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Search of human proteins with 21071067
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|21071067 TBP-associated factor 5 [Homo sapiens]
(800 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|21071067 TBP-associated factor 5 [Homo sapiens] 1619 0.0
gi|7657439 PCAF associated factor 65 beta isoform a [Homo sapiens] 372 e-103
gi|16554629 WD repeat domain 5 [Homo sapiens] 146 8e-35
gi|16554627 WD repeat domain 5 [Homo sapiens] 146 8e-35
gi|23199987 WD repeat domain 5B [Homo sapiens] 144 2e-34
gi|113865883 WD repeat domain 38 [Homo sapiens] 137 3e-32
gi|83779014 katanin p80 subunit B 1 [Homo sapiens] 137 4e-32
gi|26665869 WD repeat domain 51B [Homo sapiens] 136 7e-32
gi|32189425 WD repeat domain 69 [Homo sapiens] 135 1e-31
gi|239787764 WD repeat domain 51A isoform 3 [Homo sapiens] 126 7e-29
gi|239787760 WD repeat domain 51A isoform 2 [Homo sapiens] 126 7e-29
gi|239787754 WD repeat domain 51A isoform 1 [Homo sapiens] 126 7e-29
gi|19913371 transducin (beta)-like 1 X-linked receptor 1 [Homo s... 123 6e-28
gi|61743926 F-box and WD repeat domain containing 7 isoform 3 [H... 118 2e-26
gi|16117781 F-box and WD repeat domain containing 7 isoform 1 [H... 118 2e-26
gi|16117779 F-box and WD repeat domain containing 7 isoform 2 [H... 118 2e-26
gi|5729852 guanine nucleotide-binding protein, beta-5 subunit is... 117 4e-26
gi|20336270 guanine nucleotide-binding protein, beta-5 subunit i... 117 4e-26
gi|19913367 transducin beta-like 1Y [Homo sapiens] 116 7e-26
gi|19913365 transducin beta-like 1Y [Homo sapiens] 116 7e-26
gi|15150805 transducin beta-like 1Y [Homo sapiens] 116 7e-26
gi|70909324 sperm associated antigen 16 isoform 1 [Homo sapiens] 115 2e-25
gi|4557741 platelet-activating factor acetylhydrolase, isoform I... 114 4e-25
gi|11321585 guanine nucleotide-binding protein, beta-1 subunit [... 114 4e-25
gi|213021190 transducin beta-like 1X isoform b [Homo sapiens] 112 1e-24
gi|213021188 transducin beta-like 1X isoform b [Homo sapiens] 112 1e-24
gi|213021186 transducin beta-like 1X isoform a [Homo sapiens] 112 1e-24
gi|5032159 transducin beta-like 1X isoform a [Homo sapiens] 112 1e-24
gi|20357529 guanine nucleotide-binding protein, beta-2 subunit [... 112 1e-24
gi|24431950 PRP4 pre-mRNA processing factor 4 homolog [Homo sapi... 112 2e-24
>gi|21071067 TBP-associated factor 5 [Homo sapiens]
Length = 800
Score = 1619 bits (4192), Expect = 0.0
Identities = 800/800 (100%), Positives = 800/800 (100%)
Query: 1 MAALAEEQTEVAVKLEPEGPPTLLPPQAGDGAGEGSGGTTNNGPNGGGGNVAASSSTGGD 60
MAALAEEQTEVAVKLEPEGPPTLLPPQAGDGAGEGSGGTTNNGPNGGGGNVAASSSTGGD
Sbjct: 1 MAALAEEQTEVAVKLEPEGPPTLLPPQAGDGAGEGSGGTTNNGPNGGGGNVAASSSTGGD 60
Query: 61 GGTPKPTVAVSAAAPAGAAPVPAAAPDAGAPHDRQTLLAVLQFLRQSKLREAEEALRREA 120
GGTPKPTVAVSAAAPAGAAPVPAAAPDAGAPHDRQTLLAVLQFLRQSKLREAEEALRREA
Sbjct: 61 GGTPKPTVAVSAAAPAGAAPVPAAAPDAGAPHDRQTLLAVLQFLRQSKLREAEEALRREA 120
Query: 121 GLLEEAVAGSGAPGEVDSAGAEVTSALLSRVTASAPGPAAPDPPGTGASGATVVSGSASG 180
GLLEEAVAGSGAPGEVDSAGAEVTSALLSRVTASAPGPAAPDPPGTGASGATVVSGSASG
Sbjct: 121 GLLEEAVAGSGAPGEVDSAGAEVTSALLSRVTASAPGPAAPDPPGTGASGATVVSGSASG 180
Query: 181 PAAPGKVGSVAVEDQPDVSAVLSAYNQQGDPTMYEEYYSGLKHFIECSLDCHRAELSQLF 240
PAAPGKVGSVAVEDQPDVSAVLSAYNQQGDPTMYEEYYSGLKHFIECSLDCHRAELSQLF
Sbjct: 181 PAAPGKVGSVAVEDQPDVSAVLSAYNQQGDPTMYEEYYSGLKHFIECSLDCHRAELSQLF 240
Query: 241 YPLFVHMYLELVYNQHENEAKSFFEKFHGDQECYYQDDLRVLSSLTKKEHMKGNETMLDF 300
YPLFVHMYLELVYNQHENEAKSFFEKFHGDQECYYQDDLRVLSSLTKKEHMKGNETMLDF
Sbjct: 241 YPLFVHMYLELVYNQHENEAKSFFEKFHGDQECYYQDDLRVLSSLTKKEHMKGNETMLDF 300
Query: 301 RTSKFVLRISRDSYQLLKRHLQEKQNNQIWNIVQEHLYIDIFDGMPRSKQQIDAMVGSLA 360
RTSKFVLRISRDSYQLLKRHLQEKQNNQIWNIVQEHLYIDIFDGMPRSKQQIDAMVGSLA
Sbjct: 301 RTSKFVLRISRDSYQLLKRHLQEKQNNQIWNIVQEHLYIDIFDGMPRSKQQIDAMVGSLA 360
Query: 361 GEAKREANKSKVFFGLLKEPEIEVPLDDEDEEGENEEGKPKKKKPKKDSIGSKSKKQDPN 420
GEAKREANKSKVFFGLLKEPEIEVPLDDEDEEGENEEGKPKKKKPKKDSIGSKSKKQDPN
Sbjct: 361 GEAKREANKSKVFFGLLKEPEIEVPLDDEDEEGENEEGKPKKKKPKKDSIGSKSKKQDPN 420
Query: 421 APPQNRIPLPELKDSDKLDKIMNMKETTKRVRLGPDCLPSICFYTFLNAYQGLTAVDVTD 480
APPQNRIPLPELKDSDKLDKIMNMKETTKRVRLGPDCLPSICFYTFLNAYQGLTAVDVTD
Sbjct: 421 APPQNRIPLPELKDSDKLDKIMNMKETTKRVRLGPDCLPSICFYTFLNAYQGLTAVDVTD 480
Query: 481 DSSLIAGGFADSTVRVWSVTPKKLRSVKQASDLSLIDKESDDVLERIMDEKTASELKILY 540
DSSLIAGGFADSTVRVWSVTPKKLRSVKQASDLSLIDKESDDVLERIMDEKTASELKILY
Sbjct: 481 DSSLIAGGFADSTVRVWSVTPKKLRSVKQASDLSLIDKESDDVLERIMDEKTASELKILY 540
Query: 541 GHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPYGYYF 600
GHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPYGYYF
Sbjct: 541 GHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPYGYYF 600
Query: 601 VSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLNGN 660
VSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLNGN
Sbjct: 601 VSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLNGN 660
Query: 661 CVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFS 720
CVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFS
Sbjct: 661 CVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFS 720
Query: 721 RDGEILASGSMDNTVRLWDAIKAFEDLETDDFTTATGHINLPENSQELLLGTYMTKSTPV 780
RDGEILASGSMDNTVRLWDAIKAFEDLETDDFTTATGHINLPENSQELLLGTYMTKSTPV
Sbjct: 721 RDGEILASGSMDNTVRLWDAIKAFEDLETDDFTTATGHINLPENSQELLLGTYMTKSTPV 780
Query: 781 VHLHFTRRNLVLAAGAYSPQ 800
VHLHFTRRNLVLAAGAYSPQ
Sbjct: 781 VHLHFTRRNLVLAAGAYSPQ 800
>gi|7657439 PCAF associated factor 65 beta isoform a [Homo sapiens]
Length = 589
Score = 372 bits (956), Expect = e-103
Identities = 228/632 (36%), Positives = 330/632 (52%), Gaps = 80/632 (12%)
Query: 169 SGATVVSGSASGPAAPGKVGSVAVEDQPDVSAVLSAYNQQGDPTMYEEYYSGLKHFIECS 228
S + G A ++ V+ + + ++SA Q +P YE + L++F+ S
Sbjct: 25 SDGPLKQGLRLSQTAEEMAANLTVQSESGCANIVSAAPCQAEPQQYEVQFGRLRNFLTDS 84
Query: 229 LDCHRAELSQLFYPLFVHMYLELVYNQHENEAKSFFEKFHGDQECYYQDDLRVLSSLTKK 288
H E+ L YPLFV+++L LV N ++ +SF+ +FHG L + ++K
Sbjct: 85 DSQHSHEVMPLLYPLFVYLHLNLVQNSPKSTVESFYSRFHG----------MFLQNASQK 134
Query: 289 ---EHMKGNETMLDFRTSKFVLRISRDSYQLLKRHLQEKQNNQIWNIVQEHLYIDIFDGM 345
E ++ +T+ D S F LR D+ +++ LQE N + +Q
Sbjct: 135 DVIEQLQTTQTIQDI-LSNFKLRAFLDNKYVVR--LQEDSYNYLIRYLQSD--------- 182
Query: 346 PRSKQQIDAMVGSLAGEAKREANKSKVFFGLLKEPEIEVPLDDEDEEGENEEGKPKKKKP 405
N + L K + + LD + K+
Sbjct: 183 ----------------------NNT----ALCKVLTLHIHLDVQPA---------KRTDY 207
Query: 406 KKDSIGSKSKKQDPNAPPQNRIPLPELKDSDKLDKIMNMKETTKRVRLGPDCLPSICFYT 465
+ + GS S+ ++ P + +P P L++ L+ + +E+ KRV+ GP L +ICFY
Sbjct: 208 QLYASGSSSRSENNGLEPPD-MPSPILQNEAALEVL---QESIKRVKDGPPSLTTICFYA 263
Query: 466 FLNAYQGLTAVDVTDDSSLIAGGFADSTVRVWSVTPKKLRSVKQASDLSLIDKESDDVLE 525
F N Q L +++ DS L+A GF +S +++WS+ KKL+S D+S I D +LE
Sbjct: 264 FYNTEQLLNTAEISPDSKLLAAGFDNSCIKLWSLRSKKLKSEPHQVDVSRIHLACD-ILE 322
Query: 526 RIMDE--KTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKG 583
DE +E+KIL GH GPVY F D + LLS SED ++R W L +FT V Y+G
Sbjct: 323 EEDDEDDNAGTEMKILRGHCGPVYSTRFLADSSGLLSCSEDMSIRYWDLGSFTNTVLYQG 382
Query: 584 HNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVA 643
H YPVWD SPY YF SG HDR ARLW+ D PLRI+AGHLADV+C +FHPNSNY+A
Sbjct: 383 HAYPVWDLDISPYSLYFASGSHDRTARLWSFDRTYPLRIYAGHLADVDCVKFHPNSNYLA 442
Query: 644 TGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLM 703
TGS D+TVRLW GN VR+FTGH+GP+ SL FSPNG++LA+ D R+ LWD+ G +
Sbjct: 443 TGSTDKTVRLWSAQQGNSVRLFTGHRGPVLSLAFSPNGKYLASAGEDQRLKLWDLASGTL 502
Query: 704 VGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLWDAIKAFEDLETDDFTTATGHINLPE 763
EL+GHTD + SL FS D ++AS SMDN+VR+WD + D
Sbjct: 503 YKELRGHTDNITSLTFSPDSGLIASASMDNSVRVWDIRNTYCSAPAD------------- 549
Query: 764 NSQELLLGTYMTKSTPVVHLHFTRRNLVLAAG 795
S L+G Y + + V+ + F NL+L G
Sbjct: 550 GSSSELVGVYTGQMSNVLSVQFMACNLLLVTG 581
>gi|16554629 WD repeat domain 5 [Homo sapiens]
Length = 334
Score = 146 bits (368), Expect = 8e-35
Identities = 86/292 (29%), Positives = 147/292 (50%), Gaps = 17/292 (5%)
Query: 464 YTFLNAYQGLTAVDVTDDSSLIAGGFADSTVRVWSVTPKK-----------LRSVKQASD 512
+T + +++V + + +A AD +++W K + V +SD
Sbjct: 39 FTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSD 98
Query: 513 LSLIDKESDDVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSL 572
+L+ SDD +I D + LK L GHS V+ +F+P N ++S S D +VR+W +
Sbjct: 99 SNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDV 158
Query: 573 QTFTCLVGYKGHNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLR-IFAGHLADVN 631
+T CL H+ PV F+ G VS +D + R+W T Q L+ + V+
Sbjct: 159 KTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVS 218
Query: 632 CTRFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSL--TFS-PNGRFLATGA 688
+F PN Y+ + D T++LWD G C++ +TGHK + + FS G+++ +G+
Sbjct: 219 FVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGS 278
Query: 689 TDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDN--TVRLW 738
D V +W++ +V +L+GHTD V S I+AS +++N T++LW
Sbjct: 279 EDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLW 330
Score = 122 bits (305), Expect = 2e-27
Identities = 66/223 (29%), Positives = 106/223 (47%), Gaps = 7/223 (3%)
Query: 539 LYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPYGY 598
L GH+ V FSP+ +L SSS D +++W GH + D +S
Sbjct: 41 LAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSN 100
Query: 599 YFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLN 658
VS D+ ++W + L+ GH V C F+P SN + +GS D +VR+WDV
Sbjct: 101 LLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKT 160
Query: 659 GNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGEL-KGHTDTVCSL 717
G C++ H P+ ++ F+ +G + + + DG +WD G + L V +
Sbjct: 161 GKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFV 220
Query: 718 RFSRDGEILASGSMDNTVRLWDAIKAFEDLETDDFTTATGHIN 760
+FS +G+ + + ++DNT++LWD K T TGH N
Sbjct: 221 KFSPNGKYILAATLDNTLKLWDYSKG------KCLKTYTGHKN 257
Score = 115 bits (289), Expect = 1e-25
Identities = 68/242 (28%), Positives = 115/242 (47%), Gaps = 4/242 (1%)
Query: 502 KKLRSVKQASDLSLIDKESDDVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSS 561
K + SVK + + + S D L +I K + GH + ++S D N L+S+
Sbjct: 46 KAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSA 105
Query: 562 SEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLR 621
S+D T+++W + + CL KGH+ V+ F+P VSG D R+W + L+
Sbjct: 106 SDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLK 165
Query: 622 IFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLNGNCVR-IFTGHKGPIHSLTFSPN 680
H V+ F+ + + + + S D R+WD +G C++ + P+ + FSPN
Sbjct: 166 TLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPN 225
Query: 681 GRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSL--RFS-RDGEILASGSMDNTVRL 737
G+++ D + LWD G + GH + + FS G+ + SGS DN V +
Sbjct: 226 GKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYI 285
Query: 738 WD 739
W+
Sbjct: 286 WN 287
Score = 109 bits (272), Expect = 1e-23
Identities = 53/192 (27%), Positives = 95/192 (49%), Gaps = 3/192 (1%)
Query: 583 GHNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYV 642
GH V +FSP G + S D++ ++W + + +GH ++ + +SN +
Sbjct: 43 GHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLL 102
Query: 643 ATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGL 702
+ S D+T+++WDV +G C++ GH + F+P + +G+ D V +WD+ G
Sbjct: 103 VSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGK 162
Query: 703 MVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLWDAIKAFEDLET--DDFTTATGHIN 760
+ L H+D V ++ F+RDG ++ S S D R+WD + L+T DD +
Sbjct: 163 CLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASG-QCLKTLIDDDNPPVSFVK 221
Query: 761 LPENSQELLLGT 772
N + +L T
Sbjct: 222 FSPNGKYILAAT 233
Score = 89.4 bits (220), Expect = 1e-17
Identities = 49/174 (28%), Positives = 86/174 (49%), Gaps = 24/174 (13%)
Query: 624 AGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRF 683
AGH V+ +F PN ++A+ SAD+ +++W +G + +GHK I + +S +
Sbjct: 42 AGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNL 101
Query: 684 LATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLWDAIKA 743
L + + D + +WD+ G + LKGH++ V F+ ++ SGS D +VR+WD +K
Sbjct: 102 LVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWD-VKT 160
Query: 744 FEDLETDDFTTATGHINLPENSQELLLGTYMTKSTPVVHLHFTRRNLVLAAGAY 797
+ L+T LP +S PV +HF R ++ + +Y
Sbjct: 161 GKCLKT-----------LPAHSD------------PVSAVHFNRDGSLIVSSSY 191
Score = 68.2 bits (165), Expect = 3e-11
Identities = 50/198 (25%), Positives = 79/198 (39%), Gaps = 35/198 (17%)
Query: 462 CFYTFLNAYQGLTAVDVTDDSSLIAGGFADSTVRVWSVTPKKLRSVKQASDLSLIDKESD 521
C T ++AV D SLI D R+W D S
Sbjct: 163 CLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIW-------------------DTASG 203
Query: 522 DVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGY 581
L+ ++D+ + PV FSP+ Y+L+++ D T++LW CL Y
Sbjct: 204 QCLKTLIDD-----------DNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTY 252
Query: 582 KGH---NYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPN 638
GH Y ++ G + VSG D + +W + ++ GH V T HP
Sbjct: 253 TGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPT 312
Query: 639 SNYVATGSA--DRTVRLW 654
N +A+ + D+T++LW
Sbjct: 313 ENIIASAALENDKTIKLW 330
>gi|16554627 WD repeat domain 5 [Homo sapiens]
Length = 334
Score = 146 bits (368), Expect = 8e-35
Identities = 86/292 (29%), Positives = 147/292 (50%), Gaps = 17/292 (5%)
Query: 464 YTFLNAYQGLTAVDVTDDSSLIAGGFADSTVRVWSVTPKK-----------LRSVKQASD 512
+T + +++V + + +A AD +++W K + V +SD
Sbjct: 39 FTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSD 98
Query: 513 LSLIDKESDDVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSL 572
+L+ SDD +I D + LK L GHS V+ +F+P N ++S S D +VR+W +
Sbjct: 99 SNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDV 158
Query: 573 QTFTCLVGYKGHNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLR-IFAGHLADVN 631
+T CL H+ PV F+ G VS +D + R+W T Q L+ + V+
Sbjct: 159 KTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVS 218
Query: 632 CTRFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSL--TFS-PNGRFLATGA 688
+F PN Y+ + D T++LWD G C++ +TGHK + + FS G+++ +G+
