Search of human proteins with 21327701

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|21327701 TBP-associated factor 15 isoform 1 [Homo sapiens]
         (592 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|21327701 TBP-associated factor 15 isoform 1 [Homo sapiens]        1288   0.0  
gi|4507353 TBP-associated factor 15 isoform 2 [Homo sapiens]         1277   0.0  
gi|4826734 fusion (involved in t(12;16) in malignant liposarcoma...   407   e-113
gi|253970504 Ewing sarcoma breakpoint region 1 isoform 4 [Homo s...   355   5e-98
gi|253970502 Ewing sarcoma breakpoint region 1 isoform 3 [Homo s...   335   5e-92
gi|253970500 Ewing sarcoma breakpoint region 1 isoform 1 [Homo s...   335   5e-92
gi|4885225 Ewing sarcoma breakpoint region 1 isoform 2 [Homo sap...   335   7e-92
gi|55956899 keratin 9 [Homo sapiens]                                  157   3e-38
gi|14043070 heterogeneous nuclear ribonucleoprotein A1 isoform b...   147   3e-35
gi|34740329 heterogeneous nuclear ribonucleoprotein A3 [Homo sap...   144   2e-34
gi|57864582 hornerin [Homo sapiens]                                   133   5e-31
gi|62122917 filaggrin family member 2 [Homo sapiens]                  132   7e-31
gi|195972866 keratin 10 [Homo sapiens]                                122   7e-28
gi|109255251 loricrin [Homo sapiens]                                  120   3e-27
gi|109452587 family with sequence similarity 98, member B isofor...   116   7e-26
gi|14043072 heterogeneous nuclear ribonucleoprotein A2/B1 isofor...   114   2e-25
gi|4504447 heterogeneous nuclear ribonucleoprotein A2/B1 isoform...   114   2e-25
gi|56699482 hypothetical protein LOC25940 [Homo sapiens]              112   7e-25
gi|109148552 keratin 3 [Homo sapiens]                                 107   2e-23
gi|5803036 heterogeneous nuclear ribonucleoprotein A0 [Homo sapi...   102   1e-21
gi|4504445 heterogeneous nuclear ribonucleoprotein A1 isoform a ...   100   5e-21
gi|212549553 interleukin enhancer binding factor 3 isoform d [Ho...   100   6e-21
gi|24234750 interleukin enhancer binding factor 3 isoform a [Hom...   100   6e-21
gi|242117971 RNA binding motif protein, X-linked-like 1 [Homo sa...    99   1e-20
gi|21361809 RNA binding motif protein, X-linked-like 1 [Homo sap...    99   1e-20
gi|56699409 RNA binding motif protein, X-linked [Homo sapiens]         98   2e-20
gi|119395750 keratin 1 [Homo sapiens]                                  97   5e-20
gi|25777671 protein phosphatase 1, regulatory subunit 10 [Homo s...    96   7e-20
gi|47132620 keratin 2 [Homo sapiens]                                   96   9e-20
gi|58761498 heterogeneous nuclear ribonucleoprotein A1-like [Hom...    94   4e-19

>gi|21327701 TBP-associated factor 15 isoform 1 [Homo sapiens]
          Length = 592

 Score = 1288 bits (3334), Expect = 0.0
 Identities = 592/592 (100%), Positives = 592/592 (100%)

Query: 1   MSDSGSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQSQ 60
           MSDSGSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQSQ
Sbjct: 1   MSDSGSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQSQ 60

Query: 61  SGYSQSYGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQQS 120
           SGYSQSYGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQQS
Sbjct: 61  SGYSQSYGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQQS 120

Query: 121 GYDQHQGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSRYGEDNRGYGGS 180
           GYDQHQGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSRYGEDNRGYGGS
Sbjct: 121 GYDQHQGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSRYGEDNRGYGGS 180

Query: 181 QGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDADSESDNSDNNTIFVQG 240
           QGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDADSESDNSDNNTIFVQG
Sbjct: 181 QGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDADSESDNSDNNTIFVQG 240

Query: 241 LGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATVSFDDPPSAKAAI 300
           LGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATVSFDDPPSAKAAI
Sbjct: 241 LGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATVSFDDPPSAKAAI 300

Query: 301 DWFDGKEFHGNIIKVSFATRRPEFMRGGGSGGGRRGRGGYRGRGGFQGRGGDPKSGDWVC 360
           DWFDGKEFHGNIIKVSFATRRPEFMRGGGSGGGRRGRGGYRGRGGFQGRGGDPKSGDWVC
Sbjct: 301 DWFDGKEFHGNIIKVSFATRRPEFMRGGGSGGGRRGRGGYRGRGGFQGRGGDPKSGDWVC 360

Query: 361 PNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGG 420
           PNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGG
Sbjct: 361 PNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGG 420

Query: 421 DRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYG 480
           DRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYG
Sbjct: 421 DRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYG 480

Query: 481 GDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSG 540
           GDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSG
Sbjct: 481 GDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSG 540

Query: 541 YGGDRSGGYGGDRSGGGYGGDRGGGYGGDRGGYGGKMGGRNDYRNDQRNRPY 592
           YGGDRSGGYGGDRSGGGYGGDRGGGYGGDRGGYGGKMGGRNDYRNDQRNRPY
Sbjct: 541 YGGDRSGGYGGDRSGGGYGGDRGGGYGGDRGGYGGKMGGRNDYRNDQRNRPY 592


>gi|4507353 TBP-associated factor 15 isoform 2 [Homo sapiens]
          Length = 589

 Score = 1277 bits (3305), Expect = 0.0
 Identities = 589/592 (99%), Positives = 589/592 (99%), Gaps = 3/592 (0%)

Query: 1   MSDSGSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQSQ 60
           MSDSGSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQS 
Sbjct: 1   MSDSGSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQS- 59

Query: 61  SGYSQSYGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQQS 120
             YSQSYGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQQS
Sbjct: 60  --YSQSYGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQQS 117

Query: 121 GYDQHQGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSRYGEDNRGYGGS 180
           GYDQHQGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSRYGEDNRGYGGS
Sbjct: 118 GYDQHQGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSRYGEDNRGYGGS 177

Query: 181 QGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDADSESDNSDNNTIFVQG 240
           QGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDADSESDNSDNNTIFVQG
Sbjct: 178 QGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDADSESDNSDNNTIFVQG 237

Query: 241 LGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATVSFDDPPSAKAAI 300
           LGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATVSFDDPPSAKAAI
Sbjct: 238 LGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATVSFDDPPSAKAAI 297

Query: 301 DWFDGKEFHGNIIKVSFATRRPEFMRGGGSGGGRRGRGGYRGRGGFQGRGGDPKSGDWVC 360
           DWFDGKEFHGNIIKVSFATRRPEFMRGGGSGGGRRGRGGYRGRGGFQGRGGDPKSGDWVC
Sbjct: 298 DWFDGKEFHGNIIKVSFATRRPEFMRGGGSGGGRRGRGGYRGRGGFQGRGGDPKSGDWVC 357

Query: 361 PNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGG 420
           PNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGG
Sbjct: 358 PNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGG 417

Query: 421 DRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYG 480
           DRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYG
Sbjct: 418 DRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYG 477

Query: 481 GDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSG 540
           GDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSG
Sbjct: 478 GDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSG 537

Query: 541 YGGDRSGGYGGDRSGGGYGGDRGGGYGGDRGGYGGKMGGRNDYRNDQRNRPY 592
           YGGDRSGGYGGDRSGGGYGGDRGGGYGGDRGGYGGKMGGRNDYRNDQRNRPY
Sbjct: 538 YGGDRSGGYGGDRSGGGYGGDRGGGYGGDRGGYGGKMGGRNDYRNDQRNRPY 589


>gi|4826734 fusion (involved in t(12;16) in malignant liposarcoma)
           [Homo sapiens]
          Length = 526

 Score =  407 bits (1046), Expect = e-113
 Identities = 267/522 (51%), Positives = 299/522 (57%), Gaps = 89/522 (17%)

Query: 15  QSYSTYGNPGSQGYGQAS------QSYSGYGQTTDSS-YGQNYSGYSSYGQSQ-SGYS-- 64
           QSY  Y     QGY Q S      QSYSGY Q+TD+S YGQ  S YSSYGQSQ +GY   
Sbjct: 12  QSYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTDTSGYGQ--SSYSSYGQSQNTGYGTQ 69

Query: 65  ---QSYG-----GYENQKQSSYSQQ-PYNNQGQQQNMES-SGSQG--GRAPSYDQPDY-- 110
              Q YG     G     QSSY QQ  Y   GQQ    S SGS G   ++ SY QP    
Sbjct: 70  STPQGYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGS 129

Query: 111 --------GQQDSYDQQSGYDQHQGSYDEQSNYDQQH---------DSYSQNQQSYHS-- 151
                   GQQ SY QQ  Y+  QG Y +Q+ Y+             +Y Q+Q S  S  
Sbjct: 130 YSQQPSYGGQQQSYGQQQSYNPPQG-YGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGG 188

Query: 152 -QRENYSHHTQDDRRDVSRYGEDN---RGYGGSQGGG--------RGRGGYDKDGRGPMT 199
                Y +  Q        YG+ +   RG GGS GGG        R  GGY+  GRG   
Sbjct: 189 GSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGGGGGYNRSSGGYEPRGRGGGR 248

Query: 200 GSSGG----DRGGFKNFGGHRDYGPRTDADSESDNSDNNTIFVQGLGEGVSTDQVGEFFK 255
           G  GG    DRGGF  FGG RD G R   DSE DNSDNNTIFVQGLGE V+ + V ++FK
Sbjct: 249 GGRGGMGGSDRGGFNKFGGPRDQGSR--HDSEQDNSDNNTIFVQGLGENVTIESVADYFK 306

Query: 256 QIGIIKTNKKTGKPMINLYTDKDTGKPKGEATVSFDDPPSAKAAIDWFDGKEFHGNIIKV 315
           QIGIIKTNKKTG+PMINLYTD++TGK KGEATVSFDDPPSAKAAIDWFDGKEF GN IKV
Sbjct: 307 QIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSFDDPPSAKAAIDWFDGKEFSGNPIKV 366

Query: 316 SFATRRPEFMRGGGSGGGRRGRGGYRGRGGF-------QGRGGDP----------KSGDW 358
           SFATRR +F RGGG+G G RGRGG  GRGG+        GRGG P          ++GDW
Sbjct: 367 SFATRRADFNRGGGNGRGGRGRGGPMGRGGYGGGGSGGGGRGGFPSGGGGGGGQQRAGDW 426

Query: 359 VCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGRGGRGG-DRGG 417
            CPNP+C NMNF+ RN CNQC  P+P+   P GG   G   GG  G   RGGRGG DRGG
Sbjct: 427 KCPNPTCENMNFSWRNECNQCKAPKPDG--PGGGP-GGSHMGGNYGDDRRGGRGGYDRGG 483

Query: 418 YGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDR 459
           Y G   GG  GG R   GG  GDR G G G   S G +  DR
Sbjct: 484 YRG--RGGDRGGFRGGRGG--GDRGGFGPGKMDSRGEHRQDR 521



 Score =  111 bits (277), Expect = 2e-24
 Identities = 85/225 (37%), Positives = 98/225 (43%), Gaps = 33/225 (14%)

Query: 385 EDSRPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGY----SGD 440
           + S  S G  +  GYG +   +G G  GG    YG  +S     G +SS  GY    +  
Sbjct: 52  QSSYSSYGQSQNTGYGTQSTPQGYGSTGG----YGSSQSSQSSYGQQSSYPGYGQQPAPS 107

Query: 441 RSGGGYGGDRSGGGYGGDRGGGY------GGDRGG-----GYGGDRGGG----YGGDRGG 485
            + G YG       YG  + G Y      GG +        Y   +G G    Y    GG
Sbjct: 108 STSGSYGSSSQSSSYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGG 167

Query: 486 YGGDRGGG-YGGDRGGY---GGDRGGYGGDRGGYGGDRGGYG----GDRSRGGYGGDRGG 537
            GG  GGG YG D+      GG  GGYG      GG  GGYG    G R RGG GG  GG
Sbjct: 168 GGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGG 227

Query: 538 GSGYGGDRSGGYGGDRSGGGYGGDRGGGYGGDRGGYGGKMGGRND 582
           G G     SGGY     GGG GG RGG  G DRGG+  K GG  D
Sbjct: 228 GGGGYNRSSGGYEPRGRGGGRGG-RGGMGGSDRGGF-NKFGGPRD 270



 Score =  106 bits (264), Expect = 7e-23
 Identities = 79/224 (35%), Positives = 98/224 (43%), Gaps = 33/224 (14%)

Query: 328 GGSGGGRRGRGGYRGRGGFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDS 387
           GG G  +  +  Y  +  + G G  P       P+ + G+   + ++S            
Sbjct: 79  GGYGSSQSSQSSYGQQSSYPGYGQQP------APSSTSGSYGSSSQSS------------ 120

Query: 388 RPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYG 447
             S G  +   Y  +  Y G+    G +  Y   +  G      SS GG  G   GG YG
Sbjct: 121 --SYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYG 178

Query: 448 GDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGG-DRGGYG-GDRGGGYGGDRGGYGGDR 505
            D+S    GG  GGGYG     G GG   GGYG  DRGG G G  GGG GG  GGY    
Sbjct: 179 QDQSSMSSGGGSGGGYGNQDQSGGGGS--GGYGQQDRGGRGRGGSGGGGGGGGGGYNRSS 236

Query: 506 GGYGGDRGGYGGDRGGYGGDRSRGGYGG-DRGGGSGYGGDRSGG 548
           GGY  +  G GG RGG      RGG GG DRGG + +GG R  G
Sbjct: 237 GGY--EPRGRGGGRGG------RGGMGGSDRGGFNKFGGPRDQG 272



 Score = 94.7 bits (234), Expect = 2e-19
 Identities = 70/158 (44%), Positives = 77/158 (48%), Gaps = 46/158 (29%)

Query: 474 DRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRG---- 529
           +RGGG G  RGG G  RGG  G  RGGYGG   G GG RGG+    GG GG +  G    
Sbjct: 376 NRGGGNG--RGGRG--RGGPMG--RGGYGGGGSG-GGGRGGFPSGGGGGGGQQRAGDWKC 428

Query: 530 -------------------------GYGGDRGG---GSGYGGDRSGGYGG-DRS-----G 555
                                    G GG  GG   G  YG DR GG GG DR      G
Sbjct: 429 PNPTCENMNFSWRNECNQCKAPKPDGPGGGPGGSHMGGNYGDDRRGGRGGYDRGGYRGRG 488

Query: 556 GGYGGDRGGGYGGDRGGYG-GKMGGRNDYRNDQRNRPY 592
           G  GG RGG  GGDRGG+G GKM  R ++R D+R RPY
Sbjct: 489 GDRGGFRGGRGGGDRGGFGPGKMDSRGEHRQDRRERPY 526



 Score = 63.5 bits (153), Expect = 5e-10
 Identities = 91/335 (27%), Positives = 130/335 (38%), Gaps = 66/335 (19%)

Query: 114 DSYDQQSGYDQHQGSYDEQ--SNYDQQHDS-YSQNQQSYHSQRENYSHHTQDDRRDVSRY 170
           + Y QQ+   Q  G+Y  Q    Y QQ    Y Q   S +SQ  + S + Q      S Y
Sbjct: 4   NDYTQQA--TQSYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTDTSGYGQS---SYSSY 58

Query: 171 GE-DNRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDADSESD 229
           G+  N GY G+Q   +G G     G    + SS G +  +  +G  +   P + + S   
Sbjct: 59  GQSQNTGY-GTQSTPQGYGSTGGYGSSQSSQSSYGQQSSYPGYG--QQPAPSSTSGSYGS 115

Query: 230 NSDNNTIFVQGLGEGVSTDQVGEFFKQIGIIKT-NKKTGKPMINLYTDKDTGKPKGEATV 288
           +S +++      G        G   +  G  ++ N   G    N Y     G   G    
Sbjct: 116 SSQSSSYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGG 175

Query: 289 SFDDPPSAKAAIDWFDGKEFHGNIIKVSFATRRPEFMRGGGSGG-GRRGRGGYRGRGGFQ 347
           ++    S+ ++     G   +GN           +   GGGSGG G++ RGG RGRGG  
Sbjct: 176 NYGQDQSSMSSGGGSGGG--YGN----------QDQSGGGGSGGYGQQDRGG-RGRGGSG 222

Query: 348 GRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRG 407
           G GG    G                              +R SGG +  RG GG RG  G
Sbjct: 223 GGGGGGGGG-----------------------------YNRSSGG-YEPRGRGGGRG--G 250

Query: 408 RGGRGG-DRGGYGGDRSGGGYGGDRSSGGGYSGDR 441
           RGG GG DRGG+        +GG R  G  +  ++
Sbjct: 251 RGGMGGSDRGGF------NKFGGPRDQGSRHDSEQ 279



 Score = 60.5 bits (145), Expect = 4e-09
 Identities = 55/206 (26%), Positives = 63/206 (30%), Gaps = 34/206 (16%)

Query: 418 YGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGG 477
           YG   +  G G  + S   Y G +S  GY       GYG      YG  +  GYG     
Sbjct: 14  YGAYPTQPGQGYSQQSSQPY-GQQSYSGYSQSTDTSGYGQSSYSSYGQSQNTGYGTQSTP 72

Query: 478 GYGGDRGGYGGDRGG-----------GYG------GDRGGYGGDR--GGYGGDRGGYGGD 518
              G  GGYG  +             GYG         G YG       YG  + G    
Sbjct: 73  QGYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQ 132

Query: 519 RGGYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDR--------------GG 564
           +  YGG +   G         GYG            GGG GG                GG
Sbjct: 133 QPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGG 192

Query: 565 GYGGDRGGYGGKMGGRNDYRNDQRNR 590
           GYG      GG  GG        R R
Sbjct: 193 GYGNQDQSGGGGSGGYGQQDRGGRGR 218



 Score = 38.9 bits (89), Expect = 0.013
 Identities = 25/53 (47%), Positives = 29/53 (54%), Gaps = 7/53 (13%)

Query: 525 DRSRGGYGGDRGGGSGYGGDRS-GGYGGDRSGGGYGGDRGGGYGGDRGGYGGK 576
           D +RGG  G+  GG G GG    GGYGG    GG GG   GG+    GG GG+
Sbjct: 374 DFNRGG--GNGRGGRGRGGPMGRGGYGG----GGSGGGGRGGFPSGGGGGGGQ 420



 Score = 33.5 bits (75), Expect = 0.56
 Identities = 18/36 (50%), Positives = 20/36 (55%), Gaps = 1/36 (2%)

Query: 544 DRSGGYGGDRSGGGYGGDRG-GGYGGDRGGYGGKMG 578
           D + G G  R G G GG  G GGYGG   G GG+ G
Sbjct: 374 DFNRGGGNGRGGRGRGGPMGRGGYGGGGSGGGGRGG 409


>gi|253970504 Ewing sarcoma breakpoint region 1 isoform 4 [Homo
           sapiens]
          Length = 600

 Score =  355 bits (912), Expect = 5e-98
 Identities = 248/605 (40%), Positives = 306/605 (50%), Gaps = 129/605 (21%)

Query: 2   SDSGSYGQSGGEQQSYSTYGNPGSQGYGQAS-----QSYSGYGQTTDSSYGQ-------N 49
           +D  +Y Q+   QQ YS Y    +QGY Q +     QSY  YGQ TD SY Q        
Sbjct: 4   TDYSTYSQAAA-QQGYSAYTAQPTQGYAQTTQAYGQQSYGTYGQPTDVSYTQAQTTATYG 62

Query: 50  YSGY-SSYGQSQSGYS-----QSY---------GGYEN------------QKQSSYSQQP 82
            + Y +SYGQ  +GY+     Q+Y         G Y+               QS+Y  QP
Sbjct: 63  QTAYATSYGQPPTGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAAQSAYGTQP 122

Query: 83  -YNNQGQQQNMESSGSQGGRAP-SYDQPDYGQQDSYDQQSGYDQHQGSYDEQSNYDQ--- 137
            Y   GQQ    +  S     P SYDQ  Y QQ++Y Q S Y Q Q SY +QS+Y Q   
Sbjct: 123 AYPAYGQQPAATAPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQ-QSSYGQQSSYGQQPP 181

Query: 138 -----QHDSYSQNQQSYHSQRENY---SHHTQDDRRDVSRYGE---------DNRGYGGS 180
                Q  SYSQ    Y  Q  +Y   S   QD    +  YG+         +NR   G 
Sbjct: 182 TSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSMSGP 241

Query: 181 QGGGRGRGGYDKDG--RGPMTGSSG-----GDRGGFKNFGGHRDYGPRTDADSESD---N 230
              GRGRGG+D+ G  RG   G  G     G+RGGF   GG  D GP  D     D   +
Sbjct: 242 DNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDPDED 301

Query: 231 SDNNTIFVQGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATVSF 290
           SDN+ I+VQGL + V+ D + +FFKQ G++K NK+TG+PMI++Y DK+TGKPKG+ATVS+
Sbjct: 302 SDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSY 361

Query: 291 DDPPSAKAAIDWFDGKEFHGNIIKVSFATRRPEF--MRGG-------------------- 328
           +DPP+AKAA++WFDGK+F G+ +KVS A ++P    MRGG                    
Sbjct: 362 EDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGP 421

Query: 329 GSGGGRRGRGGYRG--RGGFQGRG-----GDP--------KSGDWVCPNPSCGNMNFARR 373
           G  GG  GR G RG  RGGF  RG     G+P        ++GDW CPNP CGN NFA R
Sbjct: 422 GGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWR 481

Query: 374 NSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSS 433
             CNQC  P+PE   P         +    G RGRGG GG RGG GG    GG GG    
Sbjct: 482 TECNQCKAPKPEGFLPP-------PFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGG--MF 532

Query: 434 GGGYSGDRSG--GGYGGDRSGGGYGGDRGGGYGGDRG------GGYGGDRGGGYGGDRGG 485
            GG  GDR G  GG G DR  GG+GG R GG GG  G      GG  G RGG    D+G 
Sbjct: 533 RGGRGGDRGGFRGGRGMDR--GGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGKMDKGE 590

Query: 486 YGGDR 490
           +  +R
Sbjct: 591 HRQER 595



 Score =  306 bits (783), Expect = 5e-83
 Identities = 241/660 (36%), Positives = 299/660 (45%), Gaps = 178/660 (26%)

Query: 14  QQSYSTYGNPGSQGYGQASQSYSGYGQTT-DSSYGQNYSGYSS------YGQSQSGYSQS 66
           QQSY TYG P    Y QA Q+ + YGQT   +SYGQ  +GY++      Y Q   GY   
Sbjct: 38  QQSYGTYGQPTDVSYTQA-QTTATYGQTAYATSYGQPPTGYTTPTAPQAYSQPVQGYGT- 95

Query: 67  YGGYENQK------------QSSYSQQP-YNNQGQQQNMESSGSQGGRAP-SYDQPDYGQ 112
            G Y+               QS+Y  QP Y   GQQ    +  S     P SYDQ  Y Q
Sbjct: 96  -GAYDTTTATVTTTQASYAAQSAYGTQPAYPAYGQQPAATAPTSYSSTQPTSYDQSSYSQ 154

Query: 113 QDSYDQQSGYDQHQGSYDEQSNYDQQHD--------SYSQNQQSYHSQRENYSHHT---Q 161
           Q++Y Q S Y Q Q SY +QS+Y QQ          SYSQ    Y  Q  +Y   +   Q
Sbjct: 155 QNTYGQPSSYGQ-QSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQ 213

Query: 162 DDRRDVSRYGEDNRGYGG-----SQGG----GRGRGGYDKDG--RGPMTGSSGG-----D 205
           D    +  YG+++ G+ G     S  G    GRGRGG+D+ G  RG   G  GG     +
Sbjct: 214 DHPSSMGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGE 273

Query: 206 RGGFKNFGGHRDYGPRTDADSESD---NSDNNTIFVQGLGEGVSTDQVGEFFKQIGIIKT 262
           RGGF   GG  D GP  D     D   +SDN+ I+VQGL + V+ D + +FFKQ G++K 
Sbjct: 274 RGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKM 333

Query: 263 NKKTGKPMINLYTDKDTGKPKGEATVSFDDPPSAKAAIDWFDGKEFHGNIIKVSFATRRP 322
           NK+TG+PMI++Y DK+TGKPKG+ATVS++DPP+AKAA++WFDGK+F G+ +KVS A ++P
Sbjct: 334 NKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKP 393

Query: 323 EFMRGGGSGGGRRGRGGYRGRGGFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEP 382
                 G    R GRG                                           P
Sbjct: 394 PMNSMRGGLPPREGRG------------------------------------------MP 411

Query: 383 RPEDSRPSGGDFRGRGYGGERGYRGR-GGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDR 441
            P    P G        GG  G  GR GGRGGDRGG+      G  G    SGGG    R
Sbjct: 412 PPLRGGPGGP-------GGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNP--SGGGNVQHR 462

Query: 442 SGGGYGGDRSGGGY---------------------------GGDRGGGYGGDRGGGYGG- 473
           +G     +   G                             GGDRG G  G   GG GG 
Sbjct: 463 AGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGL 522

Query: 474 -DRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGYG 532
            DRGG  G  RGG GGDRGG     RGG G DRGG+GG R               RGG G
Sbjct: 523 MDRGGPGGMFRGGRGGDRGGF----RGGRGMDRGGFGGGR---------------RGGPG 563

Query: 533 GDRGGGSGYGGDRSGGYGGDRSGGGYGGDRGGGYGGDRGGYGGKMGGRNDYRNDQRNRPY 592
           G  G      G R GG GG                       GKM  + ++R ++R+RPY
Sbjct: 564 GPPGPLMEQMGGRRGGRGGP----------------------GKM-DKGEHRQERRDRPY 600


>gi|253970502 Ewing sarcoma breakpoint region 1 isoform 3 [Homo
           sapiens]
          Length = 655

 Score =  335 bits (860), Expect = 5e-92
 Identities = 228/553 (41%), Positives = 283/553 (51%), Gaps = 95/553 (17%)

Query: 12  GEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQSQSGYSQSYGGYE 71
           G Q +Y  YG    Q    A        + T++S  Q+ +G   Y Q   GY QS   Y 
Sbjct: 119 GTQPAYPAYGQ---QPAATAPTRPQDGNKPTETSQPQSSTG--GYNQPSLGYGQSNYSYP 173

Query: 72  NQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQQSGYDQHQGSYDE 131
            Q   SY  QP            S +Q     SYDQ  Y QQ++Y Q S Y Q Q SY +
Sbjct: 174 -QVPGSYPMQPVTAPPSYPPTSYSSTQ---PTSYDQSSYSQQNTYGQPSSYGQ-QSSYGQ 228

Query: 132 QSNYDQQHD--------SYSQNQQSYHSQRENYSHHT---QDDRRDVSRYGEDNRGYGG- 179
           QS+Y QQ          SYSQ    Y  Q  +Y   +   QD    +  YG+++ G+ G 
Sbjct: 229 QSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGP 288

Query: 180 ----SQGG----GRGRGGYDKDG--RGPMTGSSGG----DRGGFKNFGGHRDYGPRTDAD 225
               S  G    GRGRGG+D+ G  RG   G  GG    +RGGF   GG  D GP  D  
Sbjct: 289 GENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGAGERGGFNKPGGPMDEGPDLDLG 348

Query: 226 SESD---NSDNNTIFVQGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKP 282
              D   +SDN+ I+VQGL + V+ D + +FFKQ G++K NK+TG+PMI++Y DK+TGKP
Sbjct: 349 PPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKP 408

Query: 283 KGEATVSFDDPPSAKAAIDWFDGKEFHGNIIKVSFATRRPEF--MRGG------------ 328
           KG+ATVS++DPP+AKAA++WFDGK+F G+ +KVS A ++P    MRGG            
Sbjct: 409 KGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPP 468

Query: 329 --------GSGGGRRGRGGYRG--RGGFQGRG-----GDP--------KSGDWVCPNPSC 365
                   G  GG  GR G RG  RGGF  RG     G+P        ++GDW CPNP C
Sbjct: 469 LRGGPGGPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGC 528

Query: 366 GNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRSGG 425
           GN NFA R  CNQC  P+PE   P         +    G RGRGG GG RGG GG    G
Sbjct: 529 GNQNFAWRTECNQCKAPKPEGFLPP-------PFPPPGGDRGRGGPGGMRGGRGGLMDRG 581

Query: 426 GYGGDRSSGGGYSGDRSG--GGYGGDRSGGGYGGDRGGGYGGDRG------GGYGGDRGG 477
           G GG     GG  GDR G  GG G DR  GG+GG R GG GG  G      GG  G RGG
Sbjct: 582 GPGG--MFRGGRGGDRGGFRGGRGMDR--GGFGGGRRGGPGGPPGPLMEQMGGRRGGRGG 637

Query: 478 GYGGDRGGYGGDR 490
               D+G +  +R
Sbjct: 638 PGKMDKGEHRQER 650



 Score =  114 bits (286), Expect = 2e-25
 Identities = 185/699 (26%), Positives = 250/699 (35%), Gaps = 155/699 (22%)

Query: 2   SDSGSYGQSGGEQQSYSTYGNPGSQGYGQASQ-----SYSGYGQTTDSSYGQNYSGYSSY 56
           +D  +Y Q+   QQ YS Y    +QGY Q +Q     SY  YGQ TD SY Q  +  ++Y
Sbjct: 4   TDYSTYSQAAA-QQGYSAYTAQPTQGYAQTTQAYGQQSYGTYGQPTDVSYTQAQTT-ATY 61

Query: 57  GQSQSGYSQSYGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSY 116
           GQ+   Y+ SYG    Q  + Y+  P   Q   Q ++  G+  G   +        Q SY
Sbjct: 62  GQT--AYATSYG----QPPTGYTT-PTAPQAYSQPVQGYGT--GAYDTTTATVTTTQASY 112

Query: 117 DQQSGYDQHQGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSRYGEDNRG 176
             QS Y    G+      Y QQ  + +  +     Q  N    T   +     Y + + G
Sbjct: 113 AAQSAY----GTQPAYPAYGQQPAATAPTRP----QDGNKPTETSQPQSSTGGYNQPSLG 164

Query: 177 YGGSQGG-GRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDADSESDNSDNNT 235
           YG S     +  G Y      P+T                  Y P + + ++  + D ++
Sbjct: 165 YGQSNYSYPQVPGSYPMQ---PVTAPPS--------------YPPTSYSSTQPTSYDQSS 207

Query: 236 IFVQGL-GEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDT-----GKPKGEATVS 289
              Q   G+  S  Q   + +Q    +    +  P    Y+   +         G+ +  
Sbjct: 208 YSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSF 267

Query: 290 FDDPPSAKAAIDWFDGKEFHGNIIKVSFA------TRRPEFMRGG----GSGGGRRG--- 336
             D PS+        G  F G     S +        R  F RGG    G GGGR G   
Sbjct: 268 RQDHPSSMGVYGQESGG-FSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGA 326

Query: 337 --RGGYRGRGGFQGRGGDPKSGDWVCPNPS--------------------------CGNM 368
             RGG+   GG    G D   G  V P+                            CG +
Sbjct: 327 GERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVV 386

Query: 369 NFARRNSCNQCNEPRPEDSRPSGGD-----------------FRGRGYGGER-------- 403
              +R      +    +++    GD                 F G+ + G +        
Sbjct: 387 KMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARK 446

Query: 404 ---------GYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGG 454
                    G   R GRG      GG    GG GG     GG  GDR G    G R  G 
Sbjct: 447 KPPMNSMRGGLPPREGRGMPPPLRGGPGGPGGPGGPMGRMGGRGGDRGGFPPRGPR--GS 504

Query: 455 YGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGY--------GGDRG 506
            G   GGG    R G +     G  G     +  +          G+        GGDRG
Sbjct: 505 RGNPSGGGNVQHRAGDWQCPNPG-CGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRG 563

Query: 507 GYGGDRGGYGGDRGGYGGDRSRGGYGG-DRGGGSGYGGDRSGGYGGDRSGGGYGGDRGGG 565
                RGG GG RGG GG   RGG GG  RGG  G  G   GG G DR  GG+GG R GG
Sbjct: 564 -----RGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRGGFRGGRGMDR--GGFGGGRRGG 616

Query: 566 YGGDRG----GYGGKMGGR--------NDYRNDQRNRPY 592
            GG  G      GG+ GGR         ++R ++R+RPY
Sbjct: 617 PGGPPGPLMEQMGGRRGGRGGPGKMDKGEHRQERRDRPY 655


>gi|253970500 Ewing sarcoma breakpoint region 1 isoform 1 [Homo
           sapiens]
          Length = 661

 Score =  335 bits (860), Expect = 5e-92
 Identities = 228/553 (41%), Positives = 283/553 (51%), Gaps = 95/553 (17%)

Query: 12  GEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQSQSGYSQSYGGYE 71
           G Q +Y  YG    Q    A        + T++S  Q+ +G   Y Q   GY QS   Y 
Sbjct: 125 GTQPAYPAYGQ---QPAATAPTRPQDGNKPTETSQPQSSTG--GYNQPSLGYGQSNYSYP 179

Query: 72  NQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQQSGYDQHQGSYDE 131
            Q   SY  QP            S +Q     SYDQ  Y QQ++Y Q S Y Q Q SY +
Sbjct: 180 -QVPGSYPMQPVTAPPSYPPTSYSSTQ---PTSYDQSSYSQQNTYGQPSSYGQ-QSSYGQ 234

Query: 132 QSNYDQQHD--------SYSQNQQSYHSQRENYSHHT---QDDRRDVSRYGEDNRGYGG- 179
           QS+Y QQ          SYSQ    Y  Q  +Y   +   QD    +  YG+++ G+ G 
Sbjct: 235 QSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGP 294

Query: 180 ----SQGG----GRGRGGYDKDG--RGPMTGSSGG----DRGGFKNFGGHRDYGPRTDAD 225
               S  G    GRGRGG+D+ G  RG   G  GG    +RGGF   GG  D GP  D  
Sbjct: 295 GENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGAGERGGFNKPGGPMDEGPDLDLG 354

Query: 226 SESD---NSDNNTIFVQGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKP 282
              D   +SDN+ I+VQGL + V+ D + +FFKQ G++K NK+TG+PMI++Y DK+TGKP
Sbjct: 355 PPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKP 414

Query: 283 KGEATVSFDDPPSAKAAIDWFDGKEFHGNIIKVSFATRRPEF--MRGG------------ 328
           KG+ATVS++DPP+AKAA++WFDGK+F G+ +KVS A ++P    MRGG            
Sbjct: 415 KGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPP 474

Query: 329 --------GSGGGRRGRGGYRG--RGGFQGRG-----GDP--------KSGDWVCPNPSC 365
                   G  GG  GR G RG  RGGF  RG     G+P        ++GDW CPNP C
Sbjct: 475 LRGGPGGPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGC 534

Query: 366 GNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRSGG 425
           GN NFA R  CNQC  P+PE   P         +    G RGRGG GG RGG GG    G
Sbjct: 535 GNQNFAWRTECNQCKAPKPEGFLPP-------PFPPPGGDRGRGGPGGMRGGRGGLMDRG 587

Query: 426 GYGGDRSSGGGYSGDRSG--GGYGGDRSGGGYGGDRGGGYGGDRG------GGYGGDRGG 477
           G GG     GG  GDR G  GG G DR  GG+GG R GG GG  G      GG  G RGG
Sbjct: 588 GPGG--MFRGGRGGDRGGFRGGRGMDR--GGFGGGRRGGPGGPPGPLMEQMGGRRGGRGG 643

Query: 478 GYGGDRGGYGGDR 490
               D+G +  +R
Sbjct: 644 PGKMDKGEHRQER 656



 Score =  117 bits (293), Expect = 3e-26
 Identities = 190/707 (26%), Positives = 253/707 (35%), Gaps = 165/707 (23%)

Query: 2   SDSGSYGQSGGEQQSYSTYGNPGSQGYGQASQ-----SYSGYGQTTDSSYGQNYSGYSSY 56
           +D  +Y Q+   QQ YS Y    +QGY Q +Q     SY  YGQ TD SY Q  +  ++Y
Sbjct: 4   TDYSTYSQAAA-QQGYSAYTAQPTQGYAQTTQAYGQQSYGTYGQPTDVSYTQAQTT-ATY 61

Query: 57  GQSQSGYSQSYGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAP-SYDQPDYGQ-QD 114
           GQ+   Y+ SYG            QP   +G      S+G     AP +Y QP  G    
Sbjct: 62  GQT--AYATSYG------------QPPTVEGT-----STGYTTPTAPQAYSQPVQGYGTG 102

Query: 115 SYDQQSG-YDQHQGSYDEQSNYDQQ--HDSYSQNQQSYHSQRE---NYSHHTQDDRRDVS 168
           +YD  +      Q SY  QS Y  Q  + +Y Q   +    R    N    T   +    
Sbjct: 103 AYDTTTATVTTTQASYAAQSAYGTQPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTG 162

Query: 169 RYGEDNRGYGGSQGG-GRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDADSE 227
            Y + + GYG S     +  G Y      P+T                  Y P + + ++
Sbjct: 163 GYNQPSLGYGQSNYSYPQVPGSYPMQ---PVTAPPS--------------YPPTSYSSTQ 205

Query: 228 SDNSDNNTIFVQGL-GEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDT-----GK 281
             + D ++   Q   G+  S  Q   + +Q    +    +  P    Y+   +       
Sbjct: 206 PTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSS 265

Query: 282 PKGEATVSFDDPPSAKAAIDWFDGKEFHGNIIKVSFA------TRRPEFMRGG----GSG 331
             G+ +    D PS+        G  F G     S +        R  F RGG    G G
Sbjct: 266 SYGQQSSFRQDHPSSMGVYGQESGG-FSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRG 324

Query: 332 GGRRG-----RGGYRGRGGFQGRGGDPKSGDWVCPNPS---------------------- 364
           GGR G     RGG+   GG    G D   G  V P+                        
Sbjct: 325 GGRGGMGAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLAD 384

Query: 365 ----CGNMNFARRNSCNQCNEPRPEDSRPSGGD-----------------FRGRGYGGER 403
               CG +   +R      +    +++    GD                 F G+ + G +
Sbjct: 385 FFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSK 444

Query: 404 -----------------GYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGY 446
                            G   R GRG      GG    GG GG     GG  GDR G   
Sbjct: 445 LKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPGGPGGPMGRMGGRGGDRGGFPP 504

Query: 447 GGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGY----- 501
            G R  G  G   GGG    R G +     G  G     +  +          G+     
Sbjct: 505 RGPR--GSRGNPSGGGNVQHRAGDWQCPNPG-CGNQNFAWRTECNQCKAPKPEGFLPPPF 561

Query: 502 ---GGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGG-DRGGGSGYGGDRSGGYGGDRSGGG 557
              GGDRG     RGG GG RGG GG   RGG GG  RGG  G  G   GG G DR  GG
Sbjct: 562 PPPGGDRG-----RGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRGGFRGGRGMDR--GG 614

Query: 558 YGGDRGGGYGGDRG----GYGGKMGGR--------NDYRNDQRNRPY 592
           +GG R GG GG  G      GG+ GGR         ++R ++R+RPY
Sbjct: 615 FGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGKMDKGEHRQERRDRPY 661


>gi|4885225 Ewing sarcoma breakpoint region 1 isoform 2 [Homo
           sapiens]
          Length = 656

 Score =  335 bits (859), Expect = 7e-92
 Identities = 228/554 (41%), Positives = 283/554 (51%), Gaps = 96/554 (17%)

Query: 12  GEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQSQSGYSQSYGGYE 71
           G Q +Y  YG    Q    A        + T++S  Q+ +G   Y Q   GY QS   Y 
Sbjct: 119 GTQPAYPAYGQ---QPAATAPTRPQDGNKPTETSQPQSSTG--GYNQPSLGYGQSNYSYP 173

Query: 72  NQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQQSGYDQHQGSYDE 131
            Q   SY  QP            S +Q     SYDQ  Y QQ++Y Q S Y Q Q SY +
Sbjct: 174 -QVPGSYPMQPVTAPPSYPPTSYSSTQ---PTSYDQSSYSQQNTYGQPSSYGQ-QSSYGQ 228

Query: 132 QSNYDQQHD--------SYSQNQQSYHSQRENYSHHT---QDDRRDVSRYGEDNRGYGG- 179
           QS+Y QQ          SYSQ    Y  Q  +Y   +   QD    +  YG+++ G+ G 
Sbjct: 229 QSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGP 288

Query: 180 ----SQGG----GRGRGGYDKDG--RGPMTGSSGG-----DRGGFKNFGGHRDYGPRTDA 224
               S  G    GRGRGG+D+ G  RG   G  GG     +RGGF   GG  D GP  D 
Sbjct: 289 GENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGFNKPGGPMDEGPDLDL 348

Query: 225 DSESD---NSDNNTIFVQGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGK 281
               D   +SDN+ I+VQGL + V+ D + +FFKQ G++K NK+TG+PMI++Y DK+TGK
Sbjct: 349 GPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGK 408

Query: 282 PKGEATVSFDDPPSAKAAIDWFDGKEFHGNIIKVSFATRRPEF--MRGG----------- 328
           PKG+ATVS++DPP+AKAA++WFDGK+F G+ +KVS A ++P    MRGG           
Sbjct: 409 PKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPP 468

Query: 329 ---------GSGGGRRGRGGYRG--RGGFQGRG-----GDP--------KSGDWVCPNPS 364
                    G  GG  GR G RG  RGGF  RG     G+P        ++GDW CPNP 
Sbjct: 469 PLRGGPGGPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPG 528

Query: 365 CGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRSG 424
           CGN NFA R  CNQC  P+PE   P         +    G RGRGG GG RGG GG    
Sbjct: 529 CGNQNFAWRTECNQCKAPKPEGFLPP-------PFPPPGGDRGRGGPGGMRGGRGGLMDR 581

Query: 425 GGYGGDRSSGGGYSGDRSG--GGYGGDRSGGGYGGDRGGGYGGDRG------GGYGGDRG 476
           GG GG     GG  GDR G  GG G DR  GG+GG R GG GG  G      GG  G RG
Sbjct: 582 GGPGG--MFRGGRGGDRGGFRGGRGMDR--GGFGGGRRGGPGGPPGPLMEQMGGRRGGRG 637

Query: 477 GGYGGDRGGYGGDR 490
           G    D+G +  +R
Sbjct: 638 GPGKMDKGEHRQER 651



 Score =  114 bits (285), Expect = 3e-25
 Identities = 185/700 (26%), Positives = 250/700 (35%), Gaps = 156/700 (22%)

Query: 2   SDSGSYGQSGGEQQSYSTYGNPGSQGYGQASQ-----SYSGYGQTTDSSYGQNYSGYSSY 56
           +D  +Y Q+   QQ YS Y    +QGY Q +Q     SY  YGQ TD SY Q  +  ++Y
Sbjct: 4   TDYSTYSQAAA-QQGYSAYTAQPTQGYAQTTQAYGQQSYGTYGQPTDVSYTQAQTT-ATY 61

Query: 57  GQSQSGYSQSYGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSY 116
           GQ+   Y+ SYG    Q  + Y+  P   Q   Q ++  G+  G   +        Q SY
Sbjct: 62  GQT--AYATSYG----QPPTGYTT-PTAPQAYSQPVQGYGT--GAYDTTTATVTTTQASY 112

Query: 117 DQQSGYDQHQGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSRYGEDNRG 176
             QS Y    G+      Y QQ  + +  +     Q  N    T   +     Y + + G
Sbjct: 113 AAQSAY----GTQPAYPAYGQQPAATAPTRP----QDGNKPTETSQPQSSTGGYNQPSLG 164

Query: 177 YGGSQGG-GRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDADSESDNSDNNT 235
           YG S     +  G Y      P+T                  Y P + + ++  + D ++
Sbjct: 165 YGQSNYSYPQVPGSYPMQ---PVTAPPS--------------YPPTSYSSTQPTSYDQSS 207

Query: 236 IFVQGL-GEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDT-----GKPKGEATVS 289
              Q   G+  S  Q   + +Q    +    +  P    Y+   +         G+ +  
Sbjct: 208 YSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSF 267

Query: 290 FDDPPSAKAAIDWFDGKEFHGNIIKVSFA------TRRPEFMRGG----GSGGGRRG--- 336
             D PS+        G  F G     S +        R  F RGG    G GGGR G   
Sbjct: 268 RQDHPSSMGVYGQESGG-FSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGS 326

Query: 337 ---RGGYRGRGGFQGRGGDPKSGDWVCPNPS--------------------------CGN 367
              RGG+   GG    G D   G  V P+                            CG 
Sbjct: 327 AGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGV 386

Query: 368 MNFARRNSCNQCNEPRPEDSRPSGGD-----------------FRGRGYGGER------- 403
           +   +R      +    +++    GD                 F G+ + G +       
Sbjct: 387 VKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLAR 446

Query: 404 ----------GYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGG 453
                     G   R GRG      GG    GG GG     GG  GDR G    G R  G
Sbjct: 447 KKPPMNSMRGGLPPREGRGMPPPLRGGPGGPGGPGGPMGRMGGRGGDRGGFPPRGPR--G 504

Query: 454 GYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGY--------GGDR 505
             G   GGG    R G +     G  G     +  +          G+        GGDR
Sbjct: 505 SRGNPSGGGNVQHRAGDWQCPNPG-CGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDR 563

Query: 506 GGYGGDRGGYGGDRGGYGGDRSRGGYGG-DRGGGSGYGGDRSGGYGGDRSGGGYGGDRGG 564
           G     RGG GG RGG GG   RGG GG  RGG  G  G   GG G DR  GG+GG R G
Sbjct: 564 G-----RGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRGGFRGGRGMDR--GGFGGGRRG 616

Query: 565 GYGGDRG----GYGGKMGGR--------NDYRNDQRNRPY 592
           G GG  G      GG+ GGR         ++R ++R+RPY
Sbjct: 617 GPGGPPGPLMEQMGGRRGGRGGPGKMDKGEHRQERRDRPY 656


>gi|55956899 keratin 9 [Homo sapiens]
          Length = 623

 Score =  157 bits (396), Expect = 3e-38
 Identities = 90/171 (52%), Positives = 95/171 (55%), Gaps = 15/171 (8%)

Query: 400 GGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDR 459
           GG+  +   G      GG GG  SGG YG  R S GG     SGG YGG  SGGGYGG  
Sbjct: 460 GGQEDFESSGAGKIGLGGRGG--SGGSYG--RGSRGG-----SGGSYGGGGSGGGYGG-- 508

Query: 460 GGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGG--YGGDRGGYGGDRGGYGG 517
           G G  G  GG YGG  G G GG  GGYGG  GGG+ G  GG   GG  G YGG  G  GG
Sbjct: 509 GSGSRGGSGGSYGGGSGSG-GGSGGGYGGGSGGGHSGGSGGGHSGGSGGNYGGGSGSGGG 567

Query: 518 DRGGY-GGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDRGGGYG 567
             GGY GG  SRGG GG  GGGSG+GG+  G YGG     G GG  GGG G
Sbjct: 568 SGGGYGGGSGSRGGSGGSHGGGSGFGGESGGSYGGGEEASGSGGGYGGGSG 618



 Score =  157 bits (396), Expect = 3e-38
 Identities = 84/158 (53%), Positives = 89/158 (56%), Gaps = 4/158 (2%)

Query: 385 EDSRPSGGDFRGRG-YGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSG 443
           ED   SG    G G  GG  G  GRG RGG  G YGG  SGGGYGG   S GG  G   G
Sbjct: 463 EDFESSGAGKIGLGGRGGSGGSYGRGSRGGSGGSYGGGGSGGGYGGGSGSRGGSGGSYGG 522

Query: 444 GGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGG 503
           G   G  SGGGYGG  GGG+ G  GGG+ G  GG YGG  G  GG  GGGYGG  G  GG
Sbjct: 523 GSGSGGGSGGGYGGGSGGGHSGGSGGGHSGGSGGNYGGGSGS-GGGSGGGYGGGSGSRGG 581

Query: 504 DRGGYGGDRGGYGGDRGG-YGGDRSRGGYGGDRGGGSG 540
             G +GG   G+GG+ GG YGG     G GG  GGGSG
Sbjct: 582 SGGSHGGG-SGFGGESGGSYGGGEEASGSGGGYGGGSG 618



 Score =  106 bits (264), Expect = 7e-23
 Identities = 69/144 (47%), Positives = 75/144 (52%), Gaps = 19/144 (13%)

Query: 406 RGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDR--SGGGYGGDRS---GGGYGGDRG 460
           R  GG GG  G  G  RS   Y    SSGGG  G R  S  GYGG  S   G G GG  G
Sbjct: 13  RSGGGGGGGLGSGGSIRSS--YSRFSSSGGGGGGGRFSSSSGYGGGSSRVCGRGGGGSFG 70

Query: 461 GGYGGDRGGGYGGDR-GGGYGGDRGGYGGDRGGGY---GGDRGGYGGDRGGYGGDRGGYG 516
             YGG  GGG+     GGG+GG   G+GG  GGGY   GG  GG+GG  G  GG  GGYG
Sbjct: 71  YSYGGGSGGGFSASSLGGGFGGGSRGFGGASGGGYSSSGGFGGGFGGGSG--GGFGGGYG 128

Query: 517 GDRGGYGGDRSRGGYGGDRGGGSG 540
              GG+      GG+GG  GGG G
Sbjct: 129 SGFGGF------GGFGGGAGGGDG 146



 Score =  105 bits (263), Expect = 9e-23
 Identities = 70/142 (49%), Positives = 73/142 (51%), Gaps = 20/142 (14%)

Query: 453 GGYGGDRGGGYGGDRGGGYGGDRGGGYG-GDRGGYGGDRGGGYGGDRGGYGGDRGGYGGD 511
           GG       G G    GG GG  GG YG G RGG GG  GGG  G  GGYGG  G  GG 
Sbjct: 460 GGQEDFESSGAGKIGLGGRGGS-GGSYGRGSRGGSGGSYGGG--GSGGGYGGGSGSRGGS 516

Query: 512 RGGYGGDRGGYGGDRSRGGYGGDRGGGS------GYGGDRSGGYGGDRSGG-GYGGDRGG 564
            G YGG  G      S GG GG  GGGS      G GG  SGG GG+  GG G GG  GG
Sbjct: 517 GGSYGGGSG------SGGGSGGGYGGGSGGGHSGGSGGGHSGGSGGNYGGGSGSGGGSGG 570

Query: 565 GYG---GDRGGYGGKMGGRNDY 583
           GYG   G RGG GG  GG + +
Sbjct: 571 GYGGGSGSRGGSGGSHGGGSGF 592



 Score =  103 bits (256), Expect = 6e-22
 Identities = 62/137 (45%), Positives = 67/137 (48%), Gaps = 9/137 (6%)

Query: 422 RSGGGYGGDRSSGGGYSGD-----RSGGGYGGDR--SGGGYGGDRGGGYGGDRGGGYGGD 474
           RSGGG GG   SGG           SGGG GG R  S  GYGG      G   GG +G  
Sbjct: 13  RSGGGGGGGLGSGGSIRSSYSRFSSSGGGGGGGRFSSSSGYGGGSSRVCGRGGGGSFGYS 72

Query: 475 RGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGD 534
            GGG GG  G      GGG+GG   G+GG  GG     GG+GG  GG  G    GGYG  
Sbjct: 73  YGGGSGG--GFSASSLGGGFGGGSRGFGGASGGGYSSSGGFGGGFGGGSGGGFGGGYGSG 130

Query: 535 RGGGSGYGGDRSGGYGG 551
            GG  G+GG   GG GG
Sbjct: 131 FGGFGGFGGGAGGGDGG 147



 Score =  100 bits (250), Expect = 3e-21
 Identities = 65/140 (46%), Positives = 70/140 (50%), Gaps = 9/140 (6%)

Query: 387 SRPSGGDFRGRGYGGE-RGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGG- 444
           SR  GG   G G GG  R    R    G  GG G   S  GYGG  S   G  G  S G 
Sbjct: 12  SRSGGGGGGGLGSGGSIRSSYSRFSSSGGGGGGGRFSSSSGYGGGSSRVCGRGGGGSFGY 71

Query: 445 GYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGY---GGDRGGYGGDRGGGYGGDRGGY 501
            YGG   GG      GGG+GG    G+GG  GGGY   GG  GG+GG  GGG+G   GGY
Sbjct: 72  SYGGGSGGGFSASSLGGGFGGG-SRGFGGASGGGYSSSGGFGGGFGGGSGGGFG---GGY 127

Query: 502 GGDRGGYGGDRGGYGGDRGG 521
           G   GG+GG  GG GG  GG
Sbjct: 128 GSGFGGFGGFGGGAGGGDGG 147



 Score = 95.1 bits (235), Expect = 2e-19
 Identities = 69/173 (39%), Positives = 72/173 (41%), Gaps = 53/173 (30%)

Query: 327 GGGSGGGRRGRGGYRGRGGFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPED 386
           GGGSGGG  G  G RG  G    GG    G                              
Sbjct: 499 GGGSGGGYGGGSGSRGGSGGSYGGGSGSGGG----------------------------- 529

Query: 387 SRPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGY 446
              SGG     GYGG  G    GG  G  GG     SGG YGG   SGGG     SGGGY
Sbjct: 530 ---SGG-----GYGGGSG----GGHSGGSGGGHSGGSGGNYGGGSGSGGG-----SGGGY 572

Query: 447 GGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRG 499
           GG   G G  G  GG +GG  G G+GG+ GG YGG     G   GGGYGG  G
Sbjct: 573 GG---GSGSRGGSGGSHGG--GSGFGGESGGSYGGGEEASGS--GGGYGGGSG 618



 Score = 89.7 bits (221), Expect = 7e-18
 Identities = 67/175 (38%), Positives = 75/175 (42%), Gaps = 44/175 (25%)

