Guide to the Human Genome
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Search of human proteins with 209862789

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|209862789 microtubule associated monoxygenase, calponin and
LIM domain containing 3 isoform 1 [Homo sapiens]
         (2002 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|209862789 microtubule associated monoxygenase, calponin and L...  3985   0.0  
gi|170172518 microtubule associated monoxygenase, calponin and L...  1873   0.0  
gi|209862793 microtubule associated monoxygenase, calponin and L...  1494   0.0  
gi|7662284 microtubule associated monoxygenase, calponin and LIM...   997   0.0  
gi|205360947 microtubule associated monoxygenase, calponin and L...   730   0.0  
gi|226530313 microtubule associated monoxygenase, calponin and L...   388   e-107
gi|118918413 MICAL C-terminal like [Homo sapiens]                     205   3e-52
gi|33667117 MICAL-like 2 isoform 1 [Homo sapiens]                     147   8e-35
gi|31324577 molecule interacting with Rab13 [Homo sapiens]            123   2e-27
gi|217330570 EH domain binding protein 1 isoform 2 [Homo sapiens]     108   7e-23
gi|217330568 EH domain binding protein 1 isoform 1 [Homo sapiens]     108   7e-23
gi|217330574 EH domain binding protein 1 isoform 3 [Homo sapiens]     105   3e-22
gi|217330572 EH domain binding protein 1 isoform 3 [Homo sapiens]     105   3e-22
gi|55741677 SET domain containing 1A [Homo sapiens]                   104   1e-21
gi|67782321 spectrin beta isoform a [Homo sapiens]                    103   1e-21
gi|67782319 spectrin beta isoform b [Homo sapiens]                    103   1e-21
gi|210032580 SET domain containing 1B [Homo sapiens]                  102   5e-21
gi|150378549 tangerin [Homo sapiens]                                  101   8e-21
gi|5902122 spectrin, beta, non-erythrocytic 2 [Homo sapiens]          100   1e-20
gi|112382252 spectrin, beta, non-erythrocytic 1 isoform 2 [Homo ...    98   7e-20
gi|112382250 spectrin, beta, non-erythrocytic 1 isoform 1 [Homo ...    98   7e-20
gi|4501893 actinin, alpha 2 [Homo sapiens]                             97   2e-19
gi|4557241 actinin, alpha 3 [Homo sapiens]                             96   5e-19
gi|194097352 actinin, alpha 1 isoform c [Homo sapiens]                 95   8e-19
gi|194097350 actinin, alpha 1 isoform a [Homo sapiens]                 95   8e-19
gi|4501891 actinin, alpha 1 isoform b [Homo sapiens]                   95   8e-19
gi|115430237 spectrin, beta, non-erythrocytic 4 isoform sigma1 [...    94   1e-18
gi|12025678 actinin, alpha 4 [Homo sapiens]                            92   7e-18
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]         92   7e-18
gi|75750474 spectrin domain with coiled-coils 1 NSP5a3b [Homo sa...    91   9e-18

>gi|209862789 microtubule associated monoxygenase, calponin and LIM
            domain containing 3 isoform 1 [Homo sapiens]
          Length = 2002

 Score = 3985 bits (10335), Expect = 0.0
 Identities = 2002/2002 (100%), Positives = 2002/2002 (100%)

Query: 1    MEERKHETMNPAHVLFDRFVQATTCKGTLKAFQELCDHLELKPKDYRSFYHKLKSKLNYW 60
            MEERKHETMNPAHVLFDRFVQATTCKGTLKAFQELCDHLELKPKDYRSFYHKLKSKLNYW
Sbjct: 1    MEERKHETMNPAHVLFDRFVQATTCKGTLKAFQELCDHLELKPKDYRSFYHKLKSKLNYW 60

Query: 61   KAKALWAKLDKRGSHKDYKKGKACTNTKCLIIGAGPCGLRTAIDLSLLGAKVVVIEKRDA 120
            KAKALWAKLDKRGSHKDYKKGKACTNTKCLIIGAGPCGLRTAIDLSLLGAKVVVIEKRDA
Sbjct: 61   KAKALWAKLDKRGSHKDYKKGKACTNTKCLIIGAGPCGLRTAIDLSLLGAKVVVIEKRDA 120

Query: 121  FSRNNVLHLWPFTIHDLRGLGAKKFYGKFCAGAIDHISIRQLQLILLKVALILGIEIHVN 180
            FSRNNVLHLWPFTIHDLRGLGAKKFYGKFCAGAIDHISIRQLQLILLKVALILGIEIHVN
Sbjct: 121  FSRNNVLHLWPFTIHDLRGLGAKKFYGKFCAGAIDHISIRQLQLILLKVALILGIEIHVN 180

Query: 181  VEFQGLIQPPEDQENERIGWRALVHPKTHPVSEYEFEVIIGGDGRRNTLEGFRRKEFRGK 240
            VEFQGLIQPPEDQENERIGWRALVHPKTHPVSEYEFEVIIGGDGRRNTLEGFRRKEFRGK
Sbjct: 181  VEFQGLIQPPEDQENERIGWRALVHPKTHPVSEYEFEVIIGGDGRRNTLEGFRRKEFRGK 240

Query: 241  LAIAITANFINRNTTAEAKVEEISGVAFIFNQKFFQELREATGIDLENIVYYKDDTHYFV 300
            LAIAITANFINRNTTAEAKVEEISGVAFIFNQKFFQELREATGIDLENIVYYKDDTHYFV
Sbjct: 241  LAIAITANFINRNTTAEAKVEEISGVAFIFNQKFFQELREATGIDLENIVYYKDDTHYFV 300

Query: 301  MTAKKQSLLDKGVILHDYADTELLLSRENVDQEALLSYAREAADFSTQQQLPSLDFAINH 360
            MTAKKQSLLDKGVILHDYADTELLLSRENVDQEALLSYAREAADFSTQQQLPSLDFAINH
Sbjct: 301  MTAKKQSLLDKGVILHDYADTELLLSRENVDQEALLSYAREAADFSTQQQLPSLDFAINH 360

Query: 361  YGQPDVAMFDFTCMYASENAALVREQNGHQLLVALVGDSLLEPFWPMGTGIARGFLAAMD 420
            YGQPDVAMFDFTCMYASENAALVREQNGHQLLVALVGDSLLEPFWPMGTGIARGFLAAMD
Sbjct: 361  YGQPDVAMFDFTCMYASENAALVREQNGHQLLVALVGDSLLEPFWPMGTGIARGFLAAMD 420

Query: 421  SAWMVRSWSLGTSPLEVLAERESIYRLLPQTTPENVSKNFSQYSIDPVTRYPNINVNFLR 480
            SAWMVRSWSLGTSPLEVLAERESIYRLLPQTTPENVSKNFSQYSIDPVTRYPNINVNFLR
Sbjct: 421  SAWMVRSWSLGTSPLEVLAERESIYRLLPQTTPENVSKNFSQYSIDPVTRYPNINVNFLR 480

Query: 481  PSQVRHLYDTGETKDIHLEMESLVNSRTTPKLTRNESVARSSKLLGWCQRQTDGYAGVNV 540
            PSQVRHLYDTGETKDIHLEMESLVNSRTTPKLTRNESVARSSKLLGWCQRQTDGYAGVNV
Sbjct: 481  PSQVRHLYDTGETKDIHLEMESLVNSRTTPKLTRNESVARSSKLLGWCQRQTDGYAGVNV 540

Query: 541  TDLTMSWKSGLALCAIIHRYRPDLIDFDSLDEQNVEKNNQLAFDIAEKELGISPIMTGKE 600
            TDLTMSWKSGLALCAIIHRYRPDLIDFDSLDEQNVEKNNQLAFDIAEKELGISPIMTGKE
Sbjct: 541  TDLTMSWKSGLALCAIIHRYRPDLIDFDSLDEQNVEKNNQLAFDIAEKELGISPIMTGKE 600

Query: 601  MASVGEPDKLSMVMYLTQFYEMFKDSLPSSDTLDLNAEEKAVLIASTRSPISFLSKLGQT 660
            MASVGEPDKLSMVMYLTQFYEMFKDSLPSSDTLDLNAEEKAVLIASTRSPISFLSKLGQT
Sbjct: 601  MASVGEPDKLSMVMYLTQFYEMFKDSLPSSDTLDLNAEEKAVLIASTRSPISFLSKLGQT 660

Query: 661  ISRKRSPKDKKEKDLDGAGKRRKTSQSEEEEAPRGHRGERPTLVSTLTDRRMDVAVGNQN 720
            ISRKRSPKDKKEKDLDGAGKRRKTSQSEEEEAPRGHRGERPTLVSTLTDRRMDVAVGNQN
Sbjct: 661  ISRKRSPKDKKEKDLDGAGKRRKTSQSEEEEAPRGHRGERPTLVSTLTDRRMDVAVGNQN 720

Query: 721  KVKYMATQLLAKFEENAPAQSIGIRRQGSMKKEFPQNLGGSDTCYFCQKRVYVMERLSAE 780
            KVKYMATQLLAKFEENAPAQSIGIRRQGSMKKEFPQNLGGSDTCYFCQKRVYVMERLSAE
Sbjct: 721  KVKYMATQLLAKFEENAPAQSIGIRRQGSMKKEFPQNLGGSDTCYFCQKRVYVMERLSAE 780

Query: 781  GKFFHRSCFKCEYCATTLRLSAYAYDIEDGKFYCKPHYCYRLSGYAQRKRPAVAPLSGKE 840
            GKFFHRSCFKCEYCATTLRLSAYAYDIEDGKFYCKPHYCYRLSGYAQRKRPAVAPLSGKE
Sbjct: 781  GKFFHRSCFKCEYCATTLRLSAYAYDIEDGKFYCKPHYCYRLSGYAQRKRPAVAPLSGKE 840

Query: 841  AKGPLQDGATTDANGRANAVASSTERTPGSGVNGLEEPSIAKRLRGTPERIELENYRLSL 900
            AKGPLQDGATTDANGRANAVASSTERTPGSGVNGLEEPSIAKRLRGTPERIELENYRLSL
Sbjct: 841  AKGPLQDGATTDANGRANAVASSTERTPGSGVNGLEEPSIAKRLRGTPERIELENYRLSL 900

Query: 901  RQAEALQEVPEETQAEHNLSSVLDTGAEEDVASSSSESEMEEEGEEEEEEPRLPPSDLGG 960
            RQAEALQEVPEETQAEHNLSSVLDTGAEEDVASSSSESEMEEEGEEEEEEPRLPPSDLGG
Sbjct: 901  RQAEALQEVPEETQAEHNLSSVLDTGAEEDVASSSSESEMEEEGEEEEEEPRLPPSDLGG 960

Query: 961  VPWKEAVRIHALLKGKSEEELEASKSFGPGNEEEEEEEEEYEEEEEEDYDEEEEESSEAG 1020
            VPWKEAVRIHALLKGKSEEELEASKSFGPGNEEEEEEEEEYEEEEEEDYDEEEEESSEAG
Sbjct: 961  VPWKEAVRIHALLKGKSEEELEASKSFGPGNEEEEEEEEEYEEEEEEDYDEEEEESSEAG 1020

Query: 1021 NQRLQQVMHAADPLEIQADVHWTHIREREEEERMAPASESSASGAPLDENDLEEDVDSEP 1080
            NQRLQQVMHAADPLEIQADVHWTHIREREEEERMAPASESSASGAPLDENDLEEDVDSEP
Sbjct: 1021 NQRLQQVMHAADPLEIQADVHWTHIREREEEERMAPASESSASGAPLDENDLEEDVDSEP 1080

Query: 1081 AEIEGEAAEDGDPGDTGAELDDDQHWSDSPSDADRELRLPCPAEGEAELELRVSEDEEKL 1140
            AEIEGEAAEDGDPGDTGAELDDDQHWSDSPSDADRELRLPCPAEGEAELELRVSEDEEKL
Sbjct: 1081 AEIEGEAAEDGDPGDTGAELDDDQHWSDSPSDADRELRLPCPAEGEAELELRVSEDEEKL 1140

Query: 1141 PASPKHQERGPSQATSPIRSPQESALLFIPVHSPSTEGPQLPPVPAATQEKSPEERLFPE 1200
            PASPKHQERGPSQATSPIRSPQESALLFIPVHSPSTEGPQLPPVPAATQEKSPEERLFPE
Sbjct: 1141 PASPKHQERGPSQATSPIRSPQESALLFIPVHSPSTEGPQLPPVPAATQEKSPEERLFPE 1200

Query: 1201 PLLPKEKPKADAPSDLKAVHSPIRSQPVTLPEARTPVSPGSPQPQPPVAASTPPPSPLPI 1260
            PLLPKEKPKADAPSDLKAVHSPIRSQPVTLPEARTPVSPGSPQPQPPVAASTPPPSPLPI
Sbjct: 1201 PLLPKEKPKADAPSDLKAVHSPIRSQPVTLPEARTPVSPGSPQPQPPVAASTPPPSPLPI 1260

Query: 1261 CSQPQPSTEATVPSPTQSPIRFQPAPAKTSTPLAPLPVQSQSDTKDRLGSPLAVDEALRR 1320
            CSQPQPSTEATVPSPTQSPIRFQPAPAKTSTPLAPLPVQSQSDTKDRLGSPLAVDEALRR
Sbjct: 1261 CSQPQPSTEATVPSPTQSPIRFQPAPAKTSTPLAPLPVQSQSDTKDRLGSPLAVDEALRR 1320

Query: 1321 SDLVEEFWMKSAEIRRSLGLTPVDRSKGPEPSFPTPAFRPVSLKSYSVEKSPQDEGLHLL 1380
            SDLVEEFWMKSAEIRRSLGLTPVDRSKGPEPSFPTPAFRPVSLKSYSVEKSPQDEGLHLL
Sbjct: 1321 SDLVEEFWMKSAEIRRSLGLTPVDRSKGPEPSFPTPAFRPVSLKSYSVEKSPQDEGLHLL 1380

Query: 1381 KPLSIPKRLGLPKPEGEPLSLPTPRSPSDRELRSAQEERRELSSSSGLGLHGSSSNMKTL 1440
            KPLSIPKRLGLPKPEGEPLSLPTPRSPSDRELRSAQEERRELSSSSGLGLHGSSSNMKTL
Sbjct: 1381 KPLSIPKRLGLPKPEGEPLSLPTPRSPSDRELRSAQEERRELSSSSGLGLHGSSSNMKTL 1440

Query: 1441 GSQSFNTSDSAMLTPPSSPPPPPPPGEEPATLRRKLREAEPNASVVPPPLPATWMRPPRE 1500
            GSQSFNTSDSAMLTPPSSPPPPPPPGEEPATLRRKLREAEPNASVVPPPLPATWMRPPRE
Sbjct: 1441 GSQSFNTSDSAMLTPPSSPPPPPPPGEEPATLRRKLREAEPNASVVPPPLPATWMRPPRE 1500

Query: 1501 PAQPPREEVRKSFVESVEEIPFADDVEDTYDDKTEDSSLQEKFFTPPSCWPRPEKPRHPP 1560
            PAQPPREEVRKSFVESVEEIPFADDVEDTYDDKTEDSSLQEKFFTPPSCWPRPEKPRHPP
Sbjct: 1501 PAQPPREEVRKSFVESVEEIPFADDVEDTYDDKTEDSSLQEKFFTPPSCWPRPEKPRHPP 1560

Query: 1561 LAKENGRLPALEGTLQPQKRGLPLVSAEAKELAEERMRAREKSVKSQALRDAMARQLSRM 1620
            LAKENGRLPALEGTLQPQKRGLPLVSAEAKELAEERMRAREKSVKSQALRDAMARQLSRM
Sbjct: 1561 LAKENGRLPALEGTLQPQKRGLPLVSAEAKELAEERMRAREKSVKSQALRDAMARQLSRM 1620

Query: 1621 QQMELASGAPRPRKASSAPSQGKERRPDSPTRPTLRGSEEPTLKHEATSEEVLSPPSDSG 1680
            QQMELASGAPRPRKASSAPSQGKERRPDSPTRPTLRGSEEPTLKHEATSEEVLSPPSDSG
Sbjct: 1621 QQMELASGAPRPRKASSAPSQGKERRPDSPTRPTLRGSEEPTLKHEATSEEVLSPPSDSG 1680

Query: 1681 GPDGSFTSSEGSSGKSKKRSSLFSPRRNKKEKKSKGEGRPPEKPSSNLLEEAAAKPKSLW 1740
            GPDGSFTSSEGSSGKSKKRSSLFSPRRNKKEKKSKGEGRPPEKPSSNLLEEAAAKPKSLW
Sbjct: 1681 GPDGSFTSSEGSSGKSKKRSSLFSPRRNKKEKKSKGEGRPPEKPSSNLLEEAAAKPKSLW 1740

Query: 1741 KSVFSGYKKDKKKKADDKSCPSTPSSGATVDSGKHRVLPVVRAELQLRRQLSFSEDSDLS 1800
            KSVFSGYKKDKKKKADDKSCPSTPSSGATVDSGKHRVLPVVRAELQLRRQLSFSEDSDLS
Sbjct: 1741 KSVFSGYKKDKKKKADDKSCPSTPSSGATVDSGKHRVLPVVRAELQLRRQLSFSEDSDLS 1800

Query: 1801 SDDVLEKSSQKSRREPRTYTEEELNAKLTRRVQKAARRQAKQEELKRLHRAQIIQRQLQQ 1860
            SDDVLEKSSQKSRREPRTYTEEELNAKLTRRVQKAARRQAKQEELKRLHRAQIIQRQLQQ
Sbjct: 1801 SDDVLEKSSQKSRREPRTYTEEELNAKLTRRVQKAARRQAKQEELKRLHRAQIIQRQLQQ 1860

Query: 1861 VEERQRRLEERGVAVEKALRGEAGMGKKDDPKLMQEWFKLVQEKNAMVRYESELMIFARE 1920
            VEERQRRLEERGVAVEKALRGEAGMGKKDDPKLMQEWFKLVQEKNAMVRYESELMIFARE
Sbjct: 1861 VEERQRRLEERGVAVEKALRGEAGMGKKDDPKLMQEWFKLVQEKNAMVRYESELMIFARE 1920

Query: 1921 LELEDRQSRLQQELRERMAVEDHLKTEEELSEEKQILNEMLEVVEQRDSLVALLEEQRLR 1980
            LELEDRQSRLQQELRERMAVEDHLKTEEELSEEKQILNEMLEVVEQRDSLVALLEEQRLR
Sbjct: 1921 LELEDRQSRLQQELRERMAVEDHLKTEEELSEEKQILNEMLEVVEQRDSLVALLEEQRLR 1980

Query: 1981 EREEDKDLEAAMLSKGFSLNWS 2002
            EREEDKDLEAAMLSKGFSLNWS
Sbjct: 1981 EREEDKDLEAAMLSKGFSLNWS 2002


>gi|170172518 microtubule associated monoxygenase, calponin and LIM
           domain containing 3 isoform 3 [Homo sapiens]
          Length = 966

 Score = 1873 bits (4851), Expect = 0.0
 Identities = 940/963 (97%), Positives = 942/963 (97%), Gaps = 4/963 (0%)

Query: 1   MEERKHETMNPAHVLFDRFVQATTCKGTLKAFQELCDHLELKPKDYRSFYHKLKSKLNYW 60
           MEERKHETMNPAHVLFDRFVQATTCKGTLKAFQELCDHLELKPKDYRSFYHKLKSKLNYW
Sbjct: 1   MEERKHETMNPAHVLFDRFVQATTCKGTLKAFQELCDHLELKPKDYRSFYHKLKSKLNYW 60

Query: 61  KAKALWAKLDKRGSHKDYKKGKACTNTKCLIIGAGPCGLRTAIDLSLLGAKVVVIEKRDA 120
           KAKALWAKLDKRGSHKDYKKGKACTNTKCLIIGAGPCGLRTAIDLSLLGAKVVVIEKRDA
Sbjct: 61  KAKALWAKLDKRGSHKDYKKGKACTNTKCLIIGAGPCGLRTAIDLSLLGAKVVVIEKRDA 120

Query: 121 FSRNNVLHLWPFTIHDLRGLGAKKFYGKFCAGAIDHISIRQLQLILLKVALILGIEIHVN 180
           FSRNNVLHLWPFTIHDLRGLGAKKFYGKFCAGAIDHISIRQLQLILLKVALILGIEIHVN
Sbjct: 121 FSRNNVLHLWPFTIHDLRGLGAKKFYGKFCAGAIDHISIRQLQLILLKVALILGIEIHVN 180

Query: 181 VEFQGLIQPPEDQENERIGWRALVHPKTHPVSEYEFEVIIGGDGRRNTLEGFRRKEFRGK 240
           VEFQGLIQPPEDQENERIGWRALVHPKTHPVSEYEFEVIIGGDGRRNTLEGFRRKEFRGK
Sbjct: 181 VEFQGLIQPPEDQENERIGWRALVHPKTHPVSEYEFEVIIGGDGRRNTLEGFRRKEFRGK 240

Query: 241 LAIAITANFINRNTTAEAKVEEISGVAFIFNQKFFQELREATGIDLENIVYYKDDTHYFV 300
           LAIAITANFINRNTTAEAKVEEISGVAFIFNQKFFQELREATGIDLENIVYYKDDTHYFV
Sbjct: 241 LAIAITANFINRNTTAEAKVEEISGVAFIFNQKFFQELREATGIDLENIVYYKDDTHYFV 300

Query: 301 MTAKKQSLLDKGVILHDYADTELLLSRENVDQEALLSYAREAADFSTQQQLPSLDFAINH 360
           MTAKKQSLLDKGVILHDYADTELLLSRENVDQEALLSYAREAADFSTQQQLPSLDFAINH
Sbjct: 301 MTAKKQSLLDKGVILHDYADTELLLSRENVDQEALLSYAREAADFSTQQQLPSLDFAINH 360

Query: 361 YGQPDVAMFDFTCMYASENAALVREQNGHQLLVALVGDSLLEPFWPMGTGIARGFLAAMD 420
           YGQPDVAMFDFTCMYASENAALVREQNGHQLLVALVGDSLLEPFWPMGTGIARGFLAAMD
Sbjct: 361 YGQPDVAMFDFTCMYASENAALVREQNGHQLLVALVGDSLLEPFWPMGTGIARGFLAAMD 420

Query: 421 SAWMVRSWSLGTSPLEVLAERESIYRLLPQTTPENVSKNFSQYSIDPVTRYPNINVNFLR 480
           SAWMVRSWSLGTSPLEVLAERESIYRLLPQTTPENVSKNFSQYSIDPVTRYPNINVNFLR
Sbjct: 421 SAWMVRSWSLGTSPLEVLAERESIYRLLPQTTPENVSKNFSQYSIDPVTRYPNINVNFLR 480

