Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 20336242
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|20336242 proprotein convertase subtilisin/kexin type 1
preproprotein [Homo sapiens]
(753 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|20336242 proprotein convertase subtilisin/kexin type 1 prepro... 1558 0.0
gi|20336184 paired basic amino acid cleaving system 4 isoform h ... 600 e-171
gi|20336182 paired basic amino acid cleaving system 4 isoform g ... 600 e-171
gi|4505577 paired basic amino acid cleaving system 4 isoform a p... 600 e-171
gi|20336180 paired basic amino acid cleaving system 4 isoform b ... 600 e-171
gi|20336188 paired basic amino acid cleaving system 4 isoform e ... 583 e-166
gi|27894285 paired basic amino acid cleaving system 4 isoform f ... 583 e-166
gi|20336190 paired basic amino acid cleaving system 4 isoform d ... 583 e-166
gi|4505579 furin preproprotein [Homo sapiens] 577 e-164
gi|20336246 proprotein convertase subtilisin/kexin type 5 prepro... 574 e-163
gi|76443679 proprotein convertase subtilisin/kexin type 4 [Homo ... 549 e-156
gi|20336244 proprotein convertase subtilisin/kexin type 2 [Homo ... 515 e-146
gi|20336186 paired basic amino acid cleaving system 4 isoform c ... 480 e-135
gi|20336248 proprotein convertase subtilisin/kexin type 7 prepro... 425 e-119
gi|4506775 membrane-bound transcription factor site-1 protease p... 38 0.030
gi|63252863 BTB (POZ) domain containing 12 [Homo sapiens] 36 0.15
gi|109638751 ubiquitin specific protease 6 [Homo sapiens] 35 0.20
gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo sap... 33 0.97
gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo sap... 33 0.97
gi|31317307 proprotein convertase subtilisin/kexin type 9 prepro... 33 1.3
gi|28827782 zinc fingers and homeoboxes 3 [Homo sapiens] 32 1.7
gi|109134351 zinc finger and BTB domain containing 44 [Homo sapi... 32 1.7
gi|221139761 zinc finger protein 853 [Homo sapiens] 32 2.2
gi|88758580 cyclin L2 isoform A [Homo sapiens] 32 2.2
gi|38788274 bromodomain PHD finger transcription factor isoform ... 32 2.2
gi|145580582 uromodulin-like 1 isoform 2 precursor [Homo sapiens] 32 2.8
gi|58530876 melanoma antigen family C, 1 [Homo sapiens] 31 3.7
gi|21687218 CD300 molecule-like family member g [Homo sapiens] 31 4.8
gi|153792764 hypothetical protein LOC57624 [Homo sapiens] 30 6.3
gi|239753409 PREDICTED: similar to hCG1811893 [Homo sapiens] 30 6.3
>gi|20336242 proprotein convertase subtilisin/kexin type 1
preproprotein [Homo sapiens]
Length = 753
Score = 1558 bits (4033), Expect = 0.0
Identities = 753/753 (100%), Positives = 753/753 (100%)
Query: 1 MERRAWSLQCTAFVLFCAWCALNSAKAKRQFVNEWAAEIPGGPEAASAIAEELGYDLLGQ 60
MERRAWSLQCTAFVLFCAWCALNSAKAKRQFVNEWAAEIPGGPEAASAIAEELGYDLLGQ
Sbjct: 1 MERRAWSLQCTAFVLFCAWCALNSAKAKRQFVNEWAAEIPGGPEAASAIAEELGYDLLGQ 60
Query: 61 IGSLENHYLFKHKNHPRRSRRSAFHITKRLSDDDRVIWAEQQYEKERSKRSALRDSALNL 120
IGSLENHYLFKHKNHPRRSRRSAFHITKRLSDDDRVIWAEQQYEKERSKRSALRDSALNL
Sbjct: 61 IGSLENHYLFKHKNHPRRSRRSAFHITKRLSDDDRVIWAEQQYEKERSKRSALRDSALNL 120
Query: 121 FNDPMWNQQWYLQDTRMTAALPKLDLHVIPVWQKGITGKGVVITVLDDGLEWNHTDIYAN 180
FNDPMWNQQWYLQDTRMTAALPKLDLHVIPVWQKGITGKGVVITVLDDGLEWNHTDIYAN
Sbjct: 121 FNDPMWNQQWYLQDTRMTAALPKLDLHVIPVWQKGITGKGVVITVLDDGLEWNHTDIYAN 180
Query: 181 YDPEASYDFNDNDHDPFPRYDPTNENKHGTRCAGEIAMQANNHKCGVGVAYNSKVGGIRM 240
YDPEASYDFNDNDHDPFPRYDPTNENKHGTRCAGEIAMQANNHKCGVGVAYNSKVGGIRM
Sbjct: 181 YDPEASYDFNDNDHDPFPRYDPTNENKHGTRCAGEIAMQANNHKCGVGVAYNSKVGGIRM 240
Query: 241 LDGIVTDAIEASSIGFNPGHVDIYSASWGPNDDGKTVEGPGRLAQKAFEYGVKQGRQGKG 300
LDGIVTDAIEASSIGFNPGHVDIYSASWGPNDDGKTVEGPGRLAQKAFEYGVKQGRQGKG
Sbjct: 241 LDGIVTDAIEASSIGFNPGHVDIYSASWGPNDDGKTVEGPGRLAQKAFEYGVKQGRQGKG 300
Query: 301 SIFVWASGNGGRQGDNCDCDGYTDSIYTISISSASQQGLSPWYAEKCSSTLATSYSSGDY 360
SIFVWASGNGGRQGDNCDCDGYTDSIYTISISSASQQGLSPWYAEKCSSTLATSYSSGDY
Sbjct: 301 SIFVWASGNGGRQGDNCDCDGYTDSIYTISISSASQQGLSPWYAEKCSSTLATSYSSGDY 360
Query: 361 TDQRITSADLHNDCTETHTGTSASAPLAAGIFALALEANPNLTWRDMQHLVVWTSEYDPL 420
TDQRITSADLHNDCTETHTGTSASAPLAAGIFALALEANPNLTWRDMQHLVVWTSEYDPL
Sbjct: 361 TDQRITSADLHNDCTETHTGTSASAPLAAGIFALALEANPNLTWRDMQHLVVWTSEYDPL 420
Query: 421 ANNPGWKKNGAGLMVNSRFGFGLLNAKALVDLADPRTWRSVPEKKECVVKDNDFEPRALK 480
ANNPGWKKNGAGLMVNSRFGFGLLNAKALVDLADPRTWRSVPEKKECVVKDNDFEPRALK
Sbjct: 421 ANNPGWKKNGAGLMVNSRFGFGLLNAKALVDLADPRTWRSVPEKKECVVKDNDFEPRALK 480
Query: 481 ANGEVIIEIPTRACEGQENAIKSLEHVQFEATIEYSRRGDLHVTLTSAAGTSTVLLAERE 540
ANGEVIIEIPTRACEGQENAIKSLEHVQFEATIEYSRRGDLHVTLTSAAGTSTVLLAERE
Sbjct: 481 ANGEVIIEIPTRACEGQENAIKSLEHVQFEATIEYSRRGDLHVTLTSAAGTSTVLLAERE 540
Query: 541 RDTSPNGFKNWDFMSVHTWGENPIGTWTLRITDMSGRIQNEGRIVNWKLILHGTSSQPEH 600
RDTSPNGFKNWDFMSVHTWGENPIGTWTLRITDMSGRIQNEGRIVNWKLILHGTSSQPEH
Sbjct: 541 RDTSPNGFKNWDFMSVHTWGENPIGTWTLRITDMSGRIQNEGRIVNWKLILHGTSSQPEH 600
Query: 601 MKQPRVYTSYNTVQNDRRGVEKMVDPGEEQPTQENPKENTLVSKSPSSSSVGGRRDELEE 660
MKQPRVYTSYNTVQNDRRGVEKMVDPGEEQPTQENPKENTLVSKSPSSSSVGGRRDELEE
Sbjct: 601 MKQPRVYTSYNTVQNDRRGVEKMVDPGEEQPTQENPKENTLVSKSPSSSSVGGRRDELEE 660
Query: 661 GAPSQAMLRLLQSAFSKNSPPKQSPKKSPSAKLNIPYENFYEALEKLNKPSQLKDSEDSL 720
GAPSQAMLRLLQSAFSKNSPPKQSPKKSPSAKLNIPYENFYEALEKLNKPSQLKDSEDSL
Sbjct: 661 GAPSQAMLRLLQSAFSKNSPPKQSPKKSPSAKLNIPYENFYEALEKLNKPSQLKDSEDSL 720
Query: 721 YNDYVDVFYNTKPYKHRDDRLLQALVDILNEEN 753
YNDYVDVFYNTKPYKHRDDRLLQALVDILNEEN
Sbjct: 721 YNDYVDVFYNTKPYKHRDDRLLQALVDILNEEN 753
>gi|20336184 paired basic amino acid cleaving system 4 isoform h
preproprotein [Homo sapiens]
