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Search of human proteins with 205830470
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|205830470 sialic acid binding Ig-like lectin 11 isoform 1
[Homo sapiens]
(698 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|205830470 sialic acid binding Ig-like lectin 11 isoform 1 [Ho... 1434 0.0
gi|31377639 sialic acid binding Ig-like lectin 10 [Homo sapiens] 954 0.0
gi|205830473 sialic acid binding Ig-like lectin 11 isoform 2 [Ho... 930 0.0
gi|4502659 sialic acid binding Ig-like lectin 5 [Homo sapiens] 327 3e-89
gi|148762980 sialic acid binding Ig-like lectin 14 [Homo sapiens] 273 3e-73
gi|94538343 sialic acid binding Ig-like lectin 8 [Homo sapiens] 271 1e-72
gi|7657570 sialic acid binding Ig-like lectin 7 isoform 1 [Homo ... 264 2e-70
gi|23943856 sialic acid binding Ig-like lectin 9 [Homo sapiens] 250 4e-66
gi|193794821 sialic acid binding Ig-like lectin 6 isoform 1 prec... 248 1e-65
gi|193794817 sialic acid binding Ig-like lectin 6 isoform 3 prec... 244 2e-64
gi|16506826 sialic acid binding immunoglobulin-like lectin-like ... 239 8e-63
gi|16506828 sialic acid binding immunoglobulin-like lectin-like ... 239 8e-63
gi|193794819 sialic acid binding Ig-like lectin 6 isoform 2 prec... 225 9e-59
gi|130979981 CD33 antigen isoform 1 precursor [Homo sapiens] 214 2e-55
gi|11225258 myelin associated glycoprotein isoform a precursor [... 171 3e-42
gi|18104957 myelin associated glycoprotein isoform b precursor [... 171 3e-42
gi|118197279 sialic acid binding Ig-like lectin 7 isoform 2 [Hom... 132 1e-30
gi|13489095 sialoadhesin precursor [Homo sapiens] 108 2e-23
gi|130980072 CD33 antigen isoform 2 precursor [Homo sapiens] 96 9e-20
gi|157168355 CD22 molecule [Homo sapiens] 95 3e-19
gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens] 92 1e-18
gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens] 92 1e-18
gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens] 92 1e-18
gi|118572606 hemicentin 1 [Homo sapiens] 87 5e-17
gi|27735027 hypothetical protein LOC284369 [Homo sapiens] 84 4e-16
gi|239755187 PREDICTED: similar to hemicentin 2 [Homo sapiens] 83 1e-15
gi|94420689 neural cell adhesion molecule 1 isoform 1 [Homo sapi... 83 1e-15
gi|115529478 neural cell adhesion molecule 1 isoform 3 [Homo sap... 83 1e-15
gi|109150416 peroxidasin [Homo sapiens] 83 1e-15
gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens] 80 5e-15
>gi|205830470 sialic acid binding Ig-like lectin 11 isoform 1 [Homo
sapiens]
Length = 698
Score = 1434 bits (3711), Expect = 0.0
Identities = 698/698 (100%), Positives = 698/698 (100%)
Query: 1 MVPGQAQPQSPEMLLLPLLLPVLGAGSLNKDPSYSLQVQRQVPVPEGLCVIVSCNLSYPR 60
MVPGQAQPQSPEMLLLPLLLPVLGAGSLNKDPSYSLQVQRQVPVPEGLCVIVSCNLSYPR
Sbjct: 1 MVPGQAQPQSPEMLLLPLLLPVLGAGSLNKDPSYSLQVQRQVPVPEGLCVIVSCNLSYPR 60
Query: 61 DGWDESTAAYGYWFKGRTSPKTGAPVATNNQSREVEMSTRDRFQLTGDPGKGSCSLVIRD 120
DGWDESTAAYGYWFKGRTSPKTGAPVATNNQSREVEMSTRDRFQLTGDPGKGSCSLVIRD
Sbjct: 61 DGWDESTAAYGYWFKGRTSPKTGAPVATNNQSREVEMSTRDRFQLTGDPGKGSCSLVIRD 120
Query: 121 AQREDEAWYFFRVERGSRVRHSFLSNAFFLKVTALTKKPDVYIPETLEPGQPVTVICVFN 180
AQREDEAWYFFRVERGSRVRHSFLSNAFFLKVTALTKKPDVYIPETLEPGQPVTVICVFN
Sbjct: 121 AQREDEAWYFFRVERGSRVRHSFLSNAFFLKVTALTKKPDVYIPETLEPGQPVTVICVFN 180
Query: 181 WAFKKCPAPSFSWTGAALSPRRTRPSTSHFSVLSFTPSPQDHDTDLTCHVDFSRKGVSAQ 240
WAFKKCPAPSFSWTGAALSPRRTRPSTSHFSVLSFTPSPQDHDTDLTCHVDFSRKGVSAQ
Sbjct: 181 WAFKKCPAPSFSWTGAALSPRRTRPSTSHFSVLSFTPSPQDHDTDLTCHVDFSRKGVSAQ 240
Query: 241 RTVRLRVAYAPKDLIISISHDNTSALELQGNVIYLEVQKGQFLRLLCAADSQPPATLSWV 300
RTVRLRVAYAPKDLIISISHDNTSALELQGNVIYLEVQKGQFLRLLCAADSQPPATLSWV
Sbjct: 241 RTVRLRVAYAPKDLIISISHDNTSALELQGNVIYLEVQKGQFLRLLCAADSQPPATLSWV 300
Query: 301 LQDRVLSSSHPWGPRTLGLELRGVRAGDSGRYTCRAENRLGSQQQALDLSVQYPPENLRV 360
LQDRVLSSSHPWGPRTLGLELRGVRAGDSGRYTCRAENRLGSQQQALDLSVQYPPENLRV
Sbjct: 301 LQDRVLSSSHPWGPRTLGLELRGVRAGDSGRYTCRAENRLGSQQQALDLSVQYPPENLRV 360
Query: 361 MVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPPARLSWTRWGQTVGPSQPSDPGV 420
MVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPPARLSWTRWGQTVGPSQPSDPGV
Sbjct: 361 MVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPPARLSWTRWGQTVGPSQPSDPGV 420
Query: 421 LELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSVHYPPQLLGPSCSWEAEGLHCSCSSQAS 480
LELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSVHYPPQLLGPSCSWEAEGLHCSCSSQAS
Sbjct: 421 LELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSVHYPPQLLGPSCSWEAEGLHCSCSSQAS 480
Query: 481 PAPSLRWWLGEELLEGNSSQGSFEVTPSSAGPWANSSLSLHGGLSSGLRLRCKAWNVHGA 540
PAPSLRWWLGEELLEGNSSQGSFEVTPSSAGPWANSSLSLHGGLSSGLRLRCKAWNVHGA
Sbjct: 481 PAPSLRWWLGEELLEGNSSQGSFEVTPSSAGPWANSSLSLHGGLSSGLRLRCKAWNVHGA 540
Query: 541 QSGSVFQLLPGKLEHGGGLGLGAALGAGVAALLAFCSCLVVFRVKICRKEARKRAAAEQD 600
QSGSVFQLLPGKLEHGGGLGLGAALGAGVAALLAFCSCLVVFRVKICRKEARKRAAAEQD
Sbjct: 541 QSGSVFQLLPGKLEHGGGLGLGAALGAGVAALLAFCSCLVVFRVKICRKEARKRAAAEQD 600
Query: 601 VPSTLGPISQGHQHECSAGSSQDHPPPGAATYTPGKGEEQELHYASLSFQGLRLWEPADQ 660
VPSTLGPISQGHQHECSAGSSQDHPPPGAATYTPGKGEEQELHYASLSFQGLRLWEPADQ
Sbjct: 601 VPSTLGPISQGHQHECSAGSSQDHPPPGAATYTPGKGEEQELHYASLSFQGLRLWEPADQ 660
Query: 661 EAPSTTEYSEIKIHTGQPLRGPGFGLQLEREMSGMVPK 698
EAPSTTEYSEIKIHTGQPLRGPGFGLQLEREMSGMVPK
Sbjct: 661 EAPSTTEYSEIKIHTGQPLRGPGFGLQLEREMSGMVPK 698
>gi|31377639 sialic acid binding Ig-like lectin 10 [Homo sapiens]
Length = 697
Score = 954 bits (2466), Expect = 0.0
Identities = 489/695 (70%), Positives = 545/695 (78%), Gaps = 36/695 (5%)
Query: 14 LLLPLLLPVLGAGSLNKDPSYSLQVQRQVPVPEGLCVIVSCNLSYPRDGWDESTAAYGYW 73
+LLPLLL L GS D + ++VQ V VPEGLC+ V C+ SYPR W ST AYGYW
Sbjct: 1 MLLPLLLSSLLGGSQAMDGRFWIRVQESVMVPEGLCISVPCSFSYPRQDWTGSTPAYGYW 60
Query: 74 FKGRTSPKTGAPVATNNQSREVEMSTRDRFQLTGDPGKGSCSLVIRDAQREDEAWYFFRV 133
FK T GAPVATN+QSREVEMSTR RFQLTGDP KG+CSLVIRDAQ +DE+ YFFRV
Sbjct: 61 FKAVTETTKGAPVATNHQSREVEMSTRGRFQLTGDPAKGNCSLVIRDAQMQDESQYFFRV 120
Query: 134 ERGSRVRHSFLSNAFFLKVTALTKKPDVYIPETLEPGQPVTVICVFNWAFKKCPAPSFSW 193
ERGS VR++F+++ FFLKVTALT+KPDVYIPETLEPGQPVTVICVFNWAF++CP PSFSW
Sbjct: 121 ERGSYVRYNFMNDGFFLKVTALTQKPDVYIPETLEPGQPVTVICVFNWAFEECPPPSFSW 180
Query: 194 TGAALSPRRTRPSTSHFSVLSFTPSPQDHDTDLTCHVDFSRKGVSAQRTVRLRVAYAPKD 253
TGAALS + T+P+TSHFSVLSFTP PQDH+TDLTCHVDFSRKGVSAQRTVRLRVAYAP+D
Sbjct: 181 TGAALSSQGTKPTTSHFSVLSFTPRPQDHNTDLTCHVDFSRKGVSAQRTVRLRVAYAPRD 240
Query: 254 LIISISHDNTSALELQ--GNVIYLEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHP 311
L+ISIS DNT ALE Q GNV YLE QKGQFLRLLCAADSQPPATLSWVLQ+RVLSSSHP
Sbjct: 241 LVISISRDNTPALEPQPQGNVPYLEAQKGQFLRLLCAADSQPPATLSWVLQNRVLSSSHP 300
Query: 312 WGPRTLGLELRGVRAGDSGRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLE 371
WGPR LGLEL GV+AGDSGRYTCRAENRLGSQQ+ALDLSVQYPPENLRVMVSQANRTVLE
Sbjct: 301 WGPRPLGLELPGVKAGDSGRYTCRAENRLGSQQRALDLSVQYPPENLRVMVSQANRTVLE 360
Query: 372 NLGNGTSLPVLEGQSLRLVCVTHSSPPARLSWTRWGQTVGPSQPSDPGVLELPPIQMEHE 431
NLGNGTSLPVLEGQSL LVCVTHSSPPARLSWT+ GQ + PSQPSDPGVLELP +Q+EHE
Sbjct: 361 NLGNGTSLPVLEGQSLCLVCVTHSSPPARLSWTQRGQVLSPSQPSDPGVLELPRVQVEHE 420
Query: 432 GEFTCHAQHPLGSQHVSLSLSVHYPPQLLGPSCSWEAEGLHCSCSSQASPAPSLRWWLGE 491
GEFTCHA+HPLGSQHVSLSLSVHY P+LLGPSCSWEAEGLHCSCSSQASPAPSLRWWLGE
Sbjct: 421 GEFTCHARHPLGSQHVSLSLSVHYSPKLLGPSCSWEAEGLHCSCSSQASPAPSLRWWLGE 480
Query: 492 ELLEGNSSQGSFEVTPSSAGPWANSSLSLHGGLSSGLRLRCKAWNVHGAQSGSVFQLLPG 551
ELLEGNSSQ SFEVTPSSAGPWANSSLSLHGGLSSGLRLRC+AWNVHGAQSGS+ QL
Sbjct: 481 ELLEGNSSQDSFEVTPSSAGPWANSSLSLHGGLSSGLRLRCEAWNVHGAQSGSILQLPDK 540
Query: 552 KLEHGGGLGLGAALGAGVAALLAFCSCLVVFRVKICRK----EARKRAAAEQ------DV 601
K GA LG G+ ALL C L++ ++ R+ R R + +V
Sbjct: 541 KGLISTAFSNGAFLGIGITALLFLCLALIIMKILPKRRTQTETPRPRFSRHSTILDYINV 600
Query: 602 PSTLGPISQGHQHECSAGSSQDHPPPGA-----------------------ATYTPGKGE 638
T GP++Q + + S + PPGA +T P E
Sbjct: 601 VPTAGPLAQKRNQKATPNSPRTPLPPGAPSPESKKNQKKQYQLPSFPEPKSSTQAPESQE 660
Query: 639 EQ-ELHYASLSFQGLRLWEPADQEAPSTTEYSEIK 672
Q ELHYA+L+F G+R A + +Y+E+K
Sbjct: 661 SQEELHYATLNFPGVRPRPEARMPKGTQADYAEVK 695
>gi|205830473 sialic acid binding Ig-like lectin 11 isoform 2 [Homo
sapiens]
Length = 602
Score = 930 bits (2404), Expect = 0.0
Identities = 454/455 (99%), Positives = 455/455 (100%)
Query: 1 MVPGQAQPQSPEMLLLPLLLPVLGAGSLNKDPSYSLQVQRQVPVPEGLCVIVSCNLSYPR 60
MVPGQAQPQSPEMLLLPLLLPVLGAGSLNKDPSYSLQVQRQVPVPEGLCVIVSCNLSYPR
Sbjct: 1 MVPGQAQPQSPEMLLLPLLLPVLGAGSLNKDPSYSLQVQRQVPVPEGLCVIVSCNLSYPR 60
Query: 61 DGWDESTAAYGYWFKGRTSPKTGAPVATNNQSREVEMSTRDRFQLTGDPGKGSCSLVIRD 120
DGWDESTAAYGYWFKGRTSPKTGAPVATNNQSREVEMSTRDRFQLTGDPGKGSCSLVIRD
Sbjct: 61 DGWDESTAAYGYWFKGRTSPKTGAPVATNNQSREVEMSTRDRFQLTGDPGKGSCSLVIRD 120
Query: 121 AQREDEAWYFFRVERGSRVRHSFLSNAFFLKVTALTKKPDVYIPETLEPGQPVTVICVFN 180
AQREDEAWYFFRVERGSRVRHSFLSNAFFLKVTALTKKPDVYIPETLEPGQPVTVICVFN
Sbjct: 121 AQREDEAWYFFRVERGSRVRHSFLSNAFFLKVTALTKKPDVYIPETLEPGQPVTVICVFN 180
Query: 181 WAFKKCPAPSFSWTGAALSPRRTRPSTSHFSVLSFTPSPQDHDTDLTCHVDFSRKGVSAQ 240
WAFKKCPAPSFSWTGAALSPRRTRPSTSHFSVLSFTPSPQDHDTDLTCHVDFSRKGVSAQ
Sbjct: 181 WAFKKCPAPSFSWTGAALSPRRTRPSTSHFSVLSFTPSPQDHDTDLTCHVDFSRKGVSAQ 240
Query: 241 RTVRLRVAYAPKDLIISISHDNTSALELQGNVIYLEVQKGQFLRLLCAADSQPPATLSWV 300
RTVRLRVAYAPKDLIISISHDNTSALELQGNVIYLEVQKGQFLRLLCAADSQPPATLSWV
Sbjct: 241 RTVRLRVAYAPKDLIISISHDNTSALELQGNVIYLEVQKGQFLRLLCAADSQPPATLSWV 300
Query: 301 LQDRVLSSSHPWGPRTLGLELRGVRAGDSGRYTCRAENRLGSQQQALDLSVQYPPENLRV 360
LQDRVLSSSHPWGPRTLGLELRGVRAGDSGRYTCRAENRLGSQQQALDLSVQYPPENLRV
Sbjct: 301 LQDRVLSSSHPWGPRTLGLELRGVRAGDSGRYTCRAENRLGSQQQALDLSVQYPPENLRV 360
Query: 361 MVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPPARLSWTRWGQTVGPSQPSDPGV 420
MVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPPARLSWTRWGQTVGPSQPSDPGV
Sbjct: 361 MVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPPARLSWTRWGQTVGPSQPSDPGV 420
Query: 421 LELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSVHY 455
LELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSVH+
Sbjct: 421 LELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSVHW 455
Score = 382 bits (982), Expect = e-106
Identities = 220/390 (56%), Positives = 251/390 (64%), Gaps = 38/390 (9%)
Query: 333 TCRAE-NRLG-SQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLV 390
TC + +R G S Q+ + L V Y P++L + +S N + LE GN L V +GQ LRL+
Sbjct: 227 TCHVDFSRKGVSAQRTVRLRVAYAPKDLIISISHDNTSALELQGNVIYLEVQKGQFLRLL 286
Query: 391 CVTHSSPPARLSWTRWGQTVGPSQPSDPGVL--ELPPIQMEHEGEFTCHAQHPLGSQHVS 448
C S PPA LSW + + S P P L EL ++ G +TC A++ LGSQ +
Sbjct: 287 CAADSQPPATLSWVLQDRVLSSSHPWGPRTLGLELRGVRAGDSGRYTCRAENRLGSQQQA 346
Query: 449 LSLSVHYPPQLLGPSCSW------------------EAEGLHCSCSSQASPAPSLRWWLG 490
L LSV YPP+ L S E + L C + +SP L W
Sbjct: 347 LDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPPARLSWTRW 406
Query: 491 EELLEGN--SSQGSFEVTPSSAGPWANSSLSLHGGLSSGLRLRCKAWNVHGAQSGSVFQL 548
+ + + S G E+ P H G C A + G+Q S+
Sbjct: 407 GQTVGPSQPSDPGVLELPPIQME---------HEG-----EFTCHAQHPLGSQHVSLSLS 452
Query: 549 LPGKLEHGGGLGLGAALGAGVAALLAFCSCLVVFRVKICRKEARKRAAAEQDVPSTLGPI 608
+ KLEHGGGLGLGAALGAGVAALLAFCSCLVVFRVKICRKEARKRAAAEQDVPSTLGPI
Sbjct: 453 VHWKLEHGGGLGLGAALGAGVAALLAFCSCLVVFRVKICRKEARKRAAAEQDVPSTLGPI 512
Query: 609 SQGHQHECSAGSSQDHPPPGAATYTPGKGEEQELHYASLSFQGLRLWEPADQEAPSTTEY 668
SQGHQHECSAGSSQDHPPPGAATYTPGKGEEQELHYASLSFQGLRLWEPADQEAPSTTEY
Sbjct: 513 SQGHQHECSAGSSQDHPPPGAATYTPGKGEEQELHYASLSFQGLRLWEPADQEAPSTTEY 572
Query: 669 SEIKIHTGQPLRGPGFGLQLEREMSGMVPK 698
SEIKIHTGQPLRGPGFGLQLEREMSGMVPK
Sbjct: 573 SEIKIHTGQPLRGPGFGLQLEREMSGMVPK 602
Score = 82.4 bits (202), Expect = 1e-15
Identities = 51/131 (38%), Positives = 72/131 (54%), Gaps = 4/131 (3%)
Query: 227 TCHVDFSRKGVSAQRTVRLRVAYAPKDLIISISHDNTSALELQGNVIYLEVQKGQFLRLL 286
TC + +R G S Q+ + L V Y P++L + +S N + LE GN L V +GQ LRL+
Sbjct: 333 TCRAE-NRLG-SQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLV 390
Query: 287 CAADSQPPATLSWVLQDRVLSSSHPWGPRTLGLELRGVRAGDSGRYTCRAENRLGSQQQA 346
C S PPA LSW + + S P P L EL ++ G +TC A++ LGSQ +
Sbjct: 391 CVTHSSPPARLSWTRWGQTVGPSQPSDPGVL--ELPPIQMEHEGEFTCHAQHPLGSQHVS 448
Query: 347 LDLSVQYPPEN 357
L LSV + E+
Sbjct: 449 LSLSVHWKLEH 459
>gi|4502659 sialic acid binding Ig-like lectin 5 [Homo sapiens]
Length = 551
Score = 327 bits (837), Expect = 3e-89
Identities = 200/419 (47%), Positives = 256/419 (61%), Gaps = 20/419 (4%)
Query: 264 SALELQGNVIYLE-VQKGQFLRLLCA----ADSQPPATLSWVLQDRVLSSSHPWGPRTLG 318
+AL + ++ +LE ++ G+ RL C+ ++ PP T SW LS P R+
Sbjct: 140 TALIEKPDIHFLEPLESGRPTRLSCSLPGSCEAGPPLTFSWT--GNALSPLDPETTRSSE 197
Query: 319 LELRGVRAGDSGRYTCRAENRLGSQ---QQALDLSVQYPPENLRVMVSQANRTVLENLGN 375
L L TC+ + R G+Q ++ + L+V Y P+ + + N LE L N
Sbjct: 198 LTLTPRPEDHGTNLTCQMK-RQGAQVTTERTVQLNVSYAPQTITIF---RNGIALEILQN 253
Query: 376 GTSLPVLEGQSLRLVCVTHSSPPARLSWTRWGQTVGPSQPSDPGVLELPPIQMEHEGEFT 435
+ LPVLEGQ+LRL+C S+PPA LSW + + + S+ G+LEL ++ EG FT
Sbjct: 254 TSYLPVLEGQALRLLCDAPSNPPAHLSWFQGSPALNATPISNTGILELRRVRSAEEGGFT 313
Query: 436 CHAQHPLGSQHVSLSLSVHYPPQLLGPSCSWEAEGLHCSCSSQASPAPSLRWWLGEELLE 495
C AQHPLG + L+LSV+ PQLLGPSCSWEAEGLHC CS +A PAPSL W L E+ LE
Sbjct: 314 CRAQHPLGFLQIFLNLSVYSLPQLLGPSCSWEAEGLHCRCSFRARPAPSLCWRLEEKPLE 373
Query: 496 GNSSQGSFEVTPSSAGPWANSSLSLHGGLSSGLRLRCKAWNVHGAQSGSVFQLLPGKLEH 555
GNSSQGSF+V SSAGPWANSSL LHGGLSS L++ CKAWN++G+QSGSV LL G+
Sbjct: 374 GNSSQGSFKVNSSSAGPWANSSLILHGGLSSDLKVSCKAWNIYGSQSGSVL-LLQGRSNL 432
Query: 556 GGGLGLGAALGAGVAALLAFCSCLVVFR-VKICRKEARKRAAAEQDVPSTLGPISQGHQH 614
G G+ A GAGV ALL C CL+ F VK RK+A R D +G I+ G +
Sbjct: 433 GTGVVPAALGGAGVMALLCICLCLIFFLIVKARRKQAAGRPEKMDDEDPIMGTITSGSRK 492
Query: 615 ECSAGSSQDH-PPPGAATYTPGKGEEQELHYASLSFQGLRLWEPADQEAPSTTEYSEIK 672
+ S D PPG A P E++ELHYASLSF ++ EP DQEAPSTTEYSEIK
Sbjct: 493 KPWPDSPGDQASPPGDA---PPLEEQKELHYASLSFSEMKSREPKDQEAPSTTEYSEIK 548
Score = 271 bits (693), Expect = 1e-72
Identities = 160/345 (46%), Positives = 207/345 (60%), Gaps = 8/345 (2%)
Query: 15 LLPLLL-PVLGAGSLNKDPSYSLQVQRQVPVPEGLCVIVSCNLSYPRDGWDESTAAYGYW 73
+LPLLL P+L GSL + P Y LQVQ+ V V EGLCV+V C+ SYP W S Y YW
Sbjct: 1 MLPLLLLPLLWGGSLQEKPVYELQVQKSVTVQEGLCVLVPCSFSYPWRSWYSSPPLYVYW 60
Query: 74 FKGRTSPKTGAPVATNNQSREVEMSTRDRFQLTGDPGKGSCSLVIRDAQREDEAWYFFRV 133
F+ P VATNN R V+ T+ RF+L GD K +CSL I DA+ ED YFFRV
Sbjct: 61 FRDGEIPYYAEVVATNNPDRRVKPETQGRFRLLGDVQKKNCSLSIGDARMEDTGSYFFRV 120
Query: 134 ERGSRVRHSFLSNAFFLKVTALTKKPDVYIPETLEPGQPVTVICVFNWAFKKCPAPSFSW 193
ERG V++S+ N L+VTAL +KPD++ E LE G+P + C + + P +FSW
Sbjct: 121 ERGRDVKYSYQQNKLNLEVTALIEKPDIHFLEPLESGRPTRLSCSLPGSCEAGPPLTFSW 180
Query: 194 TGAALSPRRTRPSTSHFSVLSFTPSPQDHDTDLTCHVDFSRKGVSAQRTVRLRVAYAPKD 253
TG ALSP P T+ S L+ TP P+DH T+LTC + V+ +RTV+L V+YAP+
Sbjct: 181 TGNALSP--LDPETTRSSELTLTPRPEDHGTNLTCQMKRQGAQVTTERTVQLNVSYAPQT 238
Query: 254 LIISISHDNTSALELQGNVIYLEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWG 313
+ I N ALE+ N YL V +GQ LRLLC A S PPA LSW L+++
Sbjct: 239 ITI---FRNGIALEILQNTSYLPVLEGQALRLLCDAPSNPPAHLSWFQGSPALNATPI-- 293
Query: 314 PRTLGLELRGVRAGDSGRYTCRAENRLGSQQQALDLSVQYPPENL 358
T LELR VR+ + G +TCRA++ LG Q L+LSV P+ L
Sbjct: 294 SNTGILELRRVRSAEEGGFTCRAQHPLGFLQIFLNLSVYSLPQLL 338
>gi|148762980 sialic acid binding Ig-like lectin 14 [Homo sapiens]
Length = 396
Score = 273 bits (699), Expect = 3e-73
Identities = 156/341 (45%), Positives = 206/341 (60%), Gaps = 7/341 (2%)
Query: 15 LLPLLL-PVLGAGSLNKDPSYSLQVQRQVPVPEGLCVIVSCNLSYPRDGWDESTAAYGYW 73
+LPLLL P+L GSL + P Y LQVQ+ V V EGLCV+V C+ SYP W S Y YW
Sbjct: 1 MLPLLLLPLLWGGSLQEKPVYELQVQKSVTVQEGLCVLVPCSFSYPWRSWYSSPPLYVYW 60
Query: 74 FKGRTSPKTGAPVATNNQSREVEMSTRDRFQLTGDPGKGSCSLVIRDAQREDEAWYFFRV 133
F+ P VATNN R V+ T+ RF+L GD K +CSL I DA+ ED YFFRV
Sbjct: 61 FRDGEIPYYAEVVATNNPDRRVKPETQGRFRLLGDVQKKNCSLSIGDARMEDTGSYFFRV 120
Query: 134 ERGSRVRHSFLSNAFFLKVTALTKKPDVYIPETLEPGQPVTVICVFNWAFKKCPAPSFSW 193
ERG V++S+ N L+VTAL +KPD++ E LE G+P + C + + P +FSW
Sbjct: 121 ERGRDVKYSYQQNKLNLEVTALIEKPDIHFLEPLESGRPTRLSCSLPGSCEAGPPLTFSW 180
Query: 194 TGAALSPRRTRPSTSHFSVLSFTPSPQDHDTDLTCHVDFSRKGVSAQRTVRLRVAYAPKD 253
TG ALSP P T+ S L+ TP P+DH T+LTC V V+ +RTV+L V+YAP++
Sbjct: 181 TGNALSP--LDPETTRSSELTLTPRPEDHGTNLTCQVKRQGAQVTTERTVQLNVSYAPQN 238
Query: 254 LIISISHDN--TSALELQGNVIYLEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHP 311
L ISI N +AL + N + + +Q+GQ L L C DS PPA+LSW + + L+ S
Sbjct: 239 LAISIFFRNGTGTALRILSNGMSVPIQEGQSLFLACTVDSNPPASLSWFREGKALNPSQT 298
Query: 312 WGPRTLGLELRGVRAGDSGRYTCRAENRLGSQQQALDLSVQ 352
T LEL + A + G +TCR ++ LGSQ + LSVQ
Sbjct: 299 SMSGT--LELPNIGAREGGEFTCRVQHPLGSQHLSFILSVQ 337
Score = 123 bits (309), Expect = 5e-28
Identities = 81/200 (40%), Positives = 109/200 (54%), Gaps = 13/200 (6%)
Query: 264 SALELQGNVIYLE-VQKGQFLRLLCA----ADSQPPATLSWVLQDRVLSSSHPWGPRTLG 318
+AL + ++ +LE ++ G+ RL C+ ++ PP T SW LS P R+
Sbjct: 140 TALIEKPDIHFLEPLESGRPTRLSCSLPGSCEAGPPLTFSWT--GNALSPLDPETTRSSE 197
Query: 319 LELRGVRAGDSGRYTCRAENRLGSQ---QQALDLSVQYPPENLRVMVSQANRT--VLENL 373
L L TC+ + R G+Q ++ + L+V Y P+NL + + N T L L
Sbjct: 198 LTLTPRPEDHGTNLTCQVK-RQGAQVTTERTVQLNVSYAPQNLAISIFFRNGTGTALRIL 256
Query: 374 GNGTSLPVLEGQSLRLVCVTHSSPPARLSWTRWGQTVGPSQPSDPGVLELPPIQMEHEGE 433
NG S+P+ EGQSL L C S+PPA LSW R G+ + PSQ S G LELP I GE
Sbjct: 257 SNGMSVPIQEGQSLFLACTVDSNPPASLSWFREGKALNPSQTSMSGTLELPNIGAREGGE 316
Query: 434 FTCHAQHPLGSQHVSLSLSV 453
FTC QHPLGSQH+S LSV
Sbjct: 317 FTCRVQHPLGSQHLSFILSV 336
Score = 40.4 bits (93), Expect = 0.006
Identities = 56/225 (24%), Positives = 82/225 (36%), Gaps = 53/225 (23%)
Query: 315 RTLGLELRGVRAGDSGRYTCRAEN----RLGSQQQALDLSVQYPPENLRVMVSQANRTVL 370
+ L + R D+G Y R E + QQ L+L V ++ + + L
Sbjct: 99 KNCSLSIGDARMEDTGSYFFRVERGRDVKYSYQQNKLNLEVT-------ALIEKPDIHFL 151
Query: 371 ENLGNGTSLPVLEGQSLRLVCVTHSS----PPARLSWTRWGQTVGPSQPSDP--GVLELP 424
E P+ G+ RL C S PP SWT G + P P L L
Sbjct: 152 E--------PLESGRPTRLSCSLPGSCEAGPPLTFSWT--GNALSPLDPETTRSSELTLT 201
Query: 425 PIQMEHEGEFTCHAQHPLGSQHVS---LSLSVHYPPQLLGPSCSW--------------- 466
P +H TC + G+Q + + L+V Y PQ L S +
Sbjct: 202 PRPEDHGTNLTCQVKRQ-GAQVTTERTVQLNVSYAPQNLAISIFFRNGTGTALRILSNGM 260
Query: 467 -----EAEGLHCSCSSQASPAPSLRWWLGEELLEGNSSQGSFEVT 506
E + L +C+ ++P SL W+ + L N SQ S T
Sbjct: 261 SVPIQEGQSLFLACTVDSNPPASLSWFREGKAL--NPSQTSMSGT 303
>gi|94538343 sialic acid binding Ig-like lectin 8 [Homo sapiens]
Length = 499
Score = 271 bits (694), Expect = 1e-72
Identities = 165/379 (43%), Positives = 208/379 (54%), Gaps = 33/379 (8%)
Query: 13 MLLLPLLLPVL-GAGSLNKDPSYS----LQVQRQVPVPEGLCVIVSCNLSYPRDGWDEST 67
MLLL LLLP+L G + D Y LQVQ V V EGLCV V C+ SYP+DGW +S
Sbjct: 1 MLLLLLLLPLLWGTKGMEGDRQYGDGYLLQVQELVTVQEGLCVHVPCSFSYPQDGWTDSD 60
Query: 68 AAYGYWFKGRTSPKTGAPVATNNQSREVEMSTRDRFQLTGDPGKGSCSLVIRDAQREDEA 127
+GYWF+ P APVATNN REV+ T+ RFQL GD CSL IRDA++ D+
Sbjct: 61 PVHGYWFRAGDRPYQDAPVATNNPDREVQAETQGRFQLLGDIWSNDCSLSIRDARKRDKG 120
Query: 128 WYFFRVERGS-----RVRHSFLSNAFFLKVTALTKKPDVYIPETLEPGQPVTVICVFNWA 182
YFFR+ERGS + + ++ + + VTALT +PD+ I TLE G + C WA
Sbjct: 121 SYFFRLERGSMKWSYKSQLNYKTKQLSVFVTALTHRPDILILGTLESGHSRNLTCSVPWA 180
Query: 183 FKKCPAPSFSWTGAALSPRRTRPSTSHFSVLSFTPSPQDHDTDLTCHVDFSRKGVSAQRT 242
K+ P SW GA++S P+T+ SVL+ TP PQDH T LTC V GV+ T
Sbjct: 181 CKQGTPPMISWIGASVSS--PGPTTARSSVLTLTPKPQDHGTSLTCQVTLPGTGVTTTST 238
Query: 243 VRLRVAYAPKDLIISISHDNTSALELQGNVIYLEVQKGQFLRLLCAADSQPPATLSWVLQ 302
VRL V+Y P +L +++ + +A GN L V +GQ LRL+CA +S PPA LSW
Sbjct: 239 VRLDVSYPPWNLTMTVFQGDATASTALGNGSSLSVLEGQSLRLVCAVNSNPPARLSWTRG 298
Query: 303 DRVLSSSHPWGPRTLGLELRGVRAGDSGRYTCRAENRLGSQQQALDLSVQYPPENLRVMV 362
L S P L EL V D G +TCRA+N GSQ +L LS
Sbjct: 299 SLTLCPSRSSNPGLL--ELPRVHVRDEGEFTCRAQNAQGSQHISLSLS------------ 344
Query: 363 SQANRTVLENLGNGTSLPV 381
L+N G GTS PV
Sbjct: 345 -------LQNEGTGTSRPV 356
Score = 130 bits (328), Expect = 3e-30
Identities = 86/223 (38%), Positives = 121/223 (54%), Gaps = 14/223 (6%)
Query: 238 SAQRTVRLRVAYAPKDLIISISHDNTSALELQGNVIYL-EVQKGQFLRLLC----AADSQ 292
S + + + ++ Y K L + ++ AL + +++ L ++ G L C A
Sbjct: 130 SMKWSYKSQLNYKTKQLSVFVT-----ALTHRPDILILGTLESGHSRNLTCSVPWACKQG 184
Query: 293 PPATLSWVLQDRVLSSSHPWGPRTLGLELRGVRAGDSGRYTCRAE--NRLGSQQQALDLS 350
P +SW+ +SS P R+ L L TC+ + + L
Sbjct: 185 TPPMISWI--GASVSSPGPTTARSSVLTLTPKPQDHGTSLTCQVTLPGTGVTTTSTVRLD 242
Query: 351 VQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPPARLSWTRWGQTV 410
V YPP NL + V Q + T LGNG+SL VLEGQSLRLVC +S+PPARLSWTR T+
Sbjct: 243 VSYPPWNLTMTVFQGDATASTALGNGSSLSVLEGQSLRLVCAVNSNPPARLSWTRGSLTL 302
Query: 411 GPSQPSDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSV 453
PS+ S+PG+LELP + + EGEFTC AQ+ GSQH+SLSLS+
Sbjct: 303 CPSRSSNPGLLELPRVHVRDEGEFTCRAQNAQGSQHISLSLSL 345
Score = 101 bits (251), Expect = 3e-21
Identities = 118/395 (29%), Positives = 160/395 (40%), Gaps = 66/395 (16%)
Query: 319 LELRGVRAGDSGRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTS 378
L +R R D G Y R E GS + + + Y + L V V T L + +
Sbjct: 109 LSIRDARKRDKGSYFFRLER--GSMKWSYKSQLNYKTKQLSVFV-----TALTHRPDILI 161
Query: 379 LPVLE-GQSLRLVC----VTHSSPPARLSWTRWGQTVGPSQPSDP--GVLELPPIQMEHE 431
L LE G S L C P +SW G +V P+ VL L P +H
Sbjct: 162 LGTLESGHSRNLTCSVPWACKQGTPPMISWI--GASVSSPGPTTARSSVLTLTPKPQDHG 219
Query: 432 GEFTCHAQHPLGSQHVSLS---LSVHYPPQLL-----------------GPSCS-WEAEG 470
TC P G+ + S L V YPP L G S S E +
Sbjct: 220 TSLTCQVTLP-GTGVTTTSTVRLDVSYPPWNLTMTVFQGDATASTALGNGSSLSVLEGQS 278
Query: 471 LHCSCSSQASPAPSLRWWLGEELLEGNSSQGSFEVTPS-SAGPWANSSLSLHGGLSSGLR 529
L C+ ++P L W ++GS + PS S+ P +H +
Sbjct: 279 LRLVCAVNSNPPARLSW-----------TRGSLTLCPSRSSNPGLLELPRVH--VRDEGE 325
Query: 530 LRCKAWNVHGAQSGSVFQLLP----GKLEHGGGLGLGAALGAGVAALLAFCSCLVVFRVK 585
C+A N G+Q S+ L G + L A GAG AL C++ V+
Sbjct: 326 FTCRAQNAQGSQHISLSLSLQNEGTGTSRPVSQVTLAAVGGAGATALAFLSFCIIFIIVR 385
Query: 586 ICRKEARKRAAAE-----QDVPSTLGPISQGHQHEC-SAGSSQDHPPPGAATYTPGKGEE 639
CRK++ + AA +D + G SQG E G+ PPP A P GEE
Sbjct: 386 SCRKKSARPAAGVGDTGMEDAKAIRGSASQGPLTESWKDGNPLKKPPPAVA---PSSGEE 442
Query: 640 QELHYASLSFQGLRLWEPADQEAPSTTEYSEIKIH 674
ELHYA+LSF ++ +P QEA + +EYSEIKIH
Sbjct: 443 GELHYATLSFHKVKPQDPQGQEA-TDSEYSEIKIH 476
>gi|7657570 sialic acid binding Ig-like lectin 7 isoform 1 [Homo
sapiens]
Length = 467
Score = 264 bits (675), Expect = 2e-70
Identities = 147/344 (42%), Positives = 199/344 (57%), Gaps = 11/344 (3%)
Query: 14 LLLPLLLPVLGA-----GSLNKDPSYSLQVQRQVPVPEGLCVIVSCNLSYPRDGWDESTA 68
+LL LLLP+L G + YSL +Q V V EG+CV V C+ SYP D +S
Sbjct: 1 MLLLLLLPLLWGRERVEGQKSNRKDYSLTMQSSVTVQEGMCVHVRCSFSYPVDSQTDSDP 60
Query: 69 AYGYWFKGRTSPKTGAPVATNNQSREVEMSTRDRFQLTGDPGKGSCSLVIRDAQREDEAW 128
+GYWF+ APVATNN + V+ TRDRF L GDP +C+L IRDA+ D
Sbjct: 61 VHGYWFRAGNDISWKAPVATNNPAWAVQEETRDRFHLLGDPQTKNCTLSIRDARMSDAGR 120
Query: 129 YFFRVERGSRVRHSFLSNAFFLKVTALTKKPDVYIPETLEPGQPVTVICVFNWAFKKCPA 188
YFFR+E+G+ ++ ++ + + VTALT +P++ IP TLE G + C WA ++
Sbjct: 121 YFFRMEKGN-IKWNYKYDQLSVNVTALTHRPNILIPGTLESGCFQNLTCSVPWACEQGTP 179
Query: 189 PSFSWTGAALSPRRTRPSTSHFSVLSFTPSPQDHDTDLTCHVDFSRKGVSAQRTVRLRVA 248
P SW G ++SP PST+ SVL+ P PQ H T LTC V GV+ RT++L V+
Sbjct: 180 PMISWMGTSVSP--LHPSTTRSSVLTLIPQPQHHGTSLTCQVTLPGAGVTTNRTIQLNVS 237
Query: 249 YAPKDLIISISHDNTSALELQGNVIYLEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSS 308
Y P++L +++ +A GN L V +GQ LRL+CA DS PPA LSW + L
Sbjct: 238 YPPQNLTVTVFQGEGTASTALGNSSSLSVLEGQSLRLVCAVDSNPPARLSWTWRSLTLYP 297
Query: 309 SHPWGPRTLGLELRGVRAGDSGRYTCRAENRLGSQQQALDLSVQ 352
S P P L L+ V GD G +TCRA+N LGSQ +L+LS+Q
Sbjct: 298 SQPSNPLVLELQ---VHLGDEGEFTCRAQNSLGSQHVSLNLSLQ 338
Score = 128 bits (322), Expect = 2e-29
Identities = 85/199 (42%), Positives = 111/199 (55%), Gaps = 10/199 (5%)
Query: 262 NTSALELQGNVIYL-EVQKGQFLRLLC----AADSQPPATLSWVLQDRVLSSSHPWGPRT 316
N +AL + N++ ++ G F L C A + P +SW+ +S HP R+
Sbjct: 142 NVTALTHRPNILIPGTLESGCFQNLTCSVPWACEQGTPPMISWM--GTSVSPLHPSTTRS 199
Query: 317 LGLELRGVRAGDSGRYTCRAE--NRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLG 374
L L TC+ + + + L+V YPP+NL V V Q T LG
Sbjct: 200 SVLTLIPQPQHHGTSLTCQVTLPGAGVTTNRTIQLNVSYPPQNLTVTVFQGEGTASTALG 259
Query: 375 NGTSLPVLEGQSLRLVCVTHSSPPARLSWTRWGQTVGPSQPSDPGVLELPPIQMEHEGEF 434
N +SL VLEGQSLRLVC S+PPARLSWT T+ PSQPS+P VLEL + + EGEF
Sbjct: 260 NSSSLSVLEGQSLRLVCAVDSNPPARLSWTWRSLTLYPSQPSNPLVLEL-QVHLGDEGEF 318
Query: 435 TCHAQHPLGSQHVSLSLSV 453
TC AQ+ LGSQHVSL+LS+
Sbjct: 319 TCRAQNSLGSQHVSLNLSL 337
Score = 94.4 bits (233), Expect = 3e-19
Identities = 115/411 (27%), Positives = 167/411 (40%), Gaps = 64/411 (15%)
Query: 298 SWVLQDRVLSSSHPWG-PRTLG--LELRGVRAGDSGRYTCRAENRLGSQQQALD-LSVQY 353
+W +Q+ H G P+T L +R R D+GRY R E D LSV
Sbjct: 84 AWAVQEETRDRFHLLGDPQTKNCTLSIRDARMSDAGRYFFRMEKGNIKWNYKYDQLSV-- 141
Query: 354 PPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPPARLSWTRWGQTVGPS 413
N+ + + N + L +G + + + P +SW G +V P
Sbjct: 142 ---NVTALTHRPNILIPGTLESGC----FQNLTCSVPWACEQGTPPMISWM--GTSVSPL 192
Query: 414 QPSDP--GVLELPPIQMEHEGEFTCHAQHPLG--SQHVSLSLSVHYPPQ----------- 458
PS VL L P H TC P + + ++ L+V YPPQ
Sbjct: 193 HPSTTRSSVLTLIPQPQHHGTSLTCQVTLPGAGVTTNRTIQLNVSYPPQNLTVTVFQGEG 252
Query: 459 ----LLGPSCSW---EAEGLHCSCSSQASPAPSLRWWLGEELLEGNSSQGSFEVTPSSAG 511
LG S S E + L C+ ++P L W + S + PS
Sbjct: 253 TASTALGNSSSLSVLEGQSLRLVCAVDSNPPARLSW-----------TWRSLTLYPSQPS 301
Query: 512 PWANSSLSLHGGLSSGLRLRCKAWNVHGAQ----SGSVFQLLPGKLEHGGGLGLGAALGA 567
L +H G C+A N G+Q + S+ Q GK+ G+ LGA GA
Sbjct: 302 NPLVLELQVHLGDEG--EFTCRAQNSLGSQHVSLNLSLQQEYTGKMRPVSGVLLGAVGGA 359
Query: 568 GVAALLAFCSCLVVFRVKICRKEARKRAA-----AEQDVPSTLGPISQGHQHECSAGSSQ 622
G AL+ C++ V+ CRK++ + AA +D + G SQG+ E A +
Sbjct: 360 GATALVFLSFCVIFIVVRSCRKKSARPAADVGDIGMKDANTIRGSASQGNLTESWADDNP 419
Query: 623 DHPPPGAATYTPGKGEEQELHYASLSFQGLRLWEPADQEAPSTTEYSEIKI 673
H G A ++ GEE+E+ YA LSF + + QEA + EYSEIKI
Sbjct: 420 RH--HGLAAHS--SGEEREIQYAPLSFHKGEPQDLSGQEA-TNNEYSEIKI 465
>gi|23943856 sialic acid binding Ig-like lectin 9 [Homo sapiens]
Length = 463
Score = 250 bits (638), Expect = 4e-66
Identities = 147/343 (42%), Positives = 197/343 (57%), Gaps = 10/343 (2%)
Query: 15 LLPLLLPVL-GAGSLNKDPSYSLQVQRQVPVPEGLCVIVSCNLSYPRDGWD-ESTAAYGY 72
+L LLLP+L G S L +Q V V EGLCV V C+ SYP GW +GY
Sbjct: 1 MLLLLLPLLWGRERAEGQTSKLLTMQSSVTVQEGLCVHVPCSFSYPSHGWIYPGPVVHGY 60
Query: 73 WFKGRTSPKTGAPVATNNQSREVEMSTRDRFQLTGDPGKGSCSLVIRDAQREDEAWYFFR 132
WF+ + APVATNN +R V TRDRF L GDP +C+L IRDA+R D YFFR
Sbjct: 61 WFREGANTDQDAPVATNNPARAVWEETRDRFHLLGDPHTKNCTLSIRDARRSDAGRYFFR 120
Query: 133 VERGSRVRHSFLSNAFFLKVTALTKKPDVYIPETLEPGQPVTVICVFNWAFKKCPAPSFS 192
+E+GS ++ ++ + + VTALT +P++ IP TLE G P + C WA ++ P S
Sbjct: 121 MEKGS-IKWNYKHHRLSVNVTALTHRPNILIPGTLESGCPQNLTCSVPWACEQGTPPMIS 179
Query: 193 WTGAALSPRRTRPSTSHFSVLSFTPSPQDHDTDLTCHVDFSRKGVSAQRTVRLRVAYAPK 252
W G ++SP PST+ SVL+ P PQDH T LTC V F V+ +TV L V+Y P+
Sbjct: 180 WIGTSVSP--LDPSTTRSSVLTLIPQPQDHGTSLTCQVTFPGASVTTNKTVHLNVSYPPQ 237
Query: 253 DLIISISHDNTSALELQGNVIYLEVQKGQFLRLLC---AADSQPPATLSWVLQDRVLSSS 309
+L +++ + + + GN L + +GQ LRL+C A DS PPA LS + L S
Sbjct: 238 NLTMTVFQGDGTVSTVLGNGSSLSLPEGQSLRLVCAVDAVDSNPPARLSLSWRGLTLCPS 297
Query: 310 HPWGPRTLGLELRGVRAGDSGRYTCRAENRLGSQQQALDLSVQ 352
P P LEL V D+ +TCRA+N LGSQQ L++S+Q
Sbjct: 298 QPSNPGV--LELPWVHLRDAAEFTCRAQNPLGSQQVYLNVSLQ 338
Score = 114 bits (285), Expect = 3e-25
Identities = 80/202 (39%), Positives = 110/202 (54%), Gaps = 12/202 (5%)
Query: 262 NTSALELQGNVIYL-EVQKGQFLRLLC----AADSQPPATLSWVLQDRVLSSSHPWGPRT 316
N +AL + N++ ++ G L C A + P +SW+ +S P R+
Sbjct: 138 NVTALTHRPNILIPGTLESGCPQNLTCSVPWACEQGTPPMISWI--GTSVSPLDPSTTRS 195
