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Search of human proteins with 21361429
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|21361429 V-set and immunoglobulin domain containing 2 [Homo
sapiens]
(327 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|21361429 V-set and immunoglobulin domain containing 2 [Homo s... 657 0.0
gi|32699028 V-set and immunoglobulin domain containing 1 [Homo s... 154 1e-37
gi|62865876 immunoglobulin superfamily, member 11 isoform b [Hom... 145 5e-35
gi|62865874 immunoglobulin superfamily, member 11 isoform a [Hom... 144 1e-34
gi|4503173 coxsackie virus and adenovirus receptor precursor [Ho... 119 3e-27
gi|5031561 transmembrane glycoprotein A33 precursor [Homo sapiens] 117 1e-26
gi|148664205 endothelial cell adhesion molecule [Homo sapiens] 115 5e-26
gi|13376115 adipocyte-specific adhesion molecule [Homo sapiens] 111 8e-25
gi|21361905 junctional adhesion molecule 3 precursor [Homo sapiens] 88 1e-17
gi|8393638 F11 receptor precursor [Homo sapiens] 81 1e-15
gi|61966777 V-set and immunoglobulin domain containing 8 [Homo s... 75 8e-14
gi|193083163 roundabout, axon guidance receptor, homolog 2 isofo... 70 3e-12
gi|61888896 roundabout, axon guidance receptor, homolog 2 isofor... 70 3e-12
gi|121674801 hepatocyte cell adhesion molecule [Homo sapiens] 69 4e-12
gi|10864029 junctional adhesion molecule 2 precursor [Homo sapiens] 65 8e-11
gi|28373126 contactin 4 isoform c precursor [Homo sapiens] 64 1e-10
gi|28373122 contactin 4 isoform a precursor [Homo sapiens] 64 1e-10
gi|98986445 carcinoembryonic antigen-related cell adhesion molec... 63 4e-10
gi|13376852 CD276 antigen isoform b [Homo sapiens] 62 7e-10
gi|118572606 hemicentin 1 [Homo sapiens] 61 2e-09
gi|239755187 PREDICTED: similar to hemicentin 2 [Homo sapiens] 60 2e-09
gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens] 60 2e-09
gi|5901908 butyrophilin, subfamily 3, member A3 isoform a [Homo ... 60 2e-09
gi|67188443 CD276 antigen isoform a [Homo sapiens] 60 3e-09
gi|239743951 PREDICTED: hypothetical protein XP_002342997 [Homo ... 60 3e-09
gi|40255013 carcinoembryonic antigen-related cell adhesion molec... 59 5e-09
gi|19923629 Fc receptor-like 2 precursor [Homo sapiens] 57 2e-08
gi|109150416 peroxidasin [Homo sapiens] 57 2e-08
gi|19882241 immunoglobulin superfamily, DCC subclass, member 4 [... 57 2e-08
gi|38490688 immunoglobulin superfamily, member 10 [Homo sapiens] 57 3e-08
>gi|21361429 V-set and immunoglobulin domain containing 2 [Homo
sapiens]
Length = 327
Score = 657 bits (1696), Expect = 0.0
Identities = 327/327 (100%), Positives = 327/327 (100%)
Query: 1 MAELPGPFLCGALLGFLCLSGLAVEVKVPTEPLSTPLGKTAELTCTYSTSVGDSFALEWS 60
MAELPGPFLCGALLGFLCLSGLAVEVKVPTEPLSTPLGKTAELTCTYSTSVGDSFALEWS
Sbjct: 1 MAELPGPFLCGALLGFLCLSGLAVEVKVPTEPLSTPLGKTAELTCTYSTSVGDSFALEWS 60
Query: 61 FVQPGKPISESHPILYFTNGHLYPTGSKSKRVSLLQNPPTVGVATLKLTDVHPSDTGTYL 120
FVQPGKPISESHPILYFTNGHLYPTGSKSKRVSLLQNPPTVGVATLKLTDVHPSDTGTYL
Sbjct: 61 FVQPGKPISESHPILYFTNGHLYPTGSKSKRVSLLQNPPTVGVATLKLTDVHPSDTGTYL 120
Query: 121 CQVNNPPDFYTNGLGLINLTVLVPPSNPLCSQSGQTSVGGSTALRCSSSEGAPKPVYNWV 180
CQVNNPPDFYTNGLGLINLTVLVPPSNPLCSQSGQTSVGGSTALRCSSSEGAPKPVYNWV
Sbjct: 121 CQVNNPPDFYTNGLGLINLTVLVPPSNPLCSQSGQTSVGGSTALRCSSSEGAPKPVYNWV 180
Query: 181 RLGTFPTPSPGSMVQDEVSGQLILTNLSLTSSGTYRCVATNQMGSASCELTLSVTEPSQG 240
RLGTFPTPSPGSMVQDEVSGQLILTNLSLTSSGTYRCVATNQMGSASCELTLSVTEPSQG
Sbjct: 181 RLGTFPTPSPGSMVQDEVSGQLILTNLSLTSSGTYRCVATNQMGSASCELTLSVTEPSQG 240
Query: 241 RVAGALIGVLLGVLLLSVAAFCLVRFQKERGKKPKETYGGSDLREDAIAPGISEHTCMRA 300
RVAGALIGVLLGVLLLSVAAFCLVRFQKERGKKPKETYGGSDLREDAIAPGISEHTCMRA
Sbjct: 241 RVAGALIGVLLGVLLLSVAAFCLVRFQKERGKKPKETYGGSDLREDAIAPGISEHTCMRA 300
Query: 301 DSSKGFLERPSSASTVTTTKSKLPMVV 327
DSSKGFLERPSSASTVTTTKSKLPMVV
Sbjct: 301 DSSKGFLERPSSASTVTTTKSKLPMVV 327
>gi|32699028 V-set and immunoglobulin domain containing 1 [Homo
sapiens]
Length = 387
Score = 154 bits (389), Expect = 1e-37
Identities = 100/308 (32%), Positives = 163/308 (52%), Gaps = 21/308 (6%)
Query: 16 FLCLSGLA-----VEVKVPTEPLSTPLGKTAELTCTYSTSVG--DSFALEWSFVQPGKPI 68
FL LS LA V+V +P ++ +G L C Y+T+V + +++WSF
Sbjct: 9 FLILSCLAGQVSVVQVTIPDGFVNVTVGSNVTLICIYTTTVASREQLSIQWSFFHK---- 64
Query: 69 SESHPI-LYFTNG-HLYPTGSKSKRVSLLQNPPTVGVATLKLTDVHPSDTGTYLCQVNNP 126
E PI +YF+ G G R++ +P G A++ ++ + P+D+G Y+C VNNP
Sbjct: 65 KEMEPISIYFSQGGQAVAIGQFKDRITGSNDP---GNASITISHMQPADSGIYICDVNNP 121
Query: 127 PDFYTNGLGLINLTVLVPPSNPLCSQSGQTSVGGSTALRCSSSEGAPKPVYNWVRL-GTF 185
PDF G++N++VLV PS PLCS G+ G + +L C S+ G P PVY W +L G
Sbjct: 122 PDFLGQNQGILNVSVLVKPSKPLCSVQGRPETGHTISLSCLSALGTPSPVYYWHKLEGRD 181
Query: 186 PTPSPGSMVQDEVSGQLILTNLSLTSSGTYRCVATNQMGSASCELTLSVTEPSQGRVAGA 245
P + + +G L++ NL+ G Y+C A N++G++SCE+ L+ + P G + GA
Sbjct: 182 IVPVKENF--NPTTGILVIGNLTNFEQGYYQCTAINRLGNSSCEIDLTSSHPEVGIIVGA 239
Query: 246 LIGVLLGVLLLSVAAFCLVRFQKERGKKPKETYGGSDLRE-DAIAPGISEHTCMRADSSK 304
LIG L+G ++ ++ C R + + K + + ++L I P R D+++
Sbjct: 240 LIGSLVGAAII-ISVVCFARNKAKAKAKERNSKTIAELEPMTKINPRGESEAMPREDATQ 298
Query: 305 GFLERPSS 312
+ PSS
Sbjct: 299 LEVTLPSS 306
>gi|62865876 immunoglobulin superfamily, member 11 isoform b [Homo
sapiens]
Length = 431
Score = 145 bits (366), Expect = 5e-35
Identities = 103/318 (32%), Positives = 155/318 (48%), Gaps = 20/318 (6%)
Query: 12 ALLGFLCLSGLAVEVKVPTEPLSTPL--GKTAELTCTYSTSVG-DSFALEWSFVQPGKPI 68
A L L L G+A ++V P S + G+ A L CT++TS + + W V P
Sbjct: 9 APLLLLSLHGVAASLEVSESPGSIQVARGQPAVLPCTFTTSAALINLNVIW-MVTPLSNA 67
Query: 69 SESHPILYFTNGHLYPTGSKSK-RVSLLQNPPTVGVATLKLTDVHPSDTGTYLCQVNNPP 127
++ ++ + G ++ + RV P V+ + + SDTGTY C VNN P
Sbjct: 68 NQPEQVILYQGGQMFDGAPRFHGRVGFTGTMPATNVSIF-INNTQLSDTGTYQCLVNNLP 126
Query: 128 DFYTNGLGLINLTVLVPPSNPLCSQSGQTSVGGSTALRCSSSEGAPKPVYNWVRLGTFPT 187
D +G+ LTVLVPPS P C G +G L CSS EG P+P Y W +L
Sbjct: 127 DIGGRNIGVTGLTVLVPPSAPHCQIQGSQDIGSDVILLCSSEEGIPRPTYLWEKLDN-TL 185
Query: 188 PSPGSMVQDEVSGQLILTNLSLTSSGTYRCVATNQMGSASCELTLSVTEPSQ---GRVAG 244
P + QD+V G + + N+S SSG Y+CVA+N +G+++C L L V P G +AG
Sbjct: 186 KLPPTATQDQVQGTVTIRNISALSSGLYQCVASNAIGTSTCLLDLQVISPQPRNIGLIAG 245
Query: 245 ALIGVLLGVLLLSVAAFCLVRFQ-KERGKKPKETYGGSDLREDAIAPGISEHTCMRADSS 303
A IG +++ +A F + + K+ +E +++RED + P + S+
Sbjct: 246 A-IGTGAVIIIFCIALILGAFFYWRSKNKEEEEEEIPNEIREDDLPP--------KCSSA 296
Query: 304 KGFLERPSSASTVTTTKS 321
K F SS+ T T S
Sbjct: 297 KAFHTEISSSDNNTLTSS 314
>gi|62865874 immunoglobulin superfamily, member 11 isoform a [Homo
sapiens]
Length = 430
Score = 144 bits (363), Expect = 1e-34
Identities = 103/319 (32%), Positives = 156/319 (48%), Gaps = 22/319 (6%)
Query: 13 LLGFLCLS--GLAVEVKVPTEPLSTPL--GKTAELTCTYSTSVG-DSFALEWSFVQPGKP 67
LL + C S G+A ++V P S + G+ A L CT++TS + + W V P
Sbjct: 7 LLWWNCFSRTGVAASLEVSESPGSIQVARGQPAVLPCTFTTSAALINLNVIW-MVTPLSN 65
Query: 68 ISESHPILYFTNGHLYPTGSKSK-RVSLLQNPPTVGVATLKLTDVHPSDTGTYLCQVNNP 126
++ ++ + G ++ + RV P V+ + + SDTGTY C VNN
Sbjct: 66 ANQPEQVILYQGGQMFDGAPRFHGRVGFTGTMPATNVSIF-INNTQLSDTGTYQCLVNNL 124
Query: 127 PDFYTNGLGLINLTVLVPPSNPLCSQSGQTSVGGSTALRCSSSEGAPKPVYNWVRLGTFP 186
PD +G+ LTVLVPPS P C G +G L CSS EG P+P Y W +L
Sbjct: 125 PDIGGRNIGVTGLTVLVPPSAPHCQIQGSQDIGSDVILLCSSEEGIPRPTYLWEKLDN-T 183
Query: 187 TPSPGSMVQDEVSGQLILTNLSLTSSGTYRCVATNQMGSASCELTLSVTEPSQ---GRVA 243
P + QD+V G + + N+S SSG Y+CVA+N +G+++C L L V P G +A
Sbjct: 184 LKLPPTATQDQVQGTVTIRNISALSSGLYQCVASNAIGTSTCLLDLQVISPQPRNIGLIA 243
Query: 244 GALIGVLLGVLLLSVAAFCLVRFQ-KERGKKPKETYGGSDLREDAIAPGISEHTCMRADS 302
GA IG +++ +A F + + K+ +E +++RED + P + S
Sbjct: 244 GA-IGTGAVIIIFCIALILGAFFYWRSKNKEEEEEEIPNEIREDDLPP--------KCSS 294
Query: 303 SKGFLERPSSASTVTTTKS 321
+K F SS+ T T S
Sbjct: 295 AKAFHTEISSSDNNTLTSS 313
>gi|4503173 coxsackie virus and adenovirus receptor precursor [Homo
sapiens]
Length = 365
Score = 119 bits (299), Expect = 3e-27
Identities = 89/289 (30%), Positives = 132/289 (45%), Gaps = 19/289 (6%)
Query: 13 LLGFLCLSGL-----AVEVKVPTEPLSTPLGKTAELTCTYSTSVGDSFAL--EWSFVQPG 65
LL F+ L G+ ++ + P E + G+TA L C ++ S D L EW + P
Sbjct: 4 LLCFVLLCGVVDFARSLSITTPEEMIEKAKGETAYLPCKFTLSPEDQGPLDIEW-LISPA 62
Query: 66 KPISESHPILYFTNGHLYPT--GSKSKRVSLLQNPPTVGVATLKLTDVHPSDTGTYLCQV 123
I+ ++ +Y RV N G A++ +T++ SD GTY C+V
Sbjct: 63 DNQKVDQVIILYSGDKIYDDYYPDLKGRVHFTSNDLKSGDASINVTNLQLSDIGTYQCKV 122
Query: 124 NNPPDFYTNGLGLINLTVLVPPSNPLCSQSGQTSVGGSTALRCSSSEGAPKPVYNWVRLG 183
P I+L VLV PS C G +G ++C EG+ Y W +L
Sbjct: 123 KKAPGVANKK---IHLVVLVKPSGARCYVDGSEEIGSDFKIKCEPKEGSLPLQYEWQKLS 179
Query: 184 TFPTPSPGSMVQDEVSGQLILTNLSLTSSGTYRCVATNQMGSASCELTLSVTEPSQ--GR 241
P S + + S + + N S SGTY C N++GS C L L+V PS G
Sbjct: 180 D-SQKMPTSWLAEMTSSVISVKNASSEYSGTYSCTVRNRVGSDQCLLRLNVVPPSNKAGL 238
Query: 242 VAGALIGVLLGVLLLSVAAFCLVRFQKERGKKPKETYGGSDLREDAIAP 290
+AGA+IG LL + L+ + FC + ++E K KE + D+RED P
Sbjct: 239 IAGAIIGTLLALALIGLIIFCCRKKRREE-KYEKEVH--HDIREDVPPP 284
>gi|5031561 transmembrane glycoprotein A33 precursor [Homo sapiens]
Length = 319
Score = 117 bits (294), Expect = 1e-26
Identities = 79/260 (30%), Positives = 122/260 (46%), Gaps = 14/260 (5%)
Query: 23 AVEVKVPTEPLSTPLGKTAELTCTYSTSVGDSFALEWSFVQPGKPI---SESHPILYFTN 79
A+ V+ P + L GK+ L CTY TS L +Q K + +E I F+N
Sbjct: 21 AISVETPQDVLRASQGKSVTLPCTYHTSTSSREGL----IQWDKLLLTHTERVVIWPFSN 76
Query: 80 GHLYPTGSKSKRVSLLQNPPTVGVATLKLTDVHPSDTGTYLCQVNNPPDFYTNGLGLINL 139
+ RVS+ N A++ + + +D GTY C V+ D N + L
Sbjct: 77 KNYIHGELYKNRVSISNNAEQSD-ASITIDQLTMADNGTYECSVSLMSDLEGNTKSRVRL 135
Query: 140 TVLVPPSNPLCSQSGQTSVGGSTALRCSSSEGAPKPVYNWVRLGTFPTPSPGSMVQDEVS 199
VLVPPS P C G+T +G + L C S EG+P P Y+W R P + S
Sbjct: 136 LVLVPPSKPECGIEGETIIGNNIQLTCQSKEGSPTPQYSWKRYNILNQEQP---LAQPAS 192
Query: 200 GQLI-LTNLSLTSSGTYRCVATNQMGSASCELTLSVTEPSQ--GRVAGALIGVLLGVLLL 256
GQ + L N+S +SG Y C ++N+ G+ C +T++V PS G +GV+ ++++
Sbjct: 193 GQPVSLKNISTDTSGYYICTSSNEEGTQFCNITVAVRSPSMNVALYVGIAVGVVAALIII 252
Query: 257 SVAAFCLVRFQKERGKKPKE 276
+ +C K+ + KE
Sbjct: 253 GIIIYCCCCRGKDDNTEDKE 272
>gi|148664205 endothelial cell adhesion molecule [Homo sapiens]
Length = 390
Score = 115 bits (288), Expect = 5e-26
Identities = 107/339 (31%), Positives = 157/339 (46%), Gaps = 33/339 (9%)
Query: 1 MAELPGPFLCGAL-LGFLCLSGLA------VEVKVPTEPLSTPLGKTAELTCTYST--SV 51
M LPGP + L FL LS LA +++ +P L G L Y+ V
Sbjct: 1 MISLPGPLVTNLLRFLFLGLSALAPPSRAQLQLHLPANRLQAVEGGEVVLPAWYTLHGEV 60
Query: 52 GDSFALEWSFVQPG-KPISESHPILYFTNGHLYPTGSKSKRVSLLQNPPTVGVATLKLTD 110
S E FV K + +L + NG + VSL+ + P+ ++ L+L
Sbjct: 61 SSSQPWEVPFVMWFFKQKEKEDQVLSYING----VTTSKPGVSLVYSMPSRNLS-LRLEG 115
Query: 111 VHPSDTGTYLCQVN---NPPDFYTNGLGLINLTVLVPPSNPLCSQSGQTSVGGSTALRCS 167
+ D+G Y C VN + + + L VLVPP+ P C G VG + L C
Sbjct: 116 LQEKDSGPYSCSVNVQDKQGKSRGHSIKTLELNVLVPPAPPSCRLQGVPHVGANVTLSCQ 175
Query: 168 SSEGAPKPVYNWVR-LGTFPTPSPGSMVQDEVSGQLILTNLSLTSSGTYRCVATNQMGSA 226
S P Y W R L +F T ++ D + G L LTNLS + +G Y C A N++G+A
Sbjct: 176 SPRSKPAVQYQWDRQLPSFQTFFAPAL--DVIRGSLSLTNLSSSMAGVYVCKAHNEVGTA 233
Query: 227 SCELTLSV-TEPSQGRVAGALIGVLLGVLLLSVAAFCLVRFQKERGKKPKETYGGSDLRE 285
C +TL V T P VAGA++G L+G+ LL+ LV RGK +E +D++E
Sbjct: 234 QCNVTLEVSTGPGAAVVAGAVVGTLVGLGLLA----GLVLLYHRRGKALEEP--ANDIKE 287
Query: 286 DAIAPGISEHTCMRADSSKGFLERPSSASTVTTTKSKLP 324
DAIAP + S + + + S+VT+ ++ P
Sbjct: 288 DAIAP-----RTLPWPKSSDTISKNGTLSSVTSARALRP 321
>gi|13376115 adipocyte-specific adhesion molecule [Homo sapiens]
Length = 373
Score = 111 bits (278), Expect = 8e-25
Identities = 97/322 (30%), Positives = 150/322 (46%), Gaps = 31/322 (9%)
Query: 17 LCLSGLAVEVKVPTEPLSTPLGKTAE----LTCTYSTSVG--DSFALEWSFVQPGKPISE 70
