Guide to the Human Genome
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Search of human proteins with 207113147

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|207113147 heat shock transcription factor 2 isoform b [Homo
sapiens]
         (518 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|207113147 heat shock transcription factor 2 isoform b [Homo s...  1016   0.0  
gi|4758568 heat shock transcription factor 2 isoform a [Homo sap...  1004   0.0  
gi|5031767 heat shock transcription factor 1 [Homo sapiens]           282   6e-76
gi|100913209 heat shock transcription factor 4 isoform b [Homo s...   193   4e-49
gi|100913211 heat shock transcription factor 4 isoform a [Homo s...   193   4e-49
gi|122937277 heat shock transcription factor family member 5 [Ho...    67   4e-11
gi|50312655 heat shock transcription factor, Y-linked 1 isoform ...    59   8e-09
gi|32526913 heat shock transcription factor, Y linked 2 isoform ...    59   8e-09
gi|239752444 PREDICTED: similar to heat shock transcription fact...    59   1e-08
gi|239746964 PREDICTED: similar to heat shock transcription fact...    59   1e-08
gi|169216697 PREDICTED: heat shock transcription factor family, ...    51   2e-06
gi|24211017 heat shock transcription factor, Y-linked 1 isoform ...    51   2e-06
gi|7706603 heat shock transcription factor family, X linked 1 [H...    51   2e-06
gi|50312659 heat shock transcription factor, Y linked 2 isoform ...    51   2e-06
gi|42734430 polymerase I and transcript release factor [Homo sap...    42   0.001
gi|56550047 uveal autoantigen with coiled-coil domains and ankyr...    42   0.001
gi|59850762 uveal autoantigen with coiled-coil domains and ankyr...    42   0.001
gi|150010552 FK506 binding protein 15, 133kDa [Homo sapiens]           41   0.003
gi|149363642 coiled-coil domain containing 144A [Homo sapiens]         41   0.003
gi|11968023 zinc finger protein 106 homolog [Homo sapiens]             40   0.005
gi|41393608 reticulon 3 isoform b [Homo sapiens]                       40   0.007
gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H...    40   0.007
gi|239747446 PREDICTED: similar to Neuroblastoma breakpoint fami...    39   0.009
gi|154354990 ankyrin repeat domain 26 [Homo sapiens]                   39   0.009
gi|16445033 ACRC protein [Homo sapiens]                                39   0.015
gi|239741304 PREDICTED: similar to Neuroblastoma breakpoint fami...    38   0.020
gi|239741281 PREDICTED: Neuroblastoma breakpoint family member 6...    38   0.020
gi|112734867 retinitis pigmentosa GTPase regulator interacting p...    38   0.020
gi|87299628 biorientation of chromosomes in cell division 1-like...    38   0.025
gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo...    38   0.025

>gi|207113147 heat shock transcription factor 2 isoform b [Homo
           sapiens]
          Length = 518

 Score = 1016 bits (2626), Expect = 0.0
 Identities = 518/518 (100%), Positives = 518/518 (100%)

Query: 1   MKQSSNVPAFLSKLWTLVEETHTNEFITWSQNGQSFLVLDEQRFAKEILPKYFKHNNMAS 60
           MKQSSNVPAFLSKLWTLVEETHTNEFITWSQNGQSFLVLDEQRFAKEILPKYFKHNNMAS
Sbjct: 1   MKQSSNVPAFLSKLWTLVEETHTNEFITWSQNGQSFLVLDEQRFAKEILPKYFKHNNMAS 60

Query: 61  FVRQLNMYGFRKVVHIDSGIVKQERDGPVEFQHPYFKQGQDDLLENIKRKVSSSKPEENK 120
           FVRQLNMYGFRKVVHIDSGIVKQERDGPVEFQHPYFKQGQDDLLENIKRKVSSSKPEENK
Sbjct: 61  FVRQLNMYGFRKVVHIDSGIVKQERDGPVEFQHPYFKQGQDDLLENIKRKVSSSKPEENK 120

Query: 121 IRQEDLTKIISSAQKVQIKQETIESRLSELKSENESLWKEVSELRAKHAQQQQVIRKIVQ 180
           IRQEDLTKIISSAQKVQIKQETIESRLSELKSENESLWKEVSELRAKHAQQQQVIRKIVQ
Sbjct: 121 IRQEDLTKIISSAQKVQIKQETIESRLSELKSENESLWKEVSELRAKHAQQQQVIRKIVQ 180

Query: 181 FIVTLVQNNQLVSLKRKRPLLLNTNGAQKKNLFQHIVKEPTDNHHHKVPHSRTEGLKPRE 240
           FIVTLVQNNQLVSLKRKRPLLLNTNGAQKKNLFQHIVKEPTDNHHHKVPHSRTEGLKPRE
Sbjct: 181 FIVTLVQNNQLVSLKRKRPLLLNTNGAQKKNLFQHIVKEPTDNHHHKVPHSRTEGLKPRE 240

Query: 241 RISDDIIIYDVTDDNADEENIPVIPETNEDVISDPSNCSQYPDIVIVEDDNEDEYAPVIQ 300
           RISDDIIIYDVTDDNADEENIPVIPETNEDVISDPSNCSQYPDIVIVEDDNEDEYAPVIQ
Sbjct: 241 RISDDIIIYDVTDDNADEENIPVIPETNEDVISDPSNCSQYPDIVIVEDDNEDEYAPVIQ 300

Query: 301 SGEQNEPARESLSSGSDGSSPLMSSAVQLNGSSSLTSEDPVTMMDSILNDNINLLGKVEL 360
           SGEQNEPARESLSSGSDGSSPLMSSAVQLNGSSSLTSEDPVTMMDSILNDNINLLGKVEL
Sbjct: 301 SGEQNEPARESLSSGSDGSSPLMSSAVQLNGSSSLTSEDPVTMMDSILNDNINLLGKVEL 360

Query: 361 LDYLDSIDCSLEDFQAMLSGRQFSIDPDLLVDSENKGLETTKNNVVQPVSEEGRKSKSKP 420
           LDYLDSIDCSLEDFQAMLSGRQFSIDPDLLVDSENKGLETTKNNVVQPVSEEGRKSKSKP
Sbjct: 361 LDYLDSIDCSLEDFQAMLSGRQFSIDPDLLVDSENKGLETTKNNVVQPVSEEGRKSKSKP 420

Query: 421 DKQLIQYTAFPLLAFLDGNPASSVEQASTTASSEVLSSVDKPIEVDELLDSSLDPEPTQS 480
           DKQLIQYTAFPLLAFLDGNPASSVEQASTTASSEVLSSVDKPIEVDELLDSSLDPEPTQS
Sbjct: 421 DKQLIQYTAFPLLAFLDGNPASSVEQASTTASSEVLSSVDKPIEVDELLDSSLDPEPTQS 480

Query: 481 KLVRLEPLTEAEASEATLFYLCELAPAPLDSDMPLLDS 518
           KLVRLEPLTEAEASEATLFYLCELAPAPLDSDMPLLDS
Sbjct: 481 KLVRLEPLTEAEASEATLFYLCELAPAPLDSDMPLLDS 518


>gi|4758568 heat shock transcription factor 2 isoform a [Homo
           sapiens]
          Length = 536

 Score = 1004 bits (2597), Expect = 0.0
 Identities = 518/536 (96%), Positives = 518/536 (96%), Gaps = 18/536 (3%)

Query: 1   MKQSSNVPAFLSKLWTLVEETHTNEFITWSQNGQSFLVLDEQRFAKEILPKYFKHNNMAS 60
           MKQSSNVPAFLSKLWTLVEETHTNEFITWSQNGQSFLVLDEQRFAKEILPKYFKHNNMAS
Sbjct: 1   MKQSSNVPAFLSKLWTLVEETHTNEFITWSQNGQSFLVLDEQRFAKEILPKYFKHNNMAS 60