Query: 317 LGLELRGVRAGDSGRYTCRAENRLGS--QQQALDLSVQYPPENLRVMVSQANRTVLENLG 374
L L TC+ S + + L+V YPP+NL + V Q + TV LG
Sbjct: 196 SVLTLIPQPQDHGTSLTCQVTFPGASVTTNKTVHLNVSYPPQNLTMTVFQGDGTVSTVLG 255
Query: 375 NGTSLPVLEGQSLRLVCVTH---SSPPARLSWTRWGQTVGPSQPSDPGVLELPPIQMEHE 431
NG+SL + EGQSLRLVC S+PPARLS + G T+ PSQPS+PGVLELP + +
Sbjct: 256 NGSSLSLPEGQSLRLVCAVDAVDSNPPARLSLSWRGLTLCPSQPSNPGVLELPWVHLRDA 315
Query: 432 GEFTCHAQHPLGSQHVSLSLSV 453
EFTC AQ+PLGSQ V L++S+
Sbjct: 316 AEFTCRAQNPLGSQQVYLNVSL 337
Score = 102 bits (255), Expect = 9e-22
Identities = 122/394 (30%), Positives = 161/394 (40%), Gaps = 73/394 (18%)
Query: 319 LELRGVRAGDSGRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTS 378
L +R R D+GRY R E S+++ ++ R+ V N T L + N
Sbjct: 104 LSIRDARRSDAGRYFFRMEKG----------SIKWNYKHHRLSV---NVTALTHRPNILI 150
Query: 379 LPVLE-GQSLRLVC----VTHSSPPARLSWTRWGQTVGPSQPSDP--GVLELPPIQMEHE 431
LE G L C P +SW G +V P PS VL L P +H
Sbjct: 151 PGTLESGCPQNLTCSVPWACEQGTPPMISWI--GTSVSPLDPSTTRSSVLTLIPQPQDHG 208
Query: 432 GEFTCHAQHPLGS--QHVSLSLSVHYPPQLL-----------------GPSCSW-EAEGL 471
TC P S + ++ L+V YPPQ L G S S E + L
Sbjct: 209 TSLTCQVTFPGASVTTNKTVHLNVSYPPQNLTMTVFQGDGTVSTVLGNGSSLSLPEGQSL 268
Query: 472 HCSCSSQA----SPAPSLRWWLGEELLEGN-SSQGSFEVTPSSAGPWANSSLSLHGGLSS 526
C+ A PA W G L S+ G E+ PW + L
Sbjct: 269 RLVCAVDAVDSNPPARLSLSWRGLTLCPSQPSNPGVLEL------PWVH--------LRD 314
Query: 527 GLRLRCKAWNVHGAQSGSVFQLLPGKLEHGGGLGLGAALGAGVAALLAFCSCLVVFRVKI 586
C+A N G+Q + L K G G+ GA L+FC VV V+
Sbjct: 315 AAEFTCRAQNPLGSQQVYLNVSLQSKATSGVTQGVVGGAGATALVFLSFCVIFVV--VRS 372
Query: 587 CRKEARKRAAAE-----QDVPSTLGPISQGHQHECSAGSSQ-DHPPPGAATYTPGKGEEQ 640
CRK++ + AA +D + G SQG E A S D PPP +A + G+GE
Sbjct: 373 CRKKSARPAAGVGDTGIEDANAVRGSASQGPLTEPWAEDSPPDQPPPASARSSVGEGE-- 430
Query: 641 ELHYASLSFQGLRLWEPADQEAPSTTEYSEIKIH 674
L YASLSFQ ++ W+ QEA + TEYSEIKIH
Sbjct: 431 -LQYASLSFQMVKPWDSRGQEA-TDTEYSEIKIH 462
>gi|193794821 sialic acid binding Ig-like lectin 6 isoform 1
precursor [Homo sapiens]
Length = 453
Score = 248 bits (634), Expect = 1e-65
Identities = 145/342 (42%), Positives = 199/342 (58%), Gaps = 12/342 (3%)
Query: 15 LLPLLLPVLGAGSLNKDPSYSLQVQRQVPVPEGLCVIVSCNLSYPRDGWDESTAAYGYWF 74
+LPLLLP+L AG+L ++ + L+ + V EGLCV+V C L S YGYWF
Sbjct: 12 MLPLLLPLLWAGALAQERRFQLEGPESLTVQEGLCVLVPCRLPTTLPA---SYYGYGYWF 68
Query: 75 KGRTSPKTGAPVATNNQSREVEMSTRDRFQLTGDPGKGSCSLVIRDAQREDEAWYFFRVE 134
PVATN+ EV+ TR RF L DP + +CSL IRDA+R D A YFFR+
Sbjct: 69 LEGAD----VPVATNDPDEEVQEETRGRFHLLWDPRRKNCSLSIRDARRRDNAAYFFRL- 123
Query: 135 RGSRVRHSFLSNAFFLKVTALTKKPDVYIPETLEPGQPVTVICVFNWAFKKCPAPSFSWT 194
+ +++ + S+ ++V ALT +P++ IP TLE G P + C W ++ P FSW
Sbjct: 124 KSKWMKYGYTSSKLSVRVMALTHRPNISIPGTLESGHPSNLTCSVPWVCEQGTPPIFSWM 183
Query: 195 GAALSPRRTRPSTSHFSVLSFTPSPQDHDTDLTCHVDFSRKGVSAQRTVRLRVAYAPKDL 254
AA P P T+ SVL+ TP PQDH T+LTC V F GV+ +RT++L V+YAP+ +
Sbjct: 184 SAA--PTSLGPRTTQSSVLTITPRPQDHSTNLTCQVTFPGAGVTMERTIQLNVSYAPQKV 241
Query: 255 IISISHDNTSALELQGNVIYLEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGP 314
ISI N++A ++ N L V +GQ LRLLC AD PPA LSW L+++
Sbjct: 242 AISIFQGNSAAFKILQNTSSLPVLEGQALRLLCDADGNPPAHLSWFQGFPALNATPI--S 299
Query: 315 RTLGLELRGVRAGDSGRYTCRAENRLGSQQQALDLSVQYPPE 356
T LEL V + + G +TCRA++ LGS Q +L L V + PE
Sbjct: 300 NTGVLELPQVGSAEEGDFTCRAQHPLGSLQISLSLFVHWKPE 341
Score = 110 bits (275), Expect = 4e-24
Identities = 52/117 (44%), Positives = 75/117 (64%)
Query: 342 SQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPPARL 401
+ ++ + L+V Y P+ + + + Q N + L N +SLPVLEGQ+LRL+C +PPA L
Sbjct: 225 TMERTIQLNVSYAPQKVAISIFQGNSAAFKILQNTSSLPVLEGQALRLLCDADGNPPAHL 284
Query: 402 SWTRWGQTVGPSQPSDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSVHYPPQ 458
SW + + + S+ GVLELP + EG+FTC AQHPLGS +SLSL VH+ P+
Sbjct: 285 SWFQGFPALNATPISNTGVLELPQVGSAEEGDFTCRAQHPLGSLQISLSLFVHWKPE 341
Score = 96.7 bits (239), Expect = 7e-20
Identities = 108/392 (27%), Positives = 149/392 (38%), Gaps = 65/392 (16%)
Query: 312 WGPR--TLGLELRGVRAGDSGRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTV 369
W PR L +R R D+ Y R +++ + Y L V V
Sbjct: 97 WDPRRKNCSLSIRDARRRDNAAYFFRLKSKW--------MKYGYTSSKLSVRVM-----A 143
Query: 370 LENLGNGTSLPVLE-GQSLRLVC----VTHSSPPARLSWTRWGQTVGPSQPSDPGVLELP 424
L + N + LE G L C V P SW T + + VL +
Sbjct: 144 LTHRPNISIPGTLESGHPSNLTCSVPWVCEQGTPPIFSWMSAAPTSLGPRTTQSSVLTIT 203
Query: 425 PIQMEHEGEFTCHAQHPLG--SQHVSLSLSVHYPPQLL------GPSCSW---------- 466
P +H TC P + ++ L+V Y PQ + G S ++
Sbjct: 204 PRPQDHSTNLTCQVTFPGAGVTMERTIQLNVSYAPQKVAISIFQGNSAAFKILQNTSSLP 263
Query: 467 --EAEGLHCSCSSQASPAPSLRWWLGEELLEGN--SSQGSFEVTPSSAGPWANSSLSLHG 522
E + L C + +P L W+ G L S+ G E L G
Sbjct: 264 VLEGQALRLLCDADGNPPAHLSWFQGFPALNATPISNTGVLE-------------LPQVG 310
Query: 523 GLSSGLRLRCKAWNVHGAQSGSVFQLLPGKLEHGGGLGLGAALGAGVAALLAFCSCLVVF 582
G C+A + G+ S+ + K E G LGA GA + L+ C C + F
Sbjct: 311 SAEEG-DFTCRAQHPLGSLQISLSLFVHWKPEGRAGGVLGAVWGASITTLVFLCVCFI-F 368
Query: 583 RVKICRKEARKRAAAEQDVPSTLGPISQGHQHECSAGSSQDHPPPGAATYTPGKGEEQEL 642
RVK RK+A + DV + S+GHQH+ G DHP A P +EQEL
Sbjct: 369 RVKTRRKKAAQPVQNTDDVNPVMVSGSRGHQHQFQTGIVSDHP----AEAGPISEDEQEL 424
Query: 643 HYASLSFQGLRLWEPADQEAPSTTEYSEIKIH 674
HYA L F ++ EP + TEYSEIKIH
Sbjct: 425 HYAVLHFHKVQPQEP----KVTDTEYSEIKIH 452
>gi|193794817 sialic acid binding Ig-like lectin 6 isoform 3
precursor [Homo sapiens]
Length = 353
Score = 244 bits (623), Expect = 2e-64
Identities = 143/339 (42%), Positives = 197/339 (58%), Gaps = 12/339 (3%)
Query: 15 LLPLLLPVLGAGSLNKDPSYSLQVQRQVPVPEGLCVIVSCNLSYPRDGWDESTAAYGYWF 74
+LPLLLP+L AG+L ++ + L+ + V EGLCV+V C L S YGYWF
Sbjct: 12 MLPLLLPLLWAGALAQERRFQLEGPESLTVQEGLCVLVPCRLPTTLPA---SYYGYGYWF 68
Query: 75 KGRTSPKTGAPVATNNQSREVEMSTRDRFQLTGDPGKGSCSLVIRDAQREDEAWYFFRVE 134
PVATN+ EV+ TR RF L DP + +CSL IRDA+R D A YFFR+
Sbjct: 69 LEGAD----VPVATNDPDEEVQEETRGRFHLLWDPRRKNCSLSIRDARRRDNAAYFFRL- 123
Query: 135 RGSRVRHSFLSNAFFLKVTALTKKPDVYIPETLEPGQPVTVICVFNWAFKKCPAPSFSWT 194
+ +++ + S+ ++V ALT +P++ IP TLE G P + C W ++ P FSW
Sbjct: 124 KSKWMKYGYTSSKLSVRVMALTHRPNISIPGTLESGHPSNLTCSVPWVCEQGTPPIFSWM 183
Query: 195 GAALSPRRTRPSTSHFSVLSFTPSPQDHDTDLTCHVDFSRKGVSAQRTVRLRVAYAPKDL 254
AA P P T+ SVL+ TP PQDH T+LTC V F GV+ +RT++L V+YAP+ +
Sbjct: 184 SAA--PTSLGPRTTQSSVLTITPRPQDHSTNLTCQVTFPGAGVTMERTIQLNVSYAPQKV 241
Query: 255 IISISHDNTSALELQGNVIYLEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGP 314
ISI N++A ++ N L V +GQ LRLLC AD PPA LSW L+++
Sbjct: 242 AISIFQGNSAAFKILQNTSSLPVLEGQALRLLCDADGNPPAHLSWFQGFPALNATPI--S 299
Query: 315 RTLGLELRGVRAGDSGRYTCRAENRLGSQQQALDLSVQY 353
T LEL V + + G +TCRA++ LGS Q +L L V +
Sbjct: 300 NTGVLELPQVGSAEEGDFTCRAQHPLGSLQISLSLFVHW 338
Score = 107 bits (267), Expect = 4e-23
Identities = 51/114 (44%), Positives = 73/114 (64%)
Query: 342 SQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPPARL 401
+ ++ + L+V Y P+ + + + Q N + L N +SLPVLEGQ+LRL+C +PPA L
Sbjct: 225 TMERTIQLNVSYAPQKVAISIFQGNSAAFKILQNTSSLPVLEGQALRLLCDADGNPPAHL 284
Query: 402 SWTRWGQTVGPSQPSDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSVHY 455
SW + + + S+ GVLELP + EG+FTC AQHPLGS +SLSL VH+
Sbjct: 285 SWFQGFPALNATPISNTGVLELPQVGSAEEGDFTCRAQHPLGSLQISLSLFVHW 338
Score = 33.9 bits (76), Expect = 0.52
Identities = 46/206 (22%), Positives = 69/206 (33%), Gaps = 40/206 (19%)
Query: 312 WGPR--TLGLELRGVRAGDSGRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTV 369
W PR L +R R D+ Y R +++ + Y L V V
Sbjct: 97 WDPRRKNCSLSIRDARRRDNAAYFFRLKSKW--------MKYGYTSSKLSVRVM-----A 143
Query: 370 LENLGNGTSLPVLE-GQSLRLVC----VTHSSPPARLSWTRWGQTVGPSQPSDPGVLELP 424
L + N + LE G L C V P SW T + + VL +
Sbjct: 144 LTHRPNISIPGTLESGHPSNLTCSVPWVCEQGTPPIFSWMSAAPTSLGPRTTQSSVLTIT 203
Query: 425 PIQMEHEGEFTCHAQHPLG--SQHVSLSLSVHYPPQLL------GPSCSW---------- 466
P +H TC P + ++ L+V Y PQ + G S ++
Sbjct: 204 PRPQDHSTNLTCQVTFPGAGVTMERTIQLNVSYAPQKVAISIFQGNSAAFKILQNTSSLP 263
Query: 467 --EAEGLHCSCSSQASPAPSLRWWLG 490
E + L C + +P L W+ G
Sbjct: 264 VLEGQALRLLCDADGNPPAHLSWFQG 289
>gi|16506826 sialic acid binding immunoglobulin-like lectin-like
protein 1 isoform b precursor [Homo sapiens]
Length = 477
Score = 239 bits (609), Expect = 8e-63
Identities = 137/320 (42%), Positives = 180/320 (56%), Gaps = 7/320 (2%)
Query: 34 YSLQVQRQVPVPEGLCVIVSCNLSYPRDGWDESTAAYGYWFKGRTSPKTGAPVATNNQSR 93
Y L+V V V EGLCV V C++ YP W S+ YG WFK PVATN S
Sbjct: 33 YRLEVPESVTVQEGLCVSVPCSVLYPHYNWTASSPVYGSWFKEGADIPWDIPVATNTPSG 92
Query: 94 EVEMSTRDRFQLTGDPGKGSCSLVIRDAQREDEAWYFFRVERGSRVRHSFLSNAFFLKVT 153
+V+ T RF L GDP +CSL IRDA++ D Y+F+VERGSR + +++ + + VT
Sbjct: 93 KVQEDTHGRFLLLGDPQTNNCSLSIRDARKGDSGKYYFQVERGSR-KWNYIYDKLSVHVT 151
Query: 154 ALTKKPDVYIPETLEPGQPVTVICVFNWAFKKCPAPSFSWTGAALSPRRTRPSTSHFSVL 213
ALT P IP TLE G P + C WA ++ P+ +W GA++S P+ + S+L
Sbjct: 152 ALTHMPTFSIPGTLESGHPRNLTCSVPWACEQGTPPTITWMGASVS--SLDPTITRSSML 209
Query: 214 SFTPSPQDHDTDLTCHVDFSRKGVSAQRTVRLRVAYAPKDLIISISHDNTSALELQGNVI 273
S P PQDH T LTC V GV+ R VRL ++Y P++L +++ + +A N
Sbjct: 210 SLIPQPQDHGTSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGS 269
Query: 274 YLEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLG-LELRGVRAGDSGRY 332
L V +GQ L L+CA DS PPA LSW LS S LG LEL V D G +
Sbjct: 270 ALSVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPSQ---SSNLGVLELPRVHVKDEGEF 326
Query: 333 TCRAENRLGSQQQALDLSVQ 352
TCRA+N LGSQ +L LS+Q
Sbjct: 327 TCRAQNPLGSQHISLSLSLQ 346
Score = 130 bits (327), Expect = 4e-30
Identities = 75/168 (44%), Positives = 101/168 (60%), Gaps = 4/168 (2%)
Query: 288 AADSQPPATLSWVLQDRVLSSSHPWGPRTLGLELRGVRAGDSGRYTCRAE--NRLGSQQQ 345
A + P T++W+ +SS P R+ L L TC+ + +
Sbjct: 180 ACEQGTPPTITWM--GASVSSLDPTITRSSMLSLIPQPQDHGTSLTCQVTLPGAGVTMTR 237
Query: 346 ALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPPARLSWTR 405
A+ L++ YPP+NL + V Q + T L NG++L VLEGQSL LVC S+PPARLSWT
Sbjct: 238 AVRLNISYPPQNLTMTVFQGDGTASTTLRNGSALSVLEGQSLHLVCAVDSNPPARLSWTW 297
Query: 406 WGQTVGPSQPSDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSV 453
T+ PSQ S+ GVLELP + ++ EGEFTC AQ+PLGSQH+SLSLS+
Sbjct: 298 GSLTLSPSQSSNLGVLELPRVHVKDEGEFTCRAQNPLGSQHISLSLSL 345
Score = 92.4 bits (228), Expect = 1e-18
Identities = 113/392 (28%), Positives = 159/392 (40%), Gaps = 68/392 (17%)
Query: 319 LELRGVRAGDSGRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTS 378
L +R R GDSG+Y + E GS++ Y + L V V T L ++ +
Sbjct: 115 LSIRDARKGDSGKYYFQVER--GSRKW------NYIYDKLSVHV-----TALTHMPTFSI 161
Query: 379 LPVLE-GQSLRLVC----VTHSSPPARLSWTRWGQTVGPSQPS--DPGVLELPPIQMEHE 431
LE G L C P ++W G +V P+ +L L P +H
Sbjct: 162 PGTLESGHPRNLTCSVPWACEQGTPPTITWM--GASVSSLDPTITRSSMLSLIPQPQDHG 219
Query: 432 GEFTCHAQHPLGSQHVS--LSLSVHYPPQLL-----------------GPSCS-WEAEGL 471
TC P ++ + L++ YPPQ L G + S E + L
Sbjct: 220 TSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSALSVLEGQSL 279
Query: 472 HCSCSSQASPAPSLRWWLGEELLEGNSSQGSFEVTPSSAGPWANSSLSLHGGLSSGLRLR 531
H C+ ++P L W + GS ++PS + L G
Sbjct: 280 HLVCAVDSNPPARLSW-----------TWGSLTLSPSQSSNLGVLELPRVHVKDEG-EFT 327
Query: 532 CKAWNVHGAQSGSVFQLLP----GKLEHGGGLGLGAALGAGVAALLAFCSCLVVFRVKIC 587
C+A N G+Q S+ L GK+ G+ LGA GAG AL+ C++ V+ C
Sbjct: 328 CRAQNPLGSQHISLSLSLQNEYTGKMRPISGVTLGAFGGAGATALVFLYFCIIFVVVRSC 387
Query: 588 RKEARKRA-----AAEQDVPSTLGPISQGHQHECSAGSS-QDHPPPGAATYTPGKGEEQE 641
RK++ + A +D + G SQG E A S H PP AT +P EE E
Sbjct: 388 RKKSARPAVGVGDTGMEDANAVRGSASQGPLIESPADDSPPHHAPPALATPSP---EEGE 444
Query: 642 LHYASLSFQGLRLWEPADQEAPSTTEYSEIKI 673
+ YASLSF R P +QEA EYSEI I
Sbjct: 445 IQYASLSFHKARPQYPQEQEAIG-YEYSEINI 475
>gi|16506828 sialic acid binding immunoglobulin-like lectin-like
protein 1 isoform a precursor [Homo sapiens]
Length = 595
Score = 239 bits (609), Expect = 8e-63
Identities = 137/320 (42%), Positives = 180/320 (56%), Gaps = 7/320 (2%)
Query: 34 YSLQVQRQVPVPEGLCVIVSCNLSYPRDGWDESTAAYGYWFKGRTSPKTGAPVATNNQSR 93
Y L+V V V EGLCV V C++ YP W S+ YG WFK PVATN S
Sbjct: 151 YRLEVPESVTVQEGLCVSVPCSVLYPHYNWTASSPVYGSWFKEGADIPWDIPVATNTPSG 210
Query: 94 EVEMSTRDRFQLTGDPGKGSCSLVIRDAQREDEAWYFFRVERGSRVRHSFLSNAFFLKVT 153
+V+ T RF L GDP +CSL IRDA++ D Y+F+VERGSR + +++ + + VT
Sbjct: 211 KVQEDTHGRFLLLGDPQTNNCSLSIRDARKGDSGKYYFQVERGSR-KWNYIYDKLSVHVT 269
Query: 154 ALTKKPDVYIPETLEPGQPVTVICVFNWAFKKCPAPSFSWTGAALSPRRTRPSTSHFSVL 213
ALT P IP TLE G P + C WA ++ P+ +W GA++S P+ + S+L
Sbjct: 270 ALTHMPTFSIPGTLESGHPRNLTCSVPWACEQGTPPTITWMGASVSS--LDPTITRSSML 327
Query: 214 SFTPSPQDHDTDLTCHVDFSRKGVSAQRTVRLRVAYAPKDLIISISHDNTSALELQGNVI 273
S P PQDH T LTC V GV+ R VRL ++Y P++L +++ + +A N
Sbjct: 328 SLIPQPQDHGTSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGS 387
Query: 274 YLEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLG-LELRGVRAGDSGRY 332
L V +GQ L L+CA DS PPA LSW LS S LG LEL V D G +
Sbjct: 388 ALSVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPSQS---SNLGVLELPRVHVKDEGEF 444
Query: 333 TCRAENRLGSQQQALDLSVQ 352
TCRA+N LGSQ +L LS+Q
Sbjct: 445 TCRAQNPLGSQHISLSLSLQ 464
Score = 233 bits (595), Expect = 3e-61
Identities = 169/469 (36%), Positives = 240/469 (51%), Gaps = 34/469 (7%)
Query: 13 MLLLPLLLPVLGAGSLN--KDPSYSLQVQRQVPVPEGLCVIVSCNLSYPRDGWDESTAAY 70
MLLL LLLP L G + + Y L +Q+ V V EGLCV V C+ SYP++GW S +
Sbjct: 1 MLLLLLLLPPLLCGRVGAKEQKDYLLTMQKSVTVQEGLCVSVLCSFSYPQNGWTASDPVH 60
Query: 71 GYWFKGRTSPKTGAPVATNNQSREVEMSTRDRFQLTGDPGKGSCSLVIRDAQREDEAWYF 130
GYWF+ PVATNN +R V+ TRDRF L GDP C+L IRD + D Y
Sbjct: 61 GYWFRAGDHVSRNIPVATNNPARAVQEETRDRFHLLGDPQNKDCTLSIRDTRESDAGTYV 120
Query: 131 FRVERGSRVRHSFLSNAFFLKVTA---LTKKPDVYIPE--TLEPGQPVTVICV-----FN 180
F VERG+ ++ ++ + + VTA L + + +PE T++ G V+V C +N
Sbjct: 121 FCVERGN-MKWNYKYDQLSVNVTASQDLLSRYRLEVPESVTVQEGLCVSVPCSVLYPHYN 179
Query: 181 WAFKKCPAPSFSWTGAAL---------SPRRTRPSTSHFSVLSFTPSPQDHDTDLTCHVD 231
W S+ GA + +P +H L PQ ++ L+ +
Sbjct: 180 WTASSPVYGSWFKEGADIPWDIPVATNTPSGKVQEDTHGRFL-LLGDPQTNNCSLS--IR 236
Query: 232 FSRKGVSAQRTVRLRVAYAPKDLIIS-ISHDNTSALELQGNVIYLEVQKGQFLRLLC--- 287
+RKG S + ++ + I +S T+ + I ++ G L C
Sbjct: 237 DARKGDSGKYYFQVERGSRKWNYIYDKLSVHVTALTHMPTFSIPGTLESGHPRNLTCSVP 296
Query: 288 -AADSQPPATLSWVLQDRVLSSSHPWGPRTLGLELRGVRAGDSGRYTCRAE--NRLGSQQ 344
A + P T++W+ +SS P R+ L L TC+ +
Sbjct: 297 WACEQGTPPTITWM--GASVSSLDPTITRSSMLSLIPQPQDHGTSLTCQVTLPGAGVTMT 354
Query: 345 QALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPPARLSWT 404
+A+ L++ YPP+NL + V Q + T L NG++L VLEGQSL LVC S+PPARLSWT
Sbjct: 355 RAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSALSVLEGQSLHLVCAVDSNPPARLSWT 414
Query: 405 RWGQTVGPSQPSDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSV 453
T+ PSQ S+ GVLELP + ++ EGEFTC AQ+PLGSQH+SLSLS+
Sbjct: 415 WGSLTLSPSQSSNLGVLELPRVHVKDEGEFTCRAQNPLGSQHISLSLSL 463
Score = 92.4 bits (228), Expect = 1e-18
Identities = 113/392 (28%), Positives = 159/392 (40%), Gaps = 68/392 (17%)
Query: 319 LELRGVRAGDSGRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTS 378
L +R R GDSG+Y + E GS++ Y + L V V T L ++ +
Sbjct: 233 LSIRDARKGDSGKYYFQVER--GSRKW------NYIYDKLSVHV-----TALTHMPTFSI 279
Query: 379 LPVLE-GQSLRLVC----VTHSSPPARLSWTRWGQTVGPSQPS--DPGVLELPPIQMEHE 431
LE G L C P ++W G +V P+ +L L P +H
Sbjct: 280 PGTLESGHPRNLTCSVPWACEQGTPPTITWM--GASVSSLDPTITRSSMLSLIPQPQDHG 337
Query: 432 GEFTCHAQHPLGSQHVS--LSLSVHYPPQLL-----------------GPSCS-WEAEGL 471
TC P ++ + L++ YPPQ L G + S E + L
Sbjct: 338 TSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSALSVLEGQSL 397
Query: 472 HCSCSSQASPAPSLRWWLGEELLEGNSSQGSFEVTPSSAGPWANSSLSLHGGLSSGLRLR 531
H C+ ++P L W + GS ++PS + L G
Sbjct: 398 HLVCAVDSNPPARLSW-----------TWGSLTLSPSQSSNLGVLELPRVHVKDEG-EFT 445
Query: 532 CKAWNVHGAQSGSVFQLLP----GKLEHGGGLGLGAALGAGVAALLAFCSCLVVFRVKIC 587
C+A N G+Q S+ L GK+ G+ LGA GAG AL+ C++ V+ C
Sbjct: 446 CRAQNPLGSQHISLSLSLQNEYTGKMRPISGVTLGAFGGAGATALVFLYFCIIFVVVRSC 505
Query: 588 RKEARKRA-----AAEQDVPSTLGPISQGHQHECSAGSS-QDHPPPGAATYTPGKGEEQE 641
RK++ + A +D + G SQG E A S H PP AT +P EE E
Sbjct: 506 RKKSARPAVGVGDTGMEDANAVRGSASQGPLIESPADDSPPHHAPPALATPSP---EEGE 562
Query: 642 LHYASLSFQGLRLWEPADQEAPSTTEYSEIKI 673
+ YASLSF R P +QEA EYSEI I
Sbjct: 563 IQYASLSFHKARPQYPQEQEAIG-YEYSEINI 593
>gi|193794819 sialic acid binding Ig-like lectin 6 isoform 2
precursor [Homo sapiens]
Length = 437
Score = 225 bits (574), Expect = 9e-59
Identities = 138/342 (40%), Positives = 188/342 (54%), Gaps = 28/342 (8%)
Query: 15 LLPLLLPVLGAGSLNKDPSYSLQVQRQVPVPEGLCVIVSCNLSYPRDGWDESTAAYGYWF 74
+LPLLLP+L AG+L ++ + L+ + V EGLCV+V C L S YGYWF
Sbjct: 12 MLPLLLPLLWAGALAQERRFQLEGPESLTVQEGLCVLVPCRLPTTLPA---SYYGYGYWF 68
Query: 75 KGRTSPKTGAPVATNNQSREVEMSTRDRFQLTGDPGKGSCSLVIRDAQREDEAWYFFRVE 134
PVATN+ EV+ TR RF L DP + +CSL IRDA+R D A YFFR+
Sbjct: 69 LEGAD----VPVATNDPDEEVQEETRGRFHLLWDPRRKNCSLSIRDARRRDNAAYFFRL- 123
Query: 135 RGSRVRHSFLSNAFFLKVTALTKKPDVYIPETLEPGQPVTVICVFNWAFKKCPAPSFSWT 194
+ +++ + S+ ++V ALT +P++ IP TLE G P + C W ++ P FSW
Sbjct: 124 KSKWMKYGYTSSKLSVRVMALTHRPNISIPGTLESGHPSNLTCSVPWVCEQGTPPIFSWM 183
Query: 195 GAALSPRRTRPSTSHFSVLSFTPSPQDHDTDLTCHVDFSRKGVSAQRTVRLRVAYAPKDL 254
AA P P T+ SVL+ TP PQDH T+LTC V F GV+ +RT++L
Sbjct: 184 SAA--PTSLGPRTTQSSVLTITPRPQDHSTNLTCQVTFPGAGVTMERTIQL--------- 232
Query: 255 IISISHDNTSALELQGNVIYLEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGP 314
N S+ ++ N L V +GQ LRLLC AD PPA LSW L+++
Sbjct: 233 -------NVSSFKILQNTSSLPVLEGQALRLLCDADGNPPAHLSWFQGFPALNATPI--S 283
Query: 315 RTLGLELRGVRAGDSGRYTCRAENRLGSQQQALDLSVQYPPE 356
T LEL V + + G +TCRA++ LGS Q +L L V + PE
Sbjct: 284 NTGVLELPQVGSAEEGDFTCRAQHPLGSLQISLSLFVHWKPE 325
Score = 96.3 bits (238), Expect = 9e-20
Identities = 48/95 (50%), Positives = 63/95 (66%)
Query: 364 QANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPPARLSWTRWGQTVGPSQPSDPGVLEL 423
Q N + + L N +SLPVLEGQ+LRL+C +PPA LSW + + + S+ GVLEL
Sbjct: 231 QLNVSSFKILQNTSSLPVLEGQALRLLCDADGNPPAHLSWFQGFPALNATPISNTGVLEL 290
Query: 424 PPIQMEHEGEFTCHAQHPLGSQHVSLSLSVHYPPQ 458
P + EG+FTC AQHPLGS +SLSL VH+ P+
Sbjct: 291 PQVGSAEEGDFTCRAQHPLGSLQISLSLFVHWKPE 325
Score = 94.4 bits (233), Expect = 3e-19
Identities = 104/376 (27%), Positives = 142/376 (37%), Gaps = 49/376 (13%)
Query: 312 WGPR--TLGLELRGVRAGDSGRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTV 369
W PR L +R R D+ Y R +++ + Y L V V
Sbjct: 97 WDPRRKNCSLSIRDARRRDNAAYFFRLKSKW--------MKYGYTSSKLSVRVM-----A 143
Query: 370 LENLGNGTSLPVLE-GQSLRLVC----VTHSSPPARLSWTRWGQTVGPSQPSDPGVLELP 424
L + N + LE G L C V P SW T + + VL +
Sbjct: 144 LTHRPNISIPGTLESGHPSNLTCSVPWVCEQGTPPIFSWMSAAPTSLGPRTTQSSVLTIT 203
Query: 425 PIQMEHEGEFTCHAQHPLGS----QHVSLSLSVHYPPQLLGPSCSWEAEGLHCSCSSQAS 480
P +H TC P + + L++S Q E + L C + +
Sbjct: 204 PRPQDHSTNLTCQVTFPGAGVTMERTIQLNVSSFKILQNTSSLPVLEGQALRLLCDADGN 263
Query: 481 PAPSLRWWLGEELLEGN--SSQGSFEVTPSSAGPWANSSLSLHGGLSSGLRLRCKAWNVH 538
P L W+ G L S+ G E L G G C+A +
Sbjct: 264 PPAHLSWFQGFPALNATPISNTGVLE-------------LPQVGSAEEG-DFTCRAQHPL 309
Query: 539 GAQSGSVFQLLPGKLEHGGGLGLGAALGAGVAALLAFCSCLVVFRVKICRKEARKRAAAE 598
G+ S+ + K E G LGA GA + L+ C C + FRVK RK+A +
Sbjct: 310 GSLQISLSLFVHWKPEGRAGGVLGAVWGASITTLVFLCVCFI-FRVKTRRKKAAQPVQNT 368
Query: 599 QDVPSTLGPISQGHQHECSAGSSQDHPPPGAATYTPGKGEEQELHYASLSFQGLRLWEPA 658
DV + S+GHQH+ G DHP A P +EQELHYA L F ++ EP
Sbjct: 369 DDVNPVMVSGSRGHQHQFQTGIVSDHP----AEAGPISEDEQELHYAVLHFHKVQPQEP- 423
Query: 659 DQEAPSTTEYSEIKIH 674
+ TEYSEIKIH
Sbjct: 424 ---KVTDTEYSEIKIH 436
>gi|130979981 CD33 antigen isoform 1 precursor [Homo sapiens]
Length = 364
Score = 214 bits (546), Expect = 2e-55
Identities = 114/260 (43%), Positives = 158/260 (60%), Gaps = 4/260 (1%)
Query: 16 LPLLLPVLGAGSLNKDPSYSLQVQRQVPVPEGLCVIVSCNLSYPRDGWDESTAAYGYWFK 75
L LLLP+L AG+L DP++ LQVQ V V EGLCV+V C +P +D+++ +GYWF+
Sbjct: 3 LLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFR 62
Query: 76 GRTSPKTGAPVATNNQSREVEMSTRDRFQLTGDPGKGSCSLVIRDAQREDEAWYFFRVER 135
+PVATN +EV+ T+ RF+L GDP + +CSL I DA+R D YFFR+ER
Sbjct: 63 EGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMER 122
Query: 136 GSRVRHSFLSNAFFLKVTALTKKPDVYIPETLEPGQPVTVICVFNWAFKKCPAPSFSWTG 195
GS ++S+ S + VT LT +P + IP TLEPG + C +WA ++ P FSW
Sbjct: 123 GS-TKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLS 181
Query: 196 AALSPRRTRPSTSHFSVLSFTPSPQDHDTDLTCHVDFSRKGVSAQRTVRLRVAYAPKDLI 255
AA P P T+H SVL TP PQDH T+LTC V F+ GV+ +RT++L V Y P++
Sbjct: 182 AA--PTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPT 239
Query: 256 ISI-SHDNTSALELQGNVIY 274
I D + E + V++
Sbjct: 240 TGIFPGDGSGKQETRAGVVH 259
Score = 73.2 bits (178), Expect = 8e-13
Identities = 48/123 (39%), Positives = 65/123 (52%), Gaps = 10/123 (8%)
Query: 551 GKLEHGGGLGLGAALGAGVAALLAFCSCLVVFRVKICRKEARKRAAAEQDVPSTLGPISQ 610
GK E G+ GA GAGV ALLA C CL+ F VK R++A + A D T G S
Sbjct: 249 GKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASP 308
Query: 611 GHQHECSA-GSSQDHPPPGAATYTPGKGEEQELHYASLSFQGLRLWEPADQEAPSTTEYS 669
HQ + G ++ GAA P ++ELHYASL+F G+ + ++TEYS
Sbjct: 309 KHQKKSKLHGPTETSSCSGAA---PTVEMDEELHYASLNFHGM------NPSKDTSTEYS 359
Query: 670 EIK 672
E++
Sbjct: 360 EVR 362
>gi|11225258 myelin associated glycoprotein isoform a precursor
[Homo sapiens]
Length = 626
Score = 171 bits (432), Expect = 3e-42
Identities = 143/510 (28%), Positives = 226/510 (44%), Gaps = 58/510 (11%)
Query: 46 EGLCVIVSCNLSYPRDGWDESTAA--YGYWFKGRTSPKTGAPVATNNQSREVEMSTRDRF 103
EG CV + C +P DE A +G W+ PK PV ++++ V S + R
Sbjct: 34 EGTCVSIPCRFDFP----DELRPAVVHGVWYFNSPYPKNYPPVVFKSRTQVVHESFQGRS 89
Query: 104 QLTGDPGKGSCSLVIRDAQREDEAWYFFRVERGSRVRHSFLSNAFFLKVTALTKKPDVYI 163
+L GD G +C+L++ + E Y+FR + G +++F ++ V + P++ +
Sbjct: 90 RLLGDLGLRNCTLLLSNVSPELGGKYYFRGDLGGYNQYTFSEHS----VLDIVNTPNIVV 145
Query: 164 PETLEPGQPVTVICVFNWAFKKCP--APSFSWTG-------AALSPRRTRPST-SHFSVL 213
P + G V V C+ CP P SW G A L R T S+L
Sbjct: 146 PPEVVAGTEVEVSCMVP---DNCPELRPELSWLGHEGLGEPAVLGRLREDEGTWVQVSLL 202
Query: 214 SFTPSPQDHDTDLTCHVDFSRKGVSAQRTVRLRVAYAPKDLIISISHDNTSALELQGNVI 273
F P+ + + L C F + + + V Y P +I + + A+E
Sbjct: 203 HFVPTREANGHRLGCQASFPNTTLQFEGYASMDVKYPP---VIVEMNSSVEAIE------ 253
Query: 274 YLEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLGLELRGVRAGDSGRYT 333
G + LLC ADS PP L+W+ VL + +L LEL V + G Y
Sbjct: 254 ------GSHVSLLCGADSNPPPLLTWMRDGTVLREA---VAESLLLELEEVTPAEDGVYA 304
Query: 334 CRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVT 393
C AEN G + + LSV Y P V NGT + V EG+++ ++C T
Sbjct: 305 CLAENAYGQDNRTVGLSVMYAPWKPTV--------------NGTMVAV-EGETVSILCST 349
Query: 394 HSSPPARLSWTRWGQTVGPSQPSDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSV 453
S+P L+ + Q + LELP + E +GE+ C A++ G + + +LSV
Sbjct: 350 QSNPDPILTIFKEKQILSTVIYESELQLELPAVSPEDDGEYWCVAENQYGQRATAFNLSV 409
Query: 454 HYPPQLLGPS-CSWEAEGLHCSCSSQASPAPSLRWWLGEELLEGNSSQGSFEVTPSSAGP 512
+ P LL S C+ + + C C +++P PS+ + L + N S+ F V +G
Sbjct: 410 EFAPVLLLESHCAAARDTVQCLCVVKSNPEPSVAFELPSRNVTVNESEREF-VYSERSGL 468
Query: 513 WANSSLSLHGGLSSGLRLRCKAWNVHGAQS 542
S L+L G + R+ C A N++GA+S
Sbjct: 469 VLTSILTLRGQAQAPPRVICTARNLYGAKS 498
>gi|18104957 myelin associated glycoprotein isoform b precursor
[Homo sapiens]
Length = 582
Score = 171 bits (432), Expect = 3e-42
Identities = 143/510 (28%), Positives = 226/510 (44%), Gaps = 58/510 (11%)
Query: 46 EGLCVIVSCNLSYPRDGWDESTAA--YGYWFKGRTSPKTGAPVATNNQSREVEMSTRDRF 103
EG CV + C +P DE A +G W+ PK PV ++++ V S + R
Sbjct: 34 EGTCVSIPCRFDFP----DELRPAVVHGVWYFNSPYPKNYPPVVFKSRTQVVHESFQGRS 89
Query: 104 QLTGDPGKGSCSLVIRDAQREDEAWYFFRVERGSRVRHSFLSNAFFLKVTALTKKPDVYI 163
+L GD G +C+L++ + E Y+FR + G +++F ++ V + P++ +
Sbjct: 90 RLLGDLGLRNCTLLLSNVSPELGGKYYFRGDLGGYNQYTFSEHS----VLDIVNTPNIVV 145
Query: 164 PETLEPGQPVTVICVFNWAFKKCP--APSFSWTG-------AALSPRRTRPST-SHFSVL 213
P + G V V C+ CP P SW G A L R T S+L
Sbjct: 146 PPEVVAGTEVEVSCMVP---DNCPELRPELSWLGHEGLGEPAVLGRLREDEGTWVQVSLL 202
Query: 214 SFTPSPQDHDTDLTCHVDFSRKGVSAQRTVRLRVAYAPKDLIISISHDNTSALELQGNVI 273
F P+ + + L C F + + + V Y P +I + + A+E
Sbjct: 203 HFVPTREANGHRLGCQASFPNTTLQFEGYASMDVKYPP---VIVEMNSSVEAIE------ 253
Query: 274 YLEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLGLELRGVRAGDSGRYT 333
G + LLC ADS PP L+W+ VL + +L LEL V + G Y
Sbjct: 254 ------GSHVSLLCGADSNPPPLLTWMRDGTVLREA---VAESLLLELEEVTPAEDGVYA 304
Query: 334 CRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVT 393
C AEN G + + LSV Y P V NGT + V EG+++ ++C T
Sbjct: 305 CLAENAYGQDNRTVGLSVMYAPWKPTV--------------NGTMVAV-EGETVSILCST 349
Query: 394 HSSPPARLSWTRWGQTVGPSQPSDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSV 453
S+P L+ + Q + LELP + E +GE+ C A++ G + + +LSV
Sbjct: 350 QSNPDPILTIFKEKQILSTVIYESELQLELPAVSPEDDGEYWCVAENQYGQRATAFNLSV 409
Query: 454 HYPPQLLGPS-CSWEAEGLHCSCSSQASPAPSLRWWLGEELLEGNSSQGSFEVTPSSAGP 512
+ P LL S C+ + + C C +++P PS+ + L + N S+ F V +G
Sbjct: 410 EFAPVLLLESHCAAARDTVQCLCVVKSNPEPSVAFELPSRNVTVNESEREF-VYSERSGL 468
Query: 513 WANSSLSLHGGLSSGLRLRCKAWNVHGAQS 542
S L+L G + R+ C A N++GA+S
Sbjct: 469 VLTSILTLRGQAQAPPRVICTARNLYGAKS 498
>gi|118197279 sialic acid binding Ig-like lectin 7 isoform 2 [Homo
sapiens]
Length = 374
Score = 132 bits (331), Expect = 1e-30
Identities = 79/162 (48%), Positives = 99/162 (61%), Gaps = 7/162 (4%)
Query: 298 SWVLQDRVLSSSHPWG-PRTLG--LELRGVRAGDSGRYTCRAEN---RLGSQQQALDLSV 351
+W +Q+ H G P+T L +R R D+GRY R E + + L ++V
Sbjct: 84 AWAVQEETRDRFHLLGDPQTKNCTLSIRDARMSDAGRYFFRMEKGNIKWNYKYDQLSVNV 143
Query: 352 QYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPPARLSWTRWGQTVG 411
PP+NL V V Q T LGN +SL VLEGQSLRLVC S+PPARLSWT T+
Sbjct: 144 TDPPQNLTVTVFQGEGTASTALGNSSSLSVLEGQSLRLVCAVDSNPPARLSWTWRSLTLY 203
Query: 412 PSQPSDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSV 453
PSQPS+P VLEL + + EGEFTC AQ+ LGSQHVSL+LS+
Sbjct: 204 PSQPSNPLVLEL-QVHLGDEGEFTCRAQNSLGSQHVSLNLSL 244
Score = 112 bits (281), Expect = 9e-25
Identities = 73/213 (34%), Positives = 108/213 (50%), Gaps = 25/213 (11%)
Query: 14 LLLPLLLPVLGA-----GSLNKDPSYSLQVQRQVPVPEGLCVIVSCNLSYPRDGWDESTA 68
+LL LLLP+L G + YSL +Q V V EG+CV V C+ SYP D +S
Sbjct: 1 MLLLLLLPLLWGRERVEGQKSNRKDYSLTMQSSVTVQEGMCVHVRCSFSYPVDSQTDSDP 60
Query: 69 AYGYWFKGRTSPKTGAPVATNNQSREVEMSTRDRFQLTGDPGKGSCSLVIRDAQREDEAW 128
+GYWF+ APVATNN + V+ TRDRF L GDP +C+L IRDA+ D
Sbjct: 61 VHGYWFRAGNDISWKAPVATNNPAWAVQEETRDRFHLLGDPQTKNCTLSIRDARMSDAGR 120
Query: 129 YFFRVERGSRVRHSFLSNAFFLKVTALTKKPDVYIPE---------------TLEPGQPV 173
YFFR+E+G+ ++ ++ + + VT + V + + ++ GQ +
Sbjct: 121 YFFRMEKGN-IKWNYKYDQLSVNVTDPPQNLTVTVFQGEGTASTALGNSSSLSVLEGQSL 179
Query: 174 TVICVFNWAFKKCPAPSFSWTGAALSPRRTRPS 206
++C A P SWT +L+ ++PS
Sbjct: 180 RLVC----AVDSNPPARLSWTWRSLTLYPSQPS 208
Score = 83.6 bits (205), Expect = 6e-16
Identities = 46/108 (42%), Positives = 62/108 (57%), Gaps = 3/108 (2%)
Query: 245 LRVAYAPKDLIISISHDNTSALELQGNVIYLEVQKGQFLRLLCAADSQPPATLSWVLQDR 304
+ V P++L +++ +A GN L V +GQ LRL+CA DS PPA LSW +
Sbjct: 141 VNVTDPPQNLTVTVFQGEGTASTALGNSSSLSVLEGQSLRLVCAVDSNPPARLSWTWRSL 200
Query: 305 VLSSSHPWGPRTLGLELRGVRAGDSGRYTCRAENRLGSQQQALDLSVQ 352
L S P P L L+ V GD G +TCRA+N LGSQ +L+LS+Q
Sbjct: 201 TLYPSQPSNPLVLELQ---VHLGDEGEFTCRAQNSLGSQHVSLNLSLQ 245
Score = 69.3 bits (168), Expect = 1e-11
Identities = 66/216 (30%), Positives = 97/216 (44%), Gaps = 27/216 (12%)
Query: 467 EAEGLHCSCSSQASPAPSLRWWLGEELLEGNSSQGSFEVTPSSAGPWANSSLSLHGGLSS 526
E + L C+ ++P L W + S + PS L +H G
Sbjct: 175 EGQSLRLVCAVDSNPPARLSW-----------TWRSLTLYPSQPSNPLVLELQVHLGDEG 223
Query: 527 GLRLRCKAWNVHGAQ----SGSVFQLLPGKLEHGGGLGLGAALGAGVAALLAFCSCLVVF 582