Query: 326 RGGGSGGGRRGRGG--YRGRGGFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPR 383
           R GG GGG  G GG        F   GG    G +                         
Sbjct: 13  RSGGGGGGGLGSGGSIRSSYSRFSSSGGGGGGGRF------------------------- 47

Query: 384 PEDSRPSGGDFR--GRGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDR 441
              S   GG  R  GRG GG  GY   GG G   GG+     GGG+GG     GG     
Sbjct: 48  SSSSGYGGGSSRVCGRGGGGSFGYSYGGGSG---GGFSASSLGGGFGGGSRGFGG----A 100

Query: 442 SGGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGG 496
           SGGGY    S GG+    GGG+GG  GGG+GG  G G+GG  GG+GG  GGG GG
Sbjct: 101 SGGGYS---SSGGF----GGGFGGGSGGGFGGGYGSGFGG-FGGFGGGAGGGDGG 147



 Score = 89.0 bits (219), Expect = 1e-17
 Identities = 61/137 (44%), Positives = 68/137 (49%), Gaps = 13/137 (9%)

Query: 450 RSGGGYGGDRGGGYGGDRGGGYG--GDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGG 507
           RSGGG GG  G G GG     Y      GGG GG R       GGG     G  GG   G
Sbjct: 13  RSGGGGGG--GLGSGGSIRSSYSRFSSSGGGGGGGRFSSSSGYGGGSSRVCGRGGGGSFG 70

Query: 508 Y---GGDRGGYGGDR--GGYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDR 562
           Y   GG  GG+      GG+GG     G+GG  GGG    G   GG+GG  SGGG+GG  
Sbjct: 71  YSYGGGSGGGFSASSLGGGFGG--GSRGFGGASGGGYSSSGGFGGGFGGG-SGGGFGGGY 127

Query: 563 GGGYGGDRGGYGGKMGG 579
           G G+GG  GG+GG  GG
Sbjct: 128 GSGFGG-FGGFGGGAGG 143



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 44/144 (30%), Positives = 55/144 (38%), Gaps = 11/144 (7%)

Query: 81  QPYNN--QGQQQNMESSGSQ----GGRAPSYDQPDYGQQDSYDQQSGYDQHQGSYDEQS- 133
           + Y+N  +G Q++ ESSG+     GGR  S      G +       G     G Y   S 
Sbjct: 452 ETYHNLLEGGQEDFESSGAGKIGLGGRGGSGGSYGRGSRGGSGGSYGGGGSGGGYGGGSG 511

Query: 134 NYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSRYGEDNRGYGGSQGGGRGRGGYDKD 193
           +      SY     S       Y   +       S  G    G GG+ GGG G GG    
Sbjct: 512 SRGGSGGSYGGGSGSGGGSGGGYGGGSGGGHSGGSGGGHSG-GSGGNYGGGSGSGGGSGG 570

Query: 194 GRGPMTGS---SGGDRGGFKNFGG 214
           G G  +GS   SGG  GG   FGG
Sbjct: 571 GYGGGSGSRGGSGGSHGGGSGFGG 594



 Score = 40.0 bits (92), Expect = 0.006
 Identities = 32/109 (29%), Positives = 43/109 (39%), Gaps = 9/109 (8%)

Query: 5   GSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTD--------SSYGQNYSGYSSY 56
           G  G  G  + SYS + + G  G G    S SGYG  +          S+G +Y G S  
Sbjct: 20  GGLGSGGSIRSSYSRFSSSGGGGGGGRFSSSSGYGGGSSRVCGRGGGGSFGYSYGGGSGG 79

Query: 57  GQSQSGYSQSYGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSY 105
           G S S     +GG  ++     S   Y++ G        GS GG    Y
Sbjct: 80  GFSASSLGGGFGG-GSRGFGGASGGGYSSSGGFGGGFGGGSGGGFGGGY 127



 Score = 37.7 bits (86), Expect = 0.030
 Identities = 26/57 (45%), Positives = 27/57 (47%), Gaps = 6/57 (10%)

Query: 527 SRGGYGGDRGGGSGYGGDRSGGYGG-DRSGGGYGGDR---GGGYGGDRGGYGGKMGG 579
           SR G GG  GGG G GG     Y     SGGG GG R     GYGG      G+ GG
Sbjct: 12  SRSGGGG--GGGLGSGGSIRSSYSRFSSSGGGGGGGRFSSSSGYGGGSSRVCGRGGG 66



 Score = 37.7 bits (86), Expect = 0.030
 Identities = 33/102 (32%), Positives = 38/102 (37%), Gaps = 6/102 (5%)

Query: 5   GSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQSQSGYS 64
           G  G SGG     S  G+ GS G G +   Y G   +   S G    G  S G S  GY 
Sbjct: 476 GGRGGSGGSYGRGSRGGSGGSYGGGGSGGGYGGGSGSRGGSGGSYGGGSGSGGGSGGGYG 535

Query: 65  -QSYGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSY 105
             S GG+       +S     N G       SGS GG    Y
Sbjct: 536 GGSGGGHSGGSGGGHSGGSGGNYG-----GGSGSGGGSGGGY 572



 Score = 37.7 bits (86), Expect = 0.030
 Identities = 36/122 (29%), Positives = 41/122 (33%), Gaps = 9/122 (7%)

Query: 4   SGSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQSQSGY 63
           SGS G SGG     S  G     GYG  S    G G +  S  G +     +YG      
Sbjct: 510 SGSRGGSGGSYGGGSGSGGGSGGGYGGGS----GGGHSGGSGGGHSGGSGGNYGGGSGSG 565

Query: 64  SQSYGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQQSGYD 123
             S GGY     S       +  G     ES GS GG      +   G    Y   SG  
Sbjct: 566 GGSGGGYGGGSGSRGGSGGSHGGGSGFGGESGGSYGG-----GEEASGSGGGYGGGSGKS 620

Query: 124 QH 125
            H
Sbjct: 621 SH 622



 Score = 37.0 bits (84), Expect = 0.051
 Identities = 19/50 (38%), Positives = 24/50 (48%), Gaps = 5/50 (10%)

Query: 170 YGEDNRGYGGSQGGGRGR-----GGYDKDGRGPMTGSSGGDRGGFKNFGG 214
           +G  +RG+GG+ GGG        GG+     G   G  G   GGF  FGG
Sbjct: 90  FGGGSRGFGGASGGGYSSSGGFGGGFGGGSGGGFGGGYGSGFGGFGGFGG 139



 Score = 36.2 bits (82), Expect = 0.087
 Identities = 25/50 (50%), Positives = 26/50 (52%), Gaps = 8/50 (16%)

Query: 539 SGYGGDRSGGYGGDRSGGGYG----GDRGGGYGGDRGGYGGKMGGRNDYR 584
           SG G    GG GG  SGG YG    G  GG YGG  GG GG  GG +  R
Sbjct: 468 SGAGKIGLGGRGG--SGGSYGRGSRGGSGGSYGG--GGSGGGYGGGSGSR 513



 Score = 34.3 bits (77), Expect = 0.33
 Identities = 21/52 (40%), Positives = 23/52 (44%), Gaps = 6/52 (11%)

Query: 171 GEDNRGYGGSQGGGR--GRGGYDKDGRGPM----TGSSGGDRGGFKNFGGHR 216
           G    GYGG  GGG   G GG    G G      +GS GG  GG+    G R
Sbjct: 528 GGSGGGYGGGSGGGHSGGSGGGHSGGSGGNYGGGSGSGGGSGGGYGGGSGSR 579



 Score = 34.3 bits (77), Expect = 0.33
 Identities = 25/78 (32%), Positives = 29/78 (37%), Gaps = 2/78 (2%)

Query: 2   SDSGSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQT--TDSSYGQNYSGYSSYGQS 59
           S  G  G SGG     S  G     GYG  S S  G G +    S +G    G    G+ 
Sbjct: 546 SGGGHSGGSGGNYGGGSGSGGGSGGGYGGGSGSRGGSGGSHGGGSGFGGESGGSYGGGEE 605

Query: 60  QSGYSQSYGGYENQKQSS 77
            SG    YGG   +   S
Sbjct: 606 ASGSGGGYGGGSGKSSHS 623



 Score = 33.1 bits (74), Expect = 0.74
 Identities = 38/153 (24%), Positives = 55/153 (35%), Gaps = 14/153 (9%)

Query: 75  QSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQQSGYDQHQGSYDEQSN 134
           QSS  +      G Q+      SQ  +  + ++     ++ Y  Q    Q Q S  E   
Sbjct: 364 QSSAKEVTQLRHGVQELEIELQSQLSKKAALEKSLEDTKNRYCGQLQMIQEQISNLEAQI 423

Query: 135 YDQQHDSYSQNQQ---------SYHSQRENYSHHTQDDRRDVSRYGEDNRGYGGSQGGGR 185
            D + +   QNQ+             + E Y +  +  + D    G    G GG  G G 
Sbjct: 424 TDVRQEIECQNQEYSLLLSIKMRLEKEIETYHNLLEGGQEDFESSGAGKIGLGGRGGSG- 482

Query: 186 GRGGYDKDGRGPMTGS--SGGDRGGFKNFGGHR 216
             G Y +  RG   GS   GG  GG+    G R
Sbjct: 483 --GSYGRGSRGGSGGSYGGGGSGGGYGGGSGSR 513



 Score = 33.1 bits (74), Expect = 0.74
 Identities = 53/211 (25%), Positives = 63/211 (29%), Gaps = 55/211 (26%)

Query: 12  GEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQSQSGYSQSYGGYE 71
           G Q+ + + G  G  G G    S   YG+ +    G +Y G  S G         YGG  
Sbjct: 460 GGQEDFESSG-AGKIGLGGRGGSGGSYGRGSRGGSGGSYGGGGSGG--------GYGG-- 508

Query: 72  NQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQQSGYDQHQGSYDE 131
                                  SGS+GG   SY     G         GY    G    
Sbjct: 509 ----------------------GSGSRGGSGGSYGG---GSGSGGGSGGGYGGGSGG--- 540

Query: 132 QSNYDQQHDSYSQNQQSYHSQRE--NYSHHTQDDRRDVSRYGEDNR---GYGGSQGGGRG 186
                     +S      HS     NY   +         YG  +    G GGS GGG G
Sbjct: 541 ---------GHSGGSGGGHSGGSGGNYGGGSGSGGGSGGGYGGGSGSRGGSGGSHGGGSG 591

Query: 187 RGGYD--KDGRGPMTGSSGGDRGGFKNFGGH 215
            GG      G G     SGG  GG      H
Sbjct: 592 FGGESGGSYGGGEEASGSGGGYGGGSGKSSH 622



 Score = 32.7 bits (73), Expect = 0.96
 Identities = 23/68 (33%), Positives = 32/68 (47%), Gaps = 8/68 (11%)

Query: 6   SYGQSGGEQQSYSTYGNP---GSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQSQSG 62
           SYG   G   S S+ G     GS+G+G AS    G G ++   +G  + G S  G    G
Sbjct: 72  SYGGGSGGGFSASSLGGGFGGGSRGFGGAS----GGGYSSSGGFGGGFGGGSGGGFG-GG 126

Query: 63  YSQSYGGY 70
           Y   +GG+
Sbjct: 127 YGSGFGGF 134



 Score = 32.7 bits (73), Expect = 0.96
 Identities = 19/45 (42%), Positives = 22/45 (48%), Gaps = 1/45 (2%)

Query: 176 GYGGSQGGGRGRGGYDKDGRGPMTGSS-GGDRGGFKNFGGHRDYG 219
           G GGS GGG G GG    G G  +G    G  GG  + G   +YG
Sbjct: 515 GSGGSYGGGSGSGGGSGGGYGGGSGGGHSGGSGGGHSGGSGGNYG 559



 Score = 31.6 bits (70), Expect = 2.1
 Identities = 24/65 (36%), Positives = 28/65 (43%), Gaps = 1/65 (1%)

Query: 171 GEDNRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDADSESDN 230
           G    GY  S G G G GG    G G   GS  G  GGF    G  D G  T A+ +S  
Sbjct: 99  GASGGGYSSSGGFGGGFGGGSGGGFGGGYGSGFGGFGGFGGGAGGGDGGILT-ANEKSTM 157

Query: 231 SDNNT 235
            + N+
Sbjct: 158 QELNS 162



 Score = 29.6 bits (65), Expect = 8.2
 Identities = 16/42 (38%), Positives = 18/42 (42%), Gaps = 2/42 (4%)

Query: 178 GGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYG 219
           GG  GGG G GG  +      + S GG  GG   F     YG
Sbjct: 15  GGGGGGGLGSGGSIRSSYSRFSSSGGGGGGG--RFSSSSGYG 54


>gi|14043070 heterogeneous nuclear ribonucleoprotein A1 isoform b
           [Homo sapiens]
          Length = 372

 Score =  147 bits (371), Expect = 3e-35
 Identities = 121/346 (34%), Positives = 153/346 (44%), Gaps = 71/346 (20%)

Query: 221 RTDADSESDNSDNNTIFVQGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTG 280
           R D+     +     IFV G+ E      + ++F+Q G I+        +I + TD+ +G
Sbjct: 92  REDSQRPGAHLTVKKIFVGGIKEDTEEHHLRDYFEQYGKIE--------VIEIMTDRGSG 143

Query: 281 KPKGEATVSFDDPPSAKAAIDWFDGKEFH---GNIIKVSFATRRPEFMRGGGSGGGRRGR 337
           K +G A V+FDD  S    +D    +++H   G+  +V  A  + E      S  GR G 
Sbjct: 144 KKRGFAFVTFDDHDS----VDKIVIQKYHTVNGHNCEVRKALSKQEMASASSSQRGRSGS 199

Query: 338 GGYRGRGGFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGR 397
           G + G     GRGG              GN NF R                  GG+F GR
Sbjct: 200 GNFGG-----GRGGG-----------FGGNDNFGR------------------GGNFSGR 225

Query: 398 GYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGG 457
             GG  G RG GG GG   GY G  + GGYGG    G GYSG   G G GG     GY G
Sbjct: 226 --GGFGGSRGGGGYGGSGDGYNGFGNDGGYGG---GGPGYSGGSRGYGSGGQ----GY-G 275

Query: 458 DRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGG 517
           ++G GYGG   G Y     GG     GG+GG  G  +GG  GG   D G Y      +G 
Sbjct: 276 NQGSGYGG--SGSYDSYNNGG----GGGFGGGSGSNFGG--GGSYNDFGNYNNQSSNFGP 327

Query: 518 DRGGYGGDRSRGGYGGDRGGGSGYGGDRS-GGYGGDRSGGGYGGDR 562
            +GG  G RS G YG   GGG  +   R+ GGYGG  S   YG  R
Sbjct: 328 MKGGNFGGRSSGPYG---GGGQYFAKPRNQGGYGGSSSSSSYGSGR 370



 Score =  124 bits (311), Expect = 2e-28
 Identities = 81/178 (45%), Positives = 93/178 (52%), Gaps = 15/178 (8%)

Query: 402 ERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGG-DRG 460
           +RG  G G  GG RGG  G     G GG+ S  GG+ G R GGGYGG  SG GY G    
Sbjct: 193 QRGRSGSGNFGGGRGGGFGGNDNFGRGGNFSGRGGFGGSRGGGGYGG--SGDGYNGFGND 250

Query: 461 GGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRG 520
           GGYGG   G  GG RG G GG   GY G++G GYGG  G Y     G GG  G  GG   
Sbjct: 251 GGYGGGGPGYSGGSRGYGSGGQ--GY-GNQGSGYGGS-GSYDSYNNGGGGGFG--GGSGS 304

Query: 521 GYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDRGGGYGG---DRGGYGG 575
            +GG  S   +G      S +G  + G +GG RS G YGG  GG Y     ++GGYGG
Sbjct: 305 NFGGGGSYNDFGNYNNQSSNFGPMKGGNFGG-RSSGPYGG--GGQYFAKPRNQGGYGG 359



 Score =  107 bits (267), Expect = 3e-23
 Identities = 65/140 (46%), Positives = 75/140 (53%), Gaps = 22/140 (15%)

Query: 450 RSGGG-YGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGG-YGGDRGGYGG--DR 505
           RSG G +GG RGGG+GG+   G    RGG + G RGG+GG RGGG YGG   GY G  + 
Sbjct: 196 RSGSGNFGGGRGGGFGGNDNFG----RGGNFSG-RGGFGGSRGGGGYGGSGDGYNGFGND 250

Query: 506 GGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDRGGG 565
           GGYGG   GY G   GYG             GG GY G++  GYGG  S   Y    GGG
Sbjct: 251 GGYGGGGPGYSGGSRGYG------------SGGQGY-GNQGSGYGGSGSYDSYNNGGGGG 297

Query: 566 YGGDRGGYGGKMGGRNDYRN 585
           +GG  G   G  G  ND+ N
Sbjct: 298 FGGGSGSNFGGGGSYNDFGN 317



 Score = 55.5 bits (132), Expect = 1e-07
 Identities = 31/64 (48%), Positives = 38/64 (59%), Gaps = 9/64 (14%)

Query: 524 GDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSG-GGYGGDRGGGYGGDRGGYGGKMGGRND 582
           G    G +GG RGGG  +GG+ + G GG+ SG GG+GG RGGG      GYGG   G N 
Sbjct: 195 GRSGSGNFGGGRGGG--FGGNDNFGRGGNFSGRGGFGGSRGGG------GYGGSGDGYNG 246

Query: 583 YRND 586
           + ND
Sbjct: 247 FGND 250



 Score = 49.7 bits (117), Expect = 8e-06
 Identities = 36/115 (31%), Positives = 49/115 (42%), Gaps = 7/115 (6%)

Query: 6   SYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQSQSGYSQ 65
           ++G+ G         G+ G  GYG +   Y+G+G   D  YG    GYS   +      Q
Sbjct: 215 NFGRGGNFSGRGGFGGSRGGGGYGGSGDGYNGFGN--DGGYGGGGPGYSGGSRGYGSGGQ 272

Query: 66  SYGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQQS 120
            YG   +    S S   YNN G       SGS  G   SY+  D+G   +Y+ QS
Sbjct: 273 GYGNQGSGYGGSGSYDSYNNGGGGGFGGGSGSNFGGGGSYN--DFG---NYNNQS 322



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 37/152 (24%), Positives = 55/152 (36%), Gaps = 14/152 (9%)

Query: 71  ENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPD-YGQQDSYDQQSGYDQHQGSY 129
           E +K  S  +    +  Q+    S    GGR   +   D +G+  ++  + G+   +G  
Sbjct: 176 EVRKALSKQEMASASSSQRGRSGSGNFGGGRGGGFGGNDNFGRGGNFSGRGGFGGSRGG- 234

Query: 130 DEQSNYDQQHDSYSQ--NQQSYHSQRENYSHHTQDDRRDVSRYGEDNRGYGGSQGGGRGR 187
                Y    D Y+   N   Y      YS  ++        YG   +GYG    G  G 
Sbjct: 235 ---GGYGGSGDGYNGFGNDGGYGGGGPGYSGGSRG-------YGSGGQGYGNQGSGYGGS 284

Query: 188 GGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYG 219
           G YD    G   G  GG    F   G + D+G
Sbjct: 285 GSYDSYNNGGGGGFGGGSGSNFGGGGSYNDFG 316



 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 41/137 (29%), Positives = 55/137 (40%), Gaps = 16/137 (11%)

Query: 5   GSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSG----YGQTTDSSYGQNYSGYSSYGQSQ 60
           G YG SG     Y+ +GN G  GYG     YSG    YG +    YG   SGY   G   
Sbjct: 235 GGYGGSG---DGYNGFGNDG--GYGGGGPGYSGGSRGYG-SGGQGYGNQGSGYGGSGSYD 288

Query: 61  SGYSQSYGGYENQKQSSY-SQQPYNNQGQQQNMESS--GSQGGRAPSYDQPDYGQQDSYD 117
           S  +   GG+     S++     YN+ G   N  S+    +GG         YG    Y 
Sbjct: 289 SYNNGGGGGFGGGSGSNFGGGGSYNDFGNYNNQSSNFGPMKGGNFGGRSSGPYGGGGQYF 348

Query: 118 QQSGYDQHQGSYDEQSN 134
            +    ++QG Y   S+
Sbjct: 349 AK---PRNQGGYGGSSS 362



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 50/207 (24%), Positives = 68/207 (32%), Gaps = 32/207 (15%)

Query: 16  SYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQSQSGYSQSYGGYENQKQ 75
           S S  G  GS  +G       G+G   +   G N+SG   +G S+ G    YGG      
Sbjct: 190 SSSQRGRSGSGNFGGGRGG--GFGGNDNFGRGGNFSGRGGFGGSRGG--GGYGG------ 239

Query: 76  SSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQQSGYDQHQGSYDEQSNY 135
              S   YN  G      + G  GG  P Y     G +       GY      Y    +Y
Sbjct: 240 ---SGDGYNGFG------NDGGYGGGGPGYSG---GSRGYGSGGQGYGNQGSGYGGSGSY 287

Query: 136 DQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSRYGEDNRGYGGSQG---GGRGRGGYDK 192
               DSY+             +        D   Y   +  +G  +G   GGR  G Y  
Sbjct: 288 ----DSYNNGGGGGFGGGSGSNFGGGGSYNDFGNYNNQSSNFGPMKGGNFGGRSSGPY-- 341

Query: 193 DGRGPMTGSSGGDRGGFKNFGGHRDYG 219
            G G    +   ++GG+        YG
Sbjct: 342 -GGGGQYFAKPRNQGGYGGSSSSSSYG 367



 Score = 40.0 bits (92), Expect = 0.006
 Identities = 30/107 (28%), Positives = 40/107 (37%), Gaps = 14/107 (13%)

Query: 5   GSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQSQSGYS 64
           G+ G   G   SY +Y N G  G+G  S S  G         G +Y+ + +Y    S + 
Sbjct: 275 GNQGSGYGGSGSYDSYNNGGGGGFGGGSGSNFG--------GGGSYNDFGNYNNQSSNFG 326

Query: 65  QSYGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYG 111
              GG    + S     PY   GQ        +QGG   S     YG
Sbjct: 327 PMKGGNFGGRSSG----PYGGGGQY--FAKPRNQGGYGGSSSSSSYG 367



 Score = 38.5 bits (88), Expect = 0.018
 Identities = 28/76 (36%), Positives = 31/76 (40%), Gaps = 3/76 (3%)

Query: 171 GEDNRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDADSESDN 230
           G DN G GG+     GRGG+     G   G SG    GF N GG+   GP     S    
Sbjct: 212 GNDNFGRGGNF---SGRGGFGGSRGGGGYGGSGDGYNGFGNDGGYGGGGPGYSGGSRGYG 268

Query: 231 SDNNTIFVQGLGEGVS 246
           S       QG G G S
Sbjct: 269 SGGQGYGNQGSGYGGS 284



 Score = 32.3 bits (72), Expect = 1.3
 Identities = 21/62 (33%), Positives = 27/62 (43%), Gaps = 2/62 (3%)

Query: 174 NRGYGGSQGGGRGRGGYDKDGR--GPMTGSSGGDRGGFKNFGGHRDYGPRTDADSESDNS 231
           +RG GG  G G G  G+  DG   G   G SGG RG      G+ + G         D+ 
Sbjct: 231 SRGGGGYGGSGDGYNGFGNDGGYGGGGPGYSGGSRGYGSGGQGYGNQGSGYGGSGSYDSY 290

Query: 232 DN 233
           +N
Sbjct: 291 NN 292


>gi|34740329 heterogeneous nuclear ribonucleoprotein A3 [Homo
           sapiens]
          Length = 378

 Score =  144 bits (364), Expect = 2e-34
 Identities = 122/323 (37%), Positives = 153/323 (47%), Gaps = 78/323 (24%)

Query: 236 IFVQGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATVSFDDPPS 295
           IFV G+ E      + ++F++ G I+T        I +  D+ +GK +G A V+FDD  +
Sbjct: 128 IFVGGIKEDTEEYNLRDYFEKYGKIET--------IEVMEDRQSGKKRGFAFVTFDDHDT 179

Query: 296 AKAAIDWFDGKEFH---GNIIKVSFATRRPEFMRGGGSGGGRRGRGGYRGRGGFQGRGGD 352
               +D    +++H   G+  +V  A  + E      S G +RGRGG  G G F GRGG 
Sbjct: 180 ----VDKIVVQKYHTINGHNCEVKKALSKQEMQ----SAGSQRGRGG--GSGNFMGRGG- 228

Query: 353 PKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGRGGRG 412
                    N   G  NF R                  GG+F GRG  G  G   RG  G
Sbjct: 229 ---------NFGGGGGNFGR------------------GGNFGGRGGYGGGGGGSRGSYG 261

Query: 413 GDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRGGGYG 472
           G  GGY       G+GGD  + GG  G  S GGYGG   G GY G++GGGYGG  GGGY 
Sbjct: 262 GGDGGY------NGFGGDGGNYGGGPGYSSRGGYGG--GGPGY-GNQGGGYGG--GGGYD 310

Query: 473 G-DRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGG- 530
           G + GG +GG  G YGG  GG Y  D G Y G +      +  YG  +GG  G RS G  
Sbjct: 311 GYNEGGNFGG--GNYGG--GGNY-NDFGNYSGQQ------QSNYGPMKGGSFGGRSSGSP 359

Query: 531 YGGDRGGGSGYGGDRSGGYGGDR 553
           YGG  G G G     SGGYG  R
Sbjct: 360 YGGGYGSGGG-----SGGYGSRR 377



 Score =  128 bits (322), Expect = 1e-29
 Identities = 92/191 (48%), Positives = 101/191 (52%), Gaps = 27/191 (14%)

Query: 390 SGGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGD 449
           S G  RGRG GG   + GRGG  G  GG  G   GG +GG     GGY     GGG GG 
Sbjct: 209 SAGSQRGRG-GGSGNFMGRGGNFGGGGGNFG--RGGNFGGR----GGY-----GGGGGGS 256

Query: 450 RSGGGYGGDRGG--GYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGG 507
           R  G YGG  GG  G+GGD  G YGG  G GY   RGGYGG  G GYG   GGYGG  G 
Sbjct: 257 R--GSYGGGDGGYNGFGGDG-GNYGG--GPGY-SSRGGYGGG-GPGYGNQGGGYGGGGGY 309

Query: 508 YGGDRGGY--GGDRGGYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDRGGG 565
            G + GG   GG+ GG G     G Y G +   S YG  + G +GG  SG  YGG  G G
Sbjct: 310 DGYNEGGNFGGGNYGGGGNYNDFGNYSGQQ--QSNYGPMKGGSFGGRSSGSPYGG--GYG 365

Query: 566 YGGDRGGYGGK 576
            GG  GGYG +
Sbjct: 366 SGGGSGGYGSR 376



 Score =  119 bits (298), Expect = 8e-27
 Identities = 76/160 (47%), Positives = 86/160 (53%), Gaps = 21/160 (13%)

Query: 428 GGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYG 487
           G  R  GGG SG+  G G  G+  GGG    RGG +GG   GGYGG    G GG RG YG
Sbjct: 211 GSQRGRGGG-SGNFMGRG--GNFGGGGGNFGRGGNFGGR--GGYGG----GGGGSRGSYG 261

Query: 488 GDRGG--GYGGDRGGYGG-----DRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSG 540
           G  GG  G+GGD G YGG      RGGYGG   GYG   GGYGG    GGY G   GG+ 
Sbjct: 262 GGDGGYNGFGGDGGNYGGGPGYSSRGGYGGGGPGYGNQGGGYGGG---GGYDGYNEGGN- 317

Query: 541 YGGDRSGGYGGDRSGGGYGGDRGGGYGGDRGG-YGGKMGG 579
           +GG   GG G     G Y G +   YG  +GG +GG+  G
Sbjct: 318 FGGGNYGGGGNYNDFGNYSGQQQSNYGPMKGGSFGGRSSG 357



 Score =  117 bits (292), Expect = 4e-26
 Identities = 77/146 (52%), Positives = 87/146 (59%), Gaps = 20/146 (13%)

Query: 441 RSGGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGG 500
           +S G   G   G G    RGG +GG  GG +G  RGG +GG RGGYGG    G GG RG 
Sbjct: 208 QSAGSQRGRGGGSGNFMGRGGNFGGG-GGNFG--RGGNFGG-RGGYGG----GGGGSRGS 259

Query: 501 YGGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGG 560
           YGG  GGY G  GG GG+ GG  G  SRGGYG   GGG GY G++ GGYGG   GGGY G
Sbjct: 260 YGGGDGGYNGF-GGDGGNYGGGPGYSSRGGYG---GGGPGY-GNQGGGYGG---GGGYDG 311

Query: 561 -DRGGGYGGDRGGYGGKMGGRNDYRN 585
            + GG +GG  G YGG  G  ND+ N
Sbjct: 312 YNEGGNFGG--GNYGGG-GNYNDFGN 334



 Score = 85.5 bits (210), Expect = 1e-16
 Identities = 59/114 (51%), Positives = 63/114 (55%), Gaps = 12/114 (10%)

Query: 481 GDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGY--GGDRSRGGYGGDRGGG 538
           G + G GG  G   G  RGG  G  GG  G RGG  G RGGY  GG  SRG YGG  GG 
Sbjct: 211 GSQRGRGGGSGNFMG--RGGNFGGGGGNFG-RGGNFGGRGGYGGGGGGSRGSYGGGDGGY 267

Query: 539 SGYGGDRSGGYGGD---RSGGGYGGDRGGGYGGDRGGYGGKMGGRNDYRNDQRN 589
           +G+GGD  G YGG     S GGYGG  G GYG   GGYGG  GG  D  N+  N
Sbjct: 268 NGFGGD-GGNYGGGPGYSSRGGYGGG-GPGYGNQGGGYGG--GGGYDGYNEGGN 317



 Score = 50.4 bits (119), Expect = 4e-06
 Identities = 56/195 (28%), Positives = 73/195 (37%), Gaps = 50/195 (25%)

Query: 1   MSDSGSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQSQ 60
           M   G++G  GG   ++   GN G +G       Y G G  +  SYG    GY+ +G   
Sbjct: 224 MGRGGNFGGGGG---NFGRGGNFGGRG------GYGGGGGGSRGSYGGGDGGYNGFG--- 271

Query: 61  SGYSQSYGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQP--DYGQQDSYD- 117
            G   +YGG        YS              S G  GG  P Y      YG    YD 
Sbjct: 272 -GDGGNYGG-----GPGYS--------------SRGGYGGGGPGYGNQGGGYGGGGGYDG 311

Query: 118 QQSGYDQHQGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSRYGEDNRG- 176
              G +   G+Y    NY+    +YS  QQS +   +  S            +G  + G 
Sbjct: 312 YNEGGNFGGGNYGGGGNYN-DFGNYSGQQQSNYGPMKGGS------------FGGRSSGS 358

Query: 177 -YGGSQGGGRGRGGY 190
            YGG  G G G GGY
Sbjct: 359 PYGGGYGSGGGSGGY 373



 Score = 39.7 bits (91), Expect = 0.008
 Identities = 40/145 (27%), Positives = 54/145 (37%), Gaps = 16/145 (11%)

Query: 89  QQNMESSGSQGGRAPSYDQPDYGQQDSYDQQSGYDQHQGSYDEQSNYDQ----QHDSYSQ 144
           +Q M+S+GSQ GR         G+  ++    G     G++  +  Y         SY  
Sbjct: 204 KQEMQSAGSQRGRGGGSGN-FMGRGGNFGGGGGNFGRGGNFGGRGGYGGGGGGSRGSYGG 262

Query: 145 NQQSYHS---QRENYSHHTQDDRRDVSRYGEDNRGYGGSQGGGRGRGGYDKDGRGPMTG- 200
               Y+       NY        R    YG    GYG   GG  G GGYD    G   G 
Sbjct: 263 GDGGYNGFGGDGGNYGGGPGYSSR--GGYGGGGPGYGNQGGGYGGGGGYDGYNEGGNFGG 320

Query: 201 ---SSGGDRGGFKNFGGHR--DYGP 220
                GG+   F N+ G +  +YGP
Sbjct: 321 GNYGGGGNYNDFGNYSGQQQSNYGP 345



 Score = 36.2 bits (82), Expect = 0.087
 Identities = 31/123 (25%), Positives = 54/123 (43%), Gaps = 17/123 (13%)

Query: 106 DQPDYGQQDSYDQQSGYDQHQGSYDEQSNYDQ--------QHDSYSQNQ-QSYHSQRENY 156
           D  +Y  +D +++    +  +   D QS   +         HD+  +   Q YH+     
Sbjct: 136 DTEEYNLRDYFEKYGKIETIEVMEDRQSGKKRGFAFVTFDDHDTVDKIVVQKYHT----I 191

Query: 157 SHHTQDDRRDVSRYGEDNRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHR 216
           + H  + ++ +S+  ++ +  G  +G G G G +   GRG   G  GG+ G   NFGG  
Sbjct: 192 NGHNCEVKKALSK--QEMQSAGSQRGRGGGSGNFM--GRGGNFGGGGGNFGRGGNFGGRG 247

Query: 217 DYG 219
            YG
Sbjct: 248 GYG 250



 Score = 32.0 bits (71), Expect = 1.6
 Identities = 26/65 (40%), Positives = 30/65 (46%), Gaps = 5/65 (7%)

Query: 171 GEDNRG-YGGSQGGGRGRGGYDKD-GRGPMTGSSGGDRGG---FKNFGGHRDYGPRTDAD 225
           G  +RG YGG  GG  G GG   + G GP   S GG  GG   + N GG    G   D  
Sbjct: 253 GGGSRGSYGGGDGGYNGFGGDGGNYGGGPGYSSRGGYGGGGPGYGNQGGGYGGGGGYDGY 312

Query: 226 SESDN 230
           +E  N
Sbjct: 313 NEGGN 317



 Score = 30.0 bits (66), Expect = 6.2
 Identities = 18/42 (42%), Positives = 20/42 (47%), Gaps = 4/42 (9%)

Query: 180 SQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPR 221
           S G  RGRGG    G G   G  G   GG  NFG   ++G R
Sbjct: 209 SAGSQRGRGG----GSGNFMGRGGNFGGGGGNFGRGGNFGGR 246


>gi|57864582 hornerin [Homo sapiens]
          Length = 2850

 Score =  133 bits (334), Expect = 5e-31
 Identities = 159/602 (26%), Positives = 208/602 (34%), Gaps = 73/602 (12%)

Query: 4    SGSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSS---YGQSQ 60
            S  YGQ G      ST+G  GS     +S    G      SS+GQ+ SG S    YG+  
Sbjct: 1530 SSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQG 1589

Query: 61   SGYSQSYGGYENQKQSSYSQQP-YNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQQ 119
            SG  QS G    Q+ S   Q P Y   G      SS  Q G            + S  Q 
Sbjct: 1590 SGSGQSPG--HGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQS 1647

Query: 120  SGYDQHQGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSRYGEDNRGYGG 179
            S Y QH       S Y Q     S++ QS   +R   S       R  SRYG+   G G 
Sbjct: 1648 SSYSQHGSGSGHSSGYGQHG---SRSGQSSRGERHGSSS------RSSSRYGQ--HGSGS 1696

Query: 180  SQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDADSESDN-SDNNTIFV 238
             Q  G GR G    G+ P  G  G   G   + G H     R+ +    ++ S ++++F 
Sbjct: 1697 RQSSGHGRQG-SGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVF- 1754

Query: 239  QGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATVSFDDPPSAKA 298
                        G+     G      + G    +  +    G   G+++ +FD   S+  
Sbjct: 1755 ------------GQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSS-TFDQEGSSTG 1801

Query: 299  AIDWFDGKEFHGNIIKVSFATRRPEFMRGGGSGG----GRRGRG-GYRGRGGFQGRGGDP 353
                  G+   G+    S+        +G GSG     GR G G G+    G  G G   
Sbjct: 1802 QSS-SHGQHGSGSSQSSSYG------QQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGW 1854

Query: 354  KSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGRGGRGG 413
             S      + S  +  F    S +  +    +    SG       +G   G   RG + G
Sbjct: 1855 SSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHG 1914

Query: 414  DRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRGGGYGG 473
               G        G G  +S G G  G  SG      R   G G  +   Y     G YG 
Sbjct: 1915 SSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSY-----GPYGS 1969

Query: 474  DRGGGYGGDRGGYGGDRGGGYG-GDRGGYGGDRGGYG--GDRGGYGGDRGGYGGDRSRGG 530
              G G+   RG Y    G   G G R    G   GYG  G   G+    G +G    +  
Sbjct: 1970 --GSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSASGQSS 2027

Query: 531  YGGDRGGGSGY---------GGDRSGGYGGDRSGGGYG---GDRGGG------YGGDRGG 572
              G  G  SG          G  +S GYG   SG G     G RG G      YG    G
Sbjct: 2028 SCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSG 2087

Query: 573  YG 574
             G
Sbjct: 2088 SG 2089



 Score =  128 bits (321), Expect = 2e-29
 Identities = 170/613 (27%), Positives = 218/613 (35%), Gaps = 95/613 (15%)

Query: 4    SGSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQSQSGY 63
            S  YGQ G      ST+G  GS     AS   S  GQ   SS GQ+    SS+GQ  SG 
Sbjct: 2000 SSGYGQHGSSSGHSSTHGQHGS-----ASGQSSSCGQHGASS-GQS----SSHGQHGSGS 2049

Query: 64   SQSYGGYENQKQSSYSQQPYNNQGQQQNMESS----GSQGGRAPSYDQPDYGQQDSYDQQ 119
            SQS  GY  Q   S     +  +G       S    GS  GR+ S  Q   G  +S    
Sbjct: 2050 SQS-SGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLGES---- 2104

Query: 120  SGYDQHQGSYDEQSNYDQQHDSYSQNQQSY--HSQRENYSHHTQ---DDRRDVSRYGEDN 174
            SG+  H+ S  + S+Y  QH S S +   Y  H  R   S   +         SRYG+  
Sbjct: 2105 SGFGHHESSSGQSSSY-SQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSRYGQ-- 2161

Query: 175  RGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDADSESDN-SDN 233
             G G  Q  G GR G    G  P  G  G   G   + G H     R+ +    ++ S +
Sbjct: 2162 HGSGSRQSSGHGRQG-SGSGHSPSRGRHGSGSGHSSSHGQHGSGSGRSSSRGPYESRSGH 2220

Query: 234  NTIFVQGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATVSFDDP 293
            +++F             G+     G      + G    +  +    G   G+++ +FD  
Sbjct: 2221 SSVF-------------GQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSS-TFDQE 2266

Query: 294  PSAKAAIDWFDGKEFHGNIIKVSFATRRPEFMRGGGSG----GGRRGRG-GYRGRGGFQG 348
             S+        G+   G+    S+        +G GSG     GR G G G+    G  G
Sbjct: 2267 GSSTGQSS-SHGQHGSGSSQSSSYG------QQGSGSGQSPSRGRHGSGSGHSSSYGQHG 2319

Query: 349  RGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGR 408
             G    S      + S  +  F    S +          + SG    G G G    Y   
Sbjct: 2320 SGSGWSSSSGRHGSGSGQSSGFGHHESSSW---------QSSGYTQHGSGSGHSSSYEQH 2370

Query: 409  GGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYG-----GDRGGGY 463
            G R G      G+R G   G   S G   SG R   G+G   SG G       G  G G 
Sbjct: 2371 GSRSGQSS--RGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGS 2428

Query: 464  GGDRG-GGYGGDRGGGYGGDRGGYGGDRGGGYG-GDRGGYGGDRGGYG--GDRGGYGGDR 519
            G       YG   G G+   RG Y    G   G G R    G   GYG  G   G+    
Sbjct: 2429 GQSSSYSPYGS--GSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTH 2486

Query: 520  GGYGGDRSRGGYGGDRGGGSGY---------GGDRSGGYGGDRSGGGYG---GDRGGG-- 565
            G +G    +    G  G  SG          G  +S GYG   SG G     G RG G  
Sbjct: 2487 GQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSR 2546

Query: 566  ----YGGDRGGYG 574
                YG    G G
Sbjct: 2547 QSPSYGRHGSGSG 2559



 Score =  126 bits (317), Expect = 5e-29
 Identities = 166/608 (27%), Positives = 207/608 (34%), Gaps = 85/608 (13%)

Query: 4    SGSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSG---YSSYGQSQ 60
            S  YGQ G      ST+G  GS     +S    G      SS+GQ+ SG    S YG+  
Sbjct: 1060 SSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQG 1119

Query: 61   SGYSQSYGGYENQKQSSYSQQP-YNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQQ 119
            SG  QS G    Q+ S   Q P Y   G      SS  Q G            + S  Q 
Sbjct: 1120 SGSGQSPG--HGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQS 1177

Query: 120  SGYDQHQGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSRYGEDNRGYGG 179
            S Y QH       S Y Q     S++ QS   +R   S  +       S YG+   G G 
Sbjct: 1178 SSYSQHGSGSGHSSGYGQHG---SRSGQSSRGERHGSSSGSS------SHYGQ--HGSGS 1226

Query: 180  SQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDADSESDN-SDNNTIFV 238
             Q  G GR G    G  P  G  G   G   + G H     R+ +    ++ S ++++F 
Sbjct: 1227 RQSSGHGRQG-SGSGHSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFG 1285

Query: 239  Q---GLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATVSFDDPPS 295
            Q   G G   +  Q G      G   +  + G       T    G   G+++ S+    S
Sbjct: 1286 QHESGSGHSSAYSQHG---SGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSS-SYGHRGS 1341

Query: 296  AKAAIDWFDGKEFHGNIIKVSFATRRPEFMRGGGSGGGRRGRG-GYRGRGGFQGRGGDPK 354
              +      G   HG     S +  R     G  S  G+ G G G+    G  G G    
Sbjct: 1342 GSSQ---SSGYGRHGAGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQS 1398

Query: 355  SGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGRGGRGGD 414
            SG             F    S +          + SG    G G G    Y   G R G 
Sbjct: 1399 SG-------------FGHHESSSW---------QSSGCTQHGSGSGHSSSYEQHGSRSGQ 1436

Query: 415  RGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYG-----GDRGGGYGGDRG- 468
                 G+R G   G   S G   SG R   G+G   SG G       G  G G G     
Sbjct: 1437 SS--RGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSY 1494

Query: 469  GGYGGDRGGGYGGDRGGY--GGDRGGGYGGDRGGYGGDRGGYG--GDRGGYGGDRGGYGG 524
              YG   G G+   RG Y  G     G  G R    G   GYG  G   G+    G +G 
Sbjct: 1495 SPYGS--GSGWSSSRGPYESGSSHSSGL-GHRESRSGQSSGYGQHGSSSGHSSTHGQHGS 1551

Query: 525  DRSRGGYGGDRGGGSGY---------GGDRSGGYGGDRSGGGYG---GDRGGG------Y 566
               +    G  G  SG          G  +S GYG   SG G     G RG G      Y
Sbjct: 1552 TSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSY 1611

Query: 567  GGDRGGYG 574
            G    G G
Sbjct: 1612 GRHGSGSG 1619



 Score =  124 bits (312), Expect = 2e-28
 Identities = 163/611 (26%), Positives = 209/611 (34%), Gaps = 63/611 (10%)

Query: 4    SGSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGY---SSYGQ-- 58
            S S+GQ G      S YG  GS      S+   G      SSYGQ+ SG    SS G   
Sbjct: 633  SSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSSSNGPHG 692

Query: 59   SQSGYSQSYGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQ--------PDY 110
            S SG S  +G      QSS   Q  +           GS+ G++   +Q          Y
Sbjct: 693  SVSGQSSGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSY 752

Query: 111  GQQDSYDQQSGYDQHQGSYDEQSNYDQQHDSYSQNQQSYHSQRENYS-----HHTQDDRR 165
            GQ  S   QS     QGS    S    +H S S +  S+       S      H +    
Sbjct: 753  GQHGSGSHQSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQHGSGTSCSSSCGHYESGSG 812

Query: 166  DVSRYGEDNRGYG-GSQGGGRGRGGYDKDGR-GPMTGSSGGDRGGFKNFGGHRDYGPRTD 223
              S +G+   G G G    G   G +   GR G  +G S        + G    YG    
Sbjct: 813  QASGFGQHESGSGQGYSQHGSASGHFSSQGRHGSTSGQSSSSGQHDSSSGQSSSYGQH-- 870

Query: 224  ADSESDNSDNNTIFVQGLGEGVSTDQVGEFFKQIGII-KTNKKTGKPMINLYTDKDTGKP 282
             +S S ++        G G+     Q G    Q     +    +G+   +      +G+ 
Sbjct: 871  -ESASHHASGRGRHGSGSGQSPGHGQRGSGSGQSPSYGRHGSGSGRSSSSGRHGSGSGQS 929

Query: 283  KGEATVSFDDPPSAKAAIDWFDGK----EFHGNIIKVSFATRRPEFMRGGGSGGGRRGRG 338
             G    S     S         G     E HG+    S  + +     G  S  G+ G G
Sbjct: 930  SGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRSEQHGSSSGSSSSYGQHGSG 989

Query: 339  GYRGRGGFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRG-- 396
              +  G  Q   G  +S     P+PS G       +   Q +   P  S       RG  
Sbjct: 990  SRQSLGHGQHGSGSGQS-----PSPSRGRHG----SGSGQSSSYGPYRSGSGWSSSRGPY 1040

Query: 397  -RGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSG--- 452
              G G   G   R  R G   GYG   S  G+       G  SG  S  G  G  SG   
Sbjct: 1041 ESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSS 1100

Query: 453  ----GGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGY 508
                 G G  +  GY G +G G G   G G    + G G  +   YG  R G G  R   
Sbjct: 1101 SHGQHGSGSSQSSGY-GRQGSGSGQSPGHG----QRGSGSRQSPSYG--RHGSGSGRSSS 1153

Query: 509  GGDRGGYGGDRGGYGGDRSRGGYG---GDRGGGSGYGGDRSGGYG--GDRSGGGYGGDRG 563
             G  G   G+  G+G   S  G        G GSG+    S GYG  G RSG    G+R 
Sbjct: 1154 SGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGH----SSGYGQHGSRSGQSSRGERH 1209

Query: 564  GGYGGDRGGYG 574
            G   G    YG
Sbjct: 1210 GSSSGSSSHYG 1220



 Score =  124 bits (310), Expect = 3e-28
 Identities = 158/591 (26%), Positives = 214/591 (36%), Gaps = 46/591 (7%)

Query: 4   SGSYGQSGGEQQSYSTYGNPGSQGYGQA---SQSYSGYGQTTDSSYGQNYSGYSS-YGQS 59
           S SYG+   +    S  G  GS G GQ+    Q  SG GQ++ +    + SG SS + Q 
Sbjct: 176 SSSYGEQNSDSHQSSGRGQCGS-GSGQSPNYGQHGSGSGQSSSNDTHGSGSGQSSGFSQH 234

Query: 60  QSGYSQSYGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQQ 119
           +S   QS  GY      S     Y   G +    S G +  R+ S     YGQ  S  +Q
Sbjct: 235 KSSSGQS-SGYSQHGSGSGHSSGYGQHGSRSGQSSRGER-HRSSSGSSSSYGQHGSGSRQ 292

Query: 120 SGYDQHQGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSRYGEDNRGYGG 179
           S     QGS   QS    +H S S +  S H Q  + S ++       S  G+ + G+G 
Sbjct: 293 SLGHGRQGSGSRQSPSHVRHGSGSGHSSS-HGQHGSGSSYSYSRGHYESGSGQTS-GFGQ 350

Query: 180 SQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDADSESDNSDNNTIFVQ 239
            + G     GY K G G    SS G  G           G  + +     +S  ++ + Q
Sbjct: 351 HESGSGQSSGYSKHGSGSGHSSSQGQHGSTS--------GQASSSGQHGSSSRQSSSYGQ 402

Query: 240 GLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATVSFDDPPSAKAA 299
                  +   G+     G    + + G       +    G   G ++ S    P    +
Sbjct: 403 HESASRHSSGRGQHSSGSGQSPGHGQRGSGSGQSPSSGQHGTGFGRSSSS---GPYVSGS 459

Query: 300 IDWFDGKEFHGNIIKVSFATRRPEFMRGGGSGGGRRG-RGGYRGRGGFQGRGGDPKSGDW 358
             +  G   H +  + S    +     G  SG G+ G R G   RG  QG      S   
Sbjct: 460 -GYSSGFGHHESSSEHSSGYTQHGSGSGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYG 518

Query: 359 VCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGRGGRGGDRGGY 418
              + S  ++  +R  S      P P   R   G  +   Y G  GY    GR   RG Y
Sbjct: 519 QHGSGSRQSLGHSRHGS-GSGQSPSPSRGRHESGSRQSSSY-GPHGY--GSGRSSSRGPY 574

Query: 419 GGDRSGGGYGGDRSSGGGYSGDRSG--GGYGGDRSGGGYGGDRG--GGYGGDRG--GGYG 472
               SG G+    SSG G+   RSG   GYG   S  G+    G  G   G     G +G
Sbjct: 575 ---ESGSGH----SSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHG 627

Query: 473 GDRGGGYGGDRGGYGGDRGGGYG--GDRGGYGGDRGGYGGDRG---GYGGDRGGYGGDRS 527
              G      + G G  +   YG  G   G    RG +G D G    YG    G G   S
Sbjct: 628 ATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSSS 687

Query: 528 RGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDRGGGY--GGDRGGYGGK 576
            G +G   G  SG+G     G     S  G G     GY   G R G   +
Sbjct: 688 NGPHGSVSGQSSGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSSR 738



 Score =  121 bits (303), Expect = 2e-27
 Identities = 165/609 (27%), Positives = 210/609 (34%), Gaps = 106/609 (17%)

Query: 2    SDSGSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQN--YSGYSSYGQ- 58
            S SG +G   GE    S +G+  S     +S S  G G    S YGQ+   SG SS G+ 
Sbjct: 2092 SSSGQHGPGLGES---SGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGER 2148

Query: 59   --SQSGYSQSYGGY-ENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDS 115
              S SG S  YG +    +QSS   +  +  G   +    GS  G + S+ Q   G   S
Sbjct: 2149 HGSSSGSSSRYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGSGHSSSHGQHGSGSGRS 2208

Query: 116  -----YDQQSGYD----QHQGSYDEQSNYDQQHDSYSQ---NQQSYHSQRENYSHHTQDD 163
                 Y+ +SG+     QH+      S Y  QH S S    +Q  + S     S   Q+ 
Sbjct: 2209 SSRGPYESRSGHSSVFGQHESGSGHSSAY-SQHGSGSGHFCSQGQHGSTSGQSSTFDQEG 2267

Query: 164  RRDVSRYGEDNRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTD 223
                        G G SQ    G+ G    G+ P  G  G   G   ++G H   G  + 
Sbjct: 2268 SSTGQSSSHGQHGSGSSQSSSYGQQG-SGSGQSPSRGRHGSGSGHSSSYGQH---GSGSG 2323

Query: 224  ADSESDNSDNNTIFVQGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPK 283
              S S    + +    G G   S+      + Q G       +G    + Y         
Sbjct: 2324 WSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHG-------SGSGHSSSY--------- 2367

Query: 284  GEATVSFDDPPSAKAAIDWFDGKEFHGNIIKVSFATRRPEFMRG--GGSGGGRRGRGGYR 341
                                   E HG        +R  +  RG   GS  G     G  
Sbjct: 2368 -----------------------EQHG--------SRSGQSSRGERHGSSSGSSSSYGQH 2396

Query: 342  GRGGFQGRG-GDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRG---R 397
            G G  Q  G G   SG    P+PS G       +   Q +   P  S       RG    
Sbjct: 2397 GSGSRQSLGHGQHGSGSGQSPSPSRGR----HGSGSGQSSSYSPYGSGSGWSSSRGPYES 2452

Query: 398  GYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSG----- 452
            G G   G   R  R G   GYG   S  G+       G  SG  S  G  G  SG     
Sbjct: 2453 GSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSH 2512

Query: 453  --GGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGG 510
               G G  +  GY G +G G G   G G    + G G  +   YG  R G G  R    G
Sbjct: 2513 GQHGSGSSQSSGY-GRQGSGSGQSPGHG----QRGSGSRQSPSYG--RHGSGSGRSSSSG 2565

Query: 511  DRGGYGGDRGGYGGDRSRGGYG---GDRGGGSGYGGDRSGGYG--GDRSGGGYGGDRGGG 565
              G   G+  G+G   S  G        G GSG+    S GYG  G RSG    G+R G 
Sbjct: 2566 QHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGH----SSGYGQHGSRSGQSSRGERHGS 2621

Query: 566  YGGDRGGYG 574
              G    YG
Sbjct: 2622 SSGSSSHYG 2630



 Score =  120 bits (302), Expect = 3e-27
 Identities = 174/635 (27%), Positives = 218/635 (34%), Gaps = 121/635 (19%)

Query: 2    SDSGSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQN--YSGYSSYGQ- 58
            S SG +G   GE    S +G+  S     +S S  G G    S YGQ+   SG SS G+ 
Sbjct: 1152 SSSGQHGSGLGES---SGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGER 1208

Query: 59   --SQSGYSQSYGGY-ENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDS 115
              S SG S  YG +    +QSS   +  +  G   +    GS  G + S+ Q   G   S
Sbjct: 1209 HGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGLGHSSSHGQHGSGSGRS 1268

Query: 116  -----YDQQSGYD----QHQGSYDEQSNYDQQHDS-----YSQNQQSYHSQRENYSHHTQ 161
                 Y+ +SG+     QH+      S Y  QH S      SQ Q    S + +      
Sbjct: 1269 SSRGPYESRSGHSSVFGQHESGSGHSSAY-SQHGSGSGHFCSQGQHGSTSGQSSTFDQEG 1327

Query: 162  DDRRDVSRYGEDNRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPR 221
                  S YG  +RG G SQ  G GR G    G+ P  G  G   G   ++G H   G  
Sbjct: 1328 SSTGQSSSYG--HRGSGSSQSSGYGRHGAG-SGQSPSRGRHGSGSGHSSSYGQH---GSG 1381

