 3672
Query: 359 PTTTTLQPTI 368
PT + P +
Sbjct: 3673 PTIRSGPPAV 3682
Score = 46.2 bits (108), Expect = 8e-05
Identities = 58/252 (23%), Positives = 98/252 (38%), Gaps = 25/252 (9%)
Query: 142 DSGKYICKAVTFPLGNAQSSTTVTVLVEPTVSLIKGPDSLIDGGNETVAAICIAATGKPV 201
D+G Y C A + P G + S V V P + +GP ++ + C + +P
Sbjct: 3553 DAGLYTCLAES-PAGAIEKSFRVRVQAPPNIVGPRGPRFVVGLAPGQLVLEC-SVEAEPA 3610
Query: 202 AHIDWEGD-LGEMESTTTSFPNETATIISQYKLFPTRFARGRRITCVVKHPALEKDIRYS 260
I W D + E T FP + +L A +C ++ A + +
Sbjct: 3611 PKITWHRDGIVLQEDAHTQFPERGRFL----QLQALSTADSGDYSCTARNAAGSTSV--A 3664
Query: 261 FILDIQYAPEVSVTGYDGNWFVGRKGVNLKCNADANPPPFKSVWSR----LDGQWPDGLL 316
F ++I P + N V + + L C AD P P S W + LD + P +
Sbjct: 3665 FRVEIHTVPTIRSGPPAVNVSVNQTAL-LPCQADGVPAPLVS-WRKDRVPLDPRSPRFEI 3722
Query: 317 ASDNTLHFVHPLTFNYSGVYICKVTNSLGQRSDQKVIYISDPPTTTTLQPTIQWHPSTAD 376
+ +L + P+ +G Y+C +NS G + + + +PP PS ++
Sbjct: 3723 LPEGSLR-IQPVLAQDAGHYLCLASNSAGSDRQGRDLRVLEPPAIA---------PSPSN 3772
Query: 377 IEDLATEPKKLP 388
+ A P LP
Sbjct: 3773 LTLTAHTPALLP 3784
Score = 42.4 bits (98), Expect = 0.001
Identities = 69/283 (24%), Positives = 109/283 (38%), Gaps = 44/283 (15%)
Query: 127 SLNDATITLHNIGFSDSGKYICKAVTFPLGNAQSSTTVTVLVEPTVSL---IKGPDSLID 183
S++ + + SD+G Y C A G+ + + V V P ++L + GP +
Sbjct: 1935 SVDGRVLRIEQAQLSDAGSYRCVASNVA-GSTELRYGLRVNVPPRITLPPSLPGPVLV-- 1991
Query: 184 GGNETVAAICIAATGKPVAHIDWEGDLGEMESTTTS----FPNETATIISQYKLFPTRFA 239
N V C ATG P + W D + T FP ++ R +
Sbjct: 1992 --NTPVRLTC-NATGAPSPTLMWLKDGNPVSPAGTPGLQVFPGGRVLTLAS-----ARAS 2043
Query: 240 RGRRITCVVKHPALEKDIRYSFILDIQYAPEVSVTGYDGNW-FVGRKGVNLKCNADANPP 298
R +CV E R +L + P S+ G + N V + V L+C + A PP
Sbjct: 2044 DSGRYSCVAVSAVGED--RQDVVLQVHMPP--SILGEELNVSVVANESVALECQSHAMPP 2099
Query: 299 PFKSVWSRLDGQ----WPDGLLASDNTLHFVHPLTFNYSGVYICKVTNSLGQRSDQKVIY 354
P S W DG+ P L++D L V +G Y C+ N G +
Sbjct: 2100 PVLSWWK--DGRPLEPRPGVHLSADKALLQVDRADVWDAGHYTCEALNQAGHSEKHYNLN 2157
Query: 355 ISDPPT-------TTTLQPTIQWHPSTADIEDLATEPKKLPFP 390
+ P T T++ + HP++ L+ E + +PFP
Sbjct: 2158 VWVAPVFPLRESHTLTVR---EGHPTS-----LSCECRGVPFP 2192
Score = 40.0 bits (92), Expect = 0.006
Identities = 35/118 (29%), Positives = 56/118 (47%), Gaps = 15/118 (12%)
Query: 246 CVVKHPALEKDIRYSFILDIQYAPEVSVTGYDGNWFVGRKGVNLKCNADANPPPFKSVWS 305
C +PA RY +L +Q P+V VG + ++L C A+ NP P S WS
Sbjct: 1099 CTASNPAGSASHRY--VLGVQVPPQVQPGPRVLKVLVG-EALDLNCVAEGNPEPQLS-WS 1154
Query: 306 R----LDGQWPDGLLASDNTLHFVHPLTFNYSGVYICKVTNSLGQRSDQKVIYISDPP 359
+ L G+ P G ++HF T + +G Y C+ +NS G + + + + +PP
Sbjct: 1155 KDGVVLQGRGPQG------SVHFAAIRTSD-AGRYRCEASNSAGVDAWEVELRVLEPP 1205
Score = 36.6 bits (83), Expect = 0.061
Identities = 50/226 (22%), Positives = 92/226 (40%), Gaps = 27/226 (11%)
Query: 142 DSGKYICKAVTFPLGNAQSSTTVTVLVEPTVSLIKGPDSLID----GGNETVAAICIAAT 197
++G+Y CKA +G + VL P + + + L++ + TV+ C A
Sbjct: 2815 NAGRYSCKASN-EVGEDWLHYELLVLTPPVI--LGDTEELVEEVTVNASSTVSLQC-PAL 2870
Query: 198 GKPVAHIDWEGDLGEMESTTTSFPNETATIISQYKLFPTRFAR---GRRITCVVKHPALE 254
G PV I W +++ P+ ++ ++ A CV ++ A
Sbjct: 2871 GNPVPTISW------LQNGLPFSPSPRLQVLEDGQVLQVSTAEVADAASYMCVAENQAGS 2924
Query: 255 KDIRYSFILDIQYAPEVSVTGYDGNWFVGRKGVNLKCNADANPPPFKSVWSRLDGQWPDG 314
+ F L +Q P ++ + + V+L C+ A+P P + W + G
Sbjct: 2925 AE--KLFTLRVQVPPRIAGLDLEQVTAILNSSVSLPCDVHAHPNP-EVTWYKDSQALSLG 2981
Query: 315 ----LLASDNTLHFVHPLTFNYSGVYICKVTNSLGQRSDQKVIYIS 356
LL +TL + SG+Y C+ N+ G+ DQK++ +S
Sbjct: 2982 EEVFLLPGTHTLQLGRA-RLSDSGMYTCEALNAAGR--DQKLVQLS 3024
Score = 35.8 bits (81), Expect = 0.10
Identities = 50/233 (21%), Positives = 92/233 (39%), Gaps = 28/233 (12%)
Query: 129 NDATITLHNIGFSDSGKYICKAVT-FPLGNAQSSTTVTVLVEPTVSLIKGPDSLIDGGNE 187
+ + ++ D Y+C+A F A++ VT P ++ +++G +
Sbjct: 843 DSGVLFFESVAPEDQAPYVCEARNVFGKVQAEARLIVTGHAPPQIASSAPTVRVLEG--Q 900