L L L V V T T + + AE L C + + D+ +EW
Sbjct: 3 LLLLLLLVSYYVGTLGTHTEIKRVAEEKVTLPCHHQLGLPEKDTLDIEWLLTDNE---GN 59
Query: 71 SHPILYFTNGHLYP--TGSKSKRVSLLQNPPTVGVATLKLTDVHPSDTGTYLCQVNNPPD 128
++ +++ H+Y T + RV+ N G A+L++ + PSD G Y C+V N
Sbjct: 60 QKVVITYSSRHVYNNLTEEQKGRVAFASNF-LAGDASLQIEPLKPSDEGRYTCKVKNSGR 118
Query: 129 FYTNGLGLINLTVLVPPSNPLCSQSGQTSVGGSTALRCSSSEGAPKPVYNWVRL----GT 184
+ + + L VLV PS P C G+ + G L+C SS G VY W R+ G
Sbjct: 119 YVWSH---VILKVLVRPSKPKCELEGELTEGSDLTLQCESSSGTEPIVYYWQRIREKEGE 175
Query: 185 FPTPSPGSMVQDEVSGQLILTNLSLTSSGTYRCVATNQMGSASCELTLSVT-EPSQGRVA 243
P S + G+++L NL+++ SG Y+C A N+ G SC + ++V S G VA
Sbjct: 176 DERLPPKSRIDYNHPGRVLLQNLTMSYSGLYQCTAGNEAGKESCVVRVTVQYVQSIGMVA 235
Query: 244 GALIGVLLGVLLLSVAAFCLVRFQKERGKKPKETY----GGSDLREDAIAPGISEHTCMR 299
GA+ G++ G LL+ + + L+R +K KE Y +++REDA AP +
Sbjct: 236 GAVTGIVAGALLIFLLVWLLIR------RKDKERYEEEERPNEIREDAEAPK-ARLVKPS 288
Query: 300 ADSSKGFLERPSSASTVTTTKS 321
+ SS R S+ST +T S
Sbjct: 289 SSSSGSRSSRSGSSSTRSTANS 310
>gi|21361905 junctional adhesion molecule 3 precursor [Homo sapiens]
Length = 355
Score = 87.8 bits (216), Expect = 1e-17
Identities = 80/273 (29%), Positives = 116/273 (42%), Gaps = 26/273 (9%)
Query: 2 AELPGPFLCGALLGFLCLSGLAVEVKVPTEPLSTPLGKTAELTCTYSTSVGDSFALEWSF 61
A LP FL G CL G AV +K ++ EL+C + S +EW
Sbjct: 58 ARLPDFFLLLLFRG--CLIG-AVNLKSSNRTPVVQEFESVELSCIITDSQTSDPRIEWKK 114
Query: 62 VQPGKPISESHPILYFTNGHLYPTGSKSKRVSLLQNPPTVGVATLKLTDVHPSDTGTYLC 121
+Q E ++F N G + R +L G +LK+ +V D+ Y C
Sbjct: 115 IQ-----DEQTTYVFFDNKI---QGDLAGRAEIL------GKTSLKIWNVTRRDSALYRC 160
Query: 122 QVNNPPDFYTNGLGLINLTVLVPPSNPLCSQSGQTSVGGSTALRCSSSEGAPKPVYNWVR 181
+V D +I LTV V P P+C VG L C SEG P+P Y+W R
Sbjct: 161 EVVARNDRKEIDEIVIELTVQVKPVTPVCRVPKAVPVGKMATLHCQESEGHPRPHYSWYR 220
Query: 182 LGT-FPTPS-------PGSMVQDEVSGQLILTNLSLTSSGTYRCVATNQMGSASC-ELTL 232
PT S S + +G L+ T + SG Y C+A+N GSA C E +
Sbjct: 221 NDVPLPTDSRANPRFRNSSFHLNSETGTLVFTAVHKDDSGQYYCIASNDAGSARCEEQEM 280
Query: 233 SVTEPSQGRVAGALIGVLLGVLLLSVAAFCLVR 265
V + + G + G ++ VL + L+++ C R
Sbjct: 281 EVYDLNIGGIIGGVLVVLAVLALITLGICCAYR 313
>gi|8393638 F11 receptor precursor [Homo sapiens]
Length = 299
Score = 81.3 bits (199), Expect = 1e-15
Identities = 76/277 (27%), Positives = 118/277 (42%), Gaps = 38/277 (13%)
Query: 9 LCGALLGFLCLSGLAVEVKVPTEPLSTPLGKTAELTCTYSTSVGDSFALEWSFVQPGKPI 68
LC LG + + EV++P +L+C YS S +EW F Q
Sbjct: 21 LCSLALGSVTVHSSEPEVRIPEN-------NPVKLSCAYSGF--SSPRVEWKFDQ----- 66
Query: 69 SESHPILYFTNGHLYPTGSKSKRVSLLQNPPTVGVATLKLTDVHPSDTGTYLCQVNNPPD 128
++ ++ + N T S RV+ L PT + V DTGTY C V+
Sbjct: 67 GDTTRLVCYNNKI---TASYEDRVTFL---PT----GITFKSVTREDTGTYTCMVSEEGG 116
Query: 129 FYTNGLGLINLTVLVPPSNPLCSQSGQTSVGGSTALRCSSSEGAPKPVYNWVRLGTFPTP 188
+ G + L VLVPPS P + ++G L CS +G+P Y W + G
Sbjct: 117 -NSYGEVKVKLIVLVPPSKPTVNIPSSATIGNRAVLTCSEQDGSPPSEYTWFKDGIVMPT 175
Query: 189 SP--------GSMVQDEVSGQLILTNLSLTSSGTYRCVATNQMGS--ASCELTLSVTEPS 238
+P S V + +G+L+ LS + +G Y C A N G+ S + + E +
Sbjct: 176 NPKSTRAFSNSSYVLNPTTGELVFDPLSASDTGEYSCEARNGYGTPMTSNAVRMEAVERN 235
Query: 239 QGRVAGALIG--VLLGVLLLSVAAFCLVRFQKERGKK 273
G + A++ +LLG+L+ + F R +R KK
Sbjct: 236 VGVIVAAVLVTLILLGILVFGI-WFAYSRGHFDRTKK 271
>gi|61966777 V-set and immunoglobulin domain containing 8 [Homo
sapiens]
Length = 414
Score = 75.1 bits (183), Expect = 8e-14
Identities = 62/244 (25%), Positives = 101/244 (41%), Gaps = 49/244 (20%)
Query: 90 KRVSLLQNPPTVGVATLKLTDVHPSDTGTYLCQVNNPPDFYTNGLGLINLTVLVPPSNPL 149
+RV + P+ A++ L ++ SDT TY C+V T + +TV P+ P+
Sbjct: 95 QRVRFAASDPSQYDASINLMNLQVSDTATYECRVKKT----TMATRKVIVTVQARPAVPM 150
Query: 150 CSQSGQTSVGGSTALRCSSSEGAPKPVYNWVRLG---------------------TFPTP 188
C G + G L+C +S G+ Y W ++ ++
Sbjct: 151 CWTEGHMTYGNDVVLKCYASGGSQPLSYKWAKISGHHYPYRAGSYTSQHSYHSELSYQES 210
Query: 189 SPGSMVQDEVSGQLILTNLSLTSSGTYRCVATNQMGSASCELTLSVTEPSQGRVAGALIG 248
S+ Q +G L+L ++S G Y+C N +G + C + + V S R G +IG
Sbjct: 211 FHSSINQGLNNGDLVLKDISRADDGLYQCTVANNVGYSVCVVEVKV---SDSRRIGVIIG 267
Query: 249 VLLGVLL----LSVAAF----CLVRFQKERGKKPKETYG-------------GSDLREDA 287
++LG LL L+V + C G + YG S++REDA
Sbjct: 268 IVLGSLLALGCLAVGIWGLVCCCCGGSGAGGARGAFGYGNGGGVGGGACGDLASEIREDA 327
Query: 288 IAPG 291
+APG
Sbjct: 328 VAPG 331
>gi|193083163 roundabout, axon guidance receptor, homolog 2 isoform
ROBO2a [Homo sapiens]
Length = 1394
Score = 70.1 bits (170), Expect = 3e-12
Identities = 48/135 (35%), Positives = 70/135 (51%), Gaps = 7/135 (5%)
Query: 106 LKLTDVHPSDTGTYLCQVNNPPDFYTNGLGLINLTVLV--PPSNPLCSQSGQT-SVGGST 162
L +T++ SD G Y+CQ L VL PP L + QT +V G+
Sbjct: 392 LTITNIQRSDAGYYICQALTVAGSILAKAQLEVTDVLTDRPPPIILQGPANQTLAVDGTA 451
Query: 163 ALRCSSSEGAPKPVYNWVRLG-TFPTPSPGSMVQDEVSGQLILTNLSLTSSGTYRCVATN 221
L+C ++ G P PV +W++ G TFP P + +Q++ G L + NL ++ +GTY CVAT+
Sbjct: 452 LLKCKAT-GDPLPVISWLKEGFTFPGRDPRATIQEQ--GTLQIKNLRISDTGTYTCVATS 508
Query: 222 QMGSASCELTLSVTE 236
G S L VTE
Sbjct: 509 SSGETSWSAVLDVTE 523
Score = 47.8 bits (112), Expect = 1e-05
Identities = 37/138 (26%), Positives = 57/138 (41%), Gaps = 10/138 (7%)
Query: 105 TLKLTDVHPSDTGTYLCQVNNPPDFYTNGLGLINLTVLVPPSNPLCSQSGQTSVGGSTAL 164
TL++ +D GTY+C N LTV PP + + + G +
Sbjct: 293 TLRIKKTMSTDEGTYMCIAENRVGKMEASA---TLTVRAPPQFVVRPRDQIVAQGRTVTF 349
Query: 165 RCSSSEGAPKPVYNWVRLGT----FPTP--SPGSMVQDEVSGQLILTNLSLTSSGTYRCV 218
C + +G P+P W + G+ FP P S +G L +TN+ + +G Y C
Sbjct: 350 PCET-KGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYICQ 408
Query: 219 ATNQMGSASCELTLSVTE 236
A GS + L VT+
Sbjct: 409 ALTVAGSILAKAQLEVTD 426
Score = 36.6 bits (83), Expect = 0.031
Identities = 46/186 (24%), Positives = 72/186 (38%), Gaps = 22/186 (11%)
Query: 62 VQPGKP-ISESHPILYFTNGHLYPT--GSKSK-RVSLLQNPPTVGVATLKLTDVHPSDTG 117
V G+P I E P GH PT K K R+ + ++ L +++ SD G
Sbjct: 160 VAAGEPAILECQP----PRGHPEPTIYWKKDKVRIDDKEERISIRGGKLMISNTRKSDAG 215
Query: 118 TYLCQVNNPPDFYTNGLGLINL----TVLVPPSNPLCSQSGQTSVGGSTALRCSSSEGAP 173
Y C N + + + T L P N + + + RC +G P
Sbjct: 216 MYTCVGTNMVGERDSDPAELTVFERPTFLRRPINQVVLEEE------AVEFRCQV-QGDP 268
Query: 174 KPVYNWVRLGTFPTPSPGSMVQDEVSGQLILTNLSLTSSGTYRCVATNQMGSASCELTLS 233
+P W + P ++D+ + L + T GTY C+A N++G TL+
Sbjct: 269 QPTVRWKK-DDADLPRGRYDIKDDYT--LRIKKTMSTDEGTYMCIAENRVGKMEASATLT 325
Query: 234 VTEPSQ 239
V P Q
Sbjct: 326 VRAPPQ 331
Score = 30.4 bits (67), Expect = 2.2
Identities = 25/78 (32%), Positives = 30/78 (38%), Gaps = 9/78 (11%)
Query: 157 SVGGSTALRCSSSEGAPKPVYNWVRLGT---FPTPSPGSMVQDEVSGQLILTNL-----S 208
S G T L C + EG P P W + G P S SG L + S
Sbjct: 59 SKGEPTTLNCKA-EGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRRS 117
Query: 209 LTSSGTYRCVATNQMGSA 226
G+Y CVA N +G A
Sbjct: 118 KPDEGSYVCVARNYLGEA 135
>gi|61888896 roundabout, axon guidance receptor, homolog 2 isoform
ROBO2b [Homo sapiens]
Length = 1378
Score = 70.1 bits (170), Expect = 3e-12
Identities = 48/135 (35%), Positives = 70/135 (51%), Gaps = 7/135 (5%)
Query: 106 LKLTDVHPSDTGTYLCQVNNPPDFYTNGLGLINLTVLV--PPSNPLCSQSGQT-SVGGST 162
L +T++ SD G Y+CQ L VL PP L + QT +V G+
Sbjct: 376 LTITNIQRSDAGYYICQALTVAGSILAKAQLEVTDVLTDRPPPIILQGPANQTLAVDGTA 435
Query: 163 ALRCSSSEGAPKPVYNWVRLG-TFPTPSPGSMVQDEVSGQLILTNLSLTSSGTYRCVATN 221
L+C ++ G P PV +W++ G TFP P + +Q++ G L + NL ++ +GTY CVAT+
Sbjct: 436 LLKCKAT-GDPLPVISWLKEGFTFPGRDPRATIQEQ--GTLQIKNLRISDTGTYTCVATS 492
Query: 222 QMGSASCELTLSVTE 236
G S L VTE
Sbjct: 493 SSGETSWSAVLDVTE 507
Score = 47.8 bits (112), Expect = 1e-05
Identities = 37/138 (26%), Positives = 57/138 (41%), Gaps = 10/138 (7%)
Query: 105 TLKLTDVHPSDTGTYLCQVNNPPDFYTNGLGLINLTVLVPPSNPLCSQSGQTSVGGSTAL 164
TL++ +D GTY+C N LTV PP + + + G +
Sbjct: 277 TLRIKKTMSTDEGTYMCIAENRVGKMEASA---TLTVRAPPQFVVRPRDQIVAQGRTVTF 333
Query: 165 RCSSSEGAPKPVYNWVRLGT----FPTP--SPGSMVQDEVSGQLILTNLSLTSSGTYRCV 218
C + +G P+P W + G+ FP P S +G L +TN+ + +G Y C
Sbjct: 334 PCET-KGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYICQ 392
Query: 219 ATNQMGSASCELTLSVTE 236
A GS + L VT+
Sbjct: 393 ALTVAGSILAKAQLEVTD 410
Score = 36.6 bits (83), Expect = 0.031
Identities = 46/186 (24%), Positives = 72/186 (38%), Gaps = 22/186 (11%)
Query: 62 VQPGKP-ISESHPILYFTNGHLYPT--GSKSK-RVSLLQNPPTVGVATLKLTDVHPSDTG 117
V G+P I E P GH PT K K R+ + ++ L +++ SD G
Sbjct: 144 VAAGEPAILECQP----PRGHPEPTIYWKKDKVRIDDKEERISIRGGKLMISNTRKSDAG 199
Query: 118 TYLCQVNNPPDFYTNGLGLINL----TVLVPPSNPLCSQSGQTSVGGSTALRCSSSEGAP 173
Y C N + + + T L P N + + + RC +G P
Sbjct: 200 MYTCVGTNMVGERDSDPAELTVFERPTFLRRPINQVVLEEE------AVEFRCQV-QGDP 252
Query: 174 KPVYNWVRLGTFPTPSPGSMVQDEVSGQLILTNLSLTSSGTYRCVATNQMGSASCELTLS 233
+P W + P ++D+ + L + T GTY C+A N++G TL+
Sbjct: 253 QPTVRWKK-DDADLPRGRYDIKDDYT--LRIKKTMSTDEGTYMCIAENRVGKMEASATLT 309
Query: 234 VTEPSQ 239
V P Q
Sbjct: 310 VRAPPQ 315
Score = 30.4 bits (67), Expect = 2.2
Identities = 25/78 (32%), Positives = 30/78 (38%), Gaps = 9/78 (11%)
Query: 157 SVGGSTALRCSSSEGAPKPVYNWVRLGT---FPTPSPGSMVQDEVSGQLILTNL-----S 208
S G T L C + EG P P W + G P S SG L + S
Sbjct: 43 SKGEPTTLNCKA-EGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRRS 101
Query: 209 LTSSGTYRCVATNQMGSA 226
G+Y CVA N +G A
Sbjct: 102 KPDEGSYVCVARNYLGEA 119
>gi|121674801 hepatocyte cell adhesion molecule [Homo sapiens]
Length = 416
Score = 69.3 bits (168), Expect = 4e-12
Identities = 68/270 (25%), Positives = 120/270 (44%), Gaps = 15/270 (5%)
Query: 24 VEVKVPTEPLSTPLGKTAELTCTYSTSVGDSFALEWSFVQPGKPISESHPILYFTNGHLY 83
V + P + +GK+A L+ YS++ D ++W ++ KP++ I G L
Sbjct: 34 VNITSPVRLIHGTVGKSALLSVQYSSTSSDRPVVKWQ-LKRDKPVTVVQSIGTEVIGTLR 92
Query: 84 PTGSKSKRVSLLQNPPTVGVATLKLTDVHPSDTGTYLCQVNNPPDFYTNGLGLINLTVLV 143
P R+ L +N +L L+D+ +D GTY +++ D +T G INLTV V
Sbjct: 93 P--DYRDRIRLFEN------GSLLLSDLQLADEGTYEVEISITDDTFT-GEKTINLTVDV 143
Query: 144 PPSNP--LCSQSGQTSVGGSTALRCSSSEGAPKPVYNWVRLGTFPTPSPGSMVQDEVSGQ 201
P S P L + + + + L CS G KP Y W++ G P + M+
Sbjct: 144 PISRPQVLVASTTVLELSEAFTLNCSHENGT-KPSYTWLKDGK-PLLNDSRMLLSPDQKV 201
Query: 202 LILTNLSLTSSGTYRCVATNQMGSA-SCELTLSVTEPSQGRVAGALIGVLLGVLLLSVAA 260
L +T + + Y C+ N + S + ++V S + + G+ L V L++V A
Sbjct: 202 LTITRVLMEDDDLYSCMVENPISQGRSLPVKITVYRRSSLYIILSTGGIFLLVTLVTVCA 261
Query: 261 FCLVRFQKERGKKPKETYGGSDLREDAIAP 290
+K++ + + + D +D + P
Sbjct: 262 CWKPSKRKQKKLEKQNSLEYMDQNDDRLKP 291
>gi|10864029 junctional adhesion molecule 2 precursor [Homo sapiens]
Length = 298
Score = 65.1 bits (157), Expect = 8e-11
Identities = 52/183 (28%), Positives = 78/183 (42%), Gaps = 16/183 (8%)
Query: 106 LKLTDVHPSDTGTYLCQVNNPPDFYTN-GLGLINLTVLVPPSNPLCSQSGQTSVGGSTAL 164
+++ +V SD G Y C+V+ P + N + L VLV P+ P C G L
Sbjct: 94 IRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTVVEL 153
Query: 165 RCSSSEGAPKPVYNWV----------RLGTFPTPSPGSMVQDEVSGQLILTNLSLTSSGT 214
RC EG P P Y W RLG+ T S S + +G L +S +G
Sbjct: 154 RCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNS--SYTMNTKTGTLQFNTVSKLDTGE 211
Query: 215 YRCVATNQMGSASCELTLSVTEPSQGRVAGALIGVLLGVLLLSVAAFCLVRFQKERGKKP 274
Y C A N +G C + ++G + V++ L++SV V + + +G
Sbjct: 212 YSCEARNSVGYRRCPGKRMQVDDL--NISGIIAAVVVVALVISVCGLG-VCYAQRKGYFS 268
Query: 275 KET 277
KET
Sbjct: 269 KET 271
>gi|28373126 contactin 4 isoform c precursor [Homo sapiens]
Length = 698
Score = 64.3 bits (155), Expect = 1e-10
Identities = 48/176 (27%), Positives = 79/176 (44%), Gaps = 5/176 (2%)
Query: 79 NGHLYPTGS--KSKRVSLLQNPPTVGVATLKLTDVHPSDTGTYLCQVNNPPDFYTNGLGL 136
NG PT K+ L ++ + TL +T V+ SD G Y C N + L
Sbjct: 12 NGRPKPTYKWLKNGEPLLTRDRIQIEQGTLNITIVNLSDAGMYQCLAENKHGVIFSNAEL 71
Query: 137 INLTVLVPPSNPLCSQSGQTSVGGSTALRCSSSEGAPKPVYNWVRLGTFPTPSPGSMVQD 196
+ V S L + VGG + C + +PKPVY W + + + +
