BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|205830405 solute carrier family 39 (zinc transporter), member 8 isoform b [Homo sapiens] (444 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|205830405 solute carrier family 39 (zinc transporter), member... 894 0.0 gi|24586665 solute carrier family 39 (zinc transporter), member ... 851 0.0 gi|205830403 solute carrier family 39 (zinc transporter), member... 851 0.0 gi|205830407 solute carrier family 39 (zinc transporter), member... 715 0.0 gi|190358541 solute carrier family 39 (zinc transporter), member... 394 e-109 gi|205830424 solute carrier family 39 (zinc transporter), member... 389 e-108 gi|190360568 solute carrier family 39 (zinc transporter), member... 389 e-108 gi|205830426 solute carrier family 39 (zinc transporter), member... 374 e-104 gi|115430259 solute carrier family 39 (zinc transporter), member... 170 2e-42 gi|115430255 solute carrier family 39 (zinc transporter), member... 170 2e-42 gi|223633939 solute carrier family 39 (zinc transporter), member... 165 7e-41 gi|223633937 solute carrier family 39 (zinc transporter), member... 157 2e-38 gi|153252201 solute carrier family 39 (zinc transporter), member... 139 7e-33 gi|206597541 solute carrier family 39 (metal ion transporter), m... 139 7e-33 gi|206597539 solute carrier family 39 (metal ion transporter), m... 139 7e-33 gi|187936949 solute carrier family 39 (zinc transporter), member... 136 3e-32 gi|55741750 solute carrier family 39 (zinc transporter), member ... 136 3e-32 gi|153252214 solute carrier family 39 (zinc transporter), member... 132 8e-31 gi|117553619 solute carrier family 39, member 7 [Homo sapiens] 84 2e-16 gi|117553608 solute carrier family 39, member 7 [Homo sapiens] 84 2e-16 gi|40255101 solute carrier family 39 (zinc transporter), member ... 74 3e-13 gi|190014617 solute carrier family 39 (zinc transporter), member... 72 1e-12 gi|229577422 solute carrier family 39, member 11 isoform 1 [Homo... 46 6e-05 gi|229577418 solute carrier family 39, member 11 isoform 2 [Homo... 46 6e-05 gi|156415986 solute carrier family 39 (zinc transporter), member... 45 2e-04 gi|21361423 solute carrier family 39 (zinc transporter), member ... 35 0.10 gi|40254928 solute carrier family 39 (zinc transporter), member ... 33 0.40 gi|169160919 PREDICTED: hypothetical protein [Homo sapiens] 31 2.6 gi|169162159 PREDICTED: hypothetical protein [Homo sapiens] 31 2.6 gi|169161152 PREDICTED: hypothetical protein [Homo sapiens] 31 2.6 >gi|205830405 solute carrier family 39 (zinc transporter), member 8 isoform b [Homo sapiens] Length = 444 Score = 894 bits (2311), Expect = 0.0 Identities = 444/444 (100%), Positives = 444/444 (100%) Query: 1 MAPGRAVAGLLLLAAAGLGGVAEGPGLAFSEDVLSVFGANLSLSAAQLQHLLEQMGAASR 60 MAPGRAVAGLLLLAAAGLGGVAEGPGLAFSEDVLSVFGANLSLSAAQLQHLLEQMGAASR Sbjct: 1 MAPGRAVAGLLLLAAAGLGGVAEGPGLAFSEDVLSVFGANLSLSAAQLQHLLEQMGAASR 60 Query: 61 VGVPEPGQLHFNQCLTAEEIFSLHGFSNATQITSSKFSVICPAVLQQLNFHPCEDRPKHK 120 VGVPEPGQLHFNQCLTAEEIFSLHGFSNATQITSSKFSVICPAVLQQLNFHPCEDRPKHK Sbjct: 61 VGVPEPGQLHFNQCLTAEEIFSLHGFSNATQITSSKFSVICPAVLQQLNFHPCEDRPKHK 120 Query: 121 TRPSHSEVWGYGFLSVTIINLASLLGLILTPLIKKSYFPKILTFFVGLAIGTLFSNAIFQ 180 TRPSHSEVWGYGFLSVTIINLASLLGLILTPLIKKSYFPKILTFFVGLAIGTLFSNAIFQ Sbjct: 121 TRPSHSEVWGYGFLSVTIINLASLLGLILTPLIKKSYFPKILTFFVGLAIGTLFSNAIFQ 180 Query: 181 LIPEAFGFDPKVDSYVEKAVAVFGGFYLLFFFERMLKMLLKTYGQNGHTHFGNDNFGPQE 240 LIPEAFGFDPKVDSYVEKAVAVFGGFYLLFFFERMLKMLLKTYGQNGHTHFGNDNFGPQE Sbjct: 181 LIPEAFGFDPKVDSYVEKAVAVFGGFYLLFFFERMLKMLLKTYGQNGHTHFGNDNFGPQE 240 Query: 241 KTHQPKALPAINGVTCYANPAVTEANGHIHFDNVSVVSLQDGKKEPSSCTCLKGPKLSEI 300 KTHQPKALPAINGVTCYANPAVTEANGHIHFDNVSVVSLQDGKKEPSSCTCLKGPKLSEI Sbjct: 241 KTHQPKALPAINGVTCYANPAVTEANGHIHFDNVSVVSLQDGKKEPSSCTCLKGPKLSEI 300 Query: 301 GTIAWMITLCDALHNFIDGLAIGASCTLSLLQGLSTSIAILCEEFPHELGDFVILLNAGM 360 GTIAWMITLCDALHNFIDGLAIGASCTLSLLQGLSTSIAILCEEFPHELGDFVILLNAGM Sbjct: 301 GTIAWMITLCDALHNFIDGLAIGASCTLSLLQGLSTSIAILCEEFPHELGDFVILLNAGM 360 Query: 361 STRQALLFNFLSACSCYVGLAFGILVGNNFAPNIIFALAGGMFLYISLADMFPEMNDMLR 420 STRQALLFNFLSACSCYVGLAFGILVGNNFAPNIIFALAGGMFLYISLADMFPEMNDMLR Sbjct: 361 STRQALLFNFLSACSCYVGLAFGILVGNNFAPNIIFALAGGMFLYISLADMFPEMNDMLR 420 Query: 421 EKIIKWATDDIKSQLHLLWIYTAR 444 EKIIKWATDDIKSQLHLLWIYTAR Sbjct: 421 EKIIKWATDDIKSQLHLLWIYTAR 444 >gi|24586665 solute carrier family 39 (zinc transporter), member 8 isoform a [Homo sapiens] Length = 460 Score = 851 bits (2199), Expect = 0.0 Identities = 424/429 (98%), Positives = 425/429 (99%) Query: 1 MAPGRAVAGLLLLAAAGLGGVAEGPGLAFSEDVLSVFGANLSLSAAQLQHLLEQMGAASR 60 MAPGRAVAGLLLLAAAGLGGVAEGPGLAFSEDVLSVFGANLSLSAAQLQHLLEQMGAASR Sbjct: 1 MAPGRAVAGLLLLAAAGLGGVAEGPGLAFSEDVLSVFGANLSLSAAQLQHLLEQMGAASR 60 Query: 61 VGVPEPGQLHFNQCLTAEEIFSLHGFSNATQITSSKFSVICPAVLQQLNFHPCEDRPKHK 120 VGVPEPGQLHFNQCLTAEEIFSLHGFSNATQITSSKFSVICPAVLQQLNFHPCEDRPKHK Sbjct: 61 VGVPEPGQLHFNQCLTAEEIFSLHGFSNATQITSSKFSVICPAVLQQLNFHPCEDRPKHK 120 Query: 121 TRPSHSEVWGYGFLSVTIINLASLLGLILTPLIKKSYFPKILTFFVGLAIGTLFSNAIFQ 180 TRPSHSEVWGYGFLSVTIINLASLLGLILTPLIKKSYFPKILTFFVGLAIGTLFSNAIFQ Sbjct: 121 