Query: 481 PSQVRHLYDTGETKDIHLEMESLVNSRTTPKLTRNESVARSSKLLGWCQRQTDGYAGVNV 540
           PSQVRHLYDTGETKDIHLEMESLVNSRTTPKLTRNESVARSSKLLGWCQRQTDGYAGVNV
Sbjct: 481 PSQVRHLYDTGETKDIHLEMESLVNSRTTPKLTRNESVARSSKLLGWCQRQTDGYAGVNV 540

Query: 541 TDLTMSWKSGLALCAIIHRYRPDLIDFDSLDEQNVEKNNQLAFDIAEKELGISPIMTGKE 600
           TDLTMSWKSGLALCAIIHRYRPDLIDFDSLDEQNVEKNNQLAFDIAEKELGISPIMTGKE
Sbjct: 541 TDLTMSWKSGLALCAIIHRYRPDLIDFDSLDEQNVEKNNQLAFDIAEKELGISPIMTGKE 600

Query: 601 MASVGEPDKLSMVMYLTQFYEMFKDSLPSSDTLDLNAEEKAVLIASTRSPISFLSKLGQT 660
           MASVGEPDKLSMVMYLTQFYEMFKDSLPSSDTLDLNAEEKAVLIASTRSPISFLSKLGQT
Sbjct: 601 MASVGEPDKLSMVMYLTQFYEMFKDSLPSSDTLDLNAEEKAVLIASTRSPISFLSKLGQT 660

Query: 661 ISRKRSPKDKKEKDLDGAGKRRKTSQSEEEEAPRGHRGERPTLVSTLTDRRMDVAVGNQN 720
           ISRKRSPKDKKEKDLDGAGKRRKTSQSEEEEAPRGHRGERPTLVSTLTDRRMDVAVGNQN
Sbjct: 661 ISRKRSPKDKKEKDLDGAGKRRKTSQSEEEEAPRGHRGERPTLVSTLTDRRMDVAVGNQN 720

Query: 721 KVKYMATQLLAKFEENAPAQSIGIRRQGSMKKEFPQNLGGSDTCYFCQKRVYVMERLSAE 780
           KVKYMATQLLAKFEENAPAQSIGIRRQGSMKKEFPQNLGGSDTCYFCQKRVYVMERLSAE
Sbjct: 721 KVKYMATQLLAKFEENAPAQSIGIRRQGSMKKEFPQNLGGSDTCYFCQKRVYVMERLSAE 780

Query: 781 GKFFHRSCFKCEYCATTLRLSAYAYDIEDGKFYCKPHYCYRLSGYAQRKRPAVAPLSGKE 840
           GKFFHRSCFKCEYCATTLRLSAYAYDIEDGKFYCKPHYCYRLSGYAQRKRPAVAPLSGKE
Sbjct: 781 GKFFHRSCFKCEYCATTLRLSAYAYDIEDGKFYCKPHYCYRLSGYAQRKRPAVAPLSGKE 840

Query: 841 AKGPLQDGATTDANGRANAVASSTERTPGSGVNGLEEPSIAKRLRGTPERIELENYRLSL 900
           AKGPLQDGATTDANGRANAVASSTERTPGSGVNGLEEPSIAKRLRGTPERIELENYRLSL
Sbjct: 841 AKGPLQDGATTDANGRANAVASSTERTPGSGVNGLEEPSIAKRLRGTPERIELENYRLSL 900

Query: 901 RQAEALQEVPEETQAEHNLSSVLDTGAEEDVASSSSES----EMEEEGEEEEEEPRLPPS 956
           RQAEALQEVPEETQAEHNLSSVLDTGAEEDVAS    S     M      +   P  PP+
Sbjct: 901 RQAEALQEVPEETQAEHNLSSVLDTGAEEDVASRDWVSPWLPRMVSNSWAQMIHPPQPPT 960

Query: 957 DLG 959
            LG
Sbjct: 961 VLG 963


>gi|209862793 microtubule associated monoxygenase, calponin and LIM
           domain containing 3 isoform 2 [Homo sapiens]
          Length = 1073

 Score = 1494 bits (3869), Expect = 0.0
 Identities = 748/752 (99%), Positives = 749/752 (99%)

Query: 1   MEERKHETMNPAHVLFDRFVQATTCKGTLKAFQELCDHLELKPKDYRSFYHKLKSKLNYW 60
           MEERKHETMNPAHVLFDRFVQATTCKGTLKAFQELCDHLELKPKDYRSFYHKLKSKLNYW
Sbjct: 1   MEERKHETMNPAHVLFDRFVQATTCKGTLKAFQELCDHLELKPKDYRSFYHKLKSKLNYW 60

Query: 61  KAKALWAKLDKRGSHKDYKKGKACTNTKCLIIGAGPCGLRTAIDLSLLGAKVVVIEKRDA 120
           KAKALWAKLDKRGSHKDYKKGKACTNTKCLIIGAGPCGLRTAIDLSLLGAKVVVIEKRDA
Sbjct: 61  KAKALWAKLDKRGSHKDYKKGKACTNTKCLIIGAGPCGLRTAIDLSLLGAKVVVIEKRDA 120

Query: 121 FSRNNVLHLWPFTIHDLRGLGAKKFYGKFCAGAIDHISIRQLQLILLKVALILGIEIHVN 180
           FSRNNVLHLWPFTIHDLRGLGAKKFYGKFCAGAIDHISIRQLQLILLKVALILGIEIHVN
Sbjct: 121 FSRNNVLHLWPFTIHDLRGLGAKKFYGKFCAGAIDHISIRQLQLILLKVALILGIEIHVN 180

Query: 181 VEFQGLIQPPEDQENERIGWRALVHPKTHPVSEYEFEVIIGGDGRRNTLEGFRRKEFRGK 240
           VEFQGLIQPPEDQENERIGWRALVHPKTHPVSEYEFEVIIGGDGRRNTLEGFRRKEFRGK
Sbjct: 181 VEFQGLIQPPEDQENERIGWRALVHPKTHPVSEYEFEVIIGGDGRRNTLEGFRRKEFRGK 240

Query: 241 LAIAITANFINRNTTAEAKVEEISGVAFIFNQKFFQELREATGIDLENIVYYKDDTHYFV 300
           LAIAITANFINRNTTAEAKVEEISGVAFIFNQKFFQELREATGIDLENIVYYKDDTHYFV
Sbjct: 241 LAIAITANFINRNTTAEAKVEEISGVAFIFNQKFFQELREATGIDLENIVYYKDDTHYFV 300

Query: 301 MTAKKQSLLDKGVILHDYADTELLLSRENVDQEALLSYAREAADFSTQQQLPSLDFAINH 360
           MTAKKQSLLDKGVILHDYADTELLLSRENVDQEALLSYAREAADFSTQQQLPSLDFAINH
Sbjct: 301 MTAKKQSLLDKGVILHDYADTELLLSRENVDQEALLSYAREAADFSTQQQLPSLDFAINH 360

Query: 361 YGQPDVAMFDFTCMYASENAALVREQNGHQLLVALVGDSLLEPFWPMGTGIARGFLAAMD 420
           YGQPDVAMFDFTCMYASENAALVREQNGHQLLVALVGDSLLEPFWPMGTGIARGFLAAMD
Sbjct: 361 YGQPDVAMFDFTCMYASENAALVREQNGHQLLVALVGDSLLEPFWPMGTGIARGFLAAMD 420

Query: 421 SAWMVRSWSLGTSPLEVLAERESIYRLLPQTTPENVSKNFSQYSIDPVTRYPNINVNFLR 480
           SAWMVRSWSLGTSPLEVLAERESIYRLLPQTTPENVSKNFSQYSIDPVTRYPNINVNFLR
Sbjct: 421 SAWMVRSWSLGTSPLEVLAERESIYRLLPQTTPENVSKNFSQYSIDPVTRYPNINVNFLR 480

Query: 481 PSQVRHLYDTGETKDIHLEMESLVNSRTTPKLTRNESVARSSKLLGWCQRQTDGYAGVNV 540
           PSQVRHLYDTGETKDIHLEMESLVNSRTTPKLTRNESVARSSKLLGWCQRQTDGYAGVNV
Sbjct: 481 PSQVRHLYDTGETKDIHLEMESLVNSRTTPKLTRNESVARSSKLLGWCQRQTDGYAGVNV 540

Query: 541 TDLTMSWKSGLALCAIIHRYRPDLIDFDSLDEQNVEKNNQLAFDIAEKELGISPIMTGKE 600
           TDLTMSWKSGLALCAIIHRYRPDLIDFDSLDEQNVEKNNQLAFDIAEKELGISPIMTGKE
Sbjct: 541 TDLTMSWKSGLALCAIIHRYRPDLIDFDSLDEQNVEKNNQLAFDIAEKELGISPIMTGKE 600

Query: 601 MASVGEPDKLSMVMYLTQFYEMFKDSLPSSDTLDLNAEEKAVLIASTRSPISFLSKLGQT 660
           MASVGEPDKLSMVMYLTQFYEMFKDSLPSSDTLDLNAEEKAVLIASTRSPISFLSKLGQT
Sbjct: 601 MASVGEPDKLSMVMYLTQFYEMFKDSLPSSDTLDLNAEEKAVLIASTRSPISFLSKLGQT 660

Query: 661 ISRKRSPKDKKEKDLDGAGKRRKTSQSEEEEAPRGHRGERPTLVSTLTDRRMDVAVGNQN 720
           ISRKRSPKDKKEKDLDGAGKRRKTSQSEEEEAPRGHRGERPTLVSTLTDRRMDVAVGNQN
Sbjct: 661 ISRKRSPKDKKEKDLDGAGKRRKTSQSEEEEAPRGHRGERPTLVSTLTDRRMDVAVGNQN 720

Query: 721 KVKYMATQLLAKFEENAPAQSIGIRRQGSMKK 752
           KVKYMATQLLAKFEENAPAQSIGIRRQ   K+
Sbjct: 721 KVKYMATQLLAKFEENAPAQSIGIRRQQREKE 752



 Score =  267 bits (682), Expect = 9e-71
 Identities = 141/215 (65%), Positives = 156/215 (72%), Gaps = 18/215 (8%)

Query: 671 KEKDLDGAGKRRKTSQSEEEEAPRG------------HRGERPTLVSTLTDRRMDVAV-- 716
           ++ D D  GK+    +  E E PR                 RP   S+ + R+  + +  
Sbjct: 783 RDLDADNRGKQSPHHERPEPEPPRRFFVDQWELSLSLRSSARPASPSSDSLRQKYIKMYT 842

Query: 717 -GNQNKVKYMATQLLAKFEENAPAQSIGIRRQGSMKKEFPQNLGGSDTCYFCQKRVYVME 775
            G  +  + +A QL  K +   P   +  +  GSMKKEFPQNLGGSDTCYFCQKRVYVME
Sbjct: 843 GGVSSLAEQIANQLQRKEQ---PKALLDKKELGSMKKEFPQNLGGSDTCYFCQKRVYVME 899

Query: 776 RLSAEGKFFHRSCFKCEYCATTLRLSAYAYDIEDGKFYCKPHYCYRLSGYAQRKRPAVAP 835
           RLSAEGKFFHRSCFKCEYCATTLRLSAYAYDIEDGKFYCKPHYCYRLSGYAQRKRPAVAP
Sbjct: 900 RLSAEGKFFHRSCFKCEYCATTLRLSAYAYDIEDGKFYCKPHYCYRLSGYAQRKRPAVAP 959

Query: 836 LSGKEAKGPLQDGATTDANGRANAVASSTERTPGS 870
           LSGKEAKGPLQDGATTDANGRANAVASSTERTPGS
Sbjct: 960 LSGKEAKGPLQDGATTDANGRANAVASSTERTPGS 994


>gi|7662284 microtubule associated monoxygenase, calponin and LIM
           domain containing 2 [Homo sapiens]
          Length = 1124

 Score =  997 bits (2578), Expect = 0.0
 Identities = 511/744 (68%), Positives = 602/744 (80%), Gaps = 11/744 (1%)

Query: 1   MEERKHETMNPAHVLFDRFVQATTCKGTLKAFQELCDHLELKPKDYRSFYHKLKSKLNYW 60
           M E + E    A  +F+ FVQA+TCKGTL+AF  L  HL+L P D+R+FY KLKSK+  W
Sbjct: 1   MGENEDEKQAQAGQVFENFVQASTCKGTLQAFNILTRHLDLDPLDHRNFYSKLKSKVTTW 60

Query: 61  KAKALWAKLDKRGSHKDYKKGKACTNTKCLIIGAGPCGLRTAIDLSLLGAKVVVIEKRDA 120
           KAKALW KLDKRGSHK+YK+GK+CTNTKCLI+G GPCGLRTAI+L+ LGAKVVV+EKRD+
Sbjct: 61  KAKALWYKLDKRGSHKEYKRGKSCTNTKCLIVGGGPCGLRTAIELAYLGAKVVVVEKRDS 120

Query: 121 FSRNNVLHLWPFTIHDLRGLGAKKFYGKFCAGAIDHISIRQLQLILLKVALILGIEIHVN 180
           FSRNNVLHLWPFTIHDLRGLGAKKFYGKFCAG+IDHISIRQLQLIL KVAL+LG+EIHVN
Sbjct: 121 FSRNNVLHLWPFTIHDLRGLGAKKFYGKFCAGSIDHISIRQLQLILFKVALMLGVEIHVN 180

Query: 181 VEFQGLIQPPEDQENERIGWRALVHPKTHPVSEYEFEVIIGGDGRRNTLEGFRRKEFRGK 240
           VEF  +++PPEDQEN++IGWRA   P  H +SE+EF+VIIG DGRRNTLEGFRRKEFRGK
Sbjct: 181 VEFVKVLEPPEDQENQKIGWRAEFLPTDHSLSEFEFDVIIGADGRRNTLEGFRRKEFRGK 240

Query: 241 LAIAITANFINRNTTAEAKVEEISGVAFIFNQKFFQELREATGIDLENIVYYKDDTHYFV 300
           LAIAITANFINRN+TAEAKVEEISGVAFIFNQKFFQ+L+E TGIDLENIVYYKD THYFV
Sbjct: 241 LAIAITANFINRNSTAEAKVEEISGVAFIFNQKFFQDLKEETGIDLENIVYYKDCTHYFV 300

Query: 301 MTAKKQSLLDKGVILHDYADTELLLSRENVDQEALLSYAREAADFSTQQQLPSLDFAINH 360
           MTAKKQSLLDKGVI++DY DTE+LL  ENV+Q+ LLSYAREAADF+T  QLPSLDFA+NH
Sbjct: 301 MTAKKQSLLDKGVIINDYIDTEMLLCAENVNQDNLLSYAREAADFATNYQLPSLDFAMNH 360

Query: 361 YGQPDVAMFDFTCMYASENAALVREQNGHQLLVALVGDSLLEPFWPMGTGIARGFLAAMD 420
           YGQPDVAMFDFTCMYASENAALVRE+  HQLLVALVGDSLLEPFWPMGTG ARGFLAA D
Sbjct: 361 YGQPDVAMFDFTCMYASENAALVRERQAHQLLVALVGDSLLEPFWPMGTGCARGFLAAFD 420

Query: 421 SAWMVRSWSLGTSPLEVLAERESIYRLLPQTTPENVSKNFSQYSIDPVTRYPNINVNFLR 480
           +AWMV+SW+ GT PLE+LAERES+YRLLPQTTPEN++KNF QY++DP TRYPN+N + +R
Sbjct: 421 TAWMVKSWNQGTPPLELLAERESLYRLLPQTTPENINKNFEQYTLDPGTRYPNLNSHCVR 480

Query: 481 PSQVRHLYDTGETKDIHLEMESLVNSRTTPKLTRNESVARSSKLLGWCQRQTDGYAGVNV 540
           P QV+HLY T E +  H  +E L + R +  L+R ES  R SKLL WCQ+QT+GY  VNV
Sbjct: 481 PHQVKHLYITKELE--HYPLERLGSVRRSVNLSRKESDIRPSKLLTWCQQQTEGYQHVNV 538

Query: 541 TDLTMSWKSGLALCAIIHRYRPDLIDFDSLDEQNVEKNNQLAFDIAEKELGISPIMTGKE 600
           TDLT SW+SGLALCAIIHR+RP+LI+FDSL+E +  +NNQLAFD+AE+E GI P+ TGKE
Sbjct: 539 TDLTTSWRSGLALCAIIHRFRPELINFDSLNEDDAVENNQLAFDVAEREFGIPPVTTGKE 598

Query: 601 MASVGEPDKLSMVMYLTQFYEMFKDS-LPSSDTLDLNAEEKAVLIASTRSPISFLSKLGQ 659
           MAS  EPDKLSMVMYL++FYE+F+ + L   D+   N  E A L +  +S IS  + L  
Sbjct: 599 MASAQEPDKLSMVMYLSKFYELFRGTPLRPVDSWRKNYGENADL-SLAKSSIS-NNYLNL 656

Query: 660 TISRKRSPK-DKKEKDLDGAGKRRKTSQSEEEEAPRGHRGERPTLVSTLTDRRMDVAVGN 718
           T  RKR+P+ D +  + D   +RRK   + +E +    R      + +  +       GN
Sbjct: 657 TFPRKRTPRVDGQTGENDMNKRRRKGFTNLDEPSNFSSRS-----LGSNQECGSSKEGGN 711

Query: 719 QNKVKYMATQLLAKFEENAPAQSI 742
           QNKVK MA QLLAKFEE+    S+
Sbjct: 712 QNKVKSMANQLLAKFEESTRNPSL 735



 Score =  137 bits (346), Expect = 8e-32
 Identities = 85/209 (40%), Positives = 113/209 (54%), Gaps = 17/209 (8%)

Query: 636  NAEEKAVLIASTRS----PISFLSKLGQTISRKRSPKDKKEKDLDGAGKRRKTSQS---- 687
            N +EKA  +AS       P + L   G + +   SP  +       A     T  S    
Sbjct: 867  NIKEKAAHLASMFGHGDFPQNKLLSKGLSHTHPPSPPSRLPSPDPAASSSPSTVDSASPA 926

Query: 688  -EEEEAPRG---HRGERPTLVSTLTDRRMDVAVGNQNKVKYMATQLLAKFEENAPAQSIG 743
             +E+++P G   H     T+   LT  ++   +G   +V  +    +      A A S  
Sbjct: 927  RKEKKSPSGFHFHPSHLRTVHPQLTVGKVSSGIGAAAEV--LVNLYMNDHRPKAQATSPD 984

Query: 744  IRRQGSMKKEFPQNLGGSDTCYFCQKRVYVMERLSAEGKFFHRSCFKCEYCATTLRLSAY 803
            +    SM+K FP NLGGSDTCYFC+KRVYVMERLSAEG FFHR CF+C  CATTLRL+AY
Sbjct: 985  LE---SMRKSFPLNLGGSDTCYFCKKRVYVMERLSAEGHFFHRECFRCSICATTLRLAAY 1041

Query: 804  AYDIEDGKFYCKPHYCYRLSGYAQRKRPA 832
             +D ++GKFYCKPH+ +  +   QRKR A
Sbjct: 1042 TFDCDEGKFYCKPHFIHCKTNSKQRKRRA 1070


>gi|205360947 microtubule associated monoxygenase, calponin and LIM
           domain containing 1 isoform 1 [Homo sapiens]
          Length = 1067

 Score =  730 bits (1885), Expect = 0.0
 Identities = 419/954 (43%), Positives = 550/954 (57%), Gaps = 92/954 (9%)

Query: 10  NPAHVLFDRFVQATTCKGTLKAFQELCDHLELKPKDYRSFYHKLKSKLNYWKAKALWAKL 69
           NPAH  F+ F+QA  C+  L +FQELC  L L+P      YHK+K +LNYW AK+LW KL
Sbjct: 8   NPAHAHFESFLQAQLCQDVLSSFQELCGALGLEPGGGLPQYHKIKDQLNYWSAKSLWTKL 67

Query: 70  DKRGSHKDYKKGKACTNTKCLIIGAGPCGLRTAIDLSLLGAKVVVIEKRDAFSRNNVLHL 129
           DKR     Y++G+ACT+TKCL++GAGPCGLR A++L+LLGA+VV++EKR  FSR+NVLHL
Sbjct: 68  DKRAGQPVYQQGRACTSTKCLVVGAGPCGLRVAVELALLGARVVLVEKRTKFSRHNVLHL 127

Query: 130 WPFTIHDLRGLGAKKFYGKFCAGAIDHISIRQLQLILLKVALILGIEIHVNVEFQGLIQP 189
           WPFTIHDLR LGAKKFYG+FC G +DHISIRQLQL+LLKVAL+LG+EIH  V F GL  P
Sbjct: 128 WPFTIHDLRALGAKKFYGRFCTGTLDHISIRQLQLLLLKVALLLGVEIHWGVTFTGLQPP 187

Query: 190 PEDQENERIGWRALVHPKTHP-VSEYEFEVIIGGDGRRNTLEGFRRKEFRGKLAIAITAN 248
           P        GWRA + P     ++ YEF+V+I   G +   EGF+ +E RGKLAI ITAN
Sbjct: 188 PRKGS----GWRAQLQPNPPAQLANYEFDVLISAAGGKFVPEGFKVREMRGKLAIGITAN 243

Query: 249 FINRNTTAEAKVEEISGVAFIFNQKFFQELREATGIDLENIVYYKDDTHYFVMTAKKQSL 308
           F+N  T  E +V EISGVA I+NQ FFQ L +ATGIDLENIVYYKDDTHYFVMTAKKQ L
Sbjct: 244 FVNGRTVEETQVPEISGVARIYNQSFFQSLLKATGIDLENIVYYKDDTHYFVMTAKKQCL 303

Query: 309 LDKGVILHDYADTELLLSRENVDQEALLSYAREAADFSTQQQLPSLDFAINHYGQPDVAM 368
           L  GV+  D+ DT  LL   NV  EAL  + R AADF+T  +L  L+FA + +GQPDV+ 
Sbjct: 304 LRLGVLRQDWPDTNRLLGSANVVPEALQRFTRAAADFATHGKLGKLEFAQDAHGQPDVSA 363

Query: 369 FDFTCMYASENAALVREQNGHQLLVALVGDSLLEPFWPMGTGIARGFLAAMDSAWMVRSW 428
           FDFT M  +E++A V+E++G +LL+ LVGD L+EPFWP+GTG+ARGFLAA D+AWMV+ W
Sbjct: 364 FDFTSMMRAESSARVQEKHGARLLLGLVGDCLVEPFWPLGTGVARGFLAAFDAAWMVKRW 423