Length = 962
Score = 600 bits (1548), Expect = e-171
Identities = 305/593 (51%), Positives = 397/593 (66%), Gaps = 10/593 (1%)
Query: 13 FVLFCAWCALNSAKAKRQ-FVNEWAAEIPGGPEAASAIAEELGYDLLGQIGSLENHYLFK 71
++L A A SA R + N WA ++ GGP A +A GY LGQIG+LE++Y F
Sbjct: 51 WLLLLALPAACSAPPPRPVYTNHWAVQVLGGPAEADRVAAAHGYLNLGQIGNLEDYYHFY 110
Query: 72 HKNHPRRSRRSAFHITKRLSDDDRVIWAEQQYEKERSKRSALRDSALNLFNDPMWNQQWY 131
H +RS S+ L D +V W +QQ K R KR D FNDP+W+ WY
Sbjct: 111 HSKTFKRSTLSSRGPHTFLRMDPQVKWLQQQEVKRRVKRQVRSDPQALYFNDPIWSNMWY 170
Query: 132 LQDTRMTAALPKLDLHVIPVWQKGITGKGVVITVLDDGLEWNHTDIYANYDPEASYDFND 191
L + + +++V W++G TGK VV+T+LDDG+E NH D+ NYD ASYD N
Sbjct: 171 LHCGDKNSRC-RSEMNVQAAWKRGYTGKNVVVTILDDGIERNHPDLAPNYDSYASYDVNG 229
Query: 192 NDHDPFPRYDPTNENKHGTRCAGEIAMQANNHKCGVGVAYNSKVGGIRMLDGIVTDAIEA 251
ND+DP PRYD +NENKHGTRCAGE+A ANN C VG+AYN+K+GGIRMLDG VTD +EA
Sbjct: 230 NDYDPSPRYDASNENKHGTRCAGEVAASANNSYCIVGIAYNAKIGGIRMLDGDVTDVVEA 289
Query: 252 SSIGFNPGHVDIYSASWGPNDDGKTVEGPGRLAQKAFEYGVKQGRQGKGSIFVWASGNGG 311
S+G P ++DIYSASWGP+DDGKTV+GPGRLA++AFEYG+K+GRQG GSIFVWASGNGG
Sbjct: 290 KSLGIRPNYIDIYSASWGPDDDGKTVDGPGRLAKQAFEYGIKKGRQGLGSIFVWASGNGG 349
Query: 312 RQGDNCDCDGYTDSIYTISISSASQQGLSPWYAEKCSSTLATSYSSGDYTDQRITSADLH 371
R+GD C CDGYT+SIYTIS+SSA++ G PWY E+C+STLAT+YSSG + +++I + DL
Sbjct: 350 REGDYCSCDGYTNSIYTISVSSATENGYKPWYLEECASTLATTYSSGAFYERKIVTTDLR 409
Query: 372 NDCTETHTGTSASAPLAAGIFALALEANPNLTWRDMQHLVVWTSEYDPLANNPGWKKNGA 431
CT+ HTGTS SAP+ AGI ALALEAN LTWRD+QHL+V TS L + WK NGA
Sbjct: 410 QRCTDGHTGTSVSAPMVAGIIALALEANSQLTWRDVQHLLVKTSRPAHLKAS-DWKVNGA 468
Query: 432 GLMVNSRFGFGLLNAKALVDLADPRTWRSVPEKKECVVKDNDFEPRALKANGEVIIEIPT 491
G V+ +GFGL++A+ALV + + W +VP + CV +D PR++ + T
Sbjct: 469 GHKVSHFYGFGLVDAEALV--VEAKKWTAVPSQHMCVAA-SDKRPRSIPLVQVLRTTALT 525
Query: 492 RAC-EGQENAIKSLEHVQFEATIEYSRRGDLHVTLTSAAGTSTVLLAERERDTSPNGFKN 550
AC E + + LEHV +I + RRGDL + L S +GT + LLA+R D S GF N
Sbjct: 526 SACAEHSDQRVVYLEHVVVRTSISHPRRGDLQIYLVSPSGTKSQLLAKRLLDLSNEGFTN 585
Query: 551 WDFMSVHTWGENPIGTWTLRITDMSGRIQN---EGRIVNWKLILHGTSSQPEH 600
W+FM+VH WGE G WTL I D+ +++N +G++ W LIL+GT+ P H
Sbjct: 586 WEFMTVHCWGEKAEGQWTLEIQDLPSQVRNPEKQGKLKEWSLILYGTAEHPYH 638
>gi|20336182 paired basic amino acid cleaving system 4 isoform g
preproprotein [Homo sapiens]
Length = 975
Score = 600 bits (1548), Expect = e-171
Identities = 305/593 (51%), Positives = 397/593 (66%), Gaps = 10/593 (1%)
Query: 13 FVLFCAWCALNSAKAKRQ-FVNEWAAEIPGGPEAASAIAEELGYDLLGQIGSLENHYLFK 71
++L A A SA R + N WA ++ GGP A +A GY LGQIG+LE++Y F
Sbjct: 51 WLLLLALPAACSAPPPRPVYTNHWAVQVLGGPAEADRVAAAHGYLNLGQIGNLEDYYHFY 110
Query: 72 HKNHPRRSRRSAFHITKRLSDDDRVIWAEQQYEKERSKRSALRDSALNLFNDPMWNQQWY 131
H +RS S+ L D +V W +QQ K R KR D FNDP+W+ WY
Sbjct: 111 HSKTFKRSTLSSRGPHTFLRMDPQVKWLQQQEVKRRVKRQVRSDPQALYFNDPIWSNMWY 170
Query: 132 LQDTRMTAALPKLDLHVIPVWQKGITGKGVVITVLDDGLEWNHTDIYANYDPEASYDFND 191
L + + +++V W++G TGK VV+T+LDDG+E NH D+ NYD ASYD N
Sbjct: 171 LHCGDKNSRC-RSEMNVQAAWKRGYTGKNVVVTILDDGIERNHPDLAPNYDSYASYDVNG 229
Query: 192 NDHDPFPRYDPTNENKHGTRCAGEIAMQANNHKCGVGVAYNSKVGGIRMLDGIVTDAIEA 251
ND+DP PRYD +NENKHGTRCAGE+A ANN C VG+AYN+K+GGIRMLDG VTD +EA
Sbjct: 230 NDYDPSPRYDASNENKHGTRCAGEVAASANNSYCIVGIAYNAKIGGIRMLDGDVTDVVEA 289
Query: 252 SSIGFNPGHVDIYSASWGPNDDGKTVEGPGRLAQKAFEYGVKQGRQGKGSIFVWASGNGG 311
S+G P ++DIYSASWGP+DDGKTV+GPGRLA++AFEYG+K+GRQG GSIFVWASGNGG
Sbjct: 290 KSLGIRPNYIDIYSASWGPDDDGKTVDGPGRLAKQAFEYGIKKGRQGLGSIFVWASGNGG 349
Query: 312 RQGDNCDCDGYTDSIYTISISSASQQGLSPWYAEKCSSTLATSYSSGDYTDQRITSADLH 371
R+GD C CDGYT+SIYTIS+SSA++ G PWY E+C+STLAT+YSSG + +++I + DL
Sbjct: 350 REGDYCSCDGYTNSIYTISVSSATENGYKPWYLEECASTLATTYSSGAFYERKIVTTDLR 409
Query: 372 NDCTETHTGTSASAPLAAGIFALALEANPNLTWRDMQHLVVWTSEYDPLANNPGWKKNGA 431
CT+ HTGTS SAP+ AGI ALALEAN LTWRD+QHL+V TS L + WK NGA
Sbjct: 410 QRCTDGHTGTSVSAPMVAGIIALALEANSQLTWRDVQHLLVKTSRPAHLKAS-DWKVNGA 468
Query: 432 GLMVNSRFGFGLLNAKALVDLADPRTWRSVPEKKECVVKDNDFEPRALKANGEVIIEIPT 491
G V+ +GFGL++A+ALV + + W +VP + CV +D PR++ + T
Sbjct: 469 GHKVSHFYGFGLVDAEALV--VEAKKWTAVPSQHMCVAA-SDKRPRSIPLVQVLRTTALT 525
Query: 492 RAC-EGQENAIKSLEHVQFEATIEYSRRGDLHVTLTSAAGTSTVLLAERERDTSPNGFKN 550
AC E + + LEHV +I + RRGDL + L S +GT + LLA+R D S GF N
Sbjct: 526 SACAEHSDQRVVYLEHVVVRTSISHPRRGDLQIYLVSPSGTKSQLLAKRLLDLSNEGFTN 585
Query: 551 WDFMSVHTWGENPIGTWTLRITDMSGRIQN---EGRIVNWKLILHGTSSQPEH 600
W+FM+VH WGE G WTL I D+ +++N +G++ W LIL+GT+ P H
Sbjct: 586 WEFMTVHCWGEKAEGQWTLEIQDLPSQVRNPEKQGKLKEWSLILYGTAEHPYH 638
>gi|4505577 paired basic amino acid cleaving system 4 isoform a
preproprotein [Homo sapiens]
Length = 969
Score = 600 bits (1548), Expect = e-171
Identities = 305/593 (51%), Positives = 397/593 (66%), Gaps = 10/593 (1%)
Query: 13 FVLFCAWCALNSAKAKRQ-FVNEWAAEIPGGPEAASAIAEELGYDLLGQIGSLENHYLFK 71
++L A A SA R + N WA ++ GGP A +A GY LGQIG+LE++Y F
Sbjct: 51 WLLLLALPAACSAPPPRPVYTNHWAVQVLGGPAEADRVAAAHGYLNLGQIGNLEDYYHFY 110
Query: 72 HKNHPRRSRRSAFHITKRLSDDDRVIWAEQQYEKERSKRSALRDSALNLFNDPMWNQQWY 131
H +RS S+ L D +V W +QQ K R KR D FNDP+W+ WY
Sbjct: 111 HSKTFKRSTLSSRGPHTFLRMDPQVKWLQQQEVKRRVKRQVRSDPQALYFNDPIWSNMWY 170
Query: 132 LQDTRMTAALPKLDLHVIPVWQKGITGKGVVITVLDDGLEWNHTDIYANYDPEASYDFND 191
L + + +++V W++G TGK VV+T+LDDG+E NH D+ NYD ASYD N
Sbjct: 171 LHCGDKNSRC-RSEMNVQAAWKRGYTGKNVVVTILDDGIERNHPDLAPNYDSYASYDVNG 229
Query: 192 NDHDPFPRYDPTNENKHGTRCAGEIAMQANNHKCGVGVAYNSKVGGIRMLDGIVTDAIEA 251
ND+DP PRYD +NENKHGTRCAGE+A ANN C VG+AYN+K+GGIRMLDG VTD +EA
Sbjct: 230 NDYDPSPRYDASNENKHGTRCAGEVAASANNSYCIVGIAYNAKIGGIRMLDGDVTDVVEA 289