Query: 61  FVRQLNMYGFRKVVHIDSGIVKQERDGPVEFQHPYFKQGQDDLLENIKRKVSSSKPEENK 120
           FVRQLNMYGFRKVVHIDSGIVKQERDGPVEFQHPYFKQGQDDLLENIKRKVSSSKPEENK
Sbjct: 61  FVRQLNMYGFRKVVHIDSGIVKQERDGPVEFQHPYFKQGQDDLLENIKRKVSSSKPEENK 120

Query: 121 IRQEDLTKIISSAQKVQIKQETIESRLSELKSENESLWKEVSELRAKHAQQQQVIRKIVQ 180
           IRQEDLTKIISSAQKVQIKQETIESRLSELKSENESLWKEVSELRAKHAQQQQVIRKIVQ
Sbjct: 121 IRQEDLTKIISSAQKVQIKQETIESRLSELKSENESLWKEVSELRAKHAQQQQVIRKIVQ 180

Query: 181 FIVTLVQNNQLVSLKRKRPLLLNTNGAQKKNLFQHIVKEPTDNHHHKVPHSRTEGLKPRE 240
           FIVTLVQNNQLVSLKRKRPLLLNTNGAQKKNLFQHIVKEPTDNHHHKVPHSRTEGLKPRE
Sbjct: 181 FIVTLVQNNQLVSLKRKRPLLLNTNGAQKKNLFQHIVKEPTDNHHHKVPHSRTEGLKPRE 240

Query: 241 RISDDIIIYDVTDDNADEENIPVIPETNEDVISDPSNCSQYPDIVIVEDDNEDEYAPVIQ 300
           RISDDIIIYDVTDDNADEENIPVIPETNEDVISDPSNCSQYPDIVIVEDDNEDEYAPVIQ
Sbjct: 241 RISDDIIIYDVTDDNADEENIPVIPETNEDVISDPSNCSQYPDIVIVEDDNEDEYAPVIQ 300

Query: 301 SGEQNEPARESLSSGSDGSSPLMSSAVQLNGSSSLTSEDPVTMMDSILNDNINLLGKVEL 360
           SGEQNEPARESLSSGSDGSSPLMSSAVQLNGSSSLTSEDPVTMMDSILNDNINLLGKVEL
Sbjct: 301 SGEQNEPARESLSSGSDGSSPLMSSAVQLNGSSSLTSEDPVTMMDSILNDNINLLGKVEL 360

Query: 361 LDYLDSIDCSLEDFQAMLSGRQFSIDPDLLVD------------------SENKGLETTK 402
           LDYLDSIDCSLEDFQAMLSGRQFSIDPDLLVD                  SENKGLETTK
Sbjct: 361 LDYLDSIDCSLEDFQAMLSGRQFSIDPDLLVDLFTSSVQMNPTDYINNTKSENKGLETTK 420

Query: 403 NNVVQPVSEEGRKSKSKPDKQLIQYTAFPLLAFLDGNPASSVEQASTTASSEVLSSVDKP 462
           NNVVQPVSEEGRKSKSKPDKQLIQYTAFPLLAFLDGNPASSVEQASTTASSEVLSSVDKP
Sbjct: 421 NNVVQPVSEEGRKSKSKPDKQLIQYTAFPLLAFLDGNPASSVEQASTTASSEVLSSVDKP 480

Query: 463 IEVDELLDSSLDPEPTQSKLVRLEPLTEAEASEATLFYLCELAPAPLDSDMPLLDS 518
           IEVDELLDSSLDPEPTQSKLVRLEPLTEAEASEATLFYLCELAPAPLDSDMPLLDS
Sbjct: 481 IEVDELLDSSLDPEPTQSKLVRLEPLTEAEASEATLFYLCELAPAPLDSDMPLLDS 536


>gi|5031767 heat shock transcription factor 1 [Homo sapiens]
          Length = 529

 Score =  282 bits (721), Expect = 6e-76
 Identities = 183/477 (38%), Positives = 260/477 (54%), Gaps = 51/477 (10%)

Query: 5   SNVPAFLSKLWTLVEETHTNEFITWSQNGQSFLVLDEQRFAKEILPKYFKHNNMASFVRQ 64
           SNVPAFL+KLWTLV +  T+  I WS +G SF V D+ +FAKE+LPKYFKHNNMASFVRQ
Sbjct: 13  SNVPAFLTKLWTLVSDPDTDALICWSPSGNSFHVFDQGQFAKEVLPKYFKHNNMASFVRQ 72

Query: 65  LNMYGFRKVVHID-SGIVKQERDGPVEFQHPYFKQGQDDLLENIKRK---VSSSKPEENK 120
           LNMYGFRKVVHI+  G+VK ERD   EFQHP F +GQ+ LLENIKRK   VS+ K E+ K
Sbjct: 73  LNMYGFRKVVHIEQGGLVKPERD-DTEFQHPCFLRGQEQLLENIKRKVTSVSTLKSEDIK 131

Query: 121 IRQEDLTKIISSAQKVQIKQETIESRLSELKSENESLWKEVSELRAKHAQQQQVIRKIVQ 180
           IRQ+ +TK+++  Q ++ KQE ++S+L  +K ENE+LW+EV+ LR KHAQQQ+V+ K++Q
Sbjct: 132 IRQDSVTKLLTDVQLMKGKQECMDSKLLAMKHENEALWREVASLRQKHAQQQKVVNKLIQ 191

Query: 181 FIVTLVQNNQLVSLKRKRPLLLNTNG---AQKKNLFQHIVKEPTDNHHHKVP---HSRTE 234
           F+++LVQ+N+++ +KRK PL+LN +G   +  K   Q  ++    +  +  P   +S + 
Sbjct: 192 FLISLVQSNRILGVKRKIPLMLNDSGSAHSMPKYSRQFSLEHVHGSGPYSAPSPAYSSSS 251

Query: 235 GLKPRERISDDIIIYDVTDDNADEENIPVIPETNEDVISDPSNCSQYPDIVIVEDDNEDE 294
              P    S   II D+T      E  P  P  +     D    S  P + + E+     
Sbjct: 252 LYAPDAVASSGPIISDIT------ELAPASPMASPGGSIDERPLSSSPLVRVKEEPPSPP 305

Query: 295 YAPVIQSGEQNEPARES--------LSSGSDGSSPLMSSAVQLNGSSSLT-------SED 339
            +P ++      P+           + S    S P  +S   L  +   T       S  
Sbjct: 306 QSPRVEEASPGRPSSVDTLLSPTALIDSILRESEPAPASVTALTDARGHTDTEGRPPSPP 365

Query: 340 PVTMMDSILNDNINLLGKVELLDYLDSIDCSLEDFQAMLSGRQFSIDPDLL--------- 390
           P +  +  L  ++  L K EL D+LD++D +L++ Q MLS   FS+D   L         
Sbjct: 366 PTSTPEKCL--SVACLDKNELSDHLDAMDSNLDNLQTMLSSHGFSVDTSALLDLFSPSVT 423

Query: 391 --------VDSENKGLETTKNNVVQPVSEEGRKSKSKPDKQLIQYTAFPLLAFLDGN 439
                   +DS    ++   +    P   E   S     KQL+ YTA PL     G+
Sbjct: 424 VPDMSLPDLDSSLASIQELLSPQEPPRPPEAENSSPDSGKQLVHYTAQPLFLLDPGS 480


>gi|100913209 heat shock transcription factor 4 isoform b [Homo
           sapiens]
          Length = 492

 Score =  193 bits (490), Expect = 4e-49
 Identities = 102/201 (50%), Positives = 140/201 (69%), Gaps = 3/201 (1%)