TRPSHSEVWGYGFLSVTIINLASLLGLILTPLIKKSYFPKILTFFVGLAIGTLFSNAIFQ 180 Query: 181 LIPEAFGFDPKVDSYVEKAVAVFGGFYLLFFFERMLKMLLKTYGQNGHTHFGNDNFGPQE 240 LIPEAFGFDPKVDSYVEKAVAVFGGFYLLFFFERMLKMLLKTYGQNGHTHFGNDNFGPQE Sbjct: 181 LIPEAFGFDPKVDSYVEKAVAVFGGFYLLFFFERMLKMLLKTYGQNGHTHFGNDNFGPQE 240 Query: 241 KTHQPKALPAINGVTCYANPAVTEANGHIHFDNVSVVSLQDGKKEPSSCTCLKGPKLSEI 300 KTHQPKALPAINGVTCYANPAVTEANGHIHFDNVSVVSLQDGKKEPSSCTCLKGPKLSEI Sbjct: 241 KTHQPKALPAINGVTCYANPAVTEANGHIHFDNVSVVSLQDGKKEPSSCTCLKGPKLSEI 300 Query: 301 GTIAWMITLCDALHNFIDGLAIGASCTLSLLQGLSTSIAILCEEFPHELGDFVILLNAGM 360 GTIAWMITLCDALHNFIDGLAIGASCTLSLLQGLSTSIAILCEEFPHELGDFVILLNAGM Sbjct: 301 GTIAWMITLCDALHNFIDGLAIGASCTLSLLQGLSTSIAILCEEFPHELGDFVILLNAGM 360 Query: 361 STRQALLFNFLSACSCYVGLAFGILVGNNFAPNIIFALAGGMFLYISLADMFPEMNDMLR 420 STRQALLFNFLSACSCYVGLAFGILVGNNFAPNIIFALAGGMFLYISLADMFPEMNDMLR Sbjct: 361 STRQALLFNFLSACSCYVGLAFGILVGNNFAPNIIFALAGGMFLYISLADMFPEMNDMLR 420 Query: 421 EKIIKWATD 429 EK+ TD Sbjct: 421 EKVTGRKTD 429 >gi|205830403 solute carrier family 39 (zinc transporter), member 8 isoform a [Homo sapiens] Length = 460 Score = 851 bits (2199), Expect = 0.0 Identities = 424/429 (98%), Positives = 425/429 (99%) Query: 1 MAPGRAVAGLLLLAAAGLGGVAEGPGLAFSEDVLSVFGANLSLSAAQLQHLLEQMGAASR 60 MAPGRAVAGLLLLAAAGLGGVAEGPGLAFSEDVLSVFGANLSLSAAQLQHLLEQMGAASR Sbjct: 1 MAPGRAVAGLLLLAAAGLGGVAEGPGLAFSEDVLSVFGANLSLSAAQLQHLLEQMGAASR 60 Query: 61 VGVPEPGQLHFNQCLTAEEIFSLHGFSNATQITSSKFSVICPAVLQQLNFHPCEDRPKHK 120 VGVPEPGQLHFNQCLTAEEIFSLHGFSNATQITSSKFSVICPAVLQQLNFHPCEDRPKHK Sbjct: 61 VGVPEPGQLHFNQCLTAEEIFSLHGFSNATQITSSKFSVICPAVLQQLNFHPCEDRPKHK 120 Query: 121 TRPSHSEVWGYGFLSVTIINLASLLGLILTPLIKKSYFPKILTFFVGLAIGTLFSNAIFQ 180 TRPSHSEVWGYGFLSVTIINLASLLGLILTPLIKKSYFPKILTFFVGLAIGTLFSNAIFQ Sbjct: 121 TRPSHSEVWGYGFLSVTIINLASLLGLILTPLIKKSYFPKILTFFVGLAIGTLFSNAIFQ 180 Query: 181 LIPEAFGFDPKVDSYVEKAVAVFGGFYLLFFFERMLKMLLKTYGQNGHTHFGNDNFGPQE 240 LIPEAFGFDPKVDSYVEKAVAVFGGFYLLFFFERMLKMLLKTYGQNGHTHFGNDNFGPQE Sbjct: 181 LIPEAFGFDPKVDSYVEKAVAVFGGFYLLFFFERMLKMLLKTYGQNGHTHFGNDNFGPQE 240 Query: 241 KTHQPKALPAINGVTCYANPAVTEANGHIHFDNVSVVSLQDGKKEPSSCTCLKGPKLSEI 300 KTHQPKALPAINGVTCYANPAVTEANGHIHFDNVSVVSLQDGKKEPSSCTCLKGPKLSEI Sbjct: 241 KTHQPKALPAINGVTCYANPAVTEANGHIHFDNVSVVSLQDGKKEPSSCTCLKGPKLSEI 300 Query: 301 GTIAWMITLCDALHNFIDGLAIGASCTLSLLQGLSTSIAILCEEFPHELGDFVILLNAGM 360 GTIAWMITLCDALHNFIDGLAIGASCTLSLLQGLSTSIAILCEEFPHELGDFVILLNAGM Sbjct: 301 GTIAWMITLCDALHNFIDGLAIGASCTLSLLQGLSTSIAILCEEFPHELGDFVILLNAGM 360 Query: 361 STRQALLFNFLSACSCYVGLAFGILVGNNFAPNIIFALAGGMFLYISLADMFPEMNDMLR 420 STRQALLFNFLSACSCYVGLAFGILVGNNFAPNIIFALAGGMFLYISLADMFPEMNDMLR Sbjct: 361 STRQALLFNFLSACSCYVGLAFGILVGNNFAPNIIFALAGGMFLYISLADMFPEMNDMLR 420 Query: 421 EKIIKWATD 429 EK+ TD Sbjct: 421 EKVTGRKTD 429 >gi|205830407 solute carrier family 39 (zinc transporter), member 8 isoform c [Homo sapiens] Length = 393 Score = 715 bits (1845), Expect = 0.0 Identities = 352/357 (98%), Positives = 353/357 (98%) Query: 73 QCLTAEEIFSLHGFSNATQITSSKFSVICPAVLQQLNFHPCEDRPKHKTRPSHSEVWGYG 132 QCLTAEEIFSLHGFSNATQITSSKFSVICPAVLQQLNFHPCEDRPKHKTRPSHSEVWGYG Sbjct: 6 QCLTAEEIFSLHGFSNATQITSSKFSVICPAVLQQLNFHPCEDRPKHKTRPSHSEVWGYG 65 Query: 133 FLSVTIINLASLLGLILTPLIKKSYFPKILTFFVGLAIGTLFSNAIFQLIPEAFGFDPKV 192 FLSVTIINLASLLGLILTPLIKKSYFPKILTFFVGLAIGTLFSNAIFQLIPEAFGFDPKV Sbjct: 66 FLSVTIINLASLLGLILTPLIKKSYFPKILTFFVGLAIGTLFSNAIFQLIPEAFGFDPKV 125 Query: 193 DSYVEKAVAVFGGFYLLFFFERMLKMLLKTYGQNGHTHFGNDNFGPQEKTHQPKALPAIN 252 DSYVEKAVAVFGGFYLLFFFERMLKMLLKTYGQNGHTHFGNDNFGPQEKTHQPKALPAIN Sbjct: 126 DSYVEKAVAVFGGFYLLFFFERMLKMLLKTYGQNGHTHFGNDNFGPQEKTHQPKALPAIN 185 Query: 253 GVTCYANPAVTEANGHIHFDNVSVVSLQDGKKEPSSCTCLKGPKLSEIGTIAWMITLCDA 312 GVTCYANPAVTEANGHIHFDNVSVVSLQDGKKEPSSCTCLKGPKLSEIGTIAWMITLCDA Sbjct: 186 GVTCYANPAVTEANGHIHFDNVSVVSLQDGKKEPSSCTCLKGPKLSEIGTIAWMITLCDA 245 Query: 313 LHNFIDGLAIGASCTLSLLQGLSTSIAILCEEFPHELGDFVILLNAGMSTRQALLFNFLS 372 LHNFIDGLAIGASCTLSLLQGLSTSIAILCEEFPHELGDFVILLNAGMSTRQALLFNFLS Sbjct: 246 LHNFIDGLAIGASCTLSLLQGLSTSIAILCEEFPHELGDFVILLNAGMSTRQALLFNFLS 305 Query: 373 ACSCYVGLAFGILVGNNFAPNIIFALAGGMFLYISLADMFPEMNDMLREKIIKWATD 429 ACSCYVGLAFGILVGNNFAPNIIFALAGGMFLYISLADMFPEMNDMLREK+ TD Sbjct: 306 ACSCYVGLAFGILVGNNFAPNIIFALAGGMFLYISLADMFPEMNDMLREKVTGRKTD 362 >gi|190358541 solute carrier family 39 (zinc transporter), member 14 isoform b [Homo sapiens] Length = 492 Score = 394 bits (1011), Expect = e-109 Identities = 216/427 (50%), Positives = 292/427 (68%), Gaps = 22/427 (5%) Query: 15 AAGLGGVAEGPGLAFSEDVLSVFGANLSLSAAQLQHLLEQMGAA-SRVGVPEPGQLHFN- 72 A+ LG A +F +D++ +G SL+ QL+ LL + R V + Q H N Sbjct: 30 ASSLGAPAISAA-SFLQDLIHRYGEGDSLTLQQLKALLNHLDVGVGRGNVTQHVQGHRNL 88 Query: 73 -QCLTAEEIFSLHGFSNATQITSSKFSVICPAVLQQLNFHPC--------EDRPKHKTRP 123 C ++ ++F+ H FS ++I SS+ CP +LQQL+ C E+ + RP Sbjct: 89 STCFSSGDLFTAHNFSEQSRIGSSELQEFCPTILQQLDSRACTSENQENEENEQTEEGRP 148 Query: 124 SHSEVWGYGFLSVTIINLASLLGLILTPLIKKSYFPKILTFFVGLAIGTLFSNAIFQLIP 183 S EVWG+GFLSV++INLASLLG+++ P +K++F ++LT+F+ L+IGTL SNA+FQLIP Sbjct: 149 SAVEVWGFGFLSVSLINLASLLGVLVLPCTEKAFFSRVLTYFIALSIGTLLSNALFQLIP 208 Query: 184 EAFGFDPKVDSYVEKAVAVFGGFYLLFFFERMLKMLLKTYGQN--GHTHFGNDNFGPQEK 241 EAFGF+P