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Search of human proteins with 208431781
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|208431781 cyclic nucleotide gated channel beta 1 isoform b
[Homo sapiens]
(299 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|208431781 cyclic nucleotide gated channel beta 1 isoform b [H... 611 e-175
gi|114205399 cyclic nucleotide gated channel beta 1 isoform a [H... 597 e-171
gi|110349719 titin isoform N2-A [Homo sapiens] 55 1e-07
gi|55741677 SET domain containing 1A [Homo sapiens] 55 1e-07
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 51 1e-06
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 51 1e-06
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 51 1e-06
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 51 1e-06
gi|149773456 hypothetical protein LOC643314 [Homo sapiens] 50 2e-06
gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo sap... 49 7e-06
gi|117938768 GNAS complex locus alex [Homo sapiens] 48 9e-06
gi|210032580 SET domain containing 1B [Homo sapiens] 47 2e-05
gi|33356148 formin-like 1 [Homo sapiens] 46 5e-05
gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo sap... 45 6e-05
gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens] 45 6e-05
gi|157738619 smoothelin-like 1 [Homo sapiens] 45 6e-05
gi|116517292 cut-like 2 [Homo sapiens] 45 8e-05
gi|58761548 tau tubulin kinase 1 [Homo sapiens] 45 8e-05
gi|116256464 hypothetical protein LOC343990 [Homo sapiens] 45 8e-05
gi|14589876 embryonal Fyn-associated substrate isoform 2 [Homo s... 45 8e-05
gi|5031681 embryonal Fyn-associated substrate isoform 1 [Homo sa... 45 8e-05
gi|157168329 formin 1 [Homo sapiens] 45 1e-04
gi|30089948 protein phosphatase 1E [Homo sapiens] 45 1e-04
gi|31324577 molecule interacting with Rab13 [Homo sapiens] 45 1e-04
gi|145386517 phostensin [Homo sapiens] 44 2e-04
gi|199559805 phostensin [Homo sapiens] 44 2e-04
gi|153792074 proline rich 12 [Homo sapiens] 43 3e-04
gi|150170670 piccolo isoform 2 [Homo sapiens] 43 4e-04
gi|150378539 piccolo isoform 1 [Homo sapiens] 43 4e-04
gi|23957680 ral guanine nucleotide dissociation stimulator-like ... 42 5e-04
>gi|208431781 cyclic nucleotide gated channel beta 1 isoform b [Homo
sapiens]
Length = 299
Score = 611 bits (1575), Expect = e-175
Identities = 299/299 (100%), Positives = 299/299 (100%)
Query: 1 MLGWVQRVLPQPPGTPRKTKMQEEEEVEPEPEMEAEVEPEPNPEEAETESESMPPEESFK 60
MLGWVQRVLPQPPGTPRKTKMQEEEEVEPEPEMEAEVEPEPNPEEAETESESMPPEESFK
Sbjct: 1 MLGWVQRVLPQPPGTPRKTKMQEEEEVEPEPEMEAEVEPEPNPEEAETESESMPPEESFK 60
Query: 61 EEEVAVADPSPQETKEAALTSTISLRAQGAEISEMNSPSRRVLTWLMKGVEKVIPQPVHS 120
EEEVAVADPSPQETKEAALTSTISLRAQGAEISEMNSPSRRVLTWLMKGVEKVIPQPVHS
Sbjct: 61 EEEVAVADPSPQETKEAALTSTISLRAQGAEISEMNSPSRRVLTWLMKGVEKVIPQPVHS 120
Query: 121 ITEDPAQILGHGSTGDTGCTDEPNEALEAQDTRPGLRLLLWLEQNLERVLPQPPKSSEVW 180
ITEDPAQILGHGSTGDTGCTDEPNEALEAQDTRPGLRLLLWLEQNLERVLPQPPKSSEVW
Sbjct: 121 ITEDPAQILGHGSTGDTGCTDEPNEALEAQDTRPGLRLLLWLEQNLERVLPQPPKSSEVW 180
Query: 181 RDEPAVATGAASDPAPPGRPQEMGPKLQARETPSLPTPIPLQPKEEPKEAPAPEPQPGSQ 240
RDEPAVATGAASDPAPPGRPQEMGPKLQARETPSLPTPIPLQPKEEPKEAPAPEPQPGSQ
Sbjct: 181 RDEPAVATGAASDPAPPGRPQEMGPKLQARETPSLPTPIPLQPKEEPKEAPAPEPQPGSQ 240
Query: 241 AQTSSLPPTRDPARLVAWVLHRLEMALPQPVLHGKIGEQEPDSPGICDVQTRVMGAGGL 299
AQTSSLPPTRDPARLVAWVLHRLEMALPQPVLHGKIGEQEPDSPGICDVQTRVMGAGGL
Sbjct: 241 AQTSSLPPTRDPARLVAWVLHRLEMALPQPVLHGKIGEQEPDSPGICDVQTRVMGAGGL 299
>gi|114205399 cyclic nucleotide gated channel beta 1 isoform a [Homo
sapiens]
Length = 1251
Score = 597 bits (1538), Expect = e-171
Identities = 293/298 (98%), Positives = 294/298 (98%)
Query: 1 MLGWVQRVLPQPPGTPRKTKMQEEEEVEPEPEMEAEVEPEPNPEEAETESESMPPEESFK 60
MLGWVQRVLPQPPGTPRKTKMQEEEEVEPEPEMEAEVEPEPNPEEAETESESMPPEESFK
Sbjct: 1 MLGWVQRVLPQPPGTPRKTKMQEEEEVEPEPEMEAEVEPEPNPEEAETESESMPPEESFK 60
Query: 61 EEEVAVADPSPQETKEAALTSTISLRAQGAEISEMNSPSRRVLTWLMKGVEKVIPQPVHS 120
EEEVAVADPSPQETKEAALTSTISLRAQGAEISEMNSPSRRVLTWLMKGVEKVIPQPVHS
Sbjct: 61 EEEVAVADPSPQETKEAALTSTISLRAQGAEISEMNSPSRRVLTWLMKGVEKVIPQPVHS 120
Query: 121 ITEDPAQILGHGSTGDTGCTDEPNEALEAQDTRPGLRLLLWLEQNLERVLPQPPKSSEVW 180
ITEDPAQILGHGSTGDTGCTDEPNEALEAQDTRPGLRLLLWLEQNLERVLPQPPKSSEVW
Sbjct: 121 ITEDPAQILGHGSTGDTGCTDEPNEALEAQDTRPGLRLLLWLEQNLERVLPQPPKSSEVW 180
Query: 181 RDEPAVATGAASDPAPPGRPQEMGPKLQARETPSLPTPIPLQPKEEPKEAPAPEPQPGSQ 240
RDEPAVATGAASDPAPPGRPQEMGPKLQARETPSLPTPIPLQPKEEPKEAPAPEPQPGSQ
Sbjct: 181 RDEPAVATGAASDPAPPGRPQEMGPKLQARETPSLPTPIPLQPKEEPKEAPAPEPQPGSQ 240
Query: 241 AQTSSLPPTRDPARLVAWVLHRLEMALPQPVLHGKIGEQEPDSPGICDVQTRVMGAGG 298
AQTSSLPPTRDPARLVAWVLHRLEMALPQPVLHGKIGEQEPDSPGICDVQT + GG
Sbjct: 241 AQTSSLPPTRDPARLVAWVLHRLEMALPQPVLHGKIGEQEPDSPGICDVQTISILPGG 298
Score = 35.4 bits (80), Expect = 0.061
Identities = 54/235 (22%), Positives = 80/235 (34%), Gaps = 21/235 (8%)
Query: 6 QRVLPQPPGTPRKTKMQEEEE-VEPEPEMEAEVEPEPNPEEAETESESMPPEESFKE--- 61
Q V P GT +EE + VE P + +E E EE E E E EE E
Sbjct: 318 QDVSTSPQGTEVVPAYEEENKAVEKMPRELSRIEEEKEDEEEEEEEEEEEEEEEVTEVLL 377
Query: 62 -----EEVAVADPS-----PQETKEAALTSTISLRAQGAEISEMNSPSRRVLTWLMKGVE 111
+V V PQ T + L + A+ E ++ + +
Sbjct: 378 DSCVVSQVGVGQSEEDGTRPQSTSDQKLWEEVGEEAK----KEAEEKAKEEAEEVAEEEA 433
Query: 112 KVIPQPVHSITEDPAQILGHGSTGDTGCTDEPNEALEAQDTRPGLRLLLWLEQNLERVLP 171
+ PQ E+P S+G P ++ +DT L+ E VLP
Sbjct: 434 EKEPQDWAETKEEPEAEAEAASSGVPATKQHPE--VQVEDTDADSCPLMAEENPPSTVLP 491
Query: 172 QPPKSSEVWRDEPAVATGAASDPAPPGRPQ-EMGPKLQARETPSLPTPIPLQPKE 225
P + P+ A+G P + E L E+P + P PK+
Sbjct: 492 PPSPAKSDTLIVPSSASGTHRKKLPSEDDEAEELKALSPAESPVVAWSDPTTPKD 546
Score = 33.1 bits (74), Expect = 0.31
Identities = 53/234 (22%), Positives = 89/234 (38%), Gaps = 25/234 (10%)
Query: 16 PRKTKMQEE-EEVEPEPEMEAEVEPEPNPEEAETESESMPPEESFKEEEVAVADPSPQET 74
P+ T Q+ EEV E + EAE E+A+ E+E + EE+ KE + E
Sbjct: 397 PQSTSDQKLWEEVGEEAKKEAE-------EKAKEEAEEVAEEEAEKEPQDWAETKEEPEA 449
Query: 75 KEAALTSTISLRAQGAEISEMNSPSRRVLTWLMKGVEKVIPQPVHSITEDPAQILGHGS- 133
+ A +S + Q E+ ++ + + + P D + S
Sbjct: 450 EAEAASSGVPATKQHPEVQVEDTDADSCPLMAEENPPSTVLPPPSPAKSDTLIVPSSASG 509
Query: 134 TGDTGCTDEPNEALEAQDTRPG-LRLLLWLEQNLERVLPQPPKSSEVWRDEPAVATGAAS 192
T E +EA E + P ++ W + P PK ++ + A +T + +
Sbjct: 510 THRKKLPSEDDEAEELKALSPAESPVVAWSD-------PTTPKDTD--GQDRAASTASTN 560
Query: 193 DPAPPGRPQEMGPKLQARE---TPSLPTPIPLQPKEEPKEAP---APEPQPGSQ 240
R QE+ + R L P +E PK +P APEP P ++
Sbjct: 561 SAIINDRLQELVKLFKERTEKVKEKLIDPDVTSDEESPKPSPAKKAPEPAPDTK 614
Score = 32.3 bits (72), Expect = 0.52
Identities = 28/104 (26%), Positives = 40/104 (38%), Gaps = 24/104 (23%)
Query: 167 ERVLPQPPKSSEVWRDEPAVATG-------AASDPAPPGRPQEMGPKLQARETPSLPTPI 219
+ ++ Q S +V +E + A AA+DP P P E PS P P
Sbjct: 1149 QELVEQAKSSQDVKGEEGSAAPDQHTHPKEAATDPPAPRTPPE-----PPGSPPSSPPPA 1203
Query: 220 PLQPKEEPKEAPA------------PEPQPGSQAQTSSLPPTRD 251
L E +E PA P P+PG Q + +P R+
Sbjct: 1204 SLGRPEGEEEGPAEPEEHSVRICMSPGPEPGEQILSVKMPEERE 1247
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 54.7 bits (130), Expect = 1e-07
Identities = 68/285 (23%), Positives = 116/285 (40%), Gaps = 53/285 (18%)
Query: 6 QRVLPQPPGTPRKTK-MQEEEEVEPEPE--MEAEVEPEPNPEEAETESESMPPEESFKEE 62
+ ++P+ P + + + EEEEV PE E + E E P EE E E +P EE F E
Sbjct: 10111 EEIVPEEEVLPEEEEVLPEEEEVLPEEEEVLPEEEEIPPEEEEVPPEEEYVPEEEEFVPE 10170
Query: 63 E---------VAVADPSPQETKEAALTSTISLRAQGAEISEMNSPSRRV--LTWLMKGVE 111
E V V P P+ K+ + + + A +++ ++V ++ E
Sbjct: 10171 EEVLPEVKPKVPVPAPVPEIKKKVTEKKVVIPKKEEAPPAKVPEVPKKVEEKRIILPKEE 10230
Query: 112 KVIPQPVHSITEDPAQILGHGSTGDTGCTDEPNEALEAQDTRPGLRLLLWLEQNLERVLP 171
+V+P +TE+P +EP E + P + + +E V
Sbjct: 10231 EVLPV---EVTEEP--------------EEEPISEEEIPEEPPSI-------EEVEEV-- 10264
Query: 172 QPPKSSEVWRDEPAVATGAASDPAPPGRPQEMGPKLQARETPSLPTPIPLQPKEEPKEAP 231
PP+ EV + P P + E P +++ P P+P+Q KE P P
Sbjct: 10265 APPRVPEV------IKKAVPEAPTPVPKKVEAPPAKVSKKIPEEKVPVPVQKKEAP---P 10315
Query: 232 APEPQ-PGSQAQTSSLPPTRD---PARLVAWVLHRLEMALPQPVL 272
A P+ P + L P ++ PA+ + ++ +A Q V+
Sbjct: 10316 AKVPEVPKKVPEKKVLVPKKEAVPPAKGRTVLEEKVSVAFRQEVV 10360
Score = 42.4 bits (98), Expect = 5e-04
Identities = 57/262 (21%), Positives = 92/262 (35%), Gaps = 48/262 (18%)
Query: 6 QRVLPQPPGTPRKTKMQEEEEVEPEPEMEAEVEPEPN----------------------- 42
QR PP P K + EE +P P E EV P P
Sbjct: 9390 QREESPPPAVPEIPKKKVPEERKPVPRKEEEVPPPPKVPALPKKPVPEEKVAVPVPVAKK 9449
Query: 43 --PEEAETESESMPPEESF-KEEEVAVADPSPQETKEAALTS----TISLRAQGAEISEM 95
P AE +++ E+ F EE+++ A P E +++ + S +G IS
Sbjct: 9450 APPPRAEVSKKTVVEEKRFVAEEKLSFAVPQRVEVTRHEVSAEEEWSYSEEEEGVSISVY 9509
Query: 96 NSPSRRVLTWLMKGVEKVIPQPVHSITEDPAQILGHGSTGDTGCTDEPNEALEAQDTRPG 155
R +V+ +P + E+ I+ EP E E Q+ +
Sbjct: 9510 REEEREEEEEAEVTEYEVMEEPEEYVVEEKLHIISKRVEA------EPAEVTERQEKK-- 9561
Query: 156 LRLLLWLEQNLERVLPQPPKSSEVWRDEPAVATGAASDPAPPGRPQEMGPKLQARETPSL 215
+ L+ + + +PP + + P PAP + +++ P + E P
Sbjct: 9562 ----IVLKPKIPAKIEEPPPAKV--PEAPKKIVPEKKVPAPVPKKEKVPPP-KVPEEPKK 9614
Query: 216 PTPIPLQPKEEPKEAPAPEPQP 237
P P + K PK EP P
Sbjct: 9615 PVP---EKKVPPKVIKMEEPLP 9633
Score = 41.6 bits (96), Expect = 9e-04
Identities = 62/268 (23%), Positives = 100/268 (37%), Gaps = 32/268 (11%)
Query: 13 PGTPRKTKMQEEEEVEPEPEMEAEVEPE--PNPEEAETESESMPPEES----FKEEEVAV 66
P P+K ++E+ V P PE PE PEE E E P EE +EEE V
Sbjct: 10776 PEVPKKPVLEEKPAV-PVPERAESPPPEVYEEPEEIAPEEEIAPEEEKPVPVAEEEEPEV 10834
Query: 67 ADPS-PQETKEAALTSTISLRAQGAEISEMNSPSRRVLTWLMKGVEKVIPQPVHSITEDP 125
P+ P+E K+ + + + E P + K + P P ED
Sbjct: 10835 PPPAVPEEPKKIIPEKKVPV-IKKPEAPPPKEPEPEKVIEKPKLKPRPPPPPPAPPKEDV 10893
Query: 126 AQILGHGSTGDTGCTDEPNEALEAQDTRPGLRLLLWLEQNLERVLPQ---PPKSSEVWR- 181
+ + E + E + P + E+ + ++LP+ PK V +
Sbjct: 10894 KEKIFQLKAIPKKKVPEKPQVPEKVELTP--LKVPGGEKKVRKLLPERKPEPKEEVVLKS 10951
Query: 182 --------DEPAVATG--------AASDPAPPGRPQEMGPKLQARETPSLPTPIPLQPKE 225
+EP V A +P PP +E+ + +P P + +
Sbjct: 10952 VLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEVEVPTVTKRERKIPEPTKVPEIK 11011
Query: 226 EPKEAPAPEPQPGSQAQTSSL-PPTRDP 252
PAPEP+P +A+ ++ PP +P
Sbjct: 11012 PAIPLPAPEPKPKPEAEVKTIKPPPVEP 11039
Score = 40.0 bits (92), Expect = 0.002
Identities = 60/257 (23%), Positives = 99/257 (38%), Gaps = 60/257 (23%)
Query: 6 QRVLPQPPGTPRKTKMQEEEEVEPE--PEMEAEVEPEPNPEEAETESESMPPEESFKE-E 62
++ +P PP P+K EV P PE+ PE EA PP E F+E E
Sbjct: 10619 EKKVPVPP--PKKP------EVPPTKVPEVPKVAVPEKKVPEAIPPKPESPPPEVFEEPE 10670
Query: 63 EVAVADPSPQ--ETKEAALTSTISLR--------------AQGAEISEMNSPSRRVLTWL 106
EVA+ +P + E E A +++ A+ E+ + P
Sbjct: 10671 EVALEEPPAEVVEEPEPAAPPQVTVPPKKPVPEKKAPAVVAKKPELPPVKVPEVPKEVVP 10730
Query: 107 MKGVEKVIPQ----PVHSITEDPAQILGHGSTGDTGCTDEPNEALEAQDTRPGLRLLLWL 162
K V V+P+ P + E P +++ E A+ + P +
Sbjct: 10731 EKKVPLVVPKKPEAPPAKVPEVPKEVV-----------PEKKVAVPKKPEVPPAK----- 10774
Query: 163 EQNLERVLPQPPKSSEVWRDEPAVATGAASDPAPP---GRPQEMGPKLQARETPSLPTPI 219
+P+ PK V ++PAV ++ PP P+E+ P+ + P P+
Sbjct: 10775 -------VPEVPK-KPVLEEKPAVPVPERAESPPPEVYEEPEEIAPEEEI--APEEEKPV 10824
Query: 220 PLQPKEEPKEAPAPEPQ 236
P+ +EEP+ P P+
Sbjct: 10825 PVAEEEEPEVPPPAVPE 10841
Score = 39.7 bits (91), Expect = 0.003
Identities = 58/259 (22%), Positives = 96/259 (37%), Gaps = 38/259 (14%)
Query: 9 LPQPPGTPRKTKMQEEEEVEPEPEMEAEVEPEPNPEEAET-----ESESMPPEESFKEEE 63
+P+ P +K + ++VE P EV + PEE + + E+ PP+ K E
Sbjct: 10035 VPKKPVPEKKVPVPAPKKVEAPPAKVPEVPKKLIPEEKKPTPVPKKVEAPPPKVPKKREP 10094
Query: 64 VAVADPSPQETKEAALTSTISLRAQGAEISEMNSPSRRVLTWLMKGVEKVIPQPVHSITE 123
V V PQE + E P VL E+V+P+ + E
Sbjct: 10095 VPVPVALPQE--------------EEVLFEEEIVPEEEVL----PEEEEVLPEEEEVLPE 10136
Query: 124 DPAQILGHGSTGDTGCTDEPNEALEAQDTRPGLRLLLWLEQNLERVLPQPPKSSEVWRDE 183
+ + + E E ++ P + E+ L V P+ P + V +
Sbjct: 10137 EEEVL-----PEEEEIPPEEEEVPPEEEYVPEEEEFVPEEEVLPEVKPKVPVPAPVPEIK 10191
Query: 184 PAVATGAASDP----APPGRPQEMGPKLQARE--TPSLPTPIPLQPKEEPKEAPAPE--- 234
V P APP + E+ K++ + P +P++ EEP+E P E
Sbjct: 10192 KKVTEKKVVIPKKEEAPPAKVPEVPKKVEEKRIILPKEEEVLPVEVTEEPEEEPISEEEI 10251
Query: 235 -PQPGSQAQTSSLPPTRDP 252
+P S + + P R P
Sbjct: 10252 PEEPPSIEEVEEVAPPRVP 10270
Score = 38.9 bits (89), Expect = 0.006
Identities = 71/296 (23%), Positives = 109/296 (36%), Gaps = 52/296 (17%)
Query: 5 VQRVLPQPPGTPRKTKMQEEEEVEPEPEMEAEVEPEPNPEEAETESESMPPEESFKEEE- 63
V +P P +P +E EEV E E AEV EP P A ++PP++ E++
Sbjct: 10650 VPEAIPPKPESPPPEVFEEPEEVALE-EPPAEVVEEPEP--AAPPQVTVPPKKPVPEKKA 10706
Query: 64 --VAVADPS------PQETKEAALTSTISL------RAQGAEISEMNS---PSRRVLTWL 106
V P P+ KE + L A A++ E+ P ++V
Sbjct: 10707 PAVVAKKPELPPVKVPEVPKEVVPEKKVPLVVPKKPEAPPAKVPEVPKEVVPEKKVAVPK 10766
Query: 107 MKGVE--KVIPQPVHSITED-PA-QILGHGSTGDTGCTDEPNEALEAQDTRPGLRLLLWL 162