Query: 5   SNVPAFLSKLWTLVEETHTNEFITWSQNGQSFLVLDEQRFAKEILPKYFKHNNMASFVRQ 64
           S VPAFL KLW LV +  T+  I WS +G SFLV D+ RFAKE+LP+YFKH+NMASFVRQ
Sbjct: 15  SPVPAFLGKLWALVGDPGTDHLIRWSPSGTSFLVSDQSRFAKEVLPQYFKHSNMASFVRQ 74

Query: 65  LNMYGFRKVVHID-SGIVKQERDGPVEFQHPYFKQGQDDLLENIKRKVSSSKPEENKIRQ 123
           LNMYGFRKVV I+  G+++ ERD  VEFQHP F +G++ LLE ++RKV + + ++ + R 
Sbjct: 75  LNMYGFRKVVSIEQGGLLRPERD-HVEFQHPSFVRGREQLLERVRRKVPALRGDDGRWRP 133

Query: 124 EDLTKIISSAQKVQIKQETIESRLSELKSENESLWKEVSELRAKHAQQQQVIRKIVQFIV 183
           EDL +++   Q ++  QE+ E+RL EL+ +NE LW+EV  LR  H QQ +VI K++Q + 
Sbjct: 134 EDLGRLLGEVQALRGVQESTEARLRELRQQNEILWREVVTLRQSHGQQHRVIGKLIQCLF 193

Query: 184 TLVQ-NNQLVSLKRKRPLLLN 203
             +Q        KRK  L+L+
Sbjct: 194 GPLQAGPSNAGGKRKLSLMLD 214


>gi|100913211 heat shock transcription factor 4 isoform a [Homo
           sapiens]
          Length = 462

 Score =  193 bits (490), Expect = 4e-49
 Identities = 102/201 (50%), Positives = 140/201 (69%), Gaps = 3/201 (1%)

Query: 5   SNVPAFLSKLWTLVEETHTNEFITWSQNGQSFLVLDEQRFAKEILPKYFKHNNMASFVRQ 64
           S VPAFL KLW LV +  T+  I WS +G SFLV D+ RFAKE+LP+YFKH+NMASFVRQ
Sbjct: 15  SPVPAFLGKLWALVGDPGTDHLIRWSPSGTSFLVSDQSRFAKEVLPQYFKHSNMASFVRQ 74

Query: 65  LNMYGFRKVVHID-SGIVKQERDGPVEFQHPYFKQGQDDLLENIKRKVSSSKPEENKIRQ 123
           LNMYGFRKVV I+  G+++ ERD  VEFQHP F +G++ LLE ++RKV + + ++ + R 
Sbjct: 75  LNMYGFRKVVSIEQGGLLRPERD-HVEFQHPSFVRGREQLLERVRRKVPALRGDDGRWRP 133

Query: 124 EDLTKIISSAQKVQIKQETIESRLSELKSENESLWKEVSELRAKHAQQQQVIRKIVQFIV 183
           EDL +++   Q ++  QE+ E+RL EL+ +NE LW+EV  LR  H QQ +VI K++Q + 
Sbjct: 134 EDLGRLLGEVQALRGVQESTEARLRELRQQNEILWREVVTLRQSHGQQHRVIGKLIQCLF 193

Query: 184 TLVQ-NNQLVSLKRKRPLLLN 203
             +Q        KRK  L+L+
Sbjct: 194 GPLQAGPSNAGGKRKLSLMLD 214


>gi|122937277 heat shock transcription factor family member 5 [Homo
           sapiens]
          Length = 596

 Score = 67.0 bits (162), Expect = 4e-11
 Identities = 44/124 (35%), Positives = 63/124 (50%), Gaps = 20/124 (16%)

Query: 10  FLSKLWTLVEETHTNEFITWSQNGQSFLVLDEQRFAKEIL-----------------PKY 52
           F +KLW LV        I W   G+  L+ D+  F  E+L                 P+ 
Sbjct: 14  FPAKLWRLVNSPRYRS-IRWDGRGEGLLI-DQPLFEAELLSPPGPGGGGGTAGAGAEPEL 71

Query: 53  FKHNNMASFVRQLNMYGFRKVVHIDSGIVKQERDGPV-EFQHPYFKQGQDDLLENIKRKV 111
           FK  +  SF+RQLN+YGFRKVV    G  K   +GP+  F +P+F++ Q  LL ++KR  
Sbjct: 72  FKTTSFTSFIRQLNLYGFRKVVLGGPGGGKPAGNGPLHHFHNPHFRRDQPQLLVHLKRLT 131

Query: 112 SSSK 115
           S++K
Sbjct: 132 SANK 135


>gi|50312655 heat shock transcription factor, Y-linked 1 isoform 1
           [Homo sapiens]
          Length = 401

 Score = 59.3 bits (142), Expect = 8e-09
 Identities = 51/188 (27%), Positives = 89/188 (47%), Gaps = 26/188 (13%)

Query: 10  FLSKLWTLVEETHTNEFITWSQNGQSFLVLDEQRFAKEILP-----KYFKHNNMASFVRQ 64
           F  KLW +VE       I+W +NG + +V++E+ F KEIL      + F+ + + SFVRQ
Sbjct: 80  FPRKLWKIVESDQFKS-ISWDENG-TCIVINEELFKKEILETKAPYRIFQTDAIKSFVRQ 137

Query: 65  LNMYGFRKVVH------IDSGIVKQERDGPV-----EFQHPYFKQGQDDLLENIKRK--V 111
           LN+YGF K+          +  + +E++  V      + +P FK+G   LL  +KR+  V
Sbjct: 138 LNLYGFSKIQQNFQRSAFLATFLSEEKESSVLSKLKFYYNPNFKRGYPQLLVRVKRRIGV 197

Query: 112 SSSKPEENKIRQEDLTKIISSAQKVQIKQETIESRLSELKSENESLWKEVSELRAKHAQQ 171
            ++ P      ++   K   +   ++     + +  SE     ESL+     L     ++
Sbjct: 198 KNASPISTLFNEDFNKKHFRAGANMENHNSALAAEASE-----ESLFSASKNLNMPLTRE 252

Query: 172 QQVIRKIV 179
             V R+I+
Sbjct: 253 SSV-RQII 259


>gi|32526913 heat shock transcription factor, Y linked 2 isoform 1
           [Homo sapiens]
          Length = 401

 Score = 59.3 bits (142), Expect = 8e-09
 Identities = 51/188 (27%), Positives = 89/188 (47%), Gaps = 26/188 (13%)

Query: 10  FLSKLWTLVEETHTNEFITWSQNGQSFLVLDEQRFAKEILP-----KYFKHNNMASFVRQ 64
           F  KLW +VE       I+W +NG + +V++E+ F KEIL      + F+ + + SFVRQ
Sbjct: 80  FPRKLWKIVESDQFKS-ISWDENG-TCIVINEELFKKEILETKAPYRIFQTDAIKSFVRQ 137

Query: 65  LNMYGFRKVVH------IDSGIVKQERDGPV-----EFQHPYFKQGQDDLLENIKRK--V 111
           LN+YGF K+          +  + +E++  V      + +P FK+G   LL  +KR+  V
Sbjct: 138 LNLYGFSKIQQNFQRSAFLATFLSEEKESSVLSKLKFYYNPNFKRGYPQLLVRVKRRIGV 197

Query: 112 SSSKPEENKIRQEDLTKIISSAQKVQIKQETIESRLSELKSENESLWKEVSELRAKHAQQ 171
            ++ P      ++   K   +   ++     + +  SE     ESL+     L     ++
Sbjct: 198 KNASPISTLFNEDFNKKHFRAGANMENHNSALAAEASE-----ESLFSASKNLNMPLTRE 252

