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Search of human proteins with 209180481
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|209180481 Cas-Br-M (murine) ecotropic retroviral
transforming sequence-like 1 [Homo sapiens]
(491 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|209180481 Cas-Br-M (murine) ecotropic retroviral transforming... 1089 0.0
gi|22749189 zinc finger protein 645 [Homo sapiens] 450 e-126
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo... 93 5e-19
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ... 93 5e-19
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 91 2e-18
gi|117306167 proline-rich protein BstNI subfamily 3 precursor [H... 90 4e-18
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin... 89 1e-17
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 88 2e-17
gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens] 87 3e-17
gi|11386183 WAS protein family, member 2 [Homo sapiens] 86 1e-16
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ... 85 1e-16
gi|42544130 splicing factor 1 isoform 1 [Homo sapiens] 85 1e-16
gi|150417989 cyclin K isoform 1 [Homo sapiens] 85 1e-16
gi|162329583 cleavage and polyadenylation specific factor 6, 68 ... 85 2e-16
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 84 2e-16
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 84 2e-16
gi|151301053 RNA binding motif protein 33 [Homo sapiens] 84 2e-16
gi|160707881 formin 2 [Homo sapiens] 84 3e-16
gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [... 83 6e-16
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] 83 6e-16
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] 83 6e-16
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] 83 6e-16
gi|47132519 Ras association and pleckstrin homology domains 1 is... 82 8e-16
gi|37537692 proline-rich protein BstNI subfamily 4 precursor [Ho... 82 1e-15
gi|116284392 mucin 2 precursor [Homo sapiens] 81 2e-15
gi|4507909 Wiskott-Aldrich syndrome protein [Homo sapiens] 80 5e-15
gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sap... 80 5e-15
gi|91199543 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo s... 80 5e-15
gi|33636768 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo s... 80 5e-15
gi|55750053 atrophin-1 [Homo sapiens] 79 7e-15
>gi|209180481 Cas-Br-M (murine) ecotropic retroviral transforming
sequence-like 1 [Homo sapiens]
Length = 491
Score = 1089 bits (2816), Expect = 0.0
Identities = 491/491 (100%), Positives = 491/491 (100%)
Query: 1 MDHTDNELQGTNSSGSLGGLDVRRRIPIKLISKQANKAKPAPRTQRTINRMPAKAPPGDE 60
MDHTDNELQGTNSSGSLGGLDVRRRIPIKLISKQANKAKPAPRTQRTINRMPAKAPPGDE
Sbjct: 1 MDHTDNELQGTNSSGSLGGLDVRRRIPIKLISKQANKAKPAPRTQRTINRMPAKAPPGDE 60
Query: 61 EGFDYNEEERYDCKGGELFANQRRFPGHLFWDFQINILGEKDDTPVHFCDKCGLPIKIYG 120
EGFDYNEEERYDCKGGELFANQRRFPGHLFWDFQINILGEKDDTPVHFCDKCGLPIKIYG
Sbjct: 61 EGFDYNEEERYDCKGGELFANQRRFPGHLFWDFQINILGEKDDTPVHFCDKCGLPIKIYG 120
Query: 121 RMIPCKHVFCYDCAILHEKKGDKMCPGCSDPVQRIEQCTRGSLFMCSIVQGCKRTYLSQR 180
RMIPCKHVFCYDCAILHEKKGDKMCPGCSDPVQRIEQCTRGSLFMCSIVQGCKRTYLSQR
Sbjct: 121 RMIPCKHVFCYDCAILHEKKGDKMCPGCSDPVQRIEQCTRGSLFMCSIVQGCKRTYLSQR 180
Query: 181 DLQAHINHRHMRAGKPVTRASLENVHPPIAPPPTEIPERFIMPPDKHHMSHIPPKQHIMM 240
DLQAHINHRHMRAGKPVTRASLENVHPPIAPPPTEIPERFIMPPDKHHMSHIPPKQHIMM
Sbjct: 181 DLQAHINHRHMRAGKPVTRASLENVHPPIAPPPTEIPERFIMPPDKHHMSHIPPKQHIMM 240
Query: 241 PPPPLQHVPHEHYNQPHEDIRAPPAELSMAPPPPRSVSQETFRISTRKHSNLITVPIQDD 300
PPPPLQHVPHEHYNQPHEDIRAPPAELSMAPPPPRSVSQETFRISTRKHSNLITVPIQDD
Sbjct: 241 PPPPLQHVPHEHYNQPHEDIRAPPAELSMAPPPPRSVSQETFRISTRKHSNLITVPIQDD 300
Query: 301 SNSGAREPPPPAPAPAHHHPEYQGQPVVSHPHHIMPPQQHYAPPPPPPPPISHPMPHPPQ 360
SNSGAREPPPPAPAPAHHHPEYQGQPVVSHPHHIMPPQQHYAPPPPPPPPISHPMPHPPQ
Sbjct: 301 SNSGAREPPPPAPAPAHHHPEYQGQPVVSHPHHIMPPQQHYAPPPPPPPPISHPMPHPPQ 360
Query: 361 AAGTPHLVYSQAPPPPMTSAPPPITPPPGHIIAQMPPYMNHPPPGPPPPQHGGPPVTAPP 420
AAGTPHLVYSQAPPPPMTSAPPPITPPPGHIIAQMPPYMNHPPPGPPPPQHGGPPVTAPP
Sbjct: 361 AAGTPHLVYSQAPPPPMTSAPPPITPPPGHIIAQMPPYMNHPPPGPPPPQHGGPPVTAPP 420
Query: 421 PHHYNPNSLPQFTEDQGTLSPPFTQPGGMSPGIWPAPRGPPPPPRLQGPPSQTPLPGPHH 480
PHHYNPNSLPQFTEDQGTLSPPFTQPGGMSPGIWPAPRGPPPPPRLQGPPSQTPLPGPHH
Sbjct: 421 PHHYNPNSLPQFTEDQGTLSPPFTQPGGMSPGIWPAPRGPPPPPRLQGPPSQTPLPGPHH 480
Query: 481 PDQTRYRPYYQ 491
PDQTRYRPYYQ
Sbjct: 481 PDQTRYRPYYQ 491
>gi|22749189 zinc finger protein 645 [Homo sapiens]
Length = 425
Score = 450 bits (1158), Expect = e-126
Identities = 229/436 (52%), Positives = 285/436 (65%), Gaps = 13/436 (2%)
Query: 54 KAPPGDEEGFDYNEEERYDCKGGELFANQRRFPGHLFWDFQINILGEKDDTPVHFCDKCG 113
K P G++E +YN+E +Y KG +L +++ PG+ + D +INI+GEKDD P+HFCDKC
Sbjct: 3 KMPAGEQE-CEYNKEGKYYSKGVKLVRKKKKIPGYRWGDIKINIIGEKDDLPIHFCDKCD 61
Query: 114 LPIKIYGRMIPCKHVFCYDCAILHEKKGDKMCPGCSDPVQRIEQCTRGSLFMCSIVQGCK 173
LPIKIYGR+IPCKH FCY CA L++K G K+CP C PV RIE RGS+FMCSIVQ CK
Sbjct: 62 LPIKIYGRIIPCKHAFCYHCANLYDKVGYKVCPRCRYPVLRIEAHKRGSVFMCSIVQQCK 121
Query: 174 RTYLSQRDLQAHINHRHMRAGKPVTRASLENVHPPIAPPPTEIPERFIMPPDKHHMSHIP 233
RTYLSQ+ LQAHI RH RA K VT ASLE V P IAPP TEI + D+ H+S+IP
Sbjct: 122 RTYLSQKSLQAHIKRRHKRARKQVTSASLEKVRPHIAPPQTEISDIPKRLQDRDHLSYIP 181
Query: 234 PKQHIMMPPPPLQHVPHEHYNQPHEDIRAPPAELSMAPPPPRSVSQETFRISTRKHSNLI 293
P+QH M+ P +QH+ E +NQPH+DI+APP ELS++ P P + ET I TRKH NL
Sbjct: 182 PEQHTMVSLPSVQHMLQEQHNQPHKDIQAPPPELSLSLPFP--IQWETVSIFTRKHGNLT 239
Query: 294 TVPIQDDSNSGAREPPPPAPAPAHHHPEYQGQPVVSHPHHIMPPQQHYAPPPPPPPPISH 353
IQ++S+SGA++P PP ++PE Q QP VS PHHI+P +QHYAPPP P P++H
Sbjct: 240 VDHIQNNSDSGAKKPTPP-----DYYPECQSQPAVSSPHHIIPQKQHYAPPPSPSSPVNH 294
Query: 354 PMPHPPQAAGTPHLVYSQAPPPPMTSAPPPITPPPGHIIAQMPPYMNHPPPGPPPPQHGG 413
MP+PPQ TP+ V SQ P T P G+II ++PP MN PP P Q+G
Sbjct: 295 QMPYPPQDVVTPNSVRSQVPALTTT-----YDPSSGYIIVKVPPDMNSPPLRAPQSQNGN 349
Query: 414 PPVTAPPPHHYNPNSLPQFTEDQGTLSPPFTQPGGMSPGIWPAPRGPPPPPRLQGPPSQT 473
P + HHYN N LPQFTE+Q TLSP FTQ M WPA + P P + PP T
Sbjct: 350 PSASEFASHHYNLNILPQFTENQETLSPQFTQTDAMDHRRWPAWKRLSPCPPTRSPPPST 409
Query: 474 PLPGPHHPDQTRYRPY 489
HH Q R+R Y
Sbjct: 410 LHGRSHHSHQRRHRRY 425
>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 93.2 bits (230), Expect = 5e-19
Identities = 86/311 (27%), Positives = 116/311 (37%), Gaps = 57/311 (18%)
Query: 192 RAGKPVTRASLENVH------PPIAPP-----------PTEIPERFIMPPDKHHMSHIPP 234
+AG P R++ + PP+ PP P P RF +P H P
Sbjct: 105 QAGMPKLRSTANRDNDSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEP 164
Query: 235 KQHIMMPPPPLQHVPHEHYNQPHEDIRAPPAELSMAPPPPRSVSQETFRISTRKHSNLIT 294
+++ M PP P D+ + P + PPP S + I + H N +
Sbjct: 165 QRNRMPPPRP--------------DVGSKPDSI---PPPVPSTPRP---IQSSPH-NRGS 203
Query: 295 VPIQDDSNSGAREPPP---PAPAPAHHHPEYQGQPVVSHPHHIMPPQQHYAPPPPPPPPI 351
P+ G R+P P P P P + G + P P + P PP P
Sbjct: 204 PPVP----GGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRA 259
Query: 352 --SHPMPHPPQAAGTPHLVYSQAPPPPMTSAPPPITPPPGHIIAQMPPYMNHPPPGPPPP 409
P P PP P + PPPP + PP+ P + P PP PPP
Sbjct: 260 LDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAP-----PPPPPPS 314
Query: 410 QHGGPPVTAPPPHHYNPNS--LPQFTEDQGTLSPPFTQPGGMSPGIWPAPRGPPPPPRLQ 467
+ G PP+ PP N + LPQ + +PP PG P + P P PPPP
Sbjct: 315 RPGPPPL--PPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGP-LPPPPSERPPPPVRD 371
Query: 468 GPPSQTPLPGP 478
P PLP P
Sbjct: 372 PPGRSGPLPPP 382
Score = 61.6 bits (148), Expect = 2e-09
Identities = 56/223 (25%), Positives = 75/223 (33%), Gaps = 39/223 (17%)
Query: 196 PVTRASLENVHPPIAPPPTEIPERFIMPPDKHHMSHIPPKQHIMMPPPPLQHVPHEHYNQ 255
P++ +S + PP+ P P+ + PP + + P +PPPP Q+ N+
Sbjct: 239 PLSSSSPFSNRPPLPPTPSRALDDK-PPPPPPPVGNRPSIHREAVPPPPPQN------NK 291
Query: 256 PHEDIRAPPAELSMAPPPPRSVSQETFRISTRKHSNLITVPIQDDSNSGAREPPPPAPAP 315
P P+ S APPPP S+ S P N PP P+P
Sbjct: 292 PPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSP 351
Query: 316 AHHHPEYQGQPVVSHPHHIMPPQQHYAPPP-----------PPPPPISHPMPHPPQAAGT 364
P + PP PPP PPPPP+S T
Sbjct: 352 GRSGP-------------LPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPAT 398
Query: 365 PHLVYSQAPPPPMTSAPPPITPPPGHIIAQMPPYMNHPPPGPP 407
P L P + PP+ P P PPP PP
Sbjct: 399 PQLPSRSGVDSPRSGPRPPLPPD--------RPSAGAPPPPPP 433
Score = 55.1 bits (131), Expect = 1e-07
Identities = 47/158 (29%), Positives = 60/158 (37%), Gaps = 16/158 (10%)
Query: 343 PPPPPPPPISHPMPHPPQAAGTPHLVYSQAPPP------PMTSAPPPITPPPGHIIAQMP 396
P PP P P+P P +G P ++ PPP S PPP+ P I Q
Sbjct: 140 PFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPI--QSS 197
Query: 397 PYMNHPPPGPPPPQHGGPPVTAPPPHHYNPNSLPQFTEDQGTLSPPFTQPGGMSPGIWPA 456
P+ PP P P+ P T PP +L + Q LS + P P + P
Sbjct: 198 PHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSS--SSPFSNRPPLPPT 255
Query: 457 P------RGPPPPPRLQGPPSQTPLPGPHHPDQTRYRP 488
P + PPPPP + PS P P Q P
Sbjct: 256 PSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPP 293
Score = 34.3 bits (77), Expect = 0.26
Identities = 41/134 (30%), Positives = 46/134 (34%), Gaps = 33/134 (24%)
Query: 362 AGTPHLVYSQAPPPPMTSAPPPITPPPGHIIAQMPPYMNHPPPGPPPPQHGGPPVTAPPP 421
AG P L + + PP+ PP G + P PP GP G PV +P
Sbjct: 106 AGMPKLRSTANRDNDSGGSRPPLLPPGGRSTSAKP---FSPPSGP-----GRFPVPSPG- 156
Query: 422 HHYNPNSLPQFTEDQGTLSPPFTQPGGMSPGIWPAP--------------RGPPPPPRLQ 467
H P E Q PP G P P P RG PP P
Sbjct: 157 HRSGP------PEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVP--- 207
Query: 468 GPPSQTPLPGPHHP 481
G P Q P PGP P
Sbjct: 208 GGPRQ-PSPGPTPP 220
Score = 32.3 bits (72), Expect = 1.0
Identities = 30/110 (27%), Positives = 34/110 (30%), Gaps = 29/110 (26%)
Query: 405 GPPPPQHGGPPVTAPPPHHYNPNSLPQFTEDQGTLSPPFTQPGGMS-----------PGI 453
G PP GG P N D G PP PGG S PG
Sbjct: 94 GGGPPGLGGLFQAGMPKLRSTANR----DNDSGGSRPPLLPPGGRSTSAKPFSPPSGPGR 149
Query: 454 WPAP--------------RGPPPPPRLQGPPSQTPLPGPHHPDQTRYRPY 489
+P P R PPP P + P P P P P + P+
Sbjct: 150 FPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPH 199
>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 93.2 bits (230), Expect = 5e-19
Identities = 86/311 (27%), Positives = 116/311 (37%), Gaps = 57/311 (18%)
Query: 192 RAGKPVTRASLENVH------PPIAPP-----------PTEIPERFIMPPDKHHMSHIPP 234
+AG P R++ + PP+ PP P P RF +P H P
Sbjct: 105 QAGMPKLRSTANRDNDSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEP 164
Query: 235 KQHIMMPPPPLQHVPHEHYNQPHEDIRAPPAELSMAPPPPRSVSQETFRISTRKHSNLIT 294
+++ M PP P D+ + P + PPP S + I + H N +
Sbjct: 165 QRNRMPPPRP--------------DVGSKPDSI---PPPVPSTPRP---IQSSPH-NRGS 203
Query: 295 VPIQDDSNSGAREPPP---PAPAPAHHHPEYQGQPVVSHPHHIMPPQQHYAPPPPPPPPI 351
P+ G R+P P P P P + G + P P + P PP P
Sbjct: 204 PPVP----GGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRA 259
Query: 352 --SHPMPHPPQAAGTPHLVYSQAPPPPMTSAPPPITPPPGHIIAQMPPYMNHPPPGPPPP 409
P P PP P + PPPP + PP+ P + P PP PPP
Sbjct: 260 LDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAP-----PPPPPPS 314
Query: 410 QHGGPPVTAPPPHHYNPNS--LPQFTEDQGTLSPPFTQPGGMSPGIWPAPRGPPPPPRLQ 467
+ G PP+ PP N + LPQ + +PP PG P + P P PPPP
Sbjct: 315 RPGPPPL--PPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGP-LPPPPSERPPPPVRD 371
Query: 468 GPPSQTPLPGP 478
P PLP P
Sbjct: 372 PPGRSGPLPPP 382
Score = 61.6 bits (148), Expect = 2e-09
Identities = 56/223 (25%), Positives = 75/223 (33%), Gaps = 39/223 (17%)
Query: 196 PVTRASLENVHPPIAPPPTEIPERFIMPPDKHHMSHIPPKQHIMMPPPPLQHVPHEHYNQ 255
P++ +S + PP+ P P+ + PP + + P +PPPP Q+ N+
Sbjct: 239 PLSSSSPFSNRPPLPPTPSRALDDK-PPPPPPPVGNRPSIHREAVPPPPPQN------NK 291
Query: 256 PHEDIRAPPAELSMAPPPPRSVSQETFRISTRKHSNLITVPIQDDSNSGAREPPPPAPAP 315
P P+ S APPPP S+ S P N PP P+P
Sbjct: 292 PPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSP 351
Query: 316 AHHHPEYQGQPVVSHPHHIMPPQQHYAPPP-----------PPPPPISHPMPHPPQAAGT 364
P + PP PPP PPPPP+S T
Sbjct: 352 GRSGP-------------LPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPAT 398
Query: 365 PHLVYSQAPPPPMTSAPPPITPPPGHIIAQMPPYMNHPPPGPP 407
P L P + PP+ P P PPP PP
Sbjct: 399 PQLPSRSGVDSPRSGPRPPLPPD--------RPSAGAPPPPPP 433
Score = 55.1 bits (131), Expect = 1e-07
Identities = 47/158 (29%), Positives = 60/158 (37%), Gaps = 16/158 (10%)
Query: 343 PPPPPPPPISHPMPHPPQAAGTPHLVYSQAPPP------PMTSAPPPITPPPGHIIAQMP 396
P PP P P+P P +G P ++ PPP S PPP+ P I Q
Sbjct: 140 PFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPI--QSS 197
Query: 397 PYMNHPPPGPPPPQHGGPPVTAPPPHHYNPNSLPQFTEDQGTLSPPFTQPGGMSPGIWPA 456
P+ PP P P+ P T PP +L + Q LS + P P + P
Sbjct: 198 PHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSS--SSPFSNRPPLPPT 255
Query: 457 P------RGPPPPPRLQGPPSQTPLPGPHHPDQTRYRP 488
P + PPPPP + PS P P Q P
Sbjct: 256 PSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPP 293
Score = 34.3 bits (77), Expect = 0.26
Identities = 41/134 (30%), Positives = 46/134 (34%), Gaps = 33/134 (24%)
Query: 362 AGTPHLVYSQAPPPPMTSAPPPITPPPGHIIAQMPPYMNHPPPGPPPPQHGGPPVTAPPP 421
AG P L + + PP+ PP G + P PP GP G PV +P
Sbjct: 106 AGMPKLRSTANRDNDSGGSRPPLLPPGGRSTSAKP---FSPPSGP-----GRFPVPSPG- 156
Query: 422 HHYNPNSLPQFTEDQGTLSPPFTQPGGMSPGIWPAP--------------RGPPPPPRLQ 467
H P E Q PP G P P P RG PP P
Sbjct: 157 HRSGP------PEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVP--- 207
Query: 468 GPPSQTPLPGPHHP 481
G P Q P PGP P
Sbjct: 208 GGPRQ-PSPGPTPP 220
Score = 32.3 bits (72), Expect = 1.0
Identities = 30/110 (27%), Positives = 34/110 (30%), Gaps = 29/110 (26%)
Query: 405 GPPPPQHGGPPVTAPPPHHYNPNSLPQFTEDQGTLSPPFTQPGGMS-----------PGI 453
G PP GG P N D G PP PGG S PG
Sbjct: 94 GGGPPGLGGLFQAGMPKLRSTANR----DNDSGGSRPPLLPPGGRSTSAKPFSPPSGPGR 149
Query: 454 WPAP--------------RGPPPPPRLQGPPSQTPLPGPHHPDQTRYRPY 489
+P P R PPP P + P P P P P + P+
Sbjct: 150 FPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPH 199
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 90.9 bits (224), Expect = 2e-18
Identities = 99/321 (30%), Positives = 126/321 (39%), Gaps = 61/321 (19%)
Query: 196 PVTRASLENVHPPIAPPPTEIPERFIMPPDKHHMSHIPPKQHIMMPPPPLQH-VPHEHYN 254
P + SL P++ P T P + + H S P ++MPP Q +
Sbjct: 467 PPLQTSLSPAVSPLSSPLTIHPLQALSSLASH--SPQAPLSSLIMPPLETQSSLAPPSLQ 524
Query: 255 QPHEDIRAPPAEL--SMAPPPPRSVSQE--TFRIST----------RKHSNLITVPIQDD 300
P + PP E S+APPP ++ S T + T S L T P +
Sbjct: 525 TPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPP--PE 582
Query: 301 SNSGAREPPPPAPAPAHHHPEYQG-----------QPVVSHPHHIMPPQQHYAPPPPPPP 349
+ S PPP AP PA P QG P + P +PP Q PP PP
Sbjct: 583 TPSSIATPPPQAP-PALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPP 641
Query: 350 --PISHPMPHPPQAAGTPHLVYSQAPPPPMTSAPPPITPPPGHIIA-------QMPPYMN 400
P++ P P P A HL+ + PPP P +PP ++ Q PP +
Sbjct: 642 LSPLATPSPQAPNALAV-HLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLA 700
Query: 401 HPP----PGPP--PPQHGG--PPVTAPPPHHYNPNSLPQFTEDQGTLSPPFTQPGGMSPG 452
PP P PP PP PP APPP P +P SPP + P MSP
Sbjct: 701 APPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPP--------SPPASPP--MSPS 750
Query: 453 IWPAPRGPP--PPPRLQGPPS 471
P PR PP P LQ PPS
Sbjct: 751 ATPPPRVPPLLAAPPLQVPPS 771
Score = 83.6 bits (205), Expect = 4e-16
Identities = 86/303 (28%), Positives = 112/303 (36%), Gaps = 43/303 (14%)
Query: 193 AGKPVTRASLENVHPPIAPPPTEIPERFIMPPDKHHMSHIPPKQHIMMPPPPLQHVPHEH 252
A P+ AS P + PP P PP ++ PP+ + PP Q P
Sbjct: 542 APPPLQTASAPLTTPHLETPPCPAPCPLQAPPSP--LTTPPPETPSSIATPPPQ-APPAL 598
Query: 253 YNQPHEDIRAPPAELSMAPPPPRSVSQETFRISTRKHSNLITVPIQDDSNSGAREPPPPA 312
+ P + + +PP +A PPP++ L P+Q + A P P
Sbjct: 599 ASPPLQGLPSPPLS-PLATPPPQAPPX------------LALPPLQAPPSPPASPPLSPL 645
Query: 313 PAPAHHHPEYQGQPVVSHPHHIMPPQQHYAPPPPPPPPISHPMPHPPQAA----GTPHLV 368
P+ P ++ P P AP PP P P PP A P L
Sbjct: 646 ATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQ 705
Query: 369 YSQAPP--PPMT--SAPPPITPPP-GHIIAQMPPYMNHPPPGPPPPQHGGPPVTAPPPHH 423
+PP PPM+ + PPP PPP Q+PP PP PP PP PP
Sbjct: 706 VPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPP---SPPASPPMSPSATPPPRVPPLLA 762
Query: 424 YNPNSLPQFTEDQGTLSPPFTQPGGMSPGIWPAPRGP-----PPPPRLQGPPSQTPLPGP 478
P +P SPP + P MSP P P+ P PP L PP+ P P
Sbjct: 763 APPLQVPP--------SPPASLP--MSPLAKPPPQAPPALATPPLQALPSPPASFPGQAP 812
Query: 479 HHP 481
P
Sbjct: 813 FSP 815
Score = 83.6 bits (205), Expect = 4e-16
Identities = 86/299 (28%), Positives = 112/299 (37%), Gaps = 47/299 (15%)
Query: 207 PPIAP---PPTEIPERFIMPPDKHHMSHIPPKQHIMMP--------PPPLQHVPHEHYNQ 255
PP++P PP++ P PP + S PP M P PPPL P +
Sbjct: 683 PPVSPSATPPSQAPPSLAAPPLQVPPS--PPASPPMSPSATPPPQAPPPLAAPPLQ---V 737
Query: 256 PHEDIRAPPAELSMAPPP--PRSVSQETFRISTRKHSNLITVPIQDDSNSGAREPPPPAP 313
P +PP S PPP P ++ ++ ++L P+ +PPP AP
Sbjct: 738 PPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLA--------KPPPQAP 789