V KV P + E+ PA + + +EP E ++ P + +
Sbjct: 10767 KPEVPPAKVPEVPKKPVLEEKPAVPVPERAESPPPEVYEEPEEIAPEEEIAPEEEKPVPV 10826
Query: 163 EQNLERVLPQP-----PKSSEVWRDEPAVATGAASDPAPPGRPQEM--GPKLQARETPSL 215
+ E +P P PK + P + A P P P+++ PKL+ R P
Sbjct: 10827 AEEEEPEVPPPAVPEEPKKIIPEKKVPVIKKPEAPPPKEP-EPEKVIEKPKLKPRPPPPP 10885
Query: 216 PTPIPLQPKEE-------PKEAPAPEPQ------------PGSQAQTSSLPPTRDP 252
P P KE+ PK+ +PQ PG + + L P R P
Sbjct: 10886 PAPPKEDVKEKIFQLKAIPKKKVPEKPQVPEKVELTPLKVPGGEKKVRKLLPERKP 10941
Score = 35.8 bits (81), Expect = 0.047
Identities = 60/293 (20%), Positives = 111/293 (37%), Gaps = 56/293 (19%)
Query: 5 VQRVLPQPP--------GTPRKTKMQEEEEVEPEPEMEAEVEPEPNPEEAET-------- 48
+++ +P+ P P K + EE P P + E P PE +
Sbjct: 10273 IKKAVPEAPTPVPKKVEAPPAKVSKKIPEEKVPVPVQKKEAPPAKVPEVPKKVPEKKVLV 10332
Query: 49 -ESESMPPEE--SFKEEEVAVADPSPQETKEAALTSTISLRAQGAEISEMNSPSR--RVL 103
+ E++PP + + EE+V+VA +E + + L AE+ E+ V
Sbjct: 10333 PKKEAVPPAKGRTVLEEKVSVAF-----RQEVVVKERLELEVVEAEVEEIPEEEEFHEVE 10387
Query: 104 TWLMKG----VEKVIPQPVHSITEDPA-----QILGHGSTGDTGCTDEPNEALEAQDT-- 152
+ +G VE+ I H + E+ +++ + ++P + +
Sbjct: 10388 EYFEEGEFHEVEEFIKLEQHRVEEEHRVEKVHRVIEVFEAEEVEVFEKPKAPPKGPEISE 10447
Query: 153 ------RPGLRLLLWLEQNLERVLPQPPKSSEVWR-----DEPAVATGAASDPAPPGR-- 199
+P +++ E + +P+ PK V +EP V + PP
Sbjct: 10448 KIIPPKKPPTKVVPRKEPPAK--VPEVPKKIVVEEKVRVPEEPRVPPTKVPEVLPPKEVV 10505
Query: 200 PQEMGPKLQARETPSLPTPIPLQPKEEPKEAPAPEPQPGSQAQTSSLPPTRDP 252
P++ P A++ + P +P PKE E P P P + +PPT+ P
Sbjct: 10506 PEKKVPVPPAKKPEAPPPKVPEAPKEVVPEKKVPVPPP----KKPEVPPTKVP 10554
Score = 34.7 bits (78), Expect = 0.10
Identities = 64/287 (22%), Positives = 112/287 (39%), Gaps = 45/287 (15%)
Query: 16 PRKTKMQEEEEVE-PEPEMEAEVEPEPNPEEAETESESMP--PEESFKEEEVAVADPSPQ 72
P+K K + E P+ + E P P P++ E +P P++ E++V V P
Sbjct: 9994 PKKEKPPPAKVPEVPKKPVPEEKVPVPVPKKVEAPPAKVPEVPKKPVPEKKVPVPAPKKV 10053
Query: 73 ETKEAALTSTISLRAQGAEISEMNSPSRRVLTWLMKGVEKVIPQPVHSITEDPAQILGHG 132
E A + E+ + P + T + K VE P P +P +
Sbjct: 10054 EAPPAKV----------PEVPKKLIPEEKKPTPVPKKVE--APPPKVPKKREPVPVPVAL 10101
Query: 133 STGDTGCTDEPNEALEAQDTRPGLRLLLWLEQNL----ERVLPQ----PPKSSEVWRDEP 184
+ +E E + ++ P +L E+ + E VLP+ PP+ EV +E
Sbjct: 10102 PQEEEVLFEE--EIVPEEEVLPEEEEVLPEEEEVLPEEEEVLPEEEEIPPEEEEVPPEEE 10159
Query: 185 AVATGAASDPAPPGRPQEMGPKLQARETPSLPTPIP-LQPKEEPKEAPAPEPQPGSQAQT 243
V P P E+ PK+ +P P+P ++ K K+ P+ + A+
Sbjct: 10160 YVPEEEEFVPEEEVLP-EVKPKV------PVPAPVPEIKKKVTEKKVVIPKKEEAPPAKV 10212
Query: 244 SSLPPTRDPARLVAWVLHRLEMALP---------QPVLHGKIGEQEP 281
+P + R+ +L + E LP +P+ +I E+ P
Sbjct: 10213 PEVPKKVEEKRI---ILPKEEEVLPVEVTEEPEEEPISEEEIPEEPP 10256
Score = 34.7 bits (78), Expect = 0.10
Identities = 50/236 (21%), Positives = 89/236 (37%), Gaps = 57/236 (24%)
Query: 10 PQPPGTPRKTKMQEEEEVEPEPEMEAEVEPEPNPEEAETESESMPPEESFKEEEVAVADP 69
P PP P++ ++ +++ P+ + +P+ PE+ E +P E + + P
Sbjct: 10883 PPPPAPPKEDVKEKIFQLKAIPKKKVPEKPQV-PEKVELTPLKVPGGEKKVRKLLPERKP 10941
Query: 70 SPQETKEAALTSTISLRAQGAEISEMNSPSRRVLTWLMKGVEKVIPQPVHSITEDPAQIL 129
P+E E L S LR + E P + L K + +P+P
Sbjct: 10942 EPKE--EVVLKSV--LRKRPEEEEPKVEPKK-----LEKVKKPAVPEPP----------- 10981
Query: 130 GHGSTGDTGCTDEPNEALEAQDTRPGLRLLLWLEQNLERVLPQPPKSSEVWRDEPAVATG 189
+P E +E ER +P+P K E+ +PA+
Sbjct: 10982 ----------PPKPVEEVEVPTVT-----------KRERKIPEPTKVPEI---KPAIPL- 11016
Query: 190 AASDPAPPGRPQEMGPKLQARETPSLPTPIPLQPKEEPKEAPAPEPQPGSQAQTSS 245
PAP +P+ P+ + + P P++P+ P AP P G +A+ +
Sbjct: 11017 ----PAPEPKPK---PEAEVKTIK----PPPVEPEPTPIAAPVTVPVVGKKAEAKA 11061
Score = 34.7 bits (78), Expect = 0.10
Identities = 31/118 (26%), Positives = 47/118 (39%), Gaps = 9/118 (7%)
Query: 14 GTPRKTKMQEEEEVEPEPEMEAEVEPEPNPEEAE-------TESESMPPEESFKEEEVAV 66
G + K +EE +P+ ++ + P+P EAE + E P E F + AV
Sbjct: 11054 GKKAEAKAPKEEAAKPKGPIKGVPKKTPSPIEAERRKLRPGSGGEKPPDEAPFTYQLKAV 11113
Query: 67 ADPSPQETKEAALTSTISLRAQGAEISEMNSPSRRVLTWLMKGVEKVIPQPVHSITED 124
+E K+ LT + A + SPS + TW MK + P H D
Sbjct: 11114 PLKFVKEIKDIILTES-EFVGSSAIFECLVSPSTAITTW-MKDGSNIRESPKHRFIAD 11169
Score = 33.9 bits (76), Expect = 0.18
Identities = 60/269 (22%), Positives = 100/269 (37%), Gaps = 45/269 (16%)
Query: 13 PGTPRKTKMQEEEEVEPEPEMEAEVEPEPNPEEAETESESMPPEESFKEEEVAVADPSPQ 72
P P+K ++E+ V EP + PE P + + +P + K E A P+
Sbjct: 10470 PEVPKKIVVEEKVRVPEEPRVPPTKVPEVLPPKEVVPEKKVPVPPAKKPE--APPPKVPE 10527
Query: 73 ETKEAALTSTISL-RAQGAEISEMNSPSRRVLTWLMKGVEKVIP----QPVHSITEDPAQ 127
KE + + + E+ P K V + IP P + E P +
Sbjct: 10528 APKEVVPEKKVPVPPPKKPEVPPTKVPEVPKAAVPEKKVPEAIPPKPESPPPEVPEAPKE 10587
Query: 128 ILGHGSTGDTGCTDEPNEALEAQDTRPGLRLLLWLEQNLERVLPQ------PPKSSEV-- 179
++ P + + A + + + + + V+P+ PPK EV
Sbjct: 10588 VV-------------PEKKVPAAPPKKPEVTPVKVPEAPKEVVPEKKVPVPPPKKPEVPP 10634
Query: 180 --WRDEPAVATGAASDP-APPGRPQEMGPKL-QARETPSLPTPIPLQPKEEPKEA----- 230
+ P VA P A P +P+ P++ + E +L P P + EEP+ A
Sbjct: 10635 TKVPEVPKVAVPEKKVPEAIPPKPESPPPEVFEEPEEVALEEP-PAEVVEEPEPAAPPQV 10693
Query: 231 ------PAPEPQ-PGSQAQTSSLPPTRDP 252
P PE + P A+ LPP + P
Sbjct: 10694 TVPPKKPVPEKKAPAVVAKKPELPPVKVP 10722
Score = 32.7 bits (73), Expect = 0.40
Identities = 22/78 (28%), Positives = 37/78 (47%), Gaps = 3/78 (3%)
Query: 9 LPQPPGTPRKTKMQEEEEVEPEPEMEAEVEPEPNPEEAETESESMPPEESFKEEEVAVAD 68
L P G + K+ E + EP+ E+ + PEE E + E P++ K ++ AV +
Sbjct: 10923 LKVPGGEKKVRKLLPERKPEPKEEVVLKSVLRKRPEEEEPKVE---PKKLEKVKKPAVPE 10979
Query: 69 PSPQETKEAALTSTISLR 86
P P + E T++ R
Sbjct: 10980 PPPPKPVEEVEVPTVTKR 10997
Score = 32.0 bits (71), Expect = 0.68
Identities = 58/263 (22%), Positives = 93/263 (35%), Gaps = 37/263 (14%)
Query: 20 KMQEEEEVEPEPEMEAEVEPEPNPEEAETESESMPPEESFK----EEEVAVADPS----- 70
+ +E EE EPE V+P P EE PP + K EE+V V P
Sbjct: 9778 RYEEHEEYITEPEKPIPVKPVP--EEPVPTKPKAPPAKVLKKAVPEEKVPVPIPKKLKPP 9835
Query: 71 ----PQETKEAALTSTISLRAQGAEISEMNSPSRRVLTWLMKGV-EKVIPQPVHSIT--- 122
P+E K+ I + E ++ P+ +V + V E+ +P P +
Sbjct: 9836 PPKVPEEPKKV-FEEKIRISITKREKEQVTEPAAKVPMKPKRVVAEEKVPVPRKEVAPPV 9894
Query: 123 ---EDPAQILGHGSTGDTGCTDEPNEAL-EAQDTRPGLRLLLWLEQNLERVLP----QPP 174
E P ++ + E L E ++ E+ + V+P + P
Sbjct: 9895 RVPEVPKELEPEEVAFEEEVVTHVEEYLVEEEEEYIHEEEEFITEEEVVPVIPVKVPEVP 9954
Query: 175 KSSEVWRDEPAVA-----TGAASDPAPPGRPQEMGPKLQARETPSLPTPIPLQPKEEPKE 229
+ +P A P P +P+E P L ++ P +P PK+ E
Sbjct: 9955 RKPVPEEKKPVPVPKKKEAPPAKVPEVPKKPEEKVPVLIPKKEKPPPAKVPEVPKKPVPE 10014
Query: 230 APAPEPQPGSQAQTSSLPPTRDP 252
P P P + PP + P
Sbjct: 10015 EKVPVPVP----KKVEAPPAKVP 10033
Score = 30.4 bits (67), Expect = 2.0
Identities = 22/77 (28%), Positives = 32/77 (41%), Gaps = 10/77 (12%)
Query: 167 ERVLPQPPKSSEVWRDEPAVATGAASDPAP-----PGRPQEMGPKLQARETPSLPTPIPL 221
++V P PK EV P P P P P ++ P++ + P P+P+
Sbjct: 9307 KKVEPPAPKVPEV----PKKPVPEEKKPVPVPKKEPAAPPKV-PEVPKKPVPEEKIPVPV 9361
Query: 222 QPKEEPKEAPAPEPQPG 238
K+E A PE Q G
Sbjct: 9362 AKKKEAPPAKVPEVQKG 9378
Score = 29.6 bits (65), Expect = 3.4
Identities = 63/269 (23%), Positives = 95/269 (35%), Gaps = 69/269 (25%)
Query: 6 QRVLPQPPGTPRKTKMQEEEEVEPEPEMEAEVEPEPNPEEAETESESMPPEESFKEEEVA 65
+RV P PP P + EEV P P + +VEP P P+ E + +P E+
Sbjct: 9280 KRVEP-PPKVPELPEKPAPEEVAPVP-IPKKVEP-PAPKVPEVPKKPVPEEKK------- 9329
Query: 66 VADPSPQETKEAALTSTISLRAQGAEISEMNSPSRRVLTWLMKGVEKVIPQPVHSITEDP 125
P P KE A + E+ + P E+ IP PV E P
Sbjct: 9330 ---PVPVPKKEPAAPPKV------PEVPKKPVP------------EEKIPVPVAKKKEAP 9368
Query: 126 AQILGHGSTGDTGCTDEPNEALEAQD---TRPGLRLLLWLEQNLERVLPQPPKSSEVWRD 182
P + E Q T + ++ E++ +P+ PK +V +
Sbjct: 9369 -----------------PAKVPEVQKGVVTEEKITIVTQREESPPPAVPEIPK-KKVPEE 9410
Query: 183 EPAVATGAASDPAPPGRPQEMGPKLQARETPSLPTPIPLQPKEEPKEAPAPEPQPGSQAQ 242
V P PP P + K E ++P P+ K+AP P + +
Sbjct: 9411 RKPVPRKEEEVPPPPKVP-ALPKKPVPEEKVAVPVPV-------AKKAPPPRAEVSKKTV 9462
Query: 243 TSSLPPTRDPARLVAWVLHRLEMALPQPV 271
+ R VA +L A+PQ V
Sbjct: 9463 V-------EEKRFVA--EEKLSFAVPQRV 9482
Score = 28.9 bits (63), Expect = 5.8
Identities = 37/156 (23%), Positives = 61/156 (39%), Gaps = 41/156 (26%)
Query: 5 VQRVLPQPPGTP----------RKTKMQEEEEVEPE--PEMEAEVEPEPNP----EEAE- 47
V+++LP+ P RK +EE +VEP+ +++ PEP P EE E
Sbjct: 10932 VRKLLPERKPEPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEVEV 10991
Query: 48 ---TESESMPPE------------------ESFKEEEVAVADPSPQETKEAALTSTISLR 86
T+ E PE + E EV P P E + + + +++
Sbjct: 10992 PTVTKRERKIPEPTKVPEIKPAIPLPAPEPKPKPEAEVKTIKPPPVEPEPTPIAAPVTVP 11051
Query: 87 AQGAEISEMNSPSRRVL--TWLMKGVEKVIPQPVHS 120
G + +E +P +KGV K P P+ +
Sbjct: 11052 VVGKK-AEAKAPKEEAAKPKGPIKGVPKKTPSPIEA 11086
Score = 28.1 bits (61), Expect = 9.8
Identities = 11/22 (50%), Positives = 16/22 (72%)
Query: 183 EPAVATGAASDPAPPGRPQEMG 204
EP VA + + P+PPG P+E+G
Sbjct: 29229 EPIVARNSFTIPSPPGIPEEVG 29250
>gi|55741677 SET domain containing 1A [Homo sapiens]
Length = 1707
Score = 54.7 bits (130), Expect = 1e-07
Identities = 64/269 (23%), Positives = 97/269 (36%), Gaps = 36/269 (13%)
Query: 16 PRKTKMQEEEEVEPEPEMEA-------EVEPEPNPEEAETES-------------ESMPP 55
PR + EE+E +PE E EA P+ + E +T+ E+
Sbjct: 912 PRPSTPAEEDEDDPEQEKEAGEPGRPGTKPPKRDEERGKTQGKHRKSFALDSEGEEASQE 971
Query: 56 EESFKEEEVAVADPSPQETKEAALTSTISLRAQGAEISEMNSPSRRVLTWLMKGV-EKVI 114
S K+EE D ++ +EA T+ E E +S S+ L G +
Sbjct: 972 SSSEKDEEDDEEDEEDEDREEAVDTTKKETEVSDGEDEESDSSSKCSLYADSDGENDSTS 1031
Query: 115 PQPVHSITEDPAQILGHGSTGDTGCTDEPNEALEAQDTRPGLRLLLWLEQNLERVLPQPP 174
S + + S+ + + E + E ++ RP L P PP
Sbjct: 1032 DSESSSSSSSSSSSSSSSSSSSSSSSSESSSEDEEEEERPAA---------LPSASP-PP 1081
Query: 175 KSSEVWRDEPA---VATGAASDPAPPGRPQEMGPKLQARETPSLPTPIPLQPKEEPKEAP 231
+ V P V A P P QE P A T P PL+P E P P
Sbjct: 1082 REVPVPTPAPVEVPVPERVAGSPVTPLPEQEASPARPAGPTEESPPSAPLRPPEPPAGPP 1141
Query: 232 APEPQPGSQAQT--SSLPPTRDPARLVAW 258
AP P+P + + LPP + + V++
Sbjct: 1142 APAPRPDERPSSPIPLLPPPKKRRKTVSF 1170
Score = 38.5 bits (88), Expect = 0.007
Identities = 55/254 (21%), Positives = 80/254 (31%), Gaps = 38/254 (14%)
Query: 9 LPQPPGTPRKTKMQEEEEVEPEPEMEAEVE------PEPNPEEAETESESMPPEESFKEE 62
LP P P + P PE P P EE T P S
Sbjct: 413 LPPEPSRPTDQDYRPPASEAPPPEPPEPGGGGGGGGPSPEREEVRTSPRPASPARS---- 468
Query: 63 EVAVADPSPQETKEAALTSTISLRAQGAEISEMNSPSRRVLTWLMKGVEKVIPQPVHSIT 122
P+P+ T E+ + S + + I + R ++L E+
Sbjct: 469 ----GSPAPETTNESVPFAQHS--SLDSRIEMLLKEQRSKFSFLASDTEEE--------E 514
Query: 123 EDPAQILGHGSTGDTGCTDEPNEALEAQDTRPGLRLLLWLEQNLERVLPQPPKSSEVWRD 182
E+ + +LG TG ++ P+ + T P N E V P R+
Sbjct: 515 ENSSMVLGARDTG----SEVPSGSGHGPCTPPPA------PANFEDVAPTGSGEPGATRE 564
Query: 183 EPAVATGAASDPAPPGRPQEMGPKLQARETPSLPTPIPLQPKEEPKEAPAPEPQPGSQAQ 242
P + P G E+ + P PTP P++ P P P P P A
Sbjct: 565 SPKANGQNQASPCSSGDDMEISDDDRGGSPPPAPTP----PQQPPPPPPPPPPPPPYLAS 620
Query: 243 TSSLPPTRDPARLV 256
P PA L+
Sbjct: 621 LPLGYPPHQPAYLL 634
Score = 32.7 bits (73), Expect = 0.40
Identities = 21/66 (31%), Positives = 27/66 (40%), Gaps = 3/66 (4%)
Query: 218 PIPLQPKEEPKEAPAPEPQPGSQAQTSSLPPTRDPARLVAWVLHRLEMALPQPVLHGKIG 277
P P P EE ++ P E + G + + PP RD R HR AL G+
Sbjct: 912 PRPSTPAEEDEDDPEQEKEAGEPGRPGTKPPKRDEERGKTQGKHRKSFALDS---EGEEA 968
Query: 278 EQEPDS 283
QE S
Sbjct: 969 SQESSS 974
Score = 32.0 bits (71), Expect = 0.68
Identities = 59/293 (20%), Positives = 105/293 (35%), Gaps = 38/293 (12%)
Query: 17 RKTKMQEEEEVEPEPEMEAEVEPEPNPEEAETESESMPPEESFKEEEVAV---ADPSPQE 73
+++ +++EE + E E + + E + + ETE EES + ++ +D
Sbjct: 970 QESSSEKDEEDDEEDEEDEDREEAVDTTKKETEVSDGEDEESDSSSKCSLYADSDGENDS 1029
Query: 74 TKEAALTSTISLRAQGAEISEMNSPSRRVLTWLMKGVEKVIPQPVHSITEDPAQILGHGS 133
T ++ +S+ S + + S +S S + E+ P + S + P ++
Sbjct: 1030 TSDSESSSSSSSSSSSSSSSSSSSSSSSSESSSEDEEEEERPAALPSASPPPREV----- 1084
Query: 134 TGDTGCTDEPNEALEAQDTRPGLRLLLWLEQNLERVLP-----QPPKSSEVWRDEPAVAT 188
T P E + + G + EQ P + P S+ + EP
Sbjct: 1085 ---PVPTPAPVE-VPVPERVAGSPVTPLPEQEASPARPAGPTEESPPSAPLRPPEPP--- 1137
Query: 189 GAASDPAPPGRPQE--------MGPKLQARETPSL--------PTPIPLQPKEEPKEAPA 232
A PAP RP E + P + R+T S P P P P + PA
Sbjct: 1138 --AGPPAPAPRPDERPSSPIPLLPPPKKRRKTVSFSAIEVVPAPEPPPATPPQAKFPGPA 1195
Query: 233 PEPQPGSQAQTSSLPPTRDPARLVAWVLHRLEMALPQPVLHGKIGEQEPDSPG 285
P +T P + + +W + G++ E+E PG
Sbjct: 1196 SRKAPRGVERTIRNLPLDHASLVKSWPEEVSRGGRSRAGGRGRLTEEEEAEPG 1248
Score = 31.6 bits (70), Expect = 0.89
Identities = 21/72 (29%), Positives = 30/72 (41%), Gaps = 2/72 (2%)
Query: 10 PQPPGTPRKTKMQEEEEVEPEPEMEAEVEPEPNPEEAETESESMPPE--ESFKEEEVAVA 67
P+P P +EV PE+ EP P++ + + E E E +EEE +
Sbjct: 1318 PEPVPAPAALFSSPADEVLEAPEVVVAEAEEPKPQQLQQQREEGEEEGEEEGEEEEEESS 1377
Query: 68 DPSPQETKEAAL 79
D S E AL
Sbjct: 1378 DSSSSSDGEGAL 1389
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 50.8 bits (120), Expect = 1e-06
Identities = 59/254 (23%), Positives = 86/254 (33%), Gaps = 20/254 (7%)