Query: 172 QQVIRKIV 179
             V R+I+
Sbjct: 253 SSV-RQII 259


>gi|239752444 PREDICTED: similar to heat shock transcription factor
           family, X linked 1 [Homo sapiens]
          Length = 354

 Score = 58.5 bits (140), Expect = 1e-08
 Identities = 37/107 (34%), Positives = 66/107 (61%), Gaps = 11/107 (10%)

Query: 9   AFLSKLWTLVEETHTNEFITWSQNGQSFLVLDEQRFAKEILPK-----YFKHNNMASFVR 63
           +F  KLWT+VEE  T + ++W+ +G + +++D+  F +E+L +      FK +++ SF+R
Sbjct: 82  SFPRKLWTIVEED-TFKSVSWNDDGDA-VIIDKDLFQREVLQRKGAERIFKTDSLTSFIR 139

Query: 64  QLNMYGFRKVVHIDSGIVKQERDGPVEFQHPYFKQGQDDLLENIKRK 110
           QLN+YGF K    +S   K+     + + +  F++ +  LLENI+RK
Sbjct: 140 QLNLYGFCKTRPSNSPGNKK----MMIYCNSNFQRDKPRLLENIQRK 182


>gi|239746964 PREDICTED: similar to heat shock transcription factor
           family, X linked 1 [Homo sapiens]
          Length = 333

 Score = 58.5 bits (140), Expect = 1e-08
 Identities = 37/107 (34%), Positives = 66/107 (61%), Gaps = 11/107 (10%)

Query: 9   AFLSKLWTLVEETHTNEFITWSQNGQSFLVLDEQRFAKEILPK-----YFKHNNMASFVR 63
           +F  KLWT+VEE  T + ++W+ +G + +++D+  F +E+L +      FK +++ SF+R
Sbjct: 82  SFPRKLWTIVEED-TFKSVSWNDDGDA-VIIDKDLFQREVLQRKGAERIFKTDSLTSFIR 139

Query: 64  QLNMYGFRKVVHIDSGIVKQERDGPVEFQHPYFKQGQDDLLENIKRK 110
           QLN+YGF K    +S   K+     + + +  F++ +  LLENI+RK
Sbjct: 140 QLNLYGFCKTRPSNSPGNKK----MMIYCNSNFQRDKPRLLENIQRK 182


>gi|169216697 PREDICTED: heat shock transcription factor family, X
           linked 2 [Homo sapiens]
          Length = 423

 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 43/118 (36%), Positives = 59/118 (50%), Gaps = 20/118 (16%)

Query: 10  FLSKLWTLVEETHTNEF--ITWSQNGQSFLVLDEQRFAKEILP-----KYFKHNNMASFV 62
           F  KLW LV    +N+F  I W  +G +  V++++ F KEIL      K F   ++ SF 
Sbjct: 99  FPQKLWRLVS---SNQFSSIWWDDSG-ACRVINQKLFEKEILKRDVAHKVFATTSIKSFF 154

Query: 63  RQLNMYGFRK--------VVHIDSGIVKQERDGPVEFQ-HPYFKQGQDDLLENIKRKV 111
           RQLN+YGFRK           I S          +EF  HPYF++    LL  +KR+V
Sbjct: 155 RQLNLYGFRKRRQCTFRTFTRIFSAKRLVSILNKLEFYCHPYFQRDSPHLLVRMKRRV 212


>gi|24211017 heat shock transcription factor, Y-linked 1 isoform 2
           [Homo sapiens]
          Length = 203

 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 29/69 (42%), Positives = 43/69 (62%), Gaps = 7/69 (10%)

Query: 10  FLSKLWTLVEETHTNEFITWSQNGQSFLVLDEQRFAKEILP-----KYFKHNNMASFVRQ 64
           F  KLW +VE       I+W +NG + +V++E+ F KEIL      + F+ + + SFVRQ
Sbjct: 80  FPRKLWKIVESDQFKS-ISWDENG-TCIVINEELFKKEILETKAPYRIFQTDAIKSFVRQ 137

Query: 65  LNMYGFRKV 73
           LN+YGF K+
Sbjct: 138 LNLYGFSKI 146


>gi|7706603 heat shock transcription factor family, X linked 1 [Homo
           sapiens]
          Length = 423

 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 43/118 (36%), Positives = 59/118 (50%), Gaps = 20/118 (16%)

Query: 10  FLSKLWTLVEETHTNEF--ITWSQNGQSFLVLDEQRFAKEILP-----KYFKHNNMASFV 62
           F  KLW LV    +N+F  I W  +G +  V++++ F KEIL      K F   ++ SF 
Sbjct: 99  FPQKLWRLVS---SNQFSSIWWDDSG-ACRVINQKLFEKEILKRDVAHKVFATTSIKSFF 154

Query: 63  RQLNMYGFRK--------VVHIDSGIVKQERDGPVEFQ-HPYFKQGQDDLLENIKRKV 111
           RQLN+YGFRK           I S          +EF  HPYF++    LL  +KR+V
Sbjct: 155 RQLNLYGFRKRRQCTFRTFTRIFSAKRLVSILNKLEFYCHPYFQRDSPHLLVRMKRRV 212


>gi|50312659 heat shock transcription factor, Y linked 2 isoform 2
           [Homo sapiens]
          Length = 203

 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 29/69 (42%), Positives = 43/69 (62%), Gaps = 7/69 (10%)

Query: 10  FLSKLWTLVEETHTNEFITWSQNGQSFLVLDEQRFAKEILP-----KYFKHNNMASFVRQ 64
           F  KLW +VE       I+W +NG + +V++E+ F KEIL      + F+ + + SFVRQ
Sbjct: 80  FPRKLWKIVESDQFKS-ISWDENG-TCIVINEELFKKEILETKAPYRIFQTDAIKSFVRQ 137

Query: 65  LNMYGFRKV 73
           LN+YGF K+
Sbjct: 138 LNLYGFSKI 146


>gi|42734430 polymerase I and transcript release factor [Homo
           sapiens]
          Length = 390

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 38/151 (25%), Positives = 68/151 (45%), Gaps = 18/151 (11%)

Query: 126 LTKIISSAQKVQIKQETIESRLSELKSENESLWKEVSELRAKHAQQQQVIRKIVQFIVTL 185
           L KII +  ++Q+ Q  +E R +E++   +S+  E+S+L   HA     + K+++ +  +
Sbjct: 58  LDKIIGAVDQIQLTQAQLEERQAEMEGAVQSIQGELSKLGKAHATTSNTVSKLLEKVRKV 117

Query: 186 VQNNQLV--SLKRKRPLL--LNTNGAQ-------KKNLFQHIVKEPTD-------NHHHK 227
             N + V  SL+R+   +  L  N A+       K  ++Q  VK P              
Sbjct: 118 SVNVKTVRGSLERQAGQIKKLEVNEAELLRRRNFKVMIYQDEVKLPAKLSISKSLKESEA 177

Query: 228 VPHSRTEGLKPRERISDDIIIYDVTDDNADE 258
           +P    E L   ER  +D    +++ D A E
Sbjct: 178 LPEKEGEELGEGERPEEDAAALELSSDEAVE 208


>gi|56550047 uveal autoantigen with coiled-coil domains and ankyrin
           repeats isoform 2 [Homo sapiens]
          Length = 1403

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 37/157 (23%), Positives = 72/157 (45%), Gaps = 20/157 (12%)

Query: 74  VHIDSGIVKQERDG-PVEFQHPY--------FKQGQDDLLENIKRKVS--SSKPEENKIR 122
           V++D+ ++K++     +E ++ Y         K+  D +++++ RK+   + K  E K+ 
Sbjct: 709 VYLDNKLLKEQAHNLTIEMKNHYVPLKVSEDMKKSHDAIIDDLNRKLLDVTQKYTEKKLE 768