D YV K+ VFGGFYL FF E++LK+LLK ++ GH+H+ +++ P +K Sbjct: 209 EAFGFNPLEDYYVSKSAVVFGGFYLFFFTEKILKILLKQKNEHHHGHSHYASESL-PSKK 267 Query: 242 THQPKALPAI-NGVTCYANP--AVTEANGHIHFDNVSVV----SLQDGKKEPSSCTCLKG 294 + + + NG + P +E +G + V+ S+QD + S+C LKG Sbjct: 268 DQEEGVMEKLQNGDLDHMIPQHCSSELDGKAPMVDEKVIVGSLSVQDLQASQSACYWLKG 327 Query: 295 PKLSEIGTIAWMITLCDALHNFIDGLAIGASCTLSLLQGLSTSIAILCEEFPHELGDFVI 354 + S+IGT+AWMITL D LHNFIDGLAIGAS T+S+ QG+STS+AILCEEFPHELGDFVI Sbjct: 328 VRYSDIGTLAWMITLSDGLHNFIDGLAIGASFTVSVFQGISTSVAILCEEFPHELGDFVI 387 Query: 355 LLNAGMSTRQALLFNFLSACSCYVGLAFGILVGNNFAPNIIFALAGGMFLYISLADMFPE 414 LLNAGMS +QAL FNFLSAC CY+GLAFGIL G++F+ N IFALAGGMFLYISLADMFPE Sbjct: 388 LLNAGMSIQQALFFNFLSACCCYLGLAFGILAGSHFSANWIFALAGGMFLYISLADMFPE 447 Query: 415 MNDMLRE 421 MN++ +E Sbjct: 448 MNEVCQE 454 >gi|205830424 solute carrier family 39 (zinc transporter), member 14 isoform a [Homo sapiens] Length = 492 Score = 389 bits (998), Expect = e-108 Identities = 214/427 (50%), Positives = 288/427 (67%), Gaps = 22/427 (5%) Query: 15 AAGLGGVAEGPGLAFSEDVLSVFGANLSLSAAQLQHLLEQMGAA-SRVGVPEPGQLHFN- 72 A+ LG A +F +D++ +G SL+ QL+ LL + R V + Q H N Sbjct: 30 ASSLGAPAISAA-SFLQDLIHRYGEGDSLTLQQLKALLNHLDVGVGRGNVTQHVQGHRNL 88 Query: 73 -QCLTAEEIFSLHGFSNATQITSSKFSVICPAVLQQLNFHPC--------EDRPKHKTRP 123 C ++ ++F+ H FS ++I SS+ CP +LQQL+ C E+ + RP Sbjct: 89 STCFSSGDLFTAHNFSEQSRIGSSELQEFCPTILQQLDSRACTSENQENEENEQTEEGRP 148 Query: 124 SHSEVWGYGFLSVTIINLASLLGLILTPLIKKSYFPKILTFFVGLAIGTLFSNAIFQLIP 183 S EVWGYG L VT+I+L SLLG + P +KK+++ ++L +F+ LAIGTL+SNA+FQLIP Sbjct: 149 SAVEVWGYGLLCVTVISLCSLLGASVVPFMKKTFYKRLLLYFIALAIGTLYSNALFQLIP 208 Query: 184 EAFGFDPKVDSYVEKAVAVFGGFYLLFFFERMLKMLLKTYGQN--GHTHFGNDNFGPQEK 241 EAFGF+P D YV K+ VFGGFYL FF E++LK+LLK ++ GH+H+ +++ P +K Sbjct: 209 EAFGFNPLEDYYVSKSAVVFGGFYLFFFTEKILKILLKQKNEHHHGHSHYASESL-PSKK 267 Query: 242 THQPKALPAI-NGVTCYANP--AVTEANGHIHFDNVSVV----SLQDGKKEPSSCTCLKG 294 + + + NG + P +E +G + V+ S+QD + S+C LKG Sbjct: 268 DQEEGVMEKLQNGDLDHMIPQHCSSELDGKAPMVDEKVIVGSLSVQDLQASQSACYWLKG 327 Query: 295 PKLSEIGTIAWMITLCDALHNFIDGLAIGASCTLSLLQGLSTSIAILCEEFPHELGDFVI 354 + S+IGT+AWMITL D LHNFIDGLAIGAS T+S+ QG+STS+AILCEEFPHELGDFVI Sbjct: 328 VRYSDIGTLAWMITLSDGLHNFIDGLAIGASFTVSVFQGISTSVAILCEEFPHELGDFVI 387 Query: 355 LLNAGMSTRQALLFNFLSACSCYVGLAFGILVGNNFAPNIIFALAGGMFLYISLADMFPE 414 LLNAGMS +QAL FNFLSAC CY+GLAFGIL G++F+ N IFALAGGMFLYISLADMFPE Sbjct: 388 LLNAGMSIQQALFFNFLSACCCYLGLAFGILAGSHFSANWIFALAGGMFLYISLADMFPE 447 Query: 415 MNDMLRE 421 MN++ +E Sbjct: 448 MNEVCQE 454 >gi|190360568 solute carrier family 39 (zinc transporter), member 14 isoform a [Homo sapiens] Length = 492 Score = 389 bits (998), Expect = e-108 Identities = 214/427 (50%), Positives = 288/427 (67%), Gaps = 22/427 (5%) Query: 15 AAGLGGVAEGPGLAFSEDVLSVFGANLSLSAAQLQHLLEQMGAA-SRVGVPEPGQLHFN- 72 A+ LG A +F +D++ +G SL+ QL+ LL + R V + Q H N Sbjct: 30 ASSLGAPAISAA-SFLQDLIHRYGEGDSLTLQQLKALLNHLDVGVGRGNVTQHVQGHRNL 88 Query: 73 -QCLTAEEIFSLHGFSNATQITSSKFSVICPAVLQQLNFHPC--------EDRPKHKTRP 123 C ++ ++F+ H FS ++I SS+ CP +LQQL+ C E+ + RP Sbjct: 89 STCFSSGDLFTAHNFSEQSRIGSSELQEFCPTILQQLDSRACTSENQENEENEQTEEGRP 148 Query: 124 SHSEVWGYGFLSVTIINLASLLGLILTPLIKKSYFPKILTFFVGLAIGTLFSNAIFQLIP 183 S EVWGYG L VT+I+L SLLG + P +KK+++ ++L +F+ LAIGTL+SNA+FQLIP Sbjct: 149 SAVEVWGYGLLCVTVISLCSLLGASVVPFMKKTFYKRLLLYFIALAIGTLYSNALFQLIP 208 Query: 184 EAFGFDPKVDSYVEKAVAVFGGFYLLFFFERMLKMLLKTYGQN--GHTHFGNDNFGPQEK 241 EAFGF+P D YV K+ VFGGFYL FF E++LK+LLK ++ GH+H+ +++ P +K Sbjct: 209 EAFGFNPLEDYYVSKSAVVFGGFYLFFFTEKILKILLKQKNEHHHGHSHYASESL-PSKK 267 Query: 242 THQPKALPAI-NGVTCYANP--AVTEANGHIHFDNVSVV----SLQDGKKEPSSCTCLKG 294 + + + NG + P +E +G + V+ S+QD + S+C LKG Sbjct: 268 DQEEGVMEKLQNGDLDHMIPQHCSSELDGKAPMVDEKVIVGSLSVQDLQASQSACYWLKG 327 Query: 295 PKLSEIGTIAWMITLCDALHNFIDGLAIGASCTLSLLQGLSTSIAILCEEFPHELGDFVI 354 + S+IGT+AWMITL D LHNFIDGLAIGAS T+S+ QG+STS+AILCEEFPHELGDFVI Sbjct: 328 VRYSDIGTLAWMITLSDGLHNFIDGLAIGASFTVSVFQGISTSVAILCEEFPHELGDFVI 387 Query: 355 LLNAGMSTRQALLFNFLSACSCYVGLAFGILVGNNFAPNIIFALAGGMFLYISLADMFPE 414 LLNAGMS +QAL FNFLSAC CY+GLAFGIL G++F+ N IFALAGGMFLYISLADMFPE Sbjct: 388 LLNAGMSIQQALFFNFLSACCCYLGLAFGILAGSHFSANWIFALAGGMFLYISLADMFPE 447 Query: 415 MNDMLRE 421 MN++ +E Sbjct: 448 MNEVCQE 454 >gi|205830426 solute carrier family 39 (zinc transporter), member 14 isoform c [Homo sapiens] Length = 481 Score = 374 bits (961), Expect = e-104 Identities = 208/417 (49%), Positives = 279/417 (66%), Gaps = 22/417 (5%) Query: 15 AAGLGGVAEGPGLAFSEDVLSVFGANLSLSAAQLQHLLEQMGAA-SRVGVPEPGQLHFN- 72 A+ LG A +F +D++ +G SL+ QL+ LL + R V + Q H N Sbjct: 30 ASSLGAPAISAA-SFLQDLIHRYGEGDSLTLQQLKALLNHLDVGVGRGNVTQHVQGHRNL 88 Query: 73 -QCLTAEEIFSLHGFSNATQITSSKFSVICPAVLQQLNFHPC--------EDRPKHKTRP 123 C ++ ++F+ H FS ++I SS+ CP +LQQL+ C E+ + RP Sbjct: 89 STCFSSGDLFTAHNFSEQSRIGSSELQEFCPTILQQLDSRACTSENQENEENEQTEEGRP 148 Query: 124 SHSEVWGYGFLSVTIINLASLLGLILTPLIKKSYFPKILTFFVGLAIGTLFSNAIFQLIP 183 S EVWGYG L VT+I+L SLLG + P +KK+++ ++L +F+ LAIGTL+SNA+FQLIP Sbjct: 149 SAVEVWGYGLLCVTVISLCSLLGASVVPFMKKTFYKRLLLYFIALAIGTLYSNALFQLIP 208 Query: 184 EAFGFDPKVDSYVEKAVAVFGGFYLLFFFERMLKMLLKTYGQN--GHTHFGNDNFGPQEK 