Query: 13 PGTPRKTKMQEEEEVEP----EPEMEAEVEPEPNPEEAETESESMPPEESFKEEEVAVAD 68
P TP++ +E P EP EP P ++ + P + K +
Sbjct: 358 PTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKE 417
Query: 69 PSPQETKEAALTSTISLRAQGAEISEMNSPSRRVLTWLMKGVEKVIPQPVHSITEDPAQI 128
PSP TKE A T+ + +P T + +P + ++PA
Sbjct: 418 PSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPT 477
Query: 129 LGHGSTGDTGCTDEPNEALEAQDTRPGLRLLLWLEQNLERVLPQPPKSSEVWRDEPAVAT 188
+ T P + T P E+ L P+ P + +EPA T
Sbjct: 478 TPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEE-LAPTTPEEPTPTTP--EEPAPTT 534
Query: 189 GAASDPAPPGRPQEMGPKLQARETPSLPTP------IPLQPK-------EEPKEAPAPEP 235
A+ P P P PK A TP P P P PK +EP +P
Sbjct: 535 PKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKP 594
Query: 236 QPGSQAQTSSLPPT 249
P A T++ PT
Sbjct: 595 APKELAPTTTKEPT 608
Score = 45.4 bits (106), Expect = 6e-05
Identities = 60/263 (22%), Positives = 80/263 (30%), Gaps = 30/263 (11%)
Query: 10 PQPPGTPRKTKMQEEEEVEPEPEMEAEVEPEPNPEE--AETESESMPPEESFKEEEVAVA 67
P P P T +E EP EP P + A T + P +
Sbjct: 319 PTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTK 378
Query: 68 DPSPQETKEAALTSTISLRAQGAEISEM----------------------NSPSRRVLTW 105
+PSP KE A T+T S E + +P T
Sbjct: 379 EPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTT 438
Query: 106 LMKGVEKVIPQPVHSITEDPAQILGHGSTGDTGCTDEPNEALEAQDTRPGLRLLLWLEQN 165
K +P + ++PA T P E T P +L +
Sbjct: 439 PKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTP-KKLTPTTPEK 497
Query: 166 LERVLPQPPKSSEVWRDEPAVATGAASDPAPPGRPQEMGPKLQARETPSLPTPIPLQPKE 225
L P+ P + +E A T P P P PK A TP P P PK
Sbjct: 498 LAPTTPEKP--APTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPK--EPAPTTPK- 552
Query: 226 EPKEAPAPEPQPGSQAQTSSLPP 248
EP EP P + +T+ P
Sbjct: 553 EPAPTTPKEPAPTTPKETAPTTP 575
Score = 44.7 bits (104), Expect = 1e-04
Identities = 67/289 (23%), Positives = 93/289 (32%), Gaps = 36/289 (12%)
Query: 10 PQPPGTPRKTKMQEEEEVEP-EPEMEAEVEPEPNPEEAETESESMPPEESF-----KEEE 63
P P P T +E P EP EP P T+S P+E K
Sbjct: 256 PTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTT----TKSAPTTPKEPAPTTPKKPAP 311
Query: 64 VAVADPSPQETKEAALTSTISLRAQGAEISEMNSPSRRVLTWLMKGVEKVIPQPVHSITE 123
+P+P KE T T A + +P T K +P + +
Sbjct: 312 TTPKEPAPTTPKEPTPT-TPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPK 370
Query: 124 DPAQILGHGSTGDTGCTDEPNEALEAQDTRPGLRLLLWLEQNLERVLPQPPKSSEVWRDE 183
+PA + T P A T + P KS+ E
Sbjct: 371 EPAPTTTKEPSPTTPKEPAPTTTKSAPTT-------------TKEPAPTTTKSAPTTPKE 417
Query: 184 PAVATGAASDPAPPGRPQEMGPKLQARETPSLPTP-IPLQPKEEPKEAPAP----EPQPG 238
P+ T P P P PK A TP P P P +P + PAP EP P
Sbjct: 418 PSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPT 477
Query: 239 SQAQTSSLPPTRDPARLVAWVLHRLEMALPQ---PVLHGKIGEQEPDSP 284
+ +T+ PT P +L +L P+ P ++ P+ P
Sbjct: 478 TPKETA---PT-TPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEP 522
Score = 43.9 bits (102), Expect = 2e-04
Identities = 63/276 (22%), Positives = 88/276 (31%), Gaps = 39/276 (14%)
Query: 13 PGTPRKTKMQEEEEVEP----EPEMEAEVEPEPNPEEAETESESMPPEESFKEEEVAVA- 67
P TP K EE+ P EP EP P +A + P + +E
Sbjct: 500 PTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTP 559
Query: 68 -DPSPQETKEAALTSTISLRAQGAEISEMNSPSRRVLTWLMKGVEKVIPQPVHSITEDPA 126
+P+P KE A T+ + +P + L K +P + + PA
Sbjct: 560 KEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTK---EPTSTTCDKPA 616
Query: 127 QILGHGSTGDTGCTDEPNEALEAQDTRPGLRLLLWLEQNLERVLPQP-PKS--------- 176
G+ T P E T P L++ +P PK
Sbjct: 617 PTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGP 676
Query: 177 SEVWRDEPAVATGAASDPAPPGRPQEMGPKLQARETPSLPTP----------------IP 220
+ D+PA T + P P P PK A TP P P I
Sbjct: 677 TSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIH 736
Query: 221 LQPKEEPKEAPAPEPQP---GSQAQTSSLPPTRDPA 253
P E E A EP P + + +P T+ PA
Sbjct: 737 KSPDESTPELSA-EPTPKALENSPKEPGVPTTKTPA 771
Score = 42.0 bits (97), Expect = 7e-04
Identities = 53/232 (22%), Positives = 71/232 (30%), Gaps = 44/232 (18%)
Query: 31 PEMEAEVEPEPN-PEEAETESESMPPEESFKEEEVAVADPSPQETKEAALTSTISLRAQG 89
P + EP P P+E + + P + K +P+P TK A T
Sbjct: 208 PALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTT--------- 258
Query: 90 AEISEMNSPSRRVLTWLMKGVEKVIPQPVHSITEDPAQILGHGS-------TGDTGCTDE 142
P T + +P + T++PA + T
Sbjct: 259 --------PKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPA 310
Query: 143 PNEALEAQDTRPGLRLLLWLEQNLERVLPQPPKSSEVWRDEPAVATGAASDPAPPGRPQE 202
P E T P + P PK EPA T P P +P
Sbjct: 311 PTTPKEPAPTTP------------KEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAP 358
Query: 203 MGPKLQARETPSLPTPIPLQPKEEPKEAPAPEPQPGSQAQTSSLP-PTRDPA 253
PK A TP P P +EP EP P T S P T++PA
Sbjct: 359 TTPKEPAPTTPKEPAP---TTTKEPSPTTPKEPAP---TTTKSAPTTTKEPA 404
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 50.8 bits (120), Expect = 1e-06
Identities = 59/254 (23%), Positives = 86/254 (33%), Gaps = 20/254 (7%)
Query: 13 PGTPRKTKMQEEEEVEP----EPEMEAEVEPEPNPEEAETESESMPPEESFKEEEVAVAD 68
P TP++ +E P EP EP P ++ + P + K +
Sbjct: 399 PTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKE 458
Query: 69 PSPQETKEAALTSTISLRAQGAEISEMNSPSRRVLTWLMKGVEKVIPQPVHSITEDPAQI 128
PSP TKE A T+ + +P T + +P + ++PA
Sbjct: 459 PSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPT 518
Query: 129 LGHGSTGDTGCTDEPNEALEAQDTRPGLRLLLWLEQNLERVLPQPPKSSEVWRDEPAVAT 188
+ T P + T P E+ L P+ P + +EPA T
Sbjct: 519 TPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEE-LAPTTPEEPTPTTP--EEPAPTT 575
Query: 189 GAASDPAPPGRPQEMGPKLQARETPSLPTP------IPLQPK-------EEPKEAPAPEP 235
A+ P P P PK A TP P P P PK +EP +P
Sbjct: 576 PKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKP 635
Query: 236 QPGSQAQTSSLPPT 249
P A T++ PT
Sbjct: 636 APKELAPTTTKEPT 649
Score = 45.4 bits (106), Expect = 6e-05
Identities = 60/263 (22%), Positives = 80/263 (30%), Gaps = 30/263 (11%)
Query: 10 PQPPGTPRKTKMQEEEEVEPEPEMEAEVEPEPNPEE--AETESESMPPEESFKEEEVAVA 67
P P P T +E EP EP P + A T + P +
Sbjct: 360 PTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTK 419
Query: 68 DPSPQETKEAALTSTISLRAQGAEISEM----------------------NSPSRRVLTW 105
+PSP KE A T+T S E + +P T
Sbjct: 420 EPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTT 479
Query: 106 LMKGVEKVIPQPVHSITEDPAQILGHGSTGDTGCTDEPNEALEAQDTRPGLRLLLWLEQN 165
K +P + ++PA T P E T P +L +
Sbjct: 480 PKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTP-KKLTPTTPEK 538
Query: 166 LERVLPQPPKSSEVWRDEPAVATGAASDPAPPGRPQEMGPKLQARETPSLPTPIPLQPKE 225
L P+ P + +E A T P P P PK A TP P P PK
Sbjct: 539 LAPTTPEKP--APTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPK--EPAPTTPK- 593
Query: 226 EPKEAPAPEPQPGSQAQTSSLPP 248
EP EP P + +T+ P
Sbjct: 594 EPAPTTPKEPAPTTPKETAPTTP 616
Score = 44.7 bits (104), Expect = 1e-04
Identities = 67/289 (23%), Positives = 93/289 (32%), Gaps = 36/289 (12%)
Query: 10 PQPPGTPRKTKMQEEEEVEP-EPEMEAEVEPEPNPEEAETESESMPPEESF-----KEEE 63
P P P T +E P EP EP P T+S P+E K
Sbjct: 297 PTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTT----TKSAPTTPKEPAPTTPKKPAP 352
Query: 64 VAVADPSPQETKEAALTSTISLRAQGAEISEMNSPSRRVLTWLMKGVEKVIPQPVHSITE 123
+P+P KE T T A + +P T K +P + +
Sbjct: 353 TTPKEPAPTTPKEPTPT-TPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPK 411
Query: 124 DPAQILGHGSTGDTGCTDEPNEALEAQDTRPGLRLLLWLEQNLERVLPQPPKSSEVWRDE 183
+PA + T P A T + P KS+ E
Sbjct: 412 EPAPTTTKEPSPTTPKEPAPTTTKSAPTT-------------TKEPAPTTTKSAPTTPKE 458
Query: 184 PAVATGAASDPAPPGRPQEMGPKLQARETPSLPTP-IPLQPKEEPKEAPAP----EPQPG 238
P+ T P P P PK A TP P P P +P + PAP EP P
Sbjct: 459 PSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPT 518
Query: 239 SQAQTSSLPPTRDPARLVAWVLHRLEMALPQ---PVLHGKIGEQEPDSP 284
+ +T+ PT P +L +L P+ P ++ P+ P
Sbjct: 519 TPKETA---PT-TPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEP 563
Score = 43.9 bits (102), Expect = 2e-04
Identities = 63/276 (22%), Positives = 88/276 (31%), Gaps = 39/276 (14%)
Query: 13 PGTPRKTKMQEEEEVEP----EPEMEAEVEPEPNPEEAETESESMPPEESFKEEEVAVA- 67
P TP K EE+ P EP EP P +A + P + +E
Sbjct: 541 PTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTP 600
Query: 68 -DPSPQETKEAALTSTISLRAQGAEISEMNSPSRRVLTWLMKGVEKVIPQPVHSITEDPA 126
+P+P KE A T+ + +P + L K +P + + PA
Sbjct: 601 KEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTK---EPTSTTCDKPA 657
Query: 127 QILGHGSTGDTGCTDEPNEALEAQDTRPGLRLLLWLEQNLERVLPQP-PKS--------- 176
G+ T P E T P L++ +P PK
Sbjct: 658 PTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGP 717
Query: 177 SEVWRDEPAVATGAASDPAPPGRPQEMGPKLQARETPSLPTP----------------IP 220
+ D+PA T + P P P PK A TP P P I
Sbjct: 718 TSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIH 777
Query: 221 LQPKEEPKEAPAPEPQP---GSQAQTSSLPPTRDPA 253
P E E A EP P + + +P T+ PA
Sbjct: 778 KSPDESTPELSA-EPTPKALENSPKEPGVPTTKTPA 812
Score = 42.0 bits (97), Expect = 7e-04
Identities = 53/232 (22%), Positives = 71/232 (30%), Gaps = 44/232 (18%)
Query: 31 PEMEAEVEPEPN-PEEAETESESMPPEESFKEEEVAVADPSPQETKEAALTSTISLRAQG 89
P + EP P P+E + + P + K +P+P TK A T
Sbjct: 249 PALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTT--------- 299
Query: 90 AEISEMNSPSRRVLTWLMKGVEKVIPQPVHSITEDPAQILGHGS-------TGDTGCTDE 142
P T + +P + T++PA + T
Sbjct: 300 --------PKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPA 351
Query: 143 PNEALEAQDTRPGLRLLLWLEQNLERVLPQPPKSSEVWRDEPAVATGAASDPAPPGRPQE 202
P E T P + P PK EPA T P P +P
Sbjct: 352 PTTPKEPAPTTP------------KEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAP 399
Query: 203 MGPKLQARETPSLPTPIPLQPKEEPKEAPAPEPQPGSQAQTSSLP-PTRDPA 253
PK A TP P P +EP EP P T S P T++PA
Sbjct: 400 TTPKEPAPTTPKEPAP---TTTKEPSPTTPKEPAP---TTTKSAPTTTKEPA 445
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 50.8 bits (120), Expect = 1e-06
Identities = 59/254 (23%), Positives = 86/254 (33%), Gaps = 20/254 (7%)
Query: 13 PGTPRKTKMQEEEEVEP----EPEMEAEVEPEPNPEEAETESESMPPEESFKEEEVAVAD 68
P TP++ +E P EP EP P ++ + P + K +
Sbjct: 451 PTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKE 510
Query: 69 PSPQETKEAALTSTISLRAQGAEISEMNSPSRRVLTWLMKGVEKVIPQPVHSITEDPAQI 128
PSP TKE A T+ + +P T + +P + ++PA
Sbjct: 511 PSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPT 570
Query: 129 LGHGSTGDTGCTDEPNEALEAQDTRPGLRLLLWLEQNLERVLPQPPKSSEVWRDEPAVAT 188
+ T P + T P E+ L P+ P + +EPA T
Sbjct: 571 TPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEE-LAPTTPEEPTPTTP--EEPAPTT 627
Query: 189 GAASDPAPPGRPQEMGPKLQARETPSLPTP------IPLQPK-------EEPKEAPAPEP 235
A+ P P P PK A TP P P P PK +EP +P
Sbjct: 628 PKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKP 687
Query: 236 QPGSQAQTSSLPPT 249
P A T++ PT
Sbjct: 688 APKELAPTTTKEPT 701
Score = 45.4 bits (106), Expect = 6e-05
Identities = 60/263 (22%), Positives = 80/263 (30%), Gaps = 30/263 (11%)
Query: 10 PQPPGTPRKTKMQEEEEVEPEPEMEAEVEPEPNPEE--AETESESMPPEESFKEEEVAVA 67
P P P T +E EP EP P + A T + P +
Sbjct: 412 PTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTK 471
Query: 68 DPSPQETKEAALTSTISLRAQGAEISEM----------------------NSPSRRVLTW 105
+PSP KE A T+T S E + +P T
Sbjct: 472 EPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTT 531
Query: 106 LMKGVEKVIPQPVHSITEDPAQILGHGSTGDTGCTDEPNEALEAQDTRPGLRLLLWLEQN 165
K +P + ++PA T P E T P +L +
Sbjct: 532 PKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTP-KKLTPTTPEK 590
Query: 166 LERVLPQPPKSSEVWRDEPAVATGAASDPAPPGRPQEMGPKLQARETPSLPTPIPLQPKE 225
L P+ P + +E A T P P P PK A TP P P PK
Sbjct: 591 LAPTTPEKP--APTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPK--EPAPTTPK- 645
Query: 226 EPKEAPAPEPQPGSQAQTSSLPP 248
EP EP P + +T+ P
Sbjct: 646 EPAPTTPKEPAPTTPKETAPTTP 668
Score = 44.7 bits (104), Expect = 1e-04
Identities = 67/289 (23%), Positives = 93/289 (32%), Gaps = 36/289 (12%)
Query: 10 PQPPGTPRKTKMQEEEEVEP-EPEMEAEVEPEPNPEEAETESESMPPEESF-----KEEE 63
P P P T +E P EP EP P T+S P+E K
Sbjct: 349 PTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTT----TKSAPTTPKEPAPTTPKKPAP 404
Query: 64 VAVADPSPQETKEAALTSTISLRAQGAEISEMNSPSRRVLTWLMKGVEKVIPQPVHSITE 123
+P+P KE T T A + +P T K +P + +
Sbjct: 405 TTPKEPAPTTPKEPTPT-TPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPK 463
Query: 124 DPAQILGHGSTGDTGCTDEPNEALEAQDTRPGLRLLLWLEQNLERVLPQPPKSSEVWRDE 183
+PA + T P A T + P KS+ E
Sbjct: 464 EPAPTTTKEPSPTTPKEPAPTTTKSAPTT-------------TKEPAPTTTKSAPTTPKE 510
Query: 184 PAVATGAASDPAPPGRPQEMGPKLQARETPSLPTP-IPLQPKEEPKEAPAP----EPQPG 238
P+ T P P P PK A TP P P P +P + PAP EP P
Sbjct: 511 PSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPT 570
Query: 239 SQAQTSSLPPTRDPARLVAWVLHRLEMALPQ---PVLHGKIGEQEPDSP 284