Query: 429 SLGTSPLEVLAERESIYRLLPQTTPENVSKNFSQYSIDPVTRYPNINVNFLRPSQVRHLY 488
           + G   LEVLAERES+Y+LL QT+PEN+ +N +QY +DP TRYPN+N+  + P+QVR LY
Sbjct: 424 AEGAESLEVLAERESLYQLLSQTSPENMHRNVAQYGLDPATRYPNLNLRAVTPNQVRDLY 483

Query: 489 DTGETKDIHLEMESLVNSRTTPKLTRNESVARSSKLLGWCQRQTDGYAGVNVTDLTMSWK 548
           D    + +        N +T   +    S     +LL WCQ QT GY GV+V+DL+ SW 
Sbjct: 484 DVLAKEPVQRN-----NDKTDTGMPATGSAGTQEELLRWCQEQTAGYPGVHVSDLSSSWA 538

Query: 549 SGLALCAIIHRYRPDLIDFDSLDEQNVEKNNQLAFDIAEKELGISPIMTGKEMASVGEPD 608
            GLALCA+++R +P L++   L      +    A  +AE ELGI+P+++ +  A V   D
Sbjct: 539 DGLALCALVYRLQPGLLEPSELQGLGALEATAWALKVAENELGITPVVSAQ--AVVAGSD 596

Query: 609 KLSMVMYLTQFYEMFKDSLPSSDTLDLNAEEKAVLIASTRSPISFLSKLGQTISRKRSPK 668
            L ++ YL+ F+  FK    S   +   +         T S + FLSKL +T+ R R+  
Sbjct: 597 PLGLIAYLSHFHSAFKSMAHSPGPVSQAS-------PGTSSAVLFLSKLQRTLQRSRA-- 647

Query: 669 DKKEKDLDGAGKRRKTSQSEEEEAPRGHRGERPTLVSTLTDRRMDVAVGNQNKVKYMATQ 728
             KE   D  GK+ +     E  +        P +  T                      
Sbjct: 648 --KENAEDAGGKKLRLEMEAETPSTEVPPDPEPGVPLT---------------------- 683

Query: 729 LLAKFEENAPAQSIGIRRQGSMKKEFPQNLGGSDTCYFCQKRVYVMERLSAEGKFFHRSC 788
                    P+Q               Q  G  D C  C + +YV+ERL   G FFHRSC
Sbjct: 684 --------PPSQH--------------QEAGAGDLCALCGEHLYVLERLCVNGHFFHRSC 721

Query: 789 FKCEYCATTLRLSAYAYDIEDGKFYCKPHYCYRLSGYAQRKRPAVAPLSGKEAKGPLQDG 848
           F+C  C  TL    Y     DG FYC  H         Q    A     G E+     + 
Sbjct: 722 FRCHTCEATLWPGGYEQHPGDGHFYCLQH-------LPQTDHKAEGSDRGPES----PEL 770

Query: 849 ATTDANGRANAVASSTERTPGSG-VNGLEEPSIAKRLRGTPERIELENYRLSLRQAEALQ 907
            T   N     +++ T    G+G V    +P+  +    +PER  L +  L+L     ++
Sbjct: 771 PTPSENSMPPGLSTPTASQEGAGPVPDPSQPTRRQIRLSSPERQRLSS--LNLTPDPEME 828

Query: 908 EVPEETQ-----AEHNL-SSVLDTG-----AEEDVASSSSESEMEEEGEEEEEE 950
             P+  +     A H L SS +  G      +  VA    E E     EEEEE+
Sbjct: 829 PPPKPPRSCSALARHALESSFVGWGLPVQSPQALVAMEKEEKESPFSSEEEEED 882



 Score =  125 bits (314), Expect = 4e-28
 Identities = 104/346 (30%), Positives = 166/346 (47%), Gaps = 49/346 (14%)

Query: 1640 SQGKERRPDSPTRPT-LRGSEEPTLKHEATSEEVLSPPSDSGGPDGSFTSSEGSSGKSKK 1698
            ++G +R P+SP  PT    S  P L     S+E   P  D   P             +++
Sbjct: 758  AEGSDRGPESPELPTPSENSMPPGLSTPTASQEGAGPVPDPSQP-------------TRR 804

Query: 1699 RSSLFSPRRNKKEKKS---KGEGRPPEKPSSNLLEEAAAKPKSLWKSVFSGYKKDKKKKA 1755
            +  L SP R +    +     E  PP KP  +     +A  +   +S F G+        
Sbjct: 805  QIRLSSPERQRLSSLNLTPDPEMEPPPKPPRS----CSALARHALESSFVGW-------- 852

Query: 1756 DDKSCPSTPSSGATVDSGKHRVLPVVRAELQLRRQLSFSEDSDLSSDDVLEKSSQKSRRE 1815
                       G  V S +   L  +  E +     S  E+ D+  D  +E++ Q   + 
Sbjct: 853  -----------GLPVQSPQ--ALVAMEKEEKESPFSSEEEEEDVPLDSDVEQALQTFAK- 898

Query: 1816 PRTYTEEELNAKLTRRVQKAARRQAKQEELKRLHRAQIIQRQLQQVEERQRRLEERGVAV 1875
                T   +N   T R  +   R+AK+EE+KR  +AQ IQR+L ++E   R LE  GV +
Sbjct: 899  ----TSGTMNNYPTWR--RTLLRRAKEEEMKRFCKAQTIQRRLNEIEAALRELEAEGVKL 952

Query: 1876 EKALRGEAGMGKKDDPKLMQEWFKLVQEKNAMVRYESELMIFARELELEDRQSRLQQELR 1935
            E ALR ++   ++     + +  +LV +KN++V  E+ELMI  +EL LE++Q +L QELR
Sbjct: 953  ELALRRQSSSPEQQKKLWVGQLLQLVDKKNSLVAEEAELMITVQELNLEEKQWQLDQELR 1012

Query: 1936 ERMAVEDHLKTEEELSEEKQILNEMLEVVEQRDSLVALLEEQRLRE 1981
              M  E++LKT  +   E Q+L +++++V QRD+L+   EE+RL E
Sbjct: 1013 GYMNREENLKTAADRQAEDQVLRKLVDLVNQRDALIRFQEERRLSE 1058



 Score = 39.7 bits (91), Expect = 0.030
 Identities = 41/183 (22%), Positives = 63/183 (34%), Gaps = 32/183 (17%)

Query: 1364 KSYSVEKSPQDEGLHLLKPLSIPKRLGLPKPEGEPLS-LPTPRSPSDRELRSAQEERREL 1422
            K+   ++ P+   L      S+P  L  P    E    +P P  P+ R++R +  ER+ L
Sbjct: 757  KAEGSDRGPESPELPTPSENSMPPGLSTPTASQEGAGPVPDPSQPTRRQIRLSSPERQRL 816

Query: 1423 SSSSGLGLHGSSSNMKTLGSQSFNTSDSAMLTPPSSPPPPPPPGEEPATLRRKLREAEPN 1482
            SS +                          LTP     PPP P    + L R   E+   
Sbjct: 817  SSLN--------------------------LTPDPEMEPPPKPPRSCSALARHALESSFV 850

Query: 1483 ASVVPPPLPATWMRPPREPAQPPREEVRKSFVESVEEIPFADDVEDTYDDKTEDSSLQEK 1542
               +P   P   +   +E  + P      S  E  E++P   DVE       + S     
Sbjct: 851  GWGLPVQSPQALVAMEKEEKESP-----FSSEEEEEDVPLDSDVEQALQTFAKTSGTMNN 905

Query: 1543 FFT 1545
            + T
Sbjct: 906  YPT 908


>gi|226530313 microtubule associated monoxygenase, calponin and LIM
           domain containing 1 isoform 2 [Homo sapiens]
          Length = 981

 Score =  388 bits (996), Expect = e-107
 Identities = 191/306 (62%), Positives = 231/306 (75%), Gaps = 5/306 (1%)

Query: 10  NPAHVLFDRFVQATTCKGTLKAFQELCDHLELKPKDYRSFYHKLKSKLNYWKAKALWAKL 69
           NPAH  F+ F+QA  C+  L +FQELC  L L+P      YHK+K +LNYW AK+LW KL
Sbjct: 8   NPAHAHFESFLQAQLCQDVLSSFQELCGALGLEPGGGLPQYHKIKDQLNYWSAKSLWTKL 67

Query: 70  DKRGSHKDYKKGKACTNTKCLIIGAGPCGLRTAIDLSLLGAKVVVIEKRDAFSRNNVLHL 129
           DKR     Y++G+ACT+TKCL++GAGPCGLR A++L+LLGA+VV++EKR  FSR+NVLHL
Sbjct: 68  DKRAGQPVYQQGRACTSTKCLVVGAGPCGLRVAVELALLGARVVLVEKRTKFSRHNVLHL 127

Query: 130 WPFTIHDLRGLGAKKFYGKFCAGAIDHISIRQLQLILLKVALILGIEIHVNVEFQGLIQP 189
           WPFTIHDLR LGAKKFYG+FC G +DHISIRQLQL+LLKVAL+LG+EIH  V F GL  P
Sbjct: 128 WPFTIHDLRALGAKKFYGRFCTGTLDHISIRQLQLLLLKVALLLGVEIHWGVTFTGLQPP 187

Query: 190 PEDQENERIGWRALVHPK-THPVSEYEFEVIIGGDGRRNTLEGFRRKEFRGKLAIAITAN 248
           P     +  GWRA + P     ++ YEF+V+I   G +   EGF+ +E RGKLAI ITAN
Sbjct: 188 P----RKGSGWRAQLQPNPPAQLANYEFDVLISAAGGKFVPEGFKVREMRGKLAIGITAN 243

Query: 249 FINRNTTAEAKVEEISGVAFIFNQKFFQELREATGIDLENIVYYKDDTHYFVMTAKKQSL 308
           F+N  T  E +V EISGVA I+NQ FFQ L +ATGIDLENIVYYKDDTHYFVMTAKKQ L
Sbjct: 244 FVNGRTVEETQVPEISGVARIYNQSFFQSLLKATGIDLENIVYYKDDTHYFVMTAKKQCL 303

Query: 309 LDKGVI 314
           L  GV+
Sbjct: 304 LRLGVL 309



 Score =  270 bits (691), Expect = 8e-72
 Identities = 186/563 (33%), Positives = 262/563 (46%), Gaps = 87/563 (15%)

Query: 400 LLEPFWPMGTGIARGFLAAMDSAWMVRSWSLGTSPLEVLAERESIYRLLPQTTPENVSKN 459
           L +PFWP+GTG+ARGFLAA D+AWMV+ W+ G   LEVLAERES+Y+LL QT+PEN+ +N
Sbjct: 309 LRQPFWPLGTGVARGFLAAFDAAWMVKRWAEGAESLEVLAERESLYQLLSQTSPENMHRN 368

Query: 460 FSQYSIDPVTRYPNINVNFLRPSQVRHLYDTGETKDIHLEMESLVNSRTTPKLTRNESVA 519
            +QY +DP TRYPN+N+  + P+QVR LYD    + +        N +T   +    S  
Sbjct: 369 VAQYGLDPATRYPNLNLRAVTPNQVRDLYDVLAKEPVQRN-----NDKTDTGMPATGSAG 423

Query: 520 RSSKLLGWCQRQTDGYAGVNVTDLTMSWKSGLALCAIIHRYRPDLIDFDSLDEQNVEKNN 579
              +LL WCQ QT GY GV+V+DL+ SW  GLALCA+++R +P L++   L      +  
Sbjct: 424 TQEELLRWCQEQTAGYPGVHVSDLSSSWADGLALCALVYRLQPGLLEPSELQGLGALEAT 483

Query: 580 QLAFDIAEKELGISPIMTGKEMASVGEPDKLSMVMYLTQFYEMFKDSLPSSDTLDLNAEE 639
             A  +AE ELGI+P+++ +  A V   D L ++ YL+ F+  FK    S   +   +  
Sbjct: 484 AWALKVAENELGITPVVSAQ--AVVAGSDPLGLIAYLSHFHSAFKSMAHSPGPVSQAS-- 539

Query: 640 KAVLIASTRSPISFLSKLGQTISRKRSPKDKKEKDLDGAGKRRKTSQSEEEEAPRGHRGE 699
                  T S + FLSKL +T+ R R+    KE   D  GK+ +     E  +       
Sbjct: 540 -----PGTSSAVLFLSKLQRTLQRSRA----KENAEDAGGKKLRLEMEAETPSTEVPPDP 590

Query: 700 RPTLVSTLTDRRMDVAVGNQNKVKYMATQLLAKFEENAPAQSIGIRRQGSMKKEFPQNLG 759
            P +  T                               P+Q               Q  G
Sbjct: 591 EPGVPLT------------------------------PPSQH--------------QEAG 606

Query: 760 GSDTCYFCQKRVYVMERLSAEGKFFHRSCFKCEYCATTLRLSAYAYDIEDGKFYCKPHYC 819
             D C  C + +YV+ERL   G FFHRSCF+C  C  TL    Y     DG FYC  H  
Sbjct: 607 AGDLCALCGEHLYVLERLCVNGHFFHRSCFRCHTCEATLWPGGYEQHPGDGHFYCLQH-- 664

Query: 820 YRLSGYAQRKRPAVAPLSGKEAKGPLQDGATTDANGRANAVASSTERTPGSG-VNGLEEP 878
                  Q    A     G E+     +  T   N     +++ T    G+G V    +P
Sbjct: 665 -----LPQTDHKAEGSDRGPES----PELPTPSENSMPPGLSTPTASQEGAGPVPDPSQP 715

Query: 879 SIAKRLRGTPERIELENYRLSLRQAEALQEVPEETQ-----AEHNL-SSVLDTG-----A 927
           +  +    +PER  L +  L+L     ++  P+  +     A H L SS +  G      
Sbjct: 716 TRRQIRLSSPERQRLSS--LNLTPDPEMEPPPKPPRSCSALARHALESSFVGWGLPVQSP 773

Query: 928 EEDVASSSSESEMEEEGEEEEEE 950
           +  VA    E E     EEEEE+
Sbjct: 774 QALVAMEKEEKESPFSSEEEEED 796



 Score =  125 bits (314), Expect = 4e-28
 Identities = 104/346 (30%), Positives = 166/346 (47%), Gaps = 49/346 (14%)

Query: 1640 SQGKERRPDSPTRPT-LRGSEEPTLKHEATSEEVLSPPSDSGGPDGSFTSSEGSSGKSKK 1698
            ++G +R P+SP  PT    S  P L     S+E   P  D   P             +++
Sbjct: 672  AEGSDRGPESPELPTPSENSMPPGLSTPTASQEGAGPVPDPSQP-------------TRR 718

Query: 1699 RSSLFSPRRNKKEKKS---KGEGRPPEKPSSNLLEEAAAKPKSLWKSVFSGYKKDKKKKA 1755
            +  L SP R +    +     E  PP KP  +     +A  +   +S F G+        
Sbjct: 719  QIRLSSPERQRLSSLNLTPDPEMEPPPKPPRS----CSALARHALESSFVGW-------- 766

Query: 1756 DDKSCPSTPSSGATVDSGKHRVLPVVRAELQLRRQLSFSEDSDLSSDDVLEKSSQKSRRE 1815
                       G  V S +   L  +  E +     S  E+ D+  D  +E++ Q   + 
Sbjct: 767  -----------GLPVQSPQ--ALVAMEKEEKESPFSSEEEEEDVPLDSDVEQALQTFAK- 812

Query: 1816 PRTYTEEELNAKLTRRVQKAARRQAKQEELKRLHRAQIIQRQLQQVEERQRRLEERGVAV 1875
                T   +N   T R  +   R+AK+EE+KR  +AQ IQR+L ++E   R LE  GV +
Sbjct: 813  ----TSGTMNNYPTWR--RTLLRRAKEEEMKRFCKAQTIQRRLNEIEAALRELEAEGVKL 866

Query: 1876 EKALRGEAGMGKKDDPKLMQEWFKLVQEKNAMVRYESELMIFARELELEDRQSRLQQELR 1935
            E ALR ++   ++     + +  +LV +KN++V  E+ELMI  +EL LE++Q +L QELR
Sbjct: 867  ELALRRQSSSPEQQKKLWVGQLLQLVDKKNSLVAEEAELMITVQELNLEEKQWQLDQELR 926

Query: 1936 ERMAVEDHLKTEEELSEEKQILNEMLEVVEQRDSLVALLEEQRLRE 1981
              M  E++LKT  +   E Q+L +++++V QRD+L+   EE+RL E
Sbjct: 927  GYMNREENLKTAADRQAEDQVLRKLVDLVNQRDALIRFQEERRLSE 972



 Score = 39.7 bits (91), Expect = 0.030
 Identities = 41/183 (22%), Positives = 63/183 (34%), Gaps = 32/183 (17%)

Query: 1364 KSYSVEKSPQDEGLHLLKPLSIPKRLGLPKPEGEPLS-LPTPRSPSDRELRSAQEERREL 1422
            K+   ++ P+   L      S+P  L  P    E    +P P  P+ R++R +  ER+ L
Sbjct: 671  KAEGSDRGPESPELPTPSENSMPPGLSTPTASQEGAGPVPDPSQPTRRQIRLSSPERQRL 730

Query: 1423 SSSSGLGLHGSSSNMKTLGSQSFNTSDSAMLTPPSSPPPPPPPGEEPATLRRKLREAEPN 1482
            SS +                          LTP     PPP P    + L R   E+   
Sbjct: 731  SSLN--------------------------LTPDPEMEPPPKPPRSCSALARHALESSFV 764

Query: 1483 ASVVPPPLPATWMRPPREPAQPPREEVRKSFVESVEEIPFADDVEDTYDDKTEDSSLQEK 1542
               +P   P   +   +E  + P      S  E  E++P   DVE       + S     
Sbjct: 765  GWGLPVQSPQALVAMEKEEKESP-----FSSEEEEEDVPLDSDVEQALQTFAKTSGTMNN 819

Query: 1543 FFT 1545
            + T
Sbjct: 820  YPT 822


>gi|118918413 MICAL C-terminal like [Homo sapiens]
          Length = 695

 Score =  205 bits (522), Expect = 3e-52
 Identities = 162/479 (33%), Positives = 244/479 (50%), Gaps = 50/479 (10%)

Query: 1540 QEKFFTPPSCWPRPEKPRHPPLAKENGRLPA------LEGTLQPQKRGLPL-VSAEAKEL 1592
            QEK  TP     + +  R+ P  K   RL A      LE  L   + G       E+K L
Sbjct: 247  QEKMGTPAE---QAQGERNVPPPKSPLRLIANAIRRSLEPLLSNSEGGKKAWAKQESKTL 303

Query: 1593 AEERMRAREKSVKSQALRDAMARQLSRMQQMELASGAPRPRKASSAPSQGKERRPDSPTR 1652
              +         K+ + +D       R Q    +   P  R   S P++  +  P   + 
Sbjct: 304  PAQACTRSFSLRKTNSNKDGDQHSPGRNQSSAFSPPDPALR-THSLPNRPSKVFPALRSP 362

Query: 1653 PTLRGSEEPTLKHEATSEEVLSPPSDSGGPDGSFTSSEGSSGKSKKRSSLFSPRRNK--- 1709
            P  +  + PTL  + + +E          PD        +S   KKR SLFS  R K   
Sbjct: 363  PCSKIEDVPTLLEKVSLQENF--------PD--------ASKPPKKRISLFSSLRLKDKS 406

Query: 1710 -----KEKKSKGEGRPP-EKPSSNLLEEAAAKPKSLWKSVFSGYKKDKKKKA--DDKSCP 1761
                 +E + + + R     P   +L E +A+     + +   +K    ++A       P
Sbjct: 407  FESFLQESRQRKDIRDLFGSPKRKVLPEDSAQAL---EKLLQPFKSTSLRQAAPPPPPPP 463

Query: 1762 STPSSGATVDSGKHRVLPVVRAELQLRRQLSFSEDSDLSSDDVLEKSSQKSRREPRTYTE 1821
              P    T      +  P+ RA++      S S  S  S+D+  +       +E +T   
Sbjct: 464  PPPPPPPTAGGADSKNFPL-RAQVT-EASSSASSTSSSSADEEFDPQLSLQLKEKKTLRR 521

Query: 1822 EELNAKLTRRVQKAARRQAKQEELKRLHRAQIIQRQLQQVEERQRRLEERGVAVEKALRG 1881
                    ++++KA ++  KQEELKRL++AQ IQRQL++VEERQR  E +GV +EKALRG
Sbjct: 522  R-------KKLEKAMKQLVKQEELKRLYKAQAIQRQLEEVEERQRASEIQGVRLEKALRG 574

Query: 1882 EAGMGKKDDPKLMQEWFKLVQEKNAMVRYESELMIFARELELEDRQSRLQQELRERMAVE 1941
            EA  G +D+ +L+QEWFKLV EKN ++RYESEL+I A+ELELED QSRL+Q+LRE+M  E
Sbjct: 575  EADSGTQDEAQLLQEWFKLVLEKNKLMRYESELLIMAQELELEDHQSRLEQKLREKMLKE 634

Query: 1942 DHLKTEEELSEEKQILNEMLEVVEQRDSLVALLEEQRLREREEDKDLEAAMLSKGFSLN 2000
            +  K E++L+EE+++  E+++V+EQRD LV  LEEQR+RE+ ED+  E+ + S+G  L+
Sbjct: 635  ESQKDEKDLNEEQEVFTELMQVIEQRDKLVDSLEEQRIREKAEDQHFESFVFSRGCQLS 693



 Score = 37.4 bits (85), Expect = 0.15
 Identities = 58/242 (23%), Positives = 89/242 (36%), Gaps = 25/242 (10%)

Query: 1265 QPSTEATVPSPTQSPIRFQPAPAKTSTPLAPLPVQSQSDTKD--RLGSPLAVDEALRRSD 1322
            Q   E  VP P +SP+R      + S  L PL   S+   K   +  S     +A  RS 
Sbjct: 256  QAQGERNVPPP-KSPLRLIANAIRRS--LEPLLSNSEGGKKAWAKQESKTLPAQACTRSF 312

Query: 1323 LVEEFWMKSAEIRRSLGLTPVDRSKGPEPSFPTPAFRPVSLKSYSVEKSPQDEGLH---- 1378
             + +        + S G         P+P+  T +      K +   +SP    +     
Sbjct: 313  SLRKTNSNKDGDQHSPGRNQSSAFSPPDPALRTHSLPNRPSKVFPALRSPPCSKIEDVPT 372

Query: 1379 LLKPLSIPKRL-GLPKPEGEPLSLPTPRSPSDRELRSAQEERRE-------LSSSSGLGL 1430
            LL+ +S+ +      KP  + +SL +     D+   S  +E R+         S     L
Sbjct: 373  LLEKVSLQENFPDASKPPKKRISLFSSLRLKDKSFESFLQESRQRKDIRDLFGSPKRKVL 432

