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Search of human proteins with 209977046
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|209977046 fibrous sheath CABYR binding protein [Homo
sapiens]
(825 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens] 1594 0.0
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] 134 4e-31
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 127 3e-29
gi|110349719 titin isoform N2-A [Homo sapiens] 124 4e-28
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 124 5e-28
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 124 5e-28
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 120 5e-27
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 120 5e-27
gi|149773456 hypothetical protein LOC643314 [Homo sapiens] 107 5e-23
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 100 6e-21
gi|163965366 nascent polypeptide-associated complex alpha subuni... 98 4e-20
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 97 8e-20
gi|153945728 microtubule-associated protein 1B [Homo sapiens] 94 4e-19
gi|150170670 piccolo isoform 2 [Homo sapiens] 86 1e-16
gi|150378539 piccolo isoform 1 [Homo sapiens] 86 1e-16
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 84 5e-16
gi|20143482 melanoma antigen family E, 1 [Homo sapiens] 84 7e-16
gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo sap... 82 2e-15
gi|15559211 RE1-silencing transcription factor [Homo sapiens] 81 3e-15
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ... 81 3e-15
gi|116325993 c114 SLIT-like testicular protein [Homo sapiens] 81 3e-15
gi|110665701 leucine rich repeat containing 37A [Homo sapiens] 81 3e-15
gi|47132519 Ras association and pleckstrin homology domains 1 is... 80 6e-15
gi|91982772 mucin 17 [Homo sapiens] 80 6e-15
gi|239740955 PREDICTED: similar to c114 SLIT-like testicular pro... 80 8e-15
gi|239740953 PREDICTED: similar to c114 SLIT-like testicular pro... 80 8e-15
gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo sap... 80 8e-15
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 80 1e-14
gi|239745855 PREDICTED: hypothetical protein XP_002343606 [Homo ... 80 1e-14
gi|242117953 SH3 domain-containing protein C1orf113 isoform 1 [H... 79 1e-14
>gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens]
Length = 825
Score = 1594 bits (4128), Expect = 0.0
Identities = 825/825 (100%), Positives = 825/825 (100%)
Query: 1 MVGKSQQTDVIEKKKHMAIPKSSSPKATHRIGNTSGSKGSYSAKAYESIRVSSELQQTWT 60
MVGKSQQTDVIEKKKHMAIPKSSSPKATHRIGNTSGSKGSYSAKAYESIRVSSELQQTWT
Sbjct: 1 MVGKSQQTDVIEKKKHMAIPKSSSPKATHRIGNTSGSKGSYSAKAYESIRVSSELQQTWT 60
Query: 61 KRKHGQEMTSKSLQTDTIVEEKKEVKLVEETVVPEEKSADVREAAIELPESVQDVEIPPN 120
KRKHGQEMTSKSLQTDTIVEEKKEVKLVEETVVPEEKSADVREAAIELPESVQDVEIPPN
Sbjct: 61 KRKHGQEMTSKSLQTDTIVEEKKEVKLVEETVVPEEKSADVREAAIELPESVQDVEIPPN 120
Query: 121 IPSVQLKMDRSQQTSRTGYWTMMNIPPVEKVDKEQQTYFSESEIVVISRPDSSSTKSKED 180
IPSVQLKMDRSQQTSRTGYWTMMNIPPVEKVDKEQQTYFSESEIVVISRPDSSSTKSKED
Sbjct: 121 IPSVQLKMDRSQQTSRTGYWTMMNIPPVEKVDKEQQTYFSESEIVVISRPDSSSTKSKED 180
Query: 181 ALKHKSSGKIFASEHPEFQPATNSNEEIGQKNISRTSFTQETKKGPPVLLEDELREEVTV 240
ALKHKSSGKIFASEHPEFQPATNSNEEIGQKNISRTSFTQETKKGPPVLLEDELREEVTV
Sbjct: 181 ALKHKSSGKIFASEHPEFQPATNSNEEIGQKNISRTSFTQETKKGPPVLLEDELREEVTV 240
Query: 241 PVVQEGSAVKKVASAEIEPPSTEKFPAKIQPPLVEEATAKAEPRPAEETHVQVQPSTEET 300
PVVQEGSAVKKVASAEIEPPSTEKFPAKIQPPLVEEATAKAEPRPAEETHVQVQPSTEET
Sbjct: 241 PVVQEGSAVKKVASAEIEPPSTEKFPAKIQPPLVEEATAKAEPRPAEETHVQVQPSTEET 300
Query: 301 PDAEAATAVAENSVKVQPPPAEEAPLVEFPAEIQPPSAEESPSVELLAEILPPSAEESPS 360
PDAEAATAVAENSVKVQPPPAEEAPLVEFPAEIQPPSAEESPSVELLAEILPPSAEESPS
Sbjct: 301 PDAEAATAVAENSVKVQPPPAEEAPLVEFPAEIQPPSAEESPSVELLAEILPPSAEESPS 360
Query: 361 EEPPAEILPPPAEKSPSVELLGEIRSPSAQKAPIEVQPLPAEGALEEAPAKVEPPTVEET 420
EEPPAEILPPPAEKSPSVELLGEIRSPSAQKAPIEVQPLPAEGALEEAPAKVEPPTVEET
Sbjct: 361 EEPPAEILPPPAEKSPSVELLGEIRSPSAQKAPIEVQPLPAEGALEEAPAKVEPPTVEET 420
Query: 421 LADVQPLLPEEAPREEARELQLSTAMETPAEEAPTEFQSPLPKETTAEEASAEIQLLAAT 480
LADVQPLLPEEAPREEARELQLSTAMETPAEEAPTEFQSPLPKETTAEEASAEIQLLAAT
Sbjct: 421 LADVQPLLPEEAPREEARELQLSTAMETPAEEAPTEFQSPLPKETTAEEASAEIQLLAAT 480
Query: 481 EPPADETPAEARSPLSEETSAEEAHAEVQSPLAEETTAEEASAEIQLLAAIEAPADETPA 540
EPPADETPAEARSPLSEETSAEEAHAEVQSPLAEETTAEEASAEIQLLAAIEAPADETPA
Sbjct: 481 EPPADETPAEARSPLSEETSAEEAHAEVQSPLAEETTAEEASAEIQLLAAIEAPADETPA 540
Query: 541 EAQSPLSEETSAEEAPAEVQSPSAKGVSIEEAPLELQPPSGEETTAEEASAAIQLLAATE 600
EAQSPLSEETSAEEAPAEVQSPSAKGVSIEEAPLELQPPSGEETTAEEASAAIQLLAATE
Sbjct: 541 EAQSPLSEETSAEEAPAEVQSPSAKGVSIEEAPLELQPPSGEETTAEEASAAIQLLAATE 600
Query: 601 ASAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQP 660
ASAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQP
Sbjct: 601 ASAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQP 660
Query: 661 PPAEEAPAEVQPPPAEEAPAEVQSLPAEETPIEETLAAVHSPPADDVPAEEASVDKHSPP 720
PPAEEAPAEVQPPPAEEAPAEVQSLPAEETPIEETLAAVHSPPADDVPAEEASVDKHSPP
Sbjct: 661 PPAEEAPAEVQPPPAEEAPAEVQSLPAEETPIEETLAAVHSPPADDVPAEEASVDKHSPP 720
Query: 721 ADLLLTEEFPIGEASAEVSPPPSEQTPEDEALVENVSTEFQSPQVAGIPAVKLGSVVLEG 780
ADLLLTEEFPIGEASAEVSPPPSEQTPEDEALVENVSTEFQSPQVAGIPAVKLGSVVLEG
Sbjct: 721 ADLLLTEEFPIGEASAEVSPPPSEQTPEDEALVENVSTEFQSPQVAGIPAVKLGSVVLEG 780
Query: 781 EAKFEEVSKINSVLKDLSNTNDGQAPTLEIESVFHIELKQRPPEL 825
EAKFEEVSKINSVLKDLSNTNDGQAPTLEIESVFHIELKQRPPEL
Sbjct: 781 EAKFEEVSKINSVLKDLSNTNDGQAPTLEIESVFHIELKQRPPEL 825
>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
Length = 2400
Score = 134 bits (336), Expect = 4e-31
Identities = 185/662 (27%), Positives = 262/662 (39%), Gaps = 106/662 (16%)
Query: 171 DSSSTKSKEDALKHKSSGKIFASEHPEFQPATNSNEEIGQKNISRTSFTQETKKGPPVL- 229
D +++ DA+ + GK SE T++ E+G+ ++ + G
Sbjct: 1757 DPKLGEAEGDAMAQEREGKTHNSE-------TSAGSELGEAEQEGEGISERGETGGQGSG 1809
Query: 230 LEDELREEVTV-----PVVQEGSAVKKVASAEIEP-PSTEKFPAKIQPPLVEEATAKAEP 283
ED L+ E P +G+ + AE E P +E A +EA +A+P
Sbjct: 1810 HEDNLQGEAAAGGDQDPGQSDGAEGIEAPEAEGEAQPESEGVEAPEAEGDAQEAEGEAQP 1869
Query: 284 RP----AEETHVQVQPSTE--ETPDAE------AATAVAENSVKVQPPPAEEAPLVEFPA 331
A E + QP +E ETP+AE + A A + K P E +E
Sbjct: 1870 ESEDVEAPEAEGEAQPESEDVETPEAEWEVQPESEGAEAPEAEKEAQPETESVEALETEG 1929
Query: 332 EIQPPS--AEESPSVELLAEI---LPPSAEESPSEEPPAEILPPPAE-KSPSVELLGEIR 385
E +P S AE + E E P +E S+E E P + ++ VE+ +
Sbjct: 1930 EDEPESEGAEAQEAEEAAQEAEGQTQPESEVIESQEAEEEAQPESEDVEALEVEVETQEA 1989
Query: 386 SPSAQKAPIEVQPLPAEGALEEAPAKVEPPTVEETLADVQPLLPEEAPREEARELQLSTA 445
AQ +V+ AEG ++EA + +P E + QP ++ EEA+E++ T
Sbjct: 1990 EGEAQPESEDVEAPEAEGEMQEAEEEAQP---ESDGVEAQP----KSEGEEAQEVEGET- 2041
Query: 446 METPAEEAPTEFQSPLPK-ETTAEEASAEIQLLAATEPPADETPAEARSPLSEETSAEEA 504
+T + P P+ E A+EA E+Q E EA P SE+ A+EA
Sbjct: 2042 QKTEGDAQPESDGVEAPEAEEEAQEAEGEVQ----------EAEGEAH-PESEDVDAQEA 2090
Query: 505 HAEVQSPLAEETTAEEASAEIQLLAAIEAPADETPAEAQSPLSEETSAEEAPAEVQSPSA 564
E Q P +E A EA E Q IEAP ET EAQ P SE A EA E Q P +
Sbjct: 2091 EGEAQ-PESEGVEAPEAEGEAQKAEGIEAP--ETEGEAQ-PESEGIEAPEAEGEAQ-PES 2145
Query: 565 KGVSIEEAPLELQPPSG---EETTAEEASAAIQLLAATEASAEEAPAE--VQPPPAE-EA 618
+GV ++A E QP S + EEA ++ + A EA E P ++ P AE EA
Sbjct: 2146 EGVEAQDAEGEAQPESEGIEAQEAEEEAQPELEGVEAPEAEGEAQPESEGIEAPEAEGEA 2205
Query: 619 PAEVQPPPAEEAPAEVQPPP----AEEAPAEVQPPPAEEAPAEVQPPP--------AEEA 666
E++ A EA E QP P EA E QP E E + P +EEA
Sbjct: 2206 QPELEGVEAPEAEEEAQPEPEGVETPEAEGEAQPESEGETQGEKKGSPQVSLGDGQSEEA 2265
Query: 667 PAEVQPPPAEEAPAEVQSLPAEETPIEE---------------------------TLAAV 699
P P E+ P S P +TP + L
Sbjct: 2266 SESSSPVP-EDRPTPPPS-PGGDTPHQRPGSQTGPSSSRASSWGNCWQKDSENDHVLGDT 2323
Query: 700 HSPPADDV--PAEEASVDKHSPPADLLLTEEFPIGEASAEVSPPPSEQTPEDEALVENVS 757
SP A P E + P + EE P+G + E ED+AL
Sbjct: 2324 RSPDAKSTGTPHAERKATRMYPESSTSEQEEAPLGSRTPEQGASEGYDLQEDQALGSLAP 2383
Query: 758 TE 759
TE
Sbjct: 2384 TE 2385
Score = 76.6 bits (187), Expect = 9e-14
Identities = 103/366 (28%), Positives = 144/366 (39%), Gaps = 43/366 (11%)
Query: 464 ETTAEEASAEIQLLAATEPPADETPAEARSPLSEETSAEEAHAEVQSPLAEETTAEEASA 523
ET + + E L D+ P ++ +E A EA E Q P +E A EA
Sbjct: 1802 ETGGQGSGHEDNLQGEAAAGGDQDPGQSDG--AEGIEAPEAEGEAQ-PESEGVEAPEA-- 1856
Query: 524 EIQLLAAIEAPADETPAEAQSPLSEETSAEEAPAEVQSPSAKGVSIEEAPLELQPPS--G 581
E A E EAQ P SE+ A EA E Q P ++ V EA E+QP S
Sbjct: 1857 --------EGDAQEAEGEAQ-PESEDVEAPEAEGEAQ-PESEDVETPEAEWEVQPESEGA 1906
Query: 582 EETTAE-EASAAIQLLAATEASAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPP--- 637
E AE EA + + A E E+ P +E A A+ A+EA + QP
Sbjct: 1907 EAPEAEKEAQPETESVEALETEGED------EPESEGAEAQEAEEAAQEAEGQTQPESEV 1960
Query: 638 -PAEEAPAEVQP--PPAEEAPAEVQPPPAE-EAPAEVQPPPAEEAPAEVQSLPAEETPIE 693
++EA E QP E EV+ AE EA E + A EA E+Q E P
Sbjct: 1961 IESQEAEEEAQPESEDVEALEVEVETQEAEGEAQPESEDVEAPEAEGEMQEAEEEAQPES 2020
Query: 694 ETLAAVHSPPADDVPAEEASVDK----HSPPADLLLTEEF--PIGEASAEVSPPPSEQTP 747
+ + A ++ E K P +D + E EA EV E P
Sbjct: 2021 DGVEAQPKSEGEEAQEVEGETQKTEGDAQPESDGVEAPEAEEEAQEAEGEVQEAEGEAHP 2080
Query: 748 EDEALVENVSTEFQSPQVAGIPAVKLGSVVLEGEAKFEEVSKINSVLKDLSNTNDG-QAP 806
E E + + P+ G+ A + EGEA+ E + + ++G +AP
Sbjct: 2081 ESEDVDAQEAEGEAQPESEGVEAPE-----AEGEAQKAEGIEAPETEGEAQPESEGIEAP 2135
Query: 807 TLEIES 812
E E+
Sbjct: 2136 EAEGEA 2141
Score = 56.6 bits (135), Expect = 9e-08
Identities = 105/487 (21%), Positives = 168/487 (34%), Gaps = 81/487 (16%)
Query: 53 SELQQTWTKRKHGQEMTSKSLQTDTIVEEKKEVKLVEETVVPEEKSADVREAAIELPESV 112
+E Q+ + + T + E ++E + E V E + +EA E
Sbjct: 1938 AEAQEAEEAAQEAEGQTQPESEVIESQEAEEEAQPESEDVEALEVEVETQEAEGEAQPES 1997
Query: 113 QDVEIPPNIPSVQLKMDRSQQTSRTGYWTMMNIPPVEKVDKEQQTYFSESEIVVISRPDS 172
+DVE P +Q + +Q P + V+ + ++ E++ V
Sbjct: 1998 EDVEAPEAEGEMQEAEEEAQ-------------PESDGVEAQPKSEGEEAQEV------E 2038
Query: 173 SSTKSKEDALKHKSSGKIFASEHPEFQPATNSNEEIGQKNISRTSFTQETKKGPPVLLED 232
T+ E + +S G E Q A +E E
Sbjct: 2039 GETQKTEGDAQPESDGVEAPEAEEEAQEAEGEVQE----------------------AEG 2076
Query: 233 ELREEVTVPVVQEGSAVKKVASAEIEPPSTEKFPAKIQPPLVEEATAKAEPRPAEETHVQ 292
E E QE A E +P S ++ P E KAE A ET +
Sbjct: 2077 EAHPESEDVDAQE-------AEGEAQPES-----EGVEAPEAEGEAQKAEGIEAPETEGE 2124
Query: 293 VQPSTE--ETPDAEAATAVAENSVKVQPPPAEEAPLVEFPAEIQPPSAEESPSVELLAEI 350
QP +E E P+AE V+ Q E P E I+ AEE EL
Sbjct: 2125 AQPESEGIEAPEAEGEAQPESEGVEAQDAEGEAQPESE---GIEAQEAEEEAQPELEGVE 2181
Query: 351 LPPSAEESPSEEPPAEILPPPAEKSPSVELLGEIRSPSAQKAPIEVQPLPAEGALEEAPA 410
P + E+ E E P AE EL G + +P A++ E QP P EA
Sbjct: 2182 APEAEGEAQPESEGIE--APEAEGEAQPELEG-VEAPEAEE---EAQPEPEGVETPEAEG 2235
Query: 411 KVEPPTVEETLADVQPLLPEEAPREEARELQLSTAMETPA---EEAPTEFQSP---LPKE 464
+ +P + ET + + +P+ + Q A E+ + E+ PT SP P +
Sbjct: 2236 EAQPESEGETQGE-----KKGSPQVSLGDGQSEEASESSSPVPEDRPTPPPSPGGDTPHQ 2290
Query: 465 TTAEEASAEIQLLAA------TEPPADETPAEARSPLSEETSAEEAHAEVQSPLAEETTA 518
+ ++ + D + RSP ++ T A + E +T+
Sbjct: 2291 RPGSQTGPSSSRASSWGNCWQKDSENDHVLGDTRSPDAKSTGTPHAERKATRMYPESSTS 2350
Query: 519 EEASAEI 525
E+ A +
Sbjct: 2351 EQEEAPL 2357
Score = 46.2 bits (108), Expect = 1e-04
Identities = 81/319 (25%), Positives = 117/319 (36%), Gaps = 34/319 (10%)
Query: 447 ETPAEEAPTEFQSPLPKETTAEEASAEIQLLAATEPPADETPAEARSPLSEETSAEEAHA 506
E AE E ++ E AE E L T+ + + + EET EE
Sbjct: 1273 EDEAERDSEEQRASSNLEQLAENTVQEEVQLEETKEGTEGEGLQEEAVQLEETKTEEGLQ 1332
Query: 507 E--VQSPLAEETTAEEASAEIQLLAAIEAPADETPAEAQSPLSEETSAEEAPAEVQSPSA 564
E VQ +ET E E L IE ET E L EE E E
Sbjct: 1333 EEGVQLEETKETEGEGQQEEEAQLEEIE----ETGGEG---LQEEGVQLEEVKEGPEGGL 1385
Query: 565 KGVSIEEAPLELQPPSGEETTAEEASAAIQLLAATEASAEEAPAEVQPPPAEEAPAEVQP 624
+G ++EE EE EE S Q L+ EAS+ + + P +E A
Sbjct: 1386 QGEALEEG-------LKEEGLPEEGSVHGQELS--EASSPDGKGSQEDDPVQEEEAGRAS 1436
Query: 625 PPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQS 684
AE PAE P E PP+ + + P A E + Q P E P
Sbjct: 1437 ASAEPCPAEGTEEPTE--------PPSHLSETD---PSASERQSGSQLEPGLEKPPGATM 1485
Query: 685 LPAEETPIEETLAAVHSPPADDVPAEEASVDKHSPPADLLL--TEEFPIGEASAEVSPPP 742
+ E T + T A + A A++D +LL TE+ + ++ V+
Sbjct: 1486 MGQEHTQAQPTQGAAERSSS---VACSAALDCDPIWVSVLLKKTEKAFLAHLASAVAELR 1542
Query: 743 SEQTPEDEALVENVSTEFQ 761
+ +D L++ ++ E Q
Sbjct: 1543 ARWGLQDNDLLDQMAAELQ 1561
Score = 37.7 bits (86), Expect = 0.044
Identities = 55/272 (20%), Positives = 96/272 (35%), Gaps = 36/272 (13%)
Query: 201 ATNSNEEIGQKNISRTSFTQETKKGPPVLLEDELREEVTVPVVQEGSAVKKVASAEIEPP 260
ATN +E R S Q L E+ ++EEV + +EG+ + + ++
Sbjct: 1270 ATNEDEA------ERDSEEQRASSNLEQLAENTVQEEVQLEETKEGTEGEGLQEEAVQLE 1323
Query: 261 STEKFPAKIQPPLVEEATAKAEPRPAEETHVQVQPSTEETPDAEAATAVAENSVKVQPPP 320
T+ + + E T + E +E Q++ E + V VK P
Sbjct: 1324 ETKTEEGLQEEGVQLEETKETEGEGQQEEEAQLEEIEETGGEGLQEEGVQLEEVKEGPEG 1383
Query: 321 AEEAPLVEFPAEIQPPSAEESPSVELLAEILPPSAEESPSEEPPAEILPPPAEKSPSVEL 380
+ +E + + E S + L+E P + S ++P
Sbjct: 1384 GLQGEALEEGLKEEGLPEEGSVHGQELSEASSPDGKGSQEDDP----------------- 1426
Query: 381 LGEIRSPSAQKAPIEVQPLPAEGALEEAPAKVEPPTVEETLADVQPLLPEEAPREEAREL 440
++ A +A +P PAEG E EPP+ L++ P E R+ +L
Sbjct: 1427 ---VQEEEAGRASASAEPCPAEGTEE----PTEPPS---HLSETDPSASE---RQSGSQL 1473
Query: 441 QLSTAMETPAEEAPTEFQSPLPKETTAEEASA 472
+ A E P + AE +S+
Sbjct: 1474 EPGLEKPPGATMMGQEHTQAQPTQGAAERSSS 1505
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 127 bits (320), Expect = 3e-29
Identities = 157/606 (25%), Positives = 260/606 (42%), Gaps = 79/606 (13%)
Query: 160 SESEIVVISRPDSSSTKSKEDALKHKSSGKIFASEHPEFQPATNSNEEIGQKNISRTSFT 219
SE +I V+ + + + +E + + + ++ E E + EE G++ +
Sbjct: 440 SEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGG-- 497
Query: 220 QETKKGPPVLLEDELREEVTVPVVQEGSAVKKVASAEIEP---PSTEKFPAKIQPPLVEE 276
+E K PP +E PV +E + + S E E P+ K P K + P EE
Sbjct: 498 EEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEE 557
Query: 277 ATAKAEPRPAEETHVQV-----QPSTEETPDAEAATAVAE--NSVKVQPPPAEEAPLVEF 329
A + E + E+ + P ++P E A + AE + K + P EEA +
Sbjct: 558 AKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEA---KS 614
Query: 330 PAEIQPPSAEESPSVELLAEILPPSAEESPSEEP---PAEILPPPAEKSPSVE-----LL 381
PAE + P EE+ S AE+ P +SP++E P + P E++ S E +
Sbjct: 615 PAEAKSPVKEEAKSP---AEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVK 671
Query: 382 GEIRSPSAQKAPIEVQ---PLPAEGALEE---APAKVEPPTVEETLADVQPLLP--EEAP 433
E +SP K+P++ + P A+ ++E +P K + P EE + + P EEA
Sbjct: 672 AEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAK 731
Query: 434 REEARELQLSTAMETPA-----EEAPT-EFQSPLPKETTAEEASAEIQLLA--ATEPPAD 485
E + + ++P E+A T + +SP K EEA + A P +
Sbjct: 732 TPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKE 791
Query: 486 E--TPAEARSPLSEETSAEEAH----AEVQSPLAEETTAEEASAEIQLLAAIEAPADETP 539
E +P +A+SPL E+ A E EV+SP+ EE +E + E P
Sbjct: 792 EVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVK------------EPP 839
Query: 540 AEAQSPLSEETSAEEAPAEVQSPSAKGVSIEEAPLELQP-PSGEETTAEEASAAIQLLAA 598
+A+ E+APA ++ K EEAP + P P EE +E + +
Sbjct: 840 KKAEE--------EKAPATPKTEEKKDSKKEEAPKKEAPKPKVEE--KKEPAVEKPKESK 889
Query: 599 TEASAEEAPAEVQ-PPPAEEAPAEVQ----PPPAEEAPAEVQPPPAEEAPAEVQPPPAEE 653
EA EEA + + P P +EAPA+V+ P E+ + P +A +P +E
Sbjct: 890 VEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKE 949
Query: 654 APAEVQPPPAEEAPAEVQPPPAE-EAPAEVQSLPAE--ETPIEETLAAVHSPPADDVPAE 710
A E + E+A + P E +A + ++L E + E+ + + D P E
Sbjct: 950 AAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKDSKPPE 1009
Query: 711 EASVDK 716
+A+ DK
Sbjct: 1010 KATEDK 1015
Score = 111 bits (278), Expect = 2e-24
Identities = 155/585 (26%), Positives = 242/585 (41%), Gaps = 111/585 (18%)
Query: 243 VQEGSAVKKVASAEIEPPSTEKFPAKIQPPLVEEATAKAEPRPAEETHVQVQPSTEETPD 302
V+ +K V +E E E+ + Q + EE T + E EE + EE +
Sbjct: 438 VKSEEKIKVVEKSEKETVIVEEQTEETQ--VTEEVTEEEEKEAKEE-----EGKEEEGGE 490
Query: 303 AEAATAVAENSVKVQPPPAEEAPLVEFPAEIQPPSAEESPSVELLAEILPPSAEESPSEE 362
E A E + + PPAEEA E E + P EE+ S AE P EE+ S
Sbjct: 491 EEEAEGGEEET---KSPPAEEAASPE--KEAKSPVKEEAKSP---AEAKSPEKEEAKS-- 540
Query: 363 PPAEILPPPAEKSPSVELLGEIRSPSAQKAPI-EVQPLPAEGALEEAPAKVEPPTVEETL 421
PAE+ P KSP+ E E +SP K+P E PAE ++P K + P EE
Sbjct: 541 -PAEVKSPEKAKSPAKE---EAKSPPEAKSPEKEEAKSPAE---VKSPEKAKSPAKEEAK 593
Query: 422 ADVQPLLPEEAP---REEARELQLSTAMETPAEEAPTEFQSPLPKETTAEEASAEIQLLA 478
+ + PE+A +EEA+ +P E +SP+ +E
Sbjct: 594 SPAEAKSPEKAKSPVKEEAK--------------SPAEAKSPVKEE-------------- 625
Query: 479 ATEPPADETPAEARSPLSEETSAEEAHAEVQSPLAEETTAEEASAEIQLLAAIEAPADET 538
A P ++P +A+SP EE + E + +SP EE + E + + ++A A ++
Sbjct: 626 AKSPAEVKSPEKAKSPTKEEAKSPE---KAKSPEKEEAKSPEKAK-----SPVKAEA-KS 676
Query: 539 PAEAQSPLSEETSAEEAPAEVQSPSAKGVSIEEAPLELQPPSGEETTAEEASAAIQLLAA 598
P +A+SP+ E + E AK EEA P + EEA + + +
Sbjct: 677 PEKAKSPVKAEAKSPE--------KAKSPVKEEAK---SPEKAKSPVKEEAKSPEKAKSP 725
Query: 599 TEASAEEAPAEVQPPPAEEAPA-EVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAE 657
+ A + P + + P EEA + E P + +V+ P A+ E PA++ P +
Sbjct: 726 VKEEA-KTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEK 784
Query: 658 VQPPPAEE--APAEVQPPPAEEAPAEVQSLPAEETPIEETLAAVHSPPADDVPAEEASVD 715
+ P EE +P + + P E+A A + +P +E V SP ++ +E V
Sbjct: 785 AKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKE--------EVKSPVKEEEKPQEVKVK 836
Query: 716 KHSPPADLLLTEEFPIGEASAEVSPPPSEQTPEDEALVENVSTEFQSPQVAGIPAVKLGS 775
+ A+ E+ P + E E+ P+ EA V E + P V K+
Sbjct: 837 EPPKKAE---EEKAPATPKTEEKKDSKKEEAPKKEAPKPKVE-EKKEPAVEKPKESKV-- 890
Query: 776 VVLEGEAKFEEVSKINSVLKDLSNTNDGQAPTLEIESVFHIELKQ 820
EAK EE V PT E E+ +E+K+
Sbjct: 891 -----EAKKEEAEDKKKV------------PTPEKEAPAKVEVKE 918
Score = 90.1 bits (222), Expect = 7e-18
Identities = 104/379 (27%), Positives = 166/379 (43%), Gaps = 50/379 (13%)
Query: 428 LPEEAPREEARELQLSTAMETPAEEAPTEFQSPLPKETTAEEASAEIQLLAATEPPADET 487
LPE P+ + +ST ++ +EE + + EE + E Q+ TE +E
Sbjct: 422 LPEGLPKIPS----VSTHIKVKSEEKIKVVEKSEKETVIVEEQTEETQV---TEEVTEEE 474
Query: 488 PAEARSPLSEETSAEEAHAEVQSPLAEETTAEEASAEIQLLAAIEAPADETPAEAQSPLS 547
EA+ EE EE EE AE E + A EA + E EA+SP+
Sbjct: 475 EKEAKE---EEGKEEEG--------GEEEEAEGGEEETKSPPAEEAASPEK--EAKSPVK 521
Query: 548 EETSAEEAPAEVQSPSAKGVSIEEAPLELQPPSGEETTAEEASAAIQLLAATEASAEEAP 607
EE ++PAE +SP + ++P E++ P ++ A+E + + + E ++P
Sbjct: 522 EEA---KSPAEAKSPEKEEA---KSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSP 575
Query: 608 AEVQPPPAEEAPA--EVQPPPAEEAPAEVQPPPAEEA--PAEVQPPPAEEA--PAEVQPP 661
AEV+ P ++PA E + P ++P + + P EEA PAE + P EEA PAEV+ P
Sbjct: 576 AEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSP 635
Query: 662 PAEEAPAEVQPPPAEEAPA-EVQSLPAEETPIEETLAAVHSP--PADDVPAEEASVDKHS 718
++P + + E+A + E + + E A SP V AE S +K
Sbjct: 636 EKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAK 695
Query: 719 PPADLLLTEEFPIGEASAEVSPPPSEQTPEDEALVENVSTEFQSPQVAGIPAVKLGSVVL 778
P + EE ++ + P E+ E V E ++P+ A P +
Sbjct: 696 SP----VKEE---AKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSP--------V 740
Query: 779 EGEAKFEEVSKINSVLKDL 797
+ EAK E +K K L
Sbjct: 741 KEEAKSPEKAKSPEKAKTL 759
Score = 34.3 bits (77), Expect = 0.48
Identities = 45/249 (18%), Positives = 93/249 (37%), Gaps = 27/249 (10%)
Query: 67 EMTSKSLQTDTIVEEKKEVKLVEETVVPEEKSADVREAAIELPESVQDVEIPPNIPSVQL 126
E L+ D EK E+ EE P ++ +E ++ P + E P P +
Sbjct: 797 EKAKSPLKEDAKAPEK-EIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEE 855
Query: 127 KMDRSQQTSRTGYWTMMNIPPVEKVDKEQQTYFSESEIVVISRPDSSSTKSKEDALKHKS 186
K D ++ + P KV+++++ + +P S ++K++ + K
Sbjct: 856 KKDSKKEEAPK------KEAPKPKVEEKKEP--------AVEKPKESKVEAKKEEAEDKK 901
Query: 187 SGKIFASEHPEFQPATNSNEEIGQKNISRTSFTQETKKGPPVLLEDELREEVTVPVVQEG 246
E P + E+ +++ T+ KK P +D +E + P ++
Sbjct: 902 KVPTPEKEAP-------AKVEV-KEDAKPKEKTEVAKKEP----DDAKAKEPSKPAEKKE 949
Query: 247 SAVKKVASAEIEPPSTEKFPAKIQPPLVEEATAKAEPRPAEETHVQVQPSTEETPDAEAA 306
+A +K + E + E+ P ++ T EP + + ST++
Sbjct: 950 AAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKDSKPPE 1009
Query: 307 TAVAENSVK 315
A + + K
Sbjct: 1010 KATEDKAAK 1018
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 124 bits (311), Expect = 4e-28
Identities = 189/761 (24%), Positives = 279/761 (36%), Gaps = 117/761 (15%)
Query: 66 QEMTSKSLQTDTIVEEKKEVKLVEETVVPEEKSADVREAAIELPESV-QDVEIPPNIPSV 124
+E + + + I EE ++ VEE V P +++A E P V + VE PP S
Sbjct: 10239 EEPEEEPISEEEIPEEPPSIEEVEE-VAPPRVPEVIKKAVPEAPTPVPKKVEAPPAKVSK 10297
Query: 125 QLKMDRSQQTSRTGYWTMMNIPPVEKVDKEQQTYFSESEIVVISRPDSSSTKSKEDALKH 184
++ ++ + +P V K E++ + E V P + E+ +
Sbjct: 10298 KIPEEKVPVPVQKKEAPPAKVPEVPKKVPEKKVLVPKKEAV----PPAKGRTVLEEKVSV 10353
Query: 185 KSSGKIFASEHPEFQPATNSNEEIGQKN--------ISRTSF--TQETKKGPPVLLEDEL 234
++ E E + EEI ++ F +E K +E+E
Sbjct: 10354 AFRQEVVVKERLELEVVEAEVEEIPEEEEFHEVEEYFEEGEFHEVEEFIKLEQHRVEEEH 10413
Query: 235 REEVTVPVVQEGSAVK-KVASAEIEPPSTEKFPAKIQPPLVEEATAKAEPR---PAEETH 290
R E V++ A + +V PP + KI PP ++ K PR PA+
Sbjct: 10414 RVEKVHRVIEVFEAEEVEVFEKPKAPPKGPEISEKIIPP--KKPPTKVVPRKEPPAKVPE 10471
Query: 291 VQVQPSTEETPDAEAATAVAENSVKVQPPPAEEAPLVEFPAEIQPPSAEESPSVELLAEI 350
V + EE V V PP E P + P + P E+P
Sbjct: 10472 VPKKIVVEEKVRVPEEPRVPPTKVPEVLPPKEVVPEKKVP--VPPAKKPEAP-------- 10521
Query: 351 LPPSAEESPSEEPPAEILPPPAEKSPSVELLGEIRSPSA----QKAPIEVQPLPAEGALE 406
PP E+P E P + +P P K P V P A +K P + P P E
Sbjct: 10522 -PPKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKAAVPEKKVPEAIPPKPESPPPE 10580
Query: 407 --EAPAKVEP----PTVEETLADVQPLLPEEAPREEARELQLSTAMETPAEEAPTEFQSP 460
EAP +V P P +V P+ EAP+E E ++ E PT+
Sbjct: 10581 VPEAPKEVVPEKKVPAAPPKKPEVTPVKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPE- 10639
Query: 461 LPKETTAEEASAEIQLLAATEPPADETPAEARSPLSEETSAEEAHAEVQSPLAEETTAEE 520
+PK E+ E PP E+P EE + EE AEV EE E
Sbjct: 10640 VPKVAVPEKKVPE------AIPPKPESPPPEVFEEPEEVALEEPPAEV----VEEP---E 10686
Query: 521 ASAEIQLLAAIEAPADETPAEA---QSPLSEETSAEEAPAEV-----------QSPSAKG 566
+A Q+ + P E A A + P E P EV + P A
Sbjct: 10687 PAAPPQVTVPPKKPVPEKKAPAVVAKKPELPPVKVPEVPKEVVPEKKVPLVVPKKPEAPP 10746
Query: 567 VSIEEAPLELQP------PSGEETTAEEASAAIQLLAATEASAEEAPAEVQPPPAE--EA 618
+ E P E+ P P E + + E A P + PP E E
Sbjct: 10747 AKVPEVPKEVVPEKKVAVPKKPEVPPAKVPEVPKKPVLEEKPAVPVPERAESPPPEVYEE 10806
Query: 619 PAEVQPPPAEEAPAEVQPPP-AEEAPAEVQPPPAEEAPAEV-------------QPPPAE 664
P E+ P E AP E +P P AEE EV PP E P ++ PPP E
Sbjct: 10807 PEEIAPEE-EIAPEEEKPVPVAEEEEPEVPPPAVPEEPKKIIPEKKVPVIKKPEAPPPKE 10865
Query: 665 EAPAEV--------QPPPAEEAPAEVQSLPAEETPIEETLAAVHSPPADDVPAEEASVDK 716
P +V +PPP AP P E+ ++E + + + P VP +K
Sbjct: 10866 PEPEKVIEKPKLKPRPPPPPPAP------PKED--VKEKIFQLKAIPKKKVP------EK 10911
Query: 717 HSPPADLLLTE-EFPIGEASAEVSPPPSEQTPEDEALVENV 756
P + LT + P GE P + P++E ++++V
Sbjct: 10912 PQVPEKVELTPLKVPGGEKKVRKLLPERKPEPKEEVVLKSV 10952
Score = 114 bits (284), Expect = 5e-25
Identities = 185/781 (23%), Positives = 297/781 (38%), Gaps = 136/781 (17%)
Query: 77 TIVEEKKEVKLVEETVVPEEKSADVREAAIE-LPESVQDVEIPPNIPS---------VQL 126
T++EEK V +E VV E +V EA +E +PE + E+ ++L
Sbjct: 10345 TVLEEKVSVAFRQEVVVKERLELEVVEAEVEEIPEEEEFHEVEEYFEEGEFHEVEEFIKL 10404
Query: 127 KMDRSQQTSRTGYWTMMNIPPVEKVDKEQQTYFSESEIVVISRPDSSSTKSKEDALKHKS 186
+ R ++ R VEKV + + + +E E+ V +P + K E + K
Sbjct: 10405 EQHRVEEEHR-----------VEKVHRVIEVFEAE-EVEVFEKP-KAPPKGPEISEKIIP 10451
Query: 187 SGKIFASEHPEFQPATNSNEEIGQKNISRTSFTQETKKGPPVLLEDELREEVTVPVVQEG 246
K P +P E + + E + PP + + L + VP ++
Sbjct: 10452 PKKPPTKVVPRKEPPAKVPEVPKKIVVEEKVRVPEEPRVPPTKVPEVLPPKEVVP--EKK 10509
Query: 247 SAVKKVASAEIEPPSTEKFPAKIQPPLVEEATAKAEPRPAEETHVQVQPSTEETPDAEAA 306
V E PP + P ++ P E+ P+ E +V E P A
Sbjct: 10510 VPVPPAKKPEAPPPKVPEAPKEVVP---EKKVPVPPPKKPEVPPTKVP----EVPKA--- 10559
Query: 307 TAVAENSVKVQPPPAEEAPLVEFPAEIQPPSAEESPSVELLA------EILPPSAEESPS 360
AV E V PP E+P P E+ E P ++ A E+ P E+P
Sbjct: 10560 -AVPEKKVPEAIPPKPESP----PPEVPEAPKEVVPEKKVPAAPPKKPEVTPVKVPEAPK 10614
Query: 361 EEPPAEILPPPAEKSPSV---------------ELLGEIRSPSAQKAPIEVQPLPAEGAL 405
E P + +P P K P V + + E P + P EV P E AL
Sbjct: 10615 EVVPEKKVPVPPPKKPEVPPTKVPEVPKVAVPEKKVPEAIPPKPESPPPEVFEEPEEVAL 10674
Query: 406 EEAPAKV-------EPPTVEETLADVQPLLPEEAPREEARELQLSTAM--ETPAE----- 451
EE PA+V PP V T+ +P+ ++AP A++ +L E P E
Sbjct: 10675 EEPPAEVVEEPEPAAPPQV--TVPPKKPVPEKKAPAVVAKKPELPPVKVPEVPKEVVPEK 10732
Query: 452 ----------EAPTEFQSPLPKETTAEEASAEIQLLAATEPPADETPAEARSPLSEETSA 501
EAP +PKE E+ ++ + E P + P + P+ EE A
Sbjct: 10733 KVPLVVPKKPEAPPAKVPEVPKEVVPEK---KVAVPKKPEVPPAKVPEVPKKPVLEEKPA 10789
Query: 502 EEAHAEVQSPLAEE-TTAEEASAEIQLLAAIEAPADETPAEAQSPLSEETSAEEAPAEVQ 560
+SP E EE + E ++ AP +E P P++EE E P V
Sbjct: 10790 VPVPERAESPPPEVYEEPEEIAPEEEI-----APEEEKPV----PVAEEEEPEVPPPAVP 10840
Query: 561 SPSAKGVSIEEAPLELQP--PSGEETTAEEASAAIQLL--------AATEASAEEAPAEV 610
K + ++ P+ +P P +E E+ +L A + +E ++
Sbjct: 10841 EEPKKIIPEKKVPVIKKPEAPPPKEPEPEKVIEKPKLKPRPPPPPPAPPKEDVKEKIFQL 10900
Query: 611 QPPPAEEAPAEVQ-PPPAEEAPAEV--------------QPPPAEEAPAE--VQPPPAEE 653
+ P ++ P + Q P E P +V +P P EE + ++ P EE
Sbjct: 10901 KAIPKKKVPEKPQVPEKVELTPLKVPGGEKKVRKLLPERKPEPKEEVVLKSVLRKRPEEE 10960
Query: 654 APAEVQPPPAEEA--PAEVQPPPAEE-APAEVQSLPAEETPIEETLAAVHSPPADDVPAE 710
P +V+P E+ PA +PPP + EV ++ E I E PA +PA
Sbjct: 10961 EP-KVEPKKLEKVKKPAVPEPPPPKPVEEVEVPTVTKRERKIPEPTKVPEIKPAIPLPAP 11019
Query: 711 EASVDKHSPPADLLLTEEFPIGEASAEVSPPPSEQTPEDEALVENVSTEFQSPQ--VAGI 768
E K P A++ + P+ ++ P + +A + E P+ + G+
Sbjct: 11020 E---PKPKPEAEVKTIKPPPVEPEPTPIAAPVTVPVVGKKAEAKAPKEEAAKPKGPIKGV 11076
Query: 769 P 769
P
Sbjct: 11077 P 11077
Score = 113 bits (283), Expect = 6e-25
Identities = 162/607 (26%), Positives = 228/607 (37%), Gaps = 83/607 (13%)
Query: 228 VLLEDEL-REEVTVPVVQEGSAVKKVASAEIEP--PSTEKFPAKIQ--PPLVEEATAKAE 282
VL E+E+ EE +P +E ++ E E P E+ P + + PP E + E
Sbjct: 10107 VLFEEEIVPEEEVLPEEEEVLPEEEEVLPEEEEVLPEEEEIPPEEEEVPPEEEYVPEEEE 10166
Query: 283 PRPAEETHVQVQPSTE-ETPDAEAATAVAENSVKVQPPPAEEAPLVEFPAEIQPPSAEES 341
P EE +V+P P E V E V + P EEAP + P E+ E+
Sbjct: 10167 FVPEEEVLPEVKPKVPVPAPVPEIKKKVTEKKVVI--PKKEEAPPAKVP-EVPKKVEEKR 10223
Query: 342 PSVELLAEILPPSAEESPSEEPPAEILPPPAEKSPSVELLGEI---RSPSAQKAPIEVQP 398
+ E+LP E P EEP +E P E+ PS+E + E+ R P K + P
Sbjct: 10224 IILPKEEEVLPVEVTEEPEEEPISEEEIP--EEPPSIEEVEEVAPPRVPEVIKKAVPEAP 10281
Query: 399 LPAEGALEEAPAKVEPPTVEETLADVQPLLPEEAPREEARELQLSTAME---TPAEEA-- 453
P +E PAKV EE + P+ +EAP + E+ + P +EA
Sbjct: 10282 TPVPKKVEAPPAKVSKKIPEEKVP--VPVQKKEAPPAKVPEVPKKVPEKKVLVPKKEAVP 10339
Query: 454 PTEFQSPLPKETTA----EEASAEIQLLAATEPPADETPAEARSPLSEETSAEEAHAEV- 508
P + ++ L ++ + E E L E +E P E EE E EV
Sbjct: 10340 PAKGRTVLEEKVSVAFRQEVVVKERLELEVVEAEVEEIPEEEEFHEVEEYFEEGEFHEVE 10399
Query: 509 ------QSPLAEETTAEEASAEIQLLAAIEAPADETPAEA-------------QSPLSEE 549
Q + EE E+ I++ A E E P + P ++
Sbjct: 10400 EFIKLEQHRVEEEHRVEKVHRVIEVFEAEEVEVFEKPKAPPKGPEISEKIIPPKKPPTKV 10459
Query: 550 TSAEEAPAEVQSPSAKGVSIEEAPLELQPPSGEETTAEEASAAIQLLAATEASAEEAPAE 609
+E PA+V K + +EE + P T E +++ + A
Sbjct: 10460 VPRKEPPAKVPEVPKK-IVVEEKVRVPEEPRVPPTKVPEVLPPKEVVPEKKVPVPPAKKP 10518
Query: 610 VQPPP-AEEAPAEVQPPPAEEAPA----EVQPPPAEEAPAEVQP--------PPAEEAPA 656
PPP EAP EV P P EV P E P P PP E+P
Sbjct: 10519 EAPPPKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKAAVPEKKVPEAIPPKPESP- 10577
Query: 657 EVQPPPAEEAPAEVQP-------PPA--EEAPAEVQSLPAEETPIEETLAAVHSPPADDV 707
PP EAP EV P PP E P +V P E P E V P +V
Sbjct: 10578 ---PPEVPEAPKEVVPEKKVPAAPPKKPEVTPVKVPEAPKEVVP--EKKVPVPPPKKPEV 10632
Query: 708 PAEEASVDKHSPPADLLLTEEFPIGEA---SAEVSPPPSEQTPEDEALVENVSTEFQSPQ 764
P + P + E + EA E PP + PE+ AL E + + P+
Sbjct: 10633 PPTKV------PEVPKVAVPEKKVPEAIPPKPESPPPEVFEEPEEVALEEPPAEVVEEPE 10686
Query: 765 VAGIPAV 771
A P V
Sbjct: 10687 PAAPPQV 10693
Score = 110 bits (275), Expect = 5e-24
Identities = 167/697 (23%), Positives = 255/697 (36%), Gaps = 120/697 (17%)
Query: 82 KKEVKLVEETVVPEEKSADVREAAIELPESV--QDVEIPPNIPSVQLKMDRSQQTSRTGY 139
++E L EE +VPEE+ E + E V ++ E+ P + + +
Sbjct: 10103 QEEEVLFEEEIVPEEEVLPEEEEVLPEEEEVLPEEEEVLPEEEEIPPEEEE--------- 10153
Query: 140 WTMMNIPPVEKVDKEQQTYFSESEIVVISRPDSSSTKSKEDALKHKSSGKIFASEHPEFQ 199
+PP E+ E++ + E E++ +P + K + K+ + E
Sbjct: 10154 -----VPPEEEYVPEEEEFVPEEEVLPEVKPKVPVPAPVPEIKKKVTEKKVVIPKKEEAP 10208
Query: 200 PATNSNEEIGQKNISRTSFTQETKKGPPVLLEDELREEVTVPVVQEGSAVKKVASAEIEP 259
PA K P V + E + + +P +E V+ E EP
Sbjct: 10209 PA----------------------KVPEVPKKVE-EKRIILPKEEEVLPVEVTEEPEEEP 10245
Query: 260 PSTEKFPAKIQPPLVEEATAKAEPRPAEETHVQVQPSTEETPDAEAATAVAENSVKVQPP 319
S E+ P +PP +EE A PR E V EA T V + KV+ P
Sbjct: 10246 ISEEEIPE--EPPSIEEVEEVAPPRVPEVIKKAVP---------EAPTPVPK---KVEAP 10291
Query: 320 PAEEAPLVEFPAEIQPPSAEESPSVELLAEILPPSAEESPSEEPPAEILPPPAEKSPSVE 379
PA+ + + P +E+P P E P + P ++L P E P +
Sbjct: 10292 PAKVSKKIPEEKVPVPVQKKEAP---------PAKVPEVPKKVPEKKVLVPKKEAVPPAK 10342
Query: 380 ---LLGE-----IRSPSAQKAPIEVQPLPAEGALEEAPAKVEPPTVEETLAD-----VQP 426
+L E R K +E++ + AE +EE P + E VEE + V+
Sbjct: 10343 GRTVLEEKVSVAFRQEVVVKERLELEVVEAE--VEEIPEEEEFHEVEEYFEEGEFHEVEE 10400
Query: 427 LLPEEAPR--EEARELQLSTAMETPAEEAPTEFQSPL--PKETTAEEASAEIQLLAATEP 482
+ E R EE R ++ +E E F+ P PK E +++ +P
Sbjct: 10401 FIKLEQHRVEEEHRVEKVHRVIEVFEAEEVEVFEKPKAPPKGPEISE-----KIIPPKKP 10455
Query: 483 PADETPAE---ARSP-LSEETSAEEAHAEVQSPLAEETTAEEASAEIQLLAAIEAPADET 538
P P + A+ P + ++ EE + P T E P E
Sbjct: 10456 PTKVVPRKEPPAKVPEVPKKIVVEEKVRVPEEPRVPPTKVPEV-----------LPPKEV 10504
Query: 539 PAEAQSPLSEETSAEEAPAEVQSPSAKGVSIEEAPLELQPPSGEETTAEEASAAIQLLAA 598
E + P+ E P +V P A + E + + PP E + +
Sbjct: 10505 VPEKKVPVPPAKKPEAPPPKV--PEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKA--- 10559
Query: 599 TEASAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEV 658
A E+ E PP E P EV P E P E + P A EV P EAP EV
Sbjct: 10560 --AVPEKKVPEAIPPKPESPPPEVPEAPKEVVP-EKKVPAAPPKKPEVTPVKVPEAPKEV 10616
Query: 659 QPPPAEEAPAEVQPPPAEEAP----AEVQSLPAEETPIEETLAAVHSPPADDVPAEEASV 714
P E V PP E P EV + E + E + P +V E V
Sbjct: 10617 VP----EKKVPVPPPKKPEVPPTKVPEVPKVAVPEKKVPEAIPPKPESPPPEVFEEPEEV 10672
Query: 715 DKHSPPADLLLTEEFPIGEASAEVSPPPSEQTPEDEA 751
PPA+++ E P A +V+ PP + PE +A
Sbjct: 10673 ALEEPPAEVV---EEPEPAAPPQVTVPPKKPVPEKKA 10706
Score = 105 bits (261), Expect = 2e-22
Identities = 190/767 (24%), Positives = 293/767 (38%), Gaps = 103/767 (13%)
Query: 41 YSAKAYESIRVSSELQQTWTKRKHGQEMTSKSLQTDTIVEEKKEVKLVEETVVPEEKSAD 100
Y K +E + E Q + E + + T E+ VK V E VP + A
Sbjct: 9751 YDYKEFEEYEPTEEYDQYEEYEEREYERYEEHEEYITEPEKPIPVKPVPEEPVPTKPKAP 9810
Query: 101 VREAAIELPESVQDVEIPPNIPSVQLKMDRSQQTSRTGYWTMMNIPPVEKVDKEQQTYFS 160
+ L ++V + ++P IP +LK PP KV +E + F
Sbjct: 9811 PAKV---LKKAVPEEKVPVPIPK-KLK------------------PPPPKVPEEPKKVFE 9848
Query: 161 ESEIVVISRPDSSSTKSKEDALKHKSSGKIFASEHPEFQPATNSNEEIGQKNISRTSFTQ 220
E + I++ + E A K K +E P + + + +
Sbjct: 9849 EKIRISITKREKEQVT--EPAAKVPMKPKRVVAEEKVPVPRKEVAPPVRVPEVPKELEPE 9906
Query: 221 ETKKGPPVLLEDELREEVTVPVVQEGSAVKKVASAEIEPPSTEKFPAKIQPPLVEEATAK 280
E V E+E+ V +V+E ++ E E TE+ + P V E K
Sbjct: 9907 E------VAFEEEVVTHVEEYLVEE----EEEYIHEEEEFITEEEVVPVIPVKVPEVPRK 9956
Query: 281 AEPRPAEETHVQVQPSTEETPDAEAATAVA--ENSVKVQPPPAEEAPLVEFPAEIQPPSA 338
P P E+ V V P +E P A+ E V V P E+ P + P + P
Sbjct: 9957 --PVPEEKKPVPV-PKKKEAPPAKVPEVPKKPEEKVPVLIPKKEKPPPAKVPEVPKKPVP 10013
Query: 339 EESPSVELLAEILPPSAE--ESPSEEPPAEILPPPAEKSPSVELLGEIRSPSAQKAPIEV 396
EE V + ++ P A+ E P + P + +P PA K ++ +P A+ +
Sbjct: 10014 EEKVPVPVPKKVEAPPAKVPEVPKKPVPEKKVPVPAPK--------KVEAPPAKVPEVPK 10065
Query: 397 QPLPAEGALEEAPAKVE--PPTVEETLADVQPLLPEEAPREEARELQLSTAMETPAEEAP 454
+ +P E P KVE PP V + V +P P+EE L P EE
Sbjct: 10066 KLIPEEKKPTPVPKKVEAPPPKVPKKREPVP--VPVALPQEEE---VLFEEEIVPEEEVL 10120
Query: 455 TEFQSPLPKETTAEEASAEIQLLAATEPPADETPAEARSPLSEETSAEEAHAEVQSPLAE 514
E + LP+E E+ P +E P P EE EE + +
Sbjct: 10121 PEEEEVLPEEEEVLPEEEEVL------PEEEEIP-----PEEEEVPPEEEYVPEEEEFVP 10169
Query: 515 ETTAEEASAEIQLLAAIEAPADETPAEAQSPLSEETSAEEA-PAEVQSPSAKGVSIEEAP 573
E EE E++ + AP E + EEA PA+V K +EE
Sbjct: 10170 E---EEVLPEVKPKVPVPAPVPEIKKKVTEKKVVIPKKEEAPPAKVPEVPKK---VEEKR 10223
Query: 574 LELQPPSGEETTAEEASAAIQLLAATEASAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAE 633
+ L P EE E + + S EE P E PP+ E EV PP E +
Sbjct: 10224 IIL--PKEEEVLPVEVTEEPE---EEPISEEEIPEE---PPSIEEVEEVAPPRVPEVIKK 10275
Query: 634 VQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQSLPAEETPIE 693
P P +V+ PPA+ + + P E+ P VQ E PA+V +P ++ P +
Sbjct: 10276 AVPEAPTPVPKKVEAPPAKVS----KKIPEEKVPVPVQ--KKEAPPAKVPEVP-KKVPEK 10328
Query: 694 ETLAAVHS--PPAD--DVPAEEASVDKHSPPADLLLTEEFPIGEASAEVSPPPSEQTPED 749
+ L PPA V E+ SV ++++ E + AEV E+ PE+
Sbjct: 10329 KVLVPKKEAVPPAKGRTVLEEKVSVAFRQ---EVVVKERLELEVVEAEV-----EEIPEE 10380
Query: 750 EALVENVSTEFQSPQVAGIPA-VKLGSVVLEGEAKFEEVSKINSVLK 795
E E V F+ + + +KL +E E + E+V ++ V +
Sbjct: 10381 EEFHE-VEEYFEEGEFHEVEEFIKLEQHRVEEEHRVEKVHRVIEVFE 10426
Score = 102 bits (255), Expect = 1e-21