Query: 252 SSIGFNPGHVDIYSASWGPNDDGKTVEGPGRLAQKAFEYGVKQGRQGKGSIFVWASGNGG 311
S+G P ++DIYSASWGP+DDGKTV+GPGRLA++AFEYG+K+GRQG GSIFVWASGNGG
Sbjct: 290 KSLGIRPNYIDIYSASWGPDDDGKTVDGPGRLAKQAFEYGIKKGRQGLGSIFVWASGNGG 349
Query: 312 RQGDNCDCDGYTDSIYTISISSASQQGLSPWYAEKCSSTLATSYSSGDYTDQRITSADLH 371
R+GD C CDGYT+SIYTIS+SSA++ G PWY E+C+STLAT+YSSG + +++I + DL
Sbjct: 350 REGDYCSCDGYTNSIYTISVSSATENGYKPWYLEECASTLATTYSSGAFYERKIVTTDLR 409
Query: 372 NDCTETHTGTSASAPLAAGIFALALEANPNLTWRDMQHLVVWTSEYDPLANNPGWKKNGA 431
CT+ HTGTS SAP+ AGI ALALEAN LTWRD+QHL+V TS L + WK NGA
Sbjct: 410 QRCTDGHTGTSVSAPMVAGIIALALEANSQLTWRDVQHLLVKTSRPAHLKAS-DWKVNGA 468
Query: 432 GLMVNSRFGFGLLNAKALVDLADPRTWRSVPEKKECVVKDNDFEPRALKANGEVIIEIPT 491
G V+ +GFGL++A+ALV + + W +VP + CV +D PR++ + T
Sbjct: 469 GHKVSHFYGFGLVDAEALV--VEAKKWTAVPSQHMCVAA-SDKRPRSIPLVQVLRTTALT 525
Query: 492 RAC-EGQENAIKSLEHVQFEATIEYSRRGDLHVTLTSAAGTSTVLLAERERDTSPNGFKN 550
AC E + + LEHV +I + RRGDL + L S +GT + LLA+R D S GF N
Sbjct: 526 SACAEHSDQRVVYLEHVVVRTSISHPRRGDLQIYLVSPSGTKSQLLAKRLLDLSNEGFTN 585
Query: 551 WDFMSVHTWGENPIGTWTLRITDMSGRIQN---EGRIVNWKLILHGTSSQPEH 600
W+FM+VH WGE G WTL I D+ +++N +G++ W LIL+GT+ P H
Sbjct: 586 WEFMTVHCWGEKAEGQWTLEIQDLPSQVRNPEKQGKLKEWSLILYGTAEHPYH 638
>gi|20336180 paired basic amino acid cleaving system 4 isoform b
preproprotein [Homo sapiens]
Length = 956
Score = 600 bits (1548), Expect = e-171
Identities = 305/593 (51%), Positives = 397/593 (66%), Gaps = 10/593 (1%)
Query: 13 FVLFCAWCALNSAKAKRQ-FVNEWAAEIPGGPEAASAIAEELGYDLLGQIGSLENHYLFK 71
++L A A SA R + N WA ++ GGP A +A GY LGQIG+LE++Y F
Sbjct: 51 WLLLLALPAACSAPPPRPVYTNHWAVQVLGGPAEADRVAAAHGYLNLGQIGNLEDYYHFY 110
Query: 72 HKNHPRRSRRSAFHITKRLSDDDRVIWAEQQYEKERSKRSALRDSALNLFNDPMWNQQWY 131
H +RS S+ L D +V W +QQ K R KR D FNDP+W+ WY
Sbjct: 111 HSKTFKRSTLSSRGPHTFLRMDPQVKWLQQQEVKRRVKRQVRSDPQALYFNDPIWSNMWY 170
Query: 132 LQDTRMTAALPKLDLHVIPVWQKGITGKGVVITVLDDGLEWNHTDIYANYDPEASYDFND 191
L + + +++V W++G TGK VV+T+LDDG+E NH D+ NYD ASYD N
Sbjct: 171 LHCGDKNSRC-RSEMNVQAAWKRGYTGKNVVVTILDDGIERNHPDLAPNYDSYASYDVNG 229
Query: 192 NDHDPFPRYDPTNENKHGTRCAGEIAMQANNHKCGVGVAYNSKVGGIRMLDGIVTDAIEA 251
ND+DP PRYD +NENKHGTRCAGE+A ANN C VG+AYN+K+GGIRMLDG VTD +EA
Sbjct: 230 NDYDPSPRYDASNENKHGTRCAGEVAASANNSYCIVGIAYNAKIGGIRMLDGDVTDVVEA 289
Query: 252 SSIGFNPGHVDIYSASWGPNDDGKTVEGPGRLAQKAFEYGVKQGRQGKGSIFVWASGNGG 311
S+G P ++DIYSASWGP+DDGKTV+GPGRLA++AFEYG+K+GRQG GSIFVWASGNGG
Sbjct: 290 KSLGIRPNYIDIYSASWGPDDDGKTVDGPGRLAKQAFEYGIKKGRQGLGSIFVWASGNGG 349
Query: 312 RQGDNCDCDGYTDSIYTISISSASQQGLSPWYAEKCSSTLATSYSSGDYTDQRITSADLH 371
R+GD C CDGYT+SIYTIS+SSA++ G PWY E+C+STLAT+YSSG + +++I + DL
Sbjct: 350 REGDYCSCDGYTNSIYTISVSSATENGYKPWYLEECASTLATTYSSGAFYERKIVTTDLR 409
Query: 372 NDCTETHTGTSASAPLAAGIFALALEANPNLTWRDMQHLVVWTSEYDPLANNPGWKKNGA 431
CT+ HTGTS SAP+ AGI ALALEAN LTWRD+QHL+V TS L + WK NGA
Sbjct: 410 QRCTDGHTGTSVSAPMVAGIIALALEANSQLTWRDVQHLLVKTSRPAHLKAS-DWKVNGA 468
Query: 432 GLMVNSRFGFGLLNAKALVDLADPRTWRSVPEKKECVVKDNDFEPRALKANGEVIIEIPT 491
G V+ +GFGL++A+ALV + + W +VP + CV +D PR++ + T
Sbjct: 469 GHKVSHFYGFGLVDAEALV--VEAKKWTAVPSQHMCVAA-SDKRPRSIPLVQVLRTTALT 525
Query: 492 RAC-EGQENAIKSLEHVQFEATIEYSRRGDLHVTLTSAAGTSTVLLAERERDTSPNGFKN 550
AC E + + LEHV +I + RRGDL + L S +GT + LLA+R D S GF N
Sbjct: 526 SACAEHSDQRVVYLEHVVVRTSISHPRRGDLQIYLVSPSGTKSQLLAKRLLDLSNEGFTN 585
Query: 551 WDFMSVHTWGENPIGTWTLRITDMSGRIQN---EGRIVNWKLILHGTSSQPEH 600
W+FM+VH WGE G WTL I D+ +++N +G++ W LIL+GT+ P H
Sbjct: 586 WEFMTVHCWGEKAEGQWTLEIQDLPSQVRNPEKQGKLKEWSLILYGTAEHPYH 638
>gi|20336188 paired basic amino acid cleaving system 4 isoform e
preproprotein [Homo sapiens]
Length = 623
Score = 583 bits (1502), Expect = e-166
Identities = 296/570 (51%), Positives = 383/570 (67%), Gaps = 7/570 (1%)
Query: 13 FVLFCAWCALNSAKAKRQ-FVNEWAAEIPGGPEAASAIAEELGYDLLGQIGSLENHYLFK 71
++L A A SA R + N WA ++ GGP A +A GY LGQIG+LE++Y F
Sbjct: 51 WLLLLALPAACSAPPPRPVYTNHWAVQVLGGPAEADRVAAAHGYLNLGQIGNLEDYYHFY 110
Query: 72 HKNHPRRSRRSAFHITKRLSDDDRVIWAEQQYEKERSKRSALRDSALNLFNDPMWNQQWY 131
H +RS S+ L D +V W +QQ K R KR D FNDP+W+ WY
Sbjct: 111 HSKTFKRSTLSSRGPHTFLRMDPQVKWLQQQEVKRRVKRQVRSDPQALYFNDPIWSNMWY 170
Query: 132 LQDTRMTAALPKLDLHVIPVWQKGITGKGVVITVLDDGLEWNHTDIYANYDPEASYDFND 191
L + + +++V W++G TGK VV+T+LDDG+E NH D+ NYD ASYD N
Sbjct: 171 LHCGDKNSRC-RSEMNVQAAWKRGYTGKNVVVTILDDGIERNHPDLAPNYDSYASYDVNG 229
Query: 192 NDHDPFPRYDPTNENKHGTRCAGEIAMQANNHKCGVGVAYNSKVGGIRMLDGIVTDAIEA 251
ND+DP PRYD +NENKHGTRCAGE+A ANN C VG+AYN+K+GGIRMLDG VTD +EA
Sbjct: 230 NDYDPSPRYDASNENKHGTRCAGEVAASANNSYCIVGIAYNAKIGGIRMLDGDVTDVVEA 289
Query: 252 SSIGFNPGHVDIYSASWGPNDDGKTVEGPGRLAQKAFEYGVKQGRQGKGSIFVWASGNGG 311
S+G P ++DIYSASWGP+DDGKTV+GPGRLA++AFEYG+K+GRQG GSIFVWASGNGG
Sbjct: 290 KSLGIRPNYIDIYSASWGPDDDGKTVDGPGRLAKQAFEYGIKKGRQGLGSIFVWASGNGG 349
Query: 312 RQGDNCDCDGYTDSIYTISISSASQQGLSPWYAEKCSSTLATSYSSGDYTDQRITSADLH 371
R+GD C CDGYT+SIYTIS+SSA++ G PWY E+C+STLAT+YSSG + +++I + DL
Sbjct: 350 REGDYCSCDGYTNSIYTISVSSATENGYKPWYLEECASTLATTYSSGAFYERKIVTTDLR 409
Query: 372 NDCTETHTGTSASAPLAAGIFALALEANPNLTWRDMQHLVVWTSEYDPLANNPGWKKNGA 431
CT+ HTGTS SAP+ AGI ALALEAN LTWRD+QHL+V TS L + WK NGA
Sbjct: 410 QRCTDGHTGTSVSAPMVAGIIALALEANSQLTWRDVQHLLVKTSRPAHLKAS-DWKVNGA 468
Query: 432 GLMVNSRFGFGLLNAKALVDLADPRTWRSVPEKKECVVKDNDFEPRALKANGEVIIEIPT 491
G V+ +GFGL++A+ALV + + W +VP + CV +D PR++ + T
Sbjct: 469 GHKVSHFYGFGLVDAEALV--VEAKKWTAVPSQHMCVAA-SDKRPRSIPLVQVLRTTALT 525
Query: 492 RAC-EGQENAIKSLEHVQFEATIEYSRRGDLHVTLTSAAGTSTVLLAERERDTSPNGFKN 550
