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Search of human proteins with 210032580
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|210032580 SET domain containing 1B [Homo sapiens]
(1923 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|210032580 SET domain containing 1B [Homo sapiens] 3982 0.0
gi|55741677 SET domain containing 1A [Homo sapiens] 684 0.0
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa... 178 4e-44
gi|56550039 myeloid/lymphoid or mixed-lineage leukemia protein [... 155 3e-37
gi|91718902 myeloid/lymphoid or mixed-lineage leukemia 3 [Homo s... 137 1e-31
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 134 9e-31
gi|160707881 formin 2 [Homo sapiens] 115 5e-25
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 112 5e-24
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 104 9e-22
gi|163965366 nascent polypeptide-associated complex alpha subuni... 104 9e-22
gi|119395760 diaphanous 1 isoform 2 [Homo sapiens] 103 2e-21
gi|119395758 diaphanous 1 isoform 1 [Homo sapiens] 103 2e-21
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] 103 2e-21
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] 103 2e-21
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] 103 2e-21
gi|7706501 WW domain binding protein 11 [Homo sapiens] 103 2e-21
gi|153792074 proline rich 12 [Homo sapiens] 102 3e-21
gi|23510384 enhancer of zeste 2 isoform b [Homo sapiens] 102 4e-21
gi|21361095 enhancer of zeste 2 isoform a [Homo sapiens] 102 4e-21
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 102 5e-21
gi|19923202 enhancer of zeste homolog 1 [Homo sapiens] 102 5e-21
gi|209862789 microtubule associated monoxygenase, calponin and L... 102 5e-21
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 101 6e-21
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 101 6e-21
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 101 6e-21
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 101 6e-21
gi|150417989 cyclin K isoform 1 [Homo sapiens] 101 6e-21
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo... 100 2e-20
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ... 100 2e-20
gi|116256464 hypothetical protein LOC343990 [Homo sapiens] 99 4e-20
>gi|210032580 SET domain containing 1B [Homo sapiens]
Length = 1923
Score = 3982 bits (10326), Expect = 0.0
Identities = 1923/1923 (100%), Positives = 1923/1923 (100%)
Query: 1 MENSHPPHHHHQQPPPQPGPSGERRNHHWRSYKLMIDPALKKGHHKLYRYDGQHFSLAMS 60
MENSHPPHHHHQQPPPQPGPSGERRNHHWRSYKLMIDPALKKGHHKLYRYDGQHFSLAMS
Sbjct: 1 MENSHPPHHHHQQPPPQPGPSGERRNHHWRSYKLMIDPALKKGHHKLYRYDGQHFSLAMS 60
Query: 61 SNRPVEIVEDPRVVGIWTKNKELELSVPKFKIDEFYVGPVPPKQVTFAKLNDNIRENFLR 120
SNRPVEIVEDPRVVGIWTKNKELELSVPKFKIDEFYVGPVPPKQVTFAKLNDNIRENFLR
Sbjct: 61 SNRPVEIVEDPRVVGIWTKNKELELSVPKFKIDEFYVGPVPPKQVTFAKLNDNIRENFLR 120
Query: 121 DMCKKYGEVEEVEILYNPKTKKHLGIAKVVFATVRGAKDAVQHLHSTSVMGNIIHVELDT 180
DMCKKYGEVEEVEILYNPKTKKHLGIAKVVFATVRGAKDAVQHLHSTSVMGNIIHVELDT
Sbjct: 121 DMCKKYGEVEEVEILYNPKTKKHLGIAKVVFATVRGAKDAVQHLHSTSVMGNIIHVELDT 180
Query: 181 KGETRMRFYELLVTGRYTPQTLPVGELDAVSPIVNETLQLSDALKRLKDGGLSAGCGSGS 240
KGETRMRFYELLVTGRYTPQTLPVGELDAVSPIVNETLQLSDALKRLKDGGLSAGCGSGS
Sbjct: 181 KGETRMRFYELLVTGRYTPQTLPVGELDAVSPIVNETLQLSDALKRLKDGGLSAGCGSGS 240
Query: 241 SSVTPNSGGTPFSQDTAYSSCRLDTPNSYGQGTPLTPRLGTPFSQDSSYSSRQPTPSYLF 300
SSVTPNSGGTPFSQDTAYSSCRLDTPNSYGQGTPLTPRLGTPFSQDSSYSSRQPTPSYLF
Sbjct: 241 SSVTPNSGGTPFSQDTAYSSCRLDTPNSYGQGTPLTPRLGTPFSQDSSYSSRQPTPSYLF 300
Query: 301 SQDPAVTFKARRHESKFTDAYNRRHEHHYVHNSPAVTAVAGATAAFRGSSDLPFGAVGGT 360
SQDPAVTFKARRHESKFTDAYNRRHEHHYVHNSPAVTAVAGATAAFRGSSDLPFGAVGGT
Sbjct: 301 SQDPAVTFKARRHESKFTDAYNRRHEHHYVHNSPAVTAVAGATAAFRGSSDLPFGAVGGT 360
Query: 361 GGSSGPPFKAQPQDSATFAHTPPPAQATPAPGFKSAFSPYQTPVAHFPPPPEEPTATAAF 420
GGSSGPPFKAQPQDSATFAHTPPPAQATPAPGFKSAFSPYQTPVAHFPPPPEEPTATAAF
Sbjct: 361 GGSSGPPFKAQPQDSATFAHTPPPAQATPAPGFKSAFSPYQTPVAHFPPPPEEPTATAAF 420
Query: 421 GARDSGEFRRAPAPPPLPPAEPLAKEKPGTPPGPPPPDTNSMELGGRPTFGWSPEPCDSP 480
GARDSGEFRRAPAPPPLPPAEPLAKEKPGTPPGPPPPDTNSMELGGRPTFGWSPEPCDSP
Sbjct: 421 GARDSGEFRRAPAPPPLPPAEPLAKEKPGTPPGPPPPDTNSMELGGRPTFGWSPEPCDSP 480
Query: 481 GTPTLESSPAGPEKPHDSLDSRIEMLLKEQRTKLLFLREPDSDTELQMEGSPISSSSSQL 540
GTPTLESSPAGPEKPHDSLDSRIEMLLKEQRTKLLFLREPDSDTELQMEGSPISSSSSQL
Sbjct: 481 GTPTLESSPAGPEKPHDSLDSRIEMLLKEQRTKLLFLREPDSDTELQMEGSPISSSSSQL 540
Query: 541 SPLAPFGTNSQPGFRGPTPPSSRPSSTGLEDISPTPLPDSDEDEELDLGLGPRPPPEPGP 600
SPLAPFGTNSQPGFRGPTPPSSRPSSTGLEDISPTPLPDSDEDEELDLGLGPRPPPEPGP
Sbjct: 541 SPLAPFGTNSQPGFRGPTPPSSRPSSTGLEDISPTPLPDSDEDEELDLGLGPRPPPEPGP 600
Query: 601 PDPAGLLSQTAEVALDLVGDRTPTSEKMDEGQQSSGEDMEISDDEMPSAPITSADCPKPM 660
PDPAGLLSQTAEVALDLVGDRTPTSEKMDEGQQSSGEDMEISDDEMPSAPITSADCPKPM
Sbjct: 601 PDPAGLLSQTAEVALDLVGDRTPTSEKMDEGQQSSGEDMEISDDEMPSAPITSADCPKPM 660
Query: 661 VVTPGAAAVAAPSVLAPTLPLPPPPGFPPLPPPPPPPPPQPGFPMPPPLPPPPPPPPPAH 720
VVTPGAAAVAAPSVLAPTLPLPPPPGFPPLPPPPPPPPPQPGFPMPPPLPPPPPPPPPAH
Sbjct: 661 VVTPGAAAVAAPSVLAPTLPLPPPPGFPPLPPPPPPPPPQPGFPMPPPLPPPPPPPPPAH 720
Query: 721 PAVTVPPPPLPAPPGVPPPPILPPLPPFPPGLFPVMQVDMSHVLGGQWGGMPMSFQMQTQ 780
PAVTVPPPPLPAPPGVPPPPILPPLPPFPPGLFPVMQVDMSHVLGGQWGGMPMSFQMQTQ
Sbjct: 721 PAVTVPPPPLPAPPGVPPPPILPPLPPFPPGLFPVMQVDMSHVLGGQWGGMPMSFQMQTQ 780
Query: 781 VLSRLMTGQGACPYPPFMAAAAAAASAGLQFVNLPPYRGPFSLSNSGPGRGQHWPPLPKF 840
VLSRLMTGQGACPYPPFMAAAAAAASAGLQFVNLPPYRGPFSLSNSGPGRGQHWPPLPKF
Sbjct: 781 VLSRLMTGQGACPYPPFMAAAAAAASAGLQFVNLPPYRGPFSLSNSGPGRGQHWPPLPKF 840
Query: 841 DPSVPPPGYMPRQEDPHKATVDGVLLVVLKELKAIMKRDLNRKMVEVVAFRAFDEWWDKK 900
DPSVPPPGYMPRQEDPHKATVDGVLLVVLKELKAIMKRDLNRKMVEVVAFRAFDEWWDKK
Sbjct: 841 DPSVPPPGYMPRQEDPHKATVDGVLLVVLKELKAIMKRDLNRKMVEVVAFRAFDEWWDKK 900
Query: 901 ERMAKASLTPVKSGEHKDEDRPKPKDRIASCLLESWGKGEGLGYEGLGLGIGLRGAIRLP 960
ERMAKASLTPVKSGEHKDEDRPKPKDRIASCLLESWGKGEGLGYEGLGLGIGLRGAIRLP
Sbjct: 901 ERMAKASLTPVKSGEHKDEDRPKPKDRIASCLLESWGKGEGLGYEGLGLGIGLRGAIRLP 960
Query: 961 SFKVKRKEPPDTTSSGDQKRLRPSTSVDEEDEESERERDRDMADTPCELAKRDPKGVGVR 1020
SFKVKRKEPPDTTSSGDQKRLRPSTSVDEEDEESERERDRDMADTPCELAKRDPKGVGVR
Sbjct: 961 SFKVKRKEPPDTTSSGDQKRLRPSTSVDEEDEESERERDRDMADTPCELAKRDPKGVGVR 1020
Query: 1021 RRPARPLELDSGGEEDEKESLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDESENDDED 1080
RRPARPLELDSGGEEDEKESLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDESENDDED
Sbjct: 1021 RRPARPLELDSGGEEDEKESLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDESENDDED 1080
Query: 1081 TALSEASEKDEGDSDEEETVSIVTSKAEATSSSESSESSEFESSSESSPSSSEDEEEVVA 1140
TALSEASEKDEGDSDEEETVSIVTSKAEATSSSESSESSEFESSSESSPSSSEDEEEVVA
Sbjct: 1081 TALSEASEKDEGDSDEEETVSIVTSKAEATSSSESSESSEFESSSESSPSSSEDEEEVVA 1140
Query: 1141 REEEEEEEEEEMVAEESMASAGPEDFEQDGEEAALAPGAPAVDSLGMEEEVDIETEAVAP 1200
REEEEEEEEEEMVAEESMASAGPEDFEQDGEEAALAPGAPAVDSLGMEEEVDIETEAVAP
Sbjct: 1141 REEEEEEEEEEMVAEESMASAGPEDFEQDGEEAALAPGAPAVDSLGMEEEVDIETEAVAP 1200
Query: 1201 EERPSMLDEPPLPVGVEEPADSREPPEEPGLSQEGAMLLSPEPPAKEVEARPPLSPERAP 1260
EERPSMLDEPPLPVGVEEPADSREPPEEPGLSQEGAMLLSPEPPAKEVEARPPLSPERAP
Sbjct: 1201 EERPSMLDEPPLPVGVEEPADSREPPEEPGLSQEGAMLLSPEPPAKEVEARPPLSPERAP 1260
Query: 1261 EHDLEVEPEPPMMLPLPLQPPLPPPRPPRPPSPPPEPETTDASHPSVPPEPLAEDHPPHT 1320
EHDLEVEPEPPMMLPLPLQPPLPPPRPPRPPSPPPEPETTDASHPSVPPEPLAEDHPPHT
Sbjct: 1261 EHDLEVEPEPPMMLPLPLQPPLPPPRPPRPPSPPPEPETTDASHPSVPPEPLAEDHPPHT 1320
Query: 1321 PGLCGSLAKSQSTETVPATPGGEPPLSGGSSGLSLSSPQVPGSPFSYPAPSPSLSSGGLP 1380
PGLCGSLAKSQSTETVPATPGGEPPLSGGSSGLSLSSPQVPGSPFSYPAPSPSLSSGGLP
Sbjct: 1321 PGLCGSLAKSQSTETVPATPGGEPPLSGGSSGLSLSSPQVPGSPFSYPAPSPSLSSGGLP 1380
Query: 1381 RTPGRDFSFTPTFSEPSGPLLLPVCPLPTGRRDERSGPLASPVLLETGLPLPLPLPLPLP 1440
RTPGRDFSFTPTFSEPSGPLLLPVCPLPTGRRDERSGPLASPVLLETGLPLPLPLPLPLP
Sbjct: 1381 RTPGRDFSFTPTFSEPSGPLLLPVCPLPTGRRDERSGPLASPVLLETGLPLPLPLPLPLP 1440
Query: 1441 LALPAVLRAQARAPTPLPPLLPAPLASCPPPMKRKPGRPRRSPPSMLSLDGPLVRPPAGA 1500
LALPAVLRAQARAPTPLPPLLPAPLASCPPPMKRKPGRPRRSPPSMLSLDGPLVRPPAGA
Sbjct: 1441 LALPAVLRAQARAPTPLPPLLPAPLASCPPPMKRKPGRPRRSPPSMLSLDGPLVRPPAGA 1500
Query: 1501 ALGRELLLLPGQPQTPVFPSTHDPRTVTLDFRNAGIPAPPPPLPPQPPPPPPPPPVEPTK 1560
ALGRELLLLPGQPQTPVFPSTHDPRTVTLDFRNAGIPAPPPPLPPQPPPPPPPPPVEPTK
Sbjct: 1501 ALGRELLLLPGQPQTPVFPSTHDPRTVTLDFRNAGIPAPPPPLPPQPPPPPPPPPVEPTK 1560
Query: 1561 LPFKELDNQWPSEAIPPGPRGRDEVTEEYMELAKSRGPWRRPPKKRHEDLVPPAGSPELS 1620
LPFKELDNQWPSEAIPPGPRGRDEVTEEYMELAKSRGPWRRPPKKRHEDLVPPAGSPELS
Sbjct: 1561 LPFKELDNQWPSEAIPPGPRGRDEVTEEYMELAKSRGPWRRPPKKRHEDLVPPAGSPELS 1620
Query: 1621 PPQPLFRPRSEFEEMTILYDIWNGGIDEEDIRFLCVTYERLLQQDNGMDWLNDTLWVYHP 1680
PPQPLFRPRSEFEEMTILYDIWNGGIDEEDIRFLCVTYERLLQQDNGMDWLNDTLWVYHP
Sbjct: 1621 PPQPLFRPRSEFEEMTILYDIWNGGIDEEDIRFLCVTYERLLQQDNGMDWLNDTLWVYHP 1680
Query: 1681 STSLSSAKKKKRDDGIREHVTGCARSEGFYTIDKKDKLRYLNSSRASTDEPPADTQGMSI 1740
STSLSSAKKKKRDDGIREHVTGCARSEGFYTIDKKDKLRYLNSSRASTDEPPADTQGMSI
Sbjct: 1681 STSLSSAKKKKRDDGIREHVTGCARSEGFYTIDKKDKLRYLNSSRASTDEPPADTQGMSI 1740
Query: 1741 PAQPHASTRAGSERRSEQRRLLSSFTGSCDSDLLKFNQLKFRKKKLKFCKSHIHDWGLFA 1800
PAQPHASTRAGSERRSEQRRLLSSFTGSCDSDLLKFNQLKFRKKKLKFCKSHIHDWGLFA
Sbjct: 1741 PAQPHASTRAGSERRSEQRRLLSSFTGSCDSDLLKFNQLKFRKKKLKFCKSHIHDWGLFA 1800
Query: 1801 MEPIAADEMVIEYVGQNIRQVIADMREKRYEDEGIGSSYMFRVDHDTIIDATKCGNFARF 1860
MEPIAADEMVIEYVGQNIRQVIADMREKRYEDEGIGSSYMFRVDHDTIIDATKCGNFARF
Sbjct: 1801 MEPIAADEMVIEYVGQNIRQVIADMREKRYEDEGIGSSYMFRVDHDTIIDATKCGNFARF 1860
Query: 1861 INHSCNPNCYAKVITVESQKKIVIYSKQHINVNEEITYDYKFPIEDVKIPCLCGSENCRG 1920
INHSCNPNCYAKVITVESQKKIVIYSKQHINVNEEITYDYKFPIEDVKIPCLCGSENCRG
Sbjct: 1861 INHSCNPNCYAKVITVESQKKIVIYSKQHINVNEEITYDYKFPIEDVKIPCLCGSENCRG 1920
Query: 1921 TLN 1923
TLN
Sbjct: 1921 TLN 1923
>gi|55741677 SET domain containing 1A [Homo sapiens]
Length = 1707
Score = 684 bits (1766), Expect = 0.0
Identities = 561/1632 (34%), Positives = 743/1632 (45%), Gaps = 298/1632 (18%)
Query: 19 GPSGERRNHHWRSYKLMIDPAL----KKGHHKLYRYDGQHFSLAMSSNRPVEIVEDPRVV 74
G + + WR+YKL++DPAL ++ K+YRYDG HFS+ S PVE ++DPR
Sbjct: 7 GDGQKAPSFQWRNYKLIVDPALDPALRRPSQKVYRYDGVHFSVNDSKYIPVEDLQDPRC- 65
Query: 75 GIWTKNKELELSVPKFKIDEFYVGPVPPKQVTFAKLNDNIRENFLRDMCKKYGEVEEVEI 134
+ +KN++ L VPKFK+DEFY+G +P K+VTFA+LNDN+RE FL+DMC+KYGEVEEVEI
Sbjct: 66 HVRSKNRDFSLPVPKFKLDEFYIGQIPLKEVTFARLNDNVRETFLKDMCRKYGEVEEVEI 125
Query: 135 LYNPKTKKHLGIAKVVFATVRGAKDAVQHLHSTSVMGNIIHVELDTKGETRMRFYELLVT 194
L +P+T+KHLG+A+V+F + RGAK+ V++LH TSVMGNIIH +LD KG+ RM++YEL+V
Sbjct: 126 LLHPRTRKHLGLARVLFTSTRGAKETVKNLHLTSVMGNIIHAQLDIKGQQRMKYYELIVN 185
Query: 195 GRYTPQTLPVGELDAVSPIVNETLQLSDALKRLKDGGLSAGCGSGSSSVTPNSGGTPFSQ 254
G YTPQT+P G A R + +A +G+++V GTP SQ
Sbjct: 186 GSYTPQTVPTGGKALSEKFQGSGAATETAESRRRSSSDTAAYPAGTTAVGTPGNGTPCSQ 245
Query: 255 DTAYSSCRLDTPNSYG-------QGTPLTPRLGTPFSQDSSYSSRQPTPSYLFSQDPAVT 307
DT++SS R DTP+S+G QGTP T R TP+SQDS+YSS + S
Sbjct: 246 DTSFSSSRQDTPSSFGQFTPQSSQGTPYTSRGSTPYSQDSAYSSSTTSTS---------- 295
Query: 308 FKARRHESKFTDAYNRRHEHHYVHNSPAVTAVA---GATAAFRGSSDLPFGAVGGTGGSS 364
FK RR E+ + DA++RRH ++ A TA+A ATA+ SS + + SS
Sbjct: 296 FKPRRSENSYQDAFSRRHFSASSASTTASTAIAATTAATASSSASSSSLSSSSSSSSSSS 355
Query: 365 GPPFKAQPQDSATF--------AHTP-PPAQAT--PAPGFKSA------FSPYQTPVAHF 407
F++ + + HT PP +AT PG A F P T ++
Sbjct: 356 SSQFRSSDANYPAYYESWNRYQRHTSYPPRRATREEPPGAPFAENTAERFPPSYT--SYL 413
Query: 408 PPPPEEPTATAAFGARDSGEFR--RAPAPPPLPPAEPLAKEKPGTPPGPPPPDTNSMELG 465
PP P PT ++R + APPP PP EP G G P P+ +
Sbjct: 414 PPEPSRPT---------DQDYRPPASEAPPPEPP-EP----GGGGGGGGPSPEREEVRTS 459
Query: 466 GRPTFGWSPEPCDSPGTPTLESSPAGPEKPHDSLDSRIEMLLKEQRTKLLFLREPDSDTE 525
RP SP SP T S P H SLDSRIEMLLKEQR+K FL SDTE
Sbjct: 460 PRPA---SPARSGSPAPETTNESV--PFAQHSSLDSRIEMLLKEQRSKFSFLA---SDTE 511
Query: 526 LQMEGSPISSSSSQLSPLAPFGTNSQPGFRGPTPPSSRPSSTGLEDISPTPLPDSDEDEE 585
+ E S + + P G+ P TPP P+ ED++PT
Sbjct: 512 EEEENSSMVLGARDTGSEVPSGSGHGP----CTPP---PAPANFEDVAPT---------- 554
Query: 586 LDLGLGPRPPPEPGPPDPAGLLSQTAEVALDLVGDRTPTSEKMDEGQQSS----GEDMEI 641
G G EPG T S K + Q+S G+DMEI
Sbjct: 555 ---GSG-----EPG---------------------ATRESPKANGQNQASPCSSGDDMEI 585
Query: 642 SDDEMPSAPITSADCPKPMVVTPGAAAVAAPSVLAPTLPLPPPPGFPPLPPPPPPPPPQP 701
SDD+ +P PP P P PPPPPPPPP P
Sbjct: 586 SDDDRGGSP-------------------------------PPAPTPPQQPPPPPPPPPPP 614
Query: 702 GFPMPPPLPPPPPPPPPAHPAVTVPPPPLPAPPGVPPPPILPPLPPFPPGLFP-VMQVDM 760
PP L P PP PA +PP P PPPP PP PP PP ++ V +++
Sbjct: 615 ----PPYLASLPLGYPPHQPAYLLPP-----RPDGPPPPEYPPPPPPPPHIYDFVNSLEL 665
Query: 761 SHVLGGQWGGMPMSFQMQTQVLSR---LMTGQGACPYPPFMAAAAAAASAGLQFVNLPP- 816
LG QWGGMPMSFQMQTQ+L+R L G+G +A + G F+ PP
Sbjct: 666 MDRLGAQWGGMPMSFQMQTQMLTRLHQLRQGKGLIA----ASAGPPGGAFGEAFLPFPPP 721
Query: 817 ----YRGPFSLSNSG-PGRG------QHWP------PLPKFDPSVPPPGYMPRQED---- 855
Y P++L G GRG H P PLP S PR+E
Sbjct: 722 QEAAYGLPYALYAQGQEGRGAYSREAYHLPMPMAAEPLPSSSVSGEEARLPPREEAELAE 781
Query: 856 ----PHKATVDGVLLVVLKELKAIMKRDLNRKMVEVVAFRAFDEWWDKKERMAKASLTPV 911
P TV VL ++++E+K+IM+RDLNRKMVE VAF AFD+WW+ KE AK
Sbjct: 782 GKTLPTAGTVGRVLAMLVQEMKSIMQRDLNRKMVENVAFGAFDQWWESKEEKAKPFQNAA 841
Query: 912 KSGEHKDEDRPKPKDRIASCL-LESWGKGEG-LGYEGLGLGIGLRGAIRLPSFKVKRKEP 969
K + K+ED+ K K + L L W K G G E G GLRGA+RLPSFKVKRKEP
Sbjct: 842 KQ-QAKEEDKEKTKLKEPGLLSLVDWAKSGGTTGIEAFAFGSGLRGALRLPSFKVKRKEP 900
Query: 970 PDTTSSGDQKRLRPSTSVDEEDEESERERDRDMADTP-CELAKRDPKGVGVRRRPARPLE 1028
+ + + ++KR RPST +E++++ E+E++ P + KRD + + + +
Sbjct: 901 SEISEASEEKRPRPSTPAEEDEDDPEQEKEAGEPGRPGTKPPKRDEERGKTQGKHRKSFA 960
Query: 1029 LDSGGEEDEKESLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDESENDDEDTALSEASE 1088
LDS GEE +ES SE+ E E++EE EE+E+ E+ D + + S+ +DE+ S++S
Sbjct: 961 LDSEGEEASQESSSEKDE--EDDEEDEEDEDREEAVDTTKKETEVSDGEDEE---SDSSS 1015
Query: 1089 KDE--GDSDEEETVSIVTSKAEATSSSESSESSEFESSSESSPSSSEDEEEVVAREEEEE 1146
K DSD E TS +E++SSS SS SS SSS SS SSSE E+
Sbjct: 1016 KCSLYADSDGEND---STSDSESSSSSSSSSSSSSSSSSSSSSSSSE--------SSSED 1064
Query: 1147 EEEEEMVAEESMASAGPEDFEQDGEEAALAPGAPAVDSLGMEEEVDIETEAVAPEERPSM 1206
EEEEE A AS P EV + T
Sbjct: 1065 EEEEERPAALPSASPPP-------------------------REVPVPT----------- 1088
Query: 1207 LDEPPLPVGVEEPADSREPPEEPGLSQEGAMLLSPEPPAKEVEARPPLSPERAPEHDLEV 1266
P PV V P P P QE SP PA E PP +P R
Sbjct: 1089 ----PAPVEVPVPERVAGSPVTPLPEQEA----SPARPAGPTEESPPSAPLR-------- 1132
Query: 1267 EPEPPMMLPLPLQPPLPPPRPPRPPSPPPEPETTDASHPSVPPEPLAEDHPPHTPGLCGS 1326
PEPP P P P P P P PPP+ S ++ P A + PP TP
Sbjct: 1133 PPEPPAGPPAPAPRPDERPSSPIPLLPPPKKRRKTVSFSAIEVVP-APEPPPATP----- 1186
Query: 1327 LAKSQSTETVPATPGGEPPLSGGSSGLSLSSPQVPGSPFSYPAPSP-SLSSGGLPRTPGR 1385
P P G+ + +P S P +S GG R GR
Sbjct: 1187 ----------PQAKFPGPASRKAPRGVERTIRNLPLDHASLVKSWPEEVSRGGRSRAGGR 1236
Query: 1386 DFSFTPTFSEPSGPLLLPV---CPLPTGRRDERSGP-LASPVLLETGLPLPLPLPLPLPL 1441
+EP + L V L RR + P + ET P PL +
Sbjct: 1237 GRLTEEEEAEPGTEVDLAVLADLALTPARRGLPALPAVEDSEATETSDEAERPRPLLSHI 1296
Query: 1442 ALPAVLRAQARAPTPLPPLLPAPLASCPPPMKRKPGRPRRSPPSMLSLDGPLVRP----- 1496
L + P P L P P + P P ++ + +P
Sbjct: 1297 LLEHNYALAVKPTPPAPALRPPEPVPAPAALFSSPADEVLEAPEVVVAEAEEPKPQQLQQ 1356
Query: 1497 --PAGAALGRELLLLPGQPQTPVFPSTHDPRTVTLDFRNAGIPAPPPPLPPQPPPPPPPP 1554
G G E G+ + + R + + P PPPPPPPP
Sbjct: 1357 QREEGEEEGEE----EGEEEEEESSDSSSSSDGEGALRRRSLRSHARRRRPPPPPPPPPP 1412
Query: 1555 PVEPTKLPFKEL 1566
+ F+++
Sbjct: 1413 RAYEPRSEFEQM 1424
Score = 486 bits (1251), Expect = e-137
Identities = 348/934 (37%), Positives = 445/934 (47%), Gaps = 169/934 (18%)
Query: 1037 EKESLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDESENDDEDTALSEASEKDEGDSDE 1096
+++ SE E++EE+ EED+DD + EK+ G+
Sbjct: 896 KRKEPSEISEASEEKRPRPSTPAEEDEDDPEQ-------------------EKEAGEPGR 936
Query: 1097 EETVSIVTSKAEATSSSESSESSEFESSSESSPSSSEDEEEVVAREEEEEEEEEEMVAEE 1156
T + + + +S +S E + S E++ EE++EE+EE+ EE
Sbjct: 937 PGTKPPKRDEERGKTQGKHRKSFALDSEGEEASQESSSEKD----EEDDEEDEEDEDREE 992
Query: 1157 SMASAGPEDFEQDGEEAALAPGAPAVDSLGMEEEVDIETEAVAPEERPSMLDEPPLPVGV 1216
++ + E DGE+ + + + + D E ++ + E S
Sbjct: 993 AVDTTKKETEVSDGEDEE----SDSSSKCSLYADSDGENDSTSDSESSSS---------- 1038
Query: 1217 EEPADSREPPEEPGLSQEGAMLLSPEPPAKEVEARPPLSPERAPEHDLEVEPEPPMMLPL 1276
+ S S + +E E RP P +P PP +P+
Sbjct: 1039 ---SSSSSSSSSSSSSSSSSSSSESSSEDEEEEERPAALPSASP---------PPREVPV 1086
Query: 1277 PLQPPLPPPRPPRPPSPPPEPETTDASHPSVPPEPLAEDHPPHTPGLCGSLAKSQSTETV 1336
P P+ P P R P P + P+ P P E+ PP P
Sbjct: 1087 PTPAPVEVPVPERVAGSPVTPLPEQEASPARPAGP-TEESPPSAP--------------- 1130
Query: 1337 PATPGGEPPLSGGSSGLSLSSPQVPGSPFSYPAPSPSLSSGGLPRTPGRDFSFTPTFSEP 1396
L P+ P P PAP+P P
Sbjct: 1131 ------------------LRPPEPPAGP---PAPAPRPDE------------------RP 1151
Query: 1397 SGPLLLPVCPLPTGRRDERSGPLASPVLLETGLPLPLPLPLPLPLAL---PAVLRAQARA 1453
S P+ P+ P P RR S V P P P P P A PA +A
Sbjct: 1152 SSPI--PLLPPPKKRRKTVSFSAIEVV------PAPEPPPATPPQAKFPGPASRKAPRGV 1203
Query: 1454 PTPLP--PLLPAPLASCPPPMKRKPGRPRRSPPSMLSLDGPLVR-PPAGAALGRELLLLP 1510
+ PL A L P + GR R L+ + A+ +L L P
Sbjct: 1204 ERTIRNLPLDHASLVKSWPEEVSRGGRSRAGGRGRLTEEEEAEPGTEVDLAVLADLALTP 1263
Query: 1511 GQPQTPVFPSTHD------------PRT----VTLDFRNAGIPAPPPPLPPQPPPPPPPP 1554
+ P P+ D PR + L+ A P PP P PP P P
Sbjct: 1264 ARRGLPALPAVEDSEATETSDEAERPRPLLSHILLEHNYALAVKPTPPAPALRPPEPVPA 1323
Query: 1555 PVEPTKLPFKEL---DNQWPSEAIPPGPR------------GRDEVTEEYMELAKS---- 1595
P P E+ +EA P P+ G +E EE E + S
Sbjct: 1324 PAALFSSPADEVLEAPEVVVAEAEEPKPQQLQQQREEGEEEGEEEGEEEEEESSDSSSSS 1383
Query: 1596 --RGPWRRPPKKRHEDLVPPAGSPELSPPQPLFRPRSEFEEMTILYDIWNGGIDEEDIRF 1653
G RR + H P P PP+ + PRSEFE+MTILYDIWN G+D ED+ +
Sbjct: 1384 DGEGALRRRSLRSHARRRRPPPPPPPPPPRA-YEPRSEFEQMTILYDIWNSGLDSEDMSY 1442
Query: 1654 LCVTYERLLQQDNGMDWLNDTLWVYHPSTSLSSAKKKKR-DDGIREHVTGCARSEGFYTI 1712
L +TYERLLQQ +G DWLNDT WV+H T+L++ K+K+R DG REH TG ARSEG+Y I
Sbjct: 1443 LRLTYERLLQQTSGADWLNDTHWVHHTITNLTTPKRKRRPQDGPREHQTGSARSEGYYPI 1502
Query: 1713 DKKDKLRYLNSSRASTDE-PPADTQGMSIPAQPHASTRAGSERRSEQRRLLSSFTGSC-- 1769
KK+K +YL+ S + DTQG + R SERRSEQRRLLS+ S
Sbjct: 1503 SKKEKDKYLDVCPVSARQLEGVDTQG---------TNRVLSERRSEQRRLLSAIGTSAIM 1553
Query: 1770 DSDLLKFNQLKFRKKKLKFCKSHIHDWGLFAMEPIAADEMVIEYVGQNIRQVIADMREKR 1829
DSDLLK NQLKFRKKKL+F +S IH+WGLFAMEPIAADEMVIEYVGQNIRQ++ADMREKR
Sbjct: 1554 DSDLLKLNQLKFRKKKLRFGRSRIHEWGLFAMEPIAADEMVIEYVGQNIRQMVADMREKR 1613
Query: 1830 YEDEGIGSSYMFRVDHDTIIDATKCGNFARFINHSCNPNCYAKVITVESQKKIVIYSKQH 1889
Y EGIGSSY+FRVDHDTIIDATKCGN ARFINH C PNCYAKVIT+ESQKKIVIYSKQ
Sbjct: 1614 YVQEGIGSSYLFRVDHDTIIDATKCGNLARFINHCCTPNCYAKVITIESQKKIVIYSKQP 1673
Query: 1890 INVNEEITYDYKFPIEDVKIPCLCGSENCRGTLN 1923
I V+EEITYDYKFP+ED KIPCLCG+E+CRG+LN
Sbjct: 1674 IGVDEEITYDYKFPLEDNKIPCLCGTESCRGSLN 1707
Score = 59.3 bits (142), Expect = 4e-08
Identities = 84/314 (26%), Positives = 102/314 (32%), Gaps = 71/314 (22%)
Query: 1283 PPPRPPR--PPSPPPEPETTDASHPS----VPPEPLAEDHPPHTPGLCGSLAKSQSTETV 1336
PP R R PP P T + PS +PPEP + P S++
Sbjct: 383 PPRRATREEPPGAPFAENTAERFPPSYTSYLPPEPSRPTDQDYRP------PASEAPPPE 436
Query: 1337 PATPGGEPPLSGGSSGLSLSSPQVPGSPFSYPAPSPSLSSGGLPRTPGRDFSFTPTFSEP 1396
P PGG GG G S +V SP PA SP+ S P T F S
Sbjct: 437 PPEPGG----GGGGGGPSPEREEVRTSP--RPA-SPARSGSPAPETTNESVPFAQHSSLD 489
Query: 1397 SGPLLL--------PVCPLPTGRRDERSGPLASPVLLETGLPLPLPLPLPLPLALPAVLR 1448
S +L T +E S + +TG +P
Sbjct: 490 SRIEMLLKEQRSKFSFLASDTEEEEENSSMVLGA--RDTGSEVP---------------S 532
Query: 1449 AQARAPTPLPPLLPAPLASCPPPMKRKPGRPRRSPPSMLSLDGPLVRPPAGAALGRELLL 1508
P PP PA P +PG R SP +
Sbjct: 533 GSGHGPCTPPPA-PANFEDVAPTGSGEPGATRESPKAN---------------------- 569
Query: 1509 LPGQPQTPVFPSTHDPRTVTLDFRNAGIPAPPPPLPPQPPPPPPPPPVE-PTKLPFKELD 1567
GQ Q S D D + PAP PP P PPPPPPPPP LP
Sbjct: 570 --GQNQASPCSSGDDMEISDDDRGGSPPPAPTPPQQPPPPPPPPPPPPPYLASLPLGYPP 627
Query: 1568 NQWPSEAIPPGPRG 1581
+Q P+ +PP P G
Sbjct: 628 HQ-PAYLLPPRPDG 640
Score = 41.2 bits (95), Expect = 0.010
Identities = 133/560 (23%), Positives = 180/560 (32%), Gaps = 87/560 (15%)
Query: 1074 SENDDEDTALSEASEKDEGDSDEEETVSIVTSKAEATSSSESSESSEFESSSESSPSSSE 1133
SEN +D A S S T T+ A A+SS+ SS S SSS SS SS
Sbjct: 301 SENSYQD-AFSRRHFSASSASTTASTAIAATTAATASSSASSSSLSSSSSSSSSSSSSQF 359
Query: 1134 DEEEVVAREEEEEEEEEEMVAEESMASAGPEDFEQDGEEAALAPGAPAVDSLGMEEEVDI 1193
+ E + A E+ PGAP ++
Sbjct: 360 RSSDANYPAYYESWNRYQRHTSYPPRRATREE----------PPGAPFAENTA------- 402
Query: 1194 ETEAVAPEERPSMLDEPPLPVGVE-EPADSREPPEEPGLSQEGAMLLSPEPPAKEVEARP 1252
E P + EP P + P S PP EP PEP P
Sbjct: 403 --ERFPPSYTSYLPPEPSRPTDQDYRPPASEAPPPEP-----------PEPGGGGGGGGP 449
Query: 1253 PLSPERAPEHDLEVEPEPPMMLPLPLQPPLPPPRPPRPPSPPPEPETTD---ASHPSVPP 1309
SPER EV P P P R SP PE A H S+
Sbjct: 450 --SPERE-----EVRTSPR------------PASPARSGSPAPETTNESVPFAQHSSLDS 490
Query: 1310 --EPLAEDHPPHTPGLCGSLAKSQ--STETVPATPGGEPPLSGGSSGLSLSSPQVPGSPF 1365
E L ++ L + + S+ + A G SG G + P P + F
Sbjct: 491 RIEMLLKEQRSKFSFLASDTEEEEENSSMVLGARDTGSEVPSGSGHG-PCTPPPAPAN-F 548
Query: 1366 SYPAPSPSLSSGGLPRTPGRDFSFTPTFSEPSGPLLLPVCPLPTGRRDERSGPLASPVLL 1425
AP+ S G +P + + + + D+R G SP
Sbjct: 549 EDVAPTGSGEPGATRESPKANGQNQASPCSSGDDMEIS--------DDDRGG---SPPPA 597
Query: 1426 ETGLPLPLPLPLPLPLALPAVLRAQARAPTPLPPLLPAPLASCPPPMKRKPGRPRRSPPS 1485
T P P P P P P + P P L P PPP + P P PP
Sbjct: 598 PTPPQQPPPPPPPPPPPPPYLASLPLGYPPHQPAYLLPPRPDGPPPPEYPP--PPPPPPH 655
Query: 1486 MLSLDGPL-VRPPAGAALGRELLLLPGQPQTPVFPSTHDPRT-VTLDFRNAGIPAPPPPL 1543
+ L + GA G + + Q QT + H R L +AG PP
Sbjct: 656 IYDFVNSLELMDRLGAQWGG--MPMSFQMQTQMLTRLHQLRQGKGLIAASAG---PPGGA 710
Query: 1544 PPQPPPPPPPPPVEPTKLPF------KELDNQWPSEAIP-PGPRGRDEVTEEYMELAKSR 1596
+ P PPP LP+ +E + EA P P + + + ++R
Sbjct: 711 FGEAFLPFPPPQEAAYGLPYALYAQGQEGRGAYSREAYHLPMPMAAEPLPSSSVSGEEAR 770
Query: 1597 GPWRRPPKKRHEDLVPPAGS 1616
P R + +P AG+
Sbjct: 771 LPPREEAELAEGKTLPTAGT 790
>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
sapiens]
Length = 2715
Score = 178 bits (452), Expect = 4e-44
Identities = 247/855 (28%), Positives = 327/855 (38%), Gaps = 217/855 (25%)
Query: 1146 EEEEEEMVAEESMASA--GPEDFEQD-------------------GEEAALAPGAPAVDS 1184
E +EE+VA +M S+ GP D ++ G + PGAP ++
Sbjct: 2001 EPFQEEIVAAGAMGSSHGGPGDSSEEESSPTSRYIHFPVTVVSAPGLAPSATPGAPRIEQ 2060
Query: 1185 L-GMEEEVDIETEAVAPEERPSMLDEPPLPVGVEEPADSREPPEEPGLSQEGAMLLSPEP 1243
L G+++ D E EAV ++P PP PG+ + G + + +
Sbjct: 2061 LDGVDDGTDSEAEAV------------------QQPRGQGTPPSGPGVVRAGVLGAAGD- 2101
Query: 1244 PAKEVEARPPLSPERAPEHDLEVEPEPPMMLPLPLQPPLPPPRPPRPPSPPPEPETTDAS 1303
ARPP E P ++ + L P PR S PP P + S
Sbjct: 2102 -----RARPP---EDLPSEIVD-------FVLKNLGGPGDGGAGPREESLPPAPPLANGS 2146
Query: 1304 HPSVPPEPLAEDHPPHTPGLCGSLAKSQSTETVPATPGGEPPLSGGSSGLSLSSPQVPGS 1363
PS GL S A T T PG G LSL P
Sbjct: 2147 QPS--------------QGLTASPA--DPTRTFAWLPGAP-----GVRVLSLGPAPEP-- 2183
Query: 1364 PFSYPAPSPSLSSGGLPRTPGRDFSFTPTFSEPSGPLLLPVCPLPTGRRDERSGPLASPV 1423
P P+ S L G+ F EP P + PLP P SP
Sbjct: 2184 ------PKPATSKIILVNKLGQVFVKMAGEGEPVPPPVKQP-PLP---------PTISPT 2227
Query: 1424 LLETGLPLPLPLPLPLPLALPAVLRAQARAPTPLPPLLPAPLASCPPPMKRKPGRPRRSP 1483
T LP P PL LP V+ AP P PP L L+S P R+ R +R
Sbjct: 2228 A-PTSWTLP---PGPLLGVLP-VVGVVRPAPPPPPPPLTLVLSSGPASPPRQAIRVKRV- 2281
Query: 1484 PSMLSLDGPLVRPPAGAA-LGRELLLLPGQPQTPVFPSTHDPR------TV--TLDFRNA 1534
S S P PP A L + PQ P S R TV LD
Sbjct: 2282 -STFSGRSPPAPPPYKAPRLDEDGEASEDTPQVPGLGSGGFSRVRMKTPTVRGVLDLDRP 2340
Query: 1535 GIPA---PPPPLPPQPPPPPPP---PPVEPTKLPFKELDNQW--------PSEAIPPGPR 1580
G PA P PL + P P P PP P P L++QW SE PP P
Sbjct: 2341 GEPAGEESPGPLQERSPLLPLPEDGPPQVPDGPPDLLLESQWHHYSGEASSSEEEPPSPD 2400
Query: 1581 GRDEVTEEYMELAKSRGPWRRPPKKRHEDLVPPAGSPELSPPQPLFRPRSEFEEMTILYD 1640
++ ++ P R P R E S E + +R E +
Sbjct: 2401 DKE-----------NQAPKRTGPHLRFEISSEDGFSVEAESLEGAWRTLIEKVQEA---- 2445
Query: 1641 IWNGGIDEEDIRFLCVTYERLLQQDNGMDWLNDTLWVYHPSTSLSSAKKKKRDDGIREHV 1700
G + F ++ RL L ++H + + E +
Sbjct: 2446 --RGHARLRHLSFSGMSGARL-------------LGIHHDAVIF-----------LAEQL 2479
Query: 1701 TGCARSEGFYTIDKKDKLRYLNSSRASTDEPPADTQGMSIPAQPHASTRAGSERR----- 1755
G R + + K RY + +EPP + PH + RA R
Sbjct: 2480 PGAQRCQHY-------KFRY-HQQGEGQEEPPLN---------PHGAARAEVYLRKCTFD 2522
Query: 1756 -----SEQRRLLSSFTGSCDSD-------------------LLKFNQL-KFRKKKLKFCK 1790
+ Q R+L +CD + ++F L K K+ + +
Sbjct: 2523 MFNFLASQHRVLPE-GATCDEEEDEVQLRSTRRATSLELPMAMRFRHLKKTSKEAVGVYR 2581
Query: 1791 SHIHDWGLFAMEPIAADEMVIEYVGQNIRQVIADMREKRYEDEGIGSSYMFRVDHDTIID 1850
S IH GLF I A EMVIEY G IR V+ D REK Y+ +GIG YMFR+D ++D
Sbjct: 2582 SAIHGRGLFCKRNIDAGEMVIEYSGIVIRSVLTDKREKFYDGKGIG-CYMFRMDDFDVVD 2640
Query: 1851 ATKCGNFARFINHSCNPNCYAKVITVESQKKIVIYSKQHINVNEEITYDYKFPIEDV--K 1908
AT GN ARFINHSC PNC+++VI VE QK IVI++ + I EE+TYDYKFPIED K
Sbjct: 2641 ATMHGNAARFINHSCEPNCFSRVIHVEGQKHIVIFALRRILRGEELTYDYKFPIEDASNK 2700
Query: 1909 IPCLCGSENCRGTLN 1923
+PC CG++ CR LN
Sbjct: 2701 LPCNCGAKRCRRFLN 2715
Score = 92.0 bits (227), Expect = 5e-18
Identities = 112/417 (26%), Positives = 151/417 (36%), Gaps = 110/417 (26%)
Query: 1217 EEPADSREPPEEPGLSQEGAMLLSPEPPAKEVEARPPLSPERAPEHDLEVEPEPPMMLPL 1276
EE + E +E +E A+ P A++ EA+ P P P P PP
Sbjct: 366 EEKKEEEEKDKEGEEKEERAVAEEMMPAAEKEEAKLPPPPLTPPA------PSPP----- 414
Query: 1277 PLQPPLPPPR--PPRPPSPPPEPETTDASHPSVPPEPLAEDH----PPHTPGLCGSLAKS 1330
PPLPPP PP P PPP P + PS PP P E+ PP P C S
Sbjct: 415 ---PPLPPPSTSPPPPLCPPPPPPVSPPPLPSPPPPPAQEEQEESPPPVVPATC-----S 466
Query: 1331 QSTETVPATPGGEPPLSGGSSGLSLSSPQVPGSPFSYPAPSPSLSSGGLPRTPGRDFSFT 1390
+ P TP +G +SP P P+PS ++GG P +
Sbjct: 467 RKRGRPPLTPSQRAEREAARAGPEGTSP---------PTPTPSTATGGPPEDSPTVAPKS 517
Query: 1391 PTFSEPSGPLLLPVCPLPTGRRDERSGPLASPVLLETGLPLPLPLPLPLPLALPAVLRAQ 1450
TF + ++PV + R + +P P P P + + VLR
Sbjct: 518 TTFLKNIRQFIMPVVSARSSR------VIKTPRRFMDEDP-----PKPPKVEVSPVLRPP 566
Query: 1451 ARAPTPLPPLLPAPLASCPPPMKRKPGRPRRSPPSMLSLDGPLVRPPAGAALGRELLLLP 1510
P+P PAP+ S P R P +PPS P+ P ++ RE
Sbjct: 567 ITTSPPVPQE-PAPVPSPP----RAP-----TPPST-----PVPLPEKRRSILRE----- 606
Query: 1511 GQPQTPVFPSTHDPRTVTLDFRNAGIPAPPPPLPPQPPPPPPPPPVEPTKLPFKELDNQW 1570
P F T R +P PPP PP P P PPP P ++ P Q+
Sbjct: 607 -----PTFRWTSLTRE---------LPPPPPAPPPPPAPSPPPAPATSSRRPLLLRAPQF 652
Query: 1571 -PSEAIPPGPRGRDEVTEEYMELAKSRGPWRRPPKKRHEDLV--PPAGSPELSPPQP 1624
PSEA K +E ++ PP G+PE P+P
Sbjct: 653 TPSEA----------------------------HLKIYESVLTPPPLGAPEAPEPEP 681
Score = 83.2 bits (204), Expect = 2e-15
Identities = 121/464 (26%), Positives = 163/464 (35%), Gaps = 77/464 (16%)
Query: 1043 EEQESTEEEEEAEEEEEEEDDDDDDSDDRDESEN-----DDEDTALSEASEKDEGDSDEE 1097
++++ ++EEE ++EEEE+D + ++ ++R +E + E+ L S
Sbjct: 356 KQEQKLDDEEEEKKEEEEKDKEGEEKEERAVAEEMMPAAEKEEAKLPPPPLTPPAPSPPP 415
Query: 1098 ETVSIVTSKAEATSSSESSESSEFESSSESSPSSSEDEEE--------VVAREEEEEEEE 1149
TS S S P + E++EE +R+
Sbjct: 416 PLPPPSTSPPPPLCPPPPPPVSPPPLPSPPPPPAQEEQEESPPPVVPATCSRKRGRPPLT 475
Query: 1150 EEMVAEESMASAGPEDFEQDGEEAALAPGAPAVDSLGMEEE---------------VDIE 1194
AE A AGPE + A G P DS + + V
Sbjct: 476 PSQRAEREAARAGPEGTSPPTPTPSTATGGPPEDSPTVAPKSTTFLKNIRQFIMPVVSAR 535
Query: 1195 TEAVAPEERPSMLDEPPLPVGVEEPADSREP-PEEPGLSQEGAMLLSPEPPAKEVEARPP 1253
+ V R M ++PP P VE R P P + QE A + P PP PP
Sbjct: 536 SSRVIKTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAPV--PSPPRAPT---PP 590
Query: 1254 LSPERAPEHDLEVEPEPPM---MLPLPLQPPLPPPRPPRPPSPPPEPETTDASHPSVPPE 1310
+P PE + EP L L PP P P PP PSPPP P T+
Sbjct: 591 STPVPLPEKRRSILREPTFRWTSLTRELPPPPPAPPPPPAPSPPPAPATSSR-------R 643
Query: 1311 PLAEDHPPHTPGLCGSLAKSQSTETVPATPGGEPPLSGGSSGLSLSSPQVPGSPFSYPAP 1370
PL P TP S A + E+V TP PPL P +P P P
Sbjct: 644 PLLLRAPQFTP----SEAHLKIYESV-LTP---PPLG------------APEAPEPEPPP 683
Query: 1371 SPSLSSGGLPRTPGRDFSFTPTFSEPSGPLLLPVCPLPTGRRDERSGPLASPVLLETGLP 1430
+ + PR GR + S P PV P G A L G
Sbjct: 684 ADDSPAEPEPRAVGRT-------NHLSLPRFAPVVTTPVKAEVSPHGAPA----LSNGPQ 732
Query: 1431 LPLPLPLPLPLALPAVLRAQARAPTPLPPLLPAPLASCPPPMKR 1474
L PL AL L QA P P P L P P PP+++
Sbjct: 733 TQAQLLQPLQ-ALQTQLLPQA-LPPPQPQLQPPPSPQQMPPLEK 774
Score = 75.9 bits (185), Expect = 4e-13
Identities = 38/71 (53%), Positives = 41/71 (57%), Gaps = 17/71 (23%)
Query: 681 LPPPPGFPPLPPPPPPPPPQPGFPMPPPLPPPPPPPPPAHPAVTVPPPPLPAPPGVP--- 737
LPPPP PP P PPPP PP P PPPL PPPPPP V PPPLP+PP P
Sbjct: 401 LPPPPLTPPAPSPPPPLPP-PSTSPPPPLCPPPPPP--------VSPPPLPSPPPPPAQE 451
Query: 738 -----PPPILP 743
PPP++P
Sbjct: 452 EQEESPPPVVP 462
Score = 73.2 bits (178), Expect = 2e-12
Identities = 45/113 (39%), Positives = 57/113 (50%), Gaps = 16/113 (14%)
Query: 620 DRTPTSEKMDEGQQSSGEDMEISDDEMPSAPITSADCPKPMVVTPGAAAVAAPSVLAPTL 679
++ EK EG++ E+ ++++ MP+A A P P + P APS P
Sbjct: 367 EKKEEEEKDKEGEEK--EERAVAEEMMPAAEKEEAKLPPPPLTPP------APS---PPP 415
Query: 680 PLPPPPGFPPLPPPPPPPPPQPGFPMPPPLPPPPPPPPPAHPAVTVPPPPLPA 732
PLPPP PP P PPPPPP PPPLP PPPPP PPP +PA
Sbjct: 416 PLPPPSTSPPPPLCPPPPPPVS----PPPLPS-PPPPPAQEEQEESPPPVVPA 463
Score = 67.4 bits (163), Expect = 1e-10
Identities = 130/527 (24%), Positives = 177/527 (33%), Gaps = 106/527 (20%)
Query: 389 PAPGFKSAFSPYQTPVAH--FPPPPEEPTATAAFGARDSGEFRRAPAPPPLPPAEPLAKE 446
P+PG S+ + + V FP PP + AP PPP A P K
Sbjct: 1886 PSPGSPSSLTHHIPTVGDPDFPAPPRRSRRPSPL----------APRPPPSRWASPPLKT 1935
Query: 447 KPGTPPGPPPPDTNSMELGGRPTFGWSPEPCDSPGTPTLESSPAGPEKPHDSLDSRIEML 506
P PP ++ PT G P +P P E GP+ + S +
Sbjct: 1936 SPQLRVPPPTSVVTALT----PTSGELAPPGPAPSPPPPED--LGPDFEDMEVVSGLSAA 1989
Query: 507 LKEQRTKLLFLREPDSDTEL------QMEGSPISSSSSQLSPLA-----PFGTNSQPGFR 555
+ LL EP + + G P SS + SP + P S PG
Sbjct: 1990 DLDFAASLLGT-EPFQEEIVAAGAMGSSHGGPGDSSEEESSPTSRYIHFPVTVVSAPGLA 2048
Query: 556 GPTPPSSRPSSTGLEDISPTPLPDSDEDEELDLGLGPRPPPEPGPPDPAGLLSQTAEVAL 615
PS+ P + +E + E E + G PP AG+L + A
Sbjct: 2049 ----PSATPGAPRIEQLDGVDDGTDSEAEAVQQPRGQGTPPSGPGVVRAGVLGAAGDRAR 2104
Query: 616 ---DLVGDRTPTSEKMDEGQQSSGEDMEISDDEMPSAPITSADCPKPMVVTPGAAAVAAP 672
DL + K G G ++ +P AP P P A+P
Sbjct: 2105 PPEDLPSEIVDFVLKNLGGPGDGGAGPR--EESLPPAP------PLANGSQPSQGLTASP 2156
Query: 673 SVLAPTLP-LPPPPGFPPLPPPPPPPPPQP---------------------GFPMPPPLP 710
+ T LP PG L P P PP+P G P+PPP+
Sbjct: 2157 ADPTRTFAWLPGAPGVRVLSLGPAPEPPKPATSKIILVNKLGQVFVKMAGEGEPVPPPVK 2216
Query: 711 PPPPPPPP-----AHPAVTVPPPPLPAPPGVPPPPILPPLPPFPPGLFPVMQVDMSHVLG 765
PP PP A + T+PP PL +P ++ P PP PP P + + +S
Sbjct: 2217 Q--PPLPPTISPTAPTSWTLPPGPLLGV--LPVVGVVRPAPPPPP---PPLTLVLS---- 2265
Query: 766 GQWGGMPMSFQMQTQVLSRLMTGQGACP--YPPFMA--------------AAAAAASAGL 809
P S Q + R+ T G P PP+ A S G
Sbjct: 2266 ----SGPASPPRQAIRVKRVSTFSGRSPPAPPPYKAPRLDEDGEASEDTPQVPGLGSGGF 2321
Query: 810 QFVNL--PPYRGPFSLSNSGPGRGQHWP-PLPKFDPSVPPPGYMPRQ 853
V + P RG L G G+ P PL + P +P P P Q
Sbjct: 2322 SRVRMKTPTVRGVLDLDRPGEPAGEESPGPLQERSPLLPLPEDGPPQ 2368
Score = 67.0 bits (162), Expect = 2e-10
Identities = 103/408 (25%), Positives = 137/408 (33%), Gaps = 87/408 (21%)
Query: 379 AHTPPPAQATPAPGFKSAFSPYQT----PVAHFPPPPEEPTATAAFGARDSGEFRRAPAP 434
A PPP PAP P T P+ PPPP P P+P
Sbjct: 399 AKLPPPPLTPPAPSPPPPLPPPSTSPPPPLCPPPPPPVSPPPL--------------PSP 444
Query: 435 PPLPPAEPLAKEKPGTPPGPP---------PPDTNSMELGGRPTFGWSPEPCDSPGTPTL 485
PP PPA+ +E P PP P PP T S R PE SP TPT
Sbjct: 445 PP-PPAQEEQEESP--PPVVPATCSRKRGRPPLTPSQR-AEREAARAGPEGT-SPPTPTP 499
Query: 486 ESSPAGPEKPHDSLDSRIEMLLKEQRTKLLFLREPDSDTELQ-----MEGSPISSSSSQL 540
++ GP + ++ + LK R ++ + S ++ M+ P ++
Sbjct: 500 STATGGPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPRRFMDEDPPKPPKVEV 559
Query: 541 SP-LAPFGTNSQPGFRGPTPPSSRPSSTGLEDISPTPLPDSDED---------EELDLGL 590
SP L P T S P + P P S P + +P PLP+ L L
Sbjct: 560 SPVLRPPITTSPPVPQEPAPVPSPPRAP-TPPSTPVPLPEKRRSILREPTFRWTSLTREL 618
Query: 591 GPRPPPEPGPPDPAGLLSQTAEVALDLVGDRTPTSEKMDEGQQSSGEDMEISDDEMPSAP 650
P PP P PP P+ R P + + S ++I + + P
Sbjct: 619 PPPPPAPPPPPAPS-------PPPAPATSSRRPLLLRAPQFTPSEAH-LKIYESVLTPPP 670
Query: 651 ITSADCPKP-------MVVTPGAAAVA----------APSVLAPTLPLPPPPGFPPLPPP 693
+ + + P+P P AV AP V P P G P L
Sbjct: 671 LGAPEAPEPEPPPADDSPAEPEPRAVGRTNHLSLPRFAPVVTTPVKAEVSPHGAPALSNG 730
Query: 694 PP-------PPPPQPGFPMPPPLPPPPPPPPPAHPAVTVPPPPLPAPP 734
P P +P LPPP P P PP P PP
Sbjct: 731 PQTQAQLLQPLQALQTQLLPQALPPPQPQLQP-------PPSPQQMPP 771
Score = 65.5 bits (158), Expect = 5e-10
Identities = 131/538 (24%), Positives = 173/538 (32%), Gaps = 130/538 (24%)
Query: 399 PYQTPVAHFPPPPEEPTATAAFGARDSGEFRRAPAPPPLPPAEPLAKEKPGTPPGPPPPD 458
P TP A PPPP P +T+ PPPL P P P P PPPP
Sbjct: 404 PPLTPPAPSPPPPLPPPSTSP--------------PPPLCPPPPPPVSPPPLPSPPPPPA 449
Query: 459 TNSMELGGRPTFGWSPEPCDSP-GTPTL--------ESSPAGPEKPHDSLDSRIEMLLKE 509
E P P C G P L E++ AGPE
Sbjct: 450 QEEQEESPPPVV---PATCSRKRGRPPLTPSQRAEREAARAGPEGT-------------- 492
Query: 510 QRTKLLFLREPDSDTELQMEGSPISSSSSQLSPLAPFGTNSQPGFRG-PTPPSSRPSSTG 568
P + T G P S + +AP T R P S SS
Sbjct: 493 ---------SPPTPTPSTATGGPPEDSPT----VAPKSTTFLKNIRQFIMPVVSARSSRV 539
Query: 569 LEDISPTPLPDSDEDEELDLGLGP--RPPPEPGPPDPAGLLSQTAEVALDLVGDRTPTSE 626
++ +P D D + + + P RPP PP P E A R PT
Sbjct: 540 IK--TPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQ-------EPAPVPSPPRAPTP- 589
Query: 627 KMDEGQQSSGEDMEISDDEMPSAPITSADCPKPMVVTPGAAAVAAPSVLAPTLPLPPPPG 686
PS P+ + + ++ P + L P P PPPP
Sbjct: 590 --------------------PSTPVPLPEKRRSILREPTFRWTSLTRELPPPPPAPPPPP 629
Query: 687 FPPLPPPPPPPPPQPGFPMPPPLPPPPPPPPPAHPAV---TVPPPPLPAPPGVPPPPILP 743
P PPP P P L P P AH + + PPPL AP P P P
Sbjct: 630 A-----PSPPPAPATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPEAPEPEP--P 682
Query: 744 PLPPFPPGLFPVMQVDMSHVLGGQWGGMPMSFQMQTQVLSRLMTGQG--ACPYPPFMAAA 801
P P P +H+ +P + T + ++ G A P A
Sbjct: 683 PADDSPAEPEPRAVGRTNHL------SLPRFAPVVTTPVKAEVSPHGAPALSNGPQTQAQ 736
Query: 802 AAAASAGLQFVNLPPYRGPFSLSNSGPGRGQHWPPLPKFDPSVPPPGYMPRQEDPHKATV 861
LQ L P P PP P+ P P P MP E KA +
Sbjct: 737 LLQPLQALQ-TQLLPQALP--------------PPQPQLQPP-PSPQQMPPLE---KARI 777
Query: 862 DGVLLVVLKELKAIMKRDLNRKMVEVVAFRAFDEWWDKKERMAKASLTPVKSGEHKDE 919
GV + L ++ M L R V++ D++++ A+ P+ G +E
Sbjct: 778 AGVGSLPLSGVEEKMFSLLKRAKVQLFKI-------DQQQQQKVAASMPLSPGGQMEE 828
Score = 64.7 bits (156), Expect = 8e-10
Identities = 95/362 (26%), Positives = 108/362 (29%), Gaps = 142/362 (39%)
Query: 427 EFRRAPAPPPLPPAEPLAKEKPGTPPGPPPPDTNSMELGGRPTFGWSPEPCDSPGTPTLE 486
E + P PP PPA P PP PPP T SP P P P
Sbjct: 397 EEAKLPPPPLTPPA-------PSPPPPLPPPST-------------SPPPPLCPPPPPPV 436
Query: 487 SSPAGPEKPHDSLDSRIEMLLKEQRTKLLFLREPDSDTELQMEGSPISSSSSQLSPLAPF 546
S P P P P E Q E P P+ P
Sbjct: 437 SPPPLPSPP------------------------PPPAQEEQEESPP---------PVVP- 462
Query: 547 GTNSQPGFRGPTPPSSRP----SSTGLEDISP-TPLPDSDEDEELDLGLGPRPPPEPGP- 600
T S+ R P PS R + G E SP TP P + PPE P
Sbjct: 463 ATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPTPST----------ATGGPPEDSPT 512
Query: 601 --PDPAGLLSQTAEVALDLVGDRTPTSEK-----MDEGQQSSGEDMEISDDEMPSAPITS 653
P L + + +V R+ K MDE
Sbjct: 513 VAPKSTTFLKNIRQFIMPVVSARSSRVIKTPRRFMDE----------------------- 549
Query: 654 ADCPKPMVVTPGAAAVAAPSVLAPTLPLPPPPGFPPLPPPPPPPPPQPGFPMPPPLPPPP 713
D PKP P V + PP PP+P P P P P P PP P P
Sbjct: 550 -DPPKP------------PKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPL 596
Query: 714 P---------------------PPPPAHPAVTVPPPPLPAPPGVPPP----PILPPLPPF 748
P PPPP P PPPP P+PP P P+L P F
Sbjct: 597 PEKRRSILREPTFRWTSLTRELPPPPPAP----PPPPAPSPPPAPATSSRRPLLLRAPQF 652
Query: 749 PP 750
P
Sbjct: 653 TP 654
Score = 60.8 bits (146), Expect = 1e-08
Identities = 30/59 (50%), Positives = 32/59 (54%), Gaps = 4/59 (6%)
Query: 694 PPPPPPQPGFPMPPPLPPPPPPPPPAHPAVTVPPPPL--PAPPGVPPPPILPPLPPFPP 750
P + P PP PP P PPPP P T PPPPL P PP V PPP+ P PP PP
Sbjct: 392 PAAEKEEAKLPPPPLTPPAPSPPPPLPPPSTSPPPPLCPPPPPPVSPPPL--PSPPPPP 448
Score = 52.0 bits (123), Expect = 6e-06
Identities = 23/40 (57%), Positives = 24/40 (60%), Gaps = 2/40 (5%)
Query: 715 PPPPAHPAVTVPPPPLPAPPGVPPPPILPPLPP--FPPGL 752
PPPP P PPPPLP P PPPP+ PP PP PP L
Sbjct: 402 PPPPLTPPAPSPPPPLPPPSTSPPPPLCPPPPPPVSPPPL 441
Score = 49.3 bits (116), Expect = 4e-05
Identities = 111/476 (23%), Positives = 149/476 (31%), Gaps = 95/476 (19%)
Query: 1177 PGAPAVDSLGME--EEVDIETEAVAPEERPSMLDEPPLPVGV--------EEPADSREPP 1226
P P + +E EE + AP P ++PPL V P + +PP
Sbjct: 1785 PWGPREEPAHLEAAEENQTIVHSPAPSSEPPGGEDPPLDTDVLVPGAPERHSPIQNLDPP 1844
Query: 1227 EEPGLSQEGAMLLSPEPPAKEVEAR---PPLSPERAPEHDLEVEPEPPMMLPLPLQPPLP 1283
P P P AR P SP R P + P P P L +P
Sbjct: 1845 LRPDSGSA-----PPPAPRSFSGARIKVPNYSPSRRPLGGVSFGPLPSPGSPSSLTHHIP 1899
Query: 1284 ---------PPRPPRPPSP-PPEPETTDASHPSVPPEPLAEDHPPHTPGLCGSLAKSQST 1333
PPR R PSP P P + + P + P PP + + S
Sbjct: 1900 TVGDPDFPAPPRRSRRPSPLAPRPPPSRWASPPLKTSPQLRVPPPTS---VVTALTPTSG 1956
Query: 1334 ETVPATPGGEPP--------------LSG-GSSGLSLSSPQVPGSPF------------S 1366
E P P PP +SG ++ L ++ + PF S
Sbjct: 1957 ELAPPGPAPSPPPPEDLGPDFEDMEVVSGLSAADLDFAASLLGTEPFQEEIVAAGAMGSS 2016
Query: 1367 YPAPSPSLSSGGLPRTPGRDFSFTPTFSEPSGPLLLPVCPL--PTGRRDERSGPLASPVL 1424
+ P S P + F T + P P P D+ + A V
Sbjct: 2017 HGGPGDSSEEESSPTSRYIHFPVTVVSAPGLAPSATPGAPRIEQLDGVDDGTDSEAEAVQ 2076
Query: 1425 LETGLPLPLPLPLPLPLALPAVLRAQARAPTPLP-PLLPAPLASCPPPMKRKPG-RPRRS 1482
G P P + + +AR P LP ++ L + P G R
Sbjct: 2077 QPRGQGTPPSGPGVVRAGVLGAAGDRARPPEDLPSEIVDFVLKNLGGPGDGGAGPREESL 2136
Query: 1483 PPSMLSLDGP-----LVRPPAGAALGRELLLLPGQPQTPVF---PSTHDPRTVT------ 1528
PP+ +G L PA R LPG P V P+ P+ T
Sbjct: 2137 PPAPPLANGSQPSQGLTASPADPT--RTFAWLPGAPGVRVLSLGPAPEPPKPATSKIILV 2194
Query: 1529 -----LDFRNAGIPAPPPPLPPQPPPPPPPPPVEPTKLPFKELDNQWPSEAIPPGP 1579
+ + AG P PP QPP PP P PT S +PPGP
Sbjct: 2195 NKLGQVFVKMAGEGEPVPPPVKQPPLPPTISPTAPT------------SWTLPPGP 2238
Score = 48.9 bits (115), Expect = 5e-05
Identities = 122/490 (24%), Positives = 155/490 (31%), Gaps = 102/490 (20%)
Query: 1144 EEEEEEEEMVAEESMASAGPEDFEQDGEEAALAPGAPAVDSLGMEEEVDIETEAVAPEER 1203
E EE + +V + +S P + + L PGAP S + + P R
Sbjct: 1796 EAAEENQTIVHSPAPSSEPPGGEDPPLDTDVLVPGAPERHS---------PIQNLDPPLR 1846
Query: 1204 PSMLDEPPLPVGVEEPADSREPPEEPGLSQEGAMLLSPEPPAKEVEARPPLSPERAPEHD 1263
P PP A + P P G + P P P SP H
Sbjct: 1847 PDSGSAPPPAPRSFSGARIKVPNYSPSRRPLGGVSFGPLPS--------PGSPSSLTHHI 1898
Query: 1264 LEVE----PEPPMML--PLPLQPPLPPPR---PPRPPSP----PPEPETTDASHPS---- 1306
V P PP P PL P PP R PP SP PP A P+
Sbjct: 1899 PTVGDPDFPAPPRRSRRPSPLAPRPPPSRWASPPLKTSPQLRVPPPTSVVTALTPTSGEL 1958
Query: 1307 VPPEPLAEDHPPHTPG------------------LCGSLAKSQ--STETVPATPGGEPPL 1346
PP P PP G SL ++ E V A G
Sbjct: 1959 APPGPAPSPPPPEDLGPDFEDMEVVSGLSAADLDFAASLLGTEPFQEEIVAAGAMGSSHG 2018
Query: 1347 SGGSSGLSLSSP-----QVPGSPFSYPAPSPSLSSGGLPRTPGRDFSFTPTFSEPSGPLL 1401
G S SSP P + S P +PS + G PR D T SE
Sbjct: 2019 GPGDSSEEESSPTSRYIHFPVTVVSAPGLAPSATPGA-PRIEQLDGVDDGTDSEAEA--- 2074
Query: 1402 LPVCPLPTGRRDERSGP--LASPVLLETGLPLPLPLPLPLPLALPAVLR--------AQA 1451
P G+ SGP + + VL G P LP + + VL+
Sbjct: 2075 ---VQQPRGQGTPPSGPGVVRAGVLGAAGDRARPPEDLPSEI-VDFVLKNLGGPGDGGAG 2130
Query: 1452 RAPTPLPPLLPAPLASCPPP-MKRKPGRPRRS------PPSMLSLD-GPLVRPPAGAA-- 1501
LPP P S P + P P R+ P + L GP PP A
Sbjct: 2131 PREESLPPAPPLANGSQPSQGLTASPADPTRTFAWLPGAPGVRVLSLGPAPEPPKPATSK 2190
Query: 1502 ------LGRELLLLPGQPQTPVFPSTHDPRTVTLD-FRNAGIPAPPPPL--------PPQ 1546
LG+ + + G+ + P P T+ PP PL +
Sbjct: 2191 IILVNKLGQVFVKMAGEGEPVPPPVKQPPLPPTISPTAPTSWTLPPGPLLGVLPVVGVVR 2250
Query: 1547 PPPPPPPPPV 1556
P PPPPPPP+
Sbjct: 2251 PAPPPPPPPL 2260
Score = 46.6 bits (109), Expect = 2e-04
Identities = 52/210 (24%), Positives = 75/210 (35%), Gaps = 29/210 (13%)
Query: 545 PFGTNSQPGFRGPTPPSSRPSSTGLEDISPTPLPDSDEDEELDLGLGPRPPPEPGPPDPA 604
P+G +P ++ + T + +P+ P ED LD + PG P+
Sbjct: 1785 PWGPREEPAHL----EAAEENQTIVHSPAPSSEPPGGEDPPLDTDV-----LVPGAPERH 1835
Query: 605 GLLSQTAEVALDLVGDRTPTSEKMDEGQQSSGEDMEISDDEMPSAPITSADCPKPMVVTP 664
+ G P + + G + + S P ++ P P +P
Sbjct: 1836 SPIQNLDPPLRPDSGSAPPPAPRSFSGARIKVPNY--SPSRRPLGGVSFGPLPSPG--SP 1891
Query: 665 GAAAVAAPSVLAPTLPLPPPPGFPPLPPPPPPPPPQPGFPMPPPLPPPP----PPPPPAH 720
+ P+V P P PP P P P PPP + PPL P PPP
Sbjct: 1892 SSLTHHIPTVGDPDFPAPPRRSRRPSPLAPRPPPSRWA---SPPLKTSPQLRVPPPTSVV 1948
Query: 721 PAVT------VPPPPLPAPPGVPPPPILPP 744
A+T PP P P+P PPP L P
Sbjct: 1949 TALTPTSGELAPPGPAPSP---PPPEDLGP 1975
Score = 44.7 bits (104), Expect = 9e-04
Identities = 86/366 (23%), Positives = 117/366 (31%), Gaps = 81/366 (22%)
Query: 374 DSATFAHTPPPAQATPAPGFKSAFSPYQTPVAHFPPPPEE-PTATAAF------GARDSG 426
DS A P Q TP G + PPE+ P+ F G D G
Sbjct: 2069 DSEAEAVQQPRGQGTPPSGPGVVRAGVLGAAGDRARPPEDLPSEIVDFVLKNLGGPGDGG 2128
Query: 427 EFRRAPAPPPLPPAEPLAKEKPGTPPGPPPPDTNSMELGGRPTFGWSPEPCDSPGTPTLE 486
R + PP PP ++ G P P TF W P +PG L
Sbjct: 2129 AGPREESLPPAPPLANGSQPSQGLTASPADPTR---------TFAWLP---GAPGVRVLS 2176
Query: 487 SSPAGPEKPHDSLDSRIEMLLKEQRTKLLFLREPDSDTELQMEGSPISSSSSQLSPLAPF 546
PA PE P K +K++ + + G + + P+ P
Sbjct: 2177 LGPA-PEPP------------KPATSKIILVNKL---------GQVFVKMAGEGEPVPP- 2213
Query: 547 GTNSQPGFRGPTPPSSRPSSTGLEDISPTPLPDSDEDEELDLGLGP-----RPPPEPGPP 601
P + P PP+ P++ + P PL LG+ P RP P P PP
Sbjct: 2214 -----PVKQPPLPPTISPTAPTSWTLPPGPL----------LGVLPVVGVVRPAPPPPPP 2258
Query: 602 D--------PAGLLSQTAEVA-LDLVGDRTPTSEKMDEGQQSSGEDMEISDDEMPSAPIT 652
PA Q V + R+P + + + ED E S+D +
Sbjct: 2259 PLTLVLSSGPASPPRQAIRVKRVSTFSGRSPPAPPPYKAPRLD-EDGEASEDTPQVPGLG 2317
Query: 653 SADCPKPMVVTPGAAAVAAPSVLAPTLPLPPPPGFPPLPPPPPPPPPQPGFPMPPPLPPP 712
S + + TP V L L P P P P P+P PP
Sbjct: 2318 SGGFSRVRMKTPTVRGV---------LDLDRPGEPAGEESPGPLQERSPLLPLPEDGPPQ 2368
Query: 713 PPPPPP 718
P PP
Sbjct: 2369 VPDGPP 2374
Score = 42.4 bits (98), Expect = 0.004
Identities = 87/389 (22%), Positives = 124/389 (31%), Gaps = 76/389 (19%)
Query: 355 GAVGGTGGSSGPPFKAQPQDSATFAHTPPPAQATPAPGFKSAFSPYQTPVAHFP------ 408
GA+G + G GP ++ + S T + P APG + +P +
Sbjct: 2011 GAMGSSHG--GPGDSSEEESSPTSRYIHFPVTVVSAPGLAPSATPGAPRIEQLDGVDDGT 2068
Query: 409 --------------PPPEEPTATAAFGARDSGEFRRAPAPPPLPPAEPLAKEKPGTPPG- 453
PP P A +G+ R P P + + K G G
Sbjct: 2069 DSEAEAVQQPRGQGTPPSGPGVVRAGVLGAAGDRARPPEDLPSEIVDFVLKNLGGPGDGG 2128
Query: 454 ---------PPPPDTNSMELGGRPTFGWSPEPCDS-------PGTPTLESSPAGP-EKPH 496
P PP N G +P+ G + P D PG P + GP +P
Sbjct: 2129 AGPREESLPPAPPLAN----GSQPSQGLTASPADPTRTFAWLPGAPGVRVLSLGPAPEPP 2184
Query: 497 DSLDSRIEMLLKEQRTKLLFLRE------PDSDTELQMEGSPISSSSSQLSPLAPFGTNS 550
S+I ++ K + + E P L SP + +S L P G
Sbjct: 2185 KPATSKIILVNKLGQVFVKMAGEGEPVPPPVKQPPLPPTISPTAPTSWTLPPGPLLGVLP 2244
Query: 551 QPGFRGPTPPSSRPSSTGLEDISPTPLPDSDEDEELDLGLGPRPPPEPGPPDPAGLLSQT 610
G P PP P T + P P + R PP P PP A L +
Sbjct: 2245 VVGVVRPAPPPPPPPLTLVLSSGPASPPRQAIRVKRVSTFSGRSPPAP-PPYKAPRLDED 2303
Query: 611 AEVALDLVGDRTPTSEKMDEG-----QQSSGEDMEISDDEMPSAPITSADCPKPMVVTPG 665
E + D TP + G + + + D + P P + P P+
Sbjct: 2304 GEASED-----TPQVPGLGSGGFSRVRMKTPTVRGVLDLDRPGEP-AGEESPGPL----- 2352
Query: 666 AAAVAAPSVLAPTLPLPP--PPGFPPLPP 692
+P LPLP PP P PP
Sbjct: 2353 -------QERSPLLPLPEDGPPQVPDGPP 2374
Score = 39.7 bits (91), Expect = 0.029
Identities = 57/204 (27%), Positives = 68/204 (33%), Gaps = 49/204 (24%)
Query: 602 DPAGLLSQTAEVALDLVGDRTPTSEKMDEGQQSSGEDMEISDDEM-PSAPIT-------- 652
+PA L + AE +V P+SE GED + D + P AP
Sbjct: 1791 EPAHL--EAAEENQTIVHSPAPSSEP------PGGEDPPLDTDVLVPGAPERHSPIQNLD 1842
Query: 653 ------SADCPKPMVVTPGAAAVAAPSVLAPTLPLP-------PPPGFPPLPPPPPPPPP 699
S P P + A + P+ PL P PG P P
Sbjct: 1843 PPLRPDSGSAPPPAPRSFSGARIKVPNYSPSRRPLGGVSFGPLPSPGSPSSLTHHIPTVG 1902
Query: 700 QPGFPMPPPL---PPPPPPPPP----------AHPAVTVPPP-----PLPAPPGVPPPPI 741
P FP PP P P P PP P + VPPP L G PP
Sbjct: 1903 DPDFPAPPRRSRRPSPLAPRPPPSRWASPPLKTSPQLRVPPPTSVVTALTPTSGELAPPG 1962
Query: 742 LPPLPPFPPGLFPVMQVDMSHVLG 765
P PP P L P + DM V G
Sbjct: 1963 PAPSPPPPEDLGPDFE-DMEVVSG 1985
Score = 38.1 bits (87), Expect = 0.084
Identities = 16/30 (53%), Positives = 18/30 (60%)
Query: 725 VPPPPLPAPPGVPPPPILPPLPPFPPGLFP 754
+PPPPL P PPPP+ PP PP L P
Sbjct: 401 LPPPPLTPPAPSPPPPLPPPSTSPPPPLCP 430
Score = 34.3 bits (77), Expect = 1.2
Identities = 43/153 (28%), Positives = 55/153 (35%), Gaps = 23/153 (15%)
Query: 1440 PLALPAVLRAQ-ARAP---------TPLPPLLPAPLASCPPPMKRKPGRPR--RSPPSML 1487
P +L + LR+Q RAP TPLPP A +A PP + P R R M+
Sbjct: 134 PSSLRSALRSQRGRAPRGRGRKHKTTPLPPPRLADVAPTPP---KTPARKRGEEGTERMV 190
Query: 1488 SLDGPLVRPPAGAALGRELLLLPGQPQTPVFPSTHDPRTVTLDFRNAGIPAPPPPLPPQP 1547
L+R R P P+ P + A + A P+P
Sbjct: 191 QALTELLRRAQAPQAPRSRACEPSTPRRSRGRPPGRPAGPCRRKQQAVVVAEAAVTIPKP 250
Query: 1548 PPPPPPPPVEPTKLPFKELDNQWPSEAIP-PGP 1579
PPPP PV K W + P PGP
Sbjct: 251 EPPPPVVPV-------KHQTGSWKCKEGPGPGP 276
Score = 32.3 bits (72), Expect = 4.6
Identities = 39/159 (24%), Positives = 54/159 (33%), Gaps = 23/159 (14%)
Query: 1176 APGAPAVDSLGMEEEVDIETEAVAPEER-----PSMLDEPPL-----PVGVEEPAD-SRE 1224
AP P + + + P E S+L PPL P PAD S
Sbjct: 630 APSPPPAPATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPEAPEPEPPPADDSPA 689
Query: 1225 PPEEPGLSQEGAMLLSPEPPAKEVEARPPLSPERAPEHDLEVEPEPPMMLPLP------- 1277
PE + + + L P + +SP AP + + ++ PL
Sbjct: 690 EPEPRAVGRTNHLSLPRFAPVVTTPVKAEVSPHGAPALSNGPQTQAQLLQPLQALQTQLL 749
Query: 1278 ---LQPPLPPPRPPRPPSPPPEPETTDASHPSVPPEPLA 1313
L PP P +P PPSP P A V PL+
Sbjct: 750 PQALPPPQPQLQP--PPSPQQMPPLEKARIAGVGSLPLS 786
>gi|56550039 myeloid/lymphoid or mixed-lineage leukemia protein [Homo
sapiens]
Length = 3969
Score = 155 bits (393), Expect = 3e-37
Identities = 80/153 (52%), Positives = 102/153 (66%), Gaps = 4/153 (2%)
Query: 1774 LKFNQLKFRKKK-LKFCKSHIHDWGLFAMEPIAADEMVIEYVGQNIRQVIADMREKRYED 1832
++F LK K+ + +S IH GLF I A EMVIEY G IR + D REK Y+
Sbjct: 3818 MRFRHLKKTSKEAVGVYRSPIHGRGLFCKRNIDAGEMVIEYAGNVIRSIQTDKREKYYDS 3877
Query: 1833 EGIGSSYMFRVDHDTIIDATKCGNFARFINHSCNPNCYAKVITVESQKKIVIYSKQHINV 1892
+GIG YMFR+D ++DAT GN ARFINHSC PNCY++VI ++ QK IVI++ + I
Sbjct: 3878 KGIGC-YMFRIDDSEVVDATMHGNAARFINHSCEPNCYSRVINIDGQKHIVIFAMRKIYR 3936
Query: 1893 NEEITYDYKFPIEDV--KIPCLCGSENCRGTLN 1923
EE+TYDYKFPIED K+PC CG++ CR LN
Sbjct: 3937 GEELTYDYKFPIEDASNKLPCNCGAKKCRKFLN 3969
Score = 44.3 bits (103), Expect = 0.001
Identities = 75/352 (21%), Positives = 107/352 (30%), Gaps = 64/352 (18%)
Query: 386 QATPAPGFKSAFSPYQTPVAHFPPPPEEPTATAAFGARD----SGEFRRAPAPPPLPPAE 441
+A A G K A P P P E ++ G D +G P PP+ P +
Sbjct: 1074 RAAVALGRKRAVFPDDMPTLSALPWEEREKILSSMGNDDKSSIAGSEDAEPLAPPIKPIK 1133
Query: 442 PLAKEKPGTPPGPPPPDTNSMELGGRPTFGWSPEPCDSPGTPTLESSPAGPEKPHDSLDS 501
P+ + K P PP G+ PE C T L+ G
Sbjct: 1134 PVTRNK--APQEPPVKKGRRSRRCGQCPGCQVPEDC-GVCTNCLDKPKFGGRN------- 1183
Query: 502 RIEMLLKEQRTKLLF---LREPDSDTELQMEGSPISSSSSQLSPLAPFGTNSQPGFRGPT 558
+K+Q K+ L+ S LQ + + + + +
Sbjct: 1184 -----IKKQCCKMRKCQNLQWMPSKAYLQKQAKAVKKKEKKSKTSEKKDSKESSVVKNVV 1238
Query: 559 PPSSRPSSTGLEDISPTPLPDSDEDEELDLGLGPRPPPEPGPPDPAGLLSQTAEVALDLV 618
S +P+ + ED P P S E PPP
Sbjct: 1239 DSSQKPTPSARED--PAPKKSSSE-----------PPP---------------------- 1263
Query: 619 GDRTPTSEKMDEGQQSSGEDMEISDDEMPSAPITSADCPKPMVVTPGAAAVAAPSVLAPT 678
R P EK +EG S+ E P++ +S +P +V P P P
Sbjct: 1264 --RKPVEEKSEEGNVSA-PGPESKQATTPASRKSSKQVSQPALVIPPQPPTTGP----PR 1316
Query: 679 LPLPPPPGFPPLPPPPPPPPPQPGFPMPPPLPPPPPPPPPAHPAVTVPPPPL 730
+P P PPPP P + P P P P PPP+
Sbjct: 1317 KEVPKTTPSEPKKKQPPPPESGPEQSKQKKVAPRPSIPVKQKPKEKEKPPPV 1368
Score = 40.0 bits (92), Expect = 0.022
Identities = 113/536 (21%), Positives = 186/536 (34%), Gaps = 99/536 (18%)
Query: 1033 GEEDEKESLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDESENDDEDTALSEASEKDEG 1092
G +D ES + +T + + + +E+ ++ DR E + E S K+E
Sbjct: 2719 GVDDGTESDTSVTATTRKSSQIPKRNGKENGTENLKIDRPEDAGEKEHVTKSSVGHKNEP 2778
Query: 1093 DSDEEETVSIVTSKAEATSSSESSESSEFESSSESSPSSSEDEEEVVAREEEEEEEEEEM 1152
D +VS V ++ + S ++ S ESS S+ D+ + E + + +
Sbjct: 2779 KMDNCHSVSRVKTQGQ---DSLEAQLSSLESSRRVHTSTPSDKNLLDTYNTELLKSDSDN 2835
Query: 1153 VAEESMASAGPEDFEQDGEEAALAPGAPAVDSLGMEEEVDIETEAVAPEERPSMLDEPPL 1212
+ + P D + P++ +LG E +E + E +
Sbjct: 2836 NNSDDCGNILPSDIMD-----FVLKNTPSMQALG-ESPESSSSELLNLGEGLGLDSNREK 2889
Query: 1213 PVGVEEPADSREPPEEP-------GLSQEGAMLLSPEPPA--KEVEARPPLSPERAPEHD 1263
+G+ E + P EP +S E L E P+ + R P P + P
Sbjct: 2890 DMGLFEVFSQQLPTTEPVDSSVSSSISAEEQFELPLELPSDLSVLTTRSPTVPSQNPSRL 2949
Query: 1264 LEVEPEPPMMLPLPLQPPLPPPRPPRPPSP--PPEPE-----------TTDASHPSVPPE 1310
+ + + + P SP P PE DA H S PP
Sbjct: 2950 AVISDSGEKRVTITEKSVASSESDPALLSPGVDPTPEGHMTPDHFIQGHMDADHISSPP- 3008
Query: 1311 PLAEDHPPHTPGLCGSL----AKSQSTETVPATPGGEPPLSGGSSGLSLSSPQVPGS--- 1363
CGS+ +Q +TPG + P+ SP VP
Sbjct: 3009 -------------CGSVEQGHGNNQDLTRNSSTPGLQVPV----------SPTVPIQNQK 3045
Query: 1364 --PFSYPAPSPSLSSGGLPRTPGRDFSFTPTFSEPSGPLLLPV----------CPLPTGR 1411
P S +P PS S +T TP +P+ L+ V LP G
Sbjct: 3046 YVPNSTDSPGPSQISNAAVQT-------TPPHLKPATEKLIVVNQNMQPLYVLQTLPNGV 3098
Query: 1412 RDE---RSGPLASPVLLETGLPLPLPLPLPLPLAL---PAVLRAQARAPTPLPPLLPAPL 1465
+ S ++P ++ET + P+ L L P++ +Q+ P+ LLP
Sbjct: 3099 TQKIQLTSSVSSTPSVMETNTSVLGPMGGGLTLTTGLNPSLPTSQSLFPSASKGLLP--- 3155
Query: 1466 ASCPPPMKRKPGRPRRSPPSMLSLDGPLVRPPAGAALGRELLLLPGQPQTPVFPST 1521
S + P + S P +S PP+G +G + P PQ V S+
Sbjct: 3156 MSHHQHLHSFPAATQSSFPPNIS------NPPSGLLIG---VQPPPDPQLLVSESS 3202
Score = 39.7 bits (91), Expect = 0.029
Identities = 37/126 (29%), Positives = 57/126 (45%), Gaps = 17/126 (13%)
Query: 1209 EPPLPVGVEEPA----DSREPPEEP--GLSQEGAMLLSPEPPAKEVEARPPL-SPERAPE 1261
+ P P E+PA S PP +P S+EG + +P P +K+ S ++ +
Sbjct: 1242 QKPTPSAREDPAPKKSSSEPPPRKPVEEKSEEGNVS-APGPESKQATTPASRKSSKQVSQ 1300
Query: 1262 HDLEVEPEPPMMLPLPLQ-PPLPPPRPPRPPSPPPE--PETTD----ASHPSVP--PEPL 1312
L + P+PP P + P P P + PPPE PE + A PS+P +P
Sbjct: 1301 PALVIPPQPPTTGPPRKEVPKTTPSEPKKKQPPPPESGPEQSKQKKVAPRPSIPVKQKPK 1360
Query: 1313 AEDHPP 1318
++ PP
Sbjct: 1361 EKEKPP 1366
Score = 39.3 bits (90), Expect = 0.037
Identities = 42/148 (28%), Positives = 54/148 (36%), Gaps = 30/148 (20%)
Query: 1451 ARAPTPLPPLLPAPLASCPPPMKRKPGRPRRSPPSMLSLDGP---LVRPPAGAALGREL- 1506
++ PTP PAP S P RKP +S +S GP PA +++
Sbjct: 1241 SQKPTPSAREDPAPKKSSSEPPPRKPVE-EKSEEGNVSAPGPESKQATTPASRKSSKQVS 1299
Query: 1507 ---LLLPGQPQTPVFPSTHDPRTVTLDFRNAGIPAPPPPLPPQPPPPPPPPPVEPTK--- 1560
L++P QP T P P+T P P QPPPP P K
Sbjct: 1300 QPALVIPPQPPTTGPPRKEVPKT-----------TPSEPKKKQPPPPESGPEQSKQKKVA 1348
Query: 1561 ----LPFKELDNQWPSEAIPPGPRGRDE 1584
+P K Q P E P P + E
Sbjct: 1349 PRPSIPVK----QKPKEKEKPPPVNKQE 1372
Score = 37.4 bits (85), Expect = 0.14
Identities = 45/209 (21%), Positives = 71/209 (33%), Gaps = 59/209 (28%)
Query: 1097 EETVSIVTSKAEATSSSESSESSE-------FESSSESSPSSSEDEEEVVAREEEEEEEE 1149
++ V K + + +SE +S E +SS + +PS+ ED + E +
Sbjct: 1207 QKQAKAVKKKEKKSKTSEKKDSKESSVVKNVVDSSQKPTPSAREDPAPKKSSSEPPPRKP 1266
Query: 1150 EEMVAEESMASA-GPEDFEQDGEEAALAPGAPAVDSLGMEEEVDIETEAVAPEERPS--M 1206
E +EE SA GPE +A P R S
Sbjct: 1267 VEEKSEEGNVSAPGPES-----------------------------KQATTPASRKSSKQ 1297