Identities = 170/792 (21%), Positives = 290/792 (36%), Gaps = 111/792 (14%)
Query: 12 EKKKHMAIPKSSSPKATHRIGNTSGSKGSYSAKAYESIRVSSELQQ----TWTKRKHGQE 67
+ KK +A PK +P+ + AKA E I VSS+ ++ T T++K Q+
Sbjct: 8992 DAKKVVAKPKEMTPRE-EIVKKPPPPTTLIPAKAPEIIDVSSKAEEVKIMTITRKKEVQK 9050
Query: 68 MTSKSLQTDTIVEEKKEVKL-----------VEETVVP------EEKSADVREAAIELPE 110
+ V ++K V + VE P EE D E +E +
Sbjct: 9051 EKEAVYEKKQAVHKEKRVFIESFEEPYDELEVEPYTEPFEQPYYEEPDEDYEEIKVEAKK 9110
Query: 111 SVQDVEIPPNIPSVQLKMDRSQQTSRTGYWTMMNIPPVEKVDKEQQTYFSESEIVVISRP 170
V + E + Q +R + GY ++ ++E + + E E++ + +
Sbjct: 9111 EVHE-EWEEDFEEGQEYYEREE-----GY---------DEGEEEWEEAYQEREVIQVQKE 9155
Query: 171 ---DSSSTKSKEDALKHKSSGKIFASEHPEFQPATNSNEEIGQKNISRTSFTQETKKGPP 227
+S K + K+ + P + ++ + ++ + T + +KK P
Sbjct: 9156 VYEESHERKVPAKVPEKKAPPPPKVIKKPVIEKIEKTSRRMEEEKVQVTKVPEVSKKIVP 9215
Query: 228 VLLEDELREEVTVPVVQEGSAVKKVASAEIE---PPSTEKFPAKIQPPLVEEATAKAEPR 284
+E + V KK+ +E + TE+ + P + +E + +
Sbjct: 9216 QKPSRTPVQEEVIEVKVPAVHTKKMVISEEKMFFASHTEEEVSVTVPEVQKEIVTEEKIH 9275
Query: 285 PAEETHVQVQPSTEETPDAEAATAVAENSV--KVQPPPAE--EAPLVEFPAEIQP-PSAE 339
A V+ P E P+ A VA + KV+PP + E P P E +P P +
Sbjct: 9276 VAISKRVEPPPKVPELPEKPAPEEVAPVPIPKKVEPPAPKVPEVPKKPVPEEKKPVPVPK 9335
Query: 340 ESPSVELLAEILPPSAEESPSEEPPAEILPPPAEKSPSVELLGEIRSPSAQKAPIEVQPL 399
+ P+ PP E P + P E +P P K + P QK + + +
Sbjct: 9336 KEPAA-------PPKVPEVPKKPVPEEKIPVPVAKKKEAP---PAKVPEVQKGVVTEEKI 9385
Query: 400 PAEGALEEAPAKVEPPTVEETLADVQPLLPEEAPREEARELQLSTAMETPAEEAPTEFQS 459
EE+P PP V E +P++ EE + + P + P +
Sbjct: 9386 TIVTQREESP----PPAVPE--------IPKKKVPEERKPVPRKEEEVPPPPKVPALPKK 9433
Query: 460 PLPKETTAEEASAEIQLLAATEPPADETPAEARSPLSEETSAEEAHAEVQSPLAEETTAE 519
P+P+E A + + A + P ++ + E+ E P E T
Sbjct: 9434 PVPEEKVA------VPVPVAKKAPPPRAEVSKKTVVEEKRFVAEEKLSFAVPQRVEVTRH 9487
Query: 520 EASAEIQLLAAIEAPADETPAEAQSPLSEETSAEEAPAEVQSPSAKGVSIEEAPL---EL 576
E SAE + + E + EE AE EV + V E+ + +
Sbjct: 9488 EVSAEEEWSYSEEEEGVSISVYREEEREEEEEAEVTEYEVMEEPEEYVVEEKLHIISKRV 9547
Query: 577 QPPSGEETTAEEASAAIQLLAATEASAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQP 636
+ E T +E ++ + PA+++ PP PA+V P + P + P
Sbjct: 9548 EAEPAEVTERQEKKIVLK---------PKIPAKIEEPP----PAKVPEAPKKIVPEKKVP 9594
Query: 637 PPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQSLPAEETPIEETL 696
P + +V PP E P +P P ++ P +V E PA+V + T E+ L
Sbjct: 9595 APVPK-KEKVPPPKVPEEPK--KPVPEKKVPPKV-IKMEEPLPAKVTERHMQITQEEKVL 9650
Query: 697 AAV---HSPPADDVPAE------EASVDK------HSPPADLLLTEEFPIGEASAEVSPP 741
AV +PP VP E E V K PPA + + + E + P
Sbjct: 9651 VAVTKKEAPPKARVPEEPKRAVPEEKVLKLKPKREEEPPAKVTEFRKRVVKEEKVSIEAP 9710
Query: 742 PSEQTPEDEALV 753
E P E +
Sbjct: 9711 KREPQPIKEVTI 9722
Score = 84.7 bits (208), Expect = 3e-16
Identities = 153/671 (22%), Positives = 246/671 (36%), Gaps = 83/671 (12%)
Query: 78 IVEEKKEVKLVEETVVPEEKSADVR-------EAAIELPESVQDVEIPPNIPSVQLKMDR 130
+VEEK V++ EE VP K +V E + +P + + PP +P ++
Sbjct: 10477 VVEEK--VRVPEEPRVPPTKVPEVLPPKEVVPEKKVPVPPAKKPEAPPPKVPEAPKEVVP 10534
Query: 131 SQQTSRTGYWTMMNIPPVEKVDKEQQTYFSESEI--VVISRPDSSSTKSKEDALKHKSSG 188
++ +PP KV + + E ++ + +P+S + E +
Sbjct: 10535 EKKVPVPPP-KKPEVPPT-KVPEVPKAAVPEKKVPEAIPPKPESPPPEVPEAPKEVVPEK 10592
Query: 189 KIFAS--EHPEFQPAT---NSNEEIGQKNISRTSFTQETKKGPPVLLEDELREEVTVPVV 243
K+ A+ + PE P E + +K + PP E + VP V
Sbjct: 10593 KVPAAPPKKPEVTPVKVPEAPKEVVPEKKVPVP---------PPKKPEVPPTKVPEVPKV 10643
Query: 244 QEGSAVKKVASAEIEPPSTEKFPAKI----QPPLVEEATAKA--EPRPAEETHVQVQPST 297
AV + E PP E P ++ + +EE A+ EP PA V V P
Sbjct: 10644 ----AVPEKKVPEAIPPKPESPPPEVFEEPEEVALEEPPAEVVEEPEPAAPPQVTVPPK- 10698
Query: 298 EETPDAEAATAVAENS----VKVQPPPAEEAPLVEFPAEI-QPPSAEESPSVELLAEILP 352
+ P+ +A VA+ VKV P E P + P + + P A + E+ E++P
Sbjct: 10699 KPVPEKKAPAVVAKKPELPPVKVPEVPKEVVPEKKVPLVVPKKPEAPPAKVPEVPKEVVP 10758
Query: 353 PSAEESPS--EEPPAEILPPPAEKSPSVELLGEIRSPS-AQKAPIEVQPLPAEGALEE-- 407
P E PPA++ P K P +E + P A+ P EV P E A EE
Sbjct: 10759 EKKVAVPKKPEVPPAKV--PEVPKKPVLEEKPAVPVPERAESPPPEVYEEPEEIAPEEEI 10816
Query: 408 APAKVEP-PTVEETLADVQPLLPEEAPREEARELQLSTAMETPAEEAPTEFQSPLPKETT 466
AP + +P P EE +V P E P++ E ++ P + P ++P PKE
Sbjct: 10817 APEEEKPVPVAEEEEPEVPPPAVPEEPKKIIPEKKV------PVIKKP---EAPPPKEPE 10867
Query: 467 AEEASAEIQLLAATEPPADETPAEARSPLSEETSAEEAHAEVQSPLAEETTAEEASAEIQ 526
E+ + +L PP PA + + E+ +A + + P + + ++
Sbjct: 10868 PEKVIEKPKLKPRPPPPP---PAPPKEDVKEKIFQLKAIPKKKVPEKPQVPEKVELTPLK 10924
Query: 527 LLAAIEAPADETPAEAQSPLSEET--SAEEAPAEVQSPSAKGVSIEEAPLELQPPSGEET 584
+ + P P E S E + P + +E+ P
Sbjct: 10925 VPGGEKKVRKLLPERKPEPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPK 10984
Query: 585 TAEEASAAIQLLAATEASAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPA 644
EE + + E E + PA PA P E ++PPP E P
Sbjct: 10985 PVEEVE--VPTVTKRERKIPEPTKVPEIKPAIPLPAPEPKPKPEAEVKTIKPPPVEPEPT 11042
Query: 645 EVQPP---PAEEAPAEVQPPPAEEA-------------PAEVQPPPAEEAPAEVQSLPAE 688
+ P P AE + P E A P+ ++ + P P +
Sbjct: 11043 PIAAPVTVPVVGKKAEAKAPKEEAAKPKGPIKGVPKKTPSPIEAERRKLRPGSGGEKPPD 11102
Query: 689 ETPIEETLAAV 699
E P L AV
Sbjct: 11103 EAPFTYQLKAV 11113
Score = 81.6 bits (200), Expect = 3e-15
Identities = 132/558 (23%), Positives = 204/558 (36%), Gaps = 114/558 (20%)
Query: 292 QVQPSTEETPDAEAATAVAENSVKVQPP--PAEEAPLVEFPAEIQPPSAEESPSVELLAE 349
+++P E AE E ++++PP P P+ P PP EE P
Sbjct: 8908 RLEPRGEARSTAELYLTTKEIKLELKPPDIPDSRVPIPTMPIRAVPP--EEIP------- 8958
Query: 350 ILPPSAEESPSEEPPAEIL-PPPAEKSPSVELLGEIRSPSAQKAPIEVQPLPAEGALEEA 408
P PP +L P P EK P + + E+ + +K +V P E E
Sbjct: 8959 ---------PVVAPPIPLLLPTPEEKKPPPKRI-EVTKKAVKKDAKKVVAKPKEMTPREE 9008
Query: 409 PAKVEPPTVEETLADVQPLLPEEAPREEARELQLSTAMETPAE-EAPTEFQSPLPKE--- 464
K PP A ++ + EE + + ++ E E EA E + + KE
Sbjct: 9009 IVKKPPPPTTLIPAKAPEIIDVSSKAEEVKIMTITRKKEVQKEKEAVYEKKQAVHKEKRV 9068
Query: 465 --TTAEEASAEIQLLAATEP-----------PADETPAEARSPLSEETSAEEAHAEVQSP 511
+ EE E+++ TEP +E EA+ + EE EE E Q
Sbjct: 9069 FIESFEEPYDELEVEPYTEPFEQPYYEEPDEDYEEIKVEAKKEVHEEW--EEDFEEGQEY 9126
Query: 512 LAEETTAEEASAEIQLLAAIEAPADETPAEAQSPLSEETSAEEAPAEVQSPSAKGVSIEE 571
E +E E + EA + + Q + EE+ + PA+V A
Sbjct: 9127 YEREEGYDEGEEEWE-----EAYQEREVIQVQKEVYEESHERKVPAKVPEKKA-----PP 9176
Query: 572 APLELQPP---SGEETTAEEASAAIQLLAATEASAEEAPAEVQPPPAEEAPAEVQPPP-- 626
P ++ P E+T+ +Q+ E S + P + P +E EV+ P
Sbjct: 9177 PPKVIKKPVIEKIEKTSRRMEEEKVQVTKVPEVSKKIVPQKPSRTPVQEEVIEVKVPAVH 9236
Query: 627 ----------------AEEAPAEVQPPPAEEAPAE----------VQPP------PAEEA 654
EE + P +E E V+PP P + A
Sbjct: 9237 TKKMVISEEKMFFASHTEEEVSVTVPEVQKEIVTEEKIHVAISKRVEPPPKVPELPEKPA 9296
Query: 655 PAEVQPPPAEEAPAEVQPPPAEEAPAEVQSLPAEETPI----EETLAAVHSP--PADDVP 708
P EV P P P +V+PP + + +P E+ P+ +E A P P VP
Sbjct: 9297 PEEVAPVP---IPKKVEPPAPKVPEVPKKPVPEEKKPVPVPKKEPAAPPKVPEVPKKPVP 9353
Query: 709 AEEASV----DKHSPPADL------LLTEEFPIGEASAEVSPPPS------EQTPEDEAL 752
E+ V K +PPA + ++TEE E SPPP+ ++ PE+
Sbjct: 9354 EEKIPVPVAKKKEAPPAKVPEVQKGVVTEEKITIVTQREESPPPAVPEIPKKKVPEERKP 9413
Query: 753 VENVSTEF-QSPQVAGIP 769
V E P+V +P
Sbjct: 9414 VPRKEEEVPPPPKVPALP 9431
Score = 79.7 bits (195), Expect = 1e-14
Identities = 170/809 (21%), Positives = 281/809 (34%), Gaps = 176/809 (21%)
Query: 61 KRKHGQEMTSKSLQTDTIVEEKKEVKLVEET----VVPEEKSADVREAAIELPESVQDVE 116
K+K +Q + EEK + E VPE V E +P ++V
Sbjct: 9363 KKKEAPPAKVPEVQKGVVTEEKITIVTQREESPPPAVPEIPKKKVPEERKPVPRKEEEVP 9422
Query: 117 IPPNIPSVQLKMDRSQQTSRTGYWTMMNIPPVEKVDK----EQQTYFSESEIVVISRPDS 172
PP +P++ K ++ + PP +V K E++ + +E ++ S
Sbjct: 9423 PPPKVPALPKKPVPEEKVAVPVPVAKKAPPPRAEVSKKTVVEEKRFVAEEKL-------S 9475
Query: 173 SSTKSKEDALKHKSSGKIFASEHPEFQPATNSNEEIGQKNISRTSFTQETKKGPPVLLED 232
+ + + +H+ S + + + S EE G +S + + +E + E+
Sbjct: 9476 FAVPQRVEVTRHEVSAE---------EEWSYSEEEEG---VSISVYREEER-------EE 9516
Query: 233 ELREEVTVPVVQEGSAVKKVASAEIEPPSTEKFPAKIQPPLVEEATAKAEPRPAEETHVQ 292
E EVT V E EP E++ + + ++ + + E PAE T Q
Sbjct: 9517 EEEAEVTEYEVME------------EP---EEYVVEEKLHIISK---RVEAEPAEVTERQ 9558
Query: 293 VQPSTEETPDAEAATAVAENSVKVQPPPAEEAPLVEFPAEIQPPSAEESPSVELLAEILP 352
+ + P A K++ PP + P E P +I P +P V ++ P
Sbjct: 9559 EKKIVLK-PKIPA---------KIEEPPPAKVP--EAPKKIVPEKKVPAP-VPKKEKVPP 9605
Query: 353 PSAEESPSEEPPAEILPPPA----EKSPSVELLGEIRSPSAQKAPIEV--QPLPAEGALE 406
P E P + P + +PP E P+ ++ +K + V + P + +
Sbjct: 9606 PKVPEEPKKPVPEKKVPPKVIKMEEPLPAKVTERHMQITQEEKVLVAVTKKEAPPKARVP 9665
Query: 407 EAPAKVEPPTVEETLADVQPLLPEEAPREEARELQLSTAMETPAEEAPTEFQSPLPKET- 465
E P + P EE + ++P EE P + + E + EAP P+ + T
Sbjct: 9666 EEPKRAVP---EEKVLKLKPKREEEPPAKVTEFRKRVVKEEKVSIEAPKREPQPIKEVTI 9722
Query: 466 --------TAEEASAEIQLLAATE--PPADETPAEARSPLSEETSAEEAH---------- 505
T EE + +Q E D E P E EE
Sbjct: 9723 MEEKERAYTLEEEAVSVQREEEYEEYEEYDYKEFEEYEPTEEYDQYEEYEEREYERYEEH 9782
Query: 506 ----AEVQSPLAEETTAE--------------------EASAEIQLLAAIEAPADETPAE 541
E + P+ + E E + + ++ P + P E
Sbjct: 9783 EEYITEPEKPIPVKPVPEEPVPTKPKAPPAKVLKKAVPEEKVPVPIPKKLKPPPPKVPEE 9842
Query: 542 AQSPLSEE---TSAEEAPAEVQSPSAK-----------------------GVSIEEAPLE 575
+ E+ + + +V P+AK V + E P E
Sbjct: 9843 PKKVFEEKIRISITKREKEQVTEPAAKVPMKPKRVVAEEKVPVPRKEVAPPVRVPEVPKE 9902
Query: 576 LQPPS----------GEETTAEEASAAI---QLLAATEASAEEAPAEVQPPPAEEAPAEV 622
L+P EE EE I + E P +V P + P E
Sbjct: 9903 LEPEEVAFEEEVVTHVEEYLVEEEEEYIHEEEEFITEEEVVPVIPVKVPEVPRKPVPEEK 9962
Query: 623 QP---PPAEEAP----AEVQPPPAEEAPAEV----QPPPAEEAPAEVQPPPAEEAPAEVQ 671
+P P +EAP EV P E+ P + +PPPA+ +P P E+ P V
Sbjct: 9963 KPVPVPKKKEAPPAKVPEVPKKPEEKVPVLIPKKEKPPPAKVPEVPKKPVPEEKVPVPV- 10021
Query: 672 PPPAEEAPAEVQSLPAEETPIEETLA----AVHSPPA--DDVPAEEASVDKHSPPADLLL 725
P E PA+V +P + P ++ V +PPA +VP + +K P +
Sbjct: 10022 PKKVEAPPAKVPEVPKKPVPEKKVPVPAPKKVEAPPAKVPEVPKKLIPEEKKPTPVPKKV 10081
Query: 726 TEEFPIGEASAEVSPPPSEQTPEDEALVE 754
P E P P E+E L E
Sbjct: 10082 EAPPPKVPKKREPVPVPVALPQEEEVLFE 10110
Score = 41.6 bits (96), Expect = 0.003
Identities = 66/266 (24%), Positives = 97/266 (36%), Gaps = 44/266 (16%)
Query: 451 EEAPTEFQSPLPKETTAEEASAEIQLLAATEPPADETPAEARSPLSEETSA-----EEAH 505
EE P +S P E T EA A +E A + E +S ++E + A
Sbjct: 32478 EEVP---RSVFP-ELTRTEAYAVSSFKKTSEMEASSSVREVKSQMTETRESLSSYEHSAS 32533
Query: 506 AEVQSPLAEETTAEEASAEIQLLAAIEA-----PADETPAEAQSP-LSEETSAEEAPAE- 558
AE++S EE + EE S ++ + A P T E +S S +T E P
Sbjct: 32534 AEMKSAALEEKSLEEKSTTRKIKTTLAARILTKPRSMTVYEGESARFSCDTDGEPVPTVT 32593
Query: 559 -VQSPSAKGVSIEEAPLELQPPSGEETTAEEASAAIQLLAATEASAEEAPAE-------- 609
++ S + S E ++ +AS E S + AE
Sbjct: 32594 WLRKGQVLSTSARHQVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQKA 32653
Query: 610 ------VQPPPAEEAP-AEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPP 662
V PP ++P V+ P A ++P V+ P P +P E +P P
Sbjct: 32654 RVTEKAVTSPPRVKSPEPRVKSPEAVKSPKRVKSPEPSH--------PKAVSPTETKPTP 32705
Query: 663 AEEAPAEVQPPPAEEAPAEVQSLPAE 688
E +VQ P P Q L AE
Sbjct: 32706 TE----KVQHLPVSAPPKITQFLKAE 32727
Score = 33.5 bits (75), Expect = 0.83
Identities = 50/268 (18%), Positives = 103/268 (38%), Gaps = 10/268 (3%)
Query: 340 ESPSVELLAEILPPSAEESPSEEPPAEILPPPAEKSPSVELLGEIRSPSAQK--APIEVQ 397
++ S+ + ++ +A + + P I P P +SP+ + + Q+ +PI
Sbjct: 230 DARSIATVEMVIDGAAGQQLPHKTPPRIPPKPKSRSPTPPSIAAKAQLARQQSPSPIRHS 289
Query: 398 PLPAEGALEEAPAKVEPPTVEETLADVQPLLPEEAPREEARELQLSTAMETPAEEAPTEF 457
P P P+ V + ++ P+ +P R+ Q ST P E P +
Sbjct: 290 PSPVRHVRAPTPSPVRSVSPAARIS-TSPIRSVRSPL-LMRKTQASTVATGP--EVPPPW 345
Query: 458 QSPLPKETTAEEASAEIQLLAATEPPADETPAEARSPLSEETSAEEAHAEVQSPLAEETT 517
+ +++E E L +T+ +E E R + E+ + A S A +
Sbjct: 346 KQEGYVASSSEAEMRETTLTTSTQIRTEER-WEGRYGVQEQVTISGAAGAAASVSASASY 404
Query: 518 AEEASAEIQLLAAIEAPADETPAEAQSPLSEETSAEEAPAEVQSPSAKGVSIEEAPLELQ 577
A EA A ++ AD++ A A + + + P + + + +Q
Sbjct: 405 AAEAVA--TGAKEVKQDADKSAAVATVVAAVDMARVREPV-ISAVEQTAQRTTTTAVHIQ 461
Query: 578 PPSGEETTAEEASAAIQLLAATEASAEE 605
P + E +A +++ A + + E+
Sbjct: 462 PAQEQVRKEAEKTAVTKVVVAADKAKEQ 489
Score = 31.2 bits (69), Expect = 4.1
Identities = 23/93 (24%), Positives = 39/93 (41%), Gaps = 5/93 (5%)
Query: 394 IEVQPLPAEGALEEAPAKVEPPTVEETLADVQPLLPEEAPREEARELQLS-----TAMET 448
+ + +P E L+ + V + V L + E+A E+QL+ T
Sbjct: 12219 LSYEDIPVEWYLKGKKLEPSDKVVPRSEGKVHTLTLRDVKLEDAGEVQLTAKDFKTHANL 12278
Query: 449 PAEEAPTEFQSPLPKETTAEEASAEIQLLAATE 481
+E P EF PL +T E A+A ++ + E
Sbjct: 12279 FVKEPPVEFTKPLEDQTVEEGATAVLECEVSRE 12311
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 124 bits (310), Expect = 5e-28
Identities = 185/796 (23%), Positives = 276/796 (34%), Gaps = 73/796 (9%)
Query: 20 PKSSSPKATHRIGNTSGSKGSYS-AKAYESIRVSSELQQTWTKRKHGQEMTS---KSLQT 75
PK + K T ++ + +S ++ ES SS + T RK S + LQ
Sbjct: 96 PKPPNKKKTKKVIESEEITEEHSVSENQESSSSSSSSSSSSTIRKIKSSKNSAANRELQK 155
Query: 76 DTIVEEKKEVKLVEETVVPEEKSADVREAAIELPESVQDVEIPPNIPSVQLKMDRSQQ-T 134
V++ K+ + ++ P K V EA L V P + K+ S + T
Sbjct: 156 KLKVKDNKKNRTKKK---PTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKIT 212
Query: 135 SRTGYWTMMNIPPVEKVDKE------QQTYFSESEIVVISRPDSSSTKSKEDALKHKSS- 187
+ ++PP KE ++T E ++ S+ K K + K S
Sbjct: 213 TAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSI 272
Query: 188 -----------GKIFASEHPEFQPATNSNEEIGQKNISRTSFTQETKKGPPVLLEDELRE 236
K+ A P+ + T K + T+ + P ++
Sbjct: 273 EKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKS 332
Query: 237 EVTVPVVQEGSAVKKVASAEIEP-PSTEKFPAKIQPPLVEEATAKAEPRPAEETHVQVQP 295
T P + K + EP P+T K PA P T K EP P T + P
Sbjct: 333 APTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTK-EPAP---TTTKSAP 388
Query: 296 STEETPDAEAATAVAENSVKVQPPPAEEAPLVEFPAEIQPPSAEESPSVELLAEILPPSA 355
+T + P A + K P + P P E P + E +P+ + P+A
Sbjct: 389 TTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTP---KEPAPTA 445
Query: 356 EESPSEEPPAEILP-------PPAEKSPSVELLGEIRSPSAQKAPIEVQPLPAEGALEEA 408
+ P+ P E P P K PS E + + AP + PA + A
Sbjct: 446 PKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKE-PAPTTTKSA 504
Query: 409 PAKVEPPTVEETLADVQPLLPEE----APREEARELQLSTAMETPAEEAPTEFQSPLPKE 464
P + P+ T + P P+E P++ A A TP E APT + P P
Sbjct: 505 PTTPKEPS-PTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAP-- 561
Query: 465 TTAEEASAEIQLLAATEPPADETPA--EARSPLSEETSAEEAHAEVQSPLAEE---TTAE 519
TT +E + A P TP E +P + E A E+ EE TT E
Sbjct: 562 TTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPE 621
Query: 520 EASAEIQLLAAIEAPADETPAEAQ--SPLSEETSAEEAPAEVQSPSAKGVSIEEAPLELQ 577
E + AA P + P + +P + + A P E + KG AP L+
Sbjct: 622 EPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGT----APTTLK 677
Query: 578 PPSGEETTAEEASAAIQLLAATEASAEEAPAEVQPPPAEEAPAEVQPP-PAEEAPAEVQP 636
P+ T + A +L T + P + A P PA P E P
Sbjct: 678 EPA---PTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAP 734
Query: 637 PPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQSLPAEETPIEETL 696
+ PA P + P P E AP + P + PA TP +ET
Sbjct: 735 TTPKGTAPTTLKEPAPTTPKK--PAPKELAPTTTKGP-----TSTTSDKPAPTTP-KETA 786
Query: 697 AAVHSPPADDVPAEEASVDKHSPPADLLLTEEFPIGEASAEVSPPPSEQTPEDEALVENV 756
PA P + A +PP + + P E TPE A
Sbjct: 787 PTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPK 846
Query: 757 STEFQSPQVAGIPAVK 772
+ E SP+ G+P K
Sbjct: 847 ALE-NSPKEPGVPTTK 861
Score = 105 bits (261), Expect = 2e-22
Identities = 172/721 (23%), Positives = 251/721 (34%), Gaps = 99/721 (13%)
Query: 72 SLQTDTIVEEKKEVKLVEETVVPEEKSADVREAAIELPESVQDVE------IPPNIPSVQ 125
S +T V ++ V+ E T ++ S D +E E+ Q +E + P +
Sbjct: 230 SKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKET-QSIEKTSAKDLAPTSKVLA 288
Query: 126 LKMDRSQQTSRTGYWTMMNIP-------PVEKVDKEQQTYFSESEIVVISRPDSSSTKSK 178
+++ T++ T P P KE +S P ++TKS
Sbjct: 289 KPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSA 348
Query: 179 EDALKHKS--SGKIFASEHPEFQPATNSNEEIGQKNISRTSFTQE----TKKGPPVLLED 232
K + + K A P+ T + E S + +E T K P
Sbjct: 349 PTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPK 408
Query: 233 ELREEVTVPVVQEGSAVKKVASAEIEP-PSTEKFPAKIQPPLVEEATAKAEPRPAEETHV 291
E T P + K+ A EP P+T K PA P T K PA T
Sbjct: 409 E--PAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPK---EPAPTTPK 463
Query: 292 QVQPSTEETPDAEAATAVAENSVKVQPPPAEE-APLVEFPAEIQPPSAEESPSVELLAEI 350
+ P+T + P A + K P +E AP A P+ + PS E
Sbjct: 464 EPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSA----PTTPKEPSPTTTKEP 519
Query: 351 LP-------PSAEESPSEEPPAEILPP-PAEKSPSVELLGEIRSPS--AQKAPIEVQPLP 400
P P+ + P+ P E P P E +P+ +P A P E P
Sbjct: 520 APTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTT 579
Query: 401 AEGALEEAPAKVEPPTVEE----TLADVQPLLPEE----APREEARELQLSTAMETPAEE 452
+ P K+ P T E+ T ++ P PEE P E A + A TP E
Sbjct: 580 PKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEP 639
Query: 453 APTEFQSPLPKETTAEEASAEIQLLAATEPPADETPAEARSPLSEETSAEEAHAEVQSPL 512
APT + P P TT +E + A P P + P + T + A E L
Sbjct: 640 APTTPKEPAP--TTPKEPAPTTPKETAPTTPKGTAPTTLKEP-APTTPKKPAPKE----L 692
Query: 513 AEETTAEEASAEIQLLAAIEAPADETPAEAQSPLSEETSAEEAPAEVQSPSAKGVSIEEA 572
A TT E S + PA TP + +P + + A P E + KG A
Sbjct: 693 APTTTKEPTS------TTCDKPAPTTP-KGTAPTTPKEPAPTTPKEPAPTTPKGT----A 741
Query: 573 PLELQPPSGEETTAEEASAAIQLLAATEASAEEAPAEVQPPPAEEAPAEVQPPPAEEAPA 632
P L+ P A + AP E+ P + + PA P
Sbjct: 742 PTTLKEP------------------APTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPK 783
Query: 633 EVQP-PPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQSLPAEETP 691
E P P E AP P + AP + PP +EV P + P + P E TP
Sbjct: 784 ETAPTTPKEPAPT----TPKKPAPTTPETPP--PTTSEVSTPTTTKEPTTIHKSPDESTP 837
Query: 692 IEETLAAVHSPPADDVPAEEASVDKHSPPA----DLLLTEEFPIGEASAEVSPPPSEQTP 747
L+A +P A + +E V PA ++ T + E +P + P
Sbjct: 838 ---ELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAP 894
Query: 748 E 748
+
Sbjct: 895 K 895
Score = 89.0 bits (219), Expect = 2e-17
Identities = 150/652 (23%), Positives = 231/652 (35%), Gaps = 92/652 (14%)
Query: 168 SRPDSSSTKSKEDALKHKSSGKIFASEHPEFQPATNSNEEIGQKNISRTSFT--QETKKG 225
S+ S+TK K + K+ SE + + + N+E + S +S + ++ K
Sbjct: 85 SQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSSSSSSSSSTIRKIKSS 144
Query: 226 PPVLLEDELREEVTV----------------PVVQEGSAVKKVASAEIEPPSTEKFPAKI 269
EL++++ V PVV E + ++ P T
Sbjct: 145 KNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNK 204
Query: 270 QPPLVEEATAKA-EPRPA----------------EETHVQVQPST----EETPDAEAATA 308
+ TAK PRP+ +ET V+ + +T + + D + T
Sbjct: 205 VSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTT 264
Query: 309 VAENSVKVQPPPAEE-APLVEFPAEIQPPSAEESPSVELLAEILP-PSAEESPSEEPPAE 366
A+ + ++ A++ AP + A+ P + + L P P+ + P+ P E
Sbjct: 265 SAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKE 324
Query: 367 ILPPPAEKSPSV-ELLGEIRSPSAQKAPIEVQPLPAEGALEEAPAKVEPPTVEETLADVQ 425
P + +P+ + + SA P E P + P + P T +E
Sbjct: 325 PTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTT 384
Query: 426 PLLPEEAPREEARELQLSTAMETPAEEAPTEFQSPLPKETTAEEASAEIQLLAATEPPAD 485
P P+E A A TP E APT + P P TT +E + + A T P +
Sbjct: 385 KSAPT-TPKEPAPTTPKKPAPTTPKEPAPTTPKEPTP--TTPKEPAPTTKEPAPTTPK-E 440
Query: 486 ETPAEARSPLSEETSAEEAHAEVQSPLAEETTAEEASAEIQLLAAIEAPADETPAE-AQS 544
P + P + T E A + P A TT E P+ TP E A +
Sbjct: 441 PAPTAPKKP-APTTPKEPAPTTPKEP-APTTTKE--------------PSPTTPKEPAPT 484
Query: 545 PLSEETSAEEAPAEVQSPSAKGVSIEEAPLELQPPSGEETTAEEASAAIQLLAATEASAE 604
+ + PA + SA E +P + P+ TT +E + A E
Sbjct: 485 TTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPA--PTTPKEPAPTTPKKPAPTTPKE 542
Query: 605 EAPAEVQPP-------PAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAE 657
AP + P PA P E PA P E P P ++ P E+
Sbjct: 543 PAPTTPKEPAPTTTKKPAPTTPKE----PAPTTPKETAP----TTPKKLTPTTPEKLAPT 594
Query: 658 VQPPPAEEAPAEVQPPPAEEAPAEVQSLPAEETPIEETLAAVHSP--PADDVPAEEASVD 715
PA P E+ P EE PA TP AA ++P PA P E A
Sbjct: 595 TPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTP---KAAAPNTPKEPAPTTPKEPAPTT 651
Query: 716 KHSP----PADLLLTEEFPIGEASAEVSPPPSEQTPEDEALVENVSTEFQSP 763
P P + T P G A + P+ TP+ A E T + P
Sbjct: 652 PKEPAPTTPKETAPTT--PKGTAPTTLK-EPAPTTPKKPAPKELAPTTTKEP 700
Score = 63.2 bits (152), Expect = 1e-09
Identities = 101/452 (22%), Positives = 166/452 (36%), Gaps = 76/452 (16%)
Query: 358 SPSEEPPAEILPPPAEKSPSVELLGEIRSPSAQ-----KAPIEVQPLPAEGAL---EEAP 409
+P+ P ++ PPP+ S +++ + RSP K IE + + E ++ +E+
Sbjct: 68 NPTSPPSSKKAPPPSGASQTIKSTTK-RSPKPPNKKKTKKVIESEEITEEHSVSENQESS 126
Query: 410 AKVEPPTVEETLADVQPLLPEEAPREEARELQLSTAMETPAEEAPTEFQSPLPKETTAEE 469
+ + T+ ++ A RE ++L++ + ++ PT PK +E
Sbjct: 127 SSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPT------PKPPVVDE 180
Query: 470 ASAEIQLLAATEPPADETPAEARSPLSEETSAEEAHAEVQSPLAEETTAEEASAEIQLLA 529
A + + D + +P +TS + + SP + TTA+ + L
Sbjct: 181 AGSGL----------DNGDFKVTTP---DTSTTQHNKVSTSP--KITTAKPINPRPSL-- 223
Query: 530 AIEAPADETPAEAQSPLSEETSAEEAPAEVQSPSAKGVSIEEAPLELQPPSGEETTAEEA 589
P +T E +++ET+ E + E+ + S E+T+A++
Sbjct: 224 ---PPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDL 280
Query: 590 SAAIQLLAATEASAE---EAPAEVQPP-PAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAE 645
+ ++LA AE + PA P P P E PA P E P + AP
Sbjct: 281 APTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKE----PASTTPKEPTPTTIKSAPTT 336
Query: 646 VQPP-----------PAEEAPAEVQPP----PAEEAPAEVQPP-----------PAEEAP 679
+ P P E AP + P P E AP + P P E AP
Sbjct: 337 PKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAP 396
Query: 680 AEVQSLPAEETPIEETLAAVHSPPADDVPAEEASVDKHSPPADLLLTEEFPIGEASAEVS 739
+ PA TP +E P P E A K P T + P A + +
Sbjct: 397 TTPKK-PAPTTP-KEPAPTTPKEPTPTTPKEPAPTTKEPAPT----TPKEPAPTAPKKPA 450
Query: 740 P-PPSEQTPEDEALVENVSTEFQSPQVAGIPA 770
P P E P +T+ SP PA
Sbjct: 451 PTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPA 482
Score = 58.2 bits (139), Expect = 3e-08
Identities = 91/418 (21%), Positives = 145/418 (34%), Gaps = 47/418 (11%)
Query: 239 TVPVVQEGSAVKKVASAEIEP-PSTEKFPA--KIQPPLVEEATAKAEPRPAEETHVQVQP 295
T P +G+A + EP P+T K PA ++ P +E T+ +PA T P
Sbjct: 663 TAPTTPKGTAPTTLK----EPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAP 718
Query: 296 STEETPDAEAATAVAENSVKVQPP-----PAEEAPLVEFPAEIQPPSAE-------ESPS 343
+T + P A + K P PA P P E+ P + + + P+
Sbjct: 719 TTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPA 778
Query: 344 VELLAEILPPSAEESPSEEPPAEILPPPAEKSPSVELLGEIRSPSAQKAPIEVQPLPAEG 403
E P + +E P+ P + P E P E+ +P+ K P + P E
Sbjct: 779 PTTPKETAPTTPKE-PAPTTPKKPAPTTPETPPPTT--SEVSTPTTTKEPTTIHKSPDES 835
Query: 404 -----------ALEEAPAKVEPPTVEETLADVQPLLPEEAPREEARELQLSTAMETPAEE 452
ALE +P + PT +T A +P + A +++ E L T ET
Sbjct: 836 TPELSAEPTPKALENSPKEPGVPTT-KTPAATKPEMTTTA-KDKTTERDLRTTPET---- 889
Query: 453 APTEFQSPLPKETTAEEASAEIQLLAATEPPADETPAEARSPLSEETSAEEAHAEVQSPL 512
T + KET + AT T + +P T A +
Sbjct: 890 --TTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTT 947
Query: 513 AEETTAEEASAEIQLLAAIEAPADETPAEAQSPLSEETSAEEAPAEVQSPS----AKGVS 568
+ T E + + A + A + A P + T A + P + P +
Sbjct: 948 KKTITTTEIMNKPEETAKPKDRATNSKATTPKP-QKPTKAPKKPTSTKKPKTMPRVRKPK 1006
Query: 569 IEEAPLELQPPSGE-ETTAEEASAAIQLLAATEASAEEAPAEVQPPPAEEAPAEVQPP 625
P ++ E T+ A A +Q + EV P + AE + P
Sbjct: 1007 TTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSEDAGGAEGETP 1064
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 124 bits (310), Expect = 5e-28
Identities = 185/796 (23%), Positives = 276/796 (34%), Gaps = 73/796 (9%)
Query: 20 PKSSSPKATHRIGNTSGSKGSYS-AKAYESIRVSSELQQTWTKRKHGQEMTS---KSLQT 75
PK + K T ++ + +S ++ ES SS + T RK S + LQ
Sbjct: 137 PKPPNKKKTKKVIESEEITEEHSVSENQESSSSSSSSSSSSTIRKIKSSKNSAANRELQK 196
Query: 76 DTIVEEKKEVKLVEETVVPEEKSADVREAAIELPESVQDVEIPPNIPSVQLKMDRSQQ-T 134
V++ K+ + ++ P K V EA L V P + K+ S + T
Sbjct: 197 KLKVKDNKKNRTKKK---PTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKIT 253
Query: 135 SRTGYWTMMNIPPVEKVDKE------QQTYFSESEIVVISRPDSSSTKSKEDALKHKSS- 187
+ ++PP KE ++T E ++ S+ K K + K S
Sbjct: 254 TAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSI 313
Query: 188 -----------GKIFASEHPEFQPATNSNEEIGQKNISRTSFTQETKKGPPVLLEDELRE 236
K+ A P+ + T K + T+ + P ++
Sbjct: 314 EKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKS 373
Query: 237 EVTVPVVQEGSAVKKVASAEIEP-PSTEKFPAKIQPPLVEEATAKAEPRPAEETHVQVQP 295
T P + K + EP P+T K PA P T K EP P T + P
Sbjct: 374 APTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTK-EPAP---TTTKSAP 429
Query: 296 STEETPDAEAATAVAENSVKVQPPPAEEAPLVEFPAEIQPPSAEESPSVELLAEILPPSA 355
+T + P A + K P + P P E P + E +P+ + P+A
Sbjct: 430 TTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTP---KEPAPTA 486
Query: 356 EESPSEEPPAEILP-------PPAEKSPSVELLGEIRSPSAQKAPIEVQPLPAEGALEEA 408
+ P+ P E P P K PS E + + AP + PA + A
Sbjct: 487 PKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKE-PAPTTTKSA 545
Query: 409 PAKVEPPTVEETLADVQPLLPEE----APREEARELQLSTAMETPAEEAPTEFQSPLPKE 464
P + P+ T + P P+E P++ A A TP E APT + P P
Sbjct: 546 PTTPKEPS-PTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAP-- 602
Query: 465 TTAEEASAEIQLLAATEPPADETPA--EARSPLSEETSAEEAHAEVQSPLAEE---TTAE 519
TT +E + A P TP E +P + E A E+ EE TT E
Sbjct: 603 TTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPE 662
Query: 520 EASAEIQLLAAIEAPADETPAEAQ--SPLSEETSAEEAPAEVQSPSAKGVSIEEAPLELQ 577
E + AA P + P + +P + + A P E + KG AP L+
Sbjct: 663 EPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGT----APTTLK 718
Query: 578 PPSGEETTAEEASAAIQLLAATEASAEEAPAEVQPPPAEEAPAEVQPP-PAEEAPAEVQP 636
P+ T + A +L T + P + A P PA P E P
Sbjct: 719 EPA---PTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAP 775
Query: 637 PPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQSLPAEETPIEETL 696
+ PA P + P P E AP + P + PA TP +ET
Sbjct: 776 TTPKGTAPTTLKEPAPTTPKK--PAPKELAPTTTKGP-----TSTTSDKPAPTTP-KETA 827
Query: 697 AAVHSPPADDVPAEEASVDKHSPPADLLLTEEFPIGEASAEVSPPPSEQTPEDEALVENV 756
PA P + A +PP + + P E TPE A
Sbjct: 828 PTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPK 887
Query: 757 STEFQSPQVAGIPAVK 772
+ E SP+ G+P K
Sbjct: 888 ALE-NSPKEPGVPTTK 902
Score = 105 bits (261), Expect = 2e-22
Identities = 172/721 (23%), Positives = 251/721 (34%), Gaps = 99/721 (13%)
Query: 72 SLQTDTIVEEKKEVKLVEETVVPEEKSADVREAAIELPESVQDVE------IPPNIPSVQ 125
S +T V ++ V+ E T ++ S D +E E+ Q +E + P +
Sbjct: 271 SKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKET-QSIEKTSAKDLAPTSKVLA 329
Query: 126 LKMDRSQQTSRTGYWTMMNIP-------PVEKVDKEQQTYFSESEIVVISRPDSSSTKSK 178
+++ T++ T P P KE +S P ++TKS
Sbjct: 330 KPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSA 389
Query: 179 EDALKHKS--SGKIFASEHPEFQPATNSNEEIGQKNISRTSFTQE----TKKGPPVLLED 232
K + + K A P+ T + E S + +E T K P
Sbjct: 390 PTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPK 449
Query: 233 ELREEVTVPVVQEGSAVKKVASAEIEP-PSTEKFPAKIQPPLVEEATAKAEPRPAEETHV 291
E T P + K+ A EP P+T K PA P T K PA T
Sbjct: 450 E--PAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPK---EPAPTTPK 504
Query: 292 QVQPSTEETPDAEAATAVAENSVKVQPPPAEE-APLVEFPAEIQPPSAEESPSVELLAEI 350
+ P+T + P A + K P +E AP A P+ + PS E
Sbjct: 505 EPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSA----PTTPKEPSPTTTKEP 560
Query: 351 LP-------PSAEESPSEEPPAEILPP-PAEKSPSVELLGEIRSPS--AQKAPIEVQPLP 400
P P+ + P+ P E P P E +P+ +P A P E P
Sbjct: 561 APTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTT 620
Query: 401 AEGALEEAPAKVEPPTVEE----TLADVQPLLPEE----APREEARELQLSTAMETPAEE 452
+ P K+ P T E+ T ++ P PEE P E A + A TP E
Sbjct: 621 PKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEP 680
Query: 453 APTEFQSPLPKETTAEEASAEIQLLAATEPPADETPAEARSPLSEETSAEEAHAEVQSPL 512
APT + P P TT +E + A P P + P + T + A E L
Sbjct: 681 APTTPKEPAP--TTPKEPAPTTPKETAPTTPKGTAPTTLKEP-APTTPKKPAPKE----L 733
Query: 513 AEETTAEEASAEIQLLAAIEAPADETPAEAQSPLSEETSAEEAPAEVQSPSAKGVSIEEA 572
A TT E S + PA TP + +P + + A P E + KG A
Sbjct: 734 APTTTKEPTS------TTCDKPAPTTP-KGTAPTTPKEPAPTTPKEPAPTTPKGT----A 782
Query: 573 PLELQPPSGEETTAEEASAAIQLLAATEASAEEAPAEVQPPPAEEAPAEVQPPPAEEAPA 632
P L+ P A + AP E+ P + + PA P
Sbjct: 783 PTTLKEP------------------APTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPK 824
Query: 633 EVQP-PPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQSLPAEETP 691
E P P E AP P + AP + PP +EV P + P + P E TP
Sbjct: 825 ETAPTTPKEPAPT----TPKKPAPTTPETPP--PTTSEVSTPTTTKEPTTIHKSPDESTP 878
Query: 692 IEETLAAVHSPPADDVPAEEASVDKHSPPA----DLLLTEEFPIGEASAEVSPPPSEQTP 747
L+A +P A + +E V PA ++ T + E +P + P
Sbjct: 879 ---ELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAP 935
Query: 748 E 748
+
Sbjct: 936 K 936
Score = 89.0 bits (219), Expect = 2e-17
Identities = 150/652 (23%), Positives = 231/652 (35%), Gaps = 92/652 (14%)
Query: 168 SRPDSSSTKSKEDALKHKSSGKIFASEHPEFQPATNSNEEIGQKNISRTSFT--QETKKG 225
S+ S+TK K + K+ SE + + + N+E + S +S + ++ K
Sbjct: 126 SQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSSSSSSSSSTIRKIKSS 185
Query: 226 PPVLLEDELREEVTV----------------PVVQEGSAVKKVASAEIEPPSTEKFPAKI 269
EL++++ V PVV E + ++ P T
Sbjct: 186 KNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNK 245
Query: 270 QPPLVEEATAKA-EPRPA----------------EETHVQVQPST----EETPDAEAATA 308
+ TAK PRP+ +ET V+ + +T + + D + T
Sbjct: 246 VSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTT 305
Query: 309 VAENSVKVQPPPAEE-APLVEFPAEIQPPSAEESPSVELLAEILP-PSAEESPSEEPPAE 366
A+ + ++ A++ AP + A+ P + + L P P+ + P+ P E
Sbjct: 306 SAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKE 365
Query: 367 ILPPPAEKSPSV-ELLGEIRSPSAQKAPIEVQPLPAEGALEEAPAKVEPPTVEETLADVQ 425
P + +P+ + + SA P E P + P + P T +E
Sbjct: 366 PTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTT 425
Query: 426 PLLPEEAPREEARELQLSTAMETPAEEAPTEFQSPLPKETTAEEASAEIQLLAATEPPAD 485
P P+E A A TP E APT + P P TT +E + + A T P +
Sbjct: 426 KSAPT-TPKEPAPTTPKKPAPTTPKEPAPTTPKEPTP--TTPKEPAPTTKEPAPTTPK-E 481
Query: 486 ETPAEARSPLSEETSAEEAHAEVQSPLAEETTAEEASAEIQLLAAIEAPADETPAE-AQS 544
P + P + T E A + P A TT E P+ TP E A +
Sbjct: 482 PAPTAPKKP-APTTPKEPAPTTPKEP-APTTTKE--------------PSPTTPKEPAPT 525
Query: 545 PLSEETSAEEAPAEVQSPSAKGVSIEEAPLELQPPSGEETTAEEASAAIQLLAATEASAE 604
+ + PA + SA E +P + P+ TT +E + A E
Sbjct: 526 TTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPA--PTTPKEPAPTTPKKPAPTTPKE 583
Query: 605 EAPAEVQPP-------PAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAE 657
AP + P PA P E PA P E P P ++ P E+
Sbjct: 584 PAPTTPKEPAPTTTKKPAPTTPKE----PAPTTPKETAP----TTPKKLTPTTPEKLAPT 635
Query: 658 VQPPPAEEAPAEVQPPPAEEAPAEVQSLPAEETPIEETLAAVHSP--PADDVPAEEASVD 715
PA P E+ P EE PA TP AA ++P PA P E A
Sbjct: 636 TPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTP---KAAAPNTPKEPAPTTPKEPAPTT 692
Query: 716 KHSP----PADLLLTEEFPIGEASAEVSPPPSEQTPEDEALVENVSTEFQSP 763
P P + T P G A + P+ TP+ A E T + P
Sbjct: 693 PKEPAPTTPKETAPTT--PKGTAPTTLK-EPAPTTPKKPAPKELAPTTTKEP 741
Score = 63.2 bits (152), Expect = 1e-09
Identities = 101/452 (22%), Positives = 166/452 (36%), Gaps = 76/452 (16%)
Query: 358 SPSEEPPAEILPPPAEKSPSVELLGEIRSPSAQ-----KAPIEVQPLPAEGAL---EEAP 409
+P+ P ++ PPP+ S +++ + RSP K IE + + E ++ +E+
Sbjct: 109 NPTSPPSSKKAPPPSGASQTIKSTTK-RSPKPPNKKKTKKVIESEEITEEHSVSENQESS 167
Query: 410 AKVEPPTVEETLADVQPLLPEEAPREEARELQLSTAMETPAEEAPTEFQSPLPKETTAEE 469
+ + T+ ++ A RE ++L++ + ++ PT PK +E
Sbjct: 168 SSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPT------PKPPVVDE 221
Query: 470 ASAEIQLLAATEPPADETPAEARSPLSEETSAEEAHAEVQSPLAEETTAEEASAEIQLLA 529
A + + D + +P +TS + + SP + TTA+ + L
Sbjct: 222 AGSGL----------DNGDFKVTTP---DTSTTQHNKVSTSP--KITTAKPINPRPSL-- 264
Query: 530 AIEAPADETPAEAQSPLSEETSAEEAPAEVQSPSAKGVSIEEAPLELQPPSGEETTAEEA 589
P +T E +++ET+ E + E+ + S E+T+A++
Sbjct: 265 ---PPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDL 321
Query: 590 SAAIQLLAATEASAE---EAPAEVQPP-PAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAE 645
+ ++LA AE + PA P P P E PA P E P + AP
Sbjct: 322 APTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKE----PASTTPKEPTPTTIKSAPTT 377
Query: 646 VQPP-----------PAEEAPAEVQPP----PAEEAPAEVQPP-----------PAEEAP 679
+ P P E AP + P P E AP + P P E AP
Sbjct: 378 PKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAP 437
Query: 680 AEVQSLPAEETPIEETLAAVHSPPADDVPAEEASVDKHSPPADLLLTEEFPIGEASAEVS 739
+ PA TP +E P P E A K P T + P A + +
Sbjct: 438 TTPKK-PAPTTP-KEPAPTTPKEPTPTTPKEPAPTTKEPAPT----TPKEPAPTAPKKPA 491
Query: 740 P-PPSEQTPEDEALVENVSTEFQSPQVAGIPA 770
P P E P +T+ SP PA
Sbjct: 492 PTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPA 523
Score = 58.2 bits (139), Expect = 3e-08
Identities = 91/418 (21%), Positives = 145/418 (34%), Gaps = 47/418 (11%)
Query: 239 TVPVVQEGSAVKKVASAEIEP-PSTEKFPA--KIQPPLVEEATAKAEPRPAEETHVQVQP 295
T P +G+A + EP P+T K PA ++ P +E T+ +PA T P
Sbjct: 704 TAPTTPKGTAPTTLK----EPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAP 759