AC E + + LEHV +I + RRGDL + L S +GT + LLA+R D S GF N
Sbjct: 526 SACAEHSDQRVVYLEHVVVRTSISHPRRGDLQIYLVSPSGTKSQLLAKRLLDLSNEGFTN 585
Query: 551 WDFMSVHTWGENPIGTWTLRITDMSGRIQN 580
W+FM+VH WGE G WTL I D+ +++N
Sbjct: 586 WEFMTVHCWGEKAEGQWTLEIQDLPSQVRN 615
>gi|27894285 paired basic amino acid cleaving system 4 isoform f
preproprotein [Homo sapiens]
Length = 664
Score = 583 bits (1502), Expect = e-166
Identities = 296/570 (51%), Positives = 383/570 (67%), Gaps = 7/570 (1%)
Query: 13 FVLFCAWCALNSAKAKRQ-FVNEWAAEIPGGPEAASAIAEELGYDLLGQIGSLENHYLFK 71
++L A A SA R + N WA ++ GGP A +A GY LGQIG+LE++Y F
Sbjct: 51 WLLLLALPAACSAPPPRPVYTNHWAVQVLGGPAEADRVAAAHGYLNLGQIGNLEDYYHFY 110
Query: 72 HKNHPRRSRRSAFHITKRLSDDDRVIWAEQQYEKERSKRSALRDSALNLFNDPMWNQQWY 131
H +RS S+ L D +V W +QQ K R KR D FNDP+W+ WY
Sbjct: 111 HSKTFKRSTLSSRGPHTFLRMDPQVKWLQQQEVKRRVKRQVRSDPQALYFNDPIWSNMWY 170
Query: 132 LQDTRMTAALPKLDLHVIPVWQKGITGKGVVITVLDDGLEWNHTDIYANYDPEASYDFND 191
L + + +++V W++G TGK VV+T+LDDG+E NH D+ NYD ASYD N
Sbjct: 171 LHCGDKNSRC-RSEMNVQAAWKRGYTGKNVVVTILDDGIERNHPDLAPNYDSYASYDVNG 229
Query: 192 NDHDPFPRYDPTNENKHGTRCAGEIAMQANNHKCGVGVAYNSKVGGIRMLDGIVTDAIEA 251
ND+DP PRYD +NENKHGTRCAGE+A ANN C VG+AYN+K+GGIRMLDG VTD +EA
Sbjct: 230 NDYDPSPRYDASNENKHGTRCAGEVAASANNSYCIVGIAYNAKIGGIRMLDGDVTDVVEA 289
Query: 252 SSIGFNPGHVDIYSASWGPNDDGKTVEGPGRLAQKAFEYGVKQGRQGKGSIFVWASGNGG 311
S+G P ++DIYSASWGP+DDGKTV+GPGRLA++AFEYG+K+GRQG GSIFVWASGNGG
Sbjct: 290 KSLGIRPNYIDIYSASWGPDDDGKTVDGPGRLAKQAFEYGIKKGRQGLGSIFVWASGNGG 349
Query: 312 RQGDNCDCDGYTDSIYTISISSASQQGLSPWYAEKCSSTLATSYSSGDYTDQRITSADLH 371
R+GD C CDGYT+SIYTIS+SSA++ G PWY E+C+STLAT+YSSG + +++I + DL
Sbjct: 350 REGDYCSCDGYTNSIYTISVSSATENGYKPWYLEECASTLATTYSSGAFYERKIVTTDLR 409
Query: 372 NDCTETHTGTSASAPLAAGIFALALEANPNLTWRDMQHLVVWTSEYDPLANNPGWKKNGA 431
CT+ HTGTS SAP+ AGI ALALEAN LTWRD+QHL+V TS L + WK NGA
Sbjct: 410 QRCTDGHTGTSVSAPMVAGIIALALEANSQLTWRDVQHLLVKTSRPAHLKAS-DWKVNGA 468
Query: 432 GLMVNSRFGFGLLNAKALVDLADPRTWRSVPEKKECVVKDNDFEPRALKANGEVIIEIPT 491
G V+ +GFGL++A+ALV + + W +VP + CV +D PR++ + T
Sbjct: 469 GHKVSHFYGFGLVDAEALV--VEAKKWTAVPSQHMCVAA-SDKRPRSIPLVQVLRTTALT 525
Query: 492 RAC-EGQENAIKSLEHVQFEATIEYSRRGDLHVTLTSAAGTSTVLLAERERDTSPNGFKN 550
AC E + + LEHV +I + RRGDL + L S +GT + LLA+R D S GF N
Sbjct: 526 SACAEHSDQRVVYLEHVVVRTSISHPRRGDLQIYLVSPSGTKSQLLAKRLLDLSNEGFTN 585
Query: 551 WDFMSVHTWGENPIGTWTLRITDMSGRIQN 580
W+FM+VH WGE G WTL I D+ +++N
Sbjct: 586 WEFMTVHCWGEKAEGQWTLEIQDLPSQVRN 615
>gi|20336190 paired basic amino acid cleaving system 4 isoform d
preproprotein [Homo sapiens]
Length = 652
Score = 583 bits (1502), Expect = e-166
Identities = 296/570 (51%), Positives = 383/570 (67%), Gaps = 7/570 (1%)
Query: 13 FVLFCAWCALNSAKAKRQ-FVNEWAAEIPGGPEAASAIAEELGYDLLGQIGSLENHYLFK 71
++L A A SA R + N WA ++ GGP A +A GY LGQIG+LE++Y F
Sbjct: 51 WLLLLALPAACSAPPPRPVYTNHWAVQVLGGPAEADRVAAAHGYLNLGQIGNLEDYYHFY 110
Query: 72 HKNHPRRSRRSAFHITKRLSDDDRVIWAEQQYEKERSKRSALRDSALNLFNDPMWNQQWY 131
H +RS S+ L D +V W +QQ K R KR D FNDP+W+ WY
Sbjct: 111 HSKTFKRSTLSSRGPHTFLRMDPQVKWLQQQEVKRRVKRQVRSDPQALYFNDPIWSNMWY 170
Query: 132 LQDTRMTAALPKLDLHVIPVWQKGITGKGVVITVLDDGLEWNHTDIYANYDPEASYDFND 191
L + + +++V W++G TGK VV+T+LDDG+E NH D+ NYD ASYD N
Sbjct: 171 LHCGDKNSRC-RSEMNVQAAWKRGYTGKNVVVTILDDGIERNHPDLAPNYDSYASYDVNG 229
Query: 192 NDHDPFPRYDPTNENKHGTRCAGEIAMQANNHKCGVGVAYNSKVGGIRMLDGIVTDAIEA 251
ND+DP PRYD +NENKHGTRCAGE+A ANN C VG+AYN+K+GGIRMLDG VTD +EA
Sbjct: 230 NDYDPSPRYDASNENKHGTRCAGEVAASANNSYCIVGIAYNAKIGGIRMLDGDVTDVVEA 289
Query: 252 SSIGFNPGHVDIYSASWGPNDDGKTVEGPGRLAQKAFEYGVKQGRQGKGSIFVWASGNGG 311
S+G P ++DIYSASWGP+DDGKTV+GPGRLA++AFEYG+K+GRQG GSIFVWASGNGG
Sbjct: 290 KSLGIRPNYIDIYSASWGPDDDGKTVDGPGRLAKQAFEYGIKKGRQGLGSIFVWASGNGG 349
Query: 312 RQGDNCDCDGYTDSIYTISISSASQQGLSPWYAEKCSSTLATSYSSGDYTDQRITSADLH 371
R+GD C CDGYT+SIYTIS+SSA++ G PWY E+C+STLAT+YSSG + +++I + DL
Sbjct: 350 REGDYCSCDGYTNSIYTISVSSATENGYKPWYLEECASTLATTYSSGAFYERKIVTTDLR 409
Query: 372 NDCTETHTGTSASAPLAAGIFALALEANPNLTWRDMQHLVVWTSEYDPLANNPGWKKNGA 431
CT+ HTGTS SAP+ AGI ALALEAN LTWRD+QHL+V TS L + WK NGA
Sbjct: 410 QRCTDGHTGTSVSAPMVAGIIALALEANSQLTWRDVQHLLVKTSRPAHLKAS-DWKVNGA 468
Query: 432 GLMVNSRFGFGLLNAKALVDLADPRTWRSVPEKKECVVKDNDFEPRALKANGEVIIEIPT 491
G V+ +GFGL++A+ALV + + W +VP + CV +D PR++ + T
Sbjct: 469 GHKVSHFYGFGLVDAEALV--VEAKKWTAVPSQHMCVAA-SDKRPRSIPLVQVLRTTALT 525
Query: 492 RAC-EGQENAIKSLEHVQFEATIEYSRRGDLHVTLTSAAGTSTVLLAERERDTSPNGFKN 550
AC E + + LEHV +I + RRGDL + L S +GT + LLA+R D S GF N
Sbjct: 526 SACAEHSDQRVVYLEHVVVRTSISHPRRGDLQIYLVSPSGTKSQLLAKRLLDLSNEGFTN 585
Query: 551 WDFMSVHTWGENPIGTWTLRITDMSGRIQN 580
W+FM+VH WGE G WTL I D+ +++N
Sbjct: 586 WEFMTVHCWGEKAEGQWTLEIQDLPSQVRN 615
>gi|4505579 furin preproprotein [Homo sapiens]
Length = 794
Score = 577 bits (1487), Expect = e-164
Identities = 307/608 (50%), Positives = 396/608 (65%), Gaps = 31/608 (5%)
Query: 1 MERRAWSLQCTA----FVLFCAWCALNSAKAKRQFVNEWAAEIPGGPEAASAIAEELGYD 56
ME R W L A VL A A+ ++ F N WA IPGGP A+++A + G+
Sbjct: 1 MELRPWLLWVVAATGTLVLLAA-----DAQGQKVFTNTWAVRIPGGPAVANSVARKHGFL 55
Query: 57 LLGQIGSLENHYLFKHKNHPRRSRRSAFHITKRLSDDDRVIWAEQQYEKERSKRSALRDS 116
LGQI ++Y F H+ +RS RL + +V W EQQ K R+KR ++
Sbjct: 56 NLGQI--FGDYYHFWHRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVAKRRTKRDVYQEP 113
Query: 117 ALNLFNDPMWNQQWYLQDTRMTAALPKLDLHVIPVWQKGITGKGVVITVLDDGLEWNHTD 176
DP + QQWYL + + + DL+V W +G TG G+V+++LDDG+E NH D
Sbjct: 114 T-----DPKFPQQWYL------SGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPD 162