Query: 1431 HGSSSNMKTLGSQSFNTSDSAMLTPPSSPPPPPPPGEEPA--------TLRRKLREAEPN 1482
               S+       Q F ++      PP  PPPPPPP    A         LR ++ EA  +
Sbjct: 433  PEDSAQALEKLLQPFKSTSLRQAAPPPPPPPPPPPPPPTAGGADSKNFPLRAQVTEASSS 492

Query: 1483 AS 1484
            AS
Sbjct: 493  AS 494


>gi|33667117 MICAL-like 2 isoform 1 [Homo sapiens]
          Length = 904

 Score =  147 bits (372), Expect = 8e-35
 Identities = 91/294 (30%), Positives = 144/294 (48%), Gaps = 65/294 (22%)

Query: 527 WCQRQTDGYAGVNVTDLTMSWKSGLALCAIIHRYRPDLIDFDSLDEQNVEKNNQLAFDIA 586
           WC++Q +GY  VN+ ++T S++ GLA CAI+HR+RPDLI+F +L ++N+ +NN+LAF +A
Sbjct: 10  WCRQQCEGYRDVNICNMTTSFRDGLAFCAILHRHRPDLINFSALKKENIYENNKLAFRVA 69

Query: 587 EKELGISPIMTGKEMASVGEPDKLSMVMYLTQFYEMFKDSLPSSDTLDLNAEEKAVLIAS 646
           E+ LGI  ++  ++M ++  PD+LS++ Y++Q+Y  F                       
Sbjct: 70  EEHLGIPALLDAEDMVALKVPDRLSILTYVSQYYNYFHG--------------------- 108

Query: 647 TRSPISFLSKLGQTISRKRSPKDKKEKDLDGAGKRRKTSQSEEEEAPRGHRGERPTLVST 706
            RSPI  +                       AG +R +  SEEE + +    +   L S 
Sbjct: 109 -RSPIGGM-----------------------AGVKRASEDSEEEPSGKKAPVQAAKLPSP 144

Query: 707 LTDRRMDVAVGNQNKVKYMATQLLAKFEENAPAQSIGIRRQGSMKKEFPQNLGG---SDT 763
              R+  ++    N V       + +  E A          G    +  Q L G   S T
Sbjct: 145 APARKPPLSPAQTNPV-------VQRRNEGA----------GGPPPKTDQALAGSLVSST 187

Query: 764 CYFCQKRVYVMERLSAEGKFFHRSCFKCEYCATTLRLSAYAYDIEDGKFYCKPH 817
           C  C K V++++R  A+G+ +HRSCF+C+ C+ TL   AY    E G F C  H
Sbjct: 188 CGVCGKHVHLVQRHLADGRLYHRSCFRCKQCSCTLHSGAYKATGEPGTFVCTSH 241



 Score =  108 bits (271), Expect = 4e-23
 Identities = 152/578 (26%), Positives = 235/578 (40%), Gaps = 70/578 (12%)

Query: 1435 SNMKTLGSQSFNTSDSAMLTPPSSPPPPPPPGEEPATLRR--KLREAEPNASVVPPPLPA 1492
            +N   +G  S     +A  + P+ PP  P P   PAT +     R A P  ++      A
Sbjct: 341  TNSSPMGWSSAAPCTAAAASHPAVPPSAPDP--RPATPQGGGAPRVAAPQTTLSSSSTSA 398

Query: 1493 TWMRPPR-EPAQPPREEVRKSFVESVEEIPFADDVEDTYDDKTEDSSLQEKFFTPPSCWP 1551
              + PP   P+    ++ R  F ++    P               +SL  +        P
Sbjct: 399  ATVDPPAWTPSASRTQQARNKFFQTSAVPP--------------GTSLSGR-------GP 437

Query: 1552 RPEKPRHPPLAKENGR------LPALEGTLQPQKRGLPLVSAEAKELAEERMRAREKSVK 1605
             P        +KE  R      L ALE    P   G P  +  A   ++ +  A + S  
Sbjct: 438  TPSLVLSKDSSKEQARNFLKQALSALEEAGAPAP-GRPSPATAAVPSSQPKTEAPQASPL 496

Query: 1606 SQALRDAMARQLSRMQQMELAS--GAPRPRKASSAPSQGKERRPDSPTRPTLRGSEEPTL 1663
            ++ L+ +  R L    +ME  +        +AS+ P  G+    +S     +     P  
Sbjct: 497  AKPLQSSSPRVLGLPSRMEPPAPLSTSSTSQASALPPAGRRNLAESSGVGRVGAGSRP-- 554

Query: 1664 KHEATSEEVLSPPSDSGGPDGSFTSSEGSS-GKSKKRSSLFS-PRRNKKEKKSKGEGRPP 1721
            K EA    +    S +   D S +  EG   G +  R++L    RR+  E+  K     P
Sbjct: 555  KPEAP---MAKGKSTTLTQDMSTSLQEGQEDGPAGWRANLKPVDRRSPAERTLK-----P 606

Query: 1722 EKPSSNLLEEAAAKPKSLWKSVFSGYKKDKKKKADDKSCPSTPSSGATVDSGKHRVLPVV 1781
            ++P +     A   P+ +  S F+G              P   S G +        LP  
Sbjct: 607  KEPRALAEPRAGEAPRKVSGS-FAGSVHITLTPVRPDRTPRPASPGPS--------LPAR 657

Query: 1782 RAELQLRRQLSFSEDSDLSSDDVLEKSSQKSRREPRTYTEEE----LNAKLTRRVQKAAR 1837
                  RR+L+     D+  D+ L           +++ EEE    L  K  R +  A  
Sbjct: 658  SPSPPRRRRLAVPASLDVC-DNWLRPEPPGQEARVQSWKEEEKKPHLQGKPGRPLSPANV 716

Query: 1838 RQAKQEELK---RLHRAQI----IQRQLQQVEERQRRLEERGVAVEKALRGEAGMGKKDD 1890
                 E +    RLH   +    IQRQLQ +E R   LE RGV +EK LR   G   +D 
Sbjct: 717  PALPGETVTSPVRLHPDYLSPEEIQRQLQDIERRLDALELRGVELEKRLRAAEGDDAEDS 776

Query: 1891 PKLMQEWFKLVQEKNAMVRYESELMIFARELELEDRQSRLQQELRERMAVEDHLKTEEEL 1950
              LM +WF L+ EK  ++R ESELM  ++   LE++Q  ++ ELR  MA  + LK+ +E 
Sbjct: 777  --LMVDWFWLIHEKQLLLRQESELMYKSKAQRLEEQQLDIEGELRRLMAKPEALKSLQER 834

Query: 1951 SEEKQILNEMLEVVEQRDSLVALLEEQRLREREEDKDL 1988
              E+++L + +  V  R  +V  L+E RLRE+EED+ L
Sbjct: 835  RREQELLEQYVSTVNDRSDIVDSLDEDRLREQEEDQML 872



 Score = 63.5 bits (153), Expect = 2e-09
 Identities = 122/486 (25%), Positives = 173/486 (35%), Gaps = 64/486 (13%)

Query: 1172 HSPSTEGPQLPPVPAATQEKSPEERLFPEPLLPKEKPKADAPSDLKAVHSPIRSQPVTLP 1231
            +SP+       P PAAT   S   R    P  P E   A  P++ K       S P+   
Sbjct: 293  NSPARASVPAAPNPAATSATSVHVR---SPARPSESRLAPTPTEGKVRPRVTNSSPMGWS 349

Query: 1232 EARTPVSPGSPQPQPPVAASTPPPSP-----LPICSQPQ------PSTEATVPSP--TQS 1278
             A    +  +  P  P +A  P P+       P  + PQ       ++ ATV  P  T S
Sbjct: 350  SAAPCTAAAASHPAVPPSAPDPRPATPQGGGAPRVAAPQTTLSSSSTSAATVDPPAWTPS 409

Query: 1279 PIRFQPAPAKTSTPLAPLPVQSQSDTKDRLGSPLAVDEALRRSDLVEEFWMKSAEIRRSL 1338
              R Q A  K     A  P  S S         L+ D +  ++      ++K A      
Sbjct: 410  ASRTQQARNKFFQTSAVPPGTSLSGRGPTPSLVLSKDSSKEQA----RNFLKQA------ 459

Query: 1339 GLTPVDRSKGPEPSFPTPAFRPVSLKSYSVEKSPQDEGLHLLKPL--SIPKRLGLPKPEG 1396
             L+ ++ +  P P  P+PA   V     S  K+   +   L KPL  S P+ LGLP    
Sbjct: 460  -LSALEEAGAPAPGRPSPATAAV---PSSQPKTEAPQASPLAKPLQSSSPRVLGLPSRME 515

Query: 1397 EPLSLPTPRSPSDRELRSAQEERRELSSSSGLGLHGSSSNMKTLGSQSFNTSDSAMLTPP 1456
             P  L T  +     L  A   RR L+ SSG+G  G+ S  K     +     S  LT  
Sbjct: 516  PPAPLSTSSTSQASALPPA--GRRNLAESSGVGRVGAGSRPKPEAPMA--KGKSTTLTQD 571

Query: 1457 SSPPPPPPPGEEPATLRRKLREAE---PNASVVPPPLPATWMRPPREPAQPPREEVRKSF 1513
             S        + PA  R  L+  +   P    + P  P     P     + PR +V  SF
Sbjct: 572  MSTSLQEGQEDGPAGWRANLKPVDRRSPAERTLKPKEPRALAEP--RAGEAPR-KVSGSF 628

Query: 1514 VESVEEIPFADDVEDTYDDKTEDSSLQEKFFTPP--------------SCWPRPEKPRHP 1559
              SV         + T    +   SL  +  +PP                W RPE P   
Sbjct: 629  AGSVHITLTPVRPDRTPRPASPGPSLPARSPSPPRRRRLAVPASLDVCDNWLRPEPPGQE 688

Query: 1560 PLA---KENGRLPALEGTLQPQKRGLPLVSAEAKELAEERMRAREKSVKSQALRDAMARQ 1616
                  KE  + P L+G     K G PL  A    L  E + +  +        + + RQ
Sbjct: 689  ARVQSWKEEEKKPHLQG-----KPGRPLSPANVPALPGETVTSPVRLHPDYLSPEEIQRQ 743

Query: 1617 LSRMQQ 1622
            L  +++
Sbjct: 744  LQDIER 749



 Score = 36.6 bits (83), Expect = 0.25
 Identities = 70/331 (21%), Positives = 114/331 (34%), Gaps = 50/331 (15%)

Query: 1153 QATSPIRSPQESALLFIPVHSPSTEGPQLPPVPAATQEKSPEERLFPEPLLPKEKPKADA 1212
            +A +P       A   +P   P TE PQ  P+    Q  SP     P  + P       +
Sbjct: 465  EAGAPAPGRPSPATAAVPSSQPKTEAPQASPLAKPLQSSSPRVLGLPSRMEPPAPLSTSS 524

Query: 1213 PSDLKAVHSPIRSQPVTLPEARTPVSPGS-PQPQPPVAASTPPPSPLPICSQPQPSTEAT 1271
             S   A+  P   + +        V  GS P+P+ P+A                 ST  T
Sbjct: 525  TSQASAL-PPAGRRNLAESSGVGRVGAGSRPKPEAPMAKG--------------KSTTLT 569

Query: 1272 VPSPTQSPIRFQPAPAKTSTPLAPLPVQSQSDTKDRLGSPLAVDE--ALRRSDLVEEFWM 1329
                T      +  PA     L P+  +S ++   +   P A+ E  A      V   + 
Sbjct: 570  QDMSTSLQEGQEDGPAGWRANLKPVDRRSPAERTLKPKEPRALAEPRAGEAPRKVSGSFA 629

Query: 1330 KSAEIRRSLGLTPVDRSKGPEPSFPTPAFRPVSLKSYSVEKSPQDEGLHLLKPLSIPKRL 1389
             S  I     LTPV   + P P+ P P+    S         P+   L +   L +    
Sbjct: 630  GSVHIT----LTPVRPDRTPRPASPGPSLPARS------PSPPRRRRLAVPASLDVCDNW 679

Query: 1390 GLPKPEGEPLSLPTPRSPSDRELRSAQEERRELSSSSGLGLHGSSSNMKTLGSQSFNTSD 1449
              P+P G+           +  ++S +EE ++       G   S +N+  L  ++     
Sbjct: 680  LRPEPPGQ-----------EARVQSWKEEEKKPHLQGKPGRPLSPANVPALPGETV---- 724

Query: 1450 SAMLTPPSSPPPPPPPGEEPATLRRKLREAE 1480
                   +SP    P    P  ++R+L++ E
Sbjct: 725  -------TSPVRLHPDYLSPEEIQRQLQDIE 748


>gi|31324577 molecule interacting with Rab13 [Homo sapiens]
          Length = 863

 Score =  123 bits (309), Expect = 2e-27
 Identities = 54/100 (54%), Positives = 77/100 (77%)

Query: 524 LLGWCQRQTDGYAGVNVTDLTMSWKSGLALCAIIHRYRPDLIDFDSLDEQNVEKNNQLAF 583
           LL WC+RQ +GY GV + DL+ S++ GLA CAI+HR+RPDL+DFDSL + NV +NN+LAF
Sbjct: 8   LLAWCRRQCEGYRGVEIRDLSSSFRDGLAFCAILHRHRPDLLDFDSLSKDNVFENNRLAF 67

Query: 584 DIAEKELGISPIMTGKEMASVGEPDKLSMVMYLTQFYEMF 623
           ++AEKELGI  ++   +M S+  PD LS++ Y++Q+Y  F
Sbjct: 68  EVAEKELGIPALLDPNDMVSMSVPDCLSIMTYVSQYYNHF 107



 Score =  123 bits (309), Expect = 2e-27
 Identities = 176/663 (26%), Positives = 266/663 (40%), Gaps = 104/663 (15%)

Query: 1348 GPEPSFPTPAFRPVSLKSYSVEKSPQDEGLHLLKPLSIPKRLG--LPKPEGEPLSLPTPR 1405
            G  PS   PA         S E  PQ       KP  +P +L      P G P   P   
Sbjct: 254  GGGPSSSAPAGAEADGPKASPEARPQIP----TKP-RVPGKLQELASPPAGRPTPAPRKA 308

Query: 1406 SPSDRELRSAQEERRELSSSSGLGLHGSSSNMKTLGSQSFNTSDSAMLTPPSSPPPP--- 1462
            S S          R  L   + +   GSSS +           +  +  P  +P P    
Sbjct: 309  SESTTPAPPTPRPRSSLQQENLVEQAGSSSLVNG------RLHELPVPKPRGTPKPSEGT 362

Query: 1463 PPPGEEPATLRRKLREAEPNASVVPPPLPATWMRPPREPAQPPREEVRKSFVESVEEIPF 1522
            P P ++P  +   L +AEP     P PLP +    P  P+Q  R+       E  +  P 
Sbjct: 363  PAPRKDPPWIT--LVQAEPKKK--PAPLPPS--SSPGPPSQDSRQVENGGTEEVAQPSPT 416

Query: 1523 ADDVEDTYDDKTEDSSLQEKFFTPPSCWPRPEKPRHPPLAKEN--GRLPALEGTLQPQKR 1580
            A      Y+   E+   +E+           E P  P LA     G   +   +L P   
Sbjct: 417  ASLESKPYNPFEEEEEDKEE-----------EAPAAPSLATSPALGHPESTPKSLHPWYG 465

Query: 1581 GLPLVSAEAKELAEERMRAREKSVKSQALRDAMARQLSRMQQMELASGAPRPRKASSAPS 1640
              P  S + K+    R   R  S    AL        SR+   E  S  P P  A S  S
Sbjct: 466  ITPTSSPKTKK----RPAPRAPSASPLALH------ASRLSHSEPPSATPSP--ALSVES 513

Query: 1641 QGKERRPDSPTRPTLRGSEEPTLKHEATSEEVLSPPSDSGGPDG-SFTSSEGSSGKSKKR 1699
               E    +     L    EP    +++SE  +  P   G P   S  SS  SSG+    
Sbjct: 514  LSSESASQTAGAELL----EPPAVPKSSSEPAVHAPGTPGNPVSLSTNSSLASSGE---- 565

Query: 1700 SSLFSPRRNKKEKKSKGEGRPPEKPSSNLLEEAAAKPKSLWKSVFSGYKKDKKKKADDKS 1759
              L  PR  +  + S G   P  + SS       AKP        SG          D+S
Sbjct: 566  --LVEPRVEQMPQASPGLA-PRTRGSSG---PQPAKP-------CSGATPTPLLLVGDRS 612

Query: 1760 CPSTPSSGATVDSGKHRVLPVVRAELQLR---RQLSFSEDSDLSSDDVLEKSSQKSR--R 1814
               +P S +               +LQ++   ++  F+     ++    +K+++ S+  R
Sbjct: 613  PVPSPGSSSP--------------QLQVKSSCKENPFNRKPSPAASPATKKATKGSKPVR 658

Query: 1815 EPRTYTEEELNAKLTRRVQKAARRQAKQEELKRLHRAQIIQRQLQQVEERQRRLEERGVA 1874
             P       L   + R+VQ  A +   +E+         I  ++  +E R   LE RGV 
Sbjct: 659  PPAPGHGFPL---IKRKVQ--ADQYIPEED---------IHGEMDTIERRLDALEHRGVL 704

Query: 1875 VEKALRGEAGMGKKDDPKLMQEWFKLVQEKNAMVRYESELMIFARELELEDRQSRLQQEL 1934
            +E+ LRG    G++DD  ++ +WFKL+ EK+ +VR ESEL+   ++  LE RQ+ ++ EL
Sbjct: 705  LEEKLRGGLNEGREDD--MLVDWFKLIHEKHLLVRRESELIYVFKQQNLEQRQADVEYEL 762

Query: 1935 RERMAVEDHLKTEEELSEEKQILNEMLEVVEQRDSLVALLEEQRLREREEDKDLEAAMLS 1994
            R  +   +   TEE+ + EK ++ E++ ++EQR++++  L+E R RE EEDK LEA +  
Sbjct: 763  RCLLNKPEKDWTEEDRAREKVLMQELVTLIEQRNAIINCLDEDRQREEEEDKMLEAMIKK 822

Query: 1995 KGF 1997
            K F
Sbjct: 823  KEF 825



 Score = 88.6 bits (218), Expect = 6e-17
 Identities = 133/566 (23%), Positives = 198/566 (34%), Gaps = 88/566 (15%)

Query: 761  SDTCYFCQKRVYVMERLSAEGKFFHRSCFKCEYCATTLRLSAYAYDIEDGKFYCKPHYCY 820
            S TC  CQ+ V++++R  A+G+ +HR CF+C  C++TL   AY    E+G F C  H C 
Sbjct: 161  SSTCAACQQHVHLVQRYLADGRLYHRHCFRCRRCSSTLLPGAYENGPEEGTFVCAEH-CA 219

Query: 821  RLS-GYAQRKRPAVAPLSGKEAKGPLQDGATTDANGRANAVASSTERTPGSGVNGLEEPS 879
            RL  G     RP       ++ +  L + A     G  ++ A +     G   +    P 
Sbjct: 220  RLGPGTRSGTRPGPFSQPKQQHQQQLAEDAKDVPGGGPSSSAPAGAEADGPKASPEARPQ 279

Query: 880  IAKRLRGTPERIELENYRLSLRQAEALQEVPEETQAEHNLSSVLDTGAEEDVASSSSESE 939
            I  + R  P +++      + R   A ++  E T           +  +E++   +  S 
Sbjct: 280  IPTKPR-VPGKLQELASPPAGRPTPAPRKASESTTPAPPTPRPRSSLQQENLVEQAGSSS 338

Query: 940  MEEEGEEE--EEEPRLPPSDLGGV-------PWKEAVRIHALLKGKSEEELEASKSFGPG 990
            +      E    +PR  P    G        PW   V+       K    L  S S GP 
Sbjct: 339  LVNGRLHELPVPKPRGTPKPSEGTPAPRKDPPWITLVQAE---PKKKPAPLPPSSSPGPP 395

Query: 991  NEEEEEEEEEYEEEEEEDYDEEEEESSEAGNQRLQQVMHAADPLEIQADVHWTHIREREE 1050
            +++  + E    EE  +       ES               +P E           E E+
Sbjct: 396  SQDSRQVENGGTEEVAQPSPTASLESK------------PYNPFE----------EEEED 433

Query: 1051 EERMAPASESSASGAPLDENDLEEDVDSEPAEIEGEAAEDGDPGDTGAELDDDQHWSDSP 1110
            +E  APA+ S A+   L                       G P  T   L     +  +P
Sbjct: 434  KEEEAPAAPSLATSPAL-----------------------GHPESTPKSL--HPWYGITP 468

Query: 1111 SDADRELRLPCP-AEGEAELELRVSEDEEKLPASPKHQERGPSQATSPIRSPQESALLFI 1169
            + + +  + P P A   + L L  S      P S       PS A S      ESA    
Sbjct: 469  TSSPKTKKRPAPRAPSASPLALHASRLSHSEPPSAT-----PSPALSVESLSSESA---- 519

Query: 1170 PVHSPSTEGPQLPPVPAATQEKSPEERLFPEPLLPKEKPKADAPSDLKAVHSPIRSQPVT 1229
                  T G +L   PA    KS  E     P  P         S L +    +  +   
Sbjct: 520  ----SQTAGAELLEPPAV--PKSSSEPAVHAPGTPGNPVSLSTNSSLASSGELVEPRVEQ 573

Query: 1230 LPEARTPVSP---GSPQPQPPVAASTPPPSPLPICSQPQPSTEATVPSPTQSPIRFQPAP 1286
            +P+A   ++P   GS  PQP    S   P+PL +     P     VPSP  S  + Q   
Sbjct: 574  MPQASPGLAPRTRGSSGPQPAKPCSGATPTPLLLVGDRSP-----VPSPGSSSPQLQVKS 628

Query: 1287 AKTSTPL--APLPVQSQSDTKDRLGS 1310
            +    P    P P  S +  K   GS
Sbjct: 629  SCKENPFNRKPSPAASPATKKATKGS 654



 Score = 63.2 bits (152), Expect = 3e-09
 Identities = 104/439 (23%), Positives = 163/439 (37%), Gaps = 53/439 (12%)

Query: 1122 PAEGEAELELRVSEDEEKLPASP----KHQERGPSQATSPIRSPQESALLFIPVHSPSTE 1177
            PA  EA+      E   ++P  P    K QE     A  P  +P++++         +T 
Sbjct: 262  PAGAEADGPKASPEARPQIPTKPRVPGKLQELASPPAGRPTPAPRKAS-------ESTTP 314

