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Search of human proteins with 21361290
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|21361290 protein phosphatase 3, catalytic subunit, gamma
[Homo sapiens]
(512 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|21361290 protein phosphatase 3, catalytic subunit, gamma [Hom... 1046 0.0
gi|6715568 protein phosphatase 3, catalytic subunit, alpha isofo... 860 0.0
gi|11036640 protein phosphatase 3, catalytic subunit, beta isofo... 852 0.0
gi|215272352 protein phosphatase 3, catalytic subunit, beta isof... 850 0.0
gi|194688147 protein phosphatase 3, catalytic subunit, alpha iso... 837 0.0
gi|215272354 protein phosphatase 3, catalytic subunit, beta isof... 829 0.0
gi|194688149 protein phosphatase 3, catalytic subunit, alpha iso... 724 0.0
gi|56790945 protein phosphatase 1, catalytic subunit, alpha isof... 222 7e-58
gi|4506003 protein phosphatase 1, catalytic subunit, alpha isofo... 222 7e-58
gi|4506007 protein phosphatase 1, catalytic subunit, gamma isofo... 221 2e-57
gi|46249376 protein phosphatase 1, catalytic subunit, beta isofo... 216 3e-56
gi|4506005 protein phosphatase 1, catalytic subunit, beta isofor... 216 3e-56
gi|57222565 protein phosphatase 2, catalytic subunit, beta isofo... 215 7e-56
gi|4758952 protein phosphatase 2, catalytic subunit, beta isofor... 215 7e-56
gi|4506027 protein phosphatase 4, catalytic subunit [Homo sapiens] 215 9e-56
gi|4506017 protein phosphatase 2, catalytic subunit, alpha isofo... 212 6e-55
gi|5453958 protein phosphatase 5, catalytic subunit [Homo sapiens] 209 6e-54
gi|45827798 protein phosphatase 1, catalytic subunit, alpha isof... 207 2e-53
gi|183603929 protein phosphatase 6, catalytic subunit isoform a ... 206 4e-53
gi|4506029 protein phosphatase 6, catalytic subunit isoform b [H... 206 4e-53
gi|183603931 protein phosphatase 6, catalytic subunit isoform c ... 170 3e-42
gi|23312374 protein phosphatase with EF hand calcium-binding dom... 119 9e-27
gi|23312380 protein phosphatase with EF hand calcium-binding dom... 108 2e-23
gi|239752750 PREDICTED: similar to protein phosphatase 2, cataly... 98 2e-20
gi|239747318 PREDICTED: similar to protein phosphatase 2, cataly... 98 2e-20
gi|239741140 PREDICTED: similar to protein phosphatase 2, cataly... 98 2e-20
gi|23312386 serine/threonine protein phosphatase with EF-hand mo... 98 2e-20
gi|23312378 protein phosphatase with EF hand calcium-binding dom... 91 2e-18
gi|4506875 selectin L precursor [Homo sapiens] 31 3.1
gi|187608577 CASP8 and FADD-like apoptosis regulator isoform 1 [... 31 3.1
>gi|21361290 protein phosphatase 3, catalytic subunit, gamma [Homo
sapiens]
Length = 512
Score = 1046 bits (2705), Expect = 0.0
Identities = 512/512 (100%), Positives = 512/512 (100%)
Query: 1 MSGRRFHLSTTDRVIKAVPFPPTQRLTFKEVFENGKPKVDVLKNHLVKEGRLEEEVALKI 60
MSGRRFHLSTTDRVIKAVPFPPTQRLTFKEVFENGKPKVDVLKNHLVKEGRLEEEVALKI
Sbjct: 1 MSGRRFHLSTTDRVIKAVPFPPTQRLTFKEVFENGKPKVDVLKNHLVKEGRLEEEVALKI 60
Query: 61 INDGAAILRQEKTMIEVDAPITVCGDIHGQFFDLMKLFEVGGSPSNTRYLFLGDYVDRGY 120
INDGAAILRQEKTMIEVDAPITVCGDIHGQFFDLMKLFEVGGSPSNTRYLFLGDYVDRGY
Sbjct: 61 INDGAAILRQEKTMIEVDAPITVCGDIHGQFFDLMKLFEVGGSPSNTRYLFLGDYVDRGY 120
Query: 121 FSIECVLYLWSLKINHPKTLFLLRGNHECRHLTDYFTFKQECRIKYSEQVYDACMETFDC 180
FSIECVLYLWSLKINHPKTLFLLRGNHECRHLTDYFTFKQECRIKYSEQVYDACMETFDC
Sbjct: 121 FSIECVLYLWSLKINHPKTLFLLRGNHECRHLTDYFTFKQECRIKYSEQVYDACMETFDC 180
Query: 181 LPLAALLNQQFLCVHGGMSPEITSLDDIRKLDRFTEPPAFGPVCDLLWSDPSEDYGNEKT 240
LPLAALLNQQFLCVHGGMSPEITSLDDIRKLDRFTEPPAFGPVCDLLWSDPSEDYGNEKT
Sbjct: 181 LPLAALLNQQFLCVHGGMSPEITSLDDIRKLDRFTEPPAFGPVCDLLWSDPSEDYGNEKT 240
Query: 241 LEHYTHNTVRGCSYFYSYPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQATGFPSLIT 300
LEHYTHNTVRGCSYFYSYPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQATGFPSLIT
Sbjct: 241 LEHYTHNTVRGCSYFYSYPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQATGFPSLIT 300
Query: 301 IFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEM 360
IFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEM
Sbjct: 301 IFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEM 360
Query: 361 LVNVLNICSDDELISDDEAEGSTTVRKEIIRNKIRAIGKMARVFSILRQESESVLTLKGL 420
LVNVLNICSDDELISDDEAEGSTTVRKEIIRNKIRAIGKMARVFSILRQESESVLTLKGL
Sbjct: 361 LVNVLNICSDDELISDDEAEGSTTVRKEIIRNKIRAIGKMARVFSILRQESESVLTLKGL 420
Query: 421 TPTGTLPLGVLSGGKQTIETATVEAVEAREAIRGFSLQHKIRSFEEARGLDRINERMPPR 480
TPTGTLPLGVLSGGKQTIETATVEAVEAREAIRGFSLQHKIRSFEEARGLDRINERMPPR
Sbjct: 421 TPTGTLPLGVLSGGKQTIETATVEAVEAREAIRGFSLQHKIRSFEEARGLDRINERMPPR 480
Query: 481 KDSIHAGGPMKSVTSAHSHAAHRSDQGKKAHS 512
KDSIHAGGPMKSVTSAHSHAAHRSDQGKKAHS
Sbjct: 481 KDSIHAGGPMKSVTSAHSHAAHRSDQGKKAHS 512
>gi|6715568 protein phosphatase 3, catalytic subunit, alpha isoform
isoform 1 [Homo sapiens]
Length = 521
Score = 860 bits (2221), Expect = 0.0
Identities = 410/501 (81%), Positives = 464/501 (92%), Gaps = 3/501 (0%)
Query: 8 LSTTDRVIKAVPFPPTQRLTFKEVFEN-GKPKVDVLKNHLVKEGRLEEEVALKIINDGAA 66
LSTTDRV+KAVPFPP+ RLT KEVF+N GKP+VD+LK HL+KEGRLEE VAL+II +GA+
Sbjct: 11 LSTTDRVVKAVPFPPSHRLTAKEVFDNDGKPRVDILKAHLMKEGRLEESVALRIITEGAS 70
Query: 67 ILRQEKTMIEVDAPITVCGDIHGQFFDLMKLFEVGGSPSNTRYLFLGDYVDRGYFSIECV 126
ILRQEK ++++DAP+TVCGDIHGQFFDLMKLFEVGGSP+NTRYLFLGDYVDRGYFSIECV
Sbjct: 71 ILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFSIECV 130
Query: 127 LYLWSLKINHPKTLFLLRGNHECRHLTDYFTFKQECRIKYSEQVYDACMETFDCLPLAAL 186
LYLW+LKI +PKTLFLLRGNHECRHLT+YFTFKQEC+IKYSE+VYDACM+ FDCLPLAAL