Query: 177 IYANYDPEASYDFNDNDHDPFPRYDPTNENKHGTRCAGEIAMQANNHKCGVGVAYNSKVG 236
+ NYDP AS+D ND D DP PRY N+N+HGTRCAGE+A ANN CGVGVAYN+++G
Sbjct: 163 LAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIG 222
Query: 237 GIRMLDGIVTDAIEASSIGFNPGHVDIYSASWGPNDDGKTVEGPGRLAQKAFEYGVKQGR 296
G+RMLDG VTDA+EA S+G NP H+ IYSASWGP DDGKTV+GP RLA++AF GV QGR
Sbjct: 223 GVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGR 282
Query: 297 QGKGSIFVWASGNGGRQGDNCDCDGYTDSIYTISISSASQQGLSPWYAEKCSSTLATSYS 356
G GSIFVWASGNGGR+ D+C+CDGYT+SIYT+SISSA+Q G PWY+E CSSTLAT+YS
Sbjct: 283 GGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYS 342
Query: 357 SGDYTDQRITSADLHNDCTETHTGTSASAPLAAGIFALALEANPNLTWRDMQHLVVWTSE 416
SG+ +++I + DL CTE+HTGTSASAPLAAGI AL LEAN NLTWRDMQHLVV TS+
Sbjct: 343 SGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSK 402
Query: 417 YDPLANNPGWKKNGAGLMVNSRFGFGLLNAKALVDLADPRTWRSVPEKKECVVKDNDFEP 476
L N W NG G V+ +G+GLL+A A+V LA + W +V +++C++ D EP
Sbjct: 403 PAHL-NANDWATNGVGRKVSHSYGYGLLDAGAMVALA--QNWTTVAPQRKCII-DILTEP 458
Query: 477 RALKANGEVIIEIPTRACEGQENAIKSLEHVQFEATIEYSRRGDLHVTLTSAAGTSTVLL 536
+ + EV AC G+ N I LEH Q T+ Y+RRGDL + L S GT + LL
Sbjct: 459 KDIGKRLEV--RKTVTACLGEPNHITRLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTLL 516
Query: 537 AERERDTSPNGFKNWDFMSVHTWGENPIGTWTLRITDMSGRIQNEGRIVNWKLILHGTSS 596
A R D S +GF +W FM+ H+W E+P G W L I + S N G + + L+L+GT+
Sbjct: 517 AARPHDYSADGFNDWAFMTTHSWDEDPSGEWVLEIENTS-EANNYGTLTKFTLVLYGTA- 574
Query: 597 QPEHMKQP 604
PE + P
Sbjct: 575 -PEGLPVP 581
>gi|20336246 proprotein convertase subtilisin/kexin type 5
preproprotein [Homo sapiens]
Length = 913
Score = 574 bits (1479), Expect = e-163
Identities = 299/629 (47%), Positives = 396/629 (62%), Gaps = 22/629 (3%)
Query: 29 RQFVNEWAAEIPGGPEAASAIAEELGYDLLGQIGSLENHYLFKHKNHPRRSRRSAFHITK 88
R + N WA +I GG A+ IA + G+ +GQIG+L+++Y F H +RS S+
Sbjct: 33 RVYTNHWAVKIAGGFPEANRIASKYGFINIGQIGALKDYYHFYHSRTIKRSVISSRGTHS 92
Query: 89 RLSDDDRVIWAEQQYEKERSKRSALRDSALNL-FNDPMWNQQWYLQDTRMTAALPKLDLH 147
+S + +V W +QQ K+R+KR A + FNDP W WY+ + T D++
Sbjct: 93 FISMEPKVEWIQQQVVKKRTKRDYDFSRAQSTYFNDPKWPSMWYMHCSDNTHPCQS-DMN 151
Query: 148 VIPVWQKGITGKGVVITVLDDGLEWNHTDIYANYDPEASYDFNDNDHDPFPRYDPTNENK 207
+ W++G TGK +V+T+LDDG+E H D+ NYD AS D N ND DP PRYD +NENK
Sbjct: 152 IEGAWKRGYTGKNIVVTILDDGIERTHPDLMQNYDALASCDVNGNDLDPMPRYDASNENK 211
Query: 208 HGTRCAGEIAMQANNHKCGVGVAYNSKVGGIRMLDGIVTDAIEASSIGFNPGHVDIYSAS 267
HGTRCAGE+A ANN C VG+A+N+K+GG+RMLDG VTD +EA S+ FNP HV IYSAS
Sbjct: 212 HGTRCAGEVAAAANNSHCTVGIAFNAKIGGVRMLDGDVTDMVEAKSVSFNPQHVHIYSAS 271
Query: 268 WGPNDDGKTVEGPGRLAQKAFEYGVKQGRQGKGSIFVWASGNGGRQGDNCDCDGYTDSIY 327
WGP+DDGKTV+GP L ++AFE GV+ GR+G GS+FVWASGNGGR D+C CDGYT+SIY
Sbjct: 272 WGPDDDGKTVDGPAPLTRQAFENGVRMGRRGLGSVFVWASGNGGRSKDHCSCDGYTNSIY 331
Query: 328 TISISSASQQGLSPWYAEKCSSTLATSYSSGDYTDQRITSADLHNDCTETHTGTSASAPL 387
TISISS ++ G PWY E+CSSTLAT+YSSG+ D++I + DL CT+ HTGTSASAP+
Sbjct: 332 TISISSTAESGKKPWYLEECSSTLATTYSSGESYDKKIITTDLRQRCTDNHTGTSASAPM 391
Query: 388 AAGIFALALEANPNLTWRDMQHLVVWTSEYDPLANNPGWKKNGAGLMVNSRFGFGLLNAK 447
AAGI ALALEANP LTWRD+QH++V TS L N WK N AG V+ +GFGL++A+
Sbjct: 392 AAGIIALALEANPFLTWRDVQHVIVRTSRAGHL-NANDWKTNAAGFKVSHLYGFGLMDAE 450
Query: 448 ALVDLADPRTWRSVPEKKECVVKDNDFEPRALKANGEVIIEIPTRACEGQENA-IKSLEH 506
A+V + W +VP + C V+ D + + ++ N V C N + LEH
Sbjct: 451 AMV--MEAEKWTTVPRQHVC-VESTDRQIKTIRPNSAVRSIYKASGCSDNPNRHVNYLEH 507
Query: 507 VQFEATIEYSRRGDLHVTLTSAAGTSTVLLAERERDTSPNGFKNWDFMSVHTWGENPIGT 566
V TI + RRGDL + LTS +GT + LLA R D S GFKNW+FM++H WGE G
Sbjct: 508 VVVRITITHPRRGDLAIYLTSPSGTRSQLLANRLFDHSMEGFKNWEFMTIHCWGERAAGD 567
Query: 567 WTLRITDMSGRIQN---EGRIVNWKLILHGTSSQPEHMKQPRVYTSYNTVQNDRRGVEKM 623
W L + D +++N G++ W L+L+GTS QP + N+ VE+
Sbjct: 568 WVLEVYDTPSQLRNFKTPGKLKEWSLVLYGTSVQP------------YSPTNEFPKVERF 615
Query: 624 VDPGEEQPTQENPKENTLVSKSPSSSSVG 652
E PT + E+ P S VG
Sbjct: 616 RYSRVEDPTDDYGTEDYAGPCDPECSEVG 644
>gi|76443679 proprotein convertase subtilisin/kexin type 4 [Homo
sapiens]
Length = 755
Score = 549 bits (1414), Expect = e-156
Identities = 280/595 (47%), Positives = 381/595 (64%), Gaps = 19/595 (3%)
Query: 31 FVNEWAAEIPGGPEAASAIAEELGYDLLGQIGSLENHYLFKHKNHPRRSRRSAFHITKRL 90
+V+ WA ++ G +A + G+ LG I ++ +H+ ++S + L
Sbjct: 34 YVSSWAVQVSQGNREVERLARKFGFVNLGPIFPDGQYFHLRHRGVVQQSLTPHWGHRLHL 93
Query: 91 SDDDRVIWAEQQYEKERSKRSALRDSALNLFNDPMWNQQWYLQDTRMTAALPKLDLHVIP 150
+ +V W +QQ + R KRS + + DP +++QWY+ + A P DL ++
Sbjct: 94 KKNPKVQWFQQQTLQRRVKRSVVVPT------DPWFSKQWYMN----SEAQP--DLSILQ 141
Query: 151 VWQKGITGKGVVITVLDDGLEWNHTDIYANYDPEASYDFNDNDHDPFPRYDPTNENKHGT 210
W +G++G+G+V++VLDDG+E +H D++ANYDP ASYDFND D DP PRY P+ EN+HGT
Sbjct: 142 AWSQGLSGQGIVVSVLDDGIEKDHPDLWANYDPLASYDFNDYDPDPQPRYTPSKENRHGT 201
Query: 211 RCAGEIAMQANNHKCGVGVAYNSKVGGIRMLDGIVTDAIEASSIGFNPGHVDIYSASWGP 270
RCAGE+A ANN CGVGVA+N+++GG+RMLDG +TD IEA S+ P H+ IYSASWGP
Sbjct: 202 RCAGEVAAMANNGFCGVGVAFNARIGGVRMLDGTITDVIEAQSLSLQPQHIHIYSASWGP 261
Query: 271 NDDGKTVEGPGRLAQKAFEYGVKQGRQGKGSIFVWASGNGGRQGDNCDCDGYTDSIYTIS 330
DDG+TV+GPG L ++AF GV +GR G G++F+WASGNGG DNC+CDGYT+SI+T+S
Sbjct: 262 EDDGRTVDGPGILTREAFRRGVTKGRGGLGTLFIWASGNGGLHYDNCNCDGYTNSIHTLS 321
Query: 331 ISSASQQGLSPWYAEKCSSTLATSYSSGDYTDQRITSADLHNDCTETHTGTSASAPLAAG 390
+ S +QQG PWY+E C+STL T+YSSG TD +I + DLH+ CT+ HTGTSASAPLAAG
Sbjct: 322 VGSTTQQGRVPWYSEACASTLTTTYSSGVATDPQIVTTDLHHGCTDQHTGTSASAPLAAG 381
Query: 391 IFALALEANPNLTWRDMQHLVVWTSEYDPLANNPGWKKNGAGLMVNSRFGFGLLNAKALV 450
+ ALALEANP LTWRDMQHLVV S+ L W+ NG G V+ +G+GLL+A LV