Query: 123 QE-------DLTKIISSAQKVQIKQETIESRLSELKSENESLWKEVSELRAKHAQQQQVI 175
            E        L+K +S  + V +  E  E  +  LKS    L K++SEL+ K  + Q+ I
Sbjct: 769 MEKLLLENDSLSKDVSRLETVFVPPEKHEKEIIALKSNIVELKKQLSELKKKCGEDQEKI 828

Query: 176 RKIVQFIVTL--VQNNQLVSLKRKRPLLLNTNGAQKK 210
             +      L  + +NQ V +K    + +  N    K
Sbjct: 829 HALTSENTNLKKMMSNQYVPVKTHEEVKMTLNDTLAK 865



 Score = 30.0 bits (66), Expect = 5.3
 Identities = 22/91 (24%), Positives = 46/91 (50%), Gaps = 6/91 (6%)

Query: 115  KPEENKIRQEDLTKIISSAQKVQIKQETIESR----LSELKSENESLWKEVSELRAKHAQ 170
            K EE++ + E+++K+ S  Q  +   + +E+R    LS+ K+    L  ++S L  K A 
Sbjct: 1177 KEEESQNKMEEVSKLQSEVQNTKQALKKLETREVVDLSKYKATKSDLETQISSLNEKLAN 1236

Query: 171  QQQVIRKIVQFIVTLVQNNQLVSLKRKRPLL 201
              +   ++ + +  L    + +S K ++ LL
Sbjct: 1237 LNRKYEEVCEEV--LHAKKKEISAKDEKELL 1265


>gi|59850762 uveal autoantigen with coiled-coil domains and ankyrin
           repeats isoform 1 [Homo sapiens]
          Length = 1416

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 37/157 (23%), Positives = 72/157 (45%), Gaps = 20/157 (12%)

Query: 74  VHIDSGIVKQERDG-PVEFQHPY--------FKQGQDDLLENIKRKVS--SSKPEENKIR 122
           V++D+ ++K++     +E ++ Y         K+  D +++++ RK+   + K  E K+ 
Sbjct: 722 VYLDNKLLKEQAHNLTIEMKNHYVPLKVSEDMKKSHDAIIDDLNRKLLDVTQKYTEKKLE 781

Query: 123 QE-------DLTKIISSAQKVQIKQETIESRLSELKSENESLWKEVSELRAKHAQQQQVI 175
            E        L+K +S  + V +  E  E  +  LKS    L K++SEL+ K  + Q+ I
Sbjct: 782 MEKLLLENDSLSKDVSRLETVFVPPEKHEKEIIALKSNIVELKKQLSELKKKCGEDQEKI 841

Query: 176 RKIVQFIVTL--VQNNQLVSLKRKRPLLLNTNGAQKK 210
             +      L  + +NQ V +K    + +  N    K
Sbjct: 842 HALTSENTNLKKMMSNQYVPVKTHEEVKMTLNDTLAK 878



 Score = 30.0 bits (66), Expect = 5.3
 Identities = 22/91 (24%), Positives = 46/91 (50%), Gaps = 6/91 (6%)

Query: 115  KPEENKIRQEDLTKIISSAQKVQIKQETIESR----LSELKSENESLWKEVSELRAKHAQ 170
            K EE++ + E+++K+ S  Q  +   + +E+R    LS+ K+    L  ++S L  K A 
Sbjct: 1190 KEEESQNKMEEVSKLQSEVQNTKQALKKLETREVVDLSKYKATKSDLETQISSLNEKLAN 1249

Query: 171  QQQVIRKIVQFIVTLVQNNQLVSLKRKRPLL 201
              +   ++ + +  L    + +S K ++ LL
Sbjct: 1250 LNRKYEEVCEEV--LHAKKKEISAKDEKELL 1278


>gi|150010552 FK506 binding protein 15, 133kDa [Homo sapiens]
          Length = 1219

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 46/203 (22%), Positives = 92/203 (45%), Gaps = 20/203 (9%)

Query: 17  LVEETHTNEFITWSQNGQSFLVLDEQRFAKEILPKYFKHNNMASFVRQLNMYGFRKVVHI 76
           L+ E   N   T ++N Q+ ++  EQ  AK           +A+   Q++    +   H 
Sbjct: 611 LMMEKRNNSLQTATENTQARVLHAEQEKAKVT-------EELAAATAQVSHLQLKMTAH- 662

Query: 77  DSGIVKQERDGPVEFQHPYFKQGQDDLLENIKRKVSSSKPEENKIRQEDLTKIISSAQ-- 134
                 Q+++  ++ Q     + + DLL     KV +   E  +  ++  +K  S  Q  
Sbjct: 663 ------QKKETELQMQLTESLK-ETDLLRGQLTKVQAKLSELQETSEQAQSKFKSEKQNR 715

Query: 135 -KVQIKQETIESRLSELKSENESLWKEVSELRAKHAQQQQVIRKIVQFIVTLVQN--NQL 191
            ++++K  ++E  L++L+ E ESL K +SE + K AQ++    + +  I    Q   ++L
Sbjct: 716 KQLELKVTSLEEELTDLRVEKESLEKNLSERKKKSAQERSQAEEEIDEIRKSYQEELDKL 775

Query: 192 VSLKRKRPLLLNTNGAQKKNLFQ 214
             L +K  +  +   A++ +L Q
Sbjct: 776 RQLLKKTRVSTDQAAAEQLSLVQ 798


>gi|149363642 coiled-coil domain containing 144A [Homo sapiens]
          Length = 1427

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 32/119 (26%), Positives = 62/119 (52%), Gaps = 9/119 (7%)

Query: 103  LLENIKRKVSSSKPEENKIRQEDLTKIISSAQKVQI-KQETIESRLSELKSENESLWKEV 161
            +LE ++R +S ++ ++ +  Q  + +I  S  K  I KQE++E RLS+L+SEN  L +++
Sbjct: 999  ILERVQRDLSQTQCQKKETEQ--MYQIEQSKLKKYIAKQESVEERLSQLQSENMLLRQQL 1056

Query: 162  SELRAKHAQQQQVIRKIVQFIVTLVQN------NQLVSLKRKRPLLLNTNGAQKKNLFQ 214
             +   K   Q++    I     +  +N       Q++SL+ K   L++     K+ + Q
Sbjct: 1057 DDAHKKANSQEKTSSTIQDQFHSAAKNLQAESEKQILSLQEKNKELMDEYNHLKERMDQ 1115



 Score = 30.0 bits (66), Expect = 5.3
 Identities = 33/127 (25%), Positives = 60/127 (47%), Gaps = 26/127 (20%)

Query: 101 DDLLENIKRKVSSSKPEENKIRQEDLTKIISSAQKVQIKQETIESRLSELKSENES---- 156
           D L   +K+  +     +N++ +   TK+    QK++ ++E  + RL+ LK ENE     
Sbjct: 657 DQLTVKLKQMENMVSVLQNELSETKKTKLQLELQKIEWEKELYDLRLA-LKQENEEKRNA 715

Query: 157 ---LWKEVSELRAKHAQ-------QQQV---IRKIVQFIVTLVQNNQLVSLKRKRPLLLN 203
                K+  +LR K  +       +QQ+   +R++V+ + T+  N  LV  +R       
Sbjct: 716 DMLYNKDSEQLRIKEEECGKVVETKQQLKWNLRRLVKELRTVRNNLDLVVQER------- 768

Query: 204 TNGAQKK 210
            N AQK+
Sbjct: 769 -NDAQKQ 774


>gi|11968023 zinc finger protein 106 homolog [Homo sapiens]
          Length = 1883

