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Search of human proteins with 206597505
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|206597505 HIV-1 Rev binding protein isoform 1 [Homo sapiens]
(584 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|206597505 HIV-1 Rev binding protein isoform 1 [Homo sapiens] 1162 0.0
gi|206597507 HIV-1 Rev binding protein isoform 3 [Homo sapiens] 1099 0.0
gi|38570132 HIV-1 Rev binding protein isoform 2 [Homo sapiens] 1094 0.0
gi|206597509 HIV-1 Rev binding protein isoform 4 [Homo sapiens] 818 0.0
gi|91984781 ArfGAP with FG repeats 2 [Homo sapiens] 271 1e-72
gi|33946327 nucleoporin 214kDa [Homo sapiens] 75 2e-13
gi|113204622 stromal membrane-associated GTPase-activating prote... 72 1e-12
gi|21264558 stromal membrane-associated GTPase-activating protei... 71 3e-12
gi|23943872 small ArfGAP2 [Homo sapiens] 67 3e-11
gi|6806913 centaurin, alpha 1 [Homo sapiens] 66 1e-10
gi|161016767 mucin 21 [Homo sapiens] 65 1e-10
gi|8922652 ADP-ribosylation factor GTPase activating protein 1 i... 64 4e-10
gi|28416436 ADP-ribosylation factor GTPase activating protein 1 ... 63 7e-10
gi|80978934 centaurin, gamma 2 isoform 2 [Homo sapiens] 59 9e-09
gi|80978930 centaurin, gamma 2 isoform 1 [Homo sapiens] 59 9e-09
gi|24430146 nucleoporin 153kDa [Homo sapiens] 58 3e-08
gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens] 57 5e-08
gi|150378545 POM121 membrane glycoprotein (rat)-like [Homo sapiens] 56 1e-07
gi|239744074 PREDICTED: ArfGAP with GTPase domain, ankyrin repea... 55 1e-07
gi|239744064 PREDICTED: ArfGAP with GTPase domain, ankyrin repea... 55 1e-07
gi|117956373 ArfGAP with GTPase domain, ankyrin repeat and PH do... 55 1e-07
gi|110227613 centaurin, gamma 3 isoform a [Homo sapiens] 55 2e-07
gi|19111150 angiomotin isoform 2 [Homo sapiens] 54 3e-07
gi|166064029 angiomotin isoform 1 [Homo sapiens] 54 3e-07
gi|148806877 ankyrin repeat and GTPase domain Arf GTPase activat... 54 3e-07
gi|166851846 centaurin, gamma-like family, member 3 [Homo sapiens] 54 3e-07
gi|156104893 ArfGAP with GTPase domain, ankyrin repeat and PH do... 54 4e-07
gi|214829714 ADP-ribosylation factor GTPase activating protein 3... 53 9e-07
gi|117956371 ArfGAP with GTPase domain, ankyrin repeat and PH do... 53 9e-07
gi|167736355 mucin 4 isoform a [Homo sapiens] 52 2e-06
>gi|206597505 HIV-1 Rev binding protein isoform 1 [Homo sapiens]
Length = 584
Score = 1162 bits (3006), Expect = 0.0
Identities = 584/584 (100%), Positives = 584/584 (100%)
Query: 1 MAASAKRKQEEKHLKMLRDMTGLPHNRKCFDCDQRGPTYVNMTVGSFVCTSCSGSLRGLN 60
MAASAKRKQEEKHLKMLRDMTGLPHNRKCFDCDQRGPTYVNMTVGSFVCTSCSGSLRGLN
Sbjct: 1 MAASAKRKQEEKHLKMLRDMTGLPHNRKCFDCDQRGPTYVNMTVGSFVCTSCSGSLRGLN 60
Query: 61 PPHRVKSISMTTFTQQEIEFLQKHGNEVCKQIWLGLFDDRSSAIPDFRDPQKVKEFLQEK 120
PPHRVKSISMTTFTQQEIEFLQKHGNEVCKQIWLGLFDDRSSAIPDFRDPQKVKEFLQEK
Sbjct: 61 PPHRVKSISMTTFTQQEIEFLQKHGNEVCKQIWLGLFDDRSSAIPDFRDPQKVKEFLQEK 120
Query: 121 YEKKRWYVPPEQAKVVASVHASISGSSASSTSSTPEVKPLKSLLGDSAPTLHLNKGTPSQ 180
YEKKRWYVPPEQAKVVASVHASISGSSASSTSSTPEVKPLKSLLGDSAPTLHLNKGTPSQ
Sbjct: 121 YEKKRWYVPPEQAKVVASVHASISGSSASSTSSTPEVKPLKSLLGDSAPTLHLNKGTPSQ 180
Query: 181 SPVVGRSQGQQQEKKQFDLLSDLGSDIFAAPAPQSTATANFANFAHFNSHAAQNSANADF 240
SPVVGRSQGQQQEKKQFDLLSDLGSDIFAAPAPQSTATANFANFAHFNSHAAQNSANADF
Sbjct: 181 SPVVGRSQGQQQEKKQFDLLSDLGSDIFAAPAPQSTATANFANFAHFNSHAAQNSANADF 240
Query: 241 ANFDAFGQSSGSSNFGGFPTASHSPFQPQTTAFRMLSSSCSFGEFTSAFPLQATHSGSAA 300
ANFDAFGQSSGSSNFGGFPTASHSPFQPQTTAFRMLSSSCSFGEFTSAFPLQATHSGSAA
Sbjct: 241 ANFDAFGQSSGSSNFGGFPTASHSPFQPQTTAFRMLSSSCSFGEFTSAFPLQATHSGSAA 300
Query: 301 SVNANFAHFDNFPKSSSADFGTFNTSQSHQTASAVSKVSTNKAGLQTADKYAALANLDNI 360
SVNANFAHFDNFPKSSSADFGTFNTSQSHQTASAVSKVSTNKAGLQTADKYAALANLDNI
Sbjct: 301 SVNANFAHFDNFPKSSSADFGTFNTSQSHQTASAVSKVSTNKAGLQTADKYAALANLDNI 360
Query: 361 FSAGQGGDQGSGFGTTGKAPVGSVVSVPSQSSASSDKYAALAELDSVFSSAATSSNAYTS 420
FSAGQGGDQGSGFGTTGKAPVGSVVSVPSQSSASSDKYAALAELDSVFSSAATSSNAYTS
Sbjct: 361 FSAGQGGDQGSGFGTTGKAPVGSVVSVPSQSSASSDKYAALAELDSVFSSAATSSNAYTS 420
Query: 421 TSNASSNVFGTVPVVASAQTQPASSSVPAPFGATPSTNPFVAAAGPSVASSTNPFQTNAR 480
TSNASSNVFGTVPVVASAQTQPASSSVPAPFGATPSTNPFVAAAGPSVASSTNPFQTNAR
Sbjct: 421 TSNASSNVFGTVPVVASAQTQPASSSVPAPFGATPSTNPFVAAAGPSVASSTNPFQTNAR 480
Query: 481 GATAATFGTASMSMPTGFGTPAPYSLPTSFSGSFQQPAFPAQAAFPQQTAFSQQPNGFAA 540
GATAATFGTASMSMPTGFGTPAPYSLPTSFSGSFQQPAFPAQAAFPQQTAFSQQPNGFAA
Sbjct: 481 GATAATFGTASMSMPTGFGTPAPYSLPTSFSGSFQQPAFPAQAAFPQQTAFSQQPNGFAA 540
Query: 541 FGQTKPVVTPFGQVAAAGVSSNPFMTGAPTGQFPTGSSSTNPFL 584
FGQTKPVVTPFGQVAAAGVSSNPFMTGAPTGQFPTGSSSTNPFL
Sbjct: 541 FGQTKPVVTPFGQVAAAGVSSNPFMTGAPTGQFPTGSSSTNPFL 584
>gi|206597507 HIV-1 Rev binding protein isoform 3 [Homo sapiens]
Length = 560
Score = 1099 bits (2843), Expect = 0.0
Identities = 559/584 (95%), Positives = 559/584 (95%), Gaps = 24/584 (4%)
Query: 1 MAASAKRKQEEKHLKMLRDMTGLPHNRKCFDCDQRGPTYVNMTVGSFVCTSCSGSLRGLN 60
MAASAKRKQEEKHLKMLRDMTGLPHNRKCFDCDQRGPTYVNMTVGSFVCTSCSGSLRGLN
Sbjct: 1 MAASAKRKQEEKHLKMLRDMTGLPHNRKCFDCDQRGPTYVNMTVGSFVCTSCSGSLRGLN 60
Query: 61 PPHRVKSISMTTFTQQEIEFLQKHGNEVCKQIWLGLFDDRSSAIPDFRDPQKVKEFLQEK 120
PPHRVKSISMTTFTQQEIEFLQKHGNEVCKQIWLGLFDDRSSAIPDFRDPQKVKEFLQEK
Sbjct: 61 PPHRVKSISMTTFTQQEIEFLQKHGNEVCKQIWLGLFDDRSSAIPDFRDPQKVKEFLQEK 120
Query: 121 YEKKRWYVPPEQAKVVASVHASISGSSASSTSSTPEVKPLKSLLGDSAPTLHLNKGTPSQ 180
YEKKRWYVPPEQAKVVASVHASISGSSASSTSSTPEVKPLKSLLGDSAPTLHLNKGTPSQ
Sbjct: 121 YEKKRWYVPPEQAKVVASVHASISGSSASSTSSTPEVKPLKSLLGDSAPTLHLNKGTPSQ 180
Query: 181 SPVVGRSQGQQQEKKQFDLLSDLGSDIFAAPAPQSTATANFANFAHFNSHAAQNSANADF 240
SPVVGRSQGQQQEKKQFDLLSDLGSDIFAAPAPQSTATANFANFAHFNSHAAQNSANADF
Sbjct: 181 SPVVGRSQGQQQEKKQFDLLSDLGSDIFAAPAPQSTATANFANFAHFNSHAAQNSANADF 240
Query: 241 ANFDAFGQSSGSSNFGGFPTASHSPFQPQTTAFRMLSSSCSFGEFTSAFPLQATHSGSAA 300
ANFDAFGQSSGSSNFGGFPTASHSPFQPQTT GSAA
Sbjct: 241 ANFDAFGQSSGSSNFGGFPTASHSPFQPQTTG------------------------GSAA 276
Query: 301 SVNANFAHFDNFPKSSSADFGTFNTSQSHQTASAVSKVSTNKAGLQTADKYAALANLDNI 360
SVNANFAHFDNFPKSSSADFGTFNTSQSHQTASAVSKVSTNKAGLQTADKYAALANLDNI
Sbjct: 277 SVNANFAHFDNFPKSSSADFGTFNTSQSHQTASAVSKVSTNKAGLQTADKYAALANLDNI 336
Query: 361 FSAGQGGDQGSGFGTTGKAPVGSVVSVPSQSSASSDKYAALAELDSVFSSAATSSNAYTS 420
FSAGQGGDQGSGFGTTGKAPVGSVVSVPSQSSASSDKYAALAELDSVFSSAATSSNAYTS
Sbjct: 337 FSAGQGGDQGSGFGTTGKAPVGSVVSVPSQSSASSDKYAALAELDSVFSSAATSSNAYTS 396
Query: 421 TSNASSNVFGTVPVVASAQTQPASSSVPAPFGATPSTNPFVAAAGPSVASSTNPFQTNAR 480
TSNASSNVFGTVPVVASAQTQPASSSVPAPFGATPSTNPFVAAAGPSVASSTNPFQTNAR
Sbjct: 397 TSNASSNVFGTVPVVASAQTQPASSSVPAPFGATPSTNPFVAAAGPSVASSTNPFQTNAR 456
Query: 481 GATAATFGTASMSMPTGFGTPAPYSLPTSFSGSFQQPAFPAQAAFPQQTAFSQQPNGFAA 540
GATAATFGTASMSMPTGFGTPAPYSLPTSFSGSFQQPAFPAQAAFPQQTAFSQQPNGFAA
Sbjct: 457 GATAATFGTASMSMPTGFGTPAPYSLPTSFSGSFQQPAFPAQAAFPQQTAFSQQPNGFAA 516
Query: 541 FGQTKPVVTPFGQVAAAGVSSNPFMTGAPTGQFPTGSSSTNPFL 584
FGQTKPVVTPFGQVAAAGVSSNPFMTGAPTGQFPTGSSSTNPFL
Sbjct: 517 FGQTKPVVTPFGQVAAAGVSSNPFMTGAPTGQFPTGSSSTNPFL 560
>gi|38570132 HIV-1 Rev binding protein isoform 2 [Homo sapiens]
Length = 562
Score = 1094 bits (2830), Expect = 0.0
Identities = 559/586 (95%), Positives = 559/586 (95%), Gaps = 26/586 (4%)
Query: 1 MAASAKRKQEEKHLKMLRDMTGLPHNRKCFDCDQRGPTYVNMTVGSFVCTSCSGSLRGLN 60
MAASAKRKQEEKHLKMLRDMTGLPHNRKCFDCDQRGPTYVNMTVGSFVCTSCSGSLRGLN
Sbjct: 1 MAASAKRKQEEKHLKMLRDMTGLPHNRKCFDCDQRGPTYVNMTVGSFVCTSCSGSLRGLN 60
Query: 61 PPHRVKSISMTTFTQQEIEFLQKHGNEVCKQIWLGLFDDRSSAIPDFRDPQKVKEFLQEK 120
PPHRVKSISMTTFTQQEIEFLQKHGNEVCKQIWLGLFDDRSSAIPDFRDPQKVKEFLQEK
Sbjct: 61 PPHRVKSISMTTFTQQEIEFLQKHGNEVCKQIWLGLFDDRSSAIPDFRDPQKVKEFLQEK 120
Query: 121 YEKKRWYVPPEQAKVVASVHASISGSSASSTSSTPEVKPLKSLLGDSAPTLHLNKGTPSQ 180
YEKKRWYVPPEQAKVVASVHASISGSSASSTSSTPEVKPLKSLLGDSAPTLHLNKGTPSQ
Sbjct: 121 YEKKRWYVPPEQAKVVASVHASISGSSASSTSSTPEVKPLKSLLGDSAPTLHLNKGTPSQ 180
Query: 181 SPVVGRSQGQQQEKKQFDLLSDLGSDIFAAPAPQSTATANFANFAHFNSHAAQNSANADF 240
SPVVGRSQGQQQEKKQFDLLSDLGSDIFAAPAPQSTATANFANFAHFNSHAAQNSANADF
Sbjct: 181 SPVVGRSQGQQQEKKQFDLLSDLGSDIFAAPAPQSTATANFANFAHFNSHAAQNSANADF 240
Query: 241 ANFDAFGQSSGSSNFGGFPTASHSPFQPQTTAFRMLSSSCSFGEFTSAFPLQATHSGSAA 300
ANFDAFGQSSGSSNFGGFPTASHSPFQPQTT GSAA
Sbjct: 241 ANFDAFGQSSGSSNFGGFPTASHSPFQPQTT------------------------GGSAA 276
Query: 301 SVNANFAHFDNFPKSSSADFGTFNTSQSHQTASAVSKVSTNKAGLQTADKYAALANLDNI 360
SVNANFAHFDNFPKSSSADFGTFNTSQSHQTASAVSKVSTNKAGLQTADKYAALANLDNI
Sbjct: 277 SVNANFAHFDNFPKSSSADFGTFNTSQSHQTASAVSKVSTNKAGLQTADKYAALANLDNI 336
Query: 361 FSAGQGGDQGSGFGTTGKAPVGSVVSVPSQSSASSDKYAALAELDSVFSSAATSSNAYTS 420
FSAGQGGDQGSGFGTTGKAPVGSVVSVPSQSSASSDKYAALAELDSVFSSAATSSNAYTS
Sbjct: 337 FSAGQGGDQGSGFGTTGKAPVGSVVSVPSQSSASSDKYAALAELDSVFSSAATSSNAYTS 396
Query: 421 TSNASSNVFGTVPVVASAQTQPASSSVPAPFGATPSTNPFVAAAGPSVASSTNPFQTNAR 480
TSNASSNVFGTVPVVASAQTQPASSSVPAPFGATPSTNPFVAAAGPSVASSTNPFQTNAR
Sbjct: 397 TSNASSNVFGTVPVVASAQTQPASSSVPAPFGATPSTNPFVAAAGPSVASSTNPFQTNAR 456
Query: 481 GATAATFGTASMSMPTGFGTPAPYSLPTSFSGSFQQPAFPAQAAFPQQTAFSQQPN--GF 538
GATAATFGTASMSMPTGFGTPAPYSLPTSFSGSFQQPAFPAQAAFPQQTAFSQQPN GF
Sbjct: 457 GATAATFGTASMSMPTGFGTPAPYSLPTSFSGSFQQPAFPAQAAFPQQTAFSQQPNGAGF 516
Query: 539 AAFGQTKPVVTPFGQVAAAGVSSNPFMTGAPTGQFPTGSSSTNPFL 584
AAFGQTKPVVTPFGQVAAAGVSSNPFMTGAPTGQFPTGSSSTNPFL
Sbjct: 517 AAFGQTKPVVTPFGQVAAAGVSSNPFMTGAPTGQFPTGSSSTNPFL 562
>gi|206597509 HIV-1 Rev binding protein isoform 4 [Homo sapiens]
Length = 522
Score = 818 bits (2114), Expect = 0.0
Identities = 452/590 (76%), Positives = 472/590 (80%), Gaps = 74/590 (12%)
Query: 1 MAASAKRKQEEKHLKMLRDMTGLPHNRKCFDCDQRGPTYVNMTVGSFVCTSCSGSLRGLN 60
MAASAKRKQEEKHLKMLRDMTGLPHNRKCFDCDQRGPTYVNMTVGSFVCTSCSGSLRGLN
Sbjct: 1 MAASAKRKQEEKHLKMLRDMTGLPHNRKCFDCDQRGPTYVNMTVGSFVCTSCSGSLRGLN 60
Query: 61 PPHRVKSISMTTFTQQEIEFLQKHGNEVCKQIWLGLFDDRSSAIPDFRDPQKVKEFLQEK 120
PPHRVKSISMTTFTQQEIEFLQKHGNEVCKQIWLGLFDDRSSAIPDFRDPQKVKEFLQEK
Sbjct: 61 PPHRVKSISMTTFTQQEIEFLQKHGNEVCKQIWLGLFDDRSSAIPDFRDPQKVKEFLQEK 120
Query: 121 YEKKRWYVPPEQAKVVASVHASISGSSASSTSSTPEVKPLKSLLGDSAPTLHLNKGTPSQ 180
YEKKRWYVPPEQAKVVASVHASISGSSASSTSSTPEVKPLKSLLGDSAPTLHLNKGTPSQ
Sbjct: 121 YEKKRWYVPPEQAKVVASVHASISGSSASSTSSTPEVKPLKSLLGDSAPTLHLNKGTPSQ 180
Query: 181 SPVVGRSQGQQQEKKQFDLLSDLGSDIFAAPAPQSTATANFANFAHFNSHAAQNSA--NA 238
SPVVGRSQGQQQEKKQFDLLSDLGSDIFAAPAPQSTATANFANFAHFNSHA ++A NA
Sbjct: 181 SPVVGRSQGQQQEKKQFDLLSDLGSDIFAAPAPQSTATANFANFAHFNSHAGGSAASVNA 240
Query: 239 DFANFDAFGQSSGSSNFGGFPTASHSPFQPQTTAFRMLSSSCSFGEFTSAFPLQATHSGS 298
+FA+FD F +SS S++FG F T+ Q TA + S T+ LQ
Sbjct: 241 NFAHFDNFPKSS-SADFGTFNTS-----QSHQTASAVSKVS------TNKAGLQ------ 282
Query: 299 AASVNANFAHFDN-FPKSSSADFGT-FNTSQSHQTASAVSKVSTNKAGLQTADKYAALAN 356
A A A+ DN F D G+ F T+ S VS S + A ++DKYAALA
Sbjct: 283 TADKYAALANLDNIFSAGQGGDQGSGFGTTGKAPVGSVVSVPSQSSA---SSDKYAALAE 339
Query: 357 LDNIFSAGQGGDQGSGFGTTGKAPVGSVVSVPSQSSASSDKYAALAELDSVFSSAATSSN 416
LD++FS S+A+S SN
Sbjct: 340 LDSVFS----------------------------SAATS-------------------SN 352
Query: 417 AYTSTSNASSNVFGTVPVVASAQTQPASSSVPAPFGATPSTNPFVAAAGPSVASSTNPFQ 476
AYTSTSNASSNVFGTVPVVASAQTQPASSSVPAPFGATPSTNPFVAAAGPSVASSTNPFQ
Sbjct: 353 AYTSTSNASSNVFGTVPVVASAQTQPASSSVPAPFGATPSTNPFVAAAGPSVASSTNPFQ 412
Query: 477 TNARGATAATFGTASMSMPTGFGTPAPYSLPTSFSGSFQQPAFPAQAAFPQQTAFSQQPN 536
TNARGATAATFGTASMSMPTGFGTPAPYSLPTSFSGSFQQPAFPAQAAFPQQTAFSQQPN
Sbjct: 413 TNARGATAATFGTASMSMPTGFGTPAPYSLPTSFSGSFQQPAFPAQAAFPQQTAFSQQPN 472
Query: 537 --GFAAFGQTKPVVTPFGQVAAAGVSSNPFMTGAPTGQFPTGSSSTNPFL 584
GFAAFGQTKPVVTPFGQVAAAGVSSNPFMTGAPTGQFPTGSSSTNPFL
Sbjct: 473 GAGFAAFGQTKPVVTPFGQVAAAGVSSNPFMTGAPTGQFPTGSSSTNPFL 522
>gi|91984781 ArfGAP with FG repeats 2 [Homo sapiens]
Length = 481
Score = 271 bits (693), Expect = 1e-72
Identities = 209/561 (37%), Positives = 252/561 (44%), Gaps = 125/561 (22%)
Query: 26 NRKCFDCDQRGPTYVNMTVGSFVCTSCSGSLRGLNPPHRVKSISMTTFTQQEIEFLQKHG 85
NR CF+C QRG TYV++TVGSFVCT+CSG LRGLNPPHRVKSISMTTFT+ E+ FLQ G
Sbjct: 44 NRHCFECAQRGVTYVDITVGSFVCTTCSGLLRGLNPPHRVKSISMTTFTEPEVVFLQSRG 103
Query: 86 NEVCKQIWLGLFDDRSSAIPDFRDPQKVKEFLQEKYEKKRWYVPPEQAKVVASVHASISG 145
NEVC++IWLGLFD R+S +PD RDPQKVKEFLQEKYEKKRWYVPP+Q K S
Sbjct: 104 NEVCRKIWLGLFDARTSLVPDSRDPQKVKEFLQEKYEKKRWYVPPDQVKGPTYTKGS--- 160
Query: 146 SSASSTSSTPEVKPLKSLLGDSAPTLHLNKGTPSQSPVVGRSQGQQQEKKQFDLLSDLGS 205
+S S PE KPL++LLGD AP+L + T SQ
Sbjct: 161 ASTPVQGSIPEGKPLRTLLGDPAPSLSVAASTSSQ------------------------- 195
Query: 206 DIFAAPAPQSTATANFANFAHFNSHAAQNSANADFANFDAFGQSSGSSNFGGFPTASHSP 265
P QS A + A H++ A+ D ++ GG P A+