Query: 314 APAHHHPEYQGQPVVSHPHHIMPPQQHYAPPPP-PPPPISHPMPHPPQAAGTPHLVYSQA 372
PA P Q P P P Q ++P P P++ P P P P L +
Sbjct: 790 -PALATPPLQALP---SPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPS 845
Query: 373 PPPPMTSAPPPITPPPGHIIAQMPPYMNHP-PPGPPPPQHGGPPVTAPPP----HHYNPN 427
PP T P P PG + P + PGPPPP P T P H +
Sbjct: 846 PPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSAT 905
Query: 428 SLPQFTE--DQG------TLSPPFTQPGGMSPGIWPAPRGPPPPPRLQGPPSQTPLPGP 478
S P+ D G PP + P W RGP PP +G P PLP P
Sbjct: 906 STPEELRGYDSGPEGGAAASPPPDAELAACHPAAW--SRGPAPPLAFRGAPG-APLPWP 961
Score = 83.2 bits (204), Expect = 5e-16
Identities = 104/361 (28%), Positives = 131/361 (36%), Gaps = 90/361 (24%)
Query: 196 PVTRASLENVHPPIAPPPTEIPERFIMPPDKHHMSHIPPKQHIMMPPPPLQHVPHEHYNQ 255
P SL+ + P A PP++ P PP M P Q I PP+Q VPH +
Sbjct: 348 PSAPPSLQTLPSPPATPPSQAPPSMTTPP----MQAPPSLQTI----PPIQ-VPH---SL 395
Query: 256 PHEDIRAPPAELSMAP--------PPPRSVSQETFRISTRKHSNLITVPIQDDSNSGARE 307
++APP+ L+++ P + +S R+ +T P + S
Sbjct: 396 TSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSP 455
Query: 308 P----------PP----------PAPAPAHHHPEYQGQPVVSHPHH------IMPP---Q 338
P PP P +P HP + SH IMPP Q
Sbjct: 456 PLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQ 515
Query: 339 QHYAPPPPPPPPIS---HPM-------PHPPQAAG----TPHLVYS--------QAPPPP 376
APP PP S P+ P P Q A TPHL QAPP P
Sbjct: 516 SSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSP 575
Query: 377 MTSAPPP-----ITPPPGHIIAQMPPYMNHPP----PGPPPPQHGGPPVTAPPPHHYNPN 427
+T+ PP TPPP Q PP + PP P PP PP APP P
Sbjct: 576 LTTPPPETPSSIATPPP-----QAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPL 630
Query: 428 SLPQFTEDQGTLSPPFT----QPGGMSPGIWPAPRGPPPPPRLQGPPSQTPLPGPHHPDQ 483
P LSP T P ++ + AP PPP P +Q P S P P P
Sbjct: 631 QAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFS-PPASPPVSPSA 689
Query: 484 T 484
T
Sbjct: 690 T 690
Score = 80.5 bits (197), Expect = 3e-15
Identities = 80/279 (28%), Positives = 105/279 (37%), Gaps = 36/279 (12%)
Query: 208 PIAPPPTEIPERFIMPPDKHHMSH--IPPKQHIMMPPPPLQHVPHEHYNQ-PHEDIRAPP 264
P+A PP + P +PP + S PP + P P + H Q P +PP
Sbjct: 613 PLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPP 672
Query: 265 AELSMAPPPPRSVSQETFRISTRKHSNLITVPIQDDSNSGAREPPPPAPAPAHHHPEYQG 324
+ +PP VS S S L P+Q + A P P+ P P
Sbjct: 673 VQAPFSPPASPPVSPSATPPSQAPPS-LAAPPLQVPPSPPASPPMSPSATPPPQAPPPLA 731
Query: 325 QPVVSHPHH--IMPPQQHYAPPPPPPPPISHPMPHPPQAAGTPHLVYSQAPPPPMTSAP- 381
P + P PP A PPP PP+ + PP Q PP P S P
Sbjct: 732 APPLQVPPSPPASPPMSPSATPPPRVPPL---LAAPP----------LQVPPSPPASLPM 778
Query: 382 -PPITPPPGHIIAQMPPYMNHPPPGPPPPQHGGPPVTAPPPHHYNPN-SLPQFTEDQGTL 439
P PPP Q PP + PP P PP + P ++P+ SLP
Sbjct: 779 SPLAKPPP-----QAPPALATPPLQALP----SPPASFPGQAPFSPSASLPM----SPLA 825
Query: 440 SPPFTQPGGMSPGIWPAPRGPPPPPRLQGPPSQTPLPGP 478
+PP P ++ + P PP P LQ P + P PGP
Sbjct: 826 TPPPQAPPVLAAPLLQVPPSPPASPTLQA-PRRPPTPGP 863
Score = 63.9 bits (154), Expect = 3e-10
Identities = 79/282 (28%), Positives = 99/282 (35%), Gaps = 37/282 (13%)
Query: 207 PPIAPPPTEIPERFIMPPDKHHMSHIPPKQHIMMPPPPLQHVPHEHYNQPHEDIRAPPAE 266
PP+A PP ++P P + PP+ ++ PPLQ P + P + PP +
Sbjct: 728 PPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQ 787
Query: 267 ---------LSMAPPPPRSV-SQETFRISTR-KHSNLITVPIQDDSNSGA---REPPPPA 312
L P PP S Q F S S L T P Q A + PP P
Sbjct: 788 APPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPP 847
Query: 313 PAPAHHHPEYQGQP----VVSHPHHIMPPQQHYAPPPPPPPP------ISHP--MPHPPQ 360
+P P P VS P + AP PPPPP +S P H
Sbjct: 848 ASPTLQAPRRPPTPGPDTSVSGPRLTLA----LAPGPPPPPSRSPSSTLSGPDLAGHSSS 903
Query: 361 AAGTPHLVYSQAPPPPMTSAPPPITPPPGHIIAQMPPYMNHPPPGPPPPQHGGPPVTAPP 420
A TP + P +A +PPP +A P P PP G P P
Sbjct: 904 ATSTPEELRGYDSGPEGGAAA---SPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPW 960
Query: 421 PHHYNPNS---LPQFTEDQGTLSPPFTQPGGMSPGIWPAPRG 459
P P S L E +G S PG + PG P G
Sbjct: 961 PPATGPGSADGLCTIYETEGPESAT-PAPGALDPGPSPGTSG 1001
Score = 60.5 bits (145), Expect = 3e-09
Identities = 85/338 (25%), Positives = 109/338 (32%), Gaps = 94/338 (27%)
Query: 198 TRASLENVHPPIAP-PPTEIPERFIMPPDKHHMSHIPPKQHIMMPPPPLQHVPHEHYNQP 256
T L P P PPTE P + + +H + P
Sbjct: 185 TEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAAR------------------- 225
Query: 257 HEDIRAPPAELSMAPPPPRSVSQETFRISTRKHSNLITVPIQDDSNSGAREPPPPAPAPA 316
R P A + P RS+S P+ + SG P APA
Sbjct: 226 ----RRPSAGGGLQRPASRSLSSSA-------------TPLSSPARSGPSARGTPR-APA 267
Query: 317 H-HHPEYQGQPVVSHPHHIMPPQQHYAPP--PPPPPPISHPMPH--------PPQAAGTP 365
H P+ +G + P + PP++ AP P P++ P P PP A TP
Sbjct: 268 HPSQPKPKGLQAL-RPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATP 326
Query: 366 HLVYSQAPPPPMTSAPPPITPPPGHIIAQMPPYMNHP--PPGPPPPQHGGPPVTAPP--- 420
+ + PP P + P P+ PP + + P PP PP PP+ APP
Sbjct: 327 --LPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQ 384
Query: 421 -------PHHYNPNSLP----------------------QFTEDQGTLSPPFTQPGGMSP 451
PH SL Q T T+SP TQ SP
Sbjct: 385 TIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSP 444
Query: 452 GIWPAPRGPPPPPRLQGPPSQTPLPGPHHPD-QTRYRP 488
P PP PP Q PL P P QT P
Sbjct: 445 S---RPASTPP----DSPPLQAPLSLPASPPLQTSLSP 475
Score = 60.1 bits (144), Expect = 5e-09
Identities = 91/355 (25%), Positives = 116/355 (32%), Gaps = 97/355 (27%)
Query: 207 PPIAPPPTEIPERFIMPPDKHHM---SHIPPKQHIMMP----------PPPLQHVPHEHY 253
P P P+ R + PPD + +PP + P PP LQ +P
Sbjct: 303 PLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPA 362
Query: 254 NQPHEDIRAPPAELSMAPPPPRSV-SQETFRISTRKHSNLITVPIQDDSNSGAREPPPPA 312
P + APP SM PP ++ S +T HS +T P + PP P
Sbjct: 363 TPPSQ---APP---SMTTPPMQAPPSLQTIPPIQVPHS--LTSP-------SLQAPPSPL 407
Query: 313 PAPAHHHPEYQGQPVVSHPHHI--MPPQQHYAP-----PPPPPPPISHPMPHPPQAAGTP 365
+ G P + H M P+Q A P PP S P+ P +P
Sbjct: 408 ALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASP 467
Query: 366 HL-------------------------VYSQAPPPPMTS------------APPPITPPP 388
L + S +P P++S APP + PP
Sbjct: 468 PLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPP 527
Query: 389 GHIIAQMPPYMNHPPPGPPP----------PQHGGPPVTAPPPHHYNPNSL---PQFTED 435
+ PP N P PPP P PP AP P P+ L P T
Sbjct: 528 ASLTT--PPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPS 585
Query: 436 QGTLSPPFTQPGGMSPGIWPAPRGP------PP---PPRLQGPPSQTPLPGPHHP 481
PP P SP + P P PP PP L PP Q P P P
Sbjct: 586 SIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASP 640
>gi|117306167 proline-rich protein BstNI subfamily 3 precursor [Homo
sapiens]
Length = 309
Score = 90.1 bits (222), Expect = 4e-18
Identities = 87/297 (29%), Positives = 103/297 (34%), Gaps = 31/297 (10%)
Query: 193 AGKPVTRASLENVHPPIAPPPTEIPERFIMPPDKHHMSHIPPKQHIMMPPPPLQHVPHEH 252
+GKP R P PPP PE PP + S PP + PP Q
Sbjct: 33 SGKPEGRRPQGGNQPQRTPPPPGKPEG--RPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQ 90
Query: 253 YNQPHE---DIRAPPAELSMAPPPPRSVSQETFRISTRKHSNLITVPIQDDSNSGAREPP 309
P + + P PPPR E P Q + S + P
Sbjct: 91 GPPPRPGKPEGQPPQGGNQSQGPPPRPGKPEG-------------PPPQGGNQS---QGP 134
Query: 310 PPAPAPAHHHPEYQGQPVVSHPHHIMPPQQHYAPPPPPPPPISHPMPHPPQAAGTPHLVY 369
PP P P G P P+ PPP P PHP + G P
Sbjct: 135 PPRPGKPEGPPPQGGNQSQGPPPRPGKPE---GPPPQGGNQSQGPPPHPGKPEGPPPQGG 191
Query: 370 SQAPPPPMTSAPPPITPPPGHIIAQMPPYMNHPPPGPP--PPQHGGPPVTAPPPHHYNPN 427
+Q+ PP P PP G +Q PP P PG P PP GG PPPH P
Sbjct: 192 NQSQGPPPRPGKPEGPPPQGGNQSQGPP----PRPGKPEGPPSQGGNKPQGPPPHPGKPQ 247
Query: 428 SLPQFTEDQGTLSPPFTQPGGMSP-GIWPAPRGPPPPPRLQGPPSQTPLPGPHHPDQ 483
P ++ PP +P G P G P PPP + QGPP PH P Q
Sbjct: 248 GPPPQEGNKPQRPPPPGRPQGPPPPGGNPQQPLPPPAGKPQGPPPPPQGGRPHRPPQ 304
Score = 72.8 bits (177), Expect = 7e-13
Identities = 66/214 (30%), Positives = 82/214 (38%), Gaps = 35/214 (16%)
Query: 302 NSGAREPPPPAPAPAHHHPEYQGQPVVSHPHHIMPPQQHYAPPPPPPPPISH---PMPHP 358
N R PPPP +G+P PP + P PPP + P P P
Sbjct: 45 NQPQRTPPPPGKP--------EGRPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRP 96
Query: 359 PQAAGTPHLVYSQAPPPPMTSAPPPITPPPGHIIAQMPPYMNHPPPGPPP---------- 408
+ G P +Q+ PP P PP G +Q PP P GPPP
Sbjct: 97 GKPEGQPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPP 156
Query: 409 PQHG---GPP------VTAPPPHHYNPNSLPQFTEDQGTLSPPFT-QPGGMSPGIWPAPR 458
P+ G GPP PPPH P P +Q PP +P G P +
Sbjct: 157 PRPGKPEGPPPQGGNQSQGPPPHPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQ 216
Query: 459 GPPP-PPRLQGPPSQ---TPLPGPHHPDQTRYRP 488
GPPP P + +GPPSQ P P HP + + P
Sbjct: 217 GPPPRPGKPEGPPSQGGNKPQGPPPHPGKPQGPP 250
Score = 65.1 bits (157), Expect = 1e-10
Identities = 68/239 (28%), Positives = 80/239 (33%), Gaps = 34/239 (14%)
Query: 192 RAGKPV---TRASLENVHPPIAPPPTEIPERFIMPPDKHHMSHIPPKQHIMMPPPPLQHV 248
R GKP + ++ PP P E P PP + S PP + PP Q
Sbjct: 95 RPGKPEGQPPQGGNQSQGPPPRPGKPEGP-----PPQGGNQSQGPPPRPGKPEGPPPQG- 148
Query: 249 PHEHYNQPHEDIRAPPAELSMAPPPPRSVSQETFRISTRKHSNLITVPIQDDSNSGAREP 308
++ PP PPP+ +Q H P N P
Sbjct: 149 -------GNQSQGPPPRPGKPEGPPPQGGNQSQ---GPPPHPGKPEGPPPQGGNQSQGPP 198
Query: 309 P----PPAPAPAHHHPEYQGQPVVSHPHHIMPPQQHYAPPPPPPPPISHPMPHPPQAAGT 364
P P P P + P P PP Q P PPP P PPQ
Sbjct: 199 PRPGKPEGPPPQGGNQSQGPPPRPGKPEG--PPSQGGNKPQGPPPHPGKPQGPPPQEGNK 256
Query: 365 PHLVYSQAPPPPMTSAPPPITPPPGHIIAQMPPYMNHPPPGPPPPQHGGP--PVTAPPP 421
P Q PPPP PP PP G+ +PP P PPPPQ G P P PP
Sbjct: 257 P-----QRPPPPGRPQGPP--PPGGNPQQPLPPPAGKPQGPPPPPQGGRPHRPPQGQPP 308
Score = 51.2 bits (121), Expect = 2e-06
Identities = 44/124 (35%), Positives = 51/124 (41%), Gaps = 16/124 (12%)
Query: 370 SQAPPPPMTSAPPPITPPPGHIIAQMPPYMNHPPPGPP---PPQHGGPPVTAPPPHHYNP 426
SQ P + S P P G Q P PPPG P PPQ GG PPP P
Sbjct: 24 SQEESPSVISGKPEGRRPQGGNQPQRTP----PPPGKPEGRPPQ-GGNQSQGPPPRPGKP 78
Query: 427 NSLPQFTEDQGTLSPPFT-QPGGMSPGIWPAPRGPPP-PPRLQGPP------SQTPLPGP 478
P +Q PP +P G P +GPPP P + +GPP SQ P P P
Sbjct: 79 EGPPPQGGNQSQGPPPRPGKPEGQPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRP 138
Query: 479 HHPD 482
P+
Sbjct: 139 GKPE 142
>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
tract binding protein associated) [Homo sapiens]
Length = 707
Score = 88.6 bits (218), Expect = 1e-17
Identities = 64/177 (36%), Positives = 70/177 (39%), Gaps = 28/177 (15%)
Query: 304 GAREPPPPAPAPAHHHPEYQGQPVVSHPHHIMPPQQHYAPPPPPPPPISHPMPHPPQAAG 363
G P PP P P H + Q QP P PPQQ PPP PP HP PH Q
Sbjct: 52 GQSGPKPPIPPPPPH--QQQQQPPPQQP----PPQQ----PPPHQPP-PHPQPHQQQ--- 97
Query: 364 TPHLVYSQAPPPPMTSAPPPITPPPGHI--IAQMPPYMNHPPPGPPPPQHGGPPVTAPPP 421
Q PPPP S+ P + PG + PP + PP PP G PP + P P
Sbjct: 98 -------QPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTS-GAPPGSGPGP 149
Query: 422 HHYNPNSLPQFTEDQGTLSPPFTQPGGMSPGIWPAPRGPPPPPRLQGPPSQTPLPGP 478
P P T PP T P P P GPPPPP P P GP
Sbjct: 150 ---TPTPPPAVTSAPPGAPPP-TPPSSGVPTTPPQAGGPPPPPAAVPGPGPGPKQGP 202
Score = 78.6 bits (192), Expect = 1e-14
Identities = 76/270 (28%), Positives = 87/270 (32%), Gaps = 54/270 (20%)
Query: 208 PIAPPPTEI-PERFIMPPDKHHMSHIPPKQHIMMPPPPLQHVPHEHYNQPHEDIRAPPAE 266
P+ P P + P+ I PP H PP Q PPP Q PH+ P P +
Sbjct: 46 PMGPGPGQSGPKPPIPPPPPHQQQQQPPPQQ----PPPQQPPPHQPPPHPQ------PHQ 95
Query: 267 LSMAPPPPRSVSQETFRISTRKHSNLITVPIQDDSNSGAREPPPPAPAPAHHHPEYQGQP 326
PPPP QD S + P PAP P P
Sbjct: 96 QQQPPPPP-----------------------QDSSKPVVAQGPGPAPGVGSAPPASSSAP 132
Query: 327 VVSHPHHIMPPQQHYAPPPPPPPPISHPMPHPPQAAGTPHLVYSQAPPPPMTSAPPPITP 386
+ P PP P P PPP ++ P APPP S+ P TP
Sbjct: 133 PATPPTSGAPPGSGPGPTPTPPPAVTSAPP--------------GAPPPTPPSSGVPTTP 178
Query: 387 PPGHIIAQMPPYMNHPPPGPPPPQHGGP--PVTAPPPHHYNPNSLPQFTEDQGTLSPPFT 444
P PP P PGP P Q GP P P P P + G PP
Sbjct: 179 PQAG--GPPPPPAAVPGPGPGPKQGPGPGGPKGGKMPGGPKPGGGPGLSTPGGHPKPP-- 234
Query: 445 QPGGMSPGIWPAPRGPPPPPRLQGPPSQTP 474
GG P P QGPP P
Sbjct: 235 HRGGGEPRGGRQHHPPYHQQHHQGPPPGGP 264
Score = 67.4 bits (163), Expect = 3e-11
Identities = 46/142 (32%), Positives = 52/142 (36%), Gaps = 17/142 (11%)
Query: 353 HPMPHPPQAAGTPHLVYSQAPPPPMTSAPPPITPPPGHIIAQMPPYMNHPPPGPP---PP 409
H PP G P P + PPI PPP H Q PP PP PP PP
Sbjct: 29 HDFRSPPPGMGLNQNRGPMGPGPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQPP 88
Query: 410 QHGGPPVTAPPPHHYNPNSLPQFTEDQG------------TLSPPFTQP-GGMSPGIWPA 456
H P PP +S P + G + +PP T P G PG P
Sbjct: 89 PHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPGSGPG 148
Query: 457 PRGPPPPPRLQGPPSQTPLPGP 478
P P PPP + P P P P
Sbjct: 149 PT-PTPPPAVTSAPPGAPPPTP 169
Score = 32.0 bits (71), Expect = 1.3
Identities = 20/42 (47%), Positives = 21/42 (50%), Gaps = 6/42 (14%)
Query: 446 PGGMSPG-IWPAPRGPPPPP--RLQGPPSQTP---LPGPHHP 481
P G PG P P PPPPP + Q PP Q P P PH P
Sbjct: 46 PMGPGPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQP 87
>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
Length = 416
Score = 88.2 bits (217), Expect = 2e-17
Identities = 88/283 (31%), Positives = 103/283 (36%), Gaps = 38/283 (13%)
Query: 208 PIAPPPTEIPERFIMPPDKHHMSHIPPKQHIMMPPPPLQHVPHEHYNQPHEDIRAPPAEL 267
P PPP P+ PP + S P PP Q P + NQP PP
Sbjct: 89 PQGPPPPGKPQG---PPPQGDKSRSPRS-----PPGKPQGPPPQGGNQPQGP---PPPPG 137
Query: 268 SMAPPPPRSVSQETFRISTRKHSNLITVPIQDDSNSGAREPPPPAPA--PAHHHPEYQGQ 325
PPP+ ++ K P Q D+ S + PP P P + QG
Sbjct: 138 KPQGPPPQGGNKPQGPPPPGKPQG---PPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGP 194
Query: 326 PVVSHPHHIMPPQQHYAPPPPPPPPISHPMPHPPQAAGTPHLVYS-----QAPPPPMTSA 380
P PPQ P PPPP P PPQ S Q PPP +
Sbjct: 195 PPPPGKPQGPPPQGGNKPQGPPPP--GKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQ 252
Query: 381 PPPITPPPGHIIAQMPPYMNHPPPGPPPPQHGGPPVTAPPP------HHYNPNSLPQFTE 434
P PPPG PP + P GPPPP G P PP +P PQ
Sbjct: 253 PQGPPPPPGKPQGP-PPQGGNKPQGPPPP---GKPQGPPPQGGSKSRSSRSPPGKPQGPP 308
Query: 435 DQGTLSP-----PFTQPGGMSPGIWPAPRGPPPPPRLQGPPSQ 472
QG P P +P G P P+GPPPP + QGPP Q
Sbjct: 309 PQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQ 351
Score = 81.3 bits (199), Expect = 2e-15
Identities = 88/300 (29%), Positives = 100/300 (33%), Gaps = 44/300 (14%)
Query: 194 GKPVTRASLENVHPPIAPPPTEIPERFIMPPDKHHMSHIPPKQHIMMPPPPLQHVPHEHY 253
GKP P PPP P+ PP + PP PPP
Sbjct: 55 GKPQGPPPQGGNQPQGPPPPPGKPQG--PPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPR 112
Query: 254 NQPHEDIRAPP--AELSMAPPPPRSVSQETFRISTRKHSNLITVPIQDDSNSGAREPPPP 311
+ P + PP PPPP Q P N PPP
Sbjct: 113 SPPGKPQGPPPQGGNQPQGPPPPPGKPQG---------------PPPQGGNKPQGPPPPG 157
Query: 312 APAPAHHHPEYQGQPVVSHPHHIM-PPQQHYAPPPPPPPPISHPMPHPPQAAGTPHLVYS 370
P + + + S P PP Q P PPPP P PPQ P
Sbjct: 158 KPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKP----- 212
Query: 371 QAPPPPMTSAPPPITPPPGHIIAQMPPY--MNHPPPGPPPPQHGGPP---VTAPPPHHYN 425
Q PPPP PP A+ PP PP G PQ PP PPP N
Sbjct: 213 QGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGN 272
Query: 426 ------PNSLPQFTEDQG------TLSPPFTQPGGMSPGIWPAPRGPPPPP-RLQGPPSQ 472
P PQ QG + SPP +P G P P+GPPPPP + QGPP Q
Sbjct: 273 KPQGPPPPGKPQGPPPQGGSKSRSSRSPP-GKPQGPPPQGGNQPQGPPPPPGKPQGPPPQ 331
Score = 75.5 bits (184), Expect = 1e-13
Identities = 89/316 (28%), Positives = 101/316 (31%), Gaps = 50/316 (15%)
Query: 194 GKPVTRASLENVHPPIAPPPTEIPERFIMPPDKHHMSHIPPKQHIMMPPPPLQHVPHEHY 253
GKP P PPP P+ PP + PP PPP
Sbjct: 116 GKPQGPPPQGGNQPQGPPPPPGKPQG--PPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSS 173
Query: 254 NQPHEDIRAPPAE---LSMAPPPPRSVSQETFRISTRKHSNLITVPIQDDSNSGAREPPP 310
P + PP + PPPP Q P N PPP
Sbjct: 174 RSPPGKPQGPPPQGGNQPQGPPPPPGKPQG---------------PPPQGGNKPQGPPPP 218
Query: 311 PAPAPAHHHPEYQGQPVVSHPHHIM-PPQQHYAPPPPPPPPISHPMPHPPQAAGTPHLVY 369
P + + Q S P PP Q P PPPP P PPQ P
Sbjct: 219 GKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKP---- 274
Query: 370 SQAPPPPMTSAPPPITPPPGHIIAQMPPY--MNHPPPGPPPPQHGGPP---VTAPPPHHY 424
Q PPPP PP ++ PP PP G PQ PP PPP
Sbjct: 275 -QGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGG 333
Query: 425 N------PNSLPQFTEDQG------TLSPPFTQPGGMSPGIWPAPRGPPP-----PPRLQ 467
N P PQ QG SPP +P G P+GPPP P + Q
Sbjct: 334 NKPQGPPPPGKPQGPPPQGGSKSRSARSPP-GKPQGPPQQEGNNPQGPPPPAGGNPQQPQ 392
Query: 468 GPPSQTPLPGPHHPDQ 483
PP+ P GP P Q
Sbjct: 393 APPAGQP-QGPPRPPQ 407
Score = 72.8 bits (177), Expect = 7e-13
Identities = 69/215 (32%), Positives = 81/215 (37%), Gaps = 36/215 (16%)
Query: 284 ISTRKHSNLITVPIQDDSNSGAREPP-PPAPAPAHHHPEYQG--QPVVSHPHHIMPPQQH 340
+S + +LI Q G +P PP+P P QG QP P PP +
Sbjct: 23 VSQEESPSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPP----PPGKP 78
Query: 341 YAPPPPP------PPPISHPMPHPPQA---------AGTPHLVYSQAPPPPMTSAPPPIT 385
PPP PPP P PPQ G P Q PPP + P
Sbjct: 79 QGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKP-----QGPPPQGGNQPQGPP 133
Query: 386 PPPGHIIAQMPPYMNHPPPGPPP---PQHGGPPVTAPPPHHYNPNSLPQFTEDQGTLS-- 440
PPPG PP + P GPPP PQ P +P PQ QG
Sbjct: 134 PPPGKPQGP-PPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQ 192