C+A N G+Q + S+ Q GK+ G+ LGA GAG AL+ C++
Sbjct: 224 --EFTCRAQNSLGSQHVSLNLSLQQEYTGKMRPVSGVLLGAVGGAGATALVFLSFCVIFI 281
Query: 583 RVKICRKEARKRAA-----AEQDVPSTLGPISQGHQHECSAGSSQDHPPPGAATYTPGKG 637
V+ CRK++ + AA +D + G SQG+ E A + H G A ++ G
Sbjct: 282 VVRSCRKKSARPAADVGDIGMKDANTIRGSASQGNLTESWADDNPRH--HGLAAHS--SG 337
Query: 638 EEQELHYASLSFQGLRLWEPADQEAPSTTEYSEIKI 673
EE+E+ YA LSF + + QEA + EYSEIKI
Sbjct: 338 EEREIQYAPLSFHKGEPQDLSGQEA-TNNEYSEIKI 372
>gi|13489095 sialoadhesin precursor [Homo sapiens]
Length = 1709
Score = 108 bits (269), Expect = 2e-23
Identities = 135/531 (25%), Positives = 217/531 (40%), Gaps = 80/531 (15%)
Query: 11 PEMLLLPLLLPVLGAGSLNKDPSYSLQVQRQVPVPEGLCVIVSCNLSYPRDGW--DESTA 68
P++LLL P A S+ + + V +G C+++ C S+P D D TA
Sbjct: 5 PKLLLLASFFPAGQA-------SWGVSSPQDVQGVKGSCLLIPCIFSFPADVEVPDGITA 57
Query: 69 AYGYWFKGRTSPKTGAPVATNNQSREVEMSTRDRFQLTGDPGKGSCSLVIRDAQREDEAW 128
+ Y + G+ V+ + + VE R R + G+P C+L+++D Q ED
Sbjct: 58 IWYYDYSGQRQV-----VSHSADPKLVEARFRGRTEFMGNPEHRVCNLLLKDLQPEDSGS 112
Query: 129 YFFRVERGSRVRHSFLSNAFFLKVTALTKKPDVYIPETLEPGQPVTVICV---------- 178
Y FR E R S + + VT + P + P L G V C
Sbjct: 113 YNFRFEISEVNRWSDVKGT-LVTVTEEPRVPTIASPVELLEGTEVDFNCSTPYVCLQEQV 171
Query: 179 -FNWAFKKCPAPSFSWTGAALSPRRTRPSTSHFSVLSFTPSPQDHDTDLTCHVDFSRKGV 237
W + PA S ++ P H L S QDH L C + +
Sbjct: 172 RLQWQGQD-PARSVTFNSQKFEP----TGVGHLETLHMAMSWQDHGRILRCQLSVANH-- 224
Query: 238 SAQRTVRLRVAYAPKDLIISISHDNTSALELQGNVIYLEVQKGQFLRLLCAADSQPPA-- 295
AQ + L+V YAPK + I +S + L G+ + L C +S PA
Sbjct: 225 RAQSEIHLQVKYAPKGVKILLSPSGRNIL------------PGELVTLTCQVNSSYPAVS 272
Query: 296 TLSWVLQDRVLSSSHPWGPRTLGLELRGVRAGDSGRYTCRAENRLGSQQQALDLSVQYPP 355
++ W L+D V + +T L L D+G YTC+AEN +G S+ PP
Sbjct: 273 SIKW-LKDGVRLQT-----KTGVLHLPQAAWSDAGVYTCQAENGVG--------SLVSPP 318
Query: 356 ENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPPARLSWTRWGQTVGPSQP 415
+L + +++ + + P+LE Q++ LVC T + P+ L ++ W + +
Sbjct: 319 ISLHIFMAEVQVS--------PAGPILENQTVTLVCNTPNEAPSDLRYS-WYKNHVLLED 369
Query: 416 SDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVS-LSLSVHYPPQLLGPSCSWEAEG---- 470
+ L L G + C Q+ GS+ +S+ V++PP + E +
Sbjct: 370 AHSHTLRLHLATRADTGFYFCEVQNVHGSERSGPVSVVVNHPPLTPVLTAFLETQAGLVG 429
Query: 471 -LHCSCSSQASPAPSLRWWLGEELLEGNSSQGSFEVTPSSAGPWANSSLSL 520
LHCS S+ P +L G +L S+ G + +P +G +SL L
Sbjct: 430 ILHCSVVSE--PLATLVLSHGGHILA--STSGDSDHSPRFSGTSGPNSLRL 476
Score = 70.1 bits (170), Expect = 7e-12
Identities = 66/238 (27%), Positives = 99/238 (41%), Gaps = 38/238 (15%)
Query: 224 TDLTCHVDFSRKGVSAQRTVRLRVAYAPKDLIISISHDNTSALELQGNVIYLEVQKGQFL 283
T C V + R + L V YAP++L ++ LE GQ
Sbjct: 1145 TSYRCGVGPPGRAPRLSRPITLDVLYAPRNLRLTY---------------LLESHGGQLA 1189
Query: 284 RLLCAADSQPPATLSWVLQDRVLSSSHPWG-PRTLGLELRGVRAGDSGRYTCRAENRLGS 342
+LC DS+PPA L+ R+L+SS P TL LELRG + D G Y+C A + LG
Sbjct: 1190 LVLCTVDSRPPAQLALSHAGRLLASSTAASVPNTLRLELRGPQPRDEGFYSCSARSPLGQ 1249
Query: 343 QQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSS-PPARL 401
+L+L + E +RV+++ V EG + + C ++ P
Sbjct: 1250 ANTSLELRL----EGVRVILA-------------PEAAVPEGAPITVTCADPAAHAPTLY 1292
Query: 402 SWTRWGQTVGPSQPSDPGVLELPPIQMEHEGEFTCHAQHPLGSQHV-SLSLSVHYPPQ 458
+W G+ + Q L H G ++C AQ G++ +L V Y PQ
Sbjct: 1293 TWYHNGRWL---QEGPAASLSFLVATRAHAGAYSCQAQDAQGTRSSRPAALQVLYAPQ 1347
Score = 68.6 bits (166), Expect = 2e-11
Identities = 111/480 (23%), Positives = 181/480 (37%), Gaps = 81/480 (16%)
Query: 96 EMSTRDRFQLTGDPGKGSCSLVIRDAQREDEAWYFFRVERGSRVRHSFLSNAFFLKVTAL 155
++ + RFQ + S L +R+ D Y R E + + S S F ++ +
Sbjct: 843 QVPSHGRFQAKAEAN--SLKLEVRELGLGDSGSY--RCEATNVLGSSNTSLFFQVRGAWV 898
Query: 156 TKKPDVYIPETLEPGQPVTVICVFNWAFKKCPAPSFSWTGAALSPRRTRPSTSHFSVLSF 215
P PE L+ GQ V + C + + S+ W + + +T F+ ++
Sbjct: 899 QVSPS---PE-LQEGQAVVLSCQVHTGVPE--GTSYRWYRDGQPLQESTSATLRFAAITL 952
Query: 216 TPSPQDHDTDLTCHVDFSRKGV-SAQRTVRLRVAYAPKDLIISISHDNTSALELQGNVIY 274
T + H C S + L V+YAP+ + ++
Sbjct: 953 TQAGAYH-----CQAQAPGSATTSLAAPISLHVSYAPRHVTLTT---------------L 992
Query: 275 LEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSS-----HPWG----------PRTLGL 319
++ G+ LLC DS PPA L + DR+++S+ P G P TL L
Sbjct: 993 MDTGPGRLGLLLCRVDSDPPAQLRLLHGDRLVASTLQGVGGPEGSSPRLHVAVAPNTLRL 1052
Query: 320 ELRGVRAGDSGRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSL 379
E+ G D G Y C A N LG + D Q N+
Sbjct: 1053 EIHGAMLEDEGVYICEASNTLGQASASADFDAQ-----------------AVNVQVWPGA 1095
Query: 380 PVLEGQSLRLVCVTHSSPPARLSWTRWGQTVGPSQPSDPGVLELPPIQMEHEGEFTCHAQ 439
V EGQ + L C+ ++ PA+L++T W Q Q D + LP + + + C
Sbjct: 1096 TVREGQLVNLTCLVWTTHPAQLTYT-WYQ--DGQQRLDAHSIPLPNVTVRDATSYRCGVG 1152
Query: 440 HPLGSQHVS--LSLSVHYPPQLLGPSCSWEAEGLHCS---CSSQASPAPSLRWWLGEELL 494
P + +S ++L V Y P+ L + E+ G + C+ + P L LL
Sbjct: 1153 PPGRAPRLSRPITLDVLYAPRNLRLTYLLESHGGQLALVLCTVDSRPPAQLALSHAGRLL 1212
Query: 495 EGNSSQGSFEVT---------PSSAGPWANSSLSLHGGLSSGLRLRCKAWNVHGAQSGSV 545
+S+ S T P G ++ S+ S G ++ L LR + V A +V
Sbjct: 1213 -ASSTAASVPNTLRLELRGPQPRDEGFYSCSARSPLGQANTSLELRLEGVRVILAPEAAV 1271
Score = 67.0 bits (162), Expect = 6e-11
Identities = 106/409 (25%), Positives = 153/409 (37%), Gaps = 75/409 (18%)
Query: 116 LVIRDAQREDEAWYFFRVERGSRVRHSFLSNAFFLKVTALTKKPDVYIPETLEPGQPVTV 175
L +R Q DE F+ S + + S L+ + P+ +PE G P+TV
Sbjct: 1226 LELRGPQPRDEG--FYSCSARSPLGQANTSLELRLEGVRVILAPEAAVPE----GAPITV 1279
Query: 176 ICVFNWAFKKCPAPS-FSW--TGAALSPRRTRPSTSHFSVLSFTPSPQDHDTDLTCHVDF 232
C A AP+ ++W G L + P+ S LSF + + H +C
Sbjct: 1280 TC----ADPAAHAPTLYTWYHNGRWL---QEGPAAS----LSFLVATRAHAGAYSCQAQ- 1327
Query: 233 SRKGVSAQRTVRLRVAYAPKDLIISISHDNTSALELQGNVIYLEVQKGQFLRLLCAADSQ 292
+G + R L+V YAP+D ++S D+ + + C DS+
Sbjct: 1328 DAQGTRSSRPAALQVLYAPQDAVLSSFRDSRAR---------------SMAVIQCTVDSE 1372
Query: 293 PPATLSWVLQDRVLSSS---HPWGPRT---------LGLELRGVRAGDSGRYTCRAENRL 340
PPA L+ +VL++S H T L L+++ V AGD Y C A+N L
Sbjct: 1373 PPAELALSHDGKVLATSSGVHSLASGTGHVQVARNALRLQVQDVPAGDD-TYVCTAQNLL 1431
Query: 341 GSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSP-PA 399
GS L V E RV+ L V EG +L L C P P
Sbjct: 1432 GSISTIGRLQV----EGARVVAE-------------PGLDVPEGAALNLSCRLLGGPGPV 1474
Query: 400 RLSWTRWGQTVGPSQPSDPGVLELPPIQMEHEGEFTCHAQHPLG-SQHVSLSLSVHYPPQ 458
S W L + G + C A+ P G + + L V YPP+
Sbjct: 1475 GNSTFAWFWNDRRLHAEPVPTLAFTHVARAQAGMYHCLAELPTGAAASAPVMLRVLYPPK 1534
Query: 459 LLGPSCSWEAEG-----LHCSCSSQASPAPSLRWWLGEELLEGNSSQGS 502
E EG L C S+ P SL LG L+ + QG+
Sbjct: 1535 TPTMMVFVEPEGGLRGILDCRVDSE--PLASLTLHLGSRLVASSQPQGA 1581
Score = 65.5 bits (158), Expect = 2e-10
Identities = 126/517 (24%), Positives = 181/517 (35%), Gaps = 109/517 (21%)
Query: 104 QLTGDPGKGSCSLVIRDAQREDEAWYFFRVERGSRVRHSFLSNAFFLKVTALTKKPDVYI 163
+ +G G S L IRD + D Y + + + ++ + F L P +
Sbjct: 464 RFSGTSGPNSLRLEIRDLEETDSGEY--KCSATNSLGNATSTLDFHANAARLLISPAAEV 521
Query: 164 PETLEPGQPVTVICVFNWAFKKCPAPSFSW--TGAALSPRRTRPSTSHFSVLSFTPSPQD 221
E GQ VT+ C P FSW GA L H S P
Sbjct: 522 VE----GQAVTLSC--RSGLSPTPDARFSWYLNGALL----------HEGPGSSLLLPAA 565
Query: 222 HDTDLTCHVDFSRKGVSAQ---RTVRLRVAYAPKDLIISISHDNTSALELQGNVIYLEVQ 278
TD + +R G SA L V Y P+ + D +A
Sbjct: 566 SSTDAGSYHCRARDGHSASGPSSPAVLTVLYPPRQPTFTTRLDLDAA----------GAG 615
Query: 279 KGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWG------------------PRTLGLE 320
G+ LLC DS PPA L + +DRV+++S P G P L +E
Sbjct: 616 AGRRGLLLCRVDSDPPARLQLLHKDRVVATSLPSGGGCSTCGGCSPRMKVTKAPNLLRVE 675
Query: 321 LRGVRAGDSGRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLP 380
+ + G Y C A N LG+ + + Q TVL + T
Sbjct: 676 IHNPLLEEEGLYLCEASNALGNASTSATFNGQ--------------ATVLAIAPSHT--- 718
Query: 381 VLEGQSLRLVCVTH---SSPPARLSWTR----WGQTVGPSQPSDPGVLELPPIQMEHEGE 433
+ EG L C + PA SW R W Q GP + + L P+
Sbjct: 719 LQEGTEANLTCNVSREAAGSPANFSWFRNGVLWAQ--GPLE-----TVTLLPVARTDAAL 771
Query: 434 FTCHAQHPLGSQ-HVSLSLSVHYPPQLLGPSCSWEAEGLHCS---CSSQASPAPSLRWWL 489
+ C G+Q + LSV YPP S + H + C+ + P L +
Sbjct: 772 YACRILTEAGAQLSTPVLLSVLYPPDRPKLSALLDMGQGHMALFICTVDSRPLALLALFH 831
Query: 490 GEELLEGN-----SSQGSFEVTPSSAGPWANSSLSLHG---GLSSGLRLRCKAWNVHGAQ 541
GE LL + S G F+ + +SL L GL RC+A NV G+
Sbjct: 832 GEHLLATSLGPQVPSHGRFQAKAEA------NSLKLEVRELGLGDSGSYRCEATNVLGSS 885
Query: 542 SGSVFQLLPG---------KLEHGGGLGLGAALGAGV 569
+ S+F + G +L+ G + L + GV
Sbjct: 886 NTSLFFQVRGAWVQVSPSPELQEGQAVVLSCQVHTGV 922
Score = 61.6 bits (148), Expect = 2e-09
Identities = 60/200 (30%), Positives = 82/200 (41%), Gaps = 35/200 (17%)
Query: 274 YLEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSS-----------SHPWGPRTLGLELR 322
+LE Q G L C+ S+P ATL +L+S S GP +L LE+R
Sbjct: 420 FLETQAGLVGILHCSVVSEPLATLVLSHGGHILASTSGDSDHSPRFSGTSGPNSLRLEIR 479
Query: 323 GVRAGDSGRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVL 382
+ DSG Y C A N LG+ LD + R+++S A V+
Sbjct: 480 DLEETDSGEYKCSATNSLGNATSTLD----FHANAARLLISPA-------------AEVV 522
Query: 383 EGQSLRLVCVTHSS--PPARLSWTRWGQTVGPSQPSDPGVLELPPIQMEHEGEFTCHAQ- 439
EGQ++ L C + S P AR SW G + S L LP G + C A+
Sbjct: 523 EGQAVTLSCRSGLSPTPDARFSWYLNGALLHEGPGSS---LLLPAASSTDAGSYHCRARD 579
Query: 440 -HPLGSQHVSLSLSVHYPPQ 458
H L+V YPP+
Sbjct: 580 GHSASGPSSPAVLTVLYPPR 599
Score = 50.1 bits (118), Expect = 7e-06
Identities = 36/119 (30%), Positives = 53/119 (44%), Gaps = 27/119 (22%)
Query: 236 GVSAQRTVRLRVAYAPKDLIISISHDNTSALELQGNVIYLEVQKGQFLRLLCAADSQPPA 295
G +A V LRV Y PK + ++++E + G L C DS+P A
Sbjct: 1518 GAAASAPVMLRVLYPPKTPTM---------------MVFVEPEGGLRGILDCRVDSEPLA 1562
Query: 296 TLSWVLQDRVLSSSHPWG------------PRTLGLELRGVRAGDSGRYTCRAENRLGS 342
+L+ L R+++SS P G P L +++ +R D G Y C A N LGS
Sbjct: 1563 SLTLHLGSRLVASSQPQGAPAEPHIHVLASPNALRVDIEALRPSDQGEYICSASNVLGS 1621
Score = 38.1 bits (87), Expect = 0.028
Identities = 50/198 (25%), Positives = 71/198 (35%), Gaps = 39/198 (19%)
Query: 275 LEVQKGQFLRLLCAADSQPP----ATLSWVLQDRVLSSSHPWGPRTLGLELRGVRAGDSG 330
L+V +G L L C P +T +W DR L + L V +G
Sbjct: 1453 LDVPEGAALNLSCRLLGGPGPVGNSTFAWFWNDRRLHAEP-----VPTLAFTHVARAQAG 1507
Query: 331 RYTCRAENRLGSQQQA-LDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRL 389
Y C AE G+ A + L V YPP+ +MV L + L
Sbjct: 1508 MYHCLAELPTGAAASAPVMLRVLYPPKTPTMMVFVEPEGGLRGI---------------L 1552
Query: 390 VCVTHSSPPARLSWTRWGQTVGPSQP------------SDPGVL--ELPPIQMEHEGEFT 435
C S P A L+ + V SQP + P L ++ ++ +GE+
Sbjct: 1553 DCRVDSEPLASLTLHLGSRLVASSQPQGAPAEPHIHVLASPNALRVDIEALRPSDQGEYI 1612
Query: 436 CHAQHPLGSQHVSLSLSV 453
C A + LGS S V
Sbjct: 1613 CSASNVLGSASTSTYFGV 1630
>gi|130980072 CD33 antigen isoform 2 precursor [Homo sapiens]
Length = 237
Score = 96.3 bits (238), Expect = 9e-20
Identities = 50/121 (41%), Positives = 69/121 (57%), Gaps = 3/121 (2%)
Query: 155 LTKKPDVYIPETLEPGQPVTVICVFNWAFKKCPAPSFSWTGAALSPRRTRPSTSHFSVLS 214
LT +P + IP TLEPG + C +WA ++ P FSW AA P P T+H SVL
Sbjct: 14 LTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAA--PTSLGPRTTHSSVLI 71
Query: 215 FTPSPQDHDTDLTCHVDFSRKGVSAQRTVRLRVAYAPKDLIISI-SHDNTSALELQGNVI 273
TP PQDH T+LTC V F+ GV+ +RT++L V Y P++ I D + E + V+
Sbjct: 72 ITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVV 131
Query: 274 Y 274
+
Sbjct: 132 H 132
Score = 73.2 bits (178), Expect = 8e-13
Identities = 48/123 (39%), Positives = 65/123 (52%), Gaps = 10/123 (8%)
Query: 551 GKLEHGGGLGLGAALGAGVAALLAFCSCLVVFRVKICRKEARKRAAAEQDVPSTLGPISQ 610
GK E G+ GA GAGV ALLA C CL+ F VK R++A + A D T G S
Sbjct: 122 GKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASP 181
Query: 611 GHQHECSA-GSSQDHPPPGAATYTPGKGEEQELHYASLSFQGLRLWEPADQEAPSTTEYS 669
HQ + G ++ GAA P ++ELHYASL+F G+ + ++TEYS
Sbjct: 182 KHQKKSKLHGPTETSSCSGAA---PTVEMDEELHYASLNFHGM------NPSKDTSTEYS 232
Query: 670 EIK 672
E++
Sbjct: 233 EVR 235
>gi|157168355 CD22 molecule [Homo sapiens]
Length = 847
Score = 94.7 bits (234), Expect = 3e-19
Identities = 105/454 (23%), Positives = 175/454 (38%), Gaps = 61/454 (13%)
Query: 46 EGLCVIVSCNLSYPRDGWDESTAAYGYWFKGRTSPKTGAPVATNNQSREVEMSTRDRFQL 105
EG CV + C + + + TS G + + + +V S + R Q
Sbjct: 36 EGACVWIPCTYRALDGDLESFILFHNPEYNKNTSKFDGTRLYESTKDGKVP-SEQKRVQF 94
Query: 106 TGDPGKGSCSLVIRDAQREDEAWYFFRVERGSRVRHSFLSNAFFLKVTALTKKPDVYIPE 165
GD K +C+L I D R+E + L V+ P + +P
Sbjct: 95 LGDKNK-NCTLSIHPVHLNDSGQLGLRMESKTEK----WMERIHLNVSERPFPPHIQLPP 149
Query: 166 TLEPGQPVTVICVFNWAFKKCPAPSFSWT--------GAALSPRRTRPSTSHFSVLSFTP 217
++ Q VT+ C+ N++ P W A S T S S L F+P
Sbjct: 150 EIQESQEVTLTCLLNFSCYGYPI-QLQWLLEGVPMRQAAVTSTSLTIKSVFTRSELKFSP 208
Query: 218 SPQDHDTDLTCHVDFSRKGVSAQRTVRLRVAYAPKDLIISISHDNTSALELQGNVIYLEV 277
H +TC + + + TV+L V + PK LE++ V
Sbjct: 209 QWSHHGKIVTCQLQDADGKFLSNDTVQLNVKHTPK-------------LEIKVTPSDAIV 255
Query: 278 QKGQFLRLLCAADSQPP--ATLSWVLQDRVLSSSHPWGPRTLGLELRGVRAGDSGRYTCR 335
++G + + C S P T+SW+ L + T L LR V SG+Y C+
Sbjct: 256 REGDSVTMTCEVSSSNPEYTTVSWLKDGTSLKKQN-----TFTLNLREVTKDQSGKYCCQ 310
Query: 336 AENRLG-SQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTH 394
N +G + + + L VQY PE V + + P +EG + +C++
Sbjct: 311 VSNDVGPGRSEEVFLQVQYAPEPSTVQILHS--------------PAVEGSQVEFLCMSL 356
Query: 395 SSP-PARLSWTRWGQTVGPSQPSDPGVLELPPIQMEHEGEFTCHAQHPLGS--QHVSLSL 451
++P P +W G+ + Q + +P I H G ++C A++ LG+ + L
Sbjct: 357 ANPLPTNYTWYHNGKEM---QGRTEEKVHIPKILPWHAGTYSCVAENILGTGQRGPGAEL 413
Query: 452 SVHYPPQ-----LLGPSCSWEAEGLHCSCSSQAS 480
V YPP+ + P E + + SC+ +S
Sbjct: 414 DVQYPPKKVTTVIQNPMPIREGDTVTLSCNYNSS 447
Score = 70.5 bits (171), Expect = 5e-12
Identities = 58/224 (25%), Positives = 93/224 (41%), Gaps = 40/224 (17%)
Query: 243 VRLRVAYAPKDLIISISHDNTSALELQGNVIYLEVQKGQFLRLLCAADSQPPATLS--WV 300
V L V YAP+D+ + + E+ G + L C S P + W
Sbjct: 497 VALNVQYAPRDVRVRKIKPLS------------EIHSGNSVSLQCDFSSSHPKEVQFFWE 544
Query: 301 LQDRVLSSSHPWGPRTLGLELRGVRAGDSGRYTCRAENRLG-SQQQALDLSVQYPPENLR 359
R+L L + D+G Y+C N +G + +A L V Y P LR
Sbjct: 545 KNGRLLGKESQ-------LNFDSISPEDAGSYSCWVNNSIGQTASKAWTLEVLYAPRRLR 597
Query: 360 VMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPP-ARLSWTRWGQTVGPSQPSDP 418
V +S ++ V+EG+S L C + ++PP + +W W S P
Sbjct: 598 VSMSPGDQ-------------VMEGKSATLTCESDANPPVSHYTWFDWNNQ---SLPYHS 641
Query: 419 GVLELPPIQMEHEGEFTCHAQHPLGSQHVSLS-LSVHYPPQLLG 461
L L P++++H G + C + +G LS L+V+Y P+ +G
Sbjct: 642 QKLRLEPVKVQHSGAYWCQGTNSVGKGRSPLSTLTVYYSPETIG 685
Score = 42.7 bits (99), Expect = 0.001
Identities = 53/223 (23%), Positives = 91/223 (40%), Gaps = 32/223 (14%)
Query: 275 LEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLG-LELRGVRAGDSGRYT 333
+ +++G + L C +S P+ + + W +LG L+++ V D+
Sbjct: 430 MPIREGDTVTLSCNYNSSNPSVTRYEWKPH-----GAWEEPSLGVLKIQNV-GWDNTTIA 483
Query: 334 CRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVT 393
C A N S + L+VQY P ++RV + + + E + G S+ L C
Sbjct: 484 CAACNSWCSWASPVALNVQYAPRDVRV---RKIKPLSE---------IHSGNSVSLQCDF 531
Query: 394 HSSPPARLS--WTRWGQTVGPSQPSDPGVLELPPIQMEHEGEFTCHAQHPLG-SQHVSLS 450
SS P + W + G+ +G L I E G ++C + +G + + +
Sbjct: 532 SSSHPKEVQFFWEKNGRLLGKESQ-----LNFDSISPEDAGSYSCWVNNSIGQTASKAWT 586
Query: 451 LSVHYPPQLLGPSCS-----WEAEGLHCSCSSQASPAPSLRWW 488
L V Y P+ L S S E + +C S A+P S W
Sbjct: 587 LEVLYAPRRLRVSMSPGDQVMEGKSATLTCESDANPPVSHYTW 629
>gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 3874
Score = 92.4 bits (228), Expect = 1e-18
Identities = 88/326 (26%), Positives = 135/326 (41%), Gaps = 44/326 (13%)
Query: 169 PGQPVTVICVFNWAFKKCPAPSFSWTGAALSPRRTRPSTSHFSVLSFTPSP-QDHDTDLT 227
PG+ VT++C + P SW L ++ + H S + S Q D +
Sbjct: 2136 PGELVTMVC----PVRGSPPIHVSWLKDGLPLPLSQRTLLHGSGHTLRISKVQLADAGIF 2191
Query: 228 CHVDFSRKGVSAQRTVRLRVAYAPKDLIISISHDNTSALELQGNVIYLEVQKGQFLRLLC 287
V S GV A R L+V P +E Q +V+ V +G + L C
Sbjct: 2192 TCVAASPAGV-ADRNFTLQVQVPPV----------LEPVEFQNDVV---VVRGSLVELPC 2237
Query: 288 AADSQPPATLSWVLQ-DRVLSSSHPWGPRTLGLELRGVRAGDSGRYTCRAENRLGSQQQA 346
A P +SW+ + +LS S GP L+L V AGDSG Y+C A + G ++
Sbjct: 2238 EARGVPLPLVSWMKDGEPLLSQSLEQGP---SLQLEAVGAGDSGTYSCVAVSEAGEARRH 2294
Query: 347 LDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPPARLSWTRW 406
L+V PP +E+ G T L + G + L+C +P ++W +
Sbjct: 2295 FQLTVMEPPH-------------IEDSGQPTELSLTPGAPMELLCDAQGTPQPNITWHKD 2341
Query: 407 GQTVGPSQPSDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSVHYPPQLLGPSCSW 466
GQ + + + L ++ G +TC A+ P G+ S + V PP ++GP
Sbjct: 2342 GQALTRLENNSRATRVL---RVRDAGLYTCLAESPAGAIEKSFRVRVQAPPNIVGPRGPR 2398
Query: 467 EAEGLH-----CSCSSQASPAPSLRW 487
GL CS +A PAP + W
Sbjct: 2399 FVVGLAPGQLVLECSVEAEPAPKITW 2424
Score = 87.4 bits (215), Expect = 4e-17
Identities = 108/429 (25%), Positives = 171/429 (39%), Gaps = 73/429 (17%)
Query: 111 KGSCSLVIRDAQREDEAWYFFRVER--GSRVRHSFLSNAFFLKVTALTKKPDVYIPETLE 168
+G L I++AQ D+ Y +V G VR L+ ++V + P ET+
Sbjct: 1892 RGGQRLEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLT----VQVPPTFENPKT---ETVS 1944
Query: 169 P--GQPVTVICVFNWAFKKCPAPSFSWTGAALSPRRTRPSTSHFSVLS-------FTPSP 219
G P+ + C + PAP+ +W L R S++ V+S P
Sbjct: 1945 QVAGSPLVLTCDVSGV----PAPTVTW----LKDRMPVESSAVHGVVSRGGRLQLSRLQP 1996
Query: 220 QDHDTDLTCHVDFSRKGVSAQRTVRLRVAYAPKDLIISISHDNTSALELQGNVIYLEVQK 279
T TC + ++ A++ + V AP+ ++ ++ V +
Sbjct: 1997 AQAGT-YTCVAENTQ--AEARKDFVVAVLVAPRIRSSGVAREH-------------HVLE 2040
Query: 280 GQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTL------GLELRGVRAGDSGRYT 333
GQ +RL C AD QPP ++W+ L GP L L+G+RA D+G YT
Sbjct: 2041 GQEVRLDCEADGQPPPDVAWLKDGSPLGQD--MGPHLRFYLDGGSLVLKGLRASDAGAYT 2098
Query: 334 CRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVT 393
C A N G + ++V PP T+ + +L G+ + +VC
Sbjct: 2099 CVAHNPAGEDARLHTVNVLVPP------------TIKQGADGSGTLVSRPGELVTMVCPV 2146
Query: 394 HSSPPARLSWTRWGQTVGPSQPS----DPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSL 449
SPP +SW + G + SQ + L + +Q+ G FTC A P G +
Sbjct: 2147 RGSPPIHVSWLKDGLPLPLSQRTLLHGSGHTLRISKVQLADAGIFTCVAASPAGVADRNF 2206
Query: 450 SLSVHYPPQLLGPSCSWEAEGLHCS-----CSSQASPAPSLRWWL-GEELLEGNSSQG-S 502
+L V PP L + + S C ++ P P + W GE LL + QG S
Sbjct: 2207 TLQVQVPPVLEPVEFQNDVVVVRGSLVELPCEARGVPLPLVSWMKDGEPLLSQSLEQGPS 2266
Query: 503 FEVTPSSAG 511
++ AG
Sbjct: 2267 LQLEAVGAG 2275
Score = 83.6 bits (205), Expect = 6e-16
Identities = 63/224 (28%), Positives = 95/224 (42%), Gaps = 27/224 (12%)
Query: 277 VQKGQFLRLLCAADSQPPATLSWVLQDRVLSSS----HPWGPRTLGLELRGVRAGDSGRY 332
V + ++LLC A P ++W +L +S + G R L +L ++ D+G Y
Sbjct: 323 VMEDHLVQLLCEARGVPTPNITWFKDGALLPTSTKVVYTRGGRQL--QLGRAQSSDAGVY 380
Query: 333 TCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCV 392
TC+A N +G+ ++A L V PP T+ G + + G+ + L CV
Sbjct: 381 TCKASNAVGAAEKATRLDVYVPP------------TIEGAGGRPYVVKAVAGRPVALECV 428
Query: 393 THSSPPARLSWTRWGQTVGPSQPS----DPGVLELPPIQMEHEGEFTCHAQHPLGSQHVS 448
P LSW G V S S D VL L G ++C A P G +
Sbjct: 429 ARGHPSPTLSWHHEGLPVAESNESRLETDGSVLRLESPGEASSGLYSCVASSPAGEAVLQ 488
Query: 449 LSLSVHYPPQL-----LGPSCSWEAEGLHCSCSSQASPAPSLRW 487
S+ V PPQL LG + + L C + SP P+++W
Sbjct: 489 YSVEVQVPPQLLVAEGLGQVTTIVGQPLELPCQASGSPVPTIQW 532
Score = 79.0 bits (193), Expect = 1e-14
Identities = 67/227 (29%), Positives = 88/227 (38%), Gaps = 35/227 (15%)
Query: 285 LLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLGLELRGVRA-----GDSGRYTCRAENR 339
L C A PP +SW + +SS W T+ ++ R +R D+G Y C A N
Sbjct: 714 LECLASGVPPPDVSWFKGHQPVSS---WMGVTVSVDGRVLRIEQAQLSDAGSYRCVASNV 770
Query: 340 LGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPPA 399
GS + L V PP R L G PVL +RL C +P
Sbjct: 771 AGSTELRYGLRVNVPP-----------RITLPPSLPG---PVLVNTPVRLTCNATGAPSP 816
Query: 400 RLSWTRWGQTVGPSQPSDPG--------VLELPPIQMEHEGEFTCHAQHPLGSQHVSLSL 451
L W + G V P+ PG VL L + G ++C A +G + L
Sbjct: 817 TLMWLKDGNPVSPA--GTPGLQVFPGGRVLTLASARASDSGRYSCVAVSAVGEDRQDVVL 874
Query: 452 SVHYPPQLLGPSCSWEA---EGLHCSCSSQASPAPSLRWWLGEELLE 495
VH PP +LG + E + C S A P P L WW LE
Sbjct: 875 QVHMPPSILGEELNVSVVANESVALECQSHAMPPPVLSWWKDGRPLE 921
Score = 77.4 bits (189), Expect = 4e-14
Identities = 95/378 (25%), Positives = 157/378 (41%), Gaps = 47/378 (12%)
Query: 136 GSRVRHSFLSNAFFLKVTALTKKPDVYIPE-TLEPGQPVTVICVFNWAFKKCPAPSFSWT 194
G + +H LS L T L D E T+ P+++IC AF P+P+ +W
Sbjct: 1332 GEKTKHFQLS--VLLAPTILGGAEDSADEEVTVTVNNPISLICEA-LAF---PSPNITWM 1385
Query: 195 --GAALSPRRT---RPSTSHFSVLSFTPSPQDHDTDLTCHVDFSRKGVSAQRTVRLRVAY 249
GA R P T +L+ + ++ TC V + + A + + V
Sbjct: 1386 KDGAPFEASRNIQLLPGTHGLQILN---AQKEDAGQYTCVV--TNELGEAVKNYHVEVLI 1440
Query: 250 APKDLIISISHDNTSALELQGNVIYLEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSS 309
P SIS D+ + V ++ + L L C + + PP T+ W + ++ S
Sbjct: 1441 PP-----SISKDDPLG---EVGVKEVKTKVNSTLTLECESWAVPPPTIRWYKDGQPVTPS 1492
Query: 310 HPWGPRTLG----LELRGVRAGDSGRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQA 365
+ LG L+++ + DSGRY C A N G Q ++ +Q PP +V A
Sbjct: 1493 SRL--QVLGEGRLLQIQPTQVSDSGRYLCVATNVAGEDDQDFNVLIQVPPMFQKVGDFSA 1550
Query: 366 NRTVL----ENLGNGTSL-PVLEGQSLRLVCVTHSSPPARLSWTRWGQTVGP----SQPS 416
+L E G T ++E L C T++ PP L+W R Q + S
Sbjct: 1551 AFEILSREEEARGGVTEYREIVENNPAYLYCDTNAIPPPDLTWYREDQPLSAGDEVSVLQ 1610
Query: 417 DPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSVHYPPQLLGPSCSWEAE------- 469
VL++P ++ E+ G ++C A + +G + L V PP +LG + E
Sbjct: 1611 GGRVLQIPLVRAENAGRYSCKASNEVGEDWLHYELLVLTPPVILGDTEELVEEVTVNASS 1670
Query: 470 GLHCSCSSQASPAPSLRW 487
+ C + +P P++ W
Sbjct: 1671 TVSLQCPALGNPVPTISW 1688
Score = 76.6 bits (187), Expect = 7e-14
Identities = 63/233 (27%), Positives = 97/233 (41%), Gaps = 30/233 (12%)
Query: 270 GNVIYLEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSS---HPWGPRTLGLELRGVRA 326
G + + V + + L C + + PP LSW R L H + L L++
Sbjct: 884 GEELNVSVVANESVALECQSHAMPPPVLSWWKDGRPLEPRPGVHLSADKAL-LQVDRADV 942
Query: 327 GDSGRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQS 386
D+G YTC A N+ G ++ +L+V P + L +L V EG
Sbjct: 943 WDAGHYTCEALNQAGRSEKHYNLNVWVAP--------------VFPLRESHTLTVREGHP 988
Query: 387 LRLVCVTHSSPPARLSWTRWGQTV-----GPSQPSDPG-VLELPPIQMEHEGEFTCHAQH 440
L C P ++SW + GQ + G S G +L L Q+ EG +TC +
Sbjct: 989 TSLSCECRGVPFPKISWRKDGQPLPGEGAGLQHVSAVGRLLYLGQAQLAQEGTYTCECSN 1048
Query: 441 PLGSQHVSLSLSVHYPPQLLGP-----SCSWEAEGL-HCSCSSQASPAPSLRW 487
+G+ L L VH PPQ+ GP S +G+ C++ P P++ W
Sbjct: 1049 VVGNSSQDLQLEVHVPPQIAGPREPPTQVSVVQDGVATLECNATGKPPPTVTW 1101
Score = 76.3 bits (186), Expect = 9e-14
Identities = 62/229 (27%), Positives = 95/229 (41%), Gaps = 27/229 (11%)
Query: 283 LRLLCAADSQPPATLSWVLQDRVLSSSHPWG----PRTLGLELRGVRAGDSGRYTCRAEN 338
+RL C A P TL W+ +S + G P L L RA DSGRY+C A +
Sbjct: 804 VRLTCNATGAPSPTLMWLKDGNPVSPAGTPGLQVFPGGRVLTLASARASDSGRYSCVAVS 863
Query: 339 RLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPP 398
+G +Q + L V PP LG ++ V+ +S+ L C +H+ PP
Sbjct: 864 AVGEDRQDVVLQVHMPP---------------SILGEELNVSVVANESVALECQSHAMPP 908
Query: 399 ARLSWTRWGQTVGPSQ----PSDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSVH 454
LSW + G+ + P +D +L++ + G +TC A + G +L+V
Sbjct: 909 PVLSWWKDGRPLEPRPGVHLSADKALLQVDRADVWDAGHYTCEALNQAGRSEKHYNLNVW 968
Query: 455 YPPQL-LGPSCSW---EAEGLHCSCSSQASPAPSLRWWLGEELLEGNSS 499
P L S + E SC + P P + W + L G +
Sbjct: 969 VAPVFPLRESHTLTVREGHPTSLSCECRGVPFPKISWRKDGQPLPGEGA 1017
Score = 72.4 bits (176), Expect = 1e-12
Identities = 90/370 (24%), Positives = 142/370 (38%), Gaps = 45/370 (12%)
Query: 149 FLKVTALTKKPDVYIPETLEPGQPVTVICVFNWAFKKCPA-----PSFSW--TGAALSPR 201
+L L P V + +T E + VTV + + CPA P+ SW G SP
Sbjct: 1640 WLHYELLVLTPPVILGDTEELVEEVTVNASSTVSLQ-CPALGNPVPTISWLQNGLPFSPS 1698
Query: 202 RTRPSTSHFSVLSFTPSPQDHDTDLTCHVDFSRKGVSAQRTVRLRVAYAPKDLIISISHD 261
VL + + C + + SA++ LRV P+ I + +
Sbjct: 1699 PRLQVLEDGQVLQVSTAEVADAASYMCVAE--NQAGSAEKLFTLRVQVPPR--IAGLDLE 1754
Query: 262 NTSALELQGNVIYLEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWG--PRTLGL 319
+A+ L +V L C + P ++W + LS P T L
Sbjct: 1755 QVTAI-LNSSV-----------SLPCDVHAHPNPEVTWYKDSQALSLGEEVFLLPGTHTL 1802
Query: 320 ELRGVRAGDSGRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSL 379
+L R DSG YTC A N G Q+ + LSV PP QA R G ++
Sbjct: 1803 QLGRARLSDSGMYTCEALNAAGRDQKLVQLSVLVPP-----AFRQAPR------GPQDAV 1851
Query: 380 PVLEGQSLRLVCVTHSSPPARLSWTRWGQTVGPSQPSDP----GVLELPPIQMEHEGEFT 435
V G L C T + P ++W + GQ + +Q + LE+ Q+ +G ++
Sbjct: 1852 LVRVGDKAVLSCETDALPEPTVTWYKDGQPLVLAQRTQALRGGQRLEIQEAQVSDKGLYS 1911
Query: 436 CHAQHPLGSQHVSLSLSVHYPPQLLGPSCSWEAE----GLHCSCSSQASPAPSLRWWLGE 491
C + G + +L+V PP P ++ L +C PAP++ W
Sbjct: 1912 CKVSNVAGEAVRTFTLTVQVPPTFENPKTETVSQVAGSPLVLTCDVSGVPAPTVTWLKDR 1971
Query: 492 ELLEGNSSQG 501
+E ++ G
Sbjct: 1972 MPVESSAVHG 1981
Score = 72.4 bits (176), Expect = 1e-12
Identities = 83/355 (23%), Positives = 138/355 (38%), Gaps = 50/355 (14%)
Query: 166 TLEPGQPVTVICVFNWAFKKCPAPSFSWTGAALSPRRTRPSTSHFSVLSFTPSPQDHDTD 225
+L PG P+ ++C + P P+ +W + R ++ VL D
Sbjct: 2315 SLTPGAPMELLC----DAQGTPQPNITWHKDGQALTRLENNSRATRVLRV------RDAG 2364
Query: 226 LTCHVDFSRKGVSAQRTVRLRVAYAPKDLIISISHDNTSALELQGNVIYLEVQKGQFLRL 285
L + S G + +++ R+RV P + + +G + + GQ + L
Sbjct: 2365 LYTCLAESPAG-AIEKSFRVRVQAPP------------NIVGPRGPRFVVGLAPGQLV-L 2410
Query: 286 LCAADSQPPATLSWVLQDRVLSS-SHPWGP-RTLGLELRGVRAGDSGRYTCRAENRLGSQ 343
C+ +++P ++W VL +H P R L+L+ + DSG Y+C A N GS
Sbjct: 2411 ECSVEAEPAPKITWHRDGIVLQEDAHTQFPERGRFLQLQALSTADSGDYSCTARNAAGST 2470
Query: 344 QQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPPARLSW 403
A + + P +R N +V Q+ L C P +SW
Sbjct: 2471 SVAFRVEIHTVP-TIRSGPPAVNVSV--------------NQTALLPCQADGVPAPLVSW 2515
Query: 404 TRWGQTVGPSQPS----DPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSVHYPPQL 459
+ + P P G L + P+ + G + C A + GS L V PP
Sbjct: 2516 RKDRVPLDPRSPRFEILPEGSLRIQPVLAQDAGHYLCLASNSAGSDRQGRDLRVLEPP-A 2574
Query: 460 LGPSCSWEAEGLH----CSCSSQASPAPSLRWWLGEELLEGNSSQGSFEVTPSSA 510
+ PS S H C + SP P + WW + L+ QG++ + PS+A
Sbjct: 2575 IAPSPSNLTLTAHTPALLPCEASGSPKPLVVWWKDGQKLDFRLQQGAYRLLPSNA 2629
Score = 71.2 bits (173), Expect = 3e-12
Identities = 54/226 (23%), Positives = 94/226 (41%), Gaps = 24/226 (10%)
Query: 285 LLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLG--LELRGVRAGDSGRYTCRAENRLGS 342
L C A +PP T++W + + + + G L + +A +GRY+C AEN G
Sbjct: 1087 LECNATGKPPPTVTWERDGQPVGAELGLQLQNQGQSLHVERAQAAHTGRYSCVAENLAGR 1146
Query: 343 QQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPPARLS 402
++ +LSV PPE ++ +L T++ L L+C PP +
Sbjct: 1147 AERKFELSVLVPPE------------LIGDLDPLTNITAALHSPLTLLCEAMGIPPPAIR 1194
Query: 403 WTRWGQTVGPSQP----SDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSVHYPPQ 458
W R + V P + + +L++ Q + G ++C A + G + S+ V PP
Sbjct: 1195 WFRGEEPVSPGEDTYLLAGGWMLKMTQTQEQDSGLYSCLASNEAGEARRNFSVEVLVPPS 1254
Query: 459 LLGPSCS-----WEAEGLHCSCSSQASPAPSLRWWL-GEELLEGNS 498
+ + + H C+ P P L W+ G L G++
Sbjct: 1255 IENEDLEEVIKVLDGQTAHLMCNVTGHPQPKLTWFKDGRPLARGDA 1300
Score = 70.9 bits (172), Expect = 4e-12
Identities = 103/416 (24%), Positives = 160/416 (38%), Gaps = 75/416 (18%)
Query: 160 DVYIPETLE------------PGQPVTVICVFNWAFKKCPAPSFSWTGAALSPRRTRPST 207
DVY+P T+E G+PV + CV + P+P+ SW L + S
Sbjct: 398 DVYVPPTIEGAGGRPYVVKAVAGRPVALECVA----RGHPSPTLSWHHEGLPVAESNESR 453
Query: 208 --SHFSVLSFTPSPQDHDTDLTCHVDFSRKGVSA-QRTVRLRVAYAPKDLIISISHDNTS 264
+ SVL SP + + L V S G + Q +V ++V P L+++
Sbjct: 454 LETDGSVLRLE-SPGEASSGLYSCVASSPAGEAVLQYSVEVQV---PPQLLVA------- 502
Query: 265 ALELQGNVIYLEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLG--LELR 322
E G V + GQ L L C A P T+ W+ R + G L +
Sbjct: 503 --EGLGQVTTIV---GQPLELPCQASGSPVPTIQWLQNGRPAEELAGVQVASQGTTLHID 557
Query: 323 GVRAGDSGRYTCRAENRLGSQQQALDLSV--QYPPENLRVMVSQANRTVLENLGNGTSLP 380
V SG + C+A N G+ +++SV ++ P L V + Q + + +S P