Sbjct: 131 LYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYDACMDAFDCLPLAAL 190
Query: 187 LNQQFLCVHGGMSPEITSLDDIRKLDRFTEPPAFGPVCDLLWSDPSEDYGNEKTLEHYTH 246
+NQQFLCVHGG+SPEI +LDDIRKLDRF EPPA+GP+CD+LWSDP ED+GNEKT EH+TH
Sbjct: 191 MNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSDPLEDFGNEKTQEHFTH 250
Query: 247 NTVRGCSYFYSYPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQATGFPSLITIFSAPN 306
NTVRGCSYFYSYPAVCEFLQ+NNLLSI+RAHEAQDAGYRMYRKSQ TGFPSLITIFSAPN
Sbjct: 251 NTVRGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPN 310
Query: 307 YLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEMLVNVLN 366
YLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEMLVNVLN
Sbjct: 311 YLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEMLVNVLN 370
Query: 367 ICSDDELISDDEA-EGST-TVRKEIIRNKIRAIGKMARVFSILRQESESVLTLKGLTPTG 424
ICSDDEL S+++ +G+T RKE+IRNKIRAIGKMARVFS+LR+ESESVLTLKGLTPTG
Sbjct: 371 ICSDDELGSEEDGFDGATAAARKEVIRNKIRAIGKMARVFSVLREESESVLTLKGLTPTG 430
Query: 425 TLPLGVLSGGKQTIETATVEAVEAREAIRGFSLQHKIRSFEEARGLDRINERMPPRKDSI 484
LP GVLSGGKQT+++ATVEA+EA EAI+GFS QHKI SFEEA+GLDRINERMPPR+D++
Sbjct: 431 MLPSGVLSGGKQTLQSATVEAIEADEAIKGFSPQHKITSFEEAKGLDRINERMPPRRDAM 490
Query: 485 HAGGPMKSVTSAHSHAAHRSD 505
+ + S+ A + + +D
Sbjct: 491 PSDANLNSINKALTSETNGTD 511
>gi|11036640 protein phosphatase 3, catalytic subunit, beta isoform
b [Homo sapiens]
Length = 524
Score = 852 bits (2202), Expect = 0.0
Identities = 410/494 (82%), Positives = 459/494 (92%), Gaps = 4/494 (0%)
Query: 12 DRVIKAVPFPPTQRLTFKEVFE-NGKPKVDVLKNHLVKEGRLEEEVALKIINDGAAILRQ 70
DRV+KAVPFPPT RLT +EVF+ +G P+VDVLKNHLVKEGR++EE+AL+IIN+GAAILR+
Sbjct: 24 DRVVKAVPFPPTHRLTSEEVFDLDGIPRVDVLKNHLVKEGRVDEEIALRIINEGAAILRR 83
Query: 71 EKTMIEVDAPITVCGDIHGQFFDLMKLFEVGGSPSNTRYLFLGDYVDRGYFSIECVLYLW 130
EKTMIEV+APITVCGDIHGQFFDLMKLFEVGGSP+NTRYLFLGDYVDRGYFSIECVLYLW
Sbjct: 84 EKTMIEVEAPITVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFSIECVLYLW 143
Query: 131 SLKINHPKTLFLLRGNHECRHLTDYFTFKQECRIKYSEQVYDACMETFDCLPLAALLNQQ 190
LKI +P TLFLLRGNHECRHLT+YFTFKQEC+IKYSE+VY+ACME FD LPLAALLNQQ
Sbjct: 144 VLKILYPSTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYEACMEAFDSLPLAALLNQQ 203
Query: 191 FLCVHGGMSPEITSLDDIRKLDRFTEPPAFGPVCDLLWSDPSEDYGNEKTLEHYTHNTVR 250
FLCVHGG+SPEI +LDDIR+LDRF EPPAFGP+CDLLWSDPSED+GNEK+ EH++HNTVR
Sbjct: 204 FLCVHGGLSPEIHTLDDIRRLDRFKEPPAFGPMCDLLWSDPSEDFGNEKSQEHFSHNTVR 263
Query: 251 GCSYFYSYPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQATGFPSLITIFSAPNYLDV 310
GCSYFY+YPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQ TGFPSLITIFSAPNYLDV
Sbjct: 264 GCSYFYNYPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDV 323
Query: 311 YNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEMLVNVLNICSD 370
YNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEMLVNVL+ICSD
Sbjct: 324 YNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEMLVNVLSICSD 383
Query: 371 DELIS--DDEAEGSTTVRKEIIRNKIRAIGKMARVFSILRQESESVLTLKGLTPTGTLPL 428
DEL++ +D+ +GS RKEIIRNKIRAIGKMARVFS+LR+ESESVLTLKGLTPTG LP
Sbjct: 384 DELMTEGEDQFDGSAAARKEIIRNKIRAIGKMARVFSVLREESESVLTLKGLTPTGMLPS 443
Query: 429 GVLSGGKQTIETATVEAVEAREAIRGFSLQHKIRSFEEARGLDRINERMPPRKDSIHAGG 488
GVL+GG+QT+++ATVEA+EA +AIRGFS H+I SFEEA+GLDRINERMPPRKD++ G
Sbjct: 444 GVLAGGRQTLQSATVEAIEAEKAIRGFSPPHRICSFEEAKGLDRINERMPPRKDAVQQDG 503
Query: 489 PMKSVTSAHSHAAH 502
S+ +AH+ H
Sbjct: 504 -FNSLNTAHATENH 516
>gi|215272352 protein phosphatase 3, catalytic subunit, beta isoform
a [Homo sapiens]
Length = 525
Score = 850 bits (2197), Expect = 0.0
Identities = 410/495 (82%), Positives = 458/495 (92%), Gaps = 5/495 (1%)
Query: 12 DRVIKAVPFPPTQRLTFKEVFE-NGKPKVDVLKNHLVKEGRLEEEVALKIINDGAAILRQ 70
DRV+KAVPFPPT RLT +EVF+ +G P+VDVLKNHLVKEGR++EE+AL+IIN+GAAILR+
Sbjct: 24 DRVVKAVPFPPTHRLTSEEVFDLDGIPRVDVLKNHLVKEGRVDEEIALRIINEGAAILRR 83
Query: 71 EKTMIEVDAPITVCGDIHGQFFDLMKLFEVGGSPSNTRYLFLGDYVDRGYFSIECVLYLW 130
EKTMIEV+APITVCGDIHGQFFDLMKLFEVGGSP+NTRYLFLGDYVDRGYFSIECVLYLW
Sbjct: 84 EKTMIEVEAPITVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFSIECVLYLW 143
Query: 131 SLKINHPKTLFLLRGNHECRHLTDYFTFKQECRIKYSEQVYDACMETFDCLPLAALLNQQ 190
LKI +P TLFLLRGNHECRHLT+YFTFKQEC+IKYSE+VY+ACME FD LPLAALLNQQ
Sbjct: 144 VLKILYPSTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYEACMEAFDSLPLAALLNQQ 203
Query: 191 FLCVHGGMSPEITSLDDIRKLDRFTEPPAFGPVCDLLWSDPSEDYGNEKTLEHYTHNTVR 250
FLCVHGG+SPEI +LDDIR+LDRF EPPAFGP+CDLLWSDPSED+GNEK+ EH++HNTVR
Sbjct: 204 FLCVHGGLSPEIHTLDDIRRLDRFKEPPAFGPMCDLLWSDPSEDFGNEKSQEHFSHNTVR 263
Query: 251 GCSYFYSYPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQATGFPSLITIFSAPNYLDV 310
GCSYFY+YPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQ TGFPSLITIFSAPNYLDV
Sbjct: 264 GCSYFYNYPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDV 323
Query: 311 YNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEMLVNVLNICSD 370
YNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEMLVNVL+ICSD
Sbjct: 324 YNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEMLVNVLSICSD 383
Query: 371 DELISDDEAE---GSTTVRKEIIRNKIRAIGKMARVFSILRQESESVLTLKGLTPTGTLP 427
DEL+++ E + GS RKEIIRNKIRAIGKMARVFS+LR+ESESVLTLKGLTPTG LP
Sbjct: 384 DELMTEGEDQFDVGSAAARKEIIRNKIRAIGKMARVFSVLREESESVLTLKGLTPTGMLP 443
Query: 428 LGVLSGGKQTIETATVEAVEAREAIRGFSLQHKIRSFEEARGLDRINERMPPRKDSIHAG 487
GVL+GG+QT+++ATVEA+EA +AIRGFS H+I SFEEA+GLDRINERMPPRKD++
Sbjct: 444 SGVLAGGRQTLQSATVEAIEAEKAIRGFSPPHRICSFEEAKGLDRINERMPPRKDAVQQD 503