Query: 222  TDADSESDNSDNNTIFVQGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGK 281
            +   S S    + +    G G   S+        Q G       +G    + Y       
Sbjct: 1382 SGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGCTQHG-------SGSGHSSSY------- 1427

Query: 282  PKGEATVSFDDPPSAKAAIDWFDGKEFHGNIIKVSFATRRPEFMRG--GGSGGGRRGRGG 339
                                     E HG        +R  +  RG   GS  G     G
Sbjct: 1428 -------------------------EQHG--------SRSGQSSRGERHGSSSGSSSSYG 1454

Query: 340  YRGRGGFQGRG-GDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRG-- 396
              G G  Q  G G   SG    P+PS G       +   Q +   P  S       RG  
Sbjct: 1455 QHGSGSRQSLGHGQHGSGSGQSPSPSRGR----HGSGSGQSSSYSPYGSGSGWSSSRGPY 1510

Query: 397  -RGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSG--- 452
              G     G   R  R G   GYG   S  G+       G  SG  S  G  G  SG   
Sbjct: 1511 ESGSSHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSS 1570

Query: 453  ----GGYGGDRGGGYGGDRGGGYG-----GDRGGG------YGGDRGGYG-----GDRGG 492
                 G G  +  GY G +G G G     G RG G      YG    G G     G  G 
Sbjct: 1571 SHGQHGSGSSQSSGY-GRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGS 1629

Query: 493  GYGGDRGGYGGDRGGYG-----GDRGGYGGDRGGYGGDRSRGGYG--GDRGGGSGYGGDR 545
            G  G+  G+G      G        G   G   GYG   SR G    G+R G S     R
Sbjct: 1630 GL-GESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSRSSSR 1688

Query: 546  SGGYG-GDRSGGGYGGD-RGGGYGGDRGGYGGKMG 578
             G +G G R   G+G    G G    RG +G  +G
Sbjct: 1689 YGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLG 1723



 Score =  120 bits (301), Expect = 4e-27
 Identities = 150/587 (25%), Positives = 190/587 (32%), Gaps = 72/587 (12%)

Query: 4   SGSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQ----TTDSSYGQNY----SGYSS 55
           SGS   SG  Q   S+  + G   +G  S   SGYGQ    +  SS G+ +       SS
Sbjct: 223 SGSGQSSGFSQHKSSSGQSSGYSQHGSGSGHSSGYGQHGSRSGQSSRGERHRSSSGSSSS 282

Query: 56  YGQSQSGYSQSYGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDS 115
           YGQ  SG  QS G +  Q   S     +   G      SS  Q G   SY       +  
Sbjct: 283 YGQHGSGSRQSLG-HGRQGSGSRQSPSHVRHGSGSGHSSSHGQHGSGSSYSYSRGHYESG 341

Query: 116 YDQQSGYDQHQGSYDEQSNYDQQHD----SYSQNQQSYHSQRENYSHHTQDDRRDVSRYG 171
             Q SG+ QH+    + S Y +       S SQ Q    S + + S       R  S YG
Sbjct: 342 SGQTSGFGQHESGSGQSSGYSKHGSGSGHSSSQGQHGSTSGQASSSGQHGSSSRQSSSYG 401

Query: 172 EDNRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDADSESDNS 231
           +       S G G+   G    G+ P  G  G   G   + G H   G      S S   
Sbjct: 402 QHESASRHSSGRGQHSSG---SGQSPGHGQRGSGSGQSPSSGQH---GTGFGRSSSSGPY 455

Query: 232 DNNTIFVQGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATVSFD 291
            + + +  G G   S+ +    + Q G                    +G   G       
Sbjct: 456 VSGSGYSSGFGHHESSSEHSSGYTQHG------------------SGSGHSSGHGQ---- 493

Query: 292 DPPSAKAAIDWFDGKEFHGNIIKVSFATRRPEFMRGGGSGGGRRGRGGYRGRGGFQGRGG 351
                            HG+    S    R     G  S  G+ G G  +  G    R G
Sbjct: 494 -----------------HGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLG--HSRHG 534

Query: 352 DPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGRGGR 411
              SG    P+PS G      R S +            S G +   G G   G   +  R
Sbjct: 535 ---SGSGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYES-GSGHSSGLGHQESR 590

Query: 412 GGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSG--GGYGGDRGGGYGGDRGG 469
            G   GYG   S  G+       G  SG  S  G  G  SG    +G    G     R G
Sbjct: 591 SGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGATSGQSSSHGQHGSGSSQSSRYG 650

Query: 470 GYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRG 529
             G   G G    RG +G D G      + G G       G  G   G   G+G     G
Sbjct: 651 QQGS--GSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSSSNGPHGSVSGQSSGFGHKSGSG 708

Query: 530 GYGGDRGGGSGYGGDRSGGY--GGDRSGGGYGGDRGGGYGGDRGGYG 574
              G    GS  G   S GY   G RSG     ++ G   G    YG
Sbjct: 709 QSSGYSQHGS--GSSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYG 753



 Score =  118 bits (296), Expect = 1e-26
 Identities = 154/629 (24%), Positives = 219/629 (34%), Gaps = 91/629 (14%)

Query: 2    SDSGSYGQSGGEQQSYSTYGNPGSQGY---GQASQSYSGYGQTTDSSYGQNYSGYSSYGQ 58
            S  G Y    G+   +  + +   QGY   G AS  +S  G+   +S GQ+ S  S    
Sbjct: 802  SSCGHYESGSGQASGFGQHESGSGQGYSQHGSASGHFSSQGRHGSTS-GQSSS--SGQHD 858

Query: 59   SQSGYSQSYGGYENQKQSSYSQQPYNN-QGQQQNMESSGSQGGRAPSYDQ---------- 107
            S SG S SYG +E+    +  +  + +  GQ       GS  G++PSY +          
Sbjct: 859  SSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGSGSGQSPSYGRHGSGSGRSSS 918

Query: 108  -----------PDYGQQDSYDQQSGYDQHQGSYDEQSNYDQQ-----HDSYSQNQQSYHS 151
                         +G + S  Q SGY QH       S+Y+Q        S S+   S   
Sbjct: 919  SGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRSEQHGSSSG 978

Query: 152  QRENYSHHTQDDRRDVSRYGEDNRGYGGSQGGGRGR---GGYDKDGRGPMTGSSG--GDR 206
               +Y  H    R+ +  +G+   G G S    RGR   G       GP    SG    R
Sbjct: 979  SSSSYGQHGSGSRQSLG-HGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYRSGSGWSSSR 1037

Query: 207  GGFKNFGGHRD-YGPRTDADSESDNSDNNTIFVQGLGEGVSTDQVGEFFKQIGIIKTNKK 265
            G +++  GH    G R     +S           G G+  S+        Q G       
Sbjct: 1038 GPYESGSGHSSGLGHRESRSGQS----------SGYGQHGSSSGHSSTHGQHG-----ST 1082

Query: 266  TGKPMINLYTDKDTGKPKGEATVSFDDPPSAKAAIDWFDGKEFHGNIIKVSFATRRPEFM 325
            +G+          +G+             S+          +  G+  + S + + P + 
Sbjct: 1083 SGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYG 1142

Query: 326  RGGGSGGGRRGRGGYRGRGGFQGRG-GDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRP 384
            R  GSG GR    G  G G  +  G G  +S        S  + ++++  S +  +    
Sbjct: 1143 R-HGSGSGRSSSSGQHGSGLGESSGFGHHESS-------SGQSSSYSQHGSGSGHSSGYG 1194

Query: 385  EDSRPSGGDFRGRGYGGERGYRGRGGR--GGDRGGYGGDRSGGGYGGDRSSGGGYSGDRS 442
            +    SG   RG  +G   G     G+   G R   G  R G G G   S G   SG   
Sbjct: 1195 QHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGLGH 1254

Query: 443  GGGYGGDRSGGGYGGDRG-----GGYGG-----DRGGGYG---GDRGGGYG-----GDRG 484
               +G   SG G    RG      G+       + G G+       G G G     G  G
Sbjct: 1255 SSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHG 1314

Query: 485  GYGG-----DRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGS 539
               G     D+ G   G    Y G RG       GYG    G G   SRG +G   G  S
Sbjct: 1315 STSGQSSTFDQEGSSTGQSSSY-GHRGSGSSQSSGYGRHGAGSGQSPSRGRHGSGSGHSS 1373

Query: 540  GYGGDRSG-GYGGDRSGGGYGGDRGGGYG 567
             YG   SG G+       G G  +  G+G
Sbjct: 1374 SYGQHGSGSGWSSSSGRHGSGSGQSSGFG 1402



 Score =  117 bits (294), Expect = 2e-26
 Identities = 163/609 (26%), Positives = 208/609 (34%), Gaps = 106/609 (17%)

Query: 2    SDSGSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQN--YSGYSSYGQS 59
            S SG +G   GE    S +G+  S     +S S  G G    S YGQ+   SG SS G+ 
Sbjct: 1622 SSSGQHGSGLGES---SGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGER 1678

Query: 60   QSGYSQSYGGY----ENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDS 115
                S+S   Y       +QSS   +  +  GQ  +    GS  G + S+ Q   G   S
Sbjct: 1679 HGSSSRSSSRYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRS 1738

Query: 116  -----YDQQSGYD----QHQGSYDEQSNYDQQHDSYSQ---NQQSYHSQRENYSHHTQDD 163
                 Y+ +SG+     QH+      S Y  QH S S    +Q  + S     S   Q+ 
Sbjct: 1739 SSRGPYESRSGHSSVFGQHESGSGHSSAY-SQHGSGSGHFCSQGQHGSTSGQSSTFDQEG 1797

Query: 164  RRDVSRYGEDNRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTD 223
                        G G SQ    G+ G    G+ P  G  G   G   ++G H   G  + 
Sbjct: 1798 SSTGQSSSHGQHGSGSSQSSSYGQQG-SGSGQSPSRGRHGSGSGHSSSYGQH---GSGSG 1853

Query: 224  ADSESDNSDNNTIFVQGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPK 283
              S S    + +    G G   S+      + Q G       +G    + Y         
Sbjct: 1854 WSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHG-------SGSGHSSSY--------- 1897

Query: 284  GEATVSFDDPPSAKAAIDWFDGKEFHGNIIKVSFATRRPEFMRG--GGSGGGRRGRGGYR 341
                                   E HG        +R  +  RG   GS  G     G  
Sbjct: 1898 -----------------------EQHG--------SRSGQSSRGEQHGSSSGSSSSYGQH 1926

Query: 342  GRGGFQGRG-GDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRG---R 397
            G G  Q  G G   SG    P+PS G       +   Q +   P  S       RG    
Sbjct: 1927 GSGSRQSLGHGQHGSGSGQSPSPSRGR----HGSGSGQSSSYGPYGSGSGWSSSRGPYES 1982

Query: 398  GYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSG----- 452
            G G   G   R  R G   GYG   S  G+       G  SG  S  G  G  SG     
Sbjct: 1983 GSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSSSH 2042

Query: 453  --GGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGG 510
               G G  +  GY G +G G G   G G    + G G  +   YG  R G G  R    G
Sbjct: 2043 GQHGSGSSQSSGY-GRQGSGSGQSPGHG----QRGSGSRQSPSYG--RHGSGSGRSSSSG 2095

Query: 511  DRGGYGGDRGGYGGDRSRGGYG---GDRGGGSGYGGDRSGGYG--GDRSGGGYGGDRGGG 565
              G   G+  G+G   S  G        G GSG+    S GYG  G RSG    G+R G 
Sbjct: 2096 QHGPGLGESSGFGHHESSSGQSSSYSQHGSGSGH----SSGYGQHGSRSGQSSRGERHGS 2151

Query: 566  YGGDRGGYG 574
              G    YG
Sbjct: 2152 SSGSSSRYG 2160



 Score =  115 bits (289), Expect = 9e-26
 Identities = 159/605 (26%), Positives = 212/605 (35%), Gaps = 72/605 (11%)

Query: 30  QASQSYSGYGQTTDSSYGQNYSGYSSYGQSQSGYSQSYGGYENQKQSSYSQQP--YNNQG 87
           ++S S+S +    + SY +N  G    G        S+    + + +SYS Q   Y  Q 
Sbjct: 124 ESSFSHSSWSAGENDSYSRNVRGSLKPGTESISRRLSFQRDFSGQHNSYSGQSSSYGEQN 183

Query: 88  QQQNMESSGSQGGRAPSYDQPDYGQQDSYDQQSGYDQHQGSYDEQSNYDQQHDSYSQNQQ 147
              +  S   Q G   S   P+YGQ  S   QS  +   GS   QS+   QH S S  Q 
Sbjct: 184 SDSHQSSGRGQCGSG-SGQSPNYGQHGSGSGQSSSNDTHGSGSGQSSGFSQHKS-SSGQS 241

Query: 148 SYHSQRENYSHHTQDDRRDVSRYGEDNRG------------YGGSQGGGRGRGGYDKDGR 195
           S +SQ  + S H+    +  SR G+ +RG            YG    G R   G+ + G 
Sbjct: 242 SGYSQHGSGSGHSSGYGQHGSRSGQSSRGERHRSSSGSSSSYGQHGSGSRQSLGHGRQGS 301

Query: 196 GPMTGSSGGDRG-GFKNFGGHRDYGPRTDADSESDNSDNNTIFVQGLGEGVSTDQVGEFF 254
           G     S    G G  +   H  +G      S S  S +   +  G G+   T   G+  
Sbjct: 302 GSRQSPSHVRHGSGSGHSSSHGQHG------SGSSYSYSRGHYESGSGQ---TSGFGQHE 352

Query: 255 KQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATVSFDDPPSAKAAIDWFDGKEFHGNIIK 314
              G      K G    +  +    G   G+A+ S     S++ +  +      H +  +
Sbjct: 353 SGSGQSSGYSKHGSGSGHSSSQGQHGSTSGQASSSGQHGSSSRQSSSYGQ----HESASR 408

Query: 315 VSFATRRPEFMRGGGSGGGRRGRG-GYRGRGGFQGRGGDPKSGDWVCPNPSCGNMNFARR 373
            S    +     G   G G+RG G G     G  G G    S      + S  +  F   
Sbjct: 409 HSSGRGQHSSGSGQSPGHGQRGSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYSSGFGHH 468

Query: 374 NSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGRGGRGGDRGG----YG----GDR--- 422
            S ++ +    +    SG       +G   G   RG R G   G    YG    G R   
Sbjct: 469 ESSSEHSSGYTQHGSGSGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSL 528

Query: 423 ------SGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRG---GGYGGDRGGGYGG 473
                 SG G     S G   SG R    YG    G G    RG    G G   G G+  
Sbjct: 529 GHSRHGSGSGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQE 588

Query: 474 DRGG---GYG--GDRGGYG---GDRGGGYG-----GDRGGYGGDRGGYGGDRGG------ 514
            R G   GYG  G   G+    G  G   G     G  G   G    +G    G      
Sbjct: 589 SRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGATSGQSSSHGQHGSGSSQSSR 648

Query: 515 YGGDRGGYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDRGGGYG-GDRGGY 573
           YG    G G   SRG +G D G  S YG   SG  G   S G +G   G   G G + G 
Sbjct: 649 YGQQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGS-GWSSSNGPHGSVSGQSSGFGHKSGS 707

Query: 574 GGKMG 578
           G   G
Sbjct: 708 GQSSG 712



 Score =  115 bits (288), Expect = 1e-25
 Identities = 157/621 (25%), Positives = 207/621 (33%), Gaps = 99/621 (15%)

Query: 10  SGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSS-YGQSQSGYSQSYG 68
           S GE  SYS     GS   G  S S     Q   S    +YSG SS YG+  S   QS G
Sbjct: 133 SAGENDSYSRNVR-GSLKPGTESISRRLSFQRDFSGQHNSYSGQSSSYGEQNSDSHQSSG 191

Query: 69  GYENQKQSSYSQQPYNNQ-----GQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQQSGYD 123
               Q  S   Q P   Q     GQ  + ++ GS  G++  + Q     + S  Q SGY 
Sbjct: 192 --RGQCGSGSGQSPNYGQHGSGSGQSSSNDTHGSGSGQSSGFSQ----HKSSSGQSSGYS 245

Query: 124 QHQGSYDEQSNYDQQ-----HDSYSQNQQSYHSQRENYSHHTQDDRRDVSRYGEDNRGYG 178
           QH       S Y Q        S  +  +S      +Y  H    R+ +        G+G
Sbjct: 246 QHGSGSGHSSGYGQHGSRSGQSSRGERHRSSSGSSSSYGQHGSGSRQSL--------GHG 297

Query: 179 GSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFG---GHRDYGPRTDA---DSESDNSD 232
               G R    + + G G    SS G  G   ++    GH + G    +     ES +  
Sbjct: 298 RQGSGSRQSPSHVRHGSGSGHSSSHGQHGSGSSYSYSRGHYESGSGQTSGFGQHESGSGQ 357

Query: 233 NNTIFVQGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATVSFDD 292
           ++     G G G S+ Q                              G   G+A+ S   
Sbjct: 358 SSGYSKHGSGSGHSSSQ---------------------------GQHGSTSGQASSSGQH 390

Query: 293 PPSAKAAIDWFDGKEFHGNIIKVSFATRRPEFMRGGGSGGGRRGRG-GYRGRGGFQGRGG 351
             S++ +  +      H +  + S    +     G   G G+RG G G     G  G G 
Sbjct: 391 GSSSRQSSSYGQ----HESASRHSSGRGQHSSGSGQSPGHGQRGSGSGQSPSSGQHGTGF 446

Query: 352 DPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGRGGR 411
              S      + S  +  F    S ++ +    +    SG       +G   G   RG R
Sbjct: 447 GRSSSSGPYVSGSGYSSGFGHHESSSEHSSGYTQHGSGSGHSSGHGQHGSRSGQSSRGER 506

Query: 412 GGDRGG----YG----GDR---------SGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGG 454
            G   G    YG    G R         SG G     S G   SG R    YG    G G
Sbjct: 507 QGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSPSPSRGRHESGSRQSSSYGPHGYGSG 566

Query: 455 YGGDRG---GGYGGDRGGGYGGDRGG---GYGGDRGGYGGDRGGGYGGDRGGYGGDRGGY 508
               RG    G G   G G+   R G   GYG      G     G  G   G     G +
Sbjct: 567 RSSSRGPYESGSGHSSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQH 626

Query: 509 GGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSG-------YGGD--RSGGYGGDRSGGGYG 559
           G    G     G +G   S+    G +G GSG       +G D   S  YG   SG G+ 
Sbjct: 627 GA-TSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGSGWS 685

Query: 560 GDRG--GGYGGDRGGYGGKMG 578
              G  G   G   G+G K G
Sbjct: 686 SSNGPHGSVSGQSSGFGHKSG 706



 Score =  114 bits (285), Expect = 3e-25
 Identities = 159/632 (25%), Positives = 219/632 (34%), Gaps = 84/632 (13%)

Query: 2    SDSGS---YGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGY---SS 55
            S SGS   YGQ G   +  S +G  GS      S+   G G    SS+GQ+ SG    SS
Sbjct: 2151 SSSGSSSRYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGSGHSSSHGQHGSGSGRSSS 2210

Query: 56   YG--QSQSGYSQSYGGYENQK--QSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYG 111
             G  +S+SG+S  +G +E+     S+YSQ   +  G   +    GS  G++ ++DQ    
Sbjct: 2211 RGPYESRSGHSSVFGQHESGSGHSSAYSQHG-SGSGHFCSQGQHGSTSGQSSTFDQ---- 2265

Query: 112  QQDSYDQQSGYDQHQGSYDEQSNYDQQHDSYSQN-QQSYHSQRENYSHHTQDDRRDVSRY 170
            +  S  Q S + QH     + S+Y QQ     Q+  +  H     +S          S Y
Sbjct: 2266 EGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHS----------SSY 2315

Query: 171  GEDNRGYGGSQGGGR-GRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDADSESD 229
            G+   G G S   GR G G     G G    SS    G  ++  G           S S 
Sbjct: 2316 GQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSG 2375

Query: 230  NSDNNTIFVQGLGEGVSTDQVGEFFKQ-IGIIKTNKKTGKPMINLYTDKDTGKPKGEATV 288
             S          G   S  Q G   +Q +G  +    +G+          +G  +  +  
Sbjct: 2376 QSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYS 2435

Query: 289  SFDDPPSAKAAIDWFDGKEFHGNIIKVSFATRRPEFMRGGGSGGGRRGRGGYRGRGGFQG 348
             +       ++   ++    H      S      E   G  SG G+ G     G     G
Sbjct: 2436 PYGSGSGWSSSRGPYESGSGH------SSGLGHRESRSGQSSGYGQHGSSS--GHSSTHG 2487

Query: 349  RGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYG-----GER 403
            + G          + SCG    +   S +   +     S+ SG   +G G G     G+R
Sbjct: 2488 QHGSTSG-----QSSSCGQHGASSGQSSSH-GQHGSGSSQSSGYGRQGSGSGQSPGHGQR 2541

Query: 404  GYR-------GRGGRG--------------GDRGGYGGDRSGGGYGGDRSSGGGYSGDRS 442
            G         GR G G              G+  G+G   S  G     S  G  SG  S
Sbjct: 2542 GSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSS 2601

Query: 443  GGGYGGDRSGGGYGGDRGGGYGGDRG----GGYGGDRGGGYGGDRGGYGGDRGGGYGGDR 498
            G G  G RSG    G+R G   G        G G  +  G+G    G G     G  G  
Sbjct: 2602 GYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSG 2661

Query: 499  GGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSGYG------GDRSG----- 547
             G+    G +G    G    RG Y          G    GSG+       G  SG     
Sbjct: 2662 LGHSSSHGQHGSG-SGRSSSRGPYESRLGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQ 2720

Query: 548  GYGGDRSGGGYGGDRGGGYGGDRGGYGGKMGG 579
            G  G  SG     D+ G   G    YG +  G
Sbjct: 2721 GQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSG 2752



 Score =  112 bits (279), Expect = 1e-24
 Identities = 154/614 (25%), Positives = 215/614 (35%), Gaps = 80/614 (13%)

Query: 4    SGSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGY---SSYG--Q 58
            S  YGQ G   +  S +G  GS      S+   G G    SS+GQ+ SG    SS G  +
Sbjct: 1686 SSRYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYE 1745

Query: 59   SQSGYSQSYGGYENQK--QSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSY 116
            S+SG+S  +G +E+     S+YSQ   +  G   +    GS  G++ ++DQ    +  S 
Sbjct: 1746 SRSGHSSVFGQHESGSGHSSAYSQHG-SGSGHFCSQGQHGSTSGQSSTFDQ----EGSST 1800

Query: 117  DQQSGYDQHQGSYDEQSNYDQQHDSYSQN-QQSYHSQRENYSHHTQDDRRDVSRYGEDNR 175
             Q S + QH     + S+Y QQ     Q+  +  H     +S          S YG+   
Sbjct: 1801 GQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHS----------SSYGQHGS 1850

Query: 176  GYGGSQGGGR-GRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDADSESDNSDNN 234
            G G S   GR G G     G G    SS    G  ++  G           S S  S   
Sbjct: 1851 GSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRG 1910

Query: 235  TIFVQGLGEGVSTDQVGEFFKQ-IGIIKTNKKTGKPMINLYTDKDTGKPKGEATVSFDDP 293
                   G   S  Q G   +Q +G  +    +G+          +G  +  +   +   
Sbjct: 1911 EQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYGSG 1970

Query: 294  PSAKAAIDWFDGKEFHGNIIKVSFATRRPEFMRGGGSGGGRRGRGGYRGRGGFQGRGGDP 353
                ++   ++    H      S      E   G  SG G+ G     G     G+ G  
Sbjct: 1971 SGWSSSRGPYESGSGH------SSGLGHRESRSGQSSGYGQHGSSS--GHSSTHGQHGSA 2022

Query: 354  KSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYG-----GERGYR-- 406
                    + SCG    +   S +   +     S+ SG   +G G G     G+RG    
Sbjct: 2023 SG-----QSSSCGQHGASSGQSSSH-GQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSR 2076

Query: 407  -----GRGGRG--------------GDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYG 447
                 GR G G              G+  G+G   S  G     S  G  SG  SG G  
Sbjct: 2077 QSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQH 2136

Query: 448  GDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGG 507
            G RSG    G+R G   G             YG    G     G G  G   G+   RG 
Sbjct: 2137 GSRSGQSSRGERHGSSSGS---------SSRYGQHGSGSRQSSGHGRQGSGSGHSPSRGR 2187

Query: 508  YG---GDRGGYGGDRGGYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDRGG 564
            +G   G    +G    G G   SRG Y   R G S   G    G G   +   +G   G 
Sbjct: 2188 HGSGSGHSSSHGQHGSGSGRSSSRGPY-ESRSGHSSVFGQHESGSGHSSAYSQHGS--GS 2244

Query: 565  GYGGDRGGYGGKMG 578
            G+   +G +G   G
Sbjct: 2245 GHFCSQGQHGSTSG 2258



 Score =  111 bits (277), Expect = 2e-24
 Identities = 154/610 (25%), Positives = 214/610 (35%), Gaps = 95/610 (15%)

Query: 7    YGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQSQSGYSQS 66
            +G S G   SY  +G+   Q  G   Q  SG GQ+   S G++ SG        SG S S
Sbjct: 1913 HGSSSGSSSSYGQHGSGSRQSLGHG-QHGSGSGQSPSPSRGRHGSG--------SGQSSS 1963

Query: 67   YGGYENQKQSSYSQQPYNN-QGQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQQSGYDQH 125
            YG Y +    S S+ PY +  G    +    S+ G++  Y Q  +G    +    G  QH
Sbjct: 1964 YGPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQ--HGSSSGHSSTHG--QH 2019

Query: 126  QGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSRYGED----NRGYGGSQ 181
             GS   QS+   QH + S  Q S H Q  + S  +    R  S  G+      RG G  Q
Sbjct: 2020 -GSASGQSSSCGQHGA-SSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQ 2077

Query: 182  GGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDADSESDNSDNNTIFVQGL 241
                GR G    GR   +G  G   G    FG H           ES +  +++    G 
Sbjct: 2078 SPSYGRHG-SGSGRSSSSGQHGPGLGESSGFGHH-----------ESSSGQSSSYSQHGS 2125

Query: 242  GEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATVSFDDPPSAKAAID 301
            G G S+          G  +   ++G+           G+  G ++ S     S++    
Sbjct: 2126 GSGHSS----------GYGQHGSRSGQ--------SSRGERHGSSSGS-----SSRYGQH 2162

Query: 302  WFDGKEFHGNIIKVSFATRRPEFMRGG------------GSGGGRRG-RGGYRGRGGFQG 348
                ++  G+  + S +   P   R G            GSG GR   RG Y  R G   
Sbjct: 2163 GSGSRQSSGHGRQGSGSGHSPSRGRHGSGSGHSSSHGQHGSGSGRSSSRGPYESRSGHSS 2222

Query: 349  RGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGR 408
              G  +SG     + +         + C+Q  +      + S  D  G   G    +   
Sbjct: 2223 VFGQHESGSG--HSSAYSQHGSGSGHFCSQ-GQHGSTSGQSSTFDQEGSSTGQSSSHGQH 2279

Query: 409  GGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGG-------GYGGDRGG 461
            G        YG   SG G    R   G  SG  S  G  G  SG        G G  +  
Sbjct: 2280 GSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSS 2339

Query: 462  GYGGDRGGGYGGD------RGGGYGGDRGGYGGDRGGGYGGDR-GGYGGDRGGYG----G 510
            G+G      +          G G+      +G   G    G+R G   G    YG    G
Sbjct: 2340 GFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSG 2399

Query: 511  DRGGYGGDRGGYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDRGGGYGGDR 570
             R   G  + G G  +S     G  G GSG    +S  Y    SG G+   RG    G  
Sbjct: 2400 SRQSLGHGQHGSGSGQSPSPSRGRHGSGSG----QSSSYSPYGSGSGWSSSRGPYESG-- 2453

Query: 571  GGYGGKMGGR 580
             G+   +G R
Sbjct: 2454 SGHSSGLGHR 2463



 Score =  110 bits (274), Expect = 5e-24
 Identities = 170/686 (24%), Positives = 226/686 (32%), Gaps = 126/686 (18%)

Query: 4    SGSYGQSGGEQQSYSTYGNPGSQGYGQASQSYS-GYGQTTDSSYGQNYSGY---SSYGQS 59
            S  Y Q G      S Y   GS+  GQ+S+S   G      SSYGQ+ SG    S +G+ 
Sbjct: 710  SSGYSQHGSGSSHSSGYRKHGSRS-GQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQ 768

Query: 60   QSGYSQSYGGYENQKQSSYSQQPYNNQGQQQNMESS----GSQGGRAPSYDQPDYGQQDS 115
             SG   S     +   S +S   +   G   +  SS     S  G+A  + Q + G    
Sbjct: 769  GSGSGHSPSRVRHGSSSGHSSS-HGQHGSGTSCSSSCGHYESGSGQASGFGQHESGSGQG 827

Query: 116  YDQQSGYDQH------QGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSR 169
            Y Q      H       GS   QS+   QHDS S  Q S + Q E+ SHH     R  S 
Sbjct: 828  YSQHGSASGHFSSQGRHGSTSGQSSSSGQHDS-SSGQSSSYGQHESASHHASGRGRHGSG 886

Query: 170  YGED----NRGYGGSQ-------GGGRGRG---GYDKDGRGPMTG----SSGGDRGGFKN 211
             G+      RG G  Q       G G GR    G    G G  +G    SS G   G+  
Sbjct: 887  SGQSPGHGQRGSGSGQSPSYGRHGSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQ 946

Query: 212  FG---GH----RDYGPRT-----------DADSESDNSDNNTIFVQGLGEGVSTDQVGEF 253
             G   GH      +G R+            + S S    + +   Q LG G      G+ 
Sbjct: 947  HGSGSGHSSSYEQHGSRSGQSSRSEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQ- 1005

Query: 254  FKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATVSFDDPPSAKAAIDWFDGKEF----- 308
                   +    +G    + Y    +G     +   ++      + +   + +       
Sbjct: 1006 --SPSPSRGRHGSGSGQSSSYGPYRSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGY 1063

Query: 309  ---------------HGNIIKVSFATRRPEFMRGGGSGGGRRGRGGYRGRG-GFQGRGGD 352
                           HG+    S +  +     G  S  G+ G G  +  G G QG G  
Sbjct: 1064 GQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSG 1123

Query: 353  PKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGRGGRG 412
               G     + S  + ++ R  S +          R S     G G G   G+       
Sbjct: 1124 QSPGHGQRGSGSRQSPSYGRHGSGS---------GRSSSSGQHGSGLGESSGFGHHESSS 1174

Query: 413  GDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYG-----GDRGGGYGGDR 467
            G    Y    SG G+    SSG G  G RSG    G+R G   G     G  G G     
Sbjct: 1175 GQSSSYSQHGSGSGH----SSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSS 1230

Query: 468  GGGYGGDRGGGYGGDRGGYGGDRGG----GYGGDRGGYGGDRGGY--------------- 508
            G G  G  G G+   RG +G   G     G  G   G    RG Y               
Sbjct: 1231 GHGRQGS-GSGHSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHES 1289

Query: 509  -GGDRGGYGGDRGGYGGDRSRGGYGGDRGGGS-----GYGGDRSGGYG----GDRSGGGY 558
              G    Y     G G   S+G +G   G  S     G    +S  YG    G     GY
Sbjct: 1290 GSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGY 1349

Query: 559  GGD-RGGGYGGDRGGYGGKMGGRNDY 583
            G    G G    RG +G   G  + Y
Sbjct: 1350 GRHGAGSGQSPSRGRHGSGSGHSSSY 1375



 Score =  110 bits (274), Expect = 5e-24
 Identities = 157/609 (25%), Positives = 215/609 (35%), Gaps = 63/609 (10%)

Query: 2    SDSGS---YGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGY---SS 55
            S SGS   YGQ G   +  S +G  GS      S+   G G    SS+GQ+ SG    SS
Sbjct: 1211 SSSGSSSHYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGLGHSSSHGQHGSGSGRSSS 1270

Query: 56   YG--QSQSGYSQSYGGYENQK--QSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYG 111
             G  +S+SG+S  +G +E+     S+YSQ   +  G   +    GS  G++ ++DQ    
Sbjct: 1271 RGPYESRSGHSSVFGQHESGSGHSSAYSQHG-SGSGHFCSQGQHGSTSGQSSTFDQ---- 1325

Query: 112  QQDSYDQQSGYDQHQGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSRYG 171
            +  S  Q S Y  H+GS   QS+   +H + S    S         H         S YG
Sbjct: 1326 EGSSTGQSSSYG-HRGSGSSQSSGYGRHGAGSGQSPSRGRHGSGSGHS--------SSYG 1376

Query: 172  EDNRGYGGSQGGGR-GRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDADSESDN 230
            +   G G S   GR G G     G G    SS    G  ++  G           S S  
Sbjct: 1377 QHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGCTQHGSGSGHSSSYEQHGSRSGQ 1436

Query: 231  SDNNTIFVQGLGEGVSTDQVGEFFKQ-IGIIKTNKKTGKPMINLYTDKDTGKPKGEATVS 289
            S          G   S  Q G   +Q +G  +    +G+          +G  +  +   
Sbjct: 1437 SSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSP 1496

Query: 290  FDDPPSAKAAIDWFDGKEFHGNIIKVSFATRRPEFMRGGGSGGGRRGRGGYRGRGGFQGR 349
            +       ++   ++    H      S      E   G  SG G+ G     G     G+
Sbjct: 1497 YGSGSGWSSSRGPYESGSSH------SSGLGHRESRSGQSSGYGQHGSSS--GHSSTHGQ 1548

Query: 350  GGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGRG 409
             G          + SCG    +   S +   +     S+ SG   +G G G   G+  RG
Sbjct: 1549 HGSTSG-----QSSSCGQHGASSGQSSSH-GQHGSGSSQSSGYGRQGSGSGQSPGHGQRG 1602

Query: 410  ---------GRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRG 460
                     GR G   G        G G   SSG G+    SG      + G G G   G
Sbjct: 1603 SGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSG 1662

Query: 461  GGYGGDRGG-GYGGDRGGG-------YGGDRGGYGGDRGGGYGGDRGGYGGDRGGYG--- 509
             G  G R G    G+R G        YG    G     G G  G   G    RG +G   
Sbjct: 1663 YGQHGSRSGQSSRGERHGSSSRSSSRYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGL 1722

Query: 510  GDRGGYGGDRGGYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDRGGGYGGD 569
            G    +G    G G   SRG Y   R G S   G    G G   +   +G   G G+   
Sbjct: 1723 GHSSSHGQHGSGSGRSSSRGPY-ESRSGHSSVFGQHESGSGHSSAYSQHGS--GSGHFCS 1779

Query: 570  RGGYGGKMG 578
            +G +G   G
Sbjct: 1780 QGQHGSTSG 1788



 Score =  109 bits (273), Expect = 6e-24
 Identities = 162/634 (25%), Positives = 205/634 (32%), Gaps = 96/634 (15%)

Query: 5    GSYGQSGGEQQSYSTYGNPGSQGYGQASQ-SYSGYGQTTDSSYGQNYSGYSSYGQSQSGY 63
            G +    G   +YS +G+       Q    S SG   T D   G +    SS+GQ  SG 
Sbjct: 2225 GQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQE-GSSTGQSSSHGQHGSGS 2283

Query: 64   SQSYGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSYD------ 117
            SQS         SSY QQ  +  GQ  +    GS  G + SY Q   G   S        
Sbjct: 2284 SQS---------SSYGQQG-SGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGS 2333

Query: 118  ---QQSGYDQHQGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRR-----DVSR 169
               Q SG+  H+ S  + S Y  QH S S +  SY          ++ +R        S 
Sbjct: 2334 GSGQSSGFGHHESSSWQSSGY-TQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSS 2392

Query: 170  YGEDNRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRG-GFKNFGGHRDYGPRTDADSES 228
            YG+   G G  Q  G G+ G    G G     S G  G G      +  YG  +   S  
Sbjct: 2393 YGQ--HGSGSRQSLGHGQHG---SGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSR 2447

Query: 229  DNSDNNTIFVQGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATV 288
               ++ +    GLG   S       + Q G    +           T    G   G+++ 
Sbjct: 2448 GPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSS---------THGQHGSTSGQSSS 2498

Query: 289  SFDDPPSAKAAIDWFDGKEFHGNIIKVSFATRRPEFMRGGGSGGGRRGRGGYRGRG-GFQ 347
                  S+  +         HG+    S    R     G   G G+RG G  +    G  
Sbjct: 2499 CGQHGASSGQS----SSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRH 2554

Query: 348  GRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRG 407
            G G    S      +    +  F    S +  +    +    SG       +G   G   
Sbjct: 2555 GSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSS 2614

Query: 408  RGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYG-----GDRGGG 462
            RG R G   G        G G  +SSG G  G  SG      R G G G     G  G G
Sbjct: 2615 RGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSG 2674

Query: 463  YG------------------GDRGGGYG-----GDRGGGYG-----GDRGGYGG-----D 489
             G                  G    G G        G G G     G  G   G     D
Sbjct: 2675 SGRSSSRGPYESRLGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFD 2734

Query: 490  RGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSGYGGDRSG-- 547
            + G   G    Y G RG       GYG    G G   S G +G   G  S YG   SG  
Sbjct: 2735 QEGSSTGQSSSY-GHRGSGSSQSSGYGRHGAGSGQSLSHGRHGSGSGQSSSYGQHGSGSG 2793

Query: 548  ---GYGGDRSGG---GYGGDRGGGY--GGDRGGY 573
               GY    SG    GY   +GG    GG  G Y
Sbjct: 2794 QSSGYSQHGSGSGQDGYSYCKGGSNHDGGSSGSY 2827



 Score =  105 bits (262), Expect = 1e-22
 Identities = 154/641 (24%), Positives = 227/641 (35%), Gaps = 88/641 (13%)

Query: 7   YGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTT-----DSSYGQNYSGYSSYGQSQS 61
           +G   G   S+  +G+  S  Y +     SG GQT+     +S  GQ+ SGYS +G S S
Sbjct: 312 HGSGSGHSSSHGQHGSGSSYSYSRGHYE-SGSGQTSGFGQHESGSGQS-SGYSKHG-SGS 368

Query: 62  GYSQSYGGY---------ENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQ 112
           G+S S G +           Q  SS  Q     Q +  +  SSG     + S   P +GQ
Sbjct: 369 GHSSSQGQHGSTSGQASSSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGSGQSPGHGQ 428

Query: 113 QDSYDQQS----------GYDQHQGSYDEQSNYDQ---QHDSYSQNQQSYHSQRENYSHH 159
           + S   QS          G     G Y   S Y      H+S S++   Y +Q  + S H
Sbjct: 429 RGSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYSSGFGHHESSSEHSSGY-TQHGSGSGH 487

Query: 160 TQDDRRDVSRYGEDNRG------------YGGSQGGGRGRGGYDKDGRGP---MTGSSGG 204
           +    +  SR G+ +RG            YG    G R   G+ + G G     + S G 
Sbjct: 488 SSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSPSPSRGR 547

Query: 205 DRGGFKNFGGHRDYGPRTDADSESDNSDNNTIFVQGLGEGVS----TDQVGEFFKQIGII 260
              G +    +  +G  +   S     ++ +    GLG   S    +   G+     G  
Sbjct: 548 HESGSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQESRSGQSSGYGQHGSSSGHS 607

Query: 261 KTNKKTGKPMINLYTDKDTGKPKGEATVSFDDPPSAKAAIDWFDGKEFHGNIIKVSFATR 320
            T+ + G       +    G   G+++        +  +  +  G++  G+    S    
Sbjct: 608 STHGQHGSTSGQSSSCGQHGATSGQSSSHGQHGSGSSQSSRY--GQQGSGSGQSPSRGRH 665

Query: 321 RPEFMRGG-----GSGGGRRGRGGYRGRGGFQGRGGDPKSGDWVCPNPSCGNMNFARRNS 375
             +F         GSG G     G  G    Q  G   KSG       S  +  +++  S
Sbjct: 666 GSDFGHSSSYGQHGSGSGWSSSNGPHGSVSGQSSGFGHKSG-------SGQSSGYSQHGS 718

Query: 376 CNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGRGGRGGD----RGGYGGDRSGGGYGGDR 431
            +  +    +    SG   R   +G   G     G+ G       G+G   SG G+   R
Sbjct: 719 GSSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPSR 778

Query: 432 SSGGGYSGDRSGGGYGGD-----RSGGGY--GGDRGGGYGG-DRGGGYGGDRGG---GYG 480
              G  SG  S  G  G       S G Y  G  +  G+G  + G G G  + G   G+ 
Sbjct: 779 VRHGSSSGHSSSHGQHGSGTSCSSSCGHYESGSGQASGFGQHESGSGQGYSQHGSASGHF 838

Query: 481 GDRGGYGGDRG-GGYGGDRGGYGGDRGGYGGDRGG--YGGDRGGYGGDRSRGGYGGDRGG 537
             +G +G   G     G      G    YG       +   RG +G    +    G RG 
Sbjct: 839 SSQGRHGSTSGQSSSSGQHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGS 898

Query: 538 GSGYGGDRSGGYGGDRSGGGYGGDRG--GGYGGDRGGYGGK 576
           GSG    +S  YG   SG G     G  G   G   G+G K
Sbjct: 899 GSG----QSPSYGRHGSGSGRSSSSGRHGSGSGQSSGFGHK 935



 Score =  103 bits (257), Expect = 4e-22
 Identities = 150/620 (24%), Positives = 207/620 (33%), Gaps = 67/620 (10%)

Query: 2   SDSGSYGQSGGEQQSYSTYGNPG--SQGYGQAS----------QSYSGYGQTTDSS-YGQ 48
           S SG +G S  +  SY  + +    S G GQ S          Q  SG GQ+  S  +G 
Sbjct: 385 SSSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGSGQSPGHGQRGSGSGQSPSSGQHGT 444

Query: 49  NYSGYSSYGQ--SQSGYSQSYGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYD 106
            +   SS G   S SGYS  +G +E+  + S     Y   G      S   Q G      
Sbjct: 445 GFGRSSSSGPYVSGSGYSSGFGHHESSSEHSSG---YTQHGSGSGHSSGHGQHGSRSGQS 501

Query: 107 QPDYGQQDSYDQQSGYDQHQGSYDEQSNYDQQHDSYS--------QNQQSYHSQRENYSH 158
                Q  S    S Y QH GS   QS    +H S S           +S   Q  +Y  
Sbjct: 502 SRGERQGSSAGSSSSYGQH-GSGSRQSLGHSRHGSGSGQSPSPSRGRHESGSRQSSSYGP 560

Query: 159 HTQDDRRDVSRYGEDNRGYGGSQG-----------GGRGRGGYDKDGRGPMTGSSGGDRG 207
           H     R  SR G    G G S G            G G+ G    G     G  G   G
Sbjct: 561 HGYGSGRSSSR-GPYESGSGHSSGLGHQESRSGQSSGYGQHG-SSSGHSSTHGQHGSTSG 618

Query: 208 GFKNFGGHRDYGPRTDADSE--SDNSDNNTIFVQGLGEGVSTDQVGEFFKQIGIIKTNKK 265
              + G H     ++ +  +  S +S ++    QG G G S  + G      G   +  +
Sbjct: 619 QSSSCGQHGATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSR-GRHGSDFGHSSSYGQ 677

Query: 266 TGKPMINLYTDKDTGKPKGEATVSFDDPPSAKAA--------IDWFDGKEFHGNIIKVSF 317
            G       ++   G   G+++       S +++             G   HG+    S 
Sbjct: 678 HGSGSGWSSSNGPHGSVSGQSSGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSS 737

Query: 318 ATRRPEFMRGGGSGGGRRGRGGYRGRG-GFQGRGGDPKSGDWVCPNPSCGNMNFARRNSC 376
            + +     G  S  G+ G G ++  G G QG G           + S  + +  +  S 
Sbjct: 738 RSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQHGSG 797

Query: 377 NQCNEPRPEDSRPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGG 436
             C+         SG   +  G+G      G+        GY    S  G+   +   G 
Sbjct: 798 TSCSSSCGHYESGSG---QASGFGQHESGSGQ--------GYSQHGSASGHFSSQGRHGS 846

Query: 437 YSGDRSGGGYGGDRSG--GGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGY 494
            SG  S  G     SG    YG      +     G +G   G   G  + G G  +   Y
Sbjct: 847 TSGQSSSSGQHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGSGSGQSPSY 906

Query: 495 GGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRS 554
           G  R G G  R    G  G   G   G+G   S G   G    GSG G   S    G RS
Sbjct: 907 G--RHGSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRS 964

Query: 555 GGGYGGDRGGGYGGDRGGYG 574
           G     ++ G   G    YG
Sbjct: 965 GQSSRSEQHGSSSGSSSSYG 984



 Score =  103 bits (256), Expect = 6e-22
 Identities = 144/609 (23%), Positives = 190/609 (31%), Gaps = 60/609 (9%)

Query: 5    GSYGQSGGEQQSYSTYGNPGSQGYGQASQ-SYSGYGQTTDSSYGQNYSGYSSYGQSQSGY 63
            G +    G   +YS +G+       Q    S SG   T D   G +    SSYG   SG 
Sbjct: 1285 GQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQE-GSSTGQSSSYGHRGSGS 1343

Query: 64   SQSYGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQQSGYD 123
            SQS  GY      S         G      SS  Q G    +            Q SG+ 
Sbjct: 1344 SQS-SGYGRHGAGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFG 1402

Query: 124  QHQGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRR-----DVSRYGEDNRGYG 178
             H+ S   QS+   QH S S +  SY          ++ +R        S YG+   G G
Sbjct: 1403 HHESS-SWQSSGCTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQ--HGSG 1459

Query: 179  GSQGGGRGRGGYDKDGRGPMTGSSGGDRG-GFKNFGGHRDYGPRTDADSESDNSDNNTIF 237
              Q  G G+ G    G G     S G  G G      +  YG  +   S     ++ +  
Sbjct: 1460 SRQSLGHGQHG---SGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSSH 1516

Query: 238  VQGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATVSFDDPPSAK 297
              GLG   S       + Q G    +           T    G   G+++       S+ 
Sbjct: 1517 SSGLGHRESRSGQSSGYGQHGSSSGHSS---------THGQHGSTSGQSSSCGQHGASSG 1567

Query: 298  AAIDWFDGKEFHGNIIKVSFATRRPEFMRGGGSGGGRRGRGGYRGRG-GFQGRGGDPKSG 356
             +         HG+    S    R     G   G G+RG G  +    G  G G    S 
Sbjct: 1568 QS----SSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSS 1623

Query: 357  DWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGRGGRGGDRG 416
                 +    +  F    S +  +    +    SG       +G   G   RG R G   
Sbjct: 1624 SGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSS 1683

Query: 417  GYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYG-----GDRGGGYGGDRGGGY 471
                     G G  +SSG G  G  SG      R G G G     G  G G G     G 
Sbjct: 1684 RSSSRYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGP 1743

Query: 472  GGDRGGG---YGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRG------------GYG 516
               R G    +G    G G        G   G+   +G +G   G            G  
Sbjct: 1744 YESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQS 1803

Query: 517  GDRGGYGGDRSRGGYGGDRGGGSGY---------GGDRSGGYGGDRSGGGYGGDRG--GG 565
               G +G   S+    G +G GSG          G   S  YG   SG G+    G  G 
Sbjct: 1804 SSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGS 1863

Query: 566  YGGDRGGYG 574
              G   G+G
Sbjct: 1864 GSGQSSGFG 1872



 Score = 83.2 bits (204), Expect = 6e-16
 Identities = 129/522 (24%), Positives = 178/522 (34%), Gaps = 61/522 (11%)

Query: 85  NQGQQQNMESSGSQGGRAPS---YDQPDYGQQDSYDQ------QSGYDQHQGSYDEQSNY 135
           +Q Q++  E+   +  R  S   +     G+ DSY +      + G +        Q ++
Sbjct: 106 HQHQEEQEETEKEENKRQESSFSHSSWSAGENDSYSRNVRGSLKPGTESISRRLSFQRDF 165

Query: 136 DQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSRYGED-NRGYGGSQGGGRGRGGYDKDG 194
             QH+SYS    SY  Q  + SH +    +  S  G+  N G  GS  G          G
Sbjct: 166 SGQHNSYSGQSSSYGEQNSD-SHQSSGRGQCGSGSGQSPNYGQHGSGSGQSSSNDTHGSG 224

Query: 195 RGPMTG-----SSGGDRGGFKNFG---GHRD-YGPRTDADSESDNSDNNTIFVQGLGEGV 245
            G  +G     SS G   G+   G   GH   YG       +S   + +       G   
Sbjct: 225 SGQSSGFSQHKSSSGQSSGYSQHGSGSGHSSGYGQHGSRSGQSSRGERHR---SSSGSSS 281

Query: 246 STDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATVSFDDPPSAKAAIDWFDG 305
           S  Q G   +Q  +    + +G    +  +        G    S      + ++  +  G
Sbjct: 282 SYGQHGSGSRQ-SLGHGRQGSG----SRQSPSHVRHGSGSGHSSSHGQHGSGSSYSYSRG 336

Query: 306 KEFHGNIIKVSFATRRPEFMRGGGSGGGRRGRGGYRGRGGFQGRGGDPKSGDWVCPNPSC 365
               G+     F     +   G G   G    G   G    QG+ G   SG     + S 
Sbjct: 337 HYESGSGQTSGFG----QHESGSGQSSGYSKHGSGSGHSSSQGQHGS-TSGQ---ASSSG 388

Query: 366 GNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRSGG 425
            + + +R++S    +E     S   G    G G     G RG G       G    + G 
Sbjct: 389 QHGSSSRQSSSYGQHESASRHSSGRGQHSSGSGQSPGHGQRGSGSGQSPSSG----QHGT 444

Query: 426 GYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGG 485
           G+G   SSG   SG     G+G   S      +   GY    G G G   G G  G R G
Sbjct: 445 GFGRSSSSGPYVSGSGYSSGFGHHES----SSEHSSGY-TQHGSGSGHSSGHGQHGSRSG 499

Query: 486 YG--GDRGGGYGGDRGGYG----GDRGGYGGDRGGYGGDRGGYGGDRSRGGY-GGDRGGG 538
               G+R G   G    YG    G R   G  R G G    G     SRG +  G R   
Sbjct: 500 QSSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSG---SGQSPSPSRGRHESGSRQSS 556

Query: 539 S----GYGGDRSGGYGGDRSGGGYGGDRG--GGYGGDRGGYG 574
           S    GYG  RS   G   SG G+    G      G   GYG
Sbjct: 557 SYGPHGYGSGRSSSRGPYESGSGHSSGLGHQESRSGQSSGYG 598



 Score = 67.4 bits (163), Expect = 4e-11
 Identities = 118/507 (23%), Positives = 154/507 (30%), Gaps = 66/507 (13%)

Query: 122 YDQHQGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSRYGEDNRGY--GG 179
           Y Q  GS      +  Q +     ++    Q  ++SH +     + S Y  + RG    G
Sbjct: 93  YCQVSGSKLRDDTHQHQEEQEETEKEENKRQESSFSHSSWSAGENDS-YSRNVRGSLKPG 151

Query: 180 SQGGGRGRGGYDKDGRGPMTGSSGGDRG-GFKNFGGHRDYGPRTDADSESDNSDNNTIFV 238
           ++   R R  + +D  G     SG     G +N   H+  G R    S S  S N     
Sbjct: 152 TESISR-RLSFQRDFSGQHNSYSGQSSSYGEQNSDSHQSSG-RGQCGSGSGQSPNYGQHG 209

Query: 239 QGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATVSFDDPPSAKA 298
            G G+  S D  G    Q      +K +            +G+  G +        S+  
Sbjct: 210 SGSGQSSSNDTHGSGSGQSSGFSQHKSS------------SGQSSGYSQHGSGSGHSS-- 255

Query: 299 AIDWFDGKEFHGNIIKVSFATRRPEFMRGGGSGGGRRGRGGYRGRG-GFQGRGGDPKSGD 357
                 G   HG+    S    R     G  S  G+ G G  +  G G QG G       
Sbjct: 256 ------GYGQHGSRSGQSSRGERHRSSSGSSSSYGQHGSGSRQSLGHGRQGSGSRQSPSH 309

Query: 358 WVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSG----------GDFRGRGYGGERGYRG 407
               + S  + +  +  S +  +  R      SG          G  +  GY       G
Sbjct: 310 VRHGSGSGHSSSHGQHGSGSSYSYSRGHYESGSGQTSGFGQHESGSGQSSGYSKHGSGSG 369

Query: 408 RGGRGGDRGGYGGDRSGGGYGGDRSS-----GGGYSGDRSGGGYGGDRSGGGYG---GDR 459
                G  G   G  S  G  G  S      G   S  R   G G   SG G     G R
Sbjct: 370 HSSSQGQHGSTSGQASSSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGSGQSPGHGQR 429

Query: 460 GGGYG-----GDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGG 514
           G G G     G  G G+G     G      GY    G          G  + G G     
Sbjct: 430 GSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYSSGFGHHESSSEHSSGYTQHGSGSGHSS 489

Query: 515 YGGDRGGYGGDRSRG-GYGGDRGGGSGYGGDRSG---GYGGDRSGGGYG----------- 559
             G  G   G  SRG   G   G  S YG   SG     G  R G G G           
Sbjct: 490 GHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSPSPSRGRHE 549

Query: 560 -GDRGGGYGGDRGGYGGKMGGRNDYRN 585
            G R     G  G   G+   R  Y +
Sbjct: 550 SGSRQSSSYGPHGYGSGRSSSRGPYES 576



 Score = 64.7 bits (156), Expect = 2e-10
 Identities = 70/216 (32%), Positives = 92/216 (42%), Gaps = 36/216 (16%)

Query: 2    SDSGS---YGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSG---YSS 55
            S SGS   YGQ G   +  S +G  GS      S+   G G    SS+GQ+ SG    SS
Sbjct: 2621 SSSGSSSHYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSS 2680