 Score = 40.0 bits (92), Expect = 0.005
 Identities = 76/349 (21%), Positives = 131/349 (37%), Gaps = 51/349 (14%)

Query: 208  QKKNLFQHIVKEPTDNHHHKVPHSRTEGLKPRER----ISDDIII---YDVTDDNADEEN 260
            Q +    H+ +E T          R E +  + R    +S D II   +   D N+ E +
Sbjct: 902  QSQKATMHLKQEVTPRAASLRTGERAENVATQRRHSAQLSSDHIIPLMHLAKDLNSQERS 961

Query: 261  IPVIPETNEDVISDPSNC---SQYPDIVIVEDDNEDEYAPVIQSGEQNE--PARESLSSG 315
            IP     N    +   NC   S    + I    +    +      EQN+    R+   + 
Sbjct: 962  IPPSENQNSQESNGEGNCLSSSASSALAISSLADAATDSSCTSGAEQNDGQSIRKKRRAT 1021

Query: 316  SDGSSPLMSSAVQLNGSSSLTSEDPVTMMDSILNDNINLLGKVELLDYLDSIDCSLEDFQ 375
             DGSSP + S  + N    +  +   + +D +LN +   L + EL   L  +D +L   +
Sbjct: 1022 GDGSSPELPSLERKNKRRKIKGKKERSQVDQLLNIS---LREEELSKSLQCMDNNLLQAR 1078

Query: 376  AMLSGRQFSIDPDLL----VDSENKGLETTKNNVVQPVSE-----------------EGR 414
            A L      +   L+    +  E   L T +  ++Q + E                 E R
Sbjct: 1079 AALQTAYVEVQRLLMLKQQITMEMSALRTHRIQILQGLQETYEPSEHPDQVPCSLTRERR 1138

Query: 415  KSKSKP--DKQLIQYTAFPLLAFLDGNPASSVEQASTTASSEVLSSVDKPIEVDELLDSS 472
             S+S+   D  L+    FPL  FL+  P+S V  + T AS ++ +S              
Sbjct: 1139 NSRSQTSIDAALLPTPFFPL--FLE-PPSSHVSPSPTGASLQITTS-------PTFQTHG 1188

Query: 473  LDPEPTQSKLVRLEPLTEAEASEATLF---YLCELAPAPLDSDMPLLDS 518
              P P  S  ++ EP++  +            C ++   L+++  + DS
Sbjct: 1189 SVPAPDSSVQIKQEPMSPEQDENVNAVPPSSACNVSKELLEANREISDS 1237


>gi|41393608 reticulon 3 isoform b [Homo sapiens]
          Length = 1013

 Score = 39.7 bits (91), Expect = 0.007
 Identities = 62/281 (22%), Positives = 114/281 (40%), Gaps = 46/281 (16%)

Query: 243 SDDIIIYDVTDDNADEEN---------IP-VIPETNEDVISDPSNCSQYPDIVIVEDDNE 292
           SDD +I D+T D + E N         IP  + +T E  I +  +C +       E+   
Sbjct: 481 SDDTVIEDITADTSFENNKIQAEKPVSIPSAVVKTGEREIKEIPSCER-------EEKTS 533

Query: 293 DEYAPVIQSGE--QNEPARESLSSGSDGS-SPLMSSAVQLNGSSSLTSEDPVTMMDSILN 349
             +  ++   E  Q++P     S  S+ + S +  + V L   S +  E P+T  +  L 
Sbjct: 534 KNFEELVSDSELHQDQPDILGRSPASEAACSKVPDTNVSLEDVSEVAPEKPITTENPKLP 593

Query: 350 DNI--NLLGKVELLDYLDSIDCSLEDFQAMLSGRQF-----SIDPDLL---VDSENKGLE 399
             +  N+  + E      S++ +   +   L G+       S   DL+    ++ +KG+ 
Sbjct: 594 STVSPNVFNETEF-----SLNVTTSAYLESLHGKNVKHIDDSSPEDLIAAFTETRDKGIV 648

Query: 400 TTKNNVVQPVSEEGRKSKSKPDKQLIQYTAFPLLAFLDGNPASSVEQASTTASSE---VL 456
            ++ N  + +SE+    K+ P  +++           D     S EQ+  T  SE   V 
Sbjct: 649 DSERNAFKAISEKMTDFKTTPPVEVLHENESGGSEIKDIGSKYS-EQSKETNGSEPLGVF 707

Query: 457 SSVDKPIEVDELLDSSLDPEPTQSKLVRLEPLTEAEASEAT 497
            +   P+       +SLD E  Q  +  L+ L E +  ++T
Sbjct: 708 PTQGTPV-------ASLDLEQEQLTIKALKELGERQVEKST 741


>gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo
            sapiens]
          Length = 1940

 Score = 39.7 bits (91), Expect = 0.007
 Identities = 24/77 (31%), Positives = 43/77 (55%), Gaps = 5/77 (6%)

Query: 100  QDDLLENIKRKVSSSKPEENKIRQEDLTKIISSAQKVQIKQE----TIESRLSELKSENE 155
            Q D L+ +K+K+   K  E K+  +DL+  + S  K +   E    T+E +LSE + +NE
Sbjct: 1207 QIDNLQRVKQKLEKEK-SEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNE 1265

Query: 156  SLWKEVSELRAKHAQQQ 172
             + + +SEL  + ++ Q
Sbjct: 1266 EIQRSLSELTTQKSRLQ 1282


>gi|239747446 PREDICTED: similar to Neuroblastoma breakpoint family
           member 6-like protein [Homo sapiens]
          Length = 298

 Score = 39.3 bits (90), Expect = 0.009
 Identities = 32/139 (23%), Positives = 64/139 (46%), Gaps = 6/139 (4%)

Query: 105 ENIKRKVSSSKPEENKIRQEDLTKIISSAQKVQIKQETIESRLSELKSENESLWKEVSEL 164
           E  K  + S   EE + ++ +L ++  SA +++I    I+++  EL      L +++ E 
Sbjct: 62  EECKDLIESVLEEEVQFQERELAELPRSAARLRIHDPLIQAQAEELTH----LRQKIQEG 117

Query: 165 RAKHAQQQQVIRKIVQFIVTLVQNNQLVSLKRKRPLLLNTNGAQKKNLFQHIVKEPTDNH 224
           R       Q ++  V+    L++N  +   +R+R       G+Q   +   + K  T+NH
Sbjct: 118 RGVCYLFTQHVKNTVKSFEGLLRNTDIAYYQRQRFCEQMVQGSQLTEIL--VRKLATENH 175

Query: 225 HHKVPHSRTEGLKPRERIS 243
           + K    R + L PR  ++
Sbjct: 176 NGKKNEDRQKPLAPRSELA 194


>gi|154354990 ankyrin repeat domain 26 [Homo sapiens]
          Length = 1710

 Score = 39.3 bits (90), Expect = 0.009
 Identities = 58/295 (19%), Positives = 123/295 (41%), Gaps = 36/295 (12%)

Query: 89   VEFQHPYFKQGQDDL-LENIKRKVSSSKPEENKIRQEDLTKIISSAQKVQIKQETIESRL 147
            +EF H      +  L LE +++ +S ++ +  ++ Q+   + +    K   KQE++E RL
Sbjct: 1078 IEFHHTRDALREKTLGLERVQKDLSQTQCQMKEMEQKYQNEQVK-VNKYIGKQESVEERL 1136

Query: 148  SELKSENESLWKEVSELRAKHAQQQQVIRKIVQFIVTLVQNNQLVSLKRKRPLLLNTNGA 207
            S+L+SEN  L +++ +   K   +++ +  I      +VQ  Q  S   K+ LLL     
Sbjct: 1137 SQLQSENMLLRQQLDDAHNKADNKEKTVINIQDQFHAIVQKLQAES--EKQSLLLEERNK 1194