Query: 488 GPMKSVTSAHSHAAH 502
G S+ +AH+ H
Sbjct: 504 G-FNSLNTAHATENH 517
>gi|194688147 protein phosphatase 3, catalytic subunit, alpha
isoform isoform 2 [Homo sapiens]
Length = 511
Score = 837 bits (2163), Expect = 0.0
Identities = 402/501 (80%), Positives = 455/501 (90%), Gaps = 13/501 (2%)
Query: 8 LSTTDRVIKAVPFPPTQRLTFKEVFEN-GKPKVDVLKNHLVKEGRLEEEVALKIINDGAA 66
LSTTDRV+KAVPFPP+ RLT KEVF+N GKP+VD+LK HL+KEGRLEE VAL+II +GA+
Sbjct: 11 LSTTDRVVKAVPFPPSHRLTAKEVFDNDGKPRVDILKAHLMKEGRLEESVALRIITEGAS 70
Query: 67 ILRQEKTMIEVDAPITVCGDIHGQFFDLMKLFEVGGSPSNTRYLFLGDYVDRGYFSIECV 126
ILRQEK ++++DAP+TVCGDIHGQFFDLMKLFEVGGSP+NTRYLFLGDYVDRGYFSIECV
Sbjct: 71 ILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFSIECV 130
Query: 127 LYLWSLKINHPKTLFLLRGNHECRHLTDYFTFKQECRIKYSEQVYDACMETFDCLPLAAL 186
LYLW+LKI +PKTLFLLRGNHECRHLT+YFTFKQEC+IKYSE+VYDACM+ FDCLPLAAL
Sbjct: 131 LYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYDACMDAFDCLPLAAL 190
Query: 187 LNQQFLCVHGGMSPEITSLDDIRKLDRFTEPPAFGPVCDLLWSDPSEDYGNEKTLEHYTH 246
+NQQFLCVHGG+SPEI +LDDIRKLDRF EPPA+GP+CD+LWSDP ED+GNEKT EH+TH
Sbjct: 191 MNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSDPLEDFGNEKTQEHFTH 250
Query: 247 NTVRGCSYFYSYPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQATGFPSLITIFSAPN 306
NTVRGCSYFYSYPAVCEFLQ+NNLLSI+RAHEAQDAGYRMYRKSQ TGFPSLITIFSAPN
Sbjct: 251 NTVRGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPN 310
Query: 307 YLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEMLVNVLN 366
YLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEMLVNVLN
Sbjct: 311 YLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEMLVNVLN 370
Query: 367 ICSDDELISDDEA-EGST-TVRKEIIRNKIRAIGKMARVFSILRQESESVLTLKGLTPTG 424
ICSDDEL S+++ +G+T RKE+IRNKIRAIGKMARVFS+LR+ESESVLTLKGLTPTG
Sbjct: 371 ICSDDELGSEEDGFDGATAAARKEVIRNKIRAIGKMARVFSVLREESESVLTLKGLTPTG 430
Query: 425 TLPLGVLSGGKQTIETATVEAVEAREAIRGFSLQHKIRSFEEARGLDRINERMPPRKDSI 484
LP GVLSGGKQT+++ AI+GFS QHKI SFEEA+GLDRINERMPPR+D++
Sbjct: 431 MLPSGVLSGGKQTLQS----------AIKGFSPQHKITSFEEAKGLDRINERMPPRRDAM 480
Query: 485 HAGGPMKSVTSAHSHAAHRSD 505
+ + S+ A + + +D
Sbjct: 481 PSDANLNSINKALTSETNGTD 501
>gi|215272354 protein phosphatase 3, catalytic subunit, beta isoform
c [Homo sapiens]
Length = 515
Score = 829 bits (2141), Expect = 0.0
Identities = 403/495 (81%), Positives = 449/495 (90%), Gaps = 15/495 (3%)
Query: 12 DRVIKAVPFPPTQRLTFKEVFE-NGKPKVDVLKNHLVKEGRLEEEVALKIINDGAAILRQ 70
DRV+KAVPFPPT RLT +EVF+ +G P+VDVLKNHLVKEGR++EE+AL+IIN+GAAILR+
Sbjct: 24 DRVVKAVPFPPTHRLTSEEVFDLDGIPRVDVLKNHLVKEGRVDEEIALRIINEGAAILRR 83
Query: 71 EKTMIEVDAPITVCGDIHGQFFDLMKLFEVGGSPSNTRYLFLGDYVDRGYFSIECVLYLW 130
EKTMIEV+APITVCGDIHGQFFDLMKLFEVGGSP+NTRYLFLGDYVDRGYFSIECVLYLW
Sbjct: 84 EKTMIEVEAPITVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFSIECVLYLW 143
Query: 131 SLKINHPKTLFLLRGNHECRHLTDYFTFKQECRIKYSEQVYDACMETFDCLPLAALLNQQ 190
LKI +P TLFLLRGNHECRHLT+YFTFKQEC+IKYSE+VY+ACME FD LPLAALLNQQ
Sbjct: 144 VLKILYPSTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYEACMEAFDSLPLAALLNQQ 203
Query: 191 FLCVHGGMSPEITSLDDIRKLDRFTEPPAFGPVCDLLWSDPSEDYGNEKTLEHYTHNTVR 250
FLCVHGG+SPEI +LDDIR+LDRF EPPAFGP+CDLLWSDPSED+GNEK+ EH++HNTVR
Sbjct: 204 FLCVHGGLSPEIHTLDDIRRLDRFKEPPAFGPMCDLLWSDPSEDFGNEKSQEHFSHNTVR 263
Query: 251 GCSYFYSYPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQATGFPSLITIFSAPNYLDV 310
GCSYFY+YPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQ TGFPSLITIFSAPNYLDV
Sbjct: 264 GCSYFYNYPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDV 323
Query: 311 YNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEMLVNVLNICSD 370
YNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEMLVNVL+ICSD
Sbjct: 324 YNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEMLVNVLSICSD 383
Query: 371 DELISDDEAE---GSTTVRKEIIRNKIRAIGKMARVFSILRQESESVLTLKGLTPTGTLP 427
DEL+++ E + GS RKEIIRNKIRAIGKMARVFS+LR+ESESVLTLKGLTPTG LP
Sbjct: 384 DELMTEGEDQFDVGSAAARKEIIRNKIRAIGKMARVFSVLREESESVLTLKGLTPTGMLP 443
Query: 428 LGVLSGGKQTIETATVEAVEAREAIRGFSLQHKIRSFEEARGLDRINERMPPRKDSIHAG 487
GVL+GG+QT+++ AIRGFS H+I SFEEA+GLDRINERMPPRKD++
Sbjct: 444 SGVLAGGRQTLQS----------AIRGFSPPHRICSFEEAKGLDRINERMPPRKDAVQQD 493
Query: 488 GPMKSVTSAHSHAAH 502
G S+ +AH+ H
Sbjct: 494 G-FNSLNTAHATENH 507
>gi|194688149 protein phosphatase 3, catalytic subunit, alpha
isoform isoform 3 [Homo sapiens]
Length = 469
Score = 724 bits (1870), Expect = 0.0
Identities = 360/501 (71%), Positives = 413/501 (82%), Gaps = 55/501 (10%)
Query: 8 LSTTDRVIKAVPFPPTQRLTFKEVFEN-GKPKVDVLKNHLVKEGRLEEEVALKIINDGAA 66
LSTTDRV+KAVPFPP+ RLT KEVF+N GKP+VD+LK HL+KEGRLEE VAL+II +GA+
Sbjct: 11 LSTTDRVVKAVPFPPSHRLTAKEVFDNDGKPRVDILKAHLMKEGRLEESVALRIITEGAS 70
Query: 67 ILRQEKTMIEVDAPITVCGDIHGQFFDLMKLFEVGGSPSNTRYLFLGDYVDRGYFSIECV 126
ILRQEK ++++DAP+TVCGDIHGQFFDLMKLFEVGGSP+NTRYLFLGDYVDRGYFSIECV
Sbjct: 71 ILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFSIECV 130
Query: 127 LYLWSLKINHPKTLFLLRGNHECRHLTDYFTFKQECRIKYSEQVYDACMETFDCLPLAAL 186
LYLW+LKI +PKTLFLLRGNHECRHLT+YFTFKQEC+IKYSE+VYDACM+ FDCLPLAAL
Sbjct: 131 LYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYDACMDAFDCLPLAAL 190
Query: 187 LNQQFLCVHGGMSPEITSLDDIRKLDRFTEPPAFGPVCDLLWSDPSEDYGNEKTLEHYTH 246
+NQQFLCVHGG+SPEI +LDDIRKLDRF EPPA+GP+CD+LWSDP ED+GNEKT EH+TH
Sbjct: 191 MNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSDPLEDFGNEKTQEHFTH 250
Query: 247 NTVRGCSYFYSYPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQATGFPSLITIFSAPN 306
NTVRGCSYFYSYPAVCEFLQ+NNLLSI+RAHEAQDAGYRMYRKSQ TGFPSLITIFSAPN
Sbjct: 251 NTVRGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPN 310
Query: 307 YLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEMLVNVLN 366
YLDVYNN KVTEMLVNVLN
Sbjct: 311 YLDVYNN------------------------------------------KVTEMLVNVLN 328
Query: 367 ICSDDELISDDEA-EGST-TVRKEIIRNKIRAIGKMARVFSILRQESESVLTLKGLTPTG 424
ICSDDEL S+++ +G+T RKE+IRNKIRAIGKMARVFS+LR+ESESVLTLKGLTPTG
Sbjct: 329 ICSDDELGSEEDGFDGATAAARKEVIRNKIRAIGKMARVFSVLREESESVLTLKGLTPTG 388
Query: 425 TLPLGVLSGGKQTIETATVEAVEAREAIRGFSLQHKIRSFEEARGLDRINERMPPRKDSI 484
LP GVLSGGKQT+++ AI+GFS QHKI SFEEA+GLDRINERMPPR+D++
Sbjct: 389 MLPSGVLSGGKQTLQS----------AIKGFSPQHKITSFEEAKGLDRINERMPPRRDAM 438
Query: 485 HAGGPMKSVTSAHSHAAHRSD 505
+ + S+ A + + +D
Sbjct: 439 PSDANLNSINKALTSETNGTD 459
>gi|56790945 protein phosphatase 1, catalytic subunit, alpha isoform
3 [Homo sapiens]
Length = 341
Score = 222 bits (565), Expect = 7e-58
Identities = 104/259 (40%), Positives = 166/259 (64%), Gaps = 13/259 (5%)
Query: 67 ILRQEKTMIEVDAPITVCGDIHGQFFDLMKLFEVGGSPSNTRYLFLGDYVDRGYFSIECV 126
I + ++E++AP+ +CGDIHGQ++DL++LFE GG P + YLFLGDYVDRG S+E +
Sbjct: 56 IFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETI 115
Query: 127 LYLWSLKINHPKTLFLLRGNHECRHLTDYFTFKQECRIKYSEQVYDACMETFDCLPLAAL 186
L + KI +P+ FLLRGNHEC + + F EC+ +Y+ +++ + F+CLP+AA+
Sbjct: 116 CLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAI 175
Query: 187 LNQQFLCVHGGMSPEITSLDDIRKLDRFTEPPAFGPVCDLLWSDPSEDYGNEKTLEHYTH 246
++++ C HGG+SP++ S++ IR++ R T+ P G +CDLLWSDP +D ++ +
Sbjct: 176 VDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKD------VQGWGE 229
Query: 247 NTVRGCSYFYSYPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQATGFPSLITIFSAPN 306
N RG S+ + V +FL ++L I RAH+ + GY + K Q L+T+FSAPN
Sbjct: 230 ND-RGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQ------LVTLFSAPN 282
Query: 307 YLDVYNNKAAVLKYENNVM 325
Y ++N A++ + +M
Sbjct: 283 YCGEFDNAGAMMSVDETLM 301
>gi|4506003 protein phosphatase 1, catalytic subunit, alpha isoform
1 [Homo sapiens]
Length = 330
Score = 222 bits (565), Expect = 7e-58
Identities = 104/259 (40%), Positives = 166/259 (64%), Gaps = 13/259 (5%)
Query: 67 ILRQEKTMIEVDAPITVCGDIHGQFFDLMKLFEVGGSPSNTRYLFLGDYVDRGYFSIECV 126
I + ++E++AP+ +CGDIHGQ++DL++LFE GG P + YLFLGDYVDRG S+E +
Sbjct: 45 IFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETI 104
Query: 127 LYLWSLKINHPKTLFLLRGNHECRHLTDYFTFKQECRIKYSEQVYDACMETFDCLPLAAL 186
L + KI +P+ FLLRGNHEC + + F EC+ +Y+ +++ + F+CLP+AA+
Sbjct: 105 CLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAI 164
Query: 187 LNQQFLCVHGGMSPEITSLDDIRKLDRFTEPPAFGPVCDLLWSDPSEDYGNEKTLEHYTH 246
++++ C HGG+SP++ S++ IR++ R T+ P G +CDLLWSDP +D ++ +
Sbjct: 165 VDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKD------VQGWGE 218
Query: 247 NTVRGCSYFYSYPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQATGFPSLITIFSAPN 306
N RG S+ + V +FL ++L I RAH+ + GY + K Q L+T+FSAPN
Sbjct: 219 ND-RGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQ------LVTLFSAPN 271
Query: 307 YLDVYNNKAAVLKYENNVM 325
Y ++N A++ + +M
Sbjct: 272 YCGEFDNAGAMMSVDETLM 290
>gi|4506007 protein phosphatase 1, catalytic subunit, gamma isoform
[Homo sapiens]
Length = 323
Score = 221 bits (562), Expect = 2e-57
Identities = 107/281 (38%), Positives = 170/281 (60%), Gaps = 19/281 (6%)
Query: 48 KEGRLEEEVALKIINDGAAILRQEKTMIEVDAPITVCGDIHGQFFDLMKLFEVGGSPSNT 107
K +L+E + I + ++E++AP+ +CGDIHGQ++DL++LFE GG P +
Sbjct: 26 KNVQLQENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPES 85
Query: 108 RYLFLGDYVDRGYFSIECVLYLWSLKINHPKTLFLLRGNHECRHLTDYFTFKQECRIKYS 167
YLFLGDYVDRG S+E + L + KI +P+ FLLRGNHEC + + F EC+ +Y+
Sbjct: 86 NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYN 145
Query: 168 EQVYDACMETFDCLPLAALLNQQFLCVHGGMSPEITSLDDIRKLDRFTEPPAFGPVCDLL 227
+++ + F+CLP+AA+++++ C HGG+SP++ S++ IR++ R T+ P G +CDLL
Sbjct: 146 IKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLL 205
Query: 228 WSDPSED---YGNEKTLEHYTHNTVRGCSYFYSYPAVCEFLQNNNLLSIIRAHEAQDAGY 284
WSDP +D +G RG S+ + V +FL ++L I RAH+ + GY
Sbjct: 206 WSDPDKDVLGWGEND----------RGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGY 255
Query: 285 RMYRKSQATGFPSLITIFSAPNYLDVYNNKAAVLKYENNVM 325
+ K Q L+T+FSAPNY ++N A++ + +M
Sbjct: 256 EFFAKRQ------LVTLFSAPNYCGEFDNAGAMMSVDETLM 290
>gi|46249376 protein phosphatase 1, catalytic subunit, beta isoform
1 [Homo sapiens]
Length = 327
Score = 216 bits (551), Expect = 3e-56
Identities = 102/259 (39%), Positives = 163/259 (62%), Gaps = 13/259 (5%)
Query: 67 ILRQEKTMIEVDAPITVCGDIHGQFFDLMKLFEVGGSPSNTRYLFLGDYVDRGYFSIECV 126
I + ++E++AP+ +CGDIHGQ+ DL++LFE GG P YLFLGDYVDRG S+E +
Sbjct: 44 IFLSQPILLELEAPLKICGDIHGQYTDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETI 103
Query: 127 LYLWSLKINHPKTLFLLRGNHECRHLTDYFTFKQECRIKYSEQVYDACMETFDCLPLAAL 186
L + KI +P+ FLLRGNHEC + + F EC+ +++ +++ + F+CLP+AA+
Sbjct: 104 CLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRFNIKLWKTFTDCFNCLPIAAI 163
Query: 187 LNQQFLCVHGGMSPEITSLDDIRKLDRFTEPPAFGPVCDLLWSDPSEDYGNEKTLEHYTH 246
++++ C HGG+SP++ S++ IR++ R T+ P G +CDLLWSDP +D ++ +
Sbjct: 164 VDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDTGLLCDLLWSDPDKD------VQGWGE 217
Query: 247 NTVRGCSYFYSYPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQATGFPSLITIFSAPN 306
N RG S+ + V +FL ++L I RAH+ + GY + K Q L+T+FSAPN
Sbjct: 218 ND-RGVSFTFGADVVSKFLNRHDLDLICRAHQVVEDGYEFFAKRQ------LVTLFSAPN 270