Query: 188 TVAAICIAATGKPVAHIDWEGDLGEMESTTTSFPNETATIISQYKLFPTRFARGR--RIT 245
V+ CI G+P+ W D + P +I + L R + R +
Sbjct: 901 PVSLPCIVLAGRPLPERHWLKDGRPLP------PGSRHSIRADGSLHLDRALQEHAGRYS 954
Query: 246 CVVKHPA--LEKDIRYSFILDIQYAPEVSVTGYDGNWFVGRKGV--NLKCNADANPPPFK 301
CV + A +D+ L +Q P + T + +GV +L C A P P
Sbjct: 955 CVATNTAGSQHRDVE----LVVQVPPRIHPTA---THHITNEGVPASLPCVASGVPAP-T 1006
Query: 302 SVWSR----LDGQWPDGLLASDNTLHFVHPLTFNYSGVYICKVTNSLGQRSDQ 350
W++ L + P ++ + TL P + +G Y+C TN++G S +
Sbjct: 1007 ITWTKETNALTSRGPHYNVSKEGTLLIAQPSAQD-AGAYVCTATNTVGFSSQE 1058
Score = 35.8 bits (81), Expect = 0.10
Identities = 63/252 (25%), Positives = 96/252 (38%), Gaps = 49/252 (19%)
Query: 142 DSGKYICKAVTFPLGNAQSSTTVTVLVEPTVSLIKGPDSLIDGG--------NETVAAIC 193
D+G+Y C VT LG A + V VL+ P++S D L + G N T+ C
Sbjct: 2606 DAGQYTC-VVTNELGEAVKNYHVEVLIPPSISK---DDPLGEVGVKEVKTKVNSTLTLEC 2661
Query: 194 IAATGKPVAHIDWEGDLGEMESTTTSFPNETATIISQYKLF---PTRFARGRRITCVVKH 250
+ P I W D G+ + P+ ++ + +L PT+ + R CV +
Sbjct: 2662 -ESWAVPPPTIRWYKD-GQPVT-----PSSRLQVLGEGRLLQIQPTQVSDSGRYLCVATN 2714
Query: 251 PALEKDIRYSFIL----------DIQYAPEV---------SVTGYDGNWFVGRKGVNLKC 291
A E D ++ ++ D A E+ VT Y V L C
Sbjct: 2715 VAGEDDQDFNVLIQVPPMFQKVGDFSAAFEILSREEEARGGVTEY--REIVENNPAYLYC 2772
Query: 292 NADANPPPFKSVWSRLDGQWPDG----LLASDNTLHFVHPLTFNYSGVYICKVTNSLGQR 347
+ +A PPP W R D G +L L N +G Y CK +N +G+
Sbjct: 2773 DTNAIPPP-DLTWYREDQPLSAGDEVSVLQGGRVLQIPLVRAEN-AGRYSCKASNEVGED 2830
Query: 348 SDQKVIYISDPP 359
+ + PP
Sbjct: 2831 WLHYELLVLTPP 2842
Score = 34.7 bits (78), Expect = 0.23
Identities = 22/81 (27%), Positives = 40/81 (49%), Gaps = 4/81 (4%)
Query: 126 YSLNDATITLHNIGFSDSGKYICKAVTFPLGNAQSSTTVTVLVEPTVSLIKGPDSLIDGG 185
+ L + ++T+H D+G+Y C A +G A+ + VL V ++ D + G
Sbjct: 4266 HQLQNGSLTIHRTERDDAGRYQCLAEN-EMGVAK-KVVILVLQSAPVFQVEPQDMTVRSG 4323
Query: 186 NETVAAICIAATGKPVAHIDW 206
++ A+ ATG+P I+W
Sbjct: 4324 DD--VALRCQATGEPTPTIEW 4342
Score = 34.3 bits (77), Expect = 0.30
Identities = 53/235 (22%), Positives = 90/235 (38%), Gaps = 32/235 (13%)
Query: 141 SDSGKYICKAVTFPLGNAQSSTTVTVLVEPTVSLIKGPDSLIDGGNETVAAICIAATGKP 200
+ G Y C+ +GN+ + V V P ++ + P + + + VA + ATGKP
Sbjct: 2228 AQEGTYTCECSNV-VGNSSQDLQLEVHVPPQIAGPREPPTQVSVVQDGVATLECNATGKP 2286
Query: 201 VAHIDWEGD-------LG-EMESTTTSFPNETATIISQYKLFPTRFARGRRITCVVKHPA 252
+ WE D LG ++++ S E A + A R +CV ++ A
Sbjct: 2287 PPTVTWERDGQPVGAELGLQLQNQGQSLHVERA-----------QAAHTGRYSCVAENLA 2335
Query: 253 LEKDIRYSFILDIQYAPEV--SVTGYDGNWFVGRKGVNLKCNADANPPPFKSVWSRLDGQ 310
+ + F L + PE+ + + L C A PPP W R G+
Sbjct: 2336 GRAERK--FELSVLVPPELIGDLDPLTNITAALHSPLTLLCEAMGIPPP-AIRWFR--GE 2390
Query: 311 WP-----DGLLASDNTLHFVHPLTFNYSGVYICKVTNSLGQRSDQKVIYISDPPT 360
P D L + + + SG+Y C +N G+ + + PP+
Sbjct: 2391 EPVSPGEDTYLLAGGWMLKMTQTQEQDSGLYSCLASNEAGEARRNFSVEVLVPPS 2445
Score = 33.9 bits (76), Expect = 0.40
Identities = 38/141 (26%), Positives = 59/141 (41%), Gaps = 22/141 (15%)
Query: 69 VWGKNVSLKCLIEVNETITQISWEKIHGKSSQTVAVHHPQYGFSVQGEYQGRVLFKNYSL 128
V G+N SL C Q++W K G SS+ + H Q G +V L
Sbjct: 1219 VAGENASLPCPARGTPK-PQVTWRK--GPSSEPL---HGQPGVAV--------------L 1258
Query: 129 NDATITLHNIGFSDSGKYICKAVTFPLGNAQSSTTVTVLVEPTVSLIKGPDSLIDGGNET 188
+ ++ L ++ +DSG Y C+A T +G+ + V V P++ G + + G
Sbjct: 1259 EEGSLFLASVSPADSGDYECQA-TNEVGSTSRRAKLVVYVPPSIR-EDGRKANVSGMAGQ 1316
Query: 189 VAAICIAATGKPVAHIDWEGD 209
+ A G PV I W D
Sbjct: 1317 SLTLECDANGFPVPEIVWLKD 1337
Score = 33.9 bits (76), Expect = 0.40
Identities = 58/236 (24%), Positives = 90/236 (38%), Gaps = 30/236 (12%)
Query: 141 SDSGKYICKAVTFPLGNAQSSTTVTVLVEPTVSLIKGPDSLIDGG-----NETVAAICIA 195
S +G Y C A +G ++VL+ PT+ + G + D N ++ IC
Sbjct: 2509 SSAGHYSCIAAN-AVGEKTKHFQLSVLLAPTI--LGGAEDSADEEVTVTVNNPISLIC-E 2564