Sbjct: 219 FVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGS 278
Query: 689 TDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDN--TVRLW 738
D V +W++ +V +L+GHTD V S I+AS +++N T++LW
Sbjct: 279 EDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLW 330
Score = 122 bits (305), Expect = 2e-27
Identities = 66/223 (29%), Positives = 106/223 (47%), Gaps = 7/223 (3%)
Query: 539 LYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPYGY 598
L GH+ V FSP+ +L SSS D +++W GH + D +S
Sbjct: 41 LAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSN 100
Query: 599 YFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLN 658
VS D+ ++W + L+ GH V C F+P SN + +GS D +VR+WDV
Sbjct: 101 LLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKT 160
Query: 659 GNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGEL-KGHTDTVCSL 717
G C++ H P+ ++ F+ +G + + + DG +WD G + L V +
Sbjct: 161 GKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFV 220
Query: 718 RFSRDGEILASGSMDNTVRLWDAIKAFEDLETDDFTTATGHIN 760
+FS +G+ + + ++DNT++LWD K T TGH N
Sbjct: 221 KFSPNGKYILAATLDNTLKLWDYSKG------KCLKTYTGHKN 257
Score = 115 bits (289), Expect = 1e-25
Identities = 68/242 (28%), Positives = 115/242 (47%), Gaps = 4/242 (1%)
Query: 502 KKLRSVKQASDLSLIDKESDDVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSS 561
K + SVK + + + S D L +I K + GH + ++S D N L+S+
Sbjct: 46 KAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSA 105
Query: 562 SEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLR 621
S+D T+++W + + CL KGH+ V+ F+P VSG D R+W + L+
Sbjct: 106 SDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLK 165
Query: 622 IFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLNGNCVR-IFTGHKGPIHSLTFSPN 680
H V+ F+ + + + + S D R+WD +G C++ + P+ + FSPN
Sbjct: 166 TLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPN 225
Query: 681 GRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSL--RFS-RDGEILASGSMDNTVRL 737
G+++ D + LWD G + GH + + FS G+ + SGS DN V +
Sbjct: 226 GKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYI 285
Query: 738 WD 739
W+
Sbjct: 286 WN 287
Score = 109 bits (272), Expect = 1e-23
Identities = 53/192 (27%), Positives = 95/192 (49%), Gaps = 3/192 (1%)
Query: 583 GHNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYV 642
GH V +FSP G + S D++ ++W + + +GH ++ + +SN +
Sbjct: 43 GHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLL 102
Query: 643 ATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGL 702
+ S D+T+++WDV +G C++ GH + F+P + +G+ D V +WD+ G
Sbjct: 103 VSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGK 162
Query: 703 MVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLWDAIKAFEDLET--DDFTTATGHIN 760
+ L H+D V ++ F+RDG ++ S S D R+WD + L+T DD +
Sbjct: 163 CLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASG-QCLKTLIDDDNPPVSFVK 221
Query: 761 LPENSQELLLGT 772
N + +L T
Sbjct: 222 FSPNGKYILAAT 233
Score = 89.4 bits (220), Expect = 1e-17
Identities = 49/174 (28%), Positives = 86/174 (49%), Gaps = 24/174 (13%)
Query: 624 AGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRF 683
AGH V+ +F PN ++A+ SAD+ +++W +G + +GHK I + +S +
Sbjct: 42 AGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNL 101
Query: 684 LATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLWDAIKA 743
L + + D + +WD+ G + LKGH++ V F+ ++ SGS D +VR+WD +K
Sbjct: 102 LVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWD-VKT 160
Query: 744 FEDLETDDFTTATGHINLPENSQELLLGTYMTKSTPVVHLHFTRRNLVLAAGAY 797
+ L+T LP +S PV +HF R ++ + +Y
Sbjct: 161 GKCLKT-----------LPAHSD------------PVSAVHFNRDGSLIVSSSY 191
Score = 68.2 bits (165), Expect = 3e-11
Identities = 50/198 (25%), Positives = 79/198 (39%), Gaps = 35/198 (17%)
Query: 462 CFYTFLNAYQGLTAVDVTDDSSLIAGGFADSTVRVWSVTPKKLRSVKQASDLSLIDKESD 521
C T ++AV D SLI D R+W D S
Sbjct: 163 CLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIW-------------------DTASG 203
Query: 522 DVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGY 581
L+ ++D+ + PV FSP+ Y+L+++ D T++LW CL Y
Sbjct: 204 QCLKTLIDD-----------DNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTY 252
Query: 582 KGH---NYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPN 638
GH Y ++ G + VSG D + +W + ++ GH V T HP
Sbjct: 253 TGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPT 312
Query: 639 SNYVATGSA--DRTVRLW 654
N +A+ + D+T++LW
Sbjct: 313 ENIIASAALENDKTIKLW 330
>gi|23199987 WD repeat domain 5B [Homo sapiens]
Length = 330
Score = 144 bits (364), Expect = 2e-34
Identities = 85/291 (29%), Positives = 147/291 (50%), Gaps = 17/291 (5%)
Query: 465 TFLNAYQGLTAVDVTDDSSLIAGGFADSTVRVWSVTPKK-----------LRSVKQASDL 513
T + + +++V + + +A AD + +W K + V +SD
Sbjct: 36 TLVGHTEAVSSVKFSPNGEWLASSSADRLIIIWGAYDGKYEKTLYGHNLEISDVAWSSDS 95
Query: 514 SLIDKESDDVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQ 573
S + SDD ++ D ++ LK L GHS V+ +F+P N ++S S D TV++W ++
Sbjct: 96 SRLVSASDDKTLKLWDVRSGKCLKTLKGHSNYVFCCNFNPPSNLIISGSFDETVKIWEVK 155
Query: 574 TFTCLVGYKGHNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLR-IFAGHLADVNC 632
T CL H+ PV F+ G VSG +D + R+W Q L+ + V+
Sbjct: 156 TGKCLKTLSAHSDPVSAVHFNCSGSLIVSGSYDGLCRIWDAASGQCLKTLVDDDNPPVSF 215
Query: 633 TRFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSL--TFS-PNGRFLATGAT 689
+F PN Y+ T + D T++LWD G C++ +TGHK + + FS G+++ +G+
Sbjct: 216 VKFSPNGKYILTATLDNTLKLWDYSRGRCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSE 275
Query: 690 DGRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDN--TVRLW 738
D V +W++ +V +L+GHTD V S ++AS +++N T++LW
Sbjct: 276 DNLVYIWNLQTKEIVQKLQGHTDVVISAACHPTENLIASAALENDKTIKLW 326
Score = 119 bits (299), Expect = 8e-27
Identities = 69/238 (28%), Positives = 118/238 (49%), Gaps = 4/238 (1%)
Query: 506 SVKQASDLSLIDKESDDVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDG 565
SVK + + + S D L I K LYGH+ + ++S D + L+S+S+D
Sbjct: 46 SVKFSPNGEWLASSSADRLIIIWGAYDGKYEKTLYGHNLEISDVAWSSDSSRLVSASDDK 105
Query: 566 TVRLWSLQTFTCLVGYKGHNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAG 625
T++LW +++ CL KGH+ V+ F+P +SG D ++W + L+ +
Sbjct: 106 TLKLWDVRSGKCLKTLKGHSNYVFCCNFNPPSNLIISGSFDETVKIWEVKTGKCLKTLSA 165
Query: 626 HLADVNCTRFHPNSNYVATGSADRTVRLWDVLNGNCVR-IFTGHKGPIHSLTFSPNGRFL 684
H V+ F+ + + + +GS D R+WD +G C++ + P+ + FSPNG+++
Sbjct: 166 HSDPVSAVHFNCSGSLIVSGSYDGLCRIWDAASGQCLKTLVDDDNPPVSFVKFSPNGKYI 225
Query: 685 ATGATDGRVLLWDIGHGLMVGELKGHTDTVCSL--RFS-RDGEILASGSMDNTVRLWD 739
T D + LWD G + GH + + FS G+ + SGS DN V +W+
Sbjct: 226 LTATLDNTLKLWDYSRGRCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWN 283
Score = 103 bits (256), Expect = 8e-22
Identities = 53/192 (27%), Positives = 94/192 (48%), Gaps = 3/192 (1%)
Query: 583 GHNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYV 642
GH V +FSP G + S DR+ +W + + GH +++ + +S+ +
Sbjct: 39 GHTEAVSSVKFSPNGEWLASSSADRLIIIWGAYDGKYEKTLYGHNLEISDVAWSSDSSRL 98
Query: 643 ATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGL 702
+ S D+T++LWDV +G C++ GH + F+P + +G+ D V +W++ G
Sbjct: 99 VSASDDKTLKLWDVRSGKCLKTLKGHSNYVFCCNFNPPSNLIISGSFDETVKIWEVKTGK 158
Query: 703 MVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLWDAIKAFEDLET--DDFTTATGHIN 760
+ L H+D V ++ F+ G ++ SGS D R+WDA + L+T DD +
Sbjct: 159 CLKTLSAHSDPVSAVHFNCSGSLIVSGSYDGLCRIWDAASG-QCLKTLVDDDNPPVSFVK 217
Query: 761 LPENSQELLLGT 772
N + +L T
Sbjct: 218 FSPNGKYILTAT 229
Score = 66.2 bits (160), Expect = 1e-10
Identities = 49/198 (24%), Positives = 78/198 (39%), Gaps = 35/198 (17%)
Query: 462 CFYTFLNAYQGLTAVDVTDDSSLIAGGFADSTVRVWSVTPKKLRSVKQASDLSLIDKESD 521
C T ++AV SLI G D R+W D S
Sbjct: 159 CLKTLSAHSDPVSAVHFNCSGSLIVSGSYDGLCRIW-------------------DAASG 199
Query: 522 DVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGY 581
L+ ++D+ + PV FSP+ Y+L+++ D T++LW CL Y
Sbjct: 200 QCLKTLVDD-----------DNPPVSFVKFSPNGKYILTATLDNTLKLWDYSRGRCLKTY 248
Query: 582 KGH---NYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPN 638
GH Y ++ G + VSG D + +W + ++ GH V HP
Sbjct: 249 TGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISAACHPT 308
Query: 639 SNYVATGSA--DRTVRLW 654
N +A+ + D+T++LW
Sbjct: 309 ENLIASAALENDKTIKLW 326
Score = 37.7 bits (86), Expect = 0.042
Identities = 17/34 (50%), Positives = 23/34 (67%)
Query: 707 LKGHTDTVCSLRFSRDGEILASGSMDNTVRLWDA 740
L GHT+ V S++FS +GE LAS S D + +W A
Sbjct: 37 LVGHTEAVSSVKFSPNGEWLASSSADRLIIIWGA 70
>gi|113865883 WD repeat domain 38 [Homo sapiens]
Length = 314
Score = 137 bits (346), Expect = 3e-32
Identities = 78/206 (37%), Positives = 107/206 (51%), Gaps = 4/206 (1%)
Query: 536 LKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSP 595
+K H G V ++FSPD LL+ SEDG V W ++ L GH PV +FSP
Sbjct: 14 VKFFGQHGGEVNSSAFSPDGQMLLTGSEDGCVYGWETRSGQLLWRLGGHTGPVKFCRFSP 73
Query: 596 YGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWD 655
G+ F S D RLW + LR+ GH V F P+S +A+G D+ V LWD
Sbjct: 74 DGHLFASASCDCTVRLWDVARAKCLRVLKGHQRSVETVSFSPDSRQLASGGWDKRVMLWD 133
Query: 656 VLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWD---IGHGLMVGELKGHTD 712
V +G +R+ GH+ I S FSP LATG+ D V +WD + + L+GH+
Sbjct: 134 VQSGQMLRLLVGHRDSIQSSDFSPTVNCLATGSWDSTVHIWDLRMVTPAVSHQALEGHSA 193
Query: 713 TVCSLRFSRDGEILASGSMDNTVRLW 738
+ L +S G +LASGS D T+ +W
Sbjct: 194 NISCLCYSASG-LLASGSWDKTIHIW 218
Score = 121 bits (303), Expect = 3e-27
Identities = 63/156 (40%), Positives = 86/156 (55%)
Query: 584 HNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVA 643
H V + FSP G ++G D W T Q L GH V RF P+ + A
Sbjct: 20 HGGEVNSSAFSPDGQMLLTGSEDGCVYGWETRSGQLLWRLGGHTGPVKFCRFSPDGHLFA 79
Query: 644 TGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLM 703
+ S D TVRLWDV C+R+ GH+ + +++FSP+ R LA+G D RV+LWD+ G M
Sbjct: 80 SASCDCTVRLWDVARAKCLRVLKGHQRSVETVSFSPDSRQLASGGWDKRVMLWDVQSGQM 139
Query: 704 VGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLWD 739
+ L GH D++ S FS LA+GS D+TV +WD
Sbjct: 140 LRLLVGHRDSIQSSDFSPTVNCLATGSWDSTVHIWD 175
Score = 109 bits (273), Expect = 9e-24
Identities = 74/242 (30%), Positives = 99/242 (40%), Gaps = 44/242 (18%)
Query: 539 LYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPYGY 598
L GH+GPV FSPD + S+S D TVRLW + CL KGH V FSP
Sbjct: 59 LGGHTGPVKFCRFSPDGHLFASASCDCTVRLWDVARAKCLRVLKGHQRSVETVSFSPDSR 118
Query: 599 YFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSAD---------- 648
SGG D+ LW Q LR+ GH + + F P N +ATGS D
Sbjct: 119 QLASGGWDKRVMLWDVQSGQMLRLLVGHRDSIQSSDFSPTVNCLATGSWDSTVHIWDLRM 178
Query: 649 ----------------------------------RTVRLWDVLNGNCVRIFTGHKGPIHS 674
+T+ +W + + GH + S
Sbjct: 179 VTPAVSHQALEGHSANISCLCYSASGLLASGSWDKTIHIWKPTTSSLLIQLKGHVTWVKS 238
Query: 675 LTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNT 734
+ FSP+ +LA+ V +WD G + LKG D + F+ DG+IL SG+ D T
Sbjct: 239 IAFSPDELWLASAGYSRMVKVWDCNTGKCLETLKGVLDVAHTCAFTPDGKILVSGAADQT 298
Query: 735 VR 736
R
Sbjct: 299 RR 300
Score = 87.0 bits (214), Expect = 6e-17
Identities = 46/127 (36%), Positives = 65/127 (51%)
Query: 613 ATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPI 672
AT + ++ F H +VN + F P+ + TGS D V W+ +G + GH GP+
Sbjct: 7 ATLAVRRVKFFGQHGGEVNSSAFSPDGQMLLTGSEDGCVYGWETRSGQLLWRLGGHTGPV 66
Query: 673 HSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMD 732
FSP+G A+ + D V LWD+ + LKGH +V ++ FS D LASG D
Sbjct: 67 KFCRFSPDGHLFASASCDCTVRLWDVARAKCLRVLKGHQRSVETVSFSPDSRQLASGGWD 126
Query: 733 NTVRLWD 739
V LWD
Sbjct: 127 KRVMLWD 133
Score = 75.5 bits (184), Expect = 2e-13
Identities = 38/82 (46%), Positives = 49/82 (59%)
Query: 662 VRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSR 721
V+ F H G ++S FSP+G+ L TG+ DG V W+ G ++ L GHT V RFS
Sbjct: 14 VKFFGQHGGEVNSSAFSPDGQMLLTGSEDGCVYGWETRSGQLLWRLGGHTGPVKFCRFSP 73
Query: 722 DGEILASGSMDNTVRLWDAIKA 743
DG + AS S D TVRLWD +A
Sbjct: 74 DGHLFASASCDCTVRLWDVARA 95
>gi|83779014 katanin p80 subunit B 1 [Homo sapiens]
Length = 655
Score = 137 bits (345), Expect = 4e-32
Identities = 74/213 (34%), Positives = 109/213 (51%), Gaps = 1/213 (0%)
Query: 531 KTASELKILYGHSGPVYGASFSPDRNYLLSSS-EDGTVRLWSLQTFTCLVGYKGHNYPVW 589
KTA +L+ + H+ V LL++ +D V LWS+ C++ GH PV
Sbjct: 8 KTAWKLQEIVAHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVE 67
Query: 590 DTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADR 649
+ + V+G R+W + + LR GH A++ FHP +VA+GS D
Sbjct: 68 SVRLNTPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDT 127
Query: 650 TVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKG 709
++LWD+ CV + GH + L FSP+G++LA+ A D V LWD+ G M+ E G
Sbjct: 128 NIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPG 187
Query: 710 HTDTVCSLRFSRDGEILASGSMDNTVRLWDAIK 742
HT V + F + +LASGS D T+R WD K
Sbjct: 188 HTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEK 220
Score = 125 bits (315), Expect = 1e-28
Identities = 65/208 (31%), Positives = 105/208 (50%), Gaps = 1/208 (0%)
Query: 539 LYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPYGY 598
L GH+ PV + +++ S+ G++R+W L+ L GH + F PYG
Sbjct: 59 LTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGE 118
Query: 599 YFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLN 658
+ SG D +LW + + GH V C RF P+ ++A+ + D TV+LWD+
Sbjct: 119 FVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTA 178
Query: 659 GNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLR 718
G + F GH GP++ + F PN LA+G++D + WD+ +V ++G V S+
Sbjct: 179 GKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCIEGEPGPVRSVL 238
Query: 719 FSRDGEILASGSMDN-TVRLWDAIKAFE 745
F+ DG L SG D+ V W+ + F+
Sbjct: 239 FNPDGCCLYSGCQDSLRVYGWEPERCFD 266
Score = 124 bits (311), Expect = 3e-28
Identities = 71/226 (31%), Positives = 107/226 (47%), Gaps = 12/226 (5%)
Query: 484 LIAGGFADSTVRVWSVTPKK-----------LRSVKQASDLSLIDKESDDVLERIMDEKT 532
L+A G D V +WS+ + SV+ + LI S R+ D +
Sbjct: 35 LLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEA 94
Query: 533 ASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQ 592
A L+ L GH + F P ++ S S+D ++LW ++ C+ Y+GH+ V +
Sbjct: 95 AKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLR 154
Query: 593 FSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVR 652