Query: 1207 LDEPPLPVGVEEPADSREPPEEPGLSQEGAMLLSPEPPAKEVEARPPLSPERAPEHDLEV 1266
+ +P L + PP+ P + PP KEV P P++ E
Sbjct: 1298 VSQPALVI----------PPQPP----------TTGPPRKEVPKTTPSEPKKKQPPPPES 1337
Query: 1267 EPEPPMMLPLPLQPPLPPPRPPRPPSPPP 1295
PE + +P +P + P+ PP
Sbjct: 1338 GPEQSKQKKVAPRPSIPVKQKPKEKEKPP 1366
Score = 36.2 bits (82), Expect = 0.32
Identities = 37/129 (28%), Positives = 48/129 (37%), Gaps = 25/129 (19%)
Query: 383 PPAQATPAPGFKSAFSPYQTPVAH-------FPPPPEEPTATAAFGARDSGEFRRAPA-- 433
P A+ PAP S+ P + PV P PE AT + S + + PA
Sbjct: 1246 PSAREDPAPKKSSSEPPPRKPVEEKSEEGNVSAPGPESKQATTPASRKSSKQVSQ-PALV 1304
Query: 434 -PPPLPPAEPLAKEKPGTPPG------PPPPDTNSMELGGRPTFGWSPEPCDSPGTPTLE 486
PP P P KE P T P PPPP++ P + P P ++
Sbjct: 1305 IPPQPPTTGPPRKEVPKTTPSEPKKKQPPPPESG-------PEQSKQKKVAPRPSIP-VK 1356
Query: 487 SSPAGPEKP 495
P EKP
Sbjct: 1357 QKPKEKEKP 1365
Score = 35.4 bits (80), Expect = 0.54
Identities = 24/67 (35%), Positives = 31/67 (46%), Gaps = 6/67 (8%)
Query: 1318 PHTPGLCGSLAKSQSTETVPATPGGEPPLSGGSSGLSLSSPQVPGSPFSYPAPSPSLSSG 1377
P++ GL + A S + + P +PGG P S SSG +SP VPG P P
Sbjct: 3490 PNSMGLEQNKALSSAVQASPTSPGGSP--SSPSSGQRSASPSVPGP----TKPKPKTKRF 3543
Query: 1378 GLPRTPG 1384
LP G
Sbjct: 3544 QLPLDKG 3550
Score = 33.9 bits (76), Expect = 1.6
Identities = 43/196 (21%), Positives = 69/196 (35%), Gaps = 42/196 (21%)
Query: 1114 ESSESSEFESSSESSPSSSEDEEEVVAREEEEEEEEEEMVAEESMASAGPEDFEQDGEEA 1173
ES+ +S F S+PS E+ A + +M ++ S +S+ D D + +
Sbjct: 444 ESTPNSRF-----SAPSCGSSEKSSAA-----SQHSSQMSSDSSRSSSPSVDTSTDSQAS 493
Query: 1174 ALAPGAPAVDSLGMEEEVDIETEAVAPEERPSMLD-EPPLPVGVEEPADSREPPEEPGLS 1232
EE+ V PEER + PPLP+ + PE
Sbjct: 494 ---------------EEIQ-----VLPEERSDTPEVHPPLPIS--------QSPENESND 525
Query: 1233 QEGAMLLSPEPPAKEVEARPPLSPERAPEHDLEVEPEPPMMLPLPLQPPLPPPRPPRPPS 1292
+ E + + + AP+ P PP++ P PPL P +
Sbjct: 526 RRSRRYSVSERSFGSRTTKKLSTLQSAPQQQTSSSPPPPLLTP---PPPLQPASSISDHT 582
Query: 1293 PPPEPETTDASHPSVP 1308
P P T + P +P
Sbjct: 583 PWLMPPTIPLASPFLP 598
Score = 32.0 bits (71), Expect = 6.0
Identities = 23/68 (33%), Positives = 28/68 (41%), Gaps = 8/68 (11%)
Query: 697 PPPQPGFPMPPPLPPPPPPPPPAHPAVTVPPPPLPAPPGVPPPPILPPLPPFPPGLFPVM 756
P Q PPPL PPPP PA +++ P L PP +P PF P M
Sbjct: 553 PQQQTSSSPPPPLLTPPPPLQPA-SSISDHTPWL-------MPPTIPLASPFLPASTAPM 604
Query: 757 QVDMSHVL 764
Q +L
Sbjct: 605 QGKRKSIL 612
>gi|91718902 myeloid/lymphoid or mixed-lineage leukemia 3 [Homo
sapiens]
Length = 4911
Score = 137 bits (344), Expect = 1e-31
Identities = 80/211 (37%), Positives = 111/211 (52%), Gaps = 10/211 (4%)
Query: 1721 LNSSRASTDEPPADTQGMSIPAQPHASTRAGSERRSEQRRLLSSFTGSCDSDLLKFNQLK 1780
+N + + EP +PH + + S +S Q + + +
Sbjct: 4703 VNPTGCARSEPKMSAHVKRFVLRPH-TLNSTSTSKSFQSTVTGELNAPYSKQFVHSKSSQ 4761
Query: 1781 FRKKKLKF------CKSHIHDWGLFAMEPIAADEMVIEYVGQNIRQVIADMREKRYEDEG 1834
+RK K ++ +S I GL+A I MVIEY+G IR +A+ +EK YE +
Sbjct: 4762 YRKMKTEWKSNVYLARSRIQGLGLYAARDIEKHTMVIEYIGTIIRNEVANRKEKLYESQN 4821
Query: 1835 IGSSYMFRVDHDTIIDATKCGNFARFINHSCNPNCYAKVITVESQKKIVIYSKQHINVNE 1894
G YMFR+D+D +IDAT G AR+INHSC PNC A+V+T E KI+I S + I E
Sbjct: 4822 RGV-YMFRMDNDHVIDATLTGGPARYINHSCAPNCVAEVVTFERGHKIIISSSRRIQKGE 4880
Query: 1895 EITYDYKFPIED--VKIPCLCGSENCRGTLN 1923
E+ YDYKF ED KIPC CG+ NCR +N
Sbjct: 4881 ELCYDYKFDFEDDQHKIPCHCGAVNCRKWMN 4911
Score = 53.5 bits (127), Expect = 2e-06
Identities = 124/580 (21%), Positives = 184/580 (31%), Gaps = 99/580 (17%)
Query: 367 PFKAQPQDSATFAHTP-PPAQATPAPGFKSAFSPY-QTPVAHFPPPPEEPTATAAFGARD 424
P + QDS + A T PP+ +PG ++ P P A P P +F R+
Sbjct: 1859 PSRIPIQDSLSQAQTSQPPSPQVFSPGSSNSRPPSPMDPYAKMVGTPRPPPVGHSFSRRN 1918
Query: 425 SG----------------EFRRAPAPPPLPPAEPLAKEKPGTPPGPPPPDTNSMELGGR- 467
S + A P P + + P PPDT + +
Sbjct: 1919 SAAPVENCTPLSSVSRPLQMNETTANRPSPVRDLCSSSTTNNDPYAKPPDTPRPVMTDQF 1978
Query: 468 -PTFGWSPEPCDSPGTPTLESSPAGPEKPHDSLDSRIEMLLKEQRTKLLFLREPDSDTEL 526
+ G S P S T + A H + S + + QR PDS
Sbjct: 1979 PKSLGLSRSPVVSE--QTAKGPIAAGTSDHFTKPSPRADVFQRQRI-------PDSYARP 2029
Query: 527 QMEGSPISSSSSQL--------SPLAPFGTNSQPGFRGPTPPSSRPSSTGLEDISPTPLP 578
+ +P+ S S P+G+ SQ R P RP+ T P P+
Sbjct: 2030 LLTPAPLDSGPGPFKTPMQPPPSSQDPYGSVSQASRRLSVDPYERPALT------PRPID 2083
Query: 579 DSDEDEELDLGLGPRPPPEPGPPD----PAGLLSQTAEVALDLVGD---RTPTSEK--MD 629
+ ++ D P P P + P+ SQ ++ D + P + + +D
Sbjct: 2084 NFSHNQSNDPYSQPPLTPHPAVNESFAHPSRAFSQPGTISRPTSQDPYSQPPGTPRPVVD 2143
Query: 630 EGQQSSGEDMEISDDEMPSAPITSADCPKPMVVTPGAAA--VAAPSVLAPTLPLPPPPGF 687
QSSG + D P T P+P V P + PS P
Sbjct: 2144 SYSQSSGTARS-NTDPYSQPPGT----PRPTTVDPYSQQPQTPRPSTQTDLFVTPVTNQR 2198
Query: 688 PPLPPPPPPPPPQPGFPMPPPLPPPPPPP-----------------PPAHPAVTVPPPPL 730
P PP P+PG +P PP P P P P +
Sbjct: 2199 HSDPYAHPPGTPRPGISVPYSQPPATPRPRISEGFTRSSMTRPVLMPNQDPFLQAAQNRG 2258
Query: 731 PAPPG--VPPPPILPPLP-PFPPGLFPVMQVDMSHVLGGQWGGMPMSFQMQTQVLSRLMT 787
PA PG V PP P P PGL + PM+ + Q+ T
Sbjct: 2259 PALPGPLVRPPDTCSQTPRPPGPGLSDTFSRVSPSAARDPYDQSPMTPRSQSDSFGTSQT 2318
Query: 788 GQGACPYPPFMAAAAAAASAGLQFVNLPPYRGPFSLSNSGP--GRGQHWPPLPKFDPSVP 845
P P G F S++ P +GQ + + + VP
Sbjct: 2319 AHDVADQP------------------RPGSEGSFCASSNSPMHSQGQQFSGVSQLPGPVP 2360
Query: 846 PPGYMPRQEDPHKATVDGVLLVVLKELKAIMKRDLNRKMV 885
G Q + A D L ++L+ I+ + +K +
Sbjct: 2361 TSGVTDTQNTVNMAQADTEKLRQRQKLREIILQQQQQKKI 2400
Score = 53.1 bits (126), Expect = 3e-06
Identities = 107/452 (23%), Positives = 144/452 (31%), Gaps = 116/452 (25%)
Query: 388 TPAPGFKSAFSPY-----QTPVAHF------PPPPEEPTATAAFGARDSGEFRRAPAPPP 436
TP+ G +S +P +P F PP PT+T++ D +AP PPP
Sbjct: 1801 TPSSGIQSPLTPQPGNGNMSPAQSFHKELFTKQPPSTPTSTSS---DDVFVKPQAPPPPP 1857
Query: 437 LPPAEP----LAKEKPGTPPGP---PPPDTNSMELGGRPTFGWSPEPCDSPGTPTLESSP 489
P P L++ + PP P P +NS RP P P D + +P
Sbjct: 1858 APSRIPIQDSLSQAQTSQPPSPQVFSPGSSNS-----RP-----PSPMDP--YAKMVGTP 1905
Query: 490 AGPEKPHDSLDSRIEMLLKEQRTKLLFLREPDSDTELQMEGSPISSSSSQLSPLAPFGTN 549
P H S R E T L + P LQM + + S + TN
Sbjct: 1906 RPPPVGH-SFSRRNSAAPVENCTPLSSVSRP-----LQMNETTANRPSPVRDLCSSSTTN 1959
Query: 550 SQPGFRGPTPP------------------------SSRPSSTGLEDISPTPLPDSDEDEE 585
+ P + P P + P + G D P P +D +
Sbjct: 1960 NDPYAKPPDTPRPVMTDQFPKSLGLSRSPVVSEQTAKGPIAAGTSDHFTKPSPRADVFQR 2019
Query: 586 ----------------LDLGLGPRPPPEPGPP---DPAGLLSQTA-EVALDLVGDRTPTS 625
LD G GP P PP DP G +SQ + +++D T
Sbjct: 2020 QRIPDSYARPLLTPAPLDSGPGPFKTPMQPPPSSQDPYGSVSQASRRLSVDPYERPALTP 2079
Query: 626 EKMDEGQQSSGEDMEISDDEMPSAPITSADCPKPMVVTPGAAAVAAPSVLAPTL--PLPP 683
+D + S+D P+T P A ++ PT P
Sbjct: 2080 RPIDNFSHNQ------SNDPYSQPPLTPHPAVNESFAHPSRAFSQPGTISRPTSQDPYSQ 2133
Query: 684 PPGFP------------PLPPPPPPPPPQPGFPMPPPLPP----PPPPPPPAHPAVTVPP 727
PPG P P PG P P + P P P P + V P
Sbjct: 2134 PPGTPRPVVDSYSQSSGTARSNTDPYSQPPGTPRPTTVDPYSQQPQTPRPSTQTDLFVTP 2193
Query: 728 -------PPLPAPPGVPPPPILPPL--PPFPP 750
P PPG P P I P PP P
Sbjct: 2194 VTNQRHSDPYAHPPGTPRPGISVPYSQPPATP 2225
Score = 50.1 bits (118), Expect = 2e-05
Identities = 104/429 (24%), Positives = 155/429 (36%), Gaps = 83/429 (19%)
Query: 1215 GVEEPADSREPPEEPGLSQEGAMLLSPEPPA-KEVEAR-PPLSPERAPEHDLEVEPE--- 1269
G + P+ + P P Q G +SP KE+ + PP +P D+ V+P+
Sbjct: 1798 GSDTPSSGIQSPLTP---QPGNGNMSPAQSFHKELFTKQPPSTPTSTSSDDVFVKPQAPP 1854
Query: 1270 -PPMMLPLPLQPPLPPPRPPRPPSPPPEPETTDASHPSVPPEPLAE-DHPPHTPGLCGSL 1327
PP +P+Q L + +PPSP + S P P +P A+ P P + S
Sbjct: 1855 PPPAPSRIPIQDSLSQAQTSQPPSPQVFSPGSSNSRPPSPMDPYAKMVGTPRPPPVGHSF 1914
Query: 1328 AKSQSTETVPATPGGEPPLSGGSSGLSL---------------SSPQVPGSPFSYPAPSP 1372
++ S V PLS S L + SS P++ P +P
Sbjct: 1915 SRRNSAAPVENC----TPLSSVSRPLQMNETTANRPSPVRDLCSSSTTNNDPYAKPPDTP 1970
Query: 1373 -SLSSGGLPRTPGRDFSFTPTFSEPS--GPLLLPVC-----PLPTGR-------RDERSG 1417
+ + P++ G S +P SE + GP+ P P D +
Sbjct: 1971 RPVMTDQFPKSLG--LSRSPVVSEQTAKGPIAAGTSDHFTKPSPRADVFQRQRIPDSYAR 2028
Query: 1418 PLASPVLLETGLPLPLPLPLPLPLA----LPAVLRAQARA---PTPLPPLLPAPLAS--- 1467
PL +P L++G P P P+ P + +V +A R P P L P P+ +
Sbjct: 2029 PLLTPAPLDSG-PGPFKTPMQPPPSSQDPYGSVSQASRRLSVDPYERPALTPRPIDNFSH 2087
Query: 1468 -------CPPPMKRKP--GRPRRSPPSMLSLDGPLVRPPAGAALGRELLLLPGQPQTPVF 1518
PP+ P P S G + RP + + PG P+ V
Sbjct: 2088 NQSNDPYSQPPLTPHPAVNESFAHPSRAFSQPGTISRPTSQDPYSQP----PGTPRPVVD 2143
Query: 1519 PSTHDPRTVTLDFRNAGIPAPPPPLPPQP-------PPPPPPPPVEPTKLPFKELDNQWP 1571
+ T R+ P PP P+P P P P T L + NQ
Sbjct: 2144 SYSQSSGTA----RSNTDPYSQPPGTPRPTTVDPYSQQPQTPRPSTQTDLFVTPVTNQRH 2199
Query: 1572 SE--AIPPG 1578
S+ A PPG
Sbjct: 2200 SDPYAHPPG 2208
Score = 48.1 bits (113), Expect = 8e-05
Identities = 88/334 (26%), Positives = 116/334 (34%), Gaps = 74/334 (22%)
Query: 1203 RPSMLDEPPLPVGVEE-PADSREPPEEPGLSQEGAMLLSPEPPAKEVE--------ARPP 1253
RP M D+ P +G+ P S + + P + P P A + ARP
Sbjct: 1971 RPVMTDQFPKSLGLSRSPVVSEQTAKGPIAAGTSDHFTKPSPRADVFQRQRIPDSYARPL 2030
Query: 1254 LSPERAPEHDLEVEPEP---PMMLPLPLQPPL-------------PPPRP---PRPPSPP 1294
L+P AP L+ P P PM P Q P P RP PRP
Sbjct: 2031 LTP--AP---LDSGPGPFKTPMQPPPSSQDPYGSVSQASRRLSVDPYERPALTPRPIDNF 2085
Query: 1295 PEPETTDA-SHPSVPPEPLAED---HPPHTPGLCGSLAKSQSTETVPATPGGEPPLSGG- 1349
++ D S P + P P + HP G++++ S + PG P+
Sbjct: 2086 SHNQSNDPYSQPPLTPHPAVNESFAHPSRAFSQPGTISRPTSQDPYSQPPGTPRPVVDSY 2145
Query: 1350 --SSGLSLSSPQVPGSPFSYPAPSPSLSSGGLPRTPGRD-FSFTPTFSEPSGPLLLPVCP 1406
SSG + S+ P+S P G PR D +S P PS L V P
Sbjct: 2146 SQSSGTARSNTD----PYSQPP--------GTPRPTTVDPYSQQPQTPRPSTQTDLFVTP 2193
Query: 1407 LPTGRRDERSGPLASPVLLETGLPLP---LPLPLPLPLALPAVLRAQARAPTPLPPLLPA 1463
+ R S P A P G P P +P P P + R+ P L+P
Sbjct: 2194 VTNQRH---SDPYAHP----PGTPRPGISVPYSQPPATPRPRISEGFTRSSMTRPVLMPN 2246
Query: 1464 PLASCPPPMKRKPGRPRRSPPSMLSLDGPLVRPP 1497
R P P GPLVRPP
Sbjct: 2247 QDPFLQAAQNRGPALP-----------GPLVRPP 2269
Score = 42.4 bits (98), Expect = 0.004
Identities = 131/606 (21%), Positives = 190/606 (31%), Gaps = 123/606 (20%)
Query: 252 FSQDTAYSSCRLDTPNSYGQGTP------LTPRLGTPFSQDSSYS----SRQPTPSYLFS 301
FSQ S P S GTP + GT S YS + +PT +S
Sbjct: 2116 FSQPGTISRPTSQDPYSQPPGTPRPVVDSYSQSSGTARSNTDPYSQPPGTPRPTTVDPYS 2175
Query: 302 QDPAVTFKARRHESKFTDAYNRRHEHHYVH-------------NSPAVTAVAGATAAFRG 348
Q P + + + T N+RH Y H + P T + F
Sbjct: 2176 QQPQTPRPSTQTDLFVTPVTNQRHSDPYAHPPGTPRPGISVPYSQPPATPRPRISEGFTR 2235
Query: 349 SSDL---------PFGAVGGTGGSSGPPFKAQPQDSATFAHTPPPAQATPAPGFKSAFSP 399
SS PF G + P +P D T + TP P P PG FS
Sbjct: 2236 SSMTRPVLMPNQDPFLQAAQNRGPALPGPLVRPPD--TCSQTPRP----PGPGLSDTFSR 2289
Query: 400 YQTPVAHFPPPPEEPTATAAFGARDSGEFRRAPAPPPLPPAEPLAKEKPGTPPGPPPPDT 459
A P T + + + + A P P +E +P
Sbjct: 2290 VSPSAARDPYDQSPMTPRSQSDSFGTSQTAHDVADQPRPGSEGSFCASSNSP-------- 2341
Query: 460 NSMELGGRPTFGWS--PEPCDSPGTP----TLESSPAGPEKPHDSLDSRIEMLLKEQRTK 513
M G+ G S P P + G T+ + A EK R E++L++Q+ K
Sbjct: 2342 --MHSQGQQFSGVSQLPGPVPTSGVTDTQNTVNMAQADTEKLRQRQKLR-EIILQQQQQK 2398
Query: 514 LLFLREPDSDTELQMEGSPISSSSSQLSPLAPFGTNSQPGFRGPTPPSSRPSSTGLEDIS 573
+ R+ E + SP L P N F P PP P + S
Sbjct: 2399 KIAGRQ-----EKGSQDSPAVPHPGPLQHWQPENVNQ--AFTRPPPPY--PGNIR----S 2445
Query: 574 PTPLPDSDEDEELDLGLGPRPPPEPGPPDPAGLLSQTAEVALDLVGDR---TPTSEKM-- 628
P P + P+ P PPD A + + G P+ E+
Sbjct: 2446 PVAPPLGPR-----YAVFPKDQRGPYPPDVASMGMRPHGFRFGFPGGSHGTMPSQERFLV 2500
Query: 629 -DEGQQSSGEDMEISDDEMPSAPITSADCPKPMVVTPGAAAVAAPSVLAP-TLPLPP--- 683
+ Q SG ++ S D P+P+ + V P +P +LP+
Sbjct: 2501 PPQQIQGSGVSPQLRRS-------VSVDMPRPLNNSQMNNPVGLPQHFSPQSLPVQQHNI 2553
Query: 684 ------------PPGFPPLPPPPPPPP--------------PQPGFPMPPPLPPPPPPPP 717
P G LP PP P+P FP P P PP
Sbjct: 2554 LGQAYIELRHRAPDGRQRLPFSAPPGSVVEASSNLRHGNFIPRPDFPGPRHTDPMRRPPQ 2613
Query: 718 PAHPAVTVPPPPLPAPPGVPPPPILPPLPPFPPGLFPVMQVDMSHVLGGQWGGMPMSFQM 777
P LP P + P ++ ++H LGG++ P+S +
Sbjct: 2614 GL-------PNQLPVHPDLEQVPPSQQEQGHSVHSSSMVMRTLNHPLGGEFSEAPLSTSV 2666
Query: 778 QTQVLS 783
++ S
Sbjct: 2667 PSETTS 2672
Score = 41.6 bits (96), Expect = 0.008
Identities = 122/503 (24%), Positives = 170/503 (33%), Gaps = 112/503 (22%)
Query: 266 PNSYGQGTPLTPRLGTPFSQDSS----YSSRQPTPSYLFSQDP--AVTFKARRHESKFTD 319
P+SY + PL TP DS + QP PS SQDP +V+ +RR D
Sbjct: 2023 PDSYAR--PLL----TPAPLDSGPGPFKTPMQPPPS---SQDPYGSVSQASRRLS---VD 2070
Query: 320 AYNRRHEHHYVHNSPAVTAVAGATAAFRGSSDLPFGAVGGTGGSSGPPFKAQPQDSATFA 379
Y R PA+T + S+D P+ S PP P + +FA
Sbjct: 2071 PYER----------PALTPRPIDNFSHNQSND-PY---------SQPPLTPHPAVNESFA 2110
Query: 380 HTPPPAQATPAPGFKSAFSPYQTPVAHFPPPPEEPTATAAFGARDSGEFRRAPAPPPLPP 439
H P++A PG S T + PP P ++ SG R P PP
Sbjct: 2111 H---PSRAFSQPGTISR----PTSQDPYSQPPGTPRPVVDSYSQSSGTARSNTDPYSQPP 2163
Query: 440 A--EPLAKEKPGTPPGPPPPDTNSMELGGRPTFGWSPEP-CDSPGTP-----TLESSPAG 491
P + P P P T + T +P PGTP S P
Sbjct: 2164 GTPRPTTVDPYSQQPQTPRPSTQTDLFVTPVTNQRHSDPYAHPPGTPRPGISVPYSQPPA 2223
Query: 492 PEKPHDS----LDSRIEMLLKEQRTKLL-------------FLREPDSDTELQMEGSP-I 533
+P S S +L + L +R PD+ ++ P +
Sbjct: 2224 TPRPRISEGFTRSSMTRPVLMPNQDPFLQAAQNRGPALPGPLVRPPDTCSQTPRPPGPGL 2283
Query: 534 SSSSSQLSPLAPFGTNSQPGFRGPTPPSSRPSSTGLE----DISPTPLPDSDED------ 583
S + S++SP A P + P P S+ S G D++ P P S+
Sbjct: 2284 SDTFSRVSPSAA----RDPYDQSPMTPRSQSDSFGTSQTAHDVADQPRPGSEGSFCASSN 2339
Query: 584 --------EELDLGLGPRPPPEPGPPDPAGLLSQTAEVALDLVGDRTPTSEKMDEGQQS- 634
+ + P P P G D ++ A+ + + R E + + QQ
Sbjct: 2340 SPMHSQGQQFSGVSQLPGPVPTSGVTDTQNTVNM-AQADTEKLRQRQKLREIILQQQQQK 2398
Query: 635 --SGEDMEISDDEMPSAPITSADCPKPMVVTPGAAAVAAPSVL--APTLPLPPPPGFPPL 690
+G + S D P V PG P + A T P PP PG
Sbjct: 2399 KIAGRQEKGSQDS-------------PAVPHPGPLQHWQPENVNQAFTRPPPPYPGNIRS 2445
Query: 691 PPPPPPPPPQPGFPMPPPLPPPP 713
P PP P FP P PP
Sbjct: 2446 PVAPPLGPRYAVFPKDQRGPYPP 2468
Score = 38.9 bits (89), Expect = 0.049
Identities = 80/413 (19%), Positives = 149/413 (36%), Gaps = 39/413 (9%)
Query: 1025 RPLELDSGGEEDEKE-SLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDESENDDEDTAL 1083
R L GGE E S S E+T + + + + ++ DSDD E D +D
Sbjct: 2647 RTLNHPLGGEFSEAPLSTSVPSETTSDNLQITTQPSDGLEEKLDSDDPSVKELDVKDLEG 2706
Query: 1084 SEASEKDEG-------DSDEEETVSIVTSKAEATSSSESSE---SSEFESSSESSPSSSE 1133
E + D+ D+++ + V + T T+ + S EF+ + + P
Sbjct: 2707 VEVKDLDDEDLENLNLDTEDGKVVELDTLDNLETNDPNLDDLLRSGEFDIIAYTDPELDM 2766
Query: 1134 DEEEVVAREEEEEEEEEEMVAEESMASAGPEDFEQDGEEAALA-----------PGAPAV 1182
+++ + EE + ++++ + S P+ EQ+ + L+
Sbjct: 2767 GDKKSMFNEELDLPIDDKL--DNQCVSVEPKKKEQENKTLVLSDKHSPQKKSTVTNEVKT 2824
Query: 1183 DSLGMEEEVDIETEAVAPEERPSMLDEPPLPVGVEEPADSREP----PEEPGLSQEGAML 1238
+ L +V+ + E +E +D P + E P +P L ++
Sbjct: 2825 EVLSPNSKVESKCETEKNDENKDNVDTPCSQASAHSDLNDGEKTSLHPCDPDLFEKRTNR 2884
Query: 1239 LSPEPPAKEVEARPPLSPERAPEHDLEVEPEPPMMLPLPL-----QPPLPPPRPPRPPSP 1293
+ P A ++A L P + + + P++ L + P P PP+
Sbjct: 2885 ETAGPSANVIQASTQL-PAQDVINSCGITGSTPVLSSLLANEKSDNSDIRPSGSPPPPTL 2943
Query: 1294 PPEPETTDAS-HPSVPPEPLAEDHPPHTPGLCGSLAKSQSTETVPATPGGEPPLSGGSSG 1352
P P +S P + P D+ ++ S ++ V PG P S +
Sbjct: 2944 PASPSNHVSSLPPFIAPPGRVLDNAMNSNVTVVSRVNHVFSQGVQVNPGLIPGQSTVNHS 3003
Query: 1353 LSLSSPQVPGSPFSYPAPSPSLSSGG---LPRTPGRDFSFTPTFSEPSGPLLL 1402
L P P + + + S+S +P+T + P E PLLL
Sbjct: 3004 LGTGKPATQTGPQTSQSGTSSMSGPQQLMIPQTLAQQNRERPLLLEEQ-PLLL 3055
Score = 36.6 bits (83), Expect = 0.24
Identities = 34/130 (26%), Positives = 51/130 (39%), Gaps = 18/130 (13%)
Query: 1273 MLPLPLQPPLPPPRPPRPPSPPPEPETTDASHPSVPPEPLAEDHPPHTPGLCGSLAKSQS 1332
M P + P + P P P + PP S P+ P P H HT + G S
Sbjct: 3275 MAPPTMMPSVQPQPPLIPGATPPT-----MSQPTFPMVPQQLQHQQHTTVISG----HTS 3325
Query: 1333 TETVPATPGGEPPLSGGSSGLSLSSPQVPGS----PFSYPAPSPSLSSGGLPRT---PGR 1385
+P+ PG +P + + L L+ P++ P P+P S P++ P
Sbjct: 3326 PVRMPSLPGWQP--NSAPAHLPLNPPRIQPPIAQLPIKTCTPAPGTVSNANPQSGPPPRV 3383
Query: 1386 DFSFTPTFSE 1395
+F FSE
Sbjct: 3384 EFDDNNPFSE 3393
Score = 35.0 bits (79), Expect = 0.71
Identities = 12/18 (66%), Positives = 13/18 (72%)
Query: 691 PPPPPPPPPQPGFPMPPP 708
P PPPPPP +PG P P P
Sbjct: 12 PQPPPPPPEEPGAPAPSP 29
Score = 34.3 bits (77), Expect = 1.2
Identities = 51/204 (25%), Positives = 74/204 (36%), Gaps = 41/204 (20%)
Query: 1240 SPEPPAKEVEARPPLSPERAPEHDLEVEPEPPMMLPLPLQPPLPPPRP------PRPPSP 1293
+P P + ++ P +P + + DL V P P P PRP +PP+
Sbjct: 2165 TPRPTTVDPYSQQPQTPRPSTQTDLFVTPVTNQRHSDPYAHPPGTPRPGISVPYSQPPA- 2223
Query: 1294 PPEPETTDA------SHPSVPP--EPLAEDHPPHTPGLCGSLAKSQSTETVPATPGGEPP 1345
P P ++ + P + P +P + P L G L + +T TP PP
Sbjct: 2224 TPRPRISEGFTRSSMTRPVLMPNQDPFLQAAQNRGPALPGPLVR--PPDTCSQTP--RPP 2279
Query: 1346 LSGGSSGLSLSSPQVPGSPFSYPAPSPSLSSGGL------------PRTPGRDFSFTPTF 1393
G S S SP P+ +P S PR PG + SF +
Sbjct: 2280 GPGLSDTFSRVSPSAARDPYDQSPMTPRSQSDSFGTSQTAHDVADQPR-PGSEGSFCASS 2338
Query: 1394 SEP--------SGPLLLPVCPLPT 1409
+ P SG LP P+PT
Sbjct: 2339 NSPMHSQGQQFSGVSQLP-GPVPT 2361
Score = 32.7 bits (73), Expect = 3.5
Identities = 29/91 (31%), Positives = 37/91 (40%), Gaps = 14/91 (15%)
Query: 668 AVAAPSVLAPTLPLPPPPGFPPLPPPPPPPPPQPGFPM-PPPLPPPPPPPPPAHPAVTVP 726
A+A P+++ P PP +P PP QP FPM P L + V
Sbjct: 3274 AMAPPTMMPSVQPQPPL-----IPGATPPTMSQPTFPMVPQQLQHQQHTTVISGHTSPVR 3328
Query: 727 PPPLP------APPGVP--PPPILPPLPPFP 749
P LP AP +P PP I PP+ P
Sbjct: 3329 MPSLPGWQPNSAPAHLPLNPPRIQPPIAQLP 3359
Score = 32.3 bits (72), Expect = 4.6
Identities = 36/143 (25%), Positives = 49/143 (34%), Gaps = 32/143 (22%)
Query: 625 SEKMDEGQQSSGEDMEI--SDDEMPSAPITSADCPKPMVVTPGAAAVAAPSVLAPTLPLP 682
+E+ + QQ G + S + PS+ I S P+ PG ++ L
Sbjct: 1778 NEQQQQQQQQFGSQHLLVQSGSDTPSSGIQS-----PLTPQPGNGNMSPAQSFHKEL--- 1829
Query: 683 PPPGFPPLPPPPPPPPPQPGFPMPPPLPPPPPPPPP-------AHPAVTVPPPPLPAPPG 735
F PP P + P PPPPP P + + PP P PG
Sbjct: 1830 ----FTKQPPSTPTSTSSDDVFVKPQAPPPPPAPSRIPIQDSLSQAQTSQPPSPQVFSPG 1885
Query: 736 V----PPPPILP-------PLPP 747
PP P+ P P PP
Sbjct: 1886 SSNSRPPSPMDPYAKMVGTPRPP 1908
Score = 32.0 bits (71), Expect = 6.0
Identities = 26/86 (30%), Positives = 35/86 (40%), Gaps = 6/86 (6%)
Query: 1458 PPLLPAPLASCPPPMK-RKPGRPRRSPPSMLSLDGPLVRPPAGAALGRELLLLPGQPQTP 1516
PP PA L PPPM +K + + G LV LG + LP +PQ
Sbjct: 3897 PPTPPASLPPTPPPMACQKMANGFATTEELAGKAGVLVSHEVTKTLGPKPFQLPFRPQDD 3956
Query: 1517 VFPS--THDPRTVTLDFRNAGIPAPP 1540
+ P+TV + A +P PP
Sbjct: 3957 LLARALAQGPKTVDVP---ASLPTPP 3979
Score = 31.6 bits (70), Expect = 7.8
Identities = 19/54 (35%), Positives = 22/54 (40%), Gaps = 3/54 (5%)
Query: 1537 PAPPPPLPPQPPPPPPPPPVEPTKLP--FKELDNQWPSEAIPPGPRGRDEVTEE 1588
P PPPP PP+ P P P P K P D P + PR R + E
Sbjct: 12 PQPPPP-PPEEPGAPAPSPAAADKRPRGRPRKDGASPFQRARKKPRSRGKTAVE 64
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 134 bits (337), Expect = 9e-31
Identities = 86/225 (38%), Positives = 120/225 (53%), Gaps = 25/225 (11%)
Query: 1701 TGCARSEGFYTIDKKDKLRYLNSSRASTDEPPADTQGMSIPAQPHASTRAGSERRSEQRR 1760
TGCARSE K + LNS+ S T + P S + + S+ RR
Sbjct: 5336 TGCARSEPKILTHYK-RPHTLNSTSMSKAYQSTFTGETNTPY----SKQFVHSKSSQYRR 5390
Query: 1761 LLSSFTGSCDSDLLKFNQLKFRKKKLKFCKSHIHDWGLFAMEPIAADEMVIEYVGQNIRQ 1820
L + + K + +S I GL+A + + MVIEY+G IR
Sbjct: 5391 LRTEW-----------------KNNVYLARSRIQGLGLYAAKDLEKHTMVIEYIGTIIRN 5433
Query: 1821 VIADMREKRYEDEGIGSSYMFRVDHDTIIDATKCGNFARFINHSCNPNCYAKVITVESQK 1880
+A+ REK YE++ G YMFR++++ +IDAT G AR+INHSC PNC A+V+T + +
Sbjct: 5434 EVANRREKIYEEQNRGI-YMFRINNEHVIDATLTGGPARYINHSCAPNCVAEVVTFDKED 5492
Query: 1881 KIVIYSKQHINVNEEITYDYKFPIED--VKIPCLCGSENCRGTLN 1923
KI+I S + I EE+TYDY+F ED KIPC CG+ NCR +N
Sbjct: 5493 KIIIISSRRIPKGEELTYDYQFDFEDDQHKIPCHCGAWNCRKWMN 5537
Score = 100 bits (249), Expect = 1e-20
Identities = 150/572 (26%), Positives = 218/572 (38%), Gaps = 120/572 (20%)
Query: 366 PPFKAQPQDSATFAHTPPPAQATPAPGFKSAFSP-----------YQTPVAHFPPPPEEP 414
PP ++ P + PP ++ P+P ++ SP ++P++ PPP E P
Sbjct: 505 PPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLS--PPPEELP 562
Query: 415 TATAAFGARDSGEFRRAPAPPP------LPPAE-----PLAKEKPGTPPGP-----PPPD 458
T+ +R S +P PP PP E P +E P +PP PPP+
Sbjct: 563 TSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPE 622
Query: 459 TNSMELGGRPTFGWSPEPCDSPGTPTLESSPAGPEKPHDSLDSRIEMLLKEQRTKLLFLR 518
+ + SP P DSP +P E SP P P S S + ++ + L
Sbjct: 623 ASRL----------SPPPEDSPMSPPPEESPMSPP-PEVSRLSPLPVVSR--------LS 663
Query: 519 EPDSDTELQM--EGSPISS--SSSQLSPLAPFGTNSQPGFRGPT--PPSSRPSSTGLEDI 572
P ++ L E SP S +S+LSP S P P PP S LE+
Sbjct: 664 PPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEES 723
Query: 573 SPTPLPDSDEDEELDLG--LGPRPPP---EPGPPDP--------AGLLSQTAEVALDLVG 619
PLP+ + G L PRP P P +P L Q E L V
Sbjct: 724 PLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVP 783
Query: 620 DRTPTSEKMDEGQQSSGEDMEI----SDDEMPSAPITSADCPKPMVVTPGAAAVAAPSVL 675
+ P EG S + E+ +E +P+ C P + + L
Sbjct: 784 EE-PHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCL 842
Query: 676 APTLP---LPPPPGFPPLPPPPPPPPPQPG-FPMPPPLPPPPPPPPPA------HPAVTV 725
+P L P PPL P P PP +PG P P LP PPP P+ PA++
Sbjct: 843 SPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSE 902
Query: 726 P--PP--PLP-------------APPGVPPPPILPPLPPF-----PPGLFPVMQVDMSHV 763
P PP PLP +P +PP P+ PPL P PP L P+ +++ +
Sbjct: 903 PGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGELE--YP 960
Query: 764 LGGQWGGMPMSFQMQTQVLSRLMT--GQGAC----PYPPFMAAAAAAASAG----LQFVN 813
G + P S + +L ++ + C P PP + + + G +
Sbjct: 961 FGAKGDSDPES-PLAAPILETPISPPPEANCTDPEPVPPMILPPSPGSPVGPASPILMEP 1019
Query: 814 LPPYRGPFSLSNSGPGRGQHWPPLPKFDPSVP 845
LPP P + P Q+ PP P++P
Sbjct: 1020 LPPQCSPLLQHSLVP---QNSPPSQCSPPALP 1048
Score = 98.2 bits (243), Expect = 7e-20
Identities = 176/656 (26%), Positives = 223/656 (33%), Gaps = 101/656 (15%)
Query: 1014 PKGVGVRRRPARPLELDSGGEEDEKES-LSEEQESTEEEEEAEEEEEEEDDDDDDSDDRD 1072
PK G + A+PL E + E+ L+EE EE+ E+ +
Sbjct: 406 PKEPGPLQCEAKPLGKAGVQLEPQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEAS 465
Query: 1073 ESENDDEDTALSEASEKDEGDSDEEETVSIVTSKAEATSSSESSESSEFESSSESSPSSS 1132
E+ S E EE S ++ E + S ESS F ES S
Sbjct: 466 RLSPPPEELPASPLPEALHLSRPLEE--SPLSPPPEESPLSPPPESSPFSPLEESPLSPP 523
Query: 1133 EDEEEVVAREEEEEEEEEEMVA----EESMASAGPEDFEQDGEEAALAPGAPAVDSLGME 1188
E+ A E E EES S PE+ P +P ++ +
Sbjct: 524 EESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEEL----------PTSPPPEASRLS 573
Query: 1189 EEVDIETEAVAPEERPSMLDEPP-----LPVGVEEPADSREPPEEPGLSQEGAMLLSPEP 1243
+ + PEE P + PP P E P PPEE LS P P
Sbjct: 574 PPPEESPMSPPPEESP--MSPPPEASRLFPPFEESPLSP--PPEESPLS--------PPP 621
Query: 1244 PAKEVEARPPLSPERAPEHDLEVEPEPPM--MLPLPLQPPLPPPRPPRPPSPPPEPETT- 1300
A + P SP P + + P P + + PLP+ L PP P SPPPE T
Sbjct: 622 EASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTS 681
Query: 1301 ---DASHPSVPPE-----PLAEDHPPHTPGLCGSLAKSQSTETVPATP-GGEPPLSGGSS 1351
+AS S PPE P ED P P + S E P P EP L S
Sbjct: 682 PPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLM--SLPLEESPLLPLPEEPQLCPRSE 739
Query: 1352 GLSLSSPQVPGSPFSYPAPS-PSLSSGGLPRTPGRDFSFTPTFSEPSGPLLLPVCPLPTG 1410
G LS P P P P P LS P+ S +P P L V P
Sbjct: 740 GPHLSPR--PEEPHLSPRPEEPHLS----PQAEEPHLS-----PQPEEPCLCAV-PEEPH 787
Query: 1411 RRDERSGPLASPVLLETGL------PLPLPLPLPLPLALPAVLRAQARAPTPLPPLLPAP 1464
+ GP SP E L P P+P P P + + P L P P
Sbjct: 788 LSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEE-PCLSPQPEESHLSPQSEEPCLSPRP 846
Query: 1465 LASC------PPPMKRKPGRPRRSP-----PSMLSLDGPLVRPPAGAALGRELLLLPGQP 1513
S PP+ +P +P P P L L P P LG L PG+P
Sbjct: 847 EESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEP 906
Query: 1514 QTPVFPSTHDPRTVTLDFRNAGIPAPPPPLPPQPPPPPPPPPV-----EPTKLPFKELDN 1568
P L +G P+ P L P P PPP P+ P P EL+
Sbjct: 907 PLSPLPEE-------LPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGELE- 958
Query: 1569 QWPSEAIPPGPRGRDEVTEEYMELAKSRGPWRRPPKKRHEDLVPPAGSPELSPPQP 1624
P G +G D E + P PP+ D P P + PP P
Sbjct: 959 ------YPFGAKG-DSDPESPLAAPILETPISPPPEANCTD--PEPVPPMILPPSP 1005
Score = 97.4 bits (241), Expect = 1e-19
Identities = 126/434 (29%), Positives = 164/434 (37%), Gaps = 59/434 (13%)
Query: 1219 PADSREPPEEPG---LSQEGAMLLS--PEPPAKEVEARPPLSP-----ERAPEHDLEVEP 1268
P SR P EPG + A+ ++ +P V + P P E P V+
Sbjct: 367 PVCSRFSPPEPGDTPTDEPDALYVACQGQPKGGHVTSMQPKEPGPLQCEAKPLGKAGVQL 426
Query: 1269 EPPMMLPLPLQPPLPPPRPPRPPSPPPEPETT----DASHPSVPPEPLAEDHPPHTPGLC 1324
EP + PL + PL PP P SPPPE T +AS S PPE L P L
Sbjct: 427 EPQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLS 486
Query: 1325 GSLAKSQSTETVPATPGGEPPLSGGSSGLSLSSPQVPGSPFSYPAPSPSLSSGGLPRTPG 1384
L +S + +P PP S S L S P SP PSP+L + P +P
Sbjct: 487 RPLEESPLSPPPEESPLSPPPESSPFSPLEES----PLSPPEESPPSPALET---PLSPP 539
Query: 1385 RDFS-FTPTFSEPSGPLLLPVCPLPTGRRDERSGPLASPVLLETGLPLPLPLPLPLPLAL 1443
+ S +P F E PL P LPT E S L+ P P P P+ P
Sbjct: 540 PEASPLSPPFEE--SPLSPPPEELPTSPPPEAS-RLSPPPEESPMSPPPEESPMSPPPEA 596
Query: 1444 PAVLRAQARAPTPLPPLLPAPLASCPPPMKRKPGRPRRSPPSMLSLDGPLVRPPAGAALG 1503
+ +P PP +PL S PP R P SP S + P+ PP + L
Sbjct: 597 SRLFPPFEESPLS-PPPEESPL-SPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLS 654
Query: 1504 RELL---LLPGQPQTPVFPSTHDPRTVTLDFRNAGIPAPPPPL-----PPQPPPPPPPPP 1555
+ L P ++P+ P + T +PPP PP+ P PPP
Sbjct: 655 PLPVVSRLSPPPEESPLSPPPEESPT-----------SPPPEASRLSPPPEDSPTSPPPE 703
Query: 1556 VEPTKLPFKELDNQWPSEAIPPGPRGRDEVTEEYMELAKSRGPWRRP--------PKKRH 1607
P P ++ P E P P + EE +S GP P P+
Sbjct: 704 DSPASPPPEDSLMSLPLEESPLLP-----LPEEPQLCPRSEGPHLSPRPEEPHLSPRPEE 758
Query: 1608 EDLVPPAGSPELSP 1621
L P A P LSP
Sbjct: 759 PHLSPQAEEPHLSP 772
Score = 94.0 bits (232), Expect = 1e-18
Identities = 160/598 (26%), Positives = 205/598 (34%), Gaps = 99/598 (16%)
Query: 1037 EKESLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDESENDDEDTALSEASEKDEGDSDE 1096
E+ LS E + E ++ S + + +T LS E
Sbjct: 490 EESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPF 549
Query: 1097 EETVSIVTSKAEATSSSESSESSEFESSSESSPSSSEDEEEVVAREEEE-------EEEE 1149
EE S ++ E +S E+S E SP S EE ++ E EE
Sbjct: 550 EE--SPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESP 607
Query: 1150 EEMVAEESMASAGPED--FEQDGEEAALAPGAPAVDSLGMEEEVDIETEAVAPEERPSML 1207
EES S PE E++ ++P P + EV ++P S L
Sbjct: 608 LSPPPEESPLSPPPEASRLSPPPEDSPMSP-PPEESPMSPPPEVS----RLSPLPVVSRL 662
Query: 1208 DEPPLPVGVEEPADSREPPEEPGLSQEGAMLLSPEPPAKEVEARPPLSPERAPEHD---- 1263
PP EE S P E P A LSP P P SP P D
Sbjct: 663 SPPP-----EESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMS 717
Query: 1264 LEVEPEPPMMLPLPLQPPLPP--------PRP------PRPPSPPPEPETTDASHPSVPP 1309
L +E P +LPLP +P L P PRP PRP P P+ + P
Sbjct: 718 LPLEESP--LLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPE 775
Query: 1310 EPLA-----EDH------PPHTPGLCGSLAKSQSTETVPATPGGEPPLSGGSSGLSLSSP 1358
EP E H PH L S TE +P E P S SP
Sbjct: 776 EPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSP 835
Query: 1359 QVPGSPFSYPAPSPSLSSGGLPRTPGRDFSFTPTFSEPS---GPLLLPVCPLPTGRRDER 1415
Q P P P S S L + P P EP P LP+ P P
Sbjct: 836 QSE-EPCLSPRPEESHLSPELEKPPLSPRPEKPP-EEPGQCPAPEELPLFPPPG--EPSL 891
Query: 1416 SGPLASPVLLETGLPLPLPLPLPLPLALPAV--LRAQARAPTPLPP-LLPAPLASCPP-- 1470
S L P L E G P PLP LPL+ L Q P PLPP L P A+ PP
Sbjct: 892 SPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPAL 951
Query: 1471 --------PMKRKPGRPRRSPPSMLSLDGPLVRPPAGAALGREL---LLLPGQPQTPVFP 1519
P K SP + L+ P+ PP E ++LP P +PV P
Sbjct: 952 SPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPGSPVGP 1011
Query: 1520 STHDPRTVTLDFRNAGIPAPPPPLPPQPPPPPPPPPVEPTKLPFKELDNQWPSEAIPP 1577
++ P+ +P PP P ++ + +P N PS+ PP
Sbjct: 1012 AS--------------------PILMEPLPPQCSPLLQHSLVP----QNSPPSQCSPP 1045
Score = 82.0 bits (201), Expect = 5e-15
Identities = 99/353 (28%), Positives = 121/353 (34%), Gaps = 65/353 (18%)
Query: 410 PPEEPTA--TAAFGARDSGEFRRAPAPPPLP---PAEPLAKEKPGTPPGPPPPDTNSMEL 464
P +EP A A G G P P A+PL K P P M L
Sbjct: 381 PTDEPDALYVACQGQPKGGHVTSMQPKEPGPLQCEAKPLGKAGVQLEPQLEAPLNEEMPL 440
Query: 465 GGRPTFGWSPEPCDSPGTPTLESSPAGPEKPHDSLDSRIEMLLKEQRTKLLFLREPDSDT 524
P P +SP +P E SP P L E L + L L P
Sbjct: 441 --------LPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRP---- 488
Query: 525 ELQMEGSPISSSSSQLSPLAPFGTNSQPGFRGPTPPSSRPSSTGLEDISPTPLPDSDEDE 584
+E SP+S + SPL+P PP S P S LE+ +P +S
Sbjct: 489 ---LEESPLSPPPEE-SPLSP-------------PPESSPFSP-LEESPLSPPEESPPSP 530
Query: 585 ELDLGLGPRPPPEP-GPPDPAGLLSQTAEVALDLVGDRTPTSEKMDEGQQSSGEDMEISD 643
L+ L P P P PP LS P E++ +
Sbjct: 531 ALETPLSPPPEASPLSPPFEESPLS--------------PPPEELPTSPPPEASRLSPPP 576
Query: 644 DEMPSAPITSADCPKPMVVTPGAAAVAAPSVLAPTLPLPPPPGFPPLPPPPP----PPPP 699
+E P +P PM P A+ + P PL PPP PL PPP PPP
Sbjct: 577 EESPMSPPPE---ESPMSPPPEASRLFPP---FEESPLSPPPEESPLSPPPEASRLSPPP 630
Query: 700 QPGFPMPPPLPPPPPPPPPAH-----PAVTVPPPPLPAPPGVPPPPILPPLPP 747
+ PPP P PPP P V+ PP P PPP P PP
Sbjct: 631 EDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPP 683
Score = 82.0 bits (201), Expect = 5e-15
Identities = 129/477 (27%), Positives = 176/477 (36%), Gaps = 90/477 (18%)
Query: 1108 EATSSSESSESSEFESSSESSPSSSEDEEEVVAREEEEEE-----EEEEMVA-------- 1154
EA+ S E S E SP+S E+ +++ EE EE ++
Sbjct: 685 EASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLS 744
Query: 1155 ---EESMASAGPED--FEQDGEEAALAPGAPAVDSLGMEEEVDIETEAVAPEERPSMLDE 1209
EE S PE+ EE L+P + EE + +A P P +E
Sbjct: 745 PRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQP-EE 803
Query: 1210 PPLPVGVEEPADSREPPEEPGLSQEGAMLLSPEPPAKEVEARPPLSPERAPEHDLEVEPE 1269
L EEP S PEEP LS + PE ++ P R E L E E
Sbjct: 804 LHLSPQTEEPHLS-PVPEEPCLSPQ------PEESHLSPQSEEPCLSPRPEESHLSPELE 856
Query: 1270 PPMMLPLPLQPPLPPPRPPRPPSPPPEPETTDASHPSVPPEPLAEDHPPHTPGLCGSLAK 1329
P + P P +PP P + P P P P PP P L L +
Sbjct: 857 KPPLSPRPEKPPEEPGQCPAPEELPLFP-------------------PPGEPSLSPLLGE 897
Query: 1330 SQSTETVPATPGGEPPLSGGSSGLSLSSPQVPGSPFSYPAPSPSLSSGGLPRTPGRDFSF 1389
+E GEPPLS L LS P+ PSLS +P P
Sbjct: 898 PALSEP------GEPPLSPLPEELPLS-----------PSGEPSLSPQLMPPDP-LPPPL 939
Query: 1390 TPTFSEPSGPLLLPVCPL--PTGRR--DERSGPLASPVLLETGLPLPLPL----PLPLPL 1441
+P + + P L P+ L P G + + PLA+P+ LET + P P P+P
Sbjct: 940 SPIITAAAPPALSPLGELEYPFGAKGDSDPESPLAAPI-LETPISPPPEANCTDPEPVP- 997
Query: 1442 ALPAVLRAQARAPT-PLPPLLPAPLASCPPPMKRKPGRPRRSPPSM-----LSLDGPLVR 1495
P +L +P P P+L PL P+ + P+ SPPS L L P
Sbjct: 998 --PMILPPSPGSPVGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSPL 1055
Query: 1496 PPAGAALG----RELLLLP----GQPQTPVF-PSTHDPRTVTLDFRNAGIPAPPPPL 1543
P G +G EL + +P+ P PS P + + P+P P L
Sbjct: 1056 SPIGKVVGVSDEAELHEMETEKVSEPECPALEPSATSPLPSPMGDLSCPAPSPAPAL 1112
Score = 78.6 bits (192), Expect = 6e-14
Identities = 107/389 (27%), Positives = 140/389 (35%), Gaps = 92/389 (23%)
Query: 382 PPPAQATPAPGFKSAFSPYQTPVAHFPPPPEE-PTATAAFGARDSGEFRRAPAPPPLPPA 440
PPP ++ +P + + + + PPPEE P + PLP A
Sbjct: 442 PPPEESPLSPPPEESPTSPPPEASRLSPPPEELPAS-------------------PLPEA 482
Query: 441 EPLAKEKPGTPPGPPPPDTNSMELGGRPTFGWSPEPCDSPGTPTLESSPAGPEKPHDSLD 500
L++ +P PPP ++ SP P SP +P LE SP P P +S
Sbjct: 483 LHLSRPLEESPLSPPPEES-----------PLSPPPESSPFSP-LEESPLSP--PEESPP 528
Query: 501 SRIEMLLKEQRTKLLFLREPDSDTELQ--MEGSPISSSSSQLSPLAPFGTNSQPGFRGPT 558
S P +T L E SP+S + SPL+P
Sbjct: 529 S------------------PALETPLSPPPEASPLSPPFEE-SPLSP------------- 556
Query: 559 PPSSRPSSTGLEDISPTPLPDSDEDEELDLGLGPRPPPEPGPPDPAGLLSQTAEVALDLV 618
PP P+S E +P P EE + P P PP+ + L E L
Sbjct: 557 PPEELPTSPPPEASRLSPPP-----EESPMSPPPEESPMSPPPEASRLFPPFEESPLSPP 611
Query: 619 GDRTPTSEKMDEGQQSSGEDMEISDDEMPSAPITSADCPKPMVVTPGAAAVAAPSVLAP- 677
+ +P S + + S + D M P S P P V V S L+P
Sbjct: 612 PEESPLSPPPEASRLSPPPE----DSPMSPPPEESPMSPPPEVSRLSPLPVV--SRLSPP 665
Query: 678 --TLPLPPPPGFPPLPPPPP----PPPPQPGFPMPPPLPPPPPPPPP----AHPAVTVPP 727
PL PPP P PPP PPP+ PPP P PPP + P P
Sbjct: 666 PEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPL 725
Query: 728 PPLPAPPGVPPPPILPPLPPFP--PGLFP 754
PLP P + P P L P P P L P
Sbjct: 726 LPLPEEPQLCPRSEGPHLSPRPEEPHLSP 754
Score = 78.2 bits (191), Expect = 7e-14
Identities = 189/854 (22%), Positives = 271/854 (31%), Gaps = 151/854 (17%)
Query: 548 TNSQPGFRGPTPPSSRPSSTGLEDISPTPLPDSDEDEELDLGLGPRPPPEPGPPDPAGLL 607
T+ QP GP ++P G + P ++ +EE+ L PPPE P P
Sbjct: 402 TSMQPKEPGPLQCEAKP--LGKAGVQLEPQLEAPLNEEMPL----LPPPEESPLSPPP-- 453
Query: 608 SQTAEVALDLVGDRTPTSEKMDEGQQSSGEDMEISDDEMPSAPITSA-DCPKPMVVTPGA 666
+ +PTS + + S +E+P++P+ A +P+ +P
Sbjct: 454 ------------EESPTSPPPEASRLSP------PPEELPASPLPEALHLSRPLEESP-- 493
Query: 667 AAVAAPSVLAPTLPLPPPPGFPPLPPPPPPPPPQPGFPMPPPLPPPPPPPPPAHPAVTVP 726
++ P +P P P F PL P PP + P P L P PPP A P
Sbjct: 494 --LSPPPEESPLSPPPESSPFSPLEESPLSPPEES--PPSPALETPLSPPPEASPL---- 545
Query: 727 PPPLPAPPGVPPPPILPPLPPFPPGLFPVMQVDMSHVLGGQWGGMPMSFQMQTQVLSRLM 786
PP P PPP LP PP P + + PMS + SRL
Sbjct: 546 SPPFEESPLSPPPEELPTSPP--PEASRLSPPPEESPMSPPPEESPMSPPPEA---SRL- 599
Query: 787 TGQGACPYPPFMAAAAAAASAGLQFVNLPPYRGPFSLSNSGPGRGQHWPPLPKFDPSVPP 846
+PPF + + PP P S P P P+ P PP
Sbjct: 600 -------FPPFEESPLSP----------PPEESPLS----PPPEASRLSPPPEDSPMSPP 638
Query: 847 PGYMPRQEDPHKATVDGVLLVVLKELKAIMKRDLNRKMVEVVAFRAFDEWWDKKERMAKA 906
P P P + + L V+ L + E E
Sbjct: 639 PEESPMSPPPEVSRLSP--LPVVSRLSPPPEESPLSPPPEESPTSPPPE---ASRLSPPP 693
Query: 907 SLTPVKSGEHKDEDRPKPKDRIASCLLESWGKGEGLGYEGLGLGIGLRGAIRLPSFK--V 964
+P P P+D + S LE + LP
Sbjct: 694 EDSPTSPPPEDSPASPPPEDSLMSLPLEE------------------SPLLPLPEEPQLC 735
Query: 965 KRKEPPDTTSSGDQKRLRPSTSVDEEDEESERERDRDMADTPCELAKRD-----PKGVGV 1019
R E P + ++ L P ++E + PC A + P+ G
Sbjct: 736 PRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGP 795
Query: 1020 RRRPA-RPLELDSGGEEDEKESLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDESENDD 1078
P L L EE + EE + + EE+ + E+ + +
Sbjct: 796 HLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPEL 855
Query: 1079 EDTALSEASEK---DEGDSDEEETVSIVTSKAEATSSSESSESSEFESSSESSPSSSEDE 1135
E LS EK + G E + + E + S E + S P S
Sbjct: 856 EKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPA---LSEPGEPPLSPLP 912
Query: 1136 EEVVAREEEEEEEEEEMVAEESM--------ASAGPEDFEQDGE-------EAALAPGAP 1180
EE+ E +++ + + +A P GE + P +P
Sbjct: 913 EELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGELEYPFGAKGDSDPESP 972
Query: 1181 AVDSLGMEEEVDIETEA--VAPEERPSML--DEPPLPVGVEEPA--DSREPPEEPGLSQE 1234
+ +E + EA PE P M+ P PVG P + P P L
Sbjct: 973 LAAPI-LETPISPPPEANCTDPEPVPPMILPPSPGSPVGPASPILMEPLPPQCSPLLQHS 1031
Query: 1235 GAMLLSP----EPPAKEVEARPPLSP--------ERAPEHDLEVE----PEPPMMLPLPL 1278
SP PPA + PLSP + A H++E E PE P + P
Sbjct: 1032 LVPQNSPPSQCSPPALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECPALEPSAT 1091
Query: 1279 QPPLPPPRPPRPPSPPPEPETTDASHPSVPPEPL-------AEDHPPHTPG-----LCGS 1326
P P P+P P P D S PL ++ P TPG L GS
Sbjct: 1092 SPLPSPMGDLSCPAPSPAPALDDFSGLGEDTAPLDGIDAPGSQPEPGQTPGSLASELKGS 1151
Query: 1327 LAKSQSTETVPATP 1340
E P TP
Sbjct: 1152 PVLLDPEELAPVTP 1165
Score = 73.9 bits (180), Expect = 1e-12
Identities = 144/586 (24%), Positives = 204/586 (34%), Gaps = 93/586 (15%)
Query: 241 SSVTPNSGGTPFSQ-DTAYSSCRLDTPNSYGQGTPLTPRL-GTPFSQDSSYSSRQPTPSY 298
S ++P +PFS + + S ++P S TPL+P +P S S P P
Sbjct: 501 SPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEE 560
Query: 299 LFSQDPAVTFKARRHESKFTDAYNRRHEHHYVHNSPAVTAVAGATAAFRGSSDLPFGAVG 358
L + P S+ + SP ++ A+ F + P
Sbjct: 561 LPTSPPP-------EASRLSPPPEESPMSPPPEESP-MSPPPEASRLFPPFEESPLSPPP 612
Query: 359 GTGGSSGPPFKAQ----PQDSATFAHTPPPAQATPAPGFK-SAFSPYQTPVAHFPPPPEE 413
S PP ++ P+DS +PPP ++ +P + S SP PPP E
Sbjct: 613 EESPLSPPPEASRLSPPPEDSPM---SPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEES 669
Query: 414 PTATAAFGARDSG--EFRRAPAPPPLPPAEPLAKEKPGTPPGPPPPDTNSMELGGRPTFG 471
P + + S E R PP P P ++ P +PP P S+ L P
Sbjct: 670 PLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPP--PEDSLMSLPLEESPLLP 727
Query: 472 WSPEP--CDSPGTPTLESSPAGP------EKPHDSLDSRIEMLLKEQRTKLLFLREPDSD 523
EP C P L P P E+PH S + L + L +
Sbjct: 728 LPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPH 787
Query: 524 TELQMEGSPISSSSSQLSPLAPFGTNSQPGFRGPTPP----SSRPSSTGL----EDISPT 575
Q EG +S +L L+P ++ P P S +P + L E+ +
Sbjct: 788 LSPQAEGPHLSPQPEELH-LSP---QTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLS 843
Query: 576 PLPD----SDEDEELDLGLGP-RPPPEPG------------PPDPAGLLSQTAEVALDLV 618
P P+ S E E+ L P +PP EPG PP L E AL
Sbjct: 844 PRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEP 903
Query: 619 GDRTPTSEKMDEGQQSSGEDMEISDDEMPSAPITSADCPKPMVVTPGAAA---------- 668
G+ P S +E S + +S MP P+ P P A +
Sbjct: 904 GE-PPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGELEYPFG 962
Query: 669 ----------VAAPSVLAPTLPLP------PPPGFPPLPPPPPPPPPQPGFPMPPPLPPP 712
+AAP + P P P P P P + PP P P P P+
Sbjct: 963 AKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPGSPVGPASPI-----LM 1017
Query: 713 PPPPPPAHPAVTVPPPPLPAPPGVPPPPILPPLPPFPPGLFPVMQV 758
P PP P + P +PP PP LP P P L P+ +V
Sbjct: 1018 EPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSP--LSPIGKV 1061
Score = 69.3 bits (168), Expect = 3e-11
Identities = 113/450 (25%), Positives = 144/450 (32%), Gaps = 40/450 (8%)
Query: 1200 PEERPSM-LDEPPLPVGVEEPADSREPPEEPGLSQEGAMLLSPEPPAKEVEARPPLSPER 1258
P P++ + P P G+ AD P P S G P+ P + PP P +
Sbjct: 2118 PAAAPTIFIGSPTTPAGLSTSADGFLKP--PAGSVPG-----PDSPGELFLKLPPQVPAQ 2170
Query: 1259 APEHD-LEVEPEPPMMLPLPLQPPLPPPRPPRPPSPPPEPETTDASHPSVPPEPLAEDHP 1317
P D + P P+ P PP PP P +P P +S P P
Sbjct: 2171 VPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPGAGQPGEFHTTP 2230
Query: 1318 PHTPGLCGSLAKSQSTETVPATPGGEPPLSGGSSGLSLSSPQVPGSPFSYPAPSPSLSSG 1377
P TP S P+ P S G G S P + PF + +
Sbjct: 2231 PGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPPFGESRKALEVKKE 2290
Query: 1378 GLPRT------PGRDFSFTPTFSEPSGPLLL---PVCPLPTGRRDERSGPLASPVLLETG 1428
L + P F +P+ G L L V P R + P + + L
Sbjct: 2291 ELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQ 2350
Query: 1429 LPLPLPLPLPLPLALPAVLRAQARA-PTPLPPLLPAPLASCPPPMKRKPGRPRRSPPSML 1487
P P P P + P + R + P PPL P P PPP + P RS PS
Sbjct: 2351 EPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQ---PPPPESCCALPPRSLPS-- 2405
Query: 1488 SLDGPLVRPPAG--AALGRELLLLPGQPQTPVF-PSTHDPRTVTLD--FRNAGIPAPPPP 1542
P R PA + + L P F PS PR + D R P P
Sbjct: 2406 ---DPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDP 2462
Query: 1543 LPPQPPPPPPPPPVEPTK---LPFKELDNQWPSEAIPPGPRGR-----DEVTEEYMELAK 1594
P PP P PP K L L A+P GP G +
Sbjct: 2463 FAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQPPNFVRSP 2522
Query: 1595 SRGPWRRPPKKRHEDLVPPAGSPELSPPQP 1624
G + P G P L PP P
Sbjct: 2523 GTGAFVGTPSPMRFTFPQAVGEPSLKPPVP 2552
Score = 63.2 bits (152), Expect = 2e-09
Identities = 106/428 (24%), Positives = 144/428 (33%), Gaps = 76/428 (17%)
Query: 372 PQDSATFAHTPPPAQATPAPGFKSAFSPYQTPVAHFPPPPEEPTATAAFGARDSGEFRRA 431
P+DS T +PPP + +P + + + P PEEP
Sbjct: 693 PEDSPT---SPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEE 749
Query: 432 PAPPPLPPAEPLAK--EKPGTPPGPPPP-------DTNSMELGGRPTFGWSPEPCD-SPG 481
P P P L+ E+P P P P + + P PE SP
Sbjct: 750 PHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQ 809
Query: 482 TPTLESSPAGPEKPHDSLDSRIEMLLKEQRTKLLFLREPDSDTELQMEGSPISSSSSQLS 541
T SP PE+P S L + L R +S ++E P+S +
Sbjct: 810 TEEPHLSPV-PEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEK-P 867
Query: 542 PLAPF---GTNSQPGFRGPTPPSSRP-------SSTGLEDISPTP--LPDSDEDEELDLG 589
P P P F P PS P S G +SP P LP S E
Sbjct: 868 PEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEP---S 924
Query: 590 LGPR-PPPEPGPPDPAGLLSQTAEVALDLVGD-RTPTSEKMDEGQQS--SGEDMEISDDE 645
L P+ PP+P PP + +++ A AL +G+ P K D +S + +E
Sbjct: 925 LSPQLMPPDPLPPPLSPIITAAAPPALSPLGELEYPFGAKGDSDPESPLAAPILETPISP 984
Query: 646 MPSAPITSADCPKPMVVTPGAAAVAAPSVLAPTLPLPPPPGFPPL---------PPPPPP 696
P A T + PM++ P + P+ +P L P PP PL PP
Sbjct: 985 PPEANCTDPEPVPPMILPPSPGSPVGPA--SPILMEPLPPQCSPLLQHSLVPQNSPPSQC 1042
Query: 697 PPPQPGFPMPPPLPP---------------------PPPPPPPAHPAVTVP--------- 726
PP +P PL P P P P+ T P
Sbjct: 1043 SPPALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECPALEPSATSPLPSPMGDLS 1102
Query: 727 -PPPLPAP 733
P P PAP
Sbjct: 1103 CPAPSPAP 1110
Score = 62.8 bits (151), Expect = 3e-09
Identities = 136/540 (25%), Positives = 182/540 (33%), Gaps = 131/540 (24%)
Query: 340 AGATAAFRGSSDLPFGAVGGTGGSSGPPFKAQPQDSAT---FAHTPP--PAQATPAPGFK 394
A A F GS P G G PP + P + F PP PAQ F
Sbjct: 2119 AAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDSPGELFLKLPPQVPAQVPSQDPFG 2178
Query: 395 SAFSPYQTPVAHFPPPPEEPTATAAFGARDSGEFRRAPAPPPLPPAEPL-AKEKPG---- 449
A + +P P PTA + S APA PP+ A +PG
Sbjct: 2179 LAPA--------YPLEPRFPTAPPTYPPYPSPT--GAPAQPPMLGASSRPGAGQPGEFHT 2228
Query: 450 TPPGPPPPDTNSMELGGRPTFGWSPEPCDSPGTPTLESSPAGPEKPHDSLDSRIEMLLKE 509
TPPG P ++ P+P P P+L++ A PE P E LL
Sbjct: 2229 TPPGTPRHQPST------------PDPFLKPRCPSLDNL-AVPESPGVGGGKASEPLLSP 2275
Query: 510 QRTKLLFLREPDSDTELQMEGSPISSSSSQLSPLAPFGTNSQPGFRGPTPPSSRPSSTGL 569
+S L+++ + +SS P P PSS GL
Sbjct: 2276 PPFG-------ESRKALEVKKEELGASSPSYGP---------PNLGFVDSPSSGTHLGGL 2319
Query: 570 E----DISPTPL-PDSDEDEELDLGLGPRPPPEPGPPDPAGLLSQTAEVALDLVGDRTPT 624
E D+ PL P + + E GLG RP P PA L+ + D+ + T
Sbjct: 2320 ELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEPP----PAQALAPSPPSHPDIFRPGSYT 2375
Query: 625 SEKMDEGQQSSGEDMEISDDEMPSAPITSADCPKPMVVTPGAAAVAAPSVLAPTLPLPPP 684
D P+T P+P P + P L P+ P
Sbjct: 2376 -------------------DPYAQPPLT----PRPQPPPPESCCALPPRSL-PSDPFSRV 2411
Query: 685 PGFP--------PLPPPPP------PPPPQPGFPMPPPLPPPPPPPPPAHPAVTVPPPPL 730
P P PL P P P P P F P P PP P P + PP
Sbjct: 2412 PASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPPR 2471
Query: 731 PAPPGVPPPPILPPLPPFPPGLFPVMQVDMSHVLGGQWGGMPMSFQM--QTQVLSRLMTG 788
P PP V F G ++H G GG P + ++ +++ +G
Sbjct: 2472 PQPPEV----------AFKAG-------SLAHTSLGA-GGFPAALPAGPAGELHAKVPSG 2513
Query: 789 QGACPYPPFMAAAAAAASAGLQFVNLP-PYRGPFSLSNSGPGRGQHWPPLPKFDPSVPPP 847
Q P F+ + A FV P P R F + P PP+P+ P +PPP
Sbjct: 2514 QP----PNFVRSPGTGA-----FVGTPSPMRFTFPQAVGEPSLK---PPVPQ--PGLPPP 2559
Score = 61.2 bits (147), Expect = 9e-09
Identities = 77/290 (26%), Positives = 96/290 (33%), Gaps = 41/290 (14%)
Query: 1348 GGSSGLSLSSPQVPG-SPFSYPAPSPSLSSGGLPRTPGRDFSFTPTFSEPSGPLLLPVCP 1406
GG + S++ P S FS P P G P T D + +P G + + P
Sbjct: 354 GGQTIRSVAEQHTPVCSRFSPPEP------GDTP-TDEPDALYVACQGQPKGGHVTSMQP 406
Query: 1407 LPTGRRDERSGPLASP-VLLETGLPLPLPLPLPLPLALPAVLRAQARAPTPLPPLLPAPL 1465
G + PL V LE L PL +PL LP + P P P P
Sbjct: 407 KEPGPLQCEAKPLGKAGVQLEPQLEAPLNEEMPL---LPPPEESPLSPPPEESPTSPPPE 463
Query: 1466 AS-CPPPMKRKPGRPRRSPPSMLSLDGPLVRPPAGAALGRELLLLPGQPQTPVFPSTHDP 1524
AS PP + P P P L L PL P L P ++P+ P
Sbjct: 464 ASRLSPPPEELPASPL---PEALHLSRPLEESP----------LSPPPEESPLSPPPESS 510
Query: 1525 RTVTLDFRNAGIPAPPPPLPPQPPPPPPPPPVEPTKLPFKELDNQWPSEAIPPGPRGRDE 1584
L+ P PP P P PPP P PF+E P E +P P
Sbjct: 511 PFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEAS 570
Query: 1585 VTEEYMELAKSRGPWRRPPKKRHEDLVPPAGSPELSPPQPLFRPRSEFEE 1634
R P + PP +SPP R FEE
Sbjct: 571 ---------------RLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEE 605
Score = 61.2 bits (147), Expect = 9e-09
Identities = 120/463 (25%), Positives = 165/463 (35%), Gaps = 74/463 (15%)
Query: 1175 LAPGAPAVDSLGMEEEVDIET-EAVAPEERPSMLDEP--PLPVGVEEPADSREPPEEPGL 1231
L P P++D+L + E + +A P P E L V EE S P L
Sbjct: 2245 LKPRCPSLDNLAVPESPGVGGGKASEPLLSPPPFGESRKALEVKKEELGASSPSYGPPNL 2304
Query: 1232 S-----QEGAMLLSPEPPAKEVEARPPLSPERAPEHDLEVEPEPPMMLPLPLQPPLPPPR 1286
G L E +V + PL+P + +VEP+ P + P +PP
Sbjct: 2305 GFVDSPSSGTHLGGLELKTPDV-FKAPLTPRAS-----QVEPQSPGLGLRPQEPPPAQAL 2358
Query: 1287 PPRPPSPP----PEPETTDASHPSVPPEPLAEDHPPHTPGLCGSLAKSQSTE---TVPAT 1339
P PPS P P T + P + P P PP C +S ++ VPA+
Sbjct: 2359 APSPPSHPDIFRPGSYTDPYAQPPLTPRP----QPPPPESCCALPPRSLPSDPFSRVPAS 2414
Query: 1340 PGGEPPLSGGSSGLSLSSPQVPGSPFSYPAPSPSLSSGGLPRTPGRDFSFTPTFSEPSGP 1399
P + + LS+ SP + SP S R P R P +P P
Sbjct: 2415 PQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYS----RPPSR-----PQSRDPFAP 2465
Query: 1400 LLLPVCPLPTGRRDERSGPLASPVLLETGLPLPLPLPLPLPLALPAVLRAQARAPTPLPP 1459
L P P P ++G LA L G P LP A PA A+ P+ PP
Sbjct: 2466 LHKPPRPQPP-EVAFKAGSLAHTSLGAGGFPAALP-------AGPAG-ELHAKVPSGQPP 2516
Query: 1460 -LLPAP----LASCPPPMK----RKPGRPRRSPPSMLSLDGPLVRPPAG--AALGRELLL 1508
+ +P P PM+ + G P PP + P + PP G + G L
Sbjct: 2517 NFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPP----VPQPGLPPPHGINSHFGPGPTL 2572
Query: 1509 LPGQPQTPVFPSTHDPRTVTLDFRNAGIPAPPPP--------LPPQPPPPPPPPPVEPTK 1560
G+PQ+ + T +F +G P P L P PP PPP
Sbjct: 2573 --GKPQSTNY------TVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSVLPPPAPDGS 2624
Query: 1561 LPFKELDNQWPSEAIPPGPRGRDEVTEEYMELAKSRGPWRRPP 1603
LP+ S P + D T LA + P + P
Sbjct: 2625 LPYLSHGASQRSGITSPVEKREDPGTGMGSSLATAELPGTQDP 2667
Score = 60.5 bits (145), Expect = 2e-08
Identities = 105/402 (26%), Positives = 136/402 (33%), Gaps = 100/402 (24%)
Query: 363 SSGPPFKAQPQDSATFAHTPPPAQATPAPGFKSAFSPYQTPVAHFPPPPEEPTATAAFGA 422
+ GP QP++ T P +P P + SP Q +H P EEP +
Sbjct: 792 AEGPHLSPQPEELHLSPQTEEP-HLSPVPE-EPCLSP-QPEESHLSPQSEEPCLSPR--- 845
Query: 423 RDSGEFRRAPAPPPLPPAEPLAKEKPGTPPGP------PPPDTNSME-LGGRPTFGWSPE 475
+ PPL P E+PG P P PPP S+ L G P E
Sbjct: 846 PEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGE 905
Query: 476 PCDSPGTPTLESSPAGPEKPHDSLDSRIEMLLKEQRTKLLFLREPDSDTELQMEGSPISS 535
P SP L SP+G E L Q L PD L SPI +
Sbjct: 906 PPLSPLPEELPLSPSG------------EPSLSPQ------LMPPDP---LPPPLSPIIT 944
Query: 536 SSSQ--LSPLA----PFGTNSQ---------PGFRGPTPPSSRPSSTGLEDISPTPLPDS 580
+++ LSPL PFG P P P + T E + P LP S
Sbjct: 945 AAAPPALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPPS 1004
Query: 581 DEDEELDLGLGPRPP--PEPGPPDPAGLLSQTAEVALDLVGDRTPTSEKMDEGQQSS--- 635
+GP P EP PP + LL + LV +P S+ S
Sbjct: 1005 PGSP-----VGPASPILMEPLPPQCSPLLQHS------LVPQNSPPSQCSPPALPLSVPS 1053
Query: 636 -----GEDMEISDD----EMPSAPITSADCPKPMVVTPGAAAVAAPSVLAPTLPLPPPPG 686
G+ + +SD+ EM + ++ +CP + P A T PLP P G
Sbjct: 1054 PLSPIGKVVGVSDEAELHEMETEKVSEPECP---ALEPSA-----------TSPLPSPMG 1099
Query: 687 FPPLPPPPPPP------------PPQPGFPMPPPLPPPPPPP 716
P P P P P G P P P P
Sbjct: 1100 DLSCPAPSPAPALDDFSGLGEDTAPLDGIDAPGSQPEPGQTP 1141
Score = 60.1 bits (144), Expect = 2e-08
Identities = 122/504 (24%), Positives = 180/504 (35%), Gaps = 133/504 (26%)
Query: 1133 EDEEEVVAREEEEEEEEEEMVAEESMASAGPEDFEQDGEEAALAPGAPAVDSLGMEEEVD 1192
+ +++ + ++++++++ + +S P+ +Q ++ AL PG PA
Sbjct: 3957 QQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQ--QQQQQQVALGPGMPA----------- 4003
Query: 1193 IETEAVAPEERPSMLDEPPLPVGVEE----PADSREPPEEPGLSQEGAMLL--SPEPPAK 1246
+ + P L L G E+ PA S E E P Q G + + +PE A
Sbjct: 4004 ---KPLQHFSSPGALGPTLLLTGKEQNTVDPAVSSEATEGPSTHQGGPLAIGTTPESMAT 4060
Query: 1247 EV-EARPPLSPERAPEHDLEVEPEP-PMMLPLPLQPPLPPPRPPRPPSPPPEPETTDASH 1304
E E +P LS + L V+P+P P L LQPPL
Sbjct: 4061 EPGEVKPSLSGD---SQLLLVQPQPQPQPSSLQLQPPL---------------------- 4095
Query: 1305 PSVPPEPLAEDHPPHTPGLCGSLAKSQSTETVPATPGGEPPLSGGSSGLSLSSPQVPGSP 1364
+P + + HT G G L GSS + S P +
Sbjct: 4096 -RLPGQQQQQVSLLHTAG-----------------GGSHGQLGSGSSSEASSVPHL---- 4133
Query: 1365 FSYPAPSPSLSSGGLPRTPGRDFSFTPTFSEPSGPLLLPVCPLPTGRRDERSGPLASPVL 1424
PS+S G P S T P P+L TG + + GP+
Sbjct: 4134 ----LAQPSVSLGDQPG------SMTQNLLGPQQPMLERPMQNNTGPQPPKPGPV----- 4178
Query: 1425 LETGLPLPLPLPLPLPLALPAVLRAQARAPTPLPPLLPAPLASCPPPMKRKPGRP----R 1480
L++G LP +P L A L+ L L P + ++ + R
Sbjct: 4179 LQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQLQQSQAVR 4238
Query: 1481 RSPPSMLSLDGPLVRPPAGAALGRELLLLPGQPQTPVFPSTHDPRTVTLDFRNAG----- 1535
++PP G P G LL QPQ FP P+T L AG
Sbjct: 4239 QTPP--YQEPGTQTSPLQG--------LLGCQPQLGGFPG---PQTGPLQELGAGPRPQG 4285
Query: 1536 ---IPAPPP---------PLPPQPPPPPPPPPVEPTKLPFKELDNQWPSEA-IPPGPRGR 1582
+PAPP P+ P PPP P P P++LP +Q P+EA +PP G
Sbjct: 4286 PPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLP--SPSSQLPTEAQLPPTHPG- 4342
Query: 1583 DEVTEEYMELAKSRGPWRRPPKKR 1606
K +GP PP R
Sbjct: 4343 ---------TPKPQGPTLEPPPGR 4357
Score = 57.8 bits (138), Expect = 1e-07
Identities = 85/332 (25%), Positives = 110/332 (33%), Gaps = 39/332 (11%)
Query: 1312 LAEDHPPHTPGLCGSLAKSQSTETVPATPGGEPPL-----SGGSSGLSLSSPQVPGSPFS 1366
+AE H P +C + + +T P EP G G ++S Q P P
Sbjct: 361 VAEQHTP----VCSRFSPPEPGDT----PTDEPDALYVACQGQPKGGHVTSMQ-PKEPGP 411
Query: 1367 YPAPSPSLSSGGLPRTPGRDFSFTPTFSEPSGPLLLPVCPLPTGRRDERSGPLASPVLLE 1426
+ L G+ P + PLL P P E S P + P
Sbjct: 412 LQCEAKPLGKAGVQLEPQLEAPLNEEM-----PLLPPPEESPLSPPPEES-PTSPPPEAS 465
Query: 1427 TGLPLPLPLPL-PLPLALPAVLRAQARAPTPLP---PLLPAPLASCPPPMKRKPGRPRRS 1482
P P LP PLP AL + +P P PL P P +S P++ P P
Sbjct: 466 RLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEE 525
Query: 1483 PPSMLSLDGPLVRPPAGAALGRELLLLPGQPQTPVFPSTHDPRTVTLDFRNAGIPAPPPP 1542
P +L+ PL PP + L P P P++ P L P PPP
Sbjct: 526 SPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPP 585
Query: 1543 LPPQPPPPPPPPPVEPTKLPFKELDNQWPSEAIPPGP-----RGRDEVTEEYMELAKSRG 1597
PPP + P PF+E P E P P R + M
Sbjct: 586 EESPMSPPPEASRLFP---PFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEES 642
Query: 1598 PWRRPPKKRH-------EDLVPPAGSPELSPP 1622
P PP+ L PP LSPP
Sbjct: 643 PMSPPPEVSRLSPLPVVSRLSPPPEESPLSPP 674
Score = 55.1 bits (131), Expect = 7e-07
Identities = 89/341 (26%), Positives = 122/341 (35%), Gaps = 67/341 (19%)
Query: 333 SPAVTAVAGATAAFRGSSDLPFGAVGGTGGSS-------GPPFKAQPQDSATFAHTPPPA 385
SP +TA A + G + PFGA G + S P P+ + T PP
Sbjct: 940 SPIITAAAPPALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPM 999
Query: 386 QATPAPGFKSAFSPYQTPVAHFPPPPE-EPTATAAFGARDSGEFRRAPAPPPLPPAEPLA 444
P+PG S P +P+ P PP+ P + ++S P PPA PL+
Sbjct: 1000 ILPPSPG--SPVGP-ASPILMEPLPPQCSPLLQHSLVPQNS------PPSQCSPPALPLS 1050
Query: 445 KEKPGTPPGPPPPDTNSMELGGRPTFGWSPEPCDSPGTPTLESSPAGP------------ 492
P +P G ++ EL T E P P LE S P
Sbjct: 1051 VPSPLSPIGKVVGVSDEAELHEMET-----EKVSEPECPALEPSATSPLPSPMGDLSCPA 1105
Query: 493 EKPHDSLDSRIEMLLKEQRTKLLFLREPDSDTE---------LQMEGSPISSSSSQLSPL 543
P +LD L E L + P S E +++GSP+ +L+P+
Sbjct: 1106 PSPAPALDDFSG--LGEDTAPLDGIDAPGSQPEPGQTPGSLASELKGSPVLLDPEELAPV 1163
Query: 544 APFGT----NSQPGFRGPTPPSSRPSSTGLEDISPTP--LPDSDEDEEL-DLGLG----- 591
P G P P + ++PTP L SD E+ +L G
Sbjct: 1164 TPMEVYPECKQTAGQGSPCEEQEEPRA----PVAPTPPTLIKSDIVNEISNLSQGDASAS 1219
Query: 592 -PRPPPEPGPPDPAGLLSQTAEVALDLVGDRTPTSEKMDEG 631
P P G PDP G S + E +G T S DEG
Sbjct: 1220 FPGSEPLLGSPDPEGGGSLSME-----LGVSTDVSPARDEG 1255
Score = 50.1 bits (118), Expect = 2e-05
Identities = 144/593 (24%), Positives = 191/593 (32%), Gaps = 129/593 (21%)
Query: 250 TPFSQDTAYSSCRLDTPNSYGQGTPLTPRLGTPFSQDSSYSSRQPTP--SYLFSQDPAVT 307
TP Q SC P S P + +P SQ SS S P P + F P
