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Search of human proteins with 209571521
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|209571521 cysteine rich BMP regulator 2 isoform 2 [Homo
sapiens]
(814 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|209571521 cysteine rich BMP regulator 2 isoform 2 [Homo sapiens] 1878 0.0
gi|209571519 cysteine rich BMP regulator 2 isoform 1 [Homo sapiens] 1485 0.0
gi|114431244 von Willebrand factor C and EGF domains [Homo sapiens] 253 5e-67
gi|10092639 cysteine-rich motor neuron 1 [Homo sapiens] 214 3e-55
gi|108773804 Fraser syndrome 1 [Homo sapiens] 206 9e-53
gi|37693519 BMP-binding endothelial regulator precursor protein ... 152 2e-36
gi|222352166 nel-like 1 isoform 2 precursor [Homo sapiens] 133 6e-31
gi|222352164 nel-like 1 isoform 1 precursor [Homo sapiens] 131 3e-30
gi|223029476 NEL-like protein 2 isoform d [Homo sapiens] 127 3e-29
gi|223029474 NEL-like protein 2 isoform c [Homo sapiens] 127 3e-29
gi|223029472 NEL-like protein 2 isoform b precursor [Homo sapiens] 127 3e-29
gi|223029470 NEL-like protein 2 isoform a [Homo sapiens] 127 3e-29
gi|5453766 NEL-like protein 2 isoform b precursor [Homo sapiens] 127 3e-29
gi|40353769 chordin-like 2 [Homo sapiens] 115 1e-25
gi|134031945 SCO-spondin [Homo sapiens] 114 3e-25
gi|221316563 chordin-like 1 isoform 2 precursor [Homo sapiens] 104 3e-22
gi|221316561 chordin-like 1 isoform 1 precursor [Homo sapiens] 104 4e-22
gi|34147715 chordin-like 1 isoform 3 precursor [Homo sapiens] 103 5e-22
gi|30089980 chordin [Homo sapiens] 96 1e-19
gi|38490568 keratin associated protein 10-4 [Homo sapiens] 87 8e-17
gi|148727298 keratin associated protein 10-6 [Homo sapiens] 86 1e-16
gi|55770876 notch4 preproprotein [Homo sapiens] 85 2e-16
gi|38348414 von Willebrand factor C domain containing 2 [Homo sa... 85 3e-16
gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens] 81 4e-15
gi|161019170 mucin 5AC [Homo sapiens] 80 8e-15
gi|119466532 laminin alpha 2 subunit isoform b precursor [Homo s... 80 8e-15
gi|28559088 laminin alpha 2 subunit isoform a precursor [Homo sa... 80 8e-15
gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens] 80 8e-15
gi|89191868 von Willebrand factor preproprotein [Homo sapiens] 80 1e-14
gi|122937343 platelet endothelial aggregation receptor 1 [Homo s... 79 2e-14
>gi|209571521 cysteine rich BMP regulator 2 isoform 2 [Homo sapiens]
Length = 814
Score = 1878 bits (4864), Expect = 0.0
Identities = 814/814 (100%), Positives = 814/814 (100%)
Query: 1 MAGVGAAALSLLLHLGALALAAGAEGGAVPREPPGQQTTAHSSVLAGNSQEQWHPLREWL 60
MAGVGAAALSLLLHLGALALAAGAEGGAVPREPPGQQTTAHSSVLAGNSQEQWHPLREWL
Sbjct: 1 MAGVGAAALSLLLHLGALALAAGAEGGAVPREPPGQQTTAHSSVLAGNSQEQWHPLREWL 60
Query: 61 GRLEAAVMELREQNKDLQTRVRQLESCECHPASPQCWGLGRAWPEGARWEPDACTACVCQ 120
GRLEAAVMELREQNKDLQTRVRQLESCECHPASPQCWGLGRAWPEGARWEPDACTACVCQ
Sbjct: 61 GRLEAAVMELREQNKDLQTRVRQLESCECHPASPQCWGLGRAWPEGARWEPDACTACVCQ 120
Query: 121 DGAAHCGPQAHLPHCRGCSQNGQTYGNGETFSPDACTTCRCLEGTITCNQKPCPRGPCPE 180
DGAAHCGPQAHLPHCRGCSQNGQTYGNGETFSPDACTTCRCLEGTITCNQKPCPRGPCPE
Sbjct: 121 DGAAHCGPQAHLPHCRGCSQNGQTYGNGETFSPDACTTCRCLEGTITCNQKPCPRGPCPE 180
Query: 181 PGACCPHCKPGCDYEGQLYEEGVTFLSSSNPCLQCTCLRSRVRCMALKCPPSPCPEPVLR 240
PGACCPHCKPGCDYEGQLYEEGVTFLSSSNPCLQCTCLRSRVRCMALKCPPSPCPEPVLR
Sbjct: 181 PGACCPHCKPGCDYEGQLYEEGVTFLSSSNPCLQCTCLRSRVRCMALKCPPSPCPEPVLR 240
Query: 241 PGHCCPTCQGCTEGGSHWEHGQEWTTPGDPCRICRCLEGHIQCRQRECASLCPYPARPLP 300
PGHCCPTCQGCTEGGSHWEHGQEWTTPGDPCRICRCLEGHIQCRQRECASLCPYPARPLP
Sbjct: 241 PGHCCPTCQGCTEGGSHWEHGQEWTTPGDPCRICRCLEGHIQCRQRECASLCPYPARPLP 300
Query: 301 GTCCPVCDGCFLNGREHRSGEPVGSGDPCSHCRCANGSVQCEPLPCPPVPCRHPGKIPGQ 360
GTCCPVCDGCFLNGREHRSGEPVGSGDPCSHCRCANGSVQCEPLPCPPVPCRHPGKIPGQ
Sbjct: 301 GTCCPVCDGCFLNGREHRSGEPVGSGDPCSHCRCANGSVQCEPLPCPPVPCRHPGKIPGQ 360
Query: 361 CCPVCDGCEYQGHQYQSQETFRLQERGLCVRCSCQAGEVSCEEQECPVTPCALPASGRQL 420
CCPVCDGCEYQGHQYQSQETFRLQERGLCVRCSCQAGEVSCEEQECPVTPCALPASGRQL
Sbjct: 361 CCPVCDGCEYQGHQYQSQETFRLQERGLCVRCSCQAGEVSCEEQECPVTPCALPASGRQL 420
Query: 421 CPACELDGEEFAEGVQWEPDGRPCTACVCQDGVPKCGAVLCPPAPCQHPTQPPGACCPSC 480
CPACELDGEEFAEGVQWEPDGRPCTACVCQDGVPKCGAVLCPPAPCQHPTQPPGACCPSC
Sbjct: 421 CPACELDGEEFAEGVQWEPDGRPCTACVCQDGVPKCGAVLCPPAPCQHPTQPPGACCPSC 480
Query: 481 DSCTYHSQVYANGQNFTDADSPCHACHCQDGTVTCSLVDCPPTTCARPQSGPGQCCPRCP 540
DSCTYHSQVYANGQNFTDADSPCHACHCQDGTVTCSLVDCPPTTCARPQSGPGQCCPRCP
Sbjct: 481 DSCTYHSQVYANGQNFTDADSPCHACHCQDGTVTCSLVDCPPTTCARPQSGPGQCCPRCP 540
Query: 541 DCILEEEVFVDGESFSHPRDPCQECRCQEGHAHCQPRPCPRAPCAHPLPGTCCPNDCSGC 600
DCILEEEVFVDGESFSHPRDPCQECRCQEGHAHCQPRPCPRAPCAHPLPGTCCPNDCSGC
Sbjct: 541 DCILEEEVFVDGESFSHPRDPCQECRCQEGHAHCQPRPCPRAPCAHPLPGTCCPNDCSGC 600
Query: 601 AFGGKEYPSGADFPHPSDPCRLCRCLSGNVQCLARRCVPLPCPEPVLLPGECCPQCPAAP 660
AFGGKEYPSGADFPHPSDPCRLCRCLSGNVQCLARRCVPLPCPEPVLLPGECCPQCPAAP
Sbjct: 601 AFGGKEYPSGADFPHPSDPCRLCRCLSGNVQCLARRCVPLPCPEPVLLPGECCPQCPAAP 660
Query: 661 APAGCPRPGAAHARHQEYFSPPGDPCRRCLCLDGSVSCQRLPCPPAPCAHPRQGPCCPSC 720
APAGCPRPGAAHARHQEYFSPPGDPCRRCLCLDGSVSCQRLPCPPAPCAHPRQGPCCPSC
Sbjct: 661 APAGCPRPGAAHARHQEYFSPPGDPCRRCLCLDGSVSCQRLPCPPAPCAHPRQGPCCPSC 720
Query: 721 DGCLYQGKEFASGERFPSPTAACHLCLCWEGSVSCEPKACAPALCPFPARGDCCPDCDGE 780
DGCLYQGKEFASGERFPSPTAACHLCLCWEGSVSCEPKACAPALCPFPARGDCCPDCDGE
Sbjct: 721 DGCLYQGKEFASGERFPSPTAACHLCLCWEGSVSCEPKACAPALCPFPARGDCCPDCDGE 780
Query: 781 GHGIGSCRGGMRETRGLGQNNLYCPRVDLKYLLQ 814
GHGIGSCRGGMRETRGLGQNNLYCPRVDLKYLLQ
Sbjct: 781 GHGIGSCRGGMRETRGLGQNNLYCPRVDLKYLLQ 814
>gi|209571519 cysteine rich BMP regulator 2 isoform 1 [Homo sapiens]
Length = 1503
Score = 1485 bits (3844), Expect = 0.0
Identities = 665/779 (85%), Positives = 672/779 (86%), Gaps = 61/779 (7%)
Query: 1 MAGVGAAALSLLLHLGALALAAGAEGGAVPREPPGQQTTAHSSVLAGNSQEQWHPLREWL 60
MAGVGAAALSLLLHLGALALAAGAEGGAVPREPPGQQTTAHSSVLAGNSQEQWHPLREWL
Sbjct: 1 MAGVGAAALSLLLHLGALALAAGAEGGAVPREPPGQQTTAHSSVLAGNSQEQWHPLREWL 60
Query: 61 GRLEAAVMELREQNKDLQTRVRQLESCECHPASPQCWGLGRAWPEGARWEPDACTACVCQ 120
GRLEAAVMELREQNKDLQTRVRQLESCECHPASPQCWGL
Sbjct: 61 GRLEAAVMELREQNKDLQTRVRQLESCECHPASPQCWGL--------------------- 99
Query: 121 DGAAHCGPQAHLPHCRGCSQNGQTYGNGETFSPDACTTCRCLEGTITCNQKPCPRGPCPE 180
G+ + G + PDACT C C +G C
Sbjct: 100 ---------------------GRAWPEGARWEPDACTACVCQDGAAHCG----------- 127
Query: 181 PGACCPHCKPGCDYEGQLYEEGVTFLSSSNPCLQCTCLRSRVRCMALKCPPSPCPEPVLR 240
P A PHC+ GC GQ Y G TF S + C C CL V+C C C E
Sbjct: 128 PQAHLPHCR-GCSQNGQTYGNGETF--SPDACTTCRCLTGAVQCQGPSCSELNCLESCTP 184
Query: 241 PGHCCPTCQGCTEGGSHWEHGQEWTTPGDPCRICRCLEGHIQCRQRECASLCPYPARPLP 300
PG CCP C CTEGGSHWEHGQEWTTPGDPCRICRCLEGHIQCRQRECASLCPYPARPLP
Sbjct: 185 PGECCPIC--CTEGGSHWEHGQEWTTPGDPCRICRCLEGHIQCRQRECASLCPYPARPLP 242
Query: 301 GTCCPVCDGCFLNGREHRSGEPVGSGDPCSHCRCANGSVQCEPLPCPPVPCRHPGKIPGQ 360
GTCCPVCDGCFLNGREHRSGEPVGSGDPCSHCRCANGSVQCEPLPCPPVPCRHPGKIPGQ
Sbjct: 243 GTCCPVCDGCFLNGREHRSGEPVGSGDPCSHCRCANGSVQCEPLPCPPVPCRHPGKIPGQ 302
Query: 361 CCPVCDGCEYQGHQYQSQETFRLQERGLCVRCSCQAGEVSCEEQECPVTPCALPASGRQL 420
CCPVCDGCEYQGHQYQSQETFRLQERGLCVRCSCQAGEVSCEEQECPVTPCALPASGRQL
Sbjct: 303 CCPVCDGCEYQGHQYQSQETFRLQERGLCVRCSCQAGEVSCEEQECPVTPCALPASGRQL 362
Query: 421 CPACELDGEEFAEGVQWEPDGRPCTACVCQDGVPKCGAVLCPPAPCQHPTQPPGACCPSC 480
CPACELDGEEFAEGVQWEPDGRPCTACVCQDGVPKCGAVLCPPAPCQHPTQPPGACCPSC
Sbjct: 363 CPACELDGEEFAEGVQWEPDGRPCTACVCQDGVPKCGAVLCPPAPCQHPTQPPGACCPSC 422
Query: 481 DSCTYHSQVYANGQNFTDADSPCHACHCQDGTVTCSLVDCPPTTCARPQSGPGQCCPRCP 540
DSCTYHSQVYANGQNFTDADSPCHACHCQDGTVTCSLVDCPPTTCARPQSGPGQCCPRCP
Sbjct: 423 DSCTYHSQVYANGQNFTDADSPCHACHCQDGTVTCSLVDCPPTTCARPQSGPGQCCPRCP 482
Query: 541 DCILEEEVFVDGESFSHPRDPCQECRCQEGHAHCQPRPCPRAPCAHPLPGTCCPNDCSGC 600
DCILEEEVFVDGESFSHPRDPCQECRCQEGHAHCQPRPCPRAPCAHPLPGTCCPNDCSGC
Sbjct: 483 DCILEEEVFVDGESFSHPRDPCQECRCQEGHAHCQPRPCPRAPCAHPLPGTCCPNDCSGC 542
Query: 601 AFGGKEYPSGADFPHPSDPCRLCRCLSGNVQCLARRCVPLPCPEPVLLPGECCPQCPAAP 660
AFGGKEYPSGADFPHPSDPCRLCRCLSGNVQCLARRCVPLPCPEPVLLPGECCPQC P
Sbjct: 543 AFGGKEYPSGADFPHPSDPCRLCRCLSGNVQCLARRCVPLPCPEPVLLPGECCPQC---P 599
Query: 661 APAGCPRPGAAHARHQEYFSPPGDPCRRCLCLDGSVSCQRLPCPPAPCAHPRQGPCCPSC 720
APAGCPRPGAAHARHQEYFSPPGDPCRRCLCLDGSVSCQRLPCPPAPCAHPRQGPCCPSC
Sbjct: 600 APAGCPRPGAAHARHQEYFSPPGDPCRRCLCLDGSVSCQRLPCPPAPCAHPRQGPCCPSC 659
Query: 721 DGCLYQGKEFASGERFPSPTAACHLCLCWEGSVSCEPKACAPALCPFPARGDCCPDCDG 779
DGCLYQGKEFASGERFPSPTAACHLCLCWEGSVSCEPKACAPALCPFPARGDCCPDCDG
Sbjct: 660 DGCLYQGKEFASGERFPSPTAACHLCLCWEGSVSCEPKACAPALCPFPARGDCCPDCDG 718
Score = 530 bits (1365), Expect = e-150
Identities = 292/793 (36%), Positives = 355/793 (44%), Gaps = 122/793 (15%)
Query: 94 PQCWGLGRAWPEGARWEPDA--CTACVCQDGAAHCG---------------PQAHLPHCR 136
P C G + EG +WEPD CTACVCQDG CG P A P C
Sbjct: 364 PACELDGEEFAEGVQWEPDGRPCTACVCQDGVPKCGAVLCPPAPCQHPTQPPGACCPSCD 423
Query: 137 GCSQNGQTYGNGETFSP--DACTTCRCLEGTITCNQKPCPRGPCPEP----GACCPHCKP 190
C+ + Q Y NG+ F+ C C C +GT+TC+ CP C P G CCP C P
Sbjct: 424 SCTYHSQVYANGQNFTDADSPCHACHCQDGTVTCSLVDCPPTTCARPQSGPGQCCPRC-P 482
Query: 191 GCDYEGQLYEEGVTFLSSSNPCLQCTCLRSRVRCMALKCPPSPCPEPVLRPGHCCPT-CQ 249
C E +++ +G +F +PC +C C C CP +PC P+ PG CCP C
Sbjct: 483 DCILEEEVFVDGESFSHPRDPCQECRCQEGHAHCQPRPCPRAPCAHPL--PGTCCPNDCS 540
Query: 250 GCTEGGSHWEHGQEWTTPGDPCRICRCLEGHIQCRQRECASL-CPYPARPLPGTCCPVCD 308
GC GG + G ++ P DPCR+CRCL G++QC R C L CP P LPG CCP C
Sbjct: 541 GCAFGGKEYPSGADFPHPSDPCRLCRCLSGNVQCLARRCVPLPCPEPVL-LPGECCPQCP 599
Query: 309 ---GCFLNGREHRSGEPVGS--GDPCSHCRCANGSVQCEPLPCPPVPCRHPGKIPGQCCP 363
GC G H + S GDPC C C +GSV C+ LPCPP PC HP + G CCP
Sbjct: 600 APAGCPRPGAAHARHQEYFSPPGDPCRRCLCLDGSVSCQRLPCPPAPCAHPRQ--GPCCP 657
Query: 364 VCDGCEYQGHQYQSQETFRLQERGLCVRCSCQAGEVSCEEQECPVTPCALPASGRQL--C 421
CDGC YQG ++ S E F C C C G VSCE + C C PA G C
Sbjct: 658 SCDGCLYQGKEFASGERFP-SPTAACHLCLCWEGSVSCEPKACAPALCPFPARGDCCPDC 716
Query: 422 PACELDGEEFAEGVQWEPDGRPCTACVCQDGVPKCGAVLCPPAPCQHPTQPPGACCPSCD 481
CE GE + ++ PC C C G CG C P C HP P G CCP+C
Sbjct: 717 DGCEYLGESYLSNQEFPDPREPCNLCTCLGGFVTCGRRPCEPPGCSHPLIPSGHCCPTCQ 776
Query: 482 SCTYHSQVYANGQNFTDA-DSPCHACHCQDGTVTCSLVDCPPTTCARPQSGPGQC-CPRC 539
C YH A+G+ D D C C CQ+G++ C CPP C P GP C CP C
Sbjct: 777 GCRYHGVTTASGETLPDPLDPTCSLCTCQEGSMRCQKKPCPPALCPHPSPGP--CFCPVC 834
Query: 540 PDCILEEEVFVDGESFSHPRDPCQECRCQEGHAHCQPRPCPRAPCAHPLP--GTCCPNDC 597
C+ + DGE F P C+ CRCQ G C CP PC + G+CCP C
Sbjct: 835 HSCLSQGREHQDGEEFEGPAGSCEWCRCQAGQVSCVRLQCPPLPCKLQVTERGSCCPR-C 893
Query: 598 SGCAFGGKEYPSGADFPHPSDPCRLCRCLSGNVQCLARRCVPLPCPEPVLLPGECCPQC- 656
GC G+E+P G+ + P C C C G V C +C+ C +P P +CCPQC
Sbjct: 894 RGCLAHGEEHPEGSRWVPPDSACSSCVCHEGVVTCARIQCIS-SCAQPRQGPHDCCPQCS 952
Query: 657 ----------------PAA-------------------------PAPAGCPR-----PGA 670
P A P+ GCP PG
Sbjct: 953 DCEHEGRKYEPGESFQPGADPCEVCICEPQPEGPPSLRCHRRQCPSLVGCPPSQLLPPGP 1012
Query: 671 AHA--RHQEYFS-----------PPGDPCRRCLCLDGSVSCQRLPCPPAPCA----HPRQ 713
H E S P DPC C C D + C CP C H
Sbjct: 1013 QHCCPTCAEALSNCSEGLLGSELAPPDPCYTCQCQDLTWLCIHQACPELSCPLSERHTPP 1072
Query: 714 GPCCPSC----DGCLYQGKEFASGERFPSPTAACHLCLCWEGSVSCE-----PKACAPAL 764
G CCP C C++QG+E ASGER+ T C C C G+V C+ P +C P
Sbjct: 1073 GSCCPVCRAPTQSCVHQGREVASGERWTVDT--CTSCSCMAGTVRCQSQRCSPLSCGPDK 1130
Query: 765 CPFPARGDCCPDC 777
P + G CCP C
Sbjct: 1131 APALSPGSCCPRC 1143
Score = 524 bits (1349), Expect = e-148
Identities = 276/748 (36%), Positives = 347/748 (46%), Gaps = 63/748 (8%)
Query: 88 ECHPASPQCWGLGRAWPEGARW---EPDACTACVCQDGAAHCGPQ------AHLPH---- 134
+C P C G + + E C C CQ G C Q LP
Sbjct: 302 QCCPVCDGCEYQGHQYQSQETFRLQERGLCVRCSCQAGEVSCEEQECPVTPCALPASGRQ 361
Query: 135 -CRGCSQNGQTYGNGETFSPDA--CTTCRCLEGTITCNQKPCPRGPCPEP----GACCPH 187
C C +G+ + G + PD CT C C +G C CP PC P GACCP
Sbjct: 362 LCPACELDGEEFAEGVQWEPDGRPCTACVCQDGVPKCGAVLCPPAPCQHPTQPPGACCPS 421
Query: 188 CKPGCDYEGQLYEEGVTFLSSSNPCLQCTCLRSRVRCMALKCPPSPCPEPVLRPGHCCPT 247
C C Y Q+Y G F + +PC C C V C + CPP+ C P PG CCP
Sbjct: 422 CD-SCTYHSQVYANGQNFTDADSPCHACHCQDGTVTCSLVDCPPTTCARPQSGPGQCCPR 480
Query: 248 CQGCTEGGSHWEHGQEWTTPGDPCRICRCLEGHIQCRQRECASL-CPYPARPLPGTCCPV 306
C C + G+ ++ P DPC+ CRC EGH C+ R C C A PLPGTCCP
Sbjct: 481 CPDCILEEEVFVDGESFSHPRDPCQECRCQEGHAHCQPRPCPRAPC---AHPLPGTCCPN 537
Query: 307 -CDGCFLNGREHRSGEPVGS-GDPCSHCRCANGSVQCEPLPCPPVPCRHPGKIPGQCCPV 364
C GC G+E+ SG DPC CRC +G+VQC C P+PC P +PG+CCP
Sbjct: 538 DCSGCAFGGKEYPSGADFPHPSDPCRLCRCLSGNVQCLARRCVPLPCPEPVLLPGECCPQ 597
Query: 365 CD---GCEYQGHQYQSQETFRLQERGLCVRCSCQAGEVSCEEQECPVTPCALPASGRQLC 421
C GC G + + + C RC C G VSC+ CP PCA P G C
Sbjct: 598 CPAPAGCPRPGAAHARHQEYFSPPGDPCRRCLCLDGSVSCQRLPCPPAPCAHPRQG-PCC 656
Query: 422 PACE---LDGEEFAEGVQWEPDGRPCTACVCQDGVPKCGAVLCPPAPCQHPTQPPGACCP 478
P+C+ G+EFA G ++ C C+C +G C C PA C P + G CCP
Sbjct: 657 PSCDGCLYQGKEFASGERFPSPTAACHLCLCWEGSVSCEPKACAPALCPFPAR--GDCCP 714
Query: 479 SCDSCTYHSQVYANGQNFTDADSPCHACHCQDGTVTCSLVDCPPTTCARPQSGPGQCCPR 538
CD C Y + Y + Q F D PC+ C C G VTC C P C+ P G CCP
Sbjct: 715 DCDGCEYLGESYLSNQEFPDPREPCNLCTCLGGFVTCGRRPCEPPGCSHPLIPSGHCCPT 774
Query: 539 CPDCILEEEVFVDGESFSHPRDP-CQECRCQEGHAHCQPRPCPRAPCAHPLPGTCCPNDC 597
C C GE+ P DP C C CQEG CQ +PCP A C HP PG C C
Sbjct: 775 CQGCRYHGVTTASGETLPDPLDPTCSLCTCQEGSMRCQKKPCPPALCPHPSPGPCFCPVC 834
Query: 598 SGCAFGGKEYPSGADFPHPSDPCRLCRCLSGNVQCLARRCVPLPCPEPVLLPGECCPQCP 657
C G+E+ G +F P+ C CRC +G V C+ +C PLPC V G CCP+C
Sbjct: 835 HSCLSQGREHQDGEEFEGPAGSCEWCRCQAGQVSCVRLQCPPLPCKLQVTERGSCCPRC- 893
Query: 658 AAPAPAGCPRPGAAHARHQEYFSPPGDPCRRCLCLDGSVSCQRLPCPPAPCAHPRQGP-- 715
GC G H + PP C C+C +G V+C R+ C + CA PRQGP
Sbjct: 894 -----RGCLAHGEEHPEGSRWV-PPDSACSSCVCHEGVVTCARIQC-ISSCAQPRQGPHD 946
Query: 716 CCPSCDGCLYQGKEFASGERFPSPTAACHLCLCW---EG--SVSCEPKACAPAL--CP-- 766
CCP C C ++G+++ GE F C +C+C EG S+ C + C P+L CP
Sbjct: 947 CCPQCSDCEHEGRKYEPGESFQPGADPCEVCICEPQPEGPPSLRCHRRQC-PSLVGCPPS 1005
Query: 767 ---FPARGDCCPDCDGEGHGIGSCRGGM 791
P CCP C + +C G+
Sbjct: 1006 QLLPPGPQHCCPTC---AEALSNCSEGL 1030
Score = 445 bits (1144), Expect = e-125
Identities = 243/681 (35%), Positives = 312/681 (45%), Gaps = 61/681 (8%)
Query: 88 ECHPASPQCWGLGRAWPEGARWEP--DACTACVCQDGAAHCGPQ-------AH-LP---- 133
+C P P C + +G + D C C CQ+G AHC P+ AH LP
Sbjct: 476 QCCPRCPDCILEEEVFVDGESFSHPRDPCQECRCQEGHAHCQPRPCPRAPCAHPLPGTCC 535
Query: 134 --HCRGCSQNGQTYGNGETFS--PDACTTCRCLEGTITCNQKPCPRGPCPEP----GACC 185
C GC+ G+ Y +G F D C CRCL G + C + C PCPEP G CC
Sbjct: 536 PNDCSGCAFGGKEYPSGADFPHPSDPCRLCRCLSGNVQCLARRCVPLPCPEPVLLPGECC 595
Query: 186 PHCKP--GCDYEGQLYEEGVTFLSS-SNPCLQCTCLRSRVRCMALKCPPSPCPEPVLRPG 242
P C GC G + + S +PC +C CL V C L CPP+PC P R G
Sbjct: 596 PQCPAPAGCPRPGAAHARHQEYFSPPGDPCRRCLCLDGSVSCQRLPCPPAPCAHP--RQG 653
Query: 243 HCCPTCQGCTEGGSHWEHGQEWTTPGDPCRICRCLEGHIQCRQRECA-SLCPYPARPLPG 301
CCP+C GC G + G+ + +P C +C C EG + C + CA +LCP+PAR G
Sbjct: 654 PCCPSCDGCLYQGKEFASGERFPSPTAACHLCLCWEGSVSCEPKACAPALCPFPAR---G 710
Query: 302 TCCPVCDGCFLNGREHRSGEPVGSG-DPCSHCRCANGSVQCEPLPCPPVPCRHPGKIPGQ 360
CCP CDGC G + S + +PC+ C C G V C PC P C HP G
Sbjct: 711 DCCPDCDGCEYLGESYLSNQEFPDPREPCNLCTCLGGFVTCGRRPCEPPGCSHPLIPSGH 770
Query: 361 CCPVCDGCEYQGHQYQSQETFRLQERGLCVRCSCQAGEVSCEEQECPVTPCALPASGRQL 420
CCP C GC Y G S ET C C+CQ G + C+++ CP C P+ G
Sbjct: 771 CCPTCQGCRYHGVTTASGETLPDPLDPTCSLCTCQEGSMRCQKKPCPPALCPHPSPGPCF 830
Query: 421 CPACEL---DGEEFAEGVQWEPDGRPCTACVCQDGVPKCGAVLCPPAPCQHPTQPPGACC 477
CP C G E +G ++E C C CQ G C + CPP PC+ G+CC
Sbjct: 831 CPVCHSCLSQGREHQDGEEFEGPAGSCEWCRCQAGQVSCVRLQCPPLPCKLQVTERGSCC 890
Query: 478 PSCDSCTYHSQVYANGQNFTDADSPCHACHCQDGTVTCSLVDCPPTTCARPQSGPGQCCP 537
P C C H + + G + DS C +C C +G VTC+ + C ++CA+P+ GP CCP
Sbjct: 891 PRCRGCLAHGEEHPEGSRWVPPDSACSSCVCHEGVVTCARIQCI-SSCAQPRQGPHDCCP 949
Query: 538 RCPDCILEEEVFVDGESFSHPRDPCQECRCQ---EG--HAHCQPRPCPR------APCAH 586
+C DC E + GESF DPC+ C C+ EG C R CP +
Sbjct: 950 QCSDCEHEGRKYEPGESFQPGADPCEVCICEPQPEGPPSLRCHRRQCPSLVGCPPSQLLP 1009
Query: 587 PLPGTCCPNDCSGCAFGGKEYPSGADFPHPSDPCRLCRCLSGNVQCLARRCVPLPCP--E 644
P P CCP C+ E G++ P DPC C+C C+ + C L CP E
Sbjct: 1010 PGPQHCCPT-CAEALSNCSEGLLGSELA-PPDPCYTCQCQDLTWLCIHQACPELSCPLSE 1067
Query: 645 PVLLPGECCPQCPAAPAPAGCPRPGAAHARHQEYFSPPGDPCRRCLCLDGSVSCQRLPCP 704
PG CCP C A C G A + + D C C C+ G+V CQ C
Sbjct: 1068 RHTPPGSCCPVCRAPTQ--SCVHQGREVASGERWTV---DTCTSCSCMAGTVRCQSQRCS 1122
Query: 705 PAPCAHPR-----QGPCCPSC 720
P C + G CCP C
Sbjct: 1123 PLSCGPDKAPALSPGSCCPRC 1143
Score = 139 bits (349), Expect = 1e-32
Identities = 93/292 (31%), Positives = 120/292 (41%), Gaps = 48/292 (16%)
Query: 58 EWLGRLEAAVMELREQNKDLQTRVRQLESCECHPASPQCWGLGRAWPEGARWEP--DACT 115
EW V +R Q L +++ E C P C G PEG+RW P AC+
Sbjct: 858 EWCRCQAGQVSCVRLQCPPLPCKLQVTERGSCCPRCRGCLAHGEEHPEGSRWVPPDSACS 917
Query: 116 ACVCQDGAAHC--------------GPQAHLPHCRGCSQNGQTYGNGETFSP--DACTTC 159
+CVC +G C GP P C C G+ Y GE+F P D C C
Sbjct: 918 SCVCHEGVVTCARIQCISSCAQPRQGPHDCCPQCSDCEHEGRKYEPGESFQPGADPCEVC 977
Query: 160 RC---LEG--TITCNQKPCPR-GPCPE-------PGACCPHCKPGCD--YEGQLYEEGVT 204
C EG ++ C+++ CP CP P CCP C EG L E
Sbjct: 978 ICEPQPEGPPSLRCHRRQCPSLVGCPPSQLLPPGPQHCCPTCAEALSNCSEGLLGSE--- 1034
Query: 205 FLSSSNPCLQCTCLRSRVRCMALKCPPSPCP--EPVLRPGHCCPTC----QGCTEGGSHW 258
L+ +PC C C C+ CP CP E PG CCP C Q C G
Sbjct: 1035 -LAPPDPCYTCQCQDLTWLCIHQACPELSCPLSERHTPPGSCCPVCRAPTQSCVHQGREV 1093
Query: 259 EHGQEWTTPGDPCRICRCLEGHIQCRQRECASLCPYPARP---LPGTCCPVC 307
G+ WT D C C C+ G ++C+ + C+ L P + PG+CCP C
Sbjct: 1094 ASGERWTV--DTCTSCSCMAGTVRCQSQRCSPLSCGPDKAPALSPGSCCPRC 1143
Score = 65.5 bits (158), Expect = 2e-10
Identities = 33/108 (30%), Positives = 44/108 (40%), Gaps = 28/108 (25%)
Query: 111 PDACTACVCQD-----------------GAAHCGPQAHLPHCRG----CSQNGQTYGNGE 149
PD C C CQD H P + P CR C G+ +GE
Sbjct: 1038 PDPCYTCQCQDLTWLCIHQACPELSCPLSERHTPPGSCCPVCRAPTQSCVHQGREVASGE 1097
Query: 150 TFSPDACTTCRCLEGTITCNQKPC-------PRGPCPEPGACCPHCKP 190
++ D CT+C C+ GT+ C + C + P PG+CCP C P
Sbjct: 1098 RWTVDTCTSCSCMAGTVRCQSQRCSPLSCGPDKAPALSPGSCCPRCLP 1145
>gi|114431244 von Willebrand factor C and EGF domains [Homo sapiens]
Length = 955
Score = 253 bits (646), Expect = 5e-67
Identities = 141/388 (36%), Positives = 180/388 (46%), Gaps = 46/388 (11%)
Query: 77 LQTRVRQLESCECHPASPQ-------CWGLGRAWPEGARWEPDACTACVCQDGAAHC--- 126
LQ V S P SP+ CW LG +RW C+ C C+DG C
Sbjct: 360 LQGEVMGTPSSPRGPESPRLAAGPSPCWHLGAMHESRSRWTEPGCSQCWCEDGKVTCEKV 419
Query: 127 ---GPQAH---------LPHCRGCSQNGQTYGNGETFSP--DACTTCRCLEGTITCNQKP 172
+H P C GC +G G+ FSP + CT C CL G ++C
Sbjct: 420 RCEAACSHPIPSRDGGCCPSCTGCFHSGVVRAEGDVFSPPNENCTVCVCLAGNVSCISPE 479
Query: 173 CPRGPCPEPGA--CCPHCKPGCDYEGQLYEEGVTFLSSSNPCLQCTCLRSRVRCMALKCP 230
CP GPC P CC C + G+ Y +G F + C C C V C + CP
Sbjct: 480 CPSGPCQTPPQTDCCTCVPVRCYFHGRWYADGAVFSGGGDECTTCVCQNGEVECSFMPCP 539
Query: 231 PSPCP--EPVLRPGHCCPTCQ------GCT--EGGSHWEHGQEWTTPGDPCRICRC-LEG 279
CP E L PG CC TCQ GC+ + G + GQ W +PGDPC +C C +G
Sbjct: 540 ELACPREEWRLGPGQCCFTCQEPTPSTGCSLDDNGVEFPIGQIW-SPGDPCELCICQADG 598
Query: 280 HIQCRQRECASLCPYPARPLPGTCCPVCD-GCFLNGREHRSGEPVGSG-DPCSHCRCANG 337
+ C++ +C CP+P R +PG CCP C GC GR + E S DPC C C G
Sbjct: 599 SVSCKRTDCVDSCPHPIR-IPGQCCPDCSAGCTYTGRIFYNNETFPSVLDPCLSCICLLG 657
Query: 338 SVQCEPLPCPPVPCRHPGKIPGQCCPVCDGCEYQGHQYQSQETFRLQERGLCVRCSCQAG 397
SV C P+ C P+ C +P G+CCPVC C Y+G + + + F L + C RC+CQ G
Sbjct: 658 SVACSPVDC-PITCTYPFHPDGECCPVCRDCNYEGRKVANGQVFTLDDEP-CTRCTCQLG 715
Query: 398 EVSCEEQECP---VTPCALPASGRQLCP 422
EVSCE+ C P LP CP
Sbjct: 716 EVSCEKVPCQRACADPALLPGDCCSSCP 743
Score = 230 bits (587), Expect = 3e-60
Identities = 137/363 (37%), Positives = 166/363 (45%), Gaps = 39/363 (10%)
Query: 436 QWEPDGRPCTACVCQDGVPKCGAVLCPPAPCQHPTQP-PGACCPSCDSCTYHSQVYANGQ 494
+W G C+ C C+DG C V C A C HP G CCPSC C + V A G
Sbjct: 398 RWTEPG--CSQCWCEDGKVTCEKVRCEAA-CSHPIPSRDGGCCPSCTGCFHSGVVRAEGD 454
Query: 495 NFTDADSPCHACHCQDGTVTCSLVDCPPTTCARPQSGPGQCCPRCP-DCILEEEVFVDGE 553
F+ + C C C G V+C +CP C P CC P C + DG
Sbjct: 455 VFSPPNENCTVCVCLAGNVSCISPECPSGPCQTPPQT--DCCTCVPVRCYFHGRWYADGA 512
Query: 554 SFSHPRDPCQECRCQEGHAHCQPRPCPRAPCAHPL----PGTCC-----PNDCSGCAF-- 602
FS D C C CQ G C PCP C PG CC P +GC+
Sbjct: 513 VFSGGGDECTTCVCQNGEVECSFMPCPELACPREEWRLGPGQCCFTCQEPTPSTGCSLDD 572
Query: 603 GGKEYPSGADFPHPSDPCRLCRCLS-GNVQCLARRCVPLPCPEPVLLPGECCPQCPAAPA 661
G E+P G + P DPC LC C + G+V C CV CP P+ +PG+CCP C A
Sbjct: 573 NGVEFPIGQIWS-PGDPCELCICQADGSVSCKRTDCVD-SCPHPIRIPGQCCPDCSA--- 627
Query: 662 PAGCPRPGAAHARHQEYFSPPGDPCRRCLCLDGSVSCQRLPCPPAPCAHP--RQGPCCPS 719
GC G + E F DPC C+CL GSV+C + CP C +P G CCP
Sbjct: 628 --GCTYTGRIFYNN-ETFPSVLDPCLSCICLLGSVACSPVDCP-ITCTYPFHPDGECCPV 683
Query: 720 CDGCLYQGKEFASGERFPSPTAACHLCLCWEGSVSCE----PKACA-PALCPFPARGDCC 774
C C Y+G++ A+G+ F C C C G VSCE +ACA PAL P GDCC
Sbjct: 684 CRDCNYEGRKVANGQVFTLDDEPCTRCTCQLGEVSCEKVPCQRACADPALLP----GDCC 739
Query: 775 PDC 777
C
Sbjct: 740 SSC 742
Score = 229 bits (585), Expect = 6e-60
Identities = 134/365 (36%), Positives = 165/365 (45%), Gaps = 33/365 (9%)
Query: 251 CTEGGSHWEHGQEWTTPGDPCRICRCLEGHIQCRQRECASLCPYPARPLPGTCCPVCDGC 310
C G+ E WT PG C C C +G + C + C + C +P G CCP C GC
Sbjct: 386 CWHLGAMHESRSRWTEPG--CSQCWCEDGKVTCEKVRCEAACSHPIPSRDGGCCPSCTGC 443
Query: 311 FLNGREHRSGEPVGS-GDPCSHCRCANGSVQCEPLPCPPVPCRHPGKIPGQCCP-VCDGC 368
F +G G+ + C+ C C G+V C CP PC+ P + CC V C
Sbjct: 444 FHSGVVRAEGDVFSPPNENCTVCVCLAGNVSCISPECPSGPCQTPPQT--DCCTCVPVRC 501
Query: 369 EYQGHQYQSQETFRLQERGLCVRCSCQAGEVSCEEQECPVTPCALPASGRQLCPA----- 423
+ G Y F C C CQ GEV C CP C P +L P
Sbjct: 502 YFHGRWYADGAVFS-GGGDECTTCVCQNGEVECSFMPCPELAC--PREEWRLGPGQCCFT 558
Query: 424 ---------CELD--GEEFAEGVQWEPDGRPCTACVCQ-DGVPKCGAVLCPPAPCQHPTQ 471
C LD G EF G W P G PC C+CQ DG C C + C HP +
Sbjct: 559 CQEPTPSTGCSLDDNGVEFPIGQIWSP-GDPCELCICQADGSVSCKRTDCVDS-CPHPIR 616
Query: 472 PPGACCPSCDS-CTYHSQVYANGQNFTDADSPCHACHCQDGTVTCSLVDCPPTTCARPQS 530
PG CCP C + CTY +++ N + F PC +C C G+V CS VDCP TC P
Sbjct: 617 IPGQCCPDCSAGCTYTGRIFYNNETFPSVLDPCLSCICLLGSVACSPVDCP-ITCTYPFH 675
Query: 531 GPGQCCPRCPDCILEEEVFVDGESFSHPRDPCQECRCQEGHAHCQPRPCPRAPCAHP--L 588
G+CCP C DC E +G+ F+ +PC C CQ G C+ PC RA CA P L
Sbjct: 676 PDGECCPVCRDCNYEGRKVANGQVFTLDDEPCTRCTCQLGEVSCEKVPCQRA-CADPALL 734
Query: 589 PGTCC 593
PG CC
Sbjct: 735 PGDCC 739
Score = 218 bits (555), Expect = 2e-56
Identities = 139/393 (35%), Positives = 177/393 (45%), Gaps = 30/393 (7%)
Query: 174 PRGPCPEPGACCPHCKPGCDYEGQLYEEGVTFLSSSNPCLQCTCLRSRVRCMALKCPPSP 233
PRGP A P C + G ++E + C QC C +V C ++C +
Sbjct: 371 PRGPESPRLAAGPS---PCWHLGAMHESRSRWTEPG--CSQCWCEDGKVTCEKVRCEAA- 424
Query: 234 CPEPV-LRPGHCCPTCQGCTEGGSHWEHGQEWTTPGDPCRICRCLEGHIQCRQRECAS-L 291
C P+ R G CCP+C GC G G ++ P + C +C CL G++ C EC S
Sbjct: 425 CSHPIPSRDGGCCPSCTGCFHSGVVRAEGDVFSPPNENCTVCVCLAGNVSCISPECPSGP 484
Query: 292 CPYPARPLPGTCCPVCDGCFLNGREHRSGEPV-GSGDPCSHCRCANGSVQCEPLPCPPVP 350
C P + TC PV C+ +GR + G G GD C+ C C NG V+C +PCP +
Sbjct: 485 CQTPPQTDCCTCVPV--RCYFHGRWYADGAVFSGGGDECTTCVCQNGEVECSFMPCPELA 542
Query: 351 C-RHPGKI-PGQCCPVCD------GCEYQGHQYQSQETFRLQERGLCVRCSCQA-GEVSC 401
C R ++ PGQCC C GC + + C C CQA G VSC
Sbjct: 543 CPREEWRLGPGQCCFTCQEPTPSTGCSLDDNGVEFPIGQIWSPGDPCELCICQADGSVSC 602
Query: 402 EEQECPVTPCALPAS-GRQLCP----ACELDGEEFAEGVQWEPDGRPCTACVCQDGVPKC 456
+ +C V C P Q CP C G F + PC +C+C G C
Sbjct: 603 KRTDC-VDSCPHPIRIPGQCCPDCSAGCTYTGRIFYNNETFPSVLDPCLSCICLLGSVAC 661
Query: 457 GAVLCPPAPCQHPTQPPGACCPSCDSCTYHSQVYANGQNFTDADSPCHACHCQDGTVTCS 516
V CP C +P P G CCP C C Y + ANGQ FT D PC C CQ G V+C
Sbjct: 662 SPVDCP-ITCTYPFHPDGECCPVCRDCNYEGRKVANGQVFTLDDEPCTRCTCQLGEVSCE 720
Query: 517 LVDCPPTTCARPQSGPGQCCPRCPDCI--LEEE 547
V C CA P PG CC CPD + LEE+
Sbjct: 721 KVPC-QRACADPALLPGDCCSSCPDSLSPLEEK 752
Score = 216 bits (550), Expect = 7e-56
Identities = 139/404 (34%), Positives = 172/404 (42%), Gaps = 37/404 (9%)
Query: 329 CSHCRCANGSVQCEPLPCPPVPCRHPGKIP---GQCCPVCDGCEYQGHQYQSQETFRLQE 385
CS C C +G V CE + C C HP IP G CCP C GC + G + F
Sbjct: 404 CSQCWCEDGKVTCEKVRCEAA-CSHP--IPSRDGGCCPSCTGCFHSGVVRAEGDVFSPPN 460
Query: 386 RGLCVRCSCQAGEVSCEEQECPVTPCALPASGRQLCPA----CELDGEEFAEGVQWEPDG 441
C C C AG VSC ECP PC P C C G +A+G + G
Sbjct: 461 EN-CTVCVCLAGNVSCISPECPSGPCQTPPQ-TDCCTCVPVRCYFHGRWYADGAVFSGGG 518
Query: 442 RPCTACVCQDGVPKCGAVLCPPAPCQHPTQP--PGACCPSCDSCTYHSQV--------YA 491
CT CVCQ+G +C + CP C PG CC +C T + +
Sbjct: 519 DECTTCVCQNGEVECSFMPCPELACPREEWRLGPGQCCFTCQEPTPSTGCSLDDNGVEFP 578
Query: 492 NGQNFTDADSPCHACHCQ-DGTVTCSLVDCPPTTCARPQSGPGQCCPRCP-DCILEEEVF 549
GQ ++ D PC C CQ DG+V+C DC + C P PGQCCP C C +F
Sbjct: 579 IGQIWSPGD-PCELCICQADGSVSCKRTDCVDS-CPHPIRIPGQCCPDCSAGCTYTGRIF 636
Query: 550 VDGESFSHPRDPCQECRCQEGHAHCQPRPCPRAPCAHPL--PGTCCPNDCSGCAFGGKEY 607
+ E+F DPC C C G C P CP C +P G CCP C C + G++
Sbjct: 637 YNNETFPSVLDPCLSCICLLGSVACSPVDCP-ITCTYPFHPDGECCPV-CRDCNYEGRKV 694
Query: 608 PSGADFPHPSDPCRLCRCLSGNVQCLARRCVPLPCPEPVLLPGECCPQCPAAPAPAGCPR 667
+G F +PC C C G V C C C +P LLPG+CC CP + +P +
Sbjct: 695 ANGQVFTLDDEPCTRCTCQLGEVSCEKVPC-QRACADPALLPGDCCSSCPDSLSPLEEKQ 753
Query: 668 PGAAHARHQEYFSPPGDPCRRCLCLDGSVSCQRLPCPPAPCAHP 711
+ H FS G R L D CP P A P
Sbjct: 754 GLSPHG--NVAFSKAG----RSLHGDTEAPVNCSSCPGPPTASP 791
Score = 213 bits (543), Expect = 4e-55
Identities = 198/690 (28%), Positives = 261/690 (37%), Gaps = 80/690 (11%)
Query: 122 GAAHCGPQAHLPHCR-GCSQNGQTYGNGETFSPDACTTCRCLEGTITCNQKPCPRGPCPE 180
G HC LP C GC G+G +P+ C+ C+ E TC P GPC E
Sbjct: 62 GGGHCT----LPLCSFGC-------GSGICIAPNVCS-CQDGEQGATC---PETHGPCGE 106
Query: 181 PGACCPHCKPGCDYEGQLYEEGVTFLSSSNPCLQCTCLRSRVRCMAL-KCPPSPCPEPVL 239
G GC ++ G + ++ +RC + +C S C
Sbjct: 107 YGCDLTCNHGGCQEVARVCPVGFSMTETA----------VGIRCTDIDECVTSSCE---- 152
Query: 240 RPGHCCPTCQGCTEGGSHWEHGQEWTTPGDPCRICRCLEGHIQCRQRECASLCPYPARPL 299
GHC T EGG E G D C+ + +C C C +
Sbjct: 153 --GHCVNT-----EGGFVCECGPGMQLSADR-HSCQDTD---ECLGTPCQQRCK---NSI 198
Query: 300 PGTCCPVCDGCFLNGREHRSGEPVGSGDP-----CSH-CRCANGSVQCEPLPCPPVPCRH 353
C G L+G H + P C H C GS C C P
Sbjct: 199 GSYKCSCRTGFHLHGNRHSCVDVNECRRPLERRVCHHSCHNTVGSFLCT---CRPGFRLR 255
Query: 354 PGKIPGQCCP---VCDGCEYQGHQYQSQETFRLQERGLCVRCSCQAGEVSCEEQECPVTP 410
++ + P + Q Q+ S+ L E G + V
Sbjct: 256 ADRVSCEAFPKAVLAPSAILQPRQHPSKMLLLLPEAGRPALSPGHSPPSGAPGPPAGVRT 315
Query: 411 CALPASGRQLCPACELDGEEFAEGVQWEPDGRPCTACVCQDGVPKC--GAVLCPPAPCQH 468
LP+ +L + + P P + + P G V+ P+ +
Sbjct: 316 TRLPSPTPRLPTSSPSAPVWLLSTLLATPV--PTASLLGNLRPPSLLQGEVMGTPSSPRG 373
Query: 469 PTQPPGACCPSCDSCTYHSQVYANGQNFTDADSPCHACHCQDGTVTCSLVDCPPTTCARP 528
P P A PS C + ++ + +T+ C C C+DG VTC V C C+ P
Sbjct: 374 PESPRLAAGPS--PCWHLGAMHESRSRWTEPG--CSQCWCEDGKVTCEKVRC-EAACSHP 428
Query: 529 -QSGPGQCCPRCPDCILEEEVFVDGESFSHPRDPCQECRCQEGHAHCQPRPCPRAPCAHP 587
S G CCP C C V +G+ FS P + C C C G+ C CP PC P
Sbjct: 429 IPSRDGGCCPSCTGCFHSGVVRAEGDVFSPPNENCTVCVCLAGNVSCISPECPSGPCQTP 488
Query: 588 LPGTCCPNDCSGCAFGGKEYPSGADFPHPSDPCRLCRCLSGNVQCLARRCVPLPCP--EP 645
CC C F G+ Y GA F D C C C +G V+C C L CP E
Sbjct: 489 PQTDCCTCVPVRCYFHGRWYADGAVFSGGGDECTTCVCQNGEVECSFMPCPELACPREEW 548
Query: 646 VLLPGECCPQCPAAPAPAGCPRPGAAHARHQEYFSPPGDPCRRCLC-LDGSVSCQRLPCP 704
L PG+CC C GC PGDPC C+C DGSVSC+R C
Sbjct: 549 RLGPGQCCFTCQEPTPSTGCSLDDNGVEFPIGQIWSPGDPCELCICQADGSVSCKRTDCV 608
Query: 705 PAPCAHPRQ--GPCCPSCD-GCLYQGKEFASGERFPSPTAACHLCLCWEGSVSCEPKACA 761
+ C HP + G CCP C GC Y G+ F + E FPS C C+C GSV+C P C
Sbjct: 609 DS-CPHPIRIPGQCCPDCSAGCTYTGRIFYNNETFPSVLDPCLSCICLLGSVACSPVDC- 666
Query: 762 PALC--PFPARGDCCP---DCDGEGHGIGS 786
P C PF G+CCP DC+ EG + +
Sbjct: 667 PITCTYPFHPDGECCPVCRDCNYEGRKVAN 696
Score = 155 bits (393), Expect = 1e-37
Identities = 99/303 (32%), Positives = 131/303 (43%), Gaps = 42/303 (13%)
Query: 83 QLESCECHPASPQCWGLGRAWPEGARWEP--DACTACVCQDGAAHCG----PQAHLPH-- 134
Q + C C P +C+ GR + +GA + D CT CVCQ+G C P+ P
Sbjct: 490 QTDCCTCVPV--RCYFHGRWYADGAVFSGGGDECTTCVCQNGEVECSFMPCPELACPREE 547
Query: 135 -----------CR------GCS--QNGQTYGNGETFSP-DACTTCRC-LEGTITCNQKPC 173
C+ GCS NG + G+ +SP D C C C +G+++C + C
Sbjct: 548 WRLGPGQCCFTCQEPTPSTGCSLDDNGVEFPIGQIWSPGDPCELCICQADGSVSCKRTDC 607
Query: 174 PRGPCPEP----GACCPHCKPGCDYEGQLYEEGVTFLSSSNPCLQCTCLRSRVRCMALKC 229
CP P G CCP C GC Y G+++ TF S +PCL C CL V C + C
Sbjct: 608 VDS-CPHPIRIPGQCCPDCSAGCTYTGRIFYNNETFPSVLDPCLSCICLLGSVACSPVDC 666
Query: 230 PPSPCPEPVLRPGHCCPTCQGCTEGGSHWEHGQEWTTPGDPCRICRCLEGHIQCRQRECA 289
P + C P G CCP C+ C G +GQ +T +PC C C G + C + C
Sbjct: 667 PIT-CTYPFHPDGECCPVCRDCNYEGRKVANGQVFTLDDEPCTRCTCQLGEVSCEKVPCQ 725
Query: 290 SLCPYPARPLPGTCCPVCDGCFLNGREHRSGEPVGSGDPCSHCRCANGS----VQCEPLP 345
C PA LPG CC C E + P G+ R +G V C P
Sbjct: 726 RACADPAL-LPGDCCSSCPDSLSPLEEKQGLSPHGNVAFSKAGRSLHGDTEAPVNCSSCP 784
Query: 346 CPP 348
PP
Sbjct: 785 GPP 787
>gi|10092639 cysteine-rich motor neuron 1 [Homo sapiens]
Length = 1036
Score = 214 bits (544), Expect = 3e-55
Identities = 171/630 (27%), Positives = 222/630 (35%), Gaps = 123/630 (19%)
Query: 144 TYGNGETFSPDACTT----CRCLEGTITCNQKPCPRGPCPE--------PGACCP----- 186
+Y + D C T C CL G C C G P PG CC
Sbjct: 272 SYETQVRLTADGCCTLPTRCECLSGL--CGFPVCEVGSTPRIVSRGDGTPGKCCDVFECV 329
Query: 187 -HCKPGCDYEGQLYEEGVTFLSSSNPCLQCTCLRSRVRCMALKCPPSPCPEPVLRPGHCC 245
KP C + Y +G F + C C C C +C C + G CC
Sbjct: 330 NDTKPACVFNNVEYYDGDMFRMDN--CRFCRCQGGVAICFTAQCGEINCERYYVPEGECC 387
Query: 246 PTCQ----------GCTEGGSHWEHGQEWTTPGDPCRICRCLEGHIQCRQRECASLCPYP 295
P C+ GC G HG W D C C+C+ G C C C P
Sbjct: 388 PVCEDPVYPFNNPAGCYANGLILAHGDRWRE--DDCTFCQCVNGERHCVATVCGQTCTNP 445
Query: 296 ARPLPGTCCPVCD----------------GCFLNGREHRSGEPVGSGDPCSHCRCANGSV 339
+ +PG CCPVC+ C L G++ +G + C C+C N
Sbjct: 446 VK-VPGECCPVCEEPTIITVDPPACGELSNCTLTGKDCINGFK-RDHNGCRTCQCINTEE 503
Query: 340 QC-EPLPCPPVPCRHPGKIPGQCCPVCDGCEYQGHQYQSQETFRLQERGL------CVRC 392
C E + C Q C +C+ C + + + + GL C C
Sbjct: 504 LCSERKQGCTLNCPFGFLTDAQNCEICE-CRPRPKKCRPIICDKYCPLGLLKNKHGCDIC 562
Query: 393 SCQ-AGEVSC----------EEQECPVTPC---ALPASGRQLCPAC-ELDGEEFAEGVQW 437
C+ E+SC + C + C + A L C +DG W
Sbjct: 563 RCKKCPELSCSKICPLGFQQDSHGCLICKCREASASAGPPILSGTCLTVDGHHHKNEESW 622
Query: 438 EPDGRPCTACVCQDGVPKCGAVLCPPAPCQHPTQPPGACCPSC--------DSCTYHSQV 489
DG C C C +G C + CP C +PT PG CCPSC + S
Sbjct: 623 H-DG--CRECYCLNGREMCALITCPVPACGNPTIHPGQCCPSCADDFVVQKPELSTPSIC 679
Query: 490 YA-NGQNFTDADS----PCHACHCQDGTVTCSLVDCPPTTCARPQSGPGQCCPRCPD--- 541
+A G+ F + ++ C C C G V C CPP C P CCP+C D
Sbjct: 680 HAPGGEYFVEGETWNIDSCTQCTCHSGRVLCETEVCPPLLCQNPSRTQDSCCPQCTDQPF 739
Query: 542 -------------CILEE-EVFVDGESFSHPRDPCQECRCQEGHAHCQPRPCPRAPCAHP 587
C +E ++F+ ES+ D C C C + C CP C P
Sbjct: 740 RPSLSRNNSVPNYCKNDEGDIFLAAESWKP--DVCTSCICIDSVISCFSESCPSVSCERP 797
Query: 588 L--PGTCCPNDCSG-------CAFGGKEYPSGADFPHPSDPCRLCRCLSGNVQCLARRCV 638
+ G CCP C F GK Y + D C C CL G C C
Sbjct: 798 VLRKGQCCPYCIEDTIPKKVVCHFSGKAYADEERWD--LDSCTHCYCLQGQTLCSTVSCP 855
Query: 639 PLPCPEPVLLPGECCPQCPA--APAPAGCP 666
PLPC EP+ + G CCP CP P P P
Sbjct: 856 PLPCVEPINVEGSCCPMCPEMYVPEPTNIP 885
Score = 204 bits (520), Expect = 2e-52
Identities = 154/569 (27%), Positives = 205/569 (36%), Gaps = 162/569 (28%)
Query: 138 CSQNGQTYGNGETFSPDACTTCRCLEG-----TITCNQKPCPRGPCPEPGACCPHCKP-- 190
C N Y +G+ F D C CRC G T C + C R PE G CCP C+
Sbjct: 336 CVFNNVEYYDGDMFRMDNCRFCRCQGGVAICFTAQCGEINCERYYVPE-GECCPVCEDPV 394
Query: 191 -------GCDYEGQLYEEGVTFLSSSNPCLQCTCLRSRVRCMALKCPPSPCPEPVLRPGH 243
GC G + G + + C C C+ C+A C + C PV PG
Sbjct: 395 YPFNNPAGCYANGLILAHGDRW--REDDCTFCQCVNGERHCVATVCGQT-CTNPVKVPGE 451
Query: 244 CCPTCQ----------------GCTEGGSHWEHGQEWTTPGDPCRICRCLEGHIQCRQRE 287
CCP C+ CT G +G + G CR C+C+ C +R+
Sbjct: 452 CCPVCEEPTIITVDPPACGELSNCTLTGKDCINGFKRDHNG--CRTCQCINTEELCSERK 509
Query: 288 --CASLCPY------------PARPLPGTCCPV----------------CD--------- 308
C CP+ RP P C P+ CD
Sbjct: 510 QGCTLNCPFGFLTDAQNCEICECRPRPKKCRPIICDKYCPLGLLKNKHGCDICRCKKCPE 569
Query: 309 ----------------GCFLNGREHRS---GEPVGSG-----------------DPCSHC 332
GC + S G P+ SG D C C
Sbjct: 570 LSCSKICPLGFQQDSHGCLICKCREASASAGPPILSGTCLTVDGHHHKNEESWHDGCREC 629
Query: 333 RCANGSVQCEPLPCPPVPCRHPGKIPGQCCPVCDG--------------CEYQGHQYQSQ 378
C NG C + CP C +P PGQCCP C C G +Y +
Sbjct: 630 YCLNGREMCALITCPVPACGNPTIHPGQCCPSCADDFVVQKPELSTPSICHAPGGEYFVE 689
Query: 379 -ETFRLQERGLCVRCSCQAGEVSCEEQECPVTPCALPASGRQ-LCPAC------------ 424
ET+ + C +C+C +G V CE + CP C P+ + CP C
Sbjct: 690 GETWNIDS---CTQCTCHSGRVLCETEVCPPLLCQNPSRTQDSCCPQCTDQPFRPSLSRN 746
Query: 425 --------ELDGEEFAEGVQWEPDGRPCTACVCQDGVPKCGAVLCPPAPCQHPTQPPGAC 476
+G+ F W+PD CT+C+C D V C + CP C+ P G C
Sbjct: 747 NSVPNYCKNDEGDIFLAAESWKPD--VCTSCICIDSVISCFSESCPSVSCERPVLRKGQC 804
Query: 477 CPSCDS--------CTYHSQVYANGQNFTDADSPCHACHCQDGTVTCSLVDCPPTTCARP 528
CP C C + + YA+ + + D DS C C+C G CS V CPP C P
Sbjct: 805 CPYCIEDTIPKKVVCHFSGKAYADEERW-DLDS-CTHCYCLQGQTLCSTVSCPPLPCVEP 862
Query: 529 QSGPGQCCPRCPDCILEEEVFVDGESFSH 557
+ G CCP CP+ + E + E +H
Sbjct: 863 INVEGSCCPMCPEMYVPEPTNIPIEKTNH 891
Score = 182 bits (462), Expect = 1e-45
Identities = 185/732 (25%), Positives = 244/732 (33%), Gaps = 207/732 (28%)
Query: 220 SRVRC---MALKCPP-SPCPEPVLRPGHCCP-----TCQG-------CTEGGSHWEHGQE 263
S+ RC + +CP S E PG CCP C C G + +
Sbjct: 175 SKARCEVQFSPRCPEDSVLIEGYAPPGECCPLPSRCVCNPAGCLRKVCQPGNLNILVSKA 234
Query: 264 WTTPGDPCRICRCLEGH-IQCRQRECASLCPYPARPLPGTCCPVCDGCFLNGREHRSGEP 322
PG+ C + C + CR EC P+ T CP + +
Sbjct: 235 SGKPGECCDLYECKPVFGVDCRTVECP--------PVQQTACPP---------DSYETQV 277
Query: 323 VGSGDPC----SHCRCANGSVQ---CEPLPCPPVPCRHPGKIPGQCCPVCD-------GC 368
+ D C + C C +G CE P + R G PG+CC V + C
Sbjct: 278 RLTADGCCTLPTRCECLSGLCGFPVCEVGSTPRIVSRGDGT-PGKCCDVFECVNDTKPAC 336
Query: 369 EYQGHQYQSQETFRLQERGLCVRCSCQAGEVSCEEQECPVTPCA---LPASGRQLCPACE 425
+ +Y + FR+ C C CQ G C +C C +P + CP CE
Sbjct: 337 VFNNVEYYDGDMFRMDN---CRFCRCQGGVAICFTAQCGEINCERYYVPEG--ECCPVCE 391
Query: 426 -------------LDGEEFAEGVQWEPDGRPCTACVCQDGVPKCGAVLCPPAPCQHPTQP 472
+G A G +W D CT C C +G C A +C C +P +
Sbjct: 392 DPVYPFNNPAGCYANGLILAHGDRWREDD--CTFCQCVNGERHCVATVCGQT-CTNPVKV 448
Query: 473 PGACCPSCD----------------SCTYHSQVYANGQN--------------------- 495
PG CCP C+ +CT + NG
Sbjct: 449 PGECCPVCEEPTIITVDPPACGELSNCTLTGKDCINGFKRDHNGCRTCQCINTEELCSER 508
Query: 496 ------------FTDADSPCHACHCQDGTVTCSLVDCP---PTTCARPQSGPGQC-CPRC 539
TDA + C C C+ C + C P + + G C C +C
Sbjct: 509 KQGCTLNCPFGFLTDAQN-CEICECRPRPKKCRPIICDKYCPLGLLKNKHGCDICRCKKC 567
Query: 540 PD--------------------CILEEE-------------VFVDGESFSHPR---DPCQ 563
P+ C E + VDG + D C+
Sbjct: 568 PELSCSKICPLGFQQDSHGCLICKCREASASAGPPILSGTCLTVDGHHHKNEESWHDGCR 627
Query: 564 ECRCQEGHAHCQPRPCPRAPCAHPL--PGTCCPNDC-------------SGC-AFGGKEY 607
EC C G C CP C +P PG CCP+ S C A GG+ +
Sbjct: 628 ECYCLNGREMCALITCPVPACGNPTIHPGQCCPSCADDFVVQKPELSTPSICHAPGGEYF 687
Query: 608 PSGADFPHPSDPCRLCRCLSGNVQCLARRCVPLPCPEPVLLPGECCPQCPAAP------- 660
G + D C C C SG V C C PL C P CCPQC P
Sbjct: 688 VEGETWN--IDSCTQCTCHSGRVLCETEVCPPLLCQNPSRTQDSCCPQCTDQPFRPSLSR 745
Query: 661 ---APAGCPRPGAAHARHQEYFSPPGDPCRRCLCLDGSVSCQRLPCPPAPCAHP--RQGP 715
P C E + P D C C+C+D +SC CP C P R+G
Sbjct: 746 NNSVPNYCKNDEGDIFLAAESWKP--DVCTSCICIDSVISCFSESCPSVSCERPVLRKGQ 803
Query: 716 CCPSCDG--------CLYQGKEFASGERFPSPTAACHLCLCWEGSVSCEPKACAPALC-- 765
CCP C C + GK +A ER+ + C C C +G C +C P C
Sbjct: 804 CCPYCIEDTIPKKVVCHFSGKAYADEERWDLDS--CTHCYCLQGQTLCSTVSCPPLPCVE 861
Query: 766 PFPARGDCCPDC 777
P G CCP C
Sbjct: 862 PINVEGSCCPMC 873
Score = 136 bits (342), Expect = 9e-32
Identities = 91/306 (29%), Positives = 119/306 (38%), Gaps = 53/306 (17%)
Query: 104 PEGARWEPDACTACVCQDGAAHCGPQAHLPHCRGCSQNGQTYGNGETFSPDACTTCRCLE 163
P G + + C C C++ +A GP C + +G + N E++ D C C CL
Sbjct: 577 PLGFQQDSHGCLICKCREASASAGPPILSGTC--LTVDGHHHKNEESWH-DGCRECYCLN 633
Query: 164 GTITCNQKPCPRGPCPEP----GACCPHC-------KPGCDYE-------GQLYEEGVTF 205
G C CP C P G CCP C KP G+ + EG T+
Sbjct: 634 GREMCALITCPVPACGNPTIHPGQCCPSCADDFVVQKPELSTPSICHAPGGEYFVEGETW 693
Query: 206 LSSSNPCLQCTCLRSRVRCMALKCPPSPCPEPVLRPGHCCPTCQG--------------- 250
S C QCTC RV C CPP C P CCP C
Sbjct: 694 NIDS--CTQCTCHSGRVLCETEVCPPLLCQNPSRTQDSCCPQCTDQPFRPSLSRNNSVPN 751
Query: 251 -C-TEGGSHWEHGQEWTTPGDPCRICRCLEGHIQCRQRECASL-CPYPARPLPGTCCPVC 307
C + G + + W D C C C++ I C C S+ C P G CCP C
Sbjct: 752 YCKNDEGDIFLAAESWKP--DVCTSCICIDSVISCFSESCPSVSCERPVLR-KGQCCPYC 808
Query: 308 DG--------CFLNGREHRSGEPVGSGDPCSHCRCANGSVQCEPLPCPPVPCRHPGKIPG 359
C +G+ + + E D C+HC C G C + CPP+PC P + G
Sbjct: 809 IEDTIPKKVVCHFSGKAY-ADEERWDLDSCTHCYCLQGQTLCSTVSCPPLPCVEPINVEG 867
Query: 360 QCCPVC 365
CCP+C
Sbjct: 868 SCCPMC 873
Score = 91.3 bits (225), Expect = 3e-18
Identities = 104/383 (27%), Positives = 129/383 (33%), Gaps = 81/383 (21%)
Query: 472 PPGACCPSCDSCTYHSQVYANGQNFTDADSPCHACHCQDGTVT-------------CSLV 518
PPG CCP C + + C CQ G + C L
Sbjct: 199 PPGECCPLPSRCVCN-------------PAGCLRKVCQPGNLNILVSKASGKPGECCDLY 245
Query: 519 DCPP---TTCARPQSGPGQ--CCPRCPDCI-LEEEVFVDGESFSHPRDPCQECRCQEGHA 572
+C P C + P Q CP PD + + DG R C C G
Sbjct: 246 ECKPVFGVDCRTVECPPVQQTACP--PDSYETQVRLTADGCCTLPTRCECLSGLC--GFP 301
Query: 573 HCQPRPCPR-APCAHPLPGTCCP-----NDCS-GCAFGGKEYPSGADFPHPSDPCRLCRC 625
C+ PR PG CC ND C F EY G F D CR CRC
Sbjct: 302 VCEVGSTPRIVSRGDGTPGKCCDVFECVNDTKPACVFNNVEYYDGDMF--RMDNCRFCRC 359
Query: 626 LSGNVQCLARRCVPLPCPEPVLLPGECCPQC--PAAP--APAGCPRPGAAHARHQEYFSP 681
G C +C + C + GECCP C P P PAGC G A +
Sbjct: 360 QGGVAICFTAQCGEINCERYYVPEGECCPVCEDPVYPFNNPAGCYANGLILAHGDRWRE- 418
Query: 682 PGDPCRRCLCLDGSVSCQRLPCPPAPCAHPRQ--GPCCPSCD----------------GC 723
D C C C++G C C C +P + G CCP C+ C
Sbjct: 419 --DDCTFCQCVNGERHCVATVCGQT-CTNPVKVPGECCPVCEEPTIITVDPPACGELSNC 475
Query: 724 LYQGKEFASGERFPSPTAACHLCLCWEGSVSC-EPKACAPALCPFPARGDCCPDCDGEGH 782
GK+ +G F C C C C E K CPF D +C+
Sbjct: 476 TLTGKDCING--FKRDHNGCRTCQCINTEELCSERKQGCTLNCPFGFLTD-AQNCE---- 528
Query: 783 GIGSCRGGMRETRGLGQNNLYCP 805
I CR ++ R + + YCP
Sbjct: 529 -ICECRPRPKKCRPIICDK-YCP 549
Score = 66.2 bits (160), Expect = 1e-10
Identities = 102/443 (23%), Positives = 131/443 (29%), Gaps = 150/443 (33%)
Query: 461 CPPAPCQHPTQPPGA-------CCPSC--------------------------------D 481