241 EAFGF+P D YV K+ VFGGFYL FF E++LK+LLK ++ GH+H+ +++ P +K Sbjct: 209 EAFGFNPLEDYYVSKSAVVFGGFYLFFFTEKILKILLKQKNEHHHGHSHYASESL-PSKK 267 Query: 242 THQPKALPAI-NGVTCYANP--AVTEANGHIHFDNVSVV----SLQDGKKEPSSCTCLKG 294 + + + NG + P +E +G + V+ S+QD + S+C LKG Sbjct: 268 DQEEGVMEKLQNGDLDHMIPQHCSSELDGKAPMVDEKVIVGSLSVQDLQASQSACYWLKG 327 Query: 295 PKLSEIGTIAWMITLCDALHNFIDGLAIGASCTLSLLQGLSTSIAILCEEFPHELGDFVI 354 + S+IGT+AWMITL D LHNFIDGLAIGAS T+S+ QG+STS+AILCEEFPHELGDFVI Sbjct: 328 VRYSDIGTLAWMITLSDGLHNFIDGLAIGASFTVSVFQGISTSVAILCEEFPHELGDFVI 387 Query: 355 LLNAGMSTRQALLFNFLSACSCYVGLAFGILVGNNFAPNIIFALAGGMFLYISLADM 411 LLNAGMS +QAL FNFLSAC CY+GLAFGIL G++F+ N IFALAGGMFLYISLADM Sbjct: 388 LLNAGMSIQQALFFNFLSACCCYLGLAFGILAGSHFSANWIFALAGGMFLYISLADM 444 >gi|115430259 solute carrier family 39 (zinc transporter), member 4 isoform 1 [Homo sapiens] Length = 622 Score = 170 bits (431), Expect = 2e-42 Identities = 127/398 (31%), Positives = 188/398 (47%), Gaps = 53/398 (13%) Query: 46 AQLQHLLEQMGAASRVGVP-----EPGQLHFNQCLTAEEIFSLHGFSNATQITSSKFSVI 100 A H GA+SR VP + CL+A ++ + +G S +T ++ + Sbjct: 212 AHSDHSHRHRGASSRDPVPLISSSNSSSVWDTVCLSARDVMAAYGLSEQAGVTPEAWAQL 271 Query: 101 CPAVLQQLNFHPC--EDRPKHKTRPSHSEVWGYGFLSVTIINLASLLGLILTPLIK-KSY 157 PA+LQQ C + RP + + S SE + YG L+ +I L ++ GL+L + Sbjct: 272 SPALLQQQLSGACTSQSRPPVQDQLSQSERYLYGSLATLLICLCAVFGLLLLTCTGCRGV 331 Query: 158 FPKILTFFVGLAIGTLFSNAIFQLIPEAFGFDPKVDSYVE-----KAVAVFGGFYLLFFF 212 IL F+ LA+G L +A+ L P+ G + + + +A+ G Y F F Sbjct: 332 THYILQTFLSLAVGALTGDAVLHLTPKVLGLHTHSEEGLSPQPTWRLLAMLAGLYAFFLF 391 Query: 213 ERMLKMLL--------------KTYGQNGHTHFGNDNFGPQEKTHQPKALPAINGVTCYA 258 E + +LL ++ GH+H + P E QPK P G Sbjct: 392 ENLFNLLLPRDPEDLEDGPCGHSSHSHGGHSHGVSLQLAPSE-LRQPK--PPHEGSRA-- 446 Query: 259 NPAVTEANGHIHFDNVSVVSLQDGKKEPSSCTCLKGPKLSEIGTIAWMITLCDALHNFID 318 D V+ S + EP + E+ + +MITL DA+HNF D Sbjct: 447 -------------DLVAEESPELLNPEPRRLS-------PELRLLPYMITLGDAVHNFAD 486 Query: 319 GLAIGASCTLSLLQGLSTSIAILCEEFPHELGDFVILLNAGMSTRQALLFNFLSACSCYV 378 GLA+GA+ S GL+TS+A+ C E PHELGDF LL+AG+S RQALL N SA + + Sbjct: 487 GLAVGAAFASSWKTGLATSLAVFCHELPHELGDFAALLHAGLSVRQALLLNLASALTAFA 546 Query: 379 GLAFGILVG-NNFAPNIIFALAGGMFLYISLADMFPEM 415 GL + VG + + I A+A G+FLY++L DM P M Sbjct: 547 GLYVALAVGVSEESEAWILAVATGLFLYVALCDMLPAM 584 >gi|115430255 solute carrier family 39 (zinc transporter), member 4 isoform 2 [Homo sapiens] Length = 647 Score = 170 bits (431), Expect = 2e-42 Identities = 127/398 (31%), Positives = 188/398 (47%), Gaps = 53/398 (13%) Query: 46 AQLQHLLEQMGAASRVGVP-----EPGQLHFNQCLTAEEIFSLHGFSNATQITSSKFSVI 100 A H GA+SR VP + CL+A ++ + +G S +T ++ + Sbjct: 237 AHSDHSHRHRGASSRDPVPLISSSNSSSVWDTVCLSARDVMAAYGLSEQAGVTPEAWAQL 296 Query: 101 CPAVLQQLNFHPC--EDRPKHKTRPSHSEVWGYGFLSVTIINLASLLGLILTPLIK-KSY 157 PA+LQQ C + RP + + S SE + YG L+ +I L ++ GL+L + Sbjct: 297 SPALLQQQLSGACTSQSRPPVQDQLSQSERYLYGSLATLLICLCAVFGLLLLTCTGCRGV 356 Query: 158 FPKILTFFVGLAIGTLFSNAIFQLIPEAFGFDPKVDSYVE-----KAVAVFGGFYLLFFF 212 IL F+ LA+G L +A+ L P+ G + + + +A+ G Y F F Sbjct: 357 THYILQTFLSLAVGALTGDAVLHLTPKVLGLHTHSEEGLSPQPTWRLLAMLAGLYAFFLF 416 Query: 213 ERMLKMLL--------------KTYGQNGHTHFGNDNFGPQEKTHQPKALPAINGVTCYA 258 E + +LL ++ GH+H + P E QPK P G Sbjct: 417 ENLFNLLLPRDPEDLEDGPCGHSSHSHGGHSHGVSLQLAPSE-LRQPK--PPHEGSRA-- 471 Query: 259 NPAVTEANGHIHFDNVSVVSLQDGKKEPSSCTCLKGPKLSEIGTIAWMITLCDALHNFID 318 D V+ S + EP + E+ + +MITL DA+HNF D Sbjct: 472 -------------DLVAEESPELLNPEPRRLS-------PELRLLPYMITLGDAVHNFAD 511 Query: 319 GLAIGASCTLSLLQGLSTSIAILCEEFPHELGDFVILLNAGMSTRQALLFNFLSACSCYV 378 GLA+GA+ S GL+TS+A+ C E PHELGDF LL+AG+S RQALL N SA + + Sbjct: 512 GLAVGAAFASSWKTGLATSLAVFCHELPHELGDFAALLHAGLSVRQALLLNLASALTAFA 571 Query: 379 GLAFGILVG-NNFAPNIIFALAGGMFLYISLADMFPEM 415 GL + VG + + I A+A G+FLY++L DM P M Sbjct: 572 GLYVALAVGVSEESEAWILAVATGLFLYVALCDMLPAM 609 >gi|223633939 solute carrier family 39 (zinc transporter), member 12 isoform 1 [Homo sapiens] Length = 691 Score = 165 bits (418), Expect = 7e-41 Identities = 122/393 (31%), Positives = 197/393 (50%), Gaps = 67/393 (17%) Query: 65 EPGQLHFNQ-CLTAEEIFSLHGFSNATQITSSKFSVICPAVLQQLNFHPCEDRPKH---K 120 E G + ++Q C +A ++ + + I+ F + P ++QQL C PK K Sbjct: 300 EDGPVSWDQTCFSARQLVEIFLQKGLSLISKEDFKQMSPGIIQQLLSCSCH-LPKDQQAK 358 Query: 121 TRPSHSEVWGYGFLSVTIINLASLLG--LILTPLIKKSYFPKILTFFVGLAIGTLFSNAI 178 P+ E +GY ++VT++ L S+LG L+L +++Y IL FVGLA+GTL +A+ Sbjct: 359 LPPTTLEKYGYSTVAVTLLTLGSMLGTALVLFHSCEENY-RLILQLFVGLAVGTLSGDAL 417 Query: 179 FQLIPEA----------FGFDPKVDSYVEKAVAVFGGFYLLFFFERMLKMLLKTYGQNGH 228 LIP+ FG + ++ K + + GG + F E+ +L+ Sbjct: 418 LHLIPQVLGLHKQEAPEFGHFHESKGHIWKLMGLIGGIHGFFLIEKCFILLV-------- 469 Query: 229 THFGNDNFGPQEKTHQPKALPAINGVTCYANPAVTEANGHIHFDNVSVVSLQDGKKEPSS 288 P +K + L +NG +++ H S +S Q G+ + +S Sbjct: 470 --------SPNDK----QGLSLVNGHVGHSH----------HLALNSELSDQAGRGKSAS 507 Query: 289 CTCLKGP------------------KLSEIGTIAWMITLCDALHNFIDGLAIGASCTLSL 330 LK P K I +A MI + D+LHNF DGLAIGA+ + S Sbjct: 508 TIQLKSPEDSQAAEMPIGSMTASNRKCKAISLLAIMILVGDSLHNFADGLAIGAAFSSSS 567 Query: 331 LQGLSTSIAILCEEFPHELGDFVILLNAGMSTRQALLFNFLSACSCYVGLAFGILV-GNN 389 