FSP G + S D +LW + + F GH VN FHPN +A+GS+DRT+R
Sbjct: 155 FSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIR 214
Query: 653 LWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDG-RVLLWD 697
WD+ V G GP+ S+ F+P+G L +G D RV W+
Sbjct: 215 FWDLEKFQVVSCIEGEPGPVRSVLFNPDGCCLYSGCQDSLRVYGWE 260
Score = 52.0 bits (123), Expect = 2e-06
Identities = 36/145 (24%), Positives = 53/145 (36%), Gaps = 31/145 (21%)
Query: 462 CFYTFLNAYQGLTAVDVTDDSSLIAGGFADSTVRVWSVTPKKLRSVKQASDLSLIDKESD 521
C + + Q + + + D +A D TV++W +T K+ S
Sbjct: 139 CVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSE-------------- 184
Query: 522 DVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGY 581
GH+GPV F P+ L S S D T+R W L+ F +
Sbjct: 185 -----------------FPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCI 227
Query: 582 KGHNYPVWDTQFSPYGYYFVSGGHD 606
+G PV F+P G SG D
Sbjct: 228 EGEPGPVRSVLFNPDGCCLYSGCQD 252
>gi|26665869 WD repeat domain 51B [Homo sapiens]
Length = 478
Score = 136 bits (343), Expect = 7e-32
Identities = 75/277 (27%), Positives = 140/277 (50%), Gaps = 11/277 (3%)
Query: 473 LTAVDVTDDSSLIAGGFADSTVRVWSVTPKK-----------LRSVKQASDLSLIDKESD 521
+T++D++ + +A D+ + +W+ P + SV+ + +L+ S
Sbjct: 21 ITSLDLSPNGKQLATASWDTFLMLWNFKPHARAYRYVGHKDVVTSVQFSPHGNLLASASR 80
Query: 522 DVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGY 581
D R+ + H+ PV FS D +L ++SED ++++WS+ L
Sbjct: 81 DRTVRLWIPDKRGKFSEFKAHTAPVRSVDFSADGQFLATASEDKSIKVWSMYRQRFLYSL 140
Query: 582 KGHNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNY 641
H + V +FSP G VS D+ ++W T + Q + F+ + N F+P+
Sbjct: 141 YRHTHWVRCAKFSPDGRLIVSCSEDKTIKIWDTTNKQCVNNFSDSVGFANFVDFNPSGTC 200
Query: 642 VATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHG 701
+A+ +D+TV++WDV ++ + H G ++ ++F P+G +L T ++DG + + D+ G
Sbjct: 201 IASAGSDQTVKVWDVRVNKLLQHYQVHSGGVNCISFHPSGNYLITASSDGTLKILDLLEG 260
Query: 702 LMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLW 738
++ L+GHT V ++ FS+ GE+ ASG D V LW
Sbjct: 261 RLIYTLQGHTGPVFTVSFSKGGELFASGGADTQVLLW 297
Score = 102 bits (254), Expect = 1e-21
Identities = 54/199 (27%), Positives = 85/199 (42%)
Query: 541 GHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPYGYYF 600
GH + SP+ L ++S D + LW+ + Y GH V QFSP+G
Sbjct: 16 GHKAAITSLDLSPNGKQLATASWDTFLMLWNFKPHARAYRYVGHKDVVTSVQFSPHGNLL 75
Query: 601 VSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLNGN 660
S DR RLW D F H A V F + ++AT S D+++++W +
Sbjct: 76 ASASRDRTVRLWIPDKRGKFSEFKAHTAPVRSVDFSADGQFLATASEDKSIKVWSMYRQR 135
Query: 661 CVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFS 720
+ H + FSP+GR + + + D + +WD + V + F+
Sbjct: 136 FLYSLYRHTHWVRCAKFSPDGRLIVSCSEDKTIKIWDTTNKQCVNNFSDSVGFANFVDFN 195
Query: 721 RDGEILASGSMDNTVRLWD 739
G +AS D TV++WD
Sbjct: 196 PSGTCIASAGSDQTVKVWD 214
Score = 96.3 bits (238), Expect = 1e-19
Identities = 51/159 (32%), Positives = 75/159 (47%)
Query: 581 YKGHNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSN 640
+KGH + SP G + D LW + + GH V +F P+ N
Sbjct: 14 FKGHKAAITSLDLSPNGKQLATASWDTFLMLWNFKPHARAYRYVGHKDVVTSVQFSPHGN 73
Query: 641 YVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGH 700
+A+ S DRTVRLW F H P+ S+ FS +G+FLAT + D + +W +
Sbjct: 74 LLASASRDRTVRLWIPDKRGKFSEFKAHTAPVRSVDFSADGQFLATASEDKSIKVWSMYR 133
Query: 701 GLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLWD 739
+ L HT V +FS DG ++ S S D T+++WD
Sbjct: 134 QRFLYSLYRHTHWVRCAKFSPDGRLIVSCSEDKTIKIWD 172
Score = 77.4 bits (189), Expect = 5e-14
Identities = 42/118 (35%), Positives = 59/118 (50%)
Query: 621 RIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPN 680
R F GH A + PN +AT S D + LW+ + GHK + S+ FSP+
Sbjct: 12 RYFKGHKAAITSLDLSPNGKQLATASWDTFLMLWNFKPHARAYRYVGHKDVVTSVQFSPH 71
Query: 681 GRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLW 738
G LA+ + D V LW E K HT V S+ FS DG+ LA+ S D ++++W
Sbjct: 72 GNLLASASRDRTVRLWIPDKRGKFSEFKAHTAPVRSVDFSADGQFLATASEDKSIKVW 129
Score = 67.0 bits (162), Expect = 7e-11
Identities = 45/148 (30%), Positives = 64/148 (43%), Gaps = 15/148 (10%)
Query: 481 DSSLIAGGFADSTVRVWSVTPKKLRSVKQASDL-------------SLIDKESDDVLERI 527
D LI D T+++W T K+ V SD + I D ++
Sbjct: 155 DGRLIVSCSEDKTIKIWDTTNKQC--VNNFSDSVGFANFVDFNPSGTCIASAGSDQTVKV 212
Query: 528 MDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYP 587
D + L+ HSG V SF P NYL+++S DGT+++ L + +GH P
Sbjct: 213 WDVRVNKLLQHYQVHSGGVNCISFHPSGNYLITASSDGTLKILDLLEGRLIYTLQGHTGP 272
Query: 588 VWDTQFSPYGYYFVSGGHDRVARLWATD 615
V+ FS G F SGG D LW T+
Sbjct: 273 VFTVSFSKGGELFASGGADTQVLLWRTN 300
>gi|32189425 WD repeat domain 69 [Homo sapiens]
Length = 415
Score = 135 bits (341), Expect = 1e-31
Identities = 72/205 (35%), Positives = 108/205 (52%), Gaps = 1/205 (0%)
Query: 537 KILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQF-SP 595
K+L H P+ + + + ++ S D T +LW + L +GH V+ F +P
Sbjct: 86 KVLKAHILPLTNVALNKSGSCFITGSYDRTCKLWDTASGEELNTLEGHRNVVYAIAFNNP 145
Query: 596 YGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWD 655
YG +G D+ +LW+ + + F GH A++ C F+P S VATGS D T +LWD
Sbjct: 146 YGDKIATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWD 205
Query: 656 VLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVC 715
+ NG V GH I SL+F+ +G + TG+ D V++WD G V L GH +
Sbjct: 206 IQNGEEVYTLRGHSAEIISLSFNTSGDRIITGSFDHTVVVWDADTGRKVNILIGHCAEIS 265
Query: 716 SLRFSRDGEILASGSMDNTVRLWDA 740
S F+ D ++ +GSMD T +LWDA
Sbjct: 266 SASFNWDCSLILTGSMDKTCKLWDA 290
Score = 127 bits (320), Expect = 3e-29
Identities = 76/280 (27%), Positives = 124/280 (44%), Gaps = 12/280 (4%)
Query: 473 LTAVDVTDDSSLIAGGFADSTVRVWSV-------TPKKLRSVKQASDLS-----LIDKES 520
LT V + S G D T ++W T + R+V A + I S
Sbjct: 95 LTNVALNKSGSCFITGSYDRTCKLWDTASGEELNTLEGHRNVVYAIAFNNPYGDKIATGS 154
Query: 521 DDVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVG 580
D ++ +T GH+ + SF+P + + S D T +LW +Q +
Sbjct: 155 FDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDIQNGEEVYT 214
Query: 581 YKGHNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSN 640
+GH+ + F+ G ++G D +W D + + I GH A+++ F+ + +
Sbjct: 215 LRGHSAEIISLSFNTSGDRIITGSFDHTVVVWDADTGRKVNILIGHCAEISSASFNWDCS 274
Query: 641 YVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGH 700
+ TGS D+T +LWD NG CV TGH I F G+ +AT + DG ++
Sbjct: 275 LILTGSMDKTCKLWDATNGKCVATLTGHDDEILDSCFDYTGKLIATASADGTARIFSAAT 334
Query: 701 GLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLWDA 740
+ +L+GH + + F+ G L +GS D T R+WDA
Sbjct: 335 RKCIAKLEGHEGEISKISFNPQGNHLLTGSSDKTARIWDA 374
Score = 118 bits (295), Expect = 2e-26
Identities = 63/171 (36%), Positives = 90/171 (52%), Gaps = 1/171 (0%)
Query: 571 SLQTFTCLVGYKGHNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADV 630
S TF K H P+ + + G F++G +DR +LW T + L GH V
Sbjct: 78 SNHTFYLFKVLKAHILPLTNVALNKSGSCFITGSYDRTCKLWDTASGEELNTLEGHRNVV 137
Query: 631 NCTRF-HPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGAT 689
F +P + +ATGS D+T +LW V G C F GH I L+F+P +ATG+
Sbjct: 138 YAIAFNNPYGDKIATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSM 197
Query: 690 DGRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLWDA 740
D LWDI +G V L+GH+ + SL F+ G+ + +GS D+TV +WDA
Sbjct: 198 DTTAKLWDIQNGEEVYTLRGHSAEIISLSFNTSGDRIITGSFDHTVVVWDA 248
Score = 117 bits (294), Expect = 3e-26
Identities = 63/246 (25%), Positives = 113/246 (45%), Gaps = 11/246 (4%)
Query: 462 CFYTFLNAYQGLTAVDVTDDSSLIAGGFADSTVRVWSVTPKKLRSVKQASDLSLIDKESD 521
C++TF + + S+L+A G D+T ++W + + + +I +
Sbjct: 169 CYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDIQNGEEVYTLRGHSAEIISLSFN 228
Query: 522 DVLERIM-----------DEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLW 570
+RI+ D T ++ IL GH + ASF+ D + +L+ S D T +LW
Sbjct: 229 TSGDRIITGSFDHTVVVWDADTGRKVNILIGHCAEISSASFNWDCSLILTGSMDKTCKLW 288
Query: 571 SLQTFTCLVGYKGHNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADV 630
C+ GH+ + D+ F G + D AR+++ + + GH ++
Sbjct: 289 DATNGKCVATLTGHDDEILDSCFDYTGKLIATASADGTARIFSAATRKCIAKLEGHEGEI 348
Query: 631 NCTRFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATD 690
+ F+P N++ TGS+D+T R+WD G C+++ GH I S F+ G + TG+ D
Sbjct: 349 SKISFNPQGNHLLTGSSDKTARIWDAQTGQCLQVLEGHTDEIFSCAFNYKGNIVITGSKD 408
Query: 691 GRVLLW 696
+W
Sbjct: 409 NTCRIW 414
Score = 31.2 bits (69), Expect = 4.0
Identities = 15/55 (27%), Positives = 25/55 (45%), Gaps = 6/55 (10%)
Query: 707 LKGHTDTVCSLRFSRDGEILASGSMDNTVRLWDAIKAFEDLETDDFTTATGHINL 761
LK H + ++ ++ G +GS D T +LWD ++ T GH N+
Sbjct: 88 LKAHILPLTNVALNKSGSCFITGSYDRTCKLWDTASG------EELNTLEGHRNV 136
>gi|239787764 WD repeat domain 51A isoform 3 [Homo sapiens]
Length = 369
Score = 126 bits (317), Expect = 7e-29
Identities = 75/244 (30%), Positives = 115/244 (47%), Gaps = 11/244 (4%)
Query: 464 YTFLNAYQGLTAVDVTDDSSLIAGGFADSTVRVWSVTPK-----------KLRSVKQASD 512
Y F +T V+ + L+A G D TVR+W K +RSV SD
Sbjct: 17 YRFTGHKDAVTCVNFSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSD 76
Query: 513 LSLIDKESDDVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSL 572
SDD ++ L L H V A FSPD ++S+S+D TV+LW
Sbjct: 77 GQSFVTASDDKTVKVWATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDK 136
Query: 573 QTFTCLVGYKGHNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNC 632
+ C+ Y H V F P G + G D ++W ++ L+ + H A VN
Sbjct: 137 SSRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHYQLHSAAVNG 196
Query: 633 TRFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGR 692
FHP+ NY+ T S+D T+++ D++ G + GH+GP ++ FS G + A+G +D +
Sbjct: 197 LSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFASGGSDEQ 256
Query: 693 VLLW 696
V++W
Sbjct: 257 VMVW 260
Score = 110 bits (275), Expect = 5e-24
Identities = 59/202 (29%), Positives = 96/202 (47%)
Query: 541 GHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPYGYYF 600
GH V +FSP + L S S D TVR+W ++ H V F G F
Sbjct: 21 GHKDAVTCVNFSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSF 80
Query: 601 VSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLNGN 660
V+ D+ ++WAT + L + H+ V C +F P+ + + S D+TV+LWD +
Sbjct: 81 VTASDDKTVKVWATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKSSRE 140
Query: 661 CVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFS 720
CV + H G + + F P+G +A D V +WD+ ++ + H+ V L F
Sbjct: 141 CVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHYQLHSAAVNGLSFH 200
Query: 721 RDGEILASGSMDNTVRLWDAIK 742
G L + S D+T+++ D ++
Sbjct: 201 PSGNYLITASSDSTLKILDLME 222
Score = 89.4 bits (220), Expect = 1e-17
Identities = 49/176 (27%), Positives = 76/176 (43%)
Query: 564 DGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIF 623
D + +W ++ + + GH V FSP G+ SG D+ R+W + +F
Sbjct: 2 DSCLMVWHMKPQSRAYRFTGHKDAVTCVNFSPSGHLLASGSRDKTVRIWVPNVKGESTVF 61
Query: 624 AGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRF 683
H A V F + T S D+TV++W + + H + FSP+GR
Sbjct: 62 RAHTATVRSVHFCSDGQSFVTASDDKTVKVWATHRQKFLFSLSQHINWVRCAKFSPDGRL 121
Query: 684 LATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLWD 739
+ + + D V LWD V H V + F G +A+ MDNTV++WD
Sbjct: 122 IVSASDDKTVKLWDKSSRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWD 177
Score = 61.6 bits (148), Expect = 3e-09
Identities = 42/154 (27%), Positives = 59/154 (38%), Gaps = 31/154 (20%)
Query: 462 CFYTFLNAYQGLTAVDVTDDSSLIAGGFADSTVRVWSVTPKKLRSVKQASDLSLIDKESD 521
C +++ +T VD + IA D+TV+VW V +L Q
Sbjct: 141 CVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHYQL----------- 189
Query: 522 DVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGY 581
HS V G SF P NYL+++S D T+++ L L
Sbjct: 190 --------------------HSAAVNGLSFHPSGNYLITASSDSTLKILDLMEGRLLYTL 229
Query: 582 KGHNYPVWDTQFSPYGYYFVSGGHDRVARLWATD 615
GH P FS G YF SGG D +W ++
Sbjct: 230 HGHQGPATTVAFSRTGEYFASGGSDEQVMVWKSN 263
>gi|239787760 WD repeat domain 51A isoform 2 [Homo sapiens]
Length = 359
Score = 126 bits (317), Expect = 7e-29
Identities = 75/244 (30%), Positives = 115/244 (47%), Gaps = 11/244 (4%)
Query: 464 YTFLNAYQGLTAVDVTDDSSLIAGGFADSTVRVWSVTPK-----------KLRSVKQASD 512
Y F +T V+ + L+A G D TVR+W K +RSV SD
Sbjct: 55 YRFTGHKDAVTCVNFSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSD 114
Query: 513 LSLIDKESDDVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSL 572
SDD ++ L L H V A FSPD ++S+S+D TV+LW
Sbjct: 115 GQSFVTASDDKTVKVWATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDK 174
Query: 573 QTFTCLVGYKGHNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNC 632
+ C+ Y H V F P G + G D ++W ++ L+ + H A VN
Sbjct: 175 SSRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHYQLHSAAVNG 234
Query: 633 TRFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGR 692
FHP+ NY+ T S+D T+++ D++ G + GH+GP ++ FS G + A+G +D +
Sbjct: 235 LSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFASGGSDEQ 294
Query: 693 VLLW 696
V++W
Sbjct: 295 VMVW 298
Score = 124 bits (310), Expect = 5e-28
Identities = 74/277 (26%), Positives = 122/277 (44%), Gaps = 11/277 (3%)
Query: 473 LTAVDVTDDSSLIAGGFADSTVRVWSVTPKK-----------LRSVKQASDLSLIDKESD 521
+T VD + ++ +A G DS + VW + P+ + V + L+ S
Sbjct: 22 VTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFSPSGHLLASGSR 81
Query: 522 DVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGY 581
D RI E + H+ V F D +++S+D TV++W+ L
Sbjct: 82 DKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVWATHRQKFLFSL 141
Query: 582 KGHNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNY 641
H V +FSP G VS D+ +LW + + + H V FHP+
Sbjct: 142 SQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKSSRECVHSYCEHGGFVTYVDFHPSGTC 201
Query: 642 VATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHG 701
+A D TV++WDV ++ + H ++ L+F P+G +L T ++D + + D+ G
Sbjct: 202 IAAAGMDNTVKVWDVRTHRLLQHYQLHSAAVNGLSFHPSGNYLITASSDSTLKILDLMEG 261
Query: 702 LMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLW 738
++ L GH ++ FSR GE ASG D V +W
Sbjct: 262 RLLYTLHGHQGPATTVAFSRTGEYFASGGSDEQVMVW 298
Score = 99.0 bits (245), Expect = 2e-20
Identities = 57/199 (28%), Positives = 85/199 (42%)
Query: 541 GHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPYGYYF 600