Sbjct: 196 -----PVSQSHARTSQARSTQPPPHSSVKKASTDLL-----------ADIGGDPFAA--- 236
Query: 266 FQPQTTAFRMLSSSCSFGEFTSAFPLQATHSGSAASVNANFAHFDNFPKS-SSADFGTFN 324
PQ M + +F F P Q FA+FD F SS+ FG+
Sbjct: 237 --PQ-----MAPAFAAFPAFGGQTPSQG-----------GFANFDAFSSGPSSSVFGSLP 278
Query: 325 TSQSHQTASAVSKVSTNKAGLQTADKYAALANLDNIFSAGQGGDQGSGFGTTGKAPVGSV 384
+ +A Q A G QG+ FG T AP
Sbjct: 279 PA--------------GQASFQAQPTPA-------------GSSQGTPFGATPLAPASQP 311
Query: 385 VSVPSQSSASSDKYAALAELDSVFSSAATSSNAYTSTSNASSNVFGTVPVVASAQTQPAS 444
S+ S A S+F A G VP + S
Sbjct: 312 NSLADVGSFLGPGVPAAGVPSSLFGMA------------------GQVPPLQSVTMGGGG 353
Query: 445 -SSVPAPFGATPSTNPFVAAAGPSVASSTNPFQTNARGATAATFGTASMSMPTGFGTPAP 503
SS FGA TNPF A A S STNPFQ N A FG +S G G P
Sbjct: 354 GSSTGLAFGAF--TNPFTAPAAQSPLPSTNPFQPNGL-APGPGFGMSS----AGPGFPQA 406
Query: 504 YSLPTSFSGSFQQPAFPAQAAFPQQTAFSQQPNGFAAFGQTKPVVTPFGQVAAAGVSSNP 563
+F+ SF P FP Q QQ Q + F G K P Q AG+S+NP
Sbjct: 407 VPPTGAFASSFPAPLFPPQTPLVQQ----QNGSSFGDLGSAKLGQRPLSQ--PAGISTNP 460
Query: 564 FMTGAPTGQFPTGSSSTNPFL 584
FMTG + F + +TNPFL
Sbjct: 461 FMTGPSSSPFASKPPTTNPFL 481
>gi|33946327 nucleoporin 214kDa [Homo sapiens]
Length = 2090
Score = 75.1 bits (183), Expect = 2e-13
Identities = 109/438 (24%), Positives = 161/438 (36%), Gaps = 67/438 (15%)
Query: 130 PEQAKVVASVHASISGSSASSTSSTPEVKPLKSLLGDSAPTLH------LNKGTPSQSPV 183
P +V AS S+ G ST+ST P S G S+P + T Q+ V
Sbjct: 1672 PVFGQVAASTAPSLFGQQTGSTASTAAATPQVSSSGFSSPAFGTTAPGVFGQTTFGQASV 1731
Query: 184 VGRSQGQQQEKKQFDLLSDLGSDIFAAPAPQSTATANFANFAHFNSHAAQNSANADFANF 243
G+S F F PA + + + + F A+ S+++ F+
Sbjct: 1732 FGQSASSAASVFSFSQPGFSSVPAFGQPASSTPTSTSGSVFGA----ASSTSSSSSFS-- 1785
Query: 244 DAFGQSSGSSNFGGFPTASHSPFQPQTTAFRMLSSSCSFGEFTSAFPLQATHSGSAASVN 303
FGQSS ++ G F ++ F S FG+ S F + + +AA+
Sbjct: 1786 --FGQSSPNTGGGLFGQSNAPAF----------GQSPGFGQGGSVFGGTSAATTTAATSG 1833
Query: 304 ANFAHFDNFPKSSSAD-FG--------TFNTSQSHQTASAVSKVSTNKAG---LQTADKY 351
+F F S++ FG F S + S +T + G K
Sbjct: 1834 FSFCQASGFGSSNTGSVFGQAASTGGIVFGQQSSSSSGSVFGSGNTGRGGGFFSGLGGKP 1893
Query: 352 AALANLDNIFSAGQGGDQGSGFGTTGKAPVGSVVSVPSQSSASSDKYAALAELD--SVFS 409
+ A N FS+ GG FG+T + ++ + ++ E FS
Sbjct: 1894 SQDAANKNPFSSASGG-----FGSTATSNTSNLFGNSGAKTFGGFASSSFGEQKPTGTFS 1948
Query: 410 SAATS--SNAYTSTSNASSNVFGTVPVVASAQT---QPASSSVPAPFGATPSTNPFVAAA 464
S S S + +S + FG PV S T P VPA FG+ P+ + +
Sbjct: 1949 SGGGSVASQGFGFSSPNKTGGFGAAPVFGSPPTFGGSPGFGGVPA-FGSAPAFTSPLGST 2007
Query: 465 GPSVASSTNPFQTNARGATAATFGTASMSMPTGFGTPAPYSLPTSFSGSFQQPAFPAQAA 524
G V F A+A FG S S T FGT A + PT GS Q
Sbjct: 2008 GGKV------FGEGTAAASAGGFGFGSSSNTTSFGTLASQNAPT--FGSLSQ-------- 2051
Query: 525 FPQQTAFSQQPNGFAAFG 542
Q + F Q +GF+ FG
Sbjct: 2052 --QTSGFGTQSSGFSGFG 2067
Score = 57.8 bits (138), Expect = 3e-08
Identities = 103/418 (24%), Positives = 162/418 (38%), Gaps = 57/418 (13%)
Query: 142 SISGSSASSTSSTPEVKPLKSLLGDSAPTLHLNKGTPSQSPVVGRSQGQQQEKKQFDLLS 201
S++ +A+STSST L S+ + GT + S G QQ
Sbjct: 1396 SVAPPAATSTSSTAVFGSLPVTSAGSSGVISFG-GTSLSAGKTSFSFGSQQTNSTVPP-- 1452
Query: 202 DLGSDIFAAPAPQSTATANFANFAHFNSHAAQNSANADFANFDAFGQSSGSSNFGGFP-- 259
+AP P + AT +F + + +SA A G+S+ + P
Sbjct: 1453 -------SAPPPTTAATPLPTSFPTLSFGSLLSSATTPSLPMSA-GRSTEEATSSALPEK 1504
Query: 260 ------TASHSPFQPQTTAFRMLSSSCSFGEFTSAFPLQA----THSGSAASVNANFAHF 309
+AS + + + ++ + + P+ A ++SG+AAS + A
Sbjct: 1505 PGDSEVSASAASLLEEQQSAQLPQAPPQTSDSVKKEPVLAQPAVSNSGTAASSTSLVA-- 1562
Query: 310 DNFPKSSSADFGTFNTSQSHQTASAVSKVSTNKAGLQTADKYAALANLDNIFSAGQGGDQ 369
SA+ T AV S+ QTA AA++ SAG +
Sbjct: 1563 ------LSAEATPATTGVPDARTEAVPPASSFSVPGQTAVTAAAIS------SAGPVAVE 1610
Query: 370 GSGFGTTGKAPVGSVVS--VPSQSSASSDKYAALAELDSVFSS--AATSSNAYTSTSNAS 425
T P+ S + V SA + + + SVF+ AA+SS+A+ +N +
Sbjct: 1611 ------TSSTPIASSTTSIVAPGPSAEAAAFGTVTSGSSVFAQPPAASSSSAFNQLTNNT 1664
Query: 426 SNVFGTVPVVASAQTQPASSSVPAPFGATPSTNPFVAAAGPSVASSTNPFQTNARGATA- 484
+ PV Q A+S+ P+ FG + AAA P V+SS F + A G TA
Sbjct: 1665 ATAPSATPVFG----QVAASTAPSLFGQQTGSTASTAAATPQVSSS--GFSSPAFGTTAP 1718
Query: 485 ATFGTASMSMPTGFGTPAPYSLPTSFSGSFQQPAFPAQAAFPQQTAFSQQPNGFAAFG 542
FG + + FG A S + F SF QP F + AF Q + + + FG
Sbjct: 1719 GVFGQTTFGQASVFGQSAS-SAASVF--SFSQPGFSSVPAFGQPASSTPTSTSGSVFG 1773
Score = 51.6 bits (122), Expect = 2e-06
Identities = 115/484 (23%), Positives = 184/484 (38%), Gaps = 56/484 (11%)
Query: 138 SVHASISGSSASSTSSTPEVKPLKSLLGDSAPTLHLNKGTPSQSPVVGRSQGQQQEKKQF 197
S+ S S+ +TSS KP S + SA +L L + +Q P +K+
Sbjct: 1484 SLPMSAGRSTEEATSSALPEKPGDSEVSASAASL-LEEQQSAQLPQAPPQTSDSVKKEPV 1542
Query: 198 DLLSDLGSDIFAAPAPQSTATANFANFAHFNSHAAQNSANADFANFDAFGQSSGSSNFGG 257
+ + AA + A + A A A+ A ++F GQ++ ++
Sbjct: 1543 LAQPAVSNSGTAASSTSLVALSAEATPATTGVPDARTEAVPPASSFSVPGQTAVTAA--- 1599
Query: 258 FPTASHSPFQPQTTAFRMLSSSCSFGEFTSAFPLQATHSGSAASVNANFAHFDNFPKSSS 317
+S P +T++ + SS+ S +A G+ S ++ FA SS+
Sbjct: 1600 -AISSAGPVAVETSSTPIASSTTSI--VAPGPSAEAAAFGTVTSGSSVFAQPPAASSSSA 1656
Query: 318 ADFGTFNTSQSHQTASAVSKVSTNKA----GLQTADKYAALANLDNIFSAGQGGDQGSGF 373
+ T NT+ + +V+ + A G QT + A + S+G F
Sbjct: 1657 FNQLTNNTATAPSATPVFGQVAASTAPSLFGQQTGSTASTAAATPQVSSSGFSSP---AF 1713
Query: 374 GTTGKAPVG------------SVVSVPSQSSASSDKYAALAELDSVFSSAATSSN----- 416
GTT G S S S S S ++++ SS TS++
Sbjct: 1714 GTTAPGVFGQTTFGQASVFGQSASSAASVFSFSQPGFSSVPAFGQPASSTPTSTSGSVFG 1773
Query: 417 AYTSTSNASSNVFG-----TVPVVASAQTQPASSSVP------APFGATPSTNPFVAAAG 465
A +STS++SS FG T + PA P + FG T + A +G
Sbjct: 1774 AASSTSSSSSFSFGQSSPNTGGGLFGQSNAPAFGQSPGFGQGGSVFGGTSAATTTAATSG 1833
Query: 466 PSVASSTNPFQTNARGATAATFGTASMSMPTGFGTPAPYSLPTSF-SGSFQQPA--FPAQ 522
S ++ +N T + FG A+ + FG + S + F SG+ + F
Sbjct: 1834 FSFCQASGFGSSN----TGSVFGQAASTGGIVFGQQSSSSSGSVFGSGNTGRGGGFFSGL 1889
Query: 523 AAFPQQTAFSQQPNGFAA--FGQTKPVVTP--FGQVAA---AGVSSNPFMTGAPTGQFPT 575
P Q A ++ P A+ FG T T FG A G +S+ F PTG F +
Sbjct: 1890 GGKPSQDAANKNPFSSASGGFGSTATSNTSNLFGNSGAKTFGGFASSSFGEQKPTGTFSS 1949
Query: 576 GSSS 579
G S
Sbjct: 1950 GGGS 1953
Score = 40.4 bits (93), Expect = 0.005
Identities = 97/425 (22%), Positives = 153/425 (36%), Gaps = 55/425 (12%)
Query: 136 VASVHASISGSSASSTSSTPEVKPLKSLLGDSA-PTLHLNKGTP---SQSPVVGRSQGQQ 191
+AS +++ + S+ + P+V ++ L + A P+ + P +++P +
Sbjct: 1101 MASQAPAVNTLTESTLKNVPQVVNVQELKNNPATPSTAMGSSVPYSTAKTPHPVLTPVAA 1160
Query: 192 QEKKQFDLLSDLGSDIFAAPAPQSTATANFANFAHFNSHAAQN-SANADFANFDAFGQSS 250
+ KQ L++ L + Q ++ + A + SA+ F+ +F S
Sbjct: 1161 NQAKQGSLINSLKPSGPTPASGQLSSGDKASGTAKIETAVTSTPSASGQFSKPFSFSPSG 1220
Query: 251 GSSNFGGFPTASHSPFQPQTTAFRMLSSSCSFGEFTSAFPLQATHSGSAASVNA--NFAH 308
NFG S F A S F+S GS S A +
Sbjct: 1221 TGFNFGIITPTPSSNFTAAQGATPSTKESSQPDAFSSG-------GGSKPSYEAIPESSP 1273
Query: 309 FDNFPKSSSADFGTFNTSQSHQTASAVSKVSTNKAGLQTA-DKYAALANLDNI------- 360
+S+ G S S A + + +ST + L+T K L ++
Sbjct: 1274 PSGITSASNTTPGEPAASSSRPVAPSGTALSTTSSKLETPPSKLGELLFPSSLAGETLGS 1333
Query: 361 FSAGQGGDQGSGFGTTGKAPVGSVVS--------VPSQSSASSDKYAALAELDSVFSSAA 412
FS + G T KA S+ S VPS + ++ V SSA
Sbjct: 1334 FSGLRVGQADDSTKPTNKASSTSLTSTQPTKTSGVPSGFNFTAPPVLGKHTEPPVTSSAT 1393
Query: 413 TSSNAY-TSTSNASSNVFGTVPVVASAQTQPASSSVPAPFGATPSTNPFVAAAGPSVASS 471
T+S A +TS +S+ VFG++PV T SS V + G + S + G +S
Sbjct: 1394 TTSVAPPAATSTSSTAVFGSLPV-----TSAGSSGVISFGGTSLSAGKTSFSFGSQQTNS 1448
Query: 472 TNPFQTNARGATAATFGTASMSMPTGFGTPAPYSLPT----SFSGSFQQPAFPAQAAFPQ 527
T P S PT TP P S PT S S P+ P A
Sbjct: 1449 TVP---------------PSAPPPTTAATPLPTSFPTLSFGSLLSSATTPSLPMSAGRST 1493
Query: 528 QTAFS 532
+ A S
Sbjct: 1494 EEATS 1498
Score = 38.1 bits (87), Expect = 0.023
Identities = 68/275 (24%), Positives = 102/275 (37%), Gaps = 31/275 (11%)
Query: 256 GGFPTASHSPFQPQTTAFRMLSSSCSFGEFTSAFPLQATHSGSAASVNANFAHFDNFPKS 315
G PT S PQ ++ S + A P+ A F+ + KS
Sbjct: 432 GSTPTTPTSSQAPQKLDASAAAAPASLPPSSPAAPIATFSLLPAGGAPTVFSFGSSSLKS 491
Query: 316 SSADFGT----FNTSQSHQTA-----SAVSKVSTNKAGLQTADKYAALANLDNIFSAGQG 366
S+ G + S S + A S S V +KA L + +A FS G
Sbjct: 492 SATVTGEPPSYSSGSDSSKAAPGPGPSTFSFVPPSKASLAPTPAASPVAPSAASFSFGSS 551
Query: 367 GDQGSGFGTTGKAPVGSVVSVPSQSSASSDKYAALAELDSVFSSAATSSNAYTSTSNASS 426
G + + T P S ++ + S A L F++AATS+ +S S
Sbjct: 552 GFKPTLESTP--VPSVSAPNIAMKPSFPPSTSAVKVNLSEKFTAAATSTPVSSSQSAPPM 609
Query: 427 NVFGTVPVVASAQTQPASS---SVPAPFGATPSTNPFVAAAGPSVASSTNPFQTNARGAT 483
+ F S+ ++PA+S S P P A PS+ P ++ PS + R A
Sbjct: 610 SPF-------SSASKPAASGPLSHPTPLSAPPSSVPLKSSVLPS---------PSGRSAQ 653
Query: 484 AATFGTASMSMPTGFGTPAPYSLPTSFSGSFQQPA 518
++ SM + TP P + P S QPA
Sbjct: 654 GSSSPVPSMVQKSPRITP-PAAKPGSPQAKSLQPA 687
Score = 30.8 bits (68), Expect = 3.6
Identities = 38/142 (26%), Positives = 57/142 (40%), Gaps = 19/142 (13%)
Query: 410 SAATSSNAYTSTSNASSNVFGTVPVVASAQTQPASSSVPAPFGATPSTNPFVA---AAGP 466
S A S+ ST+ V PV A+ Q + + P G TP++ + A+G
Sbjct: 1136 STAMGSSVPYSTAKTPHPVL--TPVAANQAKQGSLINSLKPSGPTPASGQLSSGDKASGT 1193
Query: 467 SVASSTNPFQTNARGATAATFGTASMSMPTGFG--TPAPYSLPTSFSGSFQQPAFPAQAA 524
+ + +A G + F + FG TP P S T+ AQ A
Sbjct: 1194 AKIETAVTSTPSASGQFSKPFSFSPSGTGFNFGIITPTPSSNFTA-----------AQGA 1242
Query: 525 FPQQTAFSQQPNGFAAFGQTKP 546
P T S QP+ F++ G +KP
Sbjct: 1243 TPS-TKESSQPDAFSSGGGSKP 1263
>gi|113204622 stromal membrane-associated GTPase-activating protein
1 isoform A [Homo sapiens]
Length = 467
Score = 72.0 bits (175), Expect = 1e-12
Identities = 43/156 (27%), Positives = 81/156 (51%), Gaps = 14/156 (8%)
Query: 7 RKQEEKHLKMLRDMTGLPHNRKCFDCDQRGPTYVNMTVGSFVCTSCSGSLRGLNPP-HRV 65
+K E+H +L + N+ C DC+ +GP + + +G F+C C+G R L RV
Sbjct: 11 QKLNEQHQLILSKLLREEDNKYCADCEAKGPRWASWNIGVFICIRCAGIHRNLGVHISRV 70
Query: 66 KSISMTTFTQQEIEFLQKHGNEVCKQIWLGLFDDRSSAIPDFRDP---QKVKEFLQEKYE 122
KS+++ +T ++I+ +Q GN + ++ ++ +FR P Q V+ F+++KYE
Sbjct: 71 KSVNLDQWTAEQIQCMQDMGNTKARLLY------EANLPENFRRPQTDQAVEFFIRDKYE 124
Query: 123 KKRWYVPPEQAKVVASVHASISGSSASSTSSTPEVK 158
KK++Y +A + S S + S+P ++
Sbjct: 125 KKKYY----DKNAIAITNISSSDAPLQPLVSSPSLQ 156
>gi|21264558 stromal membrane-associated GTPase-activating protein 1
isoform B [Homo sapiens]
Length = 440
Score = 70.9 bits (172), Expect = 3e-12
Identities = 38/125 (30%), Positives = 70/125 (56%), Gaps = 10/125 (8%)
Query: 7 RKQEEKHLKMLRDMTGLPHNRKCFDCDQRGPTYVNMTVGSFVCTSCSGSLRGLNPP-HRV 65
+K E+H +L + N+ C DC+ +GP + + +G F+C C+G R L RV
Sbjct: 11 QKLNEQHQLILSKLLREEDNKYCADCEAKGPRWASWNIGVFICIRCAGIHRNLGVHISRV 70
Query: 66 KSISMTTFTQQEIEFLQKHGNEVCKQIWLGLFDDRSSAIPDFRDP---QKVKEFLQEKYE 122
KS+++ +T ++I+ +Q GN + ++ ++ +FR P Q V+ F+++KYE
Sbjct: 71 KSVNLDQWTAEQIQCMQDMGNTKARLLY------EANLPENFRRPQTDQAVEFFIRDKYE 124
Query: 123 KKRWY 127
KK++Y
Sbjct: 125 KKKYY 129
>gi|23943872 small ArfGAP2 [Homo sapiens]
Length = 429
Score = 67.4 bits (163), Expect = 3e-11
Identities = 37/124 (29%), Positives = 71/124 (57%), Gaps = 12/124 (9%)
Query: 8 KQEEKHLKMLRDMTGLPHNRKCFDCDQRGPTYVNMTVGSFVCTSCSGSLRGLNPP-HRVK 66
K +++ +L ++ N+ C DC +GP + + +G F+C C+G R L RVK
Sbjct: 7 KDVDRYQAVLANLLLEEDNKFCADCQSKGPRWASWNIGVFICIRCAGIHRNLGVHISRVK 66
Query: 67 SISMTTFTQQEIEFLQKHGNEVCKQIWLGLFDDRSSAIPD-FRDPQ---KVKEFLQEKYE 122
S+++ +TQ++I+ +Q+ GN +++ + +P+ FR PQ V+ F+++KYE
Sbjct: 67 SVNLDQWTQEQIQCMQEMGNGKANRLY-------EAYLPETFRRPQIDPAVEGFIRDKYE 119
Query: 123 KKRW 126
KK++
Sbjct: 120 KKKY 123
Score = 30.0 bits (66), Expect = 6.1
Identities = 37/155 (23%), Positives = 54/155 (34%), Gaps = 18/155 (11%)
Query: 421 TSNASSNVFGTVPVVASAQTQPASSSVPAPFGATPSTNPFVAAAGPSVASSTNPFQTNAR 480
+S+ S V G++P SA + P + ++ G+ + S+ S QT
Sbjct: 221 SSSGSRKVVGSMPTAGSAGSVPENLNLFPEPGSKSEEIGKKQLSKDSILSLYGS-QTPQM 279
Query: 481 GATAATFGTASMSMPTGFGTPAPYSLPTSFSGSFQQPAFPAQAAFPQQTAFSQQPNGFAA 540
A A M+ PT + + + P S GS P A QP A
Sbjct: 280 PTQAMFMAPAQMAYPTAYPSFPGVTPPNSIMGSMMPPPVGMVA----------QP---GA 326
Query: 541 FGQTKPVVTPFGQVAAAGVSSNPFMTGAPTGQFPT 575
G P+ P G + S M G P G T
Sbjct: 327 SGMVAPMAMPAGYMGGMQAS----MMGVPNGMMTT 357
>gi|6806913 centaurin, alpha 1 [Homo sapiens]
Length = 374
Score = 65.9 bits (159), Expect = 1e-10
Identities = 34/116 (29%), Positives = 61/116 (52%), Gaps = 14/116 (12%)
Query: 24 PHNRKCFDCDQRGPTYVNMTVGSFVCTSCSGSLRGLNPPHRVKSISMTTFTQQEIEFLQK 83
P N +C DC P + + T+G F+C SCSG R + +VKS+ + + + ++EF+
Sbjct: 16 PGNARCADCGAPDPDWASYTLGVFICLSCSGIHRNIPQVSKVKSVRLDAWEEAQVEFMAS 75
Query: 84 HGNEVCKQIWLGLFDDRSSAIPDF------RDPQKVKE-FLQEKYEKKRWYVPPEQ 132
HGN+ + + S +P F D Q ++E +++ KYE++ + P +Q
Sbjct: 76 HGNDAARARF-------ESKVPSFYYRPTPSDCQLLREQWIRAKYERQEFIYPEKQ 124
>gi|161016767 mucin 21 [Homo sapiens]
Length = 566
Score = 65.5 bits (158), Expect = 1e-10