G++T+IAILC E PHE+GDF +LL++G+S + A+L NF+S+ + ++GL G+ V + Sbjct: 568 ESGVTTTIAILCHEIPHEMGDFAVLLSSGLSMKTAILMNFISSLTAFMGLYIGLSVSADP 627 Query: 390 FAPNIIFALAGGMFLYISLADMFPEMNDMLREK 422 + IF + GMFLY+SL +M PEM + ++ Sbjct: 628 CVQDWIFTVTAGMFLYLSLVEMLPEMTHVQTQR 660 >gi|223633937 solute carrier family 39 (zinc transporter), member 12 isoform 2 [Homo sapiens] Length = 654 Score = 157 bits (397), Expect = 2e-38 Identities = 112/375 (29%), Positives = 180/375 (48%), Gaps = 68/375 (18%) Query: 65 EPGQLHFNQ-CLTAEEIFSLHGFSNATQITSSKFSVICPAVLQQLNFHPCEDRPKH---K 120 E G + ++Q C +A ++ + + I+ F + P ++QQL C PK K Sbjct: 300 EDGPVSWDQTCFSARQLVEIFLQKGLSLISKEDFKQMSPGIIQQLLSCSCH-LPKDQQAK 358 Query: 121 TRPSHSEVWGYGFLSVTIINLASLLG--LILTPLIKKSYFPKILTFFVGLAIGTLFSNAI 178 P+ E +GY ++VT++ L S+LG L+L +++Y IL FVGLA+GTL +A+ Sbjct: 359 LPPTTLEKYGYSTVAVTLLTLGSMLGTALVLFHSCEENY-RLILQLFVGLAVGTLSGDAL 417 Query: 179 FQLIPEA----------FGFDPKVDSYVEKAVAVFGGFYLLFFFERMLKMLLKTYGQNGH 228 LIP+ FG + ++ K + + GG + F E+ +L+ Sbjct: 418 LHLIPQVLGLHKQEAPEFGHFHESKGHIWKLMGLIGGIHGFFLIEKCFILLVSP------ 471 Query: 229 THFGNDNFGPQEKTHQPKALPAINGVTCYANPAVTEANGHIHFDNVSVVSLQDGKKEPSS 288 ND P++ + P Sbjct: 472 ----NDKKSPEDS---------------------------------------QAAEMPIG 488 Query: 289 CTCLKGPKLSEIGTIAWMITLCDALHNFIDGLAIGASCTLSLLQGLSTSIAILCEEFPHE 348 K I +A MI + D+LHNF DGLAIGA+ + S G++T+IAILC E PHE Sbjct: 489 SMTASNRKCKAISLLAIMILVGDSLHNFADGLAIGAAFSSSSESGVTTTIAILCHEIPHE 548 Query: 349 LGDFVILLNAGMSTRQALLFNFLSACSCYVGLAFGILV-GNNFAPNIIFALAGGMFLYIS 407 +GDF +LL++G+S + A+L NF+S+ + ++GL G+ V + + IF + GMFLY+S Sbjct: 549 MGDFAVLLSSGLSMKTAILMNFISSLTAFMGLYIGLSVSADPCVQDWIFTVTAGMFLYLS 608 Query: 408 LADMFPEMNDMLREK 422 L +M PEM + ++ Sbjct: 609 LVEMLPEMTHVQTQR 623 >gi|153252201 solute carrier family 39 (zinc transporter), member 6 isoform 1 [Homo sapiens] Length = 755 Score = 139 bits (349), Expect = 7e-33 Identities = 69/132 (52%), Positives = 92/132 (69%), Gaps = 6/132 (4%) Query: 300 IGTIAWMITLCDALHNFIDGLAIGASCTLSLLQGLSTSIAILCEEFPHELGDFVILLNAG 359 + T+AWM+ + D LHNF DGLAIGA+ T L GLSTS+A+ C E PHELGDF +LL AG Sbjct: 592 VATLAWMVIMGDGLHNFSDGLAIGAAFTEGLSSGLSTSVAVFCHELPHELGDFAVLLKAG 651 Query: 360 MSTRQALLFNFLSACSCYVGLAFGILVGNNFAPNI---IFALAGGMFLYISLADMFPEM- 415 M+ +QA+L+N LSA Y+G+A GI +G ++A N+ IFAL G+F+Y++L DM PEM Sbjct: 652 MTVKQAVLYNALSAMLAYLGMATGIFIG-HYAENVSMWIFALTAGLFMYVALVDMVPEML 710 Query: 416 -NDMLREKIIKW 426 ND +W Sbjct: 711 HNDASDHGCSRW 722 Score = 79.7 bits (195), Expect = 5e-15 Identities = 53/194 (27%), Positives = 95/194 (48%), Gaps = 15/194 (7%) Query: 25 PGLAFSEDVLSVFGANLSLSAAQLQHLLEQMGAASRVGVPEPGQLHFN-------QCLTA 77 PG F +DV S +++ S +++ L + S V P G ++ +C A Sbjct: 210 PGKLFPKDVSSSTPPSVT-SKSRVSRLAGRKTNES-VSEPRKGFMYSRNTNENPQECFNA 267 Query: 78 EEIFSLHGFSNATQITSSKFSVICPAVLQQLNFHPCEDRPKHKTRP------SHSEVWGY 131 ++ + HG + +++F+ +CPA++ Q++ C K S W Sbjct: 268 SKLLTSHGMGIQVPLNATEFNYLCPAIINQIDARSCLIHTSEKKAEIPPKTYSLQIAWVG 327 Query: 132 GFLSVTIINLASLLGLILTPLIKKSYFPKILTFFVGLAIGTLFSNAIFQLIPEAFGFDPK 191 GF++++II+ SLLG+IL PL+ + +F +L+F V LA+GTL +A L+P + Sbjct: 328 GFIAISIISFLSLLGVILVPLMNRVFFKFLLSFLVALAVGTLSGDAFLHLLPHSHASHHH 387 Query: 192 VDSYVEKAVAVFGG 205 S+ E A+ + G Sbjct: 388 SHSHEEPAMEMKRG 401 >gi|206597541 solute carrier family 39 (metal ion transporter), member 5 [Homo sapiens] Length = 540 Score = 139 bits (349), Expect = 7e-33 Identities = 110/370 (29%), Positives = 166/370 (44%), Gaps = 49/370 (13%) Query: 70 HFNQ-CLTAEEIFSLHGFSNATQITSSKFSVICPAVLQQLNFHPCEDRPKHKTRPSHSEV 128 H N+ CL ++ G S A +T +F+++CPA+L Q++ C P Sbjct: 153 HLNEDCLNGSQLLVNFGLSPAAPLTPRQFALLCPALLYQIDSRVCIGAPAPAPPGDLLSA 212 Query: 129 WGYGFLSVTIINLASLLGLILTPLIKKSYFPKILTFFVGLAIGTLFSNAIFQLIPEAF-- 186 L+V +++L S L L+L L+ +L F LA+GTL +A+ L+P A Sbjct: 213 LLQSALAVLLLSLPSPLSLLLLRLLGPRLLRPLLGFLGALAVGTLCGDALLHLLPHAQEG 272 Query: 187 -----GFDPKVDSYVEKAVAVFGGFYLLFFFERMLKMLLKTYGQNGHTHFGNDNFGPQEK 241 G P+ D + ++V GG +LLF E ML +L H + + Sbjct: 273 RHAGPGGLPEKD--LGPGLSVLGGLFLLFVLENMLGLLR-------HRGLRPRCCRRKRR 323 Query: 242 THQPKALPAINGVTCYANP--AVTEANGHIHFDNVSVVSLQDGKKEPSSCTCLKGPKLSE 299 + + L NG P A E G++E +S P L+ Sbjct: 324 NLETRNLDPENGSGMALQPLQAAPEPGAQ-------------GQREKNS---QHPPALAP 367 Query: 300 IG------------TIAWMITLCDALHNFIDGLAIGASCTLSLLQGLSTSIAILCEEFPH 347 G I WM+ L D LHN DGLAIGA+ + GLST++A+ C E PH Sbjct: 368 PGHQGHSHGHQGGTDITWMVLLGDGLHNLTDGLAIGAAFSDGFSSGLSTTLAVFCHELPH 427 Query: 348 ELGDFVILLNAGMSTRQALLFNFLSACSCYVGLAFGILVGNNFAPNI--IFALAGGMFLY 405 ELGDF +LL +G+S R+ LL + +S G G+ + P +F + G+FLY Sbjct: 428 ELGDFAMLLQSGLSFRRLLLLSLVSGALGLGGAVLGVGLSLGPVPLTPWVFGVTAGVFLY 487 Query: 406 ISLADMFPEM 415 ++L DM P + Sbjct: 488 VALVDMLPAL 497 >gi|206597539 solute carrier family 39 (metal ion transporter), member 5 [Homo sapiens] Length = 540 Score = 139 bits (349), Expect = 7e-33 Identities = 110/370 (29%), Positives = 166/370 (44%), Gaps = 49/370 (13%) Query: 70 HFNQ-CLTAEEIFSLHGFSNATQITSSKFSVICPAVLQQLNFHPCEDRPKHKTRPSHSEV 128 H N+ CL ++ G S A +T +F+++CPA+L Q++ C P Sbjct: 153 HLNEDCLNGSQLLVNFGLSPAAPLTPRQFALLCPALLYQIDSRVCIGAPAPAPPGDLLSA 212 Query: 129 WGYGFLSVTIINLASLLGLILTPLIKKSYFPKILTFFVGLAIGTLFSNAIFQLIPEAF-- 