GH V FS + L S S D + +W ++ + + GH V FSP G+
Sbjct: 17 GHRDAVTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFSPSGHLL 76
Query: 601 VSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLNGN 660
SG D+ R+W + +F H A V F + T S D+TV++W
Sbjct: 77 ASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVWATHRQK 136
Query: 661 CVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFS 720
+ + H + FSP+GR + + + D V LWD V H V + F
Sbjct: 137 FLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKSSRECVHSYCEHGGFVTYVDFH 196
Query: 721 RDGEILASGSMDNTVRLWD 739
G +A+ MDNTV++WD
Sbjct: 197 PSGTCIAAAGMDNTVKVWD 215
Score = 85.9 bits (211), Expect = 1e-16
Identities = 49/159 (30%), Positives = 70/159 (44%)
Query: 581 YKGHNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSN 640
+KGH V FS SG D +W F GH V C F P+ +
Sbjct: 15 FKGHRDAVTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFSPSGH 74
Query: 641 YVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGH 700
+A+GS D+TVR+W +F H + S+ F +G+ T + D V +W
Sbjct: 75 LLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVWATHR 134
Query: 701 GLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLWD 739
+ L H + V +FS DG ++ S S D TV+LWD
Sbjct: 135 QKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWD 173
Score = 76.3 bits (186), Expect = 1e-13
Identities = 41/118 (34%), Positives = 60/118 (50%)
Query: 621 RIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPN 680
R F GH V C F N+ +A+GS D + +W + + FTGHK + + FSP+
Sbjct: 13 RHFKGHRDAVTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFSPS 72
Query: 681 GRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLW 738
G LA+G+ D V +W + HT TV S+ F DG+ + S D TV++W
Sbjct: 73 GHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVW 130
Score = 61.6 bits (148), Expect = 3e-09
Identities = 42/154 (27%), Positives = 59/154 (38%), Gaps = 31/154 (20%)
Query: 462 CFYTFLNAYQGLTAVDVTDDSSLIAGGFADSTVRVWSVTPKKLRSVKQASDLSLIDKESD 521
C +++ +T VD + IA D+TV+VW V +L Q
Sbjct: 179 CVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHYQL----------- 227
Query: 522 DVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGY 581
HS V G SF P NYL+++S D T+++ L L
Sbjct: 228 --------------------HSAAVNGLSFHPSGNYLITASSDSTLKILDLMEGRLLYTL 267
Query: 582 KGHNYPVWDTQFSPYGYYFVSGGHDRVARLWATD 615
GH P FS G YF SGG D +W ++
Sbjct: 268 HGHQGPATTVAFSRTGEYFASGGSDEQVMVWKSN 301
>gi|239787754 WD repeat domain 51A isoform 1 [Homo sapiens]
Length = 407
Score = 126 bits (317), Expect = 7e-29
Identities = 75/244 (30%), Positives = 115/244 (47%), Gaps = 11/244 (4%)
Query: 464 YTFLNAYQGLTAVDVTDDSSLIAGGFADSTVRVWSVTPK-----------KLRSVKQASD 512
Y F +T V+ + L+A G D TVR+W K +RSV SD
Sbjct: 55 YRFTGHKDAVTCVNFSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSD 114
Query: 513 LSLIDKESDDVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSL 572
SDD ++ L L H V A FSPD ++S+S+D TV+LW
Sbjct: 115 GQSFVTASDDKTVKVWATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDK 174
Query: 573 QTFTCLVGYKGHNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNC 632
+ C+ Y H V F P G + G D ++W ++ L+ + H A VN
Sbjct: 175 SSRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHYQLHSAAVNG 234
Query: 633 TRFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGR 692
FHP+ NY+ T S+D T+++ D++ G + GH+GP ++ FS G + A+G +D +
Sbjct: 235 LSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFASGGSDEQ 294
Query: 693 VLLW 696
V++W
Sbjct: 295 VMVW 298
Score = 124 bits (310), Expect = 5e-28
Identities = 74/277 (26%), Positives = 122/277 (44%), Gaps = 11/277 (3%)
Query: 473 LTAVDVTDDSSLIAGGFADSTVRVWSVTPKK-----------LRSVKQASDLSLIDKESD 521
+T VD + ++ +A G DS + VW + P+ + V + L+ S
Sbjct: 22 VTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFSPSGHLLASGSR 81
Query: 522 DVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGY 581
D RI E + H+ V F D +++S+D TV++W+ L
Sbjct: 82 DKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVWATHRQKFLFSL 141
Query: 582 KGHNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNY 641
H V +FSP G VS D+ +LW + + + H V FHP+
Sbjct: 142 SQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKSSRECVHSYCEHGGFVTYVDFHPSGTC 201
Query: 642 VATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHG 701
+A D TV++WDV ++ + H ++ L+F P+G +L T ++D + + D+ G
Sbjct: 202 IAAAGMDNTVKVWDVRTHRLLQHYQLHSAAVNGLSFHPSGNYLITASSDSTLKILDLMEG 261
Query: 702 LMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLW 738
++ L GH ++ FSR GE ASG D V +W
Sbjct: 262 RLLYTLHGHQGPATTVAFSRTGEYFASGGSDEQVMVW 298
Score = 99.0 bits (245), Expect = 2e-20
Identities = 57/199 (28%), Positives = 85/199 (42%)
Query: 541 GHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPYGYYF 600
GH V FS + L S S D + +W ++ + + GH V FSP G+
Sbjct: 17 GHRDAVTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFSPSGHLL 76
Query: 601 VSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLNGN 660
SG D+ R+W + +F H A V F + T S D+TV++W
Sbjct: 77 ASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVWATHRQK 136
Query: 661 CVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFS 720
+ + H + FSP+GR + + + D V LWD V H V + F
Sbjct: 137 FLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKSSRECVHSYCEHGGFVTYVDFH 196
Query: 721 RDGEILASGSMDNTVRLWD 739
G +A+ MDNTV++WD
Sbjct: 197 PSGTCIAAAGMDNTVKVWD 215
Score = 85.9 bits (211), Expect = 1e-16
Identities = 49/159 (30%), Positives = 70/159 (44%)
Query: 581 YKGHNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSN 640
+KGH V FS SG D +W F GH V C F P+ +
Sbjct: 15 FKGHRDAVTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFSPSGH 74
Query: 641 YVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGH 700
+A+GS D+TVR+W +F H + S+ F +G+ T + D V +W
Sbjct: 75 LLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVWATHR 134
Query: 701 GLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLWD 739
+ L H + V +FS DG ++ S S D TV+LWD
Sbjct: 135 QKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWD 173
Score = 76.3 bits (186), Expect = 1e-13
Identities = 41/118 (34%), Positives = 60/118 (50%)
Query: 621 RIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPN 680
R F GH V C F N+ +A+GS D + +W + + FTGHK + + FSP+
Sbjct: 13 RHFKGHRDAVTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFSPS 72
Query: 681 GRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLW 738
G LA+G+ D V +W + HT TV S+ F DG+ + S D TV++W
Sbjct: 73 GHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVW 130
Score = 61.6 bits (148), Expect = 3e-09
Identities = 42/154 (27%), Positives = 59/154 (38%), Gaps = 31/154 (20%)
Query: 462 CFYTFLNAYQGLTAVDVTDDSSLIAGGFADSTVRVWSVTPKKLRSVKQASDLSLIDKESD 521
C +++ +T VD + IA D+TV+VW V +L Q
Sbjct: 179 CVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHYQL----------- 227
Query: 522 DVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGY 581
HS V G SF P NYL+++S D T+++ L L
Sbjct: 228 --------------------HSAAVNGLSFHPSGNYLITASSDSTLKILDLMEGRLLYTL 267
Query: 582 KGHNYPVWDTQFSPYGYYFVSGGHDRVARLWATD 615
GH P FS G YF SGG D +W ++
Sbjct: 268 HGHQGPATTVAFSRTGEYFASGGSDEQVMVWKSN 301
>gi|19913371 transducin (beta)-like 1 X-linked receptor 1 [Homo
sapiens]
Length = 514
Score = 123 bits (309), Expect = 6e-28
Identities = 80/292 (27%), Positives = 128/292 (43%), Gaps = 36/292 (12%)
Query: 482 SSLIAGGFADSTVRVWSVTP-------------------------KKLRSVKQASDLSLI 516
S L+A G DST R+W+++ K + S+ S+ +L+
Sbjct: 181 SDLLASGSGDSTARIWNLSENSTSGSTQLVLRHCIREGGQDVPSNKDVTSLDWNSEGTLL 240
Query: 517 DKESDDVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFT 576
S D RI K + L H GP++ ++ N++LS+ D T +W T
Sbjct: 241 ATGSYDGFARIW-TKDGNLASTLGQHKGPIFALKWNKKGNFILSAGVDKTTIIWDAHTGE 299
Query: 577 CLVGYKGHNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFH 636
+ H+ P D + F S D + +P++ F GH +VN ++
Sbjct: 300 AKQQFPFHSAPALDVDWQS-NNTFASCSTDMCIHVCKLGQDRPIKTFQGHTNEVNAIKWD 358
Query: 637 PNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNG---------RFLATG 687
P N +A+ S D T+++W + NCV H I+++ +SP G LA+
Sbjct: 359 PTGNLLASCSDDMTLKIWSMKQDNCVHDLQAHNKEIYTIKWSPTGPGTNNPNANLMLASA 418
Query: 688 ATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLWD 739
+ D V LWD+ G+ + L H + V S+ FS DG LASGS D V +W+
Sbjct: 419 SFDSTVRLWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLASGSFDKCVHIWN 470
Score = 79.3 bits (194), Expect = 1e-14
Identities = 51/215 (23%), Positives = 94/215 (43%), Gaps = 16/215 (7%)
Query: 538 ILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQ----------TFTCLVGYKGHNYP 587
+L GH V+ +++P + L S S D T R+W+L + G + P
Sbjct: 164 VLRGHESEVFICAWNPVSDLLASGSGDSTARIWNLSENSTSGSTQLVLRHCIREGGQDVP 223
Query: 588 ----VWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVA 643
V ++ G +G +D AR+W D H + +++ N++
Sbjct: 224 SNKDVTSLDWNSEGTLLATGSYDGFARIWTKDG-NLASTLGQHKGPIFALKWNKKGNFIL 282
Query: 644 TGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLM 703
+ D+T +WD G + F H P + + N F A+ +TD + + +G
Sbjct: 283 SAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQSNNTF-ASCSTDMCIHVCKLGQDRP 341
Query: 704 VGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLW 738
+ +GHT+ V ++++ G +LAS S D T+++W
Sbjct: 342 IKTFQGHTNEVNAIKWDPTGNLLASCSDDMTLKIW 376
Score = 30.8 bits (68), Expect = 5.2
Identities = 23/91 (25%), Positives = 43/91 (47%), Gaps = 10/91 (10%)
Query: 707 LKGHTDTVCSLRFSRDGEILASGSMDNTVRLWDAIKAFEDLETDDFTTATGHINLPENSQ 766
L+GH V ++ ++LASGS D+T R+W+ +++ T+ + + L +
Sbjct: 165 LRGHESEVFICAWNPVSDLLASGSGDSTARIWNL--------SENSTSGSTQLVLRHCIR 216
Query: 767 ELLLGTYMTKSTPVVHLHFTRRNLVLAAGAY 797
E G + + V L + +LA G+Y
Sbjct: 217 E--GGQDVPSNKDVTSLDWNSEGTLLATGSY 245
>gi|61743926 F-box and WD repeat domain containing 7 isoform 3 [Homo
sapiens]
Length = 589
Score = 118 bits (295), Expect = 2e-26
Identities = 75/227 (33%), Positives = 116/227 (51%), Gaps = 19/227 (8%)
Query: 537 KILYGHSGPVYGA-SFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSP 595
K+L GH V F +R ++S S+D T+++WS T CL GH VW +Q
Sbjct: 256 KVLKGHDDHVITCLQFCGNR--IVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQMR- 312
Query: 596 YGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWD 655
+SG DR ++W + + + GH + V C H V +GS D T+R+WD
Sbjct: 313 -DNIIISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHLH--EKRVVSGSRDATLRVWD 369
Query: 656 VLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVC 715
+ G C+ + GH + + + +GR + +GA D V +WD + L+GHT+ V
Sbjct: 370 IETGQCLHVLMGHVAAVRCVQY--DGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVY 427
Query: 716 SLRFSRDGEILASGSMDNTVRLWDAIKAFEDLETDD-FTTATGHINL 761
SL+F DG + SGS+D ++R+W D+ET + T TGH +L
Sbjct: 428 SLQF--DGIHVVSGSLDTSIRVW-------DVETGNCIHTLTGHQSL 465
Score = 117 bits (293), Expect = 4e-26
Identities = 84/268 (31%), Positives = 130/268 (48%), Gaps = 24/268 (8%)
Query: 485 IAGGFADSTVRVWS-VTPKKLRSV---------KQASDLSLIDKESDDVLERIMDEKTAS 534
I G D+T++VWS VT K LR++ Q D +I +D L ++ + +T
Sbjct: 276 IVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQMRDNIIISGSTDRTL-KVWNAETGE 334
Query: 535 ELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFS 594
+ LYGH+ V R ++S S D T+R+W ++T CL GH V Q+
Sbjct: 335 CIHTLYGHTSTVRCMHLHEKR--VVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQYD 392
Query: 595 PYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLW 654
G VSG +D + ++W + L GH V +F + +V +GS D ++R+W
Sbjct: 393 --GRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQF--DGIHVVSGSLDTSIRVW 448
Query: 655 DVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKG---HT 711
DV GNC+ TGH+ + N L +G D V +WDI G + L+G H
Sbjct: 449 DVETGNCIHTLTGHQSLTSGMELKDN--ILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQ 506
Query: 712 DTVCSLRFSRDGEILASGSMDNTVRLWD 739
V L+F+++ + + S D TV+LWD
Sbjct: 507 SAVTCLQFNKN--FVITSSDDGTVKLWD 532
Score = 97.8 bits (242), Expect = 3e-20
Identities = 80/290 (27%), Positives = 132/290 (45%), Gaps = 27/290 (9%)
Query: 462 CFYTFLNAYQGLTAVDVTDDSSLIAGGFADSTVRVWSV-TPKKLRSVKQASD----LSLI 516
C T + G+ + + D+ +I G D T++VW+ T + + ++ + + L
Sbjct: 295 CLRTLVGHTGGVWSSQMRDN--IIISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHLH 352
Query: 517 DKE----SDDVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSL 572
+K S D R+ D +T L +L GH V + D ++S + D V++W
Sbjct: 353 EKRVVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQY--DGRRVVSGAYDFMVKVWDP 410
Query: 573 QTFTCLVGYKGHNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNC 632
+T TCL +GH V+ QF G + VSG D R+W + + GH + +
Sbjct: 411 ETETCLHTLQGHTNRVYSLQFD--GIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSG 468
Query: 633 TRFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTG---HKGPIHSLTFSPNGRFLATGAT 689
N + +G+AD TV++WD+ G C++ G H+ + L F+ N F+ T +
Sbjct: 469 MEL--KDNILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKN--FVITSSD 524
Query: 690 DGRVLLWDIGHG-----LMVGELKGHTDTVCSLRFSRDGEILASGSMDNT 734
DG V LWD+ G L+ E G V +R S + A GS + T
Sbjct: 525 DGTVKLWDLKTGEFIRNLVTLESGGSGGVVWRIRASNTKLVCAVGSRNGT 574
Score = 68.6 bits (166), Expect = 2e-11
Identities = 40/134 (29%), Positives = 65/134 (48%), Gaps = 7/134 (5%)
Query: 607 RVARLWATDHYQPLRIFAGHLADV-NCTRFHPNSNYVATGSADRTVRLWDVLNGNCVRIF 665
R+ W + ++ GH V C +F N + +GS D T+++W + G C+R
Sbjct: 242 RIDTNWRRGELKSPKVLKGHDDHVITCLQFC--GNRIVSGSDDNTLKVWSAVTGKCLRTL 299
Query: 666 TGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDGEI 725
GH G + S N + +G+TD + +W+ G + L GHT TV + +
Sbjct: 300 VGHTGGVWSSQMRDN--IIISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHLHE--KR 355
Query: 726 LASGSMDNTVRLWD 739
+ SGS D T+R+WD
Sbjct: 356 VVSGSRDATLRVWD 369
>gi|16117781 F-box and WD repeat domain containing 7 isoform 1 [Homo
sapiens]
Length = 707
Score = 118 bits (295), Expect = 2e-26
Identities = 75/227 (33%), Positives = 116/227 (51%), Gaps = 19/227 (8%)
Query: 537 KILYGHSGPVYGA-SFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSP 595
K+L GH V F +R ++S S+D T+++WS T CL GH VW +Q
Sbjct: 374 KVLKGHDDHVITCLQFCGNR--IVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQMR- 430