+ +T+ PT P +L +L P+ P ++ P+ P
Sbjct: 571 TPKETA---PT-TPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEP 615
Score = 43.9 bits (102), Expect = 2e-04
Identities = 63/276 (22%), Positives = 88/276 (31%), Gaps = 39/276 (14%)
Query: 13 PGTPRKTKMQEEEEVEP----EPEMEAEVEPEPNPEEAETESESMPPEESFKEEEVAVA- 67
P TP K EE+ P EP EP P +A + P + +E
Sbjct: 593 PTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTP 652
Query: 68 -DPSPQETKEAALTSTISLRAQGAEISEMNSPSRRVLTWLMKGVEKVIPQPVHSITEDPA 126
+P+P KE A T+ + +P + L K +P + + PA
Sbjct: 653 KEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTK---EPTSTTCDKPA 709
Query: 127 QILGHGSTGDTGCTDEPNEALEAQDTRPGLRLLLWLEQNLERVLPQP-PKS--------- 176
G+ T P E T P L++ +P PK
Sbjct: 710 PTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGP 769
Query: 177 SEVWRDEPAVATGAASDPAPPGRPQEMGPKLQARETPSLPTP----------------IP 220
+ D+PA T + P P P PK A TP P P I
Sbjct: 770 TSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIH 829
Query: 221 LQPKEEPKEAPAPEPQP---GSQAQTSSLPPTRDPA 253
P E E A EP P + + +P T+ PA
Sbjct: 830 KSPDESTPELSA-EPTPKALENSPKEPGVPTTKTPA 864
Score = 42.0 bits (97), Expect = 7e-04
Identities = 53/232 (22%), Positives = 71/232 (30%), Gaps = 44/232 (18%)
Query: 31 PEMEAEVEPEPN-PEEAETESESMPPEESFKEEEVAVADPSPQETKEAALTSTISLRAQG 89
P + EP P P+E + + P + K +P+P TK A T
Sbjct: 301 PALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTT--------- 351
Query: 90 AEISEMNSPSRRVLTWLMKGVEKVIPQPVHSITEDPAQILGHGS-------TGDTGCTDE 142
P T + +P + T++PA + T
Sbjct: 352 --------PKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPA 403
Query: 143 PNEALEAQDTRPGLRLLLWLEQNLERVLPQPPKSSEVWRDEPAVATGAASDPAPPGRPQE 202
P E T P + P PK EPA T P P +P
Sbjct: 404 PTTPKEPAPTTP------------KEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAP 451
Query: 203 MGPKLQARETPSLPTPIPLQPKEEPKEAPAPEPQPGSQAQTSSLP-PTRDPA 253
PK A TP P P +EP EP P T S P T++PA
Sbjct: 452 TTPKEPAPTTPKEPAP---TTTKEPSPTTPKEPAP---TTTKSAPTTTKEPA 497
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 50.8 bits (120), Expect = 1e-06
Identities = 59/254 (23%), Positives = 86/254 (33%), Gaps = 20/254 (7%)
Query: 13 PGTPRKTKMQEEEEVEP----EPEMEAEVEPEPNPEEAETESESMPPEESFKEEEVAVAD 68
P TP++ +E P EP EP P ++ + P + K +
Sbjct: 492 PTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKE 551
Query: 69 PSPQETKEAALTSTISLRAQGAEISEMNSPSRRVLTWLMKGVEKVIPQPVHSITEDPAQI 128
PSP TKE A T+ + +P T + +P + ++PA
Sbjct: 552 PSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPT 611
Query: 129 LGHGSTGDTGCTDEPNEALEAQDTRPGLRLLLWLEQNLERVLPQPPKSSEVWRDEPAVAT 188
+ T P + T P E+ L P+ P + +EPA T
Sbjct: 612 TPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEE-LAPTTPEEPTPTTP--EEPAPTT 668
Query: 189 GAASDPAPPGRPQEMGPKLQARETPSLPTP------IPLQPK-------EEPKEAPAPEP 235
A+ P P P PK A TP P P P PK +EP +P
Sbjct: 669 PKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKP 728
Query: 236 QPGSQAQTSSLPPT 249
P A T++ PT
Sbjct: 729 APKELAPTTTKEPT 742
Score = 45.4 bits (106), Expect = 6e-05
Identities = 60/263 (22%), Positives = 80/263 (30%), Gaps = 30/263 (11%)
Query: 10 PQPPGTPRKTKMQEEEEVEPEPEMEAEVEPEPNPEE--AETESESMPPEESFKEEEVAVA 67
P P P T +E EP EP P + A T + P +
Sbjct: 453 PTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTK 512
Query: 68 DPSPQETKEAALTSTISLRAQGAEISEM----------------------NSPSRRVLTW 105
+PSP KE A T+T S E + +P T
Sbjct: 513 EPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTT 572
Query: 106 LMKGVEKVIPQPVHSITEDPAQILGHGSTGDTGCTDEPNEALEAQDTRPGLRLLLWLEQN 165
K +P + ++PA T P E T P +L +
Sbjct: 573 PKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTP-KKLTPTTPEK 631
Query: 166 LERVLPQPPKSSEVWRDEPAVATGAASDPAPPGRPQEMGPKLQARETPSLPTPIPLQPKE 225
L P+ P + +E A T P P P PK A TP P P PK
Sbjct: 632 LAPTTPEKP--APTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPK--EPAPTTPK- 686
Query: 226 EPKEAPAPEPQPGSQAQTSSLPP 248
EP EP P + +T+ P
Sbjct: 687 EPAPTTPKEPAPTTPKETAPTTP 709
Score = 44.7 bits (104), Expect = 1e-04
Identities = 67/289 (23%), Positives = 93/289 (32%), Gaps = 36/289 (12%)
Query: 10 PQPPGTPRKTKMQEEEEVEP-EPEMEAEVEPEPNPEEAETESESMPPEESF-----KEEE 63
P P P T +E P EP EP P T+S P+E K
Sbjct: 390 PTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTT----TKSAPTTPKEPAPTTPKKPAP 445
Query: 64 VAVADPSPQETKEAALTSTISLRAQGAEISEMNSPSRRVLTWLMKGVEKVIPQPVHSITE 123
+P+P KE T T A + +P T K +P + +
Sbjct: 446 TTPKEPAPTTPKEPTPT-TPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPK 504
Query: 124 DPAQILGHGSTGDTGCTDEPNEALEAQDTRPGLRLLLWLEQNLERVLPQPPKSSEVWRDE 183
+PA + T P A T + P KS+ E
Sbjct: 505 EPAPTTTKEPSPTTPKEPAPTTTKSAPTT-------------TKEPAPTTTKSAPTTPKE 551
Query: 184 PAVATGAASDPAPPGRPQEMGPKLQARETPSLPTP-IPLQPKEEPKEAPAP----EPQPG 238
P+ T P P P PK A TP P P P +P + PAP EP P
Sbjct: 552 PSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPT 611
Query: 239 SQAQTSSLPPTRDPARLVAWVLHRLEMALPQ---PVLHGKIGEQEPDSP 284
+ +T+ PT P +L +L P+ P ++ P+ P
Sbjct: 612 TPKETA---PT-TPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEP 656
Score = 43.9 bits (102), Expect = 2e-04
Identities = 63/276 (22%), Positives = 88/276 (31%), Gaps = 39/276 (14%)
Query: 13 PGTPRKTKMQEEEEVEP----EPEMEAEVEPEPNPEEAETESESMPPEESFKEEEVAVA- 67
P TP K EE+ P EP EP P +A + P + +E
Sbjct: 634 PTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTP 693
Query: 68 -DPSPQETKEAALTSTISLRAQGAEISEMNSPSRRVLTWLMKGVEKVIPQPVHSITEDPA 126
+P+P KE A T+ + +P + L K +P + + PA
Sbjct: 694 KEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTK---EPTSTTCDKPA 750
Query: 127 QILGHGSTGDTGCTDEPNEALEAQDTRPGLRLLLWLEQNLERVLPQP-PKS--------- 176
G+ T P E T P L++ +P PK
Sbjct: 751 PTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGP 810
Query: 177 SEVWRDEPAVATGAASDPAPPGRPQEMGPKLQARETPSLPTP----------------IP 220
+ D+PA T + P P P PK A TP P P I
Sbjct: 811 TSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIH 870
Query: 221 LQPKEEPKEAPAPEPQP---GSQAQTSSLPPTRDPA 253
P E E A EP P + + +P T+ PA
Sbjct: 871 KSPDESTPELSA-EPTPKALENSPKEPGVPTTKTPA 905
Score = 42.0 bits (97), Expect = 7e-04
Identities = 53/232 (22%), Positives = 71/232 (30%), Gaps = 44/232 (18%)
Query: 31 PEMEAEVEPEPN-PEEAETESESMPPEESFKEEEVAVADPSPQETKEAALTSTISLRAQG 89
P + EP P P+E + + P + K +P+P TK A T
Sbjct: 342 PALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTT--------- 392
Query: 90 AEISEMNSPSRRVLTWLMKGVEKVIPQPVHSITEDPAQILGHGS-------TGDTGCTDE 142
P T + +P + T++PA + T
Sbjct: 393 --------PKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPA 444
Query: 143 PNEALEAQDTRPGLRLLLWLEQNLERVLPQPPKSSEVWRDEPAVATGAASDPAPPGRPQE 202
P E T P + P PK EPA T P P +P
Sbjct: 445 PTTPKEPAPTTP------------KEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAP 492
Query: 203 MGPKLQARETPSLPTPIPLQPKEEPKEAPAPEPQPGSQAQTSSLP-PTRDPA 253
PK A TP P P +EP EP P T S P T++PA
Sbjct: 493 TTPKEPAPTTPKEPAP---TTTKEPSPTTPKEPAP---TTTKSAPTTTKEPA 538
>gi|149773456 hypothetical protein LOC643314 [Homo sapiens]
Length = 1427
Score = 50.1 bits (118), Expect = 2e-06
Identities = 75/302 (24%), Positives = 114/302 (37%), Gaps = 45/302 (14%)
Query: 10 PQPPGTPRKTKMQEEEEVEPEPEMEAEVEPE------PNPEEAETESESMP-PEESFKEE 62
P+ P +P EE P + EP P PEE + ++P PEES
Sbjct: 1101 PEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEES---A 1157
Query: 63 EVAVADPSPQETKEAALT-----STISLRAQGAEISEMNSPSRRVLT-WLMKGVEKVIPQ 116
AVA P+P+E+ A + S A A + E SP+ V T M +
Sbjct: 1158 SAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVATLEEFTS 1217
Query: 117 PVHSI--TEDPAQILGHGSTGDTGCTDEPNEALEAQDTRPGLRLLLWLEQNLERVLPQPP 174
P S+ +E+PA + S + + P A+ + + + L P
Sbjct: 1218 PAASVPTSEEPASLAAAVSNPEEPTS--PAAAVPTLEEPTSSAAAVLTPEELSS-----P 1270
Query: 175 KSSEVWRDEPAVATGAASDPAPPGRPQEMGPKLQARETP--SLPTP-IPLQPKE--EPKE 229
+S +EPA A S+ P P P + P S+PTP +P P P E
Sbjct: 1271 AASVPTPEEPASPAAAVSNLEEPASPAAAVPTPEVAAIPAASVPTPEVPAIPAAAVPPME 1330
Query: 230 APAPEPQP--GSQAQTSSLPPTRDPARLV-------AWVLHRLE------MALPQPVLHG 274
+P P G A T S+P + + ++ W+ L+ + VLHG
Sbjct: 1331 EVSPIGVPFLGVSAHTDSVPISEEGTPVLEEASSTGMWIKEDLDSLVFGIKEVTSTVLHG 1390
Query: 275 KI 276
K+
Sbjct: 1391 KV 1392
Score = 40.0 bits (92), Expect = 0.002
Identities = 58/258 (22%), Positives = 94/258 (36%), Gaps = 55/258 (21%)
Query: 41 PNPEEAETESESMPPEESFKEEEVAVADPSPQETKEAALTSTISLRAQGAEISEMNSPSR 100
P+PEE + + PE + VA P P E + + S +SL + + +++P R
Sbjct: 852 PSPEEGTSIAAVPAPEGT---AVVAALVPFPHE--DILVASIVSLEEEDVTAAAVSAPER 906
Query: 101 RVLTWLMKGVEKVIPQPVHSITEDPAQILGHGSTGDTGCTDEPNEALEAQDTRPGLRLLL 160
+P S+ E A + S +T A+ A T+ G+ +
Sbjct: 907 AT-----------VPAVTVSVPEGTAAVAAVSSPEETA------PAVAAAITQEGMSAVA 949
Query: 161 -----WL---------EQNLERVLPQPPKSSEVWRDEPAVATGAASDPAPPGRPQEMGPK 206
W E++ P P ++ +EP A S P P P P
Sbjct: 950 GFSPEWAALAITVPITEEDGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPT 1009
Query: 207 LQARETPSLPTPIPLQPKEEPKEAPAPEPQPGSQAQTSSLPPTRDPARLVAWVLHRLEMA 266
+ +P+ P P +P P PE +P S A +++P +P A A
Sbjct: 1010 PEEPTSPAAAVPTPEEPTSPAAAVPPPE-EPTSPA--AAVPTPEEPTSPAA--------A 1058
Query: 267 LPQPVLHGKIGEQEPDSP 284
+P P +EP SP
Sbjct: 1059 VPTP--------EEPTSP 1068
Score = 39.3 bits (90), Expect = 0.004
Identities = 57/254 (22%), Positives = 79/254 (31%), Gaps = 42/254 (16%)
Query: 10 PQPPGTPRKTKMQEEEEVEPEPEMEAEVEPE------PNPEEAETESESMPPEESFKEEE 63
P+ P T EE P + EP P PEE + + ++PP E +
Sbjct: 984 PEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPE--EPTS 1041
Query: 64 VAVADPSPQE-TKEAALTSTISLRAQGAEISEMNSPSRRVLTWLMKGVEKVIPQPVHSIT 122
A A P+P+E T AA T E SP+ V T E P
Sbjct: 1042 PAAAVPTPEEPTSPAAAVPTPE---------EPTSPAAAVPT----PEEPTSPAAAVPTP 1088
Query: 123 EDPAQILGHGSTGDTGCTDEPNEALEAQDTRPGLRLLLWLEQNLERVLPQPPKSSEVWRD 182
E+P T +EP A T P P ++ +
Sbjct: 1089 EEPTSPAAAVPT-----PEEPTSPAAAVPTPEE---------------PASPAAAVPTPE 1128
Query: 183 EPAVATGAASDPAPPGRPQEMGPKLQARETPSLPTPIPLQPKEEPKEAPAPEPQPGSQAQ 242
EPA A P P P P + + ++ P P + P P A
Sbjct: 1129 EPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAV 1188
Query: 243 TSSLPPTRDPARLV 256
++L PA V
Sbjct: 1189 VATLEEPTSPAASV 1202
Score = 37.7 bits (86), Expect = 0.012
Identities = 30/112 (26%), Positives = 41/112 (36%), Gaps = 10/112 (8%)
Query: 171 PQPPKSSEVWRDEPAVATGAASDPAPPGRPQEMGPKLQARETPSLPTPIPLQP------- 223
P P ++ +EP A P P P P + +P+ P P +P
Sbjct: 1039 PTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAV 1098
Query: 224 --KEEPKEAPAPEPQPGSQAQTSSLPPT-RDPARLVAWVLHRLEMALPQPVL 272
EEP A P P A ++ PT +PA A V E A P P +
Sbjct: 1099 PTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAV 1150
Score = 36.2 bits (82), Expect = 0.036
Identities = 69/309 (22%), Positives = 110/309 (35%), Gaps = 69/309 (22%)
Query: 4 WVQRVLPQPPGTPRKTKMQEEEEVE-PEPEMEAEVEPEPNPEEAETESESMP-PEE---- 57
W+ VL +P T +++ + P PE + P PE + +P P E
Sbjct: 827 WIP-VLQRPSRTAAVPTVKDALDAALPSPEEGTSIAAVPAPEGTAVVAALVPFPHEDILV 885
Query: 58 ----SFKEEEVAVADPSPQETKEAALTSTISLRAQGAEISEMNSPSRRVLTWLMKGVEKV 113
S +EE+V A S E + T+S+ A ++ ++SP E+
Sbjct: 886 ASIVSLEEEDVTAAAVSAPE-RATVPAVTVSVPEGTAAVAAVSSP------------EET 932
Query: 114 IPQPVHSITEDPAQILGHGS------------TGDTGCTDEPN------EALEAQDTRPG 155
P +IT++ + S T + G + P A E DT
Sbjct: 933 APAVAAAITQEGMSAVAGFSPEWAALAITVPITEEDGTPEGPVTPATTVHAPEEPDTA-A 991
Query: 156 LRLLLWLEQNLERVLPQPPKSSEVWRDEPAVATGAASDPAPPGRPQEMGPKLQARETPSL 215
+R+ E P P ++ +EP A P P P P + +P+
Sbjct: 992 VRVSTPEE-------PASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAA 1044
Query: 216 PTPIPLQPKEEPKEAPAPEPQPGSQAQTSSLPPTRDPARLVAWVLHRLEMALPQPVLHGK 275
P P +P P PE +P S A +++P +P A A+P P
Sbjct: 1045 AVPTPEEPTSPAAAVPTPE-EPTSPA--AAVPTPEEPTSPAA--------AVPTP----- 1088
Query: 276 IGEQEPDSP 284
+EP SP
Sbjct: 1089 ---EEPTSP 1094
Score = 35.0 bits (79), Expect = 0.080
Identities = 29/114 (25%), Positives = 43/114 (37%), Gaps = 19/114 (16%)
Query: 171 PQPPKSSEVWRDEPAVATGAASDPAPPGRPQEMGPKLQARETPSLPTPIPLQPKEEPKEA 230
P P ++ +EP A P P P P + +P+ P P +P
Sbjct: 1013 PTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAV 1072
Query: 231 PAPEPQPGSQAQTSSLPPTRDPARLVAWVLHRLEMALPQPVLHGKIGEQEPDSP 284
P PE +P S A +++P +P A A+P P +EP SP
Sbjct: 1073 PTPE-EPTSPA--AAVPTPEEPTSPAA--------AVPTP--------EEPTSP 1107
Score = 35.0 bits (79), Expect = 0.080
Identities = 30/114 (26%), Positives = 44/114 (38%), Gaps = 6/114 (5%)
Query: 171 PQPPKSSEVWRDEPAVATGAASDPAPPGRPQEMGPKLQARETPSLPTPIPLQPKEEPKEA 230
P P ++ +EP A P P P P + +P+ P P +P
Sbjct: 1026 PTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAV 1085
Query: 231 PAPEPQPGSQAQTSSLPPTRDPARLVAWVLHRLEMALPQPVLHGKIGEQEPDSP 284
P PE +P S A +++P +P A V E A P + +EP SP
Sbjct: 1086 PTPE-EPTSPA--AAVPTPEEPTSPAAAVPTPEEPASPAAAVP---TPEEPASP 1133
>gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo sapiens]
Length = 2524
Score = 48.5 bits (114), Expect = 7e-06
Identities = 78/283 (27%), Positives = 105/283 (37%), Gaps = 34/283 (12%)
Query: 12 PPGTPRKTKMQEEEEVEPEPEMEAEVEPEPNPEEAETESESMPPEESFKEEEVAVADPSP 71
PP P++ K EEE P +E E +P P E ++ EE K E A+ P
Sbjct: 819 PPVVPKEEK---EEETAAAPPVEEGEEQKP-PAAEELAVDTGKAEEPVKSECTEEAEEGP 874
Query: 72 QETKEAALTSTISLRAQGAEISEMNSPSRRVLTWLMKGVEKVIPQPVHSITEDPAQILGH 131
+ K+A + A AE E S R T G PQ S A +
Sbjct: 875 AKGKDAEAAEATAEGALKAEKKE--GGSGRATTAKSSGA----PQDSDSSATCSADEVDE 928
Query: 132 GSTGDTGCTDEPNEALEAQDTRPGLRLL----LWLEQNLERVLPQPPKSSEVWRDEPAVA 187
GD P +L P L L+Q +R PP ++V EP
Sbjct: 929 AEGGDKNRLLSPRPSLLTPTGDPRANASPQKPLDLKQLKQRAAAIPPIVTKV--HEPPRE 986
Query: 188 TGAASDPAPPG--RPQEMGPKLQARETP-SLP---TPIPLQPKEEPKEAPAPEPQPGSQA 241
A + PAPP PQ + P+ A + P S P + P P + KEA P P A
Sbjct: 987 DAAPTKPAPPAPPPPQNLQPESDAPQQPGSSPRGKSRSPAPPAD--KEAEKPVFFPAFAA 1044
Query: 242 QTSSLPPTRDPARLVAWVLHRLEMALPQPVLHGKIGEQEPDSP 284
+ LP DP W LP PV ++ + P +P
Sbjct: 1045 EAQKLP--GDPP---CWT-----SGLPFPVPPREVIKASPHAP 1077
Score = 29.3 bits (64), Expect = 4.4
Identities = 30/105 (28%), Positives = 37/105 (35%), Gaps = 18/105 (17%)
Query: 184 PAVATGAASD-----PAPPGRPQEMGPKLQARETPSLPTPIPLQ--PKEEPKEAPAPEPQ 236
P+ T AA D P PP GP P P P + P E AP P P
Sbjct: 752 PSPHTEAAKDTGQNGPKPPATLGADGPPPGPPTPPPEDIPAPTEPTPASEATGAPTPPPA 811
Query: 237 PGSQAQTSSLPPTRDPARLVAWVLHRLEMALPQPVLHGKIGEQEP 281
P S + + P + E A PV G+ EQ+P
Sbjct: 812 PPSPSAPPPVVPKEEKEE---------ETAAAPPVEEGE--EQKP 845
Score = 28.9 bits (63), Expect = 5.8
Identities = 24/96 (25%), Positives = 35/96 (36%), Gaps = 25/96 (26%)
Query: 183 EPAVATGAASDPAPPGRPQEMGPKLQARETPSLPT------------------------P 218
E A A A+ + P G + +T S+P+ P
Sbjct: 719 EEAEALHASGNEVPRGECSGPATVNNSSDTESIPSPHTEAAKDTGQNGPKPPATLGADGP 778
Query: 219 IPLQPKEEPKEAPAP-EPQPGSQAQTSSLPPTRDPA 253
P P P++ PAP EP P S+A + PP P+
Sbjct: 779 PPGPPTPPPEDIPAPTEPTPASEATGAPTPPPAPPS 814
Score = 28.5 bits (62), Expect = 7.5
Identities = 19/49 (38%), Positives = 22/49 (44%), Gaps = 2/49 (4%)
Query: 170 LPQPPKSSEVWRDEPAVATGAASDPAPPGRPQEMGPKLQARETPSLPTP 218
LP P EV + P +A APPG P +G AR P LP P
Sbjct: 1060 LPFPVPPREVIKASPHAPDPSAFSYAPPGHPLPLGLHDTAR--PVLPRP 1106
Score = 28.1 bits (61), Expect = 9.8
Identities = 12/60 (20%), Positives = 29/60 (48%)
Query: 17 RKTKMQEEEEVEPEPEMEAEVEPEPNPEEAETESESMPPEESFKEEEVAVADPSPQETKE 76
R+ K Q++++ + + + + + +P P + E + + E +EE+ V + KE
Sbjct: 489 RRGKSQQQQQQQQQQQQQQQQQPMPRSSQEEKDEKEKEKEAEKEEEKPEVENDKEDLLKE 548
>gi|117938768 GNAS complex locus alex [Homo sapiens]
Length = 626
Score = 48.1 bits (113), Expect = 9e-06
Identities = 41/113 (36%), Positives = 51/113 (45%), Gaps = 20/113 (17%)
Query: 171 PQP-PKSSEVWRDEPAVATGAASDPAP---PGRPQEMGPKL-----------QARETPSL 215
PQP P +P G P P PGRP + P L Q R+T L
Sbjct: 375 PQPIPTPGRPLTPQPIPTPGRPLTPQPIQMPGRPLRLPPPLRLLRPGQPMSPQLRQTQGL 434
Query: 216 PTPIPLQPKEEPKEAPAP-EP-QPGSQAQTSSLPP---TRDPARLVAWVLHRL 263
P P PL P +PK A P +P PG A++ S PP +R P RL+ +L RL
Sbjct: 435 PLPQPLLPPGQPKSAGRPLQPLPPGPDARSISDPPAPRSRLPIRLLRGLLARL 487
Score = 35.0 bits (79), Expect = 0.080
Identities = 23/69 (33%), Positives = 30/69 (43%), Gaps = 8/69 (11%)
Query: 192 SDPAPPGRPQEM---GPKLQARE--TPSLPTPIPLQPKEEPKEAPA---PEPQPGSQAQT 243
+DP PPG+PQ + G LQ + TP P IP + +P P P P PG
Sbjct: 316 TDPLPPGQPQRIPLPGQPLQPQPILTPGQPQKIPTPGQHQPILTPGHSQPIPTPGQPLPP 375
Query: 244 SSLPPTRDP 252
+P P
Sbjct: 376 QPIPTPGRP 384
Score = 28.1 bits (61), Expect = 9.8
Identities = 20/84 (23%), Positives = 31/84 (36%), Gaps = 2/84 (2%)
Query: 174 PKSSEVWRDEPAVATGAASDPAPPGRPQEMGPKLQARETPSLPTPIPLQPKEEPKE--AP 231
P + + +P + G PG+ Q + ++ P+ P+P QP P P
Sbjct: 328 PLPGQPLQPQPILTPGQPQKIPTPGQHQPILTPGHSQPIPTPGQPLPPQPIPTPGRPLTP 387
Query: 232 APEPQPGSQAQTSSLPPTRDPARL 255
P P PG + P RL
Sbjct: 388 QPIPTPGRPLTPQPIQMPGRPLRL 411
>gi|210032580 SET domain containing 1B [Homo sapiens]
Length = 1923
Score = 47.4 bits (111), Expect = 2e-05
Identities = 60/242 (24%), Positives = 94/242 (38%), Gaps = 44/242 (18%)
Query: 23 EEEEVEPEPEMEAEVEPEPNPEEAETESESMPPEESFKEEEVAVADPSPQETKEAALTST 82
EEE V + E +E ES S S ++EE VA +E +E + +
Sbjct: 1096 EEETVSIVTSKAEATSSSESSESSEFESSSESSPSSSEDEEEVVAREEEEEEEEEEMVAE 1155
Query: 83 ISLRAQGAEISEMN------SPSRRVLTWLMKG------VEKVIPQPVHSITEDPAQILG 130
S+ + G E E + +P + L E V P+ S+ ++P +G
Sbjct: 1156 ESMASAGPEDFEQDGEEAALAPGAPAVDSLGMEEEVDIETEAVAPEERPSMLDEPPLPVG 1215
Query: 131 HGSTGDTGCTDEPNEALEAQDTRPGLRLLLWLEQNLERVLPQPPKSSEVWRDEPAVATGA 190
+EP ++ E + PGL ++ + P+PP + EV
Sbjct: 1216 ---------VEEPADSREPPE-EPGLS-----QEGAMLLSPEPP-AKEV----------E 1249
Query: 191 ASDPAPPGRPQEMGPKLQARETPSLPTPIPLQ---PKEEPKEAPAPEPQP-GSQAQTSSL 246
A P P R E L+ P + P+PLQ P P P+P P+P + A S+
Sbjct: 1250 ARPPLSPERAPEHD--LEVEPEPPMMLPLPLQPPLPPPRPPRPPSPPPEPETTDASHPSV 1307
Query: 247 PP 248
PP
Sbjct: 1308 PP 1309
Score = 46.6 bits (109), Expect = 3e-05
Identities = 59/250 (23%), Positives = 100/250 (40%), Gaps = 33/250 (13%)
Query: 22 QEEEEVEPEPEMEAEVEPEPNPEEAETESESMPPEESFKEEEVAVADPSPQET------K 75
+EEE E E E + + + + +E+E + E E+ +++E D +ET K
Sbjct: 1050 EEEEAEEEEEEEDDDDDDSDDRDESENDDEDTALSEASEKDE---GDSDEEETVSIVTSK 1106
Query: 76 EAALTSTISLRAQGAEISEMNSPSRRVLTWLMKGVEKVIPQPVHSITEDPAQILGHGSTG 135
A +S+ S + E S +SPS + E+V+ + E+ +++ S
Sbjct: 1107 AEATSSSESSESSEFESSSESSPSS------SEDEEEVVAREEEE-EEEEEEMVAEESMA 1159
Query: 136 DTGCTDEPNEALEAQDTRPGLRLL--LWLEQNLE-RVLPQPPKSSEVWRDEPAVATG--- 189
G D + EA PG + L +E+ ++ P+ DEP + G
Sbjct: 1160 SAGPEDFEQDGEEAA-LAPGAPAVDSLGMEEEVDIETEAVAPEERPSMLDEPPLPVGVEE 1218
Query: 190 ---AASDPAPPGRPQE----MGPKLQARETPSLPTPIPLQPKEEPKEAPAPEPQPGSQAQ 242
+ P PG QE + P+ A+E + P PL P+ P+ EP+P
Sbjct: 1219 PADSREPPEEPGLSQEGAMLLSPEPPAKEVEARP---PLSPERAPEHDLEVEPEPPMMLP 1275
Query: 243 TSSLPPTRDP 252
PP P
Sbjct: 1276 LPLQPPLPPP 1285
Score = 37.0 bits (84), Expect = 0.021
Identities = 57/242 (23%), Positives = 94/242 (38%), Gaps = 49/242 (20%)
Query: 22 QEEEEVEPEPEMEAEVEPEPNP-EEAETESESMPPEESFKEEEVAVADPSPQET------ 74
+EEEE E E E E + + + + +E+E + E E+ +++E D +ET
Sbjct: 1049 EEEEEAEEEEEEEDDDDDDSDDRDESENDDEDTALSEASEKDE---GDSDEEETVSIVTS 1105
Query: 75 KEAALTSTISLRAQGAEISEMNSPSRRVLTWLMKGVEKVIPQPVHSITEDPAQILGHGST 134
K A +S+ S + E S +SPS + E+V+ + E+ +++ S
Sbjct: 1106 KAEATSSSESSESSEFESSSESSPSSS------EDEEEVVAREEEE-EEEEEEMVAEESM 1158
Query: 135 GDTGCTDEPNEALEAQDTRPGLRLLLWLEQNLERVLPQPPKSSEVWRDEPAVATGAASDP 194
G D + EA PG P S +E + T A
Sbjct: 1159 ASAGPEDFEQDGEEAA-LAPGA----------------PAVDSLGMEEEVDIETEAV--- 1198
Query: 195 APPGRPQEMGPKLQARETPSLPTPIPLQPKEEPKEAPAPEPQPGSQAQTSSLPPTRDPAR 254
AP RP + + P LP + EEP ++ P +PG + + L PA+
Sbjct: 1199 APEERPSML-------DEPPLPVGV-----EEPADSREPPEEPGLSQEGAMLLSPEPPAK 1246
Query: 255 LV 256
V
Sbjct: 1247 EV 1248
Score = 34.7 bits (78), Expect = 0.10
Identities = 23/69 (33%), Positives = 24/69 (34%), Gaps = 7/69 (10%)
Query: 184 PAVATGAASDPAPPGRPQEMGPKLQARETPSLPTPIPLQPKEEPKEAPAPEPQPGSQAQT 243
P+V P PPG P P P P P PL P P P P P A T
Sbjct: 672 PSVLAPTLPLPPPPGFPPLPPPPPPPPPQPGFPMPPPLPP-------PPPPPPPAHPAVT 724
Query: 244 SSLPPTRDP 252
PP P
Sbjct: 725 VPPPPLPAP 733
Score = 32.3 bits (72), Expect = 0.52
Identities = 73/327 (22%), Positives = 104/327 (31%), Gaps = 65/327 (19%)
Query: 6 QRVLPQPPGTPRKTKMQEEEEVEPEPEMEAEV---------------EPEPNPEEAETES 50
+ V +PP +P + + + EVEPEP M + P P PE +
Sbjct: 1246 KEVEARPPLSPERAP-EHDLEVEPEPPMMLPLPLQPPLPPPRPPRPPSPPPEPETTDASH 1304
Query: 51 ESMPPEESFKEEEVAVADPSPQET-------KEAALTSTISLRAQGAEISEMNSPSRRVL 103
S+PPE +A+ P T ++ T T+ G S +
Sbjct: 1305 PSVPPE--------PLAEDHPPHTPGLCGSLAKSQSTETVPATPGGEPPLSGGSSGLSLS 1356
Query: 104 TWLMKGVEKVIPQPVHSITEDPAQILGHGSTGDTGCTDEPNEAL---------EAQDTRP 154
+ + G P P S++ T EP+ L +D R
Sbjct: 1357 SPQVPGSPFSYPAPSPSLSSGGLPRTPGRDFSFTPTFSEPSGPLLLPVCPLPTGRRDERS 1416
Query: 155 G-----LRLLLWLEQNLERVLPQPPKSSEVWRDE--------PAVATGAASDPAP----P 197
G + L L L LP P V R + P + AS P P P
Sbjct: 1417 GPLASPVLLETGLPLPLPLPLPLPLALPAVLRAQARAPTPLPPLLPAPLASCPPPMKRKP 1476
Query: 198 GRPQEMGPKLQARETPSLPTPIPLQPKEEPKEAPAPEPQPGSQAQTSSLPPTRDPARLVA 257
GRP+ P + + + P + P E P Q QT P T DP R V
Sbjct: 1477 GRPRRSPPSMLSLDGPLVRPPAGAALGRELLLLP-------GQPQTPVFPSTHDP-RTVT 1528
Query: 258 WVLHRLEMALPQPVLHGKIGEQEPDSP 284
+ P P L + P P
Sbjct: 1529 LDFRNAGIPAPPPPLPPQPPPPPPPPP 1555
Score = 31.6 bits (70), Expect = 0.89
Identities = 69/283 (24%), Positives = 93/283 (32%), Gaps = 42/283 (14%)
Query: 13 PGTPRKTKMQEEEEVEPEPEMEAEVE--------PEPNPEEAETESESMPPEESFKEEEV 64
PG P + EEEV+ E E A E P P E +S P E +E
Sbjct: 1177 PGAPAVDSLGMEEEVDIETEAVAPEERPSMLDEPPLPVGVEEPADSREPPEEPGLSQEGA 1236
Query: 65 AVADPSPQETKEAALTSTISLRAQGAEISEMNSPSRRVLTWLMKGVEKVIPQPVHSITED 124
+ P P + A RA ++ P + L + P S +
Sbjct: 1237 MLLSPEPPAKEVEARPPLSPERAPEHDLEVEPEPPMMLPLPLQPPLPPPRPPRPPSPPPE 1296
Query: 125 PAQILGHGSTGDTGCTDEPNEALEAQD---TRPGLRLLLWLEQNLERVLPQPPKSSEVWR 181
P T D P E L A+D PGL L Q+ E V P
Sbjct: 1297 P-------ETTDASHPSVPPEPL-AEDHPPHTPGLCGSLAKSQSTETVPATP-------G 1341
Query: 182 DEPAVATGAA----SDPAPPGRP---QEMGPKLQARETPSLP------TPIPLQPKEEPK 228
EP ++ G++ S P PG P P L + P P TP +P P
Sbjct: 1342 GEPPLSGGSSGLSLSSPQVPGSPFSYPAPSPSLSSGGLPRTPGRDFSFTPTFSEP-SGPL 1400
Query: 229 EAPAPEPQPGSQAQTSSLPPTRDPARLVAWVLHRLEMALPQPV 271
P G + + S P P L + L + LP P+
Sbjct: 1401 LLPVCPLPTGRRDERSG--PLASPVLLETGLPLPLPLPLPLPL 1441
>gi|33356148 formin-like 1 [Homo sapiens]
Length = 1100
Score = 45.8 bits (107), Expect = 5e-05
Identities = 48/188 (25%), Positives = 72/188 (38%), Gaps = 8/188 (4%)
Query: 73 ETKEAALTSTISLRAQGAEISEMNSPSRRVLTWLMKGVEKVIPQPVHSITEDPAQILGHG 132
ETK A L L+ Q A ++E + + +EK + Q + +
Sbjct: 392 ETKNAVLEHMEELQEQVALLTERLRDAENESMAKIAELEKQLSQARKELETLRERFSEST 451
Query: 133 STGDTGCTDEPNEALEAQDTRPG---LRLLLWLEQNLERVLPQPPKSSEVWRDEPAVATG 189
+ G + EP +A A TRP L++ E+ L R+L P + + AVAT
Sbjct: 452 AMGASRRPPEPEKAPPAAPTRPSALELKVEELEEKGLIRILRGPGDAVSIEILPVAVATP 511
Query: 190 AASDPAPPGRPQ-----EMGPKLQARETPSLPTPIPLQPKEEPKEAPAPEPQPGSQAQTS 244
+ D PG P ++ P + + P P PL P+EAP P S
Sbjct: 512 SGGDAPTPGVPTGSPSPDLAPAAEPAPGAAPPPPPPLPGLPSPQEAPPSAPPQAPPLPGS 571
Query: 245 SLPPTRDP 252
PP P
Sbjct: 572 PEPPPAPP 579
Score = 33.1 bits (74), Expect = 0.31
Identities = 49/218 (22%), Positives = 73/218 (33%), Gaps = 28/218 (12%)
Query: 28 EPEPEMEAEV-EPEPNPEEAETESESMPPEESFKEEEVAVAD---PSPQETKEAALTSTI 83
+ E E A++ E E +A E E++ E F E A P P++ AA T
Sbjct: 417 DAENESMAKIAELEKQLSQARKELETL--RERFSESTAMGASRRPPEPEKAPPAAPTRPS 474
Query: 84 SLRAQGAEISEMNSPSRRVLTWLMKGVEKVIPQPVHSITEDPAQILGHGSTGDTGCTDEP 143
+L + E+ E KG+ +++ P +++ + + +G T
Sbjct: 475 ALELKVEELEE-------------KGLIRILRGPGDAVSIEILPVAVATPSGGDAPTPGV 521
Query: 144 NEALEAQDTRPGLRLLLWLEQNLERVLPQPPKSSEVWRDEPAVATGAASDPAPPGRPQEM 203
+ D P LP P E P A P PP P
Sbjct: 522 PTGSPSPDLAPAAEPAPGAAPPPPPPLPGLPSPQEAPPSAPPQAPPLPGSPEPPPAPPLP 581
Query: 204 GPKLQARETPSLPTPIPLQPKEE---PKEAPAPEPQPG 238
G + P P P P P + P P P P PG
Sbjct: 582 G------DLPPPPPPPPPPPGTDGPVPPPPPPPPPPPG 613
>gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo sapiens]
Length = 2462
Score = 45.4 bits (106), Expect = 6e-05
Identities = 78/284 (27%), Positives = 106/284 (37%), Gaps = 35/284 (12%)
Query: 12 PPGTPRKTKMQEEEEVEPEPEMEAEVEPEPNPEEAETESESMPPEESFKEEEVAVADPSP 71
PP P++ K EEE P +E E +P P E ++ EE K E A+ P
Sbjct: 802 PPVVPKEEK---EEETAAAPPVEEGEEQKP-PAAEELAVDTGKAEEPVKSECTEEAEEGP 857
Query: 72 QETKEAALTSTISLRAQGAEISEMNSPSRRVLTWLMKGVEKVIPQPVHSITEDPAQILGH 131
+ K+A + A AE E S R T G PQ S A +
Sbjct: 858 AKGKDAEAAEATAEGALKAEKKE--GGSGRATTAKSSGA----PQDSDSSATCSADEVDE 911
Query: 132 GSTGDTGCTDEPNEALEAQDTRPGLRLL----LWLEQNLERVLPQPP-KSSEVWRDEPAV 186
GD P +L P L L+Q +R PP + ++V EP
Sbjct: 912 AEGGDKNRLLSPRPSLLTPTGDPRANASPQKPLDLKQLKQRAAAIPPIQVTKV--HEPPR 969
Query: 187 ATGAASDPAPPG--RPQEMGPKLQARETP-SLP---TPIPLQPKEEPKEAPAPEPQPGSQ 240
A + PAPP PQ + P+ A + P S P + P P + KEA P P
Sbjct: 970 EDAAPTKPAPPAPPPPQNLQPESDAPQQPGSSPRGKSRSPAPPAD--KEAEKPVFFPAFA 1027
Query: 241 AQTSSLPPTRDPARLVAWVLHRLEMALPQPVLHGKIGEQEPDSP 284
A+ LP DP W LP PV ++ + P +P
Sbjct: 1028 AEAQKLP--GDPP---CWT-----SGLPFPVPPREVIKASPHAP 1061
Score = 33.1 bits (74), Expect = 0.31
Identities = 20/70 (28%), Positives = 29/70 (41%), Gaps = 10/70 (14%)
Query: 171 PQPPKSSEVWRDEPAVATGAASDPAPPGRPQEMGPKLQARETPSLPTPIPLQPKEEPKEA 230
P PP EP A+ A P PP P +PS P P+ + ++E + A
Sbjct: 766 PTPPPEDIPAPTEPTPASEATGAPTPPPAPP----------SPSAPPPVVPKEEKEEETA 815
Query: 231 PAPEPQPGSQ 240
AP + G +
Sbjct: 816 AAPPVEEGEE 825
Score = 29.3 bits (64), Expect = 4.4
Identities = 30/105 (28%), Positives = 37/105 (35%), Gaps = 18/105 (17%)