Sbjct: 558 HVELDHSGLFACQATNEAGTAGAEVEVSVHGEWAPGVLEVPIGQYHW----GXEHHSSFP 613
Query: 381 VLEGQSLRLVCVTHSSPPARLSW----TRWGQTVG-PSQPSDPGVLELPPIQMEHEGEFT 435
+ H PP W + WG+ G P S P L++ + + EG +T
Sbjct: 614 AACDPPVHRGWGAHPKPPLVEGWCSPGSLWGEPTGIPVAYSLPPPLQIEKVDLRDEGIYT 673
Query: 436 CHAQHPLGSQHVSLSLSVHYPPQL-LGP--SCSWEAEGLHCSCSSQASPAPSLRWWLGEE 492
C A + G ++L V PP + GP E + C + P P + W+ G +
Sbjct: 674 CAATNLAGESKREVALKVLVPPNIEPGPVNKAVLENASVTLECLASGVPPPDVSWFKGHQ 733
Query: 493 LLEGNSSQGSFEVTPSSAGPWANSSLSLHG--------GLSSGLRLRCKAWNVHGA 540
P S+ W ++S+ G LS RC A NV G+
Sbjct: 734 --------------PVSS--WMGVTVSVDGRVLRIEQAQLSDAGSYRCVASNVAGS 773
Score = 70.1 bits (170), Expect = 7e-12
Identities = 64/233 (27%), Positives = 91/233 (39%), Gaps = 28/233 (12%)
Query: 275 LEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSS-----HPWGPRTLGLELRGVRAGDS 329
L V++G L C P +SW + L H L L L +
Sbjct: 981 LTVREGHPTSLSCECRGVPFPKISWRKDGQPLPGEGAGLQHVSAVGRL-LYLGQAQLAQE 1039
Query: 330 GRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRL 389
G YTC N +G+ Q L L V PP+ + T + V++ L
Sbjct: 1040 GTYTCECSNVVGNSSQDLQLEVHVPPQ------------IAGPREPPTQVSVVQDGVATL 1087
Query: 390 VCVTHSSPPARLSWTRWGQTVGPS---QPSDPG-VLELPPIQMEHEGEFTCHAQHPLGSQ 445
C PP ++W R GQ VG Q + G L + Q H G ++C A++ G
Sbjct: 1088 ECNATGKPPPTVTWERDGQPVGAELGLQLQNQGQSLHVERAQAAHTGRYSCVAENLAGRA 1147
Query: 446 HVSLSLSVHYPPQLLG---PSCSWEA---EGLHCSCSSQASPAPSLRWWLGEE 492
LSV PP+L+G P + A L C + P P++RW+ GEE
Sbjct: 1148 ERKFELSVLVPPELIGDLDPLTNITAALHSPLTLLCEAMGIPPPAIRWFRGEE 1200
Score = 69.3 bits (168), Expect = 1e-11
Identities = 77/289 (26%), Positives = 109/289 (37%), Gaps = 46/289 (15%)
Query: 275 LEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTL--------GLELRGVRA 326
+ V Q L C AD P +SW +DRV P PR+ L ++ V A
Sbjct: 2491 VNVSVNQTALLPCQADGVPAPLVSW-RKDRV-----PLDPRSPRFEILPEGSLRIQPVLA 2544
Query: 327 GDSGRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQS 386
D+G Y C A N GS +Q DL V PP + S +N T+ + P L
Sbjct: 2545 QDAGHYLCLASNSAGSDRQGRDLRVLEPP---AIAPSPSNLTLTAH------TPAL---- 2591
Query: 387 LRLVCVTHSSPPARLSWTRWGQTV------GPSQPSDPGVLELPPIQMEHEGEFTCHAQH 440
L C SP + W + GQ + G + L L + +F C +
Sbjct: 2592 --LPCEASGSPKPLVVWWKDGQKLDFRLQQGAYRLLPSNALLLTAPGPQDSAQFECVVSN 2649
Query: 441 PLGSQHVSLSLSVHYPPQLLGPSCSWEAEGLH---CSCSSQASPAPSLRWWLGEELLEGN 497
+G H ++VH PP + + + +C S PAP++ W L
Sbjct: 2650 EVGEAHRLYQVTVHVPPTIADDQTDFTVTMMAPVVLTCHSTGIPAPTVSWSKAGAQLGAR 2709
Query: 498 SSQGSFEVTPSSAGPWANSSLSLHGGLSSGLRLRCKAWNVHGAQSGSVF 546
S + V+PS A +L +H G R C A N G VF
Sbjct: 2710 GS--GYRVSPSGALE-IGQALPIHAG-----RYTCSARNSAGVAHKHVF 2750
Score = 68.9 bits (167), Expect = 1e-11
Identities = 100/424 (23%), Positives = 151/424 (35%), Gaps = 65/424 (15%)
Query: 83 GAPVATNNQSREVEMSTRDRFQLTGDPGKGSCSLVIRDAQREDEAWYFFRVERGSRVRHS 142
G PVA +N+SR + R + G+ G S V E Y V+ V
Sbjct: 443 GLPVAESNESRLETDGSVLRLESPGEASSGLYSCVASSPAGEAVLQYSVEVQ----VPPQ 498
Query: 143 FLSNAFFLKVTALTKKPDVYIPETLEPGQPVTVICVFNWAFKKCPAPSFSWTGAALSPRR 202
L +VT + +P + +P G PV I W PA + G ++ +
Sbjct: 499 LLVAEGLGQVTTIVGQP-LELP-CQASGSPVPTI---QWLQNGRPAEELA--GVQVASQG 551
Query: 203 TRPSTSHFSVLSFTPSPQDHDTDLTCHVDFSRKGVSAQRTVRLRVAYAPKDLIISISHDN 262
T H + DH C A+ V + +AP L + I +
Sbjct: 552 TTLHIDHVEL--------DHSGLFACQATNEAGTAGAEVEVSVHGEWAPGVLEVPIGQYH 603
Query: 263 TSALELQGNVIYLE--VQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRT---- 316
+ V +G A +PP W S WG T
Sbjct: 604 WGXEHHSSFPAACDPPVHRGW------GAHPKPPLVEGWC------SPGSLWGEPTGIPV 651
Query: 317 -----LGLELRGVRAGDSGRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLE 371
L++ V D G YTC A N G ++ + L V PP + N+ VLE
Sbjct: 652 AYSLPPPLQIEKVDLRDEGIYTCAATNLAGESKREVALKVLVPP---NIEPGPVNKAVLE 708
Query: 372 NLGNGTSLPVLEGQSLRLVCVTHSSPPARLSWTRWGQTV----GPSQPSDPGVLELPPIQ 427
N S+ L C+ PP +SW + Q V G + D VL + Q
Sbjct: 709 N------------ASVTLECLASGVPPPDVSWFKGHQPVSSWMGVTVSVDGRVLRIEQAQ 756
Query: 428 MEHEGEFTCHAQHPLGSQHVSLSLSVHYPPQL-LGPSCSWEA---EGLHCSCSSQASPAP 483
+ G + C A + GS + L V+ PP++ L PS + +C++ +P+P
Sbjct: 757 LSDAGSYRCVASNVAGSTELRYGLRVNVPPRITLPPSLPGPVLVNTPVRLTCNATGAPSP 816
Query: 484 SLRW 487
+L W
Sbjct: 817 TLMW 820
Score = 65.5 bits (158), Expect = 2e-10
Identities = 58/230 (25%), Positives = 92/230 (40%), Gaps = 26/230 (11%)
Query: 275 LEVQKGQFLRLLCAADSQPPATLSWVLQDRVLS--SSHPWGPRTLGLELRGVRAGDSGRY 332
++V GQ L+C P L+W R L+ +H P + L++ +G Y
Sbjct: 1264 IKVLDGQTAHLMCNVTGHPQPKLTWFKDGRPLARGDAHHISPDGVLLQVLQANLSSAGHY 1323
Query: 333 TCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCV 392
+C A N +G + + LSV P L A+ V + N S L+C
Sbjct: 1324 SCIAANAVGEKTKHFQLSVLLAPTILGGAEDSADEEVTVTVNNPIS----------LICE 1373
Query: 393 THSSPPARLSWTRWGQTVGPSQPSD--PGV--LELPPIQMEHEGEFTCHAQHPLGSQHVS 448
+ P ++W + G S+ PG L++ Q E G++TC + LG +
Sbjct: 1374 ALAFPSPNITWMKDGAPFEASRNIQLLPGTHGLQILNAQKEDAGQYTCVVTNELGEAVKN 1433
Query: 449 LSLSVHYPPQL-----LGPSCSWEAE-----GLHCSCSSQASPAPSLRWW 488
+ V PP + LG E + L C S A P P++RW+
Sbjct: 1434 YHVEVLIPPSISKDDPLGEVGVKEVKTKVNSTLTLECESWAVPPPTIRWY 1483
Score = 65.5 bits (158), Expect = 2e-10
Identities = 71/296 (23%), Positives = 111/296 (37%), Gaps = 47/296 (15%)
Query: 275 LEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLG----LELRGVRAGDSG 330
L +G L C A P ++W + +S + G T+ L ++ + D+G
Sbjct: 2856 LSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSGAE--GKFTIQPSGELLVKNLEGQDAG 2913
Query: 331 RYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLV 390
YTC AEN +G ++ + L++ P V L SL + G L L
Sbjct: 2914 TYTCTAENAVGRARRRVHLTILVLP-------------VFTTLPGDRSLRL--GDRLWLR 2958
Query: 391 CVTHSSPPARLSWTRWGQ--TVGPSQPSDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVS 448
C SP R+ WT + T G S+ L+ + E G + C A++ +G
Sbjct: 2959 CAARGSPTPRIGWTVNDRPVTEGVSEQDGGSTLQRAAVSREDSGTYVCWAENRVGRTQAV 3018
Query: 449 LSLSVHYPPQLLGPSCSWEAE----GLHCSCSSQASPAPSLRWWLGEELLEGNSSQGSFE 504
+ V P L G + S+ E + C + P P + W L G+ + +
Sbjct: 3019 SFVHVKEAPVLQGEAFSYLVEPVGGSIQLDCVVRGDPVPDIHWIKDGLPLRGSHLRHQLQ 3078
Query: 505 VTPSSAGPWANSSLSLH-GGLSSGLRLRCKAWNVHGA---------QSGSVFQLLP 550
N SL++H R +C A N G QS VFQ+ P
Sbjct: 3079 ----------NGSLTIHRTERDDAGRYQCLAENEMGVAKKVVILVLQSAPVFQVEP 3124
Score = 63.9 bits (154), Expect = 5e-10
Identities = 92/360 (25%), Positives = 141/360 (39%), Gaps = 56/360 (15%)
Query: 161 VYIPETLEPGQPVTVICVFNWAFKKC-----PAPSFSWT--GAALSPRRTRPSTSHFSVL 213
V++P T+ Q + + C PAP+ SW+ GA L R + S L
Sbjct: 2662 VHVPPTIADDQTDFTVTMMAPVVLTCHSTGIPAPTVSWSKAGAQLGARGSGYRVSPSGAL 2721
Query: 214 SFTPSPQDHDTDLTCHVDFSRKGVSAQRTVRLRVAYAPKDLIISISHDNTSALELQGNVI 273
+ H TC S GV A + V L V +P ++ +V+
Sbjct: 2722 EIGQALPIHAGRYTCSARNSA-GV-AHKHVFLTVQASP-------------VVKPLPSVV 2766
Query: 274 YLEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTL-GLELRGVRAG--DSG 330
++ L C A P T++W Q L+ + + L G +LR A D+G
Sbjct: 2767 RAVAEEEVLLP--CEASGIPRPTITW--QKEGLNVATGVSTQVLPGGQLRIAHASPEDAG 2822
Query: 331 RYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLV 390
Y C A+N GS L VQ PP V+EN L EG L
Sbjct: 2823 NYLCIAKNSAGSAMGKTRLVVQVPP-------------VIEN--GLPDLSTTEGSHAFLP 2867
Query: 391 CVTHSSPPARLSWTRWGQTVGPS------QPSDPGVLELPPIQMEHEGEFTCHAQHPLGS 444
C SP ++W + GQ V + QPS G L + ++ + G +TC A++ +G
Sbjct: 2868 CKARGSPEPNITWDKDGQPVSGAEGKFTIQPS--GELLVKNLEGQDAGTYTCTAENAVGR 2925
Query: 445 QHVSLSLSVHYPP---QLLGPSCSWEAEGLHCSCSSQASPAPSLRWWLGEE-LLEGNSSQ 500
+ L++ P L G + L C+++ SP P + W + + + EG S Q
Sbjct: 2926 ARRRVHLTILVLPVFTTLPGDRSLRLGDRLWLRCAARGSPTPRIGWTVNDRPVTEGVSEQ 2985
Score = 61.6 bits (148), Expect = 2e-09
Identities = 57/241 (23%), Positives = 95/241 (39%), Gaps = 37/241 (15%)
Query: 283 LRLLCAADSQPPATLSWVLQDRVLSSSHPWG--PRTLGLELRGVRAGDSGRYTCRAENRL 340
+ L+C A + P ++W+ +S P T GL++ + D+G+YTC N L
Sbjct: 1368 ISLICEALAFPSPNITWMKDGAPFEASRNIQLLPGTHGLQILNAQKEDAGQYTCVVTNEL 1427
Query: 341 GSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPPAR 400
G + + V PP S + L +G + +L L C + + PP
Sbjct: 1428 GEAVKNYHVEVLIPP-------SISKDDPLGEVGV-KEVKTKVNSTLTLECESWAVPPPT 1479
Query: 401 LSWTRWGQTVGPSQP----SDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSVHYP 456
+ W + GQ V PS + +L++ P Q+ G + C A + G ++ + P
Sbjct: 1480 IRWYKDGQPVTPSSRLQVLGEGRLLQIQPTQVSDSGRYLCVATNVAGEDDQDFNVLIQVP 1539
Query: 457 P--QLLGP--------SCSWEAEG-------------LHCSCSSQASPAPSLRWWLGEEL 493
P Q +G S EA G + C + A P P L W+ ++
Sbjct: 1540 PMFQKVGDFSAAFEILSREEEARGGVTEYREIVENNPAYLYCDTNAIPPPDLTWYREDQP 1599
Query: 494 L 494
L
Sbjct: 1600 L 1600
Score = 56.2 bits (134), Expect = 1e-07
Identities = 59/238 (24%), Positives = 91/238 (38%), Gaps = 33/238 (13%)
Query: 280 GQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLG------LELRGVRAGDSGRYT 333
G + L C P + W +DR P GP L + G GD GRY
Sbjct: 232 GADVELQCWTSGVPTPQVEWT-KDR--QPVLPGGPHLQVQEDGQVLRITGSHVGDEGRYQ 288
Query: 334 CRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVT 393
C A + G Q + L V PP + +N T + V+E ++L+C
Sbjct: 289 CVAFSPAGQQARDFQLRVHAPP-----TIWGSNET--------GEVAVMEDHLVQLLCEA 335
Query: 394 HSSPPARLSWTRWGQTVGPS----QPSDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSL 449
P ++W + G + S L+L Q G +TC A + +G+ +
Sbjct: 336 RGVPTPNITWFKDGALLPTSTKVVYTRGGRQLQLGRAQSSDAGVYTCKASNAVGAAEKAT 395
Query: 450 SLSVHYPPQLLG----PSCSWEAEG--LHCSCSSQASPAPSLRW-WLGEELLEGNSSQ 500
L V+ PP + G P G + C ++ P+P+L W G + E N S+
Sbjct: 396 RLDVYVPPTIEGAGGRPYVVKAVAGRPVALECVARGHPSPTLSWHHEGLPVAESNESR 453
Score = 54.3 bits (129), Expect = 4e-07
Identities = 84/349 (24%), Positives = 122/349 (34%), Gaps = 67/349 (19%)
Query: 187 PAPSFSWT-GAALSPRRTRPSTSHF---SVLSFTPSPQDHDTDLTCHVDFSRKGVSAQRT 242
P P +W G + P +P + S+ + SP D D C + + S R
Sbjct: 30 PKPQVTWRKGPSSEPLHGQPGVAVLEEGSLFLASVSPADSG-DYECQA--TNEVGSTSRR 86
Query: 243 VRLRVAYAPKDLIISISHDNTSALELQGNVIYLEVQKGQFLRLLCAADSQPPATLSWVLQ 302
+L V Y P SI D A + GQ L L C A+ P + W+
Sbjct: 87 AKL-VVYVPP----SIREDGRKA--------NVSGMAGQSLTLECDANGFPVPEIVWLKD 133
Query: 303 DRVLSSSHPW-------------GPRTL--GLEL------------RGVRAGDSGRYTCR 335
+++ W G R L G L RG +AG S +
Sbjct: 134 AQLVGVPLGWAGYGWDLGWGQVGGHRLLDEGQSLHFPRIQPGRSGRRGAQAGGSAQTKAP 193
Query: 336 AENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHS 395
L +Q PP V+ + A + VL L G + L C T
Sbjct: 194 WXAGLAGFEQFPTPHAFSPPAPPSVLGAGAAQEVLG----------LAGADVELQCWTSG 243
Query: 396 SPPARLSWTRWGQTVGPSQP-----SDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLS 450
P ++ WT+ Q V P P D VL + + EG + C A P G Q
Sbjct: 244 VPTPQVEWTKDRQPVLPGGPHLQVQEDGQVLRITGSHVGDEGRYQCVAFSPAGQQARDFQ 303
Query: 451 LSVHYPPQLLGPSCSWEAEGL-----HCSCSSQASPAPSLRWWLGEELL 494
L VH PP + G + + E + C ++ P P++ W+ LL
Sbjct: 304 LRVHAPPTIWGSNETGEVAVMEDHLVQLLCEARGVPTPNITWFKDGALL 352
Score = 51.6 bits (122), Expect = 2e-06
Identities = 79/357 (22%), Positives = 124/357 (34%), Gaps = 58/357 (16%)
Query: 153 TALTKKPDVYIPETLEPGQPVTVICVFNWAFKKC-----PAPSFSWTG--AALSPRRTRP 205
T++ + +++ T+ G P + V A C PAP SW L PR R
Sbjct: 2470 TSVAFRVEIHTVPTIRSGPPAVNVSVNQTALLPCQADGVPAPLVSWRKDRVPLDPRSPRF 2529
Query: 206 STSHFSVLSFTPSPQDHDTDLTCHVDFSRKGVSAQRTVRL----RVAYAPKDLIISISHD 261
L P C S R +R+ +A +P +L ++
Sbjct: 2530 EILPEGSLRIQPVLAQDAGHYLCLASNSAGSDRQGRDLRVLEPPAIAPSPSNLTLTA--- 2586
Query: 262 NTSALELQGNVIYLEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTL---- 317
+T AL L C A P + W + L G L
Sbjct: 2587 HTPAL------------------LPCEASGSPKPLVVWWKDGQKLDFRLQQGAYRLLPSN 2628
Query: 318 GLELRGVRAGDSGRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGT 377
L L DS ++ C N +G + ++V PP + Q + TV
Sbjct: 2629 ALLLTAPGPQDSAQFECVVSNEVGEAHRLYQVTVHVPPT---IADDQTDFTVT------M 2679
Query: 378 SLPVLEGQSLRLVCVTHSSPPARLSWTRWGQTVGPS----QPSDPGVLELPPIQMEHEGE 433
PV+ L C + P +SW++ G +G + S G LE+ H G
Sbjct: 2680 MAPVV------LTCHSTGIPAPTVSWSKAGAQLGARGSGYRVSPSGALEIGQALPIHAGR 2733
Query: 434 FTCHAQHPLGSQHVSLSLSVHYPPQLLG-PSC--SWEAEGLHCSCSSQASPAPSLRW 487
+TC A++ G H + L+V P + PS + E + C + P P++ W
Sbjct: 2734 YTCSARNSAGVAHKHVFLTVQASPVVKPLPSVVRAVAEEEVLLPCEASGIPRPTITW 2790
Score = 50.8 bits (120), Expect = 4e-06
Identities = 51/196 (26%), Positives = 72/196 (36%), Gaps = 20/196 (10%)
Query: 268 LQGNVI-YLEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLG-LELRGVR 325
LQG YL G ++L C P + W+ L SH G L +
Sbjct: 3029 LQGEAFSYLVEPVGGSIQLDCVVRGDPVPDIHWIKDGLPLRGSHLRHQLQNGSLTIHRTE 3088
Query: 326 AGDSGRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQ 385
D+GRY C AEN +G ++ + L +Q P V Q + V G
Sbjct: 3089 RDDAGRYQCLAENEMGVAKKVVILVLQSAP------VFQV---------EPQDMTVRSGD 3133
Query: 386 SLRLVCVTHSSPPARLSWTRWGQTVGPS---QPSDPGVLELPPIQMEHEGEFTCHAQHPL 442
+ L C P + W + GQ + S + G L L ++ G + C A + L
Sbjct: 3134 DVALRCQATGEPTPTIEWLQAGQPLRASRRLRTLPDGSLWLENVETGDAGTYDCVAHNLL 3193
Query: 443 GSQHVSLSLSVHYPPQ 458
GS L V PQ
Sbjct: 3194 GSATARAFLVVRGEPQ 3209
Score = 43.9 bits (102), Expect = 5e-04
Identities = 39/141 (27%), Positives = 60/141 (42%), Gaps = 24/141 (17%)
Query: 275 LEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTL---GLELRGVRAGDSGR 331
+ V+ G + L C A +P T+ W+ + L +S RTL L L V GD+G
Sbjct: 3127 MTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRASRRL--RTLPDGSLWLENVETGDAGT 3184
Query: 332 YTCRAENRLGSQQQALDLSVQYPPE-----------NLRVMVSQANRTVLENLGNGTS-- 378
Y C A N LGS L V+ P+ + V+ N +V++ +G S
Sbjct: 3185 YDCVAHNLLGSATARAFLVVRGEPQGSWGSMTGVINGRKFGVATLNTSVMQEAHSGVSSI 3244
Query: 379 ------LPVLEGQSLRLVCVT 393
+P G +R++ VT
Sbjct: 3245 HSSIRHVPANVGPLMRVLVVT 3265
Score = 39.7 bits (91), Expect = 0.010
Identities = 29/115 (25%), Positives = 46/115 (40%), Gaps = 12/115 (10%)
Query: 391 CVTHSSPPARLSWTRWGQTVGP--SQPS----DPGVLELPPIQMEHEGEFTCHAQHPLGS 444
C TH +P +++W R G + P QP + G L L + G++ C A + +GS
Sbjct: 24 CGTHGTPKPQVTW-RKGPSSEPLHGQPGVAVLEEGSLFLASVSPADSGDYECQATNEVGS 82
Query: 445 QHVSLSLSVHYPPQLLGPSCSWEAEG-----LHCSCSSQASPAPSLRWWLGEELL 494
L V+ PP + G L C + P P + W +L+
Sbjct: 83 TSRRAKLVVYVPPSIREDGRKANVSGMAGQSLTLECDANGFPVPEIVWLKDAQLV 137
>gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 5065
Score = 92.4 bits (228), Expect = 1e-18
Identities = 88/326 (26%), Positives = 135/326 (41%), Gaps = 44/326 (13%)
Query: 169 PGQPVTVICVFNWAFKKCPAPSFSWTGAALSPRRTRPSTSHFSVLSFTPSP-QDHDTDLT 227
PG+ VT++C + P SW L ++ + H S + S Q D +
Sbjct: 3327 PGELVTMVC----PVRGSPPIHVSWLKDGLPLPLSQRTLLHGSGHTLRISKVQLADAGIF 3382
Query: 228 CHVDFSRKGVSAQRTVRLRVAYAPKDLIISISHDNTSALELQGNVIYLEVQKGQFLRLLC 287
V S GV A R L+V P +E Q +V+ V +G + L C
Sbjct: 3383 TCVAASPAGV-ADRNFTLQVQVPPV----------LEPVEFQNDVV---VVRGSLVELPC 3428
Query: 288 AADSQPPATLSWVLQ-DRVLSSSHPWGPRTLGLELRGVRAGDSGRYTCRAENRLGSQQQA 346
A P +SW+ + +LS S GP L+L V AGDSG Y+C A + G ++
Sbjct: 3429 EARGVPLPLVSWMKDGEPLLSQSLEQGP---SLQLEAVGAGDSGTYSCVAVSEAGEARRH 3485
Query: 347 LDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPPARLSWTRW 406
L+V PP +E+ G T L + G + L+C +P ++W +
Sbjct: 3486 FQLTVMEPPH-------------IEDSGQPTELSLTPGAPMELLCDAQGTPQPNITWHKD 3532
Query: 407 GQTVGPSQPSDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSVHYPPQLLGPSCSW 466
GQ + + + L ++ G +TC A+ P G+ S + V PP ++GP
Sbjct: 3533 GQALTRLENNSRATRVL---RVRDAGLYTCLAESPAGAIEKSFRVRVQAPPNIVGPRGPR 3589
Query: 467 EAEGLH-----CSCSSQASPAPSLRW 487
GL CS +A PAP + W
Sbjct: 3590 FVVGLAPGQLVLECSVEAEPAPKITW 3615
Score = 87.4 bits (215), Expect = 4e-17
Identities = 108/429 (25%), Positives = 171/429 (39%), Gaps = 73/429 (17%)
Query: 111 KGSCSLVIRDAQREDEAWYFFRVER--GSRVRHSFLSNAFFLKVTALTKKPDVYIPETLE 168
+G L I++AQ D+ Y +V G VR L+ ++V + P ET+
Sbjct: 3083 RGGQRLEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLT----VQVPPTFENPKT---ETVS 3135
Query: 169 P--GQPVTVICVFNWAFKKCPAPSFSWTGAALSPRRTRPSTSHFSVLS-------FTPSP 219
G P+ + C + PAP+ +W L R S++ V+S P
Sbjct: 3136 QVAGSPLVLTCDVSGV----PAPTVTW----LKDRMPVESSAVHGVVSRGGRLQLSRLQP 3187
Query: 220 QDHDTDLTCHVDFSRKGVSAQRTVRLRVAYAPKDLIISISHDNTSALELQGNVIYLEVQK 279
T TC + ++ A++ + V AP+ ++ ++ V +
Sbjct: 3188 AQAGT-YTCVAENTQ--AEARKDFVVAVLVAPRIRSSGVAREH-------------HVLE 3231
Query: 280 GQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTL------GLELRGVRAGDSGRYT 333
GQ +RL C AD QPP ++W+ L GP L L+G+RA D+G YT
Sbjct: 3232 GQEVRLDCEADGQPPPDVAWLKDGSPLGQD--MGPHLRFYLDGGSLVLKGLRASDAGAYT 3289
Query: 334 CRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVT 393
C A N G + ++V PP T+ + +L G+ + +VC
Sbjct: 3290 CVAHNPAGEDARLHTVNVLVPP------------TIKQGADGSGTLVSRPGELVTMVCPV 3337
Query: 394 HSSPPARLSWTRWGQTVGPSQPS----DPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSL 449
SPP +SW + G + SQ + L + +Q+ G FTC A P G +
Sbjct: 3338 RGSPPIHVSWLKDGLPLPLSQRTLLHGSGHTLRISKVQLADAGIFTCVAASPAGVADRNF 3397
Query: 450 SLSVHYPPQLLGPSCSWEAEGLHCS-----CSSQASPAPSLRWWL-GEELLEGNSSQG-S 502
+L V PP L + + S C ++ P P + W GE LL + QG S
Sbjct: 3398 TLQVQVPPVLEPVEFQNDVVVVRGSLVELPCEARGVPLPLVSWMKDGEPLLSQSLEQGPS 3457
Query: 503 FEVTPSSAG 511
++ AG
Sbjct: 3458 LQLEAVGAG 3466
Score = 83.6 bits (205), Expect = 6e-16
Identities = 63/224 (28%), Positives = 95/224 (42%), Gaps = 27/224 (12%)
Query: 277 VQKGQFLRLLCAADSQPPATLSWVLQDRVLSSS----HPWGPRTLGLELRGVRAGDSGRY 332
V + ++LLC A P ++W +L +S + G R L +L ++ D+G Y
Sbjct: 1514 VMEDHLVQLLCEARGVPTPNITWFKDGALLPTSTKVVYTRGGRQL--QLGRAQSSDAGVY 1571
Query: 333 TCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCV 392
TC+A N +G+ ++A L V PP T+ G + + G+ + L CV
Sbjct: 1572 TCKASNAVGAAEKATRLDVYVPP------------TIEGAGGRPYVVKAVAGRPVALECV 1619
Query: 393 THSSPPARLSWTRWGQTVGPSQPS----DPGVLELPPIQMEHEGEFTCHAQHPLGSQHVS 448
P LSW G V S S D VL L G ++C A P G +
Sbjct: 1620 ARGHPSPTLSWHHEGLPVAESNESRLETDGSVLRLESPGEASSGLYSCVASSPAGEAVLQ 1679
Query: 449 LSLSVHYPPQL-----LGPSCSWEAEGLHCSCSSQASPAPSLRW 487
S+ V PPQL LG + + L C + SP P+++W
Sbjct: 1680 YSVEVQVPPQLLVAEGLGQVTTIVGQPLELPCQASGSPVPTIQW 1723
Score = 83.2 bits (204), Expect = 8e-16
Identities = 91/339 (26%), Positives = 130/339 (38%), Gaps = 60/339 (17%)
Query: 187 PAPSFSWT-GAALSPRRTRPSTSHF---SVLSFTPSPQDHDTDLTCHVDFSRKGVSAQRT 242
P P +W G + P +P + S+ + SP D D C + + S R
Sbjct: 1234 PKPQVTWRKGPSSEPLHGQPGVAVLEEGSLFLASVSPADSG-DYECQA--TNEVGSTSRR 1290
Query: 243 VRLRVAYAPKDLIISISHDNTSALELQGNVIYLEVQKGQFLRLLCAADSQPPATLSWVLQ 302
+L V Y P SI D A + GQ L L C A+ P + W+
Sbjct: 1291 AKL-VVYVPP----SIREDGRKA--------NVSGMAGQSLTLECDANGFPVPEIVWLKD 1337
Query: 303 DRVLSSSHPW-------------GPRTL----GLELRGVRAGDSGRYTCRAENRLGSQQQ 345
+++ W G R L L ++ GDSG Y+CRAEN+ G+ Q+
Sbjct: 1338 AQLVGVPLGWAGYGWDLGWGQVGGHRLLDEGQSLHFPRIQEGDSGLYSCRAENQAGTAQR 1397
Query: 346 ALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPPARLSWTR 405
L V PP L +Q E LG L G + L C T P ++ WT+
Sbjct: 1398 DFHLLVLTPPSVLGAGAAQ------EVLG-------LAGADVELQCWTSGVPTPQVEWTK 1444
Query: 406 WGQTVGPSQP-----SDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSVHYPPQLL 460
Q V P P D VL + + EG + C A P G Q L VH PP +
Sbjct: 1445 DRQPVLPGGPHLQVQEDGQVLRITGSHVGDEGRYQCVAFSPAGQQARDFQLRVHAPPTIW 1504
Query: 461 GPSCSWEAEGL-----HCSCSSQASPAPSLRWWLGEELL 494
G + + E + C ++ P P++ W+ LL
Sbjct: 1505 GSNETGEVAVMEDHLVQLLCEARGVPTPNITWFKDGALL 1543
Score = 82.8 bits (203), Expect = 1e-15
Identities = 73/272 (26%), Positives = 113/272 (41%), Gaps = 35/272 (12%)
Query: 279 KGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLG-LELRGVRAGDSGRYTCRAE 337
+G +++ C+A P +SW + + L G L ++GV D+G Y+C+A
Sbjct: 621 QGVEVKVSCSASGYPTPHISWSRESQALQEDSRIHVDAQGTLIIQGVAPEDAGNYSCQAT 680
Query: 338 NRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSP 397
N +G+ Q+ + L PP VS N VL V G+ LVC P
Sbjct: 681 NEVGTDQETVTLYYTDPPS-----VSAVNAVVL----------VAVGEEAVLVCEASGVP 725
Query: 398 PARLSWTRWG-QTVGPSQPSDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSVHYP 456
P R+ W R G + + + S G L +P Q G +TC A + LG + L+V +
Sbjct: 726 PPRVIWYRGGLEMILAPEGSSSGKLRIPAAQERDAGTYTCRAVNELGDASAEIQLAVGHA 785
Query: 457 PQL--LGPSCSWE-AEGLHCSCSSQASPAPSLRWW------LGEELLEGNSSQGS----- 502
PQL L + E +C + P P++ W LG L G S+
Sbjct: 786 PQLTELPRDVTVELGRSALLACRATGRPPPTVTWRRGDGQPLGLRLGAGRGSRSRQPDSG 845
Query: 503 ---FE-VTPSSAGPWANSSLSLHGGLSSGLRL 530
FE V P P+ + ++ G + + RL
Sbjct: 846 VLFFESVAPEDQAPYVCEARNVFGKVQAEARL 877
Score = 79.0 bits (193), Expect = 1e-14
Identities = 67/227 (29%), Positives = 88/227 (38%), Gaps = 35/227 (15%)
Query: 285 LLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLGLELRGVRA-----GDSGRYTCRAENR 339
L C A PP +SW + +SS W T+ ++ R +R D+G Y C A N
Sbjct: 1905 LECLASGVPPPDVSWFKGHQPVSS---WMGVTVSVDGRVLRIEQAQLSDAGSYRCVASNV 1961
Query: 340 LGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPPA 399
GS + L V PP R L G PVL +RL C +P
Sbjct: 1962 AGSTELRYGLRVNVPP-----------RITLPPSLPG---PVLVNTPVRLTCNATGAPSP 2007
Query: 400 RLSWTRWGQTVGPSQPSDPG--------VLELPPIQMEHEGEFTCHAQHPLGSQHVSLSL 451
L W + G V P+ PG VL L + G ++C A +G + L
Sbjct: 2008 TLMWLKDGNPVSPA--GTPGLQVFPGGRVLTLASARASDSGRYSCVAVSAVGEDRQDVVL 2065
Query: 452 SVHYPPQLLGPSCSWEA---EGLHCSCSSQASPAPSLRWWLGEELLE 495
VH PP +LG + E + C S A P P L WW LE
Sbjct: 2066 QVHMPPSILGEELNVSVVANESVALECQSHAMPPPVLSWWKDGRPLE 2112
Score = 77.4 bits (189), Expect = 4e-14
Identities = 95/378 (25%), Positives = 157/378 (41%), Gaps = 47/378 (12%)
Query: 136 GSRVRHSFLSNAFFLKVTALTKKPDVYIPE-TLEPGQPVTVICVFNWAFKKCPAPSFSWT 194
G + +H LS L T L D E T+ P+++IC AF P+P+ +W
Sbjct: 2523 GEKTKHFQLS--VLLAPTILGGAEDSADEEVTVTVNNPISLICEA-LAF---PSPNITWM 2576
Query: 195 --GAALSPRRT---RPSTSHFSVLSFTPSPQDHDTDLTCHVDFSRKGVSAQRTVRLRVAY 249
GA R P T +L+ + ++ TC V + + A + + V
Sbjct: 2577 KDGAPFEASRNIQLLPGTHGLQILN---AQKEDAGQYTCVV--TNELGEAVKNYHVEVLI 2631
Query: 250 APKDLIISISHDNTSALELQGNVIYLEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSS 309
P SIS D+ + V ++ + L L C + + PP T+ W + ++ S
Sbjct: 2632 PP-----SISKDDPLG---EVGVKEVKTKVNSTLTLECESWAVPPPTIRWYKDGQPVTPS 2683
Query: 310 HPWGPRTLG----LELRGVRAGDSGRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQA 365
+ LG L+++ + DSGRY C A N G Q ++ +Q PP +V A
Sbjct: 2684 SRL--QVLGEGRLLQIQPTQVSDSGRYLCVATNVAGEDDQDFNVLIQVPPMFQKVGDFSA 2741
Query: 366 NRTVL----ENLGNGTSL-PVLEGQSLRLVCVTHSSPPARLSWTRWGQTVGP----SQPS 416
+L E G T ++E L C T++ PP L+W R Q + S
Sbjct: 2742 AFEILSREEEARGGVTEYREIVENNPAYLYCDTNAIPPPDLTWYREDQPLSAGDEVSVLQ 2801
Query: 417 DPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSVHYPPQLLGPSCSWEAE------- 469
VL++P ++ E+ G ++C A + +G + L V PP +LG + E
Sbjct: 2802 GGRVLQIPLVRAENAGRYSCKASNEVGEDWLHYELLVLTPPVILGDTEELVEEVTVNASS 2861
Query: 470 GLHCSCSSQASPAPSLRW 487
+ C + +P P++ W
Sbjct: 2862 TVSLQCPALGNPVPTISW 2879
Score = 76.6 bits (187), Expect = 7e-14
Identities = 63/233 (27%), Positives = 97/233 (41%), Gaps = 30/233 (12%)
Query: 270 GNVIYLEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSS---HPWGPRTLGLELRGVRA 326
G + + V + + L C + + PP LSW R L H + L L++
Sbjct: 2075 GEELNVSVVANESVALECQSHAMPPPVLSWWKDGRPLEPRPGVHLSADKAL-LQVDRADV 2133
Query: 327 GDSGRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQS 386
D+G YTC A N+ G ++ +L+V P + L +L V EG
Sbjct: 2134 WDAGHYTCEALNQAGHSEKHYNLNVWVAP--------------VFPLRESHTLTVREGHP 2179
Query: 387 LRLVCVTHSSPPARLSWTRWGQTV-----GPSQPSDPG-VLELPPIQMEHEGEFTCHAQH 440
L C P ++SW + GQ + G S G +L L Q+ EG +TC +
Sbjct: 2180 TSLSCECRGVPFPKISWRKDGQPLPGEGAGLQHVSAVGRLLYLGQAQLAQEGTYTCECSN 2239
Query: 441 PLGSQHVSLSLSVHYPPQLLGP-----SCSWEAEGL-HCSCSSQASPAPSLRW 487
+G+ L L VH PPQ+ GP S +G+ C++ P P++ W
Sbjct: 2240 VVGNSSQDLQLEVHVPPQIAGPREPPTQVSVVQDGVATLECNATGKPPPTVTW 2292
Score = 76.3 bits (186), Expect = 9e-14
Identities = 62/229 (27%), Positives = 95/229 (41%), Gaps = 27/229 (11%)
Query: 283 LRLLCAADSQPPATLSWVLQDRVLSSSHPWG----PRTLGLELRGVRAGDSGRYTCRAEN 338
+RL C A P TL W+ +S + G P L L RA DSGRY+C A +
Sbjct: 1995 VRLTCNATGAPSPTLMWLKDGNPVSPAGTPGLQVFPGGRVLTLASARASDSGRYSCVAVS 2054
Query: 339 RLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPP 398
+G +Q + L V PP LG ++ V+ +S+ L C +H+ PP
Sbjct: 2055 AVGEDRQDVVLQVHMPP---------------SILGEELNVSVVANESVALECQSHAMPP 2099
Query: 399 ARLSWTRWGQTVGPSQ----PSDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSVH 454
LSW + G+ + P +D +L++ + G +TC A + G +L+V
Sbjct: 2100 PVLSWWKDGRPLEPRPGVHLSADKALLQVDRADVWDAGHYTCEALNQAGHSEKHYNLNVW 2159
Query: 455 YPPQL-LGPSCSW---EAEGLHCSCSSQASPAPSLRWWLGEELLEGNSS 499
P L S + E SC + P P + W + L G +
Sbjct: 2160 VAPVFPLRESHTLTVREGHPTSLSCECRGVPFPKISWRKDGQPLPGEGA 2208
Score = 72.4 bits (176), Expect = 1e-12
Identities = 90/370 (24%), Positives = 142/370 (38%), Gaps = 45/370 (12%)
Query: 149 FLKVTALTKKPDVYIPETLEPGQPVTVICVFNWAFKKCPA-----PSFSW--TGAALSPR 201
+L L P V + +T E + VTV + + CPA P+ SW G SP
Sbjct: 2831 WLHYELLVLTPPVILGDTEELVEEVTVNASSTVSLQ-CPALGNPVPTISWLQNGLPFSPS 2889
Query: 202 RTRPSTSHFSVLSFTPSPQDHDTDLTCHVDFSRKGVSAQRTVRLRVAYAPKDLIISISHD 261
VL + + C + + SA++ LRV P+ I + +
Sbjct: 2890 PRLQVLEDGQVLQVSTAEVADAASYMCVAE--NQAGSAEKLFTLRVQVPPR--IAGLDLE 2945
Query: 262 NTSALELQGNVIYLEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWG--PRTLGL 319
+A+ L +V L C + P ++W + LS P T L
Sbjct: 2946 QVTAI-LNSSV-----------SLPCDVHAHPNPEVTWYKDSQALSLGEEVFLLPGTHTL 2993
Query: 320 ELRGVRAGDSGRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSL 379
+L R DSG YTC A N G Q+ + LSV PP QA R G ++
Sbjct: 2994 QLGRARLSDSGMYTCEALNAAGRDQKLVQLSVLVPP-----AFRQAPR------GPQDAV 3042
Query: 380 PVLEGQSLRLVCVTHSSPPARLSWTRWGQTVGPSQPSDP----GVLELPPIQMEHEGEFT 435
V G L C T + P ++W + GQ + +Q + LE+ Q+ +G ++
Sbjct: 3043 LVRVGDKAVLSCETDALPEPTVTWYKDGQPLVLAQRTQALRGGQRLEIQEAQVSDKGLYS 3102
Query: 436 CHAQHPLGSQHVSLSLSVHYPPQLLGPSCSWEAE----GLHCSCSSQASPAPSLRWWLGE 491
C + G + +L+V PP P ++ L +C PAP++ W
Sbjct: 3103 CKVSNVAGEAVRTFTLTVQVPPTFENPKTETVSQVAGSPLVLTCDVSGVPAPTVTWLKDR 3162
Query: 492 ELLEGNSSQG 501
+E ++ G
Sbjct: 3163 MPVESSAVHG 3172
Score = 72.4 bits (176), Expect = 1e-12
Identities = 83/355 (23%), Positives = 138/355 (38%), Gaps = 50/355 (14%)
Query: 166 TLEPGQPVTVICVFNWAFKKCPAPSFSWTGAALSPRRTRPSTSHFSVLSFTPSPQDHDTD 225
+L PG P+ ++C + P P+ +W + R ++ VL D
Sbjct: 3506 SLTPGAPMELLC----DAQGTPQPNITWHKDGQALTRLENNSRATRVLRV------RDAG 3555
Query: 226 LTCHVDFSRKGVSAQRTVRLRVAYAPKDLIISISHDNTSALELQGNVIYLEVQKGQFLRL 285
L + S G + +++ R+RV P + + +G + + GQ + L
Sbjct: 3556 LYTCLAESPAG-AIEKSFRVRVQAPP------------NIVGPRGPRFVVGLAPGQLV-L 3601
Query: 286 LCAADSQPPATLSWVLQDRVLSS-SHPWGP-RTLGLELRGVRAGDSGRYTCRAENRLGSQ 343
C+ +++P ++W VL +H P R L+L+ + DSG Y+C A N GS
Sbjct: 3602 ECSVEAEPAPKITWHRDGIVLQEDAHTQFPERGRFLQLQALSTADSGDYSCTARNAAGST 3661
Query: 344 QQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPPARLSW 403
A + + P +R N +V Q+ L C P +SW
Sbjct: 3662 SVAFRVEIHTVP-TIRSGPPAVNVSV--------------NQTALLPCQADGVPAPLVSW 3706
Query: 404 TRWGQTVGPSQPS----DPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSVHYPPQL 459
+ + P P G L + P+ + G + C A + GS L V PP
Sbjct: 3707 RKDRVPLDPRSPRFEILPEGSLRIQPVLAQDAGHYLCLASNSAGSDRQGRDLRVLEPP-A 3765
Query: 460 LGPSCSWEAEGLH----CSCSSQASPAPSLRWWLGEELLEGNSSQGSFEVTPSSA 510
+ PS S H C + SP P + WW + L+ QG++ + PS+A
Sbjct: 3766 IAPSPSNLTLTAHTPALLPCEASGSPKPLVVWWKDGQKLDFRLQQGAYRLLPSNA 3820
Score = 71.2 bits (173), Expect = 3e-12
Identities = 54/226 (23%), Positives = 94/226 (41%), Gaps = 24/226 (10%)
Query: 285 LLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLG--LELRGVRAGDSGRYTCRAENRLGS 342
L C A +PP T++W + + + + G L + +A +GRY+C AEN G
Sbjct: 2278 LECNATGKPPPTVTWERDGQPVGAELGLQLQNQGQSLHVERAQAAHTGRYSCVAENLAGR 2337
Query: 343 QQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPPARLS 402
++ +LSV PPE ++ +L T++ L L+C PP +