Query: 1178 GPQLPPVPAATQEKSPEERLFPEPL-------LPKEKPKADAPSDLKAVHSPIRSQP-VT 1229
             P  P   ++ Q+++  E+     L       LP  KP+   P   +   +P +  P +T
Sbjct: 315  APPTPRPRSSLQQENLVEQAGSSSLVNGRLHELPVPKPRG-TPKPSEGTPAPRKDPPWIT 373

Query: 1230 LPEARTPVSPGSPQPQPPVAASTPPPSPLPICSQ------PQPSTEATVPSPTQSPIRFQ 1283
            L +A     P    P PP ++  PP                QPS  A++ S   +P   +
Sbjct: 374  LVQAEPKKKPA---PLPPSSSPGPPSQDSRQVENGGTEEVAQPSPTASLESKPYNPFEEE 430

Query: 1284 PAPAKTSTPLAPLPVQSQSDTKDRLGSPLAVDEALRRSDLVEEFWMKSAEIR---RSLGL 1340
                +   P AP        T   LG P +  ++L     +        + R   R+   
Sbjct: 431  EEDKEEEAPAAP-----SLATSPALGHPESTPKSLHPWYGITPTSSPKTKKRPAPRAPSA 485

Query: 1341 TPV----DRSKGPEPSFPTPAFRPVSLKSYSVEKSPQDEGLHLLKPLSIPK-----RLGL 1391
            +P+     R    EP   TP+   +S++S S E + Q  G  LL+P ++PK      +  
Sbjct: 486  SPLALHASRLSHSEPPSATPS-PALSVESLSSESASQTAGAELLEPPAVPKSSSEPAVHA 544

Query: 1392 PKPEGEPLSLPTPRS-PSDRELRSAQEERRELSSSSGLGLHGSSSNMKTLGSQSFNTSDS 1450
            P   G P+SL T  S  S  EL   + E+   +S         SS  +     S  T   
Sbjct: 545  PGTPGNPVSLSTNSSLASSGELVEPRVEQMPQASPGLAPRTRGSSGPQPAKPCSGATPTP 604

Query: 1451 AMLTPPSSPPPPPPPGEEPATLRRKLREAEPNASVVPPPLPAT-----WMRPPREPAQPP 1505
             +L    SP P P        ++   +E   N    P   PAT       +P R PA   
Sbjct: 605  LLLVGDRSPVPSPGSSSPQLQVKSSCKENPFNRKPSPAASPATKKATKGSKPVRPPAPGH 664

Query: 1506 REEVRKSFVESVEEIPFAD 1524
               + K  V++ + IP  D
Sbjct: 665  GFPLIKRKVQADQYIPEED 683


>gi|217330570 EH domain binding protein 1 isoform 2 [Homo sapiens]
          Length = 1196

 Score =  108 bits (269), Expect = 7e-23
 Identities = 100/385 (25%), Positives = 179/385 (46%), Gaps = 29/385 (7%)

Query: 1610 RDAMARQLSRMQQMELASGAPRPRKASSAPSQGKERRPDSPTRPTLRGSEEPTLKHEATS 1669
            +D   R+  R +  +L + A    K S  PS G+        R    G E   ++ + T+
Sbjct: 822  QDEERRRQLRERARQLIAEARSGVKMSELPSYGEMAAEKLKERSKASGDENDNIEID-TN 880

Query: 1670 EEVLSPPSDSGGPDGSFTSSEGSSGKSKKRSSLFSPRRNKKEKKSKGEGRPPEKPSSNLL 1729
            EE+         P+G      G    +   + L +P +N K    K +     +P     
Sbjct: 881  EEI---------PEGFVVG--GGDELTNLENDLDTPEQNSKLVDLKLKKLLEVQPQVANS 929

Query: 1730 EEAAAKPKSLWKSVFSGYKKDKKKKADDKSCPSTPSSGATVDSGKHRVLPVVRAELQLRR 1789
              +AA+     K+V    ++D K   +D     T     T +  ++ V+    + ++  +
Sbjct: 930  PSSAAQ-----KAVTESSEQDMKSGTEDLR---TERLQKTTERFRNPVVFSKDSTVRKTQ 981

Query: 1790 QLSFSEDSDLSSDDVLEKSSQKSRREPRTYTEEELNAKLTRRVQKAARRQAKQEELKRLH 1849
              SFS+      ++  E   Q+S +E      EE  A +T   +K +  +   +  K   
Sbjct: 982  LQSFSQ----YIENRPEMKRQRSIQEDTKKGNEE-KAAITETQRKPSEDEVLNKGFK--D 1034

Query: 1850 RAQIIQRQLQQVEERQRRLEERGVAVEKALRG--EAGMGKKDDPKLMQEWFKLVQEKNAM 1907
             +Q +  +L  +E  Q++++ R   VEK LR   + G   +++  +MQEWF LV +KNA+
Sbjct: 1035 TSQYVVGELAALENEQKQIDTRAALVEKRLRYLMDTGRNTEEEEAMMQEWFMLVNKKNAL 1094

Query: 1908 VRYESELMIFARELELEDRQSRLQQELRERMAVEDHLKTEEELSEEKQILNEMLEVVEQR 1967
            +R  ++L +  +E +LE R   L +ELR  +A+ED  KTE +   E+ +L+E++ +V +R
Sbjct: 1095 IRRMNQLSLLEKEHDLERRYELLNRELRAMLAIEDWQKTEAQKRREQLLLDELVALVNKR 1154

Query: 1968 DSLVALLEEQRLREREEDKDLEAAM 1992
            D+LV  L+ Q  +  EED+ LE  +
Sbjct: 1155 DALVRDLDAQEKQAEEEDEHLERTL 1179



 Score = 97.1 bits (240), Expect = 2e-19
 Identities = 47/115 (40%), Positives = 75/115 (65%), Gaps = 3/115 (2%)

Query: 509 TPKLTRNESVARSSKLLGWCQRQTDGYAGVNVTDLTMSWKSGLALCAIIHRYRPDLIDFD 568
           +P L R  + ++S  LL WC+  T  Y GV +T+ T SW++GL+ CAI+H +RPDLID+ 
Sbjct: 401 SPVLGRKPNASQS--LLVWCKEVTKNYRGVKITNFTTSWRNGLSFCAILHHFRPDLIDYK 458

Query: 569 SLDEQNVEKNNQLAFDIAEKELGISPIMTGKEMASVGEPDKLSMVMYLTQFYEMF 623
           SL+ Q++++NN+ A+D     +GIS ++   +M  +  PDKL+++ YL Q    F
Sbjct: 459 SLNPQDIKENNKKAYD-GFASIGISRLLEPSDMVLLAIPDKLTVMTYLYQIRAHF 512



 Score = 32.0 bits (71), Expect = 6.2
 Identities = 34/198 (17%), Positives = 81/198 (40%), Gaps = 21/198 (10%)

Query: 1800 SSDDVLEKSSQKSRREPRTYTEEELNAKLTRRVQKAARRQAKQEELKRLHRAQIIQRQLQ 1859
            SS+  ++  ++  R E    T E     +        R+   Q   + +     ++RQ  
Sbjct: 941  SSEQDMKSGTEDLRTERLQKTTERFRNPVVFSKDSTVRKTQLQSFSQYIENRPEMKRQRS 1000

Query: 1860 QVEERQRRLEERGVAVEKALRGEAGMGKKDDPKLMQEWFKLVQEK--NAMVRYESELMIF 1917
              E+ ++  EE+    E          K  + +++ + FK   +     +   E+E    
Sbjct: 1001 IQEDTKKGNEEKAAITET-------QRKPSEDEVLNKGFKDTSQYVVGELAALENE---- 1049

Query: 1918 ARELELEDRQSRLQQELRERMAVEDHLKTEEELSEEKQILNEMLEVVEQRDSLVALLEEQ 1977
              + +++ R + +++ LR  M       T     EE+ ++ E   +V ++++L+  + + 
Sbjct: 1050 --QKQIDTRAALVEKRLRYLM------DTGRNTEEEEAMMQEWFMLVNKKNALIRRMNQL 1101

Query: 1978 RLREREEDKDLEAAMLSK 1995
             L E+E D +    +L++
Sbjct: 1102 SLLEKEHDLERRYELLNR 1119


>gi|217330568 EH domain binding protein 1 isoform 1 [Homo sapiens]
          Length = 1231

 Score =  108 bits (269), Expect = 7e-23
 Identities = 100/385 (25%), Positives = 179/385 (46%), Gaps = 29/385 (7%)

Query: 1610 RDAMARQLSRMQQMELASGAPRPRKASSAPSQGKERRPDSPTRPTLRGSEEPTLKHEATS 1669
            +D   R+  R +  +L + A    K S  PS G+        R    G E   ++ + T+
Sbjct: 857  QDEERRRQLRERARQLIAEARSGVKMSELPSYGEMAAEKLKERSKASGDENDNIEID-TN 915

Query: 1670 EEVLSPPSDSGGPDGSFTSSEGSSGKSKKRSSLFSPRRNKKEKKSKGEGRPPEKPSSNLL 1729
            EE+         P+G      G    +   + L +P +N K    K +     +P     
Sbjct: 916  EEI---------PEGFVVG--GGDELTNLENDLDTPEQNSKLVDLKLKKLLEVQPQVANS 964

Query: 1730 EEAAAKPKSLWKSVFSGYKKDKKKKADDKSCPSTPSSGATVDSGKHRVLPVVRAELQLRR 1789
              +AA+     K+V    ++D K   +D     T     T +  ++ V+    + ++  +
Sbjct: 965  PSSAAQ-----KAVTESSEQDMKSGTEDLR---TERLQKTTERFRNPVVFSKDSTVRKTQ 1016

Query: 1790 QLSFSEDSDLSSDDVLEKSSQKSRREPRTYTEEELNAKLTRRVQKAARRQAKQEELKRLH 1849
              SFS+      ++  E   Q+S +E      EE  A +T   +K +  +   +  K   
Sbjct: 1017 LQSFSQ----YIENRPEMKRQRSIQEDTKKGNEE-KAAITETQRKPSEDEVLNKGFK--D 1069

Query: 1850 RAQIIQRQLQQVEERQRRLEERGVAVEKALRG--EAGMGKKDDPKLMQEWFKLVQEKNAM 1907
             +Q +  +L  +E  Q++++ R   VEK LR   + G   +++  +MQEWF LV +KNA+
Sbjct: 1070 TSQYVVGELAALENEQKQIDTRAALVEKRLRYLMDTGRNTEEEEAMMQEWFMLVNKKNAL 1129

Query: 1908 VRYESELMIFARELELEDRQSRLQQELRERMAVEDHLKTEEELSEEKQILNEMLEVVEQR 1967
            +R  ++L +  +E +LE R   L +ELR  +A+ED  KTE +   E+ +L+E++ +V +R
Sbjct: 1130 IRRMNQLSLLEKEHDLERRYELLNRELRAMLAIEDWQKTEAQKRREQLLLDELVALVNKR 1189

Query: 1968 DSLVALLEEQRLREREEDKDLEAAM 1992
            D+LV  L+ Q  +  EED+ LE  +
Sbjct: 1190 DALVRDLDAQEKQAEEEDEHLERTL 1214



 Score = 97.1 bits (240), Expect = 2e-19
 Identities = 47/115 (40%), Positives = 75/115 (65%), Gaps = 3/115 (2%)

Query: 509 TPKLTRNESVARSSKLLGWCQRQTDGYAGVNVTDLTMSWKSGLALCAIIHRYRPDLIDFD 568
           +P L R  + ++S  LL WC+  T  Y GV +T+ T SW++GL+ CAI+H +RPDLID+ 
Sbjct: 436 SPVLGRKPNASQS--LLVWCKEVTKNYRGVKITNFTTSWRNGLSFCAILHHFRPDLIDYK 493

Query: 569 SLDEQNVEKNNQLAFDIAEKELGISPIMTGKEMASVGEPDKLSMVMYLTQFYEMF 623
           SL+ Q++++NN+ A+D     +GIS ++   +M  +  PDKL+++ YL Q    F
Sbjct: 494 SLNPQDIKENNKKAYD-GFASIGISRLLEPSDMVLLAIPDKLTVMTYLYQIRAHF 547



 Score = 32.0 bits (71), Expect = 6.2
 Identities = 34/198 (17%), Positives = 81/198 (40%), Gaps = 21/198 (10%)

Query: 1800 SSDDVLEKSSQKSRREPRTYTEEELNAKLTRRVQKAARRQAKQEELKRLHRAQIIQRQLQ 1859
            SS+  ++  ++  R E    T E     +        R+   Q   + +     ++RQ  
Sbjct: 976  SSEQDMKSGTEDLRTERLQKTTERFRNPVVFSKDSTVRKTQLQSFSQYIENRPEMKRQRS 1035

Query: 1860 QVEERQRRLEERGVAVEKALRGEAGMGKKDDPKLMQEWFKLVQEK--NAMVRYESELMIF 1917
              E+ ++  EE+    E          K  + +++ + FK   +     +   E+E    
Sbjct: 1036 IQEDTKKGNEEKAAITET-------QRKPSEDEVLNKGFKDTSQYVVGELAALENE---- 1084

Query: 1918 ARELELEDRQSRLQQELRERMAVEDHLKTEEELSEEKQILNEMLEVVEQRDSLVALLEEQ 1977
              + +++ R + +++ LR  M       T     EE+ ++ E   +V ++++L+  + + 
Sbjct: 1085 --QKQIDTRAALVEKRLRYLM------DTGRNTEEEEAMMQEWFMLVNKKNALIRRMNQL 1136

Query: 1978 RLREREEDKDLEAAMLSK 1995
             L E+E D +    +L++
Sbjct: 1137 SLLEKEHDLERRYELLNR 1154


>gi|217330574 EH domain binding protein 1 isoform 3 [Homo sapiens]
          Length = 1160

 Score =  105 bits (263), Expect = 3e-22
 Identities = 80/290 (27%), Positives = 143/290 (49%), Gaps = 20/290 (6%)

Query: 1722 EKPSSNLLEEAAAKPKSLWKSVFSGYKKDKKKKADDKSCPSTPSSGATVDSGKH------ 1775
            E  +  L E + A  +   K V    KK  + +    + PS+ +  A  +S +       
Sbjct: 855  EMAAEKLKERSKASGEQNSKLVDLKLKKLLEVQPQVANSPSSAAQKAVTESSEQDMKSGT 914

Query: 1776 ---RVLPVVRAELQLRRQLSFSEDSDLSSDDVLEKSSQKSRREPRTYTEEELNAKLTR-R 1831
               R   + +   + R  + FS+DS +     L+  SQ     P    +  +     +  
Sbjct: 915  EDLRTERLQKTTERFRNPVVFSKDSTVRKTQ-LQSFSQYIENRPEMKRQRSIQEDTKKGN 973

Query: 1832 VQKAA-----RRQAKQEELKRLHR--AQIIQRQLQQVEERQRRLEERGVAVEKALRG--E 1882
             +KAA     R+ ++ E L +  +  +Q +  +L  +E  Q++++ R   VEK LR   +
Sbjct: 974  EEKAAITETQRKPSEDEVLNKGFKDTSQYVVGELAALENEQKQIDTRAALVEKRLRYLMD 1033

Query: 1883 AGMGKKDDPKLMQEWFKLVQEKNAMVRYESELMIFARELELEDRQSRLQQELRERMAVED 1942
             G   +++  +MQEWF LV +KNA++R  ++L +  +E +LE R   L +ELR  +A+ED
Sbjct: 1034 TGRNTEEEEAMMQEWFMLVNKKNALIRRMNQLSLLEKEHDLERRYELLNRELRAMLAIED 1093

Query: 1943 HLKTEEELSEEKQILNEMLEVVEQRDSLVALLEEQRLREREEDKDLEAAM 1992
              KTE +   E+ +L+E++ +V +RD+LV  L+ Q  +  EED+ LE  +
Sbjct: 1094 WQKTEAQKRREQLLLDELVALVNKRDALVRDLDAQEKQAEEEDEHLERTL 1143



 Score = 97.1 bits (240), Expect = 2e-19
 Identities = 47/115 (40%), Positives = 75/115 (65%), Gaps = 3/115 (2%)

Query: 509 TPKLTRNESVARSSKLLGWCQRQTDGYAGVNVTDLTMSWKSGLALCAIIHRYRPDLIDFD 568
           +P L R  + ++S  LL WC+  T  Y GV +T+ T SW++GL+ CAI+H +RPDLID+ 
Sbjct: 401 SPVLGRKPNASQS--LLVWCKEVTKNYRGVKITNFTTSWRNGLSFCAILHHFRPDLIDYK 458

Query: 569 SLDEQNVEKNNQLAFDIAEKELGISPIMTGKEMASVGEPDKLSMVMYLTQFYEMF 623
           SL+ Q++++NN+ A+D     +GIS ++   +M  +  PDKL+++ YL Q    F
Sbjct: 459 SLNPQDIKENNKKAYD-GFASIGISRLLEPSDMVLLAIPDKLTVMTYLYQIRAHF 512



 Score = 33.1 bits (74), Expect = 2.8
 Identities = 52/294 (17%), Positives = 116/294 (39%), Gaps = 31/294 (10%)

Query: 1707 RNKKEKKSKGEGRPPEKPSSNLLEEAAAKPKSLWKSVFSGYKKDKKKKADDKSCPSTPSS 1766
            R   +++ +   R   + +  L+ EA +  K    S    Y +   +K  ++S  S   +
Sbjct: 816  RQLSDQQDEERRRQLRERARQLIAEARSGVKM---SELPSYGEMAAEKLKERSKASGEQN 872

Query: 1767 GATVDSGKHRVL---PVVRAELQLRRQLSFSEDSDLSSDDVLEKSSQKSRREPRTYTEEE 1823
               VD    ++L   P V        Q + +E    SS+  ++  ++  R E    T E 
Sbjct: 873  SKLVDLKLKKLLEVQPQVANSPSSAAQKAVTE----SSEQDMKSGTEDLRTERLQKTTER 928

Query: 1824 LNAKLTRRVQKAARRQAKQEELKRLHRAQIIQRQLQQVEERQRRLEERGVAVEKALRGEA 1883
                +        R+   Q   + +     ++RQ    E+ ++  EE+    E       
Sbjct: 929  FRNPVVFSKDSTVRKTQLQSFSQYIENRPEMKRQRSIQEDTKKGNEEKAAITET------ 982

Query: 1884 GMGKKDDPKLMQEWFKLVQEK--NAMVRYESELMIFARELELEDRQSRLQQELRERMAVE 1941
               K  + +++ + FK   +     +   E+E      + +++ R + +++ LR  M   
Sbjct: 983  -QRKPSEDEVLNKGFKDTSQYVVGELAALENE------QKQIDTRAALVEKRLRYLM--- 1032

Query: 1942 DHLKTEEELSEEKQILNEMLEVVEQRDSLVALLEEQRLREREEDKDLEAAMLSK 1995
                T     EE+ ++ E   +V ++++L+  + +  L E+E D +    +L++
Sbjct: 1033 ---DTGRNTEEEEAMMQEWFMLVNKKNALIRRMNQLSLLEKEHDLERRYELLNR 1083


>gi|217330572 EH domain binding protein 1 isoform 3 [Homo sapiens]
          Length = 1160

 Score =  105 bits (263), Expect = 3e-22
 Identities = 80/290 (27%), Positives = 143/290 (49%), Gaps = 20/290 (6%)

Query: 1722 EKPSSNLLEEAAAKPKSLWKSVFSGYKKDKKKKADDKSCPSTPSSGATVDSGKH------ 1775
            E  +  L E + A  +   K V    KK  + +    + PS+ +  A  +S +       
Sbjct: 855  EMAAEKLKERSKASGEQNSKLVDLKLKKLLEVQPQVANSPSSAAQKAVTESSEQDMKSGT 914

Query: 1776 ---RVLPVVRAELQLRRQLSFSEDSDLSSDDVLEKSSQKSRREPRTYTEEELNAKLTR-R 1831
               R   + +   + R  + FS+DS +     L+  SQ     P    +  +     +  
Sbjct: 915  EDLRTERLQKTTERFRNPVVFSKDSTVRKTQ-LQSFSQYIENRPEMKRQRSIQEDTKKGN 973

Query: 1832 VQKAA-----RRQAKQEELKRLHR--AQIIQRQLQQVEERQRRLEERGVAVEKALRG--E 1882
             +KAA     R+ ++ E L +  +  +Q +  +L  +E  Q++++ R   VEK LR   +
Sbjct: 974  EEKAAITETQRKPSEDEVLNKGFKDTSQYVVGELAALENEQKQIDTRAALVEKRLRYLMD 1033

Query: 1883 AGMGKKDDPKLMQEWFKLVQEKNAMVRYESELMIFARELELEDRQSRLQQELRERMAVED 1942
             G   +++  +MQEWF LV +KNA++R  ++L +  +E +LE R   L +ELR  +A+ED
Sbjct: 1034 TGRNTEEEEAMMQEWFMLVNKKNALIRRMNQLSLLEKEHDLERRYELLNRELRAMLAIED 1093

Query: 1943 HLKTEEELSEEKQILNEMLEVVEQRDSLVALLEEQRLREREEDKDLEAAM 1992
              KTE +   E+ +L+E++ +V +RD+LV  L+ Q  +  EED+ LE  +
Sbjct: 1094 WQKTEAQKRREQLLLDELVALVNKRDALVRDLDAQEKQAEEEDEHLERTL 1143



 Score = 97.1 bits (240), Expect = 2e-19
 Identities = 47/115 (40%), Positives = 75/115 (65%), Gaps = 3/115 (2%)

Query: 509 TPKLTRNESVARSSKLLGWCQRQTDGYAGVNVTDLTMSWKSGLALCAIIHRYRPDLIDFD 568
           +P L R  + ++S  LL WC+  T  Y GV +T+ T SW++GL+ CAI+H +RPDLID+ 
Sbjct: 401 SPVLGRKPNASQS--LLVWCKEVTKNYRGVKITNFTTSWRNGLSFCAILHHFRPDLIDYK 458

Query: 569 SLDEQNVEKNNQLAFDIAEKELGISPIMTGKEMASVGEPDKLSMVMYLTQFYEMF 623
           SL+ Q++++NN+ A+D     +GIS ++   +M  +  PDKL+++ YL Q    F
Sbjct: 459 SLNPQDIKENNKKAYD-GFASIGISRLLEPSDMVLLAIPDKLTVMTYLYQIRAHF 512



 Score = 33.1 bits (74), Expect = 2.8
 Identities = 52/294 (17%), Positives = 116/294 (39%), Gaps = 31/294 (10%)