Sbjct: 72 SVIAVGPDFSRTLLKRVTLVKVGGEVVIECKP-KASPKPVYTWKKGRDILKENERITISE 130
Query: 197 EVSGQLILTNLSLTSSGTYRCVATNQMGSASCELTLSVTEPSQGRVAGALIGVLLG 252
+ G L + N++ + +G+Y C+ATN G+AS L V +P++ V + + V +G
Sbjct: 131 D--GNLRIINVTKSDAGSYTCIATNHFGTASSTGNLVVKDPTRVMVPPSSMDVTVG 184
Score = 40.8 bits (94), Expect = 0.002
Identities = 35/137 (25%), Positives = 64/137 (46%), Gaps = 18/137 (13%)
Query: 169 SEGAPKPVYNWVRLGTFPTPSPGSMVQDEV---SGQLILTNLSLTSSGTYRCVATNQMG- 224
+ G PKP Y W++ G + +D + G L +T ++L+ +G Y+C+A N+ G
Sbjct: 11 ANGRPKPTYKWLKNG------EPLLTRDRIQIEQGTLNITIVNLSDAGMYQCLAENKHGV 64
Query: 225 -SASCELTLSVTEPSQGRVAGALIGVLLGVLLLSVAAFCLVRFQKERGKKPKETY-GGSD 282
++ EL++ P R +L V L+ V ++ + + KP T+ G D
Sbjct: 65 IFSNAELSVIAVGPDFSRT------LLKRVTLVKVGGEVVIECKPKASPKPVYTWKKGRD 118
Query: 283 LREDAIAPGISEHTCMR 299
+ ++ ISE +R
Sbjct: 119 ILKENERITISEDGNLR 135
>gi|28373122 contactin 4 isoform a precursor [Homo sapiens]
Length = 1026
Score = 64.3 bits (155), Expect = 1e-10
Identities = 48/176 (27%), Positives = 79/176 (44%), Gaps = 5/176 (2%)
Query: 79 NGHLYPTGS--KSKRVSLLQNPPTVGVATLKLTDVHPSDTGTYLCQVNNPPDFYTNGLGL 136
NG PT K+ L ++ + TL +T V+ SD G Y C N + L
Sbjct: 340 NGRPKPTYKWLKNGEPLLTRDRIQIEQGTLNITIVNLSDAGMYQCLAENKHGVIFSNAEL 399
Query: 137 INLTVLVPPSNPLCSQSGQTSVGGSTALRCSSSEGAPKPVYNWVRLGTFPTPSPGSMVQD 196
+ V S L + VGG + C + +PKPVY W + + + +
Sbjct: 400 SVIAVGPDFSRTLLKRVTLVKVGGEVVIECKP-KASPKPVYTWKKGRDILKENERITISE 458
Query: 197 EVSGQLILTNLSLTSSGTYRCVATNQMGSASCELTLSVTEPSQGRVAGALIGVLLG 252
+ G L + N++ + +G+Y C+ATN G+AS L V +P++ V + + V +G
Sbjct: 459 D--GNLRIINVTKSDAGSYTCIATNHFGTASSTGNLVVKDPTRVMVPPSSMDVTVG 512
Score = 42.4 bits (98), Expect = 6e-04
Identities = 63/282 (22%), Positives = 110/282 (39%), Gaps = 51/282 (18%)
Query: 24 VEVKVPTEPLSTPLGKTAELTCTYSTSVGDSFALEWSFVQPGKPISESHPILYFTNGHLY 83
+EV+ P E + T G T +L C FAL G P+ P + +
Sbjct: 227 IEVQFP-ETVPTAKGATVKLEC---------FAL-------GNPV----PTIIWRRADGK 265
Query: 84 PTGSKSKRVSLLQNPPTVGVATLKLTDVHPSDTGTYLCQVNNPPDFYTNGLGLINLTVLV 143
P K++R L++ + D G Y C N + LT
Sbjct: 266 PIARKARRHK--------SNGILEIPNFQQEDAGLYECVAENSRG---KNVARGQLTFYA 314
Query: 144 PPSNPLCSQSGQTSVGGSTALRCSSSEGAPKPVYNWVRLGTFPTPSPGSMVQDEV---SG 200
P+ ++ + C ++ G PKP Y W++ G + +D + G
Sbjct: 315 QPNWIQKINDIHVAMEENVFWECKAN-GRPKPTYKWLKNG------EPLLTRDRIQIEQG 367
Query: 201 QLILTNLSLTSSGTYRCVATNQMG--SASCELTLSVTEPSQGRVAGALIGVLLGVLLLSV 258
L +T ++L+ +G Y+C+A N+ G ++ EL++ P R +L V L+ V
Sbjct: 368 TLNITIVNLSDAGMYQCLAENKHGVIFSNAELSVIAVGPDFSRT------LLKRVTLVKV 421
Query: 259 AAFCLVRFQKERGKKPKETY-GGSDLREDAIAPGISEHTCMR 299
++ + + KP T+ G D+ ++ ISE +R
Sbjct: 422 GGEVVIECKPKASPKPVYTWKKGRDILKENERITISEDGNLR 463
Score = 35.8 bits (81), Expect = 0.053
Identities = 35/136 (25%), Positives = 47/136 (34%), Gaps = 29/136 (21%)
Query: 106 LKLTDVHPSDTGTYLCQVNNPPDFYTNGLGLINLTVLVPPSNPLCSQSG----------- 154
L + V SD G Y C V N + N VL PP+ + G
Sbjct: 179 LYIAKVEKSDVGNYTCVVTNT---------VTNHKVLGPPTPLILRNDGVMGEYEPKIEV 229
Query: 155 ------QTSVGGSTALRCSSSEGAPKPVYNWVRLGTFPTPSPGSMVQDEVSGQLILTNLS 208
T+ G + L C + G P P W R P + + +G L + N
Sbjct: 230 QFPETVPTAKGATVKLECFAL-GNPVPTIIWRRADGKPIARKAR--RHKSNGILEIPNFQ 286
Query: 209 LTSSGTYRCVATNQMG 224
+G Y CVA N G
Sbjct: 287 QEDAGLYECVAENSRG 302
Score = 33.5 bits (75), Expect = 0.26
Identities = 20/57 (35%), Positives = 28/57 (49%), Gaps = 2/57 (3%)
Query: 170 EGAPKPVYNWVRLGTFPTPSPGSMVQDEVSGQLILTNLSLTS-SGTYRCVATNQMGS 225
+G PKP W GT + V G L++ N + T +GTY+C ATN G+
Sbjct: 53 KGNPKPHIRWKLNGT-DVDTGMDFRYSVVEGSLLINNPNKTQDAGTYQCTATNSFGT 108
>gi|98986445 carcinoembryonic antigen-related cell adhesion molecule
5 preproprotein [Homo sapiens]
Length = 702
Score = 62.8 bits (151), Expect = 4e-10
Identities = 51/194 (26%), Positives = 86/194 (44%), Gaps = 24/194 (12%)
Query: 66 KPISESHPILYFTNGHLYPTGSKSKRVSLLQNPPTVGVATLKLTDVHPSDTGTYLCQVNN 125
+P +++ L++ NG P S R+ L G TL L +V +D Y+C + N
Sbjct: 524 EPEAQNTTYLWWVNGQSLPV---SPRLQLSN-----GNRTLTLFNVTRNDARAYVCGIQN 575
Query: 126 PPDFYTNGLGLINLTVLVPPSNPLCSQSGQTSVGGSTALRCSSSEGAPKPVYNWVRLGTF 185
N + L VL P P+ S + + G+ S P P Y+W R+
Sbjct: 576 SVS--ANRSDPVTLDVLYGPDTPIISPPDSSYLSGANLNLSCHSASNPSPQYSW-RINGI 632
Query: 186 PTPSPGSMVQDEVSGQLILTNLSLTSSGTYRC----VATNQMGSASCELTLSVTEPSQGR 241
P + + L + ++ ++GTY C +AT + S +T+S + S G
Sbjct: 633 P---------QQHTQVLFIAKITPNNNGTYACFVSNLATGRNNSIVKSITVSASGTSPGL 683
Query: 242 VAGALIGVLLGVLL 255
AGA +G+++GVL+
Sbjct: 684 SAGATVGIMIGVLV 697
Score = 46.2 bits (108), Expect = 4e-05
Identities = 39/156 (25%), Positives = 64/156 (41%), Gaps = 20/156 (12%)
Query: 66 KPISESHPILYFTNGHLYPTGSKSKRVSLLQNPPTVGVATLKLTDVHPSDTGTYLCQVNN 125
+P ++ L++ N P S R+ L G TL L +V +DT +Y C+ N
Sbjct: 168 EPETQDATYLWWVNNQSLPV---SPRLQLSN-----GNRTLTLFNVTRNDTASYKCETQN 219
Query: 126 PPDFYTNGLGLINLTVLVPPSNPLCSQSGQTSVGGSTALRCSSSEGAPKPVYNWVRLGTF 185
P + ++N VL P P S + G + P Y+W GTF
Sbjct: 220 PVSARRSDSVILN--VLYGPDAPTISPLNTSYRSGENLNLSCHAASNPPAQYSWFVNGTF 277
Query: 186 PTPSPGSMVQDEVSGQLILTNLSLTSSGTYRCVATN 221
+ + +L + N+++ +SG+Y C A N
Sbjct: 278 ----------QQSTQELFIPNITVNNSGSYTCQAHN 303
Score = 37.0 bits (84), Expect = 0.024
Identities = 33/132 (25%), Positives = 55/132 (41%), Gaps = 14/132 (10%)
Query: 105 TLKLTDVHPSDTGTYLCQVNNPPDFYTNGLGLINLTVLVPPSNPLCSQS-GQTSVGGSTA 163
TL L V +D G Y C + N + ++N VL P +P S S G + +
Sbjct: 377 TLTLLSVTRNDVGPYECGIQNKLSVDHSDPVILN--VLYGPDDPTISPSYTYYRPGVNLS 434
Query: 164 LRCSSSEGAPKPVYNWVRLGTFPTPSPGSMVQDEVSGQLILTNLSLTSSGTYRCVATNQM 223
L C ++ P Y+W+ G + + +L ++N++ +SG Y C A N
Sbjct: 435 LSCHAASNPPAQ-YSWLIDGNI----------QQHTQELFISNITEKNSGLYTCQANNSA 483
Query: 224 GSASCELTLSVT 235
S ++T
Sbjct: 484 SGHSRTTVKTIT 495
>gi|13376852 CD276 antigen isoform b [Homo sapiens]
Length = 316
Score = 62.0 bits (149), Expect = 7e-10
Identities = 75/288 (26%), Positives = 126/288 (43%), Gaps = 31/288 (10%)
Query: 11 GALLGFL--CLSGLAVEVKVPTEPLSTPLGKTAELTCTYSTSVGDSFA---LEWSFVQPG 65
GA LG L CL+G A+EV+VP +P+ +G A L C++S G S A L W
Sbjct: 15 GAALGALWFCLTG-ALEVQVPEDPVVALVGTDATLCCSFSPEPGFSLAQLNLIWQLTDTK 73
Query: 66 KPISESHPILYFTNGHLYPTGSK-SKRVSLLQNPPTVGVATLKLTDVHPSDTGTYLCQVN 124
+ + F G GS + R +L + G A+L+L V +D G++ C V
Sbjct: 74 QLVHS------FAEGQ--DQGSAYANRTALFPDLLAQGNASLRLQRVRVADEGSFTCFV- 124
Query: 125 NPPDFYTNGLGLINLTVLVPPSNPLCSQSGQTSV--GGSTALRCSSSEGAPKPVYNWVRL 182
+ DF G ++L V P S P + + G + + CSS G P+ W
Sbjct: 125 SIRDF---GSAAVSLQVAAPYSKPSMTLEPNKDLRPGDTVTITCSSYRGYPEAEVFW--Q 179
Query: 183 GTFPTPSPGSMVQDEVSGQLILTNLS------LTSSGTYRCVATNQMGSASCELTLSVT- 235
P G++ +++ + L ++ L ++GTY C+ N + ++++T
Sbjct: 180 DGQGVPLTGNVTTSQMANEQGLFDVHSVLRVVLGANGTYSCLVRNPVLQQDAHGSVTITG 239
Query: 236 EPSQGRVAGALIGVLLGVLLLS-VAAFCLVRFQKERGKKPKETYGGSD 282
+P + V L V L++ + A V ++K + +E G D
Sbjct: 240 QPMTFPPEALWVTVGLSVCLIALLVALAFVCWRKIKQSCEEENAGAED 287
>gi|118572606 hemicentin 1 [Homo sapiens]
Length = 5635
Score = 60.8 bits (146), Expect = 2e-09
Identities = 41/133 (30%), Positives = 62/133 (46%), Gaps = 5/133 (3%)
Query: 105 TLKLTDVHPSDTGTYLCQVNNPPDFYTNGLGLINLTVLVPPSNPLCSQSGQTSVGGSTAL 164
++K+T+ SD+G YLC N T + L V VPP + + VG +
Sbjct: 1134 SMKITETRTSDSGMYLCVATNIAGNVTQA---VKLNVHVPPKIQRGPKHLKVQVGQRVDI 1190
Query: 165 RCSSSEGAPKPVYNWVRLGTFPTPSPGSMVQDEVSGQLILTNLSLTSSGTYRCVATNQMG 224
C++ +G P PV W + G+ V + G L + + + +G Y CVATN G
Sbjct: 1191 PCNA-QGTPLPVITWSKGGSTMLVDGEHHVSNP-DGTLSIDQATPSDAGIYTCVATNIAG 1248
Query: 225 SASCELTLSVTEP 237
+ E+TL V EP
Sbjct: 1249 TDETEITLHVQEP 1261
Score = 57.0 bits (136), Expect = 2e-08
Identities = 50/154 (32%), Positives = 65/154 (42%), Gaps = 14/154 (9%)
Query: 99 PTVGVATLKLTDVHPSDTGTYLCQVNNPPDFYTNGLGLINLTVLVPPSNPLCSQSGQTSV 158
P +G+ LK+ + D G Y C N T G I L V PP +
Sbjct: 752 PLLGL--LKIQETQDLDAGDYTCVAINEAGRAT---GKITLDVGSPPVFIQEPADVSMEI 806
Query: 159 GGSTALRCSSSEGAPKPVYNWVRLGTFPT---PSPGSMVQDEVSGQLILTNLSLTSSGTY 215
G + L C +G P+P W RL P P S + +G L + NL + GTY
Sbjct: 807 GSNVTLPCYV-QGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTY 865
Query: 216 RCVATNQMGSASCELTLSVTEPSQGRVAGALIGV 249
C A NQ G E T++VT G VA LIG+
Sbjct: 866 ICEAENQFGKIQSETTVTVT----GLVA-PLIGI 894
Score = 55.5 bits (132), Expect = 7e-08
Identities = 50/163 (30%), Positives = 66/163 (40%), Gaps = 19/163 (11%)
Query: 79 NGHLYPTGSKSKRVSLLQNPPTVGVATLKLTDVHPSDTGTYLCQVNNPPDFYTNGLG--- 135
NGHL LL + +L + DT TY C V TNG G
Sbjct: 3840 NGHLLNVDQNQNSYRLLSS------GSLVIISPSVDDTATYECTV-------TNGAGDDK 3886
Query: 136 -LINLTVLVPPSNPLCSQSGQTSVGGSTALRCSSSEGAPKPVYNWVRLGTFPTPSPGSMV 194
++LTV VPPS + + C++S G P P +W + G P G
Sbjct: 3887 RTVDLTVQVPPSIADEPTDFLVTKHAPAVITCTAS-GVPFPSIHWTKNGIRLLPR-GDGY 3944
Query: 195 QDEVSGQLILTNLSLTSSGTYRCVATNQMGSASCELTLSVTEP 237
+ SG + + L +G Y CVA N GSA +TL V EP
Sbjct: 3945 RILSSGAIEILATQLNHAGRYTCVARNAAGSAHRHVTLHVHEP 3987
Score = 53.5 bits (127), Expect = 2e-07
Identities = 42/131 (32%), Positives = 58/131 (44%), Gaps = 7/131 (5%)
Query: 105 TLKLTDVHPSDTGTYLCQVNNPPDFYTNGLGLINLTVLVPPSNPLCSQSGQTSVG-GSTA 163
+L++ V P D G Y C N + LTV VPP + S G +V S A
Sbjct: 4132 SLQIAFVQPGDAGHYTCMAANVAGSSSTST---KLTVHVPPR--IRSTEGHYTVNENSQA 4186
Query: 164 LRCSSSEGAPKPVYNWVRLGTFPTPSPGSMVQDEVSGQLILTNLSLTSSGTYRCVATNQM 223
+ ++G P P NW + G E G+LIL N+ L SG Y CVA N
Sbjct: 4187 ILPCVADGIPTPAINWKKDNVLLANLLGKYTA-EPYGELILENVVLEDSGFYTCVANNAA 4245
Query: 224 GSASCELTLSV 234
G + ++L+V
Sbjct: 4246 GEDTHTVSLTV 4256
Score = 52.8 bits (125), Expect = 4e-07
Identities = 67/246 (27%), Positives = 95/246 (38%), Gaps = 35/246 (14%)
Query: 15 GFLCLSGLAVEVKVPTEPLSTPLGKTAELTCTYSTSVGDSF------ALEWSFVQPGKPI 68
G+ LS A+E+ L+T L TC + G + E +QP
Sbjct: 3943 GYRILSSGAIEI------LATQLNHAGRYTCVARNAAGSAHRHVTLHVHEPPVIQPQP-- 3994
Query: 69 SESHPILYFTNGHLYP---TGSKSKRVSLLQNPPTVGVAT----------LKLTDVHPSD 115
SE H IL N L P TG+ S ++ + V + L+++ D
Sbjct: 3995 SELHVIL--NNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGGLQISRAVRED 4052
Query: 116 TGTYLCQVNNPPDFYTNGLGLINLTVLVPPSNPLCSQSGQTSVGGSTALRCSSSEGAPKP 175
GTY+C NP LG I L V VPP + +V L C + +G P P
Sbjct: 4053 AGTYMCVAQNPAG---TALGKIKLNVQVPPVISPHLKEYVIAVDKPITLSCEA-DGLPPP 4108
Query: 176 VYNWVRLGTFPTPSPGSMVQDEVSGQLILTNLSLTSSGTYRCVATNQMGSASCELTLSVT 235
W + G S V SG L + + +G Y C+A N GS+S L+V
Sbjct: 4109 DITWHKDGRAIVESIRQRVLS--SGSLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVH 4166
Query: 236 EPSQGR 241
P + R
Sbjct: 4167 VPPRIR 4172
Score = 50.4 bits (119), Expect = 2e-06
Identities = 55/215 (25%), Positives = 94/215 (43%), Gaps = 36/215 (16%)
Query: 27 KVPTEPLSTPLGKTAELTCTYSTSVGDSFALEWSFVQPGKPISESHPILYFTNGHLYPTG 86
++P++ +S LG+ EL C + + ++W ++ GKPI+
Sbjct: 3251 EIPSD-VSVLLGENVELVCNANGI--PTPLIQW--LKDGKPIASG--------------- 3290
Query: 87 SKSKRVSLLQNPPTVGVATLKLTDVHPSDTGTYLCQVNNPPDFYTNGLGLINLTVLVPPS 146
+++R+ + N +TL + SDTG Y C NP + NL V V P+
Sbjct: 3291 -ETERIRVSANG-----STLNIYGALTSDTGKYTCVATNPAGEEDR---IFNLNVYVTPT 3341
Query: 147 ---NPLCSQSGQTSVGGSTALRCSSSEGAPKPVYNWVRLGTFPTPSPGSMVQDEVSGQLI 203
N ++ T V S + C ++ G P P NW++ G P P S ++ +GQ+I
Sbjct: 3342 IRGNKDEAEKLMTLVDTSINIECRAT-GTPPPQINWLKNG-LPLPL-SSHIRLLAAGQVI 3398
Query: 204 -LTNLSLTSSGTYRCVATNQMGSASCELTLSVTEP 237
+ ++ Y CVA+N+ G + L V P
Sbjct: 3399 RIVRAQVSDVAVYTCVASNRAGVDNKHYNLQVFAP 3433
Score = 48.1 bits (113), Expect = 1e-05
Identities = 40/153 (26%), Positives = 67/153 (43%), Gaps = 6/153 (3%)
Query: 100 TVGVATLKLTDVHPSDTGTYLCQVNNPPDFYTNGLGLINLTVLVPPSNPLCSQSGQTSVG 159
T+ +L+L V +D G Y C V++ + + LTV PP + ++ + G
Sbjct: 570 TLANLSLELKSVKFNDAGEYHCMVSSEGG---SSAASVFLTVQEPPKVTVMPKNQSFTGG 626
Query: 160 GSTALRCSSSEGAPKPVYNWVRLGTFPTPSPGSMVQDEVSGQLILTNLSLTSSGTYRCVA 219