Query: 196 ATGKPVAHIDWEGDLGEMESTTTSFPNETATIISQYKLFPTRFARGRRITCVVKHPALEK 255
A P +I W D E++ + ++ + + TCVV + E
Sbjct: 2565 ALAFPSPNITWMKDGAPFEASRNI---QLLPGTHGLQILNAQKEDAGQYTCVVTNELGEA 2621
Query: 256 DIRYSFILDIQYAPEVSVTGYDGNWFVGRKGVN--------LKCNADANPPPFKSVWSRL 307
Y +++ P +S G VG K V L+C + A PPP W +
Sbjct: 2622 VKNYH--VEVLIPPSISKDDPLGE--VGVKEVKTKVNSTLTLECESWAVPPPTIR-WYK- 2675
Query: 308 DGQ--WPDGLLA--SDNTLHFVHPLTFNYSGVYICKVTNSLGQRSDQKVIYISDPP 359
DGQ P L + L + P + SG Y+C TN G+ + I PP
Sbjct: 2676 DGQPVTPSSRLQVLGEGRLLQIQPTQVSDSGRYLCVATNVAGEDDQDFNVLIQVPP 2731
Score = 33.5 bits (75), Expect = 0.52
Identities = 51/236 (21%), Positives = 92/236 (38%), Gaps = 23/236 (9%)
Query: 133 ITLHNIGFSDSGKYICKAVTFPLGNAQSSTTVTVLVEPTVSLIKGPDSLIDGGNETVAAI 192
+TL + SDSG+Y C AV+ +G + + V + P++ + S++ NE+VA
Sbjct: 2035 LTLASARASDSGRYSCVAVS-AVGEDRQDVVLQVHMPPSILGEELNVSVV--ANESVALE 2091
Query: 193 CIAATGKPVAHIDWEGDLGEMESTTTSFPNETATIISQYKLFPTRFAR---GRRITCVVK 249
C + P + W D +E P + + L A TC
Sbjct: 2092 C-QSHAMPPPVLSWWKDGRPLE------PRPGVHLSADKALLQVDRADVWDAGHYTCEAL 2144
Query: 250 HPALEKDIRYSFILDIQYAPEVSVTGYDGNWFVGRKGVNLKCNADANPPPFKSVWSRLDG 309
+ A + Y+ L++ AP + + + R+G + + PF + R DG
Sbjct: 2145 NQAGHSEKHYN--LNVWVAPVFPLR--ESHTLTVREGHPTSLSCECRGVPFPKISWRKDG 2200
Query: 310 QWPDGL------LASDNTLHFVHPLTFNYSGVYICKVTNSLGQRSDQKVIYISDPP 359
Q G +++ L ++ G Y C+ +N +G S + + PP
Sbjct: 2201 QPLPGEGAGLQHVSAVGRLLYLGQAQLAQEGTYTCECSNVVGNSSQDLQLEVHVPP 2256
Score = 32.0 bits (71), Expect = 1.5
Identities = 53/236 (22%), Positives = 88/236 (37%), Gaps = 23/236 (9%)
Query: 142 DSGKYICKAVTFPLGNAQSSTTVTVLVEPTVSL--IKGPDSLIDGGNETVAAICIAATGK 199
DSG Y C A G A+ + +V VLV P++ ++ ++DG +T +C TG
Sbjct: 2417 DSGLYSCLASN-EAGEARRNFSVEVLVPPSIENEDLEEVIKVLDG--QTAHLMC-NVTGH 2472
Query: 200 PVAHIDWEGDLGEMESTTTSFPNETATIISQYKLFPTRFARGRRITCVVKHPALEKDIRY 259
P + W D + + ++ ++ + +C+ + EK +
Sbjct: 2473 PQPKLTWFKDGRPLARGDAHHISPDGVLL---QVLQANLSSAGHYSCIAANAVGEKTKHF 2529
Query: 260 SFILDIQYAPEVSVTGYDGN----WFVGRKGVNLKCNADANPPPFKSVWSRLDGQWPDGL 315
L + AP + D ++L C A A P P W + DG P
Sbjct: 2530 Q--LSVLLAPTILGGAEDSADEEVTVTVNNPISLICEALAFPSP-NITWMK-DGA-PFEA 2584
Query: 316 LASDNTLHFVHPLTF-----NYSGVYICKVTNSLGQRSDQKVIYISDPPTTTTLQP 366
+ L H L +G Y C VTN LG+ + + PP+ + P
Sbjct: 2585 SRNIQLLPGTHGLQILNAQKEDAGQYTCVVTNELGEAVKNYHVEVLIPPSISKDDP 2640
Score = 30.4 bits (67), Expect = 4.4
Identities = 37/128 (28%), Positives = 50/128 (39%), Gaps = 22/128 (17%)
Query: 282 VGRKGVNLKCNADANPPPFKSVWSRLDGQWPDGLLASDNTLHFVHPLTFNYS-----GVY 336
VG K V L C DA P P + W + DGQ P L L L + G+Y
Sbjct: 3046 VGDKAV-LSCETDALPEPTVT-WYK-DGQ-PLVLAQRTQALRGGQRLEIQEAQVSDKGLY 3101
Query: 337 ICKVTNSLGQRSDQKVIYISDPPTTTTLQPTIQWHPSTADIEDLATEPKKLP-----FPL 391
CKV+N G+ + + PPT +P T + +A P L P
Sbjct: 3102 SCKVSNVAGEAVRTFTLTVQVPPTFE--------NPKTETVSQVAGSPLVLTCDVSGVPA 3153
Query: 392 STLATIKD 399
T+ +KD
Sbjct: 3154 PTVTWLKD 3161
Score = 29.6 bits (65), Expect = 7.5
Identities = 37/147 (25%), Positives = 61/147 (41%), Gaps = 27/147 (18%)
Query: 66 VTAVWGKNVSLKCLIEVNETITQISWEKIHGKSSQTVAVHHPQYGFSVQGEYQGRVLFKN 125
VTA+ +VSL C + + +++W K SQ +++ F + G +
Sbjct: 2947 VTAILNSSVSLPCDVHAHPN-PEVTWYK----DSQALSLGEEV--FLLPGTH-------- 2991
Query: 126 YSLNDATITLHNIGFSDSGKYICKAVTFPLGNAQSSTTVTVLVEPTV-SLIKGPDS--LI 182
T+ L SDSG Y C+A+ G Q ++VLV P +GP L+
Sbjct: 2992 ------TLQLGRARLSDSGMYTCEALN-AAGRDQKLVQLSVLVPPAFRQAPRGPQDAVLV 3044
Query: 183 DGGNETVAAICIAATGKPVAHIDWEGD 209
G++ V + A +P + W D
Sbjct: 3045 RVGDKAVLSCETDALPEPT--VTWYKD 3069
>gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 3783
Score = 54.3 bits (129), Expect = 3e-07
Identities = 73/316 (23%), Positives = 111/316 (35%), Gaps = 42/316 (13%)
Query: 126 YSLNDATITLHNIGFSDSGKYICKAVTFPLGNAQSSTTVTVLVEPTVSL-IKGPDSLIDG 184
+ L+ ++ L + SD+G Y C A P G TV VLV PT+ G +L+
