Guide to the Human Genome
Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Search of human proteins with 210147522

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|210147522 zinc finger, SWIM-type containing 6 [Homo sapiens]
         (1215 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|210147522 zinc finger, SWIM-type containing 6 [Homo sapiens]      2456   0.0  
gi|149944451 zinc finger, SWIM domain containing 5 [Homo sapiens]    1726   0.0  
gi|190885491 zinc finger, SWIM-type containing 4 [Homo sapiens]       781   0.0  
gi|122114658 hypothetical protein LOC23053 [Homo sapiens]             186   9e-47
gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2 ...    68   6e-11
gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1 ...    68   6e-11
gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3 ...    68   6e-11
gi|22748877 basic helix-loop-helix domain containing, class B, 5...    64   1e-09
gi|109255251 loricrin [Homo sapiens]                                   63   1e-09
gi|12707580 paired-like homeobox 2b [Homo sapiens]                     62   3e-09
gi|195972866 keratin 10 [Homo sapiens]                                 58   5e-08
gi|110347449 POU domain, class 4, transcription factor 1 [Homo s...    57   1e-07
gi|109452587 family with sequence similarity 98, member B isofor...    56   2e-07
gi|49574532 glycogen synthase kinase 3 alpha [Homo sapiens]            55   5e-07
gi|89257348 homeo box HB9 [Homo sapiens]                               54   9e-07
gi|24432032 zinc finger protein 503 [Homo sapiens]                     52   3e-06
gi|119220564 one cut domain, family member 2 [Homo sapiens]            52   3e-06
gi|33188461 GATA binding protein 4 [Homo sapiens]                      52   4e-06
gi|4507163 SRY (sex determining region Y)-box 4 [Homo sapiens]         52   4e-06
gi|18375613 dachshund homolog 1 isoform b [Homo sapiens]               52   4e-06
gi|18375611 dachshund homolog 1 isoform a [Homo sapiens]               52   4e-06
gi|18375609 dachshund homolog 1 isoform c [Homo sapiens]               52   4e-06
gi|45439359 triple functional domain (PTPRF interacting) [Homo s...    52   4e-06
gi|20127580 BTB (POZ) domain containing 2 [Homo sapiens]               52   4e-06
gi|8051631 RNA binding protein (autoantigenic, hnRNP-associated ...    52   4e-06
gi|21396480 RNA binding protein (autoantigenic, hnRNP-associated...    52   4e-06
gi|23510368 homeobox D11 [Homo sapiens]                                51   6e-06
gi|30179900 SRY (sex determining region Y)-box 1 [Homo sapiens]        51   6e-06
gi|73476377 LBXCOR1 homolog [Homo sapiens]                             51   6e-06
gi|84570137 homeobox B3 [Homo sapiens]                                 51   8e-06

>gi|210147522 zinc finger, SWIM-type containing 6 [Homo sapiens]
          Length = 1215

 Score = 2456 bits (6364), Expect = 0.0
 Identities = 1215/1215 (100%), Positives = 1215/1215 (100%)

Query: 1    MAERGQQPPPAKRLCCRPGGGGGGGGSSGGGGGAGGGYSSACRPGPRAGGAAAAAACGGG 60
            MAERGQQPPPAKRLCCRPGGGGGGGGSSGGGGGAGGGYSSACRPGPRAGGAAAAAACGGG
Sbjct: 1    MAERGQQPPPAKRLCCRPGGGGGGGGSSGGGGGAGGGYSSACRPGPRAGGAAAAAACGGG 60

Query: 61   AALGLLPPGKTQSPESLLDIAARRVAEKWPFQRVEERFERIPEPVQRRIVYWSFPRSERE 120
            AALGLLPPGKTQSPESLLDIAARRVAEKWPFQRVEERFERIPEPVQRRIVYWSFPRSERE
Sbjct: 61   AALGLLPPGKTQSPESLLDIAARRVAEKWPFQRVEERFERIPEPVQRRIVYWSFPRSERE 120

Query: 121  ICMYSSFNTGGGAAGGPGDDSGGGGGAGGGGGGGSSSSPAATSAAATSAAAAAAAAAAAA 180
            ICMYSSFNTGGGAAGGPGDDSGGGGGAGGGGGGGSSSSPAATSAAATSAAAAAAAAAAAA
Sbjct: 121  ICMYSSFNTGGGAAGGPGDDSGGGGGAGGGGGGGSSSSPAATSAAATSAAAAAAAAAAAA 180

Query: 181  AAAAGAGAPSVGAAGAADGGDETRLPFRRGIALLESGCVDNVLQVGFHLSGTVTEPAIQS 240
            AAAAGAGAPSVGAAGAADGGDETRLPFRRGIALLESGCVDNVLQVGFHLSGTVTEPAIQS
Sbjct: 181  AAAAGAGAPSVGAAGAADGGDETRLPFRRGIALLESGCVDNVLQVGFHLSGTVTEPAIQS 240

Query: 241  EPETVCNVAISFDRCKITSVTCSCGNKDIFYCAHVVALSLYRIRKPDQVKLHLPISETLF 300
            EPETVCNVAISFDRCKITSVTCSCGNKDIFYCAHVVALSLYRIRKPDQVKLHLPISETLF
Sbjct: 241  EPETVCNVAISFDRCKITSVTCSCGNKDIFYCAHVVALSLYRIRKPDQVKLHLPISETLF 300

Query: 301  QMNRDQLQKFVQYLITVHHTEVLPTAQKLADEILSQNSEINQVHGAPDPTAGASIDDENC 360
            QMNRDQLQKFVQYLITVHHTEVLPTAQKLADEILSQNSEINQVHGAPDPTAGASIDDENC
Sbjct: 301  QMNRDQLQKFVQYLITVHHTEVLPTAQKLADEILSQNSEINQVHGAPDPTAGASIDDENC 360

Query: 361  WHLDEEQVQEQVKLFLSQGGYHGSGKQLNLLFAKVREMLKMRDSNGARMLTLITEQFMAD 420
            WHLDEEQVQEQVKLFLSQGGYHGSGKQLNLLFAKVREMLKMRDSNGARMLTLITEQFMAD
Sbjct: 361  WHLDEEQVQEQVKLFLSQGGYHGSGKQLNLLFAKVREMLKMRDSNGARMLTLITEQFMAD 420

Query: 421  PRLSLWRQQGTAMTDKYRQLWDELGALWMCIVLNPHCKLEQKASWLKQLKKWNSVDVCPW 480
            PRLSLWRQQGTAMTDKYRQLWDELGALWMCIVLNPHCKLEQKASWLKQLKKWNSVDVCPW
Sbjct: 421  PRLSLWRQQGTAMTDKYRQLWDELGALWMCIVLNPHCKLEQKASWLKQLKKWNSVDVCPW 480

Query: 481  EDGNHGSELPNLTNALPQGANANQDSSNRPHRTVFTRAIEACDLHWQDSHLQHIISSDLY 540
            EDGNHGSELPNLTNALPQGANANQDSSNRPHRTVFTRAIEACDLHWQDSHLQHIISSDLY
Sbjct: 481  EDGNHGSELPNLTNALPQGANANQDSSNRPHRTVFTRAIEACDLHWQDSHLQHIISSDLY 540

Query: 541  TNYCYHDDTENSLFDSRGWPLWHEHVPTACARVDALRSHGYPREALRLAIAIVNTLRRQQ 600
            TNYCYHDDTENSLFDSRGWPLWHEHVPTACARVDALRSHGYPREALRLAIAIVNTLRRQQ
Sbjct: 541  TNYCYHDDTENSLFDSRGWPLWHEHVPTACARVDALRSHGYPREALRLAIAIVNTLRRQQ 600

Query: 601  QKQLEMFRTQKKELPHKNITSITNLEGWVGHPLDPVGTLFSSLMEACRIDDENLSGFSDF 660
            QKQLEMFRTQKKELPHKNITSITNLEGWVGHPLDPVGTLFSSLMEACRIDDENLSGFSDF
Sbjct: 601  QKQLEMFRTQKKELPHKNITSITNLEGWVGHPLDPVGTLFSSLMEACRIDDENLSGFSDF 660

Query: 661  TENMGQCKSLEYQHLPAHKFLEEGESYLTLAVEVALIGLGQQRIMPDGLYTQEKVCRNEE 720
            TENMGQCKSLEYQHLPAHKFLEEGESYLTLAVEVALIGLGQQRIMPDGLYTQEKVCRNEE
Sbjct: 661  TENMGQCKSLEYQHLPAHKFLEEGESYLTLAVEVALIGLGQQRIMPDGLYTQEKVCRNEE 720

Query: 721  QLISKLQEIELDDTLVKIFRKQAVFLLEAGPYSGLGEIIHRESVPMHTFAKYLFTSLLPH 780
            QLISKLQEIELDDTLVKIFRKQAVFLLEAGPYSGLGEIIHRESVPMHTFAKYLFTSLLPH
Sbjct: 721  QLISKLQEIELDDTLVKIFRKQAVFLLEAGPYSGLGEIIHRESVPMHTFAKYLFTSLLPH 780

Query: 781  DAELAYKIALRAMRLLVLESTAPSGDLTRPHHIASVVPNRYPRWFTLSHIESQQCELAST 840
            DAELAYKIALRAMRLLVLESTAPSGDLTRPHHIASVVPNRYPRWFTLSHIESQQCELAST
Sbjct: 781  DAELAYKIALRAMRLLVLESTAPSGDLTRPHHIASVVPNRYPRWFTLSHIESQQCELAST 840

Query: 841  MLTAAKGDVRRLETVLESIQKNIHSSSHIFKLAQDAFKIATLMDSLPDITLLKVSLELGL 900
            MLTAAKGDVRRLETVLESIQKNIHSSSHIFKLAQDAFKIATLMDSLPDITLLKVSLELGL
Sbjct: 841  MLTAAKGDVRRLETVLESIQKNIHSSSHIFKLAQDAFKIATLMDSLPDITLLKVSLELGL 900

Query: 901  QVMRMTLSTLNWRRREMVRWLVTCATEVGVYALDSIMQTWFTLFTPTEATSIVATTVMSN 960
            QVMRMTLSTLNWRRREMVRWLVTCATEVGVYALDSIMQTWFTLFTPTEATSIVATTVMSN
Sbjct: 901  QVMRMTLSTLNWRRREMVRWLVTCATEVGVYALDSIMQTWFTLFTPTEATSIVATTVMSN 960

Query: 961  STIVRLHLDCHQQEKLASSARTLALQCAMKDPQNCALSALTLCEKDHIAFETAYQIVLDA 1020
            STIVRLHLDCHQQEKLASSARTLALQCAMKDPQNCALSALTLCEKDHIAFETAYQIVLDA
Sbjct: 961  STIVRLHLDCHQQEKLASSARTLALQCAMKDPQNCALSALTLCEKDHIAFETAYQIVLDA 1020

Query: 1021 ATTGMSYTQLFTIARYMEHRGYPMRAYKLATLAMTHLNLSYNQDTHPAINDVLWACALSH 1080
            ATTGMSYTQLFTIARYMEHRGYPMRAYKLATLAMTHLNLSYNQDTHPAINDVLWACALSH
Sbjct: 1021 ATTGMSYTQLFTIARYMEHRGYPMRAYKLATLAMTHLNLSYNQDTHPAINDVLWACALSH 1080

Query: 1081 SLGKNELAAIIPLVVKSVKCATVLSDILRRCTLTTPGMVGLHGRRNSGKLMSLDKAPLRQ 1140
            SLGKNELAAIIPLVVKSVKCATVLSDILRRCTLTTPGMVGLHGRRNSGKLMSLDKAPLRQ
Sbjct: 1081 SLGKNELAAIIPLVVKSVKCATVLSDILRRCTLTTPGMVGLHGRRNSGKLMSLDKAPLRQ 1140

Query: 1141 LLDATIGAYINTTHSRLTHISPRHYSEFIEFLSKARETFLMAHDGHIQFTQFIDNLKQIY 1200
            LLDATIGAYINTTHSRLTHISPRHYSEFIEFLSKARETFLMAHDGHIQFTQFIDNLKQIY
Sbjct: 1141 LLDATIGAYINTTHSRLTHISPRHYSEFIEFLSKARETFLMAHDGHIQFTQFIDNLKQIY 1200

Query: 1201 KGKKKLMMLVRERFG 1215
            KGKKKLMMLVRERFG
Sbjct: 1201 KGKKKLMMLVRERFG 1215


>gi|149944451 zinc finger, SWIM domain containing 5 [Homo sapiens]
          Length = 1185

 Score = 1726 bits (4469), Expect = 0.0
 Identities = 876/1208 (72%), Positives = 988/1208 (81%), Gaps = 42/1208 (3%)

Query: 10   PAKRLCCRPGGGGGGG-GSSGGGGGAGGGYSSACRPGPRAGGAAAAAACGGGAALGLLPP 68
            PAKR C  P        GS G  GG  GG  S+C                    LG  P 
Sbjct: 18   PAKRQCSWPSPQAHHPRGSPGAAGGGAGGVGSSC------------------LVLGARP- 58

Query: 69   GKTQSPESLLDIAARRVAEKWPFQRVEERFERIPEPVQRRIVYWSFPRSEREICMYSSFN 128
                 P+SLLD AA+ VAEKW ++RVEERFERIPEPVQRRIVYWSFPR+EREICMYSSF 
Sbjct: 59   --HLQPDSLLDCAAKTVAEKWAYERVEERFERIPEPVQRRIVYWSFPRNEREICMYSSFQ 116

Query: 129  TGGGAAGGPGDDSGGGGGAGGGGGGGSSSSPAATSAAATSAAAAAAAAAAAAAAAAGAGA 188
                  GGPG  +G  GGA G         P   +AA   +A    AA A+    AGAGA
Sbjct: 117  ----YRGGPG--AGAAGGAAGASPAEEGPQPPPGAAAPAGSAPGGVAAGASPGLGAGAGA 170

Query: 189  PSVGAAGAADGGDETRLPFRRGIALLESGCVDNVLQVGFHLSGTVTEPAIQSEPETVCNV 248
               G  G         LPFRRGI LL+SG V+NVLQVGFHLSGTVTE A  SEP     V
Sbjct: 171  AGCGGEG---------LPFRRGIRLLDSGSVENVLQVGFHLSGTVTELATASEPAVTYKV 221

Query: 249  AISFDRCKITSVTCSCGNKDIFYCAHVVALSLYRIRKPDQVKLHLPISETLFQMNRDQLQ 308
            AISFDRCKITSVTC CGNKDIFYCAHVVALSLYRIRKPDQVKL LPISETLFQMNRDQLQ
Sbjct: 222  AISFDRCKITSVTCGCGNKDIFYCAHVVALSLYRIRKPDQVKLRLPISETLFQMNRDQLQ 281

Query: 309  KFVQYLITVHHTEVLPTAQKLADEILSQNSEINQVHGAPDPTAGASIDDENCWHLDEEQV 368
            KF+QYLIT HHTEVLPTAQKLADEILS NSEINQV+GAPDPTAGASIDDENCWHLDEEQV
Sbjct: 282  KFIQYLITAHHTEVLPTAQKLADEILSSNSEINQVNGAPDPTAGASIDDENCWHLDEEQV 341

Query: 369  QEQVKLFLSQGGYHGSGKQLNLLFAKVREMLKMRDSNGARMLTLITEQFMADPRLSLWRQ 428
            +EQVKLFLSQGGY GSGKQLN +FAKVREML+MRDSNGARMLTLITEQF+ADPRL+LWRQ
Sbjct: 342  KEQVKLFLSQGGYCGSGKQLNSMFAKVREMLRMRDSNGARMLTLITEQFVADPRLTLWRQ 401

Query: 429  QGTAMTDKYRQLWDELGALWMCIVLNPHCKLEQKASWLKQLKKWNSVDVCPWEDGNHGSE 488
            QGT MTDK RQLWDELGALW+CI+LNPHCKLE+K+ WL+QL+KW+ +DVCP EDGN+G E
Sbjct: 402  QGTNMTDKCRQLWDELGALWVCIILNPHCKLEEKSCWLQQLQKWSDLDVCPLEDGNYGHE 461

Query: 489  LPNLTNALPQGANANQDSSNRPHRTVFTRAIEACDLHWQDSHLQHIISSDLYTNYCYHDD 548
            LPN+TNALPQ A  + DS +RP RTVFTRAIE  +LHWQDSHLQ IISSD+YT      +
Sbjct: 462  LPNITNALPQSAIHSPDSLSRPRRTVFTRAIEGRELHWQDSHLQRIISSDVYTAPACQRE 521

Query: 549  TENSLFDSRGWPLWHEHVPTACARVDALRSHGYPREALRLAIAIVNTLRRQQQKQLEMFR 608
            +E  LF+S+G PLW EHVPTACARVDALRSHGYP+EALRL +AI+NTLR QQQ+QLE+++
Sbjct: 522  SERLLFNSQGQPLWLEHVPTACARVDALRSHGYPKEALRLTVAIINTLRLQQQRQLEIYK 581

Query: 609  TQKKELPHKNITSITNLEGWVGHPLDPVGTLFSSLMEACRIDDENLSGFSDFTENMGQCK 668
             QKKEL  +  T+ITNLEGWVGHPLDP+  LF +L EACR++D+     SD    M + +
Sbjct: 582  HQKKELLQRGTTTITNLEGWVGHPLDPIDCLFLTLTEACRLNDDGYLEMSD----MNESR 637

Query: 669  SLEYQHLP-AHKFLEEGESYLTLAVEVALIGLGQQRIMPDGLYTQEKVCRNEEQLISKLQ 727
               YQH+P A       ESYL+LA+EVAL+GLGQQR+MP+GLY Q+KVCRNEEQL+S+LQ
Sbjct: 638  PPVYQHVPVAAGSPNSSESYLSLALEVALMGLGQQRLMPEGLYAQDKVCRNEEQLLSQLQ 697

Query: 728  EIELDDTLVKIFRKQAVFLLEAGPYSGLGEIIHRESVPMHTFAKYLFTSLLPHDAELAYK 787
            E++LDD LV+  +KQ + LLE GP+SGLGE+IHRESVPMHTFAKYLF++LLPHD +L+YK
Sbjct: 698  ELQLDDELVQTLQKQCILLLEGGPFSGLGEVIHRESVPMHTFAKYLFSALLPHDPDLSYK 757

Query: 788  IALRAMRLLVLESTAPSGDLTRPHHIASVVPNRYPRWFTLSHIESQQCELASTMLTAAKG 847
            +ALRAMRL VLE++A +GD + PHH+ SVVP+RYPRWFTL H+ESQQCELASTMLTAAKG
Sbjct: 758  LALRAMRLPVLENSASAGDTSHPHHMVSVVPSRYPRWFTLGHLESQQCELASTMLTAAKG 817

Query: 848  DVRRLETVLESIQKNIHSSSHIFKLAQDAFKIATLMDSLPDITLLKVSLELGLQVMRMTL 907
            D  RL T+LE+IQK+IHSSS IFKLAQDAFKIAT  DS  D TLL V+LELGLQVMRMTL
Sbjct: 818  DTLRLRTILEAIQKHIHSSSLIFKLAQDAFKIATPTDSSTDSTLLNVALELGLQVMRMTL 877

Query: 908  STLNWRRREMVRWLVTCATEVGVYALDSIMQTWFTLFTPTEATSIVATTVMSNSTIVRLH 967
            STLNWRRREMVRWLVTCATEVGV AL SI+Q+W+TLFTPTEATSIVA T +S++TI+RL 
Sbjct: 878  STLNWRRREMVRWLVTCATEVGVRALVSILQSWYTLFTPTEATSIVAATAVSHTTILRLS 937