C + C+ P PG+ CC +C D
Sbjct: 40 CDESKCEEPRNCPGSIVQGVCGCCYTCASQRNESCGGTFGIYGTCDRGLRCVIRPPLNGD 99
Query: 482 SCTYHSQVYANGQNFTDAD----SPCH-----ACHCQDGTVTCSLVDCPPTTCARPQSGP 532
S T + +N+TD PC+ C+ +G C+ + TC+ P P
Sbjct: 100 SLTEYEAGVCEDENWTDDQLLGFKPCNENLIAGCNIINGKCECNTI----RTCSNPFEFP 155
Query: 533 G-------------------------QCCPRCPDCILEEEVFVDGESFSHPRDPCQECRC 567
Q PRCP E+ V ++G + P EC
Sbjct: 156 SQDMCLSALKRIEEEKPDCSKARCEVQFSPRCP----EDSVLIEGYA------PPGECCP 205
Query: 568 QEGHAHCQPRPCPRAPC-----------AHPLPGTCCP-NDCS---GCAFGGKEYPSGAD 612
C P C R C A PG CC +C G E P
Sbjct: 206 LPSRCVCNPAGCLRKVCQPGNLNILVSKASGKPGECCDLYECKPVFGVDCRTVECPPVQQ 265
Query: 613 FPHPSDP------------CRL---CRCLSGNVQCLARRCVPLPCPEPVL----LPGECC 653
P D C L C CLSG C C P V PG+CC
Sbjct: 266 TACPPDSYETQVRLTADGCCTLPTRCECLSG--LCGFPVCEVGSTPRIVSRGDGTPGKCC 323
Query: 654 P--QCPAAPAPAGCPRPGAAHARHQEYFSPP---GDPCRRCLCLDGSVSCQRLPCPPAPC 708
+C P A + EY+ D CR C C G C C C
Sbjct: 324 DVFECVNDTKP-------ACVFNNVEYYDGDMFRMDNCRFCRCQGGVAICFTAQCGEINC 376
Query: 709 A--HPRQGPCCPSCD----------GCLYQGKEFASGERFPSPTAACHLCLCWEGSVSCE 756
+ +G CCP C+ GC G A G+R+ C C C G C
Sbjct: 377 ERYYVPEGECCPVCEDPVYPFNNPAGCYANGLILAHGDRWREDD--CTFCQCVNGERHCV 434
Query: 757 PKACAPALC-PFPARGDCCPDCD 778
C P G+CCP C+
Sbjct: 435 ATVCGQTCTNPVKVPGECCPVCE 457
>gi|108773804 Fraser syndrome 1 [Homo sapiens]
Length = 4011
Score = 206 bits (523), Expect = 9e-53
Identities = 204/749 (27%), Positives = 260/749 (34%), Gaps = 180/749 (24%)
Query: 130 AHLPHCR--GCSQNGQTYGNGETFSPDACTTCRCLEGTITCNQKPCPRGPCP-EPG---- 182
A LPH C + + PD+C +CRC + C C C E G
Sbjct: 18 AVLPHHSEGACVYQDSLLADATIWKPDSCQSCRCHGDIVICKPAVCRNPQCAFEKGEVLQ 77
Query: 183 ----ACCPHC---KPG-CDYEGQLYEEGVTFLSSSNPCLQCTCLRSRVRCMALKCPPSPC 234
CCP C PG C +E +++E G + SS PC C+C VRC CPP C
Sbjct: 78 IAANQCCPECVLRTPGSCHHEKKIHEHGTEWASS--PCSVCSCNHGEVRCTPQPCPPLSC 135
Query: 235 PEPVLR---PGHCCPTCQG----CTEGGSHWEHGQEWTTPGDPCRICRCLEGHIQCRQRE 287
L G CCP C G C+ G ++ G++W C C C G QC +
Sbjct: 136 GHQELAFIPEGSCCPVCVGLGKPCSYEGHVFQDGEDWRL--SRCAKCLCRNGVAQCFTAQ 193
Query: 288 CASL-CPYPAR--PLPGTCCPVCD--GCFLNGREHRSGEPVGSGDPCSHCRCANGSVQCE 342
C L C +PG CCP C C G+ + GE S + C+ C C G V+C
Sbjct: 194 CQPLFCNQDETVVRVPGKCCPQCSARSCSAAGQVYEHGEQ-WSENACTTCICDRGEVRCH 252
Query: 343 PLPCPPVPC---RHPGKIPGQCCPVC----DGCEYQG-HQYQSQETFRLQERGLCVRCSC 394
C P+ C + + GQCC C C Y G +YQ + + + C C C
Sbjct: 253 KQACLPLRCGKGQSRARRHGQCCEECVSPAGSCSYDGVVRYQDE----MWKGSACEFCMC 308
Query: 395 QAGEVSCEEQECPVTPCA----LPASGRQLCPAC---------ELDGE----------EF 431
G+V+C+ EC CA L + CP C E GE
Sbjct: 309 DHGQVTCQTGECAKVECARDEELIHLDGKCCPECISRNGYCVYEETGEFMSSNASEVKRI 368
Query: 432 AEGVQWEPDGRPCTACVCQDGVPKCGAVLCPPAPC-QHPTQPPGACCPSCDSCTYHSQ-- 488
EG +WE DG PC C C+ C CPP P + G CCP C S H
Sbjct: 369 PEGEKWE-DG-PCKVCECRGAQVTCYEPSCPPCPVGTLALEVKGQCCPDCTSVHCHPDCL 426
Query: 489 ------------------------VYANGQNFTDADSPCHACHCQDGTVTCSL--VDCPP 522
V++ G F A S C AC Q T T L C P
Sbjct: 427 TCSQSPDHCDLCQDPTKLLQNGWCVHSCGLGFYQAGSLCLACQPQCSTCTSGLECSSCQP 486
Query: 523 TTCARPQSGPGQCCPRCPDCILEEEVFVDGESFSHPRDPCQECRCQEGHAHCQPRPCPRA 582
R GQC P C G+ F R C C H C A
Sbjct: 487 PLLMR----HGQCVPTC------------GDGFYQDRHSCAVC-----HESC-------A 518
Query: 583 PCAHPLPGTC--CPNDCSGCAFGGKEYPSGADFPHPSDPCRLCRCLSGNVQCLARRCVPL 640
C P C C + GG E G F + C C + + RC L
Sbjct: 519 GCWGPTEKHCLACRDPLHVLRDGGCESSCGKGFYNRQGTCSACDQSCDSCGPSSPRC--L 576
Query: 641 PCPE-PVLLPGECCPQCPAAPAPAGCPRPGAAHARHQEYFSPPGDPCRRCLCLDGSVSCQ 699
C E VL G+C +CP Y++ C+ +C + SC
Sbjct: 577 TCTEKTVLHDGKCMSECPGG------------------YYADATGRCK--VCHNSCASCS 616
Query: 700 -RLPCPPAPCAHP---RQGPCCPSCDGCLYQGKEFASGERFPSPTAACHLCLCWEGSVSC 755
P C+ P RQG C P C GE F S C C
Sbjct: 617 GPTPSHCTACSPPKALRQGHCLPRC------------GEGFYSDHGVCKAC--------- 655
Query: 756 EPKACAPALCPFPARGDCCPDCDGEGHGI 784
+C + P P+ C C G+
Sbjct: 656 -HSSCLACMGPAPSH---CTGCKKPEEGL 680
Score = 166 bits (421), Expect = 6e-41
Identities = 187/704 (26%), Positives = 235/704 (33%), Gaps = 175/704 (24%)
Query: 88 ECHPASP-QCWGLGRAWPEGARWEPDACTACVCQDGAAHCGPQ----------------- 129
EC +P C + G W C+ C C G C PQ
Sbjct: 86 ECVLRTPGSCHHEKKIHEHGTEWASSPCSVCSCNHGEVRCTPQPCPPLSCGHQELAFIPE 145
Query: 130 -AHLPHCRG----CSQNGQTYGNGETFSPDACTTCRCLEGTITCNQKPCPRGPCPE---- 180
+ P C G CS G + +GE + C C C G C C C +
Sbjct: 146 GSCCPVCVGLGKPCSYEGHVFQDGEDWRLSRCAKCLCRNGVAQCFTAQCQPLFCNQDETV 205
Query: 181 ---PGACCPHCKP-GCDYEGQLYEEGVTFLSSSNPCLQCTCLRSRVRCMALKCPPSPC-- 234
PG CCP C C GQ+YE G + S N C C C R VRC C P C
Sbjct: 206 VRVPGKCCPQCSARSCSAAGQVYEHGEQW--SENACTTCICDRGEVRCHKQACLPLRCGK 263
Query: 235 -PEPVLRPGHCCPTC----QGCTEGGSHWEHGQEWTTPGDPCRICRCLEGHIQCRQRECA 289
R G CC C C+ G + W G C C C G + C+ ECA
Sbjct: 264 GQSRARRHGQCCEECVSPAGSCSYDGVVRYQDEMW--KGSACEFCMCDHGQVTCQTGECA 321
Query: 290 SL-CPYPAR--PLPGTCCPVC-----------DGCFLNGREHR-----SGEPVGSGDPCS 330
+ C L G CCP C G F++ GE G PC
Sbjct: 322 KVECARDEELIHLDGKCCPECISRNGYCVYEETGEFMSSNASEVKRIPEGEKWEDG-PCK 380
Query: 331 HCRCANGSVQCEPLPCPPVPCRHPG-KIPGQCCPVCDG----------CEYQGHQYQSQE 379
C C V C CPP P ++ GQCCP C + H Q+
Sbjct: 381 VCECRGAQVTCYEPSCPPCPVGTLALEVKGQCCPDCTSVHCHPDCLTCSQSPDHCDLCQD 440
Query: 380 TFRLQERGLCVRCSC-----QAGE--VSCEEQ--------ECPVTPCALPASGRQLCPAC 424
+L + G CV SC QAG ++C+ Q EC L Q P C
Sbjct: 441 PTKLLQNGWCVH-SCGLGFYQAGSLCLACQPQCSTCTSGLECSSCQPPLLMRHGQCVPTC 499
Query: 425 ELDG-----------EEFAEGVQWEPDGRPCTAC-----VCQDG--VPKCGAVLC----P 462
DG E G W P + C AC V +DG CG
Sbjct: 500 G-DGFYQDRHSCAVCHESCAGC-WGPTEKHCLACRDPLHVLRDGGCESSCGKGFYNRQGT 557
Query: 463 PAPCQHPTQPPGACCPSCDSCTYHSQVY-------ANGQNFTDADSPCHACHCQDGTVTC 515
+ C G P C +CT + ++ G + DA C CH + +C
Sbjct: 558 CSACDQSCDSCGPSSPRCLTCTEKTVLHDGKCMSECPGGYYADATGRCKVCH--NSCASC 615
Query: 516 S-LVDCPPTTCARPQS-GPGQCCPRCPDCILEEEVFVDGESFSHPRDPCQECRCQEGHAH 573
S T C+ P++ G C PRC GE F C+ C H+
Sbjct: 616 SGPTPSHCTACSPPKALRQGHCLPRC------------GEGFYSDHGVCKAC-----HSS 658
Query: 574 CQPRPCPRAPCAHPLPGTCCPNDCSGC--AFGGKEYPSGADFPHPSDPC-RLCR------ 624
C C P P+ C+GC G + +D PS C CR
Sbjct: 659 C-------LACMGP-----APSHCTGCKKPEEGLQVEQLSDVGIPSGECLAQCRAHFYLE 706
Query: 625 ----CLSGNVQCLARRCV---PLPC----PEPVLLPGECCPQCP 657
C + + C RC P C P VLL G+C QCP
Sbjct: 707 STGICEACHQSCF--RCAGKSPHNCTDCGPSHVLLDGQCLSQCP 748
Score = 120 bits (301), Expect = 5e-27
Identities = 208/922 (22%), Positives = 288/922 (31%), Gaps = 274/922 (29%)
Query: 94 PQCWGLGR-------AWPEGARWEPDACTACVCQDGAAHCG------------------P 128
P C GLG+ + +G W C C+C++G A C P
Sbjct: 150 PVCVGLGKPCSYEGHVFQDGEDWRLSRCAKCLCRNGVAQCFTAQCQPLFCNQDETVVRVP 209
Query: 129 QAHLPHC--RGCSQNGQTYGNGETFSPDACTTCRCLEGTITCNQKPCPRGPCPEP----- 181
P C R CS GQ Y +GE +S +ACTTC C G + C+++ C C +
Sbjct: 210 GKCCPQCSARSCSAAGQVYEHGEQWSENACTTCICDRGEVRCHKQACLPLRCGKGQSRAR 269
Query: 182 --GACCPHCKP---GCDYEGQLYEEGVTFLSSSNPCLQCTCLRSRVRCMALKCPPSPCP- 235
G CC C C Y+G + + + S+ C C C +V C +C C
Sbjct: 270 RHGQCCEECVSPAGSCSYDGVVRYQDEMWKGSA--CEFCMCDHGQVTCQTGECAKVECAR 327
Query: 236 --EPVLRPGHCCPTCQG----CT--EGGSHWE----------HGQEWTTPGDPCRICRCL 277
E + G CCP C C E G G++W PC++C C
Sbjct: 328 DEELIHLDGKCCPECISRNGYCVYEETGEFMSSNASEVKRIPEGEKWED--GPCKVCECR 385
Query: 278 EGHIQCRQRECASLCPYP--ARPLPGTCCPVCDGCFLNGREHRSGEPVGSGDPCSHCR-- 333
+ C + C CP A + G CCP C + + S D C C+
Sbjct: 386 GAQVTCYEPSCPP-CPVGTLALEVKGQCCPDCTSVHCHPDCLTCSQ---SPDHCDLCQDP 441
Query: 334 ------------CANGSVQ-------CEP--------LPC----PPVPCRHPGKIPGQCC 362
C G Q C+P L C PP+ RH GQC
Sbjct: 442 TKLLQNGWCVHSCGLGFYQAGSLCLACQPQCSTCTSGLECSSCQPPLLMRH-----GQCV 496
Query: 363 PVCDGCEYQG--------------------HQYQSQETFRLQERGLCVRCSC------QA 396
P C YQ H ++ + G C SC +
Sbjct: 497 PTCGDGFYQDRHSCAVCHESCAGCWGPTEKHCLACRDPLHVLRDGGC-ESSCGKGFYNRQ 555
Query: 397 GEVSCEEQEC----PVTPCALPASGRQLCPACELDGEEFAE---GVQWEPDGR------- 442
G S +Q C P +P L + + + DG+ +E G + GR
Sbjct: 556 GTCSACDQSCDSCGPSSPRCLTCTEKTVLH----DGKCMSECPGGYYADATGRCKVCHNS 611
Query: 443 ----------PCTAC----VCQDG--VPKCG----------------AVLCP-PAP---- 465
CTAC + G +P+CG + C PAP
Sbjct: 612 CASCSGPTPSHCTACSPPKALRQGHCLPRCGEGFYSDHGVCKACHSSCLACMGPAPSHCT 671
Query: 466 -CQHPTQ------------PPGACCPSCDSCTYHSQVYANGQNFTDADSPCHACHCQ--- 509
C+ P + P G C C + Y ++ C ACH
Sbjct: 672 GCKKPEEGLQVEQLSDVGIPSGECLAQCRAHFY-----------LESTGICEACHQSCFR 720
Query: 510 -DGTVTCSLVDCPPTTCARPQSGPGQCCPRCPDCILEEEVFVDGESFSHPRDPCQECR-- 566
G + DC P+ GQC +CPD + H C EC
Sbjct: 721 CAGKSPHNCTDCGPSHVLLD----GQCLSQCPD------------GYFHQEGSCTECHPT 764
Query: 567 CQEGHA-------HCQPR------PCPRAPCAHP----LPGTC--CPNDCSGCAFGGKEY 607
C++ H C P C R C L G C C + C CA
Sbjct: 765 CRQCHGPLESDCISCYPHISLTNGNC-RTSCREEQFLNLVGYCADCHHLCQHCA------ 817
Query: 608 PSGADFPHPSDPCRLCRCLSGNVQCLARRCVPLPCPEPVLLPGECCPQCPAAPAPAGCPR 667
AD + C RC + + L CVP CP C +C ++
Sbjct: 818 ---ADLHNTGSIC--LRCQNAHYLLLGDHCVP-DCPSGYYAERGACKKCHSSCRTCQGRG 871
Query: 668 PGAAHARHQEYFSPPGDPCRRCLCLDGSVSCQRLPCPPAPCAHPRQGPCCPSCDGCLYQG 727
P + + C C G C P H SC C
Sbjct: 872 PFSCSSCDTNLVLSHTGTC-STTCFPGHYLDDNHVCQPCN-THCGSCDSQASCTSCRDPN 929
Query: 728 KEFASGE-RFPSPTAACHLCLCWEGSVSCEPKACAPALCPFPARGDCCPDCDG----EGH 782
K GE ++ S +L C+ A C P + DC DG +G
Sbjct: 930 KVLLFGECQYESCAPQYYLDFSTNTCKECDWSCSA---CSGPLKTDCLQCMDGYVLQDGA 986
Query: 783 GIGSCRGGMRETRGLGQNNLYC 804
+ C + GL + + YC
Sbjct: 987 CVEQCLSSFYQDSGLCKCDSYC 1008
Score = 34.3 bits (77), Expect = 0.48
Identities = 46/208 (22%), Positives = 62/208 (29%), Gaps = 48/208 (23%)
Query: 118 VCQDGAAHCGPQAHLPHCRGCSQNGQTYGNGET------------FSPDACT----TCRC 161
VCQ HCG C C + GE FS + C +C
Sbjct: 905 VCQPCNTHCGSCDSQASCTSCRDPNKVLLFGECQYESCAPQYYLDFSTNTCKECDWSCSA 964
Query: 162 LEGTITCNQKPCPRGPCPEPGACCPHCKPGCDYEGQLYEEGVTFLSSSNPCLQCTCLRSR 221
G + + C G + GAC C Y++ + CLQC
Sbjct: 965 CSGPLKTDCLQCMDGYVLQDGACVEQCL------SSFYQDS-GLCKCDSYCLQCQGPHEC 1017
Query: 222 VRCMALKCPPSPCPEPVLRPGHCCPTCQGCTEG--GSHWEHGQEWTTPGDPCRICRCLEG 279
RC P L C Q C +G H +H + C +G
Sbjct: 1018 TRCKG----------PFLLLEAQC--VQECGKGYFADHAKH-----------KCTACPQG 1054
Query: 280 HIQCRQRECASLCPYPARPLPGTCCPVC 307
+QC R+ LC + G C C
Sbjct: 1055 CLQCSHRDRCHLCDHGFFLKSGLCVYNC 1082
Score = 32.3 bits (72), Expect = 1.8
Identities = 54/251 (21%), Positives = 80/251 (31%), Gaps = 67/251 (26%)
Query: 125 HCGPQ------AHLPHCRGCSQNGQTYGNGETFSPDACTTCRCLEGTITCNQ-------- 170
HC P A C+ C + +T FS +C T L T TC+
Sbjct: 841 HCVPDCPSGYYAERGACKKCHSSCRTCQGRGPFSCSSCDTNLVLSHTGTCSTTCFPGHYL 900
Query: 171 ------KPCPR--GPCPEPGACCPHCKPG-------CDYEGQLYEEGVTFLSSSNPCLQ- 214
+PC G C +C P C YE + + F S+N C +
Sbjct: 901 DDNHVCQPCNTHCGSCDSQASCTSCRDPNKVLLFGECQYESCAPQYYLDF--STNTCKEC 958
Query: 215 ---CTCLRSRVRCMALKCPPSPCPEPVLRPGHCCPTCQGCTEGGSHWEHGQEWTTPGDPC 271
C+ ++ L+C VL+ G C C S
Sbjct: 959 DWSCSACSGPLKTDCLQCMDG----YVLQDGACVEQCLSSFYQDS--------------- 999
Query: 272 RICRCLEGHIQCRQRECASLCPYPARPLPGTCCPVC-DGCFLNGREHRSGEPVGSGDPCS 330
+C+C +QC+ + C P L C C G F + +H+ C+
Sbjct: 1000 GLCKCDSYCLQCQGPHECTRCKGPFLLLEAQCVQECGKGYFADHAKHK----------CT 1049
Query: 331 HCRCANGSVQC 341
C G +QC
Sbjct: 1050 --ACPQGCLQC 1058
>gi|37693519 BMP-binding endothelial regulator precursor protein
[Homo sapiens]
Length = 685
Score = 152 bits (383), Expect = 2e-36
Identities = 95/318 (29%), Positives = 133/318 (41%), Gaps = 39/318 (12%)
Query: 192 CDYEGQLYEEGVTFLSSSNPCLQCTCLRSRVRCMALKCP--PSPCPEPVLRPGHCCPTCQ 249
C+ EG++ + + F++ NPC+ C CL V C KCP C + + G CC C+
Sbjct: 50 CENEGEVLQ--IPFITD-NPCIMCVCLNKEVTCKREKCPVLSRDCALAIKQRGACCEQCK 106
Query: 250 GCTEGGSHWEHGQEWTTPGDPCRICRCLEGHIQCRQRECASLCPYPARPLPGTCCPVCDG 309
GCT G+ + +W +P +PC + +C EG + C C P L G CCP C G
Sbjct: 107 GCTYEGNTYNSSFKWQSPAEPCVLRQCQEGVVTESGVRCVVHCKNPLEHL-GMCCPTCPG 165
Query: 310 CFLNGREHRSGEPV-GSGDPCSHCRCANGSVQCEPLPCPPVPC-RHPGKI-PGQCCPVCD 366
C G +++ GE G C+ C C G QC CP + C +H I PGQCCP C
Sbjct: 166 CVFEGVQYQEGEEFQPEGSKCTKCSCTGGRTQCVREVCPILSCPQHLSHIPPGQCCPKCL 225
Query: 367 G-----------CEYQGHQYQSQETFRLQERGLCVRCSCQAGEVSCEE-----------Q 404
G C ++ Y + +F C C+C+ V C+ Q
Sbjct: 226 GQRKVFDLPFGSCLFRSDVYDNGSSFLYDN---CTACTCRDSTVVCKRKCSHPGGCDQGQ 282
Query: 405 ECPVTPCALPASGRQLCPACELDGEEFAEGVQWEPDGRPCTACVCQDGVPKCGAVLC-PP 463
E C L + C+ + F +G W CT C C G +C C P
Sbjct: 283 EGCCEECLLRVPPEDI-KVCKFGNKIFQDGEMWSSIN--CTICACVKGRTECRNKQCIPI 339
Query: 464 APC-QHPTQPPGACCPSC 480
+ C Q CCP C
Sbjct: 340 SSCPQGKILNRKGCCPIC 357
Score = 150 bits (380), Expect = 3e-36
Identities = 112/346 (32%), Positives = 148/346 (42%), Gaps = 66/346 (19%)
Query: 297 RPLPG-TCCPV----CDGC-------FLNG---REHRSGE----PVGSGDPCSHCRCANG 337
R PG TCC + C G FL G + GE P + +PC C C N
Sbjct: 16 RRSPGITCCVLLLLNCSGVPMSLASSFLTGSVAKCENEGEVLQIPFITDNPCIMCVCLNK 75
Query: 338 SVQCEPLPCPPVP--CRHPGKIPGQCCPVCDGCEYQGHQYQSQETFRLQERGL-CVRCSC 394
V C+ CP + C K G CC C GC Y+G+ Y S +F+ Q CV C
Sbjct: 76 EVTCKREKCPVLSRDCALAIKQRGACCEQCKGCTYEGNTYNS--SFKWQSPAEPCVLRQC 133
Query: 395 QAGEVSCEEQECPVTPCALPASGRQLC----PACELDGEEFAEGVQWEPDGRPCTACVCQ 450
Q G V+ C V C P +C P C +G ++ EG +++P+G CT C C
Sbjct: 134 QEGVVTESGVRC-VVHCKNPLEHLGMCCPTCPGCVFEGVQYQEGEEFQPEGSKCTKCSCT 192
Query: 451 DGVPKCGAVLCPPAPC-QHPTQ-PPGACCPSC-----------DSCTYHSQVYANGQNFT 497
G +C +CP C QH + PPG CCP C SC + S VY NG +F
Sbjct: 193 GGRTQCVREVCPILSCPQHLSHIPPGQCCPKCLGQRKVFDLPFGSCLFRSDVYDNGSSFL 252
Query: 498 DADSPCHACHCQDGTVTCSLVDCPPTTCARPQSGPGQCCPRC-----PD----CILEEEV 548
+ C AC C+D TV C P C + Q G CC C P+ C ++
Sbjct: 253 YDN--CTACTCRDSTVVCKRKCSHPGGCDQGQEG---CCEECLLRVPPEDIKVCKFGNKI 307
Query: 549 FVDGESFSHPRDPCQECRCQEGHAHCQPRPCPRAPCAHPLPGTCCP 594
F DGE +S C C C +G C+ + C +P + CP
Sbjct: 308 FQDGEMWSSIN--CTICACVKGRTECRNKQC--------IPISSCP 343
Score = 150 bits (380), Expect = 3e-36
Identities = 96/300 (32%), Positives = 124/300 (41%), Gaps = 28/300 (9%)
Query: 500 DSPCHACHCQDGTVTCSLVDCPPTT--CARPQSGPGQCCPRCPDCILEEEVFVDGESFSH 557
D+PC C C + VTC CP + CA G CC +C C E + +
Sbjct: 64 DNPCIMCVCLNKEVTCKREKCPVLSRDCALAIKQRGACCEQCKGCTYEGNTYNSSFKWQS 123
Query: 558 PRDPCQECRCQEGHAHCQPRPCPRAPCAHPLP--GTCCPNDCSGCAFGGKEYPSGADFPH 615
P +PC +CQEG C C +PL G CCP C GC F G +Y G +F
Sbjct: 124 PAEPCVLRQCQEGVVTESGVRCV-VHCKNPLEHLGMCCPT-CPGCVFEGVQYQEGEEFQP 181
Query: 616 PSDPCRLCRCLSGNVQCLARRCVPLPCPEPV--LLPGECCPQCPAAPAPAGCPRPGAAHA 673
C C C G QC+ C L CP+ + + PG+CCP+C P G+
Sbjct: 182 EGSKCTKCSCTGGRTQCVREVCPILSCPQHLSHIPPGQCCPKCLGQRKVFDLPF-GSCLF 240
Query: 674 RHQEYFSPPG---DPCRRCLCLDGSVSCQRLPCPPAPCAHPRQGPCCPSC---------D 721
R Y + D C C C D +V C+R P C ++G CC C
Sbjct: 241 RSDVYDNGSSFLYDNCTACTCRDSTVVCKRKCSHPGGCDQGQEG-CCEECLLRVPPEDIK 299
Query: 722 GCLYQGKEFASGERFPSPTAACHLCLCWEGSVSCEPKACAP-ALCP---FPARGDCCPDC 777
C + K F GE + S C +C C +G C K C P + CP R CCP C
Sbjct: 300 VCKFGNKIFQDGEMWSSIN--CTICACVKGRTECRNKQCIPISSCPQGKILNRKGCCPIC 357
Score = 137 bits (344), Expect = 5e-32
Identities = 92/318 (28%), Positives = 118/318 (37%), Gaps = 31/318 (9%)
Query: 424 CELDGEEFAEGVQWEPDGRPCTACVCQDGVPKCGAVLCP--PAPCQHPTQPPGACCPSCD 481
CE +GE + + D PC CVC + C CP C + GACC C
Sbjct: 50 CENEGEVLQ--IPFITDN-PCIMCVCLNKEVTCKREKCPVLSRDCALAIKQRGACCEQCK 106
Query: 482 SCTYHSQVYANGQNFTDADSPCHACHCQDGTVTCSLVDCPPTTCARPQSGPGQCCPRCPD 541
CTY Y + + PC CQ+G VT S V C C P G CCP CP
Sbjct: 107 GCTYEGNTYNSSFKWQSPAEPCVLRQCQEGVVTESGVRCV-VHCKNPLEHLGMCCPTCPG 165
Query: 542 CILEEEVFVDGESFSHPRDPCQECRCQEGHAHCQPRPCPRAPC----AHPLPGTCCPNDC 597
C+ E + +GE F C +C C G C CP C +H PG CCP C
Sbjct: 166 CVFEGVQYQEGEEFQPEGSKCTKCSCTGGRTQCVREVCPILSCPQHLSHIPPGQCCPK-C 224
Query: 598 SG-----------CAFGGKEYPSGADFPHPSDPCRLCRCLSGNVQCLARRCVPLPCPEPV 646
G C F Y +G+ F + D C C C V C + P C +
Sbjct: 225 LGQRKVFDLPFGSCLFRSDVYDNGSSFLY--DNCTACTCRDSTVVCKRKCSHPGGCDQG- 281
Query: 647 LLPGECCPQCPAAPAPAGCPRPGAAHARHQEYFSPPGDPCRRCLCLDGSVSCQRLPC-PP 705
CC +C P + Q+ C C C+ G C+ C P
Sbjct: 282 --QEGCCEECLLRVPPEDIKVCKFGNKIFQDGEMWSSINCTICACVKGRTECRNKQCIPI 339
Query: 706 APCAHPR---QGPCCPSC 720
+ C + + CCP C
Sbjct: 340 SSCPQGKILNRKGCCPIC 357
Score = 132 bits (333), Expect = 1e-30
Identities = 89/303 (29%), Positives = 122/303 (40%), Gaps = 46/303 (15%)
Query: 156 CTTCRCLEGTITCNQKPCP--RGPCP----EPGACCPHCKPGCDYEGQLYEEGVTFLSSS 209
C C CL +TC ++ CP C + GACC CK GC YEG Y + S +
Sbjct: 67 CIMCVCLNKEVTCKREKCPVLSRDCALAIKQRGACCEQCK-GCTYEGNTYNSSFKWQSPA 125
Query: 210 NPCLQCTCLRSRVRCMALKCPPSPCPEPVLRPGHCCPTCQGCTEGGSHWEHGQEWTTPGD 269
PC+ C V ++C C P+ G CCPTC GC G ++ G+E+ G
Sbjct: 126 EPCVLRQCQEGVVTESGVRCVVH-CKNPLEHLGMCCPTCPGCVFEGVQYQEGEEFQPEGS 184
Query: 270 PCRICRCLEGHIQCRQRECASL-CPYPARPL-PGTCCPVCDG-----------CFLNGRE 316
C C C G QC + C L CP + PG CCP C G C
Sbjct: 185 KCTKCSCTGGRTQCVREVCPILSCPQHLSHIPPGQCCPKCLGQRKVFDLPFGSCLFRSDV 244
Query: 317 HRSGEPVGSGDPCSHCRCANGSVQCEPLPCPPVPCRHPGKI-PGQ--CCPVC-------- 365
+ +G D C+ C C + +V C+ C HPG GQ CC C
Sbjct: 245 YDNGSSF-LYDNCTACTCRDSTVVCKR------KCSHPGGCDQGQEGCCEECLLRVPPED 297
Query: 366 -DGCEYQGHQYQSQETFRLQERGLCVRCSCQAGEVSCEEQEC-PVTPC--ALPASGRQLC 421
C++ +Q E + C C+C G C ++C P++ C + + C
Sbjct: 298 IKVCKFGNKIFQDGEMWSSIN---CTICACVKGRTECRNKQCIPISSCPQGKILNRKGCC 354
Query: 422 PAC 424
P C
Sbjct: 355 PIC 357
Score = 122 bits (306), Expect = 1e-27
Identities = 81/283 (28%), Positives = 118/283 (41%), Gaps = 47/283 (16%)
Query: 114 CTACVCQDGAAHCGPQAHLPHCRGCSQNGQTYGNGETFSPDA--CTTCRCLEGTITCNQK 171
C + Q GA C Q C+GC+ G TY + + A C +C EG +T +
Sbjct: 91 CALAIKQRGA--CCEQ-----CKGCTYEGNTYNSSFKWQSPAEPCVLRQCQEGVVTESGV 143
Query: 172 PCP---RGPCPEPGACCPHCKPGCDYEGQLYEEGVTFLSSSNPCLQCTCLRSRVRCMALK 228
C + P G CCP C PGC +EG Y+EG F + C +C+C R +C+
Sbjct: 144 RCVVHCKNPLEHLGMCCPTC-PGCVFEGVQYQEGEEFQPEGSKCTKCSCTGGRTQCVREV 202
Query: 229 CPPSPCPEPV--LRPGHCCPTCQG-----------CTEGGSHWEHGQEWTTPGDPCRICR 275
CP CP+ + + PG CCP C G C +++G + D C C
Sbjct: 203 CPILSCPQHLSHIPPGQCCPKCLGQRKVFDLPFGSCLFRSDVYDNGSSFLY--DNCTACT 260
Query: 276 CLEGHIQCRQRECASLCPYPARPLPGT--CCPVC---------DGCFLNGREHRSGEPVG 324
C + + C+++ C +P G CC C C + + GE +
Sbjct: 261 CRDSTVVCKRK-----CSHPGGCDQGQEGCCEECLLRVPPEDIKVCKFGNKIFQDGE-MW 314
Query: 325 SGDPCSHCRCANGSVQCEPLPCPPVPCRHPGKIPGQ--CCPVC 365
S C+ C C G +C C P+ GKI + CCP+C
Sbjct: 315 SSINCTICACVKGRTECRNKQCIPISSCPQGKILNRKGCCPIC 357
Score = 92.8 bits (229), Expect = 1e-18
Identities = 53/171 (30%), Positives = 76/171 (44%), Gaps = 16/171 (9%)
Query: 618 DPCRLCRCLSGNVQCLARRCVPLP--CPEPVLLPGECCPQCPAAPAPAGCPRPGAAHARH 675
+PC +C CL+ V C +C L C + G CC QC GC G +
Sbjct: 65 NPCIMCVCLNKEVTCKREKCPVLSRDCALAIKQRGACCEQCK------GCTYEGNTYNSS 118
Query: 676 QEYFSPPGDPCRRCLCLDGSVSCQRLPCPPAPCAHPRQ--GPCCPSCDGCLYQGKEFASG 733
++ SP +PC C +G V+ + C C +P + G CCP+C GC+++G ++ G
Sbjct: 119 FKWQSP-AEPCVLRQCQEGVVTESGVRCV-VHCKNPLEHLGMCCPTCPGCVFEGVQYQEG 176
Query: 734 ERFPSPTAACHLCLCWEGSVSCEPKACAPALCP----FPARGDCCPDCDGE 780
E F + C C C G C + C CP G CCP C G+
Sbjct: 177 EEFQPEGSKCTKCSCTGGRTQCVREVCPILSCPQHLSHIPPGQCCPKCLGQ 227
Score = 85.5 bits (210), Expect = 2e-16
Identities = 62/240 (25%), Positives = 92/240 (38%), Gaps = 51/240 (21%)
Query: 58 EWLGRLEAAVMELREQNKDLQTRVRQLESCE--------CHPASPQCWGLGRAWPEGARW 109
+W E V+ ++ ++ VR + C+ C P P C G + EG +
Sbjct: 120 KWQSPAEPCVLRQCQEGVVTESGVRCVVHCKNPLEHLGMCCPTCPGCVFEGVQYQEGEEF 179
Query: 110 EPDA--CTACVCQDGAAHCGPQA--------HLPH---------CRG-----------CS 139
+P+ CT C C G C + HL H C G C
Sbjct: 180 QPEGSKCTKCSCTGGRTQCVREVCPILSCPQHLSHIPPGQCCPKCLGQRKVFDLPFGSCL 239
Query: 140 QNGQTYGNGETFSPDACTTCRCLEGTITCNQKPCPRGPCPE-PGACCPHCK--------P 190
Y NG +F D CT C C + T+ C +K G C + CC C
Sbjct: 240 FRSDVYDNGSSFLYDNCTACTCRDSTVVCKRKCSHPGGCDQGQEGCCEECLLRVPPEDIK 299
Query: 191 GCDYEGQLYEEGVTFLSSSNPCLQCTCLRSRVRCMALKC-PPSPCPE-PVLRPGHCCPTC 248
C + +++++G + SS C C C++ R C +C P S CP+ +L CCP C
Sbjct: 300 VCKFGNKIFQDGEMW--SSINCTICACVKGRTECRNKQCIPISSCPQGKILNRKGCCPIC 357
>gi|222352166 nel-like 1 isoform 2 precursor [Homo sapiens]
Length = 763
Score = 133 bits (335), Expect = 6e-31
Identities = 138/520 (26%), Positives = 193/520 (37%), Gaps = 113/520 (21%)
Query: 134 HC-RGCSQNGQTYGNGETF-SPDACTTCRCLEGTITCNQKPCPRGPCPEP-------GAC 184
HC + C +G Y + +++ D C C C G + C + CP C G C
Sbjct: 268 HCEKTCQVSGLLYRDQDSWVDGDHCRNCTCKSGAVECRRMSCPPLNCSPDSLPVHIAGQC 327
Query: 185 CPHCKPGCDYEGQLYEEGVTFLSSSNPCLQCTCLRSRVRCMALK-CPPSPCPEP--VLRP 241
C C+P C Y G++ EG L+ S C +C R V + CPP C E +L
Sbjct: 328 CKVCRPKCIYGGKVLAEGQRILTKS--CREC---RGGVLVKITEMCPPLNCSEKDHILPE 382
Query: 242 GHCCPTCQG---CTEGGSHWEHGQ--EWTTPGDPCRICRCLEGHIQCRQ--------REC 288
CC C+G C EG E+ + W T C C G+I + EC
Sbjct: 383 NQCCRVCRGHNFCAEGPKCGENSECKNWNTKA----TCECKSGYISVQGDSAYCEDIDEC 438
Query: 289 ASLCPY-----PARPLPGTCCPVCDGCFLNGREHRSGE--PVGSGD-PCSHCRCANGSVQ 340
A+ Y LPG C ++ + E GSG C +VQ
Sbjct: 439 AAKMHYCHANTVCVNLPGLYRCDCVPGYIRVDDFSCTEHDECGSGQHNCDENAICTNTVQ 498
Query: 341 CEPLPCPPVPCRHPGKIPGQCCPVCDGCEYQGHQYQSQETFRLQERGLCV---RCSCQAG 397
C P + G I C +GC Y G CV +C C +G
Sbjct: 499 GHSCTCKPGYVGN-GTICRAFCE--EGCRY---------------GGTCVAPNKCVCPSG 540
Query: 398 EVS--CEE--QECPV--------TPCALPASGRQ-LCPA-------CELDGEEFAEGVQW 437
CE+ EC + + C A G LCP+ C +G G W
Sbjct: 541 FTGSHCEKDIDECALRTHTCWNDSACINLAGGFDCLCPSGPSCSGDCPHEGGLKHNGQVW 600
Query: 438 EPDGRPCTACVCQDGVPKCGAVLCPPAPCQHPTQPPGACCPSCDS-----CTYHS--QVY 490
C+ C C+DG C C CQ+P+ CCP CD+ C + ++Y
Sbjct: 601 TLKEDRCSVCSCKDGKIFCRRTAC---DCQNPSADL-FCCPECDTRVTSQCLDQNGHKLY 656
Query: 491 ANGQNFTDADSPCHACHCQDGTVTCSLVDCPPTTCARPQSGPGQCCPRC-PDCILEEEVF 549
+G N+T + C C C +G V C + CP +C G+CCPRC D L + +
Sbjct: 657 RSGDNWTHS---CQQCRCLEGEVDCWPLTCPNLSCEYTAILEGECCPRCVSDPCLADNIT 713
Query: 550 VD---------------GESFSHPRDPCQECRCQEGHAHC 574
D G ++ PC C+C+ G C
Sbjct: 714 YDIRKTCLDSYGVSRLSGSVWTMAGSPCTTCKCKNGRVCC 753
Score = 125 bits (315), Expect = 1e-28
Identities = 123/493 (24%), Positives = 175/493 (35%), Gaps = 116/493 (23%)
Query: 310 CFLNGREHRSGEPVGSGDPCSHCRCANGSVQCEPLPCPPVPCRH---PGKIPGQCCPVC- 365
C ++G +R + GD C +C C +G+V+C + CPP+ C P I GQCC VC
Sbjct: 273 CQVSGLLYRDQDSWVDGDHCRNCTCKSGAVECRRMSCPPLNCSPDSLPVHIAGQCCKVCR 332
Query: 366 DGCEYQGH-----QYQSQETFRLQERGLCVRCSCQAGEVSCEEQE--CPVTPCALPASGR 418
C Y G Q ++ R G+ V+ + ++C E++ P C G
Sbjct: 333 PKCIYGGKVLAEGQRILTKSCRECRGGVLVKITEMCPPLNCSEKDHILPENQCCRVCRGH 392
Query: 419 QLCPACELDGEEFAEGVQWEPDGRPCTACVCQDG-------------VPKCGA------- 458
C GE +E W C C+ G + +C A
Sbjct: 393 NFCAEGPKCGEN-SECKNWNTKA----TCECKSGYISVQGDSAYCEDIDECAAKMHYCHA 447
Query: 459 -VLCPPAPCQHPTQ-PPGACCPSCDSCTYHSQVYANGQNFTDADSPC------HACHCQD 510
+C P + PG SCT H + +GQ+ D ++ C H+C C+
Sbjct: 448 NTVCVNLPGLYRCDCVPGYIRVDDFSCTEHDEC-GSGQHNCDENAICTNTVQGHSCTCKP 506
Query: 511 GTV---TCSLVDCP-----------PTTCARPQSGPGQCCPR------------------ 538
G V T C P C P G C +
Sbjct: 507 GYVGNGTICRAFCEEGCRYGGTCVAPNKCVCPSGFTGSHCEKDIDECALRTHTCWNDSAC 566
Query: 539 ----------CP-------DCILEEEVFVDGESFSHPRDPCQECRCQEGHAHCQPRPCPR 581
CP DC E + +G+ ++ D C C C++G C+ C
Sbjct: 567 INLAGGFDCLCPSGPSCSGDCPHEGGLKHNGQVWTLKEDRCSVCSCKDGKIFCRRTACD- 625
Query: 582 APCAHPLPGTCCPNDC-----SGCAF--GGKEYPSGADFPHPSDPCRLCRCLSGNVQCLA 634
C +P C +C S C G K Y SG ++ H C+ CRCL G V C
Sbjct: 626 --CQNPSADLFCCPECDTRVTSQCLDQNGHKLYRSGDNWTHS---CQQCRCLEGEVDCWP 680
Query: 635 RRCVPLPCPEPVLLPGECCPQCPAAPAPAG---------CPRPGAAHARHQEYFSPPGDP 685
C L C +L GECCP+C + P A C ++ G P
Sbjct: 681 LTCPNLSCEYTAILEGECCPRCVSDPCLADNITYDIRKTCLDSYGVSRLSGSVWTMAGSP 740
Query: 686 CRRCLCLDGSVSC 698
C C C +G V C
Sbjct: 741 CTTCKCKNGRVCC 753
Score = 107 bits (268), Expect = 3e-23
Identities = 118/465 (25%), Positives = 152/465 (32%), Gaps = 146/465 (31%)
Query: 424 CELDGEEFAEGVQWEPDGRPCTACVCQDGVPKCGAVLCPPAPCQHPTQP---PGACCPSC 480
C++ G + + W DG C C C+ G +C + CPP C + P G CC C
Sbjct: 273 CQVSGLLYRDQDSWV-DGDHCRNCTCKSGAVECRRMSCPPLNCSPDSLPVHIAGQCCKVC 331
Query: 481 -DSCTYHSQVYANGQNFTDADSPCHACHCQDGTVTCSLVD-CPPTTCARPQS--GPGQCC 536
C Y +V A GQ C C G V + + CPP C+ QCC
Sbjct: 332 RPKCIYGGKVLAEGQRILTKS--CRECR---GGVLVKITEMCPPLNCSEKDHILPENQCC 386
Query: 537 PRC---------PDCILEEE----------------VFVDGES--------------FSH 557
C P C E + V G+S + H
Sbjct: 387 RVCRGHNFCAEGPKCGENSECKNWNTKATCECKSGYISVQGDSAYCEDIDECAAKMHYCH 446
Query: 558 PRDPC------QECRCQEGHAHCQPRPCPR--------------APCAHPLPG------- 590
C C C G+ C A C + + G
Sbjct: 447 ANTVCVNLPGLYRCDCVPGYIRVDDFSCTEHDECGSGQHNCDENAICTNTVQGHSCTCKP 506
Query: 591 ------TCCPNDCS-GCAFGGK-------EYPSGADFPHPS---DPCRL----------C 623
T C C GC +GG PSG H D C L C
Sbjct: 507 GYVGNGTICRAFCEEGCRYGGTCVAPNKCVCPSGFTGSHCEKDIDECALRTHTCWNDSAC 566
Query: 624 RCLSGNVQCLARRCVPLPCPEPVLLPGECCPQCPAAPAPAG-CPRPGAAHARHQEYFSPP 682
L+G CL CP+ P+ +G CP G Q + +
Sbjct: 567 INLAGGFDCL----------------------CPSGPSCSGDCPHEGGLKHNGQVW-TLK 603
Query: 683 GDPCRRCLCLDGSVSCQRLPCPPAPCAHPRQGP-CCPSCDG-----CLYQG--KEFASGE 734
D C C C DG + C+R C C +P CCP CD CL Q K + SG+
Sbjct: 604 EDRCSVCSCKDGKIFCRRTACD---CQNPSADLFCCPECDTRVTSQCLDQNGHKLYRSGD 660
Query: 735 RFPSPTAACHLCLCWEGSVSCEPKACAPALCPFPA--RGDCCPDC 777
+ T +C C C EG V C P C C + A G+CCP C
Sbjct: 661 NW---THSCQQCRCLEGEVDCWPLTCPNLSCEYTAILEGECCPRC 702
Score = 97.1 bits (240), Expect = 6e-20
Identities = 88/315 (27%), Positives = 115/315 (36%), Gaps = 62/315 (19%)
Query: 119 CQDGAAHCGPQAHLPHC---RGCSQNGQTYGNGETFSPDACTTCRCLEGTITCNQKPCPR 175
C G +C A + C+ GNG T CR C +
Sbjct: 480 CGSGQHNCDENAICTNTVQGHSCTCKPGYVGNG--------TICRAF-----CEEGCRYG 526
Query: 176 GPCPEPGAC-CPHCKPGCDYEGQLYEEGVTFLSSSNPCLQCTCLRSRVRCMALKCPPSPC 234
G C P C CP G E + E + + N C L C+ CP P
Sbjct: 527 GTCVAPNKCVCPSGFTGSHCEKDIDECALRTHTCWNDSA-CINLAGGFDCL---CPSGP- 581
Query: 235 PEPVLRPGHCCPTCQG-CTEGGSHWEHGQEWTTPGDPCRICRCLEGHIQCRQRECASLCP 293
+C G C G +GQ WT D C +C C +G I CR+ C C
Sbjct: 582 ------------SCSGDCPHEGGLKHNGQVWTLKEDRCSVCSCKDGKIFCRRTACD--CQ 627
Query: 294 YPARPLPGTCCPVCDGCFLNGREHRSGEPV-GSGD----PCSHCRCANGSVQCEPLPCPP 348
P+ L CCP CD + ++G + SGD C CRC G V C PL CP
Sbjct: 628 NPSADL--FCCPECDTRVTSQCLDQNGHKLYRSGDNWTHSCQQCRCLEGEVDCWPLTCPN 685
Query: 349 VPCRHPGKIPGQCCPVC--DGCEYQGHQYQSQETFRLQERGL--------------CVRC 392
+ C + + G+CCP C D C Y ++T L G+ C C
Sbjct: 686 LSCEYTAILEGECCPRCVSDPCLADNITYDIRKTC-LDSYGVSRLSGSVWTMAGSPCTTC 744
Query: 393 SCQAGEVSCE-EQEC 406
C+ G V C + EC
Sbjct: 745 KCKNGRVCCSVDFEC 759
Score = 66.2 bits (160), Expect = 1e-10
Identities = 53/181 (29%), Positives = 67/181 (37%), Gaps = 45/181 (24%)
Query: 87 CECHPASPQCWG----LGRAWPEGARW--EPDACTACVCQDGAAHC--------GPQAHL 132
C C P+ P C G G G W + D C+ C C+DG C P A L
Sbjct: 575 CLC-PSGPSCSGDCPHEGGLKHNGQVWTLKEDRCSVCSCKDGKIFCRRTACDCQNPSADL 633
Query: 133 PHCRGC---------SQNG-QTYGNGETFSPDACTTCRCLEGTITCNQKPCPRGPCPE-- 180
C C QNG + Y +G+ ++ +C CRCLEG + C CP C
Sbjct: 634 FCCPECDTRVTSQCLDQNGHKLYRSGDNWT-HSCQQCRCLEGEVDCWPLTCPNLSCEYTA 692
Query: 181 --PGACCPHC---------------KPGCDYEGQLYEEGVTFLSSSNPCLQCTCLRSRVR 223
G CCP C K D G G + + +PC C C RV
Sbjct: 693 ILEGECCPRCVSDPCLADNITYDIRKTCLDSYGVSRLSGSVWTMAGSPCTTCKCKNGRVC 752
Query: 224 C 224
C
Sbjct: 753 C 753
Score = 59.7 bits (143), Expect = 1e-08
Identities = 36/106 (33%), Positives = 47/106 (44%), Gaps = 12/106 (11%)
Query: 683 GDPCRRCLCLDGSVSCQRLPCPPAPCAHPR-----QGPCCPSC-DGCLYQGKEFASGERF 736
GD CR C C G+V C+R+ CPP C+ G CC C C+Y GK A G+R
Sbjct: 289 GDHCRNCTCKSGAVECRRMSCPPLNCSPDSLPVHIAGQCCKVCRPKCIYGGKVLAEGQRI 348
Query: 737 PSPTAACHLC---LCWEGSVSCEPKACAPALCPFPARGDCCPDCDG 779
T +C C + + + C P C+ P CC C G
Sbjct: 349 --LTKSCRECRGGVLVKITEMCPPLNCSEKDHILP-ENQCCRVCRG 391
Score = 54.7 bits (130), Expect = 3e-07
Identities = 45/141 (31%), Positives = 57/141 (40%), Gaps = 21/141 (14%)
Query: 481 DSCTYHSQVYANGQNFTDADSPCHA-----CHCQDGTVTCSLVDCPPTTCARPQSGP--- 532
++C +G + D DS C C+ G V C + CPP C+ P S P
Sbjct: 265 ENCHCEKTCQVSGLLYRDQDSWVDGDHCRNCTCKSGAVECRRMSCPPLNCS-PDSLPVHI 323
Query: 533 -GQCCPRC-PDCILEEEVFVDGESFSHPRDPCQECRCQEGHAHCQPRPCPRAPCA---HP 587
GQCC C P CI +V +G+ C+ECR G CP C+ H
Sbjct: 324 AGQCCKVCRPKCIYGGKVLAEGQRIL--TKSCRECR--GGVLVKITEMCPPLNCSEKDHI 379
Query: 588 LPGTCCPNDCSG---CAFGGK 605
LP C C G CA G K
Sbjct: 380 LPENQCCRVCRGHNFCAEGPK 400
>gi|222352164 nel-like 1 isoform 1 precursor [Homo sapiens]
Length = 810
Score = 131 bits (329), Expect = 3e-30
Identities = 141/549 (25%), Positives = 194/549 (35%), Gaps = 109/549 (19%)
Query: 243 HCCPTCQGCTEGGSHWEHGQEWTTPGDPCRICRCLEGHIQCRQRECASL-CPYPARP--L 299
HC TCQ G + W GD CR C C G ++CR+ C L C + P +
Sbjct: 268 HCEKTCQ---VSGLLYRDQDSWVD-GDHCRNCTCKSGAVECRRMSCPPLNCSPDSLPVHI 323
Query: 300 PGTCCPVC-DGCFLNGREHRSGEPVGSGDPCSHCRCANGSVQCEPLPCPPVPCRHPGKI- 357
G CC VC C G+ G+ + + C CR G + CPP+ C I
Sbjct: 324 AGQCCKVCRPKCIYGGKVLAEGQRILTKS-CRECR--GGVLVKITEMCPPLNCSEKDHIL 380
Query: 358 -PGQCCPVCDGCEYQGHQYQSQETFRLQERGLCVRCSCQAGEVS-------CEE-QECPV 408
QCC VC G + + E + C C++G +S CE+ EC
Sbjct: 381 PENQCCRVCRGHNFCAEGPKCGENSECKNWNTKATCECKSGYISVQGDSAYCEDIDECAA 440
Query: 409 --------TPCA-LPASGRQLCPACELDGEEFA--------EGVQWEPDGRPCT------ 445
T C LP R C + ++F+ G + CT
Sbjct: 441 KMHYCHANTVCVNLPGLYRCDCVPGYIRVDDFSCTEHDECGSGQHNCDENAICTNTVQGH 500
Query: 446 ACVCQDGVPKCGAVLCPPAPCQHPTQPPGAC-------CPS----------CDSCTYHSQ 488
+C C+ G G + A C+ + G C CPS D C+
Sbjct: 501 SCTCKPGYVGNGTIC--RAFCEEGCRYGGTCVAPNKCVCPSGFTGSHCEKDIDECSEGII 558
Query: 489 VYANGQNFTDADSPCHACHCQ-----DGTVTCSLVDC--------------PPTTCARPQ 529
N + H C C+ DGT + S C + C
Sbjct: 559 ECHNHSRCVNLPGWYH-CECRSGFHDDGTYSLSGESCIDIDECALRTHTCWNDSACINLA 617
Query: 530 SGPGQCCPRCP----DCILEEEVFVDGESFSHPRDPCQECRCQEGHAHCQPRPCPRAPCA 585
G CP P DC E + +G+ ++ D C C C++G C+ C C
Sbjct: 618 GGFDCLCPSGPSCSGDCPHEGGLKHNGQVWTLKEDRCSVCSCKDGKIFCRRTACD---CQ 674
Query: 586 HPLPGTCCPNDC-----SGCAF--GGKEYPSGADFPHPSDPCRLCRCLSGNVQCLARRCV 638
+P C +C S C G K Y SG ++ H C+ CRCL G V C C
Sbjct: 675 NPSADLFCCPECDTRVTSQCLDQNGHKLYRSGDNWTHS---CQQCRCLEGEVDCWPLTCP 731
Query: 639 PLPCPEPVLLPGECCPQCPAAPAPAG---------CPRPGAAHARHQEYFSPPGDPCRRC 689
L C +L GECCP+C + P A C ++ G PC C
Sbjct: 732 NLSCEYTAILEGECCPRCVSDPCLADNITYDIRKTCLDSYGVSRLSGSVWTMAGSPCTTC 791
Query: 690 LCLDGSVSC 698
C +G V C
Sbjct: 792 KCKNGRVCC 800
Score = 128 bits (322), Expect = 2e-29
Identities = 140/550 (25%), Positives = 197/550 (35%), Gaps = 126/550 (22%)
Query: 134 HC-RGCSQNGQTYGNGETF-SPDACTTCRCLEGTITCNQKPCPRGPCPEP-------GAC 184
HC + C +G Y + +++ D C C C G + C + CP C G C
Sbjct: 268 HCEKTCQVSGLLYRDQDSWVDGDHCRNCTCKSGAVECRRMSCPPLNCSPDSLPVHIAGQC 327
Query: 185 CPHCKPGCDYEGQLYEEGVTFLSSSNPCLQCTCLRSRVRCMALK-CPPSPCPEP--VLRP 241
C C+P C Y G++ EG L+ S C +C R V + CPP C E +L
Sbjct: 328 CKVCRPKCIYGGKVLAEGQRILTKS--CREC---RGGVLVKITEMCPPLNCSEKDHILPE 382
Query: 242 GHCCPTCQG---CTEGGSHWEHGQ--EWTTPGDPCRICRCLEGHIQCRQ--------REC 288
CC C+G C EG E+ + W T C C G+I + EC
Sbjct: 383 NQCCRVCRGHNFCAEGPKCGENSECKNWNTKA----TCECKSGYISVQGDSAYCEDIDEC 438
Query: 289 ASLCPY-----PARPLPGTCCPVCDGCFLNGREHRSGE--PVGSGD-PCSHCRCANGSVQ 340
A+ Y LPG C ++ + E GSG C +VQ
Sbjct: 439 AAKMHYCHANTVCVNLPGLYRCDCVPGYIRVDDFSCTEHDECGSGQHNCDENAICTNTVQ 498
Query: 341 CEPLPCPP--------------VPCRHPGK--IPGQC-CP---VCDGCEYQGHQYQSQET 380
C P CR+ G P +C CP CE + S+
Sbjct: 499 GHSCTCKPGYVGNGTICRAFCEEGCRYGGTCVAPNKCVCPSGFTGSHCEKDIDEC-SEGI 557
Query: 381 FRLQERGLCV------RCSCQ-----------AGEVSCEEQECPV--------TPCALPA 415
CV C C+ +GE + EC + + C A
Sbjct: 558 IECHNHSRCVNLPGWYHCECRSGFHDDGTYSLSGESCIDIDECALRTHTCWNDSACINLA 617
Query: 416 SGRQ-LCPA-------CELDGEEFAEGVQWEPDGRPCTACVCQDGVPKCGAVLCPPAPCQ 467
G LCP+ C +G G W C+ C C+DG C C CQ
Sbjct: 618 GGFDCLCPSGPSCSGDCPHEGGLKHNGQVWTLKEDRCSVCSCKDGKIFCRRTAC---DCQ 674
Query: 468 HPTQPPGACCPSCDS-----CTYHS--QVYANGQNFTDADSPCHACHCQDGTVTCSLVDC 520
+P+ CCP CD+ C + ++Y +G N+T + C C C +G V C + C
Sbjct: 675 NPSADL-FCCPECDTRVTSQCLDQNGHKLYRSGDNWTHS---CQQCRCLEGEVDCWPLTC 730
Query: 521 PPTTCARPQSGPGQCCPRC-PDCILEEEVFVD---------------GESFSHPRDPCQE 564
P +C G+CCPRC D L + + D G ++ PC
Sbjct: 731 PNLSCEYTAILEGECCPRCVSDPCLADNITYDIRKTCLDSYGVSRLSGSVWTMAGSPCTT 790
Query: 565 CRCQEGHAHC 574
C+C+ G C
Sbjct: 791 CKCKNGRVCC 800
Score = 112 bits (281), Expect = 1e-24
Identities = 140/555 (25%), Positives = 190/555 (34%), Gaps = 136/555 (24%)
Query: 310 CFLNGREHRSGEPVGSGDPCSHCRCANGSVQCEPLPCPPVPCRH---PGKIPGQCCPVC- 365
C ++G +R + GD C +C C +G+V+C + CPP+ C P I GQCC VC
Sbjct: 273 CQVSGLLYRDQDSWVDGDHCRNCTCKSGAVECRRMSCPPLNCSPDSLPVHIAGQCCKVCR 332
Query: 366 DGCEYQGH-----QYQSQETFRLQERGLCVRCSCQAGEVSCEEQE--CPVTPCALPASGR 418
C Y G Q ++ R G+ V+ + ++C E++ P C G
Sbjct: 333 PKCIYGGKVLAEGQRILTKSCRECRGGVLVKITEMCPPLNCSEKDHILPENQCCRVCRGH 392
Query: 419 QLCPACELDGEEFAEGVQWEPDGRPCTACVCQDG-------------VPKCGA------- 458
C GE +E W C C+ G + +C A
Sbjct: 393 NFCAEGPKCGEN-SECKNWNTKA----TCECKSGYISVQGDSAYCEDIDECAAKMHYCHA 447
Query: 459 -VLCPPAPCQHPTQ-PPGACCPSCDSCTYHSQVYANGQNFTDADSPC------HACHCQD 510
+C P + PG SCT H + +GQ+ D ++ C H+C C+
Sbjct: 448 NTVCVNLPGLYRCDCVPGYIRVDDFSCTEHDEC-GSGQHNCDENAICTNTVQGHSCTCKP 506
Query: 511 GTV---TCSLVDCP-----------PTTCARPQSGPGQCCPRCPDCILEEEVFVDGESFS 556
G V T C P C P G C + D E + E +
Sbjct: 507 GYVGNGTICRAFCEEGCRYGGTCVAPNKCVCPSGFTGSHCEKDIDECSEGII----ECHN 562
Query: 557 HPRDPCQECRCQEGHAHCQPRPCPRAPCAHPLPGTCCPNDCSGCAF-------------- 602
H R C G HC+ R + L G C D CA
Sbjct: 563 HSR-----CVNLPGWYHCECRSGFHDDGTYSLSGESCI-DIDECALRTHTCWNDSACINL 616
Query: 603 -GGKEY--PSG----ADFPHPS-------------DPCRLCRCLSGNVQCLARRCVPLPC 642
GG + PSG D PH D C +C C G + C C C
Sbjct: 617 AGGFDCLCPSGPSCSGDCPHEGGLKHNGQVWTLKEDRCSVCSCKDGKIFCRRTAC---DC 673
Query: 643 PEPVLLPGECCPQCPAAPAPAGCPRPGAAHARHQEYFSPPGD----PCRRCLCLDGSVSC 698
P CCP+C + G H+ Y S GD C++C CL+G V C
Sbjct: 674 QNPSA-DLFCCPECDTRVTSQCLDQNG-----HKLYRS--GDNWTHSCQQCRCLEGEVDC 725
Query: 699 QRLPCPPAPCAHPR--QGPCCPSC--DGCLYQ--------------GKEFASGERFPSPT 740
L CP C + +G CCP C D CL G SG +
Sbjct: 726 WPLTCPNLSCEYTAILEGECCPRCVSDPCLADNITYDIRKTCLDSYGVSRLSGSVWTMAG 785
Query: 741 AACHLCLCWEGSVSC 755
+ C C C G V C
Sbjct: 786 SPCTTCKCKNGRVCC 800
Score = 105 bits (261), Expect = 2e-22
Identities = 123/492 (25%), Positives = 159/492 (32%), Gaps = 153/492 (31%)
Query: 424 CELDGEEFAEGVQWEPDGRPCTACVCQDGVPKCGAVLCPPAPCQHPTQP---PGACCPSC 480
C++ G + + W DG C C C+ G +C + CPP C + P G CC C
Sbjct: 273 CQVSGLLYRDQDSWV-DGDHCRNCTCKSGAVECRRMSCPPLNCSPDSLPVHIAGQCCKVC 331
Query: 481 -DSCTYHSQVYANGQNFTDADSPCHACHCQDGTVTCSLVD-CPPTTCARPQS--GPGQCC 536
C Y +V A GQ C C G V + + CPP C+ QCC
Sbjct: 332 RPKCIYGGKVLAEGQRILTKS--CRECR---GGVLVKITEMCPPLNCSEKDHILPENQCC 386
Query: 537 PRC---------PDCILEEE----------------VFVDGES--------------FSH 557
C P C E + V G+S + H
Sbjct: 387 RVCRGHNFCAEGPKCGENSECKNWNTKATCECKSGYISVQGDSAYCEDIDECAAKMHYCH 446
Query: 558 PRDPC------QECRCQEGHAHCQPRPCPR--------------APCAHPLPG------- 590
C C C G+ C A C + + G
Sbjct: 447 ANTVCVNLPGLYRCDCVPGYIRVDDFSCTEHDECGSGQHNCDENAICTNTVQGHSCTCKP 506
Query: 591 ------TCCPNDCS-GCAFGGK-------EYPSGADFPHPSDPCRLCRCLSGNVQCLAR- 635
T C C GC +GG PSG H + C G ++C
Sbjct: 507 GYVGNGTICRAFCEEGCRYGGTCVAPNKCVCPSGFTGSHCEKD--IDECSEGIIECHNHS 564
Query: 636 RCVPLP------CPE------PVLLPGECCPQ---------------------------C 656
RCV LP C L GE C C
Sbjct: 565 RCVNLPGWYHCECRSGFHDDGTYSLSGESCIDIDECALRTHTCWNDSACINLAGGFDCLC 624
Query: 657 PAAPAPAG-CPRPGAAHARHQEYFSPPGDPCRRCLCLDGSVSCQRLPCPPAPCAHPRQGP 715
P+ P+ +G CP G Q + + D C C C DG + C+R C C +P
Sbjct: 625 PSGPSCSGDCPHEGGLKHNGQVW-TLKEDRCSVCSCKDGKIFCRRTACD---CQNPSADL 680
Query: 716 -CCPSCDG-----CLYQG--KEFASGERFPSPTAACHLCLCWEGSVSCEPKACAPALCPF 767
CCP CD CL Q K + SG+ + T +C C C EG V C P C C +
Sbjct: 681 FCCPECDTRVTSQCLDQNGHKLYRSGDNW---THSCQQCRCLEGEVDCWPLTCPNLSCEY 737
Query: 768 PA--RGDCCPDC 777
A G+CCP C
Sbjct: 738 TAILEGECCPRC 749
Score = 101 bits (251), Expect = 3e-21
Identities = 92/334 (27%), Positives = 123/334 (36%), Gaps = 71/334 (21%)
Query: 116 ACVCQDGAAHCGPQAHLPHCRGCSQNGQTYGNGETFSPDACTT--------CR-----CL 162
+C C+ G G CR + G YG G +P+ C C C
Sbjct: 501 SCTCKPGYVGNGTI-----CRAFCEEGCRYG-GTCVAPNKCVCPSGFTGSHCEKDIDECS 554
Query: 163 EGTITC-NQKPCPRGPCPEPGACCPHCKPGCDYEGQLYEEGVTFLSSSNPCLQCTCLRSR 221
EG I C N C PG C+ G +G G + + L+ +
Sbjct: 555 EGIIECHNHSRCVN----LPGWYHCECRSGFHDDGTYSLSGESCIDIDECALRTHTCWND 610
Query: 222 VRCMALK------CPPSPCPEPVLRPGHCCPTCQG-CTEGGSHWEHGQEWTTPGDPCRIC 274
C+ L CP P +C G C G +GQ WT D C +C
Sbjct: 611 SACINLAGGFDCLCPSGP-------------SCSGDCPHEGGLKHNGQVWTLKEDRCSVC 657
Query: 275 RCLEGHIQCRQRECASLCPYPARPLPGTCCPVCDGCFLNGREHRSGEPV-GSGD----PC 329
C +G I CR+ C C P+ L CCP CD + ++G + SGD C
Sbjct: 658 SCKDGKIFCRRTACD--CQNPSADL--FCCPECDTRVTSQCLDQNGHKLYRSGDNWTHSC 713
Query: 330 SHCRCANGSVQCEPLPCPPVPCRHPGKIPGQCCPVC--DGCEYQGHQYQSQETFRLQERG 387
CRC G V C PL CP + C + + G+CCP C D C Y ++T L G
Sbjct: 714 QQCRCLEGEVDCWPLTCPNLSCEYTAILEGECCPRCVSDPCLADNITYDIRKTC-LDSYG 772
Query: 388 L--------------CVRCSCQAGEVSCE-EQEC 406
+ C C C+ G V C + EC
Sbjct: 773 VSRLSGSVWTMAGSPCTTCKCKNGRVCCSVDFEC 806
Score = 89.7 bits (221), Expect = 1e-17
Identities = 134/576 (23%), Positives = 193/576 (33%), Gaps = 167/576 (28%)
Query: 78 QTRVRQLESCECHPASPQCWGLGRAWPEGARW-EPDACTACVCQDGAA----------HC 126
+TR+ QLE+C C C G + + W + D C C C+ GA +C
Sbjct: 258 ETRLSQLENCHCEKT---CQVSGLLYRDQDSWVDGDHCRNCTCKSGAVECRRMSCPPLNC 314
Query: 127 GPQAHLPHCRG---------CSQNGQTYGNGETFSPDACTTCRCLEGTITCNQKPCPRGP 177
P + H G C G+ G+ +C CR G + + CP
Sbjct: 315 SPDSLPVHIAGQCCKVCRPKCIYGGKVLAEGQRILTKSCRECR--GGVLVKITEMCPPLN 372
Query: 178 CPEP------GACC------------PHC-----------KPGCDYE-GQLYEEG----- 202
C E CC P C K C+ + G + +G
Sbjct: 373 CSEKDHILPENQCCRVCRGHNFCAEGPKCGENSECKNWNTKATCECKSGYISVQGDSAYC 432
Query: 203 ---------VTFLSSSNPCL------QCTCLRSRVRCMALKCPPSP--------CPEPVL 239
+ + ++ C+ +C C+ +R C C E +
Sbjct: 433 EDIDECAAKMHYCHANTVCVNLPGLYRCDCVPGYIRVDDFSCTEHDECGSGQHNCDENAI 492
Query: 240 RP----GHCCPTC----------------QGCTEGGSHWEHGQEWTTP----GDPCR--I 273
GH C TC +GC GG+ + P G C I
Sbjct: 493 CTNTVQGHSC-TCKPGYVGNGTICRAFCEEGCRYGGT-CVAPNKCVCPSGFTGSHCEKDI 550
Query: 274 CRCLEGHIQCRQRE-CASLCPYPARPLPGTC-CPVCDGCFLNGREHRSGEPVGSGDPCS- 330
C EG I+C C +L PG C G +G SGE D C+
Sbjct: 551 DECSEGIIECHNHSRCVNL--------PGWYHCECRSGFHDDGTYSLSGESCIDIDECAL 602
Query: 331 --HCRCANGSVQCEPLPCPPVPCRHPGKIPGQCCPVCDG-CEYQGHQYQSQETFRLQERG 387
H C N S C L C P P C G C ++G + + + L+E