Query: 184 PAVATGAASD-----PAPPGRPQEMGPKLQARETPSLPTPIPLQ--PKEEPKEAPAPEPQ 236
P+ T AA D P PP GP P P P + P E AP P P
Sbjct: 735 PSPHTEAAKDTGQNGPKPPATLGADGPPPGPPTPPPEDIPAPTEPTPASEATGAPTPPPA 794
Query: 237 PGSQAQTSSLPPTRDPARLVAWVLHRLEMALPQPVLHGKIGEQEP 281
P S + + P + E A PV G+ EQ+P
Sbjct: 795 PPSPSAPPPVVPKEEKEE---------ETAAAPPVEEGE--EQKP 828
Score = 28.5 bits (62), Expect = 7.5
Identities = 19/49 (38%), Positives = 22/49 (44%), Gaps = 2/49 (4%)
Query: 170 LPQPPKSSEVWRDEPAVATGAASDPAPPGRPQEMGPKLQARETPSLPTP 218
LP P EV + P +A APPG P +G AR P LP P
Sbjct: 1044 LPFPVPPREVIKASPHAPDPSAFSYAPPGHPLPLGLHDTAR--PVLPRP 1090
Score = 28.1 bits (61), Expect = 9.8
Identities = 12/60 (20%), Positives = 29/60 (48%)
Query: 17 RKTKMQEEEEVEPEPEMEAEVEPEPNPEEAETESESMPPEESFKEEEVAVADPSPQETKE 76
R+ K Q++++ + + + + + +P P + E + + E +EE+ V + KE
Sbjct: 489 RRGKSQQQQQQQQQQQQQQQQQPMPRSSQEEKDEKEKEKEAEKEEEKPEVENDKEDLLKE 548
>gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens]
Length = 825
Score = 45.4 bits (106), Expect = 6e-05
Identities = 60/244 (24%), Positives = 90/244 (36%), Gaps = 39/244 (15%)
Query: 28 EPEPEMEAEVEPEPNPEEAETESESMPPEESFKEE-----EVAVADPSPQETKEAALTST 82
E E + + E + EEA E +S EE+ EE ++ A +P + A S
Sbjct: 486 ETPAEARSPLSEETSAEEAHAEVQSPLAEETTAEEASAEIQLLAAIEAPADETPAEAQSP 545
Query: 83 ISLRAQGAEI-SEMNSPSRRVLTWLMKGVEKVIPQPVHSITEDPAQILGHGSTGDTGCTD 141
+S E +E+ SPS KGV SI E P ++
Sbjct: 546 LSEETSAEEAPAEVQSPSA-------KGV---------SIEEAPLEL-----------QP 578
Query: 142 EPNEALEAQDTRPGLRLLLWLEQNLERVLP--QPPKSSEVWRD-EPAVATGAASDPAPPG 198
E A++ ++LL E + E QPP + E + +P A A ++ PP
Sbjct: 579 PSGEETTAEEASAAIQLLAATEASAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPP- 637
Query: 199 RPQEMGP-KLQARETPSLPTPIPLQPKEEPKEAPAPEPQPGSQAQTSSLPPTRDPARLVA 257
P E P ++Q P + P EE P P + A+ SLP P
Sbjct: 638 -PAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQSLPAEETPIEETL 696
Query: 258 WVLH 261
+H
Sbjct: 697 AAVH 700
Score = 41.6 bits (96), Expect = 9e-04
Identities = 32/107 (29%), Positives = 50/107 (46%), Gaps = 14/107 (13%)
Query: 26 EVEPEPEMEAEVEPEPNP-EEAETESESMPPEESFKEEEVAVADPSPQETKEAALTSTIS 84
EV+P P EA E +P P EEA E +S+P EE+ EE +A P +
Sbjct: 657 EVQPPPAEEAPAEVQPPPAEEAPAEVQSLPAEETPIEETLAAVHSPPAD----------D 706
Query: 85 LRAQGAEISEMNSPSRRVLTW---LMKGVEKVIPQPVHSITEDPAQI 128
+ A+ A + + + P+ +LT + + +V P P ED A +
Sbjct: 707 VPAEEASVDKHSPPADLLLTEEFPIGEASAEVSPPPSEQTPEDEALV 753
Score = 36.6 bits (83), Expect = 0.028
Identities = 33/122 (27%), Positives = 51/122 (41%), Gaps = 7/122 (5%)
Query: 26 EVEPEPEMEAEVEPEPNP-EEAETESESMPPEESFKEEEVAVADPSPQETK----EAALT 80
EV+P P EA E +P P EEA E + P EE+ E + A+ +P E + E A
Sbjct: 609 EVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPA 668
Query: 81 STISLRAQGAEISEMNSPSRRVLTWLMKGVEKVIPQPVHSITEDPAQILGHGSTGDTGCT 140
A+ A + P+ T + + + V P + + A + H D T
Sbjct: 669 EVQPPPAEEAPAEVQSLPAEE--TPIEETLAAVHSPPADDVPAEEASVDKHSPPADLLLT 726
Query: 141 DE 142
+E
Sbjct: 727 EE 728
Score = 35.4 bits (80), Expect = 0.061
Identities = 58/264 (21%), Positives = 105/264 (39%), Gaps = 24/264 (9%)
Query: 12 PPGTPRKTKMQEEEEVEPEPEMEAEVEPEPNP-----EEAETESESMPPEESFKEEEVAV 66
PP + ++ E+ +A +E +P P EEA + E EE+ + + +
Sbjct: 369 PPPAEKSPSVELLGEIRSPSAQKAPIEVQPLPAEGALEEAPAKVEPPTVEETLADVQPLL 428
Query: 67 ADPSP-QETKEAALTSTISLRAQGAEISEMNSPSRRVLTWLMKGVE-KVIPQPVHSITED 124
+ +P +E +E L++ + A+ A +E SP + T E +++ E
Sbjct: 429 PEEAPREEARELQLSTAMETPAEEAP-TEFQSPLPKETTAEEASAEIQLLAATEPPADET 487
Query: 125 PAQI---LGHGSTGDTGCTDEPN---EALEAQDTRPGLRLLLWLEQNLER--VLPQPPKS 176
PA+ L ++ + + + E A++ ++LL +E + Q P S
Sbjct: 488 PAEARSPLSEETSAEEAHAEVQSPLAEETTAEEASAEIQLLAAIEAPADETPAEAQSPLS 547
Query: 177 SEVWRDE-PA-----VATGAASDPAPPGRPQEMGPKLQARETPSLPTPIPLQPKEEPKEA 230
E +E PA A G + + AP G + A E S + + +EA
Sbjct: 548 EETSAEEAPAEVQSPSAKGVSIEEAPLELQPPSGEETTAEEA-SAAIQLLAATEASAEEA 606
Query: 231 PAP-EPQPGSQAQTSSLPPTRDPA 253
PA +P P +A PP + A
Sbjct: 607 PAEVQPPPAEEAPAEVQPPPAEEA 630
Score = 33.9 bits (76), Expect = 0.18
Identities = 58/238 (24%), Positives = 92/238 (38%), Gaps = 25/238 (10%)
Query: 26 EVEPEP--EMEAEVEPEPNPEEAETESESMPPEESFKEEEVAVADPSPQETKEAALTSTI 83
E+EP + A+++P P EEA ++E P EE+ + + + + E A +++
Sbjct: 256 EIEPPSTEKFPAKIQP-PLVEEATAKAEPRPAEETHVQVQPSTEETPDAEAATAVAENSV 314
Query: 84 SLRAQGAE-------ISEMNSPSRRVLTWLMKGVEKVIPQPVHSITED-PAQILGHGSTG 135
++ AE +E+ PS + E + P S +E+ PA+IL
Sbjct: 315 KVQPPPAEEAPLVEFPAEIQPPSAEESPSVELLAEILPPSAEESPSEEPPAEIL------ 368
Query: 136 DTGCTDEPNEALEAQDTRPGLRLLLWLEQNL--ERVLPQPPKSSEVWRDEPAVATGAASD 193
P+ L + P + Q L E L + P E E +A
Sbjct: 369 PPPAEKSPSVELLGEIRSPSAQKAPIEVQPLPAEGALEEAPAKVEPPTVEETLAD--VQP 426
Query: 194 PAPPGRPQEMGPKLQ---ARETPSLPTPIPLQPKEEPKEAPAPEPQPGSQAQTSSLPP 248
P P+E +LQ A ETP+ P Q PKE A E Q ++ PP
Sbjct: 427 LLPEEAPREEARELQLSTAMETPAEEAPTEFQ-SPLPKETTAEEASAEIQLLAATEPP 483
>gi|157738619 smoothelin-like 1 [Homo sapiens]
Length = 512
Score = 45.4 bits (106), Expect = 6e-05
Identities = 51/234 (21%), Positives = 82/234 (35%), Gaps = 17/234 (7%)
Query: 24 EEEVEPEPEMEAEVEPEPNPEEAETESESMPPEESFKEEEVAVADPSPQETKEAALTSTI 83
+EE + EP+ E E E+ + E + PE K + P P+ T E T
Sbjct: 133 KEETKSEPKEAEEKESTLASEKQKAEEKEAKPESGQKADANDRDKPEPKATVEEEDAKTA 192
Query: 84 SLRAQGAEISEMNSPSRRVLTWLMKGVEK--VIPQPVHSITEDP--AQILGHGSTGDTGC 139
S G P + K + V+ + ++P + HG+ +
Sbjct: 193 SQEETGQRKECSTEPKEKATDEEAKAESQKAVVEDEAKAEPKEPDGKEEAKHGAKEEADA 252
Query: 140 TDEPNEALEAQDTRPGLRLLLWLEQNLERVLPQPPKSSEVWRDEPAVATGAASDPAPPGR 199
+E +A EA+ P +E+ E P S E W + P TG + + G
Sbjct: 253 KEEAEDAEEAEPGSPSEEQEQDVEKEPEGGAGVIPSSPEEWPESP---TGEGHNLSTDG- 308
Query: 200 PQEMGPKLQA------RETPSLPTPIPLQPKEEPKEAPAPEPQPGSQAQTSSLP 247
+GP A + S P+ +P P E P E P + + P
Sbjct: 309 ---LGPDCVASGQTSPSASESSPSDVPQSPPESPSSGEKKEKAPERRVSAPARP 359
Score = 42.0 bits (97), Expect = 7e-04
Identities = 56/245 (22%), Positives = 93/245 (37%), Gaps = 40/245 (16%)
Query: 18 KTKMQEEEEVEPEPEMEAEVEPEPNPEEAET----------ESESMPPEESFKEEEVAVA 67
+ K++ + E + + EAE++ E +E T E P+E+ ++E +
Sbjct: 93 EVKVESQREAGGKEDAEAELKKEDGEKEETTVGSQEMTGRKEETKSEPKEAEEKESTLAS 152
Query: 68 DPSPQETKEAALTSTISLRAQGAEISEMNSPSRRVLTWLMKGVEKVIPQPVHSITEDPAQ 127
+ E KEA S Q A+ ++ + P+P ++ E+ A+
Sbjct: 153 EKQKAEEKEAKPES-----GQKADANDRDK-----------------PEPKATVEEEDAK 190
Query: 128 ILGHGSTGD-TGCTDEPNE-ALEAQDTRPGLRLLLWLEQNLERVLPQPPKSSEVWRDEPA 185
TG C+ EP E A + + + ++ E E P + ++ E A
Sbjct: 191 TASQEETGQRKECSTEPKEKATDEEAKAESQKAVVEDEAKAEPKEPDGKEEAKHGAKEEA 250
Query: 186 VATGAASD--PAPPGRPQEMGPKLQARETPSLPTPIPLQPKEEPKEAPAPEPQPGSQAQT 243
A A D A PG P E + +E IP P+E P E+P E G T
Sbjct: 251 DAKEEAEDAEEAEPGSPSEEQEQDVEKEPEGGAGVIPSSPEEWP-ESPTGE---GHNLST 306
Query: 244 SSLPP 248
L P
Sbjct: 307 DGLGP 311
Score = 37.4 bits (85), Expect = 0.016
Identities = 49/206 (23%), Positives = 76/206 (36%), Gaps = 27/206 (13%)
Query: 16 PRKTKMQEEEEVEPEPEMEAEVEPEPNPEEAETESESMPPEESFKEEEVAVADPSPQETK 75
P+ T +E+ + + E E P+E T+ E+ + E+ A A+P + K
Sbjct: 180 PKATVEEEDAKTASQEETGQRKECSTEPKEKATDEEAKAESQKAVVEDEAKAEPKEPDGK 239
Query: 76 EAAL-----TSTISLRAQGAEISEMNSPSRRVLTWLMK---GVEKVIPQPVHSITEDPAQ 127
E A + A+ AE +E SPS + K G VIP E P
Sbjct: 240 EEAKHGAKEEADAKEEAEDAEEAEPGSPSEEQEQDVEKEPEGGAGVIPSSPEEWPESPTG 299
Query: 128 ILGHGSTGDTG--CTDEPNEALEAQDTRPGLRLLLWLEQNLERVLPQPPKSSEVWRDEPA 185
+ ST G C + A ++ P ++ + P+ P S E P
Sbjct: 300 EGHNLSTDGLGPDCVASGQTSPSASESSP---------SDVPQSPPESPSSGEKKEKAPE 350
Query: 186 VATGAASDPAPPGRPQEMGPKLQARE 211
A P RP+ GP+ Q R+
Sbjct: 351 RRVSA------PARPR--GPRAQNRK 368
>gi|116517292 cut-like 2 [Homo sapiens]
Length = 1486
Score = 45.1 bits (105), Expect = 8e-05
Identities = 62/241 (25%), Positives = 84/241 (34%), Gaps = 49/241 (20%)
Query: 11 QPPGTPRKTKMQEEEEVEPEPEMEAEVEPEPNPEEAETESESMPPEESFK---------- 60
QP G R +E V PE E A E EP P E ++E E +
Sbjct: 818 QPNG--RAWPRGDEAPVPPEDEAAAGAEDEP-PRTGELKAEGATAEAGARLPYYPAYVPR 874
Query: 61 --EEEVAVADPSPQETKEAALTSTISLRAQGAEISEMNSPSRRVLTWLMKGVEKVIPQPV 118
+ V P E T+ L Q E N +R+ EKV+
Sbjct: 875 TLKPTVPPLTPEQYELYMYREVDTLELTRQVKEKLAKNGICQRIFG------EKVLG--- 925
Query: 119 HSITEDPAQILGHGSTGDTGCTDEPNEALEAQDTRPGLRLLLWLEQNLERVLPQPPKSSE 178
L GS D +P L + P +R+ LWL L + + Q P +S+
Sbjct: 926 ----------LSQGSVSDMLSRPKPWSKLTQKGREPFIRMQLWLSDQLGQAVGQQPGASQ 975
Query: 179 VWRDEPAVATGAASDPAPPGRPQEMGPKLQARETPSLPTPIPLQPKEEPKEAPAPEPQPG 238
EP S P+PP P E P+ ++E SL E KE PE +
Sbjct: 976 ASPTEP------RSSPSPPPSPTE--PEKSSQEPLSLSL-------ESSKENQQPEGRSS 1020
Query: 239 S 239
S
Sbjct: 1021 S 1021
Score = 35.0 bits (79), Expect = 0.080
Identities = 53/236 (22%), Positives = 82/236 (34%), Gaps = 50/236 (21%)
Query: 8 VLPQPPGTPRKTKMQEEEEVEPEPEMEAEVEPEPNPEEAET------ESESMPPEESFKE 61
+LP P T + E E + E+E + PEE T +++ +E +E
Sbjct: 1246 ILPPGHSHPDPTPQSPDSETEDQKPTVKELELQEGPEENSTPLTTQDKAQVRIKQEQMEE 1305
Query: 62 EEVAVADPSPQETKEAALTSTISLRAQGAEISEMNSPSRRVLTWLMKGVEKVIPQPVHSI 121
+ A PQ++ E + QG E P G+ KV P P
Sbjct: 1306 DAEEEAGSQPQDSGELD-------KGQGPPKEEHPDPPGN------DGLPKVAPGP---- 1348
Query: 122 TEDPAQILGHGSTGDTGCTDEPNEALEAQDTRPGLRLLLWLEQNLERVLPQP---PKSSE 178
+L GST D P + EA ER+ P P +SE
Sbjct: 1349 ------LLPGGSTPDCPSL-HPQQESEAG----------------ERLHPDPLSFKSASE 1385
Query: 179 VWRDEPAVATGAASDPAPPGRPQEMGPKLQARETPSLPTPIPLQPKEEPKEAPAPE 234
R V+ + S + PG + P + + P P+P P + P +P +
Sbjct: 1386 SSRCSLEVSLNSPSAASSPGLMMSVSP-VPSSSAPISPSPPGAPPAKVPSASPTAD 1440
>gi|58761548 tau tubulin kinase 1 [Homo sapiens]
Length = 1321
Score = 45.1 bits (105), Expect = 8e-05
Identities = 58/218 (26%), Positives = 79/218 (36%), Gaps = 42/218 (19%)
Query: 10 PQPPGTPRKTKMQEEEEVEPEPEMEAEVEPEPNPEEAETESESMPPEESFKEEEVAVADP 69
PQ P P + + +EE E E E E E E + EE E E E EE +EEE A A
Sbjct: 718 PQVPLAPVQPQANGKEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEAAAA-- 775
Query: 70 SPQETKEAALTSTISLRAQGAEISEMNSPSRRVLTWLMKGVEKVIPQPVHSITEDPAQIL 129
AL + R+ + S R +G P + +D +
Sbjct: 776 -------VALGEVLGPRSGSSSEGSERSTDRS-----QEGA------PSTLLADDQKESR 817
Query: 130 GHGSTGDTGCTDEPNEALEAQDTRPGLRLLLWLEQNLERVLPQPPKSSEVWRD---EPAV 186
G S D EP E + L V P K S V + +P +
Sbjct: 818 GRASMADGDL--EPEEG----------------SKTLVLVSPGDMKKSPVTAELAPDPDL 859
Query: 187 ATGAASDPAPPGRPQEMGPKLQARETPSLPTPIPLQPK 224
T AA P RPQ G +L E +L + + +PK
Sbjct: 860 GTLAALTPQHE-RPQPTGSQLDVSEPGTLSSVLKSEPK 896
Score = 30.0 bits (66), Expect = 2.6
Identities = 52/235 (22%), Positives = 81/235 (34%), Gaps = 31/235 (13%)
Query: 27 VEPEPEMEAEVEPEPNPEEAETESESMPPEESFKEEEVAVADPSPQETKEAALTSTISLR 86
+EP PE A + P + +P S EE ++PS + + + +
Sbjct: 1030 LEPSPEKVATISPRRHAMPGSRPRSRIPVLLS---EEDTGSEPSGSLSAKERWSKRARPQ 1086
Query: 87 AQGAEISEMNSPSRRVLTWLMKGVEKVIPQPVHSITEDPAQILGHGSTGDTGCTDE---- 142
A + M R+L L G + +E + G GS DT ++
Sbjct: 1087 QDLARLV-MEKRQGRLLLRLASGASSSSSEEQRRASET---LSGTGSEEDTPASEPAAAL 1142
Query: 143 PNEALEAQDTRPGLRLLLWLEQNLERVLPQPPKSSEVWRDEPAVATGAASDPAPPGRPQE 202
P ++ A TR + + L + QP S GAA P
Sbjct: 1143 PRKSGRAAATRSRIPRPIGLRMPMPVAAQQPASRSH----------GAA-----PALDTA 1187
Query: 203 MGPKLQARETPSLPTPIPLQPKEEPKEAPAPEPQPGSQAQTSSLPPTRDPARLVA 257
+ +LQ + P T L+PK+ P P +AQ + PP RL A
Sbjct: 1188 ITSRLQLQTPPGSATAADLRPKQPPGRGLGP-----GRAQAGARPPAPRSPRLPA 1237
>gi|116256464 hypothetical protein LOC343990 [Homo sapiens]
Length = 962
Score = 45.1 bits (105), Expect = 8e-05
Identities = 61/244 (25%), Positives = 82/244 (33%), Gaps = 56/244 (22%)
Query: 13 PGTPRKTKMQEEEEVEPEPEMEAEVEPEPNPEEAETESESMP----PEESFKEEEVAVA- 67
P TP + + + EP E P P P+ + + E+ P + K EEV A
Sbjct: 336 PATPELAEPESAPTLRVEPPSPPEGPPNPGPDGGKQDGEAPPAGPCAPATDKAEEVVCAP 395
Query: 68 --------------DPSPQETKEAALTSTISLRAQGAE--ISEMNSPSRRVLTWLMKGVE 111
D +P ET AA + S R G E + + P+ VL KG
Sbjct: 396 EDVASPFPTAIPEGDTTPPETDPAATSEAPSAR-DGPERSVPKEAEPTPPVLPDEEKGPP 454
Query: 112 KVIPQPVHSITEDPAQILGHGSTGDTGCTDEPNEALEAQDTRPGLRLLLWLEQNLERVLP 171
P+P +P + G EP T P P
Sbjct: 455 GPAPEPEREAETEP----------ERGAGTEPERIGTEPSTAPA---------------P 489
Query: 172 QPPKSSEVWRDEPAVAT-GAASDP---APPGRPQEMGPKLQARETPSLPTPIPLQPKEEP 227
PP + PA A+ G A+ P A P E GP E + P +PK E
Sbjct: 490 SPPAPKSCLKHRPAAASEGPAASPPLAAAESPPVEPGPGSLDAEAAA-----PERPKAER 544
Query: 228 KEAP 231
EAP
Sbjct: 545 AEAP 548
Score = 43.9 bits (102), Expect = 2e-04
Identities = 66/265 (24%), Positives = 91/265 (34%), Gaps = 40/265 (15%)
Query: 8 VLPQPPGTPRKTKMQEEEEVEPEPEMEAEVEPEPNPEEAETESESMPP-EESFKEEEVAV 66
VLP P + E E E EPE A EPE E T PP +S + A
Sbjct: 445 VLPDEEKGPPGPAPEPEREAETEPERGAGTEPERIGTEPSTAPAPSPPAPKSCLKHRPAA 504
Query: 67 ADPSPQETKEAALTSTISLR----AQGAEISEMNSPSRRVLTWLMKGVEKVIPQPVHSIT 122
A P + A + + + AE + P G E+ P+
Sbjct: 505 ASEGPAASPPLAAAESPPVEPGPGSLDAEAAAPERPKAERAEAPPAGAERAAPE--RKAE 562