Query: 968  LDCHQQEKLASSARTLALQCAMKDPQNCALSALTLCEKDHIAFETAYQIVLDAATTGMSY 1027
            LD  Q+E+LAS ARTLALQCAMKDPQ+CALSALTLCEKDHIAFE AYQI +DAA  GM++
Sbjct: 938  LDYPQREELASCARTLALQCAMKDPQSCALSALTLCEKDHIAFEAAYQIAIDAAAGGMTH 997

Query: 1028 TQLFTIARYMEHRGYPMRAYKLATLAMTHLNLSYNQDTHPAINDVLWACALSHSLGKNEL 1087
            +QLFTIARYME RGYP+RA+KLA+LAM+HLNL+YNQDTHPAINDVLWACALSHSLGKNEL
Sbjct: 998  SQLFTIARYMELRGYPLRAFKLASLAMSHLNLAYNQDTHPAINDVLWACALSHSLGKNEL 1057

Query: 1088 AAIIPLVVKSVKCATVLSDILRRCTLTTPGMVGLHGRRNSGKLMSLDKAPLRQLLDATIG 1147
            AA+IPLVVKSV CATVLSDILRRCT+T PG+ G+ GRR+SGKLMS DKAPLRQLLDATI 
Sbjct: 1058 AALIPLVVKSVHCATVLSDILRRCTVTAPGLAGIPGRRSSGKLMSTDKAPLRQLLDATIN 1117

Query: 1148 AYINTTHSRLTHISPRHYSEFIEFLSKARETFLMAHDGHIQFTQFIDNLKQIYKGKKKLM 1207
            AYINTTHSRLTHISPRHY EFIEFLSKARETFL+  DGH+QF QFIDNLKQIYKGKKKLM
Sbjct: 1118 AYINTTHSRLTHISPRHYGEFIEFLSKARETFLLPQDGHLQFAQFIDNLKQIYKGKKKLM 1177

Query: 1208 MLVRERFG 1215
            +LVRERFG
Sbjct: 1178 LLVRERFG 1185



 Score = 35.8 bits (81), Expect = 0.25
 Identities = 20/60 (33%), Positives = 25/60 (41%)

Query: 8   PPPAKRLCCRPGGGGGGGGSSGGGGGAGGGYSSACRPGPRAGGAAAAAACGGGAALGLLP 67
           P   + +C        GG  +G  GGA G   +   P P  G AA A +  GG A G  P
Sbjct: 103 PRNEREICMYSSFQYRGGPGAGAAGGAAGASPAEEGPQPPPGAAAPAGSAPGGVAAGASP 162



 Score = 34.7 bits (78), Expect = 0.57
 Identities = 21/58 (36%), Positives = 25/58 (43%), Gaps = 17/58 (29%)

Query: 2   AERGQQPPPAKRLCCRPGGGGGGGGSSGGGGGAGGGYSSACRPGPRAGGAAAAAACGG 59
           AE G QPPP               G++   G A GG ++   PG   G  A AA CGG
Sbjct: 135 AEEGPQPPP---------------GAAAPAGSAPGGVAAGASPG--LGAGAGAAGCGG 175


>gi|190885491 zinc finger, SWIM-type containing 4 [Homo sapiens]
          Length = 989

 Score =  781 bits (2016), Expect = 0.0
 Identities = 384/603 (63%), Positives = 489/603 (81%), Gaps = 7/603 (1%)

Query: 613  ELPHKNITSITNLEGWVGHPLDPVGTLFSSLMEACRIDDENLSGFSDFTENMGQCKSLEY 672
            EL  K  T ITN EGWVGHPLDP+G L  +L+EACR+++E L+ + D   +  + + + Y
Sbjct: 394  ELLQKGSTCITNTEGWVGHPLDPIGCLCRALLEACRLEEETLTLYPD---SGPEKRKVAY 450

Query: 673  QHLPAHKFLEEGESYLTLAVEVALIGLGQQRIMPDGLYTQEKVCRNEEQLISKLQEIELD 732
            QH+P       GESYL LA+EVAL+GLGQQR +P+GLY Q+KV RNEEQL++ L+E+ELD
Sbjct: 451  QHVPVPG--SPGESYLVLALEVALLGLGQQRALPEGLYAQDKVVRNEEQLLALLEEVELD 508

Query: 733  DTLVKIFRKQAVFLLEAGPYSGLGEIIHRESVPMHTFAKYLFTSLLPHDAELAYKIALRA 792
            + LV++ RKQA  LLE GP+SG GE++ RESVPMHT A+YLFT+LLPHD +LAY++ALRA
Sbjct: 509  ERLVQVLRKQAGLLLEGGPFSGFGEVLFRESVPMHTCARYLFTALLPHDPDLAYRLALRA 568

Query: 793  MRLLVLESTAPSGDLTRPHHIASVVPNRYPRWFTLSHIESQQCELASTMLTAAKGDVRRL 852
            MRL +LE+  P+G+   P  + S++ NR+PRWF L H+E++QCELASTMLTAAKGD + L
Sbjct: 569  MRLPILETAFPAGE-PHPSPLDSIMSNRFPRWFILGHLETRQCELASTMLTAAKGDPKWL 627

Query: 853  ETVLESIQKNIHSSSHIFKLAQDAFKIATLMDSLPDITLLKVSLELGLQVMRMTLSTLNW 912
             TVL SIQ+NIHS + +FKLAQDA K AT + + PD TLL ++LELGLQVMRMTL+ + W
Sbjct: 628  HTVLGSIQQNIHSPALLFKLAQDACKTATPVSAPPDTTLLGIALELGLQVMRMTLNVMTW 687

Query: 913  RRREMVRWLVTCATEVGVYALDSIMQTWFTLFTPTEATSIVATTVMSNSTIVRLHLDCHQ 972
            RRREMVRWLV+CATE+G  AL +IMQ W++LFTP EA +IVA T  +++T++RL LD  +
Sbjct: 688  RRREMVRWLVSCATEIGPQALMNIMQNWYSLFTPVEAATIVAVTGTTHATLLRLQLDTSR 747

Query: 973  QEKLASSARTLALQCAMKDPQNCALSALTLCEKDHIAFETAYQIVLDAATTGMSYTQLFT 1032
            +E+L + ARTLALQCAMKDPQNCAL ALTLCEK+H AFE AYQIVLDAA  G+ +  LFT
Sbjct: 748  REELWACARTLALQCAMKDPQNCALPALTLCEKNHSAFEAAYQIVLDAAAGGLGHAHLFT 807

Query: 1033 IARYMEHRGYPMRAYKLATLAMTHLNLSYNQDTHPAINDVLWACALSHSLGKNELAAIIP 1092
            +ARYMEHRG P+RAYKLATLA+  L++++NQD+HPA+NDVLWAC+LSHSLG++EL+AI+P
Sbjct: 808  VARYMEHRGLPLRAYKLATLALAQLSIAFNQDSHPAVNDVLWACSLSHSLGRHELSAIVP 867

Query: 1093 LVVKSVKCATVLSDILRRCTLTTPGMVGLHGRRNSGKLMSLDKAPLRQLLDATIGAYINT 1152
            L+++S+ CA +LSDILRR TL+ PG+ G  G R + K +  D+APL QLLDA + AYI T
Sbjct: 868  LIIRSIHCAPMLSDILRRWTLSAPGL-GPLGARRAAKPLGADRAPLCQLLDAAVTAYITT 926

Query: 1153 THSRLTHISPRHYSEFIEFLSKARETFLMAHDGHIQFTQFIDNLKQIYKGKKKLMMLVRE 1212
            +HSRLTHISPRHY +FIEFL KARETFL+A DGH+QF+QF++NLKQ YKGKKKLM+LVRE
Sbjct: 927  SHSRLTHISPRHYGDFIEFLGKARETFLLAPDGHLQFSQFLENLKQTYKGKKKLMLLVRE 986

Query: 1213 RFG 1215
            RFG
Sbjct: 987  RFG 989



 Score =  437 bits (1124), Expect = e-122
 Identities = 205/295 (69%), Positives = 245/295 (83%)

Query: 198 DGGDETRLPFRRGIALLESGCVDNVLQVGFHLSGTVTEPAIQSEPETVCNVAISFDRCKI 257
           +G  + R+PF RG+ LL+SG VD VLQVGFHLSG + EP    EPE + +V+ISFDRCKI
Sbjct: 91  EGEHDARVPFTRGLHLLQSGAVDRVLQVGFHLSGNIREPGSPGEPERLYHVSISFDRCKI 150

Query: 258 TSVTCSCGNKDIFYCAHVVALSLYRIRKPDQVKLHLPISETLFQMNRDQLQKFVQYLITV 317
           TSV+C C N+D+FYCAHVVALSLYRIR   QV+L LPISETL QMNRDQLQKFVQYLI+ 
Sbjct: 151 TSVSCGCDNRDLFYCAHVVALSLYRIRHAHQVELRLPISETLSQMNRDQLQKFVQYLISA 210

Query: 318 HHTEVLPTAQKLADEILSQNSEINQVHGAPDPTAGASIDDENCWHLDEEQVQEQVKLFLS 377
           HHTEVLPTAQ+LADEIL   SEIN V+GAPDPTAGA I+D NCWHLDEEQ+QEQVK  LS
Sbjct: 211 HHTEVLPTAQRLADEILLLGSEINLVNGAPDPTAGAGIEDANCWHLDEEQIQEQVKQLLS 270

Query: 378 QGGYHGSGKQLNLLFAKVREMLKMRDSNGARMLTLITEQFMADPRLSLWRQQGTAMTDKY 437
            GGY+G+ +QL  +F+KVREML+MRDSNGARML L+TEQF+ D RL+LWRQQG  MTDK 
Sbjct: 271 NGGYYGASQQLRSMFSKVREMLRMRDSNGARMLILMTEQFLQDTRLALWRQQGAGMTDKC 330

Query: 438 RQLWDELGALWMCIVLNPHCKLEQKASWLKQLKKWNSVDVCPWEDGNHGSELPNL 492
           RQLWDELGALW+C+VL+PHCK E++A WL+ L +W+ +DVCP E+GN+  + P+L
Sbjct: 331 RQLWDELGALWVCVVLSPHCKPEERAGWLQLLSRWDKLDVCPLEEGNYSFDGPSL 385



 Score =  102 bits (254), Expect = 2e-21
 Identities = 51/88 (57%), Positives = 60/88 (68%), Gaps = 12/88 (13%)

Query: 39  SSACRPGPRAGGAAAAAACGGGAALGLLPPGKTQSPESLLDIAARRVAEKWPFQRVEERF 98
           S  C  GP    A A AA G G             PE+LLD++A+RVAE W F++VEERF
Sbjct: 9   SRGCPAGPEERDAGAGAARGRGR------------PEALLDLSAKRVAESWAFEQVEERF 56

Query: 99  ERIPEPVQRRIVYWSFPRSEREICMYSS 126
            R+PEPVQ+RIV+WSFPRSEREICMYSS
Sbjct: 57  SRVPEPVQKRIVFWSFPRSEREICMYSS 84


>gi|122114658 hypothetical protein LOC23053 [Homo sapiens]
          Length = 1842

 Score =  186 bits (473), Expect = 9e-47
 Identities = 143/487 (29%), Positives = 207/487 (42%), Gaps = 94/487 (19%)

Query: 113 SFPRSEREICMYSSFNTGGGAAGGPGDDSGGGGGAGGGGGGGSSSSPAATSAAATSAAAA 172
           SF      +C     N  G      G +S  GGG GGG GG              SA   
Sbjct: 29  SFISEAESLCQ----NWRGWRKQSAGPNSPTGGGGGGGSGGTRMRDGLVIPLVELSAKQV 84

Query: 173 AAAAAAAAAAAAGAGAPS-----VGAAGAADGGDETRL----------PFRRGIALLESG 217
           A               P      +      +  ++ RL           F+RG  L    
Sbjct: 85  AFHIPFEVVEKVYPPVPEQLQLRIAFWSFPENEEDIRLYSCLANGSADEFQRGDQLFRMR 144

Query: 218 CVDNVLQVGFHLSGTVTEPAIQSEPETVCNVAISFDRCKITSVTCSCGNKDIFYCAHVVA 277
            V + LQ+GFHLS TV  P +   P+   NVA+ FDRC++TS +C+CG     +C HVVA
Sbjct: 145 AVKDPLQIGFHLSATVVPPQMVP-PKGAYNVAVMFDRCRVTSCSCTCG-AGAKWCTHVVA 202

Query: 278 LSLYRIRKPDQVKLHLPISETLFQMNRDQLQKFVQYLITVHHTEVLPTAQKLADEIL-SQ 336
           L L+RI     V L  P+SE+L ++ RDQLQKF QYLI+    ++LPTAQ+L DE+L SQ
Sbjct: 203 LCLFRIHNASAVCLRAPVSESLSRLQRDQLQKFAQYLISELPQQILPTAQRLLDELLSSQ 262

Query: 337 NSEINQVHGAPDPTAGASIDDENCWHLDEEQVQEQVK-------------------LFLS 377
           ++ IN V GAPDPTAG S  D++ W+LDE  + + +K                   ++LS
Sbjct: 263 STAINTVCGAPDPTAGPSASDQSTWYLDESTLTDNIKKTLHKFCGPSPVVFSDVNSMYLS 322

Query: 378 QGGYHGSGKQLNL--------------LFAKVREMLKMRDSNGARMLTLITEQFMADPRL 423
                 + +   L              L + VREM K RDSN A +L ++T+Q +   ++
Sbjct: 323 STEPPAAAEWACLLRPLRGREPEGVWNLLSIVREMFKRRDSNAAPLLEILTDQCLTYEQI 382

Query: 424 SLW--------------------RQQGTAMTDKYRQLWDELGALWMCIVLNPHCKLEQKA 463
           + W                      Q          + DE+  LW   VL+P    +++ 
Sbjct: 383 TGWWYSVRTSASHSSASGHTGRSNGQSEVAAHACASMCDEMVTLWRLAVLDPALSPQRRR 442

Query: 464 SWLKQLKKWNSVDVCPWEDGNHGSELPNLTNALPQGANANQDSSNRPHRTVFTRAIEACD 523
               QL++W    +   + G H   L  L                      F  A+EAC 
Sbjct: 443 ELCTQLRQWQLKVIENVKRGQHKKTLERLFPG-------------------FRPAVEACY 483

Query: 524 LHWQDSH 530
            +W++++
Sbjct: 484 FNWEEAY 490



 Score = 55.8 bits (133), Expect = 2e-07
 Identities = 43/166 (25%), Positives = 68/166 (40%), Gaps = 16/166 (9%)

Query: 1046 AYKLATLAMTHLNLSYNQD-------THPAINDVLWACALSHSLGKNELAAIIPLVVKSV 1098
            AY++  LA+  L    + D       + P  +DV W   L+  LG N +        K V
Sbjct: 1672 AYRVGMLALEMLGRRAHNDHPNNFSRSPPYTDDVKWLLGLAAKLGVNYVHQFCVGAAKGV 1731

Query: 1099 KCATVLSDILRRCTLTTPGMVGLHGRRNSGKLMSLDKAPLRQLLDATIGAYINTTHSRLT 1158
                VL +I+     T   +   H   +      L      QL+     AY+   H RL 
Sbjct: 1732 LSPFVLQEIVME---TLQRLSPAHAHNH------LRAPAFHQLVQRCQQAYMQYIHHRLI 1782

Query: 1159 HISPRHYSEFIEFLSKARETFLMAHDGHIQFTQFIDNLKQIYKGKK 1204
            H++P  Y +F+  +  AR  F +   G +QF   + NLK+  + K+
Sbjct: 1783 HLTPADYDDFVNAIRSARSAFCLTPMGMMQFNDILQNLKRSKQTKE 1828



 Score = 54.3 bits (129), Expect = 7e-07
 Identities = 32/104 (30%), Positives = 50/104 (48%), Gaps = 8/104 (7%)

Query: 36  GGYSSACRPGPRAGGAAAAAACGGGAALGLLPPGKTQSPESLLDIAARRVAEKWPFQRVE 95
           G    +  P    GG     + G     GL+ P        L++++A++VA   PF+ VE
Sbjct: 43  GWRKQSAGPNSPTGGGGGGGSGGTRMRDGLVIP--------LVELSAKQVAFHIPFEVVE 94

Query: 96  ERFERIPEPVQRRIVYWSFPRSEREICMYSSFNTGGGAAGGPGD 139
           + +  +PE +Q RI +WSFP +E +I +YS    G       GD
Sbjct: 95  KVYPPVPEQLQLRIAFWSFPENEEDIRLYSCLANGSADEFQRGD 138



 Score = 37.4 bits (85), Expect = 0.088
 Identities = 43/160 (26%), Positives = 65/160 (40%), Gaps = 27/160 (16%)

Query: 887  PDITLLKVSLELGLQVMRM-TLSTLNWRRREM---VRWLVTCATEVGVYALDSIMQTWFT 942
            P   L   + E+GL  + +    + NW  R     V W+   A E+G  AL  +++ W  
Sbjct: 1278 PHRNLHLCAFEIGLYALGLHNFVSPNWLSRTYSSHVSWITGQAMEIGSAALTILVECWDG 1337

Query: 943  LFTPTEATSIVATTVMSNSTIVRLHLDCHQQEKLASSARTLALQCAMKDPQNCALS---- 998
              TP E  S+      +            +   +  +A  LAL C    P   AL+    
Sbjct: 1338 HLTPPEVASLADRASRA------------RDSNMVRAAAELALSCL---PHAHALNPNEI 1382

Query: 999  --ALTLC-EKDHIAFETAYQIVLDAATTGMSYTQ-LFTIA 1034
              AL  C E+D++  E A   V +AA  G  Y + LF +A
Sbjct: 1383 QRALVQCKEQDNLMLEKACMAVEEAAKGGGVYPEVLFEVA 1422


>gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2
           [Homo sapiens]
          Length = 2191

 Score = 67.8 bits (164), Expect = 6e-11
 Identities = 73/222 (32%), Positives = 85/222 (38%), Gaps = 45/222 (20%)

Query: 2   AERGQQPPPAKRLCCRPG---------GGGGGGGSSGGGGGA------------GGGYSS 40
           A  GQ  PP   L  +PG         G   GG     G GA            GGG  +
Sbjct: 108 AAGGQADPPGPPLLSKPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPA 167

Query: 41  ACRPGPRAGGAAAAAACGGGAALGLL--PPGKTQSPESLLDIAARRVAEKWPFQRVEERF 98
           A        G+AA A+ G G   G      G  QSP   +  +A   A   P        
Sbjct: 168 AVPEFNNYYGSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSM----- 222

Query: 99  ERIPEPVQRRIVYWSFPRSE-REICMYSSFNTGGGAAGGPGDDSGGGGGAGGGGGGGSSS 157
               +P+Q    +  +P S+      YS    GGG  GG G   GG GG GGGGG G   
Sbjct: 223 ----DPLQNS--HEGYPNSQCNHYPGYSRPGAGGGGGGG-GGGGGGSGGGGGGGGAG--- 272

Query: 158 SPAATSAAATSAAAAAAAAAAAAAAAAGAGAPSVGAAGAADG 199
                 A    A A AAAAAAAAAAA G G    G + A  G
Sbjct: 273 ------AGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYG 308