Query: 1707 RNKKEKKSKGEGRPPEKPSSNLLEEAAAKPKSLWKSVFSGYKKDKKKKADDKSCPSTPSS 1766
            R   +++ +   R   + +  L+ EA +  K    S    Y +   +K  ++S  S   +
Sbjct: 816  RQLSDQQDEERRRQLRERARQLIAEARSGVKM---SELPSYGEMAAEKLKERSKASGEQN 872

Query: 1767 GATVDSGKHRVL---PVVRAELQLRRQLSFSEDSDLSSDDVLEKSSQKSRREPRTYTEEE 1823
               VD    ++L   P V        Q + +E    SS+  ++  ++  R E    T E 
Sbjct: 873  SKLVDLKLKKLLEVQPQVANSPSSAAQKAVTE----SSEQDMKSGTEDLRTERLQKTTER 928

Query: 1824 LNAKLTRRVQKAARRQAKQEELKRLHRAQIIQRQLQQVEERQRRLEERGVAVEKALRGEA 1883
                +        R+   Q   + +     ++RQ    E+ ++  EE+    E       
Sbjct: 929  FRNPVVFSKDSTVRKTQLQSFSQYIENRPEMKRQRSIQEDTKKGNEEKAAITET------ 982

Query: 1884 GMGKKDDPKLMQEWFKLVQEK--NAMVRYESELMIFARELELEDRQSRLQQELRERMAVE 1941
               K  + +++ + FK   +     +   E+E      + +++ R + +++ LR  M   
Sbjct: 983  -QRKPSEDEVLNKGFKDTSQYVVGELAALENE------QKQIDTRAALVEKRLRYLM--- 1032

Query: 1942 DHLKTEEELSEEKQILNEMLEVVEQRDSLVALLEEQRLREREEDKDLEAAMLSK 1995
                T     EE+ ++ E   +V ++++L+  + +  L E+E D +    +L++
Sbjct: 1033 ---DTGRNTEEEEAMMQEWFMLVNKKNALIRRMNQLSLLEKEHDLERRYELLNR 1083


>gi|55741677 SET domain containing 1A [Homo sapiens]
          Length = 1707

 Score =  104 bits (259), Expect = 1e-21
 Identities = 155/679 (22%), Positives = 244/679 (35%), Gaps = 136/679 (20%)

Query: 837  SGKEAKGPLQDGATTDANG--------RANAVASSTERTPGSGVNGLEEPSIAKRLRGTP 888
            S +E   P Q+ A   A          +   + S  +     G  G+E  +    LRG  
Sbjct: 829  SKEEKAKPFQNAAKQQAKEEDKEKTKLKEPGLLSLVDWAKSGGTTGIEAFAFGSGLRGA- 887

Query: 889  ERIELENYRLSLRQAEALQEVPEETQAEHNLSSVLDTGAEEDVASSSSESEMEEEGEEEE 948
              + L ++++  ++   + E  EE +   +      T AEED      E E  E G    
Sbjct: 888  --LRLPSFKVKRKEPSEISEASEEKRPRPS------TPAEEDEDDPEQEKEAGEPGRPGT 939

Query: 949  EEPRLPPSDLGGVPWKEAVRIHALLKGKSEEELEASKSFGPGNEEEEEEEEEYEEEEEED 1008
            + P+                     +GK++ +   S +     EE  +E    ++EE+++
Sbjct: 940  KPPKRDEE-----------------RGKTQGKHRKSFALDSEGEEASQESSSEKDEEDDE 982

Query: 1009 YDEEEEESSEAGNQRLQQVMHAADPLEIQADVHWTHIREREEEERMAPASESSASGAPLD 1068
             DEE+E+  EA +   ++                T + + E+EE     S+SS+  +   
Sbjct: 983  EDEEDEDREEAVDTTKKE----------------TEVSDGEDEE-----SDSSSKCSLYA 1021

Query: 1069 ENDLEEDV--DSEPAEIEGEAAEDGDPGDTGAELDDDQHWSDSPSDADRELRLPC----- 1121
            ++D E D   DSE +     ++       + +     +  S+   + +R   LP      
Sbjct: 1022 DSDGENDSTSDSESSSSSSSSSSSSSSSSSSSSSSSSESSSEDEEEEERPAALPSASPPP 1081

Query: 1122 ---PAEGEAELELRVSEDEEKLPASP-KHQERGPSQATSPIRSPQESALLFIPVHSPSTE 1177
               P    A +E+ V E     P +P   QE  P++   P      SA    P+  P  E
Sbjct: 1082 REVPVPTPAPVEVPVPERVAGSPVTPLPEQEASPARPAGPTEESPPSA----PLRPP--E 1135

Query: 1178 GPQLPPVPAATQEKSPEERLFPEPLLP--KEKPKADAPSDLKAVHSPIRSQPVTLPEART 1235
             P  PP PA   ++ P     P PLLP  K++ K  + S ++ V +P    P T P+A+ 
Sbjct: 1136 PPAGPPAPAPRPDERPSS---PIPLLPPPKKRRKTVSFSAIEVVPAP-EPPPATPPQAKF 1191

Query: 1236 PVSPGSPQPQ---------PPVAASTPPPSPLPIC----------------SQPQPSTEA 1270
            P       P+         P   AS     P  +                  + +P TE 
Sbjct: 1192 PGPASRKAPRGVERTIRNLPLDHASLVKSWPEEVSRGGRSRAGGRGRLTEEEEAEPGTEV 1251

Query: 1271 TVPSPTQSPIRFQPAPAKTSTPLAPLPVQSQSDTKDRLGSPLAVDEALRRSDLVEEFWMK 1330
             +       +     PA+   P  P    S++            DEA R   L+    + 
Sbjct: 1252 DLAVLADLAL----TPARRGLPALPAVEDSEATETS--------DEAERPRPLLSHILL- 1298

Query: 1331 SAEIRRSLGLTPVDRSKGPEPSFPTPAFRPVSLKSYSVEKSPQDEGLHLLKPLSIPKRLG 1390
              E   +L + P   +    P  P PA  P +L S     SP DE       L  P+ + 
Sbjct: 1299 --EHNYALAVKPTPPAPALRPPEPVPA--PAALFS-----SPADE------VLEAPEVVV 1343

Query: 1391 LPKPEGEPLSLPTPRSPSDRELRSAQEERRELSSSSGLGLHGSSSNMKTLGSQSFNTSDS 1450
                E +P  L   R   + E     EE  E SS S      SS     L  +S   S +
Sbjct: 1344 AEAEEPKPQQLQQQREEGEEEGEEEGEEEEEESSDSS----SSSDGEGALRRRSLR-SHA 1398

Query: 1451 AMLTPPSSPPPPPPPGEEP 1469
                PP  PPPPPP   EP
Sbjct: 1399 RRRRPPPPPPPPPPRAYEP 1417



 Score = 51.6 bits (122), Expect = 8e-06
 Identities = 144/650 (22%), Positives = 204/650 (31%), Gaps = 125/650 (19%)

Query: 1236 PVSPGSPQPQP--PVAASTPPPSPLPICSQPQPSTEATVPSPTQSPIRFQPAPAKTSTPL 1293
            P  P  P  Q   P A+  PPP P     +P        PSP +  +R  P PA  +   
Sbjct: 414  PPEPSRPTDQDYRPPASEAPPPEP----PEPGGGGGGGGPSPEREEVRTSPRPASPARSG 469

Query: 1294 APLPVQSQSDTKDRLGSPLAVDEALRRSDLVEEFWMKSAEIRRSLGLTPVDRSKGPEPSF 1353
            +P P  +          P A     + S L     M   E R        D  +  E S 
Sbjct: 470  SPAPETTNESV------PFA-----QHSSLDSRIEMLLKEQRSKFSFLASDTEEEEENSS 518

Query: 1354 PTPAFRPVSLKSYSVEKSPQDEGLHLLKPLSIPKRLG--LPKPEGEPLSLPTPRSPSDRE 1411
                 R          + P   G     P   P       P   GEP         + RE
Sbjct: 519  MVLGARDTG------SEVPSGSGHGPCTPPPAPANFEDVAPTGSGEP--------GATRE 564

Query: 1412 LRSAQEERRELSSSSGLGLHGSSSNMKTLGSQSFNTSDSAMLTPPSSPPPPPPPGEEPAT 1471
               A  + +    SSG  +  S  +           S     TPP  PPPPPPP   P  
Sbjct: 565  SPKANGQNQASPCSSGDDMEISDDDR--------GGSPPPAPTPPQQPPPPPPPPPPPPP 616

Query: 1472 LRRKLREAEP--NASVVPPPLPATWMRPPREPAQPPREEVRKSFVESVEEIPFADDVEDT 1529
                L    P    + + PP P     PP  P  PP       FV S+E     D +   
Sbjct: 617  YLASLPLGYPPHQPAYLLPPRP-DGPPPPEYPPPPPPPPHIYDFVNSLE---LMDRLGAQ 672

Query: 1530 YDDKTEDSSLQEKFFT------------------PPSCWPRPEKPRHPPLAKENGRLPAL 1571
            +        +Q +  T                  P   +     P  PP     G   AL
Sbjct: 673  WGGMPMSFQMQTQMLTRLHQLRQGKGLIAASAGPPGGAFGEAFLPFPPPQEAAYGLPYAL 732

Query: 1572 -------EGTLQPQKRGLPLVSA-------------------EAKELAEERMR------A 1599
                    G    +   LP+  A                   E  ELAE +         
Sbjct: 733  YAQGQEGRGAYSREAYHLPMPMAAEPLPSSSVSGEEARLPPREEAELAEGKTLPTAGTVG 792

Query: 1600 REKSVKSQALRDAMARQLSRMQQMELASGA------PRPRKASSAPSQGKERRPDSPTRP 1653
            R  ++  Q ++  M R L+R     +A GA       +  KA    +  K++  +     
Sbjct: 793  RVLAMLVQEMKSIMQRDLNRKMVENVAFGAFDQWWESKEEKAKPFQNAAKQQAKEEDKEK 852

Query: 1654 TLRGSEEPTLKHEATSEEVLSPPSDSGGPDGSFTSSEGSSGKSKKRSSLFSPRRNKKEKK 1713
            T    +EP L         L   + SGG  G    + GS  +   R   F  +R +  + 
Sbjct: 853  T--KLKEPGLLS-------LVDWAKSGGTTGIEAFAFGSGLRGALRLPSFKVKRKEPSEI 903

Query: 1714 SKGEGRPPEKPSSNLLEEAAAKPKSLWKSVFSGYKKDKKKKADDKSCPSTPSSGATVDSG 1773
            S+       +PS+   EE    P+   ++   G    K  K D++        G T   G
Sbjct: 904  SEASEEKRPRPSTP-AEEDEDDPEQEKEAGEPGRPGTKPPKRDEE-------RGKT--QG 953

Query: 1774 KHRVLPVVRAELQLRRQLSFSEDSDLSSDDVLEKSSQKSRREPRTYTEEE 1823
            KHR    + +E +   Q S SE  +   +D  E    + R E    T++E
Sbjct: 954  KHRKSFALDSEGEEASQESSSEKDE---EDDEEDEEDEDREEAVDTTKKE 1000



 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 158/750 (21%), Positives = 234/750 (31%), Gaps = 125/750 (16%)

Query: 1046 REREEEERMAPASESSASGAPLD-------ENDLEEDVDSEPAEIEGEAAEDGDPGDTGA 1098
            R   EE   AP +E++A   P         E     D D  P   E    E  +PG  G 
Sbjct: 386  RATREEPPGAPFAENTAERFPPSYTSYLPPEPSRPTDQDYRPPASEAPPPEPPEPGGGGG 445

Query: 1099 ELDDDQHWSDSPSDADRELRL-PCPAEGEAELELRVSEDEEKLPASP------------K 1145
                       PS    E+R  P PA              E +P +             K
Sbjct: 446  --------GGGPSPEREEVRTSPRPASPARSGSPAPETTNESVPFAQHSSLDSRIEMLLK 497

Query: 1146 HQERGPSQATSPIRSPQESALLFIPVHSPSTEGPQ--------LPPVPAATQEKSPEERL 1197
             Q    S   S     +E++ + +      +E P          PP PA  ++ +P    
Sbjct: 498  EQRSKFSFLASDTEEEEENSSMVLGARDTGSEVPSGSGHGPCTPPPAPANFEDVAPTGS- 556

Query: 1198 FPEPLLPKEKPKADAPSDLKAVHSPIRSQPVTLPEARTPVSPGSPQPQPPVAASTPPPSP 1257
              EP   +E PKA+  +      SP  S      E       GSP P P      PPP P
Sbjct: 557  -GEPGATRESPKANGQNQA----SPCSSGDDM--EISDDDRGGSPPPAPTPPQQPPPPPP 609

Query: 1258 LPICSQPQPSTEATVP---SPTQSPIRFQPAPAKTSTPLAPLPVQSQSDTKDRLGSPLAV 1314
             P    P P   A++P    P Q      P P     P  P P        D + S   +
Sbjct: 610  PP---PPPPPYLASLPLGYPPHQPAYLLPPRPDGPPPPEYPPPPPPPPHIYDFVNSLELM 666

Query: 1315 DE-ALRRSDLVEEFWMKSA------EIRRSLGLTPVDRSKGPEPS--------FPTPAFR 1359
            D    +   +   F M++       ++R+  GL  +  S GP           FP P   
Sbjct: 667  DRLGAQWGGMPMSFQMQTQMLTRLHQLRQGKGL--IAASAGPPGGAFGEAFLPFPPPQEA 724

Query: 1360 PVSLKSYSVEKSPQDEGLHLLKPLSIPKRLGLPKPEGEPLSLPTPRSPSDRELRSAQEER 1419
               L      +  +  G +  +   +P  +         +S    R P   E   A+ + 
Sbjct: 725  AYGLPYALYAQGQEGRGAYSREAYHLPMPMAAEPLPSSSVSGEEARLPPREEAELAEGKT 784

Query: 1420 RELSSSSGLGLHGSSSNMKTLGSQSFN------TSDSAMLTPPSSPPPPPPPGEEPATLR 1473
               + + G  L      MK++  +  N       +  A      S      P +  A  +
Sbjct: 785  LPTAGTVGRVLAMLVQEMKSIMQRDLNRKMVENVAFGAFDQWWESKEEKAKPFQNAAKQQ 844

Query: 1474 RKLREAEPNASVVPPPLPATWMRPPREPAQPPREEVRKSFVESVEEIPFADDVEDTY--- 1530
             K  + E      P  L                +  +      +E   F   +       
Sbjct: 845  AKEEDKEKTKLKEPGLLSLV-------------DWAKSGGTTGIEAFAFGSGLRGALRLP 891

Query: 1531 ------DDKTEDSSLQEKFFTPPSCWPRPEKPRHPPLAKENGRLPALEGTLQPQKRGLPL 1584
                   + +E S   E+    PS  P  E    P   KE G  P   GT  P++     
Sbjct: 892  SFKVKRKEPSEISEASEEKRPRPST-PAEEDEDDPEQEKEAGE-PGRPGTKPPKRD---- 945

Query: 1585 VSAEAKELAEERMRAREKSVKSQALRDAMARQLSRMQQMELASGAPRPRKASSAPSQGKE 1644
                     EER + + K  KS AL D+   + S+    E +S             + +E
Sbjct: 946  ---------EERGKTQGKHRKSFAL-DSEGEEASQ----ESSSEKDEEDDEEDEEDEDRE 991

Query: 1645 RRPDSPTRPTLRGSEEPTLKHEATSEEVLSPPSDSGGPDGSFTSSEGSSGKSKKRSSLFS 1704
               D+  + T     E     E+ S    S  +DS G + S + SE SS  S   SS  S
Sbjct: 992  EAVDTTKKETEVSDGED---EESDSSSKCSLYADSDGENDSTSDSESSSSSSSSSSSSSS 1048

Query: 1705 PRRNKKEKKSKG-------EGRPPEKPSSN 1727
               +     S+        E RP   PS++
Sbjct: 1049 SSSSSSSSSSESSSEDEEEEERPAALPSAS 1078



 Score = 40.0 bits (92), Expect = 0.023
 Identities = 33/116 (28%), Positives = 43/116 (37%), Gaps = 19/116 (16%)

Query: 1406 SPSDRELRSAQEERRELSSSSGLGLHGSSSNMKTLGSQSFNTSDSAMLTPPSSPPPPPPP 1465
            S SD E  S+       SSSS      SSS+     S+     +     P +SPPP   P
Sbjct: 1029 STSDSESSSSSSSSSSSSSSSS---SSSSSSSSESSSEDEEEEERPAALPSASPPPREVP 1085

Query: 1466 GEEPATLRRKLREAEPNASVVPPP----------------LPATWMRPPREPAQPP 1505
               PA +   + E    + V P P                 P+  +RPP  PA PP
Sbjct: 1086 VPTPAPVEVPVPERVAGSPVTPLPEQEASPARPAGPTEESPPSAPLRPPEPPAGPP 1141



 Score = 37.0 bits (84), Expect = 0.19
 Identities = 77/389 (19%), Positives = 120/389 (30%), Gaps = 62/389 (15%)

Query: 1362 SLKSYSVEKSPQDEGLHLLKPLSIPKRLGLPKPEGEPLSLPTPRSPSDRELRSAQEERRE 1421
            S  S S  +  ++E      P + P    +P P   P+ +P P   +   +    E+   
Sbjct: 1055 SSSSESSSEDEEEEERPAALPSASPPPREVPVPTPAPVEVPVPERVAGSPVTPLPEQEAS 1114

Query: 1422 LSSSSGLGLHGSSSNMKTLGSQSFNTSDSAMLTPPSSPPPPPP----PGEEPAT------ 1471
             +  +G                +  +  SA L PP  P  PP     P E P++      
Sbjct: 1115 PARPAG---------------PTEESPPSAPLRPPEPPAGPPAPAPRPDERPSSPIPLLP 1159

Query: 1472 --LRRKLREAEPNASVVPPPLPATWMRPPREPAQPPREEVRKSFVESVEEIPFADDVEDT 1529
               +R+   +     VVP P P     P  +   P   +  +    ++  +P        
Sbjct: 1160 PPKKRRKTVSFSAIEVVPAPEPPPATPPQAKFPGPASRKAPRGVERTIRNLPL------- 1212

Query: 1530 YDDKTEDSSLQEKFFTPPSCWPRPEKPRHPPLAKENGRLPALEG--------TLQPQKRG 1581
                 + +SL + +    S   R        L +E    P  E          L P +RG
Sbjct: 1213 -----DHASLVKSWPEEVSRGGRSRAGGRGRLTEEEEAEPGTEVDLAVLADLALTPARRG 1267

Query: 1582 LPLVSA----EAKELAEERMRAREKSVKSQALRDAMARQLSRMQQMELASGAPRPRKASS 1637
            LP + A    EA E ++E  R R   + S  L       L     + +    P P     
Sbjct: 1268 LPALPAVEDSEATETSDEAERPR--PLLSHIL-------LEHNYALAVKPTPPAPALRPP 1318

Query: 1638 APSQGKERRPDSPTRPTLRGSEEPTLKHEATSEEVLSPPSDSGGPDG--SFTSSEGSSGK 1695
             P         SP    L   E    + E    + L    + G  +G       E  S  
Sbjct: 1319 EPVPAPAALFSSPADEVLEAPEVVVAEAEEPKPQQLQQQREEGEEEGEEEGEEEEEESSD 1378

Query: 1696 SKKRSSLFSPRRNKKEKKSKGEGRPPEKP 1724
            S   S      R +  +      RPP  P
Sbjct: 1379 SSSSSDGEGALRRRSLRSHARRRRPPPPP 1407


>gi|67782321 spectrin beta isoform a [Homo sapiens]
          Length = 2328

 Score =  103 bits (258), Expect = 1e-21
 Identities = 52/113 (46%), Positives = 75/113 (66%), Gaps = 3/113 (2%)

Query: 513 TRNESVARSSK--LLGWCQRQTDGYAGVNVTDLTMSWKSGLALCAIIHRYRPDLIDFDSL 570
           T+     RS+K  LL WCQ +T GY  VNVT+ T SWK GLA  A+IH++RPDLIDFD L
Sbjct: 166 TQEGRETRSAKDALLLWCQMKTAGYPHVNVTNFTSSWKDGLAFNALIHKHRPDLIDFDKL 225

Query: 571 DEQNVEKNNQLAFDIAEKELGISPIMTGKEMASVGEPDKLSMVMYLTQFYEMF 623
            + N   N + AF++AE++LGI P++  +++ +   PD+ S++ Y+  FY  F
Sbjct: 226 KDSNARHNLEHAFNVAERQLGIIPLLDPEDVFT-ENPDEKSIITYVVAFYHYF 277


>gi|67782319 spectrin beta isoform b [Homo sapiens]
          Length = 2137

 Score =  103 bits (258), Expect = 1e-21
 Identities = 52/113 (46%), Positives = 75/113 (66%), Gaps = 3/113 (2%)

Query: 513 TRNESVARSSK--LLGWCQRQTDGYAGVNVTDLTMSWKSGLALCAIIHRYRPDLIDFDSL 570
           T+     RS+K  LL WCQ +T GY  VNVT+ T SWK GLA  A+IH++RPDLIDFD L
Sbjct: 166 TQEGRETRSAKDALLLWCQMKTAGYPHVNVTNFTSSWKDGLAFNALIHKHRPDLIDFDKL 225

Query: 571 DEQNVEKNNQLAFDIAEKELGISPIMTGKEMASVGEPDKLSMVMYLTQFYEMF 623
            + N   N + AF++AE++LGI P++  +++ +   PD+ S++ Y+  FY  F
Sbjct: 226 KDSNARHNLEHAFNVAERQLGIIPLLDPEDVFT-ENPDEKSIITYVVAFYHYF 277


>gi|210032580 SET domain containing 1B [Homo sapiens]
          Length = 1923

 Score =  102 bits (253), Expect = 5e-21
 Identities = 168/678 (24%), Positives = 245/678 (36%), Gaps = 73/678 (10%)

Query: 925  TGAEEDVASSSSESEMEEEGEEEEEEP------RLPPSDLGGVPWKEA-VRIHALLKGKS 977
            +G ++ +  S+S  E +EE E E +         L   D  GV  +    R   L  G  
Sbjct: 975  SGDQKRLRPSTSVDEEDEESERERDRDMADTPCELAKRDPKGVGVRRRPARPLELDSGGE 1034

Query: 978  EEELEASKSFGPGNEEEEEEEEEYEEEEEEDYDEEEEESSEAGNQRLQQVMHAADPLEIQ 1037
            E+E E+        EEEEE EEE EEE+++D D ++ + SE  ++    +  A++  E  
Sbjct: 1035 EDEKESLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDESENDDED-TALSEASEKDEGD 1093