Query: 441 ---PPFTQPGGMSPGIWPAPRGPPPPPRLQGPPSQ 472
PP +P G P P+GPPPP + QGPP Q
Sbjct: 193 GPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQ 227
Score = 66.2 bits (160), Expect = 6e-11
Identities = 87/315 (27%), Positives = 99/315 (31%), Gaps = 97/315 (30%)
Query: 208 PIAPPPTEIPERFIMPP----DKHHMSHIPP-----------KQHIMMPPPP--LQHVPH 250
P PPP P+ PP +K S PP Q PPPP Q P
Sbjct: 150 PQGPPPPGKPQG---PPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPP 206
Query: 251 EHYNQPHEDIRAPPAELSMAPPPPRSVSQETFRISTRKHSNLITVPIQDDSNSGAREPPP 310
+ N+P PP PPP ++ R K P N PPP
Sbjct: 207 QGGNKPQGP---PPPGKPQGPPPQGDNKSQSARSPPGKPQG----PPPQGGNQPQGPPPP 259
Query: 311 PAPA---PAHHHPEYQGQPVVSHPH------------HIMPPQQHYAPPPP-------PP 348
P P + QG P P PP + PPP PP
Sbjct: 260 PGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPP 319
Query: 349 PPISHPMPHPPQAAGTPHLVYSQAPPPP-MTSAPPP--------ITPPPGHIIAQMPPYM 399
PP P PPQ P Q PPPP PPP PPG Q PP
Sbjct: 320 PPPGKPQGPPPQGGNKP-----QGPPPPGKPQGPPPQGGSKSRSARSPPGK--PQGPPQQ 372
Query: 400 NHPPPGPPPPQHGGPPVTAPPPHHYNPNSLPQFTEDQGTLSPPFTQPGGMSPGIWPAPRG 459
P PPP GG P Q +PP Q P+G
Sbjct: 373 EGNNPQGPPPPAGGNP--------------------QQPQAPPAGQ-----------PQG 401
Query: 460 PPPPPRLQGPPSQTP 474
PP PP+ G PS+ P
Sbjct: 402 PPRPPQ-GGRPSRPP 415
>gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens]
Length = 424
Score = 87.0 bits (214), Expect = 3e-17
Identities = 67/182 (36%), Positives = 70/182 (38%), Gaps = 28/182 (15%)
Query: 305 AREPPPPAPAPAHHHPEYQGQPVVSHPHHIMPPQQHYAPPPPPPPPISHP-------MPH 357
A PPP P A H P G P HP H H P P PP + HP H
Sbjct: 260 AMPPPPMPPGAAGHGPPSAGTPGAGHPGH-----GHSHPHPFPPGGMPHPGMSQMQLAHH 314
Query: 358 PPQAAGTPHLVYSQAPPPPMTSAPPPITPPPGHIIAQMPPYMNHPPPGPP---PPQHGGP 414
P G PH A PP PPP PPPG + PP M PP GPP P H GP
Sbjct: 315 GPHGLGHPH-----AGPPGSGGQPPP-RPPPG-MPHPGPPPMGMPPRGPPFGSPMGHPGP 367
Query: 415 PVTAPPPHHYNPNSLPQFTEDQGTLSPPFTQPGGMSPGIWPAPRGPPPPPRLQGPPSQTP 474
PPH P G PP P G G P PR P PP P + P
Sbjct: 368 ----MPPH--GMRGPPPLMPPHGYTGPPRPPPYGYQRGPLPPPRPTPRPPVPPRGPLRGP 421
Query: 475 LP 476
LP
Sbjct: 422 LP 423
Score = 80.9 bits (198), Expect = 2e-15
Identities = 87/283 (30%), Positives = 98/283 (34%), Gaps = 81/283 (28%)
Query: 193 AGKPVTRASLENVHPPIAPPPTEIPERFIMPPDKHHMSHIPPKQHIMMPPPPLQHVPHEH 252
A PV + + PP PPP P +PP IPP MPPPP+
Sbjct: 220 APNPVVSSLGSGLPPPGMPPPGSFPPP--VPPPGALPPGIPP----AMPPPPM------- 266
Query: 253 YNQPHEDIRAPPAELSMAPPPPRSVSQETFRISTRKHSNLITVPIQDDSNSGAREPPPPA 312
PP PP S HS+ P G P
Sbjct: 267 ----------PPGAAGHGPP---SAGTPGAGHPGHGHSHPHPFP-----PGGMPHPGMSQ 308
Query: 313 PAPAHHHPEYQGQPVVSHPHHIMPPQQHYAPPPPPPPPISHPMPHPPQAAGTPHLVYSQA 372
AHH P G P H PP PPP PPP + HP P
Sbjct: 309 MQLAHHGPHGLGHP------HAGPPGSGGQPPPRPPPGMPHPGP---------------- 346
Query: 373 PPPPMTSAPPPITPPPGHIIAQMPPY-MNHPPPGPPPPQHGGPPVTAPPPHHYNPNSLPQ 431
PP M PP P GH MPP+ M PPP PP + GPP PPP+ Y
Sbjct: 347 PPMGMPPRGPPFGSPMGH-PGPMPPHGMRGPPPLMPPHGYTGPP--RPPPYGY------- 396
Query: 432 FTEDQGTLSPPFTQPGGMSPGIWPAPRGPPPPPR--LQGPPSQ 472
+G L PP P PR PP PPR L+GP Q
Sbjct: 397 ---QRGPLPPP-----------RPTPR-PPVPPRGPLRGPLPQ 424
Score = 75.1 bits (183), Expect = 1e-13
Identities = 72/204 (35%), Positives = 83/204 (40%), Gaps = 41/204 (20%)
Query: 301 SNSGAREPPPPAPAPAHHHPEYQGQPVVSHPHHIMPPQQHYAPPPPPPPPISHPMPHPPQ 360
S+ G+ PPP P P P PV P +PP A PPPP PP + H P
Sbjct: 226 SSLGSGLPPPGMPPPGSFPP-----PVP--PPGALPPGIPPAMPPPPMPPGA--AGHGPP 276
Query: 361 AAGTP---HLVYSQAPPPPMTSAPPPITPPPGHIIAQM----PPYMNHPPPGPPPPQHGG 413
+AGTP H + + P P PP P PG Q+ P + HP GPP GG
Sbjct: 277 SAGTPGAGHPGHGHSHPHPF---PPGGMPHPGMSQMQLAHHGPHGLGHPHAGPPGS--GG 331
Query: 414 PPVTAPPPHHYNPNSLPQFTEDQGTLSPPFTQPGGMSPGIWP--APRGPPP--------- 462
P PPP +P P +G PPF P G PG P RGPPP
Sbjct: 332 QPPPRPPPGMPHPGPPPMGMPPRG---PPFGSPMG-HPGPMPPHGMRGPPPLMPPHGYTG 387
Query: 463 PPR-----LQGPPSQTPLPGPHHP 481
PPR Q P P P P P
Sbjct: 388 PPRPPPYGYQRGPLPPPRPTPRPP 411
Score = 70.5 bits (171), Expect = 3e-12
Identities = 68/215 (31%), Positives = 79/215 (36%), Gaps = 40/215 (18%)
Query: 310 PPAPAPAHHHPEYQGQPVVSHPHHIMPPQQHYAPPPPPPPPISHPMPHPPQAAGTPHLVY 369
P + A H P S P+ ++ PPP PPP S P P PP A P +
Sbjct: 200 PLSQADRPHQLFADAPPPPSAPNPVVSSLGSGLPPPGMPPPGSFPPPVPPPGALPPGIPP 259
Query: 370 SQAPPPPMTSA----PPPITPP----PGHIIAQMPPY----MNHP--------------- 402
+ PPP A PP P PGH + P+ M HP
Sbjct: 260 AMPPPPMPPGAAGHGPPSAGTPGAGHPGHGHSHPHPFPPGGMPHPGMSQMQLAHHGPHGL 319
Query: 403 -PPGPPPPQHGGPPVTAPPPHHYNPNSLPQFTEDQGTLSPPFTQPGGMSPGIWP--APRG 459
P PP GG P PPP +P P +G PPF P G PG P RG
Sbjct: 320 GHPHAGPPGSGGQPPPRPPPGMPHPGPPPMGMPPRG---PPFGSPMG-HPGPMPPHGMRG 375
Query: 460 PP---PPPRLQGPPSQTPL---PGPHHPDQTRYRP 488
PP PP GPP P GP P + RP
Sbjct: 376 PPPLMPPHGYTGPPRPPPYGYQRGPLPPPRPTPRP 410
Score = 65.1 bits (157), Expect = 1e-10
Identities = 55/186 (29%), Positives = 66/186 (35%), Gaps = 61/186 (32%)
Query: 357 HPPQAAGTPHLVYSQAPPPPMTSAP--------------------PPITPPPGHIIAQMP 396
+P A PH +++ APPPP P PP PPPG + +P
Sbjct: 199 NPLSQADRPHQLFADAPPPPSAPNPVVSSLGSGLPPPGMPPPGSFPPPVPPPGALPPGIP 258
Query: 397 PYMNHPPPGPPPPQHGGPPVTAPP-----------PHHYNPNSLPQFTEDQ--------- 436
P M PPP PP GPP P PH + P +P Q
Sbjct: 259 PAM-PPPPMPPGAAGHGPPSAGTPGAGHPGHGHSHPHPFPPGGMPHPGMSQMQLAHHGPH 317
Query: 437 ------------GTLSPPFTQPGGMSPGIWPAPRGPPPPPRLQGPPSQTPL--PGPHHPD 482
G PP PG PG P P G PP +GPP +P+ PGP P
Sbjct: 318 GLGHPHAGPPGSGGQPPPRPPPGMPHPG--PPPMGMPP----RGPPFGSPMGHPGPMPPH 371
Query: 483 QTRYRP 488
R P
Sbjct: 372 GMRGPP 377
>gi|11386183 WAS protein family, member 2 [Homo sapiens]
Length = 498
Score = 85.5 bits (210), Expect = 1e-16
Identities = 76/230 (33%), Positives = 87/230 (37%), Gaps = 69/230 (30%)
Query: 266 ELSMAPPPPRSVSQETFRISTRKHSNL------ITVPIQDDSNSGAREP----------P 309
+ S PPPP+S S + S + NL + P+ + SG P P
Sbjct: 242 DASSYPPPPQSDSASSPSPSFSE-DNLPPPPAEFSYPVDNQRGSGLAGPKRSSVVSPSHP 300
Query: 310 PPAPAPAHHHPEYQGQPVVSHPHHIMPPQQHYAPPPPPPPPISHPMPHPPQAAGTPHLVY 369
PPAP G P P PP APPPPPPP I P P PP G+P
Sbjct: 301 PPAPP--------LGSPPGPKPGFAPPP----APPPPPPPMIGIPPPPPPVGFGSPG--- 345
Query: 370 SQAPPPPMTSAPPPITPPPGHIIAQMPPYMNHPPPGPPPPQHGGPPVTAPPPHHYNPNSL 429
PPPP PP PP A PPP PPPP P T PP
Sbjct: 346 --TPPPPS----PPSFPPHPDFAA--------PPPPPPPPAADYP--TLPP--------- 380
Query: 430 PQFTEDQGTLSPPFTQPGGMSPGIWPAPRGP-PPPPRLQGPPSQTPLPGP 478
PP +QP G +P P P P PPPP G Q +P P
Sbjct: 381 -----------PPLSQPTGGAPPPPPPPPPPGPPPPPFTGADGQPAIPPP 419
Score = 68.6 bits (166), Expect = 1e-11
Identities = 65/243 (26%), Positives = 81/243 (33%), Gaps = 93/243 (38%)
Query: 193 AGKPVTRASLENVHPPIAPPPTEIPERFIMPPDKHHMSHI--PPKQHIMMP--PPPLQHV 248
A P S +N+ PP P F P D S + P + ++ P PPP +
Sbjct: 255 ASSPSPSFSEDNLPPP--------PAEFSYPVDNQRGSGLAGPKRSSVVSPSHPPPAPPL 306
Query: 249 -----PHEHYNQPHEDIRAPPAELSMAPPPPRSVSQETFRISTRKHSNLITVPIQDDSNS 303
P + P PP + + PPPP P+ S
Sbjct: 307 GSPPGPKPGFAPPPAPPPPPPPMIGIPPPPP---------------------PVGFGSPG 345
Query: 304 GAREPPPPAPAPAHHHPEYQGQPVVSHPHHIMPPQQHYAPPPPPPPPISHPMPHPPQAAG 363
PPPP+P HP++ APPPPPPPP +
Sbjct: 346 ---TPPPPSPPSFPPHPDFA------------------APPPPPPPPAAD---------- 374
Query: 364 TPHLVYSQAPPPPM---TSAPPPITPPPGHIIAQMPPYMNHPPPGPPPPQH---GGPPVT 417
Y PPPP+ T PP PPP PPPGPPPP G P
Sbjct: 375 -----YPTLPPPPLSQPTGGAPPPPPPP-------------PPPGPPPPPFTGADGQPAI 416
Query: 418 APP 420
PP
Sbjct: 417 PPP 419
Score = 54.7 bits (130), Expect = 2e-07
Identities = 46/140 (32%), Positives = 54/140 (38%), Gaps = 34/140 (24%)
Query: 345 PPPPPPISHPMPHPPQA--AGTPHL-VYSQAPPPPMTSAPPPITPPPGHIIAQMPPYMNH 401
PPPP S+P+ + + AG V S + PPP PP+ PPG PP
Sbjct: 268 PPPPAEFSYPVDNQRGSGLAGPKRSSVVSPSHPPPA----PPLGSPPGPKPGFAPP---P 320
Query: 402 PPPGPPPPQHGGPPVTAPPPHHYNPNSLPQFTEDQGTLSPPFTQPGGMSPGIWPAPRGPP 461
PP PPPP G PP PPP F PG P P+P P
Sbjct: 321 APPPPPPPMIGIPP---PPP------------------PVGFGSPGTPPP---PSPPSFP 356
Query: 462 PPPRLQGPPSQTPLPGPHHP 481
P P PP P P +P
Sbjct: 357 PHPDFAAPPPPPPPPAADYP 376
>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
sapiens]
Length = 1362
Score = 85.1 bits (209), Expect = 1e-16
Identities = 90/340 (26%), Positives = 117/340 (34%), Gaps = 48/340 (14%)
Query: 180 RDLQAHINHRHMR---AGKPVTRASLENVHPPIAPPPTEIPERFIMPPDKHHMSHIPPKQ 236
R+ + H +H H + A PV + P PPP + ++ PP M
Sbjct: 733 REQKKHHHHHHQQMQQAPAPVPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPA 792
Query: 237 HIMMPPPPLQ--------------HVPHEHYNQPHEDIRAPPAELSMAPPP----PRSVS 278
PPP + P H+ QP + P + PP P ++
Sbjct: 793 MKSSPPPFIATQVPVLEPQLPGSVFDPIGHFTQPILHLPQPELPPHLPQPPEHSTPPHLN 852
Query: 279 QETFRISTRKHSNLITVPIQDDSNSGAREPPPPAPAPAHHHPEYQGQPVVSHPHHIMPPQ 338
Q H+ L P + SN A PP PA PA P P++ P PPQ
Sbjct: 853 QHAVVSPPALHNALPQQPSR-PSNRAAALPPKPARPPA-VSPALTQTPLLPQPPMAQPPQ 910
Query: 339 QHYAPPPPPPPPISHPMPH---------PPQAAGTPHLVYSQAPPPPMTSAPPPITPPPG 389
PP PP++ P P + PPPP+ PPP P
Sbjct: 911 VLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPL---PPPPHPSVQ 967
Query: 390 HIIAQMPPYMNHPPPGPPPPQHGGPPVTAPPPHHYNPNSLPQFTEDQGTLSPPFTQPGGM 449
+ Q PP P P PPP Q PP P P H P + PP P G
Sbjct: 968 QQLQQQPPPPPPPQPQPPPQQQHQPP---PRPVHLQPMQFSTHIQ-----QPP--PPQGQ 1017
Query: 450 SPGIWPAPRGPPPPPRLQGPPSQTPLPGPHHPDQTRYRPY 489
P P P PPPP+ P Q + H P + PY
Sbjct: 1018 QPP-HPPPGQQPPPPQPAKP--QQVIQHHHSPRHHKSDPY 1054
Score = 72.0 bits (175), Expect = 1e-12
Identities = 63/205 (30%), Positives = 73/205 (35%), Gaps = 54/205 (26%)
Query: 300 DSNSGAREPPPPAPAPAHHHPEYQGQPVVSHPHHIMPPQQHYAPPP--PPPPPISHPMPH 357
DS E P + H E + H HH QQ AP P PPPPP P P
Sbjct: 713 DSEDSETEMAPKSKKKGHPGREQKKH----HHHHHQQMQQAPAPVPQQPPPPPQQPPPPP 768
Query: 358 PPQAAGTPHLVYSQAPPPPMTSAPPPITP-----PPGHIIAQMP---------------- 396
PPQ P PPPP S P P PP I Q+P
Sbjct: 769 PPQQQQQP------PPPPPPPSMPQQAAPAMKSSPPPFIATQVPVLEPQLPGSVFDPIGH 822
Query: 397 --------PYMNHPPPGPPPPQHGGPP------VTAPPPHHYNPNSLPQF----TEDQGT 438
P PP P PP+H PP V +PP H N+LPQ +
Sbjct: 823 FTQPILHLPQPELPPHLPQPPEHSTPPHLNQHAVVSPPALH---NALPQQPSRPSNRAAA 879
Query: 439 LSPPFTQPGGMSPGIWPAPRGPPPP 463
L P +P +SP + P P PP
Sbjct: 880 LPPKPARPPAVSPALTQTPLLPQPP 904
Score = 58.9 bits (141), Expect = 1e-08
Identities = 78/328 (23%), Positives = 108/328 (32%), Gaps = 61/328 (18%)
Query: 207 PPIAPPPTEIPERFIMPPDKHHMSHIPPKQHIMMPPPPLQHVPHEHYNQPHEDIRA---- 262
P + P E+P PP+ H+ QH ++ PP L + + ++P A
Sbjct: 826 PILHLPQPELPPHLPQPPEHSTPPHL--NQHAVVSPPALHNALPQQPSRPSNRAAALPPK 883
Query: 263 ---PPA------ELSMAPPPPRSVSQETFRIS--------TRKHSNLITVPIQD------ 299
PPA + + P PP + + T L +Q
Sbjct: 884 PARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTP 943
Query: 300 --DSNSGAREPPPPAPAPAHHHPEYQGQ---PVVSHPHHIMPPQQHYAPPPPP----PPP 350
S +PPPP P P H + Q Q P P PPQQ + PPP P P
Sbjct: 944 LLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPPRPVHLQPMQ 1003
Query: 351 ISHPMPHPPQAAGTPHLVYSQAPPPPMTSAPPPITPPPGHIIAQMPPYMNHPPPGPPPPQ 410
S + PP G Q P PP PPP P + Q + + P P
Sbjct: 1004 FSTHIQQPPPPQG------QQPPHPPPGQQPPPPQPAKPQQVIQ---HHHSPRHHKSDPY 1054
Query: 411 HGGPPVTAPPPHHYNPNSLPQFTEDQGTLSP-----PFTQPGGMSPGIWPAPRGPPPPPR 465
G AP P + + QF P P Q + + P P +
Sbjct: 1055 STGHLREAPSPLMIHSPQMSQFQSLTHQSPPQQNVQPKKQELRAASVVQPQPLVVVKEEK 1114
Query: 466 LQGP--------PSQTPLPGPHHPDQTR 485
+ P PS P P P HP+ +
Sbjct: 1115 IHSPIIRSEPFSPSLRPEP-PKHPESIK 1141
Score = 53.9 bits (128), Expect = 3e-07
Identities = 49/162 (30%), Positives = 60/162 (37%), Gaps = 27/162 (16%)
Query: 324 GQPVVSHPHHIMPPQQHYAPPPPPPPPISHPMPHPPQAAGTPHLVYSQAPPPPMTSAPP- 382
G V + P Q P P PPP + P P P A TP L+ P MT PP
Sbjct: 192 GVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFP---AVTPDLI---VQTPVMTVVPPQ 245
Query: 383 PI-TPPPGHIIAQMPPYMNHPPPGPPPPQHGGPPVTAPPPHHYNPNSLPQFTEDQGTLSP 441
P+ TPPP +PP PP P P PP+ A P + D T +P
Sbjct: 246 PLQTPPP------VPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKAD--TTTP 297
Query: 442 PFTQPGGMSPGIWPAPR-----------GPPPPPRLQGPPSQ 472
P P + P P+ P PP+ P SQ
Sbjct: 298 TTIDPIHEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDSQ 339
Score = 52.4 bits (124), Expect = 9e-07
Identities = 66/268 (24%), Positives = 82/268 (30%), Gaps = 67/268 (25%)
Query: 202 LENVHPPIAPPPTEIPERF-------IMPPDKHHMSHIPPKQHIMMPPPPLQHVPHEHYN 254
LE+ PP APP T + + + PP +P + PPPPL PH
Sbjct: 913 LEDEEPP-APPLTSMQMQLYLQQLQKVQPPTPL----LPSVKVQSQPPPPLPPPPHPSVQ 967
Query: 255 QPHEDIRAPPAELSMAPPP-------PRSVSQETFRISTRKHSNLITVPIQDDSNSGARE 307
Q + PP PPP PR V + + ST Q ++
Sbjct: 968 QQLQQQPPPPPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPPGQQ 1027
Query: 308 PPPPAPAPA------HHHPEYQGQPVVSHPH----------------------HIMPPQQ 339
PPPP PA HH P + S H H PPQQ
Sbjct: 1028 PPPPQPAKPQQVIQHHHSPRHHKSDPYSTGHLREAPSPLMIHSPQMSQFQSLTHQSPPQQ 1087
Query: 340 HYAPP-----------PPPPPPISHPMPHPPQAAGTPHLVYSQAPPPP---MTSAP---- 381
+ P P P + H P P + PP AP
Sbjct: 1088 NVQPKKQELRAASVVQPQPLVVVKEEKIHSPIIRSEPFSPSLRPEPPKHPESIKAPVHLP 1147
Query: 382 --PPITPPPGHIIAQMPPYMNHPPPGPP 407
P + P PP N PPPG P
Sbjct: 1148 QRPEMKPVDVGRPVIRPPEQNAPPPGAP 1175
Score = 46.2 bits (108), Expect = 7e-05
Identities = 31/97 (31%), Positives = 36/97 (37%), Gaps = 8/97 (8%)
Query: 309 PPPAPAPAHHHPEYQGQPVVSHPHHIMPPQQHYAPPPPPPP-----PISHPMP---HPPQ 360
PPP A H P +V P + P Q PPP PP P P P HPP
Sbjct: 215 PPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPI 274
Query: 361 AAGTPHLVYSQAPPPPMTSAPPPITPPPGHIIAQMPP 397
A TP V ++ P T P H +PP
Sbjct: 275 IAATPQPVKTKKGVKRKADTTTPTTIDPIHEPPSLPP 311
Score = 43.5 bits (101), Expect = 4e-04
Identities = 31/103 (30%), Positives = 39/103 (37%), Gaps = 18/103 (17%)
Query: 379 SAPPPITPPPGHIIAQMPPYMNHPPPGPPPPQHGGPPVTAPPPHHYNPNSLPQFTEDQGT 438
+A P ++ P A PP P P PPP Q P+ P T D
Sbjct: 188 TAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQ-------------ATPHPFPAVTPDLIV 234
Query: 439 LSPPFTQPGGMSPGIWPAPRGPPPPPRLQGPPSQTPLPGPHHP 481
+P T + P P PP PP+ Q PP+ P P HP
Sbjct: 235 QTPVMTV---VPP--QPLQTPPPVPPQPQPPPAPAPQPVQSHP 272
Score = 40.8 bits (94), Expect = 0.003
Identities = 47/177 (26%), Positives = 66/177 (37%), Gaps = 29/177 (16%)
Query: 206 HPPIA----PPPTEIPERFIMP--PDKHHMSHIPPKQHIMMPPPPLQ-HVPH-------E 251
HPP PP P++ I +HH S H+ P PL H P
Sbjct: 1021 HPPPGQQPPPPQPAKPQQVIQHHHSPRHHKSDPYSTGHLREAPSPLMIHSPQMSQFQSLT 1080
Query: 252 HYNQPHEDIRAPPAEL---SMAPPPPRSVSQETFRISTRKHSNLITVPIQDDSNSGAREP 308
H + P ++++ EL S+ P P V +E + HS +I + + R
Sbjct: 1081 HQSPPQQNVQPKKQELRAASVVQPQPLVVVKEE-----KIHSPIIR---SEPFSPSLRPE 1132
Query: 309 PPPAP----APAHHHPEYQGQPVVSHPHHIMPPQQHYAPPPPPPPPISHPMPHPPQA 361
PP P AP H + +PV I PP+Q+ PP P P P A
Sbjct: 1133 PPKHPESIKAPVHLPQRPEMKPVDVGRPVIRPPEQNAPPPGAPDKDKQKQEPKTPVA 1189
Score = 35.8 bits (81), Expect = 0.091
Identities = 40/180 (22%), Positives = 57/180 (31%), Gaps = 48/180 (26%)
Query: 233 PPKQHIMMP-PPPLQHVPHEHYNQPHEDIRAPPAELSMAPPPPRSVSQETFRISTRKHSN 291
PP+ P PPP+Q PH + D+ +++ PP P
Sbjct: 205 PPQTQTPQPNPPPVQATPHP-FPAVTPDLIVQTPVMTVVPPQPLQTPP------------ 251
Query: 292 LITVPIQDDSNSGAREPPPPAPAPAHHHPEYQGQPVVSHPHHIMPPQQHYAPPPPPPPPI 351
VP Q + PP PAP P HP + + P + + P
Sbjct: 252 --PVPPQ------PQPPPAPAPQPVQSHPPI----IAATPQPVKTKKGVKRKADTTTPTT 299
Query: 352 SHPMPHPPQAAGTPHLVYSQAPPPPMTS-------APPPITPPPGHIIAQMPPYMNHPPP 404
P+ PP PP P T+ + P+ PP +P HP P
Sbjct: 300 IDPIHEPP-----------SLPPEPKTTKLGQRRESSRPVKPPK----KDVPDSQQHPAP 344
>gi|42544130 splicing factor 1 isoform 1 [Homo sapiens]
Length = 639
Score = 85.1 bits (209), Expect = 1e-16
Identities = 63/192 (32%), Positives = 78/192 (40%), Gaps = 22/192 (11%)
Query: 221 IMPPDKHHMSHIPPKQHIMMPPPPLQHVPHEHYNQPHEDIRAPPAELSMAPPPPRSVSQE 280
+MPP M PP PPPP Q + PP SMA P Q
Sbjct: 469 MMPPPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQN 528
Query: 281 TFRISTRKHSNLITVPIQDDSNSGAREPPPPAPAPAHHHPEYQGQP-VVSHPHHIMPPQQ 339
T +T + I P Q + A P P + QG P +V P + PP
Sbjct: 529 TTTTTTSAGTGSIP-PWQQQQAAAAASPGAP---------QMQGNPTMVPLPPGVQPPLP 578
Query: 340 HYAPPPPPPPPISHPMPHPPQAAGTPHLVYSQAPPPPMTSAPPPITPPPGHIIAQMPPYM 399
APPPPPPPP P +AG ++Y+ PPPP P G +A MPP+
Sbjct: 579 PGAPPPPPPPP--------PGSAG---MMYAPPPPPPPPMDPSNFVTMMGMGVAGMPPFG 627
Query: 400 NHPPPGPPPPQH 411
P P PPPPQ+
Sbjct: 628 MPPAPPPPPPQN 639
Score = 79.3 bits (194), Expect = 7e-15
Identities = 73/260 (28%), Positives = 95/260 (36%), Gaps = 58/260 (22%)
Query: 228 HMSHIPPKQHIMMPPPPLQHVPHEHYNQPHEDIRAPPAELSMAPPPPRSVSQETFRISTR 287
H + PP + PPPP+ PH P PP + + P V +R+
Sbjct: 415 HNPNGPPPPWMQPPPPPMNQGPH-----PPGHHGPPPMDQYLGSTP---VGSGVYRLHQG 466
Query: 288 KHSNLITVPIQDDSNSGAREPPPPAPAPAHHHPEYQGQPVVSHPHHIMPPQQHYAPPPPP 347
K + G PPPP P+ GQP + P QQ PPPP
Sbjct: 467 KG-------MMPPPPMGMMPPPPPPPS---------GQPPPPPSGPLPPWQQQQQQPPPP 510
Query: 348 PPPISH-----PMPHPPQ------AAGTPHL--------VYSQAPPPPMTSAPPPITPPP 388
PPP S P+P +AGT + + +P P P + P P
Sbjct: 511 PPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLP 570