Sbjct: 2384 TPRPQPPPPESCCALPPRSL-PSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTP 2442
Query: 308 -FKARRHESKFTDAYNRRHEHHYVHNSPA-----VTAVAGATA-AFRGSSDLPFGAVGGT 360
F++ S+ R +H P V AG+ A G+ P G
Sbjct: 2443 RFQSPDPYSRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGP 2502
Query: 361 GG-------SSGPPFKAQPQDSATFAHTPPPAQAT--PAPGFKSAFSPYQTPV------- 404
G S PP + + F TP P + T A G S P P
Sbjct: 2503 AGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGLPPPHGI 2562
Query: 405 -AHFPPPPEEPTATAAFGARDSGEFRRAPAPPPLPPAEPLAKEKPGTPP-------GPPP 456
+HF P P + +G F P+ PL P+ E G P PP
Sbjct: 2563 NSHFGPGPTLGKPQSTNYTVATGNFH--PSGSPLGPSSGSTGESYGLSPLRPPSVLPPPA 2620
Query: 457 PDTNSMEL--GGRPTFG-WSP-EPCDSPGTPTLESSPA----GPEKPHDSLDSRIEMLLK 508
PD + L G G SP E + PGT S G + P S S+ E+ +
Sbjct: 2621 PDGSLPYLSHGASQRSGITSPVEKREDPGTGMGSSLATAELPGTQDPGMSGLSQTELEKQ 2680
Query: 509 EQRTKL--LFLREPDSDTELQMEGSPISSSSSQLSPLAPFGTN-SQPGF----RGPTPPS 561
QR +L L +R+ L+ E ++++ + P +G S P F RG TP +
Sbjct: 2681 RQRQRLRELLIRQQIQRNTLRQEKETAAAAAGAVGPPGSWGAEPSSPAFEQLSRGQTPFA 2740
Query: 562 SRPSSTGLEDISPTPL------PDS-DEDEELDLGLGPRPPPEPGP-------------- 600
+ L + P+ L P S D+ L RPPP P
Sbjct: 2741 GTQDKSSLVGLPPSKLSGPILGPGSFPSDDRLS-----RPPPPATPSSMDVNSRQLVGGS 2795
Query: 601 -------PDPAGL----------LSQTAEVALDL---VGDRTPTSEKMDEGQQSSGEDME 640
P P L Q A A + + R P++ + G+Q+ G
Sbjct: 2796 QAFYQRAPYPGSLPLQQQQQQLWQQQQATAATSMRFAMSARFPSTPGPELGRQALGS--- 2852
Query: 641 ISDDEMPSAPITSADCPKPMVVTPGAAAVAAPSVLAPTLPLPPPPGFPPLPPPPPPPPPQ 700
P A I S P P PG A A L + PG P P PP P+
Sbjct: 2853 ------PLAGI-STRLPGPGEPVPGPAGPAQFIELRHNVQKGLGPGGTPFPGQGPPQRPR 2905
Query: 701 ---------------------PGFP-MPPPLPPPPPPPPPAHPAVTVPPPPLP 731
G P P PP P HP P LP
Sbjct: 2906 FYPVSEDPHRLAPEGLRGLAVSGLPPQKPSAPPAPELNNSLHPTPHTKGPTLP 2958
Score = 47.0 bits (110), Expect = 2e-04
Identities = 105/445 (23%), Positives = 147/445 (33%), Gaps = 96/445 (21%)
Query: 334 PAVTAVAGATAAF------RGSSDLPFGAVGGTGGSSGPPFKAQPQDSATFAHTPPPAQA 387
PA+TA A F G S L GA G +GP + +Q ++ P P +
Sbjct: 4567 PAITANFSLFAPFGSGCPVNGQSQLR-GAFGSGALPTGPDYYSQLLTKNNLSNPPTPPSS 4625
Query: 388 ---TPAPGFKSAFSPYQTPVAHFPPPPEEPTATAAFGARDSGEFRRAPAPPPLPPAEPLA 444
TP P + TP P++ A ARDS R +E +
Sbjct: 4626 LPPTPPPSVQQKMVNGVTPSEELGEHPKD-----AASARDSERALR-------DTSEVKS 4673
Query: 445 KEKPGTPPGPPPPDTNSMELGGRPTFGWSPEPCDSPGTPTLESSPAGPEKPHDSLDSRIE 504
+ P PP T + + S E DSP + SSP E
Sbjct: 4674 LDLLAALPTPPHNQTEDVRME-------SDEDSDSPDSIVPASSP--------------E 4712
Query: 505 MLLKEQRTKLLFLREPDSDTELQMEGSPISSSSSQLSPLAPFGTNSQPGFRGPTPPSSRP 564
+L E+ + L + E LSP+ P P P P ++P
Sbjct: 4713 SILGEEAPRFPHLGSGRWEQE-----------DRALSPVIPL----IPRASIPVFPDTKP 4757
Query: 565 -SSTGLEDISPTPLPD------SDEDEELDLGLGPRPPPEPGPPDPAGLLSQTAEVALDL 617
+ GLE P+ S+ L + A LLS + ++
Sbjct: 4758 YGALGLEVPGKLPVTTWEKGKGSEVSVMLTVSAAAAKNLNGVMVAVAELLSMKIPNSYEV 4817
Query: 618 VGDRTP----TSEKMDEGQQSSGEDMEISDDEMPSAPITSADCPKPM-VVTPG---AAAV 669
+ +P T K E + G++ + +P T D K V PG + +
Sbjct: 4818 LFPESPARAGTEPKKGEAEGPGGKEKGLEG----KSPDTGPDWLKQFDAVLPGYTLKSQL 4873
Query: 670 AAPSVLAPTLPLPPPP------------GFPPLPPPPPPPPPQPGFPMPPPLP-PPPPPP 716
S+L P P PP L PPP P PPP P P P
Sbjct: 4874 DILSLLKQESPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPS------PPPSPLAPSPAS 4927
Query: 717 PPAHPAVTVPPPPLPAPPGVPPPPI 741
PP P V +P PL PP P P+
Sbjct: 4928 PPTEPLVELPTEPLAEPPVPSPLPL 4952
Score = 45.8 bits (107), Expect = 4e-04
Identities = 102/428 (23%), Positives = 146/428 (34%), Gaps = 80/428 (18%)
Query: 1284 PPRPPRPPSPPPEPETTDASHPSVPPEPLAEDHPPHTPGLCGS------LAKSQSTETVP 1337
PP PP P P P V P +HP S ++ +S + +
Sbjct: 4619 PPTPPSSLPPTPPPSVQQKMVNGVTPSEELGEHPKDAASARDSERALRDTSEVKSLDLLA 4678
Query: 1338 ATPGGEPPLSGGSSGLSLSSPQVPGSPFSY-PAPSP-SLSSGGLPRTP----GR----DF 1387
A P P + + + S + SP S PA SP S+ PR P GR D
Sbjct: 4679 ALP---TPPHNQTEDVRMESDEDSDSPDSIVPASSPESILGEEAPRFPHLGSGRWEQEDR 4735
Query: 1388 SFTPTF-------------SEPSGPL------LLPVCPLPTGRRDERSGPLA-------- 1420
+ +P ++P G L LPV G+ E S L
Sbjct: 4736 ALSPVIPLIPRASIPVFPDTKPYGALGLEVPGKLPVTTWEKGKGSEVSVMLTVSAAAAKN 4795
Query: 1421 -SPVLLETGLPLPLPLPLPLPLALPAVLRAQARAPTPLPPLLPAPLASCPPPMKRK--PG 1477
+ V++ L + +P + P + ARA T P + P K K G
Sbjct: 4796 LNGVMVAVAELLSMKIPNSYEVLFP---ESPARAGTE-----PKKGEAEGPGGKEKGLEG 4847
Query: 1478 R-PRRSPPSMLSLDGPLVRPPAGAALGRELLLLPGQPQTPVFPSTHDPRTVTLDFRNAGI 1536
+ P P + D L G L +L +L Q P + T + N +
Sbjct: 4848 KSPDTGPDWLKQFDAVL----PGYTLKSQLDILSLLKQESPAPEPPTQHSYTYNVSNLDV 4903
Query: 1537 ---PAPPPPLPPQPPPPPPPPPVEPTKLPFKELDNQWPSEAIPPGPRGRDEVTEEYMELA 1593
APPP P PP P P P P P EL + +E P P + LA
Sbjct: 4904 RQLSAPPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPSP----------LPLA 4953
Query: 1594 KSRGPWRRPPKKRHEDLVPPAGSPELSPPQPLFRPRSEFEEMTILYDIWNGGIDEEDIRF 1653
S R P+ R PP + PP+ ++ + +L I G +ED R
Sbjct: 4954 SSPESARPKPRAR-----PPEEGEDSRPPRLKKWKGVRWKRLRLLLTIQKGSGRQEDERE 5008
Query: 1654 LCVTYERL 1661
+ E+L
Sbjct: 5009 VAEFMEQL 5016
Score = 43.9 bits (102), Expect = 0.002
Identities = 72/303 (23%), Positives = 105/303 (34%), Gaps = 46/303 (15%)
Query: 482 TPTLESSPAGPEKPHDSLDSRIEMLLKEQRTKLLFLREPDSDTELQMEGSPISSSSSQLS 541
TP ++ G KP S DS++ ++ + + + S +LQ Q+S
Sbjct: 4054 TPESMATEPGEVKPSLSGDSQLLLVQPQPQPQ-------PSSLQLQPPLRLPGQQQQQVS 4106
Query: 542 PL--APFGTNSQPGFRGPTPPSSRPSSTGLEDISPTPLPDSDE-----------DEELDL 588
L A G++ Q G + SS P +S P S + +
Sbjct: 4107 LLHTAGGGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSMTQNLLGPQQPMLERPMQN 4166
Query: 589 GLGPRPPPEPGPP-------DPAGLLSQTAEVALDLVG--DRTPTSEKMDEGQQSSGEDM 639
GP+PP +PGP G++ ++ L G + P + QQ + +
Sbjct: 4167 NTGPQPP-KPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQAL 4225
Query: 640 EISDDEMPSAPITSADCPKPMVVTPGAAAVAAPSVLA--PTLPLPPPP--------GFPP 689
+ S + P PG +L P L P P G P
Sbjct: 4226 LMQRQLQQSQAVRQT----PPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGP 4281
Query: 690 LPPPPPPPPPQPG-FPMPPPLPPPPPPPPPAHPAVTVPPPPLPAPPG-VPPPPILPPLPP 747
P PP P PG P L P P PPP+ P P LP+P +P LPP P
Sbjct: 4282 RPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHP 4341
Query: 748 FPP 750
P
Sbjct: 4342 GTP 4344
Score = 41.6 bits (96), Expect = 0.008
Identities = 28/74 (37%), Positives = 29/74 (39%), Gaps = 11/74 (14%)
Query: 677 PTLPLPP------PPGFPPLPPPPPPPPPQPGFPMPPPLP----PPPPPPPPAHPAVTVP 726
P LP PP P P P PPP P +P P P P P PP HP P
Sbjct: 4287 PRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGTPKP 4346
Query: 727 P-PPLPAPPGVPPP 739
P L PPG P
Sbjct: 4347 QGPTLEPPPGRVSP 4360
Score = 40.8 bits (94), Expect = 0.013
Identities = 49/178 (27%), Positives = 59/178 (33%), Gaps = 37/178 (20%)
Query: 679 LPLPPPPGFPPLPPPPPPPPPQPGFPMPPPLPPPPPPPPPAHPAVTVPPPPLPAPPGVPP 738
L +PP PG PPP P G P P PA +VP P P +
Sbjct: 2104 LRIPPQPGALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDSPGELFLKL 2163
Query: 739 PPILPPLPPF--PPGLFPVMQVDMSHVLGGQWGGMPMSFQMQTQVLSRLMTGQGACPYPP 796
PP +P P P GL P ++ R T YPP
Sbjct: 2164 PPQVPAQVPSQDPFGLAPAYPLE-----------------------PRFPTAPPT--YPP 2198
Query: 797 FMAAAAAAASAGLQFVNLPPYRGPFSLSNSG-PGRGQHWPP-LPKFDPSVPPPGYMPR 852
+ + A A PP G S +G PG PP P+ PS P P PR
Sbjct: 2199 YPSPTGAPAQ--------PPMLGASSRPGAGQPGEFHTTPPGTPRHQPSTPDPFLKPR 2248
Score = 40.0 bits (92), Expect = 0.022
Identities = 86/327 (26%), Positives = 112/327 (34%), Gaps = 81/327 (24%)
Query: 1331 QSTETVPATPGGE-PPLSGGSSGLSLSSPQVPGSPFSYPAPSPSLSSGGLPRTPGRDFSF 1389
Q ET A G PP S G+ S + Q+ + S GLP
Sbjct: 2702 QEKETAAAAAGAVGPPGSWGAEPSSPAFEQLSRGQTPFAGTQDKSSLVGLPP-------- 2753
Query: 1390 TPTFSEPSGPLLLPVCPLPTGRRDERSGPLASPVLLETGLP------------LPLPLPL 1437
S+ SGP+L P P+ R R P A+P ++ P P L
Sbjct: 2754 ----SKLSGPILGPGS-FPSDDRLSRPPPPATPSSMDVNSRQLVGGSQAFYQRAPYPGSL 2808
Query: 1438 PLPLALPAVLRAQ-ARAPTPLPPLLPAPLASCPPPM--KRKPGRPRRSPPSMLSLDGPLV 1494
PL + + Q A A T + + A S P P ++ G P + L G V
Sbjct: 2809 PLQQQQQQLWQQQQATAATSMRFAMSARFPSTPGPELGRQALGSPLAGISTRLPGPGEPV 2868
Query: 1495 RPPAGAA------------LGRELLLLPGQ--PQTPVF-PSTHDPRTVTLD-FRNAGIPA 1538
PAG A LG PGQ PQ P F P + DP + + R +
Sbjct: 2869 PGPAGPAQFIELRHNVQKGLGPGGTPFPGQGPPQRPRFYPVSEDPHRLAPEGLRGLAVSG 2928
Query: 1539 PPPPLPPQPPPPPPPPPVEPTKLPFKELDNQWPSEAIPPGPRGRDEVTEEYMELAKSRGP 1598
LPPQ P PP P EL+N ++ P P + +EL
Sbjct: 2929 ----LPPQKPSAPPAP----------ELNN-----SLHPTPHTKGPTLPTGLELV----- 2964
Query: 1599 WRRPPKKRHEDLVPPAGSPELSPPQPL 1625
RPP S EL P PL
Sbjct: 2965 -NRPP-----------SSTELGRPNPL 2979
Score = 39.7 bits (91), Expect = 0.029
Identities = 65/271 (23%), Positives = 96/271 (35%), Gaps = 32/271 (11%)
Query: 1285 PRPPRPPS-PPPEPETTDASHPSVPPE--PLAEDHPPHTPGLCGSLAKSQSTETVPATPG 1341
P P P PPP + ++ SV PE P E+ H P C + E PA
Sbjct: 3091 PGPLGPEERPPPAADASEPRLASVLPEVKPKVEEGGRH-PSPCQFTIATPKVEPAPAANS 3149
Query: 1342 GEPPLSGGSSGLSLSSPQVPGSPFSYPAPSPSLSSGGLPRTPGRDFSFTPTFSEPSGPLL 1401
L G S + ++ PFS + +S G P S P G L
Sbjct: 3150 LGLGLKPGQSMMGSRDTRMGTGPFSSSGHTAEKASFGATGGPPAHLLTPSPLSGPGGSSL 3209
Query: 1402 LPVCPLPTGRRDERSGPLASPVLL---ETGLPLPLPLPLPLPLALPAVLRAQARAPTPLP 1458
L L +G GP AS L E+ L + LPL + +L + +
Sbjct: 3210 LEKFELESGALTLPGGPAASGDELDKMESSL-----VASELPLLIEDLLEHEKKELQKKQ 3264
Query: 1459 PLLPAPLASCPPPMKRKPGRPRRSPPSMLSLDGPLVRPPAGAALGRELLLLPGQPQTPVF 1518
L A P ++ + ++ S+LS GP + + LP + +P
Sbjct: 3265 QL----SAQLQPAQQQ---QQQQQQHSLLSAPGP-----------AQAMSLPHEGSSPSL 3306
Query: 1519 PSTHDPRTVTLDFRNAGIPAPPPPLPPQPPP 1549
+ + ++L A P P PL P PP
Sbjct: 3307 AGSQ--QQLSLGLAGARQPGLPQPLMPTQPP 3335
Score = 39.3 bits (90), Expect = 0.037
Identities = 63/261 (24%), Positives = 89/261 (34%), Gaps = 57/261 (21%)
Query: 478 DSPGTPTLESSPAGPEKPHDSLDSRIEMLLKEQRTKLLFLREPDSDTELQMEGSPISSSS 537
D+ L P +K D L S + L KE + EL + + +
Sbjct: 4511 DAAARKPLTPKPKRVQKASDRLVSSRKKLRKEDGVRASEALLKQLKQELSLLPLTEPAIT 4570
Query: 538 SQLSPLAPFGT----NSQPGFRG--------------------------PTPPSSRPSST 567
+ S APFG+ N Q RG PTPPSS P
Sbjct: 4571 ANFSLFAPFGSGCPVNGQSQLRGAFGSGALPTGPDYYSQLLTKNNLSNPPTPPSSLP--- 4627
Query: 568 GLEDISPTPLPDSDE--------DEELDLGLGPRPPPEPGPPDPAGLLSQTAEV-ALDLV 618
PTP P + EEL G P D L T+EV +LDL+
Sbjct: 4628 ------PTPPPSVQQKMVNGVTPSEEL----GEHPKDAASARDSERALRDTSEVKSLDLL 4677
Query: 619 GDR-TPTSEKMDEGQQSSGEDMEISDDEMPSAP---ITSADCPKPMVVTPGAAAVAAPSV 674
TP + ++ + S ED + D +P++ I + P+ + G
Sbjct: 4678 AALPTPPHNQTEDVRMESDEDSDSPDSIVPASSPESILGEEAPRFPHLGSGRWE-QEDRA 4736
Query: 675 LAPTLPLPPPPGFPPLPPPPP 695
L+P +PL P P P P
Sbjct: 4737 LSPVIPLIPRASIPVFPDTKP 4757
Score = 38.9 bits (89), Expect = 0.049
Identities = 25/68 (36%), Positives = 26/68 (38%), Gaps = 6/68 (8%)
Query: 681 LPPPPGF----PPLPPPPPPPPPQPGFPMPPPLPPPPPPPPPAHPAVTVPPPPLPAPPGV 736
LP PPG P L P P PPP P P P P P P PP P P
Sbjct: 4289 LPAPPGALSTGPVLGPVHPTPPPS--SPQEPKRPSQLPSPSSQLPTEAQLPPTHPGTPKP 4346
Query: 737 PPPPILPP 744
P + PP
Sbjct: 4347 QGPTLEPP 4354
Score = 38.9 bits (89), Expect = 0.049
Identities = 43/170 (25%), Positives = 61/170 (35%), Gaps = 25/170 (14%)
Query: 1200 PEERPSMLDEPPLPVGVEEPADSREPPEEPGLSQEGAMLLSPEPPAKEVEARPPLSPERA 1259
P + E P G E + E PG ++G SP+ ++ + P
Sbjct: 4812 PNSYEVLFPESPARAGTEP---KKGEAEGPGGKEKGLEGKSPDTGPDWLKQFDAVLPGYT 4868
Query: 1260 PEHDLEV---------EPEPPM-------MLPLPLQPPLPPPRPPRPPSPPPEPETTDAS 1303
+ L++ PEPP + L ++ PP P PSPPP P +
Sbjct: 4869 LKSQLDILSLLKQESPAPEPPTQHSYTYNVSNLDVRQLSAPP--PEEPSPPPSPLAPSPA 4926
Query: 1304 HPSVPPEPLAE--DHPPHTPGLCGSLAKSQSTETVPATPGGEPPLSGGSS 1351
P P EPL E P P + L + S E+ P PP G S
Sbjct: 4927 SP--PTEPLVELPTEPLAEPPVPSPLPLASSPESARPKPRARPPEEGEDS 4974
Score = 36.2 bits (82), Expect = 0.32
Identities = 79/351 (22%), Positives = 111/351 (31%), Gaps = 70/351 (19%)
Query: 388 TPAPGFKSAFSPYQTPVAHFPPPPEEPTATAAFGARDSGEFRRAPAPPPLPPAEPLAKEK 447
TP PG P Q P F P E+P A G R P P PPA L
Sbjct: 2893 TPFPGQ----GPPQRP--RFYPVSEDPHRLAPEGLRGLAVSGLPPQKPSAPPAPELNNSL 2946
Query: 448 PGTPPGPPPPDTNSMELGGRPTFGWSPEPCDSPGTPTLESSPAGPEKP--------HDSL 499
TP P +EL RP S P LE+ E P H +L
Sbjct: 2947 HPTPHTKGPTLPTGLELVNRPP---SSTELGRPNPLALEAGKLPCEDPELDDDFDAHKAL 3003
Query: 500 -------------------------------DSRIEMLLKEQRTKLLFLREPDSDT---- 524
D ++ LL LL +P+ DT
Sbjct: 3004 EDDEELAHLGLGVDVAKGDDELGTLENLETNDPHLDDLLNGDEFDLLAYTDPELDTGDKK 3063
Query: 525 ELQMEGSPISSSSSQLSPLAPFGTNSQPGFRGP---TPPSSRPSSTGLEDISPTPLPDSD 581
++ E + S+++ + +PG GP PP++ S L + P P +
Sbjct: 3064 DIFNEHLRLVESANEKAEREALLRGVEPGPLGPEERPPPAADASEPRLASVLPEVKPKVE 3123
Query: 582 EDEELDLGLGPRP------PPEPGPPDPAGLLSQTAEVALDLVGDRTPTSEKMDEGQ-QS 634
E G P P P+ P A L + ++G R +M G S
Sbjct: 3124 EG-----GRHPSPCQFTIATPKVEPAPAANSLGLGLKPGQSMMGSR---DTRMGTGPFSS 3175
Query: 635 SGEDMEISDDEMPSAPITSADCPKPMVVTPGAAAVAAPSVLAPTLPLPPPP 685
SG E + P P P+ G++ + + + L LP P
Sbjct: 3176 SGHTAEKASFGATGGPPAHLLTPSPLSGPGGSSLLEKFELESGALTLPGGP 3226
Score = 35.8 bits (81), Expect = 0.41
Identities = 82/368 (22%), Positives = 130/368 (35%), Gaps = 44/368 (11%)
Query: 969 PPDTTSSGDQKRLRPSTSVDE-----EDEESERERDRDMADTPCELAKRDPKGVGVRRRP 1023
PP S QK + T +E +D S R+ +R + DT E+ D + P
Sbjct: 4627 PPTPPPSVQQKMVNGVTPSEELGEHPKDAASARDSERALRDTS-EVKSLDL----LAALP 4681
Query: 1024 ARPLELDSGGEEDEKESLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDESENDDEDTAL 1083
P ED + E+ +S + A E ++ + ED AL
Sbjct: 4682 TPP----HNQTEDVRMESDEDSDSPDSIVPASSPESILGEEAPRFPHLGSGRWEQEDRAL 4737
Query: 1084 S-------EASEKDEGDSDEEETVSIVTSKAEATSSSESSESSEFESSSESSPSSSEDEE 1136
S AS D+ + + ++ E + SE S +++++
Sbjct: 4738 SPVIPLIPRASIPVFPDTKPYGALGLEVPGKLPVTTWEKGKGSEVSVMLTVSAAAAKNLN 4797
Query: 1137 EVVAREEE----EEEEEEEMVAEESMASAGPEDFEQDGEEAALAPGAPAVDSLGMEEEVD 1192
V+ E + E++ ES A AG E + + E PG G +
Sbjct: 4798 GVMVAVAELLSMKIPNSYEVLFPESPARAGTEPKKGEAE----GPGGKEKGLEGKSPDTG 4853
Query: 1193 IET----EAVAPEER-PSMLDEPPLPVGVEEPADSREPPEEPGLSQEGAML----LSPEP 1243
+ +AV P S LD L +++ + + EPP + + + L LS P
Sbjct: 4854 PDWLKQFDAVLPGYTLKSQLDILSL---LKQESPAPEPPTQHSYTYNVSNLDVRQLSAPP 4910
Query: 1244 PAKEVEARPPLSPERA--PEHDLEVEPEPPMMLPLPLQPPLPPPRPPRPPSPPPEPETTD 1301
P + PL+P A P L P P+ P P+ PLP P P P +
Sbjct: 4911 PEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEP-PVPSPLPLASSPESARPKPRARPPE 4969
Query: 1302 ASHPSVPP 1309
S PP
Sbjct: 4970 EGEDSRPP 4977
Score = 35.0 bits (79), Expect = 0.71
Identities = 30/103 (29%), Positives = 39/103 (37%), Gaps = 8/103 (7%)
Query: 409 PPPEEPTATAAFGARDSGEFRRAPAPPP---LPPAEPLAKEKPGTPPGPPPPDTNSMELG 465
P PE PT + + + R+ APPP PP PLA P +PP P + + L
Sbjct: 4884 PAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLA-PSPASPPTEPLVELPTEPLA 4942
Query: 466 GRPTFGWSPEPCDSPGTPTLESSPAGPEKPHDSLDSRIEMLLK 508
P P P +P P + DSR L K
Sbjct: 4943 EPPV----PSPLPLASSPESARPKPRARPPEEGEDSRPPRLKK 4981
Score = 34.7 bits (78), Expect = 0.92
Identities = 38/137 (27%), Positives = 46/137 (33%), Gaps = 29/137 (21%)
Query: 371 QPQDSATFAHTPP----PAQATPAPGFKSAFSPYQTPVAHFPPPPEEPTATAAFGARDSG 426
Q Q S TPP Q +P G Q + FP P P G R G
Sbjct: 4230 QLQQSQAVRQTPPYQEPGTQTSPLQGLLGC----QPQLGGFPGPQTGPLQELGAGPRPQG 4285
Query: 427 EFRRAPAPPPL--------------PPAEPLAKEKPGTPPGPPPPDTNSMELGGRPTFGW 472
R PAPP PP+ P ++P P P +L PT
Sbjct: 4286 P-PRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQL--PPTHPG 4342
Query: 473 SPEPCDSPGTPTLESSP 489
+P+ P PTLE P
Sbjct: 4343 TPK----PQGPTLEPPP 4355
Score = 34.3 bits (77), Expect = 1.2
Identities = 99/424 (23%), Positives = 137/424 (32%), Gaps = 103/424 (24%)
Query: 1204 PSMLDEPP--LPVG-VEEPADSREPPEEPGLSQEGAMLLSPEPPAKEVEARPPLSPERAP 1260
P L PP L G V P PP P + + L SP ++ P + P
Sbjct: 4286 PPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSP-------SSQLPTEAQLPP 4338
Query: 1261 EHDLEVEPEPPMMLPLPLQPPLPPPRPPRPPSPPPEPETTDASHPSVPPEPLAEDHPP-- 1318
H +P+ P + P PP R + + + P PP+ LAE P
Sbjct: 4339 THPGTPKPQGPTLEP-------PPGRVSPAAAQLADTLFSKGLGPWDPPDNLAETQKPEQ 4391
Query: 1319 ------HTPGLCGSLAKSQSTETVPATPGGEPPLSGGSSGLSLSSPQVPGSPFSYPAPSP 1372
H + G + S ++ P EP G S + G P P S
Sbjct: 4392 SSLVPGHLDQVNGQVVPEASQLSIKQEPREEPCALGAQS----VKREANGEPIGAPGTSN 4447
Query: 1373 SLSSGGLPRTPGRDFSFTPTFSEPSGPLLLPV------CPLPTGR-----RDERSGPLAS 1421
L G PR+ +G LLL L TGR R E +G + S
Sbjct: 4448 HLLLAG-PRS-------------EAGHLLLQKLLRAKNVQLSTGRGSEGLRAEINGHIDS 4493
Query: 1422 PVLLETGLPLPLPLPLPLPLALPAVLRAQARAPTPLPPLLPAPLASCPPPMKRKPGRPRR 1481
+ GL L P+ + A A PL P P +++ R
Sbjct: 4494 KL---AGLEQKLQ-------GTPS-NKEDAAARKPLTPK--------PKRVQKASDRLVS 4534
Query: 1482 SPPSMLSLDGPLVRPPAGAALGRELLLLP-GQPQTPVFPSTHDP----------RTVTLD 1530
S + DG L +EL LLP +P S P +
Sbjct: 4535 SRKKLRKEDGVRASEALLKQLKQELSLLPLTEPAITANFSLFAPFGSGCPVNGQSQLRGA 4594
Query: 1531 FRNAGIPAPP--------------PPLPPQPPPPPPPPPVEPTKLPFKELDNQWPSEAIP 1576
F + +P P PP PP PP PPP V+ K ++ PSE +
Sbjct: 4595 FGSGALPTGPDYYSQLLTKNNLSNPPTPPSSLPPTPPPSVQQ-----KMVNGVTPSEELG 4649
Query: 1577 PGPR 1580
P+
Sbjct: 4650 EHPK 4653
Score = 33.5 bits (75), Expect = 2.1
Identities = 22/71 (30%), Positives = 29/71 (40%), Gaps = 16/71 (22%)
Query: 1252 PPLSPERAPEHDLEVEPEPPMMLPLPLQPPLPPPRPPRPPSPPPEPETTDASHPSVPPEP 1311
PP P P V +P + P L+ PP+ PS PP PE ++ HP+
Sbjct: 2900 PPQRPRFYP-----VSEDPHRLAPEGLRGLAVSGLPPQKPSAPPAPELNNSLHPT----- 2949
Query: 1312 LAEDHPPHTPG 1322
PHT G
Sbjct: 2950 ------PHTKG 2954
Score = 33.5 bits (75), Expect = 2.1
Identities = 41/156 (26%), Positives = 49/156 (31%), Gaps = 40/156 (25%)
Query: 346 FRGSSDLPFGAVGGTGGSSGPPFKAQPQDSATFAHTPPPAQATPAPGFKSAFSPYQTPVA 405
F G P +G GPP PAP + P PV
Sbjct: 4266 FPGPQTGPLQELGAGPRPQGPP-------------------RLPAPPGALSTGPVLGPVH 4306
Query: 406 HFPPP--PEEPTATAAFGARDSGEFRRAPAPPPLPPAEPLAKEKPGTPPGPPPPDTNSME 463
PPP P+EP + + S + P LPP P KP P PPP S
Sbjct: 4307 PTPPPSSPQEPKRPSQLPSPSS----QLPTEAQLPPTHP-GTPKPQGPTLEPPPGRVS-- 4359
Query: 464 LGGRPTFGWSPEPCDSPGTPTLESSPAGPEKPHDSL 499
P + TL S GP P D+L
Sbjct: 4360 ------------PAAAQLADTLFSKGLGPWDPPDNL 4383
Score = 33.1 bits (74), Expect = 2.7
Identities = 24/60 (40%), Positives = 27/60 (45%), Gaps = 9/60 (15%)
Query: 698 PPQPGFPMPP--PLPPPPPPPPPAHPAVTVPPPPLPAPPG-VPPPPILPPLPPFPPGLFP 754
P GFP P PL P P P P LPAPPG + P+L P+ P PP P
Sbjct: 4261 PQLGGFPGPQTGPLQELGAGPRPQGP------PRLPAPPGALSTGPVLGPVHPTPPPSSP 4314
Score = 32.7 bits (73), Expect = 3.5
Identities = 20/51 (39%), Positives = 21/51 (41%), Gaps = 6/51 (11%)
Query: 677 PTLPLPPPPGFPPLPP---PPPPPPPQPGFPMPPPLPPPPP---PPPPAHP 721
P PL P P PP P P P +P P P PL P P P A P
Sbjct: 4917 PPSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPKPRARP 4967
Score = 31.6 bits (70), Expect = 7.8
Identities = 38/129 (29%), Positives = 56/129 (43%), Gaps = 14/129 (10%)
Query: 1244 PAKEVEARP-PLSPERAPEHDLEVEPEPPMMLPLPLQPPLPPPRPPRPPSPPPEPET--- 1299
P +E+ A P P P R P + P ++ P+ PP P+ P+ PS P P +
Sbjct: 4273 PLQELGAGPRPQGPPRLPAPPGALSTGP-VLGPVHPTPPPSSPQEPKRPSQLPSPSSQLP 4331
Query: 1300 TDA----SHPSVPPEPLAEDHPPHTPGLCGSLAKSQSTETVPATPGG--EPPLSGGSSGL 1353
T+A +HP P PP PG S A +Q +T+ + G +PP + +
Sbjct: 4332 TEAQLPPTHPGTPKPQGPTLEPP--PGRV-SPAAAQLADTLFSKGLGPWDPPDNLAETQK 4388
Query: 1354 SLSSPQVPG 1362
S VPG
Sbjct: 4389 PEQSSLVPG 4397
>gi|160707881 formin 2 [Homo sapiens]
Length = 1722
Score = 115 bits (287), Expect = 5e-25
Identities = 154/529 (29%), Positives = 188/529 (35%), Gaps = 135/529 (25%)
Query: 379 AHTPPPAQATPAPGFKSAFSPYQTPVAHFPPPPEEPTATAAFGARDSGEFRRA---PAPP 435
+H P + + P P +S Q PP + S F+ + P+PP
Sbjct: 800 SHQPTQSISQPPPPPSLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPP 859
Query: 436 PLPPAEPLAKEKPGTPPGPPPPDTNSMELGGRPTFGWSPEPCDSPGTPTLESSPAGPEKP 495
PLP E + PG PPPP P PTL S+ A P+ P
Sbjct: 860 PLPCTES-SSSMPGLGMVPPPPP-----------------PLPGMTVPTLPST-AIPQPP 900
Query: 496 HDSLDSRIEMLLKEQRTKLLFLREPDSDTELQMEGSPISSS--SSQLSPLAPFGTNSQPG 553
Q T++L P L G P + + PL P PG
Sbjct: 901 ------------PLQGTEML----PPPPPPLPGAGIPPPPPLPGAGILPLPPL-----PG 939
Query: 554 FRGPTPPSSRPSSTGLEDISPTPLPDSDEDEELDLGLG-PRPPPEPGP--PDPAGLLSQT 610
P PP G P PLP G G P PPP PG P P L
Sbjct: 940 AGIPPPPPL----PGAAIPPPPPLP----------GAGIPLPPPLPGAGIPPPPPLPGAG 985
Query: 611 AEVALDLVGDRTPTSEKMDEGQQSSGEDMEISDDEMPSAPITSADCPKPMVVTPGAAAVA 670
L G P + G + P P+ A P P + PGA
Sbjct: 986 IPPPPPLPGAGIPPPPPLP------GAGIP------PPPPLPGAGIPPPPPL-PGAGIPP 1032
Query: 671 APSVLAPTLPLPPP---PGFPPLPP------PPPPPPPQPGFPMPPPLP-----PPPP-- 714
P + +P PPP G PP PP PPPPP P G P PPPLP PPPP
Sbjct: 1033 PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP 1092
Query: 715 ----PPPPAHPAVTVPPPP------LPAPP-----GVPPPPILPP--LPPFPPGLFPVMQ 757
PPPP P V +PPPP +P PP G+PPPP LP +PP PP P +
Sbjct: 1093 GAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP--LPRVG 1150
Query: 758 VDMSHVLGGQWGGMPMSFQMQTQVLSRLMTGQGACPYPPFMAAAAAAASAGLQFVNLPPY 817
+ L G G+P + G G P PP + L V +PP
Sbjct: 1151 IPPPPPLPG--AGIPPPPPLP---------GAGIPPPPP-LPGVGIPPPPPLPGVGIPP- 1197
Query: 818 RGPFSLSNSG-------PGRG---QHWPPLPKFDPSVPPPGYMPRQEDP 856
P L +G PG G PPLP +PPP +P P
Sbjct: 1198 --PPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPGTGIPPPPLLPVSGPP 1244
Score = 110 bits (274), Expect = 2e-23
Identities = 124/439 (28%), Positives = 161/439 (36%), Gaps = 97/439 (22%)
Query: 481 GTPTLESSPAGPEK-PHDSLDSRIEMLLKEQRTKLLFLREPDSDTELQMEGSPISSSSSQ 539
G P P G E P S I +++ +R + Q++ + S SQ
Sbjct: 762 GLPGRPPCPPGAESGPQTKFCSEISLIVSPRRISV------------QLDSHQPTQSISQ 809
Query: 540 LSPLAPFGTNSQPGFRGPTPPSSRPS----------STGLEDI----SPTPLPDSDEDEE 585
P ++ G G PP S + S+ ++ SP PLP ++
Sbjct: 810 PPPPPSLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTESSSS 869
Query: 586 LDLGLGPRPPPEPGPPDPAGLLSQTAEVALDLVGDRTPTSEKMDEGQQSSGEDMEISDDE 645
+ GLG PPP P P G PT Q + E+
Sbjct: 870 MP-GLGMVPPPPPPLP-----------------GMTVPTLPSTAIPQPPPLQGTEMLPPP 911
Query: 646 MPSAPITSADCPKPMVVTPGAAAVAAPSVLAPTLPLPPPPGFPPLPPPPPPPPPQPGFPM 705
P P P P+ PGA + P + P +PPPP P PPPPP P G P+
Sbjct: 912 PPPLPGAGIPPPPPL---PGAGILPLPPL--PGAGIPPPPPLPGAAIPPPPPLPGAGIPL 966
Query: 706 PPPLP----PPPP-------PPPPAHPAVTVPPPP------LPAPP-----GVPPPPIL- 742
PPPLP PPPP PPPP P +PPPP +P PP G+PPPP L
Sbjct: 967 PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP 1026
Query: 743 ----PPLPPF------PPGLFPVMQVDMSHVLGGQWGGMPMSFQMQTQVLSRLMTGQGA- 791
PP PP PP P + L G G+P + + GA
Sbjct: 1027 GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG--AGIPPPPPLPGAGIPPPPPLPGAG 1084
Query: 792 CPYPPFMAAAAAAASAGLQFVNLPPYRGPFSLSNSG-------PGRGQHWPPLPKFDPSV 844
P PP + A L V +PP P L +G PG G PP P +
Sbjct: 1085 IPPPPPLPGAGIPPPPPLPGVGIPP---PPPLPGAGIPPPPPLPGAGIP-PPPPLPGAGI 1140
Query: 845 PPPGYMPRQEDPHKATVDG 863
PPP +PR P + G
Sbjct: 1141 PPPPPLPRVGIPPPPPLPG 1159
Score = 109 bits (272), Expect = 3e-23
Identities = 156/577 (27%), Positives = 187/577 (32%), Gaps = 133/577 (23%)
Query: 288 SYSSRQPTPSYLFSQDPAVTFKARRHESKFTDAYNRRHEHHYVHNSPAVTAVAGATAAFR 347
S S P PS L+S H + + HEH ++AF+
Sbjct: 806 SISQPPPPPSLLWSAGQGQPGSQPPHS--ISTEFQTSHEH-------------SVSSAFK 850
Query: 348 GSSDLPFGAVGGTGGSSGPPFKAQPQDSAT--FAHTPPPAQATPAPGFKSAFSPYQTPVA 405
S ++P S PP S+ PPP P PG P A
Sbjct: 851 NSCNIP----------SPPPLPCTESSSSMPGLGMVPPPPP--PLPGMTVPTLP---STA 895
Query: 406 HFPPPPEEPTATAAFGARDSGEFRRAPAPPPLPPAEPLAKEKPGTPPGPPPPDTNSMELG 465
PPP + T P PPPLP A G PP PP P + L
Sbjct: 896 IPQPPPLQGTEMLP------------PPPPPLPGA--------GIPPPPPLPGAGILPLP 935
Query: 466 GRPTFGWSPEPCDSPGTPTLESSPAGPEKPHDSLDSRIEMLLKEQRTKLLFLREPDSDTE 525
P G P P PG + P P P + L P
Sbjct: 936 PLPGAGIPPPP-PLPGA----AIPPPPPLPGAGIP----------------LPPPLPGAG 974
Query: 526 LQMEGSPISSSSSQLSPLAPFGTNSQPGFRGPTPPSSRPSSTGLEDISPTPLPDSDEDEE 585
+ + PL G P G P P G P PLP +
Sbjct: 975 IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPP-PPLPGAGIPPPPPLPGAGIPPP 1033
Query: 586 LDL-GLG-PRPPPEPGP--PDPAGLLSQTAEVALDLVGDRTPTSEKMDEGQQSSGEDMEI 641
L G G P PPP PG P P L L G P
Sbjct: 1034 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIP------------------ 1075
Query: 642 SDDEMPSAPITSADCPKPMVVTPGAAAVAAPSVLAPTLPLPPPPGFPPLPPPPPPPPPQP 701
P P+ A P P + PGA P + P + +PPPP P PPPPP P
Sbjct: 1076 -----PPPPLPGAGIPPPPPL-PGAGIPPPPPL--PGVGIPPPPPLPGAGIPPPPPLPGA 1127
Query: 702 GFPMPPPLP----PPPP-------PPPPAHPAVTVPPPPLPAPPGVPPPPILPPLPPFPP 750
G P PPPLP PPPP PPPP P +PPPP G+PPPP LP + PP
Sbjct: 1128 GIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPP 1187
Query: 751 GLFPVMQVDMSHVLGGQWGGMPMSFQMQTQVLSRLMTGQGACPYPPFMAAAAAAASAGLQ 810
P + + L G G+P + G G PP A G+
Sbjct: 1188 PPLPGVGIPPPPPLPG--AGIPP---------PPPLPGMG---IPPAPAPPLPPPGTGIP 1233
Query: 811 FVNLPPYRGPFSLSNSGPGRGQHWPPLPKFDPSVPPP 847
L P GP L P G P P+ +PPP
Sbjct: 1234 PPPLLPVSGPPLL----PQVGSSTLPTPQVCGFLPPP 1266
Score = 108 bits (270), Expect = 5e-23
Identities = 140/471 (29%), Positives = 168/471 (35%), Gaps = 92/471 (19%)
Query: 1177 PGAPAVDSLGMEEEVDIETEAVAPEERPSMLDEPPLPVGVEEPADSREPPEEPGLSQEGA 1236
PG+ S+ E + E + + + PP P+ E + S PGL
Sbjct: 825 PGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPP-PLPCTESSSSM-----PGLG---- 874
Query: 1237 MLLSPEPPAKEVEARPPLSPERAPEHDLEVEPEPPMMLPLPLQPPLPPPRPPR--PPSPP 1294
+ P PP PPL P P+PP + + PP PPP P PP PP
Sbjct: 875 --MVPPPP-------PPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPP 925
Query: 1295 -------PEPETTDASHPSVPPEPLAEDHPPHTPGLCGSLAKSQSTETVPATPGG----E 1343
P P A P PP P A PP P L G+ P PG
Sbjct: 926 LPGAGILPLPPLPGAGIPPPPPLPGAAIPPP--PPLPGA-----GIPLPPPLPGAGIPPP 978
Query: 1344 PPLSGGSSGLSLSSPQVPGSPFSYPAPSPSLSSGGLPRTPGRDFSFTPTFSEPSGPLLLP 1403
PPL G P P P + P P L G+P P + P G + P
Sbjct: 979 PPLPGA------GIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP 1032
Query: 1404 VCPLPTGRRDERSGPLASPVLLETGLPLPLPLP---LPLPLALPAVLRAQARAPTPLPPL 1460
PLP +G P L G+P P PLP +P P LP A P PP
Sbjct: 1033 PPPLP------GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG-------AGIPPPPP 1079
Query: 1461 LPAPLASCPPPMKRKPGRPRRSPPSMLSLDGPLVRPPAGAALGRELLLLPGQPQTPVFPS 1520
LP PPP+ PG PP + + P P GA G P P P
Sbjct: 1080 LPGAGIPPPPPL---PGAGIPPPPPLPGVGIPPPPPLPGA----------GIPPPPPLPG 1126
Query: 1521 THDPRTVTLDFRNAGIPAPPPPLPP---QPPPP------PPPPPVEPTKLPFKELDNQWP 1571
P L AGIP PPPPLP PPPP PPPPP+ +P P
Sbjct: 1127 AGIPPPPPLP--GAGIP-PPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIP---PPPPLP 1180
Query: 1572 SEAIPPGPRGRDEVTEEYMELAKSRGPWRRPPKKRHEDLVPPAGSPELSPP 1622
IPP P L + P PP +PPA +P L PP
Sbjct: 1181 GVGIPPPPPLPGVGIPPPPPLPGAGIP---PPPPLPGMGIPPAPAPPLPPP 1228
Score = 100 bits (249), Expect = 1e-20
Identities = 127/397 (31%), Positives = 144/397 (36%), Gaps = 88/397 (22%)
Query: 1200 PEERPSMLDEPPLPVGVEEPADSREPPEEPGLSQEGAMLLSPEPPAKEVEARPPLSPERA 1259
P + ML PP P+ P PP P L G + L P P A + PPL
Sbjct: 901 PLQGTEMLPPPPPPL----PGAGIPPP--PPLPGAGILPLPPLPGAG-IPPPPPLPGAAI 953
Query: 1260 PEHDLEVEPEPPMMLP---LPLQPPLP----PPRPPRPPSP-PPEPETTDASHPSVPPEP 1311
P PP LP +PL PPLP PP PP P + PP P A P PP P
Sbjct: 954 P---------PPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP 1004
Query: 1312 LAEDHPPHTPGLCGSLAKSQSTETVPATPGG----EPPLSGGSSGLSLSSPQVPGSPFSY 1367
A PP P L G+ P PG PPL G P P P +
Sbjct: 1005 GAGIPPP--PPLPGA-----GIPPPPPLPGAGIPPPPPLPGAGI------PPPPPLPGAG 1051
Query: 1368 PAPSPSLSSGGLPRTPGRDFSFTPTFSEPSGPLLLPVCPLPTGRRDERSGPLASPVLLET 1427
P P L G+P P + P G + P PLP +G P L
Sbjct: 1052 IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG------AGIPPPPPLPGV 1105
Query: 1428 GLPLPLPLP---LPLPLALPAVLRAQARAPTPLPPLLPAPLASCPPPMKR-----KPGRP 1479
G+P P PLP +P P LP A P PP LP PPP+ R P P
Sbjct: 1106 GIPPPPPLPGAGIPPPPPLPG-------AGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLP 1158
Query: 1480 RRSPPSMLSLDGPLVRPPAGAALGRELLLLPGQ--PQTPVFPSTHDPRTVTLDFRNAGIP 1537
P L G + PP LPG P P P P L AGIP
Sbjct: 1159 GAGIPPPPPLPGAGIPPPPP---------LPGVGIPPPPPLPGVGIPPPPPLP--GAGIP 1207
Query: 1538 APPP------------PLPPQPPPPPPPPPVEPTKLP 1562
PPP PLPP P PPPP+ P P
Sbjct: 1208 PPPPLPGMGIPPAPAPPLPP-PGTGIPPPPLLPVSGP 1243
Score = 87.8 bits (216), Expect = 9e-17
Identities = 123/430 (28%), Positives = 139/430 (32%), Gaps = 109/430 (25%)
Query: 348 GSSDLPFGAVGGTGGSSGPPFKAQPQDSATFAHTPPPAQATPAPGFKSAFSPYQTPVAHF 407
G+ LP + G G PP A PPP P PG P P A
Sbjct: 928 GAGILPLPPLPGAGIPPPPPLPG--------AAIPPPP---PLPGAGIPLPP-PLPGAGI 975
Query: 408 PPPPEEPTATAAFGARDSGEFRRAPAPPPLPPAEPLAKEKPGTPPGPPPPDTNSMELGGR 467
PPPP P A P PPPLP A G PP PP P
Sbjct: 976 PPPPPLPGAGI-------------PPPPPLPGA--------GIPPPPPLPGAGIPPPPPL 1014
Query: 468 PTFGWSPEP----CDSPGTPTLESSPAGPEKPHDSLDSRIEMLLKEQRTKLLFLREPDSD 523
P G P P P P L + P P
Sbjct: 1015 PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP---------------------------- 1046
Query: 524 TELQMEGSPISSSSSQLSPLAPFGTNSQPGFRGPTPPSSRPSSTGLEDISPTPLPDSDED 583
+ G+ I PL G P G P P G P PLP +
Sbjct: 1047 ----LPGAGIPPPP----PLPGAGIPPPPPLPGAGIPPP-PPLPGAGIPPPPPLPGAGIP 1097
Query: 584 EELDL-GLG-PRPPPEPGP--PDPAGLLSQTAEVALDLVGDRTPTSEKMDEGQQSSGEDM 639
L G+G P PPP PG P P L L G P +
Sbjct: 1098 PPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIP----- 1152
Query: 640 EISDDEMPSAPITSADCPKPMVVTPGAAAVAAPSVLAPTLPLPPPP-----GFPPLPPPP 694
P P+ A P P + PGA P + P + +PPPP G PP PP P
Sbjct: 1153 -------PPPPLPGAGIPPPPPL-PGAGIPPPPPL--PGVGIPPPPPLPGVGIPPPPPLP 1202
Query: 695 ----PPPPPQPGFPMPP---PLPPPPP---PPPPAHPAVTVPPPPLPAPPGVPPPPILPP 744
PPPPP PG +PP P PPP PPPP P P P +P P +
Sbjct: 1203 GAGIPPPPPLPGMGIPPAPAPPLPPPGTGIPPPPLLPVSGPPLLPQVGSSTLPTPQVCGF 1262
Query: 745 L-PPFPPGLF 753
L PP P GLF
Sbjct: 1263 LPPPLPSGLF 1272
Score = 84.7 bits (208), Expect = 8e-16
Identities = 144/547 (26%), Positives = 188/547 (34%), Gaps = 122/547 (22%)
Query: 1093 DSDEEETVSIVTSKAEATSSSESSESSEFESSSESSPSSSEDEEEVVAREEEEEEEEEEM 1152
D D+ T + V+ + SE S PS DEE R E+ E E +
Sbjct: 594 DQDQLYTWAAVSQPTHSLDYSEGQFPRRVPSMGP--PSKPPDEEH---RLEDAETESQSA 648
Query: 1153 VAEESMASAGPE-----DFEQDGEEAALAPGAPAVDSLGMEEEVDIETEAVAPEERPSML 1207
V+E + D + +G+ + ++ D+ T+ E + L
Sbjct: 649 VSETPQKRSDAVQKEVVDMKSEGQATVIQQLEQTIE--------DLRTKIAELERQYPAL 700
Query: 1208 DEPPLPVGVEEPADSREPPEEPGLSQEGAMLLSPEPPAKEVEARPPLSPERAPEHDLEVE 1267
D E A + E G++ G + L A +E + ++
Sbjct: 701 DT--------EVASGHQGLEN-GVTASGDVCLE----ALRLEEKEVRHHRILEAKSIQTS 747
Query: 1268 P-EPPMMLPLPLQPPLPPPRPPRPPSPPPEPETTDASHPSVPPEP-------------LA 1313
P E +L LP LP RPP PP P+T S S+ P +
Sbjct: 748 PTEEGGVLTLPPVDGLPG-RPPCPPGAESGPQTKFCSEISLIVSPRRISVQLDSHQPTQS 806
Query: 1314 EDHPPHTPGLCGSLAKSQSTETVPATPGGEPPLSGGS----------SGLSLSSPQVPGS 1363
PP P L S + Q PG +PP S + S +S +P S
Sbjct: 807 ISQPPPPPSLLWSAGQGQ--------PGSQPPHSISTEFQTSHEHSVSSAFKNSCNIP-S 857
Query: 1364 PFSYPAPSPSLSSGGL-------PRTPGRDFSFTPTFSEPSGPLL------------LPV 1404
P P S S GL P PG P+ + P P L LP
Sbjct: 858 PPPLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPG 917
Query: 1405 CPLPTGRRDERSGPLASPVLLETGLPLPLPLP---LPLPLALPAVLRAQARAPTPLPPLL 1461
+P +G L P L G+P P PLP +P P LP A PLPP L
Sbjct: 918 AGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPG-------AGIPLPPPL 970
Query: 1462 PAPLASCPPPMKRKPGRPRRSPPSMLSLDGPLVRPPAGAALGRELLLLPGQPQTPVFPST 1521
P PPP+ PG PP + P P GA G P P P
Sbjct: 971 PGAGIPPPPPL---PGAGIPPPPPLPGAGIPPPPPLPGA----------GIPPPPPLPGA 1017
Query: 1522 HDPRTVTLDFRNAGIPAPPPPLPPQ--PPPP-------PPPPPVEPTKLPFKELDNQWPS 1572
P L AGIP PPPPLP PPPP PPPPP+ +P P
Sbjct: 1018 GIPPPPPLP--GAGIP-PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIP---PPPPLPG 1071
Query: 1573 EAIPPGP 1579
IPP P
Sbjct: 1072 AGIPPPP 1078
Score = 45.1 bits (105), Expect = 7e-04
Identities = 49/163 (30%), Positives = 62/163 (38%), Gaps = 45/163 (27%)
Query: 1210 PPLP-VGVEEP-----ADSREPPEEPGLSQEGAMLLSPEPPAKEVEARPPLSPERAPEHD 1263
PPLP VG+ P A PP PG + P PP V PP P
Sbjct: 1144 PPLPRVGIPPPPPLPGAGIPPPPPLPGAG------IPPPPPLPGVGIPPP-----PPLPG 1192
Query: 1264 LEVEPEPPMM-LPLPLQPPLP---------PPRPPRPPSPPPEPETTDASHPSVPPEPLA 1313
+ + P PP+ +P PPLP PP PP P + P P S P + P+ +
Sbjct: 1193 VGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPP-PGTGIPPPPLLPVSGPPLLPQVGS 1251
Query: 1314 EDHPPHTPGLCGSLAKSQSTETVPATPGGEPPLSGGSSGLSLS 1356
P TP +CG L PPL G GL ++
Sbjct: 1252 STLP--TPQVCGFL---------------PPPLPSGLFGLGMN 1277
Score = 44.3 bits (103), Expect = 0.001
Identities = 52/170 (30%), Positives = 56/170 (32%), Gaps = 44/170 (25%)
Query: 1456 PLPPLLPAPLASCPPPMKRKPGRPRRSPPSMLSLDGPLVRPPAGAALGRELLLLPGQPQT 1515
P PP LP C PG PP PP LPG
Sbjct: 856 PSPPPLP-----CTESSSSMPGLGMVPPPP----------PP-----------LPGMT-V 888
Query: 1516 PVFPSTHDPRTVTLDFRNAGIPAPPPPLPPQPPPPPPPPPVEPTKLPFKELDNQWPSEAI 1575
P PST P+ L +P PPPPLP PPPPP P LP L P I
Sbjct: 889 PTLPSTAIPQPPPLQGTEM-LPPPPPPLPGAGIPPPPPLPGAGI-LPLPPL----PGAGI 942
Query: 1576 PPGPRGRDEVTEEYMELAKSRGPWRRPPKKRHEDLVPPAGSPELSPPQPL 1625
PP P L + P P L PP + PP PL
Sbjct: 943 PPPP-----------PLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPL 981
Score = 38.5 bits (88), Expect = 0.064
Identities = 95/433 (21%), Positives = 140/433 (32%), Gaps = 96/433 (22%)
Query: 200 QTLPVGELDAVSPIVNETLQLSDALKRLKDGGLS----------AGCGSGSSSVTPNSGG 249
Q L GELD+ ++ +T LS + + GLS G G G GG
Sbjct: 101 QALQTGELDSAHSLLTKTPDLSLSAD---EAGLSDTECADPFEVTGPG-GPGPAEARVGG 156
Query: 250 TPFSQDTAYSSCRLDTPN-SYGQGTPLTPRLGTPFSQDSSYSSRQPTPSYLFSQDPAVTF 308
P ++D ++ D S G T + S+ S L A+
Sbjct: 157 RPIAEDVETAAGAQDGQRTSSGSDTDIY-----------SFHSATEQEDLLSDIQQAIRL 205
Query: 309 KARRHESKFTDAYNRRHEHHYVH-NSPAV--TAVAGATAAFRGSSDLPFGAVGGTGGSSG 365
+ ++ + ++ + PA TAV+ AF G G GG G + G
Sbjct: 206 QQQQQQQLQLQLQQQQQQQQLQGAEEPAAPPTAVSPQPGAFLGLDRFLLGPSGGAGEAPG 265
Query: 366 PPFKAQPQDSATFAHTPPPAQATPAPGFKSAFSPYQTPVAHFPPPPEEPTATAAFGARDS 425
P Q SA S +A P P++P + ++
Sbjct: 266 SPDTEQAL---------------------SALSDLPESLAAEPREPQQPPSPGGLPVSEA 304
Query: 426 GEFRRAPAPPPLPPAEPLAKEKPGTPPGPPPPDTNSMELGGRPTFGWSPEPCDSPGTPTL 485
P LP A+P AK+ P + P P E G P G + + +
Sbjct: 305 ---------PSLPAAQPAAKDSPSSTAFPFPEAGPGEEAAGAPVRG-AGDTDEEGEEDAF 354
Query: 486 ESSPAG-------PEKPHDSLDSRIEMLLKEQRTKLLFLREPDSDTELQMEGSP------ 532
E +P G PE D+ E +E + PD+ + GSP
Sbjct: 355 EDAPRGSPGEEWAPEVGEDAPQRLGEEPEEE-------AQGPDAPAAASLPGSPAPSQRC 407
Query: 533 -----------ISSSSSQLSP---LAPFGTNSQPGF-RGPTPPSSRPSSTGLEDISPTPL 577
I +++ QLS N P R P P SR S T L ++ P
Sbjct: 408 FKPYPLITPCYIKTTTRQLSSPNHSPSQSPNQSPRIKRRPEPSLSRGSRTALASVA-APA 466
Query: 578 PDSDEDEELDLGL 590
D L GL
Sbjct: 467 KKHRADGGLAAGL 479
Score = 32.3 bits (72), Expect = 4.6
Identities = 31/130 (23%), Positives = 50/130 (38%), Gaps = 11/130 (8%)
Query: 1067 DSDDRDESENDDEDTALSEASEKDEGDSDEEETVSIVTSKAEATSSSESSESSEFESSSE 1126
D++ + +D ++ +E E + S VS S A +++ S SS E
Sbjct: 268 DTEQALSALSDLPESLAAEPREPQQPPSPGGLPVSEAPSLPAAQPAAKDSPSSTAFPFPE 327
Query: 1127 SSPSSSEDEEEVVAREEEEEEEEEEMVAEESMASAG-----------PEDFEQDGEEAAL 1175
+ P V + +EE EE+ + S G P+ ++ EE A
Sbjct: 328 AGPGEEAAGAPVRGAGDTDEEGEEDAFEDAPRGSPGEEWAPEVGEDAPQRLGEEPEEEAQ 387
Query: 1176 APGAPAVDSL 1185
P APA SL
Sbjct: 388 GPDAPAAASL 397
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 112 bits (279), Expect = 5e-24
Identities = 186/764 (24%), Positives = 256/764 (33%), Gaps = 157/764 (20%)
Query: 216 ETLQLSDALKRLKDGGLSAGCGSGSSSVTPNSGGTPFSQDTAYSSCRLDTPNSYGQGTPL 275
ET+ A + K LSAG +S TP + ++ + + + P P
Sbjct: 140 ETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPR 199
Query: 276 TPRLGT--PFSQDSSYSSRQPTPSYLFSQDPAVTFKARRHESKFTDAYNRRHEHHYVHNS 333
P G S S +S+ +P+P+ ARR S R ++
Sbjct: 200 PPTEGPRKSVSSASEHSTTEPSPA------------ARRRPSA-GGGLQRPASRSLSSSA 246
Query: 334 PAVTAVAGATAAFRGSSDLPF-----------------------GAVGGTGGSSGPPFKA 370
+++ A + + RG+ P A G S P A
Sbjct: 247 TPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPL-A 305
Query: 371 QPQDSATFAHTPPPAQ--ATPAPGFKSAFSPYQTPVAHFPPPPEEPTATAAFGARDSGEF 428
P S T A PP ATP P P TP+ PP P P +
Sbjct: 306 TPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPS-----------L 354
Query: 429 RRAPAPPPLPPAEPLAKEKPGTPPGPPPPD--------------TNSMELGGRPTFGWSP 474
+ P+PP PP++ A TPP PP + S++ P S
Sbjct: 355 QTLPSPPATPPSQ--APPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSL 412
Query: 475 EPCDSPGTPTLESSPA----GPEKPHDSLDSRIEMLLKEQ-----RTKLLFLREPDSDTE 525
+ S G+PTL+++ + P + SL S + L P T
Sbjct: 413 QATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTS 472
Query: 526 LQMEGSPIS-----------SSSSQLSPLAPFGT------NSQPGFRGP---TPPSS--R 563
L SP+S SS + SP AP + +Q P TPP+S
Sbjct: 473 LSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTT 532
Query: 564 PSSTGLEDISPTPLPDSD---EDEELDLGLGPRPPPEPGPPDPAGLLSQTAEVALDLVGD 620
P L ++P PL + L+ P P P PP P ++
Sbjct: 533 PPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPP 592
Query: 621 RTPTSEKMDEGQQSSGEDMEISDDEMPSAP----ITSADCPKPMVVTPGAAAVAAPSVLA 676
+ P + Q + P AP + P +P + +A PS A
Sbjct: 593 QAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQA 652
Query: 677 PTL-------------PLPP------PPGFPPLPPPPPPPPPQPGFPMPPPL--PPPPPP 715
P P PP PP PP+ P PP P PPL PP PP
Sbjct: 653 PNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPA 712
Query: 716 PPPAHPAVTVP---PPPLPAPP-GVPP-PPILPPLPPF---PPGLFPVMQVDMSHVLGGQ 767
PP P+ T P PPPL APP VPP PP PP+ P PP + P++ V
Sbjct: 713 SPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSP 772
Query: 768 WGGMPMSFQMQTQVLSRLMTGQGACPYPPFMAAAAAAASAGLQFVNLPPYRGPFSLSNSG 827
+PMS + A PP A + AS P + PFS S S
Sbjct: 773 PASLPMS-----PLAKPPPQAPPALATPPLQALPSPPASF--------PGQAPFSPSASL 819
Query: 828 PGRGQHWPPLPKFDP-------SVPP-PGYMPRQEDPHKATVDG 863
P PP P+ P VPP P P + P + G
Sbjct: 820 PMSPLATPP-PQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPG 862
Score = 112 bits (279), Expect = 5e-24
Identities = 128/467 (27%), Positives = 170/467 (36%), Gaps = 76/467 (16%)
Query: 1225 PPEEPGLSQEGAMLLSP--EPPAKEVEARPPLSPERAPEH-DLEVEPEPPMMLPLPLQPP 1281
PP + G + SP P +ARP P+ A + P PP+ PLPL PP
Sbjct: 287 PPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPP 346
Query: 1282 LPPPRP-----PRPPSPPPEPETTDASHPSVPPEPLAEDHPP-------HTPGLCGSLAK 1329
P P P PP+ PP + P + P + PP +P L +
Sbjct: 347 SPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSP 406
Query: 1330 SQSTETVPATPGGEPPLSGGSSGLSLSSPQV------PGSPFSYPAPSPSLSSG-GLPRT 1382
+ T G P L S L++S Q P P S P SP L + LP +
Sbjct: 407 LALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPAS 466
Query: 1383 PGRDFSFTPTFSEPSGPLLL-PVCPLPTGRRDERSGPLAS----PVLLETGLPLPLPLPL 1437
P S +P S S PL + P+ L + PL+S P+ ++ L P
Sbjct: 467 PPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTP 526
Query: 1438 PLPLALPAVLRAQARAPTPL--------------PPL-LPAPLASCPPPMKRKPGR---- 1478
P L P + + AP PL PP P PL + P P+ P
Sbjct: 527 PASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSS 586
Query: 1479 ----PRRSPPSMLS--LDG-------PLVRPPAGAALGRELLLLPGQPQTPVFPSTHDPR 1525
P ++PP++ S L G PL PP A L L P P P
Sbjct: 587 IATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLA 646
Query: 1526 TVTLDFRNA------GIPAPPPPLPPQPPP--PPPPPPVEPTKLPFKELDNQW--PSEAI 1575
T + NA P PPP PP P PP PPV P+ P + P +
Sbjct: 647 TPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQV 706
Query: 1576 PPGPRGRDEVTEEYMELAKSRGPWRRPPKKRHEDLVPPAGSPELSPP 1622
PP P ++ ++ P PP + VPP SP SPP
Sbjct: 707 PPSPPASPPMSPSATPPPQAPPPLAAPPLQ-----VPP--SPPASPP 746
Score = 107 bits (268), Expect = 9e-23
Identities = 131/436 (30%), Positives = 167/436 (38%), Gaps = 75/436 (17%)
Query: 1209 EPPLPVGVEEPADSREPPEEPGLSQEGAMLLSPEPPAKEVEARPPLSPERAPEHDLEVEP 1268
+ PL + P +++ P L A L +P A PPL AP +E
Sbjct: 501 QAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLET 560
Query: 1269 EPPMMLPLPLQPPLPP--PRPPRPPS----PPPEPETTDASHP-----SVPPEPLAEDHP 1317
PP P PLQ P P PP PS PPP+ AS P S P PLA P
Sbjct: 561 -PPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPP 619
Query: 1318 PHTPGLCGSLAKSQSTETVPATPGGEPPLSGGSSGLSLSSPQVPGS--------PFSYPA 1369
P L +L Q+ P +P PPLS L+ SPQ P + PFS P
Sbjct: 620 QAPPXL--ALPPLQA----PPSPPASPPLSP----LATPSPQAPNALAVHLLQAPFS-PP 668
Query: 1370 PSPSLSSGGLPRTPGRDFSFTPTFSEPS-GPLLLPVCPLPTGRRDERSGPLASPVLLETG 1428
PSP + + P +P +P+ + PS P L PL S P++
Sbjct: 669 PSPPVQA---PFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQ 725
Query: 1429 LPLPLPLP-LPLPLALPAV--LRAQARAPTPLPPLLPAPLASCPPPMKRKPGRPRRSPPS 1485
P PL P L +P + PA + A P +PPLL AP PP SPP+
Sbjct: 726 APPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPP-----------SPPA 774
Query: 1486 MLSLDGPLVRPPAGAALGRELLLLPGQPQTPVFPSTHDPRTVTLDFRNAGIPAPPPPLPP 1545
L + PL +PP A L P P P + + + + PPP PP
Sbjct: 775 SLPMS-PLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPP 833
Query: 1546 QPPPP----PPPPPVEPTKLPFKELDNQWPSEAIPPGPRGRDEVTEEYMELAKSRGPWRR 1601
P PP PP PT Q P PP P V+ + LA + GP
Sbjct: 834 VLAAPLLQVPPSPPASPTL--------QAPRR--PPTPGPDTSVSGPRLTLALAPGP--- 880
Query: 1602 PPKKRHEDLVPPAGSP 1617
PP PP+ SP
Sbjct: 881 PP--------PPSRSP 888
Score = 106 bits (265), Expect = 2e-22
Identities = 111/368 (30%), Positives = 148/368 (40%), Gaps = 43/368 (11%)
Query: 1197 AVAPEERPSMLDEP-PLPVGVEEPAD--SREPPEEPGLSQEGAMLLSPEPPAKEVEARPP 1253
A AP P + P P P ++ P + PPE P + + +P P A A PP
Sbjct: 549 ASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETP------SSIATPPPQAPPALASPP 602
Query: 1254 L----SPERAPEHDLEVEPEPPMMLPLPLQ-PPLPPPRPPRPPSPPPEPETTDASHPSVP 1308
L SP +P + P + LP PLQ PP PP PP P P P+ +A +
Sbjct: 603 LQGLPSPPLSPLATPPPQAPPXLALP-PLQAPPSPPASPPLSPLATPSPQAPNALAVHLL 661
Query: 1309 PEPLAEDHPPHTPGLCGSLAKSQSTETVPATPGGEPPLSGGSSGLSLSSPQVPGSPFSYP 1368
P + PP +P + + S P +P PP S L+ QVP SP + P
Sbjct: 662 QAPFS---PPPSPPVQAPFSPPASP---PVSPSATPP-SQAPPSLAAPPLQVPPSPPASP 714
Query: 1369 APSPSLSSGGLPRTPGRDFSFTPTFSEPSGPLLLPVCPLPTGRRDERSGPLASPVLLETG 1428
SPS + P+ P + P PS P P+ P T P P+L
Sbjct: 715 PMSPSATPP--PQAPP-PLAAPPLQVPPSPPASPPMSPSAT------PPPRVPPLLAAPP 765
Query: 1429 LPLPLPLPLPLPLALPAVLRAQARAPTPLPPLLPAP-LASCPPPMKRKPGRPRRSPPSML 1487
L +P P LP++ A+ P PP L P L + P P PG+ SP + L
Sbjct: 766 LQVPPSPPASLPMS------PLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASL 819
Query: 1488 SLDGPLVRPPAGA--ALGRELLLLPGQPQTPVFPSTHDPRTVTLDFRNAGIPAPPPPLPP 1545
+ PL PP A L LL +P P P P+ PR + + P L
Sbjct: 820 PMS-PLATPPPQAPPVLAAPLLQVP--PSPPASPTLQAPRRPPTPGPDTSVSGPRLTLAL 876
Query: 1546 QPPPPPPP 1553
P PPPPP
Sbjct: 877 APGPPPPP 884
Score = 88.2 bits (217), Expect = 7e-17
Identities = 114/382 (29%), Positives = 133/382 (34%), Gaps = 60/382 (15%)
Query: 1197 AVAPEERPSMLDEPPLPVGVEEPADSR-EPPEEPGLSQEGAM----LLSPEPPAKEVEAR 1251
A P + P L PPL PA P P A+ L +P P +
Sbjct: 615 ATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQ 674
Query: 1252 PPLSPERAPEHDLEVEPE---PPMMLPLPLQ-PPLPPPRPPRPPS--PPPEPETTDASHP 1305
P SP +P P PP + PLQ PP PP PP PS PPP+ A+ P
Sbjct: 675 APFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPP 734
Query: 1306 -SVPPEPLAEDHPPHTPGLCGSLAKSQSTETVPATPGGEPPLSGGSSGLSLSSPQVP--- 1361
VPP P A PP +P P PP S S L+ PQ P
Sbjct: 735 LQVPPSPPAS--PPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPAL 792
Query: 1362 GSPFSYPAPSPSLSSGGLPRTPGRDFSFTPTFSEPSGPLLLPVCPLPTGRRDERSGPLAS 1421
+P PSP S G F+P+ S P PL P P A
Sbjct: 793 ATPPLQALPSPPASFPG-------QAPFSPSASLPMSPLATP-------------PPQAP 832
Query: 1422 PVLLETGLPLPLPLPLPLPLALPAVLRAQARAPTPLP------PLLPAPLASCPPPMKRK 1475
PVL L +P P P A P L+A R PTP P P L LA PPP
Sbjct: 833 PVLAAPLLQVP-----PSPPASP-TLQAPRRPPTPGPDTSVSGPRLTLALAPGPPP---- 882
Query: 1476 PGRPRRSPPSMLSLDGPLVRPPAGAALGRELLLLPGQPQTPVFPSTHDPRTVTLDFRNAG 1535
P RSP S LS + + EL P+ S + A
Sbjct: 883 --PPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAW 940
Query: 1536 IPAPPPPL-----PPQPPPPPP 1552
P PPL P P P PP
Sbjct: 941 SRGPAPPLAFRGAPGAPLPWPP 962
Score = 86.7 bits (213), Expect = 2e-16
Identities = 111/374 (29%), Positives = 143/374 (38%), Gaps = 61/374 (16%)
Query: 367 PFKAQPQDSATFAHTPPPAQATPA---PGFKSAFSPYQTPVAHFPPPPEEPTATAAFGAR 423
P P ++ + TPPP QA PA P + SP +P+A PPP+ P A
Sbjct: 575 PLTTPPPETPSSIATPPP-QAPPALASPPLQGLPSPPLSPLA--TPPPQAPPXLAL---- 627
Query: 424 DSGEFRRAPAPPPLPPAEPLAKEKPGTPPGPPPPDTNSMELGGRPTFGWSPEPCDSPGTP 483
+ P+PP PP PLA P P P+ ++ L P +SP P SP
Sbjct: 628 --PPLQAPPSPPASPPLSPLAT------PSPQAPNALAVHLLQAP---FSPPP--SPPVQ 674
Query: 484 TLESSPAGPE-KPHDSLDSRIEMLLKEQRTKLLFLREPDSDTELQMEGSPISSSSSQLSP 542
S PA P P + S+ L L+ P S SP S S+ P
Sbjct: 675 APFSPPASPPVSPSATPPSQAPPSLAAPP-----LQVPPSPP-----ASPPMSPSATPPP 724
Query: 543 LAPFGTNSQPGFRGPTPPSSRPSSTGLEDISPTPLPDSDEDEELDLGLGPRPPPEPGPPD 602
AP + P P+PP+S P S P +P L + P PP P
Sbjct: 725 QAPPPLAAPPLQVPPSPPASPPMSPSATP--PPRVPPLLAAPPLQV---PPSPPASLPMS 779
Query: 603 PAGLLSQTAEVALDLVGDRTPTSEKMDEGQQSSGEDMEISDDEMPSAPITSADCPKPMVV 662
P A AL TP + + S + P +P SA P +
Sbjct: 780 PLAKPPPQAPPAL-----ATPPLQALPSPPASF-------PGQAPFSP--SASLPMSPLA 825
Query: 663 TPGAAAVAAPSVLAPTLPLPP-PPGFPPLPPPPPPPPPQPGFPMPPP-----LPPPPPPP 716
TP A P + AP L +PP PP P L P PP P P + P L P PPPP
Sbjct: 826 TPPPQA--PPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPP 883
Query: 717 PPAHPAVTVPPPPL 730
P P+ T+ P L
Sbjct: 884 PSRSPSSTLSGPDL 897
Score = 86.3 bits (212), Expect = 3e-16
Identities = 123/450 (27%), Positives = 160/450 (35%), Gaps = 102/450 (22%)
Query: 1198 VAPEERPSMLDEPPLPVGVEEPADSREPPEEPGLSQEGAMLLSPEPPAKEVEARPPLSPE 1257
++P + + L P P PP+ P L A L P P + P +SP
Sbjct: 432 MSPRQTQASLTSPSRPAST--------PPDSPPLQ---APLSLPASPPLQTSLSPAVSPL 480
Query: 1258 RAPE--HDLEV-------EPEPPM----MLPLPLQPPLPPPRPPRPPSPPPEPETTDASH 1304
+P H L+ P+ P+ M PL Q L PP PP+ P +
Sbjct: 481 SSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENL-- 538
Query: 1305 PSVPPEPLAEDHPPHTPGLCGSLAKSQSTETVPATPGGEPPLSGGSSGLSLSSPQVPGSP 1364
PS+ P PL P T + ET P PL S L+ P+ P S
Sbjct: 539 PSLAPPPLQTASAPLT---------TPHLETPPCP--APCPLQAPPSPLTTPPPETPSSI 587
Query: 1365 FSYPAPSPSLSSG----GLPRTPGRDFSFTPTFSEPSGPLLLPVCPLPTGRRDERSGPLA 1420
+ P +P + GLP P + P P P P LP PL
Sbjct: 588 ATPPPQAPPALASPPLQGLPSPPLSPLATPP----PQAP---PXLALP---------PLQ 631
Query: 1421 SPVLLETGLPLPLPLPLPLPLALPAVLRAQARAPTPLPP-LLPAPLASCPPPMKRKPGRP 1479
+P P P P PLA P+ +AP L LL AP + P P + P P
Sbjct: 632 AP-------PSPPASPPLSPLATPS-----PQAPNALAVHLLQAPFSPPPSPPVQAPFSP 679
Query: 1480 RRSPPSMLSLDGPLVRPPAGAALGRELLLLPGQPQTP-VFPSTHDPRTVTLDFRNAGIPA 1538
SPP S P PP+ AA L + P P +P + PS P P
Sbjct: 680 PASPPVSPSATPPSQAPPSLAA--PPLQVPPSPPASPPMSPSATPP------------PQ 725
Query: 1539 PPPPL--PP--QPPPPPPPPPVEPTKLPFKELDN--QWPSEAIPPGPRGRDEVTEEYMEL 1592
PPPL PP PP PP PP+ P+ P + P +PP P
Sbjct: 726 APPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSP-----------PA 774
Query: 1593 AKSRGPWRRPPKKRHEDLVPPAGSPELSPP 1622
+ P +PP + L P SPP
Sbjct: 775 SLPMSPLAKPPPQAPPALATPPLQALPSPP 804
Score = 78.2 bits (191), Expect = 7e-14
Identities = 106/371 (28%), Positives = 140/371 (37%), Gaps = 40/371 (10%)
Query: 1278 LQPPLPPPRPPRPPSPPPEPETTDAS-HPSVPPEPLAEDHPPHTPGLCGSLAKSQSTETV 1336
L P P R PRPP+ P + AS H + P P A P GL ++S S+
Sbjct: 189 LPRPAPSAR-PRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSS-- 245
Query: 1337 PATPGGEPPLSGGSSGLSLSSPQVPGSPFSYPAPSPSLSSGGLPRTPGRDFSFTPTFSEP 1396
ATP P SG S + +P+ P P S P P + TP R +
Sbjct: 246 -ATPLSSPARSGPS---ARGTPRAPAHP-SQPKPKGLQALRPPQVTPPRKDAAPALGPLS 300
Query: 1397 SGPLLLPVCPLPTGRRDERSGPLASPVLLETGLPLPL----PLPLPLPLALPAVLRAQAR 1452
S PL P P+G ++ P+ P T LP L PL PLPLA P+ +
Sbjct: 301 SSPL---ATPSPSG---TKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSL 354
Query: 1453 APTPLPPLLP---APLASCPPPMKRKPGRPRRSPPSML--SLDGP-LVRPPAGAALGREL 1506
P PP P AP + PPM+ P + PP + SL P L PP+ AL
Sbjct: 355 QTLPSPPATPPSQAPPSMTTPPMQAPPSL-QTIPPIQVPHSLTSPSLQAPPSPLALSS-- 411
Query: 1507 LLLPGQPQTPVFPSTHDPRTVTLDFRNAGIPAPPPPLPPQPPPPPPPPPVEPTKLPFKEL 1566
L +P +TH T++ A + +P P PP PP P LP
Sbjct: 412 LQATTSLGSPTLQATHSFLTMSPRQTQASLTSPS---RPASTPPDSPPLQAPLSLPASPP 468
Query: 1567 DNQWPSEAIPPGPRGRDEVTEEYMELAKSRGPWR------RPPKKRHEDLVPPAGSPELS 1620
S A+ P + + S P PP + L PP+ +
Sbjct: 469 LQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQ---T 525
Query: 1621 PPQPLFRPRSE 1631
PP L P E
Sbjct: 526 PPASLTTPPLE 536
Score = 76.6 bits (187), Expect = 2e-13
Identities = 107/404 (26%), Positives = 139/404 (34%), Gaps = 45/404 (11%)
Query: 385 AQATPAPGFKSAFSPYQTPVAHFPPPPEEPTATAAFG----------ARDSGEFRRAPAP 434
A TPA +P + P + PPPP P A G A +G A P
Sbjct: 13 AARTPAARAPGLLTP-RPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIP 71
Query: 435 PPLPPAEPLAKEKPGT-PPGPPPPDTNSMELGGRPTFGWSPEPCDSPG--TPTLESSPAG 491
P A P + P PP + E P SP P SPG + T P G
Sbjct: 72 ESAPRAGPTRSAGTSSRNPASRPPASGRGE-RAPPAKNTSPGPVSSPGRASGTTRPGPLG 130
Query: 492 PEKPHDSLDSRIEMLLKEQRTKLLFLRE-PDSDTELQMEGSPISSSSSQLSPLAPFGTNS 550
+ S + + + K L DT G+P S + ++ S A +
Sbjct: 131 QKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTP-SPAMARRSRAA----GT 185
Query: 551 QPGFRGPTPPSSRPSSTGLEDISPTPLPDSDEDEELDLGLGPRPPPEPGPPDPAGLLSQT 610
+ G P PS+RP PT P + P P G L +
Sbjct: 186 EVGLPRPA-PSARPR-------PPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRP 237
Query: 611 AEVALDLVGDRTPTSEKMDEGQQSSGEDMEISDDEMPSAPITSADCPKPMVVTPGAAAVA 670
A +L TP S G + G + P A P P V P A
Sbjct: 238 ASRSLS--SSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRP-PQVTPPRKDAAP 294
Query: 671 APSVLAPT-LPLPPPPGFP--PLPPP-------PPPPPPQPGFPMPPPLPPPPPPPPPAH 720
A L+ + L P P G P+PPP P PP P P PL PP P PP+
Sbjct: 295 ALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPS- 353
Query: 721 PAVTVPPPPLPAPPGVPPPPILPPLPPFPPGLFPVMQVDMSHVL 764
T+P PP P PP PP+ PP L + + + H L
Sbjct: 354 -LQTLPSPPATPPSQAPPSMTTPPMQA-PPSLQTIPPIQVPHSL 395
Score = 61.2 bits (147), Expect = 9e-09
Identities = 111/422 (26%), Positives = 138/422 (32%), Gaps = 102/422 (24%)
Query: 1275 PLPLQPPLPPPRPPRPPSPPPEPETTDA-----SHPSVPPEPLAEDHPPHTPGLCGS--- 1326
P P L PRPP P PPP P T A + +V +PLAE G+ G+
Sbjct: 17 PAARAPGLLTPRPPGSPRPPP-PVTPAALRVLGAAGAVGRKPLAE----RAGGIGGATIP 71
Query: 1327 -----LAKSQSTETVPATPGGEPPLSGGSSGLSLSSPQVPGSPFSYPAPSPSLSSGGLPR 1381
++S T P PP SG + PG P S P + + G
Sbjct: 72 ESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPG-PVSSPGRASGTTRPGPLG 130
Query: 1382 TPGRDFSFTPTFSEPSGPLLLPVCPLPTGRRDERSGP---LASPVL--------LETGLP 1430
G S T + L G R + SGP SP + E GLP
Sbjct: 131 QKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLP 190
Query: 1431 LPLPLPLPLP---------------------------------LALPAVLRAQARAPTPL 1457
P P P P L PA R+ + + TPL
Sbjct: 191 RPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPA-SRSLSSSATPL 249
Query: 1458 -PPLLPAPLASCPPPMKRKPGRPRRSPPSMLSLDGPLVRPP---AGAALGRELLLLPGQP 1513
P P A P P +P+ P + +L P V PP A ALG L P
Sbjct: 250 SSPARSGPSARGTPRAPAHPSQPK--PKGLQALRPPQVTPPRKDAAPALGP----LSSSP 303
Query: 1514 QTPVFPSTHDPRTV-TLDFRNAGIPAPPPPLPPQPPPPP--PPPPVEPTKLPFKELDNQW 1570
PS R V D +PA PP PP P P PP P P L
Sbjct: 304 LATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPAT 363
Query: 1571 PSEAIPPGPRGRDEVTEEYMELAKSRGPWRRPPKKRHEDLVPP------AGSPEL-SPPQ 1623