Sbjct: 382 MIALALEANPFLTWRDMQHLVVRASKPAHL-QAEDWRTNGVGRQVSHHYGYGLLDAGLLV 440
Query: 451 DLADPRTWRSVPEKKECVVKDNDFEPRALKANGEVIIEIPTRACEGQENAIKSLEHVQFE 510
D A RTW +++C V+ + R + I AC G N+I+SLEHVQ +
Sbjct: 441 DTA--RTWLPTQPQRKCAVR---VQSRPTPILPLIYIRENVSACAGLHNSIRSLEHVQAQ 495
Query: 511 ATIEYSRRGDLHVTLTSAAGTSTVLLAERERDTSPNGFKNWDFMSVHTWGENPIGTWTLR 570
T+ YSRRGDL ++LTS GT + L+A R D S G+ NW FMS H W ENP G WTL
Sbjct: 496 LTLSYSRRGDLEISLTSPMGTRSTLVAIRPLDVSTEGYNNWVFMSTHFWDENPQGVWTLG 555
Query: 571 ITDMSGRIQNEGRIVNWKLILHGTSSQPEHMKQPRVYTSYNTVQNDRRGVEKMVD 625
+ + G N G + + L+L+GT+ TS VQ D G+ + D
Sbjct: 556 L-ENKGYYFNTGTLYRYTLLLYGTAEDMTARPTGPQVTSSACVQRDTEGLCQACD 609
>gi|20336244 proprotein convertase subtilisin/kexin type 2 [Homo
sapiens]
Length = 638
Score = 515 bits (1327), Expect = e-146
Identities = 282/620 (45%), Positives = 394/620 (63%), Gaps = 15/620 (2%)
Query: 19 WCALNSAKAKRQ-FVNEWAAEI-PGGPEAASAIAEELGYDLLGQIGSLENHYLFKHKNHP 76
+C + A A+R F N + E+ GG + A +A E G+ + ++ E Y F H
Sbjct: 17 FCVMVFASAERPVFTNHFLVELHKGGEDKARQVAAEHGFGVR-KLPFAEGLYHFYHNGLA 75
Query: 77 RRSRRSAFHITKRLSDDDRVIWAEQQYEKERSKRSALRDSALNL-FNDPMWNQQWYLQDT 135
+ RR + H ++L D RV A QQ +R KR + +++ NDP++ +QWYL +T
Sbjct: 76 KAKRRRSLHHKQQLERDPRVKMALQQEGFDRKKRGYRDINEIDINMNDPLFTKQWYLINT 135
Query: 136 RMTAALPKLDLHVIPVWQKGITGKGVVITVLDDGLEWNHTDIYANYDPEASYDFNDNDHD 195
P LDL+V W+ G TGKGV I ++DDG+++ H D+ +NY+ EASYDF+ ND
Sbjct: 136 GQADGTPGLDLNVAEAWELGYTGKGVTIGIMDDGIDYLHPDLASNYNAEASYDFSSNDPY 195
Query: 196 PFPRYDPTNENKHGTRCAGEIAMQANNHKCGVGVAYNSKVGGIRMLD-GIVTDAIEASSI 254
P+PRY N HGTRCAGE++ ANN+ CGVGVAYNSKV GIRMLD +TD IEASSI
Sbjct: 196 PYPRYTDDWFNSHGTRCAGEVSAAANNNICGVGVAYNSKVAGIRMLDQPFMTDIIEASSI 255
Query: 255 GFNPGHVDIYSASWGPNDDGKTVEGPGRLAQKAFEYGVKQGRQGKGSIFVWASGNGGRQG 314
P +DIYSASWGP D+GKTV+GP L +A GV +GR GKGSI+VWASG+GG
Sbjct: 256 SHMPQLIDIYSASWGPTDNGKTVDGPRELTLQAMADGVNKGRGGKGSIYVWASGDGGSY- 314
Query: 315 DNCDCDGYTDSIYTISISSASQQGLSPWYAEKCSSTLATSYSSGDYTDQR--ITSADLHN 372
D+C+CDGY S++TISI+SA G + Y E CSSTLA+++S+G + + + DL+
Sbjct: 315 DDCNCDGYASSMWTISINSAINDGRTALYDESCSSTLASTFSNGRKRNPEAGVATTDLYG 374
Query: 373 DCTETHTGTSASAPLAAGIFALALEANPNLTWRDMQHLVVWTSEYDPLANN-PGWKKNGA 431
+CT H+GTSA+AP AAG+FALALEAN LTWRDMQHL V TS+ + L + W++NG
Sbjct: 375 NCTLRHSGTSAAAPEAAGVFALALEANLGLTWRDMQHLTVLTSKRNQLHDEVHQWRRNGV 434
Query: 432 GLMVNSRFGFGLLNAKALVDLADPRTWRSVPEKKECVVKDNDFEPRALKANGEVIIEIPT 491
GL N FG+G+L+A A+V +A + W++VPE+ C V + +P + + G++++ + T
Sbjct: 435 GLEFNHLFGYGVLDAGAMVKMA--KDWKTVPERFHC-VGGSVQDPEKIPSTGKLVLTLTT 491
Query: 492 RACEGQENAIKSLEHVQFEATIEYSRRGDLHVTLTSAAGTSTVLLAERER-DTSPNGFKN 550
ACEG+EN ++ LEHVQ T+ +RRGDL++ +TS GT ++LL+ R R D S GF
Sbjct: 492 DACEGKENFVRYLEHVQAVITVNATRRGDLNINMTSPMGTKSILLSRRPRDDDSKVGFDK 551
Query: 551 WDFMSVHTWGENPIGTWTLRITDMSGRIQNEGRIVNWKLILHGTSSQPEHMKQPRVYTSY 610
W FM+ HTWGE+ GTWTL + G +G + W L+LHGT S P + R Y S
Sbjct: 552 WPFMTTHTWGEDARGTWTLEL-GFVGSAPQKGVLKEWTLMLHGTQSAPYIDQVVRDYQS- 609
Query: 611 NTVQNDRRGVEKMVDPGEEQ 630
+ + +E+ +D E+
Sbjct: 610 KLAMSKKEELEEELDEAVER 629
>gi|20336186 paired basic amino acid cleaving system 4 isoform c
preproprotein [Homo sapiens]
Length = 487
Score = 480 bits (1236), Expect = e-135
Identities = 237/421 (56%), Positives = 297/421 (70%), Gaps = 3/421 (0%)
Query: 13 FVLFCAWCALNSAKAKRQ-FVNEWAAEIPGGPEAASAIAEELGYDLLGQIGSLENHYLFK 71
++L A A SA R + N WA ++ GGP A +A GY LGQIG+LE++Y F
Sbjct: 51 WLLLLALPAACSAPPPRPVYTNHWAVQVLGGPAEADRVAAAHGYLNLGQIGNLEDYYHFY 110
Query: 72 HKNHPRRSRRSAFHITKRLSDDDRVIWAEQQYEKERSKRSALRDSALNLFNDPMWNQQWY 131
H +RS S+ L D +V W +QQ K R KR D FNDP+W+ WY
Sbjct: 111 HSKTFKRSTLSSRGPHTFLRMDPQVKWLQQQEVKRRVKRQVRSDPQALYFNDPIWSNMWY 170
Query: 132 LQDTRMTAALPKLDLHVIPVWQKGITGKGVVITVLDDGLEWNHTDIYANYDPEASYDFND 191
L + + +++V W++G TGK VV+T+LDDG+E NH D+ NYD ASYD N
Sbjct: 171 LHCGDKNSRC-RSEMNVQAAWKRGYTGKNVVVTILDDGIERNHPDLAPNYDSYASYDVNG 229
Query: 192 NDHDPFPRYDPTNENKHGTRCAGEIAMQANNHKCGVGVAYNSKVGGIRMLDGIVTDAIEA 251
ND+DP PRYD +NENKHGTRCAGE+A ANN C VG+AYN+K+GGIRMLDG VTD +EA
Sbjct: 230 NDYDPSPRYDASNENKHGTRCAGEVAASANNSYCIVGIAYNAKIGGIRMLDGDVTDVVEA 289
Query: 252 SSIGFNPGHVDIYSASWGPNDDGKTVEGPGRLAQKAFEYGVKQGRQGKGSIFVWASGNGG 311
S+G P ++DIYSASWGP+DDGKTV+GPGRLA++AFEYG+K+GRQG GSIFVWASGNGG
Sbjct: 290 KSLGIRPNYIDIYSASWGPDDDGKTVDGPGRLAKQAFEYGIKKGRQGLGSIFVWASGNGG 349
Query: 312 RQGDNCDCDGYTDSIYTISISSASQQGLSPWYAEKCSSTLATSYSSGDYTDQRITSADLH 371
R+GD C CDGYT+SIYTIS+SSA++ G PWY E+C+STLAT+YSSG + +++I + DL
Sbjct: 350 REGDYCSCDGYTNSIYTISVSSATENGYKPWYLEECASTLATTYSSGAFYERKIVTTDLR 409
Query: 372 NDCTETHTGTSASAPLAAGIFALALEANPNLTWRDMQHLVVWTSEYDPLANNPGWKKNGA 431
CT+ HTGTS SAP+ AGI ALALEAN LTWRD+QHL+V TS L + WK NGA
Sbjct: 410 QRCTDGHTGTSVSAPMVAGIIALALEANSQLTWRDVQHLLVKTSRPAHLKAS-DWKVNGA 468
Query: 432 G 432
G
Sbjct: 469 G 469
>gi|20336248 proprotein convertase subtilisin/kexin type 7
preproprotein [Homo sapiens]
Length = 785
Score = 425 bits (1092), Expect = e-119
Identities = 241/562 (42%), Positives = 333/562 (59%), Gaps = 29/562 (5%)
Query: 44 EAASAIAEELGYDLLGQIGSLENHYLF-KHKNHPRRSRRSAFH--ITKRLSDDDRVIWAE 100
+ A A+A+ G G+IG L+ HYLF + H A + L+ + V W
Sbjct: 72 QQADALAQAAGLVNAGRIGELQGHYLFVQPAGHRPALEVEAIRQQVEAVLAGHEAVRWHS 131
Query: 101 QQYEKERSKRSALRDSALNLFNDPMWNQQWYLQDTRMTAALPKLDLHVIPVWQKGITGKG 160
+Q R+KRS FNDP + QQW+L + R P D++V VW++ +TG+G
Sbjct: 132 EQRLLRRAKRSVH-------FNDPKYPQQWHLNNRRS----PGRDINVTGVWERNVTGRG 180
Query: 161 VVITVLDDGLEWNHTDIYANYDPEASYDFNDNDHDPFPRYDPTNENKHGTRCAGEIAMQA 220
V + V+DDG+E DI NY PE SYD N ND DP P D N N HGTRCAGEIA