Query: 389 GHIIAQMPPYMNHPPPGPPPPQHG---GPPVTAPPPHHYNPNSLPQFTEDQGTLSPPFTQ 445
+ +PP PPP PPP G PP PPP +P++ PPF
Sbjct: 571 PGVQPPLPPGAPPPPPPPPPGSAGMMYAPPPPPPPP--MDPSNFVTMMGMGVAGMPPFGM 628
Query: 446 PGGMSPGIWPAPRGPPPPPR 465
P PAP PPPPP+
Sbjct: 629 P--------PAP--PPPPPQ 638
Score = 76.6 bits (187), Expect = 5e-14
Identities = 85/276 (30%), Positives = 93/276 (33%), Gaps = 73/276 (26%)
Query: 264 PAELSMAPPPPRSVSQETFRISTRKHSNLITVPIQDDSNSGAREPPPPAPAPAHHHPEYQ 323
PA + PPPP +S R + P G P P P H P
Sbjct: 346 PAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMHGGG---PGGPGGGP-HSFPHPL 401
Query: 324 GQPVVSHPHHIMPPQQHY--APPPP---PPPPISHPMPHPPQAAGTP------------- 365
H H P QH PPPP PPPP + PHPP G P
Sbjct: 402 PSLTGGHGGH---PMQHNPNGPPPPWMQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGS 458
Query: 366 -----HLVYSQAPPPPMTSAPPPITPPPGHIIAQMPPYMNHPPPGPPPP--QHGGPPVTA 418
H PPPPM PPP PP G Q PP PP GP PP Q P
Sbjct: 459 GVYRLHQGKGMMPPPPMGMMPPPPPPPSG----QPPP----PPSGPLPPWQQQQQQPPPP 510
Query: 419 PPPHHYNPNSLP--------QFTEDQGTLS-PPFTQ--------PGG-----------MS 450
PPP +S P T GT S PP+ Q PG +
Sbjct: 511 PPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLP 570
Query: 451 PGIWP-----APRGPPPPPRLQGPPSQTPLPGPHHP 481
PG+ P AP PPPPP P P P P
Sbjct: 571 PGVQPPLPPGAPPPPPPPPPGSAGMMYAPPPPPPPP 606
Score = 61.6 bits (148), Expect = 2e-09
Identities = 72/272 (26%), Positives = 88/272 (32%), Gaps = 79/272 (29%)
Query: 265 AELSMAPPPPRSVSQETFRISTRKHSNLITVPIQDDSNSGA--REPPPPA--PAPAHHHP 320
AEL AP P S S T P+ A PPPP+ P
Sbjct: 318 AELGEAPVPA----------SVGSTSGPATTPLASAPRPAAPANNPPPPSLMSTTQSRPP 367
Query: 321 EYQGQPVVSHPHHIMPPQQHYAPP------PPPPPPIS-----HPMPHPPQAAGTPHLVY 369
P S P+H M P P P P ++ HPM H P P +
Sbjct: 368 WMNSGPSESRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPP---W 424
Query: 370 SQAPPPPMT--------SAPPP-----------------------ITPPPGHIIAQMPPY 398
Q PPPPM PPP + PPP ++ PP
Sbjct: 425 MQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPP- 483
Query: 399 MNHPPPGPPPPQHGGP----------PVTAPPPHHYNPNSLPQFTEDQGTLSPPFTQPGG 448
PP G PPP GP P PPP +S P + T + G
Sbjct: 484 ---PPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGS 540
Query: 449 MSPGIW----PAPRGPPPPPRLQGPPSQTPLP 476
+ P W A P P++QG P+ PLP
Sbjct: 541 IPP--WQQQQAAAAASPGAPQMQGNPTMVPLP 570
Score = 50.8 bits (120), Expect = 3e-06
Identities = 59/208 (28%), Positives = 72/208 (34%), Gaps = 50/208 (24%)
Query: 307 EPPPPAPAPAHHHPEYQGQPVVSHPHHIMPPQQHYAPPPPPPPPISHPMPHPPQAAGTP- 365
E P PA + P P+ S P P A PPPP +S PP P
Sbjct: 322 EAPVPASVGSTSGPATT--PLASAPRPAAP-----ANNPPPPSLMSTTQSRPPWMNSGPS 374
Query: 366 -----HLVYSQAPPPPMTSAPPPITPPP------GHIIAQMPPYMNHPPPG----PPPPQ 410
H ++ P P P P P GH M N PPP PPPP
Sbjct: 375 ESRPYHGMHGGGPGGP--GGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPM 432
Query: 411 HGGPPVTAPPPHHYNPNSLPQFTEDQGTLSPPFTQPGGMSP---GIWPAPRG----PPPP 463
+ GP PP H+ P PP Q G +P G++ +G PPPP
Sbjct: 433 NQGPH----PPGHHGP--------------PPMDQYLGSTPVGSGVYRLHQGKGMMPPPP 474
Query: 464 PRLQGPPSQTPLPGPHHPDQTRYRPYYQ 491
+ PP P P P P+ Q
Sbjct: 475 MGMMPPPPPPPSGQPPPPPSGPLPPWQQ 502
>gi|150417989 cyclin K isoform 1 [Homo sapiens]
Length = 580
Score = 85.1 bits (209), Expect = 1e-16
Identities = 85/318 (26%), Positives = 109/318 (34%), Gaps = 73/318 (22%)
Query: 226 KHHMSHIPPKQHIMMPPPPLQHVPH---------EHYNQPHEDIRAPPAELSMAPPPPRS 276
K M H P H + PP LQ P ++P + + P + + P +
Sbjct: 262 KQQMPHHTP--HQLQQPPSLQPTPQVPQVQQSQPSQSSEPSQPQQKDPQQPAQQQQPAQQ 319
Query: 277 VSQETFRISTRKHSNLITVPIQDDSNSGAREPPPPAP---------APAHHHPEY----- 322
+ + + S+ + V + N A PPP P PAH P+
Sbjct: 320 PKKPSPQPSSPRQVKRAVVVSPKEENKAAEPPPPKIPKIETTHPPLPPAHPPPDRKPPLA 379
Query: 323 ----QGQP-----VVSHPHHIMPPQQHYAPPPPPPPPISHPMPHPPQA------------ 361
+ +P P +PP H AP PPP P P PP +
Sbjct: 380 AALGEAEPPGPVDATDLPKVQIPPPAHPAPVHQPPPLPHRPPPPPPSSYMTGMSTTSSYM 439
Query: 362 --AGTPHLVYSQAPPPPMTSAPPPITPPPGHIIAQMPPYMNH-------PPPGPPPPQHG 412
G L P A PP PP H+ PY H PPP PPPP
Sbjct: 440 SGEGYQSLQSMMKTEGPSYGALPPAYGPPAHL-----PYHPHVYPPNPPPPPVPPPPASF 494
Query: 413 GPPVT-------APPPHHYNPNSLPQFTEDQGTLS-PPFTQPG-GMSPGIWPAPRGPPPP 463
PP PPP YNPN P T + PP PG G+ P +P P PP
Sbjct: 495 PPPAIPPPTPGYPPPPPTYNPNFPPPPPRLPPTHAVPPHPPPGLGLPPASYPPPAVPPGG 554
Query: 464 PRLQGPPSQTPLPGPHHP 481
PP P+P P P
Sbjct: 555 Q----PPVPPPIPPPGMP 568
Score = 84.0 bits (206), Expect = 3e-16
Identities = 78/245 (31%), Positives = 97/245 (39%), Gaps = 74/245 (30%)
Query: 195 KPVTRASLENVHPPIAPPPTEIPERFIMPPDKHHMSHIPPKQHIMMPPPPLQHVPHEHYN 254
KP A+L PP T++P+ I PP +H P + PPPL H P
Sbjct: 375 KPPLAAALGEAEPPGPVDATDLPKVQIPPP-----AHPAP----VHQPPPLPHRP----- 420
Query: 255 QPHEDIRAPPAELSMAPPPPRS----VSQETFRISTRKHSNLITVPIQDDSNSGAREPPP 310
PPPP S +S + +S + +L ++ + + GA P
Sbjct: 421 ---------------PPPPPSSYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSYGALPPAY 465
Query: 311 PAPAPAHHHPEYQGQPVVSHPHHIMPPQQHYAPPPPPPPPISHPMPH-PPQAAGTPHLVY 369
PA +HP H+ PP PPP PPPP S P P PP G P
Sbjct: 466 GPPAHLPYHP------------HVYPPNP--PPPPVPPPPASFPPPAIPPPTPGYP---- 507
Query: 370 SQAPPPPMTS---APPPITPPPGHIIAQMPPYMNHPPPG--------PPP--PQHGGPPV 416
PPPP + PPP PP H + PP HPPPG PPP P G PPV
Sbjct: 508 ---PPPPTYNPNFPPPPPRLPPTHAV---PP---HPPPGLGLPPASYPPPAVPPGGQPPV 558
Query: 417 TAPPP 421
P P
Sbjct: 559 PPPIP 563
Score = 77.8 bits (190), Expect = 2e-14
Identities = 75/286 (26%), Positives = 97/286 (33%), Gaps = 81/286 (28%)
Query: 202 LENVHPPIAPPPTEIPERFIMPPDKHHMSHIPPKQHIMMPPPPLQHVPHEHYNQPHEDIR 261
+E HPP+ PP P+R PP + P + P +P + P +
Sbjct: 358 IETTHPPL-PPAHPPPDR--KPPLAAALGEAEPPGPVDATDLPKVQIPPPAHPAP---VH 411
Query: 262 APPAELSMAPPPPRS-----VSQETFRISTRKHSNLITVPIQDDSNSGAREPPPPAPAPA 316
PP PPPP S +S + +S + +L ++ + + GA P PA
Sbjct: 412 QPPPLPHRPPPPPPSSYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSYGALPPAYGPPAHL 471
Query: 317 HHHPEYQGQPVVSHPHHIMPPQQHYAPPPPPPPPISHPMPHPPQAAGTPHLVYSQAPPPP 376
+HP H PP PPPPP+ PPP
Sbjct: 472 PYHP-------------------HVYPPNPPPPPV----------------------PPP 490
Query: 377 MTSAPPPITPPPGHIIAQMPPYMNHPPPGPPPPQHGG-----PPVTAPPPHHYNPNSLPQ 431
S PPP PPP P PPPP PP PP H P+ P
Sbjct: 491 PASFPPPAIPPP-------------TPGYPPPPPTYNPNFPPPPPRLPPTHAVPPHPPPG 537
Query: 432 FTEDQGTLSPPFTQPGGMSPGIWPAPRGPPPPPRLQGPPSQTPLPG 477
+ PP PGG P PPP P PP P+ G
Sbjct: 538 LGLPPASYPPPAVPPGGQPP-------VPPPIP----PPGMPPVGG 572
Score = 72.8 bits (177), Expect = 7e-13
Identities = 77/275 (28%), Positives = 106/275 (38%), Gaps = 50/275 (18%)
Query: 246 QHVPHEHYNQPHEDIRAPPAELSMAPPPPRSVSQETFRISTRKHSNLITVPIQDDSNSGA 305
Q +PH + PH+ ++ PP S+ P P Q+ S S+ + P Q D A
Sbjct: 263 QQMPH---HTPHQ-LQQPP---SLQPTPQVPQVQQ----SQPSQSSEPSQPQQKDPQQPA 311
Query: 306 REPPPPAPAPAHHHPEYQGQPVVSHPHHIMPPQQHYA--PPPP---------PPPPISHP 354
++ P A P P+ V + P +++ A PPPP PP P +HP
Sbjct: 312 QQQQP-AQQPKKPSPQPSSPRQVKRAVVVSPKEENKAAEPPPPKIPKIETTHPPLPPAHP 370
Query: 355 MPH--PPQAAGTPHLVYSQAPPP--------PMTSAPPPITPPPGHIIAQMPPYMNHPPP 404
P PP AA +A PP P PPP P P H Q PP + PPP
Sbjct: 371 PPDRKPPLAAAL-----GEAEPPGPVDATDLPKVQIPPPAHPAPVH---QPPPLPHRPPP 422
Query: 405 GPPPPQHGGPPVTAPPPHHYNPNSLPQFTEDQG----TLSPPFTQPGGMS--PGIWPAPR 458
PP G T+ SL + +G L P + P + P ++P
Sbjct: 423 PPPSSYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSYGALPPAYGPPAHLPYHPHVYPPNP 482
Query: 459 GPPP---PPRLQGPPSQTPLPGPHHPDQTRYRPYY 490
PPP PP PP+ P + P Y P +
Sbjct: 483 PPPPVPPPPASFPPPAIPPPTPGYPPPPPTYNPNF 517
Score = 44.3 bits (103), Expect = 3e-04
Identities = 43/170 (25%), Positives = 55/170 (32%), Gaps = 20/170 (11%)
Query: 323 QGQPVVSH--PHHIMPPQQHYAPPPPPPPPISHPMPHPPQAAGTPHLVYSQAP------- 373
QG+ + H PH + P P P P + P P Q P
Sbjct: 260 QGKQQMPHHTPHQLQQPPS--LQPTPQVPQVQQSQPSQSSEPSQPQQKDPQQPAQQQQPA 317
Query: 374 PPPMTSAPPPITPPPGHIIAQMPPYMNHPPPGPPPPQHGGPPVTAP--PPHHYNPNSLPQ 431
P +P P +P + P + PPPP+ T P PP H P+ P
Sbjct: 318 QQPKKPSPQPSSPRQVKRAVVVSPKEENKAAEPPPPKIPKIETTHPPLPPAHPPPDRKPP 377
Query: 432 FTEDQGTLSPPFTQPGGMSPGIWPAPRGPPPPPRLQGPPSQTPLPGPHHP 481
G P PG + P + PPP P P P PH P
Sbjct: 378 LAAALGEAEP----PGPVDATDLPKVQIPPP---AHPAPVHQPPPLPHRP 420
Score = 42.4 bits (98), Expect = 0.001
Identities = 44/162 (27%), Positives = 50/162 (30%), Gaps = 57/162 (35%)
Query: 194 GKPVTRASLENVHPPIAPPPTEIPERFIMPPDKHHMSHIPPKQHIMMPPPPLQHVPHEHY 253
G P +V+PP PPP P PP IPP PPPP Y
Sbjct: 466 GPPAHLPYHPHVYPPNPPPPPVPPPPASFPPPA-----IPPPTPGYPPPPPT-------Y 513
Query: 254 NQPHEDIRAPPAELSMAPPPPRSVSQETFRISTRKHSNLITVPIQDDSNSGAREPPPPAP 313
N + PPPPR PP A
Sbjct: 514 NP------------NFPPPPPRL-------------------------------PPTHAV 530
Query: 314 APAHHHPEYQGQPVVSHPHHIMPPQQHYAPPPPPPPPISHPM 355
P H P G P S+P +PP PPP PPP P+
Sbjct: 531 PP--HPPPGLGLPPASYPPPAVPPGGQPPVPPPIPPPGMPPV 570
>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
subunit [Homo sapiens]
Length = 551
Score = 84.7 bits (208), Expect = 2e-16
Identities = 64/183 (34%), Positives = 69/183 (37%), Gaps = 53/183 (28%)
Query: 303 SGAREPPPPAPAPAHHHPEYQGQPVVSHPHHIMPPQQHYAPPPPPPPPISHPMPH--PPQ 360
+G PPPP PA GQ PP+ PP PP PP P PP
Sbjct: 221 AGPGGPPPPFPA---------GQT---------PPRPPLGPPGPPGPPGPPPPGQVLPPP 262
Query: 361 AAGTPHLVYSQAPPPPMTSAPPPITPPPGHIIAQMPPYMNHPPPGPPPPQHGGPPVTAPP 420
AG P+ PPPP+ P PP + PPGPPPP G P PP
Sbjct: 263 LAGPPN--RGDRPPPPVLFPGQPFGQPP----------LGPLPPGPPPPVPGYGPPPGPP 310
Query: 421 PHHYNPNSLPQFTEDQGTLSPPFTQPGGMSPGIWPAPRGPP----PPPRLQGPPSQTPLP 476
P P PP P G P P P GPP PPP L GPP P P
Sbjct: 311 PPQQGP--------------PP---PPGPFPPRPPGPLGPPLTLAPPPHLPGPPPGAPPP 353
Query: 477 GPH 479
PH
Sbjct: 354 APH 356
Score = 82.8 bits (203), Expect = 6e-16
Identities = 74/239 (30%), Positives = 89/239 (37%), Gaps = 59/239 (24%)
Query: 241 PPPPLQHVPHEHYNQPHEDIRAPPAELSMAPPPPRSVSQETFRISTRKHSNLITVPIQDD 300
PPPP P + P PPPP V + P+
Sbjct: 226 PPPPFP----AGQTPPRPPLGPPGPPGPPGPPPPGQV---------------LPPPLAGP 266
Query: 301 SNSGAREPPPPAPAPAHHHPEYQGQPVVSHPHHIMPPQQHYAPPPPPPPPISHPMPHPPQ 360
N G R PPP + GQP P +PP PPPP P P P PPQ
Sbjct: 267 PNRGDRPPPPVL---------FPGQPFGQPPLGPLPP----GPPPPVPGYGPPPGPPPPQ 313
Query: 361 AAGTPHLVYSQAPPPPMTSAPP----PITPPPGHIIAQMPPYMNHPPPGPPPPQHGGPPV 416
Q PPPP PP P+ PP + PP++ PPPG PPP P
Sbjct: 314 ----------QGPPPPPGPFPPRPPGPLGPP---LTLAPPPHLPGPPPGAPPPAPHVNPA 360
Query: 417 TAPPPHHYNPNSLPQFTEDQGTLSPPFTQPGGMSPGIWPAPRGPPPPPRLQGPPSQTPL 475
PPP NS ++ +G PP T P G P P RG PP + ++TPL
Sbjct: 361 FFPPP----TNSGMPTSDSRG---PPPTDPYGRPP---PYDRGDYGPPGREMDTARTPL 409
Score = 60.8 bits (146), Expect = 3e-09
Identities = 46/115 (40%), Positives = 50/115 (43%), Gaps = 21/115 (18%)
Query: 373 PPPPMTSAPPPITPPPGHIIAQMPPYMNHPPPGPPPPQHGGPPVTAPPPHHYNPNSLPQF 432
PPPP + P PP G PP PPGPPPP PP A PP+ + P
Sbjct: 226 PPPPFPAGQTPPRPPLG---PPGPP----GPPGPPPPGQVLPPPLAGPPNRGDRPPPPVL 278
Query: 433 TEDQGTLSPPFTQP--GGMSPGIWPAPRG----PPPPPRLQGPPSQTPLPGPHHP 481
Q PF QP G + PG P G P PPP QGPP P PGP P
Sbjct: 279 FPGQ-----PFGQPPLGPLPPGPPPPVPGYGPPPGPPPPQQGPP---PPPGPFPP 325
Score = 55.8 bits (133), Expect = 8e-08
Identities = 42/106 (39%), Positives = 44/106 (41%), Gaps = 19/106 (17%)
Query: 383 PITPPPGHIIAQMPPYMNHPPPGPPPPQHGGPP-VTAPPPHHYNPNSLPQFTEDQGTLSP 441
P PPP Q PP PPGPP P PP PPP PN +G P
Sbjct: 223 PGGPPPPFPAGQTPPRPPLGPPGPPGPPGPPPPGQVLPPPLAGPPN--------RGDRPP 274
Query: 442 PFT----QPGGMSPGIWPAPRGPPPPPRLQGPPSQTPLPGPHHPDQ 483
P QP G P + P P GPPPP GPP PGP P Q
Sbjct: 275 PPVLFPGQPFGQPP-LGPLPPGPPPPVPGYGPP-----PGPPPPQQ 314
Score = 32.3 bits (72), Expect = 1.0
Identities = 23/68 (33%), Positives = 29/68 (42%), Gaps = 15/68 (22%)
Query: 426 PNSLP---QFTEDQGTLSPPFTQPGG-------MSPGIWPAPRGPPP-----PPRLQGPP 470
P ++P +F G PP P G + P P P GPPP PP L GPP
Sbjct: 208 PGAVPGGDRFPGPAGPGGPPPPFPAGQTPPRPPLGPPGPPGPPGPPPPGQVLPPPLAGPP 267
Query: 471 SQTPLPGP 478
++ P P
Sbjct: 268 NRGDRPPP 275
Score = 29.6 bits (65), Expect = 6.5
Identities = 26/69 (37%), Positives = 31/69 (44%), Gaps = 10/69 (14%)
Query: 418 APPPHHYNPNSLPQFTEDQGTLSPPFTQPGGMSPGIWPAPRGP--PPPPRLQG-PPSQTP 474
A PP + + PQ +G P PGG +P P GP PPPP G P + P
Sbjct: 186 AGPPGGSSRAAFPQGGRGRGRF--PGAVPGGDR---FPGPAGPGGPPPPFPAGQTPPRPP 240
Query: 475 L--PGPHHP 481
L PGP P
Sbjct: 241 LGPPGPPGP 249
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 84.3 bits (207), Expect = 2e-16
Identities = 84/309 (27%), Positives = 107/309 (34%), Gaps = 42/309 (13%)
Query: 208 PIAPPPTEIPERFIMPPDKHHMSH--IPPKQHIMMPPPPLQHVPHEHYNQ-PHEDIRAPP 264
P+A PP + P +PP + S PP + P P + H Q P +PP
Sbjct: 388 PLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPP 447
Query: 265 AELSMAPPPPRSVSQETFRISTRKHSNLITVPIQDDSN-------SGAREPPPPAPAPAH 317
+ +PP VS S S L P+Q + S + PPP AP P
Sbjct: 448 VQAPFSPPASPPVSPSATPPSQAPPS-LAAPPLQVPPSPPASPPMSPSATPPPQAPPPLA 506
Query: 318 HHPEYQGQPVVSHPHHIMPPQQHYAPPPP---------------PPPPISHPMPHPPQAA 362
P +P P + P P PP P P++ P P P
Sbjct: 507 APPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVL 566
Query: 363 GTPHLVYSQAPPPPMTSAPPPITPPPGHIIAQMPPYMNHP-PPGPPPPQHGGPPVTAPPP 421
P L +PP T P P PG + P + PGPPPP P T P
Sbjct: 567 AAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGP 626
Query: 422 ----HHYNPNSLPQFTE--DQG------TLSPPFTQPGGMSPGIWPAPRGPPPPPRLQGP 469
H + S P+ D G PP + P W RGP PP +G
Sbjct: 627 DLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAW--SRGPAPPLAFRGA 684
Query: 470 PSQTPLPGP 478
P PLP P
Sbjct: 685 PG-APLPWP 692
Score = 82.8 bits (203), Expect = 6e-16
Identities = 80/296 (27%), Positives = 104/296 (35%), Gaps = 68/296 (22%)
Query: 202 LENVHPPIAPPPTEIPERFIMPPDKHHMSHIPPKQHIM-MPPPPLQHVPHEH-------- 252
L+ + PP PP + + P ++ P + PP L PH
Sbjct: 277 LQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLAT 336
Query: 253 -YNQPHEDIRAPPAELSMAPPPPRSVSQETFRIST----RKHSNLITVPIQDDSNSGARE 307
APP+ ++ PP SQ T + + HS L + P+ S
Sbjct: 337 PLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPL-----SPLAT 391
Query: 308 PPPPAPAPAHHHPEYQGQPVVSHPHHIMPPQQHYAPPPPPPP--PISHPMPHPPQAAGTP 365
PPP AP P +PP Q PP PP P++ P P P A
Sbjct: 392 PPPQAP-----------------PALALPPLQAPPSPPASPPLSPLATPSPQAPNALAV- 433
Query: 366 HLVYSQAPPPPMTSAPPPITPPPGHIIAQMPPYMNHPPPGPPPPQHGGPPVTAPPPHHYN 425
HL+ + PPP P +PP A P + PP PP PP+ PP
Sbjct: 434 HLLQAPFSPPPSPPVQAPFSPP-----ASPPVSPSATPPSQAPPSLAAPPLQVPP----- 483
Query: 426 PNSLPQFTEDQGTLSPPFTQPGGMSPGIWPAPRGPPPPPRLQGPPSQTPLPGPHHP 481
SPP + P MSP P P+ PPP L PP Q P P P
Sbjct: 484 --------------SPPASPP--MSPSATPPPQAPPP---LAAPPLQLAKPPPQAP 520
Score = 73.6 bits (179), Expect = 4e-13
Identities = 81/303 (26%), Positives = 111/303 (36%), Gaps = 52/303 (17%)
Query: 195 KPVTRASLENVHPPIAPPPTEIPERFIMPPDKHHMSHIPPKQHIMMPPPPLQHVPHEHYN 254
+P +R SL + P++ P P P H S PK + PP +
Sbjct: 236 RPASR-SLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQV--------T 286
Query: 255 QPHEDIRAPPAELSMAP---PPPRSV--SQETFRISTRKHSNLIT------VPIQDDSNS 303
P +D LS +P P P + SQ + HS+ +T +P+ S S
Sbjct: 287 PPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPS 346
Query: 304 GARE----PPPPAPAPAHHHPEYQGQPVVSHPHHIMPPQQHYAPPPPPPPPISHPMPHPP 359
P PPA P+ G P + H +P PP P++ P P P
Sbjct: 347 APPSLQTLPSPPATPPSQATTSL-GSPTLQATHSFLPS--------PPLSPLATPPPQAP 397
Query: 360 QAAGTPHLVYSQAPPPPMTSAP-PPITPPPGHIIAQMPPYMNHPPPGPPPPQHGGPPVTA 418
A P L QAPP P S P P+ P + ++ P PPP PPV A
Sbjct: 398 PALALPPL---QAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPP----SPPVQA 450
Query: 419 PPPHHYNPNSLPQFTEDQGTLSPPFTQPGGMSPGIWPAPRGPPPPPRLQGPPSQTPLPGP 478
P ++P + P +SP T P P + P PP P P S + P P
Sbjct: 451 P----FSPPASPP-------VSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPP 499
Query: 479 HHP 481
P
Sbjct: 500 QAP 502
Score = 61.2 bits (147), Expect = 2e-09
Identities = 74/268 (27%), Positives = 97/268 (36%), Gaps = 48/268 (17%)
Query: 207 PPIAPPPTEIPERFIMPPDKHHMSHIPPKQHIMMPPPPLQHVPHEHYNQPHEDIRAPPAE 266
PP APPP P + P PP+ + PPLQ +P + P + +P A
Sbjct: 498 PPQAPPPLAAPPLQLAKP--------PPQAPPALATPPLQALPSPPASFPGQAPFSPSAS 549
Query: 267 LSMAP---PPPRSVSQETFRISTRKHSNLITVPIQDDSNSGAREPP-PPAPAPAHHHPEY 322
L M+P PPP++ + L+ VP ++ + P PP P P
Sbjct: 550 LPMSPLATPPPQAPPVLA--------APLLQVPPSPPASPTLQAPRRPPTPGP------- 594
Query: 323 QGQPVVSHPHHIMPPQQHYAPPPPPPPP------ISHP--MPHPPQAAGTPHLVYSQAPP 374
VS P + AP PPPPP +S P H A TP +
Sbjct: 595 --DTSVSGPRLTLA----LAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSG 648
Query: 375 PPMTSAPPPITPPPGHIIAQMPPYMNHPPPGPPPPQHGGPPVTAPPPHHYNPNS---LPQ 431
P +A +PPP +A P P PP G P P P P S L
Sbjct: 649 PEGGAAA---SPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCT 705
Query: 432 FTEDQGTLSPPFTQPGGMSPGIWPAPRG 459
E +G S PG + PG P G
Sbjct: 706 IYETEGPESAT-PAPGALDPGPSPGTSG 732
Score = 56.6 bits (135), Expect = 5e-08
Identities = 75/299 (25%), Positives = 98/299 (32%), Gaps = 68/299 (22%)
Query: 198 TRASLENVHPPIAP-PPTEIPERFIMPPDKHHMSHIPPKQHIMMPPPPLQHVPHEHYNQP 256