Query: 296 STEETPDAEAATAVAENSVKVQPP-----PAEEAPLVEFPAEIQPPSAE-------ESPS 343
+T + P A + K P PA P P E+ P + + + P+
Sbjct: 760 TTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPA 819
Query: 344 VELLAEILPPSAEESPSEEPPAEILPPPAEKSPSVELLGEIRSPSAQKAPIEVQPLPAEG 403
E P + +E P+ P + P E P E+ +P+ K P + P E
Sbjct: 820 PTTPKETAPTTPKE-PAPTTPKKPAPTTPETPPPTT--SEVSTPTTTKEPTTIHKSPDES 876
Query: 404 -----------ALEEAPAKVEPPTVEETLADVQPLLPEEAPREEARELQLSTAMETPAEE 452
ALE +P + PT +T A +P + A +++ E L T ET
Sbjct: 877 TPELSAEPTPKALENSPKEPGVPTT-KTPAATKPEMTTTA-KDKTTERDLRTTPET---- 930
Query: 453 APTEFQSPLPKETTAEEASAEIQLLAATEPPADETPAEARSPLSEETSAEEAHAEVQSPL 512
T + KET + AT T + +P T A +
Sbjct: 931 --TTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTT 988
Query: 513 AEETTAEEASAEIQLLAAIEAPADETPAEAQSPLSEETSAEEAPAEVQSPS----AKGVS 568
+ T E + + A + A + A P + T A + P + P +
Sbjct: 989 KKTITTTEIMNKPEETAKPKDRATNSKATTPKP-QKPTKAPKKPTSTKKPKTMPRVRKPK 1047
Query: 569 IEEAPLELQPPSGE-ETTAEEASAAIQLLAATEASAEEAPAEVQPPPAEEAPAEVQPP 625
P ++ E T+ A A +Q + EV P + AE + P
Sbjct: 1048 TTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSEDAGGAEGETP 1105
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 120 bits (301), Expect = 5e-27
Identities = 160/672 (23%), Positives = 233/672 (34%), Gaps = 52/672 (7%)
Query: 122 PSVQLKMDRSQQTSRT-GYWTMMNIPPVEKVDKEQQTYFSESEIVVISRPDSSSTKSKED 180
PS+ D S++TS T T + +K+ T E T +K+
Sbjct: 128 PSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDL 187
Query: 181 ALKHKSSGKIFASEHPEFQPATNSNEEIGQKNISRTSFTQETKKGPPVLLEDELREEVTV 240
A + K+ A P+ + T K + T+ + P ++ T
Sbjct: 188 A----PTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTT 243
Query: 241 PVVQEGSAVKKVASAEIEP-PSTEKFPAKIQPPLVEEATAKAEPRPAEETHVQVQPSTEE 299
P + K + EP P+T K PA P T K EP P T + P+T +
Sbjct: 244 PKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTK-EPAP---TTTKSAPTTPK 299
Query: 300 TPDAEAATAVAENSVKVQPPPAEEAPLVEFPAEIQPPSAEESPSVELLAEILPPSAEESP 359
P A + K P + P P E P + E +P+ + P+A + P
Sbjct: 300 EPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTP---KEPAPTAPKKP 356
Query: 360 SEEPPAEILP-------PPAEKSPSVELLGEIRSPSAQKAPIEVQPLPAEGALEEAPAKV 412
+ P E P P K PS E + + AP + PA + AP
Sbjct: 357 APTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKE-PAPTTTKSAPTTP 415
Query: 413 EPPTVEETLADVQPLLPEE----APREEARELQLSTAMETPAEEAPTEFQSPLPKETTAE 468
+ P+ T + P P+E P++ A A TP E APT + P P TT +
Sbjct: 416 KEPS-PTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAP--TTPK 472
Query: 469 EASAEIQLLAATEPPADETPA--EARSPLSEETSAEEAHAEVQSPLAEE---TTAEEASA 523
E + A P TP E +P + E A E+ EE TT EE +
Sbjct: 473 EPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAP 532
Query: 524 EIQLLAAIEAPADETPAEAQ--SPLSEETSAEEAPAEVQSPSAKGVSIEEAPLELQPPSG 581
AA P + P + +P + + A P E + KG AP L+ P+
Sbjct: 533 TTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGT----APTTLKEPA- 587
Query: 582 EETTAEEASAAIQLLAATEASAEEAPAEVQPPPAEEAPAEVQPP-PAEEAPAEVQPPPAE 640
T + A +L T + P + A P PA P E P +
Sbjct: 588 --PTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPK 645
Query: 641 EAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQSLPAEETPIEETLAAVH 700
PA P + P P E AP + P + PA TP +ET
Sbjct: 646 GTAPTTLKEPAPTTPKK--PAPKELAPTTTKGP-----TSTTSDKPAPTTP-KETAPTTP 697
Query: 701 SPPADDVPAEEASVDKHSPPADLLLTEEFPIGEASAEVSPPPSEQTPEDEALVENVSTEF 760
PA P + A +PP + + P E TPE A + E
Sbjct: 698 KEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALE- 756
Query: 761 QSPQVAGIPAVK 772
SP+ G+P K
Sbjct: 757 NSPKEPGVPTTK 768
Score = 105 bits (261), Expect = 2e-22
Identities = 172/721 (23%), Positives = 251/721 (34%), Gaps = 99/721 (13%)
Query: 72 SLQTDTIVEEKKEVKLVEETVVPEEKSADVREAAIELPESVQDVE------IPPNIPSVQ 125
S +T V ++ V+ E T ++ S D +E E+ Q +E + P +
Sbjct: 137 SKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKET-QSIEKTSAKDLAPTSKVLA 195
Query: 126 LKMDRSQQTSRTGYWTMMNIP-------PVEKVDKEQQTYFSESEIVVISRPDSSSTKSK 178
+++ T++ T P P KE +S P ++TKS
Sbjct: 196 KPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSA 255
Query: 179 EDALKHKS--SGKIFASEHPEFQPATNSNEEIGQKNISRTSFTQE----TKKGPPVLLED 232
K + + K A P+ T + E S + +E T K P
Sbjct: 256 PTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPK 315
Query: 233 ELREEVTVPVVQEGSAVKKVASAEIEP-PSTEKFPAKIQPPLVEEATAKAEPRPAEETHV 291
E T P + K+ A EP P+T K PA P T K PA T
Sbjct: 316 E--PAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPK---EPAPTTPK 370
Query: 292 QVQPSTEETPDAEAATAVAENSVKVQPPPAEE-APLVEFPAEIQPPSAEESPSVELLAEI 350
+ P+T + P A + K P +E AP A P+ + PS E
Sbjct: 371 EPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSA----PTTPKEPSPTTTKEP 426
Query: 351 LP-------PSAEESPSEEPPAEILPP-PAEKSPSVELLGEIRSPS--AQKAPIEVQPLP 400
P P+ + P+ P E P P E +P+ +P A P E P
Sbjct: 427 APTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTT 486
Query: 401 AEGALEEAPAKVEPPTVEE----TLADVQPLLPEE----APREEARELQLSTAMETPAEE 452
+ P K+ P T E+ T ++ P PEE P E A + A TP E
Sbjct: 487 PKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEP 546
Query: 453 APTEFQSPLPKETTAEEASAEIQLLAATEPPADETPAEARSPLSEETSAEEAHAEVQSPL 512
APT + P P TT +E + A P P + P + T + A E L
Sbjct: 547 APTTPKEPAP--TTPKEPAPTTPKETAPTTPKGTAPTTLKEP-APTTPKKPAPKE----L 599
Query: 513 AEETTAEEASAEIQLLAAIEAPADETPAEAQSPLSEETSAEEAPAEVQSPSAKGVSIEEA 572
A TT E S + PA TP + +P + + A P E + KG A
Sbjct: 600 APTTTKEPTS------TTCDKPAPTTP-KGTAPTTPKEPAPTTPKEPAPTTPKGT----A 648
Query: 573 PLELQPPSGEETTAEEASAAIQLLAATEASAEEAPAEVQPPPAEEAPAEVQPPPAEEAPA 632
P L+ P A + AP E+ P + + PA P
Sbjct: 649 PTTLKEP------------------APTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPK 690
Query: 633 EVQP-PPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQSLPAEETP 691
E P P E AP P + AP + PP +EV P + P + P E TP
Sbjct: 691 ETAPTTPKEPAPT----TPKKPAPTTPETPP--PTTSEVSTPTTTKEPTTIHKSPDESTP 744
Query: 692 IEETLAAVHSPPADDVPAEEASVDKHSPPA----DLLLTEEFPIGEASAEVSPPPSEQTP 747
L+A +P A + +E V PA ++ T + E +P + P
Sbjct: 745 ---ELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAP 801
Query: 748 E 748
+
Sbjct: 802 K 802
Score = 85.1 bits (209), Expect = 2e-16
Identities = 150/604 (24%), Positives = 215/604 (35%), Gaps = 102/604 (16%)
Query: 167 ISRPDSSSTKSKEDALKHKSSGKIFASEHPEFQPATNSNEEIGQKNISRTSFTQETKKGP 226
++ PD+S+T+ + + K + + P P +++++E T T ETK+
Sbjct: 99 VTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKET--TVETKETT 156
Query: 227 PVLLEDELREEVTVPVVQEGSAVKKVASAEIEPPSTEKFPAKIQPPLVEEATAKAEPRPA 286
+ + +E +++K ++ ++ P T K AK P E T K PA
Sbjct: 157 TTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAP--TSKVLAKPTPKA--ETTTKG---PA 209
Query: 287 EETHVQVQPSTEETPDAEAATAVAENSVKVQPP-PAEEAPLVEFPAEIQPPSAEESPSVE 345
T + P+T + P + ++K P P E AP A P+ + P+
Sbjct: 210 LTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSA----PTTPKEPAPT 265
Query: 346 LLAEILPPSAEESPSEEPPAEILPPPAEKSPSVELLGEIRSPSAQKAPIEVQPLPAEGAL 405
E P + P E P P + S + +P+ K P P
Sbjct: 266 TTKEPAPTT----PKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPK------ 315
Query: 406 EEAPAKVEPPTVEETLADVQPLLPEEAPREEARELQLSTAMETPAEEAPTEFQSPLPKET 465
E AP + PT P P+E P +E A TP E APT + P P T
Sbjct: 316 EPAPTTPKEPT---------PTTPKE-PAPTTKE----PAPTTPKEPAPTAPKKPAP--T 359
Query: 466 TAEEASAEIQLLAATEPPADETPAEARSPLSEETSAEEAHAEVQSPLAEETTAEEASAEI 525
T +E A P + P + P S T E A +S A TT E A
Sbjct: 360 TPKEP--------APTTPKEPAPTTTKEP-SPTTPKEPAPTTTKS--APTTTKEPAPTTT 408
Query: 526 QLLAAIEAPADETPAEAQSPLSEETSAEEAPAEVQSPSAKGVSIEEAPLELQPPSGEETT 585
+ A TP E S T+ E AP + P AP + P+ TT
Sbjct: 409 K-------SAPTTPKEP----SPTTTKEPAPTTPKEP---------APTTPKKPA--PTT 446
Query: 586 AEEASAAIQLLAATEASAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAE 645
+E A E AP + P A P E PA P E P P +
Sbjct: 447 PKEP--------APTTPKEPAPTTTKKP-APTTPKE----PAPTTPKETAP----TTPKK 489
Query: 646 VQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQSLPAEETPIEETLAAVHSP--P 703
+ P E+ PA P E+ P EE PA TP AA ++P P
Sbjct: 490 LTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTP---KAAAPNTPKEP 546
Query: 704 ADDVPAEEASVDKHSP----PADLLLTEEFPIGEASAEVSPPPSEQTPEDEALVENVSTE 759
A P E A P P + T P G A + P+ TP+ A E T
Sbjct: 547 APTTPKEPAPTTPKEPAPTTPKETAPTT--PKGTAPTTLK-EPAPTTPKKPAPKELAPTT 603
Query: 760 FQSP 763
+ P
Sbjct: 604 TKEP 607
Score = 58.2 bits (139), Expect = 3e-08
Identities = 91/418 (21%), Positives = 145/418 (34%), Gaps = 47/418 (11%)
Query: 239 TVPVVQEGSAVKKVASAEIEP-PSTEKFPA--KIQPPLVEEATAKAEPRPAEETHVQVQP 295
T P +G+A + EP P+T K PA ++ P +E T+ +PA T P
Sbjct: 570 TAPTTPKGTAPTTLK----EPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAP 625
Query: 296 STEETPDAEAATAVAENSVKVQPP-----PAEEAPLVEFPAEIQPPSAE-------ESPS 343
+T + P A + K P PA P P E+ P + + + P+
Sbjct: 626 TTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPA 685
Query: 344 VELLAEILPPSAEESPSEEPPAEILPPPAEKSPSVELLGEIRSPSAQKAPIEVQPLPAEG 403
E P + +E P+ P + P E P E+ +P+ K P + P E
Sbjct: 686 PTTPKETAPTTPKE-PAPTTPKKPAPTTPETPPPTT--SEVSTPTTTKEPTTIHKSPDES 742
Query: 404 -----------ALEEAPAKVEPPTVEETLADVQPLLPEEAPREEARELQLSTAMETPAEE 452
ALE +P + PT +T A +P + A +++ E L T ET
Sbjct: 743 TPELSAEPTPKALENSPKEPGVPTT-KTPAATKPEMTTTA-KDKTTERDLRTTPET---- 796
Query: 453 APTEFQSPLPKETTAEEASAEIQLLAATEPPADETPAEARSPLSEETSAEEAHAEVQSPL 512
T + KET + AT T + +P T A +
Sbjct: 797 --TTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTT 854
Query: 513 AEETTAEEASAEIQLLAAIEAPADETPAEAQSPLSEETSAEEAPAEVQSPS----AKGVS 568
+ T E + + A + A + A P + T A + P + P +
Sbjct: 855 KKTITTTEIMNKPEETAKPKDRATNSKATTPKP-QKPTKAPKKPTSTKKPKTMPRVRKPK 913
Query: 569 IEEAPLELQPPSGE-ETTAEEASAAIQLLAATEASAEEAPAEVQPPPAEEAPAEVQPP 625
P ++ E T+ A A +Q + EV P + AE + P
Sbjct: 914 TTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSEDAGGAEGETP 971
Score = 52.8 bits (125), Expect = 1e-06
Identities = 81/344 (23%), Positives = 120/344 (34%), Gaps = 61/344 (17%)
Query: 458 QSPLPKETTAEEASAEIQLLAATEPPADETPAEARSPLSEETSAEEAHAEVQSPLAEETT 517
+ P PK +EA + + D + +P +TS + + SP + TT
Sbjct: 76 KKPTPKPPVVDEAGSGL----------DNGDFKVTTP---DTSTTQHNKVSTSP--KITT 120
Query: 518 AEEASAEIQLLAAIEAPADETPAEAQSPLSEETSAEEAPAEVQSPSAKGVSIEEAPLELQ 577
A+ + L P +T E +++ET+ E + E+ +
Sbjct: 121 AKPINPRPSL-----PPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKE 175
Query: 578 PPSGEETTAEEASAAIQLLAATEASAE---EAPAEVQPP-PAEEAPAEVQPPPAEEAPAE 633
S E+T+A++ + ++LA AE + PA P P P E PA P E
Sbjct: 176 TQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKE----PASTTPKE 231
Query: 634 VQPPPAEEAPAEVQPP-----------PAEEAPAEVQPP----PAEEAPAEVQPP----- 673
P + AP + P P E AP + P P E AP + P
Sbjct: 232 PTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTT 291
Query: 674 ------PAEEAPAEVQSLPAEETPIEETLAAVHSPPADDVPAEEASVDKHSPPADLLLTE 727
P E AP + PA TP +E P P E A K P T
Sbjct: 292 KSAPTTPKEPAPTTPKK-PAPTTP-KEPAPTTPKEPTPTTPKEPAPTTKEPAPT----TP 345
Query: 728 EFPIGEASAEVSP-PPSEQTPEDEALVENVSTEFQSPQVAGIPA 770
+ P A + +P P E P +T+ SP PA
Sbjct: 346 KEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPA 389
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 120 bits (301), Expect = 5e-27
Identities = 160/672 (23%), Positives = 233/672 (34%), Gaps = 52/672 (7%)
Query: 122 PSVQLKMDRSQQTSRT-GYWTMMNIPPVEKVDKEQQTYFSESEIVVISRPDSSSTKSKED 180
PS+ D S++TS T T + +K+ T E T +K+
Sbjct: 169 PSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDL 228
Query: 181 ALKHKSSGKIFASEHPEFQPATNSNEEIGQKNISRTSFTQETKKGPPVLLEDELREEVTV 240
A + K+ A P+ + T K + T+ + P ++ T
Sbjct: 229 A----PTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTT 284
Query: 241 PVVQEGSAVKKVASAEIEP-PSTEKFPAKIQPPLVEEATAKAEPRPAEETHVQVQPSTEE 299
P + K + EP P+T K PA P T K EP P T + P+T +
Sbjct: 285 PKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTK-EPAP---TTTKSAPTTPK 340
Query: 300 TPDAEAATAVAENSVKVQPPPAEEAPLVEFPAEIQPPSAEESPSVELLAEILPPSAEESP 359
P A + K P + P P E P + E +P+ + P+A + P
Sbjct: 341 EPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTP---KEPAPTAPKKP 397
Query: 360 SEEPPAEILP-------PPAEKSPSVELLGEIRSPSAQKAPIEVQPLPAEGALEEAPAKV 412
+ P E P P K PS E + + AP + PA + AP
Sbjct: 398 APTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKE-PAPTTTKSAPTTP 456
Query: 413 EPPTVEETLADVQPLLPEE----APREEARELQLSTAMETPAEEAPTEFQSPLPKETTAE 468
+ P+ T + P P+E P++ A A TP E APT + P P TT +
Sbjct: 457 KEPS-PTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAP--TTPK 513
Query: 469 EASAEIQLLAATEPPADETPA--EARSPLSEETSAEEAHAEVQSPLAEE---TTAEEASA 523
E + A P TP E +P + E A E+ EE TT EE +
Sbjct: 514 EPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAP 573
Query: 524 EIQLLAAIEAPADETPAEAQ--SPLSEETSAEEAPAEVQSPSAKGVSIEEAPLELQPPSG 581
AA P + P + +P + + A P E + KG AP L+ P+
Sbjct: 574 TTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGT----APTTLKEPA- 628
Query: 582 EETTAEEASAAIQLLAATEASAEEAPAEVQPPPAEEAPAEVQPP-PAEEAPAEVQPPPAE 640
T + A +L T + P + A P PA P E P +
Sbjct: 629 --PTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPK 686
Query: 641 EAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQSLPAEETPIEETLAAVH 700
PA P + P P E AP + P + PA TP +ET
Sbjct: 687 GTAPTTLKEPAPTTPKK--PAPKELAPTTTKGP-----TSTTSDKPAPTTP-KETAPTTP 738
Query: 701 SPPADDVPAEEASVDKHSPPADLLLTEEFPIGEASAEVSPPPSEQTPEDEALVENVSTEF 760
PA P + A +PP + + P E TPE A + E
Sbjct: 739 KEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALE- 797
Query: 761 QSPQVAGIPAVK 772
SP+ G+P K
Sbjct: 798 NSPKEPGVPTTK 809
Score = 105 bits (261), Expect = 2e-22
Identities = 172/721 (23%), Positives = 251/721 (34%), Gaps = 99/721 (13%)
Query: 72 SLQTDTIVEEKKEVKLVEETVVPEEKSADVREAAIELPESVQDVE------IPPNIPSVQ 125
S +T V ++ V+ E T ++ S D +E E+ Q +E + P +
Sbjct: 178 SKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKET-QSIEKTSAKDLAPTSKVLA 236
Query: 126 LKMDRSQQTSRTGYWTMMNIP-------PVEKVDKEQQTYFSESEIVVISRPDSSSTKSK 178
+++ T++ T P P KE +S P ++TKS
Sbjct: 237 KPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSA 296
Query: 179 EDALKHKS--SGKIFASEHPEFQPATNSNEEIGQKNISRTSFTQE----TKKGPPVLLED 232
K + + K A P+ T + E S + +E T K P
Sbjct: 297 PTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPK 356
Query: 233 ELREEVTVPVVQEGSAVKKVASAEIEP-PSTEKFPAKIQPPLVEEATAKAEPRPAEETHV 291
E T P + K+ A EP P+T K PA P T K PA T
Sbjct: 357 E--PAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPK---EPAPTTPK 411
Query: 292 QVQPSTEETPDAEAATAVAENSVKVQPPPAEE-APLVEFPAEIQPPSAEESPSVELLAEI 350
+ P+T + P A + K P +E AP A P+ + PS E
Sbjct: 412 EPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSA----PTTPKEPSPTTTKEP 467
Query: 351 LP-------PSAEESPSEEPPAEILPP-PAEKSPSVELLGEIRSPS--AQKAPIEVQPLP 400
P P+ + P+ P E P P E +P+ +P A P E P
Sbjct: 468 APTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTT 527
Query: 401 AEGALEEAPAKVEPPTVEE----TLADVQPLLPEE----APREEARELQLSTAMETPAEE 452
+ P K+ P T E+ T ++ P PEE P E A + A TP E
Sbjct: 528 PKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEP 587
Query: 453 APTEFQSPLPKETTAEEASAEIQLLAATEPPADETPAEARSPLSEETSAEEAHAEVQSPL 512
APT + P P TT +E + A P P + P + T + A E L
Sbjct: 588 APTTPKEPAP--TTPKEPAPTTPKETAPTTPKGTAPTTLKEP-APTTPKKPAPKE----L 640
Query: 513 AEETTAEEASAEIQLLAAIEAPADETPAEAQSPLSEETSAEEAPAEVQSPSAKGVSIEEA 572
A TT E S + PA TP + +P + + A P E + KG A
Sbjct: 641 APTTTKEPTS------TTCDKPAPTTP-KGTAPTTPKEPAPTTPKEPAPTTPKGT----A 689
Query: 573 PLELQPPSGEETTAEEASAAIQLLAATEASAEEAPAEVQPPPAEEAPAEVQPPPAEEAPA 632
P L+ P A + AP E+ P + + PA P
Sbjct: 690 PTTLKEP------------------APTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPK 731
Query: 633 EVQP-PPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQSLPAEETP 691
E P P E AP P + AP + PP +EV P + P + P E TP
Sbjct: 732 ETAPTTPKEPAPT----TPKKPAPTTPETPP--PTTSEVSTPTTTKEPTTIHKSPDESTP 785
Query: 692 IEETLAAVHSPPADDVPAEEASVDKHSPPA----DLLLTEEFPIGEASAEVSPPPSEQTP 747
L+A +P A + +E V PA ++ T + E +P + P
Sbjct: 786 ---ELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAP 842
Query: 748 E 748
+
Sbjct: 843 K 843
Score = 85.1 bits (209), Expect = 2e-16
Identities = 150/604 (24%), Positives = 215/604 (35%), Gaps = 102/604 (16%)
Query: 167 ISRPDSSSTKSKEDALKHKSSGKIFASEHPEFQPATNSNEEIGQKNISRTSFTQETKKGP 226
++ PD+S+T+ + + K + + P P +++++E T T ETK+
Sbjct: 140 VTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKET--TVETKETT 197
Query: 227 PVLLEDELREEVTVPVVQEGSAVKKVASAEIEPPSTEKFPAKIQPPLVEEATAKAEPRPA 286
+ + +E +++K ++ ++ P T K AK P E T K PA
Sbjct: 198 TTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAP--TSKVLAKPTPKA--ETTTKG---PA 250
Query: 287 EETHVQVQPSTEETPDAEAATAVAENSVKVQPP-PAEEAPLVEFPAEIQPPSAEESPSVE 345
T + P+T + P + ++K P P E AP A P+ + P+
Sbjct: 251 LTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSA----PTTPKEPAPT 306
Query: 346 LLAEILPPSAEESPSEEPPAEILPPPAEKSPSVELLGEIRSPSAQKAPIEVQPLPAEGAL 405
E P + P E P P + S + +P+ K P P
Sbjct: 307 TTKEPAPTT----PKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPK------ 356
Query: 406 EEAPAKVEPPTVEETLADVQPLLPEEAPREEARELQLSTAMETPAEEAPTEFQSPLPKET 465
E AP + PT P P+E P +E A TP E APT + P P T
Sbjct: 357 EPAPTTPKEPT---------PTTPKE-PAPTTKE----PAPTTPKEPAPTAPKKPAP--T 400
Query: 466 TAEEASAEIQLLAATEPPADETPAEARSPLSEETSAEEAHAEVQSPLAEETTAEEASAEI 525
T +E A P + P + P S T E A +S A TT E A
Sbjct: 401 TPKEP--------APTTPKEPAPTTTKEP-SPTTPKEPAPTTTKS--APTTTKEPAPTTT 449
Query: 526 QLLAAIEAPADETPAEAQSPLSEETSAEEAPAEVQSPSAKGVSIEEAPLELQPPSGEETT 585
+ A TP E S T+ E AP + P AP + P+ TT
Sbjct: 450 K-------SAPTTPKEP----SPTTTKEPAPTTPKEP---------APTTPKKPA--PTT 487
Query: 586 AEEASAAIQLLAATEASAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAE 645
+E A E AP + P A P E PA P E P P +
Sbjct: 488 PKEP--------APTTPKEPAPTTTKKP-APTTPKE----PAPTTPKETAP----TTPKK 530
Query: 646 VQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQSLPAEETPIEETLAAVHSP--P 703
+ P E+ PA P E+ P EE PA TP AA ++P P
Sbjct: 531 LTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTP---KAAAPNTPKEP 587
Query: 704 ADDVPAEEASVDKHSP----PADLLLTEEFPIGEASAEVSPPPSEQTPEDEALVENVSTE 759
A P E A P P + T P G A + P+ TP+ A E T
Sbjct: 588 APTTPKEPAPTTPKEPAPTTPKETAPTT--PKGTAPTTLK-EPAPTTPKKPAPKELAPTT 644
Query: 760 FQSP 763
+ P
Sbjct: 645 TKEP 648
Score = 58.2 bits (139), Expect = 3e-08
Identities = 91/418 (21%), Positives = 145/418 (34%), Gaps = 47/418 (11%)
Query: 239 TVPVVQEGSAVKKVASAEIEP-PSTEKFPA--KIQPPLVEEATAKAEPRPAEETHVQVQP 295
T P +G+A + EP P+T K PA ++ P +E T+ +PA T P
Sbjct: 611 TAPTTPKGTAPTTLK----EPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAP 666
Query: 296 STEETPDAEAATAVAENSVKVQPP-----PAEEAPLVEFPAEIQPPSAE-------ESPS 343
+T + P A + K P PA P P E+ P + + + P+
Sbjct: 667 TTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPA 726
Query: 344 VELLAEILPPSAEESPSEEPPAEILPPPAEKSPSVELLGEIRSPSAQKAPIEVQPLPAEG 403
E P + +E P+ P + P E P E+ +P+ K P + P E
Sbjct: 727 PTTPKETAPTTPKE-PAPTTPKKPAPTTPETPPPTT--SEVSTPTTTKEPTTIHKSPDES 783
Query: 404 -----------ALEEAPAKVEPPTVEETLADVQPLLPEEAPREEARELQLSTAMETPAEE 452
ALE +P + PT +T A +P + A +++ E L T ET
Sbjct: 784 TPELSAEPTPKALENSPKEPGVPTT-KTPAATKPEMTTTA-KDKTTERDLRTTPET---- 837
Query: 453 APTEFQSPLPKETTAEEASAEIQLLAATEPPADETPAEARSPLSEETSAEEAHAEVQSPL 512
T + KET + AT T + +P T A +
Sbjct: 838 --TTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTT 895
Query: 513 AEETTAEEASAEIQLLAAIEAPADETPAEAQSPLSEETSAEEAPAEVQSPS----AKGVS 568
+ T E + + A + A + A P + T A + P + P +
Sbjct: 896 KKTITTTEIMNKPEETAKPKDRATNSKATTPKP-QKPTKAPKKPTSTKKPKTMPRVRKPK 954
Query: 569 IEEAPLELQPPSGE-ETTAEEASAAIQLLAATEASAEEAPAEVQPPPAEEAPAEVQPP 625
P ++ E T+ A A +Q + EV P + AE + P
Sbjct: 955 TTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSEDAGGAEGETP 1012
Score = 52.8 bits (125), Expect = 1e-06
Identities = 81/344 (23%), Positives = 120/344 (34%), Gaps = 61/344 (17%)
Query: 458 QSPLPKETTAEEASAEIQLLAATEPPADETPAEARSPLSEETSAEEAHAEVQSPLAEETT 517
+ P PK +EA + + D + +P +TS + + SP + TT
Sbjct: 117 KKPTPKPPVVDEAGSGL----------DNGDFKVTTP---DTSTTQHNKVSTSP--KITT 161
Query: 518 AEEASAEIQLLAAIEAPADETPAEAQSPLSEETSAEEAPAEVQSPSAKGVSIEEAPLELQ 577
A+ + L P +T E +++ET+ E + E+ +
Sbjct: 162 AKPINPRPSL-----PPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKE 216
Query: 578 PPSGEETTAEEASAAIQLLAATEASAE---EAPAEVQPP-PAEEAPAEVQPPPAEEAPAE 633
S E+T+A++ + ++LA AE + PA P P P E PA P E
Sbjct: 217 TQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKE----PASTTPKE 272
Query: 634 VQPPPAEEAPAEVQPP-----------PAEEAPAEVQPP----PAEEAPAEVQPP----- 673
P + AP + P P E AP + P P E AP + P
Sbjct: 273 PTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTT 332
Query: 674 ------PAEEAPAEVQSLPAEETPIEETLAAVHSPPADDVPAEEASVDKHSPPADLLLTE 727
P E AP + PA TP +E P P E A K P T
Sbjct: 333 KSAPTTPKEPAPTTPKK-PAPTTP-KEPAPTTPKEPTPTTPKEPAPTTKEPAPT----TP 386
Query: 728 EFPIGEASAEVSP-PPSEQTPEDEALVENVSTEFQSPQVAGIPA 770
+ P A + +P P E P +T+ SP PA
Sbjct: 387 KEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPA 430
>gi|149773456 hypothetical protein LOC643314 [Homo sapiens]
Length = 1427
Score = 107 bits (267), Expect = 5e-23
Identities = 151/552 (27%), Positives = 203/552 (36%), Gaps = 71/552 (12%)
Query: 250 KKVASA-EIEPPSTEKFPAKIQP------PLVEEATAKAEPRPAEETHVQVQPSTEETPD 302
K+V A EP E P +P P V++A A P P E T + P+ E T
Sbjct: 812 KQVTKAGNTEPVLEEWIPVLQRPSRTAAVPTVKDALDAALPSPEEGTSIAAVPAPEGTAV 871
Query: 303 AEAATAVAENSVKVQPPPAEEAPLVEFPAEIQPPSAEESPSVELLAEILPPSAEESPSEE 362
A + V A L E SA E +V + +P +
Sbjct: 872 VAALVPFPHEDILV----ASIVSLEEEDVTAAAVSAPERATVPAVTVSVPEGTAAVAAVS 927
Query: 363 PPAEILPPPAEKSPSVELLGEIRSPSAQKAPIEVQ-PLPAEGALEEAPAKVEPPTVEETL 421
P E P A + + E + + S + A + + P+ E E P V P T
Sbjct: 928 SPEETAPAVAA-AITQEGMSAVAGFSPEWAALAITVPITEEDGTPEGP--VTPATTVHA- 983
Query: 422 ADVQPLLPEE----APREEARELQLSTAMETPAEEAPTEFQSPLPKETTAEEASAEIQLL 477
PEE A R E S A P E PT SP T EE ++
Sbjct: 984 -------PEEPDTAAVRVSTPEEPASPAAAVPTPEEPT---SPAAAVPTPEEPTSPA--- 1030
Query: 478 AATEPPADETPAEARSPLSEETSAEEAHAEVQSPLAEETTAEEASAEIQLLAAIEAPADE 537
AA PP + T A P EE + SP A T EE ++ AA+ P +
Sbjct: 1031 AAVPPPEEPTSPAAAVPTPEEPT---------SPAAAVPTPEEPTSPA---AAVPTPEEP 1078
Query: 538 TPAEAQSPLSEETSAEEAPAEVQSPSAKGVSIEEAPLELQPPSGEETTAEEASAAIQLLA 597
T A P EE ++ A + P E P+ T EE ++ +
Sbjct: 1079 TSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVP 1138
Query: 598 ATEASAEEAPAEVQPPPAEEAPAEVQPPPAEEA--PAEVQPPPAEEAPAEVQPPPAEE-- 653
E A APA P P E A A V P EE+ PA P PAE A EE
Sbjct: 1139 TPEEPAFPAPAV--PTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPT 1196
Query: 654 APAEVQPPPA------EEAPAEVQPPPAEEAPAEVQSLPAEETPIEETLAAVHSPPADDV 707
+PA P PA EE + P E PA + + A P E T A P ++
Sbjct: 1197 SPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAA--AVSNPEEPTSPAAAVPTLEEP 1254
Query: 708 PAEEASV---DKHSPPADLLLTEEFPIGEASA------EVSPPPSEQTPEDEALVENVST 758
+ A+V ++ S PA + T E P A+A SP + TPE A+ +
Sbjct: 1255 TSSAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEPASPAAAVPTPEVAAI---PAA 1311
Query: 759 EFQSPQVAGIPA 770
+P+V IPA
Sbjct: 1312 SVPTPEVPAIPA 1323
Score = 103 bits (258), Expect = 5e-22
Identities = 153/602 (25%), Positives = 220/602 (36%), Gaps = 62/602 (10%)
Query: 163 EIVVISRPDSSSTKSKEDALKHKSSGKIFASEHPEFQPATNSNEE-IGQKNISRTSFTQE 221
E V ++P+ + S+ ++ + S F + PE Q N E + ++ I
Sbjct: 778 ETVNDTKPELNVASSEGGEMERRDSDS-FLNIFPEKQVTKAGNTEPVLEEWIPVLQRPSR 836
Query: 222 TKKGPPVLLEDELREEVTVPVVQEGSAVKKVASAE--------IEPPSTEKFPAKIQPPL 273
T P V +D L + +P +EG+++ V + E + P + A I
Sbjct: 837 TAAVPTV--KDAL--DAALPSPEEGTSIAAVPAPEGTAVVAALVPFPHEDILVASIVSLE 892
Query: 274 VEEATAKAEPRPAEETHVQVQPSTEETPDAEAATAVAENSVKVQPPPAEEAPLVEFPAEI 333
E+ TA A P T V T P+ AA A + P E AP V
Sbjct: 893 EEDVTAAAVSAPERAT---VPAVTVSVPEGTAAVAAVSS-------PEETAPAVAAAITQ 942
Query: 334 QPPSAEE--SPSVELLAEILPPSAEESPSEEPPAEILPPPAEKSPSVELLGEIRSPSAQK 391
+ SA SP LA +P + E+ E P A + P + + +P
Sbjct: 943 EGMSAVAGFSPEWAALAITVPITEEDGTPEGPVTPATTVHAPEEPDTAAV-RVSTPEEPA 1001
Query: 392 APIEVQPLPAEGALEEAPAKVEPPTVEETLADVQPLLPEEAPREEARELQLSTAMETPAE 451
+P P P E A PT EE + + P E P A A+ TP E
Sbjct: 1002 SPAAAVPTPEEPTSPAAAV----PTPEEPTSPAAAVPPPEEPTSPA------AAVPTPEE 1051
Query: 452 EAPTEFQSPLPKETTAEEASAEIQLLAATEPPADETPAEARSPLSEETSAEEAHAEVQSP 511
P P+E T+ A+ + A TP E SP + + EE SP
Sbjct: 1052 PTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEP----TSP 1107
Query: 512 LAEETTAEEASAEIQLLAAIEAPADETPAEAQSPLSEETS--AEEAPAEVQSPSAKGVSI 569
A T EE ++ AA+ P + A P EE + A P +S SA V++
Sbjct: 1108 AAAVPTPEEPASPA---AAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASA-AVAV 1163
Query: 570 EEAPLELQPPSGEETTAEEASAAIQLLAATEASAEEAPAEVQPPPAEEAPAEVQPPPAEE 629
P + T AE AS A + AT A V P A A E PA
Sbjct: 1164 PTPEESASPAAAVPTPAESASFAA--VVATLEEPTSPAASVPTPAAMVATLEEFTSPAAS 1221
Query: 630 APAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQSLPAEE 689
P +P A + + P + A P A A + P EE + S+P E
Sbjct: 1222 VPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTP---EELSSPAASVPTPE 1278
Query: 690 TPIEETLAAVH----SPPADDVPAEEASVDKHSPPADLLLTEEFPIGEASAEVSPPPSEQ 745
P A + + PA VP E + + PA + T E P A+A PP E
Sbjct: 1279 EPASPAAAVSNLEEPASPAAAVPTPEVA----AIPAASVPTPEVPAIPAAA--VPPMEEV 1332
Query: 746 TP 747
+P
Sbjct: 1333 SP 1334
Score = 103 bits (257), Expect = 7e-22
Identities = 159/626 (25%), Positives = 224/626 (35%), Gaps = 84/626 (13%)
Query: 110 ESVQDVEIPPNIPSVQLKMDRSQQTSRTGYWTMMNIPPVEKVDKEQQTY-FSESEIVVIS 168
E+V D + P + + + R + +NI P ++V K T E I V+
Sbjct: 778 ETVNDTK-----PELNVASSEGGEMERRDSDSFLNIFPEKQVTKAGNTEPVLEEWIPVLQ 832
Query: 169 RPD-SSSTKSKEDAL-----KHKSSGKIFASEHPEFQPATNSNEEIGQKNI---SRTSFT 219
RP +++ + +DAL + I A PE + ++I S S
Sbjct: 833 RPSRTAAVPTVKDALDAALPSPEEGTSIAAVPAPEGTAVVAALVPFPHEDILVASIVSLE 892
Query: 220 QETKKGPPVLLEDELR-EEVTVPVVQEGSAVKKVASAEIEPP-----------------S 261
+E V + VTV V + +AV V+S E P S
Sbjct: 893 EEDVTAAAVSAPERATVPAVTVSVPEGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGFS 952
Query: 262 TEKFPAKIQPPLVEE-ATAKAEPRPAEETHVQVQPSTEETPDAEAATAVAENSVKVQPP- 319
E I P+ EE T + PA H +P T +V+V P
Sbjct: 953 PEWAALAITVPITEEDGTPEGPVTPATTVHAPEEPDTA--------------AVRVSTPE 998
Query: 320 -PAEEAPLVEFPAEIQPPSAEESPSVELLAEILPPSAEESPSEEP--PAEILPPPAEKSP 376
PA A V P E P+A +V E P+A P EEP PA +P P E +
Sbjct: 999 EPASPAAAVPTPEEPTSPAA----AVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTS 1054
Query: 377 SVELLGEIRSPSAQKAPIEVQPLPAEGALEEAPAKVEPPTVEETLADVQPLLPEEAPREE 436
+ +P +P P P E +PA P E T PEE
Sbjct: 1055 PA---AAVPTPEEPTSPAAAVPTPEEPT---SPAAAVPTPEEPTSPAAAVPTPEEPTSPA 1108
Query: 437 ARELQLSTAMETPAEEAPTEFQSPLPKETTAEEASAEIQLLAATEPPADETPAEARSPLS 496
A A+ TP E A P P+E + A+ A PA TP E+ S
Sbjct: 1109 A-------AVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAV 1161
Query: 497 EETSAEEAHAEVQSPLAEETTAEEASAEIQLLAAIEAPADE-----TPAEAQSPLSEETS 551
+ EE+ SP A T E+++ ++A +E P TPA + L E TS
Sbjct: 1162 AVPTPEES----ASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVATLEEFTS 1217
Query: 552 AEEAPAEVQSPSAKGVSIEEAPLELQPPSGEETTAEEASAAIQLLAATEASAEEAPAEVQ 611
+ + P++ ++ P + T E S+A +L E S+ A
Sbjct: 1218 PAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSPAASVPTP 1277
Query: 612 PPPAEEAPAEVQ-PPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEV 670
PA A A PA A A P A A V P PA PP E +P V
Sbjct: 1278 EEPASPAAAVSNLEEPASPAAAVPTPEVAAIPAASVPTPEVPAIPAAAVPPMEEVSPIGV 1337
Query: 671 QPPPAEEAPAEVQSLPAEE--TPIEE 694
P A S+P E TP+ E
Sbjct: 1338 ---PFLGVSAHTDSVPISEEGTPVLE 1360
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 100 bits (249), Expect = 6e-21
Identities = 159/589 (26%), Positives = 219/589 (37%), Gaps = 93/589 (15%)
Query: 193 SEHPEFQPATNSNEEIGQKNISRTSFTQETKKGPPVLLEDELREEVTVPVVQEGSAVKKV 252
S PE PA+ E + ++SR +E+ PP EE + E S +
Sbjct: 468 SPPPEELPASPLPEAL---HLSRP--LEESPLSPPP-------EESPLSPPPESSPFSPL 515
Query: 253 ASAEIEPPSTEKFPAKIQPPLVEEATAKAEPRPAEETHVQVQPSTEET-PDAEAATAVAE 311
+ + PP ++ PL A P EE+ + P T P EA+
Sbjct: 516 EESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPP 575
Query: 312 NSVKVQPPPAEEAPLVEFP--AEIQPPSAEESPSVELLAEILPPSAEESPSEEPP-AEIL 368
PP EE+P+ P + + PP EESP L P EESP PP A L
Sbjct: 576 PEESPMSPPPEESPMSPPPEASRLFPPF-EESP--------LSPPPEESPLSPPPEASRL 626
Query: 369 PPPAEKSPSVELLGEIRSPSAQKAPIEVQPLPAEGALEEAP--AKVEPPTVEETLADVQP 426
PP E SP SP +++P+ P P L P +++ PP E L+
Sbjct: 627 SPPPEDSPM--------SPPPEESPMS--PPPEVSRLSPLPVVSRLSPPPEESPLSPP-- 674
Query: 427 LLPEEAPREEARELQLSTAMETPAEEAPTEFQSPLPKETTAEEASAE-IQLLAATEPPAD 485
PEE+P E ++ + P E++PT SP P+++ A + + L E P
Sbjct: 675 --PEESPTSPPPE---ASRLSPPPEDSPT---SPPPEDSPASPPPEDSLMSLPLEESPLL 726
Query: 486 ETPAEAR-SPLSE----ETSAEEAHAEVQSPLAEETTAEEASAEIQLLAAIEAPA-DETP 539
P E + P SE EE H SP EE + E L E P P
Sbjct: 727 PLPEEPQLCPRSEGPHLSPRPEEPHL---SPRPEEPHLSPQAEEPHLSPQPEEPCLCAVP 783
Query: 540 AEAQ-SPLSEETSAEEAPAEVQ-SPSAKGVSIEEAPLE-LQPPSGEETTAEEASAAIQLL 596
E SP +E P E+ SP + + P E P EE+ S L
Sbjct: 784 EEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLS 843
Query: 597 AATEASAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPA 656
E S E++ PP P + PP E Q P EE P + PPP E + +
Sbjct: 844 PRPEES--HLSPELEKPPLSPRP---EKPPEEPG----QCPAPEELP--LFPPPGEPSLS 892
Query: 657 EVQPPPAEEAPAEVQPPPAEEAPAEVQSLPAEETPIEETLAAVHSPPADDVPAEEASVDK 716
+ PA P E PP P E+ P+ E + L PP P +
Sbjct: 893 PLLGEPALSEPGE---PPLSPLPEELPLSPSGEPSLSPQL----MPPDPLPPPLSPIITA 945
Query: 717 HSPPADLLLTE-EFPIGE--------------ASAEVSPPPSEQTPEDE 750
+PPA L E E+P G +SPPP + E
Sbjct: 946 AAPPALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPE 994
Score = 98.2 bits (243), Expect = 3e-20
Identities = 127/488 (26%), Positives = 178/488 (36%), Gaps = 44/488 (9%)
Query: 275 EEATAKAEPRPAEETHVQVQPSTEETPDAEAATAVAENSVKVQPPPAEEAPLVEFP--AE 332
E + E +P + VQ++P E + E + PPP EE+P P +
Sbjct: 408 EPGPLQCEAKPLGKAGVQLEPQLEAPLNEEMPLLPPPEESPLSPPP-EESPTSPPPEASR 466
Query: 333 IQPPSAEESPSVELLAEILPPSAEESPSEEPPAEI-LPPPAEKSPSVELLGEIRSPSAQK 391
+ PP E S A L EESP PP E L PP E SP L SP +
Sbjct: 467 LSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEES 526
Query: 392 APIEVQPLPAEGALEEAPAKVEPPTVEETLADVQPLLPEEAPREEARELQLSTAMETPAE 451
P P E +P + PP E L+ LP P E +R + P E
Sbjct: 527 PPSPALETPLSPPPEASP--LSPPFEESPLSPPPEELPTSPPPEASR-------LSPPPE 577
Query: 452 EAPTEFQSPLPKETTAEEASAEIQLLAATEPPADETPAE---ARSPLSEETSAEEAHAEV 508
E+P SP P+E+ +L PP +E+P SPLS A
Sbjct: 578 ESP---MSPPPEESPMSPPPEASRLF----PPFEESPLSPPPEESPLSPPPEASRLSPPP 630
Query: 509 Q-SPLA--EETTAEEASAEIQLLAAIEAPADETPAEAQSPLSEETSAEEAPAEVQSPSAK 565
+ SP++ E + E+ L+ + + +P +SPLS EE+P P A
Sbjct: 631 EDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLS--PPPEESPTS-PPPEAS 687
Query: 566 GVSIEEAPLELQPPSGEETTAEEASAAIQLLAATEASAEEAPAEVQPPPAEEAPAEVQPP 625
+S PP + + ++ L E+ P E Q P E P + P
Sbjct: 688 RLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGP-HLSPR 746
Query: 626 PAEE--APAEVQP---PPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPA 680
P E +P +P P AEE QP E P P + + P P
Sbjct: 747 PEEPHLSPRPEEPHLSPQAEEPHLSPQP----EEPCLCAVPEEPHLSPQAEGPHLSPQPE 802
Query: 681 EVQSLPAEETPIEETLAAVHSPPADDVPAEEASVDKHSPPADLLLTEEFPIGEASAEVSP 740
E+ P E P L+ V P EE+ + S + L+ S E+
Sbjct: 803 ELHLSPQTEEP---HLSPVPEEPCLSPQPEESHLSPQS--EEPCLSPRPEESHLSPELEK 857
Query: 741 PPSEQTPE 748
PP PE
Sbjct: 858 PPLSPRPE 865
Score = 83.2 bits (204), Expect = 9e-16
Identities = 90/319 (28%), Positives = 120/319 (37%), Gaps = 49/319 (15%)
Query: 455 TEFQSPLPKETTAEEASAEIQLLAATEPPADETPAEARSPLSEETSAE-------EAHAE 507
+ F P P +T +E A T + + P + A+ + +
Sbjct: 370 SRFSPPEPGDTPTDEPDALYVACQGQPKGGHVTSMQPKEPGPLQCEAKPLGKAGVQLEPQ 429
Query: 508 VQSPLAEETTAEEASAEIQLLAAIEAPADETPAEAQ--SPLSEETSAEEAPAEVQSPSAK 565
+++PL EE E L E P EA SP EE A P +
Sbjct: 430 LEAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRP- 488
Query: 566 GVSIEEAPLELQPPSGEETTAEEASAAIQLLAATEASAEEAPAEVQPPPAEEAPAEVQP- 624
+EE+PL P + E+S L E S P E P PA E P P
Sbjct: 489 ---LEESPLSPPPEESPLSPPPESSPFSPL----EESPLSPPEESPPSPALETPLSPPPE 541
Query: 625 -----PPAEEAPAEVQPPPAEEAPAEVQP------PPAEEAPAEVQPPPAEEAPAEVQP- 672
PP EE+P PP EE P P PP EE+P PP EE+P P
Sbjct: 542 ASPLSPPFEESPLS---PPPEELPTSPPPEASRLSPPPEESP---MSPPPEESPMSPPPE 595
Query: 673 -----PPAEEAPAEVQSLPAEETPIEETLAAVH-SPPADDVPAEEASVDK-HSPPADLLL 725
PP EE+P S P EE+P+ A SPP +D P + SPP ++
Sbjct: 596 ASRLFPPFEESPL---SPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSR 652
Query: 726 TEEFPIGEASAEVSPPPSE 744
P+ + +SPPP E
Sbjct: 653 LSPLPV---VSRLSPPPEE 668
Score = 82.8 bits (203), Expect = 1e-15
Identities = 156/624 (25%), Positives = 217/624 (34%), Gaps = 104/624 (16%)
Query: 193 SEHPEFQPATNSNEE-IGQKNISRTSFTQETKKGPPVL---LEDELREEVTVPVVQEGSA 248
S PE P + E + S S ET PP L E P +E
Sbjct: 504 SPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPT 563