Sbjct: 1986 FYLDGGSLVLKGLRASDAGAYTCVAHN-PAGEDARLHTVNVLVPPTIKQGADGSGTLVSR 2044
Query: 185 GNETVAAICIAATGKPVAHIDWEGD-LGEMESTTTSFPNETATIISQYKLFPTRFARGRR 243
E V +C G P H+ W D L S T T+ ++ + A
Sbjct: 2045 PGELVTMVC-PVRGSPPIHVSWLKDGLPLPLSQRTLLHGSGHTL----RISKVQLADAGI 2099
Query: 244 ITCVVKHPALEKDIRYSFILDIQYAPEVSVTGYDGNWFVGRKG-VNLKCNADANPPPFKS 302
TCV PA D +F L +Q P + + + V R V L C A P P S
Sbjct: 2100 FTCVAASPAGVAD--RNFTLQVQVPPVLEPVEFQNDVVVVRGSLVELPCEARGVPLPLVS 2157
Query: 303 VWSRLDGQWPDGLLASDNTLHFVHPLTFNYSGVYICKVTNSLGQRSDQKVIYISDPP--- 359
W + DG+ + + SG Y C + G+ + + +PP
Sbjct: 2158 -WMK-DGEPLLSQSLEQGPSLQLEAVGAGDSGTYSCVAVSEAGEARRHFQLTVMEPPHIE 2215
Query: 360 ---------------------TTTTLQPTIQWHPSTADIEDLATEPKKLPFPLSTLATIK 398
T QP I WH + L + + + ++
Sbjct: 2216 DSGQPTELSLTPGAPMELLCDAQGTPQPNITWHKDGQALTRLENNSR-----ATRVLRVR 2270
Query: 399 DDTIATIIASVVGGAL 414
D + T +A GA+
Sbjct: 2271 DAGLYTCLAESPAGAI 2286
Score = 53.5 bits (127), Expect = 5e-07
Identities = 56/227 (24%), Positives = 98/227 (43%), Gaps = 17/227 (7%)
Query: 126 YSLNDATITLHNIGFSDSGKYICKAVTFPLGNAQSSTTVTVLVEPTVSLIKGPDSLIDGG 185
Y+ + L SD+G Y CKA +G A+ +T + V V PT+ G ++
Sbjct: 269 YTRGGRQLQLGRAQSSDAGVYTCKASN-AVGAAEKATRLDVYVPPTIEGAGGRPYVVKAV 327
Query: 186 NETVAAICIAATGKPVAHIDWEGD-LGEMESTTTSFPNETATIISQYKLFPTRFARGRRI 244
A+ A G P + W + L ES + + + + +L A
Sbjct: 328 AGRPVALECVARGHPSPTLSWHHEGLPVAESNESRLETDGSVL----RLESPGEASSGLY 383
Query: 245 TCVVKHPALEKDIRYSFILDIQYAPEVSVTGYDGN--WFVGRKGVNLKCNADANPPPFKS 302
+CV PA E ++YS +++Q P++ V G VG+ + L C A +P P +
Sbjct: 384 SCVASSPAGEAVLQYS--VEVQVPPQLLVAEGLGQVTTIVGQP-LELPCQASGSPVP--T 438
Query: 303 VWSRLDGQWPDGL----LASDNTLHFVHPLTFNYSGVYICKVTNSLG 345
+ +G+ + L +AS T + + ++SG++ C+ TN G
Sbjct: 439 IQWLQNGRPAEELAGVQVASQGTTLHIDHVELDHSGLFACQATNEAG 485
Score = 48.1 bits (113), Expect = 2e-05
Identities = 59/227 (25%), Positives = 87/227 (38%), Gaps = 17/227 (7%)
Query: 141 SDSGKYICKAVTFPLGNAQSSTTVTVLVEPTVSLIKGPDSLIDGGNETVAAICIAATGKP 200
SD G Y CK V+ G A + T+TV V PT K G+ V ++ G P
Sbjct: 1814 SDKGLYSCK-VSNVAGEAVRTFTLTVQVPPTFENPKTETVSQVAGSPLVLTCDVS--GVP 1870
Query: 201 VAHIDWEGDLGEMESTTTSFPNETATIISQYKLFPTRFARGRRITCVVKHPALEKDIRYS 260
+ W D +ES+ + +L P A+ TCV ++ E R
Sbjct: 1871 APTVTWLKDRMPVESSAVHGVVSRGGRLQLSRLQP---AQAGTYTCVAENTQAEA--RKD 1925
Query: 261 FILDIQYAPEVSVTGYDGNWFVGR-KGVNLKCNADANPPPFKSVWSRLDG------QWPD 313
F++ + AP + +G V + V L C AD PPP W + DG P
Sbjct: 1926 FVVAVLVAPRIRSSGVAREHHVLEGQEVRLDCEADGQPPP-DVAWLK-DGSPLGQDMGPH 1983
Query: 314 GLLASDNTLHFVHPLTFNYSGVYICKVTNSLGQRSDQKVIYISDPPT 360
D + L + +G Y C N G+ + + + PPT
Sbjct: 1984 LRFYLDGGSLVLKGLRASDAGAYTCVAHNPAGEDARLHTVNVLVPPT 2030
Score = 47.0 bits (110), Expect = 5e-05
Identities = 65/250 (26%), Positives = 98/250 (39%), Gaps = 37/250 (14%)
Query: 132 TITLHNIGFSDSGKYICKAVTFPLGNAQSSTTVTVLVEPTVSLIKGPDSLIDGGNETVAA 191
++ L +G DSG Y C AV+ G A+ +TV+ P + P L +
Sbjct: 2175 SLQLEAVGAGDSGTYSCVAVS-EAGEARRHFQLTVMEPPHIEDSGQPTELSLTPGAPMEL 2233
Query: 192 ICIAATGKPVAHIDWEGDLGEMESTTTSFPNETATIISQYKLFPTRFARGRRITCVVKHP 251
+C A G P +I W D ++ T N AT + R TC+ + P
Sbjct: 2234 LC-DAQGTPQPNITWHKD---GQALTRLENNSRATRV-------LRVRDAGLYTCLAESP 2282
Query: 252 ALEKDIRYSFILDIQYAPEVSVTGYDGNWFV---GRKGVNLKCNADANPPPFKSVWSRLD 308
A I SF + +Q P ++ G G FV + L+C+ +A P P K W R
Sbjct: 2283 A--GAIEKSFRVRVQAPP--NIVGPRGPRFVVGLAPGQLVLECSVEAEPAP-KITWHR-- 2335
Query: 309 GQWPDGLLASDNTLHFVHP----------LTFNYSGVYICKVTNSLGQRSDQKVIYISDP 358
DG++ ++ H P L+ SG Y C N+ G S + I
Sbjct: 2336 ----DGIVLQEDA-HTQFPERGRFLQLQALSTADSGDYSCTARNAAGSTSVAFRVEIHTV 2390
Query: 359 PTTTTLQPTI 368
PT + P +
Sbjct: 2391 PTIRSGPPAV 2400
Score = 46.2 bits (108), Expect = 8e-05
Identities = 58/252 (23%), Positives = 98/252 (38%), Gaps = 25/252 (9%)