T L P P PPTE P + + +H + P
Sbjct: 185 TEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAAR------------------- 225
Query: 257 HEDIRAPPAELSMAPPPPRSVSQETFRISTRKHSNLITVPIQDDSNSGAREPPPPAPAPA 316
R P A + P RS+S P+ + SG P APA
Sbjct: 226 ----RRPSAGGGLQRPASRSLSSSA-------------TPLSSPARSGPSARGTPR-APA 267
Query: 317 H-HHPEYQGQPVVSHPHHIMPPQQHYAPP--PPPPPPISHPMPH-------PPQAAGTPH 366
H P+ +G + P + PP++ AP P P++ P P PP TPH
Sbjct: 268 HPSQPKPKGLQAL-RPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPH 326
Query: 367 ---LVYSQAPPPPMTSAPPPITPPPGHIIAQMPPYMNHPPPGPPPPQHGGPPVTAPPPHH 423
L A P P+ APP + PP PP PP G P + A H
Sbjct: 327 SSSLTCQLATPLPL--APPSPSAPPSLQTLPSPPAT---PPSQATTSLGSPTLQAT--HS 379
Query: 424 YNPNSLPQFTEDQGTLSPPFTQPGGMSPGIWPAPRGPPPPPRLQGPPSQTPLPGPHHPD 482
+ P+ LSP T P P + P PP P P S P P P+
Sbjct: 380 FLPSP---------PLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPN 429
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 84.3 bits (207), Expect = 2e-16
Identities = 84/309 (27%), Positives = 107/309 (34%), Gaps = 42/309 (13%)
Query: 208 PIAPPPTEIPERFIMPPDKHHMSH--IPPKQHIMMPPPPLQHVPHEHYNQ-PHEDIRAPP 264
P+A PP + P +PP + S PP + P P + H Q P +PP
Sbjct: 349 PLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPP 408
Query: 265 AELSMAPPPPRSVSQETFRISTRKHSNLITVPIQDDSN-------SGAREPPPPAPAPAH 317
+ +PP VS S S L P+Q + S + PPP AP P
Sbjct: 409 VQAPFSPPASPPVSPSATPPSQAPPS-LAAPPLQVPPSPPASPPMSPSATPPPQAPPPLA 467
Query: 318 HHPEYQGQPVVSHPHHIMPPQQHYAPPPP---------------PPPPISHPMPHPPQAA 362
P +P P + P P PP P P++ P P P
Sbjct: 468 APPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVL 527
Query: 363 GTPHLVYSQAPPPPMTSAPPPITPPPGHIIAQMPPYMNHP-PPGPPPPQHGGPPVTAPPP 421
P L +PP T P P PG + P + PGPPPP P T P
Sbjct: 528 AAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGP 587
Query: 422 ----HHYNPNSLPQFTE--DQG------TLSPPFTQPGGMSPGIWPAPRGPPPPPRLQGP 469
H + S P+ D G PP + P W RGP PP +G
Sbjct: 588 DLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAW--SRGPAPPLAFRGA 645
Query: 470 PSQTPLPGP 478
P PLP P
Sbjct: 646 PG-APLPWP 653
Score = 79.3 bits (194), Expect = 7e-15
Identities = 80/254 (31%), Positives = 97/254 (38%), Gaps = 43/254 (16%)
Query: 262 APPAELSMAPPPPRSVSQETFRIST----RKHSNLITVPIQDDSNSGAREPPPPAPAPAH 317
APP+ ++ PP SQ T + + HS L + P+ + + PP A P
Sbjct: 308 APPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQ 367
Query: 318 HHPEYQGQPVVSHPHHIMPP----------QQHYAPPPPPP--PPISHPMPHPPQAAGTP 365
P P +S P Q ++PPP PP P S P P + TP
Sbjct: 368 APPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATP 427
Query: 366 HLVYSQAPP----PPMTSAPPPITPPPGHIIAQMPPYMNHPPPGPPPPQHGGPPVTAPPP 421
SQAPP PP+ P P PP A PP PP PP Q PP APP
Sbjct: 428 P---SQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAP-PPLAAPPLQLAKPPPQAPPA 483
Query: 422 HHYNP----NSLPQFTEDQGTLSPPFTQPGGMSPGIWPAPRGPP--PPPRLQGPPS---- 471
P S P Q SP + P MSP P P+ PP P LQ PPS
Sbjct: 484 LATPPLQALPSPPASFPGQAPFSPSASLP--MSPLATPPPQAPPVLAAPLLQVPPSPPAS 541
Query: 472 -------QTPLPGP 478
+ P PGP
Sbjct: 542 PTLQAPRRPPTPGP 555
Score = 66.6 bits (161), Expect = 5e-11
Identities = 76/288 (26%), Positives = 102/288 (35%), Gaps = 52/288 (18%)
Query: 195 KPVTRASLENVHPPIAPPPTEIPERFIMPPDKHHMSHIPPKQHIMMPPPPLQHVPHEHYN 254
+P +R SL + P++ P P P H S PK + PP +
Sbjct: 227 RPASR-SLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQV--------T 277
Query: 255 QPHEDIRAPPAELSMAPPPPRSVSQETFRISTRKHSNLITVPIQDDSNSGAREPPPPAPA 314
P +D LS +P S S S +L T+P PPA
Sbjct: 278 PPRKDAAPALGPLSSSPLATPSPSAPP---SPSAPPSLQTLP------------SPPATP 322
Query: 315 PAHHHPEYQGQPVVSHPHHIMPPQQHYAPPPPPPPPISHPMPHPPQAAGTPHLVYSQAPP 374
P+ G P + H +P PP P++ P P P A P L QAPP
Sbjct: 323 PSQATTSL-GSPTLQATHSFLPS--------PPLSPLATPPPQAPPALALPPL---QAPP 370
Query: 375 PPMTSAP-PPITPPPGHIIAQMPPYMNHPPPGPPPPQHGGPPVTAPPPHHYNPNSLPQFT 433
P S P P+ P + ++ P PPP PPV AP ++P + P
Sbjct: 371 SPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPP----SPPVQAP----FSPPASPP-- 420
Query: 434 EDQGTLSPPFTQPGGMSPGIWPAPRGPPPPPRLQGPPSQTPLPGPHHP 481
+SP T P P + P PP P P S + P P P
Sbjct: 421 -----VSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAP 463
Score = 63.5 bits (153), Expect = 4e-10
Identities = 78/303 (25%), Positives = 101/303 (33%), Gaps = 68/303 (22%)
Query: 198 TRASLENVHPPIAP-PPTEIPERFIMPPDKHHMSHIPPKQHIMMPPPPLQHVPHEHYNQP 256
T L P P PPTE P + + +H + P
Sbjct: 176 TEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAAR------------------- 216
Query: 257 HEDIRAPPAELSMAPPPPRSVSQETFRISTRKHSNLITVPIQDDSNSGAREPPPPAPAPA 316
R P A + P RS+S P+ + SG P APA
Sbjct: 217 ----RRPSAGGGLQRPASRSLSSSA-------------TPLSSPARSGPSARGTPR-APA 258
Query: 317 HHHPEYQGQPVVSHPHHIMPPQQHYAPPPPPPPPISHPMPHPPQAAGTPHLVYSQAPPPP 376
H QP + PPQ PP P P+ P A +P S + PP
Sbjct: 259 H-----PSQPKPKGLQALRPPQ--VTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPS 311
Query: 377 MTSAP-PPITPPPGHIIAQMPP-------YMNHPPPGP---PPPQHGG----PPVTAPPP 421
+ + P PP TPP + P ++ PP P PPPQ PP+ APP
Sbjct: 312 LQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPS 371
Query: 422 HHYNPNSLPQFTEDQGTLSPPFTQPGGMSPGIWPAPRGPPPPPRLQGPPSQTPLPGPHHP 481
+P P T P P ++ + AP PPP P +Q P S P P P
Sbjct: 372 PPASPPLSPLAT-------PSPQAPNALAVHLLQAPFSPPPSPPVQAPFS-PPASPPVSP 423
Query: 482 DQT 484
T
Sbjct: 424 SAT 426
Score = 61.2 bits (147), Expect = 2e-09
Identities = 74/268 (27%), Positives = 97/268 (36%), Gaps = 48/268 (17%)
Query: 207 PPIAPPPTEIPERFIMPPDKHHMSHIPPKQHIMMPPPPLQHVPHEHYNQPHEDIRAPPAE 266
PP APPP P + P PP+ + PPLQ +P + P + +P A
Sbjct: 459 PPQAPPPLAAPPLQLAKP--------PPQAPPALATPPLQALPSPPASFPGQAPFSPSAS 510
Query: 267 LSMAP---PPPRSVSQETFRISTRKHSNLITVPIQDDSNSGAREPP-PPAPAPAHHHPEY 322
L M+P PPP++ + L+ VP ++ + P PP P P
Sbjct: 511 LPMSPLATPPPQAPPVLA--------APLLQVPPSPPASPTLQAPRRPPTPGP------- 555
Query: 323 QGQPVVSHPHHIMPPQQHYAPPPPPPPP------ISHP--MPHPPQAAGTPHLVYSQAPP 374
VS P + AP PPPPP +S P H A TP +
Sbjct: 556 --DTSVSGPRLTLA----LAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSG 609
Query: 375 PPMTSAPPPITPPPGHIIAQMPPYMNHPPPGPPPPQHGGPPVTAPPPHHYNPNS---LPQ 431
P +A +PPP +A P P PP G P P P P S L
Sbjct: 610 PEGGAAA---SPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCT 666
Query: 432 FTEDQGTLSPPFTQPGGMSPGIWPAPRG 459
E +G S PG + PG P G
Sbjct: 667 IYETEGPESAT-PAPGALDPGPSPGTSG 693
>gi|151301053 RNA binding motif protein 33 [Homo sapiens]
Length = 1170
Score = 84.3 bits (207), Expect = 2e-16
Identities = 106/378 (28%), Positives = 137/378 (36%), Gaps = 82/378 (21%)
Query: 160 RGSLFMCSIVQGCKRTYLSQRDLQAHINHRHMRAGKPVTRASLENVHPPIAPPPTEIPER 219
RG MC V G +R ++R H A P + PP PPP + P R
Sbjct: 279 RGGPLMCRGV-GDQRRESTERGRMKD----HRPALLPTQPPVVPQAPPPPPPPPQQQPIR 333
Query: 220 FIMPPDK----------HHMS-----HIPPK---QHIMMPPPPL--QHVPHEHYNQPHED 259
+ P HH S H+PP+ +MM PPP+ Q + H N +
Sbjct: 334 SLFQPQPLQPLLPVQHPHHPSPPQGMHMPPQLETPRMMMTPPPVTPQQPKNIHINPHFKG 393
Query: 260 IRAPPAELSMAPPP--------------PRSVSQETFRISTRKHSNLITVPIQDDSNSGA 305
P ++ + P P P Q T S +P+QD
Sbjct: 394 TVVTPVQVPLLPVPSQPRPAVGPQRFPGPPEFPQHTPGPVPNSFSQPPRLPLQDQW---- 449
Query: 306 REPPPPAPAPAHHHPEYQGQPVVSHPHHIMPPQQHYAPPPPPPPPI----SHPMP-HPPQ 360
R PPPP G+P P H+ Q+ +PPPPPPPP SHP+P P
Sbjct: 450 RAPPPPQDRDPFFLG-VSGEP--RFPSHLFLEQR--SPPPPPPPPTLLNSSHPVPTQSPL 504
Query: 361 AAGTPHLVYSQAPPPPMTSAPPPITP---PPGHI---------IAQMPPYMNHPPPGPPP 408
P ++Q P+ P+ P PPG + A P++ PP P
Sbjct: 505 PFTQPGPAFNQQGQQPVFPRERPVRPALQPPGPVGILHFSQPGSATTRPFI--PPRQPFL 562
Query: 409 PQHGGPPVTAPPPHHYNPNSLPQFTEDQGTLSPPFT---QPGGMSPGIWPAPRGPPPPPR 465
P G P + P H PN QG L PP QP P P P+ PP
Sbjct: 563 PGPGQPFL----PTHTQPNL-------QGPLHPPLPPPHQPQPQQPQQQPPPQHQPPHQP 611
Query: 466 LQGPPSQTPLPGPHHPDQ 483
PP Q P P HP Q
Sbjct: 612 PHQPPPQHQ-PPPQHPPQ 628
Score = 61.2 bits (147), Expect = 2e-09
Identities = 59/215 (27%), Positives = 74/215 (34%), Gaps = 45/215 (20%)
Query: 202 LENVHPPIAPPP-----------TEIPERFIMP-PDKHHMSHIP------PKQHIMMPPP 243
LE PP PPP T+ P F P P + P P + + PP
Sbjct: 477 LEQRSPPPPPPPPTLLNSSHPVPTQSPLPFTQPGPAFNQQGQQPVFPRERPVRPALQPPG 536
Query: 244 PLQHVPHEHYNQPHEDIRAP--PAELSMAPPPPRSVSQETFRISTRKHSNLITVPIQDDS 301
P+ + H++QP P P P P + + T NL
Sbjct: 537 PVGIL---HFSQPGSATTRPFIPPRQPFLPGPGQPF------LPTHTQPNL--------- 578
Query: 302 NSGAREPPPPAPAPAHHHPEYQGQPVVSHPHHIMPPQQHYAPPPPPPPPISHPMPHPPQA 361
G PP P P H P+ Q P H P Q + PPP PP HP HPPQ
Sbjct: 579 -QGPLHPPLPPP----HQPQPQQPQQQPPPQHQPPHQPPHQPPPQHQPPPQHPPQHPPQH 633
Query: 362 AGTPHLVYSQAPPPPMTSAPPPITPPPGHIIAQMP 396
H + PPPP+ P P H+ P
Sbjct: 634 QHHHHHHHLSVPPPPLMPMSQPQFRP--HVQTAQP 666
Score = 56.6 bits (135), Expect = 5e-08
Identities = 89/318 (27%), Positives = 110/318 (34%), Gaps = 86/318 (27%)
Query: 179 QRDLQAHINHRHMRAGKPVTRASLENVHPPIAPPPTEIPERFIMPPD--KHHMSHIP--- 233
Q+ HIN H + G VT + + P P P P+RF PP+ +H +P
Sbjct: 380 QQPKNIHINP-HFK-GTVVTPVQVPLLPVPSQPRPAVGPQRFPGPPEFPQHTPGPVPNSF 437
Query: 234 ------PKQHIMMPPPPLQH-------VPHEHYNQPHEDI--RAPPAELSMAPPPPRSVS 278
P Q PPP Q V E H + R+PP PPPP ++
Sbjct: 438 SQPPRLPLQDQWRAPPPPQDRDPFFLGVSGEPRFPSHLFLEQRSPPP-----PPPPPTLL 492
Query: 279 QETFRISTRKHSNLITVPIQDDSNSGA-----REPP------PPAPAPAHHHPEYQGQPV 327
+ + T+ T P + G RE P PP P H QP
Sbjct: 493 NSSHPVPTQSPLPF-TQPGPAFNQQGQQPVFPRERPVRPALQPPGPVGILHF----SQPG 547
Query: 328 VSHPHHIMPPQQHYAPPPPPPPPISHPMP------HPPQAAGTPHLVYSQAP---PPPMT 378
+ +PP+Q + P P P +H P HPP PH Q P PPP
Sbjct: 548 SATTRPFIPPRQPFLPGPGQPFLPTHTQPNLQGPLHPPLPP--PHQPQPQQPQQQPPPQH 605
Query: 379 SAP--PPITPPPGHIIAQMPPYM--NHPPP-----------GPPPPQHGGPPVTAPPPHH 423
P PP PPP H Q PP HPP PPPP
Sbjct: 606 QPPHQPPHQPPPQH---QPPPQHPPQHPPQHQHHHHHHHLSVPPPP-------------- 648
Query: 424 YNPNSLPQFTEDQGTLSP 441
P S PQF T P
Sbjct: 649 LMPMSQPQFRPHVQTAQP 666
>gi|160707881 formin 2 [Homo sapiens]
Length = 1722
Score = 84.0 bits (206), Expect = 3e-16
Identities = 87/276 (31%), Positives = 105/276 (38%), Gaps = 57/276 (20%)
Query: 217 PERFIMPPDKHHMSHIPPKQHIMMPPPPLQHVPHEHYNQPHEDIRAPPAELSMAPPPPRS 276
P R + D H P Q I PPPP + QP PP S
Sbjct: 791 PRRISVQLDSHQ-----PTQSISQPPPPPSLLWSAGQGQPGSQ-------------PPHS 832
Query: 277 VSQETFRISTRKHSNLITVPIQDDSNSGAREPPPPAPAPAHHHPEYQGQPVVSHPHHIMP 336
+S E F+ S H + ++ ++ N + PPP P + MP
Sbjct: 833 ISTE-FQTS---HEHSVSSAFKNSCNIPS---PPPLPC--------------TESSSSMP 871
Query: 337 PQQHYAPPPPPPPPISHP------MPHPPQAAGTPHLVYSQAPPPPMTSAP-PPITPPPG 389
PPPPP P ++ P +P PP GT L PPPP+ A PP P PG
Sbjct: 872 GLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEML---PPPPPPLPGAGIPPPPPLPG 928
Query: 390 HIIAQMPPYMNHPPPG-PPPPQHGGPPVTAPPPHHYNPNSLPQFTEDQGTLSPPFTQPGG 448
I +PP P G PPPP G + PPP LP G + PP PG
Sbjct: 929 AGILPLPPL---PGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAG-IPPPPPLPGA 984
Query: 449 MSPGIWPAP-RGPPPPPRLQGP--PSQTPLPGPHHP 481
P P P G PPPP L G P PLPG P
Sbjct: 985 GIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIP 1020
Score = 83.6 bits (205), Expect = 4e-16
Identities = 93/282 (32%), Positives = 101/282 (35%), Gaps = 72/282 (25%)
Query: 211 PPPTEIPERFIMPPDKHHMSHIPPKQHI----MMPPPPLQHVPHEHYNQPHEDIRAPPAE 266
PPP +P I PP + IPP + + PPPPL P I PP
Sbjct: 987 PPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL----------PGAGIPPPPPL 1036
Query: 267 LSMAPPPPRSVSQETFRISTRKHSNLITVPIQDDSNSGAREPPPPAPAPAHHHPEYQGQP 326
PPP + GA PPPP P P P P
Sbjct: 1037 PGAGIPPPPPLP-------------------------GAGIPPPP-PLPGAGIPPPPPLP 1070
Query: 327 VVSHPHHIMPPQQHYA--PPPPPPPPISHPMPHPPQAAGTPHLVYSQAPPPPMTSAPPPI 384
P PP A PPPPP P P P P G P PPPP+ A P
Sbjct: 1071 GAGIPP---PPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIP-------PPPPLPGAGIPP 1120
Query: 385 TPP-PGHIIAQMPPYMNHPPPGPPP-PQHGGPPVTAPPPHHYNPNSLPQFTEDQGTLSPP 442
PP PG I PP P PPP P+ G PP PPP LP + PP
Sbjct: 1121 PPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPP---PPP-------LPG-----AGIPPP 1165
Query: 443 FTQPGGMSPGIWPAPR-GPPPPPRLQGP--PSQTPLPGPHHP 481
PG P P P G PPPP L G P PLPG P
Sbjct: 1166 PPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIP 1207
Score = 83.2 bits (204), Expect = 5e-16
Identities = 92/293 (31%), Positives = 104/293 (35%), Gaps = 72/293 (24%)
Query: 211 PPPTEIPERFIMPPDKHHMSHIPPKQHI----MMPPPPLQHVPHEHYNQPHEDIRAPPAE 266
PPP +P I PP + IPP + + PPPPL P I PP
Sbjct: 998 PPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL----------PGAGIPPPPPL 1047
Query: 267 LSMAPPPPRSVSQETFRISTRKHSNLITVPIQDDSNSGAREPPPPAPAPAHHHPEYQGQP 326
PPP + GA PPPP P P P P
Sbjct: 1048 PGAGIPPPPPLP-------------------------GAGIPPPP-PLPGAGIPPPPPLP 1081
Query: 327 VVSHPHHIMPPQQHYA--PPPPPPPPISHPMPHPPQAAGTPHLVYSQAPPPPMTSAPPPI 384
P PP A PPPPP P + P P P AG P PPPP+ A P
Sbjct: 1082 GAGIPP---PPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIP-------PPPPLPGAGIPP 1131
Query: 385 TPP-PGHIIAQMPPY--MNHPPPGP-------PPPQHGGPPVTAPPPHHYNPNSLPQFTE 434
PP PG I PP + PPP P PPP G + PPP P
Sbjct: 1132 PPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLP 1191
Query: 435 DQGTLSPPFTQPGGMSP-------GIWPAPRGPPPPPR--LQGPPSQTPLPGP 478
G PP G+ P GI PAP P PPP + PP P+ GP
Sbjct: 1192 GVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPGTGIP-PPPLLPVSGP 1243
Score = 75.5 bits (184), Expect = 1e-13
Identities = 80/265 (30%), Positives = 92/265 (34%), Gaps = 52/265 (19%)
Query: 211 PPPTEIPERFIMPPDKHHMSHIPPKQHI----MMPPPPLQHVPHEHYNQPHEDIRAPPAE 266
PPP +P I PP + IPP + + PPPPL P I PP
Sbjct: 1042 PPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL----------PGAGIPPPPPL 1091
Query: 267 LSMAPPPPRSVSQETFRISTRKHSNLITVPIQDDSNSGAREPPPPAP-APAHHHPEYQGQ 325
PPP + + +P PPPP P A P G
Sbjct: 1092 PGAGIPPPPPLPG-------------VGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGA 1138
Query: 326 PVVSHPHHIMPPQQHYAPPPPPPPPISHPMPHPPQAAGTPHLVYSQAPPPPMTSAPPPIT 385
+ P P + PPPPP P P P P AG P PPPP+ P
Sbjct: 1139 GIPPPP----PLPRVGIPPPPPLPGAGIPPPPPLPGAGIP-------PPPPLPGVGIPPP 1187
Query: 386 PP-PGHIIAQMPPYMNHPPPGPPP-PQHGGPPVTAP---------PPHHYNPNSLPQFTE 434
PP PG I PP P PPP P G PP AP PP P S P
Sbjct: 1188 PPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPGTGIPPPPLLPVSGPPLLP 1247
Query: 435 DQGTLSPPFTQPGGMSPGIWPAPRG 459
G+ + P Q G P P P G
Sbjct: 1248 QVGSSTLPTPQVCGFLPP--PLPSG 1270
Score = 73.6 bits (179), Expect = 4e-13
Identities = 84/278 (30%), Positives = 96/278 (34%), Gaps = 61/278 (21%)
Query: 209 IAPPPTEIPERFIMPPDKHHMSHIPPKQHI-MMPPPPLQHVPHEHYNQPHEDIRAPPAEL 267
+ PPP +P + + PP Q M+PPPP PP
Sbjct: 876 VPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPP------------------PPLPG 917
Query: 268 SMAPPPPRSVSQETFRISTRKHSNLITVPIQDDSNSGAREPPPPAPAPAHHHPEYQGQPV 327
+ PPPP + ++ +P GA PPPP P P P P
Sbjct: 918 AGIPPPPPLPG-----------AGILPLP----PLPGAGIPPPP-PLPGAAIPPPPPLPG 961
Query: 328 VSHPHHIMPPQQHYAPPPPPPPPISHPMPHPPQAAGTPHLVYSQAPPPPMTSAP-PPITP 386
P PPP P I P P P AG P PPPP+ A PP P
Sbjct: 962 AGIP----------LPPPLPGAGI--PPPPPLPGAGIP-------PPPPLPGAGIPPPPP 1002
Query: 387 PPGHIIAQMPPYMNHPPPGPPPPQHGGPPVTAPPPHHYNPNSLPQFTEDQGTLSPPFTQP 446
PG I PP P PPP G P PPP P + PP P
Sbjct: 1003 LPGAGIPPPPPLPGAGIPPPPPLPGAGIP---PPPPLPGAGIPPPPPLPGAGIPPPPPLP 1059
Query: 447 GGMSPGIWPAP-RGPPPPPRLQGP--PSQTPLPGPHHP 481
G P P P G PPPP L G P PLPG P
Sbjct: 1060 GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIP 1097
Score = 63.5 bits (153), Expect = 4e-10
Identities = 71/257 (27%), Positives = 84/257 (32%), Gaps = 68/257 (26%)
Query: 211 PPPTEIPERFIMPPDKHHMSHIPPKQHI----MMPPPPLQHVPHEHYNQPHEDIRAPPA- 265
PPP +P I PP + IPP + + PPPPL P I PP
Sbjct: 1097 PPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL----------PGAGIPPPPPL 1146
Query: 266 -ELSMAPPPPRSVSQETFRISTRKHSNLITVPIQDDSNSGAREPPPPAPAPAHHHPEYQG 324
+ + PPPP GA PPPP P P P
Sbjct: 1147 PRVGIPPPPPLP---------------------------GAGIPPPP-PLPGAGIPPPPP 1178
Query: 325 QPVVSHPHHIMPPQQHYAPPPPPP-PPISHPMPHPPQAAGTPHLVYSQAPPPPMTSAPPP 383
P V P PP PPPPP P P P P G P PPP PPP
Sbjct: 1179 LPGVGIPPP--PPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPGTGIPPPP 1236
Query: 384 ITPPPGHIIAQMPPYMNHPPPGPPPPQHGGPPVTAPPPHHYNPNSLPQ------FTEDQG 437
+ P G PP + PQ G + P + P LP +D+G
Sbjct: 1237 LLPVSG------PPLL---------PQVGSSTLPTPQVCGFLPPPLPSGLFGLGMNQDKG 1281
Query: 438 TLSPPFTQPGGMSPGIW 454
+ P M P W
Sbjct: 1282 SRKQPIEPCRPMKPLYW 1298
Score = 33.1 bits (74), Expect = 0.59
Identities = 45/188 (23%), Positives = 60/188 (31%), Gaps = 50/188 (26%)
Query: 344 PPPPPPPISHPMPHPPQAAGTPHLVYSQAPPPPMTSAP-PPITPPPGHIIAQMPPYMNHP 402
P PP +S P P G + P AP P T ++ +P +
Sbjct: 232 PAAPPTAVS---PQPGAFLGLDRFLLG--PSGGAGEAPGSPDTEQALSALSDLPESLAAE 286
Query: 403 PPGPP-PPQHGGPPVTAPPPHHYNPNSLPQFTEDQGTLSPPFTQPG-------------- 447
P P PP GG PV+ P P + P + + + PF + G
Sbjct: 287 PREPQQPPSPGGLPVSEAPSL---PAAQPAAKDSPSSTAFPFPEAGPGEEAAGAPVRGAG 343