Sbjct: 2338 AERKFELSVLVPPE------------LIGDLDPLTNITAALHSPLTLLCEAMGIPPPAIR 2385
Query: 403 WTRWGQTVGPSQP----SDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSVHYPPQ 458
W R + V P + + +L++ Q + G ++C A + G + S+ V PP
Sbjct: 2386 WFRGEEPVSPGEDTYLLAGGWMLKMTQTQEQDSGLYSCLASNEAGEARRNFSVEVLVPPS 2445
Query: 459 LLGPSCS-----WEAEGLHCSCSSQASPAPSLRWWL-GEELLEGNS 498
+ + + H C+ P P L W+ G L G++
Sbjct: 2446 IENEDLEEVIKVLDGQTAHLMCNVTGHPQPKLTWFKDGRPLARGDA 2491
Score = 70.9 bits (172), Expect = 4e-12
Identities = 103/416 (24%), Positives = 160/416 (38%), Gaps = 75/416 (18%)
Query: 160 DVYIPETLE------------PGQPVTVICVFNWAFKKCPAPSFSWTGAALSPRRTRPST 207
DVY+P T+E G+PV + CV + P+P+ SW L + S
Sbjct: 1589 DVYVPPTIEGAGGRPYVVKAVAGRPVALECVA----RGHPSPTLSWHHEGLPVAESNESR 1644
Query: 208 --SHFSVLSFTPSPQDHDTDLTCHVDFSRKGVSA-QRTVRLRVAYAPKDLIISISHDNTS 264
+ SVL SP + + L V S G + Q +V ++V P L+++
Sbjct: 1645 LETDGSVLRLE-SPGEASSGLYSCVASSPAGEAVLQYSVEVQV---PPQLLVA------- 1693
Query: 265 ALELQGNVIYLEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLG--LELR 322
E G V + GQ L L C A P T+ W+ R + G L +
Sbjct: 1694 --EGLGQVTTIV---GQPLELPCQASGSPVPTIQWLQNGRPAEELAGVQVASQGTTLHID 1748
Query: 323 GVRAGDSGRYTCRAENRLGSQQQALDLSV--QYPPENLRVMVSQANRTVLENLGNGTSLP 380
V SG + C+A N G+ +++SV ++ P L V + Q + + +S P
Sbjct: 1749 HVELDHSGLFACQATNEAGTAGAEVEVSVHGEWAPGVLEVPIGQYHW----GXEHHSSFP 1804
Query: 381 VLEGQSLRLVCVTHSSPPARLSW----TRWGQTVG-PSQPSDPGVLELPPIQMEHEGEFT 435
+ H PP W + WG+ G P S P L++ + + EG +T
Sbjct: 1805 AACDPPVHRGWGAHPKPPLVEGWCSPGSLWGEPTGIPVAYSLPPPLQIEKVDLRDEGIYT 1864
Query: 436 CHAQHPLGSQHVSLSLSVHYPPQL-LGP--SCSWEAEGLHCSCSSQASPAPSLRWWLGEE 492
C A + G ++L V PP + GP E + C + P P + W+ G +
Sbjct: 1865 CAATNLAGESKREVALKVLVPPNIEPGPVNKAVLENASVTLECLASGVPPPDVSWFKGHQ 1924
Query: 493 LLEGNSSQGSFEVTPSSAGPWANSSLSLHG--------GLSSGLRLRCKAWNVHGA 540
P S+ W ++S+ G LS RC A NV G+
Sbjct: 1925 --------------PVSS--WMGVTVSVDGRVLRIEQAQLSDAGSYRCVASNVAGS 1964
Score = 70.5 bits (171), Expect = 5e-12
Identities = 59/231 (25%), Positives = 89/231 (38%), Gaps = 29/231 (12%)
Query: 275 LEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLGLELRGVRAGDSGRYTC 334
L+V G+ L L C A+ P LSW VL P G + +R D+GRY C
Sbjct: 1129 LKVLVGEALDLNCVAEGNPEPQLSWSKDGVVLQGRGPQG----SVHFAAIRTSDAGRYRC 1184
Query: 335 RAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTH 394
A N G ++L V PP + +LE + G++ L C
Sbjct: 1185 EASNSAGVDAWEVELRVLEPPH----WGADETSGLLERVA---------GENASLPCPAR 1231
Query: 395 SSPPARLSWTRWGQTVGP--SQPS----DPGVLELPPIQMEHEGEFTCHAQHPLGSQHVS 448
+P +++W R G + P QP + G L L + G++ C A + +GS
Sbjct: 1232 GTPKPQVTW-RKGPSSEPLHGQPGVAVLEEGSLFLASVSPADSGDYECQATNEVGSTSRR 1290
Query: 449 LSLSVHYPPQLLGPSCSWEAEG-----LHCSCSSQASPAPSLRWWLGEELL 494
L V+ PP + G L C + P P + W +L+
Sbjct: 1291 AKLVVYVPPSIREDGRKANVSGMAGQSLTLECDANGFPVPEIVWLKDAQLV 1341
Score = 70.1 bits (170), Expect = 7e-12
Identities = 64/233 (27%), Positives = 91/233 (39%), Gaps = 28/233 (12%)
Query: 275 LEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSS-----HPWGPRTLGLELRGVRAGDS 329
L V++G L C P +SW + L H L L L +
Sbjct: 2172 LTVREGHPTSLSCECRGVPFPKISWRKDGQPLPGEGAGLQHVSAVGRL-LYLGQAQLAQE 2230
Query: 330 GRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRL 389
G YTC N +G+ Q L L V PP+ + T + V++ L
Sbjct: 2231 GTYTCECSNVVGNSSQDLQLEVHVPPQ------------IAGPREPPTQVSVVQDGVATL 2278
Query: 390 VCVTHSSPPARLSWTRWGQTVGPS---QPSDPG-VLELPPIQMEHEGEFTCHAQHPLGSQ 445
C PP ++W R GQ VG Q + G L + Q H G ++C A++ G
Sbjct: 2279 ECNATGKPPPTVTWERDGQPVGAELGLQLQNQGQSLHVERAQAAHTGRYSCVAENLAGRA 2338
Query: 446 HVSLSLSVHYPPQLLG---PSCSWEA---EGLHCSCSSQASPAPSLRWWLGEE 492
LSV PP+L+G P + A L C + P P++RW+ GEE
Sbjct: 2339 ERKFELSVLVPPELIGDLDPLTNITAALHSPLTLLCEAMGIPPPAIRWFRGEE 2391
Score = 69.3 bits (168), Expect = 1e-11
Identities = 77/289 (26%), Positives = 109/289 (37%), Gaps = 46/289 (15%)
Query: 275 LEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTL--------GLELRGVRA 326
+ V Q L C AD P +SW +DRV P PR+ L ++ V A
Sbjct: 3682 VNVSVNQTALLPCQADGVPAPLVSW-RKDRV-----PLDPRSPRFEILPEGSLRIQPVLA 3735
Query: 327 GDSGRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQS 386
D+G Y C A N GS +Q DL V PP + S +N T+ + P L
Sbjct: 3736 QDAGHYLCLASNSAGSDRQGRDLRVLEPP---AIAPSPSNLTLTAH------TPAL---- 3782
Query: 387 LRLVCVTHSSPPARLSWTRWGQTV------GPSQPSDPGVLELPPIQMEHEGEFTCHAQH 440
L C SP + W + GQ + G + L L + +F C +
Sbjct: 3783 --LPCEASGSPKPLVVWWKDGQKLDFRLQQGAYRLLPSNALLLTAPGPQDSAQFECVVSN 3840
Query: 441 PLGSQHVSLSLSVHYPPQLLGPSCSWEAEGLH---CSCSSQASPAPSLRWWLGEELLEGN 497
+G H ++VH PP + + + +C S PAP++ W L
Sbjct: 3841 EVGEAHRLYQVTVHVPPTIADDQTDFTVTMMAPVVLTCHSTGIPAPTVSWSKAGAQLGAR 3900
Query: 498 SSQGSFEVTPSSAGPWANSSLSLHGGLSSGLRLRCKAWNVHGAQSGSVF 546
S + V+PS A +L +H G R C A N G VF
Sbjct: 3901 GS--GYRVSPSGALE-IGQALPIHAG-----RYTCSARNSAGVAHKHVF 3941
Score = 68.9 bits (167), Expect = 1e-11
Identities = 100/424 (23%), Positives = 151/424 (35%), Gaps = 65/424 (15%)
Query: 83 GAPVATNNQSREVEMSTRDRFQLTGDPGKGSCSLVIRDAQREDEAWYFFRVERGSRVRHS 142
G PVA +N+SR + R + G+ G S V E Y V+ V
Sbjct: 1634 GLPVAESNESRLETDGSVLRLESPGEASSGLYSCVASSPAGEAVLQYSVEVQ----VPPQ 1689
Query: 143 FLSNAFFLKVTALTKKPDVYIPETLEPGQPVTVICVFNWAFKKCPAPSFSWTGAALSPRR 202
L +VT + +P + +P G PV I W PA + G ++ +
Sbjct: 1690 LLVAEGLGQVTTIVGQP-LELP-CQASGSPVPTI---QWLQNGRPAEELA--GVQVASQG 1742
Query: 203 TRPSTSHFSVLSFTPSPQDHDTDLTCHVDFSRKGVSAQRTVRLRVAYAPKDLIISISHDN 262
T H + DH C A+ V + +AP L + I +
Sbjct: 1743 TTLHIDHVEL--------DHSGLFACQATNEAGTAGAEVEVSVHGEWAPGVLEVPIGQYH 1794
Query: 263 TSALELQGNVIYLE--VQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRT---- 316
+ V +G A +PP W S WG T
Sbjct: 1795 WGXEHHSSFPAACDPPVHRGW------GAHPKPPLVEGWC------SPGSLWGEPTGIPV 1842
Query: 317 -----LGLELRGVRAGDSGRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLE 371
L++ V D G YTC A N G ++ + L V PP + N+ VLE
Sbjct: 1843 AYSLPPPLQIEKVDLRDEGIYTCAATNLAGESKREVALKVLVPP---NIEPGPVNKAVLE 1899
Query: 372 NLGNGTSLPVLEGQSLRLVCVTHSSPPARLSWTRWGQTV----GPSQPSDPGVLELPPIQ 427
N S+ L C+ PP +SW + Q V G + D VL + Q
Sbjct: 1900 N------------ASVTLECLASGVPPPDVSWFKGHQPVSSWMGVTVSVDGRVLRIEQAQ 1947
Query: 428 MEHEGEFTCHAQHPLGSQHVSLSLSVHYPPQL-LGPSCSWEA---EGLHCSCSSQASPAP 483
+ G + C A + GS + L V+ PP++ L PS + +C++ +P+P
Sbjct: 1948 LSDAGSYRCVASNVAGSTELRYGLRVNVPPRITLPPSLPGPVLVNTPVRLTCNATGAPSP 2007
Query: 484 SLRW 487
+L W
Sbjct: 2008 TLMW 2011
Score = 67.8 bits (164), Expect = 3e-11
Identities = 66/247 (26%), Positives = 95/247 (38%), Gaps = 36/247 (14%)
Query: 303 DRVLSSSHPWGPRTL----GLELRGVRAGDSGRYTCRAENRLGSQQQALDLSVQYPPENL 358
+R+ S + W L L L V+ GDSG Y C A N GS L VQ PP+
Sbjct: 1064 NRLALSKYVWEEYGLLPSGSLRLAQVQVGDSGHYECTASNPAGSASHRYVLGVQVPPQ-- 1121
Query: 359 RVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPPARLSWTRWGQTVGPSQPSDP 418
V R L VL G++L L CV +P +LSW++ G + P
Sbjct: 1122 ---VQPGPRV----------LKVLVGEALDLNCVAEGNPEPQLSWSKDGVVLQGRGPQ-- 1166
Query: 419 GVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSVHYPPQLLGPSCSW-----EAEGLHC 473
G + I+ G + C A + G + L V PP S E
Sbjct: 1167 GSVHFAAIRTSDAGRYRCEASNSAGVDAWEVELRVLEPPHWGADETSGLLERVAGENASL 1226
Query: 474 SCSSQASPAPSLRWWLG--EELLEGNS-----SQGSF---EVTPSSAGPWANSSLSLHGG 523
C ++ +P P + W G E L G +GS V+P+ +G + + + G
Sbjct: 1227 PCPARGTPKPQVTWRKGPSSEPLHGQPGVAVLEEGSLFLASVSPADSGDYECQATNEVGS 1286
Query: 524 LSSGLRL 530
S +L
Sbjct: 1287 TSRRAKL 1293
Score = 65.5 bits (158), Expect = 2e-10
Identities = 76/290 (26%), Positives = 113/290 (38%), Gaps = 52/290 (17%)
Query: 217 PSPQDHDTDL-TCHVDFSRKGVSAQRTVRLRVAYAPKDLIISISHDNTSALELQGNVIYL 275
P+ Q+ D TC SA+ ++L V +AP+ + + D T
Sbjct: 753 PAAQERDAGTYTCRAVNELGDASAE--IQLAVGHAPQ--LTELPRDVT------------ 796
Query: 276 EVQKGQFLRLLCAADSQPPATLSWVLQDR--------VLSSSHPWGPRTLGLELRGVRAG 327
V+ G+ L C A +PP T++W D S P + L V
Sbjct: 797 -VELGRSALLACRATGRPPPTVTWRRGDGQPLGLRLGAGRGSRSRQPDSGVLFFESVAPE 855
Query: 328 DSGRYTCRAENRLGSQQQALDLSV--QYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQ 385
D Y C A N G Q L V PP+ ++ + TV VLEGQ
Sbjct: 856 DQAPYVCEARNVFGKVQAEARLIVTGHAPPQ-----IASSAPTVR----------VLEGQ 900
Query: 386 SLRLVCVTHSSPPA-RLSWTRWGQTVGPSQPSD---PGVLELPPIQMEHEGEFTCHAQHP 441
+ L C+ + P W + G+ + P G L L EH G ++C A +
Sbjct: 901 PVSLPCIVLAGRPLPERHWLKDGRPLPPGSRHSIRADGSLHLDRALQEHAGRYSCVATNT 960
Query: 442 LGSQHVSLSLSVHYPPQLLGPSCSWEA--EGLHCS--CSSQASPAPSLRW 487
GSQH + L V PP+ + P+ + EG+ S C + PAP++ W
Sbjct: 961 AGSQHRDVELVVQVPPR-IHPTATHHITNEGVPASLPCVASGVPAPTITW 1009
Score = 65.5 bits (158), Expect = 2e-10
Identities = 58/230 (25%), Positives = 92/230 (40%), Gaps = 26/230 (11%)
Query: 275 LEVQKGQFLRLLCAADSQPPATLSWVLQDRVLS--SSHPWGPRTLGLELRGVRAGDSGRY 332
++V GQ L+C P L+W R L+ +H P + L++ +G Y
Sbjct: 2455 IKVLDGQTAHLMCNVTGHPQPKLTWFKDGRPLARGDAHHISPDGVLLQVLQANLSSAGHY 2514
Query: 333 TCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCV 392
+C A N +G + + LSV P L A+ V + N S L+C
Sbjct: 2515 SCIAANAVGEKTKHFQLSVLLAPTILGGAEDSADEEVTVTVNNPIS----------LICE 2564
Query: 393 THSSPPARLSWTRWGQTVGPSQPSD--PGV--LELPPIQMEHEGEFTCHAQHPLGSQHVS 448
+ P ++W + G S+ PG L++ Q E G++TC + LG +
Sbjct: 2565 ALAFPSPNITWMKDGAPFEASRNIQLLPGTHGLQILNAQKEDAGQYTCVVTNELGEAVKN 2624
Query: 449 LSLSVHYPPQL-----LGPSCSWEAE-----GLHCSCSSQASPAPSLRWW 488
+ V PP + LG E + L C S A P P++RW+
Sbjct: 2625 YHVEVLIPPSISKDDPLGEVGVKEVKTKVNSTLTLECESWAVPPPTIRWY 2674
Score = 65.5 bits (158), Expect = 2e-10
Identities = 71/296 (23%), Positives = 111/296 (37%), Gaps = 47/296 (15%)
Query: 275 LEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLG----LELRGVRAGDSG 330
L +G L C A P ++W + +S + G T+ L ++ + D+G
Sbjct: 4047 LSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSGAE--GKFTIQPSGELLVKNLEGQDAG 4104
Query: 331 RYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLV 390
YTC AEN +G ++ + L++ P V L SL + G L L
Sbjct: 4105 TYTCTAENAVGRARRRVHLTILVLP-------------VFTTLPGDRSLRL--GDRLWLR 4149
Query: 391 CVTHSSPPARLSWTRWGQ--TVGPSQPSDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVS 448
C SP R+ WT + T G S+ L+ + E G + C A++ +G
Sbjct: 4150 CAARGSPTPRIGWTVNDRPVTEGVSEQDGGSTLQRAAVSREDSGTYVCWAENRVGRTQAV 4209
Query: 449 LSLSVHYPPQLLGPSCSWEAE----GLHCSCSSQASPAPSLRWWLGEELLEGNSSQGSFE 504
+ V P L G + S+ E + C + P P + W L G+ + +
Sbjct: 4210 SFVHVKEAPVLQGEAFSYLVEPVGGSIQLDCVVRGDPVPDIHWIKDGLPLRGSHLRHQLQ 4269
Query: 505 VTPSSAGPWANSSLSLH-GGLSSGLRLRCKAWNVHGA---------QSGSVFQLLP 550
N SL++H R +C A N G QS VFQ+ P
Sbjct: 4270 ----------NGSLTIHRTERDDAGRYQCLAENEMGVAKKVVILVLQSAPVFQVEP 4315
Score = 65.1 bits (157), Expect = 2e-10
Identities = 73/286 (25%), Positives = 109/286 (38%), Gaps = 43/286 (15%)
Query: 277 VQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLGLELRGVRAGDSGRYTCRA 336
V G+ L+C A PP + W + + P G + L + + D+G YTCRA
Sbjct: 709 VAVGEEAVLVCEASGVPPPRVIWYRGGLEMILA-PEGSSSGKLRIPAAQERDAGTYTCRA 767
Query: 337 ENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSS 396
N LG + L+V + P+ +++ R V L G+S L C
Sbjct: 768 VNELGDASAEIQLAVGHAPQ-----LTELPRDVTVEL----------GRSALLACRATGR 812
Query: 397 PPARLSWTRW-GQTVG---------PSQPSDPGVLELPPIQMEHEGEFTCHAQHPLGSQH 446
PP ++W R GQ +G S+ D GVL + E + + C A++ G
Sbjct: 813 PPPTVTWRRGDGQPLGLRLGAGRGSRSRQPDSGVLFFESVAPEDQAPYVCEARNVFGKVQ 872
Query: 447 VSLSLSV--HYPPQLLGPSCS---WEAEGLHCSCSSQAS-PAPSLRWWLGEELLEGNS-S 499
L V H PPQ+ + + E + + C A P P W L +G
Sbjct: 873 AEARLIVTGHAPPQIASSAPTVRVLEGQPVSLPCIVLAGRPLPERHW-----LKDGRPLP 927
Query: 500 QGSFEVTPSSAGPWANSSLSLHGGLSSGLRLRCKAWNVHGAQSGSV 545
GS + + +L H G R C A N G+Q V
Sbjct: 928 PGSRHSIRADGSLHLDRALQEHAG-----RYSCVATNTAGSQHRDV 968
Score = 63.9 bits (154), Expect = 5e-10
Identities = 92/360 (25%), Positives = 141/360 (39%), Gaps = 56/360 (15%)
Query: 161 VYIPETLEPGQPVTVICVFNWAFKKC-----PAPSFSWT--GAALSPRRTRPSTSHFSVL 213
V++P T+ Q + + C PAP+ SW+ GA L R + S L
Sbjct: 3853 VHVPPTIADDQTDFTVTMMAPVVLTCHSTGIPAPTVSWSKAGAQLGARGSGYRVSPSGAL 3912
Query: 214 SFTPSPQDHDTDLTCHVDFSRKGVSAQRTVRLRVAYAPKDLIISISHDNTSALELQGNVI 273
+ H TC S GV A + V L V +P ++ +V+
Sbjct: 3913 EIGQALPIHAGRYTCSARNSA-GV-AHKHVFLTVQASP-------------VVKPLPSVV 3957
Query: 274 YLEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTL-GLELRGVRAG--DSG 330
++ L C A P T++W Q L+ + + L G +LR A D+G
Sbjct: 3958 RAVAEEEVLLP--CEASGIPRPTITW--QKEGLNVATGVSTQVLPGGQLRIAHASPEDAG 4013
Query: 331 RYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLV 390
Y C A+N GS L VQ PP V+EN L EG L
Sbjct: 4014 NYLCIAKNSAGSAMGKTRLVVQVPP-------------VIEN--GLPDLSTTEGSHAFLP 4058
Query: 391 CVTHSSPPARLSWTRWGQTVGPS------QPSDPGVLELPPIQMEHEGEFTCHAQHPLGS 444
C SP ++W + GQ V + QPS G L + ++ + G +TC A++ +G
Sbjct: 4059 CKARGSPEPNITWDKDGQPVSGAEGKFTIQPS--GELLVKNLEGQDAGTYTCTAENAVGR 4116
Query: 445 QHVSLSLSVHYPP---QLLGPSCSWEAEGLHCSCSSQASPAPSLRWWLGEE-LLEGNSSQ 500
+ L++ P L G + L C+++ SP P + W + + + EG S Q
Sbjct: 4117 ARRRVHLTILVLPVFTTLPGDRSLRLGDRLWLRCAARGSPTPRIGWTVNDRPVTEGVSEQ 4176
Score = 61.6 bits (148), Expect = 2e-09
Identities = 57/241 (23%), Positives = 95/241 (39%), Gaps = 37/241 (15%)
Query: 283 LRLLCAADSQPPATLSWVLQDRVLSSSHPWG--PRTLGLELRGVRAGDSGRYTCRAENRL 340
+ L+C A + P ++W+ +S P T GL++ + D+G+YTC N L
Sbjct: 2559 ISLICEALAFPSPNITWMKDGAPFEASRNIQLLPGTHGLQILNAQKEDAGQYTCVVTNEL 2618
Query: 341 GSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPPAR 400
G + + V PP S + L +G + +L L C + + PP
Sbjct: 2619 GEAVKNYHVEVLIPP-------SISKDDPLGEVGV-KEVKTKVNSTLTLECESWAVPPPT 2670
Query: 401 LSWTRWGQTVGPSQP----SDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSVHYP 456
+ W + GQ V PS + +L++ P Q+ G + C A + G ++ + P
Sbjct: 2671 IRWYKDGQPVTPSSRLQVLGEGRLLQIQPTQVSDSGRYLCVATNVAGEDDQDFNVLIQVP 2730
Query: 457 P--QLLGP--------SCSWEAEG-------------LHCSCSSQASPAPSLRWWLGEEL 493
P Q +G S EA G + C + A P P L W+ ++
Sbjct: 2731 PMFQKVGDFSAAFEILSREEEARGGVTEYREIVENNPAYLYCDTNAIPPPDLTWYREDQP 2790
Query: 494 L 494
L
Sbjct: 2791 L 2791
Score = 58.9 bits (141), Expect = 2e-08
Identities = 82/336 (24%), Positives = 115/336 (34%), Gaps = 97/336 (28%)
Query: 275 LEVQKGQFLRLLCAA-DSQPPATLSWVLQDRVLSSSHPWGPRTLG-LELRGVRAGDSGRY 332
+ V +GQ + L C +P W+ R L R G L L +GRY
Sbjct: 894 VRVLEGQPVSLPCIVLAGRPLPERHWLKDGRPLPPGSRHSIRADGSLHLDRALQEHAGRY 953
Query: 333 TCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCV 392
+C A N GSQ + ++L VQ PP + + T ++ N EG L CV
Sbjct: 954 SCVATNTAGSQHRDVELVVQVPP--------RIHPTATHHITN-------EGVPASLPCV 998
Query: 393 THSSPPARLSWTRWGQTV---GP------------SQPS--DPGV--------------- 420
P ++WT+ + GP +QPS D G
Sbjct: 999 ASGVPAPTITWTKETNALTSRGPHYNVSKEGTLLIAQPSAQDAGAYVCTATNTVGFSSQE 1058
Query: 421 -------------------------LELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSVHY 455
L L +Q+ G + C A +P GS L V
Sbjct: 1059 MRLSVNRLALSKYVWEEYGLLPSGSLRLAQVQVGDSGHYECTASNPAGSASHRYVLGVQV 1118
Query: 456 PPQLL-GPSC--SWEAEGLHCSCSSQASPAPSLRWWLGEELLEGNSSQGSFE---VTPSS 509
PPQ+ GP E L +C ++ +P P L W +L+G QGS + S
Sbjct: 1119 PPQVQPGPRVLKVLVGEALDLNCVAEGNPEPQLSWSKDGVVLQGRGPQGSVHFAAIRTSD 1178
Query: 510 AGPWANSSLSLHGGLSSGLRLRCKAWNVHGAQSGSV 545
AG R RC+A N G + V
Sbjct: 1179 AG-----------------RYRCEASNSAGVDAWEV 1197
Score = 57.8 bits (138), Expect = 3e-08
Identities = 58/235 (24%), Positives = 97/235 (41%), Gaps = 27/235 (11%)
Query: 277 VQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRT--LGLELRGVRAGDSGRYTC 334
V G+ L C + P L+WV RVL +S + L LE+ G+ D GRY C
Sbjct: 528 VSPGETAVLSCRVLGEAPYNLTWVRDWRVLPASTGRVAQLADLSLEISGIIPTDGGRYQC 587
Query: 335 RAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTH 394
A N G + ++ L V+ P+ V + + +S +G +++ C
Sbjct: 588 VASNANGVTRASVWLLVREAPQ---VSI------------HTSSQHFSQGVEVKVSCSAS 632
Query: 395 SSPPARLSWTRWGQTVGPS---QPSDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSL 451
P +SW+R Q + G L + + E G ++C A + +G+ +++L
Sbjct: 633 GYPTPHISWSRESQALQEDSRIHVDAQGTLIIQGVAPEDAGNYSCQATNEVGTDQETVTL 692
Query: 452 SVHYPPQLLGPSC---SWEAEGLHCSCSSQASPAPSLRWWLG--EELL--EGNSS 499
PP + + E C + P P + W+ G E +L EG+SS
Sbjct: 693 YYTDPPSVSAVNAVVLVAVGEEAVLVCEASGVPPPRVIWYRGGLEMILAPEGSSS 747
Score = 51.6 bits (122), Expect = 2e-06
Identities = 79/357 (22%), Positives = 124/357 (34%), Gaps = 58/357 (16%)
Query: 153 TALTKKPDVYIPETLEPGQPVTVICVFNWAFKKC-----PAPSFSWTG--AALSPRRTRP 205
T++ + +++ T+ G P + V A C PAP SW L PR R
Sbjct: 3661 TSVAFRVEIHTVPTIRSGPPAVNVSVNQTALLPCQADGVPAPLVSWRKDRVPLDPRSPRF 3720
Query: 206 STSHFSVLSFTPSPQDHDTDLTCHVDFSRKGVSAQRTVRL----RVAYAPKDLIISISHD 261
L P C S R +R+ +A +P +L ++
Sbjct: 3721 EILPEGSLRIQPVLAQDAGHYLCLASNSAGSDRQGRDLRVLEPPAIAPSPSNLTLTA--- 3777
Query: 262 NTSALELQGNVIYLEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTL---- 317
+T AL L C A P + W + L G L
Sbjct: 3778 HTPAL------------------LPCEASGSPKPLVVWWKDGQKLDFRLQQGAYRLLPSN 3819
Query: 318 GLELRGVRAGDSGRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGT 377
L L DS ++ C N +G + ++V PP + Q + TV
Sbjct: 3820 ALLLTAPGPQDSAQFECVVSNEVGEAHRLYQVTVHVPPT---IADDQTDFTVT------M 3870
Query: 378 SLPVLEGQSLRLVCVTHSSPPARLSWTRWGQTVGPS----QPSDPGVLELPPIQMEHEGE 433
PV+ L C + P +SW++ G +G + S G LE+ H G
Sbjct: 3871 MAPVV------LTCHSTGIPAPTVSWSKAGAQLGARGSGYRVSPSGALEIGQALPIHAGR 3924
Query: 434 FTCHAQHPLGSQHVSLSLSVHYPPQLLG-PSC--SWEAEGLHCSCSSQASPAPSLRW 487
+TC A++ G H + L+V P + PS + E + C + P P++ W
Sbjct: 3925 YTCSARNSAGVAHKHVFLTVQASPVVKPLPSVVRAVAEEEVLLPCEASGIPRPTITW 3981
Score = 50.8 bits (120), Expect = 4e-06
Identities = 51/196 (26%), Positives = 72/196 (36%), Gaps = 20/196 (10%)
Query: 268 LQGNVI-YLEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLG-LELRGVR 325
LQG YL G ++L C P + W+ L SH G L +
Sbjct: 4220 LQGEAFSYLVEPVGGSIQLDCVVRGDPVPDIHWIKDGLPLRGSHLRHQLQNGSLTIHRTE 4279
Query: 326 AGDSGRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQ 385
D+GRY C AEN +G ++ + L +Q P V Q + V G
Sbjct: 4280 RDDAGRYQCLAENEMGVAKKVVILVLQSAP------VFQV---------EPQDMTVRSGD 4324
Query: 386 SLRLVCVTHSSPPARLSWTRWGQTVGPS---QPSDPGVLELPPIQMEHEGEFTCHAQHPL 442
+ L C P + W + GQ + S + G L L ++ G + C A + L
Sbjct: 4325 DVALRCQATGEPTPTIEWLQAGQPLRASRRLRTLPDGSLWLENVETGDAGTYDCVAHNLL 4384
Query: 443 GSQHVSLSLSVHYPPQ 458
GS L V PQ
Sbjct: 4385 GSATARAFLVVRGEPQ 4400
Score = 43.9 bits (102), Expect = 5e-04
Identities = 39/141 (27%), Positives = 60/141 (42%), Gaps = 24/141 (17%)
Query: 275 LEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTL---GLELRGVRAGDSGR 331
+ V+ G + L C A +P T+ W+ + L +S RTL L L V GD+G
Sbjct: 4318 MTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRASRRL--RTLPDGSLWLENVETGDAGT 4375
Query: 332 YTCRAENRLGSQQQALDLSVQYPPE-----------NLRVMVSQANRTVLENLGNGTS-- 378
Y C A N LGS L V+ P+ + V+ N +V++ +G S
Sbjct: 4376 YDCVAHNLLGSATARAFLVVRGEPQGSWGSMTGVINGRKFGVATLNTSVMQEAHSGVSSI 4435
Query: 379 ------LPVLEGQSLRLVCVT 393
+P G +R++ VT
Sbjct: 4436 HSSIRHVPANVGPLMRVLVVT 4456
Score = 43.5 bits (101), Expect = 7e-04
Identities = 56/210 (26%), Positives = 85/210 (40%), Gaps = 33/210 (15%)
Query: 321 LRGVRAGDSGRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLP 380
LR +A + G Y C A +R G+ + + V PP L V N T
Sbjct: 484 LRASKA-EEGTYECTAVSRAGTGRAKAQIVVTDPPPQL---VPAPNVT------------ 527
Query: 381 VLEGQSLRLVCVTHSSPPARLSWTR-W----GQTVGPSQPSDPGVLELPPIQMEHEGEFT 435
V G++ L C P L+W R W T +Q +D LE+ I G +
Sbjct: 528 VSPGETAVLSCRVLGEAPYNLTWVRDWRVLPASTGRVAQLADLS-LEISGIIPTDGGRYQ 586
Query: 436 CHAQHPLGSQHVSLSLSVHYPPQL-LGPSCSWEAEGLH--CSCSSQASPAPSLRWWLGEE 492
C A + G S+ L V PQ+ + S ++G+ SCS+ P P + W +
Sbjct: 587 CVASNANGVTRASVWLLVREAPQVSIHTSSQHFSQGVEVKVSCSASGYPTPHISWSRESQ 646
Query: 493 LLEGNS-----SQGSF---EVTPSSAGPWA 514
L+ +S +QG+ V P AG ++
Sbjct: 647 ALQEDSRIHVDAQGTLIIQGVAPEDAGNYS 676
>gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 3783
Score = 92.4 bits (228), Expect = 1e-18
Identities = 88/326 (26%), Positives = 135/326 (41%), Gaps = 44/326 (13%)
Query: 169 PGQPVTVICVFNWAFKKCPAPSFSWTGAALSPRRTRPSTSHFSVLSFTPSP-QDHDTDLT 227
PG+ VT++C + P SW L ++ + H S + S Q D +
Sbjct: 2045 PGELVTMVC----PVRGSPPIHVSWLKDGLPLPLSQRTLLHGSGHTLRISKVQLADAGIF 2100
Query: 228 CHVDFSRKGVSAQRTVRLRVAYAPKDLIISISHDNTSALELQGNVIYLEVQKGQFLRLLC 287
V S GV A R L+V P +E Q +V+ V +G + L C
Sbjct: 2101 TCVAASPAGV-ADRNFTLQVQVPPV----------LEPVEFQNDVV---VVRGSLVELPC 2146
Query: 288 AADSQPPATLSWVLQ-DRVLSSSHPWGPRTLGLELRGVRAGDSGRYTCRAENRLGSQQQA 346
A P +SW+ + +LS S GP L+L V AGDSG Y+C A + G ++
Sbjct: 2147 EARGVPLPLVSWMKDGEPLLSQSLEQGP---SLQLEAVGAGDSGTYSCVAVSEAGEARRH 2203
Query: 347 LDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPPARLSWTRW 406
L+V PP +E+ G T L + G + L+C +P ++W +
Sbjct: 2204 FQLTVMEPPH-------------IEDSGQPTELSLTPGAPMELLCDAQGTPQPNITWHKD 2250
Query: 407 GQTVGPSQPSDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSVHYPPQLLGPSCSW 466
GQ + + + L ++ G +TC A+ P G+ S + V PP ++GP
Sbjct: 2251 GQALTRLENNSRATRVL---RVRDAGLYTCLAESPAGAIEKSFRVRVQAPPNIVGPRGPR 2307
Query: 467 EAEGLH-----CSCSSQASPAPSLRW 487
GL CS +A PAP + W
Sbjct: 2308 FVVGLAPGQLVLECSVEAEPAPKITW 2333
Score = 87.4 bits (215), Expect = 4e-17
Identities = 108/429 (25%), Positives = 171/429 (39%), Gaps = 73/429 (17%)
Query: 111 KGSCSLVIRDAQREDEAWYFFRVER--GSRVRHSFLSNAFFLKVTALTKKPDVYIPETLE 168
+G L I++AQ D+ Y +V G VR L+ ++V + P ET+
Sbjct: 1801 RGGQRLEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLT----VQVPPTFENPKT---ETVS 1853
Query: 169 P--GQPVTVICVFNWAFKKCPAPSFSWTGAALSPRRTRPSTSHFSVLS-------FTPSP 219
G P+ + C + PAP+ +W L R S++ V+S P
Sbjct: 1854 QVAGSPLVLTCDVSGV----PAPTVTW----LKDRMPVESSAVHGVVSRGGRLQLSRLQP 1905
Query: 220 QDHDTDLTCHVDFSRKGVSAQRTVRLRVAYAPKDLIISISHDNTSALELQGNVIYLEVQK 279
T TC + ++ A++ + V AP+ ++ ++ V +
Sbjct: 1906 AQAGT-YTCVAENTQ--AEARKDFVVAVLVAPRIRSSGVAREH-------------HVLE 1949
Query: 280 GQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTL------GLELRGVRAGDSGRYT 333
GQ +RL C AD QPP ++W+ L GP L L+G+RA D+G YT
Sbjct: 1950 GQEVRLDCEADGQPPPDVAWLKDGSPLGQD--MGPHLRFYLDGGSLVLKGLRASDAGAYT 2007
Query: 334 CRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVT 393
C A N G + ++V PP T+ + +L G+ + +VC
Sbjct: 2008 CVAHNPAGEDARLHTVNVLVPP------------TIKQGADGSGTLVSRPGELVTMVCPV 2055
Query: 394 HSSPPARLSWTRWGQTVGPSQPS----DPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSL 449
SPP +SW + G + SQ + L + +Q+ G FTC A P G +
Sbjct: 2056 RGSPPIHVSWLKDGLPLPLSQRTLLHGSGHTLRISKVQLADAGIFTCVAASPAGVADRNF 2115
Query: 450 SLSVHYPPQLLGPSCSWEAEGLHCS-----CSSQASPAPSLRWWL-GEELLEGNSSQG-S 502
+L V PP L + + S C ++ P P + W GE LL + QG S
Sbjct: 2116 TLQVQVPPVLEPVEFQNDVVVVRGSLVELPCEARGVPLPLVSWMKDGEPLLSQSLEQGPS 2175
Query: 503 FEVTPSSAG 511
++ AG
Sbjct: 2176 LQLEAVGAG 2184
Score = 83.6 bits (205), Expect = 6e-16
Identities = 63/224 (28%), Positives = 95/224 (42%), Gaps = 27/224 (12%)
Query: 277 VQKGQFLRLLCAADSQPPATLSWVLQDRVLSSS----HPWGPRTLGLELRGVRAGDSGRY 332
V + ++LLC A P ++W +L +S + G R L +L ++ D+G Y
Sbjct: 232 VMEDHLVQLLCEARGVPTPNITWFKDGALLPTSTKVVYTRGGRQL--QLGRAQSSDAGVY 289
Query: 333 TCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCV 392
TC+A N +G+ ++A L V PP T+ G + + G+ + L CV
Sbjct: 290 TCKASNAVGAAEKATRLDVYVPP------------TIEGAGGRPYVVKAVAGRPVALECV 337
Query: 393 THSSPPARLSWTRWGQTVGPSQPS----DPGVLELPPIQMEHEGEFTCHAQHPLGSQHVS 448
P LSW G V S S D VL L G ++C A P G +
Sbjct: 338 ARGHPSPTLSWHHEGLPVAESNESRLETDGSVLRLESPGEASSGLYSCVASSPAGEAVLQ 397
Query: 449 LSLSVHYPPQL-----LGPSCSWEAEGLHCSCSSQASPAPSLRW 487
S+ V PPQL LG + + L C + SP P+++W
Sbjct: 398 YSVEVQVPPQLLVAEGLGQVTTIVGQPLELPCQASGSPVPTIQW 441
Score = 81.6 bits (200), Expect = 2e-15
Identities = 69/242 (28%), Positives = 98/242 (40%), Gaps = 40/242 (16%)
Query: 280 GQFLRLLCAADSQPPATLSWVLQDRVLSSSHPW-------------GPRTL----GLELR 322
GQ L L C A+ P + W+ +++ W G R L L
Sbjct: 33 GQSLTLECDANGFPVPEIVWLKDAQLVGVPLGWAGYGWDLGWGQVGGHRLLDEGQSLHFP 92
Query: 323 GVRAGDSGRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVL 382
++ GDSG Y+CRAEN+ G+ Q+ L V PP L +Q E LG L
Sbjct: 93 RIQEGDSGLYSCRAENQAGTAQRDFHLLVLTPPSVLGAGAAQ------EVLG-------L 139
Query: 383 EGQSLRLVCVTHSSPPARLSWTRWGQTVGPSQP-----SDPGVLELPPIQMEHEGEFTCH 437
G + L C T P ++ WT+ Q V P P D VL + + EG + C
Sbjct: 140 AGADVELQCWTSGVPTPQVEWTKDRQPVLPGGPHLQVQEDGQVLRITGSHVGDEGRYQCV 199
Query: 438 AQHPLGSQHVSLSLSVHYPPQLLGPSCSWEAEGL-----HCSCSSQASPAPSLRWWLGEE 492
A P G Q L VH PP + G + + E + C ++ P P++ W+
Sbjct: 200 AFSPAGQQARDFQLRVHAPPTIWGSNETGEVAVMEDHLVQLLCEARGVPTPNITWFKDGA 259
Query: 493 LL 494
LL
Sbjct: 260 LL 261
Score = 79.0 bits (193), Expect = 1e-14
Identities = 67/227 (29%), Positives = 88/227 (38%), Gaps = 35/227 (15%)
Query: 285 LLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLGLELRGVRA-----GDSGRYTCRAENR 339
L C A PP +SW + +SS W T+ ++ R +R D+G Y C A N
Sbjct: 623 LECLASGVPPPDVSWFKGHQPVSS---WMGVTVSVDGRVLRIEQAQLSDAGSYRCVASNV 679
Query: 340 LGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPPA 399
GS + L V PP R L G PVL +RL C +P
Sbjct: 680 AGSTELRYGLRVNVPP-----------RITLPPSLPG---PVLVNTPVRLTCNATGAPSP 725
Query: 400 RLSWTRWGQTVGPSQPSDPG--------VLELPPIQMEHEGEFTCHAQHPLGSQHVSLSL 451
L W + G V P+ PG VL L + G ++C A +G + L
Sbjct: 726 TLMWLKDGNPVSPA--GTPGLQVFPGGRVLTLASARASDSGRYSCVAVSAVGEDRQDVVL 783
Query: 452 SVHYPPQLLGPSCSWEA---EGLHCSCSSQASPAPSLRWWLGEELLE 495
VH PP +LG + E + C S A P P L WW LE
Sbjct: 784 QVHMPPSILGEELNVSVVANESVALECQSHAMPPPVLSWWKDGRPLE 830
Score = 79.0 bits (193), Expect = 1e-14
Identities = 64/233 (27%), Positives = 98/233 (42%), Gaps = 30/233 (12%)
Query: 270 GNVIYLEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSS---HPWGPRTLGLELRGVRA 326
G + + V + + L C + + PP LSW R L H + L L++
Sbjct: 793 GEELNVSVVANESVALECQSHAMPPPVLSWWKDGRPLEPRPGVHLSADKAL-LQVDRADV 851
Query: 327 GDSGRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQS 386
D+G YTC A N+ G ++ +L+V P + L +L V EG
Sbjct: 852 WDAGHYTCEALNQAGHSEKHYNLNVWVAP--------------VFPLRESHTLTVREGHP 897
Query: 387 LRLVCVTHSSPPARLSWTRWGQTV-----GPSQPSDPG-VLELPPIQMEHEGEFTCHAQH 440
RL C P ++SW + GQ + G S G +L L Q+ EG +TC +
Sbjct: 898 TRLSCECRGVPFPKISWRKDGQPLPGEGAGLQHVSAVGRLLYLGQAQLAQEGTYTCECSN 957
Query: 441 PLGSQHVSLSLSVHYPPQLLGP-----SCSWEAEGL-HCSCSSQASPAPSLRW 487
+G+ L L VH PPQ+ GP S +G+ C++ P P++ W
Sbjct: 958 VVGNSSQDLQLEVHVPPQIAGPREPPTQVSVVQDGVATLECNATGKPPPTVTW 1010
Score = 79.0 bits (193), Expect = 1e-14
Identities = 96/378 (25%), Positives = 158/378 (41%), Gaps = 47/378 (12%)
Query: 136 GSRVRHSFLSNAFFLKVTALTKKPDVYIPE-TLEPGQPVTVICVFNWAFKKCPAPSFSWT 194
G + +H LS L T L D E T+ P+++IC AF P+P+ +W
Sbjct: 1241 GEKTKHFQLS--VLLAPTILGGAEDSADEEVTVTVNNPISLICEA-LAF---PSPNITWM 1294
Query: 195 --GAALSPRRT---RPSTSHFSVLSFTPSPQDHDTDLTCHVDFSRKGVSAQRTVRLRVAY 249
GA R P T +L+ + ++ TC V + + A + + V
Sbjct: 1295 KDGAPFEASRNIQLLPGTHGLQILN---AQKEDAGQYTCVV--TNELGEAVKNYHVEVLI 1349
Query: 250 APKDLIISISHDNTSALELQGNVIYLEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSS 309
P SIS D+ A + V ++ + L L C + + PP T+ W + ++ S
Sbjct: 1350 PP-----SISKDDPLA---EVGVKEVKTKVNSTLTLECESWAVPPPTIRWYKDGQPVTPS 1401
Query: 310 HPWGPRTLG----LELRGVRAGDSGRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQA 365
+ LG L+++ + DSGRY C A N G Q ++ +Q PP +V A
Sbjct: 1402 SRL--QVLGEGRLLQIQPTQVSDSGRYLCVATNVAGEDDQDFNVLIQVPPMFQKVGDFSA 1459
Query: 366 NRTVL----ENLGNGTSL-PVLEGQSLRLVCVTHSSPPARLSWTRWGQTVGP----SQPS 416
+L E G T ++E L C T++ PP L+W R Q + S
Sbjct: 1460 AFEILSREEEARGGVTEYREIVENNPAYLYCDTNAIPPPDLTWYREDQPLSAGDEVSVLQ 1519
Query: 417 DPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSVHYPPQLLGPSCSWEAE------- 469
VL++P ++ E+ G ++C A + +G + L V PP +LG + E