 Score = 58.2 bits (139), Expect = 5e-08
 Identities = 57/201 (28%), Positives = 72/201 (35%), Gaps = 21/201 (10%)

Query: 19  GGGGGGGGSSGGGGGAGGGYSSACRPGPRAGGAAAAAACGGG---------AALGLLPPG 69
           GGGGGGGGS GGGGG G G   A      A  AAAAAA GGG         A  G+L   
Sbjct: 254 GGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSP 313

Query: 70  KTQS-----------PESLLDIAARRVAEKWPFQRVEERFERIPEPVQRRIVYWSFPRSE 118
           + Q              SL   AA   A  +     + +      P   +++    P   
Sbjct: 314 RQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMR 373

Query: 119 REICMYSSFNTGGGAAGGPGDDSGGGGGAGGGGGGGSSSSPAATSAAATSAAAAAAAAAA 178
                Y  +++       P         AG   GG  +++          A  AAA+ A 
Sbjct: 374 SYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDM-GAQYAAASPAW 432

Query: 179 AAAAAAGAGAPSVGAAGAADG 199
           AAA      A S G  G   G
Sbjct: 433 AAAQQRSHPAMSPGTPGPTMG 453


>gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1
           [Homo sapiens]
          Length = 2231

 Score = 67.8 bits (164), Expect = 6e-11
 Identities = 73/222 (32%), Positives = 85/222 (38%), Gaps = 45/222 (20%)

Query: 2   AERGQQPPPAKRLCCRPG---------GGGGGGGSSGGGGGA------------GGGYSS 40
           A  GQ  PP   L  +PG         G   GG     G GA            GGG  +
Sbjct: 108 AAGGQADPPGPPLLSKPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPA 167

Query: 41  ACRPGPRAGGAAAAAACGGGAALGLL--PPGKTQSPESLLDIAARRVAEKWPFQRVEERF 98
           A        G+AA A+ G G   G      G  QSP   +  +A   A   P        
Sbjct: 168 AVPEFNNYYGSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSM----- 222

Query: 99  ERIPEPVQRRIVYWSFPRSE-REICMYSSFNTGGGAAGGPGDDSGGGGGAGGGGGGGSSS 157
               +P+Q    +  +P S+      YS    GGG  GG G   GG GG GGGGG G   
Sbjct: 223 ----DPLQNS--HEGYPNSQCNHYPGYSRPGAGGGGGGG-GGGGGGSGGGGGGGGAG--- 272

Query: 158 SPAATSAAATSAAAAAAAAAAAAAAAAGAGAPSVGAAGAADG 199
                 A    A A AAAAAAAAAAA G G    G + A  G
Sbjct: 273 ------AGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYG 308



 Score = 58.2 bits (139), Expect = 5e-08
 Identities = 57/201 (28%), Positives = 72/201 (35%), Gaps = 21/201 (10%)

Query: 19  GGGGGGGGSSGGGGGAGGGYSSACRPGPRAGGAAAAAACGGG---------AALGLLPPG 69
           GGGGGGGGS GGGGG G G   A      A  AAAAAA GGG         A  G+L   
Sbjct: 254 GGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSP 313

Query: 70  KTQS-----------PESLLDIAARRVAEKWPFQRVEERFERIPEPVQRRIVYWSFPRSE 118
           + Q              SL   AA   A  +     + +      P   +++    P   
Sbjct: 314 RQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMR 373

Query: 119 REICMYSSFNTGGGAAGGPGDDSGGGGGAGGGGGGGSSSSPAATSAAATSAAAAAAAAAA 178
                Y  +++       P         AG   GG  +++          A  AAA+ A 
Sbjct: 374 SYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDM-GAQYAAASPAW 432

Query: 179 AAAAAAGAGAPSVGAAGAADG 199
           AAA      A S G  G   G
Sbjct: 433 AAAQQRSHPAMSPGTPGPTMG 453


>gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3
           [Homo sapiens]
          Length = 2178

 Score = 67.8 bits (164), Expect = 6e-11
 Identities = 73/222 (32%), Positives = 85/222 (38%), Gaps = 45/222 (20%)

Query: 2   AERGQQPPPAKRLCCRPG---------GGGGGGGSSGGGGGA------------GGGYSS 40
           A  GQ  PP   L  +PG         G   GG     G GA            GGG  +
Sbjct: 108 AAGGQADPPGPPLLSKPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPA 167

Query: 41  ACRPGPRAGGAAAAAACGGGAALGLL--PPGKTQSPESLLDIAARRVAEKWPFQRVEERF 98
           A        G+AA A+ G G   G      G  QSP   +  +A   A   P        
Sbjct: 168 AVPEFNNYYGSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSM----- 222

Query: 99  ERIPEPVQRRIVYWSFPRSE-REICMYSSFNTGGGAAGGPGDDSGGGGGAGGGGGGGSSS 157
               +P+Q    +  +P S+      YS    GGG  GG G   GG GG GGGGG G   
Sbjct: 223 ----DPLQNS--HEGYPNSQCNHYPGYSRPGAGGGGGGG-GGGGGGSGGGGGGGGAG--- 272

Query: 158 SPAATSAAATSAAAAAAAAAAAAAAAAGAGAPSVGAAGAADG 199
                 A    A A AAAAAAAAAAA G G    G + A  G
Sbjct: 273 ------AGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYG 308



 Score = 58.2 bits (139), Expect = 5e-08
 Identities = 57/201 (28%), Positives = 72/201 (35%), Gaps = 21/201 (10%)

Query: 19  GGGGGGGGSSGGGGGAGGGYSSACRPGPRAGGAAAAAACGGG---------AALGLLPPG 69
           GGGGGGGGS GGGGG G G   A      A  AAAAAA GGG         A  G+L   
Sbjct: 254 GGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSP 313

Query: 70  KTQS-----------PESLLDIAARRVAEKWPFQRVEERFERIPEPVQRRIVYWSFPRSE 118
           + Q              SL   AA   A  +     + +      P   +++    P   
Sbjct: 314 RQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMR 373

Query: 119 REICMYSSFNTGGGAAGGPGDDSGGGGGAGGGGGGGSSSSPAATSAAATSAAAAAAAAAA 178
                Y  +++       P         AG   GG  +++          A  AAA+ A 
Sbjct: 374 SYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDM-GAQYAAASPAW 432

Query: 179 AAAAAAGAGAPSVGAAGAADG 199
           AAA      A S G  G   G
Sbjct: 433 AAAQQRSHPAMSPGTPGPTMG 453


>gi|22748877 basic helix-loop-helix domain containing, class B, 5
           [Homo sapiens]
          Length = 381

 Score = 63.5 bits (153), Expect = 1e-09
 Identities = 55/169 (32%), Positives = 77/169 (45%), Gaps = 12/169 (7%)

Query: 8   PPPAKRLCCRPGGGGGGGGSSGGGGGAGGGYSSACRPGPRAGGAAAAAACGGGAALGLLP 67
           P  A  L   PGGGGGG   SGGGGG G G           GG  + ++   GAAL  L 
Sbjct: 70  PEGAGLLLPPPGGGGGGSAGSGGGGGGGVGVPGLLVGSAGVGGDPSLSSLPAGAAL-CLK 128

Query: 68  PGKTQSPESLLDIAARRVAEKWPFQRVEERFERIPEP--VQRRIVYWSFPRSEREICMYS 125
            G++ S  S   +A     E+ P    + R E +        R    +     +     S
Sbjct: 129 YGESASRGS---VAESSGGEQSPDDDSDGRCELVLRAGVADPRASPGAGGGGAKAAEGCS 185

Query: 126 SFNTGGGAAGGPGDDSGGGGG------AGGGGGGGSSSSPAATSAAATS 168
           + +  GGA+  PG   GGGGG      +GGGGG GS S  +++S++++S
Sbjct: 186 NAHLHGGASVPPGGLGGGGGGGSSSGSSGGGGGSGSGSGGSSSSSSSSS 234



 Score = 40.0 bits (92), Expect = 0.014
 Identities = 27/85 (31%), Positives = 37/85 (43%), Gaps = 2/85 (2%)

Query: 130 GGGAAGGPGDDSGGGGGAGGGGGGGSSSSPAATSAAATSAAAAAAAAAAAAAAAAGAGAP 189
           GGG  G  G   GGGGG G  G    S+      + ++  A AA       +A+ G+ A 
Sbjct: 81  GGGGGGSAGSGGGGGGGVGVPGLLVGSAGVGGDPSLSSLPAGAALCLKYGESASRGSVAE 140

Query: 190 SVGAAGAADGGDETR--LPFRRGIA 212
           S G   + D   + R  L  R G+A
Sbjct: 141 SSGGEQSPDDDSDGRCELVLRAGVA 165



 Score = 38.1 bits (87), Expect = 0.051
 Identities = 49/195 (25%), Positives = 77/195 (39%), Gaps = 23/195 (11%)

Query: 18  PGGGGGG-------------GGSSGGGGGAGGGYSSACRPGPRAGGAAAAAACGGGAALG 64
           PG GGGG             GG+S   GG GGG       G   GG  + +  GG ++  
Sbjct: 171 PGAGGGGAKAAEGCSNAHLHGGASVPPGGLGGGGGGGSSSGSSGGGGGSGSGSGGSSSSS 230

Query: 65  LLPPGKTQSPESL-LDIAARRVAEKWPFQRVEERFERIPEPVQRRIVYWSFPRSEREICM 123
                K++  ++L L+I AR        +R+ +  + + E   R ++ ++   S R++  
Sbjct: 231 SSSSKKSKEQKALRLNINARE------RRRMHDLNDALDE--LRAVIPYAHSPSVRKLSK 282

Query: 124 YSSFNTGGGAAGGPGDDSGGGGGAGGGGGGGSSSSPAATSAAATSAAAAAAAAAAAAAAA 183
            ++                           G + S A+  ++A +AAAAAA   A  A  
Sbjct: 283 IATLLLAKNYILMQAQALEEMRRLVAYLNQGQAISAASLPSSAAAAAAAAALHPALGAYE 342

Query: 184 AGAGAP-SVGAAGAA 197
             AG P S G   AA
Sbjct: 343 QAAGYPFSAGLPPAA 357



 Score = 36.2 bits (82), Expect = 0.20
 Identities = 23/84 (27%), Positives = 33/84 (39%), Gaps = 2/84 (2%)

Query: 122 CMYSSFNTGGGAAGGPGDDSGGGGGAGGGGGGGSSSSPA--ATSAAATSAAAAAAAAAAA 179
           C   +   G G    P    GGG    GGGGGG    P     SA      + ++  A A
Sbjct: 64  CFEPADPEGAGLLLPPPGGGGGGSAGSGGGGGGGVGVPGLLVGSAGVGGDPSLSSLPAGA 123

Query: 180 AAAAAGAGAPSVGAAGAADGGDET 203
           A       + S G+   + GG+++
Sbjct: 124 ALCLKYGESASRGSVAESSGGEQS 147


>gi|109255251 loricrin [Homo sapiens]
          Length = 312

 Score = 63.2 bits (152), Expect = 1e-09
 Identities = 50/187 (26%), Positives = 71/187 (37%), Gaps = 53/187 (28%)

Query: 16  CRPGGGGGGGGSSGGGGG---AGGGYSSACRPGPRAGGAAAAAACGGGAALGLLPPGKTQ 72
           C+  GG   GGSSGGG G   +GGG  S C  G   GG+       GG+  G        
Sbjct: 158 CQSYGGVSSGGSSGGGSGCFSSGGGGGSVC--GYSGGGSGCGGGSSGGSGSGY------- 208

Query: 73  SPESLLDIAARRVAEKWPFQRVEERFERIPEPVQRRIVYWSFPRSEREICMYSSFNTGGG 132
                  +++++V +              P+P                   Y   ++GGG
Sbjct: 209 -------VSSQQVTQT----------SCAPQP------------------SYGGGSSGGG 233

Query: 133 AAGGPGDDSGGGGGAGGGGGGGSSSSPAATSAAATSAAAAAAAAAAAAAAAAGAGAPSVG 192
            +GG G  S GGGG   G GGGSS         +    +   +     ++  G G  SVG
Sbjct: 234 GSGGSGCFSSGGGGGSSGCGGGSS------GIGSGCIISGGGSVCGGGSSGGGGGGSSVG 287

Query: 193 AAGAADG 199
            +G+  G
Sbjct: 288 GSGSGKG 294



 Score = 53.9 bits (128), Expect = 9e-07
 Identities = 32/72 (44%), Positives = 40/72 (55%), Gaps = 9/72 (12%)

Query: 1  MAERGQQPPPAKRLCC--RPGGGGGGGGSSGGG------GGAGGGYSSACRPGPRAGGAA 52
          M+ + +QP P   + C    GGGGGGGGS GGG      GG+GGG SS    G   GG  
Sbjct: 1  MSYQKKQPTPQPPVDCVKTSGGGGGGGGSGGGGCGFFGGGGSGGG-SSGSGCGYSGGGGY 59

Query: 53 AAAACGGGAALG 64
          +   CGGG++ G
Sbjct: 60 SGGGCGGGSSGG 71



 Score = 52.8 bits (125), Expect = 2e-06
 Identities = 58/226 (25%), Positives = 77/226 (34%), Gaps = 63/226 (27%)

Query: 16  CRPGGGG-----GGGGSSGGG------GGAGGGYSSACRPGPRAGGAAAAAACGG---GA 61
           C  G GG     GGGGSSGGG      GG G G  S+   G   GG+   ++ GG   G 
Sbjct: 80  CGGGSGGSVKYSGGGGSSGGGSGCFSSGGGGSGCFSSGGGGSSGGGSGCFSSGGGGSSGG 139

Query: 62  ALGLLPPGKTQSPESLLDIAARRVAEKWPFQRVEERFERIPEPVQRRIVYWSFPRSEREI 121
             G    G                                            F     + 
Sbjct: 140 GSGCFSSGGG-----------------------------------------GFSGQAVQC 158

Query: 122 CMYSSFNTGGGAAGGPGDDSGGGGG------AGGGGGGGSSSSPAATSAAATSAAAAAAA 175
             Y   ++GG + GG G  S GGGG      +GGG G G  SS  + S   +S      +
Sbjct: 159 QSYGGVSSGGSSGGGSGCFSSGGGGGSVCGYSGGGSGCGGGSSGGSGSGYVSSQQVTQTS 218

Query: 176 AAAAAAAAAGA--GAPSVGAAGAADGGDETRLPFRRGIALLESGCV 219
            A   +   G+  G  S G+   + GG         G + + SGC+
Sbjct: 219 CAPQPSYGGGSSGGGGSGGSGCFSSGGGGGSSGCGGGSSGIGSGCI 264



 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 25/72 (34%), Positives = 29/72 (40%), Gaps = 4/72 (5%)

Query: 129 TGGGAAGGPGDDSGGGGGAGGGGGGGSSSSPAATSAAATSAAAAAAAAAAAAAAAAGAGA 188
           T GG  GG G   GG G  GGGG GG SS     S    S     +       ++ G G 
Sbjct: 19  TSGGGGGGGGSGGGGCGFFGGGGSGGGSSG----SGCGYSGGGGYSGGGCGGGSSGGGGG 74

Query: 189 PSVGAAGAADGG 200
             +G  G   GG
Sbjct: 75  GGIGGCGGGSGG 86



 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 27/81 (33%), Positives = 36/81 (44%), Gaps = 5/81 (6%)

Query: 125 SSFNTGGGAAGGPGDDSGG-----GGGAGGGGGGGSSSSPAATSAAATSAAAAAAAAAAA 179
           SS   GGG  GG G  SGG     GGG   GGG G  SS    S   +S    ++   + 
Sbjct: 68  SSGGGGGGGIGGCGGGSGGSVKYSGGGGSSGGGSGCFSSGGGGSGCFSSGGGGSSGGGSG 127

Query: 180 AAAAAGAGAPSVGAAGAADGG 200
             ++ G G+   G+   + GG
Sbjct: 128 CFSSGGGGSSGGGSGCFSSGG 148



 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 30/81 (37%), Positives = 38/81 (46%), Gaps = 8/81 (9%)

Query: 122 CMYSSFNTGGGAAGGP--GDDSGGGGGAGGGGGGGSSSSPAATSAAATSAAAAAAAAAAA 179
           C YS    GGG +GG   G  SGGGGG G GG GG S      S    S   +   +   
Sbjct: 51  CGYSG---GGGYSGGGCGGGSSGGGGGGGIGGCGGGSGGSVKYSGGGGS---SGGGSGCF 104

Query: 180 AAAAAGAGAPSVGAAGAADGG 200
           ++   G+G  S G  G++ GG
Sbjct: 105 SSGGGGSGCFSSGGGGSSGGG 125



 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 27/84 (32%), Positives = 40/84 (47%), Gaps = 9/84 (10%)

Query: 124 YSSFNTGGGAAGGPGDDSGGGGGAGGG-------GGGGSSSSPAATSAAATSAAAAAAAA 176
           YS    GGG++GG G   GG GG GGG        GGG SS   +   ++    +   ++
Sbjct: 59  YSGGGCGGGSSGGGG--GGGIGGCGGGSGGSVKYSGGGGSSGGGSGCFSSGGGGSGCFSS 116

Query: 177 AAAAAAAAGAGAPSVGAAGAADGG 200
               ++  G+G  S G  G++ GG
Sbjct: 117 GGGGSSGGGSGCFSSGGGGSSGGG 140



 Score = 44.3 bits (103), Expect = 7e-04
 Identities = 21/71 (29%), Positives = 32/71 (45%)

Query: 129 TGGGAAGGPGDDSGGGGGAGGGGGGGSSSSPAATSAAATSAAAAAAAAAAAAAAAAGAGA 188
           +GGG++G     SGGGG +GGG GGGSS              +  +   +    ++G G+
Sbjct: 42  SGGGSSGSGCGYSGGGGYSGGGCGGGSSGGGGGGGIGGCGGGSGGSVKYSGGGGSSGGGS 101

Query: 189 PSVGAAGAADG 199
               + G   G
Sbjct: 102 GCFSSGGGGSG 112



 Score = 42.4 bits (98), Expect = 0.003
 Identities = 19/42 (45%), Positives = 25/42 (59%)

Query: 20  GGGGGGGSSGGGGGAGGGYSSACRPGPRAGGAAAAAACGGGA 61
           GGGGGGG  G GGG+GG    +   G   GG+   ++ GGG+
Sbjct: 70  GGGGGGGIGGCGGGSGGSVKYSGGGGSSGGGSGCFSSGGGGS 111



 Score = 42.0 bits (97), Expect = 0.004
 Identities = 23/50 (46%), Positives = 25/50 (50%), Gaps = 10/50 (20%)

Query: 19 GGGGGGGGSSG-------GGGGAGGGYSSACRPGPRAGGAAAAAACGGGA 61
          GGGG GGGSSG       GGG +GGG       G   GG      CGGG+
Sbjct: 38 GGGGSGGGSSGSGCGYSGGGGYSGGGCGGGSSGG---GGGGGIGGCGGGS 84



 Score = 41.2 bits (95), Expect = 0.006
 Identities = 22/67 (32%), Positives = 29/67 (43%), Gaps = 5/67 (7%)

Query: 15  CCRPGGGGGGGGSSGGGGGAGGGY-----SSACRPGPRAGGAAAAAACGGGAALGLLPPG 69
           C   GGGGG  G  GG  G G G       S C  G   GG   ++  G G+  G+    
Sbjct: 240 CFSSGGGGGSSGCGGGSSGIGSGCIISGGGSVCGGGSSGGGGGGSSVGGSGSGKGVPICH 299