Query: 448 -----GMSPGIWPAPRGPP-------------------PPPRLQGP--PSQTPLPGPHHP 481
G APRG P P QGP P+ LPG P
Sbjct: 344 DTDEEGEEDAFEDAPRGSPGEEWAPEVGEDAPQRLGEEPEEEAQGPDAPAAASLPGSPAP 403
Query: 482 DQTRYRPY 489
Q ++PY
Sbjct: 404 SQRCFKPY 411
>gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [Homo
sapiens]
Length = 1636
Score = 82.8 bits (203), Expect = 6e-16
Identities = 83/281 (29%), Positives = 105/281 (37%), Gaps = 44/281 (15%)
Query: 207 PPIAPPPTEIPERFIMPPDKHHMSHIPPKQHIMMPPPPLQHVPHEHYNQPHEDIRAPPAE 266
PP+A P+ P +F P + + P P P + APP
Sbjct: 855 PPVAGLPSAPPPQFSGPELAMAVRPATTTVDSIQAPIPSHTAPRPNPTP------APPPP 908
Query: 267 LSMAPPPPRSVSQETFRISTRKHSNLITVPIQDDSNSGAREPPPPAPAPAHHHPEYQGQP 326
PPP + T+ ++ +P Q +SG PA PA P QP
Sbjct: 909 CFPVPPPQPLPTPYTYPAGAKQ-----PIPAQHHFSSGI-----PAGFPA---PRIGPQP 955
Query: 327 VVSHPHHIMPPQQHYAPPPPPPP-PISHPMPHPPQAAGT--PHLVYSQAPPPPMTSAPPP 383
PH P Q + P PP P P+ HP PPQA G P Y AP P + PPP
Sbjct: 956 ---QPHPQPHPSQAFGPQPPQQPLPLQHPHLFPPQAPGLLPPQSPYPYAPQPGVLGQPPP 1012
Query: 384 ITPP---PGHIIAQMPPY---MNHPPPGPPPPQHGGPPVT---APPPHHYNPNSLP---- 430
PG +P + + P PGPP P H PP+ AP P + P
Sbjct: 1013 PLHTQLYPGPAQDPLPAHSGALPFPSPGPPQPPH--PPLAYGPAPSTRPMGPQAAPLTIR 1070
Query: 431 -QFTEDQGTLSPPFTQPGGMSPGIWPAPRGPP---PPPRLQ 467
+ Q T SP SPG P P PP PPP L+
Sbjct: 1071 GPSSAGQSTPSPHLVPSPAPSPGPGPVPPRPPAAEPPPCLR 1111
Score = 81.3 bits (199), Expect = 2e-15
Identities = 85/319 (26%), Positives = 109/319 (34%), Gaps = 54/319 (16%)
Query: 208 PIAPPPTEIPERFIMP--PDKHHMSHIPPKQHIMMPP--PPLQHVP-----HEHYNQPHE 258
P+ P P + I P P H M P P P L VP H + P+
Sbjct: 790 PLPPGTYSGPTQLIQPRAPGPHAMPVAPGPALYPAPAYTPELGLVPRSSPQHGVVSSPYV 849
Query: 259 DIRAPPAELSMAPPPPRSVSQETFRISTRKHSNLI-TVPIQDDSNSGAREPPPPAPAPA- 316
+ P + PP S ++ R + + ++ S++ R P PAP P
Sbjct: 850 GVGPAPPVAGLPSAPPPQFSGPELAMAVRPATTTVDSIQAPIPSHTAPRPNPTPAPPPPC 909
Query: 317 ------------HHHPEYQGQPVVSHPHHIMPPQQHYAPPPPPPPPISHPMPHPPQAAGT 364
+ +P QP+ + H + P P P HP PHP QA G
Sbjct: 910 FPVPPPQPLPTPYTYPAGAKQPIPAQHHFSSGIPAGFPAPRIGPQPQPHPQPHPSQAFGP 969
Query: 365 -----------PHLVYSQAPPPPMTSAPPPITPPPGHIIAQMPPYMNHPPPGP---PPPQ 410
PHL QAP +P P P PG + PP PGP P P
Sbjct: 970 QPPQQPLPLQHPHLFPPQAPGLLPPQSPYPYAPQPGVLGQPPPPLHTQLYPGPAQDPLPA 1029
Query: 411 HG--------GPPVTAPPPHHYNPNSLPQFTEDQGTLSPPFTQPGGMSPGIWPAPRGPPP 462
H GPP PP Y P T G + P T G S G P
Sbjct: 1030 HSGALPFPSPGPPQPPHPPLAYGP---APSTRPMGPQAAPLTIRGPSSAG------QSTP 1080
Query: 463 PPRLQGPPSQTPLPGPHHP 481
P L P+ +P PGP P
Sbjct: 1081 SPHLVPSPAPSPGPGPVPP 1099
Score = 55.1 bits (131), Expect = 1e-07
Identities = 62/223 (27%), Positives = 84/223 (37%), Gaps = 31/223 (13%)
Query: 272 PPPRSVSQETFRISTRKHSNLITVPIQDDSNSGAREPPPPAPAPAHHHPEYQGQPVVSHP 331
PPPR + + + R+ S + D R PP A + G H
Sbjct: 716 PPPRPTAPKPL-LPRREESEAVEA---GDPPEELRSLPPDMVAGPRLPDTFLGSATPLH- 770
Query: 332 HHIMPPQQHYAPPPPPPPPISHPMPHPPQAAGTPHLVYSQAPPP---PMTSAP-----PP 383
PP + P P +S P+P P +G L+ +AP P P+ P P
Sbjct: 771 ---FPPSPFPSSTGPGPHYLSGPLP-PGTYSGPTQLIQPRAPGPHAMPVAPGPALYPAPA 826
Query: 384 ITPPPGHIIAQMPPYMNHPPP----GPPPPQHGGPPVTAPPPHHYNPN---SLPQFTEDQ 436
TP G + P + P GP PP G P +APPP P ++ T
Sbjct: 827 YTPELGLVPRSSPQHGVVSSPYVGVGPAPPVAGLP--SAPPPQFSGPELAMAVRPATTTV 884
Query: 437 GTLSPPFTQPGGMSPGIWPAPRGPPPPPRLQGPPSQTPLPGPH 479
++ P P +P P P PPPP PP Q PLP P+
Sbjct: 885 DSIQAPI--PSHTAPR--PNPTPAPPPPCFPVPPPQ-PLPTPY 922
Score = 46.6 bits (109), Expect = 5e-05
Identities = 56/216 (25%), Positives = 70/216 (32%), Gaps = 49/216 (22%)
Query: 211 PPPTEIPERFIMP-------PDKHHMSH-IP---------------PKQHIMM---PPPP 244
PPP +P + P P +HH S IP P+ H P PP
Sbjct: 913 PPPQPLPTPYTYPAGAKQPIPAQHHFSSGIPAGFPAPRIGPQPQPHPQPHPSQAFGPQPP 972
Query: 245 LQHVP--HEHYNQPHEDIRAPPAELSMAPPPPRSVSQETFRISTRKHSNLITVPIQDD-- 300
Q +P H H P PP P P + Q + H+ L P QD
Sbjct: 973 QQPLPLQHPHLFPPQAPGLLPPQSPYPYAPQPGVLGQPPPPL----HTQLYPGPAQDPLP 1028
Query: 301 SNSGAREPPPPAPAPAHHHPEYQGQPVVSHPHHIMP---------------PQQHYAPPP 345
++SGA P P P H P G + P P H P P
Sbjct: 1029 AHSGALPFPSPGPPQPPHPPLAYGPAPSTRPMGPQAAPLTIRGPSSAGQSTPSPHLVPSP 1088
Query: 346 PPPPPISHPMPHPPQAAGTPHLVYSQAPPPPMTSAP 381
P P P PP A P L A ++S+P
Sbjct: 1089 APSPGPGPVPPRPPAAEPPPCLRRGAAAADLLSSSP 1124
Score = 35.0 bits (79), Expect = 0.16
Identities = 37/131 (28%), Positives = 42/131 (32%), Gaps = 29/131 (22%)
Query: 374 PPPMTSAPPPITP-----------PPGHIIAQMPPYMNHPPP------GPPPPQHGGP-- 414
PPP +AP P+ P P + +PP M P G P H P
Sbjct: 716 PPPRPTAPKPLLPRREESEAVEAGDPPEELRSLPPDMVAGPRLPDTFLGSATPLHFPPSP 775
Query: 415 -PVTAPPPHHYNPNSLPQFTEDQGTLSPP--FTQPGGMSPGIWPAPRGPP--PPPRLQGP 469
P + P HY LP GT S P QP P P GP P P
Sbjct: 776 FPSSTGPGPHYLSGPLP-----PGTYSGPTQLIQPRAPGPHAMPVAPGPALYPAPAYTPE 830
Query: 470 PSQTPLPGPHH 480
P P H
Sbjct: 831 LGLVPRSSPQH 841
Score = 34.3 bits (77), Expect = 0.26
Identities = 46/162 (28%), Positives = 60/162 (37%), Gaps = 33/162 (20%)
Query: 319 HPEYQGQPVVSHPHHIMPPQQHYAPPPPPPPPISH--PMPHPPQAAGTPHLVYSQAPPPP 376
H + + VV H ++ Q+H PPP P + H PQ + LV P
Sbjct: 1441 HLRFCYEAVVRHVEQVL--QRHGVPPPCKPLASASISQKNHLPQ--DSQDLVLGGDVPIS 1496
Query: 377 M---TSAPPPITPPPGHIIAQMPPYMNHPPPGPPPPQHGGPPVTAPPPHHYNPNSLPQFT 433
T A I PP G P + P P PP G PP SLP+ T
Sbjct: 1497 SIQATIAKLSIRPPGG----LESPVASLPGPAEPP---GLPPA-----------SLPEST 1538
Query: 434 EDQGTLSPPFTQPGGMSPGIWPAPRGPPPPPRL--QGPPSQT 473
+ PP + P + P P+ PP P GPPS +
Sbjct: 1539 PIPSSSPPPLSSPLPEA----PQPKEEPPVPEAPSSGPPSSS 1576
Score = 33.5 bits (75), Expect = 0.45
Identities = 23/76 (30%), Positives = 29/76 (38%), Gaps = 11/76 (14%)
Query: 304 GAREPPPPAPAPAHHHPEYQGQPVVSHPHHIMPPQQHYAPPPPPPPPISHPMPHPPQAAG 363
G P P PA E G P S P P PPP+S P+P PQ
Sbjct: 1512 GLESPVASLPGPA----EPPGLPPASLPESTPIPSSS-------PPPLSSPLPEAPQPKE 1560
Query: 364 TPHLVYSQAPPPPMTS 379
P + + + PP +S
Sbjct: 1561 EPPVPEAPSSGPPSSS 1576
Score = 31.6 bits (70), Expect = 1.7
Identities = 42/170 (24%), Positives = 52/170 (30%), Gaps = 32/170 (18%)
Query: 206 HPPIAPP--PTEIPERFIMP--PDKHHMSHIPPKQHIMMPPPPLQHVPHEHYNQPHEDIR 261
HP + PP P +P + P P + PP H + P P Q H
Sbjct: 980 HPHLFPPQAPGLLPPQSPYPYAPQPGVLGQPPPPLHTQLYPGPAQDPLPAHSGALPFPSP 1039
Query: 262 APPAELSMAPPPPRSVSQETFRISTRKHSNLITVPIQDDSNSGAREPPPPAPAPAHHHPE 321
PP PP P P+ R P A P
Sbjct: 1040 GPP-----QPPHP---------------------PLAYGPAPSTRPMGPQAAPLTIRGPS 1073
Query: 322 YQGQPVVSHPHHIMPPQQHYAP-PPPPPPPISHPMPHPPQAAGTPHLVYS 370
GQ S PH + P P P PP PP + P P + A L+ S
Sbjct: 1074 SAGQSTPS-PHLVPSPAPSPGPGPVPPRPPAAEPPPCLRRGAAAADLLSS 1122
>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
Length = 1012
Score = 82.8 bits (203), Expect = 6e-16
Identities = 97/362 (26%), Positives = 124/362 (34%), Gaps = 79/362 (21%)
Query: 194 GKPVTRASLENVHPPIAPPP-TEIPERFIMPPDKHHMSHIPPKQHIMMPPPPLQHVPHEH 252
G P + P AP P T I + + P + H PP P PPLQ +
Sbjct: 223 GSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPS---PHPPLQPLTGSA 279
Query: 253 YNQPHEDIRAPPAELSMAPPPPRSV---------------------SQETFRISTRK--- 288
QP A P PP P S+ SQ + T
Sbjct: 280 -GQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAA 338
Query: 289 --HSNLITVPIQD--DSNSGAREPP-PPAPAPAHHH--------PEYQGQPVVSHPHHIM 335
H++L Q S RE P PPAP H P+ HP H+
Sbjct: 339 YPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLS 398
Query: 336 PPQQHYAPPPPPPPPISHPMP-----HPPQAAGTPHLVYSQAPPPPMTSAPPP------- 383
P PPPP P+ HPP A P + Q+ P P + A PP
Sbjct: 399 GPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQN 458
Query: 384 ITPPPG-------HIIAQMPPYMNHP--PPGPPPPQHGGPPVTAPPPHHYNPNSLPQFTE 434
+ PPP H +A PP+ HP P GPPP P T+ PP ++ P +
Sbjct: 459 LPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCS- 517
Query: 435 DQGTLSPPFTQPGGMS---PGIW---------PAPRGPPPPPRLQGPPSQTPLPGPHHPD 482
G + + GG S P + P PPPPPR P T + P H
Sbjct: 518 --GAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPR-SPSPEPTVVDTPSHAS 574
Query: 483 QT 484
Q+
Sbjct: 575 QS 576
Score = 70.1 bits (170), Expect = 4e-12
Identities = 78/292 (26%), Positives = 93/292 (31%), Gaps = 70/292 (23%)
Query: 248 VPHEHYNQPHEDIRAPPAELSMAPPPPRSVSQETFRISTRKHSNLITVPIQDDSNSGARE 307
+P N+ D A L PP ++ + T P + G +
Sbjct: 161 IPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVT--------------PAPSSAPPGTPQ 206
Query: 308 PPPPAPAPAHHHPEYQGQPVVS--------------HPHHIMPPQQHYAPPPPPPPPISH 353
P P P P+ QG P S H H P H PP P PP H
Sbjct: 207 LPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPP-PH 265
Query: 354 PMPHPPQAAGTPHLVYSQAPPPPMTSAPPPI--TPPPGHIIAQMPPYMNHPPPGPP---P 408
P PHPP L S P + A PP+ PPG Q P + HP P P P
Sbjct: 266 PSPHPPLQP----LTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLP 321
Query: 409 PQ--HGGPPVTAPPPHHYNPNSLP-----------QFTEDQGTLSPPFTQPGGMSPGIWP 455
PQ G P+ P Y SL Q +Q P P P P
Sbjct: 322 PQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTP 381
Query: 456 APRGPPP-----PPRLQG------------PPSQTPLP--GPHHPDQTRYRP 488
P+ P P PP L G PP+ PL HHP P
Sbjct: 382 IPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPP 433
Score = 48.5 bits (114), Expect = 1e-05
Identities = 60/215 (27%), Positives = 71/215 (33%), Gaps = 36/215 (16%)
Query: 300 DSNSGAREPPPPAPAPAHHHPE---------YQGQPVVSHPHHIMPPQQHYAPPPPPPPP 350
D + R P P+P + + Q QP + P APP P P
Sbjct: 149 DIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLP 208
Query: 351 ISHPMPH----PPQAAGTPHLVYSQAPPPPMTSAPPPITPPPGHIIAQMPPYMNHPPPGP 406
P P PPQ + T SQAP P P P P I Q P PP P
Sbjct: 209 TPGPTPSATAVPPQGSPTA----SQAPNQPQA----PTAPVPHTHIQQAPALHPQRPPSP 260
Query: 407 PPPQHG-----GPPVTAPPPHHYNPNSLPQFTEDQGTLSPPFTQPGGM--SPGIWPAPRG 459
PP H P+T P+ QG P Q G + PG P P G
Sbjct: 261 HPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGP-PQPFG 319
Query: 460 PPPPPRLQGPPSQTPL---PGPHHPDQTRYRPYYQ 491
PP Q Q PL P +P + P Q
Sbjct: 320 LPP----QASQGQAPLGTSPAAAYPHTSLQLPASQ 350
Score = 37.4 bits (85), Expect = 0.031
Identities = 32/101 (31%), Positives = 42/101 (41%), Gaps = 18/101 (17%)
Query: 184 AHIN-HRHMRAGKPVTRASLENVHPPIAPPPTEIPE--RFIMPPDKHHMSHIPPKQHIMM 240
+HI+ H H+ P+ + S VH P+ P T P RF PP +
Sbjct: 876 SHIHSHLHLHQQDPLHQGSAGPVH-PLVDPLTAGPHLARFPYPPG-------------TL 921
Query: 241 PPPPLQHVPHEHYNQPHEDIRAP-PAELSMAPPPPRSVSQE 280
P P L PHEH H P P +L A PPP S + +
Sbjct: 922 PNPLLGQPPHEHEMLRHPVFGTPYPRDLPGAIPPPMSAAHQ 962
>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 82.8 bits (203), Expect = 6e-16
Identities = 97/362 (26%), Positives = 124/362 (34%), Gaps = 79/362 (21%)
Query: 194 GKPVTRASLENVHPPIAPPP-TEIPERFIMPPDKHHMSHIPPKQHIMMPPPPLQHVPHEH 252
G P + P AP P T I + + P + H PP P PPLQ +
Sbjct: 777 GSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPS---PHPPLQPLTGSA 833
Query: 253 YNQPHEDIRAPPAELSMAPPPPRSV---------------------SQETFRISTRK--- 288
QP A P PP P S+ SQ + T
Sbjct: 834 -GQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAA 892
Query: 289 --HSNLITVPIQD--DSNSGAREPP-PPAPAPAHHH--------PEYQGQPVVSHPHHIM 335
H++L Q S RE P PPAP H P+ HP H+
Sbjct: 893 YPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLS 952
Query: 336 PPQQHYAPPPPPPPPISHPMP-----HPPQAAGTPHLVYSQAPPPPMTSAPPP------- 383
P PPPP P+ HPP A P + Q+ P P + A PP
Sbjct: 953 GPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQN 1012
Query: 384 ITPPPG-------HIIAQMPPYMNHP--PPGPPPPQHGGPPVTAPPPHHYNPNSLPQFTE 434
+ PPP H +A PP+ HP P GPPP P T+ PP ++ P +
Sbjct: 1013 LPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCS- 1071
Query: 435 DQGTLSPPFTQPGGMS---PGIW---------PAPRGPPPPPRLQGPPSQTPLPGPHHPD 482
G + + GG S P + P PPPPPR P T + P H
Sbjct: 1072 --GAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPR-SPSPEPTVVDTPSHAS 1128
Query: 483 QT 484
Q+
Sbjct: 1129 QS 1130
Score = 70.1 bits (170), Expect = 4e-12
Identities = 78/292 (26%), Positives = 93/292 (31%), Gaps = 70/292 (23%)
Query: 248 VPHEHYNQPHEDIRAPPAELSMAPPPPRSVSQETFRISTRKHSNLITVPIQDDSNSGARE 307
+P N+ D A L PP ++ + T P + G +
Sbjct: 715 IPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVT--------------PAPSSAPPGTPQ 760
Query: 308 PPPPAPAPAHHHPEYQGQPVVS--------------HPHHIMPPQQHYAPPPPPPPPISH 353
P P P P+ QG P S H H P H PP P PP H
Sbjct: 761 LPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPP-PH 819
Query: 354 PMPHPPQAAGTPHLVYSQAPPPPMTSAPPPI--TPPPGHIIAQMPPYMNHPPPGPP---P 408
P PHPP L S P + A PP+ PPG Q P + HP P P P
Sbjct: 820 PSPHPPLQP----LTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLP 875
Query: 409 PQ--HGGPPVTAPPPHHYNPNSLP-----------QFTEDQGTLSPPFTQPGGMSPGIWP 455
PQ G P+ P Y SL Q +Q P P P P
Sbjct: 876 PQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTP 935
Query: 456 APRGPPP-----PPRLQG------------PPSQTPLP--GPHHPDQTRYRP 488
P+ P P PP L G PP+ PL HHP P
Sbjct: 936 IPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPP 987
Score = 48.5 bits (114), Expect = 1e-05
Identities = 60/215 (27%), Positives = 71/215 (33%), Gaps = 36/215 (16%)
Query: 300 DSNSGAREPPPPAPAPAHHHPE---------YQGQPVVSHPHHIMPPQQHYAPPPPPPPP 350
D + R P P+P + + Q QP + P APP P P
Sbjct: 703 DIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLP 762
Query: 351 ISHPMPH----PPQAAGTPHLVYSQAPPPPMTSAPPPITPPPGHIIAQMPPYMNHPPPGP 406
P P PPQ + T SQAP P P P P I Q P PP P
Sbjct: 763 TPGPTPSATAVPPQGSPTA----SQAPNQPQA----PTAPVPHTHIQQAPALHPQRPPSP 814
Query: 407 PPPQHG-----GPPVTAPPPHHYNPNSLPQFTEDQGTLSPPFTQPGGM--SPGIWPAPRG 459
PP H P+T P+ QG P Q G + PG P P G
Sbjct: 815 HPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGP-PQPFG 873
Query: 460 PPPPPRLQGPPSQTPL---PGPHHPDQTRYRPYYQ 491
PP Q Q PL P +P + P Q
Sbjct: 874 LPP----QASQGQAPLGTSPAAAYPHTSLQLPASQ 904
Score = 37.4 bits (85), Expect = 0.031
Identities = 32/101 (31%), Positives = 42/101 (41%), Gaps = 18/101 (17%)
Query: 184 AHIN-HRHMRAGKPVTRASLENVHPPIAPPPTEIPE--RFIMPPDKHHMSHIPPKQHIMM 240
+HI+ H H+ P+ + S VH P+ P T P RF PP +
Sbjct: 1430 SHIHSHLHLHQQDPLHQGSAGPVH-PLVDPLTAGPHLARFPYPPG-------------TL 1475
Query: 241 PPPPLQHVPHEHYNQPHEDIRAP-PAELSMAPPPPRSVSQE 280
P P L PHEH H P P +L A PPP S + +
Sbjct: 1476 PNPLLGQPPHEHEMLRHPVFGTPYPRDLPGAIPPPMSAAHQ 1516
>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 82.8 bits (203), Expect = 6e-16
Identities = 97/362 (26%), Positives = 124/362 (34%), Gaps = 79/362 (21%)
Query: 194 GKPVTRASLENVHPPIAPPP-TEIPERFIMPPDKHHMSHIPPKQHIMMPPPPLQHVPHEH 252
G P + P AP P T I + + P + H PP P PPLQ +
Sbjct: 777 GSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPS---PHPPLQPLTGSA 833
Query: 253 YNQPHEDIRAPPAELSMAPPPPRSV---------------------SQETFRISTRK--- 288
QP A P PP P S+ SQ + T
Sbjct: 834 -GQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAA 892
Query: 289 --HSNLITVPIQD--DSNSGAREPP-PPAPAPAHHH--------PEYQGQPVVSHPHHIM 335
H++L Q S RE P PPAP H P+ HP H+
Sbjct: 893 YPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLS 952
Query: 336 PPQQHYAPPPPPPPPISHPMP-----HPPQAAGTPHLVYSQAPPPPMTSAPPP------- 383
P PPPP P+ HPP A P + Q+ P P + A PP
Sbjct: 953 GPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQN 1012
Query: 384 ITPPPG-------HIIAQMPPYMNHP--PPGPPPPQHGGPPVTAPPPHHYNPNSLPQFTE 434
+ PPP H +A PP+ HP P GPPP P T+ PP ++ P +
Sbjct: 1013 LPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCS- 1071
Query: 435 DQGTLSPPFTQPGGMS---PGIW---------PAPRGPPPPPRLQGPPSQTPLPGPHHPD 482
G + + GG S P + P PPPPPR P T + P H
Sbjct: 1072 --GAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPR-SPSPEPTVVDTPSHAS 1128
Query: 483 QT 484
Q+
Sbjct: 1129 QS 1130
Score = 70.1 bits (170), Expect = 4e-12
Identities = 78/292 (26%), Positives = 93/292 (31%), Gaps = 70/292 (23%)
Query: 248 VPHEHYNQPHEDIRAPPAELSMAPPPPRSVSQETFRISTRKHSNLITVPIQDDSNSGARE 307
+P N+ D A L PP ++ + T P + G +
Sbjct: 715 IPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVT--------------PAPSSAPPGTPQ 760
Query: 308 PPPPAPAPAHHHPEYQGQPVVS--------------HPHHIMPPQQHYAPPPPPPPPISH 353
P P P P+ QG P S H H P H PP P PP H
Sbjct: 761 LPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPP-PH 819
Query: 354 PMPHPPQAAGTPHLVYSQAPPPPMTSAPPPI--TPPPGHIIAQMPPYMNHPPPGPP---P 408
P PHPP L S P + A PP+ PPG Q P + HP P P P
Sbjct: 820 PSPHPPLQP----LTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLP 875
Query: 409 PQ--HGGPPVTAPPPHHYNPNSLP-----------QFTEDQGTLSPPFTQPGGMSPGIWP 455
PQ G P+ P Y SL Q +Q P P P P
Sbjct: 876 PQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTP 935
Query: 456 APRGPPP-----PPRLQG------------PPSQTPLP--GPHHPDQTRYRP 488
P+ P P PP L G PP+ PL HHP P
Sbjct: 936 IPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPP 987
Score = 48.5 bits (114), Expect = 1e-05
Identities = 60/215 (27%), Positives = 71/215 (33%), Gaps = 36/215 (16%)
Query: 300 DSNSGAREPPPPAPAPAHHHPE---------YQGQPVVSHPHHIMPPQQHYAPPPPPPPP 350
D + R P P+P + + Q QP + P APP P P
Sbjct: 703 DIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLP 762