Sbjct: 603 RTHT-CWNDSA-CINL-AGGFDCLCPSG------PSCSGDCPHEGGLKHNGQVWTLKE-D 652
Query: 388 LCVRCSCQAGEVSCEEQECPVTPCALPASGRQLCPACEL---------DGEE-FAEGVQW 437
C CSC+ G++ C C C P++ CP C+ +G + + G W
Sbjct: 653 RCSVCSCKDGKIFCRRTACD---CQNPSADLFCCPECDTRVTSQCLDQNGHKLYRSGDNW 709
Query: 438 EPDGRPCTACVCQDGVPKCGAVLCPPAPCQHPTQPPGACCPSC--DSCTYHSQVY----- 490
C C C +G C + CP C++ G CCP C D C + Y
Sbjct: 710 T---HSCQQCRCLEGEVDCWPLTCPNLSCEYTAILEGECCPRCVSDPCLADNITYDIRKT 766
Query: 491 ---------ANGQNFTDADSPCHACHCQDGTVTCSL 517
+G +T A SPC C C++G V CS+
Sbjct: 767 CLDSYGVSRLSGSVWTMAGSPCTTCKCKNGRVCCSV 802
Score = 59.7 bits (143), Expect = 1e-08
Identities = 36/106 (33%), Positives = 47/106 (44%), Gaps = 12/106 (11%)
Query: 683 GDPCRRCLCLDGSVSCQRLPCPPAPCAHPR-----QGPCCPSC-DGCLYQGKEFASGERF 736
GD CR C C G+V C+R+ CPP C+ G CC C C+Y GK A G+R
Sbjct: 289 GDHCRNCTCKSGAVECRRMSCPPLNCSPDSLPVHIAGQCCKVCRPKCIYGGKVLAEGQRI 348
Query: 737 PSPTAACHLC---LCWEGSVSCEPKACAPALCPFPARGDCCPDCDG 779
T +C C + + + C P C+ P CC C G
Sbjct: 349 --LTKSCRECRGGVLVKITEMCPPLNCSEKDHILP-ENQCCRVCRG 391
Score = 54.7 bits (130), Expect = 3e-07
Identities = 45/141 (31%), Positives = 57/141 (40%), Gaps = 21/141 (14%)
Query: 481 DSCTYHSQVYANGQNFTDADSPCHA-----CHCQDGTVTCSLVDCPPTTCARPQSGP--- 532
++C +G + D DS C C+ G V C + CPP C+ P S P
Sbjct: 265 ENCHCEKTCQVSGLLYRDQDSWVDGDHCRNCTCKSGAVECRRMSCPPLNCS-PDSLPVHI 323
Query: 533 -GQCCPRC-PDCILEEEVFVDGESFSHPRDPCQECRCQEGHAHCQPRPCPRAPCA---HP 587
GQCC C P CI +V +G+ C+ECR G CP C+ H
Sbjct: 324 AGQCCKVCRPKCIYGGKVLAEGQRIL--TKSCRECR--GGVLVKITEMCPPLNCSEKDHI 379
Query: 588 LPGTCCPNDCSG---CAFGGK 605
LP C C G CA G K
Sbjct: 380 LPENQCCRVCRGHNFCAEGPK 400
>gi|223029476 NEL-like protein 2 isoform d [Homo sapiens]
Length = 839
Score = 127 bits (320), Expect = 3e-29
Identities = 137/561 (24%), Positives = 185/561 (32%), Gaps = 140/561 (24%)
Query: 136 RGCSQNGQTYGNGETFSPDACTTCRCLEGTITCNQKPCPRGPCP-------EPGACCPHC 188
R C+ G TY E++ D C C CL GTI C CP CP G CC C
Sbjct: 295 RTCTMKGTTYREFESWI-DGCKNCTCLNGTIQCETLICPNPDCPLKSALAYVDGKCCKEC 353
Query: 189 KPGCDYEGQLYEEGV--TFLSSSNPCLQCTCLRSRVRCMALK-CPPSPCPEP--VLRPGH 243
K C ++G+ Y EG T SSS C+ C ++ + CP CPE +
Sbjct: 354 KSICQFQGRTYFEGERNTVYSSSGVCVLYECKDQTMKLVESSGCPALDCPESHQITLSHS 413
Query: 244 CCPTCQG---CTEGGSHWEHGQEWTTPGDPCRICR------------------CLEGHIQ 282
CC C+G C+E + E+ CR C EG
Sbjct: 414 CCKVCKGYDFCSERHNCMENSICRNLNDRAVCSCRDGFRALREDNAYCEDIDECAEGRHY 473
Query: 283 CRQRE-CAS-------LCPYPARPLPGTCCPVCDGCFLNGREHRSGEPV----------- 323
CR+ C + +C + C D C N +H E
Sbjct: 474 CRENTMCVNTPGSFMCICKTGYIRIDDYSCTEHDECITN--QHNCDENALCFNTVGGHNC 531
Query: 324 -------GSGDPC-SHCR--CANGS--VQCEPLPCPPVPCRHPGKIPGQCCPVCDGCEYQ 371
G+G C + C+ C NG + CP G C D C
Sbjct: 532 VCKPGYTGNGTTCKAFCKDGCRNGGACIAANVCACPQ------GFTGPSCETDIDEC--- 582
Query: 372 GHQYQSQETFRLQERGLCVR------CSCQAGE----------VSCEE-QECPVT----- 409
S + R C+ C C+ G SCE+ EC
Sbjct: 583 -----SDGFVQCDSRANCINLPGWYHCECRDGYHDNGMFSPSGESCEDIDECGTGRHSCA 637
Query: 410 ------------PCALPASGRQLCPACELDGEEFAEGVQWEPDGRPCTACVCQDGVPKCG 457
C P G+ C DG+ G W + C+ C CQ+G C
Sbjct: 638 NDTICFNLDGGYDCRCP-HGKNCTGDCIHDGKVKHNGQIWVLENDRCSVCSCQNGFVMCR 696
Query: 458 AVLCPPAPCQHPTQPPGACCPSCDSCTYHSQVYANGQNFTDADSP----CHACHCQDGTV 513
++C C++PT CCP CD ++ NG+ ++ C C C G V
Sbjct: 697 RMVCD---CENPTVDL-FCCPECDPRLSSQCLHQNGETLYNSGDTWVQNCQQCRCLQGEV 752
Query: 514 TCSLVDCPPTTCARPQSGPGQCCPRC---------------PDCILEEEVF-VDGESFSH 557
C + CP C +CCPRC C+ E V G S+
Sbjct: 753 DCWPLPCPDVECEFSILPENECCPRCVTDPCQADTIRNDITKTCLDEMNVVRFTGSSWIK 812
Query: 558 PRDPCQECRCQEGHAHCQPRP 578
C C+C+ GH C P
Sbjct: 813 HGTECTLCQCKNGHICCSVDP 833
Score = 115 bits (288), Expect = 2e-25
Identities = 132/547 (24%), Positives = 185/547 (33%), Gaps = 113/547 (20%)
Query: 251 CTEGGSHWEHGQEWTTPGDPCRICRCLEGHIQCRQRECASLCPYPARPLP-------GTC 303
CT G+ + + W D C+ C CL G IQC +CP P PL G C
Sbjct: 297 CTMKGTTYREFESWI---DGCKNCTCLNGTIQCE----TLICPNPDCPLKSALAYVDGKC 349
Query: 304 CPVCDG-CFLNGREHRSGEP---VGSGDPCSHCRCANGSVQC-EPLPCPPVPC--RHPGK 356
C C C GR + GE S C C + +++ E CP + C H
Sbjct: 350 CKECKSICQFQGRTYFEGERNTVYSSSGVCVLYECKDQTMKLVESSGCPALDCPESHQIT 409
Query: 357 IPGQCCPVCDGCEYQGHQYQSQETFRLQERGLCVRCSCQAG-------EVSCEE-QECPV 408
+ CC VC G ++ ++ E + CSC+ G CE+ EC
Sbjct: 410 LSHSCCKVCKGYDFCSERHNCMENSICRNLNDRAVCSCRDGFRALREDNAYCEDIDECAE 469
Query: 409 --------TPCA-LPASGRQLCPA--CELDGEEFAEGVQWEPDGRPCTA----------- 446
T C P S +C +D E + + C
Sbjct: 470 GRHYCRENTMCVNTPGSFMCICKTGYIRIDDYSCTEHDECITNQHNCDENALCFNTVGGH 529
Query: 447 -CVCQDGVPKCGAVLCPPAPCQHPTQPPGAC-------CP---SCDSCTYHSQVYANGQN 495
CVC+ G G A C+ + GAC CP + SC ++G
Sbjct: 530 NCVCKPGYTGNGTTC--KAFCKDGCRNGGACIAANVCACPQGFTGPSCETDIDECSDGFV 587
Query: 496 FTDADSPC------HACHCQDGT----------VTCSLVD--------CPPTTCARPQSG 531
D+ + C + C C+DG +C +D C T G
Sbjct: 588 QCDSRANCINLPGWYHCECRDGYHDNGMFSPSGESCEDIDECGTGRHSCANDTICFNLDG 647
Query: 532 PGQCCPRCP-------DCILEEEVFVDGESFSHPRDPCQECRCQEGHAHCQPRPCPRAPC 584
C RCP DCI + +V +G+ + D C C CQ G C+ C C
Sbjct: 648 GYDC--RCPHGKNCTGDCIHDGKVKHNGQIWVLENDRCSVCSCQNGFVMCRRMVCD---C 702
Query: 585 AHPLPGTCCPNDCSGCAFGGKEYPSGADFPHPSDP----CRLCRCLSGNVQCLARRCVPL 640
+P C +C + +G + D C+ CRCL G V C C +
Sbjct: 703 ENPTVDLFCCPECDPRLSSQCLHQNGETLYNSGDTWVQNCQQCRCLQGEVDCWPLPCPDV 762
Query: 641 PCPEPVLLPGECCPQCPAAPAPAGCPRPGAAHARHQEY---------FSPPGDPCRRCLC 691
C +L ECCP+C P A R E + G C C C
Sbjct: 763 ECEFSILPENECCPRCVTDPCQADTIRNDITKTCLDEMNVVRFTGSSWIKHGTECTLCQC 822
Query: 692 LDGSVSC 698
+G + C
Sbjct: 823 KNGHICC 829
Score = 104 bits (259), Expect = 4e-22
Identities = 136/553 (24%), Positives = 185/553 (33%), Gaps = 127/553 (22%)
Query: 310 CFLNGREHRSGEPVGSGDPCSHCRCANGSVQCEPLPCPPVPCRHPGK---IPGQCCPVCD 366
C + G +R E G C +C C NG++QCE L CP C + G+CC C
Sbjct: 297 CTMKGTTYREFESWIDG--CKNCTCLNGTIQCETLICPNPDCPLKSALAYVDGKCCKECK 354
Query: 367 G-CEYQGHQY-QSQETFRLQERGLCVRCSCQAGEVSCEEQE-CPVTPCALPAS-----GR 418
C++QG Y + + G+CV C+ + E CP C P S
Sbjct: 355 SICQFQGRTYFEGERNTVYSSSGVCVLYECKDQTMKLVESSGCPALDC--PESHQITLSH 412
Query: 419 QLCPACELDGEEFAEGVQWEPDGRPC------TACVCQDGVPKCGA--VLCPPAP----- 465
C C+ G +F + C C C+DG C
Sbjct: 413 SCCKVCK--GYDFCSERHNCMENSICRNLNDRAVCSCRDGFRALREDNAYCEDIDECAEG 470
Query: 466 ---CQHPTQ---PPGACCPSCD---------SCTYHSQVYANGQNFTDADSPC------H 504
C+ T PG+ C SCT H + N N D ++ C H
Sbjct: 471 RHYCRENTMCVNTPGSFMCICKTGYIRIDDYSCTEHDECITNQHN-CDENALCFNTVGGH 529
Query: 505 ACHCQDGTV----TCSLV---DC-------PPTTCARPQSGPGQCCPRCPDCILEEEVFV 550
C C+ G TC C CA PQ G C D + V
Sbjct: 530 NCVCKPGYTGNGTTCKAFCKDGCRNGGACIAANVCACPQGFTGPSCETDIDECSDGFVQC 589
Query: 551 DGESFSHPRDPCQECRCQEGH----------AHCQP--------RPCPRAPCAHPLPG-- 590
D + C C++G+ C+ C L G
Sbjct: 590 DSRANCINLPGWYHCECRDGYHDNGMFSPSGESCEDIDECGTGRHSCANDTICFNLDGGY 649
Query: 591 TC-CPN--DCSG-CAFGGKEYPSGADFPHPSDPCRLCRCLSGNVQCLARRCVPLPCPEPV 646
C CP+ +C+G C GK +G + +D C +C C +G V C C C P
Sbjct: 650 DCRCPHGKNCTGDCIHDGKVKHNGQIWVLENDRCSVCSCQNGFVMCRRMVC---DCENPT 706
Query: 647 LLPGECCPQCPAAPAPAGCPRPGAAHARHQ--EYFSPPGDP----CRRCLCLDGSVSCQR 700
+ CCP+C PR ++ HQ E GD C++C CL G V C
Sbjct: 707 V-DLFCCPECD--------PRL-SSQCLHQNGETLYNSGDTWVQNCQQCRCLQGEVDCWP 756
Query: 701 LPCPPAPCAHP--RQGPCCPSC---------------DGCLYQGKEFA-SGERFPSPTAA 742
LPCP C + CCP C CL + +G +
Sbjct: 757 LPCPDVECEFSILPENECCPRCVTDPCQADTIRNDITKTCLDEMNVVRFTGSSWIKHGTE 816
Query: 743 CHLCLCWEGSVSC 755
C LC C G + C
Sbjct: 817 CTLCQCKNGHICC 829
Score = 92.4 bits (228), Expect = 1e-18
Identities = 88/321 (27%), Positives = 114/321 (35%), Gaps = 58/321 (18%)
Query: 117 CVCQDGAAHCGPQAHLPHCRGCSQNGQTYGNG-----ETFSPDACTTC--RCLEGTITCN 169
CVC+ G G GC G + F+ +C T C +G + C+
Sbjct: 531 CVCKPGYTGNGTTCKAFCKDGCRNGGACIAANVCACPQGFTGPSCETDIDECSDGFVQCD 590
Query: 170 QKPCPRGPCPE-PGACCPHCKPGCDYEGQLYEEGVTFLSSSNPCLQCT-CLRSRVRCMAL 227
R C PG C+ G Y + F S C C R C
Sbjct: 591 S----RANCINLPGWYHCECRDG-------YHDNGMFSPSGESCEDIDECGTGRHSC--- 636
Query: 228 KCPPSPCPEPVLRPGHCC-----PTCQG-CTEGGSHWEHGQEWTTPGDPCRICRCLEGHI 281
+ C L G+ C C G C G +GQ W D C +C C G +
Sbjct: 637 -ANDTICFN--LDGGYDCRCPHGKNCTGDCIHDGKVKHNGQIWVLENDRCSVCSCQNGFV 693
Query: 282 QCRQRECASLCPYPARPLPGTCCPVCDGCFLNGREHRSGEPV-GSGDP----CSHCRCAN 336
CR+ C C P L CCP CD + H++GE + SGD C CRC
Sbjct: 694 MCRRMVCD--CENPTVDL--FCCPECDPRLSSQCLHQNGETLYNSGDTWVQNCQQCRCLQ 749
Query: 337 GSVQCEPLPCPPVPCRHPGKIPGQCCPVC--DGCEYQGHQYQSQETFRLQERGL------ 388
G V C PLPCP V C +CCP C D C+ + +T L E +
Sbjct: 750 GEVDCWPLPCPDVECEFSILPENECCPRCVTDPCQADTIRNDITKTC-LDEMNVVRFTGS 808
Query: 389 --------CVRCSCQAGEVSC 401
C C C+ G + C
Sbjct: 809 SWIKHGTECTLCQCKNGHICC 829
Score = 83.2 bits (204), Expect = 9e-16
Identities = 117/494 (23%), Positives = 161/494 (32%), Gaps = 152/494 (30%)
Query: 424 CELDGEEFAEGVQWEPDGRPCTACVCQDGVPKCGAVLCPPAPCQHPTQ---PPGACCPSC 480
C + G + E W DG C C C +G +C ++CP C + G CC C
Sbjct: 297 CTMKGTTYREFESWI-DG--CKNCTCLNGTIQCETLICPNPDCPLKSALAYVDGKCCKEC 353
Query: 481 DS-CTYHSQVYANGQNFT--DADSPCHACHCQDGTVT------CSLVDCPPT-------T 524
S C + + Y G+ T + C C+D T+ C +DCP + +
Sbjct: 354 KSICQFQGRTYFEGERNTVYSSSGVCVLYECKDQTMKLVESSGCPALDCPESHQITLSHS 413
Query: 525 CARPQSGPGQCCPR-------------------CPD---CILEEEVFV-DGESFSHPRDP 561
C + G C R C D + E+ + D + + R
Sbjct: 414 CCKVCKGYDFCSERHNCMENSICRNLNDRAVCSCRDGFRALREDNAYCEDIDECAEGRHY 473
Query: 562 CQE------------CRCQEGHAHCQPRPCPR--------------APCAHPLPG----- 590
C+E C C+ G+ C A C + + G
Sbjct: 474 CRENTMCVNTPGSFMCICKTGYIRIDDYSCTEHDECITNQHNCDENALCFNTVGGHNCVC 533
Query: 591 --------TCCPNDCS-GCAFGGK-------EYPSGADFPHPSDPCRLCRCLSGNVQCLA 634
T C C GC GG P G F PS + C G VQC +
Sbjct: 534 KPGYTGNGTTCKAFCKDGCRNGGACIAANVCACPQG--FTGPSCETDIDECSDGFVQCDS 591
Query: 635 R-RCVPLP------CPEP-----VLLP-GECCP--------------------------- 654
R C+ LP C + + P GE C
Sbjct: 592 RANCINLPGWYHCECRDGYHDNGMFSPSGESCEDIDECGTGRHSCANDTICFNLDGGYDC 651
Query: 655 QCPAAPAPAG-CPRPGAAHARHQEYFSPPGDPCRRCLCLDGSVSCQRLPCPPAPCAHPRQ 713
+CP G C G Q + D C C C +G V C+R+ C C +P
Sbjct: 652 RCPHGKNCTGDCIHDGKVKHNGQIWVLE-NDRCSVCSCQNGFVMCRRMVCD---CENPTV 707
Query: 714 GP-CCPSCDG-----CLYQGKE--FASGERFPSPTAACHLCLCWEGSVSCEPKACAPALC 765
CCP CD CL+Q E + SG+ + C C C +G V C P C C
Sbjct: 708 DLFCCPECDPRLSSQCLHQNGETLYNSGDTW---VQNCQQCRCLQGEVDCWPLPCPDVEC 764
Query: 766 PFP--ARGDCCPDC 777
F +CCP C
Sbjct: 765 EFSILPENECCPRC 778
Score = 77.0 bits (188), Expect = 6e-14
Identities = 68/261 (26%), Positives = 97/261 (37%), Gaps = 43/261 (16%)
Query: 119 CQDGAAHCGPQAH---LP---HCR---GCSQNGQTYGNGETFSP-DACTTCR--CLEGTI 166
C DG C +A+ LP HC G NG +GE+ D C T R C TI
Sbjct: 582 CSDGFVQCDSRANCINLPGWYHCECRDGYHDNGMFSPSGESCEDIDECGTGRHSCANDTI 641
Query: 167 TCNQKPCPRGPCPEPGACCPHCKPGCDYEGQLYEEGVTFLSSSNPCLQCTCLRSRVRCMA 226
N CP +C C ++G++ G ++ ++ C C+C V C
Sbjct: 642 CFNLDGGYDCRCPHG----KNCTGDCIHDGKVKHNGQIWVLENDRCSVCSCQNGFVMCRR 697
Query: 227 LKCPPSPCPEPVLRPGHCCPTCQGCTEGGSHWEHGQEWTTPGDP----CRICRCLEGHIQ 282
+ C C P + CCP C ++G+ GD C+ CRCL+G +
Sbjct: 698 MVCD---CENPTVDL-FCCPECDPRLSSQCLHQNGETLYNSGDTWVQNCQQCRCLQGEVD 753
Query: 283 CRQRECASL-CPYPARPLPGTCCPVC--DGCF---------------LNGREHRSGEPVG 324
C C + C + P CCP C D C +N +
Sbjct: 754 CWPLPCPDVECEFSILP-ENECCPRCVTDPCQADTIRNDITKTCLDEMNVVRFTGSSWIK 812
Query: 325 SGDPCSHCRCANGSVQCEPLP 345
G C+ C+C NG + C P
Sbjct: 813 HGTECTLCQCKNGHICCSVDP 833
Score = 63.5 bits (153), Expect = 7e-10
Identities = 48/176 (27%), Positives = 68/176 (38%), Gaps = 39/176 (22%)
Query: 665 CPRPGAAHARHQEYFSPPGDPCRRCLCLDGSVSCQRLPCPPAPCAHPR-----QGPCCPS 719
C G + + + D C+ C CL+G++ C+ L CP C G CC
Sbjct: 297 CTMKGTTYREFESWI----DGCKNCTCLNGTIQCETLICPNPDCPLKSALAYVDGKCCKE 352
Query: 720 CDG-CLYQGKEFASGER--FPSPTAACHLCLCWEGSVSCEPKACAPAL-CP----FPARG 771
C C +QG+ + GER S + C L C + ++ + PAL CP
Sbjct: 353 CKSICQFQGRTYFEGERNTVYSSSGVCVLYECKDQTMKLVESSGCPALDCPESHQITLSH 412
Query: 772 DCCPDCDG-----EGH--------------GIGSCRGGMRETRGLGQNNLYCPRVD 808
CC C G E H + SCR G R R ++N YC +D
Sbjct: 413 SCCKVCKGYDFCSERHNCMENSICRNLNDRAVCSCRDGFRALR---EDNAYCEDID 465
Score = 62.4 bits (150), Expect = 2e-09
Identities = 62/227 (27%), Positives = 80/227 (35%), Gaps = 78/227 (34%)
Query: 87 CECHPASPQCWGL----GRAWPEGARW--EPDACTACVCQDGAAHC--------GPQAHL 132
C C P C G G+ G W E D C+ C CQ+G C P L
Sbjct: 651 CRC-PHGKNCTGDCIHDGKVKHNGQIWVLENDRCSVCSCQNGFVMCRRMVCDCENPTVDL 709
Query: 133 PHCRGCS---------QNGQT-YGNGETFSPDACTTCRCLEGTITCNQKPCPRGPC---- 178
C C QNG+T Y +G+T+ + C CRCL+G + C PCP C
Sbjct: 710 FCCPECDPRLSSQCLHQNGETLYNSGDTWVQN-CQQCRCLQGEVDCWPLPCPDVECEFSI 768
Query: 179 -PEPGACCPHCKPGCDYEGQLYEEGVTFLSSSNPCLQCTCLRSRVRCMALKCPPSPCPEP 237
PE CCP C ++PC Q +R+ +
Sbjct: 769 LPE-NECCPRC-------------------VTDPC-QADTIRNDI--------------- 792
Query: 238 VLRPGHCCPTCQGCTEGGSHW-EHGQEWTTPGDPCRICRCLEGHIQC 283
C GS W +HG E C +C+C GHI C
Sbjct: 793 ---TKTCLDEMNVVRFTGSSWIKHGTE-------CTLCQCKNGHICC 829
>gi|223029474 NEL-like protein 2 isoform c [Homo sapiens]
Length = 815
Score = 127 bits (320), Expect = 3e-29
Identities = 137/561 (24%), Positives = 185/561 (32%), Gaps = 140/561 (24%)
Query: 136 RGCSQNGQTYGNGETFSPDACTTCRCLEGTITCNQKPCPRGPCP-------EPGACCPHC 188
R C+ G TY E++ D C C CL GTI C CP CP G CC C
Sbjct: 271 RTCTMKGTTYREFESWI-DGCKNCTCLNGTIQCETLICPNPDCPLKSALAYVDGKCCKEC 329
Query: 189 KPGCDYEGQLYEEGV--TFLSSSNPCLQCTCLRSRVRCMALK-CPPSPCPEP--VLRPGH 243
K C ++G+ Y EG T SSS C+ C ++ + CP CPE +
Sbjct: 330 KSICQFQGRTYFEGERNTVYSSSGVCVLYECKDQTMKLVESSGCPALDCPESHQITLSHS 389
Query: 244 CCPTCQG---CTEGGSHWEHGQEWTTPGDPCRICR------------------CLEGHIQ 282
CC C+G C+E + E+ CR C EG
Sbjct: 390 CCKVCKGYDFCSERHNCMENSICRNLNDRAVCSCRDGFRALREDNAYCEDIDECAEGRHY 449
Query: 283 CRQRE-CAS-------LCPYPARPLPGTCCPVCDGCFLNGREHRSGEPV----------- 323
CR+ C + +C + C D C N +H E
Sbjct: 450 CRENTMCVNTPGSFMCICKTGYIRIDDYSCTEHDECITN--QHNCDENALCFNTVGGHNC 507
Query: 324 -------GSGDPC-SHCR--CANGS--VQCEPLPCPPVPCRHPGKIPGQCCPVCDGCEYQ 371
G+G C + C+ C NG + CP G C D C
Sbjct: 508 VCKPGYTGNGTTCKAFCKDGCRNGGACIAANVCACPQ------GFTGPSCETDIDEC--- 558
Query: 372 GHQYQSQETFRLQERGLCVR------CSCQAGE----------VSCEE-QECPVT----- 409
S + R C+ C C+ G SCE+ EC
Sbjct: 559 -----SDGFVQCDSRANCINLPGWYHCECRDGYHDNGMFSPSGESCEDIDECGTGRHSCA 613
Query: 410 ------------PCALPASGRQLCPACELDGEEFAEGVQWEPDGRPCTACVCQDGVPKCG 457
C P G+ C DG+ G W + C+ C CQ+G C
Sbjct: 614 NDTICFNLDGGYDCRCP-HGKNCTGDCIHDGKVKHNGQIWVLENDRCSVCSCQNGFVMCR 672
Query: 458 AVLCPPAPCQHPTQPPGACCPSCDSCTYHSQVYANGQNFTDADSP----CHACHCQDGTV 513
++C C++PT CCP CD ++ NG+ ++ C C C G V
Sbjct: 673 RMVCD---CENPTVDL-FCCPECDPRLSSQCLHQNGETLYNSGDTWVQNCQQCRCLQGEV 728
Query: 514 TCSLVDCPPTTCARPQSGPGQCCPRC---------------PDCILEEEVF-VDGESFSH 557
C + CP C +CCPRC C+ E V G S+
Sbjct: 729 DCWPLPCPDVECEFSILPENECCPRCVTDPCQADTIRNDITKTCLDEMNVVRFTGSSWIK 788
Query: 558 PRDPCQECRCQEGHAHCQPRP 578
C C+C+ GH C P
Sbjct: 789 HGTECTLCQCKNGHICCSVDP 809
Score = 115 bits (288), Expect = 2e-25
Identities = 132/547 (24%), Positives = 185/547 (33%), Gaps = 113/547 (20%)
Query: 251 CTEGGSHWEHGQEWTTPGDPCRICRCLEGHIQCRQRECASLCPYPARPLP-------GTC 303
CT G+ + + W D C+ C CL G IQC +CP P PL G C
Sbjct: 273 CTMKGTTYREFESWI---DGCKNCTCLNGTIQCE----TLICPNPDCPLKSALAYVDGKC 325
Query: 304 CPVCDG-CFLNGREHRSGEP---VGSGDPCSHCRCANGSVQC-EPLPCPPVPC--RHPGK 356
C C C GR + GE S C C + +++ E CP + C H
Sbjct: 326 CKECKSICQFQGRTYFEGERNTVYSSSGVCVLYECKDQTMKLVESSGCPALDCPESHQIT 385
Query: 357 IPGQCCPVCDGCEYQGHQYQSQETFRLQERGLCVRCSCQAG-------EVSCEE-QECPV 408
+ CC VC G ++ ++ E + CSC+ G CE+ EC
Sbjct: 386 LSHSCCKVCKGYDFCSERHNCMENSICRNLNDRAVCSCRDGFRALREDNAYCEDIDECAE 445
Query: 409 --------TPCA-LPASGRQLCPA--CELDGEEFAEGVQWEPDGRPCTA----------- 446
T C P S +C +D E + + C
Sbjct: 446 GRHYCRENTMCVNTPGSFMCICKTGYIRIDDYSCTEHDECITNQHNCDENALCFNTVGGH 505
Query: 447 -CVCQDGVPKCGAVLCPPAPCQHPTQPPGAC-------CP---SCDSCTYHSQVYANGQN 495
CVC+ G G A C+ + GAC CP + SC ++G
Sbjct: 506 NCVCKPGYTGNGTTC--KAFCKDGCRNGGACIAANVCACPQGFTGPSCETDIDECSDGFV 563
Query: 496 FTDADSPC------HACHCQDGT----------VTCSLVD--------CPPTTCARPQSG 531
D+ + C + C C+DG +C +D C T G
Sbjct: 564 QCDSRANCINLPGWYHCECRDGYHDNGMFSPSGESCEDIDECGTGRHSCANDTICFNLDG 623
Query: 532 PGQCCPRCP-------DCILEEEVFVDGESFSHPRDPCQECRCQEGHAHCQPRPCPRAPC 584
C RCP DCI + +V +G+ + D C C CQ G C+ C C
Sbjct: 624 GYDC--RCPHGKNCTGDCIHDGKVKHNGQIWVLENDRCSVCSCQNGFVMCRRMVCD---C 678
Query: 585 AHPLPGTCCPNDCSGCAFGGKEYPSGADFPHPSDP----CRLCRCLSGNVQCLARRCVPL 640
+P C +C + +G + D C+ CRCL G V C C +
Sbjct: 679 ENPTVDLFCCPECDPRLSSQCLHQNGETLYNSGDTWVQNCQQCRCLQGEVDCWPLPCPDV 738
Query: 641 PCPEPVLLPGECCPQCPAAPAPAGCPRPGAAHARHQEY---------FSPPGDPCRRCLC 691
C +L ECCP+C P A R E + G C C C
Sbjct: 739 ECEFSILPENECCPRCVTDPCQADTIRNDITKTCLDEMNVVRFTGSSWIKHGTECTLCQC 798
Query: 692 LDGSVSC 698
+G + C
Sbjct: 799 KNGHICC 805
Score = 104 bits (259), Expect = 4e-22
Identities = 136/553 (24%), Positives = 185/553 (33%), Gaps = 127/553 (22%)
Query: 310 CFLNGREHRSGEPVGSGDPCSHCRCANGSVQCEPLPCPPVPCRHPGK---IPGQCCPVCD 366
C + G +R E G C +C C NG++QCE L CP C + G+CC C
Sbjct: 273 CTMKGTTYREFESWIDG--CKNCTCLNGTIQCETLICPNPDCPLKSALAYVDGKCCKECK 330
Query: 367 G-CEYQGHQY-QSQETFRLQERGLCVRCSCQAGEVSCEEQE-CPVTPCALPAS-----GR 418
C++QG Y + + G+CV C+ + E CP C P S
Sbjct: 331 SICQFQGRTYFEGERNTVYSSSGVCVLYECKDQTMKLVESSGCPALDC--PESHQITLSH 388
Query: 419 QLCPACELDGEEFAEGVQWEPDGRPC------TACVCQDGVPKCGA--VLCPPAP----- 465
C C+ G +F + C C C+DG C
Sbjct: 389 SCCKVCK--GYDFCSERHNCMENSICRNLNDRAVCSCRDGFRALREDNAYCEDIDECAEG 446
Query: 466 ---CQHPTQ---PPGACCPSCD---------SCTYHSQVYANGQNFTDADSPC------H 504
C+ T PG+ C SCT H + N N D ++ C H
Sbjct: 447 RHYCRENTMCVNTPGSFMCICKTGYIRIDDYSCTEHDECITNQHN-CDENALCFNTVGGH 505
Query: 505 ACHCQDGTV----TCSLV---DC-------PPTTCARPQSGPGQCCPRCPDCILEEEVFV 550
C C+ G TC C CA PQ G C D + V
Sbjct: 506 NCVCKPGYTGNGTTCKAFCKDGCRNGGACIAANVCACPQGFTGPSCETDIDECSDGFVQC 565
Query: 551 DGESFSHPRDPCQECRCQEGH----------AHCQP--------RPCPRAPCAHPLPG-- 590
D + C C++G+ C+ C L G
Sbjct: 566 DSRANCINLPGWYHCECRDGYHDNGMFSPSGESCEDIDECGTGRHSCANDTICFNLDGGY 625
Query: 591 TC-CPN--DCSG-CAFGGKEYPSGADFPHPSDPCRLCRCLSGNVQCLARRCVPLPCPEPV 646
C CP+ +C+G C GK +G + +D C +C C +G V C C C P
Sbjct: 626 DCRCPHGKNCTGDCIHDGKVKHNGQIWVLENDRCSVCSCQNGFVMCRRMVC---DCENPT 682
Query: 647 LLPGECCPQCPAAPAPAGCPRPGAAHARHQ--EYFSPPGDP----CRRCLCLDGSVSCQR 700
+ CCP+C PR ++ HQ E GD C++C CL G V C
Sbjct: 683 V-DLFCCPECD--------PRL-SSQCLHQNGETLYNSGDTWVQNCQQCRCLQGEVDCWP 732
Query: 701 LPCPPAPCAHP--RQGPCCPSC---------------DGCLYQGKEFA-SGERFPSPTAA 742
LPCP C + CCP C CL + +G +
Sbjct: 733 LPCPDVECEFSILPENECCPRCVTDPCQADTIRNDITKTCLDEMNVVRFTGSSWIKHGTE 792
Query: 743 CHLCLCWEGSVSC 755
C LC C G + C
Sbjct: 793 CTLCQCKNGHICC 805
Score = 92.4 bits (228), Expect = 1e-18
Identities = 88/321 (27%), Positives = 114/321 (35%), Gaps = 58/321 (18%)
Query: 117 CVCQDGAAHCGPQAHLPHCRGCSQNGQTYGNG-----ETFSPDACTTC--RCLEGTITCN 169
CVC+ G G GC G + F+ +C T C +G + C+
Sbjct: 507 CVCKPGYTGNGTTCKAFCKDGCRNGGACIAANVCACPQGFTGPSCETDIDECSDGFVQCD 566
Query: 170 QKPCPRGPCPE-PGACCPHCKPGCDYEGQLYEEGVTFLSSSNPCLQCT-CLRSRVRCMAL 227
R C PG C+ G Y + F S C C R C
Sbjct: 567 S----RANCINLPGWYHCECRDG-------YHDNGMFSPSGESCEDIDECGTGRHSC--- 612
Query: 228 KCPPSPCPEPVLRPGHCC-----PTCQG-CTEGGSHWEHGQEWTTPGDPCRICRCLEGHI 281
+ C L G+ C C G C G +GQ W D C +C C G +
Sbjct: 613 -ANDTICFN--LDGGYDCRCPHGKNCTGDCIHDGKVKHNGQIWVLENDRCSVCSCQNGFV 669
Query: 282 QCRQRECASLCPYPARPLPGTCCPVCDGCFLNGREHRSGEPV-GSGDP----CSHCRCAN 336
CR+ C C P L CCP CD + H++GE + SGD C CRC
Sbjct: 670 MCRRMVCD--CENPTVDL--FCCPECDPRLSSQCLHQNGETLYNSGDTWVQNCQQCRCLQ 725
Query: 337 GSVQCEPLPCPPVPCRHPGKIPGQCCPVC--DGCEYQGHQYQSQETFRLQERGL------ 388
G V C PLPCP V C +CCP C D C+ + +T L E +
Sbjct: 726 GEVDCWPLPCPDVECEFSILPENECCPRCVTDPCQADTIRNDITKTC-LDEMNVVRFTGS 784
Query: 389 --------CVRCSCQAGEVSC 401
C C C+ G + C
Sbjct: 785 SWIKHGTECTLCQCKNGHICC 805
Score = 83.2 bits (204), Expect = 9e-16
Identities = 117/494 (23%), Positives = 161/494 (32%), Gaps = 152/494 (30%)
Query: 424 CELDGEEFAEGVQWEPDGRPCTACVCQDGVPKCGAVLCPPAPCQHPTQ---PPGACCPSC 480
C + G + E W DG C C C +G +C ++CP C + G CC C
Sbjct: 273 CTMKGTTYREFESWI-DG--CKNCTCLNGTIQCETLICPNPDCPLKSALAYVDGKCCKEC 329
Query: 481 DS-CTYHSQVYANGQNFT--DADSPCHACHCQDGTVT------CSLVDCPPT-------T 524
S C + + Y G+ T + C C+D T+ C +DCP + +
Sbjct: 330 KSICQFQGRTYFEGERNTVYSSSGVCVLYECKDQTMKLVESSGCPALDCPESHQITLSHS 389
Query: 525 CARPQSGPGQCCPR-------------------CPD---CILEEEVFV-DGESFSHPRDP 561
C + G C R C D + E+ + D + + R
Sbjct: 390 CCKVCKGYDFCSERHNCMENSICRNLNDRAVCSCRDGFRALREDNAYCEDIDECAEGRHY 449
Query: 562 CQE------------CRCQEGHAHCQPRPCPR--------------APCAHPLPG----- 590
C+E C C+ G+ C A C + + G
Sbjct: 450 CRENTMCVNTPGSFMCICKTGYIRIDDYSCTEHDECITNQHNCDENALCFNTVGGHNCVC 509
Query: 591 --------TCCPNDCS-GCAFGGK-------EYPSGADFPHPSDPCRLCRCLSGNVQCLA 634
T C C GC GG P G F PS + C G VQC +
Sbjct: 510 KPGYTGNGTTCKAFCKDGCRNGGACIAANVCACPQG--FTGPSCETDIDECSDGFVQCDS 567
Query: 635 R-RCVPLP------CPEP-----VLLP-GECCP--------------------------- 654
R C+ LP C + + P GE C
Sbjct: 568 RANCINLPGWYHCECRDGYHDNGMFSPSGESCEDIDECGTGRHSCANDTICFNLDGGYDC 627
Query: 655 QCPAAPAPAG-CPRPGAAHARHQEYFSPPGDPCRRCLCLDGSVSCQRLPCPPAPCAHPRQ 713
+CP G C G Q + D C C C +G V C+R+ C C +P
Sbjct: 628 RCPHGKNCTGDCIHDGKVKHNGQIWVLE-NDRCSVCSCQNGFVMCRRMVCD---CENPTV 683
Query: 714 GP-CCPSCDG-----CLYQGKE--FASGERFPSPTAACHLCLCWEGSVSCEPKACAPALC 765
CCP CD CL+Q E + SG+ + C C C +G V C P C C
Sbjct: 684 DLFCCPECDPRLSSQCLHQNGETLYNSGDTW---VQNCQQCRCLQGEVDCWPLPCPDVEC 740
Query: 766 PFP--ARGDCCPDC 777
F +CCP C
Sbjct: 741 EFSILPENECCPRC 754
Score = 77.0 bits (188), Expect = 6e-14
Identities = 68/261 (26%), Positives = 97/261 (37%), Gaps = 43/261 (16%)
Query: 119 CQDGAAHCGPQAH---LP---HCR---GCSQNGQTYGNGETFSP-DACTTCR--CLEGTI 166
C DG C +A+ LP HC G NG +GE+ D C T R C TI
Sbjct: 558 CSDGFVQCDSRANCINLPGWYHCECRDGYHDNGMFSPSGESCEDIDECGTGRHSCANDTI 617
Query: 167 TCNQKPCPRGPCPEPGACCPHCKPGCDYEGQLYEEGVTFLSSSNPCLQCTCLRSRVRCMA 226
N CP +C C ++G++ G ++ ++ C C+C V C
Sbjct: 618 CFNLDGGYDCRCPHG----KNCTGDCIHDGKVKHNGQIWVLENDRCSVCSCQNGFVMCRR 673
Query: 227 LKCPPSPCPEPVLRPGHCCPTCQGCTEGGSHWEHGQEWTTPGDP----CRICRCLEGHIQ 282
+ C C P + CCP C ++G+ GD C+ CRCL+G +
Sbjct: 674 MVCD---CENPTVDL-FCCPECDPRLSSQCLHQNGETLYNSGDTWVQNCQQCRCLQGEVD 729
Query: 283 CRQRECASL-CPYPARPLPGTCCPVC--DGCF---------------LNGREHRSGEPVG 324
C C + C + P CCP C D C +N +
Sbjct: 730 CWPLPCPDVECEFSILP-ENECCPRCVTDPCQADTIRNDITKTCLDEMNVVRFTGSSWIK 788
Query: 325 SGDPCSHCRCANGSVQCEPLP 345
G C+ C+C NG + C P
Sbjct: 789 HGTECTLCQCKNGHICCSVDP 809
Score = 63.5 bits (153), Expect = 7e-10
Identities = 48/176 (27%), Positives = 68/176 (38%), Gaps = 39/176 (22%)
Query: 665 CPRPGAAHARHQEYFSPPGDPCRRCLCLDGSVSCQRLPCPPAPCAHPR-----QGPCCPS 719
C G + + + D C+ C CL+G++ C+ L CP C G CC
Sbjct: 273 CTMKGTTYREFESWI----DGCKNCTCLNGTIQCETLICPNPDCPLKSALAYVDGKCCKE 328
Query: 720 CDG-CLYQGKEFASGER--FPSPTAACHLCLCWEGSVSCEPKACAPAL-CP----FPARG 771
C C +QG+ + GER S + C L C + ++ + PAL CP
Sbjct: 329 CKSICQFQGRTYFEGERNTVYSSSGVCVLYECKDQTMKLVESSGCPALDCPESHQITLSH 388
Query: 772 DCCPDCDG-----EGH--------------GIGSCRGGMRETRGLGQNNLYCPRVD 808
CC C G E H + SCR G R R ++N YC +D
Sbjct: 389 SCCKVCKGYDFCSERHNCMENSICRNLNDRAVCSCRDGFRALR---EDNAYCEDID 441
Score = 62.4 bits (150), Expect = 2e-09
Identities = 62/227 (27%), Positives = 80/227 (35%), Gaps = 78/227 (34%)
Query: 87 CECHPASPQCWGL----GRAWPEGARW--EPDACTACVCQDGAAHC--------GPQAHL 132
C C P C G G+ G W E D C+ C CQ+G C P L
Sbjct: 627 CRC-PHGKNCTGDCIHDGKVKHNGQIWVLENDRCSVCSCQNGFVMCRRMVCDCENPTVDL 685
Query: 133 PHCRGCS---------QNGQT-YGNGETFSPDACTTCRCLEGTITCNQKPCPRGPC---- 178
C C QNG+T Y +G+T+ + C CRCL+G + C PCP C
Sbjct: 686 FCCPECDPRLSSQCLHQNGETLYNSGDTWVQN-CQQCRCLQGEVDCWPLPCPDVECEFSI 744
Query: 179 -PEPGACCPHCKPGCDYEGQLYEEGVTFLSSSNPCLQCTCLRSRVRCMALKCPPSPCPEP 237
PE CCP C ++PC Q +R+ +
Sbjct: 745 LPE-NECCPRC-------------------VTDPC-QADTIRNDI--------------- 768
Query: 238 VLRPGHCCPTCQGCTEGGSHW-EHGQEWTTPGDPCRICRCLEGHIQC 283
C GS W +HG E C +C+C GHI C
Sbjct: 769 ---TKTCLDEMNVVRFTGSSWIKHGTE-------CTLCQCKNGHICC 805
>gi|223029472 NEL-like protein 2 isoform b precursor [Homo sapiens]
Length = 816
Score = 127 bits (320), Expect = 3e-29
Identities = 137/561 (24%), Positives = 185/561 (32%), Gaps = 140/561 (24%)
Query: 136 RGCSQNGQTYGNGETFSPDACTTCRCLEGTITCNQKPCPRGPCP-------EPGACCPHC 188
R C+ G TY E++ D C C CL GTI C CP CP G CC C
Sbjct: 272 RTCTMKGTTYREFESWI-DGCKNCTCLNGTIQCETLICPNPDCPLKSALAYVDGKCCKEC 330
Query: 189 KPGCDYEGQLYEEGV--TFLSSSNPCLQCTCLRSRVRCMALK-CPPSPCPEP--VLRPGH 243
K C ++G+ Y EG T SSS C+ C ++ + CP CPE +
Sbjct: 331 KSICQFQGRTYFEGERNTVYSSSGVCVLYECKDQTMKLVESSGCPALDCPESHQITLSHS 390
Query: 244 CCPTCQG---CTEGGSHWEHGQEWTTPGDPCRICR------------------CLEGHIQ 282
CC C+G C+E + E+ CR C EG
Sbjct: 391 CCKVCKGYDFCSERHNCMENSICRNLNDRAVCSCRDGFRALREDNAYCEDIDECAEGRHY 450
Query: 283 CRQRE-CAS-------LCPYPARPLPGTCCPVCDGCFLNGREHRSGEPV----------- 323
CR+ C + +C + C D C N +H E
Sbjct: 451 CRENTMCVNTPGSFMCICKTGYIRIDDYSCTEHDECITN--QHNCDENALCFNTVGGHNC 508
Query: 324 -------GSGDPC-SHCR--CANGS--VQCEPLPCPPVPCRHPGKIPGQCCPVCDGCEYQ 371
G+G C + C+ C NG + CP G C D C
Sbjct: 509 VCKPGYTGNGTTCKAFCKDGCRNGGACIAANVCACPQ------GFTGPSCETDIDEC--- 559
Query: 372 GHQYQSQETFRLQERGLCVR------CSCQAGE----------VSCEE-QECPVT----- 409
S + R C+ C C+ G SCE+ EC
Sbjct: 560 -----SDGFVQCDSRANCINLPGWYHCECRDGYHDNGMFSPSGESCEDIDECGTGRHSCA 614
Query: 410 ------------PCALPASGRQLCPACELDGEEFAEGVQWEPDGRPCTACVCQDGVPKCG 457
C P G+ C DG+ G W + C+ C CQ+G C
Sbjct: 615 NDTICFNLDGGYDCRCP-HGKNCTGDCIHDGKVKHNGQIWVLENDRCSVCSCQNGFVMCR 673
Query: 458 AVLCPPAPCQHPTQPPGACCPSCDSCTYHSQVYANGQNFTDADSP----CHACHCQDGTV 513
++C C++PT CCP CD ++ NG+ ++ C C C G V
Sbjct: 674 RMVCD---CENPTVDL-FCCPECDPRLSSQCLHQNGETLYNSGDTWVQNCQQCRCLQGEV 729
Query: 514 TCSLVDCPPTTCARPQSGPGQCCPRC---------------PDCILEEEVF-VDGESFSH 557
C + CP C +CCPRC C+ E V G S+
Sbjct: 730 DCWPLPCPDVECEFSILPENECCPRCVTDPCQADTIRNDITKTCLDEMNVVRFTGSSWIK 789
Query: 558 PRDPCQECRCQEGHAHCQPRP 578
C C+C+ GH C P
Sbjct: 790 HGTECTLCQCKNGHICCSVDP 810
Score = 115 bits (288), Expect = 2e-25
Identities = 132/547 (24%), Positives = 185/547 (33%), Gaps = 113/547 (20%)
Query: 251 CTEGGSHWEHGQEWTTPGDPCRICRCLEGHIQCRQRECASLCPYPARPLP-------GTC 303
CT G+ + + W D C+ C CL G IQC +CP P PL G C
Sbjct: 274 CTMKGTTYREFESWI---DGCKNCTCLNGTIQCE----TLICPNPDCPLKSALAYVDGKC 326
Query: 304 CPVCDG-CFLNGREHRSGEP---VGSGDPCSHCRCANGSVQC-EPLPCPPVPC--RHPGK 356
C C C GR + GE S C C + +++ E CP + C H
Sbjct: 327 CKECKSICQFQGRTYFEGERNTVYSSSGVCVLYECKDQTMKLVESSGCPALDCPESHQIT 386
Query: 357 IPGQCCPVCDGCEYQGHQYQSQETFRLQERGLCVRCSCQAG-------EVSCEE-QECPV 408
+ CC VC G ++ ++ E + CSC+ G CE+ EC
Sbjct: 387 LSHSCCKVCKGYDFCSERHNCMENSICRNLNDRAVCSCRDGFRALREDNAYCEDIDECAE 446
Query: 409 --------TPCA-LPASGRQLCPA--CELDGEEFAEGVQWEPDGRPCTA----------- 446
T C P S +C +D E + + C
Sbjct: 447 GRHYCRENTMCVNTPGSFMCICKTGYIRIDDYSCTEHDECITNQHNCDENALCFNTVGGH 506
Query: 447 -CVCQDGVPKCGAVLCPPAPCQHPTQPPGAC-------CP---SCDSCTYHSQVYANGQN 495
CVC+ G G A C+ + GAC CP + SC ++G
Sbjct: 507 NCVCKPGYTGNGTTC--KAFCKDGCRNGGACIAANVCACPQGFTGPSCETDIDECSDGFV 564
Query: 496 FTDADSPC------HACHCQDGT----------VTCSLVD--------CPPTTCARPQSG 531
D+ + C + C C+DG +C +D C T G
Sbjct: 565 QCDSRANCINLPGWYHCECRDGYHDNGMFSPSGESCEDIDECGTGRHSCANDTICFNLDG 624
Query: 532 PGQCCPRCP-------DCILEEEVFVDGESFSHPRDPCQECRCQEGHAHCQPRPCPRAPC 584
C RCP DCI + +V +G+ + D C C CQ G C+ C C
Sbjct: 625 GYDC--RCPHGKNCTGDCIHDGKVKHNGQIWVLENDRCSVCSCQNGFVMCRRMVCD---C 679
Query: 585 AHPLPGTCCPNDCSGCAFGGKEYPSGADFPHPSDP----CRLCRCLSGNVQCLARRCVPL 640
+P C +C + +G + D C+ CRCL G V C C +
Sbjct: 680 ENPTVDLFCCPECDPRLSSQCLHQNGETLYNSGDTWVQNCQQCRCLQGEVDCWPLPCPDV 739
Query: 641 PCPEPVLLPGECCPQCPAAPAPAGCPRPGAAHARHQEY---------FSPPGDPCRRCLC 691
C +L ECCP+C P A R E + G C C C
Sbjct: 740 ECEFSILPENECCPRCVTDPCQADTIRNDITKTCLDEMNVVRFTGSSWIKHGTECTLCQC 799
Query: 692 LDGSVSC 698
+G + C
Sbjct: 800 KNGHICC 806
Score = 104 bits (259), Expect = 4e-22
Identities = 136/553 (24%), Positives = 185/553 (33%), Gaps = 127/553 (22%)
Query: 310 CFLNGREHRSGEPVGSGDPCSHCRCANGSVQCEPLPCPPVPCRHPGK---IPGQCCPVCD 366
C + G +R E G C +C C NG++QCE L CP C + G+CC C
Sbjct: 274 CTMKGTTYREFESWIDG--CKNCTCLNGTIQCETLICPNPDCPLKSALAYVDGKCCKECK 331
Query: 367 G-CEYQGHQY-QSQETFRLQERGLCVRCSCQAGEVSCEEQE-CPVTPCALPAS-----GR 418
C++QG Y + + G+CV C+ + E CP C P S
Sbjct: 332 SICQFQGRTYFEGERNTVYSSSGVCVLYECKDQTMKLVESSGCPALDC--PESHQITLSH 389
Query: 419 QLCPACELDGEEFAEGVQWEPDGRPC------TACVCQDGVPKCGA--VLCPPAP----- 465
C C+ G +F + C C C+DG C
Sbjct: 390 SCCKVCK--GYDFCSERHNCMENSICRNLNDRAVCSCRDGFRALREDNAYCEDIDECAEG 447
Query: 466 ---CQHPTQ---PPGACCPSCD---------SCTYHSQVYANGQNFTDADSPC------H 504
C+ T PG+ C SCT H + N N D ++ C H
Sbjct: 448 RHYCRENTMCVNTPGSFMCICKTGYIRIDDYSCTEHDECITNQHN-CDENALCFNTVGGH 506
Query: 505 ACHCQDGTV----TCSLV---DC-------PPTTCARPQSGPGQCCPRCPDCILEEEVFV 550
C C+ G TC C CA PQ G C D + V
Sbjct: 507 NCVCKPGYTGNGTTCKAFCKDGCRNGGACIAANVCACPQGFTGPSCETDIDECSDGFVQC 566
Query: 551 DGESFSHPRDPCQECRCQEGH----------AHCQP--------RPCPRAPCAHPLPG-- 590
D + C C++G+ C+ C L G
Sbjct: 567 DSRANCINLPGWYHCECRDGYHDNGMFSPSGESCEDIDECGTGRHSCANDTICFNLDGGY 626
Query: 591 TC-CPN--DCSG-CAFGGKEYPSGADFPHPSDPCRLCRCLSGNVQCLARRCVPLPCPEPV 646
C CP+ +C+G C GK +G + +D C +C C +G V C C C P
Sbjct: 627 DCRCPHGKNCTGDCIHDGKVKHNGQIWVLENDRCSVCSCQNGFVMCRRMVC---DCENPT 683
Query: 647 LLPGECCPQCPAAPAPAGCPRPGAAHARHQ--EYFSPPGDP----CRRCLCLDGSVSCQR 700
+ CCP+C PR ++ HQ E GD C++C CL G V C
Sbjct: 684 V-DLFCCPECD--------PRL-SSQCLHQNGETLYNSGDTWVQNCQQCRCLQGEVDCWP 733
Query: 701 LPCPPAPCAHP--RQGPCCPSC---------------DGCLYQGKEFA-SGERFPSPTAA 742
LPCP C + CCP C CL + +G +
Sbjct: 734 LPCPDVECEFSILPENECCPRCVTDPCQADTIRNDITKTCLDEMNVVRFTGSSWIKHGTE 793
Query: 743 CHLCLCWEGSVSC 755
C LC C G + C
Sbjct: 794 CTLCQCKNGHICC 806
Score = 92.4 bits (228), Expect = 1e-18
Identities = 88/321 (27%), Positives = 114/321 (35%), Gaps = 58/321 (18%)
Query: 117 CVCQDGAAHCGPQAHLPHCRGCSQNGQTYGNG-----ETFSPDACTTC--RCLEGTITCN 169
CVC+ G G GC G + F+ +C T C +G + C+
Sbjct: 508 CVCKPGYTGNGTTCKAFCKDGCRNGGACIAANVCACPQGFTGPSCETDIDECSDGFVQCD 567
Query: 170 QKPCPRGPCPE-PGACCPHCKPGCDYEGQLYEEGVTFLSSSNPCLQCT-CLRSRVRCMAL 227
R C PG C+ G Y + F S C C R C
Sbjct: 568 S----RANCINLPGWYHCECRDG-------YHDNGMFSPSGESCEDIDECGTGRHSC--- 613
Query: 228 KCPPSPCPEPVLRPGHCC-----PTCQG-CTEGGSHWEHGQEWTTPGDPCRICRCLEGHI 281
+ C L G+ C C G C G +GQ W D C +C C G +
Sbjct: 614 -ANDTICFN--LDGGYDCRCPHGKNCTGDCIHDGKVKHNGQIWVLENDRCSVCSCQNGFV 670
Query: 282 QCRQRECASLCPYPARPLPGTCCPVCDGCFLNGREHRSGEPV-GSGDP----CSHCRCAN 336
CR+ C C P L CCP CD + H++GE + SGD C CRC
Sbjct: 671 MCRRMVCD--CENPTVDL--FCCPECDPRLSSQCLHQNGETLYNSGDTWVQNCQQCRCLQ 726
Query: 337 GSVQCEPLPCPPVPCRHPGKIPGQCCPVC--DGCEYQGHQYQSQETFRLQERGL------ 388
G V C PLPCP V C +CCP C D C+ + +T L E +
Sbjct: 727 GEVDCWPLPCPDVECEFSILPENECCPRCVTDPCQADTIRNDITKTC-LDEMNVVRFTGS 785
Query: 389 --------CVRCSCQAGEVSC 401
C C C+ G + C
Sbjct: 786 SWIKHGTECTLCQCKNGHICC 806
Score = 83.2 bits (204), Expect = 9e-16
Identities = 117/494 (23%), Positives = 161/494 (32%), Gaps = 152/494 (30%)
Query: 424 CELDGEEFAEGVQWEPDGRPCTACVCQDGVPKCGAVLCPPAPCQHPTQ---PPGACCPSC 480
C + G + E W DG C C C +G +C ++CP C + G CC C
Sbjct: 274 CTMKGTTYREFESWI-DG--CKNCTCLNGTIQCETLICPNPDCPLKSALAYVDGKCCKEC 330
Query: 481 DS-CTYHSQVYANGQNFT--DADSPCHACHCQDGTVT------CSLVDCPPT-------T 524
S C + + Y G+ T + C C+D T+ C +DCP + +
Sbjct: 331 KSICQFQGRTYFEGERNTVYSSSGVCVLYECKDQTMKLVESSGCPALDCPESHQITLSHS 390
Query: 525 CARPQSGPGQCCPR-------------------CPD---CILEEEVFV-DGESFSHPRDP 561
C + G C R C D + E+ + D + + R
Sbjct: 391 CCKVCKGYDFCSERHNCMENSICRNLNDRAVCSCRDGFRALREDNAYCEDIDECAEGRHY 450
Query: 562 CQE------------CRCQEGHAHCQPRPCPR--------------APCAHPLPG----- 590
C+E C C+ G+ C A C + + G
Sbjct: 451 CRENTMCVNTPGSFMCICKTGYIRIDDYSCTEHDECITNQHNCDENALCFNTVGGHNCVC 510
Query: 591 --------TCCPNDCS-GCAFGGK-------EYPSGADFPHPSDPCRLCRCLSGNVQCLA 634
T C C GC GG P G F PS + C G VQC +
Sbjct: 511 KPGYTGNGTTCKAFCKDGCRNGGACIAANVCACPQG--FTGPSCETDIDECSDGFVQCDS 568
Query: 635 R-RCVPLP------CPEP-----VLLP-GECCP--------------------------- 654
R C+ LP C + + P GE C
Sbjct: 569 RANCINLPGWYHCECRDGYHDNGMFSPSGESCEDIDECGTGRHSCANDTICFNLDGGYDC 628
Query: 655 QCPAAPAPAG-CPRPGAAHARHQEYFSPPGDPCRRCLCLDGSVSCQRLPCPPAPCAHPRQ 713
+CP G C G Q + D C C C +G V C+R+ C C +P
Sbjct: 629 RCPHGKNCTGDCIHDGKVKHNGQIWVLE-NDRCSVCSCQNGFVMCRRMVCD---CENPTV 684
Query: 714 GP-CCPSCDG-----CLYQGKE--FASGERFPSPTAACHLCLCWEGSVSCEPKACAPALC 765
CCP CD CL+Q E + SG+ + C C C +G V C P C C
Sbjct: 685 DLFCCPECDPRLSSQCLHQNGETLYNSGDTW---VQNCQQCRCLQGEVDCWPLPCPDVEC 741
Query: 766 PFP--ARGDCCPDC 777
F +CCP C
Sbjct: 742 EFSILPENECCPRC 755
Score = 77.0 bits (188), Expect = 6e-14
Identities = 68/261 (26%), Positives = 97/261 (37%), Gaps = 43/261 (16%)
Query: 119 CQDGAAHCGPQAH---LP---HCR---GCSQNGQTYGNGETFSP-DACTTCR--CLEGTI 166
C DG C +A+ LP HC G NG +GE+ D C T R C TI
Sbjct: 559 CSDGFVQCDSRANCINLPGWYHCECRDGYHDNGMFSPSGESCEDIDECGTGRHSCANDTI 618
Query: 167 TCNQKPCPRGPCPEPGACCPHCKPGCDYEGQLYEEGVTFLSSSNPCLQCTCLRSRVRCMA 226
N CP +C C ++G++ G ++ ++ C C+C V C
Sbjct: 619 CFNLDGGYDCRCPHG----KNCTGDCIHDGKVKHNGQIWVLENDRCSVCSCQNGFVMCRR 674
Query: 227 LKCPPSPCPEPVLRPGHCCPTCQGCTEGGSHWEHGQEWTTPGDP----CRICRCLEGHIQ 282
+ C C P + CCP C ++G+ GD C+ CRCL+G +
Sbjct: 675 MVCD---CENPTVDL-FCCPECDPRLSSQCLHQNGETLYNSGDTWVQNCQQCRCLQGEVD 730
Query: 283 CRQRECASL-CPYPARPLPGTCCPVC--DGCF---------------LNGREHRSGEPVG 324
C C + C + P CCP C D C +N +
Sbjct: 731 CWPLPCPDVECEFSILP-ENECCPRCVTDPCQADTIRNDITKTCLDEMNVVRFTGSSWIK 789
Query: 325 SGDPCSHCRCANGSVQCEPLP 345
G C+ C+C NG + C P
Sbjct: 790 HGTECTLCQCKNGHICCSVDP 810
Score = 63.5 bits (153), Expect = 7e-10
Identities = 48/176 (27%), Positives = 68/176 (38%), Gaps = 39/176 (22%)
Query: 665 CPRPGAAHARHQEYFSPPGDPCRRCLCLDGSVSCQRLPCPPAPCAHPR-----QGPCCPS 719
C G + + + D C+ C CL+G++ C+ L CP C G CC
Sbjct: 274 CTMKGTTYREFESWI----DGCKNCTCLNGTIQCETLICPNPDCPLKSALAYVDGKCCKE 329
Query: 720 CDG-CLYQGKEFASGER--FPSPTAACHLCLCWEGSVSCEPKACAPAL-CP----FPARG 771
C C +QG+ + GER S + C L C + ++ + PAL CP
Sbjct: 330 CKSICQFQGRTYFEGERNTVYSSSGVCVLYECKDQTMKLVESSGCPALDCPESHQITLSH 389
Query: 772 DCCPDCDG-----EGH--------------GIGSCRGGMRETRGLGQNNLYCPRVD 808
CC C G E H + SCR G R R ++N YC +D
Sbjct: 390 SCCKVCKGYDFCSERHNCMENSICRNLNDRAVCSCRDGFRALR---EDNAYCEDID 442
Score = 62.4 bits (150), Expect = 2e-09
Identities = 62/227 (27%), Positives = 80/227 (35%), Gaps = 78/227 (34%)
Query: 87 CECHPASPQCWGL----GRAWPEGARW--EPDACTACVCQDGAAHC--------GPQAHL 132
C C P C G G+ G W E D C+ C CQ+G C P L
Sbjct: 628 CRC-PHGKNCTGDCIHDGKVKHNGQIWVLENDRCSVCSCQNGFVMCRRMVCDCENPTVDL 686
Query: 133 PHCRGCS---------QNGQT-YGNGETFSPDACTTCRCLEGTITCNQKPCPRGPC---- 178
C C QNG+T Y +G+T+ + C CRCL+G + C PCP C
Sbjct: 687 FCCPECDPRLSSQCLHQNGETLYNSGDTWVQN-CQQCRCLQGEVDCWPLPCPDVECEFSI 745
Query: 179 -PEPGACCPHCKPGCDYEGQLYEEGVTFLSSSNPCLQCTCLRSRVRCMALKCPPSPCPEP 237
PE CCP C ++PC Q +R+ +
Sbjct: 746 LPE-NECCPRC-------------------VTDPC-QADTIRNDI--------------- 769
Query: 238 VLRPGHCCPTCQGCTEGGSHW-EHGQEWTTPGDPCRICRCLEGHIQC 283
C GS W +HG E C +C+C GHI C
Sbjct: 770 ---TKTCLDEMNVVRFTGSSWIKHGTE-------CTLCQCKNGHICC 806
>gi|223029470 NEL-like protein 2 isoform a [Homo sapiens]
Length = 866
Score = 127 bits (320), Expect = 3e-29
Identities = 137/561 (24%), Positives = 185/561 (32%), Gaps = 140/561 (24%)
Query: 136 RGCSQNGQTYGNGETFSPDACTTCRCLEGTITCNQKPCPRGPCP-------EPGACCPHC 188
R C+ G TY E++ D C C CL GTI C CP CP G CC C
Sbjct: 322 RTCTMKGTTYREFESWI-DGCKNCTCLNGTIQCETLICPNPDCPLKSALAYVDGKCCKEC 380
Query: 189 KPGCDYEGQLYEEGV--TFLSSSNPCLQCTCLRSRVRCMALK-CPPSPCPEP--VLRPGH 243
K C ++G+ Y EG T SSS C+ C ++ + CP CPE +
Sbjct: 381 KSICQFQGRTYFEGERNTVYSSSGVCVLYECKDQTMKLVESSGCPALDCPESHQITLSHS 440
Query: 244 CCPTCQG---CTEGGSHWEHGQEWTTPGDPCRICR------------------CLEGHIQ 282
CC C+G C+E + E+ CR C EG
Sbjct: 441 CCKVCKGYDFCSERHNCMENSICRNLNDRAVCSCRDGFRALREDNAYCEDIDECAEGRHY 500
Query: 283 CRQRE-CAS-------LCPYPARPLPGTCCPVCDGCFLNGREHRSGEPV----------- 323
CR+ C + +C + C D C N +H E
Sbjct: 501 CRENTMCVNTPGSFMCICKTGYIRIDDYSCTEHDECITN--QHNCDENALCFNTVGGHNC 558
Query: 324 -------GSGDPC-SHCR--CANGS--VQCEPLPCPPVPCRHPGKIPGQCCPVCDGCEYQ 371
G+G C + C+ C NG + CP G C D C
Sbjct: 559 VCKPGYTGNGTTCKAFCKDGCRNGGACIAANVCACPQ------GFTGPSCETDIDEC--- 609
Query: 372 GHQYQSQETFRLQERGLCVR------CSCQAGE----------VSCEE-QECPVT----- 409
S + R C+ C C+ G SCE+ EC
Sbjct: 610 -----SDGFVQCDSRANCINLPGWYHCECRDGYHDNGMFSPSGESCEDIDECGTGRHSCA 664
Query: 410 ------------PCALPASGRQLCPACELDGEEFAEGVQWEPDGRPCTACVCQDGVPKCG 457
C P G+ C DG+ G W + C+ C CQ+G C
Sbjct: 665 NDTICFNLDGGYDCRCP-HGKNCTGDCIHDGKVKHNGQIWVLENDRCSVCSCQNGFVMCR 723
Query: 458 AVLCPPAPCQHPTQPPGACCPSCDSCTYHSQVYANGQNFTDADSP----CHACHCQDGTV 513
++C C++PT CCP CD ++ NG+ ++ C C C G V
Sbjct: 724 RMVCD---CENPTVDL-FCCPECDPRLSSQCLHQNGETLYNSGDTWVQNCQQCRCLQGEV 779
Query: 514 TCSLVDCPPTTCARPQSGPGQCCPRC---------------PDCILEEEVF-VDGESFSH 557
C + CP C +CCPRC C+ E V G S+
Sbjct: 780 DCWPLPCPDVECEFSILPENECCPRCVTDPCQADTIRNDITKTCLDEMNVVRFTGSSWIK 839
Query: 558 PRDPCQECRCQEGHAHCQPRP 578
C C+C+ GH C P
Sbjct: 840 HGTECTLCQCKNGHICCSVDP 860
Score = 115 bits (288), Expect = 2e-25
Identities = 132/547 (24%), Positives = 185/547 (33%), Gaps = 113/547 (20%)
Query: 251 CTEGGSHWEHGQEWTTPGDPCRICRCLEGHIQCRQRECASLCPYPARPLP-------GTC 303
CT G+ + + W D C+ C CL G IQC +CP P PL G C
Sbjct: 324 CTMKGTTYREFESWI---DGCKNCTCLNGTIQCE----TLICPNPDCPLKSALAYVDGKC 376
Query: 304 CPVCDG-CFLNGREHRSGEP---VGSGDPCSHCRCANGSVQC-EPLPCPPVPC--RHPGK 356
C C C GR + GE S C C + +++ E CP + C H
Sbjct: 377 CKECKSICQFQGRTYFEGERNTVYSSSGVCVLYECKDQTMKLVESSGCPALDCPESHQIT 436
Query: 357 IPGQCCPVCDGCEYQGHQYQSQETFRLQERGLCVRCSCQAG-------EVSCEE-QECPV 408
+ CC VC G ++ ++ E + CSC+ G CE+ EC
Sbjct: 437 LSHSCCKVCKGYDFCSERHNCMENSICRNLNDRAVCSCRDGFRALREDNAYCEDIDECAE 496
Query: 409 --------TPCA-LPASGRQLCPA--CELDGEEFAEGVQWEPDGRPCTA----------- 446
T C P S +C +D E + + C