Query: 56   YG--QSQSGYSQSYGGYENQK--QSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQ--PD 109
             G  +S+ G+S  +G +E+     S+YSQ   +  G   +    GS  G++ ++DQ    
Sbjct: 2681 RGPYESRLGHSSVFGQHESGSGHSSAYSQHG-SGSGHFCSQGQHGSTSGQSSTFDQEGSS 2739

Query: 110  YGQQDSY-------DQQSGYDQHQGSYDEQSNYDQQHDSYSQNQQSY------HSQRENY 156
             GQ  SY        Q SGY +H G+   QS    +H S S    SY        Q   Y
Sbjct: 2740 TGQSSSYGHRGSGSSQSSGYGRH-GAGSGQSLSHGRHGSGSGQSSSYGQHGSGSGQSSGY 2798

Query: 157  SHHTQDDRRDVSRYGEDNRGY--GGSQGGGRGRGGY 190
            S H        S  G+D   Y  GGS   G   G Y
Sbjct: 2799 SQHG-------SGSGQDGYSYCKGGSNHDGGSSGSY 2827



 Score = 63.9 bits (154), Expect = 4e-10
 Identities = 76/256 (29%), Positives = 101/256 (39%), Gaps = 35/256 (13%)

Query: 2    SDSGSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQN--YSGYSSYGQ- 58
            S SG +G   GE    S +G+  S     +S S  G G    S YGQ+   SG SS G+ 
Sbjct: 2562 SSSGQHGSGLGES---SGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGER 2618

Query: 59   --SQSGYSQSYGGY-ENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDS 115
              S SG S  YG +    +QSS   +  +  GQ  +    GS  G + S+ Q   G   S
Sbjct: 2619 HGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRS 2678

Query: 116  -----YDQQSGYD----QHQGSYDEQSNYDQQHDS-----YSQNQQSYHSQRENYSHHTQ 161
                 Y+ + G+     QH+      S Y  QH S      SQ Q    S + +      
Sbjct: 2679 SSRGPYESRLGHSSVFGQHESGSGHSSAY-SQHGSGSGHFCSQGQHGSTSGQSSTFDQEG 2737

Query: 162  DDRRDVSRYGEDNRGYGGSQGGGRGRGG--------YDKDGRGPMTGSSGGDRG-GFKNF 212
                  S YG  +RG G SQ  G GR G        + + G G    SS G  G G    
Sbjct: 2738 SSTGQSSSYG--HRGSGSSQSSGYGRHGAGSGQSLSHGRHGSGSGQSSSYGQHGSGSGQS 2795

Query: 213  GGHRDYGPRTDADSES 228
             G+  +G  +  D  S
Sbjct: 2796 SGYSQHGSGSGQDGYS 2811



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 36/114 (31%), Positives = 49/114 (42%), Gaps = 4/114 (3%)

Query: 4    SGSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGY---SSYGQSQ 60
            S ++ Q G      S+YG+ GS     +     G G     S+G++ SG    SSYGQ  
Sbjct: 2730 SSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSLSHGRHGSGSGQSSSYGQHG 2789

Query: 61   SGYSQSYGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQP-DYGQQ 113
            SG  QS G  ++   S      Y   G   +  SSGS     PS   P +Y Q+
Sbjct: 2790 SGSGQSSGYSQHGSGSGQDGYSYCKGGSNHDGGSSGSYFLSFPSSTSPYEYVQE 2843


>gi|62122917 filaggrin family member 2 [Homo sapiens]
          Length = 2391

 Score =  132 bits (333), Expect = 7e-31
 Identities = 166/615 (26%), Positives = 230/615 (37%), Gaps = 58/615 (9%)

Query: 2    SDSGSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQSQS 61
            S  G +G   G+   +  YG+   Q  G   Q  SG GQ++     ++ SG SSYGQ  S
Sbjct: 565  SGFGQHGLGSGQSTGFGQYGSGSGQSSG-FGQHGSGSGQSSGFGQHESRSGQSSYGQHSS 623

Query: 62   GYSQSYG-GYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQ--------PDYGQ 112
            G SQS G G    +Q+S   Q  +   Q       GS  G++  + Q          +GQ
Sbjct: 624  GSSQSSGYGQHGSRQTSGFGQHGSGSSQSTGFGQYGSGSGQSSGFGQHVSGSGQSSGFGQ 683

Query: 113  QDSYDQQSGYDQHQGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSRYGE 172
             +S    S Y QH     + S Y Q H S S  Q S   Q E  S  +       S +G+
Sbjct: 684  HESRSGHSSYGQHGFGSSQSSGYGQ-HGS-SSGQTSGFGQHELSSGQS-------SSFGQ 734

Query: 173  DNRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDADSESDN-S 231
               G G S G G+   G         +G S G  G  ++  G   YG  +   S+S    
Sbjct: 735  HGSGSGQSSGFGQHGSG---------SGQSSGF-GQHESRSGQSSYGQHSSGSSQSSGYG 784

Query: 232  DNNTIFVQGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATVSFD 291
             + +    G G+  S       F Q G   + +  G       + + +G  + E+     
Sbjct: 785  QHGSRQTSGFGQHGSGSSQSTGFGQYGS-GSGQSAGFGQHGSGSGQSSGFGQHESRSHQS 843

Query: 292  DPPSAKAAIDWFDGKEFHGNIIKVSFATRRPEFMRGGGSGGGRRGRGGYRGRG-GFQGRG 350
                  +      G   HG+    +    +     G  SG G+ G G  +  G G  G G
Sbjct: 844  SYGQHGSGSSQSSGYGQHGSSSGQTSGFGQHRSSSGQYSGFGQHGSGSGQSSGFGQHGTG 903

Query: 351  GDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGRGG 410
                SG     + S    ++ +  S +  +    +    SG  F   G+G  R   G+  
Sbjct: 904  SGQYSGFGQHESRS-HQSSYGQHGSGSSQSSGYGQHGSSSGQTF---GFGQHRSGSGQSS 959

Query: 411  RGGDRGGYGGDRSGGGY---GGDRSSGGGYSGDRSG-GGYGGDRSGG----GYGGDRGGG 462
              G  G   G  SG G    G  +SSG G    RS    YG   SG     GYG   G  
Sbjct: 960  GFGQHGSGSGQSSGFGQHESGSGKSSGFGQHESRSSQSNYGQHGSGSSQSSGYG-QHGSS 1018

Query: 463  YGGDRGGGYGGDRGGGYGG-DRGGYGGDRGGGYGGDRGGYGGDRGGYG-----GDRGGYG 516
             G   G G      G Y G  + G G D+  G+G   G   G   G+G       +  YG
Sbjct: 1019 SGQTTGFGQHRSSSGQYSGFGQHGSGSDQSSGFG-QHGTGSGQSSGFGQYESRSRQSSYG 1077

Query: 517  GDRGGYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSG-GGYGGDRGGGYG-GDRGGYG 574
                G       G +G + G  SG+G  R G   G  SG G YG   G   G G  G   
Sbjct: 1078 QHGSGSSQSSGYGQHGSNSGQTSGFGQHRPG--SGQSSGFGQYGSGSGQSSGFGQHGSGT 1135

Query: 575  GKMGG--RNDYRNDQ 587
            GK  G  +++YR+ Q
Sbjct: 1136 GKSSGFAQHEYRSGQ 1150



 Score =  132 bits (331), Expect = 1e-30
 Identities = 173/637 (27%), Positives = 232/637 (36%), Gaps = 67/637 (10%)

Query: 2    SDSGSYGQSGGEQQSYSTYGNPGSQGYGQAS---QSYSGYGQTTDSSYGQ--NYSGYSS- 55
            S S  Y Q G      S +G  GS G GQ+S   Q  SG GQ+  S +GQ  + SG SS 
Sbjct: 461  SQSLGYDQHGSSSGKTSGFGQHGS-GSGQSSGFGQCGSGSGQS--SGFGQHGSVSGQSSG 517

Query: 56   YGQ--SQSGYSQSYGGYENQ-KQSSYSQ-----QPYNNQGQQQNMESSGSQGGRAPSYDQ 107
            +GQ  S SG S  +G +E++ +QSSY Q        +  GQ  + E+SG       S   
Sbjct: 518  FGQHGSVSGQSSGFGQHESRSRQSSYGQHGSGSSQSSGYGQYGSRETSGFGQHGLGSGQS 577

Query: 108  PDYGQQDS-YDQQSGYDQHQGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSH-HTQDDRR 165
              +GQ  S   Q SG+ QH     + S + Q      Q+    HS   + S  + Q   R
Sbjct: 578  TGFGQYGSGSGQSSGFGQHGSGSGQSSGFGQHESRSGQSSYGQHSSGSSQSSGYGQHGSR 637

Query: 166  DVSRYGEDNRGYGGSQGGGR-GRGGYDKDGRGPMTGSSGGDR--GGFKNFGGHRDYGPRT 222
              S +G+   G   S G G+ G G     G G     SG     G  ++  GH  YG   
Sbjct: 638  QTSGFGQHGSGSSQSTGFGQYGSGSGQSSGFGQHVSGSGQSSGFGQHESRSGHSSYGQHG 697

Query: 223  DADSESD---NSDNNTIFVQGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDT 279
               S+S       +++    G G+   +      F Q G   + + +G       + + +
Sbjct: 698  FGSSQSSGYGQHGSSSGQTSGFGQHELSSGQSSSFGQHG-SGSGQSSGFGQHGSGSGQSS 756

Query: 280  GKPKGEATVSFDDPPSAKAAIDWFDGKEFHGNIIKVSFATRRPEFMRGGGSGGGRRGRGG 339
            G  + E+           +      G   HG        +R+       GSG  +    G
Sbjct: 757  GFGQHESRSGQSSYGQHSSGSSQSSGYGQHG--------SRQTSGFGQHGSGSSQSTGFG 808

Query: 340  YRGRGGFQGRG-GDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRG 398
              G G  Q  G G   SG       S G      R+  +   +     S+ SG    G  
Sbjct: 809  QYGSGSGQSAGFGQHGSGS----GQSSGFGQHESRSHQSSYGQHGSGSSQSSGYGQHGSS 864

Query: 399  YGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGD 458
             G   G+       G   G+G   SG G        G  SG  SG G    RS     G 
Sbjct: 865  SGQTSGFGQHRSSSGQYSGFGQHGSGSGQSSGFGQHGTGSGQYSGFGQHESRSHQSSYGQ 924

Query: 459  RGGGYGGDRGGGYGGDRGG---GYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGY 515
             G G     G G  G   G   G+G  R G G   G    G  G   G   G+G    G 
Sbjct: 925  HGSGSSQSSGYGQHGSSSGQTFGFGQHRSGSGQSSG---FGQHGSGSGQSSGFGQHESG- 980

Query: 516  GGDRGGYGGDRSR------GGYGGDRGGGSGYG--GDRSG---GYGGDRSGGGY------ 558
             G   G+G   SR      G +G      SGYG  G  SG   G+G  RS  G       
Sbjct: 981  SGKSSGFGQHESRSSQSNYGQHGSGSSQSSGYGQHGSSSGQTTGFGQHRSSSGQYSGFGQ 1040

Query: 559  ---GGDRGGGYGGDRGGYGGKMGGRNDYRNDQRNRPY 592
               G D+  G+ G  G   G+  G   Y +  R   Y
Sbjct: 1041 HGSGSDQSSGF-GQHGTGSGQSSGFGQYESRSRQSSY 1076



 Score =  127 bits (319), Expect = 3e-29
 Identities = 170/656 (25%), Positives = 239/656 (36%), Gaps = 95/656 (14%)

Query: 5   GSYGQSGGEQQSY-STYGNPGSQGYGQASQSYSGYGQTTDSS----------YGQNYSGY 53
           G   ++G  Q S    YG+ GSQ        Y   G+ ++SS          YG   S  
Sbjct: 367 GGQWRTGSSQSSCCGQYGSGGSQSCSNGQHEYGSCGRFSNSSSSNEFSKCDQYGSGSSQS 426

Query: 54  SSYGQSQSGYSQSYGGYEN---------QKQSSYSQ-----QPYNNQGQQQNMESSGSQG 99
           +S+ Q  +G SQS G  ++         Q +S+ SQ     Q  ++ G+       GS  
Sbjct: 427 TSFEQHGTGLSQSSGFEQHVCGSGQTCGQHESTSSQSLGYDQHGSSSGKTSGFGQHGSGS 486

Query: 100 GRAPSYDQ--------PDYGQQDSYD-QQSGYDQHQGSYDEQSNYDQQHDSYSQNQQSY- 149
           G++  + Q          +GQ  S   Q SG+ QH GS   QS+   QH+S S+ Q SY 
Sbjct: 487 GQSSGFGQCGSGSGQSSGFGQHGSVSGQSSGFGQH-GSVSGQSSGFGQHESRSR-QSSYG 544

Query: 150 --HSQRENYSHHTQDDRRDVSRYGEDNRGYGGSQGGGR-GRGGYDKDGRGPMTGSSGGDR 206
              S     S + Q   R+ S +G+   G G S G G+ G G     G G   GS  G  
Sbjct: 545 QHGSGSSQSSGYGQYGSRETSGFGQHGLGSGQSTGFGQYGSGSGQSSGFG-QHGSGSGQS 603

Query: 207 GGF---KNFGGHRDYGPRTDADSESDN-SDNNTIFVQGLGEGVSTDQVGEFFKQIGIIKT 262
            GF   ++  G   YG  +   S+S     + +    G G+  S       F Q G   +
Sbjct: 604 SGFGQHESRSGQSSYGQHSSGSSQSSGYGQHGSRQTSGFGQHGSGSSQSTGFGQYG-SGS 662

Query: 263 NKKTGKPMINLYTDKDTGKPKGEATVSFDDPPSAKAAIDWFDGKEFHGNIIKVSFATRRP 322
            + +G       + + +G  + E+                  G   HG+    +    + 
Sbjct: 663 GQSSGFGQHVSGSGQSSGFGQHESRSGHSSYGQHGFGSSQSSGYGQHGSSSGQTSGFGQH 722

Query: 323 EFMRGGGSGGGRRGRGGYRGRGGFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEP 382
           E   G  S  G+ G G  +  G  Q   G  +S  +       G  ++ + +S       
Sbjct: 723 ELSSGQSSSFGQHGSGSGQSSGFGQHGSGSGQSSGFGQHESRSGQSSYGQHSS------- 775

Query: 383 RPEDSRPSGGDFRGRGYG--GER---GYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGY 437
                    G  +  GYG  G R   G+   G       G+G   SG G        G  
Sbjct: 776 ---------GSSQSSGYGQHGSRQTSGFGQHGSGSSQSTGFGQYGSGSGQSAGFGQHGSG 826

Query: 438 SGDRSGGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGG---GYGGDRGGYGGDRGGGY 494
           SG  SG G    RS     G  G G     G G  G   G   G+G  R   G   G G 
Sbjct: 827 SGQSSGFGQHESRSHQSSYGQHGSGSSQSSGYGQHGSSSGQTSGFGQHRSSSGQYSGFGQ 886

Query: 495 GGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSR------GGYGGDRGGGSGYG--GDRS 546
            G   G     G +G   G Y     G+G   SR      G +G      SGYG  G  S
Sbjct: 887 HGSGSGQSSGFGQHGTGSGQY----SGFGQHESRSHQSSYGQHGSGSSQSSGYGQHGSSS 942

Query: 547 G---GYGGDRSGGGY---------GGDRGGGYGGDRGGYGGKMG-GRNDYRNDQRN 589
           G   G+G  RSG G          G  +  G+G    G G   G G+++ R+ Q N
Sbjct: 943 GQTFGFGQHRSGSGQSSGFGQHGSGSGQSSGFGQHESGSGKSSGFGQHESRSSQSN 998



 Score =  123 bits (309), Expect = 4e-28
 Identities = 172/657 (26%), Positives = 226/657 (34%), Gaps = 101/657 (15%)

Query: 2    SDSGSYGQSGGEQQSYSTYGNPGSQ--GYGQ---ASQSYSGYGQT-----TDSSYGQNYS 51
            S  G +G   G+   +   G+   Q  G+GQ    S   SG+GQ        S +GQ+ S
Sbjct: 477  SGFGQHGSGSGQSSGFGQCGSGSGQSSGFGQHGSVSGQSSGFGQHGSVSGQSSGFGQHES 536

Query: 52   G--YSSYGQSQSGYSQS--YGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQ 107
                SSYGQ  SG SQS  YG Y +++ S + Q    + GQ       GS  G++  + Q
Sbjct: 537  RSRQSSYGQHGSGSSQSSGYGQYGSRETSGFGQHGLGS-GQSTGFGQYGSGSGQSSGFGQ 595

Query: 108  --------PDYGQQDSYDQQSGYDQHQGSYDEQSNYDQ----------QHDSYSQNQQSY 149
                      +GQ +S   QS Y QH     + S Y Q          QH S S     +
Sbjct: 596  HGSGSGQSSGFGQHESRSGQSSYGQHSSGSSQSSGYGQHGSRQTSGFGQHGSGSSQSTGF 655

Query: 150  ------HSQRENYSHHTQDDRRDVSRYGEDNRGYGGSQGGGRGRGGYDKDGRGPMTGSSG 203
                    Q   +  H     +  S +G+     G S  G  G G     G G   GSS 
Sbjct: 656  GQYGSGSGQSSGFGQHVSGSGQS-SGFGQHESRSGHSSYGQHGFGSSQSSGYG-QHGSSS 713

Query: 204  GDRGGFKNFGGHR-DYGPRTDADSESDNSDNNTIFVQ-GLGEGVSTDQVGEFFKQIGIIK 261
            G   GF   G H    G  +        S  ++ F Q G G G S+      F Q     
Sbjct: 714  GQTSGF---GQHELSSGQSSSFGQHGSGSGQSSGFGQHGSGSGQSSG-----FGQHESRS 765

Query: 262  TNKKTGKPMINLYTDKDTGKPKGEATVSFDDPPSAKAAIDWFDGKEFHGNIIKVSFATRR 321
                 G+           G+     T  F    S  +    F G+   G+     F    
Sbjct: 766  GQSSYGQHSSGSSQSSGYGQHGSRQTSGFGQHGSGSSQSTGF-GQYGSGSGQSAGFGQHG 824

Query: 322  PEFMRGGGSGGGRRGRGGYRGRGGFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNE 381
                 G  SG G+     ++   G  G G    SG     + S     F +  S +    
Sbjct: 825  SG--SGQSSGFGQHESRSHQSSYGQHGSGSSQSSGYGQHGSSSGQTSGFGQHRSSS---- 878

Query: 382  PRPEDSRPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRSGG--------GYGGDRSS 433
                  + SG    G G G   G+   G   G   G+G   S          G G  +SS
Sbjct: 879  -----GQYSGFGQHGSGSGQSSGFGQHGTGSGQYSGFGQHESRSHQSSYGQHGSGSSQSS 933

Query: 434  GGGYSGDRSGG--GYGGDRSGGGYG---GDRGGGYGGDRGGGY---GGDRGGGYG----- 480
            G G  G  SG   G+G  RSG G     G  G G G   G G    G  +  G+G     
Sbjct: 934  GYGQHGSSSGQTFGFGQHRSGSGQSSGFGQHGSGSGQSSGFGQHESGSGKSSGFGQHESR 993

Query: 481  GDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRG--GYGGDRGGG 538
              +  YG  + G       GYG   G   G   G+G  R   G     G  G G D+  G
Sbjct: 994  SSQSNYG--QHGSGSSQSSGYG-QHGSSSGQTTGFGQHRSSSGQYSGFGQHGSGSDQSSG 1050

Query: 539  SGYGGDRSG---GYGGDRSGG--------GYGGDRGGGYGGDRGGYGGKMGGRNDYR 584
             G  G  SG   G+G   S          G G  +  GY G  G   G+  G   +R
Sbjct: 1051 FGQHGTGSGQSSGFGQYESRSRQSSYGQHGSGSSQSSGY-GQHGSNSGQTSGFGQHR 1106



 Score =  119 bits (299), Expect = 6e-27
 Identities = 164/619 (26%), Positives = 225/619 (36%), Gaps = 84/619 (13%)

Query: 2    SDSGSYGQSGGEQQS-YSTYGNPGSQG-----YGQASQSYSGYGQTTDSS-----YGQNY 50
            S S  YGQ G  Q S +  +G+  SQ      YG  S   SG+GQ    S     +GQ+ 
Sbjct: 626  SQSSGYGQHGSRQTSGFGQHGSGSSQSTGFGQYGSGSGQSSGFGQHVSGSGQSSGFGQHE 685

Query: 51   S--GYSSYGQSQSGYSQSYG----GYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPS 104
            S  G+SSYGQ   G SQS G    G  + + S + Q   ++ GQ  +    GS  G++  
Sbjct: 686  SRSGHSSYGQHGFGSSQSSGYGQHGSSSGQTSGFGQHELSS-GQSSSFGQHGSGSGQSSG 744

Query: 105  YDQPDYGQQDSYDQQSGYDQHQGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDR 164
            + Q   G      Q SG+ QH+ S   QS+Y Q H S S       SQ   Y  H     
Sbjct: 745  FGQHGSGS----GQSSGFGQHE-SRSGQSSYGQ-HSSGS-------SQSSGYGQHGS--- 788

Query: 165  RDVSRYGEDNRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRD------Y 218
            R  S +G+   G G SQ  G G+ G    G+    G  G   G    FG H        Y
Sbjct: 789  RQTSGFGQ--HGSGSSQSTGFGQYG-SGSGQSAGFGQHGSGSGQSSGFGQHESRSHQSSY 845

Query: 219  GPRTDADSESDN-SDNNTIFVQGLGEGVSTDQVGEF--FKQIGIIKTNKKTGKPMINLYT 275
            G      S+S     + +   Q  G G      G++  F Q G   + + +G       +
Sbjct: 846  GQHGSGSSQSSGYGQHGSSSGQTSGFGQHRSSSGQYSGFGQHGS-GSGQSSGFGQHGTGS 904

Query: 276  DKDTGKPKGEATVSFDDPPSAKAAIDWFDGKEFHGNIIKVSFATRRPEFMRGGGSGGGRR 335
             + +G  + E+           +      G   HG+    +F   +     G  SG G+ 
Sbjct: 905  GQYSGFGQHESRSHQSSYGQHGSGSSQSSGYGQHGSSSGQTFGFGQHRSGSGQSSGFGQH 964

Query: 336  GRGGYRGRGGFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSG---G 392
            G G  +  G  Q   G  KS  +          N+ +  S +  +    +    SG   G
Sbjct: 965  GSGSGQSSGFGQHESGSGKSSGFGQHESRSSQSNYGQHGSGSSQSSGYGQHGSSSGQTTG 1024

Query: 393  DFRGRGYGGERGYRGRGGRGGDRG------GYGGDRSGG----------------GYGGD 430
              + R   G+    G+ G G D+       G G  +S G                G G  
Sbjct: 1025 FGQHRSSSGQYSGFGQHGSGSDQSSGFGQHGTGSGQSSGFGQYESRSRQSSYGQHGSGSS 1084

Query: 431  RSSGGGYSGDRSG--GGYGGDRSGGGYG---GDRGGGYG-----GDRGGGYGGDRGGGYG 480
            +SSG G  G  SG   G+G  R G G     G  G G G     G  G G G   G    
Sbjct: 1085 QSSGYGQHGSNSGQTSGFGQHRPGSGQSSGFGQYGSGSGQSSGFGQHGSGTGKSSGFAQH 1144

Query: 481  GDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSG 540
              R G       G G  +    G      G    +G    G     S G +  D G  +G
Sbjct: 1145 EYRSGQSSYGQHGTGSSQSSGCGQHESGSGPTTSFGQHVSGSDNFSSSGQHISDSGQSTG 1204

Query: 541  YGGDRSGGYGGDRSGGGYG 559
            +G   SG   G  +G G G
Sbjct: 1205 FGQYGSG--SGQSTGLGQG 1221



 Score = 83.2 bits (204), Expect = 6e-16
 Identities = 165/650 (25%), Positives = 223/650 (34%), Gaps = 127/650 (19%)

Query: 2    SDSGSYGQSGGEQQSYSTYGNPGSQGYGQA---SQSYSGYGQTTDSSYGQNYSGY---SS 55
            S   SYGQ G      S YG  GS   GQ     Q  SG GQ+  S +GQ+ SG    S 
Sbjct: 917  SHQSSYGQHGSGSSQSSGYGQHGSSS-GQTFGFGQHRSGSGQS--SGFGQHGSGSGQSSG 973

Query: 56   YGQSQSGYSQSYGGYENQKQSSYSQQPYNNQGQQQNM------ESSGSQGG----RAPSY 105
            +GQ +SG  +S G  +++ +SS S    +  G  Q+        SSG   G    R+ S 
Sbjct: 974  FGQHESGSGKSSGFGQHESRSSQSNYGQHGSGSSQSSGYGQHGSSSGQTTGFGQHRSSSG 1033

Query: 106  DQPDYGQQDS-YDQQSGYDQHQGSYDEQSNYDQQHDSYSQNQQSYH----SQRENYSHHT 160
                +GQ  S  DQ SG+ QH     + S + Q      Q+    H    SQ   Y  H 
Sbjct: 1034 QYSGFGQHGSGSDQSSGFGQHGTGSGQSSGFGQYESRSRQSSYGQHGSGSSQSSGYGQHG 1093

Query: 161  QDDRRDVSRYGEDNRGYGGSQGGGR-GRGGYDKDG---RGPMTGSSGGD-----RGGFKN 211
             +  +  S +G+   G G S G G+ G G     G    G  TG S G      R G  +
Sbjct: 1094 SNSGQ-TSGFGQHRPGSGQSSGFGQYGSGSGQSSGFGQHGSGTGKSSGFAQHEYRSGQSS 1152

Query: 212  FGGH--------------RDYGPRTDADSESDNSDN-------------NTIFVQ-GLGE 243
            +G H                 GP T        SDN             +T F Q G G 
Sbjct: 1153 YGQHGTGSSQSSGCGQHESGSGPTTSFGQHVSGSDNFSSSGQHISDSGQSTGFGQYGSGS 1212

Query: 244  GVSTDQVGEFFKQIGIIKT----NKKTGKPMINLYTDKDTGKPKGEAT-----------V 288
            G ST       +Q+    T     + T    IN      +G+ +   T            
Sbjct: 1213 GQSTGLGQGESQQVESGSTVHGRQETTHGQTINTTRHSQSGQGQSTQTGSRVTRRRRSSQ 1272

Query: 289  SFDDPPSAKAAIDWFDGKEFH----------GNIIKVSFAT---RRPEFMRGGGSGGGRR 335
            S +      + +     +  H          G+ ++    T   +R +  R G SG G+ 
Sbjct: 1273 SENSDSEVHSKVSHRHSEHIHTQAGSHYPKSGSTVRRRQGTTHGQRGDTTRHGHSGHGQS 1332

Query: 336  GRGGYR--GRGGFQGRGG-DPKSGDWVCPNPSCGNMNFARRNSCNQCNEP----RPEDSR 388
             + G R  GR  F      D +    V   P       ++  S +  +E     R E + 
Sbjct: 1333 TQTGSRTSGRQRFSHSDATDSEVHSGVSHRPHSQEQTHSQAGSQHGESESTVHERHETTY 1392

Query: 389  PSGGDFRGRGYGG-----ERGYR--GRGGRGGDRGGYGGDRSGGGY--------GGDRSS 433
               G+  G G+ G     +RG R  GR G G          SGG +         G   S
Sbjct: 1393 GQTGEATGHGHSGHGQSTQRGSRTTGRRGSGHSESSDSEVHSGGSHRPQSQEQTHGQAGS 1452

Query: 434  GGGYSGDRSGGGYGGDRSGGGYGGDR------GGGYGGDRGGGYGGDRGGGYGGDRGGYG 487
              G SG    G +G   +  G  GD         G    RG    G RG G+        
Sbjct: 1453 QHGESGSTVHGRHG---TTHGQTGDTTRHAHYHHGKSTQRGSSTTGRRGSGH--SESSDS 1507

Query: 488  GDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDR----GGYGGDRSRGGYGG 533
                GG     G   G  G   G+      DR     G  GD +R  Y G
Sbjct: 1508 EVHSGGSHTHSGHTHGQSGSQHGESESIIHDRHRITHGQTGDTTRHSYSG 1557



 Score = 80.9 bits (198), Expect = 3e-15
 Identities = 147/648 (22%), Positives = 219/648 (33%), Gaps = 77/648 (11%)

Query: 10  SGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQSQSGYSQSYGG 69
           S GE+  YS+  + G+      S S     Q   SS G        Y +S  G+S S GG
Sbjct: 135 SEGEEHGYSSGHSRGTVKCRHGSNSRRLGRQGNLSSSGNQEGSQKRYHRSSCGHSWS-GG 193

Query: 70  YENQKQSSYSQQPYNNQGQQQNMESSGSQ---GGRAPSYDQPDYGQQDSYDQQSGYDQH- 125
            +    SS   +   N+        SG +   G  + S+++  +G      + SG++ + 
Sbjct: 194 KDRHGSSSVELRERINKSHISPSRESGEEYESGSGSNSWERKGHGGLSCGLETSGHESNS 253

Query: 126 -QGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVS----RYGEDNRGY--- 177
            Q    EQ        S    ++S+     N S   +      S    R+G     +   
Sbjct: 254 TQSRIREQKLGSSCSGSGDSGRRSHACGYSNSSGCGRPQNASSSCQSHRFGGQGNQFSYI 313

Query: 178 -GGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDADSE-------SD 229
             G Q G +G  G+     G  +G    +          R YG R +   +       + 
Sbjct: 314 QSGCQSGIKGGQGHGCVSGGQPSGCGQPESNPCSQSYSQRGYGARENGQPQNCGGQWRTG 373

Query: 230 NSDNNTIFVQGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATVS 289
           +S ++     G G   S       +   G    +  +     N ++  D        + S
Sbjct: 374 SSQSSCCGQYGSGGSQSCSNGQHEYGSCGRFSNSSSS-----NEFSKCDQYGSGSSQSTS 428

Query: 290 FDDPPSAKAAIDWFDGKEF--------HGNIIKVSFATRRPEFMRGGGSGGGRRGRGGYR 341
           F+   +  +    F+            H +    S    +     G  SG G+ G G  +
Sbjct: 429 FEQHGTGLSQSSGFEQHVCGSGQTCGQHESTSSQSLGYDQHGSSSGKTSGFGQHGSGSGQ 488

Query: 342 GRG-GFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCN------QCNEPRPEDS---RPSG 391
             G G  G G    SG     + S  +  F +  S +        +E R   S   +   
Sbjct: 489 SSGFGQCGSGSGQSSGFGQHGSVSGQSSGFGQHGSVSGQSSGFGQHESRSRQSSYGQHGS 548

Query: 392 GDFRGRGYG--GERGYRGRGGRG---GDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGY 446
           G  +  GYG  G R   G G  G   G   G+G   SG G        G  SG  SG G 
Sbjct: 549 GSSQSSGYGQYGSRETSGFGQHGLGSGQSTGFGQYGSGSGQSSGFGQHGSGSGQSSGFGQ 608

Query: 447 GGDRSG-GGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDR 505
              RSG   YG    G       G +G  +  G+G  + G G  +  G+ G  G   G  
Sbjct: 609 HESRSGQSSYGQHSSGSSQSSGYGQHGSRQTSGFG--QHGSGSSQSTGF-GQYGSGSGQS 665

Query: 506 GGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSGYGGDRSGGYG--GDRSG--GGYG-- 559
            G+G    G  G   G+G   SR G+     G  G+G  +S GYG  G  SG   G+G  
Sbjct: 666 SGFGQHVSG-SGQSSGFGQHESRSGHSS--YGQHGFGSSQSSGYGQHGSSSGQTSGFGQH 722

Query: 560 ----------GDRGGGYG-----GDRGGYGGKMGGRNDYRNDQRNRPY 592
                     G  G G G     G  G   G+  G   + +      Y
Sbjct: 723 ELSSGQSSSFGQHGSGSGQSSGFGQHGSGSGQSSGFGQHESRSGQSSY 770



 Score = 80.5 bits (197), Expect = 4e-15
 Identities = 148/589 (25%), Positives = 212/589 (35%), Gaps = 85/589 (14%)

Query: 2    SDSGSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQSQS 61
            S S  YGQ G      + +G      +  +S  YSG+GQ    S     SG+  +G + S
Sbjct: 1007 SQSSGYGQHGSSSGQTTGFGQ-----HRSSSGQYSGFGQ--HGSGSDQSSGFGQHG-TGS 1058

Query: 62   GYSQSYGGYENQ-KQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQQS 120
            G S  +G YE++ +QSSY Q   +   Q       GS  G+   + Q   G      Q S
Sbjct: 1059 GQSSGFGQYESRSRQSSYGQHG-SGSSQSSGYGQHGSNSGQTSGFGQHRPGS----GQSS 1113

Query: 121  GYDQHQGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSRYGEDNRGYGGS 180
            G+ Q+ GS   QS+   QH S +        +   ++ H  + R   S YG+   G G S
Sbjct: 1114 GFGQY-GSGSGQSSGFGQHGSGT-------GKSSGFAQH--EYRSGQSSYGQ--HGTGSS 1161

Query: 181  QGGGRGRGGYDKDGRGPMT--GSSGGDRGGFKNFGGH-RDYGPRTDADSESDNSDNNTIF 237
            Q  G G+    + G GP T  G        F + G H  D G  T        S  +T  
Sbjct: 1162 QSSGCGQ---HESGSGPTTSFGQHVSGSDNFSSSGQHISDSGQSTGFGQYGSGSGQST-- 1216

Query: 238  VQGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATVSFDDPPSAK 297
              GLG+G S  QV       G  +T   T    IN      +G+ +   T S        
Sbjct: 1217 --GLGQGES-QQVESGSTVHGRQET---THGQTINTTRHSQSGQGQSTQTGSRVTRRRRS 1270

Query: 298  AAIDWFDGKEFHGNII---KVSFATRRPEFMRGGGSGGGRR-----GRGGYRGRGGFQGR 349
            +  +  D  E H  +         T+        GS   RR     G+ G   R G  G 
Sbjct: 1271 SQSENSD-SEVHSKVSHRHSEHIHTQAGSHYPKSGSTVRRRQGTTHGQRGDTTRHGHSGH 1329

Query: 350  GGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGRG 409
            G   ++G     + + G   F+  ++          DS    G    R +  E+ +   G
Sbjct: 1330 GQSTQTG-----SRTSGRQRFSHSDA---------TDSEVHSG-VSHRPHSQEQTHSQAG 1374

Query: 410  GRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRGG 469
             + G+      +R    Y        G +G+ +G G+    SG G    RG    G RG 
Sbjct: 1375 SQHGESESTVHERHETTY--------GQTGEATGHGH----SGHGQSTQRGSRTTGRRGS 1422

Query: 470  GY--GGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDR-GGYGGDRGGYGGD-----RGG 521
            G+    D     GG       ++  G  G + G  G    G  G   G  GD        
Sbjct: 1423 GHSESSDSEVHSGGSHRPQSQEQTHGQAGSQHGESGSTVHGRHGTTHGQTGDTTRHAHYH 1482

Query: 522  YGGDRSRG-GYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDRGGGYGGD 569
            +G    RG    G RG G     D     GG  +  G+   + G   G+
Sbjct: 1483 HGKSTQRGSSTTGRRGSGHSESSDSEVHSGGSHTHSGHTHGQSGSQHGE 1531



 Score = 55.8 bits (133), Expect = 1e-07
 Identities = 132/623 (21%), Positives = 189/623 (30%), Gaps = 110/623 (17%)

Query: 10   SGGEQQSYS---TYGNPGSQ--------------GYGQ----ASQSYSGYGQTTDSSYGQ 48
            SGG  + +S   TYG  GSQ               +GQ       S+SG+GQ+T    G 
Sbjct: 1586 SGGSHRPHSREHTYGQAGSQHEEPEFTVHERHGTTHGQIGDTTGHSHSGHGQSTQR--GS 1643

Query: 49   NYSGYSSYGQSQSGYSQSYGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQP 108
              +G      S+S  S+ + G  +        Q  +  GQ +++          P     
Sbjct: 1644 RTTGRQRSSHSESSDSEVHSGVSHTHTGHTHGQAGSQHGQSESI---------VPERHGT 1694

Query: 109  DYGQQDSYDQQSGYDQHQGSYDEQSN-----YDQQHDSYSQNQQSYHSQRENYSHHTQDD 163
             +GQ     + + Y  H G   +  +         H  YS + + Y      +S HT   
Sbjct: 1695 THGQTGDTTRHAHY--HHGLTTQTGSRTTGRRGSGHSEYS-DSEGYSGVSHTHSGHTHGQ 1751

Query: 164  RRDVSRYGE------DNRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRD 217
             R  S++GE      +  G    Q G   R  +   G+   TGS    R   +   GH +
Sbjct: 1752 AR--SQHGESESIVHERHGTIHGQTGDTTRHAHSGHGQSTQTGS----RTTGRRSSGHSE 1805

Query: 218  YGPRTDADSESDNSDNNTIFVQGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDK 277
            Y     +DSE  +  +     +G   G +  Q GE      I+     T        T  
Sbjct: 1806 Y-----SDSEGHSGFSQRPHSRGHTHGQAGSQHGE---SESIVDERHGT--------THG 1849

Query: 278  DTGKPKGEATVSFDDPPSAKAAIDWFDGKEFHGNIIKVSFATRRPEFMRGGGSGGGRRGR 337
             TG   G +                   +  HG   +   +T          S       
Sbjct: 1850 QTGDTSGHS-------------------QSGHGQSTQSGSSTTGRRRSGHSESSDSEVHS 1890

Query: 338  GGYRGRGGFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGR 397
            GG     G        + G+              +     +   P    +  +G    GR
Sbjct: 1891 GGSHTHSGHTHSQARSQHGESESTVHKRHQTTHGQTGDTTEHGHPSHGQTIQTGSRTTGR 1950

Query: 398  GYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYG-------GDR 450
               G   Y    G  G    + G  + G  G      G    +R G  +G          
Sbjct: 1951 RGSGHSEYSDSEGPSGVSHTHSG-HTHGQAGSHYPESGSSVHERHGTTHGQTADTTRHGH 2009

Query: 451  SGGGYGGDRGGGYGGDRGGGYGG-DRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYG 509
            SG G    RG    G R  G+       G+ G    + G   G  G   G  G       
Sbjct: 2010 SGHGQSTQRGSRTTGRRASGHSEYSDSEGHSGVSHTHSGHAHGQAGSQHGESGSSVHERH 2069

Query: 510  GDRGGYGGD-----RGGYGGDRSRGG-YGGDRGGGSGYGGDRS--GGYGGDRSGGGYG-- 559
            G   G  GD       G+G    RG    G RG G     D     G     SG  YG  
Sbjct: 2070 GTTHGQTGDTTRHAHSGHGQSTQRGSRTAGRRGSGHSESSDSEVHSGVSHTHSGHTYGQA 2129

Query: 560  ----GDRGGGYGGDRGGYGGKMG 578
                G+ G    G +G   G+ G
Sbjct: 2130 RSQHGESGSAIHGRQGTIHGQTG 2152



 Score = 55.8 bits (133), Expect = 1e-07
 Identities = 128/573 (22%), Positives = 183/573 (31%), Gaps = 81/573 (14%)

Query: 12   GEQQS--YSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQSQSGYSQSYGG 69
            GE +S  +  +G    Q       ++SG+GQ+T +  G   +G  S G S+  YS S G 
Sbjct: 1757 GESESIVHERHGTIHGQTGDTTRHAHSGHGQSTQT--GSRTTGRRSSGHSE--YSDSEG- 1811

Query: 70   YENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQ------QDSYDQQSGYD 123
                  S +SQ+P++   +      +GSQ G + S     +G         S   QSG+ 
Sbjct: 1812 -----HSGFSQRPHS---RGHTHGQAGSQHGESESIVDERHGTTHGQTGDTSGHSQSGHG 1863

Query: 124  QHQGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSRYGEDNRGYGG---- 179
            Q   S    +   +   S S + + +      +S HT    R  S++GE           
Sbjct: 1864 QSTQSGSSTTGRRRSGHSESSDSEVHSGGSHTHSGHTHSQAR--SQHGESESTVHKRHQT 1921

Query: 180  --SQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDADSESDNSDNNTIF 237
               Q G     G+   G+   TGS    R G     GH +Y     +DSE  +  ++T  
Sbjct: 1922 THGQTGDTTEHGHPSHGQTIQTGSRTTGRRG----SGHSEY-----SDSEGPSGVSHT-- 1970

Query: 238  VQGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATVSFDDPPSAK 297
                  G +  Q G  + + G     +          T +      G++T         +
Sbjct: 1971 ----HSGHTHGQAGSHYPESGSSVHERHGTTHGQTADTTRHGHSGHGQSTQRGSRTTGRR 2026

Query: 298  AA-IDWFDGKEFHGNIIKVSFATRRPEFMRGGGSGGGRRGRGGYRGRGGFQGRGGDPKSG 356
            A+    +   E H  +          +     GS  G  G   +   G   G+ GD    
Sbjct: 2027 ASGHSEYSDSEGHSGVSHTHSGHAHGQ----AGSQHGESGSSVHERHGTTHGQTGDTTRH 2082

Query: 357  DWVCPNPSC--GNMNFARRNSCNQCNEPRPEDSRPSGG---DFRGRGYGGERGYRGRGG- 410
                   S   G+    RR S          DS    G      G  YG  R   G  G 
Sbjct: 2083 AHSGHGQSTQRGSRTAGRRGS----GHSESSDSEVHSGVSHTHSGHTYGQARSQHGESGS 2138

Query: 411  ----RGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGD 466
                R G   G  GD +  G      SG G S        G  RS      D        
Sbjct: 2139 AIHGRQGTIHGQTGDTTRHG-----QSGHGQSTQTGSRTTGRQRSSHSESSD-------- 2185

Query: 467  RGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDR 526
                   +    + G      G R G  G    G  G   G  GD   +     GYG   
Sbjct: 2186 --SEVHSEASPTHSGHTHSQAGSRHGQSGSSGHGRQGTTHGQTGDTTRHA--HYGYGQST 2241

Query: 527  SRGG-YGGDRGGGSGYGGDRSGGYGGDRSGGGY 558
             RG    G RG G     D      G  +  G+
Sbjct: 2242 QRGSRTTGRRGSGHSESSDSEVHSWGSHTHSGH 2274



 Score = 55.5 bits (132), Expect = 1e-07
 Identities = 130/616 (21%), Positives = 206/616 (33%), Gaps = 95/616 (15%)

Query: 3    DSGSYGQSGGEQQSYSTYGNPGSQGYGQA----SQSYSGYGQTTDSSYGQNYSGYSSYGQ 58
            D+  +  SG  Q + +     G +  G +    S+ +SG+ Q   S    +    S +G+
Sbjct: 1776 DTTRHAHSGHGQSTQTGSRTTGRRSSGHSEYSDSEGHSGFSQRPHSRGHTHGQAGSQHGE 1835

Query: 59   SQSGYSQSYGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQ 118
            S+S   + +G    Q   +     ++  G  Q+ +S  S  GR  S      G  +S D 
Sbjct: 1836 SESIVDERHGTTHGQTGDT---SGHSQSGHGQSTQSGSSTTGRRRS------GHSESSDS 1886

Query: 119  Q---SGYDQHQGSYDEQ--SNYDQQHDSYSQNQQSYHSQRENYSHH--------TQDDRR 165
            +    G   H G    Q  S + +   +  +  Q+ H Q  + + H         Q   R
Sbjct: 1887 EVHSGGSHTHSGHTHSQARSQHGESESTVHKRHQTTHGQTGDTTEHGHPSHGQTIQTGSR 1946

Query: 166  DVSRYGEDNRGYGGSQGG---GRGRGGYDKDGRG---PMTGSSGGDRGGFKN-------- 211
               R G  +  Y  S+G         G+     G   P +GSS  +R G  +        
Sbjct: 1947 TTGRRGSGHSEYSDSEGPSGVSHTHSGHTHGQAGSHYPESGSSVHERHGTTHGQTADTTR 2006

Query: 212  --FGGH--------RDYGPRTDADSESDNSDNNTIFVQGLGEGVSTDQVGEFFKQIGII- 260
                GH        R  G R    SE  +S+ ++  V     G +  Q G    + G   
Sbjct: 2007 HGHSGHGQSTQRGSRTTGRRASGHSEYSDSEGHS-GVSHTHSGHAHGQAGSQHGESGSSV 2065

Query: 261  -----KTNKKTGKPMINLYTDKDTGKPKGEATVSFDDPPSAKAAIDWFDGKEFHGNIIKV 315
                  T+ +TG    + ++       +G  T        ++++       E H  +   
Sbjct: 2066 HERHGTTHGQTGDTTRHAHSGHGQSTQRGSRTAGRRGSGHSESS-----DSEVHSGVSHT 2120

Query: 316  ----SFATRRPEFMRGGGSGGGRR----GRGGYRGRGGFQGRGGDPKSGDWVCPNPSCGN 367
                ++   R +    G +  GR+    G+ G   R G  G G   ++G     + + G 
Sbjct: 2121 HSGHTYGQARSQHGESGSAIHGRQGTIHGQTGDTTRHGQSGHGQSTQTG-----SRTTGR 2175

Query: 368  MNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGRGGRG--GDRGGYGGD---R 422
               +   S +  +E   E S    G    +  G   G  G  G G  G   G  GD    
Sbjct: 2176 QRSSHSESSD--SEVHSEASPTHSGHTHSQA-GSRHGQSGSSGHGRQGTTHGQTGDTTRH 2232

Query: 423  SGGGYGGDRSSGGGYSGDR-SGGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGG 481
            +  GYG     G   +G R SG     D     +G     G+   + G      G    G
Sbjct: 2233 AHYGYGQSTQRGSRTTGRRGSGHSESSDSEVHSWGSHTHSGHIQGQAGSQQRQPGSTVHG 2292

Query: 482  DRGGYGGDRGGGYGGDRGGYG-----GDRGGYGGDRGGYGGDRGGYGGDR--SRGGYGGD 534
                  G  G        GYG     G R         +  +R  +G  +    G YG  
Sbjct: 2293 RLETTHGQTGDTTRHGHSGYGQSTQTGSRSSRASHFQSHSSERQRHGSSQVWKHGSYGPA 2352

Query: 535  R--GGGSGYGGDRSGG 548
                G +GYG   SGG
Sbjct: 2353 EYDYGHTGYG--PSGG 2366



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 131/652 (20%), Positives = 211/652 (32%), Gaps = 111/652 (17%)

Query: 2    SDSGSYGQSGGEQ-QSYSTYGNPGSQGYGQASQS----YSGYGQTTDSSYGQNYSGYSSY 56
            S   ++ Q+G +  +S ST        YGQ  ++    +SG+GQ+T    G   +G    
Sbjct: 1365 SQEQTHSQAGSQHGESESTVHERHETTYGQTGEATGHGHSGHGQSTQR--GSRTTGRRGS 1422

Query: 57   GQSQSGYSQSYGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPS----YDQPDYGQ 112
            G S+S  S+ + G  ++ QS           Q+Q    +GSQ G + S         +GQ
Sbjct: 1423 GHSESSDSEVHSGGSHRPQS-----------QEQTHGQAGSQHGESGSTVHGRHGTTHGQ 1471

Query: 113  QDSYDQQSGYDQHQGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSRYGE 172
                 + + Y   + +    S   ++   +S++  S      +++H      +  S++GE
Sbjct: 1472 TGDTTRHAHYHHGKSTQRGSSTTGRRGSGHSESSDSEVHSGGSHTHSGHTHGQSGSQHGE 1531

Query: 173  ------DNRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDADS 226
                  D       Q G   R  Y    +   TGS    R           +   TD++ 
Sbjct: 1532 SESIIHDRHRITHGQTGDTTRHSYSGHEQTTQTGSRTTGR-------QRTSHSESTDSEV 1584

Query: 227  ESDNSDNNTIFVQGLGEGVSTDQVGEF---------FKQIGIIKTNKKTGKPMINLYTDK 277
             S  S          G+  S  +  EF           QIG    +  +G         +
Sbjct: 1585 HSGGSHRPHSREHTYGQAGSQHEEPEFTVHERHGTTHGQIGDTTGHSHSGHGQSTQRGSR 1644

Query: 278  DTGKPKGEATVSFDDPPSAKAAIDWFDGKEFHG----------NII---------KVSFA 318
             TG+ +   + S D      + +        HG          +I+         +    
Sbjct: 1645 TTGRQRSSHSESSDS--EVHSGVSHTHTGHTHGQAGSQHGQSESIVPERHGTTHGQTGDT 1702

Query: 319  TRRPEFMRG-----GGSGGGRRGRG--------GYRG---------RGGFQGRGGDPKSG 356
            TR   +  G     G    GRRG G        GY G          G  + + G+ +S 
Sbjct: 1703 TRHAHYHHGLTTQTGSRTTGRRGSGHSEYSDSEGYSGVSHTHSGHTHGQARSQHGESESI 1762

Query: 357  DWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRG-YGGERGYRGRGGRGGDR 415
                     G      R++ +   +     SR +G    G   Y    G+ G   R   R
Sbjct: 1763 VHERHGTIHGQTGDTTRHAHSGHGQSTQTGSRTTGRRSSGHSEYSDSEGHSGFSQRPHSR 1822

Query: 416  GGYGGDRSGGGYGGDRS---SGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRGGGYG 472
            G   G ++G  +G   S      G +  ++G   G  +SG G     G    G R  G+ 
Sbjct: 1823 GHTHG-QAGSQHGESESIVDERHGTTHGQTGDTSGHSQSGHGQSTQSGSSTTGRRRSGHS 1881

Query: 473  GDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRG----------GYGGDRGGYGGDRGG- 521
                       GG     G  +   R  +G              G  GD   +G    G 
Sbjct: 1882 ESSDSEV--HSGGSHTHSGHTHSQARSQHGESESTVHKRHQTTHGQTGDTTEHGHPSHGQ 1939

Query: 522  --YGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDRGGGYGGDRG 571
                G R+     G RG G     D  G  G   +  G+   + G +  + G
Sbjct: 1940 TIQTGSRTT----GRRGSGHSEYSDSEGPSGVSHTHSGHTHGQAGSHYPESG 1987



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 60/244 (24%), Positives = 98/244 (40%), Gaps = 34/244 (13%)

Query: 2    SDSGSYGQSGGEQQSYS--TYGNPGSQGYGQASQSYSG-----YGQTTDSSYGQNYSGYS 54
            S+S       G   ++S  TYG   SQ +G++  +  G     +GQT D++      G S
Sbjct: 2106 SESSDSEVHSGVSHTHSGHTYGQARSQ-HGESGSAIHGRQGTIHGQTGDTTR----HGQS 2160

Query: 55   SYGQSQSGYSQSYGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQD 114
             +GQS    S++ G    +++SS+S+    +   + + E+S +  G   S     +GQ  
Sbjct: 2161 GHGQSTQTGSRTTG----RQRSSHSE----SSDSEVHSEASPTHSGHTHSQAGSRHGQSG 2212

Query: 115  SYDQQSGYDQHQGSYDEQSNYDQQHDSYSQNQQSYHSQR---ENYSHHTQDDRRDVSRYG 171
            S    SG+ + QG+   Q+    +H  Y   Q +    R      S H++    +V  +G
Sbjct: 2213 S----SGHGR-QGTTHGQTGDTTRHAHYGYGQSTQRGSRTTGRRGSGHSESSDSEVHSWG 2267

Query: 172  EDNRG--YGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDADSESD 229
                     G  G  + + G    GR   T    GD        GH  YG  T   S S 
Sbjct: 2268 SHTHSGHIQGQAGSQQRQPGSTVHGRLETTHGQTGD----TTRHGHSGYGQSTQTGSRSS 2323

Query: 230  NSDN 233
             + +
Sbjct: 2324 RASH 2327



 Score = 38.5 bits (88), Expect = 0.018
 Identities = 73/296 (24%), Positives = 93/296 (31%), Gaps = 47/296 (15%)

Query: 291 DDPPSAKAAI---DWFDGKEFHGNIIKVSFATRRPEFMRGGGSGGGRRGRGGYRGRGGFQ 347
           +D P  K+      W +G+E HG     S    R       GS   R GR G     G Q
Sbjct: 120 EDTPGHKSGYRHSSWSEGEE-HG----YSSGHSRGTVKCRHGSNSRRLGRQGNLSSSGNQ 174

Query: 348 GRGGDPKSGDWVCPNPSCGNMNFARRNSCN---QCNEPRPEDSRPSGGDFRGRGYGGERG 404
             G   +     C +   G  +    +S     + N+     SR SG ++          
Sbjct: 175 -EGSQKRYHRSSCGHSWSGGKDRHGSSSVELRERINKSHISPSRESGEEYES-------- 225

Query: 405 YRGRGGRGGDRGGYGGDRSGGGYGGDRS----------------SGGGYSGDRSGGGYGG 448
             G G    +R G+GG   G    G  S                SG G SG RS      
Sbjct: 226 --GSGSNSWERKGHGGLSCGLETSGHESNSTQSRIREQKLGSSCSGSGDSGRRSHACGYS 283

Query: 449 DRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGG--YGGDRGGYGGDRG 506
           + SG G   +        R GG G        G + G  G +G G   GG   G G    
Sbjct: 284 NSSGCGRPQNASSSCQSHRFGGQGNQFSYIQSGCQSGIKGGQGHGCVSGGQPSGCGQPES 343

Query: 507 ---GYGGDRGGYGGDRGGY----GGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSG 555
                   + GYG    G     GG    G       G  G GG +S   G    G
Sbjct: 344 NPCSQSYSQRGYGARENGQPQNCGGQWRTGSSQSSCCGQYGSGGSQSCSNGQHEYG 399



 Score = 37.0 bits (84), Expect = 0.051
 Identities = 94/488 (19%), Positives = 153/488 (31%), Gaps = 59/488 (12%)