Query: 351 ISHPMPH----PPQAAGTPHLVYSQAPPPPMTSAPPPITPPPGHIIAQMPPYMNHPPPGP 406
P P PPQ + T SQAP P P P P I Q P PP P
Sbjct: 763 TPGPTPSATAVPPQGSPTA----SQAPNQPQA----PTAPVPHTHIQQAPALHPQRPPSP 814
Query: 407 PPPQHG-----GPPVTAPPPHHYNPNSLPQFTEDQGTLSPPFTQPGGM--SPGIWPAPRG 459
PP H P+T P+ QG P Q G + PG P P G
Sbjct: 815 HPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGP-PQPFG 873
Query: 460 PPPPPRLQGPPSQTPL---PGPHHPDQTRYRPYYQ 491
PP Q Q PL P +P + P Q
Sbjct: 874 LPP----QASQGQAPLGTSPAAAYPHTSLQLPASQ 904
Score = 37.4 bits (85), Expect = 0.031
Identities = 32/101 (31%), Positives = 42/101 (41%), Gaps = 18/101 (17%)
Query: 184 AHIN-HRHMRAGKPVTRASLENVHPPIAPPPTEIPE--RFIMPPDKHHMSHIPPKQHIMM 240
+HI+ H H+ P+ + S VH P+ P T P RF PP +
Sbjct: 1430 SHIHSHLHLHQQDPLHQGSAGPVH-PLVDPLTAGPHLARFPYPPG-------------TL 1475
Query: 241 PPPPLQHVPHEHYNQPHEDIRAP-PAELSMAPPPPRSVSQE 280
P P L PHEH H P P +L A PPP S + +
Sbjct: 1476 PNPLLGQPPHEHEMLRHPVFGTPYPRDLPGAIPPPMSAAHQ 1516
>gi|47132519 Ras association and pleckstrin homology domains 1
isoform 1 [Homo sapiens]
Length = 1250
Score = 82.4 bits (202), Expect = 8e-16
Identities = 84/298 (28%), Positives = 108/298 (36%), Gaps = 35/298 (11%)
Query: 207 PPIAPPPTEIPERFIMPPDKHHMSHIPPKQHIMMPPPPLQHVPHEHYNQPHEDIRAPPAE 266
PP PPPT + P P PPPPL+ +H Q PP
Sbjct: 713 PPPPPPPTPGSAMAQLKP----APCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPP 768
Query: 267 LSMAPPPPRSVSQETFRISTRKHSNLITVPIQDDSNSGAREPPPPA---PA-PAHHHPEY 322
+ AP PP++ + I + + + + P PPA PA PA + P
Sbjct: 769 IP-APLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPS 827
Query: 323 QGQPVVSHPHHIMPPQQHYAPPPPPPPPISHPMPHPPQAAGTPHLVYSQAPPPPMTSA-- 380
P V P +P QQ + PPP P P+P + + SQ PPPP A
Sbjct: 828 PPTPPVPVPPPTLPKQQSFCAKPPPSP--LSPVPSVVKQ------IASQFPPPPTPPAME 879
Query: 381 PPPITPPPGHIIAQMPPYMNHPP---------PGP--PPPQHGGPPVTAPPPHHYNPNSL 429
P+ P P ++ Q PP + P P P PPP V PPP P
Sbjct: 880 SQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPP 939
Query: 430 PQFTEDQGTLSPPFTQPG--GMSPGIWPAPRGPPPPPRLQGPPSQTPLPGPHHPDQTR 485
P T SP + G G +P G PPP Q S G HP+ R
Sbjct: 940 PP---PPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKR 994
Score = 81.3 bits (199), Expect = 2e-15
Identities = 80/301 (26%), Positives = 106/301 (35%), Gaps = 59/301 (19%)
Query: 207 PPIAPPPTEIPERFIMPPDKHHMSHIPPKQHIMMPPPPLQHVPHEHYNQPHEDIRAPPAE 266
PP+ + P+ ++PP+ +PP PPPP P Q AP
Sbjct: 689 PPVMQSQSVKPQ-ILVPPN----GVVPPP-----PPPPPPPTPGSAMAQLKPAPCAPSLP 738
Query: 267 LSMAPPPPRSVSQETFRISTRKHSNLITVPIQDDSNSGAREPPPPAPAPAHHHPEYQGQP 326
APPPP + Q +H + P PPPP P PA P+ +P
Sbjct: 739 QFSAPPPPLKIHQV-------QHITQVAPPT----------PPPPPPIPAPLPPQAPPKP 781
Query: 327 VVSHPH----HIMPPQQHYAPPPPPPPPISHPMPHPPQAAGTPHLVYSQAPPPPMTSAPP 382
+V+ P + P A PP P PP+ P + P +PP P PP
Sbjct: 782 LVTIPAPTSTKTVAPVVTQAAPPTPTPPV----PPAKKQPAFPASYIPPSPPTPPVPVPP 837
Query: 383 PITPPPGHIIAQMPPYMNHP------------PPGPPPPQHGGPPVTAPPPHHYNPNSLP 430
P P A+ PP P PP P PP P+ P P + P S P
Sbjct: 838 PTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLK-PVPANVAPQSPP 896
Query: 431 QFTEDQG-------TLSPPFTQPGGMSPGIWPAPRGPPPPPRLQGPPSQTPLPGPHHPDQ 483
SP F P S ++P PPPP + PP P PD+
Sbjct: 897 AVKAKPKWQPSSIPVPSPDFPPPPPESSLVFP----PPPPSPVPAPPPPPPPTASPTPDK 952
Query: 484 T 484
+
Sbjct: 953 S 953
Score = 80.9 bits (198), Expect = 2e-15
Identities = 98/360 (27%), Positives = 122/360 (33%), Gaps = 105/360 (29%)
Query: 195 KPVTRASLENVHPPIAPPPTEIPERFIMPPDKHHMSHIPPKQHIMMPPPPLQHVPHEHYN 254
K VT + PP+ PPP P PP PP PPPP +P +
Sbjct: 614 KIVTPYTASQPSPPLPPPPPPPPP----PP--------PP------PPPPPPPLPSQS-- 653
Query: 255 QPHEDIRAPPAELSMAPPPPRSVSQETFRISTRKHSNLI----TVPIQDDSN-------- 302
AP A A P S T + +HS + T P+ +
Sbjct: 654 -------APSA--GSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVP 704
Query: 303 -SGAREPPPPAPAP---------------AHHHPEYQGQPVVSHPHHIMPPQQHYAPPPP 346
+G PPPP P P A P++ P H + Q P PP
Sbjct: 705 PNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPP 764
Query: 347 PPPPISHPMPHPPQAAGTPHL-------------VYSQAPPPPMTSAPPPITPPPGHIIA 393
PPPPI P P PPQA P + V +QA PP T PP P +
Sbjct: 765 PPPPI--PAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPAS 822
Query: 394 QMPPYMNHPP-PGPPP---------------PQHGGPPVTAPPPHHYNPNSLPQFTEDQG 437
+PP PP P PPP P P V + P P E Q
Sbjct: 823 YIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQ- 881
Query: 438 TLSP------PFTQPGGMSPGIW-------PAPRGPPPPPR---LQGPPSQTPLPGPHHP 481
L P P + P + W P+P PPPPP + PP +P+P P P
Sbjct: 882 PLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPP 941
Score = 70.5 bits (171), Expect = 3e-12
Identities = 97/341 (28%), Positives = 121/341 (35%), Gaps = 73/341 (21%)
Query: 202 LENVHPPIAPPPTEIP---------ERFIMPPDKHHMSHIPPKQHIMMPPPPLQHVPHEH 252
+ V PP PPP IP + + P + P PP P VP
Sbjct: 755 ITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAK 814
Query: 253 YNQ--PHEDIRAPPAELSMAPPPPRSVSQETFRISTRKHSNLITVP--IQDDSNSGAREP 308
P I P + PPP Q++F + S L VP ++ ++ P
Sbjct: 815 KQPAFPASYIPPSPPTPPVPVPPPTLPKQQSF-CAKPPPSPLSPVPSVVKQIASQFPPPP 873
Query: 309 PPPA-------PAPAHHHPEYQGQPVVS-----HPHHIMPPQQHYAPPPP------PPPP 350
PPA P PA+ P Q P V P I P + PPPP PPPP
Sbjct: 874 TPPAMESQPLKPVPANVAP--QSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPP 931
Query: 351 ISH----PMPHPPQAAGTPHLVYSQAPPPPMTSAP----PPITPPPGHIIAQMPPYMNHP 402
S P P PP A+ TP S TS+P PP TP I HP
Sbjct: 932 PSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSG-AEHP 990
Query: 403 PPGPP----------PPQHGG--------PPVTAPPPHHYNPN--SLPQFTEDQGTLS-- 440
P P PP G PP P P N + +LP + QG +S
Sbjct: 991 EPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQ-QGCVSAK 1049
Query: 441 -PPFTQPGGMSPGIWPAPRG----PPPPPR--LQGPPSQTP 474
P + G S +P+P PPPPP L PP + P
Sbjct: 1050 APVLSGRGKDSVVEFPSPPSDSDFPPPPPETELPLPPIEIP 1090
Score = 67.4 bits (163), Expect = 3e-11
Identities = 57/186 (30%), Positives = 70/186 (37%), Gaps = 34/186 (18%)
Query: 309 PPPAPAPAHHHPEYQGQPVVSHPHHIMPPQQHYAPPPPPPPPISHPMPHPPQAAGTPHLV 368
PP +P P P QP P PP PPPPPPPP+ +A +
Sbjct: 607 PPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVK 666
Query: 369 YS----------------QAPPPPM---TSAPPPITPPPGHIIAQMPPYMNHPPPGPPPP 409
YS + P PP+ S P I PP ++ PPP PPPP
Sbjct: 667 YSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVP--------PPPPPPPP 718
Query: 410 QHGGPPVTAPPPHHYNPNSLPQFTEDQGTLSPPFTQPGGMSPGIWPAPRGPPPPPRLQGP 469
G + P P SLPQF + PP + + AP PPPPP + P
Sbjct: 719 PTPGSAMAQLKPAPCAP-SLPQF-----SAPPPPLKIHQVQHITQVAPPTPPPPPPIPAP 772
Query: 470 -PSQTP 474
P Q P
Sbjct: 773 LPPQAP 778
Score = 55.1 bits (131), Expect = 1e-07
Identities = 39/125 (31%), Positives = 50/125 (40%), Gaps = 26/125 (20%)
Query: 376 PMTSAPPPITPPP----GHIIAQMPPYMNHPPPGPPPPQHGGPPVTAPPPHHYNPNS--- 428
P TS PP++P P + +Q P + PPP PPPP PP P P P++
Sbjct: 601 PYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSA 660
Query: 429 ------------LPQFTEDQGTL----SPPFTQPGGMSPGIWPAPRGPPPPPRLQGPPSQ 472
L ++ G L +PP Q + P I P G PPP PP
Sbjct: 661 APMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPP---PPPPP 717
Query: 473 TPLPG 477
P PG
Sbjct: 718 PPTPG 722
Score = 44.7 bits (104), Expect = 2e-04
Identities = 66/282 (23%), Positives = 86/282 (30%), Gaps = 88/282 (31%)
Query: 207 PPIAPPPTEIPERFIMPPDKHHMSHIPPKQHIMMPPPPLQHVPHEHYNQPHEDIRAPPAE 266
P P +P PP PP+ ++ PPPP VP APP
Sbjct: 902 PKWQPSSIPVPSPDFPPP--------PPESSLVFPPPPPSPVP------------APP-- 939
Query: 267 LSMAPPPPRSVSQETFRISTRKHSNLITVPIQDDSNSGAREPPPPAP-------APAHHH 319
PPPP + S T S S+ G ++PPP + H
Sbjct: 940 ----PPPPPTASP------TPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEH 989
Query: 320 PEYQGQPVVSHPHHIMPPQQHYAP-----PPPPPPP---------ISHP----------- 354
PE + V S PP + +P PPP PP ++ P
Sbjct: 990 PEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAK 1049
Query: 355 --------------MPHPPQAAGTPHLVYSQAPPPPMTSAPPPITPPPGHIIAQMPPYMN 400
P PP + P PPPP T P P P P +
Sbjct: 1050 APVLSGRGKDSVVEFPSPPSDSDFP-------PPPPETELPLPPIEIPAVFSGNTSPKV- 1101
Query: 401 HPPPGPPPPQHGGPPV-TAPPPHHYNPNSLPQFTEDQGTLSP 441
P P Q V APPP N + T+ + + P
Sbjct: 1102 -AVVNPQPQQWSKMSVKKAPPPTRPKRNDSTRLTQAEISEQP 1142
Score = 33.9 bits (76), Expect = 0.35
Identities = 23/77 (29%), Positives = 27/77 (35%), Gaps = 13/77 (16%)
Query: 414 PPVTAPPPHHYNPNSLPQFTEDQGTLSPPFTQPGGMSPGIWPAPRGPPPPPRLQGPPSQT 473
P + PP P + +T Q SPP P P PPPPP PP
Sbjct: 601 PYTSLVPPLSPQPKIVTPYTASQP--SPPL-----------PPPPPPPPPPPPPPPPPPP 647
Query: 474 PLPGPHHPDQTRYRPYY 490
PLP P P +
Sbjct: 648 PLPSQSAPSAGSAAPMF 664
>gi|37537692 proline-rich protein BstNI subfamily 4 precursor [Homo
sapiens]
Length = 247
Score = 81.6 bits (200), Expect = 1e-15
Identities = 74/237 (31%), Positives = 89/237 (37%), Gaps = 44/237 (18%)
Query: 267 LSMAPPPPRSVSQET--FRISTRKHSNLITVPIQDDSNSGAREPPPPAPAPAHHHPEYQG 324
LS A VSQE F IS + + + + PPPP P QG
Sbjct: 13 LSSAESSSEDVSQEESLFLISGKPEGR------RPQGGNQPQRPPPPPGKP-------QG 59
Query: 325 QPVVSHPHHIMPPQ---QHYAPPPPPPPPISHPMPHPPQAAGTPHLVYSQAPPPPMTSAP 381
P PQ Q PPPPP P P Q+ G P PPP
Sbjct: 60 PP----------PQGGNQSQGPPPPPGKPEGRPPQGGNQSQGPPPHPGKPERPPPQGGNQ 109
Query: 382 PPITPPPGHIIAQMPPY---MNHPPPGPP-----PPQHGGPPVTAPPPHHYNPNSLP--Q 431
TPPP + PP +H PP PP PP GG PPPH P P +
Sbjct: 110 SQGTPPPPGKPERPPPQGGNQSHRPPPPPGKPERPPPQGGNQSQGPPPHPGKPEGPPPQE 169
Query: 432 FTEDQGTLSPPFTQPGGMSPGIWPAPRGPPPPPRLQGPPSQTPLPGPHHPDQTRYRP 488
+ + SPP +P G P+GPPPP + QGPP P +P Q + P
Sbjct: 170 GNKSRSARSPP-GKPQGPPQQEGNKPQGPPPPGKPQGPP-----PAGGNPQQPQAPP 220
Score = 55.1 bits (131), Expect = 1e-07
Identities = 65/240 (27%), Positives = 73/240 (30%), Gaps = 53/240 (22%)
Query: 193 AGKPVTRASLENVHPPIAPPPTEIPERFIMPPDKHHMSHIPPKQHIMMPPPPLQHVPHEH 252
+GKP R P PPP P+ PP + S PP PP + P +
Sbjct: 33 SGKPEGRRPQGGNQPQRPPPPPGKPQG--PPPQGGNQSQGPPP-----PPGKPEGRPPQG 85
Query: 253 YNQPHEDIRAPPAELSMAPPPPRSVSQETFRISTRKHSNLITVPIQDDSNSGAREPPPPA 312
NQ S PPP H P N PPPP
Sbjct: 86 GNQ------------SQGPPP---------------HPGKPERPPPQGGNQSQGTPPPPG 118
Query: 313 ----PAPAHHHPEYQGQPVVSHPHHIMPPQQHYAPPPPPPPPISHPMPHPPQAAGTPHLV 368
P P + ++ P P PP Q PPP P PPQ
Sbjct: 119 KPERPPPQGGNQSHRPPPPPGKPER--PPPQGGNQSQGPPPHPGKPEGPPPQEGNKSRSA 176
Query: 369 YS-----QAPPPP---MTSAPPPITPPPGHIIAQMPPYMNHPPP-----GPPPPQHGGPP 415
S Q PP PPP P G A P PP GPPPP GG P
Sbjct: 177 RSPPGKPQGPPQQEGNKPQGPPPPGKPQGPPPAGGNPQQPQAPPAGKPQGPPPPPQGGRP 236
Score = 45.1 bits (105), Expect = 2e-04
Identities = 47/160 (29%), Positives = 55/160 (34%), Gaps = 32/160 (20%)
Query: 211 PPPTEIPERFIMPPDKHHMSHIPPKQHIMMPPPPLQHVPHEHYNQPHEDIRAPPAELSMA 270
PPP PER PP + SH PP PP + P + NQ PP
Sbjct: 114 PPPPGKPER--PPPQGGNQSHRPPP-----PPGKPERPPPQGGNQSQGP---PPHPGKPE 163
Query: 271 PPPPRSVSQETFRISTRKHSNLITVPIQDDSNSGAREPPPPAPAPAHHHPEYQGQPVVSH 330
PPP+ ++ S R P Q + N + PP P P G
Sbjct: 164 GPPPQEGNKSR---SARSPPGKPQGPPQQEGN---KPQGPPPPGKPQGPPPAGGN----- 212
Query: 331 PHHIMPPQQHYAPPP-----PPPPPISHPMPHPPQAAGTP 365
PQQ APP PPPPP P P Q P
Sbjct: 213 ------PQQPQAPPAGKPQGPPPPPQGGRPPRPAQGQQPP 246
>gi|116284392 mucin 2 precursor [Homo sapiens]
Length = 5179
Score = 81.3 bits (199), Expect = 2e-15
Identities = 89/323 (27%), Positives = 102/323 (31%), Gaps = 70/323 (21%)
Query: 207 PPIA----PPPTEIPERFIMPPDKHHMSHIPPKQHIMMPPPPLQHVPHEHYNQPHEDIRA 262
PPI+ PPPT P P + PP PPP P P
Sbjct: 1456 PPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSP------PTTTPIT 1509
Query: 263 PPAELSMAPP---PPRSVSQETFRISTRKHSNLITVPIQDDSNSGAREPPPPAPAPAHHH 319
PPA + PP P + T T S T PI + S PP P+P
Sbjct: 1510 PPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPT-STTTLPPTTTPSP---- 1564
Query: 320 PEYQGQPVVSHPHHIMPPQQHYAPPP---PPPPPISHPMP-------HPPQAAGTPHLVY 369
PP PPP P PP + P P PP +P
Sbjct: 1565 ----------------PPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTT 1608
Query: 370 SQAPPPPMTSAPP---PITPPPGHIIAQMPPYMNHPPP-----GPPPPQHGGPPVTAPPP 421
+ PPP T +PP PITPP +PP PP PPP PP T P
Sbjct: 1609 TTTPPPTTTPSPPTTTPITPPTS--TTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPS 1666
Query: 422 HHYNPNSLPQFTEDQG-----TLSPPFTQPGGMSPGIWP-----------APRGPPPPPR 465
+ P T T SPP T SP P + P PPP
Sbjct: 1667 PPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPT 1726
Query: 466 LQGPPSQTPLPGPHHPDQTRYRP 488
PS T P P T P
Sbjct: 1727 TMTTPSPTTTPSPPTTTMTTLPP 1749
Score = 74.7 bits (182), Expect = 2e-13
Identities = 64/255 (25%), Positives = 75/255 (29%), Gaps = 13/255 (5%)
Query: 233 PPKQHIMMPPPPLQHVPHEHYNQPHEDIRAPPAELSMAPPPPRSVSQETFRISTRKHSNL 292
PP +PP P P P + PPP + +T
Sbjct: 1409 PPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPISTTTTPPPTT 1468
Query: 293 ITVPIQDDSNSGAREPPPPAPAPAHHHPEYQGQPVVSHPHHIMPPQQHYAPPP--PPPPP 350
P + P PP P P + P I PP PP P PP
Sbjct: 1469 TPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTP--ITPPASTTTLPPTTTPSPP 1526
Query: 351 ISHPMPHPPQAAGTPHLVYSQAPPPPMTSAPPPITPPPGHIIAQMPPYMNHPPP----GP 406
+ PP +P PP T+ PP TP P PP P P P
Sbjct: 1527 TTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTP 1586
Query: 407 PPP---QHGGPPVTAPPPHHYNPNSLPQFTEDQGTLSPPFTQPGGMSPGIWPAPRGPPPP 463
PP PP T P P + P T + P T P S P P PP
Sbjct: 1587 SPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPP--TSTTTLPPTTTPSPP 1644
Query: 464 PRLQGPPSQTPLPGP 478
P P T P P
Sbjct: 1645 PTTTTTPPPTTTPSP 1659
Score = 70.1 bits (170), Expect = 4e-12
Identities = 56/182 (30%), Positives = 67/182 (36%), Gaps = 25/182 (13%)
Query: 308 PPPPAPAPAHHHPEYQGQPVVSHPHHIMPPQQHYAPPPP---PPPPISHPMPHPPQAAGT 364
P PP P+ P + P PP PPP P PPI+ PP +
Sbjct: 1399 PSPPTTTPSPPPTSTTTLPPTTTPS---PPTTTTTTPPPTTTPSPPITTTTTPPPTTTPS 1455
Query: 365 PHLVYSQAPPPPMTSAPPPITPPPGHIIAQMPPYMNHPP----PGPPPPQHGGPPVTAPP 420
P + + PPP T +PP TP P P PP PPP PP T P
Sbjct: 1456 PPISTTTTPPPTTTPSPPTTTPSP-------PTTTPSPPTTTTTTPPPTTTPSPPTTTPI 1508
Query: 421 PHHYNPNSLPQFTEDQGTLSPPFTQPGGMSPGIWPAPRG----PPPPPRLQGPPSQTPLP 476
+ +LP T T SPP T P P+P PP PP+ TP P
Sbjct: 1509 TPPASTTTLPPTT----TPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSP 1564
Query: 477 GP 478
P
Sbjct: 1565 PP 1566
Score = 64.7 bits (156), Expect = 2e-10
Identities = 66/268 (24%), Positives = 84/268 (31%), Gaps = 35/268 (13%)
Query: 207 PPIAPPPTEIPERFIMPPDKHHMSHIPPKQHIMMPPPPLQHVPHEHYNQPHEDIRAPPAE 266
PP P T +PP + PP PPP P P +PP
Sbjct: 1541 PPTTTPITPPTSTTTLPPTT---TPSPPPTTTTTPPPTTTPSP------PTTTTPSPPTI 1591
Query: 267 LSMAPPPPRSVSQETFRISTRKHSNL----ITVPIQDDSNSGAREPPPPAPAPAHHHPEY 322
+ PPP + S T +T + T PI +++ PP P+P
Sbjct: 1592 TTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTL-PPTTTPSPP------ 1644
Query: 323 QGQPVVSHPHHIMPPQQHYAPPPP----PPPPISHPMPHPPQAAGTPHLVYSQAPPPPMT 378
P P P PP P PPI+ PP + + + +PP
Sbjct: 1645 --------PTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTM 1696
Query: 379 SAPPPITPPPGHIIAQMPPYMNHPPPGPPPPQHGGPPVTAPPPHHYNPNSLPQFTEDQ-- 436
+ P P T P I P P PP P T P P +LP T
Sbjct: 1697 TTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPPTTTSSPL 1756
Query: 437 -GTLSPPFTQPGGMSPGIWPAPRGPPPP 463
T PP P SP P P P
Sbjct: 1757 TTTPLPPSITPPTFSPFSTTTPTTPCVP 1784
Score = 63.9 bits (154), Expect = 3e-10
Identities = 68/271 (25%), Positives = 91/271 (33%), Gaps = 38/271 (14%)
Query: 211 PPPTEIPERFIMPPDKHHMSHIPPKQHIMMPPPPLQHVPHEHYNQPHEDIRAPPAELSMA 270
PPPT P PP ++ PP +PP + P PP + +
Sbjct: 1533 PPPTTTPS----PPTTTPIT--PPTSTTTLPPTTTP-------SPPPTTTTTPPPTTTPS 1579
Query: 271 PPPPRSVSQETFRISTRKHSNLITVPIQDDSNSGAREPPPPAPAPAHHHPEYQGQPVVSH 330
PP + S T +T + + P + PPP P+ P +
Sbjct: 1580 PPTTTTPSPPTITTTTPPPTTTPSPPTTTTTT------PPPTTTPS---------PPTTT 1624
Query: 331 PHHIMPPQQHYAPPP---PPPPPISHPMPHPPQAAGTPHLVYSQAPPPPMTSAPPPITPP 387
P I PP PP P PPP + P PP +P + +PP T+ PPP T P
Sbjct: 1625 P--ITPPTSTTTLPPTTTPSPPPTTTTTP-PPTTTPSPPTTTTPSPPITTTTTPPPTTTP 1681
Query: 388 PGHIIAQ-MPPYMNHPPPGPPPPQHGGPPVTAPPPHHYNPNSLPQFTEDQG---TLSPPF 443
I PP P P T P P+ P T SPP
Sbjct: 1682 SSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPT 1741
Query: 444 TQPGGMSPGIWPAPRGPPPPPRLQGPPSQTP 474
T + P +P P P PP+ +P
Sbjct: 1742 TTMTTLPPTTTSSPLTTTPLPPSITPPTFSP 1772
Score = 36.6 bits (83), Expect = 0.053
Identities = 39/158 (24%), Positives = 52/158 (32%), Gaps = 29/158 (18%)
Query: 346 PPPPPISHPMPHPPQAAGTPHLVYSQAPPPPMTSAP-------PPITPPPGHIIAQMPPY 398
P P P P + P + + PPP +S P P+T +++ +PP
Sbjct: 4186 PTPTPTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTEST-TLLSTLPPA 4244
Query: 399 MNHPPPGPP-----PPQHGGPPVTAPPPHHYNPNSLPQFTEDQGTLSPPFTQPGGMSPG- 452
+ PP P G +PPP T SPP T G + G
Sbjct: 4245 IEMTSTAPPSTPTAPTTTSGGHTLSPPP--------------STTTSPPGTPTRGTTTGS 4290
Query: 453 -IWPAPRGPPPPPRLQGPPSQTPLPGPHHPDQTRYRPY 489
P P P+ TPL P T RPY
Sbjct: 4291 SSAPTPSTVQTTTTSAWTPTPTPLSTPSIIRTTGLRPY 4328
Score = 35.4 bits (80), Expect = 0.12
Identities = 36/136 (26%), Positives = 50/136 (36%), Gaps = 20/136 (14%)