P PP + + P + PP + +PP SP L +PP
Sbjct: 364 PPSQAPP---------------SMTTPPMQAPPSLQ---TIPPIQVPHSLTSPSLQAPPS 405
Query: 1624 PL 1625
PL
Sbjct: 406 PL 407
Score = 52.0 bits (123), Expect = 6e-06
Identities = 62/238 (26%), Positives = 85/238 (35%), Gaps = 34/238 (14%)
Query: 366 PPFKAQPQDSATFAHTPPPAQATPAPGFKSAFSPYQTPVAHFPPPPEEPTATAAFGARDS 425
PP +A P A+F P QA +P SP TP PP P
Sbjct: 795 PPLQALPSPPASF-----PGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQV------- 842
Query: 426 GEFRRAPAPPPLPPAEPLAKEKPGTPPGPPPPDTNSMELGGRPTFGWSPEPCDSPGTPTL 485
PP PPA P + P PP P ++ G R T +P P P + +
Sbjct: 843 ---------PPSPPASPTLQ----APRRPPTPGPDTSVSGPRLTLALAPGP-PPPPSRSP 888
Query: 486 ESSPAGPEKPHDSLDSRI---EMLLKEQRTKLLFLREPDSDTELQMEGSPISSSSSQLSP 542
S+ +GP+ S + E+ + + P D EL + ++ P
Sbjct: 889 SSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAEL----AACHPAAWSRGP 944
Query: 543 LAPFGTNSQPGFRGPTPPSSRP-SSTGLEDISPTPLPDSDEDEELDLGLGPRPPPEPG 599
P PG P PP++ P S+ GL I T P+S L GP P G
Sbjct: 945 APPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGG 1002
Score = 48.1 bits (113), Expect = 8e-05
Identities = 69/255 (27%), Positives = 87/255 (34%), Gaps = 71/255 (27%)
Query: 1197 AVAPEERPSMLDEPPLPVGVEEPAD------SREPPEEPGLSQEGAMLLSPEPPAKEVEA 1250
A P P +L PPL V PA ++ PP+ P + P PPA
Sbjct: 751 ATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPAS-FPG 809
Query: 1251 RPPLSPERA-PEHDLEVEPE---PPMMLPLPLQPPLPPPRPP-----RPPSPPPE----- 1296
+ P SP + P L P P + PL PP PP P RPP+P P+
Sbjct: 810 QAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSG 869
Query: 1297 PETTDASHPSVPPEPLAEDHPPHT---PGLCGSLAKSQSTET------------VPATP- 1340
P T A P PP P P T P L G + + ST A+P
Sbjct: 870 PRLTLALAPGPPPPPSRS--PSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPP 927
Query: 1341 ---------------GGEPPLS-GGSSGLSLSSP---------------QVPGSPFSYPA 1369
G PPL+ G+ G L P + G + PA
Sbjct: 928 PDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPA 987
Query: 1370 PSPSLSSGGLPRTPG 1384
P +L G P T G
Sbjct: 988 PG-ALDPGPSPGTSG 1001
Score = 34.3 bits (77), Expect = 1.2
Identities = 49/185 (26%), Positives = 67/185 (36%), Gaps = 37/185 (20%)
Query: 333 SPAVTAVAGATAAFRGSSDLPFGAVGGTGGSSGPPFKAQPQDSATFAHTPP--PAQAT-- 388
+P + A+ A+F G + A + PP +A P +A PP PA T
Sbjct: 794 TPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQ 853
Query: 389 -----PAPGFKSAFS-PYQT-PVAHFPPPPEEPTATAAFGARD-SGEFRRAPAPPPLPPA 440
P PG ++ S P T +A PPPP + ++ D +G A + P
Sbjct: 854 APRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTP----- 908
Query: 441 EPLAKEKPGTPPGP-------PPPDTNSMELGGRPTFGWSPEPC------DSPGTPTLES 487
+E G GP PPPD EL WS P +PG P
Sbjct: 909 ----EELRGYDSGPEGGAAASPPPDA---ELAACHPAAWSRGPAPPLAFRGAPGAPLPWP 961
Query: 488 SPAGP 492
GP
Sbjct: 962 PATGP 966
Score = 33.1 bits (74), Expect = 2.7
Identities = 30/107 (28%), Positives = 33/107 (30%), Gaps = 22/107 (20%)
Query: 667 AAVAAPSVLAPTLPLPPPPGFPPLPPPPPPP----------------PPQPGFPMPPPLP 710
AA P+ AP L P PPG P PPP P + G +P
Sbjct: 12 AAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIP 71
Query: 711 PPPPPPPPAHPAVTVPPPPLPAPPG------VPPPPILPPLPPFPPG 751
P P A T P PP PP P P PG
Sbjct: 72 ESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPG 118
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens]
Length = 816
Score = 104 bits (259), Expect = 9e-22
Identities = 124/426 (29%), Positives = 160/426 (37%), Gaps = 70/426 (16%)
Query: 1176 APGA-PAVDSLGMEEEVDIETEAVAPEERPSMLDEPPLPVGVEEPAD------------- 1221
AP A P + G + V +E E P+ P G++ PA
Sbjct: 184 APSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSP 243
Query: 1222 SREPPEEPGLSQEGAMLLSPEPPAKEVEARPPLSPER---APEHDLEVEPEPPMMLPLPL 1278
+R P G + A P+P + P ++P R AP L P+ P P
Sbjct: 244 ARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPA--LGPLSSSPLATPSPS 301
Query: 1279 QPPLPPPRP-----PRPPSPPPEPETTD-------ASH---PSVPPEPLAEDHPPHTPGL 1323
PP P P P PP+ PP TT A+H PS P PLA P P L
Sbjct: 302 APPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPAL 361
Query: 1324 CGSLAKSQSTETVPATPGGEPPLSGGSSGLSLSSPQVPGS--------PFSYPAPSPSLS 1375
+L Q+ P +P PPLS L+ SPQ P + PFS P P +
Sbjct: 362 --ALPPLQA----PPSPPASPPLSP----LATPSPQAPNALAVHLLQAPFSPPPSPPVQA 411
Query: 1376 SGGLPRTPGRDFSFTPTFSEPSGPLLLPVCPLPTGRRDERSGPLASPVLLETGLPLPLPL 1435
P +P S TP P L P +P P ASP + + P P
Sbjct: 412 PFSPPASPPVSPSATPPSQAPPS-LAAPPLQVPPS-------PPASPPMSPSATPPP--- 460
Query: 1436 PLPLPLALPAVLRAQARAPTPLPPLLPAPLASCPPPMKRKPGRPRRSPPSMLSLDGPLVR 1495
P PLA P + A+ P P L PL + P P PG+ SP + L + PL
Sbjct: 461 QAPPPLAAPPLQLAKPPPQAP-PALATPPLQALPSPPASFPGQAPFSPSASLPMS-PLAT 518
Query: 1496 PPAGA--ALGRELLLLPGQPQTPVFPSTHDPRTVTLDFRNAGIPAPPPPLPPQPPPPPPP 1553
PP A L LL +P P P P+ PR + + P L P PPPP
Sbjct: 519 PPPQAPPVLAAPLLQVP--PSPPASPTLQAPRRPPTPGPDTSVSGPRLTLA-LAPGPPPP 575
Query: 1554 PPVEPT 1559
P P+
Sbjct: 576 PSRSPS 581
Score = 95.5 bits (236), Expect = 4e-19
Identities = 149/581 (25%), Positives = 201/581 (34%), Gaps = 107/581 (18%)
Query: 333 SPAVTAVAGATAAFRGSSDLPFGAVGGTGGSS--------GPPFKAQPQDSATFAHTPPP 384
+PA V GA A G L A GG GG++ GP ++P S PP
Sbjct: 40 TPAALRVLGAAGAV-GRKPLAERA-GGIGGATIPESAPRAGPTRTSRPPASGRGERAPPA 97
Query: 385 AQATPAPGFKSAFSPYQTPVAHFPPP-PEEPTATAAFGARDSGEFRRAPAPPPLPPAEPL 443
+P P SP + P P ++ +A G+ AP L
Sbjct: 98 KNTSPGP----VSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGA-- 151
Query: 444 AKEKPGTPPGPPPPDTNSMELGGRPTFGWS-PEPCDSPGTPTLESSPAGPEKPHDSLDSR 502
++ G PG P P G P P P PT E P S+ S
Sbjct: 152 RRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPT--------EGPRKSVSSA 203
Query: 503 IEMLLKEQRTKLLFLREPDSDTELQMEGS-PISSSSSQLSPLAPFGTNSQPGFRGPTPPS 561
E E R P + LQ S +SSS++ LS A G +++ R P PS
Sbjct: 204 SEHSTTEPSPAAR--RRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPS 261
Query: 562 SRPSSTGLEDISPTPLPDSDEDEELDLG-LGPRPPPEPGPPDPAGLLSQTAEVALDLVGD 620
+P GL+ + P + +D LG L P P P P S +A +L +
Sbjct: 262 -QPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPP---SPSAPPSLQTLP- 316
Query: 621 RTPTSEKMDEGQQSSGED-MEISDDEMPSAPITSADCPKPMV----------------VT 663
+P + + S G ++ + +PS P++ P P +
Sbjct: 317 -SPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPAS 375
Query: 664 PGAAAVAAPSVLAPTL-------------PLPP------PPGFPPLPPPPPPP------- 697
P + +A PS AP P PP PP PP+ P PP
Sbjct: 376 PPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSL 435
Query: 698 -------PPQPGFPMPPPL-----PPPPPPPPPAHPAVTVPPPPLPAPPGVPPPPILPPL 745
PP P P PP+ PPP PPP A P + + PP APP + PP+
Sbjct: 436 AAPPLQVPPSP--PASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPL--QA 491
Query: 746 PPFPPGLFPVMQVDMSHVLGGQWGGMPMSFQMQTQVLSRLMTGQGACPYPPFMAAAAAAA 805
P PP FP GQ P + + + + P + A
Sbjct: 492 LPSPPASFP-----------GQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPA 540
Query: 806 SAGLQFVNLPPYRGPFSLSNSGPGRGQHWPPLPKFDPSVPP 846
S LQ PP GP S SGP P P PS P
Sbjct: 541 SPTLQAPRRPPTPGP-DTSVSGPRLTLALAPGPPPPPSRSP 580
Score = 87.0 bits (214), Expect = 2e-16
Identities = 127/531 (23%), Positives = 181/531 (34%), Gaps = 88/531 (16%)
Query: 216 ETLQLSDALKRLKDGGLSAGCGSGSSSVTPNSGGTPFSQDTAYSSCRLDTPNSYGQGTPL 275
ET+ A + K LSAG +S TP + ++ + + + P P
Sbjct: 131 ETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPR 190
Query: 276 TPRLGT--PFSQDSSYSSRQPTPSYLFSQDPAVTFKARRHESKFTDAYNRRHEHHYVHNS 333
P G S S +S+ +P+P+ ARR S R ++
Sbjct: 191 PPTEGPRKSVSSASEHSTTEPSPA------------ARRRPSA-GGGLQRPASRSLSSSA 237
Query: 334 PAVTAVAGATAAFRGSSDLPFGAVGGTGGSSGPPFKAQPQDSATFAH---TPPPAQATPA 390
+++ A + + RG+ P P + +P+ TPP A PA
Sbjct: 238 TPLSSPARSGPSARGTPRAP-----------AHPSQPKPKGLQALRPPQVTPPRKDAAPA 286
Query: 391 PGFKSAFSPYQTPVAHFPPPPEEPTATAAFGARDSGEFRRAPAPPPLPPAEPLAKEKPGT 450
G S+ SP TP PP P P + + P+PP PP++ T
Sbjct: 287 LGPLSS-SPLATPSPSAPPSPSAPPS-----------LQTLPSPPATPPSQAT------T 328
Query: 451 PPGPPPPDTNSMELGGRPTFGWSPEPCDSP---GTPTLESSPAGPEKPHDSLDSRIEMLL 507
G P L P + P +P P L++ P+ P P S
Sbjct: 329 SLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSP-------- 380
Query: 508 KEQRTKLLFLREPDSDTELQMEGSPISSSSSQLSPL-APFGTNSQPGFR-GPTPPSSRPS 565
L P + L + S P+ APF + P TPPS P
Sbjct: 381 -------LATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPP 433
Query: 566 STGLEDISPTPLPDSDEDEELDLGLGPRPPPEPGPPDPAGLLSQTAEVALDLVGDRTPTS 625
S + P P + + PPP+ PP A L TP
Sbjct: 434 SLAAPPLQVPPSPPASPP----MSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPL 489
Query: 626 EKMDEGQQSSGEDMEISDDEMPSAPITSADCPKPMVVTPGAAAVAAPSVLAPTLPLPP-P 684
+ + S + P +P SA P + TP A P + AP L +PP P
Sbjct: 490 QALPSPPASF-------PGQAPFSP--SASLPMSPLATPPPQA--PPVLAAPLLQVPPSP 538
Query: 685 PGFPPLPPPPPPPPPQPGFPMPPP-----LPPPPPPPPPAHPAVTVPPPPL 730
P P L P PP P P + P L P PPPPP P+ T+ P L
Sbjct: 539 PASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDL 589
Score = 80.9 bits (198), Expect = 1e-14
Identities = 135/518 (26%), Positives = 178/518 (34%), Gaps = 121/518 (23%)
Query: 1199 APEERPSMLDEPPLPVGVEEPADSRE----PPEEPG----------LSQEGAMLLSPEPP 1244
AP P+ PP E ++ P PG L Q+G + + E
Sbjct: 74 APRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETV 133
Query: 1245 AK----EVEARPPLSP--ERAPEHDLEVEPEPPMM-------LPLPLQPPLPPPRPPRPP 1291
A+ E R LS R P P M + L P P R PRPP
Sbjct: 134 ARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSAR-PRPP 192
Query: 1292 SPPPEPETTDAS-HPSVPPEPLAEDHPPHTPGLCGSLAKSQSTETVPATPGGEPPLSGGS 1350
+ P + AS H + P P A P GL ++S S+ ATP P SG S
Sbjct: 193 TEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSS---ATPLSSPARSGPS 249
Query: 1351 SGLSLSSPQVPGSP------------FSYPAPSPSLSSGGLPRTPGRDFSFTPTFS---E 1395
+ + +P P P + P + + G L +P TP+ S
Sbjct: 250 ARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSP----LATPSPSAPPS 305
Query: 1396 PSGPLLLPVCPLPTGR-RDERSGPLASPVLLETGLPLP----LPLPLPLPLALPAVLRAQ 1450
PS P L P P + + L SP L T LP PL P P A PA+
Sbjct: 306 PSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPP 365
Query: 1451 ARAPTPLPP----------------------LLPAPLASCPPPMKRKPGRPRRSPPSMLS 1488
+AP P PP LL AP + P P + P P SPP S
Sbjct: 366 LQAP-PSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPS 424
Query: 1489 LDGPLVRPPAGAALGRELLLLPGQPQT-PVFPSTHDPRTVTLDFRNAGIPAPPPPL---- 1543
P PP+ AA L + P P + P+ PS P P PPPL
Sbjct: 425 ATPPSQAPPSLAA--PPLQVPPSPPASPPMSPSATPP------------PQAPPPLAAPP 470
Query: 1544 ------PPQPPPP---------PPPPPVEPTKLPFKELDNQWPSEAIPPGPRGRDEVTEE 1588
PPQ PP P PP P + PF + S P P+ +
Sbjct: 471 LQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAP 530
Query: 1589 YMELAKS--RGPWRRPPKKRHEDLVPPAGSPELSPPQP 1624
+++ S P + P++ PP P+ S P
Sbjct: 531 LLQVPPSPPASPTLQAPRR------PPTPGPDTSVSGP 562
Score = 69.3 bits (168), Expect = 3e-11
Identities = 106/422 (25%), Positives = 140/422 (33%), Gaps = 90/422 (21%)
Query: 1275 PLPLQPPLPPPRPPRPPSPPPEPETTDA-----SHPSVPPEPLAEDHPPHTPGLCGSLAK 1329
P P L PRPP P PPP P T A + +V +PLAE G G
Sbjct: 17 PAARAPGLLTPRPPGSPRPPP-PVTPAALRVLGAAGAVGRKPLAE-----RAGGIGGATI 70
Query: 1330 SQSTETVPATPGGEPPLSGGSSGLSLSSPQVPGSPFSYPAPSPSLSSGGLPRTPGRDFSF 1389
+S T PP SG + PG P S P + + G G S
Sbjct: 71 PESAPRAGPTRTSRPPASGRGERAPPAKNTSPG-PVSSPGRASGTTRPGPLGQKGLRISA 129
Query: 1390 TPTFSEPSGPLLLPVCPLPTGRRDERSGP---LASPVL--------LETGLPLPLPLPLP 1438
T + L G R + SGP SP + E GLP P P P
Sbjct: 130 EETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARP 189
Query: 1439 LP---------------------------------LALPAVLRAQARAPTPL-PPLLPAP 1464
P L PA R+ + + TPL P P
Sbjct: 190 RPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPA-SRSLSSSATPLSSPARSGP 248
Query: 1465 LASCPPPMKRKPGRPRRSPPSMLSLDGPLVRPP---AGAALG------------------ 1503
A P P +P+ P + +L P V PP A ALG
Sbjct: 249 SARGTPRAPAHPSQPK--PKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSP 306
Query: 1504 ---RELLLLPGQPQTPVFPSTHDPRTVTLDFRNAGIPAPP-PPLPPQPPPPPPPPPVEPT 1559
L LP P TP +T + TL ++ +P+PP PL PP PP + P
Sbjct: 307 SAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPL 366
Query: 1560 KLPFKELDNQWPSEAIPPGPRGRDEVTEEYMELAKSRGPWRRPPKKRHEDLVPPAGSPEL 1619
+ P + S P P+ + + ++ P+ PP + P SP +
Sbjct: 367 QAPPSPPASPPLSPLATPSPQAPNALAVHLLQ-----APFSPPPSPPVQAPFSPPASPPV 421
Query: 1620 SP 1621
SP
Sbjct: 422 SP 423
Score = 53.9 bits (128), Expect = 1e-06
Identities = 66/247 (26%), Positives = 92/247 (37%), Gaps = 30/247 (12%)
Query: 364 SGPPFK-AQPQDSATFAHTPPPAQATPAPGFKSAFSPYQTPVAHFP------PPPEEPTA 416
+ PP + A+P A A PP QA P+P +P A P PPP+ P
Sbjct: 467 AAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPV 526
Query: 417 TAAFGARDSGEFRRAPAPPPLPPAEPLAKEKPGTPPGPPPPDTNSMELGGRPTFGWSPEP 476
AA PP PPA P + P PP P ++ G R T +P P
Sbjct: 527 LAA----------PLLQVPPSPPASPTLQ----APRRPPTPGPDTSVSGPRLTLALAPGP 572
Query: 477 CDSPGTPTLESSPAGPEKPHDSLDSRI---EMLLKEQRTKLLFLREPDSDTELQMEGSPI 533
P + + S+ +GP+ S + E+ + + P D EL +
Sbjct: 573 -PPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAEL----AAC 627
Query: 534 SSSSSQLSPLAPFGTNSQPGFRGPTPPSSRP-SSTGLEDISPTPLPDSDEDEELDLGLGP 592
++ P P PG P PP++ P S+ GL I T P+S L GP
Sbjct: 628 HPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGP 687
Query: 593 RPPPEPG 599
P G
Sbjct: 688 SPGTSGG 694
Score = 47.0 bits (110), Expect = 2e-04
Identities = 53/200 (26%), Positives = 70/200 (35%), Gaps = 26/200 (13%)
Query: 1197 AVAPEERPSMLDEPPLPVGVEEPAD-SREPPEEPGLSQEGAMLLSPEPPAKEVEARP--- 1252
A P + P L PPL PA + P P S + L +P P A V A P
Sbjct: 474 AKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQ 533
Query: 1253 -PLSPERAPEHDLEVEPEPP----------MMLPLPLQPPLPPPRPPRPPSPPPEPETTD 1301
P SP +P P P + L L PP PP R P P+
Sbjct: 534 VPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHS 593
Query: 1302 ASHPSVPPEPLAEDHPPHTPGLCGSLAKSQSTETVPA--TPGGEPPLSGGSSGLSLSSPQ 1359
+S S P E D P ++ PA + G PPL+ +
Sbjct: 594 SSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGA-------- 645
Query: 1360 VPGSPFSYPAPSPSLSSGGL 1379
PG+P +P + S+ GL
Sbjct: 646 -PGAPLPWPPATGPGSADGL 664
Score = 35.0 bits (79), Expect = 0.71
Identities = 31/98 (31%), Positives = 33/98 (33%), Gaps = 13/98 (13%)
Query: 667 AAVAAPSVLAPTLPLPPPPGFPPLPPPPPPPPPQ----PGFPMPPPLPPP---------P 713
AA P+ AP L P PPG P PPP P + G PL P
Sbjct: 12 AAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIP 71
Query: 714 PPPPPAHPAVTVPPPPLPAPPGVPPPPILPPLPPFPPG 751
P A P T PP PP P P PG
Sbjct: 72 ESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPG 109
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 104 bits (259), Expect = 9e-22
Identities = 160/574 (27%), Positives = 201/574 (35%), Gaps = 97/574 (16%)
Query: 230 GGLSAGCGSGSSSVTPNSGGTPFSQDTAYSSCRLDTPNSYGQGTPLTPRLGTPFSQDSSY 289
G LS+ +S P + + + ++ TP S +G P TP TP S
Sbjct: 822 GNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPS-PKGAP-TPSAVTPLSPKGVT 879
Query: 290 SSRQPTPSYLFSQDPAVTFKARRHESKFTDAYNRRHEHHYVHNSPAVTAVAGATAAFRG- 348
+ TP+ P+V E T A + +SP A AT A +G
Sbjct: 880 LPPKETPT------PSVVNLPFPKEGPATPAPKQAPALSMTSSSPKK---ARATPAPKGI 930
Query: 349 -SSDLPFGAVGGTGGSSGPPFKAQPQDSATFAHTPPPAQATPAPGFKSAFSPY--QTPVA 405
+S P GA + P S +A TPP A G + SP TP A
Sbjct: 931 PASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPA 990
Query: 406 HFPPPPEEPTATAAFGARDSGEFRRAPAPPPLPPAEPLAKEKPGTPPGPPPPDTNSMELG 465
PP P+ AT + + P+P P A P K TPP PP
Sbjct: 991 ATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGA-STPPAATPPSPK----- 1044
Query: 466 GRPTFGWSPEPCDSPGTP--TLESSPAGPEKPHDSLDSRIEMLLKEQRTKLLFLREPDSD 523
G P +P P +P TP TL S GP P LK T P +
Sbjct: 1045 GSPAA--TPLPKGAPTTPAATLPSPKGGPATPS----------LKGAPT-------PPAA 1085
Query: 524 TELQMEGSPISSSSS------QLSPLAPFGTNSQPGFRG-PTPPSSRPSST--GLEDISP 574
T +G P + S +P +P G + P +G PT P++ P S GL P
Sbjct: 1086 TPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPP 1145
Query: 575 --TPLPDSDEDEELDLGLGPRPP------PEPGPPDPAGLLSQTAEVALDLVGDRTPTSE 626
P + GL PP P PP P G L+ + TP S
Sbjct: 1146 KGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSP 1205
Query: 627 KMDEGQQSSGEDMEISDDEMPSAPITSADCPKPMVVTPGAAAVAAPSVLAPTLPLP---- 682
K G S P+ P + PK + TP AP+ A T P P
Sbjct: 1206 K--------GGLATPSPKGAPTTPAATPPSPKGGLATPSPKG--APTTPAATPPSPKGGP 1255
Query: 683 --PPPGFPPLPPPPPPP--------PPQPGFPMP----PPLPP------PP---PPPPPA 719
PPP P PP PP PP G P P PP P PP P PP A
Sbjct: 1256 ATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAA 1315
Query: 720 HPAVTVPPPPLPAPPGVP-PPPILPPLPPFPPGL 752
P P P P G P PP + PP P P L
Sbjct: 1316 TPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTL 1349
Score = 102 bits (254), Expect = 4e-21
Identities = 129/448 (28%), Positives = 162/448 (36%), Gaps = 84/448 (18%)
Query: 1210 PPLPVG---VEEPADSREPPEEPGLSQEGAMLLSPEPPAKEVEARPPLSPERAPEHDLEV 1266
PP P G P + PP S +G+ +P P PP + +P+
Sbjct: 993 PPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGAST---PPAATPPSPKGS--- 1046
Query: 1267 EPEPPMMLPLPLQPPLPP----PRP---PRPPSPPPEPETTDASHPS-----VPPEPLAE 1314
P PLP P P P P P PS P A+ PS P P
Sbjct: 1047 ----PAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGA 1102
Query: 1315 DHPPHT--PGLCGSLAKSQSTETVPATPGGEPPLSGGSSGLSLSSPQVPGSPFSYPAPSP 1372
PP P G LA + + P TP PP G L++P G+P + PA +P
Sbjct: 1103 PMPPAATPPSPKGGLA-TPPHKGAPTTPAATPPSPKG----GLATPPPKGAP-TTPAATP 1156
Query: 1373 SLSSGGLPRTPGRDFSFTPTFSEPSGPLLLPVCPLPTGRRDERSGPLASPVLLETGLPLP 1432
GGL P + TP + PS P P P G + P A+P + GL P
Sbjct: 1157 PSPKGGLATPPPKGAPTTPAATPPS-PKGGLATPSPKG---APTTPAATPPSPKGGLATP 1212
Query: 1433 LPLPLP-LPLALPAVLRAQARAPTPL-PPLLPAPLASCP------PPMKRKPGRPRRSPP 1484
P P P A P + P+P P PA P PP K P P +PP
Sbjct: 1213 SPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPP 1272
Query: 1485 SMLSLDGPLVRPPAGAALGRELLLLPGQPQTPVFPSTHDPRTVTLDFRNAGIPAPPPPLP 1544
SL G L PP A ++ P P+ P+T P+ G P PP P
Sbjct: 1273 ---SLKGGLATPPHKGA-PNPAVVTPPSPKGG--PATSPPK---------GAPTPPAATP 1317
Query: 1545 PQP--PPPPPPPPVEPTKLPFKELDNQWPSEAIPPGPRGRDEVTEEYMELAKSRGPWRRP 1602
P P P PPP PT P PP P+G + S+G P
Sbjct: 1318 PSPKGSPGTPPPKGAPT-----------PPAVTPPSPKGTPTLP---ATTPSSKGGPTTP 1363
Query: 1603 PKKRHEDLVPPA------GSPELSPPQP 1624
K E PPA G P ++PP P
Sbjct: 1364 SSK--EGPTPPAATPSHKGGPAMTPPSP 1389
Score = 100 bits (249), Expect = 1e-20
Identities = 138/525 (26%), Positives = 172/525 (32%), Gaps = 125/525 (23%)
Query: 362 GSSGPPFKAQPQDSATFAHTPPPAQATPAP-GFKSAFSPY--QTPVAHFPPPPEEPTATA 418
G + P K P S T + +P A+ATPAP G ++ SP TP A PP P+ AT
Sbjct: 899 GPATPAPKQAPALSMT-SSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATP 957
Query: 419 AFGARDSGEFRRAPAPPPLPPAEPLAKEKPGTPPGPPPPDTNSMELGGRPTFGWSPEPCD 478
+ + AP PP P P +P G P P + P P
Sbjct: 958 SP--------KWAPTPPAATPPSPKGGPATPSPKGAPTPPAAT-----------PPSPKG 998
Query: 479 SPGTPTLESSPAGPE--KPHDSLDSRIEMLLKEQRTKLLFLREPDSDTELQMEGSPISSS 536
P TP+ + +P P P K T P + T +GSP ++
Sbjct: 999 GPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGAST-------PPAATPPSPKGSPAATP 1051
Query: 537 SSQLSPLAPFGT-------NSQPGFRG-PTPPSSRPSSTGLEDISPTPLPDSDEDEELDL 588
+ +P P T + P +G PTPP++ P S +P+P
Sbjct: 1052 LPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPK----------- 1100
Query: 589 GLGPRPPPEPGPPDPAGLLSQTAEVALDLVGDRTPTSEKMDEGQQSSGEDMEISDDEMPS 648
G PP PP P G L+ TP S K G P+
Sbjct: 1101 --GAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPK--------GGLATPPPKGAPT 1150
Query: 649 APITSADCPKPMVVTP---GAAAVAAPSVLAPT--LPLPPPPGFPPLPPPPPPPP----- 698
P + PK + TP GA A + +P L P P G P P PP P
Sbjct: 1151 TPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLA 1210
Query: 699 -PQP-GFPMPPPLPPPPP------PPPPAHPAVTVPPPPLPAPPGVPPPPILPPLPPF-- 748
P P G P P PP P P P P PP P PPP P PP
Sbjct: 1211 TPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAAT 1270
Query: 749 PPGLFPVMQVDMSHVLGGQWGGMPMSFQMQTQVLSRLMTGQGACPYPPFMAAAAAAASAG 808
PP L +G PP A A
Sbjct: 1271 PPSL------------------------------------KGGLATPPHKGAPNPAV--- 1291
Query: 809 LQFVNLP-PYRGPFSLSNSG-PGRGQHWPPLPKFDPSVPPPGYMP 851
V P P GP + G P PP PK P PPP P
Sbjct: 1292 ---VTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAP 1333
Score = 98.6 bits (244), Expect = 5e-20
Identities = 105/416 (25%), Positives = 139/416 (33%), Gaps = 35/416 (8%)
Query: 361 GGSSGPPFKAQPQDSATFAHTPPPAQATP----APGFKSAFSPYQTPVAHFPPPPEEPTA 416
GG + PP K P A +P ATP AP +A P PPP PT
Sbjct: 1115 GGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTT 1174
Query: 417 TAAFGARDSGEF-----RRAPAPPPLPP-------AEPLAKEKPGTPPGPPPPDTNSMEL 464
AA G + AP P P A P K P TP PP +
Sbjct: 1175 PAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLAT 1234
Query: 465 G---GRPTF--GWSPEPCDSPGTPTLESSPAGPEKPHDSLDSRIEMLLKEQRTKLLFLRE 519
G PT P P P TP + +P P SL + + +
Sbjct: 1235 PSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTP 1294
Query: 520 PDSDTELQMEGSPISSSSSQLSPLAPFGTNSQP-GFRGPTPPSSRPSSTGLEDISPTPLP 578
P +G P ++S + +P P T P G G PP P+ + SP P
Sbjct: 1295 PSP------KGGP-ATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTP 1347
Query: 579 DSDEDEELDLGLGPRPPPEPGPPDPAGLLSQTAEVALDLVGDRTPTSEKMDEGQQSSGED 638
G P + GP PA S A+ + + +G +S
Sbjct: 1348 TLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAV 1407
Query: 639 MEISDDEMPSAPITSADCPKPMVVTPGAAAVAAPSVLAPTLPLPPPPGFPPLPPPPPPPP 698
+ +S + P+ P+T + TP + P+V +L P P P P
Sbjct: 1408 IPLSPKKAPATPVT-----REGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSK 1462
Query: 699 PQPGFPMPPPLPPPPPPPPPAHPAVTVPPPPLPAPPGVPPPPILPPLPPFPPGLFP 754
P P P P P PP P A + P PA P P LP + P P P
Sbjct: 1463 GDPTLPAVTP-PSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVP 1517
Score = 97.4 bits (241), Expect = 1e-19
Identities = 126/490 (25%), Positives = 170/490 (34%), Gaps = 87/490 (17%)
Query: 1173 AALAPGAPAVDSLGMEEEVDIETEAVAPEERPS----------------MLDEPPLPVGV 1216
A PG VD G+ + A +P+E P+ L + P P+GV
Sbjct: 742 AGTPPGTKKVD--GISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGV 799
Query: 1217 EEPADSREPPEEPGLSQEGAMLLSPEPPAKEVEARPPLSPERA---PEHDLEVE------ 1267
++ PP + G + P+ P + + P+SP A PE+ L +
Sbjct: 800 SVSPQTKRPPTKKGSA-------GPDTPIGNLSS--PVSPVEASFLPENSLSFQGSKDSP 850
Query: 1268 -----PEPPMMLPLPLQPPLPPPRPPRPPSPPPEPETTDASHPSVPPEPLAEDHPPHTPG 1322
P PP P + P P PP E T + P E A P P
Sbjct: 851 ATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPA 910
Query: 1323 LCGSLAKSQSTETVPATPGGEPPLSGGSSGLSLSSPQVPGSPFSYPAPSPSLSSGGLPRT 1382
L + + + PA P G P +SP G+P + PA +P GG P T
Sbjct: 911 LSMTSSSPKKARATPA-PKGIP-----------ASPSPKGAP-TPPAATPPSPKGG-PAT 956
Query: 1383 PGRDFSFTPTFSEPSGPLLLPVCPLPTGRRDERSGPLASPVLLETGLPLPLPLPLPLPLA 1442
P ++ TP + P P P P P G + P A+P + G P P P P A
Sbjct: 957 PSPKWAPTPPAATPPSPKGGPATPSPKG---APTPPAATPPSPKGGPATPSPKGAPTPPA 1013
Query: 1443 LPAVLRAQARAPTPLPPLLPAPLASCPPPMKRKPGRPRRSPPSMLSLDGPLVRPPAGAAL 1502
+ + A TP P P A+ PP K G P +P P P AA
Sbjct: 1014 VTPPSPKGSPAATPFPKGASTPPAATPPSPK---GSPAATPL-------PKGAPTTPAA- 1062
Query: 1503 GRELLLLPGQPQTPVFPSTHDPRTVTLDFRNAGIPAPPPPLPPQPPPPPPPPPVEPTKLP 1562
L G P TP P T G P P P PP PP P P
Sbjct: 1063 --TLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATP 1120
Query: 1563 FKELDNQWPSEAIPPGPRGRDEVTEEYMELAKSRG----PWRRPPKKRHEDLVPP----A 1614
+ P+ A PP P+G + +G P PP + PP
Sbjct: 1121 PHKGAPTTPA-ATPPSPKGG-------LATPPPKGAPTTPAATPPSPKGGLATPPPKGAP 1172
Query: 1615 GSPELSPPQP 1624
+P +PP P
Sbjct: 1173 TTPAATPPSP 1182
Score = 93.6 bits (231), Expect = 2e-18
Identities = 114/447 (25%), Positives = 146/447 (32%), Gaps = 51/447 (11%)
Query: 334 PAVTAVAGATAAFRGSSDLPFGAVGGTG---GSSGPPFKAQPQDSATFAHTPPP--AQAT 388
PA + GA + P G+ T G+S PP P + A TP P A T
Sbjct: 1000 PATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTT 1059
Query: 389 PAPGFKSAFSPYQTPVAHFPPPPEEPTATAAFGARDSGEFRRAPAPPPLPP-------AE 441
PA S TP P P T + G + + AP PP P A
Sbjct: 1060 PAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLAT 1119
Query: 442 PLAKEKPGTPPGPPPPDTNSMELG---GRPTF--GWSPEPCDSPGTPTLESSPAGPEKPH 496
P K P TP PP + G PT P P TP + +P P
Sbjct: 1120 PPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATP 1179
Query: 497 DSLDSRIEMLLKEQRTKLLFLREPDSDTELQMEGSPISSSSSQLSPLAPFGTNSQPGFRG 556
S L P +G+P + +++ SP T S G
Sbjct: 1180 PSPKGG--------------LATPSP------KGAPTTPAATPPSPKGGLATPSPKG--A 1217
Query: 557 PTPPSSRPSST--GLEDISPTPLPDSDEDEELDLGLGPRPPPEPGPPDPAGLLSQTAEVA 614
PT P++ P S GL SP P + GP PP G P P + +
Sbjct: 1218 PTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGG 1277
Query: 615 LDLVGDRTPTSEKMDEGQQSSGEDMEISDDEMPSAPITSADCPKPMVVTPGAAAVAAPSV 674
L + + + G P+ P + PK TP P
Sbjct: 1278 LATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPA 1337
Query: 675 LAPTLPLPPPPGFPPLPPPPPPPPPQPGFPMPP--PLPPPPPPPPPAHPAVTVPP----P 728
+ P P P G P LP P P P P PP P PA+T P P
Sbjct: 1338 VTP----PSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGP 1393
Query: 729 PLPAPPGVPPPPILPPLPPFPPGLFPV 755
+P+P G P P + PL P PV
Sbjct: 1394 AIPSPKGDPTSPAVIPLSPKKAPATPV 1420
Score = 89.7 bits (221), Expect = 2e-17
Identities = 130/477 (27%), Positives = 164/477 (34%), Gaps = 70/477 (14%)
Query: 1209 EPPLPVGVEEPADSREPPEEPGLSQEGAMLLSPEPPAKEVEARPPLSPERAPEHDL-EVE 1267
E P P V P +E P P Q A+ ++ P K AR +P+ P +
Sbjct: 884 ETPTPSVVNLPFP-KEGPATPAPKQAPALSMTSSSPKK---ARATPAPKGIPASPSPKGA 939
Query: 1268 PEPPMMLPLPLQPPLPPPRPPRPPSPPPEPETTDASHPSVP-----PEPLAEDHP----- 1317
P PP P + P P P+PP + P+ P P P A P
Sbjct: 940 PTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGG 999
Query: 1318 PHTPGLCGSLAKSQSTETVP-ATPGGEPPLSGGSSGLSLSSPQVPGSPFSYPAP--SPSL 1374
P TP G+ T P +P P G S+ + + P GSP + P P +P+
Sbjct: 1000 PATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTT 1059
Query: 1375 ------SSGGLPRTPGRDFSFTPTFSEPSGPLLLPVCPLPTGRRDERSGPLASPVLLETG 1428
S G P TP + TP + P P P P P G P A+P + G
Sbjct: 1060 PAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKG---APMPPAATPPSPKGG 1116
Query: 1429 LPLPLPLPLP-LPLALPAVLRAQARAPTPL-PPLLPAPLASCP------PPMKRKPGRPR 1480
L P P P A P + P P P PA P PP K P P
Sbjct: 1117 LATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPA 1176
Query: 1481 RSPPSM---LSLDGPLVRPPAGAAL------GRELLLLPGQPQTPVFPSTHDPRTVTLDF 1531
+PPS L+ P P AA G G P TP + P+
Sbjct: 1177 ATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPA-ATPPSPKGGLATP 1235
Query: 1532 RNAGIPAPPPPLPPQP------PPP---PPPPPVEPTKL-------PFKELDNQWPSEAI 1575
G P P PP P PPP P PP P L P K N P+
Sbjct: 1236 SPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPN--PAVVT 1293
Query: 1576 PPGPRGRDEVTEEYMELAKSRGPWRRPPK-KRHEDLVPPAGS---PELSPPQPLFRP 1628
PP P+G + P PP K PP G+ P ++PP P P
Sbjct: 1294 PPSPKGGPATSP---PKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTP 1347
Score = 87.4 bits (215), Expect = 1e-16
Identities = 123/441 (27%), Positives = 155/441 (35%), Gaps = 84/441 (19%)
Query: 361 GGSSGPPFKAQPQDSATFAHTPPPAQATPAPGFKSAFSPYQTPVAHFPP--------PPE 412
GG + P K P A +P ATP P K A TP A PP PP
Sbjct: 1230 GGLATPSPKGAPTTPAATPPSPKGGPATPPP--KGA----PTPPAATPPSLKGGLATPPH 1283
Query: 413 EPTATAAFGARDSGEFRRAPAPP---PLPPAE--PLAKEKPGTPP---GPPPPDTNSMEL 464
+ A S + A +PP P PPA P K PGTPP P PP
Sbjct: 1284 KGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSP 1343
Query: 465 GGRPTFGWSPEPCDSPGTPTLESSPAGPEKPHDSLDSRIEMLLKEQRTKLLFLREPDSDT 524
G PT + S G PT SS GP P + + + K R P +
Sbjct: 1344 KGTPTLPATTP--SSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPK----RGPAIPS 1397
Query: 525 ELQMEGSPISSSSSQLSPL-APFGTNSQPGFRGP-----TPPSSRPSSTGLEDISPTP-- 576
+G P S + LSP AP ++ G P TPP+ P S + P
Sbjct: 1398 P---KGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKG 1454
Query: 577 ---LPDSDEDEELDLGLGPRPPPEPGPPDPAGLLSQTAEVALDLVGDRTPTSEKMDEGQQ 633
P S D L P P P P Q A + TP G
Sbjct: 1455 GPATPSSKGDPTLPAVTPPSPKEPPAP-------KQVATSSSPKKAPATPAPM----GAP 1503
Query: 634 SSGEDMEISDDEMPSAPITSAD--CPKPMVVTPGAAAVAAP--SVLAPTLPLPPPPGFPP 689
+ + S E+P+ P + D P +++ A AP +++ P + +P P P
Sbjct: 1504 TLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPA 1563
Query: 690 LP----------------PPPPPPPPQPGFPMPPPL--PP----PPPPPPPAHPAVTVPP 727
+P PP P G P P L PP P P P PAVT P
Sbjct: 1564 IPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPS 1623
Query: 728 ----PPLPAPPGVP-PPPILP 743
P PAP G P PP+ P
Sbjct: 1624 PEKGPATPAPKGTPTSPPVTP 1644
Score = 79.3 bits (194), Expect = 3e-14
Identities = 122/466 (26%), Positives = 171/466 (36%), Gaps = 73/466 (15%)
Query: 1210 PPLPVG---VEEPADSREPPEEPGLSQEGAMLLSPEPPAKEVEARPPLSPERAPEHDLEV 1266
PP P G P + PP S +G + P A P SP+ P
Sbjct: 1248 PPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPA----- 1302
Query: 1267 EPEPPMMLPLPLQPPLPPPRPPR--PPSPPPEPETTDASHPSV-PPEPLAEDHPPHTPGL 1323
PP P P P P P+ P +PPP+ T P+V PP P P T
Sbjct: 1303 -TSPPKGAPTP---PAATPPSPKGSPGTPPPKGAPTP---PAVTPPSPKGTPTLPATTPS 1355
Query: 1324 CGSLAKSQSTETVPATPGGEPPLSGGSS--------GLSLSSPQVPGSPFSYPAPSPSLS 1375
+ S++ P P P GG + G ++ SP+ G P S PA P LS
Sbjct: 1356 SKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPK--GDPTS-PAVIP-LS 1411
Query: 1376 SGGLPRTP-GRDFSFTPTFSEPSGPLLLPV----CPLPTGRRDERSGPLA--SPVLLETG 1428
P TP R+ + TP+ + + P + PV P + + + P + P L
Sbjct: 1412 PKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVT 1471
Query: 1429 LPLPLPLPLPLPLALPAVLRAQARAPTPL-PPLLPAPLASCP------PPMKRKPGRP-- 1479
P P P P +A + + P P+ P LPA + S P P +R P P
Sbjct: 1472 PPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTA 1531
Query: 1480 ---RRSPPSMLSLDGPLVRPPAGAALGRELLLLPGQPQTPVFPSTHD---PRTVTLDFRN 1533
+ P+ L+ L+ P ++ +P + P PS+ + P VT
Sbjct: 1532 TLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVT-PSTY 1590
Query: 1534 AGIPAP-----PP----PLPPQPPPPPPPPPVEPTKLPFKELDNQWPSEAIPPGPRGRDE 1584
G P+P PP P P + P PP P P K P P+ +D
Sbjct: 1591 KGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDS 1650
Query: 1585 VTEEYMELAK--------SRG-PWRRPPKKRHEDLVPPAGSPELSP 1621
T K S+G P ++ P E LV PA PE +P
Sbjct: 1651 PTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPA--PESTP 1694
Score = 77.8 bits (190), Expect = 1e-13
Identities = 109/423 (25%), Positives = 144/423 (34%), Gaps = 79/423 (18%)
Query: 369 KAQPQDSATFAHTPPPAQATPAPGFKSAFSPYQTPVAHFPP--PPEEPTATAAFGARDSG 426
K+ P S A TPP + SA +P VA P P E+ A+A ++ +
Sbjct: 732 KSVPSPSLPPAGTPPGTKKVDGISHTSALAP----VASSPKECPTEDSGASATASSKGTL 787
Query: 427 EFRRAPAPPPLPPAEPLAKEKPGTPPGPPPPDT-------------------NSMELGGR 467
+ A +P PL + ++P T G PDT NS+ G
Sbjct: 788 TYL-ADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGS 846
Query: 468 ---PTFGWSPEPCDSPGTPTLES----SPAGPEKPHDSLDSRIEMLLKEQRTKLLFLRE- 519
P SP P G PT + SP G P + L F +E
Sbjct: 847 KDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPT-------PSVVNLPFPKEG 899
Query: 520 PDSDTELQMEGSPISSSSSQLSPL--APFGTNSQPGFRG-PTPPSSRPSSTGLEDISPTP 576
P + Q ++SSS + + AP G + P +G PTPP++ P S +P+P
Sbjct: 900 PATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSP 959
Query: 577 LPDSDEDEELDLGLGPRPPPEPGPPDPAGLLSQTAEVALDLVGDRTPTSEKMDEGQQSSG 636
PP PP P G + + TP S K G
Sbjct: 960 K-------------WAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPK--------G 998
Query: 637 EDMEISDDEMPSAPITSADCPKPM-VVTPGAAAVAAPSVLAPTLPLPPPPGFPPLPPPPP 695
S P+ P + PK TP + P P P P G P P P
Sbjct: 999 GPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATP----PSPKGSPAATPLPK 1054
Query: 696 PPPPQPGFPMPPPLPPP-------PPPPPPAHPAVTVPPPPLPAPPGVPPPPILPPLPPF 748
P P +P P P P PP A P P P+P G P PP PP
Sbjct: 1055 GAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPP--AATPPS 1112
Query: 749 PPG 751
P G
Sbjct: 1113 PKG 1115
Score = 71.6 bits (174), Expect = 7e-12
Identities = 113/466 (24%), Positives = 151/466 (32%), Gaps = 86/466 (18%)
Query: 411 PEEPTATAAFGARDSGEFRRAP-APPPLPPAEPLAKEKPGTPPGPPPPDTNSMELGGRPT 469
P PTA+ S + AP A L P P + P PP PP T ++ G T
Sbjct: 699 PLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVD-GISHT 757
Query: 470 FGWSPEPCDSPGTPTLESSPAGPEKPHDSLDSRIEMLLKEQRTKLLFLREPDSDTELQME 529
+P PT +S + +L T L
Sbjct: 758 SALAPVASSPKECPTEDSGASATASSKGTL------------------------TYLADS 793
Query: 530 GSPISSSSSQLSPLAPFGTNSQPGFRGPTPPSSRPSSTGLEDISPTPLPDSDEDEELDLG 589
SP+ S S + P ++ G GP P SS + + + LP++ +
Sbjct: 794 PSPLGVSVSPQTKRPP----TKKGSAGPDTPIGNLSSP-VSPVEASFLPENSLSFQGSKD 848
Query: 590 LGPRPPPEPGPPDPAGLLSQTAEVALDLVGDRTPTSEKMDEGQQSSGEDMEISDDEMPSA 649
P P PP P G + +A TP S K + + E P+
Sbjct: 849 -SPATTHSPTPPSPKGAPTPSAV---------TPLSPK----------GVTLPPKETPTP 888
Query: 650 PITSADCPKPMVVTPGAAAVAAPSVLAPT----LPLPPPPGFPPLPPP---PPPPPPQPG 702
+ + PK TP A S+ + + P P G P P P P PP P
Sbjct: 889 SVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPP 948
Query: 703 FPMPPPLPPPP---PPPPPAHPAVTVPPPPLPAPPGVP-PPPILPPLP------------ 746
P P P P P PP A P P P+P G P PP PP P
Sbjct: 949 SPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGA 1008
Query: 747 PFPPGLFPVMQVDMSHVLGGQWGGMPMSFQMQTQVLSRLMTGQGACPYPPFMAAAAAAAS 806
P PP + P G P T + + +G+ P A +
Sbjct: 1009 PTPPAVTPPSP-------KGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPA 1061
Query: 807 AGLQFVNLPPYRGPFSLSNSG-PGRGQHWPPLPKFDPSVPPPGYMP 851
A L P GP + S G P PP PK P+ P P P
Sbjct: 1062 ATLP----SPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAP 1103
Score = 69.3 bits (168), Expect = 3e-11
Identities = 107/388 (27%), Positives = 134/388 (34%), Gaps = 50/388 (12%)
Query: 1234 EGAMLLSPEP-PAKEVEARP-PLSPER------APEHDLEVEPEPPMMLPLPLQPPLPPP 1285
EG + L+P+ P KE PL P AP P ++L + +P P
Sbjct: 678 EGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSP 737
Query: 1286 RPPRPPSPPPEPETTDASHPSV-----------PPEPLAEDHPPHTPGLCGSLAKSQSTE 1334
P +PP + SH S P E + G LA S S
Sbjct: 738 SLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPL 797
Query: 1335 TVPATPGGE-PPLSGGSSGL-----SLSSPQVPGSPFSYPAPSPSLSSGGLPRTPGRDFS 1388
V +P + PP GS+G +LSSP P + P SLS G +P S
Sbjct: 798 GVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVE--ASFLPENSLSFQGSKDSPATTHS 855
Query: 1389 FTPTFSEPSGPLLLPVCPLPTGRRDERSGPLASPVLLETGLPLPLPLP-LPLPLALPAVL 1447
PT P G P P + P +P LP P P P P PA+
Sbjct: 856 --PTPPSPKG-APTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALS 912
Query: 1448 RA-----QARAPTPLP---PLLPAPLASCPPPMKRKPGRPRRSPPSMLSLDGPLVRPPAG 1499
+ARA TP P P P+P + PP P P+ P + P PPA
Sbjct: 913 MTSSSPKKARA-TPAPKGIPASPSPKGAPTPPAATPPS-PKGGPATPSPKWAP--TPPAA 968
Query: 1500 AALGRELLLLPGQPQTPVFPSTHDPRTVTLDFRNAGIPAPPPPLPPQPPP-PPPPPPVEP 1558
+ G P TP P T G P P P PP PP P P
Sbjct: 969 TPPSPK-----GGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSP 1023
Query: 1559 TKLPFKELDNQWPSEAIPPGPRGRDEVT 1586
PF + P A PP P+G T
Sbjct: 1024 AATPFPK-GASTPPAATPPSPKGSPAAT 1050
Score = 69.3 bits (168), Expect = 3e-11
Identities = 115/441 (26%), Positives = 154/441 (34%), Gaps = 104/441 (23%)
Query: 340 AGATAAFRGSSDLPFGAVGGTGGSSGPPFKAQPQD----SATFAHTPPPAQATPA----P 391
A AT A G+ LP AV + P + +D +AT PA P P
Sbjct: 1493 APATPAPMGAPTLP--AVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIP 1550
Query: 392 GFKSAFSPYQTPVAHFPPPPEEPTATAAFGARDS------GEFRRAPAPPPL--PPA--E 441
+ SP +TP P P+E AT + S ++ AP+P L PPA
Sbjct: 1551 PAMTVPSPKKTPAI---PTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTS 1607
Query: 442 PLAKEKPGTPPGPPPPDTNSMELGGRPTFGWSPEPCDSPGTPTLESSPAGPEKPHDSLDS 501
P KE P TPP PP SPE P TP + +P P
Sbjct: 1608 PSPKEAP-TPPAVTPP---------------SPEK--GPATPAPKGTPTSP--------- 1640
Query: 502 RIEMLLKEQRTKLLFLREPDSDTELQMEGSPISSSSSQLSPLAPFGTNSQPGFRGPTPPS 561
P++ SS + SP +P + G P
Sbjct: 1641 ------------------------------PVTPSSLKDSPTSPASVTCKMGATVPQASK 1670
Query: 562 SRPSS---TGLEDISPTPLPDSDEDEELDLGLGPR--------PPPEPGPPDPAGLLSQT 610
P+ T L+++ P P+S GP+ PP P P G
Sbjct: 1671 GLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPL 1730
Query: 611 AEVA----LDLVGDRTPTSEKMDEGQQSSGEDMEISDDEMPSAPITSADCPKPMVVTPGA 666
+ VA L + D + T++ D G + S P+T+A K + A
Sbjct: 1731 STVAPAPLLPVQKDSSKTAKGKDASHSPKGP--LAPPESKASTPLTAAAFEKVLPKPESA 1788
Query: 667 AAVAAPSVLAPTLPLPPPPGFPPLPPPPPPPPPQPGFPMPPPLPPPPPPPPPAHPAVTVP 726
+ AAPS +LPL P P P LPP P PG L P P PA +P
Sbjct: 1789 SVSAAPSP-PVSLPLAPSP-VPTLPPKQQFLPSSPGL----VLESPSKPLAPADEDELLP 1842
Query: 727 -PPPLPAPPGVPPPPILPPLP 746
PP P GVP +L +P
Sbjct: 1843 LIPPEPISGGVPFQSVLVNMP 1863
Score = 63.5 bits (153), Expect = 2e-09
Identities = 119/504 (23%), Positives = 170/504 (33%), Gaps = 99/504 (19%)
Query: 1199 APEERPSMLDEPPLPVGVEEPADSREPPEEPGL--SQEGAMLLSPEPPAKEVEARP---- 1252
+P+ P++ P G S+E P P S +G ++P P K A P
Sbjct: 1342 SPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSP-KRGPAIPSPKG 1400
Query: 1253 --------PLSPERAPEHDLEVEPE---------PPMMLPLPLQ---------------- 1279
PLSP++AP + E PP + P+ L+
Sbjct: 1401 DPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPS 1460
Query: 1280 ----PPLPPPRPPRPPSPPPEPETTDASHPSVPPEPLAEDHPPHTPGLCGSLAKSQSTET 1335
P LP PP P PP + +S P P A P P + S S +
Sbjct: 1461 SKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPS-----SPKE 1515
Query: 1336 VPATPGG-EPPLSGGSSGLSLSSPQ--VPGSPFSYPA---PSPSLSSGGLPRTPGRDFSF 1389
VPATP P++ ++ LS +P P PA PSP + +P TP ++
Sbjct: 1516 VPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPK-KTPAIP-TP-KEAPA 1572
Query: 1390 TPTFSEPSGPLLLPVCPLPTGRRDERSGPLASPVLLETGLPLPLPLPLPLPLALPAVLRA 1449
TP+ E S P P T + P +L+ + P P P P A+
Sbjct: 1573 TPSSKEASSP---PAVTPST----YKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPE 1625
Query: 1450 QARAPTPLPPLLPAPLASCPPPMKRKPGRPRRSPPSMLSLDGPLVRPPAGAALG------ 1503
+ A TP P P P +K P SP S+ G V P A L
Sbjct: 1626 KGPA-TPAPKGTPTSPPVTPSSLKDSP----TSPASVTCKMGATV-PQASKGLPAKKGPT 1679
Query: 1504 --RELLLLPGQPQTPVF--PSTHDPRTVTLDFRNAGIPAPPPPLPPQPP---------PP 1550
+E+L+ P TP+ P+ P+T A PP+ P P
Sbjct: 1680 ALKEVLVAPAPESTPIITAPTRKGPQTKKSS-------ATSPPICPDPSAKNGSKGPLST 1732
Query: 1551 PPPPPVEPTKLPFKELDNQWPSEAIPPGPRGRDEVTEEYMELAKSRGPWRRPPKKRHEDL 1610
P P+ P + + + P GP E A + P+
Sbjct: 1733 VAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSA 1792
Query: 1611 V--PPAGSPELSPPQPLFRPRSEF 1632
PP P P P P+ +F
Sbjct: 1793 APSPPVSLPLAPSPVPTLPPKQQF 1816
Score = 60.5 bits (145), Expect = 2e-08
Identities = 108/448 (24%), Positives = 160/448 (35%), Gaps = 85/448 (18%)
Query: 1157 SMASAGPEDFEQDGEEAALAPGAPAVDSLGMEEEVDIETEAVAPEERPSMLDEPPLPVGV 1216
S GP G+ A P+ ++V + P+ + P LP +
Sbjct: 1450 SAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVI 1509
Query: 1217 EEPADSREPPEEPGLSQEG----AMLLSPEPPA----KEVEARPPLS------------P 1256
P+ +E P P ++ A LLS + PA KE P ++ P
Sbjct: 1510 --PSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTP 1567
Query: 1257 ERAPEHDLEVEPE-PPMMLP-----------LPLQPPLPPPRPPRPPSPPPEPETTDASH 1304
+ AP E PP + P L + P + P P P+PP +
Sbjct: 1568 KEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKG 1627
Query: 1305 PSVPPEPLAEDHPPHTPGLCGSLAKSQST------ETVPATPGGEPPLSGGSSGLSLSSP 1358
P+ P PP TP S ++ TVP G P G ++ L
Sbjct: 1628 PATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTA---LKEV 1684
Query: 1359 QVPGSPFSYPAPSPSLSSGGLPRTPGRDFSFTPTFSEPS------GPL--LLPVCPLPTG 1410
V +P S P + G P+T + P +PS GPL + P LP
Sbjct: 1685 LVAPAPESTPIITAPTRKG--PQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQ 1742
Query: 1411 RRDERS-----------GPLASPVLLETGLPLPLPLPL---PLPLALPAVLRAQARAPTP 1456
+ ++ GPLA P E+ PL LP A + A P
Sbjct: 1743 KDSSKTAKGKDASHSPKGPLAPP---ESKASTPLTAAAFEKVLPKPESASVSAAPSPPVS 1799
Query: 1457 LPPLLPAPLASCPPPMKRKPGRPRRSPPSMLSLDGPLVRPPAGAALGRELLLLPGQPQTP 1516
LP L P+P+ + PP + P P L L+ P +P A A L L+P +P +
Sbjct: 1800 LP-LAPSPVPTLPPKQQFLPSSPG------LVLESP-SKPLAPADEDELLPLIPPEPISG 1851
Query: 1517 VFPSTHDPRTVTLDF---RNAGIPAPPP 1541
P ++V ++ ++AGIP P P
Sbjct: 1852 GVPF----QSVLVNMPTPKSAGIPVPTP 1875
Score = 60.1 bits (144), Expect = 2e-08
Identities = 114/481 (23%), Positives = 164/481 (34%), Gaps = 57/481 (11%)
Query: 361 GGSSGPPFKAQPQDSATFAHTPPPAQATPAPG-FKSAFSPYQTPVAHFPPPPEEPTATAA 419
GG + P K P A TPP + PAP ++ SP + P P P PT A
Sbjct: 1454 GGPATPSSKGDPTLPAV---TPPSPKEPPAPKQVATSSSPKKAPAT--PAPMGAPTLPAV 1508
Query: 420 FGARDSGEFRRAPAPPPLPPAEPLAKEKPGTPPGP----PPPDTNSMELGGRPTFGWSPE 475
P+ P PA P ++ P P P T + + P P
Sbjct: 1509 I-----------PSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPS 1557
Query: 476 PCDSPGTPTLESSPAGPEKPHDSLDSRIEMLLKEQRTKLLFLREPDSDTELQMEGSPISS 535
P +P PT + +PA P S + T + P S EL + + ++S
Sbjct: 1558 PKKTPAIPTPKEAPATPSSKEASSPPAV--------TPSTYKGAP-SPKELLIPPA-VTS 1607
Query: 536 SSSQLSPLAPFGTNSQPGFRGPTPPSSRPSSTGLEDISPTPLPDSDEDE-ELDLGLGPRP 594
S + +P P T P +GP P+ + + T ++P+ L DS + +G
Sbjct: 1608 PSPKEAPTPPAVTPPSPE-KGPATPAPKGTPTS-PPVTPSSLKDSPTSPASVTCKMGATV 1665
Query: 595 PPE----PGPPDPAGLLSQTAEVALDLVGDRTPTSEKMDEGQQSSGEDMEISDDEMPSAP 650
P P P L A + T + K + ++SS I D PSA
Sbjct: 1666 PQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPD--PSAK 1723
Query: 651 ITSADCPKPMVVTPGAAAVAAPSVLAPTLPLPPPPGFPPLPPPPPPPPPQPGFPMPPPLP 710
S + P S A P P PP P LP
Sbjct: 1724 NGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLP 1783
Query: 711 PPPPPPPPAHPAVTVPPPPLPAPPGVPPPPILPPLPPFPPGLFPVMQVDMSHVLGGQWGG 770
P A P+ PP LP P P P LPP F P S L +
Sbjct: 1784 KPESASVSAAPS---PPVSLPLAPS--PVPTLPPKQQFLPS---------SPGLVLESPS 1829
Query: 771 MPMSFQMQTQVLSRLMTG--QGACPYPPFMAAAAAAASAGLQFVNLPPYRGPFSLSNSGP 828
P++ + ++L + G P+ + SAG+ V P + P + +N G
Sbjct: 1830 KPLAPADEDELLPLIPPEPISGGVPFQSVLVNMPTPKSAGIP-VPTPSAKQPVTKNNKGS 1888
Query: 829 G 829
G
Sbjct: 1889 G 1889
Score = 47.8 bits (112), Expect = 1e-04
Identities = 175/731 (23%), Positives = 233/731 (31%), Gaps = 130/731 (17%)
Query: 199 PQTLPVGELDAVSPIVNETLQLSDALKRLKDGGLS-AGCGSGSSSVTPNSGGTPF---SQ 254
PQT P L SP V +T S + G LS G S ++++ ++ P SQ
Sbjct: 231 PQTTPTTTLAIASPQVKDTTISSVLISPQNPGSLSLKGPVSPPAALSLSTQSLPVVTSSQ 290
Query: 255 DTAYSSCRLDTPNSYGQGTPLTPRLGTPFSQDSSYSSRQPTPSYLFSQDPAVTFKARRHE 314
TA + D P S G+ L P + F S Q PS L DP V + H
Sbjct: 291 KTAGPNTPPDFPISL--GSHLAPLHQSSFG--SVQLLGQTGPSAL--SDPTVKTISVDHS 344
Query: 315 SKFTDAYNRRHEHHYVHNSPAVTAVAGAT-AAF--------RGSSDLPFGAVGGTGG-SS 364
S ++R + P+ V AT AAF +G S + +G +
Sbjct: 345 STGASYPSQR---SVIPPLPSRNEVVPATVAAFPVVAPSVDKGPSTISSITCSPSGSLNV 401
Query: 365 GPPFKAQPQDSATFAHTPPPAQATPAPGFKSAFSPYQTPVA-------HFPPPPEEPTAT 417
F P S +P P S TP+ P AT
Sbjct: 402 ATSFSLSPTTSLILKSSPNATYHYPLVAQMPVSSVGTTPLVVTNPCTIAAAPTTTFEVAT 461
Query: 418 AAFGARDSGEFRR-APAPPPLPPAEPLAKEKPGT--------PPGPPPPDTNSMELGGRP 468
SG P P P+A ++P T P PP PD ++
Sbjct: 462 CVSPPMSSGPISNIEPTSPAALVMAPVAPKEPSTQVATTLRIPVSPPLPDPEDLKNLPSS 521
Query: 469 TFGWSPEPCDSPGTP-TLESSPAGPEKPHDSLDSRIEMLLKEQRTKL-LFLREPDSDTEL 526
P D P +LE +P P ++ + K+ T L L P +
Sbjct: 522 VLVKFPTQKDLQTVPASLEGAPFSP--------AQAGLTTKKDPTVLPLVQAAPKNSPSF 573
Query: 527 QMEGSPISSSSSQLSPLAPFGTNSQPGFRGPTPPSSRPSSTGLEDISPTPLPDSDEDEEL 586
Q S+SSS PL+P T ++ P P SS SP + S +
Sbjct: 574 Q------STSSSPEIPLSPEATLAKKSLGEPLPIGKPASSM----TSPLGVNSSASVIKT 623
Query: 587 DLGLGPRPPPEPGP------------------PDPAGLLSQTAEVALDLVGDRTPTSEKM 628
D G P GP DPAG+ TA+ +P E
Sbjct: 624 DSYAG---PDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEGT 680
Query: 629 DEGQQSSGEDMEISDDEMPSAPITSADCPKPMVVTPGAAAVAAP---SVLAPTLPLPPPP 685
+ E + +P P S +CP V P AP VLAP +P P
Sbjct: 681 VSLAPKNHPVKEGTLTTLPLVPTASENCP----VAPSPQNTCAPLATLVLAPEIPKSVPS 736
Query: 686 GFPPLPPPPPPPPPQ--PGFPMPPPLPPPPPPPP--PAHPA------------VTVPPPP 729
P LPP PP + G L P P P + + P
Sbjct: 737 --PSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSP 794
Query: 730 LPAPPGVPPPPILPPL------PPFPPGLF--PVMQVDMSHVLGGQWGGMPMSFQMQTQV 781
P V P PP P P G PV V+ S + +SFQ
Sbjct: 795 SPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENS-----LSFQGSKD- 848
Query: 782 LSRLMTGQGACPYPPFMAAAAAAASAGLQFVNLPPYRGPF-SLSNSGPGRGQHWPPLPKF 840
S T P P +A + V LPP P S+ N P PK
Sbjct: 849 -SPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNL---------PFPKE 898
Query: 841 DPSVPPPGYMP 851
P+ P P P
Sbjct: 899 GPATPAPKQAP 909
Score = 43.1 bits (100), Expect = 0.003
Identities = 77/335 (22%), Positives = 112/335 (33%), Gaps = 54/335 (16%)
Query: 1229 PGLSQEGAMLLSP---EPPAKEVEARPPLSPERAPEHDLEVEPEPPMMLPLPLQPPLPPP 1285
P + E A +SP P +E P + AP E + L +P+ PPLP P
Sbjct: 453 PTTTFEVATCVSPPMSSGPISNIEPTSPAALVMAPVAPKEPSTQVATTLRIPVSPPLPDP 512
Query: 1286 RPPRPPSPPPEPETTDASHPSVPPEPLAEDHPPHTPGLCGSLAKSQST--ETVPATPGGE 1343
+ + P + + P + + P +P G K T V A P
Sbjct: 513 EDLK--NLPSSVLVKFPTQKDLQTVPASLEGAPFSPAQAGLTTKKDPTVLPLVQAAPKNS 570
Query: 1344 PPLSGGSSGLSLSSPQVPGSPFSYPAPSPSLSSGGLPRTPGRDFS--FTPTFSEPSGPLL 1401
P S SSP++P SP + A S G P G+ S +P S ++
Sbjct: 571 PSFQSTS-----SSPEIPLSPEATLAK----KSLGEPLPIGKPASSMTSPLGVNSSASVI 621
Query: 1402 LPVCPLPTGRRDERSGPLASPVLLETGLPLPLPLPLPLPLALPA-----VLRAQARAPTP 1456
+ D +GP ++ LL++ L P PL A PA + + T
Sbjct: 622 ---------KTDSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTAKGTSTYTTT 672
Query: 1457 LPPLLPAPLASCPPPMKRKPGRPRRSP-PSMLSLDGPLVRPPAGAALGRELLLLPGQPQT 1515
P L ++ P K G P S + P+ P L+L
Sbjct: 673 ASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVL-----A 727
Query: 1516 PVFPSTHDPRTVTLDFRNAGIPAPPPPLPPQPPPP 1550
P P + P P LPP PP
Sbjct: 728 PEIPKS----------------VPSPSLPPAGTPP 746
Score = 42.4 bits (98), Expect = 0.004
Identities = 46/176 (26%), Positives = 60/176 (34%), Gaps = 21/176 (11%)
Query: 591 GPRPPPEPGPPDPAGLLSQTAEVALDLVGDRTPTSEKMDEGQQSSGEDMEISDDEMPSAP 650
GP PP P P P A A T S ++ S + P AP
Sbjct: 42 GPTLPP-PCSPAPQQCPLSAANQASPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAP 100
Query: 651 ITSADCPKPMVVTPGAAAVAAPSVLAPTLPLPPPPGFPPLPPPPPPPPPQPGFPMPPPLP 710
+ P + +P A A+A+P ++APTL P P P Q PP L
Sbjct: 101 TFLPNLIGPPI-SPAALALASP-MIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLL 158
Query: 711 PPPP---------------PPPPAHPAVT---VPPPPLPAPPGVPPPPILPPLPPF 748
PP P P+ P VP +P P G P PP + P+
Sbjct: 159 TSPPSVAVAESGSVITLSAPIAPSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPY 214
Score = 42.4 bits (98), Expect = 0.004
Identities = 82/330 (24%), Positives = 120/330 (36%), Gaps = 30/330 (9%)
Query: 1280 PPLPPPRPPRPPSPPPEPETTDASHPS---VPPEPLAEDHPPHTPGLCGSLAKSQSTET- 1335
P LPPP P P P + PS + PL P + G L + T
Sbjct: 43 PTLPPPCSPAPQQCPLSAANQASPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTF 102
Query: 1336 VPATPGGEPPLSGGSSGLSLSSPQVPGSPFSYPAPSPSLSSGGL-PRTPGRDFSFTPTF- 1393
+P G PP+S + L+L+SP + + P+ S L+ L P + + +F P
Sbjct: 103 LPNLIG--PPIS--PAALALASPMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLL 158
Query: 1394 -SEP------SGPLLLPVCPLPTGRRDERSGPLASPVLLE-TGLPLPLPLPLPLPLALPA 1445
S P SG ++ P+ + S V+ G P P + +P
Sbjct: 159 TSPPSVAVAESGSVITLSAPIAPSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCVT 218
Query: 1446 VLRAQARAPTPLPPLLP-APLASCPPPMKRKP-GRPRRSP--PSMLSLDGPLVRPPAGAA 1501
+ + LP P LA P +K SP P LSL GP V PPA +
Sbjct: 219 PMASIQSGVASLPQTTPTTTLAIASPQVKDTTISSVLISPQNPGSLSLKGP-VSPPAALS 277
Query: 1502 LGRELLLLPGQPQTPVFPSTHDPRTVTLDFRNAGIP----APPPPLPPQPPPPPPPPPVE 1557
L + L + Q P+T ++L A + L P P V+
Sbjct: 278 LSTQSLPVVTSSQKTAGPNTPPDFPISLGSHLAPLHQSSFGSVQLLGQTGPSALSDPTVK 337
Query: 1558 PTKLPFKELDNQWPSE--AIPPGPRGRDEV 1585
+ +PS+ IPP P R+EV
Sbjct: 338 TISVDHSSTGASYPSQRSVIPPLP-SRNEV 366
Score = 39.3 bits (90), Expect = 0.037
Identities = 37/127 (29%), Positives = 46/127 (36%), Gaps = 13/127 (10%)
Query: 648 SAPITSADCPKPMVVTPGAAAVAAPSVLAPTLPLPPPPGFPPLPPPPPPPPPQPGFPMPP 707
+ P T + P+P T A + S L+ T L P P LPPP P P Q
Sbjct: 8 TVPATEQELPQPQAET---AVLPMSSALSVTAALGQPG--PTLPPPCSPAPQQCPLSAAN 62
Query: 708 PLPPPPPPPPPAHPAVTVPPP------PLPAPPGVPPPPILPPL--PPFPPGLFPVMQVD 759
P P P A + VP P LP P LP L PP P +
Sbjct: 63 QASPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALALASPM 122
Query: 760 MSHVLGG 766
++ L G
Sbjct: 123 IAPTLKG 129
Score = 38.5 bits (88), Expect = 0.064
Identities = 38/144 (26%), Positives = 56/144 (38%), Gaps = 14/144 (9%)
Query: 1219 PADSREPPEEPG---LSQEGAMLLSPEPPAKEVEARP--PLSPERAPEHDLEVEPEPPMM 1273
P PPE L+ + P+P + V A P P+S AP V PP
Sbjct: 1758 PKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPS---PVPTLPPKQ 1814
Query: 1274 LPLPLQPPLPPPRPPRPPSPPPEPETTDASHPSVPPEPLAEDHPPHTPGLCGSLAKSQST 1333
LP P L P +P +P E E P +PPEP++ P + ++ +S
Sbjct: 1815 QFLPSSPGLVLESPSKPLAPADEDELL----PLIPPEPISGGVP--FQSVLVNMPTPKSA 1868
Query: 1334 ETVPATPGGEPPLSGGSSGLSLSS 1357
TP + P++ + G S
Sbjct: 1869 GIPVPTPSAKQPVTKNNKGSGTES 1892
Score = 37.4 bits (85), Expect = 0.14
Identities = 65/249 (26%), Positives = 84/249 (33%), Gaps = 61/249 (24%)
Query: 1331 QSTETVPATPGGEPPLSGGSSGLSLSSPQVPGSPFSYPAPSPSLSSGGLPRTPGRDFSFT 1390
++TETVPAT P ++ L +SS +LS PG
Sbjct: 4 EATETVPATEQELPQPQAETAVLPMSS---------------ALSVTAALGQPG------ 42
Query: 1391 PTFSEPSGPLLLPVCPLPTGRRDERSGPLASPVLLETGLPLPLPLPLPLP-LALPAVLRA 1449
PT P P CPL ++ P SP + PL +P P ALP L
Sbjct: 43 PTLPPPCSP-APQQCPLSAA---NQASPFPSPSTI-ASTPLEVPFPQSSSGTALP--LGT 95
Query: 1450 QARAPTPL-----PPLLPAPLASCPPPM-KRKPGRPRRSPPSMLSLDGP----------- 1492
APT L PP+ PA LA P + G P S P L P
Sbjct: 96 APEAPTFLPNLIGPPISPAALALASPMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPP 155
Query: 1493 --LVRPPAGAALGRELLLLPGQPQTPVFPSTHDPRTVTLDFRNAGIPAPPPPLPPQPPPP 1550
L PP+ A ++ P P P T+ + P + P P
Sbjct: 156 NLLTSPPSVAVAESGSVITLSAPIAPSEPKTN-------------LNKVPSEVVPNPKGT 202
Query: 1551 PPPPPVEPT 1559
P PP + T
Sbjct: 203 PSPPCIVST 211
Score = 33.9 bits (76), Expect = 1.6
Identities = 87/368 (23%), Positives = 123/368 (33%), Gaps = 51/368 (13%)
Query: 1218 EPADSREPPEEPGLSQ---EGAMLLSPEPPAKEVEARPPLSP----ERAPEHDLEVEPEP 1270
+P + PP P Q A SP P + + P P L PE
Sbjct: 40 QPGPTLPPPCSPAPQQCPLSAANQASPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEA 99
Query: 1271 PMMLPLPLQPPLPPPR-PPRPPSPPPEPETTDASHPSVPPEPLAEDHPPHTPGLCGSLAK 1329
P LP + PP+ P P P + T +S + LA PH S+ K
Sbjct: 100 PTFLPNLIGPPISPAALALASPMIAPTLKGTPSSSAPLALVALA----PH------SVQK 149
Query: 1330 SQSTETVPATPGGEPPLSGGSSGLSLSSPQVPGSPFSYPAPSPSLSSGGLPRTPGRD--- 1386
S + T ++ S ++LS+P P P + PS TP
Sbjct: 150 SSAFPPNLLTSPPSVAVAESGSVITLSAPIAPSEPKTNLNKVPSEVVPNPKGTPSPPCIV 209
Query: 1387 -----FSFTPTFSEPSGPLLLPVCPLPTGRRDERSGPLASPVLLETGLPLPLPLPL-PLP 1440
TP S SG LP T + +ASP + +T + L P P
Sbjct: 210 STVPYHCVTPMASIQSGVASLPQTTPTT------TLAIASPQVKDTTISSVLISPQNPGS 263
Query: 1441 LALPAVLRAQARAPTPLPPLLPAPLASCP-PPMKRKPGRPRRSPPSMLSLDGPLVRPPAG 1499
L+L + P P L S P +K P P +SL G + P
Sbjct: 264 LSL--------KGPVSPPAALSLSTQSLPVVTSSQKTAGPNTPPDFPISL-GSHLAPLHQ 314
Query: 1500 AALGRELLLLPGQPQTPVFPSTHDPRTVTLDFRNAGIPAPP-----PPLPPQPPPPPPPP 1554
++ G LL P P+ +T+++D + G P PPLP + P
Sbjct: 315 SSFGSVQLLGQTGPSALSDPTV---KTISVDHSSTGASYPSQRSVIPPLPSRNEVVPATV 371
Query: 1555 PVEPTKLP 1562
P P
Sbjct: 372 AAFPVVAP 379