Query: 142 DSGKYICKAVTFPLGNAQSSTTVTVLVEPTVSLIKGPDSLIDGGNETVAAICIAATGKPV 201
D+G Y C A + P G + S V V P + +GP ++ + C + +P
Sbjct: 2271 DAGLYTCLAES-PAGAIEKSFRVRVQAPPNIVGPRGPRFVVGLAPGQLVLEC-SVEAEPA 2328
Query: 202 AHIDWEGD-LGEMESTTTSFPNETATIISQYKLFPTRFARGRRITCVVKHPALEKDIRYS 260
I W D + E T FP + +L A +C ++ A + +
Sbjct: 2329 PKITWHRDGIVLQEDAHTQFPERGRFL----QLQALSTADSGDYSCTARNAAGSTSV--A 2382
Query: 261 FILDIQYAPEVSVTGYDGNWFVGRKGVNLKCNADANPPPFKSVWSR----LDGQWPDGLL 316
F ++I P + N V + + L C AD P P S W + LD + P +
Sbjct: 2383 FRVEIHTVPTIRSGPPAVNVSVNQTAL-LPCQADGVPAPLVS-WRKDRVPLDPRSPRFEI 2440
Query: 317 ASDNTLHFVHPLTFNYSGVYICKVTNSLGQRSDQKVIYISDPPTTTTLQPTIQWHPSTAD 376
+ +L + P+ +G Y+C +NS G + + + +PP PS ++
Sbjct: 2441 LPEGSLR-IQPVLAQDAGHYLCLASNSAGSDRQGRDLRVLEPPAIA---------PSPSN 2490
Query: 377 IEDLATEPKKLP 388
+ A P LP
Sbjct: 2491 LTLTAHTPALLP 2502
Score = 41.6 bits (96), Expect = 0.002
Identities = 69/283 (24%), Positives = 108/283 (38%), Gaps = 44/283 (15%)
Query: 127 SLNDATITLHNIGFSDSGKYICKAVTFPLGNAQSSTTVTVLVEPTVSL---IKGPDSLID 183
S++ + + SD+G Y C A G+ + + V V P ++L + GP +
Sbjct: 653 SVDGRVLRIEQAQLSDAGSYRCVASNVA-GSTELRYGLRVNVPPRITLPPSLPGPVLV-- 709
Query: 184 GGNETVAAICIAATGKPVAHIDWEGDLGEMESTTTS----FPNETATIISQYKLFPTRFA 239
N V C ATG P + W D + T FP ++ R +
Sbjct: 710 --NTPVRLTC-NATGAPSPTLMWLKDGNPVSPAGTPGLQVFPGGRVLTLAS-----ARAS 761
Query: 240 RGRRITCVVKHPALEKDIRYSFILDIQYAPEVSVTGYDGNW-FVGRKGVNLKCNADANPP 298
R +CV E R +L + P S+ G + N V + V L+C + A PP
Sbjct: 762 DSGRYSCVAVSAVGED--RQDVVLQVHMPP--SILGEELNVSVVANESVALECQSHAMPP 817
Query: 299 PFKSVWSRLDGQ----WPDGLLASDNTLHFVHPLTFNYSGVYICKVTNSLGQRSDQKVIY 354
P S W DG+ P L++D L V +G Y C+ N G +
Sbjct: 818 PVLSWWK--DGRPLEPRPGVHLSADKALLQVDRADVWDAGHYTCEALNQAGHSEKHYNLN 875
Query: 355 ISDPPT-------TTTLQPTIQWHPSTADIEDLATEPKKLPFP 390
+ P T T++ + HP+ L+ E + +PFP
Sbjct: 876 VWVAPVFPLRESHTLTVR---EGHPTR-----LSCECRGVPFP 910
Score = 37.0 bits (84), Expect = 0.047
Identities = 63/252 (25%), Positives = 96/252 (38%), Gaps = 49/252 (19%)
Query: 142 DSGKYICKAVTFPLGNAQSSTTVTVLVEPTVSLIKGPDSLIDGG--------NETVAAIC 193
D+G+Y C VT LG A + V VL+ P++S D L + G N T+ C
Sbjct: 1324 DAGQYTC-VVTNELGEAVKNYHVEVLIPPSISK---DDPLAEVGVKEVKTKVNSTLTLEC 1379
Query: 194 IAATGKPVAHIDWEGDLGEMESTTTSFPNETATIISQYKLF---PTRFARGRRITCVVKH 250
+ P I W D G+ + P+ ++ + +L PT+ + R CV +
Sbjct: 1380 -ESWAVPPPTIRWYKD-GQPVT-----PSSRLQVLGEGRLLQIQPTQVSDSGRYLCVATN 1432
Query: 251 PALEKDIRYSFIL----------DIQYAPEV---------SVTGYDGNWFVGRKGVNLKC 291
A E D ++ ++ D A E+ VT Y V L C
Sbjct: 1433 VAGEDDQDFNVLIQVPPMFQKVGDFSAAFEILSREEEARGGVTEY--REIVENNPAYLYC 1490
Query: 292 NADANPPPFKSVWSRLDGQWPDG----LLASDNTLHFVHPLTFNYSGVYICKVTNSLGQR 347
+ +A PPP W R D G +L L N +G Y CK +N +G+
Sbjct: 1491 DTNAIPPP-DLTWYREDQPLSAGDEVSVLQGGRVLQIPLVRAEN-AGRYSCKASNEVGED 1548
Query: 348 SDQKVIYISDPP 359
+ + PP
Sbjct: 1549 WLHYELLVLTPP 1560
Score = 36.6 bits (83), Expect = 0.061
Identities = 50/226 (22%), Positives = 93/226 (41%), Gaps = 27/226 (11%)
Query: 142 DSGKYICKAVTFPLGNAQSSTTVTVLVEPTVSLIKGPDSLID----GGNETVAAICIAAT 197
++G+Y CKA +G + VL P + + + L++ + TV+ C A
Sbjct: 1533 NAGRYSCKASN-EVGEDWLHYELLVLTPPVI--LGDTEELVEEVTVNASSTVSLQC-PAL 1588
Query: 198 GKPVAHIDWEGDLGEMESTTTSFPNETATIISQYKLFPTRFAR---GRRITCVVKHPALE 254
G PV I W +++ P+ ++ ++ A CV ++ A
Sbjct: 1589 GNPVPTISW------LQNGLPFSPSPRLQVLEDGQVLQVSTAEVADAASYMCVAENQAGS 1642
Query: 255 KDIRYSFILDIQYAPEVSVTGYDGNWFVGRKGVNLKCNADANPPPFKSVWSRLDGQWPDG 314
+ F L +Q P ++ + + V+L C+ A+P P + W + G
Sbjct: 1643 AE--KLFTLRVQVPPRIAGLDLEQVTAILNSSVSLPCDVHAHPNP-EVTWYKDSQALSLG 1699
Query: 315 ----LLASDNTLHFVHPLTFNYSGVYICKVTNSLGQRSDQKVIYIS 356
LL +TL + + SG+Y C+ N+ G+ DQK++ +S
Sbjct: 1700 EEVFLLPGTHTLQ-LGRARLSDSGMYTCEALNAAGR--DQKLVQLS 1742
Score = 34.3 bits (77), Expect = 0.30