Sbjct: 497 GRHYCRENTMCVNTPGSFMCICKTGYIRIDDYSCTEHDECITNQHNCDENALCFNTVGGH 556
Query: 447 -CVCQDGVPKCGAVLCPPAPCQHPTQPPGAC-------CP---SCDSCTYHSQVYANGQN 495
CVC+ G G A C+ + GAC CP + SC ++G
Sbjct: 557 NCVCKPGYTGNGTTC--KAFCKDGCRNGGACIAANVCACPQGFTGPSCETDIDECSDGFV 614
Query: 496 FTDADSPC------HACHCQDGT----------VTCSLVD--------CPPTTCARPQSG 531
D+ + C + C C+DG +C +D C T G
Sbjct: 615 QCDSRANCINLPGWYHCECRDGYHDNGMFSPSGESCEDIDECGTGRHSCANDTICFNLDG 674
Query: 532 PGQCCPRCP-------DCILEEEVFVDGESFSHPRDPCQECRCQEGHAHCQPRPCPRAPC 584
C RCP DCI + +V +G+ + D C C CQ G C+ C C
Sbjct: 675 GYDC--RCPHGKNCTGDCIHDGKVKHNGQIWVLENDRCSVCSCQNGFVMCRRMVCD---C 729
Query: 585 AHPLPGTCCPNDCSGCAFGGKEYPSGADFPHPSDP----CRLCRCLSGNVQCLARRCVPL 640
+P C +C + +G + D C+ CRCL G V C C +
Sbjct: 730 ENPTVDLFCCPECDPRLSSQCLHQNGETLYNSGDTWVQNCQQCRCLQGEVDCWPLPCPDV 789
Query: 641 PCPEPVLLPGECCPQCPAAPAPAGCPRPGAAHARHQEY---------FSPPGDPCRRCLC 691
C +L ECCP+C P A R E + G C C C
Sbjct: 790 ECEFSILPENECCPRCVTDPCQADTIRNDITKTCLDEMNVVRFTGSSWIKHGTECTLCQC 849
Query: 692 LDGSVSC 698
+G + C
Sbjct: 850 KNGHICC 856
Score = 104 bits (259), Expect = 4e-22
Identities = 136/553 (24%), Positives = 185/553 (33%), Gaps = 127/553 (22%)
Query: 310 CFLNGREHRSGEPVGSGDPCSHCRCANGSVQCEPLPCPPVPCRHPGK---IPGQCCPVCD 366
C + G +R E G C +C C NG++QCE L CP C + G+CC C
Sbjct: 324 CTMKGTTYREFESWIDG--CKNCTCLNGTIQCETLICPNPDCPLKSALAYVDGKCCKECK 381
Query: 367 G-CEYQGHQY-QSQETFRLQERGLCVRCSCQAGEVSCEEQE-CPVTPCALPAS-----GR 418
C++QG Y + + G+CV C+ + E CP C P S
Sbjct: 382 SICQFQGRTYFEGERNTVYSSSGVCVLYECKDQTMKLVESSGCPALDC--PESHQITLSH 439
Query: 419 QLCPACELDGEEFAEGVQWEPDGRPC------TACVCQDGVPKCGA--VLCPPAP----- 465
C C+ G +F + C C C+DG C
Sbjct: 440 SCCKVCK--GYDFCSERHNCMENSICRNLNDRAVCSCRDGFRALREDNAYCEDIDECAEG 497
Query: 466 ---CQHPTQ---PPGACCPSCD---------SCTYHSQVYANGQNFTDADSPC------H 504
C+ T PG+ C SCT H + N N D ++ C H
Sbjct: 498 RHYCRENTMCVNTPGSFMCICKTGYIRIDDYSCTEHDECITNQHN-CDENALCFNTVGGH 556
Query: 505 ACHCQDGTV----TCSLV---DC-------PPTTCARPQSGPGQCCPRCPDCILEEEVFV 550
C C+ G TC C CA PQ G C D + V
Sbjct: 557 NCVCKPGYTGNGTTCKAFCKDGCRNGGACIAANVCACPQGFTGPSCETDIDECSDGFVQC 616
Query: 551 DGESFSHPRDPCQECRCQEGH----------AHCQP--------RPCPRAPCAHPLPG-- 590
D + C C++G+ C+ C L G
Sbjct: 617 DSRANCINLPGWYHCECRDGYHDNGMFSPSGESCEDIDECGTGRHSCANDTICFNLDGGY 676
Query: 591 TC-CPN--DCSG-CAFGGKEYPSGADFPHPSDPCRLCRCLSGNVQCLARRCVPLPCPEPV 646
C CP+ +C+G C GK +G + +D C +C C +G V C C C P
Sbjct: 677 DCRCPHGKNCTGDCIHDGKVKHNGQIWVLENDRCSVCSCQNGFVMCRRMVC---DCENPT 733
Query: 647 LLPGECCPQCPAAPAPAGCPRPGAAHARHQ--EYFSPPGDP----CRRCLCLDGSVSCQR 700
+ CCP+C PR ++ HQ E GD C++C CL G V C
Sbjct: 734 V-DLFCCPECD--------PRL-SSQCLHQNGETLYNSGDTWVQNCQQCRCLQGEVDCWP 783
Query: 701 LPCPPAPCAHP--RQGPCCPSC---------------DGCLYQGKEFA-SGERFPSPTAA 742
LPCP C + CCP C CL + +G +
Sbjct: 784 LPCPDVECEFSILPENECCPRCVTDPCQADTIRNDITKTCLDEMNVVRFTGSSWIKHGTE 843
Query: 743 CHLCLCWEGSVSC 755
C LC C G + C
Sbjct: 844 CTLCQCKNGHICC 856
Score = 92.4 bits (228), Expect = 1e-18
Identities = 88/321 (27%), Positives = 114/321 (35%), Gaps = 58/321 (18%)
Query: 117 CVCQDGAAHCGPQAHLPHCRGCSQNGQTYGNG-----ETFSPDACTTC--RCLEGTITCN 169
CVC+ G G GC G + F+ +C T C +G + C+
Sbjct: 558 CVCKPGYTGNGTTCKAFCKDGCRNGGACIAANVCACPQGFTGPSCETDIDECSDGFVQCD 617
Query: 170 QKPCPRGPCPE-PGACCPHCKPGCDYEGQLYEEGVTFLSSSNPCLQCT-CLRSRVRCMAL 227
R C PG C+ G Y + F S C C R C
Sbjct: 618 S----RANCINLPGWYHCECRDG-------YHDNGMFSPSGESCEDIDECGTGRHSC--- 663
Query: 228 KCPPSPCPEPVLRPGHCC-----PTCQG-CTEGGSHWEHGQEWTTPGDPCRICRCLEGHI 281
+ C L G+ C C G C G +GQ W D C +C C G +
Sbjct: 664 -ANDTICFN--LDGGYDCRCPHGKNCTGDCIHDGKVKHNGQIWVLENDRCSVCSCQNGFV 720
Query: 282 QCRQRECASLCPYPARPLPGTCCPVCDGCFLNGREHRSGEPV-GSGDP----CSHCRCAN 336
CR+ C C P L CCP CD + H++GE + SGD C CRC
Sbjct: 721 MCRRMVCD--CENPTVDL--FCCPECDPRLSSQCLHQNGETLYNSGDTWVQNCQQCRCLQ 776
Query: 337 GSVQCEPLPCPPVPCRHPGKIPGQCCPVC--DGCEYQGHQYQSQETFRLQERGL------ 388
G V C PLPCP V C +CCP C D C+ + +T L E +
Sbjct: 777 GEVDCWPLPCPDVECEFSILPENECCPRCVTDPCQADTIRNDITKTC-LDEMNVVRFTGS 835
Query: 389 --------CVRCSCQAGEVSC 401
C C C+ G + C
Sbjct: 836 SWIKHGTECTLCQCKNGHICC 856
Score = 83.2 bits (204), Expect = 9e-16
Identities = 117/494 (23%), Positives = 161/494 (32%), Gaps = 152/494 (30%)
Query: 424 CELDGEEFAEGVQWEPDGRPCTACVCQDGVPKCGAVLCPPAPCQHPTQ---PPGACCPSC 480
C + G + E W DG C C C +G +C ++CP C + G CC C
Sbjct: 324 CTMKGTTYREFESWI-DG--CKNCTCLNGTIQCETLICPNPDCPLKSALAYVDGKCCKEC 380
Query: 481 DS-CTYHSQVYANGQNFT--DADSPCHACHCQDGTVT------CSLVDCPPT-------T 524
S C + + Y G+ T + C C+D T+ C +DCP + +
Sbjct: 381 KSICQFQGRTYFEGERNTVYSSSGVCVLYECKDQTMKLVESSGCPALDCPESHQITLSHS 440
Query: 525 CARPQSGPGQCCPR-------------------CPD---CILEEEVFV-DGESFSHPRDP 561
C + G C R C D + E+ + D + + R
Sbjct: 441 CCKVCKGYDFCSERHNCMENSICRNLNDRAVCSCRDGFRALREDNAYCEDIDECAEGRHY 500
Query: 562 CQE------------CRCQEGHAHCQPRPCPR--------------APCAHPLPG----- 590
C+E C C+ G+ C A C + + G
Sbjct: 501 CRENTMCVNTPGSFMCICKTGYIRIDDYSCTEHDECITNQHNCDENALCFNTVGGHNCVC 560
Query: 591 --------TCCPNDCS-GCAFGGK-------EYPSGADFPHPSDPCRLCRCLSGNVQCLA 634
T C C GC GG P G F PS + C G VQC +
Sbjct: 561 KPGYTGNGTTCKAFCKDGCRNGGACIAANVCACPQG--FTGPSCETDIDECSDGFVQCDS 618
Query: 635 R-RCVPLP------CPEP-----VLLP-GECCP--------------------------- 654
R C+ LP C + + P GE C
Sbjct: 619 RANCINLPGWYHCECRDGYHDNGMFSPSGESCEDIDECGTGRHSCANDTICFNLDGGYDC 678
Query: 655 QCPAAPAPAG-CPRPGAAHARHQEYFSPPGDPCRRCLCLDGSVSCQRLPCPPAPCAHPRQ 713
+CP G C G Q + D C C C +G V C+R+ C C +P
Sbjct: 679 RCPHGKNCTGDCIHDGKVKHNGQIWVLE-NDRCSVCSCQNGFVMCRRMVCD---CENPTV 734
Query: 714 GP-CCPSCDG-----CLYQGKE--FASGERFPSPTAACHLCLCWEGSVSCEPKACAPALC 765
CCP CD CL+Q E + SG+ + C C C +G V C P C C
Sbjct: 735 DLFCCPECDPRLSSQCLHQNGETLYNSGDTW---VQNCQQCRCLQGEVDCWPLPCPDVEC 791
Query: 766 PFP--ARGDCCPDC 777
F +CCP C
Sbjct: 792 EFSILPENECCPRC 805
Score = 77.0 bits (188), Expect = 6e-14
Identities = 68/261 (26%), Positives = 97/261 (37%), Gaps = 43/261 (16%)
Query: 119 CQDGAAHCGPQAH---LP---HCR---GCSQNGQTYGNGETFSP-DACTTCR--CLEGTI 166
C DG C +A+ LP HC G NG +GE+ D C T R C TI
Sbjct: 609 CSDGFVQCDSRANCINLPGWYHCECRDGYHDNGMFSPSGESCEDIDECGTGRHSCANDTI 668
Query: 167 TCNQKPCPRGPCPEPGACCPHCKPGCDYEGQLYEEGVTFLSSSNPCLQCTCLRSRVRCMA 226
N CP +C C ++G++ G ++ ++ C C+C V C
Sbjct: 669 CFNLDGGYDCRCPHG----KNCTGDCIHDGKVKHNGQIWVLENDRCSVCSCQNGFVMCRR 724
Query: 227 LKCPPSPCPEPVLRPGHCCPTCQGCTEGGSHWEHGQEWTTPGDP----CRICRCLEGHIQ 282
+ C C P + CCP C ++G+ GD C+ CRCL+G +
Sbjct: 725 MVCD---CENPTVDL-FCCPECDPRLSSQCLHQNGETLYNSGDTWVQNCQQCRCLQGEVD 780
Query: 283 CRQRECASL-CPYPARPLPGTCCPVC--DGCF---------------LNGREHRSGEPVG 324
C C + C + P CCP C D C +N +
Sbjct: 781 CWPLPCPDVECEFSILP-ENECCPRCVTDPCQADTIRNDITKTCLDEMNVVRFTGSSWIK 839
Query: 325 SGDPCSHCRCANGSVQCEPLP 345
G C+ C+C NG + C P
Sbjct: 840 HGTECTLCQCKNGHICCSVDP 860
Score = 63.5 bits (153), Expect = 7e-10
Identities = 48/176 (27%), Positives = 68/176 (38%), Gaps = 39/176 (22%)
Query: 665 CPRPGAAHARHQEYFSPPGDPCRRCLCLDGSVSCQRLPCPPAPCAHPR-----QGPCCPS 719
C G + + + D C+ C CL+G++ C+ L CP C G CC
Sbjct: 324 CTMKGTTYREFESWI----DGCKNCTCLNGTIQCETLICPNPDCPLKSALAYVDGKCCKE 379
Query: 720 CDG-CLYQGKEFASGER--FPSPTAACHLCLCWEGSVSCEPKACAPAL-CP----FPARG 771
C C +QG+ + GER S + C L C + ++ + PAL CP
Sbjct: 380 CKSICQFQGRTYFEGERNTVYSSSGVCVLYECKDQTMKLVESSGCPALDCPESHQITLSH 439
Query: 772 DCCPDCDG-----EGH--------------GIGSCRGGMRETRGLGQNNLYCPRVD 808
CC C G E H + SCR G R R ++N YC +D
Sbjct: 440 SCCKVCKGYDFCSERHNCMENSICRNLNDRAVCSCRDGFRALR---EDNAYCEDID 492
Score = 62.4 bits (150), Expect = 2e-09
Identities = 62/227 (27%), Positives = 80/227 (35%), Gaps = 78/227 (34%)
Query: 87 CECHPASPQCWGL----GRAWPEGARW--EPDACTACVCQDGAAHC--------GPQAHL 132
C C P C G G+ G W E D C+ C CQ+G C P L
Sbjct: 678 CRC-PHGKNCTGDCIHDGKVKHNGQIWVLENDRCSVCSCQNGFVMCRRMVCDCENPTVDL 736
Query: 133 PHCRGCS---------QNGQT-YGNGETFSPDACTTCRCLEGTITCNQKPCPRGPC---- 178
C C QNG+T Y +G+T+ + C CRCL+G + C PCP C
Sbjct: 737 FCCPECDPRLSSQCLHQNGETLYNSGDTWVQN-CQQCRCLQGEVDCWPLPCPDVECEFSI 795
Query: 179 -PEPGACCPHCKPGCDYEGQLYEEGVTFLSSSNPCLQCTCLRSRVRCMALKCPPSPCPEP 237
PE CCP C ++PC Q +R+ +
Sbjct: 796 LPE-NECCPRC-------------------VTDPC-QADTIRNDI--------------- 819
Query: 238 VLRPGHCCPTCQGCTEGGSHW-EHGQEWTTPGDPCRICRCLEGHIQC 283
C GS W +HG E C +C+C GHI C
Sbjct: 820 ---TKTCLDEMNVVRFTGSSWIKHGTE-------CTLCQCKNGHICC 856
>gi|5453766 NEL-like protein 2 isoform b precursor [Homo sapiens]
Length = 816
Score = 127 bits (320), Expect = 3e-29
Identities = 137/561 (24%), Positives = 185/561 (32%), Gaps = 140/561 (24%)
Query: 136 RGCSQNGQTYGNGETFSPDACTTCRCLEGTITCNQKPCPRGPCP-------EPGACCPHC 188
R C+ G TY E++ D C C CL GTI C CP CP G CC C
Sbjct: 272 RTCTMKGTTYREFESWI-DGCKNCTCLNGTIQCETLICPNPDCPLKSALAYVDGKCCKEC 330
Query: 189 KPGCDYEGQLYEEGV--TFLSSSNPCLQCTCLRSRVRCMALK-CPPSPCPEP--VLRPGH 243
K C ++G+ Y EG T SSS C+ C ++ + CP CPE +
Sbjct: 331 KSICQFQGRTYFEGERNTVYSSSGVCVLYECKDQTMKLVESSGCPALDCPESHQITLSHS 390
Query: 244 CCPTCQG---CTEGGSHWEHGQEWTTPGDPCRICR------------------CLEGHIQ 282
CC C+G C+E + E+ CR C EG
Sbjct: 391 CCKVCKGYDFCSERHNCMENSICRNLNDRAVCSCRDGFRALREDNAYCEDIDECAEGRHY 450
Query: 283 CRQRE-CAS-------LCPYPARPLPGTCCPVCDGCFLNGREHRSGEPV----------- 323
CR+ C + +C + C D C N +H E
Sbjct: 451 CRENTMCVNTPGSFMCICKTGYIRIDDYSCTEHDECITN--QHNCDENALCFNTVGGHNC 508
Query: 324 -------GSGDPC-SHCR--CANGS--VQCEPLPCPPVPCRHPGKIPGQCCPVCDGCEYQ 371
G+G C + C+ C NG + CP G C D C
Sbjct: 509 VCKPGYTGNGTTCKAFCKDGCRNGGACIAANVCACPQ------GFTGPSCETDIDEC--- 559
Query: 372 GHQYQSQETFRLQERGLCVR------CSCQAGE----------VSCEE-QECPVT----- 409
S + R C+ C C+ G SCE+ EC
Sbjct: 560 -----SDGFVQCDSRANCINLPGWYHCECRDGYHDNGMFSPSGESCEDIDECGTGRHSCA 614
Query: 410 ------------PCALPASGRQLCPACELDGEEFAEGVQWEPDGRPCTACVCQDGVPKCG 457
C P G+ C DG+ G W + C+ C CQ+G C
Sbjct: 615 NDTICFNLDGGYDCRCP-HGKNCTGDCIHDGKVKHNGQIWVLENDRCSVCSCQNGFVMCR 673
Query: 458 AVLCPPAPCQHPTQPPGACCPSCDSCTYHSQVYANGQNFTDADSP----CHACHCQDGTV 513
++C C++PT CCP CD ++ NG+ ++ C C C G V
Sbjct: 674 RMVCD---CENPTVDL-FCCPECDPRLSSQCLHQNGETLYNSGDTWVQNCQQCRCLQGEV 729
Query: 514 TCSLVDCPPTTCARPQSGPGQCCPRC---------------PDCILEEEVF-VDGESFSH 557
C + CP C +CCPRC C+ E V G S+
Sbjct: 730 DCWPLPCPDVECEFSILPENECCPRCVTDPCQADTIRNDITKTCLDEMNVVRFTGSSWIK 789
Query: 558 PRDPCQECRCQEGHAHCQPRP 578
C C+C+ GH C P
Sbjct: 790 HGTECTLCQCKNGHICCSVDP 810
Score = 115 bits (288), Expect = 2e-25
Identities = 132/547 (24%), Positives = 185/547 (33%), Gaps = 113/547 (20%)
Query: 251 CTEGGSHWEHGQEWTTPGDPCRICRCLEGHIQCRQRECASLCPYPARPLP-------GTC 303
CT G+ + + W D C+ C CL G IQC +CP P PL G C
Sbjct: 274 CTMKGTTYREFESWI---DGCKNCTCLNGTIQCE----TLICPNPDCPLKSALAYVDGKC 326
Query: 304 CPVCDG-CFLNGREHRSGEP---VGSGDPCSHCRCANGSVQC-EPLPCPPVPC--RHPGK 356
C C C GR + GE S C C + +++ E CP + C H
Sbjct: 327 CKECKSICQFQGRTYFEGERNTVYSSSGVCVLYECKDQTMKLVESSGCPALDCPESHQIT 386
Query: 357 IPGQCCPVCDGCEYQGHQYQSQETFRLQERGLCVRCSCQAG-------EVSCEE-QECPV 408
+ CC VC G ++ ++ E + CSC+ G CE+ EC
Sbjct: 387 LSHSCCKVCKGYDFCSERHNCMENSICRNLNDRAVCSCRDGFRALREDNAYCEDIDECAE 446
Query: 409 --------TPCA-LPASGRQLCPA--CELDGEEFAEGVQWEPDGRPCTA----------- 446
T C P S +C +D E + + C
Sbjct: 447 GRHYCRENTMCVNTPGSFMCICKTGYIRIDDYSCTEHDECITNQHNCDENALCFNTVGGH 506
Query: 447 -CVCQDGVPKCGAVLCPPAPCQHPTQPPGAC-------CP---SCDSCTYHSQVYANGQN 495
CVC+ G G A C+ + GAC CP + SC ++G
Sbjct: 507 NCVCKPGYTGNGTTC--KAFCKDGCRNGGACIAANVCACPQGFTGPSCETDIDECSDGFV 564
Query: 496 FTDADSPC------HACHCQDGT----------VTCSLVD--------CPPTTCARPQSG 531
D+ + C + C C+DG +C +D C T G
Sbjct: 565 QCDSRANCINLPGWYHCECRDGYHDNGMFSPSGESCEDIDECGTGRHSCANDTICFNLDG 624
Query: 532 PGQCCPRCP-------DCILEEEVFVDGESFSHPRDPCQECRCQEGHAHCQPRPCPRAPC 584
C RCP DCI + +V +G+ + D C C CQ G C+ C C
Sbjct: 625 GYDC--RCPHGKNCTGDCIHDGKVKHNGQIWVLENDRCSVCSCQNGFVMCRRMVCD---C 679
Query: 585 AHPLPGTCCPNDCSGCAFGGKEYPSGADFPHPSDP----CRLCRCLSGNVQCLARRCVPL 640
+P C +C + +G + D C+ CRCL G V C C +
Sbjct: 680 ENPTVDLFCCPECDPRLSSQCLHQNGETLYNSGDTWVQNCQQCRCLQGEVDCWPLPCPDV 739
Query: 641 PCPEPVLLPGECCPQCPAAPAPAGCPRPGAAHARHQEY---------FSPPGDPCRRCLC 691
C +L ECCP+C P A R E + G C C C
Sbjct: 740 ECEFSILPENECCPRCVTDPCQADTIRNDITKTCLDEMNVVRFTGSSWIKHGTECTLCQC 799
Query: 692 LDGSVSC 698
+G + C
Sbjct: 800 KNGHICC 806
Score = 104 bits (259), Expect = 4e-22
Identities = 136/553 (24%), Positives = 185/553 (33%), Gaps = 127/553 (22%)
Query: 310 CFLNGREHRSGEPVGSGDPCSHCRCANGSVQCEPLPCPPVPCRHPGK---IPGQCCPVCD 366
C + G +R E G C +C C NG++QCE L CP C + G+CC C
Sbjct: 274 CTMKGTTYREFESWIDG--CKNCTCLNGTIQCETLICPNPDCPLKSALAYVDGKCCKECK 331
Query: 367 G-CEYQGHQY-QSQETFRLQERGLCVRCSCQAGEVSCEEQE-CPVTPCALPAS-----GR 418
C++QG Y + + G+CV C+ + E CP C P S
Sbjct: 332 SICQFQGRTYFEGERNTVYSSSGVCVLYECKDQTMKLVESSGCPALDC--PESHQITLSH 389
Query: 419 QLCPACELDGEEFAEGVQWEPDGRPC------TACVCQDGVPKCGA--VLCPPAP----- 465
C C+ G +F + C C C+DG C
Sbjct: 390 SCCKVCK--GYDFCSERHNCMENSICRNLNDRAVCSCRDGFRALREDNAYCEDIDECAEG 447
Query: 466 ---CQHPTQ---PPGACCPSCD---------SCTYHSQVYANGQNFTDADSPC------H 504
C+ T PG+ C SCT H + N N D ++ C H
Sbjct: 448 RHYCRENTMCVNTPGSFMCICKTGYIRIDDYSCTEHDECITNQHN-CDENALCFNTVGGH 506
Query: 505 ACHCQDGTV----TCSLV---DC-------PPTTCARPQSGPGQCCPRCPDCILEEEVFV 550
C C+ G TC C CA PQ G C D + V
Sbjct: 507 NCVCKPGYTGNGTTCKAFCKDGCRNGGACIAANVCACPQGFTGPSCETDIDECSDGFVQC 566
Query: 551 DGESFSHPRDPCQECRCQEGH----------AHCQP--------RPCPRAPCAHPLPG-- 590
D + C C++G+ C+ C L G
Sbjct: 567 DSRANCINLPGWYHCECRDGYHDNGMFSPSGESCEDIDECGTGRHSCANDTICFNLDGGY 626
Query: 591 TC-CPN--DCSG-CAFGGKEYPSGADFPHPSDPCRLCRCLSGNVQCLARRCVPLPCPEPV 646
C CP+ +C+G C GK +G + +D C +C C +G V C C C P
Sbjct: 627 DCRCPHGKNCTGDCIHDGKVKHNGQIWVLENDRCSVCSCQNGFVMCRRMVC---DCENPT 683
Query: 647 LLPGECCPQCPAAPAPAGCPRPGAAHARHQ--EYFSPPGDP----CRRCLCLDGSVSCQR 700
+ CCP+C PR ++ HQ E GD C++C CL G V C
Sbjct: 684 V-DLFCCPECD--------PRL-SSQCLHQNGETLYNSGDTWVQNCQQCRCLQGEVDCWP 733
Query: 701 LPCPPAPCAHP--RQGPCCPSC---------------DGCLYQGKEFA-SGERFPSPTAA 742
LPCP C + CCP C CL + +G +
Sbjct: 734 LPCPDVECEFSILPENECCPRCVTDPCQADTIRNDITKTCLDEMNVVRFTGSSWIKHGTE 793
Query: 743 CHLCLCWEGSVSC 755
C LC C G + C
Sbjct: 794 CTLCQCKNGHICC 806
Score = 92.4 bits (228), Expect = 1e-18
Identities = 88/321 (27%), Positives = 114/321 (35%), Gaps = 58/321 (18%)
Query: 117 CVCQDGAAHCGPQAHLPHCRGCSQNGQTYGNG-----ETFSPDACTTC--RCLEGTITCN 169
CVC+ G G GC G + F+ +C T C +G + C+
Sbjct: 508 CVCKPGYTGNGTTCKAFCKDGCRNGGACIAANVCACPQGFTGPSCETDIDECSDGFVQCD 567
Query: 170 QKPCPRGPCPE-PGACCPHCKPGCDYEGQLYEEGVTFLSSSNPCLQCT-CLRSRVRCMAL 227
R C PG C+ G Y + F S C C R C
Sbjct: 568 S----RANCINLPGWYHCECRDG-------YHDNGMFSPSGESCEDIDECGTGRHSC--- 613
Query: 228 KCPPSPCPEPVLRPGHCC-----PTCQG-CTEGGSHWEHGQEWTTPGDPCRICRCLEGHI 281
+ C L G+ C C G C G +GQ W D C +C C G +
Sbjct: 614 -ANDTICFN--LDGGYDCRCPHGKNCTGDCIHDGKVKHNGQIWVLENDRCSVCSCQNGFV 670
Query: 282 QCRQRECASLCPYPARPLPGTCCPVCDGCFLNGREHRSGEPV-GSGDP----CSHCRCAN 336
CR+ C C P L CCP CD + H++GE + SGD C CRC
Sbjct: 671 MCRRMVCD--CENPTVDL--FCCPECDPRLSSQCLHQNGETLYNSGDTWVQNCQQCRCLQ 726
Query: 337 GSVQCEPLPCPPVPCRHPGKIPGQCCPVC--DGCEYQGHQYQSQETFRLQERGL------ 388
G V C PLPCP V C +CCP C D C+ + +T L E +
Sbjct: 727 GEVDCWPLPCPDVECEFSILPENECCPRCVTDPCQADTIRNDITKTC-LDEMNVVRFTGS 785
Query: 389 --------CVRCSCQAGEVSC 401
C C C+ G + C
Sbjct: 786 SWIKHGTECTLCQCKNGHICC 806
Score = 83.2 bits (204), Expect = 9e-16
Identities = 117/494 (23%), Positives = 161/494 (32%), Gaps = 152/494 (30%)
Query: 424 CELDGEEFAEGVQWEPDGRPCTACVCQDGVPKCGAVLCPPAPCQHPTQ---PPGACCPSC 480
C + G + E W DG C C C +G +C ++CP C + G CC C
Sbjct: 274 CTMKGTTYREFESWI-DG--CKNCTCLNGTIQCETLICPNPDCPLKSALAYVDGKCCKEC 330
Query: 481 DS-CTYHSQVYANGQNFT--DADSPCHACHCQDGTVT------CSLVDCPPT-------T 524
S C + + Y G+ T + C C+D T+ C +DCP + +
Sbjct: 331 KSICQFQGRTYFEGERNTVYSSSGVCVLYECKDQTMKLVESSGCPALDCPESHQITLSHS 390
Query: 525 CARPQSGPGQCCPR-------------------CPD---CILEEEVFV-DGESFSHPRDP 561
C + G C R C D + E+ + D + + R
Sbjct: 391 CCKVCKGYDFCSERHNCMENSICRNLNDRAVCSCRDGFRALREDNAYCEDIDECAEGRHY 450
Query: 562 CQE------------CRCQEGHAHCQPRPCPR--------------APCAHPLPG----- 590
C+E C C+ G+ C A C + + G
Sbjct: 451 CRENTMCVNTPGSFMCICKTGYIRIDDYSCTEHDECITNQHNCDENALCFNTVGGHNCVC 510
Query: 591 --------TCCPNDCS-GCAFGGK-------EYPSGADFPHPSDPCRLCRCLSGNVQCLA 634
T C C GC GG P G F PS + C G VQC +
Sbjct: 511 KPGYTGNGTTCKAFCKDGCRNGGACIAANVCACPQG--FTGPSCETDIDECSDGFVQCDS 568
Query: 635 R-RCVPLP------CPEP-----VLLP-GECCP--------------------------- 654
R C+ LP C + + P GE C
Sbjct: 569 RANCINLPGWYHCECRDGYHDNGMFSPSGESCEDIDECGTGRHSCANDTICFNLDGGYDC 628
Query: 655 QCPAAPAPAG-CPRPGAAHARHQEYFSPPGDPCRRCLCLDGSVSCQRLPCPPAPCAHPRQ 713
+CP G C G Q + D C C C +G V C+R+ C C +P
Sbjct: 629 RCPHGKNCTGDCIHDGKVKHNGQIWVLE-NDRCSVCSCQNGFVMCRRMVCD---CENPTV 684
Query: 714 GP-CCPSCDG-----CLYQGKE--FASGERFPSPTAACHLCLCWEGSVSCEPKACAPALC 765
CCP CD CL+Q E + SG+ + C C C +G V C P C C
Sbjct: 685 DLFCCPECDPRLSSQCLHQNGETLYNSGDTW---VQNCQQCRCLQGEVDCWPLPCPDVEC 741
Query: 766 PFP--ARGDCCPDC 777
F +CCP C
Sbjct: 742 EFSILPENECCPRC 755
Score = 77.0 bits (188), Expect = 6e-14
Identities = 68/261 (26%), Positives = 97/261 (37%), Gaps = 43/261 (16%)
Query: 119 CQDGAAHCGPQAH---LP---HCR---GCSQNGQTYGNGETFSP-DACTTCR--CLEGTI 166
C DG C +A+ LP HC G NG +GE+ D C T R C TI
Sbjct: 559 CSDGFVQCDSRANCINLPGWYHCECRDGYHDNGMFSPSGESCEDIDECGTGRHSCANDTI 618
Query: 167 TCNQKPCPRGPCPEPGACCPHCKPGCDYEGQLYEEGVTFLSSSNPCLQCTCLRSRVRCMA 226
N CP +C C ++G++ G ++ ++ C C+C V C
Sbjct: 619 CFNLDGGYDCRCPHG----KNCTGDCIHDGKVKHNGQIWVLENDRCSVCSCQNGFVMCRR 674
Query: 227 LKCPPSPCPEPVLRPGHCCPTCQGCTEGGSHWEHGQEWTTPGDP----CRICRCLEGHIQ 282
+ C C P + CCP C ++G+ GD C+ CRCL+G +
Sbjct: 675 MVCD---CENPTVDL-FCCPECDPRLSSQCLHQNGETLYNSGDTWVQNCQQCRCLQGEVD 730
Query: 283 CRQRECASL-CPYPARPLPGTCCPVC--DGCF---------------LNGREHRSGEPVG 324
C C + C + P CCP C D C +N +
Sbjct: 731 CWPLPCPDVECEFSILP-ENECCPRCVTDPCQADTIRNDITKTCLDEMNVVRFTGSSWIK 789
Query: 325 SGDPCSHCRCANGSVQCEPLP 345
G C+ C+C NG + C P
Sbjct: 790 HGTECTLCQCKNGHICCSVDP 810
Score = 63.5 bits (153), Expect = 7e-10
Identities = 48/176 (27%), Positives = 68/176 (38%), Gaps = 39/176 (22%)
Query: 665 CPRPGAAHARHQEYFSPPGDPCRRCLCLDGSVSCQRLPCPPAPCAHPR-----QGPCCPS 719
C G + + + D C+ C CL+G++ C+ L CP C G CC
Sbjct: 274 CTMKGTTYREFESWI----DGCKNCTCLNGTIQCETLICPNPDCPLKSALAYVDGKCCKE 329
Query: 720 CDG-CLYQGKEFASGER--FPSPTAACHLCLCWEGSVSCEPKACAPAL-CP----FPARG 771
C C +QG+ + GER S + C L C + ++ + PAL CP
Sbjct: 330 CKSICQFQGRTYFEGERNTVYSSSGVCVLYECKDQTMKLVESSGCPALDCPESHQITLSH 389
Query: 772 DCCPDCDG-----EGH--------------GIGSCRGGMRETRGLGQNNLYCPRVD 808
CC C G E H + SCR G R R ++N YC +D
Sbjct: 390 SCCKVCKGYDFCSERHNCMENSICRNLNDRAVCSCRDGFRALR---EDNAYCEDID 442
Score = 62.4 bits (150), Expect = 2e-09
Identities = 62/227 (27%), Positives = 80/227 (35%), Gaps = 78/227 (34%)
Query: 87 CECHPASPQCWGL----GRAWPEGARW--EPDACTACVCQDGAAHC--------GPQAHL 132
C C P C G G+ G W E D C+ C CQ+G C P L
Sbjct: 628 CRC-PHGKNCTGDCIHDGKVKHNGQIWVLENDRCSVCSCQNGFVMCRRMVCDCENPTVDL 686
Query: 133 PHCRGCS---------QNGQT-YGNGETFSPDACTTCRCLEGTITCNQKPCPRGPC---- 178
C C QNG+T Y +G+T+ + C CRCL+G + C PCP C
Sbjct: 687 FCCPECDPRLSSQCLHQNGETLYNSGDTWVQN-CQQCRCLQGEVDCWPLPCPDVECEFSI 745
Query: 179 -PEPGACCPHCKPGCDYEGQLYEEGVTFLSSSNPCLQCTCLRSRVRCMALKCPPSPCPEP 237
PE CCP C ++PC Q +R+ +
Sbjct: 746 LPE-NECCPRC-------------------VTDPC-QADTIRNDI--------------- 769
Query: 238 VLRPGHCCPTCQGCTEGGSHW-EHGQEWTTPGDPCRICRCLEGHIQC 283
C GS W +HG E C +C+C GHI C
Sbjct: 770 ---TKTCLDEMNVVRFTGSSWIKHGTE-------CTLCQCKNGHICC 806
>gi|40353769 chordin-like 2 [Homo sapiens]
Length = 451
Score = 115 bits (289), Expect = 1e-25
Identities = 89/327 (27%), Positives = 113/327 (34%), Gaps = 68/327 (20%)
Query: 424 CELDGEEFAEGVQWEPDGRP-----CTACVCQDGVP-KCGAVLCPPAPCQHPTQPPGACC 477
C G+ ++ G W P P C C C +G C + CPP C P P CC
Sbjct: 33 CLFHGKRYSPGESWHPYLEPQGLMYCLRCTCSEGAHVSCYRLHCPPVHCPQPVTEPQQCC 92
Query: 478 PSC-------------DSCTYHSQVYANGQNFTDAD-------SPCHACHCQDGTVTCSL 517
P C SC ++ +Y +G+ F+ + + C C C +G + C L
Sbjct: 93 PKCVEPHTPSGLRAPPKSCQHNGTMYQHGEIFSAHELFPSRLPNQCVLCSCTEGQIYCGL 152
Query: 518 VDCPPTTCARPQSGPGQCCPRCPDCILEEEVFVDG----ESFSHPRDPCQECRCQEGHAH 573
CP C P P CC C D E+ D HP+DPC G
Sbjct: 153 TTCPEPGCPAPLPLPDSCCQACKDEASEQSDEEDSVQSLHGVRHPQDPCSS---DAGRKR 209
Query: 574 CQPRPCPR---APCAHPLPGTCCPNDCSG--------------CAFGGKEYPSGADFPHP 616
P P AP + +P P C GGK Y G + HP
Sbjct: 210 GPGTPAPTGLSAPLSF-IPRHFRPKGAGSTTVKIVLKEKHKKACVHGGKTYSHGEVW-HP 267
Query: 617 SD------PCRLCRCLSGNVQCLARRC-VPLPCPEPVLLPGECCPQCPAAPAPAG----- 664
+ PC LC C G C C PC P + G+CC CP A G
Sbjct: 268 AFRAFGPLPCILCTCEDGRQDCQRVTCPTEYPCRHPEKVAGKCCKICPEDKADPGHSEIS 327
Query: 665 ---CPRPGAAHARHQEYFSPPGDPCRR 688
CP+ H SP D RR
Sbjct: 328 STRCPKAPGRVLVHTS-VSPSPDNLRR 353
Score = 96.3 bits (238), Expect = 1e-19
Identities = 79/285 (27%), Positives = 100/285 (35%), Gaps = 58/285 (20%)
Query: 251 CTEGGSHWEHGQEWTTPGDP-----CRICRCLEG-HIQCRQRECASL-CPYPARPLPGTC 303
C G + G+ W +P C C C EG H+ C + C + CP P P C
Sbjct: 33 CLFHGKRYSPGESWHPYLEPQGLMYCLRCTCSEGAHVSCYRLHCPPVHCPQPVTE-PQQC 91
Query: 304 CPVC-------------DGCFLNGREHRSGE--------PVGSGDPCSHCRCANGSVQCE 342
CP C C NG ++ GE P + C C C G + C
Sbjct: 92 CPKCVEPHTPSGLRAPPKSCQHNGTMYQHGEIFSAHELFPSRLPNQCVLCSCTEGQIYCG 151
Query: 343 PLPCPPVPCRHPGKIPGQCCPVC-DGCEYQGHQYQSQETFRLQERGLCVRCSCQAGEVSC 401
CP C P +P CC C D Q + S ++ R CS AG
Sbjct: 152 LTTCPEPGCPAPLPLPDSCCQACKDEASEQSDEEDSVQSLH-GVRHPQDPCSSDAGRKRG 210
Query: 402 EEQECPVTPCALPAS--GRQLCP------------------ACELDGEEFAEGVQWEPDG 441
P T + P S R P AC G+ ++ G W P
Sbjct: 211 PGTPAP-TGLSAPLSFIPRHFRPKGAGSTTVKIVLKEKHKKACVHGGKTYSHGEVWHPAF 269
Query: 442 R-----PCTACVCQDGVPKCGAVLCPPA-PCQHPTQPPGACCPSC 480
R PC C C+DG C V CP PC+HP + G CC C
Sbjct: 270 RAFGPLPCILCTCEDGRQDCQRVTCPTEYPCRHPEKVAGKCCKIC 314
Score = 95.9 bits (237), Expect = 1e-19
Identities = 78/289 (26%), Positives = 109/289 (37%), Gaps = 54/289 (18%)
Query: 192 CDYEGQLYEEGVTFLSSSNP-----CLQCTCLR-SRVRCMALKCPPSPCPEPVLRPGHCC 245
C + G+ Y G ++ P CL+CTC + V C L CPP CP+PV P CC
Sbjct: 33 CLFHGKRYSPGESWHPYLEPQGLMYCLRCTCSEGAHVSCYRLHCPPVHCPQPVTEPQQCC 92
Query: 246 PTC-------------QGCTEGGSHWEHGQEWTTP-------GDPCRICRCLEGHIQCRQ 285
P C + C G+ ++HG+ ++ + C +C C EG I C
Sbjct: 93 PKCVEPHTPSGLRAPPKSCQHNGTMYQHGEIFSAHELFPSRLPNQCVLCSCTEGQIYCGL 152
Query: 286 RECASL-CPYPARPLPGTCCPVC-DGCFLNGREHRSGEPV-GSGDPCSHCRCANGSVQCE 342
C CP P PLP +CC C D E S + + G P C G +
Sbjct: 153 TTCPEPGCPAPL-PLPDSCCQACKDEASEQSDEEDSVQSLHGVRHPQDPCSSDAGRKRGP 211
Query: 343 PLPCPPVPCRHPGKIPGQCCPVCDG---------------CEYQGHQYQSQETFRLQERG 387
P P IP P G C + G Y E + R
Sbjct: 212 GTPAPTGLSAPLSFIPRHFRPKGAGSTTVKIVLKEKHKKACVHGGKTYSHGEVWHPAFRA 271
Query: 388 L----CVRCSCQAGEVSCEEQECPVT-PCALP--ASGR--QLCPACELD 427
C+ C+C+ G C+ CP PC P +G+ ++CP + D
Sbjct: 272 FGPLPCILCTCEDGRQDCQRVTCPTEYPCRHPEKVAGKCCKICPEDKAD 320
Score = 85.1 bits (209), Expect = 2e-16
Identities = 70/284 (24%), Positives = 91/284 (32%), Gaps = 74/284 (26%)
Query: 96 CWGLGRAWPEGARWEPDA-------CTACVCQDGA-----------AHCG-----PQAHL 132
C G+ + G W P C C C +GA HC PQ
Sbjct: 33 CLFHGKRYSPGESWHPYLEPQGLMYCLRCTCSEGAHVSCYRLHCPPVHCPQPVTEPQQCC 92
Query: 133 PHC-------------RGCSQNGQTYGNGETFS---------PDACTTCRCLEGTITCNQ 170
P C + C NG Y +GE FS P+ C C C EG I C
Sbjct: 93 PKCVEPHTPSGLRAPPKSCQHNGTMYQHGEIFSAHELFPSRLPNQCVLCSCTEGQIYCGL 152
Query: 171 KPCPRGPCPE----PGACCPHCKPGCDYEGQLYEEGVTFLSSSNPCLQCTCLRSRVRCMA 226
CP CP P +CC CK + + + +P C+ R R
Sbjct: 153 TTCPEPGCPAPLPLPDSCCQACKDEASEQSDEEDSVQSLHGVRHPQDPCSSDAGRKRGPG 212
Query: 227 LKCPPSPCPEPVLRPGHCCPTCQG---------------CTEGGSHWEHGQEWTTPGD-- 269
P P H P G C GG + HG+ W
Sbjct: 213 TPAPTGLSAPLSFIPRHFRPKGAGSTTVKIVLKEKHKKACVHGGKTYSHGEVWHPAFRAF 272
Query: 270 ---PCRICRCLEGHIQCRQRECASLCPYPAR---PLPGTCCPVC 307
PC +C C +G C++ C + YP R + G CC +C
Sbjct: 273 GPLPCILCTCEDGRQDCQRVTCPT--EYPCRHPEKVAGKCCKIC 314
Score = 80.1 bits (196), Expect = 8e-15
Identities = 72/285 (25%), Positives = 84/285 (29%), Gaps = 109/285 (38%)
Query: 542 CILEEEVFVDGESFSHPRDP-----CQECRCQEG-HAHCQPRPCPRAPCAHPL--PGTCC 593
C+ + + GES+ +P C C C EG H C CP C P+ P CC
Sbjct: 33 CLFHGKRYSPGESWHPYLEPQGLMYCLRCTCSEGAHVSCYRLHCPPVHCPQPVTEPQQCC 92
Query: 594 PNDCS------------GCAFGGKEYPSGADFP----HPS---DPCRLCRCLSGNVQCLA 634
P C G Y G F PS + C LC C G + C
Sbjct: 93 PKCVEPHTPSGLRAPPKSCQHNGTMYQHGEIFSAHELFPSRLPNQCVLCSCTEGQIYCGL 152
Query: 635 RRCVPLPCPEPVLLPGECCPQC------------------------------------PA 658
C CP P+ LP CC C P
Sbjct: 153 TTCPEPGCPAPLPLPDSCCQACKDEASEQSDEEDSVQSLHGVRHPQDPCSSDAGRKRGPG 212
Query: 659 APAPAGCPRPGAAHARHQEYFSPPGD---------------------------------- 684
PAP G P + RH F P G
Sbjct: 213 TPAPTGLSAPLSFIPRH---FRPKGAGSTTVKIVLKEKHKKACVHGGKTYSHGEVWHPAF 269
Query: 685 ------PCRRCLCLDGSVSCQRLPCPPA-PCAHPRQ--GPCCPSC 720
PC C C DG CQR+ CP PC HP + G CC C
Sbjct: 270 RAFGPLPCILCTCEDGRQDCQRVTCPTEYPCRHPEKVAGKCCKIC 314
Score = 70.9 bits (172), Expect = 5e-12
Identities = 47/129 (36%), Positives = 55/129 (42%), Gaps = 26/129 (20%)
Query: 678 YFSPPGDP-CRRCLCLDGS-VSCQRLPCPPAPCAHPRQGP--CCPSC------------- 720
Y P G C RC C +G+ VSC RL CPP C P P CCP C
Sbjct: 49 YLEPQGLMYCLRCTCSEGAHVSCYRLHCPPVHCPQPVTEPQQCCPKCVEPHTPSGLRAPP 108
Query: 721 -----DGCLYQ-GKEFASGERFPSPTA-ACHLCLCWEGSVSCEPKACAPALC--PFPARG 771
+G +YQ G+ F++ E FPS C LC C EG + C C C P P
Sbjct: 109 KSCQHNGTMYQHGEIFSAHELFPSRLPNQCVLCSCTEGQIYCGLTTCPEPGCPAPLPLPD 168
Query: 772 DCCPDCDGE 780
CC C E
Sbjct: 169 SCCQACKDE 177
Score = 43.9 bits (102), Expect = 6e-04
Identities = 24/63 (38%), Positives = 29/63 (46%), Gaps = 8/63 (12%)
Query: 723 CLYQGKEFASGERF-----PSPTAACHLCLCWEGS-VSCEPKACAPALCPFPAR--GDCC 774
CL+ GK ++ GE + P C C C EG+ VSC C P CP P CC
Sbjct: 33 CLFHGKRYSPGESWHPYLEPQGLMYCLRCTCSEGAHVSCYRLHCPPVHCPQPVTEPQQCC 92
Query: 775 PDC 777
P C
Sbjct: 93 PKC 95
>gi|134031945 SCO-spondin [Homo sapiens]
Length = 5147
Score = 114 bits (286), Expect = 3e-25
Identities = 189/778 (24%), Positives = 246/778 (31%), Gaps = 179/778 (23%)
Query: 88 ECHPASPQCWGLGRAWPEGARWEPDACTACVCQDGA----AHCGPQAHLPHCRGCSQNGQ 143
+CH C L G C C G A C P++ P C +GQ
Sbjct: 2897 QCHQEGGPCPRLCLTQGPGIECTGFCAPGCTCPPGLFLHNASCLPRSQCP----CQLHGQ 2952
Query: 144 TYGNGETFSPDACTTCRCLEGTITCNQKPCPRGPCPEPGACCPHCKPGCDYEGQLYEEGV 203
Y +G D+C C C+ G + C + CP P C C+ +
Sbjct: 2953 LYASGAMARLDSCNNCTCVSGKMACTSERCPVACGWSPWTLWSLCSCSCNVGIRRRFRAG 3012
Query: 204 TFLSSSNPCLQCTCLRSRVRCMALKCPPSPCPEPVLRPGHCCPTCQGCTEGGSHWEHG-- 261
T ++ +C +L+ PCP P G P C G + G
Sbjct: 3013 TAPPAAFGGAECQGPTMEAEFCSLR----PCPGPGGEWGPWSPCSVPCGGGYRNRTRGSS 3068
Query: 262 ---QEWTTPG-DPCR-----ICRCLEGHIQCRQ--RECASL---------------CPYP 295
E++T G PC +C + + C Q CA L CP
Sbjct: 3069 RSLMEFSTCGLQPCAGPVPGMCPRDKQWLDCAQGPASCAELSAPRGTNQTCHPGCHCPSG 3128
Query: 296 ARPLPGTCCPVCD-GCFLNGREHRSGEPVGSGDPCSHCRCANGSV-QCEPLPCPP-VPCR 352
L C P D C G + G V PC +C C +G + C PC P
Sbjct: 3129 MLLLNNVCVPTQDCPCAHEGHLYPPGSTVVR--PCENCSCVSGLIANCSSWPCAEGEPTW 3186
Query: 353 HPGKIPGQCCPVCDGCEYQGHQYQSQETFRLQERGLCVRCSCQAGEVSCEEQECPVTPCA 412
P QC C H++ C R S V P
Sbjct: 3187 SPWTPWSQCSASCGPARCHRHRF-------------CAR--------SPSAVPSTVAPLP 3225
Query: 413 LPASGRQLCPA-------CELDGEEFAEGVQWEPDGRPCTAC--VCQDGVPKCGAVLCPP 463
LPA+ LC C L G + A G W P G P + C C G+ P
Sbjct: 3226 LPATPTPLCSGPEAEEEPCLLQGCDRAGG--WGPWG-PWSHCSRSCGGGLRSRTRACDQP 3282
Query: 464 AP------CQHPTQPPGACCPSCDSCTYHSQVYANGQNFTDADSPC-HAC--------HC 508
P C+ P + G C + C + G ++ PC +C C
Sbjct: 3283 PPQGLGDYCEGP-RAQGEVCQAL-PCPVTNCTAIEGAEYSPCGPPCPRSCDDLVHCVWRC 3340
Query: 509 QDGTVTCSLVDCPPTTCARPQSG----PGQCCPRCPDCILEEEVFVDGESFSHPRDPCQE 564
Q G CPP PG C C D +L + G + P D C
Sbjct: 3341 QPGCY------CPPGQVLSSNGAICVQPGHC--SCLD-LLTGQRHHPGARLARP-DGCNH 3390
Query: 565 CRCQEGHAHCQPRPCPRAPCAHPLPGTCCPNDCSGCAFGGKEYPSGADFPHPSDPCRLCR 624
C C EG +C PC P+PG CP +++ S PCR
Sbjct: 3391 CTCLEGRLNCTDLPC-------PVPGGWCP---------------WSEWTMCSQPCR--- 3425
Query: 625 CLSGNVQCLARRCVPLPCPEPVLLPGECC---------PQCPAAPAPAGCPRPGAAHARH 675
G + +R C CP P C Q A P+ A CP GA
Sbjct: 3426 ---GQTRSRSRACA---CPTPQHGGAPCTGEAGEAGAQHQREACPSYATCPVDGA----- 3474
Query: 676 QEYFSP--PGDPCRRCLCLD-GSVSCQRLPCP----PAPCAHPRQGPC---CPSCDGCLY 725
+ P P PC CL S +C R P P P P H + PC C C
Sbjct: 3475 ---WGPWGPWSPCDMCLGQSHRSRACSRPPTPEGGRPCPGNHTQSRPCQENSTQCTDCGG 3531
Query: 726 QGKEFASGERFPSPTAACHL---CLCWEGSVSCEPKACAP-------ALCPFPARGDC 773
G+ P P + L +C GSV C+P P LC PA C
Sbjct: 3532 GQSLHPCGQ--PCPRSCQDLSPGSVCQPGSVGCQPTCGCPLGQLSQDGLCVPPAHCRC 3587
Score = 109 bits (272), Expect = 1e-23
Identities = 205/818 (25%), Positives = 255/818 (31%), Gaps = 197/818 (24%)
Query: 79 TRVRQLESCECHP---ASPQCWGLGRAWPEGARWEPDACTACVCQDGAAHCGPQAHLPHC 135
T VR E+C C A+ W P + W P + C +A CGP H
Sbjct: 3156 TVVRPCENCSCVSGLIANCSSWPCAEGEPTWSPWTP--WSQC-----SASCGPARCHRH- 3207
Query: 136 RGCSQNGQTYGNGETFSPDACTTCRCLEGTITCNQKPCPRGPCPEPGACCP-----HCKP 190
R C+++ + P T G ++PC C G P HC
Sbjct: 3208 RFCARSPSAVPSTVAPLPLPATPTPLCSGP-EAEEEPCLLQGCDRAGGWGPWGPWSHCSR 3266
Query: 191 GCDYEGQLYEEGVTFLSSSNPCLQ---------CTCLRSRVR-CMALKCPPSPCPEPVLR 240
C G S + C Q C R++ C AL CP + C +
Sbjct: 3267 SC---------GGGLRSRTRACDQPPPQGLGDYCEGPRAQGEVCQALPCPVTNCT--AIE 3315
Query: 241 PGHCCPTCQGCTEGGSHWEHGQEWTTPGDPCRICRCLEGHIQCRQRECASLCPYPARPLP 300
P C H PG C C G + ++C P
Sbjct: 3316 GAEYSPCGPPCPRSCDDLVHCVWRCQPG-----CYCPPGQVLSSN---GAICVQPGH--- 3364
Query: 301 GTCCPVCDGCFLNGREHRSGEPVGSGDPCSHCRCANGSVQCEPLPCPPVPCRHPGKIPGQ 360
C D L G+ H G + D C+HC C G + C LPCP +PG
Sbjct: 3365 ---CSCLD--LLTGQRHHPGARLARPDGCNHCTCLEGRLNCTDLPCP---------VPGG 3410
Query: 361 CCPVCDGCEYQGHQYQSQETFRLQERGLCVRCSC------------QAGEVSCEEQECPV 408
CP + + R Q R C+C +AGE + Q
Sbjct: 3411 WCPWSEWT-------MCSQPCRGQTRSRSRACACPTPQHGGAPCTGEAGEAGAQHQ---- 3459
Query: 409 TPCALPASGRQLCPA---CELDGEEFAEGVQWEPDG--RPCTACVCQDGVPK-CGAVLCP 462
R+ CP+ C +DG W P G PC C+ Q + C P
Sbjct: 3460 ---------REACPSYATCPVDG-------AWGPWGPWSPCDMCLGQSHRSRACSRPPTP 3503
Query: 463 ----PAPCQHPTQPPGACCPSCDSCTYHSQVYANGQNFTDADSPC-HACH-------CQD 510
P P H P C + CT GQ+ PC +C CQ
Sbjct: 3504 EGGRPCPGNHTQSRP--CQENSTQCT----DCGGGQSLHPCGQPCPRSCQDLSPGSVCQP 3557
Query: 511 GTVTCSLVDCPPTTCARPQ-SGPGQCCP----RC---PDC--ILEEEVFVDGESFS---- 556
G+V C P C Q S G C P RC P I E + G FS
Sbjct: 3558 GSVGCQ----PTCGCPLGQLSQDGLCVPPAHCRCQYQPGAMGIPENQSRSAGSRFSSWES 3613
Query: 557 -HPRD----PCQECRCQEGHAHCQPRP-CPRAPCAHPLPGTCCP----NDCSGCAFGGKE 606
P + PC C C G CQ P CP PG DCS GG++
Sbjct: 3614 LEPGEVVTGPCDNCTCVAGILQCQEVPDCPD-------PGVWSSWGPWEDCSVSCGGGEQ 3666
Query: 607 YPSG--ADFPHPSDPCRLCRCLSGNVQCLARRCVPLPCPEPVLL----PGECCP-QCPAA 659
S A P P P R R C + C CP L PGE CP C
Sbjct: 3667 LRSRRCARPPCPG-PARQSR------TCSTQVCREAGCPAGRLYRECQPGEGCPFSCAHV 3719
Query: 660 PAPAGCPRPGAAHARHQEYFSPPGDPCRRCLCLDGSVSCQRLPCPPAPCAHPRQGPCCPS 719
GC G H P G R C+ Q PC G
Sbjct: 3720 TQQVGCFSEGCEEGCH----CPEGTFQHRLACV------QECPCVLTAWLLQELGATIGD 3769
Query: 720 CDGCLYQGKEFASGERFPSPTAACHLCLCWEGSVSCEPKACAPA---LCPFPARGDCCPD 776
L G E SG+ +C C C G +SC C A P+ G C
Sbjct: 3770 PGQPLGPGDELDSGQTL---RTSCGNCSCAHGKLSCSLDDCFEADGGFGPWSPWGPCSRS 3826
Query: 777 CDGEGHGIGS--CRGGMRETRGLG----QNNLYCPRVD 808
C G G S C M G G + +L CP D
Sbjct: 3827 CGGLGTRTRSRQCVLTMPTLSGQGCRGPRQDLECPSPD 3864
Score = 99.4 bits (246), Expect = 1e-20
Identities = 201/820 (24%), Positives = 246/820 (30%), Gaps = 204/820 (24%)
Query: 117 CVCQDGA----AHCGPQAHLPHCRGCSQNGQTYGNGETFSPDACTTCRCLEGTITCNQKP 172
C C G C P + P C + G +F C+ C C +G + C
Sbjct: 2656 CRCPPGLLLHDTRCLPLSECP----CLVGEELKWPGVSFLLGNCSQCVCEKGELLCQPGG 2711
Query: 173 CP--------------------------RGPCPEP----GACC-------PHCKPGCDYE 195
CP R P P GA C C C E
Sbjct: 2712 CPLPCGWSAWSSWAPCDRSCGSGVRARFRSPSNPPAAWGGAPCEGDRQELQGCHTVCGTE 2771
Query: 196 GQLYEEGVTFLSSSNPCLQ---CTCLRSRVRCMALKCP---PSPCPEPVLRPGHCCPTCQ 249
+ ++ S S CL RSR R CP S CP + C P
Sbjct: 2772 VFGWTPWTSWSSCSQSCLAPGGGPGWRSRSRL----CPSPGDSSCPGDATQEEPCSPP-- 2825
Query: 250 GCTEGGSHWEHGQEWTTPGDPCRICRCLEGHIQCRQRECASL------CPYPARPLPGTC 303
S W W+T PC +G IQ R R C+SL CP P
Sbjct: 2826 -VCPVPSIWGLWAPWSTCSAPC------DGGIQTRGRSCSSLAPGDTTCPGPHSQTRDCN 2878
Query: 304 CPVCDGCFLNGREHRSGEPV-GSGDPCSH-CRCANGSVQCEPL-----PCPPVPCRHPGK 356
C RS E G PC C ++C CPP H
Sbjct: 2879 TQPCTAQCPENMLFRSAEQCHQEGGPCPRLCLTQGPGIECTGFCAPGCTCPPGLFLHNAS 2938
Query: 357 -IPGQCCPVCDGCEYQGHQYQSQETFRLQERGLCVRCSCQAGEVSCEEQECPVTPCALPA 415
+P CP C+ G Y S RL C C+C +G+++C + CPV P
Sbjct: 2939 CLPRSQCP----CQLHGQLYASGAMARLDS---CNNCTCVSGKMACTSERCPVACGWSPW 2991
Query: 416 SGRQLC-----------------PACELDGEEFAEGVQWEPDG---RPCTACVCQDG--- 452
+ LC P G E +G E + RPC + G
Sbjct: 2992 TLWSLCSCSCNVGIRRRFRAGTAPPAAFGGAE-CQGPTMEAEFCSLRPCPGPGGEWGPWS 3050
Query: 453 ---VPKCGA----------------VLCPPAPCQHPTQPPGACCPSCD--SCTYHSQVYA 491
VP CG C PC P PG C C A
Sbjct: 3051 PCSVP-CGGGYRNRTRGSSRSLMEFSTCGLQPCAGPV--PGMCPRDKQWLDCAQGPASCA 3107
Query: 492 NGQNFTDADSPCH-ACHCQDGTVTCSLVDCPPTTCARPQSG----PGQCCPR-CPDCILE 545
+ CH CHC G + + V P C G PG R C +C
Sbjct: 3108 ELSAPRGTNQTCHPGCHCPSGMLLLNNVCVPTQDCPCAHEGHLYPPGSTVVRPCENCSCV 3167
Query: 546 EEVF--------VDGESFSHPRDPCQECRCQEGHAHC-QPRPCPRAPCA-------HPLP 589
+ +GE P P +C G A C + R C R+P A PLP
Sbjct: 3168 SGLIANCSSWPCAEGEPTWSPWTPWSQCSASCGPARCHRHRFCARSPSAVPSTVAPLPLP 3227
Query: 590 GTCCPNDCSG-------CAFGGKEYPSGADFPHPSDPCRLCRCLSGNVQCLARRCVPLP- 641
T P CSG C G + G P C R G ++ R C P
Sbjct: 3228 ATPTPL-CSGPEAEEEPCLLQGCDRAGGWGPWGPWSHC--SRSCGGGLRSRTRACDQPPP 3284
Query: 642 ------CPEPVLLPGECCPQCPAAPAPAGCPRPGAAHARHQEYFSPPGDPCRRCLCLDGS 695
C P GE C P CP EY SP G PC R D
Sbjct: 3285 QGLGDYCEGP-RAQGEVCQALP-------CPVTNCTAIEGAEY-SPCGPPCPR--SCDDL 3333
Query: 696 VSC-----QRLPCPP--------APCAHPRQGPCCPSCDGCLYQGKEFASGERFPSPTAA 742
V C CPP A C P C L G+ G R P
Sbjct: 3334 VHCVWRCQPGCYCPPGQVLSSNGAICVQPGHCSCLD-----LLTGQRHHPGARLARPD-G 3387
Query: 743 CHLCLCWEGSVSCEPKAC--APALCPFPARGDCCPDCDGE 780
C+ C C EG ++C C CP+ C C G+
Sbjct: 3388 CNHCTCLEGRLNCTDLPCPVPGGWCPWSEWTMCSQPCRGQ 3427
Score = 98.6 bits (244), Expect = 2e-20
Identities = 203/818 (24%), Positives = 260/818 (31%), Gaps = 236/818 (28%)
Query: 91 PASPQC-WGLGRAWPEGARWEPDACTACVCQDGAAHCGP-----QAHLPHCRG----CSQ 140
PAS C WG ++P G+ + D C C CQ+G HCG + +P C C +
Sbjct: 1328 PASCPCEWGRN-SFPPGSVLQKD-CGNCTCQEGQWHCGGDGGHCEELVPACAEGEALCQE 1385
Query: 141 NGQTYGN----------GETFSPDACTTCRCLEGTITCNQKPC----------------- 173
NG + G+ + C C EG +TC+ C
Sbjct: 1386 NGHCVPHGWLCDNQDDCGDGSDEEGCAAPGCGEGQMTCSSGHCLPLALLCDRQDDCGDGT 1445
Query: 174 --PRGPCPE------------PGACC---PHCKPGCDYEGQLYEEGVTFLSSSNPCLQCT 216
P PCP+ P C P C D E L + VT + C+ T
Sbjct: 1446 DEPSYPCPQGLLACADGRCLPPALLCDGHPDCLDAADEESCLGQ--VTCVPGEVSCVDGT 1503
Query: 217 CLRSRVRCMAL-KCP------PSPCPEPVLRPGHCCPTCQGCTEGGSHWEHGQ-EWTTPG 268
CL + C + CP P CP P L P T G + G +P
Sbjct: 1504 CLGAIQLCDGVWDCPDGADEGPGHCPLPSL-PTPPASTLPGPSPGSLDTASSPLASASPA 1562
Query: 269 DPCR--ICRCLEGHI-----QCRQRE-CAS-----LCPYPARPLPGTCC---------PV 306
PC RC G +C Q E CA C P P C +
Sbjct: 1563 PPCGPFEFRCGSGECTPRGWRCDQEEDCADGSDERGCGGPCAPHHAPCARGPHCVSPEQL 1622
Query: 307 CDG---CFLNGREHRS--------GEPVGSGDPCSHCRCANGSVQCEPLPCPPVP-CRHP 354
CDG C E G P +G PC C NG+ L C P C P
Sbjct: 1623 CDGVRQCPDGSDEGPDACGGLPALGGPNRTGLPCPEYTCPNGTCIGFQLVCDGQPDCGRP 1682
Query: 355 GKIPGQCCPVCDGCEYQGHQY---QSQETFRLQERGLCVRCSCQAGEVSCEEQECPVTPC 411
G++ P GC G T +G RCS V Q CP
Sbjct: 1683 GQVGPS--PEEQGCGAWGPWSPWGPCSRTCGPWGQGRSRRCSPLGLLVL---QNCPG--- 1734
Query: 412 ALPASGRQLC--PACELDGEEFAEGVQWEPDGRPCTACVC--------QDGVPKCGAV-- 459
P Q C AC +DG E++ W PC + Q+G C A+
Sbjct: 1735 --PEHQSQACFTAACPVDG-EWSTWSPWSVCSEPCRGTMTRQRQCHSPQNGGRTCAALPG 1791
Query: 460 ---------LCPPAPCQHPT-------QPPGACCPSCDSCTYHSQVYANGQNFTDADSPC 503
CP C + T QP C +CD +GQ D PC
Sbjct: 1792 GLHSTRQTKPCPQDGCPNATCSGELMFQPCAPCPLTCDD--------ISGQVTCPPDWPC 1843
Query: 504 HA--CHCQDGTVTCSLVDCPPTTCARPQSGPGQCCPRCPDCILEEEVFVDGESFSHPRDP 561
+ C C +G V S C P+ +CP C+++ + G+ +
Sbjct: 1844 GSPGCWCPEGQVLGS-----EGWCVWPR--------QCP-CLVDGARYWPGQRI---KAD 1886
Query: 562 CQECRCQEGH----------------------AHC-----------------QPRPCPRA 582
CQ C CQ+G A C PRP R
Sbjct: 1887 CQLCICQDGRPRRCRLNPDCAVDCGWSSWSPWAKCLGPCGSQSIQWSFRSSNNPRPSGRG 1946
Query: 583 -PC--AHPLPGTCCPNDCSGCAFGGKEYPSGADFPHPSDPCRLCRCLSGNVQCLARRCVP 639
C H C C GC G+ + G + PCR+C+CL + C
Sbjct: 1947 RQCRGIHRKARRCQTEPCEGCEHQGQVHRVGERW--HGGPCRVCQCLHNLTAHCSPYCPL 2004
Query: 640 LPCPEPVLL---PGECCPQCP-----------AAPAPAGCPRPGAAHARHQEYFSPPGDP 685
CP+ +L GE C C A PA A P P P GDP
Sbjct: 2005 GSCPQGWVLVEGTGESCCHCALPGENQTVQPMATPAAAPAPSPQIRFPLATYILPPSGDP 2064
Query: 686 CRRCLCLDG------SVSCQRL--PCPPAPCAHPRQGP 715
C L L G S Q+L P A P QGP
Sbjct: 2065 CYSPLGLAGLAEGSLHASSQQLEHPTQAALLGAPTQGP 2102
Score = 95.1 bits (235), Expect = 2e-19
Identities = 139/562 (24%), Positives = 188/562 (33%), Gaps = 156/562 (27%)
Query: 170 QKPCPRGPCPEPGACCPHCKPGCDYEGQLYEEGVTFLSSSNPCLQ-CTCLRSRVRCMALK 228
Q+ C GPCPE A ++ V L +N C C L RV+C+
Sbjct: 4656 QESCNGGPCPECEA----------------QDTVFTLDCANQCPHSCADLWDRVQCLQGP 4699
Query: 229 CPPS-PCPE-PVLRPGHCCP--TCQ-GCTEGGSHWEHGQEWTTPGDPCRICRCLEGHIQC 283
C P CP +++ G C P +C+ G + WE D C+ C C+ + C
Sbjct: 4700 CRPGCRCPPGQLVQDGRCVPISSCRCGLPSANASWELAPAQAVQLD-CQNCTCVNESLVC 4758
Query: 284 RQRECASLCPYPARPLPGTCCPVCDGCFLNGREHRSGEPVGSGDPCSHCRCANGSVQCEP 343
+EC L P+ A +C C G + HR+ E PC + +C
Sbjct: 4759 PHQECPVLGPWSAW---SSCSAPCGGGTME--RHRTCEGGPGVAPCQ-AQDTEQRQECNL 4812
Query: 344 LPCPPVP---------------CRH--PGKI-------PGQCCP--------VC---DGC 368
PCP P C H PG I PG CP C C
Sbjct: 4813 QPCPECPPGQVLSACATSCPCLCWHLQPGAICVQEPCQPGCGCPGGQLLHNGTCVPPTAC 4872
Query: 369 EYQGHQYQSQETFRLQERGL-----------CVRCSCQAGEVSCEEQECPVTPCALPASG 417
H T L+E+ C RC C G SC +C V P +
Sbjct: 4873 PCTQHSLPWGLTLTLEEQAQELPPGTVLTRNCTRCVCHGGAFSCSLVDCQVPP---GETW 4929
Query: 418 RQLCPA----CELDGEEF-AEGVQWEPDGRPCTACVCQDGVPKCGAVLCPPAPCQHPTQP 472
+Q+ P CE E A Q + CVCQ G H
Sbjct: 4930 QQVAPGELGLCEQTCLEMNATKTQSNCSSARASGCVCQPG---------------HFRSQ 4974