Query: 70  KTQSPES 76
           +TQ  ++
Sbjct: 300 QTQQKQA 306



 Score = 40.0 bits (92), Expect = 0.014
 Identities = 19/48 (39%), Positives = 23/48 (47%)

Query: 15  CCRPGGGGGGGGSSGGGGGAGGGYSSACRPGPRAGGAAAAAACGGGAA 62
           C     GGGGGG  GG GG  GG       G  +GG +   + GGG +
Sbjct: 64  CGGGSSGGGGGGGIGGCGGGSGGSVKYSGGGGSSGGGSGCFSSGGGGS 111



 Score = 38.5 bits (88), Expect = 0.039
 Identities = 23/53 (43%), Positives = 27/53 (50%), Gaps = 7/53 (13%)

Query: 19  GGGGGGGGSSGGGGG-----AGGGYSSACRPG--PRAGGAAAAAACGGGAALG 64
           GGGGGG G  GGG G     +GGG SS    G     GG +   + GGG + G
Sbjct: 71  GGGGGGIGGCGGGSGGSVKYSGGGGSSGGGSGCFSSGGGGSGCFSSGGGGSSG 123



 Score = 38.1 bits (87), Expect = 0.051
 Identities = 22/52 (42%), Positives = 26/52 (50%), Gaps = 4/52 (7%)

Query: 15  CCRPGGGGGGGGSSGGG--GGAGGGYSSACRPGPRAGGAAAAAACGGGAALG 64
           C   GGGG  GG  GGG  GG GGG    C  G  +GG+   +  GG +  G
Sbjct: 51  CGYSGGGGYSGGGCGGGSSGGGGGGGIGGC--GGGSGGSVKYSGGGGSSGGG 100



 Score = 37.4 bits (85), Expect = 0.088
 Identities = 21/74 (28%), Positives = 25/74 (33%), Gaps = 3/74 (4%)

Query: 130 GGGAAGGPGDDSGGGGGAGGGGGGGSSSSPAATSAAATSAAAAAAAAAAAAAAAAGAGAP 189
           GG   GG G   GGG G G  G G   S     S       ++            G    
Sbjct: 27  GGSGGGGCGFFGGGGSGGGSSGSGCGYSGGGGYSGGGCGGGSSGGGGGGGIGGCGGGSGG 86

Query: 190 SV---GAAGAADGG 200
           SV   G  G++ GG
Sbjct: 87  SVKYSGGGGSSGGG 100



 Score = 34.7 bits (78), Expect = 0.57
 Identities = 14/31 (45%), Positives = 17/31 (54%)

Query: 129 TGGGAAGGPGDDSGGGGGAGGGGGGGSSSSP 159
           +GGG+  G G   GGGGG+  GG G     P
Sbjct: 266 SGGGSVCGGGSSGGGGGGSSVGGSGSGKGVP 296



 Score = 34.3 bits (77), Expect = 0.74
 Identities = 19/74 (25%), Positives = 26/74 (35%), Gaps = 2/74 (2%)

Query: 127 FNTGGGAAGGPGDDSGGGGGAGGGGGGGSSSSPAATSAAATSAAAAAAAAAAAAAAAAGA 186
           F  GGG+ GG      G  G GG  GGG      ++              +  +   +G 
Sbjct: 36  FFGGGGSGGGSSGSGCGYSGGGGYSGGGCGG--GSSGGGGGGGIGGCGGGSGGSVKYSGG 93

Query: 187 GAPSVGAAGAADGG 200
           G  S G +G    G
Sbjct: 94  GGSSGGGSGCFSSG 107



 Score = 32.7 bits (73), Expect = 2.2
 Identities = 14/24 (58%), Positives = 16/24 (66%)

Query: 14  LCCRPGGGGGGGGSSGGGGGAGGG 37
           +C     GGGGGGSS GG G+G G
Sbjct: 271 VCGGGSSGGGGGGSSVGGSGSGKG 294


>gi|12707580 paired-like homeobox 2b [Homo sapiens]
          Length = 314

 Score = 62.0 bits (149), Expect = 3e-09
 Identities = 36/69 (52%), Positives = 39/69 (56%), Gaps = 1/69 (1%)

Query: 126 SFNTGGGAAGGPGDDSGGGGGAGGGGGGGSSSSPAATSAAATSAAAAAAAAAAAAAAAAG 185
           S    GG  GGP   +G  G AG GG GG      A +AAA +AAAAAAAAAAAA   A 
Sbjct: 207 SCGANGGGGGGPSP-AGAPGAAGPGGPGGEPGKGGAAAAAAAAAAAAAAAAAAAAGGLAA 265

Query: 186 AGAPSVGAA 194
           AG P  G A
Sbjct: 266 AGGPGQGWA 274



 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 37/84 (44%), Positives = 41/84 (48%), Gaps = 11/84 (13%)

Query: 128 NTGGGAAGGPGDDSGGGGGAGGGGGGGSSSSPAATSAAA-----------TSAAAAAAAA 176
           +T   + GGPG +       G  GGGG   SPA    AA             AAAAAAAA
Sbjct: 189 STDPDSTGGPGPNPNPTPSCGANGGGGGGPSPAGAPGAAGPGGPGGEPGKGGAAAAAAAA 248

Query: 177 AAAAAAAAGAGAPSVGAAGAADGG 200
           AAAAAAAA A A  + AAG    G
Sbjct: 249 AAAAAAAAAAAAGGLAAAGGPGQG 272



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 33/81 (40%), Positives = 39/81 (48%), Gaps = 13/81 (16%)

Query: 5   GQQPPPAKRLCCRPGGGGGGG-------GSSGGGGGAG----GGYSSACRPGPRAGGAAA 53
           G  P P     C   GGGGGG       G++G GG  G    GG ++A      A  AAA
Sbjct: 197 GPGPNPNPTPSCGANGGGGGGPSPAGAPGAAGPGGPGGEPGKGGAAAAAAAAAAAAAAAA 256

Query: 54  AAACGGGAALGLLPPGKTQSP 74
           AAA GG AA G   PG+  +P
Sbjct: 257 AAAAGGLAAAG--GPGQGWAP 275



 Score = 42.0 bits (97), Expect = 0.004
 Identities = 32/72 (44%), Positives = 37/72 (51%), Gaps = 11/72 (15%)

Query: 128 NTGGGA----AGGPG--DDSGGGGGAGGGGGGGSSSSPAATSAAATSAAAAAAAAAAAAA 181
           N GGG     AG PG     G GG  G GG   ++++ AA +AA    AAAAAA   AAA
Sbjct: 211 NGGGGGGPSPAGAPGAAGPGGPGGEPGKGGAAAAAAAAAAAAAA----AAAAAAGGLAAA 266

Query: 182 AAAGAG-APSVG 192
              G G AP  G
Sbjct: 267 GGPGQGWAPGPG 278


>gi|195972866 keratin 10 [Homo sapiens]
          Length = 584

 Score = 58.2 bits (139), Expect = 5e-08
 Identities = 45/149 (30%), Positives = 55/149 (36%), Gaps = 49/149 (32%)

Query: 19  GGGGGGGGSSGGGGGAGGGYSSACRPGPRAGGAAAAAACGGGAALGLLPPGKTQSPESLL 78
           GGG  GGGSSGGG G G G SS    G   GG++   + GGG   G    G   S     
Sbjct: 474 GGGSSGGGSSGGGHGGGHGGSSG---GGYGGGSSGGGSSGGGYGGGSSSGGHGGSSSG-- 528

Query: 79  DIAARRVAEKWPFQRVEERFERIPEPVQRRIVYWSFPRSEREICMYSSFNTGGGAAGGPG 138
                                                        Y   ++GGG  G  G
Sbjct: 529 --------------------------------------------GYGGGSSGGGGGGYGG 544

Query: 139 DDSGGGGGAGGGGGGGSSSSPAATSAAAT 167
             SGGG  +GGG GGGSSS    +S++ +
Sbjct: 545 GSSGGGSSSGGGYGGGSSSGGHKSSSSGS 573



 Score = 48.5 bits (114), Expect = 4e-05
 Identities = 29/96 (30%), Positives = 38/96 (39%), Gaps = 11/96 (11%)

Query: 116 RSEREICMYSSFNTGGGAAGGPGDDSG-----------GGGGAGGGGGGGSSSSPAATSA 164
           R E EI  Y S   G G++GG G   G           GGG +GGG GGG   S      
Sbjct: 441 RLENEIQTYRSLLEGEGSSGGGGRGGGSFGGGYGGGSSGGGSSGGGHGGGHGGSSGGGYG 500

Query: 165 AATSAAAAAAAAAAAAAAAAGAGAPSVGAAGAADGG 200
             +S   ++       +++ G G  S G  G    G
Sbjct: 501 GGSSGGGSSGGGYGGGSSSGGHGGSSSGGYGGGSSG 536



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 21/71 (29%), Positives = 32/71 (45%)

Query: 130 GGGAAGGPGDDSGGGGGAGGGGGGGSSSSPAATSAAATSAAAAAAAAAAAAAAAAGAGAP 189
           GGG++GG     G GGG GG  GGG     +   ++       +++     +++ G G  
Sbjct: 474 GGGSSGGGSSGGGHGGGHGGSSGGGYGGGSSGGGSSGGGYGGGSSSGGHGGSSSGGYGGG 533

Query: 190 SVGAAGAADGG 200
           S G  G   GG
Sbjct: 534 SSGGGGGGYGG 544



 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 27/87 (31%), Positives = 41/87 (47%), Gaps = 11/87 (12%)

Query: 128 NTGGGAAGGPGDDSGGG---GGAGGG------GGGGSSSSPAATSAAATSAAAAAAAAAA 178
           ++GGG  GG G  SGGG   G +GGG      GGG SS     +S+      ++      
Sbjct: 482 SSGGGHGGGHGGSSGGGYGGGSSGGGSSGGGYGGGSSSGGHGGSSSGGYGGGSSGGGGGG 541

Query: 179 AAAAAAGAGAPSVG--AAGAADGGDET 203
               ++G G+ S G    G++ GG ++
Sbjct: 542 YGGGSSGGGSSSGGGYGGGSSSGGHKS 568



 Score = 43.5 bits (101), Expect = 0.001
 Identities = 43/154 (27%), Positives = 50/154 (32%), Gaps = 47/154 (30%)

Query: 17  RPGGGGGGGGSSGGGG-----------GAGGGYSSACRPGPR-----AGGAAAAAACGGG 60
           R GGGGGGGG  GGGG             GGG+SS    G       +GG     + GG 
Sbjct: 15  RSGGGGGGGGCGGGGGVSSLRISSSKGSLGGGFSSGGFSGGSFSRGSSGGGCFGGSSGGY 74

Query: 61  AALGLLPPGKTQSPESLLDIAARRVAEKWPFQRVEERFERIPEPVQRRIVYWSFPRSERE 120
             LG    G  +                                        SF      
Sbjct: 75  GGLGGFGGGSFRGSYGSSSFGGSYGG--------------------------SFGGGS-- 106

Query: 121 ICMYSSFNTGGGAAGGPGDDSGGGGGAGGGGGGG 154
              +   + GGG+ GG G   GG GG  GGG GG
Sbjct: 107 ---FGGGSFGGGSFGGGGFGGGGFGGGFGGGFGG 137



 Score = 42.0 bits (97), Expect = 0.004
 Identities = 20/77 (25%), Positives = 32/77 (41%)

Query: 124 YSSFNTGGGAAGGPGDDSGGGGGAGGGGGGGSSSSPAATSAAATSAAAAAAAAAAAAAAA 183
           Y   ++GGG++GG      GG   GG GGG S    +       S++     +++     
Sbjct: 473 YGGGSSGGGSSGGGHGGGHGGSSGGGYGGGSSGGGSSGGGYGGGSSSGGHGGSSSGGYGG 532

Query: 184 AGAGAPSVGAAGAADGG 200
             +G    G  G + GG
Sbjct: 533 GSSGGGGGGYGGGSSGG 549



 Score = 41.6 bits (96), Expect = 0.005
 Identities = 22/62 (35%), Positives = 34/62 (54%), Gaps = 2/62 (3%)

Query: 125 SSFNTGGGAAGGPGDDSGGGGGAGGGGG--GGSSSSPAATSAAATSAAAAAAAAAAAAAA 182
           SS   GG ++GG G  S GGGG G GGG  GG SSS       ++S    ++++ +   +
Sbjct: 518 SSGGHGGSSSGGYGGGSSGGGGGGYGGGSSGGGSSSGGGYGGGSSSGGHKSSSSGSVGES 577

Query: 183 AA 184
           ++
Sbjct: 578 SS 579



 Score = 40.8 bits (94), Expect = 0.008
 Identities = 23/48 (47%), Positives = 27/48 (56%), Gaps = 2/48 (4%)

Query: 19  GGGGGGGGSSGG--GGGAGGGYSSACRPGPRAGGAAAAAACGGGAALG 64
           GGGG GGGS GG  GGG+ GG SS    G   GG++     GG +  G
Sbjct: 460 GGGGRGGGSFGGGYGGGSSGGGSSGGGHGGGHGGSSGGGYGGGSSGGG 507



 Score = 40.4 bits (93), Expect = 0.010
 Identities = 21/72 (29%), Positives = 30/72 (41%), Gaps = 1/72 (1%)

Query: 130 GGGAAGGP-GDDSGGGGGAGGGGGGGSSSSPAATSAAATSAAAAAAAAAAAAAAAAGAGA 188
           GGG  GG  G  S GGG  GG GG         +S   +S       +++     + +G 
Sbjct: 470 GGGYGGGSSGGGSSGGGHGGGHGGSSGGGYGGGSSGGGSSGGGYGGGSSSGGHGGSSSGG 529

Query: 189 PSVGAAGAADGG 200
              G++G   GG
Sbjct: 530 YGGGSSGGGGGG 541



 Score = 40.4 bits (93), Expect = 0.010
 Identities = 21/82 (25%), Positives = 35/82 (42%), Gaps = 3/82 (3%)

Query: 124 YSSFNTGGGAAGGP---GDDSGGGGGAGGGGGGGSSSSPAATSAAATSAAAAAAAAAAAA 180
           Y   ++GGG++GG    G  SGG GG+  GG GG SS          S+   +++     
Sbjct: 499 YGGGSSGGGSSGGGYGGGSSSGGHGGSSSGGYGGGSSGGGGGGYGGGSSGGGSSSGGGYG 558

Query: 181 AAAAGAGAPSVGAAGAADGGDE 202
             ++  G  S  +    +   +
Sbjct: 559 GGSSSGGHKSSSSGSVGESSSK 580



 Score = 38.1 bits (87), Expect = 0.051
 Identities = 20/61 (32%), Positives = 30/61 (49%), Gaps = 1/61 (1%)

Query: 141 SGGGGGAGG-GGGGGSSSSPAATSAAATSAAAAAAAAAAAAAAAAGAGAPSVGAAGAADG 199
           SGGGGG GG GGGGG SS   ++S  +     ++   +  + +   +G    G +    G
Sbjct: 16  SGGGGGGGGCGGGGGVSSLRISSSKGSLGGGFSSGGFSGGSFSRGSSGGGCFGGSSGGYG 75

Query: 200 G 200
           G
Sbjct: 76  G 76



 Score = 38.1 bits (87), Expect = 0.051
 Identities = 23/77 (29%), Positives = 31/77 (40%)

Query: 124 YSSFNTGGGAAGGPGDDSGGGGGAGGGGGGGSSSSPAATSAAATSAAAAAAAAAAAAAAA 183
           +S  ++GGG  GG     GG GG GGG   GS  S +   +   S    +    +    +
Sbjct: 57  FSRGSSGGGCFGGSSGGYGGLGGFGGGSFRGSYGSSSFGGSYGGSFGGGSFGGGSFGGGS 116

Query: 184 AGAGAPSVGAAGAADGG 200
            G G    G  G   GG
Sbjct: 117 FGGGGFGGGGFGGGFGG 133



 Score = 34.7 bits (78), Expect = 0.57
 Identities = 22/61 (36%), Positives = 27/61 (44%), Gaps = 8/61 (13%)

Query: 19  GGGGGGGGSSGGGGGAGGGYSSACRPGPRAGGAAAAAACGGGAALGLLPPGKTQSPESLL 78
           GGG  GGGS GGG   GGG+          GG       G G   GLL   +  + ++L 
Sbjct: 103 GGGSFGGGSFGGGSFGGGGFG--------GGGFGGGFGGGFGGDGGLLSGNEKVTMQNLN 154

Query: 79  D 79
           D
Sbjct: 155 D 155



 Score = 34.7 bits (78), Expect = 0.57
 Identities = 17/41 (41%), Positives = 20/41 (48%), Gaps = 5/41 (12%)

Query: 20  GGGGGGGSSGGGGGAGGGYSSACRPGPRAGGAAAAAACGGG 60
           G G  GG   GGG  GGGY      G  +GG ++    GGG
Sbjct: 455 GEGSSGGGGRGGGSFGGGYG-----GGSSGGGSSGGGHGGG 490



 Score = 34.3 bits (77), Expect = 0.74
 Identities = 19/44 (43%), Positives = 21/44 (47%), Gaps = 3/44 (6%)

Query: 19  GGGGGGGGSSGG---GGGAGGGYSSACRPGPRAGGAAAAAACGG 59
           G G  GGG  GG   GGG GGG S     G   GG    ++ GG
Sbjct: 455 GEGSSGGGGRGGGSFGGGYGGGSSGGGSSGGGHGGGHGGSSGGG 498



 Score = 33.1 bits (74), Expect = 1.7
 Identities = 19/55 (34%), Positives = 23/55 (41%), Gaps = 10/55 (18%)

Query: 16  CRPGGGGGGGGSSGGGGGA----------GGGYSSACRPGPRAGGAAAAAACGGG 60
           C  G  GG GG  G GGG+          GG Y  +   G   GG+    + GGG
Sbjct: 66  CFGGSSGGYGGLGGFGGGSFRGSYGSSSFGGSYGGSFGGGSFGGGSFGGGSFGGG 120



 Score = 32.3 bits (72), Expect = 2.8
 Identities = 15/60 (25%), Positives = 26/60 (43%)

Query: 141 SGGGGGAGGGGGGGSSSSPAATSAAATSAAAAAAAAAAAAAAAAGAGAPSVGAAGAADGG 200
           S  GGG GGGG GG     +   +++  +     ++   +  +   G+   G  G + GG
Sbjct: 14  SRSGGGGGGGGCGGGGGVSSLRISSSKGSLGGGFSSGGFSGGSFSRGSSGGGCFGGSSGG 73



 Score = 32.0 bits (71), Expect = 3.7
 Identities = 22/90 (24%), Positives = 31/90 (34%), Gaps = 13/90 (14%)

Query: 124 YSSFNTGGGAAGGPGDDSGG-------------GGGAGGGGGGGSSSSPAATSAAATSAA 170
           YSS  +GGG  GG     GG             GGG   GG  G S S  ++       +
Sbjct: 11  YSSSRSGGGGGGGGCGGGGGVSSLRISSSKGSLGGGFSSGGFSGGSFSRGSSGGGCFGGS 70

Query: 171 AAAAAAAAAAAAAAGAGAPSVGAAGAADGG 200
           +            +  G+    + G + GG
Sbjct: 71  SGGYGGLGGFGGGSFRGSYGSSSFGGSYGG 100