Query: 256 PHEDIRAPPAELSMAPPPPRSVSQETFRIS----TRKHSNLITVPIQDDSNSGAREPPPP 311
P AP AEL+ + PPP S + +T R + T + L T+P + S A P
Sbjct: 4198 PTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPT 4257
Query: 312 APAPAHHHPEYQGQPVVSHPHHIMPPQQHYAPPPPPPPPISHPMPHPPQAAGTPHLVYSQ 371
AP S H + PP PP P + +A TP V +
Sbjct: 4258 APT------------TTSGGHTLSPPPSTTTSPPGTP---TRGTTTGSSSAPTPSTVQT- 4301
Query: 372 APPPPMTSAPPPITPP 387
T P P++ P
Sbjct: 4302 TTTSAWTPTPTPLSTP 4317
Score = 32.7 bits (73), Expect = 0.77
Identities = 32/136 (23%), Positives = 42/136 (30%), Gaps = 4/136 (2%)
Query: 347 PPPPISHPMPHPPQAAGTPHLVYSQAPPPPMTSAPPPITPPPGHIIAQMP---PYMNHPP 403
P PP + P+ TP +Q P + +TP P Q P P
Sbjct: 1893 PTPPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 1952
Query: 404 PGP-PPPQHGGPPVTAPPPHHYNPNSLPQFTEDQGTLSPPFTQPGGMSPGIWPAPRGPPP 462
P P P P T P P T Q + P T ++P P P
Sbjct: 1953 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2012
Query: 463 PPRLQGPPSQTPLPGP 478
+ + TP P P
Sbjct: 2013 TTPITTTTTVTPTPTP 2028
Score = 31.6 bits (70), Expect = 1.7
Identities = 25/84 (29%), Positives = 30/84 (35%), Gaps = 9/84 (10%)
Query: 414 PPVTAPPPHHYNPNSLPQFTEDQG-----TLSPPFTQPG-GMSPGIWPAPRGPPPPP--- 464
PP T P P + +LP T T PP T P ++ P P P PP
Sbjct: 1401 PPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPIST 1460
Query: 465 RLQGPPSQTPLPGPHHPDQTRYRP 488
PP+ TP P P P
Sbjct: 1461 TTTPPPTTTPSPPTTTPSPPTTTP 1484
>gi|4507909 Wiskott-Aldrich syndrome protein [Homo sapiens]
Length = 502
Score = 79.7 bits (195), Expect = 5e-15
Identities = 52/139 (37%), Positives = 58/139 (41%), Gaps = 31/139 (22%)
Query: 338 QQHYAPPPPPPPPISHPMPHPPQAAGTPHLVYSQAPPPPMTSAPPPITPPPGHIIAQMPP 397
+Q PPPPPP + +P PP G PP P+ APPP TP
Sbjct: 309 RQEPLPPPPPPSRGGNQLPRPPIVGGNKGRS-GPLPPVPLGIAPPPPTPR---------- 357
Query: 398 YMNHPPPGPPPPQHGGPPVTAPPPHHYNPNSLPQFTEDQGTLSPPFTQPGGMSPGIWPAP 457
GPPPP GGPP PPP P T G L PP PG P + P P
Sbjct: 358 -------GPPPPGRGGPP---PPP--------PPATGRSGPLPPP--PPGAGGPPMPPPP 397
Query: 458 RGPPPPPRLQGPPSQTPLP 476
PPPPP P+ PLP
Sbjct: 398 PPPPPPPSSGNGPAPPPLP 416
Score = 70.5 bits (171), Expect = 3e-12
Identities = 51/151 (33%), Positives = 59/151 (39%), Gaps = 36/151 (23%)
Query: 306 REPPPPAPAPAHHHPEYQGQPVVS----HPHHIMPPQQHYAPPPPPPPPISHPMPHPPQA 361
+EP PP P P+ + P+V + P APPPP P P PP
Sbjct: 310 QEPLPPPPPPSRGGNQLPRPPIVGGNKGRSGPLPPVPLGIAPPPPTPRG-----PPPPGR 364
Query: 362 AGTPHLVYSQAPPPPMTSAPPPITPPPGHIIAQMPPYMNHPPPGPPPPQHGGPPVTAPPP 421
G P PPPP T P+ PPP A PP PPP PPPP G P APPP
Sbjct: 365 GGPP------PPPPPATGRSGPLPPPPPG--AGGPPMPPPPPPPPPPPSSGNGP--APPP 414
Query: 422 HHYNPNSLPQFTEDQGTLSPPFTQPGGMSPG 452
L P GG++PG
Sbjct: 415 -----------------LPPALVPAGGLAPG 428
Score = 47.8 bits (112), Expect = 2e-05
Identities = 45/173 (26%), Positives = 55/173 (31%), Gaps = 61/173 (35%)
Query: 192 RAGKPVTRASLENVHPPIAPPP-----TEIPERFIMPPDKHHMSHIPPKQHIMMPPPPLQ 246
+ G R + P PPP ++P I+ +K +PP + PPPP
Sbjct: 297 QGGLEAVRQEMRRQEPLPPPPPPSRGGNQLPRPPIVGGNKGRSGPLPPVPLGIAPPPPTP 356
Query: 247 HVPHEHYNQPHEDIRAPPAELSMAPPPPRSVSQETFRISTRKHSNLITVPIQDDSNSGAR 306
P PP PPPP + + SG
Sbjct: 357 RGP------------PPPGRGGPPPPPPPATGR-----------------------SGPL 381
Query: 307 EPPPPAPAPAHHHPEYQGQPVVSHPHHIMPPQQHYAPPPPPPPPISHPMPHPP 359
PPPP G P MPP PPPPPPPP S P PP
Sbjct: 382 PPPPPGAG---------GPP--------MPP----PPPPPPPPPSSGNGPAPP 413
Score = 45.8 bits (107), Expect = 9e-05
Identities = 30/80 (37%), Positives = 34/80 (42%), Gaps = 11/80 (13%)
Query: 402 PPPGPPPPQHGGPPVTAPPPHHYNPNSLPQFTEDQGTLSPPFTQPGGMSPGIWPAPRGPP 461
P P PPPP GG + PP N +G P P G++P P PRGPP
Sbjct: 312 PLPPPPPPSRGGNQLPRPPIVGGN----------KGRSGPLPPVPLGIAPPP-PTPRGPP 360
Query: 462 PPPRLQGPPSQTPLPGPHHP 481
PP R PP P G P
Sbjct: 361 PPGRGGPPPPPPPATGRSGP 380
>gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo
sapiens]
Length = 505
Score = 79.7 bits (195), Expect = 5e-15
Identities = 52/134 (38%), Positives = 58/134 (43%), Gaps = 26/134 (19%)
Query: 336 PPQQHYAPPPPPPPPISHPMPHPPQAAGTPHLVYSQAPPPPM---TSAPPPITPPPGHII 392
PP + PPPPPPP S P P P + G P PPPP T+APPP PP +
Sbjct: 281 PPSRGGPPPPPPPPHNSGPPPPPARGRGAP-------PPPPSRAPTAAPPP-PPPSRPSV 332
Query: 393 AQMPPYMNHPPPGPPPPQHGGPPVTAPPPHHYNPNSLPQFTEDQGTLSPPFTQPGGMSPG 452
A PP N P PPP P PPP P G ++PP P
Sbjct: 333 AVPPPPPNRMYPPPPPALPSSAPSGPPPP--------PPSVLGVGPVAPPPPPPP----- 379
Query: 453 IWPAPRGPPPPPRL 466
P P GPPPPP L
Sbjct: 380 --PPPPGPPPPPGL 391
Score = 70.1 bits (170), Expect = 4e-12
Identities = 46/121 (38%), Positives = 56/121 (46%), Gaps = 18/121 (14%)
Query: 305 AREPPPPAPAPAHHH----PEYQGQPVVSHPHHIMPPQQHYAPPPPPPPPISHPMPHPPQ 360
+R PPP P P H+ P +G+ P P APPPPPP S +P PP
Sbjct: 283 SRGGPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTA---APPPPPPSRPSVAVPPPP- 338
Query: 361 AAGTPHLVYSQAPPPPMTSAPPPITPPPGHIIAQMPPYMNHPPPGPPPPQHGGPPVTAPP 420
P+ +Y PP +SAP PPP ++ P PPP PPPP GPP PP
Sbjct: 339 ----PNRMYPPPPPALPSSAPSGPPPPPPSVLGVGPVAPPPPPPPPPPP---GPP---PP 388
Query: 421 P 421
P
Sbjct: 389 P 389
Score = 58.9 bits (141), Expect = 1e-08
Identities = 48/152 (31%), Positives = 55/152 (36%), Gaps = 43/152 (28%)
Query: 241 PPPPLQHVPHEHYNQPHED-IRAPPAELSMAPPPPRSVSQETFRISTRKHSNLITVPIQD 299
PPPP + P PH PPA APPPP
Sbjct: 279 PPPPSRGGPPPPPPPPHNSGPPPPPARGRGAPPPP------------------------- 313
Query: 300 DSNSGAREPPPPAPAPAHHHPEYQGQPVVSHPHHIMPPQQHYAPPPP--PPPPISHPMPH 357
S + PPPP P+ +P V+ P PP + Y PPPP P S P P
Sbjct: 314 PSRAPTAAPPPPPPS----------RPSVAVPPP--PPNRMYPPPPPALPSSAPSGPPPP 361
Query: 358 PPQAAGTPHLVYSQAPPPPMTSAPPPITPPPG 389
PP G + PPPP PP PPPG
Sbjct: 362 PPSVLGVGPVAPPPPPPPPPPPGPP---PPPG 390
Score = 51.2 bits (121), Expect = 2e-06
Identities = 49/166 (29%), Positives = 59/166 (35%), Gaps = 41/166 (24%)
Query: 210 APPPTEIPERFIMPPDKHHMSHIPPKQHIMMPPPPLQHVPHEHYNQPHEDIRAPPAELSM 269
APPP P R PP PP H PPPP P APP S
Sbjct: 276 APPPPP-PSRGGPPPP-------PPPPHNSGPPPP-----------PARGRGAPPPPPSR 316
Query: 270 AP---PPPRSVSQETFRISTRKHSNLITVPIQDDSNSGAREPPPPAPAPAHHHPEYQGQP 326
AP PPP S+ + + + + P +S PPPP P+ P
Sbjct: 317 APTAAPPPPPPSRPSVAVPPPPPNRMYPPPPPALPSSAPSGPPPPPPSVLGVGP------ 370
Query: 327 VVSHPHHIMPPQQHYAPPPPPPPPISHPMPHPPQAAGTPHLVYSQA 372
+ PP PPPPPPP P P P + H V + A
Sbjct: 371 -------VAPP------PPPPPPPPPGPPPPPGLPSDGDHQVPTTA 403
>gi|91199543 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo
sapiens]
Length = 1858
Score = 79.7 bits (195), Expect = 5e-15
Identities = 69/230 (30%), Positives = 87/230 (37%), Gaps = 55/230 (23%)
Query: 308 PPPPAPAPAHH-------HPEYQGQPVVSHPHHIMPPQQ--------HYAPPPPPPPPI- 351
PPPP PAP H H ++ VV H + P H PPPPPP P
Sbjct: 1629 PPPPPPAPGPHLVQQPNSHQQHSVAHVVGPVHAVTPGSHIHSQTAGHHLPPPPPPPGPAP 1688
Query: 352 -SHPMPHPPQA-----AGTPHLVYSQAPPPPMTSAPPPITPPPGHIIAQ-----MPPYMN 400
HP PHP A H+V S PPPP PPP ++A ++
Sbjct: 1689 HHHPPPHPSTGLQGLQAQHQHVVNSAPPPPP--------PPPPSSVLASGHHTTSAQALH 1740
Query: 401 HPP-PGPPPPQHGGPPVTAPPP----HHYNPNSLPQFTEDQGT-------LSPPFTQPGG 448
HPP GPP P P P HH PQ + GT ++ P QP G
Sbjct: 1741 HPPHQGPPLFPSSAHPTVPPYPSQATHHTTLGPGPQH-QPSGTGPHCPLPVTGPHLQPQG 1799
Query: 449 -------MSPGIWPAPRGPPPPPRLQGPPSQTPLPGPHHPDQTRYRPYYQ 491
+ G P P P +QGP +P+PG + + P +Q
Sbjct: 1800 PNSIPTPTASGFCPHPGSVALPHGVQGPQQASPVPGQIPIHRAQVPPTFQ 1849
Score = 77.8 bits (190), Expect = 2e-14
Identities = 95/403 (23%), Positives = 132/403 (32%), Gaps = 101/403 (25%)
Query: 174 RTYLSQRDLQAHINHRHMRAGKPVT--RASLENVHPPIAPPPTEI---PERFIMPPDKHH 228
+T L Q+ L + N + P T R S E + + PT++ P + P K
Sbjct: 1396 KTELQQKQLSNN-NQALSKNHPPQTHVRNSSEQLSQKLPSVPTKLHCPPSPHLENPPKSS 1454
Query: 229 MSHIPPKQHIMMPPPPLQHV--PHEHYNQPHEDIRAP---------PAELSMAPPPPRSV 277
H P + + P PP Q + P+ ++ + P PA ++ ++
Sbjct: 1455 TPHTPVQHGYLSPKPPSQQLGSPYRPHHSQSPQVGTPQREPQRNFYPAAQNLPANTQQAT 1514
Query: 278 SQETFRISTRKHSNLITVPIQDDSNSGAREPPPPAPAPAHHHPEYQ-------------- 323
S F + S+ S + PPPP P P+ + + Q
Sbjct: 1515 SGTLFTQTPSGQSSATYSQFNQQSLNSTAPPPPPPPPPSSSYYQNQQPSANFQNYNQLKG 1574
Query: 324 ---------------------GQPVVSH---PHHIMPPQQ---HY------APPPPPPPP 350
Q V H P H +P Q H+ PPPPPPPP
Sbjct: 1575 SLSQQTVFTSGPNQALPGTTSQQTVPGHHVTPGHFLPSQNPTIHHQTAAAVVPPPPPPPP 1634
Query: 351 ISHP----MPHPPQAAGTPHLV------------YSQA-----PPPPMTSAPPPITPPPG 389
P P+ Q H+V +SQ PPPP P P PP
Sbjct: 1635 APGPHLVQQPNSHQQHSVAHVVGPVHAVTPGSHIHSQTAGHHLPPPPPPPGPAPHHHPPP 1694
Query: 390 H-------IIAQMPPYMNHPPPGPPPP------QHGGPPVTAPPPHHYNPNSLPQFTEDQ 436
H + AQ +N PP PPPP G +A HH P F
Sbjct: 1695 HPSTGLQGLQAQHQHVVNSAPPPPPPPPPSSVLASGHHTTSAQALHHPPHQGPPLFPSSA 1754
Query: 437 GTLSPPFTQPGGMSPGIWPAPRGPPPPPRLQGPPSQTPLPGPH 479
PP+ + P GP P GP P+ GPH
Sbjct: 1755 HPTVPPYPSQATHHTTLGP---GPQHQPSGTGPHCPLPVTGPH 1794
>gi|33636768 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo
sapiens]
Length = 1858
Score = 79.7 bits (195), Expect = 5e-15
Identities = 69/230 (30%), Positives = 87/230 (37%), Gaps = 55/230 (23%)
Query: 308 PPPPAPAPAHH-------HPEYQGQPVVSHPHHIMPPQQ--------HYAPPPPPPPPI- 351
PPPP PAP H H ++ VV H + P H PPPPPP P
Sbjct: 1629 PPPPPPAPGPHLVQQPNSHQQHSVAHVVGPVHAVTPGSHIHSQTAGHHLPPPPPPPGPAP 1688
Query: 352 -SHPMPHPPQA-----AGTPHLVYSQAPPPPMTSAPPPITPPPGHIIAQ-----MPPYMN 400
HP PHP A H+V S PPPP PPP ++A ++
Sbjct: 1689 HHHPPPHPSTGLQGLQAQHQHVVNSAPPPPP--------PPPPSSVLASGHHTTSAQALH 1740
Query: 401 HPP-PGPPPPQHGGPPVTAPPP----HHYNPNSLPQFTEDQGT-------LSPPFTQPGG 448
HPP GPP P P P HH PQ + GT ++ P QP G
Sbjct: 1741 HPPHQGPPLFPSSAHPTVPPYPSQATHHTTLGPGPQH-QPSGTGPHCPLPVTGPHLQPQG 1799
Query: 449 -------MSPGIWPAPRGPPPPPRLQGPPSQTPLPGPHHPDQTRYRPYYQ 491
+ G P P P +QGP +P+PG + + P +Q
Sbjct: 1800 PNSIPTPTASGFCPHPGSVALPHGVQGPQQASPVPGQIPIHRAQVPPTFQ 1849
Score = 77.8 bits (190), Expect = 2e-14
Identities = 95/403 (23%), Positives = 132/403 (32%), Gaps = 101/403 (25%)
Query: 174 RTYLSQRDLQAHINHRHMRAGKPVT--RASLENVHPPIAPPPTEI---PERFIMPPDKHH 228
+T L Q+ L + N + P T R S E + + PT++ P + P K
Sbjct: 1396 KTELQQKQLSNN-NQALSKNHPPQTHVRNSSEQLSQKLPSVPTKLHCPPSPHLENPPKSS 1454
Query: 229 MSHIPPKQHIMMPPPPLQHV--PHEHYNQPHEDIRAP---------PAELSMAPPPPRSV 277
H P + + P PP Q + P+ ++ + P PA ++ ++
Sbjct: 1455 TPHTPVQHGYLSPKPPSQQLGSPYRPHHSQSPQVGTPQREPQRNFYPAAQNLPANTQQAT 1514
Query: 278 SQETFRISTRKHSNLITVPIQDDSNSGAREPPPPAPAPAHHHPEYQ-------------- 323
S F + S+ S + PPPP P P+ + + Q
Sbjct: 1515 SGTLFTQTPSGQSSATYSQFNQQSLNSTAPPPPPPPPPSSSYYQNQQPSANFQNYNQLKG 1574
Query: 324 ---------------------GQPVVSH---PHHIMPPQQ---HY------APPPPPPPP 350
Q V H P H +P Q H+ PPPPPPPP
Sbjct: 1575 SLSQQTVFTSGPNQALPGTTSQQTVPGHHVTPGHFLPSQNPTIHHQTAAAVVPPPPPPPP 1634
Query: 351 ISHP----MPHPPQAAGTPHLV------------YSQA-----PPPPMTSAPPPITPPPG 389
P P+ Q H+V +SQ PPPP P P PP
Sbjct: 1635 APGPHLVQQPNSHQQHSVAHVVGPVHAVTPGSHIHSQTAGHHLPPPPPPPGPAPHHHPPP 1694
Query: 390 H-------IIAQMPPYMNHPPPGPPPP------QHGGPPVTAPPPHHYNPNSLPQFTEDQ 436
H + AQ +N PP PPPP G +A HH P F
Sbjct: 1695 HPSTGLQGLQAQHQHVVNSAPPPPPPPPPSSVLASGHHTTSAQALHHPPHQGPPLFPSSA 1754
Query: 437 GTLSPPFTQPGGMSPGIWPAPRGPPPPPRLQGPPSQTPLPGPH 479
PP+ + P GP P GP P+ GPH
Sbjct: 1755 HPTVPPYPSQATHHTTLGP---GPQHQPSGTGPHCPLPVTGPH 1794
>gi|55750053 atrophin-1 [Homo sapiens]
Length = 1190
Score = 79.3 bits (194), Expect = 7e-15
Identities = 83/317 (26%), Positives = 109/317 (34%), Gaps = 58/317 (18%)
Query: 206 HPPIAPPPTEI-----PERFIMP--PDKHHMSHIPPKQHIMMPPPPLQHVPHEHYNQPHE 258
+P PPPT + P ++ P P + S PP PPPP + + H
Sbjct: 408 YPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPP------PPPPYGRLLAN--SNAHP 459
Query: 259 DIRAPPAELSMAPPPPRSVSQETFRISTRKHSNLITVPIQDDSNSGAREPPPPAPAP--- 315
P PP S + ++ Q + G PPPP P
Sbjct: 460 GPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPL 519
Query: 316 ----AHHHPEYQGQPVVSH-------PHHIMPP--QQHYAPPPPPPPPIS---------- 352
+HH Y P + P H+ PP Q Y+ P PP+S
Sbjct: 520 EGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTS 579
Query: 353 ---HPMPHPPQAAGTPHLVYSQAPPPPMTSAPPPITPPPGHIIAQMPPYMNHPPPGPPP- 408
+P HP + G Y P P +T++ ++ + + Y PPGPPP
Sbjct: 580 QGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPY 639
Query: 409 ----PQHGGPPVTAPPPHHYNPNSLPQFTED-----QGTLSPPFTQPGGMSPGIWPAPRG 459
P G PP Y P S P F +GT SPP PG PG G
Sbjct: 640 GKRAPSPGAYKTATPP--GYKPGSPPSFRTGTPPGYRGT-SPP-AGPGTFKPGSPTVGPG 695
Query: 460 PPPPPRLQGPPSQTPLP 476
P PP G PS P P
Sbjct: 696 PLPPAGPSGLPSLPPPP 712
Score = 64.7 bits (156), Expect = 2e-10
Identities = 74/295 (25%), Positives = 103/295 (34%), Gaps = 51/295 (17%)
Query: 208 PIAPPPTEIPERFIMPPDKHHMSHIPPKQHIMMPPPPLQ------HVPHEH-YNQPHEDI 260
P APPP P + P+ + P + PP L H+P H Q +
Sbjct: 286 PSAPPPANFPH---VTPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGL 342
Query: 261 RAPPAELSMAPPPPRSVSQETFRISTRKHSNLITVPIQDDSNSGAREPPPPAPAPAHHHP 320
P + P P S+ S+ + + P S+S A + + + P
Sbjct: 343 PPGPEKGPTLAPSPHSLPPA----SSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASP 398
Query: 321 EYQGQPVVSHPHHIMPPQQHYAPPPPPPPPISHPMPHPPQAAGTPHLVYSQAPPPPMTSA 380
Q + S+PH PPP +S+ P Q + V+SQ PPPP
Sbjct: 399 FPASQALPSYPHSF---------PPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPP---- 445
Query: 381 PPPITPPPGHIIAQMPPYMNHPPPGPPPPQHGGPPVTAPP--PHHYNPNSLPQFTEDQGT 438
PP G ++A ++ PGP PP G PP HH++ Q + Q
Sbjct: 446 -----PPYGRLLAN-----SNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQ 495
Query: 439 LSPPFTQPGGMSPGIWPAPRGPPPPPR----LQGPPSQTPLPGPHHPDQTRYRPY 489
Q G S GPPPP L+G S P P RPY
Sbjct: 496 QQQQQQQHHGNS--------GPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLRPY 542
Score = 58.9 bits (141), Expect = 1e-08
Identities = 68/237 (28%), Positives = 83/237 (35%), Gaps = 55/237 (23%)
Query: 274 PRSVSQETFRISTRKHSNLITVPIQDDSNSGAREPP----------PPAPAPAHHHPEYQ 323
PR + Q+ S +S +V DS+SG + P PP+P P P
Sbjct: 121 PRDIDQDNRSTSPSIYSPG-SVENDSDSSSGLSQGPARPYHPPPLFPPSPQPPDSTPR-- 177
Query: 324 GQPVVS-HPHHIMPPQQHYAPPPPPPP-----PISHPMPHPPQAAGTPHLVYSQAPPPPM 377
QP S PH + P ++AP PP P P PHP G V S P P
Sbjct: 178 -QPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPK 236
Query: 378 TSA--------------PPPITPPPGHIIAQMPPYMNHPPPGPP-PPQHGGPPVTAPPPH 422
PPP TP I PP PP P GG +APPP
Sbjct: 237 GGGAASSVGGPNGGKQHPPPTTP----ISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPA 292
Query: 423 HYNPNSLPQFTEDQGTLSPPFTQPGGMSPGIWPAPRGPPPPPRLQGPPSQTPLPGPH 479
++ P+ P L PP P + P PP L P LP PH
Sbjct: 293 NF-PHVTP-------NLPPP--------PALRPLNNASASPPGLGAQPLPGHLPSPH 333
Score = 58.5 bits (140), Expect = 1e-08
Identities = 90/355 (25%), Positives = 119/355 (33%), Gaps = 101/355 (28%)
Query: 207 PPIAPPPTEIPERFIMPPD---KHHMSHIPPKQHIMMPPPPLQHVPHEHYNQPHEDIRAP 263
PP+ PP + P+ P+ + H S P H M PP + +AP
Sbjct: 162 PPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRM------------FQAP 209
Query: 264 PAELSMAPPP-PRSVSQETFRISTRKHSNLITVPIQDDSNSGAREPPPPAPAPAHHHPEY 322
P APPP P+ T +++ P GA H P
Sbjct: 210 PG----APPPHPQLYPGGT--------GGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPT 257
Query: 323 QGQPVVSHPHHIMPPQQHYAPPPPPPPPISHPMPHPPQAAGTPHLVYSQAPPPPM----- 377
V S PP + PP P +P P A PH+ + PPP +
Sbjct: 258 TPISVSSSGASGAPPTK-----PPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNN 312
Query: 378 TSAPPP---ITPPPGHIIA--QMPPYMNHPPPGP------PPPQHGGPPVT----APP-- 420
SA PP P PGH+ + M M PPGP P H PP + APP
Sbjct: 313 ASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMR 372
Query: 421 -PHHYN------------------------------PNSLPQFTEDQGTLSPP-FTQPGG 448
P+ + P+S P T + PP +TQP
Sbjct: 373 FPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSL 432
Query: 449 MSPGIWPAPRGPPPPP---RLQGPPSQTPLPGP---------HHPDQTRYRPYYQ 491
S +W +GPPPPP RL + P P P H P T + + Q
Sbjct: 433 PSQAVW--SQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQ 485
Score = 30.0 bits (66), Expect = 5.0
Identities = 20/71 (28%), Positives = 28/71 (39%), Gaps = 2/71 (2%)
Query: 371 QAPPPPMTSAPPPITPP--PGHIIAQMPPYMNHPPPGPPPPQHGGPPVTAPPPHHYNPNS 428
+AP + P P PP PG +A +PPY+ P P P + +P
Sbjct: 846 RAPVECPSLGPVPHRPPFEPGSAVATVPPYLGPDTPALRTLSEYARPHVMSPGNRNHPFY 905
Query: 429 LPQFTEDQGTL 439
+P D G L
Sbjct: 906 VPLGAVDPGLL 916
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.139 0.466
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 35,656,865
Number of Sequences: 37866
Number of extensions: 3121219
Number of successful extensions: 73157
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 904
Number of HSP's successfully gapped in prelim test: 1782
Number of HSP's that attempted gapping in prelim test: 17921
Number of HSP's gapped (non-prelim): 21754
length of query: 491
length of database: 18,247,518
effective HSP length: 106
effective length of query: 385
effective length of database: 14,233,722
effective search space: 5479982970
effective search space used: 5479982970
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.