Query: 6    SYGQSGGE-QQSYSTYGNPGSQGYGQASQSYSGYGQTTDSS----YGQNYSGYSSYGQSQ 60
            ++GQ+G   +  + ++G     G     +  SG+ + +DS         +SG++ +GQ+ 
Sbjct: 1922 THGQTGDTTEHGHPSHGQTIQTGSRTTGRRGSGHSEYSDSEGPSGVSHTHSGHT-HGQAG 1980

Query: 61   SGYSQSYGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQQS 120
            S Y +S      +  +++ Q     +        S  +G R        + +    +  S
Sbjct: 1981 SHYPESGSSVHERHGTTHGQTADTTRHGHSGHGQSTQRGSRTTGRRASGHSEYSDSEGHS 2040

Query: 121  GYDQ-HQGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSRYGEDNRGYGG 179
            G    H G    Q+         SQ+ +S  S  E +   T     D +R+     G   
Sbjct: 2041 GVSHTHSGHAHGQAG--------SQHGESGSSVHERHG-TTHGQTGDTTRHAHSGHGQ-S 2090

Query: 180  SQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDADSESDNSDNNTIFVQ 239
            +Q G R  G   + G G    S      G  +      YG       ES ++ +      
Sbjct: 2091 TQRGSRTAG---RRGSGHSESSDSEVHSGVSHTHSGHTYGQARSQHGESGSAIHG----- 2142

Query: 240  GLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATVSFDDPPSAKAA 299
                     + G    Q G    + ++G         + TG+ +   + S D    ++A+
Sbjct: 2143 ---------RQGTIHGQTGDTTRHGQSGHGQSTQTGSRTTGRQRSSHSESSDSEVHSEAS 2193

Query: 300  IDWFDGKEFHGNIIKVSFATRRPEFMRGGGSGGGRR----GRGGYRGRGGFQGRGGDPKS 355
                     H         +R  +    G SG GR+    G+ G   R    G G   + 
Sbjct: 2194 -------PTHSGHTHSQAGSRHGQ---SGSSGHGRQGTTHGQTGDTTRHAHYGYGQSTQR 2243

Query: 356  GDWVCPNPSCGNM--------NFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRG 407
            G         G+         ++                 R  G    GR      G  G
Sbjct: 2244 GSRTTGRRGSGHSESSDSEVHSWGSHTHSGHIQGQAGSQQRQPGSTVHGR-LETTHGQTG 2302

Query: 408  RGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDR 467
               R G   GYG     G      S    +S +R   G       G Y G     YG   
Sbjct: 2303 DTTRHG-HSGYGQSTQTGSRSSRASHFQSHSSERQRHGSSQVWKHGSY-GPAEYDYGHTG 2360

Query: 468  GGGYGGDR 475
             G  GG R
Sbjct: 2361 YGPSGGSR 2368


>gi|195972866 keratin 10 [Homo sapiens]
          Length = 584

 Score =  122 bits (307), Expect = 7e-28
 Identities = 73/144 (50%), Positives = 77/144 (53%), Gaps = 15/144 (10%)

Query: 407 GRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGD 466
           G G  GG  GG GG   GGGYGG  SSGGG SG   GGG+GG  SGGGYGG   G  GG 
Sbjct: 455 GEGSSGG--GGRGGGSFGGGYGGG-SSGGGSSGGGHGGGHGGS-SGGGYGGGSSG--GGS 508

Query: 467 RGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGY-GGDRGGYGGDRGGYGGD 525
            GGGYGG      G   GG+GG   GGYGG  G  GG  GGY GG  GG     GGYGG 
Sbjct: 509 SGGGYGG------GSSSGGHGGSSSGGYGG--GSSGGGGGGYGGGSSGGGSSSGGGYGGG 560

Query: 526 RSRGGYGGDRGGGSGYGGDRSGGY 549
            S GG+     G  G    +   Y
Sbjct: 561 SSSGGHKSSSSGSVGESSSKGPRY 584



 Score =  121 bits (303), Expect = 2e-27
 Identities = 66/131 (50%), Positives = 69/131 (52%), Gaps = 14/131 (10%)

Query: 439 GDRSGGGYGGDRSGGGYGG--DRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGG 496
           G   GGG GG   GGGYGG    GG  GG  GGG+GG  GGGYGG   G GG  GGGYGG
Sbjct: 457 GSSGGGGRGGGSFGGGYGGGSSGGGSSGGGHGGGHGGSSGGGYGGGSSG-GGSSGGGYGG 515

Query: 497 DRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGG 556
                G   GG+G      G   GGYGG  S GG GG  GG SG G    GGYGG  S G
Sbjct: 516 -----GSSSGGHG------GSSSGGYGGGSSGGGGGGYGGGSSGGGSSSGGGYGGGSSSG 564

Query: 557 GYGGDRGGGYG 567
           G+     G  G
Sbjct: 565 GHKSSSSGSVG 575



 Score =  120 bits (300), Expect = 5e-27
 Identities = 70/136 (51%), Positives = 75/136 (55%), Gaps = 17/136 (12%)

Query: 445 GYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGD 504
           G G    GG  GG  GGGYGG   GG  G  GGG+GG   G+GG  GGGYGG   G G  
Sbjct: 455 GEGSSGGGGRGGGSFGGGYGGGSSGG--GSSGGGHGG---GHGGSSGGGYGGGSSGGGSS 509

Query: 505 RGGYGGDRGGYGGDRGGYGGDRSRGGYGG--DRGGGSGYGGDRSGGYGGDRSGGGYGGDR 562
            GGYGG     G   GG+GG  S GGYGG    GGG GYGG  SG  GG  SGGGYGG  
Sbjct: 510 GGGYGG-----GSSSGGHGGS-SSGGYGGGSSGGGGGGYGGGSSG--GGSSSGGGYGG-- 559

Query: 563 GGGYGGDRGGYGGKMG 578
           G   GG +    G +G
Sbjct: 560 GSSSGGHKSSSSGSVG 575



 Score =  112 bits (279), Expect = 1e-24
 Identities = 68/146 (46%), Positives = 74/146 (50%), Gaps = 9/146 (6%)

Query: 432 SSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRG 491
           SS   YS  RSGGG GG   GGG GG         +G   GG   GG+ G     G   G
Sbjct: 6   SSSKHYSSSRSGGGGGGGGCGGG-GGVSSLRISSSKGSLGGGFSSGGFSGGSFSRGSSGG 64

Query: 492 GGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSGYGGDRSGGY-- 549
           G +GG  GGYGG  GG+GG     G  RG YG     G YGG  GGGS  GG   GG   
Sbjct: 65  GCFGGSSGGYGG-LGGFGG-----GSFRGSYGSSSFGGSYGGSFGGGSFGGGSFGGGSFG 118

Query: 550 GGDRSGGGYGGDRGGGYGGDRGGYGG 575
           GG   GGG+GG  GGG+GGD G   G
Sbjct: 119 GGGFGGGGFGGGFGGGFGGDGGLLSG 144



 Score =  112 bits (279), Expect = 1e-24
 Identities = 65/133 (48%), Positives = 68/133 (51%), Gaps = 17/133 (12%)

Query: 391 GGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDR 450
           GG F G GYGG  G  G G  GG  GG  G  SGGGYGG  S GG      SGGGYGG  
Sbjct: 466 GGSFGG-GYGG--GSSGGGSSGGGHGGGHGGSSGGGYGGGSSGGGS-----SGGGYGGGS 517

Query: 451 SGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGG 510
           S GG+GG   GGYGG   GG     GGGYGG   G G   GGGYGG     G   GG+  
Sbjct: 518 SSGGHGGSSSGGYGGGSSGG----GGGGYGGGSSGGGSSSGGGYGG-----GSSSGGHKS 568

Query: 511 DRGGYGGDRGGYG 523
              G  G+    G
Sbjct: 569 SSSGSVGESSSKG 581



 Score =  107 bits (266), Expect = 4e-23
 Identities = 65/135 (48%), Positives = 69/135 (51%), Gaps = 18/135 (13%)

Query: 404 GYRGRGGRGGDR--GGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGY------ 455
           G  G GGRGG    GGYGG  SGGG  G    GGG+ G  SGGGYGG  SGGG       
Sbjct: 457 GSSGGGGRGGGSFGGGYGGGSSGGGSSGG-GHGGGHGGS-SGGGYGGGSSGGGSSGGGYG 514

Query: 456 GGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGY 515
           GG   GG+GG   GGYG   GG  GG  GGYGG   GG     GGYGG     G   GG+
Sbjct: 515 GGSSSGGHGGSSSGGYG---GGSSGGGGGGYGGGSSGGGSSSGGGYGG-----GSSSGGH 566

Query: 516 GGDRGGYGGDRSRGG 530
                G  G+ S  G
Sbjct: 567 KSSSSGSVGESSSKG 581



 Score = 94.0 bits (232), Expect = 4e-19
 Identities = 68/151 (45%), Positives = 76/151 (50%), Gaps = 22/151 (14%)

Query: 399 YGGERGYRG-RGGRGGDRGGYGGDRSGGGYGGDR--SSGGGYSGDRSGGGYGGDRSGGGY 455
           Y   + Y   R G GG  GG GG   GGG    R  SS G   G  S GG+    SGG +
Sbjct: 5   YSSSKHYSSSRSGGGGGGGGCGG---GGGVSSLRISSSKGSLGGGFSSGGF----SGGSF 57

Query: 456 G-GDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDR-GGGYGGDRGGYGGDRGGYGGDRG 513
             G  GGG  G   GGYGG  G G G  RG YG    GG YGG  GG     G +GG  G
Sbjct: 58  SRGSSGGGCFGGSSGGYGGLGGFGGGSFRGSYGSSSFGGSYGGSFGGGSFGGGSFGG--G 115

Query: 514 GYGGDRGGYGGDRSRGGYGGDRGGGSGYGGD 544
            +GG  GG+GG    GG+GG  G G G+GGD
Sbjct: 116 SFGG--GGFGG----GGFGG--GFGGGFGGD 138



 Score = 92.0 bits (227), Expect = 1e-18
 Identities = 57/110 (51%), Positives = 59/110 (53%), Gaps = 16/110 (14%)

Query: 470 GYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRG 529
           G G   GGG GG      G  GGGYGG   G G   GG+GG  GG  G  GGYGG  S G
Sbjct: 455 GEGSSGGGGRGG------GSFGGGYGGGSSGGGSSGGGHGGGHGGSSG--GGYGGGSSGG 506

Query: 530 GYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDRGGGYGGDRGGYGGKMGG 579
           G     GGG G GG  SGG+GG  S GGYGG   G  GG  GGYGG   G
Sbjct: 507 G---SSGGGYG-GGSSSGGHGGS-SSGGYGG---GSSGGGGGGYGGGSSG 548



 Score = 91.3 bits (225), Expect = 2e-18
 Identities = 67/145 (46%), Positives = 76/145 (52%), Gaps = 28/145 (19%)

Query: 407 GRGGRGGDRGGYGGDRS----------GGGYGGDRSSGGGYSGDRSGGG-YGGDRSGGGY 455
           G GG GG  GG GG  S          GGG+     SGG +S   SGGG +GG  S GGY
Sbjct: 17  GGGGGGGGCGGGGGVSSLRISSSKGSLGGGFSSGGFSGGSFSRGSSGGGCFGG--SSGGY 74

Query: 456 GGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGY 515
           GG  G G G  RG       GG YGG  GG G   GG +GG  G +GG  GG+GG  GG+
Sbjct: 75  GGLGGFGGGSFRGSYGSSSFGGSYGGSFGG-GSFGGGSFGG--GSFGG--GGFGG--GGF 127

Query: 516 GGDRGGYGGDRSRGGYGGDRGGGSG 540
           G   GG+G     GG+GGD G  SG
Sbjct: 128 G---GGFG-----GGFGGDGGLLSG 144



 Score = 84.7 bits (208), Expect = 2e-16
 Identities = 58/131 (44%), Positives = 65/131 (49%), Gaps = 21/131 (16%)

Query: 400 GGERGYRGRGGRGG--------DRGGYGGDRSGGGYGGDR----SSGGGYSGDRSGG--- 444
           GG  G  G GG GG         +G  GG  S GG+ G      SSGGG  G  SGG   
Sbjct: 17  GGGGGGGGCGGGGGVSSLRISSSKGSLGGGFSSGGFSGGSFSRGSSGGGCFGGSSGGYGG 76

Query: 445 --GYGGDRSGGGYGGDR-GGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGD-RGG 500
             G+GG    G YG    GG YGG  GGG  G  GG +GG   G GG  GGG+GG   GG
Sbjct: 77  LGGFGGGSFRGSYGSSSFGGSYGGSFGGGSFG--GGSFGGGSFGGGGFGGGGFGGGFGGG 134

Query: 501 YGGDRGGYGGD 511
           +GGD G   G+
Sbjct: 135 FGGDGGLLSGN 145



 Score = 82.8 bits (203), Expect = 8e-16
 Identities = 66/182 (36%), Positives = 77/182 (42%), Gaps = 57/182 (31%)

Query: 327 GGGSGGGRRGRGGYRGRGGFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPED 386
           GGG GGG  G GG                                        +  R   
Sbjct: 17  GGGGGGGGCGGGG--------------------------------------GVSSLRISS 38

Query: 387 SRPS-GGDFRGRGYGG---ERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRS 442
           S+ S GG F   G+ G    RG  G G  GG  GGYGG    GG+GG  S  G Y     
Sbjct: 39  SKGSLGGGFSSGGFSGGSFSRGSSGGGCFGGSSGGYGG---LGGFGGG-SFRGSYGSSSF 94

Query: 443 GGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYG 502
           GG YGG   GG +G   GG +G   GG +GG   GG+GG  GG+GG  GGG+GGD G   
Sbjct: 95  GGSYGGSFGGGSFG---GGSFG---GGSFGG---GGFGG--GGFGGGFGGGFGGDGGLLS 143

Query: 503 GD 504
           G+
Sbjct: 144 GN 145



 Score = 72.0 bits (175), Expect = 1e-12
 Identities = 54/152 (35%), Positives = 59/152 (38%), Gaps = 28/152 (18%)

Query: 328 GGSGGGRRGRGGYRGRGGFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDS 387
           G SGGG RG G + G  G    GG    G     +       +   +S            
Sbjct: 457 GSSGGGGRGGGSFGGGYGGGSSGGGSSGGGHGGGHGGSSGGGYGGGSS------------ 504

Query: 388 RPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYG 447
              GG   G GYGG     G GG     GGYGG  SGGG       GGGY G  SG   G
Sbjct: 505 ---GGGSSGGGYGGGSSSGGHGGSSS--GGYGGGSSGGG-------GGGYGGGSSG---G 549

Query: 448 GDRSGGGY-GGDRGGGYGGDRGGGYGGDRGGG 478
           G  SGGGY GG   GG+     G  G     G
Sbjct: 550 GSSSGGGYGGGSSSGGHKSSSSGSVGESSSKG 581



 Score = 56.2 bits (134), Expect = 8e-08
 Identities = 46/111 (41%), Positives = 48/111 (43%), Gaps = 19/111 (17%)

Query: 471 YGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGY-GGDRSRG 529
           Y   R GG GG     GG  GGG G         +G  GG     G   GG+ GG  SRG
Sbjct: 11  YSSSRSGGGGG-----GGGCGGGGGVSSLRISSSKGSLGG-----GFSSGGFSGGSFSRG 60

Query: 530 GYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDRGG-GYGGDRGGYGGKMGG 579
             GG   GGS      SGGYGG   G G G  RG  G     G YGG  GG
Sbjct: 61  SSGGGCFGGS------SGGYGG-LGGFGGGSFRGSYGSSSFGGSYGGSFGG 104



 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 43/123 (34%), Positives = 48/123 (39%), Gaps = 8/123 (6%)

Query: 326 RGGGSGGGRRGRGGYRG--RGGFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPR 383
           RGGGS GG  G G   G   GG  G G    SG       S G  +       +      
Sbjct: 464 RGGGSFGGGYGGGSSGGGSSGGGHGGGHGGSSGGGYGGGSSGGGSSGGGYGGGSSSGGHG 523

Query: 384 PEDSRPSGGDFRGRGYGGERGYRGRGGRGGDR-GGYGGDRSGGGYGGDRSSGGGYSGDRS 442
              S   GG   G G GG  G  G  G G    GGYGG  S GG+   +SS  G  G+ S
Sbjct: 524 GSSSGGYGGGSSGGGGGGYGG--GSSGGGSSSGGGYGGGSSSGGH---KSSSSGSVGESS 578

Query: 443 GGG 445
             G
Sbjct: 579 SKG 581



 Score = 38.5 bits (88), Expect = 0.018
 Identities = 23/58 (39%), Positives = 28/58 (48%), Gaps = 2/58 (3%)

Query: 171 GEDNRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDADSES 228
           G  + GYGG   GG G GGY     G    SSGG  GG  + GGH+     +  +S S
Sbjct: 524 GSSSGGYGGGSSGG-GGGGYGGGSSGG-GSSSGGGYGGGSSSGGHKSSSSGSVGESSS 579



 Score = 37.7 bits (86), Expect = 0.030
 Identities = 29/79 (36%), Positives = 31/79 (39%), Gaps = 2/79 (2%)

Query: 2   SDSGSYGQ-SGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQSQ 60
           S  G YG  S G   S   YG   S G G    S  GYG  +    G  Y G SS G S 
Sbjct: 494 SSGGGYGGGSSGGGSSGGGYGGGSSSG-GHGGSSSGGYGGGSSGGGGGGYGGGSSGGGSS 552

Query: 61  SGYSQSYGGYENQKQSSYS 79
           SG     G      +SS S
Sbjct: 553 SGGGYGGGSSSGGHKSSSS 571



 Score = 37.4 bits (85), Expect = 0.039
 Identities = 21/45 (46%), Positives = 23/45 (51%), Gaps = 3/45 (6%)

Query: 171 GEDNRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGH 215
           G    G+GG  GG  G GGY     G   GSSGG  GG  + GGH
Sbjct: 481 GSSGGGHGGGHGGSSG-GGYGGGSSG--GGSSGGGYGGGSSSGGH 522



 Score = 36.6 bits (83), Expect = 0.067
 Identities = 36/114 (31%), Positives = 39/114 (34%), Gaps = 7/114 (6%)

Query: 327 GGGSGGGRRGRGGYRGRGGFQGRG-GDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPE 385
           GG SGGG  G G   G GG  G G G   SG       S G       +  +  +     
Sbjct: 475 GGSSGGGSSGGGHGGGHGGSSGGGYGGGSSGG----GSSGGGYGGGSSSGGHGGSSSGGY 530

Query: 386 DSRPSGGDFRGRGYGGERGYRGRGGR--GGDRGGYGGDRSGGGYGGDRSSGGGY 437
               SGG   G G G   G    GG   GG   G     S G  G   S G  Y
Sbjct: 531 GGGSSGGGGGGYGGGSSGGGSSSGGGYGGGSSSGGHKSSSSGSVGESSSKGPRY 584



 Score = 35.8 bits (81), Expect = 0.11
 Identities = 21/50 (42%), Positives = 25/50 (50%), Gaps = 3/50 (6%)

Query: 166 DVSRYGEDNRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGH 215
           ++  Y     G G S GGGRG G +   G G   GSSGG   G  + GGH
Sbjct: 445 EIQTYRSLLEGEGSSGGGGRGGGSF---GGGYGGGSSGGGSSGGGHGGGH 491



 Score = 34.7 bits (78), Expect = 0.25
 Identities = 27/84 (32%), Positives = 31/84 (36%), Gaps = 2/84 (2%)

Query: 171 GEDNRGYGG--SQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDADSES 228
           G    GYGG  S GG  G G       G   GSS G  GG  + GG   YG  +     S
Sbjct: 493 GSSGGGYGGGSSGGGSSGGGYGGGSSSGGHGGSSSGGYGGGSSGGGGGGYGGGSSGGGSS 552

Query: 229 DNSDNNTIFVQGLGEGVSTDQVGE 252
                      G  +  S+  VGE
Sbjct: 553 SGGGYGGGSSSGGHKSSSSGSVGE 576



 Score = 33.9 bits (76), Expect = 0.43
 Identities = 26/72 (36%), Positives = 28/72 (38%), Gaps = 5/72 (6%)

Query: 2   SDSGSYGQSGGEQQSYSTYGNPGSQGYGQASQS-----YSGYGQTTDSSYGQNYSGYSSY 56
           S  GS G   G   S   +G   S GYG  S       Y G      SS G  Y G SS 
Sbjct: 504 SGGGSSGGGYGGGSSSGGHGGSSSGGYGGGSSGGGGGGYGGGSSGGGSSSGGGYGGGSSS 563

Query: 57  GQSQSGYSQSYG 68
           G  +S  S S G
Sbjct: 564 GGHKSSSSGSVG 575



 Score = 33.5 bits (75), Expect = 0.56
 Identities = 19/45 (42%), Positives = 21/45 (46%), Gaps = 1/45 (2%)

Query: 171 GEDNRGYGGSQGGGRGRGGYDKDGR-GPMTGSSGGDRGGFKNFGG 214
           G     +GG  GGG   GG    G  G   GSSGG  GG  + GG
Sbjct: 463 GRGGGSFGGGYGGGSSGGGSSGGGHGGGHGGSSGGGYGGGSSGGG 507



 Score = 33.5 bits (75), Expect = 0.56
 Identities = 20/45 (44%), Positives = 22/45 (48%), Gaps = 2/45 (4%)

Query: 171 GEDNRGYGGSQGGGRGRG--GYDKDGRGPMTGSSGGDRGGFKNFG 213
           G    G+GGS GGG G G  G    G G   GSS G  GG  + G
Sbjct: 485 GGHGGGHGGSSGGGYGGGSSGGGSSGGGYGGGSSSGGHGGSSSGG 529



 Score = 33.1 bits (74), Expect = 0.74
 Identities = 33/129 (25%), Positives = 43/129 (33%), Gaps = 16/129 (12%)

Query: 8   GQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSS--YGQSQSGYSQ 65
           G SGG  +   ++G     GYG  S      G ++   +G  + G S   YG   SG   
Sbjct: 457 GSSGGGGRGGGSFGG----GYGGGSSG----GGSSGGGHGGGHGGSSGGGYGGGSSGGGS 508

Query: 66  SYGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQQSGYDQH 125
           S GGY     S        + G        GS GG    Y     G   S     G    
Sbjct: 509 SGGGYGGGSSSG------GHGGSSSGGYGGGSSGGGGGGYGGGSSGGGSSSGGGYGGGSS 562

Query: 126 QGSYDEQSN 134
            G +   S+
Sbjct: 563 SGGHKSSSS 571



 Score = 33.1 bits (74), Expect = 0.74
 Identities = 32/103 (31%), Positives = 37/103 (35%), Gaps = 7/103 (6%)

Query: 2   SDSGSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQSQS 61
           S  G YG  GG     S+ G  G  G+G +S    G G +   S G  Y G SS G    
Sbjct: 468 SFGGGYG--GGSSGGGSSGGGHGG-GHGGSSGGGYGGGSSGGGSSGGGYGGGSSSGGHGG 524

Query: 62  GYSQSYGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPS 104
             S  YGG      S      Y          S G  GG + S
Sbjct: 525 SSSGGYGG----GSSGGGGGGYGGGSSGGGSSSGGGYGGGSSS 563



 Score = 32.3 bits (72), Expect = 1.3
 Identities = 21/49 (42%), Positives = 23/49 (46%), Gaps = 3/49 (6%)

Query: 171 GEDNRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYG 219
           GE + G GG +GGG   GGY     G   GSSGG  GG         YG
Sbjct: 455 GEGSSG-GGGRGGGSFGGGYGGGSSGG--GSSGGGHGGGHGGSSGGGYG 500



 Score = 32.0 bits (71), Expect = 1.6
 Identities = 25/71 (35%), Positives = 33/71 (46%), Gaps = 7/71 (9%)

Query: 2   SDSGSYG---QSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQ 58
           S  GS G    SGG      + G+ G   +G +S  Y G G     S+  +Y G SS+G 
Sbjct: 38  SSKGSLGGGFSSGGFSGGSFSRGSSGGGCFGGSSGGYGGLGGFGGGSFRGSY-GSSSFGG 96

Query: 59  SQSGYSQSYGG 69
           S   Y  S+GG
Sbjct: 97  S---YGGSFGG 104



 Score = 31.2 bits (69), Expect = 2.8
 Identities = 21/47 (44%), Positives = 24/47 (51%), Gaps = 6/47 (12%)

Query: 170 YGEDNRGYGG--SQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGG 214
           +G  + GYGG    GGG  RG Y   G     GS GG  GG  +FGG
Sbjct: 67  FGGSSGGYGGLGGFGGGSFRGSY---GSSSFGGSYGGSFGG-GSFGG 109



 Score = 30.8 bits (68), Expect = 3.7
 Identities = 24/67 (35%), Positives = 30/67 (44%)

Query: 4   SGSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQSQSGY 63
           S S G SGG     S+ G  G  G+G  S   S    +   SYG ++ G S  G S  G 
Sbjct: 56  SFSRGSSGGGCFGGSSGGYGGLGGFGGGSFRGSYGSSSFGGSYGGSFGGGSFGGGSFGGG 115

Query: 64  SQSYGGY 70
           S   GG+
Sbjct: 116 SFGGGGF 122



 Score = 30.4 bits (67), Expect = 4.8
 Identities = 20/48 (41%), Positives = 21/48 (43%), Gaps = 1/48 (2%)

Query: 303 FDGKEFHGNIIKVSFATRRPEFMRGGGSGGGRRGRGGYRGRGGFQGRG 350
           F G  F G+    SF         GG  GGG  G GG  G GGF G G
Sbjct: 80  FGGGSFRGSYGSSSFGGSYGGSFGGGSFGGGSFG-GGSFGGGGFGGGG 126


>gi|109255251 loricrin [Homo sapiens]
          Length = 312

 Score =  120 bits (302), Expect = 3e-27
 Identities = 109/306 (35%), Positives = 116/306 (37%), Gaps = 72/306 (23%)

Query: 324 FMRGGGSGGGRRGRG-GYRGRGGFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEP 382
           F  GGGSGGG  G G GY G GG+ G G         C   S G         C      
Sbjct: 36  FFGGGGSGGGSSGSGCGYSGGGGYSGGG---------CGGGSSGGGGGGGIGGC------ 80

Query: 383 RPEDSRPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRS 442
                        G G GG   Y G GG  G  GG G   SGGG  G  SSGGG S    
Sbjct: 81  -------------GGGSGGSVKYSGGGGSSG--GGSGCFSSGGGGSGCFSSGGGGSSGGG 125

Query: 443 GGGY---GGDRSGGGYG--GDRGGGY---------------GGDRGGGYGGDRGGGYGGD 482
            G +   GG  SGGG G     GGG+               GG  GGG G    GG GG 
Sbjct: 126 SGCFSSGGGGSSGGGSGCFSSGGGGFSGQAVQCQSYGGVSSGGSSGGGSGCFSSGGGGGS 185

Query: 483 RGGYGGDRGGGYGGDRGGYGGD--------------RGGYGGDRGGYGGDRGGYGGDRSR 528
             GY G   G  GG  GG G                +  YGG   G GG  G   G  S 
Sbjct: 186 VCGYSGGGSGCGGGSSGGSGSGYVSSQQVTQTSCAPQPSYGGGSSGGGGSGGS--GCFSS 243

Query: 529 GGYGGDRGGGSGYGGDRSG---GYGGDRSGGGYGGDRGGGYGGDRGGYGGKMGGRNDYRN 585
           GG GG  G G G  G  SG     GG   GGG  G  GGG G   GG G   G    ++ 
Sbjct: 244 GGGGGSSGCGGGSSGIGSGCIISGGGSVCGGGSSG--GGGGGSSVGGSGSGKGVPICHQT 301

Query: 586 DQRNRP 591
            Q+  P
Sbjct: 302 QQKQAP 307



 Score =  120 bits (300), Expect = 5e-27
 Identities = 99/251 (39%), Positives = 106/251 (42%), Gaps = 56/251 (22%)

Query: 381 EPRPEDSRPSGGDFRGRGYGGER-GYRGRGGRGGDRGGYG-GDRSGGGYGGDRSSGGGYS 438
           +P  +  + SGG   G G GG   G+ G GG GG   G G G   GGGY G    GGG S
Sbjct: 11  QPPVDCVKTSGGGGGGGGSGGGGCGFFGGGGSGGGSSGSGCGYSGGGGYSGG-GCGGGSS 69

Query: 439 GDRSGGGYGGDRSGGGYGGD-RGGGYGGDRGGGYG--GDRGGGYGGDRGGYGGDRGGGYG 495
           G   GGG GG   GGG GG  +  G GG  GGG G     GGG G    G GG  GGG G
Sbjct: 70  GGGGGGGIGG--CGGGSGGSVKYSGGGGSSGGGSGCFSSGGGGSGCFSSGGGGSSGGGSG 127

Query: 496 ----GDRGGYGGDRGGYGGDRGGY---------------GGDRGGYGGDRSRGGYGGD-- 534
               G  G  GG  G +    GG+               GG  GG  G  S GG GG   
Sbjct: 128 CFSSGGGGSSGGGSGCFSSGGGGFSGQAVQCQSYGGVSSGGSSGGGSGCFSSGGGGGSVC 187

Query: 535 --RGGGSGYGGDRSGG---------------------YGGDRSGGGYGGDRG----GGYG 567
              GGGSG GG  SGG                     YGG  SGGG  G  G    GG G
Sbjct: 188 GYSGGGSGCGGGSSGGSGSGYVSSQQVTQTSCAPQPSYGGGSSGGGGSGGSGCFSSGGGG 247

Query: 568 GDRGGYGGKMG 578
           G  G  GG  G
Sbjct: 248 GSSGCGGGSSG 258



 Score =  116 bits (290), Expect = 7e-26
 Identities = 82/187 (43%), Positives = 85/187 (45%), Gaps = 30/187 (16%)

Query: 422 RSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGY--GGDRGGGYGGDRGGGY 479
           ++ GG GG   SGGG  G   GGG GG  SG G G   GGGY  GG  GG  GG  GGG 
Sbjct: 18  KTSGGGGGGGGSGGGGCGFFGGGGSGGGSSGSGCGYSGGGGYSGGGCGGGSSGGGGGGGI 77

Query: 480 GGDRGGYGGD-----RGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGD 534
           GG  GG GG       GG  GG  G +    GG G    G GG  GG  G  S GG GG 
Sbjct: 78  GGCGGGSGGSVKYSGGGGSSGGGSGCFSSGGGGSGCFSSGGGGSSGGGSGCFSSGG-GGS 136

Query: 535 RGGGSG------------------YGGDRSGGYGGDRSG----GGYGGDRGGGYGGDRGG 572
            GGGSG                  YGG  SGG  G  SG    GG GG   G  GG  G 
Sbjct: 137 SGGGSGCFSSGGGGFSGQAVQCQSYGGVSSGGSSGGGSGCFSSGGGGGSVCGYSGGGSGC 196

Query: 573 YGGKMGG 579
            GG  GG
Sbjct: 197 GGGSSGG 203



 Score =  112 bits (279), Expect = 1e-24
 Identities = 87/185 (47%), Positives = 89/185 (48%), Gaps = 25/185 (13%)

Query: 410 GRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGY-GGDRGGGYGGDRG 468
           G GG  GG GG   G G+ G   SGGG SG  SG GY G   GGGY GG  GGG  G  G
Sbjct: 21  GGGGGGGGSGG--GGCGFFGGGGSGGGSSG--SGCGYSG---GGGYSGGGCGGGSSGGGG 73

Query: 469 GGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSR 528
           GG  G  GGG GG     GG  GG  GG  G +    GG G    G GG  GG  G  S 
Sbjct: 74  GGGIGGCGGGSGGSVKYSGG--GGSSGGGSGCFSSGGGGSGCFSSGGGGSSGGGSGCFSS 131

Query: 529 GGYGGDRGGGSGY----GGDRSG------GYGGDRSGGGYGGDRG----GGYGGDRGGYG 574
           GG GG  GGGSG     GG  SG       YGG  SGG  GG  G    GG GG   GY 
Sbjct: 132 GG-GGSSGGGSGCFSSGGGGFSGQAVQCQSYGGVSSGGSSGGGSGCFSSGGGGGSVCGYS 190

Query: 575 GKMGG 579
           G   G
Sbjct: 191 GGGSG 195



 Score = 61.2 bits (147), Expect = 3e-09
 Identities = 38/78 (48%), Positives = 39/78 (50%), Gaps = 8/78 (10%)

Query: 506 GGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDRGGG 565
           GG GG  G  GG  G +GG    G  GG  G G GY G   GGY G   GG  GG  GGG
Sbjct: 21  GGGGGGGGSGGGGCGFFGGG---GSGGGSSGSGCGYSG--GGGYSG---GGCGGGSSGGG 72

Query: 566 YGGDRGGYGGKMGGRNDY 583
            GG  GG GG  GG   Y
Sbjct: 73  GGGGIGGCGGGSGGSVKY 90



 Score = 61.2 bits (147), Expect = 3e-09
 Identities = 84/291 (28%), Positives = 95/291 (32%), Gaps = 26/291 (8%)

Query: 178 GGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDADSESDNSDNNTIF 237
           GG  GGG G GG    G G   G S G   G+   GG+   G        S       I 
Sbjct: 22  GGGGGGGSGGGGCGFFGGGGSGGGSSGSGCGYSGGGGYSGGG---CGGGSSGGGGGGGIG 78

Query: 238 VQGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATVSFDDPPSAK 297
             G G G S    G      G        G       +        G    S     S+ 
Sbjct: 79  GCGGGSGGSVKYSGGGGSSGGGSGCFSSGGGGSGCFSSGGGGSSGGGSGCFSSGGGGSSG 138

Query: 298 AAIDWFD--GKEFHGNIIKV-SFATRRPEFMRGGG-----SGGGRRGRGGYRGRGGFQGR 349
                F   G  F G  ++  S+         GGG     SGGG     GY G G   G 
Sbjct: 139 GGSGCFSSGGGGFSGQAVQCQSYGGVSSGGSSGGGSGCFSSGGGGGSVCGYSGGGSGCGG 198

Query: 350 GGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGRG 409
           G    SG     +          + SC     P+P      GG   G G  G  G    G
Sbjct: 199 GSSGGSGSGYVSSQQ------VTQTSC----APQPS----YGGGSSGGGGSGGSGCFSSG 244

Query: 410 GRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRG 460
           G GG   G GG  SG G G   S GG   G  S GG GG  S GG G  +G
Sbjct: 245 G-GGGSSGCGGGSSGIGSGCIISGGGSVCGGGSSGGGGGGSSVGGSGSGKG 294



 Score = 38.5 bits (88), Expect = 0.018
 Identities = 58/216 (26%), Positives = 66/216 (30%), Gaps = 46/216 (21%)

Query: 5   GSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSG-----YSSYGQS 59
           G  G  GG   S    G  GS G G    S  G G    SS G   SG     +SS G  
Sbjct: 76  GIGGCGGGSGGSVKYSGGGGSSGGGSGCFSSGGGGSGCFSSGGGGSSGGGSGCFSSGGGG 135

Query: 60  QSG-----YSQSYGGYENQK---QSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYG 111
            SG     +S   GG+  Q    QS        + G      SSG  GG    Y     G
Sbjct: 136 SSGGGSGCFSSGGGGFSGQAVQCQSYGGVSSGGSSGGGSGCFSSGGGGGSVCGYSGGGSG 195

Query: 112 QQDSYDQQSGYDQHQGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSRYG 171
                   SG                    Y  +QQ            TQ        YG
Sbjct: 196 CGGGSSGGSG------------------SGYVSSQQV-----------TQTSCAPQPSYG 226

Query: 172 EDNRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRG 207
             + G GGS G     G +   G G  +G  GG  G
Sbjct: 227 GGSSGGGGSGGS----GCFSSGGGGGSSGCGGGSSG 258



 Score = 37.7 bits (86), Expect = 0.030
 Identities = 69/255 (27%), Positives = 86/255 (33%), Gaps = 56/255 (21%)

Query: 176 GYGGSQGGGRGRGGYDKDGRGPMT----GSSGGDRGGFKNFGGHRDYGPRTDADSESDNS 231
           G GGS GGG G       G G  +    GSSGG  G F + GG    G      S     
Sbjct: 92  GGGGSSGGGSGCFSSGGGGSGCFSSGGGGSSGGGSGCFSSGGGGSSGGGSGCFSSGGGGF 151

Query: 232 DNNTIFVQGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATVSFD 291
               +  Q  G GVS+   G      G   +    G   +  Y+   +G   G +  S  
Sbjct: 152 SGQAVQCQSYG-GVSSG--GSSGGGSGCFSSGGGGGS--VCGYSGGGSGCGGGSSGGSGS 206

Query: 292 DPPSAKAAIDWFDGKEFHGNIIKVSFATRRPEFMRGGGSGGGRRGRGGYRGRGGFQGRGG 351
              S++                +V+  +  P+   GGGS GG    GG  G G F   GG
Sbjct: 207 GYVSSQ----------------QVTQTSCAPQPSYGGGSSGG----GGSGGSGCFSSGGG 246

Query: 352 DPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGRGGR 411
              SG        CG  +    + C             SGG   G   GG     G  G 
Sbjct: 247 GGSSG--------CGGGSSGIGSGC-----------IISGG---GSVCGG-----GSSGG 279

Query: 412 GGDRGGYGGDRSGGG 426
           GG     GG  SG G
Sbjct: 280 GGGGSSVGGSGSGKG 294



 Score = 36.2 bits (82), Expect = 0.087
 Identities = 37/122 (30%), Positives = 43/122 (35%), Gaps = 5/122 (4%)

Query: 4   SGSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQSQSGY 63
           SG  G SGG    +S+ G  GS G G    S  G G +  +   Q+Y G SS G S  G 
Sbjct: 116 SGGGGSSGGGSGCFSS-GGGGSSGGGSGCFSSGGGGFSGQAVQCQSYGGVSSGGSSGGGS 174

Query: 64  SQSYGGYENQKQSSYSQQPYNNQGQQQNMESSG----SQGGRAPSYDQPDYGQQDSYDQQ 119
                G        YS       G       SG     Q  +     QP YG   S    
Sbjct: 175 GCFSSGGGGGSVCGYSGGGSGCGGGSSGGSGSGYVSSQQVTQTSCAPQPSYGGGSSGGGG 234

Query: 120 SG 121
           SG
Sbjct: 235 SG 236


>gi|109452587 family with sequence similarity 98, member B isoform 1
           [Homo sapiens]
          Length = 433

 Score =  116 bits (290), Expect = 7e-26
 Identities = 68/107 (63%), Positives = 71/107 (66%), Gaps = 8/107 (7%)

Query: 452 GGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGD 511
           GGG GG  GGG GG RGGG GG   GG+GG  GG+GG  GGG GG  GG GG RGG+ G 
Sbjct: 332 GGGRGGWGGGGGGGGRGGGGGGGGRGGWGGGGGGWGGGGGGG-GGWGGGGGGGRGGFQG- 389

Query: 512 RGGYGGDRGGYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGY 558
           RG YGG RGGYGG   RGGYGG RG G  YGG   GG GG   GGGY
Sbjct: 390 RGDYGG-RGGYGG---RGGYGG-RGYGDPYGGGGGGG-GGGGGGGGY 430



 Score =  111 bits (278), Expect = 2e-24
 Identities = 66/109 (60%), Positives = 70/109 (64%), Gaps = 7/109 (6%)

Query: 441 RSGGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGG 500
           + GGG  G   GGG GG RGGG GG   GG+GG  GGG+GG  GG GG  GGG GG RGG
Sbjct: 329 QEGGGGRGGWGGGGGGGGRGGGGGGGGRGGWGGG-GGGWGGGGGG-GGGWGGGGGGGRGG 386

Query: 501 YGGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSGYGGDRSGGY 549
           + G RG YGG RGGYGG RGGYGG      YGG  GGG G GG   GGY
Sbjct: 387 FQG-RGDYGG-RGGYGG-RGGYGGRGYGDPYGG--GGGGGGGGGGGGGY 430



 Score =  105 bits (263), Expect = 9e-23
 Identities = 74/130 (56%), Positives = 78/130 (60%), Gaps = 31/130 (23%)

Query: 412 GGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRGGGY 471
           GG RGG+GG   GGG GG           R GGG GG R  GG+GG  GGG+GG  GGG 
Sbjct: 332 GGGRGGWGG---GGGGGG-----------RGGGGGGGGR--GGWGGG-GGGWGG--GGGG 372

Query: 472 GGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGY 531
           GG  GGG GG RGG+ G   G YGG RGGYGG RGGYGG   GYG   GG GG    GG 
Sbjct: 373 GGGWGGGGGGGRGGFQG--RGDYGG-RGGYGG-RGGYGG--RGYGDPYGGGGG----GGG 422

Query: 532 GGDRGGGSGY 541
           GG  GGG GY
Sbjct: 423 GG--GGGGGY 430



 Score =  103 bits (258), Expect = 3e-22
 Identities = 59/105 (56%), Positives = 61/105 (58%), Gaps = 8/105 (7%)

Query: 468 GGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRS 527
           GGG GG  GGG GG RGG GG      GG RGG+GG  GG+GG  GG GG  GG GG R 
Sbjct: 332 GGGRGGWGGGGGGGGRGGGGG------GGGRGGWGGGGGGWGGGGGGGGGWGGGGGGGRG 385

Query: 528 RGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDRGGGYGGDRGG 572
                GD GG  GYGG   GGYGG   G  YGG  GGG GG  GG
Sbjct: 386 GFQGRGDYGGRGGYGG--RGGYGGRGYGDPYGGGGGGGGGGGGGG 428



 Score =  101 bits (251), Expect = 2e-21
 Identities = 67/130 (51%), Positives = 72/130 (55%), Gaps = 17/130 (13%)

Query: 377 NQCNEPRPE----DSRPSGGDFRGR-GYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDR 431
           N+   P PE      R  GG  RG  G GG  G RG GG GG RGG+GG   GGG+GG  
Sbjct: 313 NEIEPPPPEMPPWQKRQEGGGGRGGWGGGGGGGGRGGGGGGGGRGGWGG--GGGGWGGGG 370

Query: 432 SSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRG 491
             GGG+ G   GGG GG +  G YGG   GGYGG   GGYG   G GYG   GG GG  G
Sbjct: 371 GGGGGWGGG-GGGGRGGFQGRGDYGG--RGGYGG--RGGYG---GRGYGDPYGGGGG--G 420

Query: 492 GGYGGDRGGY 501
           GG GG  GGY
Sbjct: 421 GGGGGGGGGY 430



 Score =  100 bits (249), Expect = 4e-21
 Identities = 72/136 (52%), Positives = 77/136 (56%), Gaps = 22/136 (16%)

Query: 381 EPRPEDSRPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGD 440
           EP P +  P     R  G GG  G+ G GG GG RGG GG   GGG GG    GGG+   
Sbjct: 316 EPPPPEMPP--WQKRQEGGGGRGGWGGGGGGGG-RGGGGG---GGGRGGWGGGGGGW--- 366

Query: 441 RSGGGYGGDRSGGGYGGDRGGGYGGDRG-GGYGGDRGGGYGGDRGGYGGDRGGGYGGDRG 499
             GGG GG   GGG+GG  GGG GG +G G YGG   GGYGG RGGYG   G GYG   G
Sbjct: 367 --GGGGGG---GGGWGGGGGGGRGGFQGRGDYGG--RGGYGG-RGGYG---GRGYGDPYG 415

Query: 500 GYGGDRGGYGGDRGGY 515
           G GG  GG GG  GGY
Sbjct: 416 G-GGGGGGGGGGGGGY 430



 Score = 92.0 bits (227), Expect = 1e-18
 Identities = 48/82 (58%), Positives = 54/82 (65%), Gaps = 5/82 (6%)

Query: 495 GGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRS 554
           GG RGG+GG  GG G   GG GG RGG+GG    GG+GG  GGG G+GG   GG GG + 
Sbjct: 332 GGGRGGWGGGGGGGGRGGGGGGGGRGGWGG--GGGGWGGGGGGGGGWGGGGGGGRGGFQG 389

Query: 555 GGGYGGDRGGGYGGDRGGYGGK 576
            G YGG   GGYGG RGGYGG+
Sbjct: 390 RGDYGGR--GGYGG-RGGYGGR 408



 Score = 84.0 bits (206), Expect = 4e-16
 Identities = 46/77 (59%), Positives = 51/77 (66%), Gaps = 4/77 (5%)

Query: 502 GGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGD 561
           GG RGG+GG  GG GG RGG GG   RGG+GG  GGG G GG   GG+GG   GGG GG 
Sbjct: 332 GGGRGGWGG--GGGGGGRGGGGGGGGRGGWGGG-GGGWGGGGGGGGGWGGG-GGGGRGGF 387

Query: 562 RGGGYGGDRGGYGGKMG 578
           +G G  G RGGYGG+ G
Sbjct: 388 QGRGDYGGRGGYGGRGG 404



 Score = 77.0 bits (188), Expect = 4e-14
 Identities = 56/133 (42%), Positives = 60/133 (45%), Gaps = 41/133 (30%)

Query: 327 GGGSGGGRRGRGGYRGRGGFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPED 386
           GGG GGGR G GG  GRGG+ G GG    G                              
Sbjct: 340 GGGGGGGRGGGGGGGGRGGWGGGGGGWGGGG----------------------------- 370

Query: 387 SRPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGY 446
               GG + G G GG  G++GRG  GG RGGYGG    GGYG     G GY GD  GGG 
Sbjct: 371 --GGGGGWGGGGGGGRGGFQGRGDYGG-RGGYGG---RGGYG-----GRGY-GDPYGGGG 418

Query: 447 GGDRSGGGYGGDR 459
           GG   GGG GG R
Sbjct: 419 GGGGGGGGGGGYR 431



 Score = 76.3 bits (186), Expect = 8e-14
 Identities = 57/150 (38%), Positives = 60/150 (40%), Gaps = 42/150 (28%)

Query: 322 PEFMRGGGSGGGRRGRGGYRGRGGFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNE 381
           P + +    GGGR G GG  G GG  G GG    G W                       
Sbjct: 323 PPWQKRQEGGGGRGGWGGGGGGGGRGGGGGGGGRGGW----------------------- 359

Query: 382 PRPEDSRPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDR 441
                    GG   G G+GG     G GG GG  GG GG R G    GD    GGY G  
Sbjct: 360 --------GGG---GGGWGG-----GGGGGGGWGGGGGGGRGGFQGRGDYGGRGGYGG-- 401

Query: 442 SGGGYGGDRSGGGYGGDRGGGYGGDRGGGY 471
             GGYGG   G  YGG  GGG GG  GGGY
Sbjct: 402 -RGGYGGRGYGDPYGGGGGGGGGGGGGGGY 430



 Score = 70.9 bits (172), Expect = 3e-12
 Identities = 38/68 (55%), Positives = 41/68 (60%), Gaps = 6/68 (8%)

Query: 516 GGDRGGYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDRGGGYGGDRGGYGG 575
           GG RGG+GG    GG GG RGGG G GG   GG+GG   G G GG  GGG+GG  GG  G
Sbjct: 332 GGGRGGWGG----GGGGGGRGGGGGGGG--RGGWGGGGGGWGGGGGGGGGWGGGGGGGRG 385

Query: 576 KMGGRNDY 583
              GR DY
Sbjct: 386 GFQGRGDY 393



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 24/56 (42%), Positives = 27/56 (48%), Gaps = 2/56 (3%)

Query: 170 YGEDNRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDAD 225
           +G    G+GG  GGG G GG    GRG   G   GD GG   +GG   YG R   D
Sbjct: 359 WGGGGGGWGGGGGGGGGWGGGGGGGRGGFQGR--GDYGGRGGYGGRGGYGGRGYGD 412



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 23/50 (46%), Positives = 25/50 (50%)

Query: 169 RYGEDNRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDY 218
           R G   RG  G +GG  GRGGY   G G   G  GG  GG    GG+R Y
Sbjct: 384 RGGFQGRGDYGGRGGYGGRGGYGGRGYGDPYGGGGGGGGGGGGGGGYRRY 433



 Score = 39.3 bits (90), Expect = 0.010
 Identities = 24/54 (44%), Positives = 27/54 (50%), Gaps = 6/54 (11%)

Query: 171 GEDNRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFK---NFGGHRDYGPR 221
           G   RG  G  GGG G GG    G G   G  GG RGGF+   ++GG   YG R
Sbjct: 352 GGGGRGGWGGGGGGWGGGG---GGGGGWGGGGGGGRGGFQGRGDYGGRGGYGGR 402



 Score = 37.4 bits (85), Expect = 0.039
 Identities = 22/51 (43%), Positives = 23/51 (45%)

Query: 171 GEDNRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPR 221
           G    G GG +GG  G GG    G G   G  GG  GG   F G  DYG R
Sbjct: 346 GRGGGGGGGGRGGWGGGGGGWGGGGGGGGGWGGGGGGGRGGFQGRGDYGGR 396



 Score = 31.2 bits (69), Expect = 2.8
 Identities = 17/43 (39%), Positives = 20/43 (46%)

Query: 172 EDNRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGG 214
           ++  G  G  GGG G GG    G G   G  GG  GG+   GG
Sbjct: 329 QEGGGGRGGWGGGGGGGGRGGGGGGGGRGGWGGGGGGWGGGGG 371


>gi|14043072 heterogeneous nuclear ribonucleoprotein A2/B1 isoform
           B1 [Homo sapiens]
          Length = 353

 Score =  114 bits (286), Expect = 2e-25
 Identities = 111/321 (34%), Positives = 135/321 (42%), Gaps = 90/321 (28%)

Query: 236 IFVQGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATVSFDD-PP 294
           +FV G+ E      + ++F++ G I T        I + TD+ +GK +G   V+FDD  P
Sbjct: 114 LFVGGIKEDTEEHHLRDYFEEYGKIDT--------IEIITDRQSGKKRGFGFVTFDDHDP 165

Query: 295 SAKAAIDWFDGKEFHGNIIKVSFATRRPEFMRGGGSGGGRRGRGGYRGRGGFQGRGGDPK 354
             K  +  +     +G+  +V  A  R E      S   R GRG                
Sbjct: 166 VDKIVLQKYH--TINGHNAEVRKALSRQEMQEVQSS---RSGRG---------------- 204

Query: 355 SGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGRGGRGGD 414
                      GN  F               DSR  GG+F            G G     
Sbjct: 205 -----------GNFGFG--------------DSRGGGGNF------------GPGPGSNF 227

Query: 415 RGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGG--GYGGDRGGGYGGDRGGGYG 472
           RGG        GYG  R  G GY+G   GGG GG   GG  GYGG R GGYGG  G GY 
Sbjct: 228 RGG------SDGYGSGRGFGDGYNG--YGGGPGGGNFGGSPGYGGGR-GGYGGG-GPGY- 276

Query: 473 GDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDR-GGYGGDRSRGG- 530
           G++GGGYGG    YG   GG YG   G Y  D G Y      YG  + G +GG R+ GG 
Sbjct: 277 GNQGGGYGGGYDNYG---GGNYGS--GNY-NDFGNYNQQPSNYGPMKSGNFGGSRNMGGP 330

Query: 531 YGGDRGGGSGYGGDRSGGYGG 551
           YGG   G  G GG  SGGYGG
Sbjct: 331 YGGGNYGPGGSGG--SGGYGG 349



 Score =  114 bits (286), Expect = 2e-25
 Identities = 70/156 (44%), Positives = 77/156 (49%), Gaps = 12/156 (7%)

Query: 424 GGGYG-GDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGD 482
           GG +G GD   GGG  G   G  + G   G G G   G GY G     YGG  GGG  G 
Sbjct: 204 GGNFGFGDSRGGGGNFGPGPGSNFRGGSDGYGSGRGFGDGYNG-----YGGGPGGGNFGG 258

Query: 483 RGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSGYG 542
             GYGG RGG YGG   GYG   GGYGG    YGG   G G     G Y       S YG
Sbjct: 259 SPGYGGGRGG-YGGGGPGYGNQGGGYGGGYDNYGGGNYGSGNYNDFGNYNQQP---SNYG 314

Query: 543 GDRSGGYGGDRSGGG--YGGDRGGGYGGDRGGYGGK 576
             +SG +GG R+ GG   GG+ G G  G  GGYGG+
Sbjct: 315 PMKSGNFGGSRNMGGPYGGGNYGPGGSGGSGGYGGR 350



 Score =  108 bits (271), Expect = 1e-23
 Identities = 74/158 (46%), Positives = 82/158 (51%), Gaps = 13/158 (8%)

Query: 408 RGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRS-GGGYGGDRGGGYGGD 466
           R GRGG+ G +G  R GGG  G    G G +      GYG  R  G GY G  GG  GG+
Sbjct: 200 RSGRGGNFG-FGDSRGGGGNFGP---GPGSNFRGGSDGYGSGRGFGDGYNGYGGGPGGGN 255

Query: 467 RGG--GYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYG--GDRGGYGGDRGGY 522
            GG  GYGG RGG YGG   GY G++GGGYGG    YGG   G G   D G Y      Y
Sbjct: 256 FGGSPGYGGGRGG-YGGGGPGY-GNQGGGYGGGYDNYGGGNYGSGNYNDFGNYNQQPSNY 313

Query: 523 GGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGG 560
           G  +S G +GG R  G  YGG   G  GG    GGYGG
Sbjct: 314 GPMKS-GNFGGSRNMGGPYGGGNYGP-GGSGGSGGYGG 349



 Score = 82.0 bits (201), Expect = 1e-15
 Identities = 53/112 (47%), Positives = 63/112 (56%), Gaps = 13/112 (11%)

Query: 475 RGGGYG-GDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGG 533
           RGG +G GD  G GG+ G G G +   + G   GYG  RG +G    GYGG    G  GG
Sbjct: 203 RGGNFGFGDSRGGGGNFGPGPGSN---FRGGSDGYGSGRG-FGDGYNGYGG----GPGGG 254