Sbjct: 1520 GGRVLQIPLVRAENAGRYSCKASNEVGEDWLHYELLVLTPPVILGDTEELVEEVTVNASS 1579
Query: 470 GLHCSCSSQASPAPSLRW 487
+ C + +P P++ W
Sbjct: 1580 TVSLQCPALGNPVPTISW 1597
Score = 76.6 bits (187), Expect = 7e-14
Identities = 62/229 (27%), Positives = 95/229 (41%), Gaps = 27/229 (11%)
Query: 283 LRLLCAADSQPPATLSWVLQDRVLSSSHPWG----PRTLGLELRGVRAGDSGRYTCRAEN 338
+RL C A P TL W+ +S + G P L L RA DSGRY+C A +
Sbjct: 713 VRLTCNATGAPSPTLMWLKDGNPVSPAGTPGLQVFPGGRVLTLASARASDSGRYSCVAVS 772
Query: 339 RLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPP 398
+G +Q + L V PP LG ++ V+ +S+ L C +H+ PP
Sbjct: 773 AVGEDRQDVVLQVHMPP---------------SILGEELNVSVVANESVALECQSHAMPP 817
Query: 399 ARLSWTRWGQTVGPSQ----PSDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSVH 454
LSW + G+ + P +D +L++ + G +TC A + G +L+V
Sbjct: 818 PVLSWWKDGRPLEPRPGVHLSADKALLQVDRADVWDAGHYTCEALNQAGHSEKHYNLNVW 877
Query: 455 YPPQL-LGPSCSW---EAEGLHCSCSSQASPAPSLRWWLGEELLEGNSS 499
P L S + E SC + P P + W + L G +
Sbjct: 878 VAPVFPLRESHTLTVREGHPTRLSCECRGVPFPKISWRKDGQPLPGEGA 926
Score = 72.4 bits (176), Expect = 1e-12
Identities = 65/233 (27%), Positives = 92/233 (39%), Gaps = 28/233 (12%)
Query: 275 LEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSS-----HPWGPRTLGLELRGVRAGDS 329
L V++G RL C P +SW + L H L L L +
Sbjct: 890 LTVREGHPTRLSCECRGVPFPKISWRKDGQPLPGEGAGLQHVSAVGRL-LYLGQAQLAQE 948
Query: 330 GRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRL 389
G YTC N +G+ Q L L V PP+ + T + V++ L
Sbjct: 949 GTYTCECSNVVGNSSQDLQLEVHVPPQ------------IAGPREPPTQVSVVQDGVATL 996
Query: 390 VCVTHSSPPARLSWTRWGQTVGPS---QPSDPG-VLELPPIQMEHEGEFTCHAQHPLGSQ 445
C PP ++W R GQ VG Q + G L + Q H G ++C A++ G
Sbjct: 997 ECNATGKPPPTVTWERDGQPVGAELGLQLQNQGQSLHVERAQAAHTGRYSCVAENLAGRA 1056
Query: 446 HVSLSLSVHYPPQLLG---PSCSWEA---EGLHCSCSSQASPAPSLRWWLGEE 492
LSV PP+L+G P + A L C + P P++RW+ GEE
Sbjct: 1057 ERKFELSVLVPPELIGDLDPLTNITAALHSPLTLLCEAMGIPPPAIRWFRGEE 1109
Score = 72.4 bits (176), Expect = 1e-12
Identities = 90/370 (24%), Positives = 142/370 (38%), Gaps = 45/370 (12%)
Query: 149 FLKVTALTKKPDVYIPETLEPGQPVTVICVFNWAFKKCPA-----PSFSW--TGAALSPR 201
+L L P V + +T E + VTV + + CPA P+ SW G SP
Sbjct: 1549 WLHYELLVLTPPVILGDTEELVEEVTVNASSTVSLQ-CPALGNPVPTISWLQNGLPFSPS 1607
Query: 202 RTRPSTSHFSVLSFTPSPQDHDTDLTCHVDFSRKGVSAQRTVRLRVAYAPKDLIISISHD 261
VL + + C + + SA++ LRV P+ I + +
Sbjct: 1608 PRLQVLEDGQVLQVSTAEVADAASYMCVAE--NQAGSAEKLFTLRVQVPPR--IAGLDLE 1663
Query: 262 NTSALELQGNVIYLEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWG--PRTLGL 319
+A+ L +V L C + P ++W + LS P T L
Sbjct: 1664 QVTAI-LNSSV-----------SLPCDVHAHPNPEVTWYKDSQALSLGEEVFLLPGTHTL 1711
Query: 320 ELRGVRAGDSGRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSL 379
+L R DSG YTC A N G Q+ + LSV PP QA R G ++
Sbjct: 1712 QLGRARLSDSGMYTCEALNAAGRDQKLVQLSVLVPP-----AFRQAPR------GPQDAV 1760
Query: 380 PVLEGQSLRLVCVTHSSPPARLSWTRWGQTVGPSQPSDP----GVLELPPIQMEHEGEFT 435
V G L C T + P ++W + GQ + +Q + LE+ Q+ +G ++
Sbjct: 1761 LVRVGDKAVLSCETDALPEPTVTWYKDGQPLVLAQRTQALRGGQRLEIQEAQVSDKGLYS 1820
Query: 436 CHAQHPLGSQHVSLSLSVHYPPQLLGPSCSWEAE----GLHCSCSSQASPAPSLRWWLGE 491
C + G + +L+V PP P ++ L +C PAP++ W
Sbjct: 1821 CKVSNVAGEAVRTFTLTVQVPPTFENPKTETVSQVAGSPLVLTCDVSGVPAPTVTWLKDR 1880
Query: 492 ELLEGNSSQG 501
+E ++ G
Sbjct: 1881 MPVESSAVHG 1890
Score = 72.4 bits (176), Expect = 1e-12
Identities = 83/355 (23%), Positives = 138/355 (38%), Gaps = 50/355 (14%)
Query: 166 TLEPGQPVTVICVFNWAFKKCPAPSFSWTGAALSPRRTRPSTSHFSVLSFTPSPQDHDTD 225
+L PG P+ ++C + P P+ +W + R ++ VL D
Sbjct: 2224 SLTPGAPMELLC----DAQGTPQPNITWHKDGQALTRLENNSRATRVLRV------RDAG 2273
Query: 226 LTCHVDFSRKGVSAQRTVRLRVAYAPKDLIISISHDNTSALELQGNVIYLEVQKGQFLRL 285
L + S G + +++ R+RV P + + +G + + GQ + L
Sbjct: 2274 LYTCLAESPAG-AIEKSFRVRVQAPP------------NIVGPRGPRFVVGLAPGQLV-L 2319
Query: 286 LCAADSQPPATLSWVLQDRVLSS-SHPWGP-RTLGLELRGVRAGDSGRYTCRAENRLGSQ 343
C+ +++P ++W VL +H P R L+L+ + DSG Y+C A N GS
Sbjct: 2320 ECSVEAEPAPKITWHRDGIVLQEDAHTQFPERGRFLQLQALSTADSGDYSCTARNAAGST 2379
Query: 344 QQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPPARLSW 403
A + + P +R N +V Q+ L C P +SW
Sbjct: 2380 SVAFRVEIHTVP-TIRSGPPAVNVSV--------------NQTALLPCQADGVPAPLVSW 2424
Query: 404 TRWGQTVGPSQPS----DPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSVHYPPQL 459
+ + P P G L + P+ + G + C A + GS L V PP
Sbjct: 2425 RKDRVPLDPRSPRFEILPEGSLRIQPVLAQDAGHYLCLASNSAGSDRQGRDLRVLEPP-A 2483
Query: 460 LGPSCSWEAEGLH----CSCSSQASPAPSLRWWLGEELLEGNSSQGSFEVTPSSA 510
+ PS S H C + SP P + WW + L+ QG++ + PS+A
Sbjct: 2484 IAPSPSNLTLTAHTPALLPCEASGSPKPLVVWWKDGQKLDFRLQQGAYRLLPSNA 2538
Score = 71.2 bits (173), Expect = 3e-12
Identities = 54/226 (23%), Positives = 94/226 (41%), Gaps = 24/226 (10%)
Query: 285 LLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLG--LELRGVRAGDSGRYTCRAENRLGS 342
L C A +PP T++W + + + + G L + +A +GRY+C AEN G
Sbjct: 996 LECNATGKPPPTVTWERDGQPVGAELGLQLQNQGQSLHVERAQAAHTGRYSCVAENLAGR 1055
Query: 343 QQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPPARLS 402
++ +LSV PPE ++ +L T++ L L+C PP +
Sbjct: 1056 AERKFELSVLVPPE------------LIGDLDPLTNITAALHSPLTLLCEAMGIPPPAIR 1103
Query: 403 WTRWGQTVGPSQP----SDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSVHYPPQ 458
W R + V P + + +L++ Q + G ++C A + G + S+ V PP
Sbjct: 1104 WFRGEEPVSPGEDTYLLAGGWMLKMTQTQEQDSGLYSCLASNEAGEARRNFSVEVLVPPS 1163
Query: 459 LLGPSCS-----WEAEGLHCSCSSQASPAPSLRWWL-GEELLEGNS 498
+ + + H C+ P P L W+ G L G++
Sbjct: 1164 IENEDLEEVIKVLDGQTAHLMCNVTGHPQPKLTWFKDGRPLARGDA 1209
Score = 70.9 bits (172), Expect = 4e-12
Identities = 103/416 (24%), Positives = 160/416 (38%), Gaps = 75/416 (18%)
Query: 160 DVYIPETLE------------PGQPVTVICVFNWAFKKCPAPSFSWTGAALSPRRTRPST 207
DVY+P T+E G+PV + CV + P+P+ SW L + S
Sbjct: 307 DVYVPPTIEGAGGRPYVVKAVAGRPVALECVA----RGHPSPTLSWHHEGLPVAESNESR 362
Query: 208 --SHFSVLSFTPSPQDHDTDLTCHVDFSRKGVSA-QRTVRLRVAYAPKDLIISISHDNTS 264
+ SVL SP + + L V S G + Q +V ++V P L+++
Sbjct: 363 LETDGSVLRLE-SPGEASSGLYSCVASSPAGEAVLQYSVEVQV---PPQLLVA------- 411
Query: 265 ALELQGNVIYLEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLG--LELR 322
E G V + GQ L L C A P T+ W+ R + G L +
Sbjct: 412 --EGLGQVTTIV---GQPLELPCQASGSPVPTIQWLQNGRPAEELAGVQVASQGTTLHID 466
Query: 323 GVRAGDSGRYTCRAENRLGSQQQALDLSV--QYPPENLRVMVSQANRTVLENLGNGTSLP 380
V SG + C+A N G+ +++SV ++ P L V + Q + + +S P
Sbjct: 467 HVELDHSGLFACQATNEAGTAGAEVEVSVHGEWAPGVLEVPIGQYHW----GXEHHSSFP 522
Query: 381 VLEGQSLRLVCVTHSSPPARLSW----TRWGQTVG-PSQPSDPGVLELPPIQMEHEGEFT 435
+ H PP W + WG+ G P S P L++ + + EG +T
Sbjct: 523 AACDPPVHRGWGAHPKPPLVEGWCSPGSLWGEPTGIPVAYSLPPPLQIEKVDLRDEGIYT 582
Query: 436 CHAQHPLGSQHVSLSLSVHYPPQL-LGP--SCSWEAEGLHCSCSSQASPAPSLRWWLGEE 492
C A + G ++L V PP + GP E + C + P P + W+ G +
Sbjct: 583 CAATNLAGESKREVALKVLVPPNIEPGPVNKAVLENASVTLECLASGVPPPDVSWFKGHQ 642
Query: 493 LLEGNSSQGSFEVTPSSAGPWANSSLSLHG--------GLSSGLRLRCKAWNVHGA 540
P S+ W ++S+ G LS RC A NV G+
Sbjct: 643 --------------PVSS--WMGVTVSVDGRVLRIEQAQLSDAGSYRCVASNVAGS 682
Score = 69.3 bits (168), Expect = 1e-11
Identities = 77/289 (26%), Positives = 109/289 (37%), Gaps = 46/289 (15%)
Query: 275 LEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTL--------GLELRGVRA 326
+ V Q L C AD P +SW +DRV P PR+ L ++ V A
Sbjct: 2400 VNVSVNQTALLPCQADGVPAPLVSW-RKDRV-----PLDPRSPRFEILPEGSLRIQPVLA 2453
Query: 327 GDSGRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQS 386
D+G Y C A N GS +Q DL V PP + S +N T+ + P L
Sbjct: 2454 QDAGHYLCLASNSAGSDRQGRDLRVLEPP---AIAPSPSNLTLTAH------TPAL---- 2500
Query: 387 LRLVCVTHSSPPARLSWTRWGQTV------GPSQPSDPGVLELPPIQMEHEGEFTCHAQH 440
L C SP + W + GQ + G + L L + +F C +
Sbjct: 2501 --LPCEASGSPKPLVVWWKDGQKLDFRLQQGAYRLLPSNALLLTAPGPQDSAQFECVVSN 2558
Query: 441 PLGSQHVSLSLSVHYPPQLLGPSCSWEAEGLH---CSCSSQASPAPSLRWWLGEELLEGN 497
+G H ++VH PP + + + +C S PAP++ W L
Sbjct: 2559 EVGEAHRLYQVTVHVPPTIADDQTDFTVTMMAPVVLTCHSTGIPAPTVSWSKAGAQLGAR 2618
Query: 498 SSQGSFEVTPSSAGPWANSSLSLHGGLSSGLRLRCKAWNVHGAQSGSVF 546
S + V+PS A +L +H G R C A N G VF
Sbjct: 2619 GS--GYRVSPSGALE-IGQALPIHAG-----RYTCSARNSAGVAHKHVF 2659
Score = 68.9 bits (167), Expect = 1e-11
Identities = 100/424 (23%), Positives = 151/424 (35%), Gaps = 65/424 (15%)
Query: 83 GAPVATNNQSREVEMSTRDRFQLTGDPGKGSCSLVIRDAQREDEAWYFFRVERGSRVRHS 142
G PVA +N+SR + R + G+ G S V E Y V+ V
Sbjct: 352 GLPVAESNESRLETDGSVLRLESPGEASSGLYSCVASSPAGEAVLQYSVEVQ----VPPQ 407
Query: 143 FLSNAFFLKVTALTKKPDVYIPETLEPGQPVTVICVFNWAFKKCPAPSFSWTGAALSPRR 202
L +VT + +P + +P G PV I W PA + G ++ +
Sbjct: 408 LLVAEGLGQVTTIVGQP-LELP-CQASGSPVPTI---QWLQNGRPAEELA--GVQVASQG 460
Query: 203 TRPSTSHFSVLSFTPSPQDHDTDLTCHVDFSRKGVSAQRTVRLRVAYAPKDLIISISHDN 262
T H + DH C A+ V + +AP L + I +
Sbjct: 461 TTLHIDHVEL--------DHSGLFACQATNEAGTAGAEVEVSVHGEWAPGVLEVPIGQYH 512
Query: 263 TSALELQGNVIYLE--VQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRT---- 316
+ V +G A +PP W S WG T
Sbjct: 513 WGXEHHSSFPAACDPPVHRGW------GAHPKPPLVEGWC------SPGSLWGEPTGIPV 560
Query: 317 -----LGLELRGVRAGDSGRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLE 371
L++ V D G YTC A N G ++ + L V PP + N+ VLE
Sbjct: 561 AYSLPPPLQIEKVDLRDEGIYTCAATNLAGESKREVALKVLVPP---NIEPGPVNKAVLE 617
Query: 372 NLGNGTSLPVLEGQSLRLVCVTHSSPPARLSWTRWGQTV----GPSQPSDPGVLELPPIQ 427
N S+ L C+ PP +SW + Q V G + D VL + Q
Sbjct: 618 N------------ASVTLECLASGVPPPDVSWFKGHQPVSSWMGVTVSVDGRVLRIEQAQ 665
Query: 428 MEHEGEFTCHAQHPLGSQHVSLSLSVHYPPQL-LGPSCSWEA---EGLHCSCSSQASPAP 483
+ G + C A + GS + L V+ PP++ L PS + +C++ +P+P
Sbjct: 666 LSDAGSYRCVASNVAGSTELRYGLRVNVPPRITLPPSLPGPVLVNTPVRLTCNATGAPSP 725
Query: 484 SLRW 487
+L W
Sbjct: 726 TLMW 729
Score = 64.7 bits (156), Expect = 3e-10
Identities = 56/230 (24%), Positives = 89/230 (38%), Gaps = 26/230 (11%)
Query: 275 LEVQKGQFLRLLCAADSQPPATLSWVLQDRVLS--SSHPWGPRTLGLELRGVRAGDSGRY 332
++V GQ L+C P L+W R L+ +H P + L++ +G Y
Sbjct: 1173 IKVLDGQTAHLMCNVTGHPQPKLTWFKDGRPLARGDAHHISPDGVLLQVLQANLSSAGHY 1232
Query: 333 TCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCV 392
+C A N +G + + LSV P L A+ V + N S L+C
Sbjct: 1233 SCIAANAVGEKTKHFQLSVLLAPTILGGAEDSADEEVTVTVNNPIS----------LICE 1282
Query: 393 THSSPPARLSWTRWGQTVGPSQPSD--PGV--LELPPIQMEHEGEFTCHAQHPLGSQHVS 448
+ P ++W + G S+ PG L++ Q E G++TC + LG +
Sbjct: 1283 ALAFPSPNITWMKDGAPFEASRNIQLLPGTHGLQILNAQKEDAGQYTCVVTNELGEAVKN 1342
Query: 449 LSLSVHYPPQLLGPSCSWEA----------EGLHCSCSSQASPAPSLRWW 488
+ V PP + E L C S A P P++RW+
Sbjct: 1343 YHVEVLIPPSISKDDPLAEVGVKEVKTKVNSTLTLECESWAVPPPTIRWY 1392
Score = 63.9 bits (154), Expect = 5e-10
Identities = 92/360 (25%), Positives = 141/360 (39%), Gaps = 56/360 (15%)
Query: 161 VYIPETLEPGQPVTVICVFNWAFKKC-----PAPSFSWT--GAALSPRRTRPSTSHFSVL 213
V++P T+ Q + + C PAP+ SW+ GA L R + S L
Sbjct: 2571 VHVPPTIADDQTDFTVTMMAPVVLTCHSTGIPAPTVSWSKAGAQLGARGSGYRVSPSGAL 2630
Query: 214 SFTPSPQDHDTDLTCHVDFSRKGVSAQRTVRLRVAYAPKDLIISISHDNTSALELQGNVI 273
+ H TC S GV A + V L V +P ++ +V+
Sbjct: 2631 EIGQALPIHAGRYTCSARNSA-GV-AHKHVFLTVQASP-------------VVKPLPSVV 2675
Query: 274 YLEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTL-GLELRGVRAG--DSG 330
++ L C A P T++W Q L+ + + L G +LR A D+G
Sbjct: 2676 RAVAEEEVLLP--CEASGIPRPTITW--QKEGLNVATGVSTQVLPGGQLRIAHASPEDAG 2731
Query: 331 RYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLV 390
Y C A+N GS L VQ PP V+EN L EG L
Sbjct: 2732 NYLCIAKNSAGSAMGKTRLVVQVPP-------------VIEN--GLPDLSTTEGSHAFLP 2776
Query: 391 CVTHSSPPARLSWTRWGQTVGPS------QPSDPGVLELPPIQMEHEGEFTCHAQHPLGS 444
C SP ++W + GQ V + QPS G L + ++ + G +TC A++ +G
Sbjct: 2777 CKARGSPEPNITWDKDGQPVSGAEGKFTIQPS--GELLVKNLEGQDAGTYTCTAENAVGR 2834
Query: 445 QHVSLSLSVHYPP---QLLGPSCSWEAEGLHCSCSSQASPAPSLRWWLGEE-LLEGNSSQ 500
+ L++ P L G + L C+++ SP P + W + + + EG S Q
Sbjct: 2835 ARRRVHLTILVLPVFTTLPGDRSLRLGDRLWLRCAARGSPTPRIGWTVNDRPVTEGVSEQ 2894
Score = 63.2 bits (152), Expect = 8e-10
Identities = 54/223 (24%), Positives = 87/223 (39%), Gaps = 27/223 (12%)
Query: 275 LEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLG----LELRGVRAGDSG 330
L +G L C A P ++W + +S + G T+ L ++ + D+G
Sbjct: 2765 LSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSGAE--GKFTIQPSGELLVKNLEGQDAG 2822
Query: 331 RYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLV 390
YTC AEN +G ++ + L++ P V L SL + G L L
Sbjct: 2823 TYTCTAENAVGRARRRVHLTILVLP-------------VFTTLPGDRSLRL--GDRLWLR 2867
Query: 391 CVTHSSPPARLSWTRWGQ--TVGPSQPSDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVS 448
C SP R+ WT + T G S+ L+ + E G + C A++ +G
Sbjct: 2868 CAARGSPTPRIGWTVNDRPVTEGVSEQDGGSTLQRAAVSREDSGTYVCWAENRVGRTQAV 2927
Query: 449 LSLSVHYPPQLLGPSCSWEAE----GLHCSCSSQASPAPSLRW 487
+ V P L G + S+ E + C + P P + W
Sbjct: 2928 SFVHVKEAPVLQGEAFSYLVEPVGGSIQLDCVVRGDPVPDIHW 2970
Score = 62.0 bits (149), Expect = 2e-09
Identities = 57/241 (23%), Positives = 95/241 (39%), Gaps = 37/241 (15%)
Query: 283 LRLLCAADSQPPATLSWVLQDRVLSSSHPWG--PRTLGLELRGVRAGDSGRYTCRAENRL 340
+ L+C A + P ++W+ +S P T GL++ + D+G+YTC N L
Sbjct: 1277 ISLICEALAFPSPNITWMKDGAPFEASRNIQLLPGTHGLQILNAQKEDAGQYTCVVTNEL 1336
Query: 341 GSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPPAR 400
G + + V PP S + L +G + +L L C + + PP
Sbjct: 1337 GEAVKNYHVEVLIPP-------SISKDDPLAEVGV-KEVKTKVNSTLTLECESWAVPPPT 1388
Query: 401 LSWTRWGQTVGPSQP----SDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSVHYP 456
+ W + GQ V PS + +L++ P Q+ G + C A + G ++ + P
Sbjct: 1389 IRWYKDGQPVTPSSRLQVLGEGRLLQIQPTQVSDSGRYLCVATNVAGEDDQDFNVLIQVP 1448
Query: 457 P--QLLGP--------SCSWEAEG-------------LHCSCSSQASPAPSLRWWLGEEL 493
P Q +G S EA G + C + A P P L W+ ++
Sbjct: 1449 PMFQKVGDFSAAFEILSREEEARGGVTEYREIVENNPAYLYCDTNAIPPPDLTWYREDQP 1508
Query: 494 L 494
L
Sbjct: 1509 L 1509
Score = 52.8 bits (125), Expect = 1e-06
Identities = 52/196 (26%), Positives = 73/196 (37%), Gaps = 20/196 (10%)
Query: 268 LQGNVI-YLEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLG-LELRGVR 325
LQG YL G ++L C P + W+ L SH G L +R
Sbjct: 2938 LQGEAFSYLVEPVGGSIQLDCVVRGDPVPDIHWIKDGLPLRGSHLRHQLQNGSLTIRRTE 2997
Query: 326 AGDSGRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQ 385
D+GRY C AEN +G ++ + L +Q P V Q + V G
Sbjct: 2998 RDDAGRYQCLAENEMGVAKKVVILVLQSAP------VFQV---------EPQDMTVRSGD 3042
Query: 386 SLRLVCVTHSSPPARLSWTRWGQTVGPS---QPSDPGVLELPPIQMEHEGEFTCHAQHPL 442
+ L C P + W + GQ + S + G L L ++ G + C A + L
Sbjct: 3043 DVALRCQATGEPTPTIEWLQAGQPLRASRRLRTLPDGSLWLENVETGDAGTYDCVAHNLL 3102
Query: 443 GSQHVSLSLSVHYPPQ 458
GS L V PQ
Sbjct: 3103 GSATARAFLVVRGEPQ 3118
Score = 51.6 bits (122), Expect = 2e-06
Identities = 79/357 (22%), Positives = 124/357 (34%), Gaps = 58/357 (16%)
Query: 153 TALTKKPDVYIPETLEPGQPVTVICVFNWAFKKC-----PAPSFSWTG--AALSPRRTRP 205
T++ + +++ T+ G P + V A C PAP SW L PR R
Sbjct: 2379 TSVAFRVEIHTVPTIRSGPPAVNVSVNQTALLPCQADGVPAPLVSWRKDRVPLDPRSPRF 2438
Query: 206 STSHFSVLSFTPSPQDHDTDLTCHVDFSRKGVSAQRTVRL----RVAYAPKDLIISISHD 261
L P C S R +R+ +A +P +L ++
Sbjct: 2439 EILPEGSLRIQPVLAQDAGHYLCLASNSAGSDRQGRDLRVLEPPAIAPSPSNLTLTA--- 2495
Query: 262 NTSALELQGNVIYLEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTL---- 317
+T AL L C A P + W + L G L
Sbjct: 2496 HTPAL------------------LPCEASGSPKPLVVWWKDGQKLDFRLQQGAYRLLPSN 2537
Query: 318 GLELRGVRAGDSGRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGT 377
L L DS ++ C N +G + ++V PP + Q + TV
Sbjct: 2538 ALLLTAPGPQDSAQFECVVSNEVGEAHRLYQVTVHVPPT---IADDQTDFTVT------M 2588
Query: 378 SLPVLEGQSLRLVCVTHSSPPARLSWTRWGQTVGPS----QPSDPGVLELPPIQMEHEGE 433
PV+ L C + P +SW++ G +G + S G LE+ H G
Sbjct: 2589 MAPVV------LTCHSTGIPAPTVSWSKAGAQLGARGSGYRVSPSGALEIGQALPIHAGR 2642
Query: 434 FTCHAQHPLGSQHVSLSLSVHYPPQLLG-PSC--SWEAEGLHCSCSSQASPAPSLRW 487
+TC A++ G H + L+V P + PS + E + C + P P++ W
Sbjct: 2643 YTCSARNSAGVAHKHVFLTVQASPVVKPLPSVVRAVAEEEVLLPCEASGIPRPTITW 2699
Score = 48.1 bits (113), Expect = 3e-05
Identities = 34/138 (24%), Positives = 50/138 (36%), Gaps = 24/138 (17%)
Query: 374 GNGTSLPVLEGQSLRLVCVTHSSPPARLSWTR-------------------WGQTVGPSQ 414
G ++ + GQSL L C + P + W + WGQ G
Sbjct: 23 GRKANVSGMAGQSLTLECDANGFPVPEIVWLKDAQLVGVPLGWAGYGWDLGWGQVGGHRL 82
Query: 415 PSDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSVHYPPQLLGPSCSWEAEGL--- 471
+ L P IQ G ++C A++ G+ L V PP +LG + E GL
Sbjct: 83 LDEGQSLHFPRIQEGDSGLYSCRAENQAGTAQRDFHLLVLTPPSVLGAGAAQEVLGLAGA 142
Query: 472 --HCSCSSQASPAPSLRW 487
C + P P + W
Sbjct: 143 DVELQCWTSGVPTPQVEW 160
>gi|118572606 hemicentin 1 [Homo sapiens]
Length = 5635
Score = 87.0 bits (214), Expect = 5e-17
Identities = 68/238 (28%), Positives = 107/238 (44%), Gaps = 23/238 (9%)
Query: 275 LEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLG--LELRGVRAGDSGRY 332
++++ L L C A + P A+LSW + L S G L+++ + D+GRY
Sbjct: 2684 VKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGHTLQIKEAQISDTGRY 2743
Query: 333 TCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCV 392
TC A N G + D+++Q PP ++ +L+ NG + V+ + L C
Sbjct: 2744 TCVASNIAGEDELDFDVNIQVPPSFQKLW---EIGNMLDTGRNGEAKDVIINNPISLYCE 2800
Query: 393 THSSPPARLSWTRWGQTVGPSQPSD-----PG--VLELPPIQMEHEGEFTCHAQHPLGSQ 445
T+++PP L+W + G P SD PG VL++P ++E G +TC A + G
Sbjct: 2801 TNAAPPPTLTWYKDGH---PLTSSDKVLILPGGRVLQIPRAKVEDAGRYTCVAVNEAGED 2857
Query: 446 HVSLSLSVHYPPQLLGPSCSWEAE-------GLHCSCSSQASPAPSLRWWL-GEELLE 495
+ + V PP + G + E C S SPAP W G+ LLE
Sbjct: 2858 SLQYDVRVLVPPIIKGANSDLPEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLE 2915
Score = 82.8 bits (203), Expect = 1e-15
Identities = 63/231 (27%), Positives = 103/231 (44%), Gaps = 29/231 (12%)
Query: 283 LRLLCAADSQPPATLSWVLQDRVLSSSHPWG--PRTLGLELRGVRAGDSGRYTCRAENRL 340
+ L C ++ PP TL+W L+SS P L++ + D+GRYTC A N
Sbjct: 2795 ISLYCETNAAPPPTLTWYKDGHPLTSSDKVLILPGGRVLQIPRAKVEDAGRYTCVAVNEA 2854
Query: 341 GSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPPAR 400
G D+ V PP ++ AN + E + VL +S + C++ SP R
Sbjct: 2855 GEDSLQYDVRVLVPP-----IIKGANSDLPEEV------TVLVNKSALIECLSSGSPAPR 2903
Query: 401 LSWTRWGQTVGPSQP----SDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSVHYP 456
SW + GQ + S+ +L++ Q+ G + C A++ GS +L+VH P
Sbjct: 2904 NSWQKDGQPLLEDDHHKFLSNGRILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHVP 2963
Query: 457 PQLLGPSCSWEAEGL--------HCSCSSQASPAPSLRWWLGEELLEGNSS 499
P ++GP ++E L +C P P L W E+ ++ N++
Sbjct: 2964 PSVIGP----KSENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTN 3010
Score = 81.6 bits (200), Expect = 2e-15
Identities = 61/218 (27%), Positives = 97/218 (44%), Gaps = 29/218 (13%)
Query: 283 LRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLG----LELRGVRAGDSGRYTCRAEN 338
+RL C A P +L+W L+D SS G + L L L + D+GRYTC A N
Sbjct: 2029 VRLECEARGIPAPSLTW-LKDGSPVSSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVN 2087
Query: 339 RLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPP 398
G +Q+ +DL V PP +G ++ VL Q++ L+C + + PP
Sbjct: 2088 AAGEKQRDIDLRVYVPP---------------NIMGEEQNVSVLISQAVELLCQSDAIPP 2132
Query: 399 ARLSWTRWGQTV----GPSQPSDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSVH 454
L+W + G + G S + VL++ Q++ G +TC A + G + ++++
Sbjct: 2133 PTLTWLKDGHPLLKKPGLSISENRSVLKIEDAQVQDTGRYTCEATNVAGKTEKNYNVNIW 2192
Query: 455 YPPQLLGPS-----CSWEAEGLHCSCSSQASPAPSLRW 487
PP + G E + C S P P+L W
Sbjct: 2193 VPPNIGGSDELTQLTVIEGNLISLLCESSGIPPPNLIW 2230
Score = 80.9 bits (198), Expect = 4e-15
Identities = 68/275 (24%), Positives = 118/275 (42%), Gaps = 27/275 (9%)
Query: 275 LEVQKGQFLRLLCAADSQPPATLSWVLQDRV--LSSSHPWGPRTLGLELRGVRAGDSGRY 332
L V F+ L C PP LSW+ ++ L+++ P L++ + D G Y
Sbjct: 2974 LTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPGGRTLQIIRAKVSDGGEY 3033
Query: 333 TCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCV 392
TC A N+ G ++ L+V PP +++ S++ V V EG S+ L C
Sbjct: 3034 TCIAINQAGESKKKFSLTVYVPP-SIKDHDSESLSVV----------NVREGTSVSLECE 3082
Query: 393 THSSPPARLSWTRWGQTVGPSQP----SDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVS 448
+++ PP ++W + G+ + S +D +L + ++ G++ C A + G +
Sbjct: 3083 SNAVPPPVITWYKNGRMITESTHVEILADGQMLHIKKAEVSDTGQYVCRAINVAGRDDKN 3142
Query: 449 LSLSVHYPPQLLGPSCSWEAEGLH----CSCSSQASPAPSLRWWLGEELLEGNSSQGSFE 504
L+V+ PP + GP E + +C + P P++ W + +E + S E
Sbjct: 3143 FHLNVYVPPSIEGPEREVIVETISNPVTLTCDATGIPPPTIAWLKNHKRIENSD---SLE 3199
Query: 505 VTPSSAGPWANSSLSLHGGLSSGLRLRCKAWNVHG 539
V S G + S H S C A N+ G
Sbjct: 3200 VRILSGGSKLQIARSQH---SDSGNYTCIASNMEG 3231
Score = 80.5 bits (197), Expect = 5e-15
Identities = 58/224 (25%), Positives = 95/224 (42%), Gaps = 27/224 (12%)
Query: 277 VQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLG----LELRGVRAGDSGRY 332
V +G+ + L C PP T++W+ L + G L L+L+ + D+GRY
Sbjct: 2304 VTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAK--GVEILDEGHILQLKNIHVSDTGRY 2361
Query: 333 TCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCV 392
C A N G + DLSV PP +++ N + ++ V+E S+ L C
Sbjct: 2362 VCVAVNVAGMTDKKYDLSVHAPP------------SIIGNHRSPENISVVEKNSVSLTCE 2409
Query: 393 THSSPPARLSWTRWGQTVGPSQP----SDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVS 448
P ++W + G V S S +L L ME G++TC ++ G +
Sbjct: 2410 ASGIPLPSITWFKDGWPVSLSNSVRILSGGRMLRLMQTTMEDAGQYTCVVRNAAGEERKI 2469
Query: 449 LSLSVHYPPQLLGPSC-----SWEAEGLHCSCSSQASPAPSLRW 487
LSV PP ++G + E + + +C +P P + W
Sbjct: 2470 FGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEITW 2513
Score = 80.5 bits (197), Expect = 5e-15
Identities = 62/220 (28%), Positives = 95/220 (43%), Gaps = 23/220 (10%)
Query: 283 LRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLG-LELRGVRAGDSGRYTCRAENRLG 341
+ L C AD PP ++W R + S + G L++ V+ GD+G YTC A N G
Sbjct: 4096 ITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSGSLQIAFVQPGDAGHYTCMAANVAG 4155
Query: 342 SQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPPARL 401
S + L+V PP R+ ++ + TV EN Q++ L CV P +
Sbjct: 4156 SSSTSTKLTVHVPP---RIRSTEGHYTVNEN-----------SQAI-LPCVADGIPTPAI 4200
Query: 402 SWTR----WGQTVGPSQPSDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSVHYPP 457
+W + +G G L L + +E G +TC A + G ++SL+VH P
Sbjct: 4201 NWKKDNVLLANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAGEDTHTVSLTVHVLP 4260
Query: 458 ---QLLGPSCSWEAEGLHCSCSSQASPAPSLRWWLGEELL 494
+L G + E L SC + P P L W ++
Sbjct: 4261 TFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNII 4300
Score = 76.6 bits (187), Expect = 7e-14
Identities = 80/330 (24%), Positives = 123/330 (37%), Gaps = 57/330 (17%)
Query: 187 PAPSFSWTGAALSPRRTRPSTSHFSVLSFTP-----SPQDHDTDLTCHVDFSRKGVSAQR 241
P P +W L P +SH +L+ Q D + V +R GV +
Sbjct: 3370 PPPQINWLKNGLP----LPLSSHIRLLAAGQVIRIVRAQVSDVAVYTCVASNRAGVD-NK 3424
Query: 242 TVRLRVAYAPKDLIISISHDNTSALELQGNVIYLEVQKGQFLRLLCAADSQPPATLSWVL 301
L+V +AP ++ DN+ E + V KG + C D P +++W+
Sbjct: 3425 HYNLQV-FAPPNM------DNSMGTE------EITVLKGSSTSMACITDGTPAPSMAWLR 3471
Query: 302 QDRVLSSSHPWGPRTLGLELRGVRAG--DSGRYTCRAENRLGSQQQALDLSVQYPPENLR 359
+ L T G+ L+ ++A DSG+YTC A N G + L V PP
Sbjct: 3472 DGQPLGLDAHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEPPH--- 3528
Query: 360 VMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPPARLSWTRWG---------QTV 410
+ + V+ L L C+ P +++W + G QT+
Sbjct: 3529 ----------INGSEEHEEISVIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTDQVQTL 3578
Query: 411 GPSQPSDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSVHYPPQLLGPSCSWEAEG 470
G + VL + Q+E G +TC A P G + VH PP + G +
Sbjct: 3579 GGGE-----VLRISTAQVEDTGRYTCLASSPAGDDDKEYLVRVHVPPNIAGTDEPRDITV 3633
Query: 471 LH-----CSCSSQASPAPSLRWWLGEELLE 495
L C S A P P + W E L+
Sbjct: 3634 LRNRQVTLECKSDAVPPPVITWLRNGERLQ 3663
Score = 75.9 bits (185), Expect = 1e-13
Identities = 57/245 (23%), Positives = 102/245 (41%), Gaps = 24/245 (9%)
Query: 275 LEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLG--LELRGVRAGDSGRY 332
+ V + + + L C +D+ PP ++W+ L ++ + G L++ GD+ Y
Sbjct: 3631 ITVLRNRQVTLECKSDAVPPPVITWLRNGERLQATPRVRILSGGRYLQINNADLGDTANY 3690
Query: 333 TCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCV 392
TC A N G + L+V PP N++ G SL +L +S L C+
Sbjct: 3691 TCVASNIAGKTTREFILTVNVPP-NIK--------------GGPQSLVILLNKSTVLECI 3735
Query: 393 THSSPPARLSWTRWGQTVGPSQPS----DPGVLELPPIQMEHEGEFTCHAQHPLGSQHVS 448
P R++W + G + + + G L + + G + C A + G+
Sbjct: 3736 AEGVPTPRITWRKDGAVLAGNHARYSILENGFLHIQSAHVTDTGRYLCMATNAAGTDRRR 3795
Query: 449 LSLSVHYPPQLL-GPSCSWEAEGLH--CSCSSQASPAPSLRWWLGEELLEGNSSQGSFEV 505
+ L VH PP + GP+ + +C + P PS+ W LL + +Q S+ +
Sbjct: 3796 IDLQVHVPPSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRL 3855
Query: 506 TPSSA 510
S +
Sbjct: 3856 LSSGS 3860
Score = 75.5 bits (184), Expect = 2e-13
Identities = 82/344 (23%), Positives = 138/344 (40%), Gaps = 51/344 (14%)
Query: 163 IPETLEPGQPVTVICVFNWAFKKCPAPSFSWT--GAALSPRRTRPSTSHFSVLSFTPSPQ 220
I T+E G PVT+ C + P PS W+ G +S + S L
Sbjct: 989 ILSTIE-GIPVTLPCKASGN----PKPSVIWSKKGELISTSSAKFSAGADGSLYVVSPGG 1043
Query: 221 DHDTDLTCHVDFSRKGVSAQRTVRLRVAYAPKDLIISISHDNTSALELQGNVIYLEVQKG 280
+ + C + A+R V+L V P+ + D Q + + V G
Sbjct: 1044 EESGEYVCTA--TNTAGYAKRKVQLTVYVRPR-----VFGDQRGLS--QDKPVEISVLAG 1094
Query: 281 QFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTL-----GLELRGVRAGDSGRYTCR 335
+ + L C S PP ++W + +++S P+ PR +++ R DSG Y C
Sbjct: 1095 EEVTLPCEVKSLPPPIITWAKETQLIS---PFSPRHTFLPSGSMKITETRTSDSGMYLCV 1151
Query: 336 AENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHS 395
A N G+ QA+ L+V PP+ R L V GQ + + C
Sbjct: 1152 ATNIAGNVTQAVKLNVHVPPKIQR---------------GPKHLKVQVGQRVDIPCNAQG 1196
Query: 396 SPPARLSWTRWGQTV---GPSQPSDP-GVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSL 451
+P ++W++ G T+ G S+P G L + G +TC A + G+ ++L
Sbjct: 1197 TPLPVITWSKGGSTMLVDGEHHVSNPDGTLSIDQATPSDAGIYTCVATNIAGTDETEITL 1256
Query: 452 SVHYPPQL--LGPSCSW------EAEGLHCSCSSQASPAPSLRW 487
V PP + L P + + + C ++ +P P+++W
Sbjct: 1257 HVQEPPTVEDLEPPYNTTFQERVANQRIEFPCPAKGTPKPTIKW 1300
Score = 73.9 bits (180), Expect = 5e-13
Identities = 61/235 (25%), Positives = 96/235 (40%), Gaps = 40/235 (17%)
Query: 275 LEVQKGQFLRLLCAADSQPPATLSW------VLQD-----RVLSSSHPWGPRTLGLELRG 323
L V +G + LLC + PP L W VL D R+LS G R L + +
Sbjct: 2206 LTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILS-----GGRQLQISI-- 2258
Query: 324 VRAGDSGRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLE 383
D+ Y+C A N G+ ++ +L V P T+ + + T + V
Sbjct: 2259 AEKSDAALYSCVASNVAGTAKKEYNLQVYIRP------------TITNSGSHPTEIIVTR 2306
Query: 384 GQSLRLVCVTHSSPPARLSWTRWGQTV----GPSQPSDPGVLELPPIQMEHEGEFTCHAQ 439
G+S+ L C PP ++W + G + G + +L+L I + G + C A
Sbjct: 2307 GKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEGHILQLKNIHVSDTGRYVCVAV 2366
Query: 440 HPLGSQHVSLSLSVHYPPQLLGPSCS------WEAEGLHCSCSSQASPAPSLRWW 488
+ G LSVH PP ++G S E + +C + P PS+ W+
Sbjct: 2367 NVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEKNSVSLTCEASGIPLPSITWF 2421
Score = 72.4 bits (176), Expect = 1e-12
Identities = 53/219 (24%), Positives = 92/219 (42%), Gaps = 29/219 (13%)
Query: 285 LLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLG----LELRGVRAGDSGRYTCRAENRL 340
L C A PP T++W+ + + +S R L L++ + DSG YTC A N
Sbjct: 3171 LTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNME 3230
Query: 341 GSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPPAR 400
G Q+ LS+Q PP S A + + + VL G+++ LVC + P
Sbjct: 3231 GKAQKYYFLSIQVPP-------SVAGAEI------PSDVSVLLGENVELVCNANGIPTPL 3277