186 L+V +++L S L L+L L+ +L F LA+GTL +A+ L+P A Sbjct: 213 LLQSALAVLLLSLPSPLSLLLLRLLGPRLLRPLLGFLGALAVGTLCGDALLHLLPHAQEG 272 Query: 187 -----GFDPKVDSYVEKAVAVFGGFYLLFFFERMLKMLLKTYGQNGHTHFGNDNFGPQEK 241 G P+ D + ++V GG +LLF E ML +L H + + Sbjct: 273 RHAGPGGLPEKD--LGPGLSVLGGLFLLFVLENMLGLLR-------HRGLRPRCCRRKRR 323 Query: 242 THQPKALPAINGVTCYANP--AVTEANGHIHFDNVSVVSLQDGKKEPSSCTCLKGPKLSE 299 + + L NG P A E G++E +S P L+ Sbjct: 324 NLETRNLDPENGSGMALQPLQAAPEPGAQ-------------GQREKNS---QHPPALAP 367 Query: 300 IG------------TIAWMITLCDALHNFIDGLAIGASCTLSLLQGLSTSIAILCEEFPH 347 G I WM+ L D LHN DGLAIGA+ + GLST++A+ C E PH Sbjct: 368 PGHQGHSHGHQGGTDITWMVLLGDGLHNLTDGLAIGAAFSDGFSSGLSTTLAVFCHELPH 427 Query: 348 ELGDFVILLNAGMSTRQALLFNFLSACSCYVGLAFGILVGNNFAPNI--IFALAGGMFLY 405 ELGDF +LL +G+S R+ LL + +S G G+ + P +F + G+FLY Sbjct: 428 ELGDFAMLLQSGLSFRRLLLLSLVSGALGLGGAVLGVGLSLGPVPLTPWVFGVTAGVFLY 487 Query: 406 ISLADMFPEM 415 ++L DM P + Sbjct: 488 VALVDMLPAL 497 >gi|187936949 solute carrier family 39 (zinc transporter), member 10 [Homo sapiens] Length = 831 Score = 136 bits (343), Expect = 3e-32 Identities = 69/130 (53%), Positives = 88/130 (67%), Gaps = 6/130 (4%) Query: 291 CLKGPKLSEIG--TIAWMITLCDALHNFIDGLAIGASCTLSLLQGLSTSIAILCEEFPHE 348 C G L E G IAWM+ + D +HNF DGLAIGA+ + L G+STSIA+ C E PHE Sbjct: 655 CHSGSDLKETGIANIAWMVIMGDGIHNFSDGLAIGAAFSAGLTGGISTSIAVFCHELPHE 714 Query: 349 LGDFVILLNAGMSTRQALLFNFLSACSCYVGLAFGILVGNNFAPNI---IFALAGGMFLY 405 LGDF +LL AGM+ +QA+++N LSA Y+G+ G VG +A NI IFA+ GMFLY Sbjct: 715 LGDFAVLLKAGMTVKQAIVYNLLSAMMAYIGMLIGTAVG-QYANNITLWIFAVTAGMFLY 773 Query: 406 ISLADMFPEM 415 ++L DM PEM Sbjct: 774 VALVDMLPEM 783 Score = 87.8 bits (216), Expect = 2e-17 Identities = 58/195 (29%), Positives = 90/195 (46%), Gaps = 38/195 (19%) Query: 70 HFNQCLTAEEIFSLHGFSNATQITSSKFSVICPAVLQQLNFHPC---------EDRPKHK 120 H ++CL ++ +G + I++ F+ +CPA+L Q++ C ED K K Sbjct: 333 HHHECLNVTQLLKYYGHGANSPISTDLFTYLCPALLYQIDSRLCIEHFDKLLVEDINKDK 392 Query: 121 TRPSHSEV------WGYGFLSVTIINLASLLGLILTPLIKKSYFPKILTFFVGLAIGTLF 174 E W G +S+T+I+L SLLG+IL P+I + F +LTF V LA+GT+ Sbjct: 393 NLVPEDEANIGASAWICGIISITVISLLSLLGVILVPIINQGCFKFLLTFLVALAVGTMS 452 Query: 175 SNAIFQLIPEAFG----------------------FDPKVDSYVEKAVAVFGGFYLLFFF 212 +A+ L+P + G F + D+ V K + GG YLLF Sbjct: 453 GDALLHLLPHSQGGHDHSHQHAHGHGHSHGHESNKFLEEYDA-VLKGLVALGGIYLLFII 511 Query: 213 ERMLKMLLKTYGQNG 227 E ++M Q G Sbjct: 512 EHCIRMFKHYKQQRG 526 >gi|55741750 solute carrier family 39 (zinc transporter), member 10 [Homo sapiens] Length = 831 Score = 136 bits (343), Expect = 3e-32 Identities = 69/130 (53%), Positives = 88/130 (67%), Gaps = 6/130 (4%) Query: 291 CLKGPKLSEIG--TIAWMITLCDALHNFIDGLAIGASCTLSLLQGLSTSIAILCEEFPHE 348 C G L E G IAWM+ + D +HNF DGLAIGA+ + L G+STSIA+ C E PHE Sbjct: 655 CHSGSDLKETGIANIAWMVIMGDGIHNFSDGLAIGAAFSAGLTGGISTSIAVFCHELPHE 714 Query: 349 LGDFVILLNAGMSTRQALLFNFLSACSCYVGLAFGILVGNNFAPNI---IFALAGGMFLY 405 LGDF +LL AGM+ +QA+++N LSA Y+G+ G VG +A NI IFA+ GMFLY Sbjct: 715 LGDFAVLLKAGMTVKQAIVYNLLSAMMAYIGMLIGTAVG-QYANNITLWIFAVTAGMFLY 773 Query: 406 ISLADMFPEM 415 ++L DM PEM Sbjct: 774 VALVDMLPEM 783 Score = 87.8 bits (216), Expect = 2e-17 Identities = 58/195 (29%), Positives = 90/195 (46%), Gaps = 38/195 (19%) Query: 70 HFNQCLTAEEIFSLHGFSNATQITSSKFSVICPAVLQQLNFHPC---------EDRPKHK 120 H ++CL ++ +G + I++ F+ +CPA+L Q++ C ED K K Sbjct: 333 HHHECLNVTQLLKYYGHGANSPISTDLFTYLCPALLYQIDSRLCIEHFDKLLVEDINKDK 392 Query: 121 TRPSHSEV------WGYGFLSVTIINLASLLGLILTPLIKKSYFPKILTFFVGLAIGTLF 174 E W G +S+T+I+L SLLG+IL P+I + F +LTF V LA+GT+ Sbjct: 393 NLVPEDEANIGASAWICGIISITVISLLSLLGVILVPIINQGCFKFLLTFLVALAVGTMS 452 Query: 175 SNAIFQLIPEAFG----------------------FDPKVDSYVEKAVAVFGGFYLLFFF 212 +A+ L+P + G F + D+ V K + GG YLLF Sbjct: 453 GDALLHLLPHSQGGHDHSHQHAHGHGHSHGHESNKFLEEYDA-VLKGLVALGGIYLLFII 511 Query: 213 ERMLKMLLKTYGQNG 227 E ++M Q G Sbjct: 512 EHCIRMFKHYKQQRG 526 >gi|153252214 solute carrier family 39 (zinc transporter), member 6 isoform 2 [Homo sapiens] Length = 433 Score = 132 bits (331), Expect = 8e-31 Identities = 63/115 (54%), Positives = 85/115 (73%), Gaps = 4/115 (3%) Query: 300 IGTIAWMITLCDALHNFIDGLAIGASCTLSLLQGLSTSIAILCEEFPHELGDFVILLNAG 359 + T+AWM+ + D LHNF DGLAIGA+ T L GLSTS+A+ C E PHELGDF +LL AG Sbjct: 317 VATLAWMVIMGDGLHNFSDGLAIGAAFTEGLSSGLSTSVAVFCHELPHELGDFAVLLKAG 376 Query: 360 MSTRQALLFNFLSACSCYVGLAFGILVGNNFAPNI---IFALAGGMFLYISLADM 411 M+ +QA+L+N LSA Y+G+A GI +G ++A N+ IFAL G+F+Y++L DM Sbjct: 377 MTVKQAVLYNALSAMLAYLGMATGIFIG-HYAENVSMWIFALTAGLFMYVALVDM 430 Score = 69.3 bits (168), Expect = 7e-12 Identities = 37/120 (30%), Positives = 65/120 (54%), Gaps = 6/120 (5%) Query: 92 ITSSKFSVICPAVLQQLNFHPCEDRPKHKTRP------SHSEVWGYGFLSVTIINLASLL 145 + +++F+ +CPA++ Q++ C K S W GF++++II+ SLL Sbjct: 7 LNATEFNYLCPAIINQIDARSCLIHTSEKKAEIPPKTYSLQIAWVGGFIAISIISFLSLL 66 Query: 146 GLILTPLIKKSYFPKILTFFVGLAIGTLFSNAIFQLIPEAFGFDPKVDSYVEKAVAVFGG 205 G+IL PL+ + +F +L+F V LA+GTL +A L+P + S+ E A+ + G Sbjct: 67 GVILVPLMNRVFFKFLLSFLVALAVGTLSGDAFLHLLPHSHASHHHSHSHEEPAMEMKRG 126 >gi|117553619 solute carrier family 39, member 7 [Homo sapiens] Length = 469 Score = 84.3 