 Score = 32.0 bits (71), Expect = 3.7
 Identities = 17/41 (41%), Positives = 21/41 (51%), Gaps = 1/41 (2%)

Query: 19  GGGGGG-GGSSGGGGGAGGGYSSACRPGPRAGGAAAAAACG 58
           G GGG  GG S  GGG GGG SS       +G    +++ G
Sbjct: 541 GYGGGSSGGGSSSGGGYGGGSSSGGHKSSSSGSVGESSSKG 581


>gi|110347449 POU domain, class 4, transcription factor 1 [Homo
           sapiens]
          Length = 419

 Score = 57.0 bits (136), Expect = 1e-07
 Identities = 44/111 (39%), Positives = 45/111 (40%), Gaps = 43/111 (38%)

Query: 130 GGGAAGGPGDDSGGGGGAGGGGGGGSS---------------------------SSPAA- 161
           G G  GGPG   G GGG GGGGGGG                             S PAA 
Sbjct: 146 GPGGGGGPGGGGGPGGGPGGGGGGGPGGGGGGPGGGLLGGSAHPHPHMHSLGHLSHPAAA 205

Query: 162 ---------------TSAAATSAAAAAAAAAAAAAAAAGAGAPSVGAAGAA 197
                           +AA   AAAAAAAAAA   AAA A A  VGAAG A
Sbjct: 206 AAMNMPSGLPHPGLVAAAAHHGAAAAAAAAAAGQVAAASAAAAVVGAAGLA 256



 Score = 55.1 bits (131), Expect = 4e-07
 Identities = 42/113 (37%), Positives = 47/113 (41%), Gaps = 40/113 (35%)

Query: 130 GGGAAGGPGDDSGGGGGAGGGGGG-------------------GSSSSPAATSA------ 164
           GGG  GGPG   GGGGG GGGGGG                   G  S PAA +A      
Sbjct: 156 GGGPGGGPG--GGGGGGPGGGGGGPGGGLLGGSAHPHPHMHSLGHLSHPAAAAAMNMPSG 213

Query: 165 -------------AATSAAAAAAAAAAAAAAAAGAGAPSVGAAGAADGGDETR 204
                         A +AAAAAAA   AAA+AA A   + G A   D   + R
Sbjct: 214 LPHPGLVAAAAHHGAAAAAAAAAAGQVAAASAAAAVVGAAGLASICDSDTDPR 266



 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 49/178 (27%), Positives = 60/178 (33%), Gaps = 63/178 (35%)

Query: 19  GGGG-----GGGGSSGGGGGAGGGYSSACRPGPRAGGAAAAAACGGGAALGLLPPGKTQS 73
           GGGG     GGGG  GGGGG GG        GP  GG       GGG   GLL       
Sbjct: 139 GGGGAHDGPGGGGGPGGGGGPGG--------GPGGGGGGGPGGGGGGPGGGLLGGSAH-- 188

Query: 74  PESLLDIAARRVAEKWPFQRVEERFERIPEPVQRRIVYWSFPRSEREICMYSSFNTGGGA 133
                                       P P    + + S P +   + M S     G  
Sbjct: 189 ----------------------------PHPHMHSLGHLSHPAAAAAMNMPSGLPHPGLV 220

Query: 134 AGGPGDDSGGGGGAGGGGGGGSSSSPAATSAAATSAAAAAAAAAAAAAAAAGAGAPSV 191
           A                    +++   A +AAA +AA   AAA+AAAA    AG  S+
Sbjct: 221 A--------------------AAAHHGAAAAAAAAAAGQVAAASAAAAVVGAAGLASI 258



 Score = 40.8 bits (94), Expect = 0.008
 Identities = 19/35 (54%), Positives = 20/35 (57%)

Query: 18  PGGGGGGGGSSGGGGGAGGGYSSACRPGPRAGGAA 52
           PGGGGG GG  GGGGG G G       G   GG+A
Sbjct: 153 PGGGGGPGGGPGGGGGGGPGGGGGGPGGGLLGGSA 187



 Score = 40.0 bits (92), Expect = 0.014
 Identities = 23/56 (41%), Positives = 25/56 (44%), Gaps = 4/56 (7%)

Query: 18  PGGGGGGGGSSGGGGGAGGGYSSACRPGPRAGG----AAAAAACGGGAALGLLPPG 69
           PGGGGGGG   GGGG  GG    +  P P        +  AAA       GL  PG
Sbjct: 163 PGGGGGGGPGGGGGGPGGGLLGGSAHPHPHMHSLGHLSHPAAAAAMNMPSGLPHPG 218


>gi|109452587 family with sequence similarity 98, member B isoform 1
           [Homo sapiens]
          Length = 433

 Score = 56.2 bits (134), Expect = 2e-07
 Identities = 47/150 (31%), Positives = 50/150 (33%), Gaps = 44/150 (29%)

Query: 6   QQPPPAKRLCCRPGGGGGGGGSSGGGGGAGGGYSSACRPGPRAGGAAAAAACGGGAALGL 65
           + PP  KR     GGG GG G  GGGGG GGG     R G   GG       GGG   G 
Sbjct: 321 EMPPWQKRQ--EGGGGRGGWGGGGGGGGRGGGGGGGGRGGWGGGGGGWGGGGGGGGGWGG 378

Query: 66  LPPGKTQSPESLLDIAARRVAEKWPFQRVEERFERIPEPVQRRIVYWSFPRSEREICMYS 125
              G     +   D   R                                          
Sbjct: 379 GGGGGRGGFQGRGDYGGR-----------------------------------------G 397

Query: 126 SFNTGGGAAG-GPGDDSGGGGGAGGGGGGG 154
            +   GG  G G GD  GGGGG GGGGGGG
Sbjct: 398 GYGGRGGYGGRGYGDPYGGGGGGGGGGGGG 427



 Score = 40.8 bits (94), Expect = 0.008
 Identities = 24/70 (34%), Positives = 24/70 (34%), Gaps = 5/70 (7%)

Query: 131 GGAAGGPGDDSGGGGGAGGGGGGGSSSSPAATSAAATSAAAAAAAAAAAAAAAAGAGAPS 190
           GG  GG G   GGGGG GGGGGGG                              G G P 
Sbjct: 360 GGGGGGWGGGGGGGGGWGGGGGGGRGG-----FQGRGDYGGRGGYGGRGGYGGRGYGDPY 414

Query: 191 VGAAGAADGG 200
            G  G   GG
Sbjct: 415 GGGGGGGGGG 424



 Score = 40.0 bits (92), Expect = 0.014
 Identities = 21/58 (36%), Positives = 24/58 (41%)

Query: 7   QPPPAKRLCCRPGGGGGGGGSSGGGGGAGGGYSSACRPGPRAGGAAAAAACGGGAALG 64
           +PPP +    +    GGGG    GGGG GGG       G R G        GGG   G
Sbjct: 316 EPPPPEMPPWQKRQEGGGGRGGWGGGGGGGGRGGGGGGGGRGGWGGGGGGWGGGGGGG 373



 Score = 35.8 bits (81), Expect = 0.25
 Identities = 15/24 (62%), Positives = 15/24 (62%)

Query: 130 GGGAAGGPGDDSGGGGGAGGGGGG 153
           GG   G P    GGGGG GGGGGG
Sbjct: 406 GGRGYGDPYGGGGGGGGGGGGGGG 429



 Score = 35.8 bits (81), Expect = 0.25
 Identities = 16/21 (76%), Positives = 16/21 (76%), Gaps = 3/21 (14%)

Query: 18  PGGGGGGGGSSGGGGGAGGGY 38
           P GGGGGGG   GGGG GGGY
Sbjct: 413 PYGGGGGGG---GGGGGGGGY 430



 Score = 30.8 bits (68), Expect = 8.2
 Identities = 17/63 (26%), Positives = 17/63 (26%)

Query: 138 GDDSGGGGGAGGGGGGGSSSSPAATSAAATSAAAAAAAAAAAAAAAAGAGAPSVGAAGAA 197
           G   GG GG GGGGG G                              G G    G  G  
Sbjct: 332 GGGRGGWGGGGGGGGRGGGGGGGGRGGWGGGGGGWGGGGGGGGGWGGGGGGGRGGFQGRG 391

Query: 198 DGG 200
           D G
Sbjct: 392 DYG 394


>gi|49574532 glycogen synthase kinase 3 alpha [Homo sapiens]
          Length = 483

 Score = 54.7 bits (130), Expect = 5e-07
 Identities = 31/87 (35%), Positives = 39/87 (44%), Gaps = 13/87 (14%)

Query: 130 GGGAAGGPGD----------DSGGGGGAGGGGGGGSSSSPAATSAAATSAAAAAAAAAAA 179
           GG + GGPG           + GGGGG GGGG GGS+S P  T       A+  A     
Sbjct: 4   GGPSGGGPGGSGRARTSSFAEPGGGGGGGGGGPGGSASGPGGTGG---GKASVGAMGGGV 60

Query: 180 AAAAAGAGAPSVGAAGAADGGDETRLP 206
            A+++G G    G  G+   G  T  P
Sbjct: 61  GASSSGGGPGGSGGGGSGGPGAGTSFP 87



 Score = 45.1 bits (105), Expect = 4e-04
 Identities = 25/60 (41%), Positives = 29/60 (48%), Gaps = 9/60 (15%)

Query: 19 GGGGGGGGSSGGGGGAGGGYSS---------ACRPGPRAGGAAAAAACGGGAALGLLPPG 69
          GGGGG GGS+ G GG GGG +S         A   G   GG+    + G GA     PPG
Sbjct: 31 GGGGGPGGSASGPGGTGGGKASVGAMGGGVGASSSGGGPGGSGGGGSGGPGAGTSFPPPG 90



 Score = 43.9 bits (102), Expect = 0.001
 Identities = 24/52 (46%), Positives = 25/52 (48%), Gaps = 10/52 (19%)

Query: 19 GGGGGGGG----------SSGGGGGAGGGYSSACRPGPRAGGAAAAAACGGG 60
          GGG GG G            GGGGG GG   SA  PG   GG A+  A GGG
Sbjct: 8  GGGPGGSGRARTSSFAEPGGGGGGGGGGPGGSASGPGGTGGGKASVGAMGGG 59



 Score = 42.0 bits (97), Expect = 0.004
 Identities = 22/70 (31%), Positives = 29/70 (41%), Gaps = 4/70 (5%)

Query: 125 SSFNTGGGAAGGPGDDSGGGGGAGGGGGGGSSSSPAATSAAATSAAAAAAAAAAAAAAAA 184
           SSF   GG  GG G   GG     GG GGG     A+  A      A+++      +   
Sbjct: 20  SSFAEPGGGGGGGGGGPGGSASGPGGTGGGK----ASVGAMGGGVGASSSGGGPGGSGGG 75

Query: 185 GAGAPSVGAA 194
           G+G P  G +
Sbjct: 76  GSGGPGAGTS 85



 Score = 41.6 bits (96), Expect = 0.005
 Identities = 23/77 (29%), Positives = 30/77 (38%), Gaps = 12/77 (15%)

Query: 136 GPGDDSGGGGGA------------GGGGGGGSSSSPAATSAAATSAAAAAAAAAAAAAAA 183
           G G   GG GG+            GGGGGGG     +A+    T    A+  A      A
Sbjct: 3   GGGPSGGGPGGSGRARTSSFAEPGGGGGGGGGGPGGSASGPGGTGGGKASVGAMGGGVGA 62

Query: 184 AGAGAPSVGAAGAADGG 200
           + +G    G+ G   GG
Sbjct: 63  SSSGGGPGGSGGGGSGG 79



 Score = 38.1 bits (87), Expect = 0.051
 Identities = 21/74 (28%), Positives = 27/74 (36%), Gaps = 1/74 (1%)

Query: 130 GGGAAGGPGDDSGGGGGAGGGGGGGSSSSPAATSAAATSAAAAAAAAAAAAAAAAGAGAP 189
           GGG  GGPG  S  G G  GGG     +      A+++      +    +    AG   P
Sbjct: 29  GGGGGGGPGG-SASGPGGTGGGKASVGAMGGGVGASSSGGGPGGSGGGGSGGPGAGTSFP 87

Query: 190 SVGAAGAADGGDET 203
             G     D G  T
Sbjct: 88  PPGVKLGRDSGKVT 101



 Score = 36.2 bits (82), Expect = 0.20
 Identities = 34/153 (22%), Positives = 43/153 (28%), Gaps = 50/153 (32%)

Query: 24  GGGSSGGGGGAGGGYSSACRPGPRAGGAAAAAACGGGAALGLLPPGKTQSPESLLDIAAR 83
           GGG SGGG G  G   ++    P  GG       GG A+     PG T   ++ +     
Sbjct: 3   GGGPSGGGPGGSGRARTSSFAEPGGGGGGGGGGPGGSAS----GPGGTGGGKASV----- 53

Query: 84  RVAEKWPFQRVEERFERIPEPVQRRIVYWSFPRSEREICMYSSFNTGGGAAGGPGDDSGG 143
                                                     +   G GA+   G   G 
Sbjct: 54  -----------------------------------------GAMGGGVGASSSGGGPGGS 72

Query: 144 GGGAGGGGGGGSSSSPAATSAAATSAAAAAAAA 176
           GGG  GG G G+S  P        S       A
Sbjct: 73  GGGGSGGPGAGTSFPPPGVKLGRDSGKVTTVVA 105



 Score = 34.7 bits (78), Expect = 0.57
 Identities = 20/63 (31%), Positives = 24/63 (38%), Gaps = 3/63 (4%)

Query: 144 GGGAGGGGGGGSS---SSPAATSAAATSAAAAAAAAAAAAAAAAGAGAPSVGAAGAADGG 200
           GGG  GGG GGS    +S  A               +A+     G G  SVGA G   G 
Sbjct: 3   GGGPSGGGPGGSGRARTSSFAEPGGGGGGGGGGPGGSASGPGGTGGGKASVGAMGGGVGA 62

Query: 201 DET 203
             +
Sbjct: 63  SSS 65



 Score = 32.7 bits (73), Expect = 2.2
 Identities = 15/29 (51%), Positives = 17/29 (58%)

Query: 21 GGGGGGSSGGGGGAGGGYSSACRPGPRAG 49
          GGG GGS GGG G  G  +S   PG + G
Sbjct: 66 GGGPGGSGGGGSGGPGAGTSFPPPGVKLG 94


>gi|89257348 homeo box HB9 [Homo sapiens]
          Length = 401

 Score = 53.9 bits (128), Expect = 9e-07
 Identities = 32/72 (44%), Positives = 36/72 (50%), Gaps = 6/72 (8%)

Query: 4   RGQQPPPAKRLCC------RPGGGGGGGGSSGGGGGAGGGYSSACRPGPRAGGAAAAAAC 57
           R + P P + L        +PG  G GGG  G GGG GG +  A      A  AAAAAA 
Sbjct: 74  RAESPSPPRLLAAHCALLPKPGFLGAGGGGGGTGGGHGGPHHHAHPGAAAAAAAAAAAAA 133

Query: 58  GGGAALGLLPPG 69
            GG ALGL P G
Sbjct: 134 AGGLALGLHPGG 145



 Score = 51.6 bits (122), Expect = 4e-06
 Identities = 57/196 (29%), Positives = 68/196 (34%), Gaps = 62/196 (31%)

Query: 2   AERGQQPPPAKRLCCRPGGGGGGGGSSGGGGGAGGGYSSACRPGPRAGGAAAAAACGGGA 61
           A   Q  P A          G GGG  GGGGGA GG S +C P      AA A       
Sbjct: 20  AASAQSAPLALVTSLAAAASGTGGG--GGGGGASGGTSGSCSPASSEPPAAPADRL---- 73

Query: 62  ALGLLPPGKTQSPESLLDIAARRVAEKWPFQRVEERFERIPEPVQRRIVYWSFPRSEREI 121
                   + +SP               P + +      +P+P                 
Sbjct: 74  --------RAESPS--------------PPRLLAAHCALLPKP----------------- 94

Query: 122 CMYSSFNTGGGAAGGPGDDSGGGGGAGGGGGGGSSSSPAATSAAATSAAAAAAAAAA--- 178
                   G   AGG     GGGG  GG GG    + P A +AAA +AAAAAA   A   
Sbjct: 95  --------GFLGAGG-----GGGGTGGGHGGPHHHAHPGAAAAAAAAAAAAAAGGLALGL 141

Query: 179 -AAAAAAGAGAPSVGA 193
               A  GAG P+  A
Sbjct: 142 HPGGAQGGAGLPAQAA 157



 Score = 44.3 bits (103), Expect = 7e-04
 Identities = 28/54 (51%), Positives = 29/54 (53%), Gaps = 1/54 (1%)

Query: 144 GGGAGGGGGGGSSSSPAATSAAATSAAAAAAAAAAAAAAAAGAGAPSVGAAGAA 197
           G G GGGG GG    P    A   +AAAAAAAAAAAAA     G    GA G A
Sbjct: 98  GAGGGGGGTGGGHGGP-HHHAHPGAAAAAAAAAAAAAAGGLALGLHPGGAQGGA 150



 Score = 40.8 bits (94), Expect = 0.008
 Identities = 29/73 (39%), Positives = 33/73 (45%), Gaps = 5/73 (6%)

Query: 133 AAGGPGDDSGGGGGAGGGGGGGSSSSPAATS--AAATSAAAAAAAAAAAAAAAAGAGAPS 190
           AA G G   GGGGG G  GG   S SPA++   AA      A + +     AA  A  P 
Sbjct: 37  AASGTG---GGGGGGGASGGTSGSCSPASSEPPAAPADRLRAESPSPPRLLAAHCALLPK 93

Query: 191 VGAAGAADGGDET 203
            G  GA  GG  T
Sbjct: 94  PGFLGAGGGGGGT 106


>gi|24432032 zinc finger protein 503 [Homo sapiens]
          Length = 646

 Score = 52.4 bits (124), Expect = 3e-06
 Identities = 58/249 (23%), Positives = 83/249 (33%), Gaps = 76/249 (30%)

Query: 23  GGGGSSGGGGGAGGGYSSACRPGPRAGGAAAAAACGGGAALGLLPP-------------- 68
           GGGG  GGGGGA   ++SA        G  ++ A      +  +PP              
Sbjct: 17  GGGGGGGGGGGADPAWTSALSGNSSGPGPGSSPAGSTKPFVHAVPPSDPLRQANRLPIKV 76

Query: 69  --------GKTQSPESLLDIAARRV------AEKWPFQRVEERFERIPEPVQRRIVYWSF 114
                   G    PE L  + +  V      A+K P   + +   +I +P          
Sbjct: 77  LKMLTARTGHILHPEYLQPLPSTPVSPIELDAKKSPLALLAQTCSQIGKPD--------- 127

Query: 115 PRSEREICMYSSFNTGGGAAGG-------------------------------------- 136
           P    ++   +S   G G AGG                                      
Sbjct: 128 PSPSSKLSSVASNGGGAGGAGGGAAGDKDTKSGPLKLSDIGVEDKSSFKPYSKPGSDKKE 187

Query: 137 PGDDSGGGGGAGGGGGGGSSSSPAATSAAAT-SAAAAAAAAAAAAAAAAGAGAPSVGAAG 195
           PG   GGGGG GGGGGG SS        +AT         + +++A+A   G     A G
Sbjct: 188 PGGGGGGGGGGGGGGGGVSSEKSGFRVPSATCQPFTPRTGSPSSSASACSPGGMLSSAGG 247