Query: 596 YGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWD 655
+SG DR ++W + + + GH + V C H V +GS D T+R+WD
Sbjct: 431 -DNIIISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHLH--EKRVVSGSRDATLRVWD 487
Query: 656 VLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVC 715
+ G C+ + GH + + + +GR + +GA D V +WD + L+GHT+ V
Sbjct: 488 IETGQCLHVLMGHVAAVRCVQY--DGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVY 545
Query: 716 SLRFSRDGEILASGSMDNTVRLWDAIKAFEDLETDD-FTTATGHINL 761
SL+F DG + SGS+D ++R+W D+ET + T TGH +L
Sbjct: 546 SLQF--DGIHVVSGSLDTSIRVW-------DVETGNCIHTLTGHQSL 583
Score = 117 bits (293), Expect = 4e-26
Identities = 84/268 (31%), Positives = 130/268 (48%), Gaps = 24/268 (8%)
Query: 485 IAGGFADSTVRVWS-VTPKKLRSV---------KQASDLSLIDKESDDVLERIMDEKTAS 534
I G D+T++VWS VT K LR++ Q D +I +D L ++ + +T
Sbjct: 394 IVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQMRDNIIISGSTDRTL-KVWNAETGE 452
Query: 535 ELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFS 594
+ LYGH+ V R ++S S D T+R+W ++T CL GH V Q+
Sbjct: 453 CIHTLYGHTSTVRCMHLHEKR--VVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQYD 510
Query: 595 PYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLW 654
G VSG +D + ++W + L GH V +F + +V +GS D ++R+W
Sbjct: 511 --GRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQF--DGIHVVSGSLDTSIRVW 566
Query: 655 DVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKG---HT 711
DV GNC+ TGH+ + N L +G D V +WDI G + L+G H
Sbjct: 567 DVETGNCIHTLTGHQSLTSGMELKDN--ILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQ 624
Query: 712 DTVCSLRFSRDGEILASGSMDNTVRLWD 739
V L+F+++ + + S D TV+LWD
Sbjct: 625 SAVTCLQFNKN--FVITSSDDGTVKLWD 650
Score = 97.8 bits (242), Expect = 3e-20
Identities = 80/290 (27%), Positives = 132/290 (45%), Gaps = 27/290 (9%)
Query: 462 CFYTFLNAYQGLTAVDVTDDSSLIAGGFADSTVRVWSV-TPKKLRSVKQASD----LSLI 516
C T + G+ + + D+ +I G D T++VW+ T + + ++ + + L
Sbjct: 413 CLRTLVGHTGGVWSSQMRDN--IIISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHLH 470
Query: 517 DKE----SDDVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSL 572
+K S D R+ D +T L +L GH V + D ++S + D V++W
Sbjct: 471 EKRVVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQY--DGRRVVSGAYDFMVKVWDP 528
Query: 573 QTFTCLVGYKGHNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNC 632
+T TCL +GH V+ QF G + VSG D R+W + + GH + +
Sbjct: 529 ETETCLHTLQGHTNRVYSLQFD--GIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSG 586
Query: 633 TRFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTG---HKGPIHSLTFSPNGRFLATGAT 689
N + +G+AD TV++WD+ G C++ G H+ + L F+ N F+ T +
Sbjct: 587 MEL--KDNILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKN--FVITSSD 642
Query: 690 DGRVLLWDIGHG-----LMVGELKGHTDTVCSLRFSRDGEILASGSMDNT 734
DG V LWD+ G L+ E G V +R S + A GS + T
Sbjct: 643 DGTVKLWDLKTGEFIRNLVTLESGGSGGVVWRIRASNTKLVCAVGSRNGT 692
Score = 69.3 bits (168), Expect = 1e-11
Identities = 98/467 (20%), Positives = 178/467 (38%), Gaps = 56/467 (11%)
Query: 317 LKRHLQEKQNNQIWNIVQEHLYI--DIFDGMPRSKQQIDAMVGSLAGEAKREANKSKVFF 374
+ R ++E+Q Q+ +EH ++ PR Q D+ G L R + +
Sbjct: 33 MNRVVEEEQQQQLRQQEEEHTARNGEVVGVEPRPGGQNDSQQGQLEENNNRFISVDEDSS 92
Query: 375 GLLKEPEI-EVPLDDEDEEGENEEGKPKKKKPKKDSIGSKSKKQDPNAP----------- 422
G +E E E ++DEE E EE ++ S S + + +
Sbjct: 93 GNQEEQEEDEEHAGEQDEEDEEEEEMDQESDDFDQSDDSSREDEHTHTNSVTNSSSIVDL 152
Query: 423 PQNRIPLPELKDSDKLDKIMNMKETTKRVRLGPDCLPSICFYTFLNAYQGLTAVDVTDDS 482
P +++ P + K+ + ++ + LG + YT +A T
Sbjct: 153 PVHQLSSPFYTKTTKMKRKLDHGSEVRSFSLGKKPC-KVSEYTSTTGLVPCSATPTTFGD 211
Query: 483 SLIAGGFADSTVRVWSVTP--------KKLRSVKQASDLSLIDKESDDV-------LERI 527
A G R+ SV P K +S L +D+ D + ++
Sbjct: 212 LRAANGQGQQRRRITSVQPPTGLQEWLKMFQSWSGPEKLLALDELIDSCEPTQVKHMMQV 271
Query: 528 MDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYK----- 582
++ + + L +Y SF ++ L ++ T R W + L+ +
Sbjct: 272 IEPQFQRDFISLLPKELALYVLSFLEPKDLLQAAQ---TCRYWRILAEDNLLWREKCKEE 328
Query: 583 GHNYPVWDTQ---------FSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADV-NC 632
G + P+ + SP+ ++ R+ W + ++ GH V C
Sbjct: 329 GIDEPLHIKRRKVIKPGFIHSPWKSAYIR--QHRIDTNWRRGELKSPKVLKGHDDHVITC 386
Query: 633 TRFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGR 692
+F N + +GS D T+++W + G C+R GH G + S N + +G+TD
Sbjct: 387 LQFC--GNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQMRDN--IIISGSTDRT 442
Query: 693 VLLWDIGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLWD 739
+ +W+ G + L GHT TV + + + SGS D T+R+WD
Sbjct: 443 LKVWNAETGECIHTLYGHTSTVRCMHLHE--KRVVSGSRDATLRVWD 487
>gi|16117779 F-box and WD repeat domain containing 7 isoform 2 [Homo
sapiens]
Length = 627
Score = 118 bits (295), Expect = 2e-26
Identities = 75/227 (33%), Positives = 116/227 (51%), Gaps = 19/227 (8%)
Query: 537 KILYGHSGPVYGA-SFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSP 595
K+L GH V F +R ++S S+D T+++WS T CL GH VW +Q
Sbjct: 294 KVLKGHDDHVITCLQFCGNR--IVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQMR- 350
Query: 596 YGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWD 655
+SG DR ++W + + + GH + V C H V +GS D T+R+WD
Sbjct: 351 -DNIIISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHLH--EKRVVSGSRDATLRVWD 407
Query: 656 VLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVC 715
+ G C+ + GH + + + +GR + +GA D V +WD + L+GHT+ V
Sbjct: 408 IETGQCLHVLMGHVAAVRCVQY--DGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVY 465
Query: 716 SLRFSRDGEILASGSMDNTVRLWDAIKAFEDLETDD-FTTATGHINL 761
SL+F DG + SGS+D ++R+W D+ET + T TGH +L
Sbjct: 466 SLQF--DGIHVVSGSLDTSIRVW-------DVETGNCIHTLTGHQSL 503
Score = 117 bits (293), Expect = 4e-26
Identities = 84/268 (31%), Positives = 130/268 (48%), Gaps = 24/268 (8%)
Query: 485 IAGGFADSTVRVWS-VTPKKLRSV---------KQASDLSLIDKESDDVLERIMDEKTAS 534
I G D+T++VWS VT K LR++ Q D +I +D L ++ + +T
Sbjct: 314 IVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQMRDNIIISGSTDRTL-KVWNAETGE 372
Query: 535 ELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFS 594
+ LYGH+ V R ++S S D T+R+W ++T CL GH V Q+
Sbjct: 373 CIHTLYGHTSTVRCMHLHEKR--VVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQYD 430
Query: 595 PYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLW 654
G VSG +D + ++W + L GH V +F + +V +GS D ++R+W
Sbjct: 431 --GRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQF--DGIHVVSGSLDTSIRVW 486
Query: 655 DVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKG---HT 711
DV GNC+ TGH+ + N L +G D V +WDI G + L+G H
Sbjct: 487 DVETGNCIHTLTGHQSLTSGMELKDN--ILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQ 544
Query: 712 DTVCSLRFSRDGEILASGSMDNTVRLWD 739
V L+F+++ + + S D TV+LWD
Sbjct: 545 SAVTCLQFNKN--FVITSSDDGTVKLWD 570
Score = 97.8 bits (242), Expect = 3e-20
Identities = 80/290 (27%), Positives = 132/290 (45%), Gaps = 27/290 (9%)
Query: 462 CFYTFLNAYQGLTAVDVTDDSSLIAGGFADSTVRVWSV-TPKKLRSVKQASD----LSLI 516
C T + G+ + + D+ +I G D T++VW+ T + + ++ + + L
Sbjct: 333 CLRTLVGHTGGVWSSQMRDN--IIISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHLH 390
Query: 517 DKE----SDDVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSL 572
+K S D R+ D +T L +L GH V + D ++S + D V++W
Sbjct: 391 EKRVVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQY--DGRRVVSGAYDFMVKVWDP 448
Query: 573 QTFTCLVGYKGHNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNC 632
+T TCL +GH V+ QF G + VSG D R+W + + GH + +
Sbjct: 449 ETETCLHTLQGHTNRVYSLQFD--GIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSG 506
Query: 633 TRFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTG---HKGPIHSLTFSPNGRFLATGAT 689
N + +G+AD TV++WD+ G C++ G H+ + L F+ N F+ T +
Sbjct: 507 MEL--KDNILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKN--FVITSSD 562
Query: 690 DGRVLLWDIGHG-----LMVGELKGHTDTVCSLRFSRDGEILASGSMDNT 734
DG V LWD+ G L+ E G V +R S + A GS + T
Sbjct: 563 DGTVKLWDLKTGEFIRNLVTLESGGSGGVVWRIRASNTKLVCAVGSRNGT 612
Score = 68.6 bits (166), Expect = 2e-11
Identities = 40/134 (29%), Positives = 65/134 (48%), Gaps = 7/134 (5%)
Query: 607 RVARLWATDHYQPLRIFAGHLADV-NCTRFHPNSNYVATGSADRTVRLWDVLNGNCVRIF 665
R+ W + ++ GH V C +F N + +GS D T+++W + G C+R
Sbjct: 280 RIDTNWRRGELKSPKVLKGHDDHVITCLQFC--GNRIVSGSDDNTLKVWSAVTGKCLRTL 337
Query: 666 TGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDGEI 725
GH G + S N + +G+TD + +W+ G + L GHT TV + +
Sbjct: 338 VGHTGGVWSSQMRDN--IIISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHLHE--KR 393
Query: 726 LASGSMDNTVRLWD 739
+ SGS D T+R+WD
Sbjct: 394 VVSGSRDATLRVWD 407
>gi|5729852 guanine nucleotide-binding protein, beta-5 subunit
isoform a [Homo sapiens]
Length = 353
Score = 117 bits (293), Expect = 4e-26
Identities = 72/214 (33%), Positives = 112/214 (52%), Gaps = 4/214 (1%)
Query: 529 DEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPV 588
+E A++ K + H+ + SF+ +L++S DGT LW +++ L + GH V
Sbjct: 139 NENMAAKKKSVAMHTNYLSACSFTNSDMQILTASGDGTCALWDVESGQLLQSFHGHGADV 198
Query: 589 WDTQFSPY--GYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGS 646
+P G FVSGG D+ A +W Q ++ F H +D+N R++P+ + A+GS
Sbjct: 199 LCLDLAPSETGNTFVSGGCDKKAMVWDMRSGQCVQAFETHESDINSVRYYPSGDAFASGS 258
Query: 647 ADRTVRLWDVLNGNCVRIFTGHK--GPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMV 704
D T RL+D+ V I++ S+ FS +GR L G D + +WD+ G V
Sbjct: 259 DDATCRLYDLRADREVAIYSKESIIFGASSVDFSLSGRLLFAGYNDYTINVWDVLKGSRV 318
Query: 705 GELKGHTDTVCSLRFSRDGEILASGSMDNTVRLW 738
L GH + V +LR S DG SGS D+T+R+W
Sbjct: 319 SILFGHENRVSTLRVSPDGTAFCSGSWDHTLRVW 352
Score = 82.0 bits (201), Expect = 2e-15
Identities = 65/250 (26%), Positives = 108/250 (43%), Gaps = 14/250 (5%)
Query: 502 KKLRSVKQASDLSLIDKESDDVLERI--MDEKTASELKILYGHSGPVYGASFSPDRNYLL 559
+ L+ + L D E V ER+ + + + L GH V + D+ ++
Sbjct: 20 ESLKGKLEEERAKLHDVELHQVAERVEALGQFVMKTRRTLKGHGNKVLCMDWCKDKRRIV 79
Query: 560 SSSEDGTVRLWSLQTFTCLVGYKGHNYPVW--DTQFSPYGYYFVSGGHDRVARLWAT--D 615
SSS+DG V +W +FT + W ++P G GG D ++ D
Sbjct: 80 SSSQDGKVIVWD--SFTTNKEHAVTMPCTWVMACAYAPSGCAIACGGLDNKCSVYPLTFD 137
Query: 616 HYQPL----RIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGP 671
+ + + A H ++ F + + T S D T LWDV +G ++ F GH
Sbjct: 138 KNENMAAKKKSVAMHTNYLSACSFTNSDMQILTASGDGTCALWDVESGQLLQSFHGHGAD 197
Query: 672 IHSLTFSPN--GRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDGEILASG 729
+ L +P+ G +G D + ++WD+ G V + H + S+R+ G+ ASG
Sbjct: 198 VLCLDLAPSETGNTFVSGGCDKKAMVWDMRSGQCVQAFETHESDINSVRYYPSGDAFASG 257
Query: 730 SMDNTVRLWD 739
S D T RL+D
Sbjct: 258 SDDATCRLYD 267
Score = 44.7 bits (104), Expect = 3e-04
Identities = 41/197 (20%), Positives = 71/197 (36%), Gaps = 15/197 (7%)
Query: 473 LTAVDVTDDSSLIAGGFADSTVRVWSVTPKKLRSV--KQASDLSLIDKESD--------- 521
L+A T+ I D T +W V +L +D+ +D
Sbjct: 156 LSACSFTNSDMQILTASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAPSETGNTFVSG 215
Query: 522 --DVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLV 579
D + D ++ ++ H + + P + S S+D T RL+ L+ +
Sbjct: 216 GCDKKAMVWDMRSGQCVQAFETHESDINSVRYYPSGDAFASGSDDATCRLYDLRADREVA 275
Query: 580 GYKGHN--YPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHP 637
Y + + FS G +G +D +W + I GH V+ R P
Sbjct: 276 IYSKESIIFGASSVDFSLSGRLLFAGYNDYTINVWDVLKGSRVSILFGHENRVSTLRVSP 335
Query: 638 NSNYVATGSADRTVRLW 654
+ +GS D T+R+W
Sbjct: 336 DGTAFCSGSWDHTLRVW 352
Score = 42.4 bits (98), Expect = 0.002
Identities = 33/123 (26%), Positives = 50/123 (40%), Gaps = 4/123 (3%)
Query: 494 VRVWSVTPKKLRSVKQASDLSLIDKESDDVLERIMDEKTASELKILYGHSGPVYGAS--- 550
V+ + + SV+ SDD R+ D + E+ I Y ++GAS
Sbjct: 232 VQAFETHESDINSVRYYPSGDAFASGSDDATCRLYDLRADREVAI-YSKESIIFGASSVD 290
Query: 551 FSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPYGYYFVSGGHDRVAR 610
FS L + D T+ +W + + + GH V + SP G F SG D R
Sbjct: 291 FSLSGRLLFAGYNDYTINVWDVLKGSRVSILFGHENRVSTLRVSPDGTAFCSGSWDHTLR 350
Query: 611 LWA 613
+WA
Sbjct: 351 VWA 353
>gi|20336270 guanine nucleotide-binding protein, beta-5 subunit
isoform b [Homo sapiens]
Length = 395
Score = 117 bits (293), Expect = 4e-26
Identities = 72/214 (33%), Positives = 112/214 (52%), Gaps = 4/214 (1%)
Query: 529 DEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPV 588
+E A++ K + H+ + SF+ +L++S DGT LW +++ L + GH V
Sbjct: 181 NENMAAKKKSVAMHTNYLSACSFTNSDMQILTASGDGTCALWDVESGQLLQSFHGHGADV 240
Query: 589 WDTQFSPY--GYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGS 646
+P G FVSGG D+ A +W Q ++ F H +D+N R++P+ + A+GS
Sbjct: 241 LCLDLAPSETGNTFVSGGCDKKAMVWDMRSGQCVQAFETHESDINSVRYYPSGDAFASGS 300
Query: 647 ADRTVRLWDVLNGNCVRIFTGHK--GPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMV 704
D T RL+D+ V I++ S+ FS +GR L G D + +WD+ G V
Sbjct: 301 DDATCRLYDLRADREVAIYSKESIIFGASSVDFSLSGRLLFAGYNDYTINVWDVLKGSRV 360
Query: 705 GELKGHTDTVCSLRFSRDGEILASGSMDNTVRLW 738
L GH + V +LR S DG SGS D+T+R+W
Sbjct: 361 SILFGHENRVSTLRVSPDGTAFCSGSWDHTLRVW 394
Score = 82.0 bits (201), Expect = 2e-15
Identities = 65/250 (26%), Positives = 108/250 (43%), Gaps = 14/250 (5%)
Query: 502 KKLRSVKQASDLSLIDKESDDVLERI--MDEKTASELKILYGHSGPVYGASFSPDRNYLL 559
+ L+ + L D E V ER+ + + + L GH V + D+ ++
Sbjct: 62 ESLKGKLEEERAKLHDVELHQVAERVEALGQFVMKTRRTLKGHGNKVLCMDWCKDKRRIV 121
Query: 560 SSSEDGTVRLWSLQTFTCLVGYKGHNYPVW--DTQFSPYGYYFVSGGHDRVARLWAT--D 615
SSS+DG V +W +FT + W ++P G GG D ++ D
Sbjct: 122 SSSQDGKVIVWD--SFTTNKEHAVTMPCTWVMACAYAPSGCAIACGGLDNKCSVYPLTFD 179
Query: 616 HYQPL----RIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGP 671
+ + + A H ++ F + + T S D T LWDV +G ++ F GH
Sbjct: 180 KNENMAAKKKSVAMHTNYLSACSFTNSDMQILTASGDGTCALWDVESGQLLQSFHGHGAD 239
Query: 672 IHSLTFSPN--GRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDGEILASG 729
+ L +P+ G +G D + ++WD+ G V + H + S+R+ G+ ASG
Sbjct: 240 VLCLDLAPSETGNTFVSGGCDKKAMVWDMRSGQCVQAFETHESDINSVRYYPSGDAFASG 299
Query: 730 SMDNTVRLWD 739
S D T RL+D
Sbjct: 300 SDDATCRLYD 309
Score = 44.7 bits (104), Expect = 3e-04
Identities = 41/197 (20%), Positives = 71/197 (36%), Gaps = 15/197 (7%)
Query: 473 LTAVDVTDDSSLIAGGFADSTVRVWSVTPKKLRSV--KQASDLSLIDKESD--------- 521
L+A T+ I D T +W V +L +D+ +D