Sbjct: 181 VTVVVVDDGVEHTIQDIAPNYSPEGSYDLNSNDPDPMPHPDVENGNHHGTRCAGEIAAVP 240
Query: 221 NNHKCGVGVAYNSKVGGIRMLDGIVTDAIEASSIGFNPGHVDIYSASWGPNDDGKTVEGP 280
NN C VGVAY S++ GIR+LDG +TD++EA + + DIYS SWGP+DDGKTV+GP
Sbjct: 241 NNSFCAVGVAYGSRIAGIRVLDGPLTDSMEAVAFNKHYQINDIYSCSWGPDDDGKTVDGP 300
Query: 281 GRLAQKAFEYGVKQGRQGKGSIFVWASGNGGRQGDNCDCDGYTDSIYTISISSASQQGLS 340
+L + A ++GV GRQG GSIFV ASGNGG+ DNC+ DGY +SIYT++I + ++G
Sbjct: 301 HQLGKAALQHGVIAGRQGFGSIFVVASGNGGQHNDNCNYDGYANSIYTVTIGAVDEEGRM 360
Query: 341 PWYAEKCSSTLATSYSSGDYTDQRITSADLH----NDCTETHTGTSASAPLAAGIFALAL 396
P+YAE+C+S LA ++S GD + I + D CTE HTGTSA+APLAAG+ AL L
Sbjct: 361 PFYAEECASMLAVTFSGGDKMLRSIVTTDWDLQKGTGCTEGHTGTSAAAPLAAGMIALML 420
Query: 397 EANPNLTWRDMQHLVVWT-SEYDPLANNPGWKKNGAGLMVNSRFGFGLLNAKALVDLADP 455
+ P LTWRD+QH++V+T + Y+ W N AG + + GFGLLNA LV+ A
Sbjct: 421 QVRPCLTWRDVQHIIVFTATRYED--RRAEWVTNEAGFSHSHQHGFGLLNAWRLVNAA-- 476
Query: 456 RTWRSVP---EKKECVVKDNDFEPRALKANGEVIIEIPTRACEGQENAIKSLEHVQFEAT 512
+ W SVP V+K+N P++ ++ EV+ + E + +K+LEHV +
Sbjct: 477 KIWTSVPYLASYVSPVLKENKAIPQSPRSL-EVLWNVSRMDLE--MSGLKTLEHVAVTVS 533
Query: 513 IEYSRRGDLHVTLTSAAGTSTVLLAERERDTSPNGFKNWDFMSVHTWGENPIGTWTLRIT 572
I + RRG L + L +G +++ A R D+ PNGF +W F +V WGE GT+ L I
Sbjct: 534 ITHPRRGSLELKLFCPSGMMSLIGAPRSMDSDPNGFNDWTFSTVRCWGERARGTYRLVIR 593
Query: 573 DMSGRIQNEGRIVNWKLILHGT 594
D+ G + W+L L+G+
Sbjct: 594 DVGDESFQVGILRQWQLTLYGS 615
>gi|4506775 membrane-bound transcription factor site-1 protease
preproprotein [Homo sapiens]
Length = 1052
Score = 38.1 bits (87), Expect = 0.030
Identities = 32/122 (26%), Positives = 48/122 (39%), Gaps = 8/122 (6%)
Query: 60 QIGSLENHYLFKHKNHPRRSR----RSAFHITKRLSDDDRVIWAEQQYEKERSKRSALRD 115
QI + L ++HP R R F K D V E ++ ++ LR
Sbjct: 105 QIKEKQKAGLLTLEDHPNIKRVTPQRKVFRSLKYAESDPTVPCNETRWSQKWQSSRPLRR 164
Query: 116 SALNLFNDPMWNQQWYLQDTRMTAALPKL---DLHVIPVWQKGITGKGVVITVLDDGLEW 172
++L+L W+ R+ A+P+ L +WQ G TG V + V D GL
Sbjct: 165 ASLSL-GSGFWHATGRHSSRRLLRAIPRQVAQTLQADVLWQMGYTGANVRVAVFDTGLSE 223
Query: 173 NH 174
H
Sbjct: 224 KH 225
>gi|63252863 BTB (POZ) domain containing 12 [Homo sapiens]
Length = 1834
Score = 35.8 bits (81), Expect = 0.15
Identities = 31/99 (31%), Positives = 50/99 (50%), Gaps = 13/99 (13%)
Query: 595 SSQPEHMKQPRVYT-SYNTVQNDRRGVEKMVDPGEEQPTQENPKENTLVSKSPSSSSVGG 653
++QPE P +++ S ++ RRG +P + + E P E+ LV+ + S
Sbjct: 375 TAQPEGSSSPPMFSFSDHSRGLKRRGPTSKKEPRKRRKVDEAPSEDLLVAMALS------ 428
Query: 654 RRDELEEGAPSQAMLRLLQSAFSKNSPPK---QSPKKSP 689
R E+E GA A+ L+SAFS+ P+ +S KK P
Sbjct: 429 -RSEMEPGAAVPAL--RLESAFSERIRPEAENKSRKKKP 464
>gi|109638751 ubiquitin specific protease 6 [Homo sapiens]
Length = 1406
Score = 35.4 bits (80), Expect = 0.20
Identities = 29/85 (34%), Positives = 40/85 (47%), Gaps = 10/85 (11%)
Query: 637 KENTLVSKSPSSSSVGGRRDELEEGAPSQAMLRLLQSAFSKNSPPKQSPKKSPSAK--LN 694
KE+ L+SKSPSS S +G+PS + SKNS P SP+ +K L
Sbjct: 1151 KEDMLLSKSPSSLSAN--ISSSPKGSPSSSRKSGTSCPSSKNSSPNSSPRTLGRSKGRLR 1208
Query: 695 IPYENFYEALEKLNKPSQLKDSEDS 719
+P + NKPS K + D+
Sbjct: 1209 LP------QIGSKNKPSSSKKNLDA 1227
>gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo
sapiens]
Length = 2462
Score = 33.1 bits (74), Expect = 0.97
Identities = 28/121 (23%), Positives = 52/121 (42%), Gaps = 5/121 (4%)
Query: 597 QPEHMKQPRVYTSYNTVQNDRRGVEKMVDPGEEQPTQENPKENTLVSKSPSSSSVGGRRD 656
Q + +QP +S + D + EK + EE+P EN KE+ L K+ +S G +
Sbjct: 504 QQQQQQQPMPRSSQE--EKDEKEKEKEAEKEEEKPEVENDKEDLLKEKTDDTS---GEDN 558
Query: 657 ELEEGAPSQAMLRLLQSAFSKNSPPKQSPKKSPSAKLNIPYENFYEALEKLNKPSQLKDS 716
+ +E S+ K + ++ S + P ++ A +LN+ S+ +
Sbjct: 559 DEKEAVASKGRKTANSQGRRKGRITRSMANEANSEEAITPQQSAELASMELNESSRWTEE 618
Query: 717 E 717
E
Sbjct: 619 E 619
>gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo
sapiens]
Length = 2524
Score = 33.1 bits (74), Expect = 0.97
Identities = 28/121 (23%), Positives = 52/121 (42%), Gaps = 5/121 (4%)
Query: 597 QPEHMKQPRVYTSYNTVQNDRRGVEKMVDPGEEQPTQENPKENTLVSKSPSSSSVGGRRD 656
Q + +QP +S + D + EK + EE+P EN KE+ L K+ +S G +
Sbjct: 504 QQQQQQQPMPRSSQE--EKDEKEKEKEAEKEEEKPEVENDKEDLLKEKTDDTS---GEDN 558
Query: 657 ELEEGAPSQAMLRLLQSAFSKNSPPKQSPKKSPSAKLNIPYENFYEALEKLNKPSQLKDS 716
+ +E S+ K + ++ S + P ++ A +LN+ S+ +
Sbjct: 559 DEKEAVASKGRKTANSQGRRKGRITRSMANEANSEEAITPQQSAELASMELNESSRWTEE 618
Query: 717 E 717
E
Sbjct: 619 E 619
>gi|31317307 proprotein convertase subtilisin/kexin type 9
preproprotein [Homo sapiens]
Length = 692
Score = 32.7 bits (73), Expect = 1.3
Identities = 18/53 (33%), Positives = 28/53 (52%), Gaps = 2/53 (3%)
Query: 374 CTETHTGTSASAPLAAGIFALALEANPNLTWRDMQHLVVWTSEYDPLANNPGW 426
C + +GTS +A AGI A+ L A P LT +++ ++ S D + N W
Sbjct: 378 CFVSQSGTSQAAAHVAGIAAMMLSAEPELTLAELRQRLIHFSAKDVI--NEAW 428
>gi|28827782 zinc fingers and homeoboxes 3 [Homo sapiens]
Length = 956
Score = 32.3 bits (72), Expect = 1.7
Identities = 28/95 (29%), Positives = 45/95 (47%), Gaps = 3/95 (3%)
Query: 636 PKENTLVSKS-PSSSSVGGRRDELE-EGAPSQAMLRLLQSAFSKNSPPKQSPKKSPSAKL 693
P + +V +S P S+S E EGA QA + + ++ K K KK + K
Sbjct: 145 PDNHVVVEQSIPESTSTPDLAGEPSAEGADGQAEIIITKTPIMKIMKGKAEAKKIHTLKE 204
Query: 694 NIPYENFYEALEKLNK-PSQLKDSEDSLYNDYVDV 727
N+P + EAL KL+ ++++ + S N V V
Sbjct: 205 NVPSQPVGEALPKLSTGEMEVREGDHSFINGAVPV 239
>gi|109134351 zinc finger and BTB domain containing 44 [Homo
sapiens]
Length = 453
Score = 32.3 bits (72), Expect = 1.7
Identities = 20/51 (39%), Positives = 28/51 (54%), Gaps = 8/51 (15%)
Query: 631 PTQENPKENTLVSKSPSSSSVGGRRDELEEGAPSQAMLRLLQSAFSKNSPP 681