Score = 33.5 bits (75), Expect = 2.1
Identities = 95/429 (22%), Positives = 146/429 (34%), Gaps = 101/429 (23%)
Query: 365 GPPFK------AQPQDSATFAHTPPPAQATPAPGFKSAFSPYQTPVAHFPPPPEEPTATA 418
GPP A P + T TP ++ AP A +P+ + PP T+
Sbjct: 108 GPPISPAALALASPMIAPTLKGTP----SSSAPLALVALAPHSVQKSS-AFPPNLLTSPP 162
Query: 419 AFGARDSGEFRRAPAPPPLPPAEP------LAKEKPGTPPGPPPPDTNSMELGGRPTFGW 472
+ +SG AP + P+EP + E P G P P + P
Sbjct: 163 SVAVAESGSVITLSAP--IAPSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTV---PYHCV 217
Query: 473 SPEPCDSPG-------TPTLESSPAGPEKPHDSLDSRIEMLLKEQRTKLLFLREPDSDT- 524
+P G TPT + A P+ ++ S +L+ Q L L+ P S
Sbjct: 218 TPMASIQSGVASLPQTTPTTTLAIASPQVKDTTISS---VLISPQNPGSLSLKGPVSPPA 274
Query: 525 --ELQMEGSPISSSS-----------------SQLSPL--APFGTNSQPGFRGPTPPSSR 563
L + P+ +SS S L+PL + FG+ G GP+ S
Sbjct: 275 ALSLSTQSLPVVTSSQKTAGPNTPPDFPISLGSHLAPLHQSSFGSVQLLGQTGPSALSDP 334
Query: 564 PSSTGLEDISPT------------PLPDSDEDEELDLGLGP--RPPPEPGPP-------D 602
T D S T PLP +E + P P + GP
Sbjct: 335 TVKTISVDHSSTGASYPSQRSVIPPLPSRNEVVPATVAAFPVVAPSVDKGPSTISSITCS 394
Query: 603 PAGLLSQTAEVALDLVGDRTPTSEKMDEGQQSSGEDMEISDDEMPSAPITSADCPKPMVV 662
P+G L+ +L +PT+ + + ++ + + P++S P+VV
Sbjct: 395 PSGSLNVATSFSL------SPTTSLILKSSPNATYHYPL----VAQMPVSSVGTT-PLVV 443
Query: 663 TPGAAAVAAPSV-------LAPTLPLPPPPGFPPLPPP--------PPPPPPQPGFPMPP 707
T AAP+ ++P + P P P P P Q +
Sbjct: 444 TNPCTIAAAPTTTFEVATCVSPPMSSGPISNIEPTSPAALVMAPVAPKEPSTQVATTLRI 503
Query: 708 PLPPPPPPP 716
P+ PP P P
Sbjct: 504 PVSPPLPDP 512
>gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]
Length = 1263
Score = 103 bits (257), Expect = 2e-21
Identities = 70/210 (33%), Positives = 82/210 (39%), Gaps = 43/210 (20%)
Query: 555 RGPTPPSSRPSSTGLEDISPTPLPDSDEDEELDLGLGPRPPPEPGPPDPAGLLSQTAEVA 614
R P PP+ I P P P P PPP P PP P G+
Sbjct: 570 RAPVPPAPPLPGDSGTIIPPPPAPGDSTTPP-----PPPPPPPPPPPLPGGVCI------ 618
Query: 615 LDLVGDRTPTSEKMDEGQQSSGEDMEISDDEMPSAPITSADCPKPMVVTPGAAAVAAPSV 674
SS + P P++ P P + +PS
Sbjct: 619 -------------------SSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSS 659
Query: 675 LAPTLPLPPPPGFPPLPPPPPPPPPQPGF----PMPPPLP-----PPPPPPPPAHPAVTV 725
L +PPPP P PPPPPP PG P PPPLP PPPPPP P P +
Sbjct: 660 LPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIP- 718
Query: 726 PPPPLPAPPGVPPPPI---LPPLPPFPPGL 752
PPPP P PG+PPPP +PP PPF G+
Sbjct: 719 PPPPFPGGPGIPPPPPGMGMPPPPPFGFGV 748
Score = 87.0 bits (214), Expect = 2e-16
Identities = 82/263 (31%), Positives = 99/263 (37%), Gaps = 26/263 (9%)
Query: 616 DLVGDRTPT-SEKMDEGQQSSGEDMEISDDEMPSAPITSA--DCPKPMVVTPGAAAVAAP 672
DL G++ SEK + + E+S A +T D K M AA P
Sbjct: 506 DLQGEKDALHSEKQQIATEKQDLEAEVSQLTGEVAKLTKELEDAKKEMASLSAAAITVPP 565
Query: 673 SV--LAPTLPLPPPPGFPPLPPPPPPPPPQPGFPMPPPLPPPPPPPPPAHPAVTVPPPPL 730
SV AP P PP PG PPPP P P PPP PPPPPPP P ++ PP L
Sbjct: 566 SVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCIS-SPPSL 624
Query: 731 PAPPGVPPPP------ILPPLPPFPPGLFPVMQVDMSHVLGGQWGGMPMSFQMQTQV--- 781
P + PPP +PP PP P G V S + GG P ++
Sbjct: 625 PGGTAISPPPPLSGDATIPPPPPLPEG---VGIPSPSSLPGGTAIPPPPPLPGSARIPPP 681
Query: 782 LSRLMTGQGACPYPPFMAAAAA------AASAGLQFVNLPPYRGPFSLSNSGPGRGQHWP 835
L G P PP + A G PP+ G + PG G P
Sbjct: 682 PPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPPPPGMGM--P 739
Query: 836 PLPKFDPSVPPPGYMPRQEDPHK 858
P P F VP +P P K
Sbjct: 740 PPPPFGFGVPAAPVLPFGLTPKK 762
Score = 72.4 bits (176), Expect = 4e-12
Identities = 76/314 (24%), Positives = 117/314 (37%), Gaps = 29/314 (9%)
Query: 1088 EKDEGDSDEEETV--SIVTSKAEATSSSESSESSEFESSSESSPSSSE----DEEEVVAR 1141
EK E + E E S +T++ E + ES +FE + + +++++
Sbjct: 466 EKSEAKAAELEKKLDSELTARHELQVEMKKMES-DFEQKLQDLQGEKDALHSEKQQIATE 524
Query: 1142 EEEEEEEEEEMVAEESMASAGPEDFEQDGEEAALAPGAPAVDSLGMEEEVDIETEAVAPE 1201
+++ E E ++ E + + ED ++ E A+L+ A V + + P
Sbjct: 525 KQDLEAEVSQLTGEVAKLTKELEDAKK--EMASLSAAAITVPP-SVPSRAPVPPAPPLPG 581
Query: 1202 ERPSMLDEPPLPVGVEEPADSREPPEEPGLSQEGAMLLSPE--PPAKEVEARPPLSPERA 1259
+ +++ PP P P PP P G + SP P + PPLS
Sbjct: 582 DSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSG--- 638
Query: 1260 PEHDLEVEPEPPMMLPLPLQPPLPPPRPPRPPSPPPEPETTDASHPSVPPEPLAEDHPPH 1319
D + P PP+ + + P P P PPP P + P PP P + PP
Sbjct: 639 ---DATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPP-PPLPGSAGIPPP 694
Query: 1320 TPGLCGSLAKSQSTETVPATPG--GEPPLSGGSSGLSLSSPQVPGSPFSYPAPSPSLSSG 1377
P L G +P PG PP GG P +P P P P
Sbjct: 695 PPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGG--------PGIPPPPPGMGMPPPPPFGF 746
Query: 1378 GLPRTPGRDFSFTP 1391
G+P P F TP
Sbjct: 747 GVPAAPVLPFGLTP 760
Score = 71.2 bits (173), Expect = 9e-12
Identities = 68/214 (31%), Positives = 82/214 (38%), Gaps = 49/214 (22%)
Query: 1252 PPLSPERAPEHDLEVEPEPPM------MLPLPLQP---PLPPPRPPRPPSPPPEPETTDA 1302
PP P RAP V P PP+ ++P P P PPP PP PP PPP P
Sbjct: 564 PPSVPSRAP-----VPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCI 618
Query: 1303 SHPS--------VPPEPLAEDH--PPHTPGLCGSLAKSQSTETVPATPGG----EPPLSG 1348
S P PP PL+ D PP P L + + + PGG PP
Sbjct: 619 SSPPSLPGGTAISPPPPLSGDATIPPPPP-----LPEGVGIPSPSSLPGGTAIPPPPPLP 673
Query: 1349 GSSGLSLSSPQVPGSPFSYPAPSPSLSSGGLPRTPGRDFSFTPTFSEPSGPLLLPVCPLP 1408
GS+ + P +PGS P P P G+P P P P GP + P P P
Sbjct: 674 GSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPP-------PPL--PGGPGIPPPPPFP 724
Query: 1409 TGRRDERSGPLASPVLLETGLPLPLPLPLPLPLA 1442
GP P G+P P P +P A
Sbjct: 725 -------GGPGIPPPPPGMGMPPPPPFGFGVPAA 751
Score = 68.6 bits (166), Expect = 6e-11
Identities = 87/293 (29%), Positives = 98/293 (33%), Gaps = 109/293 (37%)
Query: 1280 PPLPPPRPPRPPSPPPEPETTDASHPSVPPEPLAEDHPPHTPGLCGSLAKSQSTETVPAT 1339
PP P R P PP+PP + S +PP P D P P
Sbjct: 564 PPSVPSRAPVPPAPPLPGD----SGTIIPPPPAPGDSTTPPPP--------------PPP 605
Query: 1340 PGGEPPLSGGSSGLSLSSPQVPGSPFSYPAPSPSLSSGGLPRTPGRDFSFTPTFSEPSGP 1399
P PPL GG + +SSP PSL GG +P S T P
Sbjct: 606 PPPPPPLPGG---VCISSP-------------PSLP-GGTAISPPPPLSGDATIPPPP-- 646
Query: 1400 LLLPVCPLPTGRRDERSGPLASPVLLETGLPLPLPLPLPLPLALPAVLRAQARAPTPLPP 1459
PLP G + SP L G +P P PLP AR P P PP
Sbjct: 647 ------PLPEGVG------IPSPSSLPGGTAIPPPPPLP----------GSARIPPPPPP 684
Query: 1460 L-----LPAPLASCPPPMKRKPGRPRRSPPSMLSLDGPLVRPPAGAALGRELLLLPGQPQ 1514
L +P P PPP+ + G P PP P G PG P
Sbjct: 685 LPGSAGIPPP----PPPLPGEAGMPPPPPPL-----------PGG----------PGIPP 719
Query: 1515 TPVFPSTHDPRTVTLDFRNAGIPAPPPPLPPQPPPPPPP----PPVEPTKLPF 1563
P FP G P PPP P PPPPP P P LPF
Sbjct: 720 PPPFP---------------GGPGIPPPPPGMGMPPPPPFGFGVPAAPV-LPF 756
Score = 62.0 bits (149), Expect = 5e-09
Identities = 63/199 (31%), Positives = 73/199 (36%), Gaps = 41/199 (20%)
Query: 1396 PSGPLLLPVCPLPTGRRDERSGPLASPVLLETGLPLPLPLPLPLPLALPAVLRAQARAPT 1455
PS P PV P P D + P ++ P P P P P P LP + +
Sbjct: 565 PSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISS---- 620
Query: 1456 PLPPLLPAPLA-SCPPPMKRKPGRPRRSP-------PSMLSLDGPLVRPPAGAALGRELL 1507
PP LP A S PPP+ P P PS SL G PP G +
Sbjct: 621 --PPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARI 678
Query: 1508 LLPGQPQTPVFPSTHDPRTVTLDFRNAGIPAPPPPLPPQPPPPPPPPPVE-----PTKLP 1562
P P P + AGIP PPPPLP + PPPPPP+ P P
Sbjct: 679 ----PPPPPPLPGS------------AGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPP 722
Query: 1563 FKELDNQWPSEAIPPGPRG 1581
F IPP P G
Sbjct: 723 FP------GGPGIPPPPPG 735
Score = 57.4 bits (137), Expect = 1e-07
Identities = 85/310 (27%), Positives = 112/310 (36%), Gaps = 56/310 (18%)
Query: 1126 ESSPSSSEDEEEVVAREEEEEEEEEEMVAEESMASAGPEDFEQ-----DGEEAALAPGAP 1180
+S ++E E+++ + E + EM ES DFEQ GE+ AL
Sbjct: 467 KSEAKAAELEKKLDSELTARHELQVEMKKMES-------DFEQKLQDLQGEKDALHSEKQ 519
Query: 1181 --AVDSLGMEEEVDIETEAVAP--------EERPSMLDEPPLPVGVEEPADSREPPEEPG 1230
A + +E EV T VA ++ + L + V P+ + PP P
Sbjct: 520 QIATEKQDLEAEVSQLTGEVAKLTKELEDAKKEMASLSAAAITVPPSVPSRAPVPPAPPL 579
Query: 1231 LSQEGAMLLSPEPPAKEVEARPPLSPERAPEHDLEVEPEPPMMLPLP-----LQPPLPPP 1285
G ++ P PPA PP P P PP PLP PP P
Sbjct: 580 PGDSGTII--PPPPAPGDSTTPPPPP-----------PPPPPPPPLPGGVCISSPPSLPG 626
Query: 1286 ----RPPRPPS-----PPPEPETTDASHPSVPPEPLAEDHPPHTPGLCGSLAKSQSTETV 1336
PP P S PPP P PS P PP P L GS +
Sbjct: 627 GTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPP-PPPLPGSARIPPPPPPL 685
Query: 1337 PATPG--GEPPLSGGSSGLSLSSPQVPGSPFSYPAPSPSLSSGGL-PRTPGRDFSFTPT- 1392
P + G PP G +G+ P +PG P P P P G+ P PG P
Sbjct: 686 PGSAGIPPPPPPLPGEAGMPPPPPPLPGGP-GIPPPPPFPGGPGIPPPPPGMGMPPPPPF 744
Query: 1393 -FSEPSGPLL 1401
F P+ P+L
Sbjct: 745 GFGVPAAPVL 754
Score = 53.1 bits (126), Expect = 3e-06
Identities = 77/306 (25%), Positives = 92/306 (30%), Gaps = 107/306 (34%)
Query: 434 PPPLPPAEPLAKEKPGTPPGPPPPDTNSMELGGRPTFGWSPEPCDSPGTPTLESSPAGPE 493
PP +P P+ PP PP P + G P +PG T P P
Sbjct: 564 PPSVPSRAPV-------PPAPPLPGDS----------GTIIPPPPAPGDSTTPPPPPPPP 606
Query: 494 KPHDSLDSRIEMLLKEQRTKLLFLREPDSDTELQMEGSPISSSSSQLSPLAPFGTNSQPG 553
P L + P + P S + + P P P
Sbjct: 607 PPPPPLPGGV-----------CISSPPSLPGGTAISPPPPLSGDATIPPPPPL-----PE 650
Query: 554 FRGPTPPSSRPSSTGLEDISPTPLPDSDEDEELDLGLGPRPPPEPG----PPDPAGLLSQ 609
G PSS P T + P PLP S + P PPP PG PP P L +
Sbjct: 651 GVGIPSPSSLPGGTAIP--PPPPLPGSAR-------IPPPPPPLPGSAGIPPPPPPLPGE 701
Query: 610 TAEVALDLVGDRTPTSEKMDEGQQSSGEDMEISDDEMPSAPITSADCPKPMVVTPGAAAV 669
A P P PG
Sbjct: 702 --------------------------------------------AGMPPPPPPLPG---- 713
Query: 670 AAPSVLAPTLPLPPP-PGFPPLPPPPP----PPPPQPGFPMP--PPLPPPPPPPPPAHPA 722
P +P PPP PG P +PPPPP PPPP GF +P P LP P P
Sbjct: 714 ------GPGIPPPPPFPGGPGIPPPPPGMGMPPPPPFGFGVPAAPVLPFGLTPKKLYKPE 767
Query: 723 VTVPPP 728
V + P
Sbjct: 768 VQLRRP 773
Score = 45.1 bits (105), Expect = 7e-04
Identities = 45/146 (30%), Positives = 50/146 (34%), Gaps = 40/146 (27%)
Query: 358 GGTGGSSGPPFKAQPQDSATFAHTPPPAQATPAPGFKSAFS-PYQTPVAHFPPPPEEPTA 416
GGT S PP A PPP G S S P T + PPPP P +
Sbjct: 626 GGTAISPPPPLSGD-------ATIPPPPPLPEGVGIPSPSSLPGGTAI---PPPPPLPGS 675
Query: 417 TAAFGARDSGEFRRAPAPPP-------LPPAEPLAKEKPGTPPGPPPPDTNSMELGGRPT 469
R P PPP +PP P + G PP PPP L G P
Sbjct: 676 A------------RIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPP-------LPGGPG 716
Query: 470 FGWSPEPCDSPGTPTLESSPAGPEKP 495
P P PG P + P G P
Sbjct: 717 I---PPPPPFPGGPGIPPPPPGMGMP 739
Score = 44.7 bits (104), Expect = 9e-04
Identities = 46/166 (27%), Positives = 52/166 (31%), Gaps = 36/166 (21%)
Query: 353 PFGAVGGTGGSSGPPFKAQPQDSATFAHTPPPAQATPAPGFKSAFSPYQTP--VAHFPPP 410
P + G G+ PP A + PPP P PG SP P A PPP
Sbjct: 575 PAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPP 634
Query: 411 PEEPTATAAFGARDSGEFRRAPAPPPLP------------------PAEPLAKEKPGTPP 452
P AT P PPPLP P PL PP
Sbjct: 635 PLSGDATI-------------PPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPP 681
Query: 453 GPPPPDTNSMELGGRP---TFGWSPEPCDSPGTPTLESSPAGPEKP 495
PP P + + P G P P PG P + P P P
Sbjct: 682 PPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGP 727
Score = 43.5 bits (101), Expect = 0.002
Identities = 61/224 (27%), Positives = 70/224 (31%), Gaps = 82/224 (36%)
Query: 399 PYQTPVAHFPPPPEEPTATAAFGARDSGEFRRAPAPPPLPPAEPLAKEKPGTPPGPPPPD 458
P + PV PP P DSG PPP P + P PP PPPP
Sbjct: 568 PSRAPVPPAPPLPG-----------DSGTI----IPPPPAPGDSTTPPPPPPPPPPPPPL 612
Query: 459 TNSMELGGRPTF----GWSPEPCDSPGTPTLESSPAGPEKPHDSLDSRIEMLLKEQRTKL 514
+ + P+ SP P S G T+ P P
Sbjct: 613 PGGVCISSPPSLPGGTAISPPPPLS-GDATIPPPPPLP---------------------- 649
Query: 515 LFLREPDSDTELQMEGSPISSSSSQLSPLAPFGTNSQP------GFRGPTPPSSRPSSTG 568
EG I S SS P GT P R P PP P S G
Sbjct: 650 --------------EGVGIPSPSS-----LPGGTAIPPPPPLPGSARIPPPPPPLPGSAG 690
Query: 569 LEDISPTPLPDSDEDEELDLGLGPRPPPEPG-------PPDPAG 605
+ P PLP + G+ P PPP PG PP P G
Sbjct: 691 IPP-PPPPLPG-------EAGMPPPPPPLPGGPGIPPPPPFPGG 726
Score = 31.6 bits (70), Expect = 7.8
Identities = 36/123 (29%), Positives = 44/123 (35%), Gaps = 21/123 (17%)
Query: 361 GGSSGPPFKAQPQDSATFAHTPPPAQATPAPGFKSAFSPYQTPV---AHFPPPPEEPTAT 417
GG++ PP P A PPP P PG + P P+ A PPPP P
Sbjct: 662 GGTAIPP----PPPLPGSARIPPPPP--PLPG-SAGIPPPPPPLPGEAGMPPPP--PPLP 712
Query: 418 AAFGARDSGEFRRAPAPPPLPPAEPLAKEKPGTPPGPPPPDTNSMELGGRPTFGWSPEPC 477
G F P P +PP PG PPPP + FG +P+
Sbjct: 713 GGPGIPPPPPF---PGGPGIPP------PPPGMGMPPPPPFGFGVPAAPVLPFGLTPKKL 763
Query: 478 DSP 480
P
Sbjct: 764 YKP 766
>gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]
Length = 1272
Score = 103 bits (257), Expect = 2e-21
Identities = 70/210 (33%), Positives = 82/210 (39%), Gaps = 43/210 (20%)
Query: 555 RGPTPPSSRPSSTGLEDISPTPLPDSDEDEELDLGLGPRPPPEPGPPDPAGLLSQTAEVA 614
R P PP+ I P P P P PPP P PP P G+
Sbjct: 579 RAPVPPAPPLPGDSGTIIPPPPAPGDSTTPP-----PPPPPPPPPPPLPGGVCI------ 627
Query: 615 LDLVGDRTPTSEKMDEGQQSSGEDMEISDDEMPSAPITSADCPKPMVVTPGAAAVAAPSV 674
SS + P P++ P P + +PS
Sbjct: 628 -------------------SSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSS 668
Query: 675 LAPTLPLPPPPGFPPLPPPPPPPPPQPGF----PMPPPLP-----PPPPPPPPAHPAVTV 725
L +PPPP P PPPPPP PG P PPPLP PPPPPP P P +
Sbjct: 669 LPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIP- 727
Query: 726 PPPPLPAPPGVPPPPI---LPPLPPFPPGL 752
PPPP P PG+PPPP +PP PPF G+
Sbjct: 728 PPPPFPGGPGIPPPPPGMGMPPPPPFGFGV 757
Score = 87.0 bits (214), Expect = 2e-16
Identities = 82/263 (31%), Positives = 99/263 (37%), Gaps = 26/263 (9%)
Query: 616 DLVGDRTPT-SEKMDEGQQSSGEDMEISDDEMPSAPITSA--DCPKPMVVTPGAAAVAAP 672
DL G++ SEK + + E+S A +T D K M AA P
Sbjct: 515 DLQGEKDALHSEKQQIATEKQDLEAEVSQLTGEVAKLTKELEDAKKEMASLSAAAITVPP 574
Query: 673 SV--LAPTLPLPPPPGFPPLPPPPPPPPPQPGFPMPPPLPPPPPPPPPAHPAVTVPPPPL 730
SV AP P PP PG PPPP P P PPP PPPPPPP P ++ PP L
Sbjct: 575 SVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCIS-SPPSL 633
Query: 731 PAPPGVPPPP------ILPPLPPFPPGLFPVMQVDMSHVLGGQWGGMPMSFQMQTQV--- 781
P + PPP +PP PP P G V S + GG P ++
Sbjct: 634 PGGTAISPPPPLSGDATIPPPPPLPEG---VGIPSPSSLPGGTAIPPPPPLPGSARIPPP 690
Query: 782 LSRLMTGQGACPYPPFMAAAAA------AASAGLQFVNLPPYRGPFSLSNSGPGRGQHWP 835
L G P PP + A G PP+ G + PG G P
Sbjct: 691 PPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPPPPGMGM--P 748
Query: 836 PLPKFDPSVPPPGYMPRQEDPHK 858
P P F VP +P P K
Sbjct: 749 PPPPFGFGVPAAPVLPFGLTPKK 771
Score = 72.4 bits (176), Expect = 4e-12
Identities = 76/314 (24%), Positives = 117/314 (37%), Gaps = 29/314 (9%)
Query: 1088 EKDEGDSDEEETV--SIVTSKAEATSSSESSESSEFESSSESSPSSSE----DEEEVVAR 1141
EK E + E E S +T++ E + ES +FE + + +++++
Sbjct: 475 EKSEAKAAELEKKLDSELTARHELQVEMKKMES-DFEQKLQDLQGEKDALHSEKQQIATE 533
Query: 1142 EEEEEEEEEEMVAEESMASAGPEDFEQDGEEAALAPGAPAVDSLGMEEEVDIETEAVAPE 1201
+++ E E ++ E + + ED ++ E A+L+ A V + + P
Sbjct: 534 KQDLEAEVSQLTGEVAKLTKELEDAKK--EMASLSAAAITVPP-SVPSRAPVPPAPPLPG 590
Query: 1202 ERPSMLDEPPLPVGVEEPADSREPPEEPGLSQEGAMLLSPE--PPAKEVEARPPLSPERA 1259
+ +++ PP P P PP P G + SP P + PPLS
Sbjct: 591 DSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSG--- 647
Query: 1260 PEHDLEVEPEPPMMLPLPLQPPLPPPRPPRPPSPPPEPETTDASHPSVPPEPLAEDHPPH 1319
D + P PP+ + + P P P PPP P + P PP P + PP
Sbjct: 648 ---DATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPP-PPLPGSAGIPPP 703
Query: 1320 TPGLCGSLAKSQSTETVPATPG--GEPPLSGGSSGLSLSSPQVPGSPFSYPAPSPSLSSG 1377
P L G +P PG PP GG P +P P P P
Sbjct: 704 PPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGG--------PGIPPPPPGMGMPPPPPFGF 755
Query: 1378 GLPRTPGRDFSFTP 1391
G+P P F TP
Sbjct: 756 GVPAAPVLPFGLTP 769
Score = 71.2 bits (173), Expect = 9e-12
Identities = 68/214 (31%), Positives = 82/214 (38%), Gaps = 49/214 (22%)
Query: 1252 PPLSPERAPEHDLEVEPEPPM------MLPLPLQP---PLPPPRPPRPPSPPPEPETTDA 1302
PP P RAP V P PP+ ++P P P PPP PP PP PPP P
Sbjct: 573 PPSVPSRAP-----VPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCI 627
Query: 1303 SHPS--------VPPEPLAEDH--PPHTPGLCGSLAKSQSTETVPATPGG----EPPLSG 1348
S P PP PL+ D PP P L + + + PGG PP
Sbjct: 628 SSPPSLPGGTAISPPPPLSGDATIPPPPP-----LPEGVGIPSPSSLPGGTAIPPPPPLP 682
Query: 1349 GSSGLSLSSPQVPGSPFSYPAPSPSLSSGGLPRTPGRDFSFTPTFSEPSGPLLLPVCPLP 1408
GS+ + P +PGS P P P G+P P P P GP + P P P
Sbjct: 683 GSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPP-------PPL--PGGPGIPPPPPFP 733
Query: 1409 TGRRDERSGPLASPVLLETGLPLPLPLPLPLPLA 1442
GP P G+P P P +P A
Sbjct: 734 -------GGPGIPPPPPGMGMPPPPPFGFGVPAA 760
Score = 68.6 bits (166), Expect = 6e-11
Identities = 87/293 (29%), Positives = 98/293 (33%), Gaps = 109/293 (37%)
Query: 1280 PPLPPPRPPRPPSPPPEPETTDASHPSVPPEPLAEDHPPHTPGLCGSLAKSQSTETVPAT 1339
PP P R P PP+PP + S +PP P D P P
Sbjct: 573 PPSVPSRAPVPPAPPLPGD----SGTIIPPPPAPGDSTTPPPP--------------PPP 614
Query: 1340 PGGEPPLSGGSSGLSLSSPQVPGSPFSYPAPSPSLSSGGLPRTPGRDFSFTPTFSEPSGP 1399
P PPL GG + +SSP PSL GG +P S T P
Sbjct: 615 PPPPPPLPGG---VCISSP-------------PSLP-GGTAISPPPPLSGDATIPPPP-- 655
Query: 1400 LLLPVCPLPTGRRDERSGPLASPVLLETGLPLPLPLPLPLPLALPAVLRAQARAPTPLPP 1459
PLP G + SP L G +P P PLP AR P P PP
Sbjct: 656 ------PLPEGVG------IPSPSSLPGGTAIPPPPPLP----------GSARIPPPPPP 693
Query: 1460 L-----LPAPLASCPPPMKRKPGRPRRSPPSMLSLDGPLVRPPAGAALGRELLLLPGQPQ 1514
L +P P PPP+ + G P PP P G PG P
Sbjct: 694 LPGSAGIPPP----PPPLPGEAGMPPPPPPL-----------PGG----------PGIPP 728
Query: 1515 TPVFPSTHDPRTVTLDFRNAGIPAPPPPLPPQPPPPPPP----PPVEPTKLPF 1563
P FP G P PPP P PPPPP P P LPF
Sbjct: 729 PPPFP---------------GGPGIPPPPPGMGMPPPPPFGFGVPAAPV-LPF 765
Score = 62.0 bits (149), Expect = 5e-09
Identities = 63/199 (31%), Positives = 73/199 (36%), Gaps = 41/199 (20%)
Query: 1396 PSGPLLLPVCPLPTGRRDERSGPLASPVLLETGLPLPLPLPLPLPLALPAVLRAQARAPT 1455
PS P PV P P D + P ++ P P P P P P LP + +
Sbjct: 574 PSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISS---- 629
Query: 1456 PLPPLLPAPLA-SCPPPMKRKPGRPRRSP-------PSMLSLDGPLVRPPAGAALGRELL 1507
PP LP A S PPP+ P P PS SL G PP G +
Sbjct: 630 --PPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARI 687
Query: 1508 LLPGQPQTPVFPSTHDPRTVTLDFRNAGIPAPPPPLPPQPPPPPPPPPVE-----PTKLP 1562
P P P + AGIP PPPPLP + PPPPPP+ P P
Sbjct: 688 ----PPPPPPLPGS------------AGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPP 731
Query: 1563 FKELDNQWPSEAIPPGPRG 1581
F IPP P G
Sbjct: 732 FP------GGPGIPPPPPG 744
Score = 57.4 bits (137), Expect = 1e-07
Identities = 85/310 (27%), Positives = 112/310 (36%), Gaps = 56/310 (18%)
Query: 1126 ESSPSSSEDEEEVVAREEEEEEEEEEMVAEESMASAGPEDFEQ-----DGEEAALAPGAP 1180
+S ++E E+++ + E + EM ES DFEQ GE+ AL
Sbjct: 476 KSEAKAAELEKKLDSELTARHELQVEMKKMES-------DFEQKLQDLQGEKDALHSEKQ 528
Query: 1181 --AVDSLGMEEEVDIETEAVAP--------EERPSMLDEPPLPVGVEEPADSREPPEEPG 1230
A + +E EV T VA ++ + L + V P+ + PP P
Sbjct: 529 QIATEKQDLEAEVSQLTGEVAKLTKELEDAKKEMASLSAAAITVPPSVPSRAPVPPAPPL 588
Query: 1231 LSQEGAMLLSPEPPAKEVEARPPLSPERAPEHDLEVEPEPPMMLPLP-----LQPPLPPP 1285
G ++ P PPA PP P P PP PLP PP P
Sbjct: 589 PGDSGTII--PPPPAPGDSTTPPPPP-----------PPPPPPPPLPGGVCISSPPSLPG 635
Query: 1286 ----RPPRPPS-----PPPEPETTDASHPSVPPEPLAEDHPPHTPGLCGSLAKSQSTETV 1336
PP P S PPP P PS P PP P L GS +
Sbjct: 636 GTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPP-PPPLPGSARIPPPPPPL 694
Query: 1337 PATPG--GEPPLSGGSSGLSLSSPQVPGSPFSYPAPSPSLSSGGL-PRTPGRDFSFTPT- 1392
P + G PP G +G+ P +PG P P P P G+ P PG P
Sbjct: 695 PGSAGIPPPPPPLPGEAGMPPPPPPLPGGP-GIPPPPPFPGGPGIPPPPPGMGMPPPPPF 753
Query: 1393 -FSEPSGPLL 1401
F P+ P+L
Sbjct: 754 GFGVPAAPVL 763
Score = 53.1 bits (126), Expect = 3e-06
Identities = 77/306 (25%), Positives = 92/306 (30%), Gaps = 107/306 (34%)
Query: 434 PPPLPPAEPLAKEKPGTPPGPPPPDTNSMELGGRPTFGWSPEPCDSPGTPTLESSPAGPE 493
PP +P P+ PP PP P + G P +PG T P P
Sbjct: 573 PPSVPSRAPV-------PPAPPLPGDS----------GTIIPPPPAPGDSTTPPPPPPPP 615
Query: 494 KPHDSLDSRIEMLLKEQRTKLLFLREPDSDTELQMEGSPISSSSSQLSPLAPFGTNSQPG 553
P L + P + P S + + P P P
Sbjct: 616 PPPPPLPGGV-----------CISSPPSLPGGTAISPPPPLSGDATIPPPPPL-----PE 659
Query: 554 FRGPTPPSSRPSSTGLEDISPTPLPDSDEDEELDLGLGPRPPPEPG----PPDPAGLLSQ 609
G PSS P T + P PLP S + P PPP PG PP P L +
Sbjct: 660 GVGIPSPSSLPGGTAIP--PPPPLPGSAR-------IPPPPPPLPGSAGIPPPPPPLPGE 710
Query: 610 TAEVALDLVGDRTPTSEKMDEGQQSSGEDMEISDDEMPSAPITSADCPKPMVVTPGAAAV 669
A P P PG
Sbjct: 711 --------------------------------------------AGMPPPPPPLPG---- 722
Query: 670 AAPSVLAPTLPLPPP-PGFPPLPPPPP----PPPPQPGFPMP--PPLPPPPPPPPPAHPA 722
P +P PPP PG P +PPPPP PPPP GF +P P LP P P
Sbjct: 723 ------GPGIPPPPPFPGGPGIPPPPPGMGMPPPPPFGFGVPAAPVLPFGLTPKKLYKPE 776
Query: 723 VTVPPP 728
V + P
Sbjct: 777 VQLRRP 782
Score = 45.1 bits (105), Expect = 7e-04
Identities = 45/146 (30%), Positives = 50/146 (34%), Gaps = 40/146 (27%)
Query: 358 GGTGGSSGPPFKAQPQDSATFAHTPPPAQATPAPGFKSAFS-PYQTPVAHFPPPPEEPTA 416
GGT S PP A PPP G S S P T + PPPP P +
Sbjct: 635 GGTAISPPPPLSGD-------ATIPPPPPLPEGVGIPSPSSLPGGTAI---PPPPPLPGS 684
Query: 417 TAAFGARDSGEFRRAPAPPP-------LPPAEPLAKEKPGTPPGPPPPDTNSMELGGRPT 469
R P PPP +PP P + G PP PPP L G P
Sbjct: 685 A------------RIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPP-------LPGGPG 725
Query: 470 FGWSPEPCDSPGTPTLESSPAGPEKP 495
P P PG P + P G P
Sbjct: 726 I---PPPPPFPGGPGIPPPPPGMGMP 748
Score = 44.7 bits (104), Expect = 9e-04
Identities = 46/166 (27%), Positives = 52/166 (31%), Gaps = 36/166 (21%)
Query: 353 PFGAVGGTGGSSGPPFKAQPQDSATFAHTPPPAQATPAPGFKSAFSPYQTP--VAHFPPP 410
P + G G+ PP A + PPP P PG SP P A PPP
Sbjct: 584 PAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPP 643
Query: 411 PEEPTATAAFGARDSGEFRRAPAPPPLP------------------PAEPLAKEKPGTPP 452
P AT P PPPLP P PL PP
Sbjct: 644 PLSGDATI-------------PPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPP 690
Query: 453 GPPPPDTNSMELGGRP---TFGWSPEPCDSPGTPTLESSPAGPEKP 495
PP P + + P G P P PG P + P P P
Sbjct: 691 PPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGP 736
Score = 43.5 bits (101), Expect = 0.002
Identities = 61/224 (27%), Positives = 70/224 (31%), Gaps = 82/224 (36%)
Query: 399 PYQTPVAHFPPPPEEPTATAAFGARDSGEFRRAPAPPPLPPAEPLAKEKPGTPPGPPPPD 458
P + PV PP P DSG PPP P + P PP PPPP
Sbjct: 577 PSRAPVPPAPPLPG-----------DSGTI----IPPPPAPGDSTTPPPPPPPPPPPPPL 621
Query: 459 TNSMELGGRPTF----GWSPEPCDSPGTPTLESSPAGPEKPHDSLDSRIEMLLKEQRTKL 514
+ + P+ SP P S G T+ P P
Sbjct: 622 PGGVCISSPPSLPGGTAISPPPPLS-GDATIPPPPPLP---------------------- 658
Query: 515 LFLREPDSDTELQMEGSPISSSSSQLSPLAPFGTNSQP------GFRGPTPPSSRPSSTG 568
EG I S SS P GT P R P PP P S G
Sbjct: 659 --------------EGVGIPSPSS-----LPGGTAIPPPPPLPGSARIPPPPPPLPGSAG 699
Query: 569 LEDISPTPLPDSDEDEELDLGLGPRPPPEPG-------PPDPAG 605
+ P PLP + G+ P PPP PG PP P G
Sbjct: 700 IPP-PPPPLPG-------EAGMPPPPPPLPGGPGIPPPPPFPGG 735
Score = 31.6 bits (70), Expect = 7.8
Identities = 36/123 (29%), Positives = 44/123 (35%), Gaps = 21/123 (17%)
Query: 361 GGSSGPPFKAQPQDSATFAHTPPPAQATPAPGFKSAFSPYQTPV---AHFPPPPEEPTAT 417
GG++ PP P A PPP P PG + P P+ A PPPP P
Sbjct: 671 GGTAIPP----PPPLPGSARIPPPPP--PLPG-SAGIPPPPPPLPGEAGMPPPP--PPLP 721
Query: 418 AAFGARDSGEFRRAPAPPPLPPAEPLAKEKPGTPPGPPPPDTNSMELGGRPTFGWSPEPC 477
G F P P +PP PG PPPP + FG +P+
Sbjct: 722 GGPGIPPPPPF---PGGPGIPP------PPPGMGMPPPPPFGFGVPAAPVLPFGLTPKKL 772
Query: 478 DSP 480
P
Sbjct: 773 YKP 775
>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
Length = 1012
Score = 103 bits (257), Expect = 2e-21
Identities = 161/597 (26%), Positives = 213/597 (35%), Gaps = 123/597 (20%)
Query: 1068 SDDRDESENDDEDTALSEASEKDEGDSDEEETVSIVTSKAEATSSSESSESSEFESSSES 1127
+D + E+ EAS + + + E V+ T +A+ TSS ++ E S +
Sbjct: 68 NDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQ---EISRPN 124
Query: 1128 SPSSSEDEEEVVAREEEEEEEEEEMVAEESMASAGPEDFEQDGEEAALAPGAPAVDSLGM 1187
SPS E E E + V +E S+ P+D +QD + P P+
Sbjct: 125 SPS-----------EGEGESSDSRSVNDEG--SSDPKDIDQDNRSTS--PSIPSPQ---- 165
Query: 1188 EEEVDIETEAVAPEERPSMLDEPPL---PVGVEEPADSREPPEEPGLSQEGAMLLSPEPP 1244
D E+++ + ++ + +PP P GV PA S PP P L G P P
Sbjct: 166 ----DNESDSDSSAQQQMLQAQPPALQAPTGVT-PAPSSAPPGTPQLPTPG-----PTPS 215
Query: 1245 AKEVEARPPLSPERAPEHDLEVEPEPPMMLPLPLQ--PPLPPPRPPRPPSPPPEPETTDA 1302
A V + + +AP +P+ P P+P P P RPPSP P P
Sbjct: 216 ATAVPPQGSPTASQAPN-----QPQAPTA-PVPHTHIQQAPALHPQRPPSPHPPP----- 264
Query: 1303 SHPSVPPEPLAEDHPPHTPGLCGSLAKSQSTETVPATPG-GEPPLSGGSSGLSLSSPQVP 1361
HPS HPP P L GS + P+ P +PPL G Q P
Sbjct: 265 -HPS--------PHPPLQP-LTGSAGQ-------PSAPSHAQPPLHG----------QGP 297
Query: 1362 GSPFSYPAPSPSLSSGGLPRTPGRDFSFTPTFSEPSGPLLLPVCPLPTGRRDERSGPLAS 1421
P S A P L G P + F P S+ PL P P +
Sbjct: 298 PGPHSLQA-GPLLQHPG----PPQPFGLPPQASQGQAPL--GTSPAAAYPHTSLQLPASQ 350
Query: 1422 PVLLETGLPLPLPLPLPLPLALPAVLRAQARAPTPLPPLLPAPLASCPPPMKRKPGR--- 1478
L P PLP P PLA+P + PT P LPAP A PP P
Sbjct: 351 SALQSQQPPREQPLP-PAPLAMPHI----KPPPTTPIPQLPAPQAHKHPPHLSGPSPFSM 405
Query: 1479 -------PRRSPPSMLSLDGPLVRPPAGAALGRELLLLPGQPQTPVF----------PST 1521
P P S LS P P L + LP P P P++
Sbjct: 406 NANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPAS 465
Query: 1522 HDPRTVTLDFRNAGIPAPPPPLPPQPPPPPPPPPVEPTKLPFKELDNQWPSEAIPPGPRG 1581
H P + AP PP P P PPP+ P P P + P G
Sbjct: 466 HPPTGLHQ-------VAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSG 518
Query: 1582 RDEVTEEYMELAKSRGPWRRPPKKRHEDLVPPAGSPELSPPQPLFRPRSEFEEMTIL 1638
S P P + E+ + A PE SPP P PRS E T++
Sbjct: 519 --AAASGGSIAGGSSCP--LPTVQIKEEALDDAEEPE-SPPPP---PRSPSPEPTVV 567
Score = 83.2 bits (204), Expect = 2e-15
Identities = 132/535 (24%), Positives = 170/535 (31%), Gaps = 143/535 (26%)
Query: 362 GSSGPPFKAQPQDSATFAHTPPPAQATPAPGFKSAFSPYQTPVAHFPPPPEEPTATAAFG 421
GSS P K QD+ + + + P Q + SA Q + PP + PT
Sbjct: 143 GSSDP--KDIDQDNRSTSPSIPSPQDNESDSDSSA---QQQMLQAQPPALQAPTGVT--- 194
Query: 422 ARDSGEFRRAPAPPPLPPAEPLAKEKPGTPPGPPPPDTNSMELGGRPTFGWSPEPCDSPG 481
PAP PP P PGP P T ++ G PT +P +P
Sbjct: 195 ----------PAPSSAPPGTPQLPT-----PGPTPSAT-AVPPQGSPTASQAPNQPQAPT 238
Query: 482 TPT----LESSPA----GPEKPHDSLDSRIEMLLKEQRTKLLFLREPDSDTELQMEGSPI 533
P ++ +PA P PH P LQ P+
Sbjct: 239 APVPHTHIQQAPALHPQRPPSPHPP-------------------PHPSPHPPLQ----PL 275
Query: 534 SSSSSQLSPLAPFGTNSQPGFRGPTPPSSRPSSTGLEDISPTPLPDSDEDEELDLGLGPR 593
+ S+ Q P AP +++QP G PP G PL
Sbjct: 276 TGSAGQ--PSAP--SHAQPPLHGQGPPGPHSLQAG-------PLLQ-------------- 310
Query: 594 PPPEPGPPDPAGLLSQTAEVALDL----VGDRTPTSEKMDEGQQSSGEDMEISDDEMPSA 649
PGPP P GL Q ++ L TS ++ Q + + +P A
Sbjct: 311 ---HPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPA 367
Query: 650 PITSADC------PKPMVVTPGAAA----VAAPSVLAPTLPLPPPPGFPPLP------PP 693
P+ P P + P A ++ PS + LPPPP PL PP
Sbjct: 368 PLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPP 427
Query: 694 PPPPPPQPGFPMPPPLPPPPPPPPPAHPAVTVPPPPLPAPPG-----VPPPPILPPLPPF 748
PPP P PLP P PP + +PPPP PP P PP PF
Sbjct: 428 SAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQ--HPF 485
Query: 749 PPGLFPVMQVDMSHVLGGQWGGMPMSFQMQTQVLSRLMTGQGACPYPPFMAAAAAAAS-A 807
P GG P S G G PP AAA+ S A
Sbjct: 486 VP------------------GGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIA 527
Query: 808 GLQFVNLPPYRGPFSLSNSGPGRGQHWPPLPKFDPSVPPPGYMPRQEDPHKATVD 862
G LP + + +P PPP PR P VD
Sbjct: 528 GGSSCPLPTVQIKEEALDDAE------------EPESPPP--PPRSPSPEPTVVD 568
Score = 68.9 bits (167), Expect = 4e-11
Identities = 108/435 (24%), Positives = 147/435 (33%), Gaps = 106/435 (24%)
Query: 445 KEKPGTPPGPPPPDTNSMELGGRPTFGWSPEPCDSPGTPTLESSPAGPEKPHDSLDSRIE 504
K++P +P G P + GR +SP + S+ DS+ E
Sbjct: 35 KKQPASPDGRTSPINEDIRSSGR----------NSPSAASTSSN-----------DSKAE 73
Query: 505 MLLKEQRTKLLFLREPDSDTELQMEGSPISSSSSQLSPLAPFGTNSQPGFRGPTPPSSRP 564
+ K + ++E S SP+ S+ Q +A T + R
Sbjct: 74 TVKKSAKK----VKEEAS--------SPLKSNKRQREKVA-----------SDTEEADRT 110
Query: 565 SS--TGLEDISPTPLPDSDEDEELDLGLGPRPPPEPGPPDPAGLLSQTAEVALDLVGDRT 622
SS T ++IS P E E D R + G DP D+ D
Sbjct: 111 SSKKTKTQEISRPNSPSEGEGESSD----SRSVNDEGSSDPK-----------DIDQDNR 155
Query: 623 PTSEKMDEGQQSSGEDMEISDDEMPSAPITSADCPKPMVVTPGAAAVAAPSVLAPTLPLP 682
TS + Q + + + +M A + P + P +A P + P P P
Sbjct: 156 STSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPG-PTP 214
Query: 683 -----PPPGFPPL------PPPPPPPPPQPGFPMPPPLPP--PPPPPPPAHPAVTVPPPP 729
PP G P P P P P P L P PP P PP HP+ P P
Sbjct: 215 SATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQP 274
Query: 730 LPAPPGVPPPP--ILPPL----PPFPPGLF--PVMQVDMSHVLGGQWGGMPMSFQMQTQV 781
L G P P PPL PP P L P++Q G P F + Q
Sbjct: 275 LTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHP----------GPPQPFGLPPQA 324
Query: 782 LSRLMTGQGACPYPPFMAAAAAAASAGLQFVNLPPYRGPFSLSNSGPGRGQHWPPLPKFD 841
QG P AAA S + LP + +L + P R Q PP P
Sbjct: 325 ------SQGQAPLGTSPAAAYPHTS-----LQLPASQS--ALQSQQPPREQPLPPAPLAM 371
Query: 842 PSVPPPGYMPRQEDP 856
P + PP P + P
Sbjct: 372 PHIKPPPTTPIPQLP 386
Score = 60.1 bits (144), Expect = 2e-08
Identities = 97/396 (24%), Positives = 123/396 (31%), Gaps = 72/396 (18%)
Query: 384 PAQATPAPGFKSAFSPYQTPVAHFPPPPEEPTATAAFGARDSGEFRRAPAPPPLPPAEPL 443
PA ++ PG +P TP A PP PTA+ A + + AP P +
Sbjct: 195 PAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQA-----PNQPQAPTAPVPHTHIQQA 249
Query: 444 AKEKPGTPPGPPPPDTNSMELGGRPTFGWSPEP-CDSPGTPTLESSPAGPEKPHDSLDSR 502
P PP P PP S +P G + +P S P L GP PH +
Sbjct: 250 PALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQ--GPPGPHSL---Q 304
Query: 503 IEMLLKEQRTKLLFLREPD-SDTELQMEGSPISS---SSSQLSPLAPFGTNSQPGFRGPT 558
LL+ F P S + + SP ++ +S QL + QP P
Sbjct: 305 AGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPL 364
Query: 559 PPSSRPSSTGLEDISP---TPLPDSDEDEELDLGLGPRPPPEPGPPDP----AGLLSQTA 611
PP+ + I P TP+P +L + PP P P A L A
Sbjct: 365 PPAP----LAMPHIKPPPTTPIP------QLPAPQAHKHPPHLSGPSPFSMNANLPPPPA 414
Query: 612 EVALDLVGDRTPTSEKMDEGQQSSGEDMEISDDEMPSAPITSADCPKPMVVTPGAA---- 667
L + P S Q S P S + P P P
Sbjct: 415 LKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQV 474
Query: 668 AVAAPSVLAPTLPLPPPPGFPPLPPPPPPPPPQPGFPMPPPL------------------ 709
A P P +P PPP PP P PP PG PP
Sbjct: 475 APQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPL 534
Query: 710 ------------------PPPPPPPPPAHPAVTVPP 727
PPPPP P P V P
Sbjct: 535 PTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTP 570
Score = 33.9 bits (76), Expect = 1.6
Identities = 52/226 (23%), Positives = 78/226 (34%), Gaps = 32/226 (14%)
Query: 1119 SEFESSSESSPSSSEDEEEVVAREEEEEEEEEEMVAEESMASAGPEDFEQDGEEAALAPG 1178
S+ E + ++ E E AREE E E+E+E E + E++ E AA A
Sbjct: 603 SKLAKKREEAIEKAKREAEQKAREEREREKEKEKERERE------REREREAERAAKASS 656
Query: 1179 APAVDSLGMEEEVDIETEAVAPEERPSMLDEPPLPVGVEEPA----------------DS 1222
+ L + + E P+ + P +G + PA +
Sbjct: 657 SAHEGRLSDPQLSGPGHMRPSFEPPPTTIAAVPPYIGPDTPALRTLSEYARPHVMSPTNR 716
Query: 1223 REP------PEEPGLSQEGAMLLSPEPPAKEVEARPPLSPER-APEHDLEVEPEPPMMLP 1275
P P +P L+ L + +P +E E R ER E +L +P +
Sbjct: 717 NHPFYMPLNPTDPLLAYHMPGLYNVDPTIRERELREREIREREIRERELRERMKPGFEVK 776
Query: 1276 LPLQPPLPPPRPPRPPSPPPEPETTDASHPSVPPEPLAEDHPPHTP 1321
P PL P P T P+ P P A HP P
Sbjct: 777 PPELDPLHPAANPMEHFARHSALTIP---PTAGPHPFASFHPGLNP 819
>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 103 bits (257), Expect = 2e-21
Identities = 161/597 (26%), Positives = 213/597 (35%), Gaps = 123/597 (20%)
Query: 1068 SDDRDESENDDEDTALSEASEKDEGDSDEEETVSIVTSKAEATSSSESSESSEFESSSES 1127
+D + E+ EAS + + + E V+ T +A+ TSS ++ E S +
Sbjct: 622 NDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQ---EISRPN 678
Query: 1128 SPSSSEDEEEVVAREEEEEEEEEEMVAEESMASAGPEDFEQDGEEAALAPGAPAVDSLGM 1187
SPS E E E + V +E S+ P+D +QD + P P+
Sbjct: 679 SPS-----------EGEGESSDSRSVNDEG--SSDPKDIDQDNRSTS--PSIPSPQ---- 719
Query: 1188 EEEVDIETEAVAPEERPSMLDEPPL---PVGVEEPADSREPPEEPGLSQEGAMLLSPEPP 1244
D E+++ + ++ + +PP P GV PA S PP P L G P P
Sbjct: 720 ----DNESDSDSSAQQQMLQAQPPALQAPTGVT-PAPSSAPPGTPQLPTPG-----PTPS 769
Query: 1245 AKEVEARPPLSPERAPEHDLEVEPEPPMMLPLPLQ--PPLPPPRPPRPPSPPPEPETTDA 1302
A V + + +AP +P+ P P+P P P RPPSP P P
Sbjct: 770 ATAVPPQGSPTASQAPN-----QPQAPTA-PVPHTHIQQAPALHPQRPPSPHPPP----- 818
Query: 1303 SHPSVPPEPLAEDHPPHTPGLCGSLAKSQSTETVPATPG-GEPPLSGGSSGLSLSSPQVP 1361
HPS HPP P L GS + P+ P +PPL G Q P
Sbjct: 819 -HPS--------PHPPLQP-LTGSAGQ-------PSAPSHAQPPLHG----------QGP 851
Query: 1362 GSPFSYPAPSPSLSSGGLPRTPGRDFSFTPTFSEPSGPLLLPVCPLPTGRRDERSGPLAS 1421
P S A P L G P + F P S+ PL P P +
Sbjct: 852 PGPHSLQA-GPLLQHPG----PPQPFGLPPQASQGQAPL--GTSPAAAYPHTSLQLPASQ 904
Query: 1422 PVLLETGLPLPLPLPLPLPLALPAVLRAQARAPTPLPPLLPAPLASCPPPMKRKPGR--- 1478
L P PLP P PLA+P + PT P LPAP A PP P
Sbjct: 905 SALQSQQPPREQPLP-PAPLAMPHI----KPPPTTPIPQLPAPQAHKHPPHLSGPSPFSM 959
Query: 1479 -------PRRSPPSMLSLDGPLVRPPAGAALGRELLLLPGQPQTPVF----------PST 1521
P P S LS P P L + LP P P P++
Sbjct: 960 NANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPAS 1019
Query: 1522 HDPRTVTLDFRNAGIPAPPPPLPPQPPPPPPPPPVEPTKLPFKELDNQWPSEAIPPGPRG 1581
H P + AP PP P P PPP+ P P P + P G
Sbjct: 1020 HPPTGLHQ-------VAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSG 1072
Query: 1582 RDEVTEEYMELAKSRGPWRRPPKKRHEDLVPPAGSPELSPPQPLFRPRSEFEEMTIL 1638
S P P + E+ + A PE SPP P PRS E T++
Sbjct: 1073 --AAASGGSIAGGSSCP--LPTVQIKEEALDDAEEPE-SPPPP---PRSPSPEPTVV 1121
Score = 83.2 bits (204), Expect = 2e-15
Identities = 132/535 (24%), Positives = 170/535 (31%), Gaps = 143/535 (26%)
Query: 362 GSSGPPFKAQPQDSATFAHTPPPAQATPAPGFKSAFSPYQTPVAHFPPPPEEPTATAAFG 421
GSS P K QD+ + + + P Q + SA Q + PP + PT
Sbjct: 697 GSSDP--KDIDQDNRSTSPSIPSPQDNESDSDSSA---QQQMLQAQPPALQAPTGVT--- 748
Query: 422 ARDSGEFRRAPAPPPLPPAEPLAKEKPGTPPGPPPPDTNSMELGGRPTFGWSPEPCDSPG 481
PAP PP P PGP P T ++ G PT +P +P
Sbjct: 749 ----------PAPSSAPPGTPQLPT-----PGPTPSAT-AVPPQGSPTASQAPNQPQAPT 792
Query: 482 TPT----LESSPA----GPEKPHDSLDSRIEMLLKEQRTKLLFLREPDSDTELQMEGSPI 533
P ++ +PA P PH P LQ P+
Sbjct: 793 APVPHTHIQQAPALHPQRPPSPHPP-------------------PHPSPHPPLQ----PL 829
Query: 534 SSSSSQLSPLAPFGTNSQPGFRGPTPPSSRPSSTGLEDISPTPLPDSDEDEELDLGLGPR 593
+ S+ Q P AP +++QP G PP G PL
Sbjct: 830 TGSAGQ--PSAP--SHAQPPLHGQGPPGPHSLQAG-------PLLQ-------------- 864
Query: 594 PPPEPGPPDPAGLLSQTAEVALDL----VGDRTPTSEKMDEGQQSSGEDMEISDDEMPSA 649
PGPP P GL Q ++ L TS ++ Q + + +P A
Sbjct: 865 ---HPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPA 921
Query: 650 PITSADC------PKPMVVTPGAAA----VAAPSVLAPTLPLPPPPGFPPLP------PP 693
P+ P P + P A ++ PS + LPPPP PL PP
Sbjct: 922 PLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPP 981
Query: 694 PPPPPPQPGFPMPPPLPPPPPPPPPAHPAVTVPPPPLPAPPG-----VPPPPILPPLPPF 748
PPP P PLP P PP + +PPPP PP P PP PF
Sbjct: 982 SAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQ--HPF 1039
Query: 749 PPGLFPVMQVDMSHVLGGQWGGMPMSFQMQTQVLSRLMTGQGACPYPPFMAAAAAAAS-A 807
P GG P S G G PP AAA+ S A
Sbjct: 1040 VP------------------GGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIA 1081
Query: 808 GLQFVNLPPYRGPFSLSNSGPGRGQHWPPLPKFDPSVPPPGYMPRQEDPHKATVD 862
G LP + + +P PPP PR P VD
Sbjct: 1082 GGSSCPLPTVQIKEEALDDAE------------EPESPPP--PPRSPSPEPTVVD 1122
Score = 68.9 bits (167), Expect = 4e-11
Identities = 108/435 (24%), Positives = 147/435 (33%), Gaps = 106/435 (24%)
Query: 445 KEKPGTPPGPPPPDTNSMELGGRPTFGWSPEPCDSPGTPTLESSPAGPEKPHDSLDSRIE 504
K++P +P G P + GR +SP + S+ DS+ E
Sbjct: 589 KKQPASPDGRTSPINEDIRSSGR----------NSPSAASTSSN-----------DSKAE 627
Query: 505 MLLKEQRTKLLFLREPDSDTELQMEGSPISSSSSQLSPLAPFGTNSQPGFRGPTPPSSRP 564
+ K + ++E S SP+ S+ Q +A T + R
Sbjct: 628 TVKKSAKK----VKEEAS--------SPLKSNKRQREKVA-----------SDTEEADRT 664
Query: 565 SS--TGLEDISPTPLPDSDEDEELDLGLGPRPPPEPGPPDPAGLLSQTAEVALDLVGDRT 622
SS T ++IS P E E D R + G DP D+ D
Sbjct: 665 SSKKTKTQEISRPNSPSEGEGESSD----SRSVNDEGSSDPK-----------DIDQDNR 709
Query: 623 PTSEKMDEGQQSSGEDMEISDDEMPSAPITSADCPKPMVVTPGAAAVAAPSVLAPTLPLP 682
TS + Q + + + +M A + P + P +A P + P P P
Sbjct: 710 STSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPG-PTP 768
Query: 683 -----PPPGFPPL------PPPPPPPPPQPGFPMPPPLPP--PPPPPPPAHPAVTVPPPP 729
PP G P P P P P P L P PP P PP HP+ P P
Sbjct: 769 SATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQP 828
Query: 730 LPAPPGVPPPP--ILPPL----PPFPPGLF--PVMQVDMSHVLGGQWGGMPMSFQMQTQV 781
L G P P PPL PP P L P++Q G P F + Q
Sbjct: 829 LTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHP----------GPPQPFGLPPQA 878
Query: 782 LSRLMTGQGACPYPPFMAAAAAAASAGLQFVNLPPYRGPFSLSNSGPGRGQHWPPLPKFD 841
QG P AAA S + LP + +L + P R Q PP P
Sbjct: 879 ------SQGQAPLGTSPAAAYPHTS-----LQLPASQS--ALQSQQPPREQPLPPAPLAM 925
Query: 842 PSVPPPGYMPRQEDP 856
P + PP P + P
Sbjct: 926 PHIKPPPTTPIPQLP 940
Score = 60.1 bits (144), Expect = 2e-08
Identities = 97/396 (24%), Positives = 123/396 (31%), Gaps = 72/396 (18%)
Query: 384 PAQATPAPGFKSAFSPYQTPVAHFPPPPEEPTATAAFGARDSGEFRRAPAPPPLPPAEPL 443
PA ++ PG +P TP A PP PTA+ A + + AP P +
Sbjct: 749 PAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQA-----PNQPQAPTAPVPHTHIQQA 803
Query: 444 AKEKPGTPPGPPPPDTNSMELGGRPTFGWSPEP-CDSPGTPTLESSPAGPEKPHDSLDSR 502
P PP P PP S +P G + +P S P L GP PH +
Sbjct: 804 PALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQ--GPPGPHSL---Q 858
Query: 503 IEMLLKEQRTKLLFLREPD-SDTELQMEGSPISS---SSSQLSPLAPFGTNSQPGFRGPT 558
LL+ F P S + + SP ++ +S QL + QP P
Sbjct: 859 AGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPL 918
Query: 559 PPSSRPSSTGLEDISP---TPLPDSDEDEELDLGLGPRPPPEPGPPDP----AGLLSQTA 611
PP+ + I P TP+P +L + PP P P A L A
Sbjct: 919 PPAP----LAMPHIKPPPTTPIP------QLPAPQAHKHPPHLSGPSPFSMNANLPPPPA 968
Query: 612 EVALDLVGDRTPTSEKMDEGQQSSGEDMEISDDEMPSAPITSADCPKPMVVTPGAA---- 667
L + P S Q S P S + P P P
Sbjct: 969 LKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQV 1028
Query: 668 AVAAPSVLAPTLPLPPPPGFPPLPPPPPPPPPQPGFPMPPPL------------------ 709
A P P +P PPP PP P PP PG PP
Sbjct: 1029 APQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPL 1088
Query: 710 ------------------PPPPPPPPPAHPAVTVPP 727
PPPPP P P V P
Sbjct: 1089 PTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTP 1124
Score = 39.7 bits (91), Expect = 0.029
Identities = 25/94 (26%), Positives = 41/94 (43%), Gaps = 5/94 (5%)
Query: 989 EEDEESERERDRDMADTPCELAKRDPKGVGVRRRPARPLELDSGGEEDEKESLSEEQEST 1048
++D+E +R+RDRD E KRD RP R L+ G + + SE++++
Sbjct: 8 DKDKEKDRDRDRDR-----EREKRDKARESENSRPRRSCTLEGGAKNYAESDHSEDEDND 62
Query: 1049 EEEEEAEEEEEEEDDDDDDSDDRDESENDDEDTA 1082
AEE ++ R E + E T+
Sbjct: 63 NNSATAEESTKKNKKKPPKKKSRYERTDTGEITS 96
Score = 33.9 bits (76), Expect = 1.6
Identities = 52/226 (23%), Positives = 78/226 (34%), Gaps = 32/226 (14%)
Query: 1119 SEFESSSESSPSSSEDEEEVVAREEEEEEEEEEMVAEESMASAGPEDFEQDGEEAALAPG 1178
S+ E + ++ E E AREE E E+E+E E + E++ E AA A
Sbjct: 1157 SKLAKKREEAIEKAKREAEQKAREEREREKEKEKERERE------REREREAERAAKASS 1210
Query: 1179 APAVDSLGMEEEVDIETEAVAPEERPSMLDEPPLPVGVEEPA----------------DS 1222
+ L + + E P+ + P +G + PA +
Sbjct: 1211 SAHEGRLSDPQLSGPGHMRPSFEPPPTTIAAVPPYIGPDTPALRTLSEYARPHVMSPTNR 1270
Query: 1223 REP------PEEPGLSQEGAMLLSPEPPAKEVEARPPLSPER-APEHDLEVEPEPPMMLP 1275
P P +P L+ L + +P +E E R ER E +L +P +
Sbjct: 1271 NHPFYMPLNPTDPLLAYHMPGLYNVDPTIRERELREREIREREIRERELRERMKPGFEVK 1330
Query: 1276 LPLQPPLPPPRPPRPPSPPPEPETTDASHPSVPPEPLAEDHPPHTP 1321
P PL P P T P+ P P A HP P
Sbjct: 1331 PPELDPLHPAANPMEHFARHSALTIP---PTAGPHPFASFHPGLNP 1373
>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 103 bits (257), Expect = 2e-21
Identities = 161/597 (26%), Positives = 213/597 (35%), Gaps = 123/597 (20%)
Query: 1068 SDDRDESENDDEDTALSEASEKDEGDSDEEETVSIVTSKAEATSSSESSESSEFESSSES 1127
+D + E+ EAS + + + E V+ T +A+ TSS ++ E S +
Sbjct: 622 NDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQ---EISRPN 678
Query: 1128 SPSSSEDEEEVVAREEEEEEEEEEMVAEESMASAGPEDFEQDGEEAALAPGAPAVDSLGM 1187
SPS E E E + V +E S+ P+D +QD + P P+
Sbjct: 679 SPS-----------EGEGESSDSRSVNDEG--SSDPKDIDQDNRSTS--PSIPSPQ---- 719
Query: 1188 EEEVDIETEAVAPEERPSMLDEPPL---PVGVEEPADSREPPEEPGLSQEGAMLLSPEPP 1244
D E+++ + ++ + +PP P GV PA S PP P L G P P
Sbjct: 720 ----DNESDSDSSAQQQMLQAQPPALQAPTGVT-PAPSSAPPGTPQLPTPG-----PTPS 769
Query: 1245 AKEVEARPPLSPERAPEHDLEVEPEPPMMLPLPLQ--PPLPPPRPPRPPSPPPEPETTDA 1302
A V + + +AP +P+ P P+P P P RPPSP P P
Sbjct: 770 ATAVPPQGSPTASQAPN-----QPQAPTA-PVPHTHIQQAPALHPQRPPSPHPPP----- 818
Query: 1303 SHPSVPPEPLAEDHPPHTPGLCGSLAKSQSTETVPATPG-GEPPLSGGSSGLSLSSPQVP 1361
HPS HPP P L GS + P+ P +PPL G Q P
Sbjct: 819 -HPS--------PHPPLQP-LTGSAGQ-------PSAPSHAQPPLHG----------QGP 851
Query: 1362 GSPFSYPAPSPSLSSGGLPRTPGRDFSFTPTFSEPSGPLLLPVCPLPTGRRDERSGPLAS 1421
P S A P L G P + F P S+ PL P P +
Sbjct: 852 PGPHSLQA-GPLLQHPG----PPQPFGLPPQASQGQAPL--GTSPAAAYPHTSLQLPASQ 904
Query: 1422 PVLLETGLPLPLPLPLPLPLALPAVLRAQARAPTPLPPLLPAPLASCPPPMKRKPGR--- 1478
L P PLP P PLA+P + PT P LPAP A PP P
Sbjct: 905 SALQSQQPPREQPLP-PAPLAMPHI----KPPPTTPIPQLPAPQAHKHPPHLSGPSPFSM 959
Query: 1479 -------PRRSPPSMLSLDGPLVRPPAGAALGRELLLLPGQPQTPVF----------PST 1521
P P S LS P P L + LP P P P++
Sbjct: 960 NANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPAS 1019
Query: 1522 HDPRTVTLDFRNAGIPAPPPPLPPQPPPPPPPPPVEPTKLPFKELDNQWPSEAIPPGPRG 1581
H P + AP PP P P PPP+ P P P + P G
Sbjct: 1020 HPPTGLHQ-------VAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSG 1072
Query: 1582 RDEVTEEYMELAKSRGPWRRPPKKRHEDLVPPAGSPELSPPQPLFRPRSEFEEMTIL 1638
S P P + E+ + A PE SPP P PRS E T++
Sbjct: 1073 --AAASGGSIAGGSSCP--LPTVQIKEEALDDAEEPE-SPPPP---PRSPSPEPTVV 1121
Score = 83.2 bits (204), Expect = 2e-15
Identities = 132/535 (24%), Positives = 170/535 (31%), Gaps = 143/535 (26%)
Query: 362 GSSGPPFKAQPQDSATFAHTPPPAQATPAPGFKSAFSPYQTPVAHFPPPPEEPTATAAFG 421
GSS P K QD+ + + + P Q + SA Q + PP + PT
Sbjct: 697 GSSDP--KDIDQDNRSTSPSIPSPQDNESDSDSSA---QQQMLQAQPPALQAPTGVT--- 748
Query: 422 ARDSGEFRRAPAPPPLPPAEPLAKEKPGTPPGPPPPDTNSMELGGRPTFGWSPEPCDSPG 481
PAP PP P PGP P T ++ G PT +P +P
Sbjct: 749 ----------PAPSSAPPGTPQLPT-----PGPTPSAT-AVPPQGSPTASQAPNQPQAPT 792
Query: 482 TPT----LESSPA----GPEKPHDSLDSRIEMLLKEQRTKLLFLREPDSDTELQMEGSPI 533
P ++ +PA P PH P LQ P+
Sbjct: 793 APVPHTHIQQAPALHPQRPPSPHPP-------------------PHPSPHPPLQ----PL 829
Query: 534 SSSSSQLSPLAPFGTNSQPGFRGPTPPSSRPSSTGLEDISPTPLPDSDEDEELDLGLGPR 593
+ S+ Q P AP +++QP G PP G PL
Sbjct: 830 TGSAGQ--PSAP--SHAQPPLHGQGPPGPHSLQAG-------PLLQ-------------- 864
Query: 594 PPPEPGPPDPAGLLSQTAEVALDL----VGDRTPTSEKMDEGQQSSGEDMEISDDEMPSA 649
PGPP P GL Q ++ L TS ++ Q + + +P A
Sbjct: 865 ---HPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPA 921
Query: 650 PITSADC------PKPMVVTPGAAA----VAAPSVLAPTLPLPPPPGFPPLP------PP 693
P+ P P + P A ++ PS + LPPPP PL PP
Sbjct: 922 PLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPP 981
Query: 694 PPPPPPQPGFPMPPPLPPPPPPPPPAHPAVTVPPPPLPAPPG-----VPPPPILPPLPPF 748
PPP P PLP P PP + +PPPP PP P PP PF
Sbjct: 982 SAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQ--HPF 1039
Query: 749 PPGLFPVMQVDMSHVLGGQWGGMPMSFQMQTQVLSRLMTGQGACPYPPFMAAAAAAAS-A 807
P GG P S G G PP AAA+ S A
Sbjct: 1040 VP------------------GGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIA 1081
Query: 808 GLQFVNLPPYRGPFSLSNSGPGRGQHWPPLPKFDPSVPPPGYMPRQEDPHKATVD 862
G LP + + +P PPP PR P VD
Sbjct: 1082 GGSSCPLPTVQIKEEALDDAE------------EPESPPP--PPRSPSPEPTVVD 1122
Score = 68.9 bits (167), Expect = 4e-11
Identities = 108/435 (24%), Positives = 147/435 (33%), Gaps = 106/435 (24%)
Query: 445 KEKPGTPPGPPPPDTNSMELGGRPTFGWSPEPCDSPGTPTLESSPAGPEKPHDSLDSRIE 504
K++P +P G P + GR +SP + S+ DS+ E
Sbjct: 589 KKQPASPDGRTSPINEDIRSSGR----------NSPSAASTSSN-----------DSKAE 627
Query: 505 MLLKEQRTKLLFLREPDSDTELQMEGSPISSSSSQLSPLAPFGTNSQPGFRGPTPPSSRP 564
+ K + ++E S SP+ S+ Q +A T + R
Sbjct: 628 TVKKSAKK----VKEEAS--------SPLKSNKRQREKVA-----------SDTEEADRT 664
Query: 565 SS--TGLEDISPTPLPDSDEDEELDLGLGPRPPPEPGPPDPAGLLSQTAEVALDLVGDRT 622
SS T ++IS P E E D R + G DP D+ D
Sbjct: 665 SSKKTKTQEISRPNSPSEGEGESSD----SRSVNDEGSSDPK-----------DIDQDNR 709
Query: 623 PTSEKMDEGQQSSGEDMEISDDEMPSAPITSADCPKPMVVTPGAAAVAAPSVLAPTLPLP 682
TS + Q + + + +M A + P + P +A P + P P P
Sbjct: 710 STSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPG-PTP 768
Query: 683 -----PPPGFPPL------PPPPPPPPPQPGFPMPPPLPP--PPPPPPPAHPAVTVPPPP 729
PP G P P P P P P L P PP P PP HP+ P P
Sbjct: 769 SATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQP 828
Query: 730 LPAPPGVPPPP--ILPPL----PPFPPGLF--PVMQVDMSHVLGGQWGGMPMSFQMQTQV 781
L G P P PPL PP P L P++Q G P F + Q
Sbjct: 829 LTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHP----------GPPQPFGLPPQA 878
Query: 782 LSRLMTGQGACPYPPFMAAAAAAASAGLQFVNLPPYRGPFSLSNSGPGRGQHWPPLPKFD 841
QG P AAA S + LP + +L + P R Q PP P
Sbjct: 879 ------SQGQAPLGTSPAAAYPHTS-----LQLPASQS--ALQSQQPPREQPLPPAPLAM 925
Query: 842 PSVPPPGYMPRQEDP 856
P + PP P + P
Sbjct: 926 PHIKPPPTTPIPQLP 940
Score = 60.1 bits (144), Expect = 2e-08
Identities = 97/396 (24%), Positives = 123/396 (31%), Gaps = 72/396 (18%)
Query: 384 PAQATPAPGFKSAFSPYQTPVAHFPPPPEEPTATAAFGARDSGEFRRAPAPPPLPPAEPL 443
PA ++ PG +P TP A PP PTA+ A + + AP P +
Sbjct: 749 PAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQA-----PNQPQAPTAPVPHTHIQQA 803
Query: 444 AKEKPGTPPGPPPPDTNSMELGGRPTFGWSPEP-CDSPGTPTLESSPAGPEKPHDSLDSR 502
P PP P PP S +P G + +P S P L GP PH +
Sbjct: 804 PALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQ--GPPGPHSL---Q 858
Query: 503 IEMLLKEQRTKLLFLREPD-SDTELQMEGSPISS---SSSQLSPLAPFGTNSQPGFRGPT 558
LL+ F P S + + SP ++ +S QL + QP P
Sbjct: 859 AGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPL 918
Query: 559 PPSSRPSSTGLEDISP---TPLPDSDEDEELDLGLGPRPPPEPGPPDP----AGLLSQTA 611
PP+ + I P TP+P +L + PP P P A L A
Sbjct: 919 PPAP----LAMPHIKPPPTTPIP------QLPAPQAHKHPPHLSGPSPFSMNANLPPPPA 968
Query: 612 EVALDLVGDRTPTSEKMDEGQQSSGEDMEISDDEMPSAPITSADCPKPMVVTPGAA---- 667
L + P S Q S P S + P P P
Sbjct: 969 LKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQV 1028
Query: 668 AVAAPSVLAPTLPLPPPPGFPPLPPPPPPPPPQPGFPMPPPL------------------ 709
A P P +P PPP PP P PP PG PP
Sbjct: 1029 APQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPL 1088
Query: 710 ------------------PPPPPPPPPAHPAVTVPP 727
PPPPP P P V P
Sbjct: 1089 PTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTP 1124
Score = 39.7 bits (91), Expect = 0.029
Identities = 25/94 (26%), Positives = 41/94 (43%), Gaps = 5/94 (5%)
Query: 989 EEDEESERERDRDMADTPCELAKRDPKGVGVRRRPARPLELDSGGEEDEKESLSEEQEST 1048
++D+E +R+RDRD E KRD RP R L+ G + + SE++++
Sbjct: 8 DKDKEKDRDRDRDR-----EREKRDKARESENSRPRRSCTLEGGAKNYAESDHSEDEDND 62
Query: 1049 EEEEEAEEEEEEEDDDDDDSDDRDESENDDEDTA 1082
AEE ++ R E + E T+
Sbjct: 63 NNSATAEESTKKNKKKPPKKKSRYERTDTGEITS 96
Score = 33.9 bits (76), Expect = 1.6
Identities = 52/226 (23%), Positives = 78/226 (34%), Gaps = 32/226 (14%)
Query: 1119 SEFESSSESSPSSSEDEEEVVAREEEEEEEEEEMVAEESMASAGPEDFEQDGEEAALAPG 1178
S+ E + ++ E E AREE E E+E+E E + E++ E AA A
Sbjct: 1157 SKLAKKREEAIEKAKREAEQKAREEREREKEKEKERERE------REREREAERAAKASS 1210
Query: 1179 APAVDSLGMEEEVDIETEAVAPEERPSMLDEPPLPVGVEEPA----------------DS 1222
+ L + + E P+ + P +G + PA +
Sbjct: 1211 SAHEGRLSDPQLSGPGHMRPSFEPPPTTIAAVPPYIGPDTPALRTLSEYARPHVMSPTNR 1270
Query: 1223 REP------PEEPGLSQEGAMLLSPEPPAKEVEARPPLSPER-APEHDLEVEPEPPMMLP 1275
P P +P L+ L + +P +E E R ER E +L +P +
Sbjct: 1271 NHPFYMPLNPTDPLLAYHMPGLYNVDPTIRERELREREIREREIRERELRERMKPGFEVK 1330
Query: 1276 LPLQPPLPPPRPPRPPSPPPEPETTDASHPSVPPEPLAEDHPPHTP 1321
P PL P P T P+ P P A HP P
Sbjct: 1331 PPELDPLHPAANPMEHFARHSALTIP---PTAGPHPFASFHPGLNP 1373
>gi|7706501 WW domain binding protein 11 [Homo sapiens]
Length = 641
Score = 103 bits (257), Expect = 2e-21
Identities = 108/418 (25%), Positives = 159/418 (38%), Gaps = 79/418 (18%)
Query: 386 QATPAPGFKSAFSPYQTPVAHFPPPPEEPTA----TAAFGARDSGEFRRAPAPPPL---- 437
++ P P A P + P P +P + T+A+G RA + PL
Sbjct: 137 ESIPLPDMPHA--PSNILIQDIPLPGAQPPSILKKTSAYGPPT-----RAVSILPLLGHG 189
Query: 438 PPAEPLAKEKPGTPPGPPPPDTNSMELGGRPTFG-------------WSPEPCDSPGTPT 484
P P ++ PG PPGPPPP M G + F +SPE
Sbjct: 190 VPRLPPGRKPPGPPPGPPPPQVVQM-YGRKVGFALDLPPRRRDEDMLYSPELAQRGHDDD 248
Query: 485 LESSPAGPEKPHDSLDSRIEMLLKEQRTKLLFLREPDSDTELQMEGSPISSSSSQLSPLA 544
+ S+ P D + + + T E D D + + ++ + S L+
Sbjct: 249 VSSTSEDDGYPEDMDQDKHDDSTDDSDTDKSD-GESDGDEFVHRDNGERDNNEEKKSGLS 307
Query: 545 PFGTNSQPGFRGPTPPSSRPSSTGLEDISPTPLPDSDEDEELDLGLGPRPPPEPGPPDPA 604
+ P SR +++++P + + L + + PE G
Sbjct: 308 VRFADM--------PGKSRKKKKNMKELTPL--------QAMMLRMAGQEIPEEGREVEE 351
Query: 605 GLLSQTAEVALDLVGDRTPTSEKMDE----GQQSSGEDMEISDDEMPSAPITSADCPKPM 660
+ + D ++ + +E G ++ + +P + I + P P
Sbjct: 352 FSEDDDEDDSDDSEAEKQSQKQHKEESHSDGTSTASSQQQAPPQSVPPSQIQAPPMPGPP 411
Query: 661 VVTPGAAAVAAPSVLAPTLPLPPPPGFPPL--PP-------------PPPPPPPQPGFPM 705
+ P A P LP PPPG PP PP PP PPP +P P
Sbjct: 412 PLGPPPAPPLRPPGPPTGLPPGPPPGAPPFLRPPGMPGLRGPLPRLLPPGPPPGRP--PG 469
Query: 706 PPPLPPP--PPPPPPAHPAVTVPPPPLPAPPGVPP-------PPILPPLPPFPPGLFP 754
PPP PPP PP PPP P +PP PAPPG+PP PP++PPL P PPGLFP
Sbjct: 470 PPPGPPPGLPPGPPPRGPPPRLPP---PAPPGIPPPRPGMMRPPLVPPLGPAPPGLFP 524
Score = 84.7 bits (208), Expect = 8e-16
Identities = 111/450 (24%), Positives = 153/450 (34%), Gaps = 104/450 (23%)
Query: 996 RERDRDMADTPCELAKRDPKGVGVRRRPARPLELDSGGEEDEKESLSEEQESTEEEEEAE 1055
R RD DM +P ELA+R G +D+ S SE+ E+ ++ +
Sbjct: 228 RRRDEDMLYSP-ELAQR--------------------GHDDDVSSTSEDDGYPEDMDQDK 266
Query: 1056 EEEEEEDDDDDDSDD---------RDESENDDEDTALSEAS-----------EKDEGDSD 1095
++ +D D D SD RD E D+ + S S +K + +
Sbjct: 267 HDDSTDDSDTDKSDGESDGDEFVHRDNGERDNNEEKKSGLSVRFADMPGKSRKKKKNMKE 326
Query: 1096 EEETVSIVTSKAEATSSSESSESSEFESSSESSPSSSEDEEEVVAREEEEEEEEEEMVAE 1155
+++ A E E EF + S + E+ ++ +EE +
Sbjct: 327 LTPLQAMMLRMAGQEIPEEGREVEEFSEDDDEDDSDDSEAEKQSQKQHKEESHSDGTSTA 386
Query: 1156 ESMASAGPEDFEQDGEEAALAPGAPAVDSLGMEEEVDIETEAVAPEERPSMLDEPP--LP 1213
S A P+ +A PG P + AP RP PP LP
Sbjct: 387 SSQQQAPPQSVPPSQIQAPPMPGPPPLGP------------PPAPPLRPP---GPPTGLP 431
Query: 1214 VGVEEPADS-REPPEEPGLSQEGAMLLSPEPPAKEVEARPPLSPERAPEHDLEVEPEPPM 1272
G A PP PGL LL P PP RPP P P PP
Sbjct: 432 PGPPPGAPPFLRPPGMPGLRGPLPRLLPPGPPP----GRPPGPP-----------PGPP- 475
Query: 1273 MLPLPLQPPLPPPRPPRPPSPPPEPETTDASHPSVPPEPLAEDHPPHTPGLCGSLAKSQS 1332
P PP PPPR P P PPP P P +PP PP P L
Sbjct: 476 ----PGLPPGPPPRGPPPRLPPPAP-------PGIPPPRPGMMRPPLVPPL--------- 515
Query: 1333 TETVPATPGGEPPLSGGSSGLSLSSPQVPGSPFSYPAPSPSLSSGGLPRTPGRDFSFTPT 1392
PA PG PP + G+ + P + P + S+ + + S P
Sbjct: 516 ---GPAPPGLFPPAPLPNPGVLSAPPNLIQRP-----KADDTSAATIEKKATATISAKPQ 567
Query: 1393 FSEPSGPLLLPVCPLPTGRRDERSGPLASP 1422
+ P + V P R E G A+P
Sbjct: 568 ITNPKAEITRFV-PTALRVRRENKGATAAP 596