Sbjct: 198 LSACSFTNSDMQILTASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAPSETGNTFVSG 257
Query: 522 --DVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLV 579
D + D ++ ++ H + + P + S S+D T RL+ L+ +
Sbjct: 258 GCDKKAMVWDMRSGQCVQAFETHESDINSVRYYPSGDAFASGSDDATCRLYDLRADREVA 317
Query: 580 GYKGHN--YPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHP 637
Y + + FS G +G +D +W + I GH V+ R P
Sbjct: 318 IYSKESIIFGASSVDFSLSGRLLFAGYNDYTINVWDVLKGSRVSILFGHENRVSTLRVSP 377
Query: 638 NSNYVATGSADRTVRLW 654
+ +GS D T+R+W
Sbjct: 378 DGTAFCSGSWDHTLRVW 394
Score = 42.4 bits (98), Expect = 0.002
Identities = 33/123 (26%), Positives = 50/123 (40%), Gaps = 4/123 (3%)
Query: 494 VRVWSVTPKKLRSVKQASDLSLIDKESDDVLERIMDEKTASELKILYGHSGPVYGAS--- 550
V+ + + SV+ SDD R+ D + E+ I Y ++GAS
Sbjct: 274 VQAFETHESDINSVRYYPSGDAFASGSDDATCRLYDLRADREVAI-YSKESIIFGASSVD 332
Query: 551 FSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPYGYYFVSGGHDRVAR 610
FS L + D T+ +W + + + GH V + SP G F SG D R
Sbjct: 333 FSLSGRLLFAGYNDYTINVWDVLKGSRVSILFGHENRVSTLRVSPDGTAFCSGSWDHTLR 392
Query: 611 LWA 613
+WA
Sbjct: 393 VWA 395
>gi|19913367 transducin beta-like 1Y [Homo sapiens]
Length = 522
Score = 116 bits (291), Expect = 7e-26
Identities = 80/292 (27%), Positives = 126/292 (43%), Gaps = 36/292 (12%)
Query: 482 SSLIAGGFADSTVRVWSV-------------------------TPKKLRSVKQASDLSLI 516
S L+A G DST R+W++ + K + S+ SD +L+
Sbjct: 191 SDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPSNKDVTSLDWNSDGTLL 250
Query: 517 DKESDDVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFT 576
S D RI E + L H GP++ ++ NY+LS+ D T +W T
Sbjct: 251 AMGSYDGFARIWTE-NGNLASTLGQHKGPIFALKWNKKGNYVLSAGVDKTTIIWDAHTGE 309
Query: 577 CLVGYKGHNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFH 636
+ H+ P D + F S D + P++ F GH +VN ++
Sbjct: 310 AKQQFPFHSAPALDVDWQ-NNMTFASCSTDMCIHVCRLGCDHPVKTFQGHTNEVNAIKWD 368
Query: 637 PNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGR---------FLATG 687
P+ +A+ S D T+++W + CV H I+++ +SP G LA+
Sbjct: 369 PSGMLLASCSDDMTLKIWSMKQDACVHDLQAHSKEIYTIKWSPTGPATSNPNSSIMLASA 428
Query: 688 ATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLWD 739
+ D V LWD+ G+ L H + V S+ FS DG+ LASGS D V +W+
Sbjct: 429 SFDSTVRLWDVEQGVCTHTLMKHQEPVYSVAFSPDGKYLASGSFDKYVHIWN 480
Score = 80.5 bits (197), Expect = 6e-15
Identities = 55/215 (25%), Positives = 96/215 (44%), Gaps = 16/215 (7%)
Query: 538 ILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQ----------TFTCLVGYKGHNYP 587
+L GH V+ +++P + L S S D T R+W+L + GH+ P
Sbjct: 174 VLRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVP 233
Query: 588 ----VWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVA 643
V ++ G G +D AR+W T++ H + +++ NYV
Sbjct: 234 SNKDVTSLDWNSDGTLLAMGSYDGFARIW-TENGNLASTLGQHKGPIFALKWNKKGNYVL 292
Query: 644 TGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLM 703
+ D+T +WD G + F H P + + N F A+ +TD + + +G
Sbjct: 293 SAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNNMTF-ASCSTDMCIHVCRLGCDHP 351
Query: 704 VGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLW 738
V +GHT+ V ++++ G +LAS S D T+++W
Sbjct: 352 VKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIW 386
Score = 60.1 bits (144), Expect = 8e-09
Identities = 37/133 (27%), Positives = 67/133 (50%), Gaps = 15/133 (11%)
Query: 622 IFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDV---LNGNCVRIFT-------GHKGP 671
+ GH ++V ++P S+ +A+GS D T R+W++ NG ++ GH P
Sbjct: 174 VLRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVP 233
Query: 672 ----IHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDGEILA 727
+ SL ++ +G LA G+ DG +W +G + L H + +L++++ G +
Sbjct: 234 SNKDVTSLDWNSDGTLLAMGSYDGFARIWT-ENGNLASTLGQHKGPIFALKWNKKGNYVL 292
Query: 728 SGSMDNTVRLWDA 740
S +D T +WDA
Sbjct: 293 SAGVDKTTIIWDA 305
Score = 39.3 bits (90), Expect = 0.015
Identities = 24/93 (25%), Positives = 39/93 (41%), Gaps = 14/93 (15%)
Query: 660 NCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELK----------G 709
N + GH+ + ++P LA+G+ D +W++ G + G
Sbjct: 170 NKATVLRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGG 229
Query: 710 H----TDTVCSLRFSRDGEILASGSMDNTVRLW 738
H V SL ++ DG +LA GS D R+W
Sbjct: 230 HDVPSNKDVTSLDWNSDGTLLAMGSYDGFARIW 262
>gi|19913365 transducin beta-like 1Y [Homo sapiens]
Length = 522
Score = 116 bits (291), Expect = 7e-26
Identities = 80/292 (27%), Positives = 126/292 (43%), Gaps = 36/292 (12%)
Query: 482 SSLIAGGFADSTVRVWSV-------------------------TPKKLRSVKQASDLSLI 516
S L+A G DST R+W++ + K + S+ SD +L+
Sbjct: 191 SDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPSNKDVTSLDWNSDGTLL 250
Query: 517 DKESDDVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFT 576
S D RI E + L H GP++ ++ NY+LS+ D T +W T
Sbjct: 251 AMGSYDGFARIWTE-NGNLASTLGQHKGPIFALKWNKKGNYVLSAGVDKTTIIWDAHTGE 309
Query: 577 CLVGYKGHNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFH 636
+ H+ P D + F S D + P++ F GH +VN ++
Sbjct: 310 AKQQFPFHSAPALDVDWQ-NNMTFASCSTDMCIHVCRLGCDHPVKTFQGHTNEVNAIKWD 368
Query: 637 PNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGR---------FLATG 687
P+ +A+ S D T+++W + CV H I+++ +SP G LA+
Sbjct: 369 PSGMLLASCSDDMTLKIWSMKQDACVHDLQAHSKEIYTIKWSPTGPATSNPNSSIMLASA 428
Query: 688 ATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLWD 739
+ D V LWD+ G+ L H + V S+ FS DG+ LASGS D V +W+
Sbjct: 429 SFDSTVRLWDVEQGVCTHTLMKHQEPVYSVAFSPDGKYLASGSFDKYVHIWN 480
Score = 80.5 bits (197), Expect = 6e-15
Identities = 55/215 (25%), Positives = 96/215 (44%), Gaps = 16/215 (7%)
Query: 538 ILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQ----------TFTCLVGYKGHNYP 587
+L GH V+ +++P + L S S D T R+W+L + GH+ P
Sbjct: 174 VLRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVP 233
Query: 588 ----VWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVA 643
V ++ G G +D AR+W T++ H + +++ NYV
Sbjct: 234 SNKDVTSLDWNSDGTLLAMGSYDGFARIW-TENGNLASTLGQHKGPIFALKWNKKGNYVL 292
Query: 644 TGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLM 703
+ D+T +WD G + F H P + + N F A+ +TD + + +G
Sbjct: 293 SAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNNMTF-ASCSTDMCIHVCRLGCDHP 351
Query: 704 VGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLW 738
V +GHT+ V ++++ G +LAS S D T+++W
Sbjct: 352 VKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIW 386
Score = 60.1 bits (144), Expect = 8e-09
Identities = 37/133 (27%), Positives = 67/133 (50%), Gaps = 15/133 (11%)
Query: 622 IFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDV---LNGNCVRIFT-------GHKGP 671
+ GH ++V ++P S+ +A+GS D T R+W++ NG ++ GH P
Sbjct: 174 VLRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVP 233
Query: 672 ----IHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDGEILA 727
+ SL ++ +G LA G+ DG +W +G + L H + +L++++ G +
Sbjct: 234 SNKDVTSLDWNSDGTLLAMGSYDGFARIWT-ENGNLASTLGQHKGPIFALKWNKKGNYVL 292
Query: 728 SGSMDNTVRLWDA 740
S +D T +WDA
Sbjct: 293 SAGVDKTTIIWDA 305
Score = 39.3 bits (90), Expect = 0.015
Identities = 24/93 (25%), Positives = 39/93 (41%), Gaps = 14/93 (15%)
Query: 660 NCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELK----------G 709
N + GH+ + ++P LA+G+ D +W++ G + G
Sbjct: 170 NKATVLRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGG 229
Query: 710 H----TDTVCSLRFSRDGEILASGSMDNTVRLW 738
H V SL ++ DG +LA GS D R+W
Sbjct: 230 HDVPSNKDVTSLDWNSDGTLLAMGSYDGFARIW 262
>gi|15150805 transducin beta-like 1Y [Homo sapiens]
Length = 522
Score = 116 bits (291), Expect = 7e-26
Identities = 80/292 (27%), Positives = 126/292 (43%), Gaps = 36/292 (12%)
Query: 482 SSLIAGGFADSTVRVWSV-------------------------TPKKLRSVKQASDLSLI 516
S L+A G DST R+W++ + K + S+ SD +L+
Sbjct: 191 SDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPSNKDVTSLDWNSDGTLL 250
Query: 517 DKESDDVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFT 576
S D RI E + L H GP++ ++ NY+LS+ D T +W T
Sbjct: 251 AMGSYDGFARIWTE-NGNLASTLGQHKGPIFALKWNKKGNYVLSAGVDKTTIIWDAHTGE 309
Query: 577 CLVGYKGHNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFH 636
+ H+ P D + F S D + P++ F GH +VN ++
Sbjct: 310 AKQQFPFHSAPALDVDWQ-NNMTFASCSTDMCIHVCRLGCDHPVKTFQGHTNEVNAIKWD 368
Query: 637 PNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGR---------FLATG 687
P+ +A+ S D T+++W + CV H I+++ +SP G LA+
Sbjct: 369 PSGMLLASCSDDMTLKIWSMKQDACVHDLQAHSKEIYTIKWSPTGPATSNPNSSIMLASA 428
Query: 688 ATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLWD 739
+ D V LWD+ G+ L H + V S+ FS DG+ LASGS D V +W+
Sbjct: 429 SFDSTVRLWDVEQGVCTHTLMKHQEPVYSVAFSPDGKYLASGSFDKYVHIWN 480
Score = 80.5 bits (197), Expect = 6e-15
Identities = 55/215 (25%), Positives = 96/215 (44%), Gaps = 16/215 (7%)
Query: 538 ILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQ----------TFTCLVGYKGHNYP 587
+L GH V+ +++P + L S S D T R+W+L + GH+ P
Sbjct: 174 VLRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVP 233
Query: 588 ----VWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVA 643
V ++ G G +D AR+W T++ H + +++ NYV
Sbjct: 234 SNKDVTSLDWNSDGTLLAMGSYDGFARIW-TENGNLASTLGQHKGPIFALKWNKKGNYVL 292
Query: 644 TGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLM 703
+ D+T +WD G + F H P + + N F A+ +TD + + +G
Sbjct: 293 SAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNNMTF-ASCSTDMCIHVCRLGCDHP 351
Query: 704 VGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLW 738
V +GHT+ V ++++ G +LAS S D T+++W
Sbjct: 352 VKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIW 386
Score = 60.1 bits (144), Expect = 8e-09
Identities = 37/133 (27%), Positives = 67/133 (50%), Gaps = 15/133 (11%)
Query: 622 IFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDV---LNGNCVRIFT-------GHKGP 671
+ GH ++V ++P S+ +A+GS D T R+W++ NG ++ GH P
Sbjct: 174 VLRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVP 233
Query: 672 ----IHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDGEILA 727
+ SL ++ +G LA G+ DG +W +G + L H + +L++++ G +
Sbjct: 234 SNKDVTSLDWNSDGTLLAMGSYDGFARIWT-ENGNLASTLGQHKGPIFALKWNKKGNYVL 292
Query: 728 SGSMDNTVRLWDA 740
S +D T +WDA
Sbjct: 293 SAGVDKTTIIWDA 305
Score = 39.3 bits (90), Expect = 0.015
Identities = 24/93 (25%), Positives = 39/93 (41%), Gaps = 14/93 (15%)
Query: 660 NCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELK----------G 709
N + GH+ + ++P LA+G+ D +W++ G + G
Sbjct: 170 NKATVLRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGG 229
Query: 710 H----TDTVCSLRFSRDGEILASGSMDNTVRLW 738
H V SL ++ DG +LA GS D R+W
Sbjct: 230 HDVPSNKDVTSLDWNSDGTLLAMGSYDGFARIW 262
>gi|70909324 sperm associated antigen 16 isoform 1 [Homo sapiens]
Length = 631
Score = 115 bits (288), Expect = 2e-25
Identities = 72/259 (27%), Positives = 112/259 (43%), Gaps = 41/259 (15%)
Query: 521 DDVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVG 580
+D L +++ + L +GH+ + F P + L +SS D TV+LW L C++
Sbjct: 372 EDRLWKVLGLPKCNVLLTGFGHTDWLSDCCFHPSGDKLATSSGDTTVKLWDLCKGDCILT 431
Query: 581 YKGHNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSN 640
++GH+ VW + G + S D+ +++W + + GH VN F P SN
Sbjct: 432 FEGHSRAVWSCTWHSCGNFVASSSLDKTSKIWDVNSERCRCTLYGHTDSVNSIEFFPFSN 491
Query: 641 YVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDI-- 698
+ T SAD+T+ +WD G C + GH I+ F P G +A+ G LWD
Sbjct: 492 TLLTSSADKTLSIWDARTGICEQSLYGHMHSINDAIFDPRGHMIASCDACGVTKLWDFRK 551
Query: 699 ------------------------------GHGLM---------VGELKGHTDTVCSLRF 719
G+G++ + +L GH + ++ F
Sbjct: 552 LLPIVSIDIGPSPGNEVNFDSSGRVLAQASGNGVIHLLDLKSGEIHKLMGHENEAHTVVF 611
Query: 720 SRDGEILASGSMDNTVRLW 738
S DGEIL SG D TVR W
Sbjct: 612 SHDGEILFSGGSDGTVRTW 630
Score = 95.9 bits (237), Expect = 1e-19
Identities = 52/160 (32%), Positives = 79/160 (49%)
Query: 581 YKGHNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSN 640
++ H PV P+ VS G DR+ ++ L GH ++ FHP+ +
Sbjct: 348 FRLHELPVSCVSMQPHKDILVSCGEDRLWKVLGLPKCNVLLTGFGHTDWLSDCCFHPSGD 407
Query: 641 YVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGH 700
+AT S D TV+LWD+ G+C+ F GH + S T+ G F+A+ + D +WD+
Sbjct: 408 KLATSSGDTTVKLWDLCKGDCILTFEGHSRAVWSCTWHSCGNFVASSSLDKTSKIWDVNS 467
Query: 701 GLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLWDA 740
L GHTD+V S+ F L + S D T+ +WDA
Sbjct: 468 ERCRCTLYGHTDSVNSIEFFPFSNTLLTSSADKTLSIWDA 507
Score = 93.6 bits (231), Expect = 7e-19
Identities = 63/242 (26%), Positives = 98/242 (40%), Gaps = 4/242 (1%)
Query: 542 HSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPYGYYFV 601
H PV S P ++ L+S ED ++ L L+ GH + D F P G
Sbjct: 351 HELPVSCVSMQPHKDILVSCGEDRLWKVLGLPKCNVLLTGFGHTDWLSDCCFHPSGDKLA 410
Query: 602 SGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLNGNC 661
+ D +LW + F GH V +H N+VA+ S D+T ++WDV + C
Sbjct: 411 TSSGDTTVKLWDLCKGDCILTFEGHSRAVWSCTWHSCGNFVASSSLDKTSKIWDVNSERC 470
Query: 662 VRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSR 721
GH ++S+ F P L T + D + +WD G+ L GH ++ F
Sbjct: 471 RCTLYGHTDSVNSIEFFPFSNTLLTSSADKTLSIWDARTGICEQSLYGHMHSINDAIFDP 530
Query: 722 DGEILASGSMDNTVRLWDAIKAFEDLETDDFTTATGHINLPENSQELLLGTYMTKSTPVV 781
G ++AS +LWD K + D + +N + + L V+
Sbjct: 531 RGHMIASCDACGVTKLWDFRKLLPIVSIDIGPSPGNEVNFDSSGRVLA----QASGNGVI 586
Query: 782 HL 783
HL
Sbjct: 587 HL 588
Score = 82.0 bits (201), Expect = 2e-15
Identities = 93/390 (23%), Positives = 147/390 (37%), Gaps = 54/390 (13%)
Query: 353 DAMVGSLAG--EAKREANKSKVFFGLLKEPEIEVPLDDEDE---EGENEEGKPKKKKPKK 407
D +VG ++G E ++ + + G P+I+V E E EG ++G + ++ K
Sbjct: 249 DKVVGQISGLQETLKKLQRGHSYHG----PQIKVDHSREKENAPEGPTQKGLREAREQNK 304
Query: 408 DSIGSKSKKQDPNAPPQNRIPLPELKDSD----------KLDKIMNMKETTKR------- 450
K +D P + P P L S KL I + E
Sbjct: 305 CKTKMKGNTKDSEFPIDMQ-PNPNLNVSKESLSPAKFDYKLKNIFRLHELPVSCVSMQPH 363
Query: 451 ----VRLGPDCLPSICFYTFLNAYQGLTAVDVTD---------DSSLIAGGFADSTVRVW 497
V G D L + N LT TD +A D+TV++W
Sbjct: 364 KDILVSCGEDRLWKVLGLPKCNVL--LTGFGHTDWLSDCCFHPSGDKLATSSGDTTVKLW 421
Query: 498 SVTP-----------KKLRSVKQASDLSLIDKESDDVLERIMDEKTASELKILYGHSGPV 546
+ + + S S + + S D +I D + LYGH+ V
Sbjct: 422 DLCKGDCILTFEGHSRAVWSCTWHSCGNFVASSSLDKTSKIWDVNSERCRCTLYGHTDSV 481