Query: 534 DRGGGSGYGGDRSGGYGGDRSGGGYGGDRGGGYGGDRGGYGGKMGGRNDYRN 585
           + GG  GYGG R GGYGG   G GYG ++GGGYGG    YGG   G  +Y +
Sbjct: 255 NFGGSPGYGGGR-GGYGG--GGPGYG-NQGGGYGGGYDNYGGGNYGSGNYND 302



 Score = 56.2 bits (134), Expect = 8e-08
 Identities = 46/175 (26%), Positives = 64/175 (36%), Gaps = 27/175 (15%)

Query: 18  STYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSS---YGQSQSGYSQSYGGYENQK 74
           S  G  G+ G+G +      +G    S++     GY S   +G   +GY    GG     
Sbjct: 199 SRSGRGGNFGFGDSRGGGGNFGPGPGSNFRGGSDGYGSGRGFGDGYNGYGGGPGG----- 253

Query: 75  QSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQQSGYDQHQGSYDEQSN 134
             ++   P    G+       G  GG  P Y     G    YD   G +   G+Y++  N
Sbjct: 254 -GNFGGSPGYGGGR-------GGYGGGGPGYGNQGGGYGGGYDNYGGGNYGSGNYNDFGN 305

Query: 135 YDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSRYGEDNRGYGGSQGGGRGRGG 189
           Y+QQ  +Y   +        N              YG  N G GGS GG  G GG
Sbjct: 306 YNQQPSNYGPMKSGNFGGSRNMG----------GPYGGGNYGPGGS-GGSGGYGG 349



 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 40/128 (31%), Positives = 49/128 (38%), Gaps = 14/128 (10%)

Query: 4   SGSYGQSGGEQQSYSTYGN-------PGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSY 56
           S  YG   G    Y+ YG         GS GYG     Y G G    +  G    GY +Y
Sbjct: 231 SDGYGSGRGFGDGYNGYGGGPGGGNFGGSPGYGGGRGGYGGGGPGYGNQGGGYGGGYDNY 290

Query: 57  GQSQ--SGYSQSYGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQD 114
           G     SG    +G Y NQ+ S+Y      N G  +NM   G  GG   +Y     G   
Sbjct: 291 GGGNYGSGNYNDFGNY-NQQPSNYGPMKSGNFGGSRNM--GGPYGG--GNYGPGGSGGSG 345

Query: 115 SYDQQSGY 122
            Y  +S Y
Sbjct: 346 GYGGRSRY 353



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 24/55 (43%), Positives = 29/55 (52%), Gaps = 12/55 (21%)

Query: 170 YGEDNRGYGGSQGGGR---------GRGGYDKDGRGPMTGSSGGD-RGGFKNFGG 214
           +G+   GYGG  GGG          GRGGY   G GP  G+ GG   GG+ N+GG
Sbjct: 240 FGDGYNGYGGGPGGGNFGGSPGYGGGRGGY--GGGGPGYGNQGGGYGGGYDNYGG 292



 Score = 33.9 bits (76), Expect = 0.43
 Identities = 65/266 (24%), Positives = 88/266 (33%), Gaps = 74/266 (27%)

Query: 109 DYGQQDSY----DQQSGYDQHQG--SYDEQSNYDQQHDSYSQNQQSYHS-QRENYSHHTQ 161
           +YG+ D+     D+QSG  +  G  ++D+    D+         Q YH+    N      
Sbjct: 134 EYGKIDTIEIITDRQSGKKRGFGFVTFDDHDPVDKIV------LQKYHTINGHNAEVRKA 187

Query: 162 DDRRDVSRYGEDNRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRG-------------- 207
             R+++        G GG+ G G  RGG    G GP +   GG  G              
Sbjct: 188 LSRQEMQEVQSSRSGRGGNFGFGDSRGGGGNFGPGPGSNFRGGSDGYGSGRGFGDGYNGY 247

Query: 208 ----GFKNFGGHRDYGPRTDADSESDNSDNNTIFVQGLGEGVSTDQVGEFFKQIGIIKTN 263
               G  NFGG   YG              N    QG G G   D  G           N
Sbjct: 248 GGGPGGGNFGGSPGYGGGRGGYGGGGPGYGN----QGGGYGGGYDNYG---------GGN 294

Query: 264 KKTGKPMINLYTDKDTGKPKGEATVSFDDPPSAKAAIDWFDGKEFHGNIIKVSFATRRPE 323
             +G      Y D            +++  PS             +G +   +F   R  
Sbjct: 295 YGSGN-----YNDFG----------NYNQQPSN------------YGPMKSGNFGGSR-- 325

Query: 324 FMRGGGSGGGRRGRGGYRGRGGFQGR 349
              GG  GGG  G GG  G GG+ GR
Sbjct: 326 -NMGGPYGGGNYGPGGSGGSGGYGGR 350


>gi|4504447 heterogeneous nuclear ribonucleoprotein A2/B1 isoform A2
           [Homo sapiens]
          Length = 341

 Score =  114 bits (286), Expect = 2e-25
 Identities = 111/321 (34%), Positives = 135/321 (42%), Gaps = 90/321 (28%)

Query: 236 IFVQGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATVSFDD-PP 294
           +FV G+ E      + ++F++ G I T        I + TD+ +GK +G   V+FDD  P
Sbjct: 102 LFVGGIKEDTEEHHLRDYFEEYGKIDT--------IEIITDRQSGKKRGFGFVTFDDHDP 153

Query: 295 SAKAAIDWFDGKEFHGNIIKVSFATRRPEFMRGGGSGGGRRGRGGYRGRGGFQGRGGDPK 354
             K  +  +     +G+  +V  A  R E      S   R GRG                
Sbjct: 154 VDKIVLQKYH--TINGHNAEVRKALSRQEMQEVQSS---RSGRG---------------- 192

Query: 355 SGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGRGGRGGD 414
                      GN  F               DSR  GG+F            G G     
Sbjct: 193 -----------GNFGFG--------------DSRGGGGNF------------GPGPGSNF 215

Query: 415 RGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGG--GYGGDRGGGYGGDRGGGYG 472
           RGG        GYG  R  G GY+G   GGG GG   GG  GYGG R GGYGG  G GY 
Sbjct: 216 RGG------SDGYGSGRGFGDGYNG--YGGGPGGGNFGGSPGYGGGR-GGYGGG-GPGY- 264

Query: 473 GDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDR-GGYGGDRSRGG- 530
           G++GGGYGG    YG   GG YG   G Y  D G Y      YG  + G +GG R+ GG 
Sbjct: 265 GNQGGGYGGGYDNYG---GGNYGS--GNY-NDFGNYNQQPSNYGPMKSGNFGGSRNMGGP 318

Query: 531 YGGDRGGGSGYGGDRSGGYGG 551
           YGG   G  G GG  SGGYGG
Sbjct: 319 YGGGNYGPGGSGG--SGGYGG 337



 Score =  114 bits (286), Expect = 2e-25
 Identities = 70/156 (44%), Positives = 77/156 (49%), Gaps = 12/156 (7%)

Query: 424 GGGYG-GDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGD 482
           GG +G GD   GGG  G   G  + G   G G G   G GY G     YGG  GGG  G 
Sbjct: 192 GGNFGFGDSRGGGGNFGPGPGSNFRGGSDGYGSGRGFGDGYNG-----YGGGPGGGNFGG 246

Query: 483 RGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSGYG 542
             GYGG RGG YGG   GYG   GGYGG    YGG   G G     G Y       S YG
Sbjct: 247 SPGYGGGRGG-YGGGGPGYGNQGGGYGGGYDNYGGGNYGSGNYNDFGNYNQQP---SNYG 302

Query: 543 GDRSGGYGGDRSGGG--YGGDRGGGYGGDRGGYGGK 576
             +SG +GG R+ GG   GG+ G G  G  GGYGG+
Sbjct: 303 PMKSGNFGGSRNMGGPYGGGNYGPGGSGGSGGYGGR 338



 Score =  108 bits (271), Expect = 1e-23
 Identities = 74/158 (46%), Positives = 82/158 (51%), Gaps = 13/158 (8%)

Query: 408 RGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRS-GGGYGGDRGGGYGGD 466
           R GRGG+ G +G  R GGG  G    G G +      GYG  R  G GY G  GG  GG+
Sbjct: 188 RSGRGGNFG-FGDSRGGGGNFGP---GPGSNFRGGSDGYGSGRGFGDGYNGYGGGPGGGN 243

Query: 467 RGG--GYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYG--GDRGGYGGDRGGY 522
            GG  GYGG RGG YGG   GY G++GGGYGG    YGG   G G   D G Y      Y
Sbjct: 244 FGGSPGYGGGRGG-YGGGGPGY-GNQGGGYGGGYDNYGGGNYGSGNYNDFGNYNQQPSNY 301

Query: 523 GGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGG 560
           G  +S G +GG R  G  YGG   G  GG    GGYGG
Sbjct: 302 GPMKS-GNFGGSRNMGGPYGGGNYGP-GGSGGSGGYGG 337



 Score = 82.0 bits (201), Expect = 1e-15
 Identities = 53/112 (47%), Positives = 63/112 (56%), Gaps = 13/112 (11%)

Query: 475 RGGGYG-GDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGG 533
           RGG +G GD  G GG+ G G G +   + G   GYG  RG +G    GYGG    G  GG
Sbjct: 191 RGGNFGFGDSRGGGGNFGPGPGSN---FRGGSDGYGSGRG-FGDGYNGYGG----GPGGG 242

Query: 534 DRGGGSGYGGDRSGGYGGDRSGGGYGGDRGGGYGGDRGGYGGKMGGRNDYRN 585
           + GG  GYGG R GGYGG   G GYG ++GGGYGG    YGG   G  +Y +
Sbjct: 243 NFGGSPGYGGGR-GGYGG--GGPGYG-NQGGGYGGGYDNYGGGNYGSGNYND 290



 Score = 56.2 bits (134), Expect = 8e-08
 Identities = 46/175 (26%), Positives = 64/175 (36%), Gaps = 27/175 (15%)

Query: 18  STYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSS---YGQSQSGYSQSYGGYENQK 74
           S  G  G+ G+G +      +G    S++     GY S   +G   +GY    GG     
Sbjct: 187 SRSGRGGNFGFGDSRGGGGNFGPGPGSNFRGGSDGYGSGRGFGDGYNGYGGGPGG----- 241

Query: 75  QSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQQSGYDQHQGSYDEQSN 134
             ++   P    G+       G  GG  P Y     G    YD   G +   G+Y++  N
Sbjct: 242 -GNFGGSPGYGGGR-------GGYGGGGPGYGNQGGGYGGGYDNYGGGNYGSGNYNDFGN 293

Query: 135 YDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSRYGEDNRGYGGSQGGGRGRGG 189
           Y+QQ  +Y   +        N              YG  N G GGS GG  G GG
Sbjct: 294 YNQQPSNYGPMKSGNFGGSRNMG----------GPYGGGNYGPGGS-GGSGGYGG 337



 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 40/128 (31%), Positives = 49/128 (38%), Gaps = 14/128 (10%)

Query: 4   SGSYGQSGGEQQSYSTYGN-------PGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSY 56
           S  YG   G    Y+ YG         GS GYG     Y G G    +  G    GY +Y
Sbjct: 219 SDGYGSGRGFGDGYNGYGGGPGGGNFGGSPGYGGGRGGYGGGGPGYGNQGGGYGGGYDNY 278

Query: 57  GQSQ--SGYSQSYGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQD 114
           G     SG    +G Y NQ+ S+Y      N G  +NM   G  GG   +Y     G   
Sbjct: 279 GGGNYGSGNYNDFGNY-NQQPSNYGPMKSGNFGGSRNM--GGPYGG--GNYGPGGSGGSG 333

Query: 115 SYDQQSGY 122
            Y  +S Y
Sbjct: 334 GYGGRSRY 341



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 24/55 (43%), Positives = 29/55 (52%), Gaps = 12/55 (21%)

Query: 170 YGEDNRGYGGSQGGGR---------GRGGYDKDGRGPMTGSSGGD-RGGFKNFGG 214
           +G+   GYGG  GGG          GRGGY   G GP  G+ GG   GG+ N+GG
Sbjct: 228 FGDGYNGYGGGPGGGNFGGSPGYGGGRGGY--GGGGPGYGNQGGGYGGGYDNYGG 280



 Score = 33.9 bits (76), Expect = 0.43
 Identities = 65/266 (24%), Positives = 88/266 (33%), Gaps = 74/266 (27%)

Query: 109 DYGQQDSY----DQQSGYDQHQG--SYDEQSNYDQQHDSYSQNQQSYHS-QRENYSHHTQ 161
           +YG+ D+     D+QSG  +  G  ++D+    D+         Q YH+    N      
Sbjct: 122 EYGKIDTIEIITDRQSGKKRGFGFVTFDDHDPVDKIV------LQKYHTINGHNAEVRKA 175

Query: 162 DDRRDVSRYGEDNRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRG-------------- 207
             R+++        G GG+ G G  RGG    G GP +   GG  G              
Sbjct: 176 LSRQEMQEVQSSRSGRGGNFGFGDSRGGGGNFGPGPGSNFRGGSDGYGSGRGFGDGYNGY 235

Query: 208 ----GFKNFGGHRDYGPRTDADSESDNSDNNTIFVQGLGEGVSTDQVGEFFKQIGIIKTN 263
               G  NFGG   YG              N    QG G G   D  G           N
Sbjct: 236 GGGPGGGNFGGSPGYGGGRGGYGGGGPGYGN----QGGGYGGGYDNYG---------GGN 282

Query: 264 KKTGKPMINLYTDKDTGKPKGEATVSFDDPPSAKAAIDWFDGKEFHGNIIKVSFATRRPE 323
             +G      Y D            +++  PS             +G +   +F   R  
Sbjct: 283 YGSGN-----YNDFG----------NYNQQPSN------------YGPMKSGNFGGSR-- 313

Query: 324 FMRGGGSGGGRRGRGGYRGRGGFQGR 349
              GG  GGG  G GG  G GG+ GR
Sbjct: 314 -NMGGPYGGGNYGPGGSGGSGGYGGR 338


>gi|56699482 hypothetical protein LOC25940 [Homo sapiens]
          Length = 518

 Score =  112 bits (281), Expect = 7e-25
 Identities = 80/183 (43%), Positives = 89/183 (48%), Gaps = 22/183 (12%)

Query: 409 GGRGGDRGGYG----GDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYG 464
           GGRGG RGGY     G R G   GG R   GGY     GGG G    GG   G  GGG G
Sbjct: 334 GGRGGGRGGYEHSSYGGRGGHEQGGGRGGRGGYDHGGRGGGRGNKHQGGWTDGGSGGG-G 392

Query: 465 GDRGGGY--GGDRGGGYGGDRGGYGGDRGGGYGG-----DRGGYGGDRGGYGGDR----G 513
           G + GGY   G + GGY G     GG +GGGYGG        G G   GGY  D     G
Sbjct: 393 GYQDGGYRDSGFQPGGYHGGHSS-GGYQGGGYGGFQTSSSYTGSGYQGGGYQQDNRYQDG 451

Query: 514 GYGGDR-GGYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGD-RGGGYGGDRG 571
           G+ GDR GG GG   RGG GG  G G G+GG  S  Y     GG +    + GGY  +  
Sbjct: 452 GHHGDRGGGRGGRGGRGGRGGRAGQGGGWGGRGSQNY---HQGGQFEQHFQHGGYQYNHS 508

Query: 572 GYG 574
           G+G
Sbjct: 509 GFG 511



 Score =  105 bits (261), Expect = 2e-22
 Identities = 90/223 (40%), Positives = 103/223 (46%), Gaps = 59/223 (26%)

Query: 377 NQCNEPRPE----------DSRPSGGDFRGRG------YGGERGYR---GRGGRGG-DRG 416
           N+   P PE            + +GG   GRG      YGG  G+    GRGGRGG D G
Sbjct: 310 NEIEPPPPEMPPWQKRQDGPQQQTGGRGGGRGGYEHSSYGGRGGHEQGGGRGGRGGYDHG 369

Query: 417 GYGGDRS----GGGYGGDRSSGGGYS--GDRSGG----GYGGDRSGGGYGGDRGGGYGGD 466
           G GG R     GG   G    GGGY   G R  G    GY G  S GGY   +GGGYGG 
Sbjct: 370 GRGGGRGNKHQGGWTDGGSGGGGGYQDGGYRDSGFQPGGYHGGHSSGGY---QGGGYGGF 426

Query: 467 R------GGGYGGDRGGGYGGDR----GGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYG 516
           +      G GY   +GGGY  D     GG+ GDRGGG GG RGG GG        RGG  
Sbjct: 427 QTSSSYTGSGY---QGGGYQQDNRYQDGGHHGDRGGGRGG-RGGRGG--------RGGRA 474

Query: 517 GDRGGYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYG 559
           G  GG+GG  S+  +     GG      + GGY  + SG G G
Sbjct: 475 GQGGGWGGRGSQNYH----QGGQFEQHFQHGGYQYNHSGFGQG 513



 Score =  101 bits (251), Expect = 2e-21
 Identities = 76/166 (45%), Positives = 84/166 (50%), Gaps = 33/166 (19%)

Query: 391 GGDFRGRGYGGERGYRGRGGRGGDRGGY-------GGDRSGGGY--GGDRSSG---GGYS 438
           GG  +G G GG  GY   GGRGG RG         GG   GGGY  GG R SG   GGY 
Sbjct: 352 GGHEQGGGRGGRGGY-DHGGRGGGRGNKHQGGWTDGGSGGGGGYQDGGYRDSGFQPGGYH 410

Query: 439 GDRS-----GGGYGGDRSGGGYGGD--RGGGYGGD---RGGGYGGDRGGGYGGDRGGYGG 488
           G  S     GGGYGG ++   Y G   +GGGY  D   + GG+ GDRGGG GG RGG GG
Sbjct: 411 GGHSSGGYQGGGYGGFQTSSSYTGSGYQGGGYQQDNRYQDGGHHGDRGGGRGG-RGGRGG 469

Query: 489 DRGG--GYGGDRGGYGGDRGGYGGD------RGGYGGDRGGYGGDR 526
            RGG  G GG  GG G      GG        GGY  +  G+G  R
Sbjct: 470 -RGGRAGQGGGWGGRGSQNYHQGGQFEQHFQHGGYQYNHSGFGQGR 514



 Score = 93.2 bits (230), Expect = 6e-19
 Identities = 69/147 (46%), Positives = 73/147 (49%), Gaps = 30/147 (20%)

Query: 457 GDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGY--GGDRGG 514
           G RGGG GG     YGG  G   GG RGG GG   GG GG RG     +GG+  GG  GG
Sbjct: 334 GGRGGGRGGYEHSSYGGRGGHEQGGGRGGRGGYDHGGRGGGRGNK--HQGGWTDGGSGGG 391

Query: 515 YGGDRGGY-----------GGDRSRGGYGGDRGG--------GSGYGGDRSGGYGGDR-- 553
            G   GGY           GG  S G  GG  GG        GSGY G   GGY  D   
Sbjct: 392 GGYQDGGYRDSGFQPGGYHGGHSSGGYQGGGYGGFQTSSSYTGSGYQG---GGYQQDNRY 448

Query: 554 SGGGYGGDRGGGYGGDRGGYGGKMGGR 580
             GG+ GDRGGG GG RGG GG+ GGR
Sbjct: 449 QDGGHHGDRGGGRGG-RGGRGGR-GGR 473



 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 71/260 (27%), Positives = 86/260 (33%), Gaps = 76/260 (29%)

Query: 192 KDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDADSESDNSDNNTIFVQGLGEGVSTDQVG 251
           +DG    TG  GG RGG++    H  YG R   +              G G G       
Sbjct: 326 QDGPQQQTGGRGGGRGGYE----HSSYGGRGGHEQGGGRGGRGGYDHGGRGGG------- 374

Query: 252 EFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATVSFDDPPSAKAAIDWFDGKEFHGN 311
                    + NK  G      +TD  +G   G     + D                   
Sbjct: 375 ---------RGNKHQGG-----WTDGGSGGGGGYQDGGYRD------------------- 401

Query: 312 IIKVSFATRRPEFMRGGGSGGGRRGRGGYRGRGGFQGRGGDPKSGDWVCPNPSCGNMNFA 371
                 +  +P    GG S GG +G GGY   GGFQ       SG               
Sbjct: 402 ------SGFQPGGYHGGHSSGGYQG-GGY---GGFQTSSSYTGSG--------------Y 437

Query: 372 RRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRS----GGGY 427
           +     Q N  R +D    G   RG G GG  G  GRGGR G  GG+GG  S     GG 
Sbjct: 438 QGGGYQQDN--RYQDGGHHGD--RGGGRGGRGGRGGRGGRAGQGGGWGGRGSQNYHQGGQ 493

Query: 428 GGDRSSGGGYSGDRSGGGYG 447
                  GGY  + SG G G
Sbjct: 494 FEQHFQHGGYQYNHSGFGQG 513



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 33/74 (44%), Positives = 35/74 (47%), Gaps = 10/74 (13%)

Query: 513 GGYGGDRGGYGGDRSRGGYGGDRGGGSGYGGDRS--GGYGGDRSGGGYGGDRGGGY--GG 568
           GG GG RGGY        YGG   GG   GG R   GGY     GGG G    GG+  GG
Sbjct: 334 GGRGGGRGGY----EHSSYGGR--GGHEQGGGRGGRGGYDHGGRGGGRGNKHQGGWTDGG 387

Query: 569 DRGGYGGKMGGRND 582
             GG G + GG  D
Sbjct: 388 SGGGGGYQDGGYRD 401



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 60/210 (28%), Positives = 76/210 (36%), Gaps = 53/210 (25%)

Query: 9   QSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQSQSGYSQSYG 68
           Q G +QQ+       G +G G+    +S YG       G    G   Y     G     G
Sbjct: 326 QDGPQQQT-------GGRGGGRGGYEHSSYGGRGGHEQGGGRGGRGGYDHGGRG-----G 373

Query: 69  GYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQQSGYDQHQGS 128
           G  N+ Q  ++               SG  GG        D G +DS  Q  GY  H G 
Sbjct: 374 GRGNKHQGGWTDG------------GSGGGGG------YQDGGYRDSGFQPGGY--HGG- 412

Query: 129 YDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSRYGEDNR----GYGGSQGGG 184
               S+   Q   Y   Q S       Y             Y +DNR    G+ G +GGG
Sbjct: 413 ---HSSGGYQGGGYGGFQTSSSYTGSGYQG---------GGYQQDNRYQDGGHHGDRGGG 460

Query: 185 R-GRGGYDKDGRGPMTGSSGGDRG-GFKNF 212
           R GRGG  + GRG   G  GG  G G +N+
Sbjct: 461 RGGRGG--RGGRGGRAGQGGGWGGRGSQNY 488



 Score = 43.1 bits (100), Expect = 7e-04
 Identities = 44/173 (25%), Positives = 62/173 (35%), Gaps = 35/173 (20%)

Query: 68  GGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQ------QSG 121
           GG  N+ +    + P   + Q    + +G +GG    Y+   YG +  ++Q      + G
Sbjct: 306 GGRPNEIEPPPPEMPPWQKRQDGPQQQTGGRGGGRGGYEHSSYGGRGGHEQGGGRGGRGG 365

Query: 122 YD----------QHQGSY-DEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSRY 170
           YD          +HQG + D  S     +         +     +  H         S  
Sbjct: 366 YDHGGRGGGRGNKHQGGWTDGGSGGGGGYQDGGYRDSGFQPGGYHGGH---------SSG 416

Query: 171 GEDNRGYGGSQ------GGGRGRGGYDKDGR---GPMTGSSGGDRGGFKNFGG 214
           G    GYGG Q      G G   GGY +D R   G   G  GG RGG    GG
Sbjct: 417 GYQGGGYGGFQTSSSYTGSGYQGGGYQQDNRYQDGGHHGDRGGGRGGRGGRGG 469



 Score = 40.4 bits (93), Expect = 0.005
 Identities = 43/155 (27%), Positives = 56/155 (36%), Gaps = 27/155 (17%)

Query: 2   SDSGSYGQSGGEQQSYSTYG-NPGSQGYGQASQSYSGYGQTTDSSYG--QNYSGYSSYGQ 58
           +D GS G  G +   Y   G  PG    G +S  Y G G      YG  Q  S Y+  G 
Sbjct: 384 TDGGSGGGGGYQDGGYRDSGFQPGGYHGGHSSGGYQGGG------YGGFQTSSSYTGSGY 437

Query: 59  SQSGYSQSYGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQ 118
              GY Q     +N+ Q        +  G +      G +GGRA        GQ   +  
Sbjct: 438 QGGGYQQ-----DNRYQDGGHHG--DRGGGRGGRGGRGGRGGRA--------GQGGGWGG 482

Query: 119 QSGYDQHQGSYDEQSNYDQQHDSYSQNQQSYHSQR 153
           +   + HQG   EQ     QH  Y  N   +   R
Sbjct: 483 RGSQNYHQGGQFEQ---HFQHGGYQYNHSGFGQGR 514



 Score = 38.1 bits (87), Expect = 0.023
 Identities = 29/89 (32%), Positives = 39/89 (43%), Gaps = 3/89 (3%)

Query: 131 EQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSRYGEDNRGYGGSQGGGRGRGGY 190
           E   + ++ D   Q        R  Y H +   R    + G    G GG   GGRG G  
Sbjct: 318 EMPPWQKRQDGPQQQTGGRGGGRGGYEHSSYGGRGGHEQ-GGGRGGRGGYDHGGRGGGRG 376

Query: 191 DKDGRGPMTGSSGGDRGGFKNFGGHRDYG 219
           +K   G   G SGG  GG+++ GG+RD G
Sbjct: 377 NKHQGGWTDGGSGGG-GGYQD-GGYRDSG 403



 Score = 32.3 bits (72), Expect = 1.3
 Identities = 21/45 (46%), Positives = 24/45 (53%), Gaps = 7/45 (15%)

Query: 550 GGDRSGGGYGGDRGG----GYGGDRGGY--GGKMGGRNDYRNDQR 588
           G  +  GG GG RGG     YGG RGG+  GG  GGR  Y +  R
Sbjct: 328 GPQQQTGGRGGGRGGYEHSSYGG-RGGHEQGGGRGGRGGYDHGGR 371


>gi|109148552 keratin 3 [Homo sapiens]
          Length = 628

 Score =  107 bits (268), Expect = 2e-23
 Identities = 73/167 (43%), Positives = 85/167 (50%), Gaps = 18/167 (10%)

Query: 412 GGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRGGGY 471
           GG   G+ G RS    G  R S   +SG   GG YG     GG+G       GG++    
Sbjct: 10  GGGSQGFSG-RSAVVSGSSRMSCVAHSGGAGGGAYGFRSGAGGFGSRSLYNLGGNKSISI 68

Query: 472 ----GGDRGGGYGGDR------GGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGG 521
               GG R GG+GG R      GGYGG  G GYGG   G+GG  GG  G  GG+GG  GG
Sbjct: 69  SVAAGGSRAGGFGGGRSSCAFAGGYGGGFGSGYGG---GFGGGFGGGRGMGGGFGG-AGG 124

Query: 522 YGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDRGGGYGG 568
           +GG    GG GG  GG  G+GG  SGG+GG  S G  GG   GG+ G
Sbjct: 125 FGGAGGFGGAGG-FGGPGGFGG--SGGFGGPGSLGSPGGFGPGGFPG 168



 Score =  104 bits (259), Expect = 3e-22
 Identities = 75/166 (45%), Positives = 85/166 (51%), Gaps = 38/166 (22%)

Query: 400 GGERGYRGRGG-------------RGGDRGGYGGDRSGGGYGGDRSS---GGGYS----- 438
           GG +G+ GR                GG  GG  G RSG G  G RS    GG  S     
Sbjct: 11  GGSQGFSGRSAVVSGSSRMSCVAHSGGAGGGAYGFRSGAGGFGSRSLYNLGGNKSISISV 70

Query: 439 --GDRSGGGYGGDRSG----GGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGG 492
             G    GG+GG RS     GGYGG  G GYGG  GGG+GG RG G     GG+GG   G
Sbjct: 71  AAGGSRAGGFGGGRSSCAFAGGYGGGFGSGYGGGFGGGFGGGRGMG-----GGFGG--AG 123

Query: 493 GYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGG 538
           G+GG  GG+GG  GG+GG  GG+GG  GG+GG  S G  GG   GG
Sbjct: 124 GFGG-AGGFGG-AGGFGGP-GGFGGS-GGFGGPGSLGSPGGFGPGG 165



 Score = 83.6 bits (205), Expect = 5e-16
 Identities = 70/160 (43%), Positives = 82/160 (51%), Gaps = 33/160 (20%)

Query: 387 SRPSGGDFRGRGYGGERGYRGRGGRGGDRGGY--GGDRS-----------GGGYGGDRSS 433
           SR S     G   GG  G+R   G  G R  Y  GG++S            GG+GG RSS
Sbjct: 27  SRMSCVAHSGGAGGGAYGFRSGAGGFGSRSLYNLGGNKSISISVAAGGSRAGGFGGGRSS 86

Query: 434 ---GGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDR 490
               GGY G   G GYGG   GGG+GG RG   GG    G+GG   GG+GG  GG+GG  
Sbjct: 87  CAFAGGYGGG-FGSGYGGG-FGGGFGGGRG--MGG----GFGG--AGGFGG-AGGFGG-- 133

Query: 491 GGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGG 530
            GG+GG  GG+GG  GG+GG   G  G  GG+G     GG
Sbjct: 134 AGGFGGP-GGFGGS-GGFGGP--GSLGSPGGFGPGGFPGG 169



 Score = 82.0 bits (201), Expect = 1e-15
 Identities = 66/149 (44%), Positives = 75/149 (50%), Gaps = 21/149 (14%)

Query: 442 SGGGYGG--DRSGGGYGGDRGGGY---GGDRGGGYGGDRGGGYGGDRGGY--GGDRGGGY 494
           SGGG  G   RS    G  R       GG  GG YG   G G  G R  Y  GG++    
Sbjct: 9   SGGGSQGFSGRSAVVSGSSRMSCVAHSGGAGGGAYGFRSGAGGFGSRSLYNLGGNKSISI 68

Query: 495 GGDRGGYGGDRGGYGGDR------GGYGGDRG-GYGGDRSRGGYGGDRGGGSGYGGDRSG 547
               GG     GG+GG R      GGYGG  G GYGG    GG+GG RG G G+GG  +G
Sbjct: 69  SVAAGG--SRAGGFGGGRSSCAFAGGYGGGFGSGYGGGFG-GGFGGGRGMGGGFGG--AG 123

Query: 548 GYGGDRSGGGYGGDRG-GGYGGDRGGYGG 575
           G+GG    GG GG  G GG+GG  GG+GG
Sbjct: 124 GFGGAGGFGGAGGFGGPGGFGGS-GGFGG 151



 Score = 79.0 bits (193), Expect = 1e-14
 Identities = 72/195 (36%), Positives = 87/195 (44%), Gaps = 43/195 (22%)

Query: 308 FHGNIIKVSFATRRPEFMRGGGSGGGRRGRGGYRGRGGFQGRGGDPKSGDWVCPNPSCGN 367
           F G    VS ++R       GG+GGG  G     G GGF  R              S  N
Sbjct: 16  FSGRSAVVSGSSRMSCVAHSGGAGGGAYGFRS--GAGGFGSR--------------SLYN 59

Query: 368 MNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRG-RGGRGGDRG-GYGGDRSGG 425
           +   +  S +            + G  R  G+GG R      GG GG  G GYGG   GG
Sbjct: 60  LGGNKSISISV-----------AAGGSRAGGFGGGRSSCAFAGGYGGGFGSGYGGG-FGG 107

Query: 426 GYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGG 485
           G+GG R  GGG+ G    GG+GG    GG+GG   GG+GG   GG+GG   GG+GG  G 
Sbjct: 108 GFGGGRGMGGGFGG---AGGFGG---AGGFGG--AGGFGGP--GGFGG--SGGFGGP-GS 154

Query: 486 YGGDRGGGYGGDRGG 500
            G   G G GG  GG
Sbjct: 155 LGSPGGFGPGGFPGG 169



 Score = 74.7 bits (182), Expect = 2e-13
 Identities = 62/145 (42%), Positives = 70/145 (48%), Gaps = 34/145 (23%)

Query: 451 SGGGYGGDRGGGYGGDRGGGYGGDR------GGGYGGDRGGYGGDRGGGYGGDRGGYGGD 504
           SGGG       G+ G      G  R       GG GG  G YG   G G  G R  Y   
Sbjct: 9   SGGG-----SQGFSGRSAVVSGSSRMSCVAHSGGAGG--GAYGFRSGAGGFGSRSLYN-- 59

Query: 505 RGGYGGDRG-----GYGGDR-GGYGGDRSR----GGYGGDRGGGSGYGGDRSGGYGGDRS 554
               GG++        GG R GG+GG RS     GGYGG  G GSGYGG   GG+GG R 
Sbjct: 60  ---LGGNKSISISVAAGGSRAGGFGGGRSSCAFAGGYGG--GFGSGYGGGFGGGFGGGRG 114

Query: 555 -GGGYGGDRGGGYGGDRGGYGGKMG 578
            GGG+GG   GG+GG  GG+GG  G
Sbjct: 115 MGGGFGG--AGGFGG-AGGFGGAGG 136



 Score = 72.8 bits (177), Expect = 8e-13
 Identities = 39/81 (48%), Positives = 45/81 (55%), Gaps = 3/81 (3%)

Query: 451 SGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGG 510
           S GGYGG  GGG GG  GGG+    G G G  RGG GG  GGG+GG   G+ G   G+G 
Sbjct: 534 SAGGYGGGYGGGMGGGLGGGFSAGGGSGSGFGRGG-GGGIGGGFGGGSSGFSGG-SGFGS 591

Query: 511 DRGG-YGGDRGGYGGDRSRGG 530
             G  YG   GG+    +RGG
Sbjct: 592 ISGARYGVSGGGFSSASNRGG 612



 Score = 66.2 bits (160), Expect = 8e-11
 Identities = 38/91 (41%), Positives = 43/91 (47%), Gaps = 14/91 (15%)

Query: 461 GGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRG 520
           GGYGG  GGG GG  GGG+       GG  G G+G         RGG GG  GG+GG   
Sbjct: 536 GGYGGGYGGGMGGGLGGGFSA-----GGGSGSGFG---------RGGGGGIGGGFGGGSS 581

Query: 521 GYGGDRSRGGYGGDRGGGSGYGGDRSGGYGG 551
           G+ G    G   G R G SG G   +   GG
Sbjct: 582 GFSGGSGFGSISGARYGVSGGGFSSASNRGG 612



 Score = 65.1 bits (157), Expect = 2e-10
 Identities = 40/88 (45%), Positives = 45/88 (51%), Gaps = 11/88 (12%)

Query: 477 GGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRG 536
           GGYGG   GYGG  GGG GG     GG   G+G  RGG GG  GG+GG  S  G+     
Sbjct: 536 GGYGG---GYGGGMGGGLGGGFSAGGGSGSGFG--RGGGGGIGGGFGGGSS--GF----S 584

Query: 537 GGSGYGGDRSGGYGGDRSGGGYGGDRGG 564
           GGSG+G      YG    G     +RGG
Sbjct: 585 GGSGFGSISGARYGVSGGGFSSASNRGG 612



 Score = 64.7 bits (156), Expect = 2e-10
 Identities = 39/87 (44%), Positives = 44/87 (50%), Gaps = 10/87 (11%)

Query: 423 SGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGD 482
           S GGYGG      GY G   GG  GG  +GGG G   G G GG  GGG+GG   G  GG 
Sbjct: 534 SAGGYGG------GYGGGMGGGLGGGFSAGGGSGSGFGRGGGGGIGGGFGGGSSGFSGG- 586

Query: 483 RGGYGGDRGGGYGGDRGGY--GGDRGG 507
             G+G   G  YG   GG+    +RGG
Sbjct: 587 -SGFGSISGARYGVSGGGFSSASNRGG 612



 Score = 63.2 bits (152), Expect = 7e-10
 Identities = 41/84 (48%), Positives = 46/84 (54%), Gaps = 10/84 (11%)

Query: 412 GGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRGG-G 470
           GG  GGYGG   GGG GG  S+GGG     SG G+G    GGG GG  GGG  G  GG G
Sbjct: 536 GGYGGGYGGGM-GGGLGGGFSAGGG-----SGSGFGRG-GGGGIGGGFGGGSSGFSGGSG 588

Query: 471 YGGDRGGGYGGDRGGY--GGDRGG 492
           +G   G  YG   GG+    +RGG
Sbjct: 589 FGSISGARYGVSGGGFSSASNRGG 612



 Score = 62.4 bits (150), Expect = 1e-09
 Identities = 41/110 (37%), Positives = 50/110 (45%), Gaps = 11/110 (10%)

Query: 480 GGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGS 539
           GG   G+ G      G  R       GG GG   G+    GG+G  RS    GG++    
Sbjct: 10  GGGSQGFSGRSAVVSGSSRMSCVAHSGGAGGGAYGFRSGAGGFGS-RSLYNLGGNKSISI 68

Query: 540 GY--GGDRSGGYGGDRS--------GGGYGGDRGGGYGGDRGGYGGKMGG 579
               GG R+GG+GG RS        GGG+G   GGG+GG  GG  G  GG
Sbjct: 69  SVAAGGSRAGGFGGGRSSCAFAGGYGGGFGSGYGGGFGGGFGGGRGMGGG 118



 Score = 60.1 bits (144), Expect = 6e-09
 Identities = 36/78 (46%), Positives = 38/78 (48%), Gaps = 12/78 (15%)

Query: 499 GGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGD---RGGGSGYGGDRSGGYGGDRSG 555
           GGYGG   GYGG  G      GG GG  S GG  G    RGGG G GG   GG  G   G
Sbjct: 536 GGYGG---GYGGGMG------GGLGGGFSAGGGSGSGFGRGGGGGIGGGFGGGSSGFSGG 586

Query: 556 GGYGGDRGGGYGGDRGGY 573
            G+G   G  YG   GG+
Sbjct: 587 SGFGSISGARYGVSGGGF 604



 Score = 56.2 bits (134), Expect = 8e-08
 Identities = 29/67 (43%), Positives = 32/67 (47%)

Query: 513 GGYGGDRGGYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDRGGGYGGDRGG 572
           GGYGG  GG  G    GG+    G GSG+G    GG GG   GG  G   G G+G   G 
Sbjct: 536 GGYGGGYGGGMGGGLGGGFSAGGGSGSGFGRGGGGGIGGGFGGGSSGFSGGSGFGSISGA 595

Query: 573 YGGKMGG 579
             G  GG
Sbjct: 596 RYGVSGG 602



 Score = 54.3 bits (129), Expect = 3e-07
 Identities = 33/81 (40%), Positives = 35/81 (43%), Gaps = 5/81 (6%)

Query: 398 GYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGG 457
           GYGG  G    GG GG     GG  SG G GG    GGG+     GGG  G   G G+G 
Sbjct: 537 GYGGGYGGGMGGGLGGGFSAGGGSGSGFGRGGGGGIGGGF-----GGGSSGFSGGSGFGS 591

Query: 458 DRGGGYGGDRGGGYGGDRGGG 478
             G  YG   GG       GG
Sbjct: 592 ISGARYGVSGGGFSSASNRGG 612



 Score = 53.9 bits (128), Expect = 4e-07
 Identities = 35/80 (43%), Positives = 38/80 (47%), Gaps = 6/80 (7%)

Query: 409 GGRGGDRGGYGGDRSGGGY--GGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGD 466
           GG GG  GG  G   GGG+  GG   SG G  G   GGG GG   GG  G   G G+G  
Sbjct: 536 GGYGGGYGGGMGGGLGGGFSAGGGSGSGFGRGG---GGGIGGGFGGGSSGFSGGSGFGSI 592

Query: 467 RGGGYGGDRGG-GYGGDRGG 485
            G  YG   GG     +RGG
Sbjct: 593 SGARYGVSGGGFSSASNRGG 612



 Score = 46.2 bits (108), Expect = 8e-05
 Identities = 30/73 (41%), Positives = 33/73 (45%), Gaps = 2/73 (2%)

Query: 391 GGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRS--SGGGYSGDRSGGGYGG 448
           GG   G G G   G+   GG G   G  GG   GGG+GG  S  SGG   G  SG  YG 
Sbjct: 540 GGYGGGMGGGLGGGFSAGGGSGSGFGRGGGGGIGGGFGGGSSGFSGGSGFGSISGARYGV 599

Query: 449 DRSGGGYGGDRGG 461
              G     +RGG
Sbjct: 600 SGGGFSSASNRGG 612



 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 33/77 (42%), Positives = 34/77 (44%), Gaps = 5/77 (6%)

Query: 396 GRGYGGERGYRGRGG--RGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGG 453
           G GYGG  G    GG   GG  G   G   GGG GG    GGG SG   G G+ G  SG 
Sbjct: 539 GGGYGGGMGGGLGGGFSAGGGSGSGFGRGGGGGIGG--GFGGGSSGFSGGSGF-GSISGA 595

Query: 454 GYGGDRGGGYGGDRGGG 470
            YG   GG       GG
Sbjct: 596 RYGVSGGGFSSASNRGG 612



 Score = 36.6 bits (83), Expect = 0.067
 Identities = 21/47 (44%), Positives = 22/47 (46%), Gaps = 6/47 (12%)

Query: 539 SGYGGDRSGGYGGDRSGG-----GYGGDRGGGYG-GDRGGYGGKMGG 579
           S   G   GGYGG   GG       GG  G G+G G  GG GG  GG
Sbjct: 532 SASAGGYGGGYGGGMGGGLGGGFSAGGGSGSGFGRGGGGGIGGGFGG 578



 Score = 34.7 bits (78), Expect = 0.25
 Identities = 21/51 (41%), Positives = 23/51 (45%), Gaps = 8/51 (15%)

Query: 176 GYGGSQGGGRGRGGYDKD-------GRGPMTGSSGGDRGGFKNFGGHRDYG 219
           GYGG  GGG G GG+          GRG   G  GG  GG   F G   +G
Sbjct: 541 GYGGGMGGGLG-GGFSAGGGSGSGFGRGGGGGIGGGFGGGSSGFSGGSGFG 590



 Score = 33.5 bits (75), Expect = 0.56
 Identities = 24/84 (28%), Positives = 36/84 (42%), Gaps = 12/84 (14%)

Query: 5   GSYGQSGGEQQSYSTYGNPG-SQGYGQASQSYSG---YGQTTDSSYGQNYSGYSSYGQSQ 60
           G +   GG    +   G  G   G+G  S  +SG   +G  + + YG +  G+SS     
Sbjct: 552 GGFSAGGGSGSGFGRGGGGGIGGGFGGGSSGFSGGSGFGSISGARYGVSGGGFSS----- 606

Query: 61  SGYSQSYGGYENQKQSSYSQQPYN 84
              + + GG     QSS S Q Y+
Sbjct: 607 ---ASNRGGSIKFSQSSQSSQRYS 627



 Score = 33.1 bits (74), Expect = 0.74
 Identities = 19/37 (51%), Positives = 20/37 (54%), Gaps = 7/37 (18%)

Query: 546 SGGYGGDRSGGGYGGDRGGGYGG--DRGGYGGKMGGR 580
           +GGYGG     GYGG  GGG GG    GG  G   GR
Sbjct: 535 AGGYGG-----GYGGGMGGGLGGGFSAGGGSGSGFGR 566



 Score = 31.6 bits (70), Expect = 2.1
 Identities = 19/39 (48%), Positives = 20/39 (51%), Gaps = 6/39 (15%)

Query: 176 GYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGG 214
           G+GG  GGGRG GG    G G   G  G   GGF   GG
Sbjct: 104 GFGGGFGGGRGMGG----GFGGAGGFGGA--GGFGGAGG 136



 Score = 31.6 bits (70), Expect = 2.1
 Identities = 34/116 (29%), Positives = 38/116 (32%), Gaps = 35/116 (30%)

Query: 327 GGGSGGGRRGRGGYRGRGGFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPED 386
           GGG GGG  G  G    GGF   GG   SG                              
Sbjct: 539 GGGYGGGMGGGLG----GGFSAGGG---SGSGF--------------------------- 564

Query: 387 SRPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRS 442
            R  GG   G   GG  G+ G  G G   G   G  SGGG+    + GG     +S
Sbjct: 565 GRGGGGGIGGGFGGGSSGFSGGSGFGSISGARYG-VSGGGFSSASNRGGSIKFSQS 619



 Score = 30.4 bits (67), Expect = 4.8
 Identities = 17/39 (43%), Positives = 17/39 (43%)

Query: 176 GYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGG 214
           GYGG  G G G G     G G   G   G  GGF   GG
Sbjct: 92  GYGGGFGSGYGGGFGGGFGGGRGMGGGFGGAGGFGGAGG 130



 Score = 30.0 bits (66), Expect = 6.2
 Identities = 18/44 (40%), Positives = 22/44 (50%), Gaps = 1/44 (2%)

Query: 176 GYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYG 219
           G+GG +G G G GG    G     G +GG  GG   FGG   +G
Sbjct: 108 GFGGGRGMGGGFGGAGGFGGAGGFGGAGG-FGGPGGFGGSGGFG 150



 Score = 29.6 bits (65), Expect = 8.2
 Identities = 18/33 (54%), Positives = 18/33 (54%), Gaps = 1/33 (3%)

Query: 324 FMRGGGSGGGRRGRGGYRGRGGFQGRGGDPKSG 356
           F  GGGSG G  GRGG  G GG  G G    SG
Sbjct: 554 FSAGGGSGSG-FGRGGGGGIGGGFGGGSSGFSG 585


>gi|5803036 heterogeneous nuclear ribonucleoprotein A0 [Homo
           sapiens]
          Length = 305

 Score =  102 bits (253), Expect = 1e-21
 Identities = 61/125 (48%), Positives = 67/125 (53%), Gaps = 7/125 (5%)

Query: 423 SGGGYGGDRSSGGGYSGDRSGGG--YGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYG 480
           SGGG GG RSS GG  G   GGG    G   GGG G +  GGYGG  GGGY    GGG G
Sbjct: 181 SGGGGGGSRSSRGGRGGRGRGGGRDQNGLSKGGGGGYNSYGGYGGGGGGGYNAYGGGGGG 240

Query: 481 GDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGG--YGGDRSRGGYGGDRGGG 538
              G  G D G G+GG  G Y   +  YG  + G GG  GG  +GG  + G Y G  GGG
Sbjct: 241 SSYG--GSDYGNGFGG-FGSYSQHQSSYGPMKSGGGGGGGGSSWGGRSNSGPYRGGYGGG 297

Query: 539 SGYGG 543
            GYGG
Sbjct: 298 GGYGG 302



 Score = 96.3 bits (238), Expect = 7e-20
 Identities = 86/266 (32%), Positives = 111/266 (41%), Gaps = 53/266 (19%)

Query: 221 RTDADSESDNSDNNTIFVQGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTG 280
           R D+     ++    +FV GL   V+   + E F Q G ++  +        +  DK +G
Sbjct: 85  REDSARPGAHAKVKKLFVGGLKGDVAEGDLIEHFSQFGTVEKAE--------IIADKQSG 136

Query: 281 KPKGEATVSFDDPPSA-KAAIDWFDGKEFHGNIIKVSFATRRPEFMRGGGSGGGRRGRGG 339
           K +G   V F +  +A KAA+  F      G+ ++V  A  + +   GGG GG R  RGG
Sbjct: 137 KKRGFGFVYFQNHDAADKAAVVKFH--PIQGHRVEVKKAVPKEDIYSGGGGGGSRSSRGG 194

Query: 340 Y--RGRGGFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGR 397
              RGRGG + + G  K G         G  N                        + G 
Sbjct: 195 RGGRGRGGGRDQNGLSKGGG--------GGYN-----------------------SYGGY 223

Query: 398 GYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGG 457
           G GG  GY   GG GG    YGG   G G+GG     G YS  +S  G      GGG GG
Sbjct: 224 GGGGGGGYNAYGGGGGG-SSYGGSDYGNGFGGF----GSYSQHQSSYGPMKSGGGGGGGG 278

Query: 458 DRGGG--YGGDRGGGYGGDRGGGYGG 481
              GG    G   GGYGG  GGGYGG
Sbjct: 279 SSWGGRSNSGPYRGGYGG--GGGYGG 302



 Score = 95.5 bits (236), Expect = 1e-19
 Identities = 66/140 (47%), Positives = 73/140 (52%), Gaps = 16/140 (11%)

Query: 389 PSGGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGG 448
           P    + G G GG R    RGGRGG   G G D++G   GG    GGGY+   S GGYGG
Sbjct: 175 PKEDIYSGGGGGGSRS--SRGGRGGRGRGGGRDQNGLSKGG----GGGYN---SYGGYGG 225

Query: 449 DRSGG--GYGGDRGGG-YGG-DRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGD 504
              GG   YGG  GG  YGG D G G+GG   G Y   +  YG  + GG GG  G   G 
Sbjct: 226 GGGGGYNAYGGGGGGSSYGGSDYGNGFGGF--GSYSQHQSSYGPMKSGGGGGGGGSSWGG 283

Query: 505 RGGYGGDRGGYGGDRGGYGG 524
           R   G  RGGYGG  GGYGG
Sbjct: 284 RSNSGPYRGGYGGG-GGYGG 302



 Score = 95.1 bits (235), Expect = 2e-19
 Identities = 66/132 (50%), Positives = 71/132 (53%), Gaps = 15/132 (11%)

Query: 442 SGGGYGGDRSGGGYGGDRGGGYGGDRGG-GYGGDRGGGYGGDRGGYGGDRGGGYGGDRGG 500
           SGGG GG RS  G  G RG G G D+ G   GG  GGGY    GGYGG  GGGY    GG
Sbjct: 181 SGGGGGGSRSSRGGRGGRGRGGGRDQNGLSKGG--GGGY-NSYGGYGGGGGGGYNAYGGG 237

Query: 501 YGGDRGGYGGDRGGYGGDRGGYGG-DRSRGGYGGDRGGGSGYGGDRSGGYGGDRSG---G 556
            GG    YGG    YG   GG+G   + +  YG  + GG G GG  S G G   SG   G
Sbjct: 238 GGG--SSYGG--SDYGNGFGGFGSYSQHQSSYGPMKSGGGGGGGGSSWG-GRSNSGPYRG 292

Query: 557 GYGGDRGGGYGG 568
           GYGG  GGGYGG
Sbjct: 293 GYGG--GGGYGG 302



 Score = 77.4 bits (189), Expect = 3e-14
 Identities = 53/123 (43%), Positives = 58/123 (47%), Gaps = 18/123 (14%)

Query: 471 YGGDRGGGYGGDRGGYGGDRGGGYGGDRGGY----GGDRGGYGGDRGGYGGDRGGYGGDR 526
           Y G  GGG    RGG GG RG G G D+ G     GG    YGG  GG GG    YGG  
Sbjct: 180 YSGGGGGGSRSSRGGRGG-RGRGGGRDQNGLSKGGGGGYNSYGGYGGGGGGGYNAYGGGG 238

Query: 527 SRGGYGGDRGGGSGYGG-----DRSGGYGGDRSGGGYGGDRGGGYGGD------RGGYGG 575
               YGG    G+G+GG          YG  +SGGG GG  G  +GG       RGGYGG
Sbjct: 239 GGSSYGGS-DYGNGFGGFGSYSQHQSSYGPMKSGGG-GGGGGSSWGGRSNSGPYRGGYGG 296

Query: 576 KMG 578
             G
Sbjct: 297 GGG 299



 Score = 73.2 bits (178), Expect = 6e-13
 Identities = 49/111 (44%), Positives = 54/111 (48%), Gaps = 18/111 (16%)

Query: 486 YGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGG-SGYGGD 544
           Y G  GGG    RGG GG   G GG R   G  +GG GG  S GGYGG  GGG + YGG 
Sbjct: 180 YSGGGGGGSRSSRGGRGGR--GRGGGRDQNGLSKGGGGGYNSYGGYGGGGGGGYNAYGGG 237

Query: 545 RSG-GYGGDRSGGGYGGDRGGGY------------GGDRGGYGGKMGGRND 582
             G  YGG   G G+GG   G Y            GG  GG G   GGR++
Sbjct: 238 GGGSSYGGSDYGNGFGG--FGSYSQHQSSYGPMKSGGGGGGGGSSWGGRSN 286



 Score = 65.9 bits (159), Expect = 1e-10
 Identities = 38/68 (55%), Positives = 39/68 (57%), Gaps = 2/68 (2%)

Query: 520 GGYGGDRS-RGGYGG-DRGGGSGYGGDRSGGYGGDRSGGGYGGDRGGGYGGDRGGYGGKM 577
           GG GG RS RGG GG  RGGG    G   GG GG  S GGYGG  GGGY    GG GG  
Sbjct: 183 GGGGGSRSSRGGRGGRGRGGGRDQNGLSKGGGGGYNSYGGYGGGGGGGYNAYGGGGGGSS 242

Query: 578 GGRNDYRN 585
            G +DY N
Sbjct: 243 YGGSDYGN 250



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 39/120 (32%), Positives = 49/120 (40%), Gaps = 23/120 (19%)

Query: 5   GSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQ--NYSGYSSYGQSQSG 62
           G  G+ GG  Q      N  S+G G    SY GYG      Y       G SSYG S   
Sbjct: 196 GGRGRGGGRDQ------NGLSKGGGGGYNSYGGYGGGGGGGYNAYGGGGGGSSYGGSD-- 247

Query: 63  YSQSYGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQQSGY 122
           Y   +GG+      SYSQ    +Q     M+S G  GG   S+     G+ +S   + GY
Sbjct: 248 YGNGFGGF-----GSYSQ----HQSSYGPMKSGGGGGGGGSSWG----GRSNSGPYRGGY 294



 Score = 37.0 bits (84), Expect = 0.051
 Identities = 24/79 (30%), Positives = 32/79 (40%), Gaps = 5/79 (6%)