Query: 473 PGACCPS--CDSCTYHSQVYANGQNFTDADSPCHACHCQDGTVTCSLVDCPPTTCARPQS 530
G C P C+ C + + + G + +A C +C C G C+ C P TCA+ +
Sbjct: 4975 AGPCVPEDHCE-CWHLGRPHLPGSEWQEA---CESCLCLSGRPVCT-QHCSPLTCAQGEE 5029
Query: 531 ---GPGQCCPRC---------PDCILEEEV--FVDGESFSHPRDPCQECRCQEGHAHCQP 576
PG CCP C P C L E+ F G + D + C G+
Sbjct: 5030 MVLEPGSCCPSCRREAPEEQSPSCQLLTELRNFTKGTCY---LDQVEVSYC-SGYCPSST 5085
Query: 577 RPCPRAPCAHPLPGTCCPNDCSGCAFGGKEYPSGADFPHPSDPCRL--CRCLSGNVQCLA 634
P P + C C++ P P R+ RCL G+
Sbjct: 5086 HVMPEEPYLQ--------SQCDCCSYR----------LDPESPVRILNLRCLGGHT---- 5123
Query: 635 RRCVPLPCPEPVLLPGECCPQC 656
EPV+LP QC
Sbjct: 5124 ---------EPVVLPVIHSCQC 5136
Score = 90.1 bits (222), Expect = 7e-18
Identities = 209/925 (22%), Positives = 266/925 (28%), Gaps = 246/925 (26%)
Query: 83 QLESCECHPASPQCWGLGRAWPEGARWEPDACTACVCQDGAAHC-GPQAHLPHC----RG 137
Q + C P C R+ G W C C C C + +P
Sbjct: 4202 QSQPCPQPSCPPLCLQGTRSRTLGDSWLQGECQRCSCTPEGVICEDTECAVPEAWTLWSS 4261
Query: 138 CSQNGQTYGNGETFSPDACTTCR-------CLEGTITCNQKPCPR-------GPCPEPGA 183
S + G G AC CL Q+PCP GP G
Sbjct: 4262 WSDCPVSCGGGNQVRTRACRAAAPHHRSPPCLGPDTQTRQQPCPGLLEACSWGPW---GP 4318
Query: 184 CCPHCKPGCDYEGQLYEEGVTFLSSSNPCLQC----TCLRSRVRCMALKCPPSPCPEPVL 239
C C PG + S S PCL TC + + C PCPE +
Sbjct: 4319 CSRSCGPG-----------LASRSGSCPCLMAKADPTCNSTFLHLDTQGCYSGPCPEECV 4367
Query: 240 RPGHCCPTCQGCT----EGGSHWEHGQEWTTPGDPCRICRCLEGHIQ------CRQRECA 289
T C + H G PC L+GH + C + C
Sbjct: 4368 WSSWSSWTRCSCRVLVQQRYRHQGPASRGARAGAPCTR---LDGHFRPCLISNCSEDSCT 4424
Query: 290 SLCPYPARPLPGTCCPVCDGCFLNGREHRSGEPVGSGDPCSH-CRCANGSVQCEPLPCPP 348
P+ C +C H S + PC C C G ++ PP
Sbjct: 4425 P--PFEFHACGSPCAGLC-------ATHLSHQLCQDLPPCQPGCYCPKGLLEQAGGCIPP 4475
Query: 349 VPCRHPGKIPGQCCPVCDGCEYQGHQYQSQETFRLQERGLCVRCSCQAGEVSCEEQEC-- 406
C C G RLQ C C C+ GE+ C Q C
Sbjct: 4476 EECN------------CWHTSAAGAGMTLAPGDRLQLG--CKECECRRGELHCTSQGCQG 4521
Query: 407 -----------PVTPCALPASGRQLCPACELDGEE--FAEGVQWEPDGRPCTAC------ 447
P PC P++ L PA EE + P P A
Sbjct: 4522 LLPLSEWSEWSPCGPCLPPSA---LAPASRTALEEHWLRDPTGLSPTLAPLLASEQHRHR 4578
Query: 448 VCQD---GVPKCGAV-LCP-PAPCQHPTQPPGACCPSCDSCTYHS----QVYANGQ---N 495
+C D G P GA LC P Q PGAC SC + QV +G
Sbjct: 4579 LCLDPATGRPWTGAPHLCTAPLSQQRLCPDPGACPDSCQWSLWGPWSPCQVPCSGGFRLR 4638
Query: 496 FTDADS------------------PCHACHCQDGTVTCSLVDCPPTTCA----RPQSGPG 533
+ +A++ PC C QD T + P +CA R Q G
Sbjct: 4639 WREAEALCGGGCREPWAQESCNGGPCPECEAQDTVFTLDCANQCPHSCADLWDRVQCLQG 4698
Query: 534 QCCP--RCPDCILEEE----------VFVDGESFSHPRDP-------CQECRCQEGHAHC 574
C P RCP L ++ + + S P CQ C C C
Sbjct: 4699 PCRPGCRCPPGQLVQDGRCVPISSCRCGLPSANASWELAPAQAVQLDCQNCTCVNESLVC 4758
Query: 575 QPRPCPR-------APCAHPLPGTCCPNDCSGCAFGGKEYPSGADFPHPSDPCRLCRCLS 627
+ CP + C+ P G + C G P A C L C
Sbjct: 4759 PHQECPVLGPWSAWSSCSAPCGGGTMERHRT-CEGGPGVAPCQAQDTEQRQECNLQPCPE 4817
Query: 628 GNV-QCLARRCVPLPCPEPVLLPGECCPQCPAAPAPAGCPRPGAAH-------------- 672
Q L+ PC L PG C Q P P GCP H
Sbjct: 4818 CPPGQVLSACATSCPCLCWHLQPGAICVQEPCQPG-CGCPGGQLLHNGTCVPPTACPCTQ 4876
Query: 673 ----------ARHQEYFSPPGDP----CRRCLCLDGSVSCQRLPCPPAP----------- 707
Q PPG C RC+C G+ SC + C P
Sbjct: 4877 HSLPWGLTLTLEEQAQELPPGTVLTRNCTRCVCHGGAFSCSLVDCQVPPGETWQQVAPGE 4936
Query: 708 -------------------CAHPR--------------QGPCCPS--CDGCLYQGKEFAS 732
C+ R GPC P C+ C + G+
Sbjct: 4937 LGLCEQTCLEMNATKTQSNCSSARASGCVCQPGHFRSQAGPCVPEDHCE-CWHLGRPHLP 4995
Query: 733 GERFPSPTAACHLCLCWEG----SVSCEPKACAPALCPFPARGDCCPDCDGEG--HGIGS 786
G + AC CLC G + C P CA G CCP C E S
Sbjct: 4996 GSEWQE---ACESCLCLSGRPVCTQHCSPLTCAQGEEMVLEPGSCCPSCRREAPEEQSPS 5052
Query: 787 CRGGMRETRGLGQNNLYCPRVDLKY 811
C+ + E R + Y +V++ Y
Sbjct: 5053 CQ-LLTELRNFTKGTCYLDQVEVSY 5076
Score = 77.8 bits (190), Expect = 4e-14
Identities = 113/478 (23%), Positives = 149/478 (31%), Gaps = 110/478 (23%)
Query: 156 CTTCRCLEGTITCNQKPCP-RGPCPEPGACCPHCKPGCDYEGQLYEEGVTFLSSSNPCLQ 214
C C C+ ++ C + CP GP +C C G + E G PC Q
Sbjct: 4746 CQNCTCVNESLVCPHQECPVLGPWSAWSSCSAPCGGGTMERHRTCEGG----PGVAPC-Q 4800
Query: 215 CTCLRSRVRCMALKCPPSPCPEPVLRPGHCCPTCQGCTEGGSHWEHGQEWTTPGDPCRIC 274
R C CP P PG C C
Sbjct: 4801 AQDTEQRQECNLQPCPECP-------PGQVLSAC----------------------ATSC 4831
Query: 275 RCLEGHIQ----CRQRECASLCPYPARPL-------PGTCCPVCD-----GCFLNGREHR 318
CL H+Q C Q C C P L P T CP G L E
Sbjct: 4832 PCLCWHLQPGAICVQEPCQPGCGCPGGQLLHNGTCVPPTACPCTQHSLPWGLTLTLEEQA 4891
Query: 319 SGEPVGS--GDPCSHCRCANGSVQCEPLPCPPVPCRHPGKIPGQCCPVCDG-CEYQGHQY 375
P G+ C+ C C G+ C + C VP PG+ Q P G CE +
Sbjct: 4892 QELPPGTVLTRNCTRCVCHGGAFSCSLVDC-QVP---PGETWQQVAPGELGLCEQTCLEM 4947
Query: 376 QSQETFRLQERGLCVRCSCQAGEVSCEEQEC-PVTPCALPASGRQLCPACELDGEEFAEG 434
+ +T C CQ G + C P C GR P G
Sbjct: 4948 NATKTQSNCSSARASGCVCQPGHFRSQAGPCVPEDHCECWHLGRPHLP-----------G 4996
Query: 435 VQWEPDGRPCTACVCQDGVPKCGAVLCPPAPC---QHPTQPPGACCPSC-----DSCTYH 486
+W+ C +C+C G P C C P C + PG+CCPSC + +
Sbjct: 4997 SEWQ---EACESCLCLSGRPVC-TQHCSPLTCAQGEEMVLEPGSCCPSCRREAPEEQSPS 5052
Query: 487 SQVYANGQNFTDADSPCHACHCQDGTVTCSLVDCPPTTCARPQSGPGQCCPRCPDCILEE 546
Q+ +NFT C+ V+ CP +T P+ Q +C C
Sbjct: 5053 CQLLTELRNFTKG-----TCYLDQVEVSYCSGYCPSSTHVMPEEPYLQ--SQCDCCSYRL 5105
Query: 547 EVFVDGESFSHPRDPCQ--ECRCQEGHAHCQPRPCPRAPCAHPLPGTCCPNDCSGCAF 602
+ P P + RC GH P P+ +C + C G F
Sbjct: 5106 D----------PESPVRILNLRCLGGHTE---------PVVLPVIHSCQCSSCQGGDF 5144
Score = 77.0 bits (188), Expect = 6e-14
Identities = 187/797 (23%), Positives = 240/797 (30%), Gaps = 206/797 (25%)
Query: 77 LQTRVRQLESCECHPA--SPQCWGLGRAWPEGARWEPDACTACVCQDGAAHCGPQAHLPH 134
LQ R L SC P P C +W A WEP + + V Q +A+ P
Sbjct: 3921 LQERPCNLPSCTELPVCPGPGCGAGNCSWTSWAPWEPCSRSCGVGQQRRL----RAYRPP 3976
Query: 135 CRGCSQNGQTYGNGETFSPDACTTCRCLEGTITCNQKPCPRGPCPEPGACC-----PHCK 189
G G + P+ T + ++ C CP PG C
Sbjct: 3977 -----------GPGGHWCPNILTAYQ--------ERRFCNLRACPVPGGWSRWSPWSWCD 4017
Query: 190 PGCDYEGQLYEEGVTFLSSSNPCLQCTCLRSRVRCMALKCPPSPCPEPVLRPGHCCPTCQ 249
C L + S N C R + R C P PC CP
Sbjct: 4018 RSCGGGQSLRSRSCSSPPSKNGGAPCAGERHQARL----CNPMPCEAG-------CPA-- 4064
Query: 250 GCTEGGSHWEHGQEWTTPGDPC-RICRCLEGHIQCR-----QRECASLCPYPARPLPGTC 303
G E T + C R C L+ I C+ Q+ C CP + G C
Sbjct: 4065 -----------GMEVVTCANRCPRRCSDLQEGIVCQDDQVCQKGCR--CPKGSLEQDGGC 4111
Query: 304 CPV--CDGCFLNGREHRSGEPVGSGDPCSHCRCANGSVQCEPLPCPP------------V 349
P+ CD G G D C++C C G + C PCPP
Sbjct: 4112 VPIGHCDCTDAQGHSWAPGSQ--HQDACNNCSCQAGQLSCTAQPCPPPTHCAWSHWSAWS 4169
Query: 350 PCRHPGKIPGQ------------------------------CCPVCDGCEYQGHQYQSQE 379
PC H GQ C P+C QG + ++
Sbjct: 4170 PCSHSCGPRGQQSRFRSSTSGSWAPECREEQSQSQPCPQPSCPPLC----LQGTRSRTLG 4225
Query: 380 TFRLQERGLCVRCSCQAGEVSCEEQECPVTPCALPASGRQLCPACELDGEEFAEGVQWEP 439
LQ G C RCSC V CE+ EC V S CP G +
Sbjct: 4226 DSWLQ--GECQRCSCTPEGVICEDTECAVPEAWTLWSSWSDCPVSCGGGNQVRT------ 4277
Query: 440 DGRPCTACVCQDGVPKCGAVLCPPA-----PCQHPTQ-----PPGACCPSCDSCTYHSQV 489
R C A P C L P PC + P G C SC S+
Sbjct: 4278 --RACRAAAPHHRSPPC---LGPDTQTRQQPCPGLLEACSWGPWGPCSRSCGP-GLASRS 4331
Query: 490 YANGQNFTDADSPCHACHCQDGTVTCSLVDCPPTTCARPQSGPGQCCPRCPDCILEEEVF 549
+ AD C++ T C CP S +C R +L ++ +
Sbjct: 4332 GSCPCLMAKADPTCNSTFLHLDTQGCYSGPCPEECVWSSWSSWTRCSCR----VLVQQRY 4387
Query: 550 VDGESFSHPRDPCQECRCQEGHAH-CQPRPCPRAPCAHPLPGTCCPNDCSGCAFGGKEYP 608
S C +GH C C C P C + C+G +
Sbjct: 4388 RHQGPASRGARAGAPCTRLDGHFRPCLISNCSEDSCTPPFEFHACGSPCAGLCATHLSHQ 4447
Query: 609 SGADFPHPSDPCRL-CRCLSGNVQCLARRCVPLPCPEPVLLPGECCPQCPAAPAPAGCPR 667
D P PC+ C C G ++ A C+P P EC C
Sbjct: 4448 LCQDLP----PCQPGCYCPKGLLE-QAGGCIP---------PEEC-----------NCWH 4482
Query: 668 PGAAHARHQEYFSPPGD----PCRRCLCLDGSVSCQRLPCPP----------APCAHPRQ 713
AA A PGD C+ C C G + C C +PC
Sbjct: 4483 TSAAGA---GMTLAPGDRLQLGCKECECRRGELHCTSQGCQGLLPLSEWSEWSPC----- 4534
Query: 714 GPCCPSCDGCLYQGKEFASGERF------PSPTAACHLC-------LCWEGSVSCEPKAC 760
GPC P L A E + SPT A L LC + + P
Sbjct: 4535 GPCLP--PSALAPASRTALEEHWLRDPTGLSPTLAPLLASEQHRHRLCLDPATG-RPWTG 4591
Query: 761 APALCPFP-ARGDCCPD 776
AP LC P ++ CPD
Sbjct: 4592 APHLCTAPLSQQRLCPD 4608
Score = 71.6 bits (174), Expect = 3e-12
Identities = 175/748 (23%), Positives = 219/748 (29%), Gaps = 179/748 (23%)
Query: 108 RWEPDACTACVCQDGAAH--CGPQAHLPHCRGCSQNGQTYGNGETFSPDACTTCRCLEGT 165
RW + C+ G + CGP P C Q+ + + C C+EG
Sbjct: 1264 RWRSQELCSLQCEGGQVYEACGPTCP-PTCH--EQHPEPGWH--------CQVVACVEGC 1312
Query: 166 ITCNQKPCPRGPCPEPGACCPHCKPGCDYEGQLYEEGVTFLSSSNPCLQCTCLRSRVRCM 225
CP G GAC C++ + G C CTC + C
Sbjct: 1313 F------CPEGTLLHGGACLEPASCPCEWGRNSFPPGSVL---QKDCGNCTCQEGQWHCG 1363
Query: 226 ALKCPPSPCPEPVLRPGHC---CPTCQG----CTEGGSHWEHG-----QEWTTPG---DP 270
GHC P C C E G HG Q+ G +
Sbjct: 1364 G-------------DGGHCEELVPACAEGEALCQENGHCVPHGWLCDNQDDCGDGSDEEG 1410
Query: 271 CRICRCLEGHIQC-------------RQRECASLCPYPARPLP--------GTCCP---V 306
C C EG + C RQ +C P+ P P G C P +
Sbjct: 1411 CAAPGCGEGQMTCSSGHCLPLALLCDRQDDCGDGTDEPSYPCPQGLLACADGRCLPPALL 1470
Query: 307 CDGCFLNGREHRSGEPVGSGDPC-SHCRCANGSVQCEP-------------LPCPPVPCR 352
CDG H + C C G V C CP
Sbjct: 1471 CDG-------HPDCLDAADEESCLGQVTCVPGEVSCVDGTCLGAIQLCDGVWDCPDGADE 1523
Query: 353 HPGKIPGQCCPVCDGCEYQGHQYQSQETFRLQERGLCVRCSCQAGEVSCEEQECPVTPCA 412
PG P P G S +T C E C EC
Sbjct: 1524 GPGHCPLPSLPTPPASTLPGPSPGSLDTASSPLASASPAPPCGPFEFRCGSGEC------ 1577
Query: 413 LPASGRQLCPACELDGEEFAEGVQWEPDGRPCTA--CVCQDGVPKCGAVLCPPAPCQHPT 470
P R C+ + E+ A+G G PC C G P C + P C
Sbjct: 1578 TPRGWR-----CDQE-EDCADGSDERGCGGPCAPHHAPCARG-PHC---VSPEQLCDGVR 1627
Query: 471 QPPGACCPSCDSCTYHSQVYANGQNFTDADSPCHACHCQDGT-VTCSLVDCPPTTCARP- 528
Q P D+C G N T PC C +GT + LV C RP
Sbjct: 1628 QCPDGSDEGPDAC--GGLPALGGPNRTGL--PCPEYTCPNGTCIGFQLVCDGQPDCGRPG 1683
Query: 529 -------QSGPGQCCPRCPDCILEEEVFVDGESFSHPRDP-----CQECRCQEGHAH-CQ 575
+ G G P P G+ S P Q C E + C
Sbjct: 1684 QVGPSPEEQGCGAWGPWSPWGPCSRTCGPWGQGRSRRCSPLGLLVLQNCPGPEHQSQACF 1743
Query: 576 PRPCP-RAPCAHPLPGTCCPNDCSGCAFGGKEYPSGADFPHPSDPCRLCRCLSGNVQCLA 634
CP + P + C C G ++ S P + R C L G +
Sbjct: 1744 TAACPVDGEWSTWSPWSVCSEPCRGTMTRQRQCHS------PQNGGRTCAALPGGLHS-T 1796
Query: 635 RRCVPLP---CPEPVLLPGECCPQCPAAPAPAGCPRPGAAHARHQEYFSPPGDPCRR--C 689
R+ P P CP GE Q P AP P C + PP PC C
Sbjct: 1797 RQTKPCPQDGCPN-ATCSGELMFQ-PCAPCPLTCDDISG------QVTCPPDWPCGSPGC 1848
Query: 690 LCLDGSVSCQRLPCPPAPCAHPRQGPCCPSCDGCLYQGKEFASGERFPSPTAACHLCLCW 749
C +G V C PRQ CP CL G + G+R A C LC+C
Sbjct: 1849 WCPEGQVLGSE-----GWCVWPRQ---CP----CLVDGARYWPGQRI---KADCQLCICQ 1893
Query: 750 EGSVSCEPKACAPALCPFPARGDCCPDC 777
+G P+ C DC DC
Sbjct: 1894 DG----RPRRCR-------LNPDCAVDC 1910
Score = 69.3 bits (168), Expect = 1e-11
Identities = 193/860 (22%), Positives = 252/860 (29%), Gaps = 278/860 (32%)
Query: 114 CTACVCQDGAAHCGPQAHLPHCRGCSQN--------------------GQTYGNGETFSP 153
C + C++G HC P+ H C Q GQ G G+
Sbjct: 3725 CFSEGCEEGC-HC-PEGTFQHRLACVQECPCVLTAWLLQELGATIGDPGQPLGPGDELDS 3782
Query: 154 D-----ACTTCRCLEGTITCNQKPC-----------PRGPC------------------- 178
+C C C G ++C+ C P GPC
Sbjct: 3783 GQTLRTSCGNCSCAHGKLSCSLDDCFEADGGFGPWSPWGPCSRSCGGLGTRTRSRQCVLT 3842
Query: 179 -----------PEPGACCPHCKPGCDYEGQLYEEGVTFL-------SSSNPCLQ-CT--- 216
P CP P C E VT L SS +PC + CT
Sbjct: 3843 MPTLSGQGCRGPRQDLECP--SPDCPGAEGSTVEPVTGLPGGWGPWSSWSPCSRSCTDPA 3900
Query: 217 --CLRSRVRCMALKCPPS------PCPEPVLRPGHCCPTCQGCTEGGSHWEHGQEWTTPG 268
RSR R C PC P CP GC G W W
Sbjct: 3901 RPAWRSRTRLCLANCTMGDPLQERPCNLPSCTELPVCPG-PGCGAGNCSWTSWAPWEPCS 3959
Query: 269 DPCRICR----------------CLEGHIQCRQRECASL--CPYP---ARPLPGTCCPVC 307
C + + C ++R +L CP P +R P + C
Sbjct: 3960 RSCGVGQQRRLRAYRPPGPGGHWCPNILTAYQERRFCNLRACPVPGGWSRWSPWSWCDRS 4019
Query: 308 --DGCFLNGREHRSGEPVGSGDPCSHCRCANGSVQCEPLPCPP----------------- 348
G L R S G PC+ R + + C P+PC
Sbjct: 4020 CGGGQSLRSRSCSSPPSKNGGAPCAGER--HQARLCNPMPCEAGCPAGMEVVTCANRCPR 4077
Query: 349 ------------------VPCRHP-GKIP--GQCCPV--CDGCEYQGHQYQSQETFRLQE 385
CR P G + G C P+ CD + QGH + Q
Sbjct: 4078 RCSDLQEGIVCQDDQVCQKGCRCPKGSLEQDGGCVPIGHCDCTDAQGHSWAPGS----QH 4133
Query: 386 RGLCVRCSCQAGEVSCEEQEC-PVTPCALPASGRQLCPACELDGEEFAEGVQWEPDGRPC 444
+ C CSCQAG++SC Q C P T CA ++ W P C
Sbjct: 4134 QDACNNCSCQAGQLSCTAQPCPPPTHCA------------------WSHWSAWSPCSHSC 4175
Query: 445 ---------TACVCQDGVPKCGAVLCPPAPCQHPTQPPGACCPSCDSCTYHSQVYANGQN 495
+ P+C PC P+ PP C ++ G +
Sbjct: 4176 GPRGQQSRFRSSTSGSWAPECREEQSQSQPCPQPSCPP--------LCLQGTRSRTLGDS 4227
Query: 496 FTDADSPCHACHCQDGTVTCSLVDCPPTTCARPQSGPGQCCPRCPDCILEEEVFVDGESF 555
+ + C C C T V C T CA P++ DC V G +
Sbjct: 4228 WLQGE--CQRCSC-----TPEGVICEDTECAVPEA--WTLWSSWSDC----PVSCGGGNQ 4274
Query: 556 SHPRDPCQECRCQEGHAHCQPRPCPRAPCAHPLPGT---CCPNDCSGCAFG-----GKEY 607
R CR H H P PC P T CP C++G +
Sbjct: 4275 VRTR----ACRAAAPH-HRSP------PCLGPDTQTRQQPCPGLLEACSWGPWGPCSRSC 4323
Query: 608 PSGADFPHPSDPCRLCR----CLSGNVQCLARRCVPLPCPEP---------------VLL 648
G S PC + + C S + + C PCPE VL+
Sbjct: 4324 GPGLASRSGSCPCLMAKADPTCNSTFLHLDTQGCYSGPCPEECVWSSWSSWTRCSCRVLV 4383
Query: 649 PGECCPQCPAA-PAPAGCP--------RPGAAHARHQEYFSPP------GDPCR-RCLCL 692
Q PA+ A AG P RP ++ +PP G PC C
Sbjct: 4384 QQRYRHQGPASRGARAGAPCTRLDGHFRPCLISNCSEDSCTPPFEFHACGSPCAGLCATH 4443
Query: 693 DGSVSCQRL-PCPPAPCAHPR-----QGPCCP--SCD----GCLYQGKEFASGERFPSPT 740
CQ L PC P C P+ G C P C+ G A G+R
Sbjct: 4444 LSHQLCQDLPPCQPG-CYCPKGLLEQAGGCIPPEECNCWHTSAAGAGMTLAPGDRL---Q 4499
Query: 741 AACHLCLCWEGSVSCEPKAC 760
C C C G + C + C
Sbjct: 4500 LGCKECECRRGELHCTSQGC 4519
Score = 57.4 bits (137), Expect = 5e-08
Identities = 141/592 (23%), Positives = 174/592 (29%), Gaps = 154/592 (26%)
Query: 267 PGDPCRICRCLEGHIQCRQRECASL---CPYPARPLPGTCCPVCDGCFLNGREHRSGEPV 323
PG P C + C EC S C G+ C C L P
Sbjct: 2455 PGLPASRALCSPSQLSCGSGECLSAERRCDLRPDCQDGSDEDGCVDCVL--------APW 2506
Query: 324 GSGDPCSHCRCANGSVQCEPLPCPPVPCRHPGKIPGQCCPVCDGCEYQGHQYQSQETF-- 381
CS + Q + L PP +PG CP +++SQ F
Sbjct: 2507 SVWSSCSRSCGLGLTFQRQELLRPP--------LPGGSCP--------RDRFRSQSCFVQ 2550
Query: 382 ---------RLQERGLCVRCSCQAGEVSCEEQECPVTPCALPASGRQLCPACELDGEEFA 432
+ G C SC G S ++ C P P +G CP
Sbjct: 2551 ACPVAGAWAMWEAWGPC-SVSCGGGHQS-RQRSCVDPP---PKNGGAPCPGAS------- 2598
Query: 433 EGVQWEPDGRPCTACVCQDGVP-KCGAVLCPPAPCQHPTQPPGACCPSCDSCTYHSQVYA 491
+ PC C G + G V CQ PP C PSC
Sbjct: 2599 ------QERAPCGLQPCSGGTDCELGRVYVSADLCQKGLVPP--CPPSCLD--------- 2641
Query: 492 NGQNFTDADSPCHACHCQDGTVTCSLVDCPPTTCARPQSGPGQCCP--RCPDCILEEEVF 549
A+ C HC +G CPP +C P CP C++ EE+
Sbjct: 2642 -----PKANRSCSG-HCVEGC------RCPPGLLLHDT----RCLPLSECP-CLVGEELK 2684
Query: 550 VDGESFSHPRDPCQECRCQEGHAHCQPRPCPRAPCAHPLPGTCCPNDCSGCAFGGKEYPS 609
G SF C +C C++G CQP CP PC + P D S C G +
Sbjct: 2685 WPGVSFLLGN--CSQCVCEKGELLCQPGGCP-LPCGWSAWSSWAPCDRS-CGSGVR---- 2736
Query: 610 GADFPHPSDPCRLCRCLSGNVQCLARRCVPLPCP----------EPVLLPGECCPQCPAA 659
A F PS+P G C R C P C C A
Sbjct: 2737 -ARFRSPSNP----PAAWGGAPCEGDRQELQGCHTVCGTEVFGWTPWTSWSSCSQSCLAP 2791
Query: 660 PAPAG-------CPRPG----AAHARHQEYFSPPGDPCRRCLCL-----------DGSV- 696
G CP PG A +E SPP P L DG +
Sbjct: 2792 GGGPGWRSRSRLCPSPGDSSCPGDATQEEPCSPPVCPVPSIWGLWAPWSTCSAPCDGGIQ 2851
Query: 697 ----SCQRLPCPPAPCAHPRQ-------GPCCPSC-DGCLYQGKEFASGERFPSPTAACH 744
SC L C P PC C + L++ E E P P
Sbjct: 2852 TRGRSCSSLAPGDTTCPGPHSQTRDCNTQPCTAQCPENMLFRSAEQCHQEGGPCP----R 2907
Query: 745 LCLCWEGSVSCEPKACAPALCP---FPARGDCCP--DCDGEGHGIGSCRGGM 791
LCL + C CP F C P C + HG G M
Sbjct: 2908 LCLTQGPGIECTGFCAPGCTCPPGLFLHNASCLPRSQCPCQLHGQLYASGAM 2959
Score = 53.1 bits (126), Expect = 1e-06
Identities = 72/264 (27%), Positives = 94/264 (35%), Gaps = 65/264 (24%)
Query: 327 DPCSHCRCANGSV---QCEPLPCPPVPCRH----PGKIPG-----QCCPVCDGCEYQGHQ 374
DP S C C S +C P P R+ P PG +C P C G
Sbjct: 791 DPGSDCLCPVLSAYARRCAQEGASP-PWRNQTLCPVMCPGGQEYRECAPAC------GQH 843
Query: 375 YQSQETFRLQERGLCVR-CSCQAGEVSCEEQECPVTPCALPASGRQLCPACELDGEEFAE 433
E E G CV C+C G + E +C +P S LCP C+L +A
Sbjct: 844 CGKPED--CGELGSCVAGCNCPLGLLWDPEGQC------VPPS---LCP-CQLGARRYAP 891
Query: 434 GVQWEPDGRPCTACVCQD-GVPKCGAVLCPP-APCQHP-TQPPGACCPSCDSCTYHSQVY 490
G + C C+CQ+ G+ C A CP A C PGAC +CDS + +
Sbjct: 892 G---SATMKECNRCICQERGLWNCTARHCPSQAFCPRELVYAPGACLLTCDSPSANHSCP 948
Query: 491 ANGQNFTDADSPCHACHCQDGTVTCSLVDCPPTTCARPQSGPGQCCPRCPDCILEEEVFV 550
A + C C GTV PP C SG P+ ++E+
Sbjct: 949 AGSTD---------GCVCPPGTVLLDERCVPPDLCPCRHSGQWY----LPNATIQED--- 992
Query: 551 DGESFSHPRDPCQECRCQEGHAHC 574
C C C+ HC
Sbjct: 993 -----------CNVCVCRGRQWHC 1005
Score = 52.4 bits (124), Expect = 2e-06
Identities = 66/260 (25%), Positives = 88/260 (33%), Gaps = 80/260 (30%)
Query: 68 MELREQNKDLQ---TRVRQLESCECHPASPQCWGLGRAWPEGARWEPDA----------- 113
+ L EQ ++L R C CH + C + P G W+ A
Sbjct: 4885 LTLEEQAQELPPGTVLTRNCTRCVCHGGAFSCSLVDCQVPPGETWQQVAPGELGLCEQTC 4944
Query: 114 ----------------CTACVCQDG--AAHCGPQAHLPHCRGCSQNGQTYGNGETFSPDA 155
+ CVCQ G + GP HC C G+ + G + +A
Sbjct: 4945 LEMNATKTQSNCSSARASGCVCQPGHFRSQAGPCVPEDHCE-CWHLGRPHLPGSEWQ-EA 5002
Query: 156 CTTCRCLEGTITCNQK----PCPRGP--CPEPGACCPHCK--------PGCDY------- 194
C +C CL G C Q C +G EPG+CCP C+ P C
Sbjct: 5003 CESCLCLSGRPVCTQHCSPLTCAQGEEMVLEPGSCCPSCRREAPEEQSPSCQLLTELRNF 5062
Query: 195 -EGQLYEEGVTFLSSSNPC--------------LQCTCL------RSRVRCMALKCPPSP 233
+G Y + V S C QC C S VR + L+C
Sbjct: 5063 TKGTCYLDQVEVSYCSGYCPSSTHVMPEEPYLQSQCDCCSYRLDPESPVRILNLRCLGGH 5122
Query: 234 CPEPVLRP--GHC-CPTCQG 250
EPV+ P C C +CQG
Sbjct: 5123 -TEPVVLPVIHSCQCSSCQG 5141
Score = 45.8 bits (107), Expect = 2e-04
Identities = 76/309 (24%), Positives = 101/309 (32%), Gaps = 86/309 (27%)
Query: 477 CPSCDS-----CTYHSQVYANGQNFTDADSPCHACHCQDGTVTCSLVDCPPTTCARPQSG 531
CPS DS CT HSQ +A A++ C H LVD P
Sbjct: 734 CPSEDSALLSPCTTHSQRHAF------AEAACAILHSSVFQECHRLVDKEPFYL------ 781
Query: 532 PGQCCPRCPDCILEEEVFVDGESFSHPRDPCQECRCQEGHAHCQPRPCPRAPCAHPLPG- 590
+C C DP +C C A+ R C + + P
Sbjct: 782 --RCLAAVCGC-----------------DPGSDCLCPVLSAYA--RRCAQEGASPPWRNQ 820
Query: 591 TCCPNDCSGCAFGGKEYPS-----GADFPHPSDPCRLCRCLSGNVQCLARRCVPLPCPEP 645
T CP C G G+EY G P D L C++G CP
Sbjct: 821 TLCPVMCPG----GQEYRECAPACGQHCGKPEDCGELGSCVAG-----------CNCPLG 865
Query: 646 VLLP--GECCPQCPAAPAPAGCPRPGAAHARHQEYFSPPGDPCRRCLCLD-GSVSCQRLP 702
+L G+C P P G R A +E C RC+C + G +C
Sbjct: 866 LLWDPEGQCVPPS-LCPCQLGARRYAPGSATMKE--------CNRCICQERGLWNCTARH 916
Query: 703 CPPAPCAHPRQ-----GPCCPSCDGCLYQGKEFASGERFPSPTAACHLCLCWEGSVSCEP 757
CP PR+ G C +CD + P + C+C G+V +
Sbjct: 917 CPSQAFC-PRELVYAPGACLLTCD---------SPSANHSCPAGSTDGCVCPPGTVLLDE 966
Query: 758 KACAPALCP 766
+ P LCP
Sbjct: 967 RCVPPDLCP 975
Score = 45.4 bits (106), Expect = 2e-04
Identities = 96/439 (21%), Positives = 123/439 (28%), Gaps = 108/439 (24%)
Query: 376 QSQETFRLQERGLCVRCSCQAGEVSCEEQECPVTPCALPASGRQLCPACELDGEEFAEGV 435
Q FR + GLC A Q L A +L P C G+
Sbjct: 1133 QLSPQFRGRVAGLCGDFDGDASNDLRSRQGVLEPTAELAAHSWRLSPLCPEPGDL----- 1187
Query: 436 QWEPDGRPCTACVCQDGVPK--CGAVLCPPAPCQHPTQPP---------GAC-CPSCDSC 483
PCT + G + CGA+L P H PP AC C S C
Sbjct: 1188 -----PHPCTMNTHRAGWARARCGALLQPLFTLCHAEVPPQQHYEWCLYDACGCDSGGDC 1242
Query: 484 --------TYHSQVYANGQNFTDADSPCHACHCQDGTVTCSLVDCPPTTCARPQSGPGQC 535
TY + +G + + C+ G V + P TC PG
Sbjct: 1243 ECLCSAIATYADECARHGHHVRWRSQELCSLQCEGGQVYEACGPTCPPTCHEQHPEPGWH 1302
Query: 536 CPRCPDCILEEEVFVDGESFSHPRDPCQECRCQEGHAHCQPRPCPRAPCAHPLP-GTCCP 594
C + C+ E F C E G A +P CP + P G+
Sbjct: 1303 C-QVVACV--EGCF------------CPEGTLLHGGACLEPASCPCEWGRNSFPPGSVLQ 1347
Query: 595 NDCSGCAFGGKEYPSGADFPHPSDPCRLCRCLSGNVQCLAR-RCVPLPCPEPVLLPGECC 653
DC C ++ G D H + + C G C CVP G C
Sbjct: 1348 KDCGNCTCQEGQWHCGGDGGHCEE--LVPACAEGEALCQENGHCVP---------HGWLC 1396
Query: 654 PQ---CPAAPAPAGCPRPGAAHARHQEYFSPPGDPCRRCLCLDGSVSCQRLPCPPAPCAH 710
C GC PG C +G ++C C P
Sbjct: 1397 DNQDDCGDGSDEEGCAAPG---------------------CGEGQMTCSSGHCLPLALLC 1435
Query: 711 PRQGPCCPSCDGCLYQGKEFASGERFPSPTAACHLCLCWEGSVSCEPKACAPALCPFPAR 770
RQ C D Y C +G ++C C P
Sbjct: 1436 DRQDDCGDGTDEPSYP---------------------CPQGLLACADGRCLPPALLCDGH 1474
Query: 771 GDCCPDCDGEGHGIGSCRG 789
DC D E SC G
Sbjct: 1475 PDCLDAADEE-----SCLG 1488
Score = 39.3 bits (90), Expect = 0.015
Identities = 57/203 (28%), Positives = 71/203 (34%), Gaps = 45/203 (22%)
Query: 276 CLEGHIQCRQRE---CASLCPYPARPLPGTCCPVCD-GCFLNGREHRSGEPVGSGDPC-S 330
C HI R R+ C LCP L C +C C G+ GE + C S
Sbjct: 450 CARRHIHIRWRKPGFCERLCP--GGQLYSDCVSLCPPSCEAVGQ----GEEESCREECVS 503
Query: 331 HCRCANGSVQCEPLPCPPVPCRHPGKIPGQCCPVCDGCEYQGHQYQSQETFRLQERGLCV 390
C C G L C VP H CP C Y +Y +T R LC
Sbjct: 504 GCECPRGLFWNGTL-C--VPAAH--------CP----CYYCRQRYVPGDTVRQ----LCN 544
Query: 391 RCSCQAGEVSCEEQECPVTPCALPASGRQLCPACELDGEEFAEGVQWEPDGRPCTACVCQ 450
C C+ G C + CP CA+ G L DG ++ W G+ C + Q
Sbjct: 545 PCVCRDGRWHCAQALCP-AECAVGGDGHYL----TFDGRSYS---FW--GGQGCRYSLVQ 594
Query: 451 DGVPKCGAVL-----CPPAPCQH 468
D V +L C C H
Sbjct: 595 DYVKGQLLILLEHGACDAGSCLH 617
Score = 38.9 bits (89), Expect = 0.019
Identities = 46/194 (23%), Positives = 63/194 (32%), Gaps = 45/194 (23%)
Query: 614 PHPSDPCRLCRCLSGNVQCLARRCVPLPCPEPVLLPGECCPQCPAAPAPAGCPRPGAAHA 673
P P C++ C+ G C CPE LL G C + PA CP ++
Sbjct: 1297 PEPGWHCQVVACVEG---CF--------CPEGTLLHGGACLE------PASCPCEWGRNS 1339
Query: 674 RHQEYFSPPGD----PCRRCLCLDGSVSC--------QRLP-CPPAPCAHPRQGPCCPSC 720
PPG C C C +G C + +P C G C P
Sbjct: 1340 ------FPPGSVLQKDCGNCTCQEGQWHCGGDGGHCEELVPACAEGEALCQENGHCVPH- 1392
Query: 721 DGCLYQGKEFASGERFPSPTAACHLCLCWEGSVSCEPKACAPALCPFPARGDCCPDCDGE 780
G L ++ S C C EG ++C C P + DC D
Sbjct: 1393 -GWLCDNQDDCGDG---SDEEGCAAPGCGEGQMTCSSGHCLPLALLCDRQDDCGDGTDEP 1448
Query: 781 GH----GIGSCRGG 790
+ G+ +C G
Sbjct: 1449 SYPCPQGLLACADG 1462
Score = 38.1 bits (87), Expect = 0.033
Identities = 40/162 (24%), Positives = 53/162 (32%), Gaps = 33/162 (20%)
Query: 88 ECHPAS--PQCWGLGRAWPEGARWEPDACTACVCQDG------AAHCGPQAHLPH----- 134
+C P S P G R P A + C C+CQ+ A HC QA P
Sbjct: 873 QCVPPSLCPCQLGARRYAPGSATMKE--CNRCICQERGLWNCTARHCPSQAFCPRELVYA 930
Query: 135 CRGCSQNGQTYGNGETFSPDACTTCRCLEGTITCNQKPCPRGPCPEPGACCPHCKPGCDY 194
C + + + C C GT+ +++ P CP C +
Sbjct: 931 PGACLLTCDSPSANHSCPAGSTDGCVCPPGTVLLDERCVPPDLCP------------CRH 978
Query: 195 EGQLYEEGVTFLSSSNPCL------QCTCLRSRVRCMALKCP 230
GQ Y T N C+ CT R RC A P
Sbjct: 979 SGQWYLPNATIQEDCNVCVCRGRQWHCTGQRRSGRCQASGAP 1020
Score = 37.0 bits (84), Expect = 0.074
Identities = 30/106 (28%), Positives = 36/106 (33%), Gaps = 19/106 (17%)
Query: 135 CRGCSQNGQTYGNGETFSPDACT--------TCR--CLEGTITCNQKPCPRGPCPEPGAC 184
C GQ Y + + P +C +CR C+ G CPRG C
Sbjct: 465 CERLCPGGQLYSDCVSLCPPSCEAVGQGEEESCREECVSGC------ECPRGLFWNGTLC 518
Query: 185 CPHCKPGCDYEGQLYEEGVTFLSSSNPCLQCTCLRSRVRCMALKCP 230
P C Y Q Y G T NPC+ C R C CP
Sbjct: 519 VPAAHCPCYYCRQRYVPGDTVRQLCNPCV---CRDGRWHCAQALCP 561
Score = 33.1 bits (74), Expect = 1.1
Identities = 32/103 (31%), Positives = 40/103 (38%), Gaps = 23/103 (22%)
Query: 420 LCP-ACELDGEEFAEGVQWEPDGRPCTACVCQDGVPKCGAVLCPPAPCQHPTQPPGACCP 478
LCP +CE G+ E + E + C C G+ G LC PA A CP
Sbjct: 481 LCPPSCEAVGQGEEESCREEC----VSGCECPRGLFWNGT-LCVPA----------AHCP 525
Query: 479 SCDSCTYHSQVYANGQNFTDADSPCHACHCQDGTVTCSLVDCP 521
C Y Q Y G C+ C C+DG C+ CP
Sbjct: 526 ----CYYCRQRYVPGDTVRQL---CNPCVCRDGRWHCAQALCP 561
Score = 32.7 bits (73), Expect = 1.4
Identities = 36/122 (29%), Positives = 42/122 (34%), Gaps = 24/122 (19%)
Query: 594 PNDCSGCAFGGKEYPSGADFPHPSDPCRLCRCLS-GNVQCLARRCVP-LPCPEPVLLPGE 651
P C GG+ Y PS C + G + CV CP + G
Sbjct: 462 PGFCERLCPGGQLYSDCVSLCPPS-----CEAVGQGEEESCREECVSGCECPRGLFWNGT 516
Query: 652 CCPQCPAAPAPAGCPRPGAAHARHQEYFSPPGDP----CRRCLCLDGSVSCQRLPCPPAP 707
C PAA P R Q Y PGD C C+C DG C + C PA
Sbjct: 517 LC--VPAAHCPCYYCR--------QRYV--PGDTVRQLCNPCVCRDGRWHCAQALC-PAE 563
Query: 708 CA 709
CA
Sbjct: 564 CA 565
Score = 32.7 bits (73), Expect = 1.4
Identities = 33/128 (25%), Positives = 42/128 (32%), Gaps = 34/128 (26%)
Query: 170 QKPCPRGPCPEPGACCPHCKPGCDYEGQLYEEGVTFLSSSNPCLQ-CTCLRSRVRCMALK 228
++ CP G C C P C+ GQ EE S C+ C C R L
Sbjct: 466 ERLCPGGQLYSD--CVSLCPPSCEAVGQGEEE-----SCREECVSGCECPRGLFWNGTLC 518
Query: 229 CPPSPCPEPVLRPGHCCPTCQGCTEGGSHWEHGQEWTTPGDP----CRICRCLEGHIQCR 284
P + CP C C ++ PGD C C C +G C
Sbjct: 519 VPAAHCP------------CYYC----------RQRYVPGDTVRQLCNPCVCRDGRWHCA 556
Query: 285 QRECASLC 292
Q C + C
Sbjct: 557 QALCPAEC 564
Score = 32.3 bits (72), Expect = 1.8
Identities = 29/102 (28%), Positives = 37/102 (36%), Gaps = 29/102 (28%)
Query: 508 CQDGTVTCSLVD-CPPTTCARPQSGPGQC---------CPR--------------CPDCI 543
C G + V CPP+ A Q C CPR CP C
Sbjct: 469 CPGGQLYSDCVSLCPPSCEAVGQGEEESCREECVSGCECPRGLFWNGTLCVPAAHCP-CY 527
Query: 544 LEEEVFVDGESFSHPRDPCQECRCQEGHAHCQPRPCPRAPCA 585
+ +V G++ R C C C++G HC CP A CA
Sbjct: 528 YCRQRYVPGDTV---RQLCNPCVCRDGRWHCAQALCP-AECA 565
>gi|221316563 chordin-like 1 isoform 2 precursor [Homo sapiens]
Length = 457
Score = 104 bits (260), Expect = 3e-22
Identities = 84/300 (28%), Positives = 106/300 (35%), Gaps = 61/300 (20%)
Query: 424 CELDGEEFAEGVQWEPDGRP-----CTACVC-QDGVPKCGAVLCPPAPCQHPTQPPGACC 477
C +++ G +W P P C C+C ++G C V CP C P P CC
Sbjct: 37 CMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCC 96
Query: 478 PSCD-------------SCTYHSQVYANGQNFTDAD-------SPCHACHCQDGTVTCSL 517
P C SC Y+ Y +G+ F + C C C +G V C L
Sbjct: 97 PRCPDSLPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCGL 156
Query: 518 VDCPPTTCARPQSGPGQCCPRC-PDCILEEEVFVDGESFSHPRDPCQECRCQEGHAHCQP 576
CP TCA P S P CC C D L E DG+ F P + +E R +H P
Sbjct: 157 KTCPKLTCAFPVSVPDSCCRVCRGDGELSWE-HSDGDIFRQPAN--REARHSYHRSHYDP 213
Query: 577 RPCPRAPCAHPLPGT-------CCPNDCSG----------------CAFGGKEYPSGADF 613
P +A PG SG C GK Y G +
Sbjct: 214 PPSRQAGGLSRFPGARSHRGALMDSQQASGTIVQIVINNKHKHGQVCVSNGKTYSHGESW 273
Query: 614 PHPS------DPCRLCRCLSGNVQCLARRCV-PLPCPEPVLLPGECCPQCPAAPAPAGCP 666
HP+ C LC C +C C PC P + G+CC CP A P
Sbjct: 274 -HPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCCKVCPGKKAKEELP 332
Score = 96.7 bits (239), Expect = 8e-20
Identities = 78/293 (26%), Positives = 106/293 (36%), Gaps = 68/293 (23%)
Query: 138 CSQNGQTYGNGETFSPDA-------CTTCRCLE-GTITCNQKPCPRGPCPEP----GACC 185
C + Y GE + P C C C E G + C++ CP C P CC
Sbjct: 37 CMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCC 96
Query: 186 PHC------------KPGCDYEGQLYEEGVTFLSSS-------NPCLQCTCLRSRVRCMA 226
P C C+Y G Y+ G F++ N C QC+C V C
Sbjct: 97 PRCPDSLPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCGL 156
Query: 227 LKCPPSPCPEPVLRPGHCCPTCQGCTEGGSHWEH--GQEWTTPGD-PCRICRCLEGHIQC 283
CP C PV P CC C+G +G WEH G + P + R +
Sbjct: 157 KTCPKLTCAFPVSVPDSCCRVCRG--DGELSWEHSDGDIFRQPANREARHSYHRSHYDPP 214
Query: 284 RQRECASLCPYP-----------ARPLPGTCCPVC--------DGCFLNGREHRSGEPVG 324
R+ L +P ++ GT + C NG+ + GE
Sbjct: 215 PSRQAGGLSRFPGARSHRGALMDSQQASGTIVQIVINNKHKHGQVCVSNGKTYSHGE--- 271
Query: 325 SGDP---------CSHCRCANGSVQCEPLPCP-PVPCRHPGKIPGQCCPVCDG 367
S P C C C +C+ + CP PC++P KI G+CC VC G
Sbjct: 272 SWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCCKVCPG 324
Score = 89.4 bits (220), Expect = 1e-17
Identities = 88/312 (28%), Positives = 120/312 (38%), Gaps = 60/312 (19%)
Query: 310 CFLNGREHRSGE-------PVGSGDPCSHCRCA-NGSVQCEPLPCPPVPCRHPGKIPGQC 361
C +++R GE P G C +C C+ NG+V C + CP V C P IP C
Sbjct: 37 CMFQDKKYRVGERWHPYLEPYGLVY-CVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLC 95
Query: 362 CPVCD-------------GCEYQGHQYQSQETF------RLQERGLCVRCSCQAGEVSCE 402
CP C CEY G YQ E F + ++ C +CSC G V C
Sbjct: 96 CPRCPDSLPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCG 155
Query: 403 EQECPVTPCALPAS-GRQLCPACELDGE---EFAEG-VQWEPDGRPCTACVCQ---DGVP 454
+ CP CA P S C C DGE E ++G + +P R + D P
Sbjct: 156 LKTCPKLTCAFPVSVPDSCCRVCRGDGELSWEHSDGDIFRQPANREARHSYHRSHYDPPP 215
Query: 455 --KCGAVLCPPAPCQH------PTQPPGACCPSCDSCTY-HSQV-YANGQNFTDADS--- 501
+ G + P H Q G + + H QV +NG+ ++ +S
Sbjct: 216 SRQAGGLSRFPGARSHRGALMDSQQASGTIVQIVINNKHKHGQVCVSNGKTYSHGESWHP 275
Query: 502 --------PCHACHCQDGTVTCSLVDCPPT-TCARPQSGPGQCCPRCPDCILEEEVFVDG 552
C C C C + CP C PQ G+CC CP +EE + G
Sbjct: 276 NLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCCKVCPGKKAKEE--LPG 333
Query: 553 ESFSHPRDPCQE 564
+SF + C E
Sbjct: 334 QSFDNKGYFCGE 345
Score = 81.6 bits (200), Expect = 3e-15
Identities = 70/277 (25%), Positives = 107/277 (38%), Gaps = 58/277 (20%)
Query: 261 GQEWTTPGDP-----CRICRCLE-GHIQCRQRECASL-CPYPARPLPGTCCPVCD----- 308
G+ W +P C C C E G++ C + C ++ C P +P CCP C
Sbjct: 47 GERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVH-IPHLCCPRCPDSLPP 105
Query: 309 --------GCFLNGREHRSGEP-VGSG-------DPCSHCRCANGSVQCEPLPCPPVPCR 352
C NG ++ GE V G + C+ C C+ G+V C CP + C
Sbjct: 106 VNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCGLKTCPKLTCA 165
Query: 353 HPGKIPGQCCPVCDGCEYQGHQYQSQETFR----LQERGLCVRC------SCQAGEVS-- 400
P +P CC VC G ++ + FR + R R S QAG +S
Sbjct: 166 FPVSVPDSCCRVCRGDGELSWEHSDGDIFRQPANREARHSYHRSHYDPPPSRQAGGLSRF 225
Query: 401 ----------CEEQECPVTPCALPASGR-QLCPACELDGEEFAEGVQWEPDGR-----PC 444
+ Q+ T + + + + C +G+ ++ G W P+ R C
Sbjct: 226 PGARSHRGALMDSQQASGTIVQIVINNKHKHGQVCVSNGKTYSHGESWHPNLRAFGIVEC 285
Query: 445 TACVCQDGVPKCGAVLCPPA-PCQHPTQPPGACCPSC 480
C C +C + CP PC++P + G CC C
Sbjct: 286 VLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCCKVC 322
Score = 73.2 bits (178), Expect = 9e-13
Identities = 67/291 (23%), Positives = 97/291 (33%), Gaps = 80/291 (27%)
Query: 96 CWGLGRAWPEGARWEPDA-------CTACVCQDGA-----------AHCGPQAHLPHC-- 135
C + + G RW P C C+C + HC H+PH
Sbjct: 37 CMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCC 96
Query: 136 ----------------RGCSQNGQTYGNGETF---------SPDACTTCRCLEGTITCNQ 170
+ C NG TY +GE F P+ CT C C EG + C
Sbjct: 97 PRCPDSLPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCGL 156
Query: 171 KPCPRGPCPEPGACCPHCKPGCDYEGQL---YEEGVTFLSSSNPCLQCTCLRS------- 220
K CP+ C P + C C +G+L + +G F +N + + RS
Sbjct: 157 KTCPKLTCAFPVSVPDSCCRVCRGDGELSWEHSDGDIFRQPANREARHSYHRSHYDPPPS 216
Query: 221 ---------------RVRCMALKCPPSPCPEPVLRPGHCCPTCQGCTEGGSHWEHGQEW- 264
R M + + V+ H Q C G + HG+ W
Sbjct: 217 RQAGGLSRFPGARSHRGALMDSQQASGTIVQIVINNKH--KHGQVCVSNGKTYSHGESWH 274
Query: 265 ----TTPGDPCRICRCLEGHIQCRQRECASL--CPYPARPLPGTCCPVCDG 309
C +C C +C++ C + C YP + + G CC VC G
Sbjct: 275 PNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQK-IDGKCCKVCPG 324
Score = 70.9 bits (172), Expect = 5e-12
Identities = 72/302 (23%), Positives = 101/302 (33%), Gaps = 76/302 (25%)
Query: 542 CILEEEVFVDGESFSHPRDP-----CQECRCQE-GHAHCQPRPCPRAPCAHP--LPGTCC 593
C+ +++ + GE + +P C C C E G+ C CP C P +P CC
Sbjct: 37 CMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCC 96
Query: 594 PN------------DCSGCAFGGKEYPSGADFP-------HPSDPCRLCRCLSGNVQCLA 634
P C + G Y G F + C C C GNV C
Sbjct: 97 PRCPDSLPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCGL 156
Query: 635 RRCVPLPCPEPVLLPGECCPQCPAAPAPAGCPRPG----------AAHARHQEYFSPPGD 684
+ C L C PV +P CC C + G A H+ H+ ++ PP
Sbjct: 157 KTCPKLTCAFPVSVPDSCCRVCRGDGELSWEHSDGDIFRQPANREARHSYHRSHYDPP-- 214
Query: 685 PCRRCLCLDGSVSCQRLPCPPAPCAHPRQGPCCPSCDG------------------CLYQ 726
P R+ G +S P A +G S C+
Sbjct: 215 PSRQA----GGLS-------RFPGARSHRGALMDSQQASGTIVQIVINNKHKHGQVCVSN 263
Query: 727 GKEFASGERFPSPTAA-----CHLCLCWEGSVSCEPKACAPAL-CPFPAR--GDCCPDCD 778
GK ++ GE + A C LC C C+ C C +P + G CC C
Sbjct: 264 GKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCCKVCP 323
Query: 779 GE 780
G+
Sbjct: 324 GK 325
>gi|221316561 chordin-like 1 isoform 1 precursor [Homo sapiens]
Length = 458
Score = 104 bits (259), Expect = 4e-22
Identities = 84/301 (27%), Positives = 106/301 (35%), Gaps = 62/301 (20%)
Query: 424 CELDGEEFAEGVQWEPDGRP-----CTACVC-QDGVPKCGAVLCPPAPCQHPTQPPGACC 477
C +++ G +W P P C C+C ++G C V CP C P P CC
Sbjct: 37 CMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCC 96
Query: 478 PSCD--------------SCTYHSQVYANGQNFTDAD-------SPCHACHCQDGTVTCS 516
P C SC Y+ Y +G+ F + C C C +G V C
Sbjct: 97 PRCPEDSLPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCG 156
Query: 517 LVDCPPTTCARPQSGPGQCCPRC-PDCILEEEVFVDGESFSHPRDPCQECRCQEGHAHCQ 575
L CP TCA P S P CC C D L E DG+ F P + +E R +H
Sbjct: 157 LKTCPKLTCAFPVSVPDSCCRVCRGDGELSWE-HSDGDIFRQPAN--REARHSYHRSHYD 213
Query: 576 PRPCPRAPCAHPLPGT-------CCPNDCSG----------------CAFGGKEYPSGAD 612
P P +A PG SG C GK Y G
Sbjct: 214 PPPSRQAGGLSRFPGARSHRGALMDSQQASGTIVQIVINNKHKHGQVCVSNGKTYSHGES 273
Query: 613 FPHPS------DPCRLCRCLSGNVQCLARRCV-PLPCPEPVLLPGECCPQCPAAPAPAGC 665
+ HP+ C LC C +C C PC P + G+CC CP A
Sbjct: 274 W-HPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCCKVCPGKKAKEEL 332
Query: 666 P 666
P
Sbjct: 333 P 333
Score = 96.3 bits (238), Expect = 1e-19
Identities = 78/294 (26%), Positives = 106/294 (36%), Gaps = 69/294 (23%)
Query: 138 CSQNGQTYGNGETFSPDA-------CTTCRCLE-GTITCNQKPCPRGPCPEP----GACC 185
C + Y GE + P C C C E G + C++ CP C P CC
Sbjct: 37 CMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCC 96
Query: 186 PHC-------------KPGCDYEGQLYEEGVTFLSSS-------NPCLQCTCLRSRVRCM 225
P C C+Y G Y+ G F++ N C QC+C V C
Sbjct: 97 PRCPEDSLPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCG 156
Query: 226 ALKCPPSPCPEPVLRPGHCCPTCQGCTEGGSHWEH--GQEWTTPGD-PCRICRCLEGHIQ 282
CP C PV P CC C+G +G WEH G + P + R +
Sbjct: 157 LKTCPKLTCAFPVSVPDSCCRVCRG--DGELSWEHSDGDIFRQPANREARHSYHRSHYDP 214
Query: 283 CRQRECASLCPYP-----------ARPLPGTCCPVC--------DGCFLNGREHRSGEPV 323
R+ L +P ++ GT + C NG+ + GE
Sbjct: 215 PPSRQAGGLSRFPGARSHRGALMDSQQASGTIVQIVINNKHKHGQVCVSNGKTYSHGE-- 272
Query: 324 GSGDP---------CSHCRCANGSVQCEPLPCP-PVPCRHPGKIPGQCCPVCDG 367
S P C C C +C+ + CP PC++P KI G+CC VC G
Sbjct: 273 -SWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCCKVCPG 325
Score = 89.0 bits (219), Expect = 2e-17
Identities = 88/313 (28%), Positives = 120/313 (38%), Gaps = 61/313 (19%)
Query: 310 CFLNGREHRSGE-------PVGSGDPCSHCRCA-NGSVQCEPLPCPPVPCRHPGKIPGQC 361
C +++R GE P G C +C C+ NG+V C + CP V C P IP C
Sbjct: 37 CMFQDKKYRVGERWHPYLEPYGLVY-CVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLC 95
Query: 362 CPVCD--------------GCEYQGHQYQSQETF------RLQERGLCVRCSCQAGEVSC 401
CP C CEY G YQ E F + ++ C +CSC G V C
Sbjct: 96 CPRCPEDSLPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYC 155
Query: 402 EEQECPVTPCALPAS-GRQLCPACELDGE---EFAEG-VQWEPDGRPCTACVCQ---DGV 453
+ CP CA P S C C DGE E ++G + +P R + D
Sbjct: 156 GLKTCPKLTCAFPVSVPDSCCRVCRGDGELSWEHSDGDIFRQPANREARHSYHRSHYDPP 215
Query: 454 P--KCGAVLCPPAPCQH------PTQPPGACCPSCDSCTY-HSQV-YANGQNFTDADS-- 501
P + G + P H Q G + + H QV +NG+ ++ +S
Sbjct: 216 PSRQAGGLSRFPGARSHRGALMDSQQASGTIVQIVINNKHKHGQVCVSNGKTYSHGESWH 275
Query: 502 ---------PCHACHCQDGTVTCSLVDCPPT-TCARPQSGPGQCCPRCPDCILEEEVFVD 551
C C C C + CP C PQ G+CC CP +EE +
Sbjct: 276 PNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCCKVCPGKKAKEE--LP 333
Query: 552 GESFSHPRDPCQE 564
G+SF + C E
Sbjct: 334 GQSFDNKGYFCGE 346
Score = 73.6 bits (179), Expect = 7e-13
Identities = 75/307 (24%), Positives = 109/307 (35%), Gaps = 63/307 (20%)
Query: 187 HCKPGCDYEGQLYEEGVTFLSSSNP-----CLQCTCLRS-RVRCMALKCPPSPCPEPVLR 240
H + C ++ + Y G + P C+ C C + V C ++CP C PV
Sbjct: 32 HSETYCMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHI 91
Query: 241 PGHCCPTC--------------QGCTEGGSHWEHGQEWTTPG-------DPCRICRCLEG 279
P CCP C + C G+ ++HG+ + G + C C C EG
Sbjct: 92 PHLCCPRCPEDSLPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEG 151
Query: 280 HIQCRQRECASL-CPYPARPLPGTCCPVCDGCFLNGREHRSG----EPVGSGDPCSHCRC 334
++ C + C L C +P +P +CC VC G EH G +P S+ R
Sbjct: 152 NVYCGLKTCPKLTCAFPV-SVPDSCCRVCRGDGELSWEHSDGDIFRQPANREARHSYHRS 210
Query: 335 ---ANGSVQCEPLPCPPVPCRHPGKI------PGQCCPVC--------DGCEYQGHQYQS 377
S Q L P H G + G + C G Y
Sbjct: 211 HYDPPPSRQAGGLSRFPGARSHRGALMDSQQASGTIVQIVINNKHKHGQVCVSNGKTYSH 270
Query: 378 QETFRLQERGL----CVRCSCQAGEVSCEEQECPVT-PCALPAS-GRQLCPAC------- 424
E++ R CV C+C + C++ CP PC P + C C
Sbjct: 271 GESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCCKVCPGKKAKE 330
Query: 425 ELDGEEF 431
EL G+ F
Sbjct: 331 ELPGQSF 337
Score = 72.8 bits (177), Expect = 1e-12
Identities = 67/292 (22%), Positives = 97/292 (33%), Gaps = 81/292 (27%)
Query: 96 CWGLGRAWPEGARWEPDA-------CTACVCQDGA-----------AHCGPQAHLPHC-- 135
C + + G RW P C C+C + HC H+PH
Sbjct: 37 CMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCC 96
Query: 136 -----------------RGCSQNGQTYGNGETF---------SPDACTTCRCLEGTITCN 169
+ C NG TY +GE F P+ CT C C EG + C
Sbjct: 97 PRCPEDSLPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCG 156
Query: 170 QKPCPRGPCPEPGACCPHCKPGCDYEGQL---YEEGVTFLSSSNPCLQCTCLRS------ 220
K CP+ C P + C C +G+L + +G F +N + + RS
Sbjct: 157 LKTCPKLTCAFPVSVPDSCCRVCRGDGELSWEHSDGDIFRQPANREARHSYHRSHYDPPP 216
Query: 221 ----------------RVRCMALKCPPSPCPEPVLRPGHCCPTCQGCTEGGSHWEHGQEW 264
R M + + V+ H Q C G + HG+ W
Sbjct: 217 SRQAGGLSRFPGARSHRGALMDSQQASGTIVQIVINNKH--KHGQVCVSNGKTYSHGESW 274
Query: 265 -----TTPGDPCRICRCLEGHIQCRQRECASL--CPYPARPLPGTCCPVCDG 309
C +C C +C++ C + C YP + + G CC VC G
Sbjct: 275 HPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQK-IDGKCCKVCPG 325
Score = 70.5 bits (171), Expect = 6e-12
Identities = 72/303 (23%), Positives = 101/303 (33%), Gaps = 77/303 (25%)
Query: 542 CILEEEVFVDGESFSHPRDP-----CQECRCQE-GHAHCQPRPCPRAPCAHP--LPGTCC 593
C+ +++ + GE + +P C C C E G+ C CP C P +P CC
Sbjct: 37 CMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCC 96
Query: 594 PN-------------DCSGCAFGGKEYPSGADFP-------HPSDPCRLCRCLSGNVQCL 633
P C + G Y G F + C C C GNV C
Sbjct: 97 PRCPEDSLPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCG 156
Query: 634 ARRCVPLPCPEPVLLPGECCPQCPAAPAPAGCPRPG----------AAHARHQEYFSPPG 683
+ C L C PV +P CC C + G A H+ H+ ++ PP
Sbjct: 157 LKTCPKLTCAFPVSVPDSCCRVCRGDGELSWEHSDGDIFRQPANREARHSYHRSHYDPP- 215
Query: 684 DPCRRCLCLDGSVSCQRLPCPPAPCAHPRQGPCCPSCDG------------------CLY 725
P R+ G +S P A +G S C+
Sbjct: 216 -PSRQA----GGLS-------RFPGARSHRGALMDSQQASGTIVQIVINNKHKHGQVCVS 263
Query: 726 QGKEFASGERFPSPTAA-----CHLCLCWEGSVSCEPKACAPAL-CPFPAR--GDCCPDC 777
GK ++ GE + A C LC C C+ C C +P + G CC C