Query: 249 VKKVASAEIEPPSTEKFPAKIQPPLVEEATAKAEPRPAEETHVQVQPSTEETPDAEAATA 308
++ + PP E + + PP E + + P A + S P E+ +
Sbjct: 564 SPPPEASRLSPPPEE---SPMSPP--PEESPMSPPPEASRLFPPFEESPLSPPPEESPLS 618
Query: 309 VAENSVKVQPPPAEEAPLVEFPAEIQ---PPSAEESPSVELLAEILPPSAE--------E 357
+ ++ PPP E++P+ P E PP + +++ + PP E E
Sbjct: 619 PPPEASRLSPPP-EDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEE 677
Query: 358 SPSEEPP-AEILPPPAEKSPSVELLGEIRSPSAQKAPIEVQPLPAEGA----LEEAPAKV 412
SP+ PP A L PP E SP+ SP + +P P P + LEE+P
Sbjct: 678 SPTSPPPEASRLSPPPEDSPT--------SPPPEDSP--ASPPPEDSLMSLPLEESPLLP 727
Query: 413 EP------PTVEETLADVQPLLPEEAPREE-------ARELQLSTAMETP---------- 449
P P E +P P +PR E A E LS E P
Sbjct: 728 LPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPH 787
Query: 450 -AEEAPTEFQSPLPKETTAEEASAEIQLLAATEPPA-DETPAEAR-SPLSEETSA----E 502
+ +A SP P+E + E L E P P E+ SP SEE E
Sbjct: 788 LSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPE 847
Query: 503 EAHA--EVQSPLAEETTAEEASAEIQLLAAIEAPADETPAEAQ-SPLSEETSAEEA---- 555
E+H E++ P + Q A E P P E SPL E + E
Sbjct: 848 ESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPP 907
Query: 556 ----PAEVQ-SPSAK-GVSIEEAPLELQPPSGEETTAEEASAAIQLLAATE----ASAEE 605
P E+ SPS + +S + P + PP A A+ L E A +
Sbjct: 908 LSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGELEYPFGAKGDS 967
Query: 606 APAEVQPPPAEEAPAEVQPPPA------EEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQ 659
P P E P + PPP E P + PP P E P +
Sbjct: 968 DPESPLAAPILETP--ISPPPEANCTDPEPVPPMILPPSPGSPVGPASPILMEPLPPQCS 1025
Query: 660 PPPAEEAPAEVQPPPAEEAPAEVQSLPAEETPIEETLAAVHSPPADDVPAEEASVDKHSP 719
P + PP PA S+P+ +PI + + +D+ E +K S
Sbjct: 1026 PLLQHSLVPQNSPPSQCSPPALPLSVPSPLSPIGKVVGV-----SDEAELHEMETEKVSE 1080
Query: 720 PADLLLTEEFPIGEASAEVSPPPS 743
P E P E SA SP PS
Sbjct: 1081 P-------ECPALEPSA-TSPLPS 1096
Score = 67.8 bits (164), Expect = 4e-11
Identities = 134/525 (25%), Positives = 184/525 (35%), Gaps = 92/525 (17%)
Query: 255 AEIEPPSTEKFPAKIQPPLVEEATAKAEPRPAEETHVQVQPSTEET-PDAEAATAVAENS 313
+ + PP E + + PP E T+ P E + + P T P E + A
Sbjct: 660 SRLSPPPEE---SPLSPPPEESPTSP----PPEASRLSPPPEDSPTSPPPEDSPASPPPE 712
Query: 314 VKVQPPPAEEAPLVEFPAEIQPPSAEESPSVELLAEI--LPPSAEE---SPSEEPPAEIL 368
+ P EE+PL+ P E Q E P + E L P EE SP E P +
Sbjct: 713 DSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEP-HLS 771
Query: 369 PPPAEKSPSVELLGEIRSPSAQKAPIEVQPLPAEGALEEAPAKVEP---PTVEETLADVQ 425
P P E P + + E S Q + P P E L +P EP P EE Q
Sbjct: 772 PQPEE--PCLCAVPEEPHLSPQAEGPHLSPQPEE--LHLSPQTEEPHLSPVPEEPCLSPQ 827
Query: 426 PLLPEEAPREEA-------RELQLSTAMETPAEEAPTEFQSPLPKETTAEEASAEIQLLA 478
P +P+ E E LS +E P SP P++ E Q A
Sbjct: 828 PEESHLSPQSEEPCLSPRPEESHLSPELEKPP-------LSPRPEKPPEEPG----QCPA 876
Query: 479 ATEPPADETPAE-ARSPLSEETSAEEAHAEVQSPLAEE---TTAEEASAEIQLLAAIEAP 534
E P P E + SPL E + E SPL EE + + E S QL+ P
Sbjct: 877 PEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLM-----P 931
Query: 535 ADETPAEAQSPLSEETSAEEAPA-----EVQSP-SAKGVSIEEAPLELQ--------PPS 580
D P PLS +A PA E++ P AKG S E+PL PP
Sbjct: 932 PDPLPP----PLSPIITAAAPPALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPE 987
Query: 581 GEETTAEEASAAIQLLAATEASAEEAPAEVQPPPAEEAPA-EVQPPPAEEAPAEVQPP-- 637
T E I + +P ++P P + +P + P P++ PP
Sbjct: 988 ANCTDPEPVPPMILPPSPGSPVGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPAL 1047
Query: 638 ----PAEEAP----------AEVQPPPAEEA---------PAEVQPPPAEEAPAEVQPPP 674
P+ +P AE+ E+ P+ P P+ P
Sbjct: 1048 PLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECPALEPSATSPLPSPMGDLSCPAPS 1107
Query: 675 AEEAPAEVQSLPAEETPIEETLAAVHSPPADDVPAEEASVDKHSP 719
A + L + P++ A P P AS K SP
Sbjct: 1108 PAPALDDFSGLGEDTAPLDGIDAPGSQPEPGQTPGSLASELKGSP 1152
Score = 58.9 bits (141), Expect = 2e-08
Identities = 70/223 (31%), Positives = 91/223 (40%), Gaps = 48/223 (21%)
Query: 565 KGVSIEEAPL--ELQPPSGEETTAEEASAAIQLLAATEASAEEA------PAEVQPPPAE 616
+ V+ + P+ PP +T +E A L A + + P E P E
Sbjct: 359 RSVAEQHTPVCSRFSPPEPGDTPTDEPDA---LYVACQGQPKGGHVTSMQPKEPGPLQCE 415
Query: 617 EAP---AEVQPPPAEEAPA-EVQP--PPAEEAPAEVQPPPAEEAPAEVQP------PPAE 664
P A VQ P EAP E P PP EE+P PP EE+P P PP E
Sbjct: 416 AKPLGKAGVQLEPQLEAPLNEEMPLLPPPEESPLS---PPPEESPTSPPPEASRLSPPPE 472
Query: 665 EAPAEVQPP------PAEEAPAEVQSLPAEETPIEETLAAVHSPPADDVPAEEASVDKHS 718
E PA P P EE+P S P EE+P+ + P ++ P S + S
Sbjct: 473 ELPASPLPEALHLSRPLEESPL---SPPPEESPLSPPPESSPFSPLEESP---LSPPEES 526
Query: 719 PPADLLLTEEFPIGEAS--------AEVSPPPSE--QTPEDEA 751
PP+ L T P EAS + +SPPP E +P EA
Sbjct: 527 PPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEA 569
Score = 46.2 bits (108), Expect = 1e-04
Identities = 113/537 (21%), Positives = 184/537 (34%), Gaps = 68/537 (12%)
Query: 220 QETKKGPPVLLEDELREEVTV----PVVQEGSAVKKVASAEIEPPSTEKFPAKIQPPLVE 275
Q+ ++ +L++ +L++ V P + G+ + P FP PL E
Sbjct: 4217 QQQQQLQALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQE 4276
Query: 276 EATAKAEPRPAEETHVQVQPSTEETPDAEAATAVAENSVKVQPPPAEEAPLVEFPAEIQP 335
A PRP P P +T V PPP+ P E +
Sbjct: 4277 LG---AGPRPQG-------PPRLPAPPGALSTGPVLGPVHPTPPPSS-------PQEPKR 4319
Query: 336 PSAEESPSVELLAEI-LPPSAEESPSEEPPAEILPPPAEKSPSVELLGEIRSPSAQKAPI 394
PS SPS +L E LPP+ +P + P + PPP SP+ L + S P
Sbjct: 4320 PSQLPSPSSQLPTEAQLPPTHPGTPKPQGPT-LEPPPGRVSPAAAQLADTLF-SKGLGPW 4377
Query: 395 EVQPLPAEGALEEAPAKVEPPTVEETLADVQPLLPEEAPREEARELQLSTAMETPAEEAP 454
+ AE E + V P +++ V P + + ++E RE + ++ EA
Sbjct: 4378 DPPDNLAETQKPEQSSLV-PGHLDQVNGQVVPEASQLSIKQEPREEPCALGAQSVKREAN 4436
Query: 455 TEFQSPLPKETTAEEASAEIQLLAATEPPADETPAE-----ARSPLSEETSAEEAHAEVQ 509
E P+ T+ LLA A + LS +E AE+
Sbjct: 4437 GE---PIGAPGTSNHL-----LLAGPRSEAGHLLLQKLLRAKNVQLSTGRGSEGLRAEIN 4488
Query: 510 SPLAEETTAEEASAEIQLLAAIEAPADETPAEAQSPLSEETSAEEAPAEVQSPSAKGVSI 569
+ + E + P+++ A A+ PL+ + P VQ S + VS
Sbjct: 4489 GHIDSKLAGLEQKLQ-------GTPSNKEDAAARKPLTPK------PKRVQKASDRLVSS 4535
Query: 570 EEAPLELQPPSGEETTAEEASAAIQLLAATEASAEEAPAEVQPPPAEEAPAEVQPPPAEE 629
+ + E ++ + LL TE A A + P P Q
Sbjct: 4536 RKKLRKEDGVRASEALLKQLKQELSLLPLTE-PAITANFSLFAPFGSGCPVNGQSQLRGA 4594
Query: 630 APAEVQPPPAEE-----APAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEA---PAE 681
+ P + + PP + PPP+ + P+EE P +
Sbjct: 4595 FGSGALPTGPDYYSQLLTKNNLSNPPTPPSSLPPTPPPSVQQKMVNGVTPSEELGEHPKD 4654
Query: 682 VQSLPAEETPIEET--------LAAVHSPPADDVPAEEASVDKHSPPADLLLTEEFP 730
S E + +T LAA+ +PP + D+ S D ++ P
Sbjct: 4655 AASARDSERALRDTSEVKSLDLLAALPTPPHNQTEDVRMESDEDSDSPDSIVPASSP 4711
Score = 41.2 bits (95), Expect = 0.004
Identities = 85/439 (19%), Positives = 149/439 (33%), Gaps = 76/439 (17%)
Query: 270 QPPLVEEATAKAEPRPAEETHVQVQPSTE-------ETPDAEAATAVAENSVKVQPPPAE 322
Q L+ ++ P+ ++ V + P +P A T + + PA
Sbjct: 3974 QMGLLNQSRTLLSPQQQQQQQVALGPGMPAKPLQHFSSPGALGPTLLLTGKEQNTVDPAV 4033
Query: 323 EAPLVEFPAEIQPPSAEESPSVELLAEILPPSAEESPSEEPPAEIL---PPPAEKSPSVE 379
+ E P+ Q + E +A E PS +++L P P + S++
Sbjct: 4034 SSEATEGPSTHQGGPLAIGTTPESMAT---EPGEVKPSLSGDSQLLLVQPQPQPQPSSLQ 4090
Query: 380 LLGEIRSPSAQKAPIEVQPLPAEGA-----------LEEAPAKVEPPTV---EETLADVQ 425
L +R P Q+ + + G+ P + P+V ++ + Q
Sbjct: 4091 LQPPLRLPGQQQQQVSLLHTAGGGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSMTQ 4150
Query: 426 PLLPEEAPREEARELQLSTAMETPAEEAPTEFQSPLPKE---TTAEEASAEIQLLAATEP 482
LL + P E R +Q +T + P + LP T + A++Q + A P
Sbjct: 4151 NLLGPQQPMLE-RPMQNNTGPQPPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNP 4209
Query: 483 PADETPAEARSPLSE---ETSAEEAHAEVQSPLAEETTAEEASAEIQLLAAIEAPADETP 539
+ + L + +++ A Q+P +E + ++ +Q L + P
Sbjct: 4210 QLRHLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQEPGTQ--TSPLQGLLGCQPQLGGFP 4267
Query: 540 AEAQSPLSEETSAEEAPAEVQSPSAKGVSIEEAPLELQPPSGEETTAEEASAAIQLLAAT 599
PL +E A P + P L P G +T
Sbjct: 4268 GPQTGPL-QELGAGPRP--------------QGPPRLPAPPGALSTGPVLG--------- 4303
Query: 600 EASAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQ 659
P PPP+ P + P+++ P P+ + P E Q PP + Q
Sbjct: 4304 -------PVHPTPPPSS--------PQEPKRPSQL-PSPSSQLPTEAQLPPTHPGTPKPQ 4347
Query: 660 PPPAEEAPAEVQPPPAEEA 678
P E P V P A+ A
Sbjct: 4348 GPTLEPPPGRVSPAAAQLA 4366
Score = 40.4 bits (93), Expect = 0.007
Identities = 31/98 (31%), Positives = 41/98 (41%), Gaps = 8/98 (8%)
Query: 574 LELQPPSGEETTAEEASAAIQLLAATEASAEEAPAEVQPPPAEEAPAEVQPP--PAEEAP 631
L+ + P+ E T + + L + SA P E PPP+ AP+ PP P E P
Sbjct: 4879 LKQESPAPEPPTQHSYTYNVSNLDVRQLSAPP-PEEPSPPPSPLAPSPASPPTEPLVELP 4937
Query: 632 AEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAE 669
E P AE P P P +P +P P P E
Sbjct: 4938 TE---PLAE--PPVPSPLPLASSPESARPKPRARPPEE 4970
Score = 39.3 bits (90), Expect = 0.015
Identities = 87/372 (23%), Positives = 133/372 (35%), Gaps = 73/372 (19%)
Query: 359 PSEEPPAEILPPPAEKSPSVELLGEIRSPSAQKAPIEVQPLPAEGALEEAPAKVEPPTVE 418
PS PP PPP+ + V + +PS E+ P + A + T E
Sbjct: 4623 PSSLPPT---PPPSVQQKMVNGV----TPSE-----ELGEHPKDAASARDSERALRDTSE 4670
Query: 419 ETLADVQPLLPEEAPREEARELQLSTAMETPAEEAPTEFQSPLPKETTAEEASAEIQLLA 478
D+ LP P + ++++ + ++ + ++ SP + EEA L +
Sbjct: 4671 VKSLDLLAALPTP-PHNQTEDVRMESDEDSDSPDSIVPASSP--ESILGEEAPRFPHLGS 4727
Query: 479 ATEPPADETPA-------EARSPLSEETSAEEAHA-EVQSPLAEETTAEEASAEIQLLAA 530
D + A P+ +T A EV L T + +E+ ++
Sbjct: 4728 GRWEQEDRALSPVIPLIPRASIPVFPDTKPYGALGLEVPGKLPVTTWEKGKGSEVSVMLT 4787
Query: 531 IEAPADET-------PAEAQS---PLSEETSAEEAPA----EVQSPSAKGVSIEEAPLEL 576
+ A A + AE S P S E E+PA E + A+G +E LE
Sbjct: 4788 VSAAAAKNLNGVMVAVAELLSMKIPNSYEVLFPESPARAGTEPKKGEAEGPGGKEKGLEG 4847
Query: 577 QPPSGEETTAEEASAAI-------QL----LAATEASAEEAPAE--------------VQ 611
+ P ++ A + QL L E+ A E P + +
Sbjct: 4848 KSPDTGPDWLKQFDAVLPGYTLKSQLDILSLLKQESPAPEPPTQHSYTYNVSNLDVRQLS 4907
Query: 612 PPPAEEAPAEVQPPPAEEAPAEVQPP--PAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAE 669
PP P E PPP+ AP+ PP P E P E P AE P P P +P
Sbjct: 4908 APP----PEEPSPPPSPLAPSPASPPTEPLVELPTE---PLAE--PPVPSPLPLASSPES 4958
Query: 670 VQPPPAEEAPAE 681
+P P P E
Sbjct: 4959 ARPKPRARPPEE 4970
Score = 38.9 bits (89), Expect = 0.020
Identities = 55/257 (21%), Positives = 85/257 (33%), Gaps = 22/257 (8%)
Query: 332 EIQPPSAEESPSVELLAEILP--PSAEESPSEEPPAEILPPPAEKSPSVELLGEIRSPSA 389
E++ P ++P +++ P P P E PPA+ L P P + G P A
Sbjct: 2320 ELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYA 2379
Query: 390 QKAPI--EVQPLPAEGALEEAPAKVEPPTVEETLADVQPLLPEEAPREEARELQLSTAME 447
Q P+ QP P E P + A Q ++P LS
Sbjct: 2380 Q-PPLTPRPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSP---LTPRPLSAEAF 2435
Query: 448 TPAEEAPTEFQSPLPKETTAEEASAEIQLLAATEPPADETPAEARSPLSEETSAEEAHAE 507
P+ P FQSP P + +PP + P A + AH
Sbjct: 2436 CPSPVTP-RFQSPDPYSRPPSRPQSRDPFAPLHKPPRPQPPEVAFK------AGSLAHTS 2488
Query: 508 VQSPLAEETTAEEASAEIQLLAAIEAPADETPAEAQSPLSEETSAEEAPAEVQSPSAKGV 567
+ + + E+ + P+ + P +SP + +P P A G
Sbjct: 2489 LGAGGFPAALPAGPAGELH----AKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGE 2544
Query: 568 SIEEAPLE---LQPPSG 581
+ P+ L PP G
Sbjct: 2545 PSLKPPVPQPGLPPPHG 2561
Score = 37.4 bits (85), Expect = 0.057
Identities = 73/341 (21%), Positives = 112/341 (32%), Gaps = 48/341 (14%)
Query: 445 AMETPAEEAPTEFQSPLPKETTAEEASAEIQLLAATEPPADETPAEARSPLSEETSAEEA 504
A P ++P E LP + A+ S + LA P P +P +
Sbjct: 2147 AGSVPGPDSPGELFLKLPPQVPAQVPSQDPFGLAPAYPLEPRFPT---APPTYPPYPSPT 2203
Query: 505 HAEVQSPLAEETTAEEASAEIQLLAAIEAPADETPAEAQSPLSEETSAEEAPAEVQSPSA 564
A Q P+ ++ A + P+ L + + A +SP
Sbjct: 2204 GAPAQPPMLGASSRPGAGQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGV 2263
Query: 565 KGVSIEEAPLELQPPSGEETTAEEASAAIQLLAATEASAEEAPAEVQPPPAEE--APAEV 622
G E PL PP GE A E +L A++ + V P + E+
Sbjct: 2264 GGGKASE-PLLSPPPFGESRKALEVKKE-ELGASSPSYGPPNLGFVDSPSSGTHLGGLEL 2321
Query: 623 QPPPAEEAP-----AEVQPP-------PAEEAPAEVQPPPAEEAP--------------- 655
+ P +AP ++V+P P E PA+ P P
Sbjct: 2322 KTPDVFKAPLTPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQP 2381
Query: 656 ---AEVQPPPAEEA----PAEVQPPPAEEAPAEVQSLPAEETPI-EETLAAVHSPPADDV 707
QPPP E P + P PA QS + ++P+ L+A P+
Sbjct: 2382 PLTPRPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVT 2441
Query: 708 PAEEASVDKHSPPADLLLTEEFPIGEASAEVSPPPSEQTPE 748
P ++ PP+ + F A + PP Q PE
Sbjct: 2442 PRFQSPDPYSRPPSRPQSRDPF------APLHKPPRPQPPE 2476
Score = 35.8 bits (81), Expect = 0.17
Identities = 81/405 (20%), Positives = 123/405 (30%), Gaps = 75/405 (18%)
Query: 364 PAEILPPPAEKSPSVELLGEIRSPSAQKAPIEVQPLPAEGALEEAPAKVEPPTVEETLAD 423
P +LPPPA L S +P+E + P G P T + ++
Sbjct: 2612 PPSVLPPPAPDGSLPYLSHGASQRSGITSPVEKREDPGTGMGSSLATAELPGTQDPGMSG 2671
Query: 424 V-QPLLPEEAPREEARELQLSTAMETPAEEAPTEFQSPLPKETTAEEASAEIQLLAATEP 482
+ Q L ++ R+ REL + + + + T +E A P
Sbjct: 2672 LSQTELEKQRQRQRLRELLI---------------RQQIQRNTLRQEKETAAAAAGAVGP 2716
Query: 483 PADETPAEARSPLSEETSAEEAHAEVQSPLAEETTAEEASAEIQLLAAIEAPADETPAEA 542
P AE SP E+ S + + + +L P+D+ +
Sbjct: 2717 PG-SWGAEPSSPAFEQLSRGQTPFAGTQDKSSLVGLPPSKLSGPILGPGSFPSDDRLSRP 2775
Query: 543 QSPLSEETSAEEAPAEVQSPSAKGVS---IEEAP----LELQPPSGEETTAEEASAAIQL 595
P A + +V S G S + AP L LQ + ++A+AA +
Sbjct: 2776 PPP------ATPSSMDVNSRQLVGGSQAFYQRAPYPGSLPLQQQQQQLWQQQQATAATSM 2829
Query: 596 LAATEASAEEAP----------------AEVQPPPAEEAPAEVQPPPAEEAPAEVQ---- 635
A A P + P P E P P E VQ
Sbjct: 2830 RFAMSARFPSTPGPELGRQALGSPLAGISTRLPGPGEPVPGPAGPAQFIELRHNVQKGLG 2889
Query: 636 ----PPPAEEAPAEVQPPPAEEAPAEVQP------------------PPAEEAPAEVQPP 673
P P + P + P E P + P PPA E + P
Sbjct: 2890 PGGTPFPGQGPPQRPRFYPVSEDPHRLAPEGLRGLAVSGLPPQKPSAPPAPELNNSLHPT 2949
Query: 674 PAEEAPAEVQSLPAEETPIEETLAAVHSP---PADDVPAEEASVD 715
P + P L P T +P A +P E+ +D
Sbjct: 2950 PHTKGPTLPTGLELVNRPPSSTELGRPNPLALEAGKLPCEDPELD 2994
Score = 32.3 bits (72), Expect = 1.8
Identities = 49/214 (22%), Positives = 77/214 (35%), Gaps = 27/214 (12%)
Query: 541 EAQSPLSEETSAEEAPAEVQSPSAKGVSIEEAPLELQPPSGEETTAEEASAAIQLLAA-- 598
+A+S ++++T + + P+ L + P G + A+A + +
Sbjct: 2079 QAESQINKQTKVGDIARKTDRPALH--------LRIPPQPGALGSPPPAAAPTIFIGSPT 2130
Query: 599 TEASAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEV-QPPPAEEAPAE 657
T A + PPA P ++P E+ + PA+V P APA
Sbjct: 2131 TPAGLSTSADGFLKPPAGSVPGP-------DSPGELFLKLPPQVPAQVPSQDPFGLAPAY 2183
Query: 658 VQPPPAEEAPAEVQPPPAEE-APAEVQSLPAEETPIEETLAAVHSPPADDVPAEEASVD- 715
P AP P P+ APA+ L A P H+ P + ++ D
Sbjct: 2184 PLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPGAGQPGEFHTTPPGTPRHQPSTPDP 2243
Query: 716 ---KHSPPADLLLTEEFP-IGEASAE---VSPPP 742
P D L E P +G A +SPPP
Sbjct: 2244 FLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPP 2277
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 97.8 bits (242), Expect = 4e-20
Identities = 136/531 (25%), Positives = 197/531 (37%), Gaps = 56/531 (10%)
Query: 239 TVPVVQEGSAVKKVASAEIEPPSTEKFP--AKIQPPLVEEATAKAEPRPAEETHVQVQPS 296
T P + G A A P +T P PP T A P+ + + PS
Sbjct: 1132 TPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLAT-PS 1190
Query: 297 TEETPDAEAATAVAENSVKVQPPP--AEEAPLVEFPAE---IQPPSAEESPSVELLAEIL 351
+ P AAT + P P A P P+ + PS + +P+
Sbjct: 1191 PKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAAT--- 1247
Query: 352 PPSAEESPSEEPPAEILPPPAEKSPSVELLGEIRSPSAQKAP---IEVQPLPAEGALEEA 408
PPS + P+ PP PPA PS++ G + +P + AP + P P G
Sbjct: 1248 PPSPKGGPATPPPKGAPTPPAATPPSLK--GGLATPPHKGAPNPAVVTPPSPKGG----- 1300
Query: 409 PAKVEPPTVEETLADVQPLLPEEAPREEARELQLSTAMETPAEEAPTE--FQSPLPKETT 466
PA PP T P P+ +P P + APT P PK T
Sbjct: 1301 PA-TSPPKGAPTPPAATPPSPKGSPGTP------------PPKGAPTPPAVTPPSPKGTP 1347
Query: 467 AEEASAEIQLLAATEPPADETPAE-ARSPLSEETSAEEAHAEVQSPLAEETTAEEASAEI 525
A+ T P + E P A +P + A + + P + S +
Sbjct: 1348 TLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAV 1407
Query: 526 QLLAAIEAPADETPAEAQSPLSEETSAEEAPAEVQSPSAKGVSIEEAPLELQPPSGEETT 585
L+ +APA +P++ E +A + ++ P+ VS+++AP P G T
Sbjct: 1408 IPLSPKKAPA--------TPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATP 1459
Query: 586 AEEASAAIQLLAATEASAEEAPAEVQPPPA---EEAPAEVQPPPAEEAPAEVQPPPAEEA 642
+ + + A T S +E PA Q + ++APA P A PA + P +E
Sbjct: 1460 SSKGDPTLP--AVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSP-KEV 1516
Query: 643 PA---EVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQSLPAEETPIEETLAAV 699
PA + P A A + PA AP E PPA P+ + PA TP +E A
Sbjct: 1517 PATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSP-KKTPAIPTP-KEAPATP 1574
Query: 700 HSPPADDVPAEEASVDKHSPPADLLLTEEFPIGEASAEVSPPPSEQTPEDE 750
S A PA S K +P LL + E PP+ P E
Sbjct: 1575 SSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPE 1625
Score = 80.9 bits (198), Expect = 5e-15
Identities = 152/700 (21%), Positives = 233/700 (33%), Gaps = 90/700 (12%)
Query: 79 VEEKKEVKLVEETVVPEEKSADVREAAIELPES--VQDVEIPPNIPSVQLKMDRSQQTSR 136
+E LV V P+E S V + +P S + D E N+PS L +Q+ +
Sbjct: 475 IEPTSPAALVMAPVAPKEPSTQVA-TTLRIPVSPPLPDPEDLKNLPSSVLVKFPTQKDLQ 533
Query: 137 TGYWTMMNIP--PVEK--VDKEQQTYFSESEIVVISRPDSSSTKSK-------EDALKHK 185
T ++ P P + K+ T + + P ST S E L K
Sbjct: 534 TVPASLEGAPFSPAQAGLTTKKDPTVLPLVQAAPKNSPSFQSTSSSPEIPLSPEATLAKK 593
Query: 186 SSGKIFASEHPEFQPATNSNEEIGQKN----ISRTSFTQETKKGPPVLLEDELREEVTVP 241
S G+ P +PA++ +G + I S+ GP LL+ L
Sbjct: 594 SLGEPL----PIGKPASSMTSPLGVNSSASVIKTDSYAGPDSAGP--LLKSSLITPTVAA 647
Query: 242 VVQEGSAVKKVASAEIEPPSTEKFPAKIQPPLVEEATAKAEPRPAEETHVQVQP----ST 297
E + VA + ST + P L + + P +E + P ++
Sbjct: 648 FPLESADPAGVAPTTAKGTST--YTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTAS 705
Query: 298 EETPDAEAA--TAVAENSVKVQPPPAEEAPLVEFPAEIQPPSAEESPSVELLAEILP--P 353
E P A + T ++ + P + P P PP ++ + + + P
Sbjct: 706 ENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVAS 765
Query: 354 SAEESPSEEPPAEILPPPAEKSPSVELLGEIRSPSAQKAPIEVQPLPAEGALEEAPAKVE 413
S +E P+E+ A A ++ L + SP + V P ++ A +
Sbjct: 766 SPKECPTEDSGASAT---ASSKGTLTYLADSPSPLG----VSVSPQTKRPPTKKGSAGPD 818
Query: 414 PPTVEETLADVQPLLPEEAPREEARELQLSTAMETPAE-EAPTEFQSPLPKETTAEEASA 472
P + P+ P EA L + ++PA +PT P PK A
Sbjct: 819 TPIGNLS----SPVSPVEASFLPENSLSFQGSKDSPATTHSPTP---PSPKGAPTPSAVT 871
Query: 473 EIQLLAATEPPADE-TPAEARSPLSEETSAEEAHAEVQSPLAEETTAEEASAEIQLLAAI 531
+ T PP + TP+ P +E A T A + + + + ++
Sbjct: 872 PLSPKGVTLPPKETPTPSVVNLPFPKEGPA--------------TPAPKQAPALSMTSSS 917
Query: 532 EAPADETPAEAQSPLSEETSAEEAPAEVQSPSAKGVSIEEAPLELQPPSGEETTAEEASA 591
A TPA P S P PS KG +P P
Sbjct: 918 PKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPP----------- 966
Query: 592 AIQLLAATEASAEEAPAEVQPPPAEEAPAEVQPP----PAEEAPAEVQPPPAEEAPAEVQ 647
AAT S + PA P A PA P PA +P PPA P+
Sbjct: 967 -----AATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKG 1021
Query: 648 PPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQSLPAEETPIEE------TLAAVHS 701
P A P PPA P+ P A P + PA P + +L +
Sbjct: 1022 SPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPT 1081
Query: 702 PPADDVPAEEASVDKHSPPADLLLTEEFPIGEASAEVSPP 741
PPA P+ + SP + P +PP
Sbjct: 1082 PPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPP 1121
Score = 78.2 bits (191), Expect = 3e-14
Identities = 124/498 (24%), Positives = 164/498 (32%), Gaps = 33/498 (6%)
Query: 259 PPSTEKFPAKIQPPLVEEATAKAEPRPAEETHVQVQPSTEETPDAEAATAVAENSVKVQP 318
PPS + PA P A P P PS + P AAT + P
Sbjct: 947 PPSPKGGPATPSPKWAPTPPAATPPSPKGGP---ATPSPKGAPTPPAATPPSPKGGPATP 1003
Query: 319 PPAEEAPLVEFPAEIQPPSAEESPSVELL---AEILPPSAEESPSEEPPAEILPPPAEKS 375
P + AP P + PPS + SP+ A P + SP P A LP A +
Sbjct: 1004 SP-KGAPT---PPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTT 1059
Query: 376 PSVELLGEIRSPSAQKAPIEVQPLPAEGALEEAPAKVEPPTVEETLADVQPLLPEEAPRE 435
P+ L SP A ++ P A K P T A + P +P+
Sbjct: 1060 PAATL----PSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKG 1115
Query: 436 EARELQLSTAMETPAEEAPTE---FQSPLPK--ETTAEEASAEIQLLAATEPPADETPAE 490
A TPA P+ +P PK TT + AT PP
Sbjct: 1116 GLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTP 1175
Query: 491 ARSPLSEETSAEEAHAEVQSPLAEETT--AEEASAEIQLLAAIEAPADETPAEAQSPLSE 548
A +P S + SP TT A S + L A TPA A P +
Sbjct: 1176 AATPPSPKGGLA-----TPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPA-ATPPSPK 1229
Query: 549 ETSAEEAPAEVQS-PSAKGVSIEEAPLELQPPSGEETTAEEASAAIQ-LLAATEASAEEA 606
A +P + P+A S + P PP G T +++ LA
Sbjct: 1230 GGLATPSPKGAPTTPAATPPSPKGGPAT-PPPKGAPTPPAATPPSLKGGLATPPHKGAPN 1288
Query: 607 PAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEA 666
PA V PP + PA PP P PP + +P PP P V PP +
Sbjct: 1289 PAVVTPPSPKGGPA-TSPPKGAPTPPAATPPSPKGSPG-TPPPKGAPTPPAVTPPSPKGT 1346
Query: 667 PAEVQPPPAEEAPAEVQSLPAEETPIEETLAAVHSPPADDVPAEEASVDKHSPPADLLLT 726
P P+ + S TP T + PA P+ + SP D
Sbjct: 1347 PTLPATTPSSKGGPTTPSSKEGPTPPAAT-PSHKGGPAMTPPSPKRGPAIPSPKGDPTSP 1405
Query: 727 EEFPIGEASAEVSPPPSE 744
P+ A +P E
Sbjct: 1406 AVIPLSPKKAPATPVTRE 1423
Score = 75.5 bits (184), Expect = 2e-13
Identities = 112/505 (22%), Positives = 157/505 (31%), Gaps = 51/505 (10%)
Query: 259 PPSTEKFPAKIQPPLVEEATAKAEPRPAEETHVQVQPSTEETPDAEAATAVAENSVKVQP 318
PPS + PA P A P P P TP A A + S P
Sbjct: 993 PPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPA-ATPPSPKGSPAATP 1051
Query: 319 PP--AEEAPLVEFPAEIQPPSAEESPSVELLAEILPPSAEESPSEEPPAEILPPPAEKSP 376
P A P P+ P+ PPS + P+ P PPA P
Sbjct: 1052 LPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPP 1111
Query: 377 SVELLGEIRSPSAQKAPIEVQPLPA--EGALEEAPAKVEPPTVEETLADVQ--------- 425
S + G + +P + AP P +G L P K P T T +
Sbjct: 1112 SPK--GGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPK 1169
Query: 426 --PLLPEEAPREEARELQLSTAMETPAEEAPTEFQSPLPKETTAEEASAEIQLLAATEPP 483
P P P L + P A T P PK A + A PP
Sbjct: 1170 GAPTTPAATPPSPKGGLATPSPKGAPTTPAATP---PSPKGGLATPSPKGAPTTPAATPP 1226
Query: 484 ADE----TPAEARSPLSEETSAEEAHAEVQSPLAEETTAEEASAEIQLLAAIEAPADE-- 537
+ + TP+ +P + + +P + A+ L + P +
Sbjct: 1227 SPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGA 1286
Query: 538 -------TPAEAQSPLSEETSAEEAPAEVQSPSAKGV------SIEEAPLELQPPSGEET 584
P+ P + P PS KG P + PPS + T
Sbjct: 1287 PNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGT 1346
Query: 585 TAEEASAAIQLLAATEASAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPA 644
A+ T S++E P P+ + + PP + PA P +PA
Sbjct: 1347 PTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPA 1406
Query: 645 EVQPPPAEEAPA-------EVQPPPAEEAPAEVQPPPAEEAPAEVQSLPAEETPI---EE 694
V P ++APA P + P V P ++APA TP +
Sbjct: 1407 -VIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDP 1465
Query: 695 TLAAVHSPPADDVPAEEASVDKHSP 719
TL AV P + PA + SP
Sbjct: 1466 TLPAVTPPSPKEPPAPKQVATSSSP 1490
Score = 74.3 bits (181), Expect = 4e-13
Identities = 114/532 (21%), Positives = 183/532 (34%), Gaps = 67/532 (12%)
Query: 227 PVLLEDELREEVTVPVVQEGSAVKKVASAEIEPPSTEKFPAKIQPPLVEEATAKAEPRPA 286
P ++ ++ PV +EG+A + ++ PP+ + P +++A A + P+
Sbjct: 1405 PAVIPLSPKKAPATPVTREGAATP--SKGDLTPPA-------VTPVSLKKAPATSAPKGG 1455
Query: 287 EETHVQVQPSTEETPDAEAATAVAENSVKVQPPPAEEAPLVEFPAEIQPPSAEESPSVEL 346
T PS++ P A T PP +E P + A P + +
Sbjct: 1456 PAT-----PSSKGDPTLPAVT----------PPSPKEPPAPKQVATSSSPKKAPATPAPM 1500
Query: 347 LAEILPPSAEESPSEEPPAEILPPPAEKSPSVELLGEIRSPSAQKAPIEVQPLPAEGALE 406
A LP SP E P P+ + R P A A + + PA A +
Sbjct: 1501 GAPTLPAVIPSSPKEVPAT-----PSSR----------RDPIAPTATLLSKKTPATLAPK 1545
Query: 407 EAPAKVEPPTVEETLADVQPLLPEEAPREEARELQLSTAMETPAEEAPTEFQSPLPKETT 466
EA + PP + P +P P+E A PA T +P PKE
Sbjct: 1546 EA---LIPPAMTVPSPKKTPAIP--TPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELL 1600
Query: 467 AEEASAEIQLLAATEPPADETPAEARSPLSEETSAEEAHAEVQSPLAEETTAEEASAEIQ 526
A A PPA P+ + P + V +++ AS +
Sbjct: 1601 IPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCK 1660
Query: 527 LLAAIEAPADETPAEAQSPLSEETSAEEAPAE---VQSPSAKGVSIEEAPLELQPPSGEE 583
+ A + + PA+ +E AP + +P+ KG +++ PP +
Sbjct: 1661 MGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSS-ATSPPICPD 1719
Query: 584 TTAEEASAAIQLLAATEASAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQ-PPPAEEA 642
+A+ S +T A A P + + P AP E + P A
Sbjct: 1720 PSAKNGSKG---PLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAA 1776
Query: 643 PAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQSLPAEETPIEETLAAVHSP 702
E P E A P P P + P P P + Q LP+ + E SP
Sbjct: 1777 AFEKVLPKPESASVSAAPSPPVSLP--LAPSPVPTLPPKQQFLPSSPGLVLE------SP 1828
Query: 703 PADDVPAEEASVDKHSPPADL-------LLTEEFPIGEASAEVSPPPSEQTP 747
PA+E + PP + + P +++ P PS + P
Sbjct: 1829 SKPLAPADEDELLPLIPPEPISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQP 1880
Score = 49.7 bits (117), Expect = 1e-05
Identities = 118/556 (21%), Positives = 198/556 (35%), Gaps = 78/556 (14%)
Query: 240 VPVVQEGSAVKKVASAEIEPPSTEKFPAKIQPPLVEEATAKAEPRPAEETHVQVQPSTEE 299
VP Q S E P+ P I PP+ A A A P + P+ +
Sbjct: 80 VPFPQSSSGTALPLGTAPEAPTF--LPNLIGPPISPAALALASP--------MIAPTLKG 129
Query: 300 TPDAEAATAVAENSVKVQPPPAEEAPLVEFPAEI--QPPSAE--ESPSVELLAEILPPSA 355
TP + A A+ V + P +++ FP + PPS ES SV L+ + PS
Sbjct: 130 TPSSSAPLAL----VALAPHSVQKSSA--FPPNLLTSPPSVAVAESGSVITLSAPIAPSE 183
Query: 356 EESPSEEPPAEILP-PPAEKSP-----SVELLGEIRSPSAQKAPIEVQPLPAEGALEEAP 409
++ + P+E++P P SP +V S Q + L A
Sbjct: 184 PKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCVTPMASIQSGVASLPQTTPTTTLAIAS 243
Query: 410 AKVEPPTVEETLADVQ---------PLLPEEAPREEARELQLST-AMETPAEEAPTEFQS 459
+V+ T+ L Q P+ P A + L + T + +T P +F
Sbjct: 244 PQVKDTTISSVLISPQNPGSLSLKGPVSPPAALSLSTQSLPVVTSSQKTAGPNTPPDFPI 303
Query: 460 PLPKETTA--EEASAEIQLLAATEPPA--DETPAEARSPLSEETSAEEAHAEVQSPLAEE 515
L + + +QLL T P A D T S ++ + V PL
Sbjct: 304 SLGSHLAPLHQSSFGSVQLLGQTGPSALSDPTVKTISVDHSSTGASYPSQRSVIPPLPSR 363
Query: 516 TTAEEASAEIQLLAAIEAPADETPAEAQS-------PLSEETSAEEAPAEVQSPSAKGVS 568
E A + + D+ P+ S L+ TS +P + +
Sbjct: 364 N--EVVPATVAAFPVVAPSVDKGPSTISSITCSPSGSLNVATSFSLSPTTSLILKSSPNA 421
Query: 569 IEEAPLELQPPSGEETTAEEASAAIQLLAATEASAEEAPAEVQPPPAEEAPAEVQP-PPA 627
PL Q P T +AA + E V PP + + ++P PA
Sbjct: 422 TYHYPLVAQMPVSSVGTTPLVVTNPCTIAAAPTTTFEVATCVSPPMSSGPISNIEPTSPA 481
Query: 628 EEAPAEVQP-PPAEEAPAEVQPP--PAEEAPAEVQPPPA------------EEAPAEVQP 672
A V P P+ + ++ P P P +++ P+ + PA ++
Sbjct: 482 ALVMAPVAPKEPSTQVATTLRIPVSPPLPDPEDLKNLPSSVLVKFPTQKDLQTVPASLEG 541
Query: 673 PPAEEAPAEVQS------LPAEETPIEETLAAVHSPPADDVP-AEEASVDKHSPPADLLL 725
P A A + + LP + + + + + + ++P + EA++ K S L
Sbjct: 542 APFSPAQAGLTTKKDPTVLPLVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKS------L 595
Query: 726 TEEFPIGEASAEVSPP 741
E PIG+ ++ ++ P
Sbjct: 596 GEPLPIGKPASSMTSP 611
Score = 40.4 bits (93), Expect = 0.007
Identities = 87/463 (18%), Positives = 160/463 (34%), Gaps = 52/463 (11%)
Query: 336 PSAEESPSVELLAEILPPSAEESPSEEPPAEILPPPAEKSPSVELLGEIRSPSAQKAPIE 395
PSA P+V+ ++ + PS+ LP E P+ + +PS K P
Sbjct: 328 PSALSDPTVKTISVDHSSTGASYPSQRSVIPPLPSRNEVVPATVAAFPVVAPSVDKGPST 387
Query: 396 VQPLPA--EGALEEAPAKVEPPTVEETLADVQPLLPEEAPREEARELQLSTAMETPAEEA 453
+ + G+L A + PT L+ + +P ++ +
Sbjct: 388 ISSITCSPSGSLNVATSFSLSPTTS--------LILKSSPNATYHYPLVAQMPVSSVGTT 439
Query: 454 PTEFQSPLPKETTAEEASAEIQLLAATEPPADETPAEARSPLSEETSAEEAHAEVQSPLA 513
P +P T A + ++ PP P P S A V +P+A
Sbjct: 440 PLVVTNPC---TIAAAPTTTFEVATCVSPPMSSGPISNIEPTSPA-------ALVMAPVA 489
Query: 514 EETTAEEASAEIQLLAAIEAPADE----TPAEAQSPLSEETSAEEAPAEVQ----SPSAK 565
+ + + + +++ + P E P+ + + PA ++ SP+
Sbjct: 490 PKEPSTQVATTLRIPVSPPLPDPEDLKNLPSSVLVKFPTQKDLQTVPASLEGAPFSPAQA 549
Query: 566 GVSIEEAPLEL---QPPSGEETTAEEASAAIQLLAATEASAEEAPAEVQPPPAEEAPAEV 622
G++ ++ P L Q + + S++ ++ + EA+ + +P P + + +
Sbjct: 550 GLTTKKDPTVLPLVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLG-EPLPIGKPASSM 608
Query: 623 QPPPAEEAPAEVQPPPAEEAPAEVQP--------PPAEEAPAEVQPPPAEEAPAEVQPPP 674
P + A V + P P P P E PA AP +
Sbjct: 609 TSPLGVNSSASVIKTDSYAGPDSAGPLLKSSLITPTVAAFPLE-SADPAGVAPTTAKGTS 667
Query: 675 AEEAPAE-----VQSLPAEETPIEE-TLAAVHSPP--ADDVPAEEASVDKHSPPADLLLT 726
A SL + P++E TL + P +++ P + + +P A L+L
Sbjct: 668 TYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLA 727
Query: 727 EEFPIGEASAEVSPPPSEQTPEDEALVENVSTEFQSPQVAGIP 769
E P S + P TP V+ +S VA P
Sbjct: 728 PEIPKSVPSPSL---PPAGTPPGTKKVDGISHTSALAPVASSP 767
Score = 34.3 bits (77), Expect = 0.48
Identities = 54/217 (24%), Positives = 74/217 (34%), Gaps = 34/217 (15%)
Query: 575 ELQPPSGEETTAEEASAAIQLLAATEASAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEV 634
EL P E +SA L+ T A + P PPP AP + A +A
Sbjct: 15 ELPQPQAETAVLPMSSA----LSVTAALGQPGPT--LPPPCSPAPQQCPLSAANQASPFP 68
Query: 635 QPPPAEEAPAEVQPPPAEEA---PAEVQPPPAEEAPAEVQPP--PAEEAPAE------VQ 683
P P EV P + P P P + PP PA A A ++
Sbjct: 69 SPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALALASPMIAPTLK 128
Query: 684 SLPAEETPIEETLAAVH--------------SPPADDVPAEEASVDKHSPPADLLLTEEF 729
P+ P+ A H SPP+ V AE SV S P +
Sbjct: 129 GTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAV-AESGSVITLSAPI-APSEPKT 186
Query: 730 PIGEASAEVSPPPSEQTPEDEALVENVSTEFQSPQVA 766
+ + +EV P P + TP +V V +P +
Sbjct: 187 NLNKVPSEVVPNP-KGTPSPPCIVSTVPYHCVTPMAS 222
Score = 33.1 bits (74), Expect = 1.1
Identities = 44/190 (23%), Positives = 61/190 (32%), Gaps = 12/190 (6%)
Query: 602 SAEEAPAEVQPPPAEEAPAEVQP-------PPAEEAPAEVQPPPAEEAPAEVQPPPAEEA 654
+ E PA Q P +A V P A P PPP AP + A +A
Sbjct: 5 ATETVPATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAANQA 64
Query: 655 PAEVQPPPAEEAPAEVQPPPAEEAPA-EVQSLPAEETPIEETLAAVHSPPADDVPAEEAS 713
P P EV P + A + + P T + + SP A + + +
Sbjct: 65 SPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALALASPMIA 124
Query: 714 VDKHSPP---ADLLLTEEFPIGEASAEVSPPPSEQTPEDEALVENVST-EFQSPQVAGIP 769
P A L L P + PP +P A+ E+ S +P P
Sbjct: 125 PTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSAPIAPSEP 184
Query: 770 AVKLGSVVLE 779
L V E
Sbjct: 185 KTNLNKVPSE 194
Score = 32.7 bits (73), Expect = 1.4
Identities = 87/445 (19%), Positives = 141/445 (31%), Gaps = 62/445 (13%)
Query: 332 EIQPPSAEESPSVELLAEILPPSAEESPSEE--PPAEILPPPAEKSPSVELLGEIRSPSA 389
E P + +E P + +LP S+ S + P LPPP SP+
Sbjct: 7 ETVPATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPC-------------SPAP 53
Query: 390 QKAPI----EVQPLPAEGALEEAPAKVEPPTVEETLADVQPLLPEEAPREEARELQLSTA 445
Q+ P+ + P P+ + P +V P A L L TA
Sbjct: 54 QQCPLSAANQASPFPSPSTIASTPLEVPFPQSSSGTA-----------------LPLGTA 96
Query: 446 METPAEEAPTEFQSPLPKETTAEEASAEIQLLAATEPPADETPAEARSPLSEETSAEEAH 505
E P P P+ A + L T + A +P S + S+
Sbjct: 97 PEAPT-FLPNLIGPPISPAALALASPMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPP 155
Query: 506 AEVQSPLAEETTAEEASAEIQLLAAIEAPADETPAEAQSPLSEETSAEEAPAEVQSPSAK 565
+ SP E+ + I L A I +P +T+ + P+EV P+ K
Sbjct: 156 NLLTSP--PSVAVAESGSVITLSAPI------------APSEPKTNLNKVPSEV-VPNPK 200
Query: 566 GVSIEEAPLELQPPSGEETTAEEASAAIQLLAATEASA-EEAPAEVQPPPAEEAPAEVQP 624
G + P A S L T + A +V+ Q
Sbjct: 201 GTPSPPCIVSTVPYHCVTPMASIQSGVASLPQTTPTTTLAIASPQVKDTTISSVLISPQN 260
Query: 625 PPAEEAPAEVQPPPAEEAPAEVQP--PPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEV 682
P + V PP A + P +++ PP + P + + V
Sbjct: 261 PGSLSLKGPVSPPAALSLSTQSLPVVTSSQKTAGPNTPPDFPISLGSHLAPLHQSSFGSV 320
Query: 683 QSL-----PAEETPIEETLAAVHSPPADDVPAEEASVDKHSPPADLL--LTEEFPIGEAS 735
Q L A P +T++ HS P++ + + +++ FP+ S
Sbjct: 321 QLLGQTGPSALSDPTVKTISVDHSSTGASYPSQRSVIPPLPSRNEVVPATVAAFPVVAPS 380
Query: 736 AEVSPPPSEQTPEDEALVENVSTEF 760
+ P + NV+T F
Sbjct: 381 VDKGPSTISSITCSPSGSLNVATSF 405
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 96.7 bits (239), Expect = 8e-20
Identities = 141/624 (22%), Positives = 234/624 (37%), Gaps = 73/624 (11%)
Query: 168 SRPDSSSTKSKEDALKHKSSGKIFASEHPEFQPATNSNEEIGQKNISRTSFTQETKKGPP 227
SRP +S + K+ S G + + P T +GQK + R S + +G
Sbjct: 92 SRPPASGRGERAPPAKNTSPGPVSS---PGRASGTTRPGPLGQKGL-RISAEETVARGKA 147
Query: 228 V------LLEDELREEVTVPVVQEGSAV----KKVASAEIEPPSTEKFPAKIQPPLVEEA 277
L R + + P S + A E+ P A+ +PP E
Sbjct: 148 TEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAP-SARPRPPT--EG 204
Query: 278 TAKAEPRPAEETHVQVQPSTEETPDAEAATA-VAENSVKVQPPPAEEAPLVEFPAEIQPP 336
K+ +E + + P+ P A A S+ P +P P+ P
Sbjct: 205 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLS-SPARSGPSARGTP 263
Query: 337 SAEESPSVELLAEILPPSAEESPSEEPPAEILPPPAEKSPSVELLGEIRSPSAQKAP--I 394
A PS P + + PP ++ PP + +P++ L SP A +P
Sbjct: 264 RAPAHPS--------QPKPKGLQALRPP-QVTPPRKDAAPALGPLSS--SPLATPSPSGT 312
Query: 395 EVQPLPA-EGALEEAPAKVEPPTVEETLADVQPLLPEEAPREEARELQLSTAMETPAEEA 453
+ +P+P + A PA + P T + P P P + L + TP +A
Sbjct: 313 KARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQT----LPSPPATPPSQA 368
Query: 454 PTEFQSPLPKETTAEEASAEIQLLAATEPPADETPAEARSPLSEETSAEEAHAEVQSPLA 513
P +P + + + IQ+ + P+ + P SPL+ S+ +A + SP
Sbjct: 369 PPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPP---SPLA--LSSLQATTSLGSPTL 423
Query: 514 EETTAEEASAEIQLLAAIEAPADETPAEAQSPLSEETSAEEAPAEVQSPSAKGVSIEEAP 573
+ T + + Q A++ +P+ SP + + A +Q+ + VS +P
Sbjct: 424 QATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSP 483