bits (207), Expect = 2e-16 Identities = 81/320 (25%), Positives = 129/320 (40%), Gaps = 46/320 (14%) Query: 128 VWGYGFLSVTIINLASLLGLILTPLIKKS-YFPKILTFFVGLAIGTLFSNAIFQLIPEAF 186 +W Y + +I+ A L L P+ S +L + A G L +A LIP A Sbjct: 134 LWAYALGATVLISAAPFFVLFLIPVESNSPRHRSLLQILLSFASGGLLGDAFLHLIPHAL 193 Query: 187 GFDPKVDSYVEK----------------AVAVFGGFYLLFFFERMLKMLLKTYGQN---G 227 +P +E+ + V G E+ ++ + +G + G Sbjct: 194 --EPHSHHTLEQPGHGHSHSGQGPILSVGLWVLSGIVAFLVVEKFVRHVKGGHGHSHGHG 251 Query: 228 HTHF---GNDNFGPQEKTHQPKALPAINGVTCYANPAVTEANGHIHFDNVSVVSLQDGKK 284 H H G+ G QE++ + K + E G S V +DG Sbjct: 252 HAHSHTRGSHGHGRQERSTKEKQS---------SEEEEKETRGVQKRRGGSTVP-KDGPV 301 Query: 285 EPSSCTCLKGPKLSEIGTIAWMITLCDALHNFIDGLAIGASCTLSLLQGLSTSIAILCEE 344 P + K + ++ ++ D HNF DGLAIGAS G+ T++ +L E Sbjct: 302 RPQNAEEEK--RGLDLRVSGYLNLAADLAHNFTDGLAIGASFRGGRGLGILTTMTVLLHE 359 Query: 345 FPHELGDFVILLNAGMSTRQALLFNFLSACSCYVGLAFGIL-----VGNNFA----PNII 395 PHE+GDF IL+ +G S +QA+ L+A G A +L VG+ A P + Sbjct: 360 VPHEVGDFAILVQSGCSKKQAMRLQLLTAVGALAGTACALLTEGGAVGSEIAGGAGPGWV 419 Query: 396 FALAGGMFLYISLADMFPEM 415 G F+Y++ + PE+ Sbjct: 420 LPFTAGGFIYVATVSVLPEL 439 >gi|117553608 solute carrier family 39, member 7 [Homo sapiens] Length = 469 Score = 84.3 bits (207), Expect = 2e-16 Identities = 81/320 (25%), Positives = 129/320 (40%), Gaps = 46/320 (14%) Query: 128 VWGYGFLSVTIINLASLLGLILTPLIKKS-YFPKILTFFVGLAIGTLFSNAIFQLIPEAF 186 +W Y + +I+ A L L P+ S +L + A G L +A LIP A Sbjct: 134 LWAYALGATVLISAAPFFVLFLIPVESNSPRHRSLLQILLSFASGGLLGDAFLHLIPHAL 193 Query: 187 GFDPKVDSYVEK----------------AVAVFGGFYLLFFFERMLKMLLKTYGQN---G 227 +P +E+ + V G E+ ++ + +G + G Sbjct: 194 --EPHSHHTLEQPGHGHSHSGQGPILSVGLWVLSGIVAFLVVEKFVRHVKGGHGHSHGHG 251 Query: 228 HTHF---GNDNFGPQEKTHQPKALPAINGVTCYANPAVTEANGHIHFDNVSVVSLQDGKK 284 H H G+ G QE++ + K + E G S V +DG Sbjct: 252 HAHSHTRGSHGHGRQERSTKEKQS---------SEEEEKETRGVQKRRGGSTVP-KDGPV 301 Query: 285 EPSSCTCLKGPKLSEIGTIAWMITLCDALHNFIDGLAIGASCTLSLLQGLSTSIAILCEE 344 P + K + ++ ++ D HNF DGLAIGAS G+ T++ +L E Sbjct: 302 RPQNAEEEK--RGLDLRVSGYLNLAADLAHNFTDGLAIGASFRGGRGLGILTTMTVLLHE 359 Query: 345 FPHELGDFVILLNAGMSTRQALLFNFLSACSCYVGLAFGIL-----VGNNFA----PNII 395 PHE+GDF IL+ +G S +QA+ L+A G A +L VG+ A P + Sbjct: 360 VPHEVGDFAILVQSGCSKKQAMRLQLLTAVGALAGTACALLTEGGAVGSEIAGGAGPGWV 419 Query: 396 FALAGGMFLYISLADMFPEM 415 G F+Y++ + PE+ Sbjct: 420 LPFTAGGFIYVATVSVLPEL 439 >gi|40255101 solute carrier family 39 (zinc transporter), member 13 isoform b [Homo sapiens] Length = 364 Score = 73.9 bits (180), Expect = 3e-13 Identities = 75/307 (24%), Positives = 117/307 (38%), Gaps = 57/307 (18%) Query: 127 EVWGYGFLSVTIINLASLLGLILTPL-----IKKSYFPKILTFFVGLAIGTLFSNAIFQL 181 + W L ++ L+ + L++ PL ++ L + A+G L N L Sbjct: 66 DTWICSLLGSLMVGLSGVFPLLVIPLEMGTMLRSEAGAWRLKQLLSFALGGLLGNVFLHL 125 Query: 182 IPEAFGFD---------PKVDSYVEKAVAVFGGFYLLFFFERMLKMLLKTYGQNGHTHFG 232 +PEA+ + + + + V G E KM L + + G Sbjct: 126 LPEAWAYTCSASPGGEGQSLQQQQQLGLWVIAGILTFLALE---KMFLDSKEE------G 176 Query: 233 NDNFGPQEKTHQPKALPAINGVTCYANPAVTEANGHIHFDNVSVVSLQDGKKEPSSCTCL 292 ++ T A A+NG C A PA EP + Sbjct: 177 TSQAPNKDPT---AAAAALNGGHCLAQPAA----------------------EPGLGAVV 211 Query: 293 KGPKLSEIGTIAWMITLCDALHNFIDGLAIGASCTLSLLQGLSTSIAILCEEFPHELGDF 352 + K+S ++ L + + NF GLA+ AS +S GL T++AIL E PHE+GDF Sbjct: 212 RSIKVS-----GYLNLLANTIDNFTHGLAVAASFLVSKKIGLLTTMAILLHEIPHEVGDF 266 Query: 353 VILLNAGMSTRQALLFNFLSACSCYVGLAFGILV----GNNFAPNIIFALAGGMFLYISL 408 ILL AG A +A +G F I G + G FLYI+L Sbjct: 267 AILLRAGFDRWSAAKLQLSTALGGLLGAGFAICTQSPKGVEETAAWVLPFTSGGFLYIAL 326 Query: 409 ADMFPEM 415 ++ P++ Sbjct: 327 VNVLPDL 333 >gi|190014617 solute carrier family 39 (zinc transporter), member 13 isoform a [Homo sapiens] Length = 371 Score = 71.6 bits (174), Expect = 1e-12 Identities = 77/314 (24%), Positives = 121/314 (38%), Gaps = 64/314 (20%) Query: 127 EVWGYGFLSVTIINLASLLGLILTPL-----IKKSYFPKILTFFVGLAIGTLFSNAIFQL 181 + W L ++ L+ + L++ PL ++ L + A+G L N L Sbjct: 66 DTWICSLLGSLMVGLSGVFPLLVIPLEMGTMLRSEAGAWRLKQLLSFALGGLLGNVFLHL 125 Query: 182 IPEAFGFD---------PKVDSYVEKAVAVFGGFYLLFFFERMLKMLLKTYGQNGHTHFG 232 +PEA+ + + + + V G E KM L + + G Sbjct: 126 LPEAWAYTCSASPGGEGQSLQQQQQLGLWVIAGILTFLALE---KMFLDSKEE------G 176 Query: 233 NDNFGPQEKTHQPKALPAINGVTCYANPAVTEANGHIHFDNVSVVSLQDGKKEPSSCTCL 292 ++ T A A+NG C A PA EP + Sbjct: 177 TSQAPNKDPT---AAAAALNGGHCLAQPAA----------------------EPGLGAVV 211 Query: 293 KGPKLSEIGTIAWMITLCDALHNFIDGLAIGASCTLSLLQGLSTSIAILCEEFPHELGDF 352 + K+S ++ L + + NF GLA+ AS +S GL T++AIL E PHE+GDF Sbjct: 212 RSIKVS-----GYLNLLANTIDNFTHGLAVAASFLVSKKIGLLTTMAILLHEIPHEVGDF 266 Query: 353 VILLNAGMSTRQALLFNFLSACSCYVGLAFGI-------LVGNNFAPN----IIFALAGG 401 ILL AG A +A +G F I +VG + A + G Sbjct: 267 AILLRAGFDRWSAAKLQLSTALGGLLGAGFAICTQSPKGVVGCSPAAEETAAWVLPFTSG 326 Query: 402 MFLYISLADMFPEM 415 FLYI+L ++ P++ Sbjct: 327 GFLYIALVNVLPDL 340 >gi|229577422 solute carrier family 39, member 11 isoform 1 [Homo sapiens] Length = 342 Score = 46.2 bits (108), Expect = 6e-05 Identities = 41/147 (27%), Positives = 64/147 (43%), Gaps = 17/147 (11%) Query: 297 LSEIGTIAW----MITLCDALHNFIDGLAIG---------ASCTLSLLQGLSTSIAILCE 