Identities = 51/236 (21%), Positives = 93/236 (39%), Gaps = 23/236 (9%)
Query: 133 ITLHNIGFSDSGKYICKAVTFPLGNAQSSTTVTVLVEPTVSLIKGPDSLIDGGNETVAAI 192
+TL + SDSG+Y C AV+ +G + + V + P++ + S++ NE+VA
Sbjct: 753 LTLASARASDSGRYSCVAVS-AVGEDRQDVVLQVHMPPSILGEELNVSVV--ANESVALE 809
Query: 193 CIAATGKPVAHIDWEGDLGEMESTTTSFPNETATIISQYKLFPTRFAR---GRRITCVVK 249
C + P + W D +E P + + L A TC
Sbjct: 810 C-QSHAMPPPVLSWWKDGRPLE------PRPGVHLSADKALLQVDRADVWDAGHYTCEAL 862
Query: 250 HPALEKDIRYSFILDIQYAPEVSVTGYDGNWFVGRKGVNLKCNADANPPPFKSVWSRLDG 309
+ A + Y+ L++ AP + + + R+G + + + PF + R DG
Sbjct: 863 NQAGHSEKHYN--LNVWVAPVFPLR--ESHTLTVREGHPTRLSCECRGVPFPKISWRKDG 918
Query: 310 QWPDGL------LASDNTLHFVHPLTFNYSGVYICKVTNSLGQRSDQKVIYISDPP 359
Q G +++ L ++ G Y C+ +N +G S + + PP
Sbjct: 919 QPLPGEGAGLQHVSAVGRLLYLGQAQLAQEGTYTCECSNVVGNSSQDLQLEVHVPP 974
Score = 34.3 bits (77), Expect = 0.30
Identities = 53/235 (22%), Positives = 90/235 (38%), Gaps = 32/235 (13%)
Query: 141 SDSGKYICKAVTFPLGNAQSSTTVTVLVEPTVSLIKGPDSLIDGGNETVAAICIAATGKP 200
+ G Y C+ +GN+ + V V P ++ + P + + + VA + ATGKP
Sbjct: 946 AQEGTYTCECSNV-VGNSSQDLQLEVHVPPQIAGPREPPTQVSVVQDGVATLECNATGKP 1004
Query: 201 VAHIDWEGD-------LG-EMESTTTSFPNETATIISQYKLFPTRFARGRRITCVVKHPA 252
+ WE D LG ++++ S E A + A R +CV ++ A
Sbjct: 1005 PPTVTWERDGQPVGAELGLQLQNQGQSLHVERA-----------QAAHTGRYSCVAENLA 1053
Query: 253 LEKDIRYSFILDIQYAPEV--SVTGYDGNWFVGRKGVNLKCNADANPPPFKSVWSRLDGQ 310
+ + F L + PE+ + + L C A PPP W R G+
Sbjct: 1054 GRAERK--FELSVLVPPELIGDLDPLTNITAALHSPLTLLCEAMGIPPP-AIRWFR--GE 1108
Query: 311 WP-----DGLLASDNTLHFVHPLTFNYSGVYICKVTNSLGQRSDQKVIYISDPPT 360
P D L + + + SG+Y C +N G+ + + PP+
Sbjct: 1109 EPVSPGEDTYLLAGGWMLKMTQTQEQDSGLYSCLASNEAGEARRNFSVEVLVPPS 1163
Score = 32.7 bits (73), Expect = 0.88
Identities = 58/236 (24%), Positives = 90/236 (38%), Gaps = 30/236 (12%)
Query: 141 SDSGKYICKAVTFPLGNAQSSTTVTVLVEPTVSLIKGPDSLIDGG-----NETVAAICIA 195
S +G Y C A +G ++VL+ PT+ + G + D N ++ IC
Sbjct: 1227 SSAGHYSCIAAN-AVGEKTKHFQLSVLLAPTI--LGGAEDSADEEVTVTVNNPISLIC-E 1282
Query: 196 ATGKPVAHIDWEGDLGEMESTTTSFPNETATIISQYKLFPTRFARGRRITCVVKHPALEK 255
A P +I W D E++ + ++ + + TCVV + E
Sbjct: 1283 ALAFPSPNITWMKDGAPFEASRNI---QLLPGTHGLQILNAQKEDAGQYTCVVTNELGEA 1339
Query: 256 DIRYSFILDIQYAPEVSVTGYDGNWFVGRKGVN--------LKCNADANPPPFKSVWSRL 307
Y +++ P +S D VG K V L+C + A PPP W +
Sbjct: 1340 VKNYH--VEVLIPPSISKD--DPLAEVGVKEVKTKVNSTLTLECESWAVPPPTIR-WYK- 1393
Query: 308 DGQ--WPDGLLA--SDNTLHFVHPLTFNYSGVYICKVTNSLGQRSDQKVIYISDPP 359
DGQ P L + L + P + SG Y+C TN G+ + I PP
Sbjct: 1394 DGQPVTPSSRLQVLGEGRLLQIQPTQVSDSGRYLCVATNVAGEDDQDFNVLIQVPP 1449
Score = 32.0 bits (71), Expect = 1.5
Identities = 53/236 (22%), Positives = 88/236 (37%), Gaps = 23/236 (9%)
Query: 142 DSGKYICKAVTFPLGNAQSSTTVTVLVEPTVSL--IKGPDSLIDGGNETVAAICIAATGK 199
DSG Y C A G A+ + +V VLV P++ ++ ++DG +T +C TG
Sbjct: 1135 DSGLYSCLASN-EAGEARRNFSVEVLVPPSIENEDLEEVIKVLDG--QTAHLMC-NVTGH 1190
Query: 200 PVAHIDWEGDLGEMESTTTSFPNETATIISQYKLFPTRFARGRRITCVVKHPALEKDIRY 259
P + W D + + ++ ++ + +C+ + EK +
Sbjct: 1191 PQPKLTWFKDGRPLARGDAHHISPDGVLL---QVLQANLSSAGHYSCIAANAVGEKTKHF 1247
Query: 260 SFILDIQYAPEVSVTGYDGN----WFVGRKGVNLKCNADANPPPFKSVWSRLDGQWPDGL 315
L + AP + D ++L C A A P P W + DG P
Sbjct: 1248 Q--LSVLLAPTILGGAEDSADEEVTVTVNNPISLICEALAFPSP-NITWMK-DGA-PFEA 1302
Query: 316 LASDNTLHFVHPLTF-----NYSGVYICKVTNSLGQRSDQKVIYISDPPTTTTLQP 366
+ L H L +G Y C VTN LG+ + + PP+ + P
Sbjct: 1303 SRNIQLLPGTHGLQILNAQKEDAGQYTCVVTNELGEAVKNYHVEVLIPPSISKDDP 1358
Score = 31.6 bits (70), Expect = 2.0
Identities = 21/81 (25%), Positives = 39/81 (48%), Gaps = 4/81 (4%)
Query: 126 YSLNDATITLHNIGFSDSGKYICKAVTFPLGNAQSSTTVTVLVEPTVSLIKGPDSLIDGG 185
+ L + ++T+ D+G+Y C A +G A+ + VL V ++ D + G
Sbjct: 2984 HQLQNGSLTIRRTERDDAGRYQCLAEN-EMGVAK-KVVILVLQSAPVFQVEPQDMTVRSG 3041