Query: 123 EDPAQILGHGSTGDTGCTDEPNEALEAQDTRPGLRLLLWLEQNLERVLPQPP--KSSEVW 180
A++ G + C P RPG + + LER + P +S VW
Sbjct: 563 RGGAELRGAKKFSVSSCRARP---------RPG------VSRPLERASGRLPLARSGPVW 607
Query: 181 RDEPAVATGAASDPAP------PGRPQEMGPKLQARETPSLPTPIPLQPKEEPKEAPAP- 233
R E A+ P P P + E GP+ S P P++ P+EA A
Sbjct: 608 RSEAAL-DDLQGLPEPQHAKPGPRKLAERGPQDSGDRAAS-----PAGPRKSPQEAAAAP 661
Query: 234 ---EPQPGSQAQTSSLPPTRDPARL 255
EP P +Q S P +L
Sbjct: 662 GTREPCPAAQEPAPSEDRNPFPVKL 686
Score = 33.5 bits (75), Expect = 0.23
Identities = 53/242 (21%), Positives = 85/242 (35%), Gaps = 21/242 (8%)
Query: 16 PRKTKMQEEEEVEPEPEMEAEVEPEPNPEEAETESESM----PPEESFKEEEVAVADPSP 71
PR + + + + E+ + PEE E E + + P E ++ D P
Sbjct: 232 PRNQRSSKMRRLSSRAQSESLSDLTCTPEEEENEEKPLLEVSPEERPSSGQQDVAPDRGP 291
Query: 72 QETKEAALTSTISLRAQGAEISEMNSPSRRVLTWLMKGVEKV-------IPQPVHSIT-- 122
+ A L RA+ A + ++ + V + G + + +P + T
Sbjct: 292 EPGPPAPLPPPGGARARRARLQHSSALTASVEEGGVPGEDPSSRPATPELAEPESAPTLR 351
Query: 123 -EDPAQILGHGSTGDTGCTDEPNEALEAQDTRPGLRLLLWLEQNLERVLPQPPKSSEVWR 181
E P+ G + G G + EA A P + E V P +
Sbjct: 352 VEPPSPPEGPPNPGPDGGKQD-GEAPPAGPCAPATDKAEEVVCAPEDVASPFPTAIPEGD 410
Query: 182 DEPAVATGAASDPAPPGRPQEMGPKLQARETPSLPTPIPLQPKEEPKEAPAPEPQPGSQA 241
P AA+ AP R GP+ R P P P +E K P P P+P +A
Sbjct: 411 TTPPETDPAATSEAPSARD---GPE---RSVPKEAEPTPPVLPDEEKGPPGPAPEPEREA 464
Query: 242 QT 243
+T
Sbjct: 465 ET 466
>gi|14589876 embryonal Fyn-associated substrate isoform 2 [Homo
sapiens]
Length = 468
Score = 45.1 bits (105), Expect = 8e-05
Identities = 39/139 (28%), Positives = 52/139 (37%), Gaps = 28/139 (20%)
Query: 120 SITEDPAQILGHGSTG--DTGCTDEPNEALEAQDTRPGLRLLLWLEQNLERVLPQPPKSS 177
++ E P ++L G G D G D P EA + P+PP +
Sbjct: 138 NLYEAPEELLADGEGGGTDEGIYDVPLLGPEAPPS------------------PEPP-GA 178
Query: 178 EVWRDEPAVATGAASDPAPPGRPQ-EMGPKLQARETPSLPTPIPLQPKEEPKEAPAPEPQ 236
D+ +A A P PP RP+ L R P+LP P E P +P P P
Sbjct: 179 LASHDQDTLAQLLARSPPPPHRPRLPSAESLSRRPLPALPVP------EAPSPSPVPSPA 232
Query: 237 PGSQAQTSSLPPTRDPARL 255
PG + P P RL
Sbjct: 233 PGRKGSIQDRPLPPPPPRL 251
>gi|5031681 embryonal Fyn-associated substrate isoform 1 [Homo
sapiens]
Length = 561
Score = 45.1 bits (105), Expect = 8e-05
Identities = 39/139 (28%), Positives = 52/139 (37%), Gaps = 28/139 (20%)
Query: 120 SITEDPAQILGHGSTG--DTGCTDEPNEALEAQDTRPGLRLLLWLEQNLERVLPQPPKSS 177
++ E P ++L G G D G D P EA + P+PP +
Sbjct: 231 NLYEAPEELLADGEGGGTDEGIYDVPLLGPEAPPS------------------PEPP-GA 271
Query: 178 EVWRDEPAVATGAASDPAPPGRPQ-EMGPKLQARETPSLPTPIPLQPKEEPKEAPAPEPQ 236
D+ +A A P PP RP+ L R P+LP P E P +P P P
Sbjct: 272 LASHDQDTLAQLLARSPPPPHRPRLPSAESLSRRPLPALPVP------EAPSPSPVPSPA 325
Query: 237 PGSQAQTSSLPPTRDPARL 255
PG + P P RL
Sbjct: 326 PGRKGSIQDRPLPPPPPRL 344
>gi|157168329 formin 1 [Homo sapiens]
Length = 1196
Score = 44.7 bits (104), Expect = 1e-04
Identities = 31/107 (28%), Positives = 40/107 (37%), Gaps = 4/107 (3%)
Query: 150 QDTRPGLRLLLWLEQNLERVLPQPPKSSEVWRDEPAVATGAAS-DPAPPGRPQEMGPKLQ 208
+D L+ + + N ++ LP PP S P + +G S PAPP P GP L
Sbjct: 625 KDIHAALQPMEGMASNQQKALPPPPASIP---PPPPLPSGLGSLSPAPPMPPVSAGPPLP 681
Query: 209 ARETPSLPTPIPLQPKEEPKEAPAPEPQPGSQAQTSSLPPTRDPARL 255
P P P P P P P P + PP P L
Sbjct: 682 PPPPPPPPLPPPSSAGPPPPPPPPPLPNSPAPPNPGGPPPAPPPPGL 728
Score = 28.1 bits (61), Expect = 9.8
Identities = 21/69 (30%), Positives = 26/69 (37%), Gaps = 13/69 (18%)
Query: 170 LPQPPKSSEVWRDEPAVATGAASDPAPPGRPQEMGPKLQARETPSLPTPIPLQPKEEPKE 229
LP PP P + +++ P PP P + P A P P P P P
Sbjct: 680 LPPPPPPP------PPLPPPSSAGPPPPPPPPPL-PNSPAPPNPGGPPPAP------PPP 726
Query: 230 APAPEPQPG 238
AP P PG
Sbjct: 727 GLAPPPPPG 735
>gi|30089948 protein phosphatase 1E [Homo sapiens]
Length = 755
Score = 44.7 bits (104), Expect = 1e-04
Identities = 28/66 (42%), Positives = 33/66 (50%), Gaps = 10/66 (15%)
Query: 22 QEEEEVEPEPEMEAEVEPEPNPEEAETESESMPPEESFKEEEVAVA--------DPSPQE 73
+ E E EPEPE E E EPEP PE E E+ EE +E A DP P+E
Sbjct: 30 EPEPEPEPEPEPEPESEPEPEPELVEAEAAEASVEEPGEEAATVAATEEGDQEQDPEPEE 89
Query: 74 TKEAAL 79
EAA+
Sbjct: 90 --EAAV 93
Score = 30.8 bits (68), Expect = 1.5
Identities = 25/75 (33%), Positives = 34/75 (45%), Gaps = 8/75 (10%)
Query: 10 PQPPGTPRKTKMQEEEEVEPEPEM------EAEVEPEPNPEEAETESESMPPEESFKEEE 63
P+P P + + + E E EPEPE+ EA VE EP E A + +E E E
Sbjct: 31 PEPEPEP-EPEPEPESEPEPEPELVEAEAAEASVE-EPGEEAATVAATEEGDQEQDPEPE 88
Query: 64 VAVADPSPQETKEAA 78
A +E + AA
Sbjct: 89 EEAAVEGEEEEEGAA 103
Score = 30.4 bits (67), Expect = 2.0
Identities = 23/45 (51%), Positives = 24/45 (53%), Gaps = 4/45 (8%)
Query: 38 EPEPNPE-EAETESESMP-PEESFKEEEVAVADPSPQETKEAALT 80
EPEP PE E E E ES P PE E E A A S +E E A T
Sbjct: 30 EPEPEPEPEPEPEPESEPEPEPELVEAEAAEA--SVEEPGEEAAT 72
>gi|31324577 molecule interacting with Rab13 [Homo sapiens]
Length = 863
Score = 44.7 bits (104), Expect = 1e-04
Identities = 69/301 (22%), Positives = 103/301 (34%), Gaps = 39/301 (12%)
Query: 9 LPQPPGTPRKTKMQEEEEVEPEPEMEAEVEPEPNPEEAETESESMPPEESFKEEE----V 64
+P+P GTP+ ++ +P + EP+ P S PP + ++ E
Sbjct: 349 VPKPRGTPKPSEGTPAPRKDPPWITLVQAEPKKKPAPLPPSSSPGPPSQDSRQVENGGTE 408
Query: 65 AVADPSPQETKEAALTSTISLRAQGAEISEMNSPSRRVLTWLMKGVEKVIPQPVHSITED 124
VA PSP + E+ + + E +PS + T G + P+ +H
Sbjct: 409 EVAQPSPTASLESKPYNPFEEEEEDKEEEAPAAPS--LATSPALGHPESTPKSLHP---- 462
Query: 125 PAQILGHGSTGDTGCTDEPNEALEAQDTRP-GLRLLLWLEQNLERVLPQPPKSSEVWRDE 183
+G T + + A A P L P P S E E
Sbjct: 463 -----WYGITPTSSPKTKKRPAPRAPSASPLALHASRLSHSEPPSATPSPALSVESLSSE 517
Query: 184 PAVATGAASDPAPPGRPQEMG-PKLQARETPSLPTPIPLQPK-------EEPKEAPAPEP 235
A T A PP P+ P + A TP P + EP+ P+
Sbjct: 518 SASQTAGAELLEPPAVPKSSSEPAVHAPGTPGNPVSLSTNSSLASSGELVEPRVEQMPQA 577
Query: 236 QPGSQAQT--SSLPPTRDPARLVAWVLHRLEMALPQPVLHGKIGEQEP-DSPGICDVQTR 292
PG +T SS P P A P P+L +G++ P SPG Q +
Sbjct: 578 SPGLAPRTRGSSGPQPAKPC----------SGATPTPLL--LVGDRSPVPSPGSSSPQLQ 625
Query: 293 V 293
V
Sbjct: 626 V 626
Score = 38.9 bits (89), Expect = 0.006
Identities = 54/202 (26%), Positives = 76/202 (37%), Gaps = 28/202 (13%)
Query: 100 RRVLTWLMKGVEKVIPQPVHSITEDPAQILGHGSTGDT--GCTDEPNEALEAQDTRPGLR 157
RR + L+ G + P+ + + LG G+ T G +P + + Q
Sbjct: 192 RRCSSTLLPGAYENGPEEGTFVCAEHCARLGPGTRSGTRPGPFSQPKQQHQQQ------- 244
Query: 158 LLLWLEQNLERVLPQPPKSSEVWRDEPAVATGAASDPAPPGRPQ-----EMGPKLQARET 212
L ++ + V P SS PA A +P RPQ + KLQ +
Sbjct: 245 ----LAEDAKDVPGGGPSSSA-----PAGAEADGPKASPEARPQIPTKPRVPGKLQELAS 295
Query: 213 PSL--PTPIPLQPKEEPKEAPAPEPQPGSQAQTSSLPPTRDPARLVAWVLHRLEMALPQP 270
P PTP P + E AP P P+P S Q +L + LV LH L + P+
Sbjct: 296 PPAGRPTPAPRKASESTTPAP-PTPRPRSSLQQENLVEQAGSSSLVNGRLHELPVPKPRG 354
Query: 271 VLHGKIGEQEP--DSPGICDVQ 290
G P D P I VQ
Sbjct: 355 TPKPSEGTPAPRKDPPWITLVQ 376
Score = 32.3 bits (72), Expect = 0.52
Identities = 72/316 (22%), Positives = 108/316 (34%), Gaps = 71/316 (22%)
Query: 13 PGTPRKTKMQ-----EEEEVEPEPEMEAEVEP-EPNPEEAETESESMP------------ 54
PG P + Q EE +P P E +P P EE E + E P
Sbjct: 392 PGPPSQDSRQVENGGTEEVAQPSPTASLESKPYNPFEEEEEDKEEEAPAAPSLATSPALG 451
Query: 55 -PEESFKEEE--VAVADPSPQETKE-----AALTSTISLRAQGAEISEMNS--PSRRVLT 104
PE + K + S +TK+ A S ++L A SE S PS +
Sbjct: 452 HPESTPKSLHPWYGITPTSSPKTKKRPAPRAPSASPLALHASRLSHSEPPSATPSPALSV 511
Query: 105 WLMK--------GVEKVIPQPVHSITEDPA-----------QILGHGSTGDTGCTDEPNE 145
+ G E + P V + +PA + + S +G EP
Sbjct: 512 ESLSSESASQTAGAELLEPPAVPKSSSEPAVHAPGTPGNPVSLSTNSSLASSGELVEPRV 571
Query: 146 ALEAQDTRPGLRLLLWLEQNLERVLPQPPKSSEVWRDEPAVATGAASDPAPPGRPQEMGP 205
Q + PGL + PQP K P + G D +P P P
Sbjct: 572 EQMPQAS-PGLA-----PRTRGSSGPQPAKPCSGATPTPLLLVG---DRSPVPSPGSSSP 622
Query: 206 KLQARETPSLPTPIPLQPKEEP-KEAPAPEPQPGSQAQTSSLPPTRDPARLVAWVLHR-- 262
+LQ + + KE P P+P P ++ T P R PA + L +
Sbjct: 623 QLQVKSSC----------KENPFNRKPSPAASPATKKATKGSKPVRPPAPGHGFPLIKRK 672
Query: 263 --LEMALPQPVLHGKI 276
+ +P+ +HG++
Sbjct: 673 VQADQYIPEEDIHGEM 688
Score = 29.6 bits (65), Expect = 3.4
Identities = 39/164 (23%), Positives = 57/164 (34%), Gaps = 33/164 (20%)
Query: 116 QPVHSITEDPAQILGHGSTGDTGCTDEPNEALEAQDTRPGLRLLLWLEQNLE-------- 167
Q + ED + G G + E + + + RP + + L+
Sbjct: 240 QHQQQLAEDAKDVPGGGPSSSAPAGAEADGPKASPEARPQIPTKPRVPGKLQELASPPAG 299
Query: 168 RVLPQPPKSSEVWRDEPA------------VATGAASDPAPPGRPQEMG-PKLQARETPS 214
R P P K+SE P + A S GR E+ PK + PS
Sbjct: 300 RPTPAPRKASESTTPAPPTPRPRSSLQQENLVEQAGSSSLVNGRLHELPVPKPRGTPKPS 359
Query: 215 LPTPIPLQP-------KEEPKEAPAPEPQPGSQAQTSSLPPTRD 251
TP P + + EPK+ PAP P S PP++D
Sbjct: 360 EGTPAPRKDPPWITLVQAEPKKKPAPLPPSSSPG-----PPSQD 398
>gi|145386517 phostensin [Homo sapiens]
Length = 613
Score = 43.9 bits (102), Expect = 2e-04
Identities = 56/251 (22%), Positives = 86/251 (34%), Gaps = 45/251 (17%)
Query: 29 PEPEMEAEVEPEPNPEEAETESESMPPEESFKEEEVAVADPSPQETKEAALTSTISLRA- 87
PE + E +P E ES P E ++++ + A +++E+ S + L A
Sbjct: 200 PERSLRLAESREQSPRRKEVESRLSPGESAYQKLGLTEAHKWRPDSRESQEQSLVQLEAT 259
Query: 88 -----QGAEISEMNSPSRRVLTWLMKGVEKVIPQPVHSITED-PAQILGHGSTGDTGCTD 141
G E + + R W + GV P+ ++E + G+ S G
Sbjct: 260 EWRLRSGEERQDYSEECGRKEEWPVPGVA---PKETAELSETLTREAQGNSSAGVEAAEQ 316
Query: 142 EPNEALE-AQDTRPGLRLLL-------WLEQNLERVL--PQPPKSSEVWRDEPAVATG-- 189
P E E G + L W +++E P+PP+S+E + P V G
Sbjct: 317 RPVEDGERGMKPTEGWKWTLNSGKAREWTPRDIEAQTQKPEPPESAEKLLESPGVEAGEG 376
Query: 190 ---------------------AASDPAPPGRPQEMGPKLQARETPSL--PTPIPLQPKEE 226
+ P PP G + Q E L P P PL P
Sbjct: 377 EAEKEEAGAQGRPLRALQNCCSVPSPLPPEDAGTGGLRQQEEEAVELQPPPPAPLSPPPP 436
Query: 227 PKEAPAPEPQP 237
AP P P
Sbjct: 437 APTAPQPPGDP 447
Score = 28.1 bits (61), Expect = 9.8
Identities = 17/63 (26%), Positives = 30/63 (47%)
Query: 17 RKTKMQEEEEVEPEPEMEAEVEPEPNPEEAETESESMPPEESFKEEEVAVADPSPQETKE 76
R+ + Q++++ + E+ AE +P P S ++S K E SP+ET+E
Sbjct: 92 RQERQQQQQQQQRSEELLAERKPGPLEARERRPSPGEMRDQSPKGRESREERLSPRETRE 151
Query: 77 AAL 79
L
Sbjct: 152 RRL 154
>gi|199559805 phostensin [Homo sapiens]
Length = 613
Score = 43.9 bits (102), Expect = 2e-04
Identities = 56/251 (22%), Positives = 86/251 (34%), Gaps = 45/251 (17%)
Query: 29 PEPEMEAEVEPEPNPEEAETESESMPPEESFKEEEVAVADPSPQETKEAALTSTISLRA- 87
PE + E +P E ES P E ++++ + A +++E+ S + L A
Sbjct: 200 PERSLRLAESREQSPRRKEVESRLSPGESAYQKLGLTEAHKWRPDSRESQEQSLVQLEAT 259
Query: 88 -----QGAEISEMNSPSRRVLTWLMKGVEKVIPQPVHSITED-PAQILGHGSTGDTGCTD 141
G E + + R W + GV P+ ++E + G+ S G
Sbjct: 260 EWRLRSGEERQDYSEECGRKEEWPVPGVA---PKETAELSETLTREAQGNSSAGVEAAEQ 316
Query: 142 EPNEALE-AQDTRPGLRLLL-------WLEQNLERVL--PQPPKSSEVWRDEPAVATG-- 189
P E E G + L W +++E P+PP+S+E + P V G
Sbjct: 317 RPVEDGERGMKPTEGWKWTLNSGKAREWTPRDIEAQTQKPEPPESAEKLLESPGVEAGEG 376
Query: 190 ---------------------AASDPAPPGRPQEMGPKLQARETPSL--PTPIPLQPKEE 226
+ P PP G + Q E L P P PL P
Sbjct: 377 EAEKEEAGAQGRPLRALQNCCSVPSPLPPEDAGTGGLRQQEEEAVELQPPPPAPLSPPPP 436
Query: 227 PKEAPAPEPQP 237
AP P P
Sbjct: 437 APTAPQPPGDP 447
Score = 28.1 bits (61), Expect = 9.8
Identities = 17/63 (26%), Positives = 30/63 (47%)
Query: 17 RKTKMQEEEEVEPEPEMEAEVEPEPNPEEAETESESMPPEESFKEEEVAVADPSPQETKE 76
R+ + Q++++ + E+ AE +P P S ++S K E SP+ET+E
Sbjct: 92 RQERQQQQQQQQRSEELLAERKPGPLEARERRPSPGEMRDQSPKGRESREERLSPRETRE 151
Query: 77 AAL 79
L
Sbjct: 152 RRL 154
>gi|153792074 proline rich 12 [Homo sapiens]
Length = 2036
Score = 43.1 bits (100), Expect = 3e-04
Identities = 61/245 (24%), Positives = 85/245 (34%), Gaps = 30/245 (12%)
Query: 12 PPGTPRKTKMQEEEEVEPEPEMEAEVEPEPNPEEAETESESMPPEESFKEEEVAVADPSP 71
PP P + ++P+P V P P P A ++ ES E + + PSP
Sbjct: 1314 PPSVPARG-------LQPQPPATPAV-PHPPPSGAFGLGGALEAAES---EGLGLGCPSP 1362
Query: 72 QETKEAALTSTISLRAQGAEISEMNSPSRRVLTWLMKGVEKVIPQPVHSITEDPAQILGH 131
+ + L + + E + R L ++ I + ++ + P
Sbjct: 1363 CKRLDEELKRNLETLPSFSSDEEDSVAKNRDL-------QESISSAISALDDPPL----- 1410
Query: 132 GSTGDTGCTDEPNEALEAQDTRPGLRLLLWLEQNLERVLPQPPKSSEVWRDEPAVATGAA 191
DT D P A A PG L L P+PP E P A
Sbjct: 1411 AGPKDTSTPDGPPLAPAA--AVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQ 1468
Query: 192 SDPAPPGRPQEMG---PKLQARETPSLPTPIPLQPKEEPKEAPAPEPQPGSQAQTSSLPP 248
P PP P + P TPS P P PL P P P+P P P A + PP
Sbjct: 1469 PQPPPPPPPPQPALPSPPPLVAPTPSSPPPPPLPPPPPPA-MPSPPPPPPPAAAPLAAPP 1527
Query: 249 TRDPA 253
+PA
Sbjct: 1528 -EEPA 1531
Score = 36.2 bits (82), Expect = 0.036
Identities = 19/64 (29%), Positives = 23/64 (35%)
Query: 171 PQPPKSSEVWRDEPAVATGAASDPAPPGRPQEMGPKLQARETPSLPTPIPLQPKEEPKEA 230
P PP P + S P PP P P + + P P PL E A
Sbjct: 1473 PPPPPPQPALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSPPPPPPPAAAPLAAPPEEPAA 1532
Query: 231 PAPE 234
P+PE
Sbjct: 1533 PSPE 1536
Score = 33.9 bits (76), Expect = 0.18
Identities = 23/80 (28%), Positives = 29/80 (36%), Gaps = 9/80 (11%)