++ CS++ G PKP W F S + + G L + N + +G Y C+A
Sbjct: 627 SEVSIMCSAT-GYPKPKIAWTVNDMFIVGSHRYRMTSD--GTLFIKNAAPKDAGIYGCLA 683
Query: 220 TNQMGSASCELTLSVTEPSQGRVAGALIGVLLG 252
+N G+ TL E + V + + V LG
Sbjct: 684 SNSAGTDKQNSTLRYIEAPKLMVVQSELLVALG 716
Score = 47.8 bits (112), Expect = 1e-05
Identities = 57/235 (24%), Positives = 89/235 (37%), Gaps = 29/235 (12%)
Query: 19 LSGLAVEVKVPTEPLSTPLGKTAELTCTYSTSVGDSFALEWSFVQPGKPISESHPILYFT 78
L+ L++E+K S E C S+ G S A + VQ ++ FT
Sbjct: 571 LANLSLELK------SVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPPKVTVMPKNQSFT 624
Query: 79 NGH-----LYPTGSKSKRVSLLQNPPTV---------GVATLKLTDVHPSDTGTYLCQVN 124
G TG +++ N + TL + + P D G Y C +
Sbjct: 625 GGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTSDGTLFIKNAAPKDAGIYGCLAS 684
Query: 125 NPP--DFYTNGLGLINLTVLVPPSNPLCSQSGQTSVGGSTALRCSSSEGAPKPVYNWVRL 182
N D + L I L+ + L ++G T + C +S G P P W +
Sbjct: 685 NSAGTDKQNSTLRYIEAPKLMVVQSELL-----VALGDITVMECKTS-GIPPPQVKWFKG 738
Query: 183 GTFPTPSPGSMVQDEVSGQLILTNLSLTSSGTYRCVATNQMGSASCELTLSVTEP 237
PS ++ D + G L + +G Y CVA N+ G A+ ++TL V P
Sbjct: 739 DLELRPST-FLIIDPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGSP 792
Score = 47.4 bits (111), Expect = 2e-05
Identities = 36/134 (26%), Positives = 53/134 (39%), Gaps = 7/134 (5%)
Query: 106 LKLTDVHPSDTGTYLCQVNNPPDFYTNGLGLINLTVLVPPS--NPLCSQSGQTSVGGSTA 163
+++ SD Y C +N NL V PP+ N + ++ G ST+
Sbjct: 3398 IRIVRAQVSDVAVYTCVASNRAGVDNKHY---NLQVFAPPNMDNSMGTEEITVLKGSSTS 3454
Query: 164 LRCSSSEGAPKPVYNWVRLGTFPTPSPGSMVQDEVSGQLILTNLSLTSSGTYRCVATNQM 223
+ C + +G P P W+R G P + L L SG Y C+A+N+
Sbjct: 3455 MACIT-DGTPAPSMAWLRDGQ-PLGLDAHLTVSTHGMVLQLLKAETEDSGKYTCIASNEA 3512
Query: 224 GSASCELTLSVTEP 237
G S L V EP
Sbjct: 3513 GEVSKHFILKVLEP 3526
Score = 47.0 bits (110), Expect = 2e-05
Identities = 40/134 (29%), Positives = 58/134 (43%), Gaps = 7/134 (5%)
Query: 104 ATLKLTDVHPSDTGTYLCQVNNPPDFYTNGLGLINLTVLVPPSNPLCSQSGQTSV--GGS 161
+ LK+ D DTG Y C+ N N+ + VPP+ + Q +V G
Sbjct: 2157 SVLKIEDAQVQDTGRYTCEATNVAGKTEKN---YNVNIWVPPNIGGSDELTQLTVIEGNL 2213
Query: 162 TALRCSSSEGAPKPVYNWVRLGT-FPTPSPGSMVQDEVSGQLILTNLSLTSSGTYRCVAT 220
+L C SS G P P W + G+ T S G + QL ++ + + Y CVA+
Sbjct: 2214 ISLLCESS-GIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVAS 2272
Query: 221 NQMGSASCELTLSV 234
N G+A E L V
Sbjct: 2273 NVAGTAKKEYNLQV 2286
Score = 45.8 bits (107), Expect = 5e-05
Identities = 38/143 (26%), Positives = 57/143 (39%), Gaps = 5/143 (3%)
Query: 106 LKLTDVHPSDTGTYLCQVNNPPDFYTNGLGLINLTVLVPPSNPLCSQSGQTSVGGS-TAL 164
L + S+TG Y C N + +TV VPP+ S + V AL
Sbjct: 1790 LVIAQAQVSNTGLYRCMAANTAGDHKKEF---EVTVHVPPTIKSSGLSERVVVKYKPVAL 1846
Query: 165 RCSSSEGAPKPVYNWVRLGTFPTPSPGSMVQDEVSGQLILTNLSLTSSGTYRCVATNQMG 224
+C ++ G P P W++ + G++ L + L +G Y CVATN G
Sbjct: 1847 QCIAN-GIPNPSITWLKDDQPVNTAQGNLKIQSSGRVLQIAKTLLEDAGRYTCVATNAAG 1905
Query: 225 SASCELTLSVTEPSQGRVAGALI 247
+ L V EP AG ++
Sbjct: 1906 ETQQHIQLHVHEPPSLEDAGKML 1928
Score = 45.8 bits (107), Expect = 5e-05
Identities = 37/136 (27%), Positives = 54/136 (39%), Gaps = 5/136 (3%)
Query: 102 GVATLKLTDVHPSDTGTYLCQVNNPPDFYTNGLGLINLTVLVPPSNPLCSQSGQTSVGGS 161
G L LT SDTG Y C N I+L V VPP+ Q+ + +
Sbjct: 2064 GGRILALTSAQISDTGRYTCVAVNAAGEKQRD---IDLRVYVPPNIMGEEQNVSVLISQA 2120
Query: 162 TALRCSSSEGAPKPVYNWVRLGTFPTPSPGSMVQDEVSGQLILTNLSLTSSGTYRCVATN 221
L C S+ P P W++ G PG + + S L + + + +G Y C ATN
Sbjct: 2121 VELLC-QSDAIPPPTLTWLKDGHPLLKKPGLSISENRS-VLKIEDAQVQDTGRYTCEATN 2178
Query: 222 QMGSASCELTLSVTEP 237
G +++ P
Sbjct: 2179 VAGKTEKNYNVNIWVP 2194
Score = 44.7 bits (104), Expect = 1e-04
Identities = 31/120 (25%), Positives = 50/120 (41%), Gaps = 3/120 (2%)
Query: 106 LKLTDVHPSDTGTYLCQVNNPPDFYTNGLGLINLTVLVPPSNPLCSQSGQTSVGGSTALR 165
L + ++ SD GTY+C+ N + + +T LV P + G L
Sbjct: 852 LFILNLWASDKGTYICEAENQFGKIQSET-TVTVTGLVAPLIGISPSVANVIEGQQLTLP 910
Query: 166 CSSSEGAPKPVYNWVRLGTFPTPSPGSMVQDEVSGQLILTNLSLTSSGTYRCVATNQMGS 225
C+ G P P W++ +P V+ + G L + + L G Y CVA+N G+
Sbjct: 911 CTLLAGNPIPERRWIKNSAMLLQNPYITVRSD--GSLHIERVQLQDGGEYTCVASNVAGT 968
Score = 44.3 bits (103), Expect = 2e-04
Identities = 43/147 (29%), Positives = 62/147 (42%), Gaps = 9/147 (6%)
Query: 95 LQNPPTVGVAT----LKLTDVHPSDTGTYLCQVNNPPDFYTNGLGLINLTVLVPPSNPLC 150
LQ P V + + L++ + DT Y C +N T LTV VPP+
Sbjct: 3662 LQATPRVRILSGGRYLQINNADLGDTANYTCVASNIAGKTTREF---ILTVNVPPNIKGG 3718
Query: 151 SQSGQTSVGGSTALRCSSSEGAPKPVYNWVRLGTFPTPSPGSMVQDEVSGQLILTNLSLT 210
QS + ST L C + EG P P W + G + E +G L + + +T
Sbjct: 3719 PQSLVILLNKSTVLECIA-EGVPTPRITWRKDGAVLAGNHARYSILE-NGFLHIQSAHVT 3776
Query: 211 SSGTYRCVATNQMGSASCELTLSVTEP 237
+G Y C+ATN G+ + L V P
Sbjct: 3777 DTGRYLCMATNAAGTDRRRIDLQVHVP 3803
Score = 43.9 bits (102), Expect = 2e-04
Identities = 37/138 (26%), Positives = 57/138 (41%), Gaps = 9/138 (6%)
Query: 105 TLKLTDVHPSDTGTYLCQVNNPPDFYTNGLGLINLTVLVPPS----NPLCSQSGQTSVGG 160
TL + PSD G Y C N I L V PP+ P + + Q V
Sbjct: 1225 TLSIDQATPSDAGIYTCVATNIAGTDETE---ITLHVQEPPTVEDLEPPYNTTFQERVAN 1281
Query: 161 STALRCSSSEGAPKPVYNWVRLGTFPTP-SPGSMVQDEVSGQLILTNLSLTSSGTYRCVA 219
++G PKP W+ G T PG + ++ + L++ +++ +G Y CVA
Sbjct: 1282 QRIEFPCPAKGTPKPTIKWLHNGRELTGREPGISILEDGT-LLVIASVTPYDNGEYICVA 1340
Query: 220 TNQMGSASCELTLSVTEP 237
N+ G+ + L V P
Sbjct: 1341 VNEAGTTERKYNLKVHVP 1358
Score = 43.9 bits (102), Expect = 2e-04
Identities = 38/137 (27%), Positives = 57/137 (41%), Gaps = 7/137 (5%)
Query: 102 GVATLKLTDVHPSDTGTYLCQVNNPPDFYTNGLGLINLTVLVPPSNPLCSQSGQTS-VGG 160
G + L + V D+GTY+C N F +G + V PP S +GG
Sbjct: 4309 GHSELVIERVSKEDSGTYVCTAENSVGF-VKAIGFVY--VKEPPVFKGDYPSNWIEPLGG 4365
Query: 161 STALRCSSSEGAPKPVYNWVRLGTFPTPSPGSMVQDEVSGQLILTNLSLTSSGTYRCVAT 220
+ L C +G P P W R G S ++ +G L + +G Y CVAT
Sbjct: 4366 NAILNCEV-KGDPTPTIQWNRKGVDIEIS--HRIRQLGNGSLAIYGTVNEDAGDYTCVAT 4422
Query: 221 NQMGSASCELTLSVTEP 237
N+ G ++L++ P
Sbjct: 4423 NEAGVVERSMSLTLQSP 4439
Score = 43.5 bits (101), Expect = 3e-04
Identities = 39/135 (28%), Positives = 55/135 (40%), Gaps = 8/135 (5%)
Query: 106 LKLTDVHPSDTGTYLCQVNNPPDFYTNGLGLINLTVLVPPS---NPLCSQSGQTSVGGST 162
L+L ++H SDTG Y+C N +L+V PPS N ++ S
Sbjct: 2348 LQLKNIHVSDTGRYVCVAVNVAGMTDKKY---DLSVHAPPSIIGNHRSPENISVVEKNSV 2404
Query: 163 ALRCSSSEGAPKPVYNWVRLGTFPTPSPGSMVQDEVSGQLILTNLSLTSSGTYRCVATNQ 222
+L C +S G P P W + G +P S+ L L ++ +G Y CV N
Sbjct: 2405 SLTCEAS-GIPLPSITWFKDG-WPVSLSNSVRILSGGRMLRLMQTTMEDAGQYTCVVRNA 2462
Query: 223 MGSASCELTLSVTEP 237
G LSV P
Sbjct: 2463 AGEERKIFGLSVLVP 2477
Score = 42.7 bits (99), Expect = 4e-04
Identities = 40/141 (28%), Positives = 59/141 (41%), Gaps = 13/141 (9%)
Query: 102 GVATLKLTDVHPSDTGTYLCQVNNPP-DFYTNGLGLINLTVLVPPSNPLCSQSGQTSV-- 158
G L+++ DTG Y C ++P D L + V VPP+ + +V
Sbjct: 3580 GGEVLRISTAQVEDTGRYTCLASSPAGDDDKEYL----VRVHVPPNIAGTDEPRDITVLR 3635
Query: 159 GGSTALRCSSSEGAPKPVYNWVRLGTFPTPSPGSMVQDEVSG--QLILTNLSLTSSGTYR 216
L C S + P PV W+R G +P + +SG L + N L + Y
Sbjct: 3636 NRQVTLECKS-DAVPPPVITWLRNGERLQATPRVRI---LSGGRYLQINNADLGDTANYT 3691
Query: 217 CVATNQMGSASCELTLSVTEP 237
CVA+N G + E L+V P
Sbjct: 3692 CVASNIAGKTTREFILTVNVP 3712
Score = 42.0 bits (97), Expect = 7e-04
Identities = 51/215 (23%), Positives = 83/215 (38%), Gaps = 47/215 (21%)
Query: 31 EPLSTPLGKTAELTCTYSTSVGDSFALEWSFVQPGKPISESHPILYFTNGHLYPTGSKSK 90
E ++ + K+A + C S S A S+ + G+P+ E + +NG +
Sbjct: 2880 EEVTVLVNKSALIECLSSGSP----APRNSWQKDGQPLLEDDHHKFLSNGRI-------- 2927
Query: 91 RVSLLQNPPTVGVATLKLTDVHPSDTGTYLCQVNNPPDFYTNGLGLINLTVLVPPS--NP 148
L++ + +D G Y+C N + NL V VPPS P
Sbjct: 2928 ---------------LQILNTQITDIGRYVCVAENTAG---SAKKYFNLNVHVPPSVIGP 2969
Query: 149 LCSQSGQTSVGGSTALRCSSSEGAPKPVYNW------VRLGTFPTPSPGSMVQDEVSGQL 202
S++ V +L C S G P P +W ++L T PG L
Sbjct: 2970 K-SENLTVVVNNFISLTCEVS-GFPPPDLSWLKNEQPIKLNTNTLIVPGGRT-------L 3020
Query: 203 ILTNLSLTSSGTYRCVATNQMGSASCELTLSVTEP 237
+ ++ G Y C+A NQ G + + +L+V P
Sbjct: 3021 QIIRAKVSDGGEYTCIAINQAGESKKKFSLTVYVP 3055
Score = 41.6 bits (96), Expect = 0.001
Identities = 37/129 (28%), Positives = 54/129 (41%), Gaps = 14/129 (10%)
Query: 114 SDTGTYLCQVNNPPD----FYTNGLGLINLTVLVPPSNPLCSQSGQTSVGGSTALRCSSS 169
SD G Y C N FY+ L V V PS + V L C +
Sbjct: 1984 SDAGIYKCVAINSAGATELFYS-------LQVHVAPSISGSNNMVAVVVNNPVRLECEA- 2035
Query: 170 EGAPKPVYNWVRLGTFPTPSPGSMVQDEVSGQLI-LTNLSLTSSGTYRCVATNQMGSASC 228
G P P W++ G+ P S + +Q G+++ LT+ ++ +G Y CVA N G
Sbjct: 2036 RGIPAPSLTWLKDGS-PVSSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVNAAGEKQR 2094
Query: 229 ELTLSVTEP 237
++ L V P
Sbjct: 2095 DIDLRVYVP 2103
Score = 41.6 bits (96), Expect = 0.001
Identities = 50/185 (27%), Positives = 78/185 (42%), Gaps = 18/185 (9%)
Query: 74 ILYFTNGHLYPTGSKSKRVSLLQNPPTVGVATLKLTDVHPSDTGTYLCQVNNPPDFYTNG 133
I ++ NG + ++S V +L + + + ++ SDTG Y+C+ N
Sbjct: 3091 ITWYKNGRMI---TESTHVEILADGQMLHIKKAEV-----SDTGQYVCRAINVAGRDDKN 3142
Query: 134 LGLINLTVLVPPS--NPLCSQSGQTSVGGSTALRCSSSEGAPKPVYNWVRLGTFPTPSPG 191
+L V VPPS P +T + L C ++ G P P W++ S
Sbjct: 3143 F---HLNVYVPPSIEGPEREVIVET-ISNPVTLTCDAT-GIPPPTIAWLKNHKRIENSDS 3197
Query: 192 SMVQDEVSG-QLILTNLSLTSSGTYRCVATNQMGSASCELTLSVTEPSQGRVAGALIGVL 250
V+ G +L + + SG Y C+A+N G A LS+ P VAGA I
Sbjct: 3198 LEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQKYYFLSIQVPPS--VAGAEIPSD 3255
Query: 251 LGVLL 255
+ VLL
Sbjct: 3256 VSVLL 3260
Score = 41.2 bits (95), Expect = 0.001
Identities = 42/156 (26%), Positives = 65/156 (41%), Gaps = 10/156 (6%)
Query: 106 LKLTDVHPSDTGTYLCQVNNPPDFYTNGLGLINLTVLVPPSNPLCSQSGQTSV--GGSTA 163
LKL P D G Y C+ N N+ VLVPP+ + + SV A
Sbjct: 1416 LKLFRATPEDAGRYSCKAIN---IAGTSQKYFNIDVLVPPTIIGTNFPNEVSVVLNRDVA 1472
Query: 164 LRCSSSEGAPKPVYNWVRLGTFPTPSPGSMVQDEVSGQLI-LTNLSLTSSGTYRCVATNQ 222
L C +G P P +W + G P V+ GQ++ L N G Y+C +N
Sbjct: 1473 LEC-QVKGTPFPDIHWFKDGK-PLFLGDPNVELLDRGQVLHLKNARRNDKGRYQCTVSNA 1530
Query: 223 MGSASCELTLSVTEPSQGRVAGALIGVLLGVLLLSV 258
G + ++ L++ P + G + + VL+ S+
Sbjct: 1531 AGKQAKDIKLTIYIPPS--IKGGNVTTDISVLINSL 1564
Score = 40.8 bits (94), Expect = 0.002
Identities = 40/141 (28%), Positives = 60/141 (42%), Gaps = 12/141 (8%)
Query: 102 GVATLKLTDVHPSDTGTYLCQVNNPPDFYTNGLGLINLTVLVPPSNPLCSQSGQTSV--- 158
G L+++ SD Y C +N NL V + P+ S S T +
Sbjct: 2250 GGRQLQISIAEKSDAALYSCVASNVAGTAKKEY---NLQVYIRPTITN-SGSHPTEIIVT 2305
Query: 159 -GGSTALRCSSSEGAPKPVYNWVRLGTFPTPSPGSMVQDEVSGQLI-LTNLSLTSSGTYR 216
G S +L C +G P P W++ G + G + DE G ++ L N+ ++ +G Y
Sbjct: 2306 RGKSISLECEV-QGIPPPTVTWMKDGHPLIKAKGVEILDE--GHILQLKNIHVSDTGRYV 2362
Query: 217 CVATNQMGSASCELTLSVTEP 237
CVA N G + LSV P
Sbjct: 2363 CVAVNVAGMTDKKYDLSVHAP 2383
Score = 40.0 bits (92), Expect = 0.003
Identities = 43/143 (30%), Positives = 57/143 (39%), Gaps = 7/143 (4%)
Query: 94 LLQNPPTV--GVATLKLTDVHPSDTGTYLCQVNNPPDFYTNGLGLINLTVLVPPSNPLCS 151
LLQNP +L + V D G Y C +N TN ++ V V P+
Sbjct: 931 LLQNPYITVRSDGSLHIERVQLQDGGEYTCVASNVAG--TNNK-TTSVVVHVLPTIQHGQ 987
Query: 152 QSGQTSVGGSTALRCSSSEGAPKPVYNWVRLGTFPTPSPGSMVQDEVSGQLILTNLSLTS 211
Q T G L C +S G PKP W + G + S G L + +
Sbjct: 988 QILSTIEGIPVTLPCKAS-GNPKPSVIWSKKGELISTSSAKFSAG-ADGSLYVVSPGGEE 1045
Query: 212 SGTYRCVATNQMGSASCELTLSV 234
SG Y C ATN G A ++ L+V
Sbjct: 1046 SGEYVCTATNTAGYAKRKVQLTV 1068
Score = 38.1 bits (87), Expect = 0.011
Identities = 40/139 (28%), Positives = 56/139 (40%), Gaps = 15/139 (10%)
Query: 102 GVATLKLTDVHPSDTGTYLCQVNNPPDFYTNGLGLINLTVLVPP----SNPLCSQSGQTS 157
G L+L D G Y C V N GL +VLVPP N L + +
Sbjct: 2438 GGRMLRLMQTTMEDAGQYTCVVRNAAGEERKIFGL---SVLVPPHIVGENTL--EDVKVK 2492
Query: 158 VGGSTALRCSSSEGAPKPVYNWVRLGTFPTPSPGSMVQDEVSGQ--LILTNLSLTSSGTY 215
S L C + G P P W + G P +SG L +TN+ + +G Y