Query: 401 LSWTRWGQTVGPSQ------PSDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSVH 454
+ W + G+ + + ++ L + G++TC A +P G + +L+V+
Sbjct: 3278 IQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVY 3337
Query: 455 YPPQLLGPSCSWEA------EGLHCSCSSQASPAPSLRW 487
P + G E ++ C + +P P + W
Sbjct: 3338 VTPTIRGNKDEAEKLMTLVDTSINIECRATGTPPPQINW 3376
Score = 71.2 bits (173), Expect = 3e-12
Identities = 55/247 (22%), Positives = 98/247 (39%), Gaps = 26/247 (10%)
Query: 265 ALELQGNVIYLEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLG--LELR 322
A+E Y V L L C PP T+ W+ +++ + G L +
Sbjct: 1734 AIEGGDETSYFIVMVNNLLELDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNGRKLVIA 1793
Query: 323 GVRAGDSGRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVL 382
+ ++G Y C A N G ++ +++V PP + S + V V+
Sbjct: 1794 QAQVSNTGLYRCMAANTAGDHKKEFEVTVHVPP---TIKSSGLSERV-----------VV 1839
Query: 383 EGQSLRLVCVTHSSPPARLSWTRWGQTVGPSQ-----PSDPGVLELPPIQMEHEGEFTCH 437
+ + + L C+ + P ++W + Q V +Q S VL++ +E G +TC
Sbjct: 1840 KYKPVALQCIANGIPNPSITWLKDDQPVNTAQGNLKIQSSGRVLQIAKTLLEDAGRYTCV 1899
Query: 438 AQHPLGSQHVSLSLSVHYPPQL-----LGPSCSWEAEGLHCSCSSQASPAPSLRWWLGEE 492
A + G + L VH PP L + + + C + +P P + W+
Sbjct: 1900 ATNAAGETQQHIQLHVHEPPSLEDAGKMLNETVLVSNPVQLECKAAGNPVPVITWYKDNR 1959
Query: 493 LLEGNSS 499
LL G++S
Sbjct: 1960 LLSGSTS 1966
Score = 70.9 bits (172), Expect = 4e-12
Identities = 48/179 (26%), Positives = 74/179 (41%), Gaps = 23/179 (12%)
Query: 319 LELRGVRAGDSGRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTS 378
L L+ R D GRY C N G Q + + L++ PP + N T T
Sbjct: 1510 LHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIYIPPS-----IKGGNVT--------TD 1556
Query: 379 LPVLEGQSLRLVCVTHSSPPARLSWTRWGQTVGPSQPS---DPG-VLELPPIQMEHEGEF 434
+ VL ++L C T P ++W + GQ + S + D G L +P Q+ +
Sbjct: 1557 ISVLINSLIKLECETRGLPMPAITWYKDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATY 1616
Query: 435 TCHAQHPLGSQHVSLSLSVHYPPQLLGPSCS------WEAEGLHCSCSSQASPAPSLRW 487
TCH + G+ S + V+ PP + G + A L C + +P+P L W
Sbjct: 1617 TCHVANVAGTAEKSFHVDVYVPPMIEGNLATPLNKQVVIAHSLTLECKAAGNPSPILTW 1675
Score = 70.1 bits (170), Expect = 7e-12
Identities = 81/365 (22%), Positives = 132/365 (36%), Gaps = 68/365 (18%)
Query: 153 TALTKKPDVYIPETLEPGQPVTVICVFNWAFKKC-----PAPSFSWT--GAALSPRRTRP 205
T L V++ ++ + + V N +C PAPS +W G+ +S
Sbjct: 2000 TELFYSLQVHVAPSISGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGSPVSSFSNGL 2059
Query: 206 STSHFSVLSFTPSPQDHDTDLTCHVDFSRKGVSAQRTVRLRVAYAPKDLIISISHDNTSA 265
+ S Q DT V + G QR + LRV Y P +++
Sbjct: 2060 QVLSGGRILALTSAQISDTGRYTCVAVNAAG-EKQRDIDLRV-YVPPNIM---------- 2107
Query: 266 LELQGNVIYLEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPW--------GPRTL 317
G + V Q + LLC +D+ PP TL+W L HP
Sbjct: 2108 ----GEEQNVSVLISQAVELLCQSDAIPPPTLTW------LKDGHPLLKKPGLSISENRS 2157
Query: 318 GLELRGVRAGDSGRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNG- 376
L++ + D+GRYTC A N G ++ ++++ PP N+G
Sbjct: 2158 VLKIEDAQVQDTGRYTCEATNVAGKTEKNYNVNIWVPP----------------NIGGSD 2201
Query: 377 --TSLPVLEGQSLRLVCVTHSSPPARLSWTRWGQTVGPSQP------SDPGVLELPPIQM 428
T L V+EG + L+C + PP L W + G V S L++ +
Sbjct: 2202 ELTQLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEK 2261
Query: 429 EHEGEFTCHAQHPLGSQHVSLSLSVHYPPQLLGPSCS------WEAEGLHCSCSSQASPA 482
++C A + G+ +L V+ P + + + C Q P
Sbjct: 2262 SDAALYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHPTEIIVTRGKSISLECEVQGIPP 2321
Query: 483 PSLRW 487
P++ W
Sbjct: 2322 PTVTW 2326
Score = 68.9 bits (167), Expect = 1e-11
Identities = 58/237 (24%), Positives = 98/237 (41%), Gaps = 27/237 (11%)
Query: 275 LEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLGLELRGVRAG--DSGRY 332
+ V + + L C A P +++W +S S+ + G LR ++ D+G+Y
Sbjct: 2396 ISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRILSGGRMLRLMQTTMEDAGQY 2455
Query: 333 TCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCV 392
TC N G +++ LSV PP + LE++ V E QS+ L C
Sbjct: 2456 TCVVRNAAGEERKIFGLSVLVPPHIV-------GENTLEDV------KVKEKQSVTLTCE 2502
Query: 393 THSSPPARLSWTRWGQTVGPSQP----SDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVS 448
+P ++W + GQ + + S L++ +Q+ H G +TC A P G + S
Sbjct: 2503 VTGNPVPEITWHKDGQPLQEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRS 2562
Query: 449 LSLSVHYPPQLLGPSCSWEAEGL--------HCSCSSQASPAPSLRWWLGEELLEGN 497
SL+V P + G E + C + + P ++ W+ LE N
Sbjct: 2563 FSLNVFVSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESN 2619
Score = 68.9 bits (167), Expect = 1e-11
Identities = 99/434 (22%), Positives = 156/434 (35%), Gaps = 69/434 (15%)
Query: 81 KTGAPVATNNQSREVEMSTRDRFQLTGDPGKGSCSLVIRDAQREDEAWYFFRVERGSRVR 140
K G PV+ +N R + R T G + V+R+A E+ +
Sbjct: 2422 KDGWPVSLSNSVRILSGGRMLRLMQTTMEDAGQYTCVVRNAAGEERKIFG---------- 2471
Query: 141 HSFLSNAFFLKVTALTKKPDVYIPETLEPGQPVTVICVFNWAFKKCPAPSFSW--TGAAL 198
LS + DV + E Q VT+ C P P +W G L
Sbjct: 2472 ---LSVLVPPHIVGENTLEDVKVKEK----QSVTLTCEVTGN----PVPEITWHKDGQPL 2520
Query: 199 SPRRTRPSTSHFSVLSFTPSPQDHDTDLTCHVDFSRKGVSAQRTVRLRVAYAPKDLIISI 258
S L T H TC S R+ L V +P I +
Sbjct: 2521 QEDEAHHIISGGRFLQITNVQVPHTGRYTCLA--SSPAGHKSRSFSLNVFVSPT--IAGV 2576
Query: 259 SHDNTSALELQGNVIYLEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPW----GP 314
D GN + V L+C A S PPAT++W L S+ G
Sbjct: 2577 GSD--------GNPEDVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRILPGG 2628
Query: 315 RTLGLELRGVRAGDSGRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLG 374
RTL ++ + ++GRY+C A N G + ++ V PP N+ L G
Sbjct: 2629 RTL--QILNAQEDNAGRYSCVATNEAGEMIKHYEVKVYIPP--------IINKGDLWGPG 2678
Query: 375 -NGTSLPVLEGQSLRLVCVTHSSPPARLSWTRWGQTVGPSQ----PSDPGVLELPPIQME 429
+ + + +L L C ++ P A LSW + GQ + ++ L++ Q+
Sbjct: 2679 LSPKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGHTLQIKEAQIS 2738
Query: 430 HEGEFTCHAQHPLGSQHVSLSLSVHYPP---------QLLGPSCSWEAEG------LHCS 474
G +TC A + G + +++ PP +L + EA+ +
Sbjct: 2739 DTGRYTCVASNIAGEDELDFDVNIQVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLY 2798
Query: 475 CSSQASPAPSLRWW 488
C + A+P P+L W+
Sbjct: 2799 CETNAAPPPTLTWY 2812
Score = 68.6 bits (166), Expect = 2e-11
Identities = 65/266 (24%), Positives = 113/266 (42%), Gaps = 25/266 (9%)
Query: 275 LEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLGLELRGVRAG--DSGRY 332
L +G + L C A P ++ W + ++S+S L V G +SG Y
Sbjct: 990 LSTIEGIPVTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGADGSLYVVSPGGEESGEY 1049
Query: 333 TCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCV 392
C A N G ++ + L+V P RV Q + + VL G+ + L C
Sbjct: 1050 VCTATNTAGYAKRKVQLTVYVRP---RVFGDQRGLSQ----DKPVEISVLAGEEVTLPCE 1102
Query: 393 THSSPPARLSWTRWGQTVGPSQPSDP----GVLELPPIQMEHEGEFTCHAQHPLGSQHVS 448
S PP ++W + Q + P P G +++ + G + C A + G+ +
Sbjct: 1103 VKSLPPPIITWAKETQLISPFSPRHTFLPSGSMKITETRTSDSGMYLCVATNIAGNVTQA 1162
Query: 449 LSLSVHYPPQLL-GPSCSWEAEG--LHCSCSSQASPAPSLRWWLGEE--LLEG----NSS 499
+ L+VH PP++ GP G + C++Q +P P + W G L++G ++
Sbjct: 1163 VKLNVHVPPKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNP 1222
Query: 500 QGSFEV---TPSSAGPWANSSLSLHG 522
G+ + TPS AG + + ++ G
Sbjct: 1223 DGTLSIDQATPSDAGIYTCVATNIAG 1248
Score = 65.9 bits (159), Expect = 1e-10
Identities = 79/354 (22%), Positives = 134/354 (37%), Gaps = 56/354 (15%)
Query: 160 DVYIPETLE-PGQPVTVICVFNWAFKKC-----PAPSFSWTGAALSPRRTRPSTS----- 208
+VY+P ++E P + V V + N C P P+ +W + +R S S
Sbjct: 3146 NVYVPPSIEGPEREVIVETISNPVTLTCDATGIPPPTIAWLK---NHKRIENSDSLEVRI 3202
Query: 209 --HFSVLSFTPSPQDHDTDLTCHVDFSRKGVSAQRTVRLRVAYAPKDLIISISHDNTSAL 266
S L S + TC S AQ+ L + P + +
Sbjct: 3203 LSGGSKLQIARSQHSDSGNYTCIA--SNMEGKAQKYYFLSIQVPP----------SVAGA 3250
Query: 267 ELQGNVIYLEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLG----LELR 322
E+ +V V G+ + L+C A+ P + W+ + ++S R L +
Sbjct: 3251 EIPSDV---SVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIY 3307
Query: 323 GVRAGDSGRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVL 382
G D+G+YTC A N G + + +L+V P T+ N L L
Sbjct: 3308 GALTSDTGKYTCVATNPAGEEDRIFNLNVYVTP------------TIRGNKDEAEKLMTL 3355
Query: 383 EGQSLRLVCVTHSSPPARLSWTRWGQTVGPSQP----SDPGVLELPPIQMEHEGEFTCHA 438
S+ + C +PP +++W + G + S + V+ + Q+ +TC A
Sbjct: 3356 VDTSINIECRATGTPPPQINWLKNGLPLPLSSHIRLLAAGQVIRIVRAQVSDVAVYTCVA 3415
Query: 439 QHPLGSQHVSLSLSVHYPPQLLGPSCSWEAEGLHCS-----CSSQASPAPSLRW 487
+ G + +L V PP + + E L S C + +PAPS+ W
Sbjct: 3416 SNRAGVDNKHYNLQVFAPPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMAW 3469
Score = 65.1 bits (157), Expect = 2e-10
Identities = 53/221 (23%), Positives = 96/221 (43%), Gaps = 23/221 (10%)
Query: 277 VQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHP-WGPRTLG--LELRGVRAGDSGRYT 333
V K + + L C A+ P +++W+ D+ ++++ ++ G L++ D+GRYT
Sbjct: 1838 VVKYKPVALQCIANGIPNPSITWLKDDQPVNTAQGNLKIQSSGRVLQIAKTLLEDAGRYT 1897
Query: 334 CRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVT 393
C A N G QQ + L V PP LE+ G + VL ++L C
Sbjct: 1898 CVATNAAGETQQHIQLHVHEPPS-------------LEDAGKMLNETVLVSNPVQLECKA 1944
Query: 394 HSSPPARLSWTRWGQTVGPSQP----SDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSL 449
+P ++W + + + S + ++++ Q+ G + C A + G+ +
Sbjct: 1945 AGNPVPVITWYKDNRLLSGSTSMTFLNRGQIIDIESAQISDAGIYKCVAINSAGATELFY 2004
Query: 450 SLSVHYPPQLLGPSCSWEA---EGLHCSCSSQASPAPSLRW 487
SL VH P + G + + C ++ PAPSL W
Sbjct: 2005 SLQVHVAPSISGSNNMVAVVVNNPVRLECEARGIPAPSLTW 2045
Score = 64.3 bits (155), Expect = 4e-10
Identities = 71/281 (25%), Positives = 112/281 (39%), Gaps = 40/281 (14%)
Query: 275 LEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGP------RTLGLELRGVRAGD 328
+ ++ G + L C P T+ W D + S P+ RT L + + A D
Sbjct: 802 VSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASD 861
Query: 329 SGRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLP-VLEGQSL 387
G Y C AEN+ G Q ++V V +G S+ V+EGQ L
Sbjct: 862 KGTYICEAENQFGKIQSETTVTV--------------TGLVAPLIGISPSVANVIEGQQL 907
Query: 388 RLVCVTHSSPPARLSWTRWGQTVGPSQPS------DPGVLELPPIQMEHEGEFTCHAQHP 441
L C + P + RW + + G L + +Q++ GE+TC A +
Sbjct: 908 TLPCTLLAGNP--IPERRWIKNSAMLLQNPYITVRSDGSLHIERVQLQDGGEYTCVASNV 965
Query: 442 LGSQHVSLSLSVHYPPQLL-GPSCSWEAEGLHCS--CSSQASPAPSLRWWLGEELLEGNS 498
G+ + + S+ VH P + G EG+ + C + +P PS+ W EL+ +S
Sbjct: 966 AGTNNKTTSVVVHVLPTIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELISTSS 1025
Query: 499 SQGSFEVTPSSAGPWANSSLSLHGGLSSGLRLRCKAWNVHG 539
++ SAG + + GG SG C A N G
Sbjct: 1026 AK-------FSAGADGSLYVVSPGGEESG-EYVCTATNTAG 1058
Score = 64.3 bits (155), Expect = 4e-10
Identities = 83/369 (22%), Positives = 137/369 (37%), Gaps = 58/369 (15%)
Query: 161 VYIPETLEPGQPVTVICVFNWAFKKC-----PAPSFSWT--GAALSPRRTRPSTSHFSVL 213
V +P ++ G VI + +C P P +W GA L+ R +S+L
Sbjct: 3709 VNVPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVLAGNHAR-----YSIL 3763
Query: 214 S--FTPSPQDHDTDLTCHVDFSRKGVSA-QRTVRLRVAYAPKDLIISISHDNTSALELQG 270
F H TD ++ + +R + L+V P SI+ T+
Sbjct: 3764 ENGFLHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHVPP-----SIAPGPTNM----- 3813
Query: 271 NVIYLEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTL----GLELRGVRA 326
+ + VQ L C A P +++W +L+ L L +
Sbjct: 3814 -TVIVNVQT----TLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSV 3868
Query: 327 GDSGRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQS 386
D+ Y C N G ++ +DL+VQ PP S A+ T V +
Sbjct: 3869 DDTATYECTVTNGAGDDKRTVDLTVQVPP-------SIADEP--------TDFLVTKHAP 3913
Query: 387 LRLVCVTHSSPPARLSWTRWGQTVGPSQPS----DPGVLELPPIQMEHEGEFTCHAQHPL 442
+ C P + WT+ G + P G +E+ Q+ H G +TC A++
Sbjct: 3914 AVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSSGAIEILATQLNHAGRYTCVARNAA 3973
Query: 443 GSQHVSLSLSVHYPPQLLGPSCSWEA---EGLHCSCSSQASPAPSLRWWLGEELLEGNSS 499
GS H ++L VH PP + + C + +P+P + W +E + N+S
Sbjct: 3974 GSAHRHVTLHVHEPPVIQPQPSELHVILNNPILLPCEATGTPSPFITW--QKEGINVNTS 4031
Query: 500 QGSFEVTPS 508
+ V PS
Sbjct: 4032 GRNHAVLPS 4040
Score = 63.5 bits (153), Expect = 6e-10
Identities = 70/323 (21%), Positives = 123/323 (38%), Gaps = 49/323 (15%)
Query: 184 KKCPAPSFSW--TGAALSPRRTRPSTSHFSVLSFTPSPQDHDTDLTCHVDFSRKGVSAQR 241
K P P+ W G L+ R S L S +D V + G + +R
Sbjct: 1291 KGTPKPTIKWLHNGRELTGREPGISILEDGTLLVIASVTPYDNGEYICVAVNEAGTT-ER 1349
Query: 242 TVRLRVAYAPKDLIISISHDNTSALELQGNVIYLEVQKGQFLRLLCAADSQPPATLSWVL 301
L+V P ++ + V + V Q L C + P + W
Sbjct: 1350 KYNLKVHVPP-------------VIKDKEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYK 1396
Query: 302 QDRVLSSSHPWGPRTLGLELRGVRAG--DSGRYTCRAENRLGSQQQALDLSVQYPPENLR 359
+ ++ S G L+ RA D+GRY+C+A N G+ Q+ ++ V PP
Sbjct: 1397 DNVQVTESSTIQTVNNGKILKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVLVPP---- 1452
Query: 360 VMVSQANRTVLENLGNGTSLP----VLEGQSLRLVCVTHSSPPARLSWTRWGQTVGPSQP 415
T++ GT+ P V+ + + L C +P + W + G+ + P
Sbjct: 1453 --------TII-----GTNFPNEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDP 1499
Query: 416 S----DPG-VLELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSVHYPPQLLGPSCSWEAEG 470
+ D G VL L + +G + C + G Q + L+++ PP + G + + +
Sbjct: 1500 NVELLDRGQVLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIYIPPSIKGGNVTTDISV 1559
Query: 471 L-----HCSCSSQASPAPSLRWW 488
L C ++ P P++ W+
Sbjct: 1560 LINSLIKLECETRGLPMPAITWY 1582
Score = 62.8 bits (151), Expect = 1e-09
Identities = 75/312 (24%), Positives = 116/312 (37%), Gaps = 44/312 (14%)
Query: 187 PAPSFSWT--GAALSPRRTRPSTSHFSVLSFTPSPQDHDTDLTCHVDFSRKGVSAQRTVR 244
P PS WT G L PR + + +H TC V + G SA R V
Sbjct: 3924 PFPSIHWTKNGIRLLPRGDGYRILSSGAIEILATQLNHAGRYTC-VARNAAG-SAHRHVT 3981
Query: 245 LRVAYAPKDLIISISHDNTSALELQGNVIYLEVQKGQFLRLLCAADSQPPATLSWVLQDR 304
L V P +Q L V + L C A P ++W +
Sbjct: 3982 LHVHEPPV---------------IQPQPSELHVILNNPILLPCEATGTPSPFITWQKEGI 4026
Query: 305 VLSSS---HPWGPRTLGLELRGVRAGDSGRYTCRAENRLGSQQQALDLSVQYPPENLRVM 361
+++S H P GL++ D+G Y C A+N G+ + L+VQ PP V+
Sbjct: 4027 NVNTSGRNHAVLPSG-GLQISRAVREDAGTYMCVAQNPAGTALGKIKLNVQVPP----VI 4081
Query: 362 VSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPPARLSWTRWGQTVGPS---QPSDP 418
V + + + L C PP ++W + G+ + S +
Sbjct: 4082 SPHLKEYV-----------IAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSS 4130
Query: 419 GVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSVHYPPQLLGPSCSW---EAEGLHCSC 475
G L++ +Q G +TC A + GS S L+VH PP++ + E C
Sbjct: 4131 GSLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVHVPPRIRSTEGHYTVNENSQAILPC 4190
Query: 476 SSQASPAPSLRW 487
+ P P++ W
Sbjct: 4191 VADGIPTPAINW 4202
Score = 62.4 bits (150), Expect = 1e-09
Identities = 55/236 (23%), Positives = 92/236 (38%), Gaps = 27/236 (11%)
Query: 266 LELQGNVIYLEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLG----LEL 321
LE N + E Q + C A P T+ W+ R L+ P G L L +
Sbjct: 1267 LEPPYNTTFQERVANQRIEFPCPAKGTPKPTIKWLHNGRELTGREP-GISILEDGTLLVI 1325
Query: 322 RGVRAGDSGRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPV 381
V D+G Y C A N G+ ++ +L V PP V+++ T++ V
Sbjct: 1326 ASVTPYDNGEYICVAVNEAGTTERKYNLKVHVPP-------------VIKDKEQVTNVSV 1372
Query: 382 LEGQSLRLVCVTHSSPPARLSWTRWGQTVGPSQP----SDPGVLELPPIQMEHEGEFTCH 437
L Q L C +P + W + V S ++ +L+L E G ++C
Sbjct: 1373 LLNQLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNNGKILKLFRATPEDAGRYSCK 1432
Query: 438 AQHPLGSQHVSLSLSVHYPPQLLGPSCSWEA-----EGLHCSCSSQASPAPSLRWW 488
A + G+ ++ V PP ++G + E + C + +P P + W+
Sbjct: 1433 AINIAGTSQKYFNIDVLVPPTIIGTNFPNEVSVVLNRDVALECQVKGTPFPDIHWF 1488
Score = 60.5 bits (145), Expect = 5e-09
Identities = 90/371 (24%), Positives = 136/371 (36%), Gaps = 54/371 (14%)
Query: 267 ELQGNVIYLEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLGLELRGVRA 326
EL G+V + KG+ LRL C A P L+W + ++ + L + V
Sbjct: 4264 ELPGDV---SLNKGEQLRLSCKATGIPLPKLTWTFNNNIIPAHFDSVNGHSELVIERVSK 4320
Query: 327 GDSGRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQS 386
DSG Y C AEN +G + + V+ PP V +E LG L
Sbjct: 4321 EDSGTYVCTAENSVGFVKAIGFVYVKEPP----VFKGDYPSNWIEPLGGNAILN------ 4370
Query: 387 LRLVCVTHSSPPARLSWTRWGQTVGPS---QPSDPGVLELPPIQMEHEGEFTCHAQHPLG 443
C P + W R G + S + G L + E G++TC A + G
Sbjct: 4371 ----CEVKGDPTPTIQWNRKGVDIEISHRIRQLGNGSLAIYGTVNEDAGDYTCVATNEAG 4426
Query: 444 SQHVSLSLSVHYPPQL-LGPSCSWEAEG--LHCSCSSQASPAPSLRWWLGEELLEGNSSQ 500
S+SL++ PP + L P + G + +C + P P++ W S Q
Sbjct: 4427 VVERSMSLTLQSPPIITLEPVETVINAGGKIILNCQATGEPQPTITW----------SRQ 4476
Query: 501 GSFEVTPSSAGPWANSSLSLHGGLSSGL-RLRCKAWNVHGAQSGSVFQLLPGKLEHGGGL 559
G +N+SL + C A N+ GSV +P ++ GG
Sbjct: 4477 GHSISWDDRVNVLSNNSLYIADAQKEDTSEFECVARNL----MGSVLVRVPVIVQVHGGF 4532
Query: 560 GLGAALGAGVAALLAFCSCLVVFRVKICRKEARKRA-AAEQDVPSTLGPISQGHQHECSA 618
+A A CS C K +KR+ Q +P+ G QG E
Sbjct: 4533 SQWSAWRA--------CSV-------TCGKGIQKRSRLCNQPLPANGGKPCQGSDLEMRN 4577
Query: 619 GSSQDHPPPGA 629
++ P G+
Sbjct: 4578 CQNKPCPVDGS 4588
Score = 57.4 bits (137), Expect = 4e-08
Identities = 76/374 (20%), Positives = 139/374 (37%), Gaps = 56/374 (14%)
Query: 158 KPDVYIPETLEPGQPVTVICVFNWAFKKC-------PAPSFSWTGAALSPRRTRPSTSHF 210
K +YIP +++ G T I V + K P P+ +W P + +
Sbjct: 1539 KLTIYIPPSIKGGNVTTDISVLINSLIKLECETRGLPMPAITWYKDG-QPIMSSSQALYI 1597
Query: 211 SVLSFTPSPQDHDTD---LTCHVDFSRKGVSAQRTVRLRVAYAPKDLIISISHDNTSALE 267
+ P+ +D TCHV + +A+++ + V P
Sbjct: 1598 DKGQYLHIPRAQVSDSATYTCHV--ANVAGTAEKSFHVDVYVPPM--------------- 1640
Query: 268 LQGNV---IYLEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLG--LELR 322
++GN+ + +V L L C A P L+W+ + ++ G LE+
Sbjct: 1641 IEGNLATPLNKQVVIAHSLTLECKAAGNPSPILTWLKDGVPVKANDNIRIEAGGKKLEIM 1700
Query: 323 GVRAGDSGRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVL 382
+ D G+Y C A + G ++ ++ V PP +E + V+
Sbjct: 1701 SAQEIDRGQYICVATSVAGEKEIKYEVDVLVPP-------------AIEGGDETSYFIVM 1747
Query: 383 EGQSLRLVCVTHSSPPARLSWTRWGQTV----GPSQPSDPGVLELPPIQMEHEGEFTCHA 438
L L C SPP + W + GQ + G + L + Q+ + G + C A
Sbjct: 1748 VNNLLELDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNGRKLVIAQAQVSNTGLYRCMA 1807
Query: 439 QHPLGSQHVSLSLSVHYPPQLLGPSCSWEA----EGLHCSCSSQASPAPSLRWWLGEELL 494
+ G ++VH PP + S + + C + P PS+ W ++ +
Sbjct: 1808 ANTAGDHKKEFEVTVHVPPTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQPV 1867
Query: 495 EGNSSQGSFEVTPS 508
N++QG+ ++ S
Sbjct: 1868 --NTAQGNLKIQSS 1879
Score = 56.6 bits (135), Expect = 8e-08
Identities = 54/230 (23%), Positives = 93/230 (40%), Gaps = 27/230 (11%)
Query: 277 VQKGQFLRLLCAADSQPPATLSWVLQDRVLS-SSHPWGPRTLGLELRGVRAGDSGRYTCR 335
+Q GQ + C+ DS P TLS+V L + ++ L++ V D G Y C
Sbjct: 444 LQPGQ---IPCSVDSLLPFTLSFVRNGVTLGVDQYLKESASVNLDIAKVTLSDEGFYECI 500
Query: 336 AENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHS 395
A + G+ + V PP ++V ++ V G+ L C+ S
Sbjct: 501 AVSSAGTGRAQTFFDVSEPPPVIQV---------------PNNVTVTPGERAVLTCLIIS 545
Query: 396 SPPARLSWTRWGQTVGPSQPSDPGV-----LELPPIQMEHEGEFTCHAQHPLGSQHVSLS 450
+ L+W R + V ++P+ LEL ++ GE+ C GS S+
Sbjct: 546 AVDYNLTWQRNDRDVRLAEPARIRTLANLSLELKSVKFNDAGEYHCMVSSEGGSSAASVF 605
Query: 451 LSVHYPPQLLGPSCSWEAEG---LHCSCSSQASPAPSLRWWLGEELLEGN 497
L+V PP++ + G + CS+ P P + W + + + G+
Sbjct: 606 LTVQEPPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGS 655
Score = 53.5 bits (127), Expect = 6e-07
Identities = 51/224 (22%), Positives = 89/224 (39%), Gaps = 24/224 (10%)
Query: 277 VQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLG---LELRGVRAGDSGRYT 333
V G+ L C S L+W DR + + P RTL LEL+ V+ D+G Y
Sbjct: 531 VTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLANLSLELKSVKFNDAGEYH 590
Query: 334 CRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVT 393
C + GS ++ L+VQ PP +V V N++ G + ++C
Sbjct: 591 CMVSSEGGSSAASVFLTVQEPP---KVTVMPKNQS------------FTGGSEVSIMCSA 635
Query: 394 HSSPPARLSWTRWGQTVGPS---QPSDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLS 450
P +++WT + S + + G L + + G + C A + G+ + +
Sbjct: 636 TGYPKPKIAWTVNDMFIVGSHRYRMTSDGTLFIKNAAPKDAGIYGCLASNSAGTDKQNST 695
Query: 451 LSVHYPPQLLGPSCSW---EAEGLHCSCSSQASPAPSLRWWLGE 491
L P+L+ + C + P P ++W+ G+
Sbjct: 696 LRYIEAPKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGD 739
Score = 45.4 bits (106), Expect = 2e-04
Identities = 107/470 (22%), Positives = 166/470 (35%), Gaps = 86/470 (18%)
Query: 115 SLVIRDAQREDEAWYFFRV--ERGSRVRHSFLSNAFFLKVTALTKKPDVYIPETLEPGQP 172
SL ++ + D Y V E GS FL+ KVT + K ++ G
Sbjct: 575 SLELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPPKVTVMPKN------QSFTGGSE 628
Query: 173 VTVICVFNWAFKKCPAPSFSWTGAAL----SPRRTRPSTSHFSVLSFTPSPQDHDTDLTC 228
V+++C + P P +WT + S R S + + P D +
Sbjct: 629 VSIMC----SATGYPKPKIAWTVNDMFIVGSHRYRMTSDGTLFIKNAAPK----DAGIYG 680
Query: 229 HVDFSRKGVSAQRTVRLRVAYAPKDLIISISHDNTSALELQGNVIYLEVQKGQFLRLLCA 288
+ + G Q + LR APK +++ + L G++ +E C
Sbjct: 681 CLASNSAGTDKQNST-LRYIEAPKLMVVQ-----SELLVALGDITVME----------CK 724
Query: 289 ADSQPPATLSWVLQDRVLSSSHPW--GPRTLGLELRGVRAGDSGRYTCRAENRLGSQQQA 346
PP + W D L S P L+++ + D+G YTC A N G
Sbjct: 725 TSGIPPPQVKWFKGDLELRPSTFLIIDPLLGLLKIQETQDLDAGDYTCVAINEAGRATGK 784
Query: 347 LDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPPARLSWTRW 406
+ L V PP + Q V +G+ +LP C P + W R
Sbjct: 785 ITLDVGSPP-----VFIQEPADVSMEIGSNVTLP----------CYVQGYPEPTIKWRRL 829
Query: 407 GQTVGPSQPSD--------PGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSVH---Y 455
S+P G L + + +G + C A++ G +++V
Sbjct: 830 DNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVA 889
Query: 456 PPQLLGPSCSWEAEG--LHCSCSSQA-SPAPSLRWWLGEELLEGNSSQGSFEVTPSSAGP 512
P + PS + EG L C+ A +P P RW +L N +T S G
Sbjct: 890 PLIGISPSVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNP-----YITVRSDG- 943
Query: 513 WANSSLSLH---GGLSSGLRLRCKAWNVHGAQSGS---VFQLLPGKLEHG 556
SLH L G C A NV G + + V +LP ++HG
Sbjct: 944 ------SLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVLP-TIQHG 986
>gi|27735027 hypothetical protein LOC284369 [Homo sapiens]
Length = 197
Score = 84.0 bits (206), Expect = 4e-16
Identities = 57/147 (38%), Positives = 77/147 (52%), Gaps = 9/147 (6%)
Query: 456 PPQLLGPSCSWEAEGLHCSCSSQASPAPSLRWWLGEELLEGNSSQGSFEVTPSSAGPWAN 515
P +LL SCS E + L CSCS P PS++WW+G + + GS +VT + GPWAN
Sbjct: 9 PAKLLNSSCSLE-KTLQCSCSFHGIPTPSVQWWMGGVPVGVDGMDGSLQVTSTMLGPWAN 67
Query: 516 SSLSLHGGLSSGLRLRCKAWNVHGAQSGSVFQLLPGKLEHGG-----GLGLGAALGAGVA 570
S++SL G+RL C+ N +G + S+ L+ K GL GA V
Sbjct: 68 STISLTEEPEMGMRLLCEGKNQNGTHALSIL-LMSRKSSLAAQAFVKGLIQGAIYAGIVI 126
Query: 571 ALLAFCSCLVVFRVKICRKEARKRAAA 597
ALL CL+ VK RK+ K+AAA
Sbjct: 127 ALLFL--CLLPLIVKHIRKKQAKKAAA 151
>gi|239755187 PREDICTED: similar to hemicentin 2 [Homo sapiens]
Length = 1215
Score = 82.8 bits (203), Expect = 1e-15
Identities = 73/272 (26%), Positives = 113/272 (41%), Gaps = 35/272 (12%)
Query: 279 KGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLG-LELRGVRAGDSGRYTCRAE 337
+G +++ C+A P +SW + + L G L ++GV D+G Y+C+A
Sbjct: 504 QGVEVKVSCSASGYPTPHISWSRESQALQEDSRIHVDAQGTLIIQGVAPEDAGNYSCQAT 563
Query: 338 NRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSP 397
N +G+ Q+ + L PP VS N VL V G+ LVC P
Sbjct: 564 NEVGTDQETVTLYYTDPPS-----VSAVNAVVL----------VAVGEEAVLVCEASGVP 608
Query: 398 PARLSWTRWG-QTVGPSQPSDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSVHYP 456
P R+ W R G + + + S G L +P Q G +TC A + LG + L+V +
Sbjct: 609 PPRVIWYRGGLEMILAPEGSSSGKLRIPAAQERDAGTYTCRAVNELGDASAEIQLAVGHA 668
Query: 457 PQL--LGPSCSWE-AEGLHCSCSSQASPAPSLRWW------LGEELLEGNSSQGS----- 502
PQL L + E +C + P P++ W LG L G S+
Sbjct: 669 PQLTELPRDVTVELGRSALLACRATGRPPPTVTWRRGDGQPLGLRLGAGRGSRSRQPDSG 728
Query: 503 ---FE-VTPSSAGPWANSSLSLHGGLSSGLRL 530
FE V P P+ + ++ G + + RL
Sbjct: 729 VLFFESVAPEDQAPYVCEARNVFGKVQAEARL 760
Score = 65.5 bits (158), Expect = 2e-10
Identities = 76/290 (26%), Positives = 113/290 (38%), Gaps = 52/290 (17%)
Query: 217 PSPQDHDTDL-TCHVDFSRKGVSAQRTVRLRVAYAPKDLIISISHDNTSALELQGNVIYL 275
P+ Q+ D TC SA+ ++L V +AP+ + + D T
Sbjct: 636 PAAQERDAGTYTCRAVNELGDASAE--IQLAVGHAPQ--LTELPRDVT------------ 679
Query: 276 EVQKGQFLRLLCAADSQPPATLSWVLQDR--------VLSSSHPWGPRTLGLELRGVRAG 327
V+ G+ L C A +PP T++W D S P + L V
Sbjct: 680 -VELGRSALLACRATGRPPPTVTWRRGDGQPLGLRLGAGRGSRSRQPDSGVLFFESVAPE 738
Query: 328 DSGRYTCRAENRLGSQQQALDLSV--QYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQ 385
D Y C A N G Q L V PP+ ++ + TV VLEGQ
Sbjct: 739 DQAPYVCEARNVFGKVQAEARLIVTGHAPPQ-----IASSAPTVR----------VLEGQ 783
Query: 386 SLRLVCVTHSSPPA-RLSWTRWGQTVGPSQPSD---PGVLELPPIQMEHEGEFTCHAQHP 441
+ L C+ + P W + G+ + P G L L EH G ++C A +
Sbjct: 784 PVSLPCIVLAGRPLPERHWLKDGRPLPPGSRHSIRADGSLHLDRALQEHAGRYSCVATNT 843
Query: 442 LGSQHVSLSLSVHYPPQLLGPSCSWEA--EGLHCS--CSSQASPAPSLRW 487
GSQH + L V PP+ + P+ + EG+ S C + PAP++ W
Sbjct: 844 AGSQHRDVELVVQVPPR-IHPTATHHITNEGVPASLPCVASGVPAPTITW 892
Score = 65.1 bits (157), Expect = 2e-10
Identities = 73/286 (25%), Positives = 109/286 (38%), Gaps = 43/286 (15%)
Query: 277 VQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLGLELRGVRAGDSGRYTCRA 336
V G+ L+C A PP + W + + P G + L + + D+G YTCRA
Sbjct: 592 VAVGEEAVLVCEASGVPPPRVIWYRGGLEMILA-PEGSSSGKLRIPAAQERDAGTYTCRA 650
Query: 337 ENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSS 396
N LG + L+V + P+ +++ R V L G+S L C
Sbjct: 651 VNELGDASAEIQLAVGHAPQ-----LTELPRDVTVEL----------GRSALLACRATGR 695
Query: 397 PPARLSWTRW-GQTVG---------PSQPSDPGVLELPPIQMEHEGEFTCHAQHPLGSQH 446
PP ++W R GQ +G S+ D GVL + E + + C A++ G
Sbjct: 696 PPPTVTWRRGDGQPLGLRLGAGRGSRSRQPDSGVLFFESVAPEDQAPYVCEARNVFGKVQ 755
Query: 447 VSLSLSV--HYPPQLLGPSCS---WEAEGLHCSCSSQAS-PAPSLRWWLGEELLEGNS-S 499
L V H PPQ+ + + E + + C A P P W L +G
Sbjct: 756 AEARLIVTGHAPPQIASSAPTVRVLEGQPVSLPCIVLAGRPLPERHW-----LKDGRPLP 810
Query: 500 QGSFEVTPSSAGPWANSSLSLHGGLSSGLRLRCKAWNVHGAQSGSV 545
GS + + +L H G R C A N G+Q V
Sbjct: 811 PGSRHSIRADGSLHLDRALQEHAG-----RYSCVATNTAGSQHRDV 851
Score = 62.8 bits (151), Expect = 1e-09
Identities = 83/328 (25%), Positives = 124/328 (37%), Gaps = 58/328 (17%)
Query: 170 GQPVTVICVFNWAFKKCPAPSFSWTGAALSPRRTRPSTSHFSV-----LSFTPSPQDHDT 224
GQPV++ C+ P P W L R P S S+ L + Q+H
Sbjct: 782 GQPVSLPCI---VLAGRPLPERHW----LKDGRPLPPGSRHSIRADGSLHLDRALQEHAG 834
Query: 225 DLTCHVDFSRKGVSAQRTVRLRVAYAPKDLIISISHDNTSALELQGNVIYLEVQKGQFLR 284
+C + S R V L V P+ + + +H T+ +G
Sbjct: 835 RYSCVA--TNTAGSQHRDVELVVQVPPR-IHPTATHHITN--------------EGVPAS 877
Query: 285 LLCAADSQPPATLSWVLQDRVLSSSHP-WGPRTLG-LELRGVRAGDSGRYTCRAENRLGS 342
L C A P T++W + L+S P + G L + A D+G Y C A N +G
Sbjct: 878 LPCVASGVPAPTITWTKETNALTSRGPHYNVSKEGTLLIAQPSAQDAGAYVCTATNTVGF 937
Query: 343 QQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPPARLS 402
Q + LSV P R+ ++ + N + G+ + L C SPP ++
Sbjct: 938 SSQEMRLSVNTKP---RIHMNGSR-----NANVPLQVTAKAGEEVTLDCEAKGSPPPLVT 989
Query: 403 WTRWGQTVGPSQ------PSDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSVHYP 456
WT+ + V P PS G L L +Q+ G + C A +P GS L V
Sbjct: 990 WTKDSRPVPPITNRYGLLPS--GSLRLAQVQVGDSGHYECTASNPAGSASHRYVLGVQ-- 1045
Query: 457 PQLLGPSCSWEAEGL----HCSCSSQAS 480
SW+ + L H +C S S
Sbjct: 1046 -----GRTSWQPQSLPVPHHPACLSGLS 1068
Score = 57.8 bits (138), Expect = 3e-08
Identities = 58/235 (24%), Positives = 97/235 (41%), Gaps = 27/235 (11%)
Query: 277 VQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRT--LGLELRGVRAGDSGRYTC 334
V G+ L C + P L+WV RVL +S + L LE+ G+ D GRY C
Sbjct: 411 VSPGETAVLSCRVLGEAPYNLTWVRDWRVLPASTGRVAQLADLSLEISGIIPTDGGRYQC 470
Query: 335 RAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTH 394
A N G + ++ L V+ P+ V + + +S +G +++ C