Sbjct: 264 NGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCCKVC 323
Query: 778 DGE 780
G+
Sbjct: 324 PGK 326
>gi|34147715 chordin-like 1 isoform 3 precursor [Homo sapiens]
Length = 456
Score = 103 bits (258), Expect = 5e-22
Identities = 83/295 (28%), Positives = 105/295 (35%), Gaps = 61/295 (20%)
Query: 424 CELDGEEFAEGVQWEPDGRP-----CTACVC-QDGVPKCGAVLCPPAPCQHPTQPPGACC 477
C +++ G +W P P C C+C ++G C V CP C P P CC
Sbjct: 37 CMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCC 96
Query: 478 PSCD-------------SCTYHSQVYANGQNFTDAD-------SPCHACHCQDGTVTCSL 517
P C SC Y+ Y +G+ F + C C C +G V C L
Sbjct: 97 PRCPDSLPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCGL 156
Query: 518 VDCPPTTCARPQSGPGQCCPRC-PDCILEEEVFVDGESFSHPRDPCQECRCQEGHAHCQP 576
CP TCA P S P CC C D L E DG+ F P + +E R +H P
Sbjct: 157 KTCPKLTCAFPVSVPDSCCRVCRGDGELSWE-HSDGDIFRQPAN--REARHSYHRSHYDP 213
Query: 577 RPCPRAPCAHPLPGT-------CCPNDCSG----------------CAFGGKEYPSGADF 613
P +A PG SG C GK Y G +
Sbjct: 214 PPSRQAGGLSRFPGARSHRGALMDSQQASGTIVQIVINNKHKHGQVCVSNGKTYSHGESW 273
Query: 614 PHPS------DPCRLCRCLSGNVQCLARRCV-PLPCPEPVLLPGECCPQCPAAPA 661
HP+ C LC C +C C PC P + G+CC CP A
Sbjct: 274 -HPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCCKVCPGKKA 327
Score = 96.7 bits (239), Expect = 8e-20
Identities = 78/293 (26%), Positives = 106/293 (36%), Gaps = 68/293 (23%)
Query: 138 CSQNGQTYGNGETFSPDA-------CTTCRCLE-GTITCNQKPCPRGPCPEP----GACC 185
C + Y GE + P C C C E G + C++ CP C P CC
Sbjct: 37 CMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCC 96
Query: 186 PHC------------KPGCDYEGQLYEEGVTFLSSS-------NPCLQCTCLRSRVRCMA 226
P C C+Y G Y+ G F++ N C QC+C V C
Sbjct: 97 PRCPDSLPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCGL 156
Query: 227 LKCPPSPCPEPVLRPGHCCPTCQGCTEGGSHWEH--GQEWTTPGD-PCRICRCLEGHIQC 283
CP C PV P CC C+G +G WEH G + P + R +
Sbjct: 157 KTCPKLTCAFPVSVPDSCCRVCRG--DGELSWEHSDGDIFRQPANREARHSYHRSHYDPP 214
Query: 284 RQRECASLCPYP-----------ARPLPGTCCPVC--------DGCFLNGREHRSGEPVG 324
R+ L +P ++ GT + C NG+ + GE
Sbjct: 215 PSRQAGGLSRFPGARSHRGALMDSQQASGTIVQIVINNKHKHGQVCVSNGKTYSHGE--- 271
Query: 325 SGDP---------CSHCRCANGSVQCEPLPCP-PVPCRHPGKIPGQCCPVCDG 367
S P C C C +C+ + CP PC++P KI G+CC VC G
Sbjct: 272 SWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCCKVCPG 324
Score = 87.0 bits (214), Expect = 6e-17
Identities = 87/312 (27%), Positives = 119/312 (38%), Gaps = 61/312 (19%)
Query: 310 CFLNGREHRSGE-------PVGSGDPCSHCRCA-NGSVQCEPLPCPPVPCRHPGKIPGQC 361
C +++R GE P G C +C C+ NG+V C + CP V C P IP C
Sbjct: 37 CMFQDKKYRVGERWHPYLEPYGLVY-CVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLC 95
Query: 362 CPVCD-------------GCEYQGHQYQSQETF------RLQERGLCVRCSCQAGEVSCE 402
CP C CEY G YQ E F + ++ C +CSC G V C
Sbjct: 96 CPRCPDSLPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCG 155
Query: 403 EQECPVTPCALPAS-GRQLCPACELDGE---EFAEG-VQWEPDGRPCTACVCQ---DGVP 454
+ CP CA P S C C DGE E ++G + +P R + D P
Sbjct: 156 LKTCPKLTCAFPVSVPDSCCRVCRGDGELSWEHSDGDIFRQPANREARHSYHRSHYDPPP 215
Query: 455 --KCGAVLCPPAPCQH------PTQPPGACCPSCDSCTY-HSQV-YANGQNFTDADS--- 501
+ G + P H Q G + + H QV +NG+ ++ +S
Sbjct: 216 SRQAGGLSRFPGARSHRGALMDSQQASGTIVQIVINNKHKHGQVCVSNGKTYSHGESWHP 275
Query: 502 --------PCHACHCQDGTVTCSLVDCPPT-TCARPQSGPGQCCPRCPDCILEEEVFVDG 552
C C C C + CP C PQ G+CC CP +E + G
Sbjct: 276 NLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCCKVCPGKKAKE---LPG 332
Query: 553 ESFSHPRDPCQE 564
+SF + C E
Sbjct: 333 QSFDNKGYFCGE 344
Score = 81.6 bits (200), Expect = 3e-15
Identities = 70/277 (25%), Positives = 107/277 (38%), Gaps = 58/277 (20%)
Query: 261 GQEWTTPGDP-----CRICRCLE-GHIQCRQRECASL-CPYPARPLPGTCCPVCD----- 308
G+ W +P C C C E G++ C + C ++ C P +P CCP C
Sbjct: 47 GERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVH-IPHLCCPRCPDSLPP 105
Query: 309 --------GCFLNGREHRSGEP-VGSG-------DPCSHCRCANGSVQCEPLPCPPVPCR 352
C NG ++ GE V G + C+ C C+ G+V C CP + C
Sbjct: 106 VNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCGLKTCPKLTCA 165
Query: 353 HPGKIPGQCCPVCDGCEYQGHQYQSQETFR----LQERGLCVRC------SCQAGEVS-- 400
P +P CC VC G ++ + FR + R R S QAG +S
Sbjct: 166 FPVSVPDSCCRVCRGDGELSWEHSDGDIFRQPANREARHSYHRSHYDPPPSRQAGGLSRF 225
Query: 401 ----------CEEQECPVTPCALPASGR-QLCPACELDGEEFAEGVQWEPDGR-----PC 444
+ Q+ T + + + + C +G+ ++ G W P+ R C
Sbjct: 226 PGARSHRGALMDSQQASGTIVQIVINNKHKHGQVCVSNGKTYSHGESWHPNLRAFGIVEC 285
Query: 445 TACVCQDGVPKCGAVLCPPA-PCQHPTQPPGACCPSC 480
C C +C + CP PC++P + G CC C
Sbjct: 286 VLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCCKVC 322
Score = 73.2 bits (178), Expect = 9e-13
Identities = 67/291 (23%), Positives = 97/291 (33%), Gaps = 80/291 (27%)
Query: 96 CWGLGRAWPEGARWEPDA-------CTACVCQDGA-----------AHCGPQAHLPHC-- 135
C + + G RW P C C+C + HC H+PH
Sbjct: 37 CMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCC 96
Query: 136 ----------------RGCSQNGQTYGNGETF---------SPDACTTCRCLEGTITCNQ 170
+ C NG TY +GE F P+ CT C C EG + C
Sbjct: 97 PRCPDSLPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCGL 156
Query: 171 KPCPRGPCPEPGACCPHCKPGCDYEGQL---YEEGVTFLSSSNPCLQCTCLRS------- 220
K CP+ C P + C C +G+L + +G F +N + + RS
Sbjct: 157 KTCPKLTCAFPVSVPDSCCRVCRGDGELSWEHSDGDIFRQPANREARHSYHRSHYDPPPS 216
Query: 221 ---------------RVRCMALKCPPSPCPEPVLRPGHCCPTCQGCTEGGSHWEHGQEW- 264
R M + + V+ H Q C G + HG+ W
Sbjct: 217 RQAGGLSRFPGARSHRGALMDSQQASGTIVQIVINNKH--KHGQVCVSNGKTYSHGESWH 274
Query: 265 ----TTPGDPCRICRCLEGHIQCRQRECASL--CPYPARPLPGTCCPVCDG 309
C +C C +C++ C + C YP + + G CC VC G
Sbjct: 275 PNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQK-IDGKCCKVCPG 324
Score = 70.9 bits (172), Expect = 5e-12
Identities = 72/302 (23%), Positives = 101/302 (33%), Gaps = 76/302 (25%)
Query: 542 CILEEEVFVDGESFSHPRDP-----CQECRCQE-GHAHCQPRPCPRAPCAHP--LPGTCC 593
C+ +++ + GE + +P C C C E G+ C CP C P +P CC
Sbjct: 37 CMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCC 96
Query: 594 PN------------DCSGCAFGGKEYPSGADFP-------HPSDPCRLCRCLSGNVQCLA 634
P C + G Y G F + C C C GNV C
Sbjct: 97 PRCPDSLPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCGL 156
Query: 635 RRCVPLPCPEPVLLPGECCPQCPAAPAPAGCPRPG----------AAHARHQEYFSPPGD 684
+ C L C PV +P CC C + G A H+ H+ ++ PP
Sbjct: 157 KTCPKLTCAFPVSVPDSCCRVCRGDGELSWEHSDGDIFRQPANREARHSYHRSHYDPP-- 214
Query: 685 PCRRCLCLDGSVSCQRLPCPPAPCAHPRQGPCCPSCDG------------------CLYQ 726
P R+ G +S P A +G S C+
Sbjct: 215 PSRQA----GGLS-------RFPGARSHRGALMDSQQASGTIVQIVINNKHKHGQVCVSN 263
Query: 727 GKEFASGERFPSPTAA-----CHLCLCWEGSVSCEPKACAPAL-CPFPAR--GDCCPDCD 778
GK ++ GE + A C LC C C+ C C +P + G CC C
Sbjct: 264 GKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCCKVCP 323
Query: 779 GE 780
G+
Sbjct: 324 GK 325
Score = 41.6 bits (96), Expect = 0.003
Identities = 26/81 (32%), Positives = 36/81 (44%), Gaps = 14/81 (17%)
Query: 134 HCRGCSQNGQTYGNGETFSPD-------ACTTCRCLEGTITCNQKPCP-RGPCPEP---- 181
H + C NG+TY +GE++ P+ C C C C + CP R PC P
Sbjct: 256 HGQVCVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKID 315
Query: 182 GACCPHC--KPGCDYEGQLYE 200
G CC C K + GQ ++
Sbjct: 316 GKCCKVCPGKKAKELPGQSFD 336
>gi|30089980 chordin [Homo sapiens]
Length = 955
Score = 96.3 bits (238), Expect = 1e-19
Identities = 87/306 (28%), Positives = 108/306 (35%), Gaps = 83/306 (27%)
Query: 424 CELDGEEF----AEGVQWEPDGRPCTACVCQDGVPKCGAVLCPPAPCQHPTQPPGACCP- 478
CE+ G AEGV+ G P TA VP P P +P G P
Sbjct: 651 CEVGGLRLEAAGAEGVR--ALGAPDTASAAPPVVPGL--------PALAPAKPGGPGRPR 700
Query: 479 SCDSCTYHSQVYANGQNFTDADSP-CHACHCQDGTVTCSLVDCPPTTCARPQSGPGQCCP 537
++C + Q +G + P C C CQ TV C V CPP +C P P QCCP
Sbjct: 701 DPNTCFFEGQQRPHGARWAPNYDPLCSLCTCQRRTVICDPVVCPPPSCPHPVQAPDQCCP 760
Query: 538 RCPDCILEEEVFVDGESFSHPRDP------------------------------CQECRC 567
CP E++ D RDP C C C
Sbjct: 761 VCP----EKQDVRDLPGLPRSRDPGEGCYFDGDRSWRAAGTRWHPVVPPFGLIKCAVCTC 816
Query: 568 Q--EGHAHCQPRPCPRAPCAHPL---PGTCC------------------PNDCSGCAFGG 604
+ G HC+ CPR CA P+ P CC + GC F G
Sbjct: 817 KGGTGEVHCEKVQCPRLACAQPVRVNPTDCCKQCPVGSGAHPQLGDPMQADGPRGCRFAG 876
Query: 605 KEYPSGADFPHPSDP------CRLCRCLSGNVQCLARRC-VPLPCPEPVLLPGECCPQCP 657
+ +P + HPS P C CRC +G C C +PL C CC +C
Sbjct: 877 QWFPESQSW-HPSVPPFGEMSCITCRCGAGVPHCERDDCSLPLSCGSG--KESRCCSRCT 933
Query: 658 AAPAPA 663
A PA
Sbjct: 934 AHRRPA 939
Score = 89.0 bits (219), Expect = 2e-17
Identities = 77/258 (29%), Positives = 92/258 (35%), Gaps = 52/258 (20%)
Query: 572 AHCQPRPCPRAPCAHPLP--GTCCPNDCSGCAFGGKEYPSGADFPHPSDP-CRLCRCLSG 628
A P P P P G P D + C F G++ P GA + DP C LC C
Sbjct: 675 ASAAPPVVPGLPALAPAKPGGPGRPRDPNTCFFEGQQRPHGARWAPNYDPLCSLCTCQRR 734
Query: 629 NVQCLARRCVPLPCPEPVLLPGECCPQCPAAPAP---AGCPR---PG------------A 670
V C C P CP PV P +CCP CP G PR PG A
Sbjct: 735 TVICDPVVCPPPSCPHPVQAPDQCCPVCPEKQDVRDLPGLPRSRDPGEGCYFDGDRSWRA 794
Query: 671 AHARHQEYFSPPG-DPCRRCLCLDGS--VSCQRLPCPPAPCAHP-RQGP--CCPSCD--- 721
A R P G C C C G+ V C+++ CP CA P R P CC C
Sbjct: 795 AGTRWHPVVPPFGLIKCAVCTCKGGTGEVHCEKVQCPRLACAQPVRVNPTDCCKQCPVGS 854
Query: 722 ----------------GCLYQGKEFASGERF-----PSPTAACHLCLCWEGSVSCEPKAC 760
GC + G+ F + + P +C C C G CE C
Sbjct: 855 GAHPQLGDPMQADGPRGCRFAGQWFPESQSWHPSVPPFGEMSCITCRCGAGVPHCERDDC 914
Query: 761 A-PALCPFPARGDCCPDC 777
+ P C CC C
Sbjct: 915 SLPLSCGSGKESRCCSRC 932
Score = 88.2 bits (217), Expect = 3e-17
Identities = 66/229 (28%), Positives = 83/229 (36%), Gaps = 59/229 (25%)
Query: 310 CFLNGREHRSGEPVGSG-DP-CSHCRCANGSVQCEPLPCPPVPCRHPGKIPGQCCPVC-- 365
CF G++ G DP CS C C +V C+P+ CPP C HP + P QCCPVC
Sbjct: 705 CFFEGQQRPHGARWAPNYDPLCSLCTCQRRTVICDPVVCPPPSCPHPVQAPDQCCPVCPE 764
Query: 366 -----------------DGCEYQGHQYQSQETFR----LQERGL--CVRCSCQ--AGEVS 400
+GC + G + R + GL C C+C+ GEV
Sbjct: 765 KQDVRDLPGLPRSRDPGEGCYFDGDRSWRAAGTRWHPVVPPFGLIKCAVCTCKGGTGEVH 824
Query: 401 CEEQECPVTPCALPASGR-----QLCP-------------------ACELDGEEFAEGVQ 436
CE+ +CP CA P + CP C G+ F E
Sbjct: 825 CEKVQCPRLACAQPVRVNPTDCCKQCPVGSGAHPQLGDPMQADGPRGCRFAGQWFPESQS 884
Query: 437 WEPDGRP-----CTACVCQDGVPKCGAVLCPPAPCQHPTQPPGACCPSC 480
W P P C C C GVP C C P + CC C
Sbjct: 885 WHPSVPPFGEMSCITCRCGAGVPHCERDDC-SLPLSCGSGKESRCCSRC 932
Score = 85.9 bits (211), Expect = 1e-16
Identities = 73/250 (29%), Positives = 95/250 (38%), Gaps = 53/250 (21%)
Query: 521 PPTTCARPQSGPGQCCPRCPD-CILEEEVFVDGESFSHPRDP-CQECRCQEGHAHCQPRP 578
P A+P GPG+ PR P+ C E + G ++ DP C C CQ C P
Sbjct: 686 PALAPAKP-GGPGR--PRDPNTCFFEGQQRPHGARWAPNYDPLCSLCTCQRRTVICDPVV 742
Query: 579 CPRAPCAHPL--PGTCCP------------------NDCSGCAF-GGKEYPSGADFPHPS 617
CP C HP+ P CCP + GC F G + + + HP
Sbjct: 743 CPPPSCPHPVQAPDQCCPVCPEKQDVRDLPGLPRSRDPGEGCYFDGDRSWRAAGTRWHPV 802
Query: 618 DP------CRLCRCL--SGNVQCLARRCVPLPCPEPVLL-PGECCPQCPA---------- 658
P C +C C +G V C +C L C +PV + P +CC QCP
Sbjct: 803 VPPFGLIKCAVCTCKGGTGEVHCEKVQCPRLACAQPVRVNPTDCCKQCPVGSGAHPQLGD 862
Query: 659 ---APAPAGCPRPGAAHARHQEY---FSPPGD-PCRRCLCLDGSVSCQRLPCP-PAPCAH 710
A P GC G Q + P G+ C C C G C+R C P C
Sbjct: 863 PMQADGPRGCRFAGQWFPESQSWHPSVPPFGEMSCITCRCGAGVPHCERDDCSLPLSCGS 922
Query: 711 PRQGPCCPSC 720
++ CC C
Sbjct: 923 GKESRCCSRC 932
Score = 84.0 bits (206), Expect = 5e-16
Identities = 70/282 (24%), Positives = 91/282 (32%), Gaps = 73/282 (25%)
Query: 177 PCPEPGACCPHCKPGCDYEGQLYEEGVTFLSSSNP-CLQCTCLRSRVRCMALKCPPSPCP 235
P G P C +EGQ G + + +P C CTC R V C + CPP CP
Sbjct: 690 PAKPGGPGRPRDPNTCFFEGQQRPHGARWAPNYDPLCSLCTCQRRTVICDPVVCPPPSCP 749
Query: 236 EPVLRPGHCCPTC-------------------QGC-TEGGSHWE-HGQEWTTPGDP---- 270
PV P CCP C +GC +G W G W P
Sbjct: 750 HPVQAPDQCCPVCPEKQDVRDLPGLPRSRDPGEGCYFDGDRSWRAAGTRWHPVVPPFGLI 809
Query: 271 -CRICRCL--EGHIQCRQRECASL-CPYPARPLPGTCCPVCDGCFLNGREHRSGEPVGSG 326
C +C C G + C + +C L C P R P CC C PVGSG
Sbjct: 810 KCAVCTCKGGTGEVHCEKVQCPRLACAQPVRVNPTDCCKQC--------------PVGSG 855
Query: 327 DPCSHCRCANGSVQCEPLPCPPVPCRHPGKIPGQCCPVCDGCEYQGHQYQSQETFRLQER 386
P P+ P GC + G + +++
Sbjct: 856 --------------AHPQLGDPMQADGP-----------RGCRFAGQWFPESQSWHPSVP 890
Query: 387 GL----CVRCSCQAGEVSCEEQECPVTPCALPASGRQLCPAC 424
C+ C C AG CE +C + + C C
Sbjct: 891 PFGEMSCITCRCGAGVPHCERDDCSLPLSCGSGKESRCCSRC 932
Score = 65.5 bits (158), Expect = 2e-10
Identities = 62/250 (24%), Positives = 81/250 (32%), Gaps = 67/250 (26%)
Query: 138 CSQNGQTYGNGETFSPD---ACTTCRCLEGTITCNQKPCPRGPCPE----PGACCPHCK- 189
C GQ +G ++P+ C+ C C T+ C+ CP CP P CCP C
Sbjct: 705 CFFEGQQRPHGARWAPNYDPLCSLCTCQRRTVICDPVVCPPPSCPHPVQAPDQCCPVCPE 764
Query: 190 -----------------PGCDYEG-QLYEEGVTFLSSSNP------CLQCTCL--RSRVR 223
GC ++G + + T P C CTC V
Sbjct: 765 KQDVRDLPGLPRSRDPGEGCYFDGDRSWRAAGTRWHPVVPPFGLIKCAVCTCKGGTGEVH 824
Query: 224 CMALKCPPSPCPEPV-LRPGHCCPTC-------------------QGCTEGGSHWEHGQE 263
C ++CP C +PV + P CC C +GC G + Q
Sbjct: 825 CEKVQCPRLACAQPVRVNPTDCCKQCPVGSGAHPQLGDPMQADGPRGCRFAGQWFPESQS 884
Query: 264 WTTPGDP-----CRICRCLEGHIQCRQRECASLCPYPARPLPGTCCPVCDGCFLNGREHR 318
W P C CRC G C + +C SL CC C HR
Sbjct: 885 WHPSVPPFGEMSCITCRCGAGVPHCERDDC-SLPLSCGSGKESRCCSRCTA-------HR 936
Query: 319 SGEPVGSGDP 328
P DP
Sbjct: 937 RPAPETRTDP 946
Score = 52.0 bits (123), Expect = 2e-06
Identities = 33/113 (29%), Positives = 45/113 (39%), Gaps = 18/113 (15%)
Query: 483 CTYHSQVYANGQNF-TDADSP-----CHACHCQ----------DGTVTCSLV--DCPPTT 524
CT+ +VYA + + D P C C C+ G V+C + +CP
Sbjct: 51 CTFGGKVYALDETWHPDLGEPFGVMRCVLCACEAPQWGRRTRGPGRVSCKNIKPECPTPA 110
Query: 525 CARPQSGPGQCCPRCPDCILEEEVFVDGESFSHPRDPCQECRCQEGHAHCQPR 577
C +P+ PG CC CP E G SF +PRDP G + R
Sbjct: 111 CGQPRQLPGHCCQTCPQERSSSERQPSGLSFEYPRDPEHRSYSDRGEPGAEER 163
Score = 43.1 bits (100), Expect = 0.001
Identities = 35/115 (30%), Positives = 46/115 (40%), Gaps = 25/115 (21%)
Query: 643 PEPVLLPGECCPQCPAAPAPAGCPRPGAAHARHQEYFSPPGDP-----CRRCLCL----- 692
PEP +LP + AGC G +A + + G+P C C C
Sbjct: 29 PEPPVLPIRSEKEPLPVRGAAGCTFGGKVYALDETWHPDLGEPFGVMRCVLCACEAPQWG 88
Query: 693 -----DGSVSCQRLP--CPPAPCAHPRQ--GPCCPSCDGCLYQGKEFASGERFPS 738
G VSC+ + CP C PRQ G CC +C +E +S ER PS
Sbjct: 89 RRTRGPGRVSCKNIKPECPTPACGQPRQLPGHCCQTCP------QERSSSERQPS 137
Score = 43.1 bits (100), Expect = 0.001
Identities = 36/130 (27%), Positives = 45/130 (34%), Gaps = 26/130 (20%)
Query: 405 ECPVTPCA-----LPASGRQLCPACELDGEEFAEGVQWEPD-GRP-----CTACVCQ--- 450
E PV P LP G C G+ +A W PD G P C C C+
Sbjct: 30 EPPVLPIRSEKEPLPVRG---AAGCTFGGKVYALDETWHPDLGEPFGVMRCVLCACEAPQ 86
Query: 451 -------DGVPKCGAVL--CPPAPCQHPTQPPGACCPSCDSCTYHSQVYANGQNFTDADS 501
G C + CP C P Q PG CC +C S+ +G +F
Sbjct: 87 WGRRTRGPGRVSCKNIKPECPTPACGQPRQLPGHCCQTCPQERSSSERQPSGLSFEYPRD 146
Query: 502 PCHACHCQDG 511
P H + G
Sbjct: 147 PEHRSYSDRG 156
Score = 42.4 bits (98), Expect = 0.002
Identities = 31/112 (27%), Positives = 39/112 (34%), Gaps = 24/112 (21%)
Query: 177 PCPEPGACCPHCKPGCDYEGQLYEEGVTFLSSSNP------CLQCTCLR----------S 220
P P GA GC + G++Y T+ C+ C C
Sbjct: 42 PLPVRGAA------GCTFGGKVYALDETWHPDLGEPFGVMRCVLCACEAPQWGRRTRGPG 95
Query: 221 RVRCMALK--CPPSPCPEPVLRPGHCCPTCQGCTEGGSHWEHGQEWTTPGDP 270
RV C +K CP C +P PGHCC TC G + P DP
Sbjct: 96 RVSCKNIKPECPTPACGQPRQLPGHCCQTCPQERSSSERQPSGLSFEYPRDP 147
Score = 42.0 bits (97), Expect = 0.002
Identities = 38/134 (28%), Positives = 49/134 (36%), Gaps = 28/134 (20%)
Query: 575 QPRPCPRAPCAHPLPGTCCPNDCSGCAFGGKEYPSGADF-PHPSDP-----CRLCRCLS- 627
+P P PLP +GC FGGK Y + P +P C LC C +
Sbjct: 30 EPPVLPIRSEKEPLP----VRGAAGCTFGGKVYALDETWHPDLGEPFGVMRCVLCACEAP 85
Query: 628 ---------GNVQC--LARRCVPLPCPEPVLLPGECCPQCP-----AAPAPAGCPRPGAA 671
G V C + C C +P LPG CC CP + P+G
Sbjct: 86 QWGRRTRGPGRVSCKNIKPECPTPACGQPRQLPGHCCQTCPQERSSSERQPSGLSFEYPR 145
Query: 672 HARHQEYFSPPGDP 685
H+ Y S G+P
Sbjct: 146 DPEHRSY-SDRGEP 158
Score = 35.8 bits (81), Expect = 0.16
Identities = 28/95 (29%), Positives = 35/95 (36%), Gaps = 20/95 (21%)
Query: 137 GCSQNGQTYGNGETFSPD--------ACTTCRCL----------EGTITC-NQKP-CPRG 176
GC+ G+ Y ET+ PD C C C G ++C N KP CP
Sbjct: 50 GCTFGGKVYALDETWHPDLGEPFGVMRCVLCACEAPQWGRRTRGPGRVSCKNIKPECPTP 109
Query: 177 PCPEPGACCPHCKPGCDYEGQLYEEGVTFLSSSNP 211
C +P HC C E E + LS P
Sbjct: 110 ACGQPRQLPGHCCQTCPQERSSSERQPSGLSFEYP 144
Score = 33.9 bits (76), Expect = 0.62
Identities = 23/78 (29%), Positives = 31/78 (39%), Gaps = 22/78 (28%)
Query: 250 GCTEGGSHWEHGQEWTTP-GDPCRICRCL---------------EGHIQCRQRECASLCP 293
GCT GG + + W G+P + RC+ G + C+ + CP
Sbjct: 50 GCTFGGKVYALDETWHPDLGEPFGVMRCVLCACEAPQWGRRTRGPGRVSCKNIKPE--CP 107
Query: 294 YPA----RPLPGTCCPVC 307
PA R LPG CC C
Sbjct: 108 TPACGQPRQLPGHCCQTC 125
Score = 32.7 bits (73), Expect = 1.4
Identities = 19/58 (32%), Positives = 23/58 (39%), Gaps = 13/58 (22%)
Query: 320 GEPVGSGDPCSHCRC----------ANGSVQCEPLP--CPPVPCRHPGKIPGQCCPVC 365
GEP G C C C G V C+ + CP C P ++PG CC C
Sbjct: 69 GEPFGVMR-CVLCACEAPQWGRRTRGPGRVSCKNIKPECPTPACGQPRQLPGHCCQTC 125
>gi|38490568 keratin associated protein 10-4 [Homo sapiens]
Length = 401
Score = 86.7 bits (213), Expect = 8e-17
Identities = 110/450 (24%), Positives = 145/450 (32%), Gaps = 85/450 (18%)
Query: 288 CASLCPYPARP-LPGTCCPVCDGCFLNGREHRSGEPVGSGDPCSHCRCANGSVQCEPLPC 346
C+S Y +R LPG+C D ++ EP PC C C P PC
Sbjct: 4 CSSDLSYSSRVCLPGSCDSCSDSWQVDDCPESCCEP-----PCCAPSC------CAPAPC 52
Query: 347 PPVPCRHPGKIPGQCCPV-CDGCEYQGHQYQSQETFRLQERGLCVRCSCQAGEVSCEEQE 405
+ C ++ CCPV C+ Q S C CQ + SC+
Sbjct: 53 LSLVCTPVSRVSSPCCPVTCEPSPCQSGCTSS-----------CTPSCCQ--QSSCQLAC 99
Query: 406 CPVTP----CALPASGRQLC--PACELDGEEFAEGVQWEPDGRPCTACVCQDG----VPK 455
C +P C +P + +C P C C C D
Sbjct: 100 CASSPCQQACCVPVCCKTVCCKPVC-------------------CVPVCCGDSSCCQQSS 140
Query: 456 CGAVLCPPAPCQHPTQPPGACCPSC----DSCTYHSQVYANGQNFTDADSPCHACHCQDG 511
C + C +PCQ P C P C SC S + + + C CQ G
Sbjct: 141 CQSACCTSSPCQQACCVPICCKPVCSGISSSCCQQSSC-VSCVSSPCCQAVCEPSPCQSG 199
Query: 512 TVT------CSLVDCPPTTCARPQSGPGQCCPRCPDCILEEEVFVDGESFSHPRDPCQEC 565
++ C C P C C P C + + V + S CQ+
Sbjct: 200 CISSCTPSCCQQSSCQPACCTSSSCQQACCVPVCCKTVCCKPVCSEDSS-----SCCQQS 254
Query: 566 RCQEGHAHCQPRPCPRAPCAHPLPGTCCPNDCSGCAFGGKEYPSGA-DFPHPSDPCRLCR 624
CQ A C PC +A C +P C P C G SGA C+
Sbjct: 255 SCQP--ACCTSSPCQQACC---VPVCCKPVCCK--PVGSVPICSGASSLCCQQSSCQPAC 307
Query: 625 CLSGNVQ---CLARRCVPLPC-PEPVLLPGECCPQ--CPAAPAPAGCPRPGAAHARHQEY 678
C S Q C+ C P+ C P CC Q C A C RP ++ +
Sbjct: 308 CTSSQSQQGCCVPVCCKPVSCVPVCSGASSSCCQQSSCQPACCTTSCCRPSSSVSLLCRP 367
Query: 679 FSPPGDPCRRCLCLDGSVSCQRLPCPPAPC 708
P C + SCQ C PA C
Sbjct: 368 VCRPACCVPVPSCCAPTSSCQPSCCRPASC 397
Score = 80.5 bits (197), Expect = 6e-15
Identities = 103/409 (25%), Positives = 133/409 (32%), Gaps = 58/409 (14%)
Query: 208 SSNPCLQCTCLRSRVRCMALKCPPSPCPEPVLRPGHCCPT-CQG--CTEGGSHWEHGQEW 264
SS CL +C CP S C P P C P C CT
Sbjct: 11 SSRVCLPGSCDSCSDSWQVDDCPESCCEPPCCAPSCCAPAPCLSLVCTPVSRVSSPCCPV 70
Query: 265 TTPGDPCRI-CRCLEGHIQCRQRECASLCPYPARPLPGTCCPVCDGCFLNGREHRSGEPV 323
T PC+ C C+Q C C + C PVC C + PV
Sbjct: 71 TCEPSPCQSGCTSSCTPSCCQQSSCQLACCASSPCQQACCVPVC--CKTVCCKPVCCVPV 128
Query: 324 GSGDPCSHCRCANGSVQCEPLPCPPVPCRHPGKIPGQCCPVCDGCEYQGHQYQSQETFRL 383
GD S C C S C+ C PC+ +P C PVC G Q S +
Sbjct: 129 CCGD--SSC-CQQSS--CQSACCTSSPCQQACCVPICCKPVCSGISSSCCQQSSCVSCVS 183
Query: 384 QE--RGLCVRCSCQAGEVS------CEEQECPVTPCALPASGRQLC--PACELDGEEFAE 433
+ +C CQ+G +S C++ C C +S +Q C P C +
Sbjct: 184 SPCCQAVCEPSPCQSGCISSCTPSCCQQSSCQ-PACCTSSSCQQACCVPVC-------CK 235
Query: 434 GVQWEPDGRPCTACVCQDGVPKCGAVLCPPAPCQHPTQPPGACCPSCDSCTYHSQVYANG 493
V +P ++ CQ C C +PCQ P C P C + +
Sbjct: 236 TVCCKPVCSEDSSSCCQQS--SCQPACCTSSPCQQACCVPVCCKPVC------CKPVGSV 287
Query: 494 QNFTDADSPCHACHCQDGTVTCSLVDCPPTTCARPQSGPGQCCPRCPDCILEEEVFVDGE 553
+ A S C C C P C QS G C P C + V
Sbjct: 288 PICSGASSLC-----------CQQSSCQPACCTSSQSQQGCCVPVCCKPVSCVPVCSGAS 336
Query: 554 SFSHPRDPCQECRCQEGHAHCQP--------RPCPRAPCAHPLPGTCCP 594
S + CQ C + C+P RP R C P+P C P
Sbjct: 337 SSCCQQSSCQPACCTT--SCCRPSSSVSLLCRPVCRPACCVPVPSCCAP 383
Score = 75.1 bits (183), Expect = 2e-13
Identities = 104/427 (24%), Positives = 135/427 (31%), Gaps = 86/427 (20%)
Query: 388 LCVRCSCQAGEVSCEEQECPVTPCALPASGRQLCPACELDGEEFAEGVQWEPDGRPCTAC 447
+C+ SC + S + +CP + C P C PC +
Sbjct: 14 VCLPGSCDSCSDSWQVDDCPESCCEPPCCAPSCCAPA------------------PCLSL 55
Query: 448 VCQDGV---PKCGAVLCPPAPCQHPTQPPGACCPSCDSCTYHSQVYANGQNFTDADSPCH 504
VC C V C P+PCQ +C PSC C S A A SPC
Sbjct: 56 VCTPVSRVSSPCCPVTCEPSPCQSGCT--SSCTPSC--CQQSSCQLA-----CCASSPCQ 106
Query: 505 ACHCQDGTVTCSLVDCPPTTCARPQSGPGQCCPRCPDCILEEEVFVDGESFSHPRDPCQE 564
C V C V C P C G CC + C +S PCQ+
Sbjct: 107 QACCVP--VCCKTVCCKPVCCVPVCCGDSSCCQQS-SC----------QSACCTSSPCQQ 153
Query: 565 CRCQEGHAHCQP-------RPCPRAPCAHPLPGTCC-----PNDC-SGCAFGGKEYPSGA 611
C C+P C ++ C + CC P+ C SGC PS
Sbjct: 154 ACCVP--ICCKPVCSGISSSCCQQSSCVSCVSSPCCQAVCEPSPCQSGCISSCT--PSCC 209
Query: 612 DFPHPSDPCRLCRCLSGNVQ--CLARRCVPLPCPEPVLLP--GECCPQCPAAPA---PAG 664
C+ C S + Q C C C +PV CC Q PA +
Sbjct: 210 Q----QSSCQPACCTSSSCQQACCVPVCCKTVCCKPVCSEDSSSCCQQSSCQPACCTSSP 265
Query: 665 CPRPGAAHARHQEYFSPPGDPCRRCLCLDGSVSCQRLPCPPAPC--AHPRQGPCCPSCD- 721
C + + P C S+ CQ+ C PA C + +QG C P C
Sbjct: 266 CQQACCVPVCCKPVCCKPVGSVPICSGAS-SLCCQQSSCQPACCTSSQSQQGCCVPVCCK 324
Query: 722 --GCL--YQGKEFASGERFPSPTAACHLCLCW-EGSVS------CEPKACAPALCPFPAR 770
C+ G + ++ A C C SVS C P C P
Sbjct: 325 PVSCVPVCSGASSSCCQQSSCQPACCTTSCCRPSSSVSLLCRPVCRPACCVPVPSCCAPT 384
Query: 771 GDCCPDC 777
C P C
Sbjct: 385 SSCQPSC 391
Score = 73.6 bits (179), Expect = 7e-13
Identities = 100/400 (25%), Positives = 132/400 (33%), Gaps = 75/400 (18%)
Query: 110 EPDACTACVCQDG---AAHCGPQAHL--PHCR-GCSQNGQTYGNGETFSPDACTTCRCLE 163
EP C C + C P + + P C C + G + +P C C
Sbjct: 38 EPPCCAPSCCAPAPCLSLVCTPVSRVSSPCCPVTCEPSPCQSGCTSSCTPSCCQQSSCQ- 96
Query: 164 GTITCNQKPCPRGPCPEPGACCPH--CKPGCDYEGQLYEEGVTFLSSSNPCLQCTCLRSR 221
C PC + C CC CKP C V + C Q +
Sbjct: 97 -LACCASSPCQQACCVP--VCCKTVCCKPVCC---------VPVCCGDSSCCQ------Q 138
Query: 222 VRCMALKCPPSPCPEPVLRPGHCCPTCQGCTEGGSHWEHGQEWTTPGDPC--RICR---C 276
C + C SPC + P C P C G + S + + PC +C C
Sbjct: 139 SSCQSACCTSSPCQQACCVPICCKPVCSGIS--SSCCQQSSCVSCVSSPCCQAVCEPSPC 196
Query: 277 LEGHIQ------CRQRECASLCPYPARPLPGTCCPVCDGCFLNGREHRSGEPVGSGDPCS 330
G I C+Q C C + C PVC C + +PV S D S
Sbjct: 197 QSGCISSCTPSCCQQSSCQPACCTSSSCQQACCVPVC--C-----KTVCCKPVCSEDSSS 249
Query: 331 HCRCANGSVQCEPLPCPPVPCRHPGKIPGQCCPVCDGCEYQGHQYQSQETFRLQERGLCV 390
C+ ++ C+P C PC+ +P C PVC C+ G L C
Sbjct: 250 CCQQSS----CQPACCTSSPCQQACCVPVCCKPVC--CKPVGSVPICSGASSL----CCQ 299
Query: 391 RCSCQAG--EVSCEEQECPVTPCALPASGRQLCPACELDGEEFAEGVQWEPDGRPCTACV 448
+ SCQ S +Q C V C P S P C + +P CT
Sbjct: 300 QSSCQPACCTSSQSQQGCCVPVCCKPVS---CVPVCSGASSSCCQQSSCQP--ACCTTSC 354
Query: 449 CQDGV-------PKCGAVLCPPAP-CQHPTQPPGACCPSC 480
C+ P C C P P C PT +C PSC
Sbjct: 355 CRPSSSVSLLCRPVCRPACCVPVPSCCAPT---SSCQPSC 391
>gi|148727298 keratin associated protein 10-6 [Homo sapiens]
Length = 365
Score = 86.3 bits (212), Expect = 1e-16
Identities = 100/424 (23%), Positives = 130/424 (30%), Gaps = 134/424 (31%)
Query: 388 LCVRCSCQAGEVSCEEQECPVTPCALPASGRQLCPACELDGEEFAEGVQWEPDGRPCTAC 447
+C+ SC + S + +CP + C P PA PC +
Sbjct: 19 VCLPGSCDSCSDSWQVDDCPESCCEPPCCA----PA-------------------PCLSL 55
Query: 448 VCQDGV---PKCGAVLCPPAPCQHPTQPPGACCPSCDSCTYHSQVYANGQNFTDADSPCH 504
VC C V C P+PCQ +C PSC C S A A SPC
Sbjct: 56 VCTPVSRVSSPCCPVTCEPSPCQSGCT--SSCTPSC--CQQSSCQLA-----CCASSPCQ 106
Query: 505 ACHCQDGTVTCSLVDCPPTTCARPQSGPGQCCPRCPDCILEEEVFVDGESFSHPRDPCQE 564
C V C V C P C G CC Q+
Sbjct: 107 QACCVP--VCCKTVCCKPVCCVSVCCGDSSCC--------------------------QQ 138
Query: 565 CRCQEGHAHCQPRPCPRAPCAHPLPGTCCPNDCSGCAFGGKEYPSGADFPHPSDPCRLCR 624
CQ A C PC +A C CC CSG + S C+
Sbjct: 139 SSCQS--ACCTSSPCQQACCVP----VCCKPVCSGIS---------------SSCCQQSS 177
Query: 625 CLSGNVQCLARRCVPLPCPEPVLLPGECCPQCPAAPAPAGCPRPGAAHARHQEYFSPPGD 684
C+S CV PC + V P C C ++ P+ C +
Sbjct: 178 CVS---------CVSSPCCQAVCEPSPCQSGCTSSCTPSCCQQSSCQPT------CCTSS 222
Query: 685 PCRRCLCL---------------DGSVSCQRLPCPPAPC-AHPRQGPCC-PSCDGCLYQG 727
PC++ C+ D S CQ+ C PA C + P Q CC P C G
Sbjct: 223 PCQQACCVPVCCVPVCCVPTCSEDSSSCCQQSSCQPACCTSSPCQHACCVPVCSG----- 277
Query: 728 KEFASGERFPSPTAACHLCLCWEGSVS---CEPKACAPALCPFPARGDCCPDCDGEGHGI 784
+ T+ C C + C P + LC + CC G
Sbjct: 278 ----------ASTSCCQQSSCQPACCTASCCRPSSSVSLLCHPVCKSTCCVPVPSCGASA 327
Query: 785 GSCR 788
SC+
Sbjct: 328 SSCQ 331
Score = 75.9 bits (185), Expect = 1e-13
Identities = 95/396 (23%), Positives = 129/396 (32%), Gaps = 97/396 (24%)
Query: 288 CASLCPYPARP-LPGTCCPVCDGCFLNGREHRSGEPVGSGDPCSHCRCANGSVQCEPLPC 346
C+S Y +R LPG+C D ++ EP PC C P PC
Sbjct: 9 CSSDLSYGSRVCLPGSCDSCSDSWQVDDCPESCCEP-----PC-----------CAPAPC 52
Query: 347 PPVPCRHPGKIPGQCCPV-CDGCEYQGHQYQSQETFRLQERGLCVRCSCQAGEVSCEEQE 405
+ C ++ CCPV C+ Q S C CQ + SC+
Sbjct: 53 LSLVCTPVSRVSSPCCPVTCEPSPCQSGCTSS-----------CTPSCCQ--QSSCQLAC 99
Query: 406 CPVTP----CALPASGRQLC--PACELDGEEFAEGVQWEPDGRPCTACVCQDG----VPK 455
C +P C +P + +C P C C + C D
Sbjct: 100 CASSPCQQACCVPVCCKTVCCKPVC-------------------CVSVCCGDSSCCQQSS 140
Query: 456 CGAVLCPPAPCQHPTQPPGACCPSC----DSCTYHSQVYANGQNFTDADSPCHACHCQDG 511
C + C +PCQ P C P C SC S + + + C CQ G
Sbjct: 141 CQSACCTSSPCQQACCVPVCCKPVCSGISSSCCQQSSC-VSCVSSPCCQAVCEPSPCQSG 199
Query: 512 TVT------CSLVDCPPTTCARPQSGPGQCCPRC--PDCILEEEVFVDGESFSHPRDPCQ 563
+ C C PT C C P C P C + + S C
Sbjct: 200 CTSSCTPSCCQQSSCQPTCCTSSPCQQACCVPVCCVPVCCV--------PTCSEDSSSC- 250
Query: 564 ECRCQEGHAHCQPRPCPRAPCAHPLPGTCCPNDCSGCAFGGKEYPSGADFPHPSDPCRLC 623
CQ+ + CQP C +PC H CC CSG + + S + CR
Sbjct: 251 ---CQQ--SSCQPACCTSSPCQH----ACCVPVCSGASTSCCQQSSCQPACCTASCCRPS 301
Query: 624 RCLS--GNVQCLARRCVPLP-CPEPVLLPGECCPQC 656
+S + C + CVP+P C C P C
Sbjct: 302 SSVSLLCHPVCKSTCCVPVPSCGASA---SSCQPSC 334
Score = 66.2 bits (160), Expect = 1e-10
Identities = 95/419 (22%), Positives = 124/419 (29%), Gaps = 123/419 (29%)
Query: 113 ACTACVCQDGAAHCGPQAHLP-HCRGCSQNGQTYGNGETF-SPDACTTCRCLEGTIT--- 167
A T VC ++ G + LP C CS + Q E+ P C CL T
Sbjct: 3 ASTMSVCSSDLSY-GSRVCLPGSCDSCSDSWQVDDCPESCCEPPCCAPAPCLSLVCTPVS 61
Query: 168 -----CNQKPCPRGPCPEPGACCPHCKPGCDYEGQLYEEGVTFLSSSNPCLQCTCLR--- 219
C C PC C C P C + +S+PC Q C+
Sbjct: 62 RVSSPCCPVTCEPSPCQS--GCTSSCTPSCCQQSSCQ----LACCASSPCQQACCVPVCC 115
Query: 220 ---------------------SRVRCMALKCPPSPCPEPVLRPGHCCPTCQGCTEGGSHW 258
+ C + C SPC + P C P C G + S
Sbjct: 116 KTVCCKPVCCVSVCCGDSSCCQQSSCQSACCTSSPCQQACCVPVCCKPVCSGIS--SSCC 173
Query: 259 EHGQEWTTPGDPCRICRCLEGHIQ-----------CRQRECASLCPYPARPLPGTCCPVC 307
+ + PC C Q C+Q C C + C PVC
Sbjct: 174 QQSSCVSCVSSPCCQAVCEPSPCQSGCTSSCTPSCCQQSSCQPTCCTSSPCQQACCVPVC 233
Query: 308 --DGCFLNGREHRSGEPVGSGDPCSHCRCANGSVQCEPLPCPPVPCRHPGKIPGQCCPVC 365
C + P S D S C+ ++ C+P C PC+H C PVC
Sbjct: 234 CVPVCCV---------PTCSEDSSSCCQQSS----CQPACCTSSPCQH-----ACCVPVC 275
Query: 366 DGCEYQGHQYQSQETFRLQERGLCVRCSCQAGEVSCEEQECPVTPCALPASGRQLC--PA 423
G C + SCQ C C P+S L P
Sbjct: 276 SGA----------------STSCCQQSSCQPA--------CCTASCCRPSSSVSLLCHPV 311
Query: 424 CELDGEEFAEGVQWEPDGRPCTACVCQDGVPKCGAVL--CPPAPCQHPTQPPGACCPSC 480
C+ T CV VP CGA C P+ C+ + C P C
Sbjct: 312 CK------------------STCCV---PVPSCGASASSCQPSCCRTASCVSLLCRPMC 349
>gi|55770876 notch4 preproprotein [Homo sapiens]
Length = 2003
Score = 85.1 bits (209), Expect = 2e-16
Identities = 185/777 (23%), Positives = 238/777 (30%), Gaps = 190/777 (24%)
Query: 117 CVCQDGAAHCGPQAHLPHCRG--CSQNGQTYGNGETFSPDACTTCRCLEG---------T 165
C+C G + + + CR C+ GQ F C+CL G
Sbjct: 537 CICLPGFSGTRCEEDIDECRSSPCANGGQCQDQPGAFH------CKCLPGFEGPRCQTEV 590
Query: 166 ITCNQKPCPRGP-CPE-PGACCPHCKPGCDYEGQLYEEGVTFLSSSNPCLQCTCLRSRVR 223
C PCP G C + PGA C G + GQL E + + P C + +
Sbjct: 591 DECLSDPCPVGASCLDLPGAFFCLCPSG--FTGQLCEVPLCAPNLCQPKQICKDQKDKAN 648
Query: 224 CMALKCPPSPCPEPVLRPGHCCPTCQGCTEGGSHWEHGQ-----EWTTPGDPCRICRCLE 278
C+ CP+ PG C P CT H + WT P + C+
Sbjct: 649 CL--------CPDG--SPG-CAPPEDNCTCHHGHCQRSSCVCDVGWTGPECEAELGGCIS 697
Query: 279 GHIQ----CRQRECASLCPYPARPLPGTCCPVCDGCF----LNGREHRSGEPVGSGDPCS 330
C + C P TC C LNG S P G C+
Sbjct: 698 APCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGG---SCNPSPGGYYCT 754
Query: 331 HCRCANGSVQCEPLP--CPPVPC-------RHPGKIPGQCCPVCDGCEYQGHQYQSQETF 381
C ++ QC+ C PC PG C G +G S
Sbjct: 755 -CPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADS 813
Query: 382 RLQERGLCV------RCSCQAGEVS---------CEEQECPVTPCALPASGRQLC----- 421
+ R C RC C G C ++ CP L C
Sbjct: 814 PCRNRATCQDSPQGPRCLCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQG 873
Query: 422 ---PACEL-----DGEEFAEGVQWEP---------DGRPCTACVCQDGVPKCGAVL---- 460
P C L ++G+ D P C C G G++
Sbjct: 874 WTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQ--GSLCQDHV 931
Query: 461 --CPPAPCQHPT----QPPGACCPSCDSCTYHSQVYANGQNFTDADSPCHACHCQD-GTV 513
C PCQ+ QP G C +GQN + C + C + GT
Sbjct: 932 NPCESRPCQNGATCMAQPSGYLCQCAPGY--------DGQNCSKELDACQSQPCHNHGT- 982
Query: 514 TCSLVDCPPTT----CARPQSGPGQCCPRCPDCILEEEVFVDGESFSHPRDPCQECRCQE 569
C P CA P G C D L++ G + H C+C
Sbjct: 983 ------CTPKPGGFHCACPPGFVGLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLP 1036
Query: 570 GHAH--CQPR--PCPRAPCAHPLPGTCCPNDCSGCAFGGKEYPSGADFP---HPSDPCRL 622
GH C+ PC PC H GTC S F P G + P H + C
Sbjct: 1037 GHTGQWCEVEIDPCHSQPCFHG--GTCEATAGSPLGFIC-HCPKGFEGPTCSHRAPSCGF 1093
Query: 623 CRCLSGNVQCLARRCVPLPCP----EPVLLPGECCPQCPAAPAPAGC--PRPGAAHARHQ 676
C G + C+P P P L G P C PAP GC P P +
Sbjct: 1094 HHCHHGGL------CLPSPKPGFPPRCACLSGYGGPDCLTPPAPKGCGPPSPCLYNGSCS 1147
Query: 677 EYFSPPGDPCRRCLCLDGSVS--CQRLPCPPAPCAHPRQGPCCPSCD-GCLYQGKEFASG 733
E + G P RC C S CQ+ P A R G +CD GC G + G
Sbjct: 1148 E-TTGLGGPGFRCSCPHSSPGPRCQK---PGAKGCEGRSGD--GACDAGCSGPGGNWDGG 1201
Query: 734 E---RFPSPTAACHLCLCWEGSVSCEPKACAPALCPFPAR-------GDCCPDCDGE 780
+ P P W+G CP +R G C P CD E
Sbjct: 1202 DCSLGVPDP---------WKG-------------CPSHSRCWLLFRDGQCHPQCDSE 1236
Score = 81.6 bits (200), Expect = 3e-15
Identities = 188/764 (24%), Positives = 227/764 (29%), Gaps = 222/764 (29%)
Query: 117 CVCQDGAAHCGP-----QAHLPHCRGCSQNGQTYGNGETFSPDACTTCRCLEGTI--TCN 169
C+C DG+ C P H HC+ S C C G C
Sbjct: 649 CLCPDGSPGCAPPEDNCTCHHGHCQRSS-------------------CVCDVGWTGPECE 689
Query: 170 QK--PCPRGPCPEPGACCP-----HCKPGCDYEGQLYEEGVTFLSSSNPCLQCTCLRSRV 222
+ C PC G C P +C Y G E +T S PCL
Sbjct: 690 AELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMT-ACHSGPCLN-------- 740
Query: 223 RCMALKCPPSP------CPEPVLRPGHCCPTCQGCTEGGSHWEHGQEWTTPGDPCRICRC 276
C PSP CP P H P CQ T D C C
Sbjct: 741 ---GGSCNPSPGGYYCTCP-----PSHTGPQCQ----------------TSTDYCVSAPC 776
Query: 277 LEGHIQCRQRECASLCPYPARPLPGTCCPVCDGCFLNGREHRSGEPVGSGDPCSHCRCAN 336
G C R PGT +C F R P + PC +
Sbjct: 777 FNGG-TCVNR-------------PGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQ 822
Query: 337 GSVQCEPLPCPPVPCRHPGKIPGQCCPVCDGCEYQGHQYQSQETFRLQERGLCVRCSCQA 396
S Q CP G G C + D C Q + G C C
Sbjct: 823 DSPQGPRCLCP------TGYTGGSCQTLMDLCA----QKPCPRNSHCLQTGPSFHCLCLQ 872
Query: 397 GEVSCEEQECPVTPCALPASGRQLCPACE-LDGEEFAEGVQWEPDGRPCTACVCQDGVPK 455
G P+ C LP S Q + +D D P C C G
Sbjct: 873 GWTG------PL--CNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQ- 923
Query: 456 CGAVL------CPPAPCQH----PTQPPGACCPSCDSCTYHSQVYANGQNFTDADSPCHA 505
G++ C PCQ+ QP G C +GQN + C +
Sbjct: 924 -GSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPG--------YDGQNCSKELDACQS 974
Query: 506 CHCQD-GTVTCSLVDCPPTT----CARPQSGPGQCCPRCPDCILEEEVFVDGESFSHPRD 560
C + GT C P CA P G C D L++ G + H
Sbjct: 975 QPCHNHGT-------CTPKPGGFHCACPPGFVGLRCEGDVDECLDQPCHPTGTAACHSLA 1027
Query: 561 PCQECRCQEGH----AHCQPRPCPRAPCAHPLPGTC-------------CPNDCSG---- 599
C+C GH + PC PC H GTC CP G
Sbjct: 1028 NAFYCQCLPGHTGQWCEVEIDPCHSQPCFH--GGTCEATAGSPLGFICHCPKGFEGPTCS 1085
Query: 600 ----------CAFGGKEYPSGADFPHPSDPCRLCRCLS--GNVQCLA----RRCVPLPCP 643
C GG PS P P P R C CLS G CL + C P P
Sbjct: 1086 HRAPSCGFHHCHHGGLCLPS----PKPGFPPR-CACLSGYGGPDCLTPPAPKGCGP---P 1137
Query: 644 EPVLLPGECCP-----------QCPAAPAPAGCPRPGAAHARHQEYFSPPGDPCRRCLC- 691
P L G C CP + C +PGA + GD C
Sbjct: 1138 SPCLYNGSCSETTGLGGPGFRCSCPHSSPGPRCQKPGAKGCEGRS-----GDGACDAGCS 1192
Query: 692 -----LDGSVSCQRLPCPPAPC-AHP------RQGPCCPSCDG--CLYQGKEFASGERFP 737
DG +P P C +H R G C P CD CL+ G + E P
Sbjct: 1193 GPGGNWDGGDCSLGVPDPWKGCPSHSRCWLLFRDGQCHPQCDSEECLFDGYDC---ETPP 1249
Query: 738 SPTAAC-HLCLCWEGSVSCEPKACAPALCPFPARGDCCPDCDGE 780
+ T A C + CE K C A C + GDC P+ DG+
Sbjct: 1250 ACTPAYDQYCHDHFHNGHCE-KGCNTAECGWDG-GDCRPE-DGD 1290
Score = 63.5 bits (153), Expect = 7e-10
Identities = 163/696 (23%), Positives = 209/696 (30%), Gaps = 189/696 (27%)
Query: 159 CRCLEGTI--TCNQKP-CPRGPCPEPGACCP-------HCKPGCDYEGQLYEEGVT-FLS 207
C C+ G C + C PC G C HC PG +EG E V
Sbjct: 143 CSCMPGWTGEQCQLRDFCSANPCVNGGVCLATYPQIQCHCPPG--FEGHACERDVNECFQ 200
Query: 208 SSNPCLQCTCLRSRVRCMALKCPPSP-CPEPVLRPGHCCPTCQGCTEGGSHWEHGQEWTT 266
PC + T + + CP P LR G C P +GC+ GG+ ++ +T
Sbjct: 201 DPGPCPKGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPP--RGCSNGGTCQLMPEKDST 258
Query: 267 PGDPCRICRCLEGHI---------QCRQRECAS-----------LCPYPARPLPGTCCPV 306
+C C G I C +C + C P C
Sbjct: 259 ----FHLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSED 314
Query: 307 CDGCFLNGREH-RSGEPVGSGDPCSHCRCANG--SVQCEPL--PCPPVPCRHPGKIPGQC 361
D C G H R+G + HC C +G CE C C PG
Sbjct: 315 VDECETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCA-----PGST 369
Query: 362 CPVCDGCEYQGHQYQSQETFRLQERGLCVRCSCQAGEVS--CE-EQECPVTPC------- 411
C +R C C G C E C PC
Sbjct: 370 CI---------------------DRVGSFSCLCPPGRTGLLCHLEDMCLSQPCHGDAQCS 408
Query: 412 ALPASGRQLC--------PACELDGEEFAEGVQWEPDGRPCTACVCQDGVPKCGAVLCPP 463
P +G LC P C D +E Q +C+ G C LCPP
Sbjct: 409 TNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNC---LCPP 465
Query: 464 A-----------PCQHPTQPPGACCPSCDSCTYHSQVYAN--GQNFTDADSPCHACHCQD 510
C PG+ C T+H GQ + C + C +
Sbjct: 466 GYTGSRCEADHNECLSQPCHPGSTCLDL-LATFHCLCPPGLEGQLCEVETNECASAPCLN 524
Query: 511 GTVTCSLVDCPPTTCARPQSGPGQCCPRCPDCILEEEVFVDGESFSHPRDPCQECRCQEG 570
L++ C PG RC EE++ E S P +C+ Q G
Sbjct: 525 HADCHDLLNGFQCICL-----PGFSGTRC-----EEDI---DECRSSPCANGGQCQDQPG 571
Query: 571 HAHCQ-------PR-----------PCPRAPCAHPLPGT---CCPNDCSG--CAFGGKEY 607
HC+ PR PCP LPG CP+ +G C E
Sbjct: 572 AFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLC-----EV 626
Query: 608 PSGADFPHPSDPCRLCRCLSGNVQCLARRCVPLPCPEPVLLPGECCPQCPAAPAPAGCPR 667
P A P+ P ++C+ CL CP+ P C AP C
Sbjct: 627 PLCA--PNLCQPKQICKDQKDKANCL--------CPDG-------SPGC--APPEDNC-- 665
Query: 668 PGAAHARHQEYFSPPGDPCRR--CLCLDG----SVSCQRLPCPPAPCAHPRQGPCCPSCD 721
H H C+R C+C G + C APCAH G C P
Sbjct: 666 --TCHHGH----------CQRSSCVCDVGWTGPECEAELGGCISAPCAH--GGTCYPQPS 711
Query: 722 GCLYQGKEFASGERFPSPTAACHLCLCWEGSVSCEP 757
G +G ACH C G SC P
Sbjct: 712 GYNCTCPTGYTGPTCSEEMTACHSGPCLNGG-SCNP 746
Score = 60.5 bits (145), Expect = 6e-09
Identities = 158/658 (24%), Positives = 202/658 (30%), Gaps = 152/658 (23%)
Query: 207 SSSNPCLQC-TCLRSRVRCMALKCPPSPCPEPVLRPGHCCPTCQGCTEGGSHWE------ 259
S PC TCL + +C P E P C Q C GGS
Sbjct: 30 SFPEPCANGGTCLSLSLGQGTCQCAPGFLGETCQFPDPC-QNAQLCQNGGSCQALLPAPL 88
Query: 260 HGQEWTTPGDPCRICRCLEGHIQCRQRECASLCPYPARPLPGTCCPVCDGCFL--NGREH 317
+P P +C CL G +R A L P P + C C + +GR
Sbjct: 89 GLPSSPSPLTPSFLCTCLPGFTG--ERCQAKL----EDPCPPSFCSKRGRCHIQASGRPQ 142
Query: 318 RSGEPVGSG------DPCSHCRCANGSVQCEPLPCPPVPCRHPGKIPGQCCPVCDGCEYQ 371
S P +G D CS C NG V P + C P PG ++
Sbjct: 143 CSCMPGWTGEQCQLRDFCSANPCVNGGVCLATYP--QIQCHCP---PG----------FE 187
Query: 372 GHQYQSQETFRLQERGLCVR------------CSCQAGEVS--CEEQECPVTPCALPASG 417
GH + Q+ G C + C C G+ CE + P P G
Sbjct: 188 GHACERDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGG 247
Query: 418 R-QLCPA-------CELDGEEFAEGVQWEPDGRPCTAC----VCQDGVPKCGAVLCPPAP 465
QL P C + PD C CQDG+ LCP
Sbjct: 248 TCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTY-TCLCPE-- 304
Query: 466 CQHPTQPPGACCPSCDSCTYHSQVYANGQNFTDADSPCHACHCQDGT--VTC--SLVDCP 521
T C D C + + C C G +C +L DC
Sbjct: 305 ----TWTGWDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCI 360
Query: 522 PTTCARPQS-----GPGQC-CP--------RCPDCILEEEVFVDGESFSHPRDPCQECRC 567
TCA + G C CP D L + D + ++P C C
Sbjct: 361 AATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLC 420
Query: 568 QEGHAHCQPRPCPRAPCAHPLPGTC--CPNDCSGCAFGGKEYPSGADFPHPSDPCRL-CR 624
Q G++ P H C S C GG + F P R
Sbjct: 421 QPGYS---------GPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSR 471
Query: 625 CLSGNVQCLARRCVP----------LPCPEPVLLPGECCP----QCPAAPA--PAGCPR- 667
C + + +CL++ C P C P L G+ C +C +AP A C
Sbjct: 472 CEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNECASAPCLNHADCHDL 531
Query: 668 ---------PGAAHARHQEYFSPPGDPCRRCLCLDGSVSCQRLPCP-PAPCAHPRQGPCC 717
PG + R +E D CR C +G CQ P C +GP C
Sbjct: 532 LNGFQCICLPGFSGTRCEEDI----DECRSSPCANGG-QCQDQPGAFHCKCLPGFEGPRC 586
Query: 718 PS-CDGCLYQGKEFASGERFPSPTAACHL-------CLCWEGSVS--CEPKACAPALC 765
+ D CL P P A L CLC G CE CAP LC
Sbjct: 587 QTEVDECLSD----------PCPVGASCLDLPGAFFCLCPSGFTGQLCEVPLCAPNLC 634
>gi|38348414 von Willebrand factor C domain containing 2 [Homo
sapiens]
Length = 325
Score = 84.7 bits (208), Expect = 3e-16
Identities = 58/178 (32%), Positives = 77/178 (43%), Gaps = 27/178 (15%)
Query: 136 RGC-SQNGQTYGNGETFSP--DACTTCRCLEGTITCNQKPCPR--GPC--PEPGACCPHC 188
+GC ++G Y GE F+P AC C C E C Q CPR C + CCP C
Sbjct: 153 KGCVDESGFVYAIGEKFAPGPSACP-CLCTEEGPLCAQPECPRLHPRCIHVDTSQCCPQC 211
Query: 189 KPG---CDYEGQLYEEGVTFLSSSNPCLQCTC-LRSRVRCMALKCPPSPCPEPVLRPGHC 244
K C++ G+ Y+ F+ S PC +C C V C CP + C +PV P C
Sbjct: 212 KERKNYCEFRGKTYQTLEEFVVS--PCERCRCEANGEVLCTVSACPQTECVDPVYEPDQC 269
Query: 245 CPTCQ---GCTEGGSHWEHGQEWTTPGDPCRICRC--------LEGHIQCRQRECASL 291
CP C+ C + G+E T D C IC C +E C + EC +
Sbjct: 270 CPICKNGPNCFAETAVIPAGREVKT--DECTICHCTYEEGTWRIERQAMCTRHECRQM 325
Score = 77.4 bits (189), Expect = 5e-14
Identities = 53/168 (31%), Positives = 68/168 (40%), Gaps = 22/168 (13%)
Query: 428 GEEFAEGVQWEPDGRPCTACVCQDGVPKCGAVLCPPAPCQHPTQPPGACCPSCDS----C 483