Query: 1038 ADVHWTHIREREEEERMAPASESSASGAPLDENDLEEDVDSEPAEIEGE----AAEDGDP 1093
            +D       E E    +   +E+++S    + ++ E   +S P+  E E    A E+ + 
Sbjct: 1094 SD-------EEETVSIVTSKAEATSSSESSESSEFESSSESSPSSSEDEEEVVAREEEEE 1146

Query: 1094 GDTGAELDDDQHWSDSPSDADRELRLPCPAEGEAELELRVSEDEEKLPASPKHQERGPSQ 1153
             +    + ++   S  P D +++      A G   ++    E+E  +       E  PS 
Sbjct: 1147 EEEEEMVAEESMASAGPEDFEQDGEEAALAPGAPAVDSLGMEEEVDIETEAVAPEERPSM 1206

Query: 1154 ATSP-----IRSPQESALLFIPVHSP--STEGPQL--PPVPAATQEKSPEERLFPEPLLP 1204
               P     +  P +S     P   P  S EG  L  P  PA   E  P       PL P
Sbjct: 1207 LDEPPLPVGVEEPADSR---EPPEEPGLSQEGAMLLSPEPPAKEVEARP-------PLSP 1256

Query: 1205 KEKPKADAPSDLK-AVHSPIRSQPVTLPEARTPVSPGSPQPQPPVA-ASTPPPSPLPICS 1262
            +  P+ D   + +  +  P+  QP  LP  R P  P SP P+P    AS P   P P+  
Sbjct: 1257 ERAPEHDLEVEPEPPMMLPLPLQP-PLPPPRPP-RPPSPPPEPETTDASHPSVPPEPLAE 1314

Query: 1263 QPQPSTEATVPSPTQSPIRFQPAPAKTSTPLAPLPVQSQSDTKDRLGSPLAVDEALRRSD 1322
               P T    P    S  + Q      +TP    P+   S     L SP         S 
Sbjct: 1315 DHPPHT----PGLCGSLAKSQSTETVPATPGGEPPLSGGSSGLS-LSSPQVPGSPF--SY 1367

Query: 1323 LVEEFWMKSAEIRRSLG----LTPV-DRSKGP--EPSFPTPAFRPVSLKSYSVEKSPQDE 1375
                  + S  + R+ G     TP      GP   P  P P  R              + 
Sbjct: 1368 PAPSPSLSSGGLPRTPGRDFSFTPTFSEPSGPLLLPVCPLPTGRRDERSGPLASPVLLET 1427

Query: 1376 GLHLLKPLSIPKRLGLPKPEGEPLSLPTPRSP-------SDRELRSAQEERRELSSSSGL 1428
            GL L  PL +P  L LP         PTP  P       S       +  R   S  S L
Sbjct: 1428 GLPLPLPLPLPLPLALPAVLRAQARAPTPLPPLLPAPLASCPPPMKRKPGRPRRSPPSML 1487

Query: 1429 GLHGSSSNMKTLGSQSFNTSDSAMLTPPSSPPPPPPPGEEPATLRRKLREAEPNASVVPP 1488
             L G         +         +L P     P  P   +P T+    R A       PP
Sbjct: 1488 SLDGPLVRPPAGAA----LGRELLLLPGQPQTPVFPSTHDPRTVTLDFRNA--GIPAPPP 1541

Query: 1489 PLPATWMRPPREPAQPPREEVRKSFVESVEEIPFADDVEDTYDDKTEDSSLQEKFFTPPS 1548
            PLP    +PP  P  PP E  +  F E   + P ++ +      + E +    +      
Sbjct: 1542 PLPP---QPPPPPPPPPVEPTKLPFKELDNQWP-SEAIPPGPRGRDEVTEEYMELAKSRG 1597

Query: 1549 CWPRPEKPRHPPLAKENG 1566
             W RP K RH  L    G
Sbjct: 1598 PWRRPPKKRHEDLVPPAG 1615



 Score = 97.1 bits (240), Expect = 2e-19
 Identities = 167/624 (26%), Positives = 227/624 (36%), Gaps = 133/624 (21%)

Query: 923  LDTGAEEDVASSSSE----SEMEEEGEEEEEE-----------------------PRLPP 955
            LD+G EED   S SE    +E EEE EEEEEE                            
Sbjct: 1029 LDSGGEEDEKESLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDESENDDEDTALSEASE 1088

Query: 956  SDLGGVPWKEAVRI-----HALLKGKSEE--ELEASKSFGPGNEEEEEEEEEYEEEEEED 1008
             D G    +E V I      A    +S E  E E+S    P + E+EEE    EEEEEE 
Sbjct: 1089 KDEGDSDEEETVSIVTSKAEATSSSESSESSEFESSSESSPSSSEDEEEVVAREEEEEE- 1147

Query: 1009 YDEEEEESSEAGNQRLQQVMHAADPLEIQADVHWTHIREREEEERMAPASESSASGAP-L 1067
              EEEE  +E       + M +A P + + D          EE  +AP       GAP +
Sbjct: 1148 --EEEEMVAE-------ESMASAGPEDFEQD---------GEEAALAP-------GAPAV 1182

Query: 1068 DENDLEEDVDSEPAEI---EGEAAEDGDPGDTGAELD-DDQHWSDSPSDADRELRLPCPA 1123
            D   +EE+VD E   +   E  +  D  P   G E   D +   + P  +     L  P 
Sbjct: 1183 DSLGMEEEVDIETEAVAPEERPSMLDEPPLPVGVEEPADSREPPEEPGLSQEGAMLLSPE 1242

Query: 1124 EGEAELELRVSEDEEKLPASPKHQERGPSQATSPIRSPQESALLFIPVHSP-----STEG 1178
                E+E R        P SP   ER P         P+   +L +P+  P         
Sbjct: 1243 PPAKEVEARP-------PLSP---ERAPEHDLEV--EPEPPMMLPLPLQPPLPPPRPPRP 1290

Query: 1179 PQLPPVPAATQEKSPEERLFPEPLLPKEKPKADAPSDLKAVHSPIRSQPVTLPEARTPVS 1238
            P  PP P  T    P   + PEPL     P         A      + P T P    P+S
Sbjct: 1291 PSPPPEPETTDASHPS--VPPEPLAEDHPPHTPGLCGSLAKSQSTETVPAT-PGGEPPLS 1347

Query: 1239 PGSPQPQPPVAASTP--PPSPLPICSQPQPSTEATVPSPTQSPIR---FQPAPAKTSTPL 1293
             GS      ++ S+P  P SP    S P PS   +     ++P R   F P  ++ S PL
Sbjct: 1348 GGS----SGLSLSSPQVPGSPF---SYPAPSPSLSSGGLPRTPGRDFSFTPTFSEPSGPL 1400

Query: 1294 ----APLPVQSQSDTKDRLGSPLAVDEALRRSDLVEEFWMKSAEIRRSLGLTPVDRSKGP 1349
                 PLP   + +    L SP+ ++  L               +   L L  V R++  
Sbjct: 1401 LLPVCPLPTGRRDERSGPLASPVLLETGLPLP--------LPLPLPLPLALPAVLRAQAR 1452

Query: 1350 EPSFPTPAFRPVSLKSYSVEKSPQDEGLHLLKPLSIPKRLGLPK---PEGEPLSLPTPRS 1406
             P+ P P   P  L S                P  + ++ G P+   P    L  P  R 
Sbjct: 1453 APT-PLPPLLPAPLASC---------------PPPMKRKPGRPRRSPPSMLSLDGPLVRP 1496

Query: 1407 PSDRELRSAQEERRELSSSSGLGLHGSSSNMKTLGSQSFNTSDSA--MLTPPSSPPPPPP 1464
            P+   L     E   L       +  S+ + +T+     N    A     PP  PPPPPP
Sbjct: 1497 PAGAAL---GRELLLLPGQPQTPVFPSTHDPRTVTLDFRNAGIPAPPPPLPPQPPPPPPP 1553

Query: 1465 PGEEPATLRRKLREAEPNASVVPP 1488
            P  EP  L  K  + +  +  +PP
Sbjct: 1554 PPVEPTKLPFKELDNQWPSEAIPP 1577



 Score = 56.2 bits (134), Expect = 3e-07
 Identities = 102/401 (25%), Positives = 138/401 (34%), Gaps = 84/401 (20%)

Query: 1161 PQESALLFIPVHSPSTEGPQLPPVPAATQEKSPEERLFPEPLLPKEKPKADAPSDLKAVH 1220
            PQ+SA      H+P     Q  P P      SP +        P E+P A A    +   
Sbjct: 372  PQDSATF---AHTPPPA--QATPAPGFKSAFSPYQTPVAHFPPPPEEPTATAAFGARDSG 426

Query: 1221 SPIRSQ-PVTLPEAR--TPVSPGSPQPQPPVAASTPPPSPLPICSQPQPSTEATVPSPTQ 1277
               R+  P  LP A       PG+P   PP     P  + + +  +P   T    P P  
Sbjct: 427  EFRRAPAPPPLPPAEPLAKEKPGTPPGPPP-----PDTNSMELGGRP---TFGWSPEPCD 478

Query: 1278 SPIRFQPAPAKTSTPLAPLPVQSQSDTKDRLGSPLAVDEA-----LRRSDLVEEFWMKSA 1332
            SP      P   S+P  P   +   D+ D     L  ++      LR  D   E  M+ +
Sbjct: 479  SP----GTPTLESSPAGP---EKPHDSLDSRIEMLLKEQRTKLLFLREPDSDTELQMEGS 531

Query: 1333 EIRRSLG----LTPVDRSKGPEPSFPTP-AFRPVSLKSYSVEKSP-----QDEGLHLLKP 1382
             I  S      L P   +  P    PTP + RP S     +  +P     +DE L L   
Sbjct: 532  PISSSSSQLSPLAPFGTNSQPGFRGPTPPSSRPSSTGLEDISPTPLPDSDEDEELDLGLG 591

Query: 1383 LSIPKRLGLPKPEG-------EPLSLPTPRSPSDRELRSAQEERRELSSSSGLGLHGSSS 1435
               P   G P P G         L L   R+P+  ++   Q+       SSG  +  S  
Sbjct: 592  PRPPPEPGPPDPAGLLSQTAEVALDLVGDRTPTSEKMDEGQQ-------SSGEDMEISDD 644

Query: 1436 NMKTLGSQSFNTSDSAMLTP------------------------PSSPPPPPPPGEEPAT 1471
             M +    S +     ++TP                        P  PPPPPPP +    
Sbjct: 645  EMPSAPITSADCPKPMVVTPGAAAVAAPSVLAPTLPLPPPPGFPPLPPPPPPPPPQPGFP 704

Query: 1472 LRRKL-------REAEPNASVVPPPLPATWMRPPREPAQPP 1505
            +   L         A P  +V PPPLPA    PP  P  PP
Sbjct: 705  MPPPLPPPPPPPPPAHPAVTVPPPPLPAPPGVPP-PPILPP 744



 Score = 41.2 bits (95), Expect = 0.010
 Identities = 59/251 (23%), Positives = 83/251 (33%), Gaps = 43/251 (17%)

Query: 1055 APASESSASGAPLDENDLEEDVDSEPAEIEGEAAEDGDPGDTGAELDDDQHWSDSPSDAD 1114
            +P S SS+  +PL         +S+P    G       P  TG E        DS  D +
Sbjct: 531  SPISSSSSQLSPL----APFGTNSQPG-FRGPTPPSSRPSSTGLEDISPTPLPDSDEDEE 585

Query: 1115 RELRLPCPAEGEAELELRVSEDEEKLPASPKHQERGPSQATSPIRSPQESALLFIPVHSP 1174
             +L L                     P  P   E GP      +    E AL  +   +P
Sbjct: 586  LDLGLG--------------------PRPPP--EPGPPDPAGLLSQTAEVALDLVGDRTP 623

Query: 1175 STEGPQLPPVPAATQEKSPEERLFPEPLLPKEKPKADAPSD-LKAVHSP---IRSQPVTL 1230
            ++E        +    +  ++ +   P+   + PK    +    AV +P     + P+  
Sbjct: 624  TSEKMDEGQQSSGEDMEISDDEMPSAPITSADCPKPMVVTPGAAAVAAPSVLAPTLPLPP 683

Query: 1231 PEARTPVSPGSPQPQPPVAASTPPPSPLPICSQPQPSTEATVPSPTQSPIRFQPAPAKTS 1290
            P    P+ P  P P P      PPP P P    P      TVP P        P PA   
Sbjct: 684  PPGFPPLPPPPPPPPPQPGFPMPPPLPPPPPPPPPAHPAVTVPPP--------PLPAPPG 735

Query: 1291 TP----LAPLP 1297
             P    L PLP
Sbjct: 736  VPPPPILPPLP 746


>gi|150378549 tangerin [Homo sapiens]
          Length = 1523

 Score =  101 bits (251), Expect = 8e-21
 Identities = 53/120 (44%), Positives = 73/120 (60%), Gaps = 6/120 (5%)

Query: 499  EMESLVNSRTTPKLTRNESVARSSKLLGWCQRQTDGYAGVNVTDLTMSWKSGLALCAIIH 558
            E   L  S+  P L     V+ S  LL WCQ  T GY GV +T+ T SW++GLA CAI+H
Sbjct: 1023 EDRRLPGSQAPPAL-----VSSSQSLLEWCQEVTTGYRGVRITNFTTSWRNGLAFCAILH 1077

Query: 559  RYRPDLIDFDSLDEQNVEKNNQLAFDIAEKELGISPIMTGKEMASVGEPDKLSMVMYLTQ 618
            R+ PD ID+ SLD  N+++NN+ AFD     LG+S ++   +M  +  PDKL ++ YL Q
Sbjct: 1078 RFYPDKIDYASLDPLNIKQNNKQAFD-GFAALGVSRLLEPADMVLLSVPDKLIVMTYLCQ 1136



 Score = 99.8 bits (247), Expect = 2e-20
 Identities = 98/383 (25%), Positives = 161/383 (42%), Gaps = 35/383 (9%)

Query: 1619 RMQQMELASGAPRPRKASSAPSQGKERRPDS-PTRPTLRGSEEPTLKHEATSEEVLSPPS 1677
            ++ Q+E   GA   R  S+ PS   +        R    G+E P    EA         +
Sbjct: 1147 QLVQLEGGGGAGTYRVGSAQPSPPDDLDAGGLAQRLRGHGAEGPQEPKEAADR------A 1200

Query: 1678 DSGGPDGSFTSSEGSSGKSKKRSSLFSPRRNKKEKKSKGEGRPPEKPSSNLLEEAAAKPK 1737
            D   P     S    +G++ K     +PR          E RP E P+  L+  A A   
Sbjct: 1201 DGAAP--GVASRNAVAGRASKDGGAEAPR----------ESRPAEVPAEGLVNGAGAPGG 1248

Query: 1738 SLWKSVFSGYKKDKKKKADDKSCPSTPSSGATVDSGKHRVLPVVRAELQLRRQLSFS-ED 1796
                    G +  +     +      P +  +    +   L + +   +LR   SFS +D
Sbjct: 1249 G-------GVRLRRPSVNGEPGSVPPPRAHGSFSHVRDADL-LKKRRSRLRNSSSFSMDD 1300

Query: 1797 SDLSSDDVLEKSSQKSRREPR----TYTEEELNAKLTRRVQKAARRQAKQEELKRLH-RA 1851
             D  +        Q     P     T  + +     +   ++      ++  L+R    +
Sbjct: 1301 PDAGAMGAAAAEGQAPDPSPAPGPPTAADSQQPPGGSSPSEEPPPSPGEEAGLQRFQDTS 1360

Query: 1852 QIIQRQLQQVEERQRRLEERGVAVEKALRG--EAGMGKKDDPKLMQEWFKLVQEKNAMVR 1909
            Q +  +LQ +E+ QR+++ R   VE  LR   E+G  K  +  L+QEWF LV +KNA++R
Sbjct: 1361 QYVCAELQALEQEQRQIDGRAAEVEMQLRSLMESGANKLQEEVLIQEWFTLVNKKNALIR 1420

Query: 1910 YESELMIFARELELEDRQSRLQQELRERMAVEDHLKTEEELSEEKQILNEMLEVVEQRDS 1969
             + +L +   E +LE R   L +ELR  +A+ED  KT  +   E+ +L E++ +V QRD 
Sbjct: 1421 RQDQLQLLMEEQDLERRFELLSRELRAMLAIEDWQKTSAQQHREQLLLEELVSLVNQRDE 1480

Query: 1970 LVALLEEQRLREREEDKDLEAAM 1992
            LV  L+ +     EED+ LE  +
Sbjct: 1481 LVRDLDHKERIALEEDERLERGL 1503



 Score = 32.3 bits (72), Expect = 4.8
 Identities = 29/104 (27%), Positives = 41/104 (39%), Gaps = 18/104 (17%)

Query: 1388 RLGLPKPEGEPLSLPTPRSPSD----RELRSAQEERRELSSSSGLGLHGSSSN-MKTLGS 1442
            RL  P   GEP S+P PR+       R+    ++ R  L +SS   +    +  M    +
Sbjct: 1252 RLRRPSVNGEPGSVPPPRAHGSFSHVRDADLLKKRRSRLRNSSSFSMDDPDAGAMGAAAA 1311

Query: 1443 QSFNTSDSAMLTPPSS-----PP--------PPPPPGEEPATLR 1473
            +      S    PP++     PP        PPP PGEE    R
Sbjct: 1312 EGQAPDPSPAPGPPTAADSQQPPGGSSPSEEPPPSPGEEAGLQR 1355


>gi|5902122 spectrin, beta, non-erythrocytic 2 [Homo sapiens]
          Length = 2390

 Score =  100 bits (250), Expect = 1e-20
 Identities = 47/108 (43%), Positives = 73/108 (67%), Gaps = 1/108 (0%)

Query: 516 ESVARSSKLLGWCQRQTDGYAGVNVTDLTMSWKSGLALCAIIHRYRPDLIDFDSLDEQNV 575
           E  +    LL WCQ +T GY  VNV + T SW+ GLA  AI+H++RPDL+DF+SL + N 
Sbjct: 174 EKKSAKDALLLWCQMKTAGYPNVNVHNFTTSWRDGLAFNAIVHKHRPDLLDFESLKKCNA 233

Query: 576 EKNNQLAFDIAEKELGISPIMTGKEMASVGEPDKLSMVMYLTQFYEMF 623
             N Q AF++AEKELG++ ++  +++ +V +PD+ S++ Y+  +Y  F
Sbjct: 234 HYNLQNAFNLAEKELGLTKLLDPEDV-NVDQPDEKSIITYVATYYHYF 280


>gi|112382252 spectrin, beta, non-erythrocytic 1 isoform 2 [Homo
           sapiens]
          Length = 2155

 Score = 98.2 bits (243), Expect = 7e-20
 Identities = 45/108 (41%), Positives = 70/108 (64%), Gaps = 1/108 (0%)

Query: 516 ESVARSSKLLGWCQRQTDGYAGVNVTDLTMSWKSGLALCAIIHRYRPDLIDFDSLDEQNV 575
           E  +    LL WCQ +T GY  VN+ + T SW+ G+A  A+IH++RPDLIDFD L + N 
Sbjct: 158 EKKSAKDALLLWCQMKTAGYPNVNIHNFTTSWRDGMAFNALIHKHRPDLIDFDKLKKSNA 217

Query: 576 EKNNQLAFDIAEKELGISPIMTGKEMASVGEPDKLSMVMYLTQFYEMF 623
             N Q AF++AE+ LG++ ++  +++ SV  PD+ S++ Y+  +Y  F
Sbjct: 218 HYNLQNAFNLAEQHLGLTKLLDPEDI-SVDHPDEKSIITYVVTYYHYF 264


>gi|112382250 spectrin, beta, non-erythrocytic 1 isoform 1 [Homo
           sapiens]
          Length = 2364

 Score = 98.2 bits (243), Expect = 7e-20
 Identities = 45/108 (41%), Positives = 70/108 (64%), Gaps = 1/108 (0%)

Query: 516 ESVARSSKLLGWCQRQTDGYAGVNVTDLTMSWKSGLALCAIIHRYRPDLIDFDSLDEQNV 575
           E  +    LL WCQ +T GY  VN+ + T SW+ G+A  A+IH++RPDLIDFD L + N 
Sbjct: 171 EKKSAKDALLLWCQMKTAGYPNVNIHNFTTSWRDGMAFNALIHKHRPDLIDFDKLKKSNA 230

Query: 576 EKNNQLAFDIAEKELGISPIMTGKEMASVGEPDKLSMVMYLTQFYEMF 623
             N Q AF++AE+ LG++ ++  +++ SV  PD+ S++ Y+  +Y  F
Sbjct: 231 HYNLQNAFNLAEQHLGLTKLLDPEDI-SVDHPDEKSIITYVVTYYHYF 277


>gi|4501893 actinin, alpha 2 [Homo sapiens]
          Length = 894

 Score = 96.7 bits (239), Expect = 2e-19
 Identities = 58/190 (30%), Positives = 98/190 (51%), Gaps = 15/190 (7%)

Query: 516 ESVARSSKLLGWCQRQTDGYAGVNVTDLTMSWKSGLALCAIIHRYRPDLIDFDSLDEQNV 575
           E  +    LL WCQR+T  Y  VN+ +   SWK GL LCA+IHR+RPDLID+  L++ + 
Sbjct: 149 EETSAKEGLLLWCQRKTAPYRNVNIQNFHTSWKDGLGLCALIHRHRPDLIDYSKLNKDDP 208

Query: 576 EKNNQLAFDIAEKELGISPIMTGKEMASVGEPDKLSMVMYLTQFYEMFKDSLPSS----- 630
             N  LA +IAEK L I  ++  +++ +  +PD+ +++ Y++ FY  F  +  +      
Sbjct: 209 IGNINLAMEIAEKHLDIPKMLDAEDIVNTPKPDERAIMTYVSCFYHAFAGAEQAETAANR 268

Query: 631 --DTLDLNAEEKAVLIASTRSPISFLSKLGQTIS--RKRSPK------DKKEKDLDGAGK 680
               L +N E + ++    R     L  + +TI     R+P+       KK +D     +
Sbjct: 269 ICKVLAVNQENERLMEEYERLASELLEWIRRTIPWLENRTPEKTMQAMQKKLEDFRDYRR 328

Query: 681 RRKTSQSEEE 690
           + K  + +E+
Sbjct: 329 KHKPPKVQEK 338


>gi|4557241 actinin, alpha 3 [Homo sapiens]
          Length = 901

 Score = 95.5 bits (236), Expect = 5e-19
 Identities = 45/108 (41%), Positives = 68/108 (62%)