Query: 574 LELQPPSGEETTAEEASAAIQLLAATEASAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAE 633
L + P +Q L++ + + +AP P E + + PP + PA
Sbjct: 484 LTIHP--------------LQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPAS 529
Query: 634 VQPPPAEEAPAEVQPPPAEEAPAEVQPP----PAEEAPAEVQPPPAEEAPAEVQSLPAEE 689
+ PP E P+ + PPP + A A + P P AP +Q PP+ ++ +
Sbjct: 530 LTTPPLENLPS-LAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIA 588
Query: 690 TPIEETLAAVHSPPADDVPAEEASVDKHSPPADLLLTEEFPIGEASAEVSPPPSEQTPED 749
TP + A+ SPP +P SPP L T P +A ++ PP + P
Sbjct: 589 TPPPQAPPALASPPLQGLP---------SPPLSPLAT---PPPQAPPXLALPPLQAPPSP 636
Query: 750 EALVENVSTEFQSPQVAGIPAVKL 773
A SPQ AV L
Sbjct: 637 PASPPLSPLATPSPQAPNALAVHL 660
Score = 85.5 bits (210), Expect = 2e-16
Identities = 115/473 (24%), Positives = 158/473 (33%), Gaps = 63/473 (13%)
Query: 285 PAEETHVQVQPSTEETPDAEAATAVAENSVKVQPPPAEEAPLVEFPAEIQPPSAEESPSV 344
P ET + P + +TP A T EN + PPP + A A + P E
Sbjct: 510 PPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTAS-----APLTTPHLET---- 560
Query: 345 ELLAEILPPSAEESPSEEPPAEILPPPAEKSPSVELLGEIRSPSAQKAPIEVQPLPAEGA 404
PP P + PP+ + PP E S+ P+ P++ P P
Sbjct: 561 -------PPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSP---- 609
Query: 405 LEEAPAKVEPPTVEETLADVQPLLPEEAPREEARELQLSTAMETPAEEAPTEFQSPLPKE 464
+P PP LA L P +AP LS + TP+ +AP L +
Sbjct: 610 -PLSPLATPPPQAPPXLA----LPPLQAPPSPPASPPLS-PLATPSPQAPNALAVHLLQA 663
Query: 465 TTAEEASAEIQLLAATEPPADETPAEARSPLSE--ETSAEEAHAEVQSPLAEETTAEEAS 522
+ S +Q A PPA + + +P S+ + A SP A + A+
Sbjct: 664 PFSPPPSPPVQ--APFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSAT 721
Query: 523 AEIQLLAAIEAPADETPAE--AQSPLSEETSAEE------APAEVQSPSAKGVSIEEAPL 574
Q + AP + P A P+S + A +Q P + S+ +PL
Sbjct: 722 PPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPL 781
Query: 575 ELQPPSGEETTAEEASAAIQLLAATEASAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEV 634
PP A A+ A+ P + A Q PP AP
Sbjct: 782 AKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQ 841
Query: 635 QPPPAEEAPAEVQP--PPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQSLPAEETPI 692
PP +P P PP V P A A PPP +P+ S P
Sbjct: 842 VPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPD----- 896
Query: 693 EETLAAVHSPPADDVPAEEASVDKHSPPADLLLTEEFPIGEASAEVSPPPSEQ 745
A HS A P E D S P E A SPPP +
Sbjct: 897 ----LAGHSSSATSTPEELRGYD--SGP------------EGGAAASPPPDAE 931
Score = 64.3 bits (155), Expect = 4e-10
Identities = 99/418 (23%), Positives = 151/418 (36%), Gaps = 71/418 (16%)
Query: 354 SAEESPSEEPPA----EILPPPAEKSPSVELLGEIRSPSAQKAPIEVQPLPAEGALEEAP 409
++ +P+ PPA E PP SP G + SP PL +G A
Sbjct: 85 TSSRNPASRPPASGRGERAPPAKNTSP-----GPVSSPGRASGTTRPGPLGQKGLRISA- 138
Query: 410 AKVEPPTVEETLADVQPLLPEEAPREEARELQLSTAMETPAEEAPTEFQSPLPKETTAEE 469
EET+A + EAP+ A P P+ + + E
Sbjct: 139 --------EETVARGKAT---EAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEV 187
Query: 470 ASAEIQLLAATEPPADETPAEARSPLSEETSAEEAHAEVQSPLAEETTAEEASAEIQLLA 529
A PP E P ++ S SE ++ E + A + P A
Sbjct: 188 GLPRPAPSARPRPPT-EGPRKSVSSASEHSTTEPSPAARRRPSAG--------------G 232
Query: 530 AIEAPADETPAEAQSPLSEETSAEEAPAEVQSPSAKGVSIEEAPLELQPPSGEETTAEEA 589
++ PA + + + +PLS SP+ G S P PS + +A
Sbjct: 233 GLQRPASRSLSSSATPLS-------------SPARSGPSARGTPRAPAHPSQPKPKGLQA 279
Query: 590 SAAIQLLAATEASAEEAPAEVQPPPAEEAP----AEVQPPP---AEEAPAEVQPPPAEEA 642
Q+ + +A P A +P A PPP A PA + P P
Sbjct: 280 LRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLAT 339
Query: 643 PAEVQPPPAEEAPAEVQ----PP--PAEEAPAEVQPPPAEEAPAEVQSLPAEETPIEETL 696
P + PP+ AP +Q PP P +AP + PP +AP +Q++P + P T
Sbjct: 340 PLPL-APPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPM-QAPPSLQTIPPIQVPHSLTS 397
Query: 697 AAVHSPPAD-DVPAEEASVDKHSPPADLLLTEEF----PIGEASAEVSPPPSEQTPED 749
++ +PP+ + + +A+ SP L T F P ++ SP TP D
Sbjct: 398 PSLQAPPSPLALSSLQATTSLGSP--TLQATHSFLTMSPRQTQASLTSPSRPASTPPD 453
Score = 55.1 bits (131), Expect = 3e-07
Identities = 98/441 (22%), Positives = 153/441 (34%), Gaps = 49/441 (11%)
Query: 192 ASEHPEFQPATNSNEEIGQKNISRTSFTQETKKGPPVLLEDELREEVTVPVVQEGSAVKK 251
A+ P+ PA S G + + + PP L L+ + P S +
Sbjct: 588 ATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLAT 647
Query: 252 VASAEIEPPSTEKFPAKIQPPLVEEATAKAEPRPAEETHVQVQPSTEETPDAEAATAVAE 311
+ + A PP A P PA V PS TP ++A ++A
Sbjct: 648 PSPQAPNALAVHLLQAPFSPPPSPPVQAPFSP-PASPP---VSPSA--TPPSQAPPSLAA 701
Query: 312 NSVKVQPPPAEEAPLVEFPAEIQPPSAEESPSVELLAEILPPSAEESPSEEPPAEILPPP 371
++V P P P+ P+ PP A + L +PPS P PP P
Sbjct: 702 PPLQVPPSPPASPPMS--PSATPPPQAPPPLAAPPLQ--VPPS----PPASPPMSPSATP 753
Query: 372 AEKSPSVELLGEIRSPSAQKAPIEVQPLPAEGALEEAPAKVEPPTVEETLADVQPLLPEE 431
+ P + ++ P + A + + PL A+ + PA PP + L P +
Sbjct: 754 PPRVPPLLAAPPLQVPPSPPASLPMSPL-AKPPPQAPPALATPPL--QALPSPPASFPGQ 810
Query: 432 APREEARELQLSTAMETPAEEAPTEFQSPLPKETTAEEASAEIQLLAATEPPADET---- 487
AP + L +S + TP +AP +PL + + AS +Q P +T
Sbjct: 811 APFSPSASLPMS-PLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSG 869
Query: 488 ------------PAEARSPLSEETSAEEA-HAEVQSPLAEETTAEEASAEIQLLAAIEAP 534
P +RSP S + + A H+ + EE ++ E
Sbjct: 870 PRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPE-------GGA 922
Query: 535 ADETPAEAQSPLSEETSAEEAPAEVQSPSAKGVSIEEAPLELQPPSGEETTAEEASAAIQ 594
A P +A+ + PA P APL P +G + + I
Sbjct: 923 AASPPPDAELAACHPAAWSRGPA----PPLAFRGAPGAPLPWPPATGPGSA--DGLCTIY 976
Query: 595 LLAATEASAEEAPAEVQPPPA 615
E SA AP + P P+
Sbjct: 977 ETEGPE-SATPAPGALDPGPS 996
>gi|153945728 microtubule-associated protein 1B [Homo sapiens]
Length = 2468
Score = 94.4 bits (233), Expect = 4e-19
Identities = 200/903 (22%), Positives = 355/903 (39%), Gaps = 118/903 (13%)
Query: 3 GKSQQTDVIE---KKKHMAI---PKSSSPKATHRIGN--TSGSKGSYSAKAYESIRVSSE 54
G S Q +++E K KH+ P ++ T ++ +K A + ES++ +++
Sbjct: 491 GNSTQYNILEGLEKLKHLDFLKQPLATQKDLTGQVPTPVVKQTKLKQRADSRESLKPAAK 550
Query: 55 LQQTWTKRKHGQEMTSKSLQTDTIVEEKKEVKLVEETVVPEEKSADVREAAIELPESVQD 114
+ + RK +E T + + + VE+ +V+ E+ +V ++K E SV +
Sbjct: 551 PLPSKSVRKESKEETPEVTKVNH-VEKPPKVESKEKVMVKKDKPIKT-----ETKPSVTE 604
Query: 115 VEIPPNIPSVQLKMDRSQQTSRTGYWTMMNIPPVEKVDKEQQTYFSESEIVVISRPDSSS 174
E+P +K + +++ + V+ +++T E+++ + +
Sbjct: 605 KEVPSKEEPSPVKAEVAEKQATD----------VKPKAAKEKTVKKETKVKPEDKKEEKE 654
Query: 175 TKSKEDALKHKSSGKIFASEHPEFQPATNSNEEIGQKNISRTSFTQETKKGPPVLLEDEL 234
K K++ K + I E P+ + ++ +K + + K+ PP ++ E+
Sbjct: 655 -KPKKEVAKKEDKTPIKKEEKPKKEEVKKEVKKEIKKEEKKEPKKEVKKETPPKEVKKEV 713
Query: 235 REEVTVPVVQEGSAVKKV-------ASAEIEPPSTEKFPAKIQP--PLVEEATAK---AE 282
++E V +E KK A P S K PA ++P P EE+ K A
Sbjct: 714 KKEEKKEVKKEEKEPKKEIKKLPKDAKKSSTPLSEAKKPAALKPKVPKKEESVKKDSVAA 773
Query: 283 PRPAEETHVQVQPSTEETPDAEAA---TAVAENSVKVQPPPAEEAPLVEFPAEIQPPSAE 339
+P E+ ++V + +A AA T +V A P E AE S+
Sbjct: 774 GKPKEKGKIKVIKKEGKAAEAVAAAVGTGATTAAVMAAAGIAAIGPAKELEAERSLMSSP 833
Query: 340 ESPSVELLAEILPPSAEESPSEEPPAEILPPPAE--KSPSVELLGEIRSPSAQKAPIE-- 395
E + + E+ + + +P E++ + ++ VE + K P E
Sbjct: 834 EDLTKDF-EELKAEEVDVTKDIKPQLELIEDEEKLKETEPVEAYVIQKEREVTKGPAESP 892
Query: 396 ---VQPLPAEGALEEAPAKVEPPTVEETLADVQPLLPEEAPREEAREL-QLSTAMETPAE 451
+ EG E+ P ++EP ++ + D++ E A EE+ E ET
Sbjct: 893 DEGITTTEGEGECEQTPEELEP-VEKQGVDDIEKFEDEGAGFEESSETGDYEEKAETEEA 951
Query: 452 EAPTEF-----------QSPLPKETTAE-EASAEI----QLLAATEPPADETPAEARSPL 495
E P E SP E +A+ EA A I + +A+ + A+E EA
Sbjct: 952 EEPEEDGEEHVCVSASKHSPTEDEESAKAEADAYIREKRESVASGDDRAEEDMDEAIEKG 1011
Query: 496 SEETSAEEAHAEVQSPLA--EETTAEEASAEIQLLAAIEAPADETPAEAQ--------SP 545
E S EEA E ++ A EE E+ AE ++A ++ A+ AE Q
Sbjct: 1012 EAEQSEEEADEEDKAEDAREEEYEPEKMEAEDYVMAVVDKAAEAGGAEEQYGFLTTPTKQ 1071
Query: 546 LSEETSAEEAPAEVQSPSAKGVSIEEAPLELQPPSGEETTAEEASAAIQLLAAT-EASAE 604
L ++ E + + + G S EA + E EE +A +T E S+E
Sbjct: 1072 LGAQSPGREPASSIHDETLPGGSESEATASDE--ENREDQPEEFTATSGYTQSTIEISSE 1129
Query: 605 EAPAEVQPPP----AEEAPAEVQPPPAEE-----------------APAEVQPPPAEEAP 643
P + P ++E E P++E PA+V P
Sbjct: 1130 PTPMDEMSTPRDVMSDETNNEETESPSQEFVNITKYESSLYSQEYSKPADVTPLNGFSEG 1189
Query: 644 AEVQPPPAEEAPAE---VQPPPAEEAPAEVQPPPAEEAPAEVQSLPAEETPIEETLAAVH 700
++ ++ A + PP + E + + +EV++ + I+++++AV
Sbjct: 1190 SKTDATDGKDYNASASTISPPSSMEEDKFSRSALRDAYCSEVKA--STTLDIKDSISAVS 1247
Query: 701 SPPADDVPAEEASVDKHSPPADLLLTEEFPIGEASAEVSPPPSEQTPEDEALVENVSTEF 760
S P++ S+ SPP+ L E+ P+GE S S P+E EA V VS E
Sbjct: 1248 SEKVS--PSKSPSLSP-SPPSPL---EKTPLGERSVNFSLTPNEIKVSAEAEVAPVSPEV 1301
Query: 761 QSPQVAGIPAVKLGSVVLEGEAKFEEVSKINSVLKDLSNTNDGQAPTLEIESVFHIELKQ 820
V A + E VS SV +T Q+PT E S E+ +
Sbjct: 1302 TQEVVEEHCASP-------EDKTLEVVSPSQSVTGSAGHTPYYQSPTDEKSSHLPTEVIE 1354
Query: 821 RPP 823
+PP
Sbjct: 1355 KPP 1357
Score = 76.3 bits (186), Expect = 1e-13
Identities = 159/803 (19%), Positives = 292/803 (36%), Gaps = 72/803 (8%)
Query: 2 VGKSQQTDVIEKKKHMAIPKSSSPKATHRIGNTSGSKGSYSAKAYESIRVSSELQQTWTK 61
V K + +KK+ PK K + K E + + ++ K
Sbjct: 638 VKKETKVKPEDKKEEKEKPKKEVAKKEDKTPIKKEEKPKKEEVKKEVKKEIKKEEKKEPK 697
Query: 62 RKHGQEMTSKSLQTDTIVEEKKEVKLVEETVVPEEKSA--DVREAAIELPESVQDVEIPP 119
++ +E K ++ + EEKKEVK E+ E K D ++++ L E+ + + P
Sbjct: 698 KEVKKETPPKEVKKEVKKEEKKEVKKEEKEPKKEIKKLPKDAKKSSTPLSEAKKPAALKP 757
Query: 120 NIPSVQLKMDRSQQTSRTGYWTMMNIPPVEKVDKEQQTYFSESEIVVISRPDSSSTKSKE 179
+P K + S + ++ + KE + +E+ + +++
Sbjct: 758 KVP----KKEESVKKDSVAAGKPKEKGKIKVIKKEGKA--AEAVAAAVGTGATTAAVMAA 811
Query: 180 DALKHKSSGKIFASEHPEFQPATNSNEEIGQKNISRTSFTQETKKGPPV-LLEDELREEV 238
+ K +E + ++ + T++ K P + L+EDE + +
Sbjct: 812 AGIAAIGPAKELEAERSLMSSPEDLTKDFEELKAEEVDVTKDIK--PQLELIEDEEKLKE 869
Query: 239 TVPVV-----QEGSAVKKVASAEIEPPST-------EKFPAKIQP----------PLVEE 276
T PV +E K A + E +T E+ P +++P +E
Sbjct: 870 TEPVEAYVIQKEREVTKGPAESPDEGITTTEGEGECEQTPEELEPVEKQGVDDIEKFEDE 929
Query: 277 ATAKAEPRPAEETHVQVQPSTEETPDAEAATAVAENSVKVQPPPAEEAPLVEFPAEIQPP 336
E + + + E P+ + V ++ K P EE+ E A I+
Sbjct: 930 GAGFEESSETGDYEEKAETEEAEEPEEDGEEHVCVSASKHSPTEDEESAKAEADAYIREK 989
Query: 337 SAEESPSVELLAEILPPSAEESPSEEPPAEILPPPAEKSPSVELLGEIRSPSAQKAPIEV 396
+ + E + + E+ +E+ E E+ + + E P +A V
Sbjct: 990 RESVASGDDRAEEDMDEAIEKGEAEQSEEEA----DEEDKAEDAREEEYEPEKMEAEDYV 1045
Query: 397 QPLPAEGALEEAPAKVEPPTVEETLADVQPLLPEEAPREEARELQLSTAMETPAEEAPTE 456
+ + A E A+ + + + P P + L E+ A + E
Sbjct: 1046 MAV-VDKAAEAGGAEEQYGFLTTPTKQLGAQSPGREPASSIHDETLPGGSESEATASDEE 1104
Query: 457 FQSPLPKETTAEEASAEIQLLAATEPPADETPAEARSPLSEETSAEEAHAEVQSPLAEET 516
+ P+E TA + + ++EP + + R +S+ET+ EE + Q +
Sbjct: 1105 NREDQPEEFTATSGYTQSTIEISSEPTPMDEMSTPRDVMSDETNNEETESPSQEFV--NI 1162
Query: 517 TAEEASAEIQLLAAIEAPADETPAEAQSPLSEETSAE----EAPAEVQSPSAKGVSIEEA 572
T E+S Q PAD TP S S+ + + A A SP + S+EE
Sbjct: 1163 TKYESSLYSQ---EYSKPADVTPLNGFSEGSKTDATDGKDYNASASTISPPS---SMEED 1216
Query: 573 PLELQPPSGEETTAEEASAAIQLLAATEASAEEAPAEVQPPPAEEAPAEVQPPPAEEAPA 632
+ +AS + + + A + E + + P +P P P E+ P
Sbjct: 1217 KFSRSALRDAYCSEVKASTTLDIKDSISAVSSEKVSPSKSPSLSPSP----PSPLEKTPL 1272
Query: 633 EVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQSLPAEETPI 692
+ P E++ AE A V P +E E P E+ EV S P++
Sbjct: 1273 GERSVNFSLTPNEIK-VSAEAEVAPVSPEVTQEVVEEHCASP-EDKTLEVVS-PSQSV-- 1327
Query: 693 EETLAAVHSP----PADDVPAEEASVDKHSPPADLLLTEEFPIGEASAEVS----PPPSE 744
T +A H+P P D+ + + PPA + F +A E P E
Sbjct: 1328 --TGSAGHTPYYQSPTDEKSSHLPTEVIEKPPA---VPVSFEFSDAKDENERASVSPMDE 1382
Query: 745 QTPEDEALVENVSTEFQSPQVAG 767
P+ E+ +E V + +SP + G
Sbjct: 1383 PVPDSESPIEKVLSPLRSPPLIG 1405
Score = 65.1 bits (157), Expect = 3e-10
Identities = 155/735 (21%), Positives = 275/735 (37%), Gaps = 79/735 (10%)
Query: 28 THRIGNTSGSKGSYSAKAYESIRVSSELQQTWTKRKHGQ----EMTSKSLQTDTIVEEKK 83
T ++G S + S+ E++ SE + T + ++ + E T+ S T + +E
Sbjct: 1069 TKQLGAQSPGREPASSIHDETLPGGSESEATASDEENREDQPEEFTATSGYTQSTIEISS 1128
Query: 84 EVKLVEETVVPEEKSADVREAAIELPESVQDVEIPPNIPSVQLKMDRSQQTSRTGYWTMM 143
E ++E P + +D E E ES + NI + + SQ+ S+ T +
Sbjct: 1129 EPTPMDEMSTPRDVMSD--ETNNEETESPSQEFV--NITKYESSL-YSQEYSKPADVTPL 1183
Query: 144 N-IPPVEKVDKEQQTYFSESEIVVISRPDSSSTKSKEDALKHKSSGKIFASEHPEFQPAT 202
N K D ++ S + K AL+ ++ AS + + +
Sbjct: 1184 NGFSEGSKTDATDGKDYNASASTISPPSSMEEDKFSRSALRDAYCSEVKASTTLDIKDSI 1243
Query: 203 NSNEEIGQKNISRTSFTQETKKGPPVLLEDELREEVTVPVVQEGSAVKKVASAEIEPPST 262
++ + + +S S + PP LE E +V + +K A AE+ P S
Sbjct: 1244 SA---VSSEKVS-PSKSPSLSPSPPSPLEKTPLGERSVNFSLTPNEIKVSAEAEVAPVSP 1299
Query: 263 EKFPAKIQPPLVEEATAKAEPRPAEETHVQVQPSTEETPDAEAATAVAENSVKVQPPPAE 322
E + +VEE A P ++T V PS ++ T A ++ Q P E
Sbjct: 1300 E-----VTQEVVEEHCAS----PEDKTLEVVSPS-------QSVTGSAGHTPYYQSPTDE 1343
Query: 323 EAPLVEFPAEIQPPSAEESPSVELLAEILPPSAEESPSEEPPAEILPPPAEKSPSVELLG 382
++ P E+ E+ P+V + E E + P + P P +SP ++L
Sbjct: 1344 KSS--HLPTEV----IEKPPAVPVSFEFSDAKDENERASVSPMDE-PVPDSESPIEKVLS 1396
Query: 383 EIRSP----------SAQKAPIEVQPLPAEGALEEAPAKVEPPTVEETLADVQPLLPEEA 432
+RSP S A + AE EE K P ++++ +
Sbjct: 1397 PLRSPPLIGSESAYESFLSADDKASGRGAESPFEEKSGKQGSPDQVSPVSEMTSTSLYQ- 1455
Query: 433 PREEARELQLSTAMETPAEEAPT---EFQSPLPKETTAEEASAEIQLLAATEPPADETPA 489
++E + + E +E T E S P E ++
Sbjct: 1456 DKQEGKSTDFAPIKEDFGQEKKTDDVEAMSSQPALALDERKLGDVSPTQIDVSQFGSFKE 1515
Query: 490 EARSPLSEETSAEEAHAEVQSPLAEET------TAEEASAEIQLLAAIEAPADETP---- 539
+ + +SE T ++++ V +AE+T A ++A + + E D+
Sbjct: 1516 DTKMSISEGTVSDKSATPVDEGVAEDTYSHMEGVASVSTASVATSSFPEPTTDDVSPSLH 1575
Query: 540 AEAQSPLSEETSAEEAPAEVQSPSA-----KGVSIEEAP--LELQPPSGEETTAEEASAA 592
AE SP S E + + VQ+P+ S EE P + + PP TA+ +
Sbjct: 1576 AEVGSPHSTEVDDSLSVSVVQTPTTFQETEMSPSKEECPRPMSISPPDFSPKTAKSRTP- 1634
Query: 593 IQLLAATEASAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAE 652
+Q + ++S + P + Q P A V E P EV P++
Sbjct: 1635 VQDHRSEQSSMSIEFGQESPEQSLAMDFSRQSPDHPTVGAGVLHI-TENGPTEVDYSPSD 1693
Query: 653 EAPAEVQP--PPAEEAPAEVQPPPAEEAPAEVQSLPAEETPIEETLAAVHSPPADDVPAE 710
+ + PP EE P+ Q E + Q E +P + ++ H+P P +
Sbjct: 1694 MQDSSLSHKIPPMEE-PSYTQDNDLSELISVSQ---VEASP---STSSAHTPSQIASPLQ 1746
Query: 711 EASVDKHSPPADLLL 725
E ++ +PP D+ L
Sbjct: 1747 EDTLSDVAPPRDMSL 1761
Score = 47.0 bits (110), Expect = 7e-05
Identities = 107/500 (21%), Positives = 183/500 (36%), Gaps = 46/500 (9%)
Query: 103 EAAIELPESVQDVEIPPNIPSVQLKMDRSQQTSRTGYWTMMNIPPVEKVDKEQQTYFSES 162
E + LP V +E PP +P D + R M P + E+ S
Sbjct: 1343 EKSSHLPTEV--IEKPPAVPVSFEFSDAKDENERASVSPMDEPVPDSESPIEKVLSPLRS 1400
Query: 163 EIVVISRPDSSSTKSKEDALKHKSSGKIFASEHPEFQPATNSNEEIGQ-KNISRTSFTQE 221
++ S S S +D K+SG+ S E S +++ ++ TS Q+
Sbjct: 1401 PPLIGSESAYESFLSADD----KASGRGAESPFEEKSGKQGSPDQVSPVSEMTSTSLYQD 1456
Query: 222 TKKGPPV----LLEDELREEVTVPVVQEGSA---------VKKVASAEIEPPSTEKFPAK 268
++G + ED +E+ T V S + V+ +I+ F
Sbjct: 1457 KQEGKSTDFAPIKEDFGQEKKTDDVEAMSSQPALALDERKLGDVSPTQIDVSQFGSFKED 1516
Query: 269 IQPPLVEEATAKAEPRPAEETHVQVQPSTEETPDAEAATAVAENSVKVQPPPAEEAPLVE 328
+ + E + P +E V T + A+ + A + P P +
Sbjct: 1517 TKMSISEGTVSDKSATPVDEG---VAEDTYSHMEGVASVSTASVATSSFPEPTTDDVSPS 1573
Query: 329 FPAEIQPPSAEESPSVELLAEILPPSAEESPSEEPPAEILPPPAEKSPSVELLGEIRSPS 388
AE+ P + E ++ + P+ + P E P P SP SP
Sbjct: 1574 LHAEVGSPHSTEVDDSLSVSVVQTPTTFQETEMSPSKEECPRPMSISPPDF------SPK 1627
Query: 389 AQKAPIEVQPLPAEGALEEAPAKVEPPTVEETLADVQPLLPEEAPREEARELQLSTAMET 448
K+ VQ +E + E P E++LA + P A L ++ T
Sbjct: 1628 TAKSRTPVQDHRSEQSSMSIEFGQESP--EQSLAMDFSRQSPDHPTVGAGVLHITENGPT 1685
Query: 449 PAEEAPTEFQS--------PL--PKETTAEEASAEI---QLLAATEPPADETPAEARSPL 495
+ +P++ Q P+ P T + S I Q+ A+ + TP++ SPL
Sbjct: 1686 EVDYSPSDMQDSSLSHKIPPMEEPSYTQDNDLSELISVSQVEASPSTSSAHTPSQIASPL 1745
Query: 496 SEETSAEEAHAEVQSPLAEETTAEEASAEIQLLAAIEAPADETPAEAQSPLSEETSAEEA 555
E+T ++ A S A T+ + S E + L+ + TP E+ SPL T ++
Sbjct: 1746 QEDTLSDVAPPRDMSLYASLTSEKVQSLEGEKLSPKSDISPLTPRES-SPLYSPTFSDST 1804
Query: 556 PAEVQSPSAKGVSIEEAPLE 575
A V+ +A S P++
Sbjct: 1805 SA-VKEKTATCHSSSSPPID 1823
Score = 45.1 bits (105), Expect = 3e-04
Identities = 138/733 (18%), Positives = 263/733 (35%), Gaps = 86/733 (11%)
Query: 66 QEMTSKSLQTDTIVEEKK---EVKLVEETVVPEEKSADVREAAI---ELPESVQDVEIPP 119
+E T S+ T+ ++ + + E+T E A V A++ PE D ++ P
Sbjct: 1514 KEDTKMSISEGTVSDKSATPVDEGVAEDTYSHMEGVASVSTASVATSSFPEPTTD-DVSP 1572
Query: 120 NIPSVQLKMDRSQQTSRTGYWTMMNIPPVEKVDKEQQTYFSESEI-----VVISRPDSSS 174
++ + ++ S + + +++ V+ Q+T S S+ + IS PD S
Sbjct: 1573 SLHA-EVGSPHSTEVDDS-----LSVSVVQTPTTFQETEMSPSKEECPRPMSISPPDFSP 1626
Query: 175 TKSK-----EDALKHKSSGKI-FASEHPEFQPATNSNEEIGQKNISRTSFTQETKKGP-- 226
+K +D +SS I F E PE A + + + T+ GP
Sbjct: 1627 KTAKSRTPVQDHRSEQSSMSIEFGQESPEQSLAMDFSRQSPDHPTVGAGVLHITENGPTE 1686
Query: 227 ----PVLLEDELREEVTVPV-----VQEGSAVKKVASAEIEP-PSTEKF--PAKIQPPLV 274
P ++D P+ Q+ + ++ +++E PST P++I PL
Sbjct: 1687 VDYSPSDMQDSSLSHKIPPMEEPSYTQDNDLSELISVSQVEASPSTSSAHTPSQIASPLQ 1746
Query: 275 EEATAKAEPRPAEETHVQVQPSTEETPDAEAATAVAENSVKVQPPPAEEAPLVEFPAEIQ 334
E+ + P + + ++ + E + ++ S P E +PL P
Sbjct: 1747 EDTLSDVAPPRDMSLYASLTSEKVQSLEGEKLSPKSDISPLT---PRESSPLYS-PTFSD 1802
Query: 335 PPSAEESPSVELLAEILPPSAEESPSEEP---PAEILPPPAEKSPSVELLGEIRSPSAQK 391
SA + + + PP ++ S EP A +L + + L ++ +P +K
Sbjct: 1803 STSAVKEKTATCHSSSSPPI--DAASAEPYGFRASVLFDTMQHH--LALNRDLSTPGLEK 1858
Query: 392 APIEVQPLPAEGALEEAPAKVEPPTVEE----------TLADVQPLLPEEAPREEARELQ 441
P A ++ P E+ +DV E+ R
Sbjct: 1859 DSGGKTPGDFSYAYQKPEETTRSPDEEDYDYESYEKTTRTSDVGGYYYEKIERTTKSPSD 1918
Query: 442 LSTAMETPAEEAPT----EFQSPLPKETTA--EEASAEIQLLAATEPPAD------ETPA 489
+ ET + T ++ + ++TT EE + T P + E
Sbjct: 1919 SGYSYETIGKTTKTPEDGDYSYEIIEKTTRTPEEGGYSYDISEKTTSPPEVSGYSYEKTE 1978
Query: 490 EARSPLSEETSAEEAHAEVQSPLAEETTAEEASAEIQLLAAIEAPADETPAEA-QSPLSE 548
+R L + ++ + + L + + + E + +I E + ET + ++P +
Sbjct: 1979 RSRRLLDDISNGYDDSEDGGHTLGDPSYSYETTEKITSFPESEGYSYETSTKTTRTPDTS 2038
Query: 549 ETSAEEAPAEVQSPSAKGVSIEEAPLELQPPSGEETTAEEASAAIQLLAATEAS-----A 603
E A ++P A S E + L + E+ + EA + L +
Sbjct: 2039 TYCYETAEKITRTPQASTYSYETSDLCY---TAEKKSPSEARQDVDLCLVSSCEYKHPKT 2095
Query: 604 EEAPAEVQPPPAE----EAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQ 659
E +P+ + P P E E P E P ++ PP ++ + P
Sbjct: 2096 ELSPSFINPNPLEWFASEEPTEESEKPLTQSGGAPPPPGGKQQGRQCDETPPTSVSESAP 2155
Query: 660 PPPAEEAPAEVQPPPAEEAPAEVQSLPAEET-PIEETLAAVHSPPADDVPAEEASVDKHS 718
+ P E + P+ A A + S ET P ++T+ H P P ++ S
Sbjct: 2156 SQTDSDVPPETEECPSITADANIDSEDESETIPTDKTVTYKHMDP-PPAPVQDRSPSPRH 2214
Query: 719 PPADLLLTEEFPI 731
P ++ E I
Sbjct: 2215 PDVSMVDPEALAI 2227
Score = 42.0 bits (97), Expect = 0.002
Identities = 100/505 (19%), Positives = 183/505 (36%), Gaps = 61/505 (12%)
Query: 281 AEPRPAEETHVQVQPSTEETPDAEAATAVAE--NSVKVQPP--------PAEEAPLVEFP 330
+EP P +E ++ET + E + E N K + PA+ PL F
Sbjct: 1128 SEPTPMDEMSTPRDVMSDETNNEETESPSQEFVNITKYESSLYSQEYSKPADVTPLNGFS 1187
Query: 331 AEIQPPSAEESPSVELLAEILPPSA--EESPSEEPPAEILPPPAEKSPSVELLGEIRSPS 388
+ + + + I PPS+ E+ S + + S ++++ I + S
Sbjct: 1188 EGSKTDATDGKDYNASASTISPPSSMEEDKFSRSALRDAYCSEVKASTTLDIKDSISAVS 1247
Query: 389 AQKAPIEVQPLPAEGALEEAPAKVEPPTVEETLADVQPLLPEEAPREEARELQLSTAMET 448
++K V P + P+ +E + E + L P E +
Sbjct: 1248 SEK----VSPSKSPSLSPSPPSPLEKTPLGERSVNFS-LTPNEIK------------VSA 1290
Query: 449 PAEEAPTEFQSPLPKETTAEE--ASAEIQLLAATEPPADETPAEARSPL----SEETSAE 502
AE AP SP + EE AS E + L P T + +P ++E S+
Sbjct: 1291 EAEVAPV---SPEVTQEVVEEHCASPEDKTLEVVSPSQSVTGSAGHTPYYQSPTDEKSSH 1347
Query: 503 EAHAEVQSPLAEETTAEEASAEIQLLAAIEAPADETPAEAQSPLSEETSAEEAPAEVQSP 562
++ P A + E + A+ + A +P DE +++SP+ + S +P + S
Sbjct: 1348 LPTEVIEKPPAVPVSFEFSDAKDENERASVSPMDEPVPDSESPIEKVLSPLRSPPLIGSE 1407
Query: 563 SA--------KGVSIEEAPLELQPPSGEETTAEEASAAIQLLAATEASAEEAPAEVQPPP 614
SA S A + SG++ + ++ S ++ + + ++ P
Sbjct: 1408 SAYESFLSADDKASGRGAESPFEEKSGKQGSPDQVSPVSEMTSTSLYQDKQEGKSTDFAP 1467
Query: 615 ------AEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPA 668
E+ +V+ ++ A A + + +P ++ + + +E +
Sbjct: 1468 IKEDFGQEKKTDDVEAMSSQPALALDERKLGDVSPTQIDVSQFGSFKEDTKMSISEGTVS 1527
Query: 669 EVQPPPAEEAPAEVQSLPAEETPIEETLAAVHS----PPADDV-PAEEASV-DKHSPPAD 722
+ P +E AE E T + S P DDV P+ A V HS D
Sbjct: 1528 DKSATPVDEGVAEDTYSHMEGVASVSTASVATSSFPEPTTDDVSPSLHAEVGSPHSTEVD 1587
Query: 723 LLLT---EEFPIGEASAEVSPPPSE 744
L+ + P E+SP E
Sbjct: 1588 DSLSVSVVQTPTTFQETEMSPSKEE 1612
Score = 35.4 bits (80), Expect = 0.22
Identities = 83/378 (21%), Positives = 130/378 (34%), Gaps = 76/378 (20%)
Query: 252 VASAEIEPPSTEKFPAKIQP-PLV----EEATAKAEPRPAEETHVQVQPS-------TEE 299
V+S E + P TE P+ I P PL EE T ++E + P +E
Sbjct: 2085 VSSCEYKHPKTELSPSFINPNPLEWFASEEPTEESEKPLTQSGGAPPPPGGKQQGRQCDE 2144
Query: 300 TPDAEAATAVAENSVKVQPPPAEEAPLVEFPAEIQPPSAEESPSVELLAEILPPSAEESP 359
TP + + + PP EE P + A I S +ES ++ +
Sbjct: 2145 TPPTSVSESAPSQTDSDVPPETEECPSITADANID--SEDESETIP-----TDKTVTYKH 2197
Query: 360 SEEPPAEILPPPAEKSPSVELLGEIRSPSAQKAPIEVQPLPAEGALEEAPAKVEPPTVEE 419
+ PPA + + RSPS + + + V+P E
Sbjct: 2198 MDPPPAPV---------------QDRSPSPRHPDVSM---------------VDP----E 2223
Query: 420 TLADVQPLLPEEAPREEARELQLSTAMETPAEEAPTEFQSPLPKETTAEEASAEIQLLAA 479
LA Q L +A + L +T T+ SP+ K + A A
Sbjct: 2224 ALAIEQNL-------GKALKKDLKEKTKTKKPGTKTKSSSPVKKSDGKSKPLAASPKPAG 2276
Query: 480 TEPPADETPAEARSPLSEETSAEEAHAEVQSPLAEETTAEEASAEIQLLAAIEAPADETP 539
+ +D+ + SP +E S E+A +P + EE E + A A
Sbjct: 2277 LKESSDKV-SRVASPKKKE-SVEKAAKPTTTPEVKAARGEEKDKETKNAANASASKSAKT 2334
Query: 540 AEAQSPLSEETSAEEAPAEV----------QSPSAKGVSIE---EAPLELQPPSGEETTA 586
A A ++ T + P + ++K V +E SG + A
Sbjct: 2335 ATAGPGTTKTTKSSAVPPGLPVYLDLCYIPNHSNSKNVDVEFFKRVRSSYYVVSGNDPAA 2394
Query: 587 EEASAAIQLLAATEASAE 604
EE S A+ L A E A+
Sbjct: 2395 EEPSRAV-LDALLEGKAQ 2411
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 85.9 bits (211), Expect = 1e-16
Identities = 167/814 (20%), Positives = 296/814 (36%), Gaps = 86/814 (10%)
Query: 38 KGSYSAKAYES--IRVSSELQQTWTKRKHG---------QEMTSKSLQTDTIVEEKKEVK 86
KGS A ES + EL + ++ G Q SKS TDT E+K
Sbjct: 68 KGSVPPAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSEQKLPG 127
Query: 87 LVEETV-VPEEKS-ADVREA--AIELPESVQDVEIPPNIPSVQLKMDRSQQTSRTGYWTM 142
T+ + E KS D++E + +P + +V + SV K + S +
Sbjct: 128 RSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEASQE 187
Query: 143 MNIPPVEKVDKEQQTYFSESEIVVISRPDSSSTKSK---EDALKHKSSGKIFASEHPEFQ 199
+ V KEQ + + +P K + D L+ + K +S+ PE
Sbjct: 188 ETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPE-- 245
Query: 200 PATNSNEEIGQKNISRTSFTQETKKGPPVLLEDELREEVTVPVVQEGSAVKKVASAEIEP 259
S K I + T +T L D R + + G +VK + +P
Sbjct: 246 -KIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKP 304
Query: 260 PSTEKFPAKIQPPLVEEATAKAEPRPAEETHVQVQPSTEETPDAEAATAVAENSVKVQPP 319
P + P K PP + K++P PA+ QPS P A+ V VQPP
Sbjct: 305 PIQQPTPGK--PPAQQPGHEKSQPGPAKPP---AQPSGLTKPLAQQPGTVKP---PVQPP 356
Query: 320 -----PAEEAPLVEFPAE---IQPPSAEESPSVELLAEILPPSAEESPSEEP-----PAE 366
PA+ + PA+ + PS+E+ P + LA+ PP ++P+++P P +
Sbjct: 357 GTTKPPAQPLGPAKPPAQQTGSEKPSSEQ-PGPKALAQ--PPGVGKTPAQQPGPAKPPTQ 413
Query: 367 ILPPPAEKSPSVELLGEIRSPSAQKAPIEVQPLPAEGALEEA------------------ 408
+ P + L ++P K P++ QP P + ++A
Sbjct: 414 QVGTPKPLAQQPGLQSPAKAPGPTKTPVQ-QPGPGKIPAQQAGPGKTSAQQTGPTKPPSQ 472
Query: 409 -PAKVEPPTVEETLADVQPLLPEEAPREEARELQLSTAMETPAEEAPTEFQSPLPKETTA 467
P +PP + A P P A + + P P+ Q K +
Sbjct: 473 LPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQ 532
Query: 468 EEASAEIQLLAATEPPADETPAEARSPLSEETSAEEAHAEVQSPLAEETTAEEASAEIQL 527
+ SA+ A PA + ++ P+S+ S + SP A++ ++ I
Sbjct: 533 QPGSAKPS--AQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICP 590
Query: 528 LAAIEAPADETPAEAQSPLSEETSAEEAPAEVQSPSAKGVSIEE---APLELQPPSGEET 584
L P +A E +P+ ++E +++ G +
Sbjct: 591 LCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDL 650
Query: 585 TAEEASAAIQLLAATEASAEEAPAEVQPPPAEEAPAEVQPPPAE--EAPAEVQPPPAEEA 642
+S +L A + A ++ P P + +P + P + +AP +PPP +
Sbjct: 651 APVPSSPQPKLKTAP-VTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQ 709
Query: 643 P-------AEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQSLPAEETPIEET 695
P A+ + PP ++ ++ PP P+E P + + + T + +
Sbjct: 710 PTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSS 769
Query: 696 LAAVHSPPADDVPAEEASVDKHSPPADLLLTEEFPIGEASAEVSPPPSEQTPEDEALVEN 755
+A P + + +K +PP L T+ + S P + +P D +
Sbjct: 770 SSATTKPDIPSSKVQSQAEEKTTPP---LKTDS---AKPSQSFPPTGEKVSPFDSKAIPR 823
Query: 756 VSTEFQSPQVAGIPAVKLGSVVLEGEAKFEEVSK 789
+++ + G + G ++ K EE K
Sbjct: 824 PASDSKIISHPGPSSESKGQKQVDPVQKKEEPKK 857
Score = 77.0 bits (188), Expect = 7e-14
Identities = 103/470 (21%), Positives = 176/470 (37%), Gaps = 82/470 (17%)
Query: 249 VKKVASAEIEP-PSTEKFPAKIQPPLVEEATAKAEPRPAEETHVQVQPSTEETPDAEAAT 307
+K+ ++ P PS+ + K P A +K+ P+P Q P + P + +
Sbjct: 642 MKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQ-----QTSPKKDAAPKQDLSK 696
Query: 308 AVAENSVKVQPPPAEEAPLVEFPAEIQPPSAE--ESPSVELLAEILPPSAEESPSEEPPA 365
A P P + PLV+ P PSA+ + P + L++ PP PSE+ A
Sbjct: 697 A---------PEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKA 747
Query: 366 EILPPPAEKSPSVELLGEIRSPSAQKAPIEVQPLPAEGALEEAPAKVEPPTVEETLADVQ 425
+ ++ V+ ++ S S+ ++ P+ +A K PP ++ Q
Sbjct: 748 PVADDKPKQPKMVKPTTDLVSSSSATTKPDI---PSSKVQSQAEEKTTPPLKTDSAKPSQ 804
Query: 426 PLLPEEAPREEARELQLSTAMETPAEEAPTEFQSPLPKETTAEEASAEIQLLAATEPPAD 485
P E+ S A+ PA ++ E+ ++ +Q
Sbjct: 805 SFPPTG---EKVSPFD-SKAIPRPASDSKIISHPGPSSESKGQKQVDPVQ--------KK 852
Query: 486 ETPAEARSPLSEETSAEEAHAEVQSPLAEETTAEEASAEIQLLAAIEAPADETPAEAQSP 545
E P +A++ +S + A+ +P TA + P QSP
Sbjct: 853 EEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQT----------------VPTPQQSP 896
Query: 546 LSEETSAEEAPAEVQSPSAKGVSIEEAPLELQPPSGEETTAEE-----ASAAIQLLAATE 600
+E S S SI +AP + QP + +ET + AS Q
Sbjct: 897 KPQEQSRRF--------SLNLGSITDAP-KSQPTTPQETVTGKLFGFGASIFSQASNLIS 947
Query: 601 ASAEEAPAEVQPP--PAEEAPAEVQPPPAEEAP---AEVQPPPAEEAP---------AEV 646
+ + P P P ++APA QPP ++ P + P PA+ P AE
Sbjct: 948 TAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEK 1007
Query: 647 QPPPAEEAP------AEVQPPPAEEAPAEVQPPPAEEAPAEVQSLPAEET 690
P AE+AP E +PPP +++ + P P +++ P E+
Sbjct: 1008 LEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPES 1057
Score = 70.5 bits (171), Expect = 6e-12
Identities = 124/573 (21%), Positives = 208/573 (36%), Gaps = 73/573 (12%)
Query: 241 PVVQEGSAVKKVASAEIEPPSTEKFPAKI--QPPLVEEATAKAEPRPAEETHVQV---QP 295
P G A E PS+E+ K QPP V + A+ +P PA+ QV +P
Sbjct: 362 PAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQ-QPGPAKPPTQQVGTPKP 420
Query: 296 STEETPDAEAATAVAENSVKVQPP-----PAEEA--------------PLVEFPAEIQPP 336
++ A A VQ P PA++A P + P +PP
Sbjct: 421 LAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPP 480
Query: 337 SAEESPSVELLAEILPPSAEESPSEEPPAEILPP--PAEKSPSVELLGEIRSPSAQKA-- 392
+ P+ + P + + PS++P + PP P PS + G + PS Q
Sbjct: 481 PQQPGPAKPPPQQ---PGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSA 537
Query: 393 -PIEVQPLPAEGALEEAPAKV---------EPPTVEETLADV--QPLLPEEAPREEAREL 440
P QP PA+ + +++ V +PPTV + Q L P EL
Sbjct: 538 KPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTEL 597
Query: 441 QLSTAMETPAEEAPTEFQS---------PLPKETTAEE-ASAEIQLLAATEPPADETPAE 490
L E TE Q+ P P T +E Q+ A P+
Sbjct: 598 LLHVP-EKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSS 656
Query: 491 ARSPLSEETSAEEAHAEVQSPLAEETTAEEASAEIQLLAAIEAPADETPAEAQSPLSEET 550
+ L + SP ++T+ ++ +A Q L+ P P Q L
Sbjct: 657 PQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSP 716
Query: 551 SAEEAPAEVQSPSAKGVSIEEAPLELQPPSGEETT--AEEASAAIQLLAATEASAEEAPA 608
SA+ Q P A +S P E PS ++ A++ +++ T + A
Sbjct: 717 SAKAK----QPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSA 772
Query: 609 EVQPP-PAEEAPAEVQ----PPPAEEA--PAEVQPPPAEEAP---AEVQPPPAEEAPAEV 658
+P P+ + ++ + PP ++ P++ PP E+ ++ P PA ++
Sbjct: 773 TTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIIS 832
Query: 659 QPPPAEEAPAE--VQPPPAEEAPAEVQSLPAEETPIEETLAAVHSPPADDVPAEEASVDK 716
P P+ E+ + V P +E P + Q+ + + + +PP A +
Sbjct: 833 HPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTP 892
Query: 717 HSPPADLLLTEEFPIGEASAEVSPPPSEQTPED 749
P + F + S +P TP++
Sbjct: 893 QQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQE 925
Score = 37.7 bits (86), Expect = 0.044
Identities = 87/489 (17%), Positives = 167/489 (34%), Gaps = 97/489 (19%)
Query: 47 ESIRVSSELQQTWTKRKHGQEMTS------KSLQTDTIVEEKKEVKLVEETVVPEEKSAD 100
E I+ S E ++ K+ Q++ S KS D I ++ VEE+ E
Sbjct: 1466 EEIKESQEERKDTFKKDSQQDIPSSKDHKEKSEFVDDITTRREPYDSVEESSESENSPVP 1525
Query: 101 VREAAIELPESVQDVEIPPNIPSVQLKMDRSQQTSRTGYWTMMNIPPVEKVDKEQQTYFS 160
R+ + S D + K + SQ + + I +E E +
Sbjct: 1526 QRKRRTSVGSSSSD----------EYKQEDSQGSGEEEDFIRKQI--IEMSADEDASGSE 1573
Query: 161 ESEIVVISRPDSSSTKSKEDALKHKSSGKIFASEHPEF--QPATNSNEEIGQKNISRTSF 218
+ E + + SS+ + + K GKI A +H + +T+ +E+ G+++
Sbjct: 1574 DDEFIRNQLKEISSSTESQKKEETKGKGKITAGKHRRLTRKSSTSIDEDAGRRHSWHDED 1633
Query: 219 TQETKKGPPVLLEDELREEVTVPVVQEGSAVKKVASAEIEPPSTEKFPAKIQPPLVEEAT 278
+ + P + + +E VV G +++ + E+ +K+ A E +
Sbjct: 1634 DEAFDESPELKYRETKSQESEELVVTGGGGLRRFKTIELNSTIADKYSA-------ESSQ 1686
Query: 279 AKAEPRPAEETHVQVQPSTEETPD---AEAATAVAENSVKVQPPPAEEAPLVEFPAEIQP 335
K EE ++++ T+ D E ++++ +S P + L E
Sbjct: 1687 KKTSLYFDEEPELEMESLTDSPEDRSRGEGSSSLHASSFTPGTSPTSVSSLDE------- 1739
Query: 336 PSAEESPSVELLAEILPPSAEESPSEEPPAEILPPPAEKSPSVELLGEIRSPSAQKAPIE 395
++ SPS + A P LL I S
Sbjct: 1740 ------------------DSDSSPSHKKGESKQQRKARHRPHGPLLPTIEDSSE------ 1775
Query: 396 VQPLPAEGALEEAPAKVEPPTVEETLADVQPLLPEEAPREEARELQLSTAMETPAEEAPT 455
EE L + + LL E+ + E + Q ++ + ++
Sbjct: 1776 ----------------------EEELREEEELLKEQEKQREIEQQQRKSSSKKSKKDK-- 1811
Query: 456 EFQSPLPKETTAEEASAEIQLLAATEPPADETPAEARSPLSEETSAEEAHAEVQSPLAEE 515
+E A+ + PP++ +P E SP E A E +S +E
Sbjct: 1812 ------------DELRAQRRRERPKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEY 1859
Query: 516 TTAEEASAE 524
+ + E+ E
Sbjct: 1860 SPSIESDPE 1868
Score = 36.2 bits (82), Expect = 0.13
Identities = 66/378 (17%), Positives = 128/378 (33%), Gaps = 49/378 (12%)
Query: 435 EEARELQLSTAMETPAEEAPTEFQSPLPKETTAE-EASAEIQLLAATEPPA---DETPAE 490
E++ E+ ST + P E L + + ASA+ +++ ++ + + +
Sbjct: 2221 EDSEEISSSTYFPGSIIDYPEEISVSLDRTAPPDGRASADHIVISLSDMASSIIESVVPK 2280
Query: 491 ARSPLSEETSAEEAHAEVQSPLAEETTAEEASAEIQLLAAIEAPADETPAEAQSPLSE-- 548
P+++ S + +E + P+ + A++ + +L +EA D+ EA+ S
Sbjct: 2281 PEGPVADTVSTDLLISE-KDPVKK---AKKETGNGIILEVLEAYRDKKELEAERTKSSLS 2336
Query: 549 ETSAEEAPAEVQSPSAKGVSIEEAPLELQPPSGEETTAEEASAAIQLLAATEAS------ 602
ET + P+ V + K + G+E A + + +++ A
Sbjct: 2337 ETVFDHPPSSVIALPMKE-QLSTTYFTSGETFGQEKPASQLPSGSPSVSSLPAKPRPFFR 2395
Query: 603 AEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPP 662
+ QPPP P PPP P + PPP P + A P
Sbjct: 2396 SSSLDISAQPPPPPPPPPPPPPPPPPPPPPPL-PPPTSPKPTILPKKKLTVASPVTTATP 2454
Query: 663 AEEAPAEVQ-------------------PPPAEEAPAEVQS------------LPAEETP 691
+A ++ PPP P+ + S P P
Sbjct: 2455 LFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKP 2514
Query: 692 IEETLAAVHSPPADDVPAEEASVDKHSPPADLLLTEEFPIGEASAEVSPPPSEQTPEDEA 751
+ L P D P S +L+ + ++ + ++ +SP ++ +P
Sbjct: 2515 VIPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLVTSADYKLPSPTSPLSPHSNKSSPRFSK 2574
Query: 752 LVENVSTEFQSPQVAGIP 769
+ P G P
Sbjct: 2575 SLTETYVVITLPSEPGTP 2592
Score = 34.7 bits (78), Expect = 0.37
Identities = 110/592 (18%), Positives = 189/592 (31%), Gaps = 150/592 (25%)
Query: 18 AIPKSSSPKATHRIGNTSGSKGSYSAKAYESIR-VSSELQQTWTKRKHGQEMTSKSLQTD 76
++P S +P T + + + S +SI V +E TK + +E++S +
Sbjct: 2175 SVPPSDTPSLTSSVSSVCTTDSSSPITTLDSITTVYTEPVDMITKFEDSEEISSSTYFPG 2234
Query: 77 TIVEEKKEVKLVEETVVPEEKSADVREAAIELPESVQDVEIPPNIPSVQLKMDRSQQTSR 136
+I++ +E+ + + P + A I L + + I SV K + +
Sbjct: 2235 SIIDYPEEISVSLDRTAPPDGRASADHIVISLSDMASSI-----IESVVPKPEGPVADTV 2289
Query: 137 TGYWTMMNIPPVEKVDKEQQTYFSESEIVVISRPDSSSTKSKEDALKHKSSGKIFASEHP 196
+ + PV+K KE +++ ++ K + +A + KSS +HP
Sbjct: 2290 STDLLISEKDPVKKAKKET------GNGIILEVLEAYRDKKELEAERTKSSLSETVFDHP 2343
Query: 197 EFQPATNSNEEIGQKNISRTSFTQETKKGPPVLLEDELREEVTVPVVQEGSAVKKVASAE 256
+E +S T FT G +E + GS
Sbjct: 2344 PSSVIALPMKE----QLSTTYFTSGETFG----------QEKPASQLPSGS--------- 2380
Query: 257 IEPPSTEKFPAKIQPPLVEEATAKAEPRPAEETHVQVQPSTEETPDAEAATAVAENSVKV 316
PS PAK PRP + + +
Sbjct: 2381 ---PSVSSLPAK--------------PRPFFRS--------------------SSLDISA 2403
Query: 317 QPPPAEEAPLVEFPAEIQPPSAEESPSVELLAEILPPSAEESPSEEPPAEILPPPAEKSP 376
QPPP PP PP P PP LPPP P
Sbjct: 2404 QPPPP-------------PP---------------PPPPPPPPPPPPPPPPLPPPTSPKP 2435
Query: 377 SV--ELLGEIRSPSAQKAP-------------IEVQPLPAEGALEEAPAKV--EPPTVEE 419
++ + + SP P + LP AP V +P ++
Sbjct: 2436 TILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPS 2495
Query: 420 TLADV---QPLLPEEAPREEARELQLSTAMETPAEEAPTEFQSPLPKETTAEEASAEIQL 476
L +P P AP+ +L +T T PT S T SA+ +L
Sbjct: 2496 GLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGL-SLTSSMTLNLVTSADYKL 2554