Identities = 87/371 (23%), Positives = 159/371 (42%), Gaps = 18/371 (4%)
Query: 142 SISGSSASSTSSTPEVKPLKSLLGDSAPTLHLNKGTPSQSPVVGRSQGQQQEKKQFDLLS 201
SI+ +S SST+S+ S S P+ + T S S S
Sbjct: 103 SIATNSESSTTSSGASTATNS--ESSTPSSGASTATNSDSSTTSSGASTATNSDS----S 156
Query: 202 DLGSDIFAAPAPQSTATANFANFAHFNSHAAQNSANADFANFDAFGQSSGSSNFGGFPTA 261
S+ A +S+ T++ A+ A NS ++ S+ A A S S+ G TA
Sbjct: 157 TTSSEASTATNSESSTTSSGASTAT-NSESSTVSSRASTAT-----NSESSTTSSGASTA 210
Query: 262 SHSPFQPQTTAFRMLSSSCSFGEFTSAFPLQATHSGSAASVNANFAHFDNFPKSSSADFG 321
++S + +TT+ +++ S TS+ AT+S S+ + ++ ++S+ G
Sbjct: 211 TNS--ESRTTSNGAGTATNSESSTTSSGASTATNSESSTPSSGAGTATNSESSTTSSGAG 268
Query: 322 TFNTSQSHQTASAVSKVSTNKAGLQTADKYAALANLDNIFSAGQGGDQGSGFGTT--GKA 379
T S+S +S +S V+ +++ ++ A + + S+G S TT G +
Sbjct: 269 TATNSESSTVSSGISTVTNSESSTPSSGANTATNSESSTTSSGANTATNSDSSTTSSGAS 328
Query: 380 PVGSVVSVPSQSSASSDKYAALAELDSVFSSAATSSNAYTSTSNASSNVFGTVPVVASAQ 439
+ S + S AS+ + + S S+A S ++ TS+ +++ + V + A
Sbjct: 329 TATNSESSTTSSGASTATNSESSTTSSGASTATNSGSSTTSSGTSTATNSESSTVSSGAS 388
Query: 440 TQPASSSVPAPFGATPSTNPFVAAAGPSVASSTN-PFQTNARGATAATFGTASMSMPTGF 498
T S S GA+ +TN + +++TN T + GA AT +S++ G
Sbjct: 389 TATTSESSTTSSGASTATNSESSTVSSGASTATNSESSTTSSGANTATNSGSSVT-SAGS 447
Query: 499 GTPAPYSLPTS 509
GT A + T+
Sbjct: 448 GTAALTGMHTT 458
Score = 57.8 bits (138), Expect = 3e-08
Identities = 78/316 (24%), Positives = 137/316 (43%), Gaps = 27/316 (8%)
Query: 201 SDLGSDIFAAPAPQSTATANFANFAHFNSHAAQNSANADFANFDAFGQSSGSSNFGGFPT 260
S + S I A +S+ T++ A+ A + + +S + N D+ SSG+S +
Sbjct: 96 STVSSGISIATNSESSTTSSGASTATNSESSTPSSGASTATNSDSSTTSSGASTATNSDS 155
Query: 261 ASHSPFQPQTTAFRMLSSSCSFGEFT---------SAFPLQATHSGSAASVNANFAHFDN 311
++ S +TA SS+ S G T S+ AT+S S+ + + ++
Sbjct: 156 STTS--SEASTATNSESSTTSSGASTATNSESSTVSSRASTATNSESSTTSSGASTATNS 213
Query: 312 FPKSSSADFGTFNTSQSHQTASAVSKVSTNKAGLQTADKYAALANLDNIFSAGQGGDQGS 371
+++S GT S+S T+S S + +++ ++ A + + S+G G S
Sbjct: 214 ESRTTSNGAGTATNSESSTTSSGASTATNSESSTPSSGAGTATNSESSTTSSGAGTATNS 273
Query: 372 GFGTTGKAPVGSVVSVPSQSSASSDKYAALAELDSVFSSAAT---SSNAYTST--SNASS 426
T + +V + S + +S A +E + S A T S ++ TS+ S A++
Sbjct: 274 ESSTVSSG-ISTVTNSESSTPSSGANTATNSESSTTSSGANTATNSDSSTTSSGASTATN 332
Query: 427 NVFGTVPVVASAQTQPASSSVPAPFGATPSTNPFVAAAGPSVASSTNPFQTNARGAT--- 483
+ T AS T SS+ + GA+ +TN +G S SS TN+ +T
Sbjct: 333 SESSTTSSGASTATNSESSTTSS--GASTATN-----SGSSTTSSGTSTATNSESSTVSS 385
Query: 484 AATFGTASMSMPTGFG 499
A+ T S S T G
Sbjct: 386 GASTATTSESSTTSSG 401
Score = 44.3 bits (103), Expect = 3e-04
Identities = 67/269 (24%), Positives = 115/269 (42%), Gaps = 30/269 (11%)
Query: 248 QSSGSSNFGGFPTASHSPFQPQTTAFRMLSSSCSFGEFTSAFPLQATHSGSAASVNANFA 307
++S S+N G +S + +TA SS S G T AT SGS+ + N
Sbjct: 26 ETSTSANTGSSVISSGA-----STATNSGSSVTSSGVST------ATISGSSVTSNGVSI 74
Query: 308 HFDNFPKSSSADFGTFNTSQSHQTASAVSKVSTNKAGLQTADKYAALANLDNIFSAGQGG 367
++ ++S+ T S+ +S +S + +++ ++ A + + S+G
Sbjct: 75 VTNSEFHTTSSGISTATNSEFSTVSSGISIATNSESSTTSSGASTATNSESSTPSSGAST 134
Query: 368 DQGSGFGTTGKAPVGSVVSVPSQSSASSDKYAALAELDSVFSSAATSSNAYTST--SNAS 425
S TT G+ + S SS +S S S+A S ++ TS+ S A+
Sbjct: 135 ATNSDSSTTSS---GASTATNSDSSTTS----------SEASTATNSESSTTSSGASTAT 181
Query: 426 SNVFGTVPVVASAQTQPASSSVPAPFGATPSTNPFVAAAGPSVASSTN-PFQTNARGATA 484
++ TV AS T SS+ + GA+ +TN ++TN T + GA+
Sbjct: 182 NSESSTVSSRASTATNSESSTTSS--GASTATNSESRTTSNGAGTATNSESSTTSSGAST 239
Query: 485 ATFGTASMSMPTGFGTPAPYSLPTSFSGS 513
AT + S + +G GT T+ SG+
Sbjct: 240 AT-NSESSTPSSGAGTATNSESSTTSSGA 267
Score = 30.4 bits (67), Expect = 4.7
Identities = 35/164 (21%), Positives = 68/164 (41%), Gaps = 8/164 (4%)
Query: 411 AATSSNAYTSTSNASSNVFGTVPVVASAQTQPASSSVPAPFGATPSTNPFVAAAGPSVAS 470
AAT+SN ++++N S+V + AS T SS + + V + G S+ +
Sbjct: 20 AATNSNETSTSANTGSSVISS---GASTATNSGSSVTSSGVSTATISGSSVTSNGVSIVT 76
Query: 471 STNPFQTNARGATAAT---FGTASMSMPTGFGTPAPYSLPTSFSGSFQQPAFPAQAAFPQ 527
++ F T + G + AT F T S + + + + + + + + + P+ A
Sbjct: 77 NSE-FHTTSSGISTATNSEFSTVSSGISIATNSESSTTSSGASTATNSESSTPSSGASTA 135
Query: 528 QTAFSQQPNGFAAFGQTKPVVTPFGQVAAAGVS-SNPFMTGAPT 570
+ S + A+ T + + A S S+ +GA T
Sbjct: 136 TNSDSSTTSSGASTATNSDSSTTSSEASTATNSESSTTSSGAST 179
>gi|8922652 ADP-ribosylation factor GTPase activating protein 1
isoform a [Homo sapiens]
Length = 406
Score = 63.9 bits (154), Expect = 4e-10
Identities = 61/242 (25%), Positives = 108/242 (44%), Gaps = 28/242 (11%)
Query: 15 KMLRDMTGLPHNRKCFDCDQRGPTYVNMTVGSFVCTSCSGSLRGLNPP-HRVKSISMTTF 73
K+L+++ N CF+C P +V++T G ++C CSG RGL V+S++M +
Sbjct: 8 KVLKEVRVQDENNVCFECGAFNPQWVSVTYGIWICLECSGRHRGLGVHLSFVRSVTMDKW 67
Query: 74 TQQEIEFLQKHGNEVCKQI----------WLGLFDDRSSAIPDFRDP----QKVKEFLQE 119
E+E ++ GN ++ W S A FRD + +E+ E
Sbjct: 68 KDIELEKMKAGGNAKFREFLESQEDYDPCWSLQEKYNSRAAALFRDKVVALAEGREWSLE 127
Query: 120 KYEKKRWYVPPEQAKVVASVHASISGSSASSTSSTPEVKPLKSLLGDSAPTLHLNKGTPS 179
+ W PP+ + + VH +SG S T+S+ K + L D + +G
Sbjct: 128 SSPAQNW-TPPQPRTLPSMVH-RVSGQPQSVTASSD--KAFEDWLNDDLGSYQGAQG--- 180
Query: 180 QSPVVGRSQGQQQEKKQFDLLSDLGSDIFAAPAPQSTATANFANFA-----HFNSHAAQN 234
+ VG +KK+ D L++ S +++ + +T + FA+ A F S A+Q
Sbjct: 181 -NRYVGFGNTPPPQKKEDDFLNNAMSSLYSGWSSFTTGASRFASAAKEGATKFGSQASQK 239
Query: 235 SA 236
++
Sbjct: 240 AS 241
>gi|28416436 ADP-ribosylation factor GTPase activating protein 1
isoform b [Homo sapiens]
Length = 414
Score = 63.2 bits (152), Expect = 7e-10
Identities = 61/239 (25%), Positives = 106/239 (44%), Gaps = 28/239 (11%)
Query: 15 KMLRDMTGLPHNRKCFDCDQRGPTYVNMTVGSFVCTSCSGSLRGLNPP-HRVKSISMTTF 73
K+L+++ N CF+C P +V++T G ++C CSG RGL V+S++M +
Sbjct: 8 KVLKEVRVQDENNVCFECGAFNPQWVSVTYGIWICLECSGRHRGLGVHLSFVRSVTMDKW 67
Query: 74 TQQEIEFLQKHGNEVCKQI----------WLGLFDDRSSAIPDFRDP----QKVKEFLQE 119
E+E ++ GN ++ W S A FRD + +E+ E
Sbjct: 68 KDIELEKMKAGGNAKFREFLESQEDYDPCWSLQEKYNSRAAALFRDKVVALAEGREWSLE 127
Query: 120 KYEKKRWYVPPEQAKVVASVHASISGSSASSTSSTPEVKPLKSLLGDSAPTLHLNKGTPS 179
+ W PP+ + + VH +SG S T+S+ K + L D + +G
Sbjct: 128 SSPAQNW-TPPQPRTLPSMVH-RVSGQPQSVTASSD--KAFEDWLNDDLGSYQGAQG--- 180
Query: 180 QSPVVGRSQGQQQEKKQFDLLSDLGSDIFAAPAPQSTATANFANFA-----HFNSHAAQ 233
+ VG +KK+ D L++ S +++ + +T + FA+ A F S A+Q
Sbjct: 181 -NRYVGFGNTPPPQKKEDDFLNNAMSSLYSGWSSFTTGASRFASAAKEGATKFGSQASQ 238
>gi|80978934 centaurin, gamma 2 isoform 2 [Homo sapiens]
Length = 804
Score = 59.3 bits (142), Expect = 9e-09
Identities = 33/123 (26%), Positives = 62/123 (50%), Gaps = 5/123 (4%)
Query: 8 KQEEKHLKMLRDMTGLPHNRKCFDCDQRGPTYVNMTVGSFVCTSCSGSLRGLNPP-HRVK 66
+ E L+ +R+M G H C DC+ + P + ++ +G+ +C CSG R L RV+
Sbjct: 553 QSEAMALQSIRNMRGNSH---CVDCETQNPNWASLNLGALMCIECSGIHRNLGTHLSRVR 609
Query: 67 SISMTTFTQQEIEFLQKHGNEVCKQIWLGLFDDRSSAIPDFRDPQKVKEFLQEKYEKKRW 126
S+ + + + I+ + GNE+ +W R+ D +K + +++ KYE+K +
Sbjct: 610 SLDLDDWPVELIKVMSSIGNELANSVWEESSQGRTKPSVDSTREEK-ERWIRAKYEQKLF 668
Query: 127 YVP 129
P
Sbjct: 669 LAP 671
>gi|80978930 centaurin, gamma 2 isoform 1 [Homo sapiens]
Length = 857
Score = 59.3 bits (142), Expect = 9e-09
Identities = 33/123 (26%), Positives = 62/123 (50%), Gaps = 5/123 (4%)
Query: 8 KQEEKHLKMLRDMTGLPHNRKCFDCDQRGPTYVNMTVGSFVCTSCSGSLRGLNPP-HRVK 66
+ E L+ +R+M G H C DC+ + P + ++ +G+ +C CSG R L RV+
Sbjct: 606 QSEAMALQSIRNMRGNSH---CVDCETQNPNWASLNLGALMCIECSGIHRNLGTHLSRVR 662
Query: 67 SISMTTFTQQEIEFLQKHGNEVCKQIWLGLFDDRSSAIPDFRDPQKVKEFLQEKYEKKRW 126
S+ + + + I+ + GNE+ +W R+ D +K + +++ KYE+K +
Sbjct: 663 SLDLDDWPVELIKVMSSIGNELANSVWEESSQGRTKPSVDSTREEK-ERWIRAKYEQKLF 721
Query: 127 YVP 129
P
Sbjct: 722 LAP 724
>gi|24430146 nucleoporin 153kDa [Homo sapiens]
Length = 1475
Score = 57.8 bits (138), Expect = 3e-08
Identities = 90/340 (26%), Positives = 126/340 (37%), Gaps = 60/340 (17%)
Query: 254 NFGGFPTASHSPFQPQTTAFRMLSSSCSFGEFTSAFPLQATHS-GSAASVNANFAHFDNF 312
+FG T +F M S E S P +AT + G+ S A+
Sbjct: 1134 SFGNSEQTKDENSSKSTFSFSMTKPS----EKESEQPAKATFAFGAQTSTTADQG----- 1184
Query: 313 PKSSSADFGTFNTSQSHQTASAVSKVSTNKAGLQTADKYAALANLDNIFSAGQGGDQGSG 372
++ F N S S + A S G T+ +A +F S
Sbjct: 1185 --AAKPVFSFLNNSSSSSSTPATS-AGGGIFGSSTSSSNPPVATF--VFGQSSNPVSSSA 1239
Query: 373 FGTTGKAPVGSVVSVPSQSSASSDKYAALAELDSVFSSAATSSNAYTS----------TS 422
FG T ++ + S ++ A VF A+S+N TS +S
Sbjct: 1240 FGNTAESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATTTSSS 1299
Query: 423 NASSNVFGTVPVVASAQTQPASSSVPAPFGATPSTNPFVAAAGPSVASSTNPFQTNARGA 482
SS VFGT P SA PA FGA T F + G AS NP + +
Sbjct: 1300 AGSSFVFGTGPSAPSAS--------PA-FGAN-QTPTFGQSQG---ASQPNPPGFGSISS 1346
Query: 483 TAATFGTASMSMPTGFGTPAPYSLPTSFSGSFQQPAFPAQAAFPQQTAFSQQPNGFAAFG 542
+ A F T S P FGT + S P F QQ P+Q+AF T PN +AF
Sbjct: 1347 STALFPTGSQPAPPTFGTVSSSSQPPVFG---QQ---PSQSAFGSGTT----PNSSSAF- 1395
Query: 543 QTKPVVTPFGQVAAAGVSSNPFMTGAPTGQFPTGSSSTNP 582
FG + ++ F +P+G F G++S+ P
Sbjct: 1396 -------QFG----SSTTNFNFTNNSPSGVFTFGANSSTP 1424
Score = 42.7 bits (99), Expect = 0.001
Identities = 69/329 (20%), Positives = 116/329 (35%), Gaps = 59/329 (17%)
Query: 224 FAHFNSHAAQNSANADFANFDAFGQSSGSSNFGGFPTASHSPFQPQTTAFRMLSSSCSFG 283
F+ N+ ++ +S A A FG S+ SSN P F FG
Sbjct: 1190 FSFLNNSSSSSSTPATSAGGGIFGSSTSSSN-------------PPVATF-------VFG 1229
Query: 284 EFTSAFPLQATHSGSAASVNANFAHFDNFPKSSSADFGTFNTSQSHQTASAVSKVSTNKA 343
+ ++ A + + +S + + + ++++ GT T ++ + +T+
Sbjct: 1230 QSSNPVSSSAFGNTAESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSNNTTTSGF 1289
Query: 344 GLQTADKYAALANLDNIFSAGQGGDQGSGFGTTGKAPVGSVVSVPSQSSASSDKYAALAE 403
G + FGT AP S +Q+ A
Sbjct: 1290 GFGAT-------------TTSSSAGSSFVFGTGPSAPSASPAFGANQTPTFGQSQGASQP 1336
Query: 404 LDSVFSSAATSSNAYTSTSNASSNVFGTVPVVASAQTQPASSSVPAPFGATPSTNPFVAA 463
F S ++S+ + + S + FGTV +SSS P FG PS + F +
Sbjct: 1337 NPPGFGSISSSTALFPTGSQPAPPTFGTV----------SSSSQPPVFGQQPSQSAFGSG 1386
Query: 464 AGPSVASSTNPFQTNARGATAATFGTASMSMPTGFGTPAPYSLPTSFSGSFQQPAFPAQA 523
P +S++ FQ G++ F + S P+G T F + PA AQ
Sbjct: 1387 TTP---NSSSAFQF---GSSTTNFNFTNNS-PSGVFT---------FGANSSTPAASAQP 1430
Query: 524 AFPQQTAFSQQPNGFAAFGQTKPVVTPFG 552
+ F+Q P F K V + G
Sbjct: 1431 SGSGGFPFNQSPAAFTVGSNGKNVFSSSG 1459
>gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens]
Length = 5765
Score = 57.0 bits (136), Expect = 5e-08
Identities = 116/501 (23%), Positives = 176/501 (35%), Gaps = 55/501 (10%)
Query: 129 PPEQAKVVASVHASISGSSASSTSSTPEVKPLKSLLGDSAPTLHLNKGTPSQSPVVG--- 185
P A V ++ + SS +T+ TP V + PT+ +K TPS SP
Sbjct: 4456 PSTTATVTVPTGSTATASSTQATAGTPHVSTTAT-----TPTVTSSKATPSSSPGTATAL 4510
Query: 186 ---RSQGQQQEKKQFDLL--SDLGSDIFAAPAPQSTATANFANFAHFNSHAAQNSANADF 240
RS F + S LG+ + + +T TA + ++ +++
Sbjct: 4511 PALRSTATTPTATSFTAIPSSSLGT-TWTRLSQTTTPTATMSTATPSSTPETVHTSTVLT 4569
Query: 241 ANFDAFGQSSGSSNFGGFPTASHSPFQPQTTAFRMLSSSCSFGEFTSAFPLQATHSGSAA 300
A G + + P +H+ P TT ++ S P+ + + +
Sbjct: 4570 ATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPT 4629
Query: 301 SVNANFAHFDNFPKSSSADFGTFNTSQSHQTASAVSKVSTNKAGLQTADKYAAL-ANLDN 359
+ + P S T + T A ++T + QT+ +L
Sbjct: 4630 TTTPTTSGSTVTPSSIPGTTHTARVLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATT 4689
Query: 360 IFSAGQGGDQGSGFGTTGKAPV-GSVVSVP--SQSSASSDKYAALAELDSVFSSAATSSN 416
I + G + S GTT PV S + P + S A+S A V +S AT S
Sbjct: 4690 ITATGSTTNPSSTPGTTPITPVLTSTATTPAATSSKATSSSSPRTATTLPVLTSTATKST 4749
Query: 417 AYTSTSNASSNVFGTVPVVASAQTQPASSSVPAPFGATPST--NPFVAAAGPSVASSTNP 474
A + T SS ++ T V A T P S+ +TP T V ++ +TN
Sbjct: 4750 ATSFTPIPSSTLWTTWTVPAQT-TTPMSTMSTIHTSSTPETTHTSTVLTTTATMTRATNS 4808
Query: 475 FQ---------------TNARGATAATFGTASMSMPTGF-------GTPAPYSLPT---- 508
T TAAT TA++S G T A +PT
Sbjct: 4809 TATPSSTLGTTRILTELTTTATTTAATGSTATLSSTPGTTWILTEPSTIATVMVPTGSTA 4868
Query: 509 ---SFSGSFQQP-AFPAQAAFPQQTAFSQQPNGFAAFGQTKPVVTP--FGQVAAAGVSSN 562
S G+ P A P TA S P+ P V P + + VSS+
Sbjct: 4869 TASSTLGTAHTPKVVTTMATMPTATA-STVPSSSTVGTTRTPAVLPSSLPTFSVSTVSSS 4927
Query: 563 PFMTGAPTGQFPTGSSSTNPF 583
T PTG FP+ ST F
Sbjct: 4928 VLTTLRPTG-FPSSHFSTPCF 4947
Score = 49.7 bits (117), Expect = 7e-06
Identities = 89/443 (20%), Positives = 151/443 (34%), Gaps = 65/443 (14%)
Query: 143 ISGSSASSTSSTPEVKPLKSLLGDSAPTLHLNKGTPSQSPVVGRSQGQQQEKKQFDLLSD 202
++ S SSTPE ++L A T T + S G + +L++
Sbjct: 4348 VATMSTIHPSSTPETTHTSTVLTTKATTTRATSSTSTPSSTPGTTW----------ILTE 4397
Query: 203 LGSDIFAAPAPQSTATANFANFAHFNSHAAQNSANADFANFDAFGQSSGSSNFGGFPTAS 262
L + A TAT + ++ + + ++ +++ G T S
Sbjct: 4398 LTTAATTTAATGPTATPS-------------STPGTTWILTELTTTATTTASTGSTATPS 4444
Query: 263 HSP------FQPQTTAFRMLSSSCSFGEFTSAFPLQATHSGSAASVNANFAHFDNFPKSS 316