Sbjct: 471 VASNANGVTRASVWLLVREAPQ---VSI------------HTSSQHFSQGVEVKVSCSAS 515
Query: 395 SSPPARLSWTRWGQTVGPS---QPSDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSL 451
P +SW+R Q + G L + + E G ++C A + +G+ +++L
Sbjct: 516 GYPTPHISWSRESQALQEDSRIHVDAQGTLIIQGVAPEDAGNYSCQATNEVGTDQETVTL 575
Query: 452 SVHYPPQLLGPSC---SWEAEGLHCSCSSQASPAPSLRWWLG--EELL--EGNSS 499
PP + + E C + P P + W+ G E +L EG+SS
Sbjct: 576 YYTDPPSVSAVNAVVLVAVGEEAVLVCEASGVPPPRVIWYRGGLEMILAPEGSSS 630
Score = 50.1 bits (118), Expect = 7e-06
Identities = 65/238 (27%), Positives = 102/238 (42%), Gaps = 31/238 (13%)
Query: 170 GQPVTVICVFNWAFKKCPAPSFSWTGA--ALSPRRTRPSTSHFSVLSFTPSPQDHDTDLT 227
G P ++ CV + PAP+ +WT AL+ R + S L P D
Sbjct: 873 GVPASLPCVASGV----PAPTITWTKETNALTSRGPHYNVSKEGTLLIA-QPSAQDAGAY 927
Query: 228 CHVDFSRKGVSAQRTVRLRVAYAPKDLIISISHDNTSALELQGNVIYLEVQKGQFLRLLC 287
+ G S+Q +RL V P+ I ++ + + LQ + + G+ + L C
Sbjct: 928 VCTATNTVGFSSQE-MRLSVNTKPR---IHMNGSRNANVPLQ-----VTAKAGEEVTLDC 978
Query: 288 AADSQPPATLSWVLQDR-VLSSSHPWGPRTLG-LELRGVRAGDSGRYTCRAENRLGSQQQ 345
A PP ++W R V ++ +G G L L V+ GDSG Y C A N GS
Sbjct: 979 EAKGSPPPLVTWTKDSRPVPPITNRYGLLPSGSLRLAQVQVGDSGHYECTASNPAGSASH 1038
Query: 346 ALDLSVQ----YPPENLRVMVSQANRTVLENLGNGTSLPVLE--GQSLRLVCVTHSSP 397
L VQ + P++L V A +G S+P+L+ +S+RL ++ +P
Sbjct: 1039 RYVLGVQGRTSWQPQSLPVPHHPA-------CLSGLSVPLLQPTPRSVRLCHLSLRAP 1089
Score = 43.5 bits (101), Expect = 7e-04
Identities = 56/210 (26%), Positives = 85/210 (40%), Gaps = 33/210 (15%)
Query: 321 LRGVRAGDSGRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLP 380
LR +A + G Y C A +R G+ + + V PP L V N T
Sbjct: 367 LRASKA-EEGTYECTAVSRAGTGRAKAQIVVTDPPPQL---VPAPNVT------------ 410
Query: 381 VLEGQSLRLVCVTHSSPPARLSWTR-W----GQTVGPSQPSDPGVLELPPIQMEHEGEFT 435
V G++ L C P L+W R W T +Q +D LE+ I G +
Sbjct: 411 VSPGETAVLSCRVLGEAPYNLTWVRDWRVLPASTGRVAQLADLS-LEISGIIPTDGGRYQ 469
Query: 436 CHAQHPLGSQHVSLSLSVHYPPQL-LGPSCSWEAEGLH--CSCSSQASPAPSLRWWLGEE 492
C A + G S+ L V PQ+ + S ++G+ SCS+ P P + W +
Sbjct: 470 CVASNANGVTRASVWLLVREAPQVSIHTSSQHFSQGVEVKVSCSASGYPTPHISWSRESQ 529
Query: 493 LLEGNS-----SQGSF---EVTPSSAGPWA 514
L+ +S +QG+ V P AG ++
Sbjct: 530 ALQEDSRIHVDAQGTLIIQGVAPEDAGNYS 559
>gi|94420689 neural cell adhesion molecule 1 isoform 1 [Homo
sapiens]
Length = 848
Score = 82.8 bits (203), Expect = 1e-15
Identities = 70/292 (23%), Positives = 119/292 (40%), Gaps = 45/292 (15%)
Query: 252 KDLIISISHDNTSALELQGNVIYLEVQKGQFLRLLCAADSQPPATLSWV-----LQDRVL 306
KD+ + ++ T ++ + N++ GQ + L+C A+ P T+SW ++
Sbjct: 202 KDIQVIVNVPPT--IQARQNIVNATANLGQSVTLVCDAEGFPEPTMSWTKDGEQIEQEED 259
Query: 307 SSSHPWGPRTLGLELRGVRAGDSGRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQAN 366
+ + + L ++ V D Y C AEN+ G Q + L V P+ V N
Sbjct: 260 DEKYIFSDDSSQLTIKKVDKNDEAEYICIAENKAGEQDATIHLKVFAKPKITYV----EN 315
Query: 367 RTVLENLGNGTSLPVLEGQSLRLVCVTHSSPPARLSWTRWGQTVGPSQPSDPG------- 419
+T +E LE Q + L C P ++W + + + + G
Sbjct: 316 QTAME----------LEEQ-VTLTCEASGDPIPSITWRTSTRNISSEEKTLDGHMVVRSH 364
Query: 420 ----VLELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSVHYPPQLLGPSC--SWEAEGLHC 473
L L IQ GE+ C A + +G S+ L V Y P+L GP +WE ++
Sbjct: 365 ARVSSLTLKSIQYTDAGEYICTASNTIGQDSQSMYLEVQYAPKLQGPVAVYTWEGNQVNI 424
Query: 474 SCSSQASPAPSLRWWLGEELLEGNS----------SQGSFEVTPSSAGPWAN 515
+C A P+ ++ W+ +LL ++ S EVTP S + N
Sbjct: 425 TCEVFAYPSATISWFRDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFGN 476
Score = 62.4 bits (150), Expect = 1e-09
Identities = 54/237 (22%), Positives = 97/237 (40%), Gaps = 48/237 (20%)
Query: 276 EVQKGQFLRLLCAADSQPPATLSWVLQDR-----------VLSSSHPWGPRTLGLELRGV 324
E ++G+ ++C S P T+ W + R VLS+++ L++RG+
Sbjct: 128 EFREGEDAVIVCDVVSSLPPTIIWKHKGRDVILKKDVRFIVLSNNY--------LQIRGI 179
Query: 325 RAGDSGRYTCRAENRLGSQQQA----LDLSVQYPPENLRVMVSQANRTVLENLGNGTSLP 380
+ D G Y C E R+ ++ + + + V PP QA + ++ N
Sbjct: 180 KKTDEGTYRC--EGRILARGEINFKDIQVIVNVPP------TIQARQNIVNATAN----- 226
Query: 381 VLEGQSLRLVCVTHSSPPARLSWTRWGQTVGPSQ-------PSDPGVLELPPIQMEHEGE 433
GQS+ LVC P +SWT+ G+ + + D L + + E E
Sbjct: 227 --LGQSVTLVCDAEGFPEPTMSWTKDGEQIEQEEDDEKYIFSDDSSQLTIKKVDKNDEAE 284
Query: 434 FTCHAQHPLGSQHVSLSLSVHYPPQLL---GPSCSWEAEGLHCSCSSQASPAPSLRW 487
+ C A++ G Q ++ L V P++ + E + +C + P PS+ W
Sbjct: 285 YICIAENKAGEQDATIHLKVFAKPKITYVENQTAMELEEQVTLTCEASGDPIPSITW 341
Score = 45.1 bits (105), Expect = 2e-04
Identities = 63/245 (25%), Positives = 95/245 (38%), Gaps = 39/245 (15%)
Query: 113 SCSLVIRDAQREDEAWYFFRVERGSRVRHSFLSNAFFLKVTALTKKPDVYIPETLEPGQP 172
S L I+ + DEA Y E + + + + LKV A K V +E +
Sbjct: 269 SSQLTIKKVDKNDEAEYICIAENKAGEQDATIH----LKVFAKPKITYVENQTAMELEEQ 324
Query: 173 VTVICVFNWAFKKCPAPSFSW---TGAALSPRRTRPS----TSHFSVLSFTPSPQDHDTD 225
VT+ C + P PS +W T S +T SH V S T + TD
Sbjct: 325 VTLTCEASGD----PIPSITWRTSTRNISSEEKTLDGHMVVRSHARVSSLTLKSIQY-TD 379
Query: 226 LTCHVDFSRKGVSAQ-RTVRLRVAYAPKDLIISISHDNTSALELQGNVIYLEVQKGQFLR 284
++ + + +++ L V YAPK LQG V + +G +
Sbjct: 380 AGEYICTASNTIGQDSQSMYLEVQYAPK---------------LQGPVA-VYTWEGNQVN 423
Query: 285 LLCAADSQPPATLSWVLQDRVLSSSHPWG------PRTLGLELRGVRAGDSGRYTCRAEN 338
+ C + P AT+SW ++L SS+ P LE+ D G Y C A N
Sbjct: 424 ITCEVFAYPSATISWFRDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFGNYNCTAVN 483
Query: 339 RLGSQ 343
R+G +
Sbjct: 484 RIGQE 488
>gi|115529478 neural cell adhesion molecule 1 isoform 3 [Homo
sapiens]
Length = 761
Score = 82.8 bits (203), Expect = 1e-15
Identities = 70/292 (23%), Positives = 119/292 (40%), Gaps = 45/292 (15%)
Query: 252 KDLIISISHDNTSALELQGNVIYLEVQKGQFLRLLCAADSQPPATLSWV-----LQDRVL 306
KD+ + ++ T ++ + N++ GQ + L+C A+ P T+SW ++
Sbjct: 202 KDIQVIVNVPPT--IQARQNIVNATANLGQSVTLVCDAEGFPEPTMSWTKDGEQIEQEED 259
Query: 307 SSSHPWGPRTLGLELRGVRAGDSGRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQAN 366
+ + + L ++ V D Y C AEN+ G Q + L V P+ V N
Sbjct: 260 DEKYIFSDDSSQLTIKKVDKNDEAEYICIAENKAGEQDATIHLKVFAKPKITYV----EN 315
Query: 367 RTVLENLGNGTSLPVLEGQSLRLVCVTHSSPPARLSWTRWGQTVGPSQPSDPG------- 419
+T +E LE Q + L C P ++W + + + + G
Sbjct: 316 QTAME----------LEEQ-VTLTCEASGDPIPSITWRTSTRNISSEEKTLDGHMVVRSH 364
Query: 420 ----VLELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSVHYPPQLLGPSC--SWEAEGLHC 473
L L IQ GE+ C A + +G S+ L V Y P+L GP +WE ++
Sbjct: 365 ARVSSLTLKSIQYTDAGEYICTASNTIGQDSQSMYLEVQYAPKLQGPVAVYTWEGNQVNI 424
Query: 474 SCSSQASPAPSLRWWLGEELLEGNS----------SQGSFEVTPSSAGPWAN 515
+C A P+ ++ W+ +LL ++ S EVTP S + N
Sbjct: 425 TCEVFAYPSATISWFRDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFGN 476
Score = 62.4 bits (150), Expect = 1e-09
Identities = 54/237 (22%), Positives = 97/237 (40%), Gaps = 48/237 (20%)
Query: 276 EVQKGQFLRLLCAADSQPPATLSWVLQDR-----------VLSSSHPWGPRTLGLELRGV 324
E ++G+ ++C S P T+ W + R VLS+++ L++RG+
Sbjct: 128 EFREGEDAVIVCDVVSSLPPTIIWKHKGRDVILKKDVRFIVLSNNY--------LQIRGI 179
Query: 325 RAGDSGRYTCRAENRLGSQQQA----LDLSVQYPPENLRVMVSQANRTVLENLGNGTSLP 380
+ D G Y C E R+ ++ + + + V PP QA + ++ N
Sbjct: 180 KKTDEGTYRC--EGRILARGEINFKDIQVIVNVPP------TIQARQNIVNATAN----- 226
Query: 381 VLEGQSLRLVCVTHSSPPARLSWTRWGQTVGPSQ-------PSDPGVLELPPIQMEHEGE 433
GQS+ LVC P +SWT+ G+ + + D L + + E E
Sbjct: 227 --LGQSVTLVCDAEGFPEPTMSWTKDGEQIEQEEDDEKYIFSDDSSQLTIKKVDKNDEAE 284
Query: 434 FTCHAQHPLGSQHVSLSLSVHYPPQLL---GPSCSWEAEGLHCSCSSQASPAPSLRW 487
+ C A++ G Q ++ L V P++ + E + +C + P PS+ W
Sbjct: 285 YICIAENKAGEQDATIHLKVFAKPKITYVENQTAMELEEQVTLTCEASGDPIPSITW 341
Score = 45.1 bits (105), Expect = 2e-04
Identities = 63/245 (25%), Positives = 95/245 (38%), Gaps = 39/245 (15%)
Query: 113 SCSLVIRDAQREDEAWYFFRVERGSRVRHSFLSNAFFLKVTALTKKPDVYIPETLEPGQP 172
S L I+ + DEA Y E + + + + LKV A K V +E +
Sbjct: 269 SSQLTIKKVDKNDEAEYICIAENKAGEQDATIH----LKVFAKPKITYVENQTAMELEEQ 324
Query: 173 VTVICVFNWAFKKCPAPSFSW---TGAALSPRRTRPS----TSHFSVLSFTPSPQDHDTD 225
VT+ C + P PS +W T S +T SH V S T + TD
Sbjct: 325 VTLTCEASGD----PIPSITWRTSTRNISSEEKTLDGHMVVRSHARVSSLTLKSIQY-TD 379
Query: 226 LTCHVDFSRKGVSAQ-RTVRLRVAYAPKDLIISISHDNTSALELQGNVIYLEVQKGQFLR 284
++ + + +++ L V YAPK LQG V + +G +
Sbjct: 380 AGEYICTASNTIGQDSQSMYLEVQYAPK---------------LQGPVA-VYTWEGNQVN 423
Query: 285 LLCAADSQPPATLSWVLQDRVLSSSHPWG------PRTLGLELRGVRAGDSGRYTCRAEN 338
+ C + P AT+SW ++L SS+ P LE+ D G Y C A N
Sbjct: 424 ITCEVFAYPSATISWFRDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFGNYNCTAVN 483
Query: 339 RLGSQ 343
R+G +
Sbjct: 484 RIGQE 488
>gi|109150416 peroxidasin [Homo sapiens]
Length = 1479
Score = 82.8 bits (203), Expect = 1e-15
Identities = 76/287 (26%), Positives = 123/287 (42%), Gaps = 48/287 (16%)
Query: 276 EVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTL-----GLELRGVRAGDSG 330
EV G+ + L C+A PP +SW DR + P PR GL ++ V GDSG
Sbjct: 352 EVLVGESVTLECSATGHPPPRISWTRGDR---TPLPVDPRVNITPSGGLYIQNVVQGDSG 408
Query: 331 RYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLV 390
Y C A N + S + VQ P+ V+ +R V+E GQ++
Sbjct: 409 EYACSATNNIDSVHATAFIIVQALPQ---FTVTPQDRVVIE------------GQTVDFQ 453
Query: 391 CVTHSSPPARLSWTRWGQTVGPSQPS---DPGVLELPPIQMEHEGEFTCHAQHPLGSQHV 447
C +PP ++WT+ G + + G L + + + +G++ C A + +GSQ V
Sbjct: 454 CEAKGNPPPVIAWTKGGSQLSVDRRHLVLSSGTLRISGVALHDQGQYECQAVNIIGSQKV 513
Query: 448 SLSLSVHYPPQLLGPSCSWEAE-------GLHCSCSSQASPAPSLRWWL-GEELLEGNSS 499
L+V P++ S ++ + CSSQ P P++ W G ++ E
Sbjct: 514 VAHLTVQ--PRVTPVFASIPSDTTVEVGANVQLPCSSQGEPEPAITWNKDGVQVTE---- 567
Query: 500 QGSFEVTPSSAGPWANSSLSLHG-GLSSGLRLRCKAWNVHGAQSGSV 545
G F ++P L+++ G + R C A N G+ S S+
Sbjct: 568 SGKFHISP-------EGFLTINDVGPADAGRYECVARNTIGSASVSM 607
Score = 70.1 bits (170), Expect = 7e-12
Identities = 98/407 (24%), Positives = 158/407 (38%), Gaps = 49/407 (12%)
Query: 57 SYPRDGWDESTAAYGYWFKGRTSPKTGAPVATNNQSREVEMSTRDRFQLTGDPGKGSCSL 116
S P+D + T+ +F R + + E+ M T R L D +L
Sbjct: 250 SEPQDA--DVTSGNTVYFTCRAEGNPKPEIIWLRNNNELSMKTDSRLNLLDDG-----TL 302
Query: 117 VIRDAQREDEAWYFFRVERGSRVRHSFLSNAFFLKVTALTKKPDVYI-PETLEP--GQPV 173
+I++ Q D+ Y + V + L+ +P I P+ E G+ V
Sbjct: 303 MIQNTQETDQGIYQCMAKN---VAGEVKTQEVTLRYFGSPARPTFVIQPQNTEVLVGESV 359
Query: 174 TVICVFNWAFKKCPAPSFSWTGAALSPRRTRPSTSHFSVLSFTPSPQDHDTDLTCHVDFS 233
T+ C + P P SWT +P P ++ TPS + ++ D
Sbjct: 360 TLEC----SATGHPPPRISWTRGDRTPLPVDPR------VNITPSGGLYIQNVV-QGDSG 408
Query: 234 RKGVSAQRTVRLRVAYAPKDLIISISHDNTSALELQGNVIYLEVQKGQFLRLLCAADSQP 293
SA T + +A +I+ T + Q V+ +GQ + C A P
Sbjct: 409 EYACSA--TNNIDSVHATAFIIVQALPQFT--VTPQDRVVI----EGQTVDFQCEAKGNP 460
Query: 294 PATLSWVLQDRVLSSSHPWGPRTLG-LELRGVRAGDSGRYTCRAENRLGSQQQALDLSVQ 352
P ++W LS + G L + GV D G+Y C+A N +GSQ+ L+VQ
Sbjct: 461 PPVIAWTKGGSQLSVDRRHLVLSSGTLRISGVALHDQGQYECQAVNIIGSQKVVAHLTVQ 520
Query: 353 YPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPPARLSWTRWGQTV-- 410
P V S + T +E G +++L C + P ++W + G V
Sbjct: 521 --PRVTPVFASIPSDTTVE-----------VGANVQLPCSSQGEPEPAITWNKDGVQVTE 567
Query: 411 -GPSQPSDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSVHYP 456
G S G L + + G + C A++ +GS VS+ LSV+ P
Sbjct: 568 SGKFHISPEGFLTINDVGPADAGRYECVARNTIGSASVSMVLSVNVP 614
Score = 68.2 bits (165), Expect = 3e-11
Identities = 71/276 (25%), Positives = 109/276 (39%), Gaps = 30/276 (10%)
Query: 276 EVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLG---LELRGVRAGDSGRY 332
+V G + C A+ P + W+ + LS L L ++ + D G Y
Sbjct: 256 DVTSGNTVYFTCRAEGNPKPEIIWLRNNNELSMKTDSRLNLLDDGTLMIQNTQETDQGIY 315
Query: 333 TCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCV 392
C A+N G V+ LR S A T + N VL G+S+ L C
Sbjct: 316 QCMAKNVAGE--------VKTQEVTLRYFGSPARPTFVIQPQN---TEVLVGESVTLECS 364
Query: 393 THSSPPARLSWTRWGQTVGPSQP----SDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVS 448
PP R+SWTR +T P P + G L + + GE+ C A + + S H +
Sbjct: 365 ATGHPPPRISWTRGDRTPLPVDPRVNITPSGGLYIQNVVQGDSGEYACSATNNIDSVHAT 424
Query: 449 LSLSVHYPPQL-LGPSCSWEAEG--LHCSCSSQASPAPSLRWWLGEELLEGNSSQGSFEV 505
+ V PQ + P EG + C ++ +P P + W G G+
Sbjct: 425 AFIIVQALPQFTVTPQDRVVIEGQTVDFQCEAKGNPPPVIAWTKG-----GSQLSVDRRH 479
Query: 506 TPSSAGPWANSSLSLHGGLSSGLRLRCKAWNVHGAQ 541
S+G S ++LH G + C+A N+ G+Q
Sbjct: 480 LVLSSGTLRISGVALH---DQG-QYECQAVNIIGSQ 511
>gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens]
Length = 4391
Score = 80.5 bits (197), Expect = 5e-15
Identities = 103/460 (22%), Positives = 176/460 (38%), Gaps = 78/460 (16%)
Query: 116 LVIRDAQREDEAWY------FFRVERGSRVRHSFLSNAFFLKVTALTKKPDVYIPE-TLE 168
L IR+ Q D Y F +++G+ H S V + ++ P+ T++
Sbjct: 1825 LTIRNVQLSDAGTYVCTGSNMFAMDQGTATLHVQASGTLSAPVVS------IHPPQLTVQ 1878
Query: 169 PGQPVTVICVFNWAFKKCPAPSFSWTGAALSPRRTRPSTS--HFSVLSFTPSPQDHDTDL 226
PGQ + F + P P+ WTG P P+ + H +L
Sbjct: 1879 PGQ----LAEFRCSATGSPTPTLEWTGG---PGGQLPAKAQIHGGILRLPAVEPTDQAQY 1931
Query: 227 TCHVDFSRKGVSAQRTVRLRVAYAPKDLIISISHDNTSALELQGNVIYLEVQKGQFLRLL 286
C S A+ + + P+ + +S + T +V G+ +RL
Sbjct: 1932 LCRAHSSAGQQVARAVLHVHGGGGPR---VQVSPERT------------QVHAGRTVRLY 1976
Query: 287 CAADSQPPATLSWVLQDRVLSSSHPWGPRT-----LGLELRGVRAGDSGRYTCRAENRLG 341
C A P AT++W R S P R+ L + + D+G Y C A + G
Sbjct: 1977 CRAAGVPSATITW----RKEGGSLPPQARSERTDIATLLIPAITTADAGFYLCVATSPAG 2032
Query: 342 SQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPPARL 401
+ Q + + V++S ++ + +S V EGQ+L L CV S A++
Sbjct: 2033 TAQARIQV----------VVLSASDASPPPVKIESSSPSVTEGQTLDLNCVVAGSAHAQV 2082
Query: 402 SWTRWGQTVGPSQPSDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSVHY------ 455
+W R G ++ P L LP + GE+ C ++ G + S+++SV +
Sbjct: 2083 TWYRRGGSLPPHTQVHGSRLRLPQVSPADSGEYVCRVENGSGPKEASITVSVLHGTHSGP 2142
Query: 456 ---------PPQLLGPSCSWEAEG--LHCSCSSQASPAPSLRWW-LGEELLEGNSSQGSF 503
P + PS S AEG L +C + W G L + + GS
Sbjct: 2143 SYTPVPGSTRPIRIEPSSSHVAEGQTLDLNCVVPGQAHAQVTWHKRGGSLPARHQTHGSL 2202
Query: 504 ----EVTPSSAGPWANSSLSLHGGLSSGLRLRCKAWNVHG 539
+VTP+ +G + + G L + + + +A + G
Sbjct: 2203 LRLHQVTPADSGEYVCHVVGTSGPLEASVLVTIEASVIPG 2242
Score = 75.5 bits (184), Expect = 2e-13
Identities = 63/225 (28%), Positives = 85/225 (37%), Gaps = 20/225 (8%)
Query: 274 YLEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLGLELRGVRAG--DSGR 331
+ VQ G+ ++L C A PP T W RV SS P L RA DSGR
Sbjct: 3307 HASVQAGETVQLQCLAHGTPPLTFQW---SRV-GSSLPGRATARNELLHFERAAPEDSGR 3362
Query: 332 YTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLE----GQSL 387
Y CR N++GS + L VQ PP +L A T + P LE G S+
Sbjct: 3363 YRCRVTNKVGSAEAFAQLLVQGPPGSLPATSIPAGSTPTVQV-----TPQLETKSIGASV 3417
Query: 388 RLVCVTHSSPPARLSWTRWGQTVGPSQPSDPGVLELPPIQMEHEGEFTCHAQHPLGSQHV 447
C S +L W + G + P GVL + + +G + C A P G
Sbjct: 3418 EFHCAVPSDRGTQLRWFKEGGQLPPGHSVQDGVLRIQNLDQSCQGTYICQAHGPWGKAQA 3477
Query: 448 SLSLSVHYPPQLL-----GPSCSWEAEGLHCSCSSQASPAPSLRW 487
S L + P +L + C + P P + W
Sbjct: 3478 SAQLVIQALPSVLINIRTSVQTVVVGHAVEFECLALGDPKPQVTW 3522
Score = 73.9 bits (180), Expect = 5e-13
Identities = 75/302 (24%), Positives = 119/302 (39%), Gaps = 44/302 (14%)
Query: 164 PETLEPGQPVTVICVFNWAFKKCPAPSFSWTGAALSPRRTRPST-----SHFSVLSFTPS 218
P ++ G+ VT+ CV P S WT + +P + T SH + +
Sbjct: 3121 PVWVKVGKAVTLECVSAGE----PRSSARWTRISSTPAKLEQRTYGLMDSHAVLQISSAK 3176
Query: 219 PQDHDTDLTCHVDFSRKGV-SAQRTVRLRVAYAPKDLIISISHDNTSALELQGNVIYLEV 277
P D T +V ++ + +AQ+ V ++I+ A ++Q L V
Sbjct: 3177 PSDAGT----YVCLAQNALGTAQKQV---------EVIVDTGAMAPGAPQVQAEEAELTV 3223
Query: 278 QKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLG--LELRGVRAGDSGRYTCR 335
+ G L C+A P T+ W L S PW R G L + V DSG+Y C
Sbjct: 3224 EAGHTATLRCSATGSPAPTIHW----SKLRSPLPWQHRLEGDTLIIPRVAQQDSGQYICN 3279
Query: 336 AENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHS 395
A + G + + L V+ PP TV E+ V G++++L C+ H
Sbjct: 3280 ATSPAGHAEATIILHVESPPYAT---------TVPEHAS------VQAGETVQLQCLAHG 3324
Query: 396 SPPARLSWTRWGQTVGPSQPSDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSVHY 455
+PP W+R G ++ + +L E G + C + +GS L V
Sbjct: 3325 TPPLTFQWSRVGSSLPGRATARNELLHFERAAPEDSGRYRCRVTNKVGSAEAFAQLLVQG 3384
Query: 456 PP 457
PP
Sbjct: 3385 PP 3386
Score = 71.6 bits (174), Expect = 2e-12
Identities = 74/299 (24%), Positives = 122/299 (40%), Gaps = 30/299 (10%)
Query: 256 ISISHDNTSALELQGNVIYLEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPR 315
+S SH A ++ + G L L C SQ P T++W + L S H +
Sbjct: 2524 LSGSHSQGVAYPVRIESSSASLANGHTLDLNCLVASQAPHTITWYKRGGSLPSRH----Q 2579
Query: 316 TLGLELR--GVRAGDSGRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENL 373
+G LR V DSG Y C N GS++ +L +++Q + VS R
Sbjct: 2580 IVGSRLRIPQVTPADSGEYVCHVSNGAGSRETSLIVTIQGSGSSHVPSVSPPIRI----- 2634
Query: 374 GNGTSLPVLEGQSLRLVCVTHSSPPARLSWTRWGQTVGPSQPSDPGVLELPPIQMEHEGE 433
+S V+EGQ+L L CV P A ++W + G ++ + L L + + GE
Sbjct: 2635 -ESSSPTVVEGQTLDLNCVVARQPQAIITWYKRGGSLPSRHQTHGSHLRLHQMSVADSGE 2693
Query: 434 FTCHAQHPLGSQHVSLSLSV-----------HYPPQLLGPSCSWEAEG--LHCSCSSQAS 480
+ C A + + + S+ +SV P + S S AEG L +C
Sbjct: 2694 YVCRANNNIDALEASIVISVSPSAGSPSAPGSSMPIRIESSSSHVAEGETLDLNCVVPGQ 2753
Query: 481 PAPSLRWW-LGEELLEGNSSQGS----FEVTPSSAGPWANSSLSLHGGLSSGLRLRCKA 534
+ W G L + ++GS V+P+ +G + + G L + + + +A
Sbjct: 2754 AHAQVTWHKRGGSLPSHHQTRGSRLRLHHVSPADSGEYVCRVMGSSGPLEASVLVTIEA 2812
Score = 68.2 bits (165), Expect = 3e-11
Identities = 62/253 (24%), Positives = 101/253 (39%), Gaps = 35/253 (13%)
Query: 256 ISISHDNTSALELQGNVIYLE-----VQKGQFLRLLCAA-DSQPPATLSWVLQDRVLSSS 309
+++ S+ L+ VI ++ VQ+GQ C D P +L W +++ L +
Sbjct: 3007 VTVPPSEGSSYRLRSPVISIDPPSSTVQQGQDASFKCLIHDGAAPISLEWKTRNQELEDN 3066
Query: 310 HPWGPRTLGLELRGVRAGDSGRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTV 369
P + + G R + G Y C A N G Q ++LSV PP
Sbjct: 3067 VHISPNGSIITIVGTRPSNHGTYRCVASNAYGVAQSVVNLSVHGPP-------------T 3113
Query: 370 LENLGNGTSLPVLEGQSLRLVCVTHSSPPARLSWTRWGQTVGPSQPSDPG------VLEL 423
+ L G + V G+++ L CV+ P + WTR T + G VL++
Sbjct: 3114 VSVLPEG-PVWVKVGKAVTLECVSAGEPRSSARWTRISSTPAKLEQRTYGLMDSHAVLQI 3172
Query: 424 PPIQMEHEGEFTCHAQHPLGSQHVSLSLSVHY------PPQLLGPSCSWEAEGLHCS--- 474
+ G + C AQ+ LG+ + + V PQ+ E H +
Sbjct: 3173 SSAKPSDAGTYVCLAQNALGTAQKQVEVIVDTGAMAPGAPQVQAEEAELTVEAGHTATLR 3232
Query: 475 CSSQASPAPSLRW 487
CS+ SPAP++ W
Sbjct: 3233 CSATGSPAPTIHW 3245
Score = 58.2 bits (139), Expect = 3e-08
Identities = 74/292 (25%), Positives = 114/292 (39%), Gaps = 36/292 (12%)
Query: 277 VQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHP-WGPRTLGLELRGVRAGDSGRYTCR 335
V +GQ L L C Q A ++W + L + H GP L L V DSG Y+C+
Sbjct: 2838 VAEGQTLDLKCVVPGQAHAQVTWHKRGGNLPARHQVHGPL---LRLNQVSPADSGEYSCQ 2894
Query: 336 AENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHS 395
G+ + ++ ++++ A +E +S V EGQ+L L CV
Sbjct: 2895 VTGSSGTLEASVLVTIEPSSPGPIPAPGLAQPIYIE----ASSSHVTEGQTLDLNCVVPG 2950
Query: 396 SPPARLSWTRWGQTVGPSQPSDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSVHY 455
A+++W + G ++ + L L + GE+ C A G + S +V
Sbjct: 2951 QAHAQVTWYKRGGSLPARHQTHGSQLRLHLVSPADSGEYVCRAASGPGPEQ-EASFTVTV 3009
Query: 456 PPQ------------LLGPSCSWEAEGLHCS--CSSQASPAP-SLRWWLGEELLEGN--- 497
PP + P S +G S C AP SL W + LE N
Sbjct: 3010 PPSEGSSYRLRSPVISIDPPSSTVQQGQDASFKCLIHDGAAPISLEWKTRNQELEDNVHI 3069
Query: 498 SSQGSF----EVTPSSAGPWANSSLSLHGGLSSGLRLRCKAWNVHGAQSGSV 545
S GS PS+ G + + + +G S + L +VHG + SV
Sbjct: 3070 SPNGSIITIVGTRPSNHGTYRCVASNAYGVAQSVVNL-----SVHGPPTVSV 3116
Score = 58.2 bits (139), Expect = 3e-08
Identities = 70/332 (21%), Positives = 129/332 (38%), Gaps = 34/332 (10%)
Query: 163 IPE--TLEPGQPVTVICVFNWAFKKCPAPSFSWT--GAALSPRRTRPSTSHFSVLSFTPS 218
+PE +++ G+ V + C+ + P +F W+ G++L R +T+ +L F +
Sbjct: 3304 VPEHASVQAGETVQLQCLAHGT----PPLTFQWSRVGSSLPGR----ATARNELLHFERA 3355
Query: 219 PQDHDTDLTCHVDFSRKGVSAQRTVRLRVAYAPKDL-IISISHDNTSALELQGNVIYLEV 277
+ C V + K SA+ +L V P L SI +T +++ + +
Sbjct: 3356 APEDSGRYRCRV--TNKVGSAEAFAQLLVQGPPGSLPATSIPAGSTPTVQVTPQLETKSI 3413
Query: 278 QKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLGLELRGVRAGDSGRYTCRAE 337
G + CA S L W + L H L ++ + G Y C+A
Sbjct: 3414 --GASVEFHCAVPSDRGTQLRWFKEGGQLPPGHSVQDGVL--RIQNLDQSCQGTYICQAH 3469
Query: 338 NRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSP 397
G Q + L +Q P +VL N+ V+ G ++ C+ P
Sbjct: 3470 GPWGKAQASAQLVIQALP------------SVLINIRTSVQTVVV-GHAVEFECLALGDP 3516
Query: 398 PARLSWTRWGQTVGPSQPSDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSVHYPP 457
+++W++ G + P GV+ + +++ G++ C A + G+ + L V P
Sbjct: 3517 KPQVTWSKVGGHLRPGIVQSGGVVRIAHVELADAGQYRCTATNAAGTTQSHVLLLVQALP 3576
Query: 458 QLLGPSCSWEAEGLHC--SCSSQASPAPSLRW 487
Q+ P G C + P P + W
Sbjct: 3577 QISMPQEVRVPAGSAAVFPCIASGYPTPDISW 3608
Score = 53.1 bits (126), Expect = 8e-07
Identities = 53/222 (23%), Positives = 76/222 (34%), Gaps = 21/222 (9%)
Query: 277 VQKGQFLRLLCAADSQPPATLSWVLQD-RVLSSSHPWGPRTLGLELRGVRAGDSGRYTCR 335
V +G L C PP W +D R + S + L V+ D+G Y C
Sbjct: 1688 VPQGGSHSLRCQVSGSPPHYFYWSREDGRPVPSGTQQRHQGSELHFPSVQPSDAGVYICT 1747
Query: 336 AENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHS 395
N S +L V P + + R S V G + +C S
Sbjct: 1748 CRNLHQSNTSRAELLVTEAPSKPITVTVEEQR----------SQSVRPGADVTFICTAKS 1797
Query: 396 SPPA-RLSWTRWGQTVGPSQPSD-PGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSV 453
PA L WTR P++ D G+L + +Q+ G + C + + +L V
Sbjct: 1798 KSPAYTLVWTRLHNGKLPTRAMDFNGILTIRNVQLSDAGTYVCTGSNMFAMDQGTATLHV 1857
Query: 454 HYPPQLLGPSCSWEAEGL--------HCSCSSQASPAPSLRW 487
L P S L CS+ SP P+L W
Sbjct: 1858 QASGTLSAPVVSIHPPQLTVQPGQLAEFRCSATGSPTPTLEW 1899
Score = 52.4 bits (124), Expect = 1e-06
Identities = 44/186 (23%), Positives = 76/186 (40%), Gaps = 6/186 (3%)
Query: 277 VQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLGLELRGVRAGDSGRYTCRA 336
V +G+ L L C Q A ++W + L S H R L L V DSG Y CR
Sbjct: 2738 VAEGETLDLNCVVPGQAHAQVTWHKRGGSLPSHHQ--TRGSRLRLHHVSPADSGEYVCRV 2795
Query: 337 ENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSS 396
G + ++ ++++ + + + + +S V EGQ+L L CV
Sbjct: 2796 MGSSGPLEASVLVTIEASGSSAVHVPAPGGAPPIRI--EPSSSRVAEGQTLDLKCVVPGQ 2853
Query: 397 PPARLSWTRWGQTVGPSQPSDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSVHYP 456
A+++W + G + +L L + GE++C G+ S+ +++
Sbjct: 2854 AHAQVTWHKRGGNLPARHQVHGPLLRLNQVSPADSGEYSCQVTGSSGTLEASVLVTIE-- 2911
Query: 457 PQLLGP 462
P GP
Sbjct: 2912 PSSPGP 2917
Score = 50.1 bits (118), Expect = 7e-06
Identities = 78/305 (25%), Positives = 117/305 (38%), Gaps = 55/305 (18%)
Query: 276 EVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLGLELRGVRAG--DSGRYT 333
+V +GQ L L C Q A ++W + L H +T G LR +A DSG Y
Sbjct: 2351 QVAEGQTLDLNCVVPGQSHAQVTWHKRGGSLPVRH----QTHGSLLRLYQASPADSGEYV 2406
Query: 334 CRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLG-------NGTSLPVLEGQS 386
CR LGS P V+V+ + LG +S V EGQ+
Sbjct: 2407 CRV---LGSSV----------PLEASVLVTIEPAGSVPALGVTPTVRIESSSSQVAEGQT 2453
Query: 387 LRLVCVTHSSPPARLSWTRWGQTVGPSQPSDPGVLELPPIQMEHEGEFTCHAQHPLGSQH 446
L L C+ A+++W + G ++ L L + GE+ C G+Q
Sbjct: 2454 LDLNCLVAGQAHAQVTWHKRGGSLPARHQVHGSRLRLLQVTPADSGEYVCRVVGSSGTQE 2513
Query: 447 VSL------------SLSVHYPPQLLGPSCSWEAEG----LHCSCSSQASPAPSLRWW-L 489
S+ S V YP ++ S S A G L+C +SQA ++ W+
Sbjct: 2514 ASVLVTIQQRLSGSHSQGVAYPVRIESSSASL-ANGHTLDLNCLVASQA--PHTITWYKR 2570
Query: 490 GEELLEGNSSQGSF----EVTPSSAGPWANSSLSLHGGLSSGLRLRCKAWNVHGAQSGSV 545
G L + GS +VTP+ +G + H +G R + G+ S V
Sbjct: 2571 GGSLPSRHQIVGSRLRIPQVTPADSGEYV-----CHVSNGAGSRETSLIVTIQGSGSSHV 2625
Query: 546 FQLLP 550
+ P
Sbjct: 2626 PSVSP 2630
Score = 48.1 bits (113), Expect = 3e-05
Identities = 69/311 (22%), Positives = 122/311 (39%), Gaps = 52/311 (16%)
Query: 238 SAQRTVRLRVAYAPKDLIISIS-----HDNTSALELQGNVIYLEVQ-------KGQFLRL 285
S + R+ PK+ I++S H S + G+ + ++ +GQ L L
Sbjct: 2112 SGEYVCRVENGSGPKEASITVSVLHGTHSGPSYTPVPGSTRPIRIEPSSSHVAEGQTLDL 2171
Query: 286 LCAADSQPPATLSWVLQDRVLSSSHPWGPRTLG--LELRGVRAGDSGRYTCRAENRLGSQ 343
C Q A ++W + L + H +T G L L V DSG Y C G
Sbjct: 2172 NCVVPGQAHAQVTWHKRGGSLPARH----QTHGSLLRLHQVTPADSGEYVCHVVGTSGPL 2227
Query: 344 QQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPPARLSW 403
+ ++ ++++ V+ +E+ +S V EGQ+L L CV A+++W
Sbjct: 2228 EASVLVTIE-----ASVIPGPIPPVRIES----SSSTVAEGQTLDLSCVVAGQAHAQVTW 2278
Query: 404 TRWGQTVGPSQPSDPGVLELPPIQMEHEGEFTCHAQHPL---------GSQHVSLSLSVH 454
+ G ++ L + G++ C A + + G+Q +L+
Sbjct: 2279 YKRGGSLPARHQVRGSRLYIFQASPADAGQYVCRASNGMEASITVTVTGTQGANLA---- 2334
Query: 455 YP-----PQLLGPSCSWEAEG--LHCSCSSQASPAPSLRWW-LGEELLEGNSSQGS---- 502
YP P + PS S AEG L +C + W G L + + GS
Sbjct: 2335 YPAGSTQPIRIEPSSSQVAEGQTLDLNCVVPGQSHAQVTWHKRGGSLPVRHQTHGSLLRL 2394
Query: 503 FEVTPSSAGPW 513
++ +P+ +G +
Sbjct: 2395 YQASPADSGEY 2405
Score = 47.8 bits (112), Expect = 4e-05
Identities = 77/321 (23%), Positives = 115/321 (35%), Gaps = 56/321 (17%)
Query: 277 VQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLGLELRGVRAGDSGRYTCRA 336
V +GQ L L C Q A ++W + L + H R L + D+G+Y CRA
Sbjct: 2256 VAEGQTLDLSCVVAGQAHAQVTWYKRGGSLPARHQ--VRGSRLYIFQASPADAGQYVCRA 2313
Query: 337 ENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSS 396
N + + Q NL +E +S V EGQ+L L CV
Sbjct: 2314 SNGMEASITVTVTGTQ--GANLAYPAGSTQPIRIEP----SSSQVAEGQTLDLNCVVPGQ 2367
Query: 397 PPARLSWTRWGQTVGPSQPSDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSVHY- 455
A+++W + G ++ + +L L GE+ C LGS V L SV
Sbjct: 2368 SHAQVTWHKRGGSLPVRHQTHGSLLRLYQASPADSGEYVCRV---LGSS-VPLEASVLVT 2423
Query: 456 -------------PPQLLGPSCSWEAEG----LHCSCSSQASPAPSLRWW-LGEELLEGN 497
P + S S AEG L+C + QA + W G L +
Sbjct: 2424 IEPAGSVPALGVTPTVRIESSSSQVAEGQTLDLNCLVAGQAH--AQVTWHKRGGSLPARH 2481
Query: 498 SSQGS----FEVTPSSAGPWANSSLSLHGGLSSGLRLRCKAWNVHGAQSGSVFQLLPGKL 553
GS +VTP+ +G + C+ G Q SV + +L
Sbjct: 2482 QVHGSRLRLLQVTPADSGEYV-----------------CRVVGSSGTQEASVLVTIQQRL 2524
Query: 554 --EHGGGLGLGAALGAGVAAL 572
H G+ + + A+L
Sbjct: 2525 SGSHSQGVAYPVRIESSSASL 2545
Score = 43.1 bits (100), Expect = 9e-04
Identities = 39/175 (22%), Positives = 68/175 (38%), Gaps = 20/175 (11%)
Query: 280 GQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLGL-ELRGVRAGDSGRYTCRAEN 338
G + C A P ++W +V P ++ G+ + V D+G+Y C A N
Sbjct: 3503 GHAVEFECLALGDPKPQVTW---SKVGGHLRPGIVQSGGVVRIAHVELADAGQYRCTATN 3559
Query: 339 RLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPP 398
G+ Q + L VQ P+ + + Q R V G + C+ P
Sbjct: 3560 AAGTTQSHVLLLVQALPQ---ISMPQEVR-------------VPAGSAAVFPCIASGYPT 3603
Query: 399 ARLSWTRWGQTVGPSQPSDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSV 453
+SW++ ++ P + +L LP ++ + G + C A + G L V
Sbjct: 3604 PDISWSKLDGSLPPDSRLENNMLMLPSVRPQDAGTYVCTATNRQGKVKAFAHLQV 3658
Score = 31.6 bits (70), Expect = 2.6
Identities = 22/72 (30%), Positives = 31/72 (43%), Gaps = 6/72 (8%)
Query: 275 LEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLG-----LELRGVRAGDS 329
++ +GQ + C A P ++W L + S HP T L +R V+ D
Sbjct: 416 IQASRGQTVTFTCVAIGVPTPIINWRLNWGHIPS-HPRVTVTSEGGRGTLIIRDVKESDQ 474
Query: 330 GRYTCRAENRLG 341
G YTC A N G
Sbjct: 475 GAYTCEAMNARG 486
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.133 0.413
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 32,212,954
Number of Sequences: 37866
Number of extensions: 1700469
Number of successful extensions: 8191
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 148
Number of HSP's successfully gapped in prelim test: 251
Number of HSP's that attempted gapping in prelim test: 5093
Number of HSP's gapped (non-prelim): 1840
length of query: 698
length of database: 18,247,518
effective HSP length: 109
effective length of query: 589
effective length of database: 14,120,124
effective search space: 8316753036
effective search space used: 8316753036
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.