Query: 142 YSQNQQSYHSQRENYSHHTQDDRRDVSRYGEDNRGYGGSQGGGR-----GRGGYDKDGRG 196
           Y QN  +         H  Q  R +V +       Y G  GGG      GRGG  + G  
Sbjct: 145 YFQNHDAADKAAVVKFHPIQGHRVEVKKAVPKEDIYSGGGGGGSRSSRGGRGGRGRGGGR 204

Query: 197 PMTGSSGGDRGGFKNFGGH 215
              G S G  GG+ ++GG+
Sbjct: 205 DQNGLSKGGGGGYNSYGGY 223



 Score = 33.5 bits (75), Expect = 0.56
 Identities = 26/62 (41%), Positives = 29/62 (46%), Gaps = 13/62 (20%)

Query: 168 SRYGEDNRGYGG-------SQGGGRG---RGGYDKDGRGPMTGSSGGDRGGFKNFGGHRD 217
           SR G   RG GG       S+GGG G    GGY   G G      GG  GG  ++GG  D
Sbjct: 191 SRGGRGGRGRGGGRDQNGLSKGGGGGYNSYGGYGGGGGGGYNAYGGG--GGGSSYGG-SD 247

Query: 218 YG 219
           YG
Sbjct: 248 YG 249



 Score = 32.3 bits (72), Expect = 1.3
 Identities = 51/206 (24%), Positives = 62/206 (30%), Gaps = 81/206 (39%)

Query: 3   DSGSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQSQSG 62
           D  S G  GG + S    G  G +G G+     S  G       G  Y+ Y  YG    G
Sbjct: 178 DIYSGGGGGGSRSSRGGRGGRG-RGGGRDQNGLSKGG-------GGGYNSYGGYGGGGGG 229

Query: 63  YSQSYGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQQSGY 122
              +YGG                             GG   SY   DYG        +G+
Sbjct: 230 GYNAYGG-----------------------------GGGGSSYGGSDYG--------NGF 252

Query: 123 DQHQGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSRYGEDNRGYGGSQG 182
               G +           SYSQ+Q SY   +                      G GGS  
Sbjct: 253 ----GGFG----------SYSQHQSSYGPMKSG-----------------GGGGGGGSSW 281

Query: 183 GGRGRGGYDKDGRGPMTGSSGGDRGG 208
           GGR   G  + G G      GG  GG
Sbjct: 282 GGRSNSGPYRGGYG-----GGGGYGG 302



 Score = 32.3 bits (72), Expect = 1.3
 Identities = 22/68 (32%), Positives = 25/68 (36%), Gaps = 15/68 (22%)

Query: 2   SDSGSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQSQS 61
           S  G  G  GG   +Y         G G    SY G      S YG  + G+ SY Q QS
Sbjct: 219 SYGGYGGGGGGGYNAY---------GGGGGGSSYGG------SDYGNGFGGFGSYSQHQS 263

Query: 62  GYSQSYGG 69
            Y     G
Sbjct: 264 SYGPMKSG 271



 Score = 31.6 bits (70), Expect = 2.1
 Identities = 48/218 (22%), Positives = 76/218 (34%), Gaps = 16/218 (7%)

Query: 17  YSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQSQSGYSQSYGGYENQKQS 76
           + TY N        A+  ++  G T +     +    +  G          GG +     
Sbjct: 52  FVTYSNVEEADAAMAASPHAVDGNTVELKRAVSREDSARPGAHAKVKKLFVGGLKGDVAE 111

Query: 77  SYSQQPYNNQGQQQNMES-SGSQGGRAPSYDQPDYGQQDSYDQQSGYDQH--QGSYDEQS 133
               + ++  G  +  E  +  Q G+   +    +   D+ D+ +    H  QG   E  
Sbjct: 112 GDLIEHFSQFGTVEKAEIIADKQSGKKRGFGFVYFQNHDAADKAAVVKFHPIQGHRVEVK 171

Query: 134 NYDQQHDSYSQN----QQSYHSQRENYSHHTQDDRRDVSRYGEDN-RGYGGSQGGGRGRG 188
               + D YS       +S    R         D+  +S+ G      YGG  GG  G G
Sbjct: 172 KAVPKEDIYSGGGGGGSRSSRGGRGGRGRGGGRDQNGLSKGGGGGYNSYGGYGGG--GGG 229

Query: 189 GYDKDGRGPMTGSSGGDR-----GGFKNFGGHR-DYGP 220
           GY+  G G    S GG       GGF ++  H+  YGP
Sbjct: 230 GYNAYGGGGGGSSYGGSDYGNGFGGFGSYSQHQSSYGP 267



 Score = 31.2 bits (69), Expect = 2.8
 Identities = 22/63 (34%), Positives = 27/63 (42%), Gaps = 14/63 (22%)

Query: 171 GEDNRGYGGSQGG--------GRGRGGYD-----KDGRGPMTGSSGGDRGGFKNFGGHRD 217
           G     YGG  GG        G G GG+      +   GPM  S GG  GG  ++GG  +
Sbjct: 228 GGGYNAYGGGGGGSSYGGSDYGNGFGGFGSYSQHQSSYGPMK-SGGGGGGGGSSWGGRSN 286

Query: 218 YGP 220
            GP
Sbjct: 287 SGP 289


>gi|4504445 heterogeneous nuclear ribonucleoprotein A1 isoform a
           [Homo sapiens]
          Length = 320

 Score =  100 bits (248), Expect = 5e-21
 Identities = 81/291 (27%), Positives = 114/291 (39%), Gaps = 70/291 (24%)

Query: 221 RTDADSESDNSDNNTIFVQGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTG 280
           R D+     +     IFV G+ E      + ++F+Q G I+        +I + TD+ +G
Sbjct: 92  REDSQRPGAHLTVKKIFVGGIKEDTEEHHLRDYFEQYGKIE--------VIEIMTDRGSG 143

Query: 281 KPKGEATVSFDDPPSAKAAIDWFDGKEFH---GNIIKVSFATRRPEFMRGGGSGGGRRGR 337
           K +G A V+FDD  S    +D    +++H   G+  +V  A  + E      S  GR G 
Sbjct: 144 KKRGFAFVTFDDHDS----VDKIVIQKYHTVNGHNCEVRKALSKQEMASASSSQRGRSGS 199

Query: 338 GGYRGRGGFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGR 397
           G +                                                   G  RG 
Sbjct: 200 GNF---------------------------------------------------GGGRGG 208

Query: 398 GYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGG 457
           G+GG   + GRGG    RGG+GG R GGGYGG      G+  D S  G GG  +  G   
Sbjct: 209 GFGGNDNF-GRGGNFSGRGGFGGSRGGGGYGGSGDGYNGFGNDGSNFGGGGSYNDFGNYN 267

Query: 458 DRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRG-GGYGG--DRGGYGGDR 505
           ++   +G  +GG +GG   G YGG    +   R  GGYGG      YG  R
Sbjct: 268 NQSSNFGPMKGGNFGGRSSGPYGGGGQYFAKPRNQGGYGGSSSSSSYGSGR 318



 Score = 92.0 bits (227), Expect = 1e-18
 Identities = 59/139 (42%), Positives = 71/139 (51%), Gaps = 16/139 (11%)

Query: 432 SSGGGYSGDRSGGGYGGDRSGGGYGGD----RGGGYGGDRGGGYGGDR-GGGYGGDRGGY 486
           S+     G    G +GG R GGG+GG+    RGG + G   GG+GG R GGGYGG   GY
Sbjct: 188 SASSSQRGRSGSGNFGGGR-GGGFGGNDNFGRGGNFSG--RGGFGGSRGGGGYGGSGDGY 244

Query: 487 G--GDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSGYGGD 544
              G+ G  +GG  GG   D G Y      +G  +GG  G RS G YG   GGG  +   
Sbjct: 245 NGFGNDGSNFGG--GGSYNDFGNYNNQSSNFGPMKGGNFGGRSSGPYG---GGGQYFAKP 299

Query: 545 RS-GGYGGDRSGGGYGGDR 562
           R+ GGYGG  S   YG  R
Sbjct: 300 RNQGGYGGSSSSSSYGSGR 318



 Score = 92.0 bits (227), Expect = 1e-18
 Identities = 56/135 (41%), Positives = 66/135 (48%), Gaps = 10/135 (7%)

Query: 402 ERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGG 461
           +RG  G G  GG RGG  G     G GG+ S  GG+ G R GGGYGG  SG GY G   G
Sbjct: 193 QRGRSGSGNFGGGRGGGFGGNDNFGRGGNFSGRGGFGGSRGGGGYGG--SGDGYNG--FG 248

Query: 462 GYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGG-DRGGYGGDRGGYGGDRGGYGGDRG 520
             G + GGG   +  G Y      +G  +GG +GG   G YGG     GG       ++G
Sbjct: 249 NDGSNFGGGGSYNDFGNYNNQSSNFGPMKGGNFGGRSSGPYGG-----GGQYFAKPRNQG 303

Query: 521 GYGGDRSRGGYGGDR 535
           GYGG  S   YG  R
Sbjct: 304 GYGGSSSSSSYGSGR 318



 Score = 92.0 bits (227), Expect = 1e-18
 Identities = 58/130 (44%), Positives = 71/130 (54%), Gaps = 22/130 (16%)

Query: 450 RSGGG-YGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGY 508
           RSG G +GG RGGG+GG+   G    RGG + G RGG+GG RGGG      GYGG   GY
Sbjct: 196 RSGSGNFGGGRGGGFGGNDNFG----RGGNFSG-RGGFGGSRGGG------GYGGSGDGY 244

Query: 509 GGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDRGGGYGG 568
            G    +G D   +GG  S   +G      S +G  + G +GG RS G YGG  GG Y  
Sbjct: 245 NG----FGNDGSNFGGGGSYNDFGNYNNQSSNFGPMKGGNFGG-RSSGPYGG--GGQYFA 297

Query: 569 ---DRGGYGG 575
              ++GGYGG
Sbjct: 298 KPRNQGGYGG 307



 Score = 75.1 bits (183), Expect = 2e-13
 Identities = 49/113 (43%), Positives = 59/113 (52%), Gaps = 17/113 (15%)

Query: 464 GGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYG 523
           G    G +GG RGGG+GG+   +G  RGG + G RGG+GG RGG     GGYGG   GY 
Sbjct: 195 GRSGSGNFGGGRGGGFGGN-DNFG--RGGNFSG-RGGFGGSRGG-----GGYGGSGDGYN 245

Query: 524 GDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDRGGGYGG-DRGGYGG 575
           G    G  G + GGG  Y     G Y    S   +G  +GG +GG   G YGG
Sbjct: 246 GF---GNDGSNFGGGGSYND--FGNYNNQSSN--FGPMKGGNFGGRSSGPYGG 291



 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 31/68 (45%), Positives = 38/68 (55%), Gaps = 4/68 (5%)

Query: 520 GGYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDRGG--GYGGDRGGYGGKM 577
           G +GG R  GG+GG+   G G      GG+GG R GGGYGG   G  G+G D   +GG  
Sbjct: 200 GNFGGGRG-GGFGGNDNFGRGGNFSGRGGFGGSRGGGGYGGSGDGYNGFGNDGSNFGGG- 257

Query: 578 GGRNDYRN 585
           G  ND+ N
Sbjct: 258 GSYNDFGN 265



 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 27/58 (46%), Positives = 33/58 (56%), Gaps = 3/58 (5%)

Query: 535 RGGGSGYGGDRSGGYGGDRSGGGYGGDRG-GGYGGDR--GGYGGKMGGRNDYRNDQRN 589
           R G   +GG R GG+GG+ + G  G   G GG+GG R  GGYGG   G N + ND  N
Sbjct: 196 RSGSGNFGGGRGGGFGGNDNFGRGGNFSGRGGFGGSRGGGGYGGSGDGYNGFGNDGSN 253



 Score = 40.0 bits (92), Expect = 0.006
 Identities = 28/108 (25%), Positives = 42/108 (38%), Gaps = 9/108 (8%)

Query: 6   SYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQ--SQSGY 63
           ++G+ G         G+ G  GYG +   Y+G+G       G N+ G  SY    + +  
Sbjct: 215 NFGRGGNFSGRGGFGGSRGGGGYGGSGDGYNGFGND-----GSNFGGGGSYNDFGNYNNQ 269

Query: 64  SQSYGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYG 111
           S ++G  +       S  PY   GQ        +QGG   S     YG
Sbjct: 270 SSNFGPMKGGNFGGRSSGPYGGGGQY--FAKPRNQGGYGGSSSSSSYG 315



 Score = 37.0 bits (84), Expect = 0.051
 Identities = 18/45 (40%), Positives = 22/45 (48%), Gaps = 11/45 (24%)

Query: 546 SGGYGGDRSGGGYGGDRGGGYGGD-----------RGGYGGKMGG 579
           S    G    G +GG RGGG+GG+           RGG+GG  GG
Sbjct: 190 SSSQRGRSGSGNFGGGRGGGFGGNDNFGRGGNFSGRGGFGGSRGG 234



 Score = 35.4 bits (80), Expect = 0.15
 Identities = 32/126 (25%), Positives = 47/126 (37%), Gaps = 12/126 (9%)

Query: 16  SYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQSQ-----SGYSQSYGGY 70
           S S  G  GS  +G       G+G   +   G N+SG   +G S+      G    Y G+
Sbjct: 190 SSSQRGRSGSGNFGGGRGG--GFGGNDNFGRGGNFSGRGGFGGSRGGGGYGGSGDGYNGF 247

Query: 71  ENQKQSSYSQQPYNNQGQQQNMESS--GSQGGRAPSYDQPDYGQQDSYDQQSGYDQHQGS 128
            N   +      YN+ G   N  S+    +GG         YG    Y  +    ++QG 
Sbjct: 248 GNDGSNFGGGGSYNDFGNYNNQSSNFGPMKGGNFGGRSSGPYGGGGQYFAK---PRNQGG 304

Query: 129 YDEQSN 134
           Y   S+
Sbjct: 305 YGGSSS 310



 Score = 33.5 bits (75), Expect = 0.56
 Identities = 23/64 (35%), Positives = 29/64 (45%), Gaps = 7/64 (10%)

Query: 171 GEDNRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGF----KNFGGHRDYGPRTDADS 226
           G DN G GG+     GRGG+     G   G SG    GF     NFGG   Y    + ++
Sbjct: 212 GNDNFGRGGNF---SGRGGFGGSRGGGGYGGSGDGYNGFGNDGSNFGGGGSYNDFGNYNN 268

Query: 227 ESDN 230
           +S N
Sbjct: 269 QSSN 272



 Score = 33.5 bits (75), Expect = 0.56
 Identities = 30/97 (30%), Positives = 39/97 (40%), Gaps = 13/97 (13%)

Query: 5   GSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQSQSGYS 64
           G YG SG     Y+ +GN GS   G  S +  G      S++G    G  ++G   SG  
Sbjct: 235 GGYGGSG---DGYNGFGNDGSNFGGGGSYNDFGNYNNQSSNFGPMKGG--NFGGRSSG-- 287

Query: 65  QSYGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGR 101
             YGG        Y  +P N  G   +  SS    GR
Sbjct: 288 -PYGG-----GGQYFAKPRNQGGYGGSSSSSSYGSGR 318



 Score = 33.1 bits (74), Expect = 0.74
 Identities = 40/127 (31%), Positives = 51/127 (40%), Gaps = 22/127 (17%)

Query: 139 HDSYSQNQ-QSYHSQR-ENYSHHTQDDRRDVSRYGEDNRGYGGSQ--GGGRGRG--GYDK 192
           HDS  +   Q YH+    N        +++++      RG  GS   GGGRG G  G D 
Sbjct: 156 HDSVDKIVIQKYHTVNGHNCEVRKALSKQEMASASSSQRGRSGSGNFGGGRGGGFGGNDN 215

Query: 193 DGRGPM---TGSSGGDRGGFKNFGGHRDYGPRTDADSESDNSDNNTIFVQGLGEGVSTDQ 249
            GRG      G  GG RGG    GG   YG   D  +   N  +N       G G S + 
Sbjct: 216 FGRGGNFSGRGGFGGSRGG----GG---YGGSGDGYNGFGNDGSN------FGGGGSYND 262

Query: 250 VGEFFKQ 256
            G +  Q
Sbjct: 263 FGNYNNQ 269



 Score = 30.8 bits (68), Expect = 3.7
 Identities = 17/49 (34%), Positives = 25/49 (51%), Gaps = 4/49 (8%)

Query: 176 GYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHR----DYGP 220
           G+GGS+GGG   G  D        GS+ G  G + +FG +     ++GP
Sbjct: 227 GFGGSRGGGGYGGSGDGYNGFGNDGSNFGGGGSYNDFGNYNNQSSNFGP 275


>gi|212549553 interleukin enhancer binding factor 3 isoform d [Homo
           sapiens]
          Length = 898

 Score = 99.8 bits (247), Expect = 6e-21
 Identities = 78/232 (33%), Positives = 95/232 (40%), Gaps = 33/232 (14%)

Query: 377 NQCNEPRPEDSRPSGGDFRGRGYGGERGYRG-------RGGRGGDRGGYGGDRSGGGYGG 429
           N+   P     R  GG  RGRG G  RG+ G         G G    GYGG+ +  GY  
Sbjct: 635 NEVPPPPNLRGRGRGGSIRGRGRG--RGFGGANHGGYMNAGAGYGSYGYGGNSATAGY-S 691

Query: 430 DRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGD 489
              S GG+SG+ SGGG GG     GY    G  Y GD    Y       + G +  +GG 
Sbjct: 692 QFYSNGGHSGNASGGGGGGGGGSSGY----GSYYQGD---NYNSPVPPKHAGKKQPHGGQ 744

Query: 490 RGGGYGGDRGGYGGDRGGYG-----------GDRGGYGGDRGGYGGDRSRGGYGGDRGGG 538
           +   YG     + G +  Y            G + GY   +G Y    S    GG  GGG
Sbjct: 745 QKPSYGSGYQSHQGQQQSYNQSPYSNYGPPQGKQKGYNHGQGSYSYSNSYNSPGG--GGG 802

Query: 539 SGYGGDRSGGYGGD--RSGGGYGGDRGGGYG-GDRGGYGGKMGGRNDYRNDQ 587
           S Y  +    Y G   RSGG   G  G  Y  G  GGYGG  GG + Y+  Q
Sbjct: 803 SDYNYESKFNYSGSGGRSGGNSYGSGGASYNPGSHGGYGGGSGGGSSYQGKQ 854



 Score = 67.8 bits (164), Expect = 3e-11
 Identities = 61/222 (27%), Positives = 93/222 (41%), Gaps = 21/222 (9%)

Query: 2   SDSGSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQSQS 61
           ++ G Y  +G    SY   GN  + GY   SQ YS  G + ++S G    G  S     S
Sbjct: 664 ANHGGYMNAGAGYGSYGYGGNSATAGY---SQFYSNGGHSGNASGGGGGGGGGS-----S 715

Query: 62  GYSQSYGG--YENQKQSSYSQQPYNNQGQQQNMESSGSQG--GRAPSYDQPDYGQQDS-Y 116
           GY   Y G  Y +     ++ +   + GQQ+    SG Q   G+  SY+Q  Y       
Sbjct: 716 GYGSYYQGDNYNSPVPPKHAGKKQPHGGQQKPSYGSGYQSHQGQQQSYNQSPYSNYGPPQ 775

Query: 117 DQQSGYDQHQGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSRYGED--- 173
            +Q GY+  QGSY    +Y   ++S      S ++    +++     R   + YG     
Sbjct: 776 GKQKGYNHGQGSY----SYSNSYNSPGGGGGSDYNYESKFNYSGSGGRSGGNSYGSGGAS 831

Query: 174 -NRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGG 214
            N G  G  GGG G G   +  +G  + S+    G  +N+ G
Sbjct: 832 YNPGSHGGYGGGSGGGSSYQGKQGGYSQSNYNSPGSGQNYSG 873



 Score = 60.8 bits (146), Expect = 3e-09
 Identities = 54/191 (28%), Positives = 77/191 (40%), Gaps = 23/191 (12%)

Query: 37  GYGQTTDSSYGQNYSGYSSYGQSQSGYSQSYGGYENQKQSSYSQQPYNNQGQQQNMESSG 96
           G+G      Y    +GY SYG         YGG  N   + YSQ  Y+N G   N  S G
Sbjct: 660 GFGGANHGGYMNAGAGYGSYG---------YGG--NSATAGYSQF-YSNGGHSGN-ASGG 706

Query: 97  SQGGRAPSYDQPDYGQQDSYDQQSGYDQHQGSYDEQSNYDQQHDSYSQNQQSYHSQRENY 156
             GG   S     Y Q D+Y+      +H G   +Q +  QQ  SY    QS+  Q+++Y
Sbjct: 707 GGGGGGGSSGYGSYYQGDNYNSPVP-PKHAGK--KQPHGGQQKPSYGSGYQSHQGQQQSY 763

Query: 157 SHHTQDD------RRDVSRYGEDNRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFK 210
           +     +      ++    +G+ +  Y  S     G GG D +       S  G R G  
Sbjct: 764 NQSPYSNYGPPQGKQKGYNHGQGSYSYSNSYNSPGGGGGSDYNYESKFNYSGSGGRSGGN 823

Query: 211 NFG-GHRDYGP 220
           ++G G   Y P
Sbjct: 824 SYGSGGASYNP 834



 Score = 50.1 bits (118), Expect = 6e-06
 Identities = 47/150 (31%), Positives = 63/150 (42%), Gaps = 14/150 (9%)

Query: 2   SDSGSYGQSGGEQQSY-----STYGNP-GSQ---GYGQASQSYSGYGQTTDSSYGQNYSG 52
           S    Y    G+QQSY     S YG P G Q    +GQ S SYS    +     G +Y+ 
Sbjct: 748 SYGSGYQSHQGQQQSYNQSPYSNYGPPQGKQKGYNHGQGSYSYSNSYNSPGGGGGSDYNY 807

Query: 53  YSSYGQSQSGYSQSYGGYENQKQSSYSQQPYNNQGQQQNMESS--GSQGGRAPS-YDQPD 109
            S +  S SG  +S G       +SY+   +   G      SS  G QGG + S Y+ P 
Sbjct: 808 ESKFNYSGSG-GRSGGNSYGSGGASYNPGSHGGYGGGSGGGSSYQGKQGGYSQSNYNSPG 866

Query: 110 YGQQDSYDQQSGYDQHQGSYDEQSNYDQQH 139
            GQ  S    S Y   QG Y   +++   +
Sbjct: 867 SGQNYS-GPPSSYQSSQGGYGRNADHSMNY 895



 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 47/189 (24%), Positives = 62/189 (32%), Gaps = 23/189 (12%)

Query: 4   SGSYGQSGGEQQSYSTY---------------GNPGSQGYGQASQSY-SGYGQTTDSSYG 47
           SG  G  GG    Y +Y               G     G GQ   SY SGY         
Sbjct: 704 SGGGGGGGGGSSGYGSYYQGDNYNSPVPPKHAGKKQPHG-GQQKPSYGSGYQSHQGQQQS 762

Query: 48  QNYSGYSSYGQ---SQSGYSQSYGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPS 104
            N S YS+YG     Q GY+   G Y     S+    P    G   N ES  +  G    
Sbjct: 763 YNQSPYSNYGPPQGKQKGYNHGQGSY---SYSNSYNSPGGGGGSDYNYESKFNYSGSGGR 819

Query: 105 YDQPDYGQQDSYDQQSGYDQHQGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDR 164
                YG   +      +  + G     S+Y  +   YSQ+  +     +NYS      +
Sbjct: 820 SGGNSYGSGGASYNPGSHGGYGGGSGGGSSYQGKQGGYSQSNYNSPGSGQNYSGPPSSYQ 879

Query: 165 RDVSRYGED 173
                YG +
Sbjct: 880 SSQGGYGRN 888



 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 70/303 (23%), Positives = 96/303 (31%), Gaps = 59/303 (19%)

Query: 184 GRGRGGYDKDGRGPMTGSSGGDRGGFKNFG-GHRDYGPRTDADSE------SDNSDNNTI 236
           GRGRGG  + GRG   G  G + GG+ N G G+  YG   ++ +       S+   +   
Sbjct: 645 GRGRGGSIR-GRGRGRGFGGANHGGYMNAGAGYGSYGYGGNSATAGYSQFYSNGGHSGNA 703

Query: 237 FVQGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATVSFDDPPSA 296
              G G G  +   G +++           G    +    K  GK +          PS 
Sbjct: 704 SGGGGGGGGGSSGYGSYYQ-----------GDNYNSPVPPKHAGKKQPHGG---QQKPSY 749

Query: 297 KAAIDWFDGKEFHGNIIKVSFATRRPEFMRGGGSGGGRRGRGGYRGRGGFQGRGGDPKSG 356
            +      G++   N  +  ++   P     G   G   G+G Y     +   GG     
Sbjct: 750 GSGYQSHQGQQQSYN--QSPYSNYGPP---QGKQKGYNHGQGSYSYSNSYNSPGGG---- 800

Query: 357 DWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGRGGRGGDRG 416
                    G  ++   +  N            SGG   G  YG      G     G  G
Sbjct: 801 ---------GGSDYNYESKFNYSG---------SGGRSGGNSYGS----GGASYNPGSHG 838

Query: 417 GYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRG 476
           GYGG   GG      SS  G  G  S   Y    SG  Y G          G G   D  
Sbjct: 839 GYGGGSGGG------SSYQGKQGGYSQSNYNSPGSGQNYSGPPSSYQSSQGGYGRNADHS 892

Query: 477 GGY 479
             Y
Sbjct: 893 MNY 895


>gi|24234750 interleukin enhancer binding factor 3 isoform a [Homo
           sapiens]
          Length = 894

 Score = 99.8 bits (247), Expect = 6e-21
 Identities = 78/232 (33%), Positives = 95/232 (40%), Gaps = 33/232 (14%)

Query: 377 NQCNEPRPEDSRPSGGDFRGRGYGGERGYRG-------RGGRGGDRGGYGGDRSGGGYGG 429
           N+   P     R  GG  RGRG G  RG+ G         G G    GYGG+ +  GY  
Sbjct: 631 NEVPPPPNLRGRGRGGSIRGRGRG--RGFGGANHGGYMNAGAGYGSYGYGGNSATAGY-S 687

Query: 430 DRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGD 489
              S GG+SG+ SGGG GG     GY    G  Y GD    Y       + G +  +GG 
Sbjct: 688 QFYSNGGHSGNASGGGGGGGGGSSGY----GSYYQGD---NYNSPVPPKHAGKKQPHGGQ 740

Query: 490 RGGGYGGDRGGYGGDRGGYG-----------GDRGGYGGDRGGYGGDRSRGGYGGDRGGG 538
           +   YG     + G +  Y            G + GY   +G Y    S    GG  GGG
Sbjct: 741 QKPSYGSGYQSHQGQQQSYNQSPYSNYGPPQGKQKGYNHGQGSYSYSNSYNSPGG--GGG 798

Query: 539 SGYGGDRSGGYGGD--RSGGGYGGDRGGGYG-GDRGGYGGKMGGRNDYRNDQ 587
           S Y  +    Y G   RSGG   G  G  Y  G  GGYGG  GG + Y+  Q
Sbjct: 799 SDYNYESKFNYSGSGGRSGGNSYGSGGASYNPGSHGGYGGGSGGGSSYQGKQ 850



 Score = 67.8 bits (164), Expect = 3e-11
 Identities = 61/222 (27%), Positives = 93/222 (41%), Gaps = 21/222 (9%)

Query: 2   SDSGSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQSQS 61
           ++ G Y  +G    SY   GN  + GY   SQ YS  G + ++S G    G  S     S
Sbjct: 660 ANHGGYMNAGAGYGSYGYGGNSATAGY---SQFYSNGGHSGNASGGGGGGGGGS-----S 711

Query: 62  GYSQSYGG--YENQKQSSYSQQPYNNQGQQQNMESSGSQG--GRAPSYDQPDYGQQDS-Y 116
           GY   Y G  Y +     ++ +   + GQQ+    SG Q   G+  SY+Q  Y       
Sbjct: 712 GYGSYYQGDNYNSPVPPKHAGKKQPHGGQQKPSYGSGYQSHQGQQQSYNQSPYSNYGPPQ 771

Query: 117 DQQSGYDQHQGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSRYGED--- 173
            +Q GY+  QGSY    +Y   ++S      S ++    +++     R   + YG     
Sbjct: 772 GKQKGYNHGQGSY----SYSNSYNSPGGGGGSDYNYESKFNYSGSGGRSGGNSYGSGGAS 827

Query: 174 -NRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGG 214
            N G  G  GGG G G   +  +G  + S+    G  +N+ G
Sbjct: 828 YNPGSHGGYGGGSGGGSSYQGKQGGYSQSNYNSPGSGQNYSG 869



 Score = 60.8 bits (146), Expect = 3e-09
 Identities = 54/191 (28%), Positives = 77/191 (40%), Gaps = 23/191 (12%)

Query: 37  GYGQTTDSSYGQNYSGYSSYGQSQSGYSQSYGGYENQKQSSYSQQPYNNQGQQQNMESSG 96
           G+G      Y    +GY SYG         YGG  N   + YSQ  Y+N G   N  S G
Sbjct: 656 GFGGANHGGYMNAGAGYGSYG---------YGG--NSATAGYSQF-YSNGGHSGN-ASGG 702

Query: 97  SQGGRAPSYDQPDYGQQDSYDQQSGYDQHQGSYDEQSNYDQQHDSYSQNQQSYHSQRENY 156
             GG   S     Y Q D+Y+      +H G   +Q +  QQ  SY    QS+  Q+++Y
Sbjct: 703 GGGGGGGSSGYGSYYQGDNYNSPVP-PKHAGK--KQPHGGQQKPSYGSGYQSHQGQQQSY 759

Query: 157 SHHTQDD------RRDVSRYGEDNRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFK 210
           +     +      ++    +G+ +  Y  S     G GG D +       S  G R G  
Sbjct: 760 NQSPYSNYGPPQGKQKGYNHGQGSYSYSNSYNSPGGGGGSDYNYESKFNYSGSGGRSGGN 819

Query: 211 NFG-GHRDYGP 220
           ++G G   Y P
Sbjct: 820 SYGSGGASYNP 830



 Score = 50.1 bits (118), Expect = 6e-06
 Identities = 47/150 (31%), Positives = 63/150 (42%), Gaps = 14/150 (9%)

Query: 2   SDSGSYGQSGGEQQSY-----STYGNP-GSQ---GYGQASQSYSGYGQTTDSSYGQNYSG 52
           S    Y    G+QQSY     S YG P G Q    +GQ S SYS    +     G +Y+ 
Sbjct: 744 SYGSGYQSHQGQQQSYNQSPYSNYGPPQGKQKGYNHGQGSYSYSNSYNSPGGGGGSDYNY 803

Query: 53  YSSYGQSQSGYSQSYGGYENQKQSSYSQQPYNNQGQQQNMESS--GSQGGRAPS-YDQPD 109
            S +  S SG  +S G       +SY+   +   G      SS  G QGG + S Y+ P 
Sbjct: 804 ESKFNYSGSG-GRSGGNSYGSGGASYNPGSHGGYGGGSGGGSSYQGKQGGYSQSNYNSPG 862

Query: 110 YGQQDSYDQQSGYDQHQGSYDEQSNYDQQH 139
            GQ  S    S Y   QG Y   +++   +
Sbjct: 863 SGQNYS-GPPSSYQSSQGGYGRNADHSMNY 891



 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 47/189 (24%), Positives = 62/189 (32%), Gaps = 23/189 (12%)

Query: 4   SGSYGQSGGEQQSYSTY---------------GNPGSQGYGQASQSY-SGYGQTTDSSYG 47
           SG  G  GG    Y +Y               G     G GQ   SY SGY         
Sbjct: 700 SGGGGGGGGGSSGYGSYYQGDNYNSPVPPKHAGKKQPHG-GQQKPSYGSGYQSHQGQQQS 758

Query: 48  QNYSGYSSYGQ---SQSGYSQSYGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPS 104
            N S YS+YG     Q GY+   G Y     S+    P    G   N ES  +  G    
Sbjct: 759 YNQSPYSNYGPPQGKQKGYNHGQGSY---SYSNSYNSPGGGGGSDYNYESKFNYSGSGGR 815

Query: 105 YDQPDYGQQDSYDQQSGYDQHQGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDR 164
                YG   +      +  + G     S+Y  +   YSQ+  +     +NYS      +
Sbjct: 816 SGGNSYGSGGASYNPGSHGGYGGGSGGGSSYQGKQGGYSQSNYNSPGSGQNYSGPPSSYQ 875

Query: 165 RDVSRYGED 173
                YG +
Sbjct: 876 SSQGGYGRN 884



 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 70/303 (23%), Positives = 96/303 (31%), Gaps = 59/303 (19%)

Query: 184 GRGRGGYDKDGRGPMTGSSGGDRGGFKNFG-GHRDYGPRTDADSE------SDNSDNNTI 236
           GRGRGG  + GRG   G  G + GG+ N G G+  YG   ++ +       S+   +   
Sbjct: 641 GRGRGGSIR-GRGRGRGFGGANHGGYMNAGAGYGSYGYGGNSATAGYSQFYSNGGHSGNA 699

Query: 237 FVQGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATVSFDDPPSA 296
              G G G  +   G +++           G    +    K  GK +          PS 
Sbjct: 700 SGGGGGGGGGSSGYGSYYQ-----------GDNYNSPVPPKHAGKKQPHGG---QQKPSY 745

Query: 297 KAAIDWFDGKEFHGNIIKVSFATRRPEFMRGGGSGGGRRGRGGYRGRGGFQGRGGDPKSG 356
            +      G++   N  +  ++   P     G   G   G+G Y     +   GG     
Sbjct: 746 GSGYQSHQGQQQSYN--QSPYSNYGPP---QGKQKGYNHGQGSYSYSNSYNSPGGG---- 796

Query: 357 DWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGRGGRGGDRG 416
                    G  ++   +  N            SGG   G  YG      G     G  G
Sbjct: 797 ---------GGSDYNYESKFNYSG---------SGGRSGGNSYGS----GGASYNPGSHG 834

Query: 417 GYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRG 476
           GYGG   GG      SS  G  G  S   Y    SG  Y G          G G   D  
Sbjct: 835 GYGGGSGGG------SSYQGKQGGYSQSNYNSPGSGQNYSGPPSSYQSSQGGYGRNADHS 888

Query: 477 GGY 479
             Y
Sbjct: 889 MNY 891


>gi|242117971 RNA binding motif protein, X-linked-like 1 [Homo
           sapiens]
          Length = 390

 Score = 98.6 bits (244), Expect = 1e-20
 Identities = 124/395 (31%), Positives = 144/395 (36%), Gaps = 62/395 (15%)

Query: 245 VSTDQVGEFFKQIGIIKTNKKTGKPMINLY---------TDKDTGKPKGEATVSFDDPPS 295
           V  D+ G+ F      +TN+K  + +   Y          D++T K +G A V+F+ P  
Sbjct: 2   VEADRPGKLFIGGLNTETNEKALETVFGKYGRIVEVLLIKDRETNKSRGFAFVTFESPAD 61

Query: 296 AKAAIDWFDGKEFHGNIIKVSFATRRPEFMRG-GGSGGGRRGRGGYR----GRGGFQGRG 350
           AK A    +GK   G  IKV  AT +P F RG  G     R RG  R    GRGG  G  
Sbjct: 62  AKDAARDMNGKSLDGKAIKVEQAT-KPSFERGRHGPPPPPRSRGPPRGFGAGRGGSGGTR 120

Query: 351 GDPKSGDWVCPNPSCGNMNFA--------RRNSCNQCNEPRPEDSRPSGGDFRGRGYGGE 402
           G P  G  +       N N +        +R    +   P P+ S PSG      G GG 
Sbjct: 121 GPPSRGGHMDDGGYSMNFNMSSSRGPLPVKRGPPPRSGGPSPKRSAPSGLVRSSSGMGGR 180

Query: 403 RGY-RGRGGRGGD---------RGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYG---GD 449
               RGR   GG          R  Y   R  G    D  S   Y   R    Y     D
Sbjct: 181 APLSRGRDSYGGPPRREPLPSRRDVYLSPRDDGYSTKDSYSSRDYPSSRDTRDYAPPPRD 240

Query: 450 RSGGGYGGDR------GGGYGGDRGGGYGGDR-------GGGYGGDRGGYGGDRGGGY-G 495
            +   YG           GY GDR  GYG DR       GG Y      YG  R      
Sbjct: 241 YTYRDYGHSSSRDDYPSRGY-GDR-DGYGRDRDYSDHPSGGSYRDSYESYGNSRSAPLTR 298

Query: 496 GDRGGYGGDR--GGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSGYGGDRS--GGYGG 551
           G    YGG      Y   R GYGG R  Y   RS      DR G    G   S   GY  
Sbjct: 299 GPPPSYGGSSRYDDYSSSRDGYGGSRDSYSSSRSDLYSSCDRVGRQERGLPPSVERGYPS 358

Query: 552 DR---SGGGYGGDRGGGYGGDRGGYGGKMGGRNDY 583
            R   S    G  RG G GG R   G   GGR+ Y
Sbjct: 359 SRDSYSSSSRGAPRGAGPGGSRSDRG---GGRSRY 390



 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 52/199 (26%), Positives = 69/199 (34%), Gaps = 29/199 (14%)

Query: 20  YGNPGSQGYGQ----ASQSYSGYGQTTDSSYGQNYSGYSSYGQSQSGYSQSYGGYENQKQ 75
           Y +P   GY      +S+ Y     T D +       Y  YG S S       GY ++  
Sbjct: 206 YLSPRDDGYSTKDSYSSRDYPSSRDTRDYAPPPRDYTYRDYGHSSSRDDYPSRGYGDR-- 263

Query: 76  SSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQQSGYDQHQGSYDEQSNY 135
                   +  G+ ++     S G    SY+   YG   S     G      SY   S Y
Sbjct: 264 --------DGYGRDRDYSDHPSGGSYRDSYES--YGNSRSAPLTRGPPP---SYGGSSRY 310

Query: 136 DQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSRYGEDNRGYGGS--QGGGRGRGGYDKD 193
           D     YS ++  Y   R++YS    D      R G   RG   S  +G    R  Y   
Sbjct: 311 DD----YSSSRDGYGGSRDSYSSSRSDLYSSCDRVGRQERGLPPSVERGYPSSRDSYSSS 366

Query: 194 GRGPMTGSSGG----DRGG 208
            RG   G+  G    DRGG
Sbjct: 367 SRGAPRGAGPGGSRSDRGG 385



 Score = 35.8 bits (81), Expect = 0.11
 Identities = 77/344 (22%), Positives = 110/344 (31%), Gaps = 90/344 (26%)

Query: 24  GSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQS--QSGYSQSYGGYENQKQSSYSQQ 81
           G  G G      S  G   D  Y  N++  SS G    + G     GG  + K+S+ S  
Sbjct: 112 GRGGSGGTRGPPSRGGHMDDGGYSMNFNMSSSRGPLPVKRGPPPRSGG-PSPKRSAPSGL 170

Query: 82  PYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQQSGYDQHQGSYDEQSNYDQQHDS 141
                     + SS   GGRAP         +DSY          G    +     + D 
Sbjct: 171 ----------VRSSSGMGGRAPLSRG-----RDSY----------GGPPRREPLPSRRDV 205

Query: 142 YSQNQQSYHSQRENYSHHTQDDRRDVSRYGEDNR-------GYGGSQGGGRGRGGYDKDG 194
           Y   +   +S +++YS       RD   Y    R       G+  S+     RG  D+DG
Sbjct: 206 YLSPRDDGYSTKDSYSSRDYPSSRDTRDYAPPPRDYTYRDYGHSSSRDDYPSRGYGDRDG 265

Query: 195 RGPMTG-----SSGGDRGGFKNFGGHR----------DYGPRTDADSESDNSDNNTIFVQ 239
            G         S G  R  ++++G  R           YG  +  D  S + D       
Sbjct: 266 YGRDRDYSDHPSGGSYRDSYESYGNSRSAPLTRGPPPSYGGSSRYDDYSSSRD------- 318

Query: 240 GLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATVSFDDPPSAKAA 299
             G G S D       +  +  +  + G+    L    + G P    + S     S++ A
Sbjct: 319 --GYGGSRDSYSS--SRSDLYSSCDRVGRQERGLPPSVERGYPSSRDSYS----SSSRGA 370

Query: 300 IDWFDGKEFHGNIIKVSFATRRPEFMRGGGSGGGRRGRGGYRGR 343
                                     RG G GG R  RGG R R
Sbjct: 371 -------------------------PRGAGPGGSRSDRGGGRSR 389


>gi|21361809 RNA binding motif protein, X-linked-like 1 [Homo
           sapiens]
          Length = 390

 Score = 98.6 bits (244), Expect = 1e-20
 Identities = 124/395 (31%), Positives = 144/395 (36%), Gaps = 62/395 (15%)

Query: 245 VSTDQVGEFFKQIGIIKTNKKTGKPMINLY---------TDKDTGKPKGEATVSFDDPPS 295
           V  D+ G+ F      +TN+K  + +   Y          D++T K +G A V+F+ P  
Sbjct: 2   VEADRPGKLFIGGLNTETNEKALETVFGKYGRIVEVLLIKDRETNKSRGFAFVTFESPAD 61

Query: 296 AKAAIDWFDGKEFHGNIIKVSFATRRPEFMRG-GGSGGGRRGRGGYR----GRGGFQGRG 350
           AK A    +GK   G  IKV  AT +P F RG  G     R RG  R    GRGG  G  
Sbjct: 62  AKDAARDMNGKSLDGKAIKVEQAT-KPSFERGRHGPPPPPRSRGPPRGFGAGRGGSGGTR 120

Query: 351 GDPKSGDWVCPNPSCGNMNFA--------RRNSCNQCNEPRPEDSRPSGGDFRGRGYGGE 402
           G P  G  +       N N +        +R    +   P P+ S PSG      G GG 
Sbjct: 121 GPPSRGGHMDDGGYSMNFNMSSSRGPLPVKRGPPPRSGGPSPKRSAPSGLVRSSSGMGGR 180

Query: 403 RGY-RGRGGRGGD---------RGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYG---GD 449
               RGR   GG          R  Y   R  G    D  S   Y   R    Y     D
Sbjct: 181 APLSRGRDSYGGPPRREPLPSRRDVYLSPRDDGYSTKDSYSSRDYPSSRDTRDYAPPPRD 240

Query: 450 RSGGGYGGDR------GGGYGGDRGGGYGGDR-------GGGYGGDRGGYGGDRGGGY-G 495
            +   YG           GY GDR  GYG DR       GG Y      YG  R      
Sbjct: 241 YTYRDYGHSSSRDDYPSRGY-GDR-DGYGRDRDYSDHPSGGSYRDSYESYGNSRSAPLTR 298

Query: 496 GDRGGYGGDR--GGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSGYGGDRS--GGYGG 551
           G    YGG      Y   R GYGG R  Y   RS      DR G    G   S   GY  
Sbjct: 299 GPPPSYGGSSRYDDYSSSRDGYGGSRDSYSSSRSDLYSSCDRVGRQERGLPPSVERGYPS 358

Query: 552 DR---SGGGYGGDRGGGYGGDRGGYGGKMGGRNDY 583
            R   S    G  RG G GG R   G   GGR+ Y
Sbjct: 359 SRDSYSSSSRGAPRGAGPGGSRSDRG---GGRSRY 390



 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 52/199 (26%), Positives = 69/199 (34%), Gaps = 29/199 (14%)

Query: 20  YGNPGSQGYGQ----ASQSYSGYGQTTDSSYGQNYSGYSSYGQSQSGYSQSYGGYENQKQ 75
           Y +P   GY      +S+ Y     T D +       Y  YG S S       GY ++  
Sbjct: 206 YLSPRDDGYSTKDSYSSRDYPSSRDTRDYAPPPRDYTYRDYGHSSSRDDYPSRGYGDR-- 263

Query: 76  SSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQQSGYDQHQGSYDEQSNY 135
                   +  G+ ++     S G    SY+   YG   S     G      SY   S Y
Sbjct: 264 --------DGYGRDRDYSDHPSGGSYRDSYES--YGNSRSAPLTRGPPP---SYGGSSRY 310

Query: 136 DQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSRYGEDNRGYGGS--QGGGRGRGGYDKD 193
           D     YS ++  Y   R++YS    D      R G   RG   S  +G    R  Y   
Sbjct: 311 DD----YSSSRDGYGGSRDSYSSSRSDLYSSCDRVGRQERGLPPSVERGYPSSRDSYSSS 366

Query: 194 GRGPMTGSSGG----DRGG 208
            RG   G+  G    DRGG
Sbjct: 367 SRGAPRGAGPGGSRSDRGG 385



 Score = 35.8 bits (81), Expect = 0.11
 Identities = 77/344 (22%), Positives = 110/344 (31%), Gaps = 90/344 (26%)

Query: 24  GSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQS--QSGYSQSYGGYENQKQSSYSQQ 81
           G  G G      S  G   D  Y  N++  SS G    + G     GG  + K+S+ S  
Sbjct: 112 GRGGSGGTRGPPSRGGHMDDGGYSMNFNMSSSRGPLPVKRGPPPRSGG-PSPKRSAPSGL 170

Query: 82  PYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQQSGYDQHQGSYDEQSNYDQQHDS 141
                     + SS   GGRAP         +DSY          G    +     + D 
Sbjct: 171 ----------VRSSSGMGGRAPLSRG-----RDSY----------GGPPRREPLPSRRDV 205

Query: 142 YSQNQQSYHSQRENYSHHTQDDRRDVSRYGEDNR-------GYGGSQGGGRGRGGYDKDG 194
           Y   +   +S +++YS       RD   Y    R       G+  S+     RG  D+DG
Sbjct: 206 YLSPRDDGYSTKDSYSSRDYPSSRDTRDYAPPPRDYTYRDYGHSSSRDDYPSRGYGDRDG 265

Query: 195 RGPMTG-----SSGGDRGGFKNFGGHR----------DYGPRTDADSESDNSDNNTIFVQ 239
            G         S G  R  ++++G  R           YG  +  D  S + D       
Sbjct: 266 YGRDRDYSDHPSGGSYRDSYESYGNSRSAPLTRGPPPSYGGSSRYDDYSSSRD------- 318

Query: 240 GLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATVSFDDPPSAKAA 299
             G G S D       +  +  +  + G+    L    + G P    + S     S++ A
Sbjct: 319 --GYGGSRDSYSS--SRSDLYSSCDRVGRQERGLPPSVERGYPSSRDSYS----SSSRGA 370

Query: 300 IDWFDGKEFHGNIIKVSFATRRPEFMRGGGSGGGRRGRGGYRGR 343
                                     RG G GG R  RGG R R
Sbjct: 371 -------------------------PRGAGPGGSRSDRGGGRSR 389


>gi|56699409 RNA binding motif protein, X-linked [Homo sapiens]
          Length = 391

 Score = 97.8 bits (242), Expect = 2e-20
 Identities = 122/402 (30%), Positives = 142/402 (35%), Gaps = 75/402 (18%)

Query: 245 VSTDQVGEFFKQIGIIKTNKKTGKPMINLY---------TDKDTGKPKGEATVSFDDPPS 295
           V  D+ G+ F      +TN+K  + +   Y          D++T K +G A V+F+ P  
Sbjct: 2   VEADRPGKLFIGGLNTETNEKALEAVFGKYGRIVEVLLMKDRETNKSRGFAFVTFESPAD 61

Query: 296 AKAAIDWFDGKEFHGNIIKVSFATRRPEFMRG-----------GGSGGGRRGRGGYRGRG 344
           AK A    +GK   G  IKV  AT +P F  G           G   G R GRGG  G  
Sbjct: 62  AKDAARDMNGKSLDGKAIKVEQAT-KPSFESGRRGPPPPPRSRGPPRGLRGGRGGSGGTR 120

Query: 345 GFQGRGGDPKSGDWVCPNPSCGNMNF----------ARRNSCNQCNEPRPEDSRPSGGDF 394
           G   RGG    G +        +MNF           +R    +   P P+ S PSG   
Sbjct: 121 GPPSRGGHMDDGGY--------SMNFNMSSSRGPLPVKRGPPPRSGGPPPKRSAPSGPVR 172

Query: 395 RGRGYGGERGY-RGRGGRGGD---------RGGYGGDRSGGGYGGDRSSGGGYSGDRSGG 444
              G GG     RGR   GG          R  Y   R  G    D  S   Y   R   
Sbjct: 173 SSSGMGGRAPVSRGRDSYGGPPRREPLPSRRDVYLSPRDDGYSTKDSYSSRDYPSSRDTR 232

Query: 445 GYG---GDRSGGGYGGDRGGGYGGDRG----GGYGGDR-------GGGYGGDRGGYGGDR 490
            Y     D +   YG          RG     GYG DR       GG Y      YG  R
Sbjct: 233 DYAPPPRDYTYRDYGHSSSRDDYPSRGYSDRDGYGRDRDYSDHPSGGSYRDSYESYGNSR 292

Query: 491 GG-GYGGDRGGYGGDR--GGYGGDRGGYGGDRGGYGGDRS-RGGYGGDRGGGS--GYGGD 544
                 G    YGG      Y   R GYGG R  Y   RS     G DR G    G    
Sbjct: 293 SAPPTRGPPPSYGGSSRYDDYSSSRDGYGGSRDSYSSSRSDLYSSGRDRVGRQERGLPPS 352

Query: 545 RSGGYGGDR---SGGGYGGDRGGGYGGDRGGYGGKMGGRNDY 583
              GY   R   S    G  RGGG GG R   G   GGR+ Y
Sbjct: 353 MERGYPPPRDSYSSSSRGAPRGGGRGGSRSDRG---GGRSRY 391



 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 51/199 (25%), Positives = 68/199 (34%), Gaps = 28/199 (14%)

Query: 20  YGNPGSQGYGQ----ASQSYSGYGQTTDSSYGQNYSGYSSYGQSQSGYSQSYGGYENQKQ 75
           Y +P   GY      +S+ Y     T D +       Y  YG S S       GY ++  
Sbjct: 206 YLSPRDDGYSTKDSYSSRDYPSSRDTRDYAPPPRDYTYRDYGHSSSRDDYPSRGYSDR-- 263

Query: 76  SSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQQSGYDQHQGSYDEQSNY 135
                   +  G+ ++     S G    SY+   YG   S     G     G      +Y
Sbjct: 264 --------DGYGRDRDYSDHPSGGSYRDSYES--YGNSRSAPPTRGPPPSYGGSSRYDDY 313

Query: 136 DQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSRYGEDNRGYGGS--QGGGRGRGGYDKD 193
               D Y  ++ SY S R +     +D      R G   RG   S  +G    R  Y   
Sbjct: 314 SSSRDGYGGSRDSYSSSRSDLYSSGRD------RVGRQERGLPPSMERGYPPPRDSYSSS 367

Query: 194 GRG-PMTGSSGG---DRGG 208
            RG P  G  GG   DRGG
Sbjct: 368 SRGAPRGGGRGGSRSDRGG 386



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 68/292 (23%), Positives = 99/292 (33%), Gaps = 60/292 (20%)

Query: 24  GSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQS--QSGYSQSYGGYENQKQSSYSQQ 81
           G  G G      S  G   D  Y  N++  SS G    + G     GG            
Sbjct: 112 GRGGSGGTRGPPSRGGHMDDGGYSMNFNMSSSRGPLPVKRGPPPRSGG-----------P 160

Query: 82  PYNNQGQQQNMESSGSQGGRAP-SYDQPDYG------------------QQDSYDQQSGY 122
           P         + SS   GGRAP S  +  YG                  + D Y  +  Y
Sbjct: 161 PPKRSAPSGPVRSSSGMGGRAPVSRGRDSYGGPPRREPLPSRRDVYLSPRDDGYSTKDSY 220

Query: 123 DQHQ-GSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSRYGEDNRGYGGSQ 181
                 S  +  +Y      Y+     + S R++Y      DR     YG D R Y    
Sbjct: 221 SSRDYPSSRDTRDYAPPPRDYTYRDYGHSSSRDDYPSRGYSDR---DGYGRD-RDYSDHP 276

Query: 182 GGGRGRGGYDKDG--------RGPMTGSSGGDRGGFKNFGGHRD-YGPRTDADSESDNSD 232
            GG  R  Y+  G        RGP     G  R  + ++   RD YG   D    S +S 
Sbjct: 277 SGGSYRDSYESYGNSRSAPPTRGPPPSYGGSSR--YDDYSSSRDGYGGSRD----SYSSS 330

Query: 233 NNTIFVQGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKG 284
            + ++  G       D+VG   ++ G+  + ++   P  + Y+    G P+G
Sbjct: 331 RSDLYSSG------RDRVGR--QERGLPPSMERGYPPPRDSYSSSSRGAPRG 374


>gi|119395750 keratin 1 [Homo sapiens]
          Length = 644

 Score = 96.7 bits (239), Expect = 5e-20
 Identities = 69/164 (42%), Positives = 80/164 (48%), Gaps = 23/164 (14%)

Query: 397 RGYGGERGYRGRGG-RGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGY 455
           R +    GYR  GG   G  G     R        RS GGG      GGG G   +GGG+
Sbjct: 3   RQFSSRSGYRSGGGFSSGSAGIINYQRRTTSSSTRRSGGGGGRFSSCGGGGGSFGAGGGF 62

Query: 456 GGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGY 515
           G       GG +       RGGG G    G+GG    GYGG  GG+GG  GG+G   GG+
Sbjct: 63  GSRSLVNLGGSKSISISVARGGGRGS---GFGG----GYGG--GGFGG--GGFG--GGGF 109

Query: 516 GGDRGGYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYG 559
           GG  GG GG    GG+GG   GG G+GG   GG+GG   GGGYG
Sbjct: 110 GG--GGIGG----GGFGGFGSGGGGFGG---GGFGGGGYGGGYG 144



 Score = 96.3 bits (238), Expect = 7e-20
 Identities = 60/122 (49%), Positives = 60/122 (49%), Gaps = 12/122 (9%)