Score = 80.9 bits (198), Expect = 1e-14
Identities = 96/372 (25%), Positives = 138/372 (37%), Gaps = 59/372 (15%)
Query: 1021 RRPARPLELDSGGEEDEKESLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDESENDDED 1080
R+ L+L +++ E + +++ + E++ +D D D D+S DD D
Sbjct: 217 RKVGFALDLPPRRRDEDMLYSPELAQRGHDDDVSSTSEDDGYPEDMDQDKHDDS-TDDSD 275
Query: 1081 TALSEASEKDEGDSDEEETVSIVTSKAEATSSSESSESSEFESSSESSPSSSEDEEE--- 1137
T +K +G+SD +E V + + +S S F S ++ +E
Sbjct: 276 T------DKSDGESDGDEFVHRDNGERDNNEEKKSGLSVRFADMPGKSRKKKKNMKELTP 329
Query: 1138 ---VVAREEEEEEEEEEMVAEESMASAGPEDFEQDGEEAALAPGAPAVDSLGMEEEVDIE 1194
++ R +E EE EE S ++ + D EA + +
Sbjct: 330 LQAMMLRMAGQEIPEEGREVEE--FSEDDDEDDSDDSEAEKQSQKQHKEESHSDGTSTAS 387
Query: 1195 TEAVAPEER--PSMLDEPPLPVGVEEPADSREPPEEPGLSQEGAMLLSPEPPAKEVEARP 1252
++ AP + PS + PP+P P PP P L P PP P
Sbjct: 388 SQQQAPPQSVPPSQIQAPPMP----GPPPLGPPPAPP--------LRPPGPPT----GLP 431
Query: 1253 PLSPERAPEHDLEVEPEPPMMLPLP-LQPPLPPPRPPRPPSPPPEPETTDASHPSVPPEP 1311
P P AP L P + PLP L PP PP P RPP PPP P P +PP P
Sbjct: 432 PGPPPGAPPF-LRPPGMPGLRGPLPRLLPPGPP--PGRPPGPPPGPP------PGLPPGP 482
Query: 1312 LAEDHPPHTPGLCGSLAKSQSTETVPATPGGEPPLSGGSSGLSLSSPQVPGSPFSYPAPS 1371
PP P P P G PP G L P P P +P P+
Sbjct: 483 PPRGPPPRLP---------------PPAPPGIPPPRPGMMRPPLVPPLGPAPPGLFP-PA 526
Query: 1372 PSLSSGGLPRTP 1383
P + G L P
Sbjct: 527 PLPNPGVLSAPP 538
Score = 63.5 bits (153), Expect = 2e-09
Identities = 64/185 (34%), Positives = 70/185 (37%), Gaps = 58/185 (31%)
Query: 1449 AQARAPTPLPPLLPAPLASCPPPMKRKPGRPRRSPPSMLSLDGPLVRPPAGAALGREL-- 1506
+Q +AP P+P P PL P P R PG P PP P +RPP L L
Sbjct: 400 SQIQAP-PMPG--PPPLGPPPAPPLRPPGPPTGLPPGPPPGAPPFLRPPGMPGLRGPLPR 456
Query: 1507 LLLPGQPQ-TPVFPSTHDPRTVTLDFRNAGIPAPPPPLPPQPPPPPPPPPVEPTKLPFKE 1565
LL PG P P P P PPP LPP PPP PPP +LP
Sbjct: 457 LLPPGPPPGRPPGPP----------------PGPPPGLPPGPPPRGPPP-----RLP--- 492
Query: 1566 LDNQWPSEAIPPGPRGRDEVTEEYMELAKSRGPWRRPPKKRHEDLVPPAG--SPELSPPQ 1623
PP P G + R RPP LVPP G P L PP
Sbjct: 493 ----------PPAPPG----------IPPPRPGMMRPP------LVPPLGPAPPGLFPPA 526
Query: 1624 PLFRP 1628
PL P
Sbjct: 527 PLPNP 531
Score = 55.5 bits (132), Expect = 5e-07
Identities = 61/223 (27%), Positives = 70/223 (31%), Gaps = 56/223 (25%)
Query: 525 ELQMEGSPISSSSSQLSPLA-PFGTNSQPGFRGPTPPSSRPSSTGLEDISPTPLPDSDED 583
E +G+ +SS Q P + P P GP P P+ PT LP
Sbjct: 377 ESHSDGTSTASSQQQAPPQSVPPSQIQAPPMPGPPPLGPPPAPPLRPPGPPTGLPP---- 432
Query: 584 EELDLGLGPRPPPEPGPPDPAGLLSQTAEVALDLVGDRTPTSEKMDEGQQSSGEDMEISD 643
G P PP PP GL +
Sbjct: 433 -----GPPPGAPPFLRPPGMPGLRGPLPRL------------------------------ 457
Query: 644 DEMPSAPITSADCPKPMVVTPGAAAVAAPSVLAPTLPLPPPPGFPPLPPPPPPPPPQPGF 703
+P P P PG P P LP P PPG PPP+PG
Sbjct: 458 --LPPGPPPGRPPGPPPGPPPGLPPGPPPRGPPPRLPPPAPPGI---------PPPRPGM 506
Query: 704 PMPPPLPPPPPPPPPAHPAVTVPPPPLPAPPGVPPPPILPPLP 746
M PPL PP P PP PP PLP P + PP L P
Sbjct: 507 -MRPPLVPPLGPAPPG----LFPPAPLPNPGVLSAPPNLIQRP 544
Score = 43.5 bits (101), Expect = 0.002
Identities = 35/109 (32%), Positives = 40/109 (36%), Gaps = 9/109 (8%)
Query: 1521 THDPRTVTLDFRNAGIPAPPPPLPPQPPPPPPPPPVEPTKLPFKELDNQWPSEAIPPGPR 1580
+H T T + P PP Q PP P PPP+ P P L P +PPGP
Sbjct: 378 SHSDGTSTASSQQQAPPQSVPPSQIQAPPMPGPPPLGPPPAP--PLRPPGPPTGLPPGPP 435
Query: 1581 GRDEVTEEYMELAKSRGPWRR-----PPKKRHEDLVPPAGSPELSPPQP 1624
+ RGP R PP R PP G P PP P
Sbjct: 436 PGAPPFLRPPGMPGLRGPLPRLLPPGPPPGRPPG--PPPGPPPGLPPGP 482
Score = 33.1 bits (74), Expect = 2.7
Identities = 23/61 (37%), Positives = 29/61 (47%), Gaps = 8/61 (13%)
Query: 1535 GIPA-PPPPLPPQPPPPPPPPPVEPTKLPFKELDNQWPSEAIPPGPRGRDEVTEEYMELA 1593
G+P PP PP PPP PPPP V ++ + A+ PR RDE ELA
Sbjct: 189 GVPRLPPGRKPPGPPPGPPPPQV-------VQMYGRKVGFALDLPPRRRDEDMLYSPELA 241
Query: 1594 K 1594
+
Sbjct: 242 Q 242
>gi|153792074 proline rich 12 [Homo sapiens]
Length = 2036
Score = 102 bits (255), Expect = 3e-21
Identities = 89/297 (29%), Positives = 113/297 (38%), Gaps = 52/297 (17%)
Query: 496 HDSLDSRIEMLLKEQRTKLLFLREPDSDTELQMEGSPISSSSSQLSPLAPFGTNSQPGFR 555
H+SLDS + E + K + ++P+ + S + PL Q G
Sbjct: 1251 HNSLDSSLTREKIEAKIKEVEEKQPEMKSGFMASFLDFLKSGKRHPPLY------QAGLT 1304
Query: 556 GP-TPPSSRPSSTGLEDISPTP-----LPDSDEDEELDLGLGPRPPPEP-----GPPDPA 604
P +PP S P S + P P +P LG G E G P P
Sbjct: 1305 PPLSPPKSVPPSVPARGLQPQPPATPAVPHPPPSGAFGLG-GALEAAESEGLGLGCPSPC 1363
Query: 605 GLLSQTAEVALDLV----GDRTPTSEKMDEGQQSSGEDMEISDDEM-------------P 647
L + + L+ + D + K + Q+S + DD P
Sbjct: 1364 KRLDEELKRNLETLPSFSSDEEDSVAKNRDLQESISSAISALDDPPLAGPKDTSTPDGPP 1423
Query: 648 SAPITSADCPKPMVVTPGAAAVAAPSVLAPTLPLPPPPGFPPLP-----PPPPPPPPQPG 702
AP + P P+ P A + P P L PPP PP P PPPPPPPPQP
Sbjct: 1424 LAPAAAVPGPPPLPGLPSANSNGTPE--PPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPA 1481
Query: 703 FPMPPPL----------PPPPPPPPPAHPAVTVPPPPLPAPPGVPPPPILPPLPPFP 749
P PPPL PP PPPPPPA P+ PPPP AP PP P P P
Sbjct: 1482 LPSPPPLVAPTPSSPPPPPLPPPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPSPEDP 1538
Score = 79.7 bits (195), Expect = 3e-14
Identities = 76/242 (31%), Positives = 94/242 (38%), Gaps = 52/242 (21%)
Query: 1120 EFESSSESSPSSSEDEEEVVAREEEEEEEEEEMV-AEESMASAGPEDFEQ-DGEEAALA- 1176
E + + E+ PS S DEE+ VA+ + +E + A + AGP+D DG A A
Sbjct: 1369 ELKRNLETLPSFSSDEEDSVAKNRDLQESISSAISALDDPPLAGPKDTSTPDGPPLAPAA 1428
Query: 1177 --------PGAPAVDSLGMEEEVDIETEAVAPEERPSMLDEPPLPVGVEEPADSREPPEE 1228
PG P+ +S G E P +L+E P P P +PP
Sbjct: 1429 AVPGPPPLPGLPSANSNGTPE--------------PPLLEEKPPPTPPPAPTPQPQPPPP 1474
Query: 1229 PGLSQEGAMLLSPEPPAKEVEARPPLSPERAPEHDLEVEPEPPMMLPLPLQPPLPPPRPP 1288
P PP + + PPL V P P P PL PP PPP P
Sbjct: 1475 P------------PPPQPALPSPPPL-----------VAPTPSSPPPPPLPPP-PPPAMP 1510
Query: 1289 RPPSPPPEPETTDASHPSVPPEPLAED-HPPHTPGLCGSLAKSQSTETVPATPGGEPPLS 1347
PP PPP A+ P P P ED P T L LAK Q T V E S
Sbjct: 1511 SPPPPPPPAAAPLAAPPEEPAAPSPEDPELPDTRPL--HLAKKQETAAVCGETDEEAGES 1568
Query: 1348 GG 1349
GG
Sbjct: 1569 GG 1570
Score = 69.3 bits (168), Expect = 3e-11
Identities = 93/341 (27%), Positives = 118/341 (34%), Gaps = 118/341 (34%)
Query: 430 RAPAPPPL------PPAEP---LAKEKPGTPPGPPPPDTNSMELGGRPTFGWS------- 473
+A PPL PP+ P L + P TP P PP + + LGG S
Sbjct: 1300 QAGLTPPLSPPKSVPPSVPARGLQPQPPATPAVPHPPPSGAFGLGGALEAAESEGLGLGC 1359
Query: 474 PEPC---DSPGTPTLESSPAGPEKPHDSLDSRIEMLLKEQRTKLLFLREPDSDTELQMEG 530
P PC D LE+ P+ DS+ ++ L + + + L +P
Sbjct: 1360 PSPCKRLDEELKRNLETLPSFSSDEEDSV-AKNRDLQESISSAISALDDPPL-------A 1411
Query: 531 SPISSSSSQLSPLAPF----GTNSQPGFRGPTPPSSRPSSTGLEDISPTPLPDSDEDEEL 586
P +S+ PLAP G PG P+ S+ L + P P P +
Sbjct: 1412 GPKDTSTPDGPPLAPAAAVPGPPPLPGL--PSANSNGTPEPPLLEEKPPPTPPPAPTPQ- 1468
Query: 587 DLGLGPRPPPEPGPPDPAGLLSQTAEVALDLVGDRTPTSEKMDEGQQSSGEDMEISDDEM 646
P+PPP P PP PA +
Sbjct: 1469 -----PQPPPPPPPPQPA-----------------------------------------L 1482
Query: 647 PSAPITSADCPKPMVVTPGAAAVAAPSVLAPTLPLPPPPGFPPLPPPPPPPPPQPGFPMP 706
PS P P+V AP+ +P PP PPLPPPPPP P
Sbjct: 1483 PS--------PPPLV---------APTPSSP----PP----PPLPPPPPPAMPS------ 1511
Query: 707 PPLPPPPPPPPPAHPAVTVPPPPLPAPPGVPPPPILPPLPP 747
PPPPPPP A P PP PA P P P LP P
Sbjct: 1512 ----PPPPPPPAAAPLAA--PPEEPAAPS-PEDPELPDTRP 1545
Score = 65.5 bits (158), Expect = 5e-10
Identities = 91/336 (27%), Positives = 110/336 (32%), Gaps = 89/336 (26%)
Query: 1271 PMMLPLPLQPPLPPPRPPRPPSPPPEPETTDASHPSVPPEPLAEDHPPHTPGLCGSLAKS 1330
P + L PPL PP+ PPS P + P+P A PH P
Sbjct: 1296 PPLYQAGLTPPLSPPKSV-PPSVPAR---------GLQPQPPATPAVPHPP--------- 1336
Query: 1331 QSTETVPATPGGEPPLSGGSSGLSLSSPQVPGSPFSYPAPSPSLSSGGLPRTPGRDFSFT 1390
P G L G +L + + G P+P L R+
Sbjct: 1337 ---------PSGAFGLGG-----ALEAAESEGLGLGCPSPCKRLDE-----ELKRNLETL 1377
Query: 1391 PTFSEPSGPLLLPVCPLPTGRRDERSG----PLASPVLLET--GLPLPLPLPLPLPLALP 1444
P+FS + L S PLA P T G PL +P P LP
Sbjct: 1378 PSFSSDEEDSVAKNRDLQESISSAISALDDPPLAGPKDTSTPDGPPLAPAAAVPGPPPLP 1437
Query: 1445 AVLRAQARAPTPLPPLLPAPLASCPPPMKRKPGRPRRSPPSMLSLDGPLVRPPAGAALGR 1504
+ A + TP PPLL PPP +P PP PP A
Sbjct: 1438 GLPSANSNG-TPEPPLLEEKPPPTPPPAPTPQPQPPPPPP-----------PPQPA---- 1481
Query: 1505 ELLLLPGQPQTPVFPSTHDPRTVTLDFRNAGIPAPPPPLPPQPPP----PPPPPPVEPTK 1560
LP P V P+ P PPPPLPP PPP PPPPPP P
Sbjct: 1482 ----LPSPPPL-VAPTPSSP--------------PPPPLPPPPPPAMPSPPPPPP--PAA 1520
Query: 1561 LPFKELDNQWPSEAIPPGPRGRDEVTEEYMELAKSR 1596
P P E P P + + LAK +
Sbjct: 1521 APLAAP----PEEPAAPSPEDPELPDTRPLHLAKKQ 1552
Score = 65.5 bits (158), Expect = 5e-10
Identities = 78/289 (26%), Positives = 98/289 (33%), Gaps = 53/289 (18%)
Query: 1243 PPAKEVEARPPLSPERAPEHDLEVEPEPPMMLPLPLQPPLPPPRPPRPPSPPPEPE-TTD 1301
PP + PPLSP ++ PP + LQP PP P P PPP
Sbjct: 1296 PPLYQAGLTPPLSPPKS---------VPPSVPARGLQP--QPPATPAVPHPPPSGAFGLG 1344
Query: 1302 ASHPSVPPEPLAEDHPPHTPGLCGSLAKSQSTETVPATPGGEPPLSGGSSGLSLSSPQVP 1361
+ + E L P L L ++ ET+P+ E + L S
Sbjct: 1345 GALEAAESEGLGLGCPSPCKRLDEEL--KRNLETLPSFSSDEEDSVAKNRDLQESISSAI 1402
Query: 1362 GSPFSYPAPSPSLSSGGLPRTPGRDFSFTPTFSEPSGPLLLPVC------PLPTGRRDER 1415
+ P P S P GP L P PLP
Sbjct: 1403 SALDDPPLAGPK------------------DTSTPDGPPLAPAAAVPGPPPLPGLPSANS 1444
Query: 1416 SGPLASPVLLETGLPLPLPLPLPLPLALPAVLRAQARAPTPLPPLLPAPLASCPPPMKRK 1475
+G P+L E P P P P P P P Q P+P P + P P + PPP+
Sbjct: 1445 NGTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPPPPPLPPP 1504
Query: 1476 PGRPRRSPPSMLSLDGPLVRPPAGAALGRELLLLPGQPQTPVFPSTHDP 1524
P PP+M S P PPA A L P+ P PS DP
Sbjct: 1505 P------PPAMPSPPPP--PPPAAAPLA-------APPEEPAAPSPEDP 1538
Score = 62.0 bits (149), Expect = 5e-09
Identities = 130/550 (23%), Positives = 171/550 (31%), Gaps = 108/550 (19%)
Query: 230 GGLSAGCGSGSSSVTPNSGGTPFSQDTAYSSCRLDTPNSYGQGTPLTPRLGTPFSQDSSY 289
GG +A +G +S +GG +S L P +YGQG S+ SY
Sbjct: 421 GGPAAAYATGKASGAGGAGGQAYSPGQPQG---LLGPQAYGQG--FGGGQAQDLSKAPSY 475
Query: 290 SSRQPTPSYLFSQDPAVTFKARRHESKFTDAYNRRHEHH---YVHN------SPAVTAVA 340
S P P T ++ + Y + E + H+ SP+++
Sbjct: 476 SGGPPQPPSGPPPPGLATCQSYSPDQLQGQLYGVQGEPYPGPAAHSQGLPTASPSLSYST 535
Query: 341 GATAAFRGSSDLPFGAVGGTGGSSGPPFKAQPQDSATFAHTPPPAQATPAPGFKSAFSPY 400
G + A G + G GG + P +P S PP + APG S
Sbjct: 536 GHSPALSGHGGGWGPSSLGGGGEASPSHIIRPLQSPPATGRPPGVGSPGAPG--KYLSSV 593
Query: 401 QTPVAHFPPPPEEPTATAAFGARDSGEFRRAPAPPPLPPAEPLAKEK---PGTPPGPPPP 457
PP A A G + G+ A P PPAE E+ P PP
Sbjct: 594 LASAPFLAPPGAGSYAAGAGGYKGKGDGSELLAGPGGPPAERTEDEEFLIQHLLQAPSPP 653
Query: 458 DTNSME--------LGGRPTFGWSPEPCDSPGTPTLESSPAGPEKPHDSLDSRIEMLLKE 509
T+ + G S PGTP E + P++ H R L E
Sbjct: 654 RTSGADGLVGEDGAADASKGLGGSGGAGGPPGTP-YELAKEDPQRYHLQSVIRTSASLDE 712
Query: 510 QRTKLLFLREPDSDTELQMEGSPISSSSSQLSPLAPFGTNSQPGFRGPTPPSSRPSSTGL 569
T L L L L + G G TP
Sbjct: 713 GATAALEL---------------------GLGRLKEKKKGPERG--GETP---------- 739
Query: 570 EDISPTPLPDSDEDEELDLGLGPRPPPEP-----GPPDPAGLLSQTAEVALDLVGDRTPT 624
E ++ + + +EL L PPP P P P GLL + L LV P
Sbjct: 740 EGLATSVVHYGAGAKELGAFLQKSPPPPPPTAQSTQPTPHGLLLEAGGPDLPLVLPPPPP 799
Query: 625 SEKMDEGQQSSGEDMEISDDEMPSAPITSADCPKPMVVTPGAAAVAAPSVLAPTLPLPPP 684
P + P P +P A+ V + T P
Sbjct: 800 Q----------------------LLPSVLSHAPSP---SPSASKVGVHLLEPATRDGAPQ 834
Query: 685 PGFPPLPPPPPPPPP------------QPGFPMPPPLPPPPPPPPPAHP---AVTVPPPP 729
P PP PPPPPPP P +P P P P PP A P PP
Sbjct: 835 P--PPPPPPPPPPMPLQLEAHLRSHGLEPAAPSPRLRPEESLDPPGAMQELLGALEPLPP 892
Query: 730 LPAPPGVPPP 739
P GV PP
Sbjct: 893 APGDTGVGPP 902
Score = 62.0 bits (149), Expect = 5e-09
Identities = 94/341 (27%), Positives = 122/341 (35%), Gaps = 46/341 (13%)
Query: 1230 GLSQEGAMLL-SPEPPAKEVEARPP-----LSPERAPEHDLEVEPEPPMMLPLPLQ-PPL 1282
G + GA L SP PP ++ P L P+ L + P PP +LP L P
Sbjct: 752 GAKELGAFLQKSPPPPPPTAQSTQPTPHGLLLEAGGPDLPLVLPPPPPQLLPSVLSHAPS 811
Query: 1283 PPPRPPRPPSPPPEPETTDASHPSVPPEPLAEDHPPHTPGLCGSLAKSQSTETVPATPGG 1342
P P + EP T D + PP P PP P + +S E +P
Sbjct: 812 PSPSASKVGVHLLEPATRDGAPQPPPPPP---PPPPPMPLQLEAHLRSHGLEPAAPSPRL 868
Query: 1343 EPPLSGGSSGLSLSSPQVPGSPFSYPAPSPSLSSGGLPRTPGRDFSFTPTFSEPSGPLLL 1402
P S G + ++ G+ P P+P + G P + G+D P+G
Sbjct: 869 RPEESLDPPG---AMQELLGALEPLP-PAPGDTGVGPPNSEGKD---------PAGAYR- 914
Query: 1403 PVCPLPTGRRDERSGPLASPVLLETGLPLPLPLPLPLPLALPAVLRAQARAPTPLPPLLP 1462
P P G + R PL S ++ L P + A P
Sbjct: 915 --SPSPQGTKAPRFVPLTSICFPDSLLQDEERSFFPTMEEMFGGGAADDYGKAGPPEDEG 972
Query: 1463 APLASCPPPMKRKPGRPRRSPPSMLSLDGPLVRPPAGAALGRE---LLLLPGQPQTPVFP 1519
P A PP PG P P GP P + G E L L P +P P P
Sbjct: 973 DPKAGAGPP----PGPPAYDPY------GPYC-PGRASGAGPETPGLGLDPNKP--PELP 1019
Query: 1520 STHDPRTVTLDFRNAGIPAPPPPLPPQPPPPPPPPPVEPTK 1560
ST + + L APPPP PPPPPPP P K
Sbjct: 1020 STVNAEPLGLIQSGPHQAAPPPP----PPPPPPPAPASEPK 1056
Score = 61.2 bits (147), Expect = 9e-09
Identities = 138/617 (22%), Positives = 186/617 (30%), Gaps = 169/617 (27%)
Query: 1154 AEESMASAGPEDFEQDGEEAA-LAPGAPAVDSLGM----------EEEVDIETEAVAPEE 1202
A + AGP + E D + A PG PA D G E + + P E
Sbjct: 958 AADDYGKAGPPEDEGDPKAGAGPPPGPPAYDPYGPYCPGRASGAGPETPGLGLDPNKPPE 1017
Query: 1203 RPSMLDEPPLPVGVEEPADSREPPEEPG------LSQEGAMLLSP--------------- 1241
PS ++ PL + P + PP P S+ L SP
Sbjct: 1018 LPSTVNAEPLGLIQSGPHQAAPPPPPPPPPPPAPASEPKGGLTSPIFCSTKPKKLLKTSS 1077
Query: 1242 -------EPP---------------AKEVEARPP----LSPERAPEHDLEVEPEPPM--M 1273
+PP A E +A P L+P R P+ P + +
Sbjct: 1078 FHLLRRRDPPFQTPKKLYAQEYEFEADEDKADVPADIRLNPRRLPDLVSSCRSRPALSPL 1137
Query: 1274 LPLPLQPPLPPPRPPRPPSPPPEPETTDASHPSVPPEPLAEDH--PPHTPGLCGSLAKSQ 1331
+ PP P P PR P D PP P P P G + S
Sbjct: 1138 GDIDFCPPNPGPDGPRRRGRKPTKAKRDG-----PPRPRGRPRIRPLEVPTTAGPASAST 1192
Query: 1332 STETVPATPG---GEPPLSGGSSGLSLSSPQVPGSPFSYPAPSPSLSSGGLPRTPGRDFS 1388
T+ G G + + G L + S P L + G D +
Sbjct: 1193 PTDGAKKPRGRGRGRGRKAEEAGGTRLEPLKPLKIKLSVPKAGEGLGTSSGDAISGTDHN 1252
Query: 1389 FTPTFSEPSGPLLLPVCPLPTGRRDERSGPLAS-----------PVLLETGLPLPLPLPL 1437
+ S + + + + + +SG +AS P L + GL PL P
Sbjct: 1253 SLDS-SLTREKIEAKIKEVEEKQPEMKSGFMASFLDFLKSGKRHPPLYQAGLTPPLSPPK 1311
Query: 1438 PLPLALPAVLRAQARAPTPLPPLLPA---PLAS--------------------CPPPMKR 1474
+P ++PA R P PP PA P S CP P KR
Sbjct: 1312 SVPPSVPA------RGLQPQPPATPAVPHPPPSGAFGLGGALEAAESEGLGLGCPSPCKR 1365
Query: 1475 KPGRPRRSPPSMLSL--------------------------DGPLVRP-----PAGAALG 1503
+R+ ++ S D PL P P G L
Sbjct: 1366 LDEELKRNLETLPSFSSDEEDSVAKNRDLQESISSAISALDDPPLAGPKDTSTPDGPPLA 1425
Query: 1504 RELLLLPGQPQTPVFPSTHDPRTVTLDFRNAGIPAPPPPLPPQPPPPPPPPPVEPTKLP- 1562
+PG P P PS + T P PPP P P PPPPPP LP
Sbjct: 1426 -PAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPS 1484
Query: 1563 ----FKELDNQWPSEAIPPGPRGRDEVTEEYMELAKSRGPWRRPPKKRHEDLVPPAGSPE 1618
+ P +PP P P PP PPA +P
Sbjct: 1485 PPPLVAPTPSSPPPPPLPPPP--------------PPAMPSPPPPP-------PPAAAPL 1523
Query: 1619 LSPPQPLFRPRSEFEEM 1635
+PP+ P E E+
Sbjct: 1524 AAPPEEPAAPSPEDPEL 1540
Score = 60.8 bits (146), Expect = 1e-08
Identities = 124/515 (24%), Positives = 174/515 (33%), Gaps = 112/515 (21%)
Query: 334 PAVTAVAGATAAFRGSSDLPFGAVGGTGGSSGPPFKAQPQD------------SATFAHT 381
P+ +GATA G + P A GG G G ++ Q +A A
Sbjct: 346 PSKAGPSGATAGASGRATGPEAAGGGGAGGGGGGYRPIIQSPGYKTGKGGYGAAAGGATR 405
Query: 382 PPPAQATPAPGFKSAFSP---YQTPVA----------HFPPPPEEPTATAAFGARDSGEF 428
PPP ++T P +S P Y T A + P P+ A+G G
Sbjct: 406 PPPPRSTATPKCQSLGGPAAAYATGKASGAGGAGGQAYSPGQPQGLLGPQAYGQGFGGGQ 465
Query: 429 RRAPAPPPLPPAEPLAKEKPGTPPGPPPPDTNSME------LGGRPTFGWSPEPCDSP-- 480
+ + P P P P GPPPP + + L G+ +G EP P
Sbjct: 466 AQDLSKAPSYSGGP-----PQPPSGPPPPGLATCQSYSPDQLQGQ-LYGVQGEPYPGPAA 519
Query: 481 ---GTPTLESS--------PA--------GPEKPHDSLDSRIEMLLKEQRTKLLFLREPD 521
G PT S PA GP ++ +++ ++ R P
Sbjct: 520 HSQGLPTASPSLSYSTGHSPALSGHGGGWGPSSLGGGGEASPSHIIRPLQSPPATGRPPG 579
Query: 522 SDTELQMEGSPISSSSSQLSPLAPFGTNSQP----GFRGPTPPSSRPSSTGLEDISPTPL 577
+ G +SS + LAP G S G++G S + G P
Sbjct: 580 VGSP-GAPGKYLSSVLASAPFLAPPGAGSYAAGAGGYKGKGDGSELLAGPG------GPP 632
Query: 578 PDSDEDEELDLGLGPRPPPEPGPPDPAGLLSQ--TAEVALDLVGDR-------TP----- 623
+ EDEE + + P P GL+ + A+ + L G TP
Sbjct: 633 AERTEDEEFLIQHLLQAPSPPRTSGADGLVGEDGAADASKGLGGSGGAGGPPGTPYELAK 692
Query: 624 -------------TSEKMDEGQQSSGEDMEISDDEMPSAPITSADCPKPM---VVTPGAA 667
TS +DEG ++ E E P + P+ + VV GA
Sbjct: 693 EDPQRYHLQSVIRTSASLDEGATAALELGLGRLKEKKKGPERGGETPEGLATSVVHYGAG 752
Query: 668 AVAAPSVLAPTLPLPPPPGFPPLPPPPPPPPPQPGFPMPPPLPPPPPPPPPAHPAVTVPP 727
A + L + P PPP P P G +P LPPPPP P+ + P
Sbjct: 753 AKELGAFLQKSPPPPPPTAQSTQPTPHGLLLEAGGPDLPLVLPPPPPQLLPSVLSHAPSP 812
Query: 728 PPLPAPPGV-------------PPPPILPPLPPFP 749
P + GV PPPP PP PP P
Sbjct: 813 SPSASKVGVHLLEPATRDGAPQPPPPPPPPPPPMP 847
Score = 60.8 bits (146), Expect = 1e-08
Identities = 117/462 (25%), Positives = 147/462 (31%), Gaps = 101/462 (21%)
Query: 333 SPAVTAVAGATAAFRGSSDLPFGAVGGTGGSSGPP------FKAQPQDS------ATFAH 380
SP T+ A G++D G +GG+GG+ GPP K PQ T A
Sbjct: 651 SPPRTSGADGLVGEDGAADASKG-LGGSGGAGGPPGTPYELAKEDPQRYHLQSVIRTSAS 709
Query: 381 TPPPAQATPAPGFKSAFSPYQTPVAHFPPPPEEPTATAAFGA--RDSGEF-RRAPAPPPL 437
A A G + P P T+ +GA ++ G F +++P PPP
Sbjct: 710 LDEGATAALELGLGRLKEKKKGPERGGETPEGLATSVVHYGAGAKELGAFLQKSPPPPP- 768
Query: 438 PPAEPLAKEKPGTPPG---------------PPPPDTNSMELGGRPTFGWSP-------- 474
P A+ TP G PPPP L P+ S
Sbjct: 769 ----PTAQSTQPTPHGLLLEAGGPDLPLVLPPPPPQLLPSVLSHAPSPSPSASKVGVHLL 824
Query: 475 EPCDSPGTPTLESSPAGPEKPHD-SLDSRIEMLLKEQRTKLLFLREPDSDTELQMEGSPI 533
EP G P P P P L++ + E LR +S L G+ +
Sbjct: 825 EPATRDGAPQPPPPPPPPPPPMPLQLEAHLRSHGLEPAAPSPRLRPEES---LDPPGA-M 880
Query: 534 SSSSSQLSPLAPFGTNSQPGFRGPTPPSSRPSSTGLEDISPTPLPDSDEDEELDLGLGPR 593
L PL P PG G PP+S SP+P PR
Sbjct: 881 QELLGALEPLPP-----APGDTGVGPPNSEGKDPAGAYRSPSPQGTK----------APR 925
Query: 594 PPPEPGPPDPAGLLSQTAEVALDLVGDRTPTSEKMDEGQQSSGEDMEISDDEMPSAPITS 653
P P LL PT E+M G + DD + P
Sbjct: 926 FVPLTSICFPDSLLQDEERSFF-------PTMEEMFGGGAA--------DDYGKAGPPED 970
Query: 654 ADCPKPMVVTPGAAAVAAPSVLAPTLPLPPPPGFPPLPPPPP-----PPPPQPGFPMPPP 708
PK GA P P PP + P P P P PG + P
Sbjct: 971 EGDPKA-----GAG------------PPPGPPAYDPYGPYCPGRASGAGPETPGLGLDPN 1013
Query: 709 LPPPPPPPPPAHPAVTVPPPPLPAPPGVPPPPILPPLPPFPP 750
PP P A P + P A P PPPP PP P P
Sbjct: 1014 KPPELPSTVNAEPLGLIQSGPHQAAPPPPPPPPPPPAPASEP 1055
Score = 53.1 bits (126), Expect = 3e-06
Identities = 44/147 (29%), Positives = 53/147 (36%), Gaps = 26/147 (17%)
Query: 366 PPFKAQPQDSATFAHTPPPAQATPAPGFKSAFSPYQTPVAHFPPPPEEPTATAAFGARDS 425
PP P ++ PP + P P A +P P PPPP P
Sbjct: 1434 PPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQP----PPPPPPPQPALPSPPPLV 1489
Query: 426 GEFRRAPAPPPLPPAEPLAKEKPGTPPGPPPPDTNSMELGGRPTFGWSPEPCDSPGTPTL 485
+P PPPLPP P P P PPPP + L P + P P
Sbjct: 1490 APTPSSPPPPPLPPPPP-----PAMPSPPPPPPPAAAPLAAPP---------EEPAAP-- 1533
Query: 486 ESSPAGPEKPHDSLDSRIEMLLKEQRT 512
SP PE P D+R L K+Q T
Sbjct: 1534 --SPEDPELP----DTRPLHLAKKQET 1554
Score = 51.2 bits (121), Expect = 1e-05
Identities = 110/451 (24%), Positives = 144/451 (31%), Gaps = 84/451 (18%)
Query: 356 AVGGTGGSSGPPFKAQPQDSATFAHTPPPAQATPAPGFKSAFSP------YQTPVAHFPP 409
A G TG GPP ++ +D A +P P Q T AP F S Q F P
Sbjct: 893 APGDTG--VGPP-NSEGKDPAGAYRSPSP-QGTKAPRFVPLTSICFPDSLLQDEERSFFP 948
Query: 410 PPEEPTATAA---FGA----RDSGEFRRAPAPPPLPPA-EPLAKEKPGTPPG-------- 453
EE A +G D G+ + PPP PPA +P PG G
Sbjct: 949 TMEEMFGGGAADDYGKAGPPEDEGDPKAGAGPPPGPPAYDPYGPYCPGRASGAGPETPGL 1008
Query: 454 ------PP--PPDTNSMELG---GRPTFGWSPEPCDSPGTPTLESSPAGPEKPHDSLDSR 502
PP P N+ LG P P P P P S P G ++
Sbjct: 1009 GLDPNKPPELPSTVNAEPLGLIQSGPHQAAPPPPPPPPPPPAPASEPKGGLTSPIFCSTK 1068
Query: 503 IEMLLKEQRTKLLFLREPDSDTELQMEGSPISSSSSQLSPLAPFGTNSQPGFRGPTPPS- 561
+ LLK LL R+P T ++ + + P P R P S
Sbjct: 1069 PKKLLKTSSFHLLRRRDPPFQTPKKLYAQEYEFEADEDKADVPADIRLNPR-RLPDLVSS 1127
Query: 562 --SRPSSTGLEDISPTPLPDSDEDEELDLGLGPRPPPEPGPPDPAG----------LLSQ 609
SRP+ + L DI P P+ D G P GPP P G +
Sbjct: 1128 CRSRPALSPLGDIDFCP-PNPGPDGPRRRGRKPTKAKRDGPPRPRGRPRIRPLEVPTTAG 1186
Query: 610 TAEVALDLVGDRTPTSEKMDEGQQ------------------------------SSGEDM 639
A + G + P G++ SSG+ +
Sbjct: 1187 PASASTPTDGAKKPRGRGRGRGRKAEEAGGTRLEPLKPLKIKLSVPKAGEGLGTSSGDAI 1246
Query: 640 EISDDEMPSAPITSADCPKPMVVTPGAAAVAAPSVLAPTLP-LPPPPGFPPLPPPPPPPP 698
+D + +T + +A L L PPL PP
Sbjct: 1247 SGTDHNSLDSSLTREKIEAKIKEVEEKQPEMKSGFMASFLDFLKSGKRHPPLYQAGLTPP 1306
Query: 699 PQPGFPMPPPLPPPP-PPPPPAHPAVTVPPP 728
P +PP +P P PPA PAV PPP
Sbjct: 1307 LSPPKSVPPSVPARGLQPQPPATPAVPHPPP 1337
Score = 47.8 bits (112), Expect = 1e-04
Identities = 107/441 (24%), Positives = 136/441 (30%), Gaps = 100/441 (22%)
Query: 1210 PPLPVGVEEPADSREPPEEPGLSQEGAMLLSPEPPAKEVEARPPLSPERAPEHDLEVEPE 1269
PP P + S P P S+ G LL EP ++ +PP P P
Sbjct: 795 PPPPPQLLPSVLSHAPSPSPSASKVGVHLL--EPATRDGAPQPPPPPP---------PPP 843
Query: 1270 PPMMLPLP-------LQPPLPPPR--------------------PPRPPSP------PPE 1296
PPM L L L+P P PR P PP+P PP
Sbjct: 844 PPMPLQLEAHLRSHGLEPAAPSPRLRPEESLDPPGAMQELLGALEPLPPAPGDTGVGPPN 903
Query: 1297 PETTDASHPSVPPEPLAEDHPPHTP--GLC--GSLAKSQSTETVPATP---GGEPPLSGG 1349
E D + P P P P +C SL + + P GG G
Sbjct: 904 SEGKDPAGAYRSPSPQGTKAPRFVPLTSICFPDSLLQDEERSFFPTMEEMFGGGAADDYG 963
Query: 1350 SSGLSLSSPQVPGSPFSYPAPSPSLSSGGLPRTPGRDFSFTPTFSEPSGPLLLPVCPLPT 1409
+G P+ G P + P P P +P G P CP
Sbjct: 964 KAG----PPEDEGDPKAGAGPPPG-----------------PPAYDPYG----PYCP--- 995
Query: 1410 GRRDERSGPLASPVLLETGLPLPLPLPLPL-PLALPAVLRAQARAPTPLPPLLPAPLASC 1468
R +GP + L+ P LP + PL L QA P P PP P AS
Sbjct: 996 -GRASGAGPETPGLGLDPNKPPELPSTVNAEPLGLIQSGPHQAAPPPPPPPPPPPAPASE 1054
Query: 1469 PPPMKRKPGRPRRSPPSMLSL---------DGPLVRPPAGAALGRELLLLPGQPQTPVFP 1519
P P P +L D P P A E + P
Sbjct: 1055 PKGGLTSPIFCSTKPKKLLKTSSFHLLRRRDPPFQTPKKLYAQEYEFEADEDKADVPADI 1114
Query: 1520 STHDPRTVTLDFRNAGIPAPPP--PLPPQPPPPPPPPPVEPTKLPFKELDNQWPSEAIPP 1577
+ R L PA P + PP P P P + P K + PP
Sbjct: 1115 RLNPRRLPDLVSSCRSRPALSPLGDIDFCPPNPGPDGPRRRGRKPTKAKRDG------PP 1168
Query: 1578 GPRGRDEVTEEYMELAKSRGP 1598
PRGR + +E+ + GP
Sbjct: 1169 RPRGRPRIRP--LEVPTTAGP 1187
Score = 47.4 bits (111), Expect = 1e-04
Identities = 64/240 (26%), Positives = 84/240 (35%), Gaps = 53/240 (22%)
Query: 1412 RDERSGPLASPVLLETGLP---LPLPLPLPLPLALPAVLRAQARAPTPLPPLL---PAPL 1465
R + GP AS +L + P + P P L + L + P+ PA
Sbjct: 98 RGPQPGPSASSLLSQFRSPSWQTAMHTPGPTELFISGALPGSSTFPSSSALSAYQHPASF 157
Query: 1466 ASCPPPMKRKPGRPRRSPPSMLSLDGPLVRPPAGAALGRELLLLPGQPQTPVFPSTHDPR 1525
S P P+ PS LSL P PPA L +L Q P PS+
Sbjct: 158 GSRPFPV-----------PSSLSLQDPPFSPPANGLLSPHDVLHLKPSQAPTVPSS---- 202
Query: 1526 TVTLDFRN---------AGI-PAPPPPLPPQPPPPPPPPPVEPTKLPF------------ 1563
L F AG+ PA PP P PP PPPPP PT+
Sbjct: 203 ---LGFERLAGGGVLGPAGLGPAQTPPYRPGPPDPPPPPRHLPTQFNLLASSSAAAAAAE 259
Query: 1564 ---KELDNQWPSEAIPPGPR----GRDEVTEEYMELAKSRGPWRRPPKKRHEDLVPPAGS 1616
+L N + PP P +D V + Y A ++ P PP + + GS
Sbjct: 260 QSSPQLYNFSGAAPGPPPPERALPRQDTVIKHYQRPASAQPPPPPPPAHALQHYLSCGGS 319
Score = 44.7 bits (104), Expect = 9e-04
Identities = 31/97 (31%), Positives = 34/97 (35%)
Query: 399 PYQTPVAHFPPPPEEPTATAAFGARDSGEFRRAPAPPPLPPAEPLAKEKPGTPPGPPPPD 458
P P A P PP P +A PPP PP P + +P PP PP P
Sbjct: 1422 PPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPA 1481
Query: 459 TNSMELGGRPTFGWSPEPCDSPGTPTLESSPAGPEKP 495
S PT P P P P SP P P
Sbjct: 1482 LPSPPPLVAPTPSSPPPPPLPPPPPPAMPSPPPPPPP 1518
Score = 44.3 bits (103), Expect = 0.001
Identities = 114/463 (24%), Positives = 143/463 (30%), Gaps = 136/463 (29%)
Query: 1287 PPRPPSPPPEPETTDASHPSVPPEPL--------AEDHP---PHTPGL-CGSLAKSQSTE 1334
PP+PPS PP P A+ S P+ L E +P H+ GL S + S ST
Sbjct: 479 PPQPPSGPPPPGL--ATCQSYSPDQLQGQLYGVQGEPYPGPAAHSQGLPTASPSLSYSTG 536
Query: 1335 TVPATPG-------------GE------------PPLSGGSSGLSLSSPQVPG------- 1362
PA G GE PP +G G+ SP PG
Sbjct: 537 HSPALSGHGGGWGPSSLGGGGEASPSHIIRPLQSPPATGRPPGVG--SPGAPGKYLSSVL 594
Query: 1363 --SPFSYPAPSPSLSSG------------------GLP--RTPGRDFSFTPTFSEPSGPL 1400
+PF P + S ++G G P RT +F PS P
Sbjct: 595 ASAPFLAPPGAGSYAAGAGGYKGKGDGSELLAGPGGPPAERTEDEEFLIQHLLQAPSPPR 654
Query: 1401 LLPVCPL--PTGRRDER-----SGPLASPVLLETGLPLPLPLPLPLPLALPAVLRAQARA 1453
L G D SG P G P L P L +V+R A
Sbjct: 655 TSGADGLVGEDGAADASKGLGGSGGAGGP----PGTPYELAKEDPQRYHLQSVIRTSASL 710
Query: 1454 PTPLPPLLPAPLASCPPPMKRKPGRPRRSPPSMLSLDGPLVRPPAGAA-LGRELLLLPGQ 1512
L L +K K P R + L +V AGA LG L P
Sbjct: 711 DEGATAALELGLGR----LKEKKKGPERGGETPEGLATSVVHYGAGAKELGAFLQKSPPP 766
Query: 1513 PQTPVFPSTHDPRTVTLDFRNAGIPAPPPPLPPQ-------------------------- 1546
P + P + L+ +P PP PPQ
Sbjct: 767 PPPTAQSTQPTPHGLLLEAGGPDLPLVLPPPPPQLLPSVLSHAPSPSPSASKVGVHLLEP 826
Query: 1547 ---------PPPPPPPPPVEPTKL----------PFKELDNQWPSEAIPPGPRGRDEVTE 1587
PPPPPPPPP P +L P P E++ P P E+
Sbjct: 827 ATRDGAPQPPPPPPPPPPPMPLQLEAHLRSHGLEPAAPSPRLRPEESLDP-PGAMQELLG 885
Query: 1588 EYMELAKSRGPWR-RPPKKRHEDLVPPAGSPELSPPQPLFRPR 1629
L + G PP +D PAG+ PQ PR
Sbjct: 886 ALEPLPPAPGDTGVGPPNSEGKD---PAGAYRSPSPQGTKAPR 925
Score = 42.0 bits (97), Expect = 0.006
Identities = 24/67 (35%), Positives = 32/67 (47%), Gaps = 8/67 (11%)
Query: 1287 PPRPPSPPPEPETTDASHPSVPPE-----PLAEDHPPHTPGLCGSLAKSQSTETVPATPG 1341
PP+ P+PPP+PET + + PPE + E P P L + K + E V
Sbjct: 1693 PPKAPAPPPKPETPEKTTSEKPPEQTPETAMPEPPAPEKPSLLRPVEKEKEKEKVTR--- 1749
Query: 1342 GEPPLSG 1348
GE PL G
Sbjct: 1750 GERPLRG 1756
Score = 41.2 bits (95), Expect = 0.010
Identities = 122/505 (24%), Positives = 156/505 (30%), Gaps = 92/505 (18%)
Query: 1159 ASAGPEDFEQDGEEAALAPGAPAVDSLGMEEEVDIETEAVAPEERPSMLDEPPLPVGVEE 1218
A AG + DG E PG P + +EE I+ AP P VG +
Sbjct: 610 AGAGGYKGKGDGSELLAGPGGPPAERT-EDEEFLIQHLLQAPS--PPRTSGADGLVGEDG 666
Query: 1219 PADSREPPEEPGLSQEGAMLLSPEPP---AKEVEARPPLSPERAPEHDLEVEPEPPMMLP 1275
AD+ + GL G P P AKE R L + ++ L
Sbjct: 667 AADASK-----GLGGSGGAGGPPGTPYELAKEDPQRYHL--QSVIRTSASLDEGATAALE 719
Query: 1276 LPLQPPLPPPRPPRPPSPPPEPETTDASHPSVPPEPLA---EDHPPHTPGLCGSLAKSQS 1332
L L + P PE T H + L + PP P +QS
Sbjct: 720 LGLGRLKEKKKGPERGGETPEGLATSVVHYGAGAKELGAFLQKSPPPPP------PTAQS 773
Query: 1333 TETVPATPGGEPPLSGGSSGLSLSSPQVPGSPFSYPAPSPSLSSGGLPRTPGRDFSFTPT 1392
T+ TP G +GG P P P P P L L P S +P+
Sbjct: 774 TQ---PTPHGLLLEAGG-----------PDLPLVLPPPPPQLLPSVLSHAP----SPSPS 815
Query: 1393 FSEPSGPLLLPVCPLPTGRRDERSGPLASPVLLETGLPLPLPLPLPLPLALPAVLRAQAR 1452
S+ LL P R G P P P P P P+PL L A LR+
Sbjct: 816 ASKVGVHLLEPA---------TRDGAPQPP-------PPPPPPPPPMPLQLEAHLRSHGL 859
Query: 1453 APTPLPPLLPAPLASCPP-----------PMKRKPGRPRRSPPSMLSLD--GPLVRP-PA 1498
P P L + PP P+ PG PP+ D G P P
Sbjct: 860 EPAAPSPRLRPEESLDPPGAMQELLGALEPLPPAPGDTGVGPPNSEGKDPAGAYRSPSPQ 919
Query: 1499 GAALGRELLL--------LPGQPQTPVFPSTHD--PRTVTLDFRNAGIPAPPPPLPPQPP 1548
G R + L L + FP+ + D+ AG P
Sbjct: 920 GTKAPRFVPLTSICFPDSLLQDEERSFFPTMEEMFGGGAADDYGKAGPPEDEGDPKAGAG 979
Query: 1549 PPPPPPPVEPTKLPFKELDNQWPSEAIPPGPR----GRDEVTEEYMELAKSRGPWRRPPK 1604
PPP PP +P P A GP G D + + P
Sbjct: 980 PPPGPPAYDP-------YGPYCPGRASGAGPETPGLGLDPNKPPELPSTVNAEPLGLIQS 1032
Query: 1605 KRHEDLVPPAGSPELSPPQPLFRPR 1629
H+ PP P PP P P+
Sbjct: 1033 GPHQ-AAPPPPPPPPPPPAPASEPK 1056
Score = 39.3 bits (90), Expect = 0.037
Identities = 29/97 (29%), Positives = 31/97 (31%), Gaps = 46/97 (47%)
Query: 669 VAAPSVLAPTLPLPPPPGFPPLPPPPP--------------------------------- 695
V P+ L P P PG PP PPPPP
Sbjct: 213 VLGPAGLGPAQTPPYRPG-PPDPPPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNFSGA 271
Query: 696 ---PPPPQPGFPMP---------PPLPPPPPPPPPAH 720
PPPP+ P P PPPPPPPAH
Sbjct: 272 APGPPPPERALPRQDTVIKHYQRPASAQPPPPPPPAH 308
Score = 39.3 bits (90), Expect = 0.037
Identities = 29/97 (29%), Positives = 36/97 (37%), Gaps = 15/97 (15%)
Query: 409 PPPEEPTATAAFGARDSGEFRRAPAPPPLP----------PAEPLAKEKPGTPPGPPPPD 458
PP P T+ P PPPLP P PL +EKP PP PPP
Sbjct: 1408 PPLAGPKDTSTPDGPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKP--PPTPPPAP 1465
Query: 459 TNSMELGGRPTFGWSPEPCDSPGTPTLESSPAGPEKP 495
T + P P+P P + +P+ P P
Sbjct: 1466 TPQPQPPPPPP---PPQPALPSPPPLVAPTPSSPPPP 1499
Score = 38.9 bits (89), Expect = 0.049
Identities = 55/214 (25%), Positives = 69/214 (32%), Gaps = 27/214 (12%)
Query: 688 PPLPPPPPPPPPQP----GFPMPPPLPPPPPPPPPAHPAVTVPPPPLPAPPGVPPPPILP 743
PP+P P G PPP P PPP P T PP P P P
Sbjct: 1670 PPVPVRRSGQAKNPVSAGGSSAPPPKAPAPPPKPETPEKTTSEKPPEQTPETAMPE---P 1726
Query: 744 PLPPFPPGLFPV-MQVDMSHVLGGQ--WGGMPMSFQMQTQVLSRLMTGQGACPYPPFMAA 800
P P P L PV + + V G+ G + QT+ L TGQ A P
Sbjct: 1727 PAPEKPSLLRPVEKEKEKEKVTRGERPLRGERATSGRQTRPERSLATGQPATSRLPKARP 1786
Query: 801 AAAAASAGLQFVNLPPYRGPFSLSNSGPGRGQHWPPLPKFDPSVPPPGYMPRQEDPHKAT 860
A PP + L +G PPG E A
Sbjct: 1787 TKVKAEP-------PPKKRKKWLKEAGGNA----------TAGGGPPGSSSDSESSPGAP 1829
Query: 861 VDGVLLVVLKELKAIMKRDLNRKMVEVVAFRAFD 894
+ V + LK R++ R VE++ A D
Sbjct: 1830 SEDERAVPGRLLKTRAMREMYRSYVEMLVSTALD 1863
Score = 38.1 bits (87), Expect = 0.084
Identities = 87/386 (22%), Positives = 117/386 (30%), Gaps = 70/386 (18%)
Query: 1195 TEAVAPEERPSMLDEPPLPVGVEEPADSREPPEEPGLSQEGAMLLSPEPPAKEVEARPPL 1254
+ A++ + P+ P PV S ++P S LLSP + +P
Sbjct: 145 SSALSAYQHPASFGSRPFPV------PSSLSLQDPPFSPPANGLLSPHDV---LHLKPSQ 195
Query: 1255 SPERAPEHDLEVEPEPPMMLPLPLQPPLPPPRPPRPPSPPPEPETTDASHPSVPPEPLAE 1314
+P E ++ P L P PP P PP PPP PP L
Sbjct: 196 APTVPSSLGFERLAGGGVLGPAGLGPAQTPPYRPGPPDPPP------------PPRHLPT 243
Query: 1315 DHPPHTPGLCGSLAKSQSTETV----PATPGGEPPLSG-GSSGLSLSSPQVPGSPFSYPA 1369
+ A QS+ + A PG PP + Q P S P
Sbjct: 244 QFNLLASSSAAAAAAEQSSPQLYNFSGAAPGPPPPERALPRQDTVIKHYQRPASAQPPPP 303
Query: 1370 PSPS------LSSGGLPRTPGR--DFSFTPT-FSEPSGPLLLPVCPLPTGRRDERSGPLA 1420
P P+ LS GG + G + + +P EPS P P+G SG
Sbjct: 304 PPPAHALQHYLSCGGSYPSMGHRANLACSPLGGGEPSPGAGEPSKAGPSGATAGASGRAT 363
Query: 1421 SPVLLETGLPLPLPLPLPLPLALPAVLRAQARAPTPLPPLLPAP--------LASCPPPM 1472
P G P++ +P +
Sbjct: 364 GPEAAGGG--------------------GAGGGGGGYRPIIQSPGYKTGKGGYGAAAGGA 403
Query: 1473 KRKPGRPRRSPPSMLSLDGPLVRPPAGAALGR----ELLLLPGQPQTPVFPSTHDP---R 1525
R P + P SL GP G A G PGQPQ + P +
Sbjct: 404 TRPPPPRSTATPKCQSLGGPAAAYATGKASGAGGAGGQAYSPGQPQGLLGPQAYGQGFGG 463
Query: 1526 TVTLDFRNAGIPAPPPPLPPQPPPPP 1551
D A + PP PP PPPP
Sbjct: 464 GQAQDLSKAPSYSGGPPQPPSGPPPP 489
Score = 36.2 bits (82), Expect = 0.32
Identities = 58/228 (25%), Positives = 80/228 (35%), Gaps = 45/228 (19%)
Query: 283 FSQDSSYSSRQ-PTPSYLFSQDPAVTFKARRHESKFTDAYNRRHEHHYVHNSPAVTAVAG 341
+ +S+ SR P PS L QDP + A S H +H P+
Sbjct: 151 YQHPASFGSRPFPVPSSLSLQDPPFSPPANGLLSP----------HDVLHLKPSQAPTVP 200
Query: 342 ATAAFRGSSDLPFGAVGGTGGSSGPPFKAQPQDSATFAHTPPPAQATP-------APGFK 394
++ F + G G + PP++ P D PPP + P +
Sbjct: 201 SSLGFERLAGGGVLGPAGLGPAQTPPYRPGPPDP------PPPPRHLPTQFNLLASSSAA 254
Query: 395 SAFSPYQTP-------VAHFPPPPEEPTATAAFGARDS---GEFRRAPAPPPLPPAEPLA 444
+A + +P A PPPPE A +D+ R A A PP PP A
Sbjct: 255 AAAAEQSSPQLYNFSGAAPGPPPPER-----ALPRQDTVIKHYQRPASAQPPPPPPPAHA 309
Query: 445 KEKPGTPPGPPPPDTNSMELGGRPTFGWSPEPCDSPGTPTLESSPAGP 492
+ + G P + L P G P SPG E S AGP
Sbjct: 310 LQHYLSCGGSYPSMGHRANLACSPLGGGEP----SPGAG--EPSKAGP 351
Score = 35.4 bits (80), Expect = 0.54
Identities = 44/177 (24%), Positives = 60/177 (33%), Gaps = 39/177 (22%)
Query: 1210 PPLPVG--------VEEPADSREPPEEPGLSQEGAMLLSPEPPAKEVEARPPLSPERAPE 1261
PP+PV V S PP+ P + PE P K +PP E+ PE
Sbjct: 1670 PPVPVRRSGQAKNPVSAGGSSAPPPKAPAPPPK------PETPEKTTSEKPP---EQTPE 1720
Query: 1262 HDLEVEPEPPMMLPLPLQPPLPPPRPPRPPSPPPEP---ETTDASHPSVPPEPLAEDHPP 1318
+ PEPP L P+ + + P E + + P LA P
Sbjct: 1721 TAM---PEPPAPEKPSLLRPVEKEKEKEKVTRGERPLRGERATSGRQTRPERSLATGQPA 1777
Query: 1319 HTPGLCGSLAKSQSTETVPATP-----------GGEPPLSGGSSGLSLSSPQVPGSP 1364
+ L K++ T+ P GG GG G S S PG+P
Sbjct: 1778 TS-----RLPKARPTKVKAEPPPKKRKKWLKEAGGNATAGGGPPGSSSDSESSPGAP 1829
Score = 34.7 bits (78), Expect = 0.92
Identities = 70/266 (26%), Positives = 86/266 (32%), Gaps = 79/266 (29%)
Query: 1329 KSQSTETVPATPGG-EPPLSGGSSGLS-------LSSPQVPGSPFSYPAPSPSLSSGGLP 1380
+S S +T TPG E +SG G S LS+ Q P S S P P PS S
Sbjct: 114 RSPSWQTAMHTPGPTELFISGALPGSSTFPSSSALSAYQHPASFGSRPFPVPSSLS---- 169
Query: 1381 RTPGRDFSFTPTFSEPSGPLLLPVCPLPTGRRDERSGPLASPVLLETGLPLPLPLPLPLP 1440
P FS P+ LL P L + ++ + S + E
Sbjct: 170 -------LQDPPFSPPANGLLSPHDVLHL--KPSQAPTVPSSLGFER------------- 207
Query: 1441 LALPAVLRAQARAPTPLPPLLPAPLASCPPPMKRKPGRPRRSPPSMLSLDGPLVRPPAGA 1500
LA VL P PP P P PPP R P+ +L L A A
Sbjct: 208 LAGGGVLGPAGLGPAQTPPYRPGPPDPPPPP---------RHLPTQFNL---LASSSAAA 255
Query: 1501 ALGRELLLLPGQPQTPVFPSTHDPRTVTLDFRNAGIPAPPPP---LP-----------PQ 1546
A + PQ F + P PPPP LP P
Sbjct: 256 AAAEQ-----SSPQLYNF--------------SGAAPGPPPPERALPRQDTVIKHYQRPA 296
Query: 1547 PPPPPPPPPVEPTKLPFKELDNQWPS 1572
PPPPPP + +PS
Sbjct: 297 SAQPPPPPPPAHALQHYLSCGGSYPS 322
Score = 34.7 bits (78), Expect = 0.92
Identities = 19/46 (41%), Positives = 22/46 (47%), Gaps = 2/46 (4%)
Query: 709 LPPPPPPPPPAHPAVTVPPPPLPAPPGVPPPPILPPLPPFPPGLFP 754
L PPPPPP + P L G P P++ LPP PP L P
Sbjct: 760 LQKSPPPPPPTAQSTQPTPHGLLLEAGGPDLPLV--LPPPPPQLLP 803
Score = 34.7 bits (78), Expect = 0.92
Identities = 20/59 (33%), Positives = 23/59 (38%), Gaps = 5/59 (8%)
Query: 682 PPPPGFPPLPPPP-PPPPPQPGFPMPPPLPPPPPPPPPAHPAVTVPPPPLPAPPGVPPP 739
P G PPP P PPP+P P PP P +P PP P P + P
Sbjct: 1683 PVSAGGSSAPPPKAPAPPPKP----ETPEKTTSEKPPEQTPETAMPEPPAPEKPSLLRP 1737
Score = 33.9 bits (76), Expect = 1.6
Identities = 30/128 (23%), Positives = 48/128 (37%), Gaps = 4/128 (3%)
Query: 1110 TSSSESSESSEFESSSESSPSSSEDEEEVVAREEEEEEEEEEMV-AEESMASAGPEDFEQ 1168
T +SE ++ + P E+ + R E+E+E+E++ E + Q
Sbjct: 1705 TPEKTTSEKPPEQTPETAMPEPPAPEKPSLLRPVEKEKEKEKVTRGERPLRGERATSGRQ 1764
Query: 1169 DGEEAALAPGAPAVDSLGMEEEVDIETEAVAPEERPSMLDEP--PLPVGVEEPADSREPP 1226
E +LA G PA L ++ E P++R L E G P S +
Sbjct: 1765 TRPERSLATGQPATSRLPKARPTKVKAEP-PPKKRKKWLKEAGGNATAGGGPPGSSSDSE 1823
Query: 1227 EEPGLSQE 1234
PG E
Sbjct: 1824 SSPGAPSE 1831
Score = 33.1 bits (74), Expect = 2.7
Identities = 41/142 (28%), Positives = 52/142 (36%), Gaps = 19/142 (13%)
Query: 1471 PMKRKPGRPRRSPPSM--LSLDGPLVRPPAGAALGRELLLLPGQPQTPVFPSTHDPRTVT 1528
P R P RRS + +S G PP A P +P+TP ++ P T
Sbjct: 1666 PWHRPPVPVRRSGQAKNPVSAGGSSAPPPKAPAP-------PPKPETPEKTTSEKPPEQT 1718
Query: 1529 LDFRNAGIPAPPPPLPPQPPPPPPPPPVEPTKLPFKELDNQWP--SEAIPPGPRGRDEVT 1586
P P PP P P PVE K K + P E G + R E +
Sbjct: 1719 --------PETAMPEPPAPEKPSLLRPVEKEKEKEKVTRGERPLRGERATSGRQTRPERS 1770
Query: 1587 EEYMELAKSRGPWRRPPKKRHE 1608
+ A SR P RP K + E
Sbjct: 1771 LATGQPATSRLPKARPTKVKAE 1792
>gi|23510384 enhancer of zeste 2 isoform b [Homo sapiens]
Length = 707
Score = 102 bits (254), Expect = 4e-21
Identities = 50/124 (40%), Positives = 75/124 (60%), Gaps = 2/124 (1%)
Query: 1783 KKKLKFCKSHIHDWGLFAMEPIAADEMVIEYVGQNIRQVIADMREKRYEDEGIGSSYMFR 1842
KK L S + WG+F +P+ +E + EY G+ I Q AD R K Y+ S++F
Sbjct: 572 KKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDK--YMCSFLFN 629
Query: 1843 VDHDTIIDATKCGNFARFINHSCNPNCYAKVITVESQKKIVIYSKQHINVNEEITYDYKF 1902
+++D ++DAT+ GN RF NHS NPNCYAKV+ V +I I++K+ I EE+ +DY++
Sbjct: 630 LNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFFDYRY 689
Query: 1903 PIED 1906
D
Sbjct: 690 SQAD 693
>gi|21361095 enhancer of zeste 2 isoform a [Homo sapiens]
Length = 751
Score = 102 bits (254), Expect = 4e-21
Identities = 50/124 (40%), Positives = 75/124 (60%), Gaps = 2/124 (1%)
Query: 1783 KKKLKFCKSHIHDWGLFAMEPIAADEMVIEYVGQNIRQVIADMREKRYEDEGIGSSYMFR 1842
KK L S + WG+F +P+ +E + EY G+ I Q AD R K Y+ S++F
Sbjct: 616 KKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDK--YMCSFLFN 673
Query: 1843 VDHDTIIDATKCGNFARFINHSCNPNCYAKVITVESQKKIVIYSKQHINVNEEITYDYKF 1902
+++D ++DAT+ GN RF NHS NPNCYAKV+ V +I I++K+ I EE+ +DY++
Sbjct: 674 LNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFFDYRY 733
Query: 1903 PIED 1906
D
Sbjct: 734 SQAD 737
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
Length = 855
Score = 102 bits (253), Expect = 5e-21
Identities = 108/347 (31%), Positives = 134/347 (38%), Gaps = 55/347 (15%)
Query: 1238 LLSPEPPAKEVEARPPLSPERAPEHDLEVEPEPPMMLPLPLQPPLPPPRP-----PRPPS 1292
L +P P A PP P L + + PLPL PP P P P PP+
Sbjct: 304 LATPSPSAALQSQAPPTLPATPHSSSLTCQ----LATPLPLAPPSPSAPPSLQTLPSPPA 359
Query: 1293 PPPEPETTD-------ASH---PSVPPEPLAEDHPPHTPGLCGSLAKSQSTETVPATPGG 1342
PP TT A+H PS P PLA P P L +L Q+ P +P
Sbjct: 360 TPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPAL--ALPPLQA----PPSPPA 413
Query: 1343 EPPLSGGSSGLSLSSPQVPGS--------PFSYPAPSPSLSSGGLPRTPGRDFSFTPTFS 1394
PPLS L+ SPQ P + PFS P P + P +P S TP
Sbjct: 414 SPPLSP----LATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQ 469
Query: 1395 EPSGPLLLPVCPLPTGRRDERSGPLASPVLLETGLPLPLPLPLPLPLALPAVLRAQARAP 1454
P L P +P P ASP + + P P P PLA P + A+
Sbjct: 470 APPS-LAAPPLQVPPS-------PPASPPMSPSATPPP---QAPPPLAAPPLQLAKPPPQ 518
Query: 1455 TPLPPLLPAPLASCPPPMKRKPGRPRRSPPSMLSLDGPLVRPPAGA--ALGRELLLLPGQ 1512
P P L PL + P P PG+ SP + L + PL PP A L LL +P
Sbjct: 519 AP-PALATPPLQALPSPPASFPGQAPFSPSASLPMS-PLATPPPQAPPVLAAPLLQVP-- 574
Query: 1513 PQTPVFPSTHDPRTVTLDFRNAGIPAPPPPLPPQPPPPPPPPPVEPT 1559
P P P+ PR + + P L P PPPPP P+
Sbjct: 575 PSPPASPTLQAPRRPPTPGPDTSVSGPRLTLA-LAPGPPPPPSRSPS 620
Score = 99.8 bits (247), Expect = 2e-20
Identities = 122/468 (26%), Positives = 167/468 (35%), Gaps = 67/468 (14%)
Query: 1176 APGA-PAVDSLGMEEEVDIETEAVAPEERPSMLDEPPLPVGVEEPAD------------- 1221
AP A P + G + V +E E P+ P G++ PA
Sbjct: 193 APSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSP 252
Query: 1222 SREPPEEPGLSQEGAMLLSPEPPAKEVEARPPLSPERAPEHDLEVEPEPPMMLPLPLQPP 1281
+R P G + A P+P + P ++P P D P PL P
Sbjct: 253 ARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTP---PRKDAAPALGPLSSSPLATPSP 309
Query: 1282 LPPPRPPRPPSPPPEPETTDASHPSVPPEPLAEDHPPHTPGLCGSLAKSQSTETVPATPG 1341
+ PP+ P P ++ + P PLA P P L Q+ + PATP
Sbjct: 310 SAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSL-------QTLPSPPATPP 362
Query: 1342 GEPPLSGGSSGLSLSSPQVPGSPFSYPAPSPSLSSGGLPRTPGRDFSFTPTFSEPSGPLL 1401
+ S GS L + +P P S A P P+ P + P + PS P
Sbjct: 363 SQATTSLGSPTLQATHSFLPSPPLSPLATPP-------PQAPPA-LALPPLQAPPSPPAS 414
Query: 1402 LPVCPLPTGRRDERSGPLASPVLLETGLPLPLPLPLPLPLALPAV--LRAQARAPTPLPP 1459
P+ PL T + LA +L P P P P+ P + PA + A P+ PP
Sbjct: 415 PPLSPLATPS-PQAPNALAVHLLQAPFSPPPSP-PVQAPFSPPASPPVSPSATPPSQAPP 472
Query: 1460 LLPAPLASCPP------PMKRKPGRPRRSPPSMLSLDGPLVRPPAGAALGRELLLLPGQP 1513
L AP PP PM P ++PP + + L +PP A L P
Sbjct: 473 SLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALP 532
Query: 1514 QTPVFPSTHDPRTVTLDFRNAGIPAPPPPLPPQPPPP----PPPPPVEPTKLPFKELDNQ 1569
P P + + + + PPP PP P PP PP PT Q
Sbjct: 533 SPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTL--------Q 584
Query: 1570 WPSEAIPPGPRGRDEVTEEYMELAKSRGPWRRPPKKRHEDLVPPAGSP 1617
P PP P V+ + LA + GP PP PP+ SP
Sbjct: 585 APRR--PPTPGPDTSVSGPRLTLALAPGP---PP--------PPSRSP 619
Score = 90.1 bits (222), Expect = 2e-17
Identities = 125/501 (24%), Positives = 171/501 (34%), Gaps = 59/501 (11%)
Query: 358 GGTGGSSGPPFKAQPQDSATFAHTPPPAQAT----PAPGFKSAFSPYQTPVAHFPPPPEE 413
G T G+ P + + + T P PA + P G + + S P P
Sbjct: 166 GPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAAR 225
Query: 414 PTATAAFGA-RDSGEFRRAPAPPPLPPAE--PLAKEKPGTPPGPPPPDTNSMELGGRPTF 470
+A G R + + A P PA P A+ P P P P ++ RP
Sbjct: 226 RRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQ-ALRPPQ 284
Query: 471 GWSPEPCDSPGTPTLESSPAGPEKPHDSLDSRIEMLLKEQRTKLLFLREPDSDTELQMEG 530
P +P L SSP P +L S+ L P S +
Sbjct: 285 VTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPAT---------PHSSSLTCQLA 335
Query: 531 SPISSSSSQLSPLAPFGTNSQPGFRG-PTPPSSRPSSTGLEDISPTPLPDSDEDEELDLG 589
+P+ PLAP ++ P + P+PP++ PS SPT L
Sbjct: 336 TPL--------PLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLS 387
Query: 590 LGPRPPPEPGP----PDPAGLLSQTAEVALDLVGDRTPTSEKMDEGQQSSGEDMEISDDE 645
PPP+ P P S A L + +P + + + +
Sbjct: 388 PLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNA----------LAVHLLQ 437
Query: 646 MPSAPITSADCPKPMVVTPGAAAVAAPSVLAPTLPLPPPPGFPPLPPPPPPPPPQPGFPM 705
P +P S P +P A+ +PS P+ PP PPL PP PP P
Sbjct: 438 APFSPPPSPPVQAPF--SPPASPPVSPSATPPS-QAPPSLAAPPLQVPPSPPASPP--MS 492
Query: 706 PPPLPPPPPPPPPAHPAVTVPPPPLPAPPGVPPPPILPPLPPFPPGLFPVMQVDMSHVLG 765
P PPP PPP A P + + PP APP + PP+ P PP FP
Sbjct: 493 PSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPL--QALPSPPASFP----------- 539
Query: 766 GQWGGMPMSFQMQTQVLSRLMTGQGACPYPPFMAAAAAAASAGLQFVNLPPYRGPFSLSN 825
GQ P + + + + P + AS LQ PP GP S
Sbjct: 540 GQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGP-DTSV 598
Query: 826 SGPGRGQHWPPLPKFDPSVPP 846
SGP P P PS P
Sbjct: 599 SGPRLTLALAPGPPPPPSRSP 619
Score = 88.6 bits (218), Expect = 5e-17
Identities = 138/542 (25%), Positives = 187/542 (34%), Gaps = 80/542 (14%)
Query: 216 ETLQLSDALKRLKDGGLSAGCGSGSSSVTPNSGGTPFSQDTAYSSCRLDTPNSYGQGTPL 275
ET+ A + K LSAG +S TP + ++ + + + P P
Sbjct: 140 ETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPR 199
Query: 276 TPRLGT--PFSQDSSYSSRQPTPSYLFSQDPAVTFKARRHESKFTDAYNRRHEHHYVHNS 333
P G S S +S+ +P+P+ ARR S R ++
Sbjct: 200 PPTEGPRKSVSSASEHSTTEPSPA------------ARRRPSA-GGGLQRPASRSLSSSA 246
Query: 334 PAVTAVAGATAAFRGSSDLPFGAVGGTGGSSGPPFKAQPQDSATFAH---TPPPAQATPA 390
+++ A + + RG+ P P + +P+ TPP A PA
Sbjct: 247 TPLSSPARSGPSARGTPRAP-----------AHPSQPKPKGLQALRPPQVTPPRKDAAPA 295
Query: 391 PGFKSAFSPYQTPVAHFPPPPEEPTATAAFGARDSGEFRRA---PAPPPLPPAEPLAKEK 447
G S+ SP TP + P A S + A P PP P A P +
Sbjct: 296 LGPLSS-SPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTL 354
Query: 448 PGTPPGPPPPDTNSMELGGRPTF----GWSPEPCDSP-GTPTLESSPA-------GPEKP 495
P P PP T S+ G PT + P P SP TP ++ PA P P
Sbjct: 355 PSPPATPPSQATTSL---GSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSP 411
Query: 496 HDSLDSRIEMLLKEQRTKLLFLREPDSDTELQMEGSPISSSSSQLSPLAPFGTNSQPGFR 555
S Q L + LQ SP S Q APF + P
Sbjct: 412 PASPPLSPLATPSPQAPNALAVHL------LQAPFSPPPSPPVQ----APFSPPASPPVS 461
Query: 556 -GPTPPSSRPSSTGLEDISPTPLPDSDEDEELDLGLGPRPPPEPGPPDPAGLLSQTAEVA 614
TPPS P S + P P + + PPP+ PP A L
Sbjct: 462 PSATPPSQAPPSLAAPPLQVPPSPPASPP----MSPSATPPPQAPPPLAAPPLQLAKPPP 517
Query: 615 LDLVGDRTPTSEKMDEGQQSSGEDMEISDDEMPSAPITSADCPKPMVVTPGAAAVAAPSV 674
TP + + S + P +P SA P + TP A P +
Sbjct: 518 QAPPALATPPLQALPSPPASF-------PGQAPFSP--SASLPMSPLATPPPQA--PPVL 566
Query: 675 LAPTLPLPP-PPGFPPLPPPPPPPPPQPGFPMPPP-----LPPPPPPPPPAHPAVTVPPP 728
AP L +PP PP P L P PP P P + P L P PPPPP P+ T+ P
Sbjct: 567 AAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGP 626
Query: 729 PL 730
L
Sbjct: 627 DL 628
Score = 86.3 bits (212), Expect = 3e-16
Identities = 146/550 (26%), Positives = 188/550 (34%), Gaps = 89/550 (16%)
Query: 333 SPAVTAVAGATAAFRGSSDLPFGAVGGTGGSSGP---PFKAQPQDSATFAHTP---PPA- 385
+PA V GA A G L A GG GG++ P P + + T + P PPA
Sbjct: 40 TPAALRVLGAAGAV-GRKPLAERA-GGIGGATIPESAPRAGPTRSAGTSSRNPASRPPAS 97
Query: 386 -QATPAPGFKSAFSPYQTPVAHFPPPPEEPTATAAFGARDSGEF-----RRAPAPPPLPP 439
+ AP K+ SP P G R S E + AP
Sbjct: 98 GRGERAPPAKNT-SPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSAL 156
Query: 440 AEPLAKEKPGTPPGPPPPDTNSMELGGRPTFGWS-PEPCDSPGTPTLESSPAGPEKPHDS 498
+ ++ G PG P P G P P P PT E P S
Sbjct: 157 SAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPT--------EGPRKS 208
Query: 499 LDSRIEMLLKEQRTKLLFLREPDSDTELQMEGS-PISSSSSQLSPLAPFGTNSQPGFRGP 557
+ S E E R P + LQ S +SSS++ LS A G +++ R P
Sbjct: 209 VSSASEHSTTEPSPAAR--RRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAP 266
Query: 558 TPPSSRPSSTGLEDISPTPLPDSDEDEELDLGLGPRPPPEPGPPDPAGLLSQTAEVALDL 617
PS +P GL+ + P + +D LGP P P+ L A L
Sbjct: 267 AHPS-QPKPKGLQALRPPQVTPPRKDAAP--ALGPLSSSPLATPSPSAALQSQAPPTLPA 323
Query: 618 VGDRTPTSEKMDEGQQSSGEDMEISDDEMPSAPITSADCPKPMVVTPGAA--AVAAPSVL 675
TP S + + ++ PSAP + P P P A ++ +P++
Sbjct: 324 ----TPHSSSLT---CQLATPLPLAPPS-PSAPPSLQTLPSPPATPPSQATTSLGSPTLQ 375
Query: 676 APTLPLPPPPGFPPLPPPPPPPPPQPGFPMPPPLPPPPPPPPPAHPAVTVPPPPLPAPPG 735
A LP PP PL PPP PP P P PP PP PP P T P P P
Sbjct: 376 ATHSFLPSPP-LSPLATPPPQAPPALALP-PLQAPPSPPASPPLSPLAT-PSPQAPNALA 432
Query: 736 V-------PPPPILPPLPPFPPGLFPVMQVDMSHVLGGQWGGMPMSFQMQTQVLSRLMTG 788
V PPP P PF P P + +
Sbjct: 433 VHLLQAPFSPPPSPPVQAPFSPPASPPVSPSAT--------------------------- 465
Query: 789 QGACPYPPFMAAAAAAASAGLQFVNLPPYRGPFSLSNSGPGRGQHWPPL--PKFDPSVPP 846
PP A + AA LQ PP P S S + P + PPL P + PP
Sbjct: 466 ------PPSQAPPSLAAPP-LQVPPSPPASPPMSPSATPPPQAP--PPLAAPPLQLAKPP 516
Query: 847 PGYMPRQEDP 856
P P P
Sbjct: 517 PQAPPALATP 526
Score = 84.0 bits (206), Expect = 1e-15
Identities = 117/435 (26%), Positives = 153/435 (35%), Gaps = 110/435 (25%)
Query: 1278 LQPPLPPPRPPRPPSPPPEPETTDAS-HPSVPPEPLAEDHPPHTPGLCGSLAKSQSTETV 1336
L P P R PRPP+ P + AS H + P P A P GL ++S S+
Sbjct: 189 LPRPAPSAR-PRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSAT 247
Query: 1337 P-ATPGGEPPLSGGS------------SGL-SLSSPQV--------------PGSPFSYP 1368
P ++P P + G+ GL +L PQV SP + P
Sbjct: 248 PLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATP 307
Query: 1369 APSPSLSSGGLPRTPGRDFSFTPTFS----------EPSGPLLLPVCPLPTGR-RDERSG 1417
+PS +L S P P S + T PS P L P P + +
Sbjct: 308 SPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATT 367
Query: 1418 PLASPVLLETGLPLP----LPLPLPLPLALPAVLRAQARAPTPLPP-------------- 1459
L SP L T LP PL P P A PA+ +AP P PP
Sbjct: 368 SLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAP-PSPPASPPLSPLATPSPQ 426
Query: 1460 --------LLPAPLASCPPPMKRKPGRPRRSPPSMLSLDGPLVRPPAGAALGRELLLLPG 1511
LL AP + P P + P P SPP S P PP+ AA L + P
Sbjct: 427 APNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAA--PPLQVPPS 484
Query: 1512 QPQT-PVFPSTHDPRTVTLDFRNAGIPAPPPPL----------PPQPPPP---------P 1551
P + P+ PS P P PPPL PPQ PP P
Sbjct: 485 PPASPPMSPSATPP------------PQAPPPLAAPPLQLAKPPPQAPPALATPPLQALP 532
Query: 1552 PPPPVEPTKLPFKELDNQWPSEAIPPGPRGRDEVTEEYMELAKS--RGPWRRPPKKRHED 1609
PP P + PF + S P P+ + +++ S P + P++
Sbjct: 533 SPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRR---- 588
Query: 1610 LVPPAGSPELSPPQP 1624
PP P+ S P
Sbjct: 589 --PPTPGPDTSVSGP 601
Score = 58.9 bits (141), Expect = 5e-08
Identities = 112/422 (26%), Positives = 138/422 (32%), Gaps = 94/422 (22%)
Query: 1275 PLPLQPPLPPPRPPRPPSPPPEPETTDA-----SHPSVPPEPLAEDHPPHTPGLCGS--- 1326
P P L PRPP P PPP P T A + +V +PLAE G+ G+
Sbjct: 17 PAARAPGLLTPRPPGSPRPPP-PVTPAALRVLGAAGAVGRKPLAE----RAGGIGGATIP 71
Query: 1327 -----LAKSQSTETVPATPGGEPPLSGGSSGLSLSSPQVPGSPFSYPAPSPSLSSGGLPR 1381
++S T P PP SG + PG P S P + + G
Sbjct: 72 ESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPG-PVSSPGRASGTTRPGPLG 130
Query: 1382 TPGRDFSFTPTFSEPSGPLLLPVCPLPTGRRDERSGP---LASPVL--------LETGLP 1430
G S T + L G R + SGP SP + E GLP
Sbjct: 131 QKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLP 190
Query: 1431 LPLPLPLPLP---------------------------------LALPAVLRAQARAPTPL 1457
P P P P L PA R+ + + TPL
Sbjct: 191 RPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPA-SRSLSSSATPL 249
Query: 1458 -PPLLPAPLASCPPPMKRKPGRPRRSPPSMLSLDGPLVRPP---AGAALG---RELLLLP 1510
P P A P P +P+ P + +L P V PP A ALG L P
Sbjct: 250 SSPARSGPSARGTPRAPAHPSQPK--PKGLQALRPPQVTPPRKDAAPALGPLSSSPLATP 307
Query: 1511 G-----QPQT-PVFPSTHDPRTVTLDFRNAGIPAPPPPLPPQ-----PPPPPPPPPVEPT 1559
Q Q P P+T ++T APP P P P PP PP T
Sbjct: 308 SPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATT 367
Query: 1560 KLPFKELDNQWPSEAIPPGPRGRDEVTEEYMELAKSRGPWRRPPKKRHEDLVPPAGSPEL 1619
L L Q +P P A + P + PP PPA SP L
Sbjct: 368 SLGSPTL--QATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPS-------PPA-SPPL 417
Query: 1620 SP 1621
SP
Sbjct: 418 SP 419
Score = 53.9 bits (128), Expect = 1e-06
Identities = 66/247 (26%), Positives = 92/247 (37%), Gaps = 30/247 (12%)
Query: 364 SGPPFK-AQPQDSATFAHTPPPAQATPAPGFKSAFSPYQTPVAHFP------PPPEEPTA 416
+ PP + A+P A A PP QA P+P +P A P PPP+ P
Sbjct: 506 AAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPV 565
Query: 417 TAAFGARDSGEFRRAPAPPPLPPAEPLAKEKPGTPPGPPPPDTNSMELGGRPTFGWSPEP 476
AA PP PPA P + P PP P ++ G R T +P P
Sbjct: 566 LAA----------PLLQVPPSPPASPTLQ----APRRPPTPGPDTSVSGPRLTLALAPGP 611
Query: 477 CDSPGTPTLESSPAGPEKPHDSLDSRI---EMLLKEQRTKLLFLREPDSDTELQMEGSPI 533
P + + S+ +GP+ S + E+ + + P D EL +
Sbjct: 612 -PPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAEL----AAC 666
Query: 534 SSSSSQLSPLAPFGTNSQPGFRGPTPPSSRP-SSTGLEDISPTPLPDSDEDEELDLGLGP 592
++ P P PG P PP++ P S+ GL I T P+S L GP
Sbjct: 667 HPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGP 726
Query: 593 RPPPEPG 599
P G
Sbjct: 727 SPGTSGG 733
Score = 47.0 bits (110), Expect = 2e-04
Identities = 53/200 (26%), Positives = 70/200 (35%), Gaps = 26/200 (13%)
Query: 1197 AVAPEERPSMLDEPPLPVGVEEPAD-SREPPEEPGLSQEGAMLLSPEPPAKEVEARP--- 1252
A P + P L PPL PA + P P S + L +P P A V A P
Sbjct: 513 AKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQ 572
Query: 1253 -PLSPERAPEHDLEVEPEPP----------MMLPLPLQPPLPPPRPPRPPSPPPEPETTD 1301
P SP +P P P + L L PP PP R P P+
Sbjct: 573 VPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHS 632
Query: 1302 ASHPSVPPEPLAEDHPPHTPGLCGSLAKSQSTETVPA--TPGGEPPLSGGSSGLSLSSPQ 1359
+S S P E D P ++ PA + G PPL+ +
Sbjct: 633 SSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGA-------- 684
Query: 1360 VPGSPFSYPAPSPSLSSGGL 1379
PG+P +P + S+ GL
Sbjct: 685 -PGAPLPWPPATGPGSADGL 703
Score = 33.1 bits (74), Expect = 2.7
Identities = 30/107 (28%), Positives = 33/107 (30%), Gaps = 22/107 (20%)
Query: 667 AAVAAPSVLAPTLPLPPPPGFPPLPPPPPPP----------------PPQPGFPMPPPLP 710
AA P+ AP L P PPG P PPP P + G +P
Sbjct: 12 AAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIP 71
Query: 711 PPPPPPPPAHPAVTVPPPPLPAPPG------VPPPPILPPLPPFPPG 751
P P A T P PP PP P P PG
Sbjct: 72 ESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPG 118
>gi|19923202 enhancer of zeste homolog 1 [Homo sapiens]
Length = 747
Score = 102 bits (253), Expect = 5e-21
Identities = 51/124 (41%), Positives = 74/124 (59%), Gaps = 2/124 (1%)
Query: 1783 KKKLKFCKSHIHDWGLFAMEPIAADEMVIEYVGQNIRQVIADMREKRYEDEGIGSSYMFR 1842
KK L S + WG F E + +E + EY G+ I Q AD R K Y+ SS++F
Sbjct: 612 KKHLLLAPSDVAGWGTFIKESVQKNEFISEYCGELISQDEADRRGKVYDK--YMSSFLFN 669
Query: 1843 VDHDTIIDATKCGNFARFINHSCNPNCYAKVITVESQKKIVIYSKQHINVNEEITYDYKF 1902
+++D ++DAT+ GN RF NHS NPNCYAKV+ V +I I++K+ I EE+ +DY++
Sbjct: 670 LNNDFVVDATRKGNKIRFANHSVNPNCYAKVVMVNGDHRIGIFAKRAIQAGEELFFDYRY 729
Query: 1903 PIED 1906
D
Sbjct: 730 SQAD 733
>gi|209862789 microtubule associated monoxygenase, calponin and LIM
domain containing 3 isoform 1 [Homo sapiens]
Length = 2002
Score = 102 bits (253), Expect = 5e-21
Identities = 168/678 (24%), Positives = 245/678 (36%), Gaps = 73/678 (10%)