Query: 477 LAATEPPADET--------------------PAEARSPLSEETSAEEAHAEVQSPLAEET 516
+ T P + + P+E +P S + SP +
Sbjct: 2555 PSPTSPLSPHSNKSSPRFSKSLTETYVVITLPSEPGTPTDSSASQAITSWPLGSPSKDLV 2614
Query: 517 TAEEASAEIQLLAAIEAP--ADET-------PAEAQSPLSEETSAEEAPAEV 559
+ E + + + A+E P +++T + +P++ +S + AP V
Sbjct: 2615 SVEPVFSVVPPVTAVEIPISSEQTFYISGALQTFSATPVTAPSSFQAAPTSV 2666
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 85.9 bits (211), Expect = 1e-16
Identities = 167/814 (20%), Positives = 296/814 (36%), Gaps = 86/814 (10%)
Query: 38 KGSYSAKAYES--IRVSSELQQTWTKRKHG---------QEMTSKSLQTDTIVEEKKEVK 86
KGS A ES + EL + ++ G Q SKS TDT E+K
Sbjct: 68 KGSVPPAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSEQKLPG 127
Query: 87 LVEETV-VPEEKS-ADVREA--AIELPESVQDVEIPPNIPSVQLKMDRSQQTSRTGYWTM 142
T+ + E KS D++E + +P + +V + SV K + S +
Sbjct: 128 RSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEASQE 187
Query: 143 MNIPPVEKVDKEQQTYFSESEIVVISRPDSSSTKSK---EDALKHKSSGKIFASEHPEFQ 199
+ V KEQ + + +P K + D L+ + K +S+ PE
Sbjct: 188 ETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPE-- 245
Query: 200 PATNSNEEIGQKNISRTSFTQETKKGPPVLLEDELREEVTVPVVQEGSAVKKVASAEIEP 259
S K I + T +T L D R + + G +VK + +P
Sbjct: 246 -KIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKP 304
Query: 260 PSTEKFPAKIQPPLVEEATAKAEPRPAEETHVQVQPSTEETPDAEAATAVAENSVKVQPP 319
P + P K PP + K++P PA+ QPS P A+ V VQPP
Sbjct: 305 PIQQPTPGK--PPAQQPGHEKSQPGPAKPP---AQPSGLTKPLAQQPGTVKP---PVQPP 356
Query: 320 -----PAEEAPLVEFPAE---IQPPSAEESPSVELLAEILPPSAEESPSEEP-----PAE 366
PA+ + PA+ + PS+E+ P + LA+ PP ++P+++P P +
Sbjct: 357 GTTKPPAQPLGPAKPPAQQTGSEKPSSEQ-PGPKALAQ--PPGVGKTPAQQPGPAKPPTQ 413
Query: 367 ILPPPAEKSPSVELLGEIRSPSAQKAPIEVQPLPAEGALEEA------------------ 408
+ P + L ++P K P++ QP P + ++A
Sbjct: 414 QVGTPKPLAQQPGLQSPAKAPGPTKTPVQ-QPGPGKIPAQQAGPGKTSAQQTGPTKPPSQ 472
Query: 409 -PAKVEPPTVEETLADVQPLLPEEAPREEARELQLSTAMETPAEEAPTEFQSPLPKETTA 467
P +PP + A P P A + + P P+ Q K +
Sbjct: 473 LPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQ 532
Query: 468 EEASAEIQLLAATEPPADETPAEARSPLSEETSAEEAHAEVQSPLAEETTAEEASAEIQL 527
+ SA+ A PA + ++ P+S+ S + SP A++ ++ I
Sbjct: 533 QPGSAKPS--AQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICP 590
Query: 528 LAAIEAPADETPAEAQSPLSEETSAEEAPAEVQSPSAKGVSIEE---APLELQPPSGEET 584
L P +A E +P+ ++E +++ G +
Sbjct: 591 LCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDL 650
Query: 585 TAEEASAAIQLLAATEASAEEAPAEVQPPPAEEAPAEVQPPPAE--EAPAEVQPPPAEEA 642
+S +L A + A ++ P P + +P + P + +AP +PPP +
Sbjct: 651 APVPSSPQPKLKTAP-VTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQ 709
Query: 643 P-------AEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQSLPAEETPIEET 695
P A+ + PP ++ ++ PP P+E P + + + T + +
Sbjct: 710 PTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSS 769
Query: 696 LAAVHSPPADDVPAEEASVDKHSPPADLLLTEEFPIGEASAEVSPPPSEQTPEDEALVEN 755
+A P + + +K +PP L T+ + S P + +P D +
Sbjct: 770 SSATTKPDIPSSKVQSQAEEKTTPP---LKTDS---AKPSQSFPPTGEKVSPFDSKAIPR 823
Query: 756 VSTEFQSPQVAGIPAVKLGSVVLEGEAKFEEVSK 789
+++ + G + G ++ K EE K
Sbjct: 824 PASDSKIISHPGPSSESKGQKQVDPVQKKEEPKK 857
Score = 77.0 bits (188), Expect = 7e-14
Identities = 103/470 (21%), Positives = 176/470 (37%), Gaps = 82/470 (17%)
Query: 249 VKKVASAEIEP-PSTEKFPAKIQPPLVEEATAKAEPRPAEETHVQVQPSTEETPDAEAAT 307
+K+ ++ P PS+ + K P A +K+ P+P Q P + P + +
Sbjct: 642 MKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQ-----QTSPKKDAAPKQDLSK 696
Query: 308 AVAENSVKVQPPPAEEAPLVEFPAEIQPPSAE--ESPSVELLAEILPPSAEESPSEEPPA 365
A P P + PLV+ P PSA+ + P + L++ PP PSE+ A
Sbjct: 697 A---------PEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKA 747
Query: 366 EILPPPAEKSPSVELLGEIRSPSAQKAPIEVQPLPAEGALEEAPAKVEPPTVEETLADVQ 425
+ ++ V+ ++ S S+ ++ P+ +A K PP ++ Q
Sbjct: 748 PVADDKPKQPKMVKPTTDLVSSSSATTKPDI---PSSKVQSQAEEKTTPPLKTDSAKPSQ 804
Query: 426 PLLPEEAPREEARELQLSTAMETPAEEAPTEFQSPLPKETTAEEASAEIQLLAATEPPAD 485
P E+ S A+ PA ++ E+ ++ +Q
Sbjct: 805 SFPPTG---EKVSPFD-SKAIPRPASDSKIISHPGPSSESKGQKQVDPVQ--------KK 852
Query: 486 ETPAEARSPLSEETSAEEAHAEVQSPLAEETTAEEASAEIQLLAAIEAPADETPAEAQSP 545
E P +A++ +S + A+ +P TA + P QSP
Sbjct: 853 EEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQT----------------VPTPQQSP 896
Query: 546 LSEETSAEEAPAEVQSPSAKGVSIEEAPLELQPPSGEETTAEE-----ASAAIQLLAATE 600
+E S S SI +AP + QP + +ET + AS Q
Sbjct: 897 KPQEQSRRF--------SLNLGSITDAP-KSQPTTPQETVTGKLFGFGASIFSQASNLIS 947
Query: 601 ASAEEAPAEVQPP--PAEEAPAEVQPPPAEEAP---AEVQPPPAEEAP---------AEV 646
+ + P P P ++APA QPP ++ P + P PA+ P AE
Sbjct: 948 TAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEK 1007
Query: 647 QPPPAEEAP------AEVQPPPAEEAPAEVQPPPAEEAPAEVQSLPAEET 690
P AE+AP E +PPP +++ + P P +++ P E+
Sbjct: 1008 LEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPES 1057
Score = 70.5 bits (171), Expect = 6e-12
Identities = 124/573 (21%), Positives = 208/573 (36%), Gaps = 73/573 (12%)
Query: 241 PVVQEGSAVKKVASAEIEPPSTEKFPAKI--QPPLVEEATAKAEPRPAEETHVQV---QP 295
P G A E PS+E+ K QPP V + A+ +P PA+ QV +P
Sbjct: 362 PAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQ-QPGPAKPPTQQVGTPKP 420
Query: 296 STEETPDAEAATAVAENSVKVQPP-----PAEEA--------------PLVEFPAEIQPP 336
++ A A VQ P PA++A P + P +PP
Sbjct: 421 LAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPP 480
Query: 337 SAEESPSVELLAEILPPSAEESPSEEPPAEILPP--PAEKSPSVELLGEIRSPSAQKA-- 392
+ P+ + P + + PS++P + PP P PS + G + PS Q
Sbjct: 481 PQQPGPAKPPPQQ---PGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSA 537
Query: 393 -PIEVQPLPAEGALEEAPAKV---------EPPTVEETLADV--QPLLPEEAPREEAREL 440
P QP PA+ + +++ V +PPTV + Q L P EL
Sbjct: 538 KPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTEL 597
Query: 441 QLSTAMETPAEEAPTEFQS---------PLPKETTAEE-ASAEIQLLAATEPPADETPAE 490
L E TE Q+ P P T +E Q+ A P+
Sbjct: 598 LLHVP-EKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSS 656
Query: 491 ARSPLSEETSAEEAHAEVQSPLAEETTAEEASAEIQLLAAIEAPADETPAEAQSPLSEET 550
+ L + SP ++T+ ++ +A Q L+ P P Q L
Sbjct: 657 PQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSP 716
Query: 551 SAEEAPAEVQSPSAKGVSIEEAPLELQPPSGEETT--AEEASAAIQLLAATEASAEEAPA 608
SA+ Q P A +S P E PS ++ A++ +++ T + A
Sbjct: 717 SAKAK----QPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSA 772
Query: 609 EVQPP-PAEEAPAEVQ----PPPAEEA--PAEVQPPPAEEAP---AEVQPPPAEEAPAEV 658
+P P+ + ++ + PP ++ P++ PP E+ ++ P PA ++
Sbjct: 773 TTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIIS 832
Query: 659 QPPPAEEAPAE--VQPPPAEEAPAEVQSLPAEETPIEETLAAVHSPPADDVPAEEASVDK 716
P P+ E+ + V P +E P + Q+ + + + +PP A +
Sbjct: 833 HPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTP 892
Query: 717 HSPPADLLLTEEFPIGEASAEVSPPPSEQTPED 749
P + F + S +P TP++
Sbjct: 893 QQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQE 925
Score = 37.7 bits (86), Expect = 0.044
Identities = 87/489 (17%), Positives = 167/489 (34%), Gaps = 97/489 (19%)
Query: 47 ESIRVSSELQQTWTKRKHGQEMTS------KSLQTDTIVEEKKEVKLVEETVVPEEKSAD 100
E I+ S E ++ K+ Q++ S KS D I ++ VEE+ E
Sbjct: 1466 EEIKESQEERKDTFKKDSQQDIPSSKDHKEKSEFVDDITTRREPYDSVEESSESENSPVP 1525
Query: 101 VREAAIELPESVQDVEIPPNIPSVQLKMDRSQQTSRTGYWTMMNIPPVEKVDKEQQTYFS 160
R+ + S D + K + SQ + + I +E E +
Sbjct: 1526 QRKRRTSVGSSSSD----------EYKQEDSQGSGEEEDFIRKQI--IEMSADEDASGSE 1573
Query: 161 ESEIVVISRPDSSSTKSKEDALKHKSSGKIFASEHPEF--QPATNSNEEIGQKNISRTSF 218
+ E + + SS+ + + K GKI A +H + +T+ +E+ G+++
Sbjct: 1574 DDEFIRNQLKEISSSTESQKKEETKGKGKITAGKHRRLTRKSSTSIDEDAGRRHSWHDED 1633
Query: 219 TQETKKGPPVLLEDELREEVTVPVVQEGSAVKKVASAEIEPPSTEKFPAKIQPPLVEEAT 278
+ + P + + +E VV G +++ + E+ +K+ A E +
Sbjct: 1634 DEAFDESPELKYRETKSQESEELVVTGGGGLRRFKTIELNSTIADKYSA-------ESSQ 1686
Query: 279 AKAEPRPAEETHVQVQPSTEETPD---AEAATAVAENSVKVQPPPAEEAPLVEFPAEIQP 335
K EE ++++ T+ D E ++++ +S P + L E
Sbjct: 1687 KKTSLYFDEEPELEMESLTDSPEDRSRGEGSSSLHASSFTPGTSPTSVSSLDE------- 1739
Query: 336 PSAEESPSVELLAEILPPSAEESPSEEPPAEILPPPAEKSPSVELLGEIRSPSAQKAPIE 395
++ SPS + A P LL I S
Sbjct: 1740 ------------------DSDSSPSHKKGESKQQRKARHRPHGPLLPTIEDSSE------ 1775
Query: 396 VQPLPAEGALEEAPAKVEPPTVEETLADVQPLLPEEAPREEARELQLSTAMETPAEEAPT 455
EE L + + LL E+ + E + Q ++ + ++
Sbjct: 1776 ----------------------EEELREEEELLKEQEKQREIEQQQRKSSSKKSKKDK-- 1811
Query: 456 EFQSPLPKETTAEEASAEIQLLAATEPPADETPAEARSPLSEETSAEEAHAEVQSPLAEE 515
+E A+ + PP++ +P E SP E A E +S +E
Sbjct: 1812 ------------DELRAQRRRERPKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEY 1859
Query: 516 TTAEEASAE 524
+ + E+ E
Sbjct: 1860 SPSIESDPE 1868
Score = 36.2 bits (82), Expect = 0.13
Identities = 66/378 (17%), Positives = 128/378 (33%), Gaps = 49/378 (12%)
Query: 435 EEARELQLSTAMETPAEEAPTEFQSPLPKETTAE-EASAEIQLLAATEPPA---DETPAE 490
E++ E+ ST + P E L + + ASA+ +++ ++ + + +
Sbjct: 2221 EDSEEISSSTYFPGSIIDYPEEISVSLDRTAPPDGRASADHIVISLSDMASSIIESVVPK 2280
Query: 491 ARSPLSEETSAEEAHAEVQSPLAEETTAEEASAEIQLLAAIEAPADETPAEAQSPLSE-- 548
P+++ S + +E + P+ + A++ + +L +EA D+ EA+ S
Sbjct: 2281 PEGPVADTVSTDLLISE-KDPVKK---AKKETGNGIILEVLEAYRDKKELEAERTKSSLS 2336
Query: 549 ETSAEEAPAEVQSPSAKGVSIEEAPLELQPPSGEETTAEEASAAIQLLAATEAS------ 602
ET + P+ V + K + G+E A + + +++ A
Sbjct: 2337 ETVFDHPPSSVIALPMKE-QLSTTYFTSGETFGQEKPASQLPSGSPSVSSLPAKPRPFFR 2395
Query: 603 AEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPP 662
+ QPPP P PPP P + PPP P + A P
Sbjct: 2396 SSSLDISAQPPPPPPPPPPPPPPPPPPPPPPL-PPPTSPKPTILPKKKLTVASPVTTATP 2454
Query: 663 AEEAPAEVQ-------------------PPPAEEAPAEVQS------------LPAEETP 691
+A ++ PPP P+ + S P P
Sbjct: 2455 LFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKP 2514
Query: 692 IEETLAAVHSPPADDVPAEEASVDKHSPPADLLLTEEFPIGEASAEVSPPPSEQTPEDEA 751
+ L P D P S +L+ + ++ + ++ +SP ++ +P
Sbjct: 2515 VIPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLVTSADYKLPSPTSPLSPHSNKSSPRFSK 2574
Query: 752 LVENVSTEFQSPQVAGIP 769
+ P G P
Sbjct: 2575 SLTETYVVITLPSEPGTP 2592
Score = 34.7 bits (78), Expect = 0.37
Identities = 110/592 (18%), Positives = 189/592 (31%), Gaps = 150/592 (25%)
Query: 18 AIPKSSSPKATHRIGNTSGSKGSYSAKAYESIR-VSSELQQTWTKRKHGQEMTSKSLQTD 76
++P S +P T + + + S +SI V +E TK + +E++S +
Sbjct: 2175 SVPPSDTPSLTSSVSSVCTTDSSSPITTLDSITTVYTEPVDMITKFEDSEEISSSTYFPG 2234
Query: 77 TIVEEKKEVKLVEETVVPEEKSADVREAAIELPESVQDVEIPPNIPSVQLKMDRSQQTSR 136
+I++ +E+ + + P + A I L + + I SV K + +
Sbjct: 2235 SIIDYPEEISVSLDRTAPPDGRASADHIVISLSDMASSI-----IESVVPKPEGPVADTV 2289
Query: 137 TGYWTMMNIPPVEKVDKEQQTYFSESEIVVISRPDSSSTKSKEDALKHKSSGKIFASEHP 196
+ + PV+K KE +++ ++ K + +A + KSS +HP
Sbjct: 2290 STDLLISEKDPVKKAKKET------GNGIILEVLEAYRDKKELEAERTKSSLSETVFDHP 2343
Query: 197 EFQPATNSNEEIGQKNISRTSFTQETKKGPPVLLEDELREEVTVPVVQEGSAVKKVASAE 256
+E +S T FT G +E + GS
Sbjct: 2344 PSSVIALPMKE----QLSTTYFTSGETFG----------QEKPASQLPSGS--------- 2380
Query: 257 IEPPSTEKFPAKIQPPLVEEATAKAEPRPAEETHVQVQPSTEETPDAEAATAVAENSVKV 316
PS PAK PRP + + +
Sbjct: 2381 ---PSVSSLPAK--------------PRPFFRS--------------------SSLDISA 2403
Query: 317 QPPPAEEAPLVEFPAEIQPPSAEESPSVELLAEILPPSAEESPSEEPPAEILPPPAEKSP 376
QPPP PP PP P PP LPPP P
Sbjct: 2404 QPPPP-------------PP---------------PPPPPPPPPPPPPPPPLPPPTSPKP 2435
Query: 377 SV--ELLGEIRSPSAQKAP-------------IEVQPLPAEGALEEAPAKV--EPPTVEE 419
++ + + SP P + LP AP V +P ++
Sbjct: 2436 TILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPS 2495
Query: 420 TLADV---QPLLPEEAPREEARELQLSTAMETPAEEAPTEFQSPLPKETTAEEASAEIQL 476
L +P P AP+ +L +T T PT S T SA+ +L
Sbjct: 2496 GLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGL-SLTSSMTLNLVTSADYKL 2554
Query: 477 LAATEPPADET--------------------PAEARSPLSEETSAEEAHAEVQSPLAEET 516
+ T P + + P+E +P S + SP +
Sbjct: 2555 PSPTSPLSPHSNKSSPRFSKSLTETYVVITLPSEPGTPTDSSASQAITSWPLGSPSKDLV 2614
Query: 517 TAEEASAEIQLLAAIEAP--ADET-------PAEAQSPLSEETSAEEAPAEV 559
+ E + + + A+E P +++T + +P++ +S + AP V
Sbjct: 2615 SVEPVFSVVPPVTAVEIPISSEQTFYISGALQTFSATPVTAPSSFQAAPTSV 2666
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 84.0 bits (206), Expect = 5e-16
Identities = 131/570 (22%), Positives = 193/570 (33%), Gaps = 98/570 (17%)
Query: 256 EIEPPSTEKFPAKIQPPLVEEATAKAEPRPAEETHVQVQPSTE-----ETPDAEAATAVA 310
E PP+ P + P T + P + + + + E P A +A A
Sbjct: 101 ERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGA 160
Query: 311 ENSVKVQPPPAEEAPLV---------EFPAEIQPPSAEESPSVELLAEILPPSAEESPSE 361
P P +P + E PSA P E + + ++E S +E
Sbjct: 161 RRDTS-GPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTE 219
Query: 362 EPPAEILPPPAEKSPSVELLGEIRSPSAQKAPIEVQPL-------PAEGALEEAPAKVEP 414
PA A + PS G ++ P+++ PL P+ APA
Sbjct: 220 PSPA------ARRRPSAG--GGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQ 271
Query: 415 PTVEETLADVQPLLPEEA--PREEARELQ---LSTAMETPAEEAPTEFQSPLPKETTAEE 469
P + +Q L P + PR++A S+ + TP+ A + Q+P T
Sbjct: 272 PKPK----GLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHS 327
Query: 470 ASAEIQLLAATE--PPADETPAEARS-PLSEETSAEEAHAEVQSPLAEETTAEEASAEIQ 526
+S QL PP+ P ++ P T +A + SP + T + S +
Sbjct: 328 SSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLS 387
Query: 527 LLAAIEAPADETPAEAQSPLSEETSAEEAPA-------EVQSPSAKGVSIEEAPLE---- 575
LA P PA A PL S +P Q+P+A V + +AP
Sbjct: 388 PLAT--PPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPS 445
Query: 576 ------LQPPSGEETT--AEEASAAIQLLAATEASAEEAPAEVQPPPAEEAPAEVQPPPA 627
PP+ + A S A LAA +P P P PPP
Sbjct: 446 PPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPL 505
Query: 628 EEAPAEVQPPPAEEAPAEVQPP------PAEEAPAEVQPPPAEEAPAEVQPPPAEEAP-- 679
P ++ PP + PA PP P P + P+ P P +AP
Sbjct: 506 AAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPV 565
Query: 680 --AEVQSLPAEETPIEETLAAVHSPPADDVPAEEASVDKHSPPADLLLTEEFPIGEASAE 737
A + +P P TL A PP P + SV P L L A
Sbjct: 566 LAAPLLQVP-PSPPASPTLQAPRRPP---TPGPDTSVS--GPRLTLAL----------AP 609
Query: 738 VSPPPSEQTPEDEALVENVSTEFQSPQVAG 767
PPP ++P S+ P +AG
Sbjct: 610 GPPPPPSRSP---------SSTLSGPDLAG 630
Score = 42.4 bits (98), Expect = 0.002
Identities = 65/252 (25%), Positives = 89/252 (35%), Gaps = 35/252 (13%)
Query: 253 ASAEIEPPSTEKFPAKIQPPLVEEATAKAEPRPAEETHVQVQPSTEETPDAEA-----AT 307
AS + P +T P + PPL A+P P + P + P A A
Sbjct: 487 ASPPMSPSATP--PPQAPPPLAAPPLQLAKP-PPQAPPALATPPLQALPSPPASFPGQAP 543
Query: 308 AVAENSVKVQP---PPAEEAPLVEFPAEIQPPSAEESPSVELLAEILPPSAEESPSEEPP 364
S+ + P PP + P++ P PPS SP+++ A PP+ S P
Sbjct: 544 FSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQ--APRRPPTPGPDTSVSGP 601
Query: 365 AEIL------PPPAEKSPSVELLGEIRSPSAQKAPIEVQPLPAEGALEEAPAKVEPPTVE 418
L PPP +SPS L G + + A + L + E A PP
Sbjct: 602 RLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDA 661
Query: 419 ETLADVQPLLPEEAPREEARELQLSTAMETPAEEAPTEFQSPLPKETTAEEASAE-IQLL 477
E LA P P A AP +PLP SA+ + +
Sbjct: 662 E-LAACHPAAWSRGP-----------APPLAFRGAP---GAPLPWPPATGPGSADGLCTI 706
Query: 478 AATEPPADETPA 489
TE P TPA
Sbjct: 707 YETEGPESATPA 718
>gi|20143482 melanoma antigen family E, 1 [Homo sapiens]
Length = 957
Score = 83.6 bits (205), Expect = 7e-16
Identities = 126/534 (23%), Positives = 188/534 (35%), Gaps = 75/534 (14%)
Query: 306 ATAVAENSV--KVQPPPAEEAPLVEFPAEIQPPSAEESPSVELLAEILPPSAEESP-SEE 362
A A A NS ++Q P A P + P P +S ++ L PS P S E
Sbjct: 16 AKATAHNSSWGEMQAPNAPGLP-ADVPGSDVPQGPSDSQILQGLCASEGPSTSVLPTSAE 74
Query: 363 PPAEILPPPAEKSPSVELLGEIRSPSAQKAP-IEVQPLPAEGALEEAPAKVEPPTVEETL 421
P+ +PP ++ S P+ + P V P P+EG P PT+ + L
Sbjct: 75 GPSTFVPPTISEASSAS-----GQPTISEGPGTSVLPTPSEGLSTSGP-----PTISKGL 124
Query: 422 ADVQPLLPEEA---PREEARELQLSTAMETPAEEAPTEFQSPLPKETTAEEASAEIQLLA 478
L E R + ST++ A E P+ P P E T+
Sbjct: 125 CTSVTLAASEGRNTSRPPTSSEEPSTSVPPTASEVPSTSLPPTPGEGTS----------T 174
Query: 479 ATEPPADETPAEARSPLSEETSAEEAHAEVQSPLAEETTAEEASAEIQLLAAIEAPADET 538
+ P A E P+ + P +E + + +P T+ +A L +++A DE
Sbjct: 175 SVPPTAYEGPSTSVVPTPDEGPSTSV---LPTPGEGPGTSVPLAATEGLSTSVQATPDEG 231
Query: 539 PAEAQSPLSEE-TSAEEAPAEVQSPSAKGVSIEEAPLELQPPSGEETTAEEASAAIQLLA 597
P+ + P + E S P + PS + P G T+ A++ Q ++
Sbjct: 232 PSTSVPPTATEGLSTPVPPTRDEGPSTS--------VPATPGEGPSTSVLPAASDGQSIS 283
Query: 598 ATEASAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAE 657
+ + V P E VQP E + V P P V P EE
Sbjct: 284 LVPTRGKGSSTSVPPTATEGLSTSVQPTAGEGSSTSVPPTPGGGLSTSVPPTATEELSTS 343
Query: 658 VQPPPAEEAPAEVQPPPAEEAPAEVQSLPAE--ETPIEET----LAAVHSPPADDVPAEE 711
V P P E V P P E V ++ +T + T + + P A D P
Sbjct: 344 VPPTPGEGPSTSVLPIPGEGLSTSVPPTASDGSDTSVPPTPGEGASTLVQPTAPDGPGSS 403
Query: 712 ASVDKHSPPADLLLTEEFPIGEASAEVSPPPSEQTPEDEALVENVSTEFQSPQV--AGIP 769
+ P+ L +SA V PS+ S SP+V A +
Sbjct: 404 VLPNPGEGPSTLF--------SSSASVDRNPSK-----------CSLVLPSPRVTKASVD 444
Query: 770 AVKLGSVVLEGEAKFEEVSKINSVLKDLSNTNDGQAPTLEIESVFHIELKQRPP 823
+ G EG +FE VL+D + N L V I LK + P
Sbjct: 445 SDSEGPKGAEGPIEFE-------VLRDCESPNSISIMGLNTSRV-AITLKPQDP 490
Score = 70.9 bits (172), Expect = 5e-12
Identities = 101/412 (24%), Positives = 142/412 (34%), Gaps = 79/412 (19%)
Query: 254 SAEIEPPSTEKFPAKIQPPLVEEATAKAEPRPAEETHVQVQPSTEETPDAEAATAVAENS 313
S + P +E A QP + E P P+E P+ + A +E
Sbjct: 77 STFVPPTISEASSASGQPTISEGPGTSVLPTPSEGLSTSGPPTISKGLCTSVTLAASEGR 136
Query: 314 VKVQPPPAEEAPLVEFPAEIQPPSAEESPSVELLAEILPPSAEESPSEEPPAEILPPPAE 373
+PP + E P PP+A E PS LPP+ E S +PP A
Sbjct: 137 NTSRPPTSSEEPSTSV-----PPTASEVPSTS-----LPPTPGEGTSTS-----VPPTAY 181
Query: 374 KSPSVELLGEIRSPSAQKAP-IEVQPLPAEGALEEAPAKVEPPTVEETLADVQPLLPEEA 432
+ PS ++ P+ + P V P P EG P P E L+ P+E
Sbjct: 182 EGPSTSVV-----PTPDEGPSTSVLPTPGEG-----PGTSVPLAATEGLSTSVQATPDEG 231
Query: 433 PREEARELQLSTAMETPAEEAPTEFQSPLPKETTAEEASAEIQLLAATEPPADETPAEAR 492
P ST++ A E +P+P T +E +T PA TP E
Sbjct: 232 P---------STSVPPTATEG---LSTPVP--PTRDEG-------PSTSVPA--TPGEGP 268
Query: 493 SPLSEETSAEEAHAEVQSPLAEETTAEEASAEIQLLAAIEAPADETPAEAQSPLSEETSA 552
S TS A ++ QS T + +S + T E S + T+
Sbjct: 269 S-----TSVLPAASDGQSISLVPTRGKGSSTSV----------PPTATEGLSTSVQPTAG 313
Query: 553 EEAPAEVQSPSAKGVSIEEAPLELQPPSGEETTAEEASAAIQLLAATEASAEEAPAEVQP 612
E + V G+S P T EE S ++ E V P
Sbjct: 314 EGSSTSVPPTPGGGLSTSVPP----------TATEELSTSV-----PPTPGEGPSTSVLP 358
Query: 613 PPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAE 664
P E V P ++ + V P P E A VQP + + V P P E
Sbjct: 359 IPGEGLSTSVPPTASDGSDTSVPPTPGEGASTLVQPTAPDGPGSSVLPNPGE 410
Score = 67.4 bits (163), Expect = 5e-11
Identities = 61/235 (25%), Positives = 92/235 (39%), Gaps = 27/235 (11%)
Query: 492 RSPLSEETSAEEAHAEVQSPLAEETTAEEASAEI----------QLLAAIEAPADET-PA 540
R +++ T+ + E+Q+P A A+ +++ Q L A E P+ P
Sbjct: 12 RRRVAKATAHNSSWGEMQAPNAPGLPADVPGSDVPQGPSDSQILQGLCASEGPSTSVLPT 71
Query: 541 EAQSP-------LSEETSAEEAPAEVQSPSAKGVSIEEAPLELQPPSGEETTAEEASAAI 593
A+ P +SE +SA P + P G S+ P E SG T ++ ++
Sbjct: 72 SAEGPSTFVPPTISEASSASGQPTISEGP---GTSVLPTPSEGLSTSGPPTISKGLCTSV 128
Query: 594 QLLAATEASAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEE 653
L +A E +PP + E P+ PP A E P+ PP E + PP A E
Sbjct: 129 TL------AASEGRNTSRPPTSSEEPSTSVPPTASEVPSTSLPPTPGEGTSTSVPPTAYE 182
Query: 654 APAEVQPPPAEEAPAEVQPPPAEEAPAEVQSLPAEETPIEETLAAVHSPPADDVP 708
P+ P +E P+ P E P L A E A P+ VP
Sbjct: 183 GPSTSVVPTPDEGPSTSVLPTPGEGPGTSVPLAATEGLSTSVQATPDEGPSTSVP 237
Score = 38.9 bits (89), Expect = 0.020
Identities = 39/192 (20%), Positives = 65/192 (33%), Gaps = 34/192 (17%)
Query: 240 VPVVQEGSAVKKV------ASAEIEPPSTEKFPAKIQPPLVEEATAKAEPRP-------- 285
+P +G ++ V +S + P +TE +QP E ++ P P
Sbjct: 273 LPAASDGQSISLVPTRGKGSSTSVPPTATEGLSTSVQPTAGEGSSTSVPPTPGGGLSTSV 332
Query: 286 ----AEETHVQVQPSTEETPDAEAATAVAENSVKVQPPPAEEAPLVEFP-------AEIQ 334
EE V P+ E P E PP A + P + +
Sbjct: 333 PPTATEELSTSVPPTPGEGPSTSVLPIPGEGLSTSVPPTASDGSDTSVPPTPGEGASTLV 392
Query: 335 PPSAEESPSVELL-------AEILPPSAEESPSEEPPAEILPPPAEKSPSVELLGEIRSP 387
P+A + P +L + + SA + + +LP P SV+ + P
Sbjct: 393 QPTAPDGPGSSVLPNPGEGPSTLFSSSASVDRNPSKCSLVLPSPRVTKASVD--SDSEGP 450
Query: 388 SAQKAPIEVQPL 399
+ PIE + L
Sbjct: 451 KGAEGPIEFEVL 462
>gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo sapiens]
Length = 2524
Score = 82.0 bits (201), Expect = 2e-15
Identities = 163/738 (22%), Positives = 261/738 (35%), Gaps = 112/738 (15%)
Query: 40 SYSAKAYESIRVSSELQQTWTKRKHGQEMTSKSLQTDTIVEEKKEVKLVEETVVPEEKSA 99
+Y + S R + QQ +++ Q+ + + EEK E + +E EEK
Sbjct: 478 NYKSLVRRSYRRRGKSQQQQQQQQQQQQQQQQQPMPRSSQEEKDEKEKEKEAEKEEEKPE 537
Query: 100 DVREAAIELPESVQDVEIPPNIPSVQL----KMDRSQQTSRTGYWT--MMNIPPVEK-VD 152
+ L E D N + + + Q R G T M N E+ +
Sbjct: 538 VENDKEDLLKEKTDDTSGEDNDEKEAVASKGRKTANSQGRRKGRITRSMANEANSEEAIT 597
Query: 153 KEQQTYFSESEIVVISR-PDSSSTKSKEDALKHKSSGKIFASEHPEFQPATNSNEEIGQK 211
+Q + E+ SR + +K+ L+H + A +G K
Sbjct: 598 PQQSAELASMELNESSRWTEEEMETAKKGLLEHGRNWSAIA-------------RMVGSK 644
Query: 212 NISRT-SFTQETKKGPPVLLEDELREEVTVPVVQEGSAVKKVASAEIEPPSTEKFPAKIQ 270
+S+ +F KK + DE+ ++ + + +E +A +K A FP ++
Sbjct: 645 TVSQCKNFYFNYKKRQNL---DEILQQHKLKMEKERNARRKKKKAPAAASEEAAFPPVVE 701
Query: 271 PPLVEEATAKAEPRPAEETHVQVQPSTEETPDAEAA-TAVAENSVKVQPPPAEEAPLVEF 329
+E + E + S E P E + A NS + P+ +
Sbjct: 702 DEEMEASGVSGNEEEMVEEAEALHASGNEVPRGECSGPATVNNSSDTESIPSPHTEAAKD 761
Query: 330 PAEIQPPSAEESPSVELLAEILPPSAEESPSEEPPAEILPPPAEKSPSVELLGEIRSPSA 389
+ P P L A+ PP PP E +P P E +P+ E G +P+
Sbjct: 762 TGQNGP-----KPPATLGADGPPPGPPT-----PPPEDIPAPTEPTPASEATG---APTP 808
Query: 390 QKAPIEVQPLPAEGALEEAPAKVEPPTVEETLADVQPLLPEEAPREEARELQLSTAMETP 449
AP P+ PP P++P+E EE TA P
Sbjct: 809 PPAP---------------PSPSAPP----------PVVPKEEKEEE-------TAAAPP 836
Query: 450 AEEAPTEFQSPLPKETTAEEASAEIQLLAATEPPADETPAEARSPLSEETSAEEA-HAEV 508
EE E + P +E + AE + + A+E PA+ + + E +AE A AE
Sbjct: 837 VEEG-EEQKPPAAEELAVDTGKAEEPVKSECTEEAEEGPAKGKDAEAAEATAEGALKAEK 895
Query: 509 QSPLAEETTAEEASAEIQLLAAIEAPADETPAEAQSPLSEETSAEEAPAEVQSPSAKGVS 568
+ + T ++S AP D S S SA+E + K
Sbjct: 896 KEGGSGRATTAKSSG---------APQD-------SDSSATCSADE--VDEAEGGDKNRL 937
Query: 569 IEEAPLELQPPSGEETTAEEASAAIQLLAATEASAEEAP--AEVQPPPAEEAPAEVQPPP 626
+ P L P+G+ + L + +A P +V PP E+A PP
Sbjct: 938 LSPRP-SLLTPTGDPRANASPQKPLDLKQLKQRAAAIPPIVTKVHEPPREDAAPTKPAPP 996
Query: 627 AEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAE---EAP-------AEVQPPPAE 676
A P +QP E+ A QP + + PPA+ E P AE Q P
Sbjct: 997 APPPPQNLQP----ESDAPQQPGSSPRGKSRSPAPPADKEAEKPVFFPAFAAEAQKLPG- 1051
Query: 677 EAPAEVQSLPAEETPIEETLAAVHSPPADDVPAEEASVDKHSPPADLLLTEEFPIGEASA 736
+ P LP P E A+ H+P D A + H P L T +
Sbjct: 1052 DPPCWTSGLPFPVPPREVIKASPHAP---DPSAFSYAPPGHPLPLGLHDTARPVLPRPPT 1108
Query: 737 EVSPPPSEQTPEDEALVE 754
+PPP + + +++E
Sbjct: 1109 ISNPPPLISSAKHPSVLE 1126
Score = 37.0 bits (84), Expect = 0.075
Identities = 54/242 (22%), Positives = 82/242 (33%), Gaps = 30/242 (12%)
Query: 461 LPKETTAEEASAEIQLLAATEPPADETPAEARSPLSEETSAEEAHAEVQSPLAEETTAEE 520
L K TT + E + D +S L+ T+ E HA + P E+++
Sbjct: 1792 LTKPTTTSSSERERD----RDRERDRDREREKSILTSTTTVE--HAPIWRPGTEQSSGSS 1845
Query: 521 ASAEIQLLAAIEAPADETPAEAQSPLSEET--SAEEAPAEVQSPSAKGV----------- 567
S+ + PA + A SP+S T + ++ P+ + + KG+
Sbjct: 1846 GSSGGGG-GSSSRPASHSHAHQHSPISPRTQDALQQRPSVLHNTGMKGIITAVEPSTPTV 1904
Query: 568 ------SIEEAPLELQPPSGEETTAEEASAAIQLLAATEASAEEAPAEVQP--PPAEEAP 619
S P PP+ L +EAP +P P A+
Sbjct: 1905 LRSTSTSSPVRPAATFPPATHCPLGGTLDGVYPTLMEPVLLPKEAPRVARPERPRADTGH 1964
Query: 620 AEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQP-PPAEEA 678
A + PPA P P + PP + A + P AP P PPA A
Sbjct: 1965 AFLAKPPARSGLEPASSPSKGSEPRPLVPPVSGHATI-ARTPAKNLAPHHASPDPPAPPA 2023
Query: 679 PA 680
A
Sbjct: 2024 SA 2025
>gi|15559211 RE1-silencing transcription factor [Homo sapiens]
Length = 1097
Score = 81.3 bits (199), Expect = 3e-15
Identities = 141/631 (22%), Positives = 252/631 (39%), Gaps = 113/631 (17%)
Query: 76 DTIVEEKKEVKLVEETVVPEEKSADVREAAIELPESVQDVEIPP--NIPSVQLKMDRSQQ 133
D I EK E+ E+T + + + E +++ + E P N+ +Q+ +
Sbjct: 439 DNITNEKTEI---EQTKIKGDVAGKKNEKSVKAEKRDVSKEKKPSNNVSVIQVTTRTRKS 495
Query: 134 TSRTGYWTMMNIPPVEKVDKEQQTYFSESEIVVISRPDSSSTKSKEDALKHKSSGKIFAS 193
+ M++ +K +T S+ ++ V S +E + K K + +
Sbjct: 496 VTEV---KEMDVHTGSNSEKFSKTKKSKRKLEVDSHSLHGPVNDEESSTKKKKKVESKSK 552
Query: 194 EHPEFQPATNSNEEIGQKNISRTSFTQETKKGPPVLLEDELREEVTVPVVQEGSAVKKVA 253
+ + P +S E +K T + TKK L+++ ++ + P +E V+K
Sbjct: 553 NNSQEVPKGDSKVEENKKQ--NTCMKKSTKKKT---LKNKSSKKSSKPPQKE--PVEK-G 604
Query: 254 SAEIEPP--------STEKFPAKIQ-PPLVEEATAK-AEPRPAEETHVQVQ-----PSTE 298
SA+++PP + +K P +++ PP +E A + A+ RPA + VQ++ P+ +
Sbjct: 605 SAQMDPPQMGPAPTEAVQKGPVQVELPPPMEHAQMEGAQIRPAPDEPVQMEVVQEGPAQK 664
Query: 299 ET-PDAEAATAVAENSVKVQ---PPPAEEA--------PLVEFPAEIQPPSAEESPSVEL 346
E P E A V V PPP E A P PA+++ E +P +
Sbjct: 665 ELLPPVEPAQMVGAQIVLAHMELPPPMETAQTEVAQMGPAPMEPAQMEVAQVESAPMQVV 724
Query: 347 LAEILPPSAEESPSEE------------PPAEIL---PPPAEKSPSVELLGEIRSPSAQK 391
E P E SP E PP E++ P E SP +E++ QK
Sbjct: 725 QKE--PVQMELSPPMEVVQKEPVQIELSPPMEVVQKEPVKIELSPPIEVV--------QK 774
Query: 392 APIEVQPLPAEGALEEAPAKVEPPTVEETLADVQPLLPEEAPREEARELQLSTAMETPAE 451
P++++ P G +++ PA+ EPP E ++P+ + R++ +E
Sbjct: 775 EPVQMELSPPMGVVQKEPAQREPPPPREPPLHMEPISKKPPLRKDKKE------------ 822
Query: 452 EAPTEFQSPLPKETTAEEASAEIQLLAATEPPADETPAEARSPLSEETSAEEAHAEVQSP 511
+ QS + E+ E+ L+ + S L +E+ + E + P
Sbjct: 823 --KSNMQS---ERARKEQVLIEVGLVPVKD-----------SWLLKESVSTEDLSPPSPP 866
Query: 512 LAEETTAEEASAEIQLLAAIEAPADETPAEAQSPLSEETSAEEAPAEVQSPSA---KGVS 568
L +E EEAS + +LL E ++PL ++ AEEA + +A +
Sbjct: 867 LPKENLREEASGDQKLLNTGE-------GNKEAPL-QKVGAEEADESLPGLAANINESTH 918
Query: 569 IEEAPLELQPPSGEETTAEEASAAI--QLLAATEASAEEAPAEVQPPPAEEAPAEVQPPP 626
I + L P GE + + +I ++ T+ + E + E + P
Sbjct: 919 ISSSGQNLNTPEGETLNGKHQTDSIVCEMKMDTDQNTRENLTGINSTVEEPVSPMLPPSA 978
Query: 627 AEEAPA----EVQPPPAEEAPAEVQPPPAEE 653
EE A + PPA A E Q +E
Sbjct: 979 VEEREAVSKTALASPPATMAANESQEIDEDE 1009
Score = 67.4 bits (163), Expect = 5e-11
Identities = 125/551 (22%), Positives = 215/551 (39%), Gaps = 95/551 (17%)
Query: 97 KSADVREAAIELPESVQDVEIPPNIPSVQLKMDRSQQTSRTGYWTMMNIPPVEK--VDKE 154
K+ DV + ++ + ++ ++P NI + + ++++++ EK V KE
Sbjct: 418 KTMDVSKVKLKKTKK-READLPDNITNEKTEIEQTKIKGDVAGKKNEKSVKAEKRDVSKE 476
Query: 155 QQTYFSESEIVVISRPDSSSTKSKEDALK-----------HKSSGKIFASEHPEFQPATN 203
++ + S I V +R S T+ KE + KS K+ H P +
Sbjct: 477 KKPSNNVSVIQVTTRTRKSVTEVKEMDVHTGSNSEKFSKTKKSKRKLEVDSHSLHGPVND 536
Query: 204 SNEEIGQKNISRTSF---TQETKKGPPVLLEDELREEVTVPVVQEGSAVKKVASAEIEPP 260
+K + +QE KG + E++ + ++ + K + +PP
Sbjct: 537 EESSTKKKKKVESKSKNNSQEVPKGDSKVEENKKQNTCMKKSTKKKTLKNKSSKKSSKPP 596
Query: 261 STEKFPAKIQPPLVEEATAKAEPRPAEETHVQVQPSTEETPDAEAATAVAENSVKVQ-PP 319
E VE+ +A+ +P Q+ P+ E AV + V+V+ PP
Sbjct: 597 QKEP---------VEKGSAQMDPP-------QMGPAPTE--------AVQKGPVQVELPP 632
Query: 320 PAEEAPLVEF---PAEIQPPSAEESPSVELLAEILPPSAEESPSEEPPAEILPPPAEKSP 376
P E A + PA +P E E+LPP P++ A+I+ E P
Sbjct: 633 PMEHAQMEGAQIRPAPDEPVQMEVVQEGPAQKELLPPV---EPAQMVGAQIVLAHMELPP 689
Query: 377 SVELLGEIRSPSAQKAPIEVQPLPAEGA-LEEAPAKVEPPTVEETLADVQPLLPEEAPRE 435
+E ++ AQ P ++P E A +E AP +V V++ ++ P E ++
Sbjct: 690 PMETA---QTEVAQMGPAPMEPAQMEVAQVESAPMQV----VQKEPVQMELSPPMEVVQK 742
Query: 436 EARELQLSTAMETPAEEAPTEFQSP----LPKETTAEEASAEIQLL----AATEPPADET 487
E +++LS ME +E SP + KE E S + ++ A EPP
Sbjct: 743 EPVQIELSPPMEVVQKEPVKIELSPPIEVVQKEPVQMELSPPMGVVQKEPAQREPPPPRE 802
Query: 488 PAEARSPLSEETSAEEAHAEVQSPLAEETTAEEASAEIQLLAAIEAPADETPAEAQSPLS 547
P P+S++ + E + +E E+ E+ L+ P + L
Sbjct: 803 PPLHMEPISKKPPLRKDKKEKSNMQSERARKEQVLIEVGLV----------PVKDSWLLK 852
Query: 548 EETSAEEAPAEVQSPSAKGVSIEEAPLELQPPSGEETTAEEASAAIQLLAATEASAEEAP 607
E S E+ + PS PP +E EEAS +LL E + E
Sbjct: 853 ESVSTED----LSPPS--------------PPLPKENLREEASGDQKLLNTGEGNKE--- 891
Query: 608 AEVQPPPAEEA 618
A +Q AEEA
Sbjct: 892 APLQKVGAEEA 902
Score = 58.9 bits (141), Expect = 2e-08
Identities = 116/552 (21%), Positives = 198/552 (35%), Gaps = 104/552 (18%)
Query: 191 FASEHPEFQPATNSNEEIGQKNISRTSFTQETKKGPPVLLEDELREEVTVPVVQEGSAVK 250
F S+HP N ++ + + +T +E + E E+ + G +
Sbjct: 408 FKSKHPT---CPNKTMDVSKVKLKKTK-KREADLPDNITNEKTEIEQTKIKGDVAGKKNE 463
Query: 251 KVASAEIEPPSTEKFPAKIQPPLVEEATAKAEPRPAEETHVQVQPSTEETPDAEAATAVA 310
K AE S EK P+ + + +E V ++E+ + +
Sbjct: 464 KSVKAEKRDVSKEKKPSNNVSVIQVTTRTRKSVTEVKEMDVHTGSNSEKFSKTKKSKRKL 523
Query: 311 E-NSVKVQPPPAEEAPLVEFPAEIQPPS---AEESPSVELLAE-------ILPPSAEESP 359
E +S + P +E + +++ S ++E P + E + S ++
Sbjct: 524 EVDSHSLHGPVNDEESSTKKKKKVESKSKNNSQEVPKGDSKVEENKKQNTCMKKSTKKKT 583
Query: 360 SEEPPAEILPPPAEKSPSVELLGEIRSPSAQKAPIEVQPLPAEGALEEAPAKVEPPTVEE 419
+ ++ P +K P + SAQ P ++ P P E A+++ P +VE P
Sbjct: 584 LKNKSSKKSSKPPQKEP-------VEKGSAQMDPPQMGPAPTE-AVQKGPVQVELPP--- 632
Query: 420 TLADVQPLLPEEAPREEARELQLSTAMETPAEEAPTEFQSPLPKETTAEEASAEIQLLAA 479
P E A Q+ A PA + P + + +E A+ +LL
Sbjct: 633 -------------PMEHA---QMEGAQIRPAPDEPVQME-------VVQEGPAQKELLPP 669
Query: 480 TEPPADETPAEARSPLSEETSAEEAHAEVQSPLAEETTAEEASAEIQLLAAIEAPADETP 539
EP ++ A+ A ++ P ET E A PA P
Sbjct: 670 VEP-------------AQMVGAQIVLAHMELPPPMETAQTEV--------AQMGPAPMEP 708
Query: 540 AEAQSPLSEETSAEEAPAEVQSPSAKGVSIEEAPLELQPPSGEETTAEEASAAIQLLAAT 599
A+ E E AP +V V E +EL PP ++ I+L
Sbjct: 709 AQM-----EVAQVESAPMQV-------VQKEPVQMELSPPM---EVVQKEPVQIELSPPM 753
Query: 600 EASAEEAPAEVQPPPAEEAPAEVQPPPAEEAP--AEVQPPPAEEAPAEVQPPPAEEAPAE 657
E +E P +++ P E + +P E +P VQ PA+ +PPP E P
Sbjct: 754 EVVQKE-PVKIELSPPIEV-VQKEPVQMELSPPMGVVQKEPAQR-----EPPPPREPPLH 806
Query: 658 VQPPPAEEAPAEVQPPPAEEAPAEVQSLPAEETPIEETLAAVHSPPADD--VPAEEASVD 715
++P + PP + E ++ +E E+ L V P D + E S +
Sbjct: 807 MEPIS--------KKPPLRKDKKEKSNMQSERARKEQVLIEVGLVPVKDSWLLKESVSTE 858
Query: 716 KHSPPADLLLTE 727
SPP+ L E
Sbjct: 859 DLSPPSPPLPKE 870
>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
sapiens]
Length = 1362
Score = 81.3 bits (199), Expect = 3e-15
Identities = 134/664 (20%), Positives = 230/664 (34%), Gaps = 91/664 (13%)
Query: 154 EQQTYFSESEIVVISRPDSSSTKSKEDALKHKSSGKIFASEHPEFQPATNSNEEIGQK-- 211
++Q ++ +S+P + K KE K K K E E + + E +K
Sbjct: 515 QEQLKAVHEQLAALSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEPPPKKTK 574
Query: 212 -------NISRTSFTQETKKGPPVLLEDELREEVTVPVVQEGSAVKKVASAEIEPPSTEK 264
N+S+ K PP +E E+ P+ E K+ S +I EK
Sbjct: 575 KNNSSNSNVSKKEPAPMKSKPPPTYESEE--EDKCKPMSYEE---KRQLSLDINKLPGEK 629
Query: 265 FPAKIQPPLVEEATAK-AEPRPAEETHVQVQPSTEETPDAEAATAVAENSVKVQPPPAEE 323
+ E + K + P E ++PST + + + K + P AE+
Sbjct: 630 LGRVVHIIQSREPSLKNSNPDEIEIDFETLKPSTLRELERYVTSCLR----KKRKPQAEK 685
Query: 324 APLVEFPAEIQPPSAEESPSVELLAEILPPSAEESPSEEPPAEILPPPAEKSPSVELLGE 383
++ ++++ S+ ES S + S SE+ E+ P +K G
Sbjct: 686 VDVIAGSSKMKGFSSSESESSS--------ESSSSDSEDSETEMAPKSKKKGHP----GR 733
Query: 384 IRSPSAQKAPIEVQPLPAEGALEEAPAKVEPPTVEETLADVQPLLPEEAPREEARELQLS 443
+ ++Q PA + P +PP QP P P
Sbjct: 734 EQKKHHHHHHQQMQQAPAPVPQQPPPPPQQPPPPPPPQQQQQPPPPPPPP---------- 783
Query: 444 TAMETPAEEAPTEFQSPLPKETTAEEASAEIQLLAA--------TEP----PADETPAEA 491
P + AP SP P T + E QL + T+P P E P
Sbjct: 784 ---SMPQQAAPAMKSSPPPFIAT-QVPVLEPQLPGSVFDPIGHFTQPILHLPQPELPPHL 839
Query: 492 RSPLSEETSAE-EAHAEVQSPLAEETTAEEASAEIQLLAAIEA----PADETPAEAQSPL 546
P T HA V P ++ S AA+ P +PA Q+PL
Sbjct: 840 PQPPEHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPARPPAVSPALTQTPL 899
Query: 547 SEETSAEEAPA---EVQSPSAKGVSIEEAPLELQPPSGEETTAEEASAAIQLLAATEASA 603
+ + P E + P A ++ + L LQ ++ LL + + +
Sbjct: 900 LPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQ-------LQKVQPPTPLLPSVKVQS 952
Query: 604 EEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAE------EAPAE 657
+ P + PPP ++Q P P + QPPP ++ QPPP +
Sbjct: 953 QPPPP-LPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQH----QPPPRPVHLQPMQFSTH 1007
Query: 658 VQPPPAEEAPAEVQPPPAEEAPAEVQSLPAEETPIEETLAAVHSPPADDVPAEEASVDKH 717
+Q PP + PPP ++ P P + ++ + HSP +
Sbjct: 1008 IQQPPPPQGQQPPHPPPGQQPP------PPQPAKPQQVIQHHHSPRHHKSDPYSTGHLRE 1061
Query: 718 SPPADLLLTEEFPIGEASAEVSPPPSEQTPEDEALVENVSTEFQSPQVAGIPAVKLGSVV 777
+P ++ + + ++ SPP P+ + L ++ Q + + K+ S +
Sbjct: 1062 APSPLMIHSPQMSQFQSLTHQSPPQQNVQPKKQEL--RAASVVQPQPLVVVKEEKIHSPI 1119
Query: 778 LEGE 781
+ E
Sbjct: 1120 IRSE 1123
Score = 52.8 bits (125), Expect = 1e-06
Identities = 98/528 (18%), Positives = 183/528 (34%), Gaps = 83/528 (15%)
Query: 280 KAEPRPAEETHVQVQPST------EETPDAEAATAVAENSVKVQPPPAEEAPLVEFPAEI 333
K P EET + + + +ET A+ + N+ + PP + P +
Sbjct: 160 KINELPTEETEIMIVQAKGRGRGRKETGTAKPGVSTVPNTTQASTPPQTQTP------QP 213
Query: 334 QPPSAEESPSVELLAEILPPSAEESPSEEPPAEILPPPAEKSPSVELLGEIRSPSAQKAP 393
PP + +P P + + P ++PP ++P P
Sbjct: 214 NPPPVQATPHP------FPAVTPDLIVQTPVMTVVPPQPLQTPP---------------P 252
Query: 394 IEVQPLPAEGALEEAPAKVEPPTVEETLADVQPLLPEEAPREEARELQLSTAMETPAEEA 453
+ QP P + P + PP + T QP+ ++ + +A +T P E
Sbjct: 253 VPPQPQPPPAPAPQ-PVQSHPPIIAAT---PQPVKTKKGVKRKADTTTPTTI--DPIHEP 306