Query: 451 SGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGG 510
           SGGG  G  GGGYG   GG   G  GG YG   GG GG   G YG     YG   G YG 
Sbjct: 513 SGGGSRGGGGGGYGS--GGSSYGSGGGSYGSGGGGGGGR--GSYGSGGSSYGSGGGSYGS 568

Query: 511 DRGGYGGDRGGYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDRGGGYGGDR 570
             GG GG  G YG   S GGY   RGG  G GG  SGG G   SGGG  G   GG G   
Sbjct: 569 --GGGGGGHGSYGSGSSSGGY---RGGSGGGGGGSSGGRG---SGGGSSGGSIGGRGSSS 620

Query: 571 GG 572
           GG
Sbjct: 621 GG 622



 Score = 92.0 bits (227), Expect = 1e-18
 Identities = 65/137 (47%), Positives = 65/137 (47%), Gaps = 22/137 (16%)

Query: 412 GGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGG-GYGGDRGGG 470
           GG RGG      GGGYG      GG S    GG YG   SGGG GG RG  G GG   G 
Sbjct: 515 GGSRGG-----GGGGYGS-----GGSSYGSGGGSYG---SGGGGGGGRGSYGSGGSSYGS 561

Query: 471 YGGDRG-GGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRG 529
            GG  G GG GG  G YG   G   GG RGG GG  GG  G RG  GG  GG     S G
Sbjct: 562 GGGSYGSGGGGGGHGSYGS--GSSSGGYRGGSGGGGGGSSGGRGSGGGSSGG-----SIG 614

Query: 530 GYGGDRGGGSGYGGDRS 546
           G G   GG    GG  S
Sbjct: 615 GRGSSSGGVKSSGGSSS 631



 Score = 91.7 bits (226), Expect = 2e-18
 Identities = 56/118 (47%), Positives = 57/118 (48%), Gaps = 17/118 (14%)

Query: 464 GGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYG 523
           GG RGGG     GGGYG     YG   GGG  G  GG GG RG YG     YG   G YG
Sbjct: 515 GGSRGGG-----GGGYGSGGSSYGS--GGGSYGSGGGGGGGRGSYGSGGSSYGSGGGSYG 567

Query: 524 GDRSRGGYGGDRGGGSGYG-GDRSGGYGGDRSGGGYGGDRGGGYGGDRGGYGGKMGGR 580
                   GG  GG   YG G  SGGY G   GGG G   G G GG  G  GG +GGR
Sbjct: 568 S-------GGGGGGHGSYGSGSSSGGYRGGSGGGGGGSSGGRGSGG--GSSGGSIGGR 616



 Score = 91.3 bits (225), Expect = 2e-18
 Identities = 59/128 (46%), Positives = 60/128 (46%), Gaps = 14/128 (10%)

Query: 447 GGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRG 506
           GG R GGG G   GG   G  GG YG   GGG GG RG YG   G  YG   G YG   G
Sbjct: 515 GGSRGGGGGGYGSGGSSYGSGGGSYGS--GGGGGGGRGSYGSG-GSSYGSGGGSYGSGGG 571

Query: 507 GYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDRGGGY 566
           G G    G G   GGY     RGG GG  GG SG       G GG  SGG  GG RG   
Sbjct: 572 GGGHGSYGSGSSSGGY-----RGGSGGGGGGSSG-----GRGSGGGSSGGSIGG-RGSSS 620

Query: 567 GGDRGGYG 574
           GG +   G
Sbjct: 621 GGVKSSGG 628



 Score = 90.9 bits (224), Expect = 3e-18
 Identities = 51/112 (45%), Positives = 52/112 (46%), Gaps = 3/112 (2%)

Query: 468 GGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRS 527
           GGG  G  GGGYG     YG   GGG  G  GG GG RG YG     YG   G YG    
Sbjct: 514 GGGSRGGGGGGYGSGGSSYGS--GGGSYGSGGGGGGGRGSYGSGGSSYGSGGGSYGSGGG 571

Query: 528 RGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDRGGGYGGDRGGYGGKMGG 579
            GG+ G  G GS  GG R G  GG     G  G  GG  GG  GG G   GG
Sbjct: 572 GGGH-GSYGSGSSSGGYRGGSGGGGGGSSGGRGSGGGSSGGSIGGRGSSSGG 622



 Score = 89.7 bits (221), Expect = 7e-18
 Identities = 62/144 (43%), Positives = 65/144 (45%), Gaps = 17/144 (11%)

Query: 400 GGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDR 459
           GG RG  G GG G     YG    GG YG    SGGG      GGG G   SGG   G  
Sbjct: 515 GGSRG-GGGGGYGSGGSSYGS--GGGSYG----SGGG-----GGGGRGSYGSGGSSYGSG 562

Query: 460 GGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDR 519
           GG YG   GGG GG    G G   GGY G  GGG GG  GG G   G  GG  GG G   
Sbjct: 563 GGSYGS--GGGGGGHGSYGSGSSSGGYRGGSGGGGGGSSGGRGSGGGSSGGSIGGRGSSS 620

Query: 520 GGYGGDRSRGGYGGDRGGGSGYGG 543
           GG    +S GG    +   + Y G
Sbjct: 621 GGV---KSSGGSSSVKFVSTTYSG 641



 Score = 87.4 bits (215), Expect = 3e-17
 Identities = 70/178 (39%), Positives = 82/178 (46%), Gaps = 46/178 (25%)

Query: 337 RGGYRGRGGFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRG 396
           R GYR  GGF               + S G +N+ RR + +         +R SGG    
Sbjct: 8   RSGYRSGGGFS--------------SGSAGIINYQRRTTSSS--------TRRSGGG--- 42

Query: 397 RGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRS-----SGGGYSGDRSGGGYGGDRS 451
              GG     G GG     GG  G RS    GG +S     + GG  G   GGGYGG   
Sbjct: 43  ---GGRFSSCGGGGGSFGAGGGFGSRSLVNLGGSKSISISVARGGGRGSGFGGGYGGGGF 99

Query: 452 GGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYG 509
           GGG  G  GGG+GG   GG GG   GG+G   GG+G   GGG+GG  GGYG   GGYG
Sbjct: 100 GGG--GFGGGGFGG---GGIGGGGFGGFGSGGGGFG---GGGFGG--GGYG---GGYG 144



 Score = 86.7 bits (213), Expect = 6e-17
 Identities = 60/129 (46%), Positives = 61/129 (47%), Gaps = 17/129 (13%)

Query: 433 SGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRGGGYG----GDRGGGYGGDRGGYGG 488
           SGGG  G   GGGYG   SGG   G  GG YG   GGG G    G  G  YG   G YG 
Sbjct: 513 SGGGSRGG-GGGGYG---SGGSSYGSGGGSYGSGGGGGGGRGSYGSGGSSYGSGGGSYGS 568

Query: 489 DRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSGYGGDRSGG 548
              GG GG  G YG      GG RGG GG  GG  G R  G  GG  GG  G  G  SGG
Sbjct: 569 ---GGGGGGHGSYGSGSSS-GGYRGGSGGGGGGSSGGRGSG--GGSSGGSIGGRGSSSGG 622

Query: 549 YGGDRSGGG 557
               +S GG
Sbjct: 623 V---KSSGG 628



 Score = 85.1 bits (209), Expect = 2e-16
 Identities = 61/126 (48%), Positives = 61/126 (48%), Gaps = 10/126 (7%)

Query: 423 SGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGD 482
           SGGG     S GGG  G  SGG   G  SGGG  G  GGG GG    G GG   G  GG 
Sbjct: 513 SGGG-----SRGGGGGGYGSGGSSYG--SGGGSYGSGGGGGGGRGSYGSGGSSYGSGGGS 565

Query: 483 RGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSGYG 542
            G  GG  G G  G     GG RGG GG  GG  G RG  GG  S GG  G RG  SG G
Sbjct: 566 YGSGGGGGGHGSYGSGSSSGGYRGGSGGGGGGSSGGRGSGGG--SSGGSIGGRGSSSG-G 622

Query: 543 GDRSGG 548
              SGG
Sbjct: 623 VKSSGG 628



 Score = 72.0 bits (175), Expect = 1e-12
 Identities = 60/170 (35%), Positives = 64/170 (37%), Gaps = 47/170 (27%)

Query: 313 IKVSFATRRPEFMRGGGSGGGRRGRGGYRGRGGFQGRGGDPKSGDWVCPNPSCGNMNFAR 372
           + VS +T       GG  GG   G GGY   G   G GG                     
Sbjct: 501 VSVSVSTSHTTISGGGSRGG---GGGGYGSGGSSYGSGG--------------------- 536

Query: 373 RNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGRGGR--GGDRGGYGGDRSGGGYG-- 428
                         S  SGG     G GG RG  G GG   G   G YG    GGG+G  
Sbjct: 537 -------------GSYGSGG-----GGGGGRGSYGSGGSSYGSGGGSYGSGGGGGGHGSY 578

Query: 429 GDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGG 478
           G  SS GGY G  SGGG GG   G G GG   GG  G RG   GG +  G
Sbjct: 579 GSGSSSGGYRGG-SGGGGGGSSGGRGSGGGSSGGSIGGRGSSSGGVKSSG 627



 Score = 63.5 bits (153), Expect = 5e-10
 Identities = 43/104 (41%), Positives = 44/104 (42%), Gaps = 26/104 (25%)

Query: 491 GGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSGYGGDRSGGYG 550
           GG  GG  GGYG     YG   G YG   GG GG   RG YG    GGS YG        
Sbjct: 515 GGSRGGGGGGYGSGGSSYGSGGGSYGSGGGGGGG---RGSYGS---GGSSYGS------- 561

Query: 551 GDRSGGGYGGDRGGG----------YGGDRGGYGGKMGGRNDYR 584
               GG YG   GGG           GG RGG GG  GG +  R
Sbjct: 562 ---GGGSYGSGGGGGGHGSYGSGSSSGGYRGGSGGGGGGSSGGR 602



 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 49/135 (36%), Positives = 53/135 (39%), Gaps = 26/135 (19%)

Query: 326 RGGGSGGGRRGRGGYRGRGGFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPE 385
           R  G GGGR    G  G GG  G GG                  F  R+  N        
Sbjct: 37  RRSGGGGGRFSSCG--GGGGSFGAGG-----------------GFGSRSLVNLGGSKSIS 77

Query: 386 DSRPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRSGGG------YGGDRSSGGGYSG 439
            S   GG  RG G+GG  G  G GG G   GG+GG   GGG       GG    GGG+ G
Sbjct: 78  ISVARGGG-RGSGFGGGYGGGGFGGGGFGGGGFGGGGIGGGGFGGFGSGGGGFGGGGFGG 136

Query: 440 DRSGGGYGGDRSGGG 454
              GGGYG     GG
Sbjct: 137 GGYGGGYGPVCPPGG 151



 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 42/116 (36%), Positives = 48/116 (41%), Gaps = 23/116 (19%)

Query: 327 GGGS----GGGRRGRGGYRGRGGFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEP 382
           GGGS    GGG  GRG Y   G   G GG    G +       G+ ++   +S       
Sbjct: 535 GGGSYGSGGGGGGGRGSYGSGGSSYGSGG----GSYGSGGGGGGHGSYGSGSS------- 583

Query: 383 RPEDSRPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYS 438
                  SGG   G G GG     GRG  GG  GG  G R G   GG +SSGG  S
Sbjct: 584 -------SGGYRGGSGGGGGGSSGGRGSGGGSSGGSIGGR-GSSSGGVKSSGGSSS 631



 Score = 46.2 bits (108), Expect = 8e-05
 Identities = 32/78 (41%), Positives = 34/78 (43%), Gaps = 6/78 (7%)

Query: 516 GGDRGGYGGDRSRGGYG-GDRGGGSGYGGDRSGGYGGDRSGGGYGGDRGGGYGGDRGGYG 574
           GG RGG GG     GYG G    GSG G   SGG GG   G    G    G GG   G G
Sbjct: 515 GGSRGGGGG-----GYGSGGSSYGSGGGSYGSGGGGGGGRGSYGSGGSSYGSGGGSYGSG 569

Query: 575 GKMGGRNDYRNDQRNRPY 592
           G  GG   Y +   +  Y
Sbjct: 570 GGGGGHGSYGSGSSSGGY 587



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 35/124 (28%), Positives = 42/124 (33%), Gaps = 8/124 (6%)

Query: 92  MESSGSQGGRAPSYDQPDYGQQDSYDQQSG-YDQHQGSYDEQSNYDQQHDSYSQNQQSYH 150
           +   GS+GG    Y         SY    G Y    G    + +Y     SY     SY 
Sbjct: 512 ISGGGSRGGGGGGYGSGG----SSYGSGGGSYGSGGGGGGGRGSYGSGGSSYGSGGGSYG 567

Query: 151 SQRENYSHHTQDDRRDVSRYGEDNRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFK 210
           S      H +         Y   + G GG   GGRG GG      G   G  G   GG K
Sbjct: 568 SGGGGGGHGSYGSGSSSGGYRGGSGGGGGGSSGGRGSGG---GSSGGSIGGRGSSSGGVK 624

Query: 211 NFGG 214
           + GG
Sbjct: 625 SSGG 628



 Score = 39.3 bits (90), Expect = 0.010
 Identities = 28/69 (40%), Positives = 30/69 (43%), Gaps = 2/69 (2%)

Query: 2   SDSGSYGQSGGEQQSYSTYGNPGSQGYGQASQSY-SGYGQTTDSSYGQNYSGYSSYGQSQ 60
           S  GSYG  GG      +YG+ GS  YG    SY SG G     SYG   S     G S 
Sbjct: 534 SGGGSYGSGGGGGGGRGSYGSGGS-SYGSGGGSYGSGGGGGGHGSYGSGSSSGGYRGGSG 592

Query: 61  SGYSQSYGG 69
            G   S GG
Sbjct: 593 GGGGGSSGG 601



 Score = 36.2 bits (82), Expect = 0.087
 Identities = 29/77 (37%), Positives = 32/77 (41%), Gaps = 8/77 (10%)

Query: 2   SDSGSYGQSGGEQQSYSTYGNPGSQGYGQASQSY-SGYGQTTDSSYGQNYSGYSSYGQSQ 60
           S  GSYG  GG        G  GS G G +S  Y  G G     S G   SG  S G S 
Sbjct: 561 SGGGSYGSGGGG-------GGHGSYGSGSSSGGYRGGSGGGGGGSSGGRGSGGGSSGGSI 613

Query: 61  SGYSQSYGGYENQKQSS 77
            G   S GG ++   SS
Sbjct: 614 GGRGSSSGGVKSSGGSS 630



 Score = 35.0 bits (79), Expect = 0.19
 Identities = 35/102 (34%), Positives = 38/102 (37%), Gaps = 12/102 (11%)

Query: 1   MSDSGSYGQSGGEQQSYSTYGNPGSQ-GYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQS 59
           +S  GS G  GG       YG+ GS  G G  S    G G     SYG   SG SSYG  
Sbjct: 512 ISGGGSRGGGGG------GYGSGGSSYGSGGGSYGSGGGGGGGRGSYG---SGGSSYGSG 562

Query: 60  QSGYSQSYGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGR 101
              Y    GG  +    S S       G        GS GGR
Sbjct: 563 GGSYGSGGGGGGHGSYGSGSSSGGYRGGSGGG--GGGSSGGR 602



 Score = 34.7 bits (78), Expect = 0.25
 Identities = 22/49 (44%), Positives = 26/49 (53%), Gaps = 2/49 (4%)

Query: 167 VSRYGEDNRGYGGSQGGGR-GRGGYDKDGRGPMTGSSGGDRGGFKNFGG 214
           V+R G    G+GG  GGG  G GG+   G G   G  GG  GGF + GG
Sbjct: 80  VARGGGRGSGFGGGYGGGGFGGGGFGGGGFGG-GGIGGGGFGGFGSGGG 127



 Score = 34.7 bits (78), Expect = 0.25
 Identities = 22/52 (42%), Positives = 23/52 (44%), Gaps = 1/52 (1%)

Query: 170 YGEDNRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGH-RDYGP 220
           YG    G GG  GGG G GG    G G      GG  GG    GG+   YGP
Sbjct: 94  YGGGGFGGGGFGGGGFGGGGIGGGGFGGFGSGGGGFGGGGFGGGGYGGGYGP 145



 Score = 34.3 bits (77), Expect = 0.33
 Identities = 34/104 (32%), Positives = 42/104 (40%), Gaps = 12/104 (11%)

Query: 2   SDSGSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQSQS 61
           S   SYG  GG      +YG+ G  G G+ S  Y   G +  S  G   SG    G    
Sbjct: 527 SGGSSYGSGGG------SYGSGGGGGGGRGS--YGSGGSSYGSGGGSYGSGGGGGGHGSY 578

Query: 62  GYSQSYGGYENQKQSSYSQQPYNNQGQQQNMESS-GSQGGRAPS 104
           G   S GGY   +  S      ++ G+     SS GS GGR  S
Sbjct: 579 GSGSSSGGY---RGGSGGGGGGSSGGRGSGGGSSGGSIGGRGSS 619



 Score = 31.2 bits (69), Expect = 2.8
 Identities = 18/39 (46%), Positives = 18/39 (46%)

Query: 176 GYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGG 214
           GYGG   GG G GG    G G   G  GG   G   FGG
Sbjct: 93  GYGGGGFGGGGFGGGGFGGGGIGGGGFGGFGSGGGGFGG 131


>gi|25777671 protein phosphatase 1, regulatory subunit 10 [Homo
           sapiens]
          Length = 940

 Score = 96.3 bits (238), Expect = 7e-20
 Identities = 98/265 (36%), Positives = 108/265 (40%), Gaps = 37/265 (13%)

Query: 327 GGGSGGGRRGRGGYRG----------RGG--FQGRGGDPKSGDWVCPNPSCGNMNFARRN 374
           GG   G   G GG  G          RGG  F    GDP  G  +   P  G   + R  
Sbjct: 648 GGPMPGPHGGPGGPVGPRLLGPPPPPRGGDPFWDGPGDPMRGGPMRGGPGPGPGPYHRGR 707

Query: 375 SCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSG 434
                NEP P    P  G   GR  GG     GRGG GG   G GG R   G GG   + 
Sbjct: 708 GGRGGNEPPPPPP-PFRGARGGRSGGGPPN--GRGGPGGGMVGGGGHRPHEGPGGGMGNS 764

Query: 435 GGYSGDRS-GGGYG-GDRSGGGYGGDRGGGYGGDR-----GGGYGGDRGG----GYGGDR 483
            G+      GGG G G R   G GG  GGG GG R     GGG  G  G     G GG  
Sbjct: 765 SGHRPHEGPGGGMGSGHRPHEGPGGSMGGG-GGHRPHEGPGGGISGGSGHRPHEGPGGGM 823

Query: 484 GGYGGDRGG-GYGGDRGGYGGDR----GGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGG- 537
           G  GG R   G GG  GG GG R     G+GG  G    D  G+ G   RG    +  G 
Sbjct: 824 GAGGGHRPHEGPGGSMGGSGGHRPHEGPGHGGPHGHRPHDVPGHRGHDHRGPPPHEHRGH 883

Query: 538 -GSGYGGDRSGGYGGDRSGGGYGGD 561
            G G+GG   GG+ G   G  +GGD
Sbjct: 884 DGPGHGG---GGHRGHDGGHSHGGD 905



 Score = 82.0 bits (201), Expect = 1e-15
 Identities = 88/255 (34%), Positives = 93/255 (36%), Gaps = 33/255 (12%)

Query: 336 GRGGYRGRGGFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFR 395
           G GG +G   F    G P  G    P    G               P P    P GGD  
Sbjct: 633 GPGGPKGMQHFPPGPGGPMPGPHGGPGGPVGP---------RLLGPPPP----PRGGDPF 679

Query: 396 GRGYGGE-RGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGG 454
             G G   RG   RGG G   G Y   R G G          + G R G      RSGGG
Sbjct: 680 WDGPGDPMRGGPMRGGPGPGPGPYHRGRGGRGGNEPPPPPPPFRGARGG------RSGGG 733

Query: 455 YGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGG 514
               RGG  GG  GGG G     G GG  G   G R         G GG  G       G
Sbjct: 734 PPNGRGGPGGGMVGGG-GHRPHEGPGGGMGNSSGHR------PHEGPGGGMGSGHRPHEG 786

Query: 515 YGGDRGGYGGDRSRGGYGGDRGGGSGY-----GGDRSGGYGGDRSGGGYGGDRGGGYGGD 569
            GG  GG GG R   G GG   GGSG+      G   G  GG R   G GG  GG  GG 
Sbjct: 787 PGGSMGGGGGHRPHEGPGGGISGGSGHRPHEGPGGGMGAGGGHRPHEGPGGSMGGS-GGH 845

Query: 570 RGGYGGKMGGRNDYR 584
           R   G   GG + +R
Sbjct: 846 RPHEGPGHGGPHGHR 860



 Score = 68.2 bits (165), Expect = 2e-11
 Identities = 95/295 (32%), Positives = 110/295 (37%), Gaps = 48/295 (16%)

Query: 323 EFMRGGGSGGGRRGRGGYR------GRGGFQGRGGDPKSGDWVCPNPSCGNMNFARRNSC 376
           E +  GGSGG   G GG +         G  G G  P+        P  G +N  +    
Sbjct: 535 ETLEPGGSGGSPDGAGGSKLPPVLANLMGSMGAGKGPQG-------PGGGGIN-VQEILT 586

Query: 377 NQCNEPRPEDSRPSGGDFRGRGYGGE-------RGYRGRG--GRGGDRGGYGGDRSGGGY 427
           +    P   +S PS    +   Y  +        G  G G    G   GG GG +  G  
Sbjct: 587 SIMGSP---NSHPSEELLKQPDYSDKIKQMLVPHGLLGPGPIANGFPPGGPGGPK--GMQ 641

Query: 428 GGDRSSGGGYSGDRSG-GGYGGDRSGGGYGGDRGGGYGGDRGGG--YGGDRGGGYGGDRG 484
                 GG   G   G GG  G R  G     RGG    D  G    GG   GG G   G
Sbjct: 642 HFPPGPGGPMPGPHGGPGGPVGPRLLGPPPPPRGGDPFWDGPGDPMRGGPMRGGPGPGPG 701

Query: 485 GYGGDRGGGYGGD--------RGGYGGDRGGYG--GDRGGYGGDRGGYGGDRSRGGYGGD 534
            Y   RGG  G +        RG  GG  GG G    RGG GG   G GG R   G GG 
Sbjct: 702 PYHRGRGGRGGNEPPPPPPPFRGARGGRSGG-GPPNGRGGPGGGMVGGGGHRPHEGPGGG 760

Query: 535 RGGGSGYGGDRSGGYG---GDRSGGGYGGDRGGGYGGDR--GGYGGKMGGRNDYR 584
            G  SG+      G G   G R   G GG  GGG GG R   G GG + G + +R
Sbjct: 761 MGNSSGHRPHEGPGGGMGSGHRPHEGPGGSMGGG-GGHRPHEGPGGGISGGSGHR 814



 Score = 56.6 bits (135), Expect = 6e-08
 Identities = 55/180 (30%), Positives = 65/180 (36%), Gaps = 45/180 (25%)

Query: 321 RPEFMRGGGSGGGRRGRGGYRGRGGFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCN 380
           RP    GGG G G R    + G GG  G GG                             
Sbjct: 768 RPHEGPGGGMGSGHR---PHEGPGGSMGGGG----------------------------- 795

Query: 381 EPRPEDSRPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGD 440
                  RP  G   G G  G  G+R   G GG  G  GG R   G GG     GG+   
Sbjct: 796 -----GHRPHEGP--GGGISGGSGHRPHEGPGGGMGAGGGHRPHEGPGGSMGGSGGHR-P 847

Query: 441 RSGGGYGGDRSGGGYG--GDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGG-GYGGD 497
             G G+GG      +   G RG  + G     + G  G G+GG  GG+ G  GG  +GGD
Sbjct: 848 HEGPGHGGPHGHRPHDVPGHRGHDHRGPPPHEHRGHDGPGHGG--GGHRGHDGGHSHGGD 905



 Score = 33.1 bits (74), Expect = 0.74
 Identities = 22/53 (41%), Positives = 28/53 (52%), Gaps = 7/53 (13%)

Query: 174 NRGYGGSQGGGRGRGGYDKDGRGPMTGSSG-----GDRGGFKNFGGHRDY-GP 220
           + G GGS GGG G   ++  G G ++G SG     G  GG    GGHR + GP
Sbjct: 784 HEGPGGSMGGGGGHRPHEGPG-GGISGGSGHRPHEGPGGGMGAGGGHRPHEGP 835



 Score = 29.6 bits (65), Expect = 8.2
 Identities = 18/46 (39%), Positives = 20/46 (43%), Gaps = 7/46 (15%)

Query: 182 GGGRGRGGYDKDGRGPMTGSSGGDR------GGFKNFGGHRDY-GP 220
           GGG G G    +G G   G  GG R      GG     GHR + GP
Sbjct: 774 GGGMGSGHRPHEGPGGSMGGGGGHRPHEGPGGGISGGSGHRPHEGP 819


>gi|47132620 keratin 2 [Homo sapiens]
          Length = 639

 Score = 95.9 bits (237), Expect = 9e-20
 Identities = 64/141 (45%), Positives = 73/141 (51%), Gaps = 10/141 (7%)

Query: 410 GRGGDRGGYGGDRSGGGY--GGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDR 467
           GRGG  GG+ G  SG     GG R S   +S     GG GG   GGG+G     G GG +
Sbjct: 11  GRGGGGGGFRGFSSGSAVVSGGSRRSTSSFSCLSRHGGGGGGFGGGGFGSRSLVGLGGTK 70

Query: 468 GGGYGGDRGGGYGGDRGGYGGDRGGGYGGDR---GGYGGDRGGYGGDRGGYGGDR-GGYG 523
                   GGG  G  GG+GG RGGG+GG     GG G   GG+GG  GG+GG R GG+G
Sbjct: 71  SISISVAGGGGGFGAAGGFGG-RGGGFGGGSSFGGGSGFSGGGFGG--GGFGGGRFGGFG 127

Query: 524 GDRSRGGYGGDRG-GGSGYGG 543
           G    GG GG  G G  GY G
Sbjct: 128 GPGGVGGLGGPGGFGPGGYPG 148



 Score = 87.8 bits (216), Expect = 3e-17
 Identities = 55/127 (43%), Positives = 58/127 (45%), Gaps = 14/127 (11%)

Query: 424 GGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDR 483
           GG  G   SSGGGYS   S  G GG R  G  GG  GGG     GGGYG   GGG GG  
Sbjct: 519 GGSGGRGSSSGGGYSSGSSSYGSGG-RQSGSRGGSGGGG--SISGGGYGS--GGGSGGRY 573

Query: 484 GGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSGYGG 543
           G  GG +GG   G         GGYG   G +    G  GG  S GGYG   GG S   G
Sbjct: 574 GSGGGSKGGSISG---------GGYGSGGGKHSSGGGSRGGSSSGGGYGSGGGGSSSVKG 624

Query: 544 DRSGGYG 550
                +G
Sbjct: 625 SSGEAFG 631



 Score = 86.7 bits (213), Expect = 6e-17
 Identities = 54/119 (45%), Positives = 58/119 (48%), Gaps = 9/119 (7%)

Query: 405 YRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYG 464
           + G GGRG   GG G       YG    SGG  SG R G G GG  SGGGYG   GGG G
Sbjct: 518 FGGSGGRGSSSGG-GYSSGSSSYG----SGGRQSGSRGGSGGGGSISGGGYGS--GGGSG 570

Query: 465 GDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYG 523
           G  G G GG +GG   G   G GG +    GG RGG     GGYG   GG    +G  G
Sbjct: 571 GRYGSG-GGSKGGSISGGGYGSGGGKHSSGGGSRGG-SSSGGGYGSGGGGSSSVKGSSG 627



 Score = 83.6 bits (205), Expect = 5e-16
 Identities = 59/129 (45%), Positives = 69/129 (53%), Gaps = 11/129 (8%)

Query: 390 SGGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGD 449
           SGG  R           G GG G   GG+ G RS  G GG +S     +G   GGG+G  
Sbjct: 30  SGGSRRSTSSFSCLSRHGGGGGGFGGGGF-GSRSLVGLGGTKSISISVAG--GGGGFG-- 84

Query: 450 RSGGGYGGDRGGGYGGDRG-GGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGY 508
            + GG+GG RGGG+GG    GG  G  GGG+GG  GG+GG R GG+GG  GG GG  G  
Sbjct: 85  -AAGGFGG-RGGGFGGGSSFGGGSGFSGGGFGG--GGFGGGRFGGFGGP-GGVGGLGGPG 139

Query: 509 GGDRGGYGG 517
           G   GGY G
Sbjct: 140 GFGPGGYPG 148



 Score = 81.6 bits (200), Expect = 2e-15
 Identities = 55/129 (42%), Positives = 58/129 (44%), Gaps = 12/129 (9%)

Query: 451 SGGGYGGDRGGGYGGDRGGGYG-GDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYG 509
           S   +GG   GG G   GGGY  G    G GG + G  G  GGG     GGYG      G
Sbjct: 514 SKAAFGGS--GGRGSSSGGGYSSGSSSYGSGGRQSGSRGGSGGGGSISGGGYGSG----G 567

Query: 510 GDRGGYGGDRGGYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDRGGGYGGD 569
           G  G YG   G  GG  S GGYG   G  S  GG R    GG  SGGGYG   GGG    
Sbjct: 568 GSGGRYGSGGGSKGGSISGGGYGSGGGKHSSGGGSR----GGSSSGGGYGSG-GGGSSSV 622

Query: 570 RGGYGGKMG 578
           +G  G   G
Sbjct: 623 KGSSGEAFG 631



 Score = 79.0 bits (193), Expect = 1e-14
 Identities = 68/168 (40%), Positives = 76/168 (45%), Gaps = 30/168 (17%)

Query: 335 RGRGGYRGRGGFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDF 394
           RGRGG  G GGF+G      SG  V    S       R  S   C           GG F
Sbjct: 10  RGRGG--GGGGFRGFS----SGSAVVSGGS------RRSTSSFSCLSRHGG----GGGGF 53

Query: 395 RGRGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGG 454
            G G+G  R   G GG         G   GGG+G      GG+ G   GGG+GG  S GG
Sbjct: 54  GGGGFGS-RSLVGLGGTKSISISVAG--GGGGFGA----AGGFGG--RGGGFGGGSSFGG 104

Query: 455 YGGDRGGGYGGDRGGGYGGDRGGGYGGDR--GGYGGDRGGGYGGDRGG 500
             G  GGG+G   GGG+GG R GG+GG    GG GG  G G GG  GG
Sbjct: 105 GSGFSGGGFG---GGGFGGGRFGGFGGPGGVGGLGGPGGFGPGGYPGG 149



 Score = 78.6 bits (192), Expect = 2e-14
 Identities = 59/143 (41%), Positives = 68/143 (47%), Gaps = 33/143 (23%)

Query: 395 RGRGYGGERGY----------------------RGRGGRGGDRGGYGGDRSGGGYGGDRS 432
           RG G GG RG+                      R  GG GG  GG  G RS  G GG +S
Sbjct: 12  RGGGGGGFRGFSSGSAVVSGGSRRSTSSFSCLSRHGGGGGGFGGGGFGSRSLVGLGGTKS 71

Query: 433 SG----GGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDR-GGYG 487
                 GG  G  + GG+GG   GGG+GG  G  +GG  G   GG  GGG+GG R GG+G
Sbjct: 72  ISISVAGGGGGFGAAGGFGG--RGGGFGG--GSSFGGGSGFSGGGFGGGGFGGGRFGGFG 127

Query: 488 GDRGGGYGGDRGGYGGDRGGYGG 510
           G  G G  G  GG+G   GGY G
Sbjct: 128 GPGGVGGLGGPGGFG--PGGYPG 148



 Score = 75.9 bits (185), Expect = 1e-13
 Identities = 49/104 (47%), Positives = 50/104 (48%), Gaps = 8/104 (7%)

Query: 392 GDFRGRGYGGERGYRGRGGR-GGDRGGYGGDRS--GGGYGGDRSSGGGYSGDRSGGGYGG 448
           G   G GY       G GGR  G RGG GG  S  GGGYG    SGG Y     GG  GG
Sbjct: 525 GSSSGGGYSSGSSSYGSGGRQSGSRGGSGGGGSISGGGYGSGGGSGGRYGS--GGGSKGG 582

Query: 449 DRSGGGYGGDRGGGYGGDRGGGYGG-DRGGGYGGDRGGYGGDRG 491
             SGGGYG   GGG     GG  GG   GGGYG   GG    +G
Sbjct: 583 SISGGGYGS--GGGKHSSGGGSRGGSSSGGGYGSGGGGSSSVKG 624



 Score = 73.9 bits (180), Expect = 4e-13
 Identities = 52/123 (42%), Positives = 57/123 (46%), Gaps = 9/123 (7%)

Query: 387 SRPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGY 446
           S+ + G   GRG     GY       G  G   G R G G GG   SGGGY    SGGG 
Sbjct: 514 SKAAFGGSGGRGSSSGGGYSSGSSSYGSGGRQSGSRGGSG-GGGSISGGGYG---SGGGS 569

Query: 447 GGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRG 506
           GG R G G GG +GG   G  G G GG +    GG RG  G   GGGYG   GG    +G
Sbjct: 570 GG-RYGSG-GGSKGGSISGG-GYGSGGGKHSSGGGSRG--GSSSGGGYGSGGGGSSSVKG 624

Query: 507 GYG 509
             G
Sbjct: 625 SSG 627



 Score = 73.6 bits (179), Expect = 5e-13
 Identities = 48/114 (42%), Positives = 50/114 (43%), Gaps = 19/114 (16%)

Query: 481 GDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSG 540
           G  GG G   GGGY      YG   G   G RGG GG     GG  S GGYG   G G  
Sbjct: 519 GGSGGRGSSSGGGYSSGSSSYGSG-GRQSGSRGGSGG-----GGSISGGGYGSGGGSGGR 572

Query: 541 YGGDRSGGYGGDRSGGGY----------GGDRGGGYGGDRGGYGGKMGGRNDYR 584
           YG    G  GG  SGGGY          GG RGG   G  GGYG   GG +  +
Sbjct: 573 YGSG-GGSKGGSISGGGYGSGGGKHSSGGGSRGGSSSG--GGYGSGGGGSSSVK 623



 Score = 64.7 bits (156), Expect = 2e-10
 Identities = 52/137 (37%), Positives = 57/137 (41%), Gaps = 26/137 (18%)

Query: 338 GGYRGRGGFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGR 397
           GG  GRG   G G    S  +     S G  + +R  S               GG   G 
Sbjct: 519 GGSGGRGSSSGGGYSSGSSSY----GSGGRQSGSRGGS-------------GGGGSISGG 561

Query: 398 GYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGG 457
           GYG   G  GR G GG  G  GG  SGGGYG   S GG +S    GG  GG  SGGGYG 
Sbjct: 562 GYGSGGGSGGRYGSGG--GSKGGSISGGGYG---SGGGKHSS--GGGSRGGSSSGGGYGS 614

Query: 458 DRGGGYG--GDRGGGYG 472
             GG     G  G  +G
Sbjct: 615 GGGGSSSVKGSSGEAFG 631



 Score = 52.8 bits (125), Expect = 9e-07
 Identities = 31/75 (41%), Positives = 34/75 (45%), Gaps = 7/75 (9%)

Query: 505 RGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDRGG 564
           +  +GG  G      GGY    S  G GG + G  G       G GG  SGGGYG   GG
Sbjct: 515 KAAFGGSGGRGSSSGGGYSSGSSSYGSGGRQSGSRG-----GSGGGGSISGGGYGS--GG 567

Query: 565 GYGGDRGGYGGKMGG 579
           G GG  G  GG  GG
Sbjct: 568 GSGGRYGSGGGSKGG 582



 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 38/120 (31%), Positives = 39/120 (32%), Gaps = 41/120 (34%)

Query: 326 RGGGSGGGRRGRGGYRGRGGFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPE 385
           RGG  GGG    GGY   GG  GR G                                  
Sbjct: 549 RGGSGGGGSISGGGYGSGGGSGGRYG---------------------------------S 575

Query: 386 DSRPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGG 445
                GG   G GYG   G    GG     G  GG  SGGGYG   S GGG S  +   G
Sbjct: 576 GGGSKGGSISGGGYGSGGGKHSSGG-----GSRGGSSSGGGYG---SGGGGSSSVKGSSG 627



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 39/103 (37%), Positives = 42/103 (40%), Gaps = 33/103 (32%)

Query: 329 GSGGGRRGRGGYRGRGGFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSR 388
           G GGG    GG+ GRGG  G GG    G         G   F                  
Sbjct: 78  GGGGGFGAAGGFGGRGG--GFGGGSSFG---------GGSGF------------------ 108

Query: 389 PSGGDFRGRGYGGER--GYRGRGGRGGDRGGYGGDRSGGGYGG 429
            SGG F G G+GG R  G+ G GG GG  GG GG   GG  GG
Sbjct: 109 -SGGGFGGGGFGGGRFGGFGGPGGVGG-LGGPGGFGPGGYPGG 149



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 27/59 (45%), Positives = 29/59 (49%), Gaps = 5/59 (8%)

Query: 527 SRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDRGGGYGG---DRGGY--GGKMGGR 580
           S+  +GG  G GS  GG  S G     SGG   G RGG  GG     GGY  GG  GGR
Sbjct: 514 SKAAFGGSGGRGSSSGGGYSSGSSSYGSGGRQSGSRGGSGGGGSISGGGYGSGGGSGGR 572



 Score = 34.7 bits (78), Expect = 0.25
 Identities = 29/102 (28%), Positives = 40/102 (39%), Gaps = 10/102 (9%)

Query: 1   MSDSGSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYG--Q 58
           ++   ++G SGG        G+    GY   S SY   G+ + S  G    G  S G   
Sbjct: 512 VASKAAFGGSGGR-------GSSSGGGYSSGSSSYGSGGRQSGSRGGSGGGGSISGGGYG 564

Query: 59  SQSGYSQSYGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGG 100
           S  G    YG     K  S S   Y + G + +    GS+GG
Sbjct: 565 SGGGSGGRYGSGGGSKGGSISGGGYGSGGGKHS-SGGGSRGG 605



 Score = 34.7 bits (78), Expect = 0.25
 Identities = 27/68 (39%), Positives = 31/68 (45%), Gaps = 2/68 (2%)

Query: 4   SGSYGQSGGEQQ-SYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQSQSG 62
           SGS G SGG    S   YG+ G  G    S   S  G  +   YG     +SS G S+ G
Sbjct: 546 SGSRGGSGGGGSISGGGYGSGGGSGGRYGSGGGSKGGSISGGGYGSGGGKHSSGGGSRGG 605

Query: 63  YSQSYGGY 70
            S S GGY
Sbjct: 606 -SSSGGGY 612



 Score = 34.3 bits (77), Expect = 0.33
 Identities = 28/84 (33%), Positives = 32/84 (38%), Gaps = 13/84 (15%)

Query: 171 GEDNRGYGGSQGGGRG---------RGGYDK-DGRGPMTGSSGGDRGGFKNFGGHRDYGP 220
           G  + G GG Q G RG          GGY    G G   GS GG +GG  + GG   YG 
Sbjct: 535 GSSSYGSGGRQSGSRGGSGGGGSISGGGYGSGGGSGGRYGSGGGSKGGSISGGG---YGS 591

Query: 221 RTDADSESDNSDNNTIFVQGLGEG 244
                S    S   +    G G G
Sbjct: 592 GGGKHSSGGGSRGGSSSGGGYGSG 615



 Score = 33.9 bits (76), Expect = 0.43
 Identities = 21/51 (41%), Positives = 25/51 (49%), Gaps = 6/51 (11%)

Query: 169 RYGEDNRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYG 219
           RYG      GGS+GG    GGY   G    +G  GG RGG  + GG+   G
Sbjct: 572 RYGSG----GGSKGGSISGGGYGSGGGKHSSG--GGSRGGSSSGGGYGSGG 616



 Score = 31.6 bits (70), Expect = 2.1
 Identities = 25/74 (33%), Positives = 30/74 (40%), Gaps = 4/74 (5%)

Query: 157 SHHTQDDRRDVSRYGEDNRGY--GGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGG 214
           S +    R+  SR G    G   GG  G G G GG    G G   GS  G  GG+ + GG
Sbjct: 537 SSYGSGGRQSGSRGGSGGGGSISGGGYGSGGGSGGRYGSGGGSKGGSISG--GGYGSGGG 594

Query: 215 HRDYGPRTDADSES 228
               G  +   S S
Sbjct: 595 KHSSGGGSRGGSSS 608



 Score = 31.2 bits (69), Expect = 2.8
 Identities = 22/70 (31%), Positives = 26/70 (37%), Gaps = 1/70 (1%)

Query: 176 GYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFK-NFGGHRDYGPRTDADSESDNSDNN 234
           G G S GGG   G       G  +GS GG  GG   + GG+   G           S   
Sbjct: 523 GRGSSSGGGYSSGSSSYGSGGRQSGSRGGSGGGGSISGGGYGSGGGSGGRYGSGGGSKGG 582

Query: 235 TIFVQGLGEG 244
           +I   G G G
Sbjct: 583 SISGGGYGSG 592



 Score = 29.6 bits (65), Expect = 8.2
 Identities = 15/25 (60%), Positives = 16/25 (64%), Gaps = 2/25 (8%)

Query: 327 GGGSGGGRRGRGGYRGRGGFQGRGG 351
           GGG GGGR G  G+ G GG  G GG
Sbjct: 115 GGGFGGGRFG--GFGGPGGVGGLGG 137



 Score = 29.6 bits (65), Expect = 8.2
 Identities = 20/63 (31%), Positives = 26/63 (41%), Gaps = 1/63 (1%)

Query: 5   GSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSY-GQSQSGY 63
           G YG  GG +    + G  GS G   +S   S  G ++   YG    G SS  G S   +
Sbjct: 571 GRYGSGGGSKGGSISGGGYGSGGGKHSSGGGSRGGSSSGGGYGSGGGGSSSVKGSSGEAF 630

Query: 64  SQS 66
             S
Sbjct: 631 GSS 633


>gi|58761498 heterogeneous nuclear ribonucleoprotein A1-like [Homo
           sapiens]
          Length = 320

 Score = 94.0 bits (232), Expect = 4e-19
 Identities = 86/286 (30%), Positives = 119/286 (41%), Gaps = 67/286 (23%)

Query: 221 RTDADSESDNSDNNTIFVQGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTG 280
           R D+     +     IFV G+ E      + ++F+Q G I+        +I + TD+ +G
Sbjct: 92  REDSQRPGAHLTVKKIFVGGIKEDTEEHHLRDYFEQYGKIE--------VIEIMTDRGSG 143

Query: 281 KPKGEATVSFDDPPSAKAAIDWFDGKEFH---GNIIKVSFATRRPEFMRGGGSGGGRRGR 337
           K +G A V+FDD  S    +D    +++H   G+  +V  A  + E      S  GRRG 
Sbjct: 144 KKRGFAFVTFDDHDS----VDKIVIQKYHTVKGHNCEVRKALPKQEMASASSSQRGRRGS 199

Query: 338 GGYRGRGGFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGR 397
           G +   GG +G G               GN NF R                  GG+F GR
Sbjct: 200 GNF---GGGRGDGFG-------------GNDNFGR------------------GGNFSGR 225

Query: 398 -GYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYG 456
            G+GG  G  G GG G    G+G D S  G GG  +  G Y+   S            +G
Sbjct: 226 GGFGGSCGGGGYGGSGDGYNGFGNDGSNFGGGGSYNDFGNYNNQSS-----------NFG 274

Query: 457 GDRGGGYGGDRGGGYGGDRGGGYGG---DRGGYG-GDRGGGYGGDR 498
             +GG +GG   G YGG  GG Y     ++GGYG       YG  R
Sbjct: 275 PMKGGNFGGRSSGPYGG--GGQYFAKPQNQGGYGVSSSSSSYGSGR 318



 Score = 86.3 bits (212), Expect = 7e-17
 Identities = 54/130 (41%), Positives = 67/130 (51%), Gaps = 21/130 (16%)

Query: 448 GDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGG 507
           G R  G +GG RG G+GG+   G    RGG + G RGG+GG  GGG      GYGG   G
Sbjct: 195 GRRGSGNFGGGRGDGFGGNDNFG----RGGNFSG-RGGFGGSCGGG------GYGGSGDG 243

Query: 508 YGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDRGGGYG 567
           Y G    +G D   +GG  S   +G      S +G  + G +GG RS G YGG  GG Y 
Sbjct: 244 YNG----FGNDGSNFGGGGSYNDFGNYNNQSSNFGPMKGGNFGG-RSSGPYGG--GGQYF 296

Query: 568 G---DRGGYG 574
               ++GGYG
Sbjct: 297 AKPQNQGGYG 306



 Score = 85.1 bits (209), Expect = 2e-16
 Identities = 56/137 (40%), Positives = 65/137 (47%), Gaps = 12/137 (8%)

Query: 432 SSGGGYSGDRSGGGYGGDRSGGGYGGD----RGGGYGGDRGGGYGGDRGGGYGGDRGGYG 487
           S+     G R  G +GG R G G+GG+    RGG + G RGG  G   GGGYGG   GY 
Sbjct: 188 SASSSQRGRRGSGNFGGGR-GDGFGGNDNFGRGGNFSG-RGGFGGSCGGGGYGGSGDGYN 245

Query: 488 --GDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSGYGGDR 545
             G+ G  +GG  GG   D G Y      +G  +GG  G RS G YGG  GG        
Sbjct: 246 GFGNDGSNFGG--GGSYNDFGNYNNQSSNFGPMKGGNFGGRSSGPYGG--GGQYFAKPQN 301

Query: 546 SGGYGGDRSGGGYGGDR 562
            GGYG   S   YG  R
Sbjct: 302 QGGYGVSSSSSSYGSGR 318



 Score = 85.1 bits (209), Expect = 2e-16
 Identities = 54/135 (40%), Positives = 64/135 (47%), Gaps = 10/135 (7%)

Query: 402 ERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGG 461
           +RG RG G  GG RG   G     G GG+ S  GG+ G   GGGYGG  SG GY G   G
Sbjct: 193 QRGRRGSGNFGGGRGDGFGGNDNFGRGGNFSGRGGFGGSCGGGGYGG--SGDGYNG--FG 248

Query: 462 GYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGG-DRGGYGGDRGGYGGDRGGYGGDRG 520
             G + GGG   +  G Y      +G  +GG +GG   G YGG     GG       ++G
Sbjct: 249 NDGSNFGGGGSYNDFGNYNNQSSNFGPMKGGNFGGRSSGPYGG-----GGQYFAKPQNQG 303

Query: 521 GYGGDRSRGGYGGDR 535
           GYG   S   YG  R
Sbjct: 304 GYGVSSSSSSYGSGR 318



 Score = 69.7 bits (169), Expect = 7e-12
 Identities = 49/113 (43%), Positives = 59/113 (52%), Gaps = 18/113 (15%)

Query: 465 GDRGGG-YGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYG 523
           G RG G +GG RG G+GG+   +G  RGG + G RGG+GG  GG     GGYGG   GY 
Sbjct: 195 GRRGSGNFGGGRGDGFGGN-DNFG--RGGNFSG-RGGFGGSCGG-----GGYGGSGDGYN 245

Query: 524 GDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDRGGGYGG-DRGGYGG 575
           G    G  G + GGG  Y     G Y    S   +G  +GG +GG   G YGG
Sbjct: 246 GF---GNDGSNFGGGGSYND--FGNYNNQSSN--FGPMKGGNFGGRSSGPYGG 291



 Score = 53.5 bits (127), Expect = 5e-07
 Identities = 31/67 (46%), Positives = 38/67 (56%), Gaps = 9/67 (13%)

Query: 524 GDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSG-GGYGGDRGGGYGGDRGGYGGKMGGRND 582
           G R  G +GG RG   G+GG+ + G GG+ SG GG+GG  GGG      GYGG   G N 
Sbjct: 195 GRRGSGNFGGGRG--DGFGGNDNFGRGGNFSGRGGFGGSCGGG------GYGGSGDGYNG 246

Query: 583 YRNDQRN 589
           + ND  N
Sbjct: 247 FGNDGSN 253



 Score = 52.8 bits (125), Expect = 9e-07
 Identities = 38/83 (45%), Positives = 45/83 (54%), Gaps = 20/83 (24%)

Query: 506 GGYGGDRG-GYGG-DRGGYGGDRS-RGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDR 562
           G +GG RG G+GG D  G GG+ S RGG+GG  GGG         GYGG  SG GY    
Sbjct: 200 GNFGGGRGDGFGGNDNFGRGGNFSGRGGFGGSCGGG---------GYGG--SGDGY---- 244

Query: 563 GGGYGGDRGGYGGKMGGRNDYRN 585
             G+G D   +GG  G  ND+ N
Sbjct: 245 -NGFGNDGSNFGGG-GSYNDFGN 265



 Score = 39.7 bits (91), Expect = 0.008
 Identities = 28/108 (25%), Positives = 42/108 (38%), Gaps = 9/108 (8%)

Query: 6   SYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQ--SQSGY 63
           ++G+ G         G+ G  GYG +   Y+G+G       G N+ G  SY    + +  
Sbjct: 215 NFGRGGNFSGRGGFGGSCGGGGYGGSGDGYNGFGND-----GSNFGGGGSYNDFGNYNNQ 269

Query: 64  SQSYGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYG 111
           S ++G  +       S  PY   GQ        +QGG   S     YG
Sbjct: 270 SSNFGPMKGGNFGGRSSGPYGGGGQY--FAKPQNQGGYGVSSSSSSYG 315



 Score = 36.6 bits (83), Expect = 0.067
 Identities = 18/45 (40%), Positives = 22/45 (48%), Gaps = 11/45 (24%)

Query: 546 SGGYGGDRSGGGYGGDRGGGYGGD-----------RGGYGGKMGG 579
           S    G R  G +GG RG G+GG+           RGG+GG  GG
Sbjct: 190 SSSQRGRRGSGNFGGGRGDGFGGNDNFGRGGNFSGRGGFGGSCGG 234



 Score = 35.8 bits (81), Expect = 0.11
 Identities = 33/126 (26%), Positives = 46/126 (36%), Gaps = 12/126 (9%)

Query: 16  SYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQS-----QSGYSQSYGGY 70
           S S  G  GS  +G       G+G   +   G N+SG   +G S       G    Y G+
Sbjct: 190 SSSQRGRRGSGNFGGGRGD--GFGGNDNFGRGGNFSGRGGFGGSCGGGGYGGSGDGYNGF 247

Query: 71  ENQKQSSYSQQPYNNQGQQQNMESS--GSQGGRAPSYDQPDYGQQDSYDQQSGYDQHQGS 128
            N   +      YN+ G   N  S+    +GG         YG    Y  +    Q+QG 
Sbjct: 248 GNDGSNFGGGGSYNDFGNYNNQSSNFGPMKGGNFGGRSSGPYGGGGQYFAK---PQNQGG 304

Query: 129 YDEQSN 134
           Y   S+
Sbjct: 305 YGVSSS 310



 Score = 34.7 bits (78), Expect = 0.25
 Identities = 39/124 (31%), Positives = 52/124 (41%), Gaps = 16/124 (12%)

Query: 139 HDSYSQNQ-QSYHSQR-ENYSHHTQDDRRDVSRYGEDNRGYGGSQ--GGGRGRG--GYDK 192
           HDS  +   Q YH+ +  N        +++++      RG  GS   GGGRG G  G D 
Sbjct: 156 HDSVDKIVIQKYHTVKGHNCEVRKALPKQEMASASSSQRGRRGSGNFGGGRGDGFGGNDN 215

Query: 193 DGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDADSESDNSDNNTIFVQGLGEGVSTDQVGE 252
            GRG   G+  G RGGF    G   YG   D  +   N  +N       G G S +  G 
Sbjct: 216 FGRG---GNFSG-RGGFGGSCGGGGYGGSGDGYNGFGNDGSN------FGGGGSYNDFGN 265

Query: 253 FFKQ 256
           +  Q
Sbjct: 266 YNNQ 269



 Score = 33.9 bits (76), Expect = 0.43
 Identities = 30/97 (30%), Positives = 39/97 (40%), Gaps = 13/97 (13%)

Query: 5   GSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQSQSGYS 64
           G YG SG     Y+ +GN GS   G  S +  G      S++G    G  ++G   SG  
Sbjct: 235 GGYGGSG---DGYNGFGNDGSNFGGGGSYNDFGNYNNQSSNFGPMKGG--NFGGRSSG-- 287

Query: 65  QSYGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGR 101
             YGG        Y  +P N  G   +  SS    GR
Sbjct: 288 -PYGG-----GGQYFAKPQNQGGYGVSSSSSSYGSGR 318



 Score = 33.1 bits (74), Expect = 0.74
 Identities = 23/64 (35%), Positives = 29/64 (45%), Gaps = 7/64 (10%)

Query: 171 GEDNRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGF----KNFGGHRDYGPRTDADS 226
           G DN G GG+     GRGG+     G   G SG    GF     NFGG   Y    + ++
Sbjct: 212 GNDNFGRGGNF---SGRGGFGGSCGGGGYGGSGDGYNGFGNDGSNFGGGGSYNDFGNYNN 268

Query: 227 ESDN 230
           +S N
Sbjct: 269 QSSN 272


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.309    0.140    0.437 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 31,336,228
Number of Sequences: 37866
Number of extensions: 2287892
Number of successful extensions: 68383
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 565
Number of HSP's successfully gapped in prelim test: 501
Number of HSP's that attempted gapping in prelim test: 14159
Number of HSP's gapped (non-prelim): 19912
length of query: 592
length of database: 18,247,518
effective HSP length: 108
effective length of query: 484
effective length of database: 14,157,990
effective search space: 6852467160
effective search space used: 6852467160
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.