Sbjct: 2493 EKQSVTLTCEVT-GNPVPEITWHKDGQ---PLQEDEAHHIISGGRFLQITNVQVPHTGRY 2548
Query: 216 RCVATNQMGSASCELTLSV 234
C+A++ G S +L+V
Sbjct: 2549 TCLASSPAGHKSRSFSLNV 2567
Score = 38.1 bits (87), Expect = 0.011
Identities = 39/150 (26%), Positives = 60/150 (40%), Gaps = 27/150 (18%)
Query: 105 TLKLTDVHPSDTGTYLCQVNN-----PPDFYTNGLGLINLTVLVPPS--------NPL-C 150
TL++ + SDTG Y C +N DF N + VPPS N L
Sbjct: 2729 TLQIKEAQISDTGRYTCVASNIAGEDELDFDVN--------IQVPPSFQKLWEIGNMLDT 2780
Query: 151 SQSGQTS---VGGSTALRCSSSEGAPKPVYNWVRLGTFPTPSPGSMVQDEVSGQLILTNL 207
++G+ + +L C ++ AP P W + G P S ++ L +
Sbjct: 2781 GRNGEAKDVIINNPISLYCETN-AAPPPTLTWYKDG-HPLTSSDKVLILPGGRVLQIPRA 2838
Query: 208 SLTSSGTYRCVATNQMGSASCELTLSVTEP 237
+ +G Y CVA N+ G S + + V P
Sbjct: 2839 KVEDAGRYTCVAVNEAGEDSLQYDVRVLVP 2868
Score = 38.1 bits (87), Expect = 0.011
Identities = 45/174 (25%), Positives = 71/174 (40%), Gaps = 29/174 (16%)
Query: 74 ILYFTNGHLYPTGSKSKRVSLLQNPPTVGVATLKLTDVHPSDTGTYLCQVNNPPDFYTNG 133
+ ++ +GH P S K + L G L++ D G Y C N
Sbjct: 2809 LTWYKDGH--PLTSSDKVLIL------PGGRVLQIPRAKVEDAGRYTCVAVNEAG---ED 2857
Query: 134 LGLINLTVLVPP----SNPLCSQSGQTSVGGSTALRCSSSEGAPKPVYNWVRLGTFPTPS 189
++ VLVPP +N + V S + C SS G+P P +W + G
Sbjct: 2858 SLQYDVRVLVPPIIKGANSDLPEEVTVLVNKSALIECLSS-GSPAPRNSWQKDGQ----- 2911
Query: 190 PGSMVQDE-----VSGQLI-LTNLSLTSSGTYRCVATNQMGSASCELTLSVTEP 237
+++D+ +G+++ + N +T G Y CVA N GSA L+V P
Sbjct: 2912 --PLLEDDHHKFLSNGRILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHVP 2963
Score = 36.2 bits (82), Expect = 0.041
Identities = 32/124 (25%), Positives = 51/124 (41%), Gaps = 10/124 (8%)
Query: 106 LKLTDVHPSDTGTYLCQVNNPPDFYTNGLGLINLTVLVPPSNPLCSQSGQTS-----VGG 160
L++T+V TG Y C ++P + +L V V P+ G +
Sbjct: 2535 LQITNVQVPHTGRYTCLASSPAGHKSRSF---SLNVFVSPTIAGVGSDGNPEDVTVILNS 2591
Query: 161 STALRCSSSEGAPKPVYNWVRLGTFPTPSPGSMVQDEVSGQLILTNLSLTSSGTYRCVAT 220
T+L C + P + W + GT P S ++ L + N ++G Y CVAT
Sbjct: 2592 PTSLVCEAYSYPPATI-TWFKDGT-PLESNRNIRILPGGRTLQILNAQEDNAGRYSCVAT 2649
Query: 221 NQMG 224
N+ G
Sbjct: 2650 NEAG 2653
Score = 35.8 bits (81), Expect = 0.053
Identities = 35/133 (26%), Positives = 52/133 (39%), Gaps = 17/133 (12%)
Query: 115 DTGTYLCQVNNPPDFYTNGLGLINLTVLVPPSNPLCSQSGQTS---------VGGSTALR 165
++G Y+C N + + LTV V P Q G + G L
Sbjct: 1045 ESGEYVCTATNTAGYAKRK---VQLTVYVRP-RVFGDQRGLSQDKPVEISVLAGEEVTLP 1100
Query: 166 CSSSEGAPKPVYNWVRLGTFPTP-SPGSMVQDEVSGQLILTNLSLTSSGTYRCVATNQMG 224
C + P P+ W + +P SP SG + +T + SG Y CVATN G
Sbjct: 1101 CEV-KSLPPPIITWAKETQLISPFSPRHTFLP--SGSMKITETRTSDSGMYLCVATNIAG 1157
Query: 225 SASCELTLSVTEP 237
+ + + L+V P
Sbjct: 1158 NVTQAVKLNVHVP 1170
Score = 34.7 bits (78), Expect = 0.12
Identities = 35/148 (23%), Positives = 62/148 (41%), Gaps = 13/148 (8%)
Query: 102 GVATLKLTDVHPSDTGTYLCQVNNPPDFYTNGLGLIN--LTVLVPPSNPLCSQSGQ--TS 157
G L++ D G Y+C + G I + VLVPP+ ++
Sbjct: 1693 GGKKLEIMSAQEIDRGQYICVATS-----VAGEKEIKYEVDVLVPPAIEGGDETSYFIVM 1747
Query: 158 VGGSTALRCSSSEGAPKPVYNWVRLGTFPTPSPGSMVQDEVSGQ-LILTNLSLTSSGTYR 216
V L C + G+P P W++ G G + ++G+ L++ ++++G YR
Sbjct: 1748 VNNLLELDCHVT-GSPPPTIMWLKDGQLIDERDGFKIL--LNGRKLVIAQAQVSNTGLYR 1804
Query: 217 CVATNQMGSASCELTLSVTEPSQGRVAG 244
C+A N G E ++V P + +G
Sbjct: 1805 CMAANTAGDHKKEFEVTVHVPPTIKSSG 1832
Score = 34.3 bits (77), Expect = 0.16
Identities = 32/113 (28%), Positives = 50/113 (44%), Gaps = 20/113 (17%)
Query: 123 VNNPPDFYTNGLGLINLTVLVPPSNPLCSQSGQTSVGGSTALRCSSSEGAPKPVYNWVRL 182
V+ PP G ++N TVLV SNP+ L C ++ G P PV W +
Sbjct: 1915 VHEPPSLEDAGK-MLNETVLV--SNPV-------------QLECKAA-GNPVPVITWYKD 1957
Query: 183 GTFPTPSPGSMVQDEVSGQLI-LTNLSLTSSGTYRCVATNQMGSASCELTLSV 234
+ S + GQ+I + + ++ +G Y+CVA N G+ +L V
Sbjct: 1958 NRLLSGSTSMTFLNR--GQIIDIESAQISDAGIYKCVAINSAGATELFYSLQV 2008
Score = 29.3 bits (64), Expect = 5.0
Identities = 11/44 (25%), Positives = 23/44 (52%)
Query: 194 VQDEVSGQLILTNLSLTSSGTYRCVATNQMGSASCELTLSVTEP 237
+++ S L + ++L+ G Y C+A + G+ + V+EP
Sbjct: 476 LKESASVNLDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSEP 519
>gi|239755187 PREDICTED: similar to hemicentin 2 [Homo sapiens]
Length = 1215
Score = 60.5 bits (145), Expect = 2e-09
Identities = 62/213 (29%), Positives = 85/213 (39%), Gaps = 30/213 (14%)
Query: 45 CTYSTSVGDSFALEWSFVQPGKPISESHPILYFTNG---------HLYPTG--SKSKRVS 93
C S + G + A W V+ +S +F+ G YPT S S+
Sbjct: 470 CVASNANGVTRASVWLLVREAPQVSIHTSSQHFSQGVEVKVSCSASGYPTPHISWSRESQ 529
Query: 94 LLQNPPTVGV---ATLKLTDVHPSDTGTYLCQVNNPPDFYTNGLGLINLTVLV----PPS 146
LQ + V TL + V P D G Y CQ TN +G TV + PPS
Sbjct: 530 ALQEDSRIHVDAQGTLIIQGVAPEDAGNYSCQA-------TNEVGTDQETVTLYYTDPPS 582
Query: 147 NPLCSQSGQTSVGGSTALRCSSSEGAPKPVYNWVRLGTFPTPSPGSMVQDEVSGQLILTN 206
+ +VG L C +S G P P W R G +P + SG+L +
Sbjct: 583 VSAVNAVVLVAVGEEAVLVCEAS-GVPPPRVIWYRGGLEMILAP----EGSSSGKLRIPA 637
Query: 207 LSLTSSGTYRCVATNQMGSASCELTLSVTEPSQ 239
+GTY C A N++G AS E+ L+V Q
Sbjct: 638 AQERDAGTYTCRAVNELGDASAEIQLAVGHAPQ 670
Score = 56.6 bits (135), Expect = 3e-08
Identities = 41/150 (27%), Positives = 71/150 (47%), Gaps = 10/150 (6%)
Query: 105 TLKLTDVHPSDTGTYLCQVNNPPDFYTNGLGLINLTVLV--PPSNPLCSQSGQTSVGGST 162
+L+++ + P+D G Y C +N NG+ ++ +LV P + + S S G
Sbjct: 454 SLEISGIIPTDGGRYQCVASN-----ANGVTRASVWLLVREAPQVSIHTSSQHFSQGVEV 508
Query: 163 ALRCSSSEGAPKPVYNWVRLGTFPTPSPGSMVQDEVSGQLILTNLSLTSSGTYRCVATNQ 222
+ CS+S G P P +W R S + + G LI+ ++ +G Y C ATN+
Sbjct: 509 KVSCSAS-GYPTPHISWSRESQ--ALQEDSRIHVDAQGTLIIQGVAPEDAGNYSCQATNE 565
Query: 223 MGSASCELTLSVTEPSQGRVAGALIGVLLG 252
+G+ +TL T+P A++ V +G
Sbjct: 566 VGTDQETVTLYYTDPPSVSAVNAVVLVAVG 595
Score = 49.7 bits (117), Expect = 4e-06
Identities = 51/178 (28%), Positives = 70/178 (39%), Gaps = 20/178 (11%)
Query: 62 VQPGKPISESHPILYFTNGHLYPTGSK-SKRVSLLQNPPTVGVATLKLTDVHPSDTGTYL 120
V G+P+ E H + +G P GS+ S R +L L G Y
Sbjct: 791 VLAGRPLPERH---WLKDGRPLPPGSRHSIRAD----------GSLHLDRALQEHAGRYS 837
Query: 121 CQVNNPPDFYTNGLGLINLTVLVPPSNPLCSQSGQTSVGGSTALRCSSSEGAPKPVYNWV 180
C N + L V VPP + T+ G +L C +S G P P W
Sbjct: 838 CVATNTAGSQHRD---VELVVQVPPRIHPTATHHITNEGVPASLPCVAS-GVPAPTITWT 893
Query: 181 RLGTFPTPSPGSMVQDEVSGQLILTNLSLTSSGTYRCVATNQMGSASCELTLSV-TEP 237
+ T S G G L++ S +G Y C ATN +G +S E+ LSV T+P
Sbjct: 894 K-ETNALTSRGPHYNVSKEGTLLIAQPSAQDAGAYVCTATNTVGFSSQEMRLSVNTKP 950
Score = 44.7 bits (104), Expect = 1e-04
Identities = 39/143 (27%), Positives = 57/143 (39%), Gaps = 10/143 (6%)
Query: 105 TLKLTDVHPSDTGTYLCQVNNPPDFYTNGLGL-INLTVLVPPS---NPLCSQSGQTSVGG 160
TL + D G Y+C N F + + L +N + + N G
Sbjct: 913 TLLIAQPSAQDAGAYVCTATNTVGFSSQEMRLSVNTKPRIHMNGSRNANVPLQVTAKAGE 972
Query: 161 STALRCSSSEGAPKPVYNWVRLGTFPTPSPGSMVQDEVSGQLILTNLSLTSSGTYRCVAT 220
L C + +G+P P+ W + + P P + SG L L + + SG Y C A+
Sbjct: 973 EVTLDCEA-KGSPPPLVTWTK-DSRPVPPITNRYGLLPSGSLRLAQVQVGDSGHYECTAS 1030
Query: 221 NQMGSASCELTLSVTEPSQGRVA 243
N GSAS L V QGR +
Sbjct: 1031 NPAGSASHRYVLGV----QGRTS 1049
>gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 5065
Score = 60.5 bits (145), Expect = 2e-09
Identities = 62/213 (29%), Positives = 85/213 (39%), Gaps = 30/213 (14%)
Query: 45 CTYSTSVGDSFALEWSFVQPGKPISESHPILYFTNG---------HLYPTG--SKSKRVS 93
C S + G + A W V+ +S +F+ G YPT S S+
Sbjct: 587 CVASNANGVTRASVWLLVREAPQVSIHTSSQHFSQGVEVKVSCSASGYPTPHISWSRESQ 646
Query: 94 LLQNPPTVGV---ATLKLTDVHPSDTGTYLCQVNNPPDFYTNGLGLINLTVLV----PPS 146
LQ + V TL + V P D G Y CQ TN +G TV + PPS
Sbjct: 647 ALQEDSRIHVDAQGTLIIQGVAPEDAGNYSCQA-------TNEVGTDQETVTLYYTDPPS 699
Query: 147 NPLCSQSGQTSVGGSTALRCSSSEGAPKPVYNWVRLGTFPTPSPGSMVQDEVSGQLILTN 206
+ +VG L C +S G P P W R G +P + SG+L +
Sbjct: 700 VSAVNAVVLVAVGEEAVLVCEAS-GVPPPRVIWYRGGLEMILAP----EGSSSGKLRIPA 754
Query: 207 LSLTSSGTYRCVATNQMGSASCELTLSVTEPSQ 239
+GTY C A N++G AS E+ L+V Q
Sbjct: 755 AQERDAGTYTCRAVNELGDASAEIQLAVGHAPQ 787
Score = 57.8 bits (138), Expect = 1e-08
Identities = 60/192 (31%), Positives = 77/192 (40%), Gaps = 17/192 (8%)
Query: 62 VQPGKPI-----SESHPILYFTNGHLYPTGSKSKRVSLLQNPPTVGVATLKLTDVHPSDT 116
VQPG + E+ + G+ P S SK +LQ G ++ + SD
Sbjct: 1122 VQPGPRVLKVLVGEALDLNCVAEGNPEPQLSWSKDGVVLQGRGPQG--SVHFAAIRTSDA 1179
Query: 117 GTYLCQVNNPPDFYTNGLGLINLTVLVPPSNPLCSQSGQTS-VGGSTALRCSSSEGAPKP 175
G Y C+ +N + L VL PP SG V G A + G PKP
Sbjct: 1180 GRYRCEASNSAGV---DAWEVELRVLEPPHWGADETSGLLERVAGENASLPCPARGTPKP 1236
Query: 176 VYNWVRLGTFPTP---SPGSMVQDEVSGQLILTNLSLTSSGTYRCVATNQMGSASCELTL 232
W R G P PG V +E G L L ++S SG Y C ATN++GS S L
Sbjct: 1237 QVTW-RKGPSSEPLHGQPGVAVLEE--GSLFLASVSPADSGDYECQATNEVGSTSRRAKL 1293
Query: 233 SVTEPSQGRVAG 244
V P R G
Sbjct: 1294 VVYVPPSIREDG 1305
Score = 56.6 bits (135), Expect = 3e-08
Identities = 41/150 (27%), Positives = 71/150 (47%), Gaps = 10/150 (6%)
Query: 105 TLKLTDVHPSDTGTYLCQVNNPPDFYTNGLGLINLTVLV--PPSNPLCSQSGQTSVGGST 162
+L+++ + P+D G Y C +N NG+ ++ +LV P + + S S G
Sbjct: 571 SLEISGIIPTDGGRYQCVASN-----ANGVTRASVWLLVREAPQVSIHTSSQHFSQGVEV 625
Query: 163 ALRCSSSEGAPKPVYNWVRLGTFPTPSPGSMVQDEVSGQLILTNLSLTSSGTYRCVATNQ 222
+ CS+S G P P +W R S + + G LI+ ++ +G Y C ATN+
Sbjct: 626 KVSCSAS-GYPTPHISWSRESQ--ALQEDSRIHVDAQGTLIIQGVAPEDAGNYSCQATNE 682
Query: 223 MGSASCELTLSVTEPSQGRVAGALIGVLLG 252
+G+ +TL T+P A++ V +G
Sbjct: 683 VGTDQETVTLYYTDPPSVSAVNAVVLVAVG 712
Score = 56.2 bits (134), Expect = 4e-08
Identities = 38/129 (29%), Positives = 56/129 (43%), Gaps = 5/129 (3%)
Query: 106 LKLTDVHPSDTGTYLCQVNNPPDFYTNGLGLINLTVLVPPSNPLCSQSGQTSVGGSTALR 165
L++ P D G YLC N + +G L V VPP T+ G L
Sbjct: 4002 LRIAHASPEDAGNYLCIAKNSAG---SAMGKTRLVVQVPPVIENGLPDLSTTEGSHAFLP 4058
Query: 166 CSSSEGAPKPVYNWVRLGTFPTPSPGSMVQDEVSGQLILTNLSLTSSGTYRCVATNQMGS 225
C + G+P+P W + G P + SG+L++ NL +GTY C A N +G
Sbjct: 4059 CKA-RGSPEPNITWDKDGQ-PVSGAEGKFTIQPSGELLVKNLEGQDAGTYTCTAENAVGR 4116
Query: 226 ASCELTLSV 234
A + L++
Sbjct: 4117 ARRRVHLTI 4125
Score = 54.3 bits (129), Expect = 1e-07
Identities = 46/147 (31%), Positives = 64/147 (43%), Gaps = 12/147 (8%)
Query: 102 GVATLKLTDVHPSDTGTYLCQVNNPPDFYTNGLGLINLTVLVPPS--NPLCSQSGQTSVG 159
G L++ + SD G Y C+V+N + LTV VPP+ NP Q + G
Sbjct: 3084 GGQRLEIQEAQVSDKGLYSCKVSNVAG---EAVRTFTLTVQVPPTFENPKTETVSQVA-G 3139
Query: 160 GSTALRCSSSEGAPKPVYNWVRLGTFPTPSPGSMVQDEVS--GQLILTNLSLTSSGTYRC 217
L C S G P P W++ P S V VS G+L L+ L +GTY C
Sbjct: 3140 SPLVLTCDVS-GVPAPTVTWLK---DRMPVESSAVHGVVSRGGRLQLSRLQPAQAGTYTC 3195
Query: 218 VATNQMGSASCELTLSVTEPSQGRVAG 244
VA N A + ++V + R +G
Sbjct: 3196 VAENTQAEARKDFVVAVLVAPRIRSSG 3222
Score = 52.8 bits (125), Expect = 4e-07
Identities = 49/179 (27%), Positives = 85/179 (47%), Gaps = 14/179 (7%)
Query: 87 SKSKRVSLLQNPPTVGVATLKLTDVHPSDTGTYLCQVNNP--PDFYTNGLGLINLTVLVP 144
S VS+LQ G L++ V + G Y C+ +N D+ L ++ V++
Sbjct: 2792 SAGDEVSVLQ-----GGRVLQIPLVRAENAGRYSCKASNEVGEDWLHYELLVLTPPVILG 2846
Query: 145 PSNPLCSQSGQTSVGGSTALRCSSSEGAPKPVYNWVRLGTFPTPSPGSMVQDEVSGQLI- 203
+ L + + + +L+C + G P P +W++ G +PSP V ++ GQ++
Sbjct: 2847 DTEELVEEV-TVNASSTVSLQCPAL-GNPVPTISWLQNGLPFSPSPRLQVLED--GQVLQ 2902
Query: 204 LTNLSLTSSGTYRCVATNQMGSASCELTLSVTEPSQGRVAGALIGVLLGVLLLSVAAFC 262
++ + + +Y CVA NQ GSA TL V P R+AG + + +L SV+ C
Sbjct: 2903 VSTAEVADAASYMCVAENQAGSAEKLFTLRVQVPP--RIAGLDLEQVTAILNSSVSLPC 2959
Score = 50.1 bits (118), Expect = 3e-06
Identities = 47/152 (30%), Positives = 66/152 (43%), Gaps = 17/152 (11%)
Query: 115 DTGTYLCQVNNPPDFYTNGLGLIN-LTVLVPPSNPLCSQSGQTSV---GGSTALRCSSSE 170
D G Y C N +G+ + +LV S P+ Q G ALRC ++
Sbjct: 4282 DAGRYQCLAENE-------MGVAKKVVILVLQSAPVFQVEPQDMTVRSGDDVALRCQAT- 4333
Query: 171 GAPKPVYNWVRLGTFPTPSPGSMVQDEVSGQLILTNLSLTSSGTYRCVATNQMGSASCEL 230
G P P W++ G S ++ G L L N+ +GTY CVA N +GSA+
Sbjct: 4334 GEPTPTIEWLQAGQPLRAS--RRLRTLPDGSLWLENVETGDAGTYDCVAHNLLGSATARA 4391