Query: 516 ESVARSSKLLGWCQRQTDGYAGVNVTDLTMSWKSGLALCAIIHRYRPDLIDFDSLDEQNV 575
           E  +    LL WCQR+T  Y  VNV +   SWK GLALCA+IHR+RPDLID+  L + + 
Sbjct: 156 EETSAKEGLLLWCQRKTAPYRNVNVQNFHTSWKDGLALCALIHRHRPDLIDYAKLRKDDP 215

Query: 576 EKNNQLAFDIAEKELGISPIMTGKEMASVGEPDKLSMVMYLTQFYEMF 623
             N   AF++AEK L I  ++  +++ +  +PD+ +++ Y++ FY  F
Sbjct: 216 IGNLNTAFEVAEKYLDIPKMLDAEDIVNTPKPDEKAIMTYVSCFYHAF 263


>gi|194097352 actinin, alpha 1 isoform c [Homo sapiens]
          Length = 887

 Score = 94.7 bits (234), Expect = 8e-19
 Identities = 42/108 (38%), Positives = 65/108 (60%)

Query: 516 ESVARSSKLLGWCQRQTDGYAGVNVTDLTMSWKSGLALCAIIHRYRPDLIDFDSLDEQNV 575
           E  +    LL WCQR+T  Y  VN+ +  +SWK GL  CA+IHR+RP+LID+  L + + 
Sbjct: 142 EETSAKEGLLLWCQRKTAPYKNVNIQNFHISWKDGLGFCALIHRHRPELIDYGKLRKDDP 201

Query: 576 EKNNQLAFDIAEKELGISPIMTGKEMASVGEPDKLSMVMYLTQFYEMF 623
             N   AFD+AEK L I  ++  +++     PD+ +++ Y++ FY  F
Sbjct: 202 LTNLNTAFDVAEKYLDIPKMLDAEDIVGTARPDEKAIMTYVSSFYHAF 249


>gi|194097350 actinin, alpha 1 isoform a [Homo sapiens]
          Length = 914

 Score = 94.7 bits (234), Expect = 8e-19
 Identities = 42/108 (38%), Positives = 65/108 (60%)

Query: 516 ESVARSSKLLGWCQRQTDGYAGVNVTDLTMSWKSGLALCAIIHRYRPDLIDFDSLDEQNV 575
           E  +    LL WCQR+T  Y  VN+ +  +SWK GL  CA+IHR+RP+LID+  L + + 
Sbjct: 142 EETSAKEGLLLWCQRKTAPYKNVNIQNFHISWKDGLGFCALIHRHRPELIDYGKLRKDDP 201

Query: 576 EKNNQLAFDIAEKELGISPIMTGKEMASVGEPDKLSMVMYLTQFYEMF 623
             N   AFD+AEK L I  ++  +++     PD+ +++ Y++ FY  F
Sbjct: 202 LTNLNTAFDVAEKYLDIPKMLDAEDIVGTARPDEKAIMTYVSSFYHAF 249


>gi|4501891 actinin, alpha 1 isoform b [Homo sapiens]
          Length = 892

 Score = 94.7 bits (234), Expect = 8e-19
 Identities = 42/108 (38%), Positives = 65/108 (60%)

Query: 516 ESVARSSKLLGWCQRQTDGYAGVNVTDLTMSWKSGLALCAIIHRYRPDLIDFDSLDEQNV 575
           E  +    LL WCQR+T  Y  VN+ +  +SWK GL  CA+IHR+RP+LID+  L + + 
Sbjct: 142 EETSAKEGLLLWCQRKTAPYKNVNIQNFHISWKDGLGFCALIHRHRPELIDYGKLRKDDP 201

Query: 576 EKNNQLAFDIAEKELGISPIMTGKEMASVGEPDKLSMVMYLTQFYEMF 623
             N   AFD+AEK L I  ++  +++     PD+ +++ Y++ FY  F
Sbjct: 202 LTNLNTAFDVAEKYLDIPKMLDAEDIVGTARPDEKAIMTYVSSFYHAF 249


>gi|115430237 spectrin, beta, non-erythrocytic 4 isoform sigma1
           [Homo sapiens]
          Length = 2564

 Score = 94.4 bits (233), Expect = 1e-18
 Identities = 47/113 (41%), Positives = 71/113 (62%), Gaps = 3/113 (2%)

Query: 513 TRNESVARSSK--LLGWCQRQTDGYAGVNVTDLTMSWKSGLALCAIIHRYRPDLIDFDSL 570
           T +    RS+K  LL WCQ +T GY  VN+ + T SW+ GLA  A+IHR+RPDL+DF  L
Sbjct: 173 TEDNRETRSAKDALLLWCQMKTAGYPEVNIQNFTTSWRDGLAFNALIHRHRPDLVDFSKL 232

Query: 571 DEQNVEKNNQLAFDIAEKELGISPIMTGKEMASVGEPDKLSMVMYLTQFYEMF 623
            + N   N Q AF  AE+ LG++ ++  +++ ++  PD+ S++ Y+  FY  F
Sbjct: 233 TKSNANYNLQRAFRTAEQHLGLARLLDPEDV-NMEAPDEKSIITYVVSFYHYF 284



 Score = 34.3 bits (77), Expect = 1.3
 Identities = 61/253 (24%), Positives = 85/253 (33%), Gaps = 31/253 (12%)

Query: 1222 PIRSQPVT--LPEARTPVSPGSPQPQPPVAASTPPPSPLPICSQPQPSTEATVPSPTQSP 1279
            P R QP    LPE    V P +    P  AA TP         +P+P  + +     + P
Sbjct: 2185 PERLQPRIDRLPEIPGRVEPAALPAAPEDAAETPATPAAAEQVRPRPERQESADRAEELP 2244

Query: 1280 IRFQPAPAKTSTPLAPLPVQSQSDTKDRLGSP----LAVDEALRRSDLVEEFWMKSAEIR 1335
             R +P   ++           QS+   R   P     A  EA     L     M+    R
Sbjct: 2245 RRRRPERQES---------VDQSEEAARRRRPERQESAEHEAAHSLTLGRYEQMERRRER 2295

Query: 1336 RSLGLTPVDRSKGPEPSFPTPAFRPVSLKSYSVEKSPQDEGLHLLKPLSIPKRLGLPK-- 1393
            R   L   + S+   P          +L     +   ++ G  L    S+P+   LP   
Sbjct: 2296 RERRLERQESSEQEMPIRGDLVKGKATLADIVEQLQEKEAGPGLPAGPSLPQPRELPPGR 2355

Query: 1394 -PEGEPLSLPTPRSPSDRELRSAQEERRELSSSSGLGLHGSSSNMKTLGSQSFNTSDSAM 1452
             P G  L   TPR    R     +  RR      G G  G S   ++  +Q         
Sbjct: 2356 LPNGLELPERTPRPDRPRARDRPKPRRRPRPREGGEG--GGSRRSRSAPAQG-------- 2405

Query: 1453 LTPPSSPPPPPPP 1465
                S+P PPPPP
Sbjct: 2406 ---GSAPAPPPPP 2415


>gi|12025678 actinin, alpha 4 [Homo sapiens]
          Length = 911

 Score = 91.7 bits (226), Expect = 7e-18
 Identities = 42/108 (38%), Positives = 67/108 (62%)

Query: 516 ESVARSSKLLGWCQRQTDGYAGVNVTDLTMSWKSGLALCAIIHRYRPDLIDFDSLDEQNV 575
           E  +    LL WCQR+T  Y  VNV +  +SWK GLA  A+IHR+RP+LI++D L + + 
Sbjct: 161 EETSAKEGLLLWCQRKTAPYKNVNVQNFHISWKDGLAFNALIHRHRPELIEYDKLRKDDP 220

Query: 576 EKNNQLAFDIAEKELGISPIMTGKEMASVGEPDKLSMVMYLTQFYEMF 623
             N   AF++AEK L I  ++  +++ +   PD+ +++ Y++ FY  F
Sbjct: 221 VTNLNNAFEVAEKYLDIPKMLDAEDIVNTARPDEKAIMTYVSSFYHAF 268


>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
          Length = 904

 Score = 91.7 bits (226), Expect = 7e-18
 Identities = 194/889 (21%), Positives = 312/889 (35%), Gaps = 158/889 (17%)

Query: 971  ALLKGKSEE----ELEASKSFGPGNEEEEEEEEEYEEEEEEDYDEEEEESSEAGNQRLQQ 1026
            A L+ K EE    ++E  K      ++E++++ + EE+E      E   S      R   
Sbjct: 122  AFLELKKEEIKQRQIEQEKLASMKKQDEDKDKRDKEEKESSREKRERSRSPRRRKSRSPS 181

Query: 1027 VMHAADPLEIQADVHWTHIREREEEERMAPASES-SASGAPLDENDLEEDVDSEPAEIEG 1085
                + P+           RER+     +P   + S S +P  E         +  E+  
Sbjct: 182  PRRRSSPVR----------RERKRSHSRSPRHRTKSRSPSPAPEKK------EKTPELPE 225

Query: 1086 EAAEDGDPGDTGAELDDDQHWSDSPSDADRELRLPCPAEGEAELELRVSEDEEKLPASPK 1145
             + +  +P    A    D      P         P P   E   E    +++EK    P+
Sbjct: 226  PSVKVKEPSVQEATSTSDILKVPKPE--------PIPEPKEPSPEKNSKKEKEKEKTRPR 277

Query: 1146 HQERGPSQATSPIRSPQESALLFIPVHSPSTEGPQLPPVPAATQEKSPEERLFPEPLLPK 1205
             + R  S++ +  RSP  +           +  P+  P P   +  SP  R  P  + P 
Sbjct: 278  SRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPR--RRPSPRRRTPPRRMPP- 334

Query: 1206 EKPKADAPSDLKAVHSPIRSQPVTLPEARTPVS-PGSPQPQPPVAASTPPPSPLPICSQP 1264
                   P   +   SP+R +       R+  S  GS        + +PP  P    S P
Sbjct: 335  -------PPRHRRSRSPVRRR------RRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSP 381

Query: 1265 QPSTEATVPSPTQSPIRFQPAPAKTSTPL---APLPVQSQSDTKDRLGSPLAVDEALRRS 1321
               T    PS +    R +P+P  T  P    +P P QS    K R+             
Sbjct: 382  PRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRV------------- 428

Query: 1322 DLVEEFWMKSAEIRRSLGLTPVDRSKGPEP-SFPTPAFRPVSLKSYSVEKSPQDEGLHLL 1380
                     S    R+ G   V + KG E    P+PA +P   +   + +S +D+G  + 
Sbjct: 429  ---------SVSPGRTSG--KVTKHKGTEKRESPSPAPKP---RKVELSESEEDKGGKMA 474

Query: 1381 KPLSIPKRLGLPKPEGEPLSLPTPRSPSDRELRSAQEERRELSSSSGLGLHGSSSNMKTL 1440
               S+ +R                +S SD    S+ E+ R   S    G  G        
Sbjct: 475  AADSVQQR--------RQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPS 526

Query: 1441 GSQSFNTSDSAMLTPP-----SSPPPPPPPGEEPATLRRKLREAEPNASVVPPPLPATWM 1495
             S S +       T P      SP PPP       T RR+      + S  PPP      
Sbjct: 527  RSASPSPRKRQKETSPRGRRRRSPSPPP-------TRRRR------SPSPAPPPRRRRTP 573

Query: 1496 RPP---REPAQPPREEVRKSFVESVEEIPFADDVEDTYDDKTEDSSLQEKFFTPPSCWPR 1552
             PP   R P+ PPR         S     ++  ++  Y         + +  +PP    R
Sbjct: 574  TPPPRRRTPSPPPRR-------RSPSPRRYSPPIQRRYSPSPPP---KRRTASPPPPPKR 623

Query: 1553 PEKPRHPPLAKENGRLPALEGTLQPQKRGLPLVSAEAKELAEERMRAREKSVKSQALRDA 1612
               P  PP  + +   P       P++R  P+    +  L+ +    R+ S  S++ R+A
Sbjct: 624  RASPSPPPKRRVSHSPP-------PKQRSSPVTKRRSPSLSSKH---RKGSSPSRSTREA 673

Query: 1613 MARQLSRMQ------QMELASGAPRPRKASSAPSQGKERRPDSPTRPTLRGSEEPTLK-- 1664
             + Q ++        +    S +P P +  ++ S  + + P   TRP  R S  P  K  
Sbjct: 674  RSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKI 733

Query: 1665 HEATS------EEVLSPPSDSGGPDGSFTS--SEGSSGKSKKRSSLFSPRRNKKEKKSKG 1716
             +A S        V S  S SG P+ +     +  S  +S+  S+ +SP    K+ KS  
Sbjct: 734  KKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSP- 792

Query: 1717 EGRPPEKPSSNLLEEAAAKPKSLWKSVFSGYKKDKKKKADDK-----------SCPSTPS 1765
               P   P  N  +E   K K   K     +KKDKK K   K           +   TP+
Sbjct: 793  --TPSPSPPRNSDQEGGGKKKK--KKKDKKHKKDKKHKKHKKHKKEKAVAAAAAAAVTPA 848

Query: 1766 SGATVDSGKHRVLPVVRAELQLRRQLSFSEDSDLSSDDVLEKSSQKSRR 1814
            + A   +   +  PV   E +   +    ++ D     + EK+ +  R+
Sbjct: 849  AIAAATTTLAQEEPVAAPEPKKETESEAEDNLDDLEKHLREKALRSMRK 897



 Score = 48.9 bits (115), Expect = 5e-05
 Identities = 85/381 (22%), Positives = 134/381 (35%), Gaps = 57/381 (14%)

Query: 1498 PREPAQPPREEVRKSFVESVEEIPFADDVEDTYDDKTEDSSLQEKFFTPPSCWPRPEKPR 1557
            PR  + P R E ++S   S      +       + K +   L E     PS   +    +
Sbjct: 182  PRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELPE-----PSVKVKEPSVQ 236

Query: 1558 HPPLAKENGRLPALEGTLQPQKRGLPLVSAEAKELAEERMRAREKSVKSQALRDAMARQL 1617
                  +  ++P  E   +P++      S + KE  + R R+R +S           +  
Sbjct: 237  EATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRS-----------KSR 285

Query: 1618 SRMQQMELASGAPRPRKASSAPSQGKERRPDSPTRPTLRGSEEPTL-----KHEATSEEV 1672
            SR +    +   PR R  S + S    RRP    RP+ R    P       +H  +   V
Sbjct: 286  SRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPV 345

Query: 1673 LSPPSDSGGPDGSFTSSEGSSGKS-----KKRSSLFSPRRNKKEKKSKGEGR-------- 1719
                  S    GS +SS  S  +S      KR+S   PR+ ++   S    R        
Sbjct: 346  RRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTS-SPPRKTRRLSPSASPPRRRHRPSPP 404

Query: 1720 --PPEKPSSNLLEEAAAKPKSLWKSVFSGY---KKDKKKKADDKSCPSTPSSGATVD--- 1771
              PP K   +   + + + +    SV  G    K  K K  + +  PS       V+   
Sbjct: 405  ATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSE 464

Query: 1772 -----SGKHRVLPVVRAELQLRRQLSFSEDSDLSSDDVLEKSSQKSRREPRTYTEEELNA 1826
                  GK      V+   Q RRQ      +  SS D    SS +  R  R++ +   N 
Sbjct: 465  SEEDKGGKMAAADSVQQRRQYRRQ------NQQSSSDSGSSSSSEDERPKRSHVK---NG 515

Query: 1827 KLTRRVQKAARRQAKQEELKR 1847
            ++ RR + +  R A     KR
Sbjct: 516  EVGRRRRHSPSRSASPSPRKR 536


>gi|75750474 spectrin domain with coiled-coils 1 NSP5a3b [Homo
           sapiens]
          Length = 987

 Score = 91.3 bits (225), Expect = 9e-18
 Identities = 43/113 (38%), Positives = 67/113 (59%), Gaps = 1/113 (0%)

Query: 512 LTRNESVARSSKLLGWCQRQTDGYAGVNVTDLTMSWKSGLALCAIIHRYRPDLIDFDSLD 571
           L R    ++ + LL WCQ++T GYA +++T+ + SW  GLA CA++H Y P  I +  L+
Sbjct: 875 LAREYGGSKRNALLKWCQKKTQGYANIDITNFSSSWSDGLAFCALLHTYLPAHIPYQELN 934

Query: 572 EQNVEKNNQLAFDIAEKELGISPIMTGKEMASVGEPDKLSMVMYLTQFYEMFK 624
            Q  ++N  LAF+ AE  +GI P +   EM     PD  S++ Y+ Q Y+ F+
Sbjct: 935 SQEKKRNLLLAFEAAE-SVGIKPSLELSEMLYTDRPDWQSVMQYVAQIYKYFE 986



 Score = 40.4 bits (93), Expect = 0.018
 Identities = 106/535 (19%), Positives = 187/535 (34%), Gaps = 73/535 (13%)

Query: 1489 PLPATWMRPPREPAQPPRE-EVRKSFVESVEEIPFADDVEDTYDDKTEDSSLQEKFFTPP 1547
            P P  +    R     PRE  V  S   SV   P ++  +      + ++    K    P
Sbjct: 11   PEPGAFTTTKRTGIPAPREFSVTVSRERSVPRGP-SNPRKSVSSPTSSNTPTPTKHLRTP 69

Query: 1548 SCWPRPEKPRHPPLAKENGRLPALEGTLQPQKRGLPLVSAEAKELAEERMRAREKSVKSQ 1607
            S  P+ E         E G   ALE     Q R L L  A+AK+    R+R+  K  K +
Sbjct: 70   STKPKQEN--------EGGEKAALES----QVREL-LAEAKAKDSEINRLRSELKKYKEK 116

Query: 1608 ALRDAMARQL--SRMQQMELASGAPRPRKASSAPSQGKERRPDSPTRPTLRGSEEPT--L 1663
               +A         +    ++ G   P   +        ++  S      R  +E    L
Sbjct: 117  RTLNAEGTDALGPNVDGTSVSPGDTEPMIRALEEKNKNFQKELSDLEEENRVLKEKLIYL 176

Query: 1664 KHEATSEEVLSPPSDS------------GGPDGSFTSSEGSSGKSKKRSSLFSPRRNKKE 1711
            +H   SE   S   DS            G P G+  SS+    K     +      +   
Sbjct: 177  EHSPNSEGAASHTGDSSCPTSITQESSFGSPTGNQMSSDIDEYKKNIHGNALRTSGSSSS 236

Query: 1712 KKSKGEGRPPEKPSSNLLEEAAAKPKSLWKSVFSGYK----KDKKKKADDKSCPSTPSSG 1767
              +K    P      ++  E  ++P S   + F   K            + S  S     
Sbjct: 237  DVTKASLSPDASDFEHITAETPSRPLSSTSNPFKSSKCSTAGSSPNSVSELSLASLTEKI 296

Query: 1768 ATVDSGKHRVLPVVRAELQ-------LRRQLSFSEDSDLSSDDVLEKS--SQKSRREPRT 1818
              ++   H     ++A LQ       + ++L+   +  +    +LE S    + R E  +
Sbjct: 297  QKMEENHHSTAEELQATLQELSDQQQMVQELTAENEKLVDEKTILETSFHQHRERAEQLS 356

Query: 1819 YTEEELNAKLTRRV--QKAARRQAKQEELK----------RLHRAQIIQRQLQQVEERQR 1866
               E+L   L  RV  ++   ++ K  EL+          R  R +++  Q Q     ++
Sbjct: 357  QENEKLMNLLQERVKNEEPTTQEGKIIELEQKCTGILEQGRFEREKLLNIQQQLTCSLRK 416

Query: 1867 RLEERGVAVEKALRGEAGMGKKDDPKLMQEWFKLVQEKNAMVRYESELMIFARELELEDR 1926
              EE   A+E   R       K++ + + E+ +L +  N M+              LE+ 
Sbjct: 417  VEEENQGALEMIKR------LKEENEKLNEFLELERHNNNMMAKT-----------LEEC 459

Query: 1927 QSRLQQELRERMAVEDHLKTEEELSEEKQILNEMLEVVEQRDSLVALLEEQRLRE 1981
            +  L+    E  +++ HL+ E++ + E   + +  E  E ++ L     E+ L E
Sbjct: 460  RVTLEGLKMENGSLKSHLQGEKQKATEASAVEQTAESCEVQEMLKVARAEKDLLE 514



 Score = 32.3 bits (72), Expect = 4.8
 Identities = 63/258 (24%), Positives = 95/258 (36%), Gaps = 40/258 (15%)

Query: 1240 GSPQPQPPVAASTPPPSPLPICSQ--PQPSTEATVPSPTQSPIRF--QPAPAKTSTPLAP 1295
            G P+   P A +T   + +P   +     S E +VP    +P +    P  + T TP   
Sbjct: 6    GRPEDPEPGAFTTTKRTGIPAPREFSVTVSRERSVPRGPSNPRKSVSSPTSSNTPTPTKH 65

Query: 1296 LPVQSQSDTKDRLGSPLAVDEALRRSDLVEEFWMKSAEIRR------------------- 1336
            L   S    ++  G   A  E+  R +L+ E   K +EI R                   
Sbjct: 66   LRTPSTKPKQENEGGEKAALESQVR-ELLAEAKAKDSEINRLRSELKKYKEKRTLNAEGT 124

Query: 1337 -SLGLTPVDRSKGPEPSFPTPAFRPVSLKSYSVEKSPQDEGLHLLKPLSI-----PKRLG 1390
             +LG      S  P  + P         K++  E S  +E   +LK   I     P   G
Sbjct: 125  DALGPNVDGTSVSPGDTEPMIRALEEKNKNFQKELSDLEEENRVLKEKLIYLEHSPNSEG 184

Query: 1391 LPKPEGEPLSLPTP-------RSPSDRELRSAQEERRELSSSSGLGLHGSSSNMKTLGSQ 1443
                 G+  S PT         SP+  ++ S  +E ++    + L   GSSS+  T  S 
Sbjct: 185  AASHTGDS-SCPTSITQESSFGSPTGNQMSSDIDEYKKNIHGNALRTSGSSSSDVTKASL 243

Query: 1444 SFNTSDSAMLT--PPSSP 1459
            S + SD   +T   PS P
Sbjct: 244  SPDASDFEHITAETPSRP 261


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.129    0.367 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 88,453,955
Number of Sequences: 37866
Number of extensions: 5324370
Number of successful extensions: 101244
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 941
Number of HSP's successfully gapped in prelim test: 2564
Number of HSP's that attempted gapping in prelim test: 35286
Number of HSP's gapped (non-prelim): 33013
length of query: 2002
length of database: 18,247,518
effective HSP length: 117
effective length of query: 1885
effective length of database: 13,817,196
effective search space: 26045414460
effective search space used: 26045414460
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 70 (31.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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