Query: 307 YLDVYNNKAAVLKYENNVM 325
Y ++N ++ + +M
Sbjct: 271 YCGEFDNAGGMMSVDETLM 289
>gi|4506005 protein phosphatase 1, catalytic subunit, beta isoform 1
[Homo sapiens]
Length = 327
Score = 216 bits (551), Expect = 3e-56
Identities = 102/259 (39%), Positives = 163/259 (62%), Gaps = 13/259 (5%)
Query: 67 ILRQEKTMIEVDAPITVCGDIHGQFFDLMKLFEVGGSPSNTRYLFLGDYVDRGYFSIECV 126
I + ++E++AP+ +CGDIHGQ+ DL++LFE GG P YLFLGDYVDRG S+E +
Sbjct: 44 IFLSQPILLELEAPLKICGDIHGQYTDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETI 103
Query: 127 LYLWSLKINHPKTLFLLRGNHECRHLTDYFTFKQECRIKYSEQVYDACMETFDCLPLAAL 186
L + KI +P+ FLLRGNHEC + + F EC+ +++ +++ + F+CLP+AA+
Sbjct: 104 CLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRFNIKLWKTFTDCFNCLPIAAI 163
Query: 187 LNQQFLCVHGGMSPEITSLDDIRKLDRFTEPPAFGPVCDLLWSDPSEDYGNEKTLEHYTH 246
++++ C HGG+SP++ S++ IR++ R T+ P G +CDLLWSDP +D ++ +
Sbjct: 164 VDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDTGLLCDLLWSDPDKD------VQGWGE 217
Query: 247 NTVRGCSYFYSYPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQATGFPSLITIFSAPN 306
N RG S+ + V +FL ++L I RAH+ + GY + K Q L+T+FSAPN
Sbjct: 218 ND-RGVSFTFGADVVSKFLNRHDLDLICRAHQVVEDGYEFFAKRQ------LVTLFSAPN 270
Query: 307 YLDVYNNKAAVLKYENNVM 325
Y ++N ++ + +M
Sbjct: 271 YCGEFDNAGGMMSVDETLM 289
>gi|57222565 protein phosphatase 2, catalytic subunit, beta isoform
[Homo sapiens]
Length = 309
Score = 215 bits (548), Expect = 7e-56
Identities = 117/286 (40%), Positives = 164/286 (57%), Gaps = 16/286 (5%)
Query: 51 RLEEEVALKIINDGAAILRQEKTMIEVDAPITVCGDIHGQFFDLMKLFEVGGSPSNTRYL 110
+L E + IL +E + EV P+TVCGD+HGQF DLM+LF +GG +T YL
Sbjct: 22 QLNENQVRTLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYL 81
Query: 111 FLGDYVDRGYFSIECVLYLWSLKINHPKTLFLLRGNHECRHLTDYFTFKQECRIKY-SEQ 169
F+GDYVDRGY+S+E V L +LK+ +P+ + +LRGNHE R +T + F EC KY +
Sbjct: 82 FMGDYVDRGYYSVETVTLLVALKVRYPERITILRGNHESRQITQVYGFYDECLRKYGNAN 141
Query: 170 VYDACMETFDCLPLAALLNQQFLCVHGGMSPEITSLDDIRKLDRFTEPPAFGPVCDLLWS 229
V+ + FD LPL AL++ Q C+HGG+SP I +LD IR LDR E P GP+CDLLWS
Sbjct: 142 VWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWS 201
Query: 230 DPSEDYGNEKTLEHYTHNTVRGCSYFYSYPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRK 289
DP + G + RG Y + F N L + RAH+ GY
Sbjct: 202 DPDDRGG--------WGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHD 253
Query: 290 SQATGFPSLITIFSAPNYLDVYNNKAAVLKYENNV-MNIRQFNCSP 334
+++TIFSAPNY N+AA+++ ++ + + QF+ +P
Sbjct: 254 R------NVVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQFDPAP 293
>gi|4758952 protein phosphatase 2, catalytic subunit, beta isoform
[Homo sapiens]
Length = 309
Score = 215 bits (548), Expect = 7e-56
Identities = 117/286 (40%), Positives = 164/286 (57%), Gaps = 16/286 (5%)
Query: 51 RLEEEVALKIINDGAAILRQEKTMIEVDAPITVCGDIHGQFFDLMKLFEVGGSPSNTRYL 110
+L E + IL +E + EV P+TVCGD+HGQF DLM+LF +GG +T YL
Sbjct: 22 QLNENQVRTLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYL 81
Query: 111 FLGDYVDRGYFSIECVLYLWSLKINHPKTLFLLRGNHECRHLTDYFTFKQECRIKY-SEQ 169
F+GDYVDRGY+S+E V L +LK+ +P+ + +LRGNHE R +T + F EC KY +
Sbjct: 82 FMGDYVDRGYYSVETVTLLVALKVRYPERITILRGNHESRQITQVYGFYDECLRKYGNAN 141
Query: 170 VYDACMETFDCLPLAALLNQQFLCVHGGMSPEITSLDDIRKLDRFTEPPAFGPVCDLLWS 229
V+ + FD LPL AL++ Q C+HGG+SP I +LD IR LDR E P GP+CDLLWS
Sbjct: 142 VWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWS 201
Query: 230 DPSEDYGNEKTLEHYTHNTVRGCSYFYSYPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRK 289
DP + G + RG Y + F N L + RAH+ GY
Sbjct: 202 DPDDRGG--------WGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHD 253
Query: 290 SQATGFPSLITIFSAPNYLDVYNNKAAVLKYENNV-MNIRQFNCSP 334
+++TIFSAPNY N+AA+++ ++ + + QF+ +P
Sbjct: 254 R------NVVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQFDPAP 293
>gi|4506027 protein phosphatase 4, catalytic subunit [Homo sapiens]
Length = 307
Score = 215 bits (547), Expect = 9e-56
Identities = 111/259 (42%), Positives = 158/259 (61%), Gaps = 15/259 (5%)
Query: 67 ILRQEKTMIEVDAPITVCGDIHGQFFDLMKLFEVGGSPSNTRYLFLGDYVDRGYFSIECV 126
IL +E + VD+P+TVCGDIHGQF+DL +LF VGG T YLF+GD+VDRG++S+E
Sbjct: 35 ILVEESNVQRVDSPVTVCGDIHGQFYDLKELFRVGGDVPETNYLFMGDFVDRGFYSVETF 94
Query: 127 LYLWSLKINHPKTLFLLRGNHECRHLTDYFTFKQECRIKY-SEQVYDACMETFDCLPLAA 185
L L +LK+ +P + L+RGNHE R +T + F EC KY S V+ C E FD L L+A
Sbjct: 95 LLLLALKVRYPDRITLIRGNHESRQITQVYGFYDECLRKYGSVTVWRYCTEIFDYLSLSA 154
Query: 186 LLNQQFLCVHGGMSPEITSLDDIRKLDRFTEPPAFGPVCDLLWSDPSEDYGNEKTLEHYT 245
+++ + CVHGG+SP I +LD IR +DR E P GP+CDLLWSDP + G
Sbjct: 155 IIDGKIFCVHGGLSPSIQTLDQIRTIDRKQEVPHDGPMCDLLWSDPEDTTG--------W 206
Query: 246 HNTVRGCSYFYSYPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQATGFPSLITIFSAP 305
+ RG Y + V +F N++ I RAH+ GY+ + +++T++SAP
Sbjct: 207 GVSPRGAGYLFGSDVVAQFNAANDIDMICRAHQLVMEGYKWHFNE------TVLTVWSAP 260
Query: 306 NYLDVYNNKAAVLKYENNV 324
NY N AA+L+ + ++
Sbjct: 261 NYCYRCGNVAAILELDEHL 279
>gi|4506017 protein phosphatase 2, catalytic subunit, alpha isoform
[Homo sapiens]
Length = 309
Score = 212 bits (540), Expect = 6e-55
Identities = 116/286 (40%), Positives = 163/286 (56%), Gaps = 16/286 (5%)
Query: 51 RLEEEVALKIINDGAAILRQEKTMIEVDAPITVCGDIHGQFFDLMKLFEVGGSPSNTRYL 110
+L E + IL +E + EV P+TVCGD+HGQF DLM+LF +GG +T YL
Sbjct: 22 QLSESQVKSLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYL 81
Query: 111 FLGDYVDRGYFSIECVLYLWSLKINHPKTLFLLRGNHECRHLTDYFTFKQECRIKY-SEQ 169
F+GDYVDRGY+S+E V L +LK+ + + + +LRGNHE R +T + F EC KY +