Query: 231 TLSVT-EP--SQGRVAGALIGVLLGVLLLSVA 259
L V EP S G + G + G GV L+ +
Sbjct: 4392 FLVVRGEPQGSWGSMTGVINGRKFGVATLNTS 4423
Score = 49.7 bits (117), Expect = 4e-06
Identities = 51/190 (26%), Positives = 72/190 (37%), Gaps = 19/190 (10%)
Query: 62 VQPGKPISESHPILYFTNGHLYPTGSK-SKRVSLLQNPPTVGVATLKLTDVHPSDTGTYL 120
V G+P+ E H + +G P GS+ S R +L L G Y
Sbjct: 908 VLAGRPLPERH---WLKDGRPLPPGSRHSIRAD----------GSLHLDRALQEHAGRYS 954
Query: 121 CQVNNPPDFYTNGLGLINLTVLVPPSNPLCSQSGQTSVGGSTALRCSSSEGAPKPVYNWV 180
C N + L V VPP + T+ G +L C +S G P P W
Sbjct: 955 CVATNTAGSQHRD---VELVVQVPPRIHPTATHHITNEGVPASLPCVAS-GVPAPTITWT 1010
Query: 181 RLGTFPTPSPGSMVQDEVSGQLILTNLSLTSSGTYRCVATNQMGSASCELTLSVTEPSQG 240
+ T S G G L++ S +G Y C ATN +G +S E+ LSV +
Sbjct: 1011 K-ETNALTSRGPHYNVSKEGTLLIAQPSAQDAGAYVCTATNTVGFSSQEMRLSVNRLALS 1069
Query: 241 RVAGALIGVL 250
+ G+L
Sbjct: 1070 KYVWEEYGLL 1079
Score = 49.7 bits (117), Expect = 4e-06
Identities = 53/178 (29%), Positives = 73/178 (41%), Gaps = 20/178 (11%)
Query: 74 ILYFTNGHLYPTGSKSKRVSLLQNPPTVGVATLKLTDVHPSDTGTYLCQVNNPPDFYTNG 133
I +F +G L PT +K T G L+L SD G Y C+ +N
Sbjct: 1534 ITWFKDGALLPTSTKVVY--------TRGGRQLQLGRAQSSDAGVYTCKASNAVGAAEKA 1585
Query: 134 LGLINLTVLVPPSNPLCSQSGQTSV-----GGSTALRCSSSEGAPKPVYNWVRLGTFPTP 188
L V VPP+ + G+ V G AL C + G P P +W G
Sbjct: 1586 T---RLDVYVPPT--IEGAGGRPYVVKAVAGRPVALECVA-RGHPSPTLSWHHEGLPVAE 1639
Query: 189 SPGSMVQDEVSGQLILTNLSLTSSGTYRCVATNQMGSASCELTLSVTEPSQGRVAGAL 246
S S ++ + S L L + SSG Y CVA++ G A + ++ V P Q VA L
Sbjct: 1640 SNESRLETDGS-VLRLESPGEASSGLYSCVASSPAGEAVLQYSVEVQVPPQLLVAEGL 1696
Score = 48.9 bits (115), Expect = 6e-06
Identities = 38/133 (28%), Positives = 62/133 (46%), Gaps = 7/133 (5%)
Query: 104 ATLKLTDVHPSDTGTYLCQVNNPPDFYTNGLGLINLTVLVPPSNPLCSQSGQ--TSVGGS 161
+ L+L + +G Y C ++P + ++ V VPP + GQ T VG
Sbjct: 1650 SVLRLESPGEASSGLYSCVASSPAG---EAVLQYSVEVQVPPQLLVAEGLGQVTTIVGQP 1706
Query: 162 TALRCSSSEGAPKPVYNWVRLGTFPTPSPGSMVQDEVSGQLILTNLSLTSSGTYRCVATN 221
L C +S G+P P W++ G G V + + L + ++ L SG + C ATN
Sbjct: 1707 LELPCQAS-GSPVPTIQWLQNGRPAEELAGVQVASQGT-TLHIDHVELDHSGLFACQATN 1764
Query: 222 QMGSASCELTLSV 234
+ G+A E+ +SV
Sbjct: 1765 EAGTAGAEVEVSV 1777
Score = 48.9 bits (115), Expect = 6e-06
Identities = 39/134 (29%), Positives = 56/134 (41%), Gaps = 9/134 (6%)
Query: 105 TLKLTDVHPSDTGTYLCQVNNPPDFYTNGLGLINLTVLVPPS-NPLCSQSGQTSVGGSTA 163
TL+++ V +D G + C +P L V VPP P+ Q+ V GS
Sbjct: 3368 TLRISKVQLADAGIFTCVAASPAGVADRNF---TLQVQVPPVLEPVEFQNDVVVVRGSLV 3424
Query: 164 LRCSSSEGAPKPVYNWVRLGTFPTPSPGSMVQDEVSGQLILTNLSLTSSGTYRCVATNQM 223
+ G P P+ +W++ G P E L L + SGTY CVA ++
Sbjct: 3425 ELPCEARGVPLPLVSWMKDG-----EPLLSQSLEQGPSLQLEAVGAGDSGTYSCVAVSEA 3479
Query: 224 GSASCELTLSVTEP 237
G A L+V EP
Sbjct: 3480 GEARRHFQLTVMEP 3493
Score = 48.1 bits (113), Expect = 1e-05
Identities = 42/128 (32%), Positives = 53/128 (41%), Gaps = 8/128 (6%)
Query: 115 DTGTYLCQVNNPPDFYTNGLGLINLTVLVPPSNPLCSQSGQT-SVGGSTALRCSSSEGAP 173
D G Y C+ N NL V V P PL T G T+L C G P
Sbjct: 2135 DAGHYTCEALNQAGHSEKHY---NLNVWVAPVFPLRESHTLTVREGHPTSLSCEC-RGVP 2190
Query: 174 KPVYNWVRLGTFPTPSPGSMVQ--DEVSGQLILTNLSLTSSGTYRCVATNQMGSASCELT 231
P +W + G P P G+ +Q V L L L GTY C +N +G++S +L
Sbjct: 2191 FPKISWRKDGQ-PLPGEGAGLQHVSAVGRLLYLGQAQLAQEGTYTCECSNVVGNSSQDLQ 2249
Query: 232 LSVTEPSQ 239
L V P Q
Sbjct: 2250 LEVHVPPQ 2257
Score = 48.1 bits (113), Expect = 1e-05
Identities = 47/164 (28%), Positives = 70/164 (42%), Gaps = 19/164 (11%)
Query: 89 SKRVSLLQNPPTVGVATLKLTDVHPSDTGTYLCQVNNPPDFYTNGLGLINLTVLVPPS-- 146
S+ + LL P T G L++ + D G Y C V N + ++ VL+PPS
Sbjct: 2585 SRNIQLL--PGTHG---LQILNAQKEDAGQYTCVVTNE---LGEAVKNYHVEVLIPPSIS 2636
Query: 147 --NPLCS---QSGQTSVGGSTALRCSSSEGAPKPVYNWVRLGTFPTPSPGSMVQDEVSGQ 201
+PL + +T V + L C S P P W + G TPS V E G+
Sbjct: 2637 KDDPLGEVGVKEVKTKVNSTLTLECESW-AVPPPTIRWYKDGQPVTPSSRLQVLGE--GR 2693
Query: 202 LI-LTNLSLTSSGTYRCVATNQMGSASCELTLSVTEPSQGRVAG 244
L+ + ++ SG Y CVATN G + + + P + G
Sbjct: 2694 LLQIQPTQVSDSGRYLCVATNVAGEDDQDFNVLIQVPPMFQKVG 2737
Score = 47.8 bits (112), Expect = 1e-05
Identities = 38/136 (27%), Positives = 63/136 (46%), Gaps = 10/136 (7%)
Query: 106 LKLTDVHPSDTGTYLCQVNNPPDFYTNGLGL-INLT--VLVPPSNPLCSQSGQTSVGGST 162
L++ SD G+Y C +N GL +N+ + +PPS P G V
Sbjct: 1941 LRIEQAQLSDAGSYRCVASNVAGSTELRYGLRVNVPPRITLPPSLP-----GPVLVNTPV 1995
Query: 163 ALRCSSSEGAPKPVYNWVRLGTFPTPSPGSMVQDEVSGQLI-LTNLSLTSSGTYRCVATN 221
L C+++ GAP P W++ G +P+ +Q G+++ L + + SG Y CVA +
Sbjct: 1996 RLTCNAT-GAPSPTLMWLKDGNPVSPAGTPGLQVFPGGRVLTLASARASDSGRYSCVAVS 2054
Query: 222 QMGSASCELTLSVTEP 237
+G ++ L V P
Sbjct: 2055 AVGEDRQDVVLQVHMP 2070
Score = 47.4 bits (111), Expect = 2e-05
Identities = 52/211 (24%), Positives = 79/211 (37%), Gaps = 14/211 (6%)
Query: 106 LKLTDVHPSDTGTYLCQVNNPPDFYTNGLGLINLTVLVPPSNPLCSQSGQTSVGGSTALR 165
L++T H D G Y C +P L V PP+ +++G+ +V ++
Sbjct: 1465 LRITGSHVGDEGRYQCVAFSPAGQQARDF---QLRVHAPPTIWGSNETGEVAVMEDHLVQ 1521
Query: 166 C-SSSEGAPKPVYNWVRLGTFPTPSPGSMVQDEVSGQLILTNLSLTSSGTYRCVATNQMG 224
+ G P P W + G P+ +V QL L + +G Y C A+N +G
Sbjct: 1522 LLCEARGVPTPNITWFKDGAL-LPTSTKVVYTRGGRQLQLGRAQSSDAGVYTCKASNAVG 1580
Query: 225 SASCELTLSVTEPSQGRVAGALIGVLLGVLLLSVAAFCLVRFQKERGKKPKETYGGSDLR 284
+A L V P AG V+ V VA C+ R P T
Sbjct: 1581 AAEKATRLDVYVPPTIEGAGGRPYVVKAVAGRPVALECVAR------GHPSPTL---SWH 1631
Query: 285 EDAIAPGISEHTCMRADSSKGFLERPSSAST 315
+ + S + + D S LE P AS+
Sbjct: 1632 HEGLPVAESNESRLETDGSVLRLESPGEASS 1662
Score = 46.2 bits (108), Expect = 4e-05
Identities = 38/134 (28%), Positives = 60/134 (44%), Gaps = 13/134 (9%)
Query: 105 TLKLTDVHPSDTGTYLCQVNNPPDFYTNGLGLINLTVLVPPSNPLCSQSGQTSVGGSTAL 164
+L+L V D+G Y C +NP ++ L V VPP + + VG + L
Sbjct: 1083 SLRLAQVQVGDSGHYECTASNPAGSASH---RYVLGVQVPPQVQPGPRVLKVLVGEALDL 1139
Query: 165 RCSSSEGAPKPVYNWVRLGTFPTPSPGSMVQDE-VSGQLILTNLSLTSSGTYRCVATNQM 223
C +EG P+P +W + G ++Q G + + + +G YRC A+N
Sbjct: 1140 NC-VAEGNPEPQLSWSK--------DGVVLQGRGPQGSVHFAAIRTSDAGRYRCEASNSA 1190
Query: 224 GSASCELTLSVTEP 237
G + E+ L V EP
Sbjct: 1191 GVDAWEVELRVLEP 1204
Score = 46.2 bits (108), Expect = 4e-05
Identities = 41/146 (28%), Positives = 59/146 (40%), Gaps = 5/146 (3%)
Query: 106 LKLTDVHPSDTGTYLCQVNNPPDFYTNGLGLINLTVLVPPSNPLCSQSGQTSVGGSTALR 165
L++ V D G Y C N + L VLVPP+ + S L
Sbjct: 1850 LQIEKVDLRDEGIYTCAATN---LAGESKREVALKVLVPPNIEPGPVNKAVLENASVTLE 1906
Query: 166 CSSSEGAPKPVYNWVRLGTFPTPSPGSMVQDEVSGQLILTNLSLTSSGTYRCVATNQMGS 225
C +S G P P +W + G P S + L + L+ +G+YRCVA+N GS
Sbjct: 1907 CLAS-GVPPPDVSWFK-GHQPVSSWMGVTVSVDGRVLRIEQAQLSDAGSYRCVASNVAGS 1964
Query: 226 ASCELTLSVTEPSQGRVAGALIGVLL 251
L V P + + +L G +L
Sbjct: 1965 TELRYGLRVNVPPRITLPPSLPGPVL 1990
Score = 44.3 bits (103), Expect = 2e-04
Identities = 39/132 (29%), Positives = 58/132 (43%), Gaps = 9/132 (6%)
Query: 106 LKLTDVHPSDTGTYLCQVNNPPDFYTNGLGLINLTVLVPPS--NPLCSQSGQTSVGGSTA 163
LK+T D+G Y C +N ++ VLVPPS N + + G +
Sbjct: 2408 LKMTQTQEQDSGLYSCLASNEAGEARRNF---SVEVLVPPSIENEDLEEVIKVLDGQTAH 2464
Query: 164 LRCSSSEGAPKPVYNWVRLGTFPTPSPGSMVQ-DEVSGQLILTNLSLTSSGTYRCVATNQ 222
L C+ + G P+P W + G + D V Q++ NLS S+G Y C+A N
Sbjct: 2465 LMCNVT-GHPQPKLTWFKDGRPLARGDAHHISPDGVLLQVLQANLS--SAGHYSCIAANA 2521
Query: 223 MGSASCELTLSV 234
+G + LSV
Sbjct: 2522 VGEKTKHFQLSV 2533
Score = 44.3 bits (103), Expect = 2e-04
Identities = 43/150 (28%), Positives = 67/150 (44%), Gaps = 15/150 (10%)
Query: 86 GSKSKRVSLLQN--PPTVGVA------TLKLTDVHPSDTGTYLCQVNNPPDFYTNGLGLI 137
GS + R+ N P T GV+ TL+ V D+GTY+C N T + +
Sbjct: 4154 GSPTPRIGWTVNDRPVTEGVSEQDGGSTLQRAAVSREDSGTYVCWAENRVG-RTQAVSFV 4212
Query: 138 NLTVLVPPSNPLCSQSGQTSVGGSTALRCSSSEGAPKPVYNWVRLGTFPTPSPGSMVQDE 197
++ S + VGGS L C G P P +W++ G P GS ++ +
Sbjct: 4213 HVKEAPVLQGEAFSYLVEP-VGGSIQLDCVV-RGDPVPDIHWIKDGL---PLRGSHLRHQ 4267
Query: 198 V-SGQLILTNLSLTSSGTYRCVATNQMGSA 226
+ +G L + +G Y+C+A N+MG A
Sbjct: 4268 LQNGSLTIHRTERDDAGRYQCLAENEMGVA 4297
Score = 43.9 bits (102), Expect = 2e-04
Identities = 36/135 (26%), Positives = 53/135 (39%), Gaps = 6/135 (4%)
Query: 105 TLKLTDVHPSDTGTYLCQVNNPPDFYTNGLGLINLTVLVPPSNPLCSQSGQTSVG--GST 162
+L L + SD G Y C +NP L + VLVPP+ + T V G
Sbjct: 3274 SLVLKGLRASDAGAYTCVAHNPAG---EDARLHTVNVLVPPTIKQGADGSGTLVSRPGEL 3330
Query: 163 ALRCSSSEGAPKPVYNWVRLGTFPTPSPGSMVQDEVSGQLILTNLSLTSSGTYRCVATNQ 222
G+P +W++ G P P + L ++ + L +G + CVA +
Sbjct: 3331 VTMVCPVRGSPPIHVSWLKDG-LPLPLSQRTLLHGSGHTLRISKVQLADAGIFTCVAASP 3389
Query: 223 MGSASCELTLSVTEP 237
G A TL V P
Sbjct: 3390 AGVADRNFTLQVQVP 3404
Score = 43.5 bits (101), Expect = 3e-04
Identities = 52/175 (29%), Positives = 68/175 (38%), Gaps = 23/175 (13%)
Query: 95 LQNPPTVGV---ATLKLTDVHPSDTGTYLCQVNNPPDFYTNGLGLINLTVLVPPSNPLCS 151
L P V V +L L V P+D+G Y CQ N + L+ V VPPS
Sbjct: 1249 LHGQPGVAVLEEGSLFLASVSPADSGDYECQATNEVGSTSRRAKLV---VYVPPSIREDG 1305
Query: 152 QSGQTS--VGGSTALRCSSSEGAPKPVYNWVR---LGTFPTPSPG---SMVQDEVSGQLI 203
+ S G S L C ++ G P P W++ L P G + +V G +
Sbjct: 1306 RKANVSGMAGQSLTLECDAN-GFPVPEIVWLKDAQLVGVPLGWAGYGWDLGWGQVGGHRL 1364
Query: 204 LTN--------LSLTSSGTYRCVATNQMGSASCELTLSVTEPSQGRVAGALIGVL 250
L + SG Y C A NQ G+A + L V P AGA VL
Sbjct: 1365 LDEGQSLHFPRIQEGDSGLYSCRAENQAGTAQRDFHLLVLTPPSVLGAGAAQEVL 1419
Score = 42.0 bits (97), Expect = 7e-04
Identities = 47/150 (31%), Positives = 63/150 (42%), Gaps = 13/150 (8%)
Query: 95 LQNPPTVGVATLKLTDVHPSDTGTYLCQVNNPPDFYTNGLGLINLTVLVPP--SNPLCSQ 152
LQ+ VG L L + GTY C+ +N N + L V VPP + P
Sbjct: 2210 LQHVSAVG-RLLYLGQAQLAQEGTYTCECSN---VVGNSSQDLQLEVHVPPQIAGPR-EP 2264
Query: 153 SGQTSV--GGSTALRCSSSEGAPKPVYNWVRLGTFPTPSPGSMVQDEVSGQ-LILTNLSL 209
Q SV G L C+++ G P P W R G G +Q++ GQ L +
Sbjct: 2265 PTQVSVVQDGVATLECNAT-GKPPPTVTWERDGQPVGAELGLQLQNQ--GQSLHVERAQA 2321
Query: 210 TSSGTYRCVATNQMGSASCELTLSVTEPSQ 239
+G Y CVA N G A + LSV P +
Sbjct: 2322 AHTGRYSCVAENLAGRAERKFELSVLVPPE 2351
Score = 40.0 bits (92), Expect = 0.003
Identities = 41/162 (25%), Positives = 62/162 (38%), Gaps = 13/162 (8%)
Query: 106 LKLTDVHPSDTGTYLCQVNNPPDFYTNGLGLINLTVLVPPSNPLCSQSGQTSVGGSTALR 165
L + ++ D GTY C N ++LT+LV P +G LR
Sbjct: 4093 LLVKNLEGQDAGTYTCTAENAVG---RARRRVHLTILVLPVFTTLPGDRSLRLGDRLWLR 4149
Query: 166 CSSSEGAPKPVYNWVRLGTFPTPSPGSMVQDEVSGQLILTNLSLTSSGTYRCVATNQMGS 225
C++ G+P P W P + + + L +S SGTY C A N++G
Sbjct: 4150 CAA-RGSPTPRIGWT---VNDRPVTEGVSEQDGGSTLQRAAVSREDSGTYVCWAENRVGR 4205
Query: 226 ASCELTLSVTEPS--QGRVAGALIGVLLGVLLLSVAAFCLVR 265
+ V E QG L+ + G S+ C+VR
Sbjct: 4206 TQAVSFVHVKEAPVLQGEAFSYLVEPVGG----SIQLDCVVR 4243
Score = 39.7 bits (91), Expect = 0.004
Identities = 38/140 (27%), Positives = 59/140 (42%), Gaps = 17/140 (12%)
Query: 106 LKLTDVHPSDTGTYLCQVNNPP-----DFYTNGLGLINLTVLVPPSNPLCSQSGQTSV-- 158
L+L+ + P+ GTY C N DF + VLV P + + V
Sbjct: 3180 LQLSRLQPAQAGTYTCVAENTQAEARKDFV--------VAVLVAPRIRSSGVAREHHVLE 3231
Query: 159 GGSTALRCSSSEGAPKPVYNWVRLGTFPTPSPGSMVQDEVSG-QLILTNLSLTSSGTYRC 217
G L C + +G P P W++ G+ G ++ + G L+L L + +G Y C
Sbjct: 3232 GQEVRLDCEA-DGQPPPDVAWLKDGSPLGQDMGPHLRFYLDGGSLVLKGLRASDAGAYTC 3290
Query: 218 VATNQMGSASCELTLSVTEP 237
VA N G + T++V P
Sbjct: 3291 VAHNPAGEDARLHTVNVLVP 3310
Score = 39.7 bits (91), Expect = 0.004
Identities = 35/133 (26%), Positives = 52/133 (39%), Gaps = 8/133 (6%)
Query: 106 LKLTDVHPSDTGTYLCQVNNPPDFYTNGLGL-INLTVLVPPSNPLCSQSGQTSVGGSTAL 164
L++ P G Y C N + L + + +V P + + V L
Sbjct: 3912 LEIGQALPIHAGRYTCSARNSAGVAHKHVFLTVQASPVVKPLPSVVRAVAEEEV----LL 3967
Query: 165 RCSSSEGAPKPVYNWVRLGTFPTPSPGSMVQDEVSGQLILTNLSLTSSGTYRCVATNQMG 224
C +S G P+P W + G + G Q GQL + + S +G Y C+A N G
Sbjct: 3968 PCEAS-GIPRPTITWQKEGL--NVATGVSTQVLPGGQLRIAHASPEDAGNYLCIAKNSAG 4024