Query: 208  QKKNLFQHIVKEPTDNHHHKVPHSRTEGLKPRERISDDIIIYDVTDDNADEENIPVIPET 267
            +  +   H+ KE    + +             E+   ++++  +  + AD      + E 
Sbjct: 1195 ELISECNHL-KERQYQYEN-------------EKAEREVVVRQLQQELADTLKKQSMSEA 1240

Query: 268  NEDVISDPSNCSQYPDIVIVEDDNEDEYAPVIQSGEQNEPARESLSSGSDGSSPLMSSAV 327
            + +V       S+Y   + +ED+ +D    + Q   Q + A++  +     +  +     
Sbjct: 1241 SLEV------TSRYR--INLEDETQDLKKKLGQIRNQLQEAQDRHTEAVRCAEKMQDHKQ 1292

Query: 328  QLNGSSSLTSEDPVTMMDSILNDNINLLGK----------VELLDYLDSIDCSLE 372
            +L   ++         MD I     NLL             +L++   S++C+L+
Sbjct: 1293 KLEKDNAKLKVTVKKQMDKIEELQKNLLNANLSEDEKEQLKKLMELKQSLECNLD 1347



 Score = 29.6 bits (65), Expect = 6.9
 Identities = 26/107 (24%), Positives = 49/107 (45%), Gaps = 13/107 (12%)

Query: 97  KQGQDDLLENIKRKVSSSKPEENKIRQE--DLTKIISSAQKVQI-----------KQETI 143
           KQ  +  L+ ++ ++ + K   N++ QE  D  + +S  Q  ++           KQ+ I
Sbjct: 830 KQQLELSLQTLEMELRTVKSNLNQVVQERNDAQRQLSREQNARMLQDGILTNHLSKQKEI 889

Query: 144 ESRLSELKSENESLWKEVSELRAKHAQQQQVIRKIVQFIVTLVQNNQ 190
           E    ++ SEN    +E  +L  K++  Q+ I  +   I T+   NQ
Sbjct: 890 EMAQKKMNSENSHSHEEEKDLSHKNSMLQEEIAMLRLEIDTIKNQNQ 936


>gi|16445033 ACRC protein [Homo sapiens]
          Length = 691

 Score = 38.5 bits (88), Expect = 0.015
 Identities = 27/90 (30%), Positives = 40/90 (44%), Gaps = 5/90 (5%)

Query: 250 DVTDDNADEENIPVIPETNEDVISDPSNCSQYPDIVIVEDDNEDEYAPVIQSGEQNEPAR 309
           D +DDN+D+ ++P     + DV  D S+ S  PD     D ++D  AP   S +   P  
Sbjct: 203 DSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPD-----DSSDDSEAPDDSSDDSEAPDD 257

Query: 310 ESLSSGSDGSSPLMSSAVQLNGSSSLTSED 339
            S  S +   S   S A   +   S  S+D
Sbjct: 258 SSDDSEAPDDSSDDSEAPDDSSDDSEASDD 287



 Score = 34.3 bits (77), Expect = 0.28
 Identities = 26/91 (28%), Positives = 41/91 (45%), Gaps = 8/91 (8%)

Query: 250 DVTDDNADEENIPVIPETNEDVISDPSNCSQYPDIVIVEDDNEDEYAPVIQSGEQNEPAR 309
           DV DD++D+ ++P     + +   D S+ S+ PD     D ++D  AP   S +   P  
Sbjct: 223 DVPDDSSDDSDVPDDSSDDSEAPDDSSDDSEAPD-----DSSDDSEAPDDSSDDSEAPDD 277

Query: 310 ESLSSGSDGSSPLMSSAVQLNGSSSLTSEDP 340
            S  S +   S   S   + +  SS  SE P
Sbjct: 278 SSDDSEASDDS---SDDSEASDDSSDDSEAP 305



 Score = 32.7 bits (73), Expect = 0.82
 Identities = 26/89 (29%), Positives = 41/89 (46%), Gaps = 8/89 (8%)

Query: 238 PRERISDDIIIYDVTDD--NADEENIPVIPETNEDVISDPSNCS-----QYPDIVIVEDD 290
           P+ + S  ++I   +D+  +  EE    + E N D  S P  C      Q P IVI +DD
Sbjct: 69  PKRQASSVVVIDSDSDEECHTHEEKKAKLLEINSDDES-PECCHVKPAIQEPPIVISDDD 127

Query: 291 NEDEYAPVIQSGEQNEPARESLSSGSDGS 319
           N+D+    ++  + N    E+    SD S
Sbjct: 128 NDDDNGNDLEVPDDNSDDSEAPDDNSDDS 156



 Score = 31.6 bits (70), Expect = 1.8
 Identities = 27/104 (25%), Positives = 45/104 (43%), Gaps = 9/104 (8%)

Query: 221 TDNHHHKVPHSRTEGLKPRERISDDIIIYDVTDDNADEENIPVIPETNEDVISDPSNCSQ 280
           +D+   +  H +    +P   ISDD    D  DDN ++  +P     + +   D S+ S+
Sbjct: 102 SDDESPECCHVKPAIQEPPIVISDD----DNDDDNGNDLEVPDDNSDDSEAPDDNSDDSE 157

Query: 281 YP-----DIVIVEDDNEDEYAPVIQSGEQNEPARESLSSGSDGS 319
            P     D    +D+++D  AP   S + + P   S  S  D S
Sbjct: 158 APDDNSDDSEAPDDNSDDSEAPDDNSDDSDVPDDNSDDSSDDNS 201


>gi|239741304 PREDICTED: similar to Neuroblastoma breakpoint family
           member 6-like protein [Homo sapiens]
          Length = 298

 Score = 38.1 bits (87), Expect = 0.020
 Identities = 32/139 (23%), Positives = 63/139 (45%), Gaps = 6/139 (4%)

Query: 105 ENIKRKVSSSKPEENKIRQEDLTKIISSAQKVQIKQETIESRLSELKSENESLWKEVSEL 164
           E  K  + S   EE + ++ +L ++  SA +++I    I+++  EL      L ++  E 
Sbjct: 62  EECKDLIESVLEEEVQFQERELAELPRSAARLRIHDPLIQAQAEELTH----LRQKTQEG 117

Query: 165 RAKHAQQQQVIRKIVQFIVTLVQNNQLVSLKRKRPLLLNTNGAQKKNLFQHIVKEPTDNH 224
           R       Q ++  V+    L++N  +   +R+R       G+Q   +   + K  T+NH
Sbjct: 118 RGVCYLFTQHVKNTVKSFEGLLRNTDIAYYQRQRFCEQMVQGSQLTEIL--VRKLATENH 175

Query: 225 HHKVPHSRTEGLKPRERIS 243
           + K    R + L PR  ++
Sbjct: 176 NGKKNEDRQKPLAPRSELA 194


>gi|239741281 PREDICTED: Neuroblastoma breakpoint family member
           6-like protein [Homo sapiens]
          Length = 322

 Score = 38.1 bits (87), Expect = 0.020
 Identities = 32/139 (23%), Positives = 63/139 (45%), Gaps = 6/139 (4%)

Query: 105 ENIKRKVSSSKPEENKIRQEDLTKIISSAQKVQIKQETIESRLSELKSENESLWKEVSEL 164
           E  K  + S   EE + ++ +L ++  SA +++I    I+++  EL      L ++  E 
Sbjct: 62  EECKDLIESVLEEEVQFQERELAELPRSAARLRIHDPLIQAQAEELTH----LRQKTQEG 117

