Guide to the Human Genome
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Name: CFLAR Sequence: fasta or formatted (480aa) NCBI GI: 187608577
Description:

CASP8 and FADD-like apoptosis regulator isoform 1

Referenced in:

BCL2 Pathways, Caspases, and Programmed Cell Death

Other entries for this name:
alt mRNA [480aa] CASP8 and FADD-like apoptosis regulator isoform 1
alt prot [221aa] CASP8 and FADD-like apoptosis regulator isoform 2
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             4.0         19           2
 C cysteine            2.1         10           1
 D aspartate           6.5         31           1
 E glutamate           7.1         34           2
 F phenylalanine       3.3         16           2
 G glycine             5.0         24           2
 H histidine           3.1         15           2
 I isoleucine          4.8         23           2
 K lysine              7.9         38           2
 L leucine            14.2         68           2
 M methionine          3.1         15           1
 N asparagine          2.7         13           2
 P proline             3.3         16           2
 Q glutamine           5.4         26           2
 R arginine            6.2         30           2
 S serine              8.1         39           2
 T threonine           2.5         12           1
 V valine              6.5         31           2
 W tryptophan          0.6          3           1
 Y tyrosine            3.5         17           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   CASP8 and FADD-like apoptosis regulator isoform 1 [... 
CFLAR                 1.000   CASP8 and FADD-like apoptosis regulator isoform 1 [...
CFLAR                 0.394   CASP8 and FADD-like apoptosis regulator isoform 2 [...
CASP8                 0.122   caspase 8 isoform G precursor 
CASP8                 0.122   caspase 8 isoform B precursor 
CASP8                 0.117   caspase 8 isoform C precursor 
CASP8                 0.117   caspase 8 isoform C precursor 
CASP8                 0.101   caspase 8 isoform A precursor 
CASP10                0.091   caspase 10 isoform d preproprotein 
CASP10                0.089   caspase 10 isoform b preproprotein 
CASP10                0.085   caspase 10 isoform a preproprotein 
CASP8                 0.050   caspase 8 isoform E 
CASP3                 0.044   caspase 3 preproprotein 
CASP3                 0.044   caspase 3 preproprotein 
CASP2                 0.043   caspase 2 isoform 1 preproprotein 
CASP6                 0.043   caspase 6 isoform alpha preproprotein 
CASP7                 0.039   caspase 7 isoform delta 
CASP7                 0.039   caspase 7 isoform alpha 
CASP7                 0.039   caspase 7 isoform alpha precursor 
CASP9                 0.027   caspase 9 isoform alpha preproprotein 
CASP6                 0.027   caspase 6 isoform beta 
CASP5                 0.023   caspase 5 isoform f precursor 
CASP5                 0.023   caspase 5 isoform d 
CASP5                 0.023   caspase 5 isoform c 
CASP5                 0.023   caspase 5 isoform b precursor 
CASP5                 0.023   caspase 5 isoform a precursor 
CASP1                 0.020   caspase 1 isoform gamma precursor 
CASP1                 0.020   caspase 1 isoform alpha precursor 
CASP1                 0.020   caspase 1 isoform beta precursor 
CASP1                 0.020   caspase 1 isoform delta 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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