GE+FA G P PC +C + P C CP + CCP C C
Sbjct: 166 GEKFAPG----PSACPC---LCTEEGPLCAQPECPRLHPRCIHVDTSQCCPQCKERKNYC 218
Query: 484 TYHSQVYANGQNFTDADSPCHACHCQ-DGTVTCSLVDCPPTTCARPQSGPGQCCPRC--- 539
+ + Y + F SPC C C+ +G V C++ CP T C P P QCCP C
Sbjct: 219 EFRGKTYQTLEEFVV--SPCERCRCEANGEVLCTVSACPQTECVDPVYEPDQCCPICKNG 276
Query: 540 PDCILEEEVFVDGESFSHPRDPCQECRC--QEGHAHCQPRP-CPRAPC 584
P+C E V G D C C C +EG + + C R C
Sbjct: 277 PNCFAETAVIPAGREVK--TDECTICHCTYEEGTWRIERQAMCTRHEC 322
Score = 72.8 bits (177), Expect = 1e-12
Identities = 55/191 (28%), Positives = 76/191 (39%), Gaps = 30/191 (15%)
Query: 232 SPCPEPVLRPGHCCPTCQGCT-EGGSHWEHGQEWTTPGDPCRICRCLEGHIQCRQRECAS 290
+P PEP + +GC E G + G+++ PG C C E C Q EC
Sbjct: 136 APTPEPPEEYVYPDYRGKGCVDESGFVYAIGEKFA-PGPSACPCLCTEEGPLCAQPECPR 194
Query: 291 LCPYPARPLPGTCCPVC----DGCFLNGREHRSGEPVGSGDPCSHCRC-ANGSVQCEPLP 345
L P CCP C + C G+ +++ E PC CRC ANG V C
Sbjct: 195 LHPRCIHVDTSQCCPQCKERKNYCEFRGKTYQTLEEFVVS-PCERCRCEANGEVLCTVSA 253
Query: 346 CPPVPCRHPGKIPGQCCPVC---------------------DGCEYQGHQYQSQETFRLQ 384
CP C P P QCCP+C D C Y+ + T+R++
Sbjct: 254 CPQTECVDPVYEPDQCCPICKNGPNCFAETAVIPAGREVKTDECTICHCTYE-EGTWRIE 312
Query: 385 ERGLCVRCSCQ 395
+ +C R C+
Sbjct: 313 RQAMCTRHECR 323
Score = 68.9 bits (167), Expect = 2e-11
Identities = 50/148 (33%), Positives = 60/148 (40%), Gaps = 15/148 (10%)
Query: 313 NGREHRSGEPVGSGDPCSHCRCANGSVQCEPLPCPPVPCRHPGKIPGQCCPVC----DGC 368
+G + GE G C C C CP + R QCCP C + C
Sbjct: 159 SGFVYAIGEKFAPGPSACPCLCTEEGPLCAQPECPRLHPRCIHVDTSQCCPQCKERKNYC 218
Query: 369 EYQGHQYQSQETFRLQERGLCVRCSCQA-GEVSCEEQECPVTPCALPA-SGRQLCPACEL 426
E++G YQ+ E F + C RC C+A GEV C CP T C P Q CP C+
Sbjct: 219 EFRGKTYQTLEEFVVSP---CERCRCEANGEVLCTVSACPQTECVDPVYEPDQCCPICKN 275
Query: 427 DGEEFAEGVQWEPDGR-----PCTACVC 449
FAE P GR CT C C
Sbjct: 276 GPNCFAE-TAVIPAGREVKTDECTICHC 302
Score = 67.0 bits (162), Expect = 7e-11
Identities = 42/120 (35%), Positives = 49/120 (40%), Gaps = 11/120 (9%)
Query: 548 VFVDGESFSHPRDPCQECRCQEGHAHCQPRPCPRAP--CAHPLPGTCCPNDCSG----CA 601
V+ GE F+ C C C E C CPR C H CCP C C
Sbjct: 162 VYAIGEKFAPGPSACP-CLCTEEGPLCAQPECPRLHPRCIHVDTSQCCPQ-CKERKNYCE 219
Query: 602 FGGKEYPSGADFPHPSDPCRLCRC-LSGNVQCLARRCVPLPCPEPVLLPGECCPQCPAAP 660
F GK Y + +F PC CRC +G V C C C +PV P +CCP C P
Sbjct: 220 FRGKTYQTLEEFV--VSPCERCRCEANGEVLCTVSACPQTECVDPVYEPDQCCPICKNGP 277
Score = 52.8 bits (125), Expect = 1e-06
Identities = 35/110 (31%), Positives = 44/110 (40%), Gaps = 12/110 (10%)
Query: 677 EYFSPPGDPCRRCLCLDGSVSCQRLPCP--PAPCAHPRQGPCCPSC----DGCLYQGKEF 730
E F+P C CLC + C + CP C H CCP C + C ++GK +
Sbjct: 167 EKFAPGPSAC-PCLCTEEGPLCAQPECPRLHPRCIHVDTSQCCPQCKERKNYCEFRGKTY 225
Query: 731 ASGERFPSPTAACHLCLC-WEGSVSCEPKACAPALC--PFPARGDCCPDC 777
+ E F + C C C G V C AC C P CCP C
Sbjct: 226 QTLEEF--VVSPCERCRCEANGEVLCTVSACPQTECVDPVYEPDQCCPIC 273
Score = 34.3 bits (77), Expect = 0.48
Identities = 27/80 (33%), Positives = 32/80 (40%), Gaps = 11/80 (13%)
Query: 702 PCPPAPCAHPR-QGPCCPSCDGCLYQGKEFASGERFPSPTAACHLCLCWEGSVSCEPKAC 760
P PP +P +G C G +Y A GE+F +AC CLC E C C
Sbjct: 139 PEPPEEYVYPDYRGKGCVDESGFVY-----AIGEKFAPGPSACP-CLCTEEGPLCAQPEC 192
Query: 761 APAL---CPFPARGDCCPDC 777
P L C CCP C
Sbjct: 193 -PRLHPRCIHVDTSQCCPQC 211
>gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens]
Length = 1541
Score = 80.9 bits (198), Expect = 4e-15
Identities = 193/752 (25%), Positives = 229/752 (30%), Gaps = 166/752 (22%)
Query: 78 QTRVRQLESCECHPASPQC--------WGLGRAWPEGARWEPDACTACVCQDGAAHCGPQ 129
QTR CHPA+ C + RA G W PD C C G C
Sbjct: 827 QTRCSCANDGHCHPATGHCSCAPGWTGFSCQRACDTG-HWGPDCSHPCNCSAGHGSCDAI 885
Query: 130 AHL---------PHCRGCSQNGQTYGNGETFSPDACTTCRCLEGTITCNQKPCPRGPCPE 180
+ L P C G F P C+C G + P
Sbjct: 886 SGLCLCEAGYVGPRCEQQCPQGH-------FGPGCEQRCQCQHGAACDHVSGACTCPAGW 938
Query: 181 PGACCPHCKPGCDYEGQLYEEGVTFLSSSNPCLQCTCLRSRVRCMALKCPPS----PCPE 236
G C H P + G+ S+ N C C+ CP C E
Sbjct: 939 RGTFCEHACPAGFF-------GLDCRSACNCTAGAACDAVNGSCL---CPAGRRGPRCAE 988
Query: 237 --PVLRPGHCCPTCQGCTEGGS-HWEHGQEWTTPGDPCRICRCLEGHIQCRQRECASLCP 293
P GH C C G S HGQ C C G + C CP
Sbjct: 989 TCPAHTYGHNCSQACACFNGASCDPVHGQ-----------CHCAPGWM---GPSCLQACP 1034
Query: 294 YPARPLPGTCCPVCDGCFLNGREHRSGEPVGSGDPCS-HCRCANG--SVQCEPLPCPP-- 348
L G C C NG G+ DP S HC C G + CE C P
Sbjct: 1035 ---AGLYGDNCRHSCLC-QNG---------GTCDPVSGHCACPEGWAGLACEK-ECLPRD 1080
Query: 349 --VPCRHPGKI--PGQCCPVCDGC----EYQGHQYQSQETFRLQERGLCVRCSCQAGEVS 400
CRH G G C P C + G + QS RCSC G +
Sbjct: 1081 VRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQRCSCPPG-AA 1139
Query: 401 CEE--QECPVTPCALPASGRQLCPACELDGEEFAEGVQWEPDGRPCTACVCQDGVPKCGA 458
C C P + Q CP GE+ A+ Q P P AC G C A
Sbjct: 1140 CHHVTGACRCPPGFTGSGCEQACPPGSF-GEDCAQMCQC-PGENP--ACHPATGTCSCAA 1195
Query: 459 VLCPPAPCQHPTQPPGACCPSCDSCTYHSQVYANGQNFTDADSPCHACHCQDGTVTCSLV 518
P+ CQ PPG P C+ N D+ AC C G +
Sbjct: 1196 GYHGPS-CQQRC-PPGRYGPGCEQ-------LCGCLNGGSCDAATGACRCPTGFLG---T 1243
Query: 519 DCPPTTCARPQSGPGQCCPRCPDCILEEEVFVDGESFSHPRDPCQ-ECRCQEGHAHCQPR 577
DC TC + + GP C C G DP C C G A +
Sbjct: 1244 DC-NLTCPQGRFGP-NCTHVC------------GCGQGAACDPVTGTCLCPPGRAGVR-- 1287
Query: 578 PCPRAPCAHPLPGTCCPNDCSGCAFGGKEYPSGADFPHPSDPCRLCRCLSGNVQC----L 633
C R C G C + CS C GG LC +G+ C
Sbjct: 1288 -CERG-CPQNRFGVGCEHTCS-CRNGG-----------------LCHASNGSCSCGLGWT 1327
Query: 634 ARRCVPLPCPEPVLLPGECCPQC------PAAPAPAGCPRPGAAHARHQEYFSPPGDPCR 687
R C L CP P C +C PA C + + E+ PPG
Sbjct: 1328 GRHC-ELACP-PGRYGAACHLECSCHNNSTCEPATGTCRCGPGFYGQACEHPCPPGFHGA 1385
Query: 688 RCLCLDGSVSCQRLPCPPAPCAHPRQGPC-CPSCDGCLYQGKEFASGERFPSPTAACHLC 746
C G CQ APC P G C CP+ + G G S CH
Sbjct: 1386 GC---QGLCWCQH----GAPC-DPISGRCLCPAG----FHGHFCERGCEPGSFGEGCHQR 1433
Query: 747 LCWEGSVSCEPKACAPALCPFPARGDCCP-DC 777
+G C+P LCP G C DC
Sbjct: 1434 CDCDGGAPCDP-VTGLCLCPPGRSGATCNLDC 1464
Score = 75.5 bits (184), Expect = 2e-13
Identities = 194/772 (25%), Positives = 240/772 (31%), Gaps = 211/772 (27%)
Query: 89 CHPASPQCWGLGRAWPEGARWEPDACTACVCQDGAAHCGPQAHLPHCRGCSQNGQTYGNG 148
CH P W G E + +C +DG+ C C+ + G
Sbjct: 637 CHLTCPP-WAFGPGCSEECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAECELGY----- 690
Query: 149 ETFSPDACTTCRCLEGTITCNQKPCPRGPCPEPGACCPHCKPG--CDYEGQLYEEGVTFL 206
F P C C G + C+ G C G CP G C E + GV
Sbjct: 691 --FGPGCWQACTCPVG-VACDSVS---GEC---GKRCPAGFQGEDCGQECPVGTFGVN-C 740
Query: 207 SSSNPCLQCTCLRSRVRCMALKCPPSPCPEPVLRPGHCCPTCQGCTEGGSHWEHGQEWTT 266
SSS C C +C +CPP R G C C EG W G +
Sbjct: 741 SSSCSCGGAPCHGVTGQC---RCPPG-------RTGEDCEA--DCPEG--RWGLGCQEIC 786
Query: 267 PG-------DP-CRICRCLEGHIQCRQRECASLCPYPARPLPGTCCPVCDGCFLNGREHR 318
P DP C CL G + R C +CP G C C +G H
Sbjct: 787 PACQHAARCDPETGACLCLPGFVGSR---CQDVCP---AGWYGPSCQTRCSCANDGHCHP 840
Query: 319 SGEPVGSGDPCSHCRCANGSVQCEPLPCPPVPCRHPGKIPGQCCPVCDGCEYQGHQYQSQ 378
+ HC CA PG C CD GH
Sbjct: 841 A---------TGHCSCA------------------PGWTGFSCQRACD----TGHWGPD- 868
Query: 379 ETFRLQERGLCVR-CSCQAGEVSCEEQECPVTPCALPASGRQLC------PACELDGEEF 431
C C+C AG SC+ SG LC P CE +
Sbjct: 869 ----------CSHPCNCSAGHGSCDA-----------ISGLCLCEAGYVGPRCEQQCPQG 907
Query: 432 AEGVQWEPDGRPCTACVCQDGVPKCGAVLCPPAPCQHPTQPPGAC-CPSCDSCTYHSQVY 490
G E C CQ G A C H + GAC CP+ T+
Sbjct: 908 HFGPGCEQ------RCQCQHG-----------AACDHVS---GACTCPAGWRGTFCEHAC 947
Query: 491 ANGQNFTDADSPCHACHCQDGTVTCSLVDCPPTTCARPQSGPGQCCPRCPDCILEEEVFV 550
G D S AC+C G C V+ C + GP +C CP
Sbjct: 948 PAGFFGLDCRS---ACNCTAGAA-CDAVN-GSCLCPAGRRGP-RCAETCP---------- 991
Query: 551 DGESFSHPRDPCQECRCQEGHAHCQPRPCPRAPCAHPLPGTCCPNDCSGCAFGGKEYPSG 610
+ ++ + Q C C G A C P + CA G C C +G
Sbjct: 992 ---AHTYGHNCSQACACFNG-ASCDPVH-GQCHCAPGWMGPSCLQACPAGLYG------- 1039
Query: 611 ADFPHPSDPCR-LCRCLSGNVQCLARRCVPLP----CPEP---VLLPGECCPQCPAAPA- 661
D CR C C +G C P+ CPE + EC P+ A
Sbjct: 1040 -------DNCRHSCLCQNGGT------CDPVSGHCACPEGWAGLACEKECLPRDVRAGCR 1086
Query: 662 -PAGCPRPGAAHARHQEYFSPPGDPCRRCL--CLDG---SVSCQRLPCPPAPCAHPRQGP 715
GC G P G +C CL G QR CPP H G
Sbjct: 1087 HSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQRCSCPPGAACHHVTGA 1146
Query: 716 C-CP---SCDGCLYQ------GKEFASGERFPSPTAACH----LCLCWEG--SVSCEPKA 759
C CP + GC G++ A + P ACH C C G SC+ +
Sbjct: 1147 CRCPPGFTGSGCEQACPPGSFGEDCAQMCQCPGENPACHPATGTCSCAAGYHGPSCQQR- 1205
Query: 760 CAPALCPFPARGDCCPDCDGEGHGIGSC---RGGMRETRG-LGQN-NLYCPR 806
CP G C G +G GSC G R G LG + NL CP+
Sbjct: 1206 -----CPPGRYGPGCEQLCGCLNG-GSCDAATGACRCPTGFLGTDCNLTCPQ 1251
Score = 41.2 bits (95), Expect = 0.004
Identities = 88/331 (26%), Positives = 119/331 (35%), Gaps = 71/331 (21%)
Query: 273 ICRCLEGHIQ------CRQREC-ASLCPYPARPLPGTCCPV-CDGCFLNGR-EHRSGEPV 323
+ RC G +Q C EC ASLC + R +PG+ P C F R ++ E
Sbjct: 107 VLRCCRGWMQQPDEEGCLSAECSASLCFHGGRCVPGSAQPCHCPPGFQGPRCQYDVDECR 166
Query: 324 GSGDPCSHCRCAN--GSVQCEPLP----------CPPVPCRHPGKIPGQCCPVCDGCEYQ 371
C H RC N GS CE P C + G G C C
Sbjct: 167 THNGGCQH-RCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGN--GGCQHHCVQLTIT 223
Query: 372 GHQYQSQETFRLQERGL-CVRCS-CQAGEVSCEEQECPVTPCALPASGRQLCPACELDGE 429
H+ Q + F+LQE G CVR S C SC + C V G C
Sbjct: 224 RHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMHR-CQVV------RGLARC-------- 268
Query: 430 EFAEGVQWEPDGRPCTACVCQDGVPKCGAVLCPPAPCQHP---TQPPGACCPSCDSCTYH 486
E G Q DG+ C + V +C A L A C H TQ C C
Sbjct: 269 ECHVGYQLAADGKAC------EDVDECAAGL---AQCAHGCLNTQGSFKCV-----CHAG 314
Query: 487 SQVYANGQNFTDADSPC-HACHCQDGTVTCSLVDCPPTTCARPQSGPGQCCPRCPDCILE 545
++ A+G+ + ++C +G CS C+ +GP CPR + +
Sbjct: 315 YELGADGRQCYRIEMEIVNSCEANNGG--CS------HGCSHTSAGPLCTCPRGYELDTD 366
Query: 546 EEVFVDGESFSHPRDPC--QECRCQEGHAHC 574
+ +D + + PC Q C G C
Sbjct: 367 QRTCIDVDDCAD--SPCCQQVCTNNPGGYEC 395
>gi|161019170 mucin 5AC [Homo sapiens]
Length = 6207
Score = 80.1 bits (196), Expect = 8e-15
Identities = 103/408 (25%), Positives = 137/408 (33%), Gaps = 112/408 (27%)
Query: 329 CSHCRCANGSVQCEPLPCPPVPCRHPGKIPGQCCPVCDGCEYQGHQYQSQETFRLQERGL 388
CS R A G + C+ L CPP P C P+ +Q E G+
Sbjct: 5681 CSDWRGATGGL-CD-LTCPPTKVYKP------CGPIQPATCNSRNQSPQLE-------GM 5725
Query: 389 CVRCSCQAGEVSCEEQECPVTPCALPASGRQLCPACELDGEEFAEGVQWEPDGRPCTACV 448
C C ++ + C Q CP DG G +W + C +CV
Sbjct: 5726 AEGCFCPEDQILFNAH---MGICV------QACPCVGPDGFPKFPGERWVSN---CQSCV 5773
Query: 449 CQDGVPKCGAVLCPPAPCQHPTQPPGACCPSCDSCTYHSQVYANGQNFTDADSPCHACHC 508
C +G +V C P PC QPP P + T A++PC C
Sbjct: 5774 CDEGSV---SVQCKPLPCDAQGQPPPCNRPGFVTVTRPR-----------AENPC----C 5815
Query: 509 QDGTVTCSLVDCPPTTCARPQSGPGQCCPRCPDCILEEEVFVDGESFSHPRDPCQECRCQ 568
+ C+ CP Q P CP P QE C
Sbjct: 5816 PETVCVCNTTTCP------------QSLPVCP--------------------PGQESICT 5843
Query: 569 EGHAHCQPRPCPRAPCAHPLPGTCCPNDCSGCAFGGKEYPSGADFPHPSDPCRLCRCLSG 628
+ C CP C L C++ G Y GA FP PC +C CLSG
Sbjct: 5844 QEEGDC----CPTFRCRPQL-----------CSYNGTFYGVGATFPGAL-PCHMCTCLSG 5887
Query: 629 N-----VQCLARRCVPLPCP---EPVLLPGECCPQCPAAPAPAGCPRP-GAAHARHQEYF 679
+ VQC C CP E + G+CC +C C P G ++ +
Sbjct: 5888 DTQDPTVQCQEDACNNTTCPQGFEYKRVAGQCCGEC----VQTACLTPDGQPVQLNETWV 5943
Query: 680 SPPGDPCRRCLC-LDGSV---SCQRLPCPPAPCAHP--RQGPCCPSCD 721
+ D C LC +G V + Q CP R+ CC SC+
Sbjct: 5944 NSHVDNCTVYLCEAEGGVHLLTPQPASCPDVSSCRGSLRKTGCCYSCE 5991
Score = 77.0 bits (188), Expect = 6e-14
Identities = 112/406 (27%), Positives = 143/406 (35%), Gaps = 74/406 (18%)
Query: 229 CPPSPCPEPVLRPGHCCPTCQGCTEGGSHWEHGQEWTTPGDPCR-----ICRCLEGHIQ- 282
CPP P + +L C G + D CR C+ LE + +
Sbjct: 5622 CPPQPLCDLML--SQVFAECHNLVPPGPFFN-----ACISDHCRGRLEVPCQSLEAYAEL 5674
Query: 283 CRQRECASLCPYPARPLPGTCCPVCDGCFLNGREHRSGEPVGSGDPCSHCRCANGSVQCE 342
CR R S G +CD L + +P G P + C N S Q E
Sbjct: 5675 CRARGVCS-------DWRGATGGLCD---LTCPPTKVYKPCGPIQPAT-CNSRNQSPQLE 5723
Query: 343 PLP----CPPVPC---RHPGKIPGQCCPVC--DGC-EYQGHQYQSQETFRLQERGLCVRC 392
+ CP H G I Q CP DG ++ G ++ S C C
Sbjct: 5724 GMAEGCFCPEDQILFNAHMG-ICVQACPCVGPDGFPKFPGERWVSN----------CQSC 5772
Query: 393 SCQAGEVSCEEQECPVTPCALPASGRQLCPACELDGEEFAEGVQWEPDGRPCTACVCQDG 452
C G VS + C PC A G+ P C G + E P T CVC
Sbjct: 5773 VCDEGSVSVQ---CKPLPC--DAQGQP--PPCNRPGFVTVTRPRAENPCCPETVCVCNTT 5825
Query: 453 VPKCGAVLCPPAPCQHPTQPPGACCPSC----DSCTYHSQVYANGQNFTDADSPCHACHC 508
+CPP TQ G CCP+ C+Y+ Y G F A PCH C C
Sbjct: 5826 TCPQSLPVCPPGQESICTQEEGDCCPTFRCRPQLCSYNGTFYGVGATFPGA-LPCHMCTC 5884
Query: 509 -----QDGTVTCSLVDCPPTTCARP---QSGPGQCCPRCPD--CILE--EEVFVDGESFS 556
QD TV C C TTC + + GQCC C C+ + V ++ +
Sbjct: 5885 LSGDTQDPTVQCQEDACNNTTCPQGFEYKRVAGQCCGECVQTACLTPDGQPVQLNETWVN 5944
Query: 557 HPRDPCQECRCQ-EGHAHC---QPRPCPR-APCAHPLPGTCCPNDC 597
D C C+ EG H QP CP + C L T C C
Sbjct: 5945 SHVDNCTVYLCEAEGGVHLLTPQPASCPDVSSCRGSLRKTGCCYSC 5990
Score = 70.1 bits (170), Expect = 8e-12
Identities = 98/381 (25%), Positives = 123/381 (32%), Gaps = 95/381 (24%)
Query: 437 WEPDGRPCTACVCQDGVPKCGAVLCPPAPCQH-PTQPPGACCPSCDSCTYHSQVYANGQN 495
W P G P TA P AP PT P P CD SQV+A N
Sbjct: 5598 WAPTGTPPTAS--------------PAAPVSSTPTPTPCPPQPLCDLML--SQVFAECHN 5641
Query: 496 FTDADSPCHAC---HCQDGT-VTCSLVDCPPTTCA--------RPQSGPGQCCPRCPDCI 543
+AC HC+ V C ++ C R +G G C CP
Sbjct: 5642 LVPPGPFFNACISDHCRGRLEVPCQSLEAYAELCRARGVCSDWRGATG-GLCDLTCPPTK 5700
Query: 544 LEEEVFVDGESFSHPRDPCQECRCQEGHAHCQPRP------CPRAPCAHPLPGTCCPNDC 597
+ + P P Q C + Q CP C C
Sbjct: 5701 VYK-----------PCGPIQPATCNSRNQSPQLEGMAEGCFCPEDQILFNAHMGICVQAC 5749
Query: 598 SGCAFGGKEYPSGADFPHPS--DPCRLCRCLSGNVQCLARRCVPLPCPEPVLLPGECCPQ 655
G +P FP C+ C C G+V +C PLPC
Sbjct: 5750 P--CVGPDGFPK---FPGERWVSNCQSCVCDEGSVSV---QCKPLPCD------------ 5789
Query: 656 CPAAPAPAGCPRPGAAHARHQEYFSPPGDPCRRCLCLDGSVSC-QRLP-CPPAP---CAH 710
A P C RPG +P C +C+ + +C Q LP CPP C
Sbjct: 5790 --AQGQPPPCNRPGFVTVTRPRAENPC---CPETVCVCNTTTCPQSLPVCPPGQESICTQ 5844
Query: 711 PRQGPCCPSC----DGCLYQGKEFASGERFPSPTAACHLCLCWEG-----SVSCEPKACA 761
+G CCP+ C Y G + G FP CH+C C G +V C+ AC
Sbjct: 5845 -EEGDCCPTFRCRPQLCSYNGTFYGVGATFPG-ALPCHMCTCLSGDTQDPTVQCQEDACN 5902
Query: 762 PALCP-----FPARGDCCPDC 777
CP G CC +C
Sbjct: 5903 NTTCPQGFEYKRVAGQCCGEC 5923
Score = 67.8 bits (164), Expect = 4e-11
Identities = 81/293 (27%), Positives = 110/293 (37%), Gaps = 64/293 (21%)
Query: 156 CTTCRCLEGTITCNQKPCPRGPCPEPGACCPHCKPGCDYEGQLYEEGVTFLSSSNPCLQ- 214
C +C C EG+++ KP PC G P +PG VT + NPC
Sbjct: 5769 CQSCVCDEGSVSVQCKPL---PCDAQGQPPPCNRPGF--------VTVTRPRAENPCCPE 5817
Query: 215 --CTCLRSRVRCMALKCPPSPCPEPVLRPGHCCPTC----QGCTEGGSHWEHGQEWTTPG 268
C C + CPP G CCPT Q C+ G+ + G T PG
Sbjct: 5818 TVCVCNTTTCPQSLPVCPPGQESICTQEEGDCCPTFRCRPQLCSYNGTFYGVGA--TFPG 5875
Query: 269 D-PCRICRCLEGH-----IQCRQREC-ASLCP--YPARPLPGTCCPVC--DGCFLNGREH 317
PC +C CL G +QC++ C + CP + + + G CC C C
Sbjct: 5876 ALPCHMCTCLSGDTQDPTVQCQEDACNNTTCPQGFEYKRVAGQCCGECVQTACLT----- 5930
Query: 318 RSGEPV--------GSGDPCSHCRC-ANGSVQC---EPLPCPPV-PCRHPGKIPGQCCPV 364
G+PV D C+ C A G V +P CP V CR + G CC
Sbjct: 5931 PDGQPVQLNETWVNSHVDNCTVYLCEAEGGVHLLTPQPASCPDVSSCRGSLRKTG-CCYS 5989
Query: 365 C--DGCE---------YQGHQYQSQETFRLQERGLCVRCSCQAGEVSCEEQEC 406
C D C+ +QG + + TF G C S + E + +C
Sbjct: 5990 CEEDSCQVRINTTILWHQGCETEVNITFC---EGSCPGASKYSAEAQAMQHQC 6039
Score = 47.8 bits (112), Expect = 4e-05
Identities = 46/156 (29%), Positives = 62/156 (39%), Gaps = 29/156 (18%)
Query: 118 VCQDGAAHCGPQAHLPHCRG--CSQNGQTYGNGETFSPDA--CTTCRCLEG-----TITC 168
+C C P CR CS NG YG G TF P A C C CL G T+ C
Sbjct: 5841 ICTQEEGDCCPTFR---CRPQLCSYNGTFYGVGATF-PGALPCHMCTCLSGDTQDPTVQC 5896
Query: 169 NQKPCPRGPCPE-------PGACCPHC-KPGC-DYEGQLYEEGVTFLSSS-NPCLQCTCL 218
+ C CP+ G CC C + C +GQ + T+++S + C C
Sbjct: 5897 QEDACNNTTCPQGFEYKRVAGQCCGECVQTACLTPDGQPVQLNETWVNSHVDNCTVYLC- 5955
Query: 219 RSRVRCMALKCPPSPCPE-----PVLRPGHCCPTCQ 249
+ L P+ CP+ LR CC +C+
Sbjct: 5956 EAEGGVHLLTPQPASCPDVSSCRGSLRKTGCCYSCE 5991
Score = 45.4 bits (106), Expect = 2e-04
Identities = 50/192 (26%), Positives = 62/192 (32%), Gaps = 45/192 (23%)
Query: 84 LESCECHPA---SPQCWGLGRAWPEGARWEPDACTACVCQDGAAHCGPQAHLPHCRG-CS 139
L SC CH S QC G P+ R PD C C CR C+
Sbjct: 303 LLSCVCHTLAEYSRQCTHAG-GLPQDWRG-PDFCPQ--------KCPNNMQYHECRSPCA 352
Query: 140 QNGQTYGNGETFSPDACTTCRCLEGTITCNQKPCPRGPCPEPGACCPHCKPGCDYEGQLY 199
+ C C EGT+ + C P K C Y G Y
Sbjct: 353 DTCSNQEHSRACEDHCVAGCFCPEGTVLDDIGQT---------GCVPVSKCACVYNGAAY 403
Query: 200 EEGVTFLSSSNPCLQCTCLRSRVRCMALKCPPSPCPEPVLRPGHCCPTCQGCTEGGSHWE 259
G T+ S C CTC R C + C PG C GG+H+
Sbjct: 404 APGATY---STDCTNCTCSGGRWSCQEVPC-----------PGTC------SVLGGAHFS 443
Query: 260 --HGQEWTTPGD 269
G+++T GD
Sbjct: 444 TFDGKQYTVHGD 455
Score = 43.5 bits (101), Expect = 8e-04
Identities = 49/203 (24%), Positives = 62/203 (30%), Gaps = 53/203 (26%)
Query: 172 PCPRGPCPEPGACCPHCKPGCDY-EGQLYEEGVTFLSSSNPCLQCTCLRSRVRCMALKCP 230
P P G C + C G + E + +L++ C Q C +CP
Sbjct: 905 PLPAGNCTDEEGICHRTLLGPAFAECHALVDSTAYLAA---CAQDLC----------RCP 951
Query: 231 PSPCPEPVLRPGHCCPTCQGCTEGGSHWEHGQEWTTPGDPCRICRCLEGHIQCRQRECAS 290
PC V C GG + W P R C H +C C
Sbjct: 952 TCPCATFVEYSRQCAHA------GGQP----RNWRCPELCPRTCPLNMQHQECGS-PCTD 1000
Query: 291 LCPYPARPL-------------PGTCCPVCDG-------------CFLNGREHRSGEPVG 324
C P R PG C V D C GR + G
Sbjct: 1001 TCSNPQRAQLCEDHCVDGCFCPPGRSCTVLDDITHSGCLPLGQCPCTHGGRTYSPGTSFN 1060
Query: 325 SGDPCSHCRCANGSVQCEPLPCP 347
+ CS C C+ G QC+ LPCP
Sbjct: 1061 T--TCSSCTCSGGLWQCQDLPCP 1081
Score = 42.4 bits (98), Expect = 0.002
Identities = 38/162 (23%), Positives = 58/162 (35%), Gaps = 28/162 (17%)
Query: 362 CPVCDGCEYQGHQYQSQETFRLQERGLCVRCSCQAGEVSCEEQECPVTPCALPASGRQLC 421
CP C + + Q C + ++ + QEC +PC S Q
Sbjct: 950 CPTCPCATFVEYSRQCAHAGGQPRNWRCPELCPRTCPLNMQHQECG-SPCTDTCSNPQRA 1008
Query: 422 PACELDGEEFAEGVQWEPDGRPCTACVCQDGVPKCGAVLCPPAPCQHPTQPPGACCPSCD 481
CE + +G + P GR CT D + G + P G C
Sbjct: 1009 QLCE---DHCVDGC-FCPPGRSCTVL---DDITHSGCL------------PLGQC----- 1044
Query: 482 SCTYHSQVYANGQNFTDADSPCHACHCQDGTVTCSLVDCPPT 523
CT+ + Y+ G +F ++ C +C C G C + CP T
Sbjct: 1045 PCTHGGRTYSPGTSF---NTTCSSCTCSGGLWQCQDLPCPGT 1083
Score = 41.2 bits (95), Expect = 0.004
Identities = 47/179 (26%), Positives = 63/179 (35%), Gaps = 37/179 (20%)
Query: 447 CVCQDGVPKC--GAVLCPPAPCQHPTQPPGACCPSCDSCTYHSQVYANGQNFTDADSPCH 504
C G+P+ G CP C + Q P D+C+ N ++ + C
Sbjct: 318 CTHAGGLPQDWRGPDFCPQK-CPNNMQYHECRSPCADTCS-------NQEHSRACEDHCV 369
Query: 505 A-CHCQDGTVTCSLVDCPPTTCARPQSGPGQCCPRCPDCILEEEVFVDGESFSHPRDPCQ 563
A C C +GTV L D T C P C C+ + G ++S C
Sbjct: 370 AGCFCPEGTV---LDDIGQTGCV-----PVSKCA----CVYNGAAYAPGATYS---TDCT 414
Query: 564 ECRCQEGHAHCQPRPCPRAPCAHPLPGTCCP-NDCSGCAFGGKEYPSGADFPHP-SDPC 620
C C G CQ PC PGTC F GK+Y D + + PC
Sbjct: 415 NCTCSGGRWSCQEVPC---------PGTCSVLGGAHFSTFDGKQYTVHGDCSYVLTKPC 464
Score = 40.4 bits (93), Expect = 0.007
Identities = 23/69 (33%), Positives = 30/69 (43%), Gaps = 8/69 (11%)
Query: 116 ACVCQDGAAHCG--PQAHLPHCRGCSQNGQTYGNGETFSPDACTTCRCLEGTITCNQKPC 173
+C D H G P P C+ G+TY G +F+ C++C C G C PC
Sbjct: 1026 SCTVLDDITHSGCLPLGQCP----CTHGGRTYSPGTSFNT-TCSSCTCSGGLWQCQDLPC 1080
Query: 174 PRGPCPEPG 182
P G C G
Sbjct: 1081 P-GTCSVQG 1088
Score = 39.7 bits (91), Expect = 0.011
Identities = 120/541 (22%), Positives = 176/541 (32%), Gaps = 110/541 (20%)
Query: 97 WGLGRAWPEGARWEPDACTACVCQDGAAH--CGPQAHLPHCRGCSQNGQTYGNGETFSPD 154
W L + P+ A D CTA + A C H P C + E D
Sbjct: 1748 WKLSPSCPD-ALAPKDPCTANPFRKSWAQKQCSI-LHGPTFAACRSQVDSTKYYEACVND 1805
Query: 155 ACTT-----CRCLEGTITCNQKPC-PRGPCPE---PGAC---CPHCKP--GCDYEGQLYE 200
AC C C + + C G C P C C P GC++ Q
Sbjct: 1806 ACACDSGGDCECFCTAVAAYAQACHDAGLCVSWRTPDTCPLFCDFYNPHGGCEWHYQ--- 1862
Query: 201 EGVTFLSSSNPCLQCTCLRSRVRCMA---------LKCPPSPCPEPVLRPGH--CCPTCQ 249
PCL+ TC C+ KCPPS +P C C
Sbjct: 1863 ------PCGAPCLK-TCRNPSGHCLVDLPGLEGCYPKCPPS---QPFFNEDQMKCVAQCG 1912
Query: 250 GCTEGGSHWEHGQEWTTPGDPCRICRCLEGHIQCRQRECASLCPYPARPLPGTCCPVCDG 309
+ G++++ G T + C+ C C IQC A C Y R
Sbjct: 1913 CYDKDGNYYDVGARVPT-AENCQSCNCTPSGIQCAHSLEACTCTYEDRTYS--------- 1962
Query: 310 CFLNGREHRSGEPVGSGDPCSHCRC-ANGSVQCEPLPCPPVPCRHP-------------- 354
+ + + +G+ C C +NG++ + + CP P P
Sbjct: 1963 --YQDVIYNTTDGLGA---CLIAICGSNGTIIRKAVACPGTPATTPFTFTTAWVPHSTTS 2017
Query: 355 GKIPGQCCPVCDGCE----YQGHQYQSQ------ETFR-LQERGLCVRCSCQAGEVSCEE 403
+P V + C Y GH+ + ETF L++RG V C A ++ C
Sbjct: 2018 PALPVSTVCVREVCRWSSWYNGHRPEPGLGGGDFETFENLRQRGYQV-CPVLA-DIECRA 2075
Query: 404 QECPVTPCALPASGRQLCPACE-LDGEEFAEGVQWEPDGRPCTACVCQD---GVPKCGAV 459
+ P P L G+Q+ C+ + G A Q P +C D V C V
Sbjct: 2076 AQLPDMP--LEELGQQV--DCDRMRGLMCANSQQSPP--------LCHDYELRVLCCEYV 2123
Query: 460 LCPPAPCQHPTQPPGACCPSCDSCTYHSQVYANGQN---FTDADSPCHACHCQDGTVTCS 516
C P+P + P + + +Q A + T + A Q G+ +
Sbjct: 2124 PCGPSPAPGTSPQPSLSASTEPAVPTPTQTTATEKTTLWVTPSIRSTAALTSQTGSSS-- 2181
Query: 517 LVDCPPTTCARPQSGPGQCCPRCPDCILEEEVFVDGESFSHPRDPCQECRCQEGHAHCQP 576
P T G C PRC +E + E + + R GH QP
Sbjct: 2182 ----GPVTVTPSAPGTTTCQPRCQWTEWFDEDYPKSEQLGGDVESYDKIRAAGGHLCQQP 2237
Query: 577 R 577
+
Sbjct: 2238 K 2238
Score = 38.1 bits (87), Expect = 0.033
Identities = 56/214 (26%), Positives = 69/214 (32%), Gaps = 46/214 (21%)
Query: 495 NFTDADSPCHACHCQDGTVTC-SLVDCPPTTCARPQSGPGQC-CPRCPDCILEEEVFVDG 552
N TD + CH C +LVD A Q C CP CP E
Sbjct: 910 NCTDEEGICHRTLLGPAFAECHALVDSTAYLAACAQD---LCRCPTCPCATFVEYSRQCA 966
Query: 553 ESFSHPRDPCQECRCQEGHAHCQPRPCPRAPCAHPLPGTCCPNDCSGCAFGGKEYPSGAD 612
+ PR+ RC E PR CP H G+ C + CS
Sbjct: 967 HAGGQPRN----WRCPE----LCPRTCP-LNMQHQECGSPCTDTCSN------------- 1004
Query: 613 FPHPSDPCRLCRCLSGNVQCLARRCVPLPCPEPVLLPGECCP--QCPAAPAPAGCPRPGA 670
P + C C+ G R C L + + G C P QCP C G
Sbjct: 1005 -PQRAQLCE-DHCVDGCFCPPGRSCTVL---DDITHSG-CLPLGQCP-------CTHGGR 1051
Query: 671 AHARHQEYFSPPGDPCRRCLCLDGSVSCQRLPCP 704
++ + C C C G CQ LPCP
Sbjct: 1052 TYSPGTSF----NTTCSSCTCSGGLWQCQDLPCP 1081
Score = 37.7 bits (86), Expect = 0.043
Identities = 30/112 (26%), Positives = 40/112 (35%), Gaps = 6/112 (5%)
Query: 594 PNDCSGCAFGGKEYPSGADFPHPSDPCR-LCRCLSGNVQCLARRCVPLPCPEPVLLPGEC 652
P D G F ++ P+ + PC C + C CPE +L
Sbjct: 325 PQDWRGPDFCPQKCPNNMQYHECRSPCADTCSNQEHSRACEDHCVAGCFCPEGTVLDDIG 384
Query: 653 CPQCPAAPAPAGCPRPGAAHARHQEYFSPPGDPCRRCLCLDGSVSCQRLPCP 704
C + C GAA+A Y + C C C G SCQ +PCP
Sbjct: 385 QTGCVPV-SKCACVYNGAAYAPGATYSTD----CTNCTCSGGRWSCQEVPCP 431
Score = 37.0 bits (84), Expect = 0.074
Identities = 41/147 (27%), Positives = 48/147 (32%), Gaps = 37/147 (25%)
Query: 332 CRC---ANGSVQCEPLPCPPVPCRHPGKIPGQC----------CPVCDGCEYQGHQYQSQ 378
C C A S QC P R P P +C P D C Q H
Sbjct: 306 CVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCADTCSNQEHS---- 361
Query: 379 ETFRLQERGLCVRCSCQAGEVSCE--EQEC-PVTPCALPASGRQLCPACELDGEEFAEGV 435
R E C C G V + + C PV+ CA C +G +A G
Sbjct: 362 ---RACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCA-----------CVYNGAAYAPGA 407
Query: 436 QWEPDGRPCTACVCQDGVPKCGAVLCP 462
+ D CT C C G C V CP
Sbjct: 408 TYSTD---CTNCTCSGGRWSCQEVPCP 431
Score = 36.6 bits (83), Expect = 0.096
Identities = 46/210 (21%), Positives = 64/210 (30%), Gaps = 50/210 (23%)
Query: 230 PPSPCPEPVLRPGHCCPT----------------CQGCTEGGSHWEHGQEWTTPGDPCRI 273
P C +PV P C T C + GS+ E ++ + +
Sbjct: 244 PTEQCQDPVPEPPRNCSTGFGICEELLHGQLFSGCVALVDVGSYLEACRQDLCFCEDTDL 303
Query: 274 CRCLEGHIQCRQRECASLCPYPARPLPGTCCPVCDGCFLNGREHRSGEPVGSGDPCSH-- 331
C+ + R+C P CP C N + H P D CS+
Sbjct: 304 LSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCP--QKCPNNMQYHECRSPCA--DTCSNQE 359
Query: 332 ------------CRCANGSVQCEPLPCPPVPCRHPGKIPGQCCPVCDGCEYQGHQYQSQE 379
C C G+V + G +P C C Y G Y
Sbjct: 360 HSRACEDHCVAGCFCPEGTVLDD--------IGQTGCVPVSKC----ACVYNGAAYAPGA 407
Query: 380 TFRLQERGLCVRCSCQAGEVSCEEQECPVT 409
T+ C C+C G SC+E CP T
Sbjct: 408 TYSTD----CTNCTCSGGRWSCQEVPCPGT 433
Score = 35.8 bits (81), Expect = 0.16
Identities = 38/155 (24%), Positives = 45/155 (29%), Gaps = 44/155 (28%)
Query: 636 RCVPLPCPEPVLLPGECCP---QCPAAPAPAGCPRPGAAHARHQEYFSPPGDPC------ 686
RC PC V +C Q P CPR + +HQE SP D C
Sbjct: 949 RCPTCPCATFVEYSRQCAHAGGQPRNWRCPELCPRTCPLNMQHQECGSPCTDTCSNPQRA 1008
Query: 687 ----------------RRCLCLDGSVSCQRLPCPPAPCAHPRQGPCCPSCDGCLYQGKEF 730
R C LD LP PC H G+ +
Sbjct: 1009 QLCEDHCVDGCFCPPGRSCTVLDDITHSGCLPLGQCPCTH---------------GGRTY 1053
Query: 731 ASGERFPSPTAACHLCLCWEGSVSCEPKACAPALC 765
+ G F C C C G C+ C P C
Sbjct: 1054 SPGTSF---NTTCSSCTCSGGLWQCQDLPC-PGTC 1084
Score = 34.7 bits (78), Expect = 0.37
Identities = 41/144 (28%), Positives = 49/144 (34%), Gaps = 16/144 (11%)
Query: 156 CTTCRCLEGTITCNQKPCPR-GPCPEPGACCPHCKPGCDYEGQLYEEGVTFLSS-SNPCL 213
C TC C T + C G P C C C Q E G + SNP
Sbjct: 950 CPTCPC--ATFVEYSRQCAHAGGQPRNWRCPELCPRTCPLNMQHQECGSPCTDTCSNPQR 1007
Query: 214 QCTCLRSRVRCM-ALKCPPS-PCP--EPVLRPGHCCPTCQ-GCTEGGSHWEHGQEWTTPG 268
C C+ CPP C + + G C P Q CT GG + G + T
Sbjct: 1008 AQLC---EDHCVDGCFCPPGRSCTVLDDITHSG-CLPLGQCPCTHGGRTYSPGTSFNTT- 1062
Query: 269 DPCRICRCLEGHIQCRQRECASLC 292
C C C G QC+ C C
Sbjct: 1063 --CSSCTCSGGLWQCQDLPCPGTC 1084
Score = 33.5 bits (75), Expect = 0.81
Identities = 49/208 (23%), Positives = 61/208 (29%), Gaps = 47/208 (22%)
Query: 117 CVCQDG-----AAHCGPQAHLPHCRGCSQNGQTYGNGETFSPDACTTCRCLEGTITCNQK 171
C C G A C P P C +G GE D C C G ++C
Sbjct: 1391 CTCPAGTFLNDAGACVPAQECP----CYAHGTVLAPGEVVH-DEGAVCSCTGGKLSCLGA 1445
Query: 172 PCPRGPCPEPGACCPHCKPGCDYEGQLYEEGVTFLSSSNPCLQC--TCLRSRVRCMALKC 229
+ G P C S+ P +C +C V C + C
Sbjct: 1446 SLQKST----GCAAPMVYLDCSNS-----------SAGTPGAECLRSCHTLDVGCFSTHC 1490
Query: 230 PPSPCPEPVLRPGHCCPTCQGC-TEGGSHWEHGQEWTTPGDP----CRICRCLEGHIQCR 284
S C P PG GC E H + PG+ C C C +C
Sbjct: 1491 V-SGCVCP---PGLVSDGSGGCIAEEDCPCVHNEATYKPGETIRVDCNTCTCRNRRWECS 1546
Query: 285 QRECASLCPYPARPLPGTCCPVCDGCFL 312
R C GTC DG F+
Sbjct: 1547 HRLCL-----------GTCVAYGDGHFI 1563
Score = 30.8 bits (68), Expect = 5.3
Identities = 73/325 (22%), Positives = 97/325 (29%), Gaps = 93/325 (28%)
Query: 215 CTCLRSR-VRCMALKCPPSPCPEPVL-----RPGHCCPTCQGCTEGGSHWEHGQEWTTPG 268
C C RS C AL C + R G C Q C + Q +
Sbjct: 1312 CNCERSEDCLCAALSSYVHACAAKGVQLSDWRDGVCTKYMQNCPKS-------QRYAYVV 1364
Query: 269 DPCR-ICRCLEGHIQCRQRECASLCPYPARPLPGTCCPVCDGCFLNGREHRSGEPVGSGD 327
D C+ CR L E C P+ G CP G FLN G+
Sbjct: 1365 DACQPTCRGLS--------EADVTCSVSFVPVDGCTCPA--GTFLND--------AGACV 1406
Query: 328 PCSHCRC-ANGSVQCEPLPCPPVPCRHPGKIPGQCCPVCDGCEYQGHQYQSQETFRLQER 386
P C C A+G+V PG++ + +
Sbjct: 1407 PAQECPCYAHGTVLA------------PGEV-------------------------VHDE 1429
Query: 387 GLCVRCSCQAGEVSCEEQECPVTPCALPASGRQLCPACELDGEEFAEGVQWEPDGRPC-- 444
G CSC G++SC +L S P LD + G R C
Sbjct: 1430 GAV--CSCTGGKLSC-------LGASLQKSTGCAAPMVYLDCSNSSAGTPGAECLRSCHT 1480
Query: 445 --TACVCQDGVPKCGAVLCPPAPCQHPTQPPGACCPSCD-SCTYHSQVYANGQNFTDADS 501
C V C +CPP + G C D C ++ Y G+
Sbjct: 1481 LDVGCFSTHCVSGC---VCPPGLV---SDGSGGCIAEEDCPCVHNEATYKPGETIR---V 1531
Query: 502 PCHACHCQDGTVTCSLVDCPPTTCA 526
C+ C C++ CS C T A
Sbjct: 1532 DCNTCTCRNRRWECSHRLCLGTCVA 1556
Score = 30.4 bits (67), Expect = 6.9
Identities = 48/200 (24%), Positives = 64/200 (32%), Gaps = 27/200 (13%)
Query: 454 PKCGAVLCPPAPCQHPTQPPGACCPSCDSCTY-HSQVYANGQNFTDADS---PC--HACH 507
P C L P PC T P + C+ H +A ++ D+ C AC
Sbjct: 1752 PSCPDALAPKDPC---TANPFRKSWAQKQCSILHGPTFAACRSQVDSTKYYEACVNDACA 1808
Query: 508 CQDGTVTCSLVDCPPTTCARPQSGPGQCCP-RCPD-CILEEEVFVDGESFSHPRDPC--- 562
C G C A+ G C R PD C L + + PC
Sbjct: 1809 CDSGG-DCECFCTAVAAYAQACHDAGLCVSWRTPDTCPLFCDFYNPHGGCEWHYQPCGAP 1867
Query: 563 --QECRCQEGHA--------HCQPRPCPRAPCAHPLPGTCCPNDCSGCAFGGKEYPSGAD 612
+ CR GH C P+ CP + C C G Y GA
Sbjct: 1868 CLKTCRNPSGHCLVDLPGLEGCYPK-CPPSQPFFNEDQMKCVAQCGCYDKDGNYYDVGAR 1926
Query: 613 FPHPSDPCRLCRCLSGNVQC 632
P ++ C+ C C +QC
Sbjct: 1927 VP-TAENCQSCNCTPSGIQC 1945
>gi|119466532 laminin alpha 2 subunit isoform b precursor [Homo
sapiens]
Length = 3118
Score = 80.1 bits (196), Expect = 8e-15
Identities = 134/567 (23%), Positives = 180/567 (31%), Gaps = 131/567 (23%)
Query: 118 VCQDGAAHCGPQAHLPHCRGCSQNGQTYGNGETFSPDACTTCRCLEGTITCNQKPCPRGP 177
VCQ + G R NG +G C C+C +C+
Sbjct: 723 VCQCPPGYTGSSCESCWPRHRRVNGTIFGG-------ICEPCQCFGHAESCDDVTGECLN 775
Query: 178 CPEP--GACCPHCKPGCDYEGQLYEEGVTFLSSSNPCLQCTCLRSRV-----------RC 224
C + G C C PG Y E +S C C C + R
Sbjct: 776 CKDHTGGPYCDKCLPG------FYGEPTK--GTSEDCQPCACPLNIPSNNFSPTCHLDRS 827
Query: 225 MALKCPPSPCPEPVLRPGHCCPTCQGCTEGGSHWEHGQEWTTPGDPCRICRCLEGHIQCR 284
+ L C P G+ P C+ C EG GQ + PG C+ C+C +
Sbjct: 828 LGLICDGCPV-------GYTGPRCERCAEG----YFGQP-SVPGGSCQPCQCNDNLDFSI 875
Query: 285 QRECASLCPYPARPLPGTCCPVCDGCFLNGREHRSGEPVGSGDPCSHCRCANGSVQCEPL 344
C SL PGT C+ C + G+ V + + C CRC G E
Sbjct: 876 PGSCDSLSGSCLICKPGTTGRYCELC----ADGYFGDAVDAKN-CQPCRCNAGGSFSEVC 930
Query: 345 PCPPVPCRHPGKIPGQCCPVCDGCEYQGHQYQSQETFRLQERGLCVRCSCQA-GEVSCEE 403
C + GQ C C TF LQ CV C+C + G S +
Sbjct: 931 HSQTGQCECRANVQGQRCDKC-----------KAGTFGLQSARGCVPCNCNSFGSKSFDC 979
Query: 404 QECPVTPCALPASGRQLCPACELDGEEFAEGVQWEPDGRPCTACVC----QDGVPKCGAV 459
+E C +G++ C C F EG CTAC C + PK G
Sbjct: 980 EESGQCWCQPGVTGKK-CDRCAHGYFNFQEG--------GCTACECSHLGNNCDPKTGRC 1030
Query: 460 LCPPAPCQHPTQPPGACCPSCDSCTYHSQVYANGQNFTDADSPCHACHCQ-------DGT 512
+CPP G C C T+ G + T + C AC+C
Sbjct: 1031 ICPP-------NTIGEKCSKCAPNTW-------GHSIT---TGCKACNCSTVGSLDFQCN 1073
Query: 513 VTCSLVDCPP-------TTCARPQSGPGQCCPRCPDCILEEEVFVDGESFSHPRDPCQEC 565
V +C P T C+R PRC C + F+ G + ++C
Sbjct: 1074 VNTGQCNCHPKFSGAKCTECSRGHWN----YPRCNLC----DCFLPGTDATTCDSETKKC 1125
Query: 566 RCQEGHAHCQPRPCPRAPCAHPLPGTCCPNDCSGCAFGGKEYPSGADFPHPSDPCRLCRC 625
C + C C + G C C G G D +P C C C
Sbjct: 1126 SCSDQTGQC--------TCKVNVEGI----HCDRCRPG----KFGLDAKNPLG-CSSCYC 1168
Query: 626 LSGNVQC-----LARRCVPLPCPEPVL 647
QC L R V L + +L
Sbjct: 1169 FGTTTQCSEAKGLIRTWVTLKAEQTIL 1195
Score = 52.8 bits (125), Expect = 1e-06
Identities = 91/377 (24%), Positives = 118/377 (31%), Gaps = 81/377 (21%)
Query: 454 PKCGAVLCPPAPCQHPTQPPGACCPSCDSCTYHSQVYANGQNFTDADSPC----HACHCQ 509
P G++ CQ P G+ C SC H +V NG F PC HA C
Sbjct: 712 PTDGSIAAAVEVCQCPPGYTGSSCESC--WPRHRRV--NGTIFGGICEPCQCFGHAESCD 767
Query: 510 DGTVTC----------SLVDCPPTTCARPQSGPGQCCPRC------------PDCILEEE 547
D T C C P P G + C C P C L+
Sbjct: 768 DVTGECLNCKDHTGGPYCDKCLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSPTCHLDRS 827
Query: 548 --VFVDGESFSHPRDPCQECRCQEGH--------AHCQPRPCPRAPCAHPLPGTC--CPN 595
+ DG + C+ RC EG+ CQP C +PG+C
Sbjct: 828 LGLICDGCPVGYTGPRCE--RCAEGYFGQPSVPGGSCQPCQC-NDNLDFSIPGSCDSLSG 884
Query: 596 DCSGCAFG--GKEYPSGAD--FPHPSDP--CRLCRCLSGNVQCLARRCVPLPCPEPVLLP 649
C C G G+ AD F D C+ CRC +G C +
Sbjct: 885 SCLICKPGTTGRYCELCADGYFGDAVDAKNCQPCRCNAGGSFSEVCHSQTGQCECRANVQ 944
Query: 650 GECCPQCPAAPAPAGCPRPGAAHARHQEYFSPPGDPCRRCLCLDGSVSCQRLPCPPAPCA 709
G+ C +C A G AR C C C S + C +
Sbjct: 945 GQRCDKCKAGTF-------GLQSAR----------GCVPCNC--NSFGSKSFDCEESGQC 985
Query: 710 HPRQGPCCPSCDGCLYQGKEFASGERFPSPTAACHLCLCWEGSVSCEPKACAPALCPFPA 769
+ G CD C + F G C C C +C+PK +CP
Sbjct: 986 WCQPGVTGKKCDRCAHGYFNFQEG--------GCTACECSHLGNNCDPKT-GRCICPPNT 1036
Query: 770 RGDCCPDC--DGEGHGI 784
G+ C C + GH I
Sbjct: 1037 IGEKCSKCAPNTWGHSI 1053
Score = 39.3 bits (90), Expect = 0.015
Identities = 51/207 (24%), Positives = 62/207 (29%), Gaps = 34/207 (16%)
Query: 525 CARPQSGPGQCCPRCPDCILEEEVFVDGESFSHPRDPCQECRCQEGHAHCQPRPCPRAPC 584
C P G C C G + C C+C + C P C
Sbjct: 1380 CDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQNC 1439
Query: 585 AHPLPGTCCPNDCSGCAFGGKEYPSGADFPHPSDPCRLCRC----LSGNV--QCLARRCV 638
H G + C CA G G P+D C+ C C S N C+A
Sbjct: 1440 QHHTAG----DFCERCALGYYGIVKGL----PND-CQQCACPLISSSNNFSPSCVAEGLD 1490
Query: 639 PLPCPE-PVLLPGECCPQCPAAPAPAGCPRPGAAHARHQEYFSPPGDPCRRCLCLDGSVS 697
C P G+ C +C AP G P PG C+ C C
Sbjct: 1491 DYRCTACPRGYEGQYCERC--APGYTGSP-------------GNPGGSCQECEC--DPYG 1533
Query: 698 CQRLPCPPAP-CAHPRQGPCCPSCDGC 723
+PC P R G CDGC
Sbjct: 1534 SLPVPCDPVTGFCTCRPGATGRKCDGC 1560
Score = 35.8 bits (81), Expect = 0.16
Identities = 36/146 (24%), Positives = 44/146 (30%), Gaps = 31/146 (21%)
Query: 355 GKIPGQCCPVCDGCEYQGHQYQSQETFRLQERGLCVRCSCQAGEVSCEE----------- 403
G+ PG C C+ GH E +C C CE
Sbjct: 1407 GRTPGPTLGTCVPCQCNGHSSLCD-----PETSICQNCQHHTAGDFCERCALGYYGIVKG 1461
Query: 404 --QECPVTPCALPASGRQLCPACELDGEEFAEGVQWEPDGRPCTACVCQDGVPKCGAVLC 461
+C C L +S P+C AEG+ D CTA C G C
Sbjct: 1462 LPNDCQQCACPLISSSNNFSPSC------VAEGL----DDYRCTA--CPRGYEGQYCERC 1509
Query: 462 PPAPCQHPTQPPGACCPSCDSCTYHS 487
P P PG C C+ Y S
Sbjct: 1510 APGYTGSPGN-PGGSCQECECDPYGS 1534
Score = 33.1 bits (74), Expect = 1.1
Identities = 22/69 (31%), Positives = 27/69 (39%), Gaps = 3/69 (4%)
Query: 719 SCDGCL--YQGKEFASGERFPSPT-AACHLCLCWEGSVSCEPKACAPALCPFPARGDCCP 775
SC+ CL + G R P PT C C C S C+P+ C GD C
Sbjct: 1390 SCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQNCQHHTAGDFCE 1449
Query: 776 DCDGEGHGI 784
C +GI
Sbjct: 1450 RCALGYYGI 1458
Score = 30.8 bits (68), Expect = 5.3
Identities = 55/220 (25%), Positives = 73/220 (33%), Gaps = 61/220 (27%)
Query: 161 CLEGTITCNQKPCPRGPCPEPGACCPHCKPG----CDYEGQLYEEGVTFLSSSNPCLQCT 216
CL G +P R P P G C P G CD E + + ++ + C +C
Sbjct: 1394 CLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSIC-QNCQHHTAGDFCERCA 1452
Query: 217 C-LRSRVRCMALKCPPSPCPEPVLRPGHCCPTCQGCTEGGSHWEHGQEWTTPGDPCRICR 275
V+ + C CP + + P+C EG + R
Sbjct: 1453 LGYYGIVKGLPNDCQQCACP-LISSSNNFSPSC--VAEGLDDY----------------R 1493
Query: 276 CLEGHIQCRQRECASLCPYPARPLPGTCCPVCDGCFLNGREHRSGEPVGSGDPCSHCRC- 334
C + CP R G C C G G P GS C C C
Sbjct: 1494 C-------------TACP---RGYEGQYCERC----APGYTGSPGNPGGS---CQECECD 1530
Query: 335 ANGSVQCEPLPCPPV----PCRHPGKIPGQCCPVCDGCEY 370
GS+ P+PC PV CR PG CDGC++
Sbjct: 1531 PYGSL---PVPCDPVTGFCTCR-----PGATGRKCDGCKH 1562
Score = 30.0 bits (66), Expect = 9.0
Identities = 27/111 (24%), Positives = 32/111 (28%), Gaps = 10/111 (9%)
Query: 638 VPLPCPEPVLLPGECCPQCPAAPAPAGCPRPGAAHARHQEYFSPPGDPCRRCLCLDGSVS 697
V P + E C QCP + C H R G C C C + S
Sbjct: 709 VSYPTDGSIAAAVEVC-QCPPGYTGSSCESCWPRHRRVNGTIF--GGICEPCQCFGHAES 765
Query: 698 CQRLPCPPAPCAHPRQGPCCPSCDGCLYQGKEFASGERFPSPTAACHLCLC 748
C + C GP C C Y GE + C C C
Sbjct: 766 CDDVTGECLNCKDHTGGPYCDKCLPGFY-------GEPTKGTSEDCQPCAC 809
Score = 30.0 bits (66), Expect = 9.0
Identities = 35/135 (25%), Positives = 44/135 (32%), Gaps = 30/135 (22%)
Query: 109 WEPDACTACVC---------QDGAAHCGPQAHLPHCRGCSQNGQTYGNGETFSPDACTTC 159
++ CTAC C + G C P C C+ N T+G+ T AC
Sbjct: 1006 FQEGGCTACECSHLGNNCDPKTGRCICPPNTIGEKCSKCAPN--TWGHSITTGCKACNCS 1063
Query: 160 -------RCLEGTITCNQKP---------CPRGPCPEPGA-CCPHCKPGCDYEGQLYEEG 202
+C T CN P C RG P C PG D +
Sbjct: 1064 TVGSLDFQCNVNTGQCNCHPKFSGAKCTECSRGHWNYPRCNLCDCFLPGTD--ATTCDSE 1121
Query: 203 VTFLSSSNPCLQCTC 217
S S+ QCTC
Sbjct: 1122 TKKCSCSDQTGQCTC 1136
>gi|28559088 laminin alpha 2 subunit isoform a precursor [Homo
sapiens]
Length = 3122
Score = 80.1 bits (196), Expect = 8e-15
Identities = 134/567 (23%), Positives = 180/567 (31%), Gaps = 131/567 (23%)
Query: 118 VCQDGAAHCGPQAHLPHCRGCSQNGQTYGNGETFSPDACTTCRCLEGTITCNQKPCPRGP 177
VCQ + G R NG +G C C+C +C+
Sbjct: 723 VCQCPPGYTGSSCESCWPRHRRVNGTIFGG-------ICEPCQCFGHAESCDDVTGECLN 775
Query: 178 CPEP--GACCPHCKPGCDYEGQLYEEGVTFLSSSNPCLQCTCLRSRV-----------RC 224
C + G C C PG Y E +S C C C + R
Sbjct: 776 CKDHTGGPYCDKCLPG------FYGEPTK--GTSEDCQPCACPLNIPSNNFSPTCHLDRS 827
Query: 225 MALKCPPSPCPEPVLRPGHCCPTCQGCTEGGSHWEHGQEWTTPGDPCRICRCLEGHIQCR 284
+ L C P G+ P C+ C EG GQ + PG C+ C+C +
Sbjct: 828 LGLICDGCPV-------GYTGPRCERCAEG----YFGQP-SVPGGSCQPCQCNDNLDFSI 875
Query: 285 QRECASLCPYPARPLPGTCCPVCDGCFLNGREHRSGEPVGSGDPCSHCRCANGSVQCEPL 344
C SL PGT C+ C + G+ V + + C CRC G E
Sbjct: 876 PGSCDSLSGSCLICKPGTTGRYCELC----ADGYFGDAVDAKN-CQPCRCNAGGSFSEVC 930
Query: 345 PCPPVPCRHPGKIPGQCCPVCDGCEYQGHQYQSQETFRLQERGLCVRCSCQA-GEVSCEE 403
C + GQ C C TF LQ CV C+C + G S +
Sbjct: 931 HSQTGQCECRANVQGQRCDKC-----------KAGTFGLQSARGCVPCNCNSFGSKSFDC 979
Query: 404 QECPVTPCALPASGRQLCPACELDGEEFAEGVQWEPDGRPCTACVC----QDGVPKCGAV 459
+E C +G++ C C F EG CTAC C + PK G
Sbjct: 980 EESGQCWCQPGVTGKK-CDRCAHGYFNFQEG--------GCTACECSHLGNNCDPKTGRC 1030
Query: 460 LCPPAPCQHPTQPPGACCPSCDSCTYHSQVYANGQNFTDADSPCHACHCQ-------DGT 512
+CPP G C C T+ G + T + C AC+C
Sbjct: 1031 ICPP-------NTIGEKCSKCAPNTW-------GHSIT---TGCKACNCSTVGSLDFQCN 1073
Query: 513 VTCSLVDCPP-------TTCARPQSGPGQCCPRCPDCILEEEVFVDGESFSHPRDPCQEC 565
V +C P T C+R PRC C + F+ G + ++C
Sbjct: 1074 VNTGQCNCHPKFSGAKCTECSRGHWN----YPRCNLC----DCFLPGTDATTCDSETKKC 1125
Query: 566 RCQEGHAHCQPRPCPRAPCAHPLPGTCCPNDCSGCAFGGKEYPSGADFPHPSDPCRLCRC 625
C + C C + G C C G G D +P C C C
Sbjct: 1126 SCSDQTGQC--------TCKVNVEGI----HCDRCRPG----KFGLDAKNPLG-CSSCYC 1168
Query: 626 LSGNVQC-----LARRCVPLPCPEPVL 647
QC L R V L + +L
Sbjct: 1169 FGTTTQCSEAKGLIRTWVTLKAEQTIL 1195
Score = 52.8 bits (125), Expect = 1e-06
Identities = 91/377 (24%), Positives = 118/377 (31%), Gaps = 81/377 (21%)
Query: 454 PKCGAVLCPPAPCQHPTQPPGACCPSCDSCTYHSQVYANGQNFTDADSPC----HACHCQ 509
P G++ CQ P G+ C SC H +V NG F PC HA C
Sbjct: 712 PTDGSIAAAVEVCQCPPGYTGSSCESC--WPRHRRV--NGTIFGGICEPCQCFGHAESCD 767
Query: 510 DGTVTC----------SLVDCPPTTCARPQSGPGQCCPRC------------PDCILEEE 547
D T C C P P G + C C P C L+
Sbjct: 768 DVTGECLNCKDHTGGPYCDKCLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSPTCHLDRS 827
Query: 548 --VFVDGESFSHPRDPCQECRCQEGH--------AHCQPRPCPRAPCAHPLPGTC--CPN 595
+ DG + C+ RC EG+ CQP C +PG+C
Sbjct: 828 LGLICDGCPVGYTGPRCE--RCAEGYFGQPSVPGGSCQPCQC-NDNLDFSIPGSCDSLSG 884
Query: 596 DCSGCAFG--GKEYPSGAD--FPHPSDP--CRLCRCLSGNVQCLARRCVPLPCPEPVLLP 649
C C G G+ AD F D C+ CRC +G C +
Sbjct: 885 SCLICKPGTTGRYCELCADGYFGDAVDAKNCQPCRCNAGGSFSEVCHSQTGQCECRANVQ 944
Query: 650 GECCPQCPAAPAPAGCPRPGAAHARHQEYFSPPGDPCRRCLCLDGSVSCQRLPCPPAPCA 709
G+ C +C A G AR C C C S + C +
Sbjct: 945 GQRCDKCKAGTF-------GLQSAR----------GCVPCNC--NSFGSKSFDCEESGQC 985
Query: 710 HPRQGPCCPSCDGCLYQGKEFASGERFPSPTAACHLCLCWEGSVSCEPKACAPALCPFPA 769
+ G CD C + F G C C C +C+PK +CP
Sbjct: 986 WCQPGVTGKKCDRCAHGYFNFQEG--------GCTACECSHLGNNCDPKT-GRCICPPNT 1036
Query: 770 RGDCCPDC--DGEGHGI 784
G+ C C + GH I
Sbjct: 1037 IGEKCSKCAPNTWGHSI 1053
Score = 39.3 bits (90), Expect = 0.015