Query: 975 SGDQKRLRPSTSVDEEDEESERERDRDMADTPCELAKRDPKGVGVRRRPARPLELDSGGE 1034
+G ++ + S+S E +EE E E + L D GV + R L G
Sbjct: 925 TGAEEDVASSSSESEMEEEGEEEEEEP------RLPPSDLGGVPWKEA-VRIHALLKGKS 977
Query: 1035 EDEKESLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDESENDDED-TALSEASEKDEGD 1093
E+E E+ EEEEE EEE EEE+++D D ++ + SE ++ + A++ E
Sbjct: 978 EEELEASKSFGPGNEEEEEEEEEYEEEEEEDYDEEEEESSEAGNQRLQQVMHAADPLEIQ 1037
Query: 1094 SD-------EEETVSIVTSKAEATSSSESSESSEFESSSESSPSSSEDEEEVVAREEEEE 1146
+D E E + +E+++S + ++ E +S P+ E E A E+ +
Sbjct: 1038 ADVHWTHIREREEEERMAPASESSASGAPLDENDLEEDVDSEPAEIEGE----AAEDGDP 1093
Query: 1147 EEEEEMVAEESMASAGPEDFEQDGEEAALAPGAPAVDSLGMEEEVDIETEAVAPEERPSM 1206
+ + ++ S P D +++ A G ++ E+E + E PS
Sbjct: 1094 GDTGAELDDDQHWSDSPSDADRELRLPCPAEGEAELELRVSEDEEKLPASPKHQERGPSQ 1153
Query: 1207 LDEPPLPVGVEEPADSR---EPPEEPGLSQEGAMLLSPEPPAKEVEARP-------PLSP 1256
P + P +S P P S EG L P PA E P PL P
Sbjct: 1154 ATSP-----IRSPQESALLFIPVHSP--STEGPQL--PPVPAATQEKSPEERLFPEPLLP 1204
Query: 1257 ERAPEHDLEVEPEPPMMLPLPLQP-PLPPPRPP-RPPSPPPEPETTDASHPSVPPEPLAE 1314
+ P+ D + + + P+ QP LP R P P SP P+P AS P P P+
Sbjct: 1205 KEKPKADAPSDLK-AVHSPIRSQPVTLPEARTPVSPGSPQPQPPVA-ASTPPPSPLPICS 1262
Query: 1315 DHPPHT----PGLCGSLAKSQSTETVPATPGGEPPLSGGSSGLS-LSSPQVPGSPF--SY 1367
P T P S + Q +TP P+ S L SP S
Sbjct: 1263 QPQPSTEATVPSPTQSPIRFQPAPAKTSTPLAPLPVQSQSDTKDRLGSPLAVDEALRRSD 1322
Query: 1368 PAPSPSLSSGGLPRTPGRDFSFTPTFSEPSGPLLLPVCPLPTGRRDERSGPLASPVLLET 1427
+ S + R+ G TP GP P P P R +
Sbjct: 1323 LVEEFWMKSAEIRRSLG----LTPV-DRSKGP--EPSFPTPAFRPVSLKSYSVEKSPQDE 1375
Query: 1428 GLPLPLPLPLPLPLALPAVLRAQARAPTPLPPLLPAPLASCPPPMKRKPGRPRRSPPSML 1487
GL L PL +P L LP PTP P S + R S S L
Sbjct: 1376 GLHLLKPLSIPKRLGLPKPEGEPLSLPTPRSP-------SDRELRSAQEERRELSSSSGL 1428
Query: 1488 SLDGPLVRPPAGAA----LGRELLLLPGQPQTPVFPSTHDPRTVTLDFRNA--GIPAPPP 1541
L G + +L P P P +P T+ R A PP
Sbjct: 1429 GLHGSSSNMKTLGSQSFNTSDSAMLTPPSSPPPPPPPGEEPATLRRKLREAEPNASVVPP 1488
Query: 1542 PLPP---QPPPPPPPPPVEPTKLPFKELDNQWP-SEAIPPGPRGRDEVTEEYMELAKSRG 1597
PLP +PP P PP E + F E + P ++ + + E + +
Sbjct: 1489 PLPATWMRPPREPAQPPREEVRKSFVESVEEIPFADDVEDTYDDKTEDSSLQEKFFTPPS 1548
Query: 1598 PWRRPPKKRHEDLVPPAG 1615
W RP K RH L G
Sbjct: 1549 CWPRPEKPRHPPLAKENG 1566
Score = 97.1 bits (240), Expect = 2e-19
Identities = 167/624 (26%), Positives = 227/624 (36%), Gaps = 133/624 (21%)
Query: 1029 LDSGGEEDEKESLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDESENDDEDTALSEASE 1088
LD+G EED S SE +E EEE EEEEEE
Sbjct: 923 LDTGAEEDVASSSSE----SEMEEEGEEEEEE-----------------------PRLPP 955
Query: 1089 KDEGDSDEEETVSIVTSKAEATSSSESSESSEFESSSESSPSSSEDEEEVVAREEEEEE- 1147
D G +E V I A +S E E E+S P + E+EEE EEEEEE
Sbjct: 956 SDLGGVPWKEAVRI-----HALLKGKSEE--ELEASKSFGPGNEEEEEEEEEYEEEEEED 1008
Query: 1148 --EEEEMVAE-------ESMASAGPEDFEQD---------GEEAALAP-------GAPAV 1182
EEEE +E + M +A P + + D EE +AP GAP +
Sbjct: 1009 YDEEEEESSEAGNQRLQQVMHAADPLEIQADVHWTHIREREEEERMAPASESSASGAP-L 1067
Query: 1183 DSLGMEEEVDIETEAVAPEERPSMLDEPPLPVGVEEPADSREPPEEPGLSQEGAMLLSPE 1242
D +EE+VD E + E + D P G E D + + P + L P
Sbjct: 1068 DENDLEEDVDSEPAEI---EGEAAEDGDPGDTGAELD-DDQHWSDSPSDADRELRLPCPA 1123
Query: 1243 PPAKEVEARP-------PLSP---ERAPEHDLEV--EPEPPMMLPLPLQPPLPPPRPPRP 1290
E+E R P SP ER P P+ +L +P+ P
Sbjct: 1124 EGEAELELRVSEDEEKLPASPKHQERGPSQATSPIRSPQESALLFIPVHSP-----STEG 1178
Query: 1291 PSPPPEPETTDASHPS--VPPEPLAEDHPPHTPGLCGSLAKSQSTETVPAT-PGGEPPLS 1347
P PP P T P + PEPL P A + P T P P+S
Sbjct: 1179 PQLPPVPAATQEKSPEERLFPEPLLPKEKPKADAPSDLKAVHSPIRSQPVTLPEARTPVS 1238
Query: 1348 GGS----SGLSLSSPQVPGSPF---SYPAPSPSLSSGGLPRTPGRDFSFTPTFSEPSGPL 1400
GS ++ S+P P SP S P PS + ++P R F P ++ S PL
Sbjct: 1239 PGSPQPQPPVAASTP--PPSPLPICSQPQPSTEATVPSPTQSPIR---FQPAPAKTSTPL 1293
Query: 1401 LLPVCPLPTGRRDERSGPLASPVLLETGLPLP--------LPLPLPLPLALPAVLRAQAR 1452
PLP + + L SP+ ++ L + L L V R++
Sbjct: 1294 ----APLPVQSQSDTKDRLGSPLAVDEALRRSDLVEEFWMKSAEIRRSLGLTPVDRSKGP 1349
Query: 1453 APT-PLPPLLPAPLASC---------------PPPMKRKPGRPRRSPPSMLSLDGPLVRP 1496
P+ P P P L S P + ++ G P+ P L P R
Sbjct: 1350 EPSFPTPAFRPVSLKSYSVEKSPQDEGLHLLKPLSIPKRLGLPK---PEGEPLSLPTPRS 1406
Query: 1497 PAGAAL---GRELLLLPGQPQTPVFPSTHDPRTVTLDFRNAGIPAPPPPLPPQPPPPPPP 1553
P+ L E L + S+ + +T+ N A PP PPPPPP
Sbjct: 1407 PSDRELRSAQEERRELSSSSGLGLHGSSSNMKTLGSQSFNTSDSA--MLTPPSSPPPPPP 1464
Query: 1554 PPVEPTKLPFKELDNQWPSEAIPP 1577
P EP L K + + + +PP
Sbjct: 1465 PGEEPATLRRKLREAEPNASVVPP 1488
Score = 56.2 bits (134), Expect = 3e-07
Identities = 102/401 (25%), Positives = 138/401 (34%), Gaps = 84/401 (20%)
Query: 372 PQDSATF---AHTPPPA--QATPAPGFKSAFSPYQTPVAHFPPPPEEPTATAAFGARDSG 426
PQ+SA H+P Q P P SP + P E+P A A +
Sbjct: 1161 PQESALLFIPVHSPSTEGPQLPPVPAATQEKSPEERLFPEPLLPKEKPKADAPSDLKAVH 1220
Query: 427 EFRRAPAPPPLPPAEPLAKEKPGTPPGPPP-----PDTNSMELGGRP---TFGWSPEPCD 478
R+ P LP A PG+P PP P + + + +P T P P
Sbjct: 1221 SPIRSQ-PVTLPEAR--TPVSPGSPQPQPPVAASTPPPSPLPICSQPQPSTEATVPSPTQ 1277
Query: 479 SP----GTPTLESSPAGP---EKPHDSLDSRIEMLLKEQRTKLLFLREPDSDTELQMEGS 531
SP P S+P P + D+ D L ++ LR D E M+ +
Sbjct: 1278 SPIRFQPAPAKTSTPLAPLPVQSQSDTKDRLGSPLAVDEA-----LRRSDLVEEFWMKSA 1332
Query: 532 PISSSSSQLSPLAPFGTNSQPGFRGPTPPSSRPSSTGLEDISPTPLPDSDEDEELDLGLG 591
I S L P + P PTP + RP S + +P +DE L L
Sbjct: 1333 EIRRSLG----LTPVDRSKGPEPSFPTP-AFRPVSLKSYSVEKSP-----QDEGLHLLKP 1382
Query: 592 PRPPPEPGPPDPAGLLSQTAEVALDLVGDRTPTSEKMDEGQQ-------SSGEDMEISDD 644
P G P P G L L R+P+ ++ Q+ SSG + S
Sbjct: 1383 LSIPKRLGLPKPEG-------EPLSLPTPRSPSDRELRSAQEERRELSSSSGLGLHGSSS 1435
Query: 645 EMPSAPITSADCPKPMVVTPGAAAVAAPSVLAPTLPLPPPPGFPPLPPPPPPPPPQPGFP 704
M + S + ++TP P PPPPPPP +
Sbjct: 1436 NMKTLGSQSFNTSDSAMLTP------------------------PSSPPPPPPPGEEPAT 1471
Query: 705 MPPPLPPPPPPPPPAHPAVTVPPPPLPAPPGVPP-PPILPP 744
+ L A P +V PPPLPA PP P PP
Sbjct: 1472 LRRKL-------REAEPNASVVPPPLPATWMRPPREPAQPP 1505
Score = 41.2 bits (95), Expect = 0.010
Identities = 59/251 (23%), Positives = 83/251 (33%), Gaps = 43/251 (17%)
Query: 531 SPISSSSSQLSPL----APFGTNSQPG-FRGPTPPSSRPSSTGLEDISPTPLPDSDEDEE 585
+P S SS+ +PL +S+P G P TG E DS D +
Sbjct: 1055 APASESSASGAPLDENDLEEDVDSEPAEIEGEAAEDGDPGDTGAELDDDQHWSDSPSDAD 1114
Query: 586 LDLGLG--------------------PRPPP--EPGPPDPAGLLSQTAEVALDLVGDRTP 623
+L L P P E GP + E AL + +P
Sbjct: 1115 RELRLPCPAEGEAELELRVSEDEEKLPASPKHQERGPSQATSPIRSPQESALLFIPVHSP 1174
Query: 624 TSEKMDEGQQSSGEDMEISDDEMPSAPITSADCPKPMVVTPGAAAVAAPSVLAPTLPLPP 683
++E + + ++ + P+ + PK + AV +P + P+
Sbjct: 1175 STEGPQLPPVPAATQEKSPEERLFPEPLLPKEKPKADAPSD-LKAVHSP---IRSQPVTL 1230
Query: 684 PPGFPPLPPPPPPPPPQPGFPMPPPLPPPPPPPPPAHPAVTVPPP--------PLPAPPG 735
P P+ P P P P PPP P P P TVP P P PA
Sbjct: 1231 PEARTPVSPGSPQPQPPVAASTPPPSPLPICSQPQPSTEATVPSPTQSPIRFQPAPAKTS 1290
Query: 736 VPPPPILPPLP 746
P L PLP
Sbjct: 1291 TP----LAPLP 1297
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 101 bits (252), Expect = 6e-21
Identities = 146/657 (22%), Positives = 225/657 (34%), Gaps = 82/657 (12%)
Query: 968 EPPDTTSSGDQKRL--RPSTSVDEEDEESERERDRDMADTPCELAKRDPKGVGVRRRPAR 1025
E +TT++ Q + T+ +E + E+ +D+A T LAK PK + PA
Sbjct: 151 ETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPAL 210
Query: 1026 PLELDSGGEEDEKESLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDESENDDEDTALSE 1085
+ +E T +E A +E S E T +
Sbjct: 211 --------------TTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAP 256
Query: 1086 ASEKDEGDSDEEETVSIVTSKAEATSSSESSESSEFESSSESSPSSSEDEEEVVAREEEE 1145
+ K+ + +E + T++ E + ++ ++S+P++ ++ ++
Sbjct: 257 TTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTT-----TKSAPTTPKEPAPTTPKKPAP 311
Query: 1146 EEEEEEMVAEESMASAGPEDFEQDGEEAALAPGAPAVDSLGMEEEVDIETEAVAPEERPS 1205
+E A P+ E P PA + E AP++
Sbjct: 312 TTPKEP-------APTTPK------EPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAP 358
Query: 1206 MLDEPPLPVGVEEPADS--REP----PEEPG-LSQEGAMLLSPEPPAKEVEARPPLSPER 1258
+ P P +EPA + +EP P+EP + + A + EP ++ P E
Sbjct: 359 TTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEP 418
Query: 1259 APEHDLEVEPEPPMMLPLPLQPPLPPPRPPRPPSPP----PEPETTDASHPSVPPEPLAE 1314
+P E P P P P P P P P+ P+P P P TT P+ P EP
Sbjct: 419 SPTTTKEPAPTTPKE-PAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPT 477
Query: 1315 DHPPHTPGLCGSLAKSQSTETVPATPGGEPPLSGGSSGLSLSSPQVPGSPFSYPAPSPSL 1374
P L + + P TP E P L+ ++P+ P +P + P+P+
Sbjct: 478 TPKETAPTTPKKLTPTTPEKLAPTTP--EKPAPTTPEELAPTTPEEP-TPTTPEEPAPTT 534
Query: 1375 SSGGLPRTPGRDFSFTPTFSEPSGPLL-LPVCPLPTGRRDERSGPLASPVLLETGLPLPL 1433
P TP TP P+ P P P T + +P L+ P
Sbjct: 535 PKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKG---TAPTTLKEPAPTTP 591
Query: 1434 PLPLPLPLAL-----PAVLRAQARAPT------PLPPLLPAPLASCPPPMKRKPGRPRRS 1482
P P LA P APT P P PAP P + P P+ +
Sbjct: 592 KKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTT----PKEPAPTTPKGT 647
Query: 1483 PPSMLSLDGPLV-RPPAGAALGRELLLLP----GQPQTPVFPSTHDPRTVTLDFRNAGIP 1537
P+ L P + PA L P P P P T P
Sbjct: 648 APTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTT--P 705
Query: 1538 APPPPLPPQPPPP------PPPPPVEPTKLPFKELDNQWPSEAIPPGPRGRDEVTEE 1588
P P P+ PPP P EPT + K D P + P P+ + +E
Sbjct: 706 KKPAPTTPETPPPTTSEVSTPTTTKEPTTI-HKSPDESTPELSAEPTPKALENSPKE 761
Score = 95.9 bits (237), Expect = 3e-19
Identities = 158/721 (21%), Positives = 240/721 (33%), Gaps = 117/721 (16%)
Query: 960 PSFKVKRKEPPDTTSSGDQKRLRPSTSVDEE-----DEESERERDRDMADTPCELAKRDP 1014
P ++ E D + +K+ P V +E D + D + T P
Sbjct: 57 PDYESFCAEVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSP 116
Query: 1015 KGVGVRRRPARPLELDSGGEEDEKESLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDES 1074
K + RP L + ++ SL+ +E+T E +E ++ +D ++++
Sbjct: 117 KITTAKPINPRP-SLPPNSDTSKETSLTVNKETTVETKETTTTNKQTS-----TDGKEKT 170
Query: 1075 ENDDEDTALSEASEKDEGDSDEEETVSIVTSKAEATSSSESSESSEFESSSESSPSSSED 1134
+ E ++ + S KD + + ++ T KAE T+ + + E +P++ ++
Sbjct: 171 TSAKETQSIEKTSAKDLAPTSK--VLAKPTPKAETTTKGPA-----LTTPKEPTPTTPKE 223
Query: 1135 EEEVVAREEEEEEEEEEMVAEESMASAGPEDFEQDGEEAALAPGAPAVDSLGMEEEVDIE 1194
+E ++ SA E AP P +E
Sbjct: 224 PASTTPKEP----------TPTTIKSAPTTPKEPAPTTTKSAPTTP-------KEPAPTT 266
Query: 1195 TEAVAPEERPSMLDEPPLPVGVEEPADSREP-----PEEPGLSQEGAMLLSPEPPAKEVE 1249
T+ AP + P P +EPA + P+EP + +P+ PA
Sbjct: 267 TKEPAPTT-----PKEPAPTTTKEPAPTTTKSAPTTPKEPAPT-------TPKKPAPTTP 314
Query: 1250 ARPPLSPERAPEHDLEVEPEPPMMLPLPLQPPLPPPRPPRPPSP------------PPEP 1297
P + + P EP P P P P P P P+ P+P P P
Sbjct: 315 KEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAP 374
Query: 1298 ETTDASHPSVPPEP---LAEDHPPHTPGLCGSLAKSQST-----------ETVPATPGGE 1343
TT P+ P EP + P T + KS T E P TP
Sbjct: 375 TTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEP 434
Query: 1344 PPLSGGSSGLSLSSPQVPGSPFSYPAPSPSLSSGGLPRTPGRDFSFTPTFSEPSGP-LLL 1402
P + + P +P P+P+ + P TP TP + P+ P L
Sbjct: 435 APTTPKKPAPTTPKEPAPTTP---KEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLT 491
Query: 1403 PVCP---LPTGRRDERSGPLASPVLLET--GLPLPLPLPLPLPLALPAVLRAQARAPTPL 1457
P P PT E+ P L T P P P P A + P P
Sbjct: 492 PTTPEKLAPT--TPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPT 549
Query: 1458 PPLLPAPLASCPP----PMKRKPGRPRRSPPSMLSLDGPLV-RPPAGAALGRELLLLPGQ 1512
P PAP P P + P P+ + P+ L P + PA L P
Sbjct: 550 TPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELA------PTT 603
Query: 1513 PQTPVFPSTHDPRTVTLDFRNAGIPAPPPPLPPQPPPPPPPPPVEPTKL--PFKELDNQ- 1569
+ P + P T P P P P+ P P P PT L P +
Sbjct: 604 TKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKP 663
Query: 1570 WPSEAIPPGPRGRDEVTEEY------MELAKS--RGPWRRPPKKRHEDLVPPAGSPELSP 1621
P E P +G T + E A + + P PKK P +PE P
Sbjct: 664 APKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKK------PAPTTPETPP 717
Query: 1622 P 1622
P
Sbjct: 718 P 718
Score = 92.0 bits (227), Expect = 5e-18
Identities = 134/556 (24%), Positives = 184/556 (33%), Gaps = 90/556 (16%)
Query: 253 SQDTAYSSCRLDTPNSYGQGTPLTPRLGTPFS-------QDSSYSSRQPTPSYLFS---- 301
++D A +S L P + T P L TP + +S + ++PTP+ + S
Sbjct: 184 AKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTT 243
Query: 302 -QDPA-VTFKARRHESKFTDAYNRRHEHHYVHNSPAVTAVAG-ATAAFRGSSDLPFGAVG 358
++PA T K+ K + PA T A + + P
Sbjct: 244 PKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAP 303
Query: 359 GTGGSSGPPFKAQPQDSATFAHTPP----PAQATPAPGFKSAFSPYQT-PVAHFPPPPEE 413
T P +P + TP PA T P + P T P P P+E
Sbjct: 304 TTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKE 363
Query: 414 PTATAAFGARDSGEFRRAPAPP-PLPPAEPLAKEKPGTPPGPPPPDTNSMELGGRPTFGW 472
P T + + P+P P PA K P T P P T S PT
Sbjct: 364 PAPTTP--KEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSA-----PTTPK 416
Query: 473 SPEPCDS----PGTPTLESSPAGPEKPHDSLDSRIEMLLKEQRTKLLFLREPDSDTELQM 528
P P + P TP E +P P+KP + ++ ++P T +
Sbjct: 417 EPSPTTTKEPAPTTPK-EPAPTTPKKPAPTTPKEPAPTTPKEPAPTT-TKKPAPTTPKE- 473
Query: 529 EGSPISSSSSQLSPLAPFG-TNSQPGFRGPTPPSSRPSSTGLEDISPT----PLPDSDED 583
P ++ + +P P T + P PT P +P+ T E+++PT P P + E+
Sbjct: 474 ---PAPTTPKETAPTTPKKLTPTTPEKLAPTTPE-KPAPTTPEELAPTTPEEPTPTTPEE 529
Query: 584 EE--LDLGLGPRPPPEPGPPDPAGLLSQTAEVALDLVGDRTPTSEKMDEGQQSSGEDMEI 641
P P EP P P E A + PT+ K G
Sbjct: 530 PAPTTPKAAAPNTPKEPAPTTPK-------EPAPTTPKEPAPTTPKETAPTTPKGTAPTT 582
Query: 642 SDDEMPSAPI---------------TSADCPKPMVVTPGAAAVAAPSVLAPTLPLPPPPG 686
+ P+ P TS C KP TP A P APT P P P
Sbjct: 583 LKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPT 642
Query: 687 FP----------PLPPPPPPPPPQPGFPM-------------PPPLPPPPPPPPPAHPAV 723
P P P P P P+ P P P P P PA
Sbjct: 643 TPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAP 702
Query: 724 TVPPPPLPAPPGVPPP 739
T P P P P PPP
Sbjct: 703 TTPKKPAPTTPETPPP 718
Score = 82.8 bits (203), Expect = 3e-15
Identities = 119/581 (20%), Positives = 178/581 (30%), Gaps = 82/581 (14%)
Query: 1066 DDSDDRDESENDDEDTALSEA-SEKDEGDSDEEETVSIVTSKAEATSSSESSESSEFESS 1124
D+ +R + + + + EA S D GD + T + ++S + + +
Sbjct: 68 DNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPR 127
Query: 1125 SESSPSSSEDEEEVVAREEEEEEEEEEMVAEESMASAGPEDFEQDGEEAALAPGAPAVDS 1184
P+S +E + +E E +E S ++ +E A D
Sbjct: 128 PSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDL 187
Query: 1185 LGMEEEVDIETEAVAPEERPSMLDEP--PLPVGVEEPADS--REP-----------PEEP 1229
+ + T + L P P P +EPA + +EP P+EP
Sbjct: 188 APTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEP 247
Query: 1230 GLSQEGAMLLSPEPPAKEVEARPPLSPERAPEHDLEVEPEPPMMLPLPLQPPLPPPRPPR 1289
+ + +P+ PA P + + P EP P P P P P P+
Sbjct: 248 APTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPK 307
Query: 1290 PPSPP----PEPETTDASHPSVP--PEPLAEDHPPHTPGLCGSLAKSQSTETVPATPGGE 1343
P+P P P T P+ P P P ++ P TP A + T P P
Sbjct: 308 KPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPT 367
Query: 1344 PPLSGGSSGLSLSSPQVPGSPFSYPAPSPSLSSGGLPRTPGRDFSFTPTFSEPSGPLLLP 1403
P + SP P P AP+ + S+ + P T T S P+ P
Sbjct: 368 TPKEPAPTTTKEPSPTTPKEP----APTTTKSAPTTTKEPAP----TTTKSAPTTPKE-- 417
Query: 1404 VCPLPTGRRDERSGPLASPVLLETGLPLPLPLPLPLPLALPAVLRAQARAPTPLPPLLPA 1463
P PT ++ P P + P P P PA
Sbjct: 418 --PSPTTTKE------------------------PAPTT--------PKEPAPTTPKKPA 443
Query: 1464 PLASCPPPMKRKPGRPRRSPPSMLSLDGPLVRPPAGAALGRELLLLPGQPQTPVFPSTHD 1523
P P + P P+ P+ P +E + TP P
Sbjct: 444 PTT----PKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLA 499
Query: 1524 PRTVTLDFRNAGIPAPPPPLPPQPPPPPPPPPVEPTKLPFKELDNQWPSEAIPPGPRGRD 1583
P T P P P P P P EPT +E P A P P+
Sbjct: 500 PTT------------PEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPA 547
Query: 1584 EVTEEYMELAKSRGPWRRPPKKRHEDLVPPAGSPELSPPQP 1624
T + + P PK+ L P P
Sbjct: 548 PTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAP 588
Score = 72.0 bits (175), Expect = 5e-12
Identities = 113/515 (21%), Positives = 174/515 (33%), Gaps = 59/515 (11%)
Query: 240 SSSVTPNSGGTPFSQDTAYSSCRLDTPNSYGQGTPLTPRLGTPFSQDSSYSS-RQPTPSY 298
S+ TP + A ++ + P + + TP TP+ P +++ + ++ ++P P+
Sbjct: 293 SAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTA 352
Query: 299 LFSQDPAVTFKARRHESKFTDAYNRRHEHHYVHNSPAVTAVAGATAAFRGSSDLPFGAVG 358
P + K + PA T A + +
Sbjct: 353 PKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAP------- 405
Query: 359 GTGGSSGPPFKAQPQDSATFAHTPPPAQATPAPGFKSAFSPYQTPVAHFPPPPEEPTATA 418
T S P +P + T P PAP +P TP P P+EP T
Sbjct: 406 -TTTKSAPTTPKEPSPTTT-KEPAPTTPKEPAPTTPKKPAP-TTPKEPAPTTPKEPAPTT 462
Query: 419 AFGARDSGEFRRAPAPPPLPPAEPLAKEKPGTPPGPPPPDTNSMELGGRPTFGWSPEPCD 478
P P P EP T P P T + PT P P
Sbjct: 463 T------------KKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTT 510
Query: 479 ----SPGTPTLESSPAGPEKPHDSLDSRIEMLLKEQRTKLLFLREPDSDTELQMEGSPIS 534
+P TP E +P PE+P + ++ +EP T + P
Sbjct: 511 PEELAPTTPE-EPTPTTPEEPAPTTPKAAAPNTPKEPAPTT-PKEPAPTTPKE----PAP 564
Query: 535 SSSSQLSPLAPFGTNSQPGFRGPTPPSSRPSSTGLEDISPTPL--PDSDEDEE----LDL 588
++ + +P P GT + + P P + P ++++PT P S ++
Sbjct: 565 TTPKETAPTTPKGT-APTTLKEPAPTT--PKKPAPKELAPTTTKEPTSTTCDKPAPTTPK 621
Query: 589 GLGPRPPPEPGPPDPAGLLSQTAE-VALDLVGDRTPTSEKMDEGQQSSGEDMEISDDEMP 647
G P P EP P P T + A + + PT+ K + + +++ + + P
Sbjct: 622 GTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPK-----KPAPKELAPTTTKGP 676
Query: 648 SAPITSADCPKPMVVTPGAAAVAAPSVLAPTLPLPPPPGFPPLPPPPPPPPPQPGFPMPP 707
TS KP TP A P APT P P P P PPP P P
Sbjct: 677 ----TSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEP 732
Query: 708 PLPPPPPPPPPAHPAVTVPPPP-----LPAPPGVP 737
P + P ++ P P P PGVP
Sbjct: 733 --TTIHKSPDESTPELSAEPTPKALENSPKEPGVP 765
Score = 53.5 bits (127), Expect = 2e-06
Identities = 50/199 (25%), Positives = 66/199 (33%), Gaps = 23/199 (11%)
Query: 561 SSRPSSTGLEDISPTPL--PDSDEDEELDLGLGPRPPPEPGPPDPAGLLSQTAEVALDLV 618
S+ P T + I+P P P+SD +E L + E T E
Sbjct: 113 STSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVE------------TKETTTTNK 160
Query: 619 GDRTPTSEKMDEGQQSSGEDMEISDDEMPSAPITSADCPKPMVVTPGAAAVAAPSVLAPT 678
T EK +++ + + D P++ + + PK T G A + P PT
Sbjct: 161 QTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPA-LTTPKEPTPT 219
Query: 679 LPLPPPPGFPPLPPPPP--PPPPQPGFPMP------PPLPPPPPPPPPAHPAVTVPPPPL 730
P P P P P P P P P P P P P PA T P P
Sbjct: 220 TPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPA 279
Query: 731 PAPPGVPPPPILPPLPPFP 749
P P P P P
Sbjct: 280 PTTTKEPAPTTTKSAPTTP 298
Score = 37.7 bits (86), Expect = 0.11
Identities = 75/395 (18%), Positives = 126/395 (31%), Gaps = 36/395 (9%)
Query: 967 KEPPDTTSSGDQKRLRPSTSVDEEDEESERERDRDMADTPCELAKRDPKGVGVRRRPARP 1026
KEP TT + E + + TP E A PK P P
Sbjct: 432 KEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETA----PTTP 487
Query: 1027 LELDSGGEEDEKESLSEEQESTEEEEEAEEEEEEED----DDDDDSDDRDESENDDEDTA 1082
+L E + E+ T EE A EE ++ + + + N ++ A
Sbjct: 488 KKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPA 547
Query: 1083 LSEASEKDEGDSDEEETVSIVTSKAEATSSSESSESSEFESSSESSPSSSEDEEEVVARE 1142
+ K+ + +E T K A ++ + + + + + ++P +E
Sbjct: 548 --PTTPKEPAPTTPKEPAP-TTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTT 604
Query: 1143 EEEEEEEEEMVAEESMASAGPEDFEQDG-----EEAALAPGAPAVDSLGMEEEVDIETEA 1197
+E + A + P ++ E A P A +L +E +
Sbjct: 605 KEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTL--KEPAPTTPKK 662
Query: 1198 VAPEERPSMLDEPPLPVGVEEPADSREPPEEPGLSQEGAMLLSPEPPAKEVEARP-PLSP 1256
AP+E + P ++PA + P +P+ PA +P P +P
Sbjct: 663 PAPKELAPTTTKGPTSTTSDKPAPTTPKETAP---------TTPKEPAPTTPKKPAPTTP 713
Query: 1257 ERAPEHDLEVEPEPPMMLPLPLQPPLPPPRPPRPPSPPPEPETTDASHPSVPPEPLAEDH 1316
E P EV P + P P P+ P VP
Sbjct: 714 ETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVP----TTKT 769
Query: 1317 PPHTPGLCGSLAKSQSTE----TVPATPGGEPPLS 1347
P T + AK ++TE T P T P ++
Sbjct: 770 PAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMT 804
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 101 bits (252), Expect = 6e-21
Identities = 146/657 (22%), Positives = 225/657 (34%), Gaps = 82/657 (12%)
Query: 968 EPPDTTSSGDQKRL--RPSTSVDEEDEESERERDRDMADTPCELAKRDPKGVGVRRRPAR 1025
E +TT++ Q + T+ +E + E+ +D+A T LAK PK + PA
Sbjct: 192 ETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPAL 251
Query: 1026 PLELDSGGEEDEKESLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDESENDDEDTALSE 1085
+ +E T +E A +E S E T +
Sbjct: 252 --------------TTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAP 297
Query: 1086 ASEKDEGDSDEEETVSIVTSKAEATSSSESSESSEFESSSESSPSSSEDEEEVVAREEEE 1145
+ K+ + +E + T++ E + ++ ++S+P++ ++ ++
Sbjct: 298 TTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTT-----TKSAPTTPKEPAPTTPKKPAP 352
Query: 1146 EEEEEEMVAEESMASAGPEDFEQDGEEAALAPGAPAVDSLGMEEEVDIETEAVAPEERPS 1205
+E A P+ E P PA + E AP++
Sbjct: 353 TTPKEP-------APTTPK------EPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAP 399
Query: 1206 MLDEPPLPVGVEEPADS--REP----PEEPG-LSQEGAMLLSPEPPAKEVEARPPLSPER 1258
+ P P +EPA + +EP P+EP + + A + EP ++ P E
Sbjct: 400 TTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEP 459
Query: 1259 APEHDLEVEPEPPMMLPLPLQPPLPPPRPPRPPSPP----PEPETTDASHPSVPPEPLAE 1314
+P E P P P P P P P P+ P+P P P TT P+ P EP
Sbjct: 460 SPTTTKEPAPTTPKE-PAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPT 518
Query: 1315 DHPPHTPGLCGSLAKSQSTETVPATPGGEPPLSGGSSGLSLSSPQVPGSPFSYPAPSPSL 1374
P L + + P TP E P L+ ++P+ P +P + P+P+
Sbjct: 519 TPKETAPTTPKKLTPTTPEKLAPTTP--EKPAPTTPEELAPTTPEEP-TPTTPEEPAPTT 575
Query: 1375 SSGGLPRTPGRDFSFTPTFSEPSGPLL-LPVCPLPTGRRDERSGPLASPVLLETGLPLPL 1433
P TP TP P+ P P P T + +P L+ P
Sbjct: 576 PKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKG---TAPTTLKEPAPTTP 632
Query: 1434 PLPLPLPLAL-----PAVLRAQARAPT------PLPPLLPAPLASCPPPMKRKPGRPRRS 1482
P P LA P APT P P PAP P + P P+ +
Sbjct: 633 KKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTT----PKEPAPTTPKGT 688
Query: 1483 PPSMLSLDGPLV-RPPAGAALGRELLLLP----GQPQTPVFPSTHDPRTVTLDFRNAGIP 1537
P+ L P + PA L P P P P T P
Sbjct: 689 APTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTT--P 746
Query: 1538 APPPPLPPQPPPP------PPPPPVEPTKLPFKELDNQWPSEAIPPGPRGRDEVTEE 1588
P P P+ PPP P EPT + K D P + P P+ + +E
Sbjct: 747 KKPAPTTPETPPPTTSEVSTPTTTKEPTTI-HKSPDESTPELSAEPTPKALENSPKE 802
Score = 95.9 bits (237), Expect = 3e-19
Identities = 158/721 (21%), Positives = 240/721 (33%), Gaps = 117/721 (16%)
Query: 960 PSFKVKRKEPPDTTSSGDQKRLRPSTSVDEE-----DEESERERDRDMADTPCELAKRDP 1014
P ++ E D + +K+ P V +E D + D + T P
Sbjct: 98 PDYESFCAEVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSP 157
Query: 1015 KGVGVRRRPARPLELDSGGEEDEKESLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDES 1074
K + RP L + ++ SL+ +E+T E +E ++ +D ++++
Sbjct: 158 KITTAKPINPRP-SLPPNSDTSKETSLTVNKETTVETKETTTTNKQTS-----TDGKEKT 211
Query: 1075 ENDDEDTALSEASEKDEGDSDEEETVSIVTSKAEATSSSESSESSEFESSSESSPSSSED 1134
+ E ++ + S KD + + ++ T KAE T+ + + E +P++ ++
Sbjct: 212 TSAKETQSIEKTSAKDLAPTSK--VLAKPTPKAETTTKGPA-----LTTPKEPTPTTPKE 264
Query: 1135 EEEVVAREEEEEEEEEEMVAEESMASAGPEDFEQDGEEAALAPGAPAVDSLGMEEEVDIE 1194
+E ++ SA E AP P +E
Sbjct: 265 PASTTPKEP----------TPTTIKSAPTTPKEPAPTTTKSAPTTP-------KEPAPTT 307
Query: 1195 TEAVAPEERPSMLDEPPLPVGVEEPADSREP-----PEEPGLSQEGAMLLSPEPPAKEVE 1249
T+ AP + P P +EPA + P+EP + +P+ PA
Sbjct: 308 TKEPAPTT-----PKEPAPTTTKEPAPTTTKSAPTTPKEPAPT-------TPKKPAPTTP 355
Query: 1250 ARPPLSPERAPEHDLEVEPEPPMMLPLPLQPPLPPPRPPRPPSP------------PPEP 1297
P + + P EP P P P P P P P+ P+P P P
Sbjct: 356 KEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAP 415
Query: 1298 ETTDASHPSVPPEP---LAEDHPPHTPGLCGSLAKSQST-----------ETVPATPGGE 1343
TT P+ P EP + P T + KS T E P TP
Sbjct: 416 TTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEP 475
Query: 1344 PPLSGGSSGLSLSSPQVPGSPFSYPAPSPSLSSGGLPRTPGRDFSFTPTFSEPSGP-LLL 1402
P + + P +P P+P+ + P TP TP + P+ P L
Sbjct: 476 APTTPKKPAPTTPKEPAPTTP---KEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLT 532
Query: 1403 PVCP---LPTGRRDERSGPLASPVLLET--GLPLPLPLPLPLPLALPAVLRAQARAPTPL 1457
P P PT E+ P L T P P P P A + P P
Sbjct: 533 PTTPEKLAPT--TPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPT 590
Query: 1458 PPLLPAPLASCPP----PMKRKPGRPRRSPPSMLSLDGPLV-RPPAGAALGRELLLLPGQ 1512
P PAP P P + P P+ + P+ L P + PA L P
Sbjct: 591 TPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELA------PTT 644
Query: 1513 PQTPVFPSTHDPRTVTLDFRNAGIPAPPPPLPPQPPPPPPPPPVEPTKL--PFKELDNQ- 1569
+ P + P T P P P P+ P P P PT L P +
Sbjct: 645 TKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKP 704
Query: 1570 WPSEAIPPGPRGRDEVTEEY------MELAKS--RGPWRRPPKKRHEDLVPPAGSPELSP 1621
P E P +G T + E A + + P PKK P +PE P
Sbjct: 705 APKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKK------PAPTTPETPP 758
Query: 1622 P 1622
P
Sbjct: 759 P 759
Score = 92.0 bits (227), Expect = 5e-18
Identities = 134/556 (24%), Positives = 184/556 (33%), Gaps = 90/556 (16%)
Query: 253 SQDTAYSSCRLDTPNSYGQGTPLTPRLGTPFS-------QDSSYSSRQPTPSYLFS---- 301
++D A +S L P + T P L TP + +S + ++PTP+ + S
Sbjct: 225 AKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTT 284
Query: 302 -QDPA-VTFKARRHESKFTDAYNRRHEHHYVHNSPAVTAVAG-ATAAFRGSSDLPFGAVG 358
++PA T K+ K + PA T A + + P
Sbjct: 285 PKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAP 344
Query: 359 GTGGSSGPPFKAQPQDSATFAHTPP----PAQATPAPGFKSAFSPYQT-PVAHFPPPPEE 413
T P +P + TP PA T P + P T P P P+E
Sbjct: 345 TTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKE 404
Query: 414 PTATAAFGARDSGEFRRAPAPP-PLPPAEPLAKEKPGTPPGPPPPDTNSMELGGRPTFGW 472
P T + + P+P P PA K P T P P T S PT
Sbjct: 405 PAPTTP--KEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSA-----PTTPK 457
Query: 473 SPEPCDS----PGTPTLESSPAGPEKPHDSLDSRIEMLLKEQRTKLLFLREPDSDTELQM 528
P P + P TP E +P P+KP + ++ ++P T +
Sbjct: 458 EPSPTTTKEPAPTTPK-EPAPTTPKKPAPTTPKEPAPTTPKEPAPTT-TKKPAPTTPKE- 514
Query: 529 EGSPISSSSSQLSPLAPFG-TNSQPGFRGPTPPSSRPSSTGLEDISPT----PLPDSDED 583
P ++ + +P P T + P PT P +P+ T E+++PT P P + E+
Sbjct: 515 ---PAPTTPKETAPTTPKKLTPTTPEKLAPTTPE-KPAPTTPEELAPTTPEEPTPTTPEE 570
Query: 584 EE--LDLGLGPRPPPEPGPPDPAGLLSQTAEVALDLVGDRTPTSEKMDEGQQSSGEDMEI 641
P P EP P P E A + PT+ K G
Sbjct: 571 PAPTTPKAAAPNTPKEPAPTTPK-------EPAPTTPKEPAPTTPKETAPTTPKGTAPTT 623
Query: 642 SDDEMPSAPI---------------TSADCPKPMVVTPGAAAVAAPSVLAPTLPLPPPPG 686
+ P+ P TS C KP TP A P APT P P P
Sbjct: 624 LKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPT 683
Query: 687 FP----------PLPPPPPPPPPQPGFPM-------------PPPLPPPPPPPPPAHPAV 723
P P P P P P+ P P P P P PA
Sbjct: 684 TPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAP 743
Query: 724 TVPPPPLPAPPGVPPP 739
T P P P P PPP
Sbjct: 744 TTPKKPAPTTPETPPP 759
Score = 82.8 bits (203), Expect = 3e-15
Identities = 119/581 (20%), Positives = 178/581 (30%), Gaps = 82/581 (14%)
Query: 1066 DDSDDRDESENDDEDTALSEA-SEKDEGDSDEEETVSIVTSKAEATSSSESSESSEFESS 1124
D+ +R + + + + EA S D GD + T + ++S + + +
Sbjct: 109 DNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPR 168
Query: 1125 SESSPSSSEDEEEVVAREEEEEEEEEEMVAEESMASAGPEDFEQDGEEAALAPGAPAVDS 1184
P+S +E + +E E +E S ++ +E A D
Sbjct: 169 PSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDL 228
Query: 1185 LGMEEEVDIETEAVAPEERPSMLDEP--PLPVGVEEPADS--REP-----------PEEP 1229
+ + T + L P P P +EPA + +EP P+EP
Sbjct: 229 APTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEP 288
Query: 1230 GLSQEGAMLLSPEPPAKEVEARPPLSPERAPEHDLEVEPEPPMMLPLPLQPPLPPPRPPR 1289
+ + +P+ PA P + + P EP P P P P P P+
Sbjct: 289 APTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPK 348
Query: 1290 PPSPP----PEPETTDASHPSVP--PEPLAEDHPPHTPGLCGSLAKSQSTETVPATPGGE 1343
P+P P P T P+ P P P ++ P TP A + T P P
Sbjct: 349 KPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPT 408
Query: 1344 PPLSGGSSGLSLSSPQVPGSPFSYPAPSPSLSSGGLPRTPGRDFSFTPTFSEPSGPLLLP 1403
P + SP P P AP+ + S+ + P T T S P+ P
Sbjct: 409 TPKEPAPTTTKEPSPTTPKEP----APTTTKSAPTTTKEPAP----TTTKSAPTTPKE-- 458
Query: 1404 VCPLPTGRRDERSGPLASPVLLETGLPLPLPLPLPLPLALPAVLRAQARAPTPLPPLLPA 1463
P PT ++ P P + P P P PA
Sbjct: 459 --PSPTTTKE------------------------PAPTT--------PKEPAPTTPKKPA 484
Query: 1464 PLASCPPPMKRKPGRPRRSPPSMLSLDGPLVRPPAGAALGRELLLLPGQPQTPVFPSTHD 1523
P P + P P+ P+ P +E + TP P
Sbjct: 485 PTT----PKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLA 540
Query: 1524 PRTVTLDFRNAGIPAPPPPLPPQPPPPPPPPPVEPTKLPFKELDNQWPSEAIPPGPRGRD 1583
P T P P P P P P EPT +E P A P P+
Sbjct: 541 PTT------------PEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPA 588
Query: 1584 EVTEEYMELAKSRGPWRRPPKKRHEDLVPPAGSPELSPPQP 1624
T + + P PK+ L P P
Sbjct: 589 PTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAP 629
Score = 72.0 bits (175), Expect = 5e-12
Identities = 113/515 (21%), Positives = 174/515 (33%), Gaps = 59/515 (11%)
Query: 240 SSSVTPNSGGTPFSQDTAYSSCRLDTPNSYGQGTPLTPRLGTPFSQDSSYSS-RQPTPSY 298
S+ TP + A ++ + P + + TP TP+ P +++ + ++ ++P P+
Sbjct: 334 SAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTA 393
Query: 299 LFSQDPAVTFKARRHESKFTDAYNRRHEHHYVHNSPAVTAVAGATAAFRGSSDLPFGAVG 358
P + K + PA T A + +
Sbjct: 394 PKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAP------- 446
Query: 359 GTGGSSGPPFKAQPQDSATFAHTPPPAQATPAPGFKSAFSPYQTPVAHFPPPPEEPTATA 418
T S P +P + T P PAP +P TP P P+EP T
Sbjct: 447 -TTTKSAPTTPKEPSPTTT-KEPAPTTPKEPAPTTPKKPAP-TTPKEPAPTTPKEPAPTT 503
Query: 419 AFGARDSGEFRRAPAPPPLPPAEPLAKEKPGTPPGPPPPDTNSMELGGRPTFGWSPEPCD 478
P P P EP T P P T + PT P P
Sbjct: 504 T------------KKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTT 551
Query: 479 ----SPGTPTLESSPAGPEKPHDSLDSRIEMLLKEQRTKLLFLREPDSDTELQMEGSPIS 534
+P TP E +P PE+P + ++ +EP T + P
Sbjct: 552 PEELAPTTPE-EPTPTTPEEPAPTTPKAAAPNTPKEPAPTT-PKEPAPTTPKE----PAP 605
Query: 535 SSSSQLSPLAPFGTNSQPGFRGPTPPSSRPSSTGLEDISPTPL--PDSDEDEE----LDL 588
++ + +P P GT + + P P + P ++++PT P S ++
Sbjct: 606 TTPKETAPTTPKGT-APTTLKEPAPTT--PKKPAPKELAPTTTKEPTSTTCDKPAPTTPK 662
Query: 589 GLGPRPPPEPGPPDPAGLLSQTAE-VALDLVGDRTPTSEKMDEGQQSSGEDMEISDDEMP 647
G P P EP P P T + A + + PT+ K + + +++ + + P
Sbjct: 663 GTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPK-----KPAPKELAPTTTKGP 717
Query: 648 SAPITSADCPKPMVVTPGAAAVAAPSVLAPTLPLPPPPGFPPLPPPPPPPPPQPGFPMPP 707
TS KP TP A P APT P P P P PPP P P
Sbjct: 718 ----TSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEP 773
Query: 708 PLPPPPPPPPPAHPAVTVPPPP-----LPAPPGVP 737
P + P ++ P P P PGVP
Sbjct: 774 --TTIHKSPDESTPELSAEPTPKALENSPKEPGVP 806
Score = 53.5 bits (127), Expect = 2e-06
Identities = 50/199 (25%), Positives = 66/199 (33%), Gaps = 23/199 (11%)
Query: 561 SSRPSSTGLEDISPTPL--PDSDEDEELDLGLGPRPPPEPGPPDPAGLLSQTAEVALDLV 618
S+ P T + I+P P P+SD +E L + E T E
Sbjct: 154 STSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVE------------TKETTTTNK 201
Query: 619 GDRTPTSEKMDEGQQSSGEDMEISDDEMPSAPITSADCPKPMVVTPGAAAVAAPSVLAPT 678
T EK +++ + + D P++ + + PK T G A + P PT
Sbjct: 202 QTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPA-LTTPKEPTPT 260
Query: 679 LPLPPPPGFPPLPPPPP--PPPPQPGFPMP------PPLPPPPPPPPPAHPAVTVPPPPL 730
P P P P P P P P P P P P P PA T P P
Sbjct: 261 TPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPA 320
Query: 731 PAPPGVPPPPILPPLPPFP 749
P P P P P
Sbjct: 321 PTTTKEPAPTTTKSAPTTP 339
Score = 37.7 bits (86), Expect = 0.11
Identities = 75/395 (18%), Positives = 126/395 (31%), Gaps = 36/395 (9%)
Query: 967 KEPPDTTSSGDQKRLRPSTSVDEEDEESERERDRDMADTPCELAKRDPKGVGVRRRPARP 1026
KEP TT + E + + TP E A PK P P
Sbjct: 473 KEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETA----PTTP 528
Query: 1027 LELDSGGEEDEKESLSEEQESTEEEEEAEEEEEEED----DDDDDSDDRDESENDDEDTA 1082
+L E + E+ T EE A EE ++ + + + N ++ A
Sbjct: 529 KKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPA 588
Query: 1083 LSEASEKDEGDSDEEETVSIVTSKAEATSSSESSESSEFESSSESSPSSSEDEEEVVARE 1142
+ K+ + +E T K A ++ + + + + + ++P +E
Sbjct: 589 --PTTPKEPAPTTPKEPAP-TTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTT 645
Query: 1143 EEEEEEEEEMVAEESMASAGPEDFEQDG-----EEAALAPGAPAVDSLGMEEEVDIETEA 1197
+E + A + P ++ E A P A +L +E +
Sbjct: 646 KEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTL--KEPAPTTPKK 703
Query: 1198 VAPEERPSMLDEPPLPVGVEEPADSREPPEEPGLSQEGAMLLSPEPPAKEVEARP-PLSP 1256
AP+E + P ++PA + P +P+ PA +P P +P
Sbjct: 704 PAPKELAPTTTKGPTSTTSDKPAPTTPKETAP---------TTPKEPAPTTPKKPAPTTP 754
Query: 1257 ERAPEHDLEVEPEPPMMLPLPLQPPLPPPRPPRPPSPPPEPETTDASHPSVPPEPLAEDH 1316
E P EV P + P P P+ P VP
Sbjct: 755 ETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVP----TTKT 810
Query: 1317 PPHTPGLCGSLAKSQSTE----TVPATPGGEPPLS 1347
P T + AK ++TE T P T P ++
Sbjct: 811 PAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMT 845
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 101 bits (252), Expect = 6e-21
Identities = 146/657 (22%), Positives = 225/657 (34%), Gaps = 82/657 (12%)
Query: 968 EPPDTTSSGDQKRL--RPSTSVDEEDEESERERDRDMADTPCELAKRDPKGVGVRRRPAR 1025
E +TT++ Q + T+ +E + E+ +D+A T LAK PK + PA
Sbjct: 244 ETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPAL 303
Query: 1026 PLELDSGGEEDEKESLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDESENDDEDTALSE 1085
+ +E T +E A +E S E T +
Sbjct: 304 --------------TTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAP 349
Query: 1086 ASEKDEGDSDEEETVSIVTSKAEATSSSESSESSEFESSSESSPSSSEDEEEVVAREEEE 1145
+ K+ + +E + T++ E + ++ ++S+P++ ++ ++
Sbjct: 350 TTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTT-----TKSAPTTPKEPAPTTPKKPAP 404
Query: 1146 EEEEEEMVAEESMASAGPEDFEQDGEEAALAPGAPAVDSLGMEEEVDIETEAVAPEERPS 1205
+E A P+ E P PA + E AP++
Sbjct: 405 TTPKEP-------APTTPK------EPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAP 451
Query: 1206 MLDEPPLPVGVEEPADS--REP----PEEPG-LSQEGAMLLSPEPPAKEVEARPPLSPER 1258
+ P P +EPA + +EP P+EP + + A + EP ++ P E
Sbjct: 452 TTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEP 511
Query: 1259 APEHDLEVEPEPPMMLPLPLQPPLPPPRPPRPPSPP----PEPETTDASHPSVPPEPLAE 1314
+P E P P P P P P P P+ P+P P P TT P+ P EP
Sbjct: 512 SPTTTKEPAPTTPKE-PAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPT 570
Query: 1315 DHPPHTPGLCGSLAKSQSTETVPATPGGEPPLSGGSSGLSLSSPQVPGSPFSYPAPSPSL 1374
P L + + P TP E P L+ ++P+ P +P + P+P+
Sbjct: 571 TPKETAPTTPKKLTPTTPEKLAPTTP--EKPAPTTPEELAPTTPEEP-TPTTPEEPAPTT 627
Query: 1375 SSGGLPRTPGRDFSFTPTFSEPSGPLL-LPVCPLPTGRRDERSGPLASPVLLETGLPLPL 1433
P TP TP P+ P P P T + +P L+ P
Sbjct: 628 PKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKG---TAPTTLKEPAPTTP 684
Query: 1434 PLPLPLPLAL-----PAVLRAQARAPT------PLPPLLPAPLASCPPPMKRKPGRPRRS 1482
P P LA P APT P P PAP P + P P+ +
Sbjct: 685 KKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTT----PKEPAPTTPKGT 740
Query: 1483 PPSMLSLDGPLV-RPPAGAALGRELLLLP----GQPQTPVFPSTHDPRTVTLDFRNAGIP 1537
P+ L P + PA L P P P P T P
Sbjct: 741 APTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTT--P 798
Query: 1538 APPPPLPPQPPPP------PPPPPVEPTKLPFKELDNQWPSEAIPPGPRGRDEVTEE 1588
P P P+ PPP P EPT + K D P + P P+ + +E
Sbjct: 799 KKPAPTTPETPPPTTSEVSTPTTTKEPTTI-HKSPDESTPELSAEPTPKALENSPKE 854
Score = 95.5 bits (236), Expect = 4e-19
Identities = 157/701 (22%), Positives = 236/701 (33%), Gaps = 129/701 (18%)
Query: 975 SGDQKRLRPSTSVDEEDEESERERDRDMADTPCELAKRDPKGVGVRRRPARPLELDSGGE 1034
+GD K P TS + ++ S T ++ P + RP+ P D+ E
Sbjct: 187 NGDFKVTTPDTSTTQHNKVS----------TSPKITTAKP----INPRPSLPPNSDTSKE 232
Query: 1035 EDEKESLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDESENDDEDTALSEASEKDEGDS 1094
SL+ +E+T E +E ++ +D ++++ + E ++ + S KD +
Sbjct: 233 T----SLTVNKETTVETKETTTTNKQTS-----TDGKEKTTSAKETQSIEKTSAKDLAPT 283
Query: 1095 DEEETVSIVTSKAEATSSSESSESSEFESSSESSPSSSEDEEEVVAREEEEEEEEEEMVA 1154
+ ++ T KAE T+ + + E +P++ ++ +E
Sbjct: 284 SK--VLAKPTPKAETTTKGPA-----LTTPKEPTPTTPKEPASTTPKEP----------T 326
Query: 1155 EESMASAGPEDFEQDGEEAALAPGAPAVDSLGMEEEVDIETEAVAPEERPSMLDEPPLPV 1214
++ SA E AP P +E T+ AP + P P
Sbjct: 327 PTTIKSAPTTPKEPAPTTTKSAPTTP-------KEPAPTTTKEPAPTT-----PKEPAPT 374
Query: 1215 GVEEPADSREP-----PEEPGLSQEGAMLLSPEPPAKEVEARPPLSPERAPEHDLEVEPE 1269
+EPA + P+EP + +P+ PA P + + P EP
Sbjct: 375 TTKEPAPTTTKSAPTTPKEPAPT-------TPKKPAPTTPKEPAPTTPKEPTPTTPKEPA 427
Query: 1270 PPMMLPLPLQPPLPPPRPPRPPSP------------PPEPETTDASHPSVPPEP---LAE 1314
P P P P P P P+ P+P P P TT P+ P EP +
Sbjct: 428 PTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTK 487
Query: 1315 DHPPHTPGLCGSLAKSQST-----------ETVPATPGGEPPLSGGSSGLSLSSPQVPGS 1363
P T + KS T E P TP P + + P +
Sbjct: 488 SAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTT 547
Query: 1364 PFSYPAPSPSLSSGGLPRTPGRDFSFTPTFSEPSGP-LLLPVCP---LPTGRRDERSGPL 1419
P P+P+ + P TP TP + P+ P L P P PT E+ P
Sbjct: 548 P---KEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPT--TPEKPAPT 602
Query: 1420 ASPVLLET--GLPLPLPLPLPLPLALPAVLRAQARAPTPLPPLLPAPLASCPP----PMK 1473
L T P P P P A + P P P PAP P P +
Sbjct: 603 TPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKE 662
Query: 1474 RKPGRPRRSPPSMLSLDGPLV-RPPAGAALGRELLLLPGQPQTPVFPSTHDPRTVTLDFR 1532
P P+ + P+ L P + PA L P + P + P T
Sbjct: 663 TAPTTPKGTAPTTLKEPAPTTPKKPAPKELA------PTTTKEPTSTTCDKPAPTTPKGT 716
Query: 1533 NAGIPAPPPPLPPQPPPPPPPPPVEPTKL--PFKELDNQ-WPSEAIPPGPRGRDEVTEEY 1589
P P P P+ P P P PT L P + P E P +G T +
Sbjct: 717 APTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDK 776
Query: 1590 ------MELAKS--RGPWRRPPKKRHEDLVPPAGSPELSPP 1622
E A + + P PKK P +PE PP
Sbjct: 777 PAPTTPKETAPTTPKEPAPTTPKK------PAPTTPETPPP 811
Score = 92.0 bits (227), Expect = 5e-18
Identities = 134/556 (24%), Positives = 184/556 (33%), Gaps = 90/556 (16%)
Query: 253 SQDTAYSSCRLDTPNSYGQGTPLTPRLGTPFS-------QDSSYSSRQPTPSYLFS---- 301
++D A +S L P + T P L TP + +S + ++PTP+ + S
Sbjct: 277 AKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTT 336
Query: 302 -QDPA-VTFKARRHESKFTDAYNRRHEHHYVHNSPAVTAVAG-ATAAFRGSSDLPFGAVG 358
++PA T K+ K + PA T A + + P
Sbjct: 337 PKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAP 396
Query: 359 GTGGSSGPPFKAQPQDSATFAHTPP----PAQATPAPGFKSAFSPYQT-PVAHFPPPPEE 413
T P +P + TP PA T P + P T P P P+E
Sbjct: 397 TTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKE 456
Query: 414 PTATAAFGARDSGEFRRAPAPP-PLPPAEPLAKEKPGTPPGPPPPDTNSMELGGRPTFGW 472
P T + + P+P P PA K P T P P T S PT
Sbjct: 457 PAPTTP--KEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSA-----PTTPK 509
Query: 473 SPEPCDS----PGTPTLESSPAGPEKPHDSLDSRIEMLLKEQRTKLLFLREPDSDTELQM 528
P P + P TP E +P P+KP + ++ ++P T +
Sbjct: 510 EPSPTTTKEPAPTTPK-EPAPTTPKKPAPTTPKEPAPTTPKEPAPTT-TKKPAPTTPKE- 566
Query: 529 EGSPISSSSSQLSPLAPFG-TNSQPGFRGPTPPSSRPSSTGLEDISPT----PLPDSDED 583
P ++ + +P P T + P PT P +P+ T E+++PT P P + E+
Sbjct: 567 ---PAPTTPKETAPTTPKKLTPTTPEKLAPTTPE-KPAPTTPEELAPTTPEEPTPTTPEE 622
Query: 584 EE--LDLGLGPRPPPEPGPPDPAGLLSQTAEVALDLVGDRTPTSEKMDEGQQSSGEDMEI 641
P P EP P P E A + PT+ K G
Sbjct: 623 PAPTTPKAAAPNTPKEPAPTTPK-------EPAPTTPKEPAPTTPKETAPTTPKGTAPTT 675
Query: 642 SDDEMPSAPI---------------TSADCPKPMVVTPGAAAVAAPSVLAPTLPLPPPPG 686
+ P+ P TS C KP TP A P APT P P P
Sbjct: 676 LKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPT 735
Query: 687 FP----------PLPPPPPPPPPQPGFPM-------------PPPLPPPPPPPPPAHPAV 723
P P P P P P+ P P P P P PA
Sbjct: 736 TPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAP 795
Query: 724 TVPPPPLPAPPGVPPP 739
T P P P P PPP
Sbjct: 796 TTPKKPAPTTPETPPP 811
Score = 87.4 bits (215), Expect = 1e-16
Identities = 134/653 (20%), Positives = 205/653 (31%), Gaps = 103/653 (15%)
Query: 1011 KRDPKGVGVRRRPARPLELDSGGEEDEKESLSEEQESTEEEEE----------------- 1053
KR PK +++ + +E + E E+ S+SE QES+
Sbjct: 93 KRSPKPPN-KKKTKKVIESE---EITEEHSVSENQESSSSSSSSSSSSTIRKIKSSKNSA 148
Query: 1054 AEEEEEEEDDDDDDSDDRDESENDDEDTALSEA-SEKDEGDSDEEETVSIVTSKAEATSS 1112
A E +++ D+ +R + + + + EA S D GD + T + ++S
Sbjct: 149 ANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTS 208
Query: 1113 SESSESSEFESSSESSPSSSEDEEEVVAREEEEEEEEEEMVAEESMASAGPEDFEQDGEE 1172
+ + + P+S +E + +E E +E S ++ +E
Sbjct: 209 PKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKE 268
Query: 1173 AALAPGAPAVDSLGMEEEVDIETEAVAPEERPSMLDEP--PLPVGVEEPADS--REP--- 1225
A D + + T + L P P P +EPA + +EP
Sbjct: 269 TQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPT 328
Query: 1226 --------PEEPGLSQEGAMLLSPEPPAKEVEARPPLSPERAPEHDLEVEPEPPMMLPLP 1277
P+EP + + +P+ PA P + + P EP P P
Sbjct: 329 TIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAP 388
Query: 1278 LQPPLPPPRPPRPPSPP----PEPETTDASHPSVP--PEPLAEDHPPHTPGLCGSLAKSQ 1331
P P P P+ P+P P P T P+ P P P ++ P TP A +
Sbjct: 389 TTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKK 448
Query: 1332 STETVPATPGGEPPLSGGSSGLSLSSPQVPGSPFSYPAPSPSLSSGGLPRTPGRDFSFTP 1391
T P P P + SP P P AP+ + S+ + P T
Sbjct: 449 PAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEP----APTTTKSAPTTTKEPAP----TT 500
Query: 1392 TFSEPSGPLLLPVCPLPTGRRDERSGPLASPVLLETGLPLPLPLPLPLPLALPAVLRAQA 1451
T S P+ P P PT ++ P P
Sbjct: 501 TKSAPTTPKE----PSPTTTKE------------------------PAPTT--------P 524
Query: 1452 RAPTPLPPLLPAPLASCPPPMKRKPGRPRRSPPSMLSLDGPLVRPPAGAALGRELLLLPG 1511
+ P P P PAP P + P P+ P+ P +E
Sbjct: 525 KEPAPTTPKKPAPTT----PKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTP 580
Query: 1512 QPQTPVFPSTHDPRTVTLDFRNAGIPAPPPPLPPQPPPPPPPPPVEPTKLPFKELDNQWP 1571
+ TP P P T P P P P P P EPT +E P
Sbjct: 581 KKLTPTTPEKLAPTT------------PEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTP 628
Query: 1572 SEAIPPGPRGRDEVTEEYMELAKSRGPWRRPPKKRHEDLVPPAGSPELSPPQP 1624
A P P+ T + + P PK+ L P P
Sbjct: 629 KAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAP 681
Score = 72.0 bits (175), Expect = 5e-12
Identities = 113/515 (21%), Positives = 174/515 (33%), Gaps = 59/515 (11%)
Query: 240 SSSVTPNSGGTPFSQDTAYSSCRLDTPNSYGQGTPLTPRLGTPFSQDSSYSS-RQPTPSY 298
S+ TP + A ++ + P + + TP TP+ P +++ + ++ ++P P+
Sbjct: 386 SAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTA 445
Query: 299 LFSQDPAVTFKARRHESKFTDAYNRRHEHHYVHNSPAVTAVAGATAAFRGSSDLPFGAVG 358
P + K + PA T A + +
Sbjct: 446 PKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAP------- 498
Query: 359 GTGGSSGPPFKAQPQDSATFAHTPPPAQATPAPGFKSAFSPYQTPVAHFPPPPEEPTATA 418
T S P +P + T P PAP +P TP P P+EP T
Sbjct: 499 -TTTKSAPTTPKEPSPTTT-KEPAPTTPKEPAPTTPKKPAP-TTPKEPAPTTPKEPAPTT 555
Query: 419 AFGARDSGEFRRAPAPPPLPPAEPLAKEKPGTPPGPPPPDTNSMELGGRPTFGWSPEPCD 478
P P P EP T P P T + PT P P
Sbjct: 556 T------------KKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTT 603
Query: 479 ----SPGTPTLESSPAGPEKPHDSLDSRIEMLLKEQRTKLLFLREPDSDTELQMEGSPIS 534
+P TP E +P PE+P + ++ +EP T + P
Sbjct: 604 PEELAPTTPE-EPTPTTPEEPAPTTPKAAAPNTPKEPAPTT-PKEPAPTTPKE----PAP 657
Query: 535 SSSSQLSPLAPFGTNSQPGFRGPTPPSSRPSSTGLEDISPTPL--PDSDEDEE----LDL 588
++ + +P P GT + + P P + P ++++PT P S ++
Sbjct: 658 TTPKETAPTTPKGT-APTTLKEPAPTT--PKKPAPKELAPTTTKEPTSTTCDKPAPTTPK 714
Query: 589 GLGPRPPPEPGPPDPAGLLSQTAE-VALDLVGDRTPTSEKMDEGQQSSGEDMEISDDEMP 647
G P P EP P P T + A + + PT+ K + + +++ + + P
Sbjct: 715 GTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPK-----KPAPKELAPTTTKGP 769
Query: 648 SAPITSADCPKPMVVTPGAAAVAAPSVLAPTLPLPPPPGFPPLPPPPPPPPPQPGFPMPP 707
TS KP TP A P APT P P P P PPP P P
Sbjct: 770 ----TSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEP 825
Query: 708 PLPPPPPPPPPAHPAVTVPPPP-----LPAPPGVP 737
P + P ++ P P P PGVP
Sbjct: 826 --TTIHKSPDESTPELSAEPTPKALENSPKEPGVP 858
Score = 53.5 bits (127), Expect = 2e-06
Identities = 50/199 (25%), Positives = 66/199 (33%), Gaps = 23/199 (11%)
Query: 561 SSRPSSTGLEDISPTPL--PDSDEDEELDLGLGPRPPPEPGPPDPAGLLSQTAEVALDLV 618
S+ P T + I+P P P+SD +E L + E T E
Sbjct: 206 STSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVE------------TKETTTTNK 253
Query: 619 GDRTPTSEKMDEGQQSSGEDMEISDDEMPSAPITSADCPKPMVVTPGAAAVAAPSVLAPT 678
T EK +++ + + D P++ + + PK T G A + P PT
Sbjct: 254 QTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPA-LTTPKEPTPT 312
Query: 679 LPLPPPPGFPPLPPPPP--PPPPQPGFPMP------PPLPPPPPPPPPAHPAVTVPPPPL 730
P P P P P P P P P P P P P PA T P P
Sbjct: 313 TPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPA 372
Query: 731 PAPPGVPPPPILPPLPPFP 749
P P P P P
Sbjct: 373 PTTTKEPAPTTTKSAPTTP 391
Score = 37.7 bits (86), Expect = 0.11
Identities = 75/395 (18%), Positives = 126/395 (31%), Gaps = 36/395 (9%)
Query: 967 KEPPDTTSSGDQKRLRPSTSVDEEDEESERERDRDMADTPCELAKRDPKGVGVRRRPARP 1026
KEP TT + E + + TP E A PK P P
Sbjct: 525 KEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETA----PTTP 580
Query: 1027 LELDSGGEEDEKESLSEEQESTEEEEEAEEEEEEED----DDDDDSDDRDESENDDEDTA 1082
+L E + E+ T EE A EE ++ + + + N ++ A
Sbjct: 581 KKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPA 640
Query: 1083 LSEASEKDEGDSDEEETVSIVTSKAEATSSSESSESSEFESSSESSPSSSEDEEEVVARE 1142
+ K+ + +E T K A ++ + + + + + ++P +E
Sbjct: 641 --PTTPKEPAPTTPKEPAP-TTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTT 697
Query: 1143 EEEEEEEEEMVAEESMASAGPEDFEQDG-----EEAALAPGAPAVDSLGMEEEVDIETEA 1197
+E + A + P ++ E A P A +L +E +
Sbjct: 698 KEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTL--KEPAPTTPKK 755
Query: 1198 VAPEERPSMLDEPPLPVGVEEPADSREPPEEPGLSQEGAMLLSPEPPAKEVEARP-PLSP 1256
AP+E + P ++PA + P +P+ PA +P P +P
Sbjct: 756 PAPKELAPTTTKGPTSTTSDKPAPTTPKETAP---------TTPKEPAPTTPKKPAPTTP 806
Query: 1257 ERAPEHDLEVEPEPPMMLPLPLQPPLPPPRPPRPPSPPPEPETTDASHPSVPPEPLAEDH 1316
E P EV P + P P P+ P VP
Sbjct: 807 ETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVP----TTKT 862
Query: 1317 PPHTPGLCGSLAKSQSTE----TVPATPGGEPPLS 1347
P T + AK ++TE T P T P ++
Sbjct: 863 PAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMT 897
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 101 bits (252), Expect = 6e-21
Identities = 146/657 (22%), Positives = 225/657 (34%), Gaps = 82/657 (12%)
Query: 968 EPPDTTSSGDQKRL--RPSTSVDEEDEESERERDRDMADTPCELAKRDPKGVGVRRRPAR 1025
E +TT++ Q + T+ +E + E+ +D+A T LAK PK + PA
Sbjct: 285 ETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPAL 344
Query: 1026 PLELDSGGEEDEKESLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDESENDDEDTALSE 1085
+ +E T +E A +E S E T +
Sbjct: 345 --------------TTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAP 390
Query: 1086 ASEKDEGDSDEEETVSIVTSKAEATSSSESSESSEFESSSESSPSSSEDEEEVVAREEEE 1145
+ K+ + +E + T++ E + ++ ++S+P++ ++ ++
Sbjct: 391 TTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTT-----TKSAPTTPKEPAPTTPKKPAP 445
Query: 1146 EEEEEEMVAEESMASAGPEDFEQDGEEAALAPGAPAVDSLGMEEEVDIETEAVAPEERPS 1205
+E A P+ E P PA + E AP++
Sbjct: 446 TTPKEP-------APTTPK------EPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAP 492
Query: 1206 MLDEPPLPVGVEEPADS--REP----PEEPG-LSQEGAMLLSPEPPAKEVEARPPLSPER 1258
+ P P +EPA + +EP P+EP + + A + EP ++ P E
Sbjct: 493 TTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEP 552
Query: 1259 APEHDLEVEPEPPMMLPLPLQPPLPPPRPPRPPSPP----PEPETTDASHPSVPPEPLAE 1314
+P E P P P P P P P P+ P+P P P TT P+ P EP
Sbjct: 553 SPTTTKEPAPTTPKE-PAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPT 611
Query: 1315 DHPPHTPGLCGSLAKSQSTETVPATPGGEPPLSGGSSGLSLSSPQVPGSPFSYPAPSPSL 1374
P L + + P TP E P L+ ++P+ P +P + P+P+
Sbjct: 612 TPKETAPTTPKKLTPTTPEKLAPTTP--EKPAPTTPEELAPTTPEEP-TPTTPEEPAPTT 668
Query: 1375 SSGGLPRTPGRDFSFTPTFSEPSGPLL-LPVCPLPTGRRDERSGPLASPVLLETGLPLPL 1433
P TP TP P+ P P P T + +P L+ P
Sbjct: 669 PKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKG---TAPTTLKEPAPTTP 725
Query: 1434 PLPLPLPLAL-----PAVLRAQARAPT------PLPPLLPAPLASCPPPMKRKPGRPRRS 1482
P P LA P APT P P PAP P + P P+ +
Sbjct: 726 KKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTT----PKEPAPTTPKGT 781
Query: 1483 PPSMLSLDGPLV-RPPAGAALGRELLLLP----GQPQTPVFPSTHDPRTVTLDFRNAGIP 1537
P+ L P + PA L P P P P T P
Sbjct: 782 APTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTT--P 839
Query: 1538 APPPPLPPQPPPP------PPPPPVEPTKLPFKELDNQWPSEAIPPGPRGRDEVTEE 1588
P P P+ PPP P EPT + K D P + P P+ + +E
Sbjct: 840 KKPAPTTPETPPPTTSEVSTPTTTKEPTTI-HKSPDESTPELSAEPTPKALENSPKE 895
Score = 95.5 bits (236), Expect = 4e-19
Identities = 157/701 (22%), Positives = 236/701 (33%), Gaps = 129/701 (18%)
Query: 975 SGDQKRLRPSTSVDEEDEESERERDRDMADTPCELAKRDPKGVGVRRRPARPLELDSGGE 1034
+GD K P TS + ++ S T ++ P + RP+ P D+ E
Sbjct: 228 NGDFKVTTPDTSTTQHNKVS----------TSPKITTAKP----INPRPSLPPNSDTSKE 273
Query: 1035 EDEKESLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDESENDDEDTALSEASEKDEGDS 1094
SL+ +E+T E +E ++ +D ++++ + E ++ + S KD +
Sbjct: 274 T----SLTVNKETTVETKETTTTNKQTS-----TDGKEKTTSAKETQSIEKTSAKDLAPT 324
Query: 1095 DEEETVSIVTSKAEATSSSESSESSEFESSSESSPSSSEDEEEVVAREEEEEEEEEEMVA 1154
+ ++ T KAE T+ + + E +P++ ++ +E
Sbjct: 325 SK--VLAKPTPKAETTTKGPA-----LTTPKEPTPTTPKEPASTTPKEP----------T 367
Query: 1155 EESMASAGPEDFEQDGEEAALAPGAPAVDSLGMEEEVDIETEAVAPEERPSMLDEPPLPV 1214
++ SA E AP P +E T+ AP + P P
Sbjct: 368 PTTIKSAPTTPKEPAPTTTKSAPTTP-------KEPAPTTTKEPAPTT-----PKEPAPT 415
Query: 1215 GVEEPADSREP-----PEEPGLSQEGAMLLSPEPPAKEVEARPPLSPERAPEHDLEVEPE 1269
+EPA + P+EP + +P+ PA P + + P EP
Sbjct: 416 TTKEPAPTTTKSAPTTPKEPAPT-------TPKKPAPTTPKEPAPTTPKEPTPTTPKEPA 468
Query: 1270 PPMMLPLPLQPPLPPPRPPRPPSP------------PPEPETTDASHPSVPPEP---LAE 1314
P P P P P P P+ P+P P P TT P+ P EP +
Sbjct: 469 PTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTK 528
Query: 1315 DHPPHTPGLCGSLAKSQST-----------ETVPATPGGEPPLSGGSSGLSLSSPQVPGS 1363
P T + KS T E P TP P + + P +
Sbjct: 529 SAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTT 588
Query: 1364 PFSYPAPSPSLSSGGLPRTPGRDFSFTPTFSEPSGP-LLLPVCP---LPTGRRDERSGPL 1419
P P+P+ + P TP TP + P+ P L P P PT E+ P
Sbjct: 589 P---KEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPT--TPEKPAPT 643
Query: 1420 ASPVLLET--GLPLPLPLPLPLPLALPAVLRAQARAPTPLPPLLPAPLASCPP----PMK 1473
L T P P P P A + P P P PAP P P +
Sbjct: 644 TPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKE 703
Query: 1474 RKPGRPRRSPPSMLSLDGPLV-RPPAGAALGRELLLLPGQPQTPVFPSTHDPRTVTLDFR 1532
P P+ + P+ L P + PA L P + P + P T
Sbjct: 704 TAPTTPKGTAPTTLKEPAPTTPKKPAPKELA------PTTTKEPTSTTCDKPAPTTPKGT 757
Query: 1533 NAGIPAPPPPLPPQPPPPPPPPPVEPTKL--PFKELDNQ-WPSEAIPPGPRGRDEVTEEY 1589
P P P P+ P P P PT L P + P E P +G T +
Sbjct: 758 APTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDK 817