+P +P TTA T P +T + S+ A H +
Sbjct: 4445 STPGTTWILTEPSTTA-------------TVTVPTGSTATASSTQATAGTPHVSTTATTP 4491
Query: 317 SADFGTFNTSQSHQTASAVSKVSTNKAGLQTADKYAALANLDNIFSAGQGGDQGSGFGTT 376
+ S S TA+A+ + + A TA + A+ + S GTT
Sbjct: 4492 TVTSSKATPSSSPGTATALPALRST-ATTPTATSFTAIPS--------------SSLGTT 4536
Query: 377 GKAPVGSVVSVPSQSSASSDKYAALAELDSVFSSAATSSNAYTSTSNASSNVFGTVPVVA 436
+ + S+A+ +V ++ AT++ A S + SS
Sbjct: 4537 WTRLSQTTTPTATMSTATPSSTPETVHTSTVLTATATTTGATGSVATPSS-------TPG 4589
Query: 437 SAQTQPASSSVPAPFGATPSTNPFVAAAGPSVASSTNPFQTNARGATAATFGTASMSMPT 496
+A T ++ F ATPS++P A P S+T T + +T +S+ T
Sbjct: 4590 TAHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTTTPTTSGSTVTPSSIPGTT 4649
Query: 497 GFGTPAPYSLPTSFSGSFQQPAFPAQAAFPQQTAFSQQPNGFAAFGQTKPVVTPFGQVAA 556
+ T +GS P+ Q + + + A T P TP G
Sbjct: 4650 HTARVLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATTITATGSTTNPSSTP-GTTPI 4708
Query: 557 AGVSSNPFMTGAPTGQFPTGSSS 579
V ++ T A T T SSS
Sbjct: 4709 TPVLTSTATTPAATSSKATSSSS 4731
Score = 48.9 bits (115), Expect = 1e-05
Identities = 85/366 (23%), Positives = 133/366 (36%), Gaps = 60/366 (16%)
Query: 263 HSPFQPQTTAFRMLSSSCSFGEFTSAFPLQATHSGSAASVNANFAHFDNFP--KSSSADF 320
H P P T++ M SS+ + AT + S S + P K ++
Sbjct: 4230 HCPSTPATSSTAMPSSTPGTTWILTELTTTATTTASTGSTATPSSTPGTAPPPKVLTSPA 4289
Query: 321 GTFNTSQSHQTASAVSKVSTNKAGLQTADKYAALANLDNIFSAGQGGDQGSGFGTTGKAP 380
T + S T+S+ + +T L + + ++ I S S GTTG P
Sbjct: 4290 TTPTATSSKATSSSSPRTATTLPVLTSTATKSTATSVTPIPS--------STLGTTGTLP 4341
Query: 381 VGSVVSVPSQSSASSDKYAALAELDSVFSSAATSSNAYTSTSNASSNVFGTVPVVASAQT 440
+ V + S+ +V ++ AT++ A +STS SS GT ++ T
Sbjct: 4342 EQTTTPVATMSTIHPSSTPETTHTSTVLTTKATTTRATSSTSTPSSTP-GTTWILTELTT 4400
Query: 441 QPASSSVPAPFGATPSTNP--------------FVAAAGPSVASSTNPF----------- 475
+++ P ATPS+ P A+ G + S+ P
Sbjct: 4401 AATTTAATGPT-ATPSSTPGTTWILTELTTTATTTASTGSTATPSSTPGTTWILTEPSTT 4459
Query: 476 --------QTNARGATAATFGTASMSMPTGFGTPAPYS---LPTSFSGSFQQ-PAFPAQA 523
T +T AT GT +S T TP S P+S G+ PA + A
Sbjct: 4460 ATVTVPTGSTATASSTQATAGTPHVS--TTATTPTVTSSKATPSSSPGTATALPALRSTA 4517
Query: 524 AFPQQTAFSQQPNGFAAFGQTK--PVVTPFGQVAAAGVSSNP-------FMTGAPTGQFP 574
P T+F+ P+ T+ TP ++ A SS P +T T
Sbjct: 4518 TTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTATATTTGA 4577
Query: 575 TGSSST 580
TGS +T
Sbjct: 4578 TGSVAT 4583
Score = 40.8 bits (94), Expect = 0.003
Identities = 87/395 (22%), Positives = 148/395 (37%), Gaps = 40/395 (10%)
Query: 144 SGSSASSTSSTPEVKPLKSLLGDSA-PTLHLNKGTPSQSPVVG------RSQGQQQEKKQ 196
+GS+A+ TS+ P K L + PT+ +K TPS SP RS
Sbjct: 1923 TGSTATPTSTLRTAPPPKVLTTTATTPTVTSSKATPSSSPGTATALPALRSTATTPTATS 1982
Query: 197 FDLL--SDLGSDIFAAPAPQSTATANFANFAHFNSHAAQNSANADFANFDAFGQSSGSSN 254
+ S LG+ + + +T TA + ++ +++ A G + +
Sbjct: 1983 VTPIPSSSLGT-TWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTATATTTGATGSVAT 2041
Query: 255 FGGFPTASHSPFQP--QTTAFRMLSSSCSFGEFTSAFPLQATHSGSAASVNANFAHFDNF 312
P +H+ P TT F SS T + T + +
Sbjct: 2042 PSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVT------- 2094
Query: 313 PKSSSADFGTFNTSQSHQTASAVSKVSTNKAGLQTADKYAAL-ANLDNIFSAGQGGDQGS 371
P S T + T A ++T + QT+ +L I + G + S
Sbjct: 2095 PSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATTITATGSTTNPSS 2154
Query: 372 GFGTTGKAPV-GSVVSVPSQSSASSDKYAALAELDS--VFSSAATS----------SNAY 418
GTT PV + + P+ +S + +AL + V ++ AT+
Sbjct: 2155 TPGTTPIPPVLTTTATTPAATSNTVTPSSALGTTHTPPVPNTMATTHGRSLPPSSPHTVR 2214
Query: 419 TSTSNASSNVFGTVPVVASAQTQPASSSVPAPFGATPSTNPFVAAAGPSVASSTNPFQ-- 476
T+ ++A+S + GT + + S ++ A G T + P +++ PS ++ +P
Sbjct: 2215 TAWTSATSGILGTTHITEPSTV--TSHTLAATTGTTQHSTPALSSPHPSSRTTESPPSPG 2272
Query: 477 TNARGATAATFGTASMSMP--TGFGTPAPYSLPTS 509
T G T AT T + + P T T P S PTS
Sbjct: 2273 TTTPGHTTATSRTTATATPSKTRTSTLLP-SSPTS 2306
Score = 40.8 bits (94), Expect = 0.003
Identities = 78/352 (22%), Positives = 126/352 (35%), Gaps = 38/352 (10%)
Query: 260 TASHSPFQPQTTAFRMLSSSCSFGEFTSAFPLQATHSGSAASV----NANFAHFDNFPKS 315
T+S SP T +L+S+ + TS P+ + G+ ++ A S
Sbjct: 3043 TSSSSP--RTATTLPVLTSTATKSTATSFTPIPSFTLGTTGTLPEQTTTPMATMSTIHPS 3100
Query: 316 SSADFGTFNT--SQSHQTASAVSKVSTNKAGLQTADKYAALANLDNIFSA-GQGGDQGSG 372
S+ + +T + T A S +ST + T L +A G S
Sbjct: 3101 STPETTHTSTVLTTKATTTRATSSMSTPSSTPGTTWILTELTTAATTTAATGPTATPSST 3160
Query: 373 FGTTG---KAPVGSVVSVPSQSSASSDKYAALAELDSVFSSAAT-----------SSNAY 418
GTT + + V+VP+ S+A++ A A V +S AT SS+
Sbjct: 3161 PGTTWILTEPSTTATVTVPTGSTATASSTRATAGTLKVLTSTATTPTVISSRATPSSSPG 3220
Query: 419 TSTSNASSNVFGTVPVVASAQTQPASSSVPAPFGATPSTNP--FVAAAGPSVASSTNPFQ 476
T+T+ + T P S P+SS A + +T P ++ A PS T
Sbjct: 3221 TATALPALRSTATTPTATSVTAIPSSSLGTAWTRLSQTTTPTATMSTATPSSTPETVHTS 3280
Query: 477 TNARGATAATFGTASMSMP-----TGFGTPAPYSLPTSFSG--------SFQQPAFPAQA 523
T T T T S++ P T T P + T F+ + P + +
Sbjct: 3281 TVLTTTTTTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTT 3340
Query: 524 AFPQQTAFSQQPNGFAAFGQTKPVVTPFGQVAAAGVSSNPFMTGAPTGQFPT 575
P + P+ T V+T A G + P + +G P+
Sbjct: 3341 TTPTTRGSTVTPSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQTSGTPPS 3392
Score = 39.7 bits (91), Expect = 0.008
Identities = 54/209 (25%), Positives = 94/209 (44%), Gaps = 22/209 (10%)
Query: 373 FGTTGKAPVGSVVSVPSQSSASSDKYAALAELDSVFSSAATSSNAYTSTSNASSNVFGTV 432
+G P S ++PS + ++ L EL ++ AT++ + ST+ SS GT
Sbjct: 2414 YGHCPSTPATSSTAMPSSTPGTT---WILTEL----TTTATTTESTGSTATPSSTP-GTT 2465
Query: 433 PVVASAQTQPASSSVPAPFGATPSTNPFVAAAG-PSVASS-TNPFQTNARGATAATFGTA 490
++ T +++V P G+T + + A AG P V+++ T P T+++ ++ GTA
Sbjct: 2466 WILTEPST---TATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPFSSPGTA 2522
Query: 491 SMSMPTGFGTPAPYSLPTSFSGSFQQPAFPAQAAFPQQTAFSQQPNGFAAFGQTKPVVTP 550
+ ++P + A TSF+ A P+ + T SQ A P TP
Sbjct: 2523 T-ALP-ALRSTATTPTATSFT------AIPSSSLGTTWTRLSQTTTPTATMSTATPSSTP 2574
Query: 551 FGQVAAAGVSSNPFMTGAPTGQFPTGSSS 579
+ +++ TGA TG T SS+
Sbjct: 2575 ETVHTSTVLTTTATTTGA-TGSVATPSST 2602
Score = 38.9 bits (89), Expect = 0.013
Identities = 55/223 (24%), Positives = 81/223 (36%), Gaps = 32/223 (14%)
Query: 376 TGKAPVGSVVSVPS-QSSASSDKYAALAELDSVFSSAATS-SNAYTSTSNASSNVFGTVP 433
T P GS + S Q++A + + A +V SS AT S+ T+T+ + T P
Sbjct: 2476 TVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPFSSPGTATALPALRSTATTP 2535
Query: 434 VVASAQTQPASSSVPAPFGATPSTNPFVAAAGPSVASSTNPFQTNARGATAATFGTASMS 493
S P+SS + +T P + + +S+ T+ T AT A+ S
Sbjct: 2536 TATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTTTATTTGATGS 2595
Query: 494 MPTGFGTPAPYSLPTSFSGSFQQPAFPAQAAFPQQTAFSQQPNGFAAFGQTKPV-----V 548
+ T TP A + T F+ P+ +T PV
Sbjct: 2596 VATPSSTPG--------------TAHTTKVLTTTTTGFTATPSSSPGTARTLPVWISTTT 2641
Query: 549 TPFGQVAAAGVSSNPFMTGAP-----------TGQFPTGSSST 580
TP + + SS P T P TG T SSST
Sbjct: 2642 TPTTRGSTVTPSSIPGTTHTPTVLTTTTTTVATGSMATPSSST 2684
Score = 38.9 bits (89), Expect = 0.013
Identities = 46/186 (24%), Positives = 76/186 (40%), Gaps = 20/186 (10%)
Query: 409 SSAATSSNAYTSTSNASSNVFGTVPVVASAQTQPASSSVPAPFGATPSTNPFVAAAGPSV 468
S+ ATSS A S++ ++ + + A+ S++ P+ +TP T + +
Sbjct: 3676 STPATSSTATPSSTPGTTWILTKLTTTATTTESTGSTATPS---STPGTTWILTEPSTTA 3732
Query: 469 ASSTNPFQTNARGATAATFGTASMS----MPTGFGTPA-PYSLPTSFSGSFQQPAFPAQA 523
+ T +T AT GT +S PT + A P+S P + + PA + A
Sbjct: 3733 TVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPFSSPGTATA---LPALRSTA 3789
Query: 524 AFPQQTAFSQQPNGFAAFGQTK--PVVTPFGQVAAAGVSSNP-------FMTGAPTGQFP 574
P T+F+ P+ T+ TP ++ A SS P +T T
Sbjct: 3790 TTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTTTATTTRA 3849
Query: 575 TGSSST 580
TGS +T
Sbjct: 3850 TGSVAT 3855
Score = 38.9 bits (89), Expect = 0.013
Identities = 56/223 (25%), Positives = 82/223 (36%), Gaps = 32/223 (14%)
Query: 376 TGKAPVGSVVSVPS-QSSASSDKYAALAELDSVFSSAATS-SNAYTSTSNASSNVFGTVP 433
T P GS + S Q++A + + A +V SS AT S+ T+T+ + T P
Sbjct: 3733 TVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPFSSPGTATALPALRSTATTP 3792
Query: 434 VVASAQTQPASSSVPAPFGATPSTNPFVAAAGPSVASSTNPFQTNARGATAATFGTASMS 493
S P+SS + +T P + + +S+ T+ T AT A+ S
Sbjct: 3793 TATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTTTATTTRATGS 3852
Query: 494 MPTGFGTPAPYSLPTSFSGSFQQPAFPAQAAFPQQTAFSQQPNGFAAFGQTKPV-----V 548
+ T P+S G+ P T F+ P+ +T PV
Sbjct: 3853 VAT----------PSSTPGTAHTTKVPTTTT----TGFTVTPSSSPGTARTPPVWISTTT 3898
Query: 549 TPFGQVAAAGVSSNPFMTGAP-----------TGQFPTGSSST 580
TP + SS P T P TG T SSST
Sbjct: 3899 TPTTSGSTVTPSSVPGTTHTPTVLTTTTTTVATGSMATPSSST 3941
Score = 38.1 bits (87), Expect = 0.023
Identities = 44/184 (23%), Positives = 65/184 (35%), Gaps = 28/184 (15%)
Query: 375 TTGKAPVGSVVSVPSQSSASSDKYAALAELDSVFSSAATSSNAYTSTSNASSNVFGTVPV 434
TT G+ SV + SS + T++ +T+T ++S T+PV
Sbjct: 2584 TTTATTTGATGSVATPSSTPGTAHTTKV--------LTTTTTGFTATPSSSPGTARTLPV 2635
Query: 435 VASAQTQPAS-------SSVPA----PFGATPSTNPFVAAAGPSVASSTNPFQTNARGAT 483
S T P + SS+P P T +T + + +SST T T
Sbjct: 2636 WISTTTTPTTRGSTVTPSSIPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTPPSLTT 2695
Query: 484 AATFGTASMSMPTGFGTPAPYSLPTSFSGSFQQPAFPAQAAFPQQTAFSQQPNGFAAFGQ 543
AT TA+ S TP +P P A P T+ + P+
Sbjct: 2696 TATTITATGSTTNPSSTPGTTPIP---------PVLTTTATTPAATSSTVTPSSALGTTH 2746
Query: 544 TKPV 547
T PV
Sbjct: 2747 TPPV 2750
Score = 37.7 bits (86), Expect = 0.029
Identities = 92/442 (20%), Positives = 157/442 (35%), Gaps = 44/442 (9%)
Query: 146 SSASSTSSTPEVKPLKSLLGDSAPTLHLNKGTPSQSPVVGRSQGQQQEKKQFDLLSDLGS 205
SS S+ SSTP + + L +A T T + S G + +L++ +
Sbjct: 3123 SSMSTPSSTPGTTWILTELTTAATTTAATGPTATPSSTPGTTW----------ILTEPST 3172
Query: 206 DIFAAPAPQSTATANFANFAHFNSHAAQNSANADFANFDAFGQSSGSSNFGGFPTASHSP 265
STATA+ ++A SS P +
Sbjct: 3173 TATVTVPTGSTATASSTRATAGTLKVLTSTATTPTVISSRATPSSSPGTATALPALRSTA 3232
Query: 266 FQPQTTAFRMLSSSCSFGEFTSAFPLQATHSGSAASVNANFAHFDNFPKSSSADFGTFNT 325
P T+ + SS S G T+ L T + +A A P S+ T +T
Sbjct: 3233 TTPTATSVTAIPSS-SLG--TAWTRLSQTTTPTATMSTAT-------PSSTPE---TVHT 3279
Query: 326 SQSHQTASAVSKVSTNKAGLQTADKYAALANLDNIFSAGQGGDQGSGFGTTGKAPVG-SV 384
S T + ++ + + A + A + + G S GT PV S
Sbjct: 3280 STVLTTTTTTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWIST 3339
Query: 385 VSVPSQ--SSASSDKYAALAELDSVFSSAATS-SNAYTSTSNASSNVFGTVP-VVASAQT 440
+ P+ S+ + +V ++ T+ + +T ++S+ GT P + +A T
Sbjct: 3340 TTTPTTRGSTVTPSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATT 3399
Query: 441 QPASSSVPAPFGATPSTNPFVAAAGPSVASSTNPFQTNARGATAATFGTASMSMPTGFGT 500
A+ S P +TP T P P V ++T AT++T T S ++ T
Sbjct: 3400 ITATGSTTNP-SSTPGTTPI-----PPVLTTT----ATTPAATSSTV-TPSSALGTTHTP 3448
Query: 501 PAPYSLPTSFSGSFQQPAFPAQAAFPQQTAFSQQPNGFAAFGQTKPVVTPFGQVAAAGVS 560
P P + T+ S P + +TA++ +G T AA S
Sbjct: 3449 PVPNTTATTHGRS-----LPPSSPHTVRTAWTSATSGILGTTHITEPSTVTSHTPAATTS 3503
Query: 561 SNPFMTGAPTGQFPTGSSSTNP 582
+ T A + P+ ++ +P
Sbjct: 3504 TTQHSTPALSSPHPSSRTTESP 3525
Score = 37.7 bits (86), Expect = 0.029
Identities = 93/418 (22%), Positives = 141/418 (33%), Gaps = 62/418 (14%)
Query: 129 PPEQAKVVASVHASISGSSASSTSSTPEVKPLKSLLGDSAPTLHLNKGTPSQSPVVG--- 185
P A V ++ + SS +T+ TP V + PT+ +K TP SP
Sbjct: 3728 PSTTATVTVPTGSTATASSTQATAGTPHVSTTAT-----TPTVTSSKATPFSSPGTATAL 3782
Query: 186 ---RSQGQQQEKKQFDLL--SDLG------SDIFAAPAPQSTATANFANFAHFNSHAAQN 234
RS F + S LG S A STAT + S
Sbjct: 3783 PALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTT 3842
Query: 235 SANADFANFDAFGQSS--GSSNFGGFPTASHSPFQPQTTAFRMLSSSCSFGEFTSAFPLQ 292
+A A SS G+++ PT + TT F + SS T +
Sbjct: 3843 TATTTRATGSVATPSSTPGTAHTTKVPTTT-------TTGFTVTPSSSPGTARTPPVWIS 3895
Query: 293 ATHSGSAASVNANFAHFDNFPKSSSADFGTFNTSQSHQTASAVSKVSTNKAGLQTADKYA 352
T + + + P S T + T A ++T + QT+
Sbjct: 3896 TTTTPTTSGSTVT-------PSSVPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTPP 3948
Query: 353 AL-ANLDNIFSAGQGGDQGSGFGTTGKAPV-GSVVSVPSQSSASSDKYAALAELDS--VF 408
+L I + G + S GTT PV + + P+ +S++ +AL + V
Sbjct: 3949 SLITTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSSTVTPSSALGTTHTPPVP 4008
Query: 409 SSAATSSNAYTSTSN----------ASSNVFGTVPVVA---------SAQTQPASSSVPA 449
++ AT+ S S+ A+S GT + +A T S PA
Sbjct: 4009 NTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSHTPAATTGTTQHSTPA 4068
Query: 450 PFGATPSTNPFVAAAGPSVASSTNPFQTNARGATAATFGTASMSMPTGFGTPAPYSLP 507
PS+ P +T P T A T AT T S + + +P S P
Sbjct: 4069 LSSPHPSSR---TTESPPSPGTTTPGHTTATSRTTAT-ATPSKTRTSTLLPSSPTSAP 4122
Score = 37.0 bits (84), Expect = 0.050
Identities = 48/216 (22%), Positives = 75/216 (34%), Gaps = 19/216 (8%)