Identities = 51/207 (24%), Positives = 62/207 (29%), Gaps = 34/207 (16%)
Query: 525 CARPQSGPGQCCPRCPDCILEEEVFVDGESFSHPRDPCQECRCQEGHAHCQPRPCPRAPC 584
C P G C C G + C C+C + C P C
Sbjct: 1380 CDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQNC 1439
Query: 585 AHPLPGTCCPNDCSGCAFGGKEYPSGADFPHPSDPCRLCRC----LSGNV--QCLARRCV 638
H G + C CA G G P+D C+ C C S N C+A
Sbjct: 1440 QHHTAG----DFCERCALGYYGIVKGL----PND-CQQCACPLISSSNNFSPSCVAEGLD 1490
Query: 639 PLPCPE-PVLLPGECCPQCPAAPAPAGCPRPGAAHARHQEYFSPPGDPCRRCLCLDGSVS 697
C P G+ C +C AP G P PG C+ C C
Sbjct: 1491 DYRCTACPRGYEGQYCERC--APGYTGSP-------------GNPGGSCQECEC--DPYG 1533
Query: 698 CQRLPCPPAP-CAHPRQGPCCPSCDGC 723
+PC P R G CDGC
Sbjct: 1534 SLPVPCDPVTGFCTCRPGATGRKCDGC 1560
Score = 35.8 bits (81), Expect = 0.16
Identities = 36/146 (24%), Positives = 44/146 (30%), Gaps = 31/146 (21%)
Query: 355 GKIPGQCCPVCDGCEYQGHQYQSQETFRLQERGLCVRCSCQAGEVSCEE----------- 403
G+ PG C C+ GH E +C C CE
Sbjct: 1407 GRTPGPTLGTCVPCQCNGHSSLCD-----PETSICQNCQHHTAGDFCERCALGYYGIVKG 1461
Query: 404 --QECPVTPCALPASGRQLCPACELDGEEFAEGVQWEPDGRPCTACVCQDGVPKCGAVLC 461
+C C L +S P+C AEG+ D CTA C G C
Sbjct: 1462 LPNDCQQCACPLISSSNNFSPSC------VAEGL----DDYRCTA--CPRGYEGQYCERC 1509
Query: 462 PPAPCQHPTQPPGACCPSCDSCTYHS 487
P P PG C C+ Y S
Sbjct: 1510 APGYTGSPGN-PGGSCQECECDPYGS 1534
Score = 33.1 bits (74), Expect = 1.1
Identities = 22/69 (31%), Positives = 27/69 (39%), Gaps = 3/69 (4%)
Query: 719 SCDGCL--YQGKEFASGERFPSPT-AACHLCLCWEGSVSCEPKACAPALCPFPARGDCCP 775
SC+ CL + G R P PT C C C S C+P+ C GD C
Sbjct: 1390 SCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQNCQHHTAGDFCE 1449
Query: 776 DCDGEGHGI 784
C +GI
Sbjct: 1450 RCALGYYGI 1458
Score = 30.8 bits (68), Expect = 5.3
Identities = 55/220 (25%), Positives = 73/220 (33%), Gaps = 61/220 (27%)
Query: 161 CLEGTITCNQKPCPRGPCPEPGACCPHCKPG----CDYEGQLYEEGVTFLSSSNPCLQCT 216
CL G +P R P P G C P G CD E + + ++ + C +C
Sbjct: 1394 CLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSIC-QNCQHHTAGDFCERCA 1452
Query: 217 C-LRSRVRCMALKCPPSPCPEPVLRPGHCCPTCQGCTEGGSHWEHGQEWTTPGDPCRICR 275
V+ + C CP + + P+C EG + R
Sbjct: 1453 LGYYGIVKGLPNDCQQCACP-LISSSNNFSPSC--VAEGLDDY----------------R 1493
Query: 276 CLEGHIQCRQRECASLCPYPARPLPGTCCPVCDGCFLNGREHRSGEPVGSGDPCSHCRC- 334
C + CP R G C C G G P GS C C C
Sbjct: 1494 C-------------TACP---RGYEGQYCERC----APGYTGSPGNPGGS---CQECECD 1530
Query: 335 ANGSVQCEPLPCPPV----PCRHPGKIPGQCCPVCDGCEY 370
GS+ P+PC PV CR PG CDGC++
Sbjct: 1531 PYGSL---PVPCDPVTGFCTCR-----PGATGRKCDGCKH 1562
Score = 30.0 bits (66), Expect = 9.0
Identities = 27/111 (24%), Positives = 32/111 (28%), Gaps = 10/111 (9%)
Query: 638 VPLPCPEPVLLPGECCPQCPAAPAPAGCPRPGAAHARHQEYFSPPGDPCRRCLCLDGSVS 697
V P + E C QCP + C H R G C C C + S
Sbjct: 709 VSYPTDGSIAAAVEVC-QCPPGYTGSSCESCWPRHRRVNGTIF--GGICEPCQCFGHAES 765
Query: 698 CQRLPCPPAPCAHPRQGPCCPSCDGCLYQGKEFASGERFPSPTAACHLCLC 748
C + C GP C C Y GE + C C C
Sbjct: 766 CDDVTGECLNCKDHTGGPYCDKCLPGFY-------GEPTKGTSEDCQPCAC 809
Score = 30.0 bits (66), Expect = 9.0
Identities = 35/135 (25%), Positives = 44/135 (32%), Gaps = 30/135 (22%)
Query: 109 WEPDACTACVC---------QDGAAHCGPQAHLPHCRGCSQNGQTYGNGETFSPDACTTC 159
++ CTAC C + G C P C C+ N T+G+ T AC
Sbjct: 1006 FQEGGCTACECSHLGNNCDPKTGRCICPPNTIGEKCSKCAPN--TWGHSITTGCKACNCS 1063
Query: 160 -------RCLEGTITCNQKP---------CPRGPCPEPGA-CCPHCKPGCDYEGQLYEEG 202
+C T CN P C RG P C PG D +
Sbjct: 1064 TVGSLDFQCNVNTGQCNCHPKFSGAKCTECSRGHWNYPRCNLCDCFLPGTD--ATTCDSE 1121
Query: 203 VTFLSSSNPCLQCTC 217
S S+ QCTC
Sbjct: 1122 TKKCSCSDQTGQCTC 1136
>gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens]
Length = 5765
Score = 80.1 bits (196), Expect = 8e-15
Identities = 103/408 (25%), Positives = 137/408 (33%), Gaps = 112/408 (27%)
Query: 329 CSHCRCANGSVQCEPLPCPPVPCRHPGKIPGQCCPVCDGCEYQGHQYQSQETFRLQERGL 388
CS R A G + C+ L CPP P C P+ +Q E G+
Sbjct: 5347 CSDWRGATGGL-CD-LTCPPTKVYKP------CGPIQPATCNSRNQSPQLE-------GM 5391
Query: 389 CVRCSCQAGEVSCEEQECPVTPCALPASGRQLCPACELDGEEFAEGVQWEPDGRPCTACV 448
C C ++ + C Q CP DG G +W + C +CV
Sbjct: 5392 AEGCFCPEDQILFNAH---MGICV------QACPCVGPDGFPKFPGERWVSN---CQSCV 5439
Query: 449 CQDGVPKCGAVLCPPAPCQHPTQPPGACCPSCDSCTYHSQVYANGQNFTDADSPCHACHC 508
C +G +V C P PC QPP P + T A++PC C
Sbjct: 5440 CDEGSV---SVQCKPLPCDAQGQPPPCNRPGFVTVTRPR-----------AENPC----C 5481
Query: 509 QDGTVTCSLVDCPPTTCARPQSGPGQCCPRCPDCILEEEVFVDGESFSHPRDPCQECRCQ 568
+ C+ CP Q P CP P QE C
Sbjct: 5482 PETVCVCNTTTCP------------QSLPVCP--------------------PGQESICT 5509
Query: 569 EGHAHCQPRPCPRAPCAHPLPGTCCPNDCSGCAFGGKEYPSGADFPHPSDPCRLCRCLSG 628
+ C CP C L C++ G Y GA FP PC +C CLSG
Sbjct: 5510 QEEGDC----CPTFRCRPQL-----------CSYNGTFYGVGATFPGAL-PCHMCTCLSG 5553
Query: 629 N-----VQCLARRCVPLPCP---EPVLLPGECCPQCPAAPAPAGCPRP-GAAHARHQEYF 679
+ VQC C CP E + G+CC +C C P G ++ +
Sbjct: 5554 DTQDPTVQCQEDACNNTTCPQGFEYKRVAGQCCGEC----VQTACLTPDGQPVQLNETWV 5609
Query: 680 SPPGDPCRRCLC-LDGSV---SCQRLPCPPAPCAHP--RQGPCCPSCD 721
+ D C LC +G V + Q CP R+ CC SC+
Sbjct: 5610 NSHVDNCTVYLCEAEGGVHLLTPQPASCPDVSSCRGSLRKTGCCYSCE 5657
Score = 77.0 bits (188), Expect = 6e-14
Identities = 112/406 (27%), Positives = 143/406 (35%), Gaps = 74/406 (18%)
Query: 229 CPPSPCPEPVLRPGHCCPTCQGCTEGGSHWEHGQEWTTPGDPCR-----ICRCLEGHIQ- 282
CPP P + +L C G + D CR C+ LE + +
Sbjct: 5288 CPPQPLCDLML--SQVFAECHNLVPPGPFFN-----ACISDHCRGRLEVPCQSLEAYAEL 5340
Query: 283 CRQRECASLCPYPARPLPGTCCPVCDGCFLNGREHRSGEPVGSGDPCSHCRCANGSVQCE 342
CR R S G +CD L + +P G P + C N S Q E
Sbjct: 5341 CRARGVCS-------DWRGATGGLCD---LTCPPTKVYKPCGPIQPAT-CNSRNQSPQLE 5389
Query: 343 PLP----CPPVPC---RHPGKIPGQCCPVC--DGC-EYQGHQYQSQETFRLQERGLCVRC 392
+ CP H G I Q CP DG ++ G ++ S C C
Sbjct: 5390 GMAEGCFCPEDQILFNAHMG-ICVQACPCVGPDGFPKFPGERWVSN----------CQSC 5438
Query: 393 SCQAGEVSCEEQECPVTPCALPASGRQLCPACELDGEEFAEGVQWEPDGRPCTACVCQDG 452
C G VS + C PC A G+ P C G + E P T CVC
Sbjct: 5439 VCDEGSVSVQ---CKPLPC--DAQGQP--PPCNRPGFVTVTRPRAENPCCPETVCVCNTT 5491
Query: 453 VPKCGAVLCPPAPCQHPTQPPGACCPSC----DSCTYHSQVYANGQNFTDADSPCHACHC 508
+CPP TQ G CCP+ C+Y+ Y G F A PCH C C
Sbjct: 5492 TCPQSLPVCPPGQESICTQEEGDCCPTFRCRPQLCSYNGTFYGVGATFPGA-LPCHMCTC 5550
Query: 509 -----QDGTVTCSLVDCPPTTCARP---QSGPGQCCPRCPD--CILE--EEVFVDGESFS 556
QD TV C C TTC + + GQCC C C+ + V ++ +
Sbjct: 5551 LSGDTQDPTVQCQEDACNNTTCPQGFEYKRVAGQCCGECVQTACLTPDGQPVQLNETWVN 5610
Query: 557 HPRDPCQECRCQ-EGHAHC---QPRPCPR-APCAHPLPGTCCPNDC 597
D C C+ EG H QP CP + C L T C C
Sbjct: 5611 SHVDNCTVYLCEAEGGVHLLTPQPASCPDVSSCRGSLRKTGCCYSC 5656
Score = 70.1 bits (170), Expect = 8e-12
Identities = 98/381 (25%), Positives = 123/381 (32%), Gaps = 95/381 (24%)
Query: 437 WEPDGRPCTACVCQDGVPKCGAVLCPPAPCQH-PTQPPGACCPSCDSCTYHSQVYANGQN 495
W P G P TA P AP PT P P CD SQV+A N
Sbjct: 5264 WAPTGTPPTAS--------------PAAPVSSTPTPTPCPPQPLCDLML--SQVFAECHN 5307
Query: 496 FTDADSPCHAC---HCQDGT-VTCSLVDCPPTTCA--------RPQSGPGQCCPRCPDCI 543
+AC HC+ V C ++ C R +G G C CP
Sbjct: 5308 LVPPGPFFNACISDHCRGRLEVPCQSLEAYAELCRARGVCSDWRGATG-GLCDLTCPPTK 5366
Query: 544 LEEEVFVDGESFSHPRDPCQECRCQEGHAHCQPRP------CPRAPCAHPLPGTCCPNDC 597
+ + P P Q C + Q CP C C
Sbjct: 5367 VYK-----------PCGPIQPATCNSRNQSPQLEGMAEGCFCPEDQILFNAHMGICVQAC 5415
Query: 598 SGCAFGGKEYPSGADFPHPS--DPCRLCRCLSGNVQCLARRCVPLPCPEPVLLPGECCPQ 655
G +P FP C+ C C G+V +C PLPC
Sbjct: 5416 P--CVGPDGFPK---FPGERWVSNCQSCVCDEGSVSV---QCKPLPCD------------ 5455
Query: 656 CPAAPAPAGCPRPGAAHARHQEYFSPPGDPCRRCLCLDGSVSC-QRLP-CPPAP---CAH 710
A P C RPG +P C +C+ + +C Q LP CPP C
Sbjct: 5456 --AQGQPPPCNRPGFVTVTRPRAENPC---CPETVCVCNTTTCPQSLPVCPPGQESICTQ 5510
Query: 711 PRQGPCCPSC----DGCLYQGKEFASGERFPSPTAACHLCLCWEG-----SVSCEPKACA 761
+G CCP+ C Y G + G FP CH+C C G +V C+ AC
Sbjct: 5511 -EEGDCCPTFRCRPQLCSYNGTFYGVGATFPG-ALPCHMCTCLSGDTQDPTVQCQEDACN 5568
Query: 762 PALCP-----FPARGDCCPDC 777
CP G CC +C
Sbjct: 5569 NTTCPQGFEYKRVAGQCCGEC 5589
Score = 67.8 bits (164), Expect = 4e-11
Identities = 81/293 (27%), Positives = 110/293 (37%), Gaps = 64/293 (21%)
Query: 156 CTTCRCLEGTITCNQKPCPRGPCPEPGACCPHCKPGCDYEGQLYEEGVTFLSSSNPCLQ- 214
C +C C EG+++ KP PC G P +PG VT + NPC
Sbjct: 5435 CQSCVCDEGSVSVQCKPL---PCDAQGQPPPCNRPGF--------VTVTRPRAENPCCPE 5483
Query: 215 --CTCLRSRVRCMALKCPPSPCPEPVLRPGHCCPTC----QGCTEGGSHWEHGQEWTTPG 268
C C + CPP G CCPT Q C+ G+ + G T PG
Sbjct: 5484 TVCVCNTTTCPQSLPVCPPGQESICTQEEGDCCPTFRCRPQLCSYNGTFYGVGA--TFPG 5541
Query: 269 D-PCRICRCLEGH-----IQCRQREC-ASLCP--YPARPLPGTCCPVC--DGCFLNGREH 317
PC +C CL G +QC++ C + CP + + + G CC C C
Sbjct: 5542 ALPCHMCTCLSGDTQDPTVQCQEDACNNTTCPQGFEYKRVAGQCCGECVQTACLT----- 5596
Query: 318 RSGEPV--------GSGDPCSHCRC-ANGSVQC---EPLPCPPV-PCRHPGKIPGQCCPV 364
G+PV D C+ C A G V +P CP V CR + G CC
Sbjct: 5597 PDGQPVQLNETWVNSHVDNCTVYLCEAEGGVHLLTPQPASCPDVSSCRGSLRKTG-CCYS 5655
Query: 365 C--DGCE---------YQGHQYQSQETFRLQERGLCVRCSCQAGEVSCEEQEC 406
C D C+ +QG + + TF G C S + E + +C
Sbjct: 5656 CEEDSCQVRINTTILWHQGCETEVNITFC---EGSCPGASKYSAEAQAMQHQC 5705
Score = 47.8 bits (112), Expect = 4e-05
Identities = 46/156 (29%), Positives = 62/156 (39%), Gaps = 29/156 (18%)
Query: 118 VCQDGAAHCGPQAHLPHCRG--CSQNGQTYGNGETFSPDA--CTTCRCLEG-----TITC 168
+C C P CR CS NG YG G TF P A C C CL G T+ C
Sbjct: 5507 ICTQEEGDCCPTFR---CRPQLCSYNGTFYGVGATF-PGALPCHMCTCLSGDTQDPTVQC 5562
Query: 169 NQKPCPRGPCPE-------PGACCPHC-KPGC-DYEGQLYEEGVTFLSSS-NPCLQCTCL 218
+ C CP+ G CC C + C +GQ + T+++S + C C
Sbjct: 5563 QEDACNNTTCPQGFEYKRVAGQCCGECVQTACLTPDGQPVQLNETWVNSHVDNCTVYLC- 5621
Query: 219 RSRVRCMALKCPPSPCPE-----PVLRPGHCCPTCQ 249
+ L P+ CP+ LR CC +C+
Sbjct: 5622 EAEGGVHLLTPQPASCPDVSSCRGSLRKTGCCYSCE 5657
Score = 43.5 bits (101), Expect = 8e-04
Identities = 49/203 (24%), Positives = 62/203 (30%), Gaps = 53/203 (26%)
Query: 172 PCPRGPCPEPGACCPHCKPGCDY-EGQLYEEGVTFLSSSNPCLQCTCLRSRVRCMALKCP 230
P P G C + C G + E + +L++ C Q C +CP
Sbjct: 249 PLPAGNCTDEEGICHRTLLGPAFAECHALVDSTAYLAA---CAQDLC----------RCP 295
Query: 231 PSPCPEPVLRPGHCCPTCQGCTEGGSHWEHGQEWTTPGDPCRICRCLEGHIQCRQRECAS 290
PC V C GG + W P R C H +C C
Sbjct: 296 TCPCATFVEYSRQCAHA------GGQP----RNWRCPELCPRTCPLNMQHQECGS-PCTD 344
Query: 291 LCPYPARPL-------------PGTCCPVCDG-------------CFLNGREHRSGEPVG 324
C P R PG C V D C GR + G
Sbjct: 345 TCSNPQRAQLCEDHCVDGCFCPPGRSCTVLDDITHSGCLPLGQCPCTHGGRTYSPGTSFN 404
Query: 325 SGDPCSHCRCANGSVQCEPLPCP 347
+ CS C C+ G QC+ LPCP
Sbjct: 405 T--TCSSCTCSGGLWQCQDLPCP 425
Score = 42.4 bits (98), Expect = 0.002
Identities = 38/162 (23%), Positives = 58/162 (35%), Gaps = 28/162 (17%)
Query: 362 CPVCDGCEYQGHQYQSQETFRLQERGLCVRCSCQAGEVSCEEQECPVTPCALPASGRQLC 421
CP C + + Q C + ++ + QEC +PC S Q
Sbjct: 294 CPTCPCATFVEYSRQCAHAGGQPRNWRCPELCPRTCPLNMQHQECG-SPCTDTCSNPQRA 352
Query: 422 PACELDGEEFAEGVQWEPDGRPCTACVCQDGVPKCGAVLCPPAPCQHPTQPPGACCPSCD 481
CE + +G + P GR CT D + G + P G C
Sbjct: 353 QLCE---DHCVDGC-FCPPGRSCTVL---DDITHSGCL------------PLGQC----- 388
Query: 482 SCTYHSQVYANGQNFTDADSPCHACHCQDGTVTCSLVDCPPT 523
CT+ + Y+ G +F ++ C +C C G C + CP T
Sbjct: 389 PCTHGGRTYSPGTSF---NTTCSSCTCSGGLWQCQDLPCPGT 427
Score = 40.4 bits (93), Expect = 0.007
Identities = 23/69 (33%), Positives = 30/69 (43%), Gaps = 8/69 (11%)
Query: 116 ACVCQDGAAHCG--PQAHLPHCRGCSQNGQTYGNGETFSPDACTTCRCLEGTITCNQKPC 173
+C D H G P P C+ G+TY G +F+ C++C C G C PC
Sbjct: 370 SCTVLDDITHSGCLPLGQCP----CTHGGRTYSPGTSFNT-TCSSCTCSGGLWQCQDLPC 424
Query: 174 PRGPCPEPG 182
P G C G
Sbjct: 425 P-GTCSVQG 432
Score = 39.7 bits (91), Expect = 0.011
Identities = 120/541 (22%), Positives = 176/541 (32%), Gaps = 110/541 (20%)
Query: 97 WGLGRAWPEGARWEPDACTACVCQDGAAH--CGPQAHLPHCRGCSQNGQTYGNGETFSPD 154
W L + P+ A D CTA + A C H P C + E D
Sbjct: 1058 WKLSPSCPD-ALAPKDPCTANPFRKSWAQKQCSI-LHGPTFAACRSQVDSTKYYEACVND 1115
Query: 155 ACTT-----CRCLEGTITCNQKPC-PRGPCPE---PGAC---CPHCKP--GCDYEGQLYE 200
AC C C + + C G C P C C P GC++ Q
Sbjct: 1116 ACACDSGGDCECFCTAVAAYAQACHDAGLCVSWRTPDTCPLFCDFYNPHGGCEWHYQ--- 1172
Query: 201 EGVTFLSSSNPCLQCTCLRSRVRCMA---------LKCPPSPCPEPVLRPGH--CCPTCQ 249
PCL+ TC C+ KCPPS +P C C
Sbjct: 1173 ------PCGAPCLK-TCRNPSGHCLVDLPGLEGCYPKCPPS---QPFFNEDQMKCVAQCG 1222
Query: 250 GCTEGGSHWEHGQEWTTPGDPCRICRCLEGHIQCRQRECASLCPYPARPLPGTCCPVCDG 309
+ G++++ G T + C+ C C IQC A C Y R
Sbjct: 1223 CYDKDGNYYDVGARVPT-AENCQSCNCTPSGIQCAHSLEACTCTYEDRTYS--------- 1272
Query: 310 CFLNGREHRSGEPVGSGDPCSHCRC-ANGSVQCEPLPCPPVPCRHP-------------- 354
+ + + +G+ C C +NG++ + + CP P P
Sbjct: 1273 --YQDVIYNTTDGLGA---CLIAICGSNGTIIRKAVACPGTPATTPFTFTTAWVPHSTTS 1327
Query: 355 GKIPGQCCPVCDGCE----YQGHQYQSQ------ETFR-LQERGLCVRCSCQAGEVSCEE 403
+P V + C Y GH+ + ETF L++RG V C A ++ C
Sbjct: 1328 PALPVSTVCVREVCRWSSWYNGHRPEPGLGGGDFETFENLRQRGYQV-CPVLA-DIECRA 1385
Query: 404 QECPVTPCALPASGRQLCPACE-LDGEEFAEGVQWEPDGRPCTACVCQD---GVPKCGAV 459
+ P P L G+Q+ C+ + G A Q P +C D V C V
Sbjct: 1386 AQLPDMP--LEELGQQV--DCDRMRGLMCANSQQSPP--------LCHDYELRVLCCEYV 1433
Query: 460 LCPPAPCQHPTQPPGACCPSCDSCTYHSQVYANGQN---FTDADSPCHACHCQDGTVTCS 516
C P+P + P + + +Q A + T + A Q G+ +
Sbjct: 1434 PCGPSPAPGTSPQPSLSASTEPAVPTPTQTTATEKTTLWVTPSIRSTAALTSQTGSSS-- 1491
Query: 517 LVDCPPTTCARPQSGPGQCCPRCPDCILEEEVFVDGESFSHPRDPCQECRCQEGHAHCQP 576
P T G C PRC +E + E + + R GH QP
Sbjct: 1492 ----GPVTVTPSAPGTTTCQPRCQWTEWFDEDYPKSEQLGGDVESYDKIRAAGGHLCQQP 1547
Query: 577 R 577
+
Sbjct: 1548 K 1548
Score = 38.1 bits (87), Expect = 0.033
Identities = 56/214 (26%), Positives = 69/214 (32%), Gaps = 46/214 (21%)
Query: 495 NFTDADSPCHACHCQDGTVTC-SLVDCPPTTCARPQSGPGQC-CPRCPDCILEEEVFVDG 552
N TD + CH C +LVD A Q C CP CP E
Sbjct: 254 NCTDEEGICHRTLLGPAFAECHALVDSTAYLAACAQD---LCRCPTCPCATFVEYSRQCA 310
Query: 553 ESFSHPRDPCQECRCQEGHAHCQPRPCPRAPCAHPLPGTCCPNDCSGCAFGGKEYPSGAD 612
+ PR+ RC E PR CP H G+ C + CS
Sbjct: 311 HAGGQPRN----WRCPE----LCPRTCP-LNMQHQECGSPCTDTCSN------------- 348
Query: 613 FPHPSDPCRLCRCLSGNVQCLARRCVPLPCPEPVLLPGECCP--QCPAAPAPAGCPRPGA 670
P + C C+ G R C L + + G C P QCP C G
Sbjct: 349 -PQRAQLCE-DHCVDGCFCPPGRSCTVL---DDITHSG-CLPLGQCP-------CTHGGR 395
Query: 671 AHARHQEYFSPPGDPCRRCLCLDGSVSCQRLPCP 704
++ + C C C G CQ LPCP
Sbjct: 396 TYSPGTSF----NTTCSSCTCSGGLWQCQDLPCP 425
Score = 35.8 bits (81), Expect = 0.16
Identities = 38/155 (24%), Positives = 45/155 (29%), Gaps = 44/155 (28%)
Query: 636 RCVPLPCPEPVLLPGECCP---QCPAAPAPAGCPRPGAAHARHQEYFSPPGDPC------ 686
RC PC V +C Q P CPR + +HQE SP D C
Sbjct: 293 RCPTCPCATFVEYSRQCAHAGGQPRNWRCPELCPRTCPLNMQHQECGSPCTDTCSNPQRA 352
Query: 687 ----------------RRCLCLDGSVSCQRLPCPPAPCAHPRQGPCCPSCDGCLYQGKEF 730
R C LD LP PC H G+ +
Sbjct: 353 QLCEDHCVDGCFCPPGRSCTVLDDITHSGCLPLGQCPCTH---------------GGRTY 397
Query: 731 ASGERFPSPTAACHLCLCWEGSVSCEPKACAPALC 765
+ G F C C C G C+ C P C
Sbjct: 398 SPGTSF---NTTCSSCTCSGGLWQCQDLPC-PGTC 428
Score = 34.7 bits (78), Expect = 0.37
Identities = 41/144 (28%), Positives = 49/144 (34%), Gaps = 16/144 (11%)
Query: 156 CTTCRCLEGTITCNQKPCPR-GPCPEPGACCPHCKPGCDYEGQLYEEGVTFLSS-SNPCL 213
C TC C T + C G P C C C Q E G + SNP
Sbjct: 294 CPTCPC--ATFVEYSRQCAHAGGQPRNWRCPELCPRTCPLNMQHQECGSPCTDTCSNPQR 351
Query: 214 QCTCLRSRVRCM-ALKCPPS-PCP--EPVLRPGHCCPTCQ-GCTEGGSHWEHGQEWTTPG 268
C C+ CPP C + + G C P Q CT GG + G + T
Sbjct: 352 AQLC---EDHCVDGCFCPPGRSCTVLDDITHSG-CLPLGQCPCTHGGRTYSPGTSFNTT- 406
Query: 269 DPCRICRCLEGHIQCRQRECASLC 292
C C C G QC+ C C
Sbjct: 407 --CSSCTCSGGLWQCQDLPCPGTC 428
Score = 33.5 bits (75), Expect = 0.81
Identities = 49/208 (23%), Positives = 61/208 (29%), Gaps = 47/208 (22%)
Query: 117 CVCQDG-----AAHCGPQAHLPHCRGCSQNGQTYGNGETFSPDACTTCRCLEGTITCNQK 171
C C G A C P P C +G GE D C C G ++C
Sbjct: 735 CTCPAGTFLNDAGACVPAQECP----CYAHGTVLAPGEVVH-DEGAVCSCTGGKLSCLGA 789
Query: 172 PCPRGPCPEPGACCPHCKPGCDYEGQLYEEGVTFLSSSNPCLQC--TCLRSRVRCMALKC 229
+ G P C S+ P +C +C V C + C
Sbjct: 790 SLQKST----GCAAPMVYLDCSNS-----------SAGTPGAECLRSCHTLDVGCFSTHC 834
Query: 230 PPSPCPEPVLRPGHCCPTCQGC-TEGGSHWEHGQEWTTPGDP----CRICRCLEGHIQCR 284
S C P PG GC E H + PG+ C C C +C
Sbjct: 835 V-SGCVCP---PGLVSDGSGGCIAEEDCPCVHNEATYKPGETIRVDCNTCTCRNRRWECS 890
Query: 285 QRECASLCPYPARPLPGTCCPVCDGCFL 312
R C GTC DG F+
Sbjct: 891 HRLCL-----------GTCVAYGDGHFI 907
Score = 30.8 bits (68), Expect = 5.3
Identities = 73/325 (22%), Positives = 97/325 (29%), Gaps = 93/325 (28%)
Query: 215 CTCLRSR-VRCMALKCPPSPCPEPVL-----RPGHCCPTCQGCTEGGSHWEHGQEWTTPG 268
C C RS C AL C + R G C Q C + Q +
Sbjct: 656 CNCERSEDCLCAALSSYVHACAAKGVQLSDWRDGVCTKYMQNCPKS-------QRYAYVV 708
Query: 269 DPCR-ICRCLEGHIQCRQRECASLCPYPARPLPGTCCPVCDGCFLNGREHRSGEPVGSGD 327
D C+ CR L E C P+ G CP G FLN G+
Sbjct: 709 DACQPTCRGLS--------EADVTCSVSFVPVDGCTCPA--GTFLND--------AGACV 750
Query: 328 PCSHCRC-ANGSVQCEPLPCPPVPCRHPGKIPGQCCPVCDGCEYQGHQYQSQETFRLQER 386
P C C A+G+V PG++ + +
Sbjct: 751 PAQECPCYAHGTVLA------------PGEV-------------------------VHDE 773
Query: 387 GLCVRCSCQAGEVSCEEQECPVTPCALPASGRQLCPACELDGEEFAEGVQWEPDGRPC-- 444
G CSC G++SC +L S P LD + G R C
Sbjct: 774 GAV--CSCTGGKLSC-------LGASLQKSTGCAAPMVYLDCSNSSAGTPGAECLRSCHT 824
Query: 445 --TACVCQDGVPKCGAVLCPPAPCQHPTQPPGACCPSCD-SCTYHSQVYANGQNFTDADS 501
C V C +CPP + G C D C ++ Y G+
Sbjct: 825 LDVGCFSTHCVSGC---VCPPGLV---SDGSGGCIAEEDCPCVHNEATYKPGETIR---V 875
Query: 502 PCHACHCQDGTVTCSLVDCPPTTCA 526
C+ C C++ CS C T A
Sbjct: 876 DCNTCTCRNRRWECSHRLCLGTCVA 900
Score = 30.4 bits (67), Expect = 6.9
Identities = 48/200 (24%), Positives = 64/200 (32%), Gaps = 27/200 (13%)
Query: 454 PKCGAVLCPPAPCQHPTQPPGACCPSCDSCTY-HSQVYANGQNFTDADS---PC--HACH 507
P C L P PC T P + C+ H +A ++ D+ C AC
Sbjct: 1062 PSCPDALAPKDPC---TANPFRKSWAQKQCSILHGPTFAACRSQVDSTKYYEACVNDACA 1118
Query: 508 CQDGTVTCSLVDCPPTTCARPQSGPGQCCP-RCPD-CILEEEVFVDGESFSHPRDPC--- 562
C G C A+ G C R PD C L + + PC
Sbjct: 1119 CDSGG-DCECFCTAVAAYAQACHDAGLCVSWRTPDTCPLFCDFYNPHGGCEWHYQPCGAP 1177
Query: 563 --QECRCQEGHA--------HCQPRPCPRAPCAHPLPGTCCPNDCSGCAFGGKEYPSGAD 612
+ CR GH C P+ CP + C C G Y GA
Sbjct: 1178 CLKTCRNPSGHCLVDLPGLEGCYPK-CPPSQPFFNEDQMKCVAQCGCYDKDGNYYDVGAR 1236
Query: 613 FPHPSDPCRLCRCLSGNVQC 632
P ++ C+ C C +QC
Sbjct: 1237 VP-TAENCQSCNCTPSGIQC 1255
>gi|89191868 von Willebrand factor preproprotein [Homo sapiens]
Length = 2813
Score = 79.7 bits (195), Expect = 1e-14
Identities = 139/560 (24%), Positives = 178/560 (31%), Gaps = 160/560 (28%)
Query: 84 LESCECHPASPQCWGLGRAWPEGARWEPDACTACVCQDGAAHCGPQAHLPHCRGCSQNGQ 143
+ SC HP+ + EG+ +ACT C+ +DG H +A +P
Sbjct: 2224 VSSCGDHPSEGCFCPPDKVMLEGSCVPEEACTQCIGEDGVQHQFLEAWVP---------- 2273
Query: 144 TYGNGETFSPDACTTCRCLEG-TITCNQKPCPRGPCPEPG------------ACCPH--- 187
C C CL G + C +PCP P G CCP
Sbjct: 2274 --------DHQPCQICTCLSGRKVNCTTQPCPTAKAPTCGLCEVARLRQNADQCCPEYEC 2325
Query: 188 -CKP-GCDYEGQLY-EEG----VTFLSSSNPCLQCTCLRSRVRCMALKCPPSPCPE---P 237
C P CD + E G +T P C C + + ++ PPS CP P
Sbjct: 2326 VCDPVSCDLPPVPHCERGLQPTLTNPGECRPNFTCACRKEECKRVS---PPS-CPPHRLP 2381
Query: 238 VLRPGHCCPTCQGCTEGGSHWEHGQEWTTPGDPCRICRCLEGHIQCRQRECASLCPYPAR 297
LR CC + C C C+ + C AS
Sbjct: 2382 TLRKTQCCDEYE-CA---------------------CNCVNSTVSCPLGYLASTATNDCG 2419
Query: 298 PLPGTCCP--VCDGCFLNGREHRSG-EPVGS--GDPCSHCRCANGS--------VQCEPL 344
TC P VC HRS PVG + C C C + QC
Sbjct: 2420 CTTTTCLPDKVC--------VHRSTIYPVGQFWEEGCDVCTCTDMEDAVMGLRVAQCSQK 2471
Query: 345 PCPPVPCR-------HPGKIPGQCCPVCDGCEY---------------QGHQYQSQETFR 382
PC CR H G+ G+C P CE G Q+ S E
Sbjct: 2472 PCED-SCRSGFTYVLHEGECCGRCLP--SACEVVTGSPRGDSQSSWKSVGSQWASPENPC 2528
Query: 383 LQERGLCVRCS----CQAGEVSCEEQECPVTPCALPASGR--QLCP--------ACELDG 428
L CVR Q VSC + E PV P S + CP AC L+G
Sbjct: 2529 LINE--CVRVKEEVFIQQRNVSCPQLEVPVCPSGFQLSCKTSACCPSCRCERMEACMLNG 2586
Query: 429 EEFAEGVQWEPDGRPCTACVC--QDGV-----PKCGAVLCPPAPCQHPTQ-PPGACCPSC 480
G D CT C C Q GV +C C P P + + G CC C
Sbjct: 2587 TVIGPGKTVMID--VCTTCRCMVQVGVISGFKLECRKTTCNPCPLGYKEENNTGECCGRC 2644
Query: 481 --DSCTYH---SQVYANGQNFTDADS-PCHACHCQDGTV---TCSLVDCPP-------TT 524
+CT Q+ ++ T D H C + + CPP
Sbjct: 2645 LPTACTIQLRGGQIMTLKRDETLQDGCDTHFCKVNERGEYFWEKRVTGCPPFDEHKCLAE 2704
Query: 525 CARPQSGPGQCCPRC--PDC 542
+ PG CC C P+C
Sbjct: 2705 GGKIMKIPGTCCDTCEEPEC 2724
Score = 72.8 bits (177), Expect = 1e-12
Identities = 142/647 (21%), Positives = 195/647 (30%), Gaps = 181/647 (27%)
Query: 224 CMALKCPPSPCPEPVLRPGHCCPTCQGCTEGGSHWEHGQEWTTPGDPCRIC-------RC 276
C C E + H C T C + W TP C C
Sbjct: 2163 CQQDSCHQEQVCEVIASYAHLCRTNGVCVD----------WRTPDFCAMSCPPSLVYNHC 2212
Query: 277 LEG---HIQCRQRECAS------LCPYPARPLPGTCCP--VCDGCF-LNGREHRSGEP-V 323
G H C CP L G+C P C C +G +H+ E V
Sbjct: 2213 EHGCPRHCDGNVSSCGDHPSEGCFCPPDKVMLEGSCVPEEACTQCIGEDGVQHQFLEAWV 2272
Query: 324 GSGDPCSHCRCANG-SVQCEPLPCPPVPCRHPGKIPGQCCPVCDGCEYQGHQYQSQETFR 382
PC C C +G V C PCP P C CE + + +
Sbjct: 2273 PDHQPCQICTCLSGRKVNCTTQPCPTAKA-----------PTCGLCEVARLRQNADQC-- 2319
Query: 383 LQERGLCVRCSCQAGEVSCEEQECPVTPCALPASGRQLCPACELDGEEFAEGVQWEPDGR 442
C E C+ C + P +P R L P GE R
Sbjct: 2320 -----------CPEYECVCDPVSCDLPP--VPHCERGLQPTLTNPGE-----------CR 2355
Query: 443 PCTACVCQDGVPKCGAVLCPPAPCQH-PTQPPGACCPSCDSCTYHSQVYANGQNFTDADS 501
P C C+ +C V P P PT CC +
Sbjct: 2356 PNFTCACRK--EECKRVSPPSCPPHRLPTLRKTQCCDEYEC------------------- 2394
Query: 502 PCHACHCQDGTVTCSL----------VDCPPTTCARPQSGPGQCCPRCPD--CILEEEVF 549
AC+C + TV+C L C TTC PD C+ ++
Sbjct: 2395 ---ACNCVNSTVSCPLGYLASTATNDCGCTTTTCL-------------PDKVCVHRSTIY 2438
Query: 550 VDGESFSHPRDPCQECRCQEGH--------AHCQPRPCP---RAPCAHPLP-----GTCC 593
G+ + + C C C + A C +PC R+ + L G C
Sbjct: 2439 PVGQFWE---EGCDVCTCTDMEDAVMGLRVAQCSQKPCEDSCRSGFTYVLHEGECCGRCL 2495
Query: 594 PNDC---SGCAFGGKEYP---SGADFPHPSDPCRLCRCLSGNVQC-LARRCVPLP----- 641
P+ C +G G + G+ + P +PC + C+ + + +R V P
Sbjct: 2496 PSACEVVTGSPRGDSQSSWKSVGSQWASPENPCLINECVRVKEEVFIQQRNVSCPQLEVP 2555
Query: 642 -CPEPVLLP---GECCPQCPAAPAPAGCPRPGAAHARHQEYFSPPGDPCRRCLCLDGSVS 697
CP L CCP C A C G + CR C+ G +S
Sbjct: 2556 VCPSGFQLSCKTSACCPSCRCERMEA-CMLNGTVIGPGKTVMIDVCTTCR-CMVQVGVIS 2613
Query: 698 -----CQRLPCPPAPCAHPRQ---GPCCPSC--DGCLYQ--GKEFASGERFPSPTAACHL 745
C++ C P P + + G CC C C Q G + + +R + C
Sbjct: 2614 GFKLECRKTTCNPCPLGYKEENNTGECCGRCLPTACTIQLRGGQIMTLKRDETLQDGCDT 2673
Query: 746 CLC---------WEGSVS-CEP----KACAPALCPFPARGDCCPDCD 778
C WE V+ C P K A G CC C+
Sbjct: 2674 HFCKVNERGEYFWEKRVTGCPPFDEHKCLAEGGKIMKIPGTCCDTCE 2720
Score = 49.7 bits (117), Expect = 1e-05
Identities = 63/275 (22%), Positives = 91/275 (33%), Gaps = 44/275 (16%)
Query: 506 CHCQDGT-VTCSLVDCPPTTCAR-----PQSGPGQCCPRCPDCILEEEVFVDG------- 552
C C DG C + CA PG+C CP + +V++
Sbjct: 613 CSCSDGRECLCGALASYAAACAGRGVRVAWREPGRCELNCP----KGQVYLQCGTPCNLT 668
Query: 553 -ESFSHPRDPCQECRCQEGHAHCQPRPCPRAPCAHPLPGTCCPNDCSGCAFGGKEYPSGA 611
S S+P + C E C EG C P G C P C + G+ +
Sbjct: 669 CRSLSYPDEECNEA-CLEG-CFCPPG------LYMDERGDCVPKAQCPCYYDGEIFQPED 720
Query: 612 DFPHPSDPCRLCRCLSGNVQCLARRCVPLPCPEPVLLPGECCPQCPAAPAPAGCPRPGAA 671
F SD +C C G + C P+ VL P + C P
Sbjct: 721 IF---SDHHTMCYCEDGFMHCTMSGVPGSLLPDAVL----SSPLSHRSKRSLSCRPPMVK 773
Query: 672 HARHQEYFSPPGDPCRRCLCLDGSVSCQRLPC------PPAPCAHPRQGPCCPSCDGCLY 725
+ G C + C + + C + C PP H + C C +
Sbjct: 774 LVCPADNLRAEGLECTKT-CQNYDLECMSMGCVSGCLCPPGMVRHENRCVALERCP-CFH 831
Query: 726 QGKEFASGERFPSPTAACHLCLCWEGSVSCEPKAC 760
QGKE+A GE + C+ C+C + +C C
Sbjct: 832 QGKEYAPGE---TVKIGCNTCVCRDRKWNCTDHVC 863
Score = 46.6 bits (109), Expect = 9e-05
Identities = 69/265 (26%), Positives = 91/265 (34%), Gaps = 54/265 (20%)
Query: 98 GLGRAWPEGARWEPDACTACVCQDGAAH--CGPQAHLPHCRGCSQNGQTYGNGETFSPDA 155
G+ AW E R E + C G + CG +L CR S PD
Sbjct: 637 GVRVAWREPGRCELN------CPKGQVYLQCGTPCNLT-CRSLSY------------PDE 677
Query: 156 CTTCRCLEGTITCNQKPCPRGP-CPEPGACCPHCKPGCDYEGQLYEEGVTFLSSSNPCLQ 214
CLEG CP G E G C P + C Y+G++++ F S+
Sbjct: 678 ECNEACLEGCF------CPPGLYMDERGDCVPKAQCPCYYDGEIFQPEDIF---SDHHTM 728
Query: 215 CTCLRSRVRCMALKCPPSPCPEPVLRPGHCCPTCQGCTEGGSHWEHGQEWTTPGDPCRI- 273
C C + C P S P+ VL P S + P D R
Sbjct: 729 CYCEDGFMHCTMSGVPGSLLPDAVL----SSPLSHRSKRSLSCRPPMVKLVCPADNLRAE 784
Query: 274 ---C--RCLEGHIQCRQRECAS--LCP-----YPARPLPGTCCPVCDGCFLNGREHRSGE 321
C C ++C C S LCP + R + CP CF G+E+ GE
Sbjct: 785 GLECTKTCQNYDLECMSMGCVSGCLCPPGMVRHENRCVALERCP----CFHQGKEYAPGE 840
Query: 322 PVGSGDPCSHCRCANGSVQCEPLPC 346
V G C+ C C + C C
Sbjct: 841 TVKIG--CNTCVCRDRKWNCTDHVC 863
Score = 43.5 bits (101), Expect = 8e-04
Identities = 37/137 (27%), Positives = 49/137 (35%), Gaps = 25/137 (18%)
Query: 115 TACVCQDGAAHCGPQAHLPHCRGCSQNGQT-YG--NGETFSP-------------DACTT 158
T C C G C A L + R C+Q G YG + SP T
Sbjct: 253 TLCECA-GGLECACPALLEYARTCAQEGMVLYGWTDHSACSPVCPAGMEYRQCVSPCART 311
Query: 159 CRCLEGTITCNQK-----PCPRGPCPEPGACCPHCKPGCDYEGQLYEEGVTFLSSSNPCL 213
C+ L C ++ CP G + G C + C + G+ Y G S S C
Sbjct: 312 CQSLHINEMCQERCVDGCSCPEGQLLDEGLCVESTECPCVHSGKRYPPGT---SLSRDCN 368
Query: 214 QCTCLRSRVRCMALKCP 230
C C S+ C +CP
Sbjct: 369 TCICRNSQWICSNEECP 385
Score = 40.4 bits (93), Expect = 0.007
Identities = 78/375 (20%), Positives = 113/375 (30%), Gaps = 102/375 (27%)
Query: 104 PEGARWEPDACTACVCQDGAAHCGPQAHLPHCRGCSQNGQTYGNGETFSPDACTTCRCLE 163
P R+ +AC A + LP+ R C + + +G CL
Sbjct: 574 PRMTRFSEEACAVLTSPTFEACHRAVSPLPYLRNCRYDVCSCSDGR----------ECLC 623
Query: 164 GTITCNQKPCP----RGPCPEPGACCPHCKPGCDYEGQLYEEGVTFLSSSNPCLQCTCLR 219
G + C R EPG C +C +GQ+Y L PC
Sbjct: 624 GALASYAAACAGRGVRVAWREPGRCELNCP-----KGQVY------LQCGTPC------- 665
Query: 220 SRVRCMALKCPPSPCPEPVLRP------------GHCCPTCQ-GCTEGGSHWEHGQEWTT 266
+ C +L P C E L G C P Q C G ++ ++
Sbjct: 666 -NLTCRSLSYPDEECNEACLEGCFCPPGLYMDERGDCVPKAQCPCYYDGEIFQPEDIFS- 723
Query: 267 PGDPCRICRCLEGHIQCRQRECASLCPYPARPLPGTCCPVCDGCFLNGREHRSGEPVGSG 326
D +C C +G + C +PG+ P D + HRS +
Sbjct: 724 --DHHTMCYCEDGFMHCTMSG-----------VPGSLLP--DAVLSSPLSHRSKRSLSCR 768
Query: 327 DPCSHCRCANGSVQCEPLPCPPVPCRHPGKIPGQCCPVCDGCEYQGHQYQSQETFRLQER 386
P C +++ E L +C C + +
Sbjct: 769 PPMVKLVCPADNLRAEGL---------------ECTKTCQNYDLE-----------CMSM 802
Query: 387 GLCVRCSCQAGEVSCEEQECPVTPCALPASGRQLCPACELDGEEFAEGVQWEPDGRPCTA 446
G C C G V E C + CP C G+E+A G E C
Sbjct: 803 GCVSGCLCPPGMVR-HENRCVAL---------ERCP-CFHQGKEYAPG---ETVKIGCNT 848
Query: 447 CVCQDGVPKCGAVLC 461
CVC+D C +C
Sbjct: 849 CVCRDRKWNCTDHVC 863
Score = 38.9 bits (89), Expect = 0.019
Identities = 35/132 (26%), Positives = 48/132 (36%), Gaps = 43/132 (32%)
Query: 562 CQECRCQEGHAHCQPR-----PCPRAPCAHPLPGTC---C-------------------- 593
C+E +E C+ R P + C HP P C C
Sbjct: 1130 CEERNLRENGYECEWRYNSCAPACQVTCQHPEPLACPVQCVEGCHAHCPPGKILDELLQT 1189
Query: 594 ---PNDCSGCAFGGKEYPSGADFP-HPSDP--CRLCRCLSGNVQCLARRCVPLPCPEP-- 645
P DC C G+ + SG +PSDP C++C C N+ C A C EP
Sbjct: 1190 CVDPEDCPVCEVAGRRFASGKKVTLNPSDPEHCQICHCDVVNLTCEA-------CQEPGG 1242
Query: 646 VLLPGECCPQCP 657
+++P P P
Sbjct: 1243 LVVPPTDAPVSP 1254
Score = 38.1 bits (87), Expect = 0.033
Identities = 28/101 (27%), Positives = 38/101 (37%), Gaps = 15/101 (14%)
Query: 608 PSGADFPHPSDPC-RLCRCLSGNVQCLARRCVPLPCPEPVLLPGECC---PQCPAAPAPA 663
P+G ++ PC R C+ L N C R CPE LL C +CP +
Sbjct: 296 PAGMEYRQCVSPCARTCQSLHINEMCQERCVDGCSCPEGQLLDEGLCVESTECPCVHSGK 355
Query: 664 GCPRPGAAHARHQEYFSPPGDPCRRCLCLDGSVSCQRLPCP 704
P PG + +R C C+C + C CP
Sbjct: 356 RYP-PGTSLSR----------DCNTCICRNSQWICSNEECP 385
Score = 37.4 bits (85), Expect = 0.056
Identities = 35/140 (25%), Positives = 45/140 (32%), Gaps = 20/140 (14%)
Query: 159 CRC---LEGTITCNQKPCPRGPCPEPGACCPHCKPGCDYEGQLYEEGVTFLSSSNPCLQ- 214
C C LE TC Q+ + AC P C G +Y +PC +
Sbjct: 263 CACPALLEYARTCAQEGMVLYGWTDHSACSPVCPAGMEYR-----------QCVSPCART 311
Query: 215 CTCLRSRVRCMALKCPPSPCPE-PVLRPGHCCPTCQ-GCTEGGSHWEHGQEWTTPGDPCR 272
C L C CPE +L G C + + C G + G T+ C
Sbjct: 312 CQSLHINEMCQERCVDGCSCPEGQLLDEGLCVESTECPCVHSGKRYPPG---TSLSRDCN 368
Query: 273 ICRCLEGHIQCRQRECASLC 292
C C C EC C
Sbjct: 369 TCICRNSQWICSNEECPGEC 388
Score = 35.8 bits (81), Expect = 0.16
Identities = 42/183 (22%), Positives = 58/183 (31%), Gaps = 46/183 (25%)
Query: 112 DACTACVCQDGAAHCGPQAHLPHCRGCSQNGQTYG-NGETFSPDACTTCRCLEGTITCNQ 170
D C+ D A C A H C+Q+G+ T P +C E C
Sbjct: 1087 DTCSCESIGDCACFCDTIAAYAHV--CAQHGKVVTWRTATLCPQSCEERNLRENGYECEW 1144
Query: 171 K-----PCPRGPC--PEPGACCPHCKPGCDYEGQLYEEGVTFLSSSNPCLQCTCLRSRVR 223
+ P + C PEP AC C GC
Sbjct: 1145 RYNSCAPACQVTCQHPEPLACPVQCVEGCH------------------------------ 1174
Query: 224 CMALKCPPSPCPEPVLRPGHCCPTCQGCTEGGSHWEHGQEWT-TPGDP--CRICRCLEGH 280
CPP + +L+ C C G + G++ T P DP C+IC C +
Sbjct: 1175 ---AHCPPGKILDELLQTCVDPEDCPVCEVAGRRFASGKKVTLNPSDPEHCQICHCDVVN 1231
Query: 281 IQC 283
+ C
Sbjct: 1232 LTC 1234
Score = 34.7 bits (78), Expect = 0.37
Identities = 36/149 (24%), Positives = 50/149 (33%), Gaps = 36/149 (24%)
Query: 332 CRCANGSVQCEPLPCPPV-----PCRHPGKI------PGQCCPVCD-GCEYQ------GH 373
C CA G ++C CP + C G + C PVC G EY+
Sbjct: 255 CECAGG-LECA---CPALLEYARTCAQEGMVLYGWTDHSACSPVCPAGMEYRQCVSPCAR 310
Query: 374 QYQSQETFRLQERGLCVRCSCQAGEVSCEEQECPVTPCALPASGRQLCPACELDGEEFAE 433
QS + + CSC G++ E T C SG++ P L
Sbjct: 311 TCQSLHINEMCQERCVDGCSCPEGQLLDEGLCVESTECPCVHSGKRYPPGTSLS------ 364
Query: 434 GVQWEPDGRPCTACVCQDGVPKCGAVLCP 462
R C C+C++ C CP
Sbjct: 365 --------RDCNTCICRNSQWICSNEECP 385
Score = 33.9 bits (76), Expect = 0.62
Identities = 27/96 (28%), Positives = 32/96 (33%), Gaps = 23/96 (23%)
Query: 557 HPRDPCQECRCQEGHAHCQPRPCPRAPCAHPLPGTCCPNDCSGCAFGGKEYPSGADFPHP 616
H + CQE RC +G + CP G C + C GK YP G
Sbjct: 316 HINEMCQE-RCVDGCS------CPEGQLLDE--GLCVESTECPCVHSGKRYPPGTSL--- 363
Query: 617 SDPCRLCRCLSGNVQCLARRCVPLPCPEPVLLPGEC 652
S C C C + C C PGEC
Sbjct: 364 SRDCNTCICRNSQWICSNEEC-----------PGEC 388
Score = 33.1 bits (74), Expect = 1.1
Identities = 30/112 (26%), Positives = 40/112 (35%), Gaps = 25/112 (22%)
Query: 244 CCPTCQGCTEGGSHWEHGQEWTTPGDPC-RICRCLEGHIQCRQRECASLCPYPARPL--P 300
C P C G E+ PC R C+ L + C++R C C P L
Sbjct: 291 CSPVCPA----------GMEYRQCVSPCARTCQSLHINEMCQER-CVDGCSCPEGQLLDE 339
Query: 301 GTC-----CPVCDGCFLNGREHRSGEPVGSGDPCSHCRCANGSVQCEPLPCP 347
G C CP C +G+ + G + C+ C C N C CP
Sbjct: 340 GLCVESTECP----CVHSGKRYPPGTSLSRD--CNTCICRNSQWICSNEECP 385
Score = 31.2 bits (69), Expect = 4.0
Identities = 41/169 (24%), Positives = 56/169 (33%), Gaps = 52/169 (30%)
Query: 345 PCPPVPCRHPGKIPGQCCPV--CDGCEYQGHQYQSQETFRLQERGLCVRCSCQAGEVSCE 402
P V C+HP + CPV +GC C G++ E
Sbjct: 1151 PACQVTCQHPEPL---ACPVQCVEGCH----------------------AHCPPGKILDE 1185
Query: 403 EQECPVTPCALPASGRQLCPACELDGEEFAEG--VQWEP-DGRPCTACVCQDGVPKCGAV 459
+ V P + CP CE+ G FA G V P D C C C C A
Sbjct: 1186 LLQTCVDP--------EDCPVCEVAGRRFASGKKVTLNPSDPEHCQICHCDVVNLTCEA- 1236
Query: 460 LCPPAPCQHPTQPPGACCPSCDSCTYHSQVYANGQNFTDADSPCHACHC 508
CQ +P G P D+ + +Y ++ P H +C
Sbjct: 1237 ------CQ---EPGGLVVPPTDAPVSPTTLYVE----DISEPPLHDFYC 1272
Score = 30.8 bits (68), Expect = 5.3
Identities = 36/157 (22%), Positives = 48/157 (30%), Gaps = 18/157 (11%)
Query: 392 CSCQAGEVSCEEQECPVTPCALPASGRQLCP-ACELDG-EEFAEGVQWEPDG-RPCTACV 448
C+C ++ C + LCP +CE E +W + P
Sbjct: 1097 CACFCDTIAAYAHVCAQHGKVVTWRTATLCPQSCEERNLRENGYECEWRYNSCAPACQVT 1156
Query: 449 CQDGVPKCGAVLCPPAPCQHPTQPPGACCPS----------CDSCTYHSQVYANGQNFTD 498
CQ P V C C H PPG C C + +A+G+ T
Sbjct: 1157 CQHPEPLACPVQCVEG-C-HAHCPPGKILDELLQTCVDPEDCPVCEVAGRRFASGKKVTL 1214
Query: 499 ADSP---CHACHCQDGTVTCSLVDCPPTTCARPQSGP 532
S C CHC +TC P P P
Sbjct: 1215 NPSDPEHCQICHCDVVNLTCEACQEPGGLVVPPTDAP 1251
Score = 30.8 bits (68), Expect = 5.3
Identities = 23/88 (26%), Positives = 31/88 (35%), Gaps = 22/88 (25%)
Query: 110 EPDACTACVCQDGAAHCGPQAHLPH----------CRGCSQNGQTYGNGETFS-----PD 154
EP AC + AHC P L C C G+ + +G+ + P+
Sbjct: 1161 EPLACPVQCVEGCHAHCPPGKILDELLQTCVDPEDCPVCEVAGRRFASGKKVTLNPSDPE 1220
Query: 155 ACTTCRCLEGTITCNQKPCPRGPCPEPG 182
C C C +TC C EPG
Sbjct: 1221 HCQICHCDVVNLTCE-------ACQEPG 1241
>gi|122937343 platelet endothelial aggregation receptor 1 [Homo
sapiens]
Length = 1037
Score = 78.6 bits (192), Expect = 2e-14
Identities = 174/694 (25%), Positives = 222/694 (31%), Gaps = 193/694 (27%)
Query: 121 DGAAHCGPQAHLPHC-RGCSQNGQTYGNGETFSPDACTTCRCLEGTITCN-QKPCPRG-- 176
D ++ C P P C + CS GN + P + C C G N +PC G
Sbjct: 130 DCSSECAPGMWGPQCDKPCS-----CGNNSSCDPKS-GVCSCPSGLQPPNCLQPCTPGYY 183
Query: 177 -------------PC-PEPGAC-CP--HCKPGCDYEGQLYEEGVTFLSSSNPCLQCTCLR 219
PC P+ GAC CP P CD G F S++ C +
Sbjct: 184 GPACQFRCQCHGAPCDPQTGACFCPAERTGPSCDVSCSQGTSGF-FCPSTHSCQNGGVFQ 242
Query: 220 SRVRCMALKCPPS--------PCPEPVLRPGHCCPTCQGCTEGGSHWEHGQEWTTPGDPC 271
+ + CPP PCPE P +C C+ C GG +
Sbjct: 243 TPQG--SCSCPPGWMGTICSLPCPEGFHGP-NCSQECR-CHNGGLCDRFTGQ-------- 290
Query: 272 RICRCLEGHI--QCRQ--------RECASLCPYP--ARPLPGTCCPVCDGCFLNGREHRS 319
CRC G+ +CR+ ++CA C AR P +C+ F
Sbjct: 291 --CRCAPGYTGDRCREECPVGRFGQDCAETCDCAPDARCFPANGACLCEHGF-------- 340
Query: 320 GEPVGSGDPCSHCRCANG--SVQCE-PLPCP---PVPCRHPGKIPGQCCPVCDGCEYQGH 373
+GD C+ C +G + C+ P C + C HP C P G
Sbjct: 341 -----TGDRCTDRLCPDGFYGLSCQAPCTCDREHSLSC-HPMNGECSCLPGWAGLHCNES 394
Query: 374 QYQSQETFRLQERGLCVRCS-CQAGEVSCE----------EQECPVTPCALPASGRQLCP 422
Q QE LC+ CQA C+ CP + S R C
Sbjct: 395 CPQDTHGPGCQEHCLCLHGGVCQATSGLCQCAPGYTGPHCASLCPPDTYGVNCSARCSCE 454
Query: 423 ---ACE-LDGEEFAEGVQWEPDGRPCTACVCQDGVPKCGAVLCPPAPCQHPTQPPGACCP 478
AC +DGE CVC++G + + PC PPG
Sbjct: 455 NAIACSPIDGE-----------------CVCKEGWQRGNCSV----PC-----PPGTWGF 488
Query: 479 SCD-SCTYHSQVYANGQNFTDADSP-CHACHCQDGTVTCSLVDCPPTTCARPQSGPGQCC 536
SC+ SC + + Q +P H HCQ C + Q G G C
Sbjct: 489 SCNASCQCAHEAVCSPQTGACTCTPGWHGAHCQ-------------LPCPKGQFGEG-CA 534
Query: 537 PRCPDCILEEEVFVDGESFSHPRDPCQECRCQEGH--AHCQPRPCPRAPCAHPLPGTCCP 594
RC DC DG H R C+CQ G A C C L G C
Sbjct: 535 SRC-DCDHS-----DGCDPVHGR-----CQCQAGWMGARCH------LSCPEGLWGVNCS 577
Query: 595 NDCSGCAFGGKEYPSGADF---PHPSDPCRLCRCLSGNVQCLARRCVPLPCPEPVL---- 647
N C+ C GG P + P P C G +RCVP C
Sbjct: 578 NTCT-CKNGGTCLPENGNCVCAPGFRGPSCQRSCQPGRY---GKRCVPCKCANHSFCHPS 633
Query: 648 ------LPGECCPQCPAAPAPAG-----------CPRPGAAHARHQEYFSPPGDPCRRCL 690
L G P C + P P G C G H + P G CL
Sbjct: 634 NGTCYCLAGWTGPDC-SQPCPPGHWGENCAQTCQCHHGGTCHPQDGSCICPLGWTGHHCL 692
Query: 691 --CLDGSVSC---QRLPCPPAPCAHPRQGPC-CP 718
C G+ Q C P HP G C CP
Sbjct: 693 EGCPLGTFGANCSQPCQCGPGEKCHPETGACVCP 726
Score = 57.0 bits (136), Expect = 7e-08
Identities = 105/455 (23%), Positives = 137/455 (30%), Gaps = 138/455 (30%)
Query: 86 SCECHPASPQC-----WG---LGRAWPEGARWEPDACTACVC--------QDGAAHCGPQ 129
S CHP + +C W + P+ P C+C G C P
Sbjct: 370 SLSCHPMNGECSCLPGWAGLHCNESCPQDTHG-PGCQEHCLCLHGGVCQATSGLCQCAPG 428
Query: 130 AHLPHCRGCSQNGQTYGNGETFSPDACTTCRCLEGTITCN----QKPCPRGPCPEPGACC 185
PHC +T+ + C C E I C+ + C G + G C
Sbjct: 429 YTGPHCASLCPP-------DTYGVNCSARCSC-ENAIACSPIDGECVCKEGW--QRGNCS 478
Query: 186 PHCKPG-----CDYEGQLYEEGVTFLSSSNPCLQCTCLRSRVRCMALKCPPSPCPEPVLR 240
C PG C+ Q E V S CT C PCP+
Sbjct: 479 VPCPPGTWGFSCNASCQCAHEAVC--SPQTGACTCTPGWHGAHCQL------PCPKGQFG 530
Query: 241 PGHCCPTCQGCTEGGSHWEHGQEWTTPGDPCRICRCLEG------HIQCRQR----ECAS 290
G C C G HG+ C+C G H+ C + C++
Sbjct: 531 EG-CASRCDCDHSDGCDPVHGR-----------CQCQAGWMGARCHLSCPEGLWGVNCSN 578
Query: 291 LCPYPARPLPGTCCP-----VCDGCFLNGREHRSGEPVGSGDPCSHCRCANGSVQCEP-- 343
C GTC P VC F RS +P G C C+CAN S C P
Sbjct: 579 TCTCKNG---GTCLPENGNCVCAPGFRGPSCQRSCQPGRYGKRCVPCKCANHSF-CHPSN 634
Query: 344 ---------------LPCPPVPCRHPGKIPGQCCPVCDGCEYQGHQYQSQETFRLQERGL 388
PCPP H G+ Q C C + G
Sbjct: 635 GTCYCLAGWTGPDCSQPCPP---GHWGENCAQTCQ----CHHGG---------------- 671
Query: 389 CVRCSCQAGEVSCEEQECPVTPCALPASGRQLCPACELDGEEFAEGVQWEPDGRPCTACV 448
+C + SC C L +G C L G +PC
Sbjct: 672 ----TCHPQDGSC--------ICPLGWTGHHCLEGCPL-------GTFGANCSQPCQCGP 712
Query: 449 CQDGVPKCGAVLCPP----APCQHPTQPPGACCPS 479
+ P+ GA +CPP APC+ Q P P+
Sbjct: 713 GEKCHPETGACVCPPGHSGAPCRIGIQEPFTVMPT 747
Score = 44.3 bits (103), Expect = 5e-04
Identities = 113/473 (23%), Positives = 136/473 (28%), Gaps = 154/473 (32%)
Query: 347 PPVPCRHPGKIPGQCC-PVCDGCEYQGHQYQSQETFRLQ-------ERGLCVRCSCQAGE 398
P PC P + P C P ++ RLQ RG CV Q
Sbjct: 51 PSEPCERPWEGPHTCPQPTVVYRTVYRQVVKTDHRQRLQCCHGFYESRGFCVPLCAQ--- 107
Query: 399 VSCEEQECPVTPCALPASGRQLCPACELD--GEEFAEGVQWEPD-GRPCTACVCQDGVPK 455
EC C P + Q P D E A G+ W P +PC+ PK
Sbjct: 108 ------ECVHGRCVAP-NQCQCVPGWRGDDCSSECAPGM-WGPQCDKPCSCGNNSSCDPK 159
Query: 456 CGAVLCP----PAPCQHPTQPPGACCPSCDSCTYHSQVYANGQNFTDADSPCHACHCQDG 511
G CP P C P P G P+C + Q CH C
Sbjct: 160 SGVCSCPSGLQPPNCLQPCTP-GYYGPACQ---FRCQ--------------CHGAPCDPQ 201
Query: 512 TVTCSLVDCPP--------TTCARPQSGPGQCCPRCPDCILEEEVFVDGESFSHPRDPCQ 563
T C CP +C++ SG CP C +G F P+ C
Sbjct: 202 TGACF---CPAERTGPSCDVSCSQGTSG--FFCPSTHSC-------QNGGVFQTPQGSCS 249
Query: 564 ECRCQEGHAHCQPRPCPRAPCAHPLPGTCCPNDCSGCAFGGKEYPSGADFPHPSDPCR-- 621
C GT C C P G P+ S CR
Sbjct: 250 --------------------CPPGWMGTICSLPC----------PEGFHGPNCSQECRCH 279
Query: 622 ---LCRCLSGNVQCL----ARRCVPLPCPEPVLLPGECCPQCPAAPAPAGCPRPGAAHAR 674
LC +G +C RC CP +C C AP P GA
Sbjct: 280 NGGLCDRFTGQCRCAPGYTGDRCRE-ECPVG-RFGQDCAETCDCAPDARCFPANGACLCE 337
Query: 675 HQEYFSPPGDPCRRCLCLDG--SVSCQRLPCPPAPCAHPRQGPCCPSCDGCLYQGKEFAS 732
H GD C LC DG +SCQ APC +CD
Sbjct: 338 H----GFTGDRCTDRLCPDGFYGLSCQ------APC----------TCDR---------- 367
Query: 733 GERFPSPTAACHLCLCWEGSVSCEPKACAPALCPFPARGDCCPDCDGEGHGIG 785
E S+SC P + P A C C + HG G
Sbjct: 368 -----------------EHSLSCHPMNGECSCLPGWAGLHCNESCPQDTHGPG 403
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.323 0.141 0.523
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 49,430,117
Number of Sequences: 37866
Number of extensions: 3398726
Number of successful extensions: 19705
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 96
Number of HSP's successfully gapped in prelim test: 468
Number of HSP's that attempted gapping in prelim test: 12023
Number of HSP's gapped (non-prelim): 3712
length of query: 814
length of database: 18,247,518
effective HSP length: 111
effective length of query: 703
effective length of database: 14,044,392
effective search space: 9873207576
effective search space used: 9873207576
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.