Query: 1590 ------MELAKS--RGPWRRPPKKRHEDLVPPAGSPELSPP 1622
E A + + P PKK P +PE PP
Sbjct: 818 PAPTTPKETAPTTPKEPAPTTPKK------PAPTTPETPPP 852
Score = 92.0 bits (227), Expect = 5e-18
Identities = 134/556 (24%), Positives = 184/556 (33%), Gaps = 90/556 (16%)
Query: 253 SQDTAYSSCRLDTPNSYGQGTPLTPRLGTPFS-------QDSSYSSRQPTPSYLFS---- 301
++D A +S L P + T P L TP + +S + ++PTP+ + S
Sbjct: 318 AKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTT 377
Query: 302 -QDPA-VTFKARRHESKFTDAYNRRHEHHYVHNSPAVTAVAG-ATAAFRGSSDLPFGAVG 358
++PA T K+ K + PA T A + + P
Sbjct: 378 PKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAP 437
Query: 359 GTGGSSGPPFKAQPQDSATFAHTPP----PAQATPAPGFKSAFSPYQT-PVAHFPPPPEE 413
T P +P + TP PA T P + P T P P P+E
Sbjct: 438 TTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKE 497
Query: 414 PTATAAFGARDSGEFRRAPAPP-PLPPAEPLAKEKPGTPPGPPPPDTNSMELGGRPTFGW 472
P T + + P+P P PA K P T P P T S PT
Sbjct: 498 PAPTTP--KEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSA-----PTTPK 550
Query: 473 SPEPCDS----PGTPTLESSPAGPEKPHDSLDSRIEMLLKEQRTKLLFLREPDSDTELQM 528
P P + P TP E +P P+KP + ++ ++P T +
Sbjct: 551 EPSPTTTKEPAPTTPK-EPAPTTPKKPAPTTPKEPAPTTPKEPAPTT-TKKPAPTTPKE- 607
Query: 529 EGSPISSSSSQLSPLAPFG-TNSQPGFRGPTPPSSRPSSTGLEDISPT----PLPDSDED 583
P ++ + +P P T + P PT P +P+ T E+++PT P P + E+
Sbjct: 608 ---PAPTTPKETAPTTPKKLTPTTPEKLAPTTPE-KPAPTTPEELAPTTPEEPTPTTPEE 663
Query: 584 EE--LDLGLGPRPPPEPGPPDPAGLLSQTAEVALDLVGDRTPTSEKMDEGQQSSGEDMEI 641
P P EP P P E A + PT+ K G
Sbjct: 664 PAPTTPKAAAPNTPKEPAPTTPK-------EPAPTTPKEPAPTTPKETAPTTPKGTAPTT 716
Query: 642 SDDEMPSAPI---------------TSADCPKPMVVTPGAAAVAAPSVLAPTLPLPPPPG 686
+ P+ P TS C KP TP A P APT P P P
Sbjct: 717 LKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPT 776
Query: 687 FP----------PLPPPPPPPPPQPGFPM-------------PPPLPPPPPPPPPAHPAV 723
P P P P P P+ P P P P P PA
Sbjct: 777 TPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAP 836
Query: 724 TVPPPPLPAPPGVPPP 739
T P P P P PPP
Sbjct: 837 TTPKKPAPTTPETPPP 852
Score = 87.4 bits (215), Expect = 1e-16
Identities = 134/653 (20%), Positives = 205/653 (31%), Gaps = 103/653 (15%)
Query: 1011 KRDPKGVGVRRRPARPLELDSGGEEDEKESLSEEQESTEEEEE----------------- 1053
KR PK +++ + +E + E E+ S+SE QES+
Sbjct: 134 KRSPKPPN-KKKTKKVIESE---EITEEHSVSENQESSSSSSSSSSSSTIRKIKSSKNSA 189
Query: 1054 AEEEEEEEDDDDDDSDDRDESENDDEDTALSEA-SEKDEGDSDEEETVSIVTSKAEATSS 1112
A E +++ D+ +R + + + + EA S D GD + T + ++S
Sbjct: 190 ANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTS 249
Query: 1113 SESSESSEFESSSESSPSSSEDEEEVVAREEEEEEEEEEMVAEESMASAGPEDFEQDGEE 1172
+ + + P+S +E + +E E +E S ++ +E
Sbjct: 250 PKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKE 309
Query: 1173 AALAPGAPAVDSLGMEEEVDIETEAVAPEERPSMLDEP--PLPVGVEEPADS--REP--- 1225
A D + + T + L P P P +EPA + +EP
Sbjct: 310 TQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPT 369
Query: 1226 --------PEEPGLSQEGAMLLSPEPPAKEVEARPPLSPERAPEHDLEVEPEPPMMLPLP 1277
P+EP + + +P+ PA P + + P EP P P
Sbjct: 370 TIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAP 429
Query: 1278 LQPPLPPPRPPRPPSPP----PEPETTDASHPSVP--PEPLAEDHPPHTPGLCGSLAKSQ 1331
P P P P+ P+P P P T P+ P P P ++ P TP A +
Sbjct: 430 TTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKK 489
Query: 1332 STETVPATPGGEPPLSGGSSGLSLSSPQVPGSPFSYPAPSPSLSSGGLPRTPGRDFSFTP 1391
T P P P + SP P P AP+ + S+ + P T
Sbjct: 490 PAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEP----APTTTKSAPTTTKEPAP----TT 541
Query: 1392 TFSEPSGPLLLPVCPLPTGRRDERSGPLASPVLLETGLPLPLPLPLPLPLALPAVLRAQA 1451
T S P+ P P PT ++ P P
Sbjct: 542 TKSAPTTPKE----PSPTTTKE------------------------PAPTT--------P 565
Query: 1452 RAPTPLPPLLPAPLASCPPPMKRKPGRPRRSPPSMLSLDGPLVRPPAGAALGRELLLLPG 1511
+ P P P PAP P + P P+ P+ P +E
Sbjct: 566 KEPAPTTPKKPAPTT----PKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTP 621
Query: 1512 QPQTPVFPSTHDPRTVTLDFRNAGIPAPPPPLPPQPPPPPPPPPVEPTKLPFKELDNQWP 1571
+ TP P P T P P P P P P EPT +E P
Sbjct: 622 KKLTPTTPEKLAPTT------------PEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTP 669
Query: 1572 SEAIPPGPRGRDEVTEEYMELAKSRGPWRRPPKKRHEDLVPPAGSPELSPPQP 1624
A P P+ T + + P PK+ L P P
Sbjct: 670 KAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAP 722
Score = 72.0 bits (175), Expect = 5e-12
Identities = 113/515 (21%), Positives = 174/515 (33%), Gaps = 59/515 (11%)
Query: 240 SSSVTPNSGGTPFSQDTAYSSCRLDTPNSYGQGTPLTPRLGTPFSQDSSYSS-RQPTPSY 298
S+ TP + A ++ + P + + TP TP+ P +++ + ++ ++P P+
Sbjct: 427 SAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTA 486
Query: 299 LFSQDPAVTFKARRHESKFTDAYNRRHEHHYVHNSPAVTAVAGATAAFRGSSDLPFGAVG 358
P + K + PA T A + +
Sbjct: 487 PKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAP------- 539
Query: 359 GTGGSSGPPFKAQPQDSATFAHTPPPAQATPAPGFKSAFSPYQTPVAHFPPPPEEPTATA 418
T S P +P + T P PAP +P TP P P+EP T
Sbjct: 540 -TTTKSAPTTPKEPSPTTT-KEPAPTTPKEPAPTTPKKPAP-TTPKEPAPTTPKEPAPTT 596
Query: 419 AFGARDSGEFRRAPAPPPLPPAEPLAKEKPGTPPGPPPPDTNSMELGGRPTFGWSPEPCD 478
P P P EP T P P T + PT P P
Sbjct: 597 T------------KKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTT 644
Query: 479 ----SPGTPTLESSPAGPEKPHDSLDSRIEMLLKEQRTKLLFLREPDSDTELQMEGSPIS 534
+P TP E +P PE+P + ++ +EP T + P
Sbjct: 645 PEELAPTTPE-EPTPTTPEEPAPTTPKAAAPNTPKEPAPTT-PKEPAPTTPKE----PAP 698
Query: 535 SSSSQLSPLAPFGTNSQPGFRGPTPPSSRPSSTGLEDISPTPL--PDSDEDEE----LDL 588
++ + +P P GT + + P P + P ++++PT P S ++
Sbjct: 699 TTPKETAPTTPKGT-APTTLKEPAPTT--PKKPAPKELAPTTTKEPTSTTCDKPAPTTPK 755
Query: 589 GLGPRPPPEPGPPDPAGLLSQTAE-VALDLVGDRTPTSEKMDEGQQSSGEDMEISDDEMP 647
G P P EP P P T + A + + PT+ K + + +++ + + P
Sbjct: 756 GTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPK-----KPAPKELAPTTTKGP 810
Query: 648 SAPITSADCPKPMVVTPGAAAVAAPSVLAPTLPLPPPPGFPPLPPPPPPPPPQPGFPMPP 707
TS KP TP A P APT P P P P PPP P P
Sbjct: 811 ----TSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEP 866
Query: 708 PLPPPPPPPPPAHPAVTVPPPP-----LPAPPGVP 737
P + P ++ P P P PGVP
Sbjct: 867 --TTIHKSPDESTPELSAEPTPKALENSPKEPGVP 899
Score = 53.5 bits (127), Expect = 2e-06
Identities = 50/199 (25%), Positives = 66/199 (33%), Gaps = 23/199 (11%)
Query: 561 SSRPSSTGLEDISPTPL--PDSDEDEELDLGLGPRPPPEPGPPDPAGLLSQTAEVALDLV 618
S+ P T + I+P P P+SD +E L + E T E
Sbjct: 247 STSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVE------------TKETTTTNK 294
Query: 619 GDRTPTSEKMDEGQQSSGEDMEISDDEMPSAPITSADCPKPMVVTPGAAAVAAPSVLAPT 678
T EK +++ + + D P++ + + PK T G A + P PT
Sbjct: 295 QTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPA-LTTPKEPTPT 353
Query: 679 LPLPPPPGFPPLPPPPP--PPPPQPGFPMP------PPLPPPPPPPPPAHPAVTVPPPPL 730
P P P P P P P P P P P P P PA T P P
Sbjct: 354 TPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPA 413
Query: 731 PAPPGVPPPPILPPLPPFP 749
P P P P P
Sbjct: 414 PTTTKEPAPTTTKSAPTTP 432
Score = 37.7 bits (86), Expect = 0.11
Identities = 75/395 (18%), Positives = 126/395 (31%), Gaps = 36/395 (9%)
Query: 967 KEPPDTTSSGDQKRLRPSTSVDEEDEESERERDRDMADTPCELAKRDPKGVGVRRRPARP 1026
KEP TT + E + + TP E A PK P P
Sbjct: 566 KEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETA----PTTP 621
Query: 1027 LELDSGGEEDEKESLSEEQESTEEEEEAEEEEEEED----DDDDDSDDRDESENDDEDTA 1082
+L E + E+ T EE A EE ++ + + + N ++ A
Sbjct: 622 KKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPA 681
Query: 1083 LSEASEKDEGDSDEEETVSIVTSKAEATSSSESSESSEFESSSESSPSSSEDEEEVVARE 1142
+ K+ + +E T K A ++ + + + + + ++P +E
Sbjct: 682 --PTTPKEPAPTTPKEPAP-TTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTT 738
Query: 1143 EEEEEEEEEMVAEESMASAGPEDFEQDG-----EEAALAPGAPAVDSLGMEEEVDIETEA 1197
+E + A + P ++ E A P A +L +E +
Sbjct: 739 KEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTL--KEPAPTTPKK 796
Query: 1198 VAPEERPSMLDEPPLPVGVEEPADSREPPEEPGLSQEGAMLLSPEPPAKEVEARP-PLSP 1256
AP+E + P ++PA + P +P+ PA +P P +P
Sbjct: 797 PAPKELAPTTTKGPTSTTSDKPAPTTPKETAP---------TTPKEPAPTTPKKPAPTTP 847
Query: 1257 ERAPEHDLEVEPEPPMMLPLPLQPPLPPPRPPRPPSPPPEPETTDASHPSVPPEPLAEDH 1316
E P EV P + P P P+ P VP
Sbjct: 848 ETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVP----TTKT 903
Query: 1317 PPHTPGLCGSLAKSQSTE----TVPATPGGEPPLS 1347
P T + AK ++TE T P T P ++
Sbjct: 904 PAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMT 938
>gi|150417989 cyclin K isoform 1 [Homo sapiens]
Length = 580
Score = 101 bits (252), Expect = 6e-21
Identities = 104/367 (28%), Positives = 132/367 (35%), Gaps = 79/367 (21%)
Query: 399 PYQTPVAHFPPPPEEPTATAAFGARDSGEFRRAPAPPPLP-PAEPLAKEKPGTPPGPPPP 457
P+ TP PP +PT + P+ P P +P +++P P P P
Sbjct: 266 PHHTPHQLQQPPSLQPTPQVPQVQQSQPSQSSEPSQPQQKDPQQPAQQQQPAQQPKKPSP 325
Query: 458 DTNSMELGGRPTFGWSPEPCDSPGTPTLESSPAGPEKPHDSLDSRIEMLLKEQRTKLLFL 517
+S R +P E+ A P P +I + E L
Sbjct: 326 QPSSPRQVKRAVVV----------SPKEENKAAEPPPP------KIPKI--ETTHPPLPP 367
Query: 518 REPDSDTELQMEGSPISSSSSQLSPLAPFGTNSQPGFRGPTPPSSRPSSTGLEDISPTPL 577
P D + P++++ + P P P + P P P P PL
Sbjct: 368 AHPPPDRK-----PPLAAALGEAEPPGPVDATDLPKVQIPPPAHPAPVH------QPPPL 416
Query: 578 PDSDEDEELDLGLGPRPPPEPGPPDPAGLLSQTAEVALDLVGDRTPTSEKMDEGQQSSGE 637
P RPPP P P+ ++ G T +S EG QS
Sbjct: 417 PH-------------RPPPPP----PSSYMT----------GMSTTSSYMSGEGYQSLQS 449
Query: 638 DMEISDDEMPSAPITSADCPKPMVVTPGAAAVAAPSVLAPTLPLPPPPGFPPLP---PPP 694
M+ E PS P P A P V P PPPP PP P PPP
Sbjct: 450 MMKT---EGPSYGAL------PPAYGPPAHLPYHPHVYPPN---PPPPPVPPPPASFPPP 497
Query: 695 PPPPPQPGFPMPPP-----LPPPPPPPPPAHPAVTVPPPPLPAPPGVPPPPILPP--LPP 747
PPP PG+P PPP PPPPP PP H PPP L PP PPP +PP PP
Sbjct: 498 AIPPPTPGYPPPPPTYNPNFPPPPPRLPPTHAVPPHPPPGLGLPPASYPPPAVPPGGQPP 557
Query: 748 FPPGLFP 754
PP + P
Sbjct: 558 VPPPIPP 564
Score = 75.1 bits (183), Expect = 6e-13
Identities = 90/338 (26%), Positives = 116/338 (34%), Gaps = 104/338 (30%)
Query: 550 SQPGFRGPTPPSSRPSSTGLEDISPTPLPDSDEDEELDLGLGPRPPPEPGPPDPAGLLSQ 609
SQP + P P+ + + P+P P S + + + P+ + P P +
Sbjct: 300 SQPQQKDPQQPAQQ-QQPAQQPKKPSPQPSSPRQVKRAVVVSPKEENKAAEPPPPKI--P 356
Query: 610 TAEVALDLVGDRTPTSEKMDEGQQSSGEDMEISDDEMPSAPITSADCPKPMVVTPG-AAA 668
E + P ++ + GE P P+ + D PK + P A
Sbjct: 357 KIETTHPPLPPAHPPPDRKPPLAAALGE-------AEPPGPVDATDLPKVQIPPPAHPAP 409
Query: 669 VAAPSVLAPTLPLPPP------------------------------PGFPPLPPPPPPPP 698
V P L P PPP P + LPP PP
Sbjct: 410 VHQPPPLPHRPPPPPPSSYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSYGALPPAYGPPA 469
Query: 699 PQPGFP-MPPPLPPPPP-PPPPAHPAVTVPPPPLPAP-PGVPPPP--ILPPLPPFPPGLF 753
P P + PP PPPPP PPPPA + PPP +P P PG PPPP P PP PP L
Sbjct: 470 HLPYHPHVYPPNPPPPPVPPPPA----SFPPPAIPPPTPGYPPPPPTYNPNFPPPPPRLP 525
Query: 754 PVMQVDMSHVLGGQWGGMPMSFQMQTQVLSRLMTGQGACPYPPFMAAAAAAASAGLQFVN 813
P V P+PP GL +
Sbjct: 526 PTHAVP---------------------------------PHPP--------PGLGLPPAS 544
Query: 814 LPPYRGPFSLSNSGPGRGQHWPPLPKFDPSVPPPGYMP 851
PP P PG GQ PP+P P +PPPG P
Sbjct: 545 YPPPAVP-------PG-GQ--PPVP---PPIPPPGMPP 569
Score = 73.2 bits (178), Expect = 2e-12
Identities = 99/382 (25%), Positives = 136/382 (35%), Gaps = 110/382 (28%)
Query: 1201 EERPSMLDEPPLP-VGVEEPADSREP-------PEEPGLSQEGAMLL---SPEPPA-KEV 1248
++ PS+ P +P V +P+ S EP P++P Q+ A SP+P + ++V
Sbjct: 274 QQPPSLQPTPQVPQVQQSQPSQSSEPSQPQQKDPQQPAQQQQPAQQPKKPSPQPSSPRQV 333
Query: 1249 EARPPLSPERAPEHDLEVEPEPPMMLPLPL-QPPLPPPRPP---RPP--------SPPPE 1296
+ +SP+ E + EP PP + + PPLPP PP +PP PP
Sbjct: 334 KRAVVVSPK---EENKAAEPPPPKIPKIETTHPPLPPAHPPPDRKPPLAAALGEAEPPGP 390
Query: 1297 PETTDASHPSVPPEPLAEDHPPHTPGLCGSLAKSQSTETVPATPGGEPPLSGGSSGLSLS 1356
+ TD +PP A P H P +P P PP S +G+S +
Sbjct: 391 VDATDLPKVQIPPP--AHPAPVHQP------------PPLPHRPPPPPP-SSYMTGMSTT 435
Query: 1357 SPQVPGSPFSYPAPSPSLSSGGLPRTPGRDFSFTPTFSEPSGPLLLPVCPLPTGRRDERS 1416
S + G + SL S + +T G + P P P LP P
Sbjct: 436 SSYMSGEGYQ------SLQS--MMKTEGPSYGALPPAYGP--PAHLPYHP---------- 475
Query: 1417 GPLASPVLLETGLPLPLPLPLPLPLALPAVLRAQARAPTPLPPLLPAPLASCPPPMKRKP 1476
P P PP +P P AS PPP P
Sbjct: 476 ---------------------------------HVYPPNPPPPPVPPPPASFPPPAIPPP 502
Query: 1477 GRPRRSPPSMLSLDGPLVRPPAGAALGRELLLLPGQPQTPVFPSTHDPRTVTLDFRNAGI 1536
PP + + P PP P P T P H P + L +
Sbjct: 503 TPGYPPPPPTYNPNFP---PPP-----------PRLPPTHAVPP-HPPPGLGLPPASYPP 547
Query: 1537 PAPPPPLPPQPPPPPPPPPVEP 1558
PA PP P PPP PPP + P
Sbjct: 548 PAVPPGGQPPVPPPIPPPGMPP 569
Score = 72.8 bits (177), Expect = 3e-12
Identities = 73/269 (27%), Positives = 99/269 (36%), Gaps = 61/269 (22%)
Query: 594 PPPEPGPPDPAGLLSQTAEVALDLVGDRTPTSEKMDEGQQSSGEDMEISDDEMPSA-PIT 652
P +P P P SQ ++ + P+ + + QQ + + + PS P +
Sbjct: 277 PSLQPTPQVPQVQQSQPSQSS-------EPSQPQQKDPQQPAQQQQPAQQPKKPSPQPSS 329
Query: 653 SADCPKPMVVTPGAAAVAAPSVLAPTLPLPPPPGFP-------PLPPPPPPPPPQPGFPM 705
+ +VV+P AA PPPP P PLPP PPP +P P+
Sbjct: 330 PRQVKRAVVVSPKEENKAAE---------PPPPKIPKIETTHPPLPPAHPPPDRKP--PL 378
Query: 706 PPPLPPPPPPPPPAH---PAVTVPPPPLPAPPGVPPPPILPPLPPFPPGLFPVMQVDMSH 762
L PP P P V +PPP PAP PPP LP PP PP
Sbjct: 379 AAALGEAEPPGPVDATDLPKVQIPPPAHPAPVHQPPP--LPHRPPPPP------------ 424
Query: 763 VLGGQWGGMPMSFQMQTQVLSRLMTGQGACPYPPFMAAAAAAASAGLQFVNLPPYRGPFS 822
P S+ S M+G+G + + + + G + LPP GP
Sbjct: 425 ---------PSSYMTGMSTTSSYMSGEG------YQSLQSMMKTEGPSYGALPPAYGP-- 467
Query: 823 LSNSGPGRGQHWPPLPKFDPSVPPPGYMP 851
P +PP P P PPP P
Sbjct: 468 -PAHLPYHPHVYPPNPPPPPVPPPPASFP 495
Score = 63.5 bits (153), Expect = 2e-09
Identities = 82/354 (23%), Positives = 121/354 (34%), Gaps = 70/354 (19%)
Query: 1213 PVGVEEPADSREPPEEPGLSQEGAMLLSPEPPAKEVEARPPLSPERAPEHDLEVEPEPPM 1272
P +++P + P+ P + Q S ++ + + P ++ + + P+P
Sbjct: 270 PHQLQQPPSLQPTPQVPQVQQSQPSQSSEPSQPQQKDPQQPAQQQQPAQQPKKPSPQPSS 329
Query: 1273 MLPLPLQPPLPPPRPPRPPS-PPPEPETTDASHPSVPPEPLAEDHPPHTPGLCGSLAKSQ 1331
+ + P + PPP+ + +HP +PP A P P L +L +++
Sbjct: 330 PRQVKRAVVVSPKEENKAAEPPPPKIPKIETTHPPLPP---AHPPPDRKPPLAAALGEAE 386
Query: 1332 STETVPATPGGEPPLSGGSSGLSLSSPQVPGSPFSYPAPSPSLSSGGLPRT----PGRDF 1387
V AT + + + + P P P P P PS G+ T G +
Sbjct: 387 PPGPVDATDLPKVQIPPPAHPAPVHQP--PPLPHRPPPPPPSSYMTGMSTTSSYMSGEGY 444
Query: 1388 SFTPTFSEPSGPLLLPVCPLPTGRRDERSGPLAS-PVLLETGLPLPLPLPLPLPLALPAV 1446
+ + GP G GP A P P P P P+P P PA
Sbjct: 445 QSLQSMMKTEGP--------SYGALPPAYGPPAHLPYHPHVYPPNPPPPPVPPP---PAS 493
Query: 1447 LRAQARAPTPLPPLLPAPLASCPPPMKRKPGRPRRSPPSMLSLDGPLVRPPAGAALGREL 1506
PP +P P PPP PP+ P PP
Sbjct: 494 FP---------PPAIPPPTPGYPPP-----------PPTY----NPNFPPPP-------- 521
Query: 1507 LLLPGQPQTPVFPSTHDPRTVTLDFRNAGIPA---PPPPLPP--QPPPPPPPPP 1555
P P T P P G+P PPP +PP QPP PPP PP
Sbjct: 522 ---PRLPPTHAVPPHPPP--------GLGLPPASYPPPAVPPGGQPPVPPPIPP 564
Score = 62.4 bits (150), Expect = 4e-09
Identities = 69/265 (26%), Positives = 92/265 (34%), Gaps = 48/265 (18%)
Query: 1113 SESSESSEFESSSESSPSSSEDEEEVVAREEEEEEEEEEM---------VAEESMASAGP 1163
++ + ++ PSS + V +EE + E + A P
Sbjct: 311 AQQQQPAQQPKKPSPQPSSPRQVKRAVVVSPKEENKAAEPPPPKIPKIETTHPPLPPAHP 370
Query: 1164 EDFEQDGEEAALAPGAPAVDSLGMEEEVDIETEAVAPEERPSMLDEPPLPVGVEEPADSR 1223
+ AAL P G + D+ + P P+ + +PP P R
Sbjct: 371 PPDRKPPLAAALGEAEPP----GPVDATDLPKVQIPPPAHPAPVHQPP-------PLPHR 419
Query: 1224 EPPEEPG------------LSQEGAMLLSP--EPPAKEVEARPPL--SPERAPEHDLEVE 1267
PP P +S EG L + A PP P P H
Sbjct: 420 PPPPPPSSYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSYGALPPAYGPPAHLPYHPHVYP 479
Query: 1268 PEPPMMLPLPLQPP---LPPPR--PPRPPSPPPEPETTDASHPSVPPE-PLAEDHPPHTP 1321
P PP P P+ PP PPP PP P PPP P T + + P PP P PPH P
Sbjct: 480 PNPP---PPPVPPPPASFPPPAIPPPTPGYPPP-PPTYNPNFPPPPPRLPPTHAVPPHPP 535
Query: 1322 GLCGSLAKSQSTETVPATPGGEPPL 1346
G S VP PGG+PP+
Sbjct: 536 PGLGLPPASYPPPAVP--PGGQPPV 558
Score = 61.2 bits (147), Expect = 9e-09
Identities = 84/342 (24%), Positives = 109/342 (31%), Gaps = 78/342 (22%)
Query: 1317 PPHTPGLCGSLAKSQSTETVPATPGGEPPLSGGSSGLSLSSPQVPGSPFSYPAPSPSLSS 1376
P HTP Q T VP +P S S PQ P PA P S
Sbjct: 266 PHHTPHQLQQPPSLQPTPQVPQVQQSQPSQSSEPSQPQQKDPQQPAQQ-QQPAQQPKKPS 324
Query: 1377 GGLPRTPGRDFSFTPTFSEPSGPLLLPVCPLPTGRRDERSGPLASPVL--LETGLPLPLP 1434
+PS P + + + + + ++ P + +ET P PLP
Sbjct: 325 -----------------PQPSSPRQVKRAVVVSPKEENKAAEPPPPKIPKIETTHP-PLP 366
Query: 1435 LPLPLPLALPAVLRAQARAPTPLP------PLLPAPLASCPPPMKRKPGRPRRSPPSMLS 1488
P P P + A A P P P + P + P P+ + P P R PP
Sbjct: 367 PAHPPPDRKPPLAAALGEAEPPGPVDATDLPKVQIPPPAHPAPVHQPPPLPHRPPPP--- 423
Query: 1489 LDGPLVRPPAGAALGRELLLLPGQPQTPVFPSTHDPRTVTLDFRNAG-----IP---APP 1540
PP+ + G T + S +++ + G +P PP
Sbjct: 424 -------PPSS--------YMTGMSTTSSYMSGEGYQSLQSMMKTEGPSYGALPPAYGPP 468
Query: 1541 PPLPPQP---PPPPPPPPVEPTKLPFKELDNQWPSEAIPPGPRGRDEVTEEYMELAKSRG 1597
LP P PP PPPPPV P F P AIPP G Y
Sbjct: 469 AHLPYHPHVYPPNPPPPPVPPPPASF-------PPPAIPPPTPGYPPPPPTYNPNFPPPP 521
Query: 1598 P---------------WRRPPKKRHEDLVPPAGSPELSPPQP 1624
P PP VPP G P + PP P
Sbjct: 522 PRLPPTHAVPPHPPPGLGLPPASYPPPAVPPGGQPPVPPPIP 563
Score = 51.2 bits (121), Expect = 1e-05
Identities = 91/345 (26%), Positives = 108/345 (31%), Gaps = 75/345 (21%)
Query: 364 SGPPFKAQPQDSATFAHTPPPAQATPAPGFKSAFSPYQTPVAHFPPPPEEPTATAAFGAR 423
S P + Q +D A PAQ P + + SP Q A P EE A
Sbjct: 296 SSEPSQPQQKDPQQPAQQQQPAQQPKKPSPQPS-SPRQVKRAVVVSPKEENKAAE----- 349
Query: 424 DSGEFRRAPAPPPLPPAEPLAKEKPGTPPGPPPPDTNSMELGGRPTFGWSPEPCDSPGTP 483
P PP +P E P PP PPPD L P P D+ P
Sbjct: 350 --------PPPPKIPKIETT---HPPLPPAHPPPDRKP-PLAAALGEAEPPGPVDATDLP 397
Query: 484 TLE-SSPAGPEKPHDSLDSRIEMLLKEQRTKLLFLREPDSDTELQMEGSPISSSSSQLSP 542
++ PA P H + L R P M G +S++SS +S
Sbjct: 398 KVQIPPPAHPAPVH--------------QPPPLPHRPPPPPPSSYMTG--MSTTSSYMSG 441
Query: 543 LAPFGTNSQPGFRGPT----PPSSRPSSTGLEDISPTPLPDSDEDEELDLGLGPRPPPEP 598
S GP+ PP+ P P LP P PPP P
Sbjct: 442 EGYQSLQSMMKTEGPSYGALPPAYGP---------PAHLPYHPHVYP------PNPPPPP 486
Query: 599 GPPDPAGLLSQTAEVALDLVGDRTPTSEKMDEGQQSSGEDMEISDDEMPSAPITSADCPK 658
PP PA PT P P T A P
Sbjct: 487 VPPPPASFPPPAIPPPTPGYPPPPPTYNPN-------------FPPPPPRLPPTHAVPPH 533
Query: 659 PMVVTPGAAAVAAPSVLAPTLPLPPPPGFPPLPPP-PPPPPPQPG 702
P PG P+ P P PP G PP+PPP PPP P G
Sbjct: 534 P---PPGLGL--PPASYPP--PAVPPGGQPPVPPPIPPPGMPPVG 571
Score = 44.7 bits (104), Expect = 9e-04
Identities = 28/87 (32%), Positives = 34/87 (39%), Gaps = 5/87 (5%)
Query: 1241 PEPPAK----EVEARPPLSPERAPEHDLEVEPEPPMMLPLPLQPPLPPPRPPRPPSPPPE 1296
P PPA + P P P ++ P PP + P PP PPP PP+ P
Sbjct: 488 PPPPASFPPPAIPPPTPGYPPPPPTYNPNFPPPPPRLPPTHAVPPHPPPGLGLPPASYPP 547
Query: 1297 PETTDASHPSVPPEPLAEDHPPHTPGL 1323
P P VPP P+ P GL
Sbjct: 548 PAVPPGGQPPVPP-PIPPPGMPPVGGL 573
>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 100 bits (248), Expect = 2e-20
Identities = 116/402 (28%), Positives = 147/402 (36%), Gaps = 66/402 (16%)
Query: 1250 ARPPLSPERAPEHDLEVEPEPPMMLPLPLQPPLP-----PPRPPRPPSPPPEPET---TD 1301
+RPPL P +P P P P P PP P R PPP P+ D
Sbjct: 124 SRPPLLPPGG--RSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPD 181
Query: 1302 ASHPSVPPEPLAEDHPPH---TPGLCGSLAKSQSTETVPATPGGEPPLSGGSSGLSLSSP 1358
+ P VP P PH +P + G + T P PG GG S SP
Sbjct: 182 SIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGS--IRQSP 239
Query: 1359 QVPGSPFSYPAPSPSLSSGGL---PRTPGRDFSFTPTFSEPSGPLLLPVC---PLPTGRR 1412
SPFS P P S L P P P+ + P P P+P+ R
Sbjct: 240 LSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPR 299
Query: 1413 DERSGPLASPVLLETGLPLPLPLPLPLPLA------LPAVLRAQARAPTPLPPLLPAPLA 1466
S P P P P PLP + P + + + PPL P+P
Sbjct: 300 PSASSQAPPPPP-----PPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPL-PSPGR 353
Query: 1467 S--CPPPMKRKPGRPRRSPPSMLSLDGPLVRPPAGAALGRELLLLPGQPQTPVFPSTHDP 1524
S PPP +P P R PP GPL PP + G LP PQ P P
Sbjct: 354 SGPLPPPPSERPPPPVRDPPGR---SGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSP 410
Query: 1525 RTVTLDFRNAGIPAPPPPLPPQPPP---PPPPPPVEPTKLPFKE--LDNQW-------PS 1572
R+ P PPLPP P PPPPPP + F++ +++W P
Sbjct: 411 RS-----------GPRPPLPPDRPSAGAPPPPPPSTSIRNGFQDSPCEDEWESRFYFHPI 459
Query: 1573 EAIPPGPRGRDEVTEEY-MELAKSRGPWRRPPKKRHEDLVPP 1613
+PP P + T+ Y +LA++ R R E PP
Sbjct: 460 SDLPP-PEPYVQTTKSYPSKLARNES---RSGSNRRERGAPP 497
Score = 80.1 bits (196), Expect = 2e-14
Identities = 102/340 (30%), Positives = 123/340 (36%), Gaps = 83/340 (24%)
Query: 1321 PGLCG----SLAKSQSTETVPATPGGEPP--LSGGSSGLSLSSPQVPGSPFSYPAPSPSL 1374
PGL G + K +ST GG P L G S P P +P PSP
Sbjct: 98 PGLGGLFQAGMPKLRSTANRDNDSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGH 157
Query: 1375 SSGGLPRTPGRDFSFTPTFSEPSGPLLLPVCPLPTGRRDERSGPL---ASPVLLETGLPL 1431
SG P P R+ P S P +P P+P+ R +S P + PV P
Sbjct: 158 RSG--PPEPQRNRMPPPRPDVGSKPDSIPP-PVPSTPRPIQSSPHNRGSPPVPGGPRQPS 214
Query: 1432 PLPLPLPLPLALPAVLRAQARAPTPL---------PPLLPAPLASC-------PPPMKRK 1475
P P P P P L + +PL PPL P P + PPP+ +
Sbjct: 215 PGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNR 274
Query: 1476 PGRPRRSPPSMLSLDGPLVRPPAGAALGRELLLLPGQPQTPVFPSTHDPRTVTLDFRNAG 1535
P R + P PP P Q P PST P +A
Sbjct: 275 PSIHREAVP-----------PP------------PPQNNKPPVPSTPRP--------SAS 303
Query: 1536 IPAPPPPLPPQPPPPPPPPPV-----EPTKLPFKELDNQWPSEAIPPGPR-GRDEVTEEY 1589
APPPP PP P PPP PP E +LP + L S + PP P GR
Sbjct: 304 SQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLS---LSSSTPPLPSPGRS------ 354
Query: 1590 MELAKSRGPWRRPPKKRHEDLV--PPAGSPELSPPQPLFR 1627
GP PP +R V PP S L PP P+ R
Sbjct: 355 -------GPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSR 387
Score = 76.3 bits (186), Expect = 3e-13
Identities = 80/278 (28%), Positives = 101/278 (36%), Gaps = 49/278 (17%)
Query: 1201 EERPSMLDEPPLPVGVEEPADSREPPEEPG----LSQEGAMLLSPEPPAKEVEARPPLSP 1256
+ P PP+P G +P+ PP PG G++ SP + RPPL P
Sbjct: 195 QSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPP 254
Query: 1257 ERAPEHDLEVEPEPPMMLPLPLQPPLPPPRPP--RPPSPPPEPETTDASHPSVPPEPLAE 1314
P L+ +P PP PP RP R PPP P+ PS P +
Sbjct: 255 --TPSRALDDKPPPP--------PPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASS 304
Query: 1315 DHPPHTPGLCGSLAKSQSTETVPATPGGEPPLSGGSSGLSLSSPQVPGSPFSYPAPSPSL 1374
PP P P + G PPL SSG + +P++P S + +P L
Sbjct: 305 QAPPPPP---------------PPSRPGPPPLPPSSSG-NDETPRLPQRNLSLSSSTPPL 348
Query: 1375 SSGGLPRTPGRDFSFTPTFSEPSGPLLLPVCPLPTGRRDERSGPLASPVLLETGLPLPLP 1434
S PGR P SE P P RSGPL P +
Sbjct: 349 PS------PGRSGPLPPPPSERPPP--------PVRDPPGRSGPLPPPPPVSRN--GSTS 392
Query: 1435 LPLPLPLALPAVLRAQARAPTPLPPLLP-APLASCPPP 1471
LP LP+ + P PPL P P A PPP
Sbjct: 393 RALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPP 430
Score = 74.3 bits (181), Expect = 1e-12
Identities = 114/451 (25%), Positives = 148/451 (32%), Gaps = 122/451 (27%)
Query: 332 NSPAVTAVAGATAAFRGSSDLPFGAVGGTGGS---SGPP-----FKAQPQDSATFAHT-- 381
+ P G F G G GG GGS GPP F+A + A+
Sbjct: 60 DKPKGAGAGGGGGGFGGGGGFGGGGGGGGGGSFGGGGPPGLGGLFQAGMPKLRSTANRDN 119
Query: 382 ----------PPPAQATPAPGFKSAFSPYQTPV---AHFPPPPEEPTATAAFGARDSGEF 428
PP ++T A F P + PV H PPE
Sbjct: 120 DSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEP--------------- 164
Query: 429 RRAPAPPPLPPAEPLAKEKPGTPPGPPPPDTNSMELGGRPTFGWSPEPCDSP----GTPT 484
+R PPP P KP + P PP P T P P S G+P
Sbjct: 165 QRNRMPPPRPD----VGSKPDSIP-PPVPST--------------PRPIQSSPHNRGSPP 205
Query: 485 LESSPAGPEKPHDSLDSRIEMLLKEQRTKLLFLREPDSDTELQMEGSPISSSSSQLSPLA 544
+ P GP +P P G+ + S + SPL+
Sbjct: 206 V---PGGPRQPSPG---------------------PTPPPFPGNRGTALGGGSIRQSPLS 241
Query: 545 PFGTNSQPGFRGPTPPSSRPSSTGLEDISPTPLPDSDEDEELDLGLGPRPPPEPG-PPDP 603
++S R P PP+ S L+D P P P + P PPP+ PP P
Sbjct: 242 ---SSSPFSNRPPLPPT---PSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVP 295
Query: 604 AGLLSQTAEVALDLVGDRTPTSEKMDEGQQSSGEDMEISDDEMPSAPITSADCPKPMVVT 663
+ TP + +P P +S + P +
Sbjct: 296 S-----------------TPRPSASSQAPPPPPPPSRPGPPPLP--PSSSGNDETPRLPQ 336
Query: 664 PGAAAVAAPSVLAPTLPLPPPPGFPPLPPPP---PPPPPQPGFPMPPPLPPPPPPPPPAH 720
S+ + T PLP P PLPPPP PPPP + PLPPPPP
Sbjct: 337 RNL------SLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGS 390
Query: 721 PAVTVP-PPPLPAPPGVPPPPILPPLPPFPP 750
+ +P P LP+ GV P P PP PP
Sbjct: 391 TSRALPATPQLPSRSGVDSPR-SGPRPPLPP 420
Score = 73.6 bits (179), Expect = 2e-12
Identities = 99/371 (26%), Positives = 124/371 (33%), Gaps = 104/371 (28%)
Query: 424 DSGEFRRAPAPPPLPPAEPLAKEKPGTPP---------------GPPPPDTNSMELGGRP 468
DSG R PP LPP KP +PP GPP P N M RP
Sbjct: 120 DSGGSR----PPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMP-PPRP 174
Query: 469 TFGWSPE--PCDSPGTPT-LESSP---------AGPEKPHDSLDSRIEMLLKEQRTKLLF 516
G P+ P P TP ++SSP GP +P
Sbjct: 175 DVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPG------------------ 216
Query: 517 LREPDSDTELQMEGSPISSSSSQLSPLAPFGTNSQPGFRGPTPPSSRPSSTGLEDISPTP 576
P G+ + S + SPL+ ++S R P PP+ S L+D P P
Sbjct: 217 ---PTPPPFPGNRGTALGGGSIRQSPLS---SSSPFSNRPPLPPTP---SRALDDKPPPP 267
Query: 577 LPDSDEDEELDLGLGPRPPPEPG-PPDPAGLLSQTAEVALDLVGDRTPTSEKMDEGQQSS 635
P + P PPP+ PP P+ TP +
Sbjct: 268 PPPVGNRPSIHREAVPPPPPQNNKPPVPS-----------------TPRPSASSQAPPPP 310
Query: 636 GEDMEISDDEMPSAPITSADCPKPMVVTPGAAAVAAPSVLAPTLPLPPPPGFPPLPPPP- 694
+P P +S + P + S+ + T PLP P PLPPPP
Sbjct: 311 PPPSRPGPPPLP--PSSSGNDETPRLPQRNL------SLSSSTPPLPSPGRSGPLPPPPS 362
Query: 695 --PPPPPQPGFPMPPPLPPPPP--------------PPPPAHPAVTVPP--PPLPAPPGV 736
PPPP + PLPPPPP P P+ V P P P PP
Sbjct: 363 ERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDR 422
Query: 737 PPPPILPPLPP 747
P PP PP
Sbjct: 423 PSAGAPPPPPP 433
Score = 70.1 bits (170), Expect = 2e-11
Identities = 88/343 (25%), Positives = 111/343 (32%), Gaps = 60/343 (17%)
Query: 534 SSSSSQLSPLAPFG---TNSQPGFRGPTPPSSRP-SSTGLEDISPTPLPDSDEDEELDLG 589
+ S PL P G T+++P F P+ P P S G P P + D+G
Sbjct: 119 NDSGGSRPPLLPPGGRSTSAKP-FSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVG 177
Query: 590 LGPR--PPPEPGPPDPAGLLSQTAEVALDLVGDRTPTSEKMDEGQQSSGEDMEISDDEMP 647
P PPP P P P + + G P
Sbjct: 178 SKPDSIPPPVPSTPRP------------------------IQSSPHNRGSPPVPGGPRQP 213
Query: 648 SAPITSADCPKPMVVTPGAAAVAAPSVLAPTLPLPPPPGFPPLPP------PPPPPPP-- 699
S T P G ++ S L+ + P P PP P PPPPPPP
Sbjct: 214 SPGPTPPPFPGNRGTALGGGSIRQ-SPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVG 272
Query: 700 ------QPGFPMPPPLPPPPPPPPPAHPAVTVPPPPLPAPPGVPPPPILPP-------LP 746
+ P PPP PP P P+ + PP P PP P PP LPP P
Sbjct: 273 NRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETP 332
Query: 747 PFPPGLFPVMQVDMSHVLGGQWGGMPMSFQMQTQVLSRLMTGQGACPYPPFMAAAAAAAS 806
P + G+ G +P + R G+ PP + + S
Sbjct: 333 RLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTS 392
Query: 807 AGLQFVNLPPYRGPFSLSNSGPGRGQHWPPLPKFDPS--VPPP 847
L P R SGP PPLP PS PPP
Sbjct: 393 RALPATPQLPSRSGVDSPRSGPR-----PPLPPDRPSAGAPPP 430
Score = 67.0 bits (162), Expect = 2e-10
Identities = 77/256 (30%), Positives = 104/256 (40%), Gaps = 40/256 (15%)
Query: 1193 IETEAVAPEERPSMLDEPPLPVGVEEPADSREPPEEPGLSQEGAMLLSPEPPAKEVEARP 1252
I EAV P P ++PP+P A S+ PP P S+ G P PP+
Sbjct: 277 IHREAVPPP--PPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGP---PPLPPSSSGNDET 331
Query: 1253 PLSPERAPEHDLEVEPEPPMMLPLPLQPPLPPPRPPRPPSPPPEPETTDASHPSVPPEPL 1312
P R P+ +L + P + PLPPP RP PPP + S P PP P+
Sbjct: 332 P----RLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERP--PPPVRDPPGRSGPLPPPPPV 385
Query: 1313 AEDHPPHTPGLCGSLAKS-QSTETVPATPGGEPPLSGGSSGLSLSSPQVPGSPFSYPAPS 1371
+ + GS +++ +T +P+ G + P SG L P G+P P P
Sbjct: 386 SRN---------GSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPSA-GAP---PPPP 432
Query: 1372 PSLS-SGGLPRTPGRD-----FSFTPTFS-EPSGPLLLPVCPLPT--GRRDERSGPLASP 1422
PS S G +P D F F P P P + P+ R + RSG
Sbjct: 433 PSTSIRNGFQDSPCEDEWESRFYFHPISDLPPPEPYVQTTKSYPSKLARNESRSGSNRR- 491
Query: 1423 VLLETGLPLPLPLPLP 1438
E G P PLP P+P
Sbjct: 492 ---ERGAP-PLP-PIP 502
Score = 60.1 bits (144), Expect = 2e-08
Identities = 58/209 (27%), Positives = 75/209 (35%), Gaps = 34/209 (16%)
Query: 1208 DEPPLPVGVEEPADSREPPEEPGLSQEGAMLLSPEPPAKEVEARPPLSPERAPEHDLEVE 1267
+ PPLP D + PP P + ++ PP +PP+ P +
Sbjct: 248 NRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAP 307
Query: 1268 PEPPMMLPLPLQPPLPPPRPPRPPSPPPEPETTDASHPSVPPE--PLAEDHPP-HTPGLC 1324
P PP PP P PP PPS ET P +P L+ PP +PG
Sbjct: 308 PPPP--------PPSRPGPPPLPPSSSGNDET-----PRLPQRNLSLSSSTPPLPSPGRS 354
Query: 1325 GSLAKSQSTETVPAT---PGGEPPL--------SGGSSGLSLSSPQVPG-----SPFSYP 1368
G L S P PG PL +G +S ++PQ+P SP S P
Sbjct: 355 GPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGP 414
Query: 1369 AP--SPSLSSGGLPRTPGRDFSFTPTFSE 1395
P P S G P P S F +
Sbjct: 415 RPPLPPDRPSAGAPPPPPPSTSIRNGFQD 443
Score = 52.0 bits (123), Expect = 6e-06
Identities = 63/247 (25%), Positives = 77/247 (31%), Gaps = 37/247 (14%)
Query: 363 SSGPPFKAQPQDSATFAHTPPPAQATPAPGFKSAFSPYQTPVAHFPPPPEEPTATAAFGA 422
S+ PP P + PPP P P P + PP P P +A+ A
Sbjct: 247 SNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQA 306
Query: 423 RDSGEFRRAPAPPPLPPAEPLAKEKP-----------GTPPGPPPPDTNSMELGGRPTFG 471
P PPPLPP+ E P TPP P P S L P+
Sbjct: 307 PPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSP--GRSGPLPPPPSER 364
Query: 472 WSPEPCDSPGTPTLESSPAGPEKPHDSLDSRIEMLLKEQRTKLLFLREPDSDTELQMEGS 531
P D PG S P P P S L + +L
Sbjct: 365 PPPPVRDPPG----RSGPLPPPPPVSRNGSTSRAL--------------PATPQLPSRSG 406
Query: 532 PISSSSSQLSPLAPFGTNSQPGFRGPTPPSSRPSSTGLEDISPTPLPDSDEDEELDLGLG 591
S S PL P +P P PP PS++ +P D E +
Sbjct: 407 VDSPRSGPRPPLPP----DRPSAGAPPPPP--PSTSIRNGFQDSPCEDEWESRFYFHPIS 460
Query: 592 PRPPPEP 598
PPPEP
Sbjct: 461 DLPPPEP 467
Score = 36.2 bits (82), Expect = 0.32
Identities = 33/121 (27%), Positives = 46/121 (38%), Gaps = 18/121 (14%)
Query: 334 PAVTAVAGATAAFRGSSDLPFGAVGGTGGSSGPPFKAQPQDSATFAHTPPPAQATPAPGF 393
P V+ + A + LP + G SGP P + A PPP + GF
Sbjct: 383 PPVSRNGSTSRALPATPQLPSRS-GVDSPRSGPRPPLPPDRPSAGAPPPPPPSTSIRNGF 441
Query: 394 KSAFSP---------YQTPVAHFPPPPEEPTATAAFGAR------DSGEFRRAPAPPPLP 438
+ SP Y P++ PPP T ++ ++ SG RR PPLP
Sbjct: 442 QD--SPCEDEWESRFYFHPISDLPPPEPYVQTTKSYPSKLARNESRSGSNRRERGAPPLP 499
Query: 439 P 439
P
Sbjct: 500 P 500
>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 100 bits (248), Expect = 2e-20
Identities = 116/402 (28%), Positives = 147/402 (36%), Gaps = 66/402 (16%)
Query: 1250 ARPPLSPERAPEHDLEVEPEPPMMLPLPLQPPLP-----PPRPPRPPSPPPEPET---TD 1301
+RPPL P +P P P P P PP P R PPP P+ D
Sbjct: 124 SRPPLLPPGG--RSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPD 181
Query: 1302 ASHPSVPPEPLAEDHPPH---TPGLCGSLAKSQSTETVPATPGGEPPLSGGSSGLSLSSP 1358
+ P VP P PH +P + G + T P PG GG S SP
Sbjct: 182 SIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGS--IRQSP 239
Query: 1359 QVPGSPFSYPAPSPSLSSGGL---PRTPGRDFSFTPTFSEPSGPLLLPVC---PLPTGRR 1412
SPFS P P S L P P P+ + P P P+P+ R
Sbjct: 240 LSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPR 299
Query: 1413 DERSGPLASPVLLETGLPLPLPLPLPLPLA------LPAVLRAQARAPTPLPPLLPAPLA 1466
S P P P P PLP + P + + + PPL P+P
Sbjct: 300 PSASSQAPPPPP-----PPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPL-PSPGR 353
Query: 1467 S--CPPPMKRKPGRPRRSPPSMLSLDGPLVRPPAGAALGRELLLLPGQPQTPVFPSTHDP 1524
S PPP +P P R PP GPL PP + G LP PQ P P
Sbjct: 354 SGPLPPPPSERPPPPVRDPPGR---SGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSP 410
Query: 1525 RTVTLDFRNAGIPAPPPPLPPQPPP---PPPPPPVEPTKLPFKE--LDNQW-------PS 1572
R+ P PPLPP P PPPPPP + F++ +++W P
Sbjct: 411 RS-----------GPRPPLPPDRPSAGAPPPPPPSTSIRNGFQDSPCEDEWESRFYFHPI 459
Query: 1573 EAIPPGPRGRDEVTEEY-MELAKSRGPWRRPPKKRHEDLVPP 1613
+PP P + T+ Y +LA++ R R E PP
Sbjct: 460 SDLPP-PEPYVQTTKSYPSKLARNES---RSGSNRRERGAPP 497
Score = 80.1 bits (196), Expect = 2e-14
Identities = 102/340 (30%), Positives = 123/340 (36%), Gaps = 83/340 (24%)
Query: 1321 PGLCG----SLAKSQSTETVPATPGGEPP--LSGGSSGLSLSSPQVPGSPFSYPAPSPSL 1374
PGL G + K +ST GG P L G S P P +P PSP
Sbjct: 98 PGLGGLFQAGMPKLRSTANRDNDSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGH 157
Query: 1375 SSGGLPRTPGRDFSFTPTFSEPSGPLLLPVCPLPTGRRDERSGPL---ASPVLLETGLPL 1431
SG P P R+ P S P +P P+P+ R +S P + PV P
Sbjct: 158 RSG--PPEPQRNRMPPPRPDVGSKPDSIPP-PVPSTPRPIQSSPHNRGSPPVPGGPRQPS 214
Query: 1432 PLPLPLPLPLALPAVLRAQARAPTPL---------PPLLPAPLASC-------PPPMKRK 1475
P P P P P L + +PL PPL P P + PPP+ +
Sbjct: 215 PGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNR 274
Query: 1476 PGRPRRSPPSMLSLDGPLVRPPAGAALGRELLLLPGQPQTPVFPSTHDPRTVTLDFRNAG 1535
P R + P PP P Q P PST P +A
Sbjct: 275 PSIHREAVP-----------PP------------PPQNNKPPVPSTPRP--------SAS 303
Query: 1536 IPAPPPPLPPQPPPPPPPPPV-----EPTKLPFKELDNQWPSEAIPPGPR-GRDEVTEEY 1589
APPPP PP P PPP PP E +LP + L S + PP P GR
Sbjct: 304 SQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLS---LSSSTPPLPSPGRS------ 354
Query: 1590 MELAKSRGPWRRPPKKRHEDLV--PPAGSPELSPPQPLFR 1627
GP PP +R V PP S L PP P+ R
Sbjct: 355 -------GPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSR 387
Score = 76.3 bits (186), Expect = 3e-13
Identities = 80/278 (28%), Positives = 101/278 (36%), Gaps = 49/278 (17%)
Query: 1201 EERPSMLDEPPLPVGVEEPADSREPPEEPG----LSQEGAMLLSPEPPAKEVEARPPLSP 1256
+ P PP+P G +P+ PP PG G++ SP + RPPL P
Sbjct: 195 QSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPP 254
Query: 1257 ERAPEHDLEVEPEPPMMLPLPLQPPLPPPRPP--RPPSPPPEPETTDASHPSVPPEPLAE 1314
P L+ +P PP PP RP R PPP P+ PS P +
Sbjct: 255 --TPSRALDDKPPPP--------PPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASS 304
Query: 1315 DHPPHTPGLCGSLAKSQSTETVPATPGGEPPLSGGSSGLSLSSPQVPGSPFSYPAPSPSL 1374
PP P P + G PPL SSG + +P++P S + +P L
Sbjct: 305 QAPPPPP---------------PPSRPGPPPLPPSSSG-NDETPRLPQRNLSLSSSTPPL 348
Query: 1375 SSGGLPRTPGRDFSFTPTFSEPSGPLLLPVCPLPTGRRDERSGPLASPVLLETGLPLPLP 1434
S PGR P SE P P RSGPL P +
Sbjct: 349 PS------PGRSGPLPPPPSERPPP--------PVRDPPGRSGPLPPPPPVSRN--GSTS 392
Query: 1435 LPLPLPLALPAVLRAQARAPTPLPPLLP-APLASCPPP 1471
LP LP+ + P PPL P P A PPP
Sbjct: 393 RALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPP 430
Score = 74.3 bits (181), Expect = 1e-12
Identities = 114/451 (25%), Positives = 148/451 (32%), Gaps = 122/451 (27%)
Query: 332 NSPAVTAVAGATAAFRGSSDLPFGAVGGTGGS---SGPP-----FKAQPQDSATFAHT-- 381
+ P G F G G GG GGS GPP F+A + A+
Sbjct: 60 DKPKGAGAGGGGGGFGGGGGFGGGGGGGGGGSFGGGGPPGLGGLFQAGMPKLRSTANRDN 119
Query: 382 ----------PPPAQATPAPGFKSAFSPYQTPV---AHFPPPPEEPTATAAFGARDSGEF 428
PP ++T A F P + PV H PPE
Sbjct: 120 DSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEP--------------- 164
Query: 429 RRAPAPPPLPPAEPLAKEKPGTPPGPPPPDTNSMELGGRPTFGWSPEPCDSP----GTPT 484
+R PPP P KP + P PP P T P P S G+P
Sbjct: 165 QRNRMPPPRPD----VGSKPDSIP-PPVPST--------------PRPIQSSPHNRGSPP 205
Query: 485 LESSPAGPEKPHDSLDSRIEMLLKEQRTKLLFLREPDSDTELQMEGSPISSSSSQLSPLA 544
+ P GP +P P G+ + S + SPL+
Sbjct: 206 V---PGGPRQPSPG---------------------PTPPPFPGNRGTALGGGSIRQSPLS 241
Query: 545 PFGTNSQPGFRGPTPPSSRPSSTGLEDISPTPLPDSDEDEELDLGLGPRPPPEPG-PPDP 603
++S R P PP+ S L+D P P P + P PPP+ PP P
Sbjct: 242 ---SSSPFSNRPPLPPT---PSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVP 295
Query: 604 AGLLSQTAEVALDLVGDRTPTSEKMDEGQQSSGEDMEISDDEMPSAPITSADCPKPMVVT 663
+ TP + +P P +S + P +
Sbjct: 296 S-----------------TPRPSASSQAPPPPPPPSRPGPPPLP--PSSSGNDETPRLPQ 336
Query: 664 PGAAAVAAPSVLAPTLPLPPPPGFPPLPPPP---PPPPPQPGFPMPPPLPPPPPPPPPAH 720
S+ + T PLP P PLPPPP PPPP + PLPPPPP
Sbjct: 337 RNL------SLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGS 390
Query: 721 PAVTVP-PPPLPAPPGVPPPPILPPLPPFPP 750
+ +P P LP+ GV P P PP PP
Sbjct: 391 TSRALPATPQLPSRSGVDSPR-SGPRPPLPP 420
Score = 73.6 bits (179), Expect = 2e-12
Identities = 99/371 (26%), Positives = 124/371 (33%), Gaps = 104/371 (28%)
Query: 424 DSGEFRRAPAPPPLPPAEPLAKEKPGTPP---------------GPPPPDTNSMELGGRP 468
DSG R PP LPP KP +PP GPP P N M RP
Sbjct: 120 DSGGSR----PPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMP-PPRP 174
Query: 469 TFGWSPE--PCDSPGTPT-LESSP---------AGPEKPHDSLDSRIEMLLKEQRTKLLF 516
G P+ P P TP ++SSP GP +P
Sbjct: 175 DVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPG------------------ 216
Query: 517 LREPDSDTELQMEGSPISSSSSQLSPLAPFGTNSQPGFRGPTPPSSRPSSTGLEDISPTP 576
P G+ + S + SPL+ ++S R P PP+ S L+D P P
Sbjct: 217 ---PTPPPFPGNRGTALGGGSIRQSPLS---SSSPFSNRPPLPPTP---SRALDDKPPPP 267
Query: 577 LPDSDEDEELDLGLGPRPPPEPG-PPDPAGLLSQTAEVALDLVGDRTPTSEKMDEGQQSS 635
P + P PPP+ PP P+ TP +
Sbjct: 268 PPPVGNRPSIHREAVPPPPPQNNKPPVPS-----------------TPRPSASSQAPPPP 310
Query: 636 GEDMEISDDEMPSAPITSADCPKPMVVTPGAAAVAAPSVLAPTLPLPPPPGFPPLPPPP- 694
+P P +S + P + S+ + T PLP P PLPPPP
Sbjct: 311 PPPSRPGPPPLP--PSSSGNDETPRLPQRNL------SLSSSTPPLPSPGRSGPLPPPPS 362
Query: 695 --PPPPPQPGFPMPPPLPPPPP--------------PPPPAHPAVTVPP--PPLPAPPGV 736
PPPP + PLPPPPP P P+ V P P P PP
Sbjct: 363 ERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDR 422
Query: 737 PPPPILPPLPP 747
P PP PP
Sbjct: 423 PSAGAPPPPPP 433
Score = 70.1 bits (170), Expect = 2e-11
Identities = 88/343 (25%), Positives = 111/343 (32%), Gaps = 60/343 (17%)
Query: 534 SSSSSQLSPLAPFG---TNSQPGFRGPTPPSSRP-SSTGLEDISPTPLPDSDEDEELDLG 589
+ S PL P G T+++P F P+ P P S G P P + D+G
Sbjct: 119 NDSGGSRPPLLPPGGRSTSAKP-FSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVG 177
Query: 590 LGPR--PPPEPGPPDPAGLLSQTAEVALDLVGDRTPTSEKMDEGQQSSGEDMEISDDEMP 647
P PPP P P P + + G P
Sbjct: 178 SKPDSIPPPVPSTPRP------------------------IQSSPHNRGSPPVPGGPRQP 213
Query: 648 SAPITSADCPKPMVVTPGAAAVAAPSVLAPTLPLPPPPGFPPLPP------PPPPPPP-- 699
S T P G ++ S L+ + P P PP P PPPPPPP
Sbjct: 214 SPGPTPPPFPGNRGTALGGGSIRQ-SPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVG 272
Query: 700 ------QPGFPMPPPLPPPPPPPPPAHPAVTVPPPPLPAPPGVPPPPILPP-------LP 746
+ P PPP PP P P+ + PP P PP P PP LPP P
Sbjct: 273 NRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETP 332
Query: 747 PFPPGLFPVMQVDMSHVLGGQWGGMPMSFQMQTQVLSRLMTGQGACPYPPFMAAAAAAAS 806
P + G+ G +P + R G+ PP + + S
Sbjct: 333 RLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTS 392
Query: 807 AGLQFVNLPPYRGPFSLSNSGPGRGQHWPPLPKFDPS--VPPP 847
L P R SGP PPLP PS PPP
Sbjct: 393 RALPATPQLPSRSGVDSPRSGPR-----PPLPPDRPSAGAPPP 430
Score = 67.0 bits (162), Expect = 2e-10
Identities = 77/256 (30%), Positives = 104/256 (40%), Gaps = 40/256 (15%)
Query: 1193 IETEAVAPEERPSMLDEPPLPVGVEEPADSREPPEEPGLSQEGAMLLSPEPPAKEVEARP 1252
I EAV P P ++PP+P A S+ PP P S+ G P PP+
Sbjct: 277 IHREAVPPP--PPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGP---PPLPPSSSGNDET 331
Query: 1253 PLSPERAPEHDLEVEPEPPMMLPLPLQPPLPPPRPPRPPSPPPEPETTDASHPSVPPEPL 1312
P R P+ +L + P + PLPPP RP PPP + S P PP P+
Sbjct: 332 P----RLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERP--PPPVRDPPGRSGPLPPPPPV 385
Query: 1313 AEDHPPHTPGLCGSLAKS-QSTETVPATPGGEPPLSGGSSGLSLSSPQVPGSPFSYPAPS 1371
+ + GS +++ +T +P+ G + P SG L P G+P P P
Sbjct: 386 SRN---------GSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPSA-GAP---PPPP 432
Query: 1372 PSLS-SGGLPRTPGRD-----FSFTPTFS-EPSGPLLLPVCPLPT--GRRDERSGPLASP 1422
PS S G +P D F F P P P + P+ R + RSG
Sbjct: 433 PSTSIRNGFQDSPCEDEWESRFYFHPISDLPPPEPYVQTTKSYPSKLARNESRSGSNRR- 491
Query: 1423 VLLETGLPLPLPLPLP 1438
E G P PLP P+P
Sbjct: 492 ---ERGAP-PLP-PIP 502
Score = 60.1 bits (144), Expect = 2e-08
Identities = 58/209 (27%), Positives = 75/209 (35%), Gaps = 34/209 (16%)
Query: 1208 DEPPLPVGVEEPADSREPPEEPGLSQEGAMLLSPEPPAKEVEARPPLSPERAPEHDLEVE 1267
+ PPLP D + PP P + ++ PP +PP+ P +
Sbjct: 248 NRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAP 307
Query: 1268 PEPPMMLPLPLQPPLPPPRPPRPPSPPPEPETTDASHPSVPPE--PLAEDHPP-HTPGLC 1324
P PP PP P PP PPS ET P +P L+ PP +PG
Sbjct: 308 PPPP--------PPSRPGPPPLPPSSSGNDET-----PRLPQRNLSLSSSTPPLPSPGRS 354
Query: 1325 GSLAKSQSTETVPAT---PGGEPPL--------SGGSSGLSLSSPQVPG-----SPFSYP 1368
G L S P PG PL +G +S ++PQ+P SP S P
Sbjct: 355 GPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGP 414
Query: 1369 AP--SPSLSSGGLPRTPGRDFSFTPTFSE 1395
P P S G P P S F +
Sbjct: 415 RPPLPPDRPSAGAPPPPPPSTSIRNGFQD 443
Score = 52.0 bits (123), Expect = 6e-06
Identities = 63/247 (25%), Positives = 77/247 (31%), Gaps = 37/247 (14%)
Query: 363 SSGPPFKAQPQDSATFAHTPPPAQATPAPGFKSAFSPYQTPVAHFPPPPEEPTATAAFGA 422
S+ PP P + PPP P P P + PP P P +A+ A
Sbjct: 247 SNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQA 306
Query: 423 RDSGEFRRAPAPPPLPPAEPLAKEKP-----------GTPPGPPPPDTNSMELGGRPTFG 471
P PPPLPP+ E P TPP P P S L P+
Sbjct: 307 PPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSP--GRSGPLPPPPSER 364
Query: 472 WSPEPCDSPGTPTLESSPAGPEKPHDSLDSRIEMLLKEQRTKLLFLREPDSDTELQMEGS 531
P D PG S P P P S L + +L
Sbjct: 365 PPPPVRDPPG----RSGPLPPPPPVSRNGSTSRAL--------------PATPQLPSRSG 406
Query: 532 PISSSSSQLSPLAPFGTNSQPGFRGPTPPSSRPSSTGLEDISPTPLPDSDEDEELDLGLG 591
S S PL P +P P PP PS++ +P D E +
Sbjct: 407 VDSPRSGPRPPLPP----DRPSAGAPPPPP--PSTSIRNGFQDSPCEDEWESRFYFHPIS 460
Query: 592 PRPPPEP 598
PPPEP
Sbjct: 461 DLPPPEP 467
Score = 36.2 bits (82), Expect = 0.32
Identities = 33/121 (27%), Positives = 46/121 (38%), Gaps = 18/121 (14%)
Query: 334 PAVTAVAGATAAFRGSSDLPFGAVGGTGGSSGPPFKAQPQDSATFAHTPPPAQATPAPGF 393
P V+ + A + LP + G SGP P + A PPP + GF
Sbjct: 383 PPVSRNGSTSRALPATPQLPSRS-GVDSPRSGPRPPLPPDRPSAGAPPPPPPSTSIRNGF 441
Query: 394 KSAFSP---------YQTPVAHFPPPPEEPTATAAFGAR------DSGEFRRAPAPPPLP 438
+ SP Y P++ PPP T ++ ++ SG RR PPLP
Sbjct: 442 QD--SPCEDEWESRFYFHPISDLPPPEPYVQTTKSYPSKLARNESRSGSNRRERGAPPLP 499
Query: 439 P 439
P
Sbjct: 500 P 500
>gi|116256464 hypothetical protein LOC343990 [Homo sapiens]
Length = 962
Score = 99.0 bits (245), Expect = 4e-20
Identities = 160/641 (24%), Positives = 222/641 (34%), Gaps = 83/641 (12%)
Query: 1019 VRRRPARPLELDSGGEEDEKESLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDESENDD 1078
V+ R R ++ + ESLS+ + EEEE E+ E ++ S + + D
Sbjct: 230 VKPRNQRSSKMRRLSSRAQSESLSDLTCTPEEEENEEKPLLEVSPEERPSSGQQDVAPDR 289
Query: 1079 EDTALSEASEKDEGDSDEEETVSIVTSKAEATSSSESSESSEFESSSESSPSSSEDEEEV 1138
A G + + S A S E E SS ++P +E E
Sbjct: 290 GPEPGPPAPLPPPGGA-RARRARLQHSSALTASVEEGGVPGEDPSSRPATPELAEPESAP 348
Query: 1139 VAREEEEEEEEEEMVAEESMASAGPEDFEQDGEEAALAPGAPAVDSLGMEEEVDIETEAV 1198
R E E + GP+ +QDGE P APA D EEV E V
Sbjct: 349 TLRVEPPSPPE-------GPPNPGPDGGKQDGEAPPAGPCAPATDKA---EEVVCAPEDV 398
Query: 1199 APEERPSMLDEPPLPVGVEEPADSREPPEEPGLSQEGAMLLSPEPPAKEVEARPPLSPER 1258
A ++ + P + A S P G + P PP E + P P
Sbjct: 399 ASPFPTAIPEGDTTPPETDPAATSEAPSARDGPERSVPKEAEPTPPVLPDEEKGPPGPAP 458
Query: 1259 APEHDLEVEP------EPPMMLPLPLQPPLPPPRPPRPPSPPPEPETTDASHPSVPPEPL 1312
PE + E EP EP + P P P PP P S + P+ P
Sbjct: 459 EPEREAETEPERGAGTEPERIGTEP--STAPAPSPPAPKSCLKHRPAAASEGPAASPPLA 516
Query: 1313 AEDHPPHTPGLCGSLAKSQSTETVPATPGGEPPLSGGSSGLSLSSPQVPGSPFSYPAPSP 1372
A + PP PG GSL + P E P +G AP
Sbjct: 517 AAESPPVEPG-PGSLDAEAAAPERPKAERAEAPPAGAERA----------------APER 559
Query: 1373 SLSSGGLPRTPGRDFSFTPTFSEPSGPLLLPVCPLPTGRRD-ERSGPL-ASPVLLE--TG 1428
GG + FS + + P + P+ +GR RSGP+ S L+ G
Sbjct: 560 KAERGGAELRGAKKFSVSSCRARPRPGVSRPL-ERASGRLPLARSGPVWRSEAALDDLQG 618
Query: 1429 LPLPL-PLPLPLPLALPAVLRAQARAPTPLPPLL-------------PAPLASCPPPMKR 1474
LP P P P LA + RA +P P P P A P P +
Sbjct: 619 LPEPQHAKPGPRKLAERGPQDSGDRAASPAGPRKSPQEAAAAPGTREPCPAAQEPAPSED 678
Query: 1475 KPGRPRRSPPSMLSL---DGP------LVRPPAGAALGRELLLLPGQPQTPVFPSTHDPR 1525
+ P + + LSL DG + R A L R L +LP + + P+ +
Sbjct: 679 RNPFPVKLRSTSLSLKYRDGASQEVKGVKRYSAEVRLERSLTVLPKEEKCPLGTAPALRG 738
Query: 1526 TVTLDFRNAGIPAPPPPLPPQPPPPPPPPPVEPTKLPFKELDNQWPSEAIPP--GPRGRD 1583
T + G PP PL +PP P P T P + PP GP R+
Sbjct: 739 TRAPSDQGKGKARPPEPLSSKPPLPRKPLLQSFT----------LPHQPAPPDAGPGERE 788
Query: 1584 EVTEEYMELAKSRGPWRRPPKKRHEDLVPPAGSPELSPPQP 1624
E R +RP ++ E +PPA + + QP
Sbjct: 789 PRKE-------PRTAEKRPLRRGAEKSLPPAATGPGADGQP 822
Score = 56.6 bits (135), Expect = 2e-07
Identities = 87/358 (24%), Positives = 114/358 (31%), Gaps = 85/358 (23%)
Query: 561 SSRPSSTGLEDISPTPLPDSDEDEEL------------DLGLGPRPPPEPGPP----DPA 604
SSR S L D++ TP + +E++ L + P PEPGPP P
Sbjct: 244 SSRAQSESLSDLTCTPEEEENEEKPLLEVSPEERPSSGQQDVAPDRGPEPGPPAPLPPPG 303
Query: 605 GLLSQTAEVALDLVGDRTPTSEKMDEGQQSSGEDMEISDDEMPSAPITSADCPKPMVVTP 664
G ++ A + Q SS + + +P +S P
Sbjct: 304 GARARRARL------------------QHSSALTASVEEGGVPGEDPSSR---------P 336
Query: 665 GAAAVAAPSVLAPTLPLPPP--PGFPPLPPP---------PPPPPPQPGF---------- 703
+A P APTL + PP P PP P P PP P P
Sbjct: 337 ATPELAEPES-APTLRVEPPSPPEGPPNPGPDGGKQDGEAPPAGPCAPATDKAEEVVCAP 395
Query: 704 -----PMPPPLPPPPPPPPPAHPAVTVPPPPLPAPP-------GVPPPPILPPLPPFPPG 751
P P +P PP PA T P P P PP+LP PPG
Sbjct: 396 EDVASPFPTAIPEGDTTPPETDPAATSEAPSARDGPERSVPKEAEPTPPVLPDEEKGPPG 455
Query: 752 LFPVMQVDMSHVLGGQWGGMP--MSFQMQTQVLSRLMTGQGACPYPPFMAAAAAAASAGL 809
P + + G P + + T + + P A+ AAS L
Sbjct: 456 PAPEPEREAETEPERGAGTEPERIGTEPSTAPAPSPPAPKSCLKHRPAAASEGPAASPPL 515
Query: 810 QFVNLPPYR-GPFSLSNSGPGRGQHWPPLPKFDPSVPPPGYMPRQEDPHKATVDGVLL 866
PP GP SL P PK + + PP R KA G L
Sbjct: 516 AAAESPPVEPGPGSLDAEAAA-----PERPKAERAEAPPAGAERAAPERKAERGGAEL 568
Score = 51.2 bits (121), Expect = 1e-05
Identities = 124/515 (24%), Positives = 152/515 (29%), Gaps = 143/515 (27%)
Query: 355 GAVGGTGGSSGP--PFKAQPQDSATFAHTPP-PAQATPAPGF------------------ 393
G V G SS P P A+P+ + T PP P + P PG
Sbjct: 325 GGVPGEDPSSRPATPELAEPESAPTLRVEPPSPPEGPPNPGPDGGKQDGEAPPAGPCAPA 384
Query: 394 -----------KSAFSPYQT--PVAHFPPPPEEPTATA-AFGARDSGEF----RRAPAPP 435
+ SP+ T P PP +P AT+ A ARD E P PP
Sbjct: 385 TDKAEEVVCAPEDVASPFPTAIPEGDTTPPETDPAATSEAPSARDGPERSVPKEAEPTPP 444
Query: 436 PLP--------PAEPLAKE------------------KPGTPPGPPPPDTNSMELGGRPT 469
LP PA +E +P T P P PP S L RP
Sbjct: 445 VLPDEEKGPPGPAPEPEREAETEPERGAGTEPERIGTEPSTAPAPSPPAPKSC-LKHRPA 503
Query: 470 FGWSPEPCDSPGTPTLESSPAGPEKPHDSLDSRIEMLLKEQRTKLLFLREPDSDTELQME 529
S P SP ES P P SLD+ +R K P + E
Sbjct: 504 AA-SEGPAASPPLAAAESPPVEPGP--GSLDAEAAA---PERPKAERAEAPPAGAERAAP 557
Query: 530 GSPISSSSSQLSPLAPFGTNSQPGFRGPTPPSSRP------------------SSTGLED 571
++L F +S P P SRP S L+D
Sbjct: 558 ERKAERGGAELRGAKKFSVSSCRA--RPRPGVSRPLERASGRLPLARSGPVWRSEAALDD 615
Query: 572 ISPTPLPD--------------SDEDEELDLGLGPRPPPE-----PGPPDPAGLLSQTAE 612
+ P P D + GPR P+ PG +P + A
Sbjct: 616 LQGLPEPQHAKPGPRKLAERGPQDSGDRAASPAGPRKSPQEAAAAPGTREPCPAAQEPAP 675
Query: 613 VALDLVGDRTPTSEKMDEGQQS----SGEDMEISDDEMPSAPI----TSADCPK----PM 660
DR P K+ S G E+ + SA + + PK P+
Sbjct: 676 SE-----DRNPFPVKLRSTSLSLKYRDGASQEVKGVKRYSAEVRLERSLTVLPKEEKCPL 730
Query: 661 VVTPGAAAVAAPSVLAPTLPLPPPP--GFPPLPPPP-----------PPPPPQPGFPMPP 707
P APS PP P PPLP P PP PG P
Sbjct: 731 GTAPALRGTRAPSDQGKGKARPPEPLSSKPPLPRKPLLQSFTLPHQPAPPDAGPGEREPR 790
Query: 708 PLPPPPPPPPPAHPAVTVPPPPL--PAPPGVPPPP 740
P P A PP P G P PP
Sbjct: 791 KEPRTAEKRPLRRGAEKSLPPAATGPGADGQPAPP 825
Score = 50.8 bits (120), Expect = 1e-05
Identities = 55/211 (26%), Positives = 70/211 (33%), Gaps = 27/211 (12%)
Query: 552 PGFRGPTPPSSRPSSTGLEDISPTPLPDSDEDEELDLGLGPRPPPEPGPPDPAGLLSQTA 611
P R TP + P S + P P+ + D G P GP PA ++
Sbjct: 332 PSSRPATPELAEPESAPTLRVEPPSPPEGPPNPGPDGGKQDGEAPPAGPCAPATDKAEEV 391
Query: 612 EVALDLVGDRTPTSEKMDEGQQSSGEDMEISDDEMPSAPITSADCPKPMVVTPGAAAVAA 671
A + V PT+ + EG + E + E PSA D P+ V
Sbjct: 392 VCAPEDVASPFPTA--IPEGDTTPPETDPAATSEAPSA----RDGPERSV---------- 435
Query: 672 PSVLAPTLPLPP-----PPGFPPLPPPPPPPPPQPGFPMPP------PLPPPPPPPPPAH 720
P PT P+ P PPG P P P+ G P P P P PP
Sbjct: 436 PKEAEPTPPVLPDEEKGPPGPAPEPEREAETEPERGAGTEPERIGTEPSTAPAPSPPAPK 495
Query: 721 PAVTVPPPPLPAPPGVPPPPILPPLPPFPPG 751
+ P P PP PP PG
Sbjct: 496 SCLKHRPAAASEGPAASPPLAAAESPPVEPG 526
Score = 45.1 bits (105), Expect = 7e-04
Identities = 99/420 (23%), Positives = 124/420 (29%), Gaps = 89/420 (21%)
Query: 399 PYQTPVAHFPPP------------PEEPTATAAFGARDSGEFRRAPAPPPL--PPAEPLA 444
P P A PPP TA+ G + PA P L P + P
Sbjct: 291 PEPGPPAPLPPPGGARARRARLQHSSALTASVEEGGVPGEDPSSRPATPELAEPESAPTL 350
Query: 445 KEKPGTPP-GPPPPDTNSMELGGR-PTFGWSPEPCDSPGTPTLESSPAGPEKPHDSLDSR 502
+ +P +PP GPP P + + G P G PC +P T E PE +
Sbjct: 351 RVEPPSPPEGPPNPGPDGGKQDGEAPPAG----PC-APATDKAEEVVCAPEDVASPFPTA 405
Query: 503 IEMLLKEQRTKLLFLREPDSDTELQMEGSPISSSSSQLSPLAPFGTNSQPGFRGPTPPSS 562
I P+ DT E P ++S + + P S P PTPP
Sbjct: 406 I----------------PEGDT-TPPETDPAATSEAPSARDGP--ERSVPKEAEPTPPVL 446
Query: 563 RPSSTGLEDISPTPLPDSDEDEELDLGLGPRP---------PPEPGPPDPAGLLSQTAEV 613
G P P P+ + + E + G G P P P PP P L
Sbjct: 447 PDEEKG--PPGPAPEPEREAETEPERGAGTEPERIGTEPSTAPAPSPPAPKSCLKHRPAA 504
Query: 614 ALD-------LVGDRTPTSEKMDEGQQSSGEDMEISDDEMPSAPITSAD--CPKPMVVTP 664
A + L +P E + E E AP A+ P+
Sbjct: 505 ASEGPAASPPLAAAESPPVEPGPGSLDAEAAAPERPKAERAEAPPAGAERAAPERKAERG 564
Query: 665 GAAAVAAPSVLAPTLPLPPPPGFP----------PLPPPPPP-------------PPPQP 701
GA A + P PG PL P P PQ
Sbjct: 565 GAELRGAKKFSVSSCRARPRPGVSRPLERASGRLPLARSGPVWRSEAALDDLQGLPEPQH 624
Query: 702 GFPMPPPLPPPPPPPPPAHPAVTVPPPPLP----APPGV--PPPPILPPLPPFPPGLFPV 755
P P L P A P P A PG P P P P FPV
Sbjct: 625 AKPGPRKLAERGPQDSGDRAASPAGPRKSPQEAAAAPGTREPCPAAQEPAPSEDRNPFPV 684
Score = 37.0 bits (84), Expect = 0.19
Identities = 54/235 (22%), Positives = 81/235 (34%), Gaps = 31/235 (13%)
Query: 273 TPLTPRLGTPFSQDSSYSSRQPTPSYLFSQDPA---------VTFKARRHESKFTDAYNR 323
+P PR +P ++ +R+P P+ +Q+PA V ++ K+ D ++
Sbjct: 646 SPAGPRK-SPQEAAAAPGTREPCPA---AQEPAPSEDRNPFPVKLRSTSLSLKYRDGASQ 701
Query: 324 RHEHHYVHNSPAVTAVAGATAAFRGSSDLPFGAVGGTGGSSGPPFKAQPQDSATFAHTPP 383
E V A + + P G G+ P + + + A P
Sbjct: 702 --EVKGVKRYSAEVRLERSLTVLPKEEKCPLGTAPALRGTRAPSDQGKGK-----ARPPE 754
Query: 384 PAQATPAPGFKSAFSPYQTPVAHFPPPPEEPTATAAFGARDSGEFRRAPAPPPL----PP 439
P + P K + P H P PP+ A G R+ + R PL
Sbjct: 755 PLSSKPPLPRKPLLQSFTLP--HQPAPPD-----AGPGEREPRKEPRTAEKRPLRRGAEK 807
Query: 440 AEPLAKEKPGTPPGPPPPDTNSMELGGRPTFGWSPEPCDSPGTPTLESSPAGPEK 494
+ P A PG P PP R T P D PG TL+S P K
Sbjct: 808 SLPPAATGPGADGQPAPPWITVTRQKRRGTLDQPPNQEDKPGARTLKSEPGKQAK 862
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.133 0.405
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 115,406,591
Number of Sequences: 37866
Number of extensions: 9339779
Number of successful extensions: 327190
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 2446
Number of HSP's successfully gapped in prelim test: 2640
Number of HSP's that attempted gapping in prelim test: 55193
Number of HSP's gapped (non-prelim): 104877
length of query: 1923
length of database: 18,247,518
effective HSP length: 117
effective length of query: 1806
effective length of database: 13,817,196
effective search space: 24953855976
effective search space used: 24953855976
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.