Sbjct: 82 FMGDYVDRGYYSVETVTLLVALKVRYRERITILRGNHESRQITQVYGFYDECLRKYGNAN 141
Query: 170 VYDACMETFDCLPLAALLNQQFLCVHGGMSPEITSLDDIRKLDRFTEPPAFGPVCDLLWS 229
V+ + FD LPL AL++ Q C+HGG+SP I +LD IR LDR E P GP+CDLLWS
Sbjct: 142 VWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWS 201
Query: 230 DPSEDYGNEKTLEHYTHNTVRGCSYFYSYPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRK 289
DP + G + RG Y + F N L + RAH+ GY
Sbjct: 202 DPDDRGG--------WGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHD 253
Query: 290 SQATGFPSLITIFSAPNYLDVYNNKAAVLKYENNV-MNIRQFNCSP 334
+++TIFSAPNY N+AA+++ ++ + + QF+ +P
Sbjct: 254 R------NVVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQFDPAP 293
>gi|5453958 protein phosphatase 5, catalytic subunit [Homo sapiens]
Length = 499
Score = 209 bits (531), Expect = 6e-54
Identities = 119/315 (37%), Positives = 176/315 (55%), Gaps = 25/315 (7%)
Query: 33 ENGKPKVDVLKNHLV---KEGRLEEEVALKIINDGAAILRQEKTMIEVDAP----ITVCG 85
E+GK + +K + + +L + A +I+ +L + T++E ITVCG
Sbjct: 182 EDGKVTISFMKELMQWYKDQKKLHRKCAYQILVQVKEVLSKLSTLVETTLKETEKITVCG 241
Query: 86 DIHGQFFDLMKLFEVGGSPSNTR-YLFLGDYVDRGYFSIECVLYLWSLKINHPKTLFLLR 144
D HGQF+DL+ +FE+ G PS T Y+F GD+VDRG FS+E +L L+ K+ +P LLR
Sbjct: 242 DTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLR 301
Query: 145 GNHECRHLTDYFTFKQECRIKYSEQVYDACMETFDCLPLAALLNQQFLCVHGGM-SPEIT 203
GNHE ++ + F+ E + KY+ Q+Y+ E F+ LPLA +N + L +HGG+ S +
Sbjct: 302 GNHETDNMNQIYGFEGEVKAKYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDGV 361
Query: 204 SLDDIRKLDRFTEPPAFGPVCDLLWSDPSEDYGNEKTLEHYTHNTVRGCSYFYSYPAVCE 263
+LDDIRK++R +PP GP+CDLLWSDP G + RG S +
Sbjct: 362 TLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNGRS--------ISKRGVSCQFGPDVTKA 413
Query: 264 FLQNNNLLSIIRAHEAQDAGYRMYRKSQATGFPSLITIFSAPNYLDVYNNKAAVLKYENN 323
FL+ NNL IIR+HE + GY + + +T+FSAPNY D NKA+ + + +
Sbjct: 414 FLEENNLDYIIRSHEVKAEGYEVAHGGRC------VTVFSAPNYCDQMGNKASYIHLQGS 467
Query: 324 VM--NIRQFNCSPHP 336
+ QF PHP
Sbjct: 468 DLRPQFHQFTAVPHP 482
>gi|45827798 protein phosphatase 1, catalytic subunit, alpha isoform
2 [Homo sapiens]
Length = 286
Score = 207 bits (527), Expect = 2e-53
Identities = 99/241 (41%), Positives = 154/241 (63%), Gaps = 13/241 (5%)
Query: 85 GDIHGQFFDLMKLFEVGGSPSNTRYLFLGDYVDRGYFSIECVLYLWSLKINHPKTLFLLR 144
GDIHGQ++DL++LFE GG P + YLFLGDYVDRG S+E + L + KI +P+ FLLR
Sbjct: 19 GDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLR 78
Query: 145 GNHECRHLTDYFTFKQECRIKYSEQVYDACMETFDCLPLAALLNQQFLCVHGGMSPEITS 204
GNHEC + + F EC+ +Y+ +++ + F+CLP+AA+++++ C HGG+SP++ S
Sbjct: 79 GNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQS 138
Query: 205 LDDIRKLDRFTEPPAFGPVCDLLWSDPSEDYGNEKTLEHYTHNTVRGCSYFYSYPAVCEF 264
++ IR++ R T+ P G +CDLLWSDP +D ++ + N RG S+ + V +F
Sbjct: 139 MEQIRRIMRPTDVPDQGLLCDLLWSDPDKD------VQGWGEND-RGVSFTFGAEVVAKF 191
Query: 265 LQNNNLLSIIRAHEAQDAGYRMYRKSQATGFPSLITIFSAPNYLDVYNNKAAVLKYENNV 324
L ++L I RAH+ + GY + K Q L+T+FSAPNY ++N A++ + +
Sbjct: 192 LHKHDLDLICRAHQVVEDGYEFFAKRQ------LVTLFSAPNYCGEFDNAGAMMSVDETL 245
Query: 325 M 325
M
Sbjct: 246 M 246
>gi|183603929 protein phosphatase 6, catalytic subunit isoform a
[Homo sapiens]
Length = 342
Score = 206 bits (524), Expect = 4e-53
Identities = 110/270 (40%), Positives = 157/270 (58%), Gaps = 16/270 (5%)
Query: 67 ILRQEKTMIEVDAPITVCGDIHGQFFDLMKLFEVGGSPSNTRYLFLGDYVDRGYFSIECV 126
+L +E + V P+TVCGDIHGQF+DL +LF GG +T Y+F+GD+VDRGY+S+E
Sbjct: 71 LLLEESNVQPVSTPVTVCGDIHGQFYDLCELFRTGGQVPDTNYIFMGDFVDRGYYSLETF 130
Query: 127 LYLWSLKINHPKTLFLLRGNHECRHLTDYFTFKQECRIKY-SEQVYDACMETFDCLPLAA 185
YL +LK P + LLRGNHE R +T + F EC+ KY + + C + FD L +AA
Sbjct: 131 TYLLALKAKWPDRITLLRGNHESRQITQVYGFYDECQTKYGNANAWRYCTKVFDMLTVAA 190
Query: 186 LLNQQFLCVHGGMSPEITSLDDIRKLDRFTEPPAFGPVCDLLWSDPSEDYGNEKTLEHYT 245
L+++Q LCVHGG+SP+I +LD IR ++R E P G CDL+WSDP ED
Sbjct: 191 LIDEQILCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSDP-EDVDTWAI----- 244
Query: 246 HNTVRGCSYFYSYPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQATGFPSLITIFSAP 305
+ RG + + EF+ NNL I RAH+ GY+ + L+T++SAP
Sbjct: 245 --SPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGYKFMFDEK------LVTVWSAP 296
Query: 306 NYLDVYNNKAAVLKYEN-NVMNIRQFNCSP 334
NY N A+++ +++ N + F P
Sbjct: 297 NYCYRCGNIASIMVFKDVNTREPKLFRAVP 326
>gi|4506029 protein phosphatase 6, catalytic subunit isoform b [Homo
sapiens]
Length = 305
Score = 206 bits (524), Expect = 4e-53
Identities = 110/270 (40%), Positives = 157/270 (58%), Gaps = 16/270 (5%)
Query: 67 ILRQEKTMIEVDAPITVCGDIHGQFFDLMKLFEVGGSPSNTRYLFLGDYVDRGYFSIECV 126
+L +E + V P+TVCGDIHGQF+DL +LF GG +T Y+F+GD+VDRGY+S+E
Sbjct: 34 LLLEESNVQPVSTPVTVCGDIHGQFYDLCELFRTGGQVPDTNYIFMGDFVDRGYYSLETF 93
Query: 127 LYLWSLKINHPKTLFLLRGNHECRHLTDYFTFKQECRIKY-SEQVYDACMETFDCLPLAA 185
YL +LK P + LLRGNHE R +T + F EC+ KY + + C + FD L +AA
Sbjct: 94 TYLLALKAKWPDRITLLRGNHESRQITQVYGFYDECQTKYGNANAWRYCTKVFDMLTVAA 153
Query: 186 LLNQQFLCVHGGMSPEITSLDDIRKLDRFTEPPAFGPVCDLLWSDPSEDYGNEKTLEHYT 245
L+++Q LCVHGG+SP+I +LD IR ++R E P G CDL+WSDP ED
Sbjct: 154 LIDEQILCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSDP-EDVDTWAI----- 207
Query: 246 HNTVRGCSYFYSYPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQATGFPSLITIFSAP 305
+ RG + + EF+ NNL I RAH+ GY+ + L+T++SAP
Sbjct: 208 --SPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGYKFMFDEK------LVTVWSAP 259
Query: 306 NYLDVYNNKAAVLKYEN-NVMNIRQFNCSP 334
NY N A+++ +++ N + F P
Sbjct: 260 NYCYRCGNIASIMVFKDVNTREPKLFRAVP 289