Query: 196 AADGGDETR 204
           A +G D+ +
Sbjct: 248 APEGKDDKK 256



 Score = 47.4 bits (111), Expect = 8e-05
 Identities = 32/74 (43%), Positives = 39/74 (52%), Gaps = 18/74 (24%)

Query: 18  PGGGGGGGGSSGGGGGAGGGYSS----------ACRP-GPRAGG-AAAAAACGGGAAL-- 63
           PGGGGGGG   GGGGG GGG SS           C+P  PR G  +++A+AC  G  L  
Sbjct: 188 PGGGGGGG---GGGGGGGGGVSSEKSGFRVPSATCQPFTPRTGSPSSSASACSPGGMLSS 244

Query: 64  -GLLPPGKTQSPES 76
            G  P GK    ++
Sbjct: 245 AGGAPEGKDDKKDT 258



 Score = 35.4 bits (80), Expect = 0.33
 Identities = 24/69 (34%), Positives = 32/69 (46%), Gaps = 10/69 (14%)

Query: 141 SGGGGGAGGGGGGGSSSSPAATSAAATSAAAAAAAAAAAAAAAAGAGAPSVGAAGAADG- 199
           SGGGGG GGGGG            A TSA +  ++     ++ AG+  P V A   +D  
Sbjct: 16  SGGGGGGGGGGG---------ADPAWTSALSGNSSGPGPGSSPAGSTKPFVHAVPPSDPL 66

Query: 200 GDETRLPFR 208
               RLP +
Sbjct: 67  RQANRLPIK 75



 Score = 32.3 bits (72), Expect = 2.8
 Identities = 23/63 (36%), Positives = 26/63 (41%), Gaps = 13/63 (20%)

Query: 9   PPAKRLCCRPGG--GGGGGGSSG---------GGGGAGGGYSSACRPGPRAGGAAAAAAC 57
           P +    C PGG     GG   G         GGGG G G +SA   G   G A    +C
Sbjct: 229 PSSSASACSPGGMLSSAGGAPEGKDDKKDTDVGGGGKGTGGASA--EGGPTGLAHGRISC 286

Query: 58  GGG 60
           GGG
Sbjct: 287 GGG 289


>gi|119220564 one cut domain, family member 2 [Homo sapiens]
          Length = 504

 Score = 52.0 bits (123), Expect = 3e-06
 Identities = 38/111 (34%), Positives = 45/111 (40%), Gaps = 17/111 (15%)

Query: 120 EICMYSSFNTGGGAAGGPGDDSGGGGGAGGGGGGGSSSSPAATSAAATSAAAAAA----- 174
           E+ M S     G A GG G   GGGGG GGGG G      A+ S       AA +     
Sbjct: 23  ELTMESLGTLHGPAGGGSGGGGGGGGGGGGGGPGHEQELLASPSPHHAGRGAAGSLRGPP 82

Query: 175 ---------AAAAAAAAAAGAGAPSVGAAGAADGGD---ETRLPFRRGIAL 213
                      AAAAAAAA   A     A   DGGD   E  +P    +++
Sbjct: 83  PPPTAHQELGTAAAAAAAASRSAMVTSMASILDGGDYRPELSIPLHHAMSM 133



 Score = 43.5 bits (101), Expect = 0.001
 Identities = 28/75 (37%), Positives = 30/75 (40%), Gaps = 10/75 (13%)

Query: 18  PGGGGGGGGSSGGGGGAGGG----YSSACRPGPRAGGAAAAAACGGGAALGLLPPGKTQS 73
           P GGG GGG  GGGGG GGG          P P   G  AA +  G       PP  T  
Sbjct: 35  PAGGGSGGGGGGGGGGGGGGPGHEQELLASPSPHHAGRGAAGSLRGP------PPPPTAH 88

Query: 74  PESLLDIAARRVAEK 88
            E     AA   A +
Sbjct: 89  QELGTAAAAAAAASR 103


>gi|33188461 GATA binding protein 4 [Homo sapiens]
          Length = 442

 Score = 51.6 bits (122), Expect = 4e-06
 Identities = 52/161 (32%), Positives = 61/161 (37%), Gaps = 36/161 (22%)

Query: 20  GGGGGGGSSGGGGGAGGGYSSACRPGPRAGGAAAAAACGGGAALGLLPPGKTQS-PESLL 78
           GGG G  S G  GG+ GG +S   PG + G    + A   GAA    P     S P +  
Sbjct: 56  GGGAGSASGGASGGSSGGAASGAGPGTQQGSPGWSQAGADGAAYTPPPVSPRFSFPGTTG 115

Query: 79  DIAARRVAEKWPFQRVEERFERIPEPVQRRIVYWSFPRSEREICMYSSFNTGGGAAGGPG 138
            +AA   A                              + RE   YSS   GGGAAG   
Sbjct: 116 SLAAAAAAA-----------------------------AAREAAAYSS---GGGAAGA-- 141

Query: 139 DDSGGGGGAGGGGGGGSSSSPAATSAAATSAAAAAAAAAAA 179
               G    G  G  GS SSP     A   A+ AAAAAA+A
Sbjct: 142 -GLAGREQYGRAGFAGSYSSPYPAYMADVGASWAAAAAASA 181



 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 41/115 (35%), Positives = 48/115 (41%), Gaps = 25/115 (21%)

Query: 110 VYWSFPRSEREICMYSSFNTGGGAAGGPGDDSGG--GGGAGGGGGGGSSSSPAATSAAAT 167
           VY   PR    + +  S+  GGGA    G  SGG  GG A G G G    SP  + A A 
Sbjct: 37  VYVPTPRVPSSV-LGLSYLQGGGAGSASGGASGGSSGGAASGAGPGTQQGSPGWSQAGAD 95

Query: 168 ----------------------SAAAAAAAAAAAAAAAAGAGAPSVGAAGAADGG 200
                                 +AAAAAAAA  AAA ++G GA   G AG    G
Sbjct: 96  GAAYTPPPVSPRFSFPGTTGSLAAAAAAAAAREAAAYSSGGGAAGAGLAGREQYG 150



 Score = 42.0 bits (97), Expect = 0.004
 Identities = 31/89 (34%), Positives = 41/89 (46%), Gaps = 16/89 (17%)

Query: 125 SSFNTGGGAAG-GPGDDSGGGGGAGGGGGG---------------GSSSSPAATSAAATS 168
           S  ++GG A+G GPG   G  G +  G  G               G++ S AA +AAA +
Sbjct: 67  SGGSSGGAASGAGPGTQQGSPGWSQAGADGAAYTPPPVSPRFSFPGTTGSLAAAAAAAAA 126

Query: 169 AAAAAAAAAAAAAAAAGAGAPSVGAAGAA 197
             AAA ++   AA A  AG    G AG A
Sbjct: 127 REAAAYSSGGGAAGAGLAGREQYGRAGFA 155



 Score = 33.9 bits (76), Expect = 0.97
 Identities = 22/77 (28%), Positives = 28/77 (36%)

Query: 123 MYSSFNTGGGAAGGPGDDSGGGGGAGGGGGGGSSSSPAATSAAATSAAAAAAAAAAAAAA 182
           MY S          PG    GG GA   G G +SS     +    S+    +      A 
Sbjct: 1   MYQSLAMAANHGPPPGAYEAGGPGAFMHGAGAASSPVYVPTPRVPSSVLGLSYLQGGGAG 60

Query: 183 AAGAGAPSVGAAGAADG 199
           +A  GA    + GAA G
Sbjct: 61  SASGGASGGSSGGAASG 77


>gi|4507163 SRY (sex determining region Y)-box 4 [Homo sapiens]
          Length = 474

 Score = 51.6 bits (122), Expect = 4e-06
 Identities = 35/87 (40%), Positives = 39/87 (44%), Gaps = 19/87 (21%)

Query: 130 GGGAAGGPGDDSGGGGGAGGGG-------------------GGGSSSSPAATSAAATSAA 170
           GGG  GG  +  GGGGGA GGG                   GGG S   A    A     
Sbjct: 167 GGGGGGGSSNAGGGGGGASGGGANSKPAQKKSCGSKVAGGAGGGVSKPHAKLILAGGGGG 226

Query: 171 AAAAAAAAAAAAAAGAGAPSVGAAGAA 197
             AAAAAAA+ AA  AGA ++   GAA
Sbjct: 227 GKAAAAAAASFAAEQAGAAALLPLGAA 253



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 42/148 (28%), Positives = 60/148 (40%), Gaps = 19/148 (12%)

Query: 72  QSPESLLDIAARRVAEKWPFQRVEERFERIPEPVQRRIV----YWSFPRSEREICMYSSF 127
           QSP+      ++R+ ++W   +  ++   I E  + R+     Y  +    R+     + 
Sbjct: 80  QSPDMHNAEISKRLGKRWKLLKDSDKIPFIREAERLRLKHMADYPDYKYRPRKKVKSGNA 139

Query: 128 NTGGGAA-----GGPGDDSGGGGGAGGGGGGGSSSSPA------ATSAAATSAAAAAAAA 176
           N+   AA     G  GD  GG GG G GGGGG  SS A      A+   A S  A   + 
Sbjct: 140 NSSSSAAASSKPGEKGDKVGGSGGGGHGGGGGGGSSNAGGGGGGASGGGANSKPAQKKSC 199

Query: 177 AAAAAAAAGAGAPSVGA----AGAADGG 200
            +  A  AG G     A    AG   GG
Sbjct: 200 GSKVAGGAGGGVSKPHAKLILAGGGGGG 227



 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 54/195 (27%), Positives = 71/195 (36%), Gaps = 71/195 (36%)

Query: 17  RPGGGGGGGGSSGGGGGAGGGYSSACRPGPRAGGAAAAAACGGGAALGLLPPGKTQSPES 76
           +PG  G   G SGGGG  GGG           GG++ A   GGGA+ G    G    P  
Sbjct: 150 KPGEKGDKVGGSGGGGHGGGG----------GGGSSNAGGGGGGASGG----GANSKP-- 193

Query: 77  LLDIAARRVAEKWPFQRVEERFERIPEPVQRRIVYWSFPRSEREICMYSSFNTGGGAAGG 136
                                                   ++++ C        GGA GG
Sbjct: 194 ----------------------------------------AQKKSC---GSKVAGGAGGG 210

Query: 137 PGDDSGGGGGAGGGGGGGSSSSPAATSAAATSAAAAAAAAAAAA------------AAAA 184
                     AGGGGGG ++++ AA+ AA  + AAA     AAA            A+A+
Sbjct: 211 VSKPHAKLILAGGGGGGKAAAAAAASFAAEQAGAAALLPLGAAADHHSLYKARTPSASAS 270

Query: 185 GAGAPSVGAAGAADG 199
            + A S  AA AA G
Sbjct: 271 ASSAASASAALAAPG 285



 Score = 48.1 bits (113), Expect = 5e-05
 Identities = 61/213 (28%), Positives = 82/213 (38%), Gaps = 43/213 (20%)

Query: 21  GGGGGGSSGGG----------------GGAGGGYSSA----CRPGPRAGGAAAAAACGGG 60
           GGGGGG+SGGG                GGAGGG S         G   GG AAAAA    
Sbjct: 178 GGGGGGASGGGANSKPAQKKSCGSKVAGGAGGGVSKPHAKLILAGGGGGGKAAAAAAASF 237

Query: 61  AA-----LGLLPPGKTQSPESLLDIAARRVAEKWPFQRVEERFERIPEPVQRRIVYWSFP 115
           AA       LLP G      SL    AR  +              +  P +         
Sbjct: 238 AAEQAGAAALLPLGAAADHHSLYK--ARTPSASASASSAASASAALAAPGKHLA-----E 290

Query: 116 RSEREICMYSSFNTGGGAAGGPG---DDSGGGGGAGGGGGGGSSSSPAAT--SAAATSAA 170
           +  + + ++    T     GG G   D S   G     G G S  +P+ +  S+AA+S A
Sbjct: 291 KKVKRVYLFGGLGTSSSPVGGVGAGADPSDPLGLYEEEGAGCSPDAPSLSGRSSAASSPA 350

Query: 171 AAAAA------AAAAAAAAAGAGAPSVGAAGAA 197
           A  +       A+  AA+ A + APS  ++ A+
Sbjct: 351 AGRSPADHRGYASLRAASPAPSSAPSHASSSAS 383


>gi|18375613 dachshund homolog 1 isoform b [Homo sapiens]
          Length = 558

 Score = 51.6 bits (122), Expect = 4e-06
 Identities = 26/74 (35%), Positives = 39/74 (52%), Gaps = 1/74 (1%)

Query: 130 GGGAAGGPGDDSGGGGGAGGGGGGGSSSSPAATSAAATSAAAAAAAAAAAAAAAAGAGAP 189
           GGG +GG G  SG GGG GGGGGGGS+ +P   +A+  S       +A    A++     
Sbjct: 78  GGGGSGGGGGSSGNGGG-GGGGGGGSNCNPNLAAASNGSGGGGGGISAGGGVASSTPINA 136

Query: 190 SVGAAGAADGGDET 203
           S G++ ++     +
Sbjct: 137 STGSSSSSSSSSSS 150



 Score = 49.7 bits (117), Expect = 2e-05
 Identities = 23/76 (30%), Positives = 32/76 (42%)

Query: 128 NTGGGAAGGPGDDSGGGGGAGGGGGGGSSSSPAATSAAATSAAAAAAAAAAAAAAAAGAG 187
           +TGGG  GG     GG  G GGGGGGG   S    + AA S  +       +A     + 
Sbjct: 72  STGGGGGGGGSGGGGGSSGNGGGGGGGGGGSNCNPNLAAASNGSGGGGGGISAGGGVASS 131

Query: 188 APSVGAAGAADGGDET 203
            P   + G++     +
Sbjct: 132 TPINASTGSSSSSSSS 147



 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 24/49 (48%), Positives = 25/49 (51%), Gaps = 5/49 (10%)

Query: 19  GGGGGGGGSSGGGGGAGGGYSSACRPGPRA-----GGAAAAAACGGGAA 62
           G GGGGG S  GGGG GGG  S C P   A     GG     + GGG A
Sbjct: 81  GSGGGGGSSGNGGGGGGGGGGSNCNPNLAAASNGSGGGGGGISAGGGVA 129



 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 23/75 (30%), Positives = 46/75 (61%), Gaps = 11/75 (14%)

Query: 125 SSFNTGGGAAGGPGDD-----------SGGGGGAGGGGGGGSSSSPAATSAAATSAAAAA 173
           SS N GGG  GG G +           SGGGGG    GGG +SS+P   S  ++S+++++
Sbjct: 88  SSGNGGGGGGGGGGSNCNPNLAAASNGSGGGGGGISAGGGVASSTPINASTGSSSSSSSS 147

Query: 174 AAAAAAAAAAAGAGA 188
           +++++++++++ + +
Sbjct: 148 SSSSSSSSSSSSSSS 162



 Score = 43.1 bits (100), Expect = 0.002
 Identities = 20/79 (25%), Positives = 44/79 (55%), Gaps = 12/79 (15%)

Query: 130 GGGAAGGPGDDSGGGGGA------------GGGGGGGSSSSPAATSAAATSAAAAAAAAA 177
           GGG++G  G   GGGGG+             GGGGGG S+     S+   +A+  +++++
Sbjct: 85  GGGSSGNGGGGGGGGGGSNCNPNLAAASNGSGGGGGGISAGGGVASSTPINASTGSSSSS 144

Query: 178 AAAAAAAGAGAPSVGAAGA 196
           +++++++ + + S  ++ +
Sbjct: 145 SSSSSSSSSSSSSSSSSSS 163



 Score = 42.0 bits (97), Expect = 0.004
 Identities = 23/69 (33%), Positives = 29/69 (42%)

Query: 129 TGGGAAGGPGDDSGGGGGAGGGGGGGSSSSPAATSAAATSAAAAAAAAAAAAAAAAGAGA 188
           +   AA       GGGGG G GGGGGSS +          +      AAA+  +  G G 
Sbjct: 62  SAAAAAATVTSTGGGGGGGGSGGGGGSSGNGGGGGGGGGGSNCNPNLAAASNGSGGGGGG 121

Query: 189 PSVGAAGAA 197
            S G   A+
Sbjct: 122 ISAGGGVAS 130



 Score = 37.0 bits (84), Expect = 0.11
 Identities = 20/70 (28%), Positives = 27/70 (38%)

Query: 128 NTGGGAAGGPGDDSGGGGGAGGGGGGGSSSSPAATSAAATSAAAAAAAAAAAAAAAAGAG 187
           +    AA       GGGGG  GGGGG S +          S      AAA+  +   G G
Sbjct: 62  SAAAAAATVTSTGGGGGGGGSGGGGGSSGNGGGGGGGGGGSNCNPNLAAASNGSGGGGGG 121

Query: 188 APSVGAAGAA 197
             + G   ++
Sbjct: 122 ISAGGGVASS 131



 Score = 36.6 bits (83), Expect = 0.15
 Identities = 20/48 (41%), Positives = 24/48 (50%), Gaps = 4/48 (8%)

Query: 19  GGGGG----GGGSSGGGGGAGGGYSSACRPGPRAGGAAAAAACGGGAA 62
           GGGGG    GGG  GGGGG+    + A       GG    +A GG A+
Sbjct: 83  GGGGGSSGNGGGGGGGGGGSNCNPNLAAASNGSGGGGGGISAGGGVAS 130



 Score = 35.8 bits (81), Expect = 0.25
 Identities = 21/59 (35%), Positives = 31/59 (52%), Gaps = 15/59 (25%)

Query: 19  GGGGGGGGS------------SGGGGG---AGGGYSSACRPGPRAGGAAAAAACGGGAA 62
           GGGGGGGGS            SGGGGG   AGGG +S+       G ++++++    ++
Sbjct: 94  GGGGGGGGSNCNPNLAAASNGSGGGGGGISAGGGVASSTPINASTGSSSSSSSSSSSSS 152



 Score = 33.9 bits (76), Expect = 0.97
 Identities = 15/58 (25%), Positives = 37/58 (63%)

Query: 132 GAAGGPGDDSGGGGGAGGGGGGGSSSSPAATSAAATSAAAAAAAAAAAAAAAAGAGAP 189
           G+ GG G  S GGG A       S+ S +++S++++S+++++++++++++     G P
Sbjct: 114 GSGGGGGGISAGGGVASSTPINASTGSSSSSSSSSSSSSSSSSSSSSSSSCGPLPGKP 171



 Score = 30.8 bits (68), Expect = 8.2
 Identities = 18/73 (24%), Positives = 27/73 (36%)

Query: 128 NTGGGAAGGPGDDSGGGGGAGGGGGGGSSSSPAATSAAATSAAAAAAAAAAAAAAAAGAG 187
           +T   ++G     S          G  +SS P        ++AAAAAA   +     G G
Sbjct: 21  STSASSSGTTTSTSSATSSPAPSIGPPASSGPTLFRPEPIASAAAAAATVTSTGGGGGGG 80

Query: 188 APSVGAAGAADGG 200
               G   + +GG
Sbjct: 81  GSGGGGGSSGNGG 93


>gi|18375611 dachshund homolog 1 isoform a [Homo sapiens]
          Length = 706

 Score = 51.6 bits (122), Expect = 4e-06
 Identities = 26/74 (35%), Positives = 39/74 (52%), Gaps = 1/74 (1%)