Query: 454 PTEFQSPLPKETTAEEASAEIQLLAATEPPADETPAEARSPLSEETSAEEAHAEVQSPLA 513
P+ LP E + + +PP + P + P E++S + S +
Sbjct: 307 PS-----LPPEPKTTKLGQRRESSRPVKPPKKDVPDSQQHPAPEKSSKVSEQLKCCSGIL 361
Query: 514 EETTAEEASA---------EIQLLA------AIEAPADETPAEAQSPLSEETSAEEAPAE 558
+E A++ +A +++ L I+ P D + +++ E A+E A+
Sbjct: 362 KEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGAD 421
Query: 559 VQSPSAKGVSIEEAPLELQPPSGEETT-AEEASAAIQLLAATEASAEEAPAEVQPPPAEE 617
V+ + + PP E A + ++ A E P PA
Sbjct: 422 VRLMFSN-------CYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPEEPVVAVSSPAVP 474
Query: 618 APAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEE-APAEVQPPPAEEAPAEVQPPPAE 676
P +V PP+ + ++ + + + A+ A + Q E A + P
Sbjct: 475 PPTKVVAPPSSSDSSSDSSSDSDSSTDDSEEERAQRLAELQEQLKAVHEQLAALSQPQ-- 532
Query: 677 EAPAEVQSLPAEETPIEETLAAVHSPPADDVPAEEASVDKHSPPADLLLTEEFPIGEASA 736
Q+ P ++ ++ ++V + S K PP +
Sbjct: 533 ------QNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEPPPKKTKKNNSSNSNVSKK 586
Query: 737 EVSP----PPSEQTPEDEALVENVSTEFQ---SPQVAGIPAVKLGSVV 777
E +P PP E+E + +S E + S + +P KLG VV
Sbjct: 587 EPAPMKSKPPPTYESEEEDKCKPMSYEEKRQLSLDINKLPGEKLGRVV 634
Score = 51.2 bits (121), Expect = 4e-06
Identities = 112/548 (20%), Positives = 176/548 (32%), Gaps = 88/548 (16%)
Query: 178 KEDALKHKSSGKIFASEHPEFQPATNSNEEIGQKNISRTSFTQETKK-GPPVLLEDELRE 236
K D + S K F+S E ++S++ S T ++KK G P + +
Sbjct: 685 KVDVIAGSSKMKGFSSSESESSSESSSSDS----EDSETEMAPKSKKKGHPGREQKKHHH 740
Query: 237 EVTVPVVQEGSAVKKVASAEIEPPSTEKFPAKIQPPLVEEATAKAEPRPAEETHVQVQPS 296
+ Q + V + +PP + P PP ++ P P+ Q P+
Sbjct: 741 HHHQQMQQAPAPVPQ------QPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQ--QAAPA 792
Query: 297 TEETPDAEAATAVAENSVKVQ----------PPPAEEAPLVEFPAEI-QPPSAEESPSVE 345
+ +P AT V ++ P P E P + QPP P +
Sbjct: 793 MKSSPPPFIATQVPVLEPQLPGSVFDPIGHFTQPILHLPQPELPPHLPQPPEHSTPPHLN 852
Query: 346 LLAEILPPSAEESPSEEPP-----AEILPPPAEKSPSVELLGEIRSPSAQKAPIEVQPLP 400
A + PP+ + ++P A LPP + P+V SP+ + P+ QP
Sbjct: 853 QHAVVSPPALHNALPQQPSRPSNRAAALPPKPARPPAV-------SPALTQTPLLPQPPM 905
Query: 401 AEGAL-----EEAPA----------------KVEPPTVEETLADVQ-----PLLPEEAPR 434
A+ EE PA KV+PPT VQ PL P P
Sbjct: 906 AQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPS 965
Query: 435 EEARELQLSTAMETPAEEAPTEFQS---PLPKETTAEEASAEIQLLAATEPPADETPAEA 491
+ + Q P + P + Q P P + S IQ +PP +
Sbjct: 966 VQQQLQQQPPPPPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQ-----QPPPPQGQQPP 1020
Query: 492 RSPLSEETSAEEAHAEVQSPLAEETTAEEASAEIQLLAAIEAPADETPAEAQSPLSEETS 551
P ++ + Q + S EAP+ P SP
Sbjct: 1021 HPPPGQQPPPPQPAKPQQVIQHHHSPRHHKSDPYSTGHLREAPS---PLMIHSP------ 1071
Query: 552 AEEAPAEVQSPSAKGVSIEEAPLELQPPSGEETTAEEASAAIQLLAATEASAEEAPAEVQ 611
Q + ++ + P + P +E A L+ E +
Sbjct: 1072 --------QMSQFQSLTHQSPPQQNVQPKKQELRAASVVQPQPLVVVKEEKIHSPIIRSE 1123
Query: 612 PPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQ 671
P P + P + +AP + P E P +V P PP A + + Q
Sbjct: 1124 PFSPSLRPEPPKHPESIKAPVHLPQRP-EMKPVDVGRPVIRPPEQNAPPPGAPDKDKQKQ 1182
Query: 672 PPPAEEAP 679
P AP
Sbjct: 1183 EPKTPVAP 1190
Score = 35.8 bits (81), Expect = 0.17
Identities = 48/200 (24%), Positives = 73/200 (36%), Gaps = 25/200 (12%)
Query: 520 EASAEIQLLAAIEAPADETP-----AEAQSPLSEET-SAEEAPAEVQSPSAKGVSIEEAP 573
EA ++ L E P +ET A+ + +ET +A+ + V + + +
Sbjct: 151 EALEKLFLQKINELPTEETEIMIVQAKGRGRGRKETGTAKPGVSTVPNTTQASTPPQTQT 210
Query: 574 LELQPPSGEETTAEEASAAIQLLAATEASAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAE 633
+ PP + T + L+ T P +Q PP P + QPPPA
Sbjct: 211 PQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPP--VPPQPQPPPA------ 262
Query: 634 VQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQSLPAEETPIE 693
PA P + PP P V+ + A+ P + E SLP E +
Sbjct: 263 ----PA-PQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPIHEPPSLPPEPKTTK 317
Query: 694 -----ETLAAVHSPPADDVP 708
E+ V PP DVP
Sbjct: 318 LGQRRESSRPV-KPPKKDVP 336
>gi|116325993 c114 SLIT-like testicular protein [Homo sapiens]
Length = 1700
Score = 81.3 bits (199), Expect = 3e-15
Identities = 158/699 (22%), Positives = 267/699 (38%), Gaps = 127/699 (18%)
Query: 149 EKVDKEQQTYFSESEIVVISRPDSSSTKSKEDALKHKSSGKIF--ASEHPEFQPATNSNE 206
+K+ K+ +S +EI+ I+R S+ K+ SS S PE + S+E
Sbjct: 148 KKLKKDPAQRWSLAEIIGITRQLSTPQSQKQTLQNEYSSTDTPYPGSLPPELR--VKSDE 205
Query: 207 EIG-QKNISRTSFTQETKKGPPVLLEDELREEVTVPVVQEGSAVKKVASAEIEPPSTEKF 265
G + + + F E + P LED + S++++ A A++ P E+
Sbjct: 206 PPGPSEQVGPSQFHLEPETQNPETLEDI-----------QSSSLQQEAPAQL-PQLLEEE 253
Query: 266 PAKIQ---PPLVEEATAKAEPRPAEETHVQVQ---------PSTEETPDAEAATAVAENS 313
P+ +Q P L E++ ++ P E VQ P+ P T +E +
Sbjct: 254 PSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPT 313
Query: 314 VKVQPPPAEEAPLVEFPAEIQPPSAEE----SPSVELLAEILPPSAEESPSE--EPPAEI 367
+ + A++ ++FP E++P + ++ P V + L S ++ P + E P E+
Sbjct: 314 NETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQQQPVQPSESPREV 373
Query: 368 LPPPAEKS---------------PSVELLGEIRSPSAQKAPIEVQ-PLPAEGALE----- 406
P ++ P + SPS P +VQ + AE + E
Sbjct: 374 ESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSL 433
Query: 407 ---EAPAK-------VEPPTVEETLADVQPLLPEEAPREEARELQLSTAMETP-----AE 451
EA + VEPP ++ PLLPE + +Q T+ ++P
Sbjct: 434 VHQEATTRLSGSGNDVEPPAIQH---GGPPLLPESSEEAGPLAVQQETSFQSPEPINNEN 490
Query: 452 EAPTEFQSPLPKETTAEEASA------------EIQLLAATEPPADETPAEAR-SPLS-E 497
+PT+ ++ TAEE + E + +PP +A PL
Sbjct: 491 PSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLG 550
Query: 498 ETSAEEAHAEVQ-SPLAEETTAEEASAEIQLLAAIEAPADETPA--EAQSPLSEETSAE- 553
T E+ EV+ SP +ET + + L + + TP +AQ P+S + +
Sbjct: 551 FTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQL 610
Query: 554 ---------EAPAEV---QSPSAKGVSIEEAPLELQPPSGEETTAEEAS-AAIQLLAATE 600
E EV P VS + + L P +T + A +Q L
Sbjct: 611 LDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGF 670
Query: 601 ASAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAE-VQPPPAEEAPAEVQ 659
++ EV+P A A PPP EV PP+++ A+ A P +++
Sbjct: 671 TITPKSMTEVEPSTALMTTA---PPPGH---PEVTLPPSDKGQAQHSHLTQATVQPLDLE 724
Query: 660 PPPAEEAPAEVQP-PPAEEAPAEVQSLPAEETPIEETLAAVHSPPADDVPAEEASVDKHS 718
+ EV+P P EE + L P E T HS + A
Sbjct: 725 LTITTKPTTEVKPSPTTEETSTQPPDLGLAIIP-EPTTETRHSTALEKTTA--------- 774
Query: 719 PPADLLLTEEFPIGEASAEVSPPPSEQTPEDEALVENVS 757
P D + T + + EV+ PP+E P ++LV++ S
Sbjct: 775 PRPDRVQT----LHRSLTEVTGPPTELEPAQDSLVQSES 809
Score = 67.8 bits (164), Expect = 4e-11
Identities = 114/480 (23%), Positives = 183/480 (38%), Gaps = 84/480 (17%)
Query: 318 PPPAEEAPLVEFPAEIQPPSAEESPSVELLAEILPPSAEESPSEEPPAEILPPPAEKSPS 377
PP + + FP E P A P+ + L PSA S E PA PP E + +
Sbjct: 56 PPDSWSSHSSHFPRE--SPHAPTLPADPWDFDHLGPSA----SSEMPA----PPQESTEN 105
Query: 378 VELLGEIRSPSAQKAPIEVQPLPAEGALEEAPAKVEPPTVEETLADVQPLLPEEAPREEA 437
+ + SA + P+E + A + ++ K+ P +E L P+ P++ ++ A
Sbjct: 106 LVPFLDTWD-SAGEQPLEPEQFLA--SQQDLKDKLSP---QERL----PVSPKKLKKDPA 155
Query: 438 RELQLSTAMETPAEEAPTEFQSPLPKETTAEEASAEIQLLAATEPPADETPAEARSPLSE 497
+ L+ + + + + Q K+T E S+ + PP ++ SE
Sbjct: 156 QRWSLAEIIGITRQLSTPQSQ----KQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSE 211
Query: 498 ETSAEEAHAE--VQSPLAEETTAEEASAEIQLLAAIEAPADETPAEAQSPLSEETSA--E 553
+ + H E Q+P ET + S+ +Q E PA+ L EE S+ +
Sbjct: 212 QVGPSQFHLEPETQNP---ETLEDIQSSSLQ---------QEAPAQLPQLLEEEPSSMQQ 259
Query: 554 EAPAEVQSPSAKGVSIEEAPLELQPPSGEET-------TAEEASAAIQLLAA----TEAS 602
EAPA S + +++ + +QPP ++ T + A + + + TE+S
Sbjct: 260 EAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPTNETESS 319
Query: 603 AEEA------PAEVQPPPA-EEAPAEVQPPPAE---EAPAEVQPPPAEEAPAEVQPPPAE 652
+ P EV+P +EAP E PP E + QP E+P EV+ P +
Sbjct: 320 QAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQQQPVQPSESPREVESSPTQ 379
Query: 653 EAPAEVQP--------PPAEEAPAEVQPPPAEEAPAEVQSLPAEETPIEETLAAVHSPPA 704
+ P PP + P P +VQ A E E + VH
Sbjct: 380 QETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEAT 439
Query: 705 DDVPAEEASVDKHSPPADLLLTEEFPIGEASAEVSPPPSEQTPEDEALVENVSTEFQSPQ 764
+ V+ PPA I + P SE E L T FQSP+
Sbjct: 440 TRLSGSGNDVE---PPA---------IQHGGPPLLPESSE---EAGPLAVQQETSFQSPE 484
>gi|110665701 leucine rich repeat containing 37A [Homo sapiens]
Length = 1700
Score = 81.3 bits (199), Expect = 3e-15
Identities = 158/699 (22%), Positives = 267/699 (38%), Gaps = 127/699 (18%)
Query: 149 EKVDKEQQTYFSESEIVVISRPDSSSTKSKEDALKHKSSGKIF--ASEHPEFQPATNSNE 206
+K+ K+ +S +EI+ I+R S+ K+ SS S PE + S+E
Sbjct: 148 KKLKKDPAQRWSLAEIIGITRQLSTPQSQKQTLQNEYSSTDTPYPGSLPPELR--VKSDE 205
Query: 207 EIG-QKNISRTSFTQETKKGPPVLLEDELREEVTVPVVQEGSAVKKVASAEIEPPSTEKF 265
G + + + F E + P LED + S++++ A A++ P E+
Sbjct: 206 PPGPSEQVGPSQFHLEPETQNPETLEDI-----------QSSSLQQEAPAQL-PQLLEEE 253
Query: 266 PAKIQ---PPLVEEATAKAEPRPAEETHVQVQ---------PSTEETPDAEAATAVAENS 313
P+ +Q P L E++ ++ P E VQ P+ P T +E +
Sbjct: 254 PSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPT 313
Query: 314 VKVQPPPAEEAPLVEFPAEIQPPSAEE----SPSVELLAEILPPSAEESPSE--EPPAEI 367
+ + A++ ++FP E++P + ++ P V + L S ++ P + E P E+
Sbjct: 314 NETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQQQPVQPSESPREV 373
Query: 368 LPPPAEKS---------------PSVELLGEIRSPSAQKAPIEVQ-PLPAEGALE----- 406
P ++ P + SPS P +VQ + AE + E
Sbjct: 374 ESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSL 433
Query: 407 ---EAPAK-------VEPPTVEETLADVQPLLPEEAPREEARELQLSTAMETP-----AE 451
EA + VEPP ++ PLLPE + +Q T+ ++P
Sbjct: 434 VHQEATTRLSGSGNDVEPPAIQH---GGPPLLPESSEEAGPLAVQQETSFQSPEPINNEN 490
Query: 452 EAPTEFQSPLPKETTAEEASA------------EIQLLAATEPPADETPAEAR-SPLS-E 497
+PT+ ++ TAEE + E + +PP +A PL
Sbjct: 491 PSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLG 550
Query: 498 ETSAEEAHAEVQ-SPLAEETTAEEASAEIQLLAAIEAPADETPA--EAQSPLSEETSAE- 553
T E+ EV+ SP +ET + + L + + TP +AQ P+S + +
Sbjct: 551 FTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQL 610
Query: 554 ---------EAPAEV---QSPSAKGVSIEEAPLELQPPSGEETTAEEAS-AAIQLLAATE 600
E EV P VS + + L P +T + A +Q L
Sbjct: 611 LDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGF 670
Query: 601 ASAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAE-VQPPPAEEAPAEVQ 659
++ EV+P A A PPP EV PP+++ A+ A P +++
Sbjct: 671 TITPKSMTEVEPSTALMTTA---PPPGH---PEVTLPPSDKGQAQHSHLTQATVQPLDLE 724
Query: 660 PPPAEEAPAEVQP-PPAEEAPAEVQSLPAEETPIEETLAAVHSPPADDVPAEEASVDKHS 718
+ EV+P P EE + L P E T HS + A
Sbjct: 725 LTITTKPTTEVKPSPTTEETSTQPPDLGLAIIP-EPTTETGHSTALEKTTA--------- 774
Query: 719 PPADLLLTEEFPIGEASAEVSPPPSEQTPEDEALVENVS 757
P D + T + + EV+ PP+E P ++LV++ S
Sbjct: 775 PRPDRVQT----LHRSLTEVTGPPTELEPAQDSLVQSES 809
Score = 67.8 bits (164), Expect = 4e-11
Identities = 114/480 (23%), Positives = 183/480 (38%), Gaps = 84/480 (17%)
Query: 318 PPPAEEAPLVEFPAEIQPPSAEESPSVELLAEILPPSAEESPSEEPPAEILPPPAEKSPS 377
PP + + FP E P A P+ + L PSA S E PA PP E + +
Sbjct: 56 PPESWSSHSSHFPRE--SPHAPTLPADPWDFDHLGPSA----SSEMPA----PPQESTEN 105
Query: 378 VELLGEIRSPSAQKAPIEVQPLPAEGALEEAPAKVEPPTVEETLADVQPLLPEEAPREEA 437
+ + SA + P+E + A + ++ K+ P +E L P+ P++ ++ A
Sbjct: 106 LVPFLDTWD-SAGEQPLEPEQFLA--SQQDLKDKLSP---QERL----PVSPKKLKKDPA 155
Query: 438 RELQLSTAMETPAEEAPTEFQSPLPKETTAEEASAEIQLLAATEPPADETPAEARSPLSE 497
+ L+ + + + + Q K+T E S+ + PP ++ SE
Sbjct: 156 QRWSLAEIIGITRQLSTPQSQ----KQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSE 211
Query: 498 ETSAEEAHAE--VQSPLAEETTAEEASAEIQLLAAIEAPADETPAEAQSPLSEETSA--E 553
+ + H E Q+P ET + S+ +Q E PA+ L EE S+ +
Sbjct: 212 QVGPSQFHLEPETQNP---ETLEDIQSSSLQ---------QEAPAQLPQLLEEEPSSMQQ 259
Query: 554 EAPAEVQSPSAKGVSIEEAPLELQPPSGEET-------TAEEASAAIQLLAA----TEAS 602
EAPA S + +++ + +QPP ++ T + A + + + TE+S
Sbjct: 260 EAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPTNETESS 319
Query: 603 AEEA------PAEVQPPPA-EEAPAEVQPPPAE---EAPAEVQPPPAEEAPAEVQPPPAE 652
+ P EV+P +EAP E PP E + QP E+P EV+ P +
Sbjct: 320 QAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQQQPVQPSESPREVESSPTQ 379
Query: 653 EAPAEVQP--------PPAEEAPAEVQPPPAEEAPAEVQSLPAEETPIEETLAAVHSPPA 704
+ P PP + P P +VQ A E E + VH
Sbjct: 380 QETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEAT 439
Query: 705 DDVPAEEASVDKHSPPADLLLTEEFPIGEASAEVSPPPSEQTPEDEALVENVSTEFQSPQ 764
+ V+ PPA I + P SE E L T FQSP+
Sbjct: 440 TRLSGSGNDVE---PPA---------IQHGGPPLLPESSE---EAGPLAVQQETSFQSPE 484
>gi|47132519 Ras association and pleckstrin homology domains 1 isoform
1 [Homo sapiens]
Length = 1250
Score = 80.5 bits (197), Expect = 6e-15
Identities = 112/528 (21%), Positives = 178/528 (33%), Gaps = 77/528 (14%)
Query: 276 EATAKAEPRPAEETHVQVQPSTEETPDAEAATAVAENSVKVQPPPAEEAPLVEFPAEIQP 335
E ++KA + + P P ++ S + PPP P P
Sbjct: 588 EESSKARMESMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPP---------P 638
Query: 336 PSAEESPSVELLAEILPPSAEESPSEEPPAEILPPPAEKSPSVELLGEIRSPSAQKAPIE 395
P P L ++ P + +P + I S L P Q ++
Sbjct: 639 PPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVK 698
Query: 396 VQPL-PAEGALEEAPAKVEPPTVEETLADVQPL-----LPEEA---PREEARELQLSTAM 446
Q L P G + P PPT +A ++P LP+ + P + ++Q T +
Sbjct: 699 PQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQV 758
Query: 447 ETPAEEAPTEFQSPLPKET-----------TAEEASAEIQLLAATEPPADETPAEARSPL 495
P P +PLP + T+ + A + AA P P + P
Sbjct: 759 APPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPA 818
Query: 496 SEETSAEEAHAEVQSPLAEETTAEEASAEIQLLAAIEAPADETPAEAQSPLSEETSAEEA 555
+ + P+ T ++ S A P SPLS S +
Sbjct: 819 FPASYIPPSPPTPPVPVPPPTLPKQQS-----FCAKPPP---------SPLSPVPSVVKQ 864
Query: 556 PAEVQSPSAKGVSIEEAPLELQPPSGEETTAEEASAAIQLLAATEASAEEAPAEVQPPPA 615
A P ++E PL+ P + A ++ A++ + S+ P+ PPP
Sbjct: 865 IASQFPPPPTPPAMESQPLKPVPAN----VAPQSPPAVKAKPKWQPSSIPVPSPDFPPPP 920
Query: 616 EEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPA 675
E+ PPP PA PPP +P P +P + +P +PPP
Sbjct: 921 PESSLVFPPPPPSPVPAPPPPPPPTASPT----PDKSGSPG--KKTSKTSSPGGKKPPPT 974
Query: 676 EEAPAEVQSLPAEETPIEETLAAVHSPPADDVPAEEASVDKHSPPADLLLTEEFPIGEAS 735
P + I+ + A H P P+ ++ V K +PPA+ G S
Sbjct: 975 ----------PQRNSSIKSSSGAEHPEPKR--PSVDSLVSKFTPPAE--------SGSPS 1014
Query: 736 AEVSPPPSEQTPEDEALVENVSTEFQSPQVAGIPAVKLGSVVLEGEAK 783
E PPP+ + + V+ P V V + VL G K
Sbjct: 1015 KETLPPPAAPPKPGKLNLSGVNL----PGVLQQGCVSAKAPVLSGRGK 1058
Score = 54.7 bits (130), Expect = 3e-07
Identities = 89/397 (22%), Positives = 133/397 (33%), Gaps = 48/397 (12%)
Query: 459 SPLPKETTAEEASAEIQLLAATEPPADETPAEARSPLSEETSAEEAHAEVQSPL-AEETT 517
SP PK T AS L PP P P S A +P+ + +T
Sbjct: 610 SPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYST 669
Query: 518 AEEASAEIQLLAAIEAPADETPAEAQS-------PLSEETSAEEAPAEVQSPSAKGVSIE 570
Q A+ P ++QS P + P +P + ++
Sbjct: 670 ITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLK 729
Query: 571 EAPLELQPPSGEETTAEEASAAIQLLAATEASAEEAPAEVQPPPAEEAPAEVQPPP---- 626
AP PS + +A I + + + AP PPP AP Q PP
Sbjct: 730 PAPCA---PSLPQFSAPPPPLKIHQV---QHITQVAPPTPPPPPPIPAPLPPQAPPKPLV 783
Query: 627 ---AEEAPAEVQPPPAEEAPAEVQPP--PAEEAPAEVQP--PPAEEAPAEVQPPP----- 674
A + V P + AP PP PA++ PA PP+ P PPP
Sbjct: 784 TIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQ 843
Query: 675 ----AEEAPAEVQSLP------AEETPIEETLAAVHSPPADDVPAEEA--------SVDK 716
A+ P+ + +P A + P T A+ S P VPA A + K
Sbjct: 844 QSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPK 903
Query: 717 HSPPADLLLTEEFPIGEASAEVSPPPSEQTPEDEALVENVSTEFQSPQVAGIPAVKLGSV 776
P + + + +FP + + PP +P T +P +G P K
Sbjct: 904 WQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKT 963
Query: 777 VLEGEAKFEEVSKINSVLKDLSNTNDGQAPTLEIESV 813
G K + NS +K S + ++S+
Sbjct: 964 SSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSL 1000
Score = 47.8 bits (112), Expect = 4e-05
Identities = 80/383 (20%), Positives = 141/383 (36%), Gaps = 38/383 (9%)
Query: 241 PVVQEGSAVKKVASAEIEPPSTEKFPAKIQPPLVE-EATAKAEPRPAEETHVQVQPSTEE 299
P+ S VK++AS + PP T PA PL A + PA + + QPS+
Sbjct: 854 PLSPVPSVVKQIAS-QFPPPPTP--PAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIP 910
Query: 300 TPDAEAATAVAENSVKVQPPPAEEAPLVEFPAEIQPPSAEESPSVELLAEILPPSAEESP 359
P + E+S+ PPP P P PP+A +P + P + S
Sbjct: 911 VPSPDFPPPPPESSLVFPPPPPSPVPA---PPPPPPPTASPTPD-----KSGSPGKKTSK 962
Query: 360 SEEPPAEILPPPAEKSPSVELLGEIRSPSAQKAPIEVQPLPAEGALEEAPAKVEPPTVEE 419
+ P + PP +++ S I+S S + P P +++ +K PP E
Sbjct: 963 TSSPGGKKPPPTPQRNSS------IKSSSGAE-----HPEPKRPSVDSLVSKFTPP-AES 1010
Query: 420 TLADVQPLLPEEAPREEAR----ELQLSTAMETPAEEAPTEFQSPLPKETTAEEASAEIQ 475
+ L P AP + + + L ++ A S K++ E S
Sbjct: 1011 GSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSD 1070
Query: 476 LLAATEPPADE---TPAEARSPLSEETSAEEAHAEVQSPLAEETTAEEASAEIQLLAAIE 532
PP E P E + S TS + A Q + + ++A +
Sbjct: 1071 SDFPPPPPETELPLPPIEIPAVFSGNTSPKVAVVNPQPQQWSKMSVKKAPPPTR------ 1124
Query: 533 APADETPAEAQSPLSEETSAEEAPAEVQSPSAKGVSIEEAPL-ELQPPSGEETTAEEASA 591
+++ Q+ +SE+ + +V + +S++ L +L ++ S
Sbjct: 1125 PKRNDSTRLTQAEISEQPTMATVVPQVPTSPKSSLSVQPGFLADLNRTLQRKSITRHGSL 1184
Query: 592 AIQLLAATEASAEEAPAEVQPPP 614
+ ++ A + + A PPP
Sbjct: 1185 SSRMSRAEPTATMDDMALPPPPP 1207
>gi|91982772 mucin 17 [Homo sapiens]
Length = 4493
Score = 80.5 bits (197), Expect = 6e-15
Identities = 175/866 (20%), Positives = 280/866 (32%), Gaps = 160/866 (18%)
Query: 18 AIPKSSSPKATHRIGNTSGSKGSYSAKAYESIRVSSE-------LQQTWTKRKHGQEMTS 70
+IP S++P A+ S + ++ S VSS QT T +TS
Sbjct: 2106 SIPLSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSPIPTEGTSMQTSTYSDRRTPLTS 2165
Query: 71 KSLQTDTIVEEKKEVKLVE--ETVVPEEKSADVREAAIELPESVQDVEIPPNIPSVQLKM 128
+ T + +T P S + R + P + + +P + PS
Sbjct: 2166 MPVSTTVVASSAISTLSTTPVDTSTPVTNSTEARSS----PTTSEGTSMPTSTPS----- 2216
Query: 129 DRSQQTSRTGYWTMMNIPPVEKVDKEQQTYFSESEIVVISRPDSSSTKSKEDALKHKSSG 188
+ +T M + + V E T + V S P ++ST++ + +
Sbjct: 2217 ------EGSTPFTSMPVSTMPVVTSEASTLSATP--VDTSTPVTTSTEATSSPTTAEGTS 2268
Query: 189 KIFASEHPEFQPATN--------SNEEIGQKNI----SRTSFTQETKKGPP------VLL 230
++ P T+ +N E+ + S T FT T+ P +
Sbjct: 2269 IPTSTLSEGTTPLTSIPVSHTLVANSEVSTLSTTPVDSNTPFTTSTEASSPPPTAEGTSM 2328
Query: 231 EDELREEVTVPVVQEGSAVKKVASAEIEPPSTEKFPAKIQPPLVEEATAKAEPRPAEETH 290
E P+ + + VAS E ST PA P+ + A + P A++T
Sbjct: 2329 PTSTSSEGNTPLTRMPVSTTMVASFETSTLSTT--PADTSTPVTTYSQAGSSPTTADDTS 2386
Query: 291 -----------------------VQVQPSTEETPDAEAATAVAEN-------------SV 314
V + ST T + +T V + S+
Sbjct: 2387 MPTSTYSEGSTPLTSVPVSTMPVVSSEASTHSTTPVDTSTPVTTSTEASSSPTTAEGTSI 2446
Query: 315 KVQPPPAEEAPLVEFPAEIQPPSAEESPSVEL----LAEILPPSAEESPSEEPPAEILPP 370
PP PL P P + E+ ++ + + S E S S +I+ P
Sbjct: 2447 PTSPPSEGTTPLASMPVSTTPVVSSEAGTLSTTPVDTSTPMTTSTEASSSPTTAEDIVVP 2506
Query: 371 PAEKSPSVELLGEI----------------------RSPSAQKAPIEVQPLPAEGALEEA 408
+ S LL I SP I AEG
Sbjct: 2507 ISTASEGSTLLTSIPVSTTPVASPEASTLSTTPVDSNSPVVTSTEISSSATSAEGTSMPT 2566
Query: 409 PAKVEPPTVEETL-ADVQPLLPEEAPREEARELQLSTAMETPAEEA---PTEFQSPLPKE 464
E T ++ +PL EA + S + T E + T + +P
Sbjct: 2567 STYSEGSTPLRSMPVSTKPLASSEASTLSTTPVDTSIPVTTSTETSSSPTTAKDTSMPIS 2626
Query: 465 TTAEEASAEIQLLAATEPPADE-------TPAEARSPL-------SEETSAEEAHAEVQS 510
T +E +++ +L +T P A TP + R+ + S T+AE + +
Sbjct: 2627 TPSEVSTSLTSILVSTMPVASSEASTLSTTPVDTRTLVTTSTGTSSSPTTAEGSSMPTST 2686
Query: 511 PLAEETTAEEASAEIQLLAAIEAPA-DETPAEAQSPLSEETSAEEAPAEVQSPSAK---- 565
P T LLA EA TP + +P++ A +P + S +
Sbjct: 2687 PGERSTPLTNILVSTTLLANSEASTLSTTPVDTSTPVTTSAEASSSPTTAEGTSMRISTP 2746
Query: 566 --------GVSIEEAPLELQPPSGEETTAEEASAAIQLLAATEASAEEAPAEVQPPPAEE 617
+ + P+ S TTA + S I + +TEAS+ AEV P
Sbjct: 2747 SDGSTPLTSILVSTLPVASSEASTVSTTAVDTS--IPVTTSTEASSSPTTAEVTSMPT-S 2803
Query: 618 APAEVQPP----PAEEAP-AEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQP 672
P+E P P P A + P + P A P AE +
Sbjct: 2804 TPSETSTPLTSMPVNHTPVASSEAGTLSTTPVDTSTPVTTSTKASSSPTTAEGIVVPIS- 2862
Query: 673 PPAEEAPAEVQSLPAEETPIEETLAAVHS--PPADDVPAEEASVDKHSPPADLLLTEEFP 730
A E + S+P TP+ + A+ S P +P ++ SP T E
Sbjct: 2863 -TASEGSTLLTSIPVSTTPVASSEASTLSTTPVDTSIPVTTSTEGSSSP-----TTAE-- 2914
Query: 731 IGEASAEVSPPPSEQTPEDEALVENV 756
S +S P TP LV V
Sbjct: 2915 --GTSMPISTPSEVSTPLTSILVSTV 2938
Score = 75.9 bits (185), Expect = 1e-13
Identities = 112/515 (21%), Positives = 175/515 (33%), Gaps = 77/515 (14%)
Query: 241 PVVQEGSAVKKVASAEIEPPSTEKFPAKIQPPLVEEATAKAEPRPAEETHVQVQPSTEET 300
P EGS++ E P T ++ T A + + V ST T
Sbjct: 2674 PTTAEGSSMPTSTPGERSTPLTN---------ILVSTTLLANSEASTLSTTPVDTSTPVT 2724
Query: 301 PDAEAA---TAVAENSVKVQPPPAEEAPLVEFPAEIQPPSAEESPSVELLA---EILPPS 354
AEA+ T S+++ P PL P ++ E+ +V A I +
Sbjct: 2725 TSAEASSSPTTAEGTSMRISTPSDGSTPLTSILVSTLPVASSEASTVSTTAVDTSIPVTT 2784
Query: 355 AEESPSEEPPAEILPPPAEKSPSVELLGEIRSPSAQKAPIEVQPLPAE--GALEEAPAKV 412
+ E+ S AE+ P +PS E +P P+ P+ + G L P
Sbjct: 2785 STEASSSPTTAEVTSMPTS-TPS-----ETSTPLTSM-PVNHTPVASSEAGTLSTTPVDT 2837
Query: 413 EPPTVEETLADVQPLLPEEAPREEARELQLSTAMET-PAEEAPTEFQSPLPKETTAEEAS 471
P T A P E + + ST + + P P TT + S
Sbjct: 2838 STPVTTSTKASSSPTTAEGIVVPISTASEGSTLLTSIPVSTTPVASSEASTLSTTPVDTS 2897
Query: 472 AEIQLLAATEPPADETPAEARS-PLSEETSAEEAHAEVQSPLAE--ETTAEEASAEIQLL 528
I + +TE + T AE S P+S + EV +PL +T A +E L
Sbjct: 2898 --IPVTTSTEGSSSPTTAEGTSMPISTPS-------EVSTPLTSILVSTVPVAGSEASTL 2948
Query: 529 AAIEAPADETPAEAQSPLSEETSAEEAPAEVQSPSAKGVSIEEAPLELQPPSGEETTAEE 588
+ TP + ++P++ A +P +A+G S + + P T
Sbjct: 2949 ST-------TPVDTRTPVTTSAEASSSPT-----TAEGTS-----MPISTPGERRTPLTS 2991
Query: 589 ASAAIQLLAATEASA-EEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPP-----PAEEA 642
S + +A++EAS PA+ P A P AE + P P
Sbjct: 2992 MSVSTMPVASSEASTLSRTPADTSTPVTTSTEASSSPTTAEGTGIPISTPSEGSTPLTSI 3051
Query: 643 PAEVQPPPAEEA------PAEVQPPPAEEAPAEVQPPPAEEAPAEVQS----------LP 686
P P EA P + P P PAE + + +P
Sbjct: 3052 PVSTTPVAIPEASTLSTTPVDSNSPVVTSTEVSSSPTPAEGTSMPISTYSEGSTPLTGVP 3111
Query: 687 AEETPI-EETLAAVHSPPADDVPAEEASVDKHSPP 720
TP+ ++ + + P D S + HS P
Sbjct: 3112 VSTTPVTSSAISTLSTTPVDTSTPVTTSTEAHSSP 3146
Score = 72.4 bits (176), Expect = 2e-12
Identities = 116/552 (21%), Positives = 177/552 (32%), Gaps = 72/552 (13%)
Query: 252 VASAEIEPPSTEKFPAKIQPPLVEEATAKAEPRPAEETHVQVQPSTEET------PDAEA 305
VA++E ST P P+V + P PAE T + +E + P +
Sbjct: 1820 VANSEASTLSTT--PVDSNSPVVTSTAVSSSPTPAEGTSIATSTPSEGSTALTSIPVSTT 1877
Query: 306 ATAVAENSVKVQPPPAEEAPLVEFPAEIQPPSAEESPSVELLAEILPPSAEESPSE-EPP 364
A +E + P P+ + P+ + S +P S +P E PP
Sbjct: 1878 TVASSETNTLSTTPAVTSTPVTTYAQVSSSPTTADGSS-------MPTS---TPREGRPP 1927
Query: 365 AEILPPPAEKSPSVEL------LGEIRSPSAQKAPIEVQPLPAEGALEEAPAKVEPPTVE 418
+P S E+ L + R+P + P A+G PA E T
Sbjct: 1928 LTSIPVSTTTVASSEINTLSTTLADTRTPVTTYSQASSSPTTADGTSMPTPAYSEGSTPL 1987
Query: 419 ETLA-DVQPLLPEEAPREEARELQLSTAMET-------PAEEAPTEFQSPLPKETTAEEA 470
++ ++ EA + ST T P T Q+ P E T A
Sbjct: 1988 TSMPLSTTLVVSSEASTLSTTPVDTSTPATTSTEGSSSPTTAGGTSIQTSTPSERTTPLA 2047
Query: 471 SAEIQLLA---------ATEPPADETPAEARSPLSEETSAEEAHAEVQSPLAEETTAEEA 521
+ +T P +T + S +AE + + +P
Sbjct: 2048 GMPVSTTLVVSSEGNTLSTTPVDSKTQVTNSTEASSSATAEGSSMTISAPSEGSPLLTSI 2107
Query: 522 SAEIQLLAAIEAPA-DETPAEAQSPL--SEETSAEEAPAEVQSPSAKGVSIEEAPLELQP 578
+A+ EA TP ++ SP+ S E S+ P E S S PL P
Sbjct: 2108 PLSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSPIPTEGTSMQTSTYSDRRTPLTSMP 2167
Query: 579 PSGEETTAEEASAAIQLLAATEASAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPP- 637
S T AS+AI L+ T P + P A P +E P
Sbjct: 2168 VS----TTVVASSAISTLSTT-------PVDTSTPVTNSTEARSSPTTSEGTSMPTSTPS 2216
Query: 638 ----PAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQSLPAEETPIE 693
P P P EA P + P A AE T I
Sbjct: 2217 EGSTPFTSMPVSTMPVVTSEAST------LSATPVDTSTPVTTSTEATSSPTTAEGTSIP 2270
Query: 694 ETLAAVHSPPADDVPAEEASV--DKHSPPADLLLTEEFPIGEASAEVSPPPSEQTPEDEA 751
+ + + P +P V + S + + P ++ SPPP T E +
Sbjct: 2271 TSTLSEGTTPLTSIPVSHTLVANSEVSTLSTTPVDSNTPFTTSTEASSPPP---TAEGTS 2327
Query: 752 LVENVSTEFQSP 763
+ + S+E +P
Sbjct: 2328 MPTSTSSEGNTP 2339
Score = 70.9 bits (172), Expect = 5e-12
Identities = 165/817 (20%), Positives = 270/817 (33%), Gaps = 84/817 (10%)
Query: 18 AIPKSSSPKATHRIGNTSGSKGSYSAKAYESIRVSSE-------LQQTWTKRKHGQEMTS 70
++P S++P A+ N S + + S SS T T + +TS
Sbjct: 456 SMPVSTTPVASSEASNLSTTPVDSKTQVTTSTEASSSPPTAEVNSMPTSTPSEGSTPLTS 515
Query: 71 KSLQTDTIVEEKKEVKLVEETVVPEEKSADVREAAIELPESVQDVEIPPNIPSVQLKMDR 130
S+ T + E + T V A + + IP + PS
Sbjct: 516 MSVSTMPVASS--EASTLSTTPVDTSTPVTTSSEASSSSTTPEGTSIPTSTPS------- 566
Query: 131 SQQTSRTGYWTMMNIPPVEKVDKEQQTYFSESEIVVISRPDSSSTKSKEDALKHKSSGKI 190
T T + + T + V S SSS+ + E S+
Sbjct: 567 EGSTPLTNMPVSTRLVVSSEASTTSTTPADSNTFVTTSSEASSSSTTAEGTSMPTST--- 623
Query: 191 FASEHPEFQPATNSNEEIGQKNISRTSFTQETKKGPPVLLEDELREEVTVPVVQEGSAVK 250
SE + + + + + + T T PV E T EG+++
Sbjct: 624 -YSERGTTITSMSVSTTLVASSEASTLSTTPVDSNTPVTTSTEATSSSTTA---EGTSMP 679
Query: 251 KVASAEIEPPSTEKFPAKIQPPLVEEATAKAEPRPAEETHVQVQ-PSTEETPDAEAATAV 309
E P T P+ A +E T V P T T + + T
Sbjct: 680 TSTYTEGSTPLTSM-------PVNTTLVASSEASTLSTTPVDTSTPVTTSTEASSSPTTA 732
Query: 310 AENSVKVQPPPAEEAPLVEFPAEIQPPSAEESPSVELLAEILPPSAEESPSEEPPAEILP 369
S+ P PL P ++ E+ ++ L S + S E A P
Sbjct: 733 DGASMPTSTPSEGSTPLTSMPVSKTLLTSSEASTLSTTP--LDTSTHITTSTE--ASCSP 788
Query: 370 PPAEKSPSVELLGEIRSPSAQKAPIEVQPL--PAEGALEEAPAKVEPPTVEETLADVQPL 427
E + SP P+ + P+ P L P P T P
Sbjct: 789 TTTEGTSMPISTPSEGSPLLTSIPVSITPVTSPEASTLSTTPVDSNSPVTTSTEVSSSPT 848
Query: 428 LPEEAPREEARELQLSTAMETPAEEAPTEFQSPLPKETTAEEASAEIQLLAATE-----P 482
E T+M T + +P TT SA I L+ T P
Sbjct: 849 PAE------------GTSMPTSTYSEGRTPLTSMPVSTTLVATSA-ISTLSTTPVDTSTP 895
Query: 483 PADETPAEARSPLSEETSAEEAH-AEVQSPLAE--ETTAEEASAEIQLLAAIEAPADETP 539
+ T A + SE TS + E +PL ++T S+E + L+A TP
Sbjct: 896 VTNSTEARSSPTTSEGTSMPTSTPGEGSTPLTSMPDSTTPVVSSEARTLSA-------TP 948
Query: 540 AEAQSPLSEETSAEEAPAEVQSPSAKGVSIEEAPLELQPPSGEETTAEEASAAIQLLAAT 599
+ +P++ T A +P +A+G SI + PS T + L+A +
Sbjct: 949 VDTSTPVTTSTEATSSPT-----TAEGTSIPTST-----PSEGTTPLTSTPVSHTLVANS 998
Query: 600 EASAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQ 659
EAS P + PPP E + P+E + + P + A +
Sbjct: 999 EASTLSTTPVDSNTPLTTSTEASSPPPTAEGTSMPTSTPSEGSTPLTRMPVSTTMVASSE 1058
Query: 660 PPPAEEAPAEVQPPPAEEAPAEVQSLPAEETPIEETLAAVHSPPADDVPAEEASV--DKH 717
PA+ P + A S A+ T + + + S P VP V +
Sbjct: 1059 TSTLSTTPADTSTPVTTYSQASSSSTTADGTSMPTSTYSEGSTPLTSVPVSTRLVVSSEA 1118
Query: 718 SPPADLLLTEEFPIGEASAEVSPPPSEQTPEDEALVENVSTEFQSPQVAGIPAVKLGSVV 777
S + + P+ S E S P+ T E ++ + +E +P +A +P ++V
Sbjct: 1119 STLSTTPVDTSIPV-TTSTEASSSPT--TAEGTSIPTSPPSEGTTP-LASMPVST--TLV 1172
Query: 778 LEGEAKFEEVSKINSVLKDLSNTN-DGQAPTLEIESV 813
+ EA + ++S + ++T PT E+ S+
Sbjct: 1173 VSSEANTLSTTPVDSKTQVATSTEASSPPPTAEVTSM 1209
Score = 69.3 bits (168), Expect = 1e-11
Identities = 128/586 (21%), Positives = 206/586 (35%), Gaps = 82/586 (13%)
Query: 237 EVTVPVVQEGSAVKKVASAEIEPPSTEKFPAKIQPPLVEEATAKAEPRPAEETHVQVQPS 296
EV+ P+ + VA +E ST P + P+ A A + P AE T + +
Sbjct: 2925 EVSTPLTSILVSTVPVAGSEASTLSTT--PVDTRTPVTTSAEASSSPTTAEGTSMPIS-- 2980
Query: 297 TEETPDAEAATAVAENSVKVQPPPAEEAP-LVEFPAEIQPP--SAEESPSVELLAE---- 349
TP E T + SV P + EA L PA+ P ++ E+ S AE
Sbjct: 2981 ---TP-GERRTPLTSMSVSTMPVASSEASTLSRTPADTSTPVTTSTEASSSPTTAEGTGI 3036
Query: 350 -ILPPSAEESPSEEPPAEILPPPAEKSPSVELLG-EIRSPSAQKAPIEVQPLPAEGALEE 407
I PS +P P P ++ ++ + SP + P PAEG
Sbjct: 3037 PISTPSEGSTPLTSIPVSTTPVAIPEASTLSTTPVDSNSPVVTSTEVSSSPTPAEGTSMP 3096
Query: 408 APAKVEPPTVEETLADVQPLLPEEAPREEARELQLSTAMETPAEEAPTEFQSPLPKETTA 467
E T PL +ST TP + + +P+ TT+
Sbjct: 3097 ISTYSEGST---------PLTGVPVSTTPVTSSAISTLSTTPVDTS-----TPV---TTS 3139
Query: 468 EEASAEIQLLAATEPPADETPAEARSPLSEETSAEEAHAEVQSPLAEETTAEEASAEIQL 527
EA + T P TP+E +PL+ + V + L S+E
Sbjct: 3140 TEAHSSPTTSEGTSMPTS-TPSEGSTPLT--------YMPVSTMLV-------VSSEDST 3183
Query: 528 LAAIEAPAD-ETPAEAQSPLSEETSAEEAPAEVQSPSAKGVSIEEAPLELQPPSGEETT- 585
L+A P D TP + + T+AE +PS + P+ P + E +
Sbjct: 3184 LSA--TPVDTSTPVTTSTEATSSTTAEGTSIPTSTPSEGMTPLTSVPVSNTPVASSEASI 3241
Query: 586 --AEEASAAIQLLAATEASAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAP 643
+ L +TEAS+ PP E + P+E + P +
Sbjct: 3242 LSTTPVDSNTPLTTSTEASSS--------PPTAEGTSMPTSTPSEGSTPLTSMPVSTTTV 3293
Query: 644 AEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQSLPAEETPIEETLAAVHSPP 703
A + PA+ P + A PP A+ + TP+ T + + P
Sbjct: 3294 ASSETSTLSTTPADTSTPVTTYSQASSSPPIADGTSMPTSTYSEGSTPL--TNMSFSTTP 3351
Query: 704 ADDVPAEEASVDKHSPPADLLLTEEFPIGEAS-AEVSPPPSEQTPEDEALVENVSTEFQS 762
V + EAS +P + P+ ++ A +SP +E T + +T S
Sbjct: 3352 ---VVSSEASTLSTTP-----VDTSTPVTTSTEASLSPTTAEGTSIPTSSPSEGTTPLAS 3403
Query: 763 PQVAGIPAVKLGSVVLEGEAKFEEVSKINSVLKDLSNTNDGQAPTL 808
V+ P V+ E + ++S ++T +PT+
Sbjct: 3404 MPVSTTP-------VVSSEVNTLSTTPVDSNTLVTTSTEASSSPTI 3442
Score = 66.6 bits (161), Expect = 9e-11
Identities = 101/534 (18%), Positives = 167/534 (31%), Gaps = 73/534 (13%)
Query: 241 PVVQEGSAVKKVASAEIEPPSTEKFPAKIQPPLVEEATAKAEPRPAEETHVQVQ-PSTEE 299
P +G+++ A +E P T PL +E T V P+T
Sbjct: 1967 PTTADGTSMPTPAYSEGSTPLTSM-------PLSTTLVVSSEASTLSTTPVDTSTPATTS 2019
Query: 300 TPDAEAATAVAENSVKVQPPPAEEAPLVEFPAEIQPPSAEESPS-----VELLAEILPPS 354
T + + T S++ P PL P + E + V+ ++ +
Sbjct: 2020 TEGSSSPTTAGGTSIQTSTPSERTTPLAGMPVSTTLVVSSEGNTLSTTPVDSKTQVTNST 2079
Query: 355 -AEESPSEEPPAEILPPPAEKSPSVELLGEIRSPSAQKAPIEVQPLPAEGALEEAPAKVE 413
A S + E + + P+E SP + + +P A P L P
Sbjct: 2080 EASSSATAEGSSMTISAPSEGSPLLTSIPLSTTPVAS---------PEASTLSTTPVDSN 2130
Query: 414 PPTVEETLADVQPLLPEEAPREEARELQLSTAMETPAEEAPTEFQSPLPKETTAEEASAE 473
P + T P+ E T+M+T + +P TT +SA
Sbjct: 2131 SPVITSTEVSSSPIPTE------------GTSMQTSTYSDRRTPLTSMPVSTTVVASSAI 2178
Query: 474 IQLLAATEPPADETPAEARSPLSEETSAEEAHAEVQSPLAEETTAEEASAEIQLLAAIEA 533
L TP + +P++ T A + + +T E S +
Sbjct: 2179 STL--------STTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPSEGSTPFTSMPVSTM 2230
Query: 534 PA--------DETPAEAQSPLSEETSAEEAPAEVQSPSAKGVSIEEA--PLELQPPSGEE 583
P TP + +P++ T A +P + S ++ E PL P S
Sbjct: 2231 PVVTSEASTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGTTPLTSIPVSHTL 2290
Query: 584 TTAEEASAAIQLLAATEASAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAP 643
E S + + PPP E + +E + P +
Sbjct: 2291 VANSEVSTLSTTPVDSNTPFTTSTEASSPPPTAEGTSMPTSTSSEGNTPLTRMPVSTTMV 2350
Query: 644 AEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAE----------EAPAEVQSLPAEETPIE 693
A + PA+ P + A P A+ E + S+P P+
Sbjct: 2351 ASFETSTLSTTPADTSTPVTTYSQAGSSPTTADDTSMPTSTYSEGSTPLTSVPVSTMPVV 2410
Query: 694 ETLAAVHS-PPADDVPAEEASVDKHSPPADLLLTEEFPIGEASAEVSPPPSEQT 746
+ A+ HS P D S + S P E ++ + PPSE T
Sbjct: 2411 SSEASTHSTTPVDTSTPVTTSTEASSSPT---------TAEGTSIPTSPPSEGT 2455
Score = 63.2 bits (152), Expect = 1e-09
Identities = 114/537 (21%), Positives = 168/537 (31%), Gaps = 63/537 (11%)
Query: 248 AVKKVASAEIEPPSTEKFPAKIQPPLVEEATAKAEPRPAEETHVQVQPSTE------ETP 301
++ V S E ST P P+ + P PAE T + +E P
Sbjct: 814 SITPVTSPEASTLSTT--PVDSNSPVTTSTEVSSSPTPAEGTSMPTSTYSEGRTPLTSMP 871
Query: 302 DAEAATAVAENSVKVQPPPAEEAPLVEFPAEIQPPSAEESPSVELLAE--------ILPP 353
+ A + S P P+ P+ E S+ +P
Sbjct: 872 VSTTLVATSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPGEGSTPLTSMPD 931
Query: 354 SAEESPSEEPPAEILPPPAEKSPSVELLGEIRSPSAQKAPIEVQPLPAEGA--LEEAP-- 409
S S E P +P SP+ + P+EG L P
Sbjct: 932 STTPVVSSEARTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTPSEGTTPLTSTPVS 991
Query: 410 ----AKVEPPTVEETLADVQPLLPEEAPREEARELQLSTAMETPAEEAPTEFQSPLPKE- 464
A E T+ T D L T+M T P+E +PL +
Sbjct: 992 HTLVANSEASTLSTTPVDSNTPLTTSTEASSPPPTAEGTSMPT---STPSEGSTPLTRMP 1048
Query: 465 -TTAEEASAEIQLLAATEPPAD-ETPAEARSPLSEETSAEEAHAEVQSPLAEETTA-EEA 521
+T AS+E L+ T PAD TP S S ++ + + S +E +T
Sbjct: 1049 VSTTMVASSETSTLSTT--PADTSTPVTTYSQASSSSTTADGTSMPTSTYSEGSTPLTSV 1106
Query: 522 SAEIQLLAAIEAPA-DETPAEAQSPLSEETSAEEAPAEVQ------SPSAKGVSIEEAPL 574
+L+ + EA TP + P++ T A +P + SP ++G + PL
Sbjct: 1107 PVSTRLVVSSEASTLSTTPVDTSIPVTTSTEASSSPTTAEGTSIPTSPPSEGTT----PL 1162
Query: 575 ELQPPSGEETTAEEASAAIQLLAATEASAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEV 634
P S + EA+ ++ + PPP E + P E +
Sbjct: 1163 ASMPVSTTLVVSSEANTLSTTPVDSKTQVATSTEASSPPPTAEVTSMPTSTPGERSTPLT 1222
Query: 635 QPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQSLPAEETPIEE 694
P A + +P + P A P AE SLP T
Sbjct: 1223 SMPVRHTPVASSEASTLSTSPVDTSTPVTTSAETSSSPTTAEGT-----SLPTSTTSEGS 1277
Query: 695 TLAAVHSPPADDVPAEEASVDKHSPPADLLLTEEFP-----IGEASAEVSPPPSEQT 746
TL +P V SP A LLT + SP P+E T
Sbjct: 1278 TLLT-------SIPVSTTLVT--SPEASTLLTTPVDTKGPVVTSNEVSSSPTPAEGT 1325
Score = 62.8 bits (151), Expect = 1e-09
Identities = 173/849 (20%), Positives = 278/849 (32%), Gaps = 103/849 (12%)
Query: 18 AIPKSSSPKATHRIGNTSGSKGSYSAKAYESIRVSSE-------LQQTWTKRKHGQEMTS 70
++P S++ AT I S + S S S T T + +TS
Sbjct: 869 SMPVSTTLVATSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPGEGSTPLTS 928
Query: 71 KSLQTDTIVEEKKEVKLVEETVVPEEKSADVREAAIELPESVQDVEIPPNIPSVQLKMDR 130