Query: 382 GSVVSVPSQSSASSDKYAALAELDSVFSSAATSSNAYTSTSNASSNVFGTVP---VVASA 438
G S P+ SS ++ + A ++ A T ++ S+ GT P V+ S
Sbjct: 2972 GHCPSTPATSSTATPSSTPGTTWILTEQTTAATTTATTGSTAIPSSTPGTAPPPKVLTST 3031
Query: 439 QTQPASSSVPAPFGATPSTNP----FVAAAGPSVASSTNPFQTNARGATA-----ATFGT 489
T P ++S A ++P T + A S A+S P + G T T
Sbjct: 3032 ATTPTATSSKATSSSSPRTATTLPVLTSTATKSTATSFTPIPSFTLGTTGTLPEQTTTPM 3091
Query: 490 ASMSMPTGFGTPAPYSLPTSFSGSFQQPAFPAQAAFPQQT-----AFSQQPNGFAAFGQT 544
A+MS TP T + + + P T ++ T
Sbjct: 3092 ATMSTIHPSSTPETTHTSTVLTTKATTTRATSSMSTPSSTPGTTWILTELTTAATTTAAT 3151
Query: 545 KPVVTPFGQVAAAGVSSNPFMTGAPTGQFPTGSSST 580
P TP + + P T T PTGS++T
Sbjct: 3152 GPTATPSSTPGTTWILTEPSTTATVT--VPTGSTAT 3185
Score = 36.6 bits (83), Expect = 0.066
Identities = 76/343 (22%), Positives = 125/343 (36%), Gaps = 42/343 (12%)
Query: 259 PTASHSPFQPQT-----TAFRMLSSSCSFGEFTSAFPLQATHSGSA----ASVNANFAHF 309
PT + S P + TA L S+ + TS P+ ++ G+ + A
Sbjct: 1949 PTVTSSKATPSSSPGTATALPALRSTATTPTATSVTPIPSSSLGTTWTRLSQTTTPTATM 2008
Query: 310 DNFPKSSSADFGTFNT--SQSHQTASAVSKVSTNKAGLQTADKYAALANLDNIFSAGQGG 367
SS+ + +T + + T A V+T + TA F+A
Sbjct: 2009 STATPSSTPETAHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSS 2068
Query: 368 DQGSGFG-------TTGKAPVGSVVSVPSQSSASSDKYAALAELDSVFSSAATSSNAYTS 420
G+ TT GS V+ SS + A L + ++ AT S A
Sbjct: 2069 SPGTALTPPVWISTTTTPTTRGSTVT---PSSIPGTTHTATV-LTTTTTTVATGSMA--- 2121
Query: 421 TSNASSNVFGTVP-VVASAQTQPASSSVPAPFGATPSTNPFVAAAGPSVASSTNPFQTNA 479
T ++S+ GT P + +A T A+ S P +TP T P P V ++T
Sbjct: 2122 TPSSSTQTSGTPPSLTTTATTITATGSTTNP-SSTPGTTPI-----PPVLTTT----ATT 2171
Query: 480 RGATAATFGTASMSMPTGFGTPAPYSLPTSFSGSFQQPAFPAQAAFPQQTAFSQQPNGFA 539
AT+ T T S ++ T P P ++ T+ S P + +TA++ +G
Sbjct: 2172 PAATSNTV-TPSSALGTTHTPPVPNTMATTHGRS-----LPPSSPHTVRTAWTSATSGIL 2225
Query: 540 AFGQTKPVVTPFGQVAAAGVSSNPFMTGAPTGQFPTGSSSTNP 582
T AA + T A + P+ ++ +P
Sbjct: 2226 GTTHITEPSTVTSHTLAATTGTTQHSTPALSSPHPSSRTTESP 2268
Score = 36.2 bits (82), Expect = 0.086
Identities = 61/271 (22%), Positives = 91/271 (33%), Gaps = 47/271 (17%)
Query: 315 SSSADFGTFNTSQSHQTASAVSKVSTNKAGLQTADKYAALANLDNIFSAGQ-GGDQGSGF 373
S+ A GT + S + T + S +T + TA AL + +A S
Sbjct: 3746 STQATAGTPHVSTTATTPTVTSSKATPFSSPGTATALPALRSTATTPTATSFTAIPSSSL 3805
Query: 374 GTTGKAPVGSVVSVPSQSSASSDKYAALAELDSVFSSAATSSNA---------------- 417
GTT + + S+A+ A +V ++ AT++ A
Sbjct: 3806 GTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTTTATTTRATGSVATPSSTPGTAHT 3865
Query: 418 ----------YTSTSNASSNVFGTVPVVASAQTQPASS-------SVPA----PFGATPS 456
+T T ++S T PV S T P +S SVP P T +
Sbjct: 3866 TKVPTTTTTGFTVTPSSSPGTARTPPVWISTTTTPTTSGSTVTPSSVPGTTHTPTVLTTT 3925
Query: 457 TNPFVAAAGPSVASSTNPFQTNARGATAATFGTASMSMPTGFGTPAPYSLPTSFSGSFQQ 516
T + + +SST T T AT TA+ S TP +P
Sbjct: 3926 TTTVATGSMATPSSSTQTSGTPPSLITTATTITATGSTTNPSSTPGTTPIP--------- 3976
Query: 517 PAFPAQAAFPQQTAFSQQPNGFAAFGQTKPV 547
P A P T+ + P+ T PV
Sbjct: 3977 PVLTTTATTPAATSSTVTPSSALGTTHTPPV 4007
Score = 35.8 bits (81), Expect = 0.11
Identities = 44/163 (26%), Positives = 66/163 (40%), Gaps = 15/163 (9%)
Query: 376 TGKAPVGSVVSVPSQSSASSDKYAALAELDSVFSSAATSSNAYTSTSNASSNVFGTVPVV 435
T A GS ++PS + ++ L + + ATSS A TS++S T+PV+
Sbjct: 3004 TTTATTGST-AIPSSTPGTAPPPKVLTS--TATTPTATSSKA---TSSSSPRTATTLPVL 3057
Query: 436 ASAQTQ-PASSSVPAP---FGAT-----PSTNPFVAAAGPSVASSTNPFQTNARGATAAT 486
S T+ A+S P P G T +T P + +S+ T+ T AT
Sbjct: 3058 TSTATKSTATSFTPIPSFTLGTTGTLPEQTTTPMATMSTIHPSSTPETTHTSTVLTTKAT 3117
Query: 487 FGTASMSMPTGFGTPAPYSLPTSFSGSFQQPAFPAQAAFPQQT 529
A+ SM T TP + T + + A A P T
Sbjct: 3118 TTRATSSMSTPSSTPGTTWILTELTTAATTTAATGPTATPSST 3160
Score = 35.4 bits (80), Expect = 0.15
Identities = 53/216 (24%), Positives = 78/216 (36%), Gaps = 48/216 (22%)
Query: 409 SSAATSSNAYTSTSNASSNVFGTVPVVASAQTQPASSSVPAPFGATPSTNPFVAAAGPSV 468
++ T+S T+T ++ V+ + T P +S ATPS++P A A P++
Sbjct: 1916 TATTTASTGSTATPTSTLRTAPPPKVLTTTATTPTVTSSK----ATPSSSPGTATALPAL 1971
Query: 469 --------ASSTNPFQTNARGAT-----AATFGTASMSMPTGFGTP---------APYSL 506
A+S P +++ G T T TA+MS T TP +
Sbjct: 1972 RSTATTPTATSVTPIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTATAT 2031
Query: 507 PTSFSGSFQQP------AFPAQAAFPQQTAFSQQPNGFAAFGQTKPV-----VTPFGQVA 555
T +GS P A + T F+ P+ T PV TP + +
Sbjct: 2032 TTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTRGS 2091
Query: 556 AAGVSSNP-----------FMTGAPTGQFPTGSSST 580
SS P T TG T SSST
Sbjct: 2092 TVTPSSIPGTTHTATVLTTTTTTVATGSMATPSSST 2127
Score = 35.4 bits (80), Expect = 0.15
Identities = 82/410 (20%), Positives = 141/410 (34%), Gaps = 46/410 (11%)
Query: 129 PPEQAKVVASVHASISGSSASSTSSTPEVKPLKSLLGDSAPTLHLNKGTPSQSPVVG--- 185
P A V ++ + SS +T+ TP V + PT+ +K TP SP
Sbjct: 2471 PSTTATVTVPTGSTATASSTQATAGTPHVSTTAT-----TPTVTSSKATPFSSPGTATAL 2525
Query: 186 ---RSQGQQQEKKQFDLL--SDLGSDIFAAPAPQSTATANFANFAHFNSHAAQNSANADF 240
RS F + S LG+ + + +T TA + ++ +++
Sbjct: 2526 PALRSTATTPTATSFTAIPSSSLGTT-WTRLSQTTTPTATMSTATPSSTPETVHTSTVLT 2584
Query: 241 ANFDAFGQSSGSSNFGGFPTASHSPFQPQTTAFRMLSSSCSFGEFTSAFPLQATHSGSAA 300
G + + P +H+ TT ++ S P+ + + +
Sbjct: 2585 TTATTTGATGSVATPSSTPGTAHTTKVLTTTTTGFTATPSSSPGTARTLPVWISTTTTPT 2644
Query: 301 SVNANFAHFDNFPKSSSADFGTFNTSQSHQTASAVSKVSTNKAGLQTADKYAALANLDNI 360
+ + P S T + T A ++T + QT+ +L
Sbjct: 2645 TRGSTVT-----PSSIPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATT 2699
Query: 361 FSA-GQGGDQGSGFGTTGKAPV-GSVVSVPSQSSASSDKYAALAELDS--VFSSAATSSN 416
+A G + S GTT PV + + P+ +S++ +AL + V ++ AT+
Sbjct: 2700 ITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSSTVTPSSALGTTHTPPVPNTTATTHG 2759
Query: 417 AYTSTSN----------ASSNVFGTVPVVA---------SAQTQPASSSVPAPFGATPST 457
S S+ A+S GT + +A T S PA PS+
Sbjct: 2760 RSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSHTPAATTGTTQHSTPALSSPHPSS 2819
Query: 458 NPFVAAAGPSVASSTNPFQTNARGATAATFGTASMSMPTGFGTPAPYSLP 507
P +T P T A T AT T S + + +P S P
Sbjct: 2820 R---TTESPPSPGTTTPGHTRATSRTTAT-ATPSKTRTSTLLPSSPTSAP 2865
Score = 33.1 bits (74), Expect = 0.73
Identities = 43/190 (22%), Positives = 67/190 (35%), Gaps = 16/190 (8%)
Query: 402 AELDSVFSSAAT-SSNAYTSTSNASSNVFGTVPVVASAQTQPASSSVPAPFGATPSTNP- 459
A +V SS AT SS+ T+T+ + T P S P+SS + +T P
Sbjct: 1946 ATTPTVTSSKATPSSSPGTATALPALRSTATTPTATSVTPIPSSSLGTTWTRLSQTTTPT 2005
Query: 460 -FVAAAGPSVASSTNPFQTNARGATAATFGTASMSMP-----TGFGTPAPYSLPTSFSG- 512
++ A PS T T T T S++ P T T P + T F+
Sbjct: 2006 ATMSTATPSSTPETAHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTAT 2065
Query: 513 -------SFQQPAFPAQAAFPQQTAFSQQPNGFAAFGQTKPVVTPFGQVAAAGVSSNPFM 565
+ P + + P + P+ T V+T A G + P
Sbjct: 2066 PSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTTTVATGSMATPSS 2125
Query: 566 TGAPTGQFPT 575
+ +G P+
Sbjct: 2126 STQTSGTPPS 2135
>gi|150378545 POM121 membrane glycoprotein (rat)-like [Homo sapiens]
Length = 987
Score = 55.8 bits (133), Expect = 1e-07
Identities = 77/284 (27%), Positives = 113/284 (39%), Gaps = 38/284 (13%)
Query: 313 PKSSSADFGTFNTSQSHQTASAVSKVSTNKAGLQTADKYAALANLDNIFSAGQGGDQGSG 372
PK S FGT NTS S A A S S + TA + + G G
Sbjct: 435 PKQSFL-FGTQNTSPSSPAAPAASSASPMFKPIFTAPP-----------KSEKEGPTPPG 482
Query: 373 FGTTGKAPVGSVVSVPSQSSASSDKY----------AALAELDSVFSSAATSSNAYTSTS 422
T AP S S+P+ +S ++ + A++ F T + A T+T+
Sbjct: 483 PSVTATAPSSS--SLPTTTSTTAPTFQPVFSSMGPPASVPLPAPFFKQTTTPATAPTTTA 540
Query: 423 ---NASSNVFGTVPVVASAQTQPASSSVPA-PFGATPSTNPFVAAAGPSVASSTNPFQTN 478
++ V + SA S+S PA FG ++ V+ + +++ PF
Sbjct: 541 PLFTGLASATSAVAPITSASPSTDSASKPAFGFGINSVSSSSVSTTTSTATAASQPFLFG 600
Query: 479 ARGATAATFGTASMSMPTGFGTPAPYSLPTSFSGSFQQPAFPAQAAFPQQTAFSQQPNGF 538
A A+AA+F T +M FG P +LPT+ + + + P A P TA S F
Sbjct: 601 APQASAASF-TPAMGSIFQFGKPP--ALPTTTTVTTFSQSLP--TAVP--TATSSSAADF 653
Query: 539 AAFGQTKPVVTPFGQVAAAGVSSNPFMTGAPTGQFPTGSSSTNP 582
+ FG T P SN T PT P GSS+ +P
Sbjct: 654 SGFGSTLATSAPATSSQPTLTFSN---TSTPTFNIPFGSSAKSP 694
Score = 47.8 bits (112), Expect = 3e-05
Identities = 99/386 (25%), Positives = 141/386 (36%), Gaps = 68/386 (17%)
Query: 210 APAPQSTATANFANFAHFNSHAA---QNSANADFANFDAFG------QSSGSSNFGGFPT 260
A AP +TA F A S A S + D A+ AFG SS S T
Sbjct: 533 ATAPTTTAPL-FTGLASATSAVAPITSASPSTDSASKPAFGFGINSVSSSSVSTTTSTAT 591
Query: 261 ASHSPF---QPQTTAFRMLSSSCSFGEFTSAFPLQATHSGSAASVNANFAHFDNFPKSSS 317
A+ PF PQ +A + S +F L T + + S + A SS+
Sbjct: 592 AASQPFLFGAPQASAASFTPAMGSIFQFGKPPALPTTTTVTTFSQSLPTA-VPTATSSSA 650
Query: 318 ADFGTFNTSQSHQTASAVSKVSTNKAGLQTADKYAALANLDNIFSAGQGGDQGSGFGTTG 377
ADF F + T + + ++++ L ++ N+ FG++
Sbjct: 651 ADFSGFGS-----TLATSAPATSSQPTLTFSNTSTPTFNIP--------------FGSSA 691
Query: 378 KAPVGSVVSVPSQSSASSDKYAALAELDSVFSSAATSSNAYTSTSNASSNVFGTVPVVAS 437
K+P+ PS A+ AE ++ + S SS FG S
Sbjct: 692 KSPL------PSYPGANPQPAFGAAE-----GQPPGAAKPALTPSFGSSFTFGN-----S 735
Query: 438 AQTQPASSSVPAPFGATPSTNPFVAAAGPSVASSTNPFQTNAR---GATAATFGTASMSM 494
A PA++ PAP ST V A P+ T T++ ATA+ FG + S
Sbjct: 736 AAPAPATAPTPAP----ASTIKIVPAHVPTPIQPTFGGATHSAFGLKATASAFGAPASSQ 791
Query: 495 PTGFGTPAPYSLPTSFSGSFQQPAFPAQAAFPQQTAFSQQPNGFAAFGQTKPVVTPFGQV 554
P G+ A +S + S F QTA S + + FG T P FG
Sbjct: 792 PAFGGSTAVFSFGAATSSGF---------GATTQTASSGSSS--SVFGSTTPSPFTFGGS 840
Query: 555 AA-AGVSSNPFMTGAPTGQFPTGSSS 579
AA AG S P TG+ S
Sbjct: 841 AAPAGSGSFGINVATPGSSATTGAFS 866
Score = 47.8 bits (112), Expect = 3e-05
Identities = 71/304 (23%), Positives = 103/304 (33%), Gaps = 42/304 (13%)
Query: 128 VPPEQAKVVASVHASISGSSASSTSSTPEV--KPLKSLLGDSAPTLHLNKGTPSQSPV-- 183
+P +S A SG ++ +S P +P + S PT ++ G+ ++SP+
Sbjct: 638 LPTAVPTATSSSAADFSGFGSTLATSAPATSSQPTLTFSNTSTPTFNIPFGSSAKSPLPS 697
Query: 184 ---------VGRSQGQQQEKKQFDLLSDLGSDIF----AAPAPQSTATANFANFAHFNSH 230
G ++GQ + L GS AAPAP + T A+
Sbjct: 698 YPGANPQPAFGAAEGQPPGAAKPALTPSFGSSFTFGNSAAPAPATAPTPAPASTIKIVPA 757
Query: 231 AAQNSANADF--ANFDAFGQSSGSSNFGGFPTASHSPFQPQTTAF--------------R 274
F A AFG + +S FG P +S F T F +
Sbjct: 758 HVPTPIQPTFGGATHSAFGLKATASAFGA-PASSQPAFGGSTAVFSFGAATSSGFGATTQ 816
Query: 275 MLSSSCSFGEFTSAFPLQATHSGSAASVNANFAHFDNFPKSSSADFGTFNTSQSHQTASA 334
SS S F S P T GSAA + + SSA G F+ ++A
Sbjct: 817 TASSGSSSSVFGSTTPSPFTFGGSAAPAGSGSFGINVATPGSSATTGAFSFGAGQSGSTA 876
Query: 335 VSKVSTNKAG---LQTADKYAALANLDNIFSAGQGGDQGSGFGTTGKAPVGSVVSVPSQS 391
S T G L T + A F+ G + FG T G P
Sbjct: 877 TSTPFTGGLGQNALGTTGQSTPFA-----FNVGSTTESKPVFGGTATPTFGQNTPAPGVG 931
Query: 392 SASS 395
++ S
Sbjct: 932 TSGS 935
Score = 44.7 bits (104), Expect = 2e-04
Identities = 56/214 (26%), Positives = 78/214 (36%), Gaps = 27/214 (12%)
Query: 384 VVSVPSQSSASSDKYAALAELDSVFSSAATSSNAYTSTSNASSNVFGTVPVVASAQTQPA 443
++ PS A+ K + ++ ATS+ S + S +FGT S+ PA
Sbjct: 399 LIPAPSMVPATDTKAPPTLQAETATKPQATSA---PSPAPKQSFLFGTQNTSPSSPAAPA 455
Query: 444 SSSVPAPF-------------GATPSTNPFVAAAGPSVASSTNPFQTNARGATAATFGTA 490
+SS F G TP P V A PS SS+ P T+ TA TF
Sbjct: 456 ASSASPMFKPIFTAPPKSEKEGPTPP-GPSVTATAPS--SSSLPTTTST---TAPTFQPV 509
Query: 491 SMSMPTGFGTPAPYSLPTSFSGSFQQPAFPAQAAFPQQTAFSQQPNGFAAFGQTKPVVTP 550
SM G PA LP F PA P T + + A P T
Sbjct: 510 FSSM----GPPASVPLPAPFFKQTTTPATAPTTTAPLFTGLASATSAVAPITSASP-STD 564
Query: 551 FGQVAAAGVSSNPFMTGAPTGQFPTGSSSTNPFL 584
A G N + + + T ++++ PFL
Sbjct: 565 SASKPAFGFGINSVSSSSVSTTTSTATAASQPFL 598
>gi|239744074 PREDICTED: ArfGAP with GTPase domain, ankyrin repeat
and PH domain 9 [Homo sapiens]
Length = 684
Score = 55.5 bits (132), Expect = 1e-07
Identities = 32/124 (25%), Positives = 61/124 (49%), Gaps = 7/124 (5%)
Query: 8 KQEEKHLKMLRDMTGLPHNRKCFDCDQRGPTYVNMTVGSFVCTSCSGSLRGLNPP-HRVK 66
+ E L+ +++M G H C DC+ + P + ++ +G +C CSG R RV+
Sbjct: 461 QSEAMALQSIQNMRGNAH---CVDCETQNPKWASLNLGVLMCIECSGIHRSFGTRLSRVR 517
Query: 67 SISMTTFTQQEIEFLQKHGNEVCKQIWLGLFDDRSSAIPDFRDPQKVKE-FLQEKYEKKR 125
S+ + + + + + GNE+ IW G + P + ++ KE +++ KYE+K
Sbjct: 518 SLELDDWPVELRKVMSSIGNELANSIWEG--SSQGQTKPSIKSTREEKEWWIRSKYEEKL 575
Query: 126 WYVP 129
+ P
Sbjct: 576 FLAP 579
>gi|239744064 PREDICTED: ArfGAP with GTPase domain, ankyrin repeat
and PH domain 10 [Homo sapiens]
Length = 684
Score = 55.5 bits (132), Expect = 1e-07
Identities = 32/124 (25%), Positives = 61/124 (49%), Gaps = 7/124 (5%)
Query: 8 KQEEKHLKMLRDMTGLPHNRKCFDCDQRGPTYVNMTVGSFVCTSCSGSLRGLNPP-HRVK 66
+ E L+ +++M G H C DC+ + P + ++ +G +C CSG R RV+
Sbjct: 461 QSEAMALQSIQNMRGNAH---CVDCETQNPKWASLNLGVLMCIECSGIHRSFGTRLSRVR 517
Query: 67 SISMTTFTQQEIEFLQKHGNEVCKQIWLGLFDDRSSAIPDFRDPQKVKE-FLQEKYEKKR 125
S+ + + + + + GNE+ IW G + P + ++ KE +++ KYE+K
Sbjct: 518 SLELDDWPVELRKVMSSIGNELANSIWEG--SSQGQTKPSIKSTREEKEWWIRSKYEEKL 575