Query: 130 GGGAAGGPGDDSGGGGGAGGGGGGGSSSSPAATSAAATSAAAAAAAAAAAAAAAAGAGAP 189
           GGG +GG G  SG GGG GGGGGGGS+ +P   +A+  S       +A    A++     
Sbjct: 78  GGGGSGGGGGSSGNGGG-GGGGGGGSNCNPNLAAASNGSGGGGGGISAGGGVASSTPINA 136

Query: 190 SVGAAGAADGGDET 203
           S G++ ++     +
Sbjct: 137 STGSSSSSSSSSSS 150



 Score = 49.7 bits (117), Expect = 2e-05
 Identities = 23/76 (30%), Positives = 32/76 (42%)

Query: 128 NTGGGAAGGPGDDSGGGGGAGGGGGGGSSSSPAATSAAATSAAAAAAAAAAAAAAAAGAG 187
           +TGGG  GG     GG  G GGGGGGG   S    + AA S  +       +A     + 
Sbjct: 72  STGGGGGGGGSGGGGGSSGNGGGGGGGGGGSNCNPNLAAASNGSGGGGGGISAGGGVASS 131

Query: 188 APSVGAAGAADGGDET 203
            P   + G++     +
Sbjct: 132 TPINASTGSSSSSSSS 147



 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 24/49 (48%), Positives = 25/49 (51%), Gaps = 5/49 (10%)

Query: 19  GGGGGGGGSSGGGGGAGGGYSSACRPGPRA-----GGAAAAAACGGGAA 62
           G GGGGG S  GGGG GGG  S C P   A     GG     + GGG A
Sbjct: 81  GSGGGGGSSGNGGGGGGGGGGSNCNPNLAAASNGSGGGGGGISAGGGVA 129



 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 23/75 (30%), Positives = 46/75 (61%), Gaps = 11/75 (14%)

Query: 125 SSFNTGGGAAGGPGDD-----------SGGGGGAGGGGGGGSSSSPAATSAAATSAAAAA 173
           SS N GGG  GG G +           SGGGGG    GGG +SS+P   S  ++S+++++
Sbjct: 88  SSGNGGGGGGGGGGSNCNPNLAAASNGSGGGGGGISAGGGVASSTPINASTGSSSSSSSS 147

Query: 174 AAAAAAAAAAAGAGA 188
           +++++++++++ + +
Sbjct: 148 SSSSSSSSSSSSSSS 162



 Score = 43.1 bits (100), Expect = 0.002
 Identities = 20/79 (25%), Positives = 44/79 (55%), Gaps = 12/79 (15%)

Query: 130 GGGAAGGPGDDSGGGGGA------------GGGGGGGSSSSPAATSAAATSAAAAAAAAA 177
           GGG++G  G   GGGGG+             GGGGGG S+     S+   +A+  +++++
Sbjct: 85  GGGSSGNGGGGGGGGGGSNCNPNLAAASNGSGGGGGGISAGGGVASSTPINASTGSSSSS 144

Query: 178 AAAAAAAGAGAPSVGAAGA 196
           +++++++ + + S  ++ +
Sbjct: 145 SSSSSSSSSSSSSSSSSSS 163



 Score = 42.0 bits (97), Expect = 0.004
 Identities = 23/69 (33%), Positives = 29/69 (42%)

Query: 129 TGGGAAGGPGDDSGGGGGAGGGGGGGSSSSPAATSAAATSAAAAAAAAAAAAAAAAGAGA 188
           +   AA       GGGGG G GGGGGSS +          +      AAA+  +  G G 
Sbjct: 62  SAAAAAATVTSTGGGGGGGGSGGGGGSSGNGGGGGGGGGGSNCNPNLAAASNGSGGGGGG 121

Query: 189 PSVGAAGAA 197
            S G   A+
Sbjct: 122 ISAGGGVAS 130



 Score = 37.0 bits (84), Expect = 0.11
 Identities = 20/70 (28%), Positives = 27/70 (38%)

Query: 128 NTGGGAAGGPGDDSGGGGGAGGGGGGGSSSSPAATSAAATSAAAAAAAAAAAAAAAAGAG 187
           +    AA       GGGGG  GGGGG S +          S      AAA+  +   G G
Sbjct: 62  SAAAAAATVTSTGGGGGGGGSGGGGGSSGNGGGGGGGGGGSNCNPNLAAASNGSGGGGGG 121

Query: 188 APSVGAAGAA 197
             + G   ++
Sbjct: 122 ISAGGGVASS 131



 Score = 36.6 bits (83), Expect = 0.15
 Identities = 20/48 (41%), Positives = 24/48 (50%), Gaps = 4/48 (8%)

Query: 19  GGGGG----GGGSSGGGGGAGGGYSSACRPGPRAGGAAAAAACGGGAA 62
           GGGGG    GGG  GGGGG+    + A       GG    +A GG A+
Sbjct: 83  GGGGGSSGNGGGGGGGGGGSNCNPNLAAASNGSGGGGGGISAGGGVAS 130



 Score = 35.8 bits (81), Expect = 0.25
 Identities = 21/59 (35%), Positives = 31/59 (52%), Gaps = 15/59 (25%)

Query: 19  GGGGGGGGS------------SGGGGG---AGGGYSSACRPGPRAGGAAAAAACGGGAA 62
           GGGGGGGGS            SGGGGG   AGGG +S+       G ++++++    ++
Sbjct: 94  GGGGGGGGSNCNPNLAAASNGSGGGGGGISAGGGVASSTPINASTGSSSSSSSSSSSSS 152



 Score = 33.9 bits (76), Expect = 0.97
 Identities = 15/58 (25%), Positives = 37/58 (63%)

Query: 132 GAAGGPGDDSGGGGGAGGGGGGGSSSSPAATSAAATSAAAAAAAAAAAAAAAAGAGAP 189
           G+ GG G  S GGG A       S+ S +++S++++S+++++++++++++     G P
Sbjct: 114 GSGGGGGGISAGGGVASSTPINASTGSSSSSSSSSSSSSSSSSSSSSSSSCGPLPGKP 171



 Score = 30.8 bits (68), Expect = 8.2
 Identities = 18/73 (24%), Positives = 27/73 (36%)

Query: 128 NTGGGAAGGPGDDSGGGGGAGGGGGGGSSSSPAATSAAATSAAAAAAAAAAAAAAAAGAG 187
           +T   ++G     S          G  +SS P        ++AAAAAA   +     G G
Sbjct: 21  STSASSSGTTTSTSSATSSPAPSIGPPASSGPTLFRPEPIASAAAAAATVTSTGGGGGGG 80

Query: 188 APSVGAAGAADGG 200
               G   + +GG
Sbjct: 81  GSGGGGGSSGNGG 93


>gi|18375609 dachshund homolog 1 isoform c [Homo sapiens]
          Length = 504

 Score = 51.6 bits (122), Expect = 4e-06
 Identities = 26/74 (35%), Positives = 39/74 (52%), Gaps = 1/74 (1%)

Query: 130 GGGAAGGPGDDSGGGGGAGGGGGGGSSSSPAATSAAATSAAAAAAAAAAAAAAAAGAGAP 189
           GGG +GG G  SG GGG GGGGGGGS+ +P   +A+  S       +A    A++     
Sbjct: 78  GGGGSGGGGGSSGNGGG-GGGGGGGSNCNPNLAAASNGSGGGGGGISAGGGVASSTPINA 136

Query: 190 SVGAAGAADGGDET 203
           S G++ ++     +
Sbjct: 137 STGSSSSSSSSSSS 150



 Score = 49.7 bits (117), Expect = 2e-05
 Identities = 23/76 (30%), Positives = 32/76 (42%)

Query: 128 NTGGGAAGGPGDDSGGGGGAGGGGGGGSSSSPAATSAAATSAAAAAAAAAAAAAAAAGAG 187
           +TGGG  GG     GG  G GGGGGGG   S    + AA S  +       +A     + 
Sbjct: 72  STGGGGGGGGSGGGGGSSGNGGGGGGGGGGSNCNPNLAAASNGSGGGGGGISAGGGVASS 131

Query: 188 APSVGAAGAADGGDET 203
            P   + G++     +
Sbjct: 132 TPINASTGSSSSSSSS 147



 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 27/56 (48%), Positives = 28/56 (50%), Gaps = 12/56 (21%)

Query: 19  GGGGGGGGSSG-------GGGGAGGGYSSACRPGPRA-----GGAAAAAACGGGAA 62
           GGGGGGGGS G       GGGG GGG  S C P   A     GG     + GGG A
Sbjct: 74  GGGGGGGGSGGGGGSSGNGGGGGGGGGGSNCNPNLAAASNGSGGGGGGISAGGGVA 129



 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 23/75 (30%), Positives = 46/75 (61%), Gaps = 11/75 (14%)

Query: 125 SSFNTGGGAAGGPGDD-----------SGGGGGAGGGGGGGSSSSPAATSAAATSAAAAA 173
           SS N GGG  GG G +           SGGGGG    GGG +SS+P   S  ++S+++++
Sbjct: 88  SSGNGGGGGGGGGGSNCNPNLAAASNGSGGGGGGISAGGGVASSTPINASTGSSSSSSSS 147

Query: 174 AAAAAAAAAAAGAGA 188
           +++++++++++ + +
Sbjct: 148 SSSSSSSSSSSSSSS 162



 Score = 43.1 bits (100), Expect = 0.002
 Identities = 20/79 (25%), Positives = 44/79 (55%), Gaps = 12/79 (15%)

Query: 130 GGGAAGGPGDDSGGGGGA------------GGGGGGGSSSSPAATSAAATSAAAAAAAAA 177
           GGG++G  G   GGGGG+             GGGGGG S+     S+   +A+  +++++
Sbjct: 85  GGGSSGNGGGGGGGGGGSNCNPNLAAASNGSGGGGGGISAGGGVASSTPINASTGSSSSS 144

Query: 178 AAAAAAAGAGAPSVGAAGA 196
           +++++++ + + S  ++ +
Sbjct: 145 SSSSSSSSSSSSSSSSSSS 163



 Score = 42.0 bits (97), Expect = 0.004
 Identities = 23/69 (33%), Positives = 29/69 (42%)

Query: 129 TGGGAAGGPGDDSGGGGGAGGGGGGGSSSSPAATSAAATSAAAAAAAAAAAAAAAAGAGA 188
           +   AA       GGGGG G GGGGGSS +          +      AAA+  +  G G 
Sbjct: 62  SAAAAAATVTSTGGGGGGGGSGGGGGSSGNGGGGGGGGGGSNCNPNLAAASNGSGGGGGG 121

Query: 189 PSVGAAGAA 197
            S G   A+
Sbjct: 122 ISAGGGVAS 130



 Score = 37.0 bits (84), Expect = 0.11
 Identities = 20/70 (28%), Positives = 27/70 (38%)

Query: 128 NTGGGAAGGPGDDSGGGGGAGGGGGGGSSSSPAATSAAATSAAAAAAAAAAAAAAAAGAG 187
           +    AA       GGGGG  GGGGG S +          S      AAA+  +   G G
Sbjct: 62  SAAAAAATVTSTGGGGGGGGSGGGGGSSGNGGGGGGGGGGSNCNPNLAAASNGSGGGGGG 121

Query: 188 APSVGAAGAA 197
             + G   ++
Sbjct: 122 ISAGGGVASS 131



 Score = 36.6 bits (83), Expect = 0.15
 Identities = 20/48 (41%), Positives = 24/48 (50%), Gaps = 4/48 (8%)

Query: 19  GGGGG----GGGSSGGGGGAGGGYSSACRPGPRAGGAAAAAACGGGAA 62
           GGGGG    GGG  GGGGG+    + A       GG    +A GG A+
Sbjct: 83  GGGGGSSGNGGGGGGGGGGSNCNPNLAAASNGSGGGGGGISAGGGVAS 130



 Score = 35.8 bits (81), Expect = 0.25
 Identities = 21/59 (35%), Positives = 31/59 (52%), Gaps = 15/59 (25%)

Query: 19  GGGGGGGGS------------SGGGGG---AGGGYSSACRPGPRAGGAAAAAACGGGAA 62
           GGGGGGGGS            SGGGGG   AGGG +S+       G ++++++    ++
Sbjct: 94  GGGGGGGGSNCNPNLAAASNGSGGGGGGISAGGGVASSTPINASTGSSSSSSSSSSSSS 152



 Score = 33.9 bits (76), Expect = 0.97
 Identities = 15/58 (25%), Positives = 37/58 (63%)

Query: 132 GAAGGPGDDSGGGGGAGGGGGGGSSSSPAATSAAATSAAAAAAAAAAAAAAAAGAGAP 189
           G+ GG G  S GGG A       S+ S +++S++++S+++++++++++++     G P
Sbjct: 114 GSGGGGGGISAGGGVASSTPINASTGSSSSSSSSSSSSSSSSSSSSSSSSCGPLPGKP 171



 Score = 30.8 bits (68), Expect = 8.2
 Identities = 18/73 (24%), Positives = 27/73 (36%)

Query: 128 NTGGGAAGGPGDDSGGGGGAGGGGGGGSSSSPAATSAAATSAAAAAAAAAAAAAAAAGAG 187
           +T   ++G     S          G  +SS P        ++AAAAAA   +     G G
Sbjct: 21  STSASSSGTTTSTSSATSSPAPSIGPPASSGPTLFRPEPIASAAAAAATVTSTGGGGGGG 80

Query: 188 APSVGAAGAADGG 200
               G   + +GG
Sbjct: 81  GSGGGGGSSGNGG 93


>gi|45439359 triple functional domain (PTPRF interacting) [Homo
            sapiens]
          Length = 3097

 Score = 51.6 bits (122), Expect = 4e-06
 Identities = 54/208 (25%), Positives = 80/208 (38%), Gaps = 54/208 (25%)

Query: 19   GGGGGGGGSSGGGGGAGGGYSSACRPGPRAGGAAAAAACGGGAALGLLPPGKTQSPESLL 78
            GGGGGG G SGGGGG+GGG +    P   +G +   ++CGG        P  ++S     
Sbjct: 2293 GGGGGGSGGSGGGGGSGGGGA----PSGGSGHSGGPSSCGGA-------PSTSRS----- 2336

Query: 79   DIAARRVAEKWPFQRVEERFERIPEPVQRR--IVYWSFPRSEREICMYSSFNTGGGAAGG 136
                              R  RIP+PV+    ++  S   S+ E    S  +T G +   
Sbjct: 2337 ------------------RPSRIPQPVRHHPPVLVSSAASSQAEADKMSGTSTPGPSLPP 2378

Query: 137  PGDDSGGGGGAGGGGGGGSSSSPAATSA---------------AATSAAAAAAAAAAAAA 181
            PG     G  A      G+ +  +   A               AA ++ ++  A A  A 
Sbjct: 2379 PGAAPEAGPSAPSRRPPGADAEGSEREAEPIPKMKVLESPRKGAANASGSSPDAPAKDAR 2438

Query: 182  AAAGA---GAPSVGAAGAADGGDETRLP 206
            A+ G    G P  GAA   +    + +P
Sbjct: 2439 ASLGTLPLGKPRAGAASPLNSPLSSAVP 2466



 Score = 43.5 bits (101), Expect = 0.001
 Identities = 39/133 (29%), Positives = 55/133 (41%), Gaps = 41/133 (30%)

Query: 124  YSSFNTGGGAAGGPGDDSGGGGGAGGG---GGGGSSSSPAATSAAATSA----------- 169
            Y   ++GGG  GG G   GGGG  GGG   GG G S  P++   A +++           
Sbjct: 2286 YQRNHSGGGGGGGSGGSGGGGGSGGGGAPSGGSGHSGGPSSCGGAPSTSRSRPSRIPQPV 2345

Query: 170  --------AAAAAAAAAA-----------------AAAAAGAGAPSVGAAGA-ADGGDET 203
                    ++AA++ A A                 AA  AG  APS    GA A+G +  
Sbjct: 2346 RHHPPVLVSSAASSQAEADKMSGTSTPGPSLPPPGAAPEAGPSAPSRRPPGADAEGSERE 2405

Query: 204  RLPFRRGIALLES 216
              P  + + +LES
Sbjct: 2406 AEPIPK-MKVLES 2417



 Score = 38.1 bits (87), Expect = 0.051
 Identities = 20/51 (39%), Positives = 27/51 (52%), Gaps = 5/51 (9%)

Query: 32 GGAGGGYSSACRPGPRAGGAAAAAACGGGAALGLLPPGKTQSPESLLDIAA 82
          G +GG  + A   GP A  +AA + CGGGA       G  ++ + L DIAA
Sbjct: 3  GSSGGAAAPAASSGPAAAASAAGSGCGGGAG-----EGAEEAAKDLADIAA 48



 Score = 30.8 bits (68), Expect = 8.2
 Identities = 19/56 (33%), Positives = 29/56 (51%), Gaps = 4/56 (7%)

Query: 162 TSAAATSAAAAAAAAAAAAAAAAGAGAPSVGAAGAADGGDETRLPFRRGIALLESG 217
           + ++  +AA AA++  AAAA+AAG+G       GA +G +E         A   SG
Sbjct: 2   SGSSGGAAAPAASSGPAAAASAAGSGC----GGGAGEGAEEAAKDLADIAAFFRSG 53



 Score = 30.8 bits (68), Expect = 8.2
 Identities = 22/54 (40%), Positives = 27/54 (50%), Gaps = 1/54 (1%)

Query: 156 SSSPAATSAAATSAAAAAAAAAAAAAAAAGAGAPSVGAAGAADGGDETRLPFRR 209
           SS  AA  AA++  AAAA+AA +     AG GA    A   AD     R  FR+
Sbjct: 4   SSGGAAAPAASSGPAAAASAAGSGCGGGAGEGAEE-AAKDLADIAAFFRSGFRK 56


>gi|20127580 BTB (POZ) domain containing 2 [Homo sapiens]
          Length = 525

 Score = 51.6 bits (122), Expect = 4e-06
 Identities = 36/88 (40%), Positives = 42/88 (47%), Gaps = 5/88 (5%)

Query: 133 AAGGPGDDSGGGGGAGGGGGGGSSSSPAATSAAATSAAAAAAAAAAAAAAAAGAG----- 187
           AAGG G  +    G G G G G S  P+A +AA  +   AAAAAAAAAAAAA  G     
Sbjct: 2   AAGGSGGRASCPPGVGVGPGTGGSPGPSANAAATPAPGNAAAAAAAAAAAAAAPGPTPPA 61

Query: 188 APSVGAAGAADGGDETRLPFRRGIALLE 215
            P  G    A G +        G A L+
Sbjct: 62  PPGPGTDAQAAGAERAEEAAGPGAAALQ 89



 Score = 51.2 bits (121), Expect = 6e-06
 Identities = 33/72 (45%), Positives = 37/72 (51%)

Query: 131 GGAAGGPGDDSGGGGGAGGGGGGGSSSSPAATSAAATSAAAAAAAAAAAAAAAAGAGAPS 190
           GG+ G      G G G G GG  G S++ AAT A   +AAAAAAAAAAAAA      AP 
Sbjct: 4   GGSGGRASCPPGVGVGPGTGGSPGPSANAAATPAPGNAAAAAAAAAAAAAAPGPTPPAPP 63

Query: 191 VGAAGAADGGDE 202
                A   G E
Sbjct: 64  GPGTDAQAAGAE 75



 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 29/78 (37%), Positives = 40/78 (51%)