Query: 225 SASCELTLSVTEP 237
SA + L V P
Sbjct: 4025 SAMGKTRLVVQVP 4037
Score = 38.9 bits (89), Expect = 0.006
Identities = 26/79 (32%), Positives = 33/79 (41%), Gaps = 12/79 (15%)
Query: 177 YNWVRLGTFPTPSPGSMVQDEVSGQLILTNLSLTSSGTYRCVATNQMGSASCELTLSVTE 236
Y W G P SG L L + + SG Y C A+N GSAS L V
Sbjct: 1071 YVWEEYGLLP------------SGSLRLAQVQVGDSGHYECTASNPAGSASHRYVLGVQV 1118
Query: 237 PSQGRVAGALIGVLLGVLL 255
P Q + ++ VL+G L
Sbjct: 1119 PPQVQPGPRVLKVLVGEAL 1137
Score = 38.9 bits (89), Expect = 0.006
Identities = 40/146 (27%), Positives = 59/146 (40%), Gaps = 15/146 (10%)
Query: 84 PTGSKSKRVSLLQNPPTVGVATLKLTDVHPSDTGTYLCQVNNPPDFYTNGLGLINLTVLV 143
P +S R +L +L++ V D G YLC +N G +L VL
Sbjct: 3712 PLDPRSPRFEILPE------GSLRIQPVLAQDAGHYLCLASNSAGSDRQGR---DLRVLE 3762
Query: 144 PPSNPLCSQSGQTSVGGSTALRCSSSEGAPKPVYNWVRLGT---FPTPSPGSMVQDEVSG 200
PP+ S S T + AL + G+PKP+ W + G F + S
Sbjct: 3763 PPAIAP-SPSNLTLTAHTPALLPCEASGSPKPLVVWWKDGQKLDFRLQQGAYRLLP--SN 3819
Query: 201 QLILTNLSLTSSGTYRCVATNQMGSA 226
L+LT S + CV +N++G A
Sbjct: 3820 ALLLTAPGPQDSAQFECVVSNEVGEA 3845
Score = 38.5 bits (88), Expect = 0.008
Identities = 36/129 (27%), Positives = 52/129 (40%), Gaps = 5/129 (3%)
Query: 106 LKLTDVHPSDTGTYLCQVNNPPDFYTNGLGLINLTVLVPPSNPLCSQSGQTSVGGSTALR 165
L LT P D+ + C V+N L +TV VPP+ ++ L
Sbjct: 3821 LLLTAPGPQDSAQFECVVSNEVG---EAHRLYQVTVHVPPTIADDQTDFTVTMMAPVVLT 3877
Query: 166 CSSSEGAPKPVYNWVRLGTFPTPSPGSMVQDEVSGQLILTNLSLTSSGTYRCVATNQMGS 225
C S+ G P P +W + G + GS + SG L + +G Y C A N G
Sbjct: 3878 CHST-GIPAPTVSWSKAGA-QLGARGSGYRVSPSGALEIGQALPIHAGRYTCSARNSAGV 3935
Query: 226 ASCELTLSV 234
A + L+V
Sbjct: 3936 AHKHVFLTV 3944
Score = 38.1 bits (87), Expect = 0.011
Identities = 38/139 (27%), Positives = 56/139 (40%), Gaps = 14/139 (10%)
Query: 105 TLKLTDVHPSDTGTYLCQVNNPPDFYTNGLGLINLTVLVPPS-----NPLCSQSGQTSVG 159
+L + + TG Y C N L+VLVPP +PL + + ++
Sbjct: 2313 SLHVERAQAAHTGRYSCVAEN---LAGRAERKFELSVLVPPELIGDLDPLTNITA--ALH 2367
Query: 160 GSTALRCSSSEGAPKPVYNWVRLGTFPTPSPGSMVQDEVSGQLI-LTNLSLTSSGTYRCV 218
L C + G P P W R G P SPG G ++ +T SG Y C+
Sbjct: 2368 SPLTLLCEAM-GIPPPAIRWFR-GEEPV-SPGEDTYLLAGGWMLKMTQTQEQDSGLYSCL 2424
Query: 219 ATNQMGSASCELTLSVTEP 237
A+N+ G A ++ V P
Sbjct: 2425 ASNEAGEARRNFSVEVLVP 2443
Score = 37.4 bits (85), Expect = 0.018
Identities = 38/135 (28%), Positives = 53/135 (39%), Gaps = 9/135 (6%)
Query: 102 GVATLKLTDVHPSDTGTYLCQVNNPPDFYTNGLGLINLTVLVPPSNPLCSQSGQTSV--G 159
G L L SD+G Y C + + L V +PPS + + SV
Sbjct: 2031 GGRVLTLASARASDSGRYSCVAVSAVGEDRQD---VVLQVHMPPS--ILGEELNVSVVAN 2085
Query: 160 GSTALRCSSSEGAPKPVYNWVRLGTFPTPSPGSMVQDEVSGQLILTNLSLTSSGTYRCVA 219
S AL C S P PV +W + G P PG + + L + + +G Y C A
Sbjct: 2086 ESVALECQS-HAMPPPVLSWWKDGRPLEPRPGVHLSAD-KALLQVDRADVWDAGHYTCEA 2143
Query: 220 TNQMGSASCELTLSV 234
NQ G + L+V
Sbjct: 2144 LNQAGHSEKHYNLNV 2158
Score = 37.4 bits (85), Expect = 0.018
Identities = 56/227 (24%), Positives = 88/227 (38%), Gaps = 29/227 (12%)
Query: 22 LAVEVKVPTEPLSTPLGKTAELTCTYSTSVGDSFALEWSFVQPGKPISESHPILYFTNGH 81
L E+ V T P+ LG T EL + + + +L+ + G P+ I + NG
Sbjct: 2832 LHYELLVLTPPVI--LGDTEELVEEVTVNASSTVSLQCPAL--GNPVPT---ISWLQNGL 2884
Query: 82 LYPTGSKSKRVSLLQNPPTVGVATLKLTDVHPSDTGTYLCQVNNPPDFYTNGLGLINLTV 141
+ S S R+ +L++ + V+T ++ +D +Y+C N + L L V
Sbjct: 2885 PF---SPSPRLQVLEDGQVLQVSTAEV-----ADAASYMCVAENQAG---SAEKLFTLRV 2933
Query: 142 LVPPSNPLCSQSGQTSVGGSTALRCSSSEGAPKPVYNWVRLGTFPTPSPGSMVQDEV--- 198
VPP T++ S+ P P W + S + +EV
Sbjct: 2934 QVPPRIAGLDLEQVTAILNSSVSLPCDVHAHPNPEVTWYK------DSQALSLGEEVFLL 2987
Query: 199 --SGQLILTNLSLTSSGTYRCVATNQMGSASCELTLSVTEPSQGRVA 243
+ L L L+ SG Y C A N G + LSV P R A
Sbjct: 2988 PGTHTLQLGRARLSDSGMYTCEALNAAGRDQKLVQLSVLVPPAFRQA 3034
Score = 37.0 bits (84), Expect = 0.024
Identities = 35/135 (25%), Positives = 53/135 (39%), Gaps = 11/135 (8%)
Query: 106 LKLTDVHPSDTGTYLCQVNNPPDFYTNGLGLINLTVLVPPSNPLCSQSGQTSVGGS---T 162
L+L + +D+G Y C N G ++ V +SG +V S T
Sbjct: 3637 LQLQALSTADSGDYSCTARN-------AAGSTSVAFRVEIHTVPTIRSGPPAVNVSVNQT 3689
Query: 163 ALRCSSSEGAPKPVYNWVRLGTFPTPSPGSMVQDEVSGQLILTNLSLTSSGTYRCVATNQ 222
AL ++G P P+ +W R P + G L + + +G Y C+A+N
Sbjct: 3690 ALLPCQADGVPAPLVSW-RKDRVPLDPRSPRFEILPEGSLRIQPVLAQDAGHYLCLASNS 3748
Query: 223 MGSASCELTLSVTEP 237
GS L V EP
Sbjct: 3749 AGSDRQGRDLRVLEP 3763
Score = 34.3 bits (77), Expect = 0.16
Identities = 36/130 (27%), Positives = 47/130 (36%), Gaps = 23/130 (17%)
Query: 115 DTGTYLCQVNNPPDFYTNGLGLINLTVLVPPSNPLCSQSGQTSVG---GSTALRCSSSEG 171
D G Y C +P + V PP N + + + VG G L CS E
Sbjct: 3553 DAGLYTCLAESPAGAIEKSF---RVRVQAPP-NIVGPRGPRFVVGLAPGQLVLECSV-EA 3607
Query: 172 APKPVYNWVRLGTFPTPSPGSMVQDEVSGQ-------LILTNLSLTSSGTYRCVATNQMG 224
P P W R G ++Q++ Q L L LS SG Y C A N G
Sbjct: 3608 EPAPKITWHR--------DGIVLQEDAHTQFPERGRFLQLQALSTADSGDYSCTARNAAG 3659
Query: 225 SASCELTLSV 234
S S + +
Sbjct: 3660 STSVAFRVEI 3669
Score = 32.0 bits (71), Expect = 0.77
Identities = 21/67 (31%), Positives = 27/67 (40%), Gaps = 2/67 (2%)
Query: 173 PKP--VYNWVRLGTFPTPSPGSMVQDEVSGQLILTNLSLTSSGTYRCVATNQMGSASCEL 230
PKP V W G+ G V + L + + L G Y C ATN G + E+
Sbjct: 1819 PKPPLVEGWCSPGSLWGEPTGIPVAYSLPPPLQIEKVDLRDEGIYTCAATNLAGESKREV 1878
Query: 231 TLSVTEP 237
L V P
Sbjct: 1879 ALKVLVP 1885
Score = 30.0 bits (66), Expect = 2.9
Identities = 31/126 (24%), Positives = 47/126 (37%), Gaps = 10/126 (7%)
Query: 106 LKLTDVHPSDTGTYLCQVNNPPDFYTNGLGLINLTVLVPPS-----NPLCSQSGQTSVGG 160
L++ + S G Y C N T L+VL+ P+ + +V
Sbjct: 2501 LQVLQANLSSAGHYSCIAANAVGEKTKHF---QLSVLLAPTILGGAEDSADEEVTVTVNN 2557
Query: 161 STALRCSSSEGAPKPVYNWVRLGTFPTPSPGSMVQDEVSGQLILTNLSLTSSGTYRCVAT 220
+L C + P P W++ G S + G IL N +G Y CV T
Sbjct: 2558 PISLICEAL-AFPSPNITWMKDGAPFEASRNIQLLPGTHGLQIL-NAQKEDAGQYTCVVT 2615
Query: 221 NQMGSA 226
N++G A
Sbjct: 2616 NELGEA 2621
>gi|5901908 butyrophilin, subfamily 3, member A3 isoform a [Homo
sapiens]
Length = 584
Score = 60.5 bits (145), Expect = 2e-09
Identities = 68/274 (24%), Positives = 114/274 (41%), Gaps = 34/274 (12%)
Query: 29 PTEPLSTPLGKTAELTC-TYSTSVGDSFALEW---------SFVQPGKPISESHPILYFT 78
P+ P+ +G+ A+L C + T ++ L W + GK + + Y
Sbjct: 36 PSGPILAMVGEDADLPCHLFPTMSAETMELRWVSSSLRQVVNVYADGKEVEDRQSAPY-- 93
Query: 79 NGHLYPTGSKSKRVSLLQNPPTVGVATLKLTDVHPSDTGTYLCQVNNPPDFYTNGLGLIN 138
R S+L++ T G A L++ +V SD+G YLC + DFY L+
Sbjct: 94 ----------RGRTSILRDGITAGKAALRIHNVTASDSGKYLCYFQD-GDFYEK--ALVE 140
Query: 139 LTVLVPPSNPLCSQSGQTSVGGSTALRCSSSEGAPKPVYNWVRLGTFPTPS-PGSMVQDE 197
L V S+ G G L C S+ P+P W P+ +V D
Sbjct: 141 LKVAALGSDLHIEVKGYED--GGIHLECRSTGWYPQPQIKWSDTKGENIPAVEAPVVADG 198
Query: 198 VSGQLILTNLSL--TSSGTYRCVATNQMGSASCELTLSVTEP---SQGRVAGALIGVL-L 251
V + ++ + +S G C+ N + ++S+ +P S AL G L +
Sbjct: 199 VGLYAVAASVIMRGSSGGGVSCIIRNSLLGLEKTASISIADPFFRSAQPWIAALAGTLPI 258
Query: 252 GVLLLSVAAFCLVRFQKERGKKPKETYGGSDLRE 285
+LLL+ A++ L R QKE+ +ET +++E
Sbjct: 259 SLLLLAGASYFLWRQQKEKIALSRETEREREMKE 292
>gi|67188443 CD276 antigen isoform a [Homo sapiens]
Length = 534
Score = 60.1 bits (144), Expect = 3e-09
Identities = 64/239 (26%), Positives = 107/239 (44%), Gaps = 29/239 (12%)
Query: 11 GALLGFL--CLSGLAVEVKVPTEPLSTPLGKTAELTCTYSTSVGDSFA---LEWSFVQPG 65
GA LG L CL+G A+EV+VP +P+ +G A L C++S G S A L W
Sbjct: 15 GAALGALWFCLTG-ALEVQVPEDPVVALVGTDATLCCSFSPEPGFSLAQLNLIWQLTDTK 73
Query: 66 KPISESHPILYFTNGHLYPTGSK-SKRVSLLQNPPTVGVATLKLTDVHPSDTGTYLCQVN 124
+ + F G GS + R +L + G A+L+L V +D G++ C V
Sbjct: 74 QLVHS------FAEGQ--DQGSAYANRTALFPDLLAQGNASLRLQRVRVADEGSFTCFV- 124
Query: 125 NPPDFYTNGLGLINLTVLVPPSNPLCSQSGQTSV--GGSTALRCSSSEGAPKPVYNWVRL 182
+ DF G ++L V P S P + + G + + CSS +G P+ W
Sbjct: 125 SIRDF---GSAAVSLQVAAPYSKPSMTLEPNKDLRPGDTVTITCSSYQGYPEAEVFW--Q 179
Query: 183 GTFPTPSPGSMVQDEVSGQLILTNLS------LTSSGTYRCVATNQMGSASCELTLSVT 235
P G++ +++ + L ++ L ++GTY C+ N + ++++T
Sbjct: 180 DGQGVPLTGNVTTSQMANEQGLFDVHSILRVVLGANGTYSCLVRNPVLQQDAHSSVTIT 238
Score = 58.9 bits (141), Expect = 6e-09
Identities = 69/274 (25%), Positives = 118/274 (43%), Gaps = 28/274 (10%)
Query: 23 AVEVKVPTEPLSTPLGKTAELTCTYSTSVGDSFA---LEWSFVQPGKPISESHPILYFTN 79
AVEV+VP +P+ +G A L C++S G S A L W + + FT
Sbjct: 246 AVEVQVPEDPVVALVGTDATLRCSFSPEPGFSLAQLNLIWQLTDTKQLVHS------FTE 299
Query: 80 GHLYPTGSK-SKRVSLLQNPPTVGVATLKLTDVHPSDTGTYLCQVNNPPDFYTNGLGLIN 138
G GS + R +L + G A+L+L V +D G++ C V + DF G ++
Sbjct: 300 GR--DQGSAYANRTALFPDLLAQGNASLRLQRVRVADEGSFTCFV-SIRDF---GSAAVS 353
Query: 139 LTVLVPPSNPLCSQSGQTSV--GGSTALRCSSSEGAPKPVYNWVRLGTFPTPSPGSMVQD 196
L V P S P + + G + + CSS G P+ W P G++
Sbjct: 354 LQVAAPYSKPSMTLEPNKDLRPGDTVTITCSSYRGYPEAEVFW--QDGQGVPLTGNVTTS 411
Query: 197 EVSGQLILTNLS------LTSSGTYRCVATNQMGSASCELTLSVT-EPSQGRVAGALIGV 249
+++ + L ++ L ++GTY C+ N + ++++T +P + V
Sbjct: 412 QMANEQGLFDVHSVLRVVLGANGTYSCLVRNPVLQQDAHGSVTITGQPMTFPPEALWVTV 471
Query: 250 LLGVLLLS-VAAFCLVRFQKERGKKPKETYGGSD 282
L V L++ + A V ++K + +E G D
Sbjct: 472 GLSVCLIALLVALAFVCWRKIKQSCEEENAGAED 505
>gi|239743951 PREDICTED: hypothetical protein XP_002342997 [Homo
sapiens]
Length = 790
Score = 60.1 bits (144), Expect = 3e-09
Identities = 61/208 (29%), Positives = 84/208 (40%), Gaps = 30/208 (14%)
Query: 45 CTYSTSVGDSFALEWSFVQPGKPISESHPILYFTNG---------HLYPTG--SKSKRVS 93
C S + G + A W V+ +S +F+ G YPT S S+
Sbjct: 586 CVASNANGVTRASVWLLVREAPQVSIHTSSQHFSQGVEVKVSCSASGYPTPHISWSRESQ 645
Query: 94 LLQNPPTVGV---ATLKLTDVHPSDTGTYLCQVNNPPDFYTNGLGLINLTVLV----PPS 146
LQ + V TL + V P D G Y CQ TN +G TV + PPS
Sbjct: 646 ALQEDSRIHVDAQGTLIIQGVAPEDAGNYSCQA-------TNEVGTDQETVTLYYTDPPS 698
Query: 147 NPLCSQSGQTSVGGSTALRCSSSEGAPKPVYNWVRLGTFPTPSPGSMVQDEVSGQLILTN 206
+ +VG L C +S G P P W R G +P + SG+L +
Sbjct: 699 VSAVNAVVLVAVGEEAVLVCEAS-GVPPPRVIWYRGGLEMILAP----EGSSSGKLRIPA 753
Query: 207 LSLTSSGTYRCVATNQMGSASCELTLSV 234
+GTY C A N++G AS E+ L+V
Sbjct: 754 AQERDAGTYTCRAVNELGDASAEIQLAV 781
Score = 56.6 bits (135), Expect = 3e-08
Identities = 41/150 (27%), Positives = 71/150 (47%), Gaps = 10/150 (6%)
Query: 105 TLKLTDVHPSDTGTYLCQVNNPPDFYTNGLGLINLTVLV--PPSNPLCSQSGQTSVGGST 162
+L+++ + P+D G Y C +N NG+ ++ +LV P + + S S G
Sbjct: 570 SLEISGIIPTDGGRYQCVASN-----ANGVTRASVWLLVREAPQVSIHTSSQHFSQGVEV 624
Query: 163 ALRCSSSEGAPKPVYNWVRLGTFPTPSPGSMVQDEVSGQLILTNLSLTSSGTYRCVATNQ 222
+ CS+S G P P +W R S + + G LI+ ++ +G Y C ATN+
Sbjct: 625 KVSCSAS-GYPTPHISWSRESQ--ALQEDSRIHVDAQGTLIIQGVAPEDAGNYSCQATNE 681
Query: 223 MGSASCELTLSVTEPSQGRVAGALIGVLLG 252
+G+ +TL T+P A++ V +G
Sbjct: 682 VGTDQETVTLYYTDPPSVSAVNAVVLVAVG 711
>gi|40255013 carcinoembryonic antigen-related cell adhesion molecule
6 (non-specific cross reacting antigen) [Homo sapiens]
Length = 344
Score = 59.3 bits (142), Expect = 5e-09
Identities = 52/192 (27%), Positives = 81/192 (42%), Gaps = 24/192 (12%)
Query: 66 KPISESHPILYFTNGHLYPTGSKSKRVSLLQNPPTVGVATLKLTDVHPSDTGTYLCQVNN 125
+P ++ L++ NG P S R+ L G TL L V +D G+Y C++ N
Sbjct: 168 EPEVQNTTYLWWVNGQSLPV---SPRLQLSN-----GNMTLTLLSVKRNDAGSYECEIQN 219
Query: 126 PPDFYTNGLGLINLTVLVPPSNPLCSQS-GQTSVGGSTALRCSSSEGAPKPVYNWVRLGT 184
P N + L VL P P S S G + L C ++ P Y+W GT
Sbjct: 220 PAS--ANRSDPVTLNVLYGPDGPTISPSKANYRPGENLNLSCHAASNPPAQ-YSWFINGT 276
Query: 185 FPTPSPGSMVQDEVSGQLILTNLSLTSSGTYRCVATNQMGSASCELTLSVTEPSQGRV-- 242
F + + +L + N+++ +SG+Y C A N + +T V
Sbjct: 277 F----------QQSTQELFIPNITVNNSGSYMCQAHNSATGLNRTTVTMITVSGSAPVLS 326
Query: 243 AGALIGVLLGVL 254
A A +G+ +GVL
Sbjct: 327 AVATVGITIGVL 338
>gi|19923629 Fc receptor-like 2 precursor [Homo sapiens]
Length = 508
Score = 57.4 bits (137), Expect = 2e-08
Identities = 58/191 (30%), Positives = 82/191 (42%), Gaps = 31/191 (16%)