Query: 171 PQPPKSSEVWRDEPAVATGAASDPAPPGRPQEMGPKLQARETPSLPTPIPLQPKEEPKEA 230
P PP + P VA +S P PP P P++P+P P P A
Sbjct: 1474 PPPPPQPALPSPPPLVAPTPSSPPPPPLPPPP---------PPAMPSPPPPPPPAAAPLA 1524
Query: 231 PAPEPQPGSQAQTSSLPPTR 250
PE + LP TR
Sbjct: 1525 APPEEPAAPSPEDPELPDTR 1544
Score = 30.0 bits (66), Expect = 2.6
Identities = 26/103 (25%), Positives = 39/103 (37%), Gaps = 6/103 (5%)
Query: 10 PQPPGTPRKTKMQEEEEVEPEPEMEAEVEPEP----NPEEAETESESMPPEESFKEEEVA 65
P P TP KT ++ E PE M PE P E E E E + E E A
Sbjct: 1700 PPKPETPEKTTSEKPPEQTPETAMPEPPAPEKPSLLRPVEKEKEKEKVTRGERPLRGERA 1759
Query: 66 VADPSPQETKEAALTSTISLRAQGAEISEMNS--PSRRVLTWL 106
+ + + A + R A +++ + P ++ WL
Sbjct: 1760 TSGRQTRPERSLATGQPATSRLPKARPTKVKAEPPPKKRKKWL 1802
Score = 29.6 bits (65), Expect = 3.4
Identities = 26/86 (30%), Positives = 33/86 (38%), Gaps = 15/86 (17%)
Query: 183 EPAVATGAASDPAPPGRPQEMGP-KLQARETPSLPTPIPLQPKEEPKEAPAP-------- 233
EPA GA P PP P P +L+A P P+ P+E+ P
Sbjct: 825 EPATRDGAPQPPPPPPPPPPPMPLQLEAHLRSHGLEPAAPSPRLRPEESLDPPGAMQELL 884
Query: 234 ---EPQPGSQAQTSSLPPT---RDPA 253
EP P + T PP +DPA
Sbjct: 885 GALEPLPPAPGDTGVGPPNSEGKDPA 910
Score = 28.5 bits (62), Expect = 7.5
Identities = 19/69 (27%), Positives = 28/69 (40%), Gaps = 1/69 (1%)
Query: 173 PPKSSEVWRDEPAVATGAASDPAPPGRPQEMGPKLQARETPSLPTPIPLQPKEEPKEAPA 232
PP + +P S+ P P+ P+ A E PSL P+ + KE+ K
Sbjct: 1692 PPPKAPAPPPKPETPEKTTSEKPPEQTPETAMPEPPAPEKPSLLRPVE-KEKEKEKVTRG 1750
Query: 233 PEPQPGSQA 241
P G +A
Sbjct: 1751 ERPLRGERA 1759
Score = 28.1 bits (61), Expect = 9.8
Identities = 16/45 (35%), Positives = 23/45 (51%), Gaps = 12/45 (26%)
Query: 227 PKEAPAPEPQPGS-QAQTSSLPPTRDPARLVAWVLHRLEMALPQP 270
P +APAP P+P + + TS PP + P E A+P+P
Sbjct: 1693 PPKAPAPPPKPETPEKTTSEKPPEQTP-----------ETAMPEP 1726
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 42.7 bits (99), Expect = 4e-04
Identities = 60/268 (22%), Positives = 111/268 (41%), Gaps = 42/268 (15%)
Query: 5 VQRVLPQPPGTPRKTKMQEEEEV--EPEPEMEAEVEPEP-----------NPEEAETESE 51
V + PQP T K ++++ PEP+ + +P P EA++ S+
Sbjct: 672 VSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSK 731
Query: 52 SMPPEE---SFKEEEVAVADPSPQETKEAALTSTISLRAQGAEISEMNSPSRRVLTWLMK 108
PP+E ++++ VAD P++ K + T L + + ++ + PS +V + +
Sbjct: 732 PAPPKEPSVPSEQDKAPVADDKPKQPK--MVKPTTDLVSSSSATTKPDIPSSKVQS---Q 786
Query: 109 GVEKVIPQPVHSITEDPAQILGHGSTGD-TGCTDEPNEALEAQDTR----PGLRLLLWLE 163
EK P P+ + + P+Q TG+ D A D++ PG E
Sbjct: 787 AEEKTTP-PLKTDSAKPSQ--SFPPTGEKVSPFDSKAIPRPASDSKIISHPGPS----SE 839
Query: 164 QNLERVLPQPPKSSEVWRDEPAVATGAASDPAPPGRPQEMGPKLQARETPSLPTPIPLQP 223
++ + K E + + ++ + P P G P GP+ A +T P P +P
Sbjct: 840 SKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSP-KP 898
Query: 224 KEEPKE--------APAPEPQPGSQAQT 243
+E+ + AP+ QP + +T
Sbjct: 899 QEQSRRFSLNLGSITDAPKSQPTTPQET 926
Score = 41.2 bits (95), Expect = 0.001
Identities = 61/258 (23%), Positives = 90/258 (34%), Gaps = 37/258 (14%)
Query: 10 PQPPGTPRKTKMQEEEEVEPEPEMEAEVEPEPNPEEAETESESMPPEESFKEEEVAVADP 69
PQ PG+ K Q+ +P P+ +P P + + PP + + + P
Sbjct: 491 PQQPGSA-KPPSQQPGSTKPPPQQPGPAKPSP-----QQPGSTKPPSQQPGSAKPSAQQP 544
Query: 70 SPQETKEAALTSTISLRAQGAEISEMN-SPSRRVLTWLMKGVEKVIPQPVHSITEDPAQI 128
SP + T +S G + SPS + +G+ K I P+ + TE +
Sbjct: 545 SPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPP--SQGLPKTI-CPLCNTTE----L 597
Query: 129 LGH--GSTGDTGCTDEPNEALEAQDTRPGLRLL-----LWLEQNLERVL-----PQPPKS 176
L H CT+ P L L L ++R L P P
Sbjct: 598 LLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSP 657
Query: 177 SEVWRDEPAVATGAASDPAPPGRPQEMGPKLQARETPSLPTPIPLQPKEEPKEAPAPEPQ 236
+ P T A S +P +PQ+ PK A L EPK+ P Q
Sbjct: 658 QPKLKTAPVTTTSAVSKSSP--QPQQTSPKKDAAPKQD------LSKAPEPKKPPPLVKQ 709
Query: 237 P---GSQAQTSSLPPTRD 251
P GS + + PP D
Sbjct: 710 PTLHGSPSAKAKQPPEAD 727
Score = 35.4 bits (80), Expect = 0.061
Identities = 56/245 (22%), Positives = 86/245 (35%), Gaps = 29/245 (11%)
Query: 9 LPQPPGTPRKTKMQEEEEVEPEPEMEAEVEPEPNPEEAETESESMPPEESFKEEEVAVAD 68
L Q PGT K +Q +P + +P +E S P ++ +
Sbjct: 342 LAQQPGTV-KPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKT 400
Query: 69 PSPQETKEAALTSTISLRAQGAEISEMNSPSRRVLTWLMKGVEKV-IPQPVHSITEDPAQ 127
P+ Q T + A+ + SP++ G K + QP + PAQ
Sbjct: 401 PAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKA------PGPTKTPVQQPGPG--KIPAQ 452
Query: 128 ILGHGSTG--DTGCTDEPNEALEAQDTRPGLRLLLWLEQNLERVLPQPPKSSEVWRDEPA 185
G G T TG T P++ PG + + PQ P S++ P+
Sbjct: 453 QAGPGKTSAQQTGPTKPPSQL-------PGPAKPPPQQPGPAKPPPQQPGSAK----PPS 501
Query: 186 VATGAASDPAPPGRPQEMGPKLQARETPSLPTPIPLQPKEEPKEAPAPEP-QPGSQAQTS 244
G+ P PQ+ GP + + P P QP A P P +P +Q T
Sbjct: 502 QQPGSTKPP-----PQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTK 556
Query: 245 SLPPT 249
+ T
Sbjct: 557 PVSQT 561
Score = 35.0 bits (79), Expect = 0.080
Identities = 59/251 (23%), Positives = 96/251 (38%), Gaps = 56/251 (22%)
Query: 11 QPPGTPRKTKMQEEEEVEPEPEMEAEVEPEPNPEEAETESESMPPEESFKEEEVAVADPS 70
Q GTP+ Q+ E+++ +P + P + +T+ +P + D S
Sbjct: 231 QQDGTPKSISSQQPEKIKSQPPGTGKPIQGPT-QTPQTDHAKLPLQR----------DAS 279
Query: 71 PQETKEAALTSTISLRAQGAEISEMNSPSRRVLTWLMKGVEKVIPQPVHSITEDPAQILG 130
+TK+A + S++ + SPS+ I QP + PAQ G
Sbjct: 280 RPQTKQADIVRGESVKPS------LPSPSK-----------PPIQQPTPG--KPPAQQPG 320
Query: 131 HGSTGDTGCTDEPNEALEAQDTRPGLRLLLWLEQNLERVLP--QPPKSSEVWRDEPAVAT 188
H + G P A + T+P L Q V P QPP +++ PA
Sbjct: 321 HEKS-QPGPAKPP--AQPSGLTKP-------LAQQPGTVKPPVQPPGTTK----PPAQPL 366
Query: 189 GAASDPAPPGRPQEMGPKLQARETP-----SLPTPIPLQPKEEPKEAPAPEPQPGSQAQT 243
G A PA Q+ G + + E P + P + P ++P A P Q G+
Sbjct: 367 GPAKPPA-----QQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPL 421
Query: 244 SSLPPTRDPAR 254
+ P + PA+
Sbjct: 422 AQQPGLQSPAK 432
Score = 29.3 bits (64), Expect = 4.4
Identities = 23/92 (25%), Positives = 42/92 (45%), Gaps = 2/92 (2%)
Query: 8 VLPQPPGTPRKTKMQEEEEVEPEPEMEAEVEPEPNPEEAETESESMPPEESFKEEEVAVA 67
+LP + + +++EEEE+ E E + E+E + ++ + + + E
Sbjct: 1766 LLPTIEDSSEEEELREEEELLKEQEKQREIEQQQRKSSSKKSKKDKDELRAQRRRERPKT 1825
Query: 68 DPSPQETKEAALTSTISLRAQGAEISEMNSPS 99
PS E A + T LR Q AE+ E++ S
Sbjct: 1826 PPSNLSPIEDA-SPTEELR-QAAEMEELHRSS 1855
Score = 28.5 bits (62), Expect = 7.5
Identities = 19/64 (29%), Positives = 25/64 (39%), Gaps = 1/64 (1%)
Query: 184 PAVATGAASDPAPPGRPQEMGPKLQARETPSLPTPIPLQPKEEPKEAPAPEPQPGSQAQT 243
P+ + +S PA P RP L P P P P P P P P P + +
Sbjct: 2377 PSGSPSVSSLPAKP-RPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKP 2435
Query: 244 SSLP 247
+ LP
Sbjct: 2436 TILP 2439
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 42.7 bits (99), Expect = 4e-04
Identities = 60/268 (22%), Positives = 111/268 (41%), Gaps = 42/268 (15%)
Query: 5 VQRVLPQPPGTPRKTKMQEEEEV--EPEPEMEAEVEPEP-----------NPEEAETESE 51
V + PQP T K ++++ PEP+ + +P P EA++ S+
Sbjct: 672 VSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSK 731
Query: 52 SMPPEE---SFKEEEVAVADPSPQETKEAALTSTISLRAQGAEISEMNSPSRRVLTWLMK 108
PP+E ++++ VAD P++ K + T L + + ++ + PS +V + +
Sbjct: 732 PAPPKEPSVPSEQDKAPVADDKPKQPK--MVKPTTDLVSSSSATTKPDIPSSKVQS---Q 786
Query: 109 GVEKVIPQPVHSITEDPAQILGHGSTGD-TGCTDEPNEALEAQDTR----PGLRLLLWLE 163
EK P P+ + + P+Q TG+ D A D++ PG E
Sbjct: 787 AEEKTTP-PLKTDSAKPSQ--SFPPTGEKVSPFDSKAIPRPASDSKIISHPGPS----SE 839
Query: 164 QNLERVLPQPPKSSEVWRDEPAVATGAASDPAPPGRPQEMGPKLQARETPSLPTPIPLQP 223
++ + K E + + ++ + P P G P GP+ A +T P P +P
Sbjct: 840 SKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSP-KP 898
Query: 224 KEEPKE--------APAPEPQPGSQAQT 243
+E+ + AP+ QP + +T
Sbjct: 899 QEQSRRFSLNLGSITDAPKSQPTTPQET 926
Score = 41.2 bits (95), Expect = 0.001
Identities = 61/258 (23%), Positives = 90/258 (34%), Gaps = 37/258 (14%)
Query: 10 PQPPGTPRKTKMQEEEEVEPEPEMEAEVEPEPNPEEAETESESMPPEESFKEEEVAVADP 69
PQ PG+ K Q+ +P P+ +P P + + PP + + + P
Sbjct: 491 PQQPGSA-KPPSQQPGSTKPPPQQPGPAKPSP-----QQPGSTKPPSQQPGSAKPSAQQP 544
Query: 70 SPQETKEAALTSTISLRAQGAEISEMN-SPSRRVLTWLMKGVEKVIPQPVHSITEDPAQI 128
SP + T +S G + SPS + +G+ K I P+ + TE +
Sbjct: 545 SPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPP--SQGLPKTI-CPLCNTTE----L 597
Query: 129 LGH--GSTGDTGCTDEPNEALEAQDTRPGLRLL-----LWLEQNLERVL-----PQPPKS 176
L H CT+ P L L L ++R L P P
Sbjct: 598 LLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSP 657
Query: 177 SEVWRDEPAVATGAASDPAPPGRPQEMGPKLQARETPSLPTPIPLQPKEEPKEAPAPEPQ 236
+ P T A S +P +PQ+ PK A L EPK+ P Q
Sbjct: 658 QPKLKTAPVTTTSAVSKSSP--QPQQTSPKKDAAPKQD------LSKAPEPKKPPPLVKQ 709
Query: 237 P---GSQAQTSSLPPTRD 251
P GS + + PP D
Sbjct: 710 PTLHGSPSAKAKQPPEAD 727
Score = 35.4 bits (80), Expect = 0.061
Identities = 56/245 (22%), Positives = 86/245 (35%), Gaps = 29/245 (11%)
Query: 9 LPQPPGTPRKTKMQEEEEVEPEPEMEAEVEPEPNPEEAETESESMPPEESFKEEEVAVAD 68
L Q PGT K +Q +P + +P +E S P ++ +
Sbjct: 342 LAQQPGTV-KPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKT 400
Query: 69 PSPQETKEAALTSTISLRAQGAEISEMNSPSRRVLTWLMKGVEKV-IPQPVHSITEDPAQ 127
P+ Q T + A+ + SP++ G K + QP + PAQ
Sbjct: 401 PAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKA------PGPTKTPVQQPGPG--KIPAQ 452
Query: 128 ILGHGSTG--DTGCTDEPNEALEAQDTRPGLRLLLWLEQNLERVLPQPPKSSEVWRDEPA 185
G G T TG T P++ PG + + PQ P S++ P+
Sbjct: 453 QAGPGKTSAQQTGPTKPPSQL-------PGPAKPPPQQPGPAKPPPQQPGSAK----PPS 501
Query: 186 VATGAASDPAPPGRPQEMGPKLQARETPSLPTPIPLQPKEEPKEAPAPEP-QPGSQAQTS 244
G+ P PQ+ GP + + P P QP A P P +P +Q T
Sbjct: 502 QQPGSTKPP-----PQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTK 556
Query: 245 SLPPT 249
+ T
Sbjct: 557 PVSQT 561
Score = 35.0 bits (79), Expect = 0.080
Identities = 59/251 (23%), Positives = 96/251 (38%), Gaps = 56/251 (22%)
Query: 11 QPPGTPRKTKMQEEEEVEPEPEMEAEVEPEPNPEEAETESESMPPEESFKEEEVAVADPS 70
Q GTP+ Q+ E+++ +P + P + +T+ +P + D S
Sbjct: 231 QQDGTPKSISSQQPEKIKSQPPGTGKPIQGPT-QTPQTDHAKLPLQR----------DAS 279
Query: 71 PQETKEAALTSTISLRAQGAEISEMNSPSRRVLTWLMKGVEKVIPQPVHSITEDPAQILG 130
+TK+A + S++ + SPS+ I QP + PAQ G
Sbjct: 280 RPQTKQADIVRGESVKPS------LPSPSK-----------PPIQQPTPG--KPPAQQPG 320
Query: 131 HGSTGDTGCTDEPNEALEAQDTRPGLRLLLWLEQNLERVLP--QPPKSSEVWRDEPAVAT 188
H + G P A + T+P L Q V P QPP +++ PA
Sbjct: 321 HEKS-QPGPAKPP--AQPSGLTKP-------LAQQPGTVKPPVQPPGTTK----PPAQPL 366
Query: 189 GAASDPAPPGRPQEMGPKLQARETP-----SLPTPIPLQPKEEPKEAPAPEPQPGSQAQT 243
G A PA Q+ G + + E P + P + P ++P A P Q G+
Sbjct: 367 GPAKPPA-----QQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPL 421
Query: 244 SSLPPTRDPAR 254
+ P + PA+
Sbjct: 422 AQQPGLQSPAK 432
Score = 29.3 bits (64), Expect = 4.4
Identities = 23/92 (25%), Positives = 42/92 (45%), Gaps = 2/92 (2%)
Query: 8 VLPQPPGTPRKTKMQEEEEVEPEPEMEAEVEPEPNPEEAETESESMPPEESFKEEEVAVA 67
+LP + + +++EEEE+ E E + E+E + ++ + + + E
Sbjct: 1766 LLPTIEDSSEEEELREEEELLKEQEKQREIEQQQRKSSSKKSKKDKDELRAQRRRERPKT 1825
Query: 68 DPSPQETKEAALTSTISLRAQGAEISEMNSPS 99
PS E A + T LR Q AE+ E++ S
Sbjct: 1826 PPSNLSPIEDA-SPTEELR-QAAEMEELHRSS 1855
Score = 28.5 bits (62), Expect = 7.5
Identities = 19/64 (29%), Positives = 25/64 (39%), Gaps = 1/64 (1%)
Query: 184 PAVATGAASDPAPPGRPQEMGPKLQARETPSLPTPIPLQPKEEPKEAPAPEPQPGSQAQT 243
P+ + +S PA P RP L P P P P P P P P P + +
Sbjct: 2377 PSGSPSVSSLPAKP-RPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKP 2435
Query: 244 SSLP 247
+ LP
Sbjct: 2436 TILP 2439
>gi|23957680 ral guanine nucleotide dissociation stimulator-like 4
[Homo sapiens]
Length = 473
Score = 42.4 bits (98), Expect = 5e-04
Identities = 34/103 (33%), Positives = 46/103 (44%), Gaps = 9/103 (8%)
Query: 160 LWLEQNLERVLPQP--PKSSEVWRDEPAVATGA------ASDPAPPGRPQEMGPKLQARE 211
L LE + E VL Q P+ +E D+PA G A +PAPP ++GP L+
Sbjct: 100 LGLEDHQEIVLGQLVLPEPNEAKPDDPAPRPGQHALTMPALEPAPP-LLADLGPALEPES 158
Query: 212 TPSLPTPIPLQPKEEPKEAPAPEPQPGSQAQTSSLPPTRDPAR 254
+L P L P AP P PG+ + S P + P R
Sbjct: 159 PAALGPPGYLHSAPGPAPAPGEGPPPGTVLEPQSAPESSCPCR 201
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.307 0.128 0.378
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,972,045
Number of Sequences: 37866
Number of extensions: 1124974
Number of successful extensions: 15077
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 587
Number of HSP's successfully gapped in prelim test: 1004
Number of HSP's that attempted gapping in prelim test: 7569
Number of HSP's gapped (non-prelim): 6271
length of query: 299
length of database: 18,247,518
effective HSP length: 102
effective length of query: 197
effective length of database: 14,385,186
effective search space: 2833881642
effective search space used: 2833881642
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (22.0 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.