Query: 186 NETVAAICIAATGKPVAHIDW 206
++ A+ ATG+P I+W
Sbjct: 3042 DD--VALRCQATGEPTPTIEW 3060
Score = 30.4 bits (67), Expect = 4.4
Identities = 37/128 (28%), Positives = 50/128 (39%), Gaps = 22/128 (17%)
Query: 282 VGRKGVNLKCNADANPPPFKSVWSRLDGQWPDGLLASDNTLHFVHPLTFNYS-----GVY 336
VG K V L C DA P P + W + DGQ P L L L + G+Y
Sbjct: 1764 VGDKAV-LSCETDALPEPTVT-WYK-DGQ-PLVLAQRTQALRGGQRLEIQEAQVSDKGLY 1819
Query: 337 ICKVTNSLGQRSDQKVIYISDPPTTTTLQPTIQWHPSTADIEDLATEPKKLP-----FPL 391
CKV+N G+ + + PPT +P T + +A P L P
Sbjct: 1820 SCKVSNVAGEAVRTFTLTVQVPPTFE--------NPKTETVSQVAGSPLVLTCDVSGVPA 1871
Query: 392 STLATIKD 399
T+ +KD
Sbjct: 1872 PTVTWLKD 1879
Score = 29.6 bits (65), Expect = 7.5
Identities = 37/147 (25%), Positives = 61/147 (41%), Gaps = 27/147 (18%)
Query: 66 VTAVWGKNVSLKCLIEVNETITQISWEKIHGKSSQTVAVHHPQYGFSVQGEYQGRVLFKN 125
VTA+ +VSL C + + +++W K SQ +++ F + G +
Sbjct: 1665 VTAILNSSVSLPCDVHAHPN-PEVTWYK----DSQALSLGEEV--FLLPGTH-------- 1709
Query: 126 YSLNDATITLHNIGFSDSGKYICKAVTFPLGNAQSSTTVTVLVEPTV-SLIKGPDS--LI 182
T+ L SDSG Y C+A+ G Q ++VLV P +GP L+
Sbjct: 1710 ------TLQLGRARLSDSGMYTCEALN-AAGRDQKLVQLSVLVPPAFRQAPRGPQDAVLV 1762
Query: 183 DGGNETVAAICIAATGKPVAHIDWEGD 209
G++ V + A +P + W D
Sbjct: 1763 RVGDKAVLSCETDALPEPT--VTWYKD 1787
>gi|32699028 V-set and immunoglobulin domain containing 1 [Homo
sapiens]
Length = 387
Score = 54.3 bits (129), Expect = 3e-07
Identities = 49/171 (28%), Positives = 82/171 (47%), Gaps = 17/171 (9%)
Query: 47 LLFSRLCGALAGPIIVEPH--VTAVWGKNVSLKCLIEVNETITQ---ISWEKIHGKSSQT 101
L+ S L G ++ + P V G NV+L C+ + I W H K +
Sbjct: 10 LILSCLAGQVSVVQVTIPDGFVNVTVGSNVTLICIYTTTVASREQLSIQWSFFHKKEMEP 69
Query: 102 VAVHHPQYGFSVQ-GEYQGRVLFKNYSLNDATITLHNIGFSDSGKYICKAVTFP--LGNA 158
++++ Q G +V G+++ R+ N N A+IT+ ++ +DSG YIC P LG
Sbjct: 70 ISIYFSQGGQAVAIGQFKDRITGSNDPGN-ASITISHMQPADSGIYICDVNNPPDFLGQN 128
Query: 159 QSSTTVTVLVEPTVSL--IKG-PDSLIDGGNETVAAICIAATGKPVAHIDW 206
Q V+VLV+P+ L ++G P++ T++ C++A G P W
Sbjct: 129 QGILNVSVLVKPSKPLCSVQGRPET-----GHTISLSCLSALGTPSPVYYW 174
>gi|11225258 myelin associated glycoprotein isoform a precursor
[Homo sapiens]
Length = 626
Score = 53.9 bits (128), Expect = 4e-07
Identities = 66/271 (24%), Positives = 104/271 (38%), Gaps = 31/271 (11%)
Query: 113 VQGEYQGRV-LFKNYSLNDATITLHNIGFSDSGKYICKAVTFPLGNAQSSTTVTVLVEPT 171
V +QGR L + L + T+ L N+ GKY + S + + T
Sbjct: 81 VHESFQGRSRLLGDLGLRNCTLLLSNVSPELGGKYYFRGDLGGYNQYTFSEHSVLDIVNT 140
Query: 172 VSLIKGPDSLIDGGNETVAAICIAATGKPVAH--IDWEGDLGEMESTTTSFPNE---TAT 226
+++ P+ + G E V C+ P + W G G E E T
Sbjct: 141 PNIVVPPE--VVAGTE-VEVSCMVPDNCPELRPELSWLGHEGLGEPAVLGRLREDEGTWV 197
Query: 227 IISQYKLFPTRFARGRRITCVVKHPALEKDIRYSFILDIQYAPEV-----SVTGYDGNWF 281
+S PTR A G R+ C P +D++Y P + SV +G+
Sbjct: 198 QVSLLHFVPTREANGHRLGCQASFPNTTLQFEGYASMDVKYPPVIVEMNSSVEAIEGS-- 255
Query: 282 VGRKGVNLKCNADANPPPFKSVWSRLDGQWPDGLL----ASDNTLHFVHPLTFNYSGVYI 337
V+L C AD+NPPP + W R DG + +++ L + +T GVY
Sbjct: 256 ----HVSLLCGADSNPPPLLT-WMR------DGTVLREAVAESLLLELEEVTPAEDGVYA 304
Query: 338 CKVTNSLGQRSDQKVIYISDPPTTTTLQPTI 368
C N+ GQ + + + P T+ T+
Sbjct: 305 CLAENAYGQDNRTVGLSVMYAPWKPTVNGTM 335
>gi|18104957 myelin associated glycoprotein isoform b precursor
[Homo sapiens]
Length = 582
Score = 53.9 bits (128), Expect = 4e-07
Identities = 66/271 (24%), Positives = 104/271 (38%), Gaps = 31/271 (11%)
Query: 113 VQGEYQGRV-LFKNYSLNDATITLHNIGFSDSGKYICKAVTFPLGNAQSSTTVTVLVEPT 171
V +QGR L + L + T+ L N+ GKY + S + + T
Sbjct: 81 VHESFQGRSRLLGDLGLRNCTLLLSNVSPELGGKYYFRGDLGGYNQYTFSEHSVLDIVNT 140
Query: 172 VSLIKGPDSLIDGGNETVAAICIAATGKPVAH--IDWEGDLGEMESTTTSFPNE---TAT 226
+++ P+ + G E V C+ P + W G G E E T
Sbjct: 141 PNIVVPPE--VVAGTE-VEVSCMVPDNCPELRPELSWLGHEGLGEPAVLGRLREDEGTWV 197