T +V E + + T V A P + + IP + PS
Sbjct: 929 MPDSTTPVVSS--EARTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTPSEGTTPLT 986
Query: 131 SQQTSRT-----GYWTMMNIPPVEKVDKEQQTYFSESEIVV--ISRPDSSSTKSKEDALK 183
S S T T+ P T S S P S+ ++ +
Sbjct: 987 STPVSHTLVANSEASTLSTTPVDSNTPLTTSTEASSPPPTAEGTSMPTSTPSEGSTPLTR 1046
Query: 184 HKSSGKIFASEHPEFQPATNSNEEIGQKNISRTSFTQETKKGPPVLLEDELREEVTVPVV 243
S + AS T ++ S+ S + T G + E + P+
Sbjct: 1047 MPVSTTMVASSETSTLSTTPADTSTPVTTYSQASSSSTTADGTS--MPTSTYSEGSTPLT 1104
Query: 244 QEGSAVKKVASAEIEPPSTEKFPAKIQPPLVEEATAKAEPRPAEETHVQVQPSTEET--- 300
+ + V S+E ST P P+ A + P AE T + P +E T
Sbjct: 1105 SVPVSTRLVVSSEASTLSTT--PVDTSIPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPL 1162
Query: 301 ---PDAEAATAVAE-NSVKVQPPPAEEAPLVEFPAEIQPPSAEESPSVELLAEILPPSAE 356
P + +E N++ P ++ A PP+AE + P
Sbjct: 1163 ASMPVSTTLVVSSEANTLSTTPVDSKTQVATSTEASSPPPTAEVTSM-----PTSTPGER 1217
Query: 357 ESPSEEPPAEILPPPAEKSPSVELLG-EIRSPSAQKAPIEVQPLPAEGA----------- 404
+P P P + ++ ++ + +P A P AEG
Sbjct: 1218 STPLTSMPVRHTPVASSEASTLSTSPVDTSTPVTTSAETSSSPTTAEGTSLPTSTTSEGS 1277
Query: 405 --LEEAPAKVEPPTVEETLADVQPLLPEEAPREEARELQLSTAMETPAE--EAPT----E 456
L P T E + + + P + E+ S TPAE PT E
Sbjct: 1278 TLLTSIPVSTTLVTSPEASTLLTTPVDTKGPVVTSNEVSSSP---TPAEGTSMPTSTYSE 1334
Query: 457 FQSPL---PKETTAEEASAEIQLLAATE-----PPADETPAEARSPLSEETSAEEAH-AE 507
++PL P TT +SA I +L+ T P T A + SE TS ++ +E
Sbjct: 1335 GRTPLTSIPVNTTLVASSA-ISILSTTPVDNSTPVTTSTEACSSPTTSEGTSMPNSNPSE 1393
Query: 508 VQSPLAE--ETTAEEASAEIQLLAAIEAPADETPAEAQSPLSEETSAEEAPAEVQSPSAK 565
+PL +T S+E L+A TP + +P + A +P +A+
Sbjct: 1394 GTTPLTSIPVSTTPVVSSEASTLSA-------TPVDTSTPGTTSAEATSSPT-----TAE 1441
Query: 566 GVSIE-------EAPLELQPPSGEETTAEEASAAIQLLAATEASAEEAPAEVQPPPAEEA 618
G+SI + PL+ P S EAS + P + P
Sbjct: 1442 GISIPTSTPSEGKTPLKSIPVSNTPVANSEAS-----------TLSTTPVDSNSPVVTST 1490
Query: 619 PAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEA 678
P PAE + P+E + A P + A + PA P +
Sbjct: 1491 AVSSSPTPAEGTSIAIS-TPSEGSTALTSIPVSTTTVASSEINSLSTTPAVTSTPVTTYS 1549
Query: 679 PAEVQSLPAEETPIEETLAAVHSPPADDVPAEEASVDKHSPPADLLLTEEFPIGEASAEV 738
A A+ T ++ + + S P +P V S A+ L T
Sbjct: 1550 QASSSPTTADGTSMQTSTYSEGSTPLTSLPVSTMLV--VSSEANTLSTTPIDSKTQVTAS 1607
Query: 739 SPPPSEQTPEDEALVENVSTEFQSPQVAGIPAVKLGSVVLEGEAKFEEVSKINSVLKDLS 798
+ S T E ++ + +E SP + IP + V EA + ++S ++
Sbjct: 1608 TEASSSTTAEGSSMTISTPSE-GSPLLTSIPVST--TPVASPEASTLSTTPVDSNSPVIT 1664
Query: 799 NTNDGQAPT 807
+T +PT
Sbjct: 1665 STEVSSSPT 1673
Score = 61.2 bits (147), Expect = 4e-09
Identities = 120/586 (20%), Positives = 201/586 (34%), Gaps = 55/586 (9%)
Query: 252 VASAEIEPPSTEKFPAKIQPPLVEEATAKAEPRPAEETHVQV----QPSTEETPDAEAAT 307
VA++E ST P P+V + P PAE T + + + ST T + T
Sbjct: 1467 VANSEASTLSTT--PVDSNSPVVTSTAVSSSPTPAEGTSIAISTPSEGSTALTSIPVSTT 1524
Query: 308 AVAENSVKV--QPPPAEEAPLVEFPAEIQPPSAEESPSVELLA--------EILPPSAEE 357
VA + + P P+ + P+ + S++ LP S
Sbjct: 1525 TVASSEINSLSTTPAVTSTPVTTYSQASSSPTTADGTSMQTSTYSEGSTPLTSLPVSTML 1584
Query: 358 SPSEEPPAEILPPPAEKSPSVELLGEIRSPSAQKAPIEVQPLPAEGA--LEEAPAKVEPP 415
S E + P + V E S + + P+EG+ L P P
Sbjct: 1585 VVSSEANT-LSTTPIDSKTQVTASTEASSSTTAEGSSMTISTPSEGSPLLTSIPVSTTPV 1643
Query: 416 TVEETLADVQPLLPEEAPREEARELQLSTAMETPAEEAP------TEFQSPLPKET--TA 467
E + +P + E+ S TPAE TE ++PL T T
Sbjct: 1644 ASPEASTLSTTPVDSNSPVITSTEVSSSP---TPAEGTSMPTSTYTEGRTPLTSITVRTT 1700
Query: 468 EEASAEIQLLAATEPPADETPAEARSPLSEETSAEEAHAEVQSPLAEETTAEEAS--AEI 525
AS+ I L+ T P + TP + + E + S +E TT + +
Sbjct: 1701 PVASSAISTLSTT-PVDNSTPVTTSTEARSSPTTSEGTSMPNSTPSEGTTPLTSIPVSTT 1759
Query: 526 QLLAAIEAPADETPAEAQSPLSEETSAEEAPAEVQSPSAKGVSIEEAPLELQPPSGEETT 585
+L++ + TP + +P++ T A +P +A+G SI + L S T
Sbjct: 1760 PVLSSEASTLSATPIDTSTPVTTSTEATSSPT-----TAEGTSIPTSTL-----SEGMTP 1809
Query: 586 AEEASAAIQLLAATEASA-EEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPA 644
+ L+A +EAS P + P P PAE P +E + A
Sbjct: 1810 LTSTPVSHTLVANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIATSTP-SEGSTA 1868
Query: 645 EVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQSLPAEETPIEETLAAVHSPPA 704
P + A + PA P A A+ + + + PP
Sbjct: 1869 LTSIPVSTTTVASSETNTLSTTPAVTSTPVTTYAQVSSSPTTADGSSMPTSTPREGRPPL 1928
Query: 705 DDVPAEEASV--DKHSPPADLLLTEEFPIGEAS-AEVSPPPSEQTPEDEALVENVSTEFQ 761
+P +V + + + L P+ S A SP ++ T ST
Sbjct: 1929 TSIPVSTTTVASSEINTLSTTLADTRTPVTTYSQASSSPTTADGTSMPTPAYSEGSTPLT 1988
Query: 762 SPQVAGIPAVKLGSVVLEGEAKFEEVSKINSVLKDLSNTNDGQAPT 807
S ++ ++V+ EA + +++ ++T +PT
Sbjct: 1989 SMPLS-------TTLVVSSEASTLSTTPVDTSTPATTSTEGSSSPT 2027
Score = 56.6 bits (135), Expect = 9e-08
Identities = 116/580 (20%), Positives = 180/580 (31%), Gaps = 62/580 (10%)
Query: 157 TYFSESEIVVISRPDSSSTKSKEDALKHKSSGKIFASEHPEFQPATNSNEEIGQKNISRT 216
TY S ++V+S DS+ + + D P T S E T
Sbjct: 3167 TYMPVSTMLVVSSEDSTLSATPVDTST----------------PVTTSTEATSSTTAEGT 3210
Query: 217 SFTQETKKGPPVLLEDELREEVTVPVVQEGSAVKKVASAEIEPPSTEKFPAKIQPPLVEE 276
S T E P+ + VAS+E ST P PL
Sbjct: 3211 SIPTSTPS------------EGMTPLTSVPVSNTPVASSEASILSTT--PVDSNTPLTTS 3256
Query: 277 ATAKAEPRPAEETHVQVQPSTEET------PDAEAATAVAENSVKVQPPPAEEAPLVEFP 330
A + P AE T + +E + P + A +E S P P+ +
Sbjct: 3257 TEASSSPPTAEGTSMPTSTPSEGSTPLTSMPVSTTTVASSETSTLSTTPADTSTPVTTYS 3316
Query: 331 -AEIQPPSAE-ESPSVELLAEILPPSAEESPSEEPPAEILPPPAEKSPSVELLGEIRSPS 388
A PP A+ S +E P S S P +P + +P
Sbjct: 3317 QASSSPPIADGTSMPTSTYSEGSTPLTNMSFSTTPVVSSEASTLSTTPV-----DTSTPV 3371
Query: 389 AQKAPIEVQPLPAEGALEEAPAKVEPPTVEETL-ADVQPLLPEEAPREEARELQLSTAME 447
+ P AEG + E T ++ P++ E + +T +
Sbjct: 3372 TTSTEASLSPTTAEGTSIPTSSPSEGTTPLASMPVSTTPVVSSEVNTLSTTPVDSNTLVT 3431
Query: 448 TPAE--EAPTEFQ-SPLPKETTAEEASA-EIQLLAATEPPADETPAEARSPLSEETSAEE 503
T E +PT + + LP TT+E ++ I L+ T + E + +P+ T
Sbjct: 3432 TSTEASSSPTIAEGTSLPTSTTSEGSTPLSIMPLSTTPVASSEASTLSTTPVDTSTPVTT 3491
Query: 504 AHAEVQSPLAEETTAEEASAEIQLLAAIEAPADETPAEAQSPLSEETSA-EEAPAEVQSP 562
+ SP TTAE S P P S E S P + +
Sbjct: 3492 SSPTNSSP----TTAEVTSMPTSTAGEGSTPLTNMPVSTTPVASSEASTLSTTPVDSNTF 3547
Query: 563 SAKGVSIEEAPLELQPPSGEETTAEEASAAI--QLLAAT-----EASAEEAPA-EVQPPP 614
+P LQ + +T E S+++ LL++T EAS P+ + P
Sbjct: 3548 VTSSSQASSSPATLQVTTMRMSTPSEGSSSLTTMLLSSTYVTSSEASTPSTPSVDRSTPV 3607
Query: 615 AEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPP 674
+ P P E + P P + P + A P + P
Sbjct: 3608 TTSTQSNSTPTPPEVITLPMSTPSEVSTPLTIMPVSTTSVTIS-EAGTASTLPVDTSTPV 3666
Query: 675 AEEAPAEVQSLPAEETPIEETLAAVHSPPADDVPAEEASV 714
+ E T + + S P +P V
Sbjct: 3667 ITSTQVSSSPVTPEGTTMPIWTPSEGSTPLTTMPVSTTRV 3706
Score = 55.1 bits (131), Expect = 3e-07
Identities = 113/505 (22%), Positives = 168/505 (33%), Gaps = 80/505 (15%)
Query: 311 ENSVKVQPPPAEEAPLVEFPAEIQPPSAEESPSVELLAEILPPSAEESPSEEPPAEILPP 370
E+SV P + P E + S S S L P S E++ S P P
Sbjct: 95 ESSVTSDTPGVSSTRMT--PTESRTTSESTSDSTTLF----PSSTEDTSSPTTPEGTDVP 148
Query: 371 PAEKSPSVELLGEIRSPSAQKAPIEVQPLPAEGALEEAPAKVE--PPTVEETLADVQPLL 428
+ +PS E S S+ A + PLP+ A KV+ P T A P
Sbjct: 149 MS--TPSEE------SISSTMAFVSTAPLPSFEAYTSLTYKVDMSTPLTTSTQASSSPTT 200
Query: 429 PEEAPREEARELQLST--------AMETPAEEA------PTEFQSP--LPKETTAEEASA 472
PE ++ + ST M+ + EA P E +P + + ++ +A
Sbjct: 201 PESTTIPKSTNSEGSTPLTSMPASTMKVASSEAITLLTTPVEISTPVTISAQASSSPTTA 260
Query: 473 EIQLLAATEPPADETPAEARSPLS-------EETSAEEAHAEVQSPL-------AEETTA 518
E L+ + P TP R PLS E ++ A P+ + TTA
Sbjct: 261 EGPSLSNSAPSGGSTPL-TRMPLSVMLVVSSEASTLSTTPAATNIPVITSTEASSSPTTA 319
Query: 519 EEASAEIQLLAAIEAPADETPAEAQSPLSEETSAEE-APAEVQSPSAKGVSIEEAPLELQ 577
E S P TPA + E S P + + P +
Sbjct: 320 EGTSIPTSTYTEGSTPLTSTPASTMPVATSEMSTLSITPVDTSTLVTTSTEPSSLPTTAE 379
Query: 578 PPSGEETTAEEASAAIQ-------LLAATEASAEEA-PAEVQPPPAEEAPAEVQPPPAEE 629
S +T E S + L+A++EAS P + + + A P AE+
Sbjct: 380 ATSMLTSTLSEGSTPLTNMPVSTILVASSEASTTSTIPVDSKTFVTTASEASSSPTTAED 439
Query: 630 APAEVQPP-----PAEEAPAEVQPPPAEEA------PAEVQPPPAEEAPAEVQPPPAEEA 678
P P P P + EA P + + A PP
Sbjct: 440 TSIATSTPSEGSTPLTSMPVSTTPVASSEASNLSTTPVDSKTQVTTSTEASSSPP----- 494
Query: 679 PAEVQSLPAEETPIEETLAAVHSPPADDVPAEEASVDKHSPPADLLLTEEFPIGEASAEV 738
AEV S+P T S V + EAS +P + P+ +S
Sbjct: 495 TAEVNSMPTSTPSEGSTPLTSMSVSTMPVASSEASTLSTTP-----VDTSTPVTTSSEAS 549
Query: 739 SPPPSEQTPEDEALVENVSTEFQSP 763
S S TPE ++ + +E +P
Sbjct: 550 S---SSTTPEGTSIPTSTPSEGSTP 571
Score = 33.1 bits (74), Expect = 1.1
Identities = 38/176 (21%), Positives = 59/176 (33%), Gaps = 16/176 (9%)
Query: 252 VASAEIEPPSTEKFPAKIQPPLVEEATAKAEPRPAEETHVQVQ--PSTEETPDAEAATAV 309
+ S E+ PST +E T A A T+V + PST T T+
Sbjct: 3966 ITSTELNTPSTSSSSTTTSFSTTKEFTTPAMTTAAPLTYVTMSTAPSTPRTTSRGCTTSA 4025
Query: 310 AENSVKVQPPPAEEAPLVEFPAEIQP--PSAEESPSVELLAEILPPSAEESPSEEPPAEI 367
+ S A P +P PS+E S + + +PP+ + S PP
Sbjct: 4026 STLS-------ATSTPHTSTSVTTRPVTPSSESSRPSTITSHTIPPTFPPAHSSTPPTTS 4078
Query: 368 LPPPAEKSPSVELLGEIRSPSAQKA---PIEVQPLPAEGALEEAPAKVEPPTVEET 420
+V + PS + + +P ++ P PTV T
Sbjct: 4079 ASSTTVNPEAVTTMTTRTKPSTRTTSFPTVTTTAVPTNTTIKSNPTST--PTVPRT 4132
>gi|239740955 PREDICTED: similar to c114 SLIT-like testicular
protein isoform 1 [Homo sapiens]
Length = 1635
Score = 80.1 bits (196), Expect = 8e-15
Identities = 158/699 (22%), Positives = 266/699 (38%), Gaps = 127/699 (18%)
Query: 149 EKVDKEQQTYFSESEIVVISRPDSSSTKSKEDALKHKSSGKIF--ASEHPEFQPATNSNE 206
+K+ K+ +S +EI+ I R S+ K+ SS S PE + S+E
Sbjct: 148 KKLKKDPAQRWSLAEIIGIIRQLSTPQSQKQTLQNEYSSTDTPYPGSLPPELR--VKSDE 205
Query: 207 EIG-QKNISRTSFTQETKKGPPVLLEDELREEVTVPVVQEGSAVKKVASAEIEPPSTEKF 265
G + + + F E + P LED + S++++ A A++ P E+
Sbjct: 206 PPGPSEQVGPSQFHLEPETQNPETLEDI-----------QSSSLQQEAPAQL-PQLLEEE 253
Query: 266 PAKIQ---PPLVEEATAKAEPRPAEETHVQVQ---------PSTEETPDAEAATAVAENS 313
P+ +Q P L E++ ++ P E VQ P+ P T +E +
Sbjct: 254 PSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPT 313
Query: 314 VKVQPPPAEEAPLVEFPAEIQPPSAEE----SPSVELLAEILPPSAEESPSE--EPPAEI 367
+ + A++ ++FP E++P + ++ P V + L S ++ P + E P E+
Sbjct: 314 NETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQQQPVQPSESPREV 373
Query: 368 LPPPAEKS---------------PSVELLGEIRSPSAQKAPIEVQ-PLPAEGALE----- 406
P ++ P + SPS P +VQ + AE + E
Sbjct: 374 ESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSL 433
Query: 407 ---EAPAK-------VEPPTVEETLADVQPLLPEEAPREEARELQLSTAMETP-----AE 451
EA + VEPP ++ PLLPE + +Q T+ ++P
Sbjct: 434 VHQEATTRLSGSGNDVEPPAIQH---GGPPLLPESSEEAGPLAVQQETSFQSPEPINNEN 490
Query: 452 EAPTEFQSPLPKETTAEEASA------------EIQLLAATEPPADETPAEAR-SPLS-E 497
+PT+ ++ TAEE + E + +PP +A PL
Sbjct: 491 PSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLG 550
Query: 498 ETSAEEAHAEVQ-SPLAEETTAEEASAEIQLLAAIEAPADETPA--EAQSPLSEETSAE- 553
T E+ EV+ SP +ET + + L + + TP +AQ P+S + +
Sbjct: 551 FTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQL 610
Query: 554 ---------EAPAEV---QSPSAKGVSIEEAPLELQPPSGEETTAEEAS-AAIQLLAATE 600
E EV P VS + + L P +T + A +Q L
Sbjct: 611 LDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGF 670
Query: 601 ASAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAE-VQPPPAEEAPAEVQ 659
++ EV+P A A PPP EV PP+++ A+ A P +++
Sbjct: 671 TITPKSMTEVEPSTALMTTA---PPPGH---PEVTLPPSDKGQAQHSHLTQATVQPLDLE 724
Query: 660 PPPAEEAPAEVQP-PPAEEAPAEVQSLPAEETPIEETLAAVHSPPADDVPAEEASVDKHS 718
+ EV+P P EE + L P E T HS + A
Sbjct: 725 LTITTKPTTEVKPSPTTEETSTQPPDLGLAIIP-EPTTETGHSTALEKTTA--------- 774
Query: 719 PPADLLLTEEFPIGEASAEVSPPPSEQTPEDEALVENVS 757
P D + T + + EV+ PP+E P ++LV++ S
Sbjct: 775 PRPDRVQT----LHRSLTEVTGPPTELEPAQDSLVQSES 809
Score = 66.2 bits (160), Expect = 1e-10
Identities = 114/480 (23%), Positives = 182/480 (37%), Gaps = 84/480 (17%)
Query: 318 PPPAEEAPLVEFPAEIQPPSAEESPSVELLAEILPPSAEESPSEEPPAEILPPPAEKSPS 377
PP + FP E P A P+ + L PSA S E PA PP E + +
Sbjct: 56 PPEPWSSHSSHFPRE--SPHAPTLPADPWDFDHLGPSA----SSEMPA----PPQESTEN 105
Query: 378 VELLGEIRSPSAQKAPIEVQPLPAEGALEEAPAKVEPPTVEETLADVQPLLPEEAPREEA 437
+ + SA + P+E + A + ++ K+ P +E L P+ P++ ++ A
Sbjct: 106 LVPFLDTWD-SAGELPLEPEQFLA--SQQDLKDKLSP---QERL----PVSPKKLKKDPA 155
Query: 438 RELQLSTAMETPAEEAPTEFQSPLPKETTAEEASAEIQLLAATEPPADETPAEARSPLSE 497
+ L+ + + + + Q K+T E S+ + PP ++ SE
Sbjct: 156 QRWSLAEIIGIIRQLSTPQSQ----KQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSE 211
Query: 498 ETSAEEAHAE--VQSPLAEETTAEEASAEIQLLAAIEAPADETPAEAQSPLSEETSA--E 553
+ + H E Q+P ET + S+ +Q E PA+ L EE S+ +
Sbjct: 212 QVGPSQFHLEPETQNP---ETLEDIQSSSLQ---------QEAPAQLPQLLEEEPSSMQQ 259
Query: 554 EAPAEVQSPSAKGVSIEEAPLELQPPSGEET-------TAEEASAAIQLLAA----TEAS 602
EAPA S + +++ + +QPP ++ T + A + + + TE+S
Sbjct: 260 EAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPTNETESS 319
Query: 603 AEEA------PAEVQPPPA-EEAPAEVQPPPAE---EAPAEVQPPPAEEAPAEVQPPPAE 652
+ P EV+P +EAP E PP E + QP E+P EV+ P +
Sbjct: 320 QAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQQQPVQPSESPREVESSPTQ 379
Query: 653 EAPAEVQP--------PPAEEAPAEVQPPPAEEAPAEVQSLPAEETPIEETLAAVHSPPA 704
+ P PP + P P +VQ A E E + VH
Sbjct: 380 QETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEAT 439
Query: 705 DDVPAEEASVDKHSPPADLLLTEEFPIGEASAEVSPPPSEQTPEDEALVENVSTEFQSPQ 764
+ V+ PPA I + P SE E L T FQSP+
Sbjct: 440 TRLSGSGNDVE---PPA---------IQHGGPPLLPESSE---EAGPLAVQQETSFQSPE 484
>gi|239740953 PREDICTED: similar to c114 SLIT-like testicular
protein isoform 2 [Homo sapiens]
Length = 1700
Score = 80.1 bits (196), Expect = 8e-15
Identities = 158/699 (22%), Positives = 266/699 (38%), Gaps = 127/699 (18%)
Query: 149 EKVDKEQQTYFSESEIVVISRPDSSSTKSKEDALKHKSSGKIF--ASEHPEFQPATNSNE 206
+K+ K+ +S +EI+ I R S+ K+ SS S PE + S+E
Sbjct: 148 KKLKKDPAQRWSLAEIIGIIRQLSTPQSQKQTLQNEYSSTDTPYPGSLPPELR--VKSDE 205
Query: 207 EIG-QKNISRTSFTQETKKGPPVLLEDELREEVTVPVVQEGSAVKKVASAEIEPPSTEKF 265
G + + + F E + P LED + S++++ A A++ P E+
Sbjct: 206 PPGPSEQVGPSQFHLEPETQNPETLEDI-----------QSSSLQQEAPAQL-PQLLEEE 253
Query: 266 PAKIQ---PPLVEEATAKAEPRPAEETHVQVQ---------PSTEETPDAEAATAVAENS 313
P+ +Q P L E++ ++ P E VQ P+ P T +E +
Sbjct: 254 PSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPT 313
Query: 314 VKVQPPPAEEAPLVEFPAEIQPPSAEE----SPSVELLAEILPPSAEESPSE--EPPAEI 367
+ + A++ ++FP E++P + ++ P V + L S ++ P + E P E+
Sbjct: 314 NETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQQQPVQPSESPREV 373
Query: 368 LPPPAEKS---------------PSVELLGEIRSPSAQKAPIEVQ-PLPAEGALE----- 406
P ++ P + SPS P +VQ + AE + E
Sbjct: 374 ESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSL 433
Query: 407 ---EAPAK-------VEPPTVEETLADVQPLLPEEAPREEARELQLSTAMETP-----AE 451
EA + VEPP ++ PLLPE + +Q T+ ++P
Sbjct: 434 VHQEATTRLSGSGNDVEPPAIQH---GGPPLLPESSEEAGPLAVQQETSFQSPEPINNEN 490
Query: 452 EAPTEFQSPLPKETTAEEASA------------EIQLLAATEPPADETPAEAR-SPLS-E 497
+PT+ ++ TAEE + E + +PP +A PL
Sbjct: 491 PSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLG 550
Query: 498 ETSAEEAHAEVQ-SPLAEETTAEEASAEIQLLAAIEAPADETPA--EAQSPLSEETSAE- 553
T E+ EV+ SP +ET + + L + + TP +AQ P+S + +
Sbjct: 551 FTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQL 610
Query: 554 ---------EAPAEV---QSPSAKGVSIEEAPLELQPPSGEETTAEEAS-AAIQLLAATE 600
E EV P VS + + L P +T + A +Q L
Sbjct: 611 LDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGF 670
Query: 601 ASAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAE-VQPPPAEEAPAEVQ 659
++ EV+P A A PPP EV PP+++ A+ A P +++
Sbjct: 671 TITPKSMTEVEPSTALMTTA---PPPGH---PEVTLPPSDKGQAQHSHLTQATVQPLDLE 724
Query: 660 PPPAEEAPAEVQP-PPAEEAPAEVQSLPAEETPIEETLAAVHSPPADDVPAEEASVDKHS 718
+ EV+P P EE + L P E T HS + A
Sbjct: 725 LTITTKPTTEVKPSPTTEETSTQPPDLGLAIIP-EPTTETGHSTALEKTTA--------- 774
Query: 719 PPADLLLTEEFPIGEASAEVSPPPSEQTPEDEALVENVS 757
P D + T + + EV+ PP+E P ++LV++ S
Sbjct: 775 PRPDRVQT----LHRSLTEVTGPPTELEPAQDSLVQSES 809
Score = 66.2 bits (160), Expect = 1e-10
Identities = 114/480 (23%), Positives = 182/480 (37%), Gaps = 84/480 (17%)
Query: 318 PPPAEEAPLVEFPAEIQPPSAEESPSVELLAEILPPSAEESPSEEPPAEILPPPAEKSPS 377
PP + FP E P A P+ + L PSA S E PA PP E + +
Sbjct: 56 PPEPWSSHSSHFPRE--SPHAPTLPADPWDFDHLGPSA----SSEMPA----PPQESTEN 105
Query: 378 VELLGEIRSPSAQKAPIEVQPLPAEGALEEAPAKVEPPTVEETLADVQPLLPEEAPREEA 437
+ + SA + P+E + A + ++ K+ P +E L P+ P++ ++ A
Sbjct: 106 LVPFLDTWD-SAGELPLEPEQFLA--SQQDLKDKLSP---QERL----PVSPKKLKKDPA 155
Query: 438 RELQLSTAMETPAEEAPTEFQSPLPKETTAEEASAEIQLLAATEPPADETPAEARSPLSE 497
+ L+ + + + + Q K+T E S+ + PP ++ SE
Sbjct: 156 QRWSLAEIIGIIRQLSTPQSQ----KQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSE 211
Query: 498 ETSAEEAHAE--VQSPLAEETTAEEASAEIQLLAAIEAPADETPAEAQSPLSEETSA--E 553
+ + H E Q+P ET + S+ +Q E PA+ L EE S+ +
Sbjct: 212 QVGPSQFHLEPETQNP---ETLEDIQSSSLQ---------QEAPAQLPQLLEEEPSSMQQ 259
Query: 554 EAPAEVQSPSAKGVSIEEAPLELQPPSGEET-------TAEEASAAIQLLAA----TEAS 602
EAPA S + +++ + +QPP ++ T + A + + + TE+S
Sbjct: 260 EAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPTNETESS 319
Query: 603 AEEA------PAEVQPPPA-EEAPAEVQPPPAE---EAPAEVQPPPAEEAPAEVQPPPAE 652
+ P EV+P +EAP E PP E + QP E+P EV+ P +
Sbjct: 320 QAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQQQPVQPSESPREVESSPTQ 379
Query: 653 EAPAEVQP--------PPAEEAPAEVQPPPAEEAPAEVQSLPAEETPIEETLAAVHSPPA 704
+ P PP + P P +VQ A E E + VH
Sbjct: 380 QETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEAT 439
Query: 705 DDVPAEEASVDKHSPPADLLLTEEFPIGEASAEVSPPPSEQTPEDEALVENVSTEFQSPQ 764
+ V+ PPA I + P SE E L T FQSP+
Sbjct: 440 TRLSGSGNDVE---PPA---------IQHGGPPLLPESSE---EAGPLAVQQETSFQSPE 484
>gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo sapiens]
Length = 2462
Score = 80.1 bits (196), Expect = 8e-15
Identities = 163/741 (21%), Positives = 266/741 (35%), Gaps = 134/741 (18%)
Query: 40 SYSAKAYESIRVSSELQQTWTKRKHGQEMTSKSLQTDTIVEEKKEVKLVEETVVPEEKSA 99
+Y + S R + QQ +++ Q+ + + EEK E + +E EEK
Sbjct: 478 NYKSLVRRSYRRRGKSQQQQQQQQQQQQQQQQQPMPRSSQEEKDEKEKEKEAEKEEEKPE 537
Query: 100 DVREAAIELPESVQDVEIPPNIPSVQL----KMDRSQQTSRTGYWT--MMNIPPVEK-VD 152
+ L E D N + + + Q R G T M N E+ +
Sbjct: 538 VENDKEDLLKEKTDDTSGEDNDEKEAVASKGRKTANSQGRRKGRITRSMANEANSEEAIT 597
Query: 153 KEQQTYFSESEIVVISR-PDSSSTKSKEDALKHKSSGKIFASEHPEFQPATNSNEEIGQK 211
+Q + E+ SR + +K+ L+H + A +G K
Sbjct: 598 PQQSAELASMELNESSRWTEEEMETAKKGLLEHGRNWSAIA-------------RMVGSK 644
Query: 212 NISRT-SFTQETKKGPPVLLEDELREEVTVPVVQEGSAVKKVASAEIEPPSTEKFPAKIQ 270
+S+ +F KK + DE+ ++ + + +E +A +K A FP ++
Sbjct: 645 TVSQCKNFYFNYKKRQNL---DEILQQHKLKMEKERNARRKKKKAPAAASEEAAFPPVVE 701
Query: 271 PPLVEEATAKA-EPRPAEETHVQVQPSTEE----TPDAEAATAVAENSVKVQPPPAEEAP 325
+E + E EE V S++ +P EAA +N K PPA
Sbjct: 702 DEEMEASGVSGNEEEMVEEAEATVNNSSDTESIPSPHTEAAKDTGQNGPK---PPAT--- 755
Query: 326 LVEFPAEIQPPSAEESPSVELLAEILPPSAEESPSEEPPAEILPPPAEKSPSVELLGEIR 385
A+ PP PP+ PP E +P P E +P+ E G
Sbjct: 756 ---LGADGPPPG--------------PPT--------PPPEDIPAPTEPTPASEATG--- 787
Query: 386 SPSAQKAPIEVQPLPAEGALEEAPAKVEPPTVEETLADVQPLLPEEAPREEARELQLSTA 445
+P+ AP P+ PP P++P+E EE TA
Sbjct: 788 APTPPPAP---------------PSPSAPP----------PVVPKEEKEEE-------TA 815
Query: 446 METPAEEAPTEFQSPLPKETTAEEASAEIQLLAATEPPADETPAEARSPLSEETSAEEA- 504
P EE E + P +E + AE + + A+E PA+ + + E +AE A
Sbjct: 816 AAPPVEEG-EEQKPPAAEELAVDTGKAEEPVKSECTEEAEEGPAKGKDAEAAEATAEGAL 874
Query: 505 -HAEVQSPLAEETTAEEASAEIQLLAAIEAPADETPAEAQSPLSEETSAEEAPAEVQSPS 563
+ + TTA+ + A ++ ADE EA+ + +
Sbjct: 875 KAEKKEGGSGRATTAKSSGAPQDSDSSATCSADEVD-EAEGGDKNRLLSPRPSLLTPTGD 933
Query: 564 AKGVSIEEAPLELQPPSGEETTAEEASAAIQLLAATEASAEEAPAEVQPPPAEEAPAEVQ 623
+ + + PL+L+ ++ +AAI + T +V PP E+A
Sbjct: 934 PRANASPQKPLDLK-------QLKQRAAAIPPIQVT---------KVHEPPREDAAPTKP 977
Query: 624 PPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAE---EAP-------AEVQPP 673
PPA P +QP E+ A QP + + PPA+ E P AE Q
Sbjct: 978 APPAPPPPQNLQP----ESDAPQQPGSSPRGKSRSPAPPADKEAEKPVFFPAFAAEAQKL 1033
Query: 674 PAEEAPAEVQSLPAEETPIEETLAAVHSPPADDVPAEEASVDKHSPPADLLLTEEFPIGE 733
P + P LP P E A+ H+P D A + H P L T +
Sbjct: 1034 PG-DPPCWTSGLPFPVPPREVIKASPHAP---DPSAFSYAPPGHPLPLGLHDTARPVLPR 1089
Query: 734 ASAEVSPPPSEQTPEDEALVE 754
+PPP + + +++E
Sbjct: 1090 PPTISNPPPLISSAKHPSVLE 1110
Score = 37.0 bits (84), Expect = 0.075
Identities = 54/242 (22%), Positives = 82/242 (33%), Gaps = 30/242 (12%)
Query: 461 LPKETTAEEASAEIQLLAATEPPADETPAEARSPLSEETSAEEAHAEVQSPLAEETTAEE 520
L K TT + E + D +S L+ T+ E HA + P E+++
Sbjct: 1776 LTKPTTTSSSERERD----RDRERDRDREREKSILTSTTTVE--HAPIWRPGTEQSSGSS 1829
Query: 521 ASAEIQLLAAIEAPADETPAEAQSPLSEET--SAEEAPAEVQSPSAKGV----------- 567
S+ + PA + A SP+S T + ++ P+ + + KG+
Sbjct: 1830 GSSGGGG-GSSSRPASHSHAHQHSPISPRTQDALQQRPSVLHNTGMKGIITAVEPSTPTV 1888
Query: 568 ------SIEEAPLELQPPSGEETTAEEASAAIQLLAATEASAEEAPAEVQP--PPAEEAP 619
S P PP+ L +EAP +P P A+
Sbjct: 1889 LRSTSTSSPVRPAATFPPATHCPLGGTLDGVYPTLMEPVLLPKEAPRVARPERPRADTGH 1948
Query: 620 AEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQP-PPAEEA 678
A + PPA P P + PP + A + P AP P PPA A
Sbjct: 1949 AFLAKPPARSGLEPASSPSKGSEPRPLVPPVSGHATI-ARTPAKNLAPHHASPDPPAPPA 2007
Query: 679 PA 680
A
Sbjct: 2008 SA 2009
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 79.7 bits (195), Expect = 1e-14
Identities = 125/551 (22%), Positives = 185/551 (33%), Gaps = 90/551 (16%)
Query: 256 EIEPPSTEKFPAKIQPPLVEEATAKAEPRPAEETHVQVQPSTE-----ETPDAEAATAVA 310
E PP+ P + P T + P + + + + E P A +A A
Sbjct: 92 ERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGA 151
Query: 311 ENSVKVQPPPAEEAPLV---------EFPAEIQPPSAEESPSVELLAEILPPSAEESPSE 361
P P +P + E PSA P E + + ++E S +E
Sbjct: 152 RRDTS-GPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTE 210
Query: 362 EPPAEILPPPAEKSPSVELLGEIRSPSAQKAPIEVQPLPAEGALEEAPAKVEPPTVEETL 421
PA A + PS G ++ P+++ PL +PA+ P
Sbjct: 211 PSPA------ARRRPSAG--GGLQRPASRSLSSSATPL-------SSPARSGPSARGTPR 255
Query: 422 ADVQPLLPEEAPREEARELQLSTAMETPAEEAPTEFQSPL--PKETTAEEASAEIQLLAA 479
A P P+ + R Q++ + A SPL P + SA L
Sbjct: 256 APAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTL 315
Query: 480 TEPPADETPAEARSPLSEETSAEEAHAEVQSP-LAEETTAEEASAEIQLLAAIEAPADET 538
PPA P++A + L T + H+ + SP L+ T + L ++AP
Sbjct: 316 PSPPATP-PSQATTSLGSPT-LQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPP 373
Query: 539 PAEAQSPLSEETSAEEAPAEVQSPSAKGVSIEEAPLE----------LQPPSGEETT--A 586
+ SPL A Q+P+A V + +AP PP+ + A
Sbjct: 374 ASPPLSPL--------ATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSA 425
Query: 587 EEASAAIQLLAATEASAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEV 646
S A LAA +P P P PPP P ++ PP + PA
Sbjct: 426 TPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALA 485
Query: 647 QPP------PAEEAPAEVQPPPAEEAPAEVQPPPAEEAP----AEVQSLPAEETPIEETL 696
PP P P + P+ P P +AP A + +P P TL
Sbjct: 486 TPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVP-PSPPASPTL 544
Query: 697 AAVHSPPADDVPAEEASVDKHSPPADLLLTEEFPIGEASAEVSPPPSEQTPEDEALVENV 756
A PP P + SV P L L A PPP ++P
Sbjct: 545 QAPRRPP---TPGPDTSVS--GPRLTLAL----------APGPPPPPSRSP--------- 580
Query: 757 STEFQSPQVAG 767
S+ P +AG
Sbjct: 581 SSTLSGPDLAG 591
Score = 65.9 bits (159), Expect = 2e-10
Identities = 103/439 (23%), Positives = 153/439 (34%), Gaps = 49/439 (11%)
Query: 237 EVTVPVVQEGSAVKKVASAEIEPPSTEKFPAKIQPPLVEEATAKAEPRPAEETHVQVQPS 296
+VT P A+ ++S+ + PS P+ PP ++ + P++ T P+
Sbjct: 275 QVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPT 334
Query: 297 TEETPDAEAATAVAENSVKVQPPPAEEAPLVEFPAEIQPPSAEESPSVELLAEILPPS-- 354
+ T + ++ + PP + P + P PPS SP + LA P +
Sbjct: 335 LQATHSFLPSPPLS----PLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPN 390
Query: 355 --------AEESPSEEPPAEI-LPPPAEK--SPSVELLGEIRSPSAQKAPIEVQPLPAEG 403
A SP PP + PPA SPS + PS P++V P P
Sbjct: 391 ALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQ-APPSLAAPPLQVPPSP-PA 448
Query: 404 ALEEAPAKVEPPTVEETLADVQPLLPEEAPREEARELQLSTAMETPAEEAPTEFQSPLPK 463
+ +P+ PP LA PL + P + L P+ A Q+P
Sbjct: 449 SPPMSPSATPPPQAPPPLA-APPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPF-- 505
Query: 464 ETTAEEASAEIQLLAATEPPADETPAEARSPLSEETSAEEAHAEVQSPLAEETTAEEASA 523
SA + + PP P A +PL + + A +Q+P T + S
Sbjct: 506 -----SPSASLPMSPLATPPPQAPPVLA-APLLQVPPSPPASPTLQAPRRPPTPGPDTSV 559
Query: 524 EIQLLAAIEAPADETPAEAQSPLSEETSAEEAPAEVQSPSAKGVSIEEAPLELQPPSGEE 583
L AP P ++SP S + + A S SA E + P G
Sbjct: 560 SGPRLTLALAPG-PPPPPSRSPSSTLSGPDLAG---HSSSATSTPEELRGYDSGPEGG-- 613
Query: 584 TTAEEASAAIQLLAATEASAEEAPAEVQPPPA-EEAPAEVQPPPAEEAPAEVQ------- 635
A +L A A+ PA PP A AP P P P
Sbjct: 614 -AAASPPPDAELAACHPAAWSRGPA---PPLAFRGAPGAPLPWPPATGPGSADGLCTIYE 669
Query: 636 ---PPPAEEAPAEVQPPPA 651
P A AP + P P+
Sbjct: 670 TEGPESATPAPGALDPGPS 688
>gi|239745855 PREDICTED: hypothetical protein XP_002343606 [Homo
sapiens]
Length = 870
Score = 79.7 bits (195), Expect = 1e-14
Identities = 161/714 (22%), Positives = 268/714 (37%), Gaps = 157/714 (21%)
Query: 149 EKVDKEQQTYFSESEIVVISRPDSSSTKSKEDALKHKSSGKIFASEHPEFQPA---TNSN 205
+K+ K+ +S +EI+ I+R S+ K+ SS + +P P S+
Sbjct: 148 KKLKKDPAQRWSLAEIIGIARQLSTPQSQKQTLQNEYSSTD---TPYPSSLPPELRVKSD 204
Query: 206 EEIG-QKNISRTSFTQETKKGPPVLLEDELREEVTVPVVQEGSAVKKVASAEIEPPSTEK 264
E G + + + F E + P LED + S++++ A A++ P E+
Sbjct: 205 EPPGPSEQVGPSQFHLEPETQNPETLEDI-----------QSSSLQQEAPAQL-PQLLEE 252
Query: 265 FPAKIQ---PPLVEEATAKAEPRPAEETHVQVQ---------PSTEETPDAEAATAVAEN 312
P+ +Q P L E++ ++ P E VQ P+ P T +E
Sbjct: 253 EPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEP 312
Query: 313 SVKVQPPPAEEAPLVEFPAEIQPPSAEE----SPSVELLAEILPPSAEESP--------- 359
+ + + A++ ++FP E++P + ++ P V + L S ++ P
Sbjct: 313 TNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVSPMEHELSISEQQQPVQPSESSRE 372
Query: 360 ------SEEPPAEILPPPAEKSPSVELLG-----EIRSPSAQKAPIEVQ-PLPAEGALE- 406
+E P + PP +V G + SPS P +VQ + AE + E
Sbjct: 373 VESSLTQQETPGQ---PPEHHEVTVSPPGHHQTHHLDSPSVSVKPPDVQLTIAAEPSAEV 429
Query: 407 -------EAPAK-------VEPPTVEETLADVQPLLPEEAPREEARELQLSTAMETP--- 449
EA A+ VEPP ++ PLLPE + +Q T+ ++P
Sbjct: 430 GTSLVHQEATARLSGSGNDVEPPAIQH---GGPPLLPESSEEAGPLAVQQETSFQSPEPI 486
Query: 450 --AEEAPTEFQSPLPKETTAEEASA------------EIQLLAATEPPADETPAEAR-SP 494
+PT+ ++ TAEE + E + +PP +A P
Sbjct: 487 NNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQP 546
Query: 495 LS-EETSAEEAHAEVQ-SPLAEETTAEEASAEIQLLAAIEAPADETPA--EAQSPLSEET 550
L T E+ EV+ SP +ET + + L + + TP +AQ P+S
Sbjct: 547 LDLGFTITPESMTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSV 606
Query: 551 SAE----------EAPAEV---QSPSAKGVSIEEAPLELQPPSGEETTAEEAS-AAIQLL 596
+ + E EV +P VS + + L P +T + A +Q L
Sbjct: 607 TVQLLDLGLTITPEPTTEVGHSTAPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPL 666
Query: 597 AATEASAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAE--------VQP 648
++ EV+P A A PPP EV PP+++ A+ VQP
Sbjct: 667 DLGFTITPKSMTEVEPSTALMTTA---PPPGH---PEVTLPPSDKGQAQHSHLTQATVQP 720
Query: 649 PPAE-----EAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQSLPAEETPIEETLAAVHSPP 703
E + EV+P P E QPP + + P ET L +P
Sbjct: 721 LDLELTITTKPTTEVKPSPTTE-ETSTQPP---DLGLAIIPEPTTETGHSTALEKTTAPH 776
Query: 704 ADDVPAEEASVDKHSPPADLLLTEEFPIGEASAEVSPPPSEQTPEDEALVENVS 757
D V + S+ EV+ PP+E P ++LV++ S
Sbjct: 777 PDRVQSLHRSL---------------------TEVTGPPTELEPAQDSLVQSES 809
Score = 50.4 bits (119), Expect = 7e-06
Identities = 85/336 (25%), Positives = 129/336 (38%), Gaps = 53/336 (15%)
Query: 443 STAMETPAEEAPTEFQSPLPKETTAEEASAEI-QLLAATEPPADETPAEARSPLSEETSA 501
S+ M P +E+ L +A E E Q LA+ + D+ + R P+S +
Sbjct: 92 SSEMPAPPQESTENLVPFLDTWDSAGEQPLEPEQFLASQQDLKDKLSPQERLPVSPKKLK 151
Query: 502 EEAHAEVQSPLAEETTAEEASAEIQLLAAIEAPADETPAEAQSPLSEETSAEEAPAEVQS 561
++ P + AE QL TP + L E S+ + P
Sbjct: 152 KD-------PAQRWSLAEIIGIARQL---------STPQSQKQTLQNEYSSTDTPYPSSL 195
Query: 562 PSAKGVSIEEAPLELQPPSGEETTAEEASAAIQLLAATEASA--EEAPAEVQPPPAEEAP 619
P V +E P + + E + + L ++S+ +EAPA++ P EE P
Sbjct: 196 PPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQL-PQLLEEEP 254
Query: 620 AEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEA----------PAE 669
+ +Q +EAPA PP E+ E P E VQPP ++A PA+
Sbjct: 255 SSMQ----QEAPA--LPP---ESSMESLTLPNHEV--SVQPPGEDQAYYHLPNITVKPAD 303
Query: 670 VQPPPAEEAPAEVQSLPA-EETPIEETLAAVHSPPADDVPAEEASVDKHSPPADLLLTEE 728
V+ E E +S A +ETPI+ S + P E PP + E
Sbjct: 304 VEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIE--------PPVS-PMEHE 354
Query: 729 FPIGEASAEVSPPPSEQTPEDEALVENVSTEFQSPQ 764
I E V PSE + E E+ + T Q P+
Sbjct: 355 LSISEQQQPVQ--PSESSREVESSLTQQETPGQPPE 388
>gi|242117953 SH3 domain-containing protein C1orf113 isoform 1 [Homo
sapiens]
Length = 756
Score = 79.3 bits (194), Expect = 1e-14
Identities = 123/511 (24%), Positives = 188/511 (36%), Gaps = 115/511 (22%)
Query: 250 KKVASAEIEPPSTEK--FPAKIQPPLVEEATAKAEPRPAEETHVQVQPSTEETPDAEAAT 307
+KV S E P K P P + + ATA P A+ + + S + T
Sbjct: 249 RKVVSRESAPIKEPKKLMPKTSLPTVKKLATATTGPSKAKTSRTPSRDSQKLTSRDSGPN 308
Query: 308 AVAENSVKVQPPPAEEAPLVEFPAEIQPPSAEESPSVELLAEILPPSAEESPSEEPPAEI 367
++ P + + P + S EE S + A PS + +P + A
Sbjct: 309 GGFQSGGSYHP--GRKRSKTQTPQQRSVSSQEEEHSSPVKA----PSVKRTPMPDKTATP 362
Query: 368 LPPPAEKSPSVELLGEIRSPSAQKAPIEVQPLPAEGALEEAPAKVEPPTVEETLADVQPL 427
PPA ++ +PS++K P AP KV P TL D +
Sbjct: 363 ERPPAPEN----------APSSKKIP--------------APDKVPSPEKTLTLGDKASI 398
Query: 428 ----------LPEEAPREEARELQLSTAMETPAEEAPTEFQSPLPKET-TAEEASAEIQL 476
P++ P E M TP ++A S +P+ET T ++ S ++
Sbjct: 399 PGNSTSGKIPAPDKVPTPEK--------MVTPEDKASIPENSIIPEETLTVDKPSTPERV 450
Query: 477 LAATE------PPADETPAEARSPLSEETSAEEAHAEVQSP-LAEET------------T 517
+ E PP D+ P +PL +E E +V +P L+EE +
Sbjct: 451 FSVEESPALEAPPMDKVPNPKMAPLGDEAPTLE---KVLTPELSEEEVSTRDDIQFHHFS 507
Query: 518 AEEASAEIQLLAAIEAPADETPAEAQSPLSEETSAEEAPAEVQSPSAKGVSIEEAPLELQ 577
+EEA +++ A E P+ + EE EAP Q
Sbjct: 508 SEEALQKVKYFVAKEDPSSQ----------EEAHTPEAPPP------------------Q 539
Query: 578 PPSGEETTAEEASAAIQ-----LLAATEASAEEAPAEVQPPP-------AEEAPAEVQPP 625
PPS E E ++ A ++ PA +P P EEAP+ +
Sbjct: 540 PPSSERCLGEMKCTLVRGDSSPRQAELKSGPASRPALEKPHPHEEATTLPEEAPSNDERT 599
Query: 626 PAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQSL 685
P EEAP Q P EE + EE + + PP EE + + PP E A A+ ++
Sbjct: 600 PEEEAPPNEQRPLREEVLPKEGVASKEEVTLKEELPPKEEVAPKEEVPPIERAFAQ-KTR 658
Query: 686 PAEETP-IEETLAAVHSPPADDVPAEEASVD 715
P + P +ETLA P + + VD
Sbjct: 659 PIKPPPDSQETLALPSLVPQNYTENKNEGVD 689
Score = 64.3 bits (155), Expect = 4e-10
Identities = 112/486 (23%), Positives = 183/486 (37%), Gaps = 69/486 (14%)
Query: 13 KKKHMAIPKSSSPKATHRIGNTSGSKGSYSAKAYESIRVSSELQQTWTKRKHGQEMTSKS 72
K K P S K T R +G G S +Y R S+ Q + QE S
Sbjct: 286 KAKTSRTPSRDSQKLTSRDSGPNG--GFQSGGSYHPGRKRSKTQTPQQRSVSSQEEEHSS 343
Query: 73 LQTDTIVEEKKEVKLVEETVVPEEKSADVREAAIELPESVQDVEIPPNIPSVQLKMDRSQ 132
+ V+ T +P++ + R A E S + + P +PS + +
Sbjct: 344 ---------PVKAPSVKRTPMPDKTATPERPPAPENAPSSKKIPAPDKVPSPEKTLTLGD 394
Query: 133 QTSRTGYWTMMNIPPVEKVDKEQQTYFSESEIVVISRPDSSSTKSKEDAL-KHKSSGKIF 191
+ S G T IP +KV ++ E + S P++S + + K + ++F
Sbjct: 395 KASIPGNSTSGKIPAPDKVPTPEKMVTPEDK---ASIPENSIIPEETLTVDKPSTPERVF 451
Query: 192 ASEHPEFQPATNSNEEIGQKNISRTSFTQET----KKGPPVLLEDEL--REEVTVPVVQE 245
+ E PA + N E K P L E+E+ R+++
Sbjct: 452 SVEE---SPALEAPPMDKVPNPKMAPLGDEAPTLEKVLTPELSEEEVSTRDDIQFHHFSS 508
Query: 246 GSAVKKV------------------ASAEIEPPSTEKFPAKIQPPLV------EEATAKA 281
A++KV + +PPS+E+ +++ LV +A K+
Sbjct: 509 EEALQKVKYFVAKEDPSSQEEAHTPEAPPPQPPSSERCLGEMKCTLVRGDSSPRQAELKS 568
Query: 282 EP--RPAEETHVQVQPSTEETPDAEAATAVAENSVKVQPPPAEEAPLVEFPAEIQPPSAE 339
P RPA E + P E T E A + E + + + PP E+ PL E E+ P
Sbjct: 569 GPASRPALE---KPHPHEEATTLPEEAPSNDERTPEEEAPPNEQRPLRE---EVLPKEGV 622
Query: 340 ESPSVELLAEILPPSAEESPSEE-PPAE---------ILPPP-AEKSPSVELLGEIRSPS 388
S L E LPP E +P EE PP E I PPP ++++ ++ L
Sbjct: 623 ASKEEVTLKEELPPKEEVAPKEEVPPIERAFAQKTRPIKPPPDSQETLALPSLVPQNYTE 682
Query: 389 AQKAPIEVQPLPAEGALEEAPAKVEPPTVEETLADVQPLLPEEAPREEARELQLSTAMET 448
+ ++V L E ++ +E L D+ L E +E+ R L++ T
Sbjct: 683 NKNEGVDVTSLRGEVESLRRALELMEVQLERKLTDIWEELKSE--KEQRRRLEVQVMQGT 740
Query: 449 PAEEAP 454
+ P
Sbjct: 741 QKSQTP 746
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.299 0.119 0.316
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 39,705,447
Number of Sequences: 37866
Number of extensions: 2542870
Number of successful extensions: 49301
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 637
Number of HSP's successfully gapped in prelim test: 1962
Number of HSP's that attempted gapping in prelim test: 14409
Number of HSP's gapped (non-prelim): 14061
length of query: 825
length of database: 18,247,518
effective HSP length: 111
effective length of query: 714
effective length of database: 14,044,392
effective search space: 10027695888
effective search space used: 10027695888
T: 11
A: 40
X1: 17 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.