Query: 126 WYVP 129
+ P
Sbjct: 576 FLAP 579
>gi|117956373 ArfGAP with GTPase domain, ankyrin repeat and PH
domain 7 [Homo sapiens]
Length = 663
Score = 55.5 bits (132), Expect = 1e-07
Identities = 33/124 (26%), Positives = 63/124 (50%), Gaps = 7/124 (5%)
Query: 8 KQEEKHLKMLRDMTGLPHNRKCFDCDQRGPTYVNMTVGSFVCTSCSGSLRGLNPP-HRVK 66
+ E L+ +++M G H C DC+ + P + ++ +G +C CSG R L RV+
Sbjct: 438 QSEAMALQSIQNMRGNAH---CVDCETQNPKWASLNLGVLMCIECSGIHRSLGTRLSRVR 494
Query: 67 SISMTTFTQQEIEFLQKHGNEVCKQIWLGLFDDRSSAIPDFRDPQKVKE-FLQEKYEKKR 125
S+ + + + + + GN++ IW G R+ P + ++ KE +++ KYE+K
Sbjct: 495 SLELDDWPVELRKVMSSIGNDLANSIWEGSSQGRTK--PTEKSTREEKERWIRSKYEEKL 552
Query: 126 WYVP 129
+ P
Sbjct: 553 FLAP 556
>gi|110227613 centaurin, gamma 3 isoform a [Homo sapiens]
Length = 911
Score = 54.7 bits (130), Expect = 2e-07
Identities = 29/105 (27%), Positives = 51/105 (48%), Gaps = 2/105 (1%)
Query: 26 NRKCFDCDQRGPTYVNMTVGSFVCTSCSGSLRGLNPP-HRVKSISMTTFTQQEIEFLQKH 84
N C DCD P + ++ +G+ +C CSG R L RV+S+ + + + + +
Sbjct: 674 NSFCIDCDAPNPDWASLNLGALMCIECSGIHRHLGAHLSRVRSLDLDDWPPELLAVMTAM 733
Query: 85 GNEVCKQIWLGLFDDRSSAIPDFRDPQKVKEFLQEKYEKKRWYVP 129
GN + +W G S PD +K + +++ KYE+K + P
Sbjct: 734 GNALANSVWEGALGGYSKPGPDACREEK-ERWIRAKYEQKLFLAP 777
>gi|19111150 angiomotin isoform 2 [Homo sapiens]
Length = 675
Score = 54.3 bits (129), Expect = 3e-07
Identities = 54/199 (27%), Positives = 85/199 (42%), Gaps = 14/199 (7%)
Query: 386 SVPSQSSASSDKYAALAELD--SVFSSAATSSNAYTSTSNASSNVFGTVPVVASAQTQPA 443
S ++ S+K AA+A + + ++AAT++ + + ++ + PV +A PA
Sbjct: 454 STQTERGTESNKTAAVAPISVPAPVAAAATAAAITATAATITTTMVAAAPVAVAAAAAPA 513
Query: 444 SSSVPAPFGATPSTNPFVAAAGPSVASSTNPFQTNARGATAATFGTASMSMPTGFGTPAP 503
+++ P+P A + AA P+ A + A A A A+ ++ PAP
Sbjct: 514 AAAAPSPATAAAT----AAAVSPAAAGQIPAAASVASAAAVAPSAAAAAAVQVAPAAPAP 569
Query: 504 YSLPTSFSGSFQQPAFPAQAAFPQQTAFSQQPNGFAAFGQTKPVVTPFGQVAAAGVSSNP 563
P PA AQA+ P QT Q P A T P TP VA A V ++P
Sbjct: 570 VPAPALV--PVPAPA-AAQASAPAQT---QAPTSAPAVAPT-PAPTPTPAVAQAEVPASP 622
Query: 564 FMTGAPTGQFPTGSSSTNP 582
TG + S + NP
Sbjct: 623 -ATGPGPHRLSIPSLTCNP 640
Score = 33.9 bits (76), Expect = 0.43
Identities = 39/157 (24%), Positives = 60/157 (38%), Gaps = 9/157 (5%)
Query: 379 APVGSVVSVPSQSSASSDKYAALAELDSVFSSAATSSNAYTSTSNASSNVFGTVPVVASA 438
APV + + + ++ ++ + V +AA + A + S A++ A+A
Sbjct: 476 APVAAAATAAAITATAATITTTMVAAAPVAVAAAAAPAAAAAPSPATAAATAAAVSPAAA 535
Query: 439 QTQPASSSVPAPFGATPSTNPFV------AAAGPSVASSTNPFQTNARGATAATFGT-AS 491
PA++SV + PS AA P A + P A +A T A
Sbjct: 536 GQIPAAASVASAAAVAPSAAAAAAVQVAPAAPAPVPAPALVPVPAPAAAQASAPAQTQAP 595
Query: 492 MSMPTGFGTPAPYSLPTSFSGSFQQPAFPAQAAFPQQ 528
S P TPAP PT + PA PA P +
Sbjct: 596 TSAPAVAPTPAP--TPTPAVAQAEVPASPATGPGPHR 630
>gi|166064029 angiomotin isoform 1 [Homo sapiens]
Length = 1084
Score = 54.3 bits (129), Expect = 3e-07
Identities = 54/199 (27%), Positives = 85/199 (42%), Gaps = 14/199 (7%)
Query: 386 SVPSQSSASSDKYAALAELD--SVFSSAATSSNAYTSTSNASSNVFGTVPVVASAQTQPA 443
S ++ S+K AA+A + + ++AAT++ + + ++ + PV +A PA
Sbjct: 863 STQTERGTESNKTAAVAPISVPAPVAAAATAAAITATAATITTTMVAAAPVAVAAAAAPA 922
Query: 444 SSSVPAPFGATPSTNPFVAAAGPSVASSTNPFQTNARGATAATFGTASMSMPTGFGTPAP 503
+++ P+P A + AA P+ A + A A A A+ ++ PAP
Sbjct: 923 AAAAPSPATAAAT----AAAVSPAAAGQIPAAASVASAAAVAPSAAAAAAVQVAPAAPAP 978
Query: 504 YSLPTSFSGSFQQPAFPAQAAFPQQTAFSQQPNGFAAFGQTKPVVTPFGQVAAAGVSSNP 563
P PA AQA+ P QT Q P A T P TP VA A V ++P
Sbjct: 979 VPAPALV--PVPAPA-AAQASAPAQT---QAPTSAPAVAPT-PAPTPTPAVAQAEVPASP 1031
Query: 564 FMTGAPTGQFPTGSSSTNP 582
TG + S + NP
Sbjct: 1032 -ATGPGPHRLSIPSLTCNP 1049
Score = 33.9 bits (76), Expect = 0.43
Identities = 39/157 (24%), Positives = 60/157 (38%), Gaps = 9/157 (5%)
Query: 379 APVGSVVSVPSQSSASSDKYAALAELDSVFSSAATSSNAYTSTSNASSNVFGTVPVVASA 438
APV + + + ++ ++ + V +AA + A + S A++ A+A
Sbjct: 885 APVAAAATAAAITATAATITTTMVAAAPVAVAAAAAPAAAAAPSPATAAATAAAVSPAAA 944
Query: 439 QTQPASSSVPAPFGATPSTNPFV------AAAGPSVASSTNPFQTNARGATAATFGT-AS 491
PA++SV + PS AA P A + P A +A T A
Sbjct: 945 GQIPAAASVASAAAVAPSAAAAAAVQVAPAAPAPVPAPALVPVPAPAAAQASAPAQTQAP 1004
Query: 492 MSMPTGFGTPAPYSLPTSFSGSFQQPAFPAQAAFPQQ 528
S P TPAP PT + PA PA P +
Sbjct: 1005 TSAPAVAPTPAP--TPTPAVAQAEVPASPATGPGPHR 1039
>gi|148806877 ankyrin repeat and GTPase domain Arf GTPase activating
protein 11 [Homo sapiens]
Length = 550
Score = 54.3 bits (129), Expect = 3e-07
Identities = 32/124 (25%), Positives = 60/124 (48%), Gaps = 7/124 (5%)
Query: 8 KQEEKHLKMLRDMTGLPHNRKCFDCDQRGPTYVNMTVGSFVCTSCSGSLRGLNPP-HRVK 66
+ E L+ +++M G H C DC+ + P + ++ +G +C CSG R L RV+
Sbjct: 325 QSEAMALQSIQNMRGNSH---CVDCETQNPKWASLNLGVLMCIECSGIHRSLGTRLSRVR 381
Query: 67 SISMTTFTQQEIEFLQKHGNEVCKQIWLGLFDDRSSAIPDFRDPQKVKE-FLQEKYEKKR 125
S+ + + + + + GN++ IW G + P ++ KE +++ KYE K
Sbjct: 382 SLELDDWPVELRKVMSSIGNDLANSIWEG--SSQGQTKPSIESTREEKERWIRSKYEHKL 439
Query: 126 WYVP 129
+ P
Sbjct: 440 FLAP 443
>gi|166851846 centaurin, gamma-like family, member 3 [Homo sapiens]
Length = 686
Score = 54.3 bits (129), Expect = 3e-07
Identities = 32/124 (25%), Positives = 62/124 (50%), Gaps = 7/124 (5%)
Query: 8 KQEEKHLKMLRDMTGLPHNRKCFDCDQRGPTYVNMTVGSFVCTSCSGSLRGLNPP-HRVK 66
+ E L+ +++M G H C DC+ + P + ++ +G +C CSG R L P RV+
Sbjct: 461 QSEAMALQSIQNMRGNAH---CVDCETQNPKWASLNLGVLMCIECSGIHRSLGPHLSRVR 517
Query: 67 SISMTTFTQQEIEFLQKHGNEVCKQIWLGLFDDRSSAIPDFRDPQKVKE-FLQEKYEKKR 125
S+ + + + + + N++ IW G + P + ++ KE +++ KYE+K
Sbjct: 518 SLELDDWPVELRKVMSSIVNDLANSIWEG--SSQGQTKPSEKSTREEKERWIRSKYEEKL 575
Query: 126 WYVP 129
+ P
Sbjct: 576 FLAP 579
>gi|156104893 ArfGAP with GTPase domain, ankyrin repeat and PH
domain 4 [Homo sapiens]
Length = 663
Score = 53.9 bits (128), Expect = 4e-07
Identities = 31/118 (26%), Positives = 60/118 (50%), Gaps = 7/118 (5%)
Query: 14 LKMLRDMTGLPHNRKCFDCDQRGPTYVNMTVGSFVCTSCSGSLRGLNPP-HRVKSISMTT 72
L+ +++M G H C DC+ + P + ++ +G +C CSG R L RV+S+ +
Sbjct: 444 LQSIQNMRGNAH---CVDCETQNPKWASLNLGVLMCIECSGIHRSLGTRLSRVRSLELDD 500
Query: 73 FTQQEIEFLQKHGNEVCKQIWLGLFDDRSSAIPDFRDPQKVKE-FLQEKYEKKRWYVP 129
+ + + + GN++ IW G + P + ++ KE +++ KYE+K + P
Sbjct: 501 WPVELRKVMSSIGNDLANSIWEG--SSQGQTKPSEKSTREEKERWIRSKYEEKLFLAP 556
>gi|214829714 ADP-ribosylation factor GTPase activating protein 3
isoform 2 [Homo sapiens]
Length = 472
Score = 52.8 bits (125), Expect = 9e-07
Identities = 46/173 (26%), Positives = 74/173 (42%), Gaps = 31/173 (17%)
Query: 14 LKMLRDMTGLPHNRKCFDCDQRGPTYVNMTVGSFVCTSCSGSLRGLNPP-HRVKSISM-T 71
L + + + +P N+ CFDC + P++ ++T G F+C CSGS R L ++S + +
Sbjct: 10 LTIFKRLRSVPTNKVCFDCGAKNPSWASITYGVFLCIDCSGSHRSLGVHLSFIRSTELDS 69
Query: 72 TFTQQEIEFLQKHGNEVCKQIWLGLFDDRSSAIPDFRDPQKVKEFLQEKYEKKRWYVPPE 131
++ ++ +Q GN +WL S +P P K ++F +V PE
Sbjct: 70 NWSWFQLRCMQVGGN--ASALWLD-----SCVVPPLSPPPKEEDFFAS-------HVSPE 115
Query: 132 QAKVVASVHASISGSSASSTSSTPEVKPLKSLLGDSAPTLHLNKGTPSQSPVV 184
V + AS +S TS E TL N+G Q P V
Sbjct: 116 ---VSDTAWASAIAEPSSLTSRPVET------------TLENNEGGQEQGPSV 153
>gi|117956371 ArfGAP with GTPase domain, ankyrin repeat and PH
domain 8 [Homo sapiens]
Length = 663
Score = 52.8 bits (125), Expect = 9e-07
Identities = 31/124 (25%), Positives = 61/124 (49%), Gaps = 7/124 (5%)
Query: 8 KQEEKHLKMLRDMTGLPHNRKCFDCDQRGPTYVNMTVGSFVCTSCSGSLRGLNPP-HRVK 66
+ E L+ +++M G H C DC+ + P + ++ +G +C CSG L RV+
Sbjct: 438 QSEAMALQSIQNMRGNAH---CVDCETQNPKWASLNLGVLMCIECSGIHHSLGTRLSRVR 494
Query: 67 SISMTTFTQQEIEFLQKHGNEVCKQIWLGLFDDRSSAIPDFRDPQKVKE-FLQEKYEKKR 125
S+ + + + + + GN++ IW G + P + ++ KE +++ KYE+K
Sbjct: 495 SLELDDWPVELRKVMSSIGNDLANSIWEG--SSQGQTKPSEKSTREEKERWIRSKYEEKL 552
Query: 126 WYVP 129
+ P
Sbjct: 553 FLAP 556
>gi|167736355 mucin 4 isoform a [Homo sapiens]
Length = 5284
Score = 52.0 bits (123), Expect = 2e-06
Identities = 107/471 (22%), Positives = 175/471 (37%), Gaps = 53/471 (11%)
Query: 128 VPPEQAKVVASVHASISGSSASSTSSTPEVKPLKSLLGDSAPTLHLNKGTPSQSPVVGRS 187
+P A V++ HA+ + +S+ ST + PL SA T G + PV S
Sbjct: 1985 LPVTDASSVSTGHATPLPVTDTSSVSTGQATPLPVTSLSSAST-----GDTTPLPVTDTS 2039
Query: 188 QGQQQEKKQFDLLSDLGSDIFAAPAPQSTATANFANFAHFNSHAAQNSANADFANFDAFG 247
+ + S L S P + + A+ H ++++ + +
Sbjct: 2040 SASTGQDTPLPVTS-LSSVSTGDTTPLPVTSPSSASTGHATPLLVTDASSVSTGHATSLL 2098
Query: 248 QSSGSSNFGGFPTASHSPFQPQTTAFRMLSSSCSFGEFTSAFPLQATHSGSAASVNANFA 307
+ SS G TA H +SS S G+ T PL T SA++
Sbjct: 2099 VTDASSVSTGHATALHVTD----------ASSLSTGDTT---PLPVTSPSSASTG----- 2140
Query: 308 HFDNFPKSSSADFGTFNTSQSHQTASAVSKVSTNKAGLQTADKYAALANLDNIFSAGQGG 367
D P + T + S H T+ V+ S+ G +A + + SA G
Sbjct: 2141 --DTTPLPVT---DTSSVSTGHATSLPVTDTSSASTG------HATSLPVTDTSSASTGH 2189
Query: 368 DQGSGFGTTGKAPVGSVVSVPSQSSASSDKYAALAELDSVFSSAATSSNA---YTSTSNA 424
T A G +P S +S+ A+ L + SSA+T TS S+A
Sbjct: 2190 ATPLPVTDTSSASTGQATPLPVTSPSSASTGHAIPLLVTDTSSASTGQATPLPVTSLSSA 2249
Query: 425 SSNVFGTVPVV-ASAQTQPASSSVPAPFGATPSTNPF--VAAAGPSVASSTNPFQTNARG 481
S+ +PV AS+ + ++S+P ++ ST + PS AS+ + +
Sbjct: 2250 STGDTTPLPVTDASSVSTGHATSLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLHVTD 2309
Query: 482 ATAATFG-------TASMSMPTGFGTPAPYSLPTSFSGSFQQPAFPAQA---AFPQQTAF 531
A++A+ G T+ S TG TP P + P+S S P A + T
Sbjct: 2310 ASSASTGHATPLPVTSLSSASTGDTTPLPVTSPSSASTGHATPLHVTDASSVSTGDTTPL 2369
Query: 532 SQQPNGFAAFGQTKPVVTPFGQVAAAGVSSNPFMTGAPTGQFPTGSSSTNP 582
+ A+ G T P+ P ++A + T TG ++ P
Sbjct: 2370 PVTSSSSASSGHTTPL--PVTDASSASTGDTTPLPVTDTSSASTGHATHLP 2418
Score = 51.6 bits (122), Expect = 2e-06
Identities = 98/472 (20%), Positives = 171/472 (36%), Gaps = 70/472 (14%)
Query: 143 ISGSSASSTSST-PEVKPLKSLLGDSA-PTLHLNKGT--PSQSPVVGRSQGQQQEKKQFD 198
++G+ ++ T+ T P V S +G+ PT + + T P + ++Q Q+ +
Sbjct: 517 VTGNPSTGTAGTIPRVPSKVSAIGEPGEPTTYSSHSTTLPKTTGAGAQTQWTQETGTTGE 576
Query: 199 LLSDLGSDIFAAPAPQSTATANFANFAHFNSHAAQNSANADFANFDAFGQSSGSSNFGGF 258
L L S ++ TAT+ ++ + H +Q A N +S S
Sbjct: 577 AL--LSSPSYSVTQMIKTATSPSSS-PMLDRHTSQQITTAPSTNHSTIHSTSTSPQESPA 633
Query: 259 PTASHSPFQPQTTAFRMLSSSCSFGEFTSAFPLQATHSGSAASVNANFAHFDNFPKSSSA 318
+ PQTT + S S T + ++ + D S++
Sbjct: 634 VSQRGHTQAPQTTQESQTTRSVSPMTDTKTVTTPGSSFTASGHSPSEIVPQDAPTISAAT 693
Query: 319 DFGTFNTSQSHQTASAVSKVSTNKAGLQTADKYAALANLDNIFSAGQGGDQGSGFGTTGK 378
F T H T + + AL + A G G+ TG
Sbjct: 694 TFAPAPTGDGHTTQAPTT----------------ALQAAPSSHDATLGPSGGTSLSKTGA 737
Query: 379 APVG-SVVSVPSQSSASSDKYAALAELDSVFSSAATSSNAYTSTSNASSNVFGTVPVVAS 437
+ SVVS P +A D+ +AA + ++ AS + P +
Sbjct: 738 LTLANSVVSTPGGPEGQWTSASASTSPDT---AAAMTHTHQAESTEASGQTQTSEPASSG 794
Query: 438 AQTQPASSSVPAPFGA---TPSTNPFVAAAGPSVASSTNPFQTN--------------AR 480
++T A ++ P+ GA TPS + ++ +G + S+NP + + +
Sbjct: 795 SRTTSAGTATPSSSGASGTTPSGSEGISTSGETTRFSSNPSRDSHTTQSTTELLSASASH 854
Query: 481 GATAATFGTASMSMPTGF----------GTPAPYSLPTSFSGSFQQPAFPAQAAFPQQTA 530
GA + G AS +P F G P S PTS S S Q+ A ++ A Q+T
Sbjct: 855 GAIPVSTGMASSIVPGTFHPTLSEASTAGRPTGQSSPTSPSASPQETAAISRMAQTQRTR 914
Query: 531 FSQQPNGFAAFGQTKPVVTPFGQVAAAGVSSNPFMTGAPTGQFPTGSSSTNP 582
S+ + ++ A +++ F T PT T + T+P
Sbjct: 915 TSRGSD----------------TISLASQATDTFSTVPPTPPSITSTGLTSP 950
Score = 50.4 bits (119), Expect = 4e-06
Identities = 93/419 (22%), Positives = 160/419 (38%), Gaps = 52/419 (12%)
Query: 142 SISGSSASSTSSTPEVKPLKSLLGDS-AP-TLHLNKGTPSQSPVVGRSQGQQQEKKQFDL 199
S + S+ STS++P+ P S G + AP T ++ T S SP+ ++ F
Sbjct: 615 STNHSTIHSTSTSPQESPAVSQRGHTQAPQTTQESQTTRSVSPMTD-TKTVTTPGSSFTA 673
Query: 200 LSDLGSDIFAAPAPQSTATANFANFAHFNSHAAQ---NSANADFANFDA-FGQSSGSS-- 253
S+I AP +A FA + H Q + A ++ DA G S G+S
Sbjct: 674 SGHSPSEIVPQDAPTISAATTFAPAPTGDGHTTQAPTTALQAAPSSHDATLGPSGGTSLS 733
Query: 254 NFGGFPTASHSPFQPQTTAFRMLSSSCSFGEFTSAFPLQATHSGSAASVNANFAHFDNFP 313
G A+ P + S+S S T+A TH+ A S A+ + P
Sbjct: 734 KTGALTLANSVVSTPGGPEGQWTSASASTSPDTAA---AMTHTHQAESTEASGQTQTSEP 790
Query: 314 KSSSA-----------DFGTFNTSQSHQTASAVSKVSTNKAGLQTADKYAALANLDNIFS 362
SS + G T+ S + S +T + + D + + + + +
Sbjct: 791 ASSGSRTTSAGTATPSSSGASGTTPSGSEGISTSGETTRFSSNPSRDSHTTQSTTELLSA 850
Query: 363 AGQGGDQGSGFG-----------------TTGKAPVGSVVSVPSQSSASSDKYAALAELD 405
+ G G +T P G S P+ SAS + AA++ +
Sbjct: 851 SASHGAIPVSTGMASSIVPGTFHPTLSEASTAGRPTGQ--SSPTSPSASPQETAAISRMA 908
Query: 406 SVFSSAATSSNAYTSTSNASSNVFGTVPVVASAQTQPASSSVPAPFGATPSTNPFVAAAG 465
+ + + S ++ +++ F TVP + T S+ + +P T + +P +
Sbjct: 909 QTQRTRTSRGSDTISLASQATDTFSTVPPTPPSIT---STGLTSPQTETHTLSPSGSGKT 965
Query: 466 PSVASSTNPFQTNARGATAATFG-------TASMSMPTGFGTPAPYSLPTSFSGSFQQP 517
+ A +N A++A+ G T + S+ TG TP P + P+S S P