Query: 547 YGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPYGYYFVSGGHD 606
F P N LL+SS D T+ +W +T C GH + + D F P G+ S
Sbjct: 482 NSIEFFPFSNTLLTSSADKTLSIWDARTGICEQSLYGHMHSINDAIFDPRGHMIASCDAC 541
Query: 607 RVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLNGNCVRIFT 666
V +LW P+ + N F + +A S + + L D+ +G ++
Sbjct: 542 GVTKLWDFRKLLPIVSIDIGPSPGNEVNFDSSGRVLAQASGNGVIHLLDLKSGEIHKLM- 600
Query: 667 GHKGPIHSLTFSPNGRFLATGATDGRVLLW 696
GH+ H++ FS +G L +G +DG V W
Sbjct: 601 GHENEAHTVVFSHDGEILFSGGSDGTVRTW 630
Score = 63.5 bits (153), Expect = 7e-10
Identities = 41/126 (32%), Positives = 60/126 (47%), Gaps = 6/126 (4%)
Query: 617 YQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLN-GNCVRIFTG--HKGPIH 673
Y+ IF H V+C P+ + + + DR LW VL C + TG H +
Sbjct: 342 YKLKNIFRLHELPVSCVSMQPHKDILVSCGEDR---LWKVLGLPKCNVLLTGFGHTDWLS 398
Query: 674 SLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDN 733
F P+G LAT + D V LWD+ G + +GH+ V S + G +AS S+D
Sbjct: 399 DCCFHPSGDKLATSSGDTTVKLWDLCKGDCILTFEGHSRAVWSCTWHSCGNFVASSSLDK 458
Query: 734 TVRLWD 739
T ++WD
Sbjct: 459 TSKIWD 464
Score = 34.7 bits (78), Expect = 0.36
Identities = 22/73 (30%), Positives = 33/73 (45%), Gaps = 1/73 (1%)
Query: 499 VTPKKLRSVKQASDLSLIDKESDDVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYL 558
+ P V S ++ + S + + ++D K+ E+ L GH + FS D L
Sbjct: 560 IGPSPGNEVNFDSSGRVLAQASGNGVIHLLDLKSG-EIHKLMGHENEAHTVVFSHDGEIL 618
Query: 559 LSSSEDGTVRLWS 571
S DGTVR WS
Sbjct: 619 FSGGSDGTVRTWS 631
>gi|4557741 platelet-activating factor acetylhydrolase, isoform Ib,
alpha subunit [Homo sapiens]
Length = 410
Score = 114 bits (285), Expect = 4e-25
Identities = 66/246 (26%), Positives = 111/246 (45%), Gaps = 20/246 (8%)
Query: 514 SLIDKESDDVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQ 573
S++ S+D ++ D +T + L GH+ V SF L S S D T++LW Q
Sbjct: 121 SVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQ 180
Query: 574 TFTCLVGYKGHNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCT 633
F C+ GH++ V P G + VS D+ ++W ++ F GH V
Sbjct: 181 GFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMV 240
Query: 634 RFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPN------------- 680
R + + +A+ S D+TVR+W V C H+ + ++++P
Sbjct: 241 RPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSISEATGSE 300
Query: 681 -------GRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDN 733
G FL +G+ D + +WD+ G+ + L GH + V + F G+ + S + D
Sbjct: 301 TKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDK 360
Query: 734 TVRLWD 739
T+R+WD
Sbjct: 361 TLRVWD 366
Score = 110 bits (275), Expect = 5e-24
Identities = 61/221 (27%), Positives = 103/221 (46%), Gaps = 20/221 (9%)
Query: 539 LYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPYGY 598
L GH PV F P + ++S+SED T+++W +T KGH V D F G
Sbjct: 104 LSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGK 163
Query: 599 YFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLN 658
S D +LW ++ +R GH +V+ PN +++ + S D+T+++W+V
Sbjct: 164 LLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQT 223
Query: 659 GNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLR 718
G CV+ FTGH+ + + + +G +A+ + D V +W + EL+ H V +
Sbjct: 224 GYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECIS 283
Query: 719 FS--------------------RDGEILASGSMDNTVRLWD 739
++ + G L SGS D T+++WD
Sbjct: 284 WAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWD 324
Score = 110 bits (275), Expect = 5e-24
Identities = 69/288 (23%), Positives = 130/288 (45%), Gaps = 31/288 (10%)
Query: 483 SLIAGGFADSTVRVWSV-TPKKLRSVKQASDL----------SLIDKESDDVLERIMDEK 531
S++ D+T++VW T R++K +D L+ S D+ ++ D +
Sbjct: 121 SVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQ 180
Query: 532 TASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDT 591
++ ++GH V + P+ ++++S+S D T+++W +QT C+ + GH V
Sbjct: 181 GFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMV 240
Query: 592 QFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNY---------- 641
+ + G S +D+ R+W + H V C + P S+Y
Sbjct: 241 RPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSISEATGSE 300
Query: 642 ----------VATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDG 691
+ +GS D+T+++WDV G C+ GH + + F G+F+ + A D
Sbjct: 301 TKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDK 360
Query: 692 RVLLWDIGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLWD 739
+ +WD + + L H V SL F + + +GS+D TV++W+
Sbjct: 361 TLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWE 408
Score = 82.4 bits (202), Expect = 2e-15
Identities = 60/204 (29%), Positives = 90/204 (44%), Gaps = 31/204 (15%)
Query: 462 CFYTFLNAYQGLTAVDVTDDSSLIAGGFADSTVRVWSVTPKKLRSVKQASDLSLIDKESD 521
C TF + + V D +LIA D TVRVW V K+ ++ +E +
Sbjct: 226 CVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAEL---------REHE 276
Query: 522 DVLERI----------MDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWS 571
V+E I + E T SE K G GP +LLS S D T+++W
Sbjct: 277 HVVECISWAPESSYSSISEATGSETK-KSGKPGP-----------FLLSGSRDKTIKMWD 324
Query: 572 LQTFTCLVGYKGHNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVN 631
+ T CL+ GH+ V F G + +S D+ R+W + + ++ H V
Sbjct: 325 VSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNAHEHFVT 384
Query: 632 CTRFHPNSNYVATGSADRTVRLWD 655
FH + YV TGS D+TV++W+
Sbjct: 385 SLDFHKTAPYVVTGSVDQTVKVWE 408
>gi|11321585 guanine nucleotide-binding protein, beta-1 subunit
[Homo sapiens]
Length = 340
Score = 114 bits (285), Expect = 4e-25
Identities = 70/242 (28%), Positives = 115/242 (47%), Gaps = 9/242 (3%)
Query: 537 KILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPY 596
+ L GH +Y + D L+S+S+DG + +W T + + V ++P
Sbjct: 49 RTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPS 108
Query: 597 GYYFVSGGHDRVARLW----ATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVR 652
G Y GG D + ++ + + R AGH ++C RF + N + T S D T
Sbjct: 109 GNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFL-DDNQIVTSSGDTTCA 167
Query: 653 LWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHTD 712
LWD+ G FTGH G + SL+ +P+ R +GA D LWD+ G+ GH
Sbjct: 168 LWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHES 227
Query: 713 TVCSLRFSRDGEILASGSMDNTVRLWDAIKAFEDLET---DDFTTATGHINLPENSQELL 769
+ ++ F +G A+GS D T RL+D ++A ++L T D+ ++ ++ + LL
Sbjct: 228 DINAICFFPNGNAFATGSDDATCRLFD-LRADQELMTYSHDNIICGITSVSFSKSGRLLL 286
Query: 770 LG 771
G
Sbjct: 287 AG 288
Score = 107 bits (266), Expect = 6e-23
Identities = 68/203 (33%), Positives = 99/203 (48%), Gaps = 3/203 (1%)
Query: 539 LYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPYGY 598
L GH+G + F D N +++SS D T LW ++T + GH V +P
Sbjct: 139 LAGHTGYLSCCRFLDD-NQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTR 197
Query: 599 YFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLN 658
FVSG D A+LW + F GH +D+N F PN N ATGS D T RL+D+
Sbjct: 198 LFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRA 257
Query: 659 GNCVRIFTGHK--GPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCS 716
+ ++ I S++FS +GR L G D +WD G L GH + V
Sbjct: 258 DQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSC 317
Query: 717 LRFSRDGEILASGSMDNTVRLWD 739
L + DG +A+GS D+ +++W+
Sbjct: 318 LGVTDDGMAVATGSWDSFLKIWN 340
Score = 100 bits (250), Expect = 4e-21
Identities = 71/250 (28%), Positives = 113/250 (45%), Gaps = 13/250 (5%)
Query: 503 KLRSVKQASDLSLIDKESDDVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSS 562
K+ ++ +D L+ S D I D T +++ + S V +++P NY+
Sbjct: 57 KIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGG 116
Query: 563 EDGTVRLWSLQTFTCLVGYK----GHNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQ 618
D +++L+T V GH + +F S G D LW + Q
Sbjct: 117 LDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSG-DTTCALWDIETGQ 175
Query: 619 PLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFS 678
F GH DV P++ +G+ D + +LWDV G C + FTGH+ I+++ F
Sbjct: 176 QTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFF 235
Query: 679 PNGRFLATGATDGRVLLWDI--GHGLMVGELKGHTDTVC---SLRFSRDGEILASGSMDN 733
PNG ATG+ D L+D+ LM H + +C S+ FS+ G +L +G D
Sbjct: 236 PNGNAFATGSDDATCRLFDLRADQELMT---YSHDNIICGITSVSFSKSGRLLLAGYDDF 292
Query: 734 TVRLWDAIKA 743
+WDA+KA
Sbjct: 293 NCNVWDALKA 302
Score = 74.7 bits (182), Expect = 3e-13
Identities = 45/188 (23%), Positives = 78/188 (41%), Gaps = 2/188 (1%)
Query: 512 DLSLIDKESDDVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWS 571
D + I S D + D +T + GH+G V S +PD +S + D + +LW
Sbjct: 153 DDNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWD 212
Query: 572 LQTFTCLVGYKGHNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFA--GHLAD 629
++ C + GH + F P G F +G D RL+ Q L ++ +
Sbjct: 213 VREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICG 272
Query: 630 VNCTRFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGAT 689
+ F + + G D +WD L + + GH + L + +G +ATG+
Sbjct: 273 ITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSW 332
Query: 690 DGRVLLWD 697
D + +W+
Sbjct: 333 DSFLKIWN 340
Score = 55.8 bits (133), Expect = 2e-07
Identities = 52/234 (22%), Positives = 90/234 (38%), Gaps = 25/234 (10%)
Query: 436 DKLDKIMNMKETTKRVRLGPDCLPSICFYTFLNAYQG-LTAVDVTDDSSLIAGGFADSTV 494
D + I N+K VR+ + L + G L+ DD+ ++ D+T
Sbjct: 118 DNICSIYNLKTREGNVRVSRE----------LAGHTGYLSCCRFLDDNQIVTSS-GDTTC 166
Query: 495 RVWSVTPKK-----------LRSVKQASDLSLIDKESDDVLERIMDEKTASELKILYGHS 543
+W + + + S+ A D L + D ++ D + + GH
Sbjct: 167 ALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHE 226
Query: 544 GPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNY--PVWDTQFSPYGYYFV 601
+ F P+ N + S+D T RL+ L+ L+ Y N + FS G +
Sbjct: 227 SDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLL 286
Query: 602 SGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWD 655
+G D +W + AGH V+C + VATGS D +++W+
Sbjct: 287 AGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
>gi|213021190 transducin beta-like 1X isoform b [Homo sapiens]
Length = 526
Score = 112 bits (281), Expect = 1e-24
Identities = 78/292 (26%), Positives = 127/292 (43%), Gaps = 36/292 (12%)
Query: 482 SSLIAGGFADSTVRVWSV-------------------------TPKKLRSVKQASDLSLI 516
S L+A G DST R+W++ + K + S+ ++ +L+
Sbjct: 193 SDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPSNKDVTSLDWNTNGTLL 252
Query: 517 DKESDDVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFT 576
S D RI E + L H GP++ ++ NY+LS+ D T +W T
Sbjct: 253 ATGSYDGFARIWTE-DGNLASTLGQHKGPIFALKWNRKGNYILSAGVDKTTIIWDAHTGE 311
Query: 577 CLVGYKGHNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFH 636
+ H+ P D + F S D + +P++ F GH +VN ++
Sbjct: 312 AKQQFPFHSAPALDVDWQ-NNTTFASCSTDMCIHVCRLGCDRPVKTFQGHTNEVNAIKWD 370
Query: 637 PNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGR---------FLATG 687
P+ +A+ S D T+++W + C+ H I+++ +SP G LA+
Sbjct: 371 PSGMLLASCSDDMTLKIWSMKQEVCIHDLQAHNKEIYTIKWSPTGPATSNPNSNIMLASA 430
Query: 688 ATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLWD 739
+ D V LWDI G+ L H + V S+ FS DG+ LASGS D V +W+
Sbjct: 431 SFDSTVRLWDIERGVCTHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWN 482
Score = 82.8 bits (203), Expect = 1e-15
Identities = 56/223 (25%), Positives = 100/223 (44%), Gaps = 16/223 (7%)
Query: 530 EKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQ----------TFTCLV 579
E +S+ +L GH V+ +++P + L S S D T R+W+L +
Sbjct: 168 EIPSSKATVLRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCI 227
Query: 580 GYKGHNYP----VWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRF 635
GH+ P V ++ G +G +D AR+W T+ H + ++
Sbjct: 228 REGGHDVPSNKDVTSLDWNTNGTLLATGSYDGFARIW-TEDGNLASTLGQHKGPIFALKW 286
Query: 636 HPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLL 695
+ NY+ + D+T +WD G + F H P + + N F A+ +TD + +
Sbjct: 287 NRKGNYILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNNTTF-ASCSTDMCIHV 345
Query: 696 WDIGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLW 738
+G V +GHT+ V ++++ G +LAS S D T+++W
Sbjct: 346 CRLGCDRPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIW 388
Score = 30.4 bits (67), Expect = 6.8
Identities = 13/33 (39%), Positives = 21/33 (63%)
Query: 707 LKGHTDTVCSLRFSRDGEILASGSMDNTVRLWD 739
L+GH V ++ ++LASGS D+T R+W+
Sbjct: 177 LRGHESEVFICAWNPVSDLLASGSGDSTARIWN 209
>gi|213021188 transducin beta-like 1X isoform b [Homo sapiens]
Length = 526
Score = 112 bits (281), Expect = 1e-24
Identities = 78/292 (26%), Positives = 127/292 (43%), Gaps = 36/292 (12%)
Query: 482 SSLIAGGFADSTVRVWSV-------------------------TPKKLRSVKQASDLSLI 516
S L+A G DST R+W++ + K + S+ ++ +L+
Sbjct: 193 SDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPSNKDVTSLDWNTNGTLL 252
Query: 517 DKESDDVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFT 576
S D RI E + L H GP++ ++ NY+LS+ D T +W T
Sbjct: 253 ATGSYDGFARIWTE-DGNLASTLGQHKGPIFALKWNRKGNYILSAGVDKTTIIWDAHTGE 311
Query: 577 CLVGYKGHNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFH 636
+ H+ P D + F S D + +P++ F GH +VN ++
Sbjct: 312 AKQQFPFHSAPALDVDWQ-NNTTFASCSTDMCIHVCRLGCDRPVKTFQGHTNEVNAIKWD 370
Query: 637 PNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGR---------FLATG 687
P+ +A+ S D T+++W + C+ H I+++ +SP G LA+
Sbjct: 371 PSGMLLASCSDDMTLKIWSMKQEVCIHDLQAHNKEIYTIKWSPTGPATSNPNSNIMLASA 430
Query: 688 ATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLWD 739
+ D V LWDI G+ L H + V S+ FS DG+ LASGS D V +W+
Sbjct: 431 SFDSTVRLWDIERGVCTHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWN 482
Score = 82.8 bits (203), Expect = 1e-15
Identities = 56/223 (25%), Positives = 100/223 (44%), Gaps = 16/223 (7%)
Query: 530 EKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQ----------TFTCLV 579
E +S+ +L GH V+ +++P + L S S D T R+W+L +
Sbjct: 168 EIPSSKATVLRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCI 227
Query: 580 GYKGHNYP----VWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRF 635
GH+ P V ++ G +G +D AR+W T+ H + ++
Sbjct: 228 REGGHDVPSNKDVTSLDWNTNGTLLATGSYDGFARIW-TEDGNLASTLGQHKGPIFALKW 286
Query: 636 HPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLL 695