Query: 227 IISQYKLFPTRFARGRRITCVVKHPALEKDIRYSFILDIQYAPEV-----SVTGYDGNWF 281
+S PTR A G R+ C P +D++Y P + SV +G+
Sbjct: 198 QVSLLHFVPTREANGHRLGCQASFPNTTLQFEGYASMDVKYPPVIVEMNSSVEAIEGS-- 255
Query: 282 VGRKGVNLKCNADANPPPFKSVWSRLDGQWPDGLL----ASDNTLHFVHPLTFNYSGVYI 337
V+L C AD+NPPP + W R DG + +++ L + +T GVY
Sbjct: 256 ----HVSLLCGADSNPPPLLT-WMR------DGTVLREAVAESLLLELEEVTPAEDGVYA 304
Query: 338 CKVTNSLGQRSDQKVIYISDPPTTTTLQPTI 368
C N+ GQ + + + P T+ T+
Sbjct: 305 CLAENAYGQDNRTVGLSVMYAPWKPTVNGTM 335
>gi|26006461 kin of IRRE like 3 isoform 1 [Homo sapiens]
Length = 778
Score = 52.8 bits (125), Expect = 8e-07
Identities = 86/341 (25%), Positives = 125/341 (36%), Gaps = 58/341 (17%)
Query: 151 VTFPLGNAQSSTTVTVLVEPTVSLIKGPDSL-IDGGNETVAAICIAATGKPVAHIDW--- 206
VT LG+ S TV V P ++ P SL +D G++ + + A TG P I W
Sbjct: 316 VTNALGSTNLSRTVDVYFGPRMTT--EPQSLLVDLGSDAIFSC--AWTGNPSLTIVWMKR 371
Query: 207 -EGDLGEMESTTT--SFPNETATIISQYKLFPTRFARGRRITCVVKHPALEKDIRYSFIL 263
G + E T T S E A + P A R +T V P + + L
Sbjct: 372 GSGVVLSNEKTLTLKSVRQEDAGKYVCRAVVPRVGAGEREVTLTVNGPPIISSTQTQHAL 431
Query: 264 DIQYAPEVSVTGYDGNWFVGRKGVNLKCNADANPPPFKSVWSRLDGQWPDGLLASDNTLH 323
G KG +KC + PPP + WS W + +L S +
Sbjct: 432 H------------------GEKG-QIKCFIRSTPPPDRIAWS-----WKENVLESGTSGR 467
Query: 324 FVHPLTFNYSGVYICKVTNSLGQRSDQKVIYISDPPTTTTLQPTIQWHPSTADIEDLATE 383
+ GV I +T S R+D + IY W+ +D E + +
Sbjct: 468 YTVETISTEEGV-ISTLTISNIVRADFQTIY-----------NCTAWNSFGSDTEIIRLK 515
Query: 384 PKKLPFPLSTLATIKDDTIATIIASVVG-GALFIVLVSVLAGIFCYRRRRTFRGDYFAKN 442
+ + +A II VG G F+VL++ + C R +R +G AKN
Sbjct: 516 EQGSEMKSGAGLEAESVPMAVIIGVAVGAGVAFLVLMATIVAFCCARSQRNLKGVVSAKN 575
Query: 443 YIPPSDMQKE----------SQIDVLQQDELDSYPDSVKKE 473
I + KE S I L D + DSV K+
Sbjct: 576 DIRVEIVHKEPASGREGEEHSTIKQLMMDRGEFQQDSVLKQ 616
Score = 52.4 bits (124), Expect = 1e-06
Identities = 55/226 (24%), Positives = 95/226 (42%), Gaps = 11/226 (4%)
Query: 142 DSGKYICKAVTFPLGNAQSSTTVTVLVEPTVSLIKGPDSLIDGGNETVAAICIAATGKPV 201
D Y C+A+ + + + +TVLV P +I G + + + C A KP
Sbjct: 121 DDAVYECQAIQAAIRSRPAR--LTVLVPPDDPVILGGPVISLRAGDPLNLTCHADNAKPA 178
Query: 202 AHIDW--EGDL--GEMESTTTSFPNETATIISQYKLFPTRFARGRRITCVVKHPALEKDI 257
A I W +G++ G S T + +I+S + P G+ I C + A+
Sbjct: 179 ASIIWLRKGEVINGATYSKTLLRDGKRESIVSTLFISPGDVENGQSIVCRATNKAIPGGK 238
Query: 258 RYSFILDIQYAPEVSVTGYDGNWFVGRKGVNLKCNADANPPPFKSVWSRLDGQWPDGLLA 317
S +DIQ+ P V+++ + + V C+A ANP + W++ + A
Sbjct: 239 ETSVTIDIQHPPLVNLS-VEPQPVLEDNVVTFHCSAKANPAVTQYRWAKRGQIIKE---A 294
Query: 318 SDNTLHFVHPLTFNYSGVYICKVTNSLGQRSDQKVIYISDPPTTTT 363
S T+ +S C+VTN+LG + + + + P TT
Sbjct: 295 SGEVYRTTVDYTY-FSEPVSCEVTNALGSTNLSRTVDVYFGPRMTT 339
Score = 41.6 bits (96), Expect = 0.002
Identities = 26/90 (28%), Positives = 42/90 (46%), Gaps = 3/90 (3%)
Query: 129 NDATITLHNIGFSDSGKYICKAVTFPLGNAQSSTTVTVLVEPTVSLIKGPDSLIDGGNET 188
N+ T+TL ++ D+GKY+C+AV +G + T+TV P +S + +L E
Sbjct: 379 NEKTLTLKSVRQEDAGKYVCRAVVPRVGAGEREVTLTVNGPPIISSTQTQHAL---HGEK 435
Query: 189 VAAICIAATGKPVAHIDWEGDLGEMESTTT 218
C + P I W +ES T+
Sbjct: 436 GQIKCFIRSTPPPDRIAWSWKENVLESGTS 465
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.136 0.414
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,869,702
Number of Sequences: 37866
Number of extensions: 1103797
Number of successful extensions: 4784
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 58
Number of HSP's successfully gapped in prelim test: 234
Number of HSP's that attempted gapping in prelim test: 3845
Number of HSP's gapped (non-prelim): 969
length of query: 549
length of database: 18,247,518
effective HSP length: 107
effective length of query: 442
effective length of database: 14,195,856
effective search space: 6274568352
effective search space used: 6274568352
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.