Sbjct: 966 FTTALISNATPLPVTYASSASTGHTTPLHVTDASSVSTGHATPLPVTSPSSVSTGHTTP 1024
Score = 46.2 bits (108), Expect = 8e-05
Identities = 116/519 (22%), Positives = 189/519 (36%), Gaps = 81/519 (15%)
Query: 128 VPPEQAKVVASVHASISGSSASSTSSTPEVKPLKSLLGDSAPTLHLNKGTPSQSPVVGRS 187
+P ++ HA+ +++S++ST + PL SA T G + PV S
Sbjct: 2561 LPVTDTSAASTGHATPLPVTSTSSASTGDTTPLPVTDTYSAST-----GQATPLPVTDTS 2615
Query: 188 QGQQQEKKQFDLL-SDLGSDIFAAPAP---QSTATANFANFAHFNSHAAQNSANAD-FAN 242
+ + + S A P P S+ + A H S ++ ++ +
Sbjct: 2616 SASTGDTTPLPVTDTSSASTGHATPLPVTNTSSVSTGHATPLHVTSPSSASTGHTTPLPV 2675
Query: 243 FDAFGQSSGSSNFGGFPTASHSPFQPQTTAFRM-LSSSCSFGEFTSAFPLQATHSGSAAS 301
DA S+G + AS S F T+ + + SS S G T PL T + S ++
Sbjct: 2676 TDASSVSTGHATSLPVTDAS-SVFTGHATSLPVTIPSSASSGHTT---PLPVTDASSVST 2731
Query: 302 VNANFAHFDNFPKSSSADFGT-----------FNTSQSHQTASAVSKVSTNKAG----LQ 346
H + P + ++ T + S H T ++ +S+ G L
Sbjct: 2732 -----GHATSLPVTDASSVSTGHATPLPVTDASSVSTGHATPLPLTSLSSVSTGDTTPLP 2786
Query: 347 TADKYAALAN------LDNIFSAGQGGDQGSGFGTTGKAPVGSVVSVPSQSSASSDKYAA 400
D +A + ++ S G T A G S+P ++S+ A
Sbjct: 2787 VTDTSSASTGQATPLPVTSLSSVSTGDTTPLPVTDTSSASTGHATSLPVTDTSSASTGHA 2846
Query: 401 LAELDSVFSSAATSSNA---YTSTSNASSNVFGTVPVVASAQ-----------TQPASSS 446
D+ SSA+T T TS+AS ++PV ++ T P+S+S
Sbjct: 2847 TPLPDTDTSSASTGHATLLPVTDTSSASIGHATSLPVTDTSSISTGHATPLHVTSPSSAS 2906
Query: 447 ----VPAPFGATPS-----TNPFVAAAGPSVASSTNPFQTNARGATAATFG-------TA 490
P P T S NP + PS AS+ + ++A+ G T+
Sbjct: 2907 TGHATPLPVTDTSSASTGHANP-LHVTSPSSASTGHATPLPVTDTSSASTGHATPLPVTS 2965
Query: 491 SMSMPTGFGTPAPYSLPTSFSGSFQQP---AFPAQAAFPQQTAFSQQPNGFAAFGQTKPV 547
S+ TG TP P + P+S S P + A+ Q TA A+ G T P+
Sbjct: 2966 LSSVSTGDTTPLPVTSPSSASTGHTTPLPVTDTSSASTGQATALPVTSTSSASTGDTTPL 3025
Query: 548 ------VTPFGQVAAAGVSSNPFMTGAPTGQFPTGSSST 580
GQ V+S ++ T P S S+
Sbjct: 3026 PVTDTSSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSS 3064
Score = 45.8 bits (107), Expect = 1e-04
Identities = 80/328 (24%), Positives = 124/328 (37%), Gaps = 44/328 (13%)
Query: 278 SSCSFGEFTSAFPLQATHSGSAASVNANFAHFDNFPKSSSADFGTFNTSQSHQTASAVSK 337
SS S G+ T PL T + SA++ H P + ++ T +T T V+
Sbjct: 3751 SSASTGDTT---PLPVTDTSSAST-----RHATPLPVTDTSSASTDDT-----TRLPVTD 3797
Query: 338 VSTNKAGLQTADKYAALANLDNIFSAGQGGDQGSGFGTTGKAPVGSVVSVP--SQSSASS 395
VS+ G +A + + SA G T G S+P S+SSAS+
Sbjct: 3798 VSSASTG------HATPLPVTSTSSASTGDTTPLPVTDTSSVSTGHATSLPVTSRSSAST 3851
Query: 396 DKYAALAELD-SVFSSAATSSNAYTSTSNASSNVFGTVPVVASAQTQ-------PASSSV 447
L D S S+ + TSTS+ S+ +PV + + P +S+
Sbjct: 3852 GHATPLPVTDTSSVSTGHATPLPVTSTSSVSTGHATPLPVTSPSSASTGHATPVPVTSTS 3911
Query: 448 PAPFGAT---PSTNPFVAAAGPSVASSTNPFQTNARGATAATFGTASMSMPTGFGTPAPY 504
A G T P TN + G + + +RG T+ T + S TG TP P
Sbjct: 3912 SASTGDTTPLPVTNASSLSTGHATPLHVTSPSSASRGDTSTLPVTDASSASTGHATPLPL 3971
Query: 505 SLPTSFSGSFQQP---AFPAQAAFPQQTAFSQQPNGFAAFGQTKPVVTPFGQVAAAGVSS 561
+ +S S P + A+ Q T + G T P+ A++G ++
Sbjct: 3972 TSLSSVSTGDTTPLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLPVTIPSSASSGHTT 4031
Query: 562 NPFMT---------GAPTGQFPTGSSST 580
+ +T G P T S+ST
Sbjct: 4032 SLPVTDASSVSTGHGTPLPVTSTSSAST 4059
Score = 44.7 bits (104), Expect = 2e-04
Identities = 85/387 (21%), Positives = 135/387 (34%), Gaps = 50/387 (12%)
Query: 142 SISGSSASSTSSTPEVKPLKSLLGDSAP-----TLHLNKGTPSQSPVVGRSQGQQQEKKQ 196
S+S +S T P P + GD+ P ++ G + V S +
Sbjct: 1317 SLSSASTGDTMPLPVTSPSSASTGDTTPLPVTDASSVSTGHTTPLHVTDASSASTGQATP 1376
Query: 197 FDLLSDLGSDIFAAPAPQSTATANFANFAHFNSHAAQNSANADFANFDAFGQSSGSSNFG 256
+ S L S P + + A+ H ++++A + + SS
Sbjct: 1377 LPVTS-LSSVSTGDTTPLPVTSPSSASTGHATPLLVTDTSSASTGHATPLPVTDASS--- 1432
Query: 257 GFPTASHSPFQPQTTAFRMLSSSCSFGEFTSAFPLQATHSGSAASVNANFAHFDNFPKSS 316
+ H+ P T + S+ S G T PL T + SA++ A + S
Sbjct: 1433 --VSTDHATSLPVT-----IPSAASTGHTT---PLPVTDTSSASTGQATSLLVTDTSSVS 1482
Query: 317 SADF------GTFNTSQSHQTASAVSKVSTNKAGLQTADKYAALANLDNIFSAGQGGDQG 370
+ D T + S H T V+ S+ G T +L++
Sbjct: 1483 TGDTTPLPVTSTSSASTGHVTPLHVTSPSSASTGHATPLPVTSLSSAST----------- 1531
Query: 371 SGFGTTGKAPVGSVVSVPSQSSASSDKYAALAELDSVFSSAATSSNAYTSTSNASSNVFG 430
G T PV S PS +S + + SV S+ T+ TS S+AS+
Sbjct: 1532 ---GDTMPLPVTS----PSSASTGDTTPLPVTDASSV-STGHTTPLPVTSPSSASTGHTT 1583
Query: 431 TVPVVASAQTQPASSSVPAPFGATPSTNPFVAAAGPSVASSTNPFQTNARGATAATFGTA 490
+PV T AS P P T+P A+ G + + + G T T
Sbjct: 1584 PLPVT---DTSSASKGDTTPL---PVTSPSSASTGHTTPLPVTDTSSASTGDTTPLPVTN 1637
Query: 491 SMSMPTGFGTPAPYSLPTSFSGSFQQP 517
+ S+ TG TP + P+S S P
Sbjct: 1638 ASSLSTGHATPLHVTSPSSASTGHATP 1664
Score = 44.7 bits (104), Expect = 2e-04
Identities = 99/469 (21%), Positives = 165/469 (35%), Gaps = 65/469 (13%)
Query: 128 VPPEQAKVVASVHASISGSSASSTSSTPEVKPLKSLLGDSAPTLH-----------LNKG 176
+P A V++ HA+ + +S+ ST PL S T H ++ G
Sbjct: 2721 LPVTDASSVSTGHATSLPVTDASSVSTGHATPLPVTDASSVSTGHATPLPLTSLSSVSTG 2780
Query: 177 TPSQSPVVGRSQGQQQEKKQFDLLSDLGSDIFAAPAPQSTATANFANFAHFNSHAAQNSA 236
+ PV S + + S L S P + A+ H S +++
Sbjct: 2781 DTTPLPVTDTSSASTGQATPLPVTS-LSSVSTGDTTPLPVTDTSSASTGHATSLPVTDTS 2839
Query: 237 NADFANFDAFGQSSGSSNFGGFPTASHSPFQPQTTAFRMLSSSCSFGEFTSAFPLQATHS 296
+A + + SS G H+ P T +SS S G TS L T +
Sbjct: 2840 SASTGHATPLPDTDTSSASTG-----HATLLPVTD-----TSSASIGHATS---LPVTDT 2886
Query: 297 GSAASVNANFAHFDNFPKSSSADFGTFNTSQSHQTASAVSKVSTNKAGLQTADKYAALAN 356
S ++ +A H + P S+S H T V+ S+ G +A +
Sbjct: 2887 SSISTGHATPLHVTS-PSSAST---------GHATPLPVTDTSSASTG------HANPLH 2930
Query: 357 LDNIFSAGQGGDQGSGFGTTGKAPVGSVVSVPSQSSASSDKYAALAELDSVFSSAATSSN 416
+ + SA G T A G +P S +S S+ T+
Sbjct: 2931 VTSPSSASTGHATPLPVTDTSSASTGHATPLPVTSLSS-------------VSTGDTTPL 2977
Query: 417 AYTSTSNASSNVFGTVPVVASAQTQPASSSVPAPFGATPSTNPFVAAAGPSVASSTNPFQ 476
TS S+AS+ +PV ++ ++ A P T+ A+ G +
Sbjct: 2978 PVTSPSSASTGHTTPLPVTDTSSASTGQAT------ALPVTSTSSASTGDTTPLPVTDTS 3031
Query: 477 TNARGATAATFGTASMSMPTGFGTPAPYSLPTSFSGSFQQPAF---PAQAAFPQQTAFSQ 533
+ + G T+ S+ TG TP P + P+S S P + A+ Q T
Sbjct: 3032 SASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDASSASTGQATPLPV 3091
Query: 534 QPNGFAAFGQTKPVVTPFGQVAAAGVSSNPFMTGAPTGQFPTGSSSTNP 582
+ G T P+ A+ G +++ +T T TG +++ P
Sbjct: 3092 TSLSSVSTGDTTPLPVTSPSSASTGHATSLPVT--DTSSASTGDTTSLP 3138
Score = 44.3 bits (103), Expect = 3e-04
Identities = 72/299 (24%), Positives = 107/299 (35%), Gaps = 26/299 (8%)
Query: 277 SSSCSFGEFTSAFPLQATHSGSAASVNANFAHFDNFPKSSSADFG------TFNTSQSHQ 330
+SS S G+ TS L T + SA + + + SS+ D T + S H
Sbjct: 3126 TSSASTGDTTS---LPVTDTSSAYTGDTTSLPVTDTSSSSTGDTTPLLVTETSSVSTGHA 3182
Query: 331 TASAVSKVSTNKAGLQTADKYAALANLDNIFSAGQGGDQGSGFGTTGKAPVGSVVSVP-- 388
T V+ S+ G +A ++ + SA G T G +P
Sbjct: 3183 TPLLVTDASSASTG------HATPLHVTSPSSASTGDTTPVPVTDTSSVSTGHATPLPVT 3236
Query: 389 SQSSASSDKYAALAELDSVFSSAATSSNAYTSTSNASSNVFGTVPVVASAQTQPASSSVP 448
SSAS+ L D SSA+T +N SS G + AS+
Sbjct: 3237 GLSSASTGDTTRLPVTD--ISSASTGQATPLPVTNTSSVSTGDTMPLPVTSPSSASTGHA 3294
Query: 449 APFGATPSTNPFVAAAGPSVASSTNPFQTNARGATAATFGTASMSMPTGFGTPAPYSLPT 508
P T +++ A P +ST+ T G T T + S TG TP P + P+
Sbjct: 3295 TPLPVTSTSSASTGHATPVPVTSTSSAST---GHTTPLPVTDTSSASTGDTTPLPVTSPS 3351
Query: 509 SFSGSFQQP---AFPAQAAFPQQTAFSQQPNGFAAFGQTKPV-VTPFGQVAAAGVSSNP 563
S S P P+ A+ + A+ G P+ VT V+ + P
Sbjct: 3352 SASTGHTTPLHVTIPSSASTGDTSTLPVTGASSASTGHATPLPVTDTSSVSTGHATPLP 3410
Score = 43.5 bits (101), Expect = 5e-04
Identities = 114/507 (22%), Positives = 177/507 (34%), Gaps = 70/507 (13%)
Query: 128 VPPEQAKVVASVHASISGSSASSTSSTPEVKPLKSLLGDSAPTLHLNKGTPSQSPVVGRS 187
+P ++ HA+ + +S++ST + PL SA T H + +
Sbjct: 2177 LPVTDTSSASTGHATPLPVTDTSSASTGQATPLPVTSPSSASTGHAIPLLVTDTSSASTG 2236
Query: 188 QGQQQEKKQFDLLSDLGSDIFAAPAPQSTATANFANFAHFNSHAAQNSANADFANFDAFG 247
Q ++ L S P A+ + H S + ++ +
Sbjct: 2237 QATPLP------VTSLSSASTGDTTPLPVTDASSVSTGHATSLPVTSLSSVSTGDTTPLP 2290
Query: 248 QSSGSSNFGGFPTASH-----SPFQPQTTAFRMLS-SSCSFGEFTSAFPLQATHSGSAAS 301
+S SS G T H S T + S SS S G+ T PL T SA++
Sbjct: 2291 VTSPSSASTGHATPLHVTDASSASTGHATPLPVTSLSSASTGDTT---PLPVTSPSSAST 2347
Query: 302 VNANFAHFDNFPKSSSADF------GTFNTSQSHQTASAVSKVSTNKAG----LQTADKY 351
+A H + S+ D + + S H T V+ S+ G L D
Sbjct: 2348 GHATPLHVTDASSVSTGDTTPLPVTSSSSASSGHTTPLPVTDASSASTGDTTPLPVTD-- 2405
Query: 352 AALANLDNIFSAGQGGDQGSGFGTTGKAPVGSVVS----------VPSQSSASSDKYAAL 401
+ A+ + G + G T + PV +V S V S SSAS+ L
Sbjct: 2406 TSSASTGHATHLPVTGLSSASTGDTTRLPVTNVSSASTGHATPLPVTSTSSASTGDTTPL 2465
Query: 402 AELD-SVFSSAATSSNAYTSTSNASSNVFGTVPVVASAQTQPASSSV----PAPFGATPS 456
D S S+ T+ T S+ S+ +PV T P+S+S P P TPS
Sbjct: 2466 PGTDTSSVSTGHTTPLLVTDASSVSTGDTTRLPV-----TSPSSASTGHTTPLPVTDTPS 2520
Query: 457 -----TNPFVAAAGPSVASS-------TNPFQTNARGATAATFGTASMSMPTGFGTPAPY 504
T P S+++ T+P + AT+ T + + TG TP P
Sbjct: 2521 ASTGDTTPLPVTNASSLSTRHATSLHVTSPSSASTGHATSLPV-TDTSAASTGHATPLPV 2579
Query: 505 SLPTSFSGSFQQP---AFPAQAAFPQQTAFSQQPNGFAAFGQTKPVVTPFGQVAAAG--- 558
+ +S S P A+ Q T A+ G T P+ A+ G
Sbjct: 2580 TSTSSASTGDTTPLPVTDTYSASTGQATPLPVTDTSSASTGDTTPLPVTDTSSASTGHAT 2639
Query: 559 ----VSSNPFMTGAPTGQFPTGSSSTN 581
+++ TG T T SS +
Sbjct: 2640 PLPVTNTSSVSTGHATPLHVTSPSSAS 2666
Score = 42.7 bits (99), Expect = 0.001
Identities = 97/421 (23%), Positives = 149/421 (35%), Gaps = 38/421 (9%)
Query: 128 VPPEQAKVVASVHASISGSSASSTSSTPEVKPLKSLLGDSAPTLHLNKGTPSQSPVVGRS 187
+P A V++ H + + +S++ST + PL S T G + PV S
Sbjct: 1345 LPVTDASSVSTGHTTPLHVTDASSASTGQATPLPVTSLSSVST-----GDTTPLPVTSPS 1399
Query: 188 QGQQQEKKQFDLLSDLGSDIFAAPAPQSTATANFANFAHFNS------HAAQNSANADFA 241
L++D S P A+ + H S AA
Sbjct: 1400 SASTGHATPL-LVTDTSSASTGHATPLPVTDASSVSTDHATSLPVTIPSAASTGHTTPLP 1458
Query: 242 NFDAFGQSSGSSNFGGFPTASHSPFQPQTTAFRMLS-SSCSFGEFTSAFPLQATHSGSAA 300
D S+G + T + S TT + S SS S G T PL T SA+
Sbjct: 1459 VTDTSSASTGQAT-SLLVTDTSSVSTGDTTPLPVTSTSSASTGHVT---PLHVTSPSSAS 1514
Query: 301 SVNANFAHFDNFPKSSSADFGTF--NTSQSHQTASAVSKVSTNKAGLQTADKYAALANLD 358
+ +A + +S+ D + S T T+ + + T + +
Sbjct: 1515 TGHATPLPVTSLSSASTGDTMPLPVTSPSSASTGDTTPLPVTDASSVSTG--HTTPLPVT 1572
Query: 359 NIFSAGQGGDQGSGFGTTGKAPVGSVVSVP--SQSSASSDKYAALAELDSVFSSAATSSN 416
+ SA G T A G +P S SSAS+ L D+ SSA+T
Sbjct: 1573 SPSSASTGHTTPLPVTDTSSASKGDTTPLPVTSPSSASTGHTTPLPVTDT--SSASTGDT 1630
Query: 417 AYTSTSNASSNVFG--TVPVVASAQTQPASSSVPAPFGATPSTNPFVAA----AGPSVAS 470
+NASS G T V S + + P P +T S + A G S A+
Sbjct: 1631 TPLPVTNASSLSTGHATPLHVTSPSSASTGHATPLPVTSTSSASTGHATPLPVTGLSSAT 1690
Query: 471 STNPFQTNARGATAATFGTAS-------MSMPTGFGTPAPYSLPTSFSGSFQQPAFPAQA 523
+ + + ++A+ G A+ S+ TG TP P + P+S S P A
Sbjct: 1691 TDDTTRLPVTDVSSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHASPLLVTDA 1750
Query: 524 A 524
+
Sbjct: 1751 S 1751
Score = 42.7 bits (99), Expect = 0.001
Identities = 103/453 (22%), Positives = 150/453 (33%), Gaps = 75/453 (16%)
Query: 144 SGSSASSTSSTPEVKPLKSLLGDSAPTLHL------NKGTPSQSPVVGRSQGQQQEKKQF 197
S +S T+ P P + G + P LH+ + G S PV G S
Sbjct: 3335 SSASTGDTTPLPVTSPSSASTGHTTP-LHVTIPSSASTGDTSTLPVTGASSA-------- 3385
Query: 198 DLLSDLGSDIFAAPAP----QSTATANFANFAHFNSHAAQNSANADFANFDAFGQSSGSS 253
S A P P S +T + + + DA S+G +
Sbjct: 3386 -------STGHATPLPVTDTSSVSTGHATPLPVTSLSSVSTGDTTPLPVTDASSASTGQA 3438
Query: 254 NFGGFPTASHSPFQPQTTAFRMLS--SSCSFGEFTSAFPLQATHSGSAAS---------- 301
P S S T +++ SS S G T PL T + SA++
Sbjct: 3439 T--PLPVTSLSSVSTGDTTPLLVTDASSVSTGHAT---PLPVTDTSSASTGDTTRLPVTD 3493
Query: 302 -VNANFAHFDNFPKSSSADFGTFNTS-------QSHQTASAVSKVSTNKAGLQTADKYAA 353
+A+ P +S + T +T+ S T A T+ + T D
Sbjct: 3494 TSSASTGQATPLPVTSLSSVSTGDTTPLLVTDASSVSTGHATPLPVTDTSSASTGDTTRL 3553
Query: 354 LANLDNIFSAGQGGD------QGSGFGTTGKAPVGSVVSVP----------SQSSASSDK 397
+ S GQ S G T PV S SV S SSAS+
Sbjct: 3554 PVTDTSSASTGQATPLPVTIPSSSSSGHTTPLPVTSTSSVSTGHVTPLHVTSPSSASTGH 3613
Query: 398 YAALAELDSVFSSAATSSNAYTSTSNASSNVFGTVPVVASAQTQPASSSVPAPFGATPST 457
L + SSA+T ++ASS G + AS+ P T ++
Sbjct: 3614 VTPLPVTST--SSASTGHATPLLVTDASSVSTGHATPLPVTDASSASTGDTTPLPVTDTS 3671
Query: 458 NPFVAAAGPSVASSTNPFQTNARGATAATFGTASMSMPTGFGTPAPYSLPTSFSGSFQQP 517
+ A P +S + T G T T + S TG TP P ++P+S S P
Sbjct: 3672 SASTGQATPLPVTSLSSVST---GDTTPLPVTDASSASTGHATPLPVTIPSSVSTGDTMP 3728
Query: 518 ---AFPAQAAFPQQTAFSQQPNGFAAFGQTKPV 547
P+ A+ T A+ G T P+
Sbjct: 3729 LPVTSPSSASTGHATPLPVTGLSSASTGDTTPL 3761
Score = 40.8 bits (94), Expect = 0.003
Identities = 56/262 (21%), Positives = 91/262 (34%), Gaps = 59/262 (22%)
Query: 368 DQGSGFGTTGKAPVGSVVSVPS----------------QSSASSDKYAALAELDSVFSSA 411
++ S GT PV S VS+ + +SASS + + + S
Sbjct: 152 EETSTAGTESSTPVTSAVSITAGQEGQSRTTSWRTSIQDTSASSQNHWTRSTQTTRESQT 211