Query: 165 RAKHAQQQQVIRKIVQFIVTLVQNNQLVSLKRKRPLLLNTNGAQKKNLFQHIVKEPTDNH 224
           R       Q ++  V+    L++N  +   +R+R       G+Q   +   + K  T+NH
Sbjct: 118 RGVCYLFTQHVKNTVKSFEGLLRNTDIAYYQRQRFCEQMVQGSQLTEIL--VRKLATENH 175

Query: 225 HHKVPHSRTEGLKPRERIS 243
           + K    R + L PR  ++
Sbjct: 176 NGKKNEDRQKPLAPRSELA 194


>gi|112734867 retinitis pigmentosa GTPase regulator interacting
           protein 1 [Homo sapiens]
          Length = 1286

 Score = 38.1 bits (87), Expect = 0.020
 Identities = 53/247 (21%), Positives = 105/247 (42%), Gaps = 14/247 (5%)

Query: 83  QERDGPVEFQHPYFKQGQDDLLEN-IKRKVSSSKPE-ENKIRQEDLTKIISSAQKVQIKQ 140
           QER   +E +        D LLE+ +    SSS+P   N++  E L + +S  Q  Q+  
Sbjct: 361 QERVEDLEKERKLLNDNYDKLLESMLDSSDSSSQPHWSNELIAEQLQQQVSQLQD-QLDA 419

Query: 141 ETIESR-----LSELKSENESLWKEVSELRAKHAQQQQVIRKIVQFIVTLVQNNQLVSLK 195
           E  + R     LS  K++NE L  EV+ +  KH Q+ +    ++Q   T+ Q     S  
Sbjct: 420 ELEDKRKVLLELSREKAQNEDLKLEVTNILQKHKQEVE----LLQNAATISQPPDRQSEP 475

Query: 196 RKRPLLLNTNGAQKKNLFQHIVKEPTDNHHHKVPHSRTEGLKPRERISDDIIIYDVTDDN 255
              P +L  N   + +  ++  ++      +++  S  E     E+  D +I+    +  
Sbjct: 476 ATHPAVLQENTQIEPSEPKNQEEKKLSQVLNELQVSHAETTLELEKTRDMLILQRKINVC 535

Query: 256 ADEENIPVIPETNEDVISDPSNCSQYPDIVIVEDDNEDEYAPVIQSGEQNEPARESLSSG 315
             EE   ++ + + D         +   ++ ++++   +   +++S   + P  E L   
Sbjct: 536 YQEELEAMMTKADNDNRDHKEKLERLTRLLDLKNNRIKQLEGILRS--HDLPTSEQLKDV 593

Query: 316 SDGSSPL 322
           + G+ PL
Sbjct: 594 AYGTRPL 600



 Score = 29.3 bits (64), Expect = 9.1
 Identities = 70/340 (20%), Positives = 145/340 (42%), Gaps = 44/340 (12%)

Query: 102 DLLENIKRKVSSSKPEENKIRQEDLTKIISSAQKVQIKQETIESRLSE----LKSENESL 157
           +L  +IK KV   + ++  + + + + +++ AQ  ++ QE  E+ L +    L + +E+L
Sbjct: 265 ELRASIKEKVELIRLKK-LLHERNASLVMTKAQLTEV-QEAYETLLQKNQGILSAAHEAL 322

Query: 158 WKEVSELRA--KHAQQQQVIRKIVQFIVTLVQ------NNQLVSLKRKRPLLLNTNGAQK 209
            K+V+ELRA  K   ++ V  K     V+++Q        ++  L+++R LL   N    
Sbjct: 323 LKQVNELRAELKEESKKAVSLKSQLEDVSILQMTLKEFQERVEDLEKERKLL---NDNYD 379

Query: 210 KNLFQHIVKEPTDNHHHKVPHSRTEGLKPR-ERISDDI---------IIYDVTDDNADEE 259
           K L   +    + +  H       E L+ +  ++ D +         ++ +++ + A  E
Sbjct: 380 KLLESMLDSSDSSSQPHWSNELIAEQLQQQVSQLQDQLDAELEDKRKVLLELSREKAQNE 439

Query: 260 NIP-----VIPETNEDV--ISDPSNCSQYPDIVIVEDDNEDEYAPVIQSGEQNEPARESL 312
           ++      ++ +  ++V  + + +  SQ PD           +  V+Q   Q EP+ E  
Sbjct: 440 DLKLEVTNILQKHKQEVELLQNAATISQPPD----RQSEPATHPAVLQENTQIEPS-EPK 494

Query: 313 SSGSDGSSPLMSSAVQLNGSSSLTSEDPVTMMDSILNDNINLLGKVELLDYLDSIDCSLE 372
           +      S +++     +  ++L  E    M+  IL   IN+  + EL   +   D    
Sbjct: 495 NQEEKKLSQVLNELQVSHAETTLELEKTRDML--ILQRKINVCYQEELEAMMTKADNDNR 552

Query: 373 DFQAMLSGRQFSIDPDLLVDSENKGLETTKNNVVQPVSEE 412
           D +  L      +D   L ++  K LE    +   P SE+
Sbjct: 553 DHKEKLERLTRLLD---LKNNRIKQLEGILRSHDLPTSEQ 589


>gi|87299628 biorientation of chromosomes in cell division 1-like
           [Homo sapiens]
          Length = 3051

 Score = 37.7 bits (86), Expect = 0.025
 Identities = 37/181 (20%), Positives = 76/181 (41%), Gaps = 24/181 (13%)

Query: 95  YFKQGQDDLLENIKRKVSSSKPEENKIRQEDLTKIISSAQKVQIKQETIESRLSELKSEN 154
           Y+    D+L    +R+  + + EE  +R++   + +   +K + ++        + +S  
Sbjct: 480 YYSDSDDELTVEQRRQSIAKEKEERLLRRQINREKLEEKRKQKAEKTKSSKTKGQGRSSV 539

Query: 155 ESLWKEVSELRAKHAQQQQVI--RKIVQFIVTLVQNNQLVSLKRKRPLLLNTNGAQKKNL 212
           +        L  K A+ ++V+  RK+++  V L       S KRK+        ++KK  
Sbjct: 540 DLEESSTKSLEPKAARIKEVLKERKVLEKKVAL-------SKKRKKDSRNVEENSKKKQQ 592

Query: 213 FQHIVKEPTDNHHH------------KVPHSRTEGLKPRERISDDIIIYDVTDDNADEEN 260
           ++   KE      H            K  H+++E  KP  R+S+ +    V D+N +E  
Sbjct: 593 YEEDSKETLKTSEHCEKEKISSSKELKHVHAKSEPSKPARRLSESL---HVVDENKNESK 649

Query: 261 I 261
           +
Sbjct: 650 L 650


>gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo
            sapiens]
          Length = 1941

 Score = 37.7 bits (86), Expect = 0.025
 Identities = 24/77 (31%), Positives = 42/77 (54%), Gaps = 5/77 (6%)

Query: 100  QDDLLENIKRKVSSSKPEENKIRQEDLTKIISSAQKVQIKQE----TIESRLSELKSENE 155
            Q D L+ +K+K+   K  E K+  +DL   + +  K +   E    T+E +LSELKS+ E
Sbjct: 1212 QIDNLQRVKQKLEKEK-SEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEE 1270

Query: 156  SLWKEVSELRAKHAQQQ 172
               + +++L A+  + Q
Sbjct: 1271 EQQRLINDLTAQRGRLQ 1287


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.310    0.128    0.351 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,867,342
Number of Sequences: 37866
Number of extensions: 855466
Number of successful extensions: 4097
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 72
Number of HSP's successfully gapped in prelim test: 215
Number of HSP's that attempted gapping in prelim test: 3720
Number of HSP's gapped (non-prelim): 591
length of query: 518
length of database: 18,247,518
effective HSP length: 107
effective length of query: 411
effective length of database: 14,195,856
effective search space: 5834496816
effective search space used: 5834496816
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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