343 L++ G +W ++ L +HN +GLA+G AS T + L+ I I + Sbjct: 183 LAQPGGSSWRRIALLILAITIHNVPEGLAVGVGFGAIEKTASATFESARNLAIGIGI--Q 240 Query: 344 EFPHELGDFVILLNAGMSTRQALLFNFLSACSCYVGLAFGILVGNNFAPNIIFALA--GG 401 FP L + L AG ST +A + LS + FG P + +ALA G Sbjct: 241 NFPEGLAVSLPLRGAGFSTWRAFWYGQLSGMVEPLAGVFGAFAVVLAEPILPYALAFAAG 300 Query: 402 MFLYISLADMFPEMNDMLREKIIKWAT 428 +Y+ + D+ PE K+ WA+ Sbjct: 301 AMVYVVMDDIIPEAQISGNGKLASWAS 327 >gi|229577418 solute carrier family 39, member 11 isoform 2 [Homo sapiens] Length = 335 Score = 46.2 bits (108), Expect = 6e-05 Identities = 41/147 (27%), Positives = 64/147 (43%), Gaps = 17/147 (11%) Query: 297 LSEIGTIAW----MITLCDALHNFIDGLAIG---------ASCTLSLLQGLSTSIAILCE 343 L++ G +W ++ L +HN +GLA+G AS T + L+ I I + Sbjct: 176 LAQPGGSSWRRIALLILAITIHNVPEGLAVGVGFGAIEKTASATFESARNLAIGIGI--Q 233 Query: 344 EFPHELGDFVILLNAGMSTRQALLFNFLSACSCYVGLAFGILVGNNFAPNIIFALA--GG 401 FP L + L AG ST +A + LS + FG P + +ALA G Sbjct: 234 NFPEGLAVSLPLRGAGFSTWRAFWYGQLSGMVEPLAGVFGAFAVVLAEPILPYALAFAAG 293 Query: 402 MFLYISLADMFPEMNDMLREKIIKWAT 428 +Y+ + D+ PE K+ WA+ Sbjct: 294 AMVYVVMDDIIPEAQISGNGKLASWAS 320 >gi|156415986 solute carrier family 39 (zinc transporter), member 2 [Homo sapiens] Length = 309 Score = 44.7 bits (104), Expect = 2e-04 Identities = 34/131 (25%), Positives = 61/131 (46%), Gaps = 9/131 (6%) Query: 304 AWMITLCDALHNFIDGLAIGASCTLSLLQGLSTSIAILCEEFPHELGDFVILLNAGMSTR 363 A ++ L + H+ +GLA+G T++ L +A+L + G + L++ G S+R Sbjct: 165 ALVLLLSLSFHSVFEGLAVGLQPTVAATVQLC--LAVLAHKGLVVFGVGMRLVHLGTSSR 222 Query: 364 QALLFNFLSACSCYVGLAFGILV-------GNNFAPNIIFALAGGMFLYISLADMFPEMN 416 A+ L A +GLA G+ V G A ++ +A G FLY++ ++ P Sbjct: 223 WAVFSILLLALMSPLGLAVGLAVTGGDSEGGRGLAQAVLEGVAAGTFLYVTFLEILPREL 282 Query: 417 DMLREKIIKWA 427 + KW+ Sbjct: 283 ASPEAPLAKWS 293 >gi|21361423 solute carrier family 39 (zinc transporter), member 1 [Homo sapiens] Length = 324 Score = 35.4 bits (80), Expect = 0.10 Identities = 25/120 (20%), Positives = 55/120 (45%), Gaps = 8/120 (6%) Query: 312 ALHNFIDGLAIGASCTLSLLQGLSTSIAILCEEFPHELGDFVILLNAGMSTRQALLFNFL 371 ALH+ +GLA+G + + + +A+L + + + LL + + + L Sbjct: 188 ALHSVFEGLAVGLQRDRA--RAMELCLALLLHKGILAVSLSLRLLQSHLRAQVVAGCGIL 245 Query: 372 SACSCYVGLAFGILVGNNFAP------NIIFALAGGMFLYISLADMFPEMNDMLREKIIK 425 +C +G+ G + + P +++ +A G FLYI+ ++ P+ ++I+K Sbjct: 246 FSCMTPLGIGLGAALAESAGPLHQLAQSVLEGMAAGTFLYITFLEILPQELASSEQRILK 305 >gi|40254928 solute carrier family 39 (zinc transporter), member 9 [Homo sapiens] Length = 307 Score = 33.5 bits (75), Expect = 0.40 Identities = 32/118 (27%), Positives = 54/118 (45%), Gaps = 10/118 (8%) Query: 308 TLCDALHNFIDGLAIGASCTLSLLQ-GLSTSIAILCEEFPHELGDFVILLNAGMST---R 363 TL +H DG+A+GA+ + S L +AI+ + P G L++AG+ R Sbjct: 149 TLGLVVHAAADGVALGAAASTSQTSVQLIVFVAIMLHKAPAAFGLVSFLMHAGLERNRIR 208 Query: 364 QALLFNFLSA----CSCYVGLAFGI--LVGNNFAPNIIFALAGGMFLYISLADMFPEM 415 + LL L+A Y+GL+ + A + + G FLY++ + PE+ Sbjct: 209 KHLLVFALAAPVMSMVTYLGLSKSSKEALSEVNATGVAMLFSAGTFLYVATVHVLPEV 266 >gi|169160919 PREDICTED: hypothetical protein [Homo sapiens] Length = 404 Score = 30.8 bits (68), Expect = 2.6 Identities = 18/73 (24%), Positives = 30/73 (41%), Gaps = 8/73 (10%) Query: 64 PEPGQLHFNQCLTAEEIFSLHGF--------SNATQITSSKFSVICPAVLQQLNFHPCED 115 P+P ++CL + + L ++ Q + + I P LN P Sbjct: 31 PQPTNCPSSKCLVLQALHPLQRVFKEVITPSASPEQFFRGEEASIAPGKTNLLNTPPTSG 90 Query: 116 RPKHKTRPSHSEV 128 PKH+ PSHS++ Sbjct: 91 NPKHQRLPSHSQI 103 >gi|169162159 PREDICTED: hypothetical protein [Homo sapiens] Length = 404 Score = 30.8 bits (68), Expect = 2.6 Identities = 18/73 (24%), Positives = 30/73 (41%), Gaps = 8/73 (10%) Query: 64 PEPGQLHFNQCLTAEEIFSLHGF--------SNATQITSSKFSVICPAVLQQLNFHPCED 115 P+P ++CL + + L ++ Q + + I P LN P Sbjct: 31 PQPTNCPSSKCLVLQALHPLQRVFKEVITPSASPEQFFRGEEASIAPGKTNLLNTPPTSG 90 Query: 116 RPKHKTRPSHSEV 128 PKH+ PSHS++ Sbjct: 91 NPKHQRLPSHSQI 103 >gi|169161152 PREDICTED: hypothetical protein [Homo sapiens] Length = 404 Score = 30.8 bits (68), Expect = 2.6 Identities = 18/73 (24%), Positives = 30/73 (41%), Gaps = 8/73 (10%) Query: 64 PEPGQLHFNQCLTAEEIFSLHGF--------SNATQITSSKFSVICPAVLQQLNFHPCED 115 P+P ++CL + + L ++ Q + + I P LN P Sbjct: 31 PQPTNCPSSKCLVLQALHPLQRVFKEVITPSASPEQFFRGEEASIAPGKTNLLNTPPTSG 90 Query: 116 RPKHKTRPSHSEV 128 PKH+ PSHS++ Sbjct: 91 NPKHQRLPSHSQI 103 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.324 0.140 0.426 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 16,764,471 Number of Sequences: 37866 Number of extensions: 707777 Number of successful extensions: 2012 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 26 Number of HSP's successfully gapped in prelim test: 9 Number of HSP's that attempted gapping in prelim test: 1905 Number of HSP's gapped (non-prelim): 62 length of query: 444 length of database: 18,247,518 effective HSP length: 105 effective length of query: 339 effective length of database: 14,271,588 effective search space: 4838068332 effective search space used: 4838068332 T: 11 A: 40 X1: 15 ( 7.0 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.5 bits) S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.