>gi|183603931 protein phosphatase 6, catalytic subunit isoform c
[Homo sapiens]
Length = 283
Score = 170 bits (430), Expect = 3e-42
Identities = 100/270 (37%), Positives = 141/270 (52%), Gaps = 38/270 (14%)
Query: 67 ILRQEKTMIEVDAPITVCGDIHGQFFDLMKLFEVGGSPSNTRYLFLGDYVDRGYFSIECV 126
+L +E + V P+TVCGDIHGQ GD+VDRGY+S+E
Sbjct: 34 LLLEESNVQPVSTPVTVCGDIHGQ----------------------GDFVDRGYYSLETF 71
Query: 127 LYLWSLKINHPKTLFLLRGNHECRHLTDYFTFKQECRIKYSE-QVYDACMETFDCLPLAA 185
YL +LK P + LLRGNHE R +T + F EC+ KY + C + FD L +AA
Sbjct: 72 TYLLALKAKWPDRITLLRGNHESRQITQVYGFYDECQTKYGNANAWRYCTKVFDMLTVAA 131
Query: 186 LLNQQFLCVHGGMSPEITSLDDIRKLDRFTEPPAFGPVCDLLWSDPSEDYGNEKTLEHYT 245
L+++Q LCVHGG+SP+I +LD IR ++R E P G CDL+WSDP ED
Sbjct: 132 LIDEQILCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSDP-EDVDTWAI----- 185
Query: 246 HNTVRGCSYFYSYPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQATGFPSLITIFSAP 305
+ RG + + EF+ NNL I RAH+ GY+ + L+T++SAP
Sbjct: 186 --SPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGYKFMFDEK------LVTVWSAP 237
Query: 306 NYLDVYNNKAAVLKYEN-NVMNIRQFNCSP 334
NY N A+++ +++ N + F P
Sbjct: 238 NYCYRCGNIASIMVFKDVNTREPKLFRAVP 267
>gi|23312374 protein phosphatase with EF hand calcium-binding domain
1 isoform 1b [Homo sapiens]
Length = 625
Score = 119 bits (297), Expect = 9e-27
Identities = 85/305 (27%), Positives = 142/305 (46%), Gaps = 38/305 (12%)
Query: 39 VDVLKNHLVKEGRLEEEVALKIINDGAAILRQEKTMIEVDAP----ITVCGDIHGQFFDL 94
+D+L ++ L L+++ + +L+Q + +T+CGD+HG+ DL
Sbjct: 121 IDLLLEAFKEQQILHAHYVLEVLFETKKVLKQMPNFTHIQTSPSKEVTICGDLHGKLDDL 180
Query: 95 MKLFEVGGSPSNTR-YLFLGDYVDRGYFSIECVLYLWSLKINHPKTLFLLRGNHECRHLT 153
+F G PS Y+F GD+VDRG SIE ++ L + +P L L RGNHE +
Sbjct: 181 FLIFYKNGLPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFMMN 240
Query: 154 DYFTFKQECRIKY---SEQVYDACMETFDCLPLAALLNQQFLCVHGGMSPEITSLDDIRK 210
+ F +E KY +++ E + LP+ +++ + L +HGG+S E T L+ + +
Sbjct: 241 LRYGFTKEILHKYKLHGKRILQILEEFYAWLPIGTIVDNEILVIHGGIS-ETTDLNLLHR 299
Query: 211 LDR-----FTEPPA-----------FGPVCDLLWSDPSEDYGNEKTLEHYTHNTVRGCSY 254
++R PP + D+LWSDP G NT RG
Sbjct: 300 VERNKMKSVLIPPTETNRDHDTDSKHNKIIDILWSDPRGKNG-------CFPNTCRGGGC 352
Query: 255 FYSYPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQATGFPSLITIFSAPNYLDVYNNK 314
++ + L L +IR+HE + GY + + ++TIFSA NY + +N+
Sbjct: 353 YFGPDVTSKILNKYQLKMLIRSHECKPEGYEICHDGK------VVTIFSASNYYEEGSNR 406
Query: 315 AAVLK 319
A +K
Sbjct: 407 GAYIK 411
>gi|23312380 protein phosphatase with EF hand calcium-binding domain
1 isoform 1 [Homo sapiens]
Length = 653
Score = 108 bits (269), Expect = 2e-23
Identities = 85/333 (25%), Positives = 143/333 (42%), Gaps = 66/333 (19%)
Query: 39 VDVLKNHLVKEGRLEEEVALKIINDGAAILRQEKTMIEVDAP----ITVCGDIHGQFFDL 94
+D+L ++ L L+++ + +L+Q + +T+CGD+HG+ DL
Sbjct: 121 IDLLLEAFKEQQILHAHYVLEVLFETKKVLKQMPNFTHIQTSPSKEVTICGDLHGKLDDL 180
Query: 95 MKLFEVGGSPSNTR-YLFLGDYVDRGYFSIECVLYLWSLKINHPKTLFLLRGNHECRHLT 153
+F G PS Y+F GD+VDRG SIE ++ L + +P L L RGNHE +
Sbjct: 181 FLIFYKNGLPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFMMN 240
Query: 154 DYFTFKQECRIKY---SEQVYDACMETFDCLPLAALLNQQFLCVHGGMSPEITSLDDIRK 210
+ F +E KY +++ E + LP+ +++ + L +HGG+S E T L+ + +
Sbjct: 241 LRYGFTKEILHKYKLHGKRILQILEEFYAWLPIGTIVDNEILVIHGGIS-ETTDLNLLHR 299
Query: 211 LDR-----FTEPPA---------------------------------------FGPVCDL 226
++R PP + + D+
Sbjct: 300 VERNKMKSVLIPPTETNRDHDTDSKHNKVGVTFNAHGRIKTNGSPTEHLTEHEWEQIIDI 359
Query: 227 LWSDPSEDYGNEKTLEHYTHNTVRGCSYFYSYPAVCEFLQNNNLLSIIRAHEAQDAGYRM 286
LWSDP G NT RG ++ + L L +IR+HE + GY +
Sbjct: 360 LWSDPRGKNG-------CFPNTCRGGGCYFGPDVTSKILNKYQLKMLIRSHECKPEGYEI 412
Query: 287 YRKSQATGFPSLITIFSAPNYLDVYNNKAAVLK 319
+ ++TIFSA NY + +N+ A +K
Sbjct: 413 CHDGK------VVTIFSASNYYEEGSNRGAYIK 439
>gi|239752750 PREDICTED: similar to protein phosphatase 2, catalytic
subunit, alpha [Homo sapiens]
Length = 384
Score = 98.2 bits (243), Expect = 2e-20
Identities = 70/248 (28%), Positives = 107/248 (43%), Gaps = 68/248 (27%)
Query: 60 IINDGAAILRQEKTMIEVDAPITVCGDIHGQFFDLMKLFEVGGSPSNTRYLFLGDYVDRG 119
+ + IL +E EV P+TV GD HGQ GDY+DRG
Sbjct: 180 LCKEAKEILTEESNAQEVWCPVTVSGDKHGQ----------------------GDYIDRG 217
Query: 120 YFSIECVLYLWSLKINHPKTLFLLRGNHECRHLTDYFTFKQECRIKYSEQVYDACMETFD 179
Y+SIE V+ L ++K+++ + + +L NHE R +T + +EC K+ D
Sbjct: 218 YYSIEIVMLLLAVKVSYHECVTILPRNHESRQITQVYHSYEECLRKHGNANGDG------ 271
Query: 180 CLPLAALLNQQFLCVHGGMSPEITSLDDIRKLDRFTEPPAFGPVCDLLWSDPSEDYGNEK 239
Q C+HGG+SP + +L IR L+ + P GP+ DLL+SDP +D+ +
Sbjct: 272 ----------QLFCLHGGLSPSVDTLHHIRTLNCLQKIPHEGPMGDLLYSDP-DDHDTPE 320
Query: 240 TLEHYTHNTVRGCSYFYSYPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQATGFPSLI 299
T H + L + RAH+ G+ +++
Sbjct: 321 TFNH-----------------------ASGLRLVSRAHQLVMVGHNWCHDW------NVV 351
Query: 300 TIFSAPNY 307
IFS PNY
Sbjct: 352 AIFSTPNY 359
>gi|239747318 PREDICTED: similar to protein phosphatase 2, catalytic
subunit, alpha [Homo sapiens]
Length = 254
Score = 98.2 bits (243), Expect = 2e-20
Identities = 70/248 (28%), Positives = 107/248 (43%), Gaps = 68/248 (27%)
Query: 60 IINDGAAILRQEKTMIEVDAPITVCGDIHGQFFDLMKLFEVGGSPSNTRYLFLGDYVDRG 119
+ + IL +E EV P+TV GD HGQ GDY+DRG
Sbjct: 59 LCKEAKEILTEESNAQEVWCPVTVSGDKHGQ----------------------GDYIDRG 96
Query: 120 YFSIECVLYLWSLKINHPKTLFLLRGNHECRHLTDYFTFKQECRIKYSEQVYDACMETFD 179
Y+SIE V+ L ++K+++ + + +L NHE R +T + +EC K+ D
Sbjct: 97 YYSIEIVMLLLAVKVSYHECVTILPRNHESRQITQVYHSYEECLRKHGNANGDG------ 150