Query: 412 ATSSNAYTSTSNASSNVFGTVPVVASAQTQPASSSVPAPFGATPSTNPFVAAAGPSVASS 471
+T ++ TST + S +V V S +T P+ + +T+ + S+ +S
Sbjct: 212 STLTHRTTSTPSFSPSVHNVTGTV-SQKTSPSGET---------ATSSLCSVTNTSMMTS 261
Query: 472 TNPFQTNARGATAATFGTASMSMPTGFGTPAPYSLPTSFSGSFQQPAFPAQAAFPQQTAF 531
T + G+T G S TG P + +F Q PA ++ + TAF
Sbjct: 262 EKITVTTSTGSTLGNPGETSSVPVTGSLMPVTSAALVTFDPEGQSPATFSRTSTQDTTAF 321
Query: 532 SQ-------------------------------QPNGFAAFGQTKPVVTPFGQVAAAGVS 560
S+ P+GF G P G+ + S
Sbjct: 322 SKNHQTQSVETTRVSQINTLNTLTPVTTSTVLSSPSGFNPSGTVSQETFPSGETTTSSPS 381
Query: 561 --SNPFMTGAPTGQFPTGSSST 580
SN F+ + + PT ST
Sbjct: 382 SVSNTFLVTSKVFRMPTSRDST 403
Score = 40.8 bits (94), Expect = 0.003
Identities = 86/385 (22%), Positives = 138/385 (35%), Gaps = 26/385 (6%)
Query: 137 ASVHASISGSSASSTSSTPEVKPLKSLLGDSAPTLHLNKGTPSQSPVVGRSQGQQQEKKQ 196
+S H + +++S+ ST V PL SA T H+ TP PV S
Sbjct: 3578 SSGHTTPLPVTSTSSVSTGHVTPLHVTSPSSASTGHV---TPL--PVTSTSSASTGHATP 3632
Query: 197 FDLLSDLGSDIFAAPAPQSTATANFANFAHFNSHAAQNSANADFANFDAFGQSSGSSNFG 256
L++D S P A+ A+ ++++A +S SS
Sbjct: 3633 L-LVTDASSVSTGHATPLPVTDASSASTGDTTPLPVTDTSSASTGQATPLPVTSLSSVST 3691
Query: 257 GFPT------ASHSPFQPQTTAFRMLSSSCSFGEFTSAFPLQATHSGSAASVNANFAHFD 310
G T AS + T + SS S G+ PL T SA++ +A
Sbjct: 3692 GDTTPLPVTDASSASTGHATPLPVTIPSSVSTGD---TMPLPVTSPSSASTGHATPLPVT 3748
Query: 311 NFPKSSSADFG----TFNTSQSHQTASAVSKVSTNKAGLQTADKYAALANLDNIFSAGQG 366
+S+ D T +S S + A+ + T+ A + + ++ SA G
Sbjct: 3749 GLSSASTGDTTPLPVTDTSSASTRHATPLPVTDTSSASTDDTTRLP----VTDVSSASTG 3804
Query: 367 GDQGSGFGTTGKAPVGSVVSVPSQSSASSDKYAALAELDSVFSSAATSSNAYTSTSNASS 426
+T A G +P ++S A + + SSA+T ++ SS
Sbjct: 3805 HATPLPVTSTSSASTGDTTPLPVTDTSSVSTGHATSLPVTSRSSASTGHATPLPVTDTSS 3864
Query: 427 NVFGTVPVVASAQTQPASSSVPAPFGATPSTNPFVAAAGPSVASSTNPFQTNARGATAAT 486
G + T S+ P T ++ A P +ST+ T G T
Sbjct: 3865 VSTGHATPLPVTSTSSVSTGHATPLPVTSPSSASTGHATPVPVTSTSSAST---GDTTPL 3921
Query: 487 FGTASMSMPTGFGTPAPYSLPTSFS 511
T + S+ TG TP + P+S S
Sbjct: 3922 PVTNASSLSTGHATPLHVTSPSSAS 3946
Score = 40.8 bits (94), Expect = 0.003
Identities = 95/440 (21%), Positives = 152/440 (34%), Gaps = 64/440 (14%)
Query: 143 ISGSSASSTSSTPEVKPLKSLLGDSAP-----TLHLNKGTPSQSPVVGRSQGQQQEKKQF 197
+S +S + P + GD+ P T ++ G + PV RS
Sbjct: 3798 VSSASTGHATPLPVTSTSSASTGDTTPLPVTDTSSVSTGHATSLPVTSRSSA-------- 3849
Query: 198 DLLSDLGSDIFAAPAPQSTATANFANFAHFNSHAAQNSANADFANFDAFGQSSGSSNFGG 257
S A P P + ++ + H ++++ + +S SS G
Sbjct: 3850 -------STGHATPLPVTDTSS--VSTGHATPLPVTSTSSVSTGHATPLPVTSPSSASTG 3900
Query: 258 FPTASHSPFQPQTTAFRMLSSSCSFGEFTSAFPLQATHSGSAASVNANFAHFDNFPKSSS 317
H+ P T+ +SS S G+ T PL T++ S ++ +A H + +S
Sbjct: 3901 -----HATPVPVTS-----TSSASTGDTT---PLPVTNASSLSTGHATPLHVTSPSSASR 3947
Query: 318 ADFGTFNTSQSHQTASAVSKVSTNKAGLQTADKYAALANLDNIFSAGQGGDQGSGFGTTG 377
D T + + S ST +A L ++ S G T
Sbjct: 3948 GDTSTLPVTDA-------SSASTG---------HATPLPLTSLSSVSTGDTTPLPVTDTS 3991
Query: 378 KAPVGSVVSVP--SQSSASSDKYAAL-AELDSVFSSAATSSNAYTSTSNASSNVFGTVPV 434
A G +P S SS S+ L + S SS T+S T S+ S+ +PV
Sbjct: 3992 SASTGQATPLPVTSLSSVSTGDTTPLPVTIPSSASSGHTTSLPVTDASSVSTGHGTPLPV 4051
Query: 435 VASAQTQPASSSVPAPFGATPSTNPFVAAAGPSVASSTNPFQTNARGATAATFGTASMSM 494
+ T AS+ P T +++ A P + T+ T G T+ S+
Sbjct: 4052 TS---TSSASTGDTTPLPVTDTSSASTGHATPLPVTDTSSAST---GHATPLPVTSLSSV 4105
Query: 495 PTGFGTPAPYSLPTSFSGSFQQPAFPAQAAFPQQTAFSQQPNGFAAFGQTKPVVTPFGQV 554
TG TP S T S S P + P T S + +G + P T Q
Sbjct: 4106 STGHATPLAVSSAT--SASTVSSDSPLKMETPGMTTPSLKTDGGRRTATSPPPTT--SQT 4161
Query: 555 AAAGVSSNPFMTGAPTGQFP 574
+ + S T + P
Sbjct: 4162 IISTIPSTAMHTRSTAAPIP 4181
Score = 40.4 bits (93), Expect = 0.005
Identities = 83/365 (22%), Positives = 122/365 (33%), Gaps = 57/365 (15%)
Query: 268 PQTTAFRMLSSSCSFGEFTSA----FPLQATHSGSAASVNANFAHFDN-FPKSSSADFGT 322
P TT+ +LSS F + FP T + S +SV+ F F +S D
Sbjct: 346 PVTTS-TVLSSPSGFNPSGTVSQETFPSGETTTSSPSSVSNTFLVTSKVFRMPTSRDSTL 404
Query: 323 FNTSQSHQTASAVSKVSTNKAGL----QTADKYAALANLDNIFSAGQGGDQGSGFGTTGK 378
NT ++ + S T+K T + ++L S Q G TTG+
Sbjct: 405 GNTEETSLSVSGTISAITSKVSTIWWSDTLSTALSPSSLPPKISTAFHTQQSEGAETTGR 464
Query: 379 APVGSVVSV---------------PSQSSASSDKYAALAELDSVFSSAATSSNAYTSTSN 423
S S PS S+ + EL S + AAT T N
Sbjct: 465 PHERSSFSPGVSQEIFTLHETTTWPSSFSSKGHTTWSQTELPSTSTGAATR----LVTGN 520
Query: 424 ASSNVFGTVPVVASAQTQPASSSVPAPFGATPSTNPFVAAAGPSVASSTNPFQTNARGAT 483
S+ GT+P V S + P + + +T P AG + T +
Sbjct: 521 PSTGTAGTIPRVPSKVSAIGEPGEPTTYSSHSTTLPKTTGAGAQTQWTQETGTTGEALLS 580
Query: 484 AATFGTASMSMPTGFGTPAP-----------------YSLPTSFSGSFQQPAFPAQAAF- 525
+ ++ M + +P +S S S S Q+ +Q
Sbjct: 581 SPSYSVTQMIKTATSPSSSPMLDRHTSQQITTAPSTNHSTIHSTSTSPQESPAVSQRGHT 640
Query: 526 --PQQTAFSQQPNGFAAFGQTKPVVTPFGQVAAAGVSSN-------PFMTGAPT-GQFPT 575
PQ T SQ + TK V TP A+G S + P ++ A T PT
Sbjct: 641 QAPQTTQESQTTRSVSPMTDTKTVTTPGSSFTASGHSPSEIVPQDAPTISAATTFAPAPT 700
Query: 576 GSSST 580
G T
Sbjct: 701 GDGHT 705
Score = 40.0 bits (92), Expect = 0.006
Identities = 67/263 (25%), Positives = 98/263 (37%), Gaps = 34/263 (12%)
Query: 277 SSSCSFGEFTSAFPLQATHSGSAASVNANFAHFDNFPKSSSADFGTF--NTSQSHQTASA 334
+SS S G+ T PL T + SA++ A + S+ D + S T A
Sbjct: 3654 ASSASTGDTT---PLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLPVTDASSASTGHA 3710
Query: 335 VSKVSTNKAGLQTADKYAALANLDNIFSAGQG------GDQGSGFGTTGKAPVGSVVS-- 386
T + + T D + S G G + G T PV S
Sbjct: 3711 TPLPVTIPSSVSTGDTMPLPVTSPSSASTGHATPLPVTGLSSASTGDTTPLPVTDTSSAS 3770
Query: 387 --------VPSQSSASSDKYAALAELDSVFSSAATSSNA---YTSTSNASSNVFGTVPVV 435
V SSAS+D L D SSA+T TSTS+AS+ +PV
Sbjct: 3771 TRHATPLPVTDTSSASTDDTTRLPVTD--VSSASTGHATPLPVTSTSSASTGDTTPLPVT 3828
Query: 436 ASAQTQPA-SSSVPAPFGATPSTNPFVAAAGPSVASSTNPFQTNARGATAATFGTASMSM 494
++ ++S+P ++ ST A P + T+ T G T++ S+
Sbjct: 3829 DTSSVSTGHATSLPVTSRSSASTGH----ATPLPVTDTSSVST---GHATPLPVTSTSSV 3881
Query: 495 PTGFGTPAPYSLPTSFSGSFQQP 517
TG TP P + P+S S P
Sbjct: 3882 STGHATPLPVTSPSSASTGHATP 3904
Score = 39.7 bits (91), Expect = 0.008
Identities = 89/412 (21%), Positives = 148/412 (35%), Gaps = 46/412 (11%)
Query: 128 VPPEQAKVVASVHASISGSSASSTSSTPEVKPLKSLLGDSAPTLHLNK-----------G 176
+P ++ HA+ + +S++ST PL SA T H G
Sbjct: 2817 LPVTDTSSASTGHATSLPVTDTSSASTGHATPLPDTDTSSASTGHATLLPVTDTSSASIG 2876
Query: 177 TPSQSPVVGRSQGQQQEKKQFDLLSDLGSDI-FAAPAP---QSTATANFANFAHFNSHAA 232
+ PV S + S + A P P S+A+ AN H S ++
Sbjct: 2877 HATSLPVTDTSSISTGHATPLHVTSPSSASTGHATPLPVTDTSSASTGHANPLHVTSPSS 2936
Query: 233 QNSANAD-FANFDAFGQSSGSSNFGGFPTASHSPFQP-QTTAFRMLSSSCSFGEFTSAFP 290
++ +A D S+G + P S S TT + S S + T+ P
Sbjct: 2937 ASTGHATPLPVTDTSSASTGHAT--PLPVTSLSSVSTGDTTPLPVTSPSSASTGHTTPLP 2994
Query: 291 LQATHSGSAASVNANFAHFDNFPKSSSADFGTFNTS-------QSHQTASAVSKVSTNKA 343
+ T S S A P +S++ T +T+ S T A T+ +
Sbjct: 2995 VTDTSSASTGQATA-------LPVTSTSSASTGDTTPLPVTDTSSASTGQATPLPVTSLS 3047
Query: 344 GLQTADKYAALANLDNIFSAGQGGD---QGSGFGTTGKAPVGSVVSVPSQSSASSDKYAA 400
+ T D + S G + +TG+A V S+ S S+ +
Sbjct: 3048 SVSTGDTTPLPVTSPSSASTGHATPLLVTDASSASTGQATPLPVTSLSSVSTGDTTPLPV 3107
Query: 401 LAELDSVFSSAATSSNAYTSTSNASSNVFGTVPVVASAQTQPA-SSSVPAPFGATPSTNP 459
+ S S+ +S T TS+AS+ ++PV ++ ++S+P ++ ST
Sbjct: 3108 TSP--SSASTGHATSLPVTDTSSASTGDTTSLPVTDTSSAYTGDTTSLPVTDTSSSSTGD 3165
Query: 460 FVAAAGPSVASSTNPFQTNARGATAATFGTASMSMPTGFGTPAPYSLPTSFS 511
P + + T+ T G T + S TG TP + P+S S
Sbjct: 3166 TT----PLLVTETSSVST---GHATPLLVTDASSASTGHATPLHVTSPSSAS 3210
Score = 38.5 bits (88), Expect = 0.017
Identities = 92/432 (21%), Positives = 144/432 (33%), Gaps = 60/432 (13%)
Query: 142 SISGSSASSTSSTPEVKPLKSLLGDSAP-----TLHLNKGTPSQSPVVGRSQGQQQEKKQ 196
S+S +S T P P + GD+ P ++ G + PV S
Sbjct: 1525 SLSSASTGDTMPLPVTSPSSASTGDTTPLPVTDASSVSTGHTTPLPVTSPSSASTGHTTP 1584
Query: 197 FDLLSDLGSDIFAAPAPQSTATANFANFAHFNSHAAQNSANADFANFDAFGQSSGSSNFG 256
+ +D S P + + A+ H ++++A + ++ SS
Sbjct: 1585 LPV-TDTSSASKGDTTPLPVTSPSSASTGHTTPLPVTDTSSASTGDTTPLPVTNASSLST 1643
Query: 257 GFPTASH--SPFQPQTTAFRML----SSSCSFGEFTSAFPLQATHSGSAAS--------- 301
G T H SP T L +SS S G T PL T SA +
Sbjct: 1644 GHATPLHVTSPSSASTGHATPLPVTSTSSASTGHAT---PLPVTGLSSATTDDTTRLPVT 1700
Query: 302 --VNANFAHFDNFPKSSSADFGTFNT-----------SQSHQTASAVSKVSTNKAGLQT- 347
+A+ P +S + T +T S H + V+ S+ G T
Sbjct: 1701 DVSSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHASPLLVTDASSASTGQATP 1760
Query: 348 ---------ADKYAALANLDNIFSAGQGGDQGSGFGTTGKAPVGSVVSVP--SQSSASSD 396
+ +A + + SA A G + +P S SSAS+
Sbjct: 1761 LPVTDTSSVSTAHATPLPVTGLSSASTDDTTRLPVTDVSSASTGQAIPLPVTSPSSASTG 1820
Query: 397 KYAALAELD-SVFSSAATSSNAYTSTSNASSNVFGTVPVVASAQTQP----------ASS 445
L D S S+ T+S T S+ASS ++PV ++ ASS
Sbjct: 1821 DTTPLPVTDASSASTGDTTSLPVTIPSSASSGHTTSLPVTDASSVSTGHATSLLVTDASS 1880
Query: 446 SVPAPFGATPSTNPFVAAAGPSVASSTNPFQTNARGATAATFGTASMSMPTGFGTPAPYS 505
P T+ A+ G + + + G + T+ S TG TP P +
Sbjct: 1881 VSTGDTTPLPVTDTNSASTGDTTPLHVTDASSVSTGHATSLPVTSLSSASTGDTTPLPVT 1940
Query: 506 LPTSFSGSFQQP 517
P+S S P
Sbjct: 1941 SPSSASSGHTTP 1952
Score = 37.0 bits (84), Expect = 0.050
Identities = 57/250 (22%), Positives = 97/250 (38%), Gaps = 26/250 (10%)
Query: 278 SSCSFGEFTSAFPLQATHSGSAASVNANFAHFDNFPKSSSADFGTFNTS-------QSHQ 330
SS S G+ T PL T + SA++ H + P + ++ T +T+ S
Sbjct: 1079 SSASTGDTT---PLPVTDTSSAST-----GHATSLPVTDTSSVSTGHTTPLPVTDTSSAS 1130
Query: 331 TASAVSKVSTNKAGLQTADKYAALANLDNIFSAGQGGDQGSGFGTTGKAPVGSVVSVPSQ 390
T A S T+ + + T + ++ + SA G + G +P
Sbjct: 1131 TGHATSLPVTDTSSVSTG--HTTPLHVTDASSASTGQATPLPVTSLSSVSTGDTTPLPVT 1188
Query: 391 SSASSDKYAALAELDSVFSSAATSSNA---YTSTSNASSNVFGTVPVVASAQTQPASSSV 447
S +S+ A L + SSA+T T S+ S++ ++PV + AS+
Sbjct: 1189 SPSSASTGHATPLLVTDTSSASTGHATPLPVTDASSVSTDHATSLPVTIPSA---ASTGH 1245
Query: 448 PAPFGATPSTNPFVAAAGPSVASSTNPFQTNARGATAATFGTASMSMPTGFGTPAPYSLP 507
P T +++ A + + T+ T G T T++ S TG TP + P
Sbjct: 1246 TTPLPVTDTSSASTGQATSLLVTDTSSVST---GDTTPLPVTSTSSASTGHVTPLHVTSP 1302
Query: 508 TSFSGSFQQP 517
+S S P
Sbjct: 1303 SSASTGHATP 1312
Score = 32.3 bits (72), Expect = 1.2
Identities = 79/334 (23%), Positives = 116/334 (34%), Gaps = 56/334 (16%)
Query: 144 SGSSASSTSSTP-EVKPLKSLLGDSAPTLHL------NKGTPSQSPVVGRSQGQQQEKKQ 196
S SSAS+ +TP V SL A LH+ ++G S PV S
Sbjct: 3909 STSSASTGDTTPLPVTNASSLSTGHATPLHVTSPSSASRGDTSTLPVTDASSASTGHATP 3968
Query: 197 FDL--LSDLGSDIFAAPAPQSTATANFANFAHFNSHAAQNSANADFANFDAFGQSSGSSN 254
L LS + + T++A+ + + + D SS SS
Sbjct: 3969 LPLTSLSSVSTGDTTPLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLPVTIPSSASSG 4028
Query: 255 FGGFPTASHSPFQPQTTAFRMLSSSCSFGEFTSAFPLQATHSGSAASVNANFAHFDNFPK 314
H+ P T A SS S G T PL T + SA++ D P
Sbjct: 4029 --------HTTSLPVTDA-----SSVSTGHGT---PLPVTSTSSASTG-------DTTPL 4065
Query: 315 SSSADFGTFNTSQSHQTASAVSKVSTNKAGLQTADKYAALANLDNIFSAGQGGDQGSGFG 374
+ T + S H T V+ S+ G T +L+++
Sbjct: 4066 PVT---DTSSASTGHATPLPVTDTSSASTGHATPLPVTSLSSV----------------- 4105
Query: 375 TTGKAPVGSVVSVPSQSSASSDKYAALAELDSVFSSAATSSNAYTSTS---NASSNVFGT 431
+TG A +V S S S+ SSD + S T T+TS S + T
Sbjct: 4106 STGHATPLAVSSATSASTVSSDSPLKMETPGMTTPSLKTDGGRRTATSPPPTTSQTIIST 4165
Query: 432 VPVVASAQTQPASSSVPAPFGATPSTNPFVAAAG 465
+P A T+ ++ +P S P+ A AG
Sbjct: 4166 IPSTA-MHTRSTAAPIPILPERGVSLFPYGAGAG 4198
Score = 31.6 bits (70), Expect = 2.1
Identities = 30/157 (19%), Positives = 58/157 (36%)
Query: 330 QTASAVSKVSTNKAGLQTADKYAALANLDNIFSAGQGGDQGSGFGTTGKAPVGSVVSVPS 389
+TA+ V+ + A L+ A+ + SA Q TT KA ++ + +
Sbjct: 39 KTAAPVTSTGSTTATLEGQSTAASSRTSNQDISASSQNHQTKSTETTSKAQTDTLTQMMT 98
Query: 390 QSSASSDKYAALAELDSVFSSAATSSNAYTSTSNASSNVFGTVPVVASAQTQPASSSVPA 449
+ SS + E + ++ T+T +S S +S
Sbjct: 99 STLFSSPSVHNVMETAPPDEMTTSFPSSVTNTLMMTSKTITMTTSTDSTLGNTEETSTAG 158
Query: 450 PFGATPSTNPFVAAAGPSVASSTNPFQTNARGATAAT 486
+TP T+ AG S T ++T+ + +A++
Sbjct: 159 TESSTPVTSAVSITAGQEGQSRTTSWRTSIQDTSASS 195
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.123 0.354
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,783,966
Number of Sequences: 37866
Number of extensions: 1081147
Number of successful extensions: 5590
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 85
Number of HSP's successfully gapped in prelim test: 322
Number of HSP's that attempted gapping in prelim test: 4178
Number of HSP's gapped (non-prelim): 1161
length of query: 584
length of database: 18,247,518
effective HSP length: 108
effective length of query: 476
effective length of database: 14,157,990
effective search space: 6739203240
effective search space used: 6739203240
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.