+ NY+ + D+T +WD G + F H P + + N F A+ +TD + +
Sbjct: 287 NRKGNYILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNNTTF-ASCSTDMCIHV 345
Query: 696 WDIGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLW 738
+G V +GHT+ V ++++ G +LAS S D T+++W
Sbjct: 346 CRLGCDRPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIW 388
Score = 30.4 bits (67), Expect = 6.8
Identities = 13/33 (39%), Positives = 21/33 (63%)
Query: 707 LKGHTDTVCSLRFSRDGEILASGSMDNTVRLWD 739
L+GH V ++ ++LASGS D+T R+W+
Sbjct: 177 LRGHESEVFICAWNPVSDLLASGSGDSTARIWN 209
>gi|213021186 transducin beta-like 1X isoform a [Homo sapiens]
Length = 577
Score = 112 bits (281), Expect = 1e-24
Identities = 78/292 (26%), Positives = 127/292 (43%), Gaps = 36/292 (12%)
Query: 482 SSLIAGGFADSTVRVWSV-------------------------TPKKLRSVKQASDLSLI 516
S L+A G DST R+W++ + K + S+ ++ +L+
Sbjct: 244 SDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPSNKDVTSLDWNTNGTLL 303
Query: 517 DKESDDVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFT 576
S D RI E + L H GP++ ++ NY+LS+ D T +W T
Sbjct: 304 ATGSYDGFARIWTE-DGNLASTLGQHKGPIFALKWNRKGNYILSAGVDKTTIIWDAHTGE 362
Query: 577 CLVGYKGHNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFH 636
+ H+ P D + F S D + +P++ F GH +VN ++
Sbjct: 363 AKQQFPFHSAPALDVDWQ-NNTTFASCSTDMCIHVCRLGCDRPVKTFQGHTNEVNAIKWD 421
Query: 637 PNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGR---------FLATG 687
P+ +A+ S D T+++W + C+ H I+++ +SP G LA+
Sbjct: 422 PSGMLLASCSDDMTLKIWSMKQEVCIHDLQAHNKEIYTIKWSPTGPATSNPNSNIMLASA 481
Query: 688 ATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLWD 739
+ D V LWDI G+ L H + V S+ FS DG+ LASGS D V +W+
Sbjct: 482 SFDSTVRLWDIERGVCTHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWN 533
Score = 82.8 bits (203), Expect = 1e-15
Identities = 56/223 (25%), Positives = 100/223 (44%), Gaps = 16/223 (7%)
Query: 530 EKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQ----------TFTCLV 579
E +S+ +L GH V+ +++P + L S S D T R+W+L +
Sbjct: 219 EIPSSKATVLRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCI 278
Query: 580 GYKGHNYP----VWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRF 635
GH+ P V ++ G +G +D AR+W T+ H + ++
Sbjct: 279 REGGHDVPSNKDVTSLDWNTNGTLLATGSYDGFARIW-TEDGNLASTLGQHKGPIFALKW 337
Query: 636 HPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLL 695
+ NY+ + D+T +WD G + F H P + + N F A+ +TD + +
Sbjct: 338 NRKGNYILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNNTTF-ASCSTDMCIHV 396
Query: 696 WDIGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLW 738
+G V +GHT+ V ++++ G +LAS S D T+++W
Sbjct: 397 CRLGCDRPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIW 439
Score = 30.4 bits (67), Expect = 6.8
Identities = 13/33 (39%), Positives = 21/33 (63%)
Query: 707 LKGHTDTVCSLRFSRDGEILASGSMDNTVRLWD 739
L+GH V ++ ++LASGS D+T R+W+
Sbjct: 228 LRGHESEVFICAWNPVSDLLASGSGDSTARIWN 260
>gi|5032159 transducin beta-like 1X isoform a [Homo sapiens]
Length = 577
Score = 112 bits (281), Expect = 1e-24
Identities = 78/292 (26%), Positives = 127/292 (43%), Gaps = 36/292 (12%)
Query: 482 SSLIAGGFADSTVRVWSV-------------------------TPKKLRSVKQASDLSLI 516
S L+A G DST R+W++ + K + S+ ++ +L+
Sbjct: 244 SDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPSNKDVTSLDWNTNGTLL 303
Query: 517 DKESDDVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFT 576
S D RI E + L H GP++ ++ NY+LS+ D T +W T
Sbjct: 304 ATGSYDGFARIWTE-DGNLASTLGQHKGPIFALKWNRKGNYILSAGVDKTTIIWDAHTGE 362
Query: 577 CLVGYKGHNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFH 636
+ H+ P D + F S D + +P++ F GH +VN ++
Sbjct: 363 AKQQFPFHSAPALDVDWQ-NNTTFASCSTDMCIHVCRLGCDRPVKTFQGHTNEVNAIKWD 421
Query: 637 PNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGR---------FLATG 687
P+ +A+ S D T+++W + C+ H I+++ +SP G LA+
Sbjct: 422 PSGMLLASCSDDMTLKIWSMKQEVCIHDLQAHNKEIYTIKWSPTGPATSNPNSNIMLASA 481
Query: 688 ATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLWD 739
+ D V LWDI G+ L H + V S+ FS DG+ LASGS D V +W+
Sbjct: 482 SFDSTVRLWDIERGVCTHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWN 533
Score = 82.8 bits (203), Expect = 1e-15
Identities = 56/223 (25%), Positives = 100/223 (44%), Gaps = 16/223 (7%)
Query: 530 EKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQ----------TFTCLV 579
E +S+ +L GH V+ +++P + L S S D T R+W+L +
Sbjct: 219 EIPSSKATVLRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCI 278
Query: 580 GYKGHNYP----VWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRF 635
GH+ P V ++ G +G +D AR+W T+ H + ++
Sbjct: 279 REGGHDVPSNKDVTSLDWNTNGTLLATGSYDGFARIW-TEDGNLASTLGQHKGPIFALKW 337
Query: 636 HPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLL 695
+ NY+ + D+T +WD G + F H P + + N F A+ +TD + +
Sbjct: 338 NRKGNYILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNNTTF-ASCSTDMCIHV 396
Query: 696 WDIGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLW 738
+G V +GHT+ V ++++ G +LAS S D T+++W
Sbjct: 397 CRLGCDRPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIW 439
Score = 30.4 bits (67), Expect = 6.8
Identities = 13/33 (39%), Positives = 21/33 (63%)
Query: 707 LKGHTDTVCSLRFSRDGEILASGSMDNTVRLWD 739
L+GH V ++ ++LASGS D+T R+W+
Sbjct: 228 LRGHESEVFICAWNPVSDLLASGSGDSTARIWN 260
>gi|20357529 guanine nucleotide-binding protein, beta-2 subunit
[Homo sapiens]
Length = 340
Score = 112 bits (280), Expect = 1e-24
Identities = 71/204 (34%), Positives = 100/204 (49%), Gaps = 5/204 (2%)
Query: 539 LYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPYGY 598
L GH+G + F D N +++SS D T LW ++T VG+ GH+ V +P G
Sbjct: 139 LPGHTGYLSCCRFLDD-NQIITSSGDTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGR 197
Query: 599 YFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLN 658
FVSG D +LW + F GH +D+N F PN TGS D T RL+D L
Sbjct: 198 TFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFD-LR 256
Query: 659 GNCVRIFTGHKG---PIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVC 715
+ + H I S+ FS +GR L G D +WD G G L GH + V
Sbjct: 257 ADQELLMYSHDNIICGITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDRAGVLAGHDNRVS 316
Query: 716 SLRFSRDGEILASGSMDNTVRLWD 739
L + DG +A+GS D+ +++W+
Sbjct: 317 CLGVTDDGMAVATGSWDSFLKIWN 340
Score = 103 bits (257), Expect = 6e-22
Identities = 61/215 (28%), Positives = 103/215 (47%), Gaps = 6/215 (2%)
Query: 537 KILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPY 596
+ L GH +Y + D L+S+S+DG + +W T + + V ++P
Sbjct: 49 RTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPS 108
Query: 597 GYYFVSGGHDRVARLWA----TDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVR 652
G + GG D + +++ + + R GH ++C RF + N + T S D T
Sbjct: 109 GNFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRF-LDDNQIITSSGDTTCA 167
Query: 653 LWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHTD 712
LWD+ G F GH G + SL+ +P+GR +GA D + LWD+ + GH
Sbjct: 168 LWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHES 227
Query: 713 TVCSLRFSRDGEILASGSMDNTVRLWDAIKAFEDL 747
+ ++ F +G +GS D T RL+D ++A ++L
Sbjct: 228 DINAVAFFPNGYAFTTGSDDATCRLFD-LRADQEL 261
Score = 80.9 bits (198), Expect = 4e-15
Identities = 47/188 (25%), Positives = 82/188 (43%), Gaps = 2/188 (1%)
Query: 512 DLSLIDKESDDVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWS 571
D + I S D + D +T + GHSG V S +PD +S + D +++LW
Sbjct: 153 DDNQIITSSGDTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWD 212
Query: 572 LQTFTCLVGYKGHNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFA--GHLAD 629
++ C + GH + F P GY F +G D RL+ Q L +++ +
Sbjct: 213 VRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRADQELLMYSHDNIICG 272
Query: 630 VNCTRFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGAT 689
+ F + + G D +WD + G+ + GH + L + +G +ATG+
Sbjct: 273 ITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDRAGVLAGHDNRVSCLGVTDDGMAVATGSW 332
Query: 690 DGRVLLWD 697
D + +W+
Sbjct: 333 DSFLKIWN 340
Score = 57.4 bits (137), Expect = 5e-08
Identities = 39/143 (27%), Positives = 64/143 (44%), Gaps = 9/143 (6%)
Query: 601 VSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLNGN 660
++ G D V R+ + R GHLA + + +S + + S D + +WD N
Sbjct: 33 ITAGLDPVGRI----QMRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTN 88
Query: 661 CVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDI----GHGLMVGELKGHTDTVCS 716
V + + ++P+G F+A G D ++ + G+ + EL GHT +
Sbjct: 89 KVHAIPLRSSWVMTCAYAPSGNFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSC 148
Query: 717 LRFSRDGEILASGSMDNTVRLWD 739
RF D +I+ S S D T LWD
Sbjct: 149 CRFLDDNQIITS-SGDTTCALWD 170
>gi|24431950 PRP4 pre-mRNA processing factor 4 homolog [Homo
sapiens]
Length = 522
Score = 112 bits (279), Expect = 2e-24
Identities = 63/201 (31%), Positives = 97/201 (48%), Gaps = 1/201 (0%)
Query: 541 GHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPYGYYF 600
GH+ V + P +L ++ D + RLW L+ ++ +GH+ V+D F G
Sbjct: 321 GHTVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLA 380
Query: 601 VSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLNGN 660
+GG D R+W + + GHL ++ F PN ++ATGS D T ++WD+
Sbjct: 381 GTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRR 440
Query: 661 CVRIFTGHKGPIHSLTFSP-NGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRF 719
CV H+ + + F P +G FL TGA D +W + L GH V L
Sbjct: 441 CVYTIPAHQNLVTGVKFEPIHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDI 500
Query: 720 SRDGEILASGSMDNTVRLWDA 740
S DG+++A+ S D T +LW A
Sbjct: 501 SSDGQLIATCSYDRTFKLWMA 521
Score = 110 bits (275), Expect = 5e-24
Identities = 60/195 (30%), Positives = 92/195 (47%), Gaps = 1/195 (0%)
Query: 545 PVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPYGYYFVSGG 604
P S P L S + DG+V+LWSL + + +GH V + P G + +
Sbjct: 283 PKSTVSLDPKDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTC 342
Query: 605 HDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLNGNCVRI 664
+DR RLW + + + GH V FH + + TG D R+WD+ G C+
Sbjct: 343 YDRSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMF 402
Query: 665 FTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSR-DG 723
GH I+ + FSPNG +ATG+ D +WD+ V + H + V ++F G
Sbjct: 403 LEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHG 462
Query: 724 EILASGSMDNTVRLW 738
L +G+ DNT ++W
Sbjct: 463 NFLLTGAYDNTAKIW 477
Score = 102 bits (254), Expect = 1e-21
Identities = 67/259 (25%), Positives = 110/259 (42%), Gaps = 15/259 (5%)
Query: 495 RVWSVTPKKLRSVKQASDLSLIDKESDDVLERIMDEKTASELKIL------YGHSGPVYG 548
R+W R++K+ + L KE + ++ L+ L G P+
Sbjct: 178 RLWIANYSLPRAMKRLEEARL-HKEIPETTRTSQMQELHKSLRSLNNFCSQIGDDRPISY 236
Query: 549 ASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHN--------YPVWDTQFSPYGYYF 600
FSP+ L ++ G +LWS+ L +GHN +P P
Sbjct: 237 CHFSPNSKMLATACWSGLCKLWSVPDCNLLHTLRGHNTNVGAIVFHPKSTVSLDPKDVNL 296
Query: 601 VSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLNGN 660
S D +LW+ D +P+ GH V +HP+ ++ T DR+ RLWD+
Sbjct: 297 ASCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQE 356
Query: 661 CVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFS 720
+ GH ++ + F +G TG D +WD+ G + L+GH + + FS
Sbjct: 357 EILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFS 416
Query: 721 RDGEILASGSMDNTVRLWD 739
+G +A+GS DNT ++WD
Sbjct: 417 PNGYHIATGSGDNTCKVWD 435
Score = 87.8 bits (216), Expect = 4e-17
Identities = 47/172 (27%), Positives = 82/172 (47%), Gaps = 1/172 (0%)
Query: 526 RIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHN 585
R+ D + E+ GHS VY +F D + + D R+W L+T C++ +GH
Sbjct: 348 RLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHL 407
Query: 586 YPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHP-NSNYVAT 644
++ FSP GY+ +G D ++W + + H V +F P + N++ T
Sbjct: 408 KEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHGNFLLT 467
Query: 645 GSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLW 696
G+ D T ++W + ++ GH+G + L S +G+ +AT + D LW
Sbjct: 468 GAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSDGQLIATCSYDRTFKLW 519
Score = 83.2 bits (204), Expect = 9e-16
Identities = 44/144 (30%), Positives = 70/144 (48%), Gaps = 1/144 (0%)
Query: 512 DLSLIDKESDDVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWS 571
D SL D R+ D +T + L GH +YG +FSP+ ++ + S D T ++W
Sbjct: 376 DGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWD 435
Query: 572 LQTFTCLVGYKGHNYPVWDTQFSP-YGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADV 630
L+ C+ H V +F P +G + ++G +D A++W + PL+ AGH V
Sbjct: 436 LRQRRCVYTIPAHQNLVTGVKFEPIHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKV 495
Query: 631 NCTRFHPNSNYVATGSADRTVRLW 654
+ +AT S DRT +LW
Sbjct: 496 MGLDISSDGQLIATCSYDRTFKLW 519
Score = 42.4 bits (98), Expect = 0.002
Identities = 35/156 (22%), Positives = 61/156 (39%), Gaps = 12/156 (7%)
Query: 472 GLTAVDVTDDSSLIAGGFADSTVRVWSVTP-----------KKLRSVKQASDLSLIDKES 520
G+ + D SL G D+ RVW + K++ + + + I S
Sbjct: 367 GVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPNGYHIATGS 426
Query: 521 DDVLERIMDEKTASELKILYGHSGPVYGASFSPDR-NYLLSSSEDGTVRLWSLQTFTCLV 579
D ++ D + + + H V G F P N+LL+ + D T ++W+ ++ L
Sbjct: 427 GDNTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHGNFLLTGAYDNTAKIWTHPGWSPLK 486
Query: 580 GYKGHNYPVWDTQFSPYGYYFVSGGHDRVARLWATD 615
GH V S G + +DR +LW +
Sbjct: 487 TLAGHEGKVMGLDISSDGQLIATCSYDRTFKLWMAE 522
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.133 0.392
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,459,964
Number of Sequences: 37866
Number of extensions: 1859763
Number of successful extensions: 23444
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 438
Number of HSP's successfully gapped in prelim test: 753
Number of HSP's that attempted gapping in prelim test: 13107
Number of HSP's gapped (non-prelim): 6859
length of query: 800
length of database: 18,247,518
effective HSP length: 110
effective length of query: 690
effective length of database: 14,082,258
effective search space: 9716758020
effective search space used: 9716758020
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.