Query: 180 CLPLAALLNQQFLCVHGGMSPEITSLDDIRKLDRFTEPPAFGPVCDLLWSDPSEDYGNEK 239
Q C+HGG+SP + +L IR L+ + P GP+ DLL+SDP +D+ +
Sbjct: 151 ----------QLFCLHGGLSPSVDTLHHIRTLNCLQKIPHEGPMGDLLYSDP-DDHDTPE 199
Query: 240 TLEHYTHNTVRGCSYFYSYPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQATGFPSLI 299
T H + L + RAH+ G+ +++
Sbjct: 200 TFNH-----------------------ASGLRLVSRAHQLVMVGHNWCHDW------NVV 230
Query: 300 TIFSAPNY 307
IFS PNY
Sbjct: 231 AIFSTPNY 238
>gi|239741140 PREDICTED: similar to protein phosphatase 2, catalytic
subunit, alpha [Homo sapiens]
Length = 254
Score = 98.2 bits (243), Expect = 2e-20
Identities = 70/248 (28%), Positives = 107/248 (43%), Gaps = 68/248 (27%)
Query: 60 IINDGAAILRQEKTMIEVDAPITVCGDIHGQFFDLMKLFEVGGSPSNTRYLFLGDYVDRG 119
+ + IL +E EV P+TV GD HGQ GDY+DRG
Sbjct: 59 LCKEAKEILTEESNAQEVWCPVTVSGDKHGQ----------------------GDYIDRG 96
Query: 120 YFSIECVLYLWSLKINHPKTLFLLRGNHECRHLTDYFTFKQECRIKYSEQVYDACMETFD 179
Y+SIE V+ L ++K+++ + + +L NHE R +T + +EC K+ D
Sbjct: 97 YYSIEIVMLLLAVKVSYHECVTILPRNHESRQITQVYHSYEECLRKHGNANGDG------ 150
Query: 180 CLPLAALLNQQFLCVHGGMSPEITSLDDIRKLDRFTEPPAFGPVCDLLWSDPSEDYGNEK 239
Q C+HGG+SP + +L IR L+ + P GP+ DLL+SDP +D+ +
Sbjct: 151 ----------QLFCLHGGLSPSVDTLHHIRTLNCLQKIPHEGPMGDLLYSDP-DDHDTPE 199
Query: 240 TLEHYTHNTVRGCSYFYSYPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQATGFPSLI 299
T H + L + RAH+ G+ +++
Sbjct: 200 TFNH-----------------------ASGLRLVSRAHQLVMVGHNWCHDW------NVV 230
Query: 300 TIFSAPNY 307
IFS PNY
Sbjct: 231 AIFSTPNY 238
>gi|23312386 serine/threonine protein phosphatase with EF-hand
motifs 2 [Homo sapiens]
Length = 753
Score = 98.2 bits (243), Expect = 2e-20
Identities = 55/137 (40%), Positives = 85/137 (62%), Gaps = 5/137 (3%)
Query: 81 ITVCGDIHGQFFDLMKLFEVGGSPSNTR-YLFLGDYVDRGYFSIECVLYLWSLKINHPKT 139
ITVCGD+HGQ DL+ +F G PS R Y+F GD+VDRG S+E ++ L++ + +PK
Sbjct: 174 ITVCGDLHGQLDDLIFIFYKNGLPSPERSYVFNGDFVDRGKDSVEILMILFAFMLVYPKE 233
Query: 140 LFLLRGNHECRHLTDYFTFKQECRIKY---SEQVYDACMETFDCLPLAALLNQQFLCVHG 196
L RGNHE + + F +E KY +++ + F LPLA L++++ L +HG
Sbjct: 234 FHLNRGNHEDHMVNLRYGFTKEVMNKYKVHGKEILRTLQDVFCWLPLATLIDEKVLILHG 293
Query: 197 GMSPEITSLDDIRKLDR 213
G+S +IT L+ + K++R
Sbjct: 294 GVS-DITDLELLDKIER 309
Score = 55.5 bits (132), Expect = 1e-07
Identities = 32/97 (32%), Positives = 49/97 (50%), Gaps = 13/97 (13%)
Query: 223 VCDLLWSDPSEDYGNEKTLEHYTHNTVRGCSYFYSYPAVCEFLQNNNLLSIIRAHEAQDA 282
V D+LWSDP G + NT+RG ++ + LQ N+ +IR+HE +
Sbjct: 441 VVDILWSDPMAQEGCKA-------NTIRGGGCYFGPDVTQQLLQKYNMQFLIRSHECKPE 493
Query: 283 GYRMYRKSQATGFPSLITIFSAPNYLDVYNNKAAVLK 319
GY + ++TIFSA NY +V +N+ A +K
Sbjct: 494 GYEFCHNRK------VLTIFSASNYYEVGSNRGAYVK 524
>gi|23312378 protein phosphatase with EF hand calcium-binding domain
1 isoform 3 [Homo sapiens]
Length = 591
Score = 91.3 bits (225), Expect = 2e-18
Identities = 70/289 (24%), Positives = 127/289 (43%), Gaps = 40/289 (13%)
Query: 39 VDVLKNHLVKEGRLEEEVALKIINDGAAILRQEKTMIEVDAP----ITVCGDIHGQFFDL 94
+D+L ++ L L+++ + +L+Q + +T+CGD+HG+ DL
Sbjct: 121 IDLLLEAFKEQQILHAHYVLEVLFETKKVLKQMPNFTHIQTSPSKEVTICGDLHGKLDDL 180
Query: 95 MKLFEVGGSPSNTR-YLFLGDYVDRGYFSIECVLYLWSLKINHPKTLFLLRGNHECRHLT 153
+F G PS Y+F GD+VDRG SIE ++ L + +P L L RGNHE +
Sbjct: 181 FLIFYKNGLPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFMMN 240
Query: 154 DYFTFKQECRIKY---SEQVYDACMETFDCLPLAALLNQQFLCVHGGMSPEITSLDDIRK 210
+ F +E KY +++ E + LP+ +++ + L +HGG+S E T L+ + +
Sbjct: 241 LRYGFTKEILHKYKLHGKRILQILEEFYAWLPIGTIVDNEILVIHGGIS-ETTDLNLLHR 299
Query: 211 LDRFTEPPAFGPVCDLLWSDPSEDYGNEKTLEHYTHNTVRGCSYFYSYPAVCEFLQNNNL 270
++R P + ++ N+ + H ++ N +
Sbjct: 300 VERNKMKSVLIPPTETNRDHDTDSKHNKVGVTFNAHGRIK---------------TNGSP 344
Query: 271 LSIIRAHEAQDAGYRMYRKSQATGFPSLITIFSAPNYLDVYNNKAAVLK 319
+ HE + ++TIFSA NY + +N+ A +K
Sbjct: 345 TEHLTEHE----------------WEQVVTIFSASNYYEEGSNRGAYIK 377
>gi|4506875 selectin L precursor [Homo sapiens]
Length = 372
Score = 30.8 bits (68), Expect = 3.1
Identities = 27/129 (20%), Positives = 49/129 (37%), Gaps = 13/129 (10%)
Query: 117 DRGYFSIECVLYLWSLKINHPKTLFLLRGNHECRHLTDYFTFKQECRIKYSEQVYDACME 176
D GY+ +C + + P+ G +C H F+F +C SE +E
Sbjct: 183 DVGYYGPQCQFVIQCEPLEAPEL-----GTMDCTHPLGNFSFSSQCAFSCSEGTNLTGIE 237
Query: 177 TFDCLPLAALLNQQFLC----VHGGMSPEITSLDDIRKLDRFTEPPAFGPVCDLLWSDPS 232
C P + + C +P++ ++ L F +F C + S+ +
Sbjct: 238 ETTCGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHPLASF----SFTSACTFICSEGT 293
Query: 233 EDYGNEKTL 241
E G +KT+
Sbjct: 294 ELIGKKKTI 302
>gi|187608577 CASP8 and FADD-like apoptosis regulator isoform 1
[Homo sapiens]
Length = 480
Score = 30.8 bits (68), Expect = 3.1
Identities = 15/37 (40%), Positives = 25/37 (67%), Gaps = 2/37 (5%)
Query: 35 GKPKVDVLKNHLVKEGRLEEEVALKIINDGAAILRQE 71
GKPK+ ++N++V EG+LE+ L++ DG A+ E
Sbjct: 350 GKPKMFFIQNYVVSEGQLEDSSLLEV--DGPAMKNVE 384
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.137 0.413
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,396,019
Number of Sequences: 37866
Number of extensions: 918725
Number of successful extensions: 1946
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 30
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 1838
Number of HSP's gapped (non-prelim): 37
length of query: 512
length of database: 18,247,518
effective HSP length: 107
effective length of query: 405
effective length of database: 14,195,856
effective search space: 5749321680
effective search space used: 5749321680
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.