Query: 104 ATLKLTDVHPSDTGTYLCQVNNPPDFYTNGLGLINLTVLVPPSNP---LCSQSGQTSVGG 160
A L++ V SD G Y C+ +N ++N+ V +P S P L S Q +VG
Sbjct: 258 AELEIPAVKESDAGKYYCRADN--GHVPIQSKVVNIPVRIPVSRPVLTLRSPGAQAAVGD 315
Query: 161 STALRCSSSEGAPKPVYNW----VRLGTFPTPSPGSMVQDEVSGQLILTNLSLTS--SGT 214
L C + G+P +Y + V LG PS G NLSLT+ SG
Sbjct: 316 LLELHCEALRGSPPILYQFYHEDVTLGNSSAPSGGG----------ASFNLSLTAEHSGN 365
Query: 215 YRCVATNQMGSASCE-LTLSVTEPSQGR-------VAGALIGVL--LGVLLLSVAAFCLV 264
Y C A N +G+ E + +S++ P R V L GVL GV LL A F +
Sbjct: 366 YSCEANNGLGAQCSEAVPVSISGPDGYRRDLMTAGVLWGLFGVLGFTGVALLLYALFHKI 425
Query: 265 RFQKERGKKPK 275
+ +P+
Sbjct: 426 SGESSATNEPR 436
Score = 36.6 bits (83), Expect = 0.031
Identities = 31/120 (25%), Positives = 50/120 (41%), Gaps = 6/120 (5%)
Query: 106 LKLTDVHPSDTGTYLCQVNNPPDFYTNGLGLINLTVL-VPPSN---PLCSQSGQTSVGGS 161
L+++ V DTG+Y C+ + V +P SN + + GQ + G
Sbjct: 162 LQISAVWSEDTGSYWCKAETVTHRIRKQSLQSQIHVQRIPISNVSLEIRAPGGQVTEGQK 221
Query: 162 TALRCSSSEGAPKPVYNWVRLGTFPTPSPGSMVQDEVSGQLILTNLSLTSSGTYRCVATN 221
L CS + G ++W R T S G Q +S +L + + + +G Y C A N
Sbjct: 222 LILLCSVAGGTGNVTFSWYREAT--GTSMGKKTQRSLSAELEIPAVKESDAGKYYCRADN 279
>gi|109150416 peroxidasin [Homo sapiens]
Length = 1479
Score = 57.0 bits (136), Expect = 2e-08
Identities = 49/171 (28%), Positives = 76/171 (44%), Gaps = 16/171 (9%)
Query: 73 PILYFTNGHLYPTGSKSKRVSLLQNPPTVGVATLKLTDVHPSDTGTYLCQVNNPPDFYTN 132
P++ +T G ++S+ + + TL+++ V D G Y CQ N +
Sbjct: 462 PVIAWTKG--------GSQLSVDRRHLVLSSGTLRISGVALHDQGQYECQAVN---IIGS 510
Query: 133 GLGLINLTVLVPPSNPLCSQSGQTSV--GGSTALRCSSSEGAPKPVYNWVRLGTFPTPSP 190
+ +LTV + S T+V G + L CSS +G P+P W + G T S
Sbjct: 511 QKVVAHLTVQPRVTPVFASIPSDTTVEVGANVQLPCSS-QGEPEPAITWNKDGVQVTESG 569
Query: 191 GSMVQDEVSGQLILTNLSLTSSGTYRCVATNQMGSASCELTLSVTEPSQGR 241
+ E G L + ++ +G Y CVA N +GSAS + LSV P R
Sbjct: 570 KFHISPE--GFLTINDVGPADAGRYECVARNTIGSASVSMVLSVNVPDVSR 618
Score = 47.0 bits (110), Expect = 2e-05
Identities = 37/122 (30%), Positives = 52/122 (42%), Gaps = 3/122 (2%)
Query: 105 TLKLTDVHPSDTGTYLCQVNNPP-DFYTNGLGLINLTVLVPPSNPLCSQSGQTSVGGSTA 163
TL + + +D G Y C N + T + L P+ + Q+ + VG S
Sbjct: 301 TLMIQNTQETDQGIYQCMAKNVAGEVKTQEVTLRYFGSPARPTFVIQPQNTEVLVGESVT 360
Query: 164 LRCSSSEGAPKPVYNWVRLGTFPTPSPGSMVQDEVSGQLILTNLSLTSSGTYRCVATNQM 223
L CS++ G P P +W R P P V SG L + N+ SG Y C ATN +
Sbjct: 361 LECSAT-GHPPPRISWTRGDRTPLPVD-PRVNITPSGGLYIQNVVQGDSGEYACSATNNI 418
Query: 224 GS 225
S
Sbjct: 419 DS 420
Score = 36.2 bits (82), Expect = 0.041
Identities = 23/74 (31%), Positives = 33/74 (44%), Gaps = 1/74 (1%)
Query: 160 GSTALRCSSSEGAPKPVYNWVRLGTFPTPSPGSMVQDEVSGQLILTNLSLTSSGTYRCVA 219
G+T +EG PKP W+R + S + G L++ N T G Y+C+A
Sbjct: 260 GNTVYFTCRAEGNPKPEIIWLRNNNELSMKTDSRLNLLDDGTLMIQNTQETDQGIYQCMA 319
Query: 220 TNQMGSASC-ELTL 232
N G E+TL
Sbjct: 320 KNVAGEVKTQEVTL 333
>gi|19882241 immunoglobulin superfamily, DCC subclass, member 4
[Homo sapiens]
Length = 1250
Score = 57.0 bits (136), Expect = 2e-08
Identities = 39/136 (28%), Positives = 61/136 (44%), Gaps = 7/136 (5%)
Query: 101 VGVATLKLTDVHPSDTGTYLCQVNNPP--DFYTNGLGLINLTVLVPPSNPLCSQSGQTSV 158
+G L + + P +G Y+C+ N P DF T L VL P+ ++ +
Sbjct: 292 LGRTNLLIANAQPWHSGVYVCRANKPRTRDFAT---AAAELRVLAAPAITQAPEALSRTR 348
Query: 159 GGSTALRCSSSEGAPKPVYNWVRLGTFPTPSPGSMVQDEVSGQLILTNLSLTSSGTYRCV 218
+ C +S G P+P W+ G P+ VQ G L++T + L +G Y+CV
Sbjct: 349 ASTARFVCRAS-GEPRPALRWLHNGAPLRPNGRVKVQGG-GGSLVITQIGLQDAGYYQCV 406
Query: 219 ATNQMGSASCELTLSV 234
A N G A +L+V
Sbjct: 407 AENSAGMACAAASLAV 422
Score = 44.3 bits (103), Expect = 2e-04
Identities = 50/201 (24%), Positives = 77/201 (38%), Gaps = 21/201 (10%)
Query: 24 VEVKVPTEPLSTPLG--KTAELTCTY-STSVGDSFALEWSFVQPGKPISESHPILYFTNG 80
VE+ PL LG + A L C+ + + G + WS + G + E + NG
Sbjct: 34 VELSCGVGPLQVILGPEQAAVLNCSLGAAAAGPPTRVTWS--KDGDTLLEHDHLHLLPNG 91
Query: 81 HLYPTGSKSKRVSLLQNPPTVGVATLKLTDVHPSDTGTYLCQVNNPPDFYTNGLGLINLT 140
L+ + + S P VGV G Y C + P + ++ L
Sbjct: 92 SLWLSQPLAPNGSDESVPEAVGVIE-----------GNYSCLAHGPLGVLASQTAVVKLA 140
Query: 141 VLVPPSNPLCSQSGQTSVGGSTALRCSSSEGAPKPVYNWVRLGTFPTPSPGSMVQDEVSG 200
L S L +S G+ C EG P P+ W + P +V +G
Sbjct: 141 TLADFS--LHPESQTVEENGTARFECHI-EGLPAPIITWEKDQVTLPEEPRLIVLP--NG 195
Query: 201 QLILTNLSLTSSGTYRCVATN 221
L + ++ + +G YRCVATN
Sbjct: 196 VLQILDVQESDAGPYRCVATN 216
>gi|38490688 immunoglobulin superfamily, member 10 [Homo sapiens]
Length = 2623
Score = 56.6 bits (135), Expect = 3e-08
Identities = 55/179 (30%), Positives = 83/179 (46%), Gaps = 18/179 (10%)
Query: 64 PGKPISESHPILYFTNGHLYPTG---SKSKRVSLLQNPPTVGVATLKLTDVHPSDTGTYL 120
P + + P +++T P+G SK K+ S +Q P TL + V D G YL
Sbjct: 1669 PCEAVGNPLPTIHWTR---VPSGLDLSKRKQNSRVQVLPN---GTLSIQRVEIQDRGQYL 1722
Query: 121 CQVNNPPDFYTNGLGLINLTVLVPPSNPLCSQSGQTSV--GGSTALRCSSSEGAPKPVYN 178
C +N F T+ L + L+V+ P L ++ + +V G + L+C + EG P P
Sbjct: 1723 CSASNL--FGTDHLH-VTLSVVSYPPRILERRTKEITVHSGSTVELKCRA-EGRPSPTVT 1778
Query: 179 WVRLG--TFPTPSPGS-MVQDEVSGQLILTNLSLTSSGTYRCVATNQMGSASCELTLSV 234
W+ S GS V G L+L NLS+ G Y+CVA+N G S + + V
Sbjct: 1779 WILANQTVVSESSQGSRQAVVTVDGTLVLHNLSIYDRGFYKCVASNPGGQDSLLVKIQV 1837
Score = 45.1 bits (105), Expect = 9e-05
Identities = 36/130 (27%), Positives = 54/130 (41%), Gaps = 15/130 (11%)
Query: 105 TLKLTDVHPSDTGTYLCQVNNPPDFYTNGLGLINLTVLVPPSNPLCS----QSGQTSVGG 160
TL + + D G Y+C+ N + G LI + V++ P + +S T G
Sbjct: 2490 TLVIKEATAYDRGNYICKAQN-----SVGHTLITVPVMIVAYPPRITNRPPRSIVTRTGA 2544
Query: 161 STALRCSSSEGAPKPVYNWVR-----LGTFPTPSPGSMVQDEVSGQLILTNLSLTSSGTY 215
+ L C + G PKP W L T Q + G L++ N + SG Y
Sbjct: 2545 AFQLHCVAL-GVPKPEITWEMPDHSLLSTASKERTHGSEQLHLQGTLVIQNPQTSDSGIY 2603
Query: 216 RCVATNQMGS 225
+C A N +GS
Sbjct: 2604 KCTAKNPLGS 2613
Score = 43.5 bits (101), Expect = 3e-04
Identities = 40/139 (28%), Positives = 62/139 (44%), Gaps = 13/139 (9%)
Query: 105 TLKLTDVHPSDTGTYLCQVNNPPDFYTNGLGLINLTVLVPPSNPLCSQSGQTSVGG---S 161
TL L ++ D G Y C +NP L+ + V+ P + Q Q VG S
Sbjct: 1804 TLVLHNLSIYDRGFYKCVASNPGG---QDSLLVKIQVIAAPP-VILEQRRQVIVGTWGES 1859
Query: 162 TALRCSSSEGAPKPVYNWVRLGTFPTPSPGSMVQDEV----SGQLILTNLSLTSSGTYRC 217
L C++ +G P+P WV L P ++ +G L + NL+ + GTY C
Sbjct: 1860 LKLPCTA-KGTPQPSVYWV-LSDGTEVKPLQFTNSKLFLFSNGTLYIRNLASSDRGTYEC 1917
Query: 218 VATNQMGSASCELTLSVTE 236
+AT+ GS + L++ E
Sbjct: 1918 IATSSTGSERRVVMLTMEE 1936
Score = 42.0 bits (97), Expect = 7e-04
Identities = 38/124 (30%), Positives = 59/124 (47%), Gaps = 6/124 (4%)
Query: 105 TLKLTDVHPSDTGTYLCQVNNPPDFYTNGLGLINLTVLVPPS--NPLCSQSGQTSVGGST 162
TL++ +V SD+ ++C N + L L +L P+ NP ++ +G ST
Sbjct: 2297 TLEIRNVRLSDSADFICVARNEGGESVLVVQLEVLEMLRRPTFRNPF-NEKIVAQLGKST 2355
Query: 163 ALRCSSSEGAPKPVYNWVRL-GTFPTPSPGSMVQDEVS-GQLILTNLSLTSSGTYRCVAT 220
AL CS +G P P W+ GT + P S S G I++ + +G YRC A
Sbjct: 2356 ALNCSV-DGNPPPEIIWILPNGTRFSNGPQSYQYLIASNGSFIISKTTREDAGKYRCAAR 2414
Query: 221 NQMG 224
N++G
Sbjct: 2415 NKVG 2418
Score = 41.6 bits (96), Expect = 0.001
Identities = 37/143 (25%), Positives = 55/143 (38%), Gaps = 14/143 (9%)
Query: 85 TGSKSKRVSLLQNPPTVGVATLKLTDVHPSDTGTYLCQVNNPPDFYTNGLGLINLTVLVP 144
+G +++R +L N TL V ++ G Y C N T G + + + V
Sbjct: 2089 SGHRTRRYTLFNN------GTLYFNKVGVAEEGDYTCYAQN-----TLGKDEMKVHLTVI 2137
Query: 145 PSNPLCSQSGQTSV---GGSTALRCSSSEGAPKPVYNWVRLGTFPTPSPGSMVQDEVSGQ 201
+ P QS +T+ G TA+ G PKP W+ +G
Sbjct: 2138 TAAPRIRQSNKTNKRIKAGDTAVLDCEVTGDPKPKIFWLLPSNDMISFSIDRYTFHANGS 2197
Query: 202 LILTNLSLTSSGTYRCVATNQMG 224
L + + L SG Y CVA N G
Sbjct: 2198 LTINKVKLLDSGEYVCVARNPSG 2220
Score = 41.2 bits (95), Expect = 0.001
Identities = 36/125 (28%), Positives = 54/125 (43%), Gaps = 7/125 (5%)
Query: 105 TLKLTDVHPSDTGTYLCQVNNPPDFYTNGLGLINLTVLVPPSNPLCSQSG-QTSVGGSTA 163
TL + ++ SD GTY C + + L + P SQ + + G
Sbjct: 1901 TLYIRNLASSDRGTYECIATSSTGSERRVVMLTMEERVTSPRIEAASQKRTEVNFGDKLL 1960
Query: 164 LRCSSSEGAPKPVYNWVRLGTFPTPSP----GSMVQDEVSGQLILTNLSLTSSGTYRCVA 219
L CS++ G PKP W RL + GS + +G L + +++ SG Y CVA
Sbjct: 1961 LNCSAT-GEPKPQIMW-RLPSKAVVDQQHRVGSWIHVYPNGSLFIGSVTEKDSGVYLCVA 2018
Query: 220 TNQMG 224
N+MG
Sbjct: 2019 RNKMG 2023
Score = 34.7 bits (78), Expect = 0.12
Identities = 46/201 (22%), Positives = 70/201 (34%), Gaps = 39/201 (19%)
Query: 31 EPLSTPLGKTAELTCTYSTSVGDSFALEWSFVQPGKPISESHPILYFTNGHLYPTGSKSK 90
E + LGK+ L C+ G P E IL NG + G +S
Sbjct: 2345 EKIVAQLGKSTALNCSVD----------------GNPPPEIIWIL--PNGTRFSNGPQSY 2386
Query: 91 RVSLLQNPPTVGVATLKLTDVHPSDTGTYLCQVNNPPDFYTNGLGLINLTVLVPPSNPLC 150
+ + N + T + D G Y C N + + L +L P+
Sbjct: 2387 QYLIASNGSFIISKTTR------EDAGKYRCAARNKVGY------IEKLVILEIGQKPVI 2434
Query: 151 SQSGQTSVGG----STALRCSSSEGAPKPVYNWVRLGTFPTPSP---GSMVQDEVSGQLI 203
+V G S +L C S +G PKP W + P G + + +G L+
Sbjct: 2435 LTYAPGTVKGISGESLSLHCVS-DGIPKPNIKWTMPSGYVVDRPQINGKYILHD-NGTLV 2492
Query: 204 LTNLSLTSSGTYRCVATNQMG 224
+ + G Y C A N +G
Sbjct: 2493 IKEATAYDRGNYICKAQNSVG 2513
Score = 33.1 bits (74), Expect = 0.35
Identities = 23/85 (27%), Positives = 39/85 (45%), Gaps = 7/85 (8%)
Query: 158 VGGSTALRCSSSEGAPKPVYNWVRLGTFPTPSP-----GSMVQDEVSGQLILTNLSLTSS 212
VGG+ L C +G P P +W+ +P G ++ D+ SG+L L +
Sbjct: 489 VGGTVGLNCPG-QGDPTPHVDWLLADGSKVRAPYVSEDGRILIDK-SGKLELQMADSFDT 546
Query: 213 GTYRCVATNQMGSASCELTLSVTEP 237
G Y C+++N + ++V EP
Sbjct: 547 GVYHCISSNYDDADILTYRITVVEP 571
Score = 31.6 bits (70), Expect = 1.0
Identities = 37/172 (21%), Positives = 65/172 (37%), Gaps = 47/172 (27%)
Query: 81 HLYPTGSKSKRVSLLQNPPTVGVATLKLTDVHPSDTGTYLCQVNNPPDFYTNGLGLINLT 140
H+YP GS L + V D+G YLC N + L L++++
Sbjct: 1994 HVYPNGS------------------LFIGSVTEKDSGVYLCVARNKMG---DDLILMHVS 2032
Query: 141 VLVPPSNPLCSQSGQTSV--GGSTALRCSSSEGAPKPVYNWVRLGTFPTPSPGSMVQDEV 198
+ + P+ Q + V G + C +S G+P P +W + G+M+ + +
Sbjct: 2033 LRLKPAKIDHKQYFRKQVLHGKDFQVDCKAS-GSPVPEISW-------SLPDGTMINNAM 2084
Query: 199 ----------------SGQLILTNLSLTSSGTYRCVATNQMGSASCELTLSV 234
+G L + + G Y C A N +G ++ L+V
Sbjct: 2085 QADDSGHRTRRYTLFNNGTLYFNKVGVAEEGDYTCYAQNTLGKDEMKVHLTV 2136
Score = 29.6 bits (65), Expect = 3.8
Identities = 32/122 (26%), Positives = 47/122 (38%), Gaps = 8/122 (6%)
Query: 106 LKLTDVHPSDTGTYLCQVNNPPDFYTNGLGLINLTVLVPPSNPLCSQSG---QTSVGGST 162
L+L DTG Y C +N Y + L +V P ++G +G +
Sbjct: 536 LELQMADSFDTGVYHCISSN----YDDADILTYRITVVEPLVEAYQENGIHHTVFIGETL 591
Query: 163 ALRCSSSEGAPKPVYNWVRLGTFPTPSPGSMVQDEVSGQLILTNLSLTSSGTYRCVATNQ 222
L C S+ G P +WV G + +G L + ++ G YRCVA N
Sbjct: 592 DLPCHST-GIPDASISWVIPGNNVLYQSSRDKKVLNNGTLRILQVTPKDQGYYRCVAANP 650
Query: 223 MG 224
G
Sbjct: 651 SG 652
Score = 29.6 bits (65), Expect = 3.8
Identities = 29/90 (32%), Positives = 42/90 (46%), Gaps = 26/90 (28%)
Query: 37 LGKTAELTCTYSTSVGDSFALEWSFVQPGKPISESHPILYFTNGHLYPTGSKSKRVSLLQ 96
+G+T +L C +ST + D+ ++ W V PG N LY + S+ K+V L
Sbjct: 587 IGETLDLPC-HSTGIPDA-SISW--VIPG-------------NNVLYQS-SRDKKV--LN 626
Query: 97 NPPTVGVATLKLTDVHPSDTGTYLCQVNNP 126
N TL++ V P D G Y C NP
Sbjct: 627 N------GTLRILQVTPKDQGYYRCVAANP 650
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.132 0.392
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,282,851
Number of Sequences: 37866
Number of extensions: 701053
Number of successful extensions: 3550
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 187
Number of HSP's successfully gapped in prelim test: 292
Number of HSP's that attempted gapping in prelim test: 1845
Number of HSP's gapped (non-prelim): 1487
length of query: 327
length of database: 18,247,518
effective HSP length: 103
effective length of query: 224
effective length of database: 14,347,320
effective search space: 3213799680
effective search space used: 3213799680
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.