P E +E+ L+S P SSS+G + + EG P+ LQS S N+PP
Sbjct: 321 PGSEQVQEDLLIS--PQSSSIGSVDEGVSEGLPT------LQSTSSTNAPP 363
>gi|221139761 zinc finger protein 853 [Homo sapiens]
Length = 659
Score = 32.0 bits (71), Expect = 2.2
Identities = 23/92 (25%), Positives = 41/92 (44%), Gaps = 6/92 (6%)
Query: 627 GEEQPTQENPKENTLVSKSPSSSSVGGRRDELEEGAPSQAMLRLLQSAFSKNSPPKQSPK 686
G E +E P+E + P+ S+ G + EE P Q L+L Q + P+Q P+
Sbjct: 48 GSESQEEEEPQERNSSPQRPAVSAPVGASEIAEETRPGQRELQLQQ--LEQQPEPQQQPQ 105
Query: 687 ----KSPSAKLNIPYENFYEALEKLNKPSQLK 714
+ P L + + + ++L++ Q K
Sbjct: 106 HEQLQQPQPHLELQQQPQQDGQQQLSQLQQEK 137
>gi|88758580 cyclin L2 isoform A [Homo sapiens]
Length = 520
Score = 32.0 bits (71), Expect = 2.2
Identities = 31/129 (24%), Positives = 54/129 (41%), Gaps = 16/129 (12%)
Query: 577 RIQNEGRIVNWKLILHGTSS---QPEHMKQPRV----YTSYNTVQNDRRGVEKMVDPGEE 629
+ Q G + +L GTS P+ ++ P+ S +V+N +R +E +
Sbjct: 309 KAQARGLLPGGTQVLDGTSGFSPAPKLVESPKEGKGSKPSPLSVKNTKRRLEGAKKAKAD 368
Query: 630 QPTQENPKENTLVSKSPS---------SSSVGGRRDELEEGAPSQAMLRLLQSAFSKNSP 680
P PK S+S S S S +R + + G+ S +S +SP
Sbjct: 369 SPVNGLPKGRESRSRSRSREQSYSRSPSRSASPKRRKSDSGSTSGGSKSQSRSRSRSDSP 428
Query: 681 PKQSPKKSP 689
P+Q+P+ +P
Sbjct: 429 PRQAPRSAP 437
>gi|38788274 bromodomain PHD finger transcription factor isoform 1
[Homo sapiens]
Length = 2920
Score = 32.0 bits (71), Expect = 2.2
Identities = 35/134 (26%), Positives = 57/134 (42%), Gaps = 21/134 (15%)
Query: 596 SQPEHMKQPRVYTSYNTVQNDRRGVEKMVDPGEEQPTQENPKENTLVSKSPSSSSVGGRR 655
+QPE QP V T TV + P E QPT + + ++S S+V G +
Sbjct: 2289 AQPEVQTQPEVQTQ-TTVSSHV--------PSEAQPTHAQSSKPQVAAQSQPQSNVQG-Q 2338
Query: 656 DELEEGAPSQAMLRLLQSAFSKNSPPKQSPKKS---------PSAKLNIPYENFYEALEK 706
+ +PSQ +R S S+ SP +QS ++ P L IP + ++ +
Sbjct: 2339 SPVRVQSPSQTRIR--PSTPSQLSPGQQSQVQTTTSQPIPIQPHTSLQIPSQGQPQSQPQ 2396
Query: 707 LNKPSQLKDSEDSL 720
+ +Q S +L
Sbjct: 2397 VQSSTQTLSSGQTL 2410
>gi|145580582 uromodulin-like 1 isoform 2 precursor [Homo sapiens]
Length = 1446
Score = 31.6 bits (70), Expect = 2.8
Identities = 19/94 (20%), Positives = 42/94 (44%), Gaps = 1/94 (1%)
Query: 618 RGVEKMVDPGEEQPTQENPKENTLVSKSPSSSSVG-GRRDELEEGAPSQAMLRLLQSAFS 676
+G V+P + P+Q + ++ + SPS S G ++ S + Q + S
Sbjct: 645 QGSPSQVNPSQGSPSQGSLRQESTSQASPSQRSTSQGSPSQVNPSQRSTSHANSSQGSPS 704
Query: 677 KNSPPKQSPKKSPSAKLNIPYENFYEALEKLNKP 710
+ SP ++SP + +++ + + N + + P
Sbjct: 705 QGSPSQESPSQGSTSQASPSHRNTIGVIGTTSSP 738
>gi|58530876 melanoma antigen family C, 1 [Homo sapiens]
Length = 1142
Score = 31.2 bits (69), Expect = 3.7
Identities = 27/105 (25%), Positives = 46/105 (43%), Gaps = 13/105 (12%)
Query: 630 QPTQENPKENTLVSKSPSSSSVGGRRDELEEGAPSQAMLRLLQSAFSKNSP--PKQSPKK 687
Q E P ++ L +SP SS L + +P + S+ SK+SP P QSP
Sbjct: 799 QSPPEGPAQSPL--QSPVSSFPSSTSSSLSQSSPVSSFPSSTSSSLSKSSPESPLQSPVI 856
Query: 688 SPSAKLNI---------PYENFYEALEKLNKPSQLKDSEDSLYND 723
S S+ ++ P + + + + L + L DSE + ++
Sbjct: 857 SFSSSTSLSPFSEESSSPVDEYTSSSDTLLESDSLTDSESLIESE 901
>gi|21687218 CD300 molecule-like family member g [Homo sapiens]
Length = 332
Score = 30.8 bits (68), Expect = 4.8
Identities = 24/101 (23%), Positives = 41/101 (40%), Gaps = 11/101 (10%)
Query: 596 SQPEHMKQPRVYTSYNTVQNDRRGVEKMVDPGEEQPTQENPKENTLVSKSPSSSSVGGRR 655
+QP + P +Y + T + + G E PG Q E + T S P++S G
Sbjct: 155 TQPPGLTSPGLYPAATTAKQGKTGAEAPPLPGTSQYGHERTSQYTGTSPHPATSPPAG-- 212
Query: 656 DELEEGAPSQAMLRLLQSAFSKNSPPKQSPKKSPSAKLNIP 696
S+ ++L ++ SP S P +++IP
Sbjct: 213 -------SSRPPMQLNSTSAEDTSPALSSGSSKP--RVSIP 244
>gi|153792764 hypothetical protein LOC57624 [Homo sapiens]
Length = 653
Score = 30.4 bits (67), Expect = 6.3
Identities = 24/129 (18%), Positives = 53/129 (41%), Gaps = 17/129 (13%)
Query: 633 QENPKENTLVSKSPSSSSVGGRRDELEEGAPSQAMLRLLQSAFSKNSPPKQSPKKSPSAK 692
+ +P S SS+ + + E + A R +SK PP + PK++P+ +
Sbjct: 144 KRDPSTKLSTSSETVSSTAASKSGKTPERTEASAKPRPHSDEYSKKIPPPK-PKRNPNTQ 202
Query: 693 LNIPYENFY--------------EALEKLNKPSQLKDSEDSLYNDYVDVFYNTKPYKHRD 738
L+ ++ Y +L ++ P+ + E+ +Y + V + ++ D
Sbjct: 203 LSTSFDETYIKKHGPRRTSLPRDSSLSQMGSPAGDPEEEEPVYIEMVGNI--LRDFRKED 260
Query: 739 DRLLQALVD 747
D +A+ +
Sbjct: 261 DDQSEAVYE 269
>gi|239753409 PREDICTED: similar to hCG1811893 [Homo sapiens]
Length = 669
Score = 30.4 bits (67), Expect = 6.3
Identities = 24/129 (18%), Positives = 53/129 (41%), Gaps = 17/129 (13%)
Query: 633 QENPKENTLVSKSPSSSSVGGRRDELEEGAPSQAMLRLLQSAFSKNSPPKQSPKKSPSAK 692
+ +P S SS+ + + E + A R +SK PP + PK++P+ +
Sbjct: 144 KRDPSTKLSTSSETVSSTAASKSGKTPERTEASAKPRPHSDEYSKKIPPPK-PKRNPNTQ 202
Query: 693 LNIPYENFY--------------EALEKLNKPSQLKDSEDSLYNDYVDVFYNTKPYKHRD 738
L+ ++ Y +L ++ P+ + E+ +Y + V + ++ D
Sbjct: 203 LSTSFDETYIKKHGPRRTSLPRDSSLSQMGSPAGDPEEEEPVYIEMVGNI--LRDFRKED 260
Query: 739 DRLLQALVD 747
D +A+ +
Sbjct: 261 DDQSEAVYE 269
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.131 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 31,042,302
Number of Sequences: 37866
Number of extensions: 1477259
Number of successful extensions: 3127
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 15
Number of HSP's successfully gapped in prelim test: 27
Number of HSP's that attempted gapping in prelim test: 3049
Number of HSP's gapped (non-prelim): 54
length of query: 753
length of database: 18,247,518
effective HSP length: 110
effective length of query: 643
effective length of database: 14,082,258
effective search space: 9054891894
effective search space used: 9054891894
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.