Query: 129 TGGGAAGGPGDDSGGGGGAGGGGGGGSSSSPAATSAAATSAAAAAAAAAAAAAAAAGAGA 188
           +GG A+  PG   G G G   G    ++++PA  +AAA +AAAAAAAAA      A  G 
Sbjct: 6   SGGRASCPPGVGVGPGTGGSPGPSANAAATPAPGNAAAAAAAAAAAAAAPGPTPPAPPGP 65

Query: 189 PSVGAAGAADGGDETRLP 206
            +   A  A+  +E   P
Sbjct: 66  GTDAQAAGAERAEEAAGP 83



 Score = 39.3 bits (90), Expect = 0.023
 Identities = 24/56 (42%), Positives = 26/56 (46%), Gaps = 4/56 (7%)

Query: 13 RLCCRPGGGGGGGGSSGGGGGAGGGYSSACRPGPRAGGAAAAAACGGGAALGLLPP 68
          R  C PG G G     G GG  G   ++A  P P    AAAAAA    AA G  PP
Sbjct: 9  RASCPPGVGVG----PGTGGSPGPSANAAATPAPGNAAAAAAAAAAAAAAPGPTPP 60



 Score = 33.1 bits (74), Expect = 1.7
 Identities = 21/55 (38%), Positives = 23/55 (41%), Gaps = 5/55 (9%)

Query: 22 GGGGGSSGGGGGAGGGYSSACRPGPRAGGAAA-----AAACGGGAALGLLPPGKT 71
          GG GG +    G G G  +   PGP A  AA      AAA    AA     PG T
Sbjct: 4  GGSGGRASCPPGVGVGPGTGGSPGPSANAAATPAPGNAAAAAAAAAAAAAAPGPT 58


>gi|8051631 RNA binding protein (autoantigenic, hnRNP-associated
           with lethal yellow) long isoform [Homo sapiens]
          Length = 306

 Score = 51.6 bits (122), Expect = 4e-06
 Identities = 32/76 (42%), Positives = 34/76 (44%), Gaps = 18/76 (23%)

Query: 130 GGGAAGGPGDDSGGGGGAGGGGGGGSSSSPAATSAAATSAAAAAAAAAAAAAAAAGAGAP 189
           GGGA GG G    GGGG+GGGGGGGSS  PA      +                  AG P
Sbjct: 227 GGGAGGGGGGGGSGGGGSGGGGGGGSSRPPAPQENTTSE-----------------AGLP 269

Query: 190 SVGAAGAADGGDETRL 205
             G A   D GDE  L
Sbjct: 270 Q-GEARTRDDGDEEGL 284



 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 22/43 (51%), Positives = 25/43 (58%)

Query: 19  GGGGGGGGSSGGGGGAGGGYSSACRPGPRAGGAAAAAACGGGA 61
           GGGGGGGGS GGG G GGG  S+  P P+    + A    G A
Sbjct: 231 GGGGGGGGSGGGGSGGGGGGGSSRPPAPQENTTSEAGLPQGEA 273



 Score = 43.1 bits (100), Expect = 0.002
 Identities = 21/43 (48%), Positives = 24/43 (55%)

Query: 2   AERGQQPPPAKRLCCRPGGGGGGGGSSGGGGGAGGGYSSACRP 44
           AE+   P   K+      GGGGGGG SGGGG  GGG   + RP
Sbjct: 213 AEQKANPDGKKKGDGGGAGGGGGGGGSGGGGSGGGGGGGSSRP 255



 Score = 33.9 bits (76), Expect = 0.97
 Identities = 22/66 (33%), Positives = 26/66 (39%), Gaps = 10/66 (15%)

Query: 18  PGGGGGGGGSSGGGGGAGGGYSSACRPGPRAGGAAAAAACGGGAALGLLPPGKTQSPESL 77
           P G   G G   GGGG GGG          +GG  +    GGG++    P   T S   L
Sbjct: 219 PDGKKKGDGGGAGGGGGGGG----------SGGGGSGGGGGGGSSRPPAPQENTTSEAGL 268

Query: 78  LDIAAR 83
               AR
Sbjct: 269 PQGEAR 274


>gi|21396480 RNA binding protein (autoantigenic, hnRNP-associated
           with lethal yellow) short isoform [Homo sapiens]
          Length = 290

 Score = 51.6 bits (122), Expect = 4e-06
 Identities = 32/76 (42%), Positives = 34/76 (44%), Gaps = 18/76 (23%)

Query: 130 GGGAAGGPGDDSGGGGGAGGGGGGGSSSSPAATSAAATSAAAAAAAAAAAAAAAAGAGAP 189
           GGGA GG G    GGGG+GGGGGGGSS  PA      +                  AG P
Sbjct: 211 GGGAGGGGGGGGSGGGGSGGGGGGGSSRPPAPQENTTSE-----------------AGLP 253

Query: 190 SVGAAGAADGGDETRL 205
             G A   D GDE  L
Sbjct: 254 Q-GEARTRDDGDEEGL 268



 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 22/43 (51%), Positives = 25/43 (58%)

Query: 19  GGGGGGGGSSGGGGGAGGGYSSACRPGPRAGGAAAAAACGGGA 61
           GGGGGGGGS GGG G GGG  S+  P P+    + A    G A
Sbjct: 215 GGGGGGGGSGGGGSGGGGGGGSSRPPAPQENTTSEAGLPQGEA 257



 Score = 43.1 bits (100), Expect = 0.002
 Identities = 21/43 (48%), Positives = 24/43 (55%)

Query: 2   AERGQQPPPAKRLCCRPGGGGGGGGSSGGGGGAGGGYSSACRP 44
           AE+   P   K+      GGGGGGG SGGGG  GGG   + RP
Sbjct: 197 AEQKANPDGKKKGDGGGAGGGGGGGGSGGGGSGGGGGGGSSRP 239



 Score = 33.9 bits (76), Expect = 0.97
 Identities = 22/66 (33%), Positives = 26/66 (39%), Gaps = 10/66 (15%)

Query: 18  PGGGGGGGGSSGGGGGAGGGYSSACRPGPRAGGAAAAAACGGGAALGLLPPGKTQSPESL 77
           P G   G G   GGGG GGG          +GG  +    GGG++    P   T S   L
Sbjct: 203 PDGKKKGDGGGAGGGGGGGG----------SGGGGSGGGGGGGSSRPPAPQENTTSEAGL 252

Query: 78  LDIAAR 83
               AR
Sbjct: 253 PQGEAR 258


>gi|23510368 homeobox D11 [Homo sapiens]
          Length = 338

 Score = 51.2 bits (121), Expect = 6e-06
 Identities = 26/50 (52%), Positives = 30/50 (60%)

Query: 127 FNTGGGAAGGPGDDSGGGGGAGGGGGGGSSSSPAATSAAATSAAAAAAAA 176
           +  GGG     G  SGGG G GGGG GG +   AA +AAA +AAAA  AA
Sbjct: 75  YRGGGGGGSAGGGSSGGGPGGGGGGAGGYAPYYAAAAAAAAAAAAAEEAA 124



 Score = 51.2 bits (121), Expect = 6e-06
 Identities = 62/215 (28%), Positives = 75/215 (34%), Gaps = 37/215 (17%)

Query: 17  RPGGGGG--GGGSSGGGGGAGGGYSSACRPGPRAGGAAAAAACGGGAAL---GLLPPGKT 71
           R GGGGG  GGGSSGGG G GGG +    P   A  AAAAAA     A     LLPP   
Sbjct: 76  RGGGGGGSAGGGSSGGGPGGGGGGAGGYAPYYAAAAAAAAAAAAAEEAAMQRELLPPA-G 134

Query: 72  QSPESLLDIAARRVAEKWPFQRVEERFERIPEPVQRRIVYWSFPRSEREICMYSSFNTGG 131
           + P+ L        A   P              V R  +            +   F+   
Sbjct: 135 RRPDVLFKAPEPVCAAPGPPHGPAGAASNFYSAVGRNGI------------LPQGFDQFY 182

Query: 132 GAAGGP-----------------GDDSGGGGGAGGGGGGGSSSSPAATSAAATSAAAAAA 174
            AA GP                 G    G    G GGGGGS  + A   +    AA  + 
Sbjct: 183 EAAPGPPFAGPQPPPPPAPPQPEGAADKGDPRTGAGGGGGSPCTKATPGSEPKGAAEGSG 242

Query: 175 AAAAAAAAAAGAGAPSVGAAGAADGGDETRLPFRR 209
                    AGA   S  +A A     + R P+ +
Sbjct: 243 GDGEGPPGEAGAEKSS--SAVAPQRSRKKRCPYTK 275



 Score = 43.9 bits (102), Expect = 0.001
 Identities = 30/61 (49%), Positives = 31/61 (50%), Gaps = 2/61 (3%)

Query: 137 PGDDSGGGGGAGGG--GGGGSSSSPAATSAAATSAAAAAAAAAAAAAAAAGAGAPSVGAA 194
           P    GGGG AGGG  GGG       A   A   AAAAAAAAAAAAA  A      +  A
Sbjct: 74  PYRGGGGGGSAGGGSSGGGPGGGGGGAGGYAPYYAAAAAAAAAAAAAEEAAMQRELLPPA 133

Query: 195 G 195
           G
Sbjct: 134 G 134



 Score = 38.1 bits (87), Expect = 0.051
 Identities = 28/84 (33%), Positives = 37/84 (44%), Gaps = 6/84 (7%)

Query: 5   GQQPPPAKRLCCRPGGGGGGGGSSGGGGGAGGGYSSACRPGPRAGGAAAAAACGGGAALG 64
           G QPPP      +P G    G    G GG GG   +   PG    GAA  +   GG   G
Sbjct: 192 GPQPPPPPAPP-QPEGAADKGDPRTGAGGGGGSPCTKATPGSEPKGAAEGS---GGDGEG 247

Query: 65  LLPPGKTQSPESLLDIAARRVAEK 88
             PPG+  + +S   +A +R  +K
Sbjct: 248 --PPGEAGAEKSSSAVAPQRSRKK 269


>gi|30179900 SRY (sex determining region Y)-box 1 [Homo sapiens]
          Length = 391

 Score = 51.2 bits (121), Expect = 6e-06
 Identities = 56/210 (26%), Positives = 80/210 (38%), Gaps = 43/210 (20%)

Query: 18  PGGGGGGGGSSGGGGGAGGGYSSACRPGPRAGGAAAAAACGGGAALGLLPPGKTQSPESL 77
           P G GGGGG  GGGGG GG  ++  R   R   A    + G    +        ++P+  
Sbjct: 25  PAGAGGGGGGGGGGGGGGGAKANQDRV-KRPMNAFMVWSRGQRRKMA------QENPKMH 77

Query: 78  LDIAARRVAEKWPFQRVEERFERIPEPVQRRIVY--------WSFPRSEREICMYSSFNT 129
               ++R+  +W      E+   I E  + R ++        +   R  + +     ++ 
Sbjct: 78  NSEISKRLGAEWKVMSEAEKRPFIDEAKRLRALHMKEHPDYKYRPRRKTKTLLKKDKYSL 137

Query: 130 GGG--AAGGPGDDSGGGGGA---------------------GGGGGGGSSSSPAATSAAA 166
            GG  AAG     +GGGG A                     GG  GGG +      + A 
Sbjct: 138 AGGLLAAG-----AGGGGAAVAMGVGVGVGAAAVGQRLESPGGAAGGGYAHVNGWANGAY 192

Query: 167 TSAAAAAAAAAAAAAAAAGAGAPSVGAAGA 196
             + AAAAAAAA    A  A     GA GA
Sbjct: 193 PGSVAAAAAAAAMMQEAQLAYGQHPGAGGA 222



 Score = 39.7 bits (91), Expect = 0.018
 Identities = 43/179 (24%), Positives = 63/179 (35%), Gaps = 24/179 (13%)

Query: 25  GGSSGGGGGAGGGYSSACRPGPRAGGAAAAAACGGGA-ALGLLPPGKTQSPESLLDIAAR 83
           GG++GGG     G+++   PG  A  AAAAA       A G  P      P +       
Sbjct: 174 GGAAGGGYAHVNGWANGAYPGSVAAAAAAAAMMQEAQLAYGQHPGAGGAHPHA------- 226

Query: 84  RVAEKWPFQRVEERFERIPEPVQRRIVYWSFPRSEREICMYSSFNTGGG-----AAGGPG 138
                 P           P+P+ R          +     YS  +   G      +G  G
Sbjct: 227 --HPAHPHPHHPHAHPHNPQPMHRY---------DMGALQYSPISNSQGYMSASPSGYGG 275

Query: 139 DDSGGGGGAGGGGGGGSSSSPAATSAAATSAAAAAAAAAAAAAAAAGAGAPSVGAAGAA 197
              G    A    GG   +S  A +AAA +A++ A  A  +   +  +G+P   A   A
Sbjct: 276 LPYGAAAAAAAAAGGAHQNSAVAAAAAAAAASSGALGALGSLVKSEPSGSPPAPAHSRA 334



 Score = 38.1 bits (87), Expect = 0.051
 Identities = 18/41 (43%), Positives = 23/41 (56%), Gaps = 5/41 (12%)

Query: 123 MYSSFNTGGGAAG-----GPGDDSGGGGGAGGGGGGGSSSS 158
           M +  ++ GGA       GP    GGGGG GGGGGGG + +
Sbjct: 6   METDLHSPGGAQAPTNLSGPAGAGGGGGGGGGGGGGGGAKA 46



 Score = 31.2 bits (69), Expect = 6.3
 Identities = 16/31 (51%), Positives = 17/31 (54%), Gaps = 2/31 (6%)

Query: 132 GAAGGPGDDSG--GGGGAGGGGGGGSSSSPA 160
           G A  P + SG  G GG GGGGGGG     A
Sbjct: 14  GGAQAPTNLSGPAGAGGGGGGGGGGGGGGGA 44


>gi|73476377 LBXCOR1 homolog [Homo sapiens]
          Length = 921

 Score = 51.2 bits (121), Expect = 6e-06
 Identities = 79/284 (27%), Positives = 92/284 (32%), Gaps = 88/284 (30%)

Query: 2   AERGQQPPPAKRLCCRPGGGGGGGGSSGGGGGAGGGYSSACRPGPRAGGAAAAAACGGGA 61
           AE    PPP K L C      G  G        G G ++       A G A     GGGA
Sbjct: 270 AEMAPGPPPHKSLRCGEDEAAGPPGPPPPHPQRGLGLATG------ASGPAGPGGPGGGA 323

Query: 62  ALGLLPPGKTQSPESLLDIAARRVAEKWPFQRVEERFERIPEPVQRRIVYWSFPRSEREI 121
            +   P     S    L             Q++       P P      +   P+ +  +
Sbjct: 324 GVRSYPVIPVPSKGFGL------------LQKLPPPL--FPHPYGFPTAFGLCPKKDDPV 369

Query: 122 CMYSSFNTGGGAAGGPGDDSGGGG-GAGGGGGG---------------------GSSSSP 159
                    G   GGPG  SGGGG G GGG GG                     G   S 
Sbjct: 370 L------GAGEPKGGPGTGSGGGGAGTGGGAGGPGASHLPPGAGAGPGGGAMFWGHQPSG 423

Query: 160 AATSAAATSAAAAA------------------------------------AAAAAAAAAA 183
           AA  AAA +AAAAA                                    AAAAAAAAAA
Sbjct: 424 AAKDAAAVAAAAAAATVYPTFPMFWPAAGSLPVPSYPAAQSQAKAVAAAVAAAAAAAAAA 483

Query: 184 AGAGAPSV--GAAGAADG--GDETRLPFRRGIALLESGCVDNVL 223
           AG+GAP    GA  A +   G E R P       L+    D  L
Sbjct: 484 AGSGAPEPLDGAEPAKESGLGAEERCPSALSRGPLDEDGTDEAL 527


>gi|84570137 homeobox B3 [Homo sapiens]
          Length = 431

 Score = 50.8 bits (120), Expect = 8e-06
 Identities = 26/47 (55%), Positives = 28/47 (59%), Gaps = 2/47 (4%)

Query: 130 GGGAAGGPGDDSGGGGGAGGGGGGGSSSSPAATSAAATSAAAAAAAA 176
           GGG  GG G  SGG GG GGGGGGG  S P   SAA+  A  A  +A
Sbjct: 154 GGGGGGGGGGGSGGSGGGGGGGGGGDKSPPG--SAASKRARTAYTSA 198



 Score = 44.7 bits (104), Expect = 5e-04
 Identities = 23/42 (54%), Positives = 23/42 (54%), Gaps = 2/42 (4%)

Query: 16  CRPGGGGGGGGSSG--GGGGAGGGYSSACRPGPRAGGAAAAA 55
           C  GGGGGGGG SG  GGGG GGG      PG  A   A  A
Sbjct: 153 CGGGGGGGGGGGSGGSGGGGGGGGGGDKSPPGSAASKRARTA 194



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 24/72 (33%), Positives = 33/72 (45%), Gaps = 3/72 (4%)

Query: 107 RRIVYWSFPRSEREICMYSSFNTGGGAAGGPGDDSGGGGGA---GGGGGGGSSSSPAATS 163
           ++I  W     +      +S  T  G  GG G   GGG G    GGGGGGG   SP  ++
Sbjct: 127 KQIFPWMKESRQTSKLKNNSPGTAEGCGGGGGGGGGGGSGGSGGGGGGGGGGDKSPPGSA 186

Query: 164 AAATSAAAAAAA 175
           A+  +  A  +A
Sbjct: 187 ASKRARTAYTSA 198



 Score = 38.5 bits (88), Expect = 0.039
 Identities = 21/55 (38%), Positives = 24/55 (43%)

Query: 137 PGDDSGGGGGAGGGGGGGSSSSPAATSAAATSAAAAAAAAAAAAAAAAGAGAPSV 191
           PG   G GGG GGGGGGGS  S            +   +AA+  A  A   A  V
Sbjct: 147 PGTAEGCGGGGGGGGGGGSGGSGGGGGGGGGGDKSPPGSAASKRARTAYTSAQLV 201



 Score = 37.7 bits (86), Expect = 0.067
 Identities = 18/51 (35%), Positives = 22/51 (43%)

Query: 136 GPGDDSGGGGGAGGGGGGGSSSSPAATSAAATSAAAAAAAAAAAAAAAAGA 186
           G  +  GGGGG GGGGG G S            +   +AA+  A  A   A
Sbjct: 148 GTAEGCGGGGGGGGGGGSGGSGGGGGGGGGGDKSPPGSAASKRARTAYTSA 198



 Score = 34.7 bits (78), Expect = 0.57
 Identities = 23/70 (32%), Positives = 27/70 (38%), Gaps = 14/70 (20%)

Query: 18  PGGGGGGGGSSGGGGGAGGGYSSACRPGPRAGGAAAAAACGGGAALGLLPPGKTQSPESL 77
           PG   G GG  GGGGG G G       G   GG       GGG      PPG   S  + 
Sbjct: 147 PGTAEGCGGGGGGGGGGGSG-------GSGGGG-------GGGGGGDKSPPGSAASKRAR 192

Query: 78  LDIAARRVAE 87
               + ++ E
Sbjct: 193 TAYTSAQLVE 202


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.133    0.403 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 48,064,592
Number of Sequences: 37866
Number of extensions: 2422127
Number of successful extensions: 66441
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 748
Number of HSP's successfully gapped in prelim test: 318
Number of HSP's that attempted gapping in prelim test: 25495
Number of HSP's gapped (non-prelim): 21093
length of query: 1215
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1101
effective length of database: 13,930,794
effective search space: 15337804194
effective search space